# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Sugar_tr PF00083.24 KRZ98213.1 - 3.1e-06 26.3 1.3 3.9e-06 26.0 1.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter PrmA PF06325.13 KRZ98215.1 - 2.7e-05 23.7 0.0 2.8e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 KRZ98215.1 - 0.0019 18.0 0.0 0.0021 17.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KRZ98215.1 - 0.0031 17.1 0.1 0.0053 16.3 0.1 1.3 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 KRZ98215.1 - 0.0046 17.6 0.2 0.022 15.5 0.1 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KRZ98215.1 - 0.026 14.3 0.0 0.034 13.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_9 PF08003.11 KRZ98215.1 - 0.045 12.7 0.0 0.045 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) CMAS PF02353.20 KRZ98215.1 - 0.077 12.3 0.2 0.12 11.6 0.1 1.4 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase MFS_1 PF07690.16 KRZ98216.1 - 7.6e-09 34.9 4.4 8.1e-09 34.9 4.4 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KRZ98216.1 - 5.4e-05 22.2 2.3 5.4e-05 22.2 2.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Mannosidase_ig PF17786.1 KRZ98217.1 - 0.00013 22.5 0.0 0.00025 21.6 0.0 1.5 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain Ig_mannosidase PF17753.1 KRZ98217.1 - 0.00044 19.9 0.1 0.00061 19.5 0.1 1.3 1 0 0 1 1 1 1 Ig-fold domain DUF5314 PF17241.2 KRZ98218.1 - 9.8e-10 38.4 0.1 1.1e-09 38.2 0.1 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5314) G2BR PF18442.1 KRZ98218.1 - 0.021 14.4 2.3 1.3 8.8 0.4 2.4 2 0 0 2 2 2 0 E3 gp78 Ube2g2-binding region (G2BR) DIM1 PF02966.16 KRZ98218.1 - 0.022 14.6 0.3 0.026 14.3 0.3 1.2 1 0 0 1 1 1 0 Mitosis protein DIM1 Sigma54_AID PF00309.20 KRZ98218.1 - 0.075 12.9 1.0 3.3 7.6 0.1 2.2 2 0 0 2 2 2 0 Sigma-54 factor, Activator interacting domain (AID) Sugar_tr PF00083.24 KRZ98219.1 - 3.5e-11 42.6 0.7 3.6e-11 42.6 0.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter ABC_tran PF00005.27 KRZ98220.1 - 2.7e-07 31.2 0.0 3.5e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 ABC transporter COX2 PF00116.20 KRZ98221.1 - 4.5e-42 142.7 0.2 5e-42 142.6 0.2 1.0 1 0 0 1 1 1 1 Cytochrome C oxidase subunit II, periplasmic domain Sugar_tr PF00083.24 KRZ98222.1 - 8.1e-42 143.6 1.2 8.9e-42 143.5 1.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KRZ98222.1 - 3.1e-06 26.4 6.1 3.6e-06 26.1 6.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily PDR_CDR PF06422.12 KRZ98223.1 - 2.8e-33 113.7 0.1 4.2e-33 113.1 0.1 1.3 1 0 0 1 1 1 1 CDR ABC transporter ABC2_membrane PF01061.24 KRZ98223.1 - 0.0025 17.2 1.1 0.023 14.1 0.1 2.0 2 0 0 2 2 2 1 ABC-2 type transporter ADH_zinc_N PF00107.26 KRZ98224.1 - 1.6e-14 54.0 0.1 2.7e-14 53.3 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KRZ98224.1 - 0.01 16.9 0.1 0.021 15.9 0.1 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase PDR_CDR PF06422.12 KRZ98225.1 - 2.2e-33 114.0 0.3 3.2e-33 113.5 0.3 1.2 1 0 0 1 1 1 1 CDR ABC transporter ABC2_membrane PF01061.24 KRZ98225.1 - 0.0021 17.5 0.9 0.012 15.0 0.1 2.0 2 0 0 2 2 2 1 ABC-2 type transporter Pax2_C PF12403.8 KRZ98225.1 - 0.066 13.3 0.0 0.098 12.7 0.0 1.2 1 0 0 1 1 1 0 Paired-box protein 2 C terminal LRR19-TM PF15176.6 KRZ98225.1 - 0.12 12.3 0.1 0.2 11.6 0.0 1.5 1 1 0 1 1 1 0 Leucine-rich repeat family 19 TM domain EVC2_like PF12297.8 KRZ98225.1 - 0.15 10.7 0.0 0.19 10.4 0.0 1.1 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein ABC_tran PF00005.27 KRZ98227.1 - 1.5e-15 57.9 0.0 1.7e-15 57.7 0.0 1.0 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 KRZ98227.1 - 0.0022 18.4 0.0 0.0031 17.9 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 KRZ98227.1 - 0.0035 17.1 0.0 0.0043 16.8 0.0 1.1 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KRZ98227.1 - 0.0044 16.9 0.3 0.0072 16.2 0.3 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_28 PF13521.6 KRZ98227.1 - 0.024 14.9 0.1 0.03 14.6 0.1 1.4 1 1 0 1 1 1 0 AAA domain dNK PF01712.19 KRZ98227.1 - 0.027 14.3 0.0 0.031 14.1 0.0 1.2 1 0 0 1 1 1 0 Deoxynucleoside kinase AAA_23 PF13476.6 KRZ98227.1 - 0.031 14.8 0.0 0.033 14.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain PRK PF00485.18 KRZ98227.1 - 0.11 12.3 0.4 0.32 10.7 0.1 1.8 1 1 1 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 KRZ98227.1 - 0.13 12.8 0.0 0.16 12.5 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_21 PF13304.6 KRZ98227.1 - 0.15 11.8 3.1 9.5 5.9 0.2 2.9 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system MFS_1 PF07690.16 KRZ98229.1 - 1.7e-12 47.0 8.1 1.8e-12 46.8 8.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily PTSIIB_sorb PF03830.15 KRZ98231.1 - 0.011 15.9 0.8 0.018 15.3 0.8 1.3 1 0 0 1 1 1 0 PTS system sorbose subfamily IIB component Peptidase_M3_N PF08439.10 KRZ98231.1 - 0.034 14.4 1.3 0.1 12.9 0.5 2.2 2 0 0 2 2 2 0 Oligopeptidase F RVT_2 PF07727.14 KRZ98232.1 - 8.2e-12 45.3 0.0 1.1e-11 44.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) COX2 PF00116.20 KRZ98233.1 - 1.9e-47 160.1 0.1 2.2e-47 159.9 0.1 1.0 1 0 0 1 1 1 1 Cytochrome C oxidase subunit II, periplasmic domain DUF1593 PF07632.11 KRZ98235.1 - 8.6e-23 81.1 0.8 9.8e-23 80.9 0.1 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1593) ADH_N PF08240.12 KRZ98236.1 - 4.3e-31 107.0 2.7 4.3e-31 107.0 2.7 1.5 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 KRZ98236.1 - 0.00088 18.8 0.1 0.0016 18.0 0.1 1.4 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N PF00107.26 KRZ98236.1 - 0.042 13.8 0.0 0.071 13.1 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Hexapep PF00132.24 KRZ98236.1 - 0.15 11.9 2.2 4.4 7.2 1.4 3.3 2 1 0 2 2 2 0 Bacterial transferase hexapeptide (six repeats) DUF4954 PF16314.5 KRZ98236.1 - 0.28 9.3 0.3 0.38 8.8 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) Hexapep_2 PF14602.6 KRZ98236.1 - 7.3 6.4 9.5 1.5 8.6 3.3 3.0 3 1 0 3 3 3 0 Hexapeptide repeat of succinyl-transferase PFU PF09070.11 KRZ98237.1 - 0.016 15.4 0.6 0.023 14.9 0.6 1.3 1 1 0 1 1 1 0 PFU (PLAA family ubiquitin binding) PolC_DP2 PF03833.13 KRZ98237.1 - 0.089 10.6 0.7 0.093 10.6 0.7 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Arginase PF00491.21 KRZ98238.1 - 2.1e-33 116.0 0.1 2.4e-33 115.8 0.1 1.0 1 0 0 1 1 1 1 Arginase family DLH PF01738.18 KRZ98239.1 - 9.3e-20 71.1 0.0 1e-19 71.0 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Transketolase_N PF00456.21 KRZ98241.1 - 1.1e-81 274.4 0.1 1.2e-81 274.2 0.1 1.0 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain DXP_synthase_N PF13292.6 KRZ98241.1 - 6.9e-08 32.0 0.1 3.1e-07 29.9 0.1 1.7 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.20 KRZ98241.1 - 4.5e-06 25.8 0.0 5.4e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 KRZ98241.1 - 0.0024 17.7 0.4 0.0047 16.7 0.1 1.7 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Borrelia_P13 PF05628.12 KRZ98241.1 - 0.037 14.0 0.0 0.084 12.8 0.0 1.5 2 0 0 2 2 2 0 Borrelia membrane protein P13 Cupin_2 PF07883.11 KRZ98242.1 - 1.6e-17 62.9 0.4 2.4e-17 62.4 0.4 1.2 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 KRZ98242.1 - 5.8e-06 26.2 0.1 9.4e-06 25.6 0.1 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain MatE PF01554.18 KRZ98243.1 - 2.3e-16 59.8 12.4 4.1e-16 59.1 12.4 1.4 1 0 0 1 1 1 1 MatE FAA_hydrolase PF01557.18 KRZ98244.1 - 7.3e-55 186.0 0.0 1.1e-54 185.4 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family 2OG-FeII_Oxy PF03171.20 KRZ98245.1 - 6.8e-11 42.6 0.0 1.1e-10 41.8 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fungal_trans PF04082.18 KRZ98246.1 - 3.4e-05 23.0 0.3 5.9e-05 22.2 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain ABC_tran PF00005.27 KRZ98247.1 - 0.00013 22.5 0.0 0.00019 22.0 0.0 1.3 1 0 0 1 1 1 1 ABC transporter DUF3698 PF12479.8 KRZ98248.1 - 1.8e-27 96.0 0.0 2.4e-27 95.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3698) ADH_N PF08240.12 KRZ98250.1 - 1.3e-23 83.0 6.8 1.6e-23 82.6 6.8 1.1 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain LysM PF01476.20 KRZ98252.1 - 0.012 15.7 0.0 0.052 13.6 0.0 2.0 2 0 0 2 2 2 0 LysM domain JAB PF01398.21 KRZ98254.1 - 2e-10 40.7 0.1 6.1e-10 39.1 0.0 1.9 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Angiomotin_C PF12240.8 KRZ98254.1 - 0.068 12.7 1.5 0.12 12.0 1.5 1.4 1 0 0 1 1 1 0 Angiomotin C terminal DUF2089 PF09862.9 KRZ98254.1 - 0.089 12.8 0.7 0.53 10.3 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2089) Globin PF00042.22 KRZ98257.1 - 1.6e-08 35.0 0.0 3.7e-08 33.9 0.0 1.6 1 1 0 1 1 1 1 Globin Protoglobin PF11563.8 KRZ98257.1 - 0.015 15.2 0.0 0.025 14.5 0.0 1.5 1 1 0 1 1 1 0 Protoglobin Transposase_22 PF02994.14 KRZ98259.1 - 1.6e-43 146.9 3.2 2.8e-43 146.0 3.2 1.4 1 0 0 1 1 1 1 L1 transposable element RBD-like domain Tnp_22_dsRBD PF17490.2 KRZ98259.1 - 2.5e-40 136.3 0.2 4.7e-40 135.4 0.2 1.5 1 0 0 1 1 1 1 L1 transposable element dsRBD-like domain FAF PF11250.8 KRZ98259.1 - 0.013 15.7 0.2 0.069 13.4 0.2 2.1 2 0 0 2 2 2 0 Fantastic Four meristem regulator GTP_EFTU PF00009.27 KRZ98260.1 - 2.1e-50 171.0 0.6 2.4e-50 170.8 0.6 1.0 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KRZ98260.1 - 0.00012 22.1 0.1 0.0034 17.5 0.1 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 KRZ98260.1 - 0.035 13.3 0.2 0.16 11.1 0.1 2.0 1 1 1 2 2 2 0 G-protein alpha subunit Dynamin_N PF00350.23 KRZ98260.1 - 0.053 13.6 0.2 12 5.9 0.0 2.4 3 0 0 3 3 3 0 Dynamin family FeoB_N PF02421.18 KRZ98260.1 - 0.066 12.7 0.1 5.4 6.5 0.0 2.7 3 0 0 3 3 3 0 Ferrous iron transport protein B Polyoma_lg_T_C PF06431.11 KRZ98260.1 - 0.11 11.3 0.0 0.43 9.4 0.0 1.8 2 0 0 2 2 2 0 Polyomavirus large T antigen C-terminus GTP_EFTU_D3 PF03143.17 KRZ98261.1 - 1.7e-40 137.8 0.0 3.2e-40 136.9 0.0 1.5 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KRZ98261.1 - 5.2e-08 33.2 0.1 8.1e-08 32.5 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Helicase_C PF00271.31 KRZ98262.1 - 1.4e-10 41.5 0.0 2.8e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain TNFR_c6 PF00020.18 KRZ98262.1 - 1.6 9.2 5.3 1.4 9.4 0.9 2.5 2 0 0 2 2 2 0 TNFR/NGFR cysteine-rich region ABC2_membrane PF01061.24 KRZ98263.1 - 2.2e-41 141.6 20.1 2.2e-41 141.6 20.1 1.9 2 0 0 2 2 2 1 ABC-2 type transporter PDR_CDR PF06422.12 KRZ98263.1 - 2.9e-33 113.6 5.6 4e-33 113.2 0.1 2.5 2 0 0 2 2 2 1 CDR ABC transporter FWWh PF14922.6 KRZ98263.1 - 0.039 13.9 0.2 0.078 12.9 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function ABC2_membrane_3 PF12698.7 KRZ98263.1 - 0.066 12.3 29.4 0.043 12.9 25.4 2.3 1 1 1 2 2 2 0 ABC-2 family transporter protein ABC2_membrane PF01061.24 KRZ98264.1 - 4.3e-40 137.4 20.1 4.3e-40 137.4 20.1 2.0 2 0 0 2 2 2 1 ABC-2 type transporter PDR_CDR PF06422.12 KRZ98264.1 - 1.1e-32 111.8 6.1 3e-32 110.4 0.0 2.9 3 0 0 3 3 3 1 CDR ABC transporter ABC2_membrane_3 PF12698.7 KRZ98264.1 - 0.002 17.3 23.4 0.0074 15.4 23.2 2.2 1 1 0 1 1 1 1 ABC-2 family transporter protein DUF3290 PF11694.8 KRZ98264.1 - 0.0028 17.6 0.1 0.0073 16.3 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3290) DUF2304 PF10066.9 KRZ98264.1 - 1.1 9.5 17.6 0.076 13.2 5.5 2.9 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2304) CPP1-like PF11833.8 KRZ98264.1 - 1.5 8.4 8.1 0.22 11.2 3.2 2.1 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Zn_clus PF00172.18 KRZ98266.1 - 5.9e-09 35.9 7.8 5.9e-09 35.9 7.8 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KRZ98266.1 - 0.00087 18.4 0.6 0.0034 16.4 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain CDC45 PF02724.14 KRZ98266.1 - 0.017 13.4 3.8 0.021 13.2 3.8 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF5089 PF17002.5 KRZ98266.1 - 2.3 8.0 12.8 0.92 9.3 0.7 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF5089) ADH_N_2 PF16884.5 KRZ98267.1 - 5.1e-19 68.2 0.0 6e-19 67.9 0.0 1.1 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase MFS_1 PF07690.16 KRZ98269.1 - 2.8e-20 72.6 5.7 3.3e-20 72.3 5.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KRZ98269.1 - 0.00045 19.2 2.0 0.031 13.1 0.2 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter BT1 PF03092.16 KRZ98269.1 - 0.72 8.0 4.7 4.2 5.5 0.2 2.3 2 1 1 3 3 3 0 BT1 family SPC25 PF06703.11 KRZ98269.1 - 0.83 9.4 2.9 0.59 9.9 0.6 1.9 2 1 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Zn_clus PF00172.18 KRZ98270.1 - 4.1e-08 33.2 7.1 8.6e-08 32.2 7.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KRZ98270.1 - 0.011 14.8 0.0 0.023 13.7 0.0 1.6 1 0 0 1 1 1 0 Fungal specific transcription factor domain NmrA PF05368.13 KRZ98271.1 - 3.4e-12 46.4 0.0 4e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family CSTF2_hinge PF14327.6 KRZ98272.1 - 2.2e-22 79.3 1.2 2.2e-22 79.3 1.2 3.5 5 0 0 5 5 5 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 KRZ98272.1 - 2.1e-09 37.1 0.0 4.8e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 KRZ98272.1 - 1e-08 34.6 1.9 5.4e-08 32.3 1.9 2.4 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal DUF4199 PF13858.6 KRZ98272.1 - 2 8.8 3.8 4 7.8 3.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Say1_Mug180 PF10340.9 KRZ98273.1 - 3.4e-27 95.3 0.6 4.2e-27 95.0 0.6 1.2 1 1 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_3 PF07859.13 KRZ98273.1 - 5.8e-14 52.5 0.0 8.8e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KRZ98273.1 - 0.017 14.4 0.0 0.025 13.8 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 mRNA_decap_C PF16741.5 KRZ98273.1 - 0.1 11.9 0.2 0.32 10.3 0.0 1.9 2 0 0 2 2 2 0 mRNA-decapping enzyme C-terminus COesterase PF00135.28 KRZ98273.1 - 0.2 10.5 0.1 0.49 9.2 0.0 1.6 2 0 0 2 2 2 0 Carboxylesterase family Flocculin_t3 PF13928.6 KRZ98274.1 - 3.4e-14 53.1 23.2 3.4e-14 53.1 23.2 2.4 2 0 0 2 2 2 1 Flocculin type 3 repeat Asp_protease_2 PF13650.6 KRZ98275.1 - 0.0069 17.0 0.1 0.014 16.0 0.1 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KRZ98275.1 - 0.016 15.8 0.1 0.034 14.7 0.1 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 KRZ98276.1 - 1e-09 38.5 0.1 1.8e-09 37.8 0.1 1.3 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.23 KRZ98276.1 - 0.00035 20.5 4.2 0.00061 19.8 4.2 1.4 1 0 0 1 1 1 1 Zinc knuckle eIF3g PF12353.8 KRZ98276.1 - 0.0049 17.3 0.7 0.011 16.1 0.7 1.7 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G DUF3549 PF12069.8 KRZ98276.1 - 0.026 13.6 0.0 0.038 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3549) DUF5595 PF18077.1 KRZ98276.1 - 0.042 13.9 1.0 0.42 10.7 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) Pkinase PF00069.25 KRZ98277.1 - 2.5e-06 27.1 1.7 4.5e-06 26.2 1.1 1.7 1 1 1 2 2 2 1 Protein kinase domain RIO1 PF01163.22 KRZ98277.1 - 1.6e-05 24.6 0.1 3.6e-05 23.4 0.1 1.6 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KRZ98277.1 - 0.0014 18.6 0.0 0.0021 18.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KRZ98277.1 - 0.0041 16.4 0.6 0.011 15.0 0.2 1.8 1 1 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KRZ98277.1 - 0.086 11.6 0.6 0.17 10.6 0.1 1.6 2 0 0 2 2 2 0 Fungal protein kinase MFS_1 PF07690.16 KRZ98278.1 - 3.3e-20 72.3 15.7 4e-20 72.1 15.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 KRZ98279.1 - 5e-05 22.4 5.2 6.7e-05 22.0 5.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3522 PF12036.8 KRZ98279.1 - 0.07 13.4 1.8 0.57 10.4 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3522) DUF1689 PF07954.11 KRZ98279.1 - 0.076 13.4 0.1 0.12 12.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1689) Chordopox_A13L PF05961.11 KRZ98279.1 - 0.38 11.0 0.0 0.38 11.0 0.0 1.9 2 0 0 2 2 2 0 Chordopoxvirus A13L protein CcmD PF04995.14 KRZ98279.1 - 1.5 8.9 4.7 6 7.0 4.7 2.0 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) FtsX PF02687.21 KRZ98279.1 - 4.1 7.9 8.9 5.4 7.6 6.2 2.5 1 1 1 2 2 2 0 FtsX-like permease family Polysacc_synt_C PF14667.6 KRZ98279.1 - 8.1 6.5 14.1 1.8 8.6 5.6 2.2 1 1 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain DUF3698 PF12479.8 KRZ98280.1 - 1.5e-27 96.3 0.0 4e-27 94.9 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3698) Ribosomal_S19e PF01090.19 KRZ98281.1 - 1.1e-52 177.4 0.0 1.2e-52 177.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Flocculin_t3 PF13928.6 KRZ98283.1 - 8.9e-11 42.1 19.4 8.9e-11 42.1 19.4 3.9 4 0 0 4 4 4 1 Flocculin type 3 repeat Sugar_tr PF00083.24 KRZ98285.1 - 1e-22 80.6 8.3 1.1e-22 80.5 8.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter DUF2316 PF10078.9 KRZ98285.1 - 0.092 13.0 0.0 2 8.7 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2316) tRNA_int_endo PF01974.17 KRZ98287.1 - 1.8e-22 79.2 0.0 3.2e-22 78.4 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 KRZ98287.1 - 0.1 12.3 0.1 3.4 7.4 0.0 2.4 2 0 0 2 2 2 0 tRNA intron endonuclease, N-terminal domain DUF1977 PF09320.11 KRZ98288.1 - 2.2e-32 111.4 1.1 2.2e-32 111.4 1.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1977) DnaJ PF00226.31 KRZ98288.1 - 6.5e-24 83.8 1.2 1.3e-23 82.9 1.2 1.5 1 0 0 1 1 1 1 DnaJ domain ApoC-I PF04691.12 KRZ98288.1 - 0.015 15.2 0.1 0.03 14.2 0.1 1.5 1 0 0 1 1 1 0 Apolipoprotein C-I (ApoC-1) GntP_permease PF02447.16 KRZ98288.1 - 0.19 10.4 0.0 0.25 10.0 0.0 1.1 1 0 0 1 1 1 0 GntP family permease Asp_protease_2 PF13650.6 KRZ98290.1 - 4.8e-10 39.9 0.0 7.8e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KRZ98290.1 - 5.6e-09 36.4 0.0 8.5e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Peptidase_A2E PF12382.8 KRZ98290.1 - 0.00018 21.5 0.3 0.00044 20.3 0.1 1.7 2 0 0 2 2 2 1 Retrotransposon peptidase RVP_2 PF08284.11 KRZ98290.1 - 0.00054 19.7 0.0 0.00094 19.0 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.20 KRZ98290.1 - 0.00095 19.4 0.1 0.0023 18.2 0.0 1.7 2 0 0 2 2 2 1 Retroviral aspartyl protease Peptidase_A2B PF12384.8 KRZ98290.1 - 0.017 14.7 0.0 0.026 14.1 0.0 1.2 1 0 0 1 1 1 0 Ty3 transposon peptidase Asp_protease PF09668.10 KRZ98290.1 - 0.039 13.8 0.0 0.066 13.0 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease Retrotrans_gag PF03732.17 KRZ98291.1 - 4.9e-12 46.0 2.0 1e-11 44.9 0.1 2.1 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.23 KRZ98291.1 - 4.3e-07 29.7 3.2 6.6e-07 29.1 3.2 1.3 1 0 0 1 1 1 1 Zinc knuckle eIF3g PF12353.8 KRZ98291.1 - 0.0023 18.3 0.9 0.0047 17.3 0.7 1.8 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 3 subunit G DUF4391 PF14335.6 KRZ98291.1 - 0.031 14.0 0.4 0.12 12.0 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4391) zf-CCHC_3 PF13917.6 KRZ98291.1 - 0.28 11.2 3.9 0.55 10.3 3.9 1.5 1 0 0 1 1 1 0 Zinc knuckle MFS_1 PF07690.16 KRZ98292.1 - 2e-24 86.2 23.0 2.8e-24 85.7 23.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 KRZ98293.1 - 1.5e-32 112.9 13.7 1.5e-32 112.9 13.7 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF3792 PF12670.7 KRZ98293.1 - 0.038 14.2 9.8 0.055 13.6 1.6 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3792) Integrase_H2C2 PF17921.1 KRZ98294.1 - 4.6e-19 68.3 0.0 1.2e-18 67.0 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 KRZ98294.1 - 1.3e-09 38.3 0.0 3e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 KRZ98294.1 - 0.0029 17.8 0.0 0.021 15.0 0.0 2.4 2 0 0 2 2 2 1 H2C2 zinc finger Rad10 PF03834.14 KRZ98294.1 - 0.091 12.8 0.0 0.55 10.3 0.0 2.3 2 0 0 2 2 2 0 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) DUSP PF06337.12 KRZ98294.1 - 0.25 12.0 4.8 7.5 7.2 0.2 3.3 3 0 0 3 3 3 0 DUSP domain ADH_zinc_N PF00107.26 KRZ98295.1 - 1.8e-21 76.5 0.3 3.3e-21 75.6 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KRZ98295.1 - 2.8e-12 47.8 0.0 4.9e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KRZ98295.1 - 2.8e-10 40.0 0.0 3.3e-09 36.6 0.0 2.3 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AA_permease PF00324.21 KRZ98296.1 - 4.6e-16 58.5 14.9 6e-16 58.1 14.9 1.0 1 0 0 1 1 1 1 Amino acid permease MARVEL PF01284.23 KRZ98296.1 - 0.00018 21.6 0.2 0.00032 20.8 0.2 1.4 1 1 0 1 1 1 1 Membrane-associating domain Phe_hydrox_dim PF07976.12 KRZ98298.1 - 2e-42 145.0 0.0 3.6e-42 144.2 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain FAD_binding_3 PF01494.19 KRZ98298.1 - 5e-08 32.6 0.0 7.3e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Zn_clus PF00172.18 KRZ98300.1 - 9.9e-09 35.2 8.1 1.6e-08 34.5 8.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Condensation PF00668.20 KRZ98300.1 - 0.027 13.1 0.3 0.086 11.5 0.2 1.7 2 0 0 2 2 2 0 Condensation domain SKN1 PF03935.15 KRZ98301.1 - 1.3e-69 234.9 0.1 1.9e-69 234.4 0.1 1.2 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) SKN1 PF03935.15 KRZ98302.1 - 2e-62 211.2 0.8 2.2e-62 211.1 0.8 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Arginase PF00491.21 KRZ98303.1 - 1e-87 294.2 0.0 1.3e-87 293.8 0.0 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 KRZ98303.1 - 0.036 14.3 0.2 0.058 13.6 0.2 1.5 1 0 0 1 1 1 0 UPF0489 domain SKN1 PF03935.15 KRZ98304.1 - 5.9e-20 71.1 0.0 8.5e-20 70.6 0.0 1.2 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) DUF4006 PF13179.6 KRZ98304.1 - 0.14 12.1 1.7 0.16 11.9 0.1 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF4006) DUF3112 PF11309.8 KRZ98305.1 - 0.026 14.0 1.4 0.035 13.6 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3112) DUF3112 PF11309.8 KRZ98306.1 - 9.8e-56 188.6 0.2 1.1e-55 188.4 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3112) DUF373 PF04123.13 KRZ98306.1 - 0.14 11.6 1.4 6.2 6.2 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF373) DUF3007 PF11460.8 KRZ98306.1 - 0.61 10.4 2.8 0.84 9.9 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3007) UDPGP PF01704.18 KRZ98307.1 - 1.5e-188 626.6 0.0 1.8e-188 626.4 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Glyco_hydro_3 PF00933.21 KRZ98308.1 - 4.2e-06 26.4 0.0 4.8e-06 26.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Requiem_N PF14051.6 KRZ98308.1 - 0.13 12.5 0.0 0.19 12.0 0.0 1.2 1 0 0 1 1 1 0 N-terminal domain of DPF2/REQ. LigB PF02900.18 KRZ98311.1 - 9.5e-19 67.5 0.0 1.1e-18 67.3 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase DUF5403 PF17395.2 KRZ98311.1 - 0.12 12.7 0.0 0.19 12.1 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5403) ABC_trans_N PF14510.6 KRZ98314.1 - 4.7e-21 75.2 0.0 6.1e-21 74.8 0.0 1.1 1 0 0 1 1 1 1 ABC-transporter N-terminal TauD PF02668.16 KRZ98315.1 - 2.6e-53 181.6 0.7 3.4e-53 181.2 0.7 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family SKN1 PF03935.15 KRZ98317.1 - 5.2e-110 368.2 0.1 6.4e-110 367.9 0.1 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) SKN1 PF03935.15 KRZ98318.1 - 3.9e-104 348.8 1.4 4.3e-104 348.7 1.4 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Cytomega_US3 PF05963.11 KRZ98318.1 - 0.14 11.8 0.3 3.9 7.1 0.1 2.1 2 0 0 2 2 2 0 Cytomegalovirus US3 protein OPT PF03169.15 KRZ98319.1 - 2.1e-132 442.9 27.5 2.5e-132 442.6 27.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein YtzH PF14165.6 KRZ98319.1 - 0.22 11.9 0.8 0.78 10.2 0.1 2.1 2 0 0 2 2 2 0 YtzH-like protein zf-C3HC PF07967.13 KRZ98320.1 - 4.6e-34 117.3 0.3 1.3e-32 112.6 0.2 2.5 2 0 0 2 2 2 1 C3HC zinc finger-like DUF402 PF04167.13 KRZ98320.1 - 0.011 15.9 0.1 0.031 14.5 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF402) Rsm1 PF08600.10 KRZ98320.1 - 0.064 13.4 5.6 2.3 8.4 0.0 3.9 4 1 0 4 4 4 0 Rsm1-like BIR PF00653.21 KRZ98320.1 - 0.39 11.4 4.3 0.93 10.2 0.1 2.8 3 0 0 3 3 3 0 Inhibitor of Apoptosis domain ABC_trans_N PF14510.6 KRZ98321.1 - 4.3e-23 81.7 1.1 5.2e-23 81.5 0.1 1.7 2 0 0 2 2 2 1 ABC-transporter N-terminal Sugar_tr PF00083.24 KRZ98323.1 - 6.2e-69 233.0 18.2 7.3e-69 232.8 18.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KRZ98323.1 - 5.4e-15 55.2 20.0 7.7e-15 54.7 20.0 1.2 1 1 0 1 1 1 1 Major Facilitator Superfamily Brix PF04427.18 KRZ98324.1 - 0.051 13.7 0.2 0.081 13.0 0.2 1.3 1 1 0 1 1 1 0 Brix domain DUF3698 PF12479.8 KRZ98326.1 - 1.4e-24 86.7 0.0 2.1e-23 82.9 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3698) EXS PF03124.14 KRZ98327.1 - 1.2e-40 139.8 10.1 1.5e-40 139.5 10.1 1.1 1 0 0 1 1 1 1 EXS family SPX PF03105.19 KRZ98328.1 - 2.1e-61 209.0 25.6 2.7e-61 208.6 25.6 1.1 1 0 0 1 1 1 1 SPX domain EXS PF03124.14 KRZ98328.1 - 6.6e-20 71.7 13.9 9.1e-20 71.2 13.9 1.2 1 0 0 1 1 1 1 EXS family VKOR PF07884.14 KRZ98328.1 - 0.83 9.9 5.3 2.4 8.3 0.2 2.2 2 0 0 2 2 2 0 Vitamin K epoxide reductase family Zn_clus PF00172.18 KRZ98329.1 - 1.2e-10 41.3 11.7 1.9e-10 40.7 11.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4637 PF15470.6 KRZ98329.1 - 1.6 8.4 9.6 3.1 7.5 9.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Fungal_trans PF04082.18 KRZ98330.1 - 1.3e-14 53.9 2.0 2.3e-14 53.1 2.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1963 PF09234.10 KRZ98332.1 - 2.4e-43 149.1 0.5 3e-43 148.8 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1963) RE_AspBHI_N PF18062.1 KRZ98332.1 - 0.015 14.9 0.1 0.022 14.3 0.1 1.3 1 0 0 1 1 1 0 Restriction endonuclease AspBHI N-terminal DUF1773 PF08593.10 KRZ98333.1 - 9.3e-13 49.0 0.0 1.5e-12 48.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function PPV_E1_C PF00519.17 KRZ98333.1 - 0.089 11.6 0.0 0.1 11.4 0.0 1.0 1 0 0 1 1 1 0 Papillomavirus helicase Arginase PF00491.21 KRZ98334.1 - 3.8e-38 131.6 0.0 4.7e-38 131.3 0.0 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 KRZ98334.1 - 0.059 13.6 0.1 0.1 12.9 0.1 1.3 1 0 0 1 1 1 0 UPF0489 domain AA_permease PF00324.21 KRZ98335.1 - 9.5e-107 357.5 40.3 1.1e-106 357.3 40.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KRZ98335.1 - 1.2e-26 93.5 41.8 1.5e-26 93.2 41.8 1.1 1 0 0 1 1 1 1 Amino acid permease DUF3360 PF11840.8 KRZ98336.1 - 0.13 10.9 0.0 0.18 10.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3360) MFS_1 PF07690.16 KRZ98337.1 - 2.9e-34 118.6 37.7 2.9e-34 118.6 37.7 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KRZ98337.1 - 9.7e-07 27.6 2.9 1.9e-06 26.6 2.9 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) FPN1 PF06963.12 KRZ98337.1 - 0.00056 18.6 0.5 0.001 17.7 0.5 1.3 1 0 0 1 1 1 1 Ferroportin1 (FPN1) Myc_target_1 PF15179.6 KRZ98337.1 - 0.81 9.6 2.7 1.7 8.5 0.7 2.2 2 0 0 2 2 2 0 Myc target protein 1 ADH_N PF08240.12 KRZ98338.1 - 1.2e-26 92.7 0.1 1.8e-26 92.1 0.1 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KRZ98338.1 - 2.9e-19 69.3 0.0 4.5e-19 68.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KRZ98338.1 - 2.1e-08 35.3 0.0 4.5e-08 34.2 0.0 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KRZ98338.1 - 0.00012 21.5 0.0 0.00019 20.8 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Glu_dehyd_C PF16912.5 KRZ98338.1 - 0.0019 17.7 0.0 0.0026 17.3 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus 2-Hacid_dh_C PF02826.19 KRZ98338.1 - 0.0032 16.8 0.0 0.0055 16.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_11 PF08241.12 KRZ98338.1 - 0.0061 17.2 0.0 0.011 16.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Shikimate_DH PF01488.20 KRZ98338.1 - 0.015 15.3 0.0 0.024 14.7 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 KRZ98338.1 - 0.032 13.5 0.1 0.046 13.0 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.18 KRZ98338.1 - 0.044 13.7 0.0 0.076 12.9 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_31 PF13847.6 KRZ98338.1 - 0.08 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain ThiF PF00899.21 KRZ98338.1 - 0.1 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 ThiF family RRN3 PF05327.11 KRZ98339.1 - 4e-183 610.0 9.0 4e-183 610.0 9.0 1.8 1 1 1 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 Clenterotox PF03505.14 KRZ98339.1 - 0.0089 15.7 1.2 3.9 7.0 0.1 2.5 2 0 0 2 2 2 2 Clostridium enterotoxin TFIIA PF03153.13 KRZ98339.1 - 7.7 6.4 17.5 3 7.7 1.0 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit CagX PF03524.15 KRZ98340.1 - 0.043 13.5 0.1 0.65 9.7 0.0 2.1 1 1 0 2 2 2 0 Conjugal transfer protein FAA_hydrolase PF01557.18 KRZ98341.1 - 2.3e-63 213.8 0.0 3.3e-63 213.3 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Oxidored_FMN PF00724.20 KRZ98343.1 - 5.6e-13 48.9 0.0 5.9e-13 48.8 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Oxidored_FMN PF00724.20 KRZ98344.1 - 4.9e-50 170.7 0.0 6.7e-49 167.0 0.0 1.9 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Ycf15 PF10705.9 KRZ98344.1 - 0.081 13.1 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Chloroplast protein precursor Ycf15 putative MFS_1 PF07690.16 KRZ98345.1 - 1.8e-12 46.9 71.9 5.8e-11 41.9 65.0 3.4 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2976 PF11190.8 KRZ98345.1 - 0.028 14.2 9.0 0.074 12.9 0.6 4.2 3 1 1 4 4 4 0 Protein of unknown function (DUF2976) Mannosyl_trans3 PF11051.8 KRZ98346.1 - 3.8e-88 295.4 0.2 1.2e-87 293.8 0.0 1.9 2 0 0 2 2 2 1 Mannosyltransferase putative Fungal_trans PF04082.18 KRZ98347.1 - 1.5e-29 102.9 1.4 3.7e-29 101.6 1.4 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KRZ98347.1 - 4.2e-09 36.4 10.3 8.5e-09 35.4 10.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.22 KRZ98348.1 - 5.2e-47 160.6 0.4 7.1e-47 160.2 0.4 1.0 1 0 0 1 1 1 1 Cytochrome P450 PurK_C PF17769.1 KRZ98348.1 - 0.051 13.3 0.1 6.8 6.5 0.1 2.8 2 0 0 2 2 2 0 Phosphoribosylaminoimidazole carboxylase C-terminal domain Fungal_trans_2 PF11951.8 KRZ98349.1 - 1.9e-62 211.3 2.9 2.2e-62 211.1 2.9 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Alpha-mann_mid PF09261.11 KRZ98349.1 - 0.011 15.8 0.6 3.5 7.8 0.1 2.9 3 0 0 3 3 3 0 Alpha mannosidase middle domain TIR_3 PF18567.1 KRZ98349.1 - 0.28 11.2 2.8 0.79 9.7 2.5 2.1 1 1 0 1 1 1 0 Toll/interleukin-1 receptor domain Peptidase_M16 PF00675.20 KRZ98350.1 - 1.9e-25 89.6 0.0 6e-25 88.0 0.0 1.9 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_M PF16187.5 KRZ98350.1 - 1.5e-22 80.2 1.2 3.3e-22 79.1 0.2 2.1 2 0 0 2 2 2 1 Middle or third domain of peptidase_M16 Peptidase_M16_C PF05193.21 KRZ98350.1 - 4.5e-07 30.1 1.6 0.00017 21.6 0.2 2.8 3 0 0 3 3 3 2 Peptidase M16 inactive domain Fcf2 PF08698.11 KRZ98351.1 - 1.8e-33 114.8 0.9 1.8e-33 114.8 0.9 1.8 2 0 0 2 2 2 1 Fcf2 pre-rRNA processing STD1 PF17235.2 KRZ98352.1 - 3.2e-63 213.1 10.2 3.2e-63 213.1 10.2 1.8 1 1 1 2 2 2 1 STD1/MTH1 NUP214 PF16755.5 KRZ98353.1 - 3.4e-26 92.4 0.0 5.7e-26 91.6 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 SdiA-regulated PF06977.11 KRZ98353.1 - 0.018 14.3 0.1 0.58 9.3 0.0 2.3 2 0 0 2 2 2 0 SdiA-regulated Crystall_2 PF09076.10 KRZ98353.1 - 0.028 14.3 0.1 0.085 12.7 0.1 1.9 1 0 0 1 1 1 0 Beta/Gamma crystallin PMG PF05287.12 KRZ98353.1 - 1.2 9.2 22.1 7.5 6.5 9.9 2.4 1 1 1 2 2 2 0 PMG protein CN_hydrolase PF00795.22 KRZ98354.1 - 2.1e-45 155.1 0.0 2.4e-45 154.9 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NmrA PF05368.13 KRZ98355.1 - 1e-08 35.1 0.0 2.1e-08 34.0 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 KRZ98355.1 - 0.00048 20.4 0.1 0.028 14.7 0.0 2.5 3 0 0 3 3 3 1 Saccharopine dehydrogenase NADP binding domain Malic_M PF03949.15 KRZ98356.1 - 2.8e-85 285.7 0.1 3.7e-85 285.3 0.1 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 KRZ98356.1 - 1e-61 207.9 0.0 1.7e-61 207.2 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain DUF2470 PF10615.9 KRZ98357.1 - 2e-13 50.8 0.0 2.8e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) DUF4499 PF14934.6 KRZ98357.1 - 0.032 14.6 0.1 0.081 13.3 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4499) Spindle_Spc25 PF08234.12 KRZ98358.1 - 7e-20 71.0 1.0 7e-19 67.8 0.0 2.5 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 DUF4201 PF13870.6 KRZ98358.1 - 0.00031 20.5 16.8 0.0005 19.8 16.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) JIP_LZII PF16471.5 KRZ98358.1 - 0.002 18.3 12.6 0.11 12.7 2.4 2.8 2 1 0 2 2 2 2 JNK-interacting protein leucine zipper II KASH_CCD PF14662.6 KRZ98358.1 - 0.0029 17.5 17.7 0.0041 17.0 17.7 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH Spc7 PF08317.11 KRZ98358.1 - 0.0063 15.4 12.7 0.0085 15.0 12.7 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein Nup54 PF13874.6 KRZ98358.1 - 0.013 15.6 6.6 0.021 14.9 6.6 1.4 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 DUF4200 PF13863.6 KRZ98358.1 - 0.016 15.6 22.1 0.016 15.6 19.9 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) DUF3450 PF11932.8 KRZ98358.1 - 0.018 14.3 13.8 0.029 13.7 13.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Uds1 PF15456.6 KRZ98358.1 - 0.036 14.2 10.6 0.13 12.4 10.4 2.0 1 1 0 1 1 1 0 Up-regulated During Septation Golgin_A5 PF09787.9 KRZ98358.1 - 0.042 13.3 15.8 0.052 13.0 15.8 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 HALZ PF02183.18 KRZ98358.1 - 0.05 13.8 5.6 0.05 13.8 5.6 3.9 4 0 0 4 4 3 0 Homeobox associated leucine zipper Cauli_AT PF03233.13 KRZ98358.1 - 0.077 12.9 13.3 0.96 9.4 0.0 2.8 1 1 2 3 3 3 0 Aphid transmission protein DUF713 PF05218.14 KRZ98358.1 - 0.086 12.6 10.2 0.051 13.3 6.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF713) Baculo_F PF12259.8 KRZ98358.1 - 0.1 11.1 7.7 0.13 10.7 7.7 1.3 1 0 0 1 1 1 0 Baculovirus F protein She9_MDM33 PF05546.11 KRZ98358.1 - 0.15 11.8 10.1 0.23 11.2 10.1 1.2 1 0 0 1 1 1 0 She9 / Mdm33 family V_ATPase_I PF01496.19 KRZ98358.1 - 0.27 9.1 5.3 0.35 8.7 5.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Zwint PF15556.6 KRZ98358.1 - 0.27 10.7 13.9 0.49 9.9 13.9 1.4 1 1 0 1 1 1 0 ZW10 interactor Baculo_PEP_C PF04513.12 KRZ98358.1 - 0.32 11.0 18.1 2.2 8.3 13.3 2.6 2 1 1 3 3 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ZapB PF06005.12 KRZ98358.1 - 0.38 11.2 20.6 0.15 12.5 8.8 2.8 2 1 1 3 3 2 0 Cell division protein ZapB DUF3086 PF11285.8 KRZ98358.1 - 0.4 9.7 9.4 1.7 7.7 1.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3086) LPP PF04728.13 KRZ98358.1 - 0.48 10.9 10.8 3.6 8.0 1.0 3.1 1 1 1 2 2 2 0 Lipoprotein leucine-zipper DivIC PF04977.15 KRZ98358.1 - 0.48 10.2 18.6 0.7 9.7 7.4 2.7 1 1 2 3 3 3 0 Septum formation initiator TraF_2 PF13729.6 KRZ98358.1 - 0.59 9.5 12.3 0.14 11.5 2.9 2.1 1 1 0 2 2 2 0 F plasmid transfer operon, TraF, protein DUF724 PF05266.14 KRZ98358.1 - 0.81 9.5 10.3 1.1 9.0 10.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Muted PF14942.6 KRZ98358.1 - 1.2 9.4 14.9 3 8.2 12.8 2.1 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein DUF1664 PF07889.12 KRZ98358.1 - 1.4 9.0 13.8 0.79 9.8 1.7 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) APG6_N PF17675.1 KRZ98358.1 - 2 9.0 18.9 0.62 10.6 15.4 1.8 1 1 0 1 1 1 0 Apg6 coiled-coil region Prominin PF05478.11 KRZ98358.1 - 2.2 6.2 13.0 4.8 5.0 13.0 1.5 1 1 0 1 1 1 0 Prominin DUF948 PF06103.11 KRZ98358.1 - 2.6 8.3 10.5 5.7 7.3 0.9 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) YabA PF06156.13 KRZ98358.1 - 3.1 8.5 13.7 4.9 7.9 7.8 2.5 1 1 1 2 2 2 0 Initiation control protein YabA DUF848 PF05852.11 KRZ98358.1 - 4.6 7.3 13.1 12 6.0 12.8 1.8 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) DUF1640 PF07798.11 KRZ98358.1 - 4.8 7.2 17.4 68 3.4 16.9 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) bZIP_1 PF00170.21 KRZ98358.1 - 5.9 7.1 17.1 6.2 7.0 1.6 3.1 2 1 1 3 3 2 0 bZIP transcription factor GrpE PF01025.19 KRZ98358.1 - 8.5 6.0 14.7 4.6 6.9 4.3 2.3 1 1 1 2 2 2 0 GrpE Lectin_N PF03954.14 KRZ98358.1 - 8.6 6.1 12.3 6.4 6.5 8.6 2.4 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain Exo_endo_phos PF03372.23 KRZ98359.1 - 2.9e-12 46.6 0.0 4.2e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family INSIG PF07281.12 KRZ98359.1 - 0.063 12.9 0.1 0.095 12.3 0.1 1.2 1 0 0 1 1 1 0 Insulin-induced protein (INSIG) Promethin PF16015.5 KRZ98359.1 - 1.7 8.6 4.4 2.8 7.9 4.4 1.3 1 0 0 1 1 1 0 Promethin Phos_pyr_kin PF08543.12 KRZ98360.1 - 6.1e-16 58.5 0.0 8.1e-16 58.1 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 KRZ98360.1 - 1.9e-06 27.4 0.0 3.3e-06 26.6 0.0 1.3 1 1 0 1 1 1 1 pfkB family carbohydrate kinase DUF1198 PF06711.11 KRZ98360.1 - 0.14 12.3 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1198) bZIP_2 PF07716.15 KRZ98361.1 - 1.6e-06 28.1 8.9 1.6e-06 28.1 8.9 2.0 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 KRZ98361.1 - 2.2e-06 27.7 8.4 2.5e-06 27.5 6.7 2.1 1 1 1 2 2 2 1 bZIP transcription factor PH_18 PF18469.1 KRZ98361.1 - 0.073 13.0 1.2 0.14 12.1 0.1 1.9 2 0 0 2 2 2 0 Pleckstrin homology domain bZIP_Maf PF03131.17 KRZ98361.1 - 0.28 11.7 10.3 0.1 13.1 7.3 1.8 2 1 0 2 2 2 0 bZIP Maf transcription factor tRNA_Me_trans PF03054.16 KRZ98362.1 - 1.7e-105 352.8 0.0 1.8e-105 352.6 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase zf-C2H2 PF00096.26 KRZ98363.1 - 9.7e-05 22.6 20.9 0.00023 21.4 3.1 4.1 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KRZ98363.1 - 0.0011 19.3 3.8 0.0011 19.3 3.8 2.8 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KRZ98363.1 - 0.0046 17.7 2.0 0.0046 17.7 2.0 3.4 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KRZ98363.1 - 0.018 15.1 0.6 0.07 13.2 0.6 2.1 1 0 0 1 1 1 0 C2H2-type zinc finger zf-met PF12874.7 KRZ98363.1 - 0.036 14.5 1.9 0.036 14.5 1.9 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type YusW PF14039.6 KRZ98363.1 - 0.14 12.7 2.2 0.28 11.7 1.0 2.2 2 0 0 2 2 2 0 YusW-like protein TERB2 PF15101.6 KRZ98363.1 - 2.1 8.4 30.0 2.5 8.1 5.1 2.4 2 0 0 2 2 2 0 Telomere-associated protein TERB2 zf-C2HE PF16278.5 KRZ98363.1 - 3.7 8.1 11.0 4.6 7.8 3.0 4.2 3 1 1 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger DOCK_N PF16172.5 KRZ98364.1 - 2e-11 43.4 0.4 5.6e-07 28.8 0.2 2.7 2 1 0 2 2 2 2 DOCK N-terminus DHDPS PF00701.22 KRZ98365.1 - 1.1e-34 119.5 0.0 1.4e-34 119.1 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Fungal_trans PF04082.18 KRZ98366.1 - 1.3e-23 83.4 5.7 2.3e-23 82.6 5.7 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.18 KRZ98367.1 - 7.6e-08 31.7 1.6 7.6e-08 31.7 1.6 2.0 2 1 0 2 2 2 1 Fungal specific transcription factor domain Ldi PF18566.1 KRZ98368.1 - 0.013 15.0 0.0 0.014 14.9 0.0 1.0 1 0 0 1 1 1 0 Linalool dehydratase/isomerase MIP PF00230.20 KRZ98369.1 - 4.6e-41 141.0 13.0 6.2e-41 140.6 13.0 1.1 1 0 0 1 1 1 1 Major intrinsic protein YesK PF14150.6 KRZ98369.1 - 0.0093 16.1 1.3 0.0093 16.1 1.3 2.0 2 0 0 2 2 2 1 YesK-like protein MFS_1 PF07690.16 KRZ98371.1 - 3.6e-17 62.3 17.0 3.6e-17 62.3 17.0 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily FAD_binding_3 PF01494.19 KRZ98372.1 - 1e-21 77.6 0.0 1.2e-21 77.4 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KRZ98372.1 - 0.00033 20.8 0.0 0.00058 20.0 0.0 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KRZ98372.1 - 0.00037 19.3 0.0 0.00049 18.9 0.0 1.1 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 KRZ98372.1 - 0.00056 19.2 0.0 0.00075 18.8 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 KRZ98372.1 - 0.0012 18.2 0.0 0.0018 17.6 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KRZ98372.1 - 0.0041 16.4 0.0 0.0058 15.9 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KRZ98372.1 - 0.0068 16.0 0.0 0.0086 15.7 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KRZ98372.1 - 0.013 16.0 0.0 0.022 15.3 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KRZ98372.1 - 0.022 13.8 0.0 0.029 13.4 0.0 1.1 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 KRZ98372.1 - 0.026 13.6 0.0 0.034 13.2 0.0 1.1 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.22 KRZ98372.1 - 0.057 12.5 0.0 0.091 11.8 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 KRZ98372.1 - 0.1 12.6 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding baeRF_family5 PF18846.1 KRZ98372.1 - 0.11 12.7 0.1 0.18 12.0 0.1 1.3 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 5 ApbA PF02558.16 KRZ98372.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Aldedh PF00171.22 KRZ98373.1 - 2e-123 412.3 0.2 2.4e-123 412.1 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Helicase_IV_N PF12462.8 KRZ98373.1 - 0.05 13.6 0.0 0.26 11.2 0.0 2.0 2 0 0 2 2 2 0 DNA helicase IV / RNA helicase N terminal DUF2229 PF09989.9 KRZ98373.1 - 0.15 11.7 0.1 0.63 9.7 0.0 1.9 2 0 0 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) DUF3698 PF12479.8 KRZ98374.1 - 1.5e-43 147.7 0.0 1.7e-40 137.9 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF3698) Pkinase PF00069.25 KRZ98374.1 - 9.7e-05 21.9 0.0 0.00017 21.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KRZ98374.1 - 0.015 15.2 0.0 0.025 14.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ferritin_2 PF13668.6 KRZ98376.1 - 1.5e-39 135.3 1.1 2.2e-39 134.8 1.1 1.3 1 0 0 1 1 1 1 Ferritin-like domain Peptidase_M1 PF01433.20 KRZ98377.1 - 3.7e-43 147.6 0.1 5.9e-43 147.0 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 KRZ98377.1 - 7.1e-32 109.8 0.0 1.7e-31 108.6 0.0 1.7 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M48 PF01435.18 KRZ98377.1 - 0.13 12.0 0.0 0.22 11.3 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M48 Peptidase_M61 PF05299.12 KRZ98377.1 - 0.46 10.9 2.5 14 6.1 2.5 2.6 1 1 0 1 1 1 0 M61 glycyl aminopeptidase BAG PF02179.16 KRZ98378.1 - 6e-23 81.1 1.0 6e-23 81.1 1.0 2.0 2 0 0 2 2 2 1 BAG domain COG5 PF10392.9 KRZ98378.1 - 0.0029 17.8 0.5 0.12 12.5 0.0 2.3 2 0 0 2 2 2 1 Golgi transport complex subunit 5 PDE4_UCR PF18100.1 KRZ98378.1 - 0.0041 17.8 0.9 0.12 13.0 0.1 2.4 2 1 0 2 2 2 1 Phosphodiesterase 4 upstream conserved regions (UCR) Cytochrom_C550 PF14495.6 KRZ98378.1 - 0.05 13.3 0.7 7.6 6.2 0.0 2.3 2 1 0 2 2 2 0 Cytochrome c-550 domain 7TM_GPCR_Srx PF10328.9 KRZ98378.1 - 0.081 12.5 0.1 0.1 12.2 0.1 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx ApoO PF09769.9 KRZ98378.1 - 0.12 12.3 0.5 0.23 11.4 0.0 1.7 2 0 0 2 2 2 0 Apolipoprotein O Glu-tRNAGln PF02686.15 KRZ98378.1 - 0.16 12.3 1.2 15 6.0 0.0 3.1 2 1 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit Rep_Org_C PF06926.11 KRZ98378.1 - 0.22 11.8 3.1 0.49 10.7 1.3 2.2 2 0 0 2 2 2 0 Putative replisome organiser protein C-terminus Mt_ATP-synt_D PF05873.12 KRZ98378.1 - 2.5 7.9 8.9 12 5.7 5.5 3.0 1 1 1 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) Tmemb_170 PF10190.9 KRZ98381.1 - 0.014 15.7 0.2 0.048 14.0 0.0 1.9 2 0 0 2 2 2 0 Putative transmembrane protein 170 Barwin PF00967.17 KRZ98381.1 - 0.072 12.9 0.1 0.1 12.4 0.1 1.2 1 0 0 1 1 1 0 Barwin family Lact_bio_phlase PF09508.10 KRZ98382.1 - 0.19 10.1 0.0 0.2 10.1 0.0 1.1 1 0 0 1 1 1 0 Lacto-N-biose phosphorylase N-terminal TIM barrel domain AA_permease PF00324.21 KRZ98383.1 - 3.7e-118 395.2 41.6 4.3e-118 394.9 41.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KRZ98383.1 - 3.9e-36 124.8 47.2 4.8e-36 124.5 47.2 1.1 1 0 0 1 1 1 1 Amino acid permease DUF2845 PF11006.8 KRZ98383.1 - 0.078 13.1 0.3 0.57 10.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2845) PrgI PF12666.7 KRZ98383.1 - 0.087 13.5 0.0 0.087 13.5 0.0 4.2 4 1 0 4 4 4 0 PrgI family protein Peptidase_M18 PF02127.15 KRZ98384.1 - 1.5e-168 561.1 0.0 1.7e-168 560.9 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 KRZ98384.1 - 0.0001 21.4 0.0 0.059 12.4 0.0 2.3 1 1 0 2 2 2 2 M42 glutamyl aminopeptidase DUF4763 PF15960.5 KRZ98384.1 - 0.14 11.5 0.6 0.2 10.9 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) CAP PF00188.26 KRZ98385.1 - 1.4e-13 51.7 9.5 4.4e-13 50.2 9.5 1.7 1 1 0 1 1 1 1 Cysteine-rich secretory protein family tRNA-synt_2d PF01409.20 KRZ98386.1 - 1.4e-24 86.9 0.2 2e-24 86.4 0.2 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) Flavodoxin_1 PF00258.25 KRZ98387.1 - 4.6e-28 98.2 0.0 7.8e-28 97.5 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.20 KRZ98387.1 - 6.8e-22 78.1 0.0 1.5e-21 77.0 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 KRZ98387.1 - 3.7e-14 53.3 0.0 6.7e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_3 PF12641.7 KRZ98387.1 - 0.019 14.6 0.0 0.044 13.5 0.0 1.6 2 0 0 2 2 2 0 Flavodoxin domain Bromodomain PF00439.25 KRZ98388.1 - 1.4e-25 89.2 2.1 5.8e-14 51.9 0.1 2.7 2 0 0 2 2 2 2 Bromodomain Sas10_Utp3 PF04000.15 KRZ98388.1 - 7.9 7.2 10.5 1.2 9.8 0.2 3.3 3 0 0 3 3 3 0 Sas10/Utp3/C1D family GFA PF04828.14 KRZ98389.1 - 1.6e-10 41.1 0.1 2.2e-10 40.7 0.1 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme SUKH_5 PF14567.6 KRZ98389.1 - 0.13 12.0 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 SMI1-KNR4 cell-wall FAD_binding_3 PF01494.19 KRZ98390.1 - 2.2e-29 102.8 0.0 2.9e-29 102.4 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KRZ98390.1 - 8.6e-08 31.8 1.8 0.00074 18.8 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KRZ98390.1 - 6e-07 29.4 4.2 0.00015 21.4 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 KRZ98390.1 - 9.6e-05 22.9 0.5 0.024 15.2 0.2 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KRZ98390.1 - 0.00021 20.5 1.8 0.00021 20.5 1.8 1.6 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KRZ98390.1 - 0.00098 17.9 3.3 0.044 12.5 0.8 2.2 2 0 0 2 2 2 2 HI0933-like protein FAD_oxidored PF12831.7 KRZ98390.1 - 0.0013 18.1 1.2 0.0028 17.1 1.2 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 KRZ98390.1 - 0.0032 16.8 2.7 0.7 9.1 0.8 2.6 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase Trp_halogenase PF04820.14 KRZ98390.1 - 0.0034 16.3 1.7 0.11 11.4 0.1 2.5 2 1 1 3 3 3 1 Tryptophan halogenase NAD_binding_8 PF13450.6 KRZ98390.1 - 0.0039 17.4 0.3 0.015 15.5 0.3 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KRZ98390.1 - 0.2 10.7 4.4 0.065 12.3 0.6 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KRZ98390.1 - 1.6 7.9 8.7 0.6 9.3 2.4 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.16 KRZ98391.1 - 7.2e-28 97.5 25.1 8.8e-28 97.2 25.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3601 PF12208.8 KRZ98391.1 - 0.082 13.0 0.8 2.5 8.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3601) Cu-oxidase_2 PF07731.14 KRZ98392.1 - 5.5e-48 162.2 6.3 5.2e-43 146.1 0.8 3.6 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KRZ98392.1 - 3.6e-44 149.6 4.6 1.1e-41 141.6 0.5 3.4 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 KRZ98392.1 - 3.9e-37 127.8 4.4 2.8e-32 112.0 0.4 3.5 3 0 0 3 3 3 3 Multicopper oxidase Fibritin_C PF07921.12 KRZ98392.1 - 0.012 15.8 0.0 0.037 14.2 0.0 1.8 2 0 0 2 2 2 0 Fibritin C-terminal region adh_short_C2 PF13561.6 KRZ98393.1 - 9.6e-41 139.9 0.1 1.2e-40 139.6 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KRZ98393.1 - 5.6e-39 133.6 0.0 7.5e-39 133.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KRZ98393.1 - 9.3e-09 35.4 0.1 1.4e-08 34.8 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KRZ98393.1 - 0.00012 21.7 0.1 0.00024 20.6 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KRZ98393.1 - 0.0033 16.6 0.0 0.0046 16.1 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KRZ98393.1 - 0.011 15.2 0.1 1.1 8.6 0.1 2.1 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase DUF4253 PF14062.6 KRZ98393.1 - 0.048 13.8 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4253) FMN_dh PF01070.18 KRZ98394.1 - 5.5e-115 384.1 0.0 7.6e-115 383.7 0.0 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KRZ98394.1 - 1.4e-20 73.2 0.0 3.6e-20 71.9 0.0 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 KRZ98394.1 - 1.6e-08 34.1 0.1 2.5e-08 33.5 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KRZ98394.1 - 6.7e-05 22.0 0.0 0.00011 21.3 0.0 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 KRZ98394.1 - 0.00028 20.4 0.0 0.00048 19.6 0.0 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.21 KRZ98394.1 - 0.043 13.3 0.3 0.81 9.1 0.1 2.4 1 1 0 2 2 2 0 Histidine biosynthesis protein ThiG PF05690.14 KRZ98394.1 - 0.19 11.0 0.0 6 6.1 0.0 2.2 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG Fungal_trans PF04082.18 KRZ98395.1 - 2.9e-22 79.0 5.6 4.1e-22 78.5 5.6 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain RdDM_RDM1 PF09187.10 KRZ98396.1 - 0.079 13.0 0.1 0.13 12.3 0.1 1.3 1 0 0 1 1 1 0 RNA-directed DNA methylation 1 TENA_THI-4 PF03070.16 KRZ98397.1 - 2.4e-10 40.6 0.2 6.4e-10 39.2 0.2 1.6 1 1 0 1 1 1 1 TENA/THI-4/PQQC family Transp_cyt_pur PF02133.15 KRZ98398.1 - 1.9e-17 63.2 36.2 5.6e-17 61.6 36.2 1.6 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin S_4TM PF18159.1 KRZ98398.1 - 0.25 10.6 0.1 0.25 10.6 0.1 3.1 4 0 0 4 4 4 0 SMODS-associating 4TM effector domain Melibiase_2 PF16499.5 KRZ98399.1 - 7.5e-54 182.8 5.4 1.6e-53 181.7 5.4 1.5 1 1 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 KRZ98399.1 - 9.4e-09 35.2 0.0 1.8e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 KRZ98399.1 - 0.0017 17.4 0.1 0.0069 15.4 0.0 1.8 2 0 0 2 2 2 1 Melibiase DUF3612 PF12268.8 KRZ98400.1 - 0.066 13.3 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3612) Mid2 PF04478.12 KRZ98401.1 - 2e-10 40.7 1.3 2e-10 40.7 1.3 2.2 2 1 1 3 3 3 1 Mid2 like cell wall stress sensor DUF4448 PF14610.6 KRZ98401.1 - 6.7e-05 22.8 1.2 8.3e-05 22.4 0.4 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF4448) Amnionless PF14828.6 KRZ98401.1 - 0.00012 21.1 0.6 0.00017 20.6 0.6 1.2 1 0 0 1 1 1 1 Amnionless LAP1C PF05609.12 KRZ98401.1 - 0.00087 18.5 6.1 0.0011 18.1 6.1 1.1 1 0 0 1 1 1 1 Lamina-associated polypeptide 1C (LAP1C) DAG1 PF05454.11 KRZ98401.1 - 0.11 11.8 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Syndecan PF01034.20 KRZ98401.1 - 1.7 8.6 3.6 0.57 10.1 0.7 1.6 2 0 0 2 2 2 0 Syndecan domain TrbL PF04610.14 KRZ98401.1 - 6.3 6.5 7.9 0.63 9.7 2.1 2.1 2 1 0 2 2 2 0 TrbL/VirB6 plasmid conjugal transfer protein SKG6 PF08693.10 KRZ98401.1 - 9.2 5.8 16.0 0.061 12.7 6.2 2.7 2 1 0 2 2 2 0 Transmembrane alpha-helix domain Pkinase PF00069.25 KRZ98402.1 - 7.5e-08 32.0 0.1 8.8e-08 31.8 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KRZ98402.1 - 6.7e-05 22.3 0.0 8.8e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 KRZ98402.1 - 0.026 13.8 0.0 0.035 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Choline_kinase PF01633.20 KRZ98402.1 - 0.037 13.6 0.0 0.063 12.9 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.23 KRZ98402.1 - 0.2 11.6 0.0 0.26 11.2 0.0 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family DIOX_N PF14226.6 KRZ98403.1 - 4.3e-14 53.3 0.1 9.2e-14 52.2 0.1 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KRZ98403.1 - 3.8e-13 49.8 0.1 7.3e-13 48.9 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily AA_permease PF00324.21 KRZ98404.1 - 8e-105 351.2 53.0 9.8e-105 350.9 53.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KRZ98404.1 - 5.6e-33 114.4 57.8 7.3e-33 114.0 57.8 1.0 1 0 0 1 1 1 1 Amino acid permease Ca_bind_SSO6904 PF18249.1 KRZ98406.1 - 0.0022 18.3 0.5 0.0045 17.3 0.5 1.5 1 0 0 1 1 1 1 Calcium binding protein SSO6904 Carbpep_Y_N PF05388.11 KRZ98406.1 - 0.01 16.4 0.7 0.019 15.5 0.3 1.5 1 1 1 2 2 2 0 Carboxypeptidase Y pro-peptide Abhydrolase_6 PF12697.7 KRZ98407.1 - 2.8e-10 41.2 0.2 3.4e-10 40.9 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KRZ98407.1 - 0.0019 17.5 0.0 0.0029 16.9 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 KRZ98407.1 - 0.0058 16.3 0.0 0.0085 15.8 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.20 KRZ98407.1 - 0.0079 15.9 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold SRP_TPR_like PF17004.5 KRZ98408.1 - 0.0042 17.1 0.3 0.011 15.7 0.3 1.7 1 0 0 1 1 1 1 Putative TPR-like repeat HLH PF00010.26 KRZ98408.1 - 0.017 15.0 0.0 0.053 13.5 0.0 1.9 1 1 0 1 1 1 0 Helix-loop-helix DNA-binding domain LAMTOR PF15454.6 KRZ98409.1 - 7.1e-12 45.8 2.9 1.5e-11 44.7 2.9 1.5 1 1 0 1 1 1 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator DUF5561 PF17716.1 KRZ98409.1 - 0.078 12.3 4.5 1.8 7.8 2.1 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5561) AMMECR1 PF01871.17 KRZ98410.1 - 1.2e-37 129.1 0.0 1.7e-37 128.6 0.0 1.2 1 0 0 1 1 1 1 AMMECR1 CTP_transf_1 PF01148.20 KRZ98411.1 - 7.4e-05 22.6 2.2 0.00014 21.7 2.2 1.5 1 1 0 1 1 1 1 Cytidylyltransferase family Lipase_3 PF01764.25 KRZ98412.1 - 1.4e-30 106.0 0.2 1.7e-29 102.5 0.2 2.2 1 1 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 KRZ98412.1 - 0.00041 20.0 0.0 0.012 15.2 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) Hydrolase_4 PF12146.8 KRZ98412.1 - 0.096 11.9 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Fungal_trans PF04082.18 KRZ98413.1 - 4.9e-18 65.1 1.8 4.9e-18 65.1 1.8 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain TPR_1 PF00515.28 KRZ98414.1 - 9.5e-46 151.8 24.0 7.4e-07 28.7 0.1 9.6 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_2 PF07719.17 KRZ98414.1 - 6e-36 119.7 24.8 2.2e-05 24.2 0.0 9.4 9 0 0 9 9 9 8 Tetratricopeptide repeat STI1 PF17830.1 KRZ98414.1 - 8.3e-32 108.9 13.6 4.4e-17 61.8 4.7 3.2 3 0 0 3 3 2 2 STI1 domain TPR_8 PF13181.6 KRZ98414.1 - 2.3e-20 71.1 25.7 5.4e-06 26.2 0.1 8.9 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_11 PF13414.6 KRZ98414.1 - 2.5e-20 71.9 20.1 0.00034 20.2 0.0 7.8 7 1 1 8 8 8 5 TPR repeat TPR_12 PF13424.6 KRZ98414.1 - 6e-19 68.1 12.2 3.3e-09 36.9 0.8 5.9 4 2 2 6 6 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 KRZ98414.1 - 5e-18 64.2 5.9 0.049 14.5 0.0 8.3 4 3 4 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 KRZ98414.1 - 5.1e-18 65.4 5.1 0.00018 22.1 0.0 5.9 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 KRZ98414.1 - 1.7e-14 54.0 15.1 0.0053 17.2 0.3 6.5 3 3 3 6 6 6 5 Tetratricopeptide repeat TPR_7 PF13176.6 KRZ98414.1 - 9.2e-14 50.4 10.7 0.024 14.7 0.0 7.7 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_17 PF13431.6 KRZ98414.1 - 3.5e-13 48.9 15.0 0.8 10.2 0.3 7.8 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_9 PF13371.6 KRZ98414.1 - 1.2e-09 38.2 1.1 0.00039 20.5 0.0 5.0 5 1 1 6 6 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 KRZ98414.1 - 3e-09 36.5 9.1 0.95 9.4 0.0 6.9 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_6 PF13174.6 KRZ98414.1 - 0.00016 22.1 21.2 15 6.4 0.1 8.3 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_MalT PF17874.1 KRZ98414.1 - 0.00057 19.3 1.0 0.011 15.1 0.9 2.4 2 1 0 2 2 2 1 MalT-like TPR region Fis1_TPR_C PF14853.6 KRZ98414.1 - 0.0006 19.8 4.5 3 8.0 0.0 5.3 6 0 0 6 6 5 1 Fis1 C-terminal tetratricopeptide repeat SHNi-TPR PF10516.9 KRZ98414.1 - 0.0046 16.4 5.6 19 4.8 0.0 5.2 5 0 0 5 5 5 0 SHNi-TPR DUF3808 PF10300.9 KRZ98414.1 - 0.02 13.7 0.6 0.14 10.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3808) Inhibitor_I9 PF05922.16 KRZ98414.1 - 0.041 14.6 0.1 0.26 12.0 0.1 2.4 1 0 0 1 1 1 0 Peptidase inhibitor I9 ANAPC3 PF12895.7 KRZ98414.1 - 0.13 12.5 15.6 0.8 10.0 0.7 4.7 2 1 3 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF3856 PF12968.7 KRZ98414.1 - 0.16 12.0 10.3 13 5.8 0.1 5.3 3 3 1 4 4 4 0 Domain of Unknown Function (DUF3856) SPO22 PF08631.10 KRZ98414.1 - 0.78 9.2 6.8 6.1 6.2 0.0 3.8 3 1 1 4 4 4 0 Meiosis protein SPO22/ZIP4 like TPR_20 PF14561.6 KRZ98414.1 - 1.8 9.0 9.7 9.5 6.6 0.1 4.5 3 1 1 4 4 4 0 Tetratricopeptide repeat MIT PF04212.18 KRZ98414.1 - 3 8.0 17.3 2.8 8.1 0.3 6.0 6 1 0 6 6 5 0 MIT (microtubule interacting and transport) domain MAS20 PF02064.15 KRZ98414.1 - 3.9 7.6 7.3 8.1 6.5 0.0 3.8 2 1 1 3 3 3 0 MAS20 protein import receptor Alkyl_sulf_dimr PF14863.6 KRZ98414.1 - 4.3 7.8 6.9 5.3 7.5 0.1 3.9 2 2 3 5 5 5 0 Alkyl sulfatase dimerisation bZIP_1 PF00170.21 KRZ98415.1 - 1.7e-05 24.8 15.5 4.7e-05 23.4 15.5 1.8 1 0 0 1 1 1 1 bZIP transcription factor HMMR_N PF15905.5 KRZ98415.1 - 0.0017 17.9 16.4 0.0032 17.0 16.4 1.3 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal bZIP_Maf PF03131.17 KRZ98415.1 - 0.1 13.1 11.6 0.095 13.2 10.1 1.7 1 1 0 1 1 1 0 bZIP Maf transcription factor bZIP_2 PF07716.15 KRZ98415.1 - 0.31 11.1 18.3 0.34 11.0 16.6 2.0 2 0 0 2 2 2 0 Basic region leucine zipper FYVE_2 PF02318.16 KRZ98415.1 - 0.4 10.9 4.1 0.76 10.0 4.1 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger NARP1 PF12569.8 KRZ98416.1 - 5.1e-126 421.6 23.1 2.2e-96 323.8 3.9 3.8 3 2 1 4 4 4 3 NMDA receptor-regulated protein 1 TPR_2 PF07719.17 KRZ98416.1 - 1.7e-20 71.4 20.3 0.0025 17.8 0.1 9.3 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_16 PF13432.6 KRZ98416.1 - 2.2e-15 57.0 0.9 0.00053 20.6 0.0 6.6 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 KRZ98416.1 - 9.7e-12 45.2 6.0 0.052 14.1 0.0 7.2 5 3 2 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 KRZ98416.1 - 4.9e-11 42.5 4.7 0.16 12.8 0.0 7.5 5 3 3 8 8 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 KRZ98416.1 - 5.7e-11 42.6 13.3 0.013 15.8 0.8 7.2 6 3 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 KRZ98416.1 - 2.2e-10 39.9 16.5 0.033 14.0 0.0 8.6 9 1 0 9 9 9 2 Tetratricopeptide repeat TPR_8 PF13181.6 KRZ98416.1 - 3.2e-10 39.4 23.7 0.0015 18.6 0.0 8.2 9 0 0 9 9 7 4 Tetratricopeptide repeat TPR_17 PF13431.6 KRZ98416.1 - 1.4e-09 37.7 1.2 0.1 13.0 0.0 5.7 5 0 0 5 5 4 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KRZ98416.1 - 8.9e-09 35.5 18.6 0.0027 17.9 1.8 6.0 3 1 3 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 KRZ98416.1 - 3.6e-06 26.7 9.2 4.7 7.2 0.0 7.0 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 KRZ98416.1 - 0.0006 19.7 13.0 1.6 8.9 0.1 8.3 9 1 0 9 9 8 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KRZ98416.1 - 0.0014 18.1 1.2 1.4 8.2 0.1 2.8 2 1 1 3 3 3 2 MalT-like TPR region TPR_9 PF13371.6 KRZ98416.1 - 0.0023 18.1 0.0 0.4 10.9 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat Rapsyn_N PF10579.9 KRZ98416.1 - 0.0053 16.8 0.1 0.02 15.0 0.1 2.0 1 0 0 1 1 1 1 Rapsyn N-terminal myristoylation and linker region Fis1_TPR_C PF14853.6 KRZ98416.1 - 0.028 14.5 7.9 4.2 7.5 0.2 4.6 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_4 PF07721.14 KRZ98416.1 - 0.039 14.6 0.0 9.1 7.2 0.0 3.6 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 KRZ98416.1 - 0.051 13.3 8.8 4.5 7.0 0.1 6.2 5 2 1 6 6 6 0 TPR repeat TPR_6 PF13174.6 KRZ98416.1 - 0.38 11.5 6.3 9.9 7.0 0.1 6.0 8 0 0 8 8 5 0 Tetratricopeptide repeat Sel1 PF08238.12 KRZ98416.1 - 1.1 10.1 8.5 24 5.8 0.3 4.9 5 0 0 5 5 5 0 Sel1 repeat Fungal_trans PF04082.18 KRZ98417.1 - 9.5e-16 57.6 1.8 9.5e-16 57.6 1.8 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KRZ98417.1 - 1.5e-08 34.6 11.4 3.9e-08 33.3 11.4 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 KRZ98418.1 - 1.7e-10 40.9 12.8 2.7e-10 40.2 12.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribonuc_P_40 PF08584.11 KRZ98418.1 - 0.25 10.6 3.8 0.29 10.4 3.8 1.1 1 0 0 1 1 1 0 Ribonuclease P 40kDa (Rpp40) subunit V_ATPase_I PF01496.19 KRZ98418.1 - 0.83 7.5 5.3 0.84 7.5 5.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DNA_pol_phi PF04931.13 KRZ98418.1 - 1.2 7.1 10.7 1.4 6.9 10.7 1.2 1 0 0 1 1 1 0 DNA polymerase phi Astro_capsid_p PF12226.8 KRZ98418.1 - 1.4 8.0 8.6 1.9 7.6 8.6 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein DUF4637 PF15470.6 KRZ98418.1 - 2.1 8.0 15.8 0.2 11.4 10.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) ParBc PF02195.18 KRZ98419.1 - 2.5e-15 56.5 0.0 3.1e-15 56.2 0.0 1.1 1 0 0 1 1 1 1 ParB-like nuclease domain FAD_binding_8 PF08022.12 KRZ98420.1 - 3.7e-21 75.2 0.1 7.9e-21 74.2 0.1 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 KRZ98420.1 - 6.2e-20 71.6 12.8 6.2e-20 71.6 12.8 2.9 3 0 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KRZ98420.1 - 9.8e-18 64.8 0.0 1.7e-17 64.0 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain zf-CCHC PF00098.23 KRZ98421.1 - 2.9e-06 27.1 0.6 5.1e-06 26.3 0.6 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 KRZ98421.1 - 0.024 14.6 0.9 0.048 13.6 0.9 1.5 1 0 0 1 1 1 0 Zinc knuckle Retrotrans_gag PF03732.17 KRZ98421.1 - 0.046 14.0 0.1 0.096 13.0 0.1 1.4 1 0 0 1 1 1 0 Retrotransposon gag protein eIF3g PF12353.8 KRZ98421.1 - 0.73 10.2 4.2 0.28 11.6 1.2 1.9 2 1 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G Thiolase_N PF00108.23 KRZ98422.1 - 1.1e-69 234.7 0.3 1.5e-69 234.3 0.3 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KRZ98422.1 - 3.4e-41 139.7 0.5 1.6e-40 137.5 0.1 2.2 3 0 0 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KRZ98422.1 - 0.00021 21.0 0.2 0.0004 20.0 0.2 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KRZ98422.1 - 0.044 13.6 0.3 11 6.0 0.1 2.5 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III CTP_transf_1 PF01148.20 KRZ98423.1 - 0.0081 15.9 6.3 0.033 13.9 6.5 1.7 1 1 0 1 1 1 1 Cytidylyltransferase family ParA PF10609.9 KRZ98424.1 - 4.7e-99 330.8 0.5 5.5e-99 330.6 0.5 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KRZ98424.1 - 3.4e-12 46.5 0.0 5.7e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 KRZ98424.1 - 7.1e-10 39.1 2.4 1.1e-07 31.9 0.5 2.2 2 0 0 2 2 2 2 AAA domain MipZ PF09140.11 KRZ98424.1 - 1.2e-07 31.4 0.0 1.8e-07 30.7 0.0 1.3 1 1 0 1 1 1 1 ATPase MipZ Fer4_NifH PF00142.18 KRZ98424.1 - 5e-07 29.4 1.8 1e-05 25.1 1.8 2.2 1 1 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ArsA_ATPase PF02374.15 KRZ98424.1 - 0.00012 21.4 3.5 0.00046 19.5 1.0 2.3 2 1 0 2 2 2 1 Anion-transporting ATPase AAA_26 PF13500.6 KRZ98424.1 - 0.0012 18.7 1.3 0.6 9.9 0.0 2.2 2 0 0 2 2 2 2 AAA domain CBP_BcsQ PF06564.12 KRZ98424.1 - 0.0045 16.5 0.7 0.12 11.8 0.2 2.1 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ zf-ZPR1 PF03367.13 KRZ98424.1 - 0.024 14.5 0.0 0.046 13.6 0.0 1.4 1 0 0 1 1 1 0 ZPR1 zinc-finger domain Zn_Tnp_IS1595 PF12760.7 KRZ98424.1 - 0.16 11.9 0.1 0.31 11.0 0.1 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain VirC1 PF07015.11 KRZ98424.1 - 0.17 11.1 0.0 0.36 10.1 0.1 1.5 2 0 0 2 2 2 0 VirC1 protein MnmE_helical PF12631.7 KRZ98425.1 - 5.6e-41 141.0 1.6 7.3e-41 140.6 1.6 1.2 1 0 0 1 1 1 1 MnmE helical domain TrmE_N PF10396.9 KRZ98425.1 - 2.4e-24 85.9 0.0 5.8e-24 84.6 0.0 1.7 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.23 KRZ98425.1 - 8.7e-20 70.9 1.0 2.4e-19 69.5 0.3 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KRZ98425.1 - 4.7e-08 32.7 0.7 1e-07 31.6 0.7 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KRZ98425.1 - 2.2e-07 30.9 1.7 0.00067 19.6 0.2 2.3 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KRZ98425.1 - 7e-05 22.5 0.3 0.0024 17.4 0.1 2.5 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain Arf PF00025.21 KRZ98425.1 - 0.00015 21.3 1.1 0.11 11.9 0.0 2.6 3 0 0 3 3 3 2 ADP-ribosylation factor family AIG1 PF04548.16 KRZ98425.1 - 0.00027 20.3 0.1 0.00058 19.2 0.1 1.5 1 0 0 1 1 1 1 AIG1 family Ras PF00071.22 KRZ98425.1 - 0.00039 20.0 0.1 0.0021 17.7 0.0 2.2 2 1 0 2 2 2 1 Ras family Dynamin_N PF00350.23 KRZ98425.1 - 0.00066 19.8 0.4 0.0028 17.8 0.0 2.4 2 2 0 2 2 2 1 Dynamin family Gtr1_RagA PF04670.12 KRZ98425.1 - 0.0017 17.8 3.3 1.7 7.9 0.5 3.1 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 KRZ98425.1 - 0.013 15.7 0.0 0.1 12.8 0.0 2.4 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 KRZ98425.1 - 0.04 14.4 0.9 0.086 13.4 0.3 2.1 2 1 0 2 2 2 0 ABC transporter AAA_18 PF13238.6 KRZ98425.1 - 0.045 14.3 0.0 0.16 12.5 0.0 2.0 1 0 0 1 1 1 0 AAA domain PE PF00934.20 KRZ98425.1 - 0.067 13.5 0.0 0.17 12.2 0.0 1.7 1 0 0 1 1 1 0 PE family AAA_16 PF13191.6 KRZ98425.1 - 0.069 13.5 0.0 6.2 7.2 0.0 2.5 1 1 1 2 2 2 0 AAA ATPase domain PduV-EutP PF10662.9 KRZ98425.1 - 0.25 11.1 4.4 26 4.5 0.0 3.9 4 0 0 4 4 4 0 Ethanolamine utilisation - propanediol utilisation Asp PF00026.23 KRZ98426.1 - 1.7e-62 211.6 8.6 1.3e-52 179.2 7.1 2.0 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 KRZ98426.1 - 5.6e-11 43.0 2.9 4.3e-09 36.8 0.5 3.9 3 1 0 3 3 3 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KRZ98426.1 - 2.2e-08 34.6 0.3 0.22 12.2 0.0 3.6 3 0 0 3 3 3 3 Aspartyl protease gag-asp_proteas PF13975.6 KRZ98426.1 - 9.4e-07 29.3 0.0 0.8 10.3 0.0 4.2 3 1 0 3 3 3 2 gag-polyprotein putative aspartyl protease DHR-2 PF06920.13 KRZ98427.1 - 1.3e-39 136.2 1.2 2.2e-39 135.5 1.2 1.4 1 1 0 1 1 1 1 Dock homology region 2 Peptidase_C21 PF05381.12 KRZ98427.1 - 0.15 12.4 0.3 0.73 10.2 0.1 2.2 2 0 0 2 2 2 0 Tymovirus endopeptidase ThrE PF06738.12 KRZ98427.1 - 0.2 11.0 0.0 0.35 10.2 0.0 1.3 1 0 0 1 1 1 0 Putative threonine/serine exporter Aldolase_II PF00596.21 KRZ98428.1 - 2.8e-08 33.9 0.4 3.9e-08 33.4 0.1 1.4 2 0 0 2 2 2 1 Class II Aldolase and Adducin N-terminal domain Aminotran_3 PF00202.21 KRZ98430.1 - 3.1e-08 32.7 0.0 3.6e-08 32.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III GLF PF03275.13 KRZ98430.1 - 0.099 12.4 0.6 0.26 11.0 0.1 1.7 1 1 0 2 2 2 0 UDP-galactopyranose mutase Aminotran_3 PF00202.21 KRZ98431.1 - 0.00032 19.5 0.0 0.00032 19.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III FAD_binding_6 PF00970.24 KRZ98434.1 - 1.9e-09 37.8 0.0 3e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KRZ98434.1 - 2.2e-05 25.1 0.0 3e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 KRZ98434.1 - 0.026 14.7 0.0 0.044 13.9 0.0 1.4 1 0 0 1 1 1 0 Ferric reductase NAD binding domain Baculo_PEP_C PF04513.12 KRZ98436.1 - 0.0012 18.9 5.2 0.0048 16.9 0.8 2.3 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus Spidroin_MaSp PF11260.8 KRZ98436.1 - 0.082 13.2 1.0 9.8 6.6 0.1 2.6 2 1 0 2 2 2 0 Major ampullate spidroin 1 and 2 Syntaxin_2 PF14523.6 KRZ98436.1 - 1.4 9.4 18.0 8.9 6.7 0.7 3.1 2 1 0 2 2 2 0 Syntaxin-like protein zf-ZPR1 PF03367.13 KRZ98436.1 - 5.5 6.8 11.7 5.1 6.9 0.2 3.0 1 1 2 3 3 3 0 ZPR1 zinc-finger domain WD40 PF00400.32 KRZ98437.1 - 7.3e-19 67.8 22.9 0.0012 19.6 0.1 6.8 6 2 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KRZ98437.1 - 2.4e-06 27.8 6.3 0.061 13.6 0.1 4.0 2 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain PNP_UDP_1 PF01048.20 KRZ98438.1 - 8.5e-49 165.9 0.0 1e-48 165.6 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Ribosomal_S8e PF01201.22 KRZ98440.1 - 1.7e-55 187.0 2.2 2e-55 186.7 2.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e Ribosomal_L27_C PF18471.1 KRZ98442.1 - 2.4e-68 230.2 9.3 3e-68 229.8 9.3 1.1 1 0 0 1 1 1 1 Ribosomal L27 protein C-terminal domain Ribosomal_L27 PF01016.19 KRZ98442.1 - 7.2e-33 112.5 0.1 1.2e-32 111.8 0.1 1.3 1 0 0 1 1 1 1 Ribosomal L27 protein Rer1 PF03248.13 KRZ98443.1 - 2.5e-77 258.4 9.5 2.9e-77 258.2 9.5 1.0 1 0 0 1 1 1 1 Rer1 family DUF1538 PF07556.11 KRZ98443.1 - 1.6 8.0 5.3 1.3 8.2 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1538) DUF1449 PF07290.11 KRZ98443.1 - 1.7 8.2 4.4 13 5.4 4.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1449) ANTH PF07651.16 KRZ98444.1 - 3.1e-74 249.5 0.0 3.1e-74 249.5 0.0 3.5 2 1 0 3 3 3 1 ANTH domain I_LWEQ PF01608.17 KRZ98444.1 - 1.9e-52 177.5 6.9 1.9e-52 177.5 6.9 5.9 3 1 2 5 5 5 2 I/LWEQ domain TcdB_N PF12918.7 KRZ98444.1 - 0.0024 18.1 2.5 0.0024 18.1 2.5 4.1 3 2 2 5 5 5 1 TcdB toxin N-terminal helical domain SapB_1 PF05184.15 KRZ98444.1 - 0.12 12.4 2.0 0.34 11.0 0.2 2.9 2 0 0 2 2 2 0 Saposin-like type B, region 1 DUF730 PF05325.11 KRZ98444.1 - 0.51 10.4 6.0 0.24 11.4 0.3 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF730) PSII_Pbs27 PF13326.6 KRZ98444.1 - 1 9.7 8.8 0.25 11.7 1.4 3.3 3 1 0 3 3 3 0 Photosystem II Pbs27 FAA_hydro_N_2 PF18288.1 KRZ98444.1 - 1.1 9.8 7.0 1.2 9.6 1.6 3.8 3 1 1 4 4 4 0 Fumarylacetoacetase N-terminal domain 2 ADH_N PF08240.12 KRZ98445.1 - 2.9e-28 97.9 0.6 4.9e-28 97.2 0.6 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KRZ98445.1 - 2.4e-20 72.8 0.0 4.5e-20 72.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KRZ98445.1 - 4.2e-06 26.4 0.0 8.3e-06 25.4 0.0 1.5 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus Methyltransf_25 PF13649.6 KRZ98445.1 - 0.004 17.8 0.0 0.0079 16.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain 2-Hacid_dh_C PF02826.19 KRZ98445.1 - 0.02 14.3 0.0 0.032 13.6 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.6 KRZ98445.1 - 0.028 15.4 0.0 0.052 14.6 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KRZ98445.1 - 0.14 11.5 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Sec5 PF15469.6 KRZ98445.1 - 0.15 11.9 1.0 0.18 11.6 0.2 1.5 2 0 0 2 2 2 0 Exocyst complex component Sec5 Ribosomal_L22e PF01776.17 KRZ98447.1 - 0.61 10.5 5.8 0.79 10.1 0.1 3.2 3 0 0 3 3 3 0 Ribosomal L22e protein family DJ-1_PfpI PF01965.24 KRZ98448.1 - 4.7e-06 26.5 0.0 1.5e-05 24.9 0.0 1.7 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 KRZ98448.1 - 0.00073 19.3 0.3 0.0034 17.1 0.3 2.0 1 1 0 1 1 1 1 ThiJ/PfpI family-like NmrA PF05368.13 KRZ98449.1 - 0.016 14.8 0.0 0.02 14.4 0.0 1.1 1 0 0 1 1 1 0 NmrA-like family FAD_binding_4 PF01565.23 KRZ98450.1 - 1e-24 86.9 0.0 2.1e-24 85.8 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.19 KRZ98450.1 - 3.8e-08 33.3 0.0 5.4e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain RPE65 PF03055.15 KRZ98451.1 - 4.3e-90 303.1 0.0 4.9e-90 302.9 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein LRR_8 PF13855.6 KRZ98452.1 - 0.0014 18.4 62.8 0.14 11.9 7.5 7.8 5 1 3 8 8 8 5 Leucine rich repeat LRR_6 PF13516.6 KRZ98452.1 - 0.0023 17.8 47.9 0.0095 15.9 0.7 9.4 9 0 0 9 9 9 3 Leucine Rich repeat LRR_4 PF12799.7 KRZ98452.1 - 0.006 17.0 79.5 0.079 13.4 20.6 7.3 4 3 3 7 7 7 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KRZ98452.1 - 0.92 10.3 59.7 2.4 9.0 0.1 10.2 8 2 1 9 9 9 0 Leucine Rich Repeat Sugar_tr PF00083.24 KRZ98453.1 - 2.5e-101 339.8 20.8 2.9e-101 339.6 20.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KRZ98453.1 - 3.6e-19 68.9 27.0 3.6e-19 68.9 27.0 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Cyclin_N PF00134.23 KRZ98454.1 - 0.05 13.3 0.1 0.083 12.6 0.1 1.4 1 0 0 1 1 1 0 Cyclin, N-terminal domain Metallophos PF00149.28 KRZ98456.1 - 3.2e-13 50.7 2.0 4.6e-13 50.1 2.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KRZ98456.1 - 0.0071 16.6 0.2 0.015 15.5 0.2 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain G-alpha PF00503.20 KRZ98457.1 - 2.8e-109 365.5 9.4 3.5e-109 365.2 9.4 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KRZ98457.1 - 3.9e-14 52.5 0.8 1.3e-09 37.8 0.0 2.7 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KRZ98457.1 - 0.011 15.1 5.0 0.038 13.3 0.3 2.3 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region NB-ARC PF00931.22 KRZ98457.1 - 0.011 14.9 0.2 0.019 14.1 0.2 1.3 1 0 0 1 1 1 0 NB-ARC domain Roc PF08477.13 KRZ98457.1 - 0.037 14.2 0.3 5.4 7.3 0.1 2.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 KRZ98457.1 - 0.038 13.8 0.4 0.1 12.4 0.1 1.8 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 KRZ98457.1 - 0.077 12.5 0.1 0.92 9.0 0.0 2.5 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain ABC_membrane PF00664.23 KRZ98459.1 - 5e-55 187.1 49.6 1.8e-33 116.4 25.5 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KRZ98459.1 - 5.6e-47 159.7 0.8 6.9e-27 94.6 0.1 3.0 2 1 0 2 2 2 2 ABC transporter AAA_29 PF13555.6 KRZ98459.1 - 1.8e-07 30.8 1.0 0.00045 19.9 0.1 2.9 3 0 0 3 3 3 2 P-loop containing region of AAA domain SMC_N PF02463.19 KRZ98459.1 - 2.3e-07 30.5 13.9 0.00064 19.2 1.1 4.9 3 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KRZ98459.1 - 5.5e-05 23.1 8.5 1.5 8.6 0.1 4.9 3 2 1 5 5 5 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 KRZ98459.1 - 0.0015 19.1 0.8 0.95 10.0 0.0 3.2 3 0 0 3 3 2 1 AAA domain RsgA_GTPase PF03193.16 KRZ98459.1 - 0.0015 18.5 0.2 1.6 8.7 0.1 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 KRZ98459.1 - 0.0017 18.9 12.8 0.046 14.2 0.9 4.4 3 1 1 4 4 4 2 AAA domain AAA_30 PF13604.6 KRZ98459.1 - 0.0034 17.1 0.4 0.31 10.7 0.1 2.6 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.23 KRZ98459.1 - 0.0036 17.4 3.1 0.75 9.9 0.1 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 KRZ98459.1 - 0.005 17.2 0.0 0.29 11.5 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain FtsK_SpoIIIE PF01580.18 KRZ98459.1 - 0.11 11.8 0.4 3.6 6.9 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family MeaB PF03308.16 KRZ98459.1 - 0.13 11.2 0.8 6.6 5.6 0.4 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 KRZ98459.1 - 0.15 12.4 5.6 11 6.3 1.1 3.4 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KRZ98459.1 - 0.19 11.0 2.0 13 5.0 0.0 2.7 3 0 0 3 3 3 0 Zeta toxin ATP_bind_1 PF03029.17 KRZ98459.1 - 0.37 10.5 2.6 26 4.5 0.4 3.1 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein DUF87 PF01935.17 KRZ98459.1 - 3 7.9 6.1 2.5 8.1 0.0 3.1 3 0 0 3 3 3 0 Helicase HerA, central domain SKN1 PF03935.15 KRZ98460.1 - 2.4e-92 310.0 3.8 2.6e-92 309.8 3.8 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Glyco_hydro_3_C PF01915.22 KRZ98461.1 - 2.3e-61 207.3 0.0 4.3e-61 206.4 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KRZ98461.1 - 1.9e-41 142.5 0.0 3e-41 141.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KRZ98461.1 - 1.1e-21 76.7 0.1 2.5e-21 75.6 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 KRZ98461.1 - 7e-16 58.4 0.1 1.5e-15 57.3 0.1 1.5 1 0 0 1 1 1 1 PA14 domain MFS_1 PF07690.16 KRZ98462.1 - 4.1e-30 104.9 24.1 4.1e-30 104.9 24.1 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF2304 PF10066.9 KRZ98462.1 - 0.12 12.6 0.0 0.12 12.6 0.0 3.8 4 1 1 5 5 5 0 Uncharacterized conserved protein (DUF2304) TraL PF07178.11 KRZ98462.1 - 1.5 9.4 6.0 0.36 11.3 0.3 2.8 3 0 0 3 3 3 0 TraL protein CENP-L PF13092.6 KRZ98463.1 - 0.15 12.3 0.0 0.17 12.1 0.0 1.1 1 0 0 1 1 1 0 Kinetochore complex Sim4 subunit Fta1 AA_permease_2 PF13520.6 KRZ98464.1 - 3.9e-66 223.7 46.2 4.8e-66 223.3 46.2 1.1 1 0 0 1 1 1 1 Amino acid permease Aminotran_1_2 PF00155.21 KRZ98465.1 - 5.8e-26 91.5 0.0 7.3e-26 91.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 KRZ98465.1 - 0.014 14.2 0.0 0.029 13.1 0.0 1.5 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase RIO1 PF01163.22 KRZ98466.1 - 2.8e-67 226.0 2.6 2.8e-67 226.0 2.6 1.4 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 KRZ98466.1 - 0.0029 17.6 0.1 0.53 10.2 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kei1 PF08552.11 KRZ98467.1 - 6.3e-44 150.1 2.9 1.1e-43 149.4 2.9 1.4 1 1 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 DUF1129 PF06570.11 KRZ98467.1 - 0.015 14.8 0.1 0.038 13.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) CitMHS PF03600.16 KRZ98467.1 - 0.054 12.7 0.1 0.069 12.3 0.1 1.2 1 0 0 1 1 1 0 Citrate transporter PepSY_TM_like_2 PF16357.5 KRZ98467.1 - 0.056 13.4 0.1 0.093 12.7 0.1 1.3 1 0 0 1 1 1 0 Putative PepSY_TM-like TLD PF07534.16 KRZ98468.1 - 7.3e-27 94.3 1.5 4.9e-24 85.1 1.4 2.6 1 1 1 2 2 2 2 TLD ThiF PF00899.21 KRZ98469.1 - 8e-58 195.7 0.0 1.1e-57 195.3 0.0 1.1 1 0 0 1 1 1 1 ThiF family UAE_UbL PF14732.6 KRZ98469.1 - 3e-08 34.1 1.4 3e-08 34.1 1.4 3.0 3 0 0 3 3 3 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.9 KRZ98469.1 - 1.2e-07 32.0 19.4 0.00018 21.5 0.8 3.3 2 1 1 3 3 3 2 Ubiquitin-activating enzyme active site MTBP_N PF14918.6 KRZ98469.1 - 0.012 15.1 0.9 0.024 14.1 0.9 1.4 1 0 0 1 1 1 0 MDM2-binding FYDLN_acid PF09538.10 KRZ98469.1 - 2.8 8.7 6.0 1.7 9.4 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Glycos_transf_2 PF00535.26 KRZ98470.1 - 2.1e-08 34.2 0.0 2.6e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KRZ98470.1 - 0.0027 17.2 0.0 0.0045 16.5 0.0 1.3 1 1 0 1 1 1 1 Glycosyl transferase family 21 Fungal_trans PF04082.18 KRZ98471.1 - 9e-59 198.7 4.1 9e-59 198.7 4.1 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KRZ98471.1 - 2.9e-07 30.6 10.5 0.0011 19.3 3.2 3.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KRZ98471.1 - 0.0004 20.7 3.1 0.0004 20.7 3.1 2.9 3 0 0 3 3 3 1 Zinc-finger double domain FOXP-CC PF16159.5 KRZ98471.1 - 0.002 18.7 5.3 0.18 12.5 0.7 2.8 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-C2H2_aberr PF17017.5 KRZ98471.1 - 0.0042 17.2 0.9 1.7 8.8 0.1 2.8 1 1 1 2 2 2 2 Aberrant zinc-finger zf-C2H2_4 PF13894.6 KRZ98471.1 - 0.0049 17.6 8.6 0.68 10.9 1.6 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KRZ98471.1 - 0.013 15.5 5.0 0.31 11.1 1.3 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger DUF3454 PF11936.8 KRZ98471.1 - 0.12 12.8 4.3 1.3 9.5 0.8 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3454) FANCL_C PF11793.8 KRZ98471.1 - 0.12 12.6 2.8 5.5 7.2 1.8 2.9 2 0 0 2 2 2 0 FANCL C-terminal domain Sugar_tr PF00083.24 KRZ98472.1 - 1.7e-96 323.9 24.7 1.9e-96 323.7 24.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KRZ98472.1 - 2.2e-26 92.6 28.1 1.2e-24 86.9 19.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Xpo1 PF08389.12 KRZ98473.1 - 1.6e-32 112.6 4.0 1.6e-32 112.6 4.0 4.8 4 0 0 4 4 4 3 Exportin 1-like protein PALP PF00291.25 KRZ98474.1 - 1.1e-71 241.7 0.0 1.3e-71 241.5 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme tRNA_int_endo PF01974.17 KRZ98475.1 - 1e-10 41.5 0.0 1.8e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 KRZ98475.1 - 0.007 16.0 0.1 0.023 14.3 0.1 1.9 1 1 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain Myb_DNA-binding PF00249.31 KRZ98476.1 - 1.6e-25 89.0 2.2 5.1e-13 49.0 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KRZ98476.1 - 3.3e-19 68.9 1.2 1.3e-12 47.8 0.0 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 KRZ98476.1 - 0.0068 16.4 0.0 0.043 13.9 0.0 2.1 1 1 1 2 2 2 1 SLIDE Rap1_C PF11626.8 KRZ98476.1 - 0.031 14.4 0.0 0.07 13.2 0.0 1.6 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Sigma70_r4_2 PF08281.12 KRZ98476.1 - 0.1 12.3 0.0 0.68 9.6 0.0 2.1 2 0 0 2 2 2 0 Sigma-70, region 4 zf-CSL PF05207.13 KRZ98477.1 - 2.8e-21 75.0 0.3 3.7e-21 74.6 0.3 1.2 1 0 0 1 1 1 1 CSL zinc finger Prok-RING_1 PF14446.6 KRZ98477.1 - 0.16 11.9 2.1 0.31 11.0 2.1 1.5 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 PTPlike_phytase PF14566.6 KRZ98477.1 - 0.17 12.0 0.1 0.2 11.8 0.1 1.1 1 0 0 1 1 1 0 Inositol hexakisphosphate DUF1773 PF08593.10 KRZ98478.1 - 2.6e-13 50.8 0.0 4.1e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF2415 PF10313.9 KRZ98481.1 - 1e-20 73.3 0.5 2e-20 72.5 0.5 1.5 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) ANAPC4_WD40 PF12894.7 KRZ98481.1 - 0.0088 16.3 0.0 0.044 14.1 0.0 2.2 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 KRZ98481.1 - 0.18 10.1 0.0 0.6 8.4 0.0 1.8 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz WD40 PF00400.32 KRZ98481.1 - 0.37 11.7 0.1 0.37 11.7 0.1 4.4 6 0 0 6 6 6 0 WD domain, G-beta repeat CDC45 PF02724.14 KRZ98482.1 - 1.2e-213 711.0 2.8 1.4e-213 710.8 2.8 1.0 1 0 0 1 1 1 1 CDC45-like protein YL1 PF05764.13 KRZ98482.1 - 0.027 14.6 20.5 0.15 12.1 17.1 2.1 2 0 0 2 2 2 0 YL1 nuclear protein Nop53 PF07767.11 KRZ98482.1 - 0.24 10.8 17.8 0.41 10.0 17.8 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) BUD22 PF09073.10 KRZ98482.1 - 1.1 8.6 15.3 0.027 13.8 8.9 1.5 2 0 0 2 2 2 0 BUD22 Nop14 PF04147.12 KRZ98482.1 - 3 5.9 21.4 0.046 11.9 13.9 1.6 2 0 0 2 2 2 0 Nop14-like family AAA_11 PF13086.6 KRZ98482.1 - 4.3 7.1 8.2 1.5 8.5 5.5 1.6 2 0 0 2 2 2 0 AAA domain ZZ PF00569.17 KRZ98483.1 - 1.9e-10 40.4 4.4 5.3e-10 38.9 4.4 1.8 1 0 0 1 1 1 1 Zinc finger, ZZ type Ribosomal_60s PF00428.19 KRZ98483.1 - 0.0053 17.3 9.0 0.016 15.8 9.0 1.8 1 0 0 1 1 1 1 60s Acidic ribosomal protein Band_3_cyto PF07565.13 KRZ98483.1 - 0.99 9.2 10.2 0.073 12.9 1.7 2.8 3 0 0 3 3 3 0 Band 3 cytoplasmic domain Acid_PPase PF12689.7 KRZ98484.1 - 1.5e-40 138.8 0.0 1.7e-40 138.6 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase HAD_SAK_2 PF18143.1 KRZ98484.1 - 0.0039 17.5 0.0 0.0044 17.3 0.0 1.1 1 0 0 1 1 1 1 HAD domain in Swiss Army Knife RNA repair proteins RVT_2 PF07727.14 KRZ98484.1 - 0.027 14.1 0.1 0.033 13.8 0.1 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Ish1 PF10281.9 KRZ98485.1 - 0.061 13.6 0.9 0.15 12.4 0.9 1.6 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein Histone_H2A_C PF16211.5 KRZ98486.1 - 2.7e-21 75.0 2.1 4.5e-21 74.3 2.1 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KRZ98486.1 - 5e-17 62.5 0.0 6.5e-17 62.1 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KRZ98486.1 - 8.6e-06 25.9 0.0 1.2e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KRZ98487.1 - 2e-20 73.5 3.1 2.5e-20 73.2 3.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KRZ98487.1 - 2.6e-07 30.8 0.1 5.9e-07 29.7 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone YscO-like PF16789.5 KRZ98487.1 - 0.0027 17.8 0.4 0.0033 17.5 0.4 1.1 1 0 0 1 1 1 1 YscO-like protein TFIID_20kDa PF03847.13 KRZ98487.1 - 0.0054 17.2 0.0 0.0094 16.4 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CENP-W PF15510.6 KRZ98487.1 - 0.049 13.9 0.0 0.072 13.3 0.0 1.3 1 0 0 1 1 1 0 CENP-W protein Fungal_trans PF04082.18 KRZ98488.1 - 4.7e-30 104.5 1.4 1.1e-29 103.3 1.4 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KRZ98488.1 - 2.5e-08 33.9 9.5 5.2e-08 32.9 9.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KRZ98489.1 - 1.5e-32 112.9 24.7 1.5e-32 112.9 24.7 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1689 PF07954.11 KRZ98489.1 - 0.55 10.6 1.8 0.69 10.3 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1689) FAD_binding_3 PF01494.19 KRZ98490.1 - 1.1e-24 87.4 0.0 1.3e-24 87.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KRZ98490.1 - 2.5e-08 33.5 0.5 8.4e-05 21.9 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KRZ98490.1 - 3.7e-06 26.8 3.4 0.063 12.9 2.8 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KRZ98490.1 - 1.5e-05 24.1 1.5 0.016 14.1 0.0 2.9 2 1 0 3 3 3 2 Tryptophan halogenase Amino_oxidase PF01593.24 KRZ98490.1 - 2.2e-05 23.9 0.4 0.16 11.2 0.1 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 KRZ98490.1 - 3.3e-05 23.2 2.2 5.4e-05 22.4 2.2 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 KRZ98490.1 - 4.2e-05 24.0 0.9 0.0032 18.0 0.2 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KRZ98490.1 - 0.00032 20.2 0.7 0.00062 19.2 0.7 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KRZ98490.1 - 0.00059 20.0 1.0 0.0015 18.7 1.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KRZ98490.1 - 0.00083 18.2 3.1 0.0098 14.6 0.9 2.1 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.12 KRZ98490.1 - 0.0026 16.9 2.3 0.036 13.1 2.3 2.0 1 1 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KRZ98490.1 - 0.0036 16.6 6.6 0.06 12.6 3.0 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KRZ98490.1 - 0.69 8.9 6.7 0.059 12.4 1.7 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A Phosphodiest PF01663.22 KRZ98491.1 - 2e-12 47.4 2.9 4.9e-11 42.8 2.9 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 KRZ98491.1 - 2e-05 24.1 0.0 3.9e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 KRZ98491.1 - 0.0022 17.4 0.0 0.0035 16.8 0.0 1.3 1 0 0 1 1 1 1 Sulfatase zf-C2H2_2 PF12756.7 KRZ98492.1 - 3.9e-34 117.0 4.6 3.1e-31 107.7 2.2 3.0 3 0 0 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 KRZ98492.1 - 0.0086 16.5 0.2 0.0086 16.5 0.2 3.1 3 1 0 3 3 3 1 Zinc finger, C2H2 type PP_kinase_C PF13090.6 KRZ98492.1 - 0.013 15.0 0.2 0.026 14.0 0.2 1.5 1 0 0 1 1 1 0 Polyphosphate kinase C-terminal domain 2 zf-C2H2_jaz PF12171.8 KRZ98492.1 - 0.019 15.2 2.1 0.019 15.2 0.1 2.1 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding RuvB_C PF05491.13 KRZ98492.1 - 0.032 14.1 0.0 0.072 13.0 0.0 1.6 1 0 0 1 1 1 0 RuvB C-terminal winged helix domain DUF5017 PF16409.5 KRZ98492.1 - 0.033 13.7 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5017) DUF2024 PF09630.10 KRZ98492.1 - 0.1 12.5 0.1 0.3 11.0 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF2024) zf-C2H2_4 PF13894.6 KRZ98492.1 - 0.37 11.7 0.1 0.37 11.7 0.1 3.1 3 1 0 3 3 3 0 C2H2-type zinc finger Presenilin PF01080.17 KRZ98492.1 - 0.58 8.9 3.8 0.99 8.1 3.8 1.3 1 0 0 1 1 1 0 Presenilin AAA_11 PF13086.6 KRZ98492.1 - 0.59 9.9 10.3 1.1 8.9 10.3 1.4 1 0 0 1 1 1 0 AAA domain DNA_pol_A_exo1 PF01612.20 KRZ98493.1 - 9.5e-46 155.7 0.8 3.4e-45 153.9 0.1 2.1 2 0 0 2 2 2 1 3'-5' exonuclease PMC2NT PF08066.12 KRZ98493.1 - 1.5e-18 67.3 1.6 1.5e-18 67.3 1.6 3.2 2 0 0 2 2 2 1 PMC2NT (NUC016) domain HRDC PF00570.23 KRZ98493.1 - 5.3e-09 35.9 0.0 1.3e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 HRDC domain AGO_N PF18236.1 KRZ98493.1 - 0.062 13.5 0.7 0.27 11.5 0.7 2.1 1 0 0 1 1 1 0 Argonaute N domain TPR_MLP1_2 PF07926.12 KRZ98495.1 - 2.2e-20 73.0 20.2 2.2e-20 73.0 20.2 19.4 6 5 12 20 20 20 6 TPR/MLP1/MLP2-like protein kleA_kleC PF17383.2 KRZ98495.1 - 7.4 7.0 16.5 1.3 9.4 0.2 6.1 4 1 0 4 4 4 0 Uncharacterized KorC regulated protein A Aminotran_1_2 PF00155.21 KRZ98496.1 - 1.3e-52 179.1 0.0 1.5e-52 179.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II zf-C2H2 PF00096.26 KRZ98497.1 - 5.1e-08 33.0 11.8 3.7e-05 23.9 1.1 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KRZ98497.1 - 7.3e-07 29.5 9.0 0.016 16.0 0.2 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KRZ98497.1 - 1.9e-05 24.9 3.0 1.9e-05 24.9 3.0 3.8 4 0 0 4 4 4 1 Zinc-finger double domain zf-met PF12874.7 KRZ98497.1 - 2.4e-05 24.6 2.1 0.015 15.6 0.7 2.9 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KRZ98497.1 - 0.0017 18.6 4.2 0.058 13.7 0.9 2.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KRZ98497.1 - 0.19 11.8 10.5 0.045 13.8 1.1 3.0 2 1 0 2 2 2 0 C2H2-type zinc finger Ogr_Delta PF04606.12 KRZ98497.1 - 0.27 11.3 1.2 1.1 9.3 1.2 2.1 1 1 0 1 1 1 0 Ogr/Delta-like zinc finger zf-C2H2_2 PF12756.7 KRZ98497.1 - 1.1 9.6 10.1 2 8.8 1.5 3.1 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) ARS2 PF04959.13 KRZ98497.1 - 2.2 8.6 7.3 0.25 11.7 1.9 2.2 1 1 1 2 2 2 0 Arsenite-resistance protein 2 Ldh_1_C PF02866.18 KRZ98498.1 - 4.4e-49 166.6 0.5 8.9e-49 165.6 0.2 1.6 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 KRZ98498.1 - 4.4e-45 153.3 0.0 7.3e-45 152.5 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KRZ98498.1 - 0.0016 17.5 0.0 0.0037 16.3 0.0 1.7 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sugar_tr PF00083.24 KRZ98499.1 - 6e-37 127.6 23.9 2.2e-36 125.7 23.9 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KRZ98499.1 - 2.2e-34 118.9 35.8 2.9e-29 102.1 19.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Presenilin PF01080.17 KRZ98499.1 - 0.063 12.0 1.5 0.12 11.1 1.5 1.4 1 0 0 1 1 1 0 Presenilin TRI12 PF06609.13 KRZ98499.1 - 0.076 11.4 11.6 0.33 9.3 2.6 2.1 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) Pkinase PF00069.25 KRZ98500.1 - 1.3e-06 28.0 0.0 1.9e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KRZ98500.1 - 0.00011 21.7 0.0 0.00015 21.2 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KRZ98500.1 - 0.0067 16.4 0.0 0.0095 15.9 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KRZ98500.1 - 0.02 14.2 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase PI3_PI4_kinase PF00454.27 KRZ98500.1 - 0.089 12.6 0.1 2.3 7.9 0.0 2.1 2 0 0 2 2 2 0 Phosphatidylinositol 3- and 4-kinase UbiA PF01040.18 KRZ98502.1 - 4.1e-49 167.2 11.5 7.4e-49 166.3 11.5 1.3 1 0 0 1 1 1 1 UbiA prenyltransferase family MitMem_reg PF13012.6 KRZ98503.1 - 1.6e-33 115.5 0.6 4.3e-33 114.1 0.6 1.7 1 1 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 KRZ98503.1 - 1.4e-30 105.7 0.0 2.5e-30 104.9 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease ATP_bind_1 PF03029.17 KRZ98504.1 - 7.8e-68 228.8 0.3 1.1e-67 228.3 0.3 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein TBCA PF02970.16 KRZ98505.1 - 3.3e-25 88.2 13.0 3.8e-25 88.0 13.0 1.0 1 0 0 1 1 1 1 Tubulin binding cofactor A WHEP-TRS PF00458.20 KRZ98505.1 - 0.0034 17.5 0.4 0.0092 16.1 0.4 1.7 1 0 0 1 1 1 1 WHEP-TRS domain TubC_N PF18563.1 KRZ98505.1 - 0.027 14.5 0.1 0.072 13.1 0.1 1.7 1 0 0 1 1 1 0 TubC N-terminal docking domain HTH_Tnp_Tc3_1 PF11427.8 KRZ98505.1 - 0.069 13.0 0.1 0.12 12.2 0.1 1.5 1 1 0 1 1 1 0 Tc3 transposase FapA PF03961.13 KRZ98505.1 - 0.2 10.2 9.0 0.23 10.0 9.0 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A KIP1 PF07765.12 KRZ98505.1 - 0.57 10.3 6.4 6.9 6.9 2.9 2.2 1 1 1 2 2 2 0 KIP1-like protein U1snRNP70_N PF12220.8 KRZ98505.1 - 0.91 10.2 5.4 1.5 9.5 5.4 1.5 1 1 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF2570 PF10828.8 KRZ98505.1 - 6.8 6.6 10.6 12 5.8 1.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) Prefoldin PF02996.17 KRZ98506.1 - 1.1e-08 35.1 0.3 1.1e-08 35.1 0.3 4.1 3 1 0 3 3 3 1 Prefoldin subunit FtsX_ECD PF18075.1 KRZ98506.1 - 4.5 8.0 14.3 19 6.0 0.4 4.7 3 1 1 4 4 4 0 FtsX extracellular domain U3snoRNP10 PF12397.8 KRZ98507.1 - 6e-11 42.7 1.7 1.2e-10 41.7 0.1 2.2 3 0 0 3 3 3 1 U3 small nucleolar RNA-associated protein 10 Phage_Treg PF04761.12 KRZ98507.1 - 0.046 13.8 0.1 0.13 12.4 0.1 1.7 1 0 0 1 1 1 0 Lactococcus bacteriophage putative transcription regulator AA_permease PF00324.21 KRZ98508.1 - 7.2e-110 367.8 40.7 8.7e-110 367.5 40.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KRZ98508.1 - 1.8e-25 89.7 42.5 2.2e-25 89.4 42.5 1.1 1 0 0 1 1 1 1 Amino acid permease Pet100 PF09803.9 KRZ98508.1 - 0.0048 17.4 0.0 0.012 16.1 0.0 1.6 1 0 0 1 1 1 1 Pet100 Secretin PF00263.21 KRZ98509.1 - 0.045 13.4 0.0 0.048 13.3 0.0 1.1 1 0 0 1 1 1 0 Bacterial type II and III secretion system protein MBF1 PF08523.10 KRZ98510.1 - 2e-24 85.8 0.6 2e-24 85.8 0.6 1.9 2 1 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 KRZ98510.1 - 2.1e-14 53.3 0.5 5.8e-14 51.9 0.4 1.7 2 0 0 2 2 2 1 Helix-turn-helix HTH_19 PF12844.7 KRZ98510.1 - 2.1e-06 27.6 0.5 3.5e-06 26.9 0.5 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.6 KRZ98510.1 - 2.2e-06 27.9 0.0 4e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain MqsA_antitoxin PF15731.5 KRZ98510.1 - 0.12 12.5 0.0 0.16 12.1 0.0 1.2 1 0 0 1 1 1 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA HTH_25 PF13413.6 KRZ98510.1 - 0.13 12.2 0.1 0.21 11.4 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain TRAP-gamma PF07074.12 KRZ98510.1 - 0.2 11.2 0.4 0.28 10.7 0.4 1.2 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) Steroid_dh PF02544.16 KRZ98511.1 - 4.6e-32 111.1 11.0 1.3e-31 109.7 11.0 1.7 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 KRZ98511.1 - 0.0096 15.5 2.9 0.021 14.3 2.9 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) SelR PF01641.18 KRZ98512.1 - 6.8e-49 165.0 0.2 7.7e-49 164.8 0.2 1.0 1 0 0 1 1 1 1 SelR domain Yippee-Mis18 PF03226.14 KRZ98512.1 - 0.034 14.4 0.6 0.076 13.2 0.6 1.6 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly IMD PF08397.11 KRZ98514.1 - 8.4e-06 25.3 3.1 8.4e-06 25.3 3.1 1.9 2 0 0 2 2 2 1 IRSp53/MIM homology domain Cache_3-Cache_2 PF17201.4 KRZ98514.1 - 0.29 10.4 8.0 0.57 9.4 0.7 2.3 2 0 0 2 2 2 0 Cache 3/Cache 2 fusion domain OmpH PF03938.14 KRZ98514.1 - 2.5 8.4 9.4 0.45 10.9 1.2 2.6 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) BATS PF06968.13 KRZ98515.1 - 2.7e-24 85.1 0.3 9e-24 83.4 0.0 2.1 2 1 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 KRZ98515.1 - 1e-17 65.0 0.2 4.6e-17 62.9 0.1 2.0 2 0 0 2 2 2 1 Radical SAM superfamily INPP5B_PH PF16776.5 KRZ98515.1 - 0.0083 15.9 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 Type II inositol 1,4,5-trisphosphate 5-phosphatase PH domain His_biosynth PF00977.21 KRZ98515.1 - 0.094 12.2 0.2 0.2 11.1 0.1 1.6 2 0 0 2 2 2 0 Histidine biosynthesis protein DUF2855 PF11017.8 KRZ98515.1 - 0.11 12.2 0.1 0.17 11.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2855) Ribosomal_L22e PF01776.17 KRZ98516.1 - 3.6e-38 130.3 1.6 4.4e-38 130.0 1.6 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family Aminotran_1_2 PF00155.21 KRZ98517.1 - 1.6e-73 248.0 0.0 2e-73 247.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KRZ98517.1 - 1.5e-06 27.0 0.0 2.5e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KRZ98517.1 - 0.0001 21.4 0.0 0.00017 20.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Preseq_ALAS PF09029.10 KRZ98517.1 - 0.001 19.6 0.9 0.0024 18.4 0.9 1.6 1 0 0 1 1 1 1 5-aminolevulinate synthase presequence DegT_DnrJ_EryC1 PF01041.17 KRZ98517.1 - 0.0084 15.4 0.8 0.061 12.6 0.8 2.1 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 KRZ98518.1 - 6.7e-28 97.3 0.0 7.8e-28 97.1 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KRZ98518.1 - 0.00029 19.9 0.0 0.00036 19.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KRZ98518.1 - 0.00086 18.6 0.0 0.0023 17.2 0.0 1.5 1 1 1 2 2 2 1 Aminotransferase class I and II GDC-P PF02347.16 KRZ98518.1 - 0.25 10.1 0.0 0.29 9.9 0.0 1.1 1 0 0 1 1 1 0 Glycine cleavage system P-protein CRCB PF02537.15 KRZ98519.1 - 3.8e-30 104.1 19.8 2.7e-19 69.2 7.1 2.4 2 0 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) TMEM208_SND2 PF05620.11 KRZ98519.1 - 0.14 11.9 0.2 0.14 11.9 0.2 2.1 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 FMO-like PF00743.19 KRZ98520.1 - 4.5e-22 78.2 2.0 6.3e-21 74.4 2.0 2.3 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KRZ98520.1 - 6.1e-21 75.0 0.3 6.1e-18 65.1 0.2 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KRZ98520.1 - 1.5e-13 50.7 0.0 2.4e-12 46.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KRZ98520.1 - 6.4e-12 45.3 0.1 2.1e-09 37.0 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KRZ98520.1 - 1.4e-05 25.2 0.0 3.9e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KRZ98520.1 - 2.9e-05 23.5 0.1 7.4e-05 22.2 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 KRZ98520.1 - 6.7e-05 23.4 0.1 0.1 13.2 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KRZ98520.1 - 0.00083 18.5 0.5 0.0059 15.7 0.3 2.1 2 0 0 2 2 2 1 FAD binding domain 2-Hacid_dh_C PF02826.19 KRZ98520.1 - 0.0013 18.2 0.1 0.13 11.6 0.0 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 KRZ98520.1 - 0.0073 16.7 0.0 12 6.4 0.0 3.4 3 1 0 3 3 3 0 Putative NAD(P)-binding TrkA_N PF02254.18 KRZ98520.1 - 0.012 15.8 0.1 0.12 12.6 0.0 2.5 3 0 0 3 3 2 0 TrkA-N domain HI0933_like PF03486.14 KRZ98520.1 - 0.018 13.8 0.2 0.037 12.7 0.1 1.6 2 0 0 2 2 2 0 HI0933-like protein DAO PF01266.24 KRZ98520.1 - 0.05 13.2 0.4 1.6 8.3 0.1 2.5 3 0 0 3 3 3 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KRZ98520.1 - 0.061 12.4 0.0 0.15 11.1 0.0 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein IlvN PF07991.12 KRZ98520.1 - 0.083 12.5 0.0 14 5.2 0.0 2.8 3 0 0 3 3 3 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain FAD_oxidored PF12831.7 KRZ98520.1 - 0.11 11.9 0.1 0.74 9.1 0.1 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase adh_short PF00106.25 KRZ98520.1 - 0.11 12.0 0.1 7.2 6.0 0.0 2.2 2 0 0 2 2 2 0 short chain dehydrogenase GIDA PF01134.22 KRZ98520.1 - 0.17 10.9 2.4 0.46 9.5 0.2 2.6 3 0 0 3 3 3 0 Glucose inhibited division protein A Mpp10 PF04006.12 KRZ98521.1 - 4.3e-136 454.9 77.7 5.2e-136 454.6 77.7 1.0 1 0 0 1 1 1 1 Mpp10 protein THAP PF05485.12 KRZ98521.1 - 1.1 10.3 7.4 17 6.4 0.2 3.0 2 0 0 2 2 2 0 THAP domain FtsJ PF01728.19 KRZ98522.1 - 2.5e-52 177.6 0.0 2.9e-52 177.3 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 KRZ98522.1 - 0.00043 20.1 0.1 0.014 15.2 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KRZ98522.1 - 0.022 14.6 0.0 0.033 14.0 0.0 1.3 1 1 0 1 1 1 0 Methyltransferase domain DUF364 PF04016.12 KRZ98522.1 - 0.084 12.5 0.0 4.1 7.0 0.0 2.3 2 0 0 2 2 2 0 Putative heavy-metal chelation F-box-like PF12937.7 KRZ98523.1 - 0.17 11.8 0.8 0.41 10.6 0.8 1.7 1 0 0 1 1 1 0 F-box-like LRR_8 PF13855.6 KRZ98523.1 - 1.4 8.7 13.9 0.04 13.7 2.1 3.5 2 2 1 3 3 3 0 Leucine rich repeat LRR_4 PF12799.7 KRZ98523.1 - 4.5 7.8 21.2 1.3 9.6 1.3 5.4 4 2 3 7 7 7 0 Leucine Rich repeats (2 copies) 2OG-FeII_Oxy_2 PF13532.6 KRZ98524.1 - 1.8e-23 83.7 0.0 3e-23 83.1 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-GRF PF06839.12 KRZ98524.1 - 0.051 13.7 6.9 0.096 12.8 6.9 1.5 1 0 0 1 1 1 0 GRF zinc finger 2OG-FeII_Oxy PF03171.20 KRZ98524.1 - 0.13 12.8 0.0 0.32 11.5 0.0 1.7 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily FAM104 PF15434.6 KRZ98525.1 - 0.17 12.5 2.7 0.16 12.6 1.1 1.6 1 1 1 2 2 2 0 Family 104 Glyco_hydro_17 PF00332.18 KRZ98526.1 - 0.00021 21.0 2.0 0.00021 21.0 2.0 2.5 2 1 1 3 3 3 1 Glycosyl hydrolases family 17 Alg6_Alg8 PF03155.15 KRZ98527.1 - 2.5e-134 448.9 29.1 3.1e-134 448.6 29.1 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Asparaginase_2 PF01112.18 KRZ98528.1 - 2.8e-17 62.7 0.1 5.9e-17 61.6 0.1 1.5 1 1 0 1 1 1 1 Asparaginase RhoGAP-FF1 PF16512.5 KRZ98528.1 - 0.034 14.8 0.2 0.17 12.6 0.0 2.2 3 0 0 3 3 3 0 p190-A and -B Rho GAPs FF domain Com_YlbF PF06133.11 KRZ98528.1 - 0.28 11.8 3.2 0.27 11.9 0.4 2.2 2 0 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA Ribosomal_L24e PF01246.20 KRZ98529.1 - 2.1e-29 101.5 0.1 2.1e-29 101.5 0.1 2.0 2 0 0 2 2 2 1 Ribosomal protein L24e DASH_Spc34 PF08657.10 KRZ98530.1 - 5.3e-63 213.2 19.4 2.6e-62 210.9 19.4 1.8 1 1 0 1 1 1 1 DASH complex subunit Spc34 Opi1 PF08618.10 KRZ98530.1 - 0.033 13.4 0.3 0.066 12.4 0.3 1.4 1 0 0 1 1 1 0 Transcription factor Opi1 Syntaxin-6_N PF09177.11 KRZ98530.1 - 0.17 12.5 5.9 0.061 13.9 1.9 2.4 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Scaffolding_pro PF11418.8 KRZ98530.1 - 0.22 12.1 4.3 0.099 13.2 0.9 2.3 2 2 0 2 2 2 0 Phi29 scaffolding protein HNF-1_N PF04814.13 KRZ98530.1 - 5.2 7.6 8.1 0.39 11.3 1.0 2.0 2 0 0 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus Peptidase_M22 PF00814.25 KRZ98531.1 - 1.3e-84 284.1 0.0 1.6e-84 283.8 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 KRZ98531.1 - 0.04 13.6 0.0 0.4 10.3 0.1 2.0 2 0 0 2 2 2 0 Carbamoyltransferase N-terminus DnaJ PF00226.31 KRZ98532.1 - 3.2e-20 72.0 3.9 8.7e-20 70.6 3.9 1.8 1 0 0 1 1 1 1 DnaJ domain RRM_1 PF00076.22 KRZ98532.1 - 2e-07 30.7 0.0 5.7e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4523 PF15023.6 KRZ98532.1 - 0.014 15.3 0.3 0.052 13.4 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4523) INCENP_ARK-bind PF03941.15 KRZ98532.1 - 0.041 13.8 0.0 0.13 12.3 0.0 1.8 1 0 0 1 1 1 0 Inner centromere protein, ARK binding region DUF543 PF04418.12 KRZ98533.1 - 1.3e-31 108.4 0.2 1.5e-31 108.2 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Sugar_tr PF00083.24 KRZ98534.1 - 3.3e-40 138.3 3.2 4.5e-40 137.9 3.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KRZ98534.1 - 6e-18 64.9 7.9 6e-18 64.9 7.9 1.5 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KRZ98534.1 - 0.00015 20.4 0.3 0.00018 20.1 0.3 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 KRZ98534.1 - 0.0019 17.6 2.1 0.0027 17.1 2.1 1.1 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Sugar_tr PF00083.24 KRZ98535.1 - 5.3e-12 45.3 3.9 5.7e-12 45.2 3.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KRZ98535.1 - 2.5e-05 23.4 2.6 3e-05 23.1 2.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF5379 PF17350.2 KRZ98535.1 - 0.053 13.8 5.7 0.062 13.6 0.9 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5379) PAP2_3 PF14378.6 KRZ98536.1 - 1.1e-17 64.3 13.9 1.5e-17 63.9 13.9 1.2 1 0 0 1 1 1 1 PAP2 superfamily PAP2 PF01569.21 KRZ98536.1 - 8.3e-11 41.8 8.0 1.8e-10 40.7 8.0 1.5 1 0 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.6 KRZ98536.1 - 4.4 7.9 13.3 0.45 11.1 8.5 1.8 2 0 0 2 2 2 0 PAP2 superfamily C-terminal CFEM PF05730.11 KRZ98537.1 - 3.8e-25 87.8 30.6 7.7e-14 51.5 5.5 3.9 4 0 0 4 4 4 2 CFEM domain Flocculin_t3 PF13928.6 KRZ98537.1 - 2.2e-10 40.8 15.0 2.2e-10 40.8 15.0 8.5 7 3 0 7 7 7 1 Flocculin type 3 repeat Gamma-thionin PF00304.20 KRZ98537.1 - 2.2 8.6 6.5 9.6 6.6 0.9 2.8 2 0 0 2 2 2 0 Gamma-thionin family adh_short_C2 PF13561.6 KRZ98538.1 - 3.9e-58 196.8 0.8 5.4e-58 196.3 0.8 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KRZ98538.1 - 2e-54 184.1 1.5 2.3e-54 183.8 1.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KRZ98538.1 - 1e-14 54.8 0.3 1.4e-14 54.4 0.3 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KRZ98538.1 - 0.00093 18.7 0.1 0.003 17.1 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KRZ98538.1 - 0.066 12.6 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KRZ98538.1 - 0.099 11.7 0.1 0.22 10.6 0.1 1.6 1 1 0 1 1 1 0 RmlD substrate binding domain ADH_zinc_N PF00107.26 KRZ98539.1 - 0.00076 19.5 0.0 0.002 18.1 0.0 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase DXP_reductoisom PF02670.16 KRZ98539.1 - 0.023 15.4 0.1 0.046 14.4 0.1 1.5 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Semialdhyde_dh PF01118.24 KRZ98539.1 - 0.043 14.3 0.0 0.079 13.4 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.6 KRZ98539.1 - 0.088 13.9 0.0 0.27 12.3 0.0 1.8 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Ferritin_2 PF13668.6 KRZ98540.1 - 2.1e-40 138.1 4.0 3.2e-40 137.5 4.0 1.3 1 0 0 1 1 1 1 Ferritin-like domain DUF4439 PF14530.6 KRZ98540.1 - 0.018 15.7 0.1 0.031 14.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4439) PMT PF02366.18 KRZ98542.1 - 1e-82 277.4 18.7 1e-82 277.4 18.7 2.1 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KRZ98542.1 - 2.2e-56 190.6 18.2 2.2e-56 190.6 18.2 2.5 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KRZ98542.1 - 8.4e-21 74.7 0.1 2e-20 73.4 0.1 1.5 1 0 0 1 1 1 1 MIR domain DUF3533 PF12051.8 KRZ98543.1 - 3.8e-140 467.1 21.8 4.5e-140 466.9 21.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) PDR_CDR PF06422.12 KRZ98543.1 - 0.00019 21.3 0.2 0.00019 21.3 0.2 3.8 4 1 1 5 5 5 1 CDR ABC transporter MRAP PF15183.6 KRZ98543.1 - 2.4 8.2 7.1 19 5.3 3.3 2.8 2 0 0 2 2 2 0 Melanocortin-2 receptor accessory protein family DUF4472 PF14739.6 KRZ98544.1 - 0.0079 16.9 8.3 0.0079 16.9 8.3 4.0 3 1 1 4 4 4 1 Domain of unknown function (DUF4472) IKKbetaNEMObind PF12179.8 KRZ98544.1 - 0.043 13.8 0.5 0.13 12.3 0.5 1.9 1 0 0 1 1 1 0 I-kappa-kinase-beta NEMO binding domain bZIP_1 PF00170.21 KRZ98544.1 - 0.25 11.4 27.4 1.5 9.0 0.9 5.5 3 1 2 5 5 5 0 bZIP transcription factor Cep57_MT_bd PF06657.13 KRZ98544.1 - 1.1 9.7 8.7 0.21 12.1 0.7 3.5 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 GIT_CC PF16559.5 KRZ98544.1 - 4.7 7.1 18.0 3.5 7.6 11.3 2.9 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor zf-CCHC PF00098.23 KRZ98545.1 - 0.027 14.6 1.1 0.039 14.0 1.1 1.3 1 0 0 1 1 1 0 Zinc knuckle Hexokinase_1 PF00349.21 KRZ98546.1 - 4.7e-73 245.3 0.0 1.3e-72 243.9 0.0 1.7 2 0 0 2 2 2 1 Hexokinase Hexokinase_2 PF03727.16 KRZ98546.1 - 1.1e-72 244.3 0.0 1.5e-72 243.9 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Glutaredoxin PF00462.24 KRZ98547.1 - 1.5e-08 34.7 0.0 2e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_9 PF14595.6 KRZ98547.1 - 0.0035 17.1 0.0 0.0046 16.7 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KRZ98547.1 - 0.01 16.3 0.4 0.017 15.6 0.4 1.5 1 1 0 1 1 1 0 Thioredoxin-like domain Ribosomal_L18A PF01775.17 KRZ98547.1 - 0.053 13.6 0.0 0.08 13.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A Thioredoxin_3 PF13192.6 KRZ98547.1 - 0.15 12.1 0.0 0.45 10.6 0.0 1.8 1 1 0 1 1 1 0 Thioredoxin domain SHMT PF00464.19 KRZ98548.1 - 3.7e-209 694.2 0.0 4.4e-209 694.0 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 KRZ98548.1 - 1.5e-08 34.2 0.0 3.5e-08 33.0 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KRZ98548.1 - 9.7e-05 21.5 0.0 0.00015 20.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KRZ98548.1 - 0.0013 18.1 0.0 0.0028 17.0 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 KRZ98548.1 - 0.044 12.3 0.0 0.084 11.4 0.0 1.4 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Cut12 PF11500.8 KRZ98548.1 - 0.092 12.7 0.3 0.18 11.8 0.3 1.4 1 0 0 1 1 1 0 Spindle pole body formation-associated protein DUF4559 PF15112.6 KRZ98548.1 - 0.11 12.2 2.0 0.31 10.7 2.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4559) ORMDL PF04061.14 KRZ98549.1 - 1e-56 190.5 6.2 1.3e-56 190.1 6.2 1.1 1 0 0 1 1 1 1 ORMDL family RCC1 PF00415.18 KRZ98550.1 - 3.2e-16 59.7 1.3 0.00064 20.3 0.0 5.3 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KRZ98550.1 - 9.9e-15 53.9 8.3 3.4e-09 36.3 0.2 5.1 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat Pallilysin PF18663.1 KRZ98550.1 - 0.14 12.2 0.1 6.7 6.7 0.0 2.5 2 0 0 2 2 2 0 Pallilysin beta barrel domain TAFII28 PF04719.14 KRZ98552.1 - 4e-28 97.3 0.0 1.4e-27 95.6 0.0 1.8 1 1 0 1 1 1 1 hTAFII28-like protein conserved region Methyltransf_11 PF08241.12 KRZ98554.1 - 1.5e-12 48.0 0.0 2.3e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KRZ98554.1 - 4.7e-10 40.1 0.0 7.6e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KRZ98554.1 - 8.6e-07 28.9 0.0 1.2e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KRZ98554.1 - 2.9e-06 27.2 0.0 4e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KRZ98554.1 - 5.6e-06 27.0 0.3 1.8e-05 25.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.11 KRZ98554.1 - 0.0025 16.8 0.0 0.0039 16.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) HA1 PF18239.1 KRZ98554.1 - 0.084 12.7 0.0 0.2 11.6 0.0 1.7 1 0 0 1 1 1 0 Hemagglutinin I MetW PF07021.12 KRZ98554.1 - 0.13 11.8 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW LCM PF04072.14 KRZ98555.1 - 1.1e-24 87.4 0.0 1.5e-24 87.0 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase NPL PF17800.1 KRZ98555.1 - 0.1 13.1 0.0 0.22 12.1 0.0 1.5 1 0 0 1 1 1 0 Nucleoplasmin-like domain Methyltransf_28 PF02636.17 KRZ98556.1 - 3.1e-88 295.8 0.0 4e-88 295.4 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PRMT5 PF05185.16 KRZ98556.1 - 0.21 11.4 1.4 2.3 8.0 0.0 2.7 4 0 0 4 4 4 0 PRMT5 arginine-N-methyltransferase DEAD PF00270.29 KRZ98557.1 - 1.5e-35 122.5 0.3 2.6e-35 121.8 0.3 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KRZ98557.1 - 7.5e-27 93.9 0.0 2.4e-26 92.3 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KRZ98557.1 - 4.2e-07 30.1 1.0 1e-06 28.9 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KRZ98557.1 - 0.0065 16.2 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KRZ98557.1 - 0.0099 16.2 1.0 0.049 13.9 0.0 2.5 2 1 1 3 3 3 1 AAA domain Sod_Fe_C PF02777.18 KRZ98558.1 - 4.7e-14 52.4 0.2 2.5e-07 30.8 0.0 2.4 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Vpu PF00558.19 KRZ98558.1 - 0.93 9.3 3.3 2.5 7.9 3.3 1.7 1 0 0 1 1 1 0 Vpu protein Pal1 PF08316.11 KRZ98559.1 - 3.4e-53 180.1 3.7 3.4e-53 180.1 3.7 2.5 3 0 0 3 3 3 1 Pal1 cell morphology protein FYVE PF01363.21 KRZ98560.1 - 3.6e-14 52.7 8.4 8.6e-14 51.4 8.4 1.7 1 0 0 1 1 1 1 FYVE zinc finger zf-RING_UBOX PF13445.6 KRZ98560.1 - 0.55 10.3 8.1 0.84 9.7 4.1 2.6 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING_5 PF14634.6 KRZ98560.1 - 1 9.4 13.9 0.035 14.1 6.6 2.1 2 0 0 2 2 2 0 zinc-RING finger domain MFS_1 PF07690.16 KRZ98561.1 - 6.7e-18 64.7 27.3 6.7e-18 64.7 27.3 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily AMIN PF11741.8 KRZ98563.1 - 0.075 13.2 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 AMIN domain LSM PF01423.22 KRZ98564.1 - 6.9e-19 67.3 0.3 9.1e-19 66.9 0.3 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KRZ98564.1 - 0.0007 19.7 0.1 0.00094 19.3 0.1 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 KRZ98564.1 - 0.022 14.8 0.1 0.028 14.5 0.1 1.2 1 0 0 1 1 1 0 Scd6-like Sm domain Hfq PF17209.3 KRZ98564.1 - 0.048 13.3 0.1 0.072 12.7 0.1 1.3 1 0 0 1 1 1 0 Hfq protein F1F0-ATPsyn_F PF10791.9 KRZ98565.1 - 9.8e-39 131.7 0.1 1.1e-38 131.6 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi Pkinase PF00069.25 KRZ98566.1 - 3e-67 226.8 0.0 9.3e-62 208.8 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KRZ98566.1 - 4.1e-34 118.0 0.0 1e-32 113.4 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 KRZ98566.1 - 6.2e-18 64.3 0.0 1.4e-17 63.2 0.0 1.7 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.6 KRZ98566.1 - 2.8e-05 23.6 0.0 6.2e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KRZ98566.1 - 0.0005 19.5 0.0 0.00099 18.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KRZ98566.1 - 0.0031 16.5 0.0 0.0031 16.5 0.0 2.4 3 0 0 3 3 3 1 Haspin like kinase domain APH PF01636.23 KRZ98566.1 - 0.021 14.8 0.1 0.14 12.1 0.0 2.0 1 1 0 2 2 2 0 Phosphotransferase enzyme family Acetyltransf_10 PF13673.7 KRZ98568.1 - 0.079 12.9 0.1 0.26 11.2 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Fungal_trans PF04082.18 KRZ98569.1 - 1.2e-18 67.1 8.4 1.2e-18 67.1 8.4 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain FMO-like PF00743.19 KRZ98570.1 - 1.3e-28 99.8 0.8 1.1e-15 57.1 0.2 3.1 2 1 1 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KRZ98570.1 - 6.1e-12 45.4 0.0 1.1e-10 41.2 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KRZ98570.1 - 1.1e-09 38.0 0.9 9.1e-07 28.4 0.1 3.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KRZ98570.1 - 5.3e-05 23.3 0.0 0.011 15.8 0.0 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 KRZ98570.1 - 0.0002 20.6 0.2 0.025 13.7 0.0 3.1 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 KRZ98570.1 - 0.0023 17.2 0.0 1 8.6 0.0 2.4 2 0 0 2 2 2 2 Thi4 family NAD_binding_8 PF13450.6 KRZ98570.1 - 0.0026 17.9 0.0 0.035 14.4 0.0 2.5 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KRZ98570.1 - 0.0067 16.0 0.0 2.8 7.4 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase TauD PF02668.16 KRZ98571.1 - 1.6e-27 97.0 0.0 2.3e-27 96.5 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family NADH_oxidored PF08040.11 KRZ98572.1 - 0.037 13.7 0.0 0.095 12.4 0.0 1.7 1 0 0 1 1 1 0 MNLL subunit TRAPPC10 PF12584.8 KRZ98573.1 - 1.9e-16 60.2 0.1 2.4e-15 56.5 0.0 2.3 2 0 0 2 2 2 1 Trafficking protein particle complex subunit 10, TRAPPC10 Gryzun-like PF12742.7 KRZ98573.1 - 0.067 13.2 0.1 0.41 10.7 0.0 2.5 2 0 0 2 2 2 0 Gryzun, putative Golgi trafficking TPR_12 PF13424.6 KRZ98573.1 - 0.14 12.5 0.0 0.63 10.4 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Complex1_LYR PF05347.15 KRZ98575.1 - 2.5e-17 62.7 0.5 3.1e-17 62.4 0.5 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KRZ98575.1 - 4.4e-06 27.4 0.3 5.1e-06 27.2 0.3 1.0 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 KRZ98575.1 - 0.0089 16.6 0.0 0.0091 16.6 0.0 1.1 1 0 0 1 1 1 1 Complex1_LYR-like DnaJ-X PF14308.6 KRZ98576.1 - 6.4e-65 218.5 8.4 6.4e-65 218.5 8.4 2.2 2 0 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.31 KRZ98576.1 - 4.6e-25 87.5 2.3 8e-25 86.8 0.4 2.5 2 0 0 2 2 2 1 DnaJ domain SSI PF00720.17 KRZ98576.1 - 0.063 13.2 0.0 0.19 11.7 0.0 1.8 1 0 0 1 1 1 0 Subtilisin inhibitor-like Mucin PF01456.17 KRZ98576.1 - 0.86 9.6 5.6 1.8 8.6 5.6 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein MFS_1 PF07690.16 KRZ98577.1 - 5.5e-30 104.5 8.6 6.9e-30 104.1 8.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KRZ98577.1 - 5.2e-11 41.7 4.8 6.1e-11 41.5 4.8 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KRZ98577.1 - 2.3e-09 36.6 2.6 3.1e-09 36.2 2.6 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter HlyIII PF03006.20 KRZ98577.1 - 0.0013 18.5 0.3 0.0031 17.2 0.3 1.6 1 0 0 1 1 1 1 Haemolysin-III related DEAD PF00270.29 KRZ98578.1 - 6.6e-13 48.8 0.0 1.9e-12 47.3 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KRZ98578.1 - 2.3e-10 40.8 0.1 1e-09 38.7 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KRZ98578.1 - 0.016 15.3 0.0 0.048 13.7 0.0 1.9 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit zf-Di19 PF05605.12 KRZ98578.1 - 3.1 8.2 7.2 2.2 8.6 0.8 2.8 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Bul1_C PF04426.12 KRZ98581.1 - 1.9e-19 70.1 7.3 1.9e-19 70.1 7.3 2.2 2 1 0 2 2 2 1 Bul1 C terminus RasGAP_C PF03836.15 KRZ98581.1 - 0.099 12.8 0.1 0.18 11.9 0.1 1.4 1 0 0 1 1 1 0 RasGAP C-terminus Bul1_N PF04425.12 KRZ98582.1 - 2.5e-103 346.3 8.8 5.5e-103 345.1 8.8 1.5 1 1 0 1 1 1 1 Bul1 N terminus Bul1_N PF04425.12 KRZ98583.1 - 5.4e-39 134.2 7.6 3.7e-33 115.0 0.5 3.3 1 1 2 3 3 3 3 Bul1 N terminus Bul1_C PF04426.12 KRZ98583.1 - 1e-14 54.6 2.2 8.2e-09 35.3 0.0 2.6 1 1 1 2 2 2 2 Bul1 C terminus Transp_cyt_pur PF02133.15 KRZ98584.1 - 5.4e-11 41.9 38.4 6.3e-11 41.7 31.4 2.3 2 1 0 2 2 2 2 Permease for cytosine/purines, uracil, thiamine, allantoin DUF4820 PF16091.5 KRZ98584.1 - 0.24 10.8 0.0 0.48 9.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) MatE PF01554.18 KRZ98585.1 - 1.1e-24 86.9 12.8 1.1e-24 86.9 12.8 1.5 2 0 0 2 2 2 1 MatE Sugar_tr PF00083.24 KRZ98586.1 - 2.3e-76 257.5 27.6 2.6e-76 257.3 27.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KRZ98586.1 - 9.3e-25 87.3 49.3 6.9e-24 84.4 22.5 2.6 1 1 2 3 3 3 3 Major Facilitator Superfamily OATP PF03137.20 KRZ98586.1 - 0.0049 15.2 1.6 0.0049 15.2 1.6 2.8 2 1 1 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family Glyco_hydro_2_N PF02837.18 KRZ98588.1 - 7.4e-08 32.5 0.1 1.1e-07 31.9 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain PX PF00787.24 KRZ98590.1 - 2.6e-13 50.0 0.2 9.5e-13 48.1 0.2 2.0 1 0 0 1 1 1 1 PX domain Sin3_corepress PF08295.12 KRZ98590.1 - 0.98 9.5 6.4 0.19 11.8 0.3 2.8 4 0 0 4 4 4 0 Sin3 family co-repressor rRNA_proc-arch PF13234.6 KRZ98590.1 - 1.1 9.2 8.7 0.19 11.6 0.3 3.0 3 1 0 3 3 3 0 rRNA-processing arch domain PALP PF00291.25 KRZ98591.1 - 6.1e-57 193.3 0.0 7.2e-57 193.0 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Helicase_C_2 PF13307.6 KRZ98592.1 - 1.7e-56 191.1 0.5 5.3e-56 189.5 0.1 2.1 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.15 KRZ98592.1 - 4.3e-48 163.3 1.6 1.2e-47 161.8 1.6 1.8 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.15 KRZ98592.1 - 0.00023 21.2 0.4 0.37 10.8 0.0 3.1 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit HBB PF06777.11 KRZ98592.1 - 0.00037 20.2 0.0 0.0012 18.6 0.0 1.9 1 0 0 1 1 1 1 Helical and beta-bridge domain PhoH PF02562.16 KRZ98592.1 - 0.0076 15.7 0.2 1.3 8.4 0.0 2.8 3 0 0 3 3 3 1 PhoH-like protein DEAD PF00270.29 KRZ98592.1 - 0.074 12.8 1.1 2.9 7.6 0.3 2.9 2 1 0 2 2 2 0 DEAD/DEAH box helicase AAA_22 PF13401.6 KRZ98592.1 - 0.092 13.0 0.1 5 7.4 0.1 2.7 2 0 0 2 2 2 0 AAA domain DUF5376 PF17346.2 KRZ98592.1 - 0.28 11.5 5.1 0.26 11.6 2.0 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5376) Glyoxalase_2 PF12681.7 KRZ98592.1 - 6.3 6.8 7.3 0.97 9.4 0.4 3.0 3 0 0 3 3 3 0 Glyoxalase-like domain 2OG-FeII_Oxy_3 PF13640.6 KRZ98593.1 - 1.7e-10 41.7 0.1 3.1e-10 40.8 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Nic96 PF04097.14 KRZ98594.1 - 9e-182 605.8 4.4 1e-181 605.6 4.4 1.0 1 0 0 1 1 1 1 Nup93/Nic96 DUF3741 PF12552.8 KRZ98594.1 - 0.013 15.4 0.3 0.039 13.9 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3741) DUF5131 PF07505.11 KRZ98594.1 - 0.036 13.5 0.0 0.057 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF5131) Ran_BP1 PF00638.18 KRZ98595.1 - 6.4e-23 81.3 0.0 1.4e-22 80.2 0.0 1.6 2 0 0 2 2 2 1 RanBP1 domain RabGAP-TBC PF00566.18 KRZ98596.1 - 1.6e-17 63.9 10.8 1.1e-16 61.2 10.8 2.4 1 1 0 1 1 1 1 Rab-GTPase-TBC domain DnaJ_C PF01556.18 KRZ98597.1 - 2.8e-28 98.9 0.7 4.4e-28 98.2 0.7 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KRZ98597.1 - 4.7e-23 81.1 6.9 9.7e-23 80.1 6.9 1.6 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KRZ98597.1 - 2e-12 47.3 21.7 3.2e-12 46.6 21.7 1.3 1 0 0 1 1 1 1 DnaJ central domain Cytochrom_CIII PF02085.16 KRZ98597.1 - 0.0047 17.3 6.9 0.017 15.4 6.9 1.9 1 0 0 1 1 1 1 Class III cytochrome C family Cytochrom_c3_2 PF14537.6 KRZ98597.1 - 2.2 8.8 14.2 5.4 7.5 2.1 2.5 1 1 0 2 2 2 0 Cytochrome c3 DUF2318 PF10080.9 KRZ98597.1 - 3.1 8.0 9.2 0.71 10.0 4.8 2.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2318) zf-CHY PF05495.12 KRZ98597.1 - 5.4 7.6 8.0 5 7.7 6.3 1.7 1 1 0 1 1 1 0 CHY zinc finger AcetylCoA_hydro PF02550.15 KRZ98598.1 - 6.5e-61 205.8 0.0 1e-60 205.1 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.6 KRZ98598.1 - 1.9e-42 144.8 0.0 2.9e-42 144.2 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain Mito_carr PF00153.27 KRZ98600.1 - 9.2e-48 160.1 0.3 1.7e-16 59.9 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Phi-29_GP16_7 PF06720.11 KRZ98600.1 - 0.17 11.7 0.0 21 5.0 0.0 2.6 3 0 0 3 3 3 0 Bacteriophage phi-29 early protein GP16.7 Ribosomal_S21 PF01165.20 KRZ98601.1 - 9.1e-11 41.3 1.0 9.1e-11 41.3 1.0 1.9 2 0 0 2 2 2 1 Ribosomal protein S21 DUF1681 PF07933.14 KRZ98602.1 - 4.2e-05 23.3 0.0 0.00068 19.4 0.0 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF1681) ERCC3_RAD25_C PF16203.5 KRZ98603.1 - 2.5e-125 416.7 1.4 4.7e-125 415.7 1.4 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 KRZ98603.1 - 7.9e-37 126.2 0.3 1.7e-36 125.1 0.1 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KRZ98603.1 - 1.2e-15 57.9 0.0 2.4e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KRZ98603.1 - 6.8e-12 45.7 0.2 1.6e-11 44.5 0.2 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 KRZ98603.1 - 2.1e-09 36.5 0.0 2.6e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 KRZ98603.1 - 4e-05 23.4 0.0 8.1e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase SBP_bac_6 PF13343.6 KRZ98603.1 - 0.078 12.4 0.0 0.19 11.1 0.0 1.6 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein SRP40_C PF05022.12 KRZ98604.1 - 6.8e-24 84.5 3.0 6.8e-24 84.5 3.0 2.0 2 1 0 2 2 2 1 SRP40, C-terminal domain SEEEED PF14797.6 KRZ98604.1 - 0.089 13.0 52.3 0.16 12.1 52.3 1.6 1 0 0 1 1 1 0 Serine-rich region of AP3B1, clathrin-adaptor complex SDA1 PF05285.12 KRZ98604.1 - 0.26 10.7 26.5 0.27 10.6 26.5 1.2 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 KRZ98604.1 - 0.28 9.4 18.3 0.24 9.6 18.3 1.1 1 0 0 1 1 1 0 CDC45-like protein LAP1C PF05609.12 KRZ98604.1 - 1.2 8.2 16.9 1.2 8.2 16.9 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Zip PF02535.22 KRZ98604.1 - 1.8 7.7 7.9 1.6 7.8 7.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 KRZ98604.1 - 5.7 5.6 13.4 5.4 5.7 13.4 1.1 1 0 0 1 1 1 0 Presenilin Apt1 PF10351.9 KRZ98604.1 - 6 5.6 25.3 6.4 5.5 25.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SMYLE_N PF18615.1 KRZ98604.1 - 9.9 5.6 12.5 11 5.5 12.5 1.0 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain FTR1 PF03239.14 KRZ98606.1 - 5.9e-83 278.6 7.6 8.9e-83 278.0 7.6 1.2 1 0 0 1 1 1 1 Iron permease FTR1 family Pkinase PF00069.25 KRZ98607.1 - 5.2e-65 219.4 0.0 8.7e-65 218.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KRZ98607.1 - 8.4e-30 103.9 0.0 1.4e-29 103.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KRZ98607.1 - 0.017 14.4 0.2 0.14 11.4 0.0 2.4 3 1 0 3 3 3 0 Kinase-like Sugar_tr PF00083.24 KRZ98608.1 - 3.5e-110 369.0 36.3 4.1e-110 368.7 36.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KRZ98608.1 - 3.8e-27 95.1 41.9 1.5e-25 89.9 35.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Gly-zipper_Omp PF13488.6 KRZ98608.1 - 0.0003 20.7 0.8 0.0011 18.9 0.8 1.9 1 0 0 1 1 1 1 Glycine zipper Rick_17kDa_Anti PF05433.15 KRZ98608.1 - 0.0032 17.3 0.9 0.0079 16.0 0.9 1.6 1 0 0 1 1 1 1 Glycine zipper 2TM domain VQ PF05678.14 KRZ98608.1 - 0.0052 16.2 0.1 0.053 13.0 0.0 2.3 2 0 0 2 2 2 1 VQ motif Gly-zipper_YMGG PF13441.6 KRZ98608.1 - 0.048 13.4 2.2 0.12 12.1 2.2 1.6 1 0 0 1 1 1 0 YMGG-like Gly-zipper Cytochrom_C1 PF02167.15 KRZ98609.1 - 2.8e-95 318.2 0.0 3.4e-95 317.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 KRZ98609.1 - 0.0018 18.6 0.0 0.0038 17.5 0.0 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 KRZ98609.1 - 0.015 16.4 0.3 0.039 15.1 0.1 1.9 2 1 0 2 2 2 0 Cytochrome c AAA PF00004.29 KRZ98611.1 - 9.1e-98 323.8 0.0 2.3e-47 160.7 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KRZ98611.1 - 3.2e-26 90.9 3.5 4.9e-14 51.9 1.0 2.9 2 0 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 KRZ98611.1 - 8.7e-20 70.7 1.4 4.1e-19 68.6 0.5 2.6 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 KRZ98611.1 - 1.6e-14 54.0 0.0 3.6e-06 26.8 0.0 3.2 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KRZ98611.1 - 4.4e-14 53.0 0.0 1.6e-07 31.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KRZ98611.1 - 3e-12 47.2 0.1 0.00013 22.4 0.0 4.5 3 2 0 3 3 2 2 AAA ATPase domain AAA_33 PF13671.6 KRZ98611.1 - 8e-12 45.5 0.0 2.4e-06 27.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain CDC48_2 PF02933.17 KRZ98611.1 - 3.6e-11 42.7 0.0 8.6e-11 41.5 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_5 PF07728.14 KRZ98611.1 - 7.1e-11 42.3 0.6 2.7e-05 24.2 0.1 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) TIP49 PF06068.13 KRZ98611.1 - 1.7e-09 37.3 0.1 0.00089 18.6 0.0 2.5 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_22 PF13401.6 KRZ98611.1 - 2e-09 37.9 4.1 0.071 13.4 0.0 4.9 3 2 1 4 4 4 2 AAA domain RNA_helicase PF00910.22 KRZ98611.1 - 9.2e-08 32.4 0.0 0.012 16.0 0.0 3.6 4 0 0 4 4 2 2 RNA helicase AAA_14 PF13173.6 KRZ98611.1 - 1.5e-07 31.5 0.0 0.0058 16.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain Vps4_C PF09336.10 KRZ98611.1 - 2.1e-07 30.9 0.8 3.4e-05 23.8 0.1 3.0 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain IstB_IS21 PF01695.17 KRZ98611.1 - 6e-07 29.4 0.1 0.033 13.9 0.0 2.9 3 0 0 3 3 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.21 KRZ98611.1 - 7.3e-07 28.8 0.6 0.038 13.4 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 KRZ98611.1 - 2.2e-06 28.2 0.0 0.095 13.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 KRZ98611.1 - 4.3e-06 26.6 0.0 0.065 12.9 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_7 PF12775.7 KRZ98611.1 - 5.3e-06 26.1 0.2 0.082 12.4 0.0 2.7 2 1 0 2 2 2 2 P-loop containing dynein motor region ATPase PF06745.13 KRZ98611.1 - 7.4e-06 25.5 0.7 0.66 9.3 0.0 3.5 3 0 0 3 3 3 2 KaiC ABC_tran PF00005.27 KRZ98611.1 - 8e-06 26.4 0.2 0.07 13.6 0.0 3.8 3 1 0 3 3 2 1 ABC transporter Bac_DnaA PF00308.18 KRZ98611.1 - 1.2e-05 25.3 0.0 0.021 14.7 0.0 2.8 3 0 0 3 3 2 1 Bacterial dnaA protein AAA_25 PF13481.6 KRZ98611.1 - 3.5e-05 23.5 6.3 0.22 11.1 0.8 4.4 3 2 1 4 4 3 1 AAA domain Sigma54_activat PF00158.26 KRZ98611.1 - 4.7e-05 23.2 0.0 0.36 10.5 0.0 3.3 3 1 0 3 3 2 2 Sigma-54 interaction domain AAA_28 PF13521.6 KRZ98611.1 - 5.3e-05 23.5 0.0 0.57 10.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain Parvo_NS1 PF01057.17 KRZ98611.1 - 5.8e-05 22.3 0.1 0.13 11.3 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_17 PF13207.6 KRZ98611.1 - 8.9e-05 22.9 0.0 0.38 11.2 0.0 3.0 2 0 0 2 2 2 2 AAA domain DUF815 PF05673.13 KRZ98611.1 - 0.0001 21.6 0.0 0.12 11.6 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF815) ResIII PF04851.15 KRZ98611.1 - 0.00013 22.0 0.0 0.042 13.9 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit TsaE PF02367.17 KRZ98611.1 - 0.00015 21.7 0.0 0.59 10.1 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 KRZ98611.1 - 0.00024 21.0 0.0 1 9.2 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 KRZ98611.1 - 0.00031 20.6 1.9 0.79 9.5 0.0 3.1 3 0 0 3 3 3 2 AAA domain DUF2075 PF09848.9 KRZ98611.1 - 0.00037 19.8 0.0 0.72 9.0 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 KRZ98611.1 - 0.00042 19.8 2.8 0.19 11.1 0.1 2.8 3 0 0 3 3 3 2 PhoH-like protein ATPase_2 PF01637.18 KRZ98611.1 - 0.00075 19.5 1.6 1.2 9.1 0.1 4.1 3 1 0 3 3 3 1 ATPase domain predominantly from Archaea NACHT PF05729.12 KRZ98611.1 - 0.0015 18.4 0.2 2.2 8.2 0.0 3.2 3 0 0 3 3 3 1 NACHT domain AAA_30 PF13604.6 KRZ98611.1 - 0.0017 18.1 0.4 2 8.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 KRZ98611.1 - 0.002 17.4 0.0 1.3 8.3 0.0 3.3 3 0 0 3 3 3 1 Zeta toxin AAA_19 PF13245.6 KRZ98611.1 - 0.0024 18.2 1.4 3.4 8.0 0.0 3.6 3 1 0 4 4 3 1 AAA domain NB-ARC PF00931.22 KRZ98611.1 - 0.0045 16.2 0.5 2.8 7.1 0.0 2.7 3 0 0 3 3 3 1 NB-ARC domain IPT PF01745.16 KRZ98611.1 - 0.013 14.9 0.2 1.7 7.9 0.0 2.4 2 0 0 2 2 2 0 Isopentenyl transferase T2SSE PF00437.20 KRZ98611.1 - 0.019 14.1 0.0 3.4 6.6 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein Cytidylate_kin PF02224.18 KRZ98611.1 - 0.02 14.6 0.0 7.9 6.1 0.0 2.9 2 0 0 2 2 2 0 Cytidylate kinase Zot PF05707.12 KRZ98611.1 - 0.072 12.7 0.0 3.1 7.4 0.0 2.8 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) Sigma54_activ_2 PF14532.6 KRZ98611.1 - 0.078 13.1 0.0 9 6.4 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain KAP_NTPase PF07693.14 KRZ98611.1 - 0.081 12.2 0.3 3.5 6.8 0.0 2.8 2 2 0 3 3 3 0 KAP family P-loop domain NTPase_1 PF03266.15 KRZ98611.1 - 0.086 12.8 3.3 8.2 6.3 0.0 4.1 5 0 0 5 5 4 0 NTPase Viral_helicase1 PF01443.18 KRZ98611.1 - 0.12 12.0 0.0 19 4.9 0.0 2.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.6 KRZ98611.1 - 0.14 11.9 0.0 13 5.6 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_6 PF12774.7 KRZ98611.1 - 0.15 11.0 0.2 7.4 5.4 0.0 2.4 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region eIF-1a PF01176.19 KRZ98611.1 - 0.2 11.5 0.6 1.5 8.7 0.3 2.5 1 1 1 2 2 2 0 Translation initiation factor 1A / IF-1 SRPRB PF09439.10 KRZ98611.1 - 0.4 10.1 2.5 42 3.5 0.1 3.9 4 1 0 4 4 3 0 Signal recognition particle receptor beta subunit HIT PF01230.23 KRZ98612.1 - 4e-23 82.0 0.1 6e-23 81.4 0.1 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KRZ98612.1 - 4.8e-11 43.2 0.3 1.1e-10 42.0 0.0 1.6 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 KRZ98612.1 - 0.0021 17.9 0.7 0.0034 17.2 0.7 1.6 1 1 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Got1 PF04178.12 KRZ98613.1 - 1.2e-33 115.9 19.0 1.6e-33 115.4 19.0 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family HLH PF00010.26 KRZ98614.1 - 4.2e-12 45.8 1.9 4.2e-12 45.8 1.9 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain ALS_ss_C PF10369.9 KRZ98616.1 - 1.2e-16 60.6 0.1 6.4e-16 58.3 0.0 2.2 3 0 0 3 3 3 1 Small subunit of acetolactate synthase ACT PF01842.25 KRZ98616.1 - 1.6e-14 53.4 0.1 3.6e-14 52.2 0.1 1.6 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.6 KRZ98616.1 - 2.5e-06 27.2 0.0 4.3e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 ACT domain SH3_1 PF00018.28 KRZ98618.1 - 8.3e-23 79.7 0.0 3.4e-12 45.8 0.0 2.8 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 KRZ98618.1 - 4.9e-15 55.1 0.0 1.1e-10 41.1 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.24 KRZ98618.1 - 1.8e-13 50.5 0.1 5e-13 49.0 0.1 1.8 1 0 0 1 1 1 1 PX domain SH3_2 PF07653.17 KRZ98618.1 - 9.6e-11 41.2 0.0 4e-10 39.2 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain Thioredoxin_4 PF13462.6 KRZ98620.1 - 1.2e-07 32.1 0.1 5.1e-07 30.0 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin Radial_spoke PF04712.12 KRZ98620.1 - 0.026 13.5 0.2 0.034 13.1 0.2 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein Fungal_trans PF04082.18 KRZ98621.1 - 1.4e-47 162.0 6.3 2.3e-47 161.3 6.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KRZ98621.1 - 0.00011 22.4 2.4 0.00011 22.4 2.4 3.4 3 0 0 3 3 3 1 Zinc finger, C2H2 type FOXP-CC PF16159.5 KRZ98621.1 - 0.0027 18.3 0.5 2.4 8.9 0.0 2.6 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 KRZ98621.1 - 0.014 16.2 1.1 0.014 16.2 1.1 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger FAA_hydrolase PF01557.18 KRZ98622.1 - 3.8e-59 200.0 0.0 4.3e-59 199.8 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family MFS_1 PF07690.16 KRZ98623.1 - 2.2e-41 142.0 13.6 3e-41 141.5 13.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KRZ98623.1 - 7.5e-08 32.1 4.4 2.9e-07 30.1 0.1 2.2 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB Peptidase_M16_C PF05193.21 KRZ98624.1 - 2.7e-20 73.2 0.2 3e-18 66.5 0.0 2.3 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KRZ98624.1 - 8.9e-14 51.7 1.2 2.9e-12 46.8 1.2 2.4 1 1 0 1 1 1 1 Insulinase (Peptidase family M16) CDK2AP PF09806.9 KRZ98624.1 - 0.001 19.2 2.0 0.002 18.3 2.0 1.6 1 0 0 1 1 1 1 Cyclin-dependent kinase 2-associated protein AveC_like PF17198.4 KRZ98625.1 - 0.21 11.0 0.0 0.29 10.5 0.0 1.1 1 0 0 1 1 1 0 Spirocyclase AveC-like His_biosynth PF00977.21 KRZ98626.1 - 4.1e-45 154.0 0.0 2.2e-44 151.6 0.0 2.2 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.28 KRZ98626.1 - 2.2e-13 50.4 0.0 3.6e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 KRZ98626.1 - 1.5e-07 31.2 0.0 2.4e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain ThiG PF05690.14 KRZ98626.1 - 0.0043 16.4 0.0 0.0081 15.5 0.0 1.3 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG Peptidase_S51 PF03575.17 KRZ98626.1 - 0.0069 16.1 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family S51 SARAF PF06682.12 KRZ98628.1 - 0.00033 20.4 0.3 0.0004 20.1 0.3 1.2 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis RCR PF12273.8 KRZ98628.1 - 0.0022 18.6 16.2 0.0052 17.4 16.2 1.7 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red BatD PF13584.6 KRZ98628.1 - 0.0028 16.5 0.0 0.0034 16.3 0.0 1.1 1 0 0 1 1 1 1 Oxygen tolerance BatA PF07584.11 KRZ98628.1 - 0.0037 17.6 2.0 0.0051 17.1 2.0 1.1 1 0 0 1 1 1 1 Aerotolerance regulator N-terminal GRP PF07172.11 KRZ98628.1 - 0.0074 17.0 11.8 0.0074 17.0 11.8 2.3 1 1 1 2 2 2 1 Glycine rich protein family SIT PF15330.6 KRZ98628.1 - 0.0084 16.6 0.2 0.027 14.9 0.2 1.7 1 1 0 1 1 1 1 SHP2-interacting transmembrane adaptor protein, SIT Glucos_trans_II PF14264.6 KRZ98628.1 - 0.044 13.1 0.6 0.056 12.8 0.6 1.1 1 0 0 1 1 1 0 Glucosyl transferase GtrII FAM209 PF15206.6 KRZ98628.1 - 0.045 13.5 0.1 0.055 13.3 0.1 1.2 1 0 0 1 1 1 0 FAM209 family DUF5385 PF17359.2 KRZ98628.1 - 0.16 11.5 0.1 0.23 11.0 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5385) Tweety PF04906.13 KRZ98628.1 - 0.23 10.1 1.1 0.34 9.5 1.1 1.2 1 0 0 1 1 1 0 Tweety AA_permease_2 PF13520.6 KRZ98629.1 - 6.1e-54 183.5 37.4 7.3e-54 183.2 37.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KRZ98629.1 - 1.4e-17 63.5 26.5 1.8e-17 63.1 26.5 1.1 1 0 0 1 1 1 1 Amino acid permease MFS_1 PF07690.16 KRZ98630.1 - 3.2e-27 95.4 26.3 5.1e-25 88.1 21.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF5518 PF17647.1 KRZ98630.1 - 0.12 12.5 12.2 0.07 13.3 2.9 3.0 3 1 0 3 3 3 0 Family of unknown function (DUF5518) Sugar_tr PF00083.24 KRZ98631.1 - 3.9e-73 246.9 18.1 4.4e-73 246.7 18.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KRZ98631.1 - 2.4e-12 46.4 18.9 5.6e-11 42.0 10.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KRZ98631.1 - 0.00017 20.3 5.4 0.00017 20.3 5.4 1.8 2 0 0 2 2 2 1 MFS/sugar transport protein 2OG-FeII_Oxy PF03171.20 KRZ98632.1 - 5e-05 23.7 0.1 0.00026 21.4 0.1 2.1 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily WD40 PF00400.32 KRZ98633.1 - 1.7e-34 117.3 22.1 1.3e-07 32.2 0.2 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat PRP4 PF08799.11 KRZ98633.1 - 1.5e-12 46.8 2.6 2.4e-12 46.2 2.6 1.3 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like ANAPC4_WD40 PF12894.7 KRZ98633.1 - 1.3e-10 41.5 0.2 0.44 10.9 0.0 5.0 2 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KRZ98633.1 - 4.1e-07 29.3 0.1 0.54 9.2 0.0 5.1 2 1 2 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein DHFR_2 PF06442.11 KRZ98633.1 - 0.047 13.5 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 R67 dihydrofolate reductase DUF3929 PF13066.6 KRZ98633.1 - 0.17 12.0 0.0 0.61 10.2 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3929) HDA2-3 PF11496.8 KRZ98634.1 - 5.9e-103 344.0 6.7 5.9e-103 344.0 6.7 2.1 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 LcrG PF07216.12 KRZ98634.1 - 0.017 15.1 1.7 0.059 13.3 1.7 1.9 1 0 0 1 1 1 0 LcrG protein ThiF PF00899.21 KRZ98635.1 - 5.5e-20 71.8 0.0 7.2e-20 71.4 0.0 1.1 1 0 0 1 1 1 1 ThiF family Ccdc124 PF06244.12 KRZ98635.1 - 0.088 13.4 0.1 0.16 12.5 0.1 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 124 /Oxs1 Shikimate_DH PF01488.20 KRZ98635.1 - 0.13 12.3 0.3 0.92 9.6 0.1 2.3 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase Sec23_trunk PF04811.15 KRZ98636.1 - 5.3e-73 245.6 0.0 8.1e-73 245.0 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 KRZ98636.1 - 1.5e-33 115.4 0.7 3.1e-33 114.4 0.7 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 KRZ98636.1 - 5.4e-24 84.0 0.2 1.6e-23 82.5 0.2 1.8 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Gelsolin PF00626.22 KRZ98636.1 - 2.3e-13 49.8 0.0 5.4e-13 48.6 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat zf-Sec23_Sec24 PF04810.15 KRZ98636.1 - 2.6e-11 43.4 9.6 5.1e-11 42.4 9.6 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Vps36-NZF-N PF16988.5 KRZ98636.1 - 0.00038 19.8 0.2 0.0009 18.6 0.2 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-RanBP PF00641.18 KRZ98636.1 - 0.0041 16.4 0.2 0.0087 15.4 0.2 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others DUF4286 PF14114.6 KRZ98637.1 - 0.0079 16.7 0.2 0.016 15.7 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4286) RhoGEF PF00621.20 KRZ98637.1 - 0.0096 16.2 1.4 0.013 15.7 1.4 1.3 1 0 0 1 1 1 1 RhoGEF domain BTHB PF18410.1 KRZ98637.1 - 0.16 11.8 1.0 0.53 10.1 0.3 2.1 2 0 0 2 2 2 0 Basic tilted helix bundle domain Tim17 PF02466.19 KRZ98638.1 - 5.8e-05 23.4 0.2 0.00014 22.2 0.1 1.6 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family La PF05383.17 KRZ98639.1 - 1.5e-16 60.2 0.6 2.8e-16 59.3 0.3 1.6 2 0 0 2 2 2 1 La domain HCO3_cotransp PF00955.21 KRZ98640.1 - 1.9e-77 261.2 16.3 1.2e-39 136.5 6.9 2.1 1 1 1 2 2 2 2 HCO3- transporter family Fungal_trans PF04082.18 KRZ98641.1 - 1.1e-09 37.7 2.8 2e-09 36.9 2.8 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KRZ98641.1 - 3.6e-08 33.4 10.3 6.6e-08 32.5 10.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IL11 PF07400.11 KRZ98641.1 - 0.11 12.2 1.8 0.13 11.9 0.2 1.8 2 0 0 2 2 2 0 Interleukin 11 Fungal_trans PF04082.18 KRZ98643.1 - 9.4e-20 70.7 1.1 2.1e-19 69.6 1.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Med4 PF10018.9 KRZ98643.1 - 0.053 13.2 0.6 0.087 12.5 0.6 1.3 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 MFS_1 PF07690.16 KRZ98644.1 - 4.9e-42 144.1 24.3 4.9e-42 144.1 24.3 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily F_bP_aldolase PF01116.20 KRZ98645.1 - 2.5e-70 237.1 0.0 2.8e-70 237.0 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Amidohydro_1 PF01979.20 KRZ98645.1 - 0.11 11.7 0.1 0.15 11.3 0.1 1.4 1 0 0 1 1 1 0 Amidohydrolase family adh_short PF00106.25 KRZ98646.1 - 5.2e-24 84.8 0.2 6e-24 84.6 0.2 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KRZ98646.1 - 2.9e-19 69.6 0.1 3.4e-19 69.4 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KRZ98646.1 - 9.1e-14 51.8 0.0 1.2e-13 51.4 0.0 1.0 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 KRZ98646.1 - 9.8e-06 24.8 0.0 1.2e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KRZ98646.1 - 4.6e-05 22.7 0.0 5.4e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KRZ98646.1 - 0.0014 18.2 0.1 0.0017 17.9 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KRZ98646.1 - 0.013 15.4 0.1 0.016 15.1 0.1 1.1 1 0 0 1 1 1 0 NAD(P)H-binding Glyco_hydro81C PF17652.1 KRZ98647.1 - 8.6e-149 495.5 9.8 1.1e-148 495.2 9.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 KRZ98647.1 - 4.7e-102 341.5 0.2 7.4e-102 340.8 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain Flavoprotein PF02441.19 KRZ98648.1 - 3.7e-24 85.3 0.1 7.9e-24 84.2 0.0 1.5 2 0 0 2 2 2 1 Flavoprotein UbiD PF01977.16 KRZ98649.1 - 2.2e-103 346.2 0.0 2.5e-103 346.1 0.0 1.0 1 0 0 1 1 1 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase Haem_degrading PF03928.14 KRZ98650.1 - 1.1e-32 112.5 0.0 1.3e-32 112.4 0.0 1.0 1 0 0 1 1 1 1 Haem-degrading XPG_N PF00752.17 KRZ98650.1 - 0.009 16.5 0.0 0.015 15.7 0.0 1.3 1 0 0 1 1 1 1 XPG N-terminal domain MFS_1 PF07690.16 KRZ98651.1 - 1.6e-33 116.1 27.9 8.9e-33 113.7 25.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TSSC4 PF15264.6 KRZ98651.1 - 0.024 14.9 0.0 0.049 13.9 0.0 1.4 1 0 0 1 1 1 0 Tumour suppressing sub-chromosomal transferable candidate 4 CRPA PF05745.11 KRZ98651.1 - 4.6 7.2 12.3 27 4.8 3.5 3.3 3 0 0 3 3 3 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) MFS_1 PF07690.16 KRZ98652.1 - 0.005 15.8 3.8 0.0064 15.5 3.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Cid2 PF09774.9 KRZ98652.1 - 0.033 14.6 0.9 0.049 14.1 0.9 1.2 1 0 0 1 1 1 0 Caffeine-induced death protein 2 TPR_12 PF13424.6 KRZ98653.1 - 0.0012 19.0 13.5 0.035 14.4 0.1 4.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 KRZ98653.1 - 0.0042 17.1 9.8 0.92 9.8 0.1 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat MIT PF04212.18 KRZ98653.1 - 0.04 14.0 1.0 0.12 12.5 0.2 2.3 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_14 PF13428.6 KRZ98653.1 - 0.061 14.2 1.3 3.6 8.6 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 KRZ98653.1 - 0.075 13.7 2.3 1.2 9.9 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Pex14_N PF04695.13 KRZ98653.1 - 0.22 12.2 0.6 0.68 10.6 0.6 1.8 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TPR_1 PF00515.28 KRZ98653.1 - 0.41 10.5 13.6 0.95 9.4 0.3 4.6 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF2034 PF10356.9 KRZ98655.1 - 0.0045 16.4 2.2 0.0045 16.4 2.2 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF2034) zinc_ribbon_2 PF13240.6 KRZ98655.1 - 0.014 15.1 0.6 0.014 15.1 0.6 4.7 7 0 0 7 7 7 0 zinc-ribbon domain Mrr_cat PF04471.12 KRZ98655.1 - 0.023 14.7 0.0 0.023 14.7 0.0 2.2 1 1 1 2 2 2 0 Restriction endonuclease C1_1 PF00130.22 KRZ98655.1 - 0.57 10.1 18.9 0.64 9.9 0.7 4.8 4 1 1 5 5 5 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Indigoidine_A PF04227.12 KRZ98655.1 - 2.2 7.6 10.4 3.5 6.9 10.4 1.3 1 0 0 1 1 1 0 Indigoidine synthase A like protein LMBR1 PF04791.16 KRZ98655.1 - 2.5 6.9 10.1 4.5 6.1 10.1 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF853 PF05872.12 KRZ98655.1 - 2.5 6.6 15.2 3.6 6.1 15.2 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) U1snRNP70_N PF12220.8 KRZ98655.1 - 5.2 7.8 15.2 7.8 7.2 10.5 2.6 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal AAA_23 PF13476.6 KRZ98655.1 - 6 7.3 15.6 1.4 9.3 11.9 1.9 2 0 0 2 2 2 0 AAA domain Pkinase PF00069.25 KRZ98656.1 - 4.2e-60 203.3 0.0 6e-60 202.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KRZ98656.1 - 1.7e-34 119.3 0.0 2.4e-34 118.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KRZ98656.1 - 0.00022 20.1 0.2 0.00043 19.2 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 KRZ98656.1 - 0.0036 16.6 0.0 0.0067 15.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KRZ98656.1 - 0.042 13.5 0.0 0.095 12.3 0.0 1.6 1 1 0 1 1 1 0 RIO1 family Aldolase_II PF00596.21 KRZ98657.1 - 3e-42 144.6 0.1 3.9e-42 144.3 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain MFS_1 PF07690.16 KRZ98659.1 - 1.5e-26 93.2 19.1 1.7e-26 93.0 19.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KRZ98659.1 - 1.2e-10 40.8 7.8 1.7e-10 40.4 7.8 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter DUF1479 PF07350.12 KRZ98660.1 - 1.7e-158 527.8 0.0 2e-158 527.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.13 KRZ98660.1 - 0.0077 16.5 0.0 0.067 13.4 0.0 2.2 2 1 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) Fungal_trans PF04082.18 KRZ98661.1 - 1e-07 31.2 0.1 2e-07 30.3 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ferric_reduct PF01794.19 KRZ98662.1 - 1.3e-23 83.5 14.7 1.3e-23 83.5 14.7 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KRZ98662.1 - 2e-18 66.5 0.4 3.9e-18 65.5 0.4 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 KRZ98662.1 - 1.1e-13 51.6 0.1 2.3e-13 50.6 0.1 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 KRZ98662.1 - 0.0086 16.7 0.0 0.65 10.7 0.0 2.5 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain CFEM PF05730.11 KRZ98662.1 - 0.22 11.6 1.5 0.45 10.6 0.6 1.9 2 0 0 2 2 2 0 CFEM domain Ctr PF04145.15 KRZ98663.1 - 6.7e-22 78.7 2.6 9.3e-22 78.2 2.6 1.2 1 0 0 1 1 1 1 Ctr copper transporter family TMEM223 PF14640.6 KRZ98663.1 - 0.033 14.4 0.2 0.092 12.9 0.0 1.8 1 1 1 2 2 2 0 Transmembrane protein 223 DUF4834 PF16118.5 KRZ98663.1 - 0.73 10.8 0.0 0.73 10.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF4191 PF13829.6 KRZ98663.1 - 1.1 8.5 5.4 0.11 11.8 1.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) F-box-like PF12937.7 KRZ98665.1 - 2e-10 40.4 0.1 8.4e-10 38.4 0.0 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KRZ98665.1 - 3.2e-06 26.9 0.3 6.4e-05 22.7 0.0 3.0 3 0 0 3 3 3 1 F-box domain TFA2_Winged_2 PF18121.1 KRZ98666.1 - 5.8e-22 77.2 0.1 2.1e-21 75.4 0.1 2.0 2 0 0 2 2 2 1 TFA2 Winged helix domain 2 TFIIE_beta PF02186.15 KRZ98666.1 - 8.4e-17 61.2 0.7 2.3e-16 59.9 0.7 1.8 1 0 0 1 1 1 1 TFIIE beta subunit core domain RPA_C PF08784.11 KRZ98666.1 - 0.026 15.2 3.5 0.081 13.6 0.6 2.5 3 0 0 3 3 3 0 Replication protein A C terminal NTF2 PF02136.20 KRZ98667.1 - 3.6e-24 85.6 0.0 4e-24 85.5 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain cwf21 PF08312.12 KRZ98669.1 - 1.8e-13 50.4 6.9 1.8e-13 50.4 6.9 1.7 2 0 0 2 2 2 1 cwf21 domain APG6_N PF17675.1 KRZ98669.1 - 0.25 11.9 11.0 0.36 11.3 11.0 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region V_ATPase_I PF01496.19 KRZ98669.1 - 4.3 5.1 9.2 5.1 4.9 9.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Mannosyl_trans3 PF11051.8 KRZ98670.1 - 2e-79 266.8 1.3 8.9e-79 264.7 0.0 2.2 2 0 0 2 2 2 1 Mannosyltransferase putative Conotoxin PF02950.17 KRZ98670.1 - 0.2 12.7 0.0 0.64 11.1 0.0 1.9 1 0 0 1 1 1 0 Conotoxin CUE PF02845.16 KRZ98671.1 - 4.7e-06 26.2 0.1 0.00026 20.6 0.0 2.6 2 0 0 2 2 2 1 CUE domain DMA PF03474.14 KRZ98671.1 - 0.0016 18.0 0.0 0.74 9.5 0.0 3.4 3 0 0 3 3 3 2 DMRTA motif PH PF00169.29 KRZ98672.1 - 2.3e-22 79.5 13.3 2.8e-11 43.9 1.4 2.3 2 0 0 2 2 2 2 PH domain PH_8 PF15409.6 KRZ98672.1 - 3.8e-09 36.7 9.6 5.5e-05 23.4 3.7 3.1 3 0 0 3 3 3 2 Pleckstrin homology domain PH_11 PF15413.6 KRZ98672.1 - 5.2e-08 33.3 24.4 0.0001 22.7 8.4 4.2 2 2 0 2 2 2 2 Pleckstrin homology domain PH_3 PF14593.6 KRZ98672.1 - 1.2e-05 25.3 11.8 0.016 15.3 3.0 2.8 2 1 0 2 2 2 2 PH domain PH_2 PF08458.10 KRZ98672.1 - 0.00034 20.9 2.0 0.064 13.6 0.3 2.5 2 0 0 2 2 2 2 Plant pleckstrin homology-like region PH_9 PF15410.6 KRZ98672.1 - 0.0066 16.8 11.7 1.7 9.0 3.6 3.8 2 2 0 2 2 2 2 Pleckstrin homology domain Ribosomal_S17 PF00366.20 KRZ98672.1 - 0.016 15.3 0.9 0.11 12.6 0.1 2.8 3 0 0 3 3 3 0 Ribosomal protein S17 BCL_N PF04714.13 KRZ98672.1 - 0.027 14.5 1.3 0.027 14.5 1.3 2.5 2 0 0 2 2 2 0 BCL7, N-terminal conserver region Mcp5_PH PF12814.7 KRZ98672.1 - 0.033 14.3 5.4 0.13 12.3 0.2 2.6 2 1 0 2 2 2 0 Meiotic cell cortex C-terminal pleckstrin homology PH_6 PF15406.6 KRZ98672.1 - 0.047 14.0 0.1 15 5.9 0.1 2.4 2 0 0 2 2 2 0 Pleckstrin homology domain PH_4 PF15404.6 KRZ98672.1 - 0.12 12.1 4.1 0.2 11.4 0.3 2.5 2 1 1 3 3 3 0 Pleckstrin homology domain Rep_fac_C PF08542.11 KRZ98673.1 - 5.9e-14 52.3 0.1 2.7e-13 50.1 0.0 2.1 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 KRZ98673.1 - 2.8e-11 43.5 0.1 2.8e-11 43.5 0.1 2.1 1 1 1 2 2 2 1 DNA polymerase III, delta subunit AAA_assoc_2 PF16193.5 KRZ98673.1 - 3.3e-08 33.7 0.2 8.1e-08 32.5 0.2 1.7 1 0 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 KRZ98673.1 - 2.5e-06 27.9 0.2 4.2e-06 27.2 0.2 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta PF06144.13 KRZ98673.1 - 1.7e-05 24.7 0.8 2.5e-05 24.1 0.8 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit DEAD PF00270.29 KRZ98673.1 - 0.021 14.6 0.0 0.04 13.7 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase DDE_3 PF13358.6 KRZ98673.1 - 0.041 13.7 0.0 0.081 12.7 0.0 1.5 1 0 0 1 1 1 0 DDE superfamily endonuclease Mid1 PF12929.7 KRZ98674.1 - 1.9e-134 449.1 14.9 2.3e-134 448.8 14.9 1.1 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.22 KRZ98674.1 - 0.0009 19.8 8.7 0.037 14.6 8.7 2.6 1 1 0 1 1 1 1 Fz domain Usp PF00582.26 KRZ98675.1 - 0.018 15.6 0.0 0.053 14.0 0.0 1.9 1 1 0 1 1 1 0 Universal stress protein family Vma12 PF11712.8 KRZ98676.1 - 0.81 9.8 2.7 1.9 8.5 0.0 2.2 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Ank_2 PF12796.7 KRZ98677.1 - 6.3e-27 94.0 1.1 9.8e-09 35.7 0.1 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) DHHC PF01529.20 KRZ98677.1 - 6.5e-27 94.3 7.8 6.5e-27 94.3 7.8 2.7 3 1 0 3 3 3 1 DHHC palmitoyltransferase Ank_3 PF13606.6 KRZ98677.1 - 2.5e-21 73.5 4.0 7e-06 26.0 0.1 6.5 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.6 KRZ98677.1 - 5.3e-21 74.7 1.8 3.1e-07 30.8 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KRZ98677.1 - 3.1e-19 68.5 4.8 0.00019 21.7 0.1 5.7 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.6 KRZ98677.1 - 4.5e-18 65.1 3.3 0.002 18.4 0.1 6.4 2 2 4 6 6 6 5 Ankyrin repeats (many copies) DUF4112 PF13430.6 KRZ98678.1 - 6.9e-28 97.0 0.4 9.6e-28 96.5 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) ParE_toxin PF05016.15 KRZ98679.1 - 0.14 12.8 0.0 4.3 8.0 0.0 2.6 2 0 0 2 2 2 0 ParE toxin of type II toxin-antitoxin system, parDE CTP_transf_like PF01467.26 KRZ98681.1 - 4.4e-06 26.9 0.0 8.8e-06 26.0 0.0 1.6 1 1 0 1 1 1 1 Cytidylyltransferase-like SPK PF04435.18 KRZ98681.1 - 0.044 14.2 0.0 0.083 13.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF545) Recep_L_domain PF01030.24 KRZ98682.1 - 6.5e-08 32.7 19.7 0.0022 18.1 0.2 6.0 3 2 2 5 5 5 4 Receptor L domain DUF2487 PF10673.9 KRZ98683.1 - 0.025 14.6 0.5 0.034 14.2 0.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2487) MFS_1 PF07690.16 KRZ98684.1 - 1e-11 44.4 15.3 3.5e-11 42.6 15.3 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Beta-lactamase PF00144.24 KRZ98685.1 - 5.5e-48 163.9 0.0 7.4e-48 163.5 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase NAD_binding_8 PF13450.6 KRZ98686.1 - 1.6e-08 34.7 0.5 1.9e-07 31.2 0.3 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KRZ98686.1 - 0.00058 19.2 0.0 0.00058 19.2 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KRZ98686.1 - 0.15 11.2 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain FMO-like PF00743.19 KRZ98687.1 - 0.00016 20.3 0.0 0.00017 20.2 0.0 1.1 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Shikimate_DH PF01488.20 KRZ98687.1 - 0.0047 17.0 0.0 0.0068 16.5 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase K_oxygenase PF13434.6 KRZ98687.1 - 0.034 13.3 0.0 0.035 13.3 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Fungal_trans PF04082.18 KRZ98689.1 - 3e-12 46.2 0.6 5.3e-12 45.3 0.6 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KRZ98689.1 - 1.1e-08 35.0 10.3 1.9e-08 34.3 10.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RTA1 PF04479.13 KRZ98690.1 - 8.5e-67 224.8 15.9 8.5e-67 224.8 15.9 1.5 2 0 0 2 2 2 1 RTA1 like protein DUF4083 PF13314.6 KRZ98690.1 - 2.7 8.0 17.7 0.57 10.2 0.4 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4083) MFS_1 PF07690.16 KRZ98691.1 - 4.4e-17 62.0 14.9 7e-17 61.4 14.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans PF04082.18 KRZ98692.1 - 2.3e-19 69.5 3.8 1.3e-18 67.0 3.8 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KRZ98692.1 - 0.00016 21.7 13.1 0.00028 20.9 13.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1505 PF07403.11 KRZ98692.1 - 4.2 7.6 9.9 41 4.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1505) Arylsulfotran_2 PF14269.6 KRZ98693.1 - 1.6e-76 257.5 5.7 2.6e-76 256.9 5.7 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KRZ98693.1 - 2.2e-17 63.0 3.9 5.9e-17 61.6 4.0 1.6 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) PQQ PF01011.21 KRZ98693.1 - 0.017 15.1 0.3 0.98 9.5 0.1 3.5 3 0 0 3 3 3 0 PQQ enzyme repeat T4_Rnl2_C PF18043.1 KRZ98694.1 - 0.039 14.1 0.0 0.059 13.5 0.0 1.3 1 0 0 1 1 1 0 T4 RNA ligase 2 C-terminal MFS_1 PF07690.16 KRZ98694.1 - 0.04 12.8 9.8 0.013 14.4 6.3 1.8 2 0 0 2 2 2 0 Major Facilitator Superfamily Dynactin_p22 PF07426.11 KRZ98695.1 - 0.0017 18.2 12.0 0.002 18.0 10.0 2.3 1 1 0 1 1 1 1 Dynactin subunit p22 cwf21 PF08312.12 KRZ98695.1 - 0.024 14.8 0.1 0.07 13.3 0.1 1.8 1 0 0 1 1 1 0 cwf21 domain Syntaxin-6_N PF09177.11 KRZ98695.1 - 0.25 11.9 6.6 0.72 10.5 2.8 3.1 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Pro_isomerase PF00160.21 KRZ98696.1 - 1.2e-50 171.8 0.0 2.4e-50 170.9 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 KRZ98696.1 - 8.8e-06 26.4 0.0 11 7.1 0.0 4.8 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KRZ98696.1 - 1.6e-05 25.1 0.0 7.8 6.9 0.0 4.5 2 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 KRZ98696.1 - 0.0028 17.7 0.1 0.046 13.8 0.0 2.9 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region Colicin PF01024.19 KRZ98696.1 - 0.012 15.5 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 Colicin pore forming domain EAF PF09816.9 KRZ98697.1 - 1.1e-15 57.8 4.5 2.6e-15 56.6 0.0 3.0 2 1 0 2 2 2 1 RNA polymerase II transcription elongation factor SNase PF00565.17 KRZ98698.1 - 2.7e-21 76.1 0.0 3.7e-21 75.6 0.0 1.2 1 0 0 1 1 1 1 Staphylococcal nuclease homologue PGM_PMM_I PF02878.16 KRZ98699.1 - 6.7e-16 58.2 0.0 2.5e-08 33.7 0.0 2.9 1 1 1 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 KRZ98699.1 - 2e-10 40.7 0.2 4.8e-10 39.5 0.2 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_II PF02879.16 KRZ98699.1 - 1.5e-06 28.8 0.5 1.7e-05 25.4 0.1 3.0 3 1 0 3 3 3 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 KRZ98699.1 - 0.013 15.7 0.0 0.028 14.6 0.0 1.7 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III pXO2-72 PF17443.2 KRZ98700.1 - 0.16 12.3 2.0 17 5.8 0.0 2.8 2 1 1 3 3 3 0 Uncharacterized protein pXO2-72 KAR9 PF08580.10 KRZ98701.1 - 3e-161 538.4 27.5 2.2e-158 528.9 27.5 2.0 1 1 0 1 1 1 1 Yeast cortical protein KAR9 RrnaAD PF00398.20 KRZ98702.1 - 3.2e-66 223.1 0.0 3.9e-66 222.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 KRZ98702.1 - 2.8e-06 28.0 0.0 1.4e-05 25.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KRZ98702.1 - 0.00027 21.5 0.0 0.00079 20.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KRZ98702.1 - 0.0018 19.0 0.0 0.0044 17.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KRZ98702.1 - 0.0048 16.2 0.0 0.01 15.1 0.0 1.5 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Virulence_RhuM PF13310.6 KRZ98702.1 - 0.017 14.4 0.1 0.025 13.8 0.1 1.2 1 0 0 1 1 1 0 Virulence protein RhuM family PCMT PF01135.19 KRZ98702.1 - 0.024 14.4 0.0 0.038 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 KRZ98702.1 - 0.06 12.9 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_23 PF13489.6 KRZ98702.1 - 0.068 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DREV PF05219.12 KRZ98702.1 - 0.12 11.4 0.0 0.22 10.6 0.0 1.4 1 0 0 1 1 1 0 DREV methyltransferase DUF4110 PF13422.6 KRZ98703.1 - 8.4e-26 89.9 0.0 8.4e-26 89.9 0.0 2.7 2 1 1 3 3 3 1 Domain of unknown function (DUF4110) SDA1 PF05285.12 KRZ98703.1 - 0.018 14.5 9.2 0.02 14.3 9.2 1.2 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 KRZ98703.1 - 0.048 12.0 5.9 0.05 11.9 5.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Glyco_hydro_2 PF00703.21 KRZ98703.1 - 0.091 13.4 0.3 0.15 12.7 0.3 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 2 DNA_pol_phi PF04931.13 KRZ98703.1 - 2.3 6.2 18.9 2.8 5.9 18.9 1.0 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 KRZ98703.1 - 2.7 6.1 14.8 3.5 5.7 14.8 1.1 1 0 0 1 1 1 0 Nop14-like family CobT PF06213.12 KRZ98703.1 - 6.9 6.0 15.8 9.3 5.6 15.8 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT RRN3 PF05327.11 KRZ98703.1 - 7 5.1 15.6 9.3 4.7 15.6 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Lin-8 PF03353.15 KRZ98703.1 - 7.9 5.9 10.2 13 5.2 10.2 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Transp_cyt_pur PF02133.15 KRZ98704.1 - 5.1e-77 259.5 32.1 6.3e-77 259.2 32.1 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Arginase PF00491.21 KRZ98706.1 - 4.7e-69 233.0 0.0 5.5e-69 232.8 0.0 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 KRZ98706.1 - 0.038 14.2 0.1 0.069 13.4 0.1 1.4 1 0 0 1 1 1 0 UPF0489 domain Sugar_tr PF00083.24 KRZ98707.1 - 3e-64 217.6 25.3 3.7e-64 217.3 25.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KRZ98707.1 - 7.7e-27 94.1 24.4 7.7e-27 94.1 24.4 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KRZ98707.1 - 3.7e-06 25.7 1.0 6.2e-06 24.9 1.0 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Asparaginase PF00710.20 KRZ98708.1 - 1.4e-50 171.5 0.0 1.7e-50 171.2 0.0 1.1 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 KRZ98708.1 - 1.3e-18 67.3 0.0 5.5e-18 65.3 0.0 1.9 2 0 0 2 2 2 1 Glutaminase/Asparaginase C-terminal domain Flocculin_t3 PF13928.6 KRZ98709.1 - 1.7e-06 28.4 9.1 2.5e-06 27.9 9.1 1.3 1 0 0 1 1 1 1 Flocculin type 3 repeat NmrA PF05368.13 KRZ98709.1 - 0.033 13.7 0.0 0.05 13.2 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family NDUF_B4 PF07225.12 KRZ98710.1 - 0.063 13.2 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) 2-Hacid_dh_C PF02826.19 KRZ98711.1 - 3e-42 144.0 0.0 1.9e-41 141.4 0.0 2.2 2 1 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KRZ98711.1 - 2.9e-20 72.3 0.0 3.8e-20 71.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Shikimate_DH PF01488.20 KRZ98711.1 - 0.099 12.7 0.2 1.1 9.3 0.0 2.4 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Arginase PF00491.21 KRZ98712.1 - 8.1e-17 61.6 0.0 9.3e-17 61.4 0.0 1.0 1 0 0 1 1 1 1 Arginase family Fungal_trans PF04082.18 KRZ98713.1 - 1.3e-14 53.9 6.3 3.2e-14 52.6 6.3 1.8 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KRZ98713.1 - 5.9e-08 32.7 12.6 1.2e-07 31.7 12.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HSP70 PF00012.20 KRZ98714.1 - 1.1e-258 859.4 16.3 1.3e-258 859.2 16.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KRZ98714.1 - 6.5e-20 71.2 2.5 4.5e-19 68.4 1.0 2.2 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 KRZ98714.1 - 0.005 17.2 6.0 3.3 8.2 0.0 3.5 3 1 0 3 3 3 2 Cell division protein FtsA DUF1464 PF07318.12 KRZ98714.1 - 0.0085 15.3 1.6 0.54 9.3 0.0 3.1 2 1 1 3 3 3 1 Protein of unknown function (DUF1464) DDR PF08841.10 KRZ98714.1 - 0.0089 15.1 1.7 0.065 12.2 1.0 2.2 1 1 0 1 1 1 1 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.18 KRZ98714.1 - 0.01 15.1 2.2 0.073 12.3 0.3 2.5 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase Sec6 PF06046.13 KRZ98714.1 - 0.049 12.0 2.8 0.16 10.3 0.7 2.2 2 0 0 2 2 2 0 Exocyst complex component Sec6 RdRP_2 PF00978.21 KRZ98714.1 - 0.23 10.3 2.9 0.74 8.6 0.1 2.5 3 0 0 3 3 3 0 RNA dependent RNA polymerase Med5 PF08689.10 KRZ98715.1 - 1.5e-82 278.1 33.9 3.1e-82 277.0 33.9 1.5 1 1 0 1 1 1 1 Mediator complex subunit Med5 AA_permease_2 PF13520.6 KRZ98716.1 - 4.3e-23 81.8 16.0 5.6e-23 81.5 16.0 1.1 1 0 0 1 1 1 1 Amino acid permease Mem_trans PF03547.18 KRZ98716.1 - 0.37 9.1 5.7 0.59 8.5 5.7 1.3 1 0 0 1 1 1 0 Membrane transport protein DUF485 PF04341.12 KRZ98716.1 - 1.5 8.8 11.5 0.86 9.6 0.5 3.1 3 0 0 3 3 3 0 Protein of unknown function, DUF485 AA_permease_2 PF13520.6 KRZ98717.1 - 7.8e-24 84.3 26.3 8.8e-24 84.1 26.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KRZ98717.1 - 0.0013 17.4 19.0 0.0016 17.1 19.0 1.1 1 0 0 1 1 1 1 Amino acid permease VIT1 PF01988.19 KRZ98717.1 - 0.0096 15.8 1.2 0.014 15.3 0.2 1.6 1 1 0 1 1 1 1 VIT family DUF2975 PF11188.8 KRZ98717.1 - 6.4 6.7 11.0 8.2 6.3 5.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) DUF1218 PF06749.12 KRZ98717.1 - 7.5 7.2 10.8 2.2 8.9 3.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) DNA_pol_B PF00136.21 KRZ98718.1 - 7.6e-153 509.5 4.3 1e-152 509.0 4.3 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 KRZ98718.1 - 2.6e-84 283.2 2.7 4.2e-84 282.6 2.7 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 KRZ98718.1 - 9.1e-19 67.7 7.8 2.2e-18 66.4 7.8 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 KRZ98718.1 - 0.0045 15.9 8.0 0.039 12.8 0.2 3.4 3 1 1 4 4 4 1 DNA polymerase type B, organellar and viral DNA_pol_B_exo2 PF10108.9 KRZ98718.1 - 0.014 15.1 0.0 0.026 14.2 0.0 1.5 1 0 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 KRZ98718.1 - 0.016 15.2 0.2 0.12 12.3 0.2 2.4 1 1 0 1 1 1 0 RNase_H superfamily DZR PF12773.7 KRZ98718.1 - 1.5 8.9 8.4 0.064 13.3 1.0 2.1 2 0 0 2 2 2 0 Double zinc ribbon C1_1 PF00130.22 KRZ98718.1 - 2.2 8.3 8.6 6.2 6.8 1.4 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) HAMP PF00672.25 KRZ98719.1 - 9.8e-34 115.5 13.2 5.8e-09 36.2 1.1 6.3 6 0 0 6 6 6 5 HAMP domain HATPase_c PF02518.26 KRZ98719.1 - 9.3e-30 103.4 0.1 2.3e-29 102.2 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KRZ98719.1 - 1e-25 90.1 0.2 5.7e-25 87.7 0.2 2.4 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KRZ98719.1 - 3.1e-18 65.6 1.4 2.6e-17 62.6 0.7 3.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain DUF4279 PF14106.6 KRZ98719.1 - 0.027 14.7 0.2 4.9 7.4 0.0 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4279) IL32 PF15225.6 KRZ98719.1 - 0.073 13.4 0.2 51 4.3 0.0 3.8 4 0 0 4 4 4 0 Interleukin 32 DUF3829 PF12889.7 KRZ98719.1 - 0.13 11.7 13.8 0.17 11.3 0.4 4.8 5 1 0 5 5 5 0 Protein of unknown function (DUF3829) DUF1843 PF08898.10 KRZ98719.1 - 0.14 12.7 5.8 14 6.3 0.0 4.5 5 0 0 5 5 5 0 Domain of unknown function (DUF1843) Phage_holin_6_1 PF09682.10 KRZ98719.1 - 0.41 11.1 7.1 0.48 10.9 1.0 3.2 2 0 0 2 2 2 0 Bacteriophage holin of superfamily 6 (Holin_LLH) Sec7 PF01369.20 KRZ98720.1 - 6.9e-70 234.5 0.3 6.9e-70 234.5 0.3 3.0 4 0 0 4 4 4 1 Sec7 domain Sec7_N PF12783.7 KRZ98720.1 - 1.9e-42 144.9 5.0 1.9e-42 144.9 5.0 4.4 5 0 0 5 5 5 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 KRZ98720.1 - 3.2e-34 116.6 1.9 3.2e-34 116.6 1.9 5.1 6 0 0 6 6 6 1 Domain of unknown function (DUF1981) DCB PF16213.5 KRZ98720.1 - 2e-06 27.6 10.3 8.8e-06 25.5 2.3 3.2 2 1 0 2 2 2 2 Dimerisation and cyclophilin-binding domain of Mon2 ComC PF03047.14 KRZ98720.1 - 0.61 9.9 4.0 0.49 10.3 1.0 2.5 2 0 0 2 2 2 0 COMC family RIH_assoc PF08454.11 KRZ98720.1 - 1.7 8.5 8.1 1.4 8.8 1.3 4.1 4 0 0 4 4 4 0 RyR and IP3R Homology associated FAS_I_H PF18314.1 KRZ98721.1 - 9.4e-75 250.7 4.8 1e-74 250.6 0.7 2.6 2 0 0 2 2 2 1 Fatty acid synthase type I helical domain Fas_alpha_ACP PF18325.1 KRZ98721.1 - 6.4e-73 244.4 0.0 1.7e-72 243.0 0.0 1.8 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain ketoacyl-synt PF00109.26 KRZ98721.1 - 1.3e-20 74.0 0.0 2.5e-20 73.2 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.20 KRZ98721.1 - 9.1e-18 64.5 0.0 2.5e-17 63.1 0.0 1.7 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.22 KRZ98721.1 - 2.1e-11 43.9 0.0 6e-11 42.4 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.25 KRZ98721.1 - 4.8e-05 22.9 0.0 0.00011 21.7 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KRZ98721.1 - 0.011 15.7 0.0 0.029 14.3 0.0 1.7 1 0 0 1 1 1 0 KR domain F420_oxidored PF03807.17 KRZ98721.1 - 0.028 15.0 1.1 0.24 12.0 0.1 2.8 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent DUF2340 PF10209.9 KRZ98722.1 - 4.9e-53 178.7 0.3 5.8e-53 178.4 0.3 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) Ras PF00071.22 KRZ98724.1 - 2.1e-22 79.5 0.0 2.5e-22 79.2 0.0 1.1 1 0 0 1 1 1 1 Ras family DUF3128 PF11326.8 KRZ98725.1 - 1.1e-23 83.4 1.4 1.9e-23 82.6 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3128) Ribosomal_L27A PF00828.19 KRZ98726.1 - 1.5e-26 93.6 0.3 2.5e-26 92.8 0.1 1.5 2 0 0 2 2 2 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Sld7_C PF18596.1 KRZ98727.1 - 3.3e-25 88.0 0.2 6.7e-25 87.0 0.2 1.5 1 0 0 1 1 1 1 Sld7 C-terminal domain Sld7_N PF18636.1 KRZ98727.1 - 1.2e-07 32.0 0.1 3e-07 30.8 0.1 1.6 1 0 0 1 1 1 1 Mitochondrial morphogenesis protein SLD7 N-terminal domain Pkinase PF00069.25 KRZ98728.1 - 6.1e-59 199.5 0.1 7.3e-59 199.3 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KRZ98728.1 - 7.7e-16 58.2 0.0 1.6e-15 57.1 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KRZ98728.1 - 4.7e-05 23.4 0.0 8.4e-05 22.6 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KRZ98728.1 - 0.017 14.7 0.1 0.036 13.6 0.1 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 KRZ98728.1 - 0.12 11.1 0.1 0.2 10.4 0.1 1.3 1 0 0 1 1 1 0 Fungal protein kinase CH PF00307.31 KRZ98729.1 - 9.4e-23 80.5 7.4 2.9e-15 56.4 1.0 3.6 2 1 0 2 2 2 2 Calponin homology (CH) domain Voltage_CLC PF00654.20 KRZ98731.1 - 4.6e-82 276.1 17.6 4.6e-82 276.1 17.6 2.1 2 0 0 2 2 2 1 Voltage gated chloride channel DUF4203 PF13886.6 KRZ98731.1 - 0.022 14.5 0.1 0.022 14.5 0.1 4.9 4 1 2 6 6 6 0 Domain of unknown function (DUF4203) F-actin_cap_A PF01267.17 KRZ98732.1 - 0.76 9.2 6.1 3.7 6.9 6.1 1.9 1 1 0 1 1 1 0 F-actin capping protein alpha subunit MT-A70 PF05063.14 KRZ98733.1 - 8.5e-11 42.1 0.1 2.2e-10 40.7 0.0 1.7 2 0 0 2 2 2 1 MT-A70 Iso_dh PF00180.20 KRZ98734.1 - 3.4e-72 243.5 0.0 3.9e-72 243.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase mRNA_triPase PF02940.15 KRZ98735.1 - 7.1e-65 218.8 1.9 1.4e-64 217.8 1.9 1.5 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain Noggin PF05806.12 KRZ98735.1 - 0.018 15.0 0.4 0.036 14.0 0.4 1.4 1 0 0 1 1 1 0 Noggin Glycos_transf_2 PF00535.26 KRZ98736.1 - 1e-23 84.0 0.0 1.4e-23 83.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KRZ98736.1 - 2.7e-08 34.0 0.0 3.2e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 KRZ98736.1 - 0.0046 17.4 0.0 0.0082 16.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 KRZ98736.1 - 0.0067 15.9 0.0 0.0091 15.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Bmt2 PF11968.8 KRZ98736.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Class_IIIsignal PF04021.12 KRZ98736.1 - 0.81 9.7 7.8 1.4 9.0 7.8 1.4 1 0 0 1 1 1 0 Class III signal peptide RICTOR_N PF14664.6 KRZ98737.1 - 4.7e-117 391.1 13.8 4.7e-117 391.1 13.8 2.1 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.6 KRZ98737.1 - 4.6e-29 100.2 10.0 4.1e-27 94.0 0.6 5.4 5 1 0 5 5 5 2 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_V PF14668.6 KRZ98737.1 - 1.6e-25 89.1 13.9 1.8e-25 88.9 0.5 6.4 7 0 0 7 7 7 1 Rapamycin-insensitive companion of mTOR, domain 5 RasGEF_N_2 PF14663.6 KRZ98737.1 - 2.8e-25 88.8 6.5 4.2e-24 85.0 0.1 4.7 5 0 0 5 5 5 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain Herpes_Helicase PF02689.14 KRZ98738.1 - 0.011 13.7 1.1 0.014 13.3 1.1 1.1 1 0 0 1 1 1 0 Helicase DUF2358 PF10184.9 KRZ98738.1 - 0.16 12.2 1.1 0.29 11.4 1.1 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2358) O-antigen_lig PF13425.6 KRZ98738.1 - 7.3 5.3 8.1 9.6 4.9 8.1 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein ASF1_hist_chap PF04729.13 KRZ98739.1 - 2e-71 239.0 1.5 2.5e-71 238.6 0.0 1.8 2 0 0 2 2 2 1 ASF1 like histone chaperone Collagen PF01391.18 KRZ98739.1 - 0.0033 17.1 1.5 0.0053 16.5 1.5 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) DUF3245 PF11595.8 KRZ98740.1 - 0.052 14.0 2.7 0.14 12.6 2.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) RXT2_N PF08595.11 KRZ98740.1 - 1.2 9.1 7.7 0.5 10.4 2.5 2.5 2 0 0 2 2 2 0 RXT2-like, N-terminal PP1_bind PF15276.6 KRZ98740.1 - 5.3 7.4 0.0 5.3 7.4 0.0 3.8 4 0 0 4 4 4 0 Protein phosphatase 1 binding Importin_rep_4 PF18808.1 KRZ98740.1 - 6.2 7.2 7.2 0.65 10.3 2.0 2.1 2 0 0 2 2 2 0 Importin repeat NOA36 PF06524.12 KRZ98740.1 - 6.7 5.9 7.4 3 7.1 2.3 2.2 2 0 0 2 2 2 0 NOA36 protein Mem_trans PF03547.18 KRZ98741.1 - 4.2e-63 213.1 2.0 5.5e-63 212.7 2.0 1.1 1 0 0 1 1 1 1 Membrane transport protein Ras PF00071.22 KRZ98742.1 - 1.3e-49 167.9 0.8 1.5e-49 167.7 0.8 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KRZ98742.1 - 9.4e-17 61.4 0.0 1.4e-16 60.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KRZ98742.1 - 2.2e-06 27.2 0.1 2.4e-06 27.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KRZ98742.1 - 1e-05 25.2 0.2 3.1e-05 23.6 0.1 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KRZ98742.1 - 6.1e-05 23.0 0.7 0.0017 18.2 0.1 2.1 1 1 1 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 KRZ98742.1 - 0.00054 20.0 0.1 0.00087 19.3 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_14 PF13173.6 KRZ98742.1 - 0.045 13.8 0.1 0.06 13.4 0.1 1.4 1 1 0 1 1 1 0 AAA domain Ribosomal_L19e PF01280.20 KRZ98743.1 - 1.7e-59 200.0 8.8 1.7e-59 200.0 8.8 1.9 2 0 0 2 2 2 1 Ribosomal protein L19e CsgA PF17334.2 KRZ98743.1 - 0.17 12.7 1.5 0.29 11.9 1.5 1.4 1 0 0 1 1 1 0 Minor curli fiber component A RGS PF00615.19 KRZ98744.1 - 1.5e-06 28.5 0.1 0.00014 22.1 0.1 2.5 2 0 0 2 2 2 2 Regulator of G protein signaling domain zf-C2H2_4 PF13894.6 KRZ98745.1 - 2.3e-05 24.8 11.3 0.0011 19.6 2.1 3.8 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2 PF00096.26 KRZ98745.1 - 0.00037 20.8 2.9 0.00037 20.8 2.9 3.5 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KRZ98745.1 - 0.047 14.1 13.4 0.058 13.9 0.8 3.2 3 0 0 3 3 3 0 Zinc-finger double domain CpXC PF14353.6 KRZ98745.1 - 0.068 13.2 0.2 0.14 12.2 0.2 1.6 1 0 0 1 1 1 0 CpXC protein zinc_ribbon_5 PF13719.6 KRZ98745.1 - 0.096 12.5 0.5 0.44 10.4 0.0 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-Di19 PF05605.12 KRZ98745.1 - 0.13 12.6 4.5 0.31 11.4 3.6 2.1 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.6 KRZ98745.1 - 0.37 10.6 10.7 0.043 13.6 5.0 2.6 2 1 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2_3rep PF18868.1 KRZ98745.1 - 0.45 11.2 2.8 3 8.5 1.0 2.5 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats SPA PF08616.10 KRZ98747.1 - 7.4e-34 116.1 0.5 2.4e-33 114.5 0.1 2.1 2 0 0 2 2 2 1 Stabilization of polarity axis Afi1 PF07792.12 KRZ98747.1 - 2.5e-21 76.6 0.2 6.3e-21 75.3 0.1 1.8 2 0 0 2 2 2 1 Docking domain of Afi1 for Arf3 in vesicle trafficking Avl9 PF09794.9 KRZ98747.1 - 1.9e-12 46.6 3.8 1.3e-09 37.3 0.1 2.7 2 1 1 3 3 3 2 Transport protein Avl9 DENN PF02141.21 KRZ98747.1 - 0.017 15.0 4.1 2.6 7.9 0.1 3.8 3 1 0 3 3 3 0 DENN (AEX-3) domain Mito_carr PF00153.27 KRZ98749.1 - 1.1e-49 166.3 4.2 3.1e-16 59.1 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein HMD PF03201.16 KRZ98749.1 - 0.048 13.9 0.3 2.2 8.5 0.1 3.1 3 0 0 3 3 3 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase DUF468 PF04318.12 KRZ98749.1 - 0.18 12.5 1.3 0.47 11.2 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF468) DUF3020 PF11223.8 KRZ98749.1 - 3 8.4 7.6 1.2 9.7 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3020) ABC2_membrane PF01061.24 KRZ98750.1 - 1.7e-35 122.4 13.2 1.7e-35 122.4 13.2 1.8 3 0 0 3 3 3 1 ABC-2 type transporter ABC_tran PF00005.27 KRZ98750.1 - 9.5e-28 97.4 0.0 2.1e-27 96.3 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 KRZ98750.1 - 7.8e-05 21.9 24.2 7.8e-05 21.9 24.2 2.5 2 2 0 2 2 2 1 ABC-2 family transporter protein AAA_21 PF13304.6 KRZ98750.1 - 0.00042 20.2 6.2 0.17 11.6 0.0 3.1 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system Rad17 PF03215.15 KRZ98750.1 - 0.0012 18.8 0.0 0.0055 16.6 0.0 2.2 1 0 0 1 1 1 1 Rad17 P-loop domain RsgA_GTPase PF03193.16 KRZ98750.1 - 0.0045 16.9 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 KRZ98750.1 - 0.022 14.5 0.0 0.05 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 KRZ98750.1 - 0.07 13.4 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 KRZ98750.1 - 0.079 12.0 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_28 PF13521.6 KRZ98750.1 - 0.14 12.4 0.4 0.23 11.7 0.4 1.3 1 0 0 1 1 1 0 AAA domain EGF_alliinase PF04863.13 KRZ98750.1 - 7.5 7.0 15.7 1.6 9.2 4.8 2.8 2 0 0 2 2 2 0 Alliinase EGF-like domain UCH PF00443.29 KRZ98751.1 - 3e-32 112.1 2.3 3.7e-32 111.8 2.3 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Baculo_PEP_C PF04513.12 KRZ98751.1 - 0.028 14.5 0.8 0.065 13.3 0.8 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Csm1_N PF18504.1 KRZ98751.1 - 0.035 14.5 6.2 0.22 11.9 0.5 3.0 3 0 0 3 3 3 0 Csm1 N-terminal domain Osmo_CC PF08946.10 KRZ98751.1 - 0.5 10.7 3.3 0.49 10.7 0.3 2.7 2 0 0 2 2 2 0 Osmosensory transporter coiled coil DUF1664 PF07889.12 KRZ98751.1 - 1.4 9.0 5.9 0.23 11.5 1.1 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Fez1 PF06818.15 KRZ98751.1 - 7.2 7.0 7.7 4.8 7.6 3.2 2.6 2 1 0 2 2 2 0 Fez1 RPT PF13446.6 KRZ98752.1 - 2.2e-51 171.6 10.2 7.9e-16 57.7 0.2 4.6 4 0 0 4 4 4 4 A repeated domain in UCH-protein UCH PF00443.29 KRZ98752.1 - 5.3e-09 35.9 0.4 2.1e-08 34.0 0.1 2.1 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KRZ98752.1 - 0.00046 19.9 0.1 0.00091 18.9 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase BCS1_N PF08740.11 KRZ98753.1 - 4.5e-46 157.2 0.0 1.5e-45 155.5 0.0 1.7 2 0 0 2 2 2 1 BCS1 N terminal AAA PF00004.29 KRZ98753.1 - 2.8e-22 79.5 0.0 4.8e-22 78.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KRZ98753.1 - 0.0019 18.0 0.0 0.0032 17.2 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 KRZ98753.1 - 0.0023 17.1 0.0 0.0038 16.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 KRZ98753.1 - 0.0028 18.1 0.0 0.0068 16.8 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 KRZ98753.1 - 0.0065 17.0 0.0 0.013 16.0 0.0 1.7 1 1 0 1 1 1 1 ABC transporter AAA_18 PF13238.6 KRZ98753.1 - 0.0075 16.8 0.1 0.023 15.2 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_5 PF07728.14 KRZ98753.1 - 0.0076 16.3 0.0 0.021 14.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 KRZ98753.1 - 0.012 15.3 0.0 0.035 13.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 KRZ98753.1 - 0.013 15.0 0.0 0.024 14.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 KRZ98753.1 - 0.021 14.6 0.0 0.031 14.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KRZ98753.1 - 0.021 15.0 0.0 0.039 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 KRZ98753.1 - 0.028 14.3 0.0 0.052 13.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system ATPase PF06745.13 KRZ98753.1 - 0.033 13.5 0.0 0.07 12.5 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_23 PF13476.6 KRZ98753.1 - 0.034 14.7 0.0 0.2 12.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KRZ98753.1 - 0.048 13.6 0.0 0.094 12.6 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 KRZ98753.1 - 0.065 13.6 0.0 0.2 12.1 0.0 1.9 1 0 0 1 1 1 0 RNA helicase TsaE PF02367.17 KRZ98753.1 - 0.07 13.1 0.0 0.28 11.2 0.0 1.9 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 KRZ98753.1 - 0.074 13.0 0.0 0.2 11.5 0.0 1.7 1 1 1 2 2 2 0 NACHT domain AAA_22 PF13401.6 KRZ98753.1 - 0.12 12.6 0.0 0.42 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KRZ98753.1 - 0.16 11.7 0.0 2.9 7.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 KRZ98753.1 - 0.17 11.7 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain CENP-W PF15510.6 KRZ98754.1 - 0.00056 20.1 0.0 0.00062 19.9 0.0 1.0 1 0 0 1 1 1 1 CENP-W protein Antimicrobial_7 PF08102.11 KRZ98754.1 - 0.1 12.8 0.0 0.24 11.7 0.0 1.5 1 0 0 1 1 1 0 Scorpion antimicrobial peptide HSF_DNA-bind PF00447.17 KRZ98755.1 - 5.2e-30 103.9 2.4 7.6e-30 103.4 0.6 2.3 2 0 0 2 2 2 1 HSF-type DNA-binding SRF-TF PF00319.18 KRZ98756.1 - 3.3e-21 74.5 0.1 5.7e-21 73.8 0.1 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Med19 PF10278.9 KRZ98756.1 - 0.32 10.9 8.2 0.9 9.4 8.2 1.7 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Ribosomal_S6e PF01092.19 KRZ98757.1 - 2.2e-45 153.6 0.2 4.5e-45 152.6 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein S6e DUF4574 PF15141.6 KRZ98757.1 - 0.16 11.9 5.7 0.28 11.1 5.7 1.3 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 VKG_Carbox PF05090.14 KRZ98757.1 - 0.17 10.7 0.5 0.22 10.3 0.5 1.1 1 0 0 1 1 1 0 Vitamin K-dependent gamma-carboxylase PRP21_like_P PF12230.8 KRZ98758.1 - 1.5e-66 224.4 8.4 2.3e-66 223.8 8.4 1.3 1 0 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 KRZ98758.1 - 1.9e-30 104.6 5.9 2.2e-15 56.4 0.2 2.6 2 0 0 2 2 2 2 Surp module zinc_ribbon_6 PF14599.6 KRZ98759.1 - 5.2e-24 84.0 0.6 5.2e-24 84.0 0.6 3.8 3 1 0 3 3 3 1 Zinc-ribbon zf-CHY PF05495.12 KRZ98759.1 - 5.8e-17 61.9 21.2 5.8e-17 61.9 21.2 3.7 3 1 0 3 3 3 1 CHY zinc finger zf-RING_2 PF13639.6 KRZ98759.1 - 6e-07 29.7 8.3 6e-07 29.7 8.3 5.6 4 1 2 6 6 6 1 Ring finger domain Prok-RING_4 PF14447.6 KRZ98759.1 - 3e-05 23.8 1.6 3e-05 23.8 1.6 4.8 2 2 2 4 4 4 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KRZ98759.1 - 3.7e-05 23.5 7.4 3.7e-05 23.5 7.4 4.7 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KRZ98759.1 - 0.00018 21.3 10.5 0.00018 21.3 10.5 6.1 3 2 3 6 6 6 2 Zinc finger, C3HC4 type (RING finger) DZR PF12773.7 KRZ98759.1 - 0.0023 17.9 9.0 0.0023 17.9 9.0 5.0 2 2 1 3 3 3 2 Double zinc ribbon NIF PF03031.18 KRZ98760.1 - 2.1e-44 151.1 0.1 5.5e-43 146.4 0.1 2.2 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase Ric8 PF10165.9 KRZ98761.1 - 0.00079 18.6 0.9 0.0013 17.8 0.9 1.3 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn Nrap_D5 PF17406.2 KRZ98762.1 - 3.1e-51 173.3 0.0 6.9e-51 172.2 0.0 1.6 1 0 0 1 1 1 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D2 PF17403.2 KRZ98762.1 - 1.2e-50 171.2 0.1 4.9e-49 166.0 0.0 2.5 2 0 0 2 2 2 1 Nrap protein PAP/OAS-like domain Nrap_D4 PF17405.2 KRZ98762.1 - 1.8e-50 171.3 0.2 3e-50 170.5 0.2 1.3 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap PF03813.14 KRZ98762.1 - 8.8e-45 152.5 2.3 2.9e-44 150.8 2.3 2.0 1 0 0 1 1 1 1 Nrap protein domain 1 Nrap_D3 PF17404.2 KRZ98762.1 - 1.8e-42 145.1 0.0 4.4e-42 143.9 0.0 1.7 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap_D6 PF17407.2 KRZ98762.1 - 6.7e-31 107.3 1.6 9.8e-31 106.8 0.4 2.0 2 0 0 2 2 2 1 Nrap protein domain 6 GCIP PF13324.6 KRZ98762.1 - 0.0015 18.2 4.6 0.0028 17.3 4.6 1.3 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting DUF4611 PF15387.6 KRZ98762.1 - 0.026 14.8 10.6 0.057 13.7 10.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) ORC_WH_C PF18137.1 KRZ98762.1 - 0.3 11.1 4.9 1.9 8.5 3.9 2.4 2 0 0 2 2 2 0 Origin recognition complex winged helix C-terminal Pox_Ag35 PF03286.14 KRZ98762.1 - 1.2 8.9 10.3 2.2 8.0 10.3 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein PBP1_TM PF14812.6 KRZ98762.1 - 2.5 8.5 7.3 4.9 7.6 7.3 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SQHop_cyclase_C PF13243.6 KRZ98763.1 - 3e-46 158.0 0.4 1.1e-44 152.9 0.2 2.2 2 0 0 2 2 2 1 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 KRZ98763.1 - 3.6e-36 124.8 0.1 3e-30 105.3 0.0 3.4 2 1 2 4 4 4 3 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 KRZ98763.1 - 3.6e-25 87.4 1.3 7.2e-08 32.0 0.1 3.8 3 0 0 3 3 3 3 Prenyltransferase and squalene oxidase repeat Pec_lyase PF09492.10 KRZ98763.1 - 1.1e-06 28.2 4.9 0.035 13.4 0.8 4.5 4 1 1 5 5 5 3 Pectic acid lyase TED_complement PF07678.14 KRZ98763.1 - 0.00011 21.4 1.0 0.059 12.4 0.3 3.1 2 1 1 3 3 3 2 A-macroglobulin TED domain Amidohydro_1 PF01979.20 KRZ98764.1 - 3.5e-33 115.4 0.0 6.4e-16 58.6 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 KRZ98764.1 - 4.9e-09 36.2 0.0 0.00036 20.1 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family ADH_zinc_N PF00107.26 KRZ98765.1 - 8.3e-13 48.4 0.0 1.3e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KRZ98765.1 - 0.00031 21.8 0.0 0.00058 20.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KRZ98765.1 - 0.0051 16.7 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Mpv17_PMP22 PF04117.12 KRZ98766.1 - 0.00019 21.6 1.7 0.00025 21.2 0.4 1.8 2 0 0 2 2 2 1 Mpv17 / PMP22 family Sugar_tr PF00083.24 KRZ98767.1 - 2.2e-125 419.1 19.2 3e-125 418.6 19.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KRZ98767.1 - 4.4e-28 98.2 52.3 1.8e-23 83.0 24.4 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KRZ98767.1 - 0.0093 14.4 0.9 0.0093 14.4 0.9 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) PRK PF00485.18 KRZ98768.1 - 2.8e-05 23.9 0.0 3.8e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family NB-ARC PF00931.22 KRZ98768.1 - 2.9e-05 23.4 0.6 8.6e-05 21.8 0.0 1.8 2 0 0 2 2 2 1 NB-ARC domain AAA_18 PF13238.6 KRZ98768.1 - 0.0001 22.9 0.1 0.00036 21.1 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KRZ98768.1 - 0.00026 21.2 0.0 0.00055 20.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KRZ98768.1 - 0.00036 19.9 0.0 0.03 13.6 0.0 2.8 3 0 0 3 3 3 1 Zeta toxin AAA_16 PF13191.6 KRZ98768.1 - 0.0014 19.0 0.0 0.0027 18.1 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain Torsin PF06309.11 KRZ98768.1 - 0.004 17.2 0.1 0.022 14.9 0.0 2.1 3 0 0 3 3 3 1 Torsin MeaB PF03308.16 KRZ98768.1 - 0.0048 15.9 0.0 0.0067 15.4 0.0 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Viral_helicase1 PF01443.18 KRZ98768.1 - 0.0098 15.7 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_17 PF13207.6 KRZ98768.1 - 0.014 15.8 0.4 0.08 13.4 0.2 2.2 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KRZ98768.1 - 0.015 15.3 0.1 0.028 14.3 0.1 1.4 1 0 0 1 1 1 0 NTPase CbiA PF01656.23 KRZ98768.1 - 0.024 14.7 0.4 0.049 13.7 0.3 1.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_19 PF13245.6 KRZ98768.1 - 0.026 14.8 0.0 0.077 13.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 KRZ98768.1 - 0.027 14.4 0.0 0.044 13.7 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 6PF2K PF01591.18 KRZ98768.1 - 0.032 13.5 0.0 0.05 12.9 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA PF00004.29 KRZ98768.1 - 0.033 14.6 0.0 0.058 13.8 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 KRZ98768.1 - 0.093 12.1 0.0 2 7.7 0.0 2.2 2 0 0 2 2 2 0 KaiC APS_kinase PF01583.20 KRZ98768.1 - 0.097 12.6 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase KTI12 PF08433.10 KRZ98768.1 - 0.1 12.0 0.1 0.29 10.6 0.0 1.8 2 0 0 2 2 2 0 Chromatin associated protein KTI12 RNA_helicase PF00910.22 KRZ98768.1 - 0.11 12.9 0.0 0.26 11.7 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.6 KRZ98768.1 - 0.14 11.9 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Fungal_trans PF04082.18 KRZ98769.1 - 6.6e-18 64.7 0.6 1.9e-17 63.2 0.6 1.9 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KRZ98769.1 - 1.9e-10 40.7 10.2 3.6e-10 39.8 10.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.13 KRZ98769.1 - 2e-10 40.6 4.4 3.8e-09 36.6 0.1 3.0 2 0 0 2 2 2 1 Gal4-like dimerisation domain EF1_GNE PF00736.19 KRZ98770.1 - 1.8e-31 108.2 2.9 2.8e-31 107.6 0.7 2.1 2 0 0 2 2 2 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 KRZ98770.1 - 2.1e-13 50.4 4.8 2.1e-13 50.4 4.8 2.9 4 0 0 4 4 4 1 Eukaryotic elongation factor 1 beta central acidic region YL1 PF05764.13 KRZ98770.1 - 0.035 14.2 1.2 0.043 13.9 1.2 1.3 1 0 0 1 1 1 0 YL1 nuclear protein GST_C_6 PF17171.4 KRZ98770.1 - 0.051 13.4 0.0 0.099 12.5 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain CBM46 PF18448.1 KRZ98770.1 - 0.089 13.1 0.1 1.3 9.4 0.1 2.2 2 0 0 2 2 2 0 Carbohydrate binding domain N6-adenineMlase PF10237.9 KRZ98771.1 - 2.4e-50 170.5 0.2 3e-50 170.2 0.2 1.1 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase B-block_TFIIIC PF04182.12 KRZ98772.1 - 4.5e-23 81.2 0.8 1.4e-20 73.2 0.0 3.4 3 0 0 3 3 3 2 B-block binding subunit of TFIIIC MarR_2 PF12802.7 KRZ98772.1 - 0.02 14.8 0.0 0.081 12.8 0.0 2.0 2 0 0 2 2 2 0 MarR family AT_hook PF02178.19 KRZ98772.1 - 0.095 12.6 3.7 0.33 11.0 3.7 1.9 1 0 0 1 1 1 0 AT hook motif G-patch PF01585.23 KRZ98773.1 - 1.3e-12 47.4 0.2 2.9e-12 46.3 0.2 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KRZ98773.1 - 7.6e-05 22.7 0.1 7.6e-05 22.7 0.1 1.7 2 0 0 2 2 2 1 G-patch domain FeoA PF04023.14 KRZ98773.1 - 0.081 13.2 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 FeoA domain Histone PF00125.24 KRZ98774.1 - 6.2e-21 75.1 3.4 7.4e-21 74.9 3.4 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KRZ98774.1 - 2.5e-07 30.9 0.1 6e-07 29.7 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone YscO-like PF16789.5 KRZ98774.1 - 0.0036 17.3 0.4 0.0043 17.1 0.4 1.1 1 0 0 1 1 1 1 YscO-like protein TFIID_20kDa PF03847.13 KRZ98774.1 - 0.0055 17.2 0.0 0.0095 16.4 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CENP-W PF15510.6 KRZ98774.1 - 0.022 14.9 0.0 0.035 14.3 0.0 1.2 1 0 0 1 1 1 0 CENP-W protein Histone_H2A_C PF16211.5 KRZ98775.1 - 4.7e-20 71.0 1.3 7.9e-20 70.3 1.3 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KRZ98775.1 - 5.2e-17 62.4 0.0 6.7e-17 62.1 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KRZ98775.1 - 8.7e-06 25.9 0.0 1.2e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Acyltransferase PF01553.21 KRZ98776.1 - 0.0035 17.0 0.0 0.038 13.6 0.0 2.1 1 1 0 1 1 1 1 Acyltransferase Bt_P21 PF05560.11 KRZ98776.1 - 0.083 12.5 1.4 0.1 12.2 0.2 1.7 2 0 0 2 2 2 0 Bacillus thuringiensis P21 molecular chaperone protein RRM_1 PF00076.22 KRZ98777.1 - 2.3e-18 65.8 0.0 4.5e-18 64.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KRZ98777.1 - 0.0039 17.3 0.1 0.01 16.0 0.1 1.7 1 1 0 1 1 1 1 RNA recognition motif BOP1NT PF08145.12 KRZ98778.1 - 1.4e-107 359.4 9.4 2.6e-107 358.6 9.4 1.5 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 KRZ98778.1 - 6.1e-24 83.8 9.3 6.4e-10 39.5 0.2 6.6 6 1 1 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KRZ98778.1 - 7.1e-09 35.9 0.6 0.0025 18.1 0.0 5.2 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KRZ98778.1 - 0.021 13.8 0.0 0.042 12.8 0.0 1.4 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein RPA43_OB PF17875.1 KRZ98778.1 - 1.5 9.5 7.1 0.47 11.1 0.1 2.8 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I NUDIX PF00293.28 KRZ98779.1 - 1.7e-12 47.5 0.1 2.1e-12 47.2 0.1 1.2 1 0 0 1 1 1 1 NUDIX domain Chal_sti_synt_C PF02797.15 KRZ98779.1 - 0.033 14.2 0.1 0.06 13.3 0.1 1.5 1 1 0 1 1 1 0 Chalcone and stilbene synthases, C-terminal domain Porin_3 PF01459.22 KRZ98780.1 - 8.8e-73 245.1 1.2 9.9e-73 244.9 1.2 1.0 1 0 0 1 1 1 1 Eukaryotic porin Cyclin_N PF00134.23 KRZ98781.1 - 1e-10 41.4 0.5 2.9e-10 40.0 0.5 1.8 1 0 0 1 1 1 1 Cyclin, N-terminal domain HORMA PF02301.18 KRZ98782.1 - 3e-20 72.7 0.2 3.5e-20 72.5 0.2 1.1 1 0 0 1 1 1 1 HORMA domain ATG101 PF07855.12 KRZ98782.1 - 0.0067 16.4 0.5 0.02 14.9 0.5 1.7 1 1 0 1 1 1 1 Autophagy-related protein 101 Med21 PF11221.8 KRZ98782.1 - 0.059 13.6 0.0 0.076 13.3 0.0 1.2 1 0 0 1 1 1 0 Subunit 21 of Mediator complex bacHORMA_2 PF18173.1 KRZ98782.1 - 0.074 12.9 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 Bacterial HORMA domain 2 PPTA PF01239.22 KRZ98783.1 - 1.5e-30 104.0 13.6 2.6e-08 33.3 0.1 4.5 4 0 0 4 4 4 4 Protein prenyltransferase alpha subunit repeat M16C_assoc PF08367.11 KRZ98784.1 - 1.1e-73 247.5 0.7 1.6e-73 246.9 0.7 1.3 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 KRZ98784.1 - 3.7e-15 56.4 0.9 7e-12 45.7 0.2 2.8 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KRZ98784.1 - 4e-06 26.9 0.1 4e-06 26.9 0.1 2.7 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) Mito_carr PF00153.27 KRZ98785.1 - 1.6e-57 191.4 2.6 4.6e-19 68.1 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein zf-MYND PF01753.18 KRZ98786.1 - 7.5e-07 29.1 18.8 1.6e-06 28.1 18.8 1.6 1 0 0 1 1 1 1 MYND finger Peptidase_C50 PF03568.17 KRZ98787.1 - 3.1e-123 411.8 1.9 7.4e-123 410.6 0.0 2.2 2 0 0 2 2 2 1 Peptidase family C50 MMR_HSR1_Xtn PF16897.5 KRZ98787.1 - 2.4 8.2 6.1 0.82 9.7 1.1 2.8 2 0 0 2 2 2 0 C-terminal region of MMR_HSR1 domain Cupin_2 PF07883.11 KRZ98788.1 - 1.2e-21 76.2 0.5 3.9e-16 58.5 0.2 2.3 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.19 KRZ98788.1 - 0.00024 21.0 0.3 0.00091 19.1 0.2 2.0 1 1 1 2 2 2 1 AraC-like ligand binding domain YcxB PF14317.6 KRZ98788.1 - 0.0062 16.2 2.8 3 7.6 0.1 3.1 2 1 0 2 2 2 2 YcxB-like protein Cupin_1 PF00190.22 KRZ98788.1 - 0.034 13.8 0.0 1.3 8.6 0.0 2.2 2 0 0 2 2 2 0 Cupin MFS_1 PF07690.16 KRZ98789.1 - 5.5e-18 65.0 45.4 1.1e-15 57.4 45.4 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily Na_H_Exchanger PF00999.21 KRZ98791.1 - 2.8e-05 23.1 10.9 3.5e-05 22.8 10.9 1.2 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family Imm45 PF15572.6 KRZ98791.1 - 0.12 12.8 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 45 MFS_1 PF07690.16 KRZ98792.1 - 0.0005 19.1 4.2 0.00056 18.9 4.2 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Antimicrobial24 PF16049.5 KRZ98792.1 - 0.2 11.7 0.5 0.42 10.6 0.5 1.7 1 1 0 1 1 1 0 Frog antimicrobial peptide Glyco_hydro_3_C PF01915.22 KRZ98793.1 - 2e-11 44.3 0.1 2.2e-11 44.1 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Keratin PF02422.16 KRZ98793.1 - 0.039 13.6 0.1 0.043 13.5 0.1 1.1 1 0 0 1 1 1 0 Keratin NTP_transferase PF00483.23 KRZ98794.1 - 9.7e-54 182.6 0.0 1.4e-53 182.1 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 KRZ98794.1 - 5.6e-11 43.0 0.0 7.8e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.24 KRZ98794.1 - 1.3e-10 40.6 7.2 1.4e-08 34.1 1.2 3.9 3 0 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KRZ98794.1 - 3.3e-05 23.6 0.9 0.31 10.8 0.1 3.1 4 0 0 4 4 4 2 Hexapeptide repeat of succinyl-transferase CTP_transf_3 PF02348.19 KRZ98794.1 - 0.092 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Cytidylyltransferase Chalcone_2 PF16035.5 KRZ98795.1 - 1.4e-64 217.6 0.0 1.9e-64 217.2 0.0 1.2 1 0 0 1 1 1 1 Chalcone isomerase like Chalcone_3 PF16036.5 KRZ98795.1 - 9.2e-06 25.9 0.0 0.00088 19.4 0.1 2.2 2 0 0 2 2 2 2 Chalcone isomerase-like GSCFA PF08885.11 KRZ98795.1 - 0.098 12.3 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 GSCFA family Indigoidine_A PF04227.12 KRZ98796.1 - 1.6e-118 395.3 0.1 2.2e-118 394.9 0.1 1.2 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.24 KRZ98796.1 - 1.6e-08 34.2 0.0 1.9e-05 24.2 0.0 2.7 2 0 0 2 2 2 2 pfkB family carbohydrate kinase Skp1_POZ PF03931.15 KRZ98796.1 - 0.0097 16.1 1.0 0.93 9.7 0.0 3.1 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain Tti2 PF10521.9 KRZ98797.1 - 8.3e-64 215.8 5.4 1.3e-63 215.2 5.4 1.3 1 0 0 1 1 1 1 Tti2 family ArAE_1_C PF11728.8 KRZ98797.1 - 0.0041 17.1 0.6 0.01 15.8 0.6 1.7 1 0 0 1 1 1 1 Putative aromatic acid exporter C-terminal domain zf-Tim10_DDP PF02953.15 KRZ98798.1 - 4.6e-21 74.2 3.2 6e-21 73.9 3.2 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF3531 PF12049.8 KRZ98798.1 - 0.048 13.6 0.0 0.05 13.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3531) SPATA19 PF15212.6 KRZ98799.1 - 0.064 13.5 1.7 3.7 7.8 0.1 3.0 3 0 0 3 3 3 0 Spermatogenesis-associated protein 19, mitochondrial DUF4806 PF16064.5 KRZ98799.1 - 0.16 12.3 0.2 0.16 12.3 0.2 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4806) CK_II_beta PF01214.18 KRZ98799.1 - 0.52 10.1 1.9 2.6 7.8 1.9 2.0 1 1 0 1 1 1 0 Casein kinase II regulatory subunit LUC7 PF03194.15 KRZ98799.1 - 0.82 9.3 8.6 0.18 11.4 1.4 2.3 3 0 0 3 3 3 0 LUC7 N_terminus CREPT PF16566.5 KRZ98799.1 - 0.92 9.7 10.0 0.15 12.2 1.6 3.2 1 1 1 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour TBCA PF02970.16 KRZ98799.1 - 1.5 9.2 8.8 5.5 7.4 1.4 3.1 3 1 1 4 4 4 0 Tubulin binding cofactor A XhlA PF10779.9 KRZ98799.1 - 4.6 7.5 8.2 0.45 10.8 0.7 3.0 3 0 0 3 3 3 0 Haemolysin XhlA Aldedh PF00171.22 KRZ98800.1 - 1.7e-177 590.6 0.0 1.9e-177 590.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family GAIN PF16489.5 KRZ98800.1 - 0.0058 16.1 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 GPCR-Autoproteolysis INducing (GAIN) domain LuxC PF05893.14 KRZ98800.1 - 0.0074 15.4 0.0 0.014 14.4 0.0 1.5 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) adh_short_C2 PF13561.6 KRZ98801.1 - 3.8e-43 147.7 0.0 4.7e-43 147.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KRZ98801.1 - 2.6e-34 118.4 0.0 3.1e-34 118.2 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KRZ98801.1 - 6.5e-10 39.2 0.1 2.4e-09 37.4 0.0 1.6 1 1 0 2 2 2 1 KR domain Dak1_2 PF13684.6 KRZ98801.1 - 0.1 11.6 0.5 0.17 10.9 0.1 1.5 2 0 0 2 2 2 0 Dihydroxyacetone kinase family Glyco_transf_4 PF13439.6 KRZ98801.1 - 0.19 11.7 0.0 5.1 7.1 0.0 2.1 2 0 0 2 2 2 0 Glycosyltransferase Family 4 FA_hydroxylase PF04116.13 KRZ98802.1 - 1.1e-14 54.9 21.0 3.8e-14 53.2 17.6 2.1 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily MFS_1 PF07690.16 KRZ98803.1 - 7.8e-18 64.5 17.0 7.8e-18 64.5 17.0 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily PIG-Y PF15159.6 KRZ98803.1 - 0.082 13.8 2.8 0.73 10.8 0.3 3.2 3 0 0 3 3 3 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y DUF3671 PF12420.8 KRZ98803.1 - 0.51 10.4 5.2 0.39 10.8 0.3 2.6 2 1 1 3 3 3 0 Protein of unknown function DUF3899 PF13038.6 KRZ98803.1 - 7.9 7.1 9.4 2.1 8.9 0.8 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF3899) AAA_6 PF12774.7 KRZ98804.1 - 5.7e-113 377.2 5.1 1.5e-112 375.8 0.0 4.5 6 0 0 6 6 6 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KRZ98804.1 - 1.1e-99 334.3 11.9 1.1e-99 334.3 11.9 5.2 4 1 0 4 4 3 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 KRZ98804.1 - 7e-64 215.0 0.6 7e-64 215.0 0.6 3.5 4 0 0 4 4 2 1 ATP-binding dynein motor region AAA_8 PF12780.7 KRZ98804.1 - 5.6e-47 160.2 1.2 3.1e-46 157.8 0.1 2.9 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 KRZ98804.1 - 1.2e-44 152.0 0.3 9.9e-38 129.4 0.0 5.0 4 0 0 4 4 4 2 P-loop containing dynein motor region DHC_N1 PF08385.12 KRZ98804.1 - 7.5e-35 120.6 23.7 7.5e-35 120.6 23.7 4.1 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 1 MT PF12777.7 KRZ98804.1 - 5.4e-31 107.9 5.6 1e-30 107.0 5.6 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 KRZ98804.1 - 5.9e-25 87.9 0.0 1.3e-08 34.9 0.0 6.6 5 1 0 5 5 4 3 AAA domain (dynein-related subfamily) Dynein_heavy PF03028.15 KRZ98804.1 - 1.7e-18 66.8 0.0 1.7e-18 66.8 0.0 3.2 3 0 0 3 3 2 1 Dynein heavy chain region D6 P-loop domain AAA PF00004.29 KRZ98804.1 - 8.4e-15 55.4 0.0 7.6e-05 23.2 0.0 5.8 6 0 0 6 6 4 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KRZ98804.1 - 1.5e-10 41.5 1.8 0.0098 16.2 0.0 7.8 7 1 0 7 7 5 1 AAA domain AAA_lid_11 PF18198.1 KRZ98804.1 - 3.3e-10 40.0 0.2 1.5e-09 37.9 0.2 2.1 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_AAA_lid PF17852.1 KRZ98804.1 - 6.4e-10 39.2 0.1 3.1e-09 37.0 0.1 2.3 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_18 PF13238.6 KRZ98804.1 - 5.2e-07 30.3 0.1 1.2 9.7 0.0 5.2 4 0 0 4 4 4 2 AAA domain T2SSE PF00437.20 KRZ98804.1 - 1.6e-06 27.4 0.0 0.042 12.9 0.0 3.4 3 0 0 3 3 3 2 Type II/IV secretion system protein AAA_16 PF13191.6 KRZ98804.1 - 4.9e-06 27.0 0.0 2.8 8.3 0.0 5.2 4 1 0 5 5 4 1 AAA ATPase domain AAA_lid_1 PF17857.1 KRZ98804.1 - 6.1e-05 23.2 0.2 0.00045 20.4 0.1 2.7 2 0 0 2 2 1 1 AAA+ lid domain AAA_29 PF13555.6 KRZ98804.1 - 0.00013 21.6 0.1 5.5 6.8 0.0 3.7 3 0 0 3 3 3 0 P-loop containing region of AAA domain AAA_33 PF13671.6 KRZ98804.1 - 0.00028 21.1 0.1 2.4 8.3 0.0 4.6 4 0 0 4 4 4 1 AAA domain BRE1 PF08647.11 KRZ98804.1 - 0.001 19.1 3.1 0.001 19.1 3.1 4.3 4 1 0 4 4 2 1 BRE1 E3 ubiquitin ligase AAA_30 PF13604.6 KRZ98804.1 - 0.0026 17.5 0.3 21 4.8 0.0 4.1 4 1 0 4 4 4 0 AAA domain Mg_chelatase PF01078.21 KRZ98804.1 - 0.0036 16.7 0.9 0.8 9.0 0.0 3.6 4 0 0 4 4 4 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 KRZ98804.1 - 0.0037 17.6 1.0 1.5 9.1 0.0 4.4 5 1 0 5 5 4 1 AAA domain AAA_24 PF13479.6 KRZ98804.1 - 0.0054 16.5 0.0 5.3 6.7 0.0 3.6 3 0 0 3 3 3 0 AAA domain IstB_IS21 PF01695.17 KRZ98804.1 - 0.027 14.2 0.4 1.6 8.4 0.0 3.9 4 0 0 4 4 4 0 IstB-like ATP binding protein DUF948 PF06103.11 KRZ98804.1 - 0.039 14.2 1.1 0.45 10.8 0.1 3.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) AAA_25 PF13481.6 KRZ98804.1 - 0.04 13.5 0.0 0.3 10.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 KRZ98804.1 - 0.041 13.2 0.0 14 5.0 0.0 3.7 4 0 0 4 4 4 0 FtsK/SpoIIIE family RuvB_N PF05496.12 KRZ98804.1 - 0.061 13.1 0.5 3.2 7.5 0.0 3.4 3 0 0 3 3 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_11 PF13086.6 KRZ98804.1 - 0.076 12.8 0.0 0.076 12.8 0.0 4.1 3 1 0 3 3 2 0 AAA domain Exonuc_VII_L PF02601.15 KRZ98804.1 - 0.19 11.3 4.1 0.38 10.3 0.2 2.9 2 0 0 2 2 2 0 Exonuclease VII, large subunit CLZ PF16526.5 KRZ98804.1 - 0.43 11.0 6.0 1.6 9.2 0.9 4.0 3 0 0 3 3 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ABC_tran PF00005.27 KRZ98804.1 - 0.46 11.0 8.4 23 5.5 0.0 5.2 5 0 0 5 5 4 0 ABC transporter AAA_28 PF13521.6 KRZ98804.1 - 7.4 6.8 5.1 92 3.2 0.0 3.9 4 0 0 4 4 3 0 AAA domain ABC_trans_N PF14510.6 KRZ98805.1 - 1e-20 74.1 0.1 1e-20 74.1 0.1 1.9 2 0 0 2 2 2 1 ABC-transporter N-terminal rve PF00665.26 KRZ98806.1 - 2.2e-11 44.0 0.0 4e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain zf-CCHC PF00098.23 KRZ98806.1 - 0.064 13.4 0.8 0.14 12.3 0.8 1.6 1 0 0 1 1 1 0 Zinc knuckle DUF5098 PF17023.5 KRZ98807.1 - 0.0082 15.2 0.1 0.0086 15.1 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF5098) Taxilin PF09728.9 KRZ98807.1 - 0.021 14.0 0.3 0.024 13.8 0.3 1.0 1 0 0 1 1 1 0 Myosin-like coiled-coil protein Col_cuticle_N PF01484.17 KRZ98807.1 - 0.58 10.3 1.5 12 6.1 0.2 2.2 1 1 1 2 2 2 0 Nematode cuticle collagen N-terminal domain ATP-sulfurylase PF01747.17 KRZ98808.1 - 5.1e-82 274.4 0.0 7.7e-82 273.9 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.6 KRZ98808.1 - 1.8e-49 167.5 0.0 2.8e-49 166.8 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain CTP_transf_like PF01467.26 KRZ98808.1 - 0.032 14.4 0.0 0.08 13.1 0.0 1.7 1 0 0 1 1 1 0 Cytidylyltransferase-like 6PGD PF00393.19 KRZ98809.1 - 2.3e-127 424.3 0.0 2.9e-127 424.0 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KRZ98809.1 - 2.3e-51 174.1 0.0 3.3e-51 173.6 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KRZ98809.1 - 0.00045 20.7 0.1 0.00092 19.7 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_11 PF14833.6 KRZ98809.1 - 0.066 13.4 0.0 0.21 11.9 0.0 1.8 2 0 0 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase ANT PF03374.14 KRZ98809.1 - 0.095 13.0 0.0 2.4 8.5 0.0 2.4 2 0 0 2 2 2 0 Phage antirepressor protein KilAC domain p450 PF00067.22 KRZ98810.1 - 1.8e-49 168.8 0.0 2.4e-49 168.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SinI PF08671.10 KRZ98810.1 - 0.19 11.6 0.7 0.51 10.2 0.1 2.0 2 0 0 2 2 2 0 Anti-repressor SinI NOC3p PF07540.11 KRZ98811.1 - 4.3e-28 97.6 0.6 4.3e-28 97.6 0.6 3.0 3 1 0 3 3 3 1 Nucleolar complex-associated protein CBF PF03914.17 KRZ98811.1 - 5.2e-21 75.4 0.0 5.2e-21 75.4 0.0 2.8 3 0 0 3 3 3 1 CBF/Mak21 family SPRY PF00622.28 KRZ98812.1 - 5.2e-12 46.0 0.1 1.3e-11 44.6 0.1 1.8 1 0 0 1 1 1 1 SPRY domain AntA PF08346.12 KRZ98812.1 - 0.038 14.5 0.0 0.13 12.8 0.0 1.9 1 0 0 1 1 1 0 AntA/AntB antirepressor PH_4 PF15404.6 KRZ98813.1 - 2.7e-75 252.2 0.3 1.3e-73 246.7 0.0 2.9 3 0 0 3 3 3 1 Pleckstrin homology domain Spo7_2_N PF15407.6 KRZ98813.1 - 2e-21 75.4 0.1 7.6e-21 73.5 0.1 2.1 1 0 0 1 1 1 1 Sporulation protein family 7 PH PF00169.29 KRZ98813.1 - 8e-08 32.8 2.5 0.0027 18.2 0.0 4.9 4 1 0 4 4 4 2 PH domain PH_6 PF15406.6 KRZ98813.1 - 0.013 15.8 0.7 13 6.1 0.0 3.8 4 0 0 4 4 4 0 Pleckstrin homology domain PH_13 PF16652.5 KRZ98813.1 - 0.052 13.4 0.0 2.1 8.1 0.0 2.5 2 0 0 2 2 2 0 Pleckstrin homology domain DUF2689 PF10894.8 KRZ98814.1 - 0.11 12.3 0.0 0.3 10.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2689) zf-RING_2 PF13639.6 KRZ98814.1 - 0.18 12.2 0.8 0.58 10.5 0.8 1.9 1 0 0 1 1 1 0 Ring finger domain E1_dh PF00676.20 KRZ98815.1 - 1.2e-120 402.0 0.2 1.5e-120 401.7 0.2 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 KRZ98815.1 - 0.06 12.5 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase Msg2_C PF12373.8 KRZ98815.1 - 0.83 9.1 2.6 2 7.9 0.4 2.7 2 1 1 3 3 3 0 Major surface glycoprotein 2 C terminal KRTAP7 PF15034.6 KRZ98815.1 - 0.9 10.5 9.8 1.8 9.5 0.5 3.5 2 2 1 3 3 3 0 KRTAP type 7 family Sec63 PF02889.16 KRZ98816.1 - 6.9e-157 520.2 7.4 7.6e-85 284.2 0.3 2.9 3 0 0 3 3 3 2 Sec63 Brl domain DEAD PF00270.29 KRZ98816.1 - 1.2e-44 152.2 0.2 3.4e-26 92.1 0.0 3.1 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.15 KRZ98816.1 - 3.3e-30 105.3 1.3 1.3e-17 64.4 0.0 3.6 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit Helicase_PWI PF18149.1 KRZ98816.1 - 3.5e-24 85.1 7.3 1.1e-23 83.6 3.5 3.2 2 0 0 2 2 2 1 N-terminal helicase PWI domain Helicase_C PF00271.31 KRZ98816.1 - 9.8e-14 51.6 3.9 6.3e-09 36.2 0.0 5.4 3 2 0 3 3 3 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 KRZ98816.1 - 1.2e-07 32.1 0.1 0.0013 19.0 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KRZ98816.1 - 4e-06 26.7 0.0 0.0068 16.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 KRZ98816.1 - 0.01 15.6 0.0 1.7 8.4 0.0 3.1 2 0 0 2 2 2 0 IstB-like ATP binding protein PhoH PF02562.16 KRZ98816.1 - 0.012 15.1 0.0 1.2 8.5 0.0 2.9 3 0 0 3 3 3 0 PhoH-like protein T2SSE PF00437.20 KRZ98816.1 - 0.031 13.3 0.0 1.9 7.5 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein SRP19 PF01922.17 KRZ98817.1 - 5.1e-29 101.1 0.0 1e-28 100.1 0.0 1.5 1 0 0 1 1 1 1 SRP19 protein Pribosyltran PF00156.27 KRZ98818.1 - 2.7e-18 66.0 0.1 3.8e-18 65.5 0.1 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain SipA PF09052.10 KRZ98818.1 - 0.034 13.7 0.0 0.058 13.0 0.0 1.3 1 0 0 1 1 1 0 SipA N-terminal domain RRN9 PF10680.9 KRZ98819.1 - 0.00055 20.2 16.5 0.17 12.2 8.2 3.6 3 2 0 3 3 3 1 RNA polymerase I specific transcription initiation factor Cyt-b5 PF00173.28 KRZ98820.1 - 3e-21 75.3 1.0 3.3e-20 72.0 0.1 2.5 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 KRZ98820.1 - 8.9e-13 48.7 16.3 8.9e-13 48.7 16.3 1.8 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily COX14 PF14880.6 KRZ98820.1 - 0.88 9.5 4.7 4.4 7.2 0.1 2.5 2 0 0 2 2 2 0 Cytochrome oxidase c assembly Zds_C PF08632.10 KRZ98821.1 - 9.6e-31 105.3 2.4 3e-30 103.7 2.4 1.9 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term SieB PF14163.6 KRZ98821.1 - 0.081 12.4 0.8 0.2 11.1 0.8 1.6 1 0 0 1 1 1 0 Super-infection exclusion protein B Aconitase PF00330.20 KRZ98822.1 - 3e-115 385.9 0.1 2.9e-114 382.6 0.1 2.1 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KRZ98822.1 - 5.9e-31 107.5 0.0 1.4e-30 106.3 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.13 KRZ98822.1 - 0.0074 15.0 0.1 0.017 13.9 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF521) THOC2_N PF16134.5 KRZ98823.1 - 1.8e-179 598.4 16.5 1.8e-179 598.4 16.5 2.6 3 0 0 3 3 3 1 THO complex subunit 2 N-terminus Tho2 PF11262.8 KRZ98823.1 - 3.3e-80 269.5 10.5 3.3e-80 269.5 10.5 4.2 4 0 0 4 4 4 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.8 KRZ98823.1 - 5.9e-26 90.3 0.1 5.9e-26 90.3 0.1 2.9 3 0 0 3 3 3 1 Transcription- and export-related complex subunit zf-C2H2 PF00096.26 KRZ98824.1 - 1.5e-29 100.8 58.4 0.0014 18.9 0.7 9.4 9 0 0 9 9 9 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KRZ98824.1 - 4.6e-21 73.7 55.2 0.0028 18.4 0.2 9.4 9 0 0 9 9 9 8 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KRZ98824.1 - 2.3e-11 43.6 63.6 1.4e-05 25.3 1.1 9.4 9 1 1 10 10 9 6 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KRZ98824.1 - 0.0098 16.2 38.7 0.16 12.3 0.2 8.4 9 0 0 9 9 9 4 Zinc-finger double-stranded RNA-binding zf_C2H2_ZHX PF18387.1 KRZ98824.1 - 0.043 13.4 0.5 0.043 13.4 0.5 4.4 2 1 2 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-MIZ PF02891.20 KRZ98824.1 - 0.14 11.9 7.5 0.54 10.1 1.6 3.4 3 0 0 3 3 3 0 MIZ/SP-RING zinc finger zf_ZIC PF18366.1 KRZ98824.1 - 0.53 10.4 0.1 0.53 10.4 0.1 3.8 4 1 1 5 5 5 0 Zic proteins zinc finger domain zf-C2H2_8 PF15909.5 KRZ98824.1 - 1.4 9.3 26.8 0.32 11.3 4.0 4.2 2 1 3 5 5 5 0 C2H2-type zinc ribbon zinc_ribbon_4 PF13717.6 KRZ98824.1 - 1.4 8.9 11.4 0.59 10.1 0.2 4.1 4 0 0 4 4 4 0 zinc-ribbon domain zf-met PF12874.7 KRZ98824.1 - 2 8.9 37.2 0.91 10.0 0.1 7.9 9 0 0 9 9 8 0 Zinc-finger of C2H2 type zf-LITAF-like PF10601.9 KRZ98824.1 - 4.6 7.6 10.9 3.8 7.8 5.7 2.7 2 1 0 2 2 2 0 LITAF-like zinc ribbon domain Zn-ribbon_8 PF09723.10 KRZ98824.1 - 5.6 7.2 16.7 8.3 6.6 1.1 4.6 4 1 1 5 5 5 0 Zinc ribbon domain hDGE_amylase PF14701.6 KRZ98825.1 - 6.2e-176 585.8 0.1 9.1e-176 585.3 0.1 1.3 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 KRZ98825.1 - 2.7e-127 424.9 0.1 6.1e-127 423.7 0.0 1.6 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 KRZ98825.1 - 4.2e-77 259.2 0.0 8.1e-77 258.3 0.0 1.5 1 0 0 1 1 1 1 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 KRZ98825.1 - 1.5e-25 89.2 0.4 3.2e-25 88.1 0.4 1.6 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.24 KRZ98825.1 - 3e-07 30.3 0.8 4.4e-06 26.5 0.4 2.3 2 0 0 2 2 2 1 Alpha amylase, catalytic domain Aldedh PF00171.22 KRZ98826.1 - 2.7e-134 448.2 0.2 3.1e-134 448.0 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family RRF PF01765.19 KRZ98826.1 - 0.064 13.2 0.5 0.2 11.6 0.5 1.9 1 1 0 1 1 1 0 Ribosome recycling factor CdiA_C PF18451.1 KRZ98826.1 - 0.51 10.6 2.7 2.7 8.3 0.1 2.8 3 0 0 3 3 3 0 Contact-dependent growth inhibition CdiA C-terminal domain Pro_Al_protease PF02983.14 KRZ98826.1 - 0.64 10.1 4.0 1.1 9.3 0.0 3.0 3 0 0 3 3 3 0 Alpha-lytic protease prodomain SYF2 PF08231.12 KRZ98827.1 - 8.5e-32 110.8 24.8 8.5e-32 110.8 24.8 2.1 2 0 0 2 2 2 1 SYF2 splicing factor Methyltransf_3 PF01596.17 KRZ98828.1 - 4.6e-19 68.4 0.0 5.9e-19 68.1 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 KRZ98828.1 - 1.4e-12 48.6 0.0 2.2e-12 47.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CmcI PF04989.12 KRZ98828.1 - 0.01 15.6 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 0 Cephalosporin hydroxylase Methyltransf_31 PF13847.6 KRZ98828.1 - 0.03 14.1 0.0 0.04 13.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain CCD PF07860.11 KRZ98828.1 - 0.036 14.1 0.0 0.054 13.5 0.0 1.2 1 0 0 1 1 1 0 WisP family C-Terminal Region Syntaxin-18_N PF10496.9 KRZ98829.1 - 2.8e-15 56.3 0.4 2.8e-15 56.3 0.4 2.5 3 0 0 3 3 3 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.19 KRZ98829.1 - 0.0013 18.6 0.2 0.0024 17.8 0.2 1.5 1 0 0 1 1 1 1 SNARE domain Zea_mays_MuDR PF05928.11 KRZ98829.1 - 0.02 14.5 0.0 0.039 13.6 0.0 1.5 1 0 0 1 1 1 0 Zea mays MURB-like protein (MuDR) GTP_EFTU PF00009.27 KRZ98830.1 - 7.8e-44 149.6 0.1 1.6e-43 148.5 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.10 KRZ98830.1 - 1.7e-13 50.7 8.7 4.3e-13 49.4 8.7 1.7 1 0 0 1 1 1 1 HBS1 N-terminus GTP_EFTU_D3 PF03143.17 KRZ98830.1 - 7.6e-10 39.1 0.2 3.8e-09 36.8 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 KRZ98830.1 - 1.6e-05 24.9 0.1 0.00027 21.0 0.1 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 KRZ98830.1 - 0.016 15.4 0.2 1.3 9.3 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU_D2 PF03144.25 KRZ98830.1 - 0.062 13.7 0.4 0.2 12.0 0.1 2.0 2 0 0 2 2 2 0 Elongation factor Tu domain 2 DUF4769 PF15992.5 KRZ98830.1 - 0.79 9.5 2.9 2.2 8.0 2.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4769) Amidase PF01425.21 KRZ98831.1 - 1.5e-93 314.2 0.0 2.1e-93 313.8 0.0 1.2 1 0 0 1 1 1 1 Amidase Mannosyl_trans3 PF11051.8 KRZ98832.1 - 2.5e-82 276.3 0.3 4.9e-82 275.4 0.3 1.5 1 0 0 1 1 1 1 Mannosyltransferase putative Peptidase_U57 PF05582.12 KRZ98832.1 - 7.6 5.7 8.0 0.42 9.8 2.6 1.6 2 0 0 2 2 2 0 YabG peptidase U57 Topoisom_bac PF01131.20 KRZ98834.1 - 0.046 12.7 0.9 0.082 11.9 0.9 1.3 1 0 0 1 1 1 0 DNA topoisomerase Pyr_redox_2 PF07992.14 KRZ98836.1 - 8.6e-20 71.1 0.0 1.3e-19 70.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KRZ98836.1 - 1.1e-07 32.3 0.1 1.5e-06 28.6 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KRZ98836.1 - 0.00059 19.2 0.0 0.00096 18.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KRZ98836.1 - 0.009 16.0 0.5 0.061 13.3 0.0 2.4 3 0 0 3 3 3 1 FAD-NAD(P)-binding DUF1773 PF08593.10 KRZ98837.1 - 7e-09 36.6 0.0 2.2e-08 35.0 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function TAF PF02969.17 KRZ98837.1 - 0.031 14.4 0.0 0.08 13.1 0.0 1.6 2 0 0 2 2 2 0 TATA box binding protein associated factor (TAF) DUF5109 PF17134.4 KRZ98837.1 - 0.055 13.4 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5109) DUF4452 PF14618.6 KRZ98838.1 - 0.0011 18.8 2.8 0.0011 18.8 2.8 3.0 1 1 2 3 3 3 2 Domain of unknown function (DUF4452) tRNA-synt_1g PF09334.11 KRZ98838.1 - 0.22 10.2 0.1 0.37 9.5 0.1 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (M) LCE6A PF15858.5 KRZ98838.1 - 2.4 9.0 6.1 0.95 10.3 0.6 2.1 2 0 0 2 2 2 0 Late cornified envelope protein 6A family Cu_amine_oxid PF01179.20 KRZ98839.1 - 1.7e-158 527.9 0.1 2e-158 527.6 0.1 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 KRZ98839.1 - 0.0072 16.5 0.0 0.016 15.4 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain SRP1_TIP1 PF00660.17 KRZ98840.1 - 9.7e-21 73.7 0.1 1.5e-20 73.1 0.1 1.3 1 0 0 1 1 1 1 Seripauperin and TIP1 family Macoilin PF09726.9 KRZ98840.1 - 0.86 8.1 4.3 0.78 8.2 4.3 1.1 1 0 0 1 1 1 0 Macoilin family CDK2AP PF09806.9 KRZ98840.1 - 1.6 8.7 6.2 2.4 8.2 6.2 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Apt1 PF10351.9 KRZ98840.1 - 2.1 7.1 5.3 2.2 7.0 5.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain RAP1 PF07218.11 KRZ98840.1 - 5.4 5.2 15.1 5.5 5.1 15.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) BPS1 PF05633.11 KRZ98840.1 - 8.9 5.2 8.6 12 4.8 8.6 1.2 1 0 0 1 1 1 0 Protein BYPASS1-related Pkinase PF00069.25 KRZ98841.1 - 9.4e-39 133.4 4.8 1.3e-38 132.9 0.8 2.8 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KRZ98841.1 - 8.2e-21 74.4 0.0 2.4e-20 72.9 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase SWC7 PF17330.2 KRZ98842.1 - 0.0049 16.9 0.0 0.0092 16.0 0.0 1.5 1 0 0 1 1 1 1 SWR1 chromatin-remodelling complex, sub-unit Swc7 GAS PF13851.6 KRZ98842.1 - 0.018 14.4 0.1 0.041 13.2 0.2 1.6 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding ABC_membrane_2 PF06472.15 KRZ98843.1 - 2.2e-64 217.5 0.0 2.9e-64 217.1 0.0 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 KRZ98843.1 - 9.9e-19 68.2 0.0 1.9e-18 67.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KRZ98843.1 - 0.0018 18.2 0.0 0.0047 16.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KRZ98843.1 - 0.0037 17.8 1.3 0.019 15.5 0.0 2.7 3 1 0 3 3 3 1 AAA domain AAA_29 PF13555.6 KRZ98843.1 - 0.0042 16.8 0.1 0.011 15.5 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain NACHT PF05729.12 KRZ98843.1 - 0.032 14.2 0.0 0.061 13.2 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_7 PF12775.7 KRZ98843.1 - 0.046 13.2 0.0 0.079 12.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region SMC_N PF02463.19 KRZ98843.1 - 0.077 12.4 0.1 0.16 11.4 0.1 1.5 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain IstB_IS21 PF01695.17 KRZ98843.1 - 0.11 12.2 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 KRZ98843.1 - 0.18 11.2 0.0 0.31 10.4 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI FtsK_SpoIIIE PF01580.18 KRZ98843.1 - 0.18 11.1 0.0 0.33 10.3 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF2464 PF10240.9 KRZ98844.1 - 0.012 15.2 1.3 0.015 14.9 1.3 1.2 1 0 0 1 1 1 0 Multivesicular body subunit 12 DUF5435 PF17503.2 KRZ98844.1 - 0.014 15.2 0.2 0.017 14.8 0.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5435) GA PF01468.17 KRZ98844.1 - 0.051 13.9 0.3 0.13 12.5 0.3 1.7 1 0 0 1 1 1 0 GA module Pept_tRNA_hydro PF01195.19 KRZ98845.1 - 6.1e-39 133.7 0.0 8.1e-39 133.3 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase ATG101 PF07855.12 KRZ98846.1 - 4.6e-19 68.9 0.4 6.7e-19 68.4 0.4 1.3 1 0 0 1 1 1 1 Autophagy-related protein 101 EutQ PF06249.12 KRZ98846.1 - 0.03 14.1 1.3 0.056 13.2 1.3 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ CNOT1_HEAT PF16418.5 KRZ98846.1 - 0.11 12.6 0.7 0.56 10.3 0.3 2.0 2 0 0 2 2 2 0 CCR4-NOT transcription complex subunit 1 HEAT repeat CoA_binding_2 PF13380.6 KRZ98847.1 - 8.4e-30 103.6 0.0 9.6e-30 103.5 0.0 1.0 1 0 0 1 1 1 1 CoA binding domain Aconitase_2_N PF06434.13 KRZ98847.1 - 0.028 14.0 0.1 0.04 13.5 0.1 1.2 1 0 0 1 1 1 0 Aconitate hydratase 2 N-terminus Zn_clus PF00172.18 KRZ98848.1 - 5.5e-05 23.2 9.8 0.0001 22.3 9.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KRZ98848.1 - 0.00017 20.7 0.1 0.00045 19.3 0.1 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_transf_7N PF13733.6 KRZ98848.1 - 0.057 13.1 0.7 8.6 6.0 0.3 2.7 2 0 0 2 2 2 0 N-terminal region of glycosyl transferase group 7 BAR PF03114.18 KRZ98849.1 - 2.6e-14 53.4 2.4 4.6e-14 52.7 2.4 1.3 1 0 0 1 1 1 1 BAR domain SH3_2 PF07653.17 KRZ98849.1 - 5.5e-12 45.2 0.0 1.5e-11 43.8 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KRZ98849.1 - 4.7e-11 42.1 0.1 4.7e-11 42.1 0.1 2.3 3 0 0 3 3 3 1 SH3 domain SH3_9 PF14604.6 KRZ98849.1 - 8.8e-09 35.1 0.0 2.1e-08 33.9 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain IL28A PF15177.6 KRZ98849.1 - 0.043 13.7 0.8 0.14 12.0 0.1 2.0 2 0 0 2 2 2 0 Interleukin-28A Euplotes_phero PF05842.11 KRZ98849.1 - 0.41 11.2 2.1 17 5.9 0.1 2.9 3 0 0 3 3 3 0 Euplotes octocarinatus mating pheromone protein LRR_8 PF13855.6 KRZ98850.1 - 8.4e-07 28.7 4.6 4.7e-06 26.3 4.2 2.3 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KRZ98850.1 - 0.00088 19.6 3.6 0.00088 19.6 3.6 3.6 1 1 2 3 3 3 2 Leucine Rich repeats (2 copies) WD40 PF00400.32 KRZ98851.1 - 0.015 16.1 0.4 2.6 9.1 0.1 3.5 3 0 0 3 3 3 0 WD domain, G-beta repeat LisH PF08513.11 KRZ98851.1 - 0.019 14.9 0.0 0.046 13.7 0.0 1.6 1 0 0 1 1 1 0 LisH Mito_carr PF00153.27 KRZ98852.1 - 8.5e-54 179.5 0.5 3.9e-19 68.4 0.1 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein Ribosom_S12_S23 PF00164.25 KRZ98853.1 - 6.2e-51 170.8 0.2 8.1e-51 170.4 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Med26 PF08711.11 KRZ98854.1 - 1.3e-07 31.5 0.0 3.7e-07 30.1 0.0 1.8 1 0 0 1 1 1 1 TFIIS helical bundle-like domain FAD_SOX PF18371.1 KRZ98854.1 - 0.014 15.7 0.1 0.043 14.2 0.1 1.8 1 0 0 1 1 1 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase LSM14 PF12701.7 KRZ98855.1 - 5.9e-28 96.8 0.0 9.3e-28 96.2 0.0 1.3 1 0 0 1 1 1 1 Scd6-like Sm domain SM-ATX PF14438.6 KRZ98855.1 - 6.6e-06 26.2 0.0 1.4e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Ataxin 2 SM domain TFIIA PF03153.13 KRZ98855.1 - 8.9e-05 22.7 15.6 9.9e-05 22.5 15.6 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit FDF PF09532.10 KRZ98855.1 - 0.00072 20.4 0.7 0.00072 20.4 0.7 3.9 2 2 1 3 3 3 2 FDF domain K_trans PF02705.16 KRZ98856.1 - 2.3e-106 356.4 2.9 2.9e-106 356.1 2.9 1.1 1 0 0 1 1 1 1 K+ potassium transporter K_trans PF02705.16 KRZ98857.1 - 8.3e-25 87.3 0.4 9.6e-25 87.1 0.4 1.0 1 0 0 1 1 1 1 K+ potassium transporter FMO-like PF00743.19 KRZ98858.1 - 1.5e-40 139.1 0.5 3e-25 88.6 0.2 2.7 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KRZ98858.1 - 1.1e-20 74.1 4.2 1.1e-16 60.9 0.3 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KRZ98858.1 - 3.7e-17 62.5 0.0 1.5e-16 60.5 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KRZ98858.1 - 7.6e-11 42.2 0.0 3.5e-08 33.6 0.0 3.2 3 1 0 3 3 3 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 KRZ98858.1 - 4.4e-08 32.7 2.7 1.6e-06 27.5 0.8 3.3 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KRZ98858.1 - 9.1e-08 32.1 0.0 0.018 14.6 0.0 3.2 1 1 1 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KRZ98858.1 - 1e-06 28.9 0.0 4e-06 27.0 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KRZ98858.1 - 8.2e-06 26.3 0.4 0.24 12.0 0.0 3.5 4 0 0 4 4 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KRZ98858.1 - 2.2e-05 23.9 0.0 0.018 14.3 0.0 2.3 2 0 0 2 2 2 2 Thi4 family HI0933_like PF03486.14 KRZ98858.1 - 0.00018 20.3 0.0 0.0028 16.4 0.0 2.5 3 0 0 3 3 3 1 HI0933-like protein FAD_oxidored PF12831.7 KRZ98858.1 - 0.028 13.8 0.0 0.12 11.7 0.0 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KRZ98858.1 - 0.044 12.8 0.0 0.07 12.2 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Amino_oxidase PF01593.24 KRZ98858.1 - 0.1 11.9 0.0 10 5.3 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.19 KRZ98858.1 - 0.17 11.1 0.5 0.6 9.3 0.4 1.8 2 0 0 2 2 2 0 FAD binding domain FAD_binding_2 PF00890.24 KRZ98858.1 - 0.24 10.5 0.9 13 4.7 2.1 2.2 2 0 0 2 2 2 0 FAD binding domain Mcl1_mid PF12341.8 KRZ98859.1 - 3.2e-83 279.5 0.0 8.7e-81 271.5 0.0 2.9 3 0 0 3 3 3 1 Minichromosome loss protein, Mcl1, middle region ANAPC4_WD40 PF12894.7 KRZ98859.1 - 8e-10 38.9 0.2 0.0017 18.7 0.0 5.0 2 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 KRZ98859.1 - 0.0013 18.8 0.1 0.53 10.4 0.0 4.0 3 1 2 5 5 5 1 Ciliary BBSome complex subunit 2, middle region RAB3GAP2_N PF14655.6 KRZ98859.1 - 0.002 17.5 0.0 0.0044 16.3 0.0 1.5 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF4513 PF14983.6 KRZ98859.1 - 0.01 15.9 0.0 0.024 14.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4513) PRP1_N PF06424.12 KRZ98859.1 - 5.1 7.5 13.2 0.084 13.3 5.0 2.1 3 0 0 3 3 3 0 PRP1 splicing factor, N-terminal Sugar_tr PF00083.24 KRZ98861.1 - 6.1e-105 351.7 16.7 7.6e-105 351.4 16.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KRZ98861.1 - 2.1e-35 122.3 36.8 8.6e-31 107.1 17.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KRZ98861.1 - 2e-10 39.8 23.8 5.6e-08 31.8 6.9 3.1 3 0 0 3 3 3 2 MFS/sugar transport protein OATP PF03137.20 KRZ98861.1 - 0.0012 17.2 4.1 0.0012 17.2 4.1 1.9 2 1 1 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family TB2_DP1_HVA22 PF03134.19 KRZ98861.1 - 0.0018 18.1 0.8 0.0018 18.1 0.8 2.7 3 0 0 3 3 3 1 TB2/DP1, HVA22 family MFS_1_like PF12832.7 KRZ98861.1 - 0.0091 14.9 0.1 0.0091 14.9 0.1 2.6 2 1 0 2 2 2 1 MFS_1 like family TRI12 PF06609.13 KRZ98861.1 - 0.021 13.3 11.1 0.39 9.1 4.2 2.2 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) ELO PF01151.18 KRZ98862.1 - 7.2e-71 238.6 15.5 8.7e-71 238.4 15.5 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family KH_1 PF00013.29 KRZ98863.1 - 5.3e-13 48.6 8.4 1.3e-06 28.1 0.1 5.1 5 0 0 5 5 5 4 KH domain WD40 PF00400.32 KRZ98864.1 - 6.6e-18 64.7 14.9 0.003 18.4 0.1 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat DUF3258 PF11646.8 KRZ98864.1 - 0.15 12.2 0.1 0.31 11.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF3258 Choline_kinase PF01633.20 KRZ98865.1 - 2.8e-33 115.3 2.7 4e-33 114.8 2.7 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 KRZ98865.1 - 2.7e-06 27.5 0.0 0.00082 19.4 0.0 2.1 2 0 0 2 2 2 2 Phosphotransferase enzyme family Choline_kin_N PF04428.14 KRZ98866.1 - 3.4e-15 55.5 0.1 4.7e-15 55.0 0.1 1.2 1 0 0 1 1 1 1 Choline kinase N terminus Choline_kinase PF01633.20 KRZ98866.1 - 1.8e-09 37.5 0.0 4e-09 36.4 0.0 1.6 2 0 0 2 2 2 1 Choline/ethanolamine kinase SSP160 PF06933.11 KRZ98866.1 - 0.042 12.1 4.3 0.051 11.8 4.3 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Rootletin PF15035.6 KRZ98867.1 - 9.8e-05 22.4 11.6 9.8e-05 22.4 11.6 6.1 3 1 1 4 4 4 1 Ciliary rootlet component, centrosome cohesion DUF4201 PF13870.6 KRZ98867.1 - 0.00058 19.6 19.4 0.00058 19.6 19.4 6.6 3 2 1 5 5 5 2 Domain of unknown function (DUF4201) Fez1 PF06818.15 KRZ98867.1 - 0.0021 18.5 16.4 0.0021 18.5 16.4 6.1 2 1 4 6 6 6 1 Fez1 DHR10 PF18595.1 KRZ98867.1 - 0.011 15.7 2.8 0.011 15.7 2.8 8.8 5 3 3 9 9 9 0 Designed helical repeat protein 10 domain Tup_N PF08581.10 KRZ98867.1 - 0.014 15.7 6.8 0.014 15.7 6.8 8.8 8 2 3 11 11 11 0 Tup N-terminal NPV_P10 PF05531.12 KRZ98867.1 - 0.039 14.4 0.6 0.039 14.4 0.6 8.1 6 1 2 9 9 9 0 Nucleopolyhedrovirus P10 protein FlaC_arch PF05377.11 KRZ98867.1 - 0.072 13.5 0.3 0.072 13.5 0.3 9.5 9 3 1 10 10 10 0 Flagella accessory protein C (FlaC) Ycf70 PF17382.2 KRZ98867.1 - 9.6 6.7 8.2 0.72 10.3 0.5 3.2 2 1 0 2 2 2 0 Uncharacterized Ycf70-like Glyco_hydro_88 PF07470.13 KRZ98868.1 - 6.4e-85 285.3 0.9 7.4e-85 285.0 0.9 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 MFS_1 PF07690.16 KRZ98869.1 - 6.4e-31 107.6 26.4 1.3e-30 106.5 26.1 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Glyco_hydro_3_C PF01915.22 KRZ98870.1 - 6.2e-45 153.7 0.0 1e-44 152.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KRZ98870.1 - 7e-35 120.9 0.0 1.3e-34 120.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KRZ98870.1 - 9e-22 77.0 0.1 2.2e-21 75.7 0.1 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain GPR_Gpa2_C PF11970.8 KRZ98871.1 - 2.5e-28 98.0 1.2 3.9e-28 97.3 1.2 1.3 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term PHTB1_N PF14727.6 KRZ98871.1 - 0.072 12.4 0.1 0.11 11.8 0.1 1.2 1 0 0 1 1 1 0 PTHB1 N-terminus Alpha-amylase PF00128.24 KRZ98872.1 - 1e-115 386.9 0.3 1.9e-115 386.1 0.3 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 KRZ98872.1 - 2.4e-05 24.4 0.0 5.5e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain hDGE_amylase PF14701.6 KRZ98872.1 - 0.0055 15.8 0.0 0.0093 15.1 0.0 1.3 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain DUF3459 PF11941.8 KRZ98872.1 - 0.067 13.5 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3459) Sugar_tr PF00083.24 KRZ98873.1 - 1.6e-29 103.0 14.4 1.8e-29 102.9 14.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KRZ98873.1 - 1.5e-06 27.4 7.5 1.8e-06 27.2 7.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 KRZ98873.1 - 0.35 9.4 11.0 0.014 13.9 5.3 1.5 2 0 0 2 2 2 0 MFS/sugar transport protein CAP PF00188.26 KRZ98874.1 - 9.4e-19 68.5 0.7 1.9e-18 67.5 0.7 1.5 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Asp PF00026.23 KRZ98874.1 - 2.2e-10 40.5 0.7 3.2e-10 39.9 0.7 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KRZ98874.1 - 2e-05 24.9 0.2 6.2e-05 23.3 0.0 1.8 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KRZ98874.1 - 0.11 13.2 0.1 0.18 12.5 0.1 1.4 1 0 0 1 1 1 0 Aspartyl protease Arrestin_N PF00339.29 KRZ98875.1 - 2.8e-07 30.7 0.0 5.1e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Sec8_exocyst PF04048.14 KRZ98875.1 - 0.11 12.4 0.1 0.2 11.6 0.1 1.4 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain M20_dimer PF07687.14 KRZ98876.1 - 8.7e-09 35.3 0.1 2.2e-08 34.0 0.1 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 KRZ98876.1 - 1.5e-08 34.6 0.1 2.6e-08 33.8 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 LRR_8 PF13855.6 KRZ98877.1 - 3.5e-06 26.7 54.3 3.9e-06 26.5 12.7 6.2 7 1 0 7 7 7 4 Leucine rich repeat LRR_4 PF12799.7 KRZ98877.1 - 5.7e-06 26.6 65.7 0.0013 19.0 12.8 6.8 5 2 2 7 7 7 5 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KRZ98877.1 - 0.00027 20.7 49.0 0.0031 17.5 2.6 9.4 10 0 0 10 10 10 4 Leucine Rich repeat LRR_9 PF14580.6 KRZ98877.1 - 0.0094 15.5 13.9 0.18 11.3 9.1 3.4 3 0 0 3 3 3 1 Leucine-rich repeat LRR_1 PF00560.33 KRZ98877.1 - 0.034 14.6 45.6 0.72 10.6 1.2 9.2 8 1 0 8 8 8 0 Leucine Rich Repeat MFS_1 PF07690.16 KRZ98878.1 - 0.00019 20.5 0.6 0.00022 20.3 0.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily FDX-ACB PF03147.14 KRZ98878.1 - 0.035 14.5 0.1 0.051 14.0 0.1 1.3 1 0 0 1 1 1 0 Ferredoxin-fold anticodon binding domain Rad60-SLD PF11976.8 KRZ98879.1 - 7.9e-18 64.1 2.3 2.2e-17 62.6 2.3 1.8 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ndc1_Nup PF09531.10 KRZ98879.1 - 1.1 7.9 4.0 1.6 7.3 4.0 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup VAR1 PF05316.12 KRZ98880.1 - 0.00049 19.3 2.6 0.00086 18.5 2.6 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein (VAR1) AnfG_VnfG PF03139.15 KRZ98880.1 - 0.12 12.5 0.1 0.26 11.4 0.1 1.5 1 0 0 1 1 1 0 Vanadium/alternative nitrogenase delta subunit ThiF PF00899.21 KRZ98881.1 - 1e-58 198.6 0.0 1.6e-58 198.0 0.0 1.2 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 KRZ98881.1 - 3e-15 56.7 0.2 1.4e-14 54.5 0.1 2.2 3 0 0 3 3 3 1 Rhodanese-like domain Shikimate_DH PF01488.20 KRZ98881.1 - 0.00096 19.2 0.0 0.0033 17.5 0.0 1.9 1 1 1 2 2 2 1 Shikimate / quinate 5-dehydrogenase TSC22 PF01166.18 KRZ98881.1 - 0.015 15.6 0.3 0.046 14.0 0.3 1.8 1 0 0 1 1 1 0 TSC-22/dip/bun family UDPG_MGDP_dh_N PF03721.14 KRZ98881.1 - 0.15 11.6 0.2 0.29 10.7 0.2 1.6 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_7 PF13241.6 KRZ98881.1 - 0.16 12.4 0.0 0.35 11.3 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding JIP_LZII PF16471.5 KRZ98881.1 - 0.16 12.1 0.8 0.35 11.1 0.8 1.4 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II EMP24_GP25L PF01105.24 KRZ98882.1 - 1e-56 191.8 2.4 1.2e-56 191.6 2.4 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD CarboxypepD_reg PF13620.6 KRZ98882.1 - 0.13 12.5 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain ydhR PF08803.11 KRZ98883.1 - 3.7e-39 132.5 0.0 4.1e-39 132.4 0.0 1.0 1 0 0 1 1 1 1 Putative mono-oxygenase ydhR NUMOD1 PF07453.13 KRZ98883.1 - 0.055 13.8 0.1 0.16 12.2 0.0 1.8 2 0 0 2 2 2 0 NUMOD1 domain NUC153 PF08159.12 KRZ98884.1 - 5e-16 58.2 9.4 1.8e-15 56.4 1.9 3.1 3 0 0 3 3 3 2 NUC153 domain Profilin PF00235.19 KRZ98885.1 - 7.7e-47 158.7 0.1 8.5e-47 158.6 0.1 1.0 1 0 0 1 1 1 1 Profilin DUF2894 PF11445.8 KRZ98887.1 - 0.044 14.3 0.2 0.046 14.2 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2894) SopE_GEF PF07487.13 KRZ98887.1 - 0.071 13.2 0.0 0.076 13.1 0.0 1.1 1 0 0 1 1 1 0 SopE GEF domain Pox_A_type_inc PF04508.12 KRZ98887.1 - 0.19 11.6 0.3 0.45 10.4 0.0 1.7 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat DUF1129 PF06570.11 KRZ98887.1 - 0.27 10.7 0.4 0.32 10.4 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) LPD30 PF18850.1 KRZ98887.1 - 0.27 11.0 1.2 0.36 10.6 1.2 1.2 1 0 0 1 1 1 0 Large polyvalent protein associated domain 30 YCII PF03795.14 KRZ98888.1 - 0.00075 19.9 0.0 0.00099 19.5 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain ABC_trans_N PF14510.6 KRZ98889.1 - 4.9e-21 75.1 0.0 8.3e-21 74.4 0.0 1.4 1 0 0 1 1 1 1 ABC-transporter N-terminal adh_short_C2 PF13561.6 KRZ98890.1 - 9.1e-42 143.2 0.0 1.2e-41 142.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KRZ98890.1 - 2.8e-36 124.8 0.4 3.4e-36 124.5 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KRZ98890.1 - 4.6e-10 39.7 0.2 6.5e-10 39.2 0.2 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KRZ98890.1 - 0.011 15.2 0.1 0.015 14.7 0.1 1.1 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Peptidase_C14 PF00656.22 KRZ98891.1 - 3.8e-68 230.1 0.2 4.8e-68 229.8 0.2 1.1 1 0 0 1 1 1 1 Caspase domain TFIIA PF03153.13 KRZ98891.1 - 7.7 6.4 15.0 13 5.6 15.0 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3336 PF11815.8 KRZ98893.1 - 1.4e-34 118.8 3.3 2.5e-34 118.0 3.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 KRZ98893.1 - 2.4e-06 27.9 0.0 6.7e-06 26.4 0.0 1.8 2 0 0 2 2 2 1 Patatin-like phospholipase MHCassoc_trimer PF08831.10 KRZ98893.1 - 0.044 13.8 0.4 0.13 12.3 0.4 1.8 1 0 0 1 1 1 0 Class II MHC-associated invariant chain trimerisation domain ELP6 PF09807.9 KRZ98894.1 - 2.6e-06 27.1 0.0 7.4e-06 25.6 0.0 1.7 1 1 0 1 1 1 1 Elongation complex protein 6 ATPase PF06745.13 KRZ98894.1 - 0.00092 18.6 0.0 0.0013 18.1 0.0 1.2 1 0 0 1 1 1 1 KaiC Mito_carr PF00153.27 KRZ98895.1 - 3.7e-60 199.9 2.6 3.3e-22 78.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4952 PF16310.5 KRZ98895.1 - 0.0039 17.4 0.0 0.0087 16.3 0.0 1.5 1 0 0 1 1 1 1 Domian of unknown function (DUF4952) Serine_protease PF18405.1 KRZ98895.1 - 0.0076 15.4 1.8 0.095 11.8 0.4 2.4 2 1 0 2 2 2 1 Gammaproteobacterial serine protease Peptidase_M22 PF00814.25 KRZ98896.1 - 1.2e-52 179.3 0.0 2.4e-52 178.3 0.0 1.5 1 1 0 1 1 1 1 Glycoprotease family DUF4882 PF16223.5 KRZ98896.1 - 0.011 14.9 0.5 0.016 14.4 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4882) Nse4_C PF08743.10 KRZ98897.1 - 5.2e-28 97.1 0.3 1.6e-27 95.6 0.3 1.9 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 KRZ98897.1 - 4.8e-08 33.0 3.8 1.5e-07 31.4 3.8 1.9 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE SR-25 PF10500.9 KRZ98897.1 - 1.8 8.1 11.5 0.28 10.8 6.0 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Secretin_N_2 PF07655.13 KRZ98897.1 - 2.9 8.5 14.5 0.27 11.8 8.0 2.4 2 0 0 2 2 2 0 Secretin N-terminal domain Mlh1_C PF16413.5 KRZ98898.1 - 8e-78 261.5 4.1 1.5e-77 260.6 4.1 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 KRZ98898.1 - 3.5e-33 113.8 0.2 6.7e-33 112.9 0.2 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 KRZ98898.1 - 1.6e-12 47.4 0.6 3.2e-12 46.4 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KRZ98898.1 - 3.8e-06 27.4 0.0 9.9e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase polyprenyl_synt PF00348.17 KRZ98899.1 - 4.5e-08 32.5 0.0 6.3e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase Ribosomal_L3 PF00297.22 KRZ98900.1 - 4.8e-18 65.3 2.7 9.5e-17 61.0 1.9 2.3 1 1 1 2 2 2 2 Ribosomal protein L3 Ribosomal_L6 PF00347.23 KRZ98901.1 - 1.4e-19 70.5 6.2 2.9e-10 40.7 3.5 2.2 2 0 0 2 2 2 2 Ribosomal protein L6 Ribosomal_S4 PF00163.19 KRZ98902.1 - 8.6e-14 52.2 1.4 1.3e-13 51.6 1.4 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.25 KRZ98902.1 - 6.9e-12 44.9 0.0 1.5e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 S4 domain Pox_A_type_inc PF04508.12 KRZ98902.1 - 0.13 12.1 0.0 0.86 9.6 0.0 2.3 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat SKG6 PF08693.10 KRZ98903.1 - 3.6e-06 26.3 0.6 5.8e-06 25.6 0.0 1.6 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Orf78 PF06024.12 KRZ98903.1 - 0.15 12.3 0.1 1.8 8.9 0.0 2.9 2 0 0 2 2 2 0 Orf78 (ac78) FAD_binding_8 PF08022.12 KRZ98904.1 - 4.1e-24 84.8 0.0 7.3e-24 84.0 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 KRZ98904.1 - 3.2e-23 82.2 10.0 3.2e-23 82.2 10.0 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KRZ98904.1 - 4.3e-16 59.4 0.0 7e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain MLANA PF14991.6 KRZ98904.1 - 0.0055 17.0 0.0 0.019 15.2 0.0 1.9 1 0 0 1 1 1 1 Protein melan-A Exonuc_VII_L PF02601.15 KRZ98905.1 - 3.2 7.2 8.1 4.6 6.7 8.1 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Orthopox_B11R PF07033.11 KRZ98905.1 - 7.3 6.5 8.1 6.5 6.6 0.6 2.7 1 1 1 2 2 2 0 Orthopoxvirus B11R protein Acetyltransf_1 PF00583.25 KRZ98906.1 - 6.9e-10 39.2 0.1 3.9e-09 36.8 0.1 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KRZ98906.1 - 5.7e-09 36.3 0.6 9.7e-09 35.5 0.2 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KRZ98906.1 - 2.5e-08 33.9 0.1 2.1e-06 27.7 0.1 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KRZ98906.1 - 0.056 13.6 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Sec16_C PF12931.7 KRZ98907.1 - 3.2e-67 227.3 0.0 6.3e-67 226.4 0.0 1.5 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 KRZ98907.1 - 2.1e-10 41.2 0.0 1.3e-09 38.7 0.0 2.4 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region Nup96 PF12110.8 KRZ98907.1 - 0.033 13.3 0.0 0.075 12.1 0.0 1.6 1 0 0 1 1 1 0 Nuclear protein 96 TPR_1 PF00515.28 KRZ98908.1 - 9.4e-27 91.7 28.6 2e-07 30.6 0.3 8.2 9 0 0 9 9 9 5 Tetratricopeptide repeat ANAPC8 PF04049.13 KRZ98908.1 - 4e-23 82.0 3.7 9.3e-22 77.6 3.7 2.8 1 1 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_8 PF13181.6 KRZ98908.1 - 2.6e-19 67.7 29.3 6e-07 29.2 0.6 9.9 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_2 PF07719.17 KRZ98908.1 - 3.5e-17 61.1 28.7 1.1e-05 25.1 0.1 9.1 11 0 0 11 11 9 4 Tetratricopeptide repeat TPR_14 PF13428.6 KRZ98908.1 - 1.1e-14 53.8 0.7 8.9e-05 23.0 0.0 6.6 5 2 2 7 7 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 KRZ98908.1 - 2e-14 53.0 5.4 1.2e-07 31.2 0.0 5.1 2 2 2 4 4 4 3 TPR repeat TPR_16 PF13432.6 KRZ98908.1 - 4.6e-13 49.6 0.9 2.6e-06 28.0 0.0 4.3 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KRZ98908.1 - 7.7e-11 42.3 4.5 0.28 11.7 0.0 6.6 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 KRZ98908.1 - 2.6e-09 36.4 0.8 0.0042 17.0 0.0 6.0 5 0 0 5 5 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KRZ98908.1 - 3e-09 37.0 23.1 0.09 13.0 5.6 6.2 5 1 0 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 KRZ98908.1 - 8.9e-09 35.5 11.9 0.0066 16.7 0.0 6.0 4 1 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 KRZ98908.1 - 5.6e-05 23.2 18.7 0.041 14.3 0.0 7.2 9 1 0 9 9 8 2 Tetratricopeptide repeat ChAPs PF09295.10 KRZ98908.1 - 0.00038 19.6 2.5 0.006 15.6 0.0 3.1 3 1 1 4 4 4 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_9 PF13371.6 KRZ98908.1 - 0.00059 19.9 0.0 1.2 9.3 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_15 PF13429.6 KRZ98908.1 - 0.0024 17.1 1.0 0.28 10.4 0.2 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 KRZ98908.1 - 0.003 18.1 16.5 3.5 8.5 0.0 7.7 9 0 0 9 9 7 1 Tetratricopeptide repeat DUF3856 PF12968.7 KRZ98908.1 - 0.01 15.9 0.1 0.14 12.3 0.0 2.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF3856) SHNi-TPR PF10516.9 KRZ98908.1 - 0.079 12.4 2.0 5.4 6.5 0.0 3.6 4 0 0 4 4 4 0 SHNi-TPR RPN7 PF10602.9 KRZ98908.1 - 0.3 10.8 10.1 9.5 5.9 0.1 4.5 4 1 1 5 5 5 0 26S proteasome subunit RPN7 Sel1 PF08238.12 KRZ98908.1 - 4.8 8.0 9.0 35 5.3 0.4 4.7 6 0 0 6 6 3 0 Sel1 repeat MPC PF03650.13 KRZ98910.1 - 7.1e-46 154.9 0.0 8.2e-46 154.7 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers UQ_con PF00179.26 KRZ98911.1 - 3.6e-16 59.1 0.2 6.1e-16 58.3 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KRZ98911.1 - 0.059 13.7 5.0 0.097 13.0 0.1 2.3 2 0 0 2 2 2 0 RWD domain ABC_membrane PF00664.23 KRZ98912.1 - 2.5e-71 240.5 37.3 6.6e-38 130.9 18.8 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KRZ98912.1 - 5.4e-50 169.5 0.7 3.9e-30 105.2 0.1 3.1 3 1 0 3 3 3 2 ABC transporter SMC_N PF02463.19 KRZ98912.1 - 7e-12 45.3 8.0 0.00034 20.1 2.6 4.2 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KRZ98912.1 - 1.4e-06 28.4 3.7 0.14 12.0 0.1 5.2 4 1 1 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 KRZ98912.1 - 4.5e-05 23.5 1.0 0.25 11.4 0.1 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 KRZ98912.1 - 0.00036 20.2 0.5 0.39 10.5 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KRZ98912.1 - 0.00038 20.4 0.1 0.21 11.5 0.1 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KRZ98912.1 - 0.00052 20.4 0.5 0.085 13.2 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 KRZ98912.1 - 0.0012 19.4 3.6 1.7 9.1 0.1 3.4 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.6 KRZ98912.1 - 0.0037 17.5 0.6 1.6 9.0 0.0 3.2 2 1 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 KRZ98912.1 - 0.0048 17.0 0.9 0.41 10.7 0.1 2.6 2 0 0 2 2 2 1 Dynamin family AAA_24 PF13479.6 KRZ98912.1 - 0.0058 16.4 0.1 0.79 9.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KRZ98912.1 - 0.0082 15.9 0.6 2.6 7.8 0.0 3.2 3 0 0 3 3 3 1 IstB-like ATP binding protein DUF87 PF01935.17 KRZ98912.1 - 0.016 15.3 0.3 0.49 10.4 0.0 2.7 2 0 0 2 2 2 0 Helicase HerA, central domain TsaE PF02367.17 KRZ98912.1 - 0.058 13.4 0.1 0.66 10.0 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_15 PF13175.6 KRZ98912.1 - 0.098 12.3 14.7 1.1 8.9 4.1 3.6 3 1 0 3 3 3 0 AAA ATPase domain Zeta_toxin PF06414.12 KRZ98912.1 - 0.1 11.9 0.1 5.6 6.2 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_30 PF13604.6 KRZ98912.1 - 0.1 12.3 0.3 6.3 6.5 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA PF00004.29 KRZ98912.1 - 0.11 13.0 3.0 26 5.2 0.1 3.9 3 2 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.18 KRZ98912.1 - 0.16 11.3 0.2 9.6 5.5 0.1 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family NACHT PF05729.12 KRZ98912.1 - 0.19 11.6 1.6 2.4 8.1 0.0 2.8 3 0 0 3 3 3 0 NACHT domain Roc PF08477.13 KRZ98912.1 - 0.2 11.9 0.7 40 4.5 0.0 3.1 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase DnaB_C PF03796.15 KRZ98912.1 - 1.3 8.3 5.6 7.6 5.8 0.4 3.4 4 0 0 4 4 4 0 DnaB-like helicase C terminal domain Aconitase PF00330.20 KRZ98913.1 - 1e-149 499.5 0.0 1.3e-149 499.1 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KRZ98913.1 - 2.2e-45 154.2 0.0 4.3e-45 153.3 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Zn_clus PF00172.18 KRZ98914.1 - 5.7e-09 36.0 6.4 1.1e-08 35.1 6.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TSC22 PF01166.18 KRZ98914.1 - 0.12 12.8 0.1 0.54 10.6 0.1 2.2 1 0 0 1 1 1 0 TSC-22/dip/bun family Putative_PNPOx PF01243.20 KRZ98915.1 - 2.3e-12 46.9 0.0 1.2e-11 44.6 0.0 1.9 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.7 KRZ98915.1 - 0.00012 22.1 0.0 0.0099 15.9 0.0 2.1 2 0 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase ORC4_C PF14629.6 KRZ98916.1 - 9.1e-48 162.5 2.4 2.3e-47 161.2 2.4 1.7 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 KRZ98916.1 - 1.2e-11 45.3 0.0 3.1e-11 44.0 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 KRZ98916.1 - 5e-06 26.6 0.6 5e-06 26.6 0.6 2.4 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 KRZ98916.1 - 0.0005 20.3 1.3 0.0043 17.3 0.1 3.1 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 KRZ98916.1 - 0.0016 18.8 0.2 0.013 15.9 0.2 2.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 KRZ98916.1 - 0.003 17.0 0.1 0.72 9.2 0.0 2.6 2 0 0 2 2 2 2 Bacterial TniB protein AAA_7 PF12775.7 KRZ98916.1 - 0.013 15.0 0.0 0.04 13.4 0.0 1.8 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 KRZ98916.1 - 0.016 15.2 0.5 0.1 12.7 0.0 2.8 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KRZ98916.1 - 0.056 13.4 0.7 0.29 11.1 0.0 2.7 3 1 0 3 3 3 0 AAA domain (dynein-related subfamily) RGS PF00615.19 KRZ98917.1 - 3.7e-17 62.7 6.2 9.8e-09 35.5 0.4 3.0 3 0 0 3 3 3 2 Regulator of G protein signaling domain DEP PF00610.21 KRZ98917.1 - 5.1e-08 32.9 0.0 1.7e-07 31.2 0.0 1.9 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) eIF2_C PF09173.11 KRZ98918.1 - 2.9e-34 117.2 0.3 6.7e-34 116.0 0.3 1.7 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 KRZ98918.1 - 1e-22 80.6 0.3 8.3e-22 77.7 0.3 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KRZ98918.1 - 1.1e-11 45.0 1.7 1.6e-11 44.4 0.5 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KRZ98918.1 - 0.0028 17.7 0.0 0.0059 16.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KRZ98918.1 - 0.0051 16.7 0.1 0.049 13.5 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase ProQ_C PF17516.2 KRZ98918.1 - 0.038 13.4 0.1 0.089 12.2 0.1 1.6 1 0 0 1 1 1 0 ProQ C-terminal domain MMR_HSR1_Xtn PF16897.5 KRZ98918.1 - 0.088 12.8 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Dynamin_N PF00350.23 KRZ98918.1 - 0.15 12.1 0.7 1.1 9.2 0.0 2.6 2 1 0 2 2 2 0 Dynamin family Zn_clus PF00172.18 KRZ98919.1 - 2.4e-08 33.9 11.2 4.3e-08 33.2 11.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KRZ98920.1 - 8.2e-33 113.8 38.3 1.9e-26 92.9 22.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KRZ98920.1 - 3.1e-09 36.2 9.8 1.8e-08 33.7 9.9 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.7 KRZ98920.1 - 1.6e-07 30.5 19.8 0.00051 19.0 6.4 2.6 2 1 0 2 2 2 2 MFS_1 like family MFS_2 PF13347.6 KRZ98920.1 - 7.2e-07 28.1 24.4 0.024 13.2 6.4 3.1 2 1 0 3 3 3 3 MFS/sugar transport protein OATP PF03137.20 KRZ98920.1 - 2.9 6.1 17.4 0.65 8.2 5.0 2.7 3 1 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Bac_export_2 PF01312.19 KRZ98920.1 - 9.4 5.3 8.4 3.8 6.6 0.4 2.2 2 0 0 2 2 2 0 FlhB HrpN YscU SpaS Family AA_permease PF00324.21 KRZ98921.1 - 4.6e-128 427.8 39.1 5.6e-128 427.5 39.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KRZ98921.1 - 1.3e-39 136.3 42.6 1.5e-39 136.1 42.6 1.0 1 0 0 1 1 1 1 Amino acid permease Acetyltransf_7 PF13508.7 KRZ98922.1 - 6.7e-05 23.2 0.6 0.00033 21.0 0.6 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KRZ98922.1 - 0.00043 20.2 0.6 0.0019 18.1 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KRZ98922.1 - 0.0013 18.9 0.0 0.003 17.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 KRZ98922.1 - 0.0034 17.4 0.1 0.24 11.5 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Luciferase_N PF05295.11 KRZ98922.1 - 0.014 15.4 0.2 8.1 6.5 0.0 3.5 3 0 0 3 3 3 0 Luciferase/LBP N-terminal domain Acetyltransf_CG PF14542.6 KRZ98922.1 - 0.015 15.4 0.0 0.038 14.1 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_15 PF17013.5 KRZ98922.1 - 0.029 13.8 0.1 0.051 13.0 0.1 1.4 1 0 0 1 1 1 0 Putative acetyl-transferase HSA PF07529.13 KRZ98923.1 - 1e-11 44.9 0.8 1e-11 44.9 0.8 3.5 5 0 0 5 5 5 1 HSA Myb_DNA-bind_6 PF13921.6 KRZ98923.1 - 1.3e-08 34.9 0.7 5.6e-08 32.9 0.7 2.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KRZ98923.1 - 0.12 12.6 0.0 0.54 10.5 0.1 2.2 2 0 0 2 2 2 0 Myb-like DNA-binding domain ZapA PF05164.13 KRZ98923.1 - 0.75 10.3 3.6 3.9 8.0 3.6 2.3 1 1 0 1 1 1 0 Cell division protein ZapA NPCC PF08058.11 KRZ98924.1 - 0.00027 21.0 5.2 1.1 9.4 4.8 2.6 2 1 0 2 2 2 2 Nuclear pore complex component Anoctamin PF04547.12 KRZ98924.1 - 0.071 11.9 2.8 0.11 11.3 2.8 1.3 1 0 0 1 1 1 0 Calcium-activated chloride channel Herpes_LMP2 PF07415.11 KRZ98924.1 - 0.072 11.9 1.4 0.1 11.3 1.4 1.1 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein LapA_dom PF06305.11 KRZ98924.1 - 2.9 7.8 4.6 10 6.0 0.2 2.4 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF3377 PF11857.8 KRZ98924.1 - 3.7 7.5 6.6 7.8 6.5 6.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) DHHC PF01529.20 KRZ98924.1 - 8.4 6.5 6.4 15 5.7 6.4 1.3 1 0 0 1 1 1 0 DHHC palmitoyltransferase Sen15 PF09631.10 KRZ98925.1 - 9.3e-26 90.0 0.1 1.1e-25 89.9 0.1 1.0 1 0 0 1 1 1 1 Sen15 protein SUN PF03856.13 KRZ98926.1 - 2.6e-86 289.1 16.2 3.1e-86 288.8 16.2 1.0 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) Zn_clus PF00172.18 KRZ98927.1 - 1.9e-07 31.1 8.4 3.4e-07 30.3 8.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_S8 PF00410.19 KRZ98927.1 - 0.011 15.6 0.4 0.047 13.6 0.4 2.1 1 0 0 1 1 1 0 Ribosomal protein S8 UPF0506 PF11703.8 KRZ98927.1 - 0.43 11.0 3.2 0.85 10.0 3.2 1.4 1 0 0 1 1 1 0 UPF0506 Septin PF00735.18 KRZ98928.1 - 2e-113 378.3 0.1 3.7e-113 377.5 0.1 1.4 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KRZ98928.1 - 9.9e-07 28.8 0.0 2.4e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KRZ98928.1 - 0.00019 21.4 4.1 0.0047 16.8 0.1 3.4 3 1 0 3 3 3 1 RsgA GTPase GTP_EFTU PF00009.27 KRZ98928.1 - 0.0011 18.6 0.9 0.031 13.8 0.0 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 KRZ98928.1 - 0.0029 18.0 0.0 0.01 16.2 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain FtsK_SpoIIIE PF01580.18 KRZ98928.1 - 0.0031 16.9 0.0 0.0071 15.7 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family Roc PF08477.13 KRZ98928.1 - 0.0038 17.4 0.4 0.0094 16.2 0.0 1.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KRZ98928.1 - 0.013 15.1 0.1 0.051 13.2 0.1 2.0 1 1 0 1 1 1 0 Ras family DUF5082 PF16888.5 KRZ98928.1 - 0.013 15.7 1.3 0.03 14.6 1.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) AAA_7 PF12775.7 KRZ98928.1 - 0.018 14.5 0.0 0.033 13.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region KAP_NTPase PF07693.14 KRZ98928.1 - 0.02 14.2 0.0 0.04 13.1 0.0 1.8 1 1 0 1 1 1 0 KAP family P-loop domain AIG1 PF04548.16 KRZ98928.1 - 0.029 13.7 0.0 0.069 12.5 0.0 1.6 1 0 0 1 1 1 0 AIG1 family NB-ARC PF00931.22 KRZ98928.1 - 0.034 13.3 0.0 0.067 12.4 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_22 PF13401.6 KRZ98928.1 - 0.078 13.2 0.4 0.23 11.7 0.1 2.2 2 1 0 2 2 2 0 AAA domain XhlA PF10779.9 KRZ98928.1 - 0.13 12.5 1.8 0.31 11.3 1.8 1.7 1 0 0 1 1 1 0 Haemolysin XhlA Dynamin_N PF00350.23 KRZ98928.1 - 0.6 10.1 9.1 2.7 8.0 0.1 3.5 2 2 1 3 3 3 0 Dynamin family 14-3-3 PF00244.20 KRZ98929.1 - 8.7e-104 345.9 4.4 1e-103 345.6 4.4 1.0 1 0 0 1 1 1 1 14-3-3 protein FlaF PF07309.11 KRZ98929.1 - 0.00025 21.0 0.2 0.00058 19.9 0.2 1.6 1 0 0 1 1 1 1 Flagellar protein FlaF Peptidase_M24 PF00557.24 KRZ98930.1 - 0.00013 21.7 0.0 0.00022 21.0 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 MFS_1 PF07690.16 KRZ98931.1 - 2.7e-12 46.3 47.2 5.8e-07 28.8 34.7 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KRZ98931.1 - 7.9e-09 34.5 24.3 1e-08 34.1 24.3 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KRZ98932.1 - 3.2e-31 108.6 21.5 3.2e-31 108.6 21.5 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KRZ98932.1 - 9.9e-06 24.7 14.7 6.5e-05 22.0 13.2 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KRZ98932.1 - 1.4e-05 23.8 2.2 2.4e-05 23.0 2.2 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) FMO-like PF00743.19 KRZ98933.1 - 1.3e-26 93.1 2.1 1e-13 50.6 0.0 2.0 1 1 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KRZ98933.1 - 4.1e-11 42.6 0.7 1.1e-10 41.2 0.3 1.7 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KRZ98933.1 - 3e-10 39.9 4.1 4.3e-09 36.1 4.1 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KRZ98933.1 - 0.00042 19.6 0.1 0.001 18.4 0.1 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase PAS_3 PF08447.12 KRZ98933.1 - 0.046 14.0 0.1 0.13 12.5 0.1 1.7 1 0 0 1 1 1 0 PAS fold Shikimate_DH PF01488.20 KRZ98933.1 - 0.092 12.8 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase LktC PF06261.11 KRZ98933.1 - 0.14 12.1 0.6 0.3 11.0 0.1 1.8 2 0 0 2 2 2 0 Actinobacillus actinomycetemcomitans leukotoxin activator LktC Flocculin_t3 PF13928.6 KRZ98934.1 - 1.5e-24 86.2 67.7 6.1e-14 52.3 21.6 3.6 3 0 0 3 3 3 2 Flocculin type 3 repeat T2SSF PF00482.23 KRZ98935.1 - 0.23 11.4 0.0 0.43 10.5 0.0 1.4 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F Aminotran_1_2 PF00155.21 KRZ98936.1 - 7.9e-63 212.8 0.0 9.4e-63 212.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KRZ98936.1 - 0.017 13.6 0.0 0.032 12.8 0.0 1.4 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Ribosomal_S17 PF00366.20 KRZ98937.1 - 2.9e-20 72.1 1.1 2.9e-20 72.1 1.1 1.9 2 0 0 2 2 2 1 Ribosomal protein S17 IFN-gamma PF00714.17 KRZ98937.1 - 0.14 12.0 4.8 0.076 12.9 0.8 2.2 1 1 1 2 2 2 0 Interferon gamma MitMem_reg PF13012.6 KRZ98937.1 - 0.72 10.3 3.3 3.5 8.1 0.3 2.3 1 1 1 2 2 2 0 Maintenance of mitochondrial structure and function eIF3_N PF09440.10 KRZ98937.1 - 2 8.8 8.3 0.25 11.8 3.0 2.1 3 0 0 3 3 3 0 eIF3 subunit 6 N terminal domain Nucleoside_tran PF01733.18 KRZ98938.1 - 1.5e-55 188.7 10.7 1.5e-55 188.7 10.7 1.6 2 0 0 2 2 2 1 Nucleoside transporter TMEM37 PF15108.6 KRZ98938.1 - 2.9 7.7 14.9 0.17 11.7 5.7 3.0 2 2 1 3 3 3 0 Voltage-dependent calcium channel gamma-like subunit protein family Diphthamide_syn PF01866.17 KRZ98940.1 - 4e-69 233.4 0.1 6.2e-69 232.7 0.1 1.3 1 0 0 1 1 1 1 Putative diphthamide synthesis protein adh_short PF00106.25 KRZ98941.1 - 7.5e-21 74.5 0.1 1e-20 74.0 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KRZ98941.1 - 7.3e-15 55.2 0.0 9.4e-15 54.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KRZ98941.1 - 0.0002 21.3 0.0 0.00051 20.0 0.0 1.6 1 1 0 1 1 1 1 KR domain Gemini_AL1 PF00799.20 KRZ98941.1 - 0.09 13.1 0.7 0.17 12.2 0.7 1.5 1 0 0 1 1 1 0 Geminivirus Rep catalytic domain SPC25 PF06703.11 KRZ98942.1 - 1.6e-35 122.3 7.2 1.8e-35 122.1 7.2 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) Tetraspanin PF00335.20 KRZ98942.1 - 0.044 13.5 0.1 0.044 13.5 0.1 1.2 1 0 0 1 1 1 0 Tetraspanin family Pox_A9 PF04835.12 KRZ98942.1 - 0.074 13.2 0.6 0.12 12.5 0.2 1.5 2 0 0 2 2 2 0 A9 protein conserved region zf-C3HC4 PF00097.25 KRZ98943.1 - 1.8e-06 27.7 4.8 3.6e-06 26.7 4.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KRZ98943.1 - 2.1e-06 27.6 3.3 4.1e-06 26.6 3.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KRZ98943.1 - 8.9e-06 25.6 3.8 8.9e-06 25.6 3.8 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 KRZ98943.1 - 6.9e-05 23.1 6.3 0.00018 21.7 6.3 1.7 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KRZ98943.1 - 0.00033 20.4 4.2 0.0011 18.8 4.2 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KRZ98943.1 - 0.0009 19.0 4.5 0.0021 17.9 1.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KRZ98943.1 - 0.014 15.3 11.8 3.4 7.6 11.7 3.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KRZ98943.1 - 0.36 11.0 8.6 0.054 13.7 4.0 2.0 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING TFR_dimer PF04253.15 KRZ98944.1 - 4.4e-27 94.6 0.0 1e-26 93.4 0.0 1.7 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 KRZ98944.1 - 3.4e-08 33.4 0.1 1.1e-07 31.8 0.0 1.9 2 0 0 2 2 2 1 Peptidase family M28 Glycos_transf_4 PF00953.21 KRZ98944.1 - 0.0016 18.4 0.2 0.0033 17.4 0.2 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 4 PA PF02225.22 KRZ98944.1 - 0.011 15.7 0.0 0.034 14.2 0.0 1.8 2 0 0 2 2 2 0 PA domain MFS_1 PF07690.16 KRZ98945.1 - 3.9e-37 128.0 56.5 1.5e-36 126.1 54.5 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KRZ98945.1 - 8e-22 77.4 15.9 1.2e-21 76.8 15.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KRZ98945.1 - 5.8e-09 35.3 20.9 5.8e-09 35.3 20.9 3.2 1 1 1 3 3 3 1 Sugar (and other) transporter DUF2238 PF09997.9 KRZ98945.1 - 0.014 15.2 0.3 0.043 13.6 0.3 1.8 1 0 0 1 1 1 0 Predicted membrane protein (DUF2238) SecD_SecF PF02355.16 KRZ98945.1 - 0.15 11.5 3.7 5.5 6.3 0.2 3.0 2 0 0 2 2 2 0 Protein export membrane protein XK-related PF09815.9 KRZ98945.1 - 0.75 8.8 8.5 1.9 7.4 0.7 2.5 2 0 0 2 2 2 0 XK-related protein PHO4 PF01384.20 KRZ98946.1 - 4.3e-117 390.9 15.5 5e-117 390.7 15.5 1.0 1 0 0 1 1 1 1 Phosphate transporter family DUF4225 PF13988.6 KRZ98946.1 - 0.065 12.8 1.3 0.18 11.3 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4225) Hexapep_2 PF14602.6 KRZ98947.1 - 9.7e-14 50.8 5.2 3.2e-11 42.8 4.0 2.4 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.24 KRZ98947.1 - 7.1e-11 41.4 9.0 1.7e-09 37.0 5.1 2.7 3 0 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Mac PF12464.8 KRZ98947.1 - 0.0064 16.7 0.0 0.013 15.7 0.0 1.6 1 0 0 1 1 1 1 Maltose acetyltransferase Peptidase_M20 PF01546.28 KRZ98948.1 - 6.1e-24 84.9 0.0 7.2e-24 84.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KRZ98948.1 - 4.2e-05 23.4 0.0 7.8e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain ApoC-I PF04691.12 KRZ98949.1 - 0.18 11.8 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 Apolipoprotein C-I (ApoC-1) PALP PF00291.25 KRZ98950.1 - 1.7e-61 208.2 0.0 1.9e-61 208.0 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Fungal_trans PF04082.18 KRZ98951.1 - 8.6e-26 90.5 6.1 1.4e-25 89.8 6.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain SUV3_C PF12513.8 KRZ98951.1 - 0.1 12.5 0.4 0.31 11.0 0.1 2.0 2 0 0 2 2 2 0 Mitochondrial degradasome RNA helicase subunit C terminal MFS_1 PF07690.16 KRZ98952.1 - 1.1e-15 57.5 17.4 1.1e-15 57.5 17.4 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.16 KRZ98953.1 - 5.2e-15 55.2 11.7 5.2e-15 55.2 11.7 2.2 1 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KRZ98953.1 - 2.6e-07 29.9 4.5 8.2e-07 28.2 4.2 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter Cation_ATPase_C PF00689.21 KRZ98953.1 - 0.0067 16.2 8.4 0.42 10.3 0.0 3.4 2 2 1 3 3 3 2 Cation transporting ATPase, C-terminus NLRC4_HD2 PF17776.1 KRZ98953.1 - 0.036 14.6 0.0 0.076 13.5 0.0 1.5 1 0 0 1 1 1 0 NLRC4 helical domain HD2 YoqO PF14037.6 KRZ98953.1 - 0.47 11.0 3.4 1.7 9.2 0.1 2.7 3 0 0 3 3 3 0 YoqO-like protein MFS_1 PF07690.16 KRZ98954.1 - 5.3e-11 42.0 3.2 6.7e-11 41.7 3.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily FMO-like PF00743.19 KRZ98955.1 - 6.4e-21 74.4 0.3 1e-14 53.9 0.3 2.0 1 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KRZ98955.1 - 4.4e-11 42.6 0.3 1.4e-09 37.6 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KRZ98955.1 - 2.2e-09 36.9 0.0 6.3e-07 28.9 0.0 2.1 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KRZ98955.1 - 3.9e-08 32.9 0.0 1.3e-07 31.1 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KRZ98955.1 - 2e-07 31.1 0.0 2.7e-05 24.2 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KRZ98955.1 - 4.6e-05 23.6 0.0 0.00011 22.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KRZ98955.1 - 0.00094 18.9 0.0 0.066 12.8 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Glu_dehyd_C PF16912.5 KRZ98955.1 - 0.036 13.5 0.1 0.26 10.8 0.0 2.2 3 0 0 3 3 3 0 Glucose dehydrogenase C-terminus HI0933_like PF03486.14 KRZ98955.1 - 0.21 10.3 0.0 1.1 7.9 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein SET PF00856.28 KRZ98956.1 - 1.9e-21 77.2 0.0 2.4e-21 76.9 0.0 1.1 1 0 0 1 1 1 1 SET domain Dsl1_C PF11989.8 KRZ98956.1 - 0.018 14.8 0.8 0.19 11.4 0.1 2.2 2 0 0 2 2 2 0 Retrograde transport protein Dsl1 C terminal Topoisom_bac PF01131.20 KRZ98957.1 - 1.6e-108 363.4 0.0 1.9e-108 363.2 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 KRZ98957.1 - 6.4e-16 58.5 0.0 1.9e-15 57.0 0.0 1.8 1 0 0 1 1 1 1 Toprim domain zf-CCCH_4 PF18044.1 KRZ98958.1 - 1.1e-08 34.7 5.5 2.4e-08 33.6 5.5 1.6 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 KRZ98958.1 - 3e-07 30.2 2.8 8.2e-07 28.8 2.8 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KRZ98958.1 - 1.5e-06 28.0 9.8 3.2e-06 27.0 9.8 1.6 1 0 0 1 1 1 1 Zinc finger domain Torus PF16131.5 KRZ98958.1 - 0.0019 18.9 0.3 0.004 17.8 0.3 1.5 1 0 0 1 1 1 1 Torus domain zf-CCCH_2 PF14608.6 KRZ98958.1 - 0.034 14.6 8.4 0.063 13.8 8.4 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger RSN1_7TM PF02714.15 KRZ98959.1 - 5.2e-82 275.2 29.0 5.2e-82 275.2 29.0 2.0 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KRZ98959.1 - 9e-38 129.5 4.0 9e-38 129.5 4.0 2.7 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KRZ98959.1 - 8.9e-34 117.2 0.1 1.5e-33 116.5 0.1 1.4 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter FTA4 PF13093.6 KRZ98960.1 - 1.4e-44 152.4 21.5 2.8e-44 151.5 21.5 1.5 1 1 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 AGH PF17558.2 KRZ98960.1 - 0.31 11.2 0.1 0.31 11.2 0.1 2.4 2 0 0 2 2 2 0 Androgenic gland hormone GLTP PF08718.11 KRZ98960.1 - 6.4 7.0 7.0 0.89 9.8 1.5 2.2 2 1 0 2 2 2 0 Glycolipid transfer protein (GLTP) Ribosomal_60s PF00428.19 KRZ98961.1 - 2.1e-24 85.9 11.3 2.4e-24 85.7 11.3 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein Ribosomal_S19 PF00203.21 KRZ98962.1 - 4.9e-32 109.7 0.1 8.1e-32 108.9 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S19 Mito_carr PF00153.27 KRZ98963.1 - 1.6e-58 194.6 0.6 4e-22 77.9 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.19 KRZ98963.1 - 0.013 15.9 0.0 0.026 14.9 0.0 1.7 1 1 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family CHASE4 PF05228.13 KRZ98964.1 - 0.044 14.0 0.0 0.064 13.5 0.0 1.3 1 0 0 1 1 1 0 CHASE4 domain COX16 PF14138.6 KRZ98965.1 - 8.2 7.0 6.1 26 5.4 0.0 3.7 4 1 0 4 4 4 0 Cytochrome c oxidase assembly protein COX16 NAD_binding_4 PF07993.12 KRZ98966.1 - 1.3e-08 34.3 0.2 7.1e-08 31.9 0.0 1.9 2 0 0 2 2 2 1 Male sterility protein Epimerase PF01370.21 KRZ98966.1 - 0.00011 21.8 0.0 0.00013 21.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KRZ98966.1 - 0.00026 20.9 0.0 0.0024 17.8 0.0 2.2 2 1 0 2 2 2 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KRZ98966.1 - 0.0042 16.1 0.0 0.0072 15.4 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family HPP PF04982.13 KRZ98967.1 - 1.5e-36 125.2 6.3 1.5e-36 125.2 6.3 1.4 2 0 0 2 2 2 1 HPP family Acatn PF13000.7 KRZ98967.1 - 0.048 12.2 0.1 0.072 11.6 0.1 1.2 1 0 0 1 1 1 0 Acetyl-coenzyme A transporter 1 DUF3961 PF13106.6 KRZ98967.1 - 0.089 12.4 0.0 0.56 9.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3961) E1-E2_ATPase PF00122.20 KRZ98968.1 - 2.3e-49 167.4 0.1 2.3e-49 167.4 0.1 2.5 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KRZ98968.1 - 5.7e-45 153.3 1.1 5.7e-45 153.3 1.1 2.2 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KRZ98968.1 - 3.8e-20 73.1 1.2 3.4e-19 70.0 1.2 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KRZ98968.1 - 3e-15 56.1 0.0 1.2e-14 54.1 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KRZ98968.1 - 2.1e-12 46.5 0.0 5.8e-12 45.1 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KRZ98968.1 - 2.6e-06 27.4 2.2 7.2e-06 25.9 1.2 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3784 PF12650.7 KRZ98968.1 - 0.0094 16.1 10.0 0.048 13.9 0.0 3.3 4 0 0 4 4 4 2 Domain of unknown function (DUF3784) RseC_MucC PF04246.12 KRZ98968.1 - 0.06 13.3 0.0 0.2 11.6 0.0 1.9 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC Sua5_yciO_yrdC PF01300.18 KRZ98969.1 - 2.1e-52 177.2 0.0 3.1e-52 176.7 0.0 1.3 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 KRZ98969.1 - 2.2e-30 106.0 0.0 3.2e-30 105.4 0.0 1.2 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding DUF4451 PF14616.6 KRZ98970.1 - 2.6e-29 101.9 3.0 5.7e-29 100.8 3.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) zf-Di19 PF05605.12 KRZ98970.1 - 0.0012 19.1 8.3 0.29 11.4 3.4 3.0 2 1 1 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding DUF5531 PF17671.1 KRZ98970.1 - 0.15 11.9 1.6 0.32 10.9 0.1 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5531) Xpo1 PF08389.12 KRZ98971.1 - 0.003 17.6 15.1 0.023 14.8 0.2 5.3 3 3 0 3 3 3 2 Exportin 1-like protein IBN_N PF03810.19 KRZ98971.1 - 0.0081 16.0 3.0 0.11 12.5 0.2 3.6 3 0 0 3 3 3 1 Importin-beta N-terminal domain Fis1_TPR_C PF14853.6 KRZ98972.1 - 1.6e-24 85.7 2.4 2.3e-24 85.2 0.3 2.2 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 KRZ98972.1 - 7.1e-16 57.6 0.4 1.9e-15 56.2 0.4 1.8 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.17 KRZ98972.1 - 0.0073 16.3 0.8 0.019 15.1 0.3 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat A_deamin PF02137.18 KRZ98973.1 - 2.2e-32 112.8 0.0 2.6e-32 112.6 0.0 1.1 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain Erg28 PF03694.13 KRZ98973.1 - 0.15 12.5 0.0 0.34 11.3 0.0 1.5 1 0 0 1 1 1 0 Erg28 like protein Ank_2 PF12796.7 KRZ98974.1 - 1.1e-08 35.5 0.2 4.4e-08 33.6 0.0 1.9 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 KRZ98974.1 - 4.4e-08 33.2 0.0 0.008 16.6 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 KRZ98974.1 - 9.6e-08 32.2 0.1 5.1e-05 23.5 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KRZ98974.1 - 4.2e-07 29.8 0.4 0.021 15.3 0.0 3.3 3 1 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 KRZ98974.1 - 4.2e-05 24.0 0.0 0.00021 21.8 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ribul_P_3_epim PF00834.19 KRZ98975.1 - 1.3e-70 236.9 0.0 1.5e-70 236.6 0.0 1.1 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family ThiG PF05690.14 KRZ98975.1 - 0.00014 21.3 0.2 0.0002 20.8 0.2 1.2 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG OMPdecase PF00215.24 KRZ98975.1 - 0.011 15.4 0.1 0.023 14.3 0.0 1.6 2 0 0 2 2 2 0 Orotidine 5'-phosphate decarboxylase / HUMPS family QRPTase_C PF01729.19 KRZ98975.1 - 0.065 13.0 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain Alb1 PF09135.11 KRZ98976.1 - 9.9e-08 32.8 9.8 9.9e-08 32.8 9.8 1.9 1 1 1 2 2 2 1 Alb1 Imm43 PF15570.6 KRZ98976.1 - 0.025 14.6 2.0 0.036 14.1 2.0 1.2 1 0 0 1 1 1 0 Immunity protein 43 Mannosyl_trans3 PF11051.8 KRZ98978.1 - 6.8e-74 248.7 0.1 1.1e-73 248.0 0.1 1.4 1 0 0 1 1 1 1 Mannosyltransferase putative WW PF00397.26 KRZ98979.1 - 1.8e-11 43.9 0.4 2.9e-11 43.2 0.4 1.4 1 0 0 1 1 1 1 WW domain DUF3402 PF11882.8 KRZ98979.1 - 2.1 7.4 4.8 2.7 7.0 4.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3402) PXA PF02194.15 KRZ98980.1 - 1.3e-37 129.6 1.0 1.3e-37 129.6 1.0 2.8 3 0 0 3 3 3 1 PXA domain Nexin_C PF08628.12 KRZ98980.1 - 1e-18 67.9 0.1 8.7e-18 64.9 0.0 2.8 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.24 KRZ98980.1 - 4.3e-17 62.1 1.1 2.2e-16 59.9 0.6 2.6 2 0 0 2 2 2 1 PX domain RGS PF00615.19 KRZ98980.1 - 9.2e-16 58.2 1.6 9.2e-16 58.2 1.6 4.3 4 0 0 4 4 4 1 Regulator of G protein signaling domain G-patch PF01585.23 KRZ98981.1 - 5.1e-05 23.1 0.7 0.00023 21.0 0.7 2.2 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KRZ98981.1 - 0.029 14.4 0.3 0.029 14.4 0.3 3.8 2 1 0 2 2 2 0 G-patch domain CtaG_Cox11 PF04442.14 KRZ98981.1 - 1.2 9.1 5.7 0.39 10.7 0.2 2.7 2 1 1 3 3 3 0 Cytochrome c oxidase assembly protein CtaG/Cox11 Macoilin PF09726.9 KRZ98981.1 - 9.1 4.7 31.9 10 4.6 31.9 1.1 1 0 0 1 1 1 0 Macoilin family RRM_1 PF00076.22 KRZ98982.1 - 2.8e-39 132.8 2.2 2.7e-15 55.9 0.3 5.0 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KRZ98982.1 - 3.3e-25 87.7 0.3 2.4e-19 68.9 0.0 4.5 3 1 1 4 4 4 3 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 KRZ98982.1 - 0.005 16.8 0.0 3.9 7.5 0.0 3.2 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 KRZ98982.1 - 0.0058 16.7 0.3 0.45 10.7 0.0 3.9 4 0 0 4 4 4 1 RNA recognition motif Mad3_BUB1_I PF08311.12 KRZ98982.1 - 0.029 14.3 0.6 0.029 14.3 0.6 3.7 4 0 0 4 4 4 0 Mad3/BUB1 homology region 1 Nup35_RRM PF05172.13 KRZ98982.1 - 0.074 13.0 0.5 0.44 10.5 0.5 2.3 1 1 0 1 1 1 0 Nup53/35/40-type RNA recognition motif tRNA-synt_1 PF00133.22 KRZ98983.1 - 5.3e-47 160.4 0.1 2e-37 128.7 0.0 2.5 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 KRZ98983.1 - 7.9e-18 64.4 0.1 1.4e-09 37.2 0.0 3.3 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 KRZ98983.1 - 5.4e-12 45.9 0.0 1.7e-11 44.3 0.0 1.9 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 KRZ98983.1 - 2.6e-07 30.3 0.0 4.7e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1_2 PF13603.6 KRZ98983.1 - 0.025 14.1 0.0 0.085 12.4 0.0 1.9 1 1 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 CDC4_D PF16856.5 KRZ98984.1 - 1.5e-20 72.8 4.7 1.5e-20 72.8 4.7 2.6 3 0 0 3 3 3 1 Cell division control protein 4 dimerisation domain F-box PF00646.33 KRZ98984.1 - 1.1e-12 47.5 1.1 1.9e-12 46.7 1.1 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KRZ98984.1 - 1.5e-11 43.9 0.9 2.8e-11 43.1 0.9 1.5 1 0 0 1 1 1 1 F-box-like PRANC PF09372.10 KRZ98984.1 - 0.00038 20.7 1.3 0.0012 19.1 0.4 2.3 1 1 1 2 2 2 1 PRANC domain F-box_4 PF15966.5 KRZ98984.1 - 0.0012 18.7 0.2 0.0041 17.0 0.0 1.9 2 0 0 2 2 2 1 F-box WD40 PF00400.32 KRZ98984.1 - 0.025 15.4 0.3 0.16 12.9 0.1 2.4 2 0 0 2 2 2 0 WD domain, G-beta repeat TIP120 PF08623.10 KRZ98985.1 - 4.4e-39 133.9 0.6 4.4e-39 133.9 0.6 3.1 3 0 0 3 3 3 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.6 KRZ98985.1 - 2.1e-06 28.0 0.0 0.0054 17.1 0.0 3.5 4 0 0 4 4 4 2 HEAT repeats HEAT PF02985.22 KRZ98985.1 - 9.5e-06 25.4 1.2 0.22 11.9 0.0 5.5 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.6 KRZ98985.1 - 0.0048 17.4 0.0 28 5.3 0.0 4.3 3 0 0 3 3 3 1 HEAT-like repeat TAF6_C PF07571.13 KRZ98985.1 - 0.037 14.4 0.0 0.34 11.2 0.0 2.7 1 0 0 1 1 1 0 TAF6 C-terminal HEAT repeat domain DUF2373 PF10180.9 KRZ98986.1 - 1.7e-22 79.0 1.3 4.2e-22 77.8 1.3 1.7 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) Peptidase_M20 PF01546.28 KRZ98987.1 - 5e-19 68.8 0.1 1.4e-18 67.3 0.1 1.7 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KRZ98987.1 - 1.6e-18 66.6 0.0 2.7e-18 65.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Phage_int_SAM_5 PF13102.6 KRZ98988.1 - 0.022 15.1 0.5 0.035 14.4 0.5 1.4 1 0 0 1 1 1 0 Phage integrase SAM-like domain CDH1_2_SANT_HL1 PF18375.1 KRZ98988.1 - 0.089 13.5 0.7 0.089 13.5 0.7 1.7 2 0 0 2 2 2 0 CDH1/2 SANT-Helical linker 1 DUF4776 PF16003.5 KRZ98988.1 - 0.67 8.9 8.7 1.2 8.1 8.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4776) DUF4629 PF15442.6 KRZ98988.1 - 6.1 7.1 14.3 5.3 7.3 4.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4629) HAD PF12710.7 KRZ98990.1 - 2.4e-09 37.9 0.0 1.3e-08 35.5 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 KRZ98990.1 - 0.00012 21.7 0.2 0.00019 21.0 0.2 1.3 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) Hydrolase PF00702.26 KRZ98990.1 - 0.0036 17.6 0.0 0.0084 16.4 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 KRZ98990.1 - 0.0039 16.6 1.4 0.28 10.6 0.3 3.0 2 1 1 3 3 3 1 Putative Phosphatase TPR_1 PF00515.28 KRZ98991.1 - 7.1e-13 47.8 0.2 0.028 14.3 0.0 7.2 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.17 KRZ98991.1 - 1.7e-12 46.4 2.0 0.28 11.4 0.0 8.2 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.6 KRZ98991.1 - 2e-08 34.6 4.2 0.00072 20.0 0.1 5.1 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 KRZ98991.1 - 1.3e-06 28.7 13.9 1.2 10.2 0.0 8.2 7 2 2 9 9 8 2 Tetratricopeptide repeat TPR_12 PF13424.6 KRZ98991.1 - 8.7e-06 25.9 14.6 0.0038 17.5 0.5 5.7 6 2 1 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 KRZ98991.1 - 1.7e-05 24.9 12.5 5.8 7.5 0.0 7.5 9 0 0 9 9 6 1 Tetratricopeptide repeat TPR_9 PF13371.6 KRZ98991.1 - 1.8e-05 24.8 9.1 0.0086 16.2 0.2 5.4 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_15 PF13429.6 KRZ98991.1 - 4.4e-05 22.8 1.4 0.11 11.7 0.0 3.8 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 KRZ98991.1 - 6.5e-05 22.8 0.0 7.4 7.1 0.0 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 KRZ98991.1 - 0.00017 21.2 0.0 0.17 11.6 0.0 4.1 3 0 0 3 3 3 1 TPR repeat ANAPC3 PF12895.7 KRZ98991.1 - 0.00024 21.3 0.8 0.042 14.1 0.0 3.0 3 1 0 3 3 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 KRZ98991.1 - 0.016 15.9 15.5 1.5 9.5 3.2 6.3 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 KRZ98991.1 - 0.22 12.2 12.7 7.8 7.4 0.3 6.6 9 0 0 9 9 8 0 Tetratricopeptide repeat GTP_EFTU PF00009.27 KRZ98992.1 - 0.00058 19.4 0.0 0.015 14.9 0.1 2.3 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KRZ98992.1 - 0.00089 19.4 1.8 0.0048 17.0 1.8 2.2 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 KRZ98992.1 - 0.0014 18.7 1.5 0.012 15.6 1.5 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_7 PF12775.7 KRZ98992.1 - 0.045 13.3 0.1 0.093 12.2 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF5547 PF17701.1 KRZ98992.1 - 0.18 11.7 0.6 0.48 10.3 0.1 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5547) FidL_like PF15941.5 KRZ98993.1 - 1.5 9.3 5.8 0.34 11.4 0.7 2.6 2 1 1 3 3 3 0 FidL-like putative membrane protein RNB PF00773.19 KRZ98994.1 - 4.4e-47 161.0 1.5 4.4e-47 161.0 1.5 2.4 2 0 0 2 2 2 1 RNB domain SMC_N PF02463.19 KRZ98995.1 - 1.4e-63 214.3 33.4 4.6e-39 134.1 3.9 3.0 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KRZ98995.1 - 1.7e-18 67.0 2.6 6.6e-18 65.1 0.4 2.7 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 KRZ98995.1 - 1.2e-10 42.2 31.6 1.2e-10 42.2 31.6 7.4 2 2 2 4 4 4 1 AAA domain AAA_21 PF13304.6 KRZ98995.1 - 3.9e-08 33.5 0.2 5e-05 23.2 0.2 4.6 4 2 2 6 6 6 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KRZ98995.1 - 4.6e-05 23.3 17.8 4.6e-05 23.3 17.8 4.5 2 2 2 4 4 4 1 AAA ATPase domain AAA_29 PF13555.6 KRZ98995.1 - 7.8e-05 22.3 0.1 0.00019 21.1 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain BRX_N PF13713.6 KRZ98995.1 - 0.56 10.0 4.8 3.4 7.5 0.5 3.2 2 0 0 2 2 2 0 Transcription factor BRX N-terminal domain Anp1 PF03452.14 KRZ98996.1 - 8.7e-111 369.5 0.0 1.1e-110 369.2 0.0 1.1 1 0 0 1 1 1 1 Anp1 PQ-loop PF04193.14 KRZ98997.1 - 1.3e-29 101.7 2.9 6.3e-19 67.5 0.8 3.1 4 0 0 4 4 4 2 PQ loop repeat CLN3 PF02487.17 KRZ98997.1 - 0.015 14.3 0.0 0.029 13.4 0.0 1.4 2 0 0 2 2 2 0 CLN3 protein Connexin PF00029.19 KRZ98997.1 - 0.066 13.0 0.7 0.45 10.2 0.1 2.0 2 0 0 2 2 2 0 Connexin NicO PF03824.16 KRZ98997.1 - 0.46 9.8 6.8 0.76 9.1 6.8 1.3 1 0 0 1 1 1 0 High-affinity nickel-transport protein FAD_binding_1 PF00667.20 KRZ98998.1 - 3.3e-68 229.6 0.0 5.1e-68 229.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 KRZ98998.1 - 1.3e-07 32.2 0.0 3.1e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain PFOR_II PF17147.4 KRZ98998.1 - 0.027 14.8 0.0 0.069 13.5 0.0 1.7 1 0 0 1 1 1 0 Pyruvate:ferredoxin oxidoreductase core domain II WRNPLPNID PF15017.6 KRZ98998.1 - 0.039 14.8 0.6 2.8 8.9 1.3 2.6 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box FAD_binding_6 PF00970.24 KRZ98998.1 - 0.12 12.8 0.0 0.43 11.0 0.0 1.9 2 0 0 2 2 2 0 Oxidoreductase FAD-binding domain DUF1759 PF03564.15 KRZ98998.1 - 0.16 11.9 0.0 0.46 10.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1759) YL1_C PF08265.11 KRZ98999.1 - 2.5e-13 49.5 0.1 4.1e-13 48.8 0.1 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Sedlin_N PF04628.13 KRZ99000.1 - 6.2e-31 107.2 0.6 8.7e-31 106.8 0.6 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Alpha-amylase_C PF02806.18 KRZ99001.1 - 2.4e-25 88.8 0.2 9.3e-25 86.9 0.1 2.1 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.24 KRZ99001.1 - 5e-15 55.9 0.2 1.6e-13 51.0 0.0 2.3 1 1 1 2 2 2 1 Alpha amylase, catalytic domain Glyco_hydro_66 PF13199.6 KRZ99001.1 - 0.051 12.2 0.1 0.077 11.6 0.1 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 66 GHL6 PF14871.6 KRZ99001.1 - 0.12 12.5 0.0 0.31 11.2 0.0 1.7 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 Ric8 PF10165.9 KRZ99002.1 - 5.9e-17 61.8 6.9 1.1e-16 61.0 6.9 1.4 1 1 0 1 1 1 1 Guanine nucleotide exchange factor synembryn Fungal_trans_2 PF11951.8 KRZ99003.1 - 0.0001 21.3 0.4 0.00016 20.7 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain ARPC4 PF05856.12 KRZ99003.1 - 0.03 13.9 0.7 0.061 12.9 0.6 1.6 1 1 0 1 1 1 0 ARP2/3 complex 20 kDa subunit (ARPC4) Ku PF02735.16 KRZ99004.1 - 4e-27 95.3 0.0 1.2e-26 93.7 0.0 1.8 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 KRZ99004.1 - 7.5e-12 45.5 0.6 1.8e-11 44.2 0.6 1.6 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain DUF1924 PF09086.11 KRZ99004.1 - 0.13 12.6 0.0 0.36 11.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1924) MMR_HSR1 PF01926.23 KRZ99005.1 - 1.2e-13 51.1 0.1 5.2e-13 49.1 0.0 2.2 3 0 0 3 3 3 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KRZ99005.1 - 5.1e-05 22.9 0.5 0.0036 16.9 0.5 2.5 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KRZ99005.1 - 0.00075 19.4 1.1 0.0027 17.6 1.1 1.9 1 1 0 1 1 1 1 RsgA GTPase Septin PF00735.18 KRZ99005.1 - 0.0096 15.2 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 Septin AIG1 PF04548.16 KRZ99005.1 - 0.015 14.6 0.0 0.039 13.3 0.0 1.8 1 0 0 1 1 1 0 AIG1 family AAA_24 PF13479.6 KRZ99005.1 - 0.058 13.1 0.8 0.39 10.4 0.1 2.2 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 KRZ99005.1 - 0.087 12.9 0.3 20 5.2 0.0 3.0 1 1 1 2 2 2 0 Dynamin family Roc PF08477.13 KRZ99005.1 - 0.11 12.7 0.1 0.3 11.3 0.1 1.8 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_18 PF13238.6 KRZ99005.1 - 0.14 12.7 0.2 0.34 11.4 0.2 1.7 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.10 KRZ99006.1 - 5.7e-105 350.7 0.1 6.4e-105 350.5 0.1 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 KRZ99006.1 - 0.0032 17.6 0.0 0.0072 16.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KRZ99006.1 - 0.079 13.5 0.0 0.15 12.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain CLP1_P PF16575.5 KRZ99006.1 - 0.13 12.0 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Utp11 PF03998.13 KRZ99007.1 - 7.5e-66 222.6 42.0 8.7e-66 222.3 42.0 1.0 1 0 0 1 1 1 1 Utp11 protein SLATT_5 PF18160.1 KRZ99007.1 - 0.013 14.8 0.8 0.013 14.8 0.8 2.4 2 1 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 RsfS PF02410.15 KRZ99008.1 - 1.2e-21 77.0 0.0 2.6e-21 75.9 0.0 1.6 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation GIDE PF12483.8 KRZ99008.1 - 0.1 12.0 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 E3 Ubiquitin ligase Drc1-Sld2 PF11719.8 KRZ99009.1 - 2.5e-86 291.0 40.1 3.9e-86 290.4 40.1 1.3 1 1 0 1 1 1 1 DNA replication and checkpoint protein Hyphal_reg_CWP PF11765.8 KRZ99010.1 - 5.2e-80 268.8 16.5 5.2e-80 268.8 16.5 1.3 1 1 0 1 1 1 1 Hyphally regulated cell wall protein N-terminal Hyr1 PF15789.5 KRZ99010.1 - 0.23 11.0 6.2 0.58 9.8 5.1 2.4 2 0 0 2 2 2 0 Hyphally regulated cell wall GPI-anchored protein 1 ADH_zinc_N PF00107.26 KRZ99011.1 - 4.3e-12 46.1 0.1 1.2e-11 44.8 0.1 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KRZ99011.1 - 0.0024 18.9 0.2 0.03 15.4 0.1 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KRZ99011.1 - 0.0078 16.1 0.3 0.037 13.9 0.2 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain MFS_1 PF07690.16 KRZ99012.1 - 4.2e-36 124.6 26.5 4.2e-36 124.6 26.5 1.4 1 1 1 2 2 2 1 Major Facilitator Superfamily CRIC_ras_sig PF10534.9 KRZ99012.1 - 0.037 14.2 0.0 0.087 13.0 0.0 1.6 1 0 0 1 1 1 0 Connector enhancer of kinase suppressor of ras Trp_oprn_chp PF09534.10 KRZ99012.1 - 0.15 11.8 0.0 0.15 11.8 0.0 2.2 2 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF2951 PF11166.8 KRZ99012.1 - 2.8 8.2 4.8 0.82 9.9 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2951) LIDHydrolase PF10230.9 KRZ99013.1 - 6.8e-69 232.4 1.2 7.9e-69 232.2 1.2 1.0 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase DUF2570 PF10828.8 KRZ99013.1 - 0.083 12.7 0.6 0.16 11.8 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) TANGO2 PF05742.12 KRZ99014.1 - 2e-31 110.0 0.0 2.4e-31 109.7 0.0 1.0 1 0 0 1 1 1 1 Transport and Golgi organisation 2 TANGO2 PF05742.12 KRZ99015.1 - 5.4e-31 108.5 0.0 5.8e-31 108.5 0.0 1.0 1 0 0 1 1 1 1 Transport and Golgi organisation 2 Pkinase PF00069.25 KRZ99016.1 - 1.7e-46 158.7 0.0 1e-43 149.6 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KRZ99016.1 - 1.7e-25 89.8 0.0 2.3e-24 86.1 0.0 2.4 2 1 0 2 2 2 1 Protein tyrosine kinase BCMA-Tall_bind PF09257.10 KRZ99016.1 - 0.11 12.7 0.3 1.7 8.8 0.0 2.5 2 0 0 2 2 2 0 BCMA, TALL-1 binding zf-CCCH PF00642.24 KRZ99017.1 - 1.1e-09 38.0 26.1 0.00019 21.3 2.5 4.9 4 1 1 5 5 5 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KRZ99017.1 - 3.7e-06 26.8 27.8 0.0047 16.9 1.7 5.7 5 1 0 5 5 5 3 Zinc finger domain zf-CCCH_4 PF18044.1 KRZ99017.1 - 0.00019 21.2 28.0 0.15 11.9 0.1 5.6 5 1 0 5 5 5 3 CCCH-type zinc finger zf-CCCH_3 PF15663.5 KRZ99017.1 - 0.97 9.7 14.8 2 8.6 8.5 3.6 1 1 3 4 4 4 0 Zinc-finger containing family zf-C2HC5 PF06221.13 KRZ99018.1 - 1.1e-23 82.9 5.0 1.9e-23 82.2 5.0 1.4 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type DUF2292 PF10055.9 KRZ99018.1 - 0.1 12.2 0.2 0.24 11.1 0.2 1.6 1 0 0 1 1 1 0 Uncharacterized small protein (DUF2292) TxDE PF18711.1 KRZ99018.1 - 0.15 12.2 0.0 0.67 10.1 0.0 2.0 2 0 0 2 2 2 0 Toxoflavin-degrading enzyme TetR_C_23 PF17931.1 KRZ99018.1 - 9.2 6.4 9.7 16 5.6 2.1 2.9 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain adh_short PF00106.25 KRZ99019.1 - 3.4e-35 121.3 1.5 4.3e-35 120.9 1.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KRZ99019.1 - 1.8e-33 116.0 0.2 2.3e-33 115.7 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KRZ99019.1 - 1.7e-13 50.9 0.3 2.2e-13 50.5 0.3 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KRZ99019.1 - 1.4e-05 25.1 0.7 2.7e-05 24.2 0.7 1.5 1 1 0 1 1 1 1 NAD(P)H-binding F420_oxidored PF03807.17 KRZ99019.1 - 0.00079 20.0 0.9 0.0025 18.4 0.1 2.2 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.15 KRZ99019.1 - 0.0083 15.3 0.5 0.012 14.7 0.5 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein tRNA-synt_1e PF01406.19 KRZ99019.1 - 0.009 15.4 0.0 0.013 14.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Epimerase PF01370.21 KRZ99019.1 - 0.028 13.9 0.3 0.057 12.9 0.2 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF4325 PF14213.6 KRZ99019.1 - 0.055 13.2 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 STAS-like domain of unknown function (DUF4325) PRMT5 PF05185.16 KRZ99019.1 - 0.062 13.2 0.1 0.13 12.1 0.1 1.5 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Glyco_trans_4_2 PF13477.6 KRZ99019.1 - 0.1 12.6 0.1 0.47 10.5 0.1 1.9 2 0 0 2 2 2 0 Glycosyl transferase 4-like Fungal_trans_2 PF11951.8 KRZ99020.1 - 5.2e-18 65.0 2.1 1e-17 64.0 0.1 2.3 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KRZ99020.1 - 1.2e-07 31.7 12.1 3.2e-07 30.4 12.1 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dak1 PF02733.17 KRZ99021.1 - 6.8e-111 370.1 0.6 8.4e-111 369.8 0.6 1.0 1 0 0 1 1 1 1 Dak1 domain Not3 PF04065.15 KRZ99022.1 - 2.3e-27 95.9 5.6 4.9e-27 94.8 5.6 1.5 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 KRZ99022.1 - 0.00026 21.1 9.4 0.0099 16.0 0.4 3.1 3 0 0 3 3 3 2 NOT2 / NOT3 / NOT5 family CLZ PF16526.5 KRZ99022.1 - 0.09 13.1 0.9 0.21 11.9 0.9 1.6 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Pex2_Pex12 PF04757.14 KRZ99024.1 - 3e-50 170.9 14.2 3.8e-50 170.6 14.2 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.6 KRZ99024.1 - 1.6e-06 28.2 2.7 2.8e-06 27.4 2.7 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 KRZ99024.1 - 1.8e-05 24.4 1.3 2.4e-05 24.1 0.5 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KRZ99024.1 - 4.4e-05 23.3 0.3 7.6e-05 22.5 0.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KRZ99024.1 - 0.00012 22.1 0.7 0.00025 21.0 0.7 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KRZ99024.1 - 0.0014 18.5 0.9 0.0025 17.7 0.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KRZ99024.1 - 0.008 16.5 0.6 0.016 15.5 0.6 1.5 1 0 0 1 1 1 1 Ring finger domain IF-2B PF01008.17 KRZ99025.1 - 9.8e-58 195.6 0.1 1.7e-57 194.8 0.1 1.3 1 0 0 1 1 1 1 Initiation factor 2 subunit family Vps54 PF07928.12 KRZ99026.1 - 8.3e-38 129.9 1.9 8.3e-38 129.9 1.9 2.9 3 0 0 3 3 3 1 Vps54-like protein CSN8_PSD8_EIF3K PF10075.9 KRZ99026.1 - 0.051 13.6 0.5 0.35 10.8 0.1 2.4 2 0 0 2 2 2 0 CSN8/PSMD8/EIF3K family COG2 PF06148.11 KRZ99026.1 - 1.5 8.9 10.1 0.31 11.1 4.0 2.8 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 RseA_N PF03872.13 KRZ99026.1 - 9.6 6.8 8.2 56 4.3 1.0 4.0 4 1 0 4 4 4 0 Anti sigma-E protein RseA, N-terminal domain COX17 PF05051.13 KRZ99027.1 - 2.3e-22 79.1 6.5 3.1e-22 78.7 6.5 1.2 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) CHCH PF06747.13 KRZ99027.1 - 0.00061 19.9 3.7 0.00097 19.2 3.7 1.4 1 0 0 1 1 1 1 CHCH domain STIMATE PF12400.8 KRZ99028.1 - 2e-37 128.6 8.4 3.9e-37 127.6 8.4 1.5 1 0 0 1 1 1 1 STIMATE family Cys_Met_Meta_PP PF01053.20 KRZ99029.1 - 3.3e-67 226.7 0.0 1.1e-66 225.0 0.0 1.7 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KRZ99029.1 - 0.0002 20.6 0.0 0.001 18.3 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KRZ99029.1 - 0.00083 18.4 0.0 0.0014 17.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DUF1752 PF08550.10 KRZ99030.1 - 1.4e-12 47.2 3.1 3.1e-12 46.1 3.1 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) RRN3 PF05327.11 KRZ99031.1 - 0.0039 15.8 8.2 0.0045 15.6 8.2 1.1 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 PBP1_TM PF14812.6 KRZ99031.1 - 0.006 16.9 4.1 0.0095 16.3 4.1 1.4 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.10 KRZ99031.1 - 0.0081 16.5 4.9 0.011 16.1 4.9 1.3 1 0 0 1 1 1 1 Centromere protein B dimerisation domain GP24_25 PF17388.2 KRZ99031.1 - 0.021 14.8 0.5 0.034 14.1 0.5 1.3 1 0 0 1 1 1 0 Tail assembly gene products 24 & 25 Sporozoite_P67 PF05642.11 KRZ99031.1 - 0.1 10.6 2.4 0.1 10.7 2.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Cwf_Cwc_15 PF04889.12 KRZ99031.1 - 0.13 12.0 8.6 0.15 11.8 8.6 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 KRZ99031.1 - 0.59 9.4 8.7 0.76 9.0 8.7 1.2 1 0 0 1 1 1 0 NOA36 protein Pox_Ag35 PF03286.14 KRZ99031.1 - 0.74 9.6 8.0 1 9.1 8.0 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF2457 PF10446.9 KRZ99031.1 - 1.3 8.1 10.4 1.7 7.7 10.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF3245 PF11595.8 KRZ99031.1 - 1.3 9.5 7.1 0.25 11.8 3.8 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) FAM176 PF14851.6 KRZ99031.1 - 8.4 6.0 7.9 12 5.5 7.6 1.4 1 1 0 1 1 1 0 FAM176 family Sugar_tr PF00083.24 KRZ99032.1 - 1.3e-64 218.7 25.6 1.6e-64 218.5 25.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KRZ99032.1 - 5.3e-21 74.9 27.0 3.3e-17 62.5 18.5 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily Bac_rhamnosid6H PF17389.2 KRZ99034.1 - 2.5e-13 50.0 0.1 8.6e-13 48.3 0.1 1.7 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Trehalase PF01204.18 KRZ99034.1 - 1.3e-09 37.4 0.0 2e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Trehalase Glyco_hydro_36 PF17167.4 KRZ99034.1 - 0.00065 18.5 0.3 0.0021 16.9 0.3 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase 36 superfamily, catalytic domain DHDPS PF00701.22 KRZ99035.1 - 3e-25 88.5 0.0 3.3e-25 88.4 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Amidohydro_2 PF04909.14 KRZ99036.1 - 3.7e-14 53.2 0.1 1.9e-13 50.9 0.0 1.9 2 0 0 2 2 2 1 Amidohydrolase adh_short_C2 PF13561.6 KRZ99037.1 - 5.1e-62 209.5 0.0 6.2e-62 209.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KRZ99037.1 - 3.9e-46 157.0 0.3 4.8e-46 156.7 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KRZ99037.1 - 1.2e-10 41.6 0.1 1.7e-10 41.1 0.1 1.2 1 0 0 1 1 1 1 KR domain Sybindin PF04099.12 KRZ99037.1 - 0.02 14.8 0.0 0.034 14.1 0.0 1.3 1 0 0 1 1 1 0 Sybindin-like family THF_DHG_CYH_C PF02882.19 KRZ99037.1 - 0.089 12.1 0.1 0.25 10.6 0.0 1.7 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF3670 PF12419.8 KRZ99037.1 - 0.16 11.8 0.0 0.32 10.8 0.0 1.4 1 0 0 1 1 1 0 SNF2 Helicase protein MR_MLE_C PF13378.6 KRZ99038.1 - 2.9e-45 154.5 0.0 3.8e-45 154.1 0.0 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KRZ99038.1 - 2.6e-09 37.3 0.0 4.3e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Sugar_tr PF00083.24 KRZ99039.1 - 1.4e-99 334.0 32.9 1.8e-99 333.7 32.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KRZ99039.1 - 5.6e-20 71.6 48.3 2.8e-17 62.7 24.0 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4007 PF13182.6 KRZ99040.1 - 0.036 13.2 0.1 0.041 13.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4007) Sugar_tr PF00083.24 KRZ99041.1 - 1e-102 344.3 27.9 1.3e-102 344.0 27.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KRZ99041.1 - 5.8e-22 78.1 31.9 1.8e-21 76.5 27.6 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Phage_holin_3_2 PF04550.12 KRZ99041.1 - 0.15 12.6 2.1 0.38 11.3 2.1 1.7 1 0 0 1 1 1 0 Phage holin family 2 SurE PF01975.17 KRZ99042.1 - 1.7e-39 135.6 0.0 2.3e-39 135.2 0.0 1.1 1 0 0 1 1 1 1 Survival protein SurE ADH_N PF08240.12 KRZ99043.1 - 1.3e-26 92.6 3.7 2.8e-26 91.5 3.7 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KRZ99043.1 - 7.6e-15 55.0 0.0 1.1e-14 54.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KRZ99043.1 - 2.3e-07 30.6 0.1 8.6e-05 22.1 0.0 2.3 2 0 0 2 2 2 2 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KRZ99043.1 - 3.9e-05 24.7 0.0 6.7e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.14 KRZ99043.1 - 0.0026 17.4 0.1 0.0047 16.5 0.1 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sacchrp_dh_NADP PF03435.18 KRZ99043.1 - 0.035 14.4 0.1 0.056 13.7 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 KRZ99043.1 - 0.036 14.3 0.1 0.064 13.5 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain Arabinose_bd PF12625.7 KRZ99043.1 - 0.052 13.6 0.0 9.8 6.2 0.0 2.2 2 0 0 2 2 2 0 Arabinose-binding domain of AraC transcription regulator, N-term DapB_N PF01113.20 KRZ99043.1 - 0.054 13.6 0.2 0.092 12.9 0.2 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DUF637 PF04830.13 KRZ99044.1 - 0.073 12.9 0.2 0.17 11.7 0.2 1.6 1 0 0 1 1 1 0 Possible hemagglutinin (DUF637) HHH_8 PF14716.6 KRZ99044.1 - 0.11 12.9 0.1 0.27 11.6 0.1 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain PGAP1 PF07819.13 KRZ99044.1 - 0.11 12.2 0.0 0.35 10.5 0.0 1.8 2 0 0 2 2 2 0 PGAP1-like protein Pox_P4A PF03395.14 KRZ99044.1 - 0.2 9.2 0.6 0.28 8.7 0.6 1.1 1 0 0 1 1 1 0 Poxvirus P4A protein ACOX PF01756.19 KRZ99045.1 - 1.6e-42 145.1 0.1 3e-42 144.2 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 KRZ99045.1 - 6e-23 80.9 0.1 1e-22 80.1 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.6 KRZ99045.1 - 1.8e-13 51.2 0.1 4.2e-13 50.0 0.1 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.24 KRZ99045.1 - 7.7e-05 22.9 0.2 0.00052 20.2 0.0 2.3 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain p450 PF00067.22 KRZ99046.1 - 4.4e-63 213.6 0.7 5.6e-63 213.3 0.7 1.0 1 0 0 1 1 1 1 Cytochrome P450 cobW PF02492.19 KRZ99048.1 - 1.2e-46 158.5 6.1 1.9e-44 151.4 6.1 2.2 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 KRZ99048.1 - 8.2e-17 60.9 0.0 2.3e-12 46.7 0.0 2.4 2 0 0 2 2 2 2 Cobalamin synthesis protein cobW C-terminal domain AAA_16 PF13191.6 KRZ99048.1 - 0.023 15.1 0.0 0.057 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain MobB PF03205.14 KRZ99048.1 - 0.062 13.2 0.2 0.16 11.8 0.2 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B T2SSE PF00437.20 KRZ99048.1 - 0.072 12.1 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Viral_helicase1 PF01443.18 KRZ99048.1 - 0.095 12.4 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA PF00004.29 KRZ99048.1 - 0.15 12.5 0.5 6.2 7.3 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 KRZ99048.1 - 0.16 11.8 0.9 0.31 10.8 0.1 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain PhzC-PhzF PF02567.16 KRZ99049.1 - 4.7e-71 239.5 0.0 5.3e-71 239.4 0.0 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Pro_racemase PF05544.11 KRZ99049.1 - 6.6e-06 25.4 0.0 9.7e-06 24.9 0.0 1.2 1 0 0 1 1 1 1 Proline racemase CAP_GLY PF01302.25 KRZ99050.1 - 7.4e-14 51.5 0.2 1.3e-13 50.7 0.2 1.4 1 0 0 1 1 1 1 CAP-Gly domain FAM76 PF16046.5 KRZ99050.1 - 8.9e-05 22.0 14.7 8.9e-05 22.0 14.7 3.2 1 1 2 3 3 3 1 FAM76 protein CLIP1_ZNF PF16641.5 KRZ99050.1 - 0.0054 16.6 1.0 0.0092 15.8 1.0 1.4 1 0 0 1 1 1 1 CLIP1 zinc knuckle Spc7 PF08317.11 KRZ99050.1 - 0.0055 15.6 23.2 0.0055 15.6 23.2 3.2 1 1 2 3 3 3 1 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 KRZ99050.1 - 0.01 15.9 6.9 0.01 15.9 6.9 5.5 1 1 3 5 5 5 0 TPR/MLP1/MLP2-like protein Lebercilin PF15619.6 KRZ99050.1 - 1.3 8.6 67.2 0.5 10.0 15.5 4.6 1 1 4 5 5 5 0 Ciliary protein causing Leber congenital amaurosis disease DUF4407 PF14362.6 KRZ99050.1 - 2.3 7.5 37.7 0.066 12.6 11.2 3.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) DUF2533 PF10752.9 KRZ99050.1 - 5 7.6 7.1 3.6 8.1 2.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2533) Fez1 PF06818.15 KRZ99050.1 - 5.6 7.4 60.2 0.55 10.7 24.6 3.8 1 1 2 3 3 3 0 Fez1 Zn_clus PF00172.18 KRZ99052.1 - 1.1e-06 28.7 8.5 2.3e-06 27.6 8.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KRZ99052.1 - 1.7e-06 27.3 6.2 3.1e-06 26.4 5.3 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Arv1 PF04161.13 KRZ99052.1 - 0.0082 16.3 3.4 0.024 14.8 3.4 1.8 1 0 0 1 1 1 1 Arv1-like family bZIP_1 PF00170.21 KRZ99052.1 - 0.034 14.2 0.7 0.18 11.9 0.1 2.4 2 0 0 2 2 2 0 bZIP transcription factor DivIC PF04977.15 KRZ99052.1 - 0.077 12.8 0.0 0.4 10.5 0.0 2.1 2 0 0 2 2 2 0 Septum formation initiator IlvN PF07991.12 KRZ99053.1 - 1.1e-44 151.9 0.0 1.7e-44 151.3 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 KRZ99053.1 - 2.1e-41 141.5 0.0 4.3e-41 140.6 0.0 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain Pkinase PF00069.25 KRZ99054.1 - 7.4e-50 169.8 0.4 1e-49 169.3 0.4 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KRZ99054.1 - 3.5e-30 105.2 0.0 6.2e-30 104.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KRZ99054.1 - 0.0022 17.4 0.0 0.015 14.7 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KRZ99054.1 - 0.16 11.9 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family GSHPx PF00255.19 KRZ99055.1 - 1.1e-46 156.8 0.1 1.5e-46 156.4 0.1 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 KRZ99055.1 - 2.8e-05 24.0 0.1 0.0003 20.7 0.1 2.1 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KRZ99055.1 - 0.0003 20.5 0.1 0.0036 17.0 0.1 2.1 1 1 0 1 1 1 1 Redoxin DUF4174 PF13778.6 KRZ99055.1 - 0.15 12.6 0.0 0.23 11.9 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4174) CRA PF06589.11 KRZ99056.1 - 0.081 13.0 0.8 0.22 11.7 0.2 1.9 2 0 0 2 2 2 0 Circumsporozoite-related antigen (CRA) Pox_RNA_Pol_19 PF05320.12 KRZ99056.1 - 0.11 12.5 1.5 0.17 11.9 1.5 1.2 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit DUF2443 PF10398.9 KRZ99056.1 - 0.19 11.8 1.1 12 6.0 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2443) Y_phosphatase2 PF03162.13 KRZ99057.1 - 6.5e-51 172.2 0.0 8e-51 171.9 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 KRZ99057.1 - 1.5e-07 31.6 0.0 2.6e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 KRZ99057.1 - 0.0037 17.1 0.0 0.0054 16.5 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 KRZ99057.1 - 0.13 12.3 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate DAD PF02109.16 KRZ99058.1 - 1.7e-43 147.3 5.4 1e-42 144.8 5.4 1.9 1 1 0 1 1 1 1 DAD family S_4TM PF18159.1 KRZ99058.1 - 0.15 11.3 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 SMODS-associating 4TM effector domain Ras PF00071.22 KRZ99059.1 - 2.3e-57 193.1 0.0 2.9e-57 192.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KRZ99059.1 - 4.3e-21 75.4 0.0 7.5e-21 74.6 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KRZ99059.1 - 5.5e-08 32.4 0.0 6.8e-08 32.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KRZ99059.1 - 9e-05 22.1 0.0 0.00075 19.1 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KRZ99059.1 - 0.00027 20.9 0.6 0.69 9.8 0.3 2.7 1 1 2 3 3 3 2 RsgA GTPase MMR_HSR1 PF01926.23 KRZ99059.1 - 0.0014 18.7 0.0 0.0023 18.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF4943 PF16301.5 KRZ99059.1 - 0.038 14.0 0.0 0.067 13.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4943) MMR_HSR1_Xtn PF16897.5 KRZ99059.1 - 0.15 12.1 0.0 0.55 10.3 0.0 1.8 1 1 1 2 2 2 0 C-terminal region of MMR_HSR1 domain ING PF12998.7 KRZ99060.1 - 5.7e-27 94.3 0.6 5.7e-27 94.3 0.6 2.3 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 KRZ99060.1 - 4e-05 23.4 7.4 7.3e-05 22.6 7.4 1.5 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 KRZ99060.1 - 0.03 14.6 0.2 0.093 13.0 0.2 1.8 1 0 0 1 1 1 0 PHD-like zinc-binding domain PHD_2 PF13831.6 KRZ99060.1 - 0.036 13.6 1.7 0.066 12.8 1.7 1.5 1 0 0 1 1 1 0 PHD-finger Snf7 PF03357.21 KRZ99060.1 - 1.7 8.2 10.2 3.1 7.4 0.7 2.5 3 0 0 3 3 3 0 Snf7 zf-C2H2 PF00096.26 KRZ99061.1 - 4.1e-09 36.4 6.0 0.00047 20.5 3.1 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KRZ99061.1 - 7.1e-08 32.7 4.7 0.01 16.6 2.3 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 KRZ99061.1 - 0.0024 18.5 1.5 0.0097 16.6 0.5 2.3 2 0 0 2 2 2 1 Zinc finger C2H2-type, 3 repeats zf-C2H2_jaz PF12171.8 KRZ99061.1 - 0.041 14.2 1.6 0.63 10.4 0.0 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KRZ99061.1 - 0.074 13.5 0.5 1.3 9.6 0.0 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 KRZ99061.1 - 0.17 12.4 4.1 1.3 9.5 0.1 2.9 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_6 PF13912.6 KRZ99061.1 - 0.68 10.0 5.4 18 5.5 0.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger NuDC PF16273.5 KRZ99061.1 - 2 9.0 6.5 1.6 9.4 2.6 2.3 2 0 0 2 2 2 0 Nuclear distribution C domain NAD_Gly3P_dh_N PF01210.23 KRZ99062.1 - 1.8e-25 89.8 0.4 2.6e-25 89.2 0.1 1.4 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.17 KRZ99062.1 - 0.026 15.1 0.0 0.038 14.6 0.0 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Cas9_C PF18525.1 KRZ99062.1 - 0.036 14.2 0.0 0.053 13.7 0.0 1.3 1 0 0 1 1 1 0 Cas9 C-terminal domain Shikimate_DH PF01488.20 KRZ99062.1 - 0.064 13.3 0.0 0.091 12.8 0.0 1.4 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 KRZ99062.1 - 0.12 12.3 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RNA_ligase PF09414.10 KRZ99062.1 - 0.13 12.6 0.0 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 RNA ligase DUF4466 PF14725.6 KRZ99062.1 - 0.14 11.7 0.0 0.16 11.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4466) CybS PF05328.12 KRZ99063.1 - 4.5e-56 188.2 0.0 5.3e-56 188.0 0.0 1.0 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit RRM_1 PF00076.22 KRZ99064.1 - 0.11 12.3 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Methyltransf_1N PF02870.15 KRZ99064.1 - 0.43 11.4 3.7 5.7 7.8 1.7 2.5 1 1 0 2 2 2 0 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain PPP4R2 PF09184.11 KRZ99065.1 - 0.007 16.0 25.9 0.059 13.0 25.9 2.3 1 1 0 1 1 1 1 PPP4R2 FAM27 PF15832.5 KRZ99065.1 - 0.045 14.3 1.0 0.089 13.3 1.0 1.5 1 0 0 1 1 1 0 FAM27 D and E protein family Ribosomal_S7 PF00177.21 KRZ99066.1 - 6.9e-35 119.9 0.4 1.2e-34 119.1 0.4 1.4 2 0 0 2 2 2 1 Ribosomal protein S7p/S5e Flp_C PF05202.12 KRZ99066.1 - 0.007 15.9 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 Recombinase Flp protein Adap_comp_sub PF00928.21 KRZ99068.1 - 4.7e-86 288.4 1.3 6.9e-86 287.9 1.3 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KRZ99068.1 - 7.6e-10 38.9 5.8 1.3e-09 38.2 4.4 2.0 1 1 1 2 2 2 1 Clathrin adaptor complex small chain DUF2458 PF10454.9 KRZ99069.1 - 2.7e-10 40.2 1.2 2.7e-10 40.2 1.2 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2458) DGCR6 PF07324.11 KRZ99069.1 - 9.1e-05 22.2 4.2 9.1e-05 22.2 4.2 1.8 2 0 0 2 2 2 1 DiGeorge syndrome critical region 6 (DGCR6) protein ILVD_EDD PF00920.21 KRZ99070.1 - 1.3e-208 693.9 0.2 1.4e-208 693.7 0.2 1.0 1 0 0 1 1 1 1 Dehydratase family UQ_con PF00179.26 KRZ99071.1 - 4.5e-38 130.1 0.5 1.1e-37 128.8 0.5 1.7 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KRZ99071.1 - 0.022 14.5 0.0 0.056 13.1 0.0 1.6 1 0 0 1 1 1 0 Prokaryotic E2 family B DUF4141 PF13605.6 KRZ99071.1 - 0.1 11.8 1.7 0.22 10.8 1.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4141) YtxH PF12732.7 KRZ99071.1 - 0.36 11.4 5.5 21 5.8 3.4 3.6 2 1 0 2 2 2 0 YtxH-like protein DUF948 PF06103.11 KRZ99071.1 - 6.2 7.2 5.9 1.6 9.0 1.1 2.5 2 2 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Methyltransf_31 PF13847.6 KRZ99072.1 - 1.3e-30 106.2 0.0 1.9e-30 105.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KRZ99072.1 - 3.7e-21 75.6 0.0 7.5e-21 74.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KRZ99072.1 - 1.7e-19 70.2 0.0 4.6e-19 68.9 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KRZ99072.1 - 5.6e-16 58.6 0.2 1.2e-15 57.5 0.2 1.6 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KRZ99072.1 - 5.5e-11 42.6 0.0 1.2e-10 41.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KRZ99072.1 - 4e-09 37.1 0.0 7.6e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KRZ99072.1 - 4.8e-09 36.0 0.5 8.1e-09 35.3 0.4 1.4 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 KRZ99072.1 - 1.2e-08 35.0 0.0 2e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_2 PF00891.18 KRZ99072.1 - 3.2e-06 26.6 0.0 4.4e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase domain CMAS PF02353.20 KRZ99072.1 - 2.9e-05 23.5 0.0 4.4e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_8 PF05148.15 KRZ99072.1 - 0.00035 20.5 0.3 0.0009 19.2 0.0 1.8 2 1 0 2 2 2 1 Hypothetical methyltransferase UPF0020 PF01170.18 KRZ99072.1 - 0.00063 19.5 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_32 PF13679.6 KRZ99072.1 - 0.0015 18.6 0.0 0.0023 17.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 KRZ99072.1 - 0.0034 16.9 0.4 0.0073 15.9 0.1 1.7 2 0 0 2 2 2 1 Histone methylation protein DOT1 GidB PF02527.15 KRZ99072.1 - 0.051 12.9 0.0 0.086 12.2 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_4 PF02390.17 KRZ99072.1 - 0.086 12.3 0.2 0.3 10.5 0.1 1.9 2 0 0 2 2 2 0 Putative methyltransferase SBF PF01758.16 KRZ99073.1 - 4.5e-52 176.6 11.8 4.5e-52 176.6 11.8 1.7 2 0 0 2 2 2 1 Sodium Bile acid symporter family Rhodanese PF00581.20 KRZ99074.1 - 8.6e-07 29.4 0.0 1.1e-06 29.1 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain EB1 PF03271.17 KRZ99075.1 - 3e-13 49.8 2.5 3e-13 49.8 2.5 1.8 2 0 0 2 2 2 1 EB1-like C-terminal motif CH PF00307.31 KRZ99075.1 - 6.6e-09 35.9 0.5 1.2e-08 35.1 0.5 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain Sec2p PF06428.11 KRZ99075.1 - 0.0034 17.3 0.3 0.0099 15.8 0.3 1.7 1 0 0 1 1 1 1 GDP/GTP exchange factor Sec2p MscS_porin PF12795.7 KRZ99075.1 - 0.0065 16.0 1.6 0.01 15.4 1.6 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain zf-C4H2 PF10146.9 KRZ99075.1 - 0.041 14.2 3.3 0.047 14.0 2.5 1.4 1 1 0 1 1 1 0 Zinc finger-containing protein Cep57_CLD_2 PF14197.6 KRZ99075.1 - 0.47 10.6 4.3 1 9.5 4.3 1.6 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 Prefoldin_2 PF01920.20 KRZ99075.1 - 1.3 9.0 7.2 0.93 9.5 2.5 2.3 1 1 1 2 2 2 0 Prefoldin subunit Lyase_1 PF00206.20 KRZ99076.1 - 2.9e-24 86.0 0.0 4.1e-24 85.5 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 KRZ99076.1 - 2.8e-17 63.0 0.0 1.1e-16 61.1 0.0 2.1 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus Skp1 PF01466.19 KRZ99076.1 - 0.076 13.1 1.8 0.19 11.9 1.0 2.0 2 0 0 2 2 2 0 Skp1 family, dimerisation domain DUF1331 PF07048.11 KRZ99076.1 - 0.079 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1331) DASH_Dad3 PF08656.10 KRZ99077.1 - 7.7e-28 96.4 1.1 1.1e-27 95.9 1.1 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad3 COG6 PF06419.11 KRZ99077.1 - 0.0044 15.3 0.7 0.005 15.1 0.7 1.2 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 DASH_Spc19 PF08287.11 KRZ99077.1 - 1.2 9.0 8.4 0.12 12.2 0.5 2.0 1 1 0 2 2 2 0 Spc19 UPF0121 PF03661.13 KRZ99078.1 - 2.8e-06 26.9 14.7 0.00022 20.7 7.6 2.1 1 1 1 2 2 2 2 Uncharacterised protein family (UPF0121) DUF5542 PF17696.1 KRZ99078.1 - 0.17 12.1 2.8 0.34 11.1 0.0 2.6 3 0 0 3 3 3 0 Family of unknown function (DUF5542) Orf78 PF06024.12 KRZ99078.1 - 6.2 7.2 5.7 14 6.0 1.6 2.6 2 1 1 3 3 3 0 Orf78 (ac78) WD40 PF00400.32 KRZ99079.1 - 1.1e-15 57.7 15.4 1.5e-06 28.8 0.1 6.1 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KRZ99079.1 - 1.8e-07 31.3 0.1 0.0057 16.9 0.0 4.9 4 1 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KRZ99079.1 - 0.0032 17.4 3.6 0.15 12.0 0.1 4.0 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KRZ99079.1 - 0.016 14.2 0.0 2.7 6.9 0.0 3.3 3 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Cation_efflux PF01545.21 KRZ99080.1 - 2e-24 86.4 11.8 2.6e-24 86.0 11.8 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KRZ99080.1 - 1.5e-05 25.0 0.1 3.9e-05 23.7 0.1 1.6 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter SUR7 PF06687.12 KRZ99080.1 - 0.0006 19.5 1.2 0.002 17.8 0.1 2.4 3 0 0 3 3 3 1 SUR7/PalI family SPX PF03105.19 KRZ99081.1 - 4.8 7.0 13.0 6.4 6.6 13.0 1.2 1 0 0 1 1 1 0 SPX domain Zn_clus PF00172.18 KRZ99082.1 - 9.2e-06 25.7 8.4 9.2e-06 25.7 8.4 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TEX12 PF15219.6 KRZ99082.1 - 0.49 10.7 2.6 19 5.7 0.1 3.2 3 0 0 3 3 3 0 Testis-expressed 12 Dynamitin PF04912.14 KRZ99084.1 - 0.083 12.2 13.1 0.14 11.5 13.1 1.3 1 0 0 1 1 1 0 Dynamitin PGI PF00342.19 KRZ99085.1 - 2.4e-245 814.7 3.4 2.7e-245 814.5 3.4 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase Mhr1 PF12829.7 KRZ99085.1 - 0.0014 18.7 0.1 0.98 9.5 0.0 2.5 2 0 0 2 2 2 2 Transcriptional regulation of mitochondrial recombination CbiK PF06180.11 KRZ99085.1 - 0.079 12.3 0.8 0.12 11.6 0.8 1.2 1 0 0 1 1 1 0 Cobalt chelatase (CbiK) Put_Phosphatase PF06888.12 KRZ99085.1 - 0.31 10.4 2.1 1.1 8.6 0.6 2.1 2 0 0 2 2 2 0 Putative Phosphatase CRISPR_Cas9_WED PF18061.1 KRZ99085.1 - 2.5 8.2 6.4 7.4 6.7 0.6 2.9 2 1 1 3 3 3 0 CRISPR-Cas9 WED domain DUF1892 PF08987.10 KRZ99086.1 - 2.6e-16 59.8 1.6 2.6e-16 59.8 1.6 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF1892) DUF365 PF04033.12 KRZ99086.1 - 0.0036 17.5 0.7 0.018 15.3 0.0 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF365) PDCD2_C PF04194.13 KRZ99086.1 - 0.025 14.7 1.2 0.081 13.0 0.0 1.8 1 1 1 2 2 2 0 Programmed cell death protein 2, C-terminal putative domain P16-Arc PF04699.14 KRZ99087.1 - 2.6e-47 161.1 0.0 2.9e-47 160.9 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) DUF948 PF06103.11 KRZ99088.1 - 0.024 14.9 0.5 0.024 14.9 0.5 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) TolA_bind_tri PF16331.5 KRZ99088.1 - 0.043 13.9 3.1 0.7 10.0 1.2 2.6 2 1 1 3 3 3 0 TolA binding protein trimerisation YlqD PF11068.8 KRZ99088.1 - 0.06 13.7 12.5 0.11 12.9 4.1 2.1 2 0 0 2 2 2 0 YlqD protein SlyX PF04102.12 KRZ99088.1 - 0.15 12.7 0.7 0.4 11.3 0.7 1.8 1 0 0 1 1 1 0 SlyX Spectrin PF00435.21 KRZ99088.1 - 0.46 11.0 6.7 0.068 13.7 2.1 1.9 2 0 0 2 2 2 0 Spectrin repeat HIP1_clath_bdg PF16515.5 KRZ99088.1 - 1.2 9.7 13.0 0.82 10.3 3.5 3.0 2 1 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Tup_N PF08581.10 KRZ99088.1 - 1.5 9.2 10.7 0.14 12.5 5.7 1.8 2 0 0 2 2 2 0 Tup N-terminal APG6_N PF17675.1 KRZ99088.1 - 10 6.7 14.5 0.7 10.4 7.0 2.3 1 1 0 2 2 2 0 Apg6 coiled-coil region zf-C3HC4_2 PF13923.6 KRZ99090.1 - 2.8e-10 39.9 11.0 2.8e-10 39.9 11.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) SAP PF02037.27 KRZ99090.1 - 4.2e-07 29.6 0.1 2.9e-06 26.9 0.0 2.3 2 0 0 2 2 2 1 SAP domain zf-C3HC4 PF00097.25 KRZ99090.1 - 4.3e-07 29.7 13.5 4.3e-07 29.7 13.5 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 KRZ99090.1 - 6.3e-07 29.2 2.7 1.4e-06 28.1 2.7 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.6 KRZ99090.1 - 2e-06 27.7 15.4 4.2e-06 26.7 8.2 3.2 2 1 1 3 3 3 1 RING-type zinc-finger zf-RING_2 PF13639.6 KRZ99090.1 - 4.3e-06 26.9 18.2 7.5e-06 26.2 12.2 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 KRZ99090.1 - 1.1e-05 25.2 15.8 7.6e-05 22.6 11.7 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KRZ99090.1 - 1.2e-05 25.1 15.1 1.4e-05 24.9 9.5 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KRZ99090.1 - 1.6e-05 24.6 13.5 0.0001 22.1 10.0 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KRZ99090.1 - 2.5e-05 24.5 7.2 2.5e-05 24.5 7.2 2.5 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_10 PF16685.5 KRZ99090.1 - 2.8e-05 24.1 9.0 6.4e-05 23.0 9.0 1.6 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 KRZ99090.1 - 4.5e-05 23.5 12.5 4.5e-05 23.5 12.5 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING Zn-C2H2_12 PF18112.1 KRZ99090.1 - 0.013 16.0 1.0 2.5 8.6 0.1 2.9 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-Nse PF11789.8 KRZ99090.1 - 0.14 12.0 11.1 0.74 9.7 7.6 2.7 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Mob_synth_C PF06463.13 KRZ99090.1 - 0.24 11.3 3.6 0.24 11.4 1.0 2.3 2 0 0 2 2 2 0 Molybdenum Cofactor Synthesis C zf-ANAPC11 PF12861.7 KRZ99090.1 - 0.25 11.4 6.7 0.052 13.6 2.9 1.9 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Spore_coat_CotO PF14153.6 KRZ99090.1 - 0.35 10.8 5.1 2.6 7.9 0.8 2.2 2 0 0 2 2 2 0 Spore coat protein CotO DUF1272 PF06906.11 KRZ99090.1 - 0.4 10.8 9.2 0.15 12.2 6.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) zf-Di19 PF05605.12 KRZ99090.1 - 2.1 8.7 10.4 0.68 10.3 0.4 2.8 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Form_Nir_trans PF01226.17 KRZ99091.1 - 1.7e-55 187.9 22.2 2.5e-55 187.4 22.2 1.2 1 0 0 1 1 1 1 Formate/nitrite transporter DEAD PF00270.29 KRZ99092.1 - 7.6e-35 120.3 1.0 1.6e-34 119.2 1.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KRZ99092.1 - 1e-30 106.3 3.7 9.5e-29 100.0 0.1 2.7 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 KRZ99092.1 - 1.9e-07 31.2 4.7 3.3e-07 30.5 0.1 2.8 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DnaI_N PF07319.11 KRZ99092.1 - 0.012 16.3 2.1 0.63 10.7 0.4 3.3 2 1 0 2 2 2 0 Primosomal protein DnaI N-terminus Peptidase_C37 PF05416.12 KRZ99092.1 - 0.071 11.6 1.1 3.6 6.0 0.1 2.2 2 0 0 2 2 2 0 Southampton virus-type processing peptidase Flavi_DEAD PF07652.14 KRZ99092.1 - 0.15 12.0 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain MFS_1 PF07690.16 KRZ99093.1 - 6.9e-36 123.9 37.9 6.9e-36 123.9 37.9 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KRZ99093.1 - 1.8e-08 33.7 12.3 1.8e-08 33.7 12.3 3.1 2 2 0 3 3 3 1 Sugar (and other) transporter DUF4191 PF13829.6 KRZ99093.1 - 2.8 7.2 11.4 1.3 8.3 1.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4191) Aha1_N PF09229.11 KRZ99095.1 - 8.4e-12 45.5 0.4 1.1e-11 45.0 0.4 1.2 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal DUF150_C PF17384.2 KRZ99095.1 - 0.046 13.8 0.8 0.44 10.7 0.3 2.0 1 1 1 2 2 2 0 RimP C-terminal SH3 domain Ribosomal_L23 PF00276.20 KRZ99095.1 - 0.058 13.8 0.1 0.07 13.5 0.1 1.4 1 1 0 1 1 1 0 Ribosomal protein L23 YL1 PF05764.13 KRZ99096.1 - 3e-39 135.6 55.4 3e-39 135.6 55.4 4.5 2 2 0 2 2 2 1 YL1 nuclear protein YL1_C PF08265.11 KRZ99096.1 - 5.6e-10 38.8 0.1 9.6e-10 38.1 0.1 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Methyltransf_23 PF13489.6 KRZ99097.1 - 9.4e-18 64.6 0.0 1.4e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KRZ99097.1 - 4.9e-15 56.0 0.0 9e-15 55.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KRZ99097.1 - 8.3e-13 48.4 0.0 1.4e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KRZ99097.1 - 4.1e-12 46.6 0.0 8.2e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KRZ99097.1 - 4.2e-11 43.5 0.0 7.9e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KRZ99097.1 - 4.5e-05 22.9 0.0 6.1e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 KRZ99097.1 - 0.00012 21.7 0.0 0.00018 21.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 KRZ99097.1 - 0.00013 21.3 0.0 0.00017 21.0 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MetW PF07021.12 KRZ99097.1 - 0.00023 20.8 0.1 0.00071 19.2 0.0 1.8 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW PrmA PF06325.13 KRZ99097.1 - 0.00029 20.3 0.0 0.00041 19.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) NodS PF05401.11 KRZ99097.1 - 0.00096 18.8 0.0 0.0014 18.3 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_32 PF13679.6 KRZ99097.1 - 0.0024 17.9 0.0 0.0052 16.8 0.0 1.5 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 KRZ99097.1 - 0.014 15.4 0.0 0.027 14.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_9 PF08003.11 KRZ99097.1 - 0.021 13.7 0.0 0.038 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) TehB PF03848.14 KRZ99097.1 - 0.091 12.2 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB RrnaAD PF00398.20 KRZ99097.1 - 0.1 11.7 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PCMT PF01135.19 KRZ99097.1 - 0.13 12.0 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Snf7 PF03357.21 KRZ99098.1 - 5.4e-44 149.8 13.1 6.7e-44 149.5 13.1 1.0 1 0 0 1 1 1 1 Snf7 Seryl_tRNA_N PF02403.22 KRZ99098.1 - 0.0087 16.3 12.4 0.11 12.8 3.5 2.5 1 1 0 2 2 2 2 Seryl-tRNA synthetase N-terminal domain DUF1465 PF07323.12 KRZ99098.1 - 0.028 14.3 2.4 0.029 14.2 0.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1465) Ca_bind_SSO6904 PF18249.1 KRZ99098.1 - 0.066 13.6 0.4 0.25 11.7 0.1 2.0 1 1 1 2 2 2 0 Calcium binding protein SSO6904 DUF2120 PF09893.9 KRZ99098.1 - 0.11 12.6 3.0 0.11 12.6 1.7 1.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2120) FlaC_arch PF05377.11 KRZ99098.1 - 0.21 12.0 5.8 5.5 7.5 0.0 3.6 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) CLZ PF16526.5 KRZ99098.1 - 0.44 10.9 0.0 0.44 10.9 0.0 3.2 3 1 1 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Atg14 PF10186.9 KRZ99098.1 - 0.81 8.7 5.7 1.2 8.1 5.7 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FapA PF03961.13 KRZ99098.1 - 2.9 6.4 9.8 1.8 7.1 5.3 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A NPV_P10 PF05531.12 KRZ99098.1 - 5.6 7.5 13.7 17 5.9 0.1 3.6 2 1 2 4 4 4 0 Nucleopolyhedrovirus P10 protein Fapy_DNA_glyco PF01149.24 KRZ99099.1 - 1.7e-32 112.4 0.1 3.3e-32 111.5 0.1 1.5 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.14 KRZ99099.1 - 6.4e-13 48.5 0.0 1.2e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain Di19_C PF14571.6 KRZ99099.1 - 0.47 11.0 0.0 0.47 11.0 0.0 2.3 2 0 0 2 2 2 0 Stress-induced protein Di19, C-terminal HSP70 PF00012.20 KRZ99100.1 - 1.2e-261 869.2 9.9 1.3e-261 869.0 9.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KRZ99100.1 - 6.7e-16 58.0 0.2 1.2e-14 53.8 0.1 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 KRZ99100.1 - 0.003 17.3 0.0 0.007 16.1 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.10 KRZ99100.1 - 0.037 13.0 0.5 0.42 9.5 0.2 2.1 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain Cnd1_N PF12922.7 KRZ99100.1 - 0.16 11.8 1.7 0.34 10.7 1.7 1.5 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term PMBR PF09373.10 KRZ99100.1 - 0.58 10.4 0.1 0.58 10.4 0.1 2.8 3 0 0 3 3 3 0 Pseudomurein-binding repeat Na_Ca_ex PF01699.24 KRZ99101.1 - 1.7e-40 138.4 40.9 5.6e-25 88.1 16.7 2.5 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF3488 PF11992.8 KRZ99101.1 - 2.2 7.1 8.1 2.2 7.1 1.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3488) Abhydro_lipase PF04083.16 KRZ99102.1 - 8.3e-15 54.1 0.2 1.5e-14 53.3 0.2 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 KRZ99102.1 - 4.3e-13 49.5 0.1 6.2e-13 49.0 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold FSH1 PF03959.13 KRZ99102.1 - 1.3e-06 28.2 0.0 0.026 14.2 0.0 2.3 1 1 0 2 2 2 2 Serine hydrolase (FSH1) Hydrolase_4 PF12146.8 KRZ99102.1 - 0.0019 17.5 0.0 0.12 11.6 0.0 2.3 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DUF3336 PF11815.8 KRZ99102.1 - 0.015 15.0 0.0 0.026 14.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3336) Swm2 PF17083.5 KRZ99103.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Nucleolar protein Swm2 MBOAT PF03062.19 KRZ99104.1 - 2.9e-66 224.2 21.4 4.8e-66 223.5 21.4 1.3 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Mitochondr_Som1 PF11093.8 KRZ99105.1 - 3.7e-25 87.7 0.2 5.2e-25 87.3 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial export protein Som1 Propep_M14 PF02244.16 KRZ99105.1 - 0.0076 16.6 0.1 0.037 14.4 0.0 1.9 2 0 0 2 2 2 1 Carboxypeptidase activation peptide UQ_con PF00179.26 KRZ99106.1 - 1.4e-20 73.3 0.0 1.6e-20 73.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KRZ99106.1 - 0.0083 16.4 0.0 0.0091 16.3 0.0 1.2 1 0 0 1 1 1 1 RWD domain MAD PF05557.13 KRZ99107.1 - 9.6e-28 96.9 79.5 1.4e-27 96.4 79.5 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein BLOC1_2 PF10046.9 KRZ99107.1 - 0.0034 17.7 4.7 0.0034 17.7 4.7 8.4 4 2 4 8 8 8 4 Biogenesis of lysosome-related organelles complex-1 subunit 2 HALZ PF02183.18 KRZ99107.1 - 0.026 14.7 0.5 0.026 14.7 0.5 10.9 8 4 2 12 12 12 0 Homeobox associated leucine zipper PRP1_N PF06424.12 KRZ99108.1 - 1.4e-38 132.6 3.3 3.8e-38 131.2 3.3 1.8 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 KRZ99108.1 - 2.4e-16 59.0 0.0 1.3 10.0 0.0 10.9 7 4 5 12 12 12 4 Tetratricopeptide repeat TPR_19 PF14559.6 KRZ99108.1 - 4.4e-08 33.5 0.0 1 9.9 0.0 7.4 7 2 0 7 7 7 1 Tetratricopeptide repeat TPR_17 PF13431.6 KRZ99108.1 - 4.7e-06 26.6 13.2 19 5.9 0.0 9.7 11 0 0 11 11 10 0 Tetratricopeptide repeat TPR_2 PF07719.17 KRZ99108.1 - 0.00039 20.3 1.3 53 4.3 0.0 6.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.28 KRZ99108.1 - 0.0012 18.6 0.2 7.7 6.5 0.0 4.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 KRZ99108.1 - 0.003 17.6 4.2 44 4.7 0.0 6.2 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF536 PF04394.14 KRZ99108.1 - 0.045 13.6 4.1 0.48 10.3 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function, DUF536 HGAL PF15666.5 KRZ99108.1 - 0.31 11.2 1.5 0.9 9.7 1.3 1.9 1 1 0 1 1 1 0 Germinal center-associated lymphoma DUF2732 PF10809.8 KRZ99108.1 - 0.73 9.7 5.4 1.9 8.4 0.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2732) CDC27 PF09507.10 KRZ99108.1 - 0.99 8.7 9.9 1.8 7.9 9.9 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CAF1C_H4-bd PF12265.8 KRZ99109.1 - 1.7e-15 57.0 0.0 3.9e-15 55.8 0.0 1.7 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 KRZ99109.1 - 1.1e-09 38.7 13.7 0.0015 19.3 0.1 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KRZ99109.1 - 2.3e-06 27.8 0.5 0.067 13.5 0.2 3.4 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain DUF3246 PF11596.8 KRZ99109.1 - 9.7 5.5 12.4 0.12 11.8 4.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) Kelch_4 PF13418.6 KRZ99110.1 - 8.9e-34 115.3 4.7 7.3e-08 32.3 0.0 5.6 4 2 1 5 5 5 5 Galactose oxidase, central domain Kelch_3 PF13415.6 KRZ99110.1 - 1.9e-31 107.7 0.3 2e-12 47.1 0.0 5.4 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.6 KRZ99110.1 - 5.3e-19 67.8 6.1 0.00013 22.2 0.1 5.2 5 0 0 5 5 5 5 Kelch motif Kelch_5 PF13854.6 KRZ99110.1 - 6.8e-17 61.1 4.4 0.001 19.0 0.1 5.4 5 1 0 5 5 5 4 Kelch motif Kelch_2 PF07646.15 KRZ99110.1 - 4.9e-08 32.6 16.0 0.0047 16.8 0.3 6.0 5 2 0 5 5 5 3 Kelch motif Kelch_1 PF01344.25 KRZ99110.1 - 8.1e-08 31.7 9.1 0.0017 17.9 0.1 4.1 4 1 0 4 4 4 3 Kelch motif RB_B PF01857.20 KRZ99110.1 - 0.021 14.8 1.1 0.1 12.6 0.0 2.4 3 0 0 3 3 3 0 Retinoblastoma-associated protein B domain Imm-NTF2 PF15655.6 KRZ99110.1 - 0.12 12.6 7.1 1.7 8.9 0.7 2.8 2 0 0 2 2 2 0 NTF2 fold immunity protein VIT1 PF01988.19 KRZ99110.1 - 9.7 6.0 10.7 0.22 11.3 0.9 2.2 2 0 0 2 2 2 0 VIT family ACOX PF01756.19 KRZ99111.1 - 8.2e-43 146.0 0.3 1.7e-42 145.0 0.3 1.5 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 KRZ99111.1 - 6.3e-23 80.8 0.1 1.4e-22 79.7 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.6 KRZ99111.1 - 2e-13 51.0 0.1 5.1e-13 49.7 0.0 1.8 2 0 0 2 2 2 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.24 KRZ99111.1 - 0.00016 21.9 0.1 0.042 14.1 0.0 2.5 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain ACOX PF01756.19 KRZ99112.1 - 2.2e-42 144.6 0.0 4.1e-42 143.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 KRZ99112.1 - 1.7e-22 79.4 0.0 3.1e-22 78.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.6 KRZ99112.1 - 4.5e-17 62.8 0.3 1e-16 61.6 0.3 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.24 KRZ99112.1 - 8.1e-08 32.6 0.5 3.3e-06 27.4 0.0 2.4 1 1 1 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain LemA PF04011.12 KRZ99112.1 - 0.058 13.3 2.7 0.58 10.0 0.7 2.3 2 0 0 2 2 2 0 LemA family T3SS_basalb_I PF17001.5 KRZ99112.1 - 0.25 12.0 2.0 10 6.8 0.1 3.0 2 1 1 3 3 3 0 Type III secretion basal body protein I, YscI, HrpB, PscI LRR_6 PF13516.6 KRZ99113.1 - 0.00028 20.7 13.0 7.1 7.0 0.1 7.4 8 0 0 8 8 8 2 Leucine Rich repeat LRR_8 PF13855.6 KRZ99113.1 - 0.0039 16.9 17.2 0.85 9.4 3.0 4.7 4 2 0 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 KRZ99113.1 - 0.0046 17.3 23.1 0.084 13.3 2.8 6.1 5 2 2 7 7 7 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KRZ99113.1 - 0.044 14.3 9.0 1.2e+02 3.8 1.9 6.6 7 1 0 7 7 7 0 Leucine Rich Repeat DUF4763 PF15960.5 KRZ99113.1 - 0.046 13.0 7.0 0.096 12.0 7.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) CobT PF06213.12 KRZ99113.1 - 0.05 13.0 7.4 0.077 12.4 7.4 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Sec63 PF02889.16 KRZ99113.1 - 0.057 12.6 0.1 0.11 11.7 0.1 1.4 1 0 0 1 1 1 0 Sec63 Brl domain DUF4486 PF14858.6 KRZ99113.1 - 0.19 10.2 0.8 0.29 9.6 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4486) AAA_23 PF13476.6 KRZ99114.1 - 1.2e-34 120.6 0.3 1.2e-34 120.6 0.3 8.2 1 1 3 4 4 2 1 AAA domain AAA_21 PF13304.6 KRZ99114.1 - 2.9e-07 30.6 3.3 0.00012 22.0 0.7 5.2 3 2 0 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KRZ99114.1 - 3.1e-07 30.1 0.1 3.1e-07 30.1 0.1 3.6 2 1 0 2 2 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 KRZ99114.1 - 2.9e-05 24.2 0.0 7.5e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit DUF4349 PF14257.6 KRZ99114.1 - 0.00015 21.3 1.3 0.00015 21.3 1.3 5.8 7 2 1 8 8 8 1 Domain of unknown function (DUF4349) AAA_16 PF13191.6 KRZ99114.1 - 0.0053 17.2 0.0 0.17 12.3 0.0 3.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 KRZ99114.1 - 0.0066 16.2 0.0 0.027 14.2 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain FCD PF07729.12 KRZ99114.1 - 0.0068 16.8 0.8 50 4.3 0.0 4.4 4 0 0 4 4 4 0 FCD domain AAA_15 PF13175.6 KRZ99114.1 - 0.031 14.0 144.2 0.019 14.7 38.8 5.9 1 1 3 4 4 2 0 AAA ATPase domain AAA_13 PF13166.6 KRZ99114.1 - 0.11 11.1 135.7 0.03 13.0 42.4 7.5 3 1 4 7 7 6 0 AAA domain AAA_22 PF13401.6 KRZ99114.1 - 0.19 12.0 0.1 0.19 12.0 0.1 4.2 4 0 0 4 4 3 0 AAA domain DUF1192 PF06698.11 KRZ99114.1 - 0.59 10.2 12.2 25 5.0 1.2 5.5 4 1 1 5 5 5 0 Protein of unknown function (DUF1192) LEM PF03020.15 KRZ99114.1 - 4.5 6.9 5.6 50 3.6 0.1 3.7 3 0 0 3 3 3 0 LEM domain Plasmid_RAQPRD PF09686.10 KRZ99114.1 - 8.3 6.7 7.6 3.9 7.8 0.8 4.3 4 0 0 4 4 3 0 Plasmid protein of unknown function (Plasmid_RAQPRD) Acyltransf_C PF16076.5 KRZ99115.1 - 8.2e-09 35.4 0.1 2.3e-08 34.0 0.1 1.8 1 0 0 1 1 1 1 Acyltransferase C-terminus RRM_1 PF00076.22 KRZ99116.1 - 7.1e-74 243.6 10.5 2.8e-16 59.1 0.1 5.5 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KRZ99116.1 - 5e-12 45.5 0.1 0.0058 16.2 0.0 4.6 3 1 1 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KRZ99116.1 - 5.5e-05 23.1 2.8 1.1 9.3 0.1 5.2 6 0 0 6 6 6 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 KRZ99116.1 - 0.00081 19.2 0.0 0.41 10.5 0.0 4.0 4 0 0 4 4 4 1 Occluded RNA-recognition motif RRM_7 PF16367.5 KRZ99116.1 - 0.0041 17.2 0.5 6.6 6.9 0.0 4.4 5 0 0 5 5 5 1 RNA recognition motif Limkain-b1 PF11608.8 KRZ99116.1 - 0.021 14.9 0.1 15 5.8 0.0 4.4 4 0 0 4 4 4 0 Limkain b1 DUF2981 PF11200.8 KRZ99116.1 - 7.8 6.1 8.0 4.6 6.9 4.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2981) Rhomboid PF01694.22 KRZ99117.1 - 1.1e-25 90.4 14.0 1.1e-25 90.4 14.0 1.5 2 0 0 2 2 2 1 Rhomboid family Tox-ODYAM1 PF15642.6 KRZ99118.1 - 0.12 11.3 8.2 0.16 10.9 8.2 1.2 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus Na_trans_assoc PF06512.13 KRZ99119.1 - 0.64 10.3 10.5 0.77 10.0 10.5 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated IBN_N PF03810.19 KRZ99120.1 - 1.5e-13 50.5 0.0 6.3e-13 48.4 0.0 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain PBP1_TM PF14812.6 KRZ99120.1 - 6.8 7.1 6.9 1.1 9.6 1.1 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SurE PF01975.17 KRZ99121.1 - 2.1e-10 40.7 0.0 1.7e-05 24.7 0.0 2.6 2 1 0 2 2 2 2 Survival protein SurE AA_permease_2 PF13520.6 KRZ99122.1 - 4.2e-60 203.8 30.4 5.6e-60 203.3 30.4 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KRZ99122.1 - 7.2e-11 41.4 25.8 7.2e-11 41.4 25.8 2.0 2 0 0 2 2 2 1 Amino acid permease Pex26 PF07163.12 KRZ99123.1 - 0.0058 16.0 2.3 0.01 15.2 2.3 1.4 1 0 0 1 1 1 1 Pex26 protein Sec62 PF03839.16 KRZ99123.1 - 0.14 11.6 6.1 0.27 10.7 6.1 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 EMC3_TMCO1 PF01956.16 KRZ99123.1 - 0.44 10.3 6.2 0.12 12.1 2.7 1.8 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like EIIBC-GUT_N PF03612.14 KRZ99123.1 - 4 7.2 6.0 6.6 6.4 6.0 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Rad1 PF02144.16 KRZ99124.1 - 8.8e-58 195.5 6.1 1.1e-57 195.2 6.1 1.1 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 AP_endonuc_2_N PF07582.12 KRZ99124.1 - 0.16 11.7 0.0 0.4 10.4 0.0 1.6 1 0 0 1 1 1 0 AP endonuclease family 2 C terminus vATP-synt_AC39 PF01992.16 KRZ99125.1 - 5e-104 348.4 0.7 5.6e-104 348.3 0.7 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Dor1 PF04124.12 KRZ99126.1 - 2.3e-18 66.0 19.0 8.3e-18 64.2 19.0 1.9 1 1 0 1 1 1 1 Dor1-like family DUF1664 PF07889.12 KRZ99126.1 - 0.14 12.2 1.6 0.36 10.9 1.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) SNF2_N PF00176.23 KRZ99127.1 - 9.7e-62 208.7 0.0 1.7e-61 207.9 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KRZ99127.1 - 5.4e-21 75.0 0.0 1.1e-19 70.9 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KRZ99127.1 - 1.1e-06 28.8 0.4 3.6e-06 27.1 0.0 2.2 2 0 0 2 2 1 1 Type III restriction enzyme, res subunit zf-C3HC4_3 PF13920.6 KRZ99127.1 - 9.5e-06 25.4 1.4 2.3e-05 24.2 1.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KRZ99127.1 - 1.8e-05 24.7 4.5 5.2e-05 23.2 4.5 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KRZ99127.1 - 0.00012 21.8 1.4 0.00045 20.0 1.4 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KRZ99127.1 - 0.0002 21.6 6.3 0.0002 21.6 3.6 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 KRZ99127.1 - 0.00064 19.6 3.7 0.0017 18.3 3.7 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KRZ99127.1 - 0.0019 18.0 4.2 0.0029 17.4 2.1 2.5 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 KRZ99127.1 - 0.0048 16.7 1.8 0.012 15.4 1.8 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein Baculo_IE-1 PF05290.11 KRZ99127.1 - 0.11 12.4 0.6 0.3 11.0 0.6 1.7 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) FYVE PF01363.21 KRZ99127.1 - 0.24 11.6 1.1 0.58 10.3 1.1 1.7 1 0 0 1 1 1 0 FYVE zinc finger TMPIT PF07851.13 KRZ99127.1 - 0.42 9.8 2.4 0.81 8.9 2.4 1.4 1 0 0 1 1 1 0 TMPIT-like protein zf-C3HC4_5 PF17121.5 KRZ99127.1 - 0.7 9.8 3.1 2 8.4 3.1 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KRZ99127.1 - 1.3 8.9 9.1 60 3.6 9.9 2.7 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 CENP-Q PF13094.6 KRZ99127.1 - 2.5 8.3 12.3 0.32 11.2 7.1 2.3 2 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit zf-C3HC4_4 PF15227.6 KRZ99127.1 - 7.5 6.8 12.0 0.61 10.3 6.3 2.3 2 1 0 2 2 1 0 zinc finger of C3HC4-type, RING TPR_2 PF07719.17 KRZ99128.1 - 1.2e-07 31.3 4.1 0.00025 20.9 0.5 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KRZ99128.1 - 2.7e-06 26.9 5.5 7.5e-05 22.4 0.7 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 KRZ99128.1 - 0.00038 20.1 0.9 0.0026 17.4 0.2 2.4 2 0 0 2 2 2 1 TPR repeat TPR_9 PF13371.6 KRZ99128.1 - 0.00083 19.5 0.1 0.0025 17.9 0.0 1.8 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KRZ99128.1 - 0.0042 17.2 0.4 0.12 12.7 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KRZ99128.1 - 0.012 16.3 2.2 9.8 6.9 0.6 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat MotY_N PF18393.1 KRZ99128.1 - 0.13 12.3 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 MotY N-terminal domain TPR_12 PF13424.6 KRZ99128.1 - 0.17 12.2 1.3 0.76 10.1 0.1 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Fungal_trans PF04082.18 KRZ99129.1 - 3.3e-20 72.2 0.8 5.4e-20 71.5 0.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain NOB1_Zn_bind PF08772.11 KRZ99129.1 - 0.099 12.8 1.4 0.58 10.4 0.0 2.4 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Lyase_1 PF00206.20 KRZ99130.1 - 1.3e-49 169.3 0.0 1.9e-49 168.8 0.0 1.1 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 KRZ99130.1 - 4.8e-16 59.1 0.0 3e-15 56.5 0.0 2.2 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus Sugar_tr PF00083.24 KRZ99131.1 - 7.2e-100 335.0 24.4 9.3e-100 334.6 24.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KRZ99131.1 - 1.3e-27 96.7 52.5 4.6e-25 88.3 25.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KRZ99131.1 - 7e-05 21.4 0.3 7e-05 21.4 0.3 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF2530 PF10745.9 KRZ99131.1 - 0.075 13.3 0.1 0.075 13.3 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2530) DUF4233 PF14017.6 KRZ99131.1 - 3.8 7.9 10.5 0.6 10.5 1.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4233) DUF2264 PF10022.9 KRZ99132.1 - 1.1e-121 406.3 0.0 1.4e-121 405.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) Glyco_hydro_18 PF00704.28 KRZ99133.1 - 4.9e-25 88.9 3.5 8.3e-25 88.2 1.2 2.3 2 1 0 2 2 2 1 Glycosyl hydrolases family 18 Flocculin_t3 PF13928.6 KRZ99133.1 - 8.3e-22 77.4 44.9 9.9e-13 48.4 18.8 4.5 4 1 0 4 4 4 2 Flocculin type 3 repeat DUF1397 PF07165.11 KRZ99133.1 - 0.032 13.6 0.1 0.079 12.4 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1397) Aldose_epim PF01263.20 KRZ99134.1 - 1.2e-49 169.2 0.3 1.7e-49 168.8 0.3 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase DJ-1_PfpI PF01965.24 KRZ99135.1 - 4.3e-07 29.9 0.0 6.1e-06 26.1 0.0 2.1 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 KRZ99135.1 - 7e-05 22.6 0.0 0.002 17.9 0.0 2.1 1 1 0 1 1 1 1 ThiJ/PfpI family-like Mannosyl_trans3 PF11051.8 KRZ99136.1 - 1.3e-79 267.4 0.1 2.3e-79 266.6 0.1 1.4 1 0 0 1 1 1 1 Mannosyltransferase putative MFS_1 PF07690.16 KRZ99137.1 - 9.2e-05 21.5 7.8 0.00021 20.3 6.7 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily O-antigen_lig PF13425.6 KRZ99137.1 - 0.15 10.8 3.8 0.18 10.5 3.3 1.4 1 1 0 1 1 1 0 O-antigen ligase like membrane protein DUF412 PF04217.13 KRZ99137.1 - 0.5 10.3 3.3 0.7 9.8 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF412 YibE_F PF07907.11 KRZ99137.1 - 1.5 8.3 9.2 2 7.8 0.5 2.1 2 0 0 2 2 2 0 YibE/F-like protein DAG_kinase_N PF14513.6 KRZ99138.1 - 0.052 13.8 8.3 0.087 13.0 8.3 1.2 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus RNA_pol_Rpc4 PF05132.14 KRZ99138.1 - 0.12 12.8 5.5 0.3 11.5 5.5 1.7 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF4746 PF15928.5 KRZ99138.1 - 0.16 11.4 9.7 0.24 10.8 9.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) NPR3 PF03666.13 KRZ99138.1 - 0.38 9.5 12.8 0.54 9.0 12.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 PIEZO PF15917.5 KRZ99138.1 - 0.74 9.2 15.0 1.1 8.6 15.0 1.2 1 0 0 1 1 1 0 Piezo AAA_21 PF13304.6 KRZ99138.1 - 1.7 8.4 5.6 2.7 7.7 5.6 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system RR_TM4-6 PF06459.12 KRZ99138.1 - 3.6 7.3 18.1 5.4 6.8 18.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 KRZ99138.1 - 4.1 6.1 13.0 5.8 5.6 13.0 1.1 1 0 0 1 1 1 0 Presenilin DUF1216 PF06746.11 KRZ99139.1 - 0.0095 16.0 0.2 0.052 13.6 0.2 2.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1216) zf-ribbon_3 PF13248.6 KRZ99139.1 - 0.6 9.6 5.9 0.075 12.5 0.7 2.1 2 0 0 2 2 2 0 zinc-ribbon domain DEAD PF00270.29 KRZ99140.1 - 4e-12 46.2 0.0 1.1e-11 44.9 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KRZ99140.1 - 2e-10 41.0 0.1 1.7e-09 38.0 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KRZ99140.1 - 0.00013 22.0 0.0 0.00036 20.6 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Lum_binding PF00677.17 KRZ99141.1 - 1.8e-43 146.4 3.9 1.5e-21 76.1 0.7 2.3 2 0 0 2 2 2 2 Lumazine binding domain Spore_GerAC PF05504.11 KRZ99141.1 - 0.058 13.6 3.7 0.074 13.3 2.9 1.6 1 1 0 1 1 1 0 Spore germination B3/ GerAC like, C-terminal Proteasome PF00227.26 KRZ99142.1 - 1.3e-38 132.4 0.0 1.5e-38 132.2 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Exonuc_VII_S PF02609.16 KRZ99142.1 - 0.096 12.8 1.4 0.19 11.8 1.4 1.5 1 0 0 1 1 1 0 Exonuclease VII small subunit Herpes_UL3 PF03369.13 KRZ99142.1 - 0.12 12.9 0.1 0.22 12.1 0.1 1.5 1 1 0 1 1 1 0 Herpesvirus UL3 protein HA2 PF04408.23 KRZ99143.1 - 3.1e-25 88.6 0.0 3.1e-25 88.6 0.0 3.0 3 0 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KRZ99143.1 - 1.6e-21 76.5 0.2 4.5e-21 75.0 0.0 1.9 2 0 0 2 2 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KRZ99143.1 - 2.6e-13 50.3 0.0 9.7e-13 48.4 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.23 KRZ99143.1 - 4.3e-12 46.2 0.0 1.5e-11 44.5 0.0 1.9 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.29 KRZ99143.1 - 4.6e-06 26.5 0.1 9.6e-06 25.5 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KRZ99143.1 - 6.6e-06 26.4 0.0 3.4e-05 24.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KRZ99143.1 - 0.0018 18.7 0.1 0.0043 17.4 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KRZ99143.1 - 0.0019 18.2 0.3 0.13 12.3 0.3 2.9 1 1 0 1 1 1 1 AAA domain SRP54 PF00448.22 KRZ99143.1 - 0.004 16.8 0.1 0.0082 15.8 0.1 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain T2SSE PF00437.20 KRZ99143.1 - 0.032 13.3 0.0 0.079 12.0 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.6 KRZ99143.1 - 0.034 13.9 0.0 0.063 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KRZ99143.1 - 0.4 11.2 15.2 0.12 12.9 0.3 4.3 4 1 0 4 4 4 0 ABC transporter Cellulase PF00150.18 KRZ99144.1 - 1.3e-14 54.3 0.8 1e-07 31.7 0.2 2.8 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_5_C PF18564.1 KRZ99144.1 - 2.6e-13 50.3 0.1 5.8e-13 49.2 0.1 1.6 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Diphtheria_R PF01324.19 KRZ99144.1 - 0.034 13.8 0.0 0.078 12.6 0.0 1.5 1 0 0 1 1 1 0 Diphtheria toxin, R domain DNA_primase_S PF01896.19 KRZ99145.1 - 9.6e-70 234.2 0.8 1.6e-69 233.5 0.8 1.4 1 0 0 1 1 1 1 DNA primase small subunit ATP-synt_Eps PF04627.13 KRZ99145.1 - 0.061 13.3 1.0 60 3.7 0.0 3.7 4 0 0 4 4 4 0 Mitochondrial ATP synthase epsilon chain ANAPC4_WD40 PF12894.7 KRZ99146.1 - 3e-06 27.4 0.7 0.021 15.1 0.1 4.3 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KRZ99146.1 - 3.3e-05 24.5 5.6 4.4 8.3 0.0 6.5 6 1 0 6 6 6 2 WD domain, G-beta repeat DUF5046 PF16465.5 KRZ99146.1 - 0.049 13.1 0.0 0.092 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5046) PQQ_3 PF13570.6 KRZ99146.1 - 0.089 13.3 1.9 7.6 7.2 0.0 4.0 3 1 1 4 4 4 0 PQQ-like domain Prenyltransf PF01255.19 KRZ99147.1 - 6.5e-74 248.2 0.0 8.1e-74 247.9 0.0 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase HisG PF01634.18 KRZ99148.1 - 6.3e-39 133.5 0.2 1.1e-38 132.8 0.2 1.3 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 KRZ99148.1 - 4.4e-29 100.4 0.0 7.9e-29 99.6 0.0 1.4 1 0 0 1 1 1 1 HisG, C-terminal domain YceG PF02618.16 KRZ99148.1 - 0.0067 16.0 0.2 0.0077 15.8 0.2 1.2 1 0 0 1 1 1 1 YceG-like family APAF1_C PF17908.1 KRZ99148.1 - 0.13 12.3 0.0 0.32 11.0 0.0 1.7 1 0 0 1 1 1 0 APAF-1 helical domain Aminotran_5 PF00266.19 KRZ99149.1 - 8.2e-18 64.5 0.0 1e-17 64.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 KRZ99149.1 - 7.8e-05 21.4 0.0 0.00011 20.9 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme SepSecS PF05889.13 KRZ99149.1 - 0.00073 18.3 0.0 0.00087 18.1 0.0 1.1 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Aminotran_1_2 PF00155.21 KRZ99149.1 - 0.0045 16.2 0.0 0.0059 15.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KRZ99149.1 - 0.052 12.9 0.0 0.24 10.6 0.0 1.8 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family RPN5_C PF18098.1 KRZ99150.1 - 2.5e-16 59.5 2.7 4.6e-16 58.6 0.6 2.7 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN5 C-terminal domain PCI PF01399.27 KRZ99150.1 - 2.8e-16 59.9 1.9 2.8e-16 59.9 1.9 2.7 2 1 0 2 2 2 1 PCI domain RPN6_N PF18055.1 KRZ99150.1 - 0.014 15.7 5.8 0.014 15.7 5.8 3.0 3 1 0 3 3 3 0 26S proteasome regulatory subunit RPN6 N-terminal domain VF530 PF09905.9 KRZ99150.1 - 0.13 12.5 1.4 0.71 10.1 0.1 2.9 3 0 0 3 3 3 0 DNA-binding protein VF530 RTP1_C1 PF10363.9 KRZ99150.1 - 0.17 12.1 5.0 0.093 12.9 1.5 2.3 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 Glyco_hydro_72 PF03198.14 KRZ99151.1 - 5.4e-141 469.4 7.6 7.3e-141 469.0 7.6 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 KRZ99151.1 - 4e-06 26.5 0.4 3.5e-05 23.4 0.4 2.3 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.17 KRZ99151.1 - 0.0058 15.8 1.2 0.018 14.1 1.2 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Serglycin PF04360.12 KRZ99151.1 - 0.35 10.8 11.0 1.1 9.2 11.0 1.9 1 0 0 1 1 1 0 Serglycin SR-25 PF10500.9 KRZ99151.1 - 4.9 6.7 19.2 9.4 5.8 19.2 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein F-box-like PF12937.7 KRZ99152.1 - 0.0012 18.7 0.0 0.0028 17.5 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KRZ99152.1 - 0.0088 15.9 0.1 0.069 13.0 0.0 2.5 2 0 0 2 2 2 1 F-box F-box PF00646.33 KRZ99152.1 - 0.0094 15.8 0.1 0.027 14.3 0.1 1.8 1 0 0 1 1 1 1 F-box domain COX7a PF02238.15 KRZ99153.1 - 6.9e-22 77.6 0.4 7.6e-22 77.5 0.4 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VII CcdA PF07362.12 KRZ99154.1 - 0.041 14.3 0.5 0.091 13.2 0.5 1.6 1 0 0 1 1 1 0 Post-segregation antitoxin CcdA BssC_TutF PF08201.11 KRZ99154.1 - 0.51 10.4 3.4 0.57 10.2 1.4 2.2 2 0 0 2 2 2 0 BssC/TutF protein zinc_ribbon_5 PF13719.6 KRZ99154.1 - 3.2 7.6 5.1 4 7.3 0.1 2.8 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_4 PF13717.6 KRZ99154.1 - 4.7 7.2 5.5 3.5 7.6 0.0 2.9 3 0 0 3 3 3 0 zinc-ribbon domain EAL PF00563.20 KRZ99155.1 - 0.13 11.8 0.0 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 EAL domain Kri1_C PF12936.7 KRZ99157.1 - 1.6e-32 111.5 3.2 1.6e-32 111.5 3.2 5.2 4 1 1 5 5 5 1 KRI1-like family C-terminal Kri1 PF05178.12 KRZ99157.1 - 2.6e-19 69.7 18.3 2.6e-19 69.7 18.3 5.7 5 1 0 6 6 6 1 KRI1-like family SHNi-TPR PF10516.9 KRZ99157.1 - 0.045 13.2 1.3 0.12 11.8 1.3 1.8 1 0 0 1 1 1 0 SHNi-TPR Sulfatase PF00884.23 KRZ99158.1 - 9.1e-74 248.6 0.0 1.8e-73 247.7 0.0 1.5 1 1 0 1 1 1 1 Sulfatase DUF229 PF02995.17 KRZ99158.1 - 2.4e-05 23.1 0.1 6.7e-05 21.7 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF229) Sulfatase_C PF14707.6 KRZ99158.1 - 0.00016 22.4 0.1 0.007 17.1 0.1 2.5 1 1 0 1 1 1 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.22 KRZ99158.1 - 0.0022 17.7 0.6 0.28 10.7 0.0 2.4 2 1 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase CorA PF01544.18 KRZ99159.1 - 4.9e-38 131.1 0.2 7e-23 81.4 0.0 2.2 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein DUF5333 PF17267.2 KRZ99159.1 - 0.16 12.2 0.1 0.39 10.9 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5333) Coprogen_oxidas PF01218.18 KRZ99160.1 - 5.2e-136 452.2 0.1 5.9e-136 452.0 0.1 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase VirArc_Nuclease PF12187.8 KRZ99160.1 - 0.22 11.0 1.1 0.37 10.3 1.1 1.2 1 0 0 1 1 1 0 Viral/Archaeal nuclease ABC2_membrane PF01061.24 KRZ99161.1 - 5.5e-41 140.3 21.7 5.5e-41 140.3 21.7 2.0 2 0 0 2 2 2 1 ABC-2 type transporter PDR_CDR PF06422.12 KRZ99161.1 - 0.00091 19.1 0.4 0.00091 19.1 0.4 2.7 4 0 0 4 4 4 1 CDR ABC transporter DUF2976 PF11190.8 KRZ99161.1 - 0.014 15.2 0.1 0.23 11.3 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) DUF3402 PF11882.8 KRZ99162.1 - 5.2e-92 309.4 28.2 1.1e-47 163.2 5.8 2.3 1 1 0 2 2 2 2 Domain of unknown function (DUF3402) N1221 PF07923.13 KRZ99162.1 - 2.5e-55 187.7 3.0 2.5e-55 187.7 3.0 2.1 2 1 1 3 3 3 1 N1221-like protein Tom22 PF04281.13 KRZ99163.1 - 3.1e-50 169.6 1.7 3.6e-50 169.4 1.7 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 CDP-OH_P_transf PF01066.21 KRZ99164.1 - 1.8e-16 60.7 0.1 1.8e-16 60.7 0.1 3.1 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Band_7 PF01145.25 KRZ99165.1 - 2.1e-29 102.8 3.8 3.1e-29 102.2 3.8 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 KRZ99165.1 - 0.0032 17.2 0.3 0.0047 16.7 0.3 1.3 1 0 0 1 1 1 1 SPFH domain-Band 7 family Latrotoxin_C PF15658.6 KRZ99165.1 - 0.15 11.8 1.0 0.2 11.4 0.2 1.6 2 0 0 2 2 2 0 Latrotoxin C-terminal domain DUF2040 PF09745.9 KRZ99166.1 - 0.0074 16.3 14.1 0.0074 16.3 14.1 2.7 1 1 0 2 2 2 1 Coiled-coil domain-containing protein 55 (DUF2040) PP2C_C PF07830.13 KRZ99166.1 - 1.7 9.2 11.3 0.19 12.2 0.7 2.7 3 0 0 3 3 3 0 Protein serine/threonine phosphatase 2C, C-terminal domain Glu-tRNAGln PF02686.15 KRZ99167.1 - 0.00051 20.3 0.6 0.0027 18.0 0.0 2.4 3 0 0 3 3 3 1 Glu-tRNAGln amidotransferase C subunit Pkinase PF00069.25 KRZ99168.1 - 8.2e-50 169.6 2.1 2.2e-49 168.2 0.0 2.5 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KRZ99168.1 - 5.2e-21 75.1 0.0 3.9e-20 72.2 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KRZ99168.1 - 0.012 14.9 0.6 0.45 9.8 0.3 2.9 2 1 0 2 2 2 0 Kinase-like GFD1 PF17331.2 KRZ99168.1 - 0.04 14.1 4.2 0.1 12.8 4.2 1.7 1 0 0 1 1 1 0 GFD1 mRNA transport factor RIO1 PF01163.22 KRZ99168.1 - 0.047 13.3 0.3 0.12 12.0 0.3 1.6 1 0 0 1 1 1 0 RIO1 family FTA2 PF13095.6 KRZ99168.1 - 0.047 13.3 1.4 11 5.6 0.0 2.9 2 1 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Actin PF00022.19 KRZ99169.1 - 5.9e-100 334.7 0.0 3.5e-99 332.2 0.0 1.8 1 1 0 1 1 1 1 Actin Actin_micro PF17003.5 KRZ99169.1 - 0.0036 16.6 0.9 0.029 13.6 0.2 2.1 2 0 0 2 2 2 1 Putative actin-like family MreB_Mbl PF06723.13 KRZ99169.1 - 0.006 15.5 0.0 0.027 13.3 0.0 2.0 1 1 0 1 1 1 1 MreB/Mbl protein GCD14 PF08704.10 KRZ99170.1 - 1e-84 284.1 0.0 1.4e-84 283.7 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 KRZ99170.1 - 0.0001 22.2 0.0 0.00021 21.1 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GCD14_N PF14801.6 KRZ99170.1 - 0.0062 16.4 0.0 0.017 15.0 0.0 1.7 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit N-term PepSY_2 PF13670.6 KRZ99170.1 - 0.043 13.8 0.2 0.092 12.8 0.2 1.5 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain Alpha_Helical PF18489.1 KRZ99170.1 - 0.087 13.0 0.1 2.5 8.3 0.0 2.2 2 0 0 2 2 2 0 Alpha helical domain Ubie_methyltran PF01209.18 KRZ99170.1 - 0.1 11.9 0.0 1 8.6 0.0 2.0 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KRZ99170.1 - 0.15 11.8 0.0 0.27 11.0 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain LSM PF01423.22 KRZ99171.1 - 2.5e-14 52.7 0.1 4.7e-14 51.8 0.1 1.4 1 0 0 1 1 1 1 LSM domain UvrD-helicase PF00580.21 KRZ99171.1 - 0.037 13.6 0.2 0.049 13.1 0.2 1.1 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Acyl-CoA_dh_1 PF00441.24 KRZ99172.1 - 4.4e-26 91.9 0.4 6.3e-26 91.4 0.4 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KRZ99172.1 - 2.1e-12 47.1 0.0 3.9e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KRZ99172.1 - 2.3e-12 47.5 0.0 4.2e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KRZ99172.1 - 3.7e-07 30.5 0.0 5.5e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain RPN7 PF10602.9 KRZ99173.1 - 1.1e-55 188.1 2.3 2.1e-55 187.1 2.3 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 KRZ99173.1 - 1.3e-15 57.8 2.2 8.3e-15 55.2 0.5 2.4 2 0 0 2 2 2 1 PCI domain TPR_12 PF13424.6 KRZ99173.1 - 0.00017 21.8 0.8 0.21 11.9 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 KRZ99173.1 - 0.00051 19.9 0.4 0.22 11.7 0.1 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 KRZ99173.1 - 0.00099 19.0 0.0 0.0077 16.2 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 KRZ99173.1 - 0.05 13.4 2.3 0.15 11.9 0.4 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat CSN8_PSD8_EIF3K PF10075.9 KRZ99173.1 - 0.064 13.2 0.1 0.13 12.2 0.1 1.6 1 0 0 1 1 1 0 CSN8/PSMD8/EIF3K family AstA PF04958.12 KRZ99173.1 - 0.092 11.3 0.0 0.14 10.6 0.0 1.3 1 0 0 1 1 1 0 Arginine N-succinyltransferase beta subunit TPR_14 PF13428.6 KRZ99173.1 - 0.13 13.2 0.0 1.2 10.1 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 KRZ99173.1 - 0.13 12.2 0.2 12 5.9 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 KRZ99173.1 - 0.26 11.6 3.7 0.35 11.2 0.0 3.2 4 0 0 4 4 3 0 Tetratricopeptide repeat PBECR1 PF18809.1 KRZ99173.1 - 3.2 8.5 4.8 11 6.8 0.2 2.6 3 0 0 3 3 2 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease1 DUF2048 PF09752.9 KRZ99176.1 - 0.037 13.1 0.0 0.041 13.0 0.0 1.1 1 0 0 1 1 1 0 Abhydrolase domain containing 18 TauD PF02668.16 KRZ99178.1 - 9.7e-59 199.3 2.2 1.3e-58 198.9 2.2 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Tho1_MOS11_C PF18592.1 KRZ99180.1 - 1e-22 79.7 2.5 1.9e-22 78.8 2.5 1.5 1 0 0 1 1 1 1 Tho1/MOS11 C-terminal domain SAP PF02037.27 KRZ99180.1 - 1.1e-11 44.2 0.0 2e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 SAP domain DUF2052 PF09747.9 KRZ99180.1 - 0.45 10.6 10.0 0.58 10.3 10.0 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Presenilin PF01080.17 KRZ99180.1 - 6.2 5.5 6.5 6.9 5.3 6.5 1.1 1 0 0 1 1 1 0 Presenilin DUF202 PF02656.15 KRZ99181.1 - 5e-20 71.7 0.5 5e-20 71.7 0.5 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) MCM PF00493.23 KRZ99182.1 - 7.9e-102 339.1 0.0 3.8e-101 336.8 0.0 1.9 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 KRZ99182.1 - 5.4e-32 110.3 0.2 1.1e-31 109.4 0.2 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KRZ99182.1 - 3.3e-22 78.7 1.3 1.6e-21 76.5 0.2 2.6 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 KRZ99182.1 - 5.4e-20 71.9 5.2 1.5e-19 70.5 5.2 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KRZ99182.1 - 9.2e-08 31.7 0.1 2.1e-05 24.0 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KRZ99182.1 - 6.6e-07 29.4 0.0 3.4e-06 27.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KRZ99182.1 - 0.0085 16.0 0.0 0.026 14.4 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 KRZ99182.1 - 0.057 13.9 0.1 0.38 11.2 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KRZ99182.1 - 0.1 12.3 0.1 0.68 9.6 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain PBP1_TM PF14812.6 KRZ99182.1 - 0.16 12.4 0.6 0.43 11.0 0.6 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal AAA_lid_2 PF17863.1 KRZ99182.1 - 0.18 11.6 0.0 0.42 10.5 0.0 1.5 1 0 0 1 1 1 0 AAA lid domain AAA_16 PF13191.6 KRZ99182.1 - 0.29 11.5 1.4 5.8 7.3 0.0 3.2 2 2 1 3 3 3 0 AAA ATPase domain Stb3 PF10330.9 KRZ99183.1 - 1.5e-29 101.9 0.9 2.2e-29 101.3 0.1 1.7 2 0 0 2 2 2 1 Putative Sin3 binding protein Spt5_N PF11942.8 KRZ99183.1 - 0.12 13.4 0.2 0.12 13.4 0.2 3.9 4 0 0 4 4 4 0 Spt5 transcription elongation factor, acidic N-terminal Stm1_N PF09598.10 KRZ99185.1 - 1.7e-09 38.4 2.9 1.7e-09 38.4 2.9 4.4 3 1 1 4 4 4 1 Stm1 LRR_8 PF13855.6 KRZ99187.1 - 3.1e-13 49.3 16.3 1.4e-09 37.5 1.2 4.4 3 1 1 4 4 4 2 Leucine rich repeat LRR_4 PF12799.7 KRZ99187.1 - 1.6e-09 37.9 26.5 2.8e-05 24.4 4.9 5.8 6 1 0 6 6 6 2 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KRZ99187.1 - 0.00066 19.6 0.5 0.00066 19.6 0.5 2.5 2 1 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 KRZ99187.1 - 0.0048 16.4 5.8 0.0048 16.4 5.8 2.8 2 1 1 3 3 3 2 Leucine-rich repeat Glyco_hydro_3_C PF01915.22 KRZ99189.1 - 4.6e-50 170.4 0.0 6.9e-50 169.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KRZ99189.1 - 5.1e-35 121.4 0.0 1.4e-34 120.0 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KRZ99189.1 - 4e-22 78.1 0.1 8.4e-22 77.1 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain MFS_1 PF07690.16 KRZ99190.1 - 1.4e-47 162.4 34.5 7.1e-47 160.0 34.5 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KRZ99190.1 - 1.7e-18 66.4 22.8 2.2e-18 66.0 22.8 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KRZ99190.1 - 9.5e-13 47.8 6.9 9.5e-13 47.8 6.9 2.9 3 0 0 3 3 3 2 Sugar (and other) transporter DUF2530 PF10745.9 KRZ99190.1 - 0.4 11.0 8.6 6.9 7.0 1.3 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2530) DNA_pol_E_B PF04042.16 KRZ99192.1 - 4.7e-44 150.3 0.3 7.5e-44 149.6 0.3 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Fib_alpha PF08702.10 KRZ99192.1 - 2.4 8.4 5.7 26 5.0 0.1 3.3 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Prenyltrans PF00432.21 KRZ99193.1 - 8.8e-53 175.7 2.9 6.1e-14 51.5 0.0 5.6 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 KRZ99193.1 - 0.00037 19.7 0.0 0.0039 16.3 0.0 2.3 1 1 1 2 2 2 1 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 KRZ99193.1 - 0.083 12.0 0.0 0.88 8.6 0.0 2.5 3 1 1 4 4 4 0 Squalene-hopene cyclase N-terminal domain Myb_DNA-bind_6 PF13921.6 KRZ99194.1 - 5.6e-12 45.7 0.1 1.5e-11 44.4 0.0 1.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KRZ99194.1 - 4.3e-10 39.6 0.5 6.9e-10 39.0 0.5 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain AAA PF00004.29 KRZ99195.1 - 4.8e-38 130.6 0.1 1.7e-37 128.8 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KRZ99195.1 - 3.1e-06 26.9 0.0 6.3e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 KRZ99195.1 - 3.3e-05 23.8 0.0 0.00023 21.1 0.0 2.4 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.12 KRZ99195.1 - 0.00013 21.7 0.0 0.00024 20.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KRZ99195.1 - 0.00019 21.7 0.8 0.0047 17.2 0.3 2.8 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.6 KRZ99195.1 - 0.00044 20.7 0.1 0.0022 18.4 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain TIP49 PF06068.13 KRZ99195.1 - 0.0007 18.9 0.0 0.0011 18.2 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_2 PF07724.14 KRZ99195.1 - 0.0025 17.9 0.0 0.0067 16.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KRZ99195.1 - 0.0028 17.7 0.0 0.011 15.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KRZ99195.1 - 0.0049 16.3 0.1 0.01 15.3 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KRZ99195.1 - 0.0085 15.8 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 KRZ99195.1 - 0.011 16.3 0.0 0.2 12.2 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KRZ99195.1 - 0.011 15.9 0.0 0.028 14.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 KRZ99195.1 - 0.023 13.9 0.0 0.044 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_25 PF13481.6 KRZ99195.1 - 0.026 14.1 0.1 0.083 12.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KRZ99195.1 - 0.041 13.8 0.2 0.26 11.2 0.0 2.4 2 0 0 2 2 2 0 NACHT domain AAA_14 PF13173.6 KRZ99195.1 - 0.045 13.8 0.0 0.24 11.4 0.0 2.3 3 0 0 3 3 2 0 AAA domain HMMR_C PF15908.5 KRZ99195.1 - 0.059 13.6 0.7 0.14 12.4 0.4 1.7 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor C-terminal AAA_7 PF12775.7 KRZ99195.1 - 0.07 12.6 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 KRZ99195.1 - 0.071 12.8 0.2 0.21 11.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 KRZ99195.1 - 0.08 12.2 0.2 1.1 8.5 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 KRZ99195.1 - 0.19 11.2 0.0 0.46 9.9 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein ATPase PF06745.13 KRZ99195.1 - 0.4 10.0 1.6 3.1 7.1 0.0 2.7 2 1 1 3 3 3 0 KaiC Ndc1_Nup PF09531.10 KRZ99195.1 - 9.5 4.8 15.3 0.22 10.2 3.7 2.2 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Tup_N PF08581.10 KRZ99196.1 - 0.027 14.8 0.0 0.052 13.9 0.0 1.5 1 0 0 1 1 1 0 Tup N-terminal Apq12 PF12716.7 KRZ99196.1 - 0.039 13.9 5.8 0.052 13.5 5.8 1.2 1 0 0 1 1 1 0 Nuclear pore assembly and biogenesis MFS_1 PF07690.16 KRZ99197.1 - 3.6e-09 36.0 16.6 4.4e-09 35.7 15.5 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Gpr1_Fun34_YaaH PF01184.19 KRZ99198.1 - 6.3e-93 310.1 27.2 7.2e-93 309.9 27.2 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF2070 PF09843.9 KRZ99198.1 - 6.5 4.9 12.6 7.7 4.7 12.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Thioredoxin PF00085.20 KRZ99199.1 - 1.1e-45 153.8 0.1 2e-25 88.7 0.1 2.3 2 0 0 2 2 2 2 Thioredoxin OST3_OST6 PF04756.13 KRZ99199.1 - 9.1e-17 61.3 0.1 8.3e-08 31.9 0.0 2.1 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 KRZ99199.1 - 6e-14 52.4 0.0 2e-06 28.2 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin-like domain ERp29 PF07749.12 KRZ99199.1 - 1.9e-12 47.9 0.7 3.9e-12 46.9 0.7 1.6 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_8 PF13905.6 KRZ99199.1 - 5.9e-12 45.8 1.2 3.6e-07 30.4 0.2 4.7 2 2 2 4 4 4 2 Thioredoxin-like AhpC-TSA PF00578.21 KRZ99199.1 - 3.2e-09 36.8 0.2 3.8e-07 30.0 0.1 2.6 2 0 0 2 2 2 1 AhpC/TSA family TraF PF13728.6 KRZ99199.1 - 2.2e-08 34.2 0.1 0.0051 16.7 0.0 2.5 3 0 0 3 3 3 2 F plasmid transfer operon protein Thioredoxin_7 PF13899.6 KRZ99199.1 - 7e-06 26.1 0.8 0.15 12.3 0.0 2.7 3 0 0 3 3 2 2 Thioredoxin-like ERp29_N PF07912.13 KRZ99199.1 - 2e-05 24.8 0.1 5.6e-05 23.3 0.1 1.8 1 0 0 1 1 1 1 ERp29, N-terminal domain Redoxin PF08534.10 KRZ99199.1 - 9.9e-05 22.1 0.2 0.27 10.9 0.0 2.7 3 0 0 3 3 3 2 Redoxin Thioredoxin_9 PF14595.6 KRZ99199.1 - 0.00027 20.7 0.6 0.03 14.1 0.0 2.8 3 0 0 3 3 3 1 Thioredoxin Thioredoxin_3 PF13192.6 KRZ99199.1 - 0.00063 19.7 0.0 0.39 10.8 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin domain Thioredoxin_5 PF13743.6 KRZ99199.1 - 0.01 15.6 0.0 5.3 6.7 0.0 2.8 2 0 0 2 2 2 0 Thioredoxin Thioredoxin_4 PF13462.6 KRZ99199.1 - 0.015 15.5 1.0 3.1 7.9 0.0 3.5 2 2 1 3 3 3 0 Thioredoxin HyaE PF07449.11 KRZ99199.1 - 0.028 14.4 0.0 9.2 6.3 0.0 2.5 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE PDCD7 PF16021.5 KRZ99199.1 - 0.052 12.7 0.1 0.083 12.0 0.1 1.2 1 0 0 1 1 1 0 Programmed cell death protein 7 Suc_Fer-like PF06999.12 KRZ99200.1 - 6e-48 163.3 0.0 7.2e-48 163.1 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like RNA_POL_M_15KD PF02150.16 KRZ99200.1 - 0.057 13.3 0.9 0.51 10.3 0.3 2.4 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit PIP5K PF01504.18 KRZ99201.1 - 5.9e-95 317.6 1.0 5.9e-95 317.6 1.0 2.1 3 0 0 3 3 3 1 Phosphatidylinositol-4-phosphate 5-Kinase AIM24 PF01987.17 KRZ99202.1 - 5e-23 82.0 0.0 6.5e-23 81.6 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 STE PF02200.16 KRZ99203.1 - 0.0016 18.8 0.3 0.0033 17.8 0.3 1.5 1 0 0 1 1 1 1 STE like transcription factor DUF155 PF02582.14 KRZ99204.1 - 3e-55 187.0 0.9 5.7e-55 186.1 0.9 1.5 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 UPF0449 PF15136.6 KRZ99204.1 - 0.019 15.4 0.9 0.056 13.9 0.1 2.2 2 1 0 2 2 2 0 Uncharacterised protein family UPF0449 DRIM PF07539.12 KRZ99205.1 - 6.7e-169 563.1 14.7 6.7e-169 563.1 14.7 5.9 6 2 1 7 7 7 2 Down-regulated in metastasis Swi3 PF07962.12 KRZ99205.1 - 0.044 13.8 0.0 0.83 9.7 0.0 3.0 2 0 0 2 2 2 0 Replication Fork Protection Component Swi3 HEAT PF02985.22 KRZ99205.1 - 0.13 12.6 2.7 98 3.6 0.0 5.6 6 0 0 6 6 6 0 HEAT repeat IKKbetaNEMObind PF12179.8 KRZ99205.1 - 1.1 9.4 3.3 0.82 9.8 0.1 2.7 2 0 0 2 2 2 0 I-kappa-kinase-beta NEMO binding domain HMG_box PF00505.19 KRZ99206.1 - 2e-15 56.9 2.3 2e-15 56.9 2.3 3.6 3 1 1 4 4 4 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KRZ99206.1 - 2.6e-12 47.1 1.3 2.6e-12 47.1 1.3 3.6 2 1 1 3 3 3 1 HMG-box domain DUF3987 PF13148.6 KRZ99206.1 - 4.4 6.2 19.1 0.93 8.4 6.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3987) ArfGap PF01412.18 KRZ99207.1 - 6.6e-33 113.3 1.7 8.6e-33 112.9 0.1 2.0 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf Tim44 PF04280.15 KRZ99208.1 - 2e-37 128.5 0.1 4.8e-37 127.3 0.1 1.6 1 0 0 1 1 1 1 Tim44-like domain Senescence PF06911.12 KRZ99208.1 - 0.025 14.9 5.1 0.055 13.8 5.0 1.7 1 1 0 1 1 1 0 Senescence-associated protein Phycobilisome PF00502.19 KRZ99208.1 - 0.048 13.6 0.1 0.11 12.4 0.1 1.7 1 0 0 1 1 1 0 Phycobilisome protein MapZ_EC1 PF18041.1 KRZ99208.1 - 0.58 10.4 5.8 0.66 10.2 2.0 2.9 3 1 1 4 4 4 0 MapZ extracellular domain 1 FAD_binding_3 PF01494.19 KRZ99209.1 - 4.4e-19 68.9 0.0 1e-18 67.8 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain SE PF08491.10 KRZ99209.1 - 3.1e-06 26.5 0.1 0.0012 17.9 0.0 2.6 2 1 1 3 3 3 2 Squalene epoxidase NAD_binding_8 PF13450.6 KRZ99209.1 - 2.9e-05 24.2 0.0 6.5e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KRZ99209.1 - 4.6e-05 23.9 0.1 0.0024 18.4 0.1 2.9 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KRZ99209.1 - 5e-05 23.0 0.0 0.00026 20.7 0.0 1.9 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KRZ99209.1 - 0.00036 19.9 0.0 0.0039 16.5 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 KRZ99209.1 - 0.0011 18.8 0.0 0.0019 18.1 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 KRZ99209.1 - 0.0023 17.1 0.0 0.0034 16.5 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KRZ99209.1 - 0.032 13.3 0.0 0.082 12.0 0.1 1.5 2 0 0 2 2 2 0 FAD binding domain ApbA PF02558.16 KRZ99209.1 - 0.057 13.1 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.21 KRZ99209.1 - 0.063 12.6 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 KRZ99209.1 - 0.069 12.7 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 KRZ99209.1 - 0.13 11.6 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_oxidored PF12831.7 KRZ99209.1 - 0.27 10.5 0.1 0.98 8.7 0.1 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase ABC_tran_CTD PF16326.5 KRZ99210.1 - 0.11 12.8 20.8 0.027 14.7 5.3 3.9 4 0 0 4 4 4 0 ABC transporter C-terminal domain FAM76 PF16046.5 KRZ99210.1 - 1.6 8.1 15.6 0.45 9.8 11.7 1.9 2 0 0 2 2 2 0 FAM76 protein TolA_bind_tri PF16331.5 KRZ99210.1 - 2.7 8.1 13.2 1 9.5 6.3 2.9 3 0 0 3 3 3 0 TolA binding protein trimerisation Peptidase_C48 PF02902.19 KRZ99211.1 - 1.4e-25 90.4 3.2 3e-25 89.3 3.2 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain KCNQC3-Ank-G_bd PF11956.8 KRZ99211.1 - 0.025 14.9 2.0 0.11 12.7 0.6 2.5 1 1 1 2 2 2 0 Ankyrin-G binding motif of KCNQ2-3 Alfin PF12165.8 KRZ99211.1 - 0.031 14.0 0.0 0.08 12.6 0.0 1.7 1 0 0 1 1 1 0 Alfin 4HBT PF03061.22 KRZ99212.1 - 1.6e-08 34.8 0.0 4e-08 33.5 0.0 1.6 2 0 0 2 2 2 1 Thioesterase superfamily RNA_bind PF08675.11 KRZ99212.1 - 0.11 12.5 0.1 0.18 11.8 0.1 1.3 1 0 0 1 1 1 0 RNA binding domain HSP9_HSP12 PF04119.12 KRZ99213.1 - 5.4e-23 81.2 7.5 6e-23 81.0 7.5 1.0 1 0 0 1 1 1 1 Heat shock protein 9/12 Thymidylat_synt PF00303.19 KRZ99214.1 - 3.3e-113 377.3 0.0 3.7e-113 377.1 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase Shugoshin_N PF07558.11 KRZ99215.1 - 1.1e-15 57.2 8.7 3.1e-15 55.8 8.7 1.8 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.11 KRZ99215.1 - 1e-08 34.8 10.3 3.3e-08 33.2 10.3 1.9 1 0 0 1 1 1 1 Shugoshin C terminus DASH_Dad2 PF08654.10 KRZ99216.1 - 6e-25 87.5 1.3 6e-25 87.5 1.3 2.4 2 1 0 2 2 2 1 DASH complex subunit Dad2 DASH_Duo1 PF08651.10 KRZ99216.1 - 0.015 15.0 1.1 0.033 14.0 1.1 1.5 1 0 0 1 1 1 0 DASH complex subunit Duo1 Seryl_tRNA_N PF02403.22 KRZ99216.1 - 0.046 13.9 1.5 0.046 13.9 1.5 2.0 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain NPV_P10 PF05531.12 KRZ99216.1 - 0.49 10.9 6.4 0.12 12.9 0.7 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein HAUS2 PF15003.6 KRZ99216.1 - 1 9.1 5.2 0.11 12.2 1.1 1.4 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 2 DUF1664 PF07889.12 KRZ99216.1 - 9 6.4 7.0 0.88 9.6 0.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Nucleoporin_N PF08801.11 KRZ99217.1 - 6e-71 239.5 3.3 8.4e-71 239.0 3.3 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 KRZ99217.1 - 2e-44 152.4 28.6 1e-43 150.0 28.6 2.0 1 1 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Hydrolase_6 PF13344.6 KRZ99217.1 - 0.093 12.8 0.0 0.35 11.0 0.0 2.0 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Brix PF04427.18 KRZ99218.1 - 7e-41 140.5 1.3 9.9e-41 140.0 1.3 1.2 1 0 0 1 1 1 1 Brix domain ABC_tran PF00005.27 KRZ99219.1 - 1.5e-48 164.8 0.1 7.3e-24 84.8 0.0 2.9 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 KRZ99219.1 - 1.4e-21 76.3 0.5 1.4e-21 76.3 0.5 3.4 4 0 0 4 4 2 1 ABC transporter AAA_21 PF13304.6 KRZ99219.1 - 5.6e-17 62.5 2.1 1.8e-05 24.7 0.1 4.3 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KRZ99219.1 - 4.1e-10 39.5 1.3 0.14 11.6 0.0 4.5 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KRZ99219.1 - 5.6e-09 36.6 0.1 7.4e-05 23.2 0.0 2.7 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 KRZ99219.1 - 5e-08 32.6 0.0 0.0034 17.1 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KRZ99219.1 - 5e-08 33.0 0.5 0.00024 21.1 0.0 3.1 3 0 0 3 3 3 2 RsgA GTPase AAA_23 PF13476.6 KRZ99219.1 - 1.3e-06 29.1 9.6 0.061 13.8 0.0 4.3 4 0 0 4 4 4 2 AAA domain AAA_22 PF13401.6 KRZ99219.1 - 1.2e-05 25.6 0.0 0.058 13.7 0.1 2.8 2 1 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 KRZ99219.1 - 1.8e-05 24.7 0.0 0.033 14.3 0.0 3.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase NACHT PF05729.12 KRZ99219.1 - 2e-05 24.6 0.2 0.11 12.4 0.0 2.7 2 0 0 2 2 2 2 NACHT domain RNA_helicase PF00910.22 KRZ99219.1 - 9e-05 22.8 0.0 0.81 10.1 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_28 PF13521.6 KRZ99219.1 - 9.3e-05 22.7 0.0 0.29 11.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain Roc PF08477.13 KRZ99219.1 - 0.00011 22.3 0.0 0.21 11.8 0.0 2.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_18 PF13238.6 KRZ99219.1 - 0.00012 22.6 0.0 0.11 13.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KRZ99219.1 - 0.00016 21.7 0.0 0.56 10.2 0.1 2.6 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 KRZ99219.1 - 0.00027 21.0 0.0 1.4 9.0 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 KRZ99219.1 - 0.0004 20.2 0.1 0.59 9.8 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA PF00004.29 KRZ99219.1 - 0.00044 20.7 0.0 1.1 9.7 0.0 2.9 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KRZ99219.1 - 0.00056 19.2 0.1 1.1 8.4 0.0 3.2 3 0 0 3 3 3 1 NB-ARC domain Dynamin_N PF00350.23 KRZ99219.1 - 0.00081 19.5 3.7 1.9 8.5 0.0 4.4 3 1 1 4 4 4 1 Dynamin family AAA_33 PF13671.6 KRZ99219.1 - 0.001 19.3 0.2 1.9 8.7 0.0 3.2 4 0 0 4 4 2 1 AAA domain AAA_7 PF12775.7 KRZ99219.1 - 0.0016 18.0 0.0 0.24 10.9 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region MCM PF00493.23 KRZ99219.1 - 0.0022 17.2 0.0 0.19 10.8 0.0 2.6 2 0 0 2 2 2 1 MCM P-loop domain AAA_25 PF13481.6 KRZ99219.1 - 0.0035 17.0 0.0 2.4 7.7 0.0 3.7 4 0 0 4 4 3 1 AAA domain Ras PF00071.22 KRZ99219.1 - 0.0056 16.3 0.0 3.1 7.4 0.0 2.7 3 0 0 3 3 3 1 Ras family AAA_30 PF13604.6 KRZ99219.1 - 0.0056 16.4 0.9 0.42 10.3 0.0 3.4 4 1 0 4 4 2 1 AAA domain DUF815 PF05673.13 KRZ99219.1 - 0.016 14.4 0.0 5.4 6.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Septin PF00735.18 KRZ99219.1 - 0.016 14.5 0.0 0.9 8.8 0.0 2.6 2 0 0 2 2 2 0 Septin AAA_15 PF13175.6 KRZ99219.1 - 0.018 14.7 16.5 0.045 13.5 0.0 4.0 3 2 2 5 5 4 0 AAA ATPase domain G-alpha PF00503.20 KRZ99219.1 - 0.019 14.1 0.0 4.5 6.3 0.0 2.8 2 1 1 3 3 3 0 G-protein alpha subunit NTPase_1 PF03266.15 KRZ99219.1 - 0.021 14.8 0.1 1.9 8.4 0.0 2.6 2 0 0 2 2 2 0 NTPase DAP3 PF10236.9 KRZ99219.1 - 0.025 13.8 0.1 6.5 5.8 0.0 2.7 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 FeoB_N PF02421.18 KRZ99219.1 - 0.048 13.2 0.1 2.6 7.5 0.1 2.7 2 0 0 2 2 2 0 Ferrous iron transport protein B PduV-EutP PF10662.9 KRZ99219.1 - 0.049 13.4 0.3 17 5.1 0.0 3.0 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_17 PF13207.6 KRZ99219.1 - 0.057 13.8 1.2 32 5.0 0.0 3.7 3 0 0 3 3 3 0 AAA domain DLIC PF05783.11 KRZ99219.1 - 0.061 12.2 0.0 0.81 8.4 0.0 2.3 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) Zeta_toxin PF06414.12 KRZ99219.1 - 0.08 12.2 1.5 1.8 7.8 0.0 2.8 3 0 0 3 3 3 0 Zeta toxin T2SSE PF00437.20 KRZ99219.1 - 0.093 11.8 0.0 0.34 9.9 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein MeaB PF03308.16 KRZ99219.1 - 0.096 11.7 0.0 7.6 5.4 0.0 2.6 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB TniB PF05621.11 KRZ99219.1 - 0.11 11.9 0.2 4.3 6.7 0.0 3.1 3 1 1 4 4 4 0 Bacterial TniB protein ATPase_2 PF01637.18 KRZ99219.1 - 0.3 10.9 6.6 2.7 7.8 0.0 3.3 4 0 0 4 4 2 0 ATPase domain predominantly from Archaea DUF87 PF01935.17 KRZ99219.1 - 0.75 9.8 3.8 16 5.5 0.0 3.5 3 1 1 4 4 3 0 Helicase HerA, central domain NARP1 PF12569.8 KRZ99219.1 - 1.6 7.5 7.5 2.7 6.8 7.5 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 AAA_27 PF13514.6 KRZ99219.1 - 6.4 6.3 9.8 3.8 7.0 0.0 3.6 4 0 0 4 4 2 0 AAA domain BLM10_mid PF16507.5 KRZ99220.1 - 2.3e-183 610.6 0.3 3.7e-183 609.9 0.3 1.4 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, mid region BLM10_N PF16547.5 KRZ99220.1 - 1e-30 105.9 0.2 3.9e-30 104.0 0.2 2.1 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, N-terminal DUF3437 PF11919.8 KRZ99220.1 - 2.4e-25 88.3 0.0 8.9e-25 86.4 0.0 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) CBM64 PF18666.1 KRZ99220.1 - 0.15 12.2 0.5 0.51 10.4 0.5 1.9 1 0 0 1 1 1 0 Carbohydrate-binding module 64 EF-hand_1 PF00036.32 KRZ99221.1 - 3.8e-14 51.1 1.6 0.00018 20.8 0.0 4.1 4 0 0 4 4 4 3 EF hand EF-hand_5 PF13202.6 KRZ99221.1 - 5.3e-12 44.7 0.8 6.9e-05 22.2 0.0 3.4 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 KRZ99221.1 - 3.6e-10 38.9 4.7 0.0056 16.5 0.0 3.7 3 0 0 3 3 3 3 EF-hand domain EF-hand_7 PF13499.6 KRZ99221.1 - 9.7e-09 35.6 4.9 2.5e-06 27.8 0.1 2.8 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KRZ99221.1 - 0.00018 21.3 2.1 0.32 10.9 0.0 3.7 4 0 0 4 4 4 2 EF-hand domain pair S10_plectin PF03501.15 KRZ99222.1 - 4.6e-39 132.4 0.0 5.3e-39 132.2 0.0 1.0 1 0 0 1 1 1 1 Plectin/S10 domain RQC PF09382.10 KRZ99222.1 - 0.055 13.3 0.0 0.11 12.3 0.0 1.5 2 0 0 2 2 2 0 RQC domain DUF4364 PF14277.6 KRZ99222.1 - 0.078 12.7 0.1 0.14 11.9 0.0 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4364) MsyB PF13984.6 KRZ99222.1 - 0.1 12.9 0.0 0.13 12.6 0.0 1.2 1 0 0 1 1 1 0 MsyB protein MuF_C PF18819.1 KRZ99224.1 - 0.026 14.5 0.0 0.068 13.2 0.0 1.7 1 0 0 1 1 1 0 Phage MuF-C-terminal domain Septin PF00735.18 KRZ99225.1 - 8e-87 291.1 0.1 1.4e-86 290.3 0.1 1.4 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KRZ99225.1 - 4.1e-07 30.1 0.0 9.3e-07 28.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KRZ99225.1 - 0.0041 17.0 1.8 0.03 14.2 0.3 2.3 2 0 0 2 2 2 1 RsgA GTPase AIG1 PF04548.16 KRZ99225.1 - 0.012 14.9 0.2 0.024 13.9 0.2 1.5 1 0 0 1 1 1 0 AIG1 family FtsK_SpoIIIE PF01580.18 KRZ99225.1 - 0.022 14.1 0.0 0.046 13.1 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_33 PF13671.6 KRZ99225.1 - 0.028 14.6 0.0 0.074 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 KRZ99225.1 - 0.028 14.0 0.2 0.067 12.8 0.1 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.6 KRZ99225.1 - 0.028 14.0 0.0 0.092 12.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KRZ99225.1 - 0.042 14.1 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KRZ99225.1 - 0.06 13.1 0.4 0.14 11.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KRZ99225.1 - 0.07 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI SRP54 PF00448.22 KRZ99225.1 - 0.13 11.8 0.2 4.3 6.9 0.1 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Dynamin_N PF00350.23 KRZ99225.1 - 0.22 11.6 4.6 0.24 11.4 0.1 2.9 2 1 1 3 3 3 0 Dynamin family ATP_bind_1 PF03029.17 KRZ99225.1 - 0.23 11.2 1.3 0.73 9.6 0.3 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein FeoB_N PF02421.18 KRZ99225.1 - 0.51 9.8 2.3 0.78 9.3 0.4 2.4 2 1 0 2 2 2 0 Ferrous iron transport protein B Asp PF00026.23 KRZ99226.1 - 1e-62 212.4 9.2 6e-53 180.3 4.7 2.1 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 KRZ99226.1 - 5.4e-11 43.1 0.5 9.3e-08 32.5 0.5 3.6 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KRZ99226.1 - 3.3e-08 34.1 0.0 0.37 11.5 0.0 3.7 3 0 0 3 3 3 3 Aspartyl protease gag-asp_proteas PF13975.6 KRZ99226.1 - 8.9e-07 29.4 0.0 1.6 9.4 0.0 4.0 4 0 0 4 4 4 3 gag-polyprotein putative aspartyl protease ADH_N PF08240.12 KRZ99227.1 - 6.9e-26 90.3 4.3 1.2e-25 89.6 4.0 1.5 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KRZ99227.1 - 2.4e-19 69.6 0.0 3.8e-19 69.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KRZ99227.1 - 2.4e-06 27.0 0.1 4.1e-06 26.3 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KRZ99227.1 - 2.9e-06 26.8 0.2 5.9e-06 25.8 0.2 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.6 KRZ99227.1 - 0.00026 22.0 0.0 0.00045 21.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Sacchrp_dh_NADP PF03435.18 KRZ99227.1 - 0.0014 18.9 0.1 0.0045 17.3 0.1 1.8 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain 3HCDH_N PF02737.18 KRZ99227.1 - 0.0031 17.4 0.1 0.0051 16.7 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 KRZ99227.1 - 0.0042 17.5 0.0 0.0081 16.6 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding ELFV_dehydrog PF00208.21 KRZ99227.1 - 0.0089 15.8 0.9 0.021 14.6 0.9 1.7 1 1 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ApbA PF02558.16 KRZ99227.1 - 0.029 14.0 0.1 0.046 13.4 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Oxidored_nitro PF00148.19 KRZ99227.1 - 0.1 11.3 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase Aldo_ket_red PF00248.21 KRZ99228.1 - 1.8e-64 217.8 0.0 2e-64 217.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HTH_23 PF13384.6 KRZ99228.1 - 0.028 14.2 0.1 0.079 12.8 0.1 1.7 1 0 0 1 1 1 0 Homeodomain-like domain OPT PF03169.15 KRZ99229.1 - 3.2e-139 465.4 41.5 3.6e-139 465.2 41.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein LIP PF03583.14 KRZ99230.1 - 9.6e-86 287.6 0.1 1.2e-85 287.3 0.1 1.1 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_1 PF00561.20 KRZ99230.1 - 0.0099 15.5 0.0 0.051 13.2 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KRZ99230.1 - 0.059 12.6 0.2 7.2 5.8 0.0 2.3 2 1 0 2 2 2 0 Serine aminopeptidase, S33 Sugar_tr PF00083.24 KRZ99231.1 - 3.1e-66 224.1 23.2 3.8e-66 223.8 23.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KRZ99231.1 - 3e-28 98.8 24.6 3e-28 98.8 24.6 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Phage_holin_4_1 PF05105.12 KRZ99231.1 - 0.084 13.0 2.1 0.26 11.4 2.1 1.8 1 0 0 1 1 1 0 Bacteriophage holin family Glyco_hydro_72 PF03198.14 KRZ99232.1 - 8.3e-142 472.1 12.5 1.1e-141 471.7 12.5 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 KRZ99232.1 - 2.9e-27 95.2 5.1 9.3e-27 93.5 5.1 2.0 1 0 0 1 1 1 1 X8 domain Cellulase PF00150.18 KRZ99232.1 - 3.9e-05 23.2 0.5 0.0076 15.7 0.2 2.2 1 1 1 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.17 KRZ99232.1 - 0.00047 19.4 2.9 0.003 16.7 2.9 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain 3Beta_HSD PF01073.19 KRZ99233.1 - 1.9e-84 283.0 0.0 2.3e-84 282.7 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KRZ99233.1 - 1.7e-32 112.8 0.0 2.2e-32 112.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KRZ99233.1 - 8.8e-21 74.6 0.0 2.4e-20 73.2 0.0 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KRZ99233.1 - 1e-14 54.3 0.0 2.9e-13 49.6 0.0 2.3 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.17 KRZ99233.1 - 1e-11 44.5 0.0 1.5e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 KRZ99233.1 - 4.5e-11 43.0 0.0 8e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KRZ99233.1 - 3.5e-08 32.9 0.0 6.1e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 KRZ99233.1 - 0.0011 19.0 0.0 0.0072 16.2 0.0 2.1 1 1 0 1 1 1 1 KR domain NmrA PF05368.13 KRZ99233.1 - 0.0011 18.6 0.0 0.0017 18.0 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.24 KRZ99233.1 - 0.0029 18.0 0.0 0.0065 16.9 0.0 1.6 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain TAXi_C PF14541.6 KRZ99233.1 - 0.023 14.5 0.0 0.035 13.9 0.0 1.2 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal FtsJ PF01728.19 KRZ99233.1 - 0.033 14.3 0.0 0.054 13.6 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_2 PF00891.18 KRZ99233.1 - 0.098 11.9 0.0 0.2 10.9 0.0 1.5 1 0 0 1 1 1 0 O-methyltransferase domain NAD_binding_9 PF13454.6 KRZ99233.1 - 0.12 12.4 0.0 0.62 10.0 0.0 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding Mus7 PF09462.10 KRZ99235.1 - 6.7e-94 315.9 27.0 1.2e-92 311.8 27.0 2.3 1 1 0 1 1 1 1 Mus7/MMS22 family SANT_DAMP1_like PF16282.5 KRZ99236.1 - 1.6e-19 69.9 5.6 4.5e-18 65.2 0.6 2.7 2 0 0 2 2 2 2 SANT/Myb-like domain of DAMP1 Myb_DNA-binding PF00249.31 KRZ99236.1 - 0.0088 16.2 0.1 0.035 14.3 0.1 2.1 1 0 0 1 1 1 1 Myb-like DNA-binding domain Mem_trans PF03547.18 KRZ99236.1 - 0.17 10.3 5.0 0.19 10.1 5.0 1.2 1 0 0 1 1 1 0 Membrane transport protein Zip PF02535.22 KRZ99236.1 - 1.4 8.1 11.4 3.1 6.9 11.4 1.6 1 0 0 1 1 1 0 ZIP Zinc transporter TFIIF_alpha PF05793.12 KRZ99236.1 - 2.8 6.4 46.1 0.34 9.4 41.2 1.9 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Cullin PF00888.22 KRZ99237.1 - 3.9e-155 517.9 20.9 5.8e-155 517.4 20.9 1.3 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KRZ99237.1 - 5.4e-26 90.4 4.6 2.2e-25 88.5 4.6 2.2 1 0 0 1 1 1 1 Cullin protein neddylation domain HSBP1 PF06825.12 KRZ99237.1 - 0.078 12.8 0.4 0.26 11.2 0.4 2.0 1 0 0 1 1 1 0 Heat shock factor binding protein 1 Aconitase PF00330.20 KRZ99238.1 - 1.1e-161 539.0 0.0 1.3e-161 538.7 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KRZ99238.1 - 4e-42 143.6 0.0 7.9e-42 142.7 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.13 KRZ99238.1 - 0.014 14.1 0.0 0.025 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF521) Cnd2 PF05786.14 KRZ99239.1 - 9.3e-152 507.4 37.7 1.1e-150 503.9 37.7 2.0 1 1 0 1 1 1 1 Condensin complex subunit 2 CNDH2_N PF06278.11 KRZ99239.1 - 0.0034 17.6 1.9 0.0091 16.2 0.1 2.7 2 0 0 2 2 2 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal CTP_transf_like PF01467.26 KRZ99240.1 - 3.3e-32 111.6 0.0 6.7e-32 110.6 0.0 1.5 2 0 0 2 2 2 1 Cytidylyltransferase-like E1-E2_ATPase PF00122.20 KRZ99241.1 - 1e-32 113.2 28.6 7.9e-29 100.5 0.6 4.4 5 0 0 5 5 5 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 KRZ99241.1 - 3.5e-27 95.3 2.8 3.5e-27 95.3 2.8 3.0 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 KRZ99241.1 - 7.7e-20 70.8 0.0 1.8e-19 69.6 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KRZ99241.1 - 4.7e-19 69.5 0.0 1.9e-17 64.3 0.0 2.8 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KRZ99241.1 - 9.1e-12 44.5 0.0 4.9e-11 42.1 0.0 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KRZ99241.1 - 3.5e-05 23.7 1.1 0.00095 19.0 1.0 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF1286 PF06939.11 KRZ99241.1 - 0.58 10.4 4.9 0.29 11.4 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1286) His_Phos_1 PF00300.22 KRZ99242.1 - 6.9e-34 117.2 0.0 9.6e-34 116.8 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Pantoate_transf PF02548.15 KRZ99243.1 - 1.5e-100 335.9 0.0 1.8e-100 335.6 0.0 1.1 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 KRZ99243.1 - 0.0017 17.9 0.0 0.0025 17.3 0.0 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Glyoxalase PF00903.25 KRZ99244.1 - 1.1e-31 109.7 0.0 4e-15 56.1 0.0 2.5 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KRZ99244.1 - 1e-11 45.0 0.0 5e-05 23.5 0.0 3.6 1 1 2 3 3 3 3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily CppA_N PF14506.6 KRZ99244.1 - 0.00012 22.1 0.0 0.44 10.6 0.0 2.7 2 0 0 2 2 2 2 CppA N-terminal Glyoxalase_2 PF12681.7 KRZ99244.1 - 0.00016 21.6 0.2 2.9 7.8 0.0 4.3 4 1 0 4 4 4 1 Glyoxalase-like domain Glyoxalase_6 PF18029.1 KRZ99244.1 - 0.0013 19.5 0.0 1.2 10.0 0.0 2.9 3 1 0 3 3 3 2 Glyoxalase-like domain Glyoxalase_3 PF13468.6 KRZ99244.1 - 0.03 14.4 0.0 2.1 8.5 0.0 2.4 2 0 0 2 2 2 0 Glyoxalase-like domain PRT_C PF08372.10 KRZ99244.1 - 0.093 12.5 0.1 3.8 7.3 0.0 2.2 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal Glutaredoxin PF00462.24 KRZ99245.1 - 1.2e-17 63.9 0.0 1.8e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_3 PF13192.6 KRZ99245.1 - 0.00058 19.9 0.0 0.00082 19.4 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_4 PF13462.6 KRZ99245.1 - 0.013 15.6 0.3 5.5 7.1 0.0 2.2 1 1 1 2 2 2 0 Thioredoxin DUF953 PF06110.11 KRZ99245.1 - 0.044 13.4 0.1 0.15 11.7 0.1 1.8 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF953) Thioredoxin_2 PF13098.6 KRZ99245.1 - 0.058 13.9 0.1 0.079 13.4 0.1 1.3 1 1 0 1 1 1 0 Thioredoxin-like domain Inos-1-P_synth PF01658.17 KRZ99245.1 - 0.088 13.1 0.2 1.5 9.1 0.0 2.0 2 0 0 2 2 2 0 Myo-inositol-1-phosphate synthase DSBA PF01323.20 KRZ99245.1 - 0.11 12.3 0.3 9.3 6.0 0.1 2.1 1 1 1 2 2 2 0 DSBA-like thioredoxin domain ABC_tran PF00005.27 KRZ99246.1 - 1.2e-42 145.7 7.0 3.9e-21 76.0 0.1 3.4 3 1 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 KRZ99246.1 - 4e-21 74.9 4.4 4e-21 74.9 4.4 3.8 4 0 0 4 4 4 1 ABC transporter AAA_21 PF13304.6 KRZ99246.1 - 4.8e-18 66.0 4.0 0.00016 21.6 0.0 5.1 5 0 0 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KRZ99246.1 - 1.8e-08 34.1 2.6 0.0012 18.3 0.5 3.8 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 KRZ99246.1 - 4.6e-07 30.2 0.7 0.014 15.7 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.6 KRZ99246.1 - 2.7e-06 27.9 4.6 0.11 13.1 0.0 4.2 4 1 0 4 4 4 2 AAA domain AAA_22 PF13401.6 KRZ99246.1 - 4.7e-06 26.9 1.6 0.22 11.8 0.0 3.7 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.6 KRZ99246.1 - 6.6e-06 25.8 0.1 0.11 12.3 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KRZ99246.1 - 1.2e-05 25.3 0.1 0.05 13.5 0.0 2.9 2 0 0 2 2 2 2 RsgA GTPase AAA PF00004.29 KRZ99246.1 - 2.9e-05 24.5 0.8 0.31 11.5 0.1 4.4 4 1 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KRZ99246.1 - 6.6e-05 23.3 0.4 0.29 11.5 0.0 3.0 3 0 0 3 3 2 2 AAA ATPase domain AAA_30 PF13604.6 KRZ99246.1 - 0.0001 22.1 0.0 0.34 10.6 0.0 3.7 4 0 0 4 4 3 1 AAA domain AAA_33 PF13671.6 KRZ99246.1 - 0.00018 21.7 2.7 0.093 12.9 0.0 3.3 3 2 0 3 3 3 1 AAA domain AAA_24 PF13479.6 KRZ99246.1 - 0.00038 20.2 0.1 0.64 9.7 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.6 KRZ99246.1 - 0.00038 21.0 29.5 0.21 12.1 0.0 5.2 5 0 0 5 5 5 2 AAA domain NACHT PF05729.12 KRZ99246.1 - 0.00052 20.0 0.3 0.94 9.4 0.0 2.5 2 0 0 2 2 2 2 NACHT domain RNA_helicase PF00910.22 KRZ99246.1 - 0.00058 20.2 0.3 2 8.8 0.0 3.3 3 0 0 3 3 2 1 RNA helicase NTPase_1 PF03266.15 KRZ99246.1 - 0.00062 19.7 0.1 0.12 12.3 0.0 2.9 2 0 0 2 2 2 1 NTPase AAA_7 PF12775.7 KRZ99246.1 - 0.00073 19.1 0.0 0.47 10.0 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region MMR_HSR1 PF01926.23 KRZ99246.1 - 0.00098 19.2 2.0 0.14 12.3 0.2 3.3 3 1 0 3 3 3 1 50S ribosome-binding GTPase AAA_14 PF13173.6 KRZ99246.1 - 0.001 19.1 0.7 0.44 10.6 0.0 3.7 2 1 1 3 3 3 1 AAA domain Roc PF08477.13 KRZ99246.1 - 0.0033 17.6 0.1 2.5 8.4 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase ATP-synt_ab PF00006.25 KRZ99246.1 - 0.0058 16.3 0.0 0.14 11.8 0.0 2.7 3 0 0 3 3 3 1 ATP synthase alpha/beta family, nucleotide-binding domain PduV-EutP PF10662.9 KRZ99246.1 - 0.0065 16.2 0.1 3.2 7.5 0.0 2.6 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation MeaB PF03308.16 KRZ99246.1 - 0.012 14.6 0.1 0.6 9.0 0.0 2.5 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MobB PF03205.14 KRZ99246.1 - 0.012 15.5 0.1 0.69 9.8 0.0 2.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.14 KRZ99246.1 - 0.022 14.7 0.5 1.1 9.2 0.0 2.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Thymidylate_kin PF02223.17 KRZ99246.1 - 0.028 14.1 3.2 3.8 7.1 0.1 3.9 3 0 0 3 3 3 0 Thymidylate kinase TsaE PF02367.17 KRZ99246.1 - 0.03 14.3 0.0 4 7.5 0.0 2.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRP54 PF00448.22 KRZ99246.1 - 0.074 12.7 2.3 9.6 5.8 0.1 3.7 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain T2SSE PF00437.20 KRZ99246.1 - 0.08 12.0 0.1 0.86 8.6 0.0 2.3 2 1 0 2 2 2 0 Type II/IV secretion system protein AAA_15 PF13175.6 KRZ99246.1 - 0.093 12.4 0.1 0.041 13.6 1.7 5.1 5 2 0 5 5 4 0 AAA ATPase domain AAA_19 PF13245.6 KRZ99246.1 - 0.11 12.8 1.3 1.1 9.5 0.0 3.0 4 0 0 4 4 3 0 AAA domain Pox_A32 PF04665.12 KRZ99246.1 - 0.13 11.7 6.8 0.48 9.8 0.0 3.8 4 1 1 5 5 5 0 Poxvirus A32 protein cobW PF02492.19 KRZ99246.1 - 0.27 10.8 2.2 19 4.8 0.3 2.9 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain NPV_P10 PF05531.12 KRZ99246.1 - 1.6 9.3 7.9 17 6.0 0.1 4.0 4 0 0 4 4 3 0 Nucleopolyhedrovirus P10 protein Dynamin_N PF00350.23 KRZ99246.1 - 5.1 7.1 16.7 0.087 12.9 0.8 4.3 3 2 1 4 4 4 0 Dynamin family AAA_17 PF13207.6 KRZ99246.1 - 6.3 7.2 8.6 39 4.7 0.1 4.2 3 1 0 3 3 3 0 AAA domain Lactamase_B_2 PF12706.7 KRZ99247.1 - 5.9e-28 97.8 0.0 1.1e-27 96.9 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KRZ99247.1 - 9.3e-12 45.1 0.0 1.3e-11 44.7 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Romo1 PF10247.9 KRZ99248.1 - 1.2e-26 92.8 12.6 1.6e-26 92.5 12.6 1.1 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 DUF1690 PF07956.11 KRZ99249.1 - 6.3e-43 146.5 6.0 7.1e-43 146.4 6.0 1.0 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) DRE2_N PF16803.5 KRZ99249.1 - 0.03 14.6 0.3 0.04 14.2 0.3 1.2 1 0 0 1 1 1 0 Fe-S cluster assembly protein DRE2 N-terminus FtsH_ext PF06480.15 KRZ99249.1 - 4 7.8 6.7 7.3 7.0 6.7 1.5 1 1 0 1 1 1 0 FtsH Extracellular UCH PF00443.29 KRZ99250.1 - 1.2e-47 162.6 4.4 1.6e-47 162.2 4.4 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KRZ99250.1 - 4e-12 46.4 13.2 4.5e-08 33.1 7.0 2.4 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 KRZ99250.1 - 7.8e-11 41.6 0.2 2.7e-10 39.8 0.2 2.0 1 0 0 1 1 1 1 Ubiquitin family TBK1_ULD PF18396.1 KRZ99250.1 - 0.031 14.2 0.0 0.075 13.0 0.0 1.6 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Aldedh PF00171.22 KRZ99251.1 - 4.3e-71 239.8 0.0 5.5e-71 239.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Chol_subst-bind PF09129.11 KRZ99251.1 - 0.059 12.3 0.0 0.091 11.7 0.0 1.2 1 0 0 1 1 1 0 Cholesterol oxidase, substrate-binding Flavoprotein PF02441.19 KRZ99252.1 - 9.9e-36 122.9 0.2 1.9e-35 122.0 0.0 1.6 2 0 0 2 2 2 1 Flavoprotein DNA_pol_phi PF04931.13 KRZ99252.1 - 0.00039 18.7 37.5 0.00061 18.1 37.5 1.2 1 0 0 1 1 1 1 DNA polymerase phi CDC45 PF02724.14 KRZ99252.1 - 0.099 10.9 25.1 0.15 10.4 25.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 KRZ99252.1 - 0.13 10.4 32.4 0.21 9.8 32.4 1.2 1 0 0 1 1 1 0 Nop14-like family RRN3 PF05327.11 KRZ99252.1 - 0.21 10.1 22.5 0.31 9.5 22.5 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CobT PF06213.12 KRZ99252.1 - 0.41 10.0 20.5 0.71 9.2 20.5 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF2457 PF10446.9 KRZ99252.1 - 0.81 8.8 53.1 0.071 12.2 41.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) SDA1 PF05285.12 KRZ99252.1 - 3.3 7.1 35.3 5.7 6.3 35.3 1.3 1 0 0 1 1 1 0 SDA1 TFB6 PF17110.5 KRZ99252.1 - 4.4 7.0 12.5 11 5.7 12.5 1.8 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Imm39 PF15568.6 KRZ99253.1 - 0.0061 16.7 0.1 0.056 13.5 0.0 2.2 2 0 0 2 2 2 1 Immunity protein 39 Peptidase_S9 PF00326.21 KRZ99253.1 - 0.032 13.7 0.0 0.73 9.3 0.0 2.7 2 1 0 2 2 2 0 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KRZ99253.1 - 0.082 12.2 0.0 1.6 8.0 0.0 2.4 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 KRZ99253.1 - 0.1 12.4 0.0 0.3 10.9 0.0 1.8 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase WD40 PF00400.32 KRZ99254.1 - 3.4e-06 27.7 0.7 0.3 12.0 0.0 3.9 4 0 0 4 4 4 2 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KRZ99254.1 - 0.019 14.0 0.1 0.078 11.9 0.0 2.0 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein CDC45 PF02724.14 KRZ99254.1 - 0.082 11.2 7.1 0.11 10.7 7.1 1.1 1 0 0 1 1 1 0 CDC45-like protein CSRNP_N PF16019.5 KRZ99254.1 - 0.17 11.8 3.5 0.38 10.6 3.5 1.5 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus DUF2457 PF10446.9 KRZ99254.1 - 1.1 8.4 14.4 1.6 7.8 14.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.12 KRZ99254.1 - 8.9 5.5 9.3 17 4.6 9.3 1.4 1 0 0 1 1 1 0 NOA36 protein Exo_endo_phos PF03372.23 KRZ99255.1 - 1.7e-10 40.8 0.1 3.5e-10 39.8 0.1 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Calreticulin PF00262.18 KRZ99256.1 - 9.3e-153 508.4 10.1 1.5e-152 507.8 10.1 1.3 1 0 0 1 1 1 1 Calreticulin family Alb1 PF09135.11 KRZ99257.1 - 6.3e-25 88.1 12.5 6.3e-25 88.1 12.5 2.0 2 0 0 2 2 2 1 Alb1 SusD-like_3 PF14322.6 KRZ99257.1 - 0.01 16.2 2.9 0.012 16.0 2.4 1.3 1 1 0 1 1 1 1 Starch-binding associating with outer membrane DUF3993 PF13158.6 KRZ99257.1 - 0.032 14.5 0.4 0.053 13.7 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3993) BSD PF03909.17 KRZ99258.1 - 3.5e-21 75.0 4.4 8e-13 48.2 0.0 3.4 3 0 0 3 3 3 2 BSD domain PH_TFIIH PF08567.11 KRZ99258.1 - 1e-11 45.0 0.6 3.9e-11 43.1 0.1 2.3 2 0 0 2 2 2 1 TFIIH p62 subunit, N-terminal domain CDC24 PF06395.11 KRZ99258.1 - 0.028 14.7 0.2 0.15 12.3 0.0 2.3 2 0 0 2 2 2 0 CDC24 Calponin Coa1 PF08695.10 KRZ99259.1 - 2e-45 153.3 0.1 2.7e-45 152.9 0.1 1.2 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 SKG6 PF08693.10 KRZ99260.1 - 0.12 11.8 0.4 0.4 10.1 0.0 2.1 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Peptidase_M48 PF01435.18 KRZ99261.1 - 1.6e-26 93.3 0.0 2.6e-26 92.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 Yos9_DD PF17880.1 KRZ99261.1 - 0.00017 21.7 0.2 0.026 14.6 0.0 3.2 2 1 0 3 3 3 1 Yos9 dimerzation domain Prefoldin_3 PF13758.6 KRZ99262.1 - 0.0027 17.7 0.8 0.0053 16.8 0.8 1.4 1 0 0 1 1 1 1 Prefoldin subunit Ac110_PIF PF07280.11 KRZ99262.1 - 0.19 11.6 2.3 0.28 11.0 0.2 2.3 3 0 0 3 3 3 0 Per os infectivity factor AC110 Kin17_mid PF10357.9 KRZ99263.1 - 4e-40 136.6 8.2 9.2e-40 135.5 8.2 1.6 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.8 KRZ99263.1 - 3.5e-07 30.4 3.9 3.5e-07 30.4 3.9 2.6 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KRZ99263.1 - 0.00055 20.2 2.8 0.0014 18.9 2.8 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KRZ99263.1 - 0.023 15.0 0.2 0.023 15.0 0.2 2.4 3 1 0 3 3 3 0 C2H2 type zinc-finger (2 copies) AKAP95 PF04988.12 KRZ99263.1 - 0.083 13.1 11.7 0.18 12.0 11.7 1.6 1 1 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_4 PF13894.6 KRZ99263.1 - 0.089 13.7 0.6 0.23 12.4 0.6 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KRZ99263.1 - 0.13 12.8 1.6 0.3 11.6 1.6 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF3835 PF12927.7 KRZ99263.1 - 0.83 10.5 8.8 0.16 12.9 4.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3835) UCH PF00443.29 KRZ99264.1 - 1e-50 172.6 3.5 1e-50 172.6 3.5 2.0 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KRZ99264.1 - 4.8e-15 56.0 0.9 2.7e-14 53.5 0.9 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Myb_DNA-binding PF00249.31 KRZ99265.1 - 1.4e-33 114.8 12.5 5e-14 52.2 0.5 3.7 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KRZ99265.1 - 1.1e-29 102.4 7.8 2.5e-11 43.6 0.1 3.9 2 1 1 3 3 3 3 Myb-like DNA-binding domain SLIDE PF09111.10 KRZ99265.1 - 4.6e-06 26.6 1.2 0.2 11.7 0.0 4.8 5 0 0 5 5 5 2 SLIDE Myb_DNA-bind_4 PF13837.6 KRZ99265.1 - 0.017 15.5 10.4 0.055 13.9 0.2 4.0 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain THF_DHG_CYH PF00763.23 KRZ99266.1 - 5.4e-27 94.4 0.0 9.4e-27 93.6 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 KRZ99266.1 - 1.7e-17 63.2 0.1 1e-14 54.2 0.1 2.9 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_2 PF03446.15 KRZ99266.1 - 0.14 12.3 0.0 0.3 11.2 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase RabGAP-TBC PF00566.18 KRZ99267.1 - 2.4e-46 158.1 9.8 1.3e-45 155.7 9.8 2.3 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Voldacs PF03517.13 KRZ99267.1 - 0.065 13.3 1.0 0.21 11.7 1.0 1.8 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling P5-ATPase PF12409.8 KRZ99267.1 - 0.36 10.9 3.1 1.1 9.3 0.0 2.7 3 0 0 3 3 3 0 P5-type ATPase cation transporter HSP70 PF00012.20 KRZ99268.1 - 2.2e-76 257.4 7.5 1.2e-75 255.0 6.6 1.9 2 0 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 KRZ99268.1 - 9.9e-09 34.4 0.4 1.5e-08 33.8 0.4 1.3 1 0 0 1 1 1 1 MreB/Mbl protein SpuA_C PF18033.1 KRZ99268.1 - 0.0028 17.6 0.0 0.13 12.3 0.0 2.8 2 0 0 2 2 2 1 SpuA C-terminal STE2 PF02116.15 KRZ99269.1 - 3.9e-84 282.3 26.2 4.9e-84 282.0 26.2 1.1 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR GSH_synth_ATP PF03917.17 KRZ99269.1 - 0.0045 15.8 0.1 0.0067 15.2 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain AMPK1_CBM PF16561.5 KRZ99270.1 - 1.8e-29 101.7 0.1 4.1e-29 100.6 0.1 1.6 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 KRZ99270.1 - 3.4e-28 97.7 3.3 9.3e-28 96.3 2.6 2.1 2 0 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interaction domain FAD_binding_3 PF01494.19 KRZ99271.1 - 2.3e-20 73.2 0.0 3.7e-20 72.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain SE PF08491.10 KRZ99271.1 - 0.0056 15.8 0.0 0.019 14.0 0.0 1.7 2 0 0 2 2 2 1 Squalene epoxidase DAO PF01266.24 KRZ99271.1 - 0.035 13.7 0.0 1.8 8.0 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KRZ99271.1 - 0.15 11.3 0.1 4.7 6.4 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Cpn60_TCP1 PF00118.24 KRZ99272.1 - 2.1e-142 475.2 14.4 2.4e-142 475.0 14.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PAD_M PF08527.10 KRZ99272.1 - 0.069 12.8 0.4 0.85 9.3 0.1 2.3 2 0 0 2 2 2 0 Protein-arginine deiminase (PAD) middle domain CRM1_repeat PF18777.1 KRZ99272.1 - 0.16 11.5 0.0 0.34 10.5 0.0 1.5 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat Mito_carr PF00153.27 KRZ99273.1 - 1.2e-60 201.5 3.0 1.2e-21 76.4 0.1 3.7 4 0 0 4 4 4 3 Mitochondrial carrier protein EF-hand_1 PF00036.32 KRZ99273.1 - 8.6e-22 75.0 17.3 1e-07 31.0 0.4 4.6 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KRZ99273.1 - 1.1e-17 64.2 14.0 5.7e-09 36.3 3.4 4.3 3 1 0 4 4 4 2 EF-hand domain pair EF-hand_6 PF13405.6 KRZ99273.1 - 5.2e-17 60.3 15.6 2.8e-05 23.7 0.2 5.0 5 0 0 5 5 5 4 EF-hand domain EF-hand_8 PF13833.6 KRZ99273.1 - 7.9e-16 57.7 15.2 4.5e-08 32.8 1.9 4.4 2 1 3 5 5 5 4 EF-hand domain pair EF-hand_5 PF13202.6 KRZ99273.1 - 5.5e-14 50.9 12.3 1.3e-06 27.6 0.2 4.4 4 0 0 4 4 4 3 EF hand SPARC_Ca_bdg PF10591.9 KRZ99273.1 - 0.00041 20.7 3.9 0.0032 17.8 0.7 2.7 1 1 2 3 3 3 3 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KRZ99273.1 - 0.00045 20.1 8.0 0.0084 16.0 0.2 3.2 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_11 PF08976.11 KRZ99273.1 - 0.019 15.9 4.0 0.5 11.3 0.7 3.4 2 1 1 3 3 3 0 EF-hand domain DIPSY PF11763.8 KRZ99273.1 - 0.023 14.8 2.4 0.047 13.9 1.3 1.9 1 1 1 2 2 2 0 Cell-wall adhesin ligand-binding C-terminal EF-hand_10 PF14788.6 KRZ99273.1 - 0.044 13.7 1.4 3.2 7.7 0.1 3.0 2 1 1 3 3 3 0 EF hand p25-alpha PF05517.12 KRZ99273.1 - 0.072 13.2 5.2 3.1 8.0 3.9 3.2 1 1 3 4 4 4 0 p25-alpha Mito_carr PF00153.27 KRZ99274.1 - 7.1e-61 202.2 1.8 4e-20 71.5 0.0 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 KRZ99274.1 - 3.9e-23 81.7 14.5 5.6e-12 45.9 2.7 3.4 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 KRZ99274.1 - 2.3e-22 76.8 20.5 3.8e-05 22.9 0.7 4.9 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.6 KRZ99274.1 - 2.4e-20 70.6 18.8 3.1e-05 23.6 0.1 4.6 3 1 1 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 KRZ99274.1 - 1.5e-16 59.9 12.3 2.3e-06 27.4 0.1 4.4 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 KRZ99274.1 - 5.4e-12 44.6 14.5 0.00093 18.6 0.3 4.6 4 0 0 4 4 4 3 EF hand SPARC_Ca_bdg PF10591.9 KRZ99274.1 - 1.6e-06 28.4 2.8 0.0064 16.8 0.5 2.4 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region p25-alpha PF05517.12 KRZ99274.1 - 6.1e-05 23.2 5.2 0.031 14.4 0.3 3.4 1 1 2 3 3 3 2 p25-alpha EF-hand_9 PF14658.6 KRZ99274.1 - 0.00018 21.8 1.2 0.22 11.9 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain Dockerin_1 PF00404.18 KRZ99274.1 - 0.031 14.5 8.4 9.6 6.5 0.7 3.8 2 1 2 4 4 4 0 Dockerin type I domain Serine_protease PF18405.1 KRZ99274.1 - 0.053 12.7 0.1 0.71 9.0 0.0 2.4 2 0 0 2 2 2 0 Gammaproteobacterial serine protease DUF3811 PF11656.8 KRZ99274.1 - 0.2 12.1 1.0 0.4 11.1 1.0 1.4 1 0 0 1 1 1 0 YjbD family (DUF3811) P63C PF10546.9 KRZ99275.1 - 0.084 13.5 0.3 12 6.5 0.0 2.8 3 0 0 3 3 3 0 P63C domain HORMA PF02301.18 KRZ99275.1 - 0.13 11.8 3.8 0.25 10.9 3.8 1.5 1 1 0 1 1 1 0 HORMA domain MutL_C PF08676.11 KRZ99276.1 - 3.9e-24 85.1 0.1 8.3e-24 84.0 0.1 1.6 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 KRZ99276.1 - 6.7e-23 80.6 0.1 2e-22 79.1 0.1 1.9 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 KRZ99276.1 - 2e-13 50.4 0.5 1.6e-12 47.4 0.3 2.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KRZ99276.1 - 6e-08 33.2 0.1 2.1e-07 31.4 0.1 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase AAA_29 PF13555.6 KRZ99276.1 - 0.0011 18.7 0.1 0.007 16.1 0.0 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain CDC45 PF02724.14 KRZ99276.1 - 0.014 13.7 27.6 0.025 12.9 27.6 1.4 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 KRZ99276.1 - 0.042 13.2 30.1 0.072 12.4 30.1 1.4 1 0 0 1 1 1 0 BUD22 V1R PF03402.14 KRZ99276.1 - 0.15 11.7 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 Vomeronasal organ pheromone receptor family, V1R DUF5308 PF17233.2 KRZ99276.1 - 0.19 11.9 1.1 0.35 11.1 1.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5308) CobT PF06213.12 KRZ99276.1 - 0.4 10.0 38.7 0.8 9.0 38.7 1.5 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Spore_coat_CotO PF14153.6 KRZ99276.1 - 0.84 9.5 30.5 2 8.3 30.5 1.7 1 0 0 1 1 1 0 Spore coat protein CotO CCSAP PF15748.5 KRZ99276.1 - 1.1 9.4 20.7 2.1 8.4 20.7 1.5 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Zip PF02535.22 KRZ99276.1 - 2.9 7.0 12.6 4.6 6.4 12.6 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Paf1 PF03985.13 KRZ99276.1 - 6.3 5.7 40.9 14 4.5 40.9 1.6 1 0 0 1 1 1 0 Paf1 MDM10 PF12519.8 KRZ99276.1 - 9.6 4.9 12.9 17 4.1 12.9 1.4 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Zn_clus PF00172.18 KRZ99278.1 - 4.4e-07 29.9 9.8 7.9e-07 29.1 9.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain N2227 PF07942.12 KRZ99279.1 - 2.1e-80 269.8 0.0 3e-80 269.3 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.6 KRZ99279.1 - 0.00039 20.3 0.0 0.00078 19.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KRZ99279.1 - 0.00065 20.4 0.0 0.0053 17.5 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KRZ99279.1 - 0.0017 19.0 0.0 0.12 13.0 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KRZ99279.1 - 0.034 14.9 0.0 4.8 7.9 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 KRZ99279.1 - 0.12 11.5 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family MFS_1 PF07690.16 KRZ99280.1 - 6.4e-26 91.1 13.8 6.4e-26 91.1 13.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4064 PF13273.6 KRZ99280.1 - 0.29 11.4 3.2 1.2 9.5 2.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) FliE PF02049.18 KRZ99281.1 - 1.3 9.3 4.0 1.3 9.2 1.8 2.2 2 1 0 2 2 2 0 Flagellar hook-basal body complex protein FliE Apt1 PF10351.9 KRZ99281.1 - 1.5 7.6 11.4 2 7.2 11.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SR-25 PF10500.9 KRZ99281.1 - 2.2 7.8 26.1 3.8 7.1 26.1 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF572 PF04502.13 KRZ99281.1 - 3.1 7.3 4.9 4.9 6.7 4.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Git3 PF11710.8 KRZ99282.1 - 6.7e-84 280.7 16.6 1e-83 280.1 16.6 1.3 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 KRZ99282.1 - 7.7e-33 112.4 1.7 2.6e-32 110.7 1.7 2.0 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term Pep1_7 PF17232.2 KRZ99282.1 - 1.3 9.6 3.1 0.44 11.0 0.2 1.7 2 0 0 2 2 2 0 Elicitor peptide 1-7 FMO-like PF00743.19 KRZ99283.1 - 2.2e-23 82.5 0.6 6e-17 61.3 0.3 2.6 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KRZ99283.1 - 6.3e-19 68.3 0.0 2.3e-15 56.7 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KRZ99283.1 - 3.2e-12 46.3 0.0 1.3e-07 31.1 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KRZ99283.1 - 4.2e-12 45.9 0.0 1.5e-09 37.5 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KRZ99283.1 - 4.2e-05 24.0 0.1 0.0028 18.2 0.0 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KRZ99283.1 - 0.00013 21.3 0.0 0.00065 19.1 0.0 2.1 3 0 0 3 3 3 1 FAD binding domain 2-Hacid_dh_C PF02826.19 KRZ99283.1 - 0.00024 20.5 0.0 0.016 14.6 0.0 2.4 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_8 PF13450.6 KRZ99283.1 - 0.0014 18.8 0.0 0.0034 17.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KRZ99283.1 - 0.0098 15.5 0.0 0.43 10.1 0.0 2.9 2 1 1 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.22 KRZ99283.1 - 0.031 13.4 0.9 0.24 10.4 0.0 2.5 3 0 0 3 3 3 0 Glucose inhibited division protein A HI0933_like PF03486.14 KRZ99283.1 - 0.037 12.7 0.2 0.2 10.3 0.0 2.2 3 0 0 3 3 3 0 HI0933-like protein Thi4 PF01946.17 KRZ99283.1 - 0.04 13.2 0.0 0.7 9.1 0.0 2.3 2 0 0 2 2 2 0 Thi4 family TrkA_N PF02254.18 KRZ99283.1 - 0.055 13.7 0.0 3.2 8.0 0.0 2.9 3 0 0 3 3 3 0 TrkA-N domain Shikimate_DH PF01488.20 KRZ99283.1 - 0.072 13.1 0.0 8.7 6.4 0.0 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_oxidored PF12831.7 KRZ99283.1 - 0.078 12.3 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KRZ99283.1 - 0.1 11.6 0.1 0.19 10.8 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_7 PF13241.6 KRZ99283.1 - 0.12 12.8 0.0 16 6.0 0.0 2.8 2 1 0 2 2 2 0 Putative NAD(P)-binding adh_short PF00106.25 KRZ99284.1 - 1.5e-41 142.0 0.0 1.9e-41 141.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KRZ99284.1 - 1.3e-27 96.9 0.0 1.8e-27 96.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KRZ99284.1 - 0.0015 18.4 0.0 0.0026 17.7 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KRZ99284.1 - 0.079 12.4 0.0 0.13 11.7 0.0 1.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KRZ99284.1 - 0.13 11.8 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family 2H-phosphodiest PF08975.10 KRZ99285.1 - 0.043 13.8 0.1 0.11 12.5 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1868) SWC7 PF17330.2 KRZ99285.1 - 0.11 12.6 0.6 3 8.0 0.0 2.3 2 0 0 2 2 2 0 SWR1 chromatin-remodelling complex, sub-unit Swc7 AMP-binding PF00501.28 KRZ99286.1 - 3.3e-64 217.0 0.0 9.1e-64 215.6 0.0 1.6 2 0 0 2 2 2 1 AMP-binding enzyme ABC_tran PF00005.27 KRZ99287.1 - 7.5e-38 130.1 4.7 1.6e-18 67.6 0.0 3.8 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KRZ99287.1 - 6.8e-13 49.1 24.3 5.6e-06 26.4 8.1 4.4 2 2 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KRZ99287.1 - 7.1e-10 38.7 3.1 0.0002 20.9 1.2 4.1 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain ABC_tran_Xtn PF12848.7 KRZ99287.1 - 5.1e-07 29.6 4.0 5.1e-07 29.6 4.0 2.6 2 0 0 2 2 2 1 ABC transporter AAA_28 PF13521.6 KRZ99287.1 - 1.5e-05 25.3 0.1 0.29 11.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KRZ99287.1 - 9.9e-05 22.0 1.9 0.25 11.1 0.3 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KRZ99287.1 - 0.00012 22.3 0.0 0.31 11.3 0.0 3.1 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KRZ99287.1 - 0.0002 21.3 1.1 0.53 10.2 0.0 3.1 3 0 0 3 3 3 2 RsgA GTPase AAA_18 PF13238.6 KRZ99287.1 - 0.0021 18.6 1.0 0.22 12.1 0.2 2.9 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KRZ99287.1 - 0.0063 16.6 3.3 0.078 13.1 0.1 3.3 3 0 0 3 3 2 1 50S ribosome-binding GTPase NACHT PF05729.12 KRZ99287.1 - 0.015 15.2 3.1 2.8 7.8 0.1 2.7 3 0 0 3 3 3 0 NACHT domain AAA_25 PF13481.6 KRZ99287.1 - 0.016 14.8 0.1 1.5 8.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KRZ99287.1 - 0.017 15.5 3.6 4.6 7.6 0.0 3.1 3 1 0 3 3 3 0 AAA ATPase domain AAA PF00004.29 KRZ99287.1 - 0.039 14.4 0.3 1.7 9.1 0.0 3.2 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 KRZ99287.1 - 0.042 14.4 29.7 0.029 14.9 12.9 3.8 4 1 0 4 4 3 0 AAA domain MeaB PF03308.16 KRZ99287.1 - 0.044 12.8 0.2 0.74 8.7 0.1 2.6 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 KRZ99287.1 - 0.046 13.4 6.6 2 8.1 0.6 3.0 3 0 0 3 3 3 0 AAA domain AAA_5 PF07728.14 KRZ99287.1 - 0.15 12.0 1.7 18 5.3 0.1 3.6 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) ATP-synt_ab PF00006.25 KRZ99287.1 - 0.17 11.6 0.6 8.6 5.9 0.0 2.8 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_14 PF13173.6 KRZ99287.1 - 0.19 11.8 3.0 23 5.0 0.0 3.5 3 1 0 3 3 3 0 AAA domain AAA_7 PF12775.7 KRZ99287.1 - 0.23 11.0 1.4 20 4.6 0.0 2.7 2 1 0 2 2 2 0 P-loop containing dynein motor region RNA_helicase PF00910.22 KRZ99287.1 - 0.25 11.7 2.3 13 6.2 0.0 3.4 4 0 0 4 4 3 0 RNA helicase AAA_33 PF13671.6 KRZ99287.1 - 0.92 9.7 2.8 23 5.1 0.5 2.8 2 0 0 2 2 2 0 AAA domain MFS_1 PF07690.16 KRZ99288.1 - 1.1e-28 100.2 21.8 1.1e-28 100.2 21.8 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KRZ99288.1 - 1.1e-08 34.4 1.8 1.1e-08 34.4 1.8 3.2 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 KRZ99288.1 - 7.4e-06 24.7 1.1 1.4e-05 23.7 1.1 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3759 PF12585.8 KRZ99288.1 - 0.2 11.7 0.0 0.59 10.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3759) Aa_trans PF01490.18 KRZ99289.1 - 1.7e-35 122.5 31.4 1.7e-35 122.5 31.4 1.3 2 0 0 2 2 2 1 Transmembrane amino acid transporter protein Bromo_MP PF01573.16 KRZ99289.1 - 0.091 12.1 0.1 0.22 10.9 0.0 1.6 2 0 0 2 2 2 0 Bromovirus movement protein SLATT_5 PF18160.1 KRZ99289.1 - 9.8 5.4 10.6 0.43 9.9 0.1 3.3 4 0 0 4 4 4 0 SMODS and SLOG-associating 2TM effector domain family 5 Pan3_PK PF18101.1 KRZ99290.1 - 4.9e-27 94.6 0.3 1.4e-26 93.1 0.3 1.7 2 0 0 2 2 2 1 Pan3 Pseudokinase domain Pkinase PF00069.25 KRZ99290.1 - 1.9e-06 27.5 0.0 3.1e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain ADK PF00406.22 KRZ99292.1 - 9.1e-45 152.4 0.0 1.3e-44 152.0 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KRZ99292.1 - 7.9e-35 120.2 0.0 1.1e-34 119.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KRZ99292.1 - 2.2e-09 37.9 0.0 3.3e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KRZ99292.1 - 1.2e-05 25.5 0.0 5.4e-05 23.4 0.0 2.0 2 1 0 2 2 2 1 AAA domain Thymidylate_kin PF02223.17 KRZ99292.1 - 0.016 14.9 0.6 2.1 8.0 0.1 2.2 1 1 1 2 2 2 0 Thymidylate kinase SRP54 PF00448.22 KRZ99292.1 - 0.064 12.9 0.0 0.095 12.3 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Methyltr_RsmB-F PF01189.17 KRZ99292.1 - 0.091 12.4 0.0 0.22 11.1 0.0 1.6 2 0 0 2 2 2 0 16S rRNA methyltransferase RsmB/F Ploopntkinase3 PF18751.1 KRZ99292.1 - 0.11 12.5 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 Zeta_toxin PF06414.12 KRZ99292.1 - 0.14 11.4 0.0 0.2 10.9 0.0 1.4 1 1 0 1 1 1 0 Zeta toxin Rotamase PF00639.21 KRZ99293.1 - 4.7e-21 75.6 0.0 7.5e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 KRZ99293.1 - 3.4e-17 63.1 0.0 4.5e-17 62.7 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 KRZ99293.1 - 8.4e-09 35.4 0.4 1.4e-08 34.7 0.4 1.4 1 0 0 1 1 1 1 WW domain Rotamase_2 PF13145.6 KRZ99293.1 - 9.2e-07 29.7 0.0 5.4e-06 27.3 0.0 1.9 1 1 1 2 2 2 1 PPIC-type PPIASE domain Peptidase_M1 PF01433.20 KRZ99294.1 - 1.1e-85 286.6 1.1 1.7e-85 286.0 1.1 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 KRZ99294.1 - 3.1e-84 283.2 0.3 6.9e-83 278.8 0.1 2.2 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 KRZ99294.1 - 6.9e-57 192.6 2.3 1e-56 192.1 1.0 1.9 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain RE_Bsp6I PF09504.10 KRZ99294.1 - 0.054 13.1 2.8 1.1 8.8 0.3 2.5 2 0 0 2 2 2 0 Bsp6I restriction endonuclease ATP-synt_ab PF00006.25 KRZ99297.1 - 6.9e-71 238.3 0.0 9.9e-71 237.8 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 KRZ99297.1 - 1.6e-46 157.8 0.8 2.6e-46 157.1 0.8 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 KRZ99297.1 - 1.6e-05 25.3 0.2 4.9e-05 23.8 0.2 1.9 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain TetR_C_24 PF17932.1 KRZ99297.1 - 0.18 12.1 0.1 1.6 9.0 0.1 2.2 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain PhoLip_ATPase_C PF16212.5 KRZ99300.1 - 4.3e-47 161.0 18.7 4.3e-47 161.0 18.7 2.5 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KRZ99300.1 - 1.6e-18 66.1 5.3 5.1e-18 64.5 5.3 1.9 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 KRZ99300.1 - 1.7e-11 44.0 0.0 1.7e-11 44.0 0.0 2.4 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 KRZ99300.1 - 1.8e-11 44.8 0.3 0.00027 21.3 0.0 3.8 4 0 0 4 4 4 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KRZ99300.1 - 6.9e-09 35.7 0.1 1.1e-07 31.8 0.0 2.7 3 0 0 3 3 3 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KRZ99300.1 - 0.0012 18.6 0.2 0.0045 16.8 0.2 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Prot_ATP_ID_OB PF16450.5 KRZ99300.1 - 0.035 14.1 0.1 0.089 12.8 0.1 1.6 1 0 0 1 1 1 0 Proteasomal ATPase OB C-terminal domain DUF2269 PF10027.9 KRZ99300.1 - 0.039 14.0 2.3 0.098 12.7 0.4 2.7 4 0 0 4 4 4 0 Predicted integral membrane protein (DUF2269) Abhydrolase_1 PF00561.20 KRZ99301.1 - 4.6e-16 59.2 0.0 3.5e-15 56.4 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KRZ99301.1 - 9.4e-15 55.8 0.0 1.7e-14 55.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DSPc PF00782.20 KRZ99301.1 - 7.2e-12 45.3 0.0 2.6e-11 43.5 0.0 2.0 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Hydrolase_4 PF12146.8 KRZ99301.1 - 1.5e-10 40.8 0.0 9.3e-10 38.2 0.0 2.2 2 1 0 2 2 2 1 Serine aminopeptidase, S33 LIDHydrolase PF10230.9 KRZ99301.1 - 2.4e-09 37.2 0.0 4.1e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Ser_hydrolase PF06821.13 KRZ99301.1 - 9.2e-06 25.6 0.0 2e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Serine hydrolase PGAP1 PF07819.13 KRZ99301.1 - 1.2e-05 25.2 0.6 3.9e-05 23.5 0.2 2.1 2 1 0 2 2 2 1 PGAP1-like protein Abhydrolase_2 PF02230.16 KRZ99301.1 - 1.8e-05 24.6 0.2 0.13 12.0 0.0 3.4 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Thioesterase PF00975.20 KRZ99301.1 - 0.00013 22.2 0.0 0.014 15.5 0.0 2.3 1 1 1 2 2 2 1 Thioesterase domain Chlorophyllase2 PF12740.7 KRZ99301.1 - 0.00016 20.6 0.5 0.00062 18.8 0.1 2.1 2 0 0 2 2 2 1 Chlorophyllase enzyme DSPn PF14671.6 KRZ99301.1 - 0.00033 21.1 0.0 0.00069 20.1 0.0 1.5 1 0 0 1 1 1 1 Dual specificity protein phosphatase, N-terminal half Y_phosphatase PF00102.27 KRZ99301.1 - 0.0031 17.1 0.0 0.0066 16.0 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Esterase PF00756.20 KRZ99301.1 - 0.0036 17.0 0.0 0.006 16.3 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.13 KRZ99301.1 - 0.0039 17.1 0.0 0.0068 16.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 KRZ99301.1 - 0.0093 15.7 0.1 0.099 12.4 0.0 2.4 3 0 0 3 3 3 1 Alpha/beta hydrolase family DUF676 PF05057.14 KRZ99301.1 - 0.0098 15.4 0.5 0.035 13.6 0.3 2.0 2 1 0 2 2 2 1 Putative serine esterase (DUF676) DUF900 PF05990.12 KRZ99301.1 - 0.011 15.3 0.1 0.16 11.4 0.0 2.6 3 0 0 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF900) DUF1057 PF06342.12 KRZ99301.1 - 0.013 14.5 0.0 0.024 13.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Y_phosphatase3 PF13350.6 KRZ99301.1 - 0.022 14.8 0.0 0.47 10.4 0.0 2.2 2 0 0 2 2 2 0 Tyrosine phosphatase family Peptidase_S9 PF00326.21 KRZ99301.1 - 0.047 13.1 0.0 4.3 6.8 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family PTPlike_phytase PF14566.6 KRZ99301.1 - 0.071 13.2 0.0 0.35 11.0 0.0 2.1 2 0 0 2 2 2 0 Inositol hexakisphosphate SPX PF03105.19 KRZ99302.1 - 3.3e-50 172.1 22.2 4.3e-50 171.8 22.2 1.1 1 0 0 1 1 1 1 SPX domain EXS PF03124.14 KRZ99302.1 - 1.1e-27 97.2 14.1 1.6e-27 96.8 14.1 1.2 1 0 0 1 1 1 1 EXS family SDA1 PF05285.12 KRZ99303.1 - 2 7.7 38.0 2.3 7.6 38.0 1.1 1 0 0 1 1 1 0 SDA1 eIF-3c_N PF05470.12 KRZ99303.1 - 2.7 6.2 19.3 3.7 5.8 19.3 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus BUD22 PF09073.10 KRZ99303.1 - 3.8 6.7 43.4 4.8 6.4 43.4 1.1 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 KRZ99303.1 - 7.4 4.7 29.8 8.4 4.5 29.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 KRZ99303.1 - 8.4 5.0 19.5 8.4 5.0 19.5 1.1 1 0 0 1 1 1 0 Presenilin Band_3_cyto PF07565.13 KRZ99303.1 - 9 6.0 12.0 10 5.8 12.0 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Abhydrolase_6 PF12697.7 KRZ99304.1 - 5.1e-15 56.7 0.0 6.7e-15 56.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KRZ99304.1 - 2.6e-09 36.7 0.0 1.1e-08 34.6 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KRZ99304.1 - 2.7e-06 27.2 0.3 4.8e-06 26.4 0.3 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 KRZ99304.1 - 1.3e-05 25.0 0.0 2.1e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 KRZ99304.1 - 0.00016 21.2 0.0 0.00029 20.4 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family LCAT PF02450.15 KRZ99304.1 - 0.0031 16.8 0.0 0.0051 16.0 0.0 1.3 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF2920 PF11144.8 KRZ99304.1 - 0.05 12.8 0.1 0.14 11.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2920) PGAP1 PF07819.13 KRZ99304.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_2 PF02230.16 KRZ99304.1 - 0.12 12.1 0.0 1.7 8.4 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.7 KRZ99304.1 - 0.13 12.0 0.0 0.3 10.8 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.7 KRZ99305.1 - 1.6e-11 45.3 0.0 2e-11 44.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KRZ99305.1 - 6.9e-09 35.3 0.0 9e-09 34.9 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 KRZ99305.1 - 0.00062 19.5 0.0 0.0012 18.6 0.0 1.4 1 1 0 1 1 1 1 Putative esterase DUF2920 PF11144.8 KRZ99305.1 - 0.0035 16.6 0.0 0.0048 16.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2920) Peptidase_S9 PF00326.21 KRZ99305.1 - 0.0041 16.6 0.0 0.0068 15.9 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 KRZ99305.1 - 0.011 15.6 0.0 0.17 11.7 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase PGAP1 PF07819.13 KRZ99305.1 - 0.018 14.8 0.0 0.031 14.0 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein LIDHydrolase PF10230.9 KRZ99305.1 - 0.021 14.4 0.8 0.036 13.6 0.0 1.8 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase DUF4284 PF14112.6 KRZ99305.1 - 0.025 15.5 1.9 0.026 15.4 0.5 1.8 2 0 0 2 2 2 0 Immunity protein 22 Lipase_3 PF01764.25 KRZ99305.1 - 0.072 13.0 0.3 0.16 11.8 0.3 1.7 1 1 0 1 1 1 0 Lipase (class 3) Pantoate_ligase PF02569.15 KRZ99306.1 - 5.4e-84 281.5 0.0 6.1e-84 281.4 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase Baculo_p24 PF05073.12 KRZ99306.1 - 0.059 13.2 0.1 0.093 12.5 0.1 1.3 1 0 0 1 1 1 0 Baculovirus P24 capsid protein Catalase-rel PF06628.12 KRZ99306.1 - 0.14 12.3 0.0 1.3 9.3 0.0 2.3 2 0 0 2 2 2 0 Catalase-related immune-responsive CTP_transf_like PF01467.26 KRZ99306.1 - 0.16 12.2 0.0 0.64 10.2 0.0 1.9 1 1 1 2 2 2 0 Cytidylyltransferase-like HA2 PF04408.23 KRZ99307.1 - 8.8e-23 80.7 0.2 1.7e-21 76.5 0.0 3.1 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KRZ99307.1 - 3.7e-19 68.9 0.1 1.1e-18 67.3 0.1 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KRZ99307.1 - 1.5e-14 54.2 0.2 5.3e-14 52.5 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KRZ99307.1 - 1.1e-06 28.6 0.1 2.4e-06 27.4 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KRZ99307.1 - 0.00012 22.4 0.5 0.00032 21.0 0.1 1.9 2 0 0 2 2 1 1 AAA domain DUF2075 PF09848.9 KRZ99307.1 - 0.0037 16.6 0.0 0.011 14.9 0.0 1.9 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) T2SSE PF00437.20 KRZ99307.1 - 0.023 13.8 0.0 0.063 12.3 0.0 1.7 1 0 0 1 1 1 0 Type II/IV secretion system protein Flavi_DEAD PF07652.14 KRZ99307.1 - 0.033 14.2 0.0 0.082 12.9 0.0 1.7 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_19 PF13245.6 KRZ99307.1 - 0.04 14.2 1.8 0.13 12.6 0.1 2.7 4 0 0 4 4 4 0 AAA domain AAA_30 PF13604.6 KRZ99307.1 - 0.066 12.9 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 KRZ99307.1 - 0.1 11.9 0.1 0.23 10.8 0.1 1.5 1 0 0 1 1 1 0 KaiC AAA_18 PF13238.6 KRZ99307.1 - 0.61 10.6 4.3 1.3 9.6 0.0 3.4 3 0 0 3 3 3 0 AAA domain Nup54 PF13874.6 KRZ99309.1 - 1.6e-35 122.2 1.3 3.8e-35 121.0 0.2 2.1 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.6 KRZ99309.1 - 1.7e-25 89.7 153.6 1.6e-09 38.4 36.6 5.4 1 1 4 5 5 5 5 Nucleoporin FG repeat region CX9C PF16860.5 KRZ99310.1 - 0.0051 16.8 2.1 0.0051 16.8 2.1 2.2 2 0 0 2 2 2 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, HALZ PF02183.18 KRZ99310.1 - 0.025 14.8 0.2 0.062 13.5 0.2 1.7 1 0 0 1 1 1 0 Homeobox associated leucine zipper CHCH PF06747.13 KRZ99310.1 - 0.027 14.6 14.6 0.037 14.2 4.2 2.6 3 0 0 3 3 3 0 CHCH domain Colipase-like PF15083.6 KRZ99310.1 - 0.067 13.3 7.5 0.1 12.7 7.5 1.3 1 0 0 1 1 1 0 Colipase-like COX6B PF02297.17 KRZ99310.1 - 1 9.7 10.1 2.1 8.6 3.6 2.3 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb COG2 PF06148.11 KRZ99311.1 - 3.9e-18 65.8 6.7 3.9e-18 65.8 6.7 1.6 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 PA26 PF04636.13 KRZ99311.1 - 0.0041 16.1 0.1 0.0053 15.7 0.1 1.3 1 0 0 1 1 1 1 PA26 p53-induced protein (sestrin) Vps51 PF08700.11 KRZ99311.1 - 0.0093 16.0 0.5 0.0093 16.0 0.5 2.4 3 0 0 3 3 3 1 Vps51/Vps67 HMG_box PF00505.19 KRZ99312.1 - 2.3e-17 63.2 0.3 6.1e-17 61.8 0.3 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KRZ99312.1 - 2.1e-07 31.4 0.1 2.1e-07 31.4 0.1 2.1 3 0 0 3 3 3 1 HMG-box domain COX4 PF02936.14 KRZ99312.1 - 0.018 15.1 2.6 0.023 14.7 0.7 2.1 1 1 0 1 1 1 0 Cytochrome c oxidase subunit IV FAM60A PF15396.6 KRZ99312.1 - 0.2 11.6 5.6 0.1 12.6 0.9 2.2 2 0 0 2 2 2 0 Protein Family FAM60A CIAPIN1 PF05093.13 KRZ99313.1 - 1.2e-38 131.6 6.1 1.2e-38 131.6 6.1 2.7 2 1 0 2 2 2 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DRE2_N PF16803.5 KRZ99313.1 - 2.1e-32 112.2 0.1 3.9e-32 111.3 0.1 1.5 1 0 0 1 1 1 1 Fe-S cluster assembly protein DRE2 N-terminus PEP-utilisers_N PF05524.13 KRZ99313.1 - 0.0059 16.8 0.0 0.014 15.6 0.0 1.6 1 0 0 1 1 1 1 PEP-utilising enzyme, N-terminal PH_15 PF17339.2 KRZ99313.1 - 0.0085 16.0 0.1 0.018 15.0 0.1 1.5 1 0 0 1 1 1 1 PH domain Mannosidase_ig PF17786.1 KRZ99314.1 - 9.1e-16 58.3 0.3 2.6e-15 56.8 0.3 1.9 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 KRZ99314.1 - 5.4e-13 49.6 0.3 2.4e-12 47.5 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.18 KRZ99314.1 - 0.0048 16.8 0.0 0.013 15.4 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain DUF5001 PF16392.5 KRZ99314.1 - 0.021 14.7 1.0 0.4 10.6 0.2 3.3 4 0 0 4 4 4 0 Ig-like domain Mito_carr PF00153.27 KRZ99316.1 - 1.1e-30 105.4 10.1 1.9e-09 37.3 0.1 5.0 3 2 0 3 3 3 3 Mitochondrial carrier protein Acetyltransf_13 PF13880.6 KRZ99317.1 - 1.6e-18 66.4 0.0 3e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.6 KRZ99317.1 - 1.4e-11 44.0 0.6 2.3e-11 43.3 0.6 1.4 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_7 PF13508.7 KRZ99317.1 - 0.00031 21.1 0.0 0.00069 20.0 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KRZ99317.1 - 0.00076 19.7 0.0 0.0013 19.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family zf-Mss51 PF13824.6 KRZ99317.1 - 0.058 13.5 0.1 0.13 12.3 0.1 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Acetyltransf_10 PF13673.7 KRZ99317.1 - 0.059 13.3 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain QRPTase_C PF01729.19 KRZ99318.1 - 9.9e-57 191.4 0.0 1.4e-56 190.9 0.0 1.2 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 KRZ99318.1 - 5.6e-17 61.6 0.5 2e-16 59.8 0.2 2.1 2 1 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain FMN_dh PF01070.18 KRZ99318.1 - 0.1 11.6 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 FMN-dependent dehydrogenase ANAPC10 PF03256.16 KRZ99319.1 - 1.1e-41 142.5 0.2 9.3e-31 106.9 0.0 2.1 1 1 1 2 2 2 2 Anaphase-promoting complex, subunit 10 (APC10) PITH PF06201.13 KRZ99319.1 - 0.014 15.6 0.1 0.029 14.6 0.1 1.6 1 0 0 1 1 1 0 PITH domain SMI1_KNR4 PF09346.10 KRZ99320.1 - 1.3e-34 119.5 0.0 1.3e-34 119.5 0.0 2.5 2 1 0 2 2 2 1 SMI1 / KNR4 family (SUKH-1) GCS PF03074.16 KRZ99321.1 - 1.7e-143 478.4 0.0 2.3e-143 478.0 0.0 1.2 1 0 0 1 1 1 1 Glutamate-cysteine ligase CBFB_NFYA PF02045.15 KRZ99323.1 - 9.4e-29 99.8 7.3 2.1e-28 98.7 7.3 1.6 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Cse1 PF08506.10 KRZ99324.1 - 3.7e-160 532.8 18.4 7.9e-160 531.7 18.4 1.6 1 0 0 1 1 1 1 Cse1 CAS_CSE1 PF03378.15 KRZ99324.1 - 1.4e-111 373.2 8.3 1.4e-111 373.2 8.3 2.8 2 1 1 3 3 3 1 CAS/CSE protein, C-terminus IBN_N PF03810.19 KRZ99324.1 - 1.4e-14 53.7 2.9 3e-14 52.7 0.1 3.3 3 0 0 3 3 3 1 Importin-beta N-terminal domain EamA PF00892.20 KRZ99325.1 - 0.01 16.0 31.8 0.016 15.4 12.0 2.2 2 0 0 2 2 2 0 EamA-like transporter family GATase_6 PF13522.6 KRZ99326.1 - 1.1e-12 48.3 0.0 2.2e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KRZ99326.1 - 1.4e-10 41.1 0.0 2.6e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 KRZ99326.1 - 1.6e-07 30.9 0.0 3e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain DUF1400 PF07176.11 KRZ99326.1 - 0.18 12.1 0.0 0.52 10.6 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1400) IU_nuc_hydro PF01156.19 KRZ99327.1 - 1.5e-70 238.2 0.0 1.7e-70 238.0 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase His_Phos_1 PF00300.22 KRZ99328.1 - 2.7e-34 118.6 0.0 3.7e-34 118.1 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) eIF3_subunit PF08597.10 KRZ99329.1 - 0.17 11.8 1.6 0.19 11.6 1.6 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Lectin_leg-like PF03388.13 KRZ99330.1 - 1.9e-57 194.2 0.4 2.5e-57 193.9 0.4 1.1 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 KRZ99330.1 - 8.7e-07 29.2 3.3 1.3e-06 28.6 3.3 1.2 1 0 0 1 1 1 1 Bacterial lectin Lectin_legB PF00139.19 KRZ99330.1 - 6.2e-05 22.7 0.1 0.0011 18.6 0.1 2.1 2 0 0 2 2 2 1 Legume lectin domain Pho86 PF11124.8 KRZ99331.1 - 7.3e-108 360.4 2.8 8.3e-108 360.3 2.8 1.0 1 0 0 1 1 1 1 Inorganic phosphate transporter Pho86 PGBA_N PF15436.6 KRZ99331.1 - 0.04 13.5 0.1 0.21 11.2 0.0 1.9 2 0 0 2 2 2 0 Plasminogen-binding protein pgbA N-terminal Ndr PF03096.14 KRZ99331.1 - 0.051 12.3 0.0 0.18 10.5 0.0 1.7 2 0 0 2 2 2 0 Ndr family CUE PF02845.16 KRZ99332.1 - 2.9e-05 23.7 0.4 8.1e-05 22.2 0.4 1.9 1 0 0 1 1 1 1 CUE domain Adap_comp_sub PF00928.21 KRZ99333.1 - 2.5e-75 253.3 0.5 3.1e-75 253.0 0.5 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KRZ99333.1 - 4.1e-06 26.8 0.2 9.9e-06 25.5 0.2 1.7 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Pribosyl_synth PF14572.6 KRZ99334.1 - 1.7e-39 135.8 0.5 3.4e-39 134.8 0.5 1.5 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 KRZ99334.1 - 3.2e-33 114.1 0.0 8.6e-33 112.7 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 KRZ99334.1 - 1.5e-14 53.8 0.2 2.9e-14 52.9 0.2 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KRZ99334.1 - 0.052 13.0 0.1 0.11 12.0 0.1 1.5 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase ELFV_dehydrog PF00208.21 KRZ99335.1 - 2.2e-69 233.9 0.0 3.9e-69 233.1 0.0 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 KRZ99335.1 - 2.3e-19 68.5 0.1 1.4e-18 66.0 0.1 1.9 1 1 0 1 1 1 1 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.18 KRZ99335.1 - 0.011 15.6 0.0 0.07 13.0 0.0 2.3 2 0 0 2 2 2 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain CPSF_A PF03178.15 KRZ99336.1 - 0.011 15.1 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 0 CPSF A subunit region WD40 PF00400.32 KRZ99336.1 - 0.029 15.2 10.0 0.43 11.5 0.3 4.6 5 0 0 5 5 5 0 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KRZ99336.1 - 0.038 13.0 0.0 0.11 11.4 0.0 1.7 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein RNase_PH_C PF03725.15 KRZ99336.1 - 0.14 12.2 0.0 0.5 10.4 0.0 1.9 2 0 0 2 2 2 0 3' exoribonuclease family, domain 2 WH2 PF02205.20 KRZ99337.1 - 1.1e-13 50.5 0.1 3.9e-10 39.2 0.4 2.8 2 0 0 2 2 2 2 WH2 motif Glycos_transf_4 PF00953.21 KRZ99338.1 - 5.5e-31 107.7 12.4 5.5e-31 107.7 12.4 2.6 3 1 0 3 3 3 1 Glycosyl transferase family 4 WD40 PF00400.32 KRZ99339.1 - 6.9e-19 67.8 10.2 0.00046 20.9 0.0 5.5 5 1 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KRZ99339.1 - 1.2e-08 35.1 2.2 0.17 12.2 0.0 4.0 2 2 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain TIMP PF00965.17 KRZ99339.1 - 0.021 14.7 0.1 0.046 13.5 0.1 1.5 2 0 0 2 2 2 0 Tissue inhibitor of metalloproteinase DUF4033 PF13225.6 KRZ99339.1 - 0.14 12.2 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4033) Herpes_gE PF02480.16 KRZ99340.1 - 0.075 11.8 0.5 0.18 10.5 0.2 1.7 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E SPT6_acidic PF14632.6 KRZ99340.1 - 0.2 12.3 18.3 0.46 11.1 18.3 1.6 1 0 0 1 1 1 0 Acidic N-terminal SPT6 TauD PF02668.16 KRZ99341.1 - 3.1e-59 200.9 1.1 4e-59 200.6 1.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF1749 PF08538.10 KRZ99342.1 - 1.9e-90 303.0 0.0 2.1e-90 302.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) DUF900 PF05990.12 KRZ99342.1 - 0.00014 21.5 0.0 0.00021 20.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) RA PF00788.23 KRZ99343.1 - 1.2e-11 45.1 0.0 4.3e-11 43.3 0.0 1.8 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain SAM_2 PF07647.17 KRZ99343.1 - 3.3e-09 36.7 0.0 8.8e-09 35.4 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KRZ99343.1 - 5.7e-07 29.9 0.0 2.6e-06 27.8 0.0 2.1 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) SAM_Ste50p PF09235.10 KRZ99343.1 - 0.019 15.2 0.0 0.039 14.2 0.0 1.5 1 0 0 1 1 1 0 Ste50p, sterile alpha motif Ribosomal_L11_N PF03946.14 KRZ99344.1 - 2.6e-21 75.2 0.4 5.7e-21 74.1 0.2 1.7 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 KRZ99344.1 - 9.4e-17 61.3 1.2 1.5e-16 60.7 0.2 1.7 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain Syntaxin-6_N PF09177.11 KRZ99345.1 - 0.03 14.9 0.5 0.44 11.1 0.0 2.7 3 0 0 3 3 3 0 Syntaxin 6, N-terminal ACBP PF00887.19 KRZ99346.1 - 3.7e-09 36.7 0.2 9.6e-09 35.3 0.2 1.8 1 0 0 1 1 1 1 Acyl CoA binding protein WD40 PF00400.32 KRZ99347.1 - 6.7e-10 39.4 18.3 1.1 10.2 0.2 9.0 9 1 0 9 9 9 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KRZ99347.1 - 5.6e-09 36.2 3.3 0.27 11.6 0.1 6.9 2 2 5 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain DUF1921 PF09081.10 KRZ99347.1 - 0.085 13.1 0.1 0.33 11.2 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1921) Glyco_hydro_76 PF03663.14 KRZ99348.1 - 3.9e-44 151.7 9.2 5.5e-44 151.2 9.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 KRZ99348.1 - 0.00055 19.1 4.8 0.81 8.7 0.6 3.1 1 1 2 3 3 3 2 Glycosyl Hydrolase Family 88 Glyco_hydro_127 PF07944.12 KRZ99348.1 - 0.00061 18.4 0.3 0.21 10.0 0.0 2.1 2 0 0 2 2 2 2 Beta-L-arabinofuranosidase, GH127 GlcNAc_2-epim PF07221.11 KRZ99348.1 - 0.0011 18.3 0.2 0.068 12.4 0.1 2.7 2 1 1 3 3 3 2 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) C5-epim_C PF06662.13 KRZ99348.1 - 0.0026 17.3 0.1 0.0095 15.5 0.0 2.0 2 0 0 2 2 2 1 D-glucuronyl C5-epimerase C-terminus Sterol_MT_C PF08498.10 KRZ99349.1 - 6.1e-28 96.9 0.2 9.7e-28 96.3 0.2 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 KRZ99349.1 - 2.5e-18 66.5 0.0 5e-18 65.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KRZ99349.1 - 3e-17 63.1 0.0 6.5e-17 62.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KRZ99349.1 - 2.2e-16 60.0 0.2 4.7e-16 59.0 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 KRZ99349.1 - 3.9e-12 46.0 0.7 5.3e-12 45.6 0.7 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 KRZ99349.1 - 1.5e-11 44.9 0.0 3.4e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KRZ99349.1 - 7.2e-11 42.2 0.0 1.1e-10 41.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KRZ99349.1 - 3.1e-07 30.0 0.0 4.9e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_15 PF09445.10 KRZ99349.1 - 5.7e-05 22.7 0.1 9.2e-05 22.1 0.1 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PrmA PF06325.13 KRZ99349.1 - 0.00024 20.6 0.0 0.00064 19.2 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KRZ99349.1 - 0.0012 18.5 0.0 0.0024 17.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 KRZ99349.1 - 0.0013 18.6 0.0 0.0021 17.9 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 KRZ99349.1 - 0.0017 18.4 0.1 0.0033 17.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain RrnaAD PF00398.20 KRZ99349.1 - 0.0048 16.0 0.0 0.0086 15.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase UPF0020 PF01170.18 KRZ99349.1 - 0.14 11.8 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Cnd3 PF12719.7 KRZ99350.1 - 7.6e-100 333.9 1.6 7.6e-100 333.9 1.6 2.5 3 1 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 KRZ99350.1 - 2.3e-09 37.5 0.4 3.2e-06 27.4 0.2 3.9 3 1 2 5 5 5 2 HEAT repeats HEAT PF02985.22 KRZ99350.1 - 1.3e-06 28.2 1.8 1.1 9.7 0.1 6.0 5 0 0 5 5 5 2 HEAT repeat Vac14_Fab1_bd PF12755.7 KRZ99350.1 - 0.034 14.7 0.1 0.23 12.1 0.1 2.5 1 0 0 1 1 1 0 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 KRZ99350.1 - 0.038 14.5 0.3 1.3e+02 3.2 0.1 4.1 4 0 0 4 4 4 0 HEAT-like repeat ER PF01133.17 KRZ99350.1 - 0.65 10.0 7.1 0.33 11.0 1.0 3.3 3 0 0 3 3 3 0 Enhancer of rudimentary DUF1664 PF07889.12 KRZ99350.1 - 5.5 7.0 8.0 36 4.4 7.9 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Mak10 PF04112.13 KRZ99351.1 - 4.8e-44 149.8 0.0 8.7e-44 149.0 0.0 1.4 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase zf-H3C2 PF16721.5 KRZ99351.1 - 0.074 13.4 0.7 0.17 12.3 0.1 2.0 2 0 0 2 2 2 0 Zinc-finger like, probable DNA-binding HMG_box PF00505.19 KRZ99352.1 - 1.2e-25 89.7 0.7 1.2e-25 89.7 0.7 1.5 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KRZ99352.1 - 4.9e-18 65.5 0.4 7.8e-18 64.8 0.4 1.3 1 0 0 1 1 1 1 HMG-box domain CHDNT PF08073.12 KRZ99352.1 - 0.0015 18.5 0.0 0.0023 17.8 0.0 1.3 1 0 0 1 1 1 1 CHDNT (NUC034) domain Ccdc124 PF06244.12 KRZ99352.1 - 0.0022 18.5 3.3 0.0025 18.4 0.0 2.0 1 1 1 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 YABBY PF04690.13 KRZ99352.1 - 0.14 12.7 1.0 0.17 12.4 0.3 1.5 1 1 1 2 2 2 0 YABBY protein AAA_5 PF07728.14 KRZ99354.1 - 2.4e-122 403.3 0.5 3.1e-20 72.6 0.0 9.6 9 0 0 9 9 9 9 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 KRZ99354.1 - 1.4e-51 173.2 4.3 1.1e-19 70.5 0.0 5.8 5 0 0 5 5 4 3 Midasin AAA lid domain AAA_lid_5 PF17865.1 KRZ99354.1 - 3.7e-32 110.5 0.1 1.8e-29 101.9 0.0 3.7 3 0 0 3 3 2 1 Midasin AAA lid domain AAA_3 PF07726.11 KRZ99354.1 - 8.6e-31 106.5 0.0 3.4e-09 36.7 0.0 8.1 8 0 0 8 8 8 4 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KRZ99354.1 - 1.6e-29 102.7 6.5 3.6e-06 26.6 0.0 6.8 7 0 0 7 7 7 5 P-loop containing dynein motor region AAA PF00004.29 KRZ99354.1 - 1.8e-29 102.8 0.2 0.00012 22.5 0.0 7.2 6 0 0 6 6 6 5 ATPase family associated with various cellular activities (AAA) Dynein_heavy PF03028.15 KRZ99354.1 - 2.2e-22 79.4 0.1 9.7e-06 25.7 0.0 7.7 9 0 0 9 9 6 5 Dynein heavy chain region D6 P-loop domain AAA_16 PF13191.6 KRZ99354.1 - 3.4e-22 79.6 3.8 0.0048 17.3 0.3 8.1 6 2 0 6 6 6 5 AAA ATPase domain AAA_6 PF12774.7 KRZ99354.1 - 1.7e-21 76.6 0.3 0.007 15.4 0.0 10.0 10 1 0 10 10 10 4 Hydrolytic ATP binding site of dynein motor region Sigma54_activat PF00158.26 KRZ99354.1 - 2.3e-20 73.0 0.9 3.6e-05 23.5 0.0 6.1 6 0 0 6 6 5 5 Sigma-54 interaction domain AAA_22 PF13401.6 KRZ99354.1 - 5.8e-19 68.7 0.1 0.0092 16.3 0.0 7.5 7 0 0 7 7 6 4 AAA domain TsaE PF02367.17 KRZ99354.1 - 4.2e-18 65.5 1.4 0.04 13.9 0.2 6.8 6 0 0 6 6 6 4 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 KRZ99354.1 - 2.5e-16 60.0 0.6 0.0095 15.7 0.0 7.2 7 1 0 7 7 6 4 AAA domain AAA_14 PF13173.6 KRZ99354.1 - 5.4e-16 58.8 2.5 0.021 14.9 0.0 8.5 9 0 0 9 9 8 3 AAA domain T2SSE PF00437.20 KRZ99354.1 - 1.2e-13 50.7 3.0 0.039 13.0 0.0 6.3 6 0 0 6 6 6 3 Type II/IV secretion system protein Sigma54_activ_2 PF14532.6 KRZ99354.1 - 1.9e-13 50.7 1.3 0.17 12.0 0.0 6.3 5 0 0 5 5 5 3 Sigma-54 interaction domain Zeta_toxin PF06414.12 KRZ99354.1 - 1.2e-11 44.3 6.5 0.13 11.5 0.0 8.0 8 0 0 8 8 8 3 Zeta toxin AAA_18 PF13238.6 KRZ99354.1 - 2e-11 44.5 19.9 0.018 15.5 0.1 9.4 8 1 0 8 8 7 3 AAA domain RNA_helicase PF00910.22 KRZ99354.1 - 2.6e-11 43.8 8.3 0.54 10.7 0.0 8.5 8 1 0 8 8 7 3 RNA helicase ABC_tran PF00005.27 KRZ99354.1 - 5.7e-11 43.1 17.8 0.0062 17.1 0.0 7.1 7 0 0 7 7 6 3 ABC transporter Rad17 PF03215.15 KRZ99354.1 - 1.2e-10 41.6 0.6 0.033 14.1 0.1 6.4 6 0 0 6 6 6 1 Rad17 P-loop domain AAA_33 PF13671.6 KRZ99354.1 - 1.5e-10 41.4 0.1 0.07 13.3 0.0 6.1 6 0 0 6 6 6 2 AAA domain RuvB_N PF05496.12 KRZ99354.1 - 5.4e-10 39.2 3.5 0.19 11.5 0.0 6.7 7 0 0 7 7 7 3 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 KRZ99354.1 - 5.5e-09 35.6 2.0 0.12 11.5 0.1 5.4 5 0 0 5 5 5 2 Protein of unknown function (DUF815) AAA_19 PF13245.6 KRZ99354.1 - 1.7e-08 34.9 1.7 0.58 10.5 0.0 6.4 6 0 0 6 6 5 1 AAA domain Mg_chelatase PF01078.21 KRZ99354.1 - 1.9e-08 34.0 0.7 7.2 5.9 0.0 8.8 10 0 0 10 10 10 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KRZ99354.1 - 2.1e-08 34.1 1.4 0.31 10.8 0.0 6.3 7 0 0 7 7 6 2 IstB-like ATP binding protein RsgA_GTPase PF03193.16 KRZ99354.1 - 3.7e-08 33.5 13.7 0.0061 16.5 0.0 6.0 6 0 0 6 6 5 2 RsgA GTPase PduV-EutP PF10662.9 KRZ99354.1 - 6.2e-08 32.5 5.3 0.24 11.1 0.1 5.8 6 0 0 6 6 6 2 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.6 KRZ99354.1 - 9.6e-08 31.8 0.9 0.11 12.1 0.0 5.6 6 0 0 6 6 5 1 AAA domain Bac_DnaA PF00308.18 KRZ99354.1 - 8.5e-07 29.0 1.5 0.25 11.1 0.0 5.2 5 0 0 5 5 4 1 Bacterial dnaA protein AAA_29 PF13555.6 KRZ99354.1 - 1.7e-06 27.7 0.7 5.2 6.9 0.0 6.1 6 0 0 6 6 6 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KRZ99354.1 - 3.1e-06 27.2 4.8 9.5 6.3 0.0 6.8 6 0 0 6 6 6 0 50S ribosome-binding GTPase NACHT PF05729.12 KRZ99354.1 - 3.7e-06 27.0 9.7 1.6 8.6 0.1 6.0 6 0 0 6 6 4 2 NACHT domain TniB PF05621.11 KRZ99354.1 - 1e-05 25.0 1.8 1.9 7.8 0.0 5.5 6 0 0 6 6 5 1 Bacterial TniB protein VWA PF00092.28 KRZ99354.1 - 1.1e-05 25.7 0.7 1.1e-05 25.7 0.7 3.0 2 1 1 3 3 3 1 von Willebrand factor type A domain KAP_NTPase PF07693.14 KRZ99354.1 - 3.8e-05 23.1 0.7 0.068 12.4 0.0 4.5 5 0 0 5 5 4 1 KAP family P-loop domain SRP54 PF00448.22 KRZ99354.1 - 0.00012 21.8 7.7 0.47 10.1 0.4 4.8 5 0 0 5 5 4 1 SRP54-type protein, GTPase domain Roc PF08477.13 KRZ99354.1 - 0.00014 22.1 6.1 9.8 6.4 0.1 6.3 6 0 0 6 6 6 0 Ras of Complex, Roc, domain of DAPkinase NTPase_1 PF03266.15 KRZ99354.1 - 0.00017 21.6 5.2 1.6 8.6 0.3 5.5 5 0 0 5 5 5 1 NTPase AAA_28 PF13521.6 KRZ99354.1 - 0.00026 21.3 9.4 2.2 8.5 0.0 6.1 6 0 0 6 6 5 1 AAA domain ATP-synt_ab PF00006.25 KRZ99354.1 - 0.00029 20.6 0.7 6.9 6.3 0.0 4.8 5 1 1 6 6 6 0 ATP synthase alpha/beta family, nucleotide-binding domain PIF1 PF05970.14 KRZ99354.1 - 0.00094 18.4 3.9 0.52 9.4 0.0 5.1 5 0 0 5 5 5 1 PIF1-like helicase PhoH PF02562.16 KRZ99354.1 - 0.00099 18.6 4.5 1.9 7.9 0.2 4.2 4 0 0 4 4 4 2 PhoH-like protein AAA_8 PF12780.7 KRZ99354.1 - 0.0024 17.2 1.9 13 5.0 0.0 5.7 6 0 0 6 6 5 0 P-loop containing dynein motor region D4 dNK PF01712.19 KRZ99354.1 - 0.0093 15.8 5.3 12 5.7 0.0 6.0 6 0 0 6 6 5 0 Deoxynucleoside kinase CPT PF07931.12 KRZ99354.1 - 0.024 14.5 1.1 40 4.0 0.0 5.1 5 1 0 5 5 3 0 Chloramphenicol phosphotransferase-like protein ResIII PF04851.15 KRZ99354.1 - 0.024 14.6 19.7 2.2 8.3 0.1 6.6 6 0 0 6 6 5 0 Type III restriction enzyme, res subunit PRK PF00485.18 KRZ99354.1 - 0.033 13.9 1.8 6 6.5 0.0 4.3 5 0 0 5 5 3 0 Phosphoribulokinase / Uridine kinase family VWA_2 PF13519.6 KRZ99354.1 - 0.081 13.6 0.1 0.35 11.5 0.1 2.2 1 0 0 1 1 1 0 von Willebrand factor type A domain ATP_bind_1 PF03029.17 KRZ99354.1 - 0.25 11.1 11.4 6.1 6.5 0.4 5.8 6 0 0 6 6 5 0 Conserved hypothetical ATP binding protein MobB PF03205.14 KRZ99354.1 - 1.6 8.7 8.9 31 4.5 0.0 4.8 6 0 0 6 6 5 0 Molybdopterin guanine dinucleotide synthesis protein B SpoIIE PF07228.12 KRZ99355.1 - 2.8e-07 30.6 0.0 5.2e-07 29.8 0.0 1.5 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 KRZ99355.1 - 1.4e-06 28.1 0.0 2.3e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 KRZ99355.1 - 0.002 17.8 0.1 0.13 11.8 0.0 2.1 1 1 1 2 2 2 2 Protein phosphatase 2C DUF3954 PF13128.6 KRZ99355.1 - 0.033 14.0 0.2 0.18 11.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3954) EPSP_synthase PF00275.20 KRZ99356.1 - 1.1e-130 436.2 0.0 1.8e-130 435.4 0.0 1.3 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 KRZ99356.1 - 1.9e-99 332.1 0.1 3.5e-99 331.2 0.1 1.5 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.15 KRZ99356.1 - 2.5e-48 165.3 0.1 9.4e-48 163.4 0.0 2.1 3 0 0 3 3 2 1 Type I 3-dehydroquinase SKI PF01202.22 KRZ99356.1 - 8.4e-33 113.7 0.1 2.8e-32 112.1 0.0 1.9 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.11 KRZ99356.1 - 5.5e-25 87.4 0.0 2.2e-24 85.5 0.0 2.2 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Fe-ADH_2 PF13685.6 KRZ99356.1 - 7.9e-10 38.8 0.0 2e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase SDH_C PF18317.1 KRZ99356.1 - 4.9e-08 32.6 0.1 1.1e-07 31.4 0.1 1.7 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 KRZ99356.1 - 0.00019 21.5 0.0 0.00055 20.0 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.15 KRZ99356.1 - 0.0031 17.7 0.0 0.011 15.9 0.0 1.9 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Fe-ADH PF00465.19 KRZ99356.1 - 0.0056 15.5 0.1 0.013 14.4 0.1 1.6 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Pyr_redox_2 PF07992.14 KRZ99356.1 - 0.036 13.3 0.1 1.1 8.4 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AAA_33 PF13671.6 KRZ99356.1 - 0.18 11.9 0.0 0.45 10.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain PolyA_pol PF01743.20 KRZ99357.1 - 7.1e-30 104.0 0.0 1.4e-29 103.1 0.0 1.5 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 KRZ99357.1 - 1.2e-08 34.6 0.0 2.9e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.6 KRZ99357.1 - 0.00021 21.3 0.0 0.00045 20.2 0.0 1.5 1 0 0 1 1 1 1 tRNA nucleotidyltransferase domain 2 putative DEAD PF00270.29 KRZ99358.1 - 3.6e-43 147.4 0.0 5.6e-43 146.7 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KRZ99358.1 - 4.4e-30 104.3 0.2 2.9e-29 101.7 0.2 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KRZ99358.1 - 0.0019 18.2 0.0 0.004 17.2 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Arcadin_1 PF18653.1 KRZ99358.1 - 0.043 13.9 0.0 0.3 11.2 0.0 2.2 2 0 0 2 2 2 0 Arcadin 1 YdjO PF14169.6 KRZ99359.1 - 1.2 8.9 5.5 0.39 10.5 0.7 2.2 1 1 0 2 2 2 0 Cold-inducible protein YdjO GTP_EFTU PF00009.27 KRZ99360.1 - 1.2e-56 191.4 0.0 2.5e-56 190.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 KRZ99360.1 - 1.6e-14 53.7 0.1 7.5e-14 51.5 0.0 2.1 2 0 0 2 2 2 1 Elongation factor G C-terminus EFG_II PF14492.6 KRZ99360.1 - 4.5e-13 49.1 0.0 1.4e-12 47.5 0.0 1.9 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 KRZ99360.1 - 5e-07 30.0 0.0 1.2e-06 28.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_IV PF03764.18 KRZ99360.1 - 0.00096 18.9 0.0 0.0022 17.8 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV MMR_HSR1 PF01926.23 KRZ99360.1 - 0.039 14.0 0.0 0.15 12.1 0.0 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase CbiA PF01656.23 KRZ99360.1 - 0.15 12.2 0.0 1.6 8.8 0.0 2.6 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Rtt102p PF09510.10 KRZ99362.1 - 0.012 15.9 3.5 0.021 15.0 3.5 1.5 1 1 0 1 1 1 0 Rtt102p-like transcription regulator protein RNase_T PF00929.24 KRZ99363.1 - 6.4e-06 26.8 0.0 2.6e-05 24.8 0.0 2.0 2 0 0 2 2 2 1 Exonuclease DUF3591 PF12157.8 KRZ99365.1 - 8.3e-184 611.3 16.8 8.3e-184 611.3 16.8 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.6 KRZ99365.1 - 3.2e-07 30.1 0.5 9.7e-07 28.5 0.5 1.8 1 0 0 1 1 1 1 Zinc knuckle SeqA PF03925.13 KRZ99365.1 - 0.058 13.4 0.0 0.15 12.0 0.0 1.8 1 0 0 1 1 1 0 SeqA protein C-terminal domain DUF1870 PF08965.10 KRZ99365.1 - 1.5 8.8 5.7 0.76 9.8 0.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1870) Zn_clus PF00172.18 KRZ99366.1 - 1.3e-05 25.2 11.8 2.2e-05 24.5 11.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LicD PF04991.13 KRZ99367.1 - 2e-22 80.5 7.4 8e-18 65.4 0.1 3.3 2 2 1 3 3 3 2 LicD family Glyco_hydro_32N PF00251.20 KRZ99368.1 - 7.5e-88 295.0 11.1 9.7e-88 294.6 11.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 KRZ99368.1 - 1.3e-14 54.5 1.0 2.4e-14 53.6 1.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Aegerolysin PF06355.13 KRZ99368.1 - 0.075 13.1 1.4 1.2 9.2 0.0 3.0 3 0 0 3 3 3 0 Aegerolysin Rad4 PF03835.15 KRZ99369.1 - 6.4e-08 32.4 2.1 8.6e-08 32.0 0.5 1.9 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain Transglut_core PF01841.19 KRZ99369.1 - 8.9e-07 29.4 0.0 1.8e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily NOGCT PF08155.11 KRZ99369.1 - 0.031 14.3 0.2 0.11 12.5 0.2 1.9 1 0 0 1 1 1 0 NOGCT (NUC087) domain HA2 PF04408.23 KRZ99370.1 - 1.4e-18 67.2 0.4 5.8e-18 65.2 0.0 2.3 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KRZ99370.1 - 8.7e-15 55.0 0.6 5.7e-14 52.4 0.0 2.7 4 0 0 4 4 4 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 KRZ99370.1 - 2.5e-11 43.8 0.1 3.4e-10 40.2 0.0 2.4 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 KRZ99370.1 - 8.5e-07 28.9 0.2 2.5e-06 27.4 0.2 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KRZ99370.1 - 2.5e-06 27.8 0.1 6.8e-06 26.4 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KRZ99370.1 - 0.0052 16.5 0.0 0.016 14.9 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KRZ99370.1 - 0.026 14.4 2.7 0.052 13.4 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase AAA_30 PF13604.6 KRZ99370.1 - 0.028 14.1 0.0 0.056 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KRZ99370.1 - 0.061 13.8 0.1 0.061 13.8 0.1 2.6 1 1 1 2 2 2 0 ABC transporter AAA_23 PF13476.6 KRZ99370.1 - 0.077 13.5 0.4 0.077 13.5 0.4 3.3 3 1 1 4 4 4 0 AAA domain tRNA-synt_1b PF00579.25 KRZ99371.1 - 5.4e-75 252.4 0.0 7.9e-75 251.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) TyrRSs_C PF16714.5 KRZ99371.1 - 0.016 15.0 0.1 0.23 11.3 0.1 2.2 1 1 0 1 1 1 0 Tyrosyl-tRNA synthetase C-terminal domain PI3K_C2 PF00792.24 KRZ99372.1 - 0.046 13.6 0.3 4.3 7.2 0.1 2.6 2 1 0 2 2 2 0 Phosphoinositide 3-kinase C2 Inositol_P PF00459.25 KRZ99373.1 - 2.7e-53 181.2 1.6 1.1e-52 179.2 1.6 1.7 1 1 0 1 1 1 1 Inositol monophosphatase family SUR7 PF06687.12 KRZ99374.1 - 6.1e-21 75.0 0.3 9.4e-21 74.4 0.3 1.2 1 0 0 1 1 1 1 SUR7/PalI family EMP70 PF02990.16 KRZ99374.1 - 0.0046 15.7 1.8 0.0047 15.7 0.2 1.7 2 0 0 2 2 2 1 Endomembrane protein 70 UPF0259 PF06790.11 KRZ99374.1 - 0.0048 16.7 2.5 0.0084 15.9 2.5 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0259) DUF3784 PF12650.7 KRZ99374.1 - 0.14 12.3 1.6 7.2 6.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) ABC2_membrane_4 PF12730.7 KRZ99374.1 - 3.7 7.5 11.5 0.6 10.1 0.2 2.1 2 0 0 2 2 2 0 ABC-2 family transporter protein Tht1 PF04163.12 KRZ99376.1 - 1.9e-26 93.0 23.2 1.9e-26 92.9 16.4 2.3 1 1 0 2 2 2 1 Tht1-like nuclear fusion protein Apolipoprotein PF01442.18 KRZ99376.1 - 0.018 14.9 7.4 0.05 13.5 0.6 2.2 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain Colicin PF01024.19 KRZ99376.1 - 0.027 14.3 2.2 0.033 14.1 0.2 2.1 2 0 0 2 2 2 0 Colicin pore forming domain DUF4413 PF14372.6 KRZ99376.1 - 0.031 14.6 1.4 0.22 11.9 1.4 2.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) AAA_32 PF13654.6 KRZ99376.1 - 0.15 10.8 13.1 0.36 9.6 2.5 2.1 2 0 0 2 2 2 0 AAA domain Muted PF14942.6 KRZ99376.1 - 0.18 12.2 20.4 0.18 12.1 5.6 3.7 3 1 0 3 3 3 0 Organelle biogenesis, Muted-like protein DUF948 PF06103.11 KRZ99376.1 - 0.25 11.6 15.2 3.6 7.9 0.5 4.4 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF948) Snapin_Pallidin PF14712.6 KRZ99376.1 - 0.4 11.1 6.5 8 7.0 1.6 3.2 3 0 0 3 3 3 0 Snapin/Pallidin YtxH PF12732.7 KRZ99376.1 - 0.42 11.2 6.6 6.5 7.4 0.9 3.6 2 1 0 2 2 2 0 YtxH-like protein Taxilin PF09728.9 KRZ99376.1 - 0.43 9.7 15.4 0.36 10.0 0.5 2.7 3 0 0 3 3 3 0 Myosin-like coiled-coil protein ApoLp-III PF07464.11 KRZ99376.1 - 0.78 9.8 17.0 3 7.9 2.9 3.3 1 1 3 4 4 4 0 Apolipophorin-III precursor (apoLp-III) IL11 PF07400.11 KRZ99376.1 - 1.4 8.5 5.8 2.8 7.6 0.5 2.8 2 1 0 2 2 2 0 Interleukin 11 NYD-SP28 PF14772.6 KRZ99376.1 - 1.9 8.6 14.4 0.26 11.4 3.9 2.8 2 1 0 2 2 2 0 Sperm tail Exonuc_VII_L PF02601.15 KRZ99376.1 - 2 7.9 9.5 2.5 7.6 0.9 2.1 1 1 1 2 2 2 0 Exonuclease VII, large subunit RasGAP_C PF03836.15 KRZ99376.1 - 3.5 7.8 14.0 0.63 10.2 2.7 3.1 2 1 0 2 2 2 0 RasGAP C-terminus ZYG-11_interact PF05884.12 KRZ99376.1 - 3.8 6.8 10.0 0.61 9.5 3.8 2.1 1 1 0 2 2 2 0 Interactor of ZYG-11 Phasin PF05597.11 KRZ99376.1 - 4 7.5 8.0 19 5.2 0.4 3.0 2 1 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) F_actin_bind PF08919.10 KRZ99376.1 - 4 7.6 7.5 4.4 7.4 1.1 3.5 1 1 2 3 3 3 0 F-actin binding EMC3_TMCO1 PF01956.16 KRZ99376.1 - 4.8 6.9 12.7 0.22 11.2 4.7 2.3 2 1 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like Occludin_ELL PF07303.13 KRZ99376.1 - 6.2 7.6 13.0 0.86 10.4 6.3 2.8 2 1 1 3 3 3 0 Occludin homology domain DUF4451 PF14616.6 KRZ99377.1 - 1.6e-15 57.4 2.1 1.6e-15 57.4 2.1 1.9 2 1 0 2 2 2 1 Domain of unknown function (DUF4451) Lipase_3 PF01764.25 KRZ99378.1 - 3e-31 108.2 0.0 4.3e-31 107.7 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Esterase PF00756.20 KRZ99378.1 - 1.2e-05 25.1 0.0 1.6e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 KRZ99378.1 - 0.00012 21.4 0.0 0.00016 21.0 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KRZ99378.1 - 0.00061 19.5 0.0 0.0009 19.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.13 KRZ99378.1 - 0.012 15.3 0.0 0.019 14.7 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_6 PF12697.7 KRZ99378.1 - 0.018 15.7 0.0 0.023 15.3 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF676 PF05057.14 KRZ99378.1 - 0.019 14.5 0.0 0.032 13.7 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) BBP1_C PF15272.6 KRZ99378.1 - 0.024 14.5 0.0 0.29 11.0 0.1 2.3 2 0 0 2 2 2 0 Spindle pole body component BBP1, C-terminal LIDHydrolase PF10230.9 KRZ99378.1 - 0.059 12.9 0.0 0.089 12.3 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Thioesterase PF00975.20 KRZ99378.1 - 0.09 12.9 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain Lipase3_N PF03893.16 KRZ99378.1 - 0.14 12.2 0.0 0.32 11.0 0.0 1.6 1 0 0 1 1 1 0 Lipase 3 N-terminal region Ribosomal_L1 PF00687.21 KRZ99380.1 - 2.2e-43 148.4 1.0 2.2e-43 148.4 1.0 2.2 2 1 1 3 3 3 1 Ribosomal protein L1p/L10e family Meckelin PF09773.9 KRZ99380.1 - 0.018 13.1 0.0 0.031 12.4 0.0 1.3 1 0 0 1 1 1 0 Meckelin (Transmembrane protein 67) Calcipressin PF04847.12 KRZ99381.1 - 1.6e-14 54.1 0.1 2.7e-14 53.3 0.1 1.3 1 1 0 1 1 1 1 Calcipressin PITH PF06201.13 KRZ99382.1 - 5.2e-32 111.2 0.2 6.4e-32 110.9 0.2 1.1 1 0 0 1 1 1 1 PITH domain His_Phos_1 PF00300.22 KRZ99383.1 - 1.2e-35 122.9 0.0 4.6e-29 101.5 0.1 2.0 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) Nucleoporin_FG PF13634.6 KRZ99384.1 - 1.1e-23 83.9 140.9 7.3e-09 36.4 23.2 6.7 1 1 4 5 5 5 3 Nucleoporin FG repeat region Nup_retrotrp_bd PF10599.9 KRZ99384.1 - 0.88 10.3 0.1 0.88 10.3 0.1 9.3 2 1 4 6 6 6 0 Retro-transposon transporting motif Pex24p PF06398.11 KRZ99385.1 - 1.5e-112 376.2 2.5 1.9e-112 375.9 2.5 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF639 PF04842.12 KRZ99385.1 - 0.076 12.4 0.1 0.15 11.5 0.1 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF639) RWD PF05773.22 KRZ99386.1 - 6.3e-17 61.9 1.7 1.1e-16 61.1 1.7 1.4 1 0 0 1 1 1 1 RWD domain IBR PF01485.21 KRZ99386.1 - 8.6e-15 54.7 42.0 5.4e-10 39.4 5.1 4.3 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-RING_UBOX PF13445.6 KRZ99386.1 - 4.8e-05 23.3 6.0 4.8e-05 23.3 6.0 3.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 KRZ99386.1 - 0.00023 21.4 8.7 0.00023 21.4 8.7 4.2 3 2 2 5 5 5 2 Ring finger domain zf-C3HC4_2 PF13923.6 KRZ99386.1 - 0.0024 17.7 7.2 0.0024 17.7 7.2 4.6 3 2 2 5 5 5 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KRZ99386.1 - 0.0025 17.6 8.5 0.0025 17.6 8.5 4.5 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) DUF3419 PF11899.8 KRZ99386.1 - 0.0051 16.0 0.0 0.0088 15.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) COPIIcoated_ERV PF07970.12 KRZ99387.1 - 1.5e-37 129.6 0.1 2.2e-37 129.0 0.1 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 KRZ99387.1 - 1.9e-23 82.6 0.1 3.5e-23 81.8 0.1 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DUF2627 PF11118.8 KRZ99387.1 - 0.076 13.6 1.7 3.9 8.1 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2627) Fungal_trans_2 PF11951.8 KRZ99388.1 - 3.9e-42 144.4 2.5 6.2e-42 143.8 2.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KRZ99388.1 - 6.8e-08 32.5 10.8 1.5e-07 31.4 10.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SEN1_N PF12726.7 KRZ99389.1 - 1.3e-172 575.9 12.1 1.7e-172 575.5 12.1 1.1 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.6 KRZ99389.1 - 2.3e-75 253.8 1.6 2.3e-75 253.8 1.6 3.5 3 1 0 3 3 3 1 AAA domain AAA_12 PF13087.6 KRZ99389.1 - 4.1e-65 219.2 0.0 1e-64 217.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KRZ99389.1 - 5.3e-08 33.3 0.0 1.2e-06 29.0 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KRZ99389.1 - 3.7e-07 30.1 0.0 0.00087 19.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 KRZ99389.1 - 3.3e-05 23.7 0.2 0.16 11.7 0.0 4.1 4 0 0 4 4 4 2 Viral (Superfamily 1) RNA helicase COX5A PF02284.16 KRZ99390.1 - 0.016 15.2 0.0 0.11 12.5 0.0 2.4 3 0 0 3 3 3 0 Cytochrome c oxidase subunit Va ApbA_C PF08546.11 KRZ99390.1 - 0.024 14.8 0.1 0.24 11.6 0.0 2.3 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA C terminal B PF02216.16 KRZ99390.1 - 0.49 10.4 0.1 0.49 10.4 0.1 3.0 3 0 0 3 3 3 0 B domain EF-hand_1 PF00036.32 KRZ99391.1 - 4.7e-27 91.5 16.5 2.4e-06 26.7 0.5 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KRZ99391.1 - 1.2e-21 76.9 7.9 3.2e-11 43.5 2.0 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KRZ99391.1 - 2.6e-21 73.7 12.0 1.2e-05 24.9 0.0 4.5 3 1 1 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KRZ99391.1 - 4.2e-17 60.8 15.4 2.1e-05 23.8 0.3 4.8 4 1 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 KRZ99391.1 - 3.4e-11 42.8 20.1 0.0084 15.9 1.7 4.6 2 1 2 4 4 4 4 EF-hand domain pair EF-hand_4 PF12763.7 KRZ99391.1 - 7.8e-06 25.8 6.8 0.5 10.4 0.1 3.8 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KRZ99391.1 - 1.2e-05 25.5 0.0 0.18 12.2 0.0 2.3 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 KRZ99391.1 - 0.011 16.1 0.1 22 5.5 0.0 3.1 2 1 1 3 3 3 0 EF-hand domain Sigma54_CBD PF04963.13 KRZ99391.1 - 0.029 14.2 0.0 0.71 9.7 0.0 2.4 1 1 0 2 2 2 0 Sigma-54 factor, core binding domain Lip_prot_lig_C PF10437.9 KRZ99391.1 - 0.053 13.5 0.3 1.5 8.9 0.1 2.3 2 0 0 2 2 2 0 Bacterial lipoate protein ligase C-terminus Glycos_trans_3N PF02885.17 KRZ99391.1 - 0.054 13.4 0.1 5.3 7.0 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase family, helical bundle domain adh_short_C2 PF13561.6 KRZ99392.1 - 4e-44 150.9 0.0 4.9e-44 150.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KRZ99392.1 - 8.8e-43 146.0 0.2 1.1e-42 145.7 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KRZ99392.1 - 3.7e-16 59.6 0.1 6.1e-16 58.9 0.1 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KRZ99392.1 - 0.00018 20.8 0.1 0.00024 20.3 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KRZ99392.1 - 0.00028 20.4 0.0 0.00041 19.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KRZ99392.1 - 0.00047 19.7 0.0 0.00064 19.2 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase DUF1776 PF08643.10 KRZ99392.1 - 0.023 14.1 0.8 0.047 13.1 0.8 1.5 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) NAD_binding_7 PF13241.6 KRZ99392.1 - 0.06 13.8 0.1 0.59 10.6 0.3 2.0 2 0 0 2 2 2 0 Putative NAD(P)-binding DUF4972 PF16342.5 KRZ99392.1 - 0.073 12.8 0.0 0.65 9.7 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4972) 3HCDH_N PF02737.18 KRZ99392.1 - 0.12 12.3 0.4 0.28 11.0 0.2 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SPOC PF07744.13 KRZ99392.1 - 0.13 12.1 0.0 0.34 10.8 0.0 1.6 2 0 0 2 2 2 0 SPOC domain Glyco_hydro_79n PF03662.14 KRZ99392.1 - 0.18 10.7 0.0 0.25 10.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 79, N-terminal domain CNH PF00780.22 KRZ99393.1 - 5.8e-39 134.4 0.5 1.1e-38 133.4 0.5 1.5 1 0 0 1 1 1 1 CNH domain PH_5 PF15405.6 KRZ99393.1 - 1.4e-06 28.4 0.9 5.9e-06 26.4 0.0 2.6 3 0 0 3 3 3 1 Pleckstrin homology domain PH PF00169.29 KRZ99393.1 - 1.8e-05 25.1 0.0 0.00013 22.4 0.0 2.7 1 0 0 1 1 1 1 PH domain RhoGEF PF00621.20 KRZ99393.1 - 0.0011 19.2 0.6 0.0032 17.8 0.6 1.9 1 0 0 1 1 1 1 RhoGEF domain SHNi-TPR PF10516.9 KRZ99394.1 - 8.8e-15 53.9 0.8 8.8e-15 53.9 0.8 2.3 2 0 0 2 2 2 1 SHNi-TPR TPR_2 PF07719.17 KRZ99394.1 - 0.16 12.2 3.7 4.7 7.6 1.6 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 KRZ99394.1 - 0.2 12.0 3.2 8.7 6.7 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Rsa3 PF14615.6 KRZ99395.1 - 6.9e-20 70.4 1.0 6.9e-20 70.4 1.0 1.8 2 0 0 2 2 2 1 Ribosome-assembly protein 3 IMUP PF15761.5 KRZ99395.1 - 0.034 14.8 4.0 0.034 14.8 4.0 2.2 2 1 0 2 2 2 0 Immortalisation up-regulated protein GTP_EFTU PF00009.27 KRZ99396.1 - 4e-41 140.7 1.4 4.6e-41 140.5 1.4 1.0 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KRZ99396.1 - 2.5e-05 24.3 0.0 3.1e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Sde2_N_Ubi PF13019.6 KRZ99397.1 - 4.4e-10 39.6 0.6 4.4e-10 39.6 0.6 1.7 2 1 1 3 3 3 1 Silencing defective 2 N-terminal ubiquitin domain Snf7 PF03357.21 KRZ99397.1 - 0.0073 15.9 5.8 0.012 15.2 5.8 1.3 1 0 0 1 1 1 1 Snf7 HALZ PF02183.18 KRZ99397.1 - 0.0075 16.5 5.0 0.016 15.4 5.0 1.5 1 0 0 1 1 1 1 Homeobox associated leucine zipper Acetyltransf_11 PF13720.6 KRZ99397.1 - 0.048 14.1 0.2 0.095 13.2 0.2 1.5 1 0 0 1 1 1 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 TLE_N PF03920.15 KRZ99397.1 - 0.048 13.7 1.1 0.074 13.1 1.1 1.3 1 0 0 1 1 1 0 Groucho/TLE N-terminal Q-rich domain DUF4298 PF14131.6 KRZ99397.1 - 1.2 9.2 7.1 0.58 10.1 3.5 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4298) PQ-loop PF04193.14 KRZ99398.1 - 1.3e-21 76.1 14.0 4.4e-12 45.6 1.3 2.6 2 0 0 2 2 2 2 PQ loop repeat ER_lumen_recept PF00810.18 KRZ99398.1 - 0.99 10.2 12.8 0.041 14.7 4.4 2.4 2 1 1 3 3 3 0 ER lumen protein retaining receptor DUF4191 PF13829.6 KRZ99398.1 - 1.6 8.0 5.9 5.8 6.2 0.7 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4191) Bul1_N PF04425.12 KRZ99399.1 - 2.4e-87 293.6 0.5 5.5e-87 292.4 0.5 1.5 1 0 0 1 1 1 1 Bul1 N terminus Bul1_C PF04426.12 KRZ99399.1 - 7.3e-23 81.3 5.5 3.6e-22 79.1 5.5 2.2 1 1 0 1 1 1 1 Bul1 C terminus INCENP_ARK-bind PF03941.15 KRZ99400.1 - 1.7e-16 59.9 0.3 7.7e-16 57.8 0.2 2.3 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region TPR_1 PF00515.28 KRZ99401.1 - 2.6e-10 39.7 10.0 0.00024 20.8 1.9 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KRZ99401.1 - 1.3e-08 34.3 4.2 0.085 13.0 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 KRZ99401.1 - 0.00033 20.9 0.4 0.48 10.7 0.0 2.9 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 KRZ99401.1 - 0.002 18.6 0.0 5.8 7.5 0.0 3.3 3 1 1 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KRZ99401.1 - 0.041 14.1 3.7 0.11 12.8 3.5 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 KRZ99401.1 - 0.2 11.7 3.1 15 5.7 0.0 3.5 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_8 PF13181.6 KRZ99401.1 - 7.3 7.1 11.5 20 5.7 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Bul1_N PF04425.12 KRZ99402.1 - 3e-109 365.8 7.6 1.5e-108 363.5 7.6 1.9 1 1 0 1 1 1 1 Bul1 N terminus Bul1_C PF04426.12 KRZ99402.1 - 1.9e-16 60.3 4.3 1.9e-16 60.3 4.3 2.9 3 1 0 3 3 3 1 Bul1 C terminus Bul1_N PF04425.12 KRZ99403.1 - 5.8e-112 374.7 8.8 1.6e-111 373.3 8.8 1.7 1 0 0 1 1 1 1 Bul1 N terminus Bul1_C PF04426.12 KRZ99403.1 - 5.4e-25 88.3 9.2 3.5e-24 85.7 9.2 2.2 1 1 0 1 1 1 1 Bul1 C terminus G_glu_transpept PF01019.21 KRZ99404.1 - 8e-135 450.5 0.0 9.4e-135 450.3 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Carn_acyltransf PF00755.20 KRZ99405.1 - 1e-210 701.3 0.2 1.8e-210 700.5 0.2 1.4 1 1 0 1 1 1 1 Choline/Carnitine o-acyltransferase DUF1708 PF08101.11 KRZ99406.1 - 5.4e-130 434.4 6.0 4.8e-128 428.0 6.0 2.5 1 1 0 1 1 1 1 Domain of unknown function (DUF1708) bZIP_1 PF00170.21 KRZ99407.1 - 4.8e-07 29.8 2.5 4.8e-07 29.8 2.5 2.1 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 KRZ99407.1 - 2.7e-05 24.2 3.0 2.7e-05 24.2 3.0 2.6 2 1 0 2 2 2 1 Basic region leucine zipper Caldesmon PF02029.15 KRZ99407.1 - 0.0044 15.8 23.3 0.0062 15.4 23.3 1.3 1 0 0 1 1 1 1 Caldesmon bZIP_Maf PF03131.17 KRZ99407.1 - 0.035 14.6 1.6 0.035 14.6 1.6 3.5 2 1 1 3 3 3 0 bZIP Maf transcription factor Mitofilin PF09731.9 KRZ99407.1 - 0.081 11.8 25.0 0.12 11.2 25.0 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Pex24p PF06398.11 KRZ99408.1 - 1.6e-82 277.5 13.8 1.9e-82 277.2 13.8 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin YwiC PF14256.6 KRZ99408.1 - 3.3 8.0 8.1 0.61 10.4 0.2 2.2 2 0 0 2 2 2 0 YwiC-like protein Rpr2 PF04032.16 KRZ99409.1 - 5.5e-13 49.0 0.2 5.5e-13 49.0 0.2 2.0 2 1 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Zn_clus PF00172.18 KRZ99410.1 - 1.4e-06 28.3 10.3 2.5e-06 27.5 10.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SapB_1 PF05184.15 KRZ99410.1 - 0.042 13.9 0.2 0.16 12.0 0.0 2.2 2 0 0 2 2 2 0 Saposin-like type B, region 1 EMC1_C PF07774.13 KRZ99411.1 - 9.1e-62 208.5 3.8 2.2e-61 207.3 3.8 1.7 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 KRZ99411.1 - 1.1e-05 25.2 0.0 0.0083 15.7 0.0 2.7 2 0 0 2 2 2 2 PQQ-like domain PQQ PF01011.21 KRZ99411.1 - 0.0014 18.5 0.8 0.065 13.2 0.0 3.4 3 0 0 3 3 3 1 PQQ enzyme repeat RHS PF03527.14 KRZ99411.1 - 0.077 12.8 0.1 11 5.8 0.0 2.4 2 0 0 2 2 2 0 RHS protein RPAP1_C PF08620.10 KRZ99412.1 - 6e-28 96.7 0.1 1.1e-27 95.9 0.1 1.5 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 KRZ99412.1 - 2e-17 62.7 8.6 2e-17 62.7 8.6 2.3 2 0 0 2 2 2 1 RPAP1-like, N-terminal DHHC PF01529.20 KRZ99413.1 - 2.3e-27 95.7 10.4 2.3e-27 95.7 10.4 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase AsmA PF05170.14 KRZ99413.1 - 0.98 8.1 4.0 12 4.5 0.1 2.2 2 0 0 2 2 2 0 AsmA family Sid-5 PF17204.3 KRZ99413.1 - 1.4 9.1 7.5 2.4 8.4 2.0 3.0 2 1 1 3 3 3 0 Sid-5 family Chordopox_G3 PF06129.12 KRZ99413.1 - 8.4 7.2 8.2 3.5 8.4 0.3 3.2 3 0 0 3 3 3 0 Chordopoxvirus G3 protein MAT1 PF06391.13 KRZ99414.1 - 5.8e-61 205.9 29.0 7.4e-61 205.5 29.0 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 KRZ99414.1 - 4.6e-27 93.6 10.1 9e-27 92.7 10.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KRZ99414.1 - 0.00064 19.5 5.3 0.0012 18.6 5.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KRZ99414.1 - 0.0014 18.9 7.2 0.0025 18.1 7.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KRZ99414.1 - 0.0031 17.4 5.5 0.0086 15.9 5.5 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KRZ99414.1 - 0.014 15.2 7.5 0.03 14.2 7.5 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) HMG_box_5 PF14887.6 KRZ99414.1 - 0.082 12.9 1.6 0.2 11.7 1.6 1.7 1 0 0 1 1 1 0 HMG (high mobility group) box 5 zf-piccolo PF05715.13 KRZ99414.1 - 0.13 12.5 1.4 0.25 11.5 1.4 1.5 1 0 0 1 1 1 0 Piccolo Zn-finger zf-RING_UBOX PF13445.6 KRZ99414.1 - 0.42 10.7 9.2 0.94 9.6 9.2 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 KRZ99414.1 - 0.51 10.3 9.4 13 5.9 9.8 2.4 1 1 1 2 2 2 0 zinc-RING finger domain DUF3605 PF12239.8 KRZ99414.1 - 1.6 9.0 8.5 5.8 7.2 2.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3605) zf-RING_4 PF14570.6 KRZ99414.1 - 3.4 7.5 9.5 69 3.4 10.0 2.4 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 KRZ99414.1 - 6.4 6.7 9.7 32 4.5 0.3 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 EcsC PF12787.7 KRZ99415.1 - 0.045 13.4 0.2 0.11 12.1 0.2 1.7 1 0 0 1 1 1 0 EcsC protein family CGI-121 PF08617.10 KRZ99416.1 - 8.2e-37 126.8 0.7 9.3e-37 126.6 0.7 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Phage_TAC_8 PF10666.9 KRZ99416.1 - 0.048 13.9 0.1 0.3 11.3 0.0 2.0 2 0 0 2 2 2 0 Phage tail assembly chaperone protein Gp14 ()A118 XPG_N PF00752.17 KRZ99417.1 - 3.1e-23 82.1 0.0 6.2e-23 81.2 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 KRZ99417.1 - 4.7e-22 78.2 0.6 1.4e-21 76.6 0.0 2.2 2 0 0 2 2 2 1 XPG I-region 5_3_exonuc PF01367.20 KRZ99417.1 - 8.7e-06 26.3 0.0 3.6e-05 24.3 0.0 2.1 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold XPG_I_2 PF12813.7 KRZ99417.1 - 0.0019 17.7 0.0 0.006 16.1 0.0 1.9 1 0 0 1 1 1 1 XPG domain containing HHH_5 PF14520.6 KRZ99417.1 - 0.0026 18.3 0.1 1.6 9.4 0.0 2.8 2 0 0 2 2 2 2 Helix-hairpin-helix domain HHH_2 PF12826.7 KRZ99417.1 - 0.0067 16.5 0.0 0.033 14.3 0.0 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix motif Pox_G5 PF04599.12 KRZ99417.1 - 0.053 12.5 0.1 0.097 11.7 0.1 1.3 1 0 0 1 1 1 0 Poxvirus G5 protein TEA PF01285.18 KRZ99418.1 - 6.3e-07 29.4 0.1 2.1e-06 27.7 0.1 2.0 1 0 0 1 1 1 1 TEA/ATTS domain Polysacc_deac_1 PF01522.21 KRZ99418.1 - 0.026 14.4 0.1 0.081 12.8 0.1 1.8 1 0 0 1 1 1 0 Polysaccharide deacetylase Pkinase PF00069.25 KRZ99419.1 - 2.8e-67 226.9 0.0 3.8e-67 226.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KRZ99419.1 - 8.7e-48 162.8 0.0 1.2e-47 162.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KRZ99419.1 - 0.00035 19.5 0.0 0.00053 18.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KRZ99419.1 - 0.0055 16.1 0.0 0.15 11.4 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KRZ99419.1 - 0.015 14.6 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KRZ99419.1 - 0.028 13.4 0.3 1.4 7.8 0.3 2.4 1 1 0 1 1 1 0 Haspin like kinase domain RRT14 PF17075.5 KRZ99419.1 - 0.082 13.0 0.3 0.34 11.0 0.1 1.9 2 0 0 2 2 2 0 Regular of rDNA transcription protein 14 ArfGap PF01412.18 KRZ99420.1 - 3.4e-29 101.3 2.5 1e-28 99.8 0.3 2.9 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf PH PF00169.29 KRZ99420.1 - 1.5e-14 54.3 0.2 4.3e-14 52.9 0.2 1.9 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 KRZ99420.1 - 3.6e-07 30.6 0.5 2.7e-06 27.8 0.5 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain PH_6 PF15406.6 KRZ99420.1 - 0.00091 19.5 0.0 0.0022 18.3 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain RlaP PF10127.9 KRZ99421.1 - 2.8e-05 23.8 0.1 4.9e-05 23.1 0.1 1.5 1 1 0 1 1 1 1 RNA repair pathway DNA polymerase beta family NTP_transf_2 PF01909.23 KRZ99421.1 - 8.1e-05 22.8 0.0 0.00017 21.8 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 KRZ99421.1 - 9e-05 22.5 0.0 0.00035 20.6 0.0 2.0 2 0 0 2 2 2 1 Polymerase beta, Nucleotidyltransferase RNA_pol_Rpb1_1 PF04997.12 KRZ99421.1 - 0.0072 15.7 0.5 0.01 15.2 0.5 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 ADH_N PF08240.12 KRZ99422.1 - 4.4e-26 90.9 0.3 6e-26 90.5 0.3 1.2 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 KRZ99422.1 - 0.17 11.8 0.1 0.31 10.9 0.1 1.4 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase Nairo_nucleo PF02477.15 KRZ99423.1 - 0.11 11.2 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Nucleocapsid N protein Polyketide_cyc2 PF10604.9 KRZ99424.1 - 0.00022 21.5 0.0 0.00026 21.3 0.0 1.2 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Na_H_Exchanger PF00999.21 KRZ99425.1 - 3.4e-58 197.3 43.7 4.7e-58 196.8 43.7 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Metallophos PF00149.28 KRZ99426.1 - 0.039 14.5 0.0 0.046 14.2 0.0 1.1 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase Cytochrom_B562 PF07361.11 KRZ99426.1 - 0.053 14.2 0.4 0.14 12.8 0.3 1.8 1 1 0 1 1 1 0 Cytochrome b562 AAA_23 PF13476.6 KRZ99426.1 - 0.2 12.1 3.4 0.35 11.3 3.4 1.4 1 1 0 1 1 1 0 AAA domain Fungal_trans PF04082.18 KRZ99427.1 - 1e-05 24.7 8.9 2.4e-05 23.5 8.4 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain RTA1 PF04479.13 KRZ99428.1 - 6.9e-68 228.3 13.8 6.9e-68 228.3 13.8 1.7 2 0 0 2 2 2 1 RTA1 like protein MTABC_N PF16185.5 KRZ99428.1 - 3.3 7.1 9.8 0.24 10.9 3.5 1.9 2 0 0 2 2 2 0 Mitochondrial ABC-transporter N-terminal five TM region Fungal_trans PF04082.18 KRZ99429.1 - 1.6e-11 43.8 0.8 1.6e-11 43.8 0.8 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KRZ99429.1 - 2.5e-08 33.9 10.7 4.9e-08 33.0 10.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DASH_Dad4 PF08650.10 KRZ99429.1 - 0.48 10.4 4.8 21 5.2 0.1 3.3 2 0 0 2 2 2 0 DASH complex subunit Dad4 Sugar_tr PF00083.24 KRZ99430.1 - 2.4e-38 132.2 17.2 4.2e-33 114.9 5.2 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KRZ99430.1 - 1.1e-29 103.5 23.0 7.6e-29 100.7 23.0 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Peptidase_M1_N PF17900.1 KRZ99431.1 - 4.9e-23 82.3 0.2 5.8e-23 82.0 0.2 1.1 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Sel1 PF08238.12 KRZ99432.1 - 8.1e-08 32.7 1.6 0.0024 18.5 0.1 3.5 3 0 0 3 3 3 3 Sel1 repeat SAC3_GANP PF03399.16 KRZ99434.1 - 4.2e-14 52.6 10.7 9.5e-13 48.2 10.7 2.2 1 1 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 KRZ99434.1 - 0.043 13.8 2.0 0.23 11.4 0.4 2.4 1 1 1 2 2 2 0 CSN8/PSMD8/EIF3K family Peptidase_C12 PF01088.21 KRZ99435.1 - 2e-51 174.7 0.0 2.3e-51 174.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Pkinase PF00069.25 KRZ99437.1 - 2.1e-71 240.4 0.1 2.6e-71 240.1 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KRZ99437.1 - 1.5e-39 135.8 0.0 2.1e-39 135.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KRZ99437.1 - 5.8e-07 29.1 0.0 7.8e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KRZ99437.1 - 1.8e-06 27.0 0.0 2.9e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_C PF00433.24 KRZ99437.1 - 0.0014 19.3 0.7 0.0033 18.1 0.2 1.9 2 0 0 2 2 2 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 KRZ99437.1 - 0.0044 16.0 0.4 0.0072 15.3 0.4 1.3 1 0 0 1 1 1 1 Haspin like kinase domain HnRNPA1 PF11627.8 KRZ99437.1 - 0.13 12.5 0.3 0.28 11.4 0.3 1.5 1 0 0 1 1 1 0 Nuclear factor hnRNPA1 RRP36 PF06102.12 KRZ99438.1 - 0.8 9.7 8.4 0.14 12.2 3.2 2.0 2 0 0 2 2 2 0 rRNA biogenesis protein RRP36 PX PF00787.24 KRZ99439.1 - 1.2e-09 38.1 0.2 2.9e-09 36.9 0.2 1.6 1 0 0 1 1 1 1 PX domain SH3_1 PF00018.28 KRZ99439.1 - 1.5e-08 34.1 0.0 3.6e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KRZ99439.1 - 0.00013 21.5 0.1 0.00026 20.6 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KRZ99439.1 - 0.0069 16.2 0.0 0.015 15.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Zn_clus PF00172.18 KRZ99440.1 - 6.1e-09 35.9 5.1 1e-08 35.2 5.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FKS1_dom1 PF14288.6 KRZ99440.1 - 0.56 10.5 6.2 1.2 9.5 6.2 1.5 1 0 0 1 1 1 0 1,3-beta-glucan synthase subunit FKS1, domain-1 RSN1_7TM PF02714.15 KRZ99441.1 - 2.9e-87 292.5 34.3 2.9e-87 292.5 34.3 2.4 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KRZ99441.1 - 3.7e-36 124.2 7.7 3.7e-36 124.2 7.7 3.1 2 1 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KRZ99441.1 - 2.2e-21 76.9 0.1 4.2e-21 75.9 0.1 1.5 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter zf-RanBP PF00641.18 KRZ99442.1 - 2.2e-15 55.7 18.0 1.3e-10 40.4 2.2 2.5 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RNase_T PF00929.24 KRZ99442.1 - 6.3e-08 33.3 0.1 1.7e-07 31.9 0.1 1.7 1 0 0 1 1 1 1 Exonuclease RRM_1 PF00076.22 KRZ99442.1 - 9.5e-06 25.3 0.0 0.024 14.4 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ETRAMP PF09716.10 KRZ99442.1 - 0.026 14.6 0.5 0.94 9.6 0.2 2.8 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) RRM_1 PF00076.22 KRZ99444.1 - 4.6e-19 68.0 0.1 8.5e-19 67.1 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KRZ99444.1 - 0.089 12.9 0.0 0.18 12.0 0.0 1.6 1 1 0 1 1 1 0 RNA recognition motif OB_RNB PF08206.11 KRZ99444.1 - 0.1 12.3 0.4 0.22 11.2 0.4 1.5 1 0 0 1 1 1 0 Ribonuclease B OB domain RNA_pol_Rbc25 PF08292.12 KRZ99445.1 - 3.6e-45 153.3 2.1 8e-45 152.2 2.1 1.6 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 KRZ99445.1 - 2.9e-16 59.6 0.0 4.2e-16 59.1 0.0 1.2 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 KRZ99445.1 - 0.013 15.8 0.0 0.025 14.9 0.0 1.5 1 1 0 1 1 1 0 S1 RNA binding domain AAA PF00004.29 KRZ99446.1 - 2.8e-40 137.8 0.0 5.2e-40 136.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KRZ99446.1 - 4.4e-07 29.6 0.0 1.1e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KRZ99446.1 - 4.8e-05 23.4 0.1 0.00024 21.1 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KRZ99446.1 - 0.00012 22.3 0.0 0.00024 21.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KRZ99446.1 - 0.00013 22.2 0.0 0.0027 18.0 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 KRZ99446.1 - 0.00039 20.8 0.1 0.0043 17.5 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 KRZ99446.1 - 0.00082 18.6 0.0 0.0015 17.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 KRZ99446.1 - 0.0032 17.2 0.0 0.0062 16.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 KRZ99446.1 - 0.013 15.7 0.0 0.022 15.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KRZ99446.1 - 0.016 14.7 0.0 0.045 13.3 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_3 PF07726.11 KRZ99446.1 - 0.017 15.0 0.0 0.085 12.7 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KRZ99446.1 - 0.024 14.8 0.0 0.053 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KRZ99446.1 - 0.025 15.0 0.0 0.074 13.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 KRZ99446.1 - 0.025 15.1 0.0 0.06 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KRZ99446.1 - 0.03 13.7 0.0 0.1 11.9 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 KRZ99446.1 - 0.036 13.8 0.0 0.073 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 KRZ99446.1 - 0.047 12.9 0.0 0.078 12.2 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain Sigma54_activat PF00158.26 KRZ99446.1 - 0.1 12.3 0.0 0.36 10.5 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 KRZ99446.1 - 0.11 12.2 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.6 KRZ99446.1 - 0.14 12.2 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 KRZ99446.1 - 0.19 11.8 0.0 0.47 10.6 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain FAD_binding_2 PF00890.24 KRZ99447.1 - 2.4e-124 415.6 2.3 3e-124 415.3 2.3 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 KRZ99447.1 - 4.2e-44 149.6 0.2 6.5e-44 149.0 0.2 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 KRZ99447.1 - 5.8e-06 25.7 0.3 0.00016 21.0 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KRZ99447.1 - 7e-06 25.4 0.4 0.0013 17.9 0.7 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.17 KRZ99447.1 - 7.2e-06 25.4 0.2 0.0029 16.9 0.1 2.4 2 0 0 2 2 2 2 Thi4 family FAD_binding_3 PF01494.19 KRZ99447.1 - 0.0034 16.7 0.1 0.0065 15.8 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KRZ99447.1 - 0.0052 16.4 1.0 0.019 14.6 1.0 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KRZ99447.1 - 0.043 12.5 0.0 0.13 11.0 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein Zn_clus PF00172.18 KRZ99448.1 - 1.1e-05 25.4 11.0 1.9e-05 24.7 11.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mhr1 PF12829.7 KRZ99449.1 - 3.7e-22 78.2 0.7 3.7e-22 78.2 0.7 1.8 2 0 0 2 2 2 1 Transcriptional regulation of mitochondrial recombination ABA_GPCR PF12430.8 KRZ99450.1 - 6.5e-53 179.2 13.4 6.5e-53 179.2 13.4 1.9 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 KRZ99450.1 - 3.9e-22 78.1 1.2 1.7e-21 76.1 0.2 2.7 2 0 0 2 2 2 1 The Golgi pH Regulator (GPHR) Family N-terminal SUR7 PF06687.12 KRZ99450.1 - 0.0013 18.4 1.3 0.0013 18.4 1.3 3.0 2 1 0 2 2 2 1 SUR7/PalI family DUF2666 PF10869.8 KRZ99450.1 - 0.0031 17.7 0.6 0.014 15.6 0.1 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF2666) FMO-like PF00743.19 KRZ99451.1 - 4.5e-20 71.6 0.2 9.6e-18 63.9 0.1 2.7 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KRZ99451.1 - 8.6e-08 32.3 0.1 3.7e-07 30.3 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KRZ99451.1 - 1e-07 31.4 0.0 1.7e-05 24.2 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KRZ99451.1 - 1.6e-06 27.6 0.0 0.0045 16.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KRZ99451.1 - 6.1e-06 26.3 0.0 0.0034 17.4 0.0 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KRZ99451.1 - 0.00021 20.6 0.0 0.026 13.8 0.0 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KRZ99451.1 - 0.0016 18.1 0.0 0.063 12.9 0.0 3.1 2 1 2 4 4 4 1 FAD dependent oxidoreductase Thi4 PF01946.17 KRZ99451.1 - 0.13 11.5 0.0 1.4 8.1 0.0 2.3 3 0 0 3 3 3 0 Thi4 family CDO_I PF05995.12 KRZ99452.1 - 1.7e-39 134.9 0.0 2.9e-39 134.1 0.0 1.3 1 0 0 1 1 1 1 Cysteine dioxygenase type I YlbD_coat PF14071.6 KRZ99452.1 - 0.0086 16.3 1.9 0.013 15.7 1.9 1.2 1 0 0 1 1 1 1 Putative coat protein PCO_ADO PF07847.12 KRZ99452.1 - 0.55 9.6 6.5 0.14 11.6 1.6 2.2 2 1 0 2 2 2 0 PCO_ADO SLAC1 PF03595.17 KRZ99453.1 - 8e-81 271.8 40.3 9.2e-81 271.6 40.3 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel SLAC1 PF03595.17 KRZ99454.1 - 4.4e-74 249.7 40.5 5.1e-74 249.4 40.5 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel UL45 PF05473.12 KRZ99454.1 - 9.6 5.8 5.8 4.5 6.8 1.4 2.4 2 0 0 2 2 2 0 UL45 protein, carbohydrate-binding C-type lectin-like SLAC1 PF03595.17 KRZ99455.1 - 4.3e-73 246.4 37.4 4.9e-73 246.2 37.4 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel OppC_N PF12911.7 KRZ99455.1 - 0.69 9.9 5.9 14 5.7 0.0 3.5 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C Lig_chan PF00060.26 KRZ99455.1 - 8.9 6.1 6.9 30 4.4 6.6 2.2 1 1 0 1 1 1 0 Ligand-gated ion channel Trs65 PF12735.7 KRZ99456.1 - 1.5e-69 234.8 7.4 2.3e-69 234.2 7.4 1.3 1 0 0 1 1 1 1 TRAPP trafficking subunit Trs65 DUF4451 PF14616.6 KRZ99457.1 - 2.5e-30 105.2 7.6 5.5e-30 104.1 6.4 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4451) AA_permease_2 PF13520.6 KRZ99458.1 - 1.5e-51 175.6 51.3 1.9e-51 175.2 51.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KRZ99458.1 - 1.7e-22 79.7 42.3 2.3e-22 79.3 42.3 1.1 1 0 0 1 1 1 1 Amino acid permease HARE-HTH PF05066.13 KRZ99458.1 - 0.012 16.0 0.0 0.022 15.1 0.0 1.4 1 0 0 1 1 1 0 HB1, ASXL, restriction endonuclease HTH domain Gpr1_Fun34_YaaH PF01184.19 KRZ99459.1 - 5.8e-82 274.3 23.4 6.7e-82 274.1 23.4 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family MASE3 PF17159.4 KRZ99459.1 - 0.27 10.8 14.8 1.9 8.1 14.8 2.0 1 1 0 1 1 1 0 Membrane-associated sensor domain Big_3_5 PF16640.5 KRZ99459.1 - 0.6 10.3 2.6 1.6 9.0 0.1 2.1 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) MFS_1 PF07690.16 KRZ99460.1 - 8.4e-28 97.3 27.0 8.4e-28 97.3 27.0 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily SLATT_5 PF18160.1 KRZ99460.1 - 0.37 10.1 2.5 4.3 6.6 0.4 2.8 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 PHO4 PF01384.20 KRZ99460.1 - 5.6 5.9 14.7 3.2 6.7 0.5 2.8 2 1 0 2 2 2 0 Phosphate transporter family Transp_cyt_pur PF02133.15 KRZ99461.1 - 2e-63 214.7 40.9 2.5e-63 214.4 40.9 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin FMO-like PF00743.19 KRZ99462.1 - 3.9e-25 88.3 4.7 4.9e-12 45.1 0.3 3.2 2 2 1 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KRZ99462.1 - 3.2e-12 46.3 0.2 5.5e-10 39.0 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KRZ99462.1 - 1.5e-10 40.8 0.0 4.6e-08 32.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KRZ99462.1 - 4e-07 29.5 0.6 4.5e-05 22.7 0.1 2.7 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KRZ99462.1 - 0.0041 17.1 0.0 0.72 9.8 0.0 3.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 KRZ99462.1 - 0.009 15.6 0.0 1.2 8.7 0.0 2.6 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KRZ99462.1 - 0.17 12.4 0.0 1.2 9.7 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 2OG-FeII_Oxy PF03171.20 KRZ99463.1 - 4.9e-14 52.6 0.0 1.1e-13 51.5 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KRZ99463.1 - 1.4e-12 48.4 0.0 2.5e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal SSF PF00474.17 KRZ99464.1 - 2.2e-26 92.7 17.6 2.2e-26 92.7 17.6 1.6 2 0 0 2 2 2 1 Sodium:solute symporter family SSF PF00474.17 KRZ99465.1 - 7.3e-20 71.2 27.2 1e-19 70.7 27.2 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family DUF1656 PF07869.12 KRZ99465.1 - 5 7.2 13.4 0.77 9.8 6.8 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1656) Fungal_trans PF04082.18 KRZ99466.1 - 1.4e-15 57.1 0.8 2.7e-15 56.1 0.8 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.24 KRZ99467.1 - 3e-13 49.5 5.1 6.5e-13 48.3 5.1 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KRZ99467.1 - 3.8e-10 39.2 2.7 3.8e-10 39.2 2.7 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.16 KRZ99468.1 - 1.6e-13 50.3 6.2 2.1e-13 50.0 6.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KRZ99468.1 - 1.8e-11 43.6 4.9 2.3e-11 43.3 4.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter RRM_1 PF00076.22 KRZ99469.1 - 1.6e-09 37.4 0.6 6.7e-06 25.8 0.0 3.2 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KRZ99469.1 - 0.001 19.1 0.0 0.0023 18.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif DUF3069 PF11269.8 KRZ99469.1 - 0.059 13.6 2.2 0.2 11.9 2.2 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3069) EMC3_TMCO1 PF01956.16 KRZ99469.1 - 1.6 8.5 11.9 1.2 8.8 1.8 2.3 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like DUF1674 PF07896.12 KRZ99470.1 - 6.1e-16 58.6 3.3 1.2e-15 57.7 3.3 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) Methyltransf_16 PF10294.9 KRZ99471.1 - 2.5e-17 63.1 0.1 2.4e-16 60.0 0.0 2.2 2 0 0 2 2 2 1 Lysine methyltransferase Methyltransf_23 PF13489.6 KRZ99471.1 - 9.6e-06 25.5 0.0 3.1e-05 23.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Aminotran_1_2 PF00155.21 KRZ99472.1 - 7.3e-71 239.2 0.0 8.4e-71 239.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KRZ99472.1 - 0.023 13.2 0.0 0.036 12.6 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KRZ99472.1 - 0.052 12.5 0.0 0.13 11.1 0.0 1.6 1 1 0 1 1 1 0 Aminotransferase class-V Met_gamma_lyase PF06838.11 KRZ99472.1 - 0.085 11.4 0.0 0.12 10.8 0.0 1.2 1 0 0 1 1 1 0 Methionine gamma-lyase CLN3 PF02487.17 KRZ99473.1 - 5.2e-137 457.1 25.2 2e-136 455.2 25.2 1.7 1 1 0 1 1 1 1 CLN3 protein MFS_1 PF07690.16 KRZ99473.1 - 5.3e-05 22.3 2.3 5.3e-05 22.3 2.3 2.5 1 1 1 2 2 2 1 Major Facilitator Superfamily DAHP_synth_1 PF00793.20 KRZ99474.1 - 2.9e-108 360.9 0.0 3.4e-108 360.7 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family DUF218 PF02698.17 KRZ99475.1 - 0.0076 16.3 0.0 0.01 15.9 0.0 1.2 1 0 0 1 1 1 1 DUF218 domain HlyIII PF03006.20 KRZ99476.1 - 8.6e-53 179.3 16.0 1e-52 179.1 16.0 1.1 1 0 0 1 1 1 1 Haemolysin-III related NAT PF04768.13 KRZ99477.1 - 5.9e-43 146.5 0.1 1.8e-42 144.9 0.1 1.8 1 0 0 1 1 1 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase DUF494 PF04361.13 KRZ99477.1 - 0.24 11.3 0.8 35 4.3 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF494) Sld5 PF05916.11 KRZ99478.1 - 5.6e-21 75.1 2.5 5.6e-21 75.1 2.5 1.4 2 0 0 2 2 2 1 GINS complex protein HbrB PF08539.11 KRZ99479.1 - 1.5e-07 31.5 0.9 1.4e-06 28.4 0.9 2.6 1 1 0 1 1 1 1 HbrB-like Chitin_synth_1 PF01644.17 KRZ99480.1 - 4.4e-74 247.9 1.0 1.5e-73 246.1 0.9 1.9 2 0 0 2 2 2 1 Chitin synthase Chitin_synth_2 PF03142.15 KRZ99480.1 - 5.5e-27 94.6 3.0 8.6e-21 74.1 0.0 2.6 3 0 0 3 3 3 2 Chitin synthase Chitin_synth_1N PF08407.11 KRZ99480.1 - 4.4e-24 84.2 0.2 2e-23 82.1 0.0 2.2 2 0 0 2 2 2 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.6 KRZ99480.1 - 1.1e-05 25.4 2.5 1.1e-05 25.4 2.5 2.2 2 1 0 2 2 2 1 Glycosyl transferase family group 2 RCC1 PF00415.18 KRZ99481.1 - 1.7e-65 217.5 0.2 4.5e-09 36.8 0.0 7.4 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KRZ99481.1 - 1.3e-37 126.9 27.4 3.6e-08 33.0 0.1 7.1 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat Hira PF07569.11 KRZ99481.1 - 0.033 13.9 0.0 33 4.1 0.0 3.4 3 0 0 3 3 3 0 TUP1-like enhancer of split Kelch_6 PF13964.6 KRZ99481.1 - 0.32 11.3 2.8 59 4.2 0.2 4.1 4 0 0 4 4 4 0 Kelch motif Rcd1 PF04078.13 KRZ99482.1 - 2.7e-116 387.4 2.1 3.1e-116 387.2 2.1 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like RasGEF_N PF00618.20 KRZ99482.1 - 0.1 12.8 0.0 1.8 8.9 0.0 2.4 2 1 0 2 2 2 0 RasGEF N-terminal motif MatE PF01554.18 KRZ99483.1 - 2e-64 216.1 33.0 4.5e-36 123.9 12.2 2.4 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 KRZ99483.1 - 1.4e-06 28.4 9.6 1.4e-06 28.4 9.6 3.8 3 2 1 4 4 4 1 Polysaccharide biosynthesis C-terminal domain Rif1_N PF12231.8 KRZ99483.1 - 0.17 10.9 0.2 2.1 7.3 0.0 2.2 2 0 0 2 2 2 0 Rap1-interacting factor 1 N terminal Bystin PF05291.11 KRZ99484.1 - 4.1e-124 413.6 0.4 4.1e-124 413.6 0.4 1.7 2 0 0 2 2 2 1 Bystin Nop14 PF04147.12 KRZ99484.1 - 0.0071 14.6 13.9 0.0091 14.3 13.9 1.1 1 0 0 1 1 1 1 Nop14-like family RNA_pol_3_Rpc31 PF11705.8 KRZ99484.1 - 0.41 10.9 18.6 0.83 9.9 18.6 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DNA_pol_phi PF04931.13 KRZ99484.1 - 9.5 4.2 21.2 17 3.4 21.2 1.4 1 0 0 1 1 1 0 DNA polymerase phi PI-PLC-X PF00388.19 KRZ99485.1 - 2.2e-55 186.2 1.0 5.7e-55 184.9 0.1 2.2 3 0 0 3 3 3 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KRZ99485.1 - 3.3e-43 146.7 1.0 4.8e-43 146.1 0.3 1.7 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 KRZ99485.1 - 2.1e-07 31.2 0.0 4.3e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 C2 domain CDC48_2 PF02933.17 KRZ99485.1 - 0.14 11.9 0.0 0.53 10.1 0.0 2.0 2 0 0 2 2 2 0 Cell division protein 48 (CDC48), domain 2 FN3_7 PF18447.1 KRZ99485.1 - 0.21 11.9 1.6 12 6.3 0.1 2.7 2 0 0 2 2 2 0 Fibronectin type III domain UBX PF00789.20 KRZ99486.1 - 8.4e-08 32.3 0.0 2.1e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 UBX domain SRP14 PF02290.15 KRZ99487.1 - 2.4e-23 82.3 1.1 2.4e-23 82.3 1.1 1.5 2 0 0 2 2 2 1 Signal recognition particle 14kD protein MFS_1 PF07690.16 KRZ99488.1 - 1.4e-18 67.0 11.0 3.1e-18 65.8 11.0 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Nodulin-like PF06813.13 KRZ99488.1 - 3.7e-16 59.4 3.9 3.7e-16 59.4 3.9 1.9 2 0 0 2 2 2 1 Nodulin-like Dynamin_N PF00350.23 KRZ99489.1 - 1.5e-15 57.6 0.0 5.9e-15 55.7 0.0 2.1 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 KRZ99489.1 - 4e-11 43.0 0.0 1.4e-10 41.3 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KRZ99489.1 - 8.4e-08 32.0 0.3 4.9e-05 22.9 0.1 2.9 3 0 0 3 3 3 2 Elongation factor Tu GTP binding domain cobW PF02492.19 KRZ99489.1 - 8.1e-06 25.5 0.5 2.4e-05 24.0 0.5 1.8 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 KRZ99489.1 - 0.00046 20.4 0.2 2.2 8.5 0.0 3.4 3 0 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 KRZ99489.1 - 0.0024 17.8 1.3 0.56 10.1 0.2 2.9 2 0 0 2 2 2 2 RsgA GTPase Exo_endo_phos PF03372.23 KRZ99489.1 - 0.018 14.6 0.0 0.032 13.7 0.0 1.4 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family DUF3883 PF13020.6 KRZ99489.1 - 0.083 12.9 0.9 0.26 11.3 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3883) TsaE PF02367.17 KRZ99489.1 - 0.088 12.8 0.2 0.31 11.0 0.0 2.0 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 KRZ99489.1 - 0.094 13.3 0.0 0.48 11.0 0.0 2.3 1 0 0 1 1 1 0 AAA domain Ureidogly_lyase PF04115.12 KRZ99490.1 - 1.5e-60 204.2 0.0 1.7e-60 204.0 0.0 1.0 1 0 0 1 1 1 1 Ureidoglycolate lyase Adaptin_binding PF10199.9 KRZ99491.1 - 1.8e-10 41.5 10.1 1.8e-10 41.5 10.1 2.2 2 1 0 2 2 2 1 Alpha and gamma adaptin binding protein p34 AAA_18 PF13238.6 KRZ99491.1 - 0.0018 18.8 0.0 0.0041 17.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain Sec15 PF04091.12 KRZ99492.1 - 3.2e-92 309.3 6.1 3.2e-92 309.3 6.1 2.2 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like Proteasome PF00227.26 KRZ99494.1 - 5.1e-49 166.3 0.2 6.3e-49 166.0 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KRZ99494.1 - 9.7e-11 41.2 0.1 9.7e-11 41.2 0.1 2.4 3 0 0 3 3 3 1 Proteasome subunit A N-terminal signature MraZ PF02381.18 KRZ99494.1 - 0.035 14.1 0.0 0.14 12.2 0.0 1.9 2 0 0 2 2 2 0 MraZ protein, putative antitoxin-like Phage_CRI PF05144.14 KRZ99494.1 - 0.044 13.1 0.3 0.078 12.3 0.3 1.3 1 0 0 1 1 1 0 Phage replication protein CRI Cons_hypoth95 PF03602.15 KRZ99494.1 - 0.13 11.8 0.1 0.73 9.4 0.0 1.9 2 0 0 2 2 2 0 Conserved hypothetical protein 95 HSP70 PF00012.20 KRZ99495.1 - 4.6e-224 745.1 13.4 5.6e-224 744.8 13.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KRZ99495.1 - 1.6e-14 53.4 3.2 3.5e-13 49.1 1.8 2.4 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 KRZ99495.1 - 0.00034 21.0 0.5 0.12 12.9 0.1 3.5 3 1 0 3 3 3 1 Cell division protein FtsA FGGY_C PF02782.16 KRZ99495.1 - 0.0012 18.7 0.0 0.0021 17.8 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DUF1464 PF07318.12 KRZ99495.1 - 0.02 14.0 0.0 0.066 12.4 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1464) Halogen_Hydrol PF10112.9 KRZ99495.1 - 0.55 10.2 3.9 0.99 9.4 1.5 2.1 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein F-box PF00646.33 KRZ99496.1 - 0.87 9.5 3.3 8.9 6.3 0.9 3.6 3 1 0 3 3 3 0 F-box domain THUMP PF02926.17 KRZ99497.1 - 5.3e-21 75.2 0.7 9e-21 74.5 0.7 1.4 1 0 0 1 1 1 1 THUMP domain DUF1357 PF07094.11 KRZ99497.1 - 0.0032 17.6 2.1 0.0032 17.6 2.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1357) DUF1077 PF06417.12 KRZ99498.1 - 8.2e-48 161.3 2.1 1e-47 161.0 2.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) Vps55 PF04133.14 KRZ99499.1 - 1.7e-34 118.2 5.4 2e-34 118.0 5.4 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 CPBP PF02517.16 KRZ99499.1 - 0.18 12.2 4.8 0.66 10.4 4.8 2.0 1 1 0 1 1 1 0 CPBP intramembrane metalloprotease DUF4349 PF14257.6 KRZ99499.1 - 0.32 10.4 0.6 0.54 9.7 0.1 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4349) CAF1C_H4-bd PF12265.8 KRZ99500.1 - 3.1e-22 78.6 0.4 2.7e-21 75.6 0.6 2.6 3 0 0 3 3 3 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 KRZ99500.1 - 2e-07 31.6 1.4 0.6 11.1 0.1 6.3 6 0 0 6 6 6 2 WD domain, G-beta repeat PHD PF00628.29 KRZ99501.1 - 3.9e-10 39.4 9.7 3.9e-10 39.4 9.7 2.2 2 0 0 2 2 2 1 PHD-finger DUF600 PF04634.12 KRZ99501.1 - 0.0022 18.1 2.0 0.16 12.0 2.7 2.6 2 0 0 2 2 2 1 Protein of unknown function, DUF600 DUF3337 PF11816.8 KRZ99501.1 - 0.03 14.2 0.5 0.054 13.4 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3337) UPF0047 PF01894.17 KRZ99502.1 - 3.8e-34 117.3 0.0 4.4e-34 117.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 VASt PF16016.5 KRZ99504.1 - 1.5e-37 129.4 0.1 2.9e-37 128.4 0.1 1.6 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 KRZ99504.1 - 1.3e-25 89.4 0.0 3.1e-25 88.3 0.0 1.6 1 0 0 1 1 1 1 GRAM domain Vps51 PF08700.11 KRZ99504.1 - 0.059 13.5 2.4 0.28 11.3 2.4 2.2 1 0 0 1 1 1 0 Vps51/Vps67 MMU163 PF17119.5 KRZ99505.1 - 2.1e-20 72.9 0.5 3e-20 72.4 0.5 1.1 1 0 0 1 1 1 1 Mitochondrial protein up-regulated during meiosis AhpC-TSA PF00578.21 KRZ99506.1 - 4.7e-32 110.5 0.0 6.4e-32 110.1 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KRZ99506.1 - 2.2e-14 53.4 0.0 2.8e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 KRZ99506.1 - 4.1e-12 45.7 0.1 7e-12 45.0 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin DHHC PF01529.20 KRZ99507.1 - 4.7e-34 117.4 9.6 4.7e-34 117.4 9.6 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase FAM176 PF14851.6 KRZ99507.1 - 0.043 13.5 1.6 0.12 12.0 0.2 2.2 2 0 0 2 2 2 0 FAM176 family Cortexin PF11057.8 KRZ99507.1 - 0.8 9.6 4.2 12 5.9 2.1 2.6 2 0 0 2 2 2 0 Cortexin of kidney Proteasome PF00227.26 KRZ99508.1 - 4.1e-54 183.0 0.0 7.5e-54 182.1 0.0 1.4 2 0 0 2 2 2 1 Proteasome subunit SNAPc19 PF15497.6 KRZ99508.1 - 0.43 11.1 9.2 0.64 10.5 9.2 1.2 1 0 0 1 1 1 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 Mto2_bdg PF12808.7 KRZ99509.1 - 2.1e-05 24.7 8.7 2.1e-05 24.7 8.7 5.0 4 0 0 4 4 4 2 Micro-tubular organiser Mto1 C-term Mto2-binding region FTCD_C PF04961.12 KRZ99509.1 - 0.052 13.3 0.2 0.052 13.3 0.2 3.6 3 0 0 3 3 3 0 Formiminotransferase-cyclodeaminase ACP_PD PF04336.12 KRZ99509.1 - 0.46 10.9 9.6 0.097 13.1 1.2 3.9 4 1 0 4 4 4 0 Acyl carrier protein phosphodiesterase Spectrin_like PF18373.1 KRZ99509.1 - 0.56 10.3 7.5 0.41 10.8 0.3 4.1 2 1 0 3 3 3 0 Spectrin like domain MCC-bdg_PDZ PF10506.9 KRZ99509.1 - 1.8 8.7 0.0 1.8 8.7 0.0 5.2 7 0 0 7 7 7 0 PDZ domain of MCC-2 bdg protein for Usher syndrome HSBP1 PF06825.12 KRZ99509.1 - 2.5 8.0 15.5 2.3 8.1 0.1 5.2 5 0 0 5 5 5 0 Heat shock factor binding protein 1 Ribosomal_S15 PF00312.22 KRZ99509.1 - 7.4 6.9 15.4 1.2 9.4 0.1 4.7 4 1 0 4 4 4 0 Ribosomal protein S15 TPR_MLP1_2 PF07926.12 KRZ99509.1 - 9.3 6.3 65.6 0.038 14.1 7.8 7.2 6 2 2 8 8 8 0 TPR/MLP1/MLP2-like protein eIF2A PF08662.11 KRZ99510.1 - 6.3e-34 117.6 0.6 4.4e-30 105.0 1.3 3.7 3 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 KRZ99510.1 - 2.3e-08 33.8 0.1 5.3e-08 32.6 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ANAPC4_WD40 PF12894.7 KRZ99510.1 - 0.0096 16.2 0.1 21 5.5 0.0 3.9 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain ERbeta_N PF12497.8 KRZ99510.1 - 0.049 13.4 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Estrogen receptor beta WD40 PF00400.32 KRZ99510.1 - 0.15 13.0 0.2 1.3e+02 3.7 0.1 4.0 4 1 0 4 4 4 0 WD domain, G-beta repeat BolA PF01722.18 KRZ99511.1 - 4.1e-13 49.4 0.0 1.1e-12 48.0 0.0 1.6 1 1 0 1 1 1 1 BolA-like protein EF_assoc_1 PF08355.12 KRZ99512.1 - 9.1e-30 102.1 0.2 1.9e-29 101.0 0.2 1.6 1 0 0 1 1 1 1 EF hand associated Ras PF00071.22 KRZ99512.1 - 1.8e-26 92.7 0.0 3.1e-11 43.1 0.0 3.3 3 0 0 3 3 3 3 Ras family EF_assoc_2 PF08356.12 KRZ99512.1 - 3.1e-26 91.2 0.0 7.9e-26 89.9 0.0 1.7 1 0 0 1 1 1 1 EF hand associated Roc PF08477.13 KRZ99512.1 - 2.3e-13 50.4 0.0 0.0017 18.5 0.0 3.4 2 1 1 3 3 3 3 Ras of Complex, Roc, domain of DAPkinase EF-hand_1 PF00036.32 KRZ99512.1 - 4.9e-10 38.2 5.0 0.00012 21.3 0.1 2.9 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KRZ99512.1 - 5.3e-09 36.4 0.1 4.3e-05 23.9 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KRZ99512.1 - 1.5e-08 33.9 3.4 0.0023 17.7 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 KRZ99512.1 - 1.9e-07 30.3 3.4 0.003 17.0 1.6 2.8 2 0 0 2 2 2 2 EF hand MMR_HSR1 PF01926.23 KRZ99512.1 - 1.7e-05 24.9 0.1 0.039 14.0 0.1 3.3 2 2 0 2 2 2 2 50S ribosome-binding GTPase EF-hand_8 PF13833.6 KRZ99512.1 - 2.7e-05 23.9 4.2 0.038 13.9 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain pair Arf PF00025.21 KRZ99512.1 - 5.2e-05 22.8 0.0 0.0072 15.8 0.0 3.2 3 1 0 3 3 3 1 ADP-ribosylation factor family AAA_18 PF13238.6 KRZ99512.1 - 0.0073 16.9 0.0 1 9.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 KRZ99512.1 - 0.015 15.4 2.0 0.27 11.3 0.8 2.7 2 1 0 2 2 2 0 Dynamin family AAA_24 PF13479.6 KRZ99512.1 - 0.043 13.5 0.0 4.6 6.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain SRPRB PF09439.10 KRZ99512.1 - 0.054 12.9 0.1 1.6 8.2 0.0 2.9 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit EF-hand_4 PF12763.7 KRZ99512.1 - 0.074 13.0 0.0 0.22 11.5 0.0 1.8 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand AAA_16 PF13191.6 KRZ99512.1 - 0.089 13.2 0.0 1.7 9.0 0.0 2.5 2 1 0 2 2 2 0 AAA ATPase domain RsgA_GTPase PF03193.16 KRZ99512.1 - 0.14 12.1 0.0 7.7 6.4 0.0 2.8 2 0 0 2 2 2 0 RsgA GTPase RRS1 PF04939.12 KRZ99513.1 - 5.1e-61 205.3 5.4 6e-61 205.0 5.4 1.0 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) SWIB PF02201.18 KRZ99514.1 - 1.2e-24 86.0 0.4 1.7e-24 85.5 0.4 1.2 1 0 0 1 1 1 1 SWIB/MDM2 domain Membr_traf_MHD PF10540.9 KRZ99516.1 - 8.2e-39 133.1 0.8 2.9e-38 131.4 0.8 2.0 1 0 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.30 KRZ99516.1 - 7.9e-14 51.8 0.0 2.2e-13 50.4 0.0 1.8 1 0 0 1 1 1 1 C2 domain DUF810 PF05664.11 KRZ99516.1 - 1.2e-08 34.1 1.5 7.7e-08 31.3 0.2 2.4 2 0 0 2 2 2 1 Plant family of unknown function (DUF810) RisS_PPD PF16524.5 KRZ99516.1 - 0.1 12.9 0.1 2.5 8.4 0.0 2.7 2 0 0 2 2 2 0 Periplasmic domain of Sensor histidine kinase RisS DUF4281 PF14108.6 KRZ99516.1 - 0.11 12.9 0.3 0.22 11.9 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4281) Sin3a_C PF16879.5 KRZ99517.1 - 2.2e-80 270.4 7.3 2.2e-80 270.4 7.3 4.6 6 0 0 6 6 6 1 C-terminal domain of Sin3a protein PAH PF02671.21 KRZ99517.1 - 1.3e-51 172.5 7.1 3.3e-18 65.6 2.0 4.2 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 KRZ99517.1 - 2.4e-43 146.2 0.1 1.1e-42 144.1 0.1 2.3 1 0 0 1 1 1 1 Sin3 family co-repressor DUF2541 PF10807.8 KRZ99517.1 - 0.069 13.2 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2541) Dna2 PF08696.11 KRZ99517.1 - 0.63 9.8 13.7 0.22 11.3 1.2 3.8 3 0 0 3 3 3 0 DNA replication factor Dna2 Acetyltransf_1 PF00583.25 KRZ99518.1 - 7.2e-09 35.9 0.0 9.4e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KRZ99518.1 - 8.8e-07 28.9 0.1 1.4e-06 28.2 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KRZ99518.1 - 2.4e-06 27.4 0.0 3.9e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 KRZ99518.1 - 3.1e-05 24.3 0.0 4.6e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KRZ99518.1 - 0.00087 19.5 0.1 0.001 19.2 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain IFRD PF05004.13 KRZ99519.1 - 8.7e-23 80.9 16.3 1.1e-22 80.6 8.9 3.1 2 1 0 2 2 2 1 Interferon-related developmental regulator (IFRD) HEAT_EZ PF13513.6 KRZ99519.1 - 0.0039 17.7 0.1 0.019 15.4 0.2 2.1 2 0 0 2 2 2 1 HEAT-like repeat UNC45-central PF11701.8 KRZ99519.1 - 0.16 11.9 3.4 2.1 8.3 0.2 3.3 2 2 1 3 3 3 0 Myosin-binding striated muscle assembly central HHH_9 PF17674.1 KRZ99519.1 - 0.25 12.3 1.0 1.3 10.0 0.3 2.6 2 0 0 2 2 2 0 HHH domain IBD PF10416.9 KRZ99519.1 - 4.8 7.2 7.7 1 9.4 0.3 2.8 3 0 0 3 3 3 0 Transcription-initiator DNA-binding domain IBD HAD_2 PF13419.6 KRZ99520.1 - 2e-16 60.6 0.0 2.8e-16 60.1 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KRZ99520.1 - 8.3e-10 39.3 0.0 1.7e-07 31.7 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KRZ99520.1 - 0.079 13.4 0.0 0.11 12.9 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KRZ99520.1 - 0.12 12.5 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 HAD-hyrolase-like DUF1218 PF06749.12 KRZ99522.1 - 0.1 13.1 1.4 0.15 12.6 0.4 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1218) Gemini_mov PF01708.16 KRZ99522.1 - 1.1 9.1 2.8 0.48 10.2 0.2 1.8 2 0 0 2 2 2 0 Geminivirus putative movement protein DUF4173 PF13777.6 KRZ99522.1 - 3 7.2 10.7 0.76 9.2 5.9 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4173) DAO PF01266.24 KRZ99523.1 - 2.3e-53 182.0 0.0 3.1e-53 181.6 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 KRZ99523.1 - 8.3e-41 138.8 0.1 2.5e-40 137.2 0.1 1.8 2 0 0 2 2 2 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 KRZ99523.1 - 9.8e-14 51.2 1.8 4e-13 49.3 1.8 1.8 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KRZ99523.1 - 7.2e-11 42.1 1.7 2.1e-06 27.3 0.2 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase GIDA PF01134.22 KRZ99523.1 - 1e-05 24.8 0.7 0.0075 15.4 0.2 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.17 KRZ99523.1 - 0.00019 20.8 0.3 0.075 12.3 0.0 2.2 2 0 0 2 2 2 2 Thi4 family FAD_binding_3 PF01494.19 KRZ99523.1 - 0.00036 19.9 0.6 0.0017 17.6 0.6 1.9 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KRZ99523.1 - 0.00066 19.0 0.1 0.005 16.1 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KRZ99523.1 - 0.0014 17.5 1.1 0.0017 17.2 0.2 1.6 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 KRZ99523.1 - 0.0022 18.2 0.8 0.0059 16.8 0.5 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 KRZ99523.1 - 0.062 12.6 0.0 0.17 11.2 0.0 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 KRZ99523.1 - 0.07 12.4 0.0 0.16 11.2 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 KRZ99523.1 - 0.092 12.6 0.8 0.31 10.9 0.8 1.9 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 KRZ99523.1 - 0.099 11.7 0.1 0.16 11.0 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein UBA_4 PF14555.6 KRZ99524.1 - 4.7e-15 55.1 0.0 4.7e-15 55.1 0.0 2.0 3 0 0 3 3 3 1 UBA-like domain UBX PF00789.20 KRZ99524.1 - 3.6e-08 33.5 0.0 2.5e-07 30.8 0.0 2.5 1 1 0 1 1 1 1 UBX domain DUF1940 PF09155.10 KRZ99524.1 - 0.04 14.0 0.3 0.13 12.3 0.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1940) SdpA PF17418.2 KRZ99524.1 - 0.049 13.5 0.1 0.43 10.4 0.0 2.2 2 0 0 2 2 2 0 Sporulation delaying protein SdpA Mrpl_C PF18502.1 KRZ99524.1 - 1.1 9.6 6.6 0.25 11.6 2.8 1.9 2 0 0 2 2 2 0 54S ribosomal protein L8 C-terminal domain Usp PF00582.26 KRZ99525.1 - 3.7e-21 76.1 0.0 8.3e-21 75.0 0.0 1.6 1 0 0 1 1 1 1 Universal stress protein family STALD PF18185.1 KRZ99525.1 - 0.031 13.6 0.0 0.065 12.6 0.0 1.5 1 0 0 1 1 1 0 Sir2- and TIR-associating SLOG family zf-RING_5 PF14634.6 KRZ99526.1 - 0.002 18.1 0.7 0.002 18.1 0.7 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KRZ99526.1 - 0.0051 16.8 0.9 0.0098 15.9 0.1 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KRZ99526.1 - 0.0075 16.1 1.1 0.0075 16.1 1.1 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KRZ99526.1 - 0.014 15.3 0.1 0.039 13.8 0.1 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KRZ99526.1 - 0.034 14.3 0.1 0.093 12.9 0.1 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 KRZ99526.1 - 0.04 13.8 0.3 0.04 13.8 0.3 1.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KRZ99526.1 - 0.093 13.1 0.8 0.093 13.1 0.8 1.8 2 0 0 2 2 2 0 Ring finger domain DUF1126 PF06565.12 KRZ99526.1 - 0.14 12.0 0.3 0.31 10.9 0.3 1.5 1 0 0 1 1 1 0 DUF1126 PH-like domain Fibrillarin PF01269.17 KRZ99527.1 - 5.2e-105 349.6 0.0 6.4e-105 349.3 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 KRZ99527.1 - 3e-06 27.1 0.1 6.2e-06 26.1 0.1 1.4 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit FtsJ PF01728.19 KRZ99527.1 - 0.0074 16.4 0.0 0.0095 16.1 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltr_RsmB-F PF01189.17 KRZ99527.1 - 0.058 13.0 0.0 0.12 12.0 0.0 1.5 2 0 0 2 2 2 0 16S rRNA methyltransferase RsmB/F PCMT PF01135.19 KRZ99527.1 - 0.077 12.7 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Nuc_sug_transp PF04142.15 KRZ99528.1 - 1.2e-14 54.2 3.6 1.2e-14 54.2 3.6 1.8 2 1 0 2 2 2 1 Nucleotide-sugar transporter EamA PF00892.20 KRZ99528.1 - 9.3e-09 35.6 34.9 2.7e-06 27.6 5.1 3.6 4 1 0 4 4 4 2 EamA-like transporter family TPT PF03151.16 KRZ99528.1 - 3.4e-07 29.9 0.2 3.4e-07 29.9 0.2 2.1 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.11 KRZ99528.1 - 4.9e-07 29.3 20.6 8.9e-07 28.4 19.6 1.8 2 0 0 2 2 2 1 UAA transporter family PUNUT PF16913.5 KRZ99528.1 - 0.00092 18.5 19.4 0.0021 17.3 19.4 1.7 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport UMP1 PF05348.11 KRZ99529.1 - 2.9e-40 137.1 0.1 3.6e-40 136.9 0.1 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 GYF PF02213.16 KRZ99530.1 - 5.9e-15 54.7 0.2 1.3e-14 53.6 0.2 1.6 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 KRZ99530.1 - 0.013 15.3 0.0 0.035 13.9 0.0 1.8 1 0 0 1 1 1 0 GYF domain 2 ACT_7 PF13840.6 KRZ99531.1 - 1.1e-25 89.2 1.6 7.3e-13 48.1 0.1 2.3 2 0 0 2 2 2 2 ACT domain Castor1_N PF18700.1 KRZ99531.1 - 0.015 15.1 0.5 1.3 8.9 0.0 3.2 3 0 0 3 3 3 0 Cytosolic arginine sensor for mTORC1 subunit 1 N-terminal domain Vps5 PF09325.10 KRZ99532.1 - 2.8e-83 279.1 15.1 4.6e-83 278.4 15.1 1.3 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 KRZ99532.1 - 1e-22 80.2 0.1 4.3e-22 78.2 0.1 2.1 1 0 0 1 1 1 1 PX domain DUF16 PF01519.16 KRZ99532.1 - 3e-05 24.4 5.3 0.00088 19.7 1.2 3.1 2 0 0 2 2 2 2 Protein of unknown function DUF16 DUF1664 PF07889.12 KRZ99532.1 - 0.013 15.5 1.4 4.2 7.4 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Laminin_II PF06009.12 KRZ99532.1 - 0.47 10.5 6.3 0.93 9.5 0.7 2.6 2 0 0 2 2 2 0 Laminin Domain II ChaC PF04752.12 KRZ99533.1 - 6.9e-50 169.6 0.4 1.3e-49 168.7 0.4 1.4 1 1 0 1 1 1 1 ChaC-like protein Nha1_C PF08619.10 KRZ99534.1 - 9.5e-69 232.8 39.8 5.5e-68 230.3 39.8 1.9 1 1 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus Na_H_Exchanger PF00999.21 KRZ99534.1 - 2.6e-67 227.3 24.4 3.2e-67 227.0 24.4 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Colicin_E5 PF12106.8 KRZ99534.1 - 0.0058 16.9 0.1 2.4 8.5 0.0 2.9 2 0 0 2 2 2 2 Colicin E5 ribonuclease domain GAGA_bind PF06217.12 KRZ99534.1 - 0.72 10.1 6.4 4 7.6 0.1 2.4 2 1 0 2 2 2 0 GAGA binding protein-like family Aminotran_3 PF00202.21 KRZ99535.1 - 1.1e-119 399.7 0.0 1.3e-119 399.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KRZ99535.1 - 4e-05 23.0 0.0 5.8e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KRZ99535.1 - 0.00085 18.7 0.0 0.0022 17.3 0.0 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase RNR_inhib PF08591.10 KRZ99536.1 - 1.8e-09 38.8 0.5 9.8e-08 33.3 0.5 2.3 1 1 0 1 1 1 1 Ribonucleotide reductase inhibitor SUR7 PF06687.12 KRZ99537.1 - 3.3e-26 92.3 6.9 4.8e-26 91.7 6.9 1.2 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.8 KRZ99537.1 - 0.056 13.4 2.6 0.12 12.3 2.6 1.5 1 0 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 TMEM220 PF15071.6 KRZ99538.1 - 0.76 10.6 3.6 0.95 10.2 2.0 1.9 2 0 0 2 2 2 0 Transmembrane family 220, helix Cys_Met_Meta_PP PF01053.20 KRZ99539.1 - 5.3e-143 476.2 0.0 6e-143 476.0 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KRZ99539.1 - 4e-10 39.4 0.0 6.5e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KRZ99539.1 - 1.4e-09 37.8 0.1 2.4e-09 37.0 0.1 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 KRZ99539.1 - 1.7e-09 37.1 0.6 2.5e-09 36.6 0.6 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Met_gamma_lyase PF06838.11 KRZ99539.1 - 0.00015 20.5 0.2 0.00022 19.9 0.2 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase GDC-P PF02347.16 KRZ99539.1 - 0.013 14.3 0.0 0.019 13.8 0.0 1.1 1 0 0 1 1 1 0 Glycine cleavage system P-protein Beta_elim_lyase PF01212.21 KRZ99539.1 - 0.018 14.3 0.0 0.025 13.9 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase SepSecS PF05889.13 KRZ99539.1 - 0.078 11.7 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS MUG113 PF13455.6 KRZ99540.1 - 2e-09 38.0 1.9 2.2e-08 34.6 1.9 2.4 1 1 0 1 1 1 1 Meiotically up-regulated gene 113 T5orf172 PF10544.9 KRZ99540.1 - 1.4e-07 32.0 2.2 2.8e-05 24.6 2.2 3.0 1 1 0 1 1 1 1 T5orf172 domain zf-primase PF09329.11 KRZ99540.1 - 0.11 12.3 3.9 0.28 11.0 3.2 2.1 2 1 0 2 2 2 0 Primase zinc finger DEAD PF00270.29 KRZ99541.1 - 2.7e-36 125.0 0.1 5.1e-36 124.1 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KRZ99541.1 - 2.7e-26 92.1 0.2 3.7e-25 88.4 0.1 2.6 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KRZ99541.1 - 2.9e-09 37.2 0.0 6.2e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 KRZ99541.1 - 0.02 14.3 0.0 0.057 12.7 0.1 1.7 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit DUF1641 PF07849.11 KRZ99542.1 - 0.0069 16.3 0.2 0.017 15.0 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1641) ComZ PF10815.8 KRZ99542.1 - 0.41 10.7 3.8 0.45 10.6 0.1 2.5 3 0 0 3 3 3 0 ComZ P5CR_dimer PF14748.6 KRZ99543.1 - 3.7e-34 117.1 2.6 3.7e-34 117.1 2.6 1.9 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 KRZ99543.1 - 5.3e-15 55.8 0.0 1.1e-14 54.8 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.23 KRZ99543.1 - 3.2e-05 24.0 0.1 0.00012 22.1 0.1 1.8 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 KRZ99543.1 - 8.2e-05 22.3 0.0 0.00014 21.5 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pribosyltran_N PF13793.6 KRZ99543.1 - 0.00034 20.5 0.1 0.00063 19.7 0.1 1.4 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Fer4_14 PF13394.6 KRZ99543.1 - 0.0058 16.8 0.0 0.0093 16.1 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain IlvN PF07991.12 KRZ99543.1 - 0.012 15.2 0.0 0.029 13.9 0.0 1.7 1 1 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain JmjC PF02373.22 KRZ99544.1 - 6.6e-41 139.3 1.8 1.3e-40 138.4 0.1 2.4 2 0 0 2 2 2 1 JmjC domain, hydroxylase JmjN PF02375.17 KRZ99544.1 - 7.5e-12 45.0 2.3 8.5e-12 44.8 0.3 2.3 2 0 0 2 2 2 1 jmjN domain PHD PF00628.29 KRZ99544.1 - 8.5e-12 44.8 5.4 8.5e-12 44.8 5.4 2.1 2 0 0 2 2 2 1 PHD-finger ARID PF01388.21 KRZ99544.1 - 7.4e-06 26.6 0.0 2.1e-05 25.1 0.0 1.8 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain PHD_2 PF13831.6 KRZ99544.1 - 0.0014 18.1 0.6 0.0014 18.1 0.6 1.9 2 0 0 2 2 2 1 PHD-finger C1_2 PF03107.16 KRZ99544.1 - 0.037 14.4 10.1 0.94 9.9 4.7 3.0 2 0 0 2 2 2 0 C1 domain zf-HC5HC2H PF13771.6 KRZ99544.1 - 0.15 12.3 0.9 0.84 9.9 0.1 2.4 2 0 0 2 2 2 0 PHD-like zinc-binding domain C1_1 PF00130.22 KRZ99544.1 - 0.9 9.5 3.6 1.7 8.6 0.4 2.7 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.6 KRZ99544.1 - 3.9 7.5 8.5 0.4 10.7 2.6 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RanBP PF00641.18 KRZ99544.1 - 5 6.5 8.2 7.2 6.0 0.2 2.9 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others ATP-synt_ab PF00006.25 KRZ99545.1 - 3.4e-62 209.9 0.0 5.1e-62 209.3 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 KRZ99545.1 - 1e-23 83.6 0.8 3.1e-23 82.1 0.8 1.9 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain ATPase PF06745.13 KRZ99545.1 - 0.0017 17.7 0.2 0.0031 16.9 0.2 1.4 1 0 0 1 1 1 1 KaiC NB-ARC PF00931.22 KRZ99545.1 - 0.012 14.9 0.6 0.076 12.2 0.1 2.0 2 0 0 2 2 2 0 NB-ARC domain RsgA_GTPase PF03193.16 KRZ99545.1 - 0.042 13.8 0.1 0.086 12.7 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase NACHT PF05729.12 KRZ99545.1 - 0.042 13.8 0.2 0.12 12.3 0.0 1.8 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.6 KRZ99545.1 - 0.11 12.8 0.1 0.34 11.3 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.22 KRZ99545.1 - 0.12 12.8 0.0 0.23 11.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.6 KRZ99545.1 - 0.13 12.6 0.6 0.48 10.8 0.2 2.0 2 0 0 2 2 2 0 AAA domain T3SS_ATPase_C PF18269.1 KRZ99545.1 - 0.14 12.1 0.3 0.83 9.6 0.3 2.1 1 1 0 1 1 1 0 T3SS EscN ATPase C-terminal domain Peptidase_M48 PF01435.18 KRZ99546.1 - 1.6e-47 161.8 0.0 2.1e-47 161.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M48_N PF16491.5 KRZ99546.1 - 7.1e-42 143.4 8.4 7.1e-42 143.4 8.4 1.8 2 1 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices SprT-like PF10263.9 KRZ99546.1 - 0.029 14.2 0.1 0.048 13.5 0.1 1.4 1 0 0 1 1 1 0 SprT-like family PDCD9 PF07147.12 KRZ99546.1 - 0.19 10.9 0.0 0.26 10.5 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S30 (PDCD9) LUC7 PF03194.15 KRZ99547.1 - 3.7e-57 193.9 9.4 4.4e-57 193.6 9.4 1.0 1 0 0 1 1 1 1 LUC7 N_terminus GAS PF13851.6 KRZ99547.1 - 0.0023 17.3 5.9 0.0039 16.6 5.9 1.4 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Imm49 PF15575.6 KRZ99547.1 - 0.027 14.3 0.2 0.051 13.3 0.0 1.5 2 0 0 2 2 2 0 Immunity protein 49 FAM24 PF15193.6 KRZ99547.1 - 0.053 14.3 0.3 0.12 13.2 0.3 1.7 1 0 0 1 1 1 0 FAM24 family MscS_porin PF12795.7 KRZ99547.1 - 0.22 11.1 2.5 0.34 10.4 2.5 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain UPF0242 PF06785.11 KRZ99547.1 - 0.22 11.6 7.3 0.38 10.8 7.3 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Sod_Fe_N PF00081.22 KRZ99547.1 - 1.5 9.3 5.8 1.4 9.5 2.7 2.4 2 1 0 2 2 2 0 Iron/manganese superoxide dismutases, alpha-hairpin domain F-box-like PF12937.7 KRZ99548.1 - 1e-09 38.1 0.1 2.3e-09 37.0 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KRZ99548.1 - 0.00035 20.4 0.7 0.00082 19.2 0.7 1.7 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KRZ99548.1 - 0.1 12.5 0.0 0.29 11.0 0.0 1.8 1 0 0 1 1 1 0 F-box Glyco_hydro_72 PF03198.14 KRZ99549.1 - 2.5e-18 66.4 0.2 3.9e-18 65.8 0.2 1.3 1 0 0 1 1 1 1 Glucanosyltransferase Cys_Met_Meta_PP PF01053.20 KRZ99550.1 - 1.1e-23 83.4 0.1 7.6e-23 80.7 0.1 1.8 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DUF3589 PF12141.8 KRZ99551.1 - 9.7e-191 634.6 2.8 9.7e-191 634.6 2.8 1.4 2 0 0 2 2 2 1 Beta-mannosyltransferases Abhydrolase_1 PF00561.20 KRZ99552.1 - 3e-19 69.7 0.0 2.6e-18 66.6 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KRZ99552.1 - 5.3e-12 46.8 0.0 7e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KRZ99552.1 - 6.4e-07 28.9 0.0 8.7e-06 25.2 0.0 2.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KRZ99552.1 - 0.00013 22.2 0.0 0.0002 21.5 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Esterase PF00756.20 KRZ99552.1 - 0.044 13.4 0.0 0.064 12.9 0.0 1.3 1 0 0 1 1 1 0 Putative esterase DLH PF01738.18 KRZ99552.1 - 0.15 11.6 0.0 0.56 9.7 0.0 1.8 2 0 0 2 2 2 0 Dienelactone hydrolase family AA_permease PF00324.21 KRZ99553.1 - 2.1e-123 412.4 34.2 2.6e-123 412.2 34.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KRZ99553.1 - 3.9e-33 114.9 36.3 4.6e-33 114.7 36.3 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4781 PF16013.5 KRZ99553.1 - 2.6 6.8 7.0 0.13 11.0 0.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4781) Metallophos PF00149.28 KRZ99554.1 - 2.3e-19 70.7 2.5 3.8e-19 70.0 2.5 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 KRZ99554.1 - 1e-18 67.7 2.7 2.8e-18 66.2 1.8 2.3 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain Metallophos_C PF14008.6 KRZ99554.1 - 4.8e-18 65.8 0.1 1.3e-17 64.4 0.1 1.8 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Flocculin_t3 PF13928.6 KRZ99554.1 - 8.6e-11 42.2 15.2 2.7e-10 40.6 15.2 1.9 1 0 0 1 1 1 1 Flocculin type 3 repeat PhoD_N PF16655.5 KRZ99554.1 - 0.00088 19.8 0.1 0.0026 18.2 0.1 1.8 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain fn3 PF00041.21 KRZ99554.1 - 0.001 19.3 0.9 0.0037 17.6 0.9 1.9 1 0 0 1 1 1 1 Fibronectin type III domain DUF2369 PF10179.9 KRZ99554.1 - 0.058 13.8 0.2 0.25 11.7 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2369) LIP PF03583.14 KRZ99555.1 - 1.7e-89 300.0 0.1 2.1e-89 299.7 0.1 1.1 1 0 0 1 1 1 1 Secretory lipase Peptidase_S9 PF00326.21 KRZ99555.1 - 0.0007 19.1 0.1 0.66 9.4 0.1 2.5 2 1 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KRZ99555.1 - 0.0058 16.3 0.0 0.59 9.7 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold ADH_zinc_N PF00107.26 KRZ99556.1 - 4.3e-07 30.0 0.0 7.4e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KRZ99556.1 - 7.6e-05 22.6 0.0 0.00013 21.8 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Eno-Rase_NADH_b PF12242.8 KRZ99556.1 - 0.055 13.2 0.6 0.17 11.6 0.3 2.0 1 1 1 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase GST_N_3 PF13417.6 KRZ99557.1 - 4.7e-13 49.3 0.0 1.1e-12 48.1 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KRZ99557.1 - 1.9e-09 37.7 0.0 3.4e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KRZ99557.1 - 8.8e-06 26.0 0.1 5e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KRZ99557.1 - 0.00013 22.1 0.2 0.00024 21.2 0.2 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin2_C PF04399.13 KRZ99557.1 - 0.00025 20.9 0.1 0.00042 20.2 0.1 1.3 1 0 0 1 1 1 1 Glutaredoxin 2, C terminal domain GST_C_2 PF13410.6 KRZ99557.1 - 0.17 11.9 0.0 0.29 11.2 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain AA_permease PF00324.21 KRZ99558.1 - 3.1e-122 408.6 54.3 3.7e-122 408.3 54.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KRZ99558.1 - 3.5e-26 92.0 61.4 8.6e-26 90.7 61.3 1.6 1 1 0 1 1 1 1 Amino acid permease S-methyl_trans PF02574.16 KRZ99559.1 - 3.9e-62 210.5 0.0 4.5e-62 210.3 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase DUF2796 PF10986.8 KRZ99559.1 - 0.054 13.5 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) FAD_binding_7 PF03441.14 KRZ99560.1 - 3.5e-80 268.3 1.5 6.6e-80 267.3 1.5 1.5 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 KRZ99560.1 - 1.8e-30 106.1 0.0 2.9e-30 105.4 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase ABC_sub_bind PF04392.12 KRZ99560.1 - 0.11 11.7 0.1 0.18 11.0 0.1 1.2 1 0 0 1 1 1 0 ABC transporter substrate binding protein MFS_1 PF07690.16 KRZ99561.1 - 8.6e-13 47.9 6.5 1e-12 47.7 6.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 KRZ99561.1 - 6.5e-05 21.7 1.9 8.2e-05 21.3 1.9 1.1 1 0 0 1 1 1 1 MFS/sugar transport protein Sugar_tr PF00083.24 KRZ99561.1 - 0.00079 18.4 4.2 0.0012 17.8 4.2 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter Ser_hydrolase PF06821.13 KRZ99561.1 - 0.074 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase DUF5423 PF17461.2 KRZ99561.1 - 2.4 6.9 6.9 1.6 7.5 1.8 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5423) TMEM234 PF10639.9 KRZ99562.1 - 0.71 9.9 4.5 0.17 11.9 0.3 2.2 3 0 0 3 3 3 0 Putative transmembrane family 234 LtrA PF06772.11 KRZ99563.1 - 5.5e-32 111.4 7.1 7.5e-32 110.9 7.1 1.0 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) Y_phosphatase PF00102.27 KRZ99564.1 - 0.16 11.5 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase MFS_1 PF07690.16 KRZ99565.1 - 2.3e-39 135.3 25.8 2.3e-39 135.3 25.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KRZ99565.1 - 2.7e-10 39.7 24.4 8e-10 38.2 24.4 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 KRZ99565.1 - 0.0005 18.6 0.9 0.00082 17.9 0.9 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 KRZ99565.1 - 0.0018 17.6 0.3 0.0018 17.6 0.3 2.5 2 1 1 3 3 3 2 Uncharacterised MFS-type transporter YbfB SNARE PF05739.19 KRZ99565.1 - 0.43 10.6 4.9 6.9 6.8 0.6 3.0 2 0 0 2 2 2 0 SNARE domain SieB PF14163.6 KRZ99565.1 - 0.58 9.6 2.1 1.9 7.9 0.1 2.7 3 0 0 3 3 3 0 Super-infection exclusion protein B His_Phos_1 PF00300.22 KRZ99566.1 - 1.6e-05 24.7 1.5 6.2e-05 22.8 1.5 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) PLA2_B PF01735.18 KRZ99567.1 - 4.5e-194 645.4 4.8 6.8e-194 644.8 4.8 1.3 1 0 0 1 1 1 1 Lysophospholipase catalytic domain IBR PF01485.21 KRZ99567.1 - 0.0012 19.0 2.0 0.0029 17.8 2.0 1.6 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain Ecl1 PF12855.7 KRZ99567.1 - 0.024 15.8 8.2 0.024 15.8 8.2 2.4 2 0 0 2 2 2 0 ECL1/2/3 zinc binding proteins DUF913 PF06025.12 KRZ99567.1 - 0.082 11.9 7.0 1.8 7.5 3.1 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) FAM209 PF15206.6 KRZ99567.1 - 0.21 11.4 0.4 0.56 10.0 0.4 1.6 1 0 0 1 1 1 0 FAM209 family DUF1645 PF07816.11 KRZ99567.1 - 3.5 8.2 34.1 6.7 7.2 18.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) Macoilin PF09726.9 KRZ99567.1 - 5.2 5.5 33.1 1.3 7.5 7.3 2.1 2 0 0 2 2 2 0 Macoilin family SpoIIIAH PF12685.7 KRZ99567.1 - 5.8 6.7 16.7 1.7 8.4 6.8 2.3 2 0 0 2 2 2 0 SpoIIIAH-like protein Kei1 PF08552.11 KRZ99567.1 - 7.2 6.4 9.2 7.9 6.3 4.3 2.4 2 0 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 WD40 PF00400.32 KRZ99568.1 - 1.4e-49 165.0 21.3 4.1e-07 30.6 0.2 11.6 11 0 0 11 11 11 8 WD domain, G-beta repeat Utp12 PF04003.12 KRZ99568.1 - 9.7e-20 70.9 0.6 1.9e-19 69.9 0.6 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 KRZ99568.1 - 1.1e-18 67.3 3.3 0.02 15.2 0.0 9.8 4 2 6 10 10 10 7 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KRZ99568.1 - 2.1e-09 37.2 4.3 0.00016 21.1 0.1 5.7 5 1 0 5 5 5 1 WD40-like domain Nup160 PF11715.8 KRZ99568.1 - 2e-08 33.3 0.0 0.016 13.9 0.0 4.6 4 0 0 4 4 4 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KRZ99568.1 - 3.2e-06 26.4 1.2 1.1 8.1 0.0 5.5 4 1 1 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PALB2_WD40 PF16756.5 KRZ99568.1 - 0.00028 19.9 4.8 2.3 7.1 0.1 4.7 4 1 1 5 5 5 2 Partner and localizer of BRCA2 WD40 domain Hira PF07569.11 KRZ99568.1 - 0.00054 19.7 0.1 1.3 8.7 0.0 3.9 4 0 0 4 4 4 2 TUP1-like enhancer of split DUF1310 PF07006.11 KRZ99568.1 - 0.024 14.6 0.1 0.088 12.8 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1310) Med15_fungi PF05397.12 KRZ99569.1 - 5.3e-37 126.5 6.6 5.3e-37 126.5 6.6 6.7 6 2 3 9 9 9 1 Mediator complex subunit 15 Gal11_ABD1 PF18535.1 KRZ99569.1 - 2.5e-26 91.6 15.9 2.5e-26 91.6 15.9 6.4 8 1 0 8 8 8 1 Gal11 activator-binding domain (ABD1) KIX_2 PF16987.5 KRZ99569.1 - 6.3e-19 67.8 0.4 6.3e-19 67.8 0.4 4.1 4 1 1 5 5 5 1 KIX domain LMWPc PF01451.21 KRZ99570.1 - 3.5e-33 115.0 0.0 3.9e-33 114.8 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Not3 PF04065.15 KRZ99571.1 - 7.3e-78 261.2 32.4 2.3e-77 259.5 32.4 1.9 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 KRZ99571.1 - 6.9e-40 136.2 8.2 6.9e-40 136.2 8.2 3.0 3 0 0 3 3 3 1 NOT2 / NOT3 / NOT5 family Trypan_PARP PF05887.11 KRZ99571.1 - 0.43 10.5 21.3 0.067 13.2 16.7 1.9 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) YlqD PF11068.8 KRZ99571.1 - 1.2 9.5 18.1 1.2 9.5 1.4 3.8 3 0 0 3 3 3 0 YlqD protein Lin-8 PF03353.15 KRZ99571.1 - 1.8 8.0 45.2 0.14 11.7 22.3 2.9 2 1 1 3 3 3 0 Ras-mediated vulval-induction antagonist Opy2 PF09463.10 KRZ99572.1 - 4.6e-09 36.4 18.2 6.9e-09 35.9 18.2 1.3 1 0 0 1 1 1 1 Opy2 protein Yip1 PF04893.17 KRZ99572.1 - 0.12 12.0 0.5 0.19 11.5 0.5 1.2 1 0 0 1 1 1 0 Yip1 domain zf-ANAPC11 PF12861.7 KRZ99572.1 - 0.9 9.6 5.6 1.6 8.8 5.6 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Transketolase_N PF00456.21 KRZ99573.1 - 4.6e-160 532.1 0.0 6e-160 531.7 0.0 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 KRZ99573.1 - 7.6e-47 159.3 0.0 1.2e-46 158.7 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KRZ99573.1 - 1.8e-13 50.5 0.0 3.5e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 KRZ99573.1 - 0.00015 21.1 0.0 0.00064 19.0 0.0 1.8 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase Beta_elim_lyase PF01212.21 KRZ99573.1 - 0.0088 15.4 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase ADH_N PF08240.12 KRZ99574.1 - 7.7e-29 99.8 0.2 1.5e-28 98.9 0.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KRZ99574.1 - 3e-25 88.7 0.2 5.3e-25 87.9 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KRZ99574.1 - 7.3e-05 23.8 0.0 0.00013 23.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FA_desaturase PF00487.24 KRZ99575.1 - 7.4e-18 65.3 15.0 7.4e-18 65.3 15.0 1.5 2 0 0 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 KRZ99575.1 - 1.7e-14 53.7 0.0 3.7e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain CBS PF00571.28 KRZ99576.1 - 2.7e-19 69.4 1.0 4e-05 24.0 0.0 5.3 5 0 0 5 5 5 5 CBS domain 3-HAO PF06052.12 KRZ99577.1 - 1.1e-64 216.6 0.0 1.3e-64 216.4 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.11 KRZ99577.1 - 1e-07 31.6 0.0 1.6e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Cupin domain DZR PF12773.7 KRZ99577.1 - 0.0029 17.6 1.2 0.013 15.5 1.2 2.0 1 1 0 1 1 1 1 Double zinc ribbon AraC_binding PF02311.19 KRZ99577.1 - 0.036 14.0 0.1 0.07 13.0 0.1 1.6 1 1 0 1 1 1 0 AraC-like ligand binding domain Cupin_3 PF05899.12 KRZ99577.1 - 0.07 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Cupin_1 PF00190.22 KRZ99577.1 - 0.084 12.5 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Cupin Nudix_N_2 PF14803.6 KRZ99577.1 - 0.18 11.7 2.6 7 6.7 0.1 2.7 2 0 0 2 2 2 0 Nudix N-terminal ADK_lid PF05191.14 KRZ99577.1 - 0.26 11.3 3.0 8.5 6.5 0.1 2.9 3 0 0 3 3 3 0 Adenylate kinase, active site lid zinc_ribbon_2 PF13240.6 KRZ99577.1 - 0.65 9.8 0.1 0.65 9.8 0.1 2.9 3 1 0 3 3 3 0 zinc-ribbon domain MTP18 PF10558.9 KRZ99578.1 - 5.3e-70 234.8 0.0 6.3e-70 234.6 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) DUF2407_C PF13373.6 KRZ99579.1 - 2.8e-44 150.7 0.0 4.4e-44 150.1 0.0 1.3 1 0 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.9 KRZ99579.1 - 2.4e-22 79.4 0.2 6.1e-22 78.2 0.1 1.8 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 KRZ99579.1 - 0.025 14.3 0.0 0.069 12.9 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin family Acetyltransf_11 PF13720.6 KRZ99579.1 - 0.038 14.5 0.1 0.087 13.3 0.1 1.6 1 0 0 1 1 1 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Rad60-SLD_2 PF13881.6 KRZ99579.1 - 0.13 12.3 0.3 0.37 10.9 0.3 1.7 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Mito_carr PF00153.27 KRZ99580.1 - 1.6e-61 204.2 2.0 1.7e-22 79.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RIIa PF02197.17 KRZ99580.1 - 0.15 11.7 0.0 9.6 6.0 0.0 2.4 2 0 0 2 2 2 0 Regulatory subunit of type II PKA R-subunit DUF1741 PF08427.10 KRZ99581.1 - 3.6e-05 23.5 6.9 0.00034 20.4 6.9 2.5 1 1 0 1 1 1 1 Domain of unknown function (DUF1741) DPPIV_N PF00930.21 KRZ99582.1 - 4.5e-71 239.5 11.3 4.5e-71 239.5 11.3 1.9 2 0 0 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 KRZ99582.1 - 1.9e-42 145.2 0.5 4.4e-42 144.0 0.5 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 KRZ99582.1 - 2.6e-07 30.5 0.0 1.4e-06 28.2 0.0 1.9 2 0 0 2 2 2 1 Putative esterase Abhydrolase_6 PF12697.7 KRZ99582.1 - 0.0078 16.8 0.0 0.058 14.0 0.0 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KRZ99582.1 - 0.023 14.3 0.0 0.1 12.2 0.0 2.0 1 1 1 2 2 2 0 alpha/beta hydrolase fold Noc2 PF03715.13 KRZ99583.1 - 4.3e-130 433.3 6.1 1e-129 432.1 6.1 1.7 1 0 0 1 1 1 1 Noc2p family Nop14 PF04147.12 KRZ99583.1 - 3.1e-06 25.8 1.0 3.1e-06 25.8 1.0 3.0 2 2 1 3 3 3 1 Nop14-like family CPP1-like PF11833.8 KRZ99583.1 - 0.052 13.2 1.2 1.1 8.9 0.6 2.6 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like CodY PF06018.14 KRZ99583.1 - 0.062 12.8 0.7 2.1 7.8 0.1 2.9 2 0 0 2 2 2 0 CodY GAF-like domain Zn_clus PF00172.18 KRZ99584.1 - 0.0001 22.3 8.6 0.00022 21.3 8.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-RING_2 PF13639.6 KRZ99585.1 - 1.5e-10 41.2 8.8 2.8e-10 40.3 8.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KRZ99585.1 - 2e-06 27.4 4.5 2e-06 27.4 4.5 2.3 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KRZ99585.1 - 5e-06 26.3 9.0 9.1e-06 25.4 9.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KRZ99585.1 - 8.1e-06 26.0 9.2 2.6e-05 24.4 9.2 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KRZ99585.1 - 1.4e-05 24.9 8.3 1.4e-05 24.9 8.3 1.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KRZ99585.1 - 8.6e-05 22.5 8.2 0.00021 21.2 8.2 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KRZ99585.1 - 0.00019 21.2 6.4 0.00038 20.2 6.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KRZ99585.1 - 0.00053 19.9 7.3 0.0012 18.7 7.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KRZ99585.1 - 0.0016 18.5 2.6 0.0035 17.3 2.6 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.8 KRZ99585.1 - 0.0057 16.5 4.4 0.014 15.2 4.4 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 KRZ99585.1 - 0.033 14.0 10.2 0.65 9.9 10.6 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 KRZ99585.1 - 0.056 13.1 3.3 0.11 12.2 3.3 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Prok-RING_1 PF14446.6 KRZ99585.1 - 0.063 13.2 4.5 0.1 12.5 1.5 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 DUF4876 PF16215.5 KRZ99585.1 - 0.16 12.0 6.1 0.058 13.4 1.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4876) ABC2_membrane_3 PF12698.7 KRZ99585.1 - 0.33 10.0 9.2 1.7 7.7 9.2 2.2 1 1 0 1 1 1 0 ABC-2 family transporter protein FANCL_C PF11793.8 KRZ99585.1 - 3.2 8.0 8.1 6.5 7.0 6.8 2.3 2 1 0 2 2 1 0 FANCL C-terminal domain RNA_pol_Rpb2_6 PF00562.28 KRZ99586.1 - 1e-125 419.9 0.0 1e-125 419.9 0.0 1.4 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KRZ99586.1 - 2.5e-58 196.9 0.4 3.6e-58 196.4 0.4 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 KRZ99586.1 - 2.6e-40 138.1 2.7 6.2e-40 136.9 2.7 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 KRZ99586.1 - 1.7e-33 114.8 0.2 5.2e-33 113.3 0.2 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.13 KRZ99586.1 - 6e-24 84.1 0.4 2.2e-23 82.3 0.2 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 KRZ99586.1 - 2.3e-18 66.1 0.0 4.5e-18 65.2 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 KRZ99586.1 - 4.5e-14 52.8 1.4 1.3e-13 51.3 1.4 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 TraI_2_C PF07515.11 KRZ99586.1 - 0.079 12.9 0.2 0.18 11.7 0.2 1.5 1 0 0 1 1 1 0 Putative conjugal transfer nickase/helicase TraI C-term DUF370 PF04025.12 KRZ99586.1 - 0.14 12.3 0.5 0.38 10.9 0.5 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF370) Tfb2 PF03849.14 KRZ99587.1 - 3.2e-125 417.8 2.5 3.2e-125 417.8 2.5 1.5 2 0 0 2 2 2 1 Transcription factor Tfb2 Tfb2_C PF18307.1 KRZ99587.1 - 3.1e-23 82.0 0.3 6.6e-23 80.9 0.3 1.6 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 KRZ99587.1 - 3.9e-05 23.8 0.1 9.7e-05 22.5 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Ribonuc_red_lgC PF02867.15 KRZ99588.1 - 2.9e-176 587.1 0.0 4e-176 586.6 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 KRZ99588.1 - 2.9e-24 84.9 0.0 1.1e-22 79.9 0.0 3.0 3 0 0 3 3 3 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 KRZ99588.1 - 0.0011 19.5 0.1 0.0034 17.9 0.1 1.9 1 0 0 1 1 1 1 ATP cone domain Mei5 PF10376.9 KRZ99589.1 - 0.012 15.5 10.0 0.43 10.4 9.9 2.4 1 1 0 1 1 1 0 Double-strand recombination repair protein VPS28 PF03997.12 KRZ99589.1 - 0.013 15.2 2.1 0.023 14.3 2.0 1.4 1 1 0 1 1 1 0 VPS28 protein IPK PF03770.16 KRZ99589.1 - 0.042 13.7 2.0 0.055 13.3 2.0 1.1 1 0 0 1 1 1 0 Inositol polyphosphate kinase Response_reg PF00072.24 KRZ99590.1 - 9.2e-16 58.0 0.3 1.3e-15 57.5 0.3 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Cyclin PF08613.11 KRZ99591.1 - 1.7e-20 74.0 1.5 3.5e-20 73.0 1.5 1.5 1 0 0 1 1 1 1 Cyclin Orai-1 PF07856.12 KRZ99591.1 - 0.013 15.2 0.4 0.019 14.6 0.4 1.2 1 0 0 1 1 1 0 Mediator of CRAC channel activity RIBIOP_C PF04950.12 KRZ99592.1 - 1.7e-90 303.4 0.2 1.7e-90 303.4 0.2 2.3 2 0 0 2 2 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 KRZ99592.1 - 1.6e-31 108.2 0.0 1e-30 105.6 0.0 2.5 1 0 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.27 KRZ99592.1 - 1.6e-06 27.8 0.0 0.0012 18.4 0.0 3.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 KRZ99592.1 - 2.3e-05 24.9 0.7 5.1e-05 23.7 0.0 1.9 2 0 0 2 2 1 1 AAA ATPase domain AAA_33 PF13671.6 KRZ99592.1 - 3.2e-05 24.1 0.5 0.00014 22.0 0.0 2.4 2 1 0 2 2 1 1 AAA domain AAA PF00004.29 KRZ99592.1 - 3.8e-05 24.1 0.0 0.00012 22.5 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 KRZ99592.1 - 0.00016 21.7 0.2 0.0011 19.0 0.2 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 KRZ99592.1 - 0.00046 20.5 0.0 0.0015 18.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KRZ99592.1 - 0.00061 20.1 0.0 0.0021 18.4 0.0 2.0 1 0 0 1 1 1 1 RNA helicase ABC_tran PF00005.27 KRZ99592.1 - 0.0042 17.6 0.1 0.0042 17.6 0.1 2.9 3 0 0 3 3 3 1 ABC transporter NB-ARC PF00931.22 KRZ99592.1 - 0.0059 15.8 1.4 0.12 11.5 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain NACHT PF05729.12 KRZ99592.1 - 0.012 15.5 0.0 0.025 14.5 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Rad17 PF03215.15 KRZ99592.1 - 0.013 15.5 0.1 0.19 11.6 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_18 PF13238.6 KRZ99592.1 - 0.013 16.0 5.8 0.028 15.0 0.0 3.7 3 1 0 3 3 2 0 AAA domain AAA_5 PF07728.14 KRZ99592.1 - 0.018 15.0 0.1 0.047 13.7 0.1 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 KRZ99592.1 - 0.02 14.6 0.0 0.052 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KRZ99592.1 - 0.02 14.8 0.4 0.047 13.6 0.4 1.6 1 0 0 1 1 1 0 NTPase AAA_28 PF13521.6 KRZ99592.1 - 0.024 14.9 0.1 0.095 12.9 0.1 2.1 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KRZ99592.1 - 0.028 14.8 0.0 0.071 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KRZ99592.1 - 0.032 14.0 0.0 0.032 14.0 0.0 4.5 4 1 0 4 4 3 0 AAA domain AAA_7 PF12775.7 KRZ99592.1 - 0.069 12.7 0.0 0.069 12.7 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region cobW PF02492.19 KRZ99592.1 - 0.074 12.6 0.1 0.16 11.5 0.1 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Viral_helicase1 PF01443.18 KRZ99592.1 - 0.11 12.2 0.0 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.6 KRZ99592.1 - 0.14 11.7 0.0 0.36 10.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain TRP PF06011.12 KRZ99594.1 - 2.4e-151 504.3 31.1 3.4e-151 503.8 31.1 1.2 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KRZ99594.1 - 4.5e-42 143.7 1.0 8.2e-42 142.9 1.0 1.5 1 0 0 1 1 1 1 ML-like domain HemY_N PF07219.13 KRZ99594.1 - 0.12 12.6 4.4 16 5.7 0.2 3.7 3 0 0 3 3 3 0 HemY protein N-terminus Lon_C PF05362.13 KRZ99595.1 - 1.3e-45 155.5 0.0 2.3e-45 154.7 0.0 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 KRZ99595.1 - 5.9e-29 101.4 0.6 2.2e-28 99.5 0.6 2.1 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 KRZ99595.1 - 1e-23 84.2 0.0 2.5e-23 83.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KRZ99595.1 - 1.9e-08 34.4 0.0 8.4e-08 32.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KRZ99595.1 - 1.2e-06 28.7 0.0 4.1e-06 27.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) ChlI PF13541.6 KRZ99595.1 - 4.2e-06 26.6 0.1 8.9e-06 25.6 0.1 1.5 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.6 KRZ99595.1 - 5e-05 23.8 0.0 0.00015 22.2 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 KRZ99595.1 - 9.7e-05 22.2 0.0 0.00038 20.2 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KRZ99595.1 - 0.00011 22.7 0.3 0.0011 19.5 0.0 2.9 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 KRZ99595.1 - 0.00027 20.9 0.9 0.0032 17.4 0.2 2.7 1 1 1 2 2 2 1 Rad17 P-loop domain AAA_33 PF13671.6 KRZ99595.1 - 0.00028 21.1 0.0 0.00062 19.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KRZ99595.1 - 0.00033 20.9 0.1 0.011 16.0 0.1 2.7 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KRZ99595.1 - 0.00096 19.2 0.0 0.0038 17.3 0.0 2.1 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 KRZ99595.1 - 0.00097 18.4 0.0 0.0019 17.4 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain TIP49 PF06068.13 KRZ99595.1 - 0.0027 17.0 0.1 0.0053 16.0 0.1 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 KRZ99595.1 - 0.003 17.3 0.0 0.0072 16.1 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_3 PF07726.11 KRZ99595.1 - 0.003 17.4 0.0 0.0071 16.2 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KRZ99595.1 - 0.0041 17.5 0.1 0.024 15.0 0.0 2.5 2 0 0 2 2 1 1 RNA helicase Mg_chelatase PF01078.21 KRZ99595.1 - 0.0069 15.8 0.1 0.059 12.7 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI TsaE PF02367.17 KRZ99595.1 - 0.01 15.8 0.0 0.025 14.6 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 KRZ99595.1 - 0.017 14.6 0.1 0.033 13.7 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 KRZ99595.1 - 0.021 14.6 0.0 0.047 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KRZ99595.1 - 0.033 14.5 0.2 0.15 12.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KRZ99595.1 - 0.034 14.0 0.0 0.074 13.0 0.0 1.5 1 0 0 1 1 1 0 NACHT domain PhoH PF02562.16 KRZ99595.1 - 0.037 13.5 0.0 0.076 12.5 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Zeta_toxin PF06414.12 KRZ99595.1 - 0.042 13.1 0.1 0.082 12.2 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_30 PF13604.6 KRZ99595.1 - 0.051 13.3 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KRZ99595.1 - 0.053 13.4 0.2 0.29 11.0 0.1 2.2 1 1 1 2 2 2 0 NTPase ABC_tran PF00005.27 KRZ99595.1 - 0.054 14.0 1.5 0.11 13.0 0.1 2.2 2 1 0 2 2 1 0 ABC transporter AAA_28 PF13521.6 KRZ99595.1 - 0.084 13.1 0.1 0.18 12.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain DUF1907 PF08925.11 KRZ99595.1 - 0.093 12.2 0.5 0.17 11.3 0.5 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1907) DUF3298 PF11738.8 KRZ99595.1 - 0.32 12.1 3.0 18 6.4 0.5 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3298) DUF4820 PF16091.5 KRZ99595.1 - 1.2 8.5 8.4 0.15 11.4 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) Methyltransf_23 PF13489.6 KRZ99596.1 - 1.1e-13 51.3 0.0 1.9e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KRZ99596.1 - 5.3e-09 36.6 0.0 6.5e-08 33.1 0.0 2.6 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KRZ99596.1 - 1.5e-08 35.2 1.3 3.3e-08 34.2 0.2 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KRZ99596.1 - 7.6e-07 29.8 0.0 6.8e-05 23.5 0.0 2.5 1 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KRZ99596.1 - 1.3e-06 28.2 0.2 2.4e-05 24.1 0.0 2.3 1 1 1 2 2 2 1 Methyltransferase domain MNE1 PF13762.6 KRZ99597.1 - 3.1e-43 147.3 11.6 3.1e-43 147.3 11.6 3.1 2 0 0 2 2 2 1 Mitochondrial splicing apparatus component RRM_9 PF18444.1 KRZ99597.1 - 0.099 12.5 0.0 0.31 10.9 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif EF-hand_6 PF13405.6 KRZ99597.1 - 0.14 12.1 0.4 0.64 10.1 0.4 2.1 1 0 0 1 1 1 0 EF-hand domain DUF4196 PF13846.6 KRZ99598.1 - 0.019 15.1 0.4 0.019 15.1 0.4 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4196) Ribosomal_L30 PF00327.20 KRZ99599.1 - 3.9e-14 52.3 0.4 7.2e-14 51.4 0.2 1.6 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e PARG_cat PF05028.14 KRZ99600.1 - 0.021 14.1 0.0 0.053 12.8 0.0 1.6 1 0 0 1 1 1 0 Poly (ADP-ribose) glycohydrolase (PARG) Zn_clus PF00172.18 KRZ99602.1 - 8.2e-10 38.7 10.8 1.3e-09 38.0 10.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_3 PF07859.13 KRZ99603.1 - 1.7e-08 34.6 0.0 2.3e-08 34.1 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 KRZ99603.1 - 0.00022 20.9 0.1 0.0011 18.7 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KRZ99603.1 - 0.0012 17.7 1.1 0.0034 16.3 1.1 1.8 1 1 0 1 1 1 1 Steryl acetyl hydrolase LCAT PF02450.15 KRZ99603.1 - 0.0048 16.1 0.1 0.0075 15.5 0.1 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Lipase_3 PF01764.25 KRZ99603.1 - 0.032 14.1 0.0 0.071 13.0 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) LIDHydrolase PF10230.9 KRZ99603.1 - 0.039 13.5 0.0 0.048 13.2 0.0 1.3 1 1 0 1 1 1 0 Lipid-droplet associated hydrolase Hydrolase_4 PF12146.8 KRZ99603.1 - 0.064 12.5 0.0 1.1 8.4 0.0 2.6 3 0 0 3 3 3 0 Serine aminopeptidase, S33 eIF3g PF12353.8 KRZ99604.1 - 9.8e-45 152.0 6.4 1.5e-44 151.4 6.4 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 KRZ99604.1 - 1.4e-13 50.5 0.0 2.4e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KRZ99604.1 - 0.068 12.8 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_7 PF18586.1 KRZ99604.1 - 0.2 12.0 0.6 0.54 10.6 0.2 1.9 2 0 0 2 2 2 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 WD40 PF00400.32 KRZ99605.1 - 6.4e-17 61.6 11.0 1.2e-05 26.0 0.3 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KRZ99605.1 - 5.2e-07 29.9 0.2 0.46 10.8 0.0 4.7 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain STAG PF08514.11 KRZ99606.1 - 6.5e-41 138.8 0.2 4.6e-40 136.0 0.2 2.6 1 0 0 1 1 1 1 STAG domain SWIRM PF04433.17 KRZ99607.1 - 3.3e-28 97.9 0.4 1.3e-27 96.0 0.4 2.1 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.31 KRZ99607.1 - 2.8e-07 30.6 0.0 6.8e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain SWIRM-assoc_1 PF16495.5 KRZ99607.1 - 1.6e-06 28.0 6.6 3.8e-06 26.8 6.6 1.6 1 0 0 1 1 1 1 SWIRM-associated region 1 Myb_DNA-bind_6 PF13921.6 KRZ99607.1 - 0.0002 21.5 4.9 0.00031 20.9 0.5 3.5 3 1 0 3 3 3 1 Myb-like DNA-binding domain ZZ PF00569.17 KRZ99607.1 - 0.00076 19.2 2.3 0.0033 17.2 0.3 2.2 2 0 0 2 2 2 1 Zinc finger, ZZ type Chordopox_RPO7 PF05864.12 KRZ99607.1 - 0.014 15.7 1.0 0.039 14.2 0.0 2.3 2 0 0 2 2 2 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) TMPIT PF07851.13 KRZ99607.1 - 0.13 11.5 5.5 0.23 10.7 5.5 1.4 1 0 0 1 1 1 0 TMPIT-like protein zf-UBR PF02207.20 KRZ99607.1 - 0.15 12.2 0.4 0.31 11.2 0.4 1.4 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) FTR1 PF03239.14 KRZ99608.1 - 1e-94 317.2 4.1 1.3e-94 316.9 4.1 1.1 1 0 0 1 1 1 1 Iron permease FTR1 family ECF_trnsprt PF12822.7 KRZ99608.1 - 0.09 12.9 17.1 1.6 8.8 4.4 2.6 1 1 1 2 2 2 0 ECF transporter, substrate-specific component FAA_hydrolase PF01557.18 KRZ99609.1 - 9.2e-54 182.4 0.0 1.1e-53 182.1 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family dCMP_cyt_deam_1 PF00383.23 KRZ99610.1 - 3.1e-26 91.2 1.5 4.8e-26 90.6 1.5 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KRZ99610.1 - 2.1e-13 50.2 0.2 5.1e-13 49.0 0.2 1.6 1 0 0 1 1 1 1 MafB19-like deaminase AAA_18 PF13238.6 KRZ99610.1 - 0.02 15.5 0.1 0.054 14.1 0.1 1.8 1 1 0 1 1 1 0 AAA domain CoaE PF01121.20 KRZ99610.1 - 0.13 12.0 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Dephospho-CoA kinase SNAD4 PF18750.1 KRZ99610.1 - 0.13 12.4 0.3 0.29 11.3 0.3 1.6 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 NPC1_N PF16414.5 KRZ99611.1 - 8.3e-81 271.1 14.8 8.3e-81 271.1 14.8 1.7 2 0 0 2 2 2 1 Niemann-Pick C1 N terminus Patched PF02460.18 KRZ99611.1 - 2.2e-70 237.8 28.3 4.1e-70 236.9 23.8 2.7 2 1 0 2 2 2 1 Patched family Sterol-sensing PF12349.8 KRZ99611.1 - 4.9e-47 159.6 6.7 4.9e-47 159.6 6.7 2.9 3 0 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.19 KRZ99611.1 - 0.012 13.3 15.8 0.02 12.6 15.8 1.2 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family DUF4227 PF14004.6 KRZ99611.1 - 0.048 13.6 0.0 0.18 11.8 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4227) DNA_RNApol_7kD PF03604.13 KRZ99612.1 - 9.4e-16 57.2 2.7 1.2e-15 56.8 2.7 1.2 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit HypA PF01155.19 KRZ99612.1 - 0.00052 20.0 0.3 0.00052 20.0 0.3 1.1 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc-ribbon_6 PF10005.9 KRZ99612.1 - 0.0037 17.9 0.7 0.0049 17.5 0.7 1.2 1 0 0 1 1 1 1 zinc-ribbon domain C1_1 PF00130.22 KRZ99612.1 - 0.0061 16.4 0.9 0.008 16.0 0.9 1.2 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.6 KRZ99612.1 - 0.01 15.7 0.3 0.014 15.3 0.3 1.2 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Zn-ribbon_8 PF09723.10 KRZ99612.1 - 0.015 15.4 2.5 0.033 14.3 2.5 1.6 1 1 0 1 1 1 0 Zinc ribbon domain DZR PF12773.7 KRZ99612.1 - 0.016 15.2 2.0 0.043 13.8 2.0 1.7 1 1 0 1 1 1 0 Double zinc ribbon FYDLN_acid PF09538.10 KRZ99612.1 - 0.017 15.8 0.3 0.018 15.7 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) FYVE_2 PF02318.16 KRZ99612.1 - 0.025 14.8 0.5 0.028 14.6 0.5 1.1 1 0 0 1 1 1 0 FYVE-type zinc finger FYVE PF01363.21 KRZ99612.1 - 0.032 14.4 1.4 0.04 14.1 1.4 1.2 1 0 0 1 1 1 0 FYVE zinc finger UPF0547 PF10571.9 KRZ99612.1 - 0.041 14.0 0.9 1.1 9.5 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zf_UBZ PF18439.1 KRZ99612.1 - 0.069 12.8 0.9 7 6.3 0.1 2.2 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger TFIIS_C PF01096.18 KRZ99612.1 - 0.074 12.9 1.7 2.2 8.2 0.1 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zinc_ribbon_4 PF13717.6 KRZ99612.1 - 0.16 11.9 4.9 4.4 7.3 4.9 2.2 1 1 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_5 PF13719.6 KRZ99612.1 - 0.16 11.7 5.3 0.29 10.9 0.2 2.1 1 1 1 2 2 2 0 zinc-ribbon domain PPR_3 PF13812.6 KRZ99613.1 - 1.2e-05 25.2 0.3 1.2e-05 25.2 0.3 2.4 2 0 0 2 2 2 1 Pentatricopeptide repeat domain PPR_2 PF13041.6 KRZ99613.1 - 4.7e-05 23.5 2.1 6.9e-05 23.0 0.1 2.4 2 0 0 2 2 2 1 PPR repeat family WSC PF01822.19 KRZ99614.1 - 7.5e-10 38.9 13.5 7.5e-10 38.9 13.5 4.0 3 2 0 3 3 3 1 WSC domain Shisa PF13908.6 KRZ99614.1 - 0.044 14.0 0.4 0.044 14.0 0.4 3.8 1 1 2 3 3 3 0 Wnt and FGF inhibitory regulator CbtA PF09490.10 KRZ99614.1 - 0.27 11.0 0.0 0.42 10.3 0.0 1.2 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) PPI_Ypi1 PF07491.11 KRZ99615.1 - 1e-25 89.3 9.9 1e-25 89.3 9.9 2.4 2 1 0 2 2 2 1 Protein phosphatase inhibitor Atrophin-1 PF03154.15 KRZ99615.1 - 0.59 8.3 9.3 0.6 8.3 9.3 1.0 1 0 0 1 1 1 0 Atrophin-1 family CDC45 PF02724.14 KRZ99615.1 - 3.4 5.9 6.9 3.7 5.7 6.9 1.0 1 0 0 1 1 1 0 CDC45-like protein Rhomboid PF01694.22 KRZ99616.1 - 5.9e-29 101.0 12.8 5.9e-29 101.0 12.8 1.8 2 0 0 2 2 2 1 Rhomboid family DUF3671 PF12420.8 KRZ99616.1 - 0.017 15.2 2.1 0.1 12.7 0.7 2.8 2 1 0 2 2 2 0 Protein of unknown function PIRT PF15099.6 KRZ99616.1 - 0.96 9.0 3.2 6.3 6.4 1.6 2.7 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family Brix PF04427.18 KRZ99617.1 - 2.4e-41 142.0 0.3 3.2e-41 141.6 0.3 1.2 1 0 0 1 1 1 1 Brix domain ATP19 PF11022.8 KRZ99618.1 - 1.1e-23 83.3 0.0 1.3e-23 83.2 0.0 1.0 1 0 0 1 1 1 1 ATP synthase subunit K RasGAP PF00616.19 KRZ99620.1 - 1.3e-21 77.3 18.8 9.8e-17 61.3 1.9 4.7 5 1 1 6 6 6 2 GTPase-activator protein for Ras-like GTPase RNase_T PF00929.24 KRZ99621.1 - 6.8e-15 56.0 0.0 1.3e-14 55.1 0.0 1.5 1 0 0 1 1 1 1 Exonuclease DUF5051 PF16473.5 KRZ99621.1 - 0.037 14.0 0.0 0.073 13.1 0.0 1.5 1 0 0 1 1 1 0 3' exoribonuclease, RNase T-like CRIM PF16978.5 KRZ99622.1 - 1e-28 100.3 0.5 3.6e-28 98.5 0.0 2.3 2 0 0 2 2 2 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1_PH PF16979.5 KRZ99622.1 - 1.9e-15 57.0 12.4 1.1e-14 54.6 9.5 3.2 2 1 0 2 2 2 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology Pkinase PF00069.25 KRZ99623.1 - 7.4e-67 225.5 0.1 1.1e-66 224.9 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KRZ99623.1 - 1.1e-33 116.6 0.0 1.6e-33 116.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KRZ99623.1 - 9.3e-07 28.4 0.0 1.8e-05 24.2 0.0 2.3 1 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 KRZ99623.1 - 0.0013 18.2 0.1 0.0024 17.3 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KRZ99623.1 - 0.0079 15.2 0.6 0.024 13.6 0.6 1.8 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 KRZ99623.1 - 0.011 15.4 1.1 0.98 9.0 0.1 2.3 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 KRZ99623.1 - 0.075 11.8 0.0 0.075 11.8 0.0 2.2 3 0 0 3 3 3 0 Fungal protein kinase APH PF01636.23 KRZ99623.1 - 0.078 12.9 0.1 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ribosomal_L27e PF01777.18 KRZ99624.1 - 6.5e-36 122.6 7.2 8.6e-36 122.2 7.2 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 KRZ99624.1 - 0.0023 17.8 4.8 0.0064 16.4 4.8 1.8 1 1 0 1 1 1 1 KOW motif tRNA-synt_1b PF00579.25 KRZ99625.1 - 2.2e-19 69.9 0.0 7.1e-12 45.2 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (W and Y) POC3_POC4 PF10448.9 KRZ99626.1 - 6.1e-38 130.1 0.6 6.7e-38 130.0 0.6 1.0 1 0 0 1 1 1 1 20S proteasome chaperone assembly proteins 3 and 4 FNIP_C PF14638.6 KRZ99626.1 - 0.049 13.3 0.0 0.049 13.3 0.0 1.1 1 0 0 1 1 1 0 Folliculin-interacting protein C-terminus DHBP_synthase PF00926.19 KRZ99627.1 - 3.5e-86 287.6 0.1 4e-86 287.5 0.1 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase RNB PF00773.19 KRZ99628.1 - 1.4e-98 330.3 0.1 1.9e-98 329.8 0.1 1.2 1 0 0 1 1 1 1 RNB domain Rrp44_CSD1 PF17216.3 KRZ99628.1 - 5.7e-51 172.1 0.1 1.6e-50 170.7 0.1 1.8 1 0 0 1 1 1 1 Rrp44-like cold shock domain Rrp44_S1 PF17215.3 KRZ99628.1 - 4.4e-29 100.3 0.4 4.4e-29 100.3 0.4 2.1 2 0 0 2 2 2 1 S1 domain OB_Dis3 PF17849.1 KRZ99628.1 - 7.3e-19 67.6 0.0 1.7e-18 66.4 0.0 1.7 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) PIN_4 PF13638.6 KRZ99628.1 - 8.2e-17 61.7 0.8 2e-16 60.5 0.8 1.7 1 0 0 1 1 1 1 PIN domain CSD2 PF17876.1 KRZ99628.1 - 2.9e-07 30.6 0.1 0.00019 21.5 0.0 3.5 3 0 0 3 3 3 1 Cold shock domain OB_RNB PF08206.11 KRZ99628.1 - 0.089 12.5 0.0 0.38 10.5 0.0 2.0 2 0 0 2 2 2 0 Ribonuclease B OB domain TcfC PF16967.5 KRZ99628.1 - 0.1 12.1 0.3 0.39 10.2 0.0 2.2 2 0 0 2 2 2 0 E-set like domain Phage_tail_S PF05069.13 KRZ99629.1 - 0.042 13.7 0.0 0.083 12.7 0.0 1.4 1 0 0 1 1 1 0 Phage virion morphogenesis family Alph_Pro_TM PF09608.10 KRZ99629.1 - 0.063 13.1 0.1 0.14 12.0 0.1 1.5 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) RNA_pol_Rpc82 PF05645.13 KRZ99630.1 - 3.4e-73 246.6 5.1 3.4e-73 246.6 5.1 2.4 3 1 1 4 4 4 1 RNA polymerase III subunit RPC82 HTH_9 PF08221.11 KRZ99630.1 - 6.8e-23 80.5 5.2 6.5e-21 74.2 0.2 3.6 5 0 0 5 5 5 2 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.17 KRZ99630.1 - 2.4e-06 27.4 1.2 0.056 13.3 0.0 3.4 3 0 0 3 3 3 2 TFIIE alpha subunit TrmB PF01978.19 KRZ99630.1 - 7.1e-06 25.8 0.1 0.009 15.9 0.0 3.9 3 0 0 3 3 3 1 Sugar-specific transcriptional regulator TrmB Mnd1 PF03962.15 KRZ99630.1 - 9.9 6.5 8.0 9.3 6.6 0.0 4.4 5 0 0 5 5 5 0 Mnd1 HTH domain TPR_2 PF07719.17 KRZ99631.1 - 4.7e-26 88.8 41.4 0.00071 19.5 0.1 16.8 17 1 0 17 17 16 7 Tetratricopeptide repeat TPR_1 PF00515.28 KRZ99631.1 - 3e-21 74.3 44.6 0.00083 19.1 0.2 16.4 18 0 0 18 18 17 4 Tetratricopeptide repeat TPR_14 PF13428.6 KRZ99631.1 - 1.5e-18 65.8 10.0 0.17 12.8 0.0 11.7 11 2 2 13 13 11 3 Tetratricopeptide repeat TPR_19 PF14559.6 KRZ99631.1 - 5.3e-17 62.1 24.3 0.0029 18.1 0.0 11.2 9 3 3 12 12 12 6 Tetratricopeptide repeat TPR_16 PF13432.6 KRZ99631.1 - 2.4e-16 60.1 5.2 0.024 15.3 0.0 9.3 8 3 3 11 11 10 4 Tetratricopeptide repeat TPR_12 PF13424.6 KRZ99631.1 - 3.1e-15 56.2 28.0 0.22 11.8 0.1 13.0 12 4 0 12 12 11 4 Tetratricopeptide repeat TPR_8 PF13181.6 KRZ99631.1 - 4e-15 54.7 37.6 0.0012 18.9 0.1 13.3 13 1 0 13 13 11 3 Tetratricopeptide repeat TPR_22 PF18833.1 KRZ99631.1 - 3.2e-13 49.6 2.0 7.5e-13 48.4 0.0 2.8 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 KRZ99631.1 - 1.7e-11 43.6 22.5 0.0003 20.4 0.0 9.7 10 0 0 10 10 10 3 TPR repeat TPR_17 PF13431.6 KRZ99631.1 - 6.3e-11 41.9 19.4 0.021 15.2 0.0 9.8 11 0 0 11 11 8 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KRZ99631.1 - 1.2e-10 41.5 19.8 0.0004 20.6 0.0 9.0 10 1 0 10 10 8 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 KRZ99631.1 - 4.4e-08 33.2 15.5 2.4 9.0 0.0 11.1 12 1 0 12 12 9 2 Tetratricopeptide repeat TPR_9 PF13371.6 KRZ99631.1 - 1.3e-06 28.4 4.9 3.6 7.8 0.0 6.9 5 2 1 7 7 7 1 Tetratricopeptide repeat Sel1 PF08238.12 KRZ99631.1 - 8.1e-05 23.2 2.2 0.85 10.4 0.0 5.3 4 0 0 4 4 4 1 Sel1 repeat TPR_7 PF13176.6 KRZ99631.1 - 0.016 15.2 21.5 16 5.8 0.0 10.1 11 0 0 11 11 10 0 Tetratricopeptide repeat DUF3856 PF12968.7 KRZ99631.1 - 0.016 15.3 2.4 2.3 8.3 0.0 4.5 4 0 0 4 4 4 0 Domain of Unknown Function (DUF3856) RPN7 PF10602.9 KRZ99631.1 - 0.024 14.3 5.4 1.8 8.3 0.9 4.2 4 0 0 4 4 3 0 26S proteasome subunit RPN7 TPR_10 PF13374.6 KRZ99631.1 - 0.1 12.5 16.3 1.1 9.2 0.0 7.6 10 0 0 10 10 8 0 Tetratricopeptide repeat dCache_3 PF14827.6 KRZ99631.1 - 0.18 11.4 1.1 0.39 10.3 1.1 1.5 1 0 0 1 1 1 0 Double sensory domain of two-component sensor kinase Fis1_TPR_C PF14853.6 KRZ99631.1 - 0.22 11.6 7.6 15 5.7 0.0 6.2 6 0 0 6 6 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_4 PF07721.14 KRZ99631.1 - 0.32 11.8 3.0 22 6.1 0.0 4.0 4 0 0 4 4 2 0 Tetratricopeptide repeat ATG13 PF10033.9 KRZ99632.1 - 2.6e-76 256.5 0.2 5.4e-76 255.4 0.2 1.6 1 0 0 1 1 1 1 Autophagy-related protein 13 AFG1_ATPase PF03969.16 KRZ99633.1 - 1.2e-70 238.3 0.0 3.6e-67 226.8 0.0 2.3 2 1 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.6 KRZ99633.1 - 0.00013 22.4 0.3 0.019 15.4 0.3 2.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 KRZ99633.1 - 0.013 15.5 0.0 0.036 14.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 KRZ99633.1 - 0.017 14.5 0.0 0.036 13.5 0.0 1.6 1 0 0 1 1 1 0 Bacterial TniB protein AAA_5 PF07728.14 KRZ99633.1 - 0.033 14.2 0.0 0.067 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KRZ99633.1 - 0.055 13.7 0.4 0.23 11.7 0.4 2.0 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 KRZ99633.1 - 0.068 13.1 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA PF00004.29 KRZ99633.1 - 0.1 13.0 0.0 0.33 11.4 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 KRZ99633.1 - 0.14 12.1 0.7 0.26 11.2 0.0 1.8 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea SBE2 PF17076.5 KRZ99634.1 - 0.42 8.8 75.0 0.0025 16.2 61.0 2.6 1 1 0 2 2 2 0 SBE2, cell-wall formation Suf PF05843.14 KRZ99635.1 - 5.2e-08 33.2 27.3 0.027 14.5 0.4 5.9 4 2 0 5 5 5 4 Suppressor of forked protein (Suf) NRDE-2 PF08424.10 KRZ99635.1 - 2.1e-06 27.1 17.1 4e-05 22.9 1.2 5.2 3 1 1 5 5 5 2 NRDE-2, necessary for RNA interference Mad3_BUB1_I PF08311.12 KRZ99635.1 - 0.00018 21.5 19.8 2.9 7.9 0.1 8.0 5 3 2 8 8 8 3 Mad3/BUB1 homology region 1 TPR_14 PF13428.6 KRZ99635.1 - 0.036 14.9 0.0 2.6e+02 2.9 0.0 5.6 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_15 PF13429.6 KRZ99635.1 - 0.096 11.9 0.0 2 7.5 0.0 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 KRZ99635.1 - 0.56 10.7 3.7 1.7 9.2 0.4 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat FRB_dom PF08771.11 KRZ99635.1 - 0.95 9.9 5.8 5.3 7.5 0.2 4.2 4 0 0 4 4 4 0 FKBP12-rapamycin binding domain ATP-synt_D PF01813.17 KRZ99636.1 - 6e-71 238.3 4.6 6e-71 238.3 4.6 1.3 2 0 0 2 2 2 1 ATP synthase subunit D Ribosomal_L6e PF01159.19 KRZ99636.1 - 0.011 16.2 3.6 0.011 16.2 3.6 2.1 2 1 0 2 2 2 0 Ribosomal protein L6e PHM7_cyt PF14703.6 KRZ99636.1 - 0.034 14.4 4.7 0.11 12.7 0.7 2.3 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter adh_short_C2 PF13561.6 KRZ99637.1 - 1.3e-62 211.4 0.0 1.6e-62 211.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KRZ99637.1 - 4.5e-41 140.5 0.1 5.3e-41 140.2 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KRZ99637.1 - 5.3e-10 39.5 0.1 7.7e-10 39.0 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KRZ99637.1 - 7e-05 22.4 0.1 0.00013 21.5 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KRZ99637.1 - 0.0027 16.9 0.1 0.22 10.6 0.0 2.5 3 0 0 3 3 3 1 RmlD substrate binding domain Sacchrp_dh_NADP PF03435.18 KRZ99637.1 - 0.0055 17.0 0.0 0.0086 16.3 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain DFP PF04127.15 KRZ99637.1 - 0.024 14.5 0.1 0.041 13.7 0.1 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein GDP_Man_Dehyd PF16363.5 KRZ99637.1 - 0.026 13.9 0.0 0.098 12.0 0.0 1.7 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase 2-Hacid_dh_C PF02826.19 KRZ99637.1 - 0.17 11.2 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 KRZ99638.1 - 2.5e-126 422.2 0.9 3.4e-126 421.7 0.9 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 KRZ99638.1 - 1.7e-45 154.1 0.7 2.6e-45 153.5 0.7 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Thi4 PF01946.17 KRZ99638.1 - 1e-05 24.9 0.1 0.015 14.5 0.0 2.4 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.22 KRZ99638.1 - 2.4e-05 23.6 2.0 0.0079 15.3 0.3 2.8 3 0 0 3 3 3 2 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 KRZ99638.1 - 0.00023 20.5 0.9 0.0017 17.6 0.3 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KRZ99638.1 - 0.0028 17.0 0.1 0.0066 15.7 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KRZ99638.1 - 0.009 15.6 0.9 0.06 12.9 0.9 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KRZ99638.1 - 0.034 14.4 0.1 0.12 12.6 0.1 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KRZ99638.1 - 0.11 11.1 0.3 0.7 8.5 0.0 2.4 3 0 0 3 3 3 0 HI0933-like protein Pyr_redox_3 PF13738.6 KRZ99638.1 - 0.12 11.7 0.5 1.8 7.8 0.0 2.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KRZ99638.1 - 0.16 12.4 0.0 0.4 11.1 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding AATase PF07247.12 KRZ99639.1 - 2.4e-14 52.8 0.0 2.5e-14 52.7 0.0 1.0 1 0 0 1 1 1 1 Alcohol acetyltransferase AATase PF07247.12 KRZ99640.1 - 5.4e-43 147.3 3.7 7e-43 146.9 3.7 1.1 1 0 0 1 1 1 1 Alcohol acetyltransferase adh_short_C2 PF13561.6 KRZ99641.1 - 6.6e-57 192.8 0.1 8.2e-57 192.4 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KRZ99641.1 - 1e-40 139.3 0.2 1.2e-40 139.1 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KRZ99641.1 - 1.2e-12 48.1 0.4 1.7e-12 47.6 0.4 1.1 1 0 0 1 1 1 1 KR domain EcoRI PF02963.16 KRZ99641.1 - 0.0004 19.5 0.1 0.00053 19.1 0.1 1.1 1 0 0 1 1 1 1 Restriction endonuclease EcoRI 3Beta_HSD PF01073.19 KRZ99641.1 - 0.0018 17.3 0.1 0.0024 16.9 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KRZ99641.1 - 0.003 16.8 0.1 0.0041 16.3 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DUF4347 PF14252.6 KRZ99641.1 - 0.066 13.1 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4347) CBFD_NFYB_HMF PF00808.23 KRZ99642.1 - 3.5e-14 52.8 0.7 4.9e-14 52.4 0.7 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KRZ99642.1 - 0.00013 22.3 0.1 0.00019 21.8 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 FGGY_C PF02782.16 KRZ99643.1 - 1.9e-56 190.9 0.3 3.1e-56 190.2 0.3 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KRZ99643.1 - 4.9e-22 78.7 0.0 1.4e-21 77.2 0.0 1.8 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Hexokinase_1 PF00349.21 KRZ99643.1 - 0.1 12.5 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 Hexokinase Sulfate_transp PF00916.20 KRZ99644.1 - 3.7e-114 381.4 16.5 4.8e-114 381.1 16.5 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KRZ99644.1 - 3.4e-06 26.7 0.0 7.4e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 KRZ99644.1 - 0.0012 19.3 1.8 0.0012 19.3 1.8 2.4 2 0 0 2 2 2 1 Molybdate transporter of MFS superfamily CPBP PF02517.16 KRZ99644.1 - 0.016 15.6 1.3 0.032 14.6 0.0 2.2 2 1 0 2 2 2 0 CPBP intramembrane metalloprotease YdjM PF04307.14 KRZ99644.1 - 0.7 9.2 3.6 1.8 7.8 3.6 1.7 1 0 0 1 1 1 0 LexA-binding, inner membrane-associated putative hydrolase CAF1A PF12253.8 KRZ99645.1 - 1.9e-24 85.6 10.2 1.9e-24 85.6 10.2 4.8 3 1 2 5 5 5 1 Chromatin assembly factor 1 subunit A DUF5401 PF17380.2 KRZ99645.1 - 0.0056 14.8 55.5 0.01 14.0 55.5 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5401) Slx4 PF09494.10 KRZ99646.1 - 3.5e-10 39.7 0.1 9e-10 38.4 0.1 1.7 1 0 0 1 1 1 1 Slx4 endonuclease T_cell_tran_alt PF15128.6 KRZ99647.1 - 0.65 9.8 3.2 0.97 9.3 3.2 1.4 1 1 0 1 1 1 0 T-cell leukemia translocation-altered JmjC PF02373.22 KRZ99648.1 - 6.6e-38 129.6 4.6 8.9e-37 126.0 0.4 2.9 2 0 0 2 2 2 1 JmjC domain, hydroxylase JmjN PF02375.17 KRZ99648.1 - 4.8e-13 48.8 1.2 4.8e-13 48.8 1.2 2.2 2 0 0 2 2 2 1 jmjN domain zf-HC5HC2H PF13771.6 KRZ99648.1 - 4.2e-12 46.2 5.1 4.2e-12 46.2 5.1 2.2 2 0 0 2 2 2 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 KRZ99648.1 - 4.7e-09 36.4 3.4 4.7e-09 36.4 3.4 2.0 2 0 0 2 2 2 1 PHD-zinc-finger like domain Flag1_repress PF03614.13 KRZ99648.1 - 0.023 14.5 0.0 0.074 12.9 0.0 1.8 1 0 0 1 1 1 0 Repressor of phase-1 flagellin Rad17 PF03215.15 KRZ99649.1 - 1.3e-32 113.2 0.1 3.5e-32 111.8 0.1 1.7 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 KRZ99649.1 - 0.0014 19.0 0.0 0.0063 16.9 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 KRZ99649.1 - 0.0023 18.3 0.0 0.008 16.6 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KRZ99649.1 - 0.0059 17.0 0.0 0.022 15.2 0.0 2.0 1 0 0 1 1 1 1 RNA helicase T2SSE PF00437.20 KRZ99649.1 - 0.0077 15.3 0.0 0.022 13.8 0.0 1.7 1 0 0 1 1 1 1 Type II/IV secretion system protein FAS_N PF17828.1 KRZ99649.1 - 0.038 14.0 1.4 0.081 12.9 0.0 2.3 2 0 0 2 2 2 0 N-terminal domain in fatty acid synthase subunit beta ABC_tran PF00005.27 KRZ99649.1 - 0.047 14.2 2.2 0.089 13.3 0.0 2.5 2 1 0 2 2 2 0 ABC transporter AAA_5 PF07728.14 KRZ99649.1 - 0.084 12.9 0.0 0.21 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RsgA_GTPase PF03193.16 KRZ99649.1 - 0.097 12.6 0.0 0.3 11.0 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase Glutaredoxin PF00462.24 KRZ99650.1 - 1.3e-19 70.2 0.0 4.7e-18 65.2 0.0 2.5 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.20 KRZ99650.1 - 1.7e-14 53.6 0.0 4.4e-14 52.3 0.0 1.6 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.6 KRZ99650.1 - 0.00037 20.8 0.0 0.028 14.7 0.0 2.6 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 KRZ99650.1 - 0.0047 17.4 0.0 0.066 13.7 0.0 2.6 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 KRZ99650.1 - 0.0067 16.2 0.0 0.018 14.8 0.0 1.6 2 0 0 2 2 2 1 Thioredoxin Ribosomal_60s PF00428.19 KRZ99650.1 - 0.011 16.3 1.6 0.024 15.2 1.6 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein OST3_OST6 PF04756.13 KRZ99650.1 - 0.052 12.9 0.0 0.056 12.8 0.0 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family zf-C2H2 PF00096.26 KRZ99651.1 - 6.7e-08 32.6 13.7 0.0002 21.6 1.5 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KRZ99651.1 - 6.5e-06 26.3 7.6 2e-05 24.8 3.9 2.8 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KRZ99651.1 - 1.5e-05 25.4 12.4 0.0075 17.0 1.4 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.7 KRZ99651.1 - 0.0012 19.2 0.9 1.1 9.7 0.0 3.1 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KRZ99651.1 - 0.044 14.1 1.4 6.3 7.2 0.1 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding DUF350 PF03994.14 KRZ99652.1 - 0.056 13.6 2.8 0.22 11.7 0.1 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF350) Mem_trans PF03547.18 KRZ99652.1 - 0.68 8.3 4.7 0.87 7.9 4.7 1.0 1 0 0 1 1 1 0 Membrane transport protein DUF4149 PF13664.6 KRZ99653.1 - 2e-22 79.4 2.2 7.9e-22 77.5 1.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) MutS_V PF00488.21 KRZ99654.1 - 1.2e-62 211.3 0.1 2.1e-62 210.5 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KRZ99654.1 - 4.5e-19 69.4 0.9 7.6e-19 68.7 0.1 1.7 2 1 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 KRZ99654.1 - 2.6e-11 43.7 0.4 7.2e-11 42.3 0.4 1.8 1 0 0 1 1 1 1 MutS family domain IV AAA_27 PF13514.6 KRZ99654.1 - 0.028 14.0 0.0 0.071 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KRZ99654.1 - 0.029 14.1 0.3 0.073 12.8 0.1 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_23 PF13476.6 KRZ99654.1 - 6 7.3 9.0 0.2 12.1 0.4 2.6 3 0 0 3 3 3 0 AAA domain MutS_I PF01624.20 KRZ99655.1 - 1.3e-32 112.4 0.0 2.2e-32 111.6 0.0 1.4 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 KRZ99655.1 - 1.5e-14 54.4 1.2 2.6e-14 53.7 0.1 1.9 2 0 0 2 2 2 1 MutS domain II LRR_9 PF14580.6 KRZ99655.1 - 0.11 12.0 0.6 0.21 11.0 0.6 1.4 1 0 0 1 1 1 0 Leucine-rich repeat NOA36 PF06524.12 KRZ99655.1 - 8.5 5.6 14.4 22 4.3 14.4 1.7 1 0 0 1 1 1 0 NOA36 protein NTP_transferase PF00483.23 KRZ99656.1 - 4.7e-23 82.1 0.0 5.9e-14 52.3 0.0 2.6 2 1 1 3 3 3 2 Nucleotidyl transferase Hexapep PF00132.24 KRZ99656.1 - 8.8e-11 41.1 16.5 5.9e-07 29.0 1.5 3.8 2 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 KRZ99656.1 - 1.3e-07 30.9 3.1 3e-07 29.7 3.1 1.5 1 1 0 1 1 1 1 L-fucokinase Hexapep_2 PF14602.6 KRZ99656.1 - 0.00017 21.3 12.2 0.012 15.4 0.7 3.1 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase NTP_transf_3 PF12804.7 KRZ99656.1 - 0.0002 21.8 0.0 0.00031 21.1 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain CHORD PF04968.12 KRZ99657.1 - 0.001 19.8 2.7 0.0023 18.6 2.7 1.6 1 0 0 1 1 1 1 CHORD EMC1_C PF07774.13 KRZ99657.1 - 0.1 12.3 0.9 0.25 11.0 0.0 2.0 3 0 0 3 3 3 0 ER membrane protein complex subunit 1, C-terminal KIX_2 PF16987.5 KRZ99657.1 - 0.21 11.6 2.1 1.3 9.1 0.2 2.9 3 1 0 3 3 3 0 KIX domain DASH_Ask1 PF08655.10 KRZ99658.1 - 0.016 15.1 0.2 0.76 9.7 0.2 2.3 1 1 1 2 2 2 0 DASH complex subunit Ask1 Fungal_trans_2 PF11951.8 KRZ99660.1 - 6.4e-80 268.8 6.6 7.4e-80 268.6 6.6 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain RTX_C PF08339.10 KRZ99660.1 - 0.059 13.4 0.6 0.21 11.6 0.1 2.0 2 0 0 2 2 2 0 RTX C-terminal domain Acetyltransf_1 PF00583.25 KRZ99663.1 - 2.5e-05 24.5 0.0 5.4e-05 23.4 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 KRZ99663.1 - 0.007 17.0 0.0 0.013 16.1 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KRZ99663.1 - 0.013 15.9 0.0 0.037 14.4 0.0 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Fungal_trans PF04082.18 KRZ99664.1 - 1.8e-13 50.2 0.5 1.8e-13 50.2 0.5 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Acetyltransf_1 PF00583.25 KRZ99665.1 - 2.8e-13 50.1 0.0 3.7e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KRZ99665.1 - 4.7e-07 30.1 0.0 6.5e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KRZ99665.1 - 3.5e-05 23.7 0.0 4.4e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KRZ99665.1 - 0.00068 20.3 0.0 0.00084 20.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KRZ99665.1 - 0.0083 16.2 0.0 0.016 15.3 0.0 1.6 1 1 0 1 1 1 1 GCN5-related N-acetyl-transferase RRM_1 PF00076.22 KRZ99665.1 - 0.025 14.4 0.0 0.043 13.6 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PanZ PF12568.8 KRZ99665.1 - 0.037 13.8 0.0 0.045 13.5 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ zf-C2H2 PF00096.26 KRZ99666.1 - 5e-12 45.6 13.4 3.1e-06 27.3 1.8 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KRZ99666.1 - 1.2e-08 35.0 13.0 0.00047 20.8 1.9 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KRZ99666.1 - 8.4e-08 32.3 8.0 0.00067 19.9 0.1 2.8 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 KRZ99666.1 - 6.6e-07 29.5 19.7 4.8e-05 23.6 5.8 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-BED PF02892.15 KRZ99666.1 - 8e-06 25.8 4.0 0.016 15.2 1.9 2.6 2 0 0 2 2 2 2 BED zinc finger zf-C2H2_2 PF12756.7 KRZ99666.1 - 0.0024 18.2 4.9 0.14 12.5 1.2 2.7 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.12 KRZ99666.1 - 0.0089 16.3 5.9 0.022 15.1 6.0 1.6 1 1 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 KRZ99666.1 - 0.012 15.6 4.6 0.012 15.6 4.6 2.5 2 1 0 2 2 2 0 C2H2-type zinc finger zf-C2HE PF16278.5 KRZ99666.1 - 0.014 15.8 10.3 0.92 10.0 2.9 2.8 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-met PF12874.7 KRZ99666.1 - 0.016 15.6 7.6 1.4 9.4 2.6 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-AN1 PF01428.16 KRZ99666.1 - 0.089 13.0 3.0 1.7 8.9 0.3 2.3 2 0 0 2 2 2 0 AN1-like Zinc finger zf-C2H2_9 PF16293.5 KRZ99666.1 - 0.097 12.5 1.1 18 5.3 0.2 2.7 1 1 1 2 2 2 0 C2H2 type zinc-finger (1 copy) PyrI_C PF02748.15 KRZ99666.1 - 0.12 12.3 3.2 0.33 10.9 3.0 1.9 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain FOXP-CC PF16159.5 KRZ99666.1 - 0.23 12.1 2.5 5.1 7.8 0.3 2.4 2 0 0 2 2 2 0 FOXP coiled-coil domain zf-C2H2_3rep PF18868.1 KRZ99666.1 - 0.95 10.1 4.6 6.6 7.4 3.0 2.6 1 1 0 1 1 1 0 Zinc finger C2H2-type, 3 repeats zf_C2H2_ZHX PF18387.1 KRZ99666.1 - 1.4 8.6 5.8 7.2 6.3 0.2 2.7 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain DUF629 PF04780.12 KRZ99666.1 - 1.6 7.2 6.5 5.2 5.5 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF629) ADH_zinc_N PF00107.26 KRZ99667.1 - 6.7e-11 42.3 0.4 1.3e-10 41.4 0.4 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KRZ99667.1 - 2.5e-06 27.3 2.0 0.00022 21.1 0.8 3.0 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KRZ99667.1 - 0.11 13.6 0.1 0.28 12.2 0.1 1.8 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Abhydrolase_1 PF00561.20 KRZ99668.1 - 4.7e-27 95.3 0.0 5.1e-26 91.9 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KRZ99668.1 - 1.6e-26 93.1 0.0 2.3e-26 92.6 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KRZ99668.1 - 4.5e-18 66.7 0.0 5.8e-18 66.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KRZ99668.1 - 3.8e-06 26.5 0.0 0.076 12.5 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_4 PF08386.10 KRZ99668.1 - 8.7e-05 22.6 0.0 0.0011 19.0 0.0 2.5 4 0 0 4 4 3 1 TAP-like protein Abhydrolase_5 PF12695.7 KRZ99668.1 - 9.2e-05 22.3 0.0 0.066 13.0 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family DUF1749 PF08538.10 KRZ99668.1 - 0.00057 19.1 0.1 0.023 13.8 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1749) Ndr PF03096.14 KRZ99668.1 - 0.00067 18.4 0.0 0.0013 17.5 0.0 1.4 1 0 0 1 1 1 1 Ndr family DUF915 PF06028.11 KRZ99668.1 - 0.00083 18.8 0.0 0.042 13.2 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) DLH PF01738.18 KRZ99668.1 - 0.0043 16.6 0.1 0.019 14.5 0.0 1.9 2 1 0 2 2 2 1 Dienelactone hydrolase family Ser_hydrolase PF06821.13 KRZ99668.1 - 0.026 14.4 0.0 0.56 10.0 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase FSH1 PF03959.13 KRZ99668.1 - 0.045 13.4 0.0 0.074 12.7 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 KRZ99668.1 - 0.065 13.0 0.0 0.27 11.0 0.0 1.8 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Acyl_transf_2 PF02273.15 KRZ99668.1 - 0.18 11.0 0.1 0.54 9.4 0.0 1.7 2 0 0 2 2 2 0 Acyl transferase Epimerase PF01370.21 KRZ99669.1 - 3.9e-11 42.9 0.0 6.4e-11 42.2 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KRZ99669.1 - 2.2e-10 40.2 0.0 2.9e-10 39.8 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 KRZ99669.1 - 4.8e-10 38.9 0.0 6.2e-10 38.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KRZ99669.1 - 0.00017 21.6 0.0 0.00025 21.0 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Eisosome1 PF12757.7 KRZ99670.1 - 1.3e-22 80.3 6.9 1.3e-22 80.3 6.9 6.1 3 2 1 5 5 5 1 Eisosome protein 1 Histone PF00125.24 KRZ99672.1 - 3.4e-42 143.9 0.9 3.4e-42 143.9 0.9 1.6 1 1 1 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KRZ99672.1 - 0.00031 21.1 0.0 0.00062 20.1 0.0 1.5 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KRZ99672.1 - 0.00078 19.5 0.0 0.0015 18.6 0.0 1.6 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 KRZ99672.1 - 0.011 15.9 0.2 0.023 15.0 0.2 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KRZ99672.1 - 0.044 13.9 0.0 0.072 13.2 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit PIRT PF15099.6 KRZ99673.1 - 0.094 12.3 0.5 0.2 11.2 0.5 1.5 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family Actin PF00022.19 KRZ99674.1 - 3.9e-17 62.0 0.0 2.4e-16 59.4 0.0 1.9 1 1 0 1 1 1 1 Actin RasGAP PF00616.19 KRZ99674.1 - 0.22 11.2 2.2 0.14 11.9 0.3 1.6 2 0 0 2 2 2 0 GTPase-activator protein for Ras-like GTPase DNA_ligase_A_M PF01068.21 KRZ99675.1 - 1.5e-64 217.4 0.1 2.5e-64 216.7 0.1 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KRZ99675.1 - 1.7e-45 155.4 0.3 4.2e-45 154.2 0.3 1.7 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 KRZ99675.1 - 1.6e-24 86.3 0.0 4.3e-24 85.0 0.0 1.8 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 KRZ99675.1 - 3.6e-05 24.2 0.0 6.2e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 RNA ligase DNA_ligase_OB_2 PF14743.6 KRZ99675.1 - 0.0029 17.6 0.6 1.3 9.1 0.1 2.8 2 0 0 2 2 2 2 DNA ligase OB-like domain Per1 PF04080.13 KRZ99676.1 - 3.4e-82 276.0 17.9 4.6e-82 275.6 17.9 1.1 1 0 0 1 1 1 1 Per1-like family Noc2 PF03715.13 KRZ99676.1 - 0.016 14.5 1.3 0.02 14.2 0.2 1.7 2 0 0 2 2 2 0 Noc2p family Ceramidase PF05875.12 KRZ99676.1 - 0.033 13.6 16.2 0.23 10.8 1.3 2.2 2 0 0 2 2 2 0 Ceramidase PH_11 PF15413.6 KRZ99678.1 - 9.2e-17 61.4 3.1 1.4e-16 60.9 0.4 2.7 2 0 0 2 2 2 1 Pleckstrin homology domain MMM1 PF10296.9 KRZ99678.1 - 0.00051 19.2 0.0 0.00051 19.2 0.0 3.3 3 1 1 4 4 4 1 Maintenance of mitochondrial morphology protein 1 PH PF00169.29 KRZ99678.1 - 0.00062 20.2 0.6 0.004 17.6 0.6 2.5 1 1 0 1 1 1 1 PH domain PI3_PI4_kinase PF00454.27 KRZ99679.1 - 4.6e-54 183.9 0.5 3.7e-53 180.9 0.2 2.7 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase UME PF08064.13 KRZ99679.1 - 2.9e-23 81.7 1.2 3.6e-22 78.2 0.3 3.3 2 0 0 2 2 2 1 UME (NUC010) domain FATC PF02260.20 KRZ99679.1 - 8.3e-10 38.3 0.0 2.1e-09 37.1 0.0 1.7 1 0 0 1 1 1 1 FATC domain DUF3884 PF13024.6 KRZ99679.1 - 0.036 13.6 0.0 0.21 11.2 0.0 2.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3884) UPF0257 PF06788.13 KRZ99679.1 - 0.037 13.9 0.3 0.078 12.8 0.3 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0257) TPR_20 PF14561.6 KRZ99679.1 - 0.046 14.1 0.3 0.22 11.9 0.2 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 KRZ99679.1 - 0.046 14.2 0.1 0.15 12.6 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF4976 PF16347.5 KRZ99679.1 - 0.065 13.5 0.8 7.5 6.9 0.0 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4976) CKS PF01111.19 KRZ99680.1 - 3.6e-34 116.9 0.2 5.2e-34 116.3 0.2 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit PRMT5 PF05185.16 KRZ99681.1 - 1.4e-45 155.3 0.5 2.6e-45 154.4 0.2 1.5 1 1 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 KRZ99681.1 - 4.4e-34 117.9 1.8 7.4e-34 117.1 1.8 1.3 1 0 0 1 1 1 1 PRMT5 oligomerisation domain PRMT5_TIM PF17285.2 KRZ99681.1 - 6.2e-09 35.4 0.2 9.7e-09 34.8 0.2 1.3 1 0 0 1 1 1 1 PRMT5 TIM barrel domain RrnaAD PF00398.20 KRZ99681.1 - 0.041 12.9 0.0 0.073 12.1 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_28 PF02636.17 KRZ99681.1 - 0.11 12.2 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase CWC25 PF12542.8 KRZ99682.1 - 4.4e-14 53.2 3.7 4.4e-14 53.2 3.7 3.5 2 1 1 3 3 3 1 Pre-mRNA splicing factor Cir_N PF10197.9 KRZ99682.1 - 5.8e-11 42.4 13.1 1.8e-10 40.8 13.1 1.9 1 0 0 1 1 1 1 N-terminal domain of CBF1 interacting co-repressor CIR SUI1 PF01253.22 KRZ99683.1 - 7.9e-29 100.0 0.4 1.3e-28 99.4 0.4 1.3 1 0 0 1 1 1 1 Translation initiation factor SUI1 Peptidase_C1_2 PF03051.15 KRZ99684.1 - 9e-161 535.5 2.2 1e-160 535.3 2.2 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.23 KRZ99684.1 - 1.9e-06 28.1 0.1 0.0027 17.8 0.1 2.4 2 0 0 2 2 2 2 Papain family cysteine protease CTP_transf_1 PF01148.20 KRZ99685.1 - 1.4e-78 264.4 19.0 1.8e-78 264.0 19.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family DUF4711 PF15829.5 KRZ99685.1 - 0.19 11.6 1.7 0.36 10.7 1.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4711) RR_TM4-6 PF06459.12 KRZ99685.1 - 1.5 8.6 4.0 1.6 8.5 0.4 2.0 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Macoilin PF09726.9 KRZ99686.1 - 0.057 12.0 10.9 0.064 11.8 10.9 1.1 1 0 0 1 1 1 0 Macoilin family SPX PF03105.19 KRZ99686.1 - 0.37 10.7 17.3 0.54 10.1 17.3 1.3 1 0 0 1 1 1 0 SPX domain SOG2 PF10428.9 KRZ99686.1 - 2.5 7.2 26.6 4.2 6.5 26.6 1.4 1 0 0 1 1 1 0 RAM signalling pathway protein MIOX PF05153.15 KRZ99687.1 - 2.5e-120 400.7 4.8 3.1e-120 400.4 4.8 1.1 1 0 0 1 1 1 1 Myo-inositol oxygenase HD PF01966.22 KRZ99687.1 - 0.027 14.7 0.0 0.63 10.3 0.0 2.5 2 0 0 2 2 2 0 HD domain HD_6 PF18019.1 KRZ99687.1 - 0.16 12.0 0.3 0.26 11.4 0.0 1.7 2 0 0 2 2 2 0 HD domain SSF PF00474.17 KRZ99688.1 - 7.8e-05 21.7 27.2 0.0011 18.0 27.1 2.1 1 1 0 1 1 1 1 Sodium:solute symporter family TMEM126 PF07114.11 KRZ99688.1 - 0.044 13.2 0.6 0.084 12.3 0.6 1.4 1 0 0 1 1 1 0 Transmembrane protein 126 DUF4558 PF15104.6 KRZ99689.1 - 0.065 13.3 0.8 0.37 10.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4558) NAD_binding_2 PF03446.15 KRZ99690.1 - 3.3e-41 141.1 0.0 4.7e-41 140.6 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KRZ99690.1 - 2.1e-18 66.7 0.0 3.8e-18 65.9 0.0 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase GFO_IDH_MocA PF01408.22 KRZ99690.1 - 0.017 15.9 0.0 0.062 14.1 0.0 1.8 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold DUF1160 PF06648.11 KRZ99690.1 - 0.024 14.6 0.3 0.047 13.7 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1160) F420_oxidored PF03807.17 KRZ99690.1 - 0.052 14.1 0.0 0.11 13.1 0.0 1.7 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DASH_Dad2 PF08654.10 KRZ99690.1 - 0.077 13.4 0.0 0.14 12.6 0.0 1.4 1 0 0 1 1 1 0 DASH complex subunit Dad2 Nab2 PF11517.8 KRZ99690.1 - 0.12 12.7 0.1 0.28 11.5 0.1 1.6 1 0 0 1 1 1 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) DUF1989 PF09347.10 KRZ99691.1 - 7.1e-57 191.7 0.0 8.9e-57 191.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) DUF2634 PF10934.8 KRZ99692.1 - 0.00012 22.2 1.0 0.00045 20.3 0.6 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF2634) BPL_LplA_LipB PF03099.19 KRZ99692.1 - 0.00019 21.4 0.0 0.00051 20.0 0.0 1.7 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family UPF0086 PF01868.16 KRZ99693.1 - 5.7e-22 77.4 0.1 1.5e-21 76.1 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function UPF0086 Vps51 PF08700.11 KRZ99694.1 - 7.3e-07 29.2 3.3 9e-07 28.9 1.0 2.4 2 0 0 2 2 2 1 Vps51/Vps67 DUF3641 PF12345.8 KRZ99694.1 - 0.12 12.4 1.0 0.31 11.1 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3641) TAN PF11640.8 KRZ99694.1 - 0.13 12.4 7.8 0.35 11.0 0.1 2.7 3 0 0 3 3 3 0 Telomere-length maintenance and DNA damage repair Toprim_3 PF13362.6 KRZ99694.1 - 0.15 12.4 0.1 0.54 10.7 0.0 1.9 1 1 1 2 2 2 0 Toprim domain RNA_pol_Rpc34 PF05158.12 KRZ99695.1 - 1.5e-93 313.9 0.7 1.7e-93 313.7 0.7 1.0 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit NES_C_h PF18208.1 KRZ99695.1 - 0.014 15.7 1.2 0.034 14.4 0.6 2.0 2 0 0 2 2 2 0 Nicking enzyme C-terminal middle helical domain Rrf2 PF02082.20 KRZ99695.1 - 0.061 13.7 0.7 0.11 12.9 0.1 1.7 2 0 0 2 2 2 0 Transcriptional regulator RPA_C PF08784.11 KRZ99695.1 - 0.089 13.5 0.1 0.22 12.2 0.1 1.7 1 0 0 1 1 1 0 Replication protein A C terminal DUF5415 PF17436.2 KRZ99696.1 - 0.023 14.8 0.2 0.17 12.0 0.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5415) OTCace PF00185.24 KRZ99697.1 - 2.2e-47 161.1 0.1 4e-47 160.2 0.0 1.4 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 KRZ99697.1 - 5.8e-41 140.0 0.1 8.9e-41 139.4 0.1 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain Epimerase PF01370.21 KRZ99698.1 - 3.2e-17 62.8 0.0 5.7e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KRZ99698.1 - 7.6e-15 54.6 0.0 1e-14 54.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KRZ99698.1 - 2.1e-10 40.8 0.0 3.9e-10 39.9 0.0 1.4 2 0 0 2 2 2 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KRZ99698.1 - 1.2e-09 37.7 0.6 1e-07 31.4 0.6 2.1 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 KRZ99698.1 - 1.2e-06 28.1 0.2 3.8e-06 26.5 0.2 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KRZ99698.1 - 3.2e-06 26.9 0.5 9.8e-06 25.3 0.2 1.9 2 0 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.15 KRZ99698.1 - 5.5e-05 22.4 0.6 8.8e-05 21.8 0.6 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 KRZ99698.1 - 0.00062 19.3 0.1 0.0012 18.3 0.1 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KRZ99698.1 - 0.0018 17.9 0.0 0.0039 16.8 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DapB_N PF01113.20 KRZ99698.1 - 0.0031 17.6 0.2 0.0069 16.5 0.1 1.8 2 1 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus Zeta_toxin PF06414.12 KRZ99698.1 - 0.011 15.0 0.2 0.017 14.4 0.2 1.3 1 0 0 1 1 1 0 Zeta toxin Semialdhyde_dh PF01118.24 KRZ99698.1 - 0.022 15.2 0.2 0.1 13.1 0.1 2.1 1 1 1 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain DUF3381 PF11861.8 KRZ99698.1 - 0.11 12.3 0.0 0.3 10.9 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) DUF3589 PF12141.8 KRZ99699.1 - 1.7e-195 650.3 5.2 2e-195 650.1 5.2 1.0 1 0 0 1 1 1 1 Beta-mannosyltransferases P63C PF10546.9 KRZ99699.1 - 0.016 15.8 0.9 8 7.1 0.1 2.8 2 0 0 2 2 2 0 P63C domain WD40 PF00400.32 KRZ99700.1 - 6.1e-17 61.7 18.2 1.4e-05 25.8 0.1 10.3 10 0 0 10 10 10 4 WD domain, G-beta repeat CPSF_A PF03178.15 KRZ99700.1 - 0.0031 16.9 0.1 0.051 12.9 0.1 3.0 1 1 1 2 2 2 1 CPSF A subunit region Kelch_2 PF07646.15 KRZ99700.1 - 0.0079 16.1 1.0 6.2 7.0 0.1 5.2 5 0 0 5 5 5 1 Kelch motif ANAPC4_WD40 PF12894.7 KRZ99700.1 - 0.048 14.0 1.5 1 9.7 0.0 4.1 6 0 0 6 6 6 0 Anaphase-promoting complex subunit 4 WD40 domain tRNA-synt_1 PF00133.22 KRZ99701.1 - 2.5e-233 775.7 0.2 3.9e-233 775.1 0.2 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KRZ99701.1 - 2.5e-25 89.2 0.2 8.7e-25 87.5 0.0 2.0 3 0 0 3 3 3 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KRZ99701.1 - 2.2e-16 59.6 0.5 2.1e-06 26.8 0.0 3.3 3 0 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 KRZ99701.1 - 0.0011 18.6 0.2 0.016 14.7 0.1 2.3 2 0 0 2 2 2 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 KRZ99701.1 - 0.0036 16.7 0.0 0.013 14.9 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain ATP_bind_3 PF01171.20 KRZ99702.1 - 6.9e-48 162.8 0.1 1.1e-47 162.1 0.1 1.3 1 0 0 1 1 1 1 PP-loop family QueC PF06508.13 KRZ99702.1 - 0.00016 21.2 0.2 0.045 13.2 0.0 3.1 2 1 0 2 2 2 1 Queuosine biosynthesis protein QueC ThiI PF02568.14 KRZ99702.1 - 0.016 14.8 0.0 0.47 10.0 0.0 2.6 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) tRNA_Me_trans PF03054.16 KRZ99702.1 - 0.043 12.6 0.0 0.093 11.5 0.0 1.7 2 0 0 2 2 2 0 tRNA methyl transferase Asn_synthase PF00733.21 KRZ99702.1 - 0.045 13.4 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Asparagine synthase Peptidase_M1_N PF17900.1 KRZ99703.1 - 0.00036 20.8 2.3 1.2 9.3 0.4 3.5 2 1 1 3 3 3 2 Peptidase M1 N-terminal domain Peptidase_M1 PF01433.20 KRZ99703.1 - 0.049 13.2 0.3 0.13 11.8 0.0 1.8 2 0 0 2 2 2 0 Peptidase family M1 domain VPS9 PF02204.18 KRZ99704.1 - 2.6e-27 95.0 1.5 3.8e-27 94.6 0.3 2.0 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 KRZ99704.1 - 1.1e-12 48.0 0.9 6.6e-12 45.6 0.4 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF5601) CUE PF02845.16 KRZ99704.1 - 0.0012 18.5 0.0 0.0026 17.4 0.0 1.6 1 0 0 1 1 1 1 CUE domain Ndc80_HEC PF03801.13 KRZ99706.1 - 4e-48 162.9 2.6 4e-48 162.9 2.6 2.3 2 0 0 2 2 2 1 HEC/Ndc80p family DUF5595 PF18077.1 KRZ99706.1 - 2.6e-09 37.0 6.8 2.6e-09 37.0 6.8 5.1 5 2 0 6 6 6 1 Domain of unknown function (DUF5595) FliJ PF02050.16 KRZ99706.1 - 1.3e-05 25.4 1.2 1.3e-05 25.4 1.2 4.8 4 1 2 6 6 6 1 Flagellar FliJ protein BK_channel_a PF03493.18 KRZ99706.1 - 0.086 13.0 1.2 5.6 7.2 0.1 2.8 2 0 0 2 2 2 0 Calcium-activated BK potassium channel alpha subunit ApoO PF09769.9 KRZ99706.1 - 0.46 10.4 3.8 36 4.3 0.1 3.6 3 1 0 3 3 3 0 Apolipoprotein O Nucleoporin_FG2 PF15967.5 KRZ99706.1 - 0.48 8.9 5.5 4.2 5.8 0.4 2.3 2 0 0 2 2 2 0 Nucleoporin FG repeated region APG6_N PF17675.1 KRZ99706.1 - 4 8.0 45.6 0.24 11.9 8.3 4.9 3 2 1 4 4 4 0 Apg6 coiled-coil region DUF4351 PF14261.6 KRZ99706.1 - 9.1 6.4 11.3 16 5.6 0.1 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4351) MRP-L20 PF12824.7 KRZ99707.1 - 1.1e-48 165.5 4.1 1.3e-48 165.3 4.1 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 HTH_11 PF08279.12 KRZ99707.1 - 0.089 12.7 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 HTH domain HTH_32 PF13565.6 KRZ99707.1 - 0.11 13.1 0.0 0.26 12.0 0.0 1.7 1 0 0 1 1 1 0 Homeodomain-like domain C2 PF00168.30 KRZ99709.1 - 3.9e-12 46.4 0.0 8.3e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 C2 domain DUF4833 PF16117.5 KRZ99709.1 - 0.04 13.9 0.0 0.074 13.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4833) RNA_pol_3_Rpc31 PF11705.8 KRZ99710.1 - 1.1e-48 166.4 11.2 1.4e-48 166.1 11.2 1.0 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 PPP4R2 PF09184.11 KRZ99710.1 - 0.12 12.0 11.7 0.14 11.7 11.7 1.2 1 0 0 1 1 1 0 PPP4R2 TFIIA PF03153.13 KRZ99710.1 - 0.13 12.3 9.1 0.16 11.9 9.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit WD40 PF00400.32 KRZ99711.1 - 9.8e-15 54.7 7.3 6.8e-05 23.6 0.8 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KRZ99711.1 - 0.0042 17.3 0.0 0.27 11.6 0.0 3.5 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain PGA2 PF07543.12 KRZ99712.1 - 1.8e-06 28.0 15.5 0.00087 19.3 15.5 2.0 1 1 0 1 1 1 1 Protein trafficking PGA2 O-antigen_lig PF13425.6 KRZ99712.1 - 0.033 13.0 1.7 0.036 12.9 1.7 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Nicastrin PF05450.15 KRZ99712.1 - 0.091 12.2 0.1 0.11 11.9 0.1 1.1 1 0 0 1 1 1 0 Nicastrin SPOUT_MTase PF02590.17 KRZ99712.1 - 0.13 12.3 2.0 0.16 11.9 2.0 1.1 1 0 0 1 1 1 0 Predicted SPOUT methyltransferase DUF4169 PF13770.6 KRZ99712.1 - 0.3 11.4 5.4 0.25 11.6 4.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4169) Ubiquitin_2 PF14560.6 KRZ99713.1 - 1e-24 86.8 0.3 2e-24 85.9 0.3 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain CAP_GLY PF01302.25 KRZ99713.1 - 1.6e-21 76.1 0.3 2.5e-21 75.5 0.3 1.3 1 0 0 1 1 1 1 CAP-Gly domain UPRTase PF14681.6 KRZ99714.1 - 1.3e-75 253.4 0.0 1.7e-75 253.0 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 KRZ99714.1 - 0.075 12.5 0.0 0.098 12.2 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase domain Flu_C_NS1 PF03506.13 KRZ99714.1 - 0.17 11.8 0.1 0.28 11.2 0.1 1.2 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) Actin PF00022.19 KRZ99715.1 - 1.6e-126 422.3 0.0 6.3e-126 420.3 0.0 1.7 1 1 0 1 1 1 1 Actin EF-hand_6 PF13405.6 KRZ99716.1 - 0.00096 18.9 0.9 0.018 14.9 0.0 3.1 4 0 0 4 4 4 1 EF-hand domain EF-hand_8 PF13833.6 KRZ99716.1 - 0.025 14.4 0.5 0.14 12.0 0.1 2.4 3 0 0 3 3 3 0 EF-hand domain pair EF-hand_9 PF14658.6 KRZ99716.1 - 0.064 13.6 0.1 0.12 12.8 0.1 1.5 1 0 0 1 1 1 0 EF-hand domain RNA_pol_Rpb6 PF01192.22 KRZ99717.1 - 1.4e-16 60.1 0.1 2e-16 59.6 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb6 Peptidase_M16 PF00675.20 KRZ99718.1 - 1e-16 61.3 0.1 1.5e-16 60.7 0.1 1.2 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KRZ99718.1 - 5.6e-05 23.2 0.0 0.0001 22.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain PIG-U PF06728.13 KRZ99719.1 - 1.1e-112 376.9 30.1 1.2e-112 376.7 30.1 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U LSM PF01423.22 KRZ99720.1 - 7.2e-07 28.8 0.2 9.2e-07 28.5 0.2 1.2 1 0 0 1 1 1 1 LSM domain NCBP3 PF10309.9 KRZ99721.1 - 2.6e-27 94.4 0.1 6e-27 93.3 0.1 1.6 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 RNA_bind PF08675.11 KRZ99721.1 - 0.015 15.3 0.1 0.037 14.0 0.1 1.7 1 0 0 1 1 1 0 RNA binding domain AAA PF00004.29 KRZ99722.1 - 5.3e-42 143.4 0.0 1e-41 142.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 KRZ99722.1 - 4.3e-29 100.3 0.1 1.2e-28 98.9 0.1 1.8 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 KRZ99722.1 - 1.9e-22 79.1 5.7 1.9e-22 79.1 5.7 1.9 2 0 0 2 2 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 KRZ99722.1 - 5.1e-07 29.4 0.0 2.8e-06 27.0 0.0 2.4 2 0 0 2 2 1 1 AAA+ lid domain AAA_16 PF13191.6 KRZ99722.1 - 1.8e-06 28.5 0.4 0.00014 22.3 0.1 3.1 2 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KRZ99722.1 - 1.1e-05 25.3 0.0 1.7e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KRZ99722.1 - 1.8e-05 24.8 0.0 8.5e-05 22.6 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 KRZ99722.1 - 2.6e-05 24.6 2.3 0.012 15.9 0.0 4.1 5 0 0 5 5 4 1 RNA helicase DUF815 PF05673.13 KRZ99722.1 - 3e-05 23.3 0.0 8e-05 21.9 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 KRZ99722.1 - 3.2e-05 24.2 0.5 0.012 15.9 0.0 2.8 2 1 1 3 3 2 1 AAA domain IstB_IS21 PF01695.17 KRZ99722.1 - 6.2e-05 22.8 0.0 0.00021 21.1 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_14 PF13173.6 KRZ99722.1 - 0.00019 21.5 0.1 0.001 19.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 KRZ99722.1 - 0.0006 19.1 0.0 0.0014 18.0 0.0 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 KRZ99722.1 - 0.00061 20.0 0.0 0.0018 18.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KRZ99722.1 - 0.0014 19.2 0.0 0.0045 17.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KRZ99722.1 - 0.0015 18.3 0.1 0.0088 15.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.14 KRZ99722.1 - 0.0027 17.9 0.0 0.0099 16.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.6 KRZ99722.1 - 0.012 16.1 0.6 0.054 13.9 0.0 2.4 3 1 0 3 3 2 0 AAA domain Sigma54_activat PF00158.26 KRZ99722.1 - 0.014 15.1 0.0 0.083 12.6 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain ATPase PF06745.13 KRZ99722.1 - 0.015 14.6 0.4 4.2 6.6 0.0 3.0 2 1 1 3 3 3 0 KaiC NACHT PF05729.12 KRZ99722.1 - 0.018 15.0 0.1 0.39 10.6 0.0 2.5 2 1 1 3 3 2 0 NACHT domain AAA_25 PF13481.6 KRZ99722.1 - 0.025 14.2 0.1 0.4 10.2 0.1 2.3 1 1 1 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KRZ99722.1 - 0.029 13.8 0.0 0.08 12.3 0.0 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 KRZ99722.1 - 0.044 13.3 0.0 0.14 11.6 0.0 1.9 1 1 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 KRZ99722.1 - 0.069 12.6 0.1 0.15 11.5 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein Parvo_NS1 PF01057.17 KRZ99722.1 - 0.07 12.2 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Zeta_toxin PF06414.12 KRZ99722.1 - 0.08 12.2 0.2 1.1 8.5 0.1 2.4 1 1 1 2 2 2 0 Zeta toxin Bac_DnaA PF00308.18 KRZ99722.1 - 0.1 12.4 0.0 0.62 9.9 0.0 2.1 1 1 0 1 1 1 0 Bacterial dnaA protein DUF2098 PF09871.9 KRZ99722.1 - 0.26 11.6 2.5 0.72 10.2 2.5 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2098) MFS_1 PF07690.16 KRZ99723.1 - 4.4e-16 58.7 45.0 4.4e-16 58.7 45.0 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily SLATT_5 PF18160.1 KRZ99723.1 - 0.038 13.3 0.0 0.038 13.3 0.0 3.3 3 1 1 4 4 4 0 SMODS and SLOG-associating 2TM effector domain family 5 YMF19 PF02326.15 KRZ99723.1 - 0.73 10.7 0.0 0.73 10.7 0.0 3.3 4 0 0 4 4 4 0 Plant ATP synthase F0 Ribosomal_S7 PF00177.21 KRZ99724.1 - 2.7e-36 124.5 2.7 4e-36 123.9 2.7 1.3 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e MFS_1 PF07690.16 KRZ99725.1 - 1.5e-30 106.4 22.7 1.5e-30 106.4 22.7 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily CYSTM PF12734.7 KRZ99726.1 - 1.1e-07 32.0 51.5 1.1e-05 25.6 36.8 4.4 2 2 0 2 2 2 1 Cysteine-rich TM module stress tolerance DLH PF01738.18 KRZ99727.1 - 2.5e-18 66.4 0.0 3e-18 66.2 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Thioredoxin PF00085.20 KRZ99728.1 - 1.6e-25 89.1 0.2 1.2e-23 83.0 0.1 2.5 2 0 0 2 2 2 1 Thioredoxin OST3_OST6 PF04756.13 KRZ99728.1 - 4.3e-10 39.4 0.1 7e-10 38.7 0.1 1.3 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 KRZ99728.1 - 1.6e-07 31.7 0.2 4.4e-07 30.3 0.2 1.7 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KRZ99728.1 - 5.4e-06 26.6 0.8 0.034 14.5 0.1 3.6 2 2 1 3 3 3 2 Thioredoxin-like TraF PF13728.6 KRZ99728.1 - 0.00016 21.6 0.0 0.00027 20.8 0.0 1.3 1 0 0 1 1 1 1 F plasmid transfer operon protein ERp29_N PF07912.13 KRZ99728.1 - 0.0002 21.5 0.2 0.00043 20.4 0.2 1.6 1 0 0 1 1 1 1 ERp29, N-terminal domain NOG1_N PF17835.1 KRZ99728.1 - 0.0063 16.5 0.1 2.8 7.9 0.0 2.5 2 0 0 2 2 2 2 NOG1 N-terminal helical domain AhpC-TSA PF00578.21 KRZ99728.1 - 0.0076 16.2 0.2 0.037 13.9 0.1 2.0 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.10 KRZ99728.1 - 0.043 13.5 0.1 0.094 12.4 0.1 1.5 1 0 0 1 1 1 0 Redoxin Thioredoxin_7 PF13899.6 KRZ99728.1 - 0.052 13.7 0.1 0.23 11.6 0.0 2.1 2 1 0 2 2 2 0 Thioredoxin-like Thioredoxin_9 PF14595.6 KRZ99728.1 - 0.078 12.8 0.1 0.42 10.4 0.0 2.2 2 1 1 3 3 3 0 Thioredoxin FSH1 PF03959.13 KRZ99729.1 - 1e-64 218.1 0.0 1.3e-64 217.7 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 KRZ99729.1 - 0.055 13.3 0.4 3.9 7.2 0.8 2.6 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase DLH PF01738.18 KRZ99729.1 - 0.14 11.7 0.0 0.3 10.6 0.0 1.5 1 1 0 1 1 1 0 Dienelactone hydrolase family HalX PF08663.10 KRZ99731.1 - 0.097 13.0 1.2 0.36 11.2 0.9 2.0 2 0 0 2 2 2 0 HalX domain Peptidase_M20 PF01546.28 KRZ99732.1 - 7.2e-31 107.5 0.0 1.1e-30 107.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KRZ99732.1 - 9.9e-13 48.0 0.0 2.2e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KRZ99732.1 - 0.0081 15.9 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 IF4E PF01652.18 KRZ99733.1 - 9.3e-26 90.5 5.5 2.4e-25 89.2 5.5 1.8 1 1 0 1 1 1 1 Eukaryotic initiation factor 4E GATA PF00320.27 KRZ99734.1 - 2.3e-15 55.9 4.6 4.5e-15 55.0 4.6 1.5 1 0 0 1 1 1 1 GATA zinc finger Auto_anti-p27 PF06677.12 KRZ99734.1 - 0.24 11.6 0.8 0.39 10.9 0.8 1.3 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) AdoHcyase PF05221.17 KRZ99735.1 - 9.7e-130 432.1 0.0 2.3e-74 250.3 0.1 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 KRZ99735.1 - 1.4e-82 275.5 2.1 2.4e-82 274.8 2.1 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 KRZ99735.1 - 1.5e-07 31.0 0.1 3.8e-07 29.6 0.1 1.7 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 KRZ99735.1 - 0.021 14.4 0.2 0.037 13.6 0.2 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 KRZ99735.1 - 0.086 13.1 0.1 0.19 12.0 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain Ribonuclease_T2 PF00445.18 KRZ99736.1 - 8.1e-39 133.7 1.6 8.1e-39 133.7 1.6 1.7 2 0 0 2 2 2 1 Ribonuclease T2 family MARVEL PF01284.23 KRZ99737.1 - 4.4e-09 36.5 6.6 6.5e-09 36.0 6.6 1.3 1 0 0 1 1 1 1 Membrane-associating domain zf_C2H2_13 PF18508.1 KRZ99738.1 - 0.022 14.3 0.1 0.042 13.4 0.1 1.5 1 0 0 1 1 1 0 Zinc finger domain RIO1 PF01163.22 KRZ99739.1 - 2.4e-10 40.3 0.0 3.7e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KRZ99739.1 - 1.1e-09 38.0 0.0 2.6e-09 36.7 0.0 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KRZ99739.1 - 1.2e-08 34.7 0.1 1.6e-08 34.3 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KRZ99739.1 - 1.6e-07 30.9 0.0 2.1e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KRZ99739.1 - 9.4e-07 29.0 0.0 1.9e-05 24.7 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family WaaY PF06176.11 KRZ99739.1 - 0.0016 18.1 0.0 0.0027 17.3 0.0 1.4 1 1 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) Choline_kinase PF01633.20 KRZ99739.1 - 0.0096 15.5 0.2 0.017 14.8 0.2 1.5 1 1 0 1 1 1 1 Choline/ethanolamine kinase DUF4135 PF13575.6 KRZ99739.1 - 0.01 15.2 0.1 0.051 12.9 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4135) EcKinase PF02958.20 KRZ99739.1 - 0.025 13.9 0.2 0.033 13.5 0.2 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase DUF1679 PF07914.11 KRZ99739.1 - 0.042 12.7 0.1 0.092 11.6 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1679) CLTH PF10607.9 KRZ99740.1 - 2.8e-09 37.0 10.2 1e-08 35.2 10.2 2.0 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.28 KRZ99740.1 - 0.00015 21.8 0.1 0.00015 21.8 0.1 2.3 2 1 0 2 2 2 1 SPRY domain DUF1870 PF08965.10 KRZ99740.1 - 0.097 12.7 0.1 0.31 11.1 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1870) HHH PF00633.23 KRZ99741.1 - 0.0069 16.2 0.0 0.017 15.0 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif HPD PF05044.12 KRZ99741.1 - 0.014 15.3 0.3 0.11 12.4 0.6 2.1 1 1 1 2 2 2 0 Homeo-prospero domain 60KD_IMP PF02096.20 KRZ99742.1 - 5.4e-14 52.4 7.1 2e-13 50.6 1.6 2.1 2 0 0 2 2 2 2 60Kd inner membrane protein Spt4 PF06093.13 KRZ99743.1 - 1.8e-30 104.9 0.1 2.1e-30 104.6 0.1 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger WG_beta_rep PF14903.6 KRZ99743.1 - 0.086 13.1 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 WG containing repeat AAA PF00004.29 KRZ99744.1 - 4.4e-51 172.7 0.0 3.8e-42 143.8 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KRZ99744.1 - 4.6e-09 35.9 0.0 1.2e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 KRZ99744.1 - 3.3e-06 27.3 0.0 2e-05 24.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 KRZ99744.1 - 1.5e-05 24.9 0.0 0.00013 21.8 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein Sigma54_activ_2 PF14532.6 KRZ99744.1 - 1.6e-05 25.0 0.0 0.2 11.8 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_16 PF13191.6 KRZ99744.1 - 3.1e-05 24.4 3.1 6.3e-05 23.4 0.1 3.0 5 1 0 5 5 2 1 AAA ATPase domain AAA_5 PF07728.14 KRZ99744.1 - 0.00039 20.4 0.0 0.0032 17.5 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Bromodomain PF00439.25 KRZ99744.1 - 0.001 19.1 0.2 0.0038 17.3 0.2 2.0 1 0 0 1 1 1 1 Bromodomain AAA_14 PF13173.6 KRZ99744.1 - 0.0013 18.8 0.5 0.026 14.6 0.0 3.3 3 0 0 3 3 3 1 AAA domain Sigma54_activat PF00158.26 KRZ99744.1 - 0.0021 17.8 0.0 0.8 9.4 0.0 3.0 3 0 0 3 3 3 1 Sigma-54 interaction domain RNA_helicase PF00910.22 KRZ99744.1 - 0.0027 18.1 0.1 0.06 13.7 0.0 3.1 3 0 0 3 3 3 1 RNA helicase AAA_22 PF13401.6 KRZ99744.1 - 0.0048 17.2 1.5 0.16 12.3 0.3 3.5 2 2 1 3 3 3 1 AAA domain TIP49 PF06068.13 KRZ99744.1 - 0.0084 15.4 0.0 0.14 11.4 0.0 2.2 2 0 0 2 2 2 1 TIP49 P-loop domain ABC_tran PF00005.27 KRZ99744.1 - 0.013 16.1 1.5 0.084 13.4 0.0 3.2 4 0 0 4 4 3 0 ABC transporter Mg_chelatase PF01078.21 KRZ99744.1 - 0.013 14.9 0.0 0.1 12.0 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ResIII PF04851.15 KRZ99744.1 - 0.018 15.1 0.0 0.018 15.1 0.0 3.2 4 0 0 4 4 3 0 Type III restriction enzyme, res subunit AAA_7 PF12775.7 KRZ99744.1 - 0.02 14.4 0.0 0.18 11.3 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_33 PF13671.6 KRZ99744.1 - 0.028 14.6 0.0 0.075 13.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KRZ99744.1 - 0.072 13.6 2.2 0.15 12.6 0.0 2.9 3 0 0 3 3 1 0 AAA domain PhoH PF02562.16 KRZ99744.1 - 0.072 12.5 0.0 0.28 10.6 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein RuvB_N PF05496.12 KRZ99744.1 - 0.072 12.8 0.0 0.21 11.3 0.0 1.8 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 KRZ99744.1 - 0.093 12.6 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 KRZ99744.1 - 0.098 12.2 0.0 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KRZ99744.1 - 0.14 11.8 0.0 0.33 10.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain IZUMO PF15005.6 KRZ99744.1 - 0.34 11.4 5.3 0.93 10.0 1.2 2.7 2 0 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated AAA_11 PF13086.6 KRZ99744.1 - 0.43 10.3 0.0 0.43 10.3 0.0 4.4 4 1 0 4 4 3 0 AAA domain tRNA-synt_1g PF09334.11 KRZ99745.1 - 1e-97 327.3 1.9 1.4e-96 323.7 0.5 2.6 2 1 0 2 2 2 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KRZ99745.1 - 6.7e-23 80.8 0.1 4.4e-11 41.8 0.0 4.0 1 1 2 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 KRZ99745.1 - 2.4e-10 40.2 0.1 0.00067 19.1 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 KRZ99745.1 - 0.012 14.6 0.0 0.02 13.8 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (K) HTH_1 PF00126.27 KRZ99745.1 - 0.045 13.7 0.0 0.18 11.8 0.0 2.0 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family Yip1 PF04893.17 KRZ99746.1 - 2.1e-10 40.6 16.8 3.4e-10 39.9 16.8 1.4 1 0 0 1 1 1 1 Yip1 domain BRCT PF00533.26 KRZ99747.1 - 1.2e-32 112.1 11.8 1.6e-11 44.4 0.5 5.0 4 1 0 4 4 4 4 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KRZ99747.1 - 2.1e-22 78.8 4.5 2.7e-10 40.0 0.0 5.5 5 0 0 5 5 5 5 twin BRCT domain BRCT_2 PF16589.5 KRZ99747.1 - 1.7e-15 57.2 3.0 1.4e-05 25.4 0.1 4.4 4 0 0 4 4 4 2 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 KRZ99747.1 - 0.018 15.3 2.8 0.38 11.1 0.0 3.4 3 0 0 3 3 3 0 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 KRZ99747.1 - 0.28 11.3 1.5 2.1 8.4 0.0 2.9 3 0 0 3 3 3 0 BRCA1 C Terminus (BRCT) domain Flocculin_t3 PF13928.6 KRZ99748.1 - 0.003 18.0 41.5 0.015 15.8 11.1 3.6 1 1 3 4 4 4 2 Flocculin type 3 repeat PLU-1 PF08429.11 KRZ99749.1 - 2.4e-62 211.1 7.1 2.4e-62 211.1 7.1 3.0 3 0 0 3 3 3 1 PLU-1-like protein JmjC PF02373.22 KRZ99749.1 - 3.9e-21 75.6 2.0 5.8e-10 39.6 0.1 3.4 2 0 0 2 2 2 2 JmjC domain, hydroxylase ARID PF01388.21 KRZ99749.1 - 5.8e-16 58.9 0.1 5.3e-15 55.9 0.0 2.8 2 0 0 2 2 1 1 ARID/BRIGHT DNA binding domain PHD PF00628.29 KRZ99749.1 - 1.2e-07 31.5 9.6 2.4e-07 30.5 9.6 1.5 1 0 0 1 1 1 1 PHD-finger JmjN PF02375.17 KRZ99749.1 - 1.8e-06 27.8 0.0 5.6e-06 26.2 0.0 2.0 1 0 0 1 1 1 1 jmjN domain VGPC1_C PF16799.5 KRZ99749.1 - 0.0043 17.0 0.1 0.55 10.3 0.1 3.6 3 0 0 3 3 3 1 C-terminal membrane-localisation domain of ion-channel, VCN1 zf-HC5HC2H PF13771.6 KRZ99749.1 - 0.064 13.5 8.9 0.015 15.5 4.9 2.0 2 0 0 2 2 2 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 KRZ99749.1 - 0.078 13.1 2.4 0.22 11.7 2.4 1.7 1 0 0 1 1 1 0 PHD-zinc-finger like domain C1_1 PF00130.22 KRZ99749.1 - 0.093 12.6 2.7 0.19 11.6 2.7 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_4 PF16866.5 KRZ99749.1 - 0.46 10.6 9.5 1.2 9.2 8.4 2.2 2 0 0 2 2 2 0 PHD-finger zf-RING_2 PF13639.6 KRZ99749.1 - 0.5 10.8 7.2 1.1 9.7 7.2 1.5 1 0 0 1 1 1 0 Ring finger domain zf-RING_9 PF13901.6 KRZ99749.1 - 0.64 10.0 6.8 1.1 9.2 5.1 2.3 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon zf-CHY PF05495.12 KRZ99749.1 - 2.1 8.9 6.6 4.2 7.9 6.6 1.4 1 0 0 1 1 1 0 CHY zinc finger 7TM_GPCR_Srh PF10318.9 KRZ99750.1 - 0.0043 16.1 1.8 0.0066 15.5 1.8 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srh Gin PF10764.9 KRZ99750.1 - 0.0058 16.6 0.6 0.016 15.1 0.6 1.7 1 0 0 1 1 1 1 Inhibitor of sigma-G Gin Lzipper-MIP1 PF14389.6 KRZ99750.1 - 0.05 13.9 4.9 0.067 13.5 0.8 3.1 3 1 1 4 4 4 0 Leucine-zipper of ternary complex factor MIP1 MCM_N PF14551.6 KRZ99750.1 - 0.19 12.3 6.4 0.17 12.5 3.4 2.2 1 1 1 2 2 2 0 MCM N-terminal domain TMF_DNA_bd PF12329.8 KRZ99750.1 - 0.28 11.2 26.7 0.92 9.5 6.2 3.8 2 2 2 4 4 4 0 TATA element modulatory factor 1 DNA binding DUF641 PF04859.12 KRZ99750.1 - 0.39 11.1 14.0 1.3 9.4 2.8 2.6 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Glyco_hydro_65m PF03632.15 KRZ99750.1 - 0.79 8.5 7.2 1.2 7.9 7.2 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65 central catalytic domain IZUMO PF15005.6 KRZ99750.1 - 2.3 8.7 11.5 4.8 7.7 0.6 2.3 1 1 1 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated SlyX PF04102.12 KRZ99750.1 - 2.9 8.6 8.1 5.5 7.7 4.7 2.7 2 0 0 2 2 2 0 SlyX Syntaxin-6_N PF09177.11 KRZ99750.1 - 3.4 8.3 8.0 13 6.4 8.0 2.1 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Ribosomal_L30_N PF08079.12 KRZ99751.1 - 4e-23 81.4 17.7 7e-23 80.7 17.7 1.4 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 KRZ99751.1 - 4.2e-17 61.8 1.0 1.2e-16 60.3 1.0 1.8 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_L18p PF00861.22 KRZ99751.1 - 0.00033 21.0 1.6 0.00061 20.2 1.6 1.4 1 0 0 1 1 1 1 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast Peptidase_S10 PF00450.22 KRZ99752.1 - 9.4e-126 420.6 0.1 9.4e-126 420.6 0.1 1.5 2 0 0 2 2 2 1 Serine carboxypeptidase COX14 PF14880.6 KRZ99754.1 - 6.3e-16 58.0 0.0 7.5e-16 57.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c assembly Chordopox_A13L PF05961.11 KRZ99754.1 - 0.031 14.5 0.0 0.039 14.2 0.0 1.2 1 0 0 1 1 1 0 Chordopoxvirus A13L protein Rtf2 PF04641.12 KRZ99755.1 - 1.8e-27 96.4 2.9 3.2e-27 95.6 2.9 1.4 1 1 0 1 1 1 1 Rtf2 RING-finger zf-NOSIP PF15906.5 KRZ99755.1 - 0.019 15.1 0.1 0.019 15.1 0.1 2.4 3 0 0 3 3 3 0 Zinc-finger of nitric oxide synthase-interacting protein DNA_pol_B_thumb PF14791.6 KRZ99755.1 - 0.03 14.5 0.0 0.12 12.6 0.0 2.0 2 0 0 2 2 2 0 DNA polymerase beta thumb DUF1610 PF07754.11 KRZ99755.1 - 0.031 14.3 2.2 0.066 13.2 2.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1610) zf-AN1 PF01428.16 KRZ99755.1 - 0.11 12.7 1.0 0.21 11.8 1.0 1.4 1 0 0 1 1 1 0 AN1-like Zinc finger C1_4 PF07975.12 KRZ99755.1 - 0.18 12.1 2.0 0.47 10.7 2.0 1.7 1 0 0 1 1 1 0 TFIIH C1-like domain Prefoldin PF02996.17 KRZ99756.1 - 5.8e-21 74.6 5.7 7.5e-21 74.3 5.7 1.2 1 0 0 1 1 1 1 Prefoldin subunit Uteroglobin PF01099.17 KRZ99756.1 - 0.0083 16.4 2.7 0.28 11.6 0.1 2.2 2 0 0 2 2 2 2 Uteroglobin family SYCE1 PF15233.6 KRZ99756.1 - 0.015 15.4 5.3 0.015 15.4 5.3 2.1 2 0 0 2 2 2 0 Synaptonemal complex central element protein 1 CLZ PF16526.5 KRZ99756.1 - 0.081 13.3 0.4 0.081 13.3 0.4 2.4 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4988 PF16378.5 KRZ99756.1 - 0.41 10.3 5.6 2.3 7.8 2.3 2.1 2 0 0 2 2 2 0 Domain of unknown function Rad10 PF03834.14 KRZ99757.1 - 2.6e-42 143.5 1.8 3.2e-42 143.2 0.7 1.7 2 0 0 2 2 2 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) LPP PF04728.13 KRZ99757.1 - 0.008 16.5 1.3 0.008 16.5 1.3 2.4 2 0 0 2 2 2 1 Lipoprotein leucine-zipper Pkinase_fungal PF17667.1 KRZ99757.1 - 0.056 12.2 0.5 0.072 11.9 0.5 1.3 1 0 0 1 1 1 0 Fungal protein kinase Mif2_N PF15624.6 KRZ99757.1 - 0.34 11.6 6.2 0.54 11.0 6.2 1.3 1 0 0 1 1 1 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal TMEM51 PF15345.6 KRZ99757.1 - 0.49 10.2 8.1 0.78 9.5 8.1 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 Enolase_C PF00113.22 KRZ99758.1 - 7.1e-150 498.2 0.0 1.1e-149 497.6 0.0 1.3 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 KRZ99758.1 - 2.7e-57 192.5 0.2 4.7e-57 191.8 0.2 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 KRZ99758.1 - 0.00049 19.7 0.0 0.00074 19.1 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 KRZ99758.1 - 0.037 13.2 0.1 0.17 11.0 0.0 1.9 2 0 0 2 2 2 0 Methylaspartate ammonia-lyase C-terminus RRM_2 PF04059.12 KRZ99758.1 - 0.1 12.8 0.2 0.96 9.7 0.0 2.5 2 1 1 3 3 3 0 RNA recognition motif 2 Acetyltransf_1 PF00583.25 KRZ99759.1 - 5.4e-11 42.7 0.0 6.7e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KRZ99759.1 - 1.8e-06 27.9 0.0 3.7e-06 26.9 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KRZ99759.1 - 0.00094 19.9 0.0 0.0014 19.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KRZ99759.1 - 0.0021 18.5 0.0 0.0029 18.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Fer2_3 PF13085.6 KRZ99759.1 - 0.0022 18.0 0.0 0.0044 17.0 0.0 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Mss4 PF04421.13 KRZ99759.1 - 0.02 15.0 0.1 0.046 13.9 0.1 1.6 1 1 0 1 1 1 0 Mss4 protein Glyco_hydro_76 PF03663.14 KRZ99760.1 - 4.7e-28 98.8 15.3 7.6e-28 98.1 15.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 PAP1 PF08601.10 KRZ99760.1 - 8.2 6.0 13.4 14 5.2 13.4 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 DUF3584 PF12128.8 KRZ99762.1 - 0.00036 18.2 17.4 0.00055 17.6 17.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) TPR_MLP1_2 PF07926.12 KRZ99762.1 - 0.0011 19.0 10.7 0.0011 19.0 10.7 2.5 1 1 0 2 2 2 1 TPR/MLP1/MLP2-like protein DUF4250 PF14056.6 KRZ99762.1 - 0.0092 15.9 0.5 0.027 14.4 0.5 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4250) Golgin_A5 PF09787.9 KRZ99762.1 - 0.015 14.8 23.8 0.051 13.0 4.2 2.4 1 1 1 2 2 2 0 Golgin subfamily A member 5 DUF745 PF05335.13 KRZ99762.1 - 0.039 13.7 11.6 0.018 14.8 5.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF745) APG6_N PF17675.1 KRZ99762.1 - 0.083 13.4 21.6 21 5.6 21.6 2.5 1 1 0 1 1 1 0 Apg6 coiled-coil region CALCOCO1 PF07888.11 KRZ99762.1 - 0.53 9.1 20.3 0.64 8.8 8.1 2.1 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like HSBP1 PF06825.12 KRZ99762.1 - 0.75 9.7 10.8 0.19 11.6 1.0 3.4 3 0 0 3 3 3 0 Heat shock factor binding protein 1 HIP1_clath_bdg PF16515.5 KRZ99762.1 - 0.9 10.2 18.3 1.3 9.7 5.6 2.9 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF2383 PF09537.10 KRZ99762.1 - 2.5 8.5 6.5 1.8 8.9 0.7 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF2383) Phage_GPO PF05929.11 KRZ99762.1 - 2.5 7.6 12.1 0.21 11.2 5.1 2.2 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Spc7 PF08317.11 KRZ99762.1 - 2.9 6.7 25.2 2.5 6.9 10.0 2.4 1 1 1 2 2 2 0 Spc7 kinetochore protein Fez1 PF06818.15 KRZ99762.1 - 4.9 7.6 20.9 1.8 8.9 9.5 2.5 1 1 1 2 2 2 0 Fez1 Flavin_Reduct PF01613.18 KRZ99763.1 - 6.6e-24 84.7 0.0 9e-24 84.3 0.0 1.2 1 0 0 1 1 1 1 Flavin reductase like domain FEZ PF07763.13 KRZ99763.1 - 0.028 14.2 0.1 0.037 13.8 0.1 1.2 1 0 0 1 1 1 0 FEZ-like protein SKN1 PF03935.15 KRZ99764.1 - 2.2e-62 211.1 2.1 2.4e-62 211.0 2.1 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) ketoacyl-synt PF00109.26 KRZ99765.1 - 2.7e-58 197.5 0.0 2e-57 194.7 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KRZ99765.1 - 5.8e-37 126.3 0.1 9.7e-37 125.6 0.1 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 KRZ99765.1 - 0.00019 20.9 0.1 0.0021 17.5 0.0 2.1 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KRZ99765.1 - 0.00047 19.8 0.2 0.16 11.6 0.1 2.6 2 0 0 2 2 2 2 Thiolase, C-terminal domain FF PF01846.19 KRZ99766.1 - 0.0058 16.8 2.3 0.012 15.8 0.6 2.6 2 0 0 2 2 2 1 FF domain Caldesmon PF02029.15 KRZ99766.1 - 0.11 11.3 26.3 0.13 11.0 26.3 1.2 1 0 0 1 1 1 0 Caldesmon zf-C2H2 PF00096.26 KRZ99767.1 - 4e-11 42.7 8.5 2.8e-05 24.3 0.3 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KRZ99767.1 - 7.5e-08 32.6 7.2 0.00046 20.8 0.3 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger DUF2321 PF10083.9 KRZ99767.1 - 0.00058 19.5 0.0 0.0012 18.5 0.0 1.6 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2321) zf-C2H2_jaz PF12171.8 KRZ99767.1 - 0.00076 19.7 0.3 0.15 12.4 0.4 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 KRZ99767.1 - 0.0027 18.1 8.9 0.16 12.4 1.4 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_3rep PF18868.1 KRZ99767.1 - 0.0047 17.6 0.9 0.56 10.9 0.2 2.2 1 1 1 2 2 2 2 Zinc finger C2H2-type, 3 repeats zf-met PF12874.7 KRZ99767.1 - 0.016 15.6 0.8 9.6 6.8 0.7 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KRZ99767.1 - 0.021 14.9 3.0 0.17 11.9 0.7 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger Actin_micro PF17003.5 KRZ99767.1 - 0.033 13.4 0.3 0.096 11.8 0.3 1.7 1 1 0 1 1 1 0 Putative actin-like family zf_C2H2_ZHX PF18387.1 KRZ99767.1 - 0.041 13.5 3.0 3 7.6 0.0 2.4 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain LIM PF00412.22 KRZ99767.1 - 0.079 13.2 1.3 0.61 10.4 1.3 2.1 1 1 0 1 1 1 0 LIM domain DUF2256 PF10013.9 KRZ99767.1 - 0.083 13.0 1.9 3.6 7.8 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) TRAF6_Z2 PF18048.1 KRZ99767.1 - 0.09 12.9 0.6 0.54 10.4 0.1 2.2 2 0 0 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 zf-Di19 PF05605.12 KRZ99767.1 - 0.1 12.9 2.3 0.26 11.6 2.4 1.6 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_11 PF16622.5 KRZ99767.1 - 0.14 11.9 0.5 0.14 11.9 0.5 2.0 2 0 0 2 2 2 0 zinc-finger C2H2-type NCA2 PF08637.10 KRZ99768.1 - 1e-91 307.1 7.6 2.2e-90 302.7 5.5 2.2 2 0 0 2 2 2 2 ATP synthase regulation protein NCA2 zf-RING_10 PF16685.5 KRZ99768.1 - 0.062 13.5 0.2 0.15 12.2 0.2 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 Proteasome PF00227.26 KRZ99769.1 - 1e-57 194.7 0.1 1.2e-57 194.5 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KRZ99769.1 - 2.2e-13 49.6 0.3 3.7e-13 48.9 0.3 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature PMBR PF09373.10 KRZ99770.1 - 0.3 11.3 0.1 0.3 11.3 0.1 3.0 3 0 0 3 3 3 0 Pseudomurein-binding repeat DUF489 PF04356.12 KRZ99770.1 - 0.74 9.8 3.5 1.3 9.0 3.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF489) DUF87 PF01935.17 KRZ99770.1 - 2.3 8.3 8.0 0.53 10.3 3.1 2.2 1 1 1 2 2 2 0 Helicase HerA, central domain Peptidase_M24 PF00557.24 KRZ99771.1 - 2e-48 164.9 0.0 2.8e-48 164.4 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KRZ99771.1 - 4e-32 110.5 0.0 7.6e-32 109.6 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain AAA_23 PF13476.6 KRZ99771.1 - 0.067 13.7 0.6 0.14 12.7 0.6 1.4 1 0 0 1 1 1 0 AAA domain Band_7 PF01145.25 KRZ99772.1 - 5.5e-23 81.9 7.0 9e-23 81.2 7.0 1.4 1 1 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 KRZ99772.1 - 0.0035 16.5 4.1 0.0043 16.2 4.1 1.1 1 0 0 1 1 1 1 SigmaW regulon antibacterial Atg14 PF10186.9 KRZ99772.1 - 0.25 10.4 3.3 0.35 9.9 3.3 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 VIT1 PF01988.19 KRZ99773.1 - 5.2e-64 216.0 2.0 7.6e-64 215.5 2.0 1.2 1 0 0 1 1 1 1 VIT family DUF533 PF04391.12 KRZ99773.1 - 0.07 12.7 0.1 0.19 11.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF533) RRM_1 PF00076.22 KRZ99774.1 - 7e-23 80.2 2.1 2.7e-10 39.9 0.3 2.5 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KRZ99774.1 - 1.5e-06 27.8 0.0 0.00057 19.5 0.1 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KRZ99774.1 - 0.0047 16.8 0.1 0.68 9.8 0.1 2.4 2 0 0 2 2 2 1 Occluded RNA-recognition motif RRM_3 PF08777.11 KRZ99774.1 - 0.0052 16.8 2.2 2.1 8.5 0.0 2.5 2 1 0 2 2 2 2 RNA binding motif Limkain-b1 PF11608.8 KRZ99774.1 - 0.024 14.7 0.0 0.093 12.8 0.0 1.9 2 0 0 2 2 2 0 Limkain b1 Nup35_RRM_2 PF14605.6 KRZ99774.1 - 0.033 14.2 0.1 1.8 8.6 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif PHM7_cyt PF14703.6 KRZ99774.1 - 0.037 14.3 1.3 2.3 8.4 0.2 2.5 2 1 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter DUF1027 PF06265.11 KRZ99774.1 - 0.068 13.2 0.1 0.18 11.8 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1027) RNA_bind PF08675.11 KRZ99774.1 - 0.14 12.2 0.0 10 6.3 0.0 2.5 2 0 0 2 2 2 0 RNA binding domain bZIP_2 PF07716.15 KRZ99775.1 - 1.2e-09 38.1 7.8 7e-09 35.6 8.5 1.9 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 KRZ99775.1 - 1.8e-09 37.6 6.6 1.8e-09 37.6 6.6 2.0 2 0 0 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.17 KRZ99775.1 - 0.021 15.3 3.3 0.051 14.1 3.3 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor ZapB PF06005.12 KRZ99775.1 - 0.037 14.5 3.1 0.11 12.9 3.1 1.8 1 0 0 1 1 1 0 Cell division protein ZapB TUG-UBL1 PF11470.8 KRZ99776.1 - 2.4e-18 66.1 2.4 1.2e-17 63.8 1.0 2.7 3 0 0 3 3 3 1 TUG ubiquitin-like domain DUF3275 PF11679.8 KRZ99776.1 - 0.65 9.9 6.0 1.4 8.8 6.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) Presenilin PF01080.17 KRZ99776.1 - 1.3 7.7 14.6 1.9 7.1 14.6 1.3 1 0 0 1 1 1 0 Presenilin CLN3 PF02487.17 KRZ99776.1 - 4.6 6.2 6.1 7.4 5.5 6.1 1.4 1 0 0 1 1 1 0 CLN3 protein Neur_chan_memb PF02932.16 KRZ99776.1 - 4.9 7.1 9.3 9.4 6.2 9.3 1.6 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Pmp3 PF01679.17 KRZ99777.1 - 3.9e-21 75.0 8.1 5.5e-21 74.5 8.1 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator TraG-D_C PF12696.7 KRZ99777.1 - 0.18 11.8 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 TraM recognition site of TraD and TraG SelP_N PF04592.14 KRZ99777.1 - 0.35 10.2 9.4 0.43 9.9 9.4 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Innate_immun PF12782.7 KRZ99777.1 - 2.2 7.7 10.0 2.5 7.5 10.0 1.1 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family Abhydrolase_1 PF00561.20 KRZ99778.1 - 8.5e-18 64.9 0.1 8.8e-12 45.2 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KRZ99778.1 - 4.5e-10 40.5 0.0 3.8e-09 37.5 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KRZ99778.1 - 9.4e-06 25.1 0.0 0.00011 21.6 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DUF915 PF06028.11 KRZ99778.1 - 0.00083 18.8 0.0 0.0019 17.6 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) PGAP1 PF07819.13 KRZ99778.1 - 0.13 11.9 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein MutS_V PF00488.21 KRZ99779.1 - 6.6e-69 231.7 0.1 1.2e-68 230.9 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_I PF01624.20 KRZ99779.1 - 6.2e-30 103.7 0.0 1.2e-29 102.8 0.0 1.5 1 0 0 1 1 1 1 MutS domain I MutS_III PF05192.18 KRZ99779.1 - 3.9e-28 99.0 4.7 1.1e-27 97.5 4.7 1.8 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.17 KRZ99779.1 - 3.6e-12 46.7 0.0 1.4e-11 44.9 0.0 2.0 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 KRZ99779.1 - 2e-06 28.0 0.9 2e-06 28.0 0.9 2.6 2 0 0 2 2 2 1 MutS family domain IV AAA_14 PF13173.6 KRZ99779.1 - 0.0032 17.5 3.9 0.0036 17.3 0.0 3.1 2 1 0 2 2 2 1 AAA domain DUF1160 PF06648.11 KRZ99779.1 - 2.1 8.4 10.7 0.066 13.2 1.1 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF1160) Ank_2 PF12796.7 KRZ99780.1 - 1.3e-21 76.9 1.6 6.8e-09 36.2 0.0 2.9 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KRZ99780.1 - 4.6e-18 65.3 3.1 4e-10 40.0 0.2 4.3 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 KRZ99780.1 - 3.6e-11 43.0 2.0 0.00089 19.6 0.0 4.3 3 1 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KRZ99780.1 - 4.6e-11 42.7 0.1 1e-05 25.7 0.0 4.8 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KRZ99780.1 - 1.4e-09 37.4 0.5 0.00051 20.3 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat DUF2433 PF10360.9 KRZ99781.1 - 5.3e-14 52.4 0.3 2e-12 47.3 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2433) Gcd10p PF04189.13 KRZ99781.1 - 0.12 11.4 1.2 0.21 10.6 1.2 1.3 1 0 0 1 1 1 0 Gcd10p family NADH_B2 PF14813.6 KRZ99782.1 - 0.0011 18.7 0.0 0.0012 18.6 0.0 1.1 1 0 0 1 1 1 1 NADH dehydrogenase 1 beta subcomplex subunit 2 SET PF00856.28 KRZ99784.1 - 9.9e-13 48.8 2.2 1.2e-12 48.5 0.6 2.0 2 1 0 2 2 2 1 SET domain HTH_21 PF13276.6 KRZ99784.1 - 0.031 14.4 0.0 0.074 13.2 0.0 1.6 1 0 0 1 1 1 0 HTH-like domain 5-FTHF_cyc-lig PF01812.20 KRZ99785.1 - 1.8e-37 129.0 0.0 2.1e-37 128.8 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Cyt-b5 PF00173.28 KRZ99786.1 - 5.8e-23 80.8 0.0 7.7e-23 80.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain UCH PF00443.29 KRZ99787.1 - 4.3e-21 75.6 40.0 1.4e-19 70.6 37.0 2.4 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUF1463 PF07316.11 KRZ99787.1 - 0.018 14.9 0.1 0.046 13.6 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1463) DUF1213 PF06740.12 KRZ99787.1 - 0.15 12.6 1.5 0.92 10.1 1.5 2.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1213) Porph_ging PF09697.10 KRZ99787.1 - 1.7 9.2 3.9 2.2 8.9 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (Porph_ging) SPX PF03105.19 KRZ99788.1 - 4.4e-44 152.0 1.2 2e-27 97.1 0.1 2.3 1 1 1 2 2 2 2 SPX domain CitMHS PF03600.16 KRZ99788.1 - 5.4e-26 91.5 65.0 1e-23 84.0 41.0 1.9 1 1 1 2 2 2 2 Citrate transporter Na_sulph_symp PF00939.19 KRZ99788.1 - 1.7e-25 90.0 41.7 2.8e-25 89.3 41.7 1.2 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region DUF4962 PF16332.5 KRZ99788.1 - 0.01 14.4 0.2 0.039 12.5 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4962) PIG-P PF08510.12 KRZ99788.1 - 0.041 13.8 0.6 0.041 13.8 0.6 2.7 2 1 0 2 2 2 0 PIG-P TFIIA_gamma_N PF02268.16 KRZ99788.1 - 0.049 13.6 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 Transcription initiation factor IIA, gamma subunit, helical domain Bac_rhodopsin PF01036.18 KRZ99789.1 - 6.9e-76 254.7 22.1 8e-76 254.5 22.1 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF1290 PF06947.12 KRZ99789.1 - 0.49 10.5 6.7 0.22 11.6 0.7 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1290) UPF0121 PF03661.13 KRZ99790.1 - 2.2e-20 73.1 14.2 3.7e-20 72.4 14.2 1.3 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0121) DUF4203 PF13886.6 KRZ99790.1 - 0.43 10.2 15.8 0.032 13.9 9.0 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4203) TMEM208_SND2 PF05620.11 KRZ99791.1 - 8.4e-53 178.6 0.4 9.4e-53 178.4 0.4 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 Phage_holin_3_6 PF07332.11 KRZ99791.1 - 0.013 15.6 0.2 0.12 12.4 0.0 2.0 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III PEMT PF04191.13 KRZ99791.1 - 0.022 15.1 0.1 0.022 15.1 0.1 1.6 2 0 0 2 2 2 0 Phospholipid methyltransferase DUF962 PF06127.11 KRZ99791.1 - 0.35 11.0 1.9 0.52 10.4 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF962) YtpI PF14007.6 KRZ99791.1 - 2.2 8.5 5.7 2.6 8.2 0.1 2.8 2 1 1 3 3 3 0 YtpI-like protein BolA PF01722.18 KRZ99792.1 - 8.6e-28 96.4 1.0 1e-27 96.2 1.0 1.1 1 0 0 1 1 1 1 BolA-like protein TEX15 PF15326.6 KRZ99792.1 - 0.084 12.6 0.2 0.099 12.3 0.2 1.0 1 0 0 1 1 1 0 Testis expressed sequence 15 Myosin_head PF00063.21 KRZ99793.1 - 8.5e-278 923.2 8.6 8.5e-278 923.2 8.6 1.8 2 0 0 2 2 2 1 Myosin head (motor domain) DIL PF01843.19 KRZ99793.1 - 4.1e-25 88.1 6.2 5.5e-25 87.6 0.3 3.1 2 0 0 2 2 2 1 DIL domain IQ PF00612.27 KRZ99793.1 - 3e-16 57.6 21.5 4.5e-05 22.9 0.1 7.0 7 0 0 7 7 7 4 IQ calmodulin-binding motif Myosin_N PF02736.19 KRZ99793.1 - 0.00016 21.5 0.2 0.0006 19.6 0.2 2.1 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain KASH_CCD PF14662.6 KRZ99793.1 - 0.00084 19.2 26.9 0.0039 17.0 26.9 2.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH AAA_22 PF13401.6 KRZ99793.1 - 0.0055 17.0 0.3 0.049 13.9 0.0 2.8 4 0 0 4 4 2 1 AAA domain AAA_16 PF13191.6 KRZ99793.1 - 0.12 12.7 1.5 0.4 11.1 0.0 2.6 3 0 0 3 3 2 0 AAA ATPase domain T6PP_N PF18572.1 KRZ99793.1 - 0.16 11.8 21.3 1.5 8.7 0.0 5.4 3 1 1 4 4 4 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain Spc7 PF08317.11 KRZ99793.1 - 0.32 9.8 27.7 0.099 11.5 22.0 2.7 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF848 PF05852.11 KRZ99793.1 - 0.48 10.5 18.6 0.041 14.0 10.2 2.9 1 1 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) ABC_tran PF00005.27 KRZ99793.1 - 0.57 10.7 4.3 0.97 9.9 0.0 3.1 2 0 0 2 2 2 0 ABC transporter APG6_N PF17675.1 KRZ99793.1 - 5 7.6 28.2 3.5e+02 1.7 28.2 3.8 1 1 0 1 1 1 0 Apg6 coiled-coil region Ribosomal_L29 PF00831.23 KRZ99793.1 - 5.5 7.0 8.1 2 8.5 0.2 3.7 1 1 1 2 2 2 0 Ribosomal L29 protein HIP1_clath_bdg PF16515.5 KRZ99793.1 - 7.2 7.3 28.3 0.18 12.4 12.1 4.6 3 1 0 4 4 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 ABC_tran_CTD PF16326.5 KRZ99793.1 - 7.5 6.9 15.2 58 4.0 9.5 3.4 1 1 1 2 2 2 0 ABC transporter C-terminal domain Peptidase_M75 PF09375.10 KRZ99793.1 - 8.3 5.8 13.2 2.2 7.7 8.4 2.3 1 1 0 2 2 2 0 Imelysin FMN_dh PF01070.18 KRZ99794.1 - 2e-115 385.6 0.0 2.4e-115 385.3 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KRZ99794.1 - 3.9e-25 87.8 0.2 1.1e-24 86.4 0.1 1.8 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 KRZ99794.1 - 1.6e-06 27.6 0.0 2.5e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KRZ99794.1 - 0.00023 20.3 0.2 0.00075 18.6 0.1 1.8 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 KRZ99794.1 - 0.0066 15.9 0.0 0.01 15.3 0.0 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.14 KRZ99794.1 - 0.098 11.9 0.0 8.7 5.6 0.0 2.2 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG Ran-binding PF05508.11 KRZ99796.1 - 2.4e-107 358.5 4.0 4e-107 357.8 4.0 1.3 1 0 0 1 1 1 1 RanGTP-binding protein PBP1_TM PF14812.6 KRZ99796.1 - 0.042 14.2 7.7 0.12 12.7 4.2 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TcpS PF17456.2 KRZ99796.1 - 0.088 12.9 4.2 0.15 12.1 2.9 2.1 2 0 0 2 2 2 0 Toxin-coregulated pilus protein S YL1 PF05764.13 KRZ99796.1 - 1.4 8.9 8.3 2.3 8.3 8.3 1.4 1 0 0 1 1 1 0 YL1 nuclear protein Astro_capsid_p PF12226.8 KRZ99796.1 - 7.8 5.5 7.7 17 4.4 7.7 1.5 1 0 0 1 1 1 0 Turkey astrovirus capsid protein SNF2_N PF00176.23 KRZ99797.1 - 1.1e-57 195.4 0.0 2e-57 194.5 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.10 KRZ99797.1 - 2.5e-48 164.6 0.3 4.6e-48 163.8 0.3 1.4 1 0 0 1 1 1 1 Rad54 N terminal Helicase_C PF00271.31 KRZ99797.1 - 3.1e-15 56.5 0.0 6.3e-15 55.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KRZ99797.1 - 8.9e-07 29.1 0.0 2.2e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KRZ99797.1 - 4.7e-06 26.0 0.0 1.1e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase HDA2-3 PF11496.8 KRZ99797.1 - 1.6e-05 24.2 0.1 0.00011 21.5 0.1 2.3 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 AAA_22 PF13401.6 KRZ99797.1 - 0.0061 16.8 0.1 0.21 11.9 0.0 2.9 2 1 0 2 2 2 1 AAA domain FAD_binding_2 PF00890.24 KRZ99798.1 - 1.9e-79 267.7 0.0 2.6e-79 267.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.28 KRZ99798.1 - 3.8e-22 78.2 0.0 3.2e-21 75.2 0.0 2.3 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.24 KRZ99798.1 - 8.3e-11 42.0 0.0 2.2e-10 40.7 0.0 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KRZ99798.1 - 6.8e-08 32.3 0.1 2e-07 30.7 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KRZ99798.1 - 4e-06 27.0 0.8 1.5e-05 25.1 0.3 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KRZ99798.1 - 4.3e-06 26.2 0.5 7.7e-05 22.1 0.1 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KRZ99798.1 - 7e-05 21.7 5.1 0.0007 18.4 0.2 2.9 4 0 0 4 4 4 2 HI0933-like protein GIDA PF01134.22 KRZ99798.1 - 0.00013 21.2 0.1 0.00038 19.6 0.0 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 KRZ99798.1 - 0.00058 19.2 0.4 0.00098 18.5 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 KRZ99798.1 - 0.0017 17.7 0.1 0.0029 16.9 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 KRZ99798.1 - 0.015 14.5 0.8 0.33 10.2 0.0 2.6 3 0 0 3 3 3 0 Thi4 family Pyr_redox_3 PF13738.6 KRZ99798.1 - 0.067 12.4 0.0 0.28 10.4 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KRZ99798.1 - 0.12 11.4 0.5 0.24 10.4 0.2 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein PdaC PF13739.6 KRZ99798.1 - 0.66 11.0 2.8 16 6.6 0.1 3.2 3 0 0 3 3 3 0 Deacetylase PdaC Actin PF00022.19 KRZ99799.1 - 1.2e-150 501.6 0.0 3.9e-150 500.0 0.0 1.6 1 1 0 1 1 1 1 Actin Synaptobrevin PF00957.21 KRZ99800.1 - 6.8e-27 93.1 0.9 7.5e-27 93.0 0.9 1.0 1 0 0 1 1 1 1 Synaptobrevin DUF1100 PF06500.11 KRZ99800.1 - 0.066 12.0 0.0 0.072 11.9 0.0 1.0 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) SNARE PF05739.19 KRZ99800.1 - 5.9 7.0 13.3 82 3.3 13.3 2.3 1 1 0 1 1 1 0 SNARE domain GCV_H PF01597.19 KRZ99801.1 - 8.3e-42 141.9 1.5 1.2e-41 141.5 1.1 1.4 2 0 0 2 2 2 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.22 KRZ99801.1 - 8e-05 22.4 0.3 0.00021 21.0 0.3 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme RnfC_N PF13375.6 KRZ99801.1 - 0.00017 21.5 0.0 0.00028 20.8 0.0 1.4 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain Gp58 PF07902.11 KRZ99801.1 - 0.049 11.9 0.2 0.064 11.5 0.2 1.1 1 0 0 1 1 1 0 gp58-like protein Vhr1 PF04001.13 KRZ99802.1 - 6.3e-43 145.0 4.5 6.3e-43 145.0 4.5 2.3 2 0 0 2 2 2 1 Transcription factor Vhr1 Ribonuclease_3 PF00636.26 KRZ99802.1 - 0.012 16.2 0.1 0.061 14.0 0.1 2.2 1 0 0 1 1 1 0 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KRZ99802.1 - 0.037 14.2 0.6 0.1 12.8 0.1 2.0 2 0 0 2 2 2 0 Ribonuclease-III-like CIDE-N PF02017.15 KRZ99802.1 - 0.14 12.2 0.0 0.4 10.7 0.0 1.7 1 0 0 1 1 1 0 CIDE-N domain Arginosuc_synth PF00764.19 KRZ99803.1 - 3.5e-159 530.2 0.0 4e-159 530.0 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 KRZ99803.1 - 9.9e-05 21.9 0.0 0.00016 21.2 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 KRZ99803.1 - 0.00036 19.5 0.0 0.00059 18.7 0.0 1.3 1 0 0 1 1 1 1 tRNA methyl transferase ArAE_2_N PF10337.9 KRZ99804.1 - 2.9e-155 517.9 9.5 5e-155 517.1 2.1 2.1 2 0 0 2 2 2 2 Putative ER transporter, 6TM, N-terminal ArAE_2 PF10334.9 KRZ99804.1 - 2.9e-78 262.9 0.1 1.9e-77 260.2 0.1 2.0 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 FUSC_2 PF13515.6 KRZ99804.1 - 1.9e-05 24.7 14.1 1.9e-05 24.7 14.1 3.8 3 1 1 4 4 4 1 Fusaric acid resistance protein-like Cupin_8 PF13621.6 KRZ99805.1 - 1.5e-08 34.7 0.1 3.8e-08 33.4 0.0 1.7 2 0 0 2 2 2 1 Cupin-like domain PHD PF00628.29 KRZ99805.1 - 1.5e-07 31.2 7.8 2.7e-07 30.4 7.8 1.4 1 0 0 1 1 1 1 PHD-finger JHD PF17811.1 KRZ99805.1 - 5.2e-07 30.2 0.7 1.5e-06 28.7 0.7 1.9 1 1 0 1 1 1 1 Jumonji helical domain JmjC PF02373.22 KRZ99805.1 - 7e-05 23.2 0.2 0.00089 19.7 0.0 2.7 2 1 0 2 2 2 1 JmjC domain, hydroxylase Cupin_1 PF00190.22 KRZ99805.1 - 0.005 16.5 0.0 0.017 14.7 0.0 1.8 2 0 0 2 2 2 1 Cupin Cupin_4 PF08007.12 KRZ99805.1 - 0.0055 16.2 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_2 PF07883.11 KRZ99805.1 - 0.028 14.1 0.0 0.12 12.1 0.0 1.9 2 0 0 2 2 2 0 Cupin domain Zf_RING PF16744.5 KRZ99805.1 - 0.05 13.7 1.5 0.14 12.3 1.5 1.8 1 0 0 1 1 1 0 KIAA1045 RING finger PHD_2 PF13831.6 KRZ99805.1 - 0.12 12.0 5.6 0.21 11.2 5.6 1.4 1 0 0 1 1 1 0 PHD-finger Cupin_3 PF05899.12 KRZ99805.1 - 0.18 11.6 0.0 0.52 10.0 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF861) PHD_4 PF16866.5 KRZ99805.1 - 0.33 11.1 7.9 0.65 10.1 7.9 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING_9 PF13901.6 KRZ99805.1 - 0.34 10.8 5.8 2.5 8.0 5.9 2.1 1 1 1 2 2 2 0 Putative zinc-RING and/or ribbon C1_1 PF00130.22 KRZ99805.1 - 2 8.3 8.9 0.26 11.2 2.7 2.3 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_2 PF13639.6 KRZ99805.1 - 3.3 8.1 9.7 9.2 6.7 9.7 1.8 1 1 0 1 1 1 0 Ring finger domain BCDHK_Adom3 PF10436.9 KRZ99806.1 - 6.3e-30 104.1 0.1 9.8e-30 103.5 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KRZ99806.1 - 8e-09 36.0 0.0 2.4e-08 34.5 0.0 1.7 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KRZ99806.1 - 3.3e-06 27.0 0.0 7.9e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 KRZ99806.1 - 0.014 15.3 0.0 0.031 14.2 0.0 1.5 1 1 0 1 1 1 0 Histidine kinase-like ATPase domain DUF2013 PF09431.10 KRZ99807.1 - 6.5e-43 146.2 8.1 6.5e-43 146.2 8.1 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF2013) DUF3729 PF12526.8 KRZ99807.1 - 0.29 12.7 11.0 0.51 11.9 11.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3729) Ank_2 PF12796.7 KRZ99808.1 - 1.4e-24 86.5 7.9 6.4e-08 33.1 0.0 4.5 3 1 2 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KRZ99808.1 - 7e-23 80.7 4.4 2.1e-07 31.4 0.0 5.3 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KRZ99808.1 - 2.2e-15 55.2 7.1 0.023 15.2 0.0 7.5 7 0 0 7 7 7 5 Ankyrin repeat SPX PF03105.19 KRZ99808.1 - 1.1e-14 55.1 27.8 1.6e-07 31.6 0.4 4.9 2 2 2 4 4 4 3 SPX domain Ank PF00023.30 KRZ99808.1 - 1.2e-13 50.8 1.1 0.013 16.0 0.1 7.0 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 KRZ99808.1 - 1.9e-12 47.1 6.2 0.24 11.8 0.0 6.3 4 1 2 6 6 6 5 Ankyrin repeats (many copies) GDPD PF03009.17 KRZ99808.1 - 0.00055 19.7 0.0 0.0018 18.1 0.0 2.0 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family DUF3425 PF11905.8 KRZ99808.1 - 0.095 12.7 0.0 2 8.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3425) Ran_BP1 PF00638.18 KRZ99809.1 - 1.6e-52 176.9 1.9 2.8e-52 176.1 1.9 1.4 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.23 KRZ99809.1 - 7.6e-05 22.6 0.4 0.00093 19.1 0.4 2.2 1 1 0 1 1 1 1 WH1 domain MecA PF05389.12 KRZ99809.1 - 0.013 15.1 5.1 0.022 14.4 5.1 1.3 1 0 0 1 1 1 0 Negative regulator of genetic competence (MecA) Myc_N PF01056.18 KRZ99809.1 - 0.016 15.2 6.7 0.017 15.0 6.7 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Cellulose_synt PF03552.14 KRZ99809.1 - 0.016 13.7 2.0 0.023 13.2 2.0 1.1 1 0 0 1 1 1 0 Cellulose synthase DUF4364 PF14277.6 KRZ99809.1 - 0.11 12.2 0.1 0.11 12.2 0.1 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4364) DUF809 PF05663.11 KRZ99809.1 - 0.16 12.1 0.2 0.16 12.1 0.2 2.2 1 1 1 2 2 1 0 Protein of unknown function (DUF809) Sec62 PF03839.16 KRZ99809.1 - 0.57 9.6 8.6 0.91 9.0 8.6 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 CENP-I PF07778.11 KRZ99809.1 - 1.5 7.4 4.2 2 7.0 4.2 1.1 1 0 0 1 1 1 0 Mis6 FAM176 PF14851.6 KRZ99809.1 - 2 8.1 6.6 3.7 7.2 6.6 1.5 1 0 0 1 1 1 0 FAM176 family Cytomega_UL84 PF06284.11 KRZ99809.1 - 5.8 5.3 8.4 9 4.6 8.4 1.3 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein CRM1_C PF08767.11 KRZ99810.1 - 4.1e-126 420.5 6.7 4.1e-126 420.5 6.7 2.8 2 1 0 2 2 2 1 CRM1 C terminal Xpo1 PF08389.12 KRZ99810.1 - 6.5e-38 130.1 5.3 6.5e-38 130.1 5.3 4.6 6 1 0 6 6 6 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 KRZ99810.1 - 1.4e-33 114.3 4.4 4.1e-33 112.8 4.4 1.9 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 KRZ99810.1 - 1.8e-28 98.4 1.6 1.8e-28 98.4 1.6 3.4 3 0 0 3 3 3 1 CRM1 / Exportin repeat 3 IBN_N PF03810.19 KRZ99810.1 - 2.1e-17 62.8 2.0 1.5e-16 60.1 0.8 3.1 2 0 0 2 2 2 1 Importin-beta N-terminal domain CRM1_repeat PF18777.1 KRZ99810.1 - 1e-14 53.7 1.4 1e-14 53.7 1.4 2.6 2 0 0 2 2 2 1 Chromosome region maintenance or exportin repeat DUF1981 PF09324.10 KRZ99810.1 - 0.019 14.8 5.4 2.9 7.8 0.0 5.4 6 0 0 6 6 6 0 Domain of unknown function (DUF1981) DUF4810 PF16068.5 KRZ99810.1 - 0.14 12.7 0.0 0.66 10.5 0.0 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4810) V-ATPase_H_C PF11698.8 KRZ99810.1 - 0.16 12.1 6.9 5 7.3 0.2 4.3 4 0 0 4 4 4 0 V-ATPase subunit H Symplekin_C PF12295.8 KRZ99810.1 - 0.48 10.5 10.7 2.9 8.0 0.0 5.2 5 1 0 5 5 5 0 Symplekin tight junction protein C terminal Ldh_1_C PF02866.18 KRZ99811.1 - 2.3e-45 154.5 0.1 3.4e-45 154.0 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 KRZ99811.1 - 5.7e-43 146.4 0.0 1.1e-42 145.4 0.0 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KRZ99811.1 - 0.059 12.4 0.0 0.09 11.8 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Trehalase PF01204.18 KRZ99812.1 - 1.7e-180 601.3 4.5 2e-180 601.0 4.5 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 KRZ99812.1 - 1.5e-17 63.0 0.7 2.9e-17 62.1 0.7 1.5 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain GH-E PF14410.6 KRZ99812.1 - 0.047 14.1 0.2 0.61 10.5 0.0 2.7 2 0 0 2 2 2 0 HNH/ENDO VII superfamily nuclease with conserved GHE residues polyprenyl_synt PF00348.17 KRZ99813.1 - 6.4e-44 149.9 0.0 5.2e-38 130.6 0.0 2.4 2 1 0 2 2 2 2 Polyprenyl synthetase Alg6_Alg8 PF03155.15 KRZ99814.1 - 4.8e-165 550.2 31.3 5.7e-165 550.0 31.3 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family TPP_enzyme_N PF02776.18 KRZ99815.1 - 6.6e-25 87.7 0.0 1.1e-24 87.0 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 KRZ99815.1 - 2.3e-24 85.7 0.0 1.3e-23 83.2 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 KRZ99815.1 - 1.8e-17 63.5 0.0 8.9e-17 61.3 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.20 KRZ99815.1 - 7e-05 21.9 0.1 0.00012 21.2 0.1 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component GatB_Yqey PF02637.18 KRZ99815.1 - 0.0053 16.7 0.7 0.22 11.4 0.1 2.4 2 0 0 2 2 2 1 GatB domain DXP_synthase_N PF13292.6 KRZ99815.1 - 0.006 15.8 0.0 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase DUF362 PF04015.12 KRZ99815.1 - 0.015 15.5 0.0 0.08 13.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF362) Fungal_trans PF04082.18 KRZ99816.1 - 1.6e-29 102.8 6.7 1.6e-29 102.8 6.7 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KRZ99816.1 - 1.3e-09 38.0 11.1 2.8e-09 36.9 11.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Presenilin PF01080.17 KRZ99816.1 - 0.65 8.7 3.6 1.1 8.0 3.6 1.3 1 0 0 1 1 1 0 Presenilin ALMT PF11744.8 KRZ99816.1 - 4.3 6.0 12.1 1.1 8.1 0.6 2.2 2 0 0 2 2 2 0 Aluminium activated malate transporter Aa_trans PF01490.18 KRZ99817.1 - 1.2e-79 268.0 39.7 1.4e-79 267.7 39.7 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.6 KRZ99817.1 - 7.5e-05 21.7 40.9 9.7e-05 21.4 40.9 1.1 1 0 0 1 1 1 1 Amino acid permease Pneumo_M2 PF07380.11 KRZ99817.1 - 7.1 7.0 8.3 13 6.2 0.3 3.0 3 0 0 3 3 3 0 Pneumovirus M2 protein Helicase_C PF00271.31 KRZ99820.1 - 1.3e-19 70.6 1.6 4.9e-18 65.5 0.5 3.1 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KRZ99820.1 - 4.4e-18 65.8 0.0 4.4e-18 65.8 0.0 4.3 3 1 1 4 4 4 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KRZ99820.1 - 3.2e-17 62.9 0.3 5.5e-15 55.6 0.0 3.4 3 1 0 3 3 3 1 DEAD/DEAH box helicase DUF4808 PF16066.5 KRZ99820.1 - 0.075 13.6 0.2 1.6 9.3 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4808) Pre-PUA PF17832.1 KRZ99821.1 - 1.2e-22 80.4 0.8 2e-22 79.7 0.8 1.3 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 KRZ99821.1 - 2.8e-19 68.8 0.0 4.6e-19 68.2 0.0 1.4 1 0 0 1 1 1 1 PUA domain DUF1947 PF09183.10 KRZ99821.1 - 0.0055 17.0 0.8 0.0055 17.0 0.8 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1947) CAP_GLY PF01302.25 KRZ99822.1 - 4e-13 49.2 0.1 8.2e-13 48.2 0.1 1.5 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.7 KRZ99822.1 - 2.4e-09 37.3 31.5 0.068 13.6 5.9 5.4 5 1 0 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KRZ99822.1 - 1.9e-07 30.7 29.4 0.00027 20.6 5.8 5.4 2 1 5 7 7 7 5 Leucine rich repeat LRR_1 PF00560.33 KRZ99822.1 - 3.8 8.4 16.8 12 7.0 0.1 6.8 5 1 0 5 5 5 0 Leucine Rich Repeat GN3L_Grn1 PF08701.11 KRZ99823.1 - 1.2e-22 79.8 13.6 4.1e-22 78.1 13.6 2.0 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 KRZ99823.1 - 4e-19 68.8 0.8 5e-15 55.6 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 KRZ99823.1 - 8.4e-11 41.6 0.3 2.8e-08 33.5 0.1 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KRZ99823.1 - 7.5e-09 35.7 0.7 1.1e-06 28.7 0.7 2.4 1 1 0 1 1 1 1 RsgA GTPase GTP_EFTU PF00009.27 KRZ99823.1 - 1.2e-05 25.0 0.3 0.011 15.3 0.0 2.7 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KRZ99823.1 - 0.00039 20.5 8.4 0.19 11.8 0.2 3.8 2 2 0 2 2 2 2 Dynamin family Roc PF08477.13 KRZ99823.1 - 0.0011 19.2 0.1 0.2 11.9 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 KRZ99823.1 - 0.012 15.2 0.2 0.55 9.8 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SRPRB PF09439.10 KRZ99823.1 - 0.015 14.7 0.0 0.044 13.2 0.0 1.8 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit MeaB PF03308.16 KRZ99823.1 - 0.019 13.9 0.9 0.043 12.8 0.0 2.0 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 KRZ99823.1 - 0.026 15.1 2.9 0.06 13.9 0.0 2.8 2 1 1 3 3 3 0 AAA domain TniB PF05621.11 KRZ99823.1 - 0.049 13.0 0.0 0.093 12.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein Ras PF00071.22 KRZ99823.1 - 0.083 12.5 0.0 1.2 8.7 0.0 2.3 2 0 0 2 2 2 0 Ras family Nuc_deoxyri_tr2 PF15891.5 KRZ99823.1 - 0.096 13.0 0.1 0.29 11.5 0.1 1.9 1 0 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase like AAA_16 PF13191.6 KRZ99823.1 - 0.11 12.9 2.4 1.2 9.5 0.0 3.0 1 1 1 2 2 2 0 AAA ATPase domain RRN3 PF05327.11 KRZ99823.1 - 2.6 6.5 6.0 3.5 6.0 6.0 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 GDA1_CD39 PF01150.17 KRZ99824.1 - 1.6e-123 412.5 0.5 2.4e-123 411.9 0.5 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family DUF5355 PF17306.2 KRZ99825.1 - 1.5e-97 326.6 21.7 1.5e-97 326.6 21.7 1.5 2 0 0 2 2 2 1 Family of unknown function (DUF5355) BRO1 PF03097.18 KRZ99825.1 - 5.2e-05 22.2 7.6 0.00068 18.5 3.0 2.5 1 1 1 2 2 2 2 BRO1-like domain RcbX PF02341.15 KRZ99825.1 - 0.028 14.7 0.1 0.097 12.9 0.1 1.9 1 0 0 1 1 1 0 RbcX protein Sec3_C PF09763.9 KRZ99826.1 - 2.7e-154 515.3 34.9 2.7e-154 515.3 34.9 1.8 2 0 0 2 2 2 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.6 KRZ99826.1 - 1.8e-16 60.0 0.7 1.2e-15 57.4 0.0 2.6 2 0 0 2 2 2 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Sec66 PF09802.9 KRZ99827.1 - 5.4e-70 234.6 1.6 7.3e-70 234.2 1.6 1.2 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 SieB PF14163.6 KRZ99827.1 - 0.01 15.3 0.7 0.23 11.0 0.1 2.8 3 0 0 3 3 3 0 Super-infection exclusion protein B HTH_12 PF08461.10 KRZ99827.1 - 0.13 12.2 0.2 1.8 8.6 0.0 2.4 2 0 0 2 2 2 0 Ribonuclease R winged-helix domain TRP PF06011.12 KRZ99827.1 - 0.13 11.0 0.1 0.13 11.0 0.1 1.4 2 0 0 2 2 2 0 Transient receptor potential (TRP) ion channel Folliculin PF11704.8 KRZ99827.1 - 7.2 6.4 10.0 30 4.4 5.0 2.6 2 1 1 3 3 3 0 Vesicle coat protein involved in Golgi to plasma membrane transport DUF3294 PF07957.11 KRZ99828.1 - 1.7e-76 256.7 8.2 2e-76 256.5 8.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3294) FAM92 PF06730.11 KRZ99828.1 - 0.039 13.4 5.1 0.88 8.9 1.3 2.2 2 0 0 2 2 2 0 FAM92 protein FAM76 PF16046.5 KRZ99828.1 - 6.4 6.0 6.1 6.8 6.0 4.9 1.6 1 1 1 2 2 2 0 FAM76 protein SlyX PF04102.12 KRZ99828.1 - 7.7 7.2 7.7 6.4 7.5 1.4 3.2 3 1 0 3 3 3 0 SlyX PGAP1 PF07819.13 KRZ99830.1 - 8.4e-96 320.1 0.0 1.2e-95 319.7 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_1 PF00561.20 KRZ99830.1 - 2.1e-05 24.3 0.3 0.00044 20.0 0.1 2.6 2 1 0 2 2 2 1 alpha/beta hydrolase fold Palm_thioest PF02089.15 KRZ99830.1 - 8.5e-05 22.5 0.0 0.00017 21.5 0.0 1.6 2 0 0 2 2 2 1 Palmitoyl protein thioesterase Hydrolase_4 PF12146.8 KRZ99830.1 - 0.00017 21.0 0.0 0.00064 19.1 0.0 1.9 3 0 0 3 3 3 1 Serine aminopeptidase, S33 DUF676 PF05057.14 KRZ99830.1 - 0.00047 19.7 0.0 0.00082 18.9 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 KRZ99830.1 - 0.00099 19.8 0.0 0.0014 19.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 KRZ99830.1 - 0.0031 17.3 0.0 0.0067 16.2 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.25 KRZ99830.1 - 0.029 14.2 0.0 0.065 13.1 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) Esterase PF00756.20 KRZ99830.1 - 0.063 12.9 0.0 0.099 12.3 0.0 1.3 1 0 0 1 1 1 0 Putative esterase HDV_ag PF01517.18 KRZ99831.1 - 0.059 13.2 9.1 0.087 12.6 9.1 1.3 1 0 0 1 1 1 0 Hepatitis delta virus delta antigen SOBP PF15279.6 KRZ99831.1 - 0.65 10.6 7.1 0.95 10.0 7.1 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Atg14 PF10186.9 KRZ99831.1 - 1.1 8.2 15.2 1.7 7.7 15.2 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF2011 PF09428.10 KRZ99832.1 - 2.9e-19 69.1 0.0 5e-19 68.3 0.0 1.4 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2011) COG5 PF10392.9 KRZ99833.1 - 1.4e-41 141.8 0.0 1.4e-41 141.8 0.0 2.6 2 1 1 3 3 3 1 Golgi transport complex subunit 5 Rb_C PF08934.10 KRZ99833.1 - 0.028 14.2 0.0 0.072 12.9 0.0 1.6 1 0 0 1 1 1 0 Rb C-terminal domain Sec23_trunk PF04811.15 KRZ99834.1 - 1.2e-65 221.5 0.0 1.7e-65 221.0 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 KRZ99834.1 - 1e-23 83.1 0.3 2.7e-23 81.8 0.3 1.8 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 KRZ99834.1 - 4.1e-18 65.9 0.1 1.1e-17 64.5 0.1 1.8 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 KRZ99834.1 - 3.8e-16 58.8 4.5 7.2e-16 58.0 4.5 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KRZ99834.1 - 0.012 15.4 0.0 0.04 13.8 0.0 1.9 1 0 0 1 1 1 0 Gelsolin repeat Vps36-NZF-N PF16988.5 KRZ99834.1 - 0.083 12.3 0.0 0.21 11.0 0.0 1.6 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Peptidase_S8 PF00082.22 KRZ99835.1 - 5.5e-30 104.7 4.0 2.6e-29 102.4 4.0 1.8 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KRZ99835.1 - 4.6e-07 30.4 0.1 9e-07 29.5 0.1 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 PUF PF00806.19 KRZ99836.1 - 0.17 11.6 0.3 11 6.0 0.0 3.3 3 0 0 3 3 3 0 Pumilio-family RNA binding repeat ACT_3 PF10000.9 KRZ99837.1 - 8.7e-26 89.6 0.1 1.3e-25 89.1 0.1 1.3 1 0 0 1 1 1 1 ACT domain ACT_7 PF13840.6 KRZ99837.1 - 1.2e-08 34.7 0.0 2.3e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 ACT domain Asn_synthase PF00733.21 KRZ99838.1 - 7.6e-21 75.2 0.5 9.7e-14 51.8 0.8 3.1 2 1 0 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 KRZ99838.1 - 4.6e-11 42.7 0.0 6e-10 39.1 0.0 2.6 2 1 0 2 2 2 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KRZ99838.1 - 3.6e-07 30.4 0.0 1e-06 29.0 0.0 1.7 1 1 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 KRZ99838.1 - 0.0096 15.4 0.0 0.024 14.1 0.0 1.6 1 0 0 1 1 1 1 Aluminium induced protein 4HBT PF03061.22 KRZ99839.1 - 8.5e-08 32.5 0.0 2.2e-07 31.2 0.0 1.6 2 0 0 2 2 2 1 Thioesterase superfamily DUF4336 PF14234.6 KRZ99840.1 - 1.5e-05 24.4 0.0 0.0019 17.5 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4336) DUF4336 PF14234.6 KRZ99841.1 - 0.038 13.2 0.0 2 7.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4336) Pkinase PF00069.25 KRZ99842.1 - 4e-24 85.4 0.3 9.8e-24 84.1 0.3 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KRZ99842.1 - 3e-10 39.8 0.0 5.8e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase ParcG PF10274.9 KRZ99842.1 - 0.022 14.9 0.5 0.022 14.9 0.5 3.2 2 1 0 3 3 3 0 Parkin co-regulated protein RRM_1 PF00076.22 KRZ99843.1 - 2.2e-11 43.4 0.0 3.4e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Metallophos PF00149.28 KRZ99844.1 - 4.5e-11 43.6 6.1 4.5e-11 43.6 6.1 2.9 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Gtr1_RagA PF04670.12 KRZ99845.1 - 5.2e-92 307.4 6.0 7e-92 307.0 6.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 KRZ99845.1 - 9.3e-08 32.3 0.0 3.1e-07 30.6 0.0 1.9 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KRZ99845.1 - 1.3e-07 31.4 0.2 2.7e-07 30.3 0.2 1.6 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 KRZ99845.1 - 6.6e-07 29.4 0.0 1.8e-06 28.0 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 KRZ99845.1 - 1.9e-06 27.4 4.8 2.1e-06 27.3 0.2 2.5 2 1 0 2 2 2 1 ADP-ribosylation factor family DUF815 PF05673.13 KRZ99845.1 - 0.015 14.5 0.0 0.028 13.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ABC_tran PF00005.27 KRZ99845.1 - 0.02 15.4 0.7 0.05 14.1 0.1 2.0 2 1 0 2 2 2 0 ABC transporter AAA_29 PF13555.6 KRZ99845.1 - 0.038 13.7 0.3 0.1 12.3 0.3 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KRZ99845.1 - 0.79 9.6 4.8 1.1 9.1 0.1 2.8 3 0 0 3 3 3 0 RsgA GTPase SQS_PSY PF00494.19 KRZ99846.1 - 4.8e-31 108.2 0.0 1.1e-21 77.6 0.0 2.1 1 1 1 2 2 2 2 Squalene/phytoene synthase MINDY_DUB PF04424.13 KRZ99847.1 - 1e-12 48.1 1.1 1.2e-11 44.6 0.7 2.7 1 1 1 2 2 2 1 MINDY deubiquitinase SirA PF10747.9 KRZ99847.1 - 0.67 10.3 5.5 1.7 9.0 0.8 2.6 2 0 0 2 2 2 0 Sporulation inhibitor of replication protein SirA Paf1 PF03985.13 KRZ99848.1 - 6.8e-96 321.8 23.9 7.7e-96 321.7 23.9 1.0 1 0 0 1 1 1 1 Paf1 FMN_red PF03358.15 KRZ99849.1 - 6e-12 45.6 0.0 8.9e-12 45.0 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 KRZ99849.1 - 4.5e-05 23.3 0.0 6.3e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_5 PF12724.7 KRZ99849.1 - 0.091 13.0 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 Flavodoxin domain Aldo_ket_red PF00248.21 KRZ99850.1 - 1.3e-26 93.5 0.1 2.9e-24 85.8 0.1 2.1 1 1 0 1 1 1 1 Aldo/keto reductase family EphA2_TM PF14575.6 KRZ99850.1 - 0.037 14.9 0.2 0.36 11.8 0.0 2.4 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Ras PF00071.22 KRZ99851.1 - 9.2e-52 174.9 0.3 1.1e-51 174.6 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KRZ99851.1 - 2.4e-35 121.4 0.2 3.6e-35 120.8 0.2 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KRZ99851.1 - 1.8e-15 56.8 0.1 2.2e-15 56.5 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KRZ99851.1 - 6.8e-08 32.1 0.3 8.4e-08 31.8 0.3 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KRZ99851.1 - 4.2e-07 30.0 0.0 6.7e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KRZ99851.1 - 2.7e-06 27.1 0.1 6.8e-05 22.5 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KRZ99851.1 - 2.3e-05 24.4 0.4 0.027 14.4 0.1 2.6 1 1 2 3 3 3 2 RsgA GTPase ATP_bind_1 PF03029.17 KRZ99851.1 - 4e-05 23.5 0.3 0.0031 17.3 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein SRPRB PF09439.10 KRZ99851.1 - 0.0002 20.9 0.2 0.00043 19.8 0.2 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 KRZ99851.1 - 0.00091 19.0 0.7 0.0046 16.7 0.7 2.2 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 KRZ99851.1 - 0.00098 19.4 0.1 0.01 16.1 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KRZ99851.1 - 0.0044 17.4 0.0 0.0075 16.7 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 KRZ99851.1 - 0.0049 16.8 0.0 0.01 15.8 0.0 1.5 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_5 PF07728.14 KRZ99851.1 - 0.0054 16.7 0.5 0.1 12.6 0.5 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) NACHT PF05729.12 KRZ99851.1 - 0.0058 16.6 0.0 0.0088 16.0 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_24 PF13479.6 KRZ99851.1 - 0.0078 16.0 0.1 0.028 14.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain Septin PF00735.18 KRZ99851.1 - 0.01 15.1 1.0 0.017 14.4 0.2 1.7 2 1 1 3 3 3 0 Septin AAA_7 PF12775.7 KRZ99851.1 - 0.015 14.8 0.1 0.024 14.2 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region NB-ARC PF00931.22 KRZ99851.1 - 0.023 13.9 0.0 0.033 13.4 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_14 PF13173.6 KRZ99851.1 - 0.029 14.4 0.4 0.14 12.2 0.1 2.1 2 1 0 2 2 2 0 AAA domain TniB PF05621.11 KRZ99851.1 - 0.037 13.5 0.0 0.058 12.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein G-alpha PF00503.20 KRZ99851.1 - 0.042 13.0 3.1 0.14 11.3 3.1 2.0 1 1 0 1 1 1 0 G-protein alpha subunit cobW PF02492.19 KRZ99851.1 - 0.045 13.3 0.6 0.17 11.5 0.1 1.9 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MCM PF00493.23 KRZ99851.1 - 0.07 12.2 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain NTPase_1 PF03266.15 KRZ99851.1 - 0.074 13.0 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 NTPase RNA_helicase PF00910.22 KRZ99851.1 - 0.087 13.2 0.1 0.23 11.8 0.0 1.8 2 0 0 2 2 2 0 RNA helicase PRK PF00485.18 KRZ99851.1 - 0.1 12.3 0.3 0.33 10.7 0.0 1.8 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family ABC_tran PF00005.27 KRZ99851.1 - 0.15 12.6 1.2 0.23 12.0 1.2 1.7 1 1 0 1 1 1 0 ABC transporter DUF1771 PF08590.10 KRZ99852.1 - 8.2e-19 67.7 12.9 8.2e-19 67.7 12.9 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.21 KRZ99852.1 - 5.3e-11 42.7 0.2 1.2e-10 41.5 0.0 1.7 2 0 0 2 2 2 1 Smr domain Seryl_tRNA_N PF02403.22 KRZ99852.1 - 0.00054 20.2 1.5 0.00054 20.2 1.5 1.7 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain Peptidase_M3_N PF08439.10 KRZ99852.1 - 0.067 13.5 1.5 0.17 12.1 1.5 1.7 1 1 0 1 1 1 0 Oligopeptidase F DUF2203 PF09969.9 KRZ99852.1 - 8.8 7.1 7.8 3 8.6 4.0 2.2 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) SRP54 PF00448.22 KRZ99853.1 - 9.5e-48 162.4 0.7 2.8e-47 160.9 0.7 1.8 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.13 KRZ99853.1 - 3.5e-06 27.2 3.8 5.1e-06 26.6 3.8 1.2 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal MeaB PF03308.16 KRZ99853.1 - 1.6e-05 24.1 0.0 4.5e-05 22.6 0.0 1.8 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB SRP54_N PF02881.19 KRZ99853.1 - 0.00022 21.4 1.0 0.00078 19.6 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain AAA_22 PF13401.6 KRZ99853.1 - 0.00069 19.9 0.1 0.0064 16.8 0.0 2.7 2 2 0 2 2 2 1 AAA domain AAA_31 PF13614.6 KRZ99853.1 - 0.0015 18.5 0.3 0.057 13.3 0.0 2.7 1 1 1 2 2 2 1 AAA domain ArsA_ATPase PF02374.15 KRZ99853.1 - 0.0019 17.5 0.0 0.77 8.9 0.0 2.7 1 1 1 2 2 2 2 Anion-transporting ATPase AAA_24 PF13479.6 KRZ99853.1 - 0.0027 17.5 0.2 0.014 15.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 KRZ99853.1 - 0.0038 17.3 0.0 0.015 15.4 0.0 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_30 PF13604.6 KRZ99853.1 - 0.0079 15.9 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 KRZ99853.1 - 0.017 15.5 0.2 0.16 12.4 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.6 KRZ99853.1 - 0.022 14.8 0.3 0.54 10.3 0.0 2.9 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.12 KRZ99853.1 - 0.035 13.4 0.0 0.43 9.8 0.0 2.4 1 1 0 1 1 1 0 Zeta toxin DUF507 PF04368.13 KRZ99853.1 - 0.069 13.1 4.0 2.4 8.1 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF507) AAA_16 PF13191.6 KRZ99853.1 - 0.09 13.1 0.0 0.26 11.7 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain End3 PF12761.7 KRZ99853.1 - 5.6 7.1 12.1 0.75 9.9 2.6 2.6 1 1 1 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 PS_Dcarbxylase PF02666.15 KRZ99854.1 - 3.2e-58 196.6 0.1 4.9e-58 196.0 0.1 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 KRZ99854.1 - 9.7e-26 90.1 1.3 4e-14 52.8 0.0 2.9 2 0 0 2 2 2 2 C2 domain PI3K_C2 PF00792.24 KRZ99854.1 - 0.0033 17.3 1.8 0.02 14.8 0.4 2.4 2 0 0 2 2 2 1 Phosphoinositide 3-kinase C2 CEP76-C2 PF15627.6 KRZ99854.1 - 0.086 12.4 0.3 1.1 8.8 0.1 2.4 2 0 0 2 2 2 0 CEP76 C2 domain MMtag PF10159.9 KRZ99854.1 - 0.15 12.3 0.8 0.48 10.7 0.8 1.8 1 0 0 1 1 1 0 Multiple myeloma tumor-associated Rbsn PF11464.8 KRZ99855.1 - 0.059 13.1 0.2 0.11 12.3 0.0 1.5 2 0 0 2 2 2 0 Rabenosyn Rab binding domain tRNA-synt_1g PF09334.11 KRZ99856.1 - 2.1e-156 520.6 4.4 2.7e-156 520.2 4.4 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KRZ99856.1 - 9e-10 37.4 1.4 0.00014 20.2 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) MetRS-N PF09635.10 KRZ99856.1 - 5.3e-08 33.4 2.1 1.5e-07 32.0 2.1 1.9 1 0 0 1 1 1 1 MetRS-N binding domain Anticodon_1 PF08264.13 KRZ99856.1 - 0.013 15.5 0.0 0.046 13.7 0.0 2.0 2 0 0 2 2 2 0 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 KRZ99856.1 - 0.037 13.4 0.2 0.18 11.1 0.2 2.0 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain BDV_P24 PF06595.11 KRZ99856.1 - 0.2 11.5 0.1 0.36 10.7 0.1 1.3 1 0 0 1 1 1 0 Borna disease virus P24 protein Amidase PF01425.21 KRZ99857.1 - 2.9e-109 366.0 0.0 3.4e-109 365.8 0.0 1.0 1 0 0 1 1 1 1 Amidase DUF4469 PF14734.6 KRZ99857.1 - 0.13 12.4 0.1 2.2 8.5 0.1 2.6 3 1 0 3 3 3 0 Domain of unknown function (DUF4469) with IG-like fold GTP_cyclohydroI PF01227.22 KRZ99858.1 - 4.8e-77 257.4 0.3 5.9e-77 257.1 0.3 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 KRZ99858.1 - 0.00025 21.1 0.0 0.00091 19.3 0.0 1.9 2 0 0 2 2 2 1 QueF-like protein RNB PF00773.19 KRZ99859.1 - 9.7e-66 222.3 3.5 2.1e-65 221.2 3.5 1.5 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 KRZ99859.1 - 1.8e-23 82.3 0.1 4.7e-23 81.0 0.1 1.8 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Dis3l2_C_term PF17877.1 KRZ99859.1 - 5.3e-23 81.2 0.0 1.6e-22 79.6 0.0 1.9 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal CSD2 PF17876.1 KRZ99859.1 - 2.7e-06 27.5 0.0 0.00021 21.4 0.0 2.9 2 0 0 2 2 2 1 Cold shock domain OB_RNB PF08206.11 KRZ99859.1 - 0.0094 15.6 0.0 5.7 6.7 0.0 2.7 2 0 0 2 2 2 2 Ribonuclease B OB domain Rrp44_CSD1 PF17216.3 KRZ99859.1 - 0.014 15.1 0.0 0.048 13.4 0.0 2.0 2 0 0 2 2 2 0 Rrp44-like cold shock domain Rrp44_S1 PF17215.3 KRZ99859.1 - 0.035 14.1 0.0 0.09 12.7 0.0 1.6 1 0 0 1 1 1 0 S1 domain DNA_pol_E_B PF04042.16 KRZ99860.1 - 1.4e-38 132.4 0.1 2.6e-38 131.5 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 KRZ99860.1 - 7.1e-29 100.5 0.0 3.2e-28 98.4 0.0 1.9 2 0 0 2 2 2 1 DNA polymerase delta subunit OB-fold domain DEAD PF00270.29 KRZ99861.1 - 2.3e-47 161.0 0.9 5.2e-47 159.9 0.0 2.0 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KRZ99861.1 - 1.2e-24 86.8 0.0 7.5e-24 84.2 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KRZ99861.1 - 4.1e-17 62.2 0.1 7.5e-17 61.3 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) AAA_22 PF13401.6 KRZ99861.1 - 0.18 12.1 2.5 0.34 11.2 0.0 2.7 4 0 0 4 4 4 0 AAA domain Merozoite_SPAM PF07133.11 KRZ99861.1 - 0.67 9.9 22.0 1.2 9.1 22.0 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Sec63 PF02889.16 KRZ99862.1 - 1.2e-127 424.4 0.8 1.2e-82 276.9 0.1 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 KRZ99862.1 - 3.4e-51 173.5 1.6 3.1e-25 88.9 0.6 3.8 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.15 KRZ99862.1 - 1.1e-26 93.9 0.0 1.2e-14 54.6 0.0 2.7 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KRZ99862.1 - 7.7e-18 64.9 0.1 1.4e-07 31.8 0.0 3.7 2 2 0 2 2 2 2 Helicase conserved C-terminal domain AAA_19 PF13245.6 KRZ99862.1 - 8.2e-06 26.2 0.4 0.032 14.6 0.4 2.8 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KRZ99862.1 - 8.2e-06 26.1 3.4 0.18 12.1 0.4 4.0 3 2 0 3 3 2 2 AAA domain AAA PF00004.29 KRZ99862.1 - 0.00013 22.4 1.3 0.14 12.6 0.0 3.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Helicase_PWI PF18149.1 KRZ99862.1 - 0.00014 22.0 0.1 0.00055 20.1 0.1 2.0 1 0 0 1 1 1 1 N-terminal helicase PWI domain PhoH PF02562.16 KRZ99862.1 - 0.0012 18.4 0.0 0.18 11.2 0.0 2.6 2 0 0 2 2 2 1 PhoH-like protein IstB_IS21 PF01695.17 KRZ99862.1 - 0.0071 16.1 0.3 5.1 6.8 0.0 4.0 5 0 0 5 5 5 1 IstB-like ATP binding protein T2SSE PF00437.20 KRZ99862.1 - 0.02 13.9 0.0 4.4 6.3 0.0 2.9 3 0 0 3 3 3 0 Type II/IV secretion system protein TniB PF05621.11 KRZ99862.1 - 0.14 11.6 1.6 15 4.9 0.1 3.4 3 0 0 3 3 3 0 Bacterial TniB protein Efg1 PF10153.9 KRZ99863.1 - 2.9e-33 114.6 12.1 2.9e-33 114.6 12.1 2.3 2 1 0 2 2 2 1 rRNA-processing protein Efg1 CoA_binding_3 PF13727.6 KRZ99863.1 - 0.016 15.2 1.0 0.029 14.4 0.7 1.5 1 1 0 1 1 1 0 CoA-binding domain MMR_HSR1_Xtn PF16897.5 KRZ99864.1 - 1.4e-37 127.9 1.4 6.4e-37 125.8 0.9 2.1 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 KRZ99864.1 - 5.2e-20 71.6 0.1 1.1e-19 70.6 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 KRZ99864.1 - 5.4e-20 71.2 0.0 1.2e-19 70.1 0.0 1.6 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 KRZ99864.1 - 5.3e-13 48.8 0.1 8.9e-13 48.1 0.1 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KRZ99864.1 - 0.004 17.2 1.0 0.12 12.4 0.0 2.4 1 1 1 2 2 2 1 Dynamin family YchF-GTPase_C PF06071.13 KRZ99864.1 - 0.12 12.6 0.5 0.47 10.7 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF933) Roc PF08477.13 KRZ99864.1 - 0.13 12.5 0.2 1.1 9.5 0.0 2.3 1 1 1 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Dynamitin PF04912.14 KRZ99865.1 - 2.3e-38 132.6 18.0 1e-37 130.5 18.0 2.0 1 1 0 1 1 1 1 Dynamitin DUF4200 PF13863.6 KRZ99865.1 - 0.072 13.5 8.1 4.6 7.7 0.2 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) RasGAP_C PF03836.15 KRZ99865.1 - 0.13 12.4 12.9 2.5 8.2 0.8 3.7 3 1 0 3 3 3 0 RasGAP C-terminus Spc7 PF08317.11 KRZ99865.1 - 0.34 9.7 17.2 0.097 11.5 3.7 3.0 1 1 2 3 3 3 0 Spc7 kinetochore protein DUF4191 PF13829.6 KRZ99865.1 - 1 8.7 3.3 4.8 6.4 0.2 2.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4191) SlyX PF04102.12 KRZ99865.1 - 1 10.0 12.9 1.5 9.5 0.4 5.2 5 2 1 6 6 5 0 SlyX DivIC PF04977.15 KRZ99865.1 - 1.8 8.4 7.4 1.6 8.6 0.4 3.6 3 0 0 3 3 3 0 Septum formation initiator NPV_P10 PF05531.12 KRZ99865.1 - 2.4 8.7 23.2 3.3 8.2 2.1 5.3 3 2 1 5 5 5 0 Nucleopolyhedrovirus P10 protein TolA_bind_tri PF16331.5 KRZ99865.1 - 2.6 8.2 12.7 4.2 7.5 0.3 4.2 4 1 0 4 4 4 0 TolA binding protein trimerisation DUF16 PF01519.16 KRZ99865.1 - 2.7 8.5 17.8 1.6 9.3 0.3 4.5 3 2 2 5 5 5 0 Protein of unknown function DUF16 DUF724 PF05266.14 KRZ99865.1 - 3 7.6 10.2 0.29 10.9 0.3 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF724) DHR10 PF18595.1 KRZ99865.1 - 4 7.5 8.0 14 5.7 0.3 3.2 3 0 0 3 3 3 0 Designed helical repeat protein 10 domain SesA PF17107.5 KRZ99865.1 - 7.1 6.8 9.8 0.93 9.7 0.1 3.5 3 2 1 4 4 4 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF4665 PF15679.5 KRZ99865.1 - 8 7.2 14.1 2.6 8.7 0.2 4.0 3 2 2 5 5 5 0 Domain of unknown function (DUF4665) Exonuc_VII_L PF02601.15 KRZ99865.1 - 9.9 5.6 11.1 2.4e+02 1.1 11.1 2.4 1 1 0 1 1 1 0 Exonuclease VII, large subunit Aldedh PF00171.22 KRZ99866.1 - 9.1e-108 360.7 0.0 1.1e-107 360.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DnaJ_CXXCXGXG PF00684.19 KRZ99867.1 - 3.6e-06 27.3 16.8 0.045 14.1 12.5 3.0 2 1 1 3 3 3 3 DnaJ central domain DUF2318 PF10080.9 KRZ99867.1 - 0.19 11.9 10.6 2.3 8.4 1.6 2.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2318) HypA PF01155.19 KRZ99867.1 - 0.3 11.1 7.4 2.3 8.3 3.3 3.0 2 1 1 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA ADD_DNMT3 PF17980.1 KRZ99867.1 - 0.88 9.6 9.9 30 4.7 0.0 4.4 5 0 0 5 5 5 0 Cysteine rich ADD domain in DNMT3 cEGF PF12662.7 KRZ99867.1 - 0.89 9.6 13.8 1.2 9.2 3.4 2.7 2 0 0 2 2 2 0 Complement Clr-like EGF-like TackOD1 PF18551.1 KRZ99867.1 - 1.6 8.3 7.7 3 7.5 0.3 2.8 3 0 0 3 3 3 0 Thaumarchaeal output domain 1 zinc-ribbons_6 PF07191.12 KRZ99867.1 - 2 8.5 12.3 7 6.7 0.7 3.0 2 1 1 3 3 3 0 zinc-ribbons Gin PF10764.9 KRZ99867.1 - 3.9 7.5 12.2 0.52 10.3 0.8 2.7 3 0 0 3 3 3 0 Inhibitor of sigma-G Gin Got1 PF04178.12 KRZ99868.1 - 5e-13 49.5 9.3 6.4e-13 49.1 9.3 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family DUF973 PF06157.11 KRZ99868.1 - 0.056 12.5 3.1 0.081 12.0 3.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF973) DUF3098 PF11297.8 KRZ99868.1 - 0.11 12.1 3.8 1.4 8.6 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3098) Oxidored_q2 PF00420.24 KRZ99868.1 - 2.7 7.6 6.9 5.7 6.6 0.7 2.2 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L ApbA_C PF08546.11 KRZ99871.1 - 5.5e-37 126.8 0.1 8.6e-37 126.1 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 KRZ99871.1 - 2e-32 112.0 0.0 2.8e-32 111.5 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 KRZ99871.1 - 0.033 14.2 0.0 0.076 13.1 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF2368 PF10166.9 KRZ99871.1 - 0.08 12.6 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2368) Abhydrolase_1 PF00561.20 KRZ99871.1 - 0.13 11.9 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold CoaE PF01121.20 KRZ99872.1 - 5.9e-60 202.0 0.1 7.1e-60 201.7 0.1 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 KRZ99872.1 - 9.6e-08 32.6 0.2 3.3e-07 30.9 0.1 1.9 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 KRZ99872.1 - 0.00012 22.2 0.3 0.0012 19.0 0.3 2.4 1 1 0 1 1 1 1 AAA domain SKI PF01202.22 KRZ99872.1 - 0.00042 20.5 0.2 0.13 12.4 0.0 2.2 2 0 0 2 2 2 2 Shikimate kinase AAA_17 PF13207.6 KRZ99872.1 - 0.001 19.5 0.0 0.023 15.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain Cytidylate_kin2 PF13189.6 KRZ99872.1 - 0.0023 18.1 0.9 1.9 8.6 0.2 2.3 2 0 0 2 2 2 2 Cytidylate kinase-like family PRK PF00485.18 KRZ99872.1 - 0.0028 17.4 0.3 0.025 14.3 0.0 2.1 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_22 PF13401.6 KRZ99872.1 - 0.0031 17.8 0.1 0.31 11.3 0.0 2.4 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 KRZ99872.1 - 0.0059 15.9 0.1 0.18 11.1 0.0 2.1 2 0 0 2 2 2 1 Zeta toxin AAA_28 PF13521.6 KRZ99872.1 - 0.013 15.7 0.0 0.054 13.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 KRZ99872.1 - 0.08 12.8 0.1 1.3 8.9 0.0 2.1 2 0 0 2 2 2 0 Adenylylsulphate kinase CLP1_P PF16575.5 KRZ99872.1 - 0.08 12.7 0.0 11 5.7 0.0 2.2 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop PI3_PI4_kinase PF00454.27 KRZ99873.1 - 7.4e-46 157.0 0.0 2e-45 155.6 0.0 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 KRZ99873.1 - 2.4e-33 115.1 5.9 6.8e-21 74.5 0.9 2.8 2 1 0 2 2 2 2 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_C2 PF00792.24 KRZ99873.1 - 6.1e-23 81.3 0.1 1.4e-22 80.1 0.1 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 His_Phos_1 PF00300.22 KRZ99874.1 - 0.0096 15.6 0.0 1.6 8.3 0.0 2.5 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) DUF916 PF06030.12 KRZ99874.1 - 0.27 11.3 2.6 0.77 9.8 2.6 1.8 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF916) Cation_efflux PF01545.21 KRZ99875.1 - 2e-38 132.1 11.8 2e-38 132.1 11.8 3.0 2 1 0 2 2 2 1 Cation efflux family ATP_bind_1 PF03029.17 KRZ99876.1 - 1e-86 290.7 0.0 1.2e-86 290.5 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein MeaB PF03308.16 KRZ99876.1 - 0.00057 19.0 0.1 0.0017 17.4 0.0 1.7 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB CLP1_P PF16575.5 KRZ99876.1 - 0.0017 18.2 0.0 0.0044 16.8 0.0 1.7 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop RsgA_GTPase PF03193.16 KRZ99876.1 - 0.0038 17.1 0.4 0.071 13.0 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase RNA_helicase PF00910.22 KRZ99876.1 - 0.007 16.7 0.0 0.032 14.6 0.0 2.1 2 0 0 2 2 2 1 RNA helicase CbiA PF01656.23 KRZ99876.1 - 0.013 15.6 0.0 0.018 15.1 0.0 1.2 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain MMR_HSR1 PF01926.23 KRZ99876.1 - 0.019 15.1 0.0 0.082 13.0 0.0 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase KAP_NTPase PF07693.14 KRZ99876.1 - 0.041 13.1 0.0 0.058 12.6 0.0 1.6 1 1 0 1 1 1 0 KAP family P-loop domain AAA_31 PF13614.6 KRZ99876.1 - 0.047 13.6 0.0 1.7 8.5 0.0 2.4 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KRZ99876.1 - 0.053 13.0 0.0 0.15 11.5 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF87 PF01935.17 KRZ99876.1 - 0.055 13.6 0.0 0.18 11.9 0.0 1.8 2 0 0 2 2 2 0 Helicase HerA, central domain AAA PF00004.29 KRZ99876.1 - 0.068 13.6 0.0 0.15 12.5 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ArsA_ATPase PF02374.15 KRZ99876.1 - 0.074 12.2 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Anion-transporting ATPase AAA_10 PF12846.7 KRZ99876.1 - 0.086 11.7 0.0 0.16 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_18 PF13238.6 KRZ99876.1 - 0.091 13.3 0.0 0.23 12.0 0.0 1.8 1 1 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 KRZ99876.1 - 0.096 12.2 0.0 1.7 8.1 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 KRZ99876.1 - 0.13 12.8 0.0 0.33 11.5 0.0 1.7 2 0 0 2 2 2 0 ABC transporter AAA_24 PF13479.6 KRZ99876.1 - 0.13 11.9 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KRZ99876.1 - 0.18 11.8 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 KRZ99876.1 - 0.28 10.9 0.0 0.6 9.8 0.0 1.4 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.13 KRZ99877.1 - 7.3e-169 561.5 0.9 2.6e-168 559.7 0.1 1.8 2 0 0 2 2 2 1 TIP49 P-loop domain TIP49_C PF17856.1 KRZ99877.1 - 3.5e-20 71.9 0.0 9.4e-20 70.5 0.0 1.8 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 KRZ99877.1 - 2.9e-10 40.7 0.1 3.9e-07 30.6 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KRZ99877.1 - 5.4e-09 36.0 0.3 9.1e-07 28.8 0.0 2.7 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KRZ99877.1 - 8.6e-05 22.8 0.1 0.2 11.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 KRZ99877.1 - 0.00017 21.6 0.1 0.1 12.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KRZ99877.1 - 0.00046 20.6 0.2 0.0028 18.0 0.1 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 KRZ99877.1 - 0.0017 17.9 0.1 0.0043 16.6 0.1 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KRZ99877.1 - 0.0018 17.6 0.1 0.0034 16.7 0.1 1.4 1 0 0 1 1 1 1 Zeta toxin Sigma54_activat PF00158.26 KRZ99877.1 - 0.0027 17.4 0.0 0.9 9.2 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 KRZ99877.1 - 0.0037 16.7 0.1 0.19 11.1 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 KRZ99877.1 - 0.0041 17.4 0.0 0.008 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KRZ99877.1 - 0.0068 17.0 0.1 0.031 14.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KRZ99877.1 - 0.008 16.5 1.8 0.23 11.8 1.8 2.4 1 1 0 1 1 1 1 AAA domain DnaB_C PF03796.15 KRZ99877.1 - 0.0084 15.5 0.0 0.022 14.1 0.0 1.7 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_14 PF13173.6 KRZ99877.1 - 0.014 15.5 0.0 2.8 8.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KRZ99877.1 - 0.03 14.1 0.1 0.064 13.0 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 KRZ99877.1 - 0.032 13.8 0.1 0.52 9.8 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF2075 PF09848.9 KRZ99877.1 - 0.069 12.4 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PIF1 PF05970.14 KRZ99877.1 - 0.075 12.2 0.0 4.2 6.4 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase ATPase PF06745.13 KRZ99877.1 - 0.098 12.0 0.2 0.28 10.5 0.0 1.7 2 0 0 2 2 2 0 KaiC AAA_17 PF13207.6 KRZ99877.1 - 0.11 12.9 0.1 0.57 10.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KRZ99877.1 - 0.11 12.2 0.1 3.5 7.3 0.1 2.4 2 0 0 2 2 2 0 AAA domain Sec1 PF00995.23 KRZ99878.1 - 1.4e-113 381.2 16.3 1.6e-113 381.0 16.3 1.0 1 0 0 1 1 1 1 Sec1 family Zn_clus PF00172.18 KRZ99879.1 - 3.9e-07 30.1 10.3 6.4e-07 29.4 10.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Clusterin PF01093.17 KRZ99879.1 - 0.076 12.1 2.7 0.09 11.8 2.7 1.1 1 0 0 1 1 1 0 Clusterin Cpn60_TCP1 PF00118.24 KRZ99880.1 - 6.8e-166 552.7 0.6 7.8e-166 552.5 0.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Translin PF01997.16 KRZ99881.1 - 5e-36 124.6 1.3 6.8e-36 124.2 1.3 1.2 1 0 0 1 1 1 1 Translin family Peptidase_M24 PF00557.24 KRZ99882.1 - 1.3e-48 165.5 0.0 1.6e-48 165.2 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 KRZ99882.1 - 3.4e-18 65.7 7.1 9.8e-18 64.2 7.1 1.8 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 KRZ99882.1 - 0.0072 16.4 3.8 0.0072 16.4 3.8 2.2 2 0 0 2 2 2 1 MYND finger LmjF365940-deam PF14421.6 KRZ99883.1 - 0.00035 20.2 0.0 0.0004 20.1 0.0 1.1 1 0 0 1 1 1 1 A distinct subfamily of CDD/CDA-like deaminases dCMP_cyt_deam_1 PF00383.23 KRZ99883.1 - 0.11 12.4 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Cytidine and deoxycytidylate deaminase zinc-binding region AAA PF00004.29 KRZ99884.1 - 6.8e-41 139.8 0.0 1.4e-40 138.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KRZ99884.1 - 8.9e-18 64.0 0.1 1.9e-17 63.0 0.1 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 KRZ99884.1 - 2.7e-08 33.5 0.0 6.9e-08 32.2 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 KRZ99884.1 - 9.2e-05 22.6 0.0 0.00026 21.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KRZ99884.1 - 9.5e-05 22.8 3.0 0.021 15.2 0.0 2.7 2 1 1 3 3 3 2 AAA ATPase domain RuvB_N PF05496.12 KRZ99884.1 - 0.00075 19.3 0.1 0.0017 18.1 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KRZ99884.1 - 0.00097 19.1 0.2 0.0066 16.5 0.2 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KRZ99884.1 - 0.002 18.4 2.1 0.16 12.3 0.0 3.4 3 1 1 4 4 4 1 AAA domain AAA_33 PF13671.6 KRZ99884.1 - 0.0038 17.4 0.0 0.011 16.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 KRZ99884.1 - 0.018 14.2 0.0 0.047 12.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 KRZ99884.1 - 0.019 14.4 0.1 0.051 13.0 0.1 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI PhoH PF02562.16 KRZ99884.1 - 0.02 14.3 0.1 0.073 12.5 0.1 1.9 2 0 0 2 2 2 0 PhoH-like protein IstB_IS21 PF01695.17 KRZ99884.1 - 0.046 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_11 PF13086.6 KRZ99884.1 - 0.32 10.8 3.8 0.71 9.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain MAP65_ASE1 PF03999.12 KRZ99884.1 - 0.33 9.6 6.8 0.48 9.1 6.8 1.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) DSS1_SEM1 PF05160.13 KRZ99885.1 - 2.2e-20 72.5 18.5 2.9e-20 72.1 18.5 1.2 1 0 0 1 1 1 1 DSS1/SEM1 family RNA_pol_Rpb1_1 PF04997.12 KRZ99886.1 - 1e-85 287.8 0.0 1.6e-85 287.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 KRZ99886.1 - 2e-83 279.9 0.3 3.6e-83 279.1 0.1 1.5 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KRZ99886.1 - 1.6e-74 249.7 0.0 2.7e-74 248.9 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 KRZ99886.1 - 8.1e-40 136.3 0.0 4.8e-39 133.8 0.0 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 KRZ99886.1 - 3e-31 107.5 0.0 1.3e-30 105.6 0.0 2.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Apc13p PF05839.11 KRZ99887.1 - 9.1e-07 29.0 0.2 2.3e-06 27.7 0.2 1.7 1 1 0 1 1 1 1 Apc13p protein Cnn_1N PF07989.11 KRZ99888.1 - 2.6e-10 40.3 9.9 2.6e-10 40.3 9.9 12.6 2 2 10 12 12 12 3 Centrosomin N-terminal motif 1 TMF_TATA_bd PF12325.8 KRZ99888.1 - 0.00054 20.2 8.0 0.00054 20.2 8.0 11.6 3 2 9 13 13 13 1 TATA element modulatory factor 1 TATA binding KorB PF08535.10 KRZ99888.1 - 0.0063 16.5 0.9 2.2 8.4 0.1 3.1 2 0 0 2 2 2 2 KorB domain UPF0242 PF06785.11 KRZ99888.1 - 0.008 16.3 14.1 0.008 16.3 14.1 9.2 1 1 6 7 7 7 2 Uncharacterised protein family (UPF0242) N-terminus CENP-F_leu_zip PF10473.9 KRZ99888.1 - 0.011 15.7 12.8 0.011 15.7 12.8 8.7 1 1 7 9 9 9 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.11 KRZ99888.1 - 0.16 12.2 121.1 0.041 14.1 24.5 7.9 1 1 5 7 7 7 0 Autophagy protein 16 (ATG16) Cytochrom_NNT PF03264.14 KRZ99888.1 - 0.92 9.2 4.1 6.1 6.5 4.1 2.5 1 0 0 1 1 1 0 NapC/NirT cytochrome c family, N-terminal region Spc110_C PF18520.1 KRZ99888.1 - 1.1 8.9 7.3 0.24 11.0 1.3 3.2 2 0 0 2 2 2 0 Spindle pole body component 110 C-terminal domain Glycos_transf_3 PF00591.21 KRZ99889.1 - 4.4e-81 272.2 0.0 5.1e-81 272.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glyco_hydro_31 PF01055.26 KRZ99890.1 - 3.8e-45 154.9 0.5 5.4e-45 154.4 0.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KRZ99890.1 - 5.4e-19 68.3 0.3 1.5e-18 66.9 0.3 1.8 1 0 0 1 1 1 1 Galactose mutarotase-like Glyco_hydro_31 PF01055.26 KRZ99891.1 - 6.2e-52 177.2 0.0 8e-52 176.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Zip PF02535.22 KRZ99892.1 - 3.9e-35 121.7 23.1 3.9e-35 121.7 23.1 2.5 2 1 0 2 2 2 1 ZIP Zinc transporter Plasmodium_Vir PF05795.11 KRZ99892.1 - 0.42 10.0 4.0 0.22 10.9 0.1 2.0 2 0 0 2 2 2 0 Plasmodium vivax Vir protein HRXXH PF13933.6 KRZ99893.1 - 1.4e-109 365.4 2.6 1.8e-109 365.0 2.6 1.1 1 0 0 1 1 1 1 Putative peptidase family Aspzincin_M35 PF14521.6 KRZ99893.1 - 2.9e-07 31.1 0.4 6.4e-07 30.0 0.4 1.6 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase Catalase PF00199.19 KRZ99894.1 - 3.3e-171 569.6 0.0 4.2e-171 569.3 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 KRZ99894.1 - 7.2e-12 45.3 0.0 1.7e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive Mito_carr PF00153.27 KRZ99895.1 - 1.2e-37 127.7 10.4 1.6e-14 53.6 0.1 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein Alpha-L-AF_C PF06964.12 KRZ99896.1 - 2.6e-30 105.8 0.0 3.8e-30 105.2 0.0 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain Glyco_hydro_44 PF12891.7 KRZ99896.1 - 0.049 13.6 0.2 0.12 12.3 0.2 1.6 1 1 0 1 1 1 0 Glycoside hydrolase family 44 Sugar_tr PF00083.24 KRZ99897.1 - 5.1e-95 319.0 25.3 5.8e-95 318.8 25.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KRZ99897.1 - 1.1e-26 93.6 25.8 1.1e-26 93.6 25.8 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily DpnI_C PF17726.1 KRZ99898.1 - 0.032 14.4 0.1 0.094 12.9 0.1 1.8 1 0 0 1 1 1 0 Dam-replacing HTH domain DASH_Spc34 PF08657.10 KRZ99898.1 - 0.055 13.3 0.3 0.082 12.7 0.3 1.2 1 0 0 1 1 1 0 DASH complex subunit Spc34 Thiolase_N PF00108.23 KRZ99899.1 - 9.9e-79 264.3 0.2 1.5e-78 263.8 0.2 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KRZ99899.1 - 3.2e-43 146.3 0.8 3.2e-43 146.3 0.8 1.6 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KRZ99899.1 - 0.00035 20.2 0.9 0.0015 18.2 0.5 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KRZ99899.1 - 0.022 14.6 0.4 7.9 6.4 0.3 2.6 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Pyrid_oxidase_2 PF13883.6 KRZ99901.1 - 1e-53 181.8 0.0 1.3e-53 181.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Imm1 PF14430.6 KRZ99901.1 - 0.11 13.2 0.1 0.19 12.4 0.1 1.4 1 0 0 1 1 1 0 Immunity protein Imm1 Methyltransf_2 PF00891.18 KRZ99902.1 - 6.6e-34 117.0 0.0 9.5e-34 116.5 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 KRZ99902.1 - 3.3e-08 33.4 0.0 6.9e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Dimerisation domain TrmB PF01978.19 KRZ99902.1 - 8.8e-05 22.3 0.1 0.00023 21.0 0.1 1.6 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB AAA_assoc_C PF09821.9 KRZ99902.1 - 0.094 13.3 0.0 0.21 12.1 0.0 1.5 1 0 0 1 1 1 0 C-terminal AAA-associated domain OPT PF03169.15 KRZ99903.1 - 2e-167 558.5 38.8 2.3e-167 558.3 38.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4064 PF13273.6 KRZ99903.1 - 1.6 9.1 8.6 0.83 10.0 0.1 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF4064) MFS_1 PF07690.16 KRZ99904.1 - 3.2e-12 46.1 59.0 1.7e-09 37.1 58.9 3.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KRZ99904.1 - 0.0024 16.4 32.7 0.0064 15.0 32.7 1.7 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3430 PF11912.8 KRZ99905.1 - 0.00078 19.5 1.3 0.00083 19.5 1.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) MFS_1 PF07690.16 KRZ99906.1 - 2.5e-07 30.0 12.6 2e-06 27.0 12.6 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 KRZ99906.1 - 0.0072 14.7 1.2 0.011 14.1 1.2 1.3 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.13 KRZ99906.1 - 0.17 10.2 4.5 0.23 9.8 4.5 1.1 1 0 0 1 1 1 0 Transmembrane secretion effector Sigma_reg_N PF13800.6 KRZ99906.1 - 0.33 11.3 1.8 59 4.0 0.0 3.2 3 0 0 3 3 3 0 Sigma factor regulator N-terminal DUF3698 PF12479.8 KRZ99907.1 - 2.1e-24 86.1 0.0 3.8e-24 85.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3698) DUF1981 PF09324.10 KRZ99907.1 - 0.16 11.9 0.2 0.7 9.8 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1981) Fungal_trans PF04082.18 KRZ99908.1 - 7e-21 74.5 0.7 1.1e-20 73.8 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain LAT PF15234.6 KRZ99908.1 - 0.98 9.1 9.2 0.21 11.3 5.8 1.5 2 0 0 2 2 2 0 Linker for activation of T-cells NAD_binding_10 PF13460.6 KRZ99909.1 - 3.5e-11 43.3 0.0 4.8e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KRZ99909.1 - 1.1e-09 38.1 0.0 1.1e-07 31.6 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KRZ99909.1 - 3.3e-07 30.1 0.0 5.7e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 KRZ99909.1 - 4.2e-05 23.8 0.1 6.3e-05 23.2 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain GDP_Man_Dehyd PF16363.5 KRZ99909.1 - 0.00029 20.3 0.0 0.0005 19.6 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KRZ99909.1 - 0.0019 17.3 0.2 0.0057 15.8 0.1 1.7 2 0 0 2 2 2 1 RmlD substrate binding domain adh_short PF00106.25 KRZ99909.1 - 0.011 15.2 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 0 short chain dehydrogenase 3Beta_HSD PF01073.19 KRZ99909.1 - 0.019 14.0 0.0 0.027 13.5 0.0 1.4 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.20 KRZ99909.1 - 0.03 14.4 0.0 0.049 13.7 0.0 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus TrkA_N PF02254.18 KRZ99909.1 - 0.036 14.3 0.0 0.054 13.7 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.18 KRZ99909.1 - 0.051 13.4 0.0 0.071 13.0 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KRZ99909.1 - 0.057 14.0 0.0 0.1 13.2 0.0 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 KRZ99909.1 - 0.085 12.5 0.0 1.1 8.9 0.0 2.1 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Aa_trans PF01490.18 KRZ99910.1 - 2.7e-11 42.8 29.0 4.4e-11 42.1 29.0 1.4 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein AbiEi_3_N PF17194.4 KRZ99910.1 - 0.024 14.6 0.3 18 5.5 0.0 3.2 2 1 1 3 3 3 0 Transcriptional regulator, AbiEi antitoxin N-terminal domain DUF2561 PF10812.8 KRZ99910.1 - 0.068 13.2 0.4 0.068 13.2 0.4 3.3 2 2 2 4 4 4 0 Protein of unknown function (DUF2561) Aa_trans PF01490.18 KRZ99911.1 - 0.0016 17.2 0.3 0.0019 17.0 0.3 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KRZ99911.1 - 0.016 14.3 0.4 0.018 14.1 0.4 1.1 1 0 0 1 1 1 0 Tryptophan/tyrosine permease family DHDPS PF00701.22 KRZ99912.1 - 5.8e-59 199.2 0.0 6.6e-59 199.0 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family PEP_mutase PF13714.6 KRZ99912.1 - 1.6e-05 24.5 0.0 4.2e-05 23.1 0.0 1.6 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase FMN_dh PF01070.18 KRZ99913.1 - 8.3e-118 393.4 0.0 9.6e-118 393.2 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 KRZ99913.1 - 2.7e-08 33.2 0.2 5.8e-08 32.1 0.2 1.5 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 KRZ99913.1 - 1.3e-07 31.3 0.0 7.1e-05 22.4 0.0 3.0 3 0 0 3 3 3 2 Histidine biosynthesis protein NMO PF03060.15 KRZ99913.1 - 1.5e-06 27.8 0.3 2.8e-06 27.0 0.3 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase Glu_synthase PF01645.17 KRZ99913.1 - 3.5e-06 26.4 0.3 1.1e-05 24.8 0.3 1.7 1 1 0 1 1 1 1 Conserved region in glutamate synthase Dus PF01207.17 KRZ99913.1 - 0.00097 18.3 0.1 0.87 8.6 0.0 2.3 1 1 1 2 2 2 2 Dihydrouridine synthase (Dus) ThiG PF05690.14 KRZ99913.1 - 0.023 14.0 0.4 0.28 10.5 0.0 2.3 1 1 0 2 2 2 0 Thiazole biosynthesis protein ThiG DHO_dh PF01180.21 KRZ99913.1 - 0.071 12.3 0.2 0.8 8.9 0.0 2.3 2 1 1 3 3 3 0 Dihydroorotate dehydrogenase Aldedh PF00171.22 KRZ99914.1 - 7.4e-178 591.8 1.4 8.3e-178 591.6 1.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KRZ99914.1 - 0.0032 16.9 0.1 0.039 13.4 0.1 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) SpoIIAA-like PF11964.8 KRZ99914.1 - 0.063 14.3 0.0 4.2 8.5 0.0 2.8 2 1 0 2 2 2 0 SpoIIAA-like DUF5063 PF16702.5 KRZ99914.1 - 0.15 12.4 0.0 0.46 10.9 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5063) PMM PF03332.13 KRZ99915.1 - 1.9e-111 371.1 0.9 2.2e-111 370.9 0.9 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 KRZ99915.1 - 3.4e-07 30.3 0.0 1.5e-05 24.9 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 KRZ99915.1 - 0.001 18.7 0.0 1.3 8.4 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 KRZ99915.1 - 0.09 13.1 0.0 0.31 11.3 0.0 1.8 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Trehalose_PPase PF02358.16 KRZ99915.1 - 0.18 10.9 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 Trehalose-phosphatase RCC1 PF00415.18 KRZ99916.1 - 4.7e-16 59.1 0.4 0.0032 18.1 0.0 5.4 6 0 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KRZ99916.1 - 1e-15 57.1 2.5 6.6e-06 25.8 0.0 4.0 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat DUF1640 PF07798.11 KRZ99917.1 - 1.4e-56 191.3 9.0 1.6e-56 191.1 9.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) FlaC_arch PF05377.11 KRZ99917.1 - 0.025 15.0 3.9 0.76 10.2 0.5 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) XhlA PF10779.9 KRZ99917.1 - 0.04 14.1 6.7 0.38 11.0 0.1 2.4 2 0 0 2 2 2 0 Haemolysin XhlA HalX PF08663.10 KRZ99917.1 - 0.081 13.2 0.7 3.5 8.0 0.1 2.3 2 0 0 2 2 2 0 HalX domain HALZ PF02183.18 KRZ99917.1 - 0.082 13.1 3.8 0.18 12.0 3.8 1.6 1 1 0 1 1 1 0 Homeobox associated leucine zipper DUF3158 PF11358.8 KRZ99917.1 - 0.11 12.3 2.9 0.12 12.1 1.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3158) DUF5082 PF16888.5 KRZ99917.1 - 0.27 11.5 8.9 2.1 8.6 8.1 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) PspA_IM30 PF04012.12 KRZ99917.1 - 0.49 9.9 8.1 3.6 7.1 2.0 2.1 2 0 0 2 2 2 0 PspA/IM30 family Uds1 PF15456.6 KRZ99917.1 - 0.57 10.3 6.0 0.98 9.6 5.4 1.7 2 0 0 2 2 2 0 Up-regulated During Septation Fungal_TACC PF12709.7 KRZ99917.1 - 0.68 10.4 9.3 1.9 9.0 3.4 2.6 2 1 1 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins SlyX PF04102.12 KRZ99917.1 - 1.1 9.9 5.8 37 5.0 0.3 3.2 2 1 0 2 2 2 0 SlyX Lectin_N PF03954.14 KRZ99917.1 - 1.4 8.7 7.2 1.1 9.0 3.8 2.2 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain Spc24 PF08286.11 KRZ99917.1 - 2.4 8.4 9.1 15 5.9 6.4 2.6 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 YabA PF06156.13 KRZ99917.1 - 5.1 7.8 9.3 4.7 7.9 3.2 2.3 1 1 0 2 2 2 0 Initiation control protein YabA V-SNARE_C PF12352.8 KRZ99918.1 - 4.3e-10 39.7 0.4 1e-09 38.5 0.4 1.7 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 KRZ99918.1 - 8.1e-09 35.3 2.6 2.9e-08 33.5 0.0 2.6 2 1 1 3 3 3 1 Sec20 Sigma70_r4 PF04545.16 KRZ99918.1 - 0.0086 15.6 0.0 0.019 14.5 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 V_ATPase_I PF01496.19 KRZ99918.1 - 0.039 11.9 8.1 0.051 11.5 8.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MeaB PF03308.16 KRZ99918.1 - 0.058 12.4 0.2 0.081 11.9 0.2 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB EzrA PF06160.12 KRZ99918.1 - 0.073 11.2 11.1 1.3 7.1 1.9 2.2 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA DUF4047 PF13256.6 KRZ99918.1 - 0.31 11.2 8.0 5.1 7.3 0.3 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4047) Fur_reg_FbpB PF13040.6 KRZ99918.1 - 0.37 10.4 4.0 1.7 8.3 0.3 3.3 3 0 0 3 3 3 0 Fur-regulated basic protein B DUF4407 PF14362.6 KRZ99918.1 - 1.8 7.8 17.9 3 7.1 17.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Seryl_tRNA_N PF02403.22 KRZ99918.1 - 2.3 8.5 8.7 1.8 8.8 4.1 2.3 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Allexi_40kDa PF05549.11 KRZ99918.1 - 5.4 6.4 9.0 1.1 8.7 4.6 1.8 1 1 1 2 2 2 0 Allexivirus 40kDa protein Glyco_hydro_17 PF00332.18 KRZ99919.1 - 4.4e-11 43.0 1.6 1e-10 41.8 1.3 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 GT87 PF09594.10 KRZ99919.1 - 0.031 14.0 0.2 0.055 13.2 0.2 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 87 TSP9 PF11493.8 KRZ99919.1 - 0.17 12.6 0.3 0.17 12.6 0.3 2.5 3 0 0 3 3 3 0 Thylakoid soluble phosphoprotein TSP9 Bromodomain PF00439.25 KRZ99920.1 - 5e-27 93.8 0.8 1.9e-15 56.7 0.5 2.8 2 0 0 2 2 2 2 Bromodomain BAH PF01426.18 KRZ99920.1 - 1.4e-18 66.9 0.0 3.2e-18 65.7 0.0 1.7 1 0 0 1 1 1 1 BAH domain SIR2 PF02146.17 KRZ99921.1 - 2.7e-39 134.9 0.0 6.2e-39 133.7 0.0 1.6 1 1 0 1 1 1 1 Sir2 family Glyco_transf_28 PF03033.20 KRZ99921.1 - 0.18 11.8 0.0 0.38 10.8 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain Zn-ribbon_8 PF09723.10 KRZ99921.1 - 0.64 10.2 2.6 0.41 10.8 0.3 1.8 2 0 0 2 2 2 0 Zinc ribbon domain DUF2385 PF09539.10 KRZ99922.1 - 0.062 13.8 0.0 0.63 10.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2385) Pyr_redox_2 PF07992.14 KRZ99923.1 - 4.8e-67 226.2 4.4 4.8e-67 226.2 4.4 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KRZ99923.1 - 9.9e-43 144.9 0.2 2.2e-42 143.8 0.2 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KRZ99923.1 - 6.6e-18 65.0 11.4 2.2e-17 63.4 1.9 3.3 4 0 0 4 4 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KRZ99923.1 - 9.3e-13 48.0 6.0 1.3e-11 44.2 0.7 2.6 2 1 1 3 3 3 2 Glucose inhibited division protein A NAD_binding_8 PF13450.6 KRZ99923.1 - 1e-09 38.5 1.6 0.00098 19.3 0.1 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KRZ99923.1 - 5.6e-09 35.7 4.0 1.6e-06 27.6 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KRZ99923.1 - 9.7e-08 31.8 0.1 9.7e-08 31.8 0.1 3.3 3 1 1 4 4 4 1 FAD dependent oxidoreductase Thi4 PF01946.17 KRZ99923.1 - 1.3e-06 27.9 2.6 0.00012 21.4 0.1 2.4 2 0 0 2 2 2 2 Thi4 family FAD_binding_2 PF00890.24 KRZ99923.1 - 6.9e-06 25.4 4.9 1.6e-05 24.2 0.7 2.9 3 0 0 3 3 3 1 FAD binding domain K_oxygenase PF13434.6 KRZ99923.1 - 1.2e-05 24.6 0.6 0.081 12.1 0.0 2.8 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 KRZ99923.1 - 1.4e-05 24.0 9.0 0.003 16.3 0.5 4.0 4 0 0 4 4 4 2 HI0933-like protein AlaDh_PNT_C PF01262.21 KRZ99923.1 - 2.9e-05 23.4 2.9 0.0065 15.8 0.1 3.3 3 1 1 4 4 4 1 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 KRZ99923.1 - 0.00016 20.9 0.1 0.02 14.0 0.0 2.6 3 0 0 3 3 3 1 Lycopene cyclase protein FAD_binding_3 PF01494.19 KRZ99923.1 - 0.00019 20.8 5.2 0.021 14.1 1.0 2.9 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.24 KRZ99923.1 - 0.0026 17.4 15.3 0.19 11.3 1.5 4.1 2 2 1 4 4 4 1 FAD dependent oxidoreductase 3HCDH_N PF02737.18 KRZ99923.1 - 0.016 15.1 0.7 0.016 15.1 0.7 2.2 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 KRZ99923.1 - 0.39 10.3 2.7 0.17 11.5 0.2 1.7 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain tRNA-synt_2d PF01409.20 KRZ99924.1 - 2.9e-88 295.5 0.0 4.3e-88 294.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 KRZ99924.1 - 5.5e-15 55.4 2.2 7.8e-15 54.9 0.5 2.3 2 0 0 2 2 2 1 PheRS DNA binding domain 3 tRNA_synthFbeta PF17759.1 KRZ99924.1 - 8.7e-08 31.9 0.0 6.1e-06 25.8 0.0 2.2 2 0 0 2 2 2 1 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2 PF00152.20 KRZ99924.1 - 7.3e-05 22.0 0.0 0.0016 17.5 0.0 2.6 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) PheRS_DBD2 PF18554.1 KRZ99924.1 - 0.00066 19.6 2.4 0.0016 18.4 2.4 1.7 1 0 0 1 1 1 1 PheRS DNA binding domain 2 tRNA-synt_2b PF00587.25 KRZ99924.1 - 0.00073 19.6 0.0 0.0014 18.6 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) zf-H2C2_2 PF13465.6 KRZ99925.1 - 6.8e-06 26.3 3.7 6.8e-06 26.3 3.7 2.9 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2 PF00096.26 KRZ99925.1 - 0.00034 20.9 15.8 0.0035 17.7 0.3 3.7 3 1 0 3 3 3 2 Zinc finger, C2H2 type FOXP-CC PF16159.5 KRZ99925.1 - 0.0093 16.6 21.9 0.21 12.2 0.2 5.0 4 1 1 5 5 5 2 FOXP coiled-coil domain zf-C2H2_3rep PF18868.1 KRZ99925.1 - 0.021 15.5 5.8 2 9.1 0.0 3.0 3 1 0 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_4 PF13894.6 KRZ99925.1 - 0.043 14.7 13.6 0.049 14.5 0.4 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger Zap1_zf2 PF18217.1 KRZ99925.1 - 0.23 11.5 3.5 0.3 11.1 0.1 2.8 2 0 0 2 2 2 0 Zap1 zinc finger 2 zf-C2H2_6 PF13912.6 KRZ99925.1 - 0.67 10.0 3.9 13 5.9 0.1 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger zf_ZIC PF18366.1 KRZ99925.1 - 1.2 9.3 6.1 1.1 9.4 1.5 2.9 2 1 0 2 2 2 0 Zic proteins zinc finger domain Tubulin PF00091.25 KRZ99926.1 - 8.2e-43 146.9 0.0 2e-42 145.6 0.0 1.7 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KRZ99926.1 - 3.3e-13 49.9 0.5 5.7e-13 49.1 0.5 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_2 PF13809.6 KRZ99926.1 - 0.0042 16.3 0.0 0.0069 15.6 0.0 1.5 1 0 0 1 1 1 1 Tubulin like BAR_2 PF10455.9 KRZ99927.1 - 2.3e-63 214.0 2.3 3.4e-63 213.5 2.3 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 KRZ99927.1 - 3.4e-15 56.4 1.6 1.3e-14 54.4 1.6 1.9 1 1 0 1 1 1 1 BAR domain Arfaptin PF06456.13 KRZ99927.1 - 7.7e-05 22.4 0.2 0.033 13.8 0.0 2.3 2 0 0 2 2 2 2 Arfaptin-like domain Csm2_III-A PF03750.13 KRZ99927.1 - 0.00037 21.3 1.8 0.0042 17.9 0.6 2.5 2 1 0 2 2 2 1 Csm2 Type III-A Tht1 PF04163.12 KRZ99927.1 - 0.28 9.9 7.1 0.18 10.6 1.0 2.1 2 0 0 2 2 2 0 Tht1-like nuclear fusion protein AA_kinase PF00696.28 KRZ99928.1 - 5.6e-45 153.8 0.4 1.1e-44 152.9 0.0 1.7 2 1 0 2 2 2 1 Amino acid kinase family ACT PF01842.25 KRZ99928.1 - 2.5e-07 30.3 5.1 0.0006 19.5 0.3 3.2 3 0 0 3 3 3 2 ACT domain ACT_7 PF13840.6 KRZ99928.1 - 1.8e-06 27.7 2.0 9.1e-05 22.2 0.4 2.5 2 0 0 2 2 2 1 ACT domain CLP1_P PF16575.5 KRZ99928.1 - 0.091 12.6 0.1 0.28 11.0 0.0 1.8 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop DUF2250 PF10007.9 KRZ99928.1 - 0.098 12.8 0.5 0.71 10.0 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) RnlA_toxin PF15935.5 KRZ99928.1 - 0.19 11.5 3.7 0.37 10.6 0.5 2.3 2 0 0 2 2 2 0 RNase LS, bacterial toxin KIP1 PF07765.12 KRZ99928.1 - 0.37 10.9 1.3 0.66 10.1 0.2 1.9 2 0 0 2 2 2 0 KIP1-like protein Ofd1_CTDD PF10637.9 KRZ99929.1 - 2.8e-93 312.0 0.1 1.6e-91 306.2 0.1 2.2 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 KRZ99929.1 - 5.1e-26 91.2 0.0 1.6e-25 89.6 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 KRZ99929.1 - 4.4e-14 53.1 0.0 8.9e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 KRZ99929.1 - 0.021 15.3 0.0 0.18 12.3 0.0 2.4 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily NAD_binding_1 PF00175.21 KRZ99930.1 - 3.3e-34 117.8 0.0 5.2e-34 117.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KRZ99930.1 - 5.7e-32 110.0 0.0 1.3e-31 108.8 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KRZ99930.1 - 1.3e-05 25.3 0.0 0.00044 20.4 0.0 2.1 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Choline_transpo PF04515.12 KRZ99930.1 - 0.19 10.9 0.0 1.6 7.9 0.1 1.9 2 0 0 2 2 2 0 Plasma-membrane choline transporter Vps62 PF06101.11 KRZ99931.1 - 4.1e-10 38.6 4.3 8e-10 37.6 4.3 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 62 AA_permease PF00324.21 KRZ99932.1 - 7.6e-141 470.0 43.1 9.3e-141 469.7 43.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KRZ99932.1 - 1.2e-33 116.6 45.8 1.4e-33 116.4 45.8 1.0 1 0 0 1 1 1 1 Amino acid permease DUF4781 PF16013.5 KRZ99932.1 - 0.23 10.2 0.9 0.54 9.0 0.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) DUF3384 PF11864.8 KRZ99933.1 - 1.1e-92 311.5 16.7 4.3e-92 309.5 16.7 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.15 KRZ99933.1 - 1.7e-47 161.4 0.6 3.5e-47 160.4 0.6 1.6 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.16 KRZ99933.1 - 8.9e-27 94.1 3.5 8.9e-25 87.5 2.3 2.9 2 0 0 2 2 2 2 Tuberin Acid_PPase PF12689.7 KRZ99933.1 - 2.7 7.8 5.2 8.2 6.2 0.0 4.0 5 0 0 5 5 5 0 Acid Phosphatase SIS PF01380.22 KRZ99934.1 - 4.5e-12 45.9 0.1 8.6e-12 45.0 0.1 1.4 1 0 0 1 1 1 1 SIS domain SIS_2 PF13580.6 KRZ99934.1 - 0.01 15.9 0.1 0.53 10.3 0.1 2.4 1 1 1 2 2 2 0 SIS domain PUF PF00806.19 KRZ99935.1 - 2.8e-59 193.6 14.3 3.8e-08 32.6 0.0 8.7 9 0 0 9 9 9 8 Pumilio-family RNA binding repeat CPL PF08144.11 KRZ99935.1 - 3.8e-05 24.1 0.2 0.47 10.8 0.0 4.1 3 1 0 3 3 3 2 CPL (NUC119) domain THP2 PF09432.10 KRZ99935.1 - 0.088 12.9 1.8 0.18 11.9 0.5 2.0 2 0 0 2 2 2 0 Tho complex subunit THP2 PriX PF18689.1 KRZ99935.1 - 0.11 12.8 1.2 3.5 8.0 0.4 2.9 2 1 0 2 2 2 0 Primase X BRAP2 PF07576.12 KRZ99936.1 - 0.00029 21.0 0.4 0.00076 19.7 0.0 1.9 2 0 0 2 2 2 1 BRCA1-associated protein 2 WD40 PF00400.32 KRZ99937.1 - 9.3e-06 26.3 3.7 0.06 14.3 0.0 4.7 3 1 1 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KRZ99937.1 - 7.8e-05 22.9 0.3 0.87 9.9 0.0 3.9 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain TPR_2 PF07719.17 KRZ99938.1 - 4.9e-28 94.9 23.1 0.00021 21.2 0.3 11.8 14 0 0 14 14 14 7 Tetratricopeptide repeat TPR_1 PF00515.28 KRZ99938.1 - 2e-27 93.9 25.1 5.4e-05 22.8 0.5 10.6 12 0 0 12 12 12 6 Tetratricopeptide repeat ANAPC3 PF12895.7 KRZ99938.1 - 2.4e-25 88.6 19.1 7e-23 80.7 0.4 5.4 5 0 0 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 KRZ99938.1 - 4.8e-19 66.9 17.8 4.4e-05 23.4 0.3 9.4 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_12 PF13424.6 KRZ99938.1 - 1.5e-16 60.4 16.7 0.0001 22.5 0.0 9.4 7 3 4 12 12 11 5 Tetratricopeptide repeat TPR_19 PF14559.6 KRZ99938.1 - 7.4e-16 58.4 5.6 0.023 15.2 0.0 6.8 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 KRZ99938.1 - 6.6e-14 51.4 0.4 0.059 14.2 0.0 8.7 8 2 2 10 10 8 1 Tetratricopeptide repeat TPR_17 PF13431.6 KRZ99938.1 - 3.3e-12 45.9 14.0 0.13 12.7 0.0 9.1 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_16 PF13432.6 KRZ99938.1 - 1.5e-10 41.5 3.3 1.1 10.0 0.0 7.4 8 2 0 8 8 7 2 Tetratricopeptide repeat TPR_6 PF13174.6 KRZ99938.1 - 5.4e-10 39.3 2.5 1.4 9.7 0.1 7.9 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_11 PF13414.6 KRZ99938.1 - 6.4e-08 32.2 6.5 0.019 14.6 0.0 7.1 7 1 1 8 8 8 3 TPR repeat TPR_10 PF13374.6 KRZ99938.1 - 4.7e-07 29.5 5.9 6.1 6.9 0.0 8.3 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_7 PF13176.6 KRZ99938.1 - 4.7e-07 29.4 10.8 1.1 9.5 0.1 8.5 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_9 PF13371.6 KRZ99938.1 - 4.3e-06 26.8 0.0 0.013 15.6 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KRZ99938.1 - 5.2e-06 26.1 0.3 0.00063 19.2 0.0 3.8 5 0 0 5 5 5 1 MalT-like TPR region TPR_15 PF13429.6 KRZ99938.1 - 0.00013 21.3 0.0 1.6 7.8 0.0 3.7 3 1 1 4 4 4 2 Tetratricopeptide repeat Coatomer_E PF04733.14 KRZ99938.1 - 0.011 15.2 2.6 0.17 11.3 0.2 3.7 4 1 1 5 5 5 0 Coatomer epsilon subunit Acetone_carb_G PF08882.11 KRZ99938.1 - 0.027 14.6 0.1 0.082 13.1 0.1 1.7 1 0 0 1 1 1 0 Acetone carboxylase gamma subunit WD40 PF00400.32 KRZ99939.1 - 9.6e-24 83.2 10.3 1.4e-06 28.9 0.1 6.6 6 2 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KRZ99939.1 - 1.2e-10 41.5 1.4 0.013 15.8 0.1 4.8 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 KRZ99939.1 - 2.5e-05 24.2 1.1 0.4 10.7 0.2 4.3 3 1 1 4 4 4 2 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.8 KRZ99939.1 - 0.00028 19.7 1.2 0.081 11.5 0.0 2.7 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KRZ99939.1 - 0.00045 19.1 4.2 2 7.1 0.3 3.9 2 1 1 3 3 3 3 Nup133 N terminal like BRE PF06113.12 KRZ99939.1 - 0.016 14.0 0.0 0.026 13.3 0.0 1.2 1 0 0 1 1 1 0 Brain and reproductive organ-expressed protein (BRE) Big_2 PF02368.18 KRZ99939.1 - 0.085 12.8 0.1 0.5 10.3 0.1 2.4 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 2) AlaDh_PNT_N PF05222.15 KRZ99940.1 - 8.2e-31 107.1 0.0 1.4e-30 106.4 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain Peptidase_Mx PF15887.5 KRZ99941.1 - 0.033 13.6 0.0 0.061 12.7 0.0 1.3 1 0 0 1 1 1 0 Putative zinc-binding metallo-peptidase FGGY_N PF00370.21 KRZ99942.1 - 1.3e-14 54.4 0.0 4.6e-08 32.9 0.0 3.4 1 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 KRZ99942.1 - 1.2e-13 51.2 0.0 5e-13 49.2 0.0 2.0 2 1 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FAE1_CUT1_RppA PF08392.12 KRZ99942.1 - 0.059 12.7 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 FAE1/Type III polyketide synthase-like protein Hap4_Hap_bind PF10297.9 KRZ99943.1 - 9.7e-09 35.1 8.8 2e-08 34.1 8.8 1.6 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 TSC22 PF01166.18 KRZ99943.1 - 0.13 12.6 1.3 0.28 11.5 0.3 2.1 2 0 0 2 2 2 0 TSC-22/dip/bun family FAM110_C PF14160.6 KRZ99943.1 - 0.74 10.9 4.7 0.38 11.8 0.3 2.3 2 1 0 2 2 2 0 Centrosome-associated C terminus Arm PF00514.23 KRZ99944.1 - 5.9e-85 277.0 16.6 6.1e-13 48.3 0.2 8.6 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 KRZ99944.1 - 5.7e-25 87.6 9.8 5.7e-25 87.6 9.8 2.3 3 0 0 3 3 3 1 Importin beta binding domain HEAT_EZ PF13513.6 KRZ99944.1 - 9.2e-25 86.7 1.4 1.4e-06 28.7 0.1 6.2 4 2 2 6 6 6 6 HEAT-like repeat Arm_3 PF16186.5 KRZ99944.1 - 1.5e-21 75.7 6.1 3e-21 74.7 6.1 1.6 1 0 0 1 1 1 1 Atypical Arm repeat HEAT PF02985.22 KRZ99944.1 - 3.4e-17 61.0 0.1 0.038 14.3 0.0 7.4 7 0 0 7 7 7 4 HEAT repeat HEAT_2 PF13646.6 KRZ99944.1 - 1.3e-14 54.4 0.8 0.00011 22.5 0.0 5.0 2 2 4 6 6 6 4 HEAT repeats V-ATPase_H_C PF11698.8 KRZ99944.1 - 1.8e-05 24.8 0.5 0.5 10.5 0.0 4.4 4 1 0 4 4 4 2 V-ATPase subunit H RICTOR_V PF14668.6 KRZ99944.1 - 0.00016 21.9 2.4 1.8 8.8 0.0 4.8 5 1 1 6 6 6 1 Rapamycin-insensitive companion of mTOR, domain 5 Arm_2 PF04826.13 KRZ99944.1 - 0.00022 20.8 4.3 2.7 7.4 0.0 4.7 3 1 2 5 5 5 2 Armadillo-like DUF2704 PF10866.8 KRZ99945.1 - 0.11 12.3 0.5 0.16 11.8 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2704) Usp PF00582.26 KRZ99946.1 - 4.7e-08 33.6 1.3 3.1e-07 31.0 0.0 2.6 2 1 0 2 2 2 1 Universal stress protein family Far-17a_AIG1 PF04750.14 KRZ99947.1 - 1.1e-17 64.0 12.1 1.3e-17 63.8 12.1 1.1 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Far-17a_AIG1 PF04750.14 KRZ99948.1 - 2.1e-14 53.3 7.9 2.1e-14 53.3 7.9 1.3 1 1 0 1 1 1 1 FAR-17a/AIG1-like protein Peptidase_M14 PF00246.24 KRZ99949.1 - 1.8e-64 218.3 0.2 2.6e-64 217.8 0.2 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase Tyr_Deacylase PF02580.16 KRZ99950.1 - 2.5e-29 102.6 0.0 2.9e-29 102.5 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Aa_trans PF01490.18 KRZ99951.1 - 1.1e-31 110.0 33.0 1.4e-31 109.6 33.0 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Endosulfine PF04667.17 KRZ99953.1 - 3.3e-31 107.3 1.0 4.4e-31 106.8 1.0 1.2 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region Autophagy_act_C PF03987.15 KRZ99954.1 - 4.8e-12 46.3 0.3 1.1e-11 45.1 0.3 1.7 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain SKA1 PF07160.12 KRZ99954.1 - 0.0053 16.6 1.0 0.0077 16.1 1.0 1.1 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 1 INSIG PF07281.12 KRZ99956.1 - 4.3e-26 91.9 3.5 5e-26 91.7 3.0 1.4 1 1 0 1 1 1 1 Insulin-induced protein (INSIG) WLM PF08325.10 KRZ99957.1 - 5.7e-52 176.6 0.1 5.7e-52 176.6 0.1 2.4 2 0 0 2 2 2 1 WLM domain DUF45 PF01863.17 KRZ99957.1 - 0.56 10.2 0.0 0.56 10.2 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function DUF45 Coilin_N PF15862.5 KRZ99957.1 - 9.1 6.1 23.6 3 7.6 15.9 3.2 2 1 0 2 2 2 0 Coilin N-terminus HK PF02110.15 KRZ99958.1 - 5.1e-64 216.0 2.6 1.4e-62 211.3 2.6 2.8 1 1 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.17 KRZ99958.1 - 9.7e-53 178.2 0.3 1.7e-52 177.4 0.3 1.4 1 0 0 1 1 1 1 Thiamine monophosphate synthase Phos_pyr_kin PF08543.12 KRZ99958.1 - 0.00036 20.0 1.6 0.0019 17.6 0.4 2.7 2 1 0 2 2 2 1 Phosphomethylpyrimidine kinase RNase_P_Rpp14 PF01900.19 KRZ99959.1 - 2.6e-36 124.0 0.0 3.4e-36 123.6 0.0 1.2 1 0 0 1 1 1 1 Rpp14/Pop5 family TPR_19 PF14559.6 KRZ99960.1 - 5.2e-24 84.5 7.5 1.5e-06 28.6 0.1 7.8 7 2 1 9 9 8 4 Tetratricopeptide repeat TPR_2 PF07719.17 KRZ99960.1 - 1.1e-20 72.0 23.3 0.22 11.7 0.3 11.4 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_16 PF13432.6 KRZ99960.1 - 4.3e-20 72.1 4.9 5e-05 23.9 0.0 7.2 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 KRZ99960.1 - 2.2e-14 52.6 22.8 0.074 12.9 0.1 10.1 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_17 PF13431.6 KRZ99960.1 - 2.6e-14 52.5 20.5 0.00021 21.4 0.0 8.9 11 0 0 11 11 7 4 Tetratricopeptide repeat TPR_12 PF13424.6 KRZ99960.1 - 5e-14 52.3 21.8 0.0065 16.7 1.7 8.3 6 4 2 8 8 7 4 Tetratricopeptide repeat TPR_11 PF13414.6 KRZ99960.1 - 9.2e-12 44.5 17.5 3.3e-05 23.5 0.2 7.5 6 2 3 9 9 9 3 TPR repeat TPR_14 PF13428.6 KRZ99960.1 - 2.6e-11 43.3 3.6 9.5 7.3 0.1 9.9 4 2 7 11 11 11 0 Tetratricopeptide repeat TPR_6 PF13174.6 KRZ99960.1 - 6.6e-10 39.0 11.1 0.76 10.6 0.0 9.1 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_7 PF13176.6 KRZ99960.1 - 2.2e-09 36.7 14.4 7.1 6.9 0.0 10.0 9 1 0 9 9 9 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KRZ99960.1 - 2.5e-07 30.8 18.9 0.00082 19.5 0.4 5.5 5 1 1 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 KRZ99960.1 - 4.2e-07 29.7 29.0 3.5 8.1 0.0 11.1 11 0 0 11 11 10 2 Tetratricopeptide repeat TPR_20 PF14561.6 KRZ99960.1 - 2e-05 24.8 5.2 3.2 8.2 0.0 6.1 4 1 2 6 6 6 1 Tetratricopeptide repeat TPR_9 PF13371.6 KRZ99960.1 - 3.9e-05 23.7 0.3 29 4.9 0.0 5.8 4 1 2 6 6 6 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 KRZ99960.1 - 9.7e-05 22.8 1.0 0.39 11.2 0.0 2.9 3 0 0 3 3 2 2 Alkyl sulfatase dimerisation TPR_15 PF13429.6 KRZ99960.1 - 0.002 17.4 5.8 1 8.5 0.0 4.5 3 2 3 6 6 6 2 Tetratricopeptide repeat TPR_10 PF13374.6 KRZ99960.1 - 0.0041 16.9 10.4 2.3 8.2 0.0 7.1 8 0 0 8 8 7 1 Tetratricopeptide repeat RPN7 PF10602.9 KRZ99960.1 - 0.044 13.5 12.2 0.93 9.2 0.3 6.0 5 1 2 7 7 7 0 26S proteasome subunit RPN7 TPR_3 PF07720.12 KRZ99960.1 - 0.11 12.5 1.4 6.1 7.0 0.0 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat BTAD PF03704.17 KRZ99960.1 - 1.1 9.7 6.0 22 5.4 0.0 4.2 4 1 1 5 5 5 0 Bacterial transcriptional activator domain Glyco_transf_24 PF18404.1 KRZ99961.1 - 3.1e-145 482.6 7.0 3.1e-145 482.6 7.0 1.9 2 0 0 2 2 2 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 KRZ99961.1 - 4.6e-39 134.9 8.9 7.4e-37 127.7 0.3 4.5 5 0 0 5 5 5 2 Thioredoxin-like domain Thioredoxin_12 PF18400.1 KRZ99961.1 - 1.5e-35 122.8 0.1 3.7e-35 121.5 0.1 1.7 1 0 0 1 1 1 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 KRZ99961.1 - 6.9e-24 84.1 0.0 1.6e-23 82.9 0.0 1.7 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Thioredoxin_13 PF18401.1 KRZ99961.1 - 7.1e-24 84.3 4.2 8.9e-24 83.9 0.2 3.0 2 1 1 3 3 3 1 Thioredoxin-like domain Thioredoxin_15 PF18403.1 KRZ99961.1 - 1.6e-07 31.5 3.6 2.1e-07 31.1 1.1 2.6 2 0 0 2 2 2 1 Thioredoxin-like domain Glyco_transf_8 PF01501.20 KRZ99961.1 - 3.8e-07 29.9 2.7 7.3e-07 29.0 1.9 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 8 DUF3740 PF12548.8 KRZ99961.1 - 0.021 15.2 1.4 0.17 12.3 0.0 2.9 3 0 0 3 3 3 0 Sulfatase protein MTHFR PF02219.17 KRZ99962.1 - 7e-117 389.8 0.0 1e-116 389.3 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Flocculin_t3 PF13928.6 KRZ99963.1 - 5.6e-20 71.6 56.6 1.7e-11 44.4 27.1 7.6 7 1 1 8 8 8 3 Flocculin type 3 repeat GATA PF00320.27 KRZ99964.1 - 6.4e-16 57.7 2.9 1.2e-15 56.8 2.9 1.5 1 0 0 1 1 1 1 GATA zinc finger zf-BED PF02892.15 KRZ99964.1 - 0.27 11.3 4.1 0.4 10.8 1.9 2.2 2 0 0 2 2 2 0 BED zinc finger Pkinase PF00069.25 KRZ99965.1 - 8.8e-48 162.9 0.5 1.4e-45 155.7 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KRZ99965.1 - 3.5e-26 92.0 0.0 1.2e-25 90.3 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KRZ99965.1 - 0.0092 15.3 0.0 0.033 13.5 0.0 1.8 1 1 1 2 2 2 1 Kinase-like Thioredoxin_7 PF13899.6 KRZ99966.1 - 3.2e-20 72.1 0.0 8.5e-20 70.7 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like UBX PF00789.20 KRZ99966.1 - 2e-11 43.9 0.1 6.4e-11 42.3 0.1 1.9 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 KRZ99966.1 - 2.6e-11 43.2 0.0 5e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain Mce4_CUP1 PF11887.8 KRZ99967.1 - 0.044 13.2 0.2 0.1 12.1 0.2 1.5 1 0 0 1 1 1 0 Cholesterol uptake porter CUP1 of Mce4, putative DNA_repr_REX1B PF14966.6 KRZ99967.1 - 0.16 12.6 7.2 0.067 13.9 1.2 3.0 2 0 0 2 2 2 0 DNA repair REX1-B Skp1 PF01466.19 KRZ99968.1 - 1e-23 83.1 0.4 2.5e-23 81.9 0.1 1.8 2 0 0 2 2 2 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 KRZ99968.1 - 1.5e-21 76.3 0.8 2.9e-21 75.4 0.8 1.5 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Peroxin-3 PF04882.12 KRZ99969.1 - 3.1e-106 356.2 24.4 1.4e-103 347.5 24.4 2.5 1 1 0 1 1 1 1 Peroxin-3 VASt PF16016.5 KRZ99970.1 - 6.3e-37 127.3 0.1 2e-36 125.7 0.1 1.9 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 KRZ99970.1 - 3.5e-29 101.0 0.1 7.4e-29 99.9 0.1 1.5 1 0 0 1 1 1 1 GRAM domain GARS_A PF01071.19 KRZ99971.1 - 2.5e-79 265.6 0.1 4.4e-79 264.8 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.15 KRZ99971.1 - 7.4e-34 116.4 0.2 8.4e-33 113.0 0.0 2.9 3 0 0 3 3 3 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.22 KRZ99971.1 - 1.9e-32 112.5 0.0 3.8e-32 111.6 0.0 1.5 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.16 KRZ99971.1 - 8.6e-25 86.8 0.2 1.9e-24 85.7 0.2 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 KRZ99971.1 - 7.6e-16 58.6 2.1 5.4e-15 55.8 2.8 2.1 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain ATP-grasp PF02222.22 KRZ99971.1 - 2.7e-05 23.8 0.1 9.2e-05 22.1 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_3 PF02655.14 KRZ99971.1 - 2.7e-05 24.2 0.1 0.00012 22.2 0.0 2.1 2 0 0 2 2 2 1 ATP-grasp domain CPSase_L_D2 PF02786.17 KRZ99971.1 - 0.00076 19.0 0.0 0.002 17.7 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_2 PF08442.10 KRZ99971.1 - 0.01 15.4 0.0 0.024 14.2 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain Ribonucleas_3_3 PF14622.6 KRZ99972.1 - 6.7e-05 23.1 0.1 0.0028 17.8 0.1 2.4 1 1 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 KRZ99972.1 - 0.0069 17.0 0.2 0.034 14.8 0.2 2.2 1 1 0 1 1 1 1 Ribonuclease III domain dsrm PF00035.26 KRZ99972.1 - 0.086 13.6 0.0 0.22 12.2 0.0 1.7 1 0 0 1 1 1 0 Double-stranded RNA binding motif EXS PF03124.14 KRZ99973.1 - 2.8e-69 234.0 25.4 3.2e-69 233.8 25.4 1.0 1 0 0 1 1 1 1 EXS family Nop25 PF09805.9 KRZ99974.1 - 1.1e-42 145.7 20.9 1.1e-42 145.7 20.9 2.4 2 1 0 2 2 2 1 Nucleolar protein 12 (25kDa) Med4 PF10018.9 KRZ99974.1 - 0.00049 19.8 5.4 0.00049 19.8 5.4 2.0 2 1 0 2 2 2 1 Vitamin-D-receptor interacting Mediator subunit 4 Sas10_Utp3 PF04000.15 KRZ99975.1 - 3.3e-16 59.7 1.7 3.3e-16 59.7 1.7 2.0 2 0 0 2 2 2 1 Sas10/Utp3/C1D family Ribonuc_2-5A PF06479.12 KRZ99976.1 - 1.2e-43 148.3 2.4 1.2e-43 148.3 2.4 2.1 2 0 0 2 2 2 1 Ribonuclease 2-5A Pkinase PF00069.25 KRZ99976.1 - 1.5e-39 135.9 0.0 1.3e-30 106.7 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KRZ99976.1 - 1e-21 77.4 0.0 2.6e-20 72.8 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase PQQ PF01011.21 KRZ99976.1 - 0.00014 21.6 0.0 0.1 12.6 0.0 3.3 3 0 0 3 3 3 2 PQQ enzyme repeat PQQ_2 PF13360.6 KRZ99976.1 - 0.00031 20.4 0.0 0.59 9.7 0.0 2.5 1 1 1 2 2 2 2 PQQ-like domain Pkinase_fungal PF17667.1 KRZ99976.1 - 0.00063 18.6 0.1 0.00063 18.6 0.1 2.7 2 1 1 3 3 3 1 Fungal protein kinase Vps51 PF08700.11 KRZ99977.1 - 7.6e-15 54.8 0.6 3.3e-14 52.7 0.6 2.2 1 0 0 1 1 1 1 Vps51/Vps67 PSDC PF12588.8 KRZ99977.1 - 0.0014 18.6 0.3 0.086 12.8 0.1 3.0 2 0 0 2 2 2 1 Phophatidylserine decarboxylase Nod1 PF17114.5 KRZ99977.1 - 0.021 15.0 7.5 3.6 7.7 0.2 3.9 3 0 0 3 3 3 0 Gef2-related medial cortical node protein Nod1 CMS1 PF14617.6 KRZ99978.1 - 4.4e-21 75.4 17.6 7.2e-15 55.0 1.0 2.9 1 1 2 3 3 3 2 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.29 KRZ99978.1 - 0.028 14.2 1.1 0.042 13.6 0.2 1.5 1 1 0 1 1 1 0 DEAD/DEAH box helicase Sec62 PF03839.16 KRZ99978.1 - 3.9 6.9 16.4 0.84 9.1 1.7 2.2 2 0 0 2 2 2 0 Translocation protein Sec62 GIDA PF01134.22 KRZ99979.1 - 4e-150 500.3 0.0 6.5e-150 499.6 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 KRZ99979.1 - 1.2e-61 208.6 0.0 1.8e-61 208.0 0.0 1.3 1 0 0 1 1 1 1 GidA associated domain Pyr_redox_2 PF07992.14 KRZ99979.1 - 0.00019 20.7 4.5 0.00049 19.4 0.8 2.6 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KRZ99979.1 - 0.00034 20.1 3.0 0.0032 16.9 0.7 2.9 3 0 0 3 3 3 1 FAD dependent oxidoreductase CTNNBL PF08216.11 KRZ99979.1 - 0.004 17.3 0.2 0.012 15.8 0.0 1.8 2 0 0 2 2 2 1 Catenin-beta-like, Arm-motif containing nuclear Pyr_redox PF00070.27 KRZ99979.1 - 0.013 16.1 0.1 0.05 14.2 0.1 2.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KRZ99979.1 - 0.019 14.2 0.0 0.049 12.9 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KRZ99979.1 - 0.036 13.1 0.4 0.15 11.1 0.4 1.9 1 1 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 KRZ99979.1 - 0.041 13.0 1.7 0.075 12.1 1.7 1.4 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.24 KRZ99979.1 - 0.07 12.7 2.0 5 6.6 0.9 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase Mito_morph_reg PF14972.6 KRZ99979.1 - 0.1 12.2 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial morphogenesis regulator OKR_DC_1_C PF03711.15 KRZ99979.1 - 0.12 12.7 0.1 6.2 7.1 0.0 2.4 2 0 0 2 2 2 0 Orn/Lys/Arg decarboxylase, C-terminal domain HI0933_like PF03486.14 KRZ99979.1 - 0.26 9.9 1.6 3.7 6.1 0.3 2.6 3 0 0 3 3 3 0 HI0933-like protein CENP-T_C PF15511.6 KRZ99980.1 - 1.1e-10 41.6 0.0 2.5e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID_20kDa PF03847.13 KRZ99980.1 - 0.0009 19.7 0.4 0.0038 17.7 0.1 2.2 2 0 0 2 2 2 1 Transcription initiation factor TFIID subunit A CENP-S PF15630.6 KRZ99980.1 - 0.083 13.3 0.2 0.39 11.1 0.0 2.2 2 0 0 2 2 2 0 CENP-S protein NAPRTase PF04095.16 KRZ99981.1 - 3.3e-68 229.9 0.0 4.3e-68 229.5 0.0 1.1 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 KRZ99981.1 - 7e-35 120.1 0.6 1.4e-34 119.1 0.6 1.6 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain DUF1940 PF09155.10 KRZ99981.1 - 0.12 12.5 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1940) IBN_N PF03810.19 KRZ99982.1 - 3.5e-16 58.9 0.4 3.5e-16 58.9 0.4 3.9 4 0 0 4 4 4 1 Importin-beta N-terminal domain HLH PF00010.26 KRZ99982.1 - 0.13 12.2 3.9 0.18 11.8 0.0 3.2 5 0 0 5 5 5 0 Helix-loop-helix DNA-binding domain CtaG_Cox11 PF04442.14 KRZ99983.1 - 1.3e-59 200.6 0.3 1.8e-59 200.1 0.3 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 Tugs PF17840.1 KRZ99983.1 - 0.075 13.2 0.9 0.15 12.3 0.9 1.4 1 0 0 1 1 1 0 Tethering Ubl4a to BAGS domain DUF3439 PF11921.8 KRZ99983.1 - 0.12 12.3 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) GTP1_OBG PF01018.22 KRZ99984.1 - 7.8e-41 139.2 0.7 3.7e-30 104.6 0.9 2.2 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.23 KRZ99984.1 - 9.2e-23 80.5 0.0 2.1e-22 79.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KRZ99984.1 - 4.7e-11 42.5 0.0 7.4e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Arf PF00025.21 KRZ99984.1 - 1.1e-08 34.7 0.1 3.7e-08 33.0 0.0 1.9 2 1 0 2 2 2 1 ADP-ribosylation factor family Sde2_N_Ubi PF13019.6 KRZ99984.1 - 0.0093 15.8 0.8 14 5.5 0.0 3.5 3 0 0 3 3 3 1 Silencing defective 2 N-terminal ubiquitin domain Ras PF00071.22 KRZ99984.1 - 0.011 15.4 0.1 0.033 13.8 0.0 1.8 2 0 0 2 2 2 0 Ras family ABC_tran PF00005.27 KRZ99984.1 - 0.066 13.7 0.0 0.17 12.4 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Dynamin_N PF00350.23 KRZ99984.1 - 0.071 13.2 0.9 13 5.8 0.0 2.8 2 1 1 3 3 3 0 Dynamin family ERCC4 PF02732.15 KRZ99984.1 - 0.087 13.0 0.0 0.21 11.8 0.0 1.7 1 0 0 1 1 1 0 ERCC4 domain DEAD PF00270.29 KRZ99985.1 - 3.6e-44 150.6 0.0 8.3e-44 149.4 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KRZ99985.1 - 1.3e-29 102.8 0.0 8.5e-29 100.1 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KRZ99985.1 - 3.9e-06 27.0 0.0 1.2e-05 25.4 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF202 PF02656.15 KRZ99986.1 - 3.8e-15 56.1 0.6 2.6e-14 53.4 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF373 PF04123.13 KRZ99986.1 - 0.0011 18.5 2.0 0.0013 18.2 2.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF373) COX1 PF00115.20 KRZ99986.1 - 0.0013 17.7 0.3 0.0016 17.4 0.3 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I Cation_ATPase_C PF00689.21 KRZ99986.1 - 0.011 15.5 0.7 0.014 15.1 0.7 1.2 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus Atthog PF18800.1 KRZ99986.1 - 0.7 9.8 6.1 0.099 12.5 0.5 2.1 1 1 1 2 2 2 0 Attenuator of Hedgehog Saf_2TM PF18303.1 KRZ99986.1 - 1.3 8.6 7.8 0.46 10.1 0.6 2.3 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain DUF1218 PF06749.12 KRZ99986.1 - 2.6 8.6 7.7 2.3 8.8 1.6 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1218) DHHC PF01529.20 KRZ99986.1 - 8.3 6.5 12.6 1.8 8.7 5.5 2.0 1 1 2 3 3 3 0 DHHC palmitoyltransferase Tetraspanin PF00335.20 KRZ99986.1 - 8.4 6.0 9.6 5.4 6.7 6.7 1.8 1 1 0 1 1 1 0 Tetraspanin family SUR7 PF06687.12 KRZ99986.1 - 9.8 5.7 13.1 32 4.1 13.1 1.8 1 1 0 1 1 1 0 SUR7/PalI family TFIIB PF00382.19 KRZ99987.1 - 1.6e-54 181.8 1.8 3.5e-26 91.0 0.3 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 KRZ99987.1 - 2.5e-29 101.6 0.2 2.5e-29 101.6 0.2 3.0 3 1 0 3 3 1 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.12 KRZ99987.1 - 4.5e-09 35.7 0.9 8.9e-09 34.7 0.9 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 KRZ99987.1 - 0.00031 20.5 0.1 0.6 9.9 0.0 2.7 2 0 0 2 2 2 2 Cyclin, N-terminal domain CdiA_C PF18451.1 KRZ99987.1 - 0.0083 16.3 5.3 0.051 13.8 1.4 2.9 2 0 0 2 2 2 1 Contact-dependent growth inhibition CdiA C-terminal domain ACP_PD PF04336.12 KRZ99987.1 - 0.074 13.5 0.4 3.4 8.2 0.0 2.8 2 0 0 2 2 2 0 Acyl carrier protein phosphodiesterase Zn-ribbon_8 PF09723.10 KRZ99987.1 - 0.26 11.5 0.5 0.71 10.0 0.5 1.7 1 0 0 1 1 1 0 Zinc ribbon domain DUF530 PF04409.12 KRZ99987.1 - 0.35 9.2 13.8 0.05 12.0 8.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF530) zf-ribbon_3 PF13248.6 KRZ99987.1 - 0.5 9.8 2.8 9.2 5.8 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain LMBR1 PF04791.16 KRZ99987.1 - 0.61 8.9 4.6 0.83 8.5 4.6 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Noggin PF05806.12 KRZ99987.1 - 1 9.2 4.0 11 5.8 0.0 2.7 2 0 0 2 2 2 0 Noggin DUF2121 PF09894.9 KRZ99987.1 - 1.4 8.4 6.7 2.7 7.5 0.0 3.2 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2121) Prominin PF05478.11 KRZ99987.1 - 7.4 4.4 9.1 12 3.7 9.1 1.3 1 0 0 1 1 1 0 Prominin SDA1 PF05285.12 KRZ99988.1 - 1.1e-97 327.6 34.9 1.1e-97 327.6 34.9 2.1 2 0 0 2 2 2 2 SDA1 NUC130_3NT PF08158.12 KRZ99988.1 - 6e-22 77.7 0.0 2.6e-21 75.7 0.1 2.2 2 0 0 2 2 2 1 NUC130/3NT domain DUF913 PF06025.12 KRZ99988.1 - 1.4 7.9 8.6 13 4.6 0.1 2.9 2 1 0 2 2 2 0 Domain of Unknown Function (DUF913) HMG_box PF00505.19 KRZ99989.1 - 2.7e-09 37.3 3.1 2.7e-09 37.3 3.1 2.1 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KRZ99989.1 - 3.1e-06 27.7 1.4 3.1e-06 27.7 1.4 2.4 2 0 0 2 2 2 1 HMG-box domain Acyl_transf_1 PF00698.21 KRZ99990.1 - 3.3e-14 53.1 0.0 4.3e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 Acyl transferase domain PmrD PF11183.8 KRZ99990.1 - 0.085 13.0 0.5 0.87 9.7 0.2 2.4 3 0 0 3 3 3 0 Polymyxin resistance protein PmrD FTHFS PF01268.19 KRZ99991.1 - 7.3e-257 853.0 0.1 9.1e-257 852.7 0.1 1.1 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 KRZ99991.1 - 9.9e-63 210.2 0.3 3e-62 208.7 0.2 1.9 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 KRZ99991.1 - 5.2e-37 126.7 1.7 1.4e-36 125.3 1.7 1.8 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GTP_EFTU PF00009.27 KRZ99991.1 - 0.083 12.4 0.2 0.23 10.9 0.0 1.8 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain CbiA PF01656.23 KRZ99991.1 - 0.14 12.2 0.1 0.63 10.1 0.1 2.0 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Helicase_C_4 PF13871.6 KRZ99991.1 - 0.17 11.6 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 C-terminal domain on Strawberry notch homologue Rhodanese PF00581.20 KRZ99992.1 - 4.3e-18 65.8 0.0 6.5e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain RRP36 PF06102.12 KRZ99993.1 - 6.7e-48 162.8 26.7 6.7e-48 162.8 26.7 1.9 2 0 0 2 2 2 1 rRNA biogenesis protein RRP36 ATP-grasp_2 PF08442.10 KRZ99994.1 - 3.7e-43 147.5 0.2 8e-43 146.4 0.1 1.6 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.19 KRZ99994.1 - 1.1e-23 83.7 0.3 2.2e-23 82.8 0.1 1.6 2 0 0 2 2 2 1 CoA-ligase VID27_N PF17748.1 KRZ99994.1 - 0.1 12.4 0.1 0.16 11.8 0.1 1.2 1 0 0 1 1 1 0 VID27 N-terminal region Proteasome PF00227.26 KRZ99995.1 - 3.6e-54 183.2 0.1 4.6e-54 182.8 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KRZ99995.1 - 2.4e-12 46.3 0.0 5.2e-12 45.2 0.0 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature CppA_C PF14507.6 KRZ99995.1 - 0.1 13.3 0.2 0.25 12.1 0.2 1.6 1 0 0 1 1 1 0 CppA C-terminal GCP_N_terminal PF17681.1 KRZ99996.1 - 8.4e-39 134.0 1.2 1.6e-38 133.1 1.2 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 KRZ99996.1 - 2.9e-21 76.3 9.0 2.9e-21 76.3 9.0 1.7 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal Chalcone_N PF18232.1 KRZ99996.1 - 0.049 14.0 0.1 0.22 11.9 0.0 2.1 2 0 0 2 2 2 0 Chalcone isomerase N-terminal domain AAA_lid_1 PF17857.1 KRZ99996.1 - 0.069 13.4 3.8 0.099 12.9 0.7 2.9 2 0 0 2 2 2 0 AAA+ lid domain ATG7_N PF16420.5 KRZ99997.1 - 2.8e-59 201.2 3.3 7.9e-59 199.7 3.3 1.8 1 1 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 KRZ99997.1 - 2.4e-43 148.3 0.0 3.6e-43 147.7 0.0 1.2 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 KRZ99997.1 - 0.018 15.1 0.0 0.19 11.8 0.0 2.3 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 KRZ99997.1 - 0.02 14.2 0.0 0.4 10.0 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NMD3 PF04981.13 KRZ99998.1 - 1.8e-83 279.8 2.0 3.4e-83 278.8 2.0 1.5 1 0 0 1 1 1 1 NMD3 family VPS11_C PF12451.8 KRZ99998.1 - 0.038 14.2 3.7 0.085 13.1 3.7 1.6 1 0 0 1 1 1 0 Vacuolar protein sorting protein 11 C terminal DZR PF12773.7 KRZ99998.1 - 0.46 10.6 5.7 21 5.2 5.7 2.7 1 1 0 1 1 1 0 Double zinc ribbon HypA PF01155.19 KRZ99998.1 - 1.3 9.1 6.3 4 7.5 0.0 2.5 2 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA FYVE PF01363.21 KRZ99998.1 - 3.9 7.7 6.3 0.73 10.0 0.1 2.5 3 0 0 3 3 3 0 FYVE zinc finger Bromodomain PF00439.25 KRZ99999.1 - 1.5e-24 85.8 0.4 3.4e-24 84.7 0.4 1.6 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 KRZ99999.1 - 3.8e-09 36.8 0.0 6.8e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KRZ99999.1 - 5.8e-07 29.5 0.0 1.1e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KRZ99999.1 - 0.00039 20.8 0.1 0.00071 20.0 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Vfa1 PF08432.10 KRZ99999.1 - 1.3 9.3 6.7 2.3 8.5 6.7 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CDC45 PF02724.14 KRZ99999.1 - 2.1 6.5 10.0 2.8 6.1 10.0 1.1 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.11 KRZ99999.1 - 4 5.9 9.5 6.2 5.2 9.5 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF2457 PF10446.9 KRZ99999.1 - 4.1 6.4 17.2 5.7 6.0 17.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Sigma70_ner PF04546.13 KRZ99999.1 - 4.3 7.2 13.2 8.7 6.2 13.2 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region Glucosamine_iso PF01182.20 KSA00001.1 - 7.1e-64 215.8 0.0 8e-64 215.6 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase CPDase PF07823.11 KSA00002.1 - 8.2e-46 156.2 0.6 9.9e-45 152.7 0.6 1.9 1 1 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.6 KSA00002.1 - 0.045 13.7 0.0 3.3 7.6 0.0 2.3 2 0 0 2 2 2 0 2'-5' RNA ligase superfamily NmrA PF05368.13 KSA00003.1 - 1.9e-10 40.7 0.0 2.4e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Bacillus_HBL PF05791.11 KSA00003.1 - 0.094 12.5 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Taeniidae_ag PF05596.11 KSA00003.1 - 0.14 12.1 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 Taeniidae antigen ADH_N PF08240.12 KSA00004.1 - 0.012 15.5 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Brix PF04427.18 KSA00005.1 - 4.7e-31 108.4 1.5 6.1e-31 108.0 1.5 1.1 1 0 0 1 1 1 1 Brix domain TrkH PF02386.16 KSA00006.1 - 8.8e-168 558.8 6.8 1.1e-166 555.2 2.7 2.1 2 0 0 2 2 2 2 Cation transport protein Nop14 PF04147.12 KSA00006.1 - 0.0017 16.7 24.8 0.0017 16.7 24.8 1.8 2 0 0 2 2 2 1 Nop14-like family RNA_pol_3_Rpc31 PF11705.8 KSA00006.1 - 5.4 7.2 37.2 1.2 9.3 28.6 2.6 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 MFS_1 PF07690.16 KSA00007.1 - 8.1e-44 150.0 25.5 1.2e-43 149.4 25.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KSA00007.1 - 2.2e-07 30.1 15.1 2.2e-07 30.1 15.1 3.0 2 1 1 3 3 3 2 Sugar (and other) transporter CPSase_L_D2 PF02786.17 KSA00008.1 - 2.7e-116 386.5 0.9 3.1e-85 285.0 0.1 2.4 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 KSA00008.1 - 1.2e-47 160.9 0.0 3.3e-47 159.5 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain OTCace_N PF02729.21 KSA00008.1 - 6.1e-47 159.4 0.0 1.7e-46 157.9 0.0 1.8 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain GATase PF00117.28 KSA00008.1 - 1.2e-45 155.7 0.0 3.2e-45 154.2 0.0 1.8 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_L_D3 PF02787.19 KSA00008.1 - 1.4e-38 132.0 0.0 3.5e-38 130.7 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 KSA00008.1 - 8.5e-29 100.6 0.7 1.5e-27 96.6 0.1 2.9 3 0 0 3 3 3 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGS PF02142.22 KSA00008.1 - 1.7e-20 73.0 0.0 7.5e-20 70.9 0.0 2.3 1 0 0 1 1 1 1 MGS-like domain Dala_Dala_lig_C PF07478.13 KSA00008.1 - 1.7e-18 66.9 1.9 1.3e-10 41.2 0.1 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KSA00008.1 - 1e-14 54.5 0.1 1.6e-07 31.1 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 KSA00008.1 - 3.8e-10 39.6 0.0 6.6e-05 22.7 0.0 2.8 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 KSA00008.1 - 4.6e-07 30.0 0.5 0.015 15.3 0.1 3.1 3 0 0 3 3 3 2 ATP-grasp domain Peptidase_C26 PF07722.13 KSA00008.1 - 1.7e-05 24.7 0.1 0.0028 17.4 0.1 2.9 1 1 0 1 1 1 1 Peptidase C26 GARS_A PF01071.19 KSA00008.1 - 0.0011 18.7 0.4 1.2 8.8 0.0 2.8 2 1 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain DJ-1_PfpI PF01965.24 KSA00008.1 - 0.0015 18.3 0.1 0.29 10.9 0.0 3.7 4 0 0 4 4 4 1 DJ-1/PfpI family zf-H2C2 PF09337.10 KSA00009.1 - 4.7e-14 52.3 1.2 8.3e-14 51.5 1.2 1.4 1 0 0 1 1 1 1 H2C2 zinc finger Integrase_H2C2 PF17921.1 KSA00009.1 - 6.2e-10 39.0 0.5 1.7e-09 37.7 0.5 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Acetyltransf_1 PF00583.25 KSA00009.1 - 5.8e-08 33.0 0.0 1.2e-07 32.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KSA00009.1 - 0.0029 18.0 0.0 0.017 15.5 0.0 2.3 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KSA00009.1 - 0.019 15.1 0.0 0.049 13.8 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain YfdX PF10938.8 KSA00009.1 - 0.041 13.8 2.0 0.085 12.8 0.6 2.0 2 0 0 2 2 2 0 YfdX protein Acetyltransf_10 PF13673.7 KSA00009.1 - 0.051 13.5 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KSA00009.1 - 0.11 13.2 0.0 0.28 11.8 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KSA00010.1 - 0.00024 21.3 0.1 0.00059 20.1 0.1 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 KSA00010.1 - 0.012 16.3 0.0 0.032 14.9 0.0 1.8 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KSA00010.1 - 0.041 14.3 0.1 0.16 12.4 0.1 2.1 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Reovirus_cap PF00979.17 KSA00010.1 - 0.2 10.8 0.0 0.27 10.3 0.0 1.1 1 0 0 1 1 1 0 Reovirus outer capsid protein, Sigma 3 Sds3 PF08598.11 KSA00011.1 - 1.8e-63 214.5 18.1 3.4e-63 213.6 18.1 1.4 1 1 0 1 1 1 1 Sds3-like zf-C4H2 PF10146.9 KSA00011.1 - 0.0018 18.6 2.6 0.0022 18.3 2.6 1.2 1 0 0 1 1 1 1 Zinc finger-containing protein ATP-synt_F PF01990.17 KSA00011.1 - 0.068 13.5 0.1 0.18 12.1 0.2 1.7 2 0 0 2 2 2 0 ATP synthase (F/14-kDa) subunit Op_neuropeptide PF08035.11 KSA00011.1 - 0.14 12.0 0.2 0.35 10.7 0.2 1.7 1 0 0 1 1 1 0 Opioids neuropeptide STAT_int PF02865.17 KSA00011.1 - 0.32 11.5 6.6 0.16 12.5 2.8 2.1 2 0 0 2 2 2 0 STAT protein, protein interaction domain IZUMO PF15005.6 KSA00011.1 - 1.6 9.3 6.6 2.8 8.5 6.6 1.4 1 0 0 1 1 1 0 Izumo sperm-egg fusion, Ig domain-associated Glyco_transf_15 PF01793.16 KSA00012.1 - 2.4e-93 312.9 17.5 6e-61 206.5 9.1 2.2 1 1 1 2 2 2 2 Glycolipid 2-alpha-mannosyltransferase PBP1_TM PF14812.6 KSA00012.1 - 0.043 14.2 0.4 0.16 12.4 0.4 1.9 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4093 PF13331.6 KSA00012.1 - 0.11 13.0 0.1 0.26 11.7 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4093) CENP-T_C PF15511.6 KSA00013.1 - 2.4e-09 37.3 0.1 2.9e-09 37.0 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 KSA00013.1 - 3e-05 24.1 0.1 4.2e-05 23.6 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KSA00013.1 - 5.3e-05 23.4 0.0 9.4e-05 22.6 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 KSA00013.1 - 7.4e-05 23.1 0.1 9.7e-05 22.7 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein Histone PF00125.24 KSA00013.1 - 0.0001 22.7 0.1 0.00012 22.4 0.1 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KSA00013.1 - 0.0043 17.1 0.0 0.0051 16.9 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KSA00013.1 - 0.009 16.0 0.0 0.01 15.8 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated UPF0137 PF03677.13 KSA00013.1 - 0.021 14.6 0.2 0.026 14.3 0.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) TFIID_20kDa PF03847.13 KSA00013.1 - 0.081 13.4 0.0 0.13 12.7 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A BDV_G PF06208.11 KSA00013.1 - 0.14 11.3 0.0 0.16 11.1 0.0 1.0 1 0 0 1 1 1 0 Borna disease virus G protein Histone PF00125.24 KSA00014.1 - 5.3e-51 172.4 2.8 5.9e-51 172.2 2.8 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KSA00014.1 - 3.8e-06 27.2 0.0 5.8e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KSA00014.1 - 5e-05 23.4 0.5 8e-05 22.7 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 KSA00014.1 - 5.6e-05 23.7 1.3 6.9e-05 23.5 1.3 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 KSA00014.1 - 0.0052 17.0 0.6 0.0079 16.5 0.1 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KSA00014.1 - 0.023 14.8 0.1 0.039 14.0 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Aim19 PF10315.9 KSA00015.1 - 2.7e-43 146.9 4.0 3.1e-43 146.7 4.0 1.0 1 0 0 1 1 1 1 Altered inheritance of mitochondria protein 19 Y_phosphatase2 PF03162.13 KSA00016.1 - 1.6e-59 200.2 0.0 2.4e-59 199.6 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 KSA00016.1 - 7e-07 29.5 0.0 9.3e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 KSA00016.1 - 0.0016 18.1 0.0 0.0025 17.4 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KSA00016.1 - 0.0025 17.6 0.0 0.005 16.6 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain UTP25 PF06862.12 KSA00017.1 - 6.1e-208 691.3 15.4 8.7e-208 690.8 15.4 1.2 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Helicase_C PF00271.31 KSA00017.1 - 0.0031 17.8 0.2 0.076 13.4 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ICE2 PF08426.10 KSA00018.1 - 5.4e-88 295.8 2.5 6.5e-88 295.6 2.5 1.1 1 0 0 1 1 1 1 ICE2 IucA_IucC PF04183.12 KSA00018.1 - 0.071 12.7 0.0 0.09 12.3 0.0 1.2 1 0 0 1 1 1 0 IucA / IucC family RITA PF17066.5 KSA00018.1 - 0.13 11.8 4.6 0.19 11.3 4.6 1.1 1 0 0 1 1 1 0 RBPJ-interacting and tubulin associated protein DUF1776 PF08643.10 KSA00019.1 - 2.7e-112 375.0 0.8 3.4e-112 374.7 0.8 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Cpn10 PF00166.21 KSA00020.1 - 2.9e-29 101.0 0.0 3.2e-29 100.8 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Ras PF00071.22 KSA00021.1 - 5.8e-54 182.1 0.1 6.9e-54 181.8 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KSA00021.1 - 3e-37 127.5 0.0 4.5e-37 126.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KSA00021.1 - 3e-18 65.9 0.0 3.7e-18 65.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KSA00021.1 - 3.6e-08 33.1 0.0 4.4e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KSA00021.1 - 8.9e-06 25.8 0.0 1.3e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KSA00021.1 - 3.3e-05 23.5 0.1 4.5e-05 23.1 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KSA00021.1 - 0.00011 22.1 0.3 0.18 11.7 0.1 2.2 2 0 0 2 2 2 2 RsgA GTPase G-alpha PF00503.20 KSA00021.1 - 0.014 14.5 0.2 0.069 12.3 0.2 2.2 1 1 0 1 1 1 0 G-protein alpha subunit TniB PF05621.11 KSA00021.1 - 0.02 14.3 0.0 0.036 13.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AAA_16 PF13191.6 KSA00021.1 - 0.023 15.1 0.0 0.038 14.4 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KSA00021.1 - 0.031 14.5 0.0 4 7.7 0.0 2.2 1 1 0 2 2 2 0 AAA domain Septin PF00735.18 KSA00021.1 - 0.084 12.1 0.1 0.22 10.8 0.0 1.6 2 0 0 2 2 2 0 Septin SRPRB PF09439.10 KSA00021.1 - 0.094 12.1 0.0 0.15 11.5 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Pkinase PF00069.25 KSA00022.1 - 1.5e-10 40.9 0.2 4.1e-10 39.5 0.2 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KSA00022.1 - 3.1e-06 26.7 0.3 1.9e-05 24.1 0.1 2.2 1 1 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KSA00022.1 - 7.5e-05 22.8 0.0 0.00013 22.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KSA00022.1 - 0.00022 20.9 0.1 0.00061 19.4 0.1 1.8 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 KSA00022.1 - 0.0027 17.3 0.1 0.0057 16.3 0.1 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 KSA00022.1 - 0.0034 16.8 0.1 0.0071 15.7 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KSA00022.1 - 0.048 12.4 0.1 0.099 11.4 0.1 1.4 1 0 0 1 1 1 0 Fungal protein kinase Ribosomal_L4 PF00573.22 KSA00023.1 - 2e-41 141.8 1.6 3.6e-41 141.0 1.6 1.4 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 KSA00023.1 - 1.9e-30 104.7 1.8 8.3e-30 102.7 0.8 2.2 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain CAP PF00188.26 KSA00024.1 - 6.4e-21 75.5 4.9 6.4e-21 75.5 4.9 2.3 2 1 0 2 2 2 1 Cysteine-rich secretory protein family TFIIA PF03153.13 KSA00024.1 - 0.0046 17.0 31.6 0.0066 16.5 31.6 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.9 KSA00024.1 - 0.043 12.4 22.4 0.053 12.1 22.4 1.1 1 0 0 1 1 1 0 Macoilin family PAP1 PF08601.10 KSA00024.1 - 0.33 10.6 35.5 0.48 10.1 35.5 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 Hamartin PF04388.12 KSA00024.1 - 0.67 8.6 30.1 0.92 8.1 30.1 1.2 1 0 0 1 1 1 0 Hamartin protein PAT1 PF09770.9 KSA00024.1 - 1.1 7.4 29.0 1.3 7.2 29.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF966 PF06136.13 KSA00024.1 - 2 8.0 28.4 2.7 7.6 28.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) PA26 PF04636.13 KSA00024.1 - 2.7 6.8 11.6 3.8 6.3 11.6 1.3 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) GREB1 PF15782.5 KSA00024.1 - 3.5 4.6 29.6 4.2 4.3 29.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Lin-8 PF03353.15 KSA00024.1 - 3.6 7.0 27.0 5.2 6.5 27.0 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Utp14 PF04615.13 KSA00024.1 - 8.7 4.8 28.2 11 4.5 28.2 1.0 1 0 0 1 1 1 0 Utp14 protein DUF3808 PF10300.9 KSA00025.1 - 6.9e-126 420.8 0.6 9.8e-126 420.3 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_2 PF07719.17 KSA00025.1 - 0.046 13.8 1.6 4.3 7.7 0.2 3.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 KSA00025.1 - 0.075 13.7 0.2 10 6.9 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 KSA00025.1 - 0.14 12.4 1.1 3.6 7.8 0.2 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat UNC-50 PF05216.13 KSA00026.1 - 1.9e-94 315.3 17.1 2.3e-94 315.1 17.1 1.1 1 0 0 1 1 1 1 UNC-50 family FeoB_C PF07664.12 KSA00026.1 - 0.48 10.2 4.5 8.7 6.1 1.2 3.0 2 0 0 2 2 2 0 Ferrous iron transport protein B C terminus IBR PF01485.21 KSA00028.1 - 1.3e-20 73.4 45.6 1.1e-10 41.6 4.9 4.1 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 KSA00028.1 - 0.0012 18.7 11.5 0.0012 18.7 11.5 5.2 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KSA00028.1 - 0.0084 16.1 11.6 0.0084 16.1 11.6 4.0 2 1 1 3 3 3 1 zinc-RING finger domain Cul7 PF11515.8 KSA00028.1 - 0.0088 16.3 0.2 0.05 13.9 0.0 2.2 2 0 0 2 2 2 1 Mouse development and cellular proliferation protein Cullin-7 zf-C3HC4_2 PF13923.6 KSA00028.1 - 0.023 14.5 5.7 0.023 14.5 5.7 4.8 3 1 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) DNA_ligase_ZBD PF03119.16 KSA00028.1 - 6.5 6.9 13.4 3.9 7.6 2.0 3.1 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain SDA1 PF05285.12 KSA00029.1 - 5.4 6.3 42.3 0.16 11.4 33.2 2.4 2 0 0 2 2 2 0 SDA1 Pam16 PF03656.13 KSA00030.1 - 9.4e-32 109.7 0.2 1.2e-31 109.4 0.2 1.1 1 0 0 1 1 1 1 Pam16 PHD PF00628.29 KSA00031.1 - 2.8e-07 30.3 11.0 5.8e-07 29.3 11.0 1.6 1 0 0 1 1 1 1 PHD-finger LRR_8 PF13855.6 KSA00032.1 - 8.6e-09 35.0 20.9 2.6e-06 27.1 2.1 4.7 4 1 1 5 5 5 2 Leucine rich repeat LRR_4 PF12799.7 KSA00032.1 - 1.9e-05 24.9 6.5 0.00034 21.0 1.3 5.1 5 1 0 5 5 5 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KSA00032.1 - 0.0003 20.6 14.0 0.2 11.8 0.0 5.9 5 0 0 5 5 5 3 Leucine Rich repeat F-box PF00646.33 KSA00032.1 - 0.0033 17.3 0.1 0.083 12.8 0.1 3.0 2 1 0 2 2 2 1 F-box domain FNIP PF05725.12 KSA00032.1 - 0.0062 16.7 11.5 0.13 12.5 0.2 4.0 2 1 1 3 3 3 2 FNIP Repeat CAAP1 PF15335.6 KSA00032.1 - 0.033 14.7 1.0 6.3 7.4 0.1 3.6 3 0 0 3 3 3 0 Caspase activity and apoptosis inhibitor 1 MitMem_reg PF13012.6 KSA00032.1 - 0.047 14.1 0.2 0.18 12.2 0.0 1.9 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function F-box-like PF12937.7 KSA00032.1 - 0.054 13.4 0.1 0.21 11.5 0.1 2.0 1 0 0 1 1 1 0 F-box-like ABC_membrane PF00664.23 KSA00033.1 - 7.9e-70 235.6 34.0 1.8e-39 136.1 17.9 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KSA00033.1 - 4e-46 156.9 8.4 1.2e-28 100.3 0.0 3.9 3 1 0 3 3 2 2 ABC transporter AAA_29 PF13555.6 KSA00033.1 - 2.2e-07 30.5 0.6 0.0034 17.1 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 KSA00033.1 - 4e-05 23.1 17.0 0.0005 19.6 0.7 4.6 4 1 0 4 4 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KSA00033.1 - 0.00023 21.1 17.6 0.034 14.0 0.0 5.5 6 1 1 7 7 7 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 KSA00033.1 - 0.00026 21.1 1.1 0.26 11.4 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_18 PF13238.6 KSA00033.1 - 0.001 19.7 0.0 2.8 8.5 0.0 3.5 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KSA00033.1 - 0.001 19.0 1.4 1.6 8.6 0.7 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 KSA00033.1 - 0.0011 19.5 17.4 0.022 15.2 4.0 4.0 3 1 1 4 4 4 2 AAA domain DUF815 PF05673.13 KSA00033.1 - 0.013 14.6 0.4 0.31 10.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_16 PF13191.6 KSA00033.1 - 0.022 15.2 1.4 2.4 8.5 0.1 2.7 2 1 0 2 2 2 0 AAA ATPase domain MeaB PF03308.16 KSA00033.1 - 0.038 13.0 0.1 7.2 5.5 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 KSA00033.1 - 0.057 13.1 0.6 8.8 6.0 0.0 2.6 3 0 0 3 3 2 0 AAA domain cobW PF02492.19 KSA00033.1 - 0.083 12.5 0.3 1.8 8.1 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain T2SSE PF00437.20 KSA00033.1 - 0.084 11.9 0.3 0.41 9.7 0.1 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein ATP_bind_1 PF03029.17 KSA00033.1 - 0.093 12.5 1.6 6.5 6.5 0.2 3.3 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 KSA00033.1 - 0.18 12.1 5.4 9.8 6.4 0.2 3.4 2 1 0 2 2 2 0 AAA domain DUF87 PF01935.17 KSA00033.1 - 0.66 10.0 0.0 0.66 10.0 0.0 3.5 3 0 0 3 3 3 0 Helicase HerA, central domain Sensor PF13796.6 KSA00033.1 - 0.98 9.4 0.0 0.98 9.4 0.0 3.3 3 1 0 3 3 2 0 Putative sensor DUF2721 PF11026.8 KSA00033.1 - 2.5 8.0 10.8 0.2 11.5 0.2 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) ADH_zinc_N PF00107.26 KSA00034.1 - 2.9e-11 43.4 0.1 6.3e-11 42.4 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KSA00034.1 - 3.8e-06 26.7 0.0 6.7e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Asp_decarbox PF02261.16 KSA00034.1 - 0.059 13.3 0.1 0.45 10.5 0.0 2.1 2 0 0 2 2 2 0 Aspartate decarboxylase Bac_luciferase PF00296.20 KSA00035.1 - 3.2e-53 181.2 0.0 4.2e-53 180.8 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Zip PF02535.22 KSA00036.1 - 3.4e-65 220.5 1.5 4.9e-65 219.9 1.5 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter RseC_MucC PF04246.12 KSA00036.1 - 0.2 11.6 0.5 3 7.8 0.0 2.8 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC HalX PF08663.10 KSA00036.1 - 0.95 9.8 2.5 1.6 9.1 2.5 1.2 1 0 0 1 1 1 0 HalX domain Per1 PF04080.13 KSA00037.1 - 3.8e-26 92.4 1.2 4.3e-26 92.2 1.2 1.0 1 0 0 1 1 1 1 Per1-like family TP_methylase PF00590.20 KSA00038.1 - 6.7e-27 94.8 0.0 1.1e-26 94.1 0.0 1.3 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases MHC_I_2 PF14586.6 KSA00039.1 - 0.06 13.2 0.2 0.1 12.5 0.2 1.3 1 0 0 1 1 1 0 Class I Histocompatibility antigen, NKG2D ligand, domains 1 and 2 Tox-HNH-HHH PF15637.6 KSA00039.1 - 0.18 12.0 2.0 0.28 11.4 0.4 2.0 2 0 0 2 2 2 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif V-ATPase_G PF03179.15 KSA00039.1 - 4.4 7.9 9.6 16 6.1 0.2 2.8 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit polyprenyl_synt PF00348.17 KSA00040.1 - 8e-48 162.7 0.0 1.1e-47 162.3 0.0 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase DER1 PF04511.15 KSA00041.1 - 4e-29 101.9 10.4 6.6e-29 101.2 10.4 1.4 1 0 0 1 1 1 1 Der1-like family VPS9 PF02204.18 KSA00042.1 - 1.3e-12 47.9 4.8 1.5e-11 44.4 4.8 2.6 1 1 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain MetOD2 PF18548.1 KSA00042.1 - 0.28 11.3 0.1 0.28 11.3 0.1 3.6 5 0 0 5 5 5 0 Metanogen output domain 2 CRISPR_Cas9_WED PF18061.1 KSA00043.1 - 0.019 15.0 1.2 0.019 15.0 1.2 2.8 1 1 2 3 3 3 0 CRISPR-Cas9 WED domain LRR_4 PF12799.7 KSA00044.1 - 9.3e-06 25.9 18.3 0.082 13.4 2.9 4.8 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KSA00044.1 - 0.00014 21.5 21.1 0.0035 17.1 4.8 4.4 3 1 1 4 4 4 3 Leucine rich repeat LRR_1 PF00560.33 KSA00044.1 - 0.33 11.6 16.8 7.4 7.6 0.3 5.9 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_6 PF13516.6 KSA00044.1 - 9.7 6.5 17.1 24 5.3 0.4 5.2 6 0 0 6 6 6 0 Leucine Rich repeat ABC_membrane PF00664.23 KSA00045.1 - 7.6e-57 193.0 0.5 1e-56 192.6 0.5 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KSA00045.1 - 2e-35 122.3 0.0 4.6e-35 121.1 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KSA00045.1 - 1.1e-07 31.6 2.8 2.4e-05 23.9 0.3 2.8 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KSA00045.1 - 1.8e-05 25.0 0.6 0.00029 21.1 0.6 2.4 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KSA00045.1 - 0.00068 19.6 0.0 0.017 15.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_15 PF13175.6 KSA00045.1 - 0.0013 18.5 1.2 0.0055 16.5 0.1 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_7 PF12775.7 KSA00045.1 - 0.0017 17.9 0.0 0.0035 16.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA PF00004.29 KSA00045.1 - 0.0033 17.8 1.0 0.09 13.2 1.0 2.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 KSA00045.1 - 0.0039 16.6 1.5 0.076 12.4 0.1 2.7 3 0 0 3 3 3 1 Bacterial TniB protein AAA_16 PF13191.6 KSA00045.1 - 0.0051 17.2 0.0 0.018 15.5 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 KSA00045.1 - 0.024 14.4 0.1 0.06 13.1 0.1 1.7 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KSA00045.1 - 0.06 13.3 0.1 0.14 12.0 0.1 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 KSA00045.1 - 0.065 13.0 0.4 0.15 11.8 0.4 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.6 KSA00045.1 - 0.078 13.1 0.0 0.19 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 KSA00045.1 - 0.095 12.9 1.0 0.9 9.8 1.0 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit DEAD PF00270.29 KSA00045.1 - 0.11 12.3 0.3 2.7 7.7 0.3 2.5 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_18 PF13238.6 KSA00045.1 - 0.12 12.9 0.0 0.6 10.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KSA00045.1 - 0.12 11.9 0.0 6.2 6.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KSA00045.1 - 0.17 11.6 0.6 2.6 7.8 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 KSA00045.1 - 0.17 11.2 0.0 0.4 10.0 0.0 1.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Glyco_transf_28 PF03033.20 KSA00046.1 - 8e-32 110.2 0.0 2.1e-31 108.8 0.0 1.8 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.20 KSA00046.1 - 1.4e-21 76.5 1.3 4.2e-18 65.3 0.0 3.2 3 0 0 3 3 3 2 GRAM domain UDPGT PF00201.18 KSA00046.1 - 9.5e-08 31.3 0.0 2e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH PF00169.29 KSA00046.1 - 0.001 19.5 0.7 0.0053 17.3 0.2 2.6 2 1 0 2 2 2 1 PH domain Abhydrolase_1 PF00561.20 KSA00047.1 - 1.6e-48 165.6 0.0 2.4e-48 165.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KSA00047.1 - 0.0015 19.2 0.0 0.0021 18.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KSA00047.1 - 0.0076 15.5 0.1 0.062 12.6 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Esterase PF00756.20 KSA00047.1 - 0.015 14.9 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Ribonuc_P_40 PF08584.11 KSA00048.1 - 0.0014 18.0 0.1 0.0028 17.0 0.0 1.6 2 0 0 2 2 2 1 Ribonuclease P 40kDa (Rpp40) subunit DinI PF06183.13 KSA00048.1 - 0.13 12.7 0.1 0.73 10.2 0.0 2.3 3 0 0 3 3 3 0 DinI-like family Zn_clus PF00172.18 KSA00049.1 - 2.3e-09 37.2 7.8 4.4e-09 36.3 7.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KSA00049.1 - 4.2e-09 35.8 0.7 4.2e-09 35.8 0.7 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain WD40 PF00400.32 KSA00050.1 - 9.1e-17 61.1 11.3 0.021 15.7 0.1 6.4 6 1 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KSA00050.1 - 2.1e-07 31.1 0.1 4.3 7.7 0.0 5.1 4 1 1 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KSA00050.1 - 0.023 13.4 0.3 0.044 12.4 0.3 1.4 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Thioredoxin PF00085.20 KSA00051.1 - 3.5e-51 171.5 0.5 4.1e-24 84.5 0.0 3.8 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.6 KSA00051.1 - 1.9e-29 102.9 1.0 1e-25 90.7 3.8 2.7 2 1 1 3 3 3 2 Thioredoxin-like domain OST3_OST6 PF04756.13 KSA00051.1 - 4.7e-09 36.0 0.0 0.0017 17.7 0.0 3.6 3 1 1 4 4 4 2 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 KSA00051.1 - 3.3e-08 34.0 0.0 0.0036 17.7 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KSA00051.1 - 4.2e-06 26.9 0.0 0.0036 17.5 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.6 KSA00051.1 - 8e-05 22.9 0.6 0.86 10.0 0.0 3.9 4 1 1 5 5 5 2 Thioredoxin-like AhpC-TSA PF00578.21 KSA00051.1 - 0.00019 21.3 0.3 1.7 8.6 0.0 3.6 3 1 0 3 3 3 2 AhpC/TSA family Redoxin PF08534.10 KSA00051.1 - 0.0011 18.7 0.3 0.031 14.0 0.0 2.8 3 0 0 3 3 3 1 Redoxin Thioredoxin_9 PF14595.6 KSA00051.1 - 0.047 13.5 0.1 5.7 6.7 0.0 2.4 2 0 0 2 2 2 0 Thioredoxin Thioredoxin_3 PF13192.6 KSA00051.1 - 0.051 13.6 0.1 20 5.3 0.0 2.8 2 0 0 2 2 2 0 Thioredoxin domain Oxidored_q3 PF00499.20 KSA00052.1 - 0.014 15.1 1.1 0.018 14.8 1.0 1.3 1 1 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 LRR_9 PF14580.6 KSA00054.1 - 3.9e-40 137.2 4.5 4.2e-40 137.1 4.5 1.0 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 KSA00054.1 - 4.9e-07 30.0 19.4 0.00049 20.4 3.3 3.4 3 1 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KSA00054.1 - 7.5e-07 28.8 17.5 8.3e-06 25.5 7.7 2.8 2 1 1 3 3 3 2 Leucine rich repeat UPF0183 PF03676.14 KSA00055.1 - 9.5e-55 186.5 8.5 6.1e-54 183.8 8.5 2.0 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0183) Retrotran_gag_2 PF14223.6 KSA00055.1 - 0.031 13.9 0.5 0.22 11.2 0.1 2.2 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type Ammonium_transp PF00909.21 KSA00056.1 - 3.4e-121 404.7 27.8 3.9e-121 404.5 27.8 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family nec1 PF10379.9 KSA00056.1 - 0.31 10.5 1.2 0.54 9.7 0.6 1.7 2 0 0 2 2 2 0 Virulence protein nec1 TssN PF17555.2 KSA00056.1 - 3.4 7.0 9.3 0.96 8.8 6.5 1.5 2 0 0 2 2 2 0 Type VI secretion system, TssN muHD PF10291.9 KSA00057.1 - 9.2e-50 169.5 1.1 9.2e-50 169.5 1.1 2.5 2 0 0 2 2 2 1 Muniscin C-terminal mu homology domain Glyco_hydro_31 PF01055.26 KSA00058.1 - 5e-159 530.2 2.5 6.4e-159 529.8 2.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 KSA00058.1 - 9.3e-26 90.3 0.1 2e-25 89.2 0.1 1.6 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Rotavirus_VP7 PF05868.11 KSA00058.1 - 0.013 14.9 0.1 0.031 13.7 0.1 1.5 1 0 0 1 1 1 0 Rotavirus major outer capsid protein VP7 p450 PF00067.22 KSA00059.1 - 2.8e-51 174.7 0.1 4.1e-51 174.2 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 Vac7 PF12751.7 KSA00060.1 - 1.1e-24 87.7 37.9 5.6e-16 59.0 0.0 4.6 2 1 2 4 4 4 2 Vacuolar segregation subunit 7 6PF2K PF01591.18 KSA00061.1 - 5.1e-77 258.1 0.5 2.2e-76 256.1 0.0 2.3 2 1 0 2 2 2 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KSA00061.1 - 1.4e-29 103.2 0.0 1.5e-23 83.5 0.0 2.4 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) KTI12 PF08433.10 KSA00061.1 - 0.022 14.2 0.3 0.13 11.7 0.0 2.3 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_33 PF13671.6 KSA00061.1 - 0.022 14.9 0.2 0.11 12.6 0.2 2.1 1 1 0 1 1 1 0 AAA domain Methyltransf_16 PF10294.9 KSA00062.1 - 3.8e-05 23.5 0.0 0.0009 19.0 0.0 2.3 2 0 0 2 2 2 1 Lysine methyltransferase Methyltransf_23 PF13489.6 KSA00062.1 - 0.029 14.2 0.0 0.049 13.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain COX4 PF02936.14 KSA00063.1 - 2.6e-35 121.4 0.1 3.2e-35 121.2 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF3731 PF12531.8 KSA00063.1 - 0.043 13.6 0.1 0.054 13.3 0.1 1.1 1 0 0 1 1 1 0 DNA-K related protein Ntox17 PF15524.6 KSA00063.1 - 0.12 12.7 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 Novel toxin 17 Pkinase PF00069.25 KSA00064.1 - 2.3e-45 155.0 1.7 2.3e-44 151.8 1.7 2.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KSA00064.1 - 1e-25 90.5 0.0 4.5e-25 88.4 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase GATA PF00320.27 KSA00065.1 - 4.9e-28 96.4 14.4 2.5e-15 55.8 5.4 3.8 4 0 0 4 4 4 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 KSA00065.1 - 2.3e-05 23.8 9.0 0.002 17.6 0.1 3.1 3 0 0 3 3 3 2 TFIIB zinc-binding ArfGap PF01412.18 KSA00065.1 - 6.5e-05 23.0 12.9 0.014 15.4 2.8 3.2 3 0 0 3 3 3 2 Putative GTPase activating protein for Arf TDP43_N PF18694.1 KSA00065.1 - 0.004 17.0 0.1 0.43 10.5 0.1 3.0 3 0 0 3 3 3 1 Transactive response DNA-binding protein N-terminal domain SPX PF03105.19 KSA00065.1 - 0.0055 16.7 6.5 0.0055 16.7 6.5 2.1 2 1 0 2 2 2 1 SPX domain TFIIA PF03153.13 KSA00065.1 - 0.0075 16.3 12.6 0.0075 16.3 12.6 2.9 3 0 0 3 3 3 2 Transcription factor IIA, alpha/beta subunit DZR PF12773.7 KSA00065.1 - 0.013 15.5 13.0 0.55 10.3 0.2 3.9 3 1 1 4 4 4 0 Double zinc ribbon OrfB_Zn_ribbon PF07282.11 KSA00065.1 - 0.032 14.1 0.3 0.032 14.1 0.3 3.2 4 0 0 4 4 3 0 Putative transposase DNA-binding domain eIF-5_eIF-2B PF01873.17 KSA00065.1 - 0.05 13.5 4.0 5.7 6.9 0.5 2.9 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Zn-ribbon_8 PF09723.10 KSA00065.1 - 0.12 12.5 11.6 1.5 9.0 0.1 3.7 4 0 0 4 4 3 0 Zinc ribbon domain zf-RRN7 PF11781.8 KSA00065.1 - 0.46 10.2 11.9 0.38 10.5 0.7 3.3 3 0 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 SelP_N PF04592.14 KSA00065.1 - 1.4 8.3 22.8 4.7 6.6 22.8 1.9 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Auto_anti-p27 PF06677.12 KSA00065.1 - 1.5 9.1 13.8 0.4 10.9 0.6 3.4 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Zip PF02535.22 KSA00065.1 - 2.1 7.5 8.1 0.076 12.2 1.9 1.9 2 0 0 2 2 2 0 ZIP Zinc transporter DUF4045 PF13254.6 KSA00065.1 - 3.6 7.1 25.6 1.3 8.6 3.9 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4045) zf-ribbon_3 PF13248.6 KSA00065.1 - 9.2 5.8 18.3 11 5.6 0.2 5.2 5 0 0 5 5 5 0 zinc-ribbon domain Mito_carr PF00153.27 KSA00066.1 - 1.5e-54 181.9 2.0 3.3e-18 65.4 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Fer4 PF00037.27 KSA00067.1 - 1.2e-13 50.2 17.1 5.2e-08 32.4 4.2 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 KSA00067.1 - 1.8e-12 47.6 10.2 3.9e-12 46.5 10.2 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 KSA00067.1 - 8.1e-11 42.7 10.2 1.4e-05 25.9 1.2 2.4 1 1 1 2 2 2 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 KSA00067.1 - 6.6e-10 39.0 20.8 1.4e-06 28.3 12.0 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 KSA00067.1 - 5.6e-09 36.0 21.3 1.3e-07 31.7 10.8 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 KSA00067.1 - 1.1e-08 35.4 5.7 4.4e-05 23.8 0.8 2.4 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 KSA00067.1 - 1.4e-08 34.8 32.6 1.1e-05 25.4 12.7 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_17 PF13534.6 KSA00067.1 - 5.5e-07 30.0 5.4 0.0054 17.2 1.0 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 KSA00067.1 - 1.5e-06 28.2 11.1 0.00029 21.1 1.8 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 KSA00067.1 - 1.9e-06 27.6 11.9 0.0051 16.8 1.8 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.7 KSA00067.1 - 2e-06 27.6 18.1 0.00038 20.4 5.4 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain c-SKI_SMAD_bind PF08782.10 KSA00067.1 - 0.037 14.3 6.1 0.4 11.0 0.2 2.3 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Fer4_3 PF12798.7 KSA00067.1 - 0.089 13.8 15.4 0.22 12.6 3.2 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_18 PF13746.6 KSA00067.1 - 0.098 12.9 9.9 9.9 6.4 9.4 2.4 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_13 PF13370.6 KSA00067.1 - 0.11 13.0 16.1 0.72 10.4 4.3 2.9 2 1 1 3 3 3 0 4Fe-4S single cluster domain of Ferredoxin I ETF_QO PF05187.13 KSA00067.1 - 0.16 12.1 5.9 0.5 10.5 0.5 2.3 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_22 PF17179.4 KSA00067.1 - 0.35 11.8 11.5 0.83 10.5 1.2 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain DSPc PF00782.20 KSA00068.1 - 3.8e-32 110.9 0.2 3.4e-31 107.8 0.2 2.2 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KSA00068.1 - 0.00021 21.0 0.0 0.00031 20.4 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 KSA00068.1 - 0.0018 18.5 0.0 0.0035 17.6 0.0 1.4 1 0 0 1 1 1 1 Rit1 DUSP-like domain HPIP PF15226.6 KSA00068.1 - 0.099 13.1 1.1 6.1 7.3 0.6 2.5 3 0 0 3 3 3 0 HCF-1 beta-propeller-interacting protein family Ank_2 PF12796.7 KSA00069.1 - 9.8e-49 163.9 6.3 2e-16 60.3 0.0 4.5 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KSA00069.1 - 3.7e-29 100.7 0.5 1.1e-09 38.6 0.0 4.9 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KSA00069.1 - 4.6e-25 84.9 0.1 1.6e-06 28.0 0.0 5.7 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 KSA00069.1 - 8.2e-25 86.6 0.4 2.1e-06 27.9 0.0 5.6 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 KSA00069.1 - 4.7e-21 74.2 0.1 7.6e-06 26.1 0.0 6.3 6 0 0 6 6 6 4 Ankyrin repeat DHC PF09626.10 KSA00069.1 - 0.18 12.6 3.3 1.9 9.4 0.3 3.6 3 0 0 3 3 3 0 Dihaem cytochrome c CUE PF02845.16 KSA00070.1 - 1.1e-08 34.6 0.3 1.9e-08 33.8 0.3 1.4 1 0 0 1 1 1 1 CUE domain DUF2880 PF11082.8 KSA00070.1 - 0.76 10.1 5.2 7.8 6.9 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2880) TTL PF03133.15 KSA00071.1 - 2e-56 191.3 1.5 3.4e-56 190.5 1.5 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family SurE PF01975.17 KSA00071.1 - 5e-48 163.5 0.0 9.6e-48 162.5 0.0 1.5 1 0 0 1 1 1 1 Survival protein SurE ATPgrasp_YheCD PF14398.6 KSA00071.1 - 0.0021 17.4 0.5 0.19 10.9 0.0 2.5 3 0 0 3 3 3 2 YheC/D like ATP-grasp ATP-grasp_3 PF02655.14 KSA00071.1 - 0.037 14.1 0.0 3.8 7.5 0.0 2.6 2 0 0 2 2 2 0 ATP-grasp domain zf-Tim10_DDP PF02953.15 KSA00072.1 - 1.1e-16 60.2 0.2 1.4e-16 59.9 0.2 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger F_bP_aldolase PF01116.20 KSA00073.1 - 4.8e-91 305.1 0.0 5.4e-91 305.0 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Peptidase_C26 PF07722.13 KSA00073.1 - 0.098 12.4 0.0 0.82 9.4 0.0 2.0 2 0 0 2 2 2 0 Peptidase C26 Acetyltransf_1 PF00583.25 KSA00074.1 - 1.3e-15 57.7 0.0 1.7e-15 57.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KSA00074.1 - 2.2e-09 37.6 0.0 3.4e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KSA00074.1 - 6.3e-08 32.6 0.0 9.2e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KSA00074.1 - 1.9e-06 28.6 0.0 2.3e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KSA00074.1 - 7e-06 25.8 0.0 9.9e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KSA00074.1 - 5.1e-05 23.2 0.0 8.1e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein DUF3626 PF12294.8 KSA00074.1 - 0.041 12.9 0.0 0.054 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3626) Acetyltransf_CG PF14542.6 KSA00074.1 - 0.049 13.8 0.0 0.099 12.8 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 KSA00074.1 - 0.1 12.7 0.1 0.21 11.7 0.1 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PCNA_N PF00705.18 KSA00075.1 - 3.6e-49 165.7 5.9 1.1e-48 164.1 2.7 2.6 2 1 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 KSA00075.1 - 2.6e-47 160.2 0.0 4.9e-47 159.3 0.0 1.4 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain Rad1 PF02144.16 KSA00075.1 - 2e-06 27.1 0.7 0.00067 18.8 0.2 2.1 1 1 1 2 2 2 2 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.13 KSA00075.1 - 2.8e-06 27.0 0.4 3.5e-06 26.7 0.4 1.1 1 0 0 1 1 1 1 Rad9 Hus1 PF04005.12 KSA00075.1 - 4.8e-05 22.6 0.0 0.017 14.2 0.0 2.1 2 0 0 2 2 2 2 Hus1-like protein RXT2_N PF08595.11 KSA00076.1 - 1.2e-35 122.8 3.4 1.2e-35 122.8 3.4 2.9 2 1 0 2 2 2 1 RXT2-like, N-terminal Zip PF02535.22 KSA00076.1 - 0.0081 15.4 1.3 0.0081 15.4 1.3 1.7 2 0 0 2 2 2 1 ZIP Zinc transporter CENP-B_dimeris PF09026.10 KSA00076.1 - 0.031 14.7 0.8 0.031 14.7 0.8 3.1 2 1 1 3 3 3 0 Centromere protein B dimerisation domain ATG11 PF10377.9 KSA00077.1 - 3.3e-42 143.6 0.2 3.3e-42 143.6 0.2 4.8 4 1 0 5 5 5 1 Autophagy-related protein 11 TPR_MLP1_2 PF07926.12 KSA00077.1 - 0.25 11.4 31.6 0.69 10.0 7.8 3.6 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Pribosyltran_N PF13793.6 KSA00078.1 - 1.2e-42 144.6 0.4 1.6e-40 137.7 0.0 2.4 2 0 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 KSA00078.1 - 2.6e-40 138.4 2.4 3.5e-36 125.0 0.9 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 KSA00078.1 - 2.6e-15 56.3 0.6 1e-14 54.3 0.4 2.0 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KSA00078.1 - 0.003 17.0 0.1 0.0057 16.1 0.1 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase C9orf72-like PF15019.6 KSA00078.1 - 0.03 13.9 0.2 0.099 12.2 0.0 1.7 2 0 0 2 2 2 0 C9orf72-like protein family RFX_DNA_binding PF02257.15 KSA00079.1 - 1.5e-13 51.2 0.0 4.4e-13 49.7 0.0 1.8 1 0 0 1 1 1 1 RFX DNA-binding domain Carn_acyltransf PF00755.20 KSA00080.1 - 2.5e-192 640.6 0.2 2.8e-192 640.5 0.2 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Glyco_transf_21 PF13506.6 KSA00081.1 - 1.3e-13 50.8 0.0 2.8e-07 30.2 0.0 3.4 4 0 0 4 4 4 3 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 KSA00081.1 - 8.5e-08 32.4 0.0 2.5e-07 30.8 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KSA00081.1 - 1.3e-05 25.1 0.1 7.7e-05 22.6 0.1 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 2 APOBEC4 PF18775.1 KSA00081.1 - 0.065 13.4 0.0 0.21 11.8 0.0 1.9 2 0 0 2 2 2 0 APOBEC4 zf-HIT PF04438.16 KSA00082.1 - 0.021 14.7 14.0 0.034 14.0 14.0 1.4 1 0 0 1 1 1 0 HIT zinc finger Sec16 PF12932.7 KSA00082.1 - 0.12 12.9 0.8 0.38 11.4 0.7 1.8 1 1 1 2 2 2 0 Vesicle coat trafficking protein Sec16 mid-region UPF0203 PF05254.12 KSA00083.1 - 3.6e-27 94.4 4.0 4.4e-27 94.1 4.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) Cmc1 PF08583.10 KSA00083.1 - 0.00062 19.7 1.4 0.092 12.8 0.3 2.2 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like UCR_hinge PF02320.16 KSA00083.1 - 0.00065 19.9 0.5 0.00099 19.3 0.5 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein COX17 PF05051.13 KSA00083.1 - 0.0092 16.3 0.6 0.025 14.9 0.6 1.7 1 1 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) DUF5332 PF17266.2 KSA00083.1 - 0.028 14.1 0.2 0.031 13.9 0.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5332) Pet191_N PF10203.9 KSA00083.1 - 0.058 13.7 1.7 1.4 9.3 0.1 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 DUF3128 PF11326.8 KSA00083.1 - 0.065 13.6 4.2 1.7 9.1 4.2 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) COX6B PF02297.17 KSA00083.1 - 0.22 11.8 5.8 1.7 8.9 0.1 2.0 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb DASH_Ask1 PF08655.10 KSA00084.1 - 4.4e-28 97.0 0.9 8.3e-28 96.1 0.9 1.5 1 0 0 1 1 1 1 DASH complex subunit Ask1 SURF2 PF05477.11 KSA00084.1 - 0.024 14.3 0.9 0.024 14.3 0.9 2.8 3 0 0 3 3 3 0 Surfeit locus protein 2 (SURF2) CENP-B_dimeris PF09026.10 KSA00084.1 - 0.31 11.5 6.3 0.18 12.2 3.2 2.2 2 0 0 2 2 2 0 Centromere protein B dimerisation domain CBM9_1 PF06452.11 KSA00084.1 - 3 7.7 10.9 0.2 11.6 5.7 1.7 2 0 0 2 2 2 0 Carbohydrate family 9 binding domain-like RhoGAP PF00620.27 KSA00086.1 - 2.9e-42 144.1 0.0 5.6e-42 143.1 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 KSA00087.1 - 8.4e-14 51.5 25.4 8.1e-09 35.6 8.0 2.4 2 0 0 2 2 2 2 LIM domain P4Ha_N PF08336.11 KSA00087.1 - 0.0014 18.7 1.4 0.0031 17.5 1.4 1.5 1 0 0 1 1 1 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DivIC PF04977.15 KSA00087.1 - 7.6 6.4 8.3 7.1 6.5 2.0 2.6 2 0 0 2 2 2 0 Septum formation initiator Lipase_3 PF01764.25 KSA00088.1 - 1.4e-32 112.5 0.0 2.1e-32 111.9 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KSA00088.1 - 0.0064 17.1 0.0 0.0089 16.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KSA00088.1 - 0.023 14.0 0.0 0.034 13.4 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PGAP1 PF07819.13 KSA00088.1 - 0.085 12.6 0.2 0.14 11.8 0.2 1.3 1 0 0 1 1 1 0 PGAP1-like protein DUF2974 PF11187.8 KSA00088.1 - 0.088 12.4 0.1 2.1 7.8 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2974) Pyr_redox_2 PF07992.14 KSA00089.1 - 2.1e-11 43.6 0.0 1.3e-09 37.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KSA00089.1 - 0.00034 20.6 0.0 0.0031 17.5 0.0 2.5 3 0 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KSA00089.1 - 0.0083 16.3 0.0 0.12 12.6 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KSA00089.1 - 0.074 12.2 0.0 0.58 9.2 0.0 2.0 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 KSA00089.1 - 0.15 12.6 0.1 5.8 7.6 0.1 3.3 3 1 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KSA00089.1 - 0.17 11.1 0.2 37 3.4 0.1 3.4 3 1 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Glyco_hydro_114 PF03537.13 KSA00090.1 - 5e-88 294.3 0.8 6e-88 294.1 0.8 1.1 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 TraD_N PF12615.8 KSA00090.1 - 0.15 12.8 0.1 15 6.5 0.0 2.4 1 1 1 2 2 2 0 F sex factor protein N terminal Ferric_reduct PF01794.19 KSA00091.1 - 1.5e-20 73.6 6.7 1.5e-20 73.6 6.7 2.3 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KSA00091.1 - 9.5e-14 51.8 0.1 1.5e-13 51.2 0.1 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KSA00091.1 - 2.8e-13 49.9 0.0 6.8e-13 48.7 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain Sugar_tr PF00083.24 KSA00092.1 - 7.2e-133 443.8 20.0 8.3e-133 443.5 20.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KSA00092.1 - 4.5e-24 85.0 52.9 3.5e-23 82.1 25.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Epimerase PF01370.21 KSA00093.1 - 3.4e-19 69.3 0.0 5.8e-19 68.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KSA00093.1 - 6.5e-14 51.6 0.0 8.9e-14 51.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KSA00093.1 - 5.4e-07 29.3 0.0 9e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KSA00093.1 - 1.4e-06 28.3 0.0 2.9e-06 27.3 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 KSA00093.1 - 1.2e-05 24.9 0.0 2.4e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.12 KSA00093.1 - 0.0001 21.6 0.0 0.06 12.5 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein adh_short_C2 PF13561.6 KSA00093.1 - 0.0021 17.6 0.0 0.0041 16.7 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.15 KSA00093.1 - 0.004 16.3 0.1 0.007 15.5 0.1 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 KSA00093.1 - 0.0047 16.5 0.1 0.049 13.2 0.0 2.1 2 0 0 2 2 2 1 NmrA-like family KR PF08659.10 KSA00093.1 - 0.015 15.2 0.0 0.031 14.2 0.0 1.5 1 0 0 1 1 1 0 KR domain Ofd1_CTDD PF10637.9 KSA00093.1 - 0.067 12.5 0.1 0.11 11.8 0.1 1.3 1 0 0 1 1 1 0 Oxoglutarate and iron-dependent oxygenase degradation C-term FMN_bind_2 PF04299.12 KSA00094.1 - 3.1e-60 202.7 0.1 4e-60 202.4 0.1 1.1 1 0 0 1 1 1 1 Putative FMN-binding domain THF_DHG_CYH PF00763.23 KSA00094.1 - 0.0058 16.9 0.1 0.027 14.7 0.1 1.9 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain RRM_1 PF00076.22 KSA00095.1 - 1.5e-16 60.0 0.0 2.5e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fasciclin PF02469.22 KSA00096.1 - 2.1e-16 60.3 0.5 1.3e-07 31.9 0.0 4.2 4 1 0 4 4 4 2 Fasciclin domain Aa_trans PF01490.18 KSA00097.1 - 2.8e-66 223.9 31.8 3.4e-66 223.6 31.8 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein EamA PF00892.20 KSA00098.1 - 4.1e-13 49.7 29.7 1.3e-06 28.7 14.3 2.2 2 0 0 2 2 2 2 EamA-like transporter family SLC35F PF06027.12 KSA00098.1 - 4.6e-06 26.4 15.9 6e-06 26.0 15.9 1.1 1 0 0 1 1 1 1 Solute carrier family 35 PUNUT PF16913.5 KSA00098.1 - 7.6e-05 22.1 10.0 7.6e-05 22.1 10.0 1.5 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport TPT PF03151.16 KSA00098.1 - 0.001 18.5 13.3 0.0024 17.3 13.3 1.5 1 1 0 1 1 1 1 Triose-phosphate Transporter family DUF2198 PF09964.9 KSA00098.1 - 0.03 14.4 9.8 0.12 12.5 0.7 3.8 2 2 2 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2198) DUF2613 PF11021.8 KSA00098.1 - 0.06 13.5 0.1 0.28 11.3 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) DUF4064 PF13273.6 KSA00098.1 - 1.2 9.4 11.7 5.2 7.4 0.9 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) OST3_OST6 PF04756.13 KSA00099.1 - 7.6e-74 248.7 1.9 9.4e-74 248.4 1.9 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family UDG PF03167.19 KSA00100.1 - 7.6e-18 65.0 0.3 2.8e-17 63.1 0.0 1.9 1 1 1 2 2 2 1 Uracil DNA glycosylase superfamily PH_12 PF16457.5 KSA00100.1 - 0.046 14.2 2.4 0.11 13.0 2.4 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain SNF2_N PF00176.23 KSA00101.1 - 1.5e-74 250.8 0.3 7e-74 248.6 0.1 2.2 2 0 0 2 2 2 1 SNF2 family N-terminal domain SLIDE PF09111.10 KSA00101.1 - 9.8e-38 128.7 1.7 9.8e-38 128.7 1.7 3.1 2 0 0 2 2 2 1 SLIDE HAND PF09110.11 KSA00101.1 - 5.1e-32 110.9 3.7 5.1e-32 110.9 3.7 3.2 3 0 0 3 3 3 1 HAND Helicase_C PF00271.31 KSA00101.1 - 7.3e-20 71.4 0.0 1.3e-18 67.3 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KSA00101.1 - 8.1e-12 45.5 0.0 8.1e-12 45.5 0.0 3.9 5 0 0 5 5 5 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KSA00101.1 - 3.2e-05 23.8 0.0 0.00019 21.3 0.0 2.3 3 0 0 3 3 3 1 DEAD/DEAH box helicase Myb_DNA-binding PF00249.31 KSA00101.1 - 0.00012 22.2 0.0 0.038 14.2 0.0 3.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain DOT1 PF08123.13 KSA00102.1 - 4.6e-76 254.9 0.1 8.4e-76 254.1 0.1 1.5 1 0 0 1 1 1 1 Histone methylation protein DOT1 PALP PF00291.25 KSA00104.1 - 1.1e-54 185.8 0.0 1.3e-54 185.6 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Rad33 PF08730.10 KSA00105.1 - 1.6e-68 229.9 5.6 2e-68 229.6 5.6 1.1 1 0 0 1 1 1 1 Rad33 NUMOD1 PF07453.13 KSA00105.1 - 0.036 14.3 0.3 0.13 12.5 0.3 1.9 1 0 0 1 1 1 0 NUMOD1 domain Pro_isomerase PF00160.21 KSA00106.1 - 6.1e-26 91.6 0.0 7.6e-26 91.3 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD EMP24_GP25L PF01105.24 KSA00108.1 - 8.8e-40 136.6 0.0 1.2e-39 136.1 0.0 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD EzrA PF06160.12 KSA00108.1 - 0.084 11.0 1.3 0.12 10.5 1.3 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Ribosomal_L33 PF00471.20 KSA00109.1 - 0.00022 21.6 0.2 0.00035 21.0 0.1 1.4 1 1 0 1 1 1 1 Ribosomal protein L33 Striatin PF08232.12 KSA00110.1 - 5.4e-16 59.6 2.9 5.4e-16 59.6 2.9 4.0 3 2 1 4 4 4 1 Striatin family Polysacc_synt_4 PF04669.13 KSA00111.1 - 9.1e-19 67.7 0.2 4.8e-17 62.1 0.2 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis Amino_oxidase PF01593.24 KSA00112.1 - 1.9e-62 212.1 0.0 2.4e-62 211.7 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KSA00112.1 - 4.8e-11 42.7 0.0 9.6e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KSA00112.1 - 0.012 15.2 0.0 0.032 13.8 0.0 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KSA00112.1 - 0.022 14.8 0.0 0.065 13.2 0.0 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 KSA00112.1 - 0.027 15.0 0.0 0.093 13.3 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KSA00112.1 - 0.065 12.5 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KSA00112.1 - 0.15 11.2 0.0 0.29 10.3 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain AlaDh_PNT_C PF01262.21 KSA00112.1 - 0.16 11.3 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain UQ_con PF00179.26 KSA00113.1 - 3.7e-50 169.2 0.0 4.2e-50 169.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme SNase PF00565.17 KSA00114.1 - 1.9e-40 137.7 0.3 6.8e-10 39.4 0.0 5.4 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.24 KSA00114.1 - 3.2e-16 59.4 0.0 8e-16 58.2 0.0 1.7 1 0 0 1 1 1 1 Tudor domain LBR_tudor PF09465.10 KSA00114.1 - 0.0042 16.8 1.0 0.01 15.7 0.1 2.0 2 0 0 2 2 2 1 Lamin-B receptor of TUDOR domain Pho88 PF10032.9 KSA00115.1 - 6.6e-80 266.7 0.8 7.4e-80 266.5 0.8 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) SET PF00856.28 KSA00116.1 - 2.2e-06 28.2 0.2 5.2e-06 26.9 0.2 1.7 1 0 0 1 1 1 1 SET domain SCO1-SenC PF02630.14 KSA00117.1 - 7.8e-44 148.8 0.0 1.1e-43 148.4 0.0 1.2 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 KSA00117.1 - 0.0024 17.8 0.0 0.0044 16.9 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family NMT1 PF09084.11 KSA00118.1 - 2.6e-80 269.4 0.0 3.2e-80 269.1 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 KSA00118.1 - 9.2e-05 22.2 0.0 0.025 14.3 0.0 2.4 3 0 0 3 3 3 2 NMT1-like family PhyH PF05721.13 KSA00119.1 - 1.1e-45 156.5 0.1 1.3e-45 156.3 0.1 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Baculo_11_kDa PF06143.11 KSA00119.1 - 0.19 11.3 0.1 0.43 10.2 0.1 1.5 1 0 0 1 1 1 0 Baculovirus 11 kDa family FHA PF00498.26 KSA00120.1 - 8.8e-08 32.4 0.2 1.8e-07 31.4 0.2 1.6 1 0 0 1 1 1 1 FHA domain Macoilin PF09726.9 KSA00120.1 - 7.9 4.9 20.1 4 5.9 18.3 1.3 1 1 0 1 1 1 0 Macoilin family Spt20 PF12090.8 KSA00121.1 - 4.7e-60 203.1 3.5 4.7e-60 203.1 3.5 8.1 3 1 1 4 4 4 1 Spt20 family DCP1 PF06058.13 KSA00122.1 - 1e-27 96.3 0.1 1.6e-27 95.8 0.1 1.3 1 0 0 1 1 1 1 Dcp1-like decapping family Redoxin PF08534.10 KSA00123.1 - 2.6e-35 121.3 0.0 3e-35 121.1 0.0 1.0 1 0 0 1 1 1 1 Redoxin RF-1 PF00472.20 KSA00124.1 - 8.6e-22 77.3 0.3 1.4e-21 76.6 0.3 1.2 1 0 0 1 1 1 1 RF-1 domain MgsA_C PF12002.8 KSA00124.1 - 0.054 13.4 0.1 0.11 12.4 0.0 1.5 2 0 0 2 2 2 0 MgsA AAA+ ATPase C terminal efThoc1 PF11957.8 KSA00125.1 - 4.3e-37 127.9 30.3 4.3e-37 127.9 30.3 1.6 2 0 0 2 2 2 1 THO complex subunit 1 transcription elongation factor Rif1_N PF12231.8 KSA00126.1 - 4.4e-31 108.2 16.1 1.2e-30 106.8 16.1 1.8 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal Pkinase PF00069.25 KSA00127.1 - 2.3e-24 86.2 0.0 8.5e-23 81.0 0.0 2.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KSA00127.1 - 9.3e-13 48.1 0.6 1.2e-10 41.2 0.3 3.0 2 1 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KSA00127.1 - 0.0057 15.5 0.0 0.0094 14.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KSA00127.1 - 0.0083 16.1 0.2 0.036 14.0 0.2 2.0 2 1 0 2 2 2 1 Phosphotransferase enzyme family UPF0547 PF10571.9 KSA00127.1 - 0.14 12.3 0.5 0.24 11.5 0.5 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 Kdo PF06293.14 KSA00127.1 - 0.73 9.1 3.7 0.62 9.4 0.2 2.1 1 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family PAP_assoc PF03828.19 KSA00128.1 - 9.6e-17 61.0 0.1 4.2e-16 58.9 0.1 2.2 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KSA00128.1 - 1.3e-15 57.4 1.4 2.1e-14 53.6 0.0 3.2 1 1 1 2 2 2 1 Nucleotidyltransferase domain Polbeta PF18765.1 KSA00128.1 - 0.0001 22.3 0.0 0.0003 20.8 0.0 1.9 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase Ras PF00071.22 KSA00129.1 - 7.5e-46 155.7 0.6 9.4e-46 155.4 0.6 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KSA00129.1 - 1.4e-36 125.3 0.9 2.1e-36 124.7 0.9 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KSA00129.1 - 8.5e-16 57.9 0.0 1.3e-15 57.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KSA00129.1 - 3.2e-07 30.4 0.4 5.5e-07 29.7 0.1 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.10 KSA00129.1 - 8.9e-07 28.5 0.1 1.1e-06 28.2 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KSA00129.1 - 5e-06 26.0 0.2 8.1e-06 25.4 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KSA00129.1 - 4.9e-05 23.3 0.0 0.3 11.0 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KSA00129.1 - 0.00075 19.1 0.7 0.42 10.1 0.0 2.9 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 KSA00129.1 - 0.0067 16.0 0.1 0.042 13.4 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_24 PF13479.6 KSA00129.1 - 0.009 15.7 0.9 0.046 13.4 0.9 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KSA00129.1 - 0.01 16.2 0.0 0.012 15.9 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain PRK PF00485.18 KSA00129.1 - 0.012 15.4 0.1 0.018 14.8 0.1 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family TniB PF05621.11 KSA00129.1 - 0.015 14.7 0.0 0.032 13.6 0.0 1.6 1 0 0 1 1 1 0 Bacterial TniB protein AAA_28 PF13521.6 KSA00129.1 - 0.026 14.8 0.0 0.039 14.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KSA00129.1 - 0.04 13.8 0.0 0.053 13.4 0.0 1.3 1 0 0 1 1 1 0 NTPase AAA_22 PF13401.6 KSA00129.1 - 0.041 14.2 0.2 0.42 10.9 0.2 2.3 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 KSA00129.1 - 0.049 13.4 0.1 0.94 9.2 0.1 2.5 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DUF2802 PF10975.8 KSA00130.1 - 0.075 13.2 0.1 0.25 11.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2802) Laminin_II PF06009.12 KSA00130.1 - 0.29 11.1 5.0 0.11 12.5 1.9 1.8 2 0 0 2 2 2 0 Laminin Domain II STN1_2 PF09170.10 KSA00130.1 - 0.94 9.7 4.3 0.23 11.7 0.7 1.8 2 1 0 2 2 2 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 Anp1 PF03452.14 KSA00131.1 - 1.8e-106 355.4 0.0 2.8e-106 354.8 0.0 1.3 2 0 0 2 2 2 1 Anp1 Glycos_transf_2 PF00535.26 KSA00131.1 - 0.029 14.2 0.0 0.061 13.1 0.0 1.7 1 1 0 1 1 1 0 Glycosyl transferase family 2 EF1G PF00647.19 KSA00132.1 - 4.8e-15 55.5 0.5 4.8e-15 55.5 0.5 1.5 2 0 0 2 2 2 1 Elongation factor 1 gamma, conserved domain GST_N PF02798.20 KSA00133.1 - 5.3e-05 23.5 0.1 0.00012 22.4 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain WASH-7_C PF14746.6 KSA00133.1 - 0.15 11.7 1.2 0.24 11.1 1.2 1.2 1 0 0 1 1 1 0 WASH complex subunit 7, C-terminal Zn_clus PF00172.18 KSA00134.1 - 7.4e-06 26.0 12.0 1.4e-05 25.1 12.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 KSA00135.1 - 4.6e-62 210.4 41.5 5.6e-62 210.1 41.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KSA00135.1 - 6e-19 68.2 25.0 6e-19 68.2 25.0 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily RRM_1 PF00076.22 KSA00136.1 - 0.00031 20.5 0.5 1.1 9.1 0.0 3.9 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 KSA00136.1 - 0.024 14.5 2.7 0.28 11.0 0.1 2.6 2 0 0 2 2 2 0 Rrp7 RRM-like N-terminal domain Flavoprotein PF02441.19 KSA00137.1 - 1.3e-48 164.7 0.1 2.4e-48 163.9 0.1 1.4 1 0 0 1 1 1 1 Flavoprotein SGT1 PF07093.11 KSA00137.1 - 0.35 9.2 11.1 0.6 8.5 11.1 1.3 1 0 0 1 1 1 0 SGT1 protein SAPS PF04499.15 KSA00137.1 - 1.5 7.6 7.8 2.9 6.6 7.8 1.5 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nop14 PF04147.12 KSA00137.1 - 2.9 6.0 34.5 4.3 5.4 34.5 1.2 1 0 0 1 1 1 0 Nop14-like family Nop53 PF07767.11 KSA00137.1 - 3 7.2 15.9 5.8 6.2 15.9 1.5 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) CobT PF06213.12 KSA00137.1 - 6.9 6.0 25.3 15 4.9 25.3 1.5 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SDA1 PF05285.12 KSA00137.1 - 7.6 5.8 36.2 15 4.9 36.2 1.4 1 0 0 1 1 1 0 SDA1 LRR_8 PF13855.6 KSA00138.1 - 6.1e-11 41.9 2.7 3.1e-06 26.8 0.1 4.1 1 1 4 5 5 5 3 Leucine rich repeat LRR_9 PF14580.6 KSA00138.1 - 0.00025 20.6 9.6 0.0032 17.0 1.6 2.4 1 1 1 2 2 2 2 Leucine-rich repeat LRR_4 PF12799.7 KSA00138.1 - 0.0017 18.7 29.8 0.0083 16.5 0.4 5.1 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KSA00138.1 - 0.006 16.4 0.3 0.017 15.0 0.3 1.8 1 0 0 1 1 1 1 F-box-like FNIP PF05725.12 KSA00138.1 - 0.013 15.7 1.3 0.013 15.7 1.3 4.4 5 0 0 5 5 5 0 FNIP Repeat LRR_5 PF13306.6 KSA00138.1 - 0.018 15.0 6.9 0.019 14.9 0.4 3.0 2 1 0 3 3 3 0 BspA type Leucine rich repeat region (6 copies) F-box PF00646.33 KSA00138.1 - 0.059 13.3 0.7 0.16 11.9 0.7 1.7 1 0 0 1 1 1 0 F-box domain LRR_6 PF13516.6 KSA00138.1 - 0.074 13.1 4.0 1 9.6 0.0 4.3 4 0 0 4 4 4 0 Leucine Rich repeat MAP65_ASE1 PF03999.12 KSA00139.1 - 9.9e-56 189.7 40.0 9.9e-56 189.7 40.0 2.7 2 1 0 2 2 2 1 Microtubule associated protein (MAP65/ASE1 family) Nup54 PF13874.6 KSA00139.1 - 6 7.0 10.4 2.2 8.4 0.8 3.6 3 0 0 3 3 3 0 Nucleoporin complex subunit 54 PQ-loop PF04193.14 KSA00141.1 - 2.2e-35 120.2 17.7 2.2e-19 69.0 4.1 2.7 3 0 0 3 3 3 2 PQ loop repeat LURAP PF14854.6 KSA00141.1 - 0.064 13.2 0.3 0.13 12.3 0.3 1.5 1 0 0 1 1 1 0 Leucine rich adaptor protein MtN3_slv PF03083.16 KSA00141.1 - 0.22 11.6 0.2 0.22 11.6 0.2 2.5 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange ER_lumen_recept PF00810.18 KSA00141.1 - 7.3 7.4 10.9 0.68 10.8 0.2 3.2 2 2 1 3 3 3 0 ER lumen protein retaining receptor Pyridoxal_deC PF00282.19 KSA00142.1 - 1.3e-17 63.6 0.0 2.1e-17 62.9 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DegT_DnrJ_EryC1 PF01041.17 KSA00142.1 - 8e-06 25.4 0.0 1.3e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 KSA00142.1 - 2e-05 23.7 0.0 5.8e-05 22.2 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KSA00142.1 - 0.0083 15.3 0.0 0.013 14.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KSA00142.1 - 0.066 11.7 0.0 0.15 10.6 0.0 1.5 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme PLU-1 PF08429.11 KSA00142.1 - 0.079 12.1 0.1 2.1 7.4 0.2 2.2 2 0 0 2 2 2 0 PLU-1-like protein HDA2-3 PF11496.8 KSA00143.1 - 9.3e-66 222.0 11.2 9.3e-66 222.0 11.2 2.1 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 Mit_KHE1 PF10173.9 KSA00143.1 - 0.075 13.1 2.9 0.16 12.0 2.9 1.5 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related Nup54 PF13874.6 KSA00143.1 - 0.23 11.6 9.0 0.1 12.7 1.4 2.9 1 1 0 2 2 2 0 Nucleoporin complex subunit 54 SlyX PF04102.12 KSA00143.1 - 0.28 11.8 6.9 0.26 11.9 0.6 3.2 2 0 0 2 2 2 0 SlyX BLOC1_2 PF10046.9 KSA00143.1 - 0.64 10.4 32.0 0.052 13.9 4.9 5.0 4 1 1 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF948 PF06103.11 KSA00143.1 - 3.4 8.0 8.5 0.56 10.5 0.9 3.2 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) EF-hand_4 PF12763.7 KSA00144.1 - 8.3e-07 28.9 0.0 2.1e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand CHASE6_C PF17150.4 KSA00144.1 - 0.012 16.3 0.0 0.036 14.7 0.0 1.9 1 0 0 1 1 1 0 C-terminal domain of two-partite extracellular sensor domain EF-hand_1 PF00036.32 KSA00144.1 - 0.027 14.0 0.0 0.068 12.8 0.0 1.8 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.6 KSA00144.1 - 0.042 14.3 0.0 0.13 12.7 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_8 PF13833.6 KSA00144.1 - 0.13 12.1 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair PIN_6 PF17146.4 KSA00145.1 - 6.6e-32 109.9 0.2 2.2e-31 108.2 0.0 2.1 2 0 0 2 2 2 1 PIN domain of ribonuclease NOB1_Zn_bind PF08772.11 KSA00145.1 - 1.2e-24 86.2 1.1 2.6e-24 85.1 1.1 1.6 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like C2-set PF05790.15 KSA00145.1 - 0.01 16.0 1.1 0.15 12.3 1.7 2.3 2 0 0 2 2 2 0 Immunoglobulin C2-set domain Zn-ribbon_8 PF09723.10 KSA00145.1 - 0.46 10.6 6.6 0.14 12.3 3.1 2.0 2 0 0 2 2 2 0 Zinc ribbon domain Zn_Tnp_IS91 PF14319.6 KSA00145.1 - 1.8 8.6 5.3 0.32 11.0 0.4 2.2 2 0 0 2 2 2 0 Transposase zinc-binding domain GST_C PF00043.25 KSA00146.1 - 1.8e-10 40.9 0.1 5.5e-10 39.3 0.0 1.8 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KSA00146.1 - 1.1e-09 38.3 0.0 1.7e-09 37.7 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KSA00146.1 - 2.6e-06 27.3 0.0 8e-06 25.8 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KSA00147.1 - 3.2e-08 33.6 0.0 5.6e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KSA00147.1 - 1.1e-06 28.8 0.0 1.8e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KSA00147.1 - 1e-05 25.4 0.0 1.8e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 KSA00147.1 - 0.074 12.9 0.0 0.35 10.7 0.0 2.0 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Glyco_transf_15 PF01793.16 KSA00148.1 - 1.2e-117 392.8 17.2 1.5e-117 392.5 17.2 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Nab6_mRNP_bdg PF10567.9 KSA00148.1 - 0.036 13.6 0.5 0.05 13.1 0.1 1.5 2 0 0 2 2 2 0 RNA-recognition motif tRNA-synt_2 PF00152.20 KSA00150.1 - 1.4e-104 349.6 0.1 1.8e-104 349.2 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KSA00150.1 - 1e-05 25.4 0.0 2.1e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KSA00150.1 - 0.0099 15.4 0.0 0.044 13.3 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.25 KSA00150.1 - 0.14 12.1 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) NAAA-beta PF15508.6 KSA00150.1 - 0.17 12.2 0.3 1 9.7 0.0 2.5 2 0 0 2 2 2 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase PUF PF00806.19 KSA00151.1 - 2.7e-25 86.6 3.6 0.0024 17.5 0.1 7.8 7 0 0 7 7 7 7 Pumilio-family RNA binding repeat Tim29 PF10171.9 KSA00151.1 - 0.05 13.1 0.0 0.15 11.6 0.0 1.8 1 0 0 1 1 1 0 Translocase of the Inner Mitochondrial membrane 29 Homeodomain PF00046.29 KSA00152.1 - 2e-17 62.8 1.1 3.6e-17 61.9 1.1 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KSA00152.1 - 0.00037 20.3 0.9 0.00085 19.2 0.9 1.6 1 0 0 1 1 1 1 Homeobox KN domain ATG16 PF08614.11 KSA00154.1 - 5e-15 56.3 29.2 1.1e-13 51.9 25.5 2.0 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) DUF2205 PF10224.9 KSA00154.1 - 0.012 15.6 1.6 0.012 15.6 1.6 3.4 1 1 1 3 3 3 0 Short coiled-coil protein Med21 PF11221.8 KSA00154.1 - 0.025 14.8 13.3 0.048 13.9 13.3 1.6 1 1 0 1 1 1 0 Subunit 21 of Mediator complex bZIP_1 PF00170.21 KSA00154.1 - 0.74 10.0 25.9 0.92 9.6 1.5 3.5 2 1 1 3 3 3 0 bZIP transcription factor YabA PF06156.13 KSA00154.1 - 2.4 8.9 24.1 0.79 10.4 8.0 3.2 1 1 1 2 2 2 0 Initiation control protein YabA Atg14 PF10186.9 KSA00154.1 - 3.4 6.7 20.2 6.3 5.8 20.3 1.5 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 PRKG1_interact PF15898.5 KSA00154.1 - 6.6 7.7 26.2 5 8.1 4.4 2.3 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain zf-CRD PF17979.1 KSA00154.1 - 9.1 6.4 10.1 0.82 9.8 1.6 2.3 1 1 1 2 2 2 0 Cysteine rich domain with multizinc binding regions ADH_N PF08240.12 KSA00155.1 - 1.2e-29 102.4 0.8 2.2e-29 101.5 0.2 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KSA00155.1 - 1.1e-26 93.4 0.5 1.8e-26 92.6 0.5 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KSA00155.1 - 7.1e-06 27.1 0.0 1.7e-05 25.9 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 KSA00155.1 - 0.012 15.1 0.2 0.022 14.2 0.2 1.5 1 0 0 1 1 1 0 short chain dehydrogenase ACP_syn_III_C PF08541.10 KSA00155.1 - 0.14 12.3 0.3 0.55 10.4 0.1 2.1 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Glyco_transf_22 PF03901.17 KSA00156.1 - 3.7e-93 313.0 29.8 4.4e-93 312.8 29.8 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF2645 PF10840.8 KSA00156.1 - 0.044 14.4 0.7 0.044 14.4 0.7 3.7 2 1 2 4 4 4 0 Protein of unknown function (DUF2645) Peptidase_C2 PF00648.21 KSA00157.1 - 3.5e-14 52.5 0.0 6.7e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 KSA00157.1 - 1.2e-08 35.3 2.5 5e-08 33.3 0.0 2.6 3 0 0 3 3 3 1 Calpain large subunit, domain III OST3_OST6 PF04756.13 KSA00158.1 - 3.2e-100 335.3 6.6 3.6e-100 335.1 6.6 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Yip1 PF04893.17 KSA00158.1 - 0.0014 18.3 0.9 0.0014 18.3 0.9 2.2 1 1 1 2 2 2 1 Yip1 domain DUF3278 PF11683.8 KSA00158.1 - 0.0045 17.1 7.7 0.018 15.1 0.6 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3278) Ku PF02735.16 KSA00158.1 - 0.14 11.8 0.1 5 6.8 0.1 2.2 2 0 0 2 2 2 0 Ku70/Ku80 beta-barrel domain 7TM-7TMR_HD PF07698.11 KSA00158.1 - 1.1 8.9 16.0 0.29 10.9 6.1 2.2 2 0 0 2 2 2 0 7TM receptor with intracellular HD hydrolase DUF2516 PF10724.9 KSA00158.1 - 1.1 9.5 5.1 0.21 11.9 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2516) FeoB_C PF07664.12 KSA00158.1 - 5.6 6.7 9.4 12 5.7 0.3 2.7 2 0 0 2 2 2 0 Ferrous iron transport protein B C terminus Snapin_Pallidin PF14712.6 KSA00159.1 - 0.00091 19.6 2.4 0.00091 19.6 2.4 1.9 2 0 0 2 2 2 1 Snapin/Pallidin Latarcin PF10279.9 KSA00159.1 - 0.017 15.5 0.6 0.028 14.8 0.4 1.8 1 1 0 1 1 1 0 Latarcin precursor DUF4559 PF15112.6 KSA00159.1 - 0.16 11.6 5.0 0.24 11.0 4.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4559) DUF676 PF05057.14 KSA00160.1 - 6.5e-52 176.2 0.1 1.1e-51 175.5 0.1 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) LCAT PF02450.15 KSA00160.1 - 0.00011 21.6 0.0 0.00021 20.6 0.0 1.4 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Lipase_3 PF01764.25 KSA00160.1 - 0.0026 17.6 0.0 0.007 16.2 0.0 1.7 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.13 KSA00160.1 - 0.0048 16.6 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein RNA_pol_Rpb4 PF03874.16 KSA00161.1 - 1.1e-31 109.6 5.5 1.9e-31 109.0 5.5 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb4 RSS_P20 PF11757.8 KSA00161.1 - 0.0023 18.3 1.0 0.0023 18.3 1.0 1.9 2 0 0 2 2 2 1 Suppressor of RNA silencing P21-like N-terminal domain RNA_pol_3_Rpc31 PF11705.8 KSA00161.1 - 0.014 15.6 7.0 0.022 15.0 7.0 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 BioT2 PF15368.6 KSA00161.1 - 0.02 14.9 0.8 0.02 14.9 0.8 1.9 1 1 1 2 2 2 0 Spermatogenesis family BioT2 ACR_tran PF00873.19 KSA00161.1 - 0.023 12.4 0.0 0.023 12.4 0.0 1.0 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family ING PF12998.7 KSA00161.1 - 0.029 15.0 7.2 0.13 12.9 0.3 2.9 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding DUF1657 PF07870.11 KSA00161.1 - 0.07 13.0 0.0 0.22 11.4 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1657) Ku_C PF03730.14 KSA00161.1 - 0.17 12.6 4.0 0.94 10.2 0.5 2.3 2 0 0 2 2 2 0 Ku70/Ku80 C-terminal arm ANAPC15 PF15243.6 KSA00161.1 - 1.7 9.1 13.7 0.087 13.2 6.6 2.2 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 15 GCD14 PF08704.10 KSA00162.1 - 4e-06 26.7 0.0 0.00062 19.5 0.0 2.3 2 0 0 2 2 2 2 tRNA methyltransferase complex GCD14 subunit GCD14_N PF14801.6 KSA00162.1 - 3.5e-05 23.5 0.0 9.3e-05 22.2 0.0 1.7 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit N-term ssDNA-exonuc_C PF10141.9 KSA00162.1 - 0.13 11.8 0.0 0.37 10.4 0.0 1.7 2 0 0 2 2 2 0 Single-strand DNA-specific exonuclease, C terminal domain Ten1 PF12658.7 KSA00163.1 - 1.6e-20 73.2 0.8 2e-20 72.9 0.8 1.1 1 0 0 1 1 1 1 Telomere capping, CST complex subunit PIH1_CS PF18201.1 KSA00163.1 - 0.12 12.8 0.1 0.2 12.1 0.1 1.3 1 0 0 1 1 1 0 PIH1 CS-like domain Fungal_trans PF04082.18 KSA00164.1 - 1.6e-35 122.4 11.8 1.4e-34 119.4 11.0 2.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KSA00164.1 - 3.9e-10 39.7 10.6 9.2e-10 38.5 10.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PFK PF00365.20 KSA00166.1 - 1.2e-184 612.1 0.9 1e-100 336.7 0.1 2.2 2 0 0 2 2 2 2 Phosphofructokinase Pfk_N PF18468.1 KSA00166.1 - 9.5e-36 122.2 0.0 1.9e-35 121.2 0.0 1.6 1 0 0 1 1 1 1 Phosphofructokinase N-terminal domain yeast DAGK_cat PF00781.24 KSA00166.1 - 0.16 11.6 0.2 0.58 9.8 0.1 2.0 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain UVR PF02151.19 KSA00166.1 - 0.18 11.6 0.1 0.42 10.4 0.1 1.6 1 0 0 1 1 1 0 UvrB/uvrC motif Glyco_hydro_16 PF00722.21 KSA00167.1 - 2.5e-42 144.4 0.1 3.8e-42 143.8 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SMC_Nse1 PF07574.13 KSA00168.1 - 4.7e-25 88.6 0.5 8e-23 81.3 0.5 2.1 1 1 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.11 KSA00168.1 - 1.5e-08 34.8 6.9 2.4e-08 34.2 6.9 1.3 1 0 0 1 1 1 1 RING-like domain zf-ANAPC11 PF12861.7 KSA00168.1 - 0.00022 21.2 1.3 0.00038 20.4 1.3 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-HC5HC2H PF13771.6 KSA00168.1 - 0.0017 18.5 2.0 0.0037 17.5 2.0 1.6 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-rbx1 PF12678.7 KSA00168.1 - 0.014 15.7 0.7 0.025 14.9 0.7 1.3 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-HC5HC2H_2 PF13832.6 KSA00168.1 - 0.023 14.8 1.6 0.041 14.0 1.6 1.4 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-RING_2 PF13639.6 KSA00168.1 - 0.15 12.4 4.2 0.32 11.3 4.2 1.6 1 1 0 1 1 1 0 Ring finger domain PHD PF00628.29 KSA00168.1 - 0.98 9.4 5.5 16 5.5 6.2 2.1 1 1 1 2 2 2 0 PHD-finger SPRY PF00622.28 KSA00169.1 - 0.0064 16.6 0.0 0.16 12.1 0.0 2.7 2 1 0 2 2 2 1 SPRY domain Fimbrial_CS1 PF04449.12 KSA00170.1 - 0.022 14.9 0.1 0.058 13.5 0.1 1.7 1 0 0 1 1 1 0 CS1 type fimbrial major subunit HSF_DNA-bind PF00447.17 KSA00171.1 - 2.4e-26 92.2 0.4 6.2e-26 90.8 0.4 1.8 1 0 0 1 1 1 1 HSF-type DNA-binding Halo_GVPC PF05465.13 KSA00171.1 - 0.31 11.3 2.3 13 6.2 0.2 3.0 1 1 2 3 3 3 0 Halobacterial gas vesicle protein C (GVPC) repeat NOP19 PF10863.8 KSA00172.1 - 2.3e-25 89.1 7.3 2.3e-25 89.1 7.3 1.9 2 0 0 2 2 2 1 Nucleolar protein 19 DUF3245 PF11595.8 KSA00172.1 - 0.21 12.1 13.1 0.94 9.9 13.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3245) SH2_2 PF14633.6 KSA00173.1 - 2e-76 256.2 0.5 2e-76 256.2 0.5 2.1 2 0 0 2 2 2 1 SH2 domain HTH_44 PF14641.6 KSA00173.1 - 5.2e-38 130.0 2.6 5.2e-38 130.0 2.6 3.0 3 0 0 3 3 3 1 Helix-turn-helix DNA-binding domain of SPT6 YqgF PF14639.6 KSA00173.1 - 3.7e-31 107.9 0.0 1.2e-30 106.2 0.0 2.0 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HHH_7 PF14635.6 KSA00173.1 - 3.1e-30 104.6 0.0 1.3e-29 102.6 0.0 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix motif SPT6_acidic PF14632.6 KSA00173.1 - 2.6e-21 76.0 24.7 2.6e-21 76.0 24.7 4.8 2 1 1 3 3 3 1 Acidic N-terminal SPT6 SH2 PF00017.24 KSA00173.1 - 1.4e-06 28.3 0.0 4e-06 26.8 0.0 1.9 1 0 0 1 1 1 1 SH2 domain HHH_9 PF17674.1 KSA00173.1 - 4.9e-06 27.4 0.3 3.9e-05 24.5 0.3 2.8 1 1 0 1 1 1 1 HHH domain TauD PF02668.16 KSA00174.1 - 5.5e-46 157.5 0.0 7.6e-46 157.1 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 KSA00174.1 - 3.5e-05 24.3 0.1 0.00055 20.5 0.0 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF971) ThrE PF06738.12 KSA00175.1 - 1.1e-71 241.0 13.3 5e-68 229.0 2.6 2.4 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 KSA00175.1 - 5.7e-10 39.4 25.3 3.6e-09 36.8 8.3 2.3 2 0 0 2 2 2 2 Threonine/Serine exporter, ThrE PDCD2_C PF04194.13 KSA00176.1 - 1.5e-37 129.3 9.4 6.6e-37 127.3 0.1 3.1 3 1 0 3 3 3 2 Programmed cell death protein 2, C-terminal putative domain EGF_CA PF07645.15 KSA00176.1 - 0.07 13.3 0.6 0.17 12.1 0.6 1.6 1 0 0 1 1 1 0 Calcium-binding EGF domain GTP_EFTU PF00009.27 KSA00177.1 - 3.9e-33 114.6 4.5 2.1e-31 109.0 4.5 2.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 KSA00177.1 - 4.6e-27 94.2 1.7 1.5e-26 92.5 1.7 2.0 1 0 0 1 1 1 1 Translation-initiation factor 2 IF2_N PF04760.15 KSA00177.1 - 5e-11 42.2 0.0 1.9e-10 40.4 0.0 2.1 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region MMR_HSR1 PF01926.23 KSA00177.1 - 9.8e-10 38.5 0.2 3.5e-09 36.7 0.2 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 KSA00177.1 - 0.0041 17.1 0.1 0.016 15.2 0.1 2.0 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain GTP_EFTU_D4 PF14578.6 KSA00177.1 - 0.0047 16.8 0.7 0.058 13.3 0.0 2.7 2 0 0 2 2 2 1 Elongation factor Tu domain 4 Ras PF00071.22 KSA00177.1 - 0.0078 15.8 0.2 0.022 14.3 0.2 1.8 1 0 0 1 1 1 1 Ras family FeoB_N PF02421.18 KSA00177.1 - 0.014 14.9 0.0 0.031 13.8 0.0 1.6 1 0 0 1 1 1 0 Ferrous iron transport protein B SRPRB PF09439.10 KSA00177.1 - 0.016 14.6 0.2 0.016 14.6 0.2 2.9 3 1 0 3 3 3 0 Signal recognition particle receptor beta subunit Ilar_coat PF01787.16 KSA00177.1 - 0.017 14.9 0.2 0.048 13.5 0.2 1.7 1 0 0 1 1 1 0 Ilarvirus coat protein GTP_EFTU_D2 PF03144.25 KSA00177.1 - 0.024 15.0 1.1 3.1 8.2 0.0 3.0 2 0 0 2 2 2 0 Elongation factor Tu domain 2 Dynamin_N PF00350.23 KSA00177.1 - 2.2 8.3 10.1 15 5.6 0.0 4.2 3 1 1 4 4 4 0 Dynamin family Dfp1_Him1_M PF08630.10 KSA00178.1 - 1.7e-35 122.0 1.8 5.7e-35 120.3 0.1 2.5 2 0 0 2 2 2 1 Dfp1/Him1, central region zf-DBF PF07535.12 KSA00178.1 - 5e-19 68.1 3.0 1.2e-18 66.9 3.0 1.7 1 0 0 1 1 1 1 DBF zinc finger SLM4 PF16818.5 KSA00179.1 - 4.1e-36 124.4 0.3 4.6e-36 124.2 0.3 1.0 1 0 0 1 1 1 1 Protein SLM4 UQ_con PF00179.26 KSA00180.1 - 1.6e-40 138.0 0.0 2.2e-40 137.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KSA00180.1 - 0.0079 15.9 0.0 0.023 14.4 0.0 1.7 1 1 0 1 1 1 1 Prokaryotic E2 family B CAF1A PF12253.8 KSA00180.1 - 5.2 7.3 19.8 9.7 6.5 19.8 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 subunit A Cwf_Cwc_15 PF04889.12 KSA00180.1 - 7.4 6.2 13.6 11 5.7 13.6 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SH3BGR PF04908.15 KSA00181.1 - 1.1e-08 35.2 0.0 2e-07 31.1 0.0 3.3 2 0 0 2 2 2 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.24 KSA00181.1 - 0.053 13.8 0.0 0.16 12.2 0.0 1.9 1 0 0 1 1 1 0 Glutaredoxin KH_1 PF00013.29 KSA00182.1 - 4.7e-74 244.2 44.6 1.3e-12 47.4 0.7 13.5 13 1 0 13 13 13 10 KH domain KH_4 PF13083.6 KSA00182.1 - 0.00022 21.0 8.4 2.1 8.3 0.0 5.9 5 0 0 5 5 5 3 KH domain MOEP19 PF16005.5 KSA00182.1 - 0.054 13.5 0.0 38 4.4 0.0 4.3 4 0 0 4 4 4 0 KH-like RNA-binding domain DUF3189 PF11385.8 KSA00182.1 - 0.12 12.2 0.2 17 5.2 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3189) AA_permease_2 PF13520.6 KSA00183.1 - 7.6e-86 288.6 42.2 9.3e-86 288.3 42.2 1.1 1 0 0 1 1 1 1 Amino acid permease L51_S25_CI-B8 PF05047.16 KSA00184.1 - 2.1e-05 24.3 0.0 3.5e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain PsaF PF17550.2 KSA00184.1 - 0.022 14.3 0.1 0.028 13.9 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function Zn_clus PF00172.18 KSA00185.1 - 0.0016 18.5 14.5 0.0029 17.7 14.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TauD PF02668.16 KSA00186.1 - 9.7e-59 199.3 1.4 1.3e-58 198.9 1.4 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family EF-hand_4 PF12763.7 KSA00187.1 - 1.1e-35 121.7 0.8 5.3e-12 45.6 0.4 4.1 4 0 0 4 4 4 3 Cytoskeletal-regulatory complex EF hand UBA PF00627.31 KSA00187.1 - 5.9e-10 38.8 0.8 1.7e-09 37.4 0.8 1.8 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_6 PF13405.6 KSA00187.1 - 2.1e-09 36.5 0.7 0.032 14.2 0.0 5.3 5 0 0 5 5 5 2 EF-hand domain EF-hand_1 PF00036.32 KSA00187.1 - 2.5e-08 32.9 0.1 0.54 9.9 0.0 5.4 5 0 0 5 5 5 2 EF hand DUF4201 PF13870.6 KSA00187.1 - 3.7e-06 26.8 39.0 0.0014 18.4 24.1 3.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4201) EF-hand_7 PF13499.6 KSA00187.1 - 4.3e-06 27.1 0.0 0.38 11.2 0.0 4.1 3 0 0 3 3 3 2 EF-hand domain pair TPR_MLP1_2 PF07926.12 KSA00187.1 - 0.00025 21.1 22.5 0.00025 21.1 22.5 3.2 1 1 1 2 2 2 1 TPR/MLP1/MLP2-like protein EzrA PF06160.12 KSA00187.1 - 0.0016 16.8 21.0 0.0016 16.8 21.0 3.2 2 1 0 3 3 3 1 Septation ring formation regulator, EzrA GAS PF13851.6 KSA00187.1 - 0.0031 16.9 42.7 0.18 11.2 25.1 3.9 1 1 3 4 4 4 2 Growth-arrest specific micro-tubule binding CUE PF02845.16 KSA00187.1 - 0.012 15.3 0.1 0.057 13.2 0.1 2.2 1 0 0 1 1 1 0 CUE domain MADF_DNA_bdg PF10545.9 KSA00187.1 - 0.058 13.7 0.2 0.058 13.7 0.2 2.7 2 0 0 2 2 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Abi_C PF14355.6 KSA00187.1 - 0.48 10.6 3.0 11 6.2 0.2 3.7 1 1 2 3 3 3 0 Abortive infection C-terminus Hanta_nucleocap PF00846.18 KSA00187.1 - 0.52 8.7 4.3 0.81 8.1 4.3 1.2 1 0 0 1 1 1 0 Hantavirus nucleocapsid protein MscS_porin PF12795.7 KSA00187.1 - 0.73 9.3 55.5 0.24 10.9 29.0 3.5 2 1 1 3 3 3 0 Mechanosensitive ion channel porin domain DUF1664 PF07889.12 KSA00187.1 - 1 9.4 24.1 8.4 6.5 10.1 3.7 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF4472 PF14739.6 KSA00187.1 - 4.9 7.9 36.5 3.9 8.3 7.5 4.2 1 1 1 3 3 3 0 Domain of unknown function (DUF4472) ADIP PF11559.8 KSA00187.1 - 5.2 7.1 46.6 5.4 7.1 9.3 4.1 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Wtap PF17098.5 KSA00187.1 - 5.7 6.9 37.7 1.4 8.8 30.1 3.6 2 1 1 3 3 3 0 WTAP/Mum2p family FUSC PF04632.12 KSA00187.1 - 6.9 5.1 6.6 11 4.4 6.6 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Spc7 PF08317.11 KSA00187.1 - 7.2 5.4 42.1 6 5.7 27.7 2.8 1 1 1 2 2 2 0 Spc7 kinetochore protein Gar1 PF04410.14 KSA00188.1 - 9e-41 139.2 0.0 1.1e-40 139.0 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region Sigma_reg_N PF13800.6 KSA00189.1 - 0.027 14.7 1.2 0.027 14.7 1.2 2.6 3 0 0 3 3 3 0 Sigma factor regulator N-terminal Peptidase_M1 PF01433.20 KSA00190.1 - 1.1e-77 260.5 0.5 1.1e-77 260.5 0.5 2.5 3 0 0 3 3 3 1 Peptidase family M1 domain ERAP1_C PF11838.8 KSA00190.1 - 1.3e-55 189.1 0.0 2.1e-55 188.5 0.0 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 KSA00190.1 - 1.5e-46 158.9 0.6 5.4e-46 157.1 0.2 2.1 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain Asn_synthase PF00733.21 KSA00191.1 - 3.6e-94 316.3 0.0 2.6e-52 178.6 0.0 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 KSA00191.1 - 2.9e-32 111.1 0.0 5.1e-32 110.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KSA00191.1 - 3.8e-26 91.9 0.0 7.7e-26 90.9 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 KSA00191.1 - 1.5e-05 24.6 0.0 2.8e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 KSA00191.1 - 0.17 11.0 0.0 0.28 10.3 0.0 1.3 1 0 0 1 1 1 0 NAD synthase CSN8_PSD8_EIF3K PF10075.9 KSA00192.1 - 3.6e-19 69.2 4.3 4e-19 69.0 1.8 2.1 2 0 0 2 2 2 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 KSA00192.1 - 0.00052 19.5 2.5 0.00088 18.8 2.5 1.3 1 0 0 1 1 1 1 SAC3/GANP family VPS28 PF03997.12 KSA00193.1 - 2e-65 220.0 1.5 2.5e-65 219.7 1.5 1.1 1 0 0 1 1 1 1 VPS28 protein Vps23_core PF09454.10 KSA00193.1 - 0.11 12.5 0.1 0.22 11.5 0.1 1.4 1 0 0 1 1 1 0 Vps23 core domain Syntaxin PF00804.25 KSA00195.1 - 6.9e-20 71.6 21.0 6.9e-20 71.6 21.0 1.8 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.19 KSA00195.1 - 3.3e-09 36.6 3.4 3.3e-09 36.6 3.4 2.6 2 1 0 2 2 2 1 SNARE domain Syntaxin_2 PF14523.6 KSA00195.1 - 0.005 17.2 26.0 0.0066 16.8 13.0 3.0 2 1 1 3 3 3 2 Syntaxin-like protein DUF745 PF05335.13 KSA00195.1 - 0.0053 16.5 5.2 0.0053 16.5 5.2 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF745) UPF0184 PF03670.13 KSA00195.1 - 0.013 15.8 1.8 0.013 15.8 1.8 3.1 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0184) T2SSF PF00482.23 KSA00195.1 - 0.018 15.0 1.3 0.027 14.4 0.2 1.9 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F COG2 PF06148.11 KSA00195.1 - 0.19 11.8 14.1 0.55 10.3 0.2 2.8 2 2 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 LMBR1 PF04791.16 KSA00195.1 - 0.24 10.3 9.1 0.33 9.8 9.1 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4094 PF13334.6 KSA00195.1 - 0.27 11.7 0.2 0.27 11.7 0.2 3.6 2 1 2 4 4 4 0 Domain of unknown function (DUF4094) Mobilization_B PF17511.2 KSA00195.1 - 0.33 11.3 5.4 1.8 8.9 0.2 2.6 2 1 0 2 2 2 0 Mobilization protein B DUF4199 PF13858.6 KSA00195.1 - 0.36 11.2 0.1 0.36 11.2 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF4199) Pox_EPC_I2-L1 PF12575.8 KSA00195.1 - 0.49 10.6 2.4 1.7 9.0 0.1 2.8 3 1 0 3 3 3 0 Poxvirus entry protein complex L1 and I2 T3SSipB PF16535.5 KSA00195.1 - 0.65 10.5 13.8 2.8 8.4 0.4 2.3 2 0 0 2 2 2 0 Type III cell invasion protein SipB SlyX PF04102.12 KSA00195.1 - 5.3 7.7 14.0 0.62 10.7 3.8 3.0 2 1 0 2 2 2 0 SlyX DUF1664 PF07889.12 KSA00195.1 - 6.1 6.9 15.5 5.5 7.1 1.9 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF2203 PF09969.9 KSA00195.1 - 9.3 7.0 15.2 2.4 8.9 2.2 2.8 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) IPK PF03770.16 KSA00196.1 - 2.1e-52 177.9 0.0 3.1e-52 177.3 0.0 1.3 1 0 0 1 1 1 1 Inositol polyphosphate kinase DUF5109 PF17134.4 KSA00196.1 - 0.089 12.7 0.1 0.2 11.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5109) GTP_EFTU PF00009.27 KSA00197.1 - 3.5e-43 147.4 0.0 7.3e-43 146.4 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KSA00197.1 - 5.9e-36 123.2 0.5 1.4e-35 122.0 0.5 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KSA00197.1 - 1.1e-07 32.1 0.3 3.7e-07 30.4 0.3 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KSA00197.1 - 0.0014 18.7 0.2 0.008 16.2 0.2 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase Retinal PF15449.6 KSA00197.1 - 0.054 11.3 18.0 0.08 10.7 18.0 1.2 1 0 0 1 1 1 0 Retinal protein Glyco_transf_15 PF01793.16 KSA00198.1 - 9e-61 205.9 8.0 1.2e-60 205.5 8.0 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase VHS PF00790.19 KSA00199.1 - 6.7e-11 42.2 0.0 1.2e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 KSA00199.1 - 0.0046 17.2 0.0 0.014 15.6 0.0 1.9 1 1 0 1 1 1 1 GAT domain Use1 PF09753.9 KSA00201.1 - 0.00073 19.3 0.0 0.00091 19.0 0.0 1.1 1 0 0 1 1 1 1 Membrane fusion protein Use1 ParA PF10609.9 KSA00202.1 - 1.8e-90 302.7 0.1 2.3e-90 302.4 0.1 1.2 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KSA00202.1 - 3.7e-08 33.5 0.0 5.4e-08 33.0 0.0 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 KSA00202.1 - 6.6e-06 26.1 0.1 2.4e-05 24.3 0.1 1.8 1 1 0 1 1 1 1 AAA domain MipZ PF09140.11 KSA00202.1 - 1.7e-05 24.2 0.2 8.5e-05 22.0 0.0 2.1 2 1 1 3 3 3 1 ATPase MipZ ArsA_ATPase PF02374.15 KSA00202.1 - 6.7e-05 22.2 0.3 0.00019 20.7 0.3 1.7 1 0 0 1 1 1 1 Anion-transporting ATPase Hpr_kinase_C PF07475.12 KSA00202.1 - 0.045 13.3 0.1 0.082 12.4 0.1 1.3 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain AAA_25 PF13481.6 KSA00202.1 - 0.059 12.9 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 KSA00202.1 - 0.075 12.9 0.1 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase MeaB PF03308.16 KSA00202.1 - 0.1 11.6 0.2 0.17 10.9 0.2 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Zn_Tnp_IS1595 PF12760.7 KSA00202.1 - 0.12 12.4 0.5 6.2 6.9 0.3 2.9 3 0 0 3 3 3 0 Transposase zinc-ribbon domain Nop16 PF09420.10 KSA00203.1 - 7.7e-62 209.0 11.3 9.9e-62 208.7 11.3 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 DUF4142 PF13628.6 KSA00203.1 - 0.03 14.5 1.4 0.068 13.4 1.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4142) Gluconate_2-dh3 PF13618.6 KSA00203.1 - 0.08 13.2 0.1 0.1 12.9 0.1 1.3 1 0 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 RRM_1 PF00076.22 KSA00204.1 - 2.5e-19 68.9 0.0 3.8e-19 68.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KSA00204.1 - 0.0005 19.7 0.0 0.00069 19.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WSD PF15613.6 KSA00204.1 - 0.021 15.3 0.5 2.4 8.7 0.4 2.3 2 0 0 2 2 2 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif RRM_occluded PF16842.5 KSA00204.1 - 0.058 13.3 0.0 0.085 12.7 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif GRP PF07172.11 KSA00204.1 - 0.31 11.7 12.8 0.052 14.2 7.9 2.0 2 0 0 2 2 2 0 Glycine rich protein family PMI_typeI PF01238.21 KSA00205.1 - 5.2e-149 496.5 0.0 6.1e-149 496.3 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I FliG_N PF14842.6 KSA00205.1 - 0.039 14.5 0.0 0.086 13.4 0.0 1.5 1 0 0 1 1 1 0 FliG N-terminal domain Hexapep PF00132.24 KSA00206.1 - 5.7e-06 25.8 6.9 0.58 10.0 0.0 4.6 4 1 0 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Thioredoxin PF00085.20 KSA00207.1 - 7.8e-20 70.8 0.9 9.1e-16 57.7 0.0 3.4 3 1 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 KSA00207.1 - 6.7e-07 29.4 6.8 3.8e-05 23.7 6.1 3.3 1 1 3 4 4 4 1 Thioredoxin-like domain Mito_carr PF00153.27 KSA00208.1 - 2.3e-71 235.8 5.2 8.2e-24 83.4 0.2 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF866 PF05907.13 KSA00209.1 - 3.4e-61 205.7 1.1 3.8e-61 205.5 1.1 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Zn_ribbon_SprT PF17283.2 KSA00209.1 - 0.018 15.0 0.7 0.039 13.8 0.7 1.6 1 1 0 1 1 1 0 SprT-like zinc ribbon domain Ribosomal_L44 PF00935.19 KSA00209.1 - 0.029 14.8 1.6 1.6 9.3 0.2 2.2 2 0 0 2 2 2 0 Ribosomal protein L44 RNHCP PF12647.7 KSA00209.1 - 0.085 12.8 0.3 6.3 6.9 0.1 2.3 1 1 1 2 2 2 0 RNHCP domain Mito_carr PF00153.27 KSA00210.1 - 3e-40 136.0 6.1 2e-14 53.3 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein LGT PF01790.18 KSA00210.1 - 0.019 14.2 0.0 0.031 13.5 0.0 1.2 1 0 0 1 1 1 0 Prolipoprotein diacylglyceryl transferase ArfGap PF01412.18 KSA00211.1 - 1.2e-39 135.0 3.5 1.2e-39 135.0 3.5 1.9 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf Nitr_red_assoc PF09655.10 KSA00211.1 - 0.28 11.8 2.3 0.36 11.5 0.2 2.2 3 0 0 3 3 3 0 Conserved nitrate reductase-associated protein (Nitr_red_assoc) Cyt-b5 PF00173.28 KSA00212.1 - 3.7e-21 75.1 0.0 5.5e-21 74.5 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Smim3 PF17307.2 KSA00212.1 - 0.059 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Small integral membrane protein 3 Med5 PF08689.10 KSA00213.1 - 3e-60 204.2 39.8 7.4e-60 202.9 39.8 1.5 1 1 0 1 1 1 1 Mediator complex subunit Med5 RskA PF10099.9 KSA00214.1 - 0.0024 18.2 0.3 0.005 17.2 0.3 1.5 1 0 0 1 1 1 1 Anti-sigma-K factor rskA Phostensin_N PF13916.6 KSA00214.1 - 0.87 10.0 5.1 1.8 9.0 5.1 1.6 1 0 0 1 1 1 0 PP1-regulatory protein, Phostensin N-terminal ALMT PF11744.8 KSA00214.1 - 1.4 7.7 7.4 2.1 7.1 7.4 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Pex14_N PF04695.13 KSA00215.1 - 1.2e-37 130.0 1.5 1.2e-37 130.0 1.5 3.5 2 1 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Cofilin_ADF PF00241.20 KSA00215.1 - 0.0044 16.8 1.3 0.011 15.6 0.3 2.2 2 0 0 2 2 2 1 Cofilin/tropomyosin-type actin-binding protein LidA_Long_CC PF18641.1 KSA00215.1 - 0.016 15.2 6.1 0.016 15.2 6.1 3.4 3 1 1 4 4 4 0 LidA long coiled-coil domain CR6_interact PF10147.9 KSA00215.1 - 0.088 12.5 0.1 0.088 12.5 0.1 2.8 2 1 1 3 3 3 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 COMP PF11598.8 KSA00215.1 - 0.28 11.7 1.2 6.3 7.4 0.5 2.4 2 0 0 2 2 2 0 Cartilage oligomeric matrix protein DUF1664 PF07889.12 KSA00215.1 - 0.44 10.6 5.6 3.9 7.5 2.8 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Mito_carr PF00153.27 KSA00216.1 - 1.3e-45 153.2 1.3 3.3e-15 55.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Prenyltrans PF00432.21 KSA00217.1 - 1.1e-25 89.1 0.6 1.2e-07 31.3 0.1 5.7 5 1 0 5 5 5 4 Prenyltransferase and squalene oxidase repeat Presenilin PF01080.17 KSA00218.1 - 0.14 10.9 3.9 0.15 10.8 3.9 1.1 1 0 0 1 1 1 0 Presenilin Hid1 PF12722.7 KSA00218.1 - 6.5 4.8 9.2 7.3 4.6 9.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Plasmodium_Vir PF05795.11 KSA00218.1 - 9.6 5.5 9.7 11 5.3 9.7 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein ACPS PF01648.20 KSA00219.1 - 6.8e-09 35.9 0.1 2.2e-08 34.2 0.0 1.9 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily Beta_elim_lyase PF01212.21 KSA00220.1 - 1.5e-76 257.5 0.0 1.8e-76 257.2 0.0 1.0 1 0 0 1 1 1 1 Beta-eliminating lyase Aldedh PF00171.22 KSA00221.1 - 5.3e-180 598.8 0.1 6e-180 598.7 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KSA00221.1 - 5.2e-05 22.5 0.1 7.8e-05 21.9 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) Endonuc_subdom PF09062.10 KSA00221.1 - 0.1 13.4 0.2 0.2 12.5 0.2 1.4 1 0 0 1 1 1 0 PI-PfuI Endonuclease subdomain F-box-like PF12937.7 KSA00222.1 - 1.8e-07 31.0 0.3 1.4e-06 28.1 0.1 2.6 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KSA00222.1 - 0.00025 20.8 0.0 0.00093 19.0 0.0 2.0 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KSA00222.1 - 0.00028 20.8 0.0 0.0011 18.9 0.0 2.0 1 0 0 1 1 1 1 F-box LisH PF08513.11 KSA00224.1 - 0.00068 19.5 0.8 0.0014 18.5 0.8 1.5 1 0 0 1 1 1 1 LisH Vezatin PF12632.7 KSA00225.1 - 2.9e-51 174.5 19.6 2.9e-51 174.5 19.6 3.0 3 1 0 3 3 3 1 Mysoin-binding motif of peroxisomes SNF2_N PF00176.23 KSA00226.1 - 3.4e-66 223.4 0.3 6.2e-66 222.5 0.3 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.6 KSA00226.1 - 2.9e-48 163.6 20.4 2.9e-48 163.6 20.4 3.1 3 1 0 3 3 3 1 DNA-binding domain Helicase_C PF00271.31 KSA00226.1 - 8.5e-18 64.7 0.0 3.5e-17 62.8 0.0 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain pP_pnuc_2 PF18166.1 KSA00226.1 - 0.093 12.8 1.4 17 5.5 0.0 2.8 2 0 0 2 2 2 0 Predicted pPIWI-associating nuclease Fe_hyd_lg_C PF02906.14 KSA00226.1 - 0.21 11.3 3.9 0.075 12.7 0.2 2.1 2 0 0 2 2 2 0 Iron only hydrogenase large subunit, C-terminal domain Colicin_E5 PF12106.8 KSA00226.1 - 0.32 11.3 4.2 1.2 9.5 0.1 2.9 2 0 0 2 2 2 0 Colicin E5 ribonuclease domain Tmemb_14 PF03647.13 KSA00227.1 - 1.4e-23 83.4 6.0 1.6e-23 83.2 6.0 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C Ribosomal_S3_C PF00189.20 KSA00228.1 - 4.3e-23 81.6 0.4 2e-22 79.5 0.3 2.1 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 KSA00228.1 - 6.4e-09 35.5 0.6 1.2e-08 34.6 0.6 1.5 1 0 0 1 1 1 1 KH domain GATase_5 PF13507.6 KSA00229.1 - 5.5e-107 356.7 0.0 9e-107 356.0 0.0 1.4 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 KSA00229.1 - 1.1e-34 119.8 0.3 1.5e-27 96.7 0.1 2.4 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 KSA00229.1 - 8.8e-26 90.2 0.0 1.7e-25 89.3 0.0 1.5 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 KSA00229.1 - 4e-22 78.5 0.0 1.3e-21 76.9 0.0 1.9 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain DUF2462 PF09495.10 KSA00230.1 - 1.9e-16 60.5 10.3 1.9e-16 60.5 10.3 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2462) MFS_1 PF07690.16 KSA00232.1 - 5.7e-09 35.4 21.2 6.5e-09 35.2 18.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily PRD1_DD PF11087.8 KSA00232.1 - 0.036 13.8 0.1 0.11 12.2 0.1 1.8 1 0 0 1 1 1 0 PRD1 phage membrane DNA delivery DUF366 PF04017.12 KSA00232.1 - 0.094 12.2 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF366) Baculo_11_kDa PF06143.11 KSA00233.1 - 0.0025 17.3 0.9 0.42 10.2 0.1 2.3 2 0 0 2 2 2 2 Baculovirus 11 kDa family SARAF PF06682.12 KSA00233.1 - 0.0037 17.0 0.4 0.012 15.3 0.1 1.7 1 1 1 2 2 2 2 SOCE-associated regulatory factor of calcium homoeostasis ISK_Channel PF02060.15 KSA00233.1 - 0.016 14.9 0.1 0.69 9.7 0.1 2.1 2 0 0 2 2 2 0 Slow voltage-gated potassium channel MAP17 PF15807.5 KSA00233.1 - 0.052 13.8 0.9 3.1 8.1 0.1 2.5 1 1 2 3 3 3 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DUF2633 PF11119.8 KSA00233.1 - 0.18 11.7 2.1 0.94 9.4 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2633) RNA_pol_Rpb8 PF03870.15 KSA00234.1 - 2.4e-45 154.1 0.2 2.7e-45 154.0 0.2 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 KSA00234.1 - 1.3e-06 28.4 0.6 0.039 14.0 0.1 2.1 2 0 0 2 2 2 2 DNA-directed RNA polymerase, subunit G XPG_N PF00752.17 KSA00235.1 - 0.0013 19.2 0.0 0.0015 19.0 0.0 1.1 1 0 0 1 1 1 1 XPG N-terminal domain UPF0242 PF06785.11 KSA00236.1 - 3.6 7.7 12.6 4.6 7.3 12.6 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus KilA-N PF04383.13 KSA00237.1 - 2.4e-05 24.1 0.0 0.00027 20.7 0.0 2.3 1 1 0 1 1 1 1 KilA-N domain WBS_methylT PF12589.8 KSA00237.1 - 0.98 10.2 3.3 4.8 8.0 3.3 2.2 1 0 0 1 1 1 0 Methyltransferase involved in Williams-Beuren syndrome Bap31 PF05529.12 KSA00238.1 - 8.8e-34 116.3 6.4 1.1e-33 115.9 6.4 1.1 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 KSA00238.1 - 1.4e-09 37.8 0.7 1.4e-09 37.8 0.7 1.9 3 0 0 3 3 3 1 Bap31/Bap29 cytoplasmic coiled-coil domain CorA PF01544.18 KSA00239.1 - 1.4e-38 132.9 2.4 1.1e-19 70.9 0.1 3.4 3 0 0 3 3 3 3 CorA-like Mg2+ transporter protein PC4 PF02229.16 KSA00240.1 - 7.1e-21 73.6 0.9 1.1e-20 73.0 0.9 1.3 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) Aldo_ket_red PF00248.21 KSA00241.1 - 1.5e-44 152.3 0.0 1.8e-44 152.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family FSH1 PF03959.13 KSA00241.1 - 0.13 11.9 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) FCH PF00611.23 KSA00242.1 - 3.7e-11 43.2 0.6 3.7e-11 43.2 0.6 2.4 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 KSA00242.1 - 2.3e-08 33.5 0.0 5.7e-08 32.2 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KSA00242.1 - 1.6e-07 31.0 0.0 3.2e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KSA00242.1 - 0.00025 20.7 0.0 0.00055 19.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain IFR3_antag PF14754.6 KSA00242.1 - 0.2 10.8 0.0 0.32 10.2 0.0 1.2 1 0 0 1 1 1 0 Papain-like auto-proteinase DUF4298 PF14131.6 KSA00242.1 - 0.86 9.6 15.3 1.4 8.9 3.4 4.1 3 1 1 4 4 4 0 Domain of unknown function (DUF4298) TSP_NTD PF17804.1 KSA00242.1 - 0.99 9.6 13.4 0.58 10.4 10.2 2.1 1 1 0 2 2 2 0 Tail specific protease N-terminal domain YabA PF06156.13 KSA00242.1 - 4.8 7.9 11.2 1.2 9.9 0.5 2.9 1 1 1 2 2 2 0 Initiation control protein YabA SBF_like PF13593.6 KSA00243.1 - 8.9e-123 409.6 15.2 1e-122 409.4 15.2 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) Colicin_im PF03857.13 KSA00243.1 - 0.0011 19.0 4.3 0.0032 17.4 4.3 1.7 1 0 0 1 1 1 1 Colicin immunity protein KdgT PF03812.13 KSA00243.1 - 0.013 14.8 4.0 0.013 14.8 4.0 2.4 2 1 0 2 2 2 0 2-keto-3-deoxygluconate permease Hyphal_reg_CWP PF11765.8 KSA00244.1 - 1.3e-07 30.9 0.2 1.4e-07 30.8 0.2 1.0 1 0 0 1 1 1 1 Hyphally regulated cell wall protein N-terminal Cyclin_N PF00134.23 KSA00245.1 - 3e-38 130.4 0.5 2.2e-37 127.6 0.1 2.4 3 0 0 3 3 3 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KSA00245.1 - 7.6e-09 35.7 0.3 2.3e-08 34.1 0.3 1.8 1 0 0 1 1 1 1 Cyclin, C-terminal domain PI3_PI4_kinase PF00454.27 KSA00246.1 - 2.9e-33 115.7 0.1 4.8e-32 111.7 0.0 2.9 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.8 KSA00246.1 - 1.3e-19 69.9 0.5 3.7e-19 68.4 0.5 1.9 1 0 0 1 1 1 1 Yeast phosphatidylinositol-4-OH kinase Pik1 PI3Ka PF00613.20 KSA00246.1 - 7.1e-06 25.5 3.3 1.9e-05 24.1 3.3 1.8 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF4135 PF13575.6 KSA00246.1 - 0.01 15.2 0.1 0.036 13.4 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4135) Oxysterol_BP PF01237.18 KSA00247.1 - 2.7e-86 289.7 0.0 1.7e-83 280.5 0.0 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein PAP_central PF04928.17 KSA00248.1 - 1.6e-112 374.5 0.0 3.1e-112 373.5 0.0 1.5 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 KSA00248.1 - 1.4e-58 197.3 0.9 3.4e-58 196.0 0.9 1.7 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 KSA00248.1 - 1.7e-12 47.4 0.0 1.7e-12 47.4 0.0 2.3 3 0 0 3 3 3 1 Nucleotidyltransferase domain Polbeta PF18765.1 KSA00248.1 - 0.0085 16.2 0.0 0.036 14.2 0.0 2.0 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase Nrap_D2 PF17403.2 KSA00248.1 - 0.018 14.8 0.1 0.035 13.9 0.1 1.5 1 0 0 1 1 1 0 Nrap protein PAP/OAS-like domain AA_permease PF00324.21 KSA00249.1 - 4.9e-141 470.6 41.8 5.6e-141 470.4 41.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KSA00249.1 - 2.6e-45 155.0 43.8 3.5e-45 154.6 43.8 1.1 1 0 0 1 1 1 1 Amino acid permease Exo_endo_phos PF03372.23 KSA00250.1 - 0.00094 18.8 0.0 0.0026 17.3 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF3449 PF11931.8 KSA00251.1 - 9.7e-63 211.3 0.3 9.7e-63 211.3 0.3 2.7 3 1 0 3 3 3 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 KSA00251.1 - 1.1e-17 64.3 6.4 1.1e-17 64.3 6.4 2.0 2 0 0 2 2 2 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 PRP9_N PF16958.5 KSA00251.1 - 8.7e-17 61.5 16.6 1.1e-14 54.7 16.6 3.2 1 1 0 1 1 1 1 Pre-mRNA-splicing factor PRP9 N-terminus zf-met PF12874.7 KSA00251.1 - 5.2e-15 55.3 7.2 2.7e-07 30.7 0.8 3.5 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KSA00251.1 - 1.1e-10 41.5 12.2 1.3e-07 31.8 1.0 3.7 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-DBF PF07535.12 KSA00251.1 - 0.0012 18.9 8.0 0.004 17.2 1.0 2.8 2 0 0 2 2 2 1 DBF zinc finger zf-U1 PF06220.12 KSA00251.1 - 0.0019 17.9 1.2 0.0019 17.9 1.2 2.2 2 0 0 2 2 2 1 U1 zinc finger zf-C2H2_2 PF12756.7 KSA00251.1 - 0.049 14.0 10.5 0.44 10.9 0.1 3.9 3 1 0 3 3 3 0 C2H2 type zinc-finger (2 copies) Desulfoferrod_N PF06397.12 KSA00251.1 - 0.28 10.8 1.1 0.65 9.7 1.1 1.5 1 0 0 1 1 1 0 Desulfoferrodoxin, N-terminal domain Inv-AAD PF18785.1 KSA00252.1 - 3.3e-36 124.0 0.1 5.5e-36 123.3 0.1 1.4 1 0 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase PseudoU_synth_2 PF00849.22 KSA00252.1 - 3.6e-32 111.7 0.0 6.4e-32 110.9 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase dCMP_cyt_deam_1 PF00383.23 KSA00252.1 - 5.1e-20 71.2 0.1 1.2e-19 70.1 0.1 1.5 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KSA00252.1 - 4.9e-06 26.3 0.0 8.4e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 MafB19-like deaminase S4 PF01479.25 KSA00252.1 - 0.13 12.0 0.8 0.25 11.1 0.0 1.9 2 0 0 2 2 2 0 S4 domain PalH PF08733.10 KSA00253.1 - 9.3e-83 278.0 18.8 9.3e-83 278.0 18.8 1.4 2 0 0 2 2 2 1 PalH/RIM21 DUF4407 PF14362.6 KSA00253.1 - 2.1 7.6 5.7 17 4.6 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF418 PF04235.12 KSA00253.1 - 7.1 6.5 11.2 0.32 10.9 0.3 2.9 1 1 1 3 3 3 0 Protein of unknown function (DUF418) RabGAP-TBC PF00566.18 KSA00254.1 - 7.9e-38 130.3 0.4 2.8e-37 128.5 0.4 1.9 1 1 0 1 1 1 1 Rab-GTPase-TBC domain HECW1_helix PF18436.1 KSA00254.1 - 0.083 13.0 0.4 0.24 11.6 0.4 1.8 1 0 0 1 1 1 0 Helical box domain of E3 ubiquitin-protein ligase HECW1 HSF_DNA-bind PF00447.17 KSA00254.1 - 0.12 13.0 2.1 0.17 12.6 0.3 2.1 2 0 0 2 2 2 0 HSF-type DNA-binding Get5_bdg PF16843.5 KSA00255.1 - 0.0084 15.6 0.0 0.017 14.6 0.0 1.5 1 0 0 1 1 1 1 Binding domain to Get4 on Get5, Golgi to ER traffic protein DUF2407 PF10302.9 KSA00255.1 - 0.013 16.1 0.0 0.025 15.1 0.0 1.6 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 KSA00255.1 - 0.021 14.9 0.3 0.039 14.0 0.0 1.5 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like SPOR PF05036.13 KSA00255.1 - 0.11 12.9 0.0 0.22 11.9 0.0 1.5 1 0 0 1 1 1 0 Sporulation related domain Got1 PF04178.12 KSA00256.1 - 2.2e-32 111.8 19.9 2.9e-32 111.4 19.9 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family DUF2070 PF09843.9 KSA00256.1 - 0.0024 16.2 12.5 0.003 15.9 12.5 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2070) TLD PF07534.16 KSA00258.1 - 1.4e-25 90.1 2.3 1.3e-22 80.5 1.0 2.7 2 1 0 2 2 2 2 TLD Adeno_E1A PF02703.14 KSA00258.1 - 0.044 13.4 0.6 0.065 12.8 0.6 1.2 1 0 0 1 1 1 0 Early E1A protein M-factor PF03855.13 KSA00258.1 - 0.16 12.1 0.8 0.5 10.6 0.8 1.8 1 0 0 1 1 1 0 M-factor Bundlin PF05307.11 KSA00258.1 - 9.9 6.1 7.1 43 4.1 0.4 3.3 2 1 1 3 3 3 0 Bundlin Asp_Glu_race PF01177.22 KSA00259.1 - 4.9e-06 26.6 0.0 7.1e-06 26.0 0.0 1.3 1 1 0 1 1 1 1 Asp/Glu/Hydantoin racemase Rad9 PF04139.13 KSA00260.1 - 6.7e-14 51.9 13.9 1.6e-11 44.1 13.9 3.0 1 1 0 1 1 1 1 Rad9 MPC PF03650.13 KSA00261.1 - 1.3e-36 125.0 0.0 1.5e-36 124.9 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers Zn_clus PF00172.18 KSA00262.1 - 9.4e-06 25.7 18.0 1.8e-05 24.7 18.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain bZIP_1 PF00170.21 KSA00262.1 - 0.053 13.6 2.9 0.21 11.7 2.9 2.1 1 0 0 1 1 1 0 bZIP transcription factor Nup54 PF13874.6 KSA00262.1 - 2.5 8.2 9.2 0.85 9.7 1.5 3.2 3 0 0 3 3 3 0 Nucleoporin complex subunit 54 APG6_N PF17675.1 KSA00262.1 - 3.4 8.2 12.6 1.3 9.5 1.3 3.5 3 0 0 3 3 3 0 Apg6 coiled-coil region Ax_dynein_light PF10211.9 KSA00262.1 - 3.7 7.5 11.2 4.4 7.2 0.4 2.8 2 0 0 2 2 2 0 Axonemal dynein light chain THOC7 PF05615.13 KSA00262.1 - 4.5 7.6 7.9 4.5 7.6 1.9 3.0 3 0 0 3 3 3 0 Tho complex subunit 7 DJ-1_PfpI PF01965.24 KSA00264.1 - 2.7e-10 40.3 0.0 8.5e-10 38.7 0.0 1.8 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 KSA00264.1 - 7.5e-07 29.0 0.2 1e-05 25.3 0.2 2.0 1 1 0 1 1 1 1 ThiJ/PfpI family-like CAP_C PF08603.11 KSA00264.1 - 0.046 13.3 0.0 0.069 12.8 0.0 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) C terminal Acyltransferase PF01553.21 KSA00265.1 - 8.6e-33 112.8 0.0 1.6e-32 112.0 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Amelotin PF15757.5 KSA00265.1 - 0.061 12.9 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Amelotin Adaptin_N PF01602.20 KSA00266.1 - 9.9e-93 311.5 31.6 2.1e-92 310.4 31.6 1.4 1 1 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KSA00266.1 - 1.9e-10 41.0 6.6 7.2e-10 39.1 1.4 2.9 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 DBD_HTH PF18430.1 KSA00266.1 - 0.00063 19.5 2.3 0.021 14.6 0.2 2.8 2 0 0 2 2 2 1 Putative DNA-binding domain Vac14_Fab1_bd PF12755.7 KSA00266.1 - 0.15 12.7 2.8 4 8.1 0.2 3.3 2 1 1 3 3 3 0 Vacuolar 14 Fab1-binding region KxDL PF10241.9 KSA00267.1 - 4.7e-07 30.0 5.8 9.7e-07 29.0 3.5 2.6 2 1 0 2 2 2 1 Uncharacterized conserved protein HMMR_C PF15908.5 KSA00267.1 - 0.021 15.1 1.9 0.034 14.4 1.9 1.3 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor C-terminal DUF1664 PF07889.12 KSA00267.1 - 0.089 12.8 1.8 0.38 10.8 1.8 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Metallopep PF12044.8 KSA00268.1 - 1.5e-167 557.5 0.0 1.9e-167 557.2 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Jacalin PF01419.17 KSA00268.1 - 2.4e-05 24.3 0.1 6.2e-05 22.9 0.1 1.8 1 0 0 1 1 1 1 Jacalin-like lectin domain Reprolysin_3 PF13582.6 KSA00268.1 - 0.0084 16.6 1.1 0.05 14.1 0.2 2.4 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KSA00268.1 - 0.0094 16.1 1.2 0.014 15.6 0.1 1.8 2 0 0 2 2 2 1 Metallo-peptidase family M12 Peptidase_M66 PF10462.9 KSA00268.1 - 0.076 11.9 0.0 0.15 11.0 0.0 1.4 1 0 0 1 1 1 0 Peptidase M66 DUF4145 PF13643.6 KSA00268.1 - 0.12 12.5 0.4 0.33 11.1 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4145) Tyr-DNA_phospho PF06087.12 KSA00269.1 - 2.6e-16 59.6 0.2 4.7e-16 58.7 0.2 1.4 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase Tyr-DNA_phospho PF06087.12 KSA00270.1 - 4.8e-78 262.9 0.2 5.4e-78 262.8 0.2 1.0 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.6 KSA00270.1 - 0.004 17.0 0.0 0.0067 16.3 0.0 1.3 1 0 0 1 1 1 1 PLD-like domain CEL_III_C PF18054.1 KSA00270.1 - 0.14 12.2 0.3 16 5.6 0.0 2.2 2 0 0 2 2 2 0 CEL-III C-terminal SMC_N PF02463.19 KSA00271.1 - 1.4e-63 214.3 26.6 3.7e-63 212.9 26.6 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KSA00271.1 - 7.9e-30 103.6 0.1 6.6e-29 100.6 0.0 2.7 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KSA00271.1 - 4.5e-14 53.0 0.8 8.6e-09 35.6 0.4 4.7 3 2 1 4 4 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KSA00271.1 - 3.6e-10 40.1 27.5 3.6e-10 40.1 27.5 4.4 2 2 2 4 4 3 2 AAA ATPase domain AAA_23 PF13476.6 KSA00271.1 - 4.6e-08 33.8 35.3 4.6e-08 33.8 35.3 7.7 2 2 2 4 4 1 1 AAA domain FtsK_SpoIIIE PF01580.18 KSA00271.1 - 0.0038 16.6 3.8 0.013 14.8 0.0 3.4 3 0 0 3 3 3 1 FtsK/SpoIIIE family Tropomyosin PF00261.20 KSA00271.1 - 0.0048 16.3 8.7 0.0048 16.3 8.7 6.9 3 2 1 5 5 5 1 Tropomyosin AAA_29 PF13555.6 KSA00271.1 - 0.0087 15.8 0.0 0.019 14.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain BRCT PF00533.26 KSA00271.1 - 0.029 14.7 0.2 1.4 9.3 0.0 3.9 3 0 0 3 3 3 0 BRCA1 C Terminus (BRCT) domain TFA2_Winged_2 PF18121.1 KSA00271.1 - 0.11 12.2 5.7 0.12 12.0 0.3 3.8 3 0 0 3 3 3 0 TFA2 Winged helix domain 2 MCPVI PF02993.14 KSA00271.1 - 9 6.0 7.9 2.7 7.8 0.8 3.0 2 0 0 2 2 2 0 Minor capsid protein VI FA_desaturase PF00487.24 KSA00272.1 - 1.4e-28 100.5 21.6 1.9e-28 100.0 21.6 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 KSA00272.1 - 1.3e-11 44.5 0.1 2.9e-11 43.4 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NUFIP1 PF10453.9 KSA00273.1 - 7.1e-17 61.0 9.5 7.1e-17 61.0 9.5 2.5 1 1 1 2 2 2 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-CCCH_4 PF18044.1 KSA00273.1 - 6.6e-05 22.6 4.3 9.8e-05 22.1 4.3 1.3 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KSA00273.1 - 0.00046 20.2 8.6 0.00073 19.5 8.6 1.3 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 KSA00273.1 - 0.00061 19.6 2.3 0.00098 19.0 2.3 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) ANAPC_CDC26 PF10471.9 KSA00273.1 - 0.0016 19.3 0.6 0.0016 19.3 0.6 2.3 2 1 0 2 2 2 1 Anaphase-promoting complex APC subunit CDC26 zf-CCCH_2 PF14608.6 KSA00273.1 - 1.5 9.4 6.8 3 8.4 6.8 1.6 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger tRNA-synt_2b PF00587.25 KSA00274.1 - 2.4e-33 115.6 0.2 6.7e-33 114.2 0.0 1.8 2 1 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 KSA00274.1 - 3.8e-22 78.6 10.3 5.5e-22 78.0 8.6 2.0 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain DUF3698 PF12479.8 KSA00274.1 - 0.038 14.5 0.9 0.12 12.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3698) HBM PF16591.5 KSA00274.1 - 0.04 13.3 2.1 0.095 12.1 2.1 1.6 1 0 0 1 1 1 0 Helical bimodular sensor domain NPV_P10 PF05531.12 KSA00274.1 - 1.2 9.7 4.3 2 8.9 1.9 2.6 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein WD40 PF00400.32 KSA00275.1 - 2.4e-19 69.3 18.9 1.9e-05 25.3 0.6 5.5 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KSA00275.1 - 5.4e-10 39.4 0.2 0.61 10.4 0.0 5.2 3 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Mu-transpos_C PF09299.11 KSA00275.1 - 0.18 11.8 0.0 29 4.7 0.1 2.7 2 0 0 2 2 2 0 Mu transposase, C-terminal Cytokin_check_N PF10407.9 KSA00276.1 - 4.3e-27 93.9 0.1 1.3e-26 92.3 0.1 2.0 1 0 0 1 1 1 1 Cdc14 phosphatase binding protein N-terminus Ribonuclease_3 PF00636.26 KSA00277.1 - 0.00046 20.8 0.0 0.0011 19.6 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease III domain Tcp11 PF05794.13 KSA00278.1 - 6.9e-138 460.4 3.7 9.9e-138 459.9 3.7 1.2 1 0 0 1 1 1 1 T-complex protein 11 MMR_HSR1_Xtn PF16897.5 KSA00279.1 - 0.21 11.6 0.2 0.21 11.6 0.2 1.9 2 1 0 2 2 2 0 C-terminal region of MMR_HSR1 domain Glyco_hydro_92 PF07971.12 KSA00281.1 - 2.2e-144 481.8 8.7 3.2e-144 481.3 8.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 KSA00281.1 - 8.7e-54 182.9 5.9 8.7e-54 182.9 5.9 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 92 N-terminal domain Pkinase PF00069.25 KSA00282.1 - 5.2e-46 157.1 0.0 8.6e-46 156.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KSA00282.1 - 2.7e-25 89.1 0.0 3.9e-25 88.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KSA00282.1 - 0.0014 18.0 0.0 0.003 16.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KSA00282.1 - 0.034 13.5 0.0 0.057 12.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KSA00283.1 - 9.2e-75 251.4 0.0 1e-74 251.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KSA00283.1 - 1.8e-30 106.1 0.0 2.2e-30 105.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KSA00283.1 - 2.3e-05 23.5 0.1 0.00019 20.5 0.1 2.0 1 1 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 KSA00283.1 - 0.00043 19.4 0.1 0.0007 18.8 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Kinase-like PF14531.6 KSA00283.1 - 0.00047 19.6 0.0 0.00084 18.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KSA00283.1 - 0.0014 18.6 0.1 0.0055 16.6 0.1 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KSA00283.1 - 0.0037 16.6 0.1 0.0097 15.3 0.1 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Lge1 PF11488.8 KSA00285.1 - 1.1e-15 57.6 3.1 1.7e-15 57.0 3.1 1.3 1 0 0 1 1 1 1 Transcriptional regulatory protein LGE1 adh_short PF00106.25 KSA00286.1 - 1e-33 116.4 0.3 1.4e-33 116.0 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KSA00286.1 - 6.7e-19 68.4 0.0 9.2e-19 67.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KSA00286.1 - 0.0012 18.8 0.1 0.014 15.3 0.0 2.1 2 0 0 2 2 2 1 KR domain DnaJ_C PF01556.18 KSA00287.1 - 1.3e-34 119.4 0.0 1.7e-34 119.1 0.0 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KSA00287.1 - 6.2e-24 83.9 0.4 9.1e-24 83.4 0.4 1.2 1 0 0 1 1 1 1 DnaJ domain WD40 PF00400.32 KSA00288.1 - 9.2e-41 137.1 20.5 2e-08 34.7 0.0 8.1 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KSA00288.1 - 3.6e-13 49.6 4.2 0.0059 16.9 0.1 5.2 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KSA00288.1 - 4.5e-08 32.2 11.7 0.019 13.7 0.3 4.7 3 1 1 5 5 5 4 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KSA00288.1 - 4.6e-06 25.8 0.4 0.048 12.6 0.0 3.6 2 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein VID27 PF08553.10 KSA00288.1 - 0.00059 19.0 0.0 0.17 10.9 0.0 2.4 1 1 0 2 2 2 2 VID27 C-terminal WD40-like domain PALB2_WD40 PF16756.5 KSA00288.1 - 0.00078 18.5 3.8 0.0013 17.8 0.0 2.8 4 0 0 4 4 4 1 Partner and localizer of BRCA2 WD40 domain Nucleoporin_N PF08801.11 KSA00288.1 - 0.0046 15.8 0.2 0.2 10.4 0.0 3.2 1 1 1 2 2 2 1 Nup133 N terminal like Frtz PF11768.8 KSA00288.1 - 0.0085 14.5 0.1 0.035 12.4 0.0 1.9 2 0 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz Hira PF07569.11 KSA00288.1 - 0.017 14.9 4.8 1.6 8.4 0.1 3.7 2 1 3 5 5 5 0 TUP1-like enhancer of split WD40_3 PF15911.5 KSA00288.1 - 0.045 13.8 0.3 14 5.8 0.1 2.9 3 0 0 3 3 3 0 WD domain, G-beta repeat BBS2_Mid PF14783.6 KSA00288.1 - 0.048 13.7 0.1 3.5 7.7 0.0 3.7 4 1 1 5 5 5 0 Ciliary BBSome complex subunit 2, middle region SET PF00856.28 KSA00289.1 - 0.0049 17.3 2.8 0.0053 17.1 0.8 2.1 2 1 0 2 2 2 1 SET domain Arena_ncap_C PF17290.2 KSA00289.1 - 0.042 13.2 0.0 0.11 11.8 0.0 1.7 1 0 0 1 1 1 0 Arenavirus nucleocapsid C-terminal domain RFX_DNA_binding PF02257.15 KSA00290.1 - 2.9e-33 114.3 0.0 8.8e-33 112.8 0.0 1.8 1 0 0 1 1 1 1 RFX DNA-binding domain Pox_D5 PF03288.16 KSA00290.1 - 0.025 15.1 0.0 0.14 12.6 0.0 2.3 1 0 0 1 1 1 0 Poxvirus D5 protein-like BssS PF13991.6 KSA00290.1 - 0.029 14.4 0.0 0.085 12.9 0.0 1.7 1 0 0 1 1 1 0 BssS protein family GED PF02212.18 KSA00290.1 - 0.073 13.2 0.6 0.54 10.4 0.4 2.3 2 0 0 2 2 2 0 Dynamin GTPase effector domain Ribosomal_L30 PF00327.20 KSA00291.1 - 3.5e-13 49.2 0.9 7e-13 48.2 0.9 1.5 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_L30_N PF08079.12 KSA00291.1 - 0.07 13.4 20.9 0.062 13.6 18.3 2.2 1 1 1 2 2 2 0 Ribosomal L30 N-terminal domain PNISR PF15996.5 KSA00291.1 - 0.22 11.8 11.1 0.32 11.3 11.1 1.2 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Dcc1 PF09724.9 KSA00292.1 - 1.4e-66 225.1 0.5 1.6e-66 224.9 0.5 1.0 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 DUF2487 PF10673.9 KSA00292.1 - 0.03 14.3 0.1 0.065 13.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2487) Mito_carr PF00153.27 KSA00293.1 - 9.2e-32 108.8 0.1 5.6e-17 61.5 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein Aminotran_5 PF00266.19 KSA00294.1 - 3.9e-97 325.5 0.0 4.6e-97 325.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KSA00294.1 - 2.4e-08 33.6 0.0 3.6e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Pyridoxal_deC PF00282.19 KSA00294.1 - 4.5e-05 22.4 0.0 7.3e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DegT_DnrJ_EryC1 PF01041.17 KSA00294.1 - 0.00016 21.2 0.0 0.00051 19.4 0.0 1.8 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Iso_dh PF00180.20 KSA00295.1 - 2.2e-126 421.7 0.0 2.5e-126 421.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF3507 PF12015.8 KSA00296.1 - 2.6e-55 187.0 0.3 7e-55 185.6 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3507) DUF2015 PF09435.10 KSA00297.1 - 1.4e-37 127.9 0.3 1.8e-37 127.6 0.3 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) RRM_1 PF00076.22 KSA00298.1 - 2.3e-41 139.5 0.3 3.5e-20 71.6 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KSA00298.1 - 1.3e-05 24.9 0.0 0.9 9.4 0.0 3.2 3 0 0 3 3 3 2 Occluded RNA-recognition motif Limkain-b1 PF11608.8 KSA00298.1 - 0.00059 19.8 0.1 13 5.9 0.0 3.6 3 1 0 3 3 3 2 Limkain b1 RRM_Rrp7 PF17799.1 KSA00298.1 - 0.0041 16.9 0.0 0.3 10.9 0.0 2.3 2 0 0 2 2 2 1 Rrp7 RRM-like N-terminal domain Nup35_RRM_2 PF14605.6 KSA00298.1 - 0.093 12.7 0.0 13 5.9 0.0 2.5 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif YflT PF11181.8 KSA00298.1 - 0.18 12.4 2.0 12 6.5 0.7 3.1 3 1 0 3 3 3 0 Heat induced stress protein YflT DUF1325 PF07039.11 KSA00299.1 - 4.1e-34 117.5 0.0 6.7e-34 116.8 0.0 1.3 1 0 0 1 1 1 1 SGF29 tudor-like domain Tudor_3 PF18115.1 KSA00299.1 - 0.00049 19.9 0.0 0.00088 19.1 0.0 1.4 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain Alpha-2-MRAP_C PF06401.11 KSA00299.1 - 0.0084 16.1 2.1 0.012 15.6 2.1 1.2 1 0 0 1 1 1 1 Alpha-2-macroglobulin RAP, C-terminal domain Frataxin_Cyay PF01491.16 KSA00299.1 - 0.024 14.7 0.4 0.05 13.7 0.4 1.5 1 0 0 1 1 1 0 Frataxin-like domain Spc7 PF08317.11 KSA00299.1 - 0.04 12.8 2.9 0.052 12.4 2.9 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Pex14_N PF04695.13 KSA00299.1 - 0.05 14.2 4.5 0.086 13.5 4.5 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TUDOR_5 PF18359.1 KSA00299.1 - 0.071 12.8 0.1 0.16 11.7 0.1 1.6 1 0 0 1 1 1 0 Histone methyltransferase Tudor domain 1 DUF4537 PF15057.6 KSA00299.1 - 0.095 12.7 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) DUF4471 PF14740.6 KSA00299.1 - 0.19 10.9 2.9 0.27 10.4 2.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4471) DUF1018 PF06252.12 KSA00299.1 - 1.5 9.9 3.6 18 6.4 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1018) PLDc_2 PF13091.6 KSA00300.1 - 2.4e-16 59.8 0.0 6.9e-07 29.2 0.0 2.7 3 1 0 3 3 3 2 PLD-like domain PLDc PF00614.22 KSA00300.1 - 1e-07 31.8 0.4 0.014 15.6 0.1 3.2 2 1 0 2 2 2 2 Phospholipase D Active site motif YchF-GTPase_C PF06071.13 KSA00301.1 - 1.4e-31 108.6 0.0 4.2e-31 107.0 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 KSA00301.1 - 8.6e-16 58.0 0.2 3.5e-15 56.1 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase TGS PF02824.21 KSA00301.1 - 1.3e-06 28.4 0.0 3e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 KSA00301.1 - 0.00071 19.1 0.1 0.0028 17.2 0.1 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B 2-Hacid_dh_C PF02826.19 KSA00301.1 - 0.0025 17.2 0.0 2.3 7.6 0.0 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TFIIE_alpha PF02002.17 KSA00301.1 - 0.5 10.3 3.2 0.28 11.0 0.5 2.0 2 0 0 2 2 2 0 TFIIE alpha subunit Ribosomal_L2_C PF03947.18 KSA00303.1 - 4.4e-50 169.1 3.8 1e-49 167.9 3.8 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 KSA00303.1 - 5.2e-26 90.4 0.6 2e-25 88.6 0.4 2.1 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain OSCP PF00213.18 KSA00304.1 - 1.7e-47 161.8 1.7 1.9e-47 161.6 1.7 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit DUF148 PF02520.17 KSA00304.1 - 0.055 13.6 1.2 0.92 9.6 0.2 2.2 1 1 1 2 2 2 0 Domain of unknown function DUF148 AhpC-TSA PF00578.21 KSA00306.1 - 5e-27 94.3 0.0 9e-27 93.5 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KSA00306.1 - 2.2e-19 69.6 0.0 3.2e-19 69.1 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 KSA00306.1 - 0.0045 17.1 0.0 0.0058 16.8 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme DUF2407 PF10302.9 KSA00307.1 - 0.22 12.1 1.6 5.1 7.7 0.2 3.1 2 1 0 2 2 2 0 DUF2407 ubiquitin-like domain RRM_1 PF00076.22 KSA00309.1 - 4.5e-11 42.4 0.0 7.3e-11 41.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KSA00309.1 - 0.00014 21.8 0.0 0.00022 21.1 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RCSD PF05177.12 KSA00309.1 - 0.035 15.0 6.0 0.059 14.3 6.0 1.4 1 0 0 1 1 1 0 RCSD region TIG PF01833.24 KSA00310.1 - 8.2e-09 35.4 1.0 3.2e-08 33.5 0.1 2.6 3 0 0 3 3 3 1 IPT/TIG domain Ank_2 PF12796.7 KSA00310.1 - 3.2e-08 34.1 0.0 8e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KSA00310.1 - 7.3e-08 32.5 0.1 0.00062 20.1 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 KSA00310.1 - 1.7e-06 28.2 0.0 7.3e-06 26.2 0.0 2.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 KSA00310.1 - 3e-06 27.7 0.4 0.00017 22.1 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KSA00310.1 - 8.5e-06 25.7 0.0 0.075 13.6 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat AMP-binding PF00501.28 KSA00311.1 - 2e-84 283.6 0.0 2.5e-84 283.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KSA00311.1 - 2.4e-25 89.3 0.0 1.9e-24 86.4 0.1 2.4 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 KSA00311.1 - 5.3e-17 61.5 0.5 1.2e-16 60.3 0.5 1.7 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus T4_deiodinase PF00837.17 KSA00311.1 - 0.12 11.7 0.0 0.24 10.6 0.0 1.4 1 0 0 1 1 1 0 Iodothyronine deiodinase OPA3 PF07047.12 KSA00312.1 - 4.1e-46 155.8 1.0 5.6e-46 155.4 1.0 1.1 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) DUF5320 PF17253.2 KSA00312.1 - 0.018 16.1 0.3 0.03 15.4 0.2 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF5320) bZIP_2 PF07716.15 KSA00312.1 - 0.021 14.9 0.5 0.021 14.9 0.5 2.0 2 0 0 2 2 2 0 Basic region leucine zipper THOC7 PF05615.13 KSA00312.1 - 0.041 14.2 1.2 0.057 13.7 1.2 1.5 1 1 0 1 1 1 0 Tho complex subunit 7 DivIC PF04977.15 KSA00312.1 - 0.061 13.1 0.7 0.13 12.0 0.2 1.8 2 0 0 2 2 2 0 Septum formation initiator Imm32 PF15566.6 KSA00312.1 - 0.072 12.9 0.6 10 6.0 0.0 2.4 2 0 0 2 2 2 0 Immunity protein 32 Histone PF00125.24 KSA00313.1 - 1.1e-16 61.4 0.0 1.4e-16 61.0 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 KSA00313.1 - 5.7e-13 48.4 1.2 9.6e-13 47.6 1.2 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 KSA00313.1 - 0.001 19.3 0.0 0.0016 18.6 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone NPR2 PF06218.11 KSA00314.1 - 1e-197 657.3 12.3 1e-197 657.3 12.3 1.4 2 0 0 2 2 2 1 Nitrogen permease regulator 2 MFS_1 PF07690.16 KSA00315.1 - 3.3e-37 128.2 33.5 3.3e-37 128.2 33.5 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KSA00315.1 - 4e-15 55.6 8.3 4e-15 55.6 8.3 2.8 3 1 0 3 3 3 1 Sugar (and other) transporter Cpn60_TCP1 PF00118.24 KSA00316.1 - 8.1e-84 282.0 11.0 2.4e-83 280.5 11.0 1.6 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Rrf2 PF02082.20 KSA00316.1 - 0.14 12.5 0.1 0.39 11.1 0.1 1.8 1 0 0 1 1 1 0 Transcriptional regulator RNA_pol_I_TF PF04090.12 KSA00317.1 - 2.2e-72 242.7 1.8 4.8e-72 241.6 1.8 1.6 1 0 0 1 1 1 1 RNA polymerase I specific initiation factor Clc-like PF07062.12 KSA00317.1 - 0.035 13.6 0.3 0.12 11.8 0.0 1.8 2 0 0 2 2 2 0 Clc-like DUF5078 PF16877.5 KSA00317.1 - 0.082 13.4 0.1 0.17 12.3 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5078) zf-rbx1 PF12678.7 KSA00318.1 - 4.6e-09 36.4 3.5 8.9e-09 35.5 3.5 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KSA00318.1 - 1.2e-07 32.0 6.1 3.1e-07 30.6 6.1 1.7 1 1 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 KSA00318.1 - 0.00028 20.7 2.1 0.00072 19.4 2.1 1.7 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KSA00318.1 - 0.00028 20.7 3.1 0.0027 17.5 0.9 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KSA00318.1 - 0.00063 19.3 0.4 0.0013 18.3 0.4 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 KSA00318.1 - 0.00071 19.4 2.5 0.00071 19.4 2.5 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KSA00318.1 - 0.0013 18.5 4.1 0.0029 17.4 4.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KSA00318.1 - 0.0017 18.3 3.0 0.0051 16.7 3.2 1.8 1 1 1 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KSA00318.1 - 0.0021 18.1 2.9 0.01 15.9 2.9 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 KSA00318.1 - 0.009 16.0 3.4 0.022 14.8 3.4 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zinc_ribbon_16 PF17034.5 KSA00318.1 - 0.015 15.5 0.6 0.03 14.5 0.3 1.6 1 1 0 1 1 1 0 Zinc-ribbon like family Rtf2 PF04641.12 KSA00318.1 - 0.053 12.9 0.3 0.095 12.0 0.3 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger zf-C3HC4_4 PF15227.6 KSA00318.1 - 0.056 13.6 0.6 0.15 12.3 0.6 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3H2C3 PF17122.5 KSA00318.1 - 0.1 12.6 0.6 0.27 11.3 0.6 1.7 1 0 0 1 1 1 0 Zinc-finger Cid2 PF09774.9 KSA00318.1 - 0.22 12.0 5.5 0.45 10.9 5.5 1.6 1 0 0 1 1 1 0 Caffeine-induced death protein 2 FANCL_C PF11793.8 KSA00318.1 - 0.23 11.6 2.6 0.85 9.8 2.6 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.6 KSA00318.1 - 0.37 10.6 2.3 0.82 9.5 0.8 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Afi1 PF07792.12 KSA00318.1 - 1.5 9.3 0.0 1.5 9.3 0.0 3.0 2 1 1 3 3 3 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Kinesin PF00225.23 KSA00319.1 - 3.9e-75 252.8 6.1 3.9e-75 252.8 6.1 2.7 2 1 0 2 2 2 1 Kinesin motor domain DUF3375 PF11855.8 KSA00319.1 - 0.055 12.4 0.0 0.12 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3375) Phasin PF05597.11 KSA00319.1 - 0.28 11.2 9.7 6.2 6.8 0.0 4.3 2 1 3 5 5 5 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Cob_adeno_trans PF01923.18 KSA00319.1 - 5.3 7.2 13.5 0.2 11.8 0.7 4.1 2 2 0 4 4 4 0 Cobalamin adenosyltransferase CENP-F_leu_zip PF10473.9 KSA00319.1 - 6.3 6.8 31.9 0.6 10.1 2.9 3.8 3 1 1 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 dsDNA_bind PF01984.20 KSA00320.1 - 2.6e-28 98.5 4.3 3.1e-28 98.2 4.3 1.1 1 0 0 1 1 1 1 Double-stranded DNA-binding domain Ras PF00071.22 KSA00321.1 - 5.2e-52 175.7 0.6 7.9e-52 175.1 0.6 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KSA00321.1 - 6.2e-34 116.8 0.1 1.2e-33 115.8 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KSA00321.1 - 1.1e-11 44.5 0.7 1.4e-11 44.2 0.7 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KSA00321.1 - 0.00076 19.1 0.4 0.0013 18.3 0.4 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Pox_L5 PF04872.13 KSA00321.1 - 0.0033 17.3 0.1 0.006 16.5 0.1 1.5 1 0 0 1 1 1 1 Poxvirus L5 protein family Gtr1_RagA PF04670.12 KSA00321.1 - 0.0056 16.1 0.7 0.0078 15.6 0.7 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MazE_antitoxin PF04014.18 KSA00321.1 - 0.012 15.5 0.4 0.085 12.8 0.3 2.1 2 0 0 2 2 2 0 Antidote-toxin recognition MazE, bacterial antitoxin zf-C2H2 PF00096.26 KSA00322.1 - 3.5e-10 39.8 15.8 5e-05 23.5 2.7 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KSA00322.1 - 1.5e-07 31.6 8.5 1.5e-07 31.6 8.5 2.8 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KSA00322.1 - 6.7e-06 26.5 13.5 0.00098 19.8 4.7 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KSA00322.1 - 0.002 18.1 2.5 0.002 18.1 2.5 2.2 2 0 0 2 2 2 1 C2H2-type zinc finger zf-Di19 PF05605.12 KSA00322.1 - 0.02 15.2 2.5 0.02 15.2 2.5 2.0 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding GAGA PF09237.11 KSA00322.1 - 0.031 14.1 0.9 0.063 13.1 0.9 1.5 1 0 0 1 1 1 0 GAGA factor Ogr_Delta PF04606.12 KSA00322.1 - 0.034 14.1 4.4 0.35 10.9 0.6 2.5 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger zf-C2H2_8 PF15909.5 KSA00322.1 - 0.055 13.8 4.3 0.11 12.8 3.6 1.8 2 0 0 2 2 2 0 C2H2-type zinc ribbon zf-LYAR PF08790.11 KSA00322.1 - 0.12 12.3 2.9 1.1 9.2 1.2 2.4 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-met PF12874.7 KSA00322.1 - 0.18 12.2 5.9 2.6 8.6 1.1 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KSA00322.1 - 0.35 11.2 6.0 0.11 12.9 1.1 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf_C2H2_ZHX PF18387.1 KSA00322.1 - 0.87 9.3 7.7 4.5 7.0 1.9 2.4 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2HE PF16278.5 KSA00322.1 - 1.2 9.7 5.4 0.46 11.0 2.3 2.0 2 0 0 2 2 1 0 C2HE / C2H2 / C2HC zinc-binding finger MFS_1 PF07690.16 KSA00323.1 - 2.2e-25 89.4 25.5 2.2e-25 89.4 25.5 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF658 PF04936.12 KSA00324.1 - 0.03 14.1 0.4 0.047 13.4 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF658) Metallophos PF00149.28 KSA00325.1 - 2.1e-35 123.1 0.3 5.7e-35 121.7 0.0 1.9 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KSA00325.1 - 2.5e-17 63.0 0.5 5.9e-17 61.8 0.5 1.7 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain CBM_48 PF02922.18 KSA00326.1 - 1.3e-15 57.5 0.5 2.3e-15 56.7 0.1 1.6 2 0 0 2 2 2 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Actin PF00022.19 KSA00327.1 - 1.4e-109 366.5 0.0 1.8e-109 366.1 0.0 1.1 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KSA00327.1 - 0.00028 19.8 0.0 0.092 11.5 0.0 2.7 2 1 0 2 2 2 2 MreB/Mbl protein Mitofilin PF09731.9 KSA00328.1 - 4.5e-52 177.7 24.3 4.4e-48 164.6 21.8 2.0 1 1 1 2 2 2 2 Mitochondrial inner membrane protein Tht1 PF04163.12 KSA00328.1 - 0.014 14.1 11.0 0.023 13.5 11.0 1.3 1 0 0 1 1 1 0 Tht1-like nuclear fusion protein PI3K_P85_iSH2 PF16454.5 KSA00328.1 - 0.02 14.5 17.7 0.022 14.4 11.2 2.7 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Glyco_hydr_30_2 PF14587.6 KSA00328.1 - 0.091 12.3 1.8 0.16 11.5 1.8 1.3 1 0 0 1 1 1 0 O-Glycosyl hydrolase family 30 ZnuA PF01297.17 KSA00328.1 - 0.22 10.9 2.0 0.4 10.1 2.0 1.4 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic Phasin PF05597.11 KSA00328.1 - 0.37 10.8 5.7 0.16 12.0 0.4 2.8 3 1 0 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) MRP-S27 PF10037.9 KSA00328.1 - 1.8 7.3 15.0 0.02 13.8 5.3 2.0 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S27 WD40 PF00400.32 KSA00329.1 - 9.6e-30 102.2 25.3 2.1e-05 25.2 0.2 10.7 10 1 1 11 11 11 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KSA00329.1 - 8.3e-17 61.3 0.6 0.00097 19.4 0.0 7.3 5 2 3 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KSA00329.1 - 0.00033 20.5 3.2 0.22 11.5 0.0 4.9 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat Lactonase PF10282.9 KSA00329.1 - 0.00082 18.7 0.6 0.012 14.9 0.1 2.8 3 0 0 3 3 3 1 Lactonase, 7-bladed beta-propeller Rav1p_C PF12234.8 KSA00329.1 - 0.0025 16.3 0.0 0.0068 14.9 0.0 1.7 1 0 0 1 1 1 1 RAVE protein 1 C terminal UTP15_C PF09384.10 KSA00330.1 - 1.3e-44 151.5 0.1 1.9e-44 150.9 0.1 1.3 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 KSA00330.1 - 1.8e-10 41.2 2.5 0.55 11.2 0.0 6.2 6 1 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KSA00330.1 - 2e-07 31.2 0.0 0.21 11.9 0.0 4.7 1 1 4 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 KSA00330.1 - 0.0015 18.5 0.0 2.6 8.1 0.0 3.8 2 1 1 3 3 3 1 Ciliary BBSome complex subunit 2, middle region Arc_PepC PF06819.11 KSA00330.1 - 0.047 13.8 0.1 1.4 9.1 0.1 2.4 2 0 0 2 2 2 0 Archaeal Peptidase A24 C-terminal Domain PHD PF00628.29 KSA00331.1 - 0.0017 18.2 6.7 0.0038 17.1 6.7 1.6 1 0 0 1 1 1 1 PHD-finger RAG2_PHD PF13341.6 KSA00331.1 - 0.0086 16.1 0.3 0.019 15.0 0.3 1.6 1 0 0 1 1 1 1 RAG2 PHD domain zf-HC5HC2H PF13771.6 KSA00331.1 - 0.025 14.8 1.4 0.059 13.6 1.4 1.7 1 0 0 1 1 1 0 PHD-like zinc-binding domain Ribosomal_L3 PF00297.22 KSA00332.1 - 1.2e-184 613.4 11.6 1.4e-184 613.3 11.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 AT_hook PF02178.19 KSA00333.1 - 0.021 14.6 2.2 0.021 14.6 2.2 2.1 2 0 0 2 2 2 0 AT hook motif ATP-synt_S1 PF05827.12 KSA00334.1 - 8.2e-05 22.5 0.9 0.00015 21.6 0.9 1.3 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) AAA_17 PF13207.6 KSA00334.1 - 0.0052 17.2 0.1 0.008 16.6 0.1 1.3 1 0 0 1 1 1 1 AAA domain VMA21 PF09446.10 KSA00335.1 - 1.9e-10 40.7 15.5 4.3e-10 39.6 15.5 1.5 1 1 0 1 1 1 1 VMA21-like domain Med18 PF09637.10 KSA00336.1 - 2.1e-108 361.9 3.4 2.6e-108 361.6 3.4 1.1 1 0 0 1 1 1 1 Med18 protein DUF615 PF04751.14 KSA00337.1 - 0.085 12.8 0.4 0.12 12.4 0.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF615) Pescadillo_N PF06732.11 KSA00338.1 - 1.3e-123 411.9 0.9 1.3e-123 411.9 0.9 1.8 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT_2 PF16589.5 KSA00338.1 - 3e-08 34.0 0.0 7.5e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KSA00338.1 - 0.0078 16.6 0.0 0.03 14.7 0.0 2.1 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 KSA00338.1 - 0.031 14.6 0.1 0.15 12.4 0.0 2.2 2 0 0 2 2 2 0 DNA ligase 3 BRCT domain Baculo_LEF-10 PF07206.11 KSA00339.1 - 0.89 9.8 4.9 15 5.9 1.6 2.8 2 1 1 3 3 3 0 Baculovirus late expression factor 10 (LEF-10) Acyltransferase PF01553.21 KSA00341.1 - 1.4e-10 40.9 0.0 7.6e-10 38.5 0.0 2.0 1 1 0 1 1 1 1 Acyltransferase PPR_2 PF13041.6 KSA00342.1 - 0.00015 21.9 6.0 1.1 9.6 0.0 5.2 6 0 0 6 6 6 2 PPR repeat family PPR PF01535.20 KSA00342.1 - 0.0022 18.1 0.1 8.1 6.9 0.0 4.2 3 0 0 3 3 3 2 PPR repeat PPR_long PF17177.4 KSA00342.1 - 0.0048 16.3 0.4 0.13 11.6 0.0 3.2 2 1 0 3 3 3 1 Pentacotripeptide-repeat region of PRORP Exog_C PF18026.1 KSA00342.1 - 0.015 15.3 0.5 0.66 10.1 0.5 3.0 2 0 0 2 2 2 0 Endo/exonuclease (EXOG) C-terminal domain BET PF17035.5 KSA00342.1 - 9.3 6.5 8.9 2.7 8.2 0.4 3.9 3 0 0 3 3 3 0 Bromodomain extra-terminal - transcription regulation Kinesin PF00225.23 KSA00343.1 - 1.3e-99 333.4 6.2 1.3e-99 333.4 6.2 2.1 2 1 1 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 KSA00343.1 - 9.6e-48 161.9 0.1 9.6e-48 161.9 0.1 2.6 2 1 0 3 3 3 1 Microtubule binding ADIP PF11559.8 KSA00343.1 - 0.002 18.2 8.3 0.002 18.2 8.3 5.4 2 1 4 6 6 6 2 Afadin- and alpha -actinin-Binding Csm1_N PF18504.1 KSA00343.1 - 0.54 10.6 39.4 0.82 10.1 1.0 6.2 2 2 3 5 5 5 0 Csm1 N-terminal domain Spc7 PF08317.11 KSA00343.1 - 2.2 7.1 43.8 0.55 9.0 13.5 2.9 1 1 2 3 3 3 0 Spc7 kinetochore protein DUF4407 PF14362.6 KSA00343.1 - 5.7 6.2 23.2 2.4e+03 -2.4 23.2 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Ribosomal_L29 PF00831.23 KSA00343.1 - 7.9 6.5 18.5 3.9 7.5 2.2 4.4 3 1 0 3 3 3 0 Ribosomal L29 protein Rrp15p PF07890.12 KSA00344.1 - 3e-31 108.5 11.6 3e-31 108.5 11.6 2.3 2 1 0 2 2 2 1 Rrp15p CDC45 PF02724.14 KSA00344.1 - 0.17 10.1 16.6 0.18 10.1 16.6 1.2 1 0 0 1 1 1 0 CDC45-like protein MFS_1 PF07690.16 KSA00345.1 - 1.1e-22 80.5 28.2 8.2e-16 57.9 8.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily SGS PF05002.15 KSA00346.1 - 4e-27 94.2 9.0 1.2e-26 92.6 9.0 1.9 1 1 0 1 1 1 1 SGS domain CS PF04969.16 KSA00346.1 - 1e-16 61.7 1.8 1.5e-16 61.1 0.8 1.8 2 0 0 2 2 2 1 CS domain TPR_2 PF07719.17 KSA00346.1 - 4.7e-11 41.9 5.6 6.9e-05 22.7 0.3 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 KSA00346.1 - 9.8e-10 38.6 1.2 1.4e-08 34.9 0.1 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 KSA00346.1 - 7.8e-09 35.0 6.1 0.0019 17.9 0.6 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 KSA00346.1 - 3.7e-07 29.9 7.3 0.0051 16.9 0.5 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 KSA00346.1 - 1.3e-05 25.6 1.9 2 9.3 0.1 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KSA00346.1 - 0.00012 22.5 0.2 0.0027 18.2 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KSA00346.1 - 0.00025 21.6 0.5 0.43 11.3 0.1 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 KSA00346.1 - 0.001 18.7 1.5 0.61 9.8 0.2 2.7 2 0 0 2 2 2 2 TPR repeat TPR_9 PF13371.6 KSA00346.1 - 0.0033 17.5 0.0 0.042 14.0 0.0 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 KSA00346.1 - 0.048 14.1 1.8 0.24 11.9 0.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 KSA00346.1 - 0.12 12.4 0.5 13 6.1 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KSA00346.1 - 0.65 10.3 5.5 10 6.4 0.3 2.5 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 HAGH_C PF16123.5 KSA00347.1 - 4.5e-21 75.1 0.9 7.4e-21 74.5 0.9 1.4 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 KSA00347.1 - 3.4e-13 50.1 1.2 1.9e-12 47.6 1.2 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KSA00347.1 - 0.0024 17.4 1.2 0.012 15.1 1.0 2.2 1 1 1 2 2 2 1 Beta-lactamase superfamily domain Y_phosphatase2 PF03162.13 KSA00348.1 - 6.1e-41 139.8 0.2 2.9e-38 131.0 0.2 2.1 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 KSA00348.1 - 6.5e-08 32.8 0.0 9.4e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family GLEYA PF10528.9 KSA00350.1 - 1.1e-23 83.4 1.3 1.1e-23 83.4 1.3 2.1 2 0 0 2 2 2 1 GLEYA domain PA14 PF07691.12 KSA00350.1 - 6.6e-14 51.9 0.0 1.2e-13 51.2 0.0 1.5 1 0 0 1 1 1 1 PA14 domain Dak1 PF02733.17 KSA00352.1 - 7.6e-90 300.9 0.0 1.2e-89 300.4 0.0 1.3 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 KSA00352.1 - 6.7e-41 140.1 0.1 1.1e-40 139.4 0.1 1.3 1 0 0 1 1 1 1 DAK2 domain LacAB_rpiB PF02502.18 KSA00353.1 - 4.8e-43 146.5 0.1 5.5e-43 146.3 0.1 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase Gly_rich_SFCGS PF14272.6 KSA00353.1 - 0.00037 20.5 0.1 0.00069 19.6 0.0 1.5 2 0 0 2 2 2 1 Glycine-rich SFCGS ADH_N PF08240.12 KSA00354.1 - 7.1e-31 106.3 2.0 1.2e-30 105.6 2.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KSA00354.1 - 1.4e-13 51.0 0.0 2.4e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KSA00354.1 - 4e-06 26.5 0.0 1.5e-05 24.6 0.0 2.0 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KSA00354.1 - 0.052 14.6 0.0 0.12 13.4 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Sugar_tr PF00083.24 KSA00355.1 - 2.7e-107 359.4 15.8 3.2e-107 359.2 15.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KSA00355.1 - 6.3e-21 74.7 19.4 2.5e-15 56.3 1.3 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Aldo_ket_red PF00248.21 KSA00356.1 - 1.6e-42 145.7 0.1 1.2e-40 139.6 0.1 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family GntR PF00392.21 KSA00356.1 - 0.0036 16.9 0.0 0.013 15.2 0.0 1.9 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family ACR_tran PF00873.19 KSA00356.1 - 0.19 9.3 0.0 0.23 9.1 0.0 1.0 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family Maf1 PF09174.10 KSA00357.1 - 6.1e-33 114.4 13.0 7.5e-25 88.1 1.4 3.2 2 1 0 2 2 2 2 Maf1 regulator RNA_pol_3_Rpc31 PF11705.8 KSA00357.1 - 1.2 9.3 13.1 2.8 8.2 13.1 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 HCMVantigenic_N PF12154.8 KSA00357.1 - 5.5 7.2 10.2 1 9.5 2.7 2.8 3 0 0 3 3 3 0 Glycoprotein B N-terminal antigenic domain of HCMV Rad51 PF08423.11 KSA00358.1 - 2.1e-32 112.4 1.2 2.3e-29 102.4 1.6 2.8 2 1 0 2 2 2 2 Rad51 ATPase PF06745.13 KSA00358.1 - 3.5e-11 42.9 0.6 5.6e-10 39.0 0.1 2.7 3 0 0 3 3 3 1 KaiC AAA_25 PF13481.6 KSA00358.1 - 1e-08 35.0 0.0 3e-08 33.5 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 KSA00358.1 - 0.00056 20.0 0.2 0.012 15.7 0.2 2.8 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KSA00358.1 - 0.00059 19.6 0.0 0.0014 18.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 KSA00358.1 - 0.0019 17.7 0.0 0.0038 16.7 0.0 1.4 1 0 0 1 1 1 1 recA bacterial DNA recombination protein ABC_tran PF00005.27 KSA00358.1 - 0.002 18.7 3.3 0.002 18.7 0.7 2.3 2 1 0 2 2 2 1 ABC transporter Pyr_redox_2 PF07992.14 KSA00359.1 - 3.1e-36 125.1 0.4 3.7e-36 124.9 0.4 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KSA00359.1 - 3.6e-11 43.5 0.5 4e-07 30.5 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KSA00359.1 - 2.3e-07 30.4 0.5 0.00014 21.3 0.1 2.4 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KSA00359.1 - 0.0015 18.5 1.6 3.7 7.5 0.0 3.7 3 1 1 4 4 4 2 FAD-NAD(P)-binding DAO PF01266.24 KSA00359.1 - 0.0038 16.9 2.9 2 7.9 0.0 3.7 4 0 0 4 4 4 1 FAD dependent oxidoreductase GT-D PF08759.11 KSA00359.1 - 0.037 13.7 0.1 2.9 7.5 0.0 2.3 2 0 0 2 2 2 0 Glycosyltransferase GT-D fold Trp_halogenase PF04820.14 KSA00359.1 - 0.045 12.6 7.2 0.49 9.2 0.1 3.5 3 1 1 4 4 4 0 Tryptophan halogenase Pyr_redox_2 PF07992.14 KSA00360.1 - 2.7e-34 118.8 0.1 3.2e-34 118.5 0.1 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KSA00360.1 - 1.7e-09 38.1 0.2 7.1e-05 23.3 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KSA00360.1 - 2.9e-07 30.0 0.0 8.8e-06 25.2 0.0 2.1 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KSA00360.1 - 0.0048 16.9 0.1 13 5.8 0.0 3.9 4 0 0 4 4 4 1 FAD-NAD(P)-binding Trp_halogenase PF04820.14 KSA00360.1 - 0.016 14.1 4.2 0.18 10.6 0.1 3.0 3 1 0 3 3 3 0 Tryptophan halogenase DAO PF01266.24 KSA00360.1 - 0.05 13.2 2.7 12 5.4 0.0 3.6 3 1 1 4 4 4 0 FAD dependent oxidoreductase HI0933_like PF03486.14 KSA00360.1 - 0.076 11.7 0.6 6.9 5.3 0.0 3.0 4 0 0 4 4 4 0 HI0933-like protein Pyrophosphatase PF00719.19 KSA00361.1 - 8.7e-60 201.2 0.2 1.2e-59 200.7 0.2 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase TP6A_N PF04406.14 KSA00362.1 - 8.8e-13 48.0 0.1 1.5e-12 47.3 0.1 1.4 1 0 0 1 1 1 1 Type IIB DNA topoisomerase RCR PF12273.8 KSA00363.1 - 8e-39 133.0 3.9 1.1e-38 132.5 3.9 1.2 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red DUF2167 PF09935.9 KSA00363.1 - 0.057 12.6 0.0 0.091 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2167) Ac110_PIF PF07280.11 KSA00363.1 - 0.16 11.8 1.0 0.31 10.9 1.0 1.5 1 0 0 1 1 1 0 Per os infectivity factor AC110 RSN1_7TM PF02714.15 KSA00364.1 - 2.6e-82 276.2 20.5 2.6e-82 276.2 20.5 2.4 3 0 0 3 3 3 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KSA00364.1 - 9.1e-42 142.5 0.9 9.1e-42 142.5 0.9 2.4 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KSA00364.1 - 2.8e-29 102.6 0.6 7.5e-29 101.2 0.6 1.8 1 1 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 KSA00364.1 - 5.9e-23 80.9 0.2 1.9e-22 79.2 0.1 1.9 2 0 0 2 2 2 1 Extracellular tail, of 10TM putative phosphate transporter RSN1_7TM PF02714.15 KSA00365.1 - 3e-80 269.5 22.8 4.1e-80 269.0 20.5 2.1 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KSA00365.1 - 6.3e-42 143.0 1.7 6.3e-42 143.0 1.7 2.4 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KSA00365.1 - 6.7e-28 98.1 1.1 1.6e-27 96.8 1.1 1.7 1 1 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 KSA00365.1 - 1e-20 73.7 0.2 3.1e-20 72.1 0.1 1.9 2 0 0 2 2 2 1 Extracellular tail, of 10TM putative phosphate transporter YajC PF02699.15 KSA00365.1 - 0.52 10.2 0.0 0.52 10.2 0.0 2.3 3 0 0 3 3 3 0 Preprotein translocase subunit Sugar_tr PF00083.24 KSA00367.1 - 2.4e-53 181.6 28.2 1.5e-52 179.0 28.2 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KSA00367.1 - 3.3e-18 65.8 58.3 8.7e-14 51.2 38.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DMT_YdcZ PF04657.13 KSA00367.1 - 0.016 15.4 2.0 0.016 15.4 2.0 3.8 3 1 0 3 3 3 0 Putative inner membrane exporter, YdcZ HMGL-like PF00682.19 KSA00368.1 - 3.8e-83 279.1 0.0 1e-82 277.6 0.0 1.7 2 0 0 2 2 2 1 HMGL-like LeuA_dimer PF08502.10 KSA00368.1 - 1.5e-27 96.1 0.1 2.5e-27 95.4 0.1 1.4 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain CLZ PF16526.5 KSA00369.1 - 0.017 15.5 1.0 0.022 15.1 1.0 1.2 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF3450 PF11932.8 KSA00369.1 - 0.025 13.9 0.7 0.027 13.8 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF2951 PF11166.8 KSA00369.1 - 0.43 10.8 3.1 0.48 10.7 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) Syja_N PF02383.18 KSA00370.1 - 6e-56 190.1 0.3 1.5e-55 188.8 0.3 1.6 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.23 KSA00370.1 - 4.1e-09 36.3 0.0 7.2e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Trm112p PF03966.16 KSA00373.1 - 9.7e-22 77.3 0.0 1.6e-21 76.6 0.0 1.4 1 1 0 1 1 1 1 Trm112p-like protein Pkinase PF00069.25 KSA00374.1 - 5.3e-76 255.5 0.3 8.3e-76 254.8 0.3 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KSA00374.1 - 2.5e-31 108.9 0.1 2.2e-22 79.6 0.2 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KSA00374.1 - 1e-07 31.6 0.9 0.06 12.6 0.0 3.2 2 1 0 3 3 3 3 Kinase-like Haspin_kinase PF12330.8 KSA00374.1 - 0.00036 19.6 0.5 0.0019 17.2 0.1 2.0 1 1 1 2 2 2 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KSA00374.1 - 0.0017 17.2 0.0 0.0048 15.7 0.0 1.7 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KSA00374.1 - 0.031 13.6 0.0 0.054 12.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KSA00374.1 - 0.2 11.5 0.0 8.1 6.3 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 KSA00375.1 - 9.8e-68 228.4 0.0 3.6e-67 226.5 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KSA00375.1 - 4.8e-49 167.0 0.0 9.5e-49 166.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KSA00375.1 - 2.8e-06 26.4 0.0 5.4e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KSA00375.1 - 0.002 17.5 0.0 0.0043 16.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like VF530 PF09905.9 KSA00375.1 - 0.43 10.8 3.9 0.54 10.5 0.2 3.0 4 0 0 4 4 4 0 DNA-binding protein VF530 EF-hand_2 PF09068.11 KSA00375.1 - 5.8 7.1 7.1 44 4.2 0.1 3.2 3 0 0 3 3 3 0 EF hand Pex2_Pex12 PF04757.14 KSA00376.1 - 1.1e-31 110.2 7.5 1.6e-31 109.6 7.5 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_5 PF14634.6 KSA00376.1 - 0.0016 18.4 7.8 0.0039 17.1 7.8 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KSA00376.1 - 0.0016 18.2 0.6 0.0016 18.2 0.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KSA00376.1 - 0.0027 17.7 5.5 0.0058 16.6 5.5 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KSA00376.1 - 0.0096 16.1 4.0 0.029 14.5 4.0 1.9 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 KSA00376.1 - 0.039 14.2 4.7 0.079 13.3 4.7 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain PPP4R2 PF09184.11 KSA00376.1 - 0.2 11.2 12.6 0.34 10.4 12.6 1.3 1 0 0 1 1 1 0 PPP4R2 zf-C3HC4 PF00097.25 KSA00376.1 - 0.23 11.4 9.9 0.52 10.2 9.9 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KSA00376.1 - 1.6 9.1 7.9 9.3 6.7 7.9 2.2 1 1 0 1 1 1 0 Ring finger domain CPL PF08144.11 KSA00377.1 - 9e-42 142.8 0.3 9e-42 142.8 0.3 5.2 5 1 1 6 6 6 1 CPL (NUC119) domain PUF PF00806.19 KSA00377.1 - 2.1e-06 27.1 3.0 0.65 9.8 0.0 5.5 6 0 0 6 6 6 2 Pumilio-family RNA binding repeat DUF4253 PF14062.6 KSA00377.1 - 0.0044 17.2 0.0 0.28 11.4 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4253) SAC3 PF12209.8 KSA00377.1 - 0.22 11.8 3.6 5.1 7.4 0.1 4.1 3 1 0 3 3 3 0 Leucine permease transcriptional regulator helical domain CDC45 PF02724.14 KSA00377.1 - 1.3 7.2 16.9 2.2 6.5 16.9 1.4 1 0 0 1 1 1 0 CDC45-like protein Thioredoxin PF00085.20 KSA00378.1 - 2.5e-27 94.9 0.1 3e-27 94.6 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KSA00378.1 - 2.7e-05 24.6 0.1 0.00017 22.0 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 KSA00378.1 - 0.00024 20.9 0.0 0.00029 20.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.16 KSA00378.1 - 0.0044 16.0 0.0 0.0056 15.6 0.0 1.1 1 0 0 1 1 1 1 Phosducin Thioredoxin_8 PF13905.6 KSA00378.1 - 0.0048 17.2 0.0 0.011 16.1 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 KSA00378.1 - 0.0062 15.9 0.0 0.0073 15.7 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Redoxin PF08534.10 KSA00378.1 - 0.056 13.2 0.1 0.095 12.4 0.0 1.4 1 1 0 1 1 1 0 Redoxin TraF PF13728.6 KSA00378.1 - 0.071 12.9 0.0 0.085 12.7 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_7 PF13899.6 KSA00378.1 - 0.096 12.9 0.1 0.14 12.4 0.1 1.4 1 1 0 1 1 1 0 Thioredoxin-like DUF5130 PF17174.4 KSA00378.1 - 0.11 12.7 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5130) AAA PF00004.29 KSA00379.1 - 4.1e-40 137.3 0.0 6.8e-40 136.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KSA00379.1 - 2.4e-10 40.1 0.7 4.7e-10 39.1 0.7 1.5 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 KSA00379.1 - 7.7e-10 38.6 0.1 1.6e-09 37.6 0.1 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 KSA00379.1 - 1e-05 25.7 0.2 4e-05 23.8 0.0 2.0 2 1 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KSA00379.1 - 1.2e-05 25.6 0.2 0.017 15.4 0.1 2.5 1 1 1 2 2 2 2 AAA domain DUF815 PF05673.13 KSA00379.1 - 5.5e-05 22.4 0.0 9.6e-05 21.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 KSA00379.1 - 0.00035 20.6 0.1 0.0022 18.0 0.1 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KSA00379.1 - 0.00054 20.4 0.1 0.0043 17.4 0.1 2.1 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KSA00379.1 - 0.00093 19.0 0.0 0.0019 18.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 KSA00379.1 - 0.0023 18.2 0.3 0.0083 16.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KSA00379.1 - 0.011 16.3 0.0 0.032 14.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_3 PF07726.11 KSA00379.1 - 0.012 15.4 0.0 0.027 14.3 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KSA00379.1 - 0.015 15.5 0.0 0.032 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KSA00379.1 - 0.018 14.7 0.0 0.037 13.8 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.13 KSA00379.1 - 0.022 13.9 0.2 0.065 12.4 0.1 1.7 1 1 0 1 1 1 0 TIP49 P-loop domain AAA_14 PF13173.6 KSA00379.1 - 0.023 14.7 0.1 0.087 12.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 KSA00379.1 - 0.039 13.3 0.1 0.47 9.8 0.1 2.2 1 1 1 2 2 2 0 KaiC RNA_helicase PF00910.22 KSA00379.1 - 0.051 14.0 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.21 KSA00379.1 - 0.056 12.8 0.1 0.11 11.8 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 KSA00379.1 - 0.096 11.9 0.1 0.18 11.1 0.1 1.3 1 0 0 1 1 1 0 Zeta toxin NTPase_1 PF03266.15 KSA00379.1 - 0.1 12.5 0.1 0.84 9.5 0.0 2.4 2 0 0 2 2 2 0 NTPase AAA_25 PF13481.6 KSA00379.1 - 0.11 12.0 0.3 0.37 10.3 0.0 2.0 3 0 0 3 3 3 0 AAA domain PhoH PF02562.16 KSA00379.1 - 0.12 11.8 0.2 0.46 9.9 0.1 1.9 2 0 0 2 2 2 0 PhoH-like protein AAA_24 PF13479.6 KSA00379.1 - 0.16 11.7 1.9 0.37 10.5 0.1 2.3 3 0 0 3 3 3 0 AAA domain NACHT PF05729.12 KSA00379.1 - 0.18 11.7 0.3 0.61 10.0 0.1 1.9 2 0 0 2 2 2 0 NACHT domain Bax1-I PF01027.20 KSA00380.1 - 7.9e-51 172.8 27.1 9e-51 172.6 27.1 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 BaxI_1 PF12811.7 KSA00380.1 - 0.0011 18.6 17.7 0.0016 18.0 17.7 1.3 1 1 0 1 1 1 1 Bax inhibitor 1 like FUSC PF04632.12 KSA00380.1 - 0.15 10.5 10.0 0.016 13.8 3.0 2.0 1 1 1 2 2 2 0 Fusaric acid resistance protein family zf-RING_UBOX PF13445.6 KSA00381.1 - 4.9e-11 42.5 2.1 1.2e-10 41.3 1.0 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 KSA00381.1 - 4e-10 39.9 4.3 6.1e-10 39.3 4.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KSA00381.1 - 4.6e-10 39.2 2.7 4.6e-10 39.2 2.7 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KSA00381.1 - 6.5e-10 38.7 4.9 1.1e-09 37.9 4.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KSA00381.1 - 6e-08 32.7 4.7 2e-07 31.1 4.8 1.9 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 KSA00381.1 - 8e-08 32.0 8.0 2.9e-07 30.3 8.0 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KSA00381.1 - 1.5e-07 31.3 6.9 3.2e-07 30.2 6.9 1.6 1 1 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KSA00381.1 - 9.2e-07 28.6 9.2 2.4e-05 24.1 9.0 2.7 1 1 1 2 2 2 2 Prokaryotic RING finger family 4 zf-Di19 PF05605.12 KSA00381.1 - 0.0013 19.0 1.7 0.57 10.5 1.0 2.3 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding TerY_C PF15616.6 KSA00381.1 - 0.0015 18.6 4.7 0.025 14.7 2.5 2.1 1 1 2 3 3 3 1 TerY-C metal binding domain zf-Nse PF11789.8 KSA00381.1 - 0.003 17.3 0.9 0.0054 16.5 0.6 1.6 1 1 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_11 PF17123.5 KSA00381.1 - 0.0036 17.0 5.7 0.0083 15.9 5.7 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-ANAPC11 PF12861.7 KSA00381.1 - 0.0038 17.2 3.4 0.026 14.6 3.4 2.2 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KSA00381.1 - 0.0094 16.2 8.5 0.059 13.7 8.5 2.2 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_4 PF14570.6 KSA00381.1 - 0.019 14.7 5.6 0.12 12.1 5.7 2.2 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 KSA00381.1 - 0.021 15.0 4.9 0.063 13.5 4.9 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain zf-UDP PF14569.6 KSA00381.1 - 0.022 14.9 3.3 0.038 14.1 3.3 1.4 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-RING_14 PF17978.1 KSA00381.1 - 0.027 14.9 1.5 0.044 14.2 1.5 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Mistic PF11458.8 KSA00381.1 - 0.034 14.1 0.8 0.057 13.4 0.8 1.3 1 0 0 1 1 1 0 Membrane-integrating protein Mistic DUF4451 PF14616.6 KSA00381.1 - 0.042 14.0 4.3 0.13 12.4 0.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4451) FYVE PF01363.21 KSA00381.1 - 0.043 14.0 6.2 0.11 12.7 6.2 1.7 1 1 0 1 1 1 0 FYVE zinc finger YacG PF03884.14 KSA00381.1 - 0.11 12.3 4.2 4.3 7.1 0.0 2.4 2 0 0 2 2 2 0 DNA gyrase inhibitor YacG zf-RING_10 PF16685.5 KSA00381.1 - 0.21 11.8 6.3 3.5 7.9 5.1 2.5 1 1 1 2 2 2 0 zinc RING finger of MSL2 DUF1644 PF07800.12 KSA00381.1 - 0.23 11.5 3.9 3.4 7.7 0.3 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1644) zf-RING_6 PF14835.6 KSA00381.1 - 3.4 7.6 6.4 1 9.3 3.2 1.8 2 1 0 2 2 1 0 zf-RING of BARD1-type protein PH PF00169.29 KSA00382.1 - 2.2e-10 41.0 0.5 5.6e-10 39.7 0.2 1.9 2 0 0 2 2 2 1 PH domain Phe_tRNA-synt_N PF02912.18 KSA00382.1 - 0.0048 16.8 0.7 0.012 15.5 0.7 1.6 1 0 0 1 1 1 1 Aminoacyl tRNA synthetase class II, N-terminal domain Fzo_mitofusin PF04799.13 KSA00382.1 - 0.33 10.5 1.8 1 8.9 1.8 1.8 1 0 0 1 1 1 0 fzo-like conserved region Ribosomal_L14 PF00238.19 KSA00383.1 - 2.3e-33 114.9 0.0 2.7e-33 114.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e WSC PF01822.19 KSA00384.1 - 3.8e-10 39.8 11.1 3.8e-10 39.8 11.1 3.2 2 1 0 2 2 2 1 WSC domain Utp14 PF04615.13 KSA00384.1 - 0.002 16.8 13.3 0.0026 16.4 13.3 1.1 1 0 0 1 1 1 1 Utp14 protein DUF2613 PF11021.8 KSA00384.1 - 0.081 13.0 1.0 1.6 8.9 0.0 3.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) DUF2207 PF09972.9 KSA00384.1 - 0.083 11.6 0.0 0.15 10.8 0.0 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Cytomega_TRL10 PF06084.11 KSA00384.1 - 0.12 12.4 0.1 0.12 12.4 0.1 2.4 3 0 0 3 3 3 0 Cytomegalovirus TRL10 protein Adeno_E3_CR2 PF02439.15 KSA00384.1 - 0.14 11.9 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 PPP4R2 PF09184.11 KSA00384.1 - 0.7 9.4 30.7 0.012 15.2 12.5 2.2 1 1 1 2 2 2 0 PPP4R2 Use1 PF09753.9 KSA00385.1 - 1.3e-16 61.1 1.0 1.7e-16 60.7 1.0 1.2 1 0 0 1 1 1 1 Membrane fusion protein Use1 RRM_1 PF00076.22 KSA00386.1 - 1.8e-23 82.1 1.6 4.9e-07 29.5 0.5 4.7 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KSA00386.1 - 2.4e-08 33.7 0.2 0.22 11.4 0.0 4.3 4 0 0 4 4 4 3 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 KSA00386.1 - 0.063 13.3 0.1 3.3 7.8 0.2 3.0 2 1 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_Rrp7 PF17799.1 KSA00386.1 - 0.099 12.4 0.0 1.5 8.6 0.0 2.7 3 0 0 3 3 3 0 Rrp7 RRM-like N-terminal domain PI3_PI4_kinase PF00454.27 KSA00388.1 - 2.4e-53 181.5 2.0 5.4e-53 180.4 0.0 2.8 3 0 0 3 3 3 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.8 KSA00388.1 - 1.7e-32 112.7 5.3 2.3e-32 112.2 0.9 3.5 3 0 0 3 3 3 1 Telomere-length maintenance and DNA damage repair FATC PF02260.20 KSA00388.1 - 3.4e-13 49.1 0.0 9.3e-13 47.8 0.0 1.8 1 0 0 1 1 1 1 FATC domain MSA-2c PF12238.8 KSA00388.1 - 0.51 10.3 6.5 7.5 6.5 0.2 4.1 3 0 0 3 3 3 0 Merozoite surface antigen 2c GCV_T PF01571.21 KSA00389.1 - 6.7e-82 274.7 0.0 8.1e-82 274.4 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 KSA00389.1 - 3.9e-16 58.7 0.0 9.3e-16 57.5 0.0 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain SoxG PF04268.12 KSA00389.1 - 0.00011 22.3 0.0 0.0042 17.2 0.0 2.5 2 1 0 3 3 3 1 Sarcosine oxidase, gamma subunit family S-layer PF07752.11 KSA00389.1 - 0.034 13.2 0.1 0.058 12.4 0.1 1.3 1 0 0 1 1 1 0 S-layer protein Hexapep PF00132.24 KSA00389.1 - 0.047 13.4 0.2 1.5 8.6 0.1 2.6 2 0 0 2 2 2 0 Bacterial transferase hexapeptide (six repeats) SRP_TPR_like PF17004.5 KSA00391.1 - 2.5e-11 43.6 7.5 5.9e-09 36.0 2.7 2.9 2 0 0 2 2 2 2 Putative TPR-like repeat TPR_2 PF07719.17 KSA00391.1 - 2.1e-05 24.3 6.1 0.042 14.0 0.5 5.3 6 0 0 6 6 5 1 Tetratricopeptide repeat SRP72 PF08492.12 KSA00391.1 - 0.00028 21.3 4.8 0.00028 21.3 4.8 2.6 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_12 PF13424.6 KSA00391.1 - 0.00069 19.9 2.5 1.6 9.1 0.1 4.2 3 1 0 3 3 3 1 Tetratricopeptide repeat DUF627 PF04781.12 KSA00391.1 - 0.001 19.0 0.4 0.027 14.5 0.0 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF627) TPR_14 PF13428.6 KSA00391.1 - 0.0014 19.2 0.2 35 5.6 0.0 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KSA00391.1 - 0.0064 16.7 10.4 5.1 7.4 1.3 4.8 2 2 3 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 KSA00391.1 - 0.012 15.5 0.7 5.3 7.1 0.2 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Vps39_1 PF10366.9 KSA00391.1 - 0.018 15.3 0.7 0.018 15.3 0.7 4.9 4 2 2 6 6 6 0 Vacuolar sorting protein 39 domain 1 TPR_8 PF13181.6 KSA00391.1 - 0.035 14.3 8.7 2.3 8.6 0.1 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 KSA00391.1 - 0.037 14.7 0.5 1.1 10.0 0.2 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 KSA00391.1 - 0.042 14.5 3.7 6.5 7.6 0.1 4.5 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 KSA00391.1 - 0.066 13.7 6.3 8.5 7.0 1.3 4.7 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 KSA00391.1 - 0.75 9.7 9.0 12 5.9 0.4 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat Acetyltransf_10 PF13673.7 KSA00392.1 - 0.032 14.2 0.0 0.19 11.6 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KSA00392.1 - 0.033 14.2 0.0 0.082 13.0 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ubiq_cyt_C_chap PF03981.12 KSA00393.1 - 7.4e-40 136.3 0.4 1.2e-39 135.6 0.1 1.4 2 0 0 2 2 2 1 Ubiquinol-cytochrome C chaperone BLYB PF05289.11 KSA00393.1 - 0.011 15.9 0.0 0.023 14.9 0.0 1.4 1 0 0 1 1 1 0 Borrelia hemolysin accessory protein DUF4998 PF16389.5 KSA00393.1 - 0.063 12.9 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function adh_short PF00106.25 KSA00394.1 - 6.5e-36 123.6 0.5 7.9e-36 123.3 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KSA00394.1 - 5.7e-31 107.9 0.0 6.9e-31 107.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KSA00394.1 - 1.3e-12 48.0 0.0 1.8e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KSA00394.1 - 2.3e-07 30.9 0.0 3.2e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KSA00394.1 - 2.5e-05 23.6 0.7 4.6e-05 22.7 0.7 1.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KSA00394.1 - 0.00013 21.5 0.1 0.00019 20.9 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KSA00394.1 - 0.0069 15.8 0.2 0.014 14.8 0.2 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase F420_oxidored PF03807.17 KSA00394.1 - 0.12 13.0 0.6 0.33 11.6 0.1 2.1 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent zf-RING_UBOX PF13445.6 KSA00395.1 - 4.2e-08 33.1 8.8 4.2e-08 33.1 8.8 2.8 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KSA00395.1 - 4.4e-06 26.5 5.8 4.4e-06 26.5 5.8 3.4 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KSA00395.1 - 6.1e-06 26.3 7.6 6.1e-06 26.3 7.6 2.8 2 1 1 3 3 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 KSA00395.1 - 3.5e-05 23.5 7.0 3.5e-05 23.5 7.0 3.3 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KSA00395.1 - 0.0001 22.5 5.1 0.0001 22.5 5.1 4.2 4 0 0 4 4 4 1 Ring finger domain zf-C3HC4_3 PF13920.6 KSA00395.1 - 0.00021 21.1 2.7 0.00021 21.1 2.7 3.8 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KSA00395.1 - 0.00021 21.2 6.0 0.00021 21.2 6.0 3.0 2 1 0 2 2 1 1 zinc-RING finger domain zf-Nse PF11789.8 KSA00395.1 - 0.00047 19.9 2.1 0.00047 19.9 2.1 2.3 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit Sina PF03145.16 KSA00395.1 - 0.009 16.0 7.0 0.009 16.0 7.0 3.2 2 1 1 3 3 3 1 Seven in absentia protein family CCDC106 PF15794.5 KSA00395.1 - 0.016 14.9 0.2 0.042 13.6 0.2 1.7 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Csm1_N PF18504.1 KSA00395.1 - 0.017 15.5 1.3 0.75 10.2 0.1 2.9 2 0 0 2 2 2 0 Csm1 N-terminal domain DUF1272 PF06906.11 KSA00395.1 - 6.3 7.0 15.9 7.8 6.7 5.5 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) Prok-RING_4 PF14447.6 KSA00395.1 - 9.6 6.2 13.8 41 4.1 0.5 3.7 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 Oxysterol_BP PF01237.18 KSA00396.1 - 3.3e-100 335.5 0.0 7.3e-100 334.4 0.0 1.6 1 1 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.6 KSA00396.1 - 5.2e-36 122.8 0.2 1.1e-35 121.7 0.2 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KSA00396.1 - 0.002 18.6 0.2 0.016 15.7 0.2 2.7 1 0 0 1 1 1 1 PH domain MFS_1 PF07690.16 KSA00397.1 - 2.4e-44 151.7 57.1 2.7e-35 122.0 22.0 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KSA00397.1 - 1.5e-11 43.8 9.9 1.5e-11 43.8 9.9 2.8 2 1 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 KSA00397.1 - 0.0037 15.6 3.6 0.0037 15.6 3.6 2.9 3 1 0 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family PUNUT PF16913.5 KSA00398.1 - 6.6e-08 32.1 18.5 6.7e-08 32.1 6.1 3.2 2 1 1 3 3 3 3 Purine nucleobase transmembrane transport EamA PF00892.20 KSA00398.1 - 1.9e-07 31.3 30.2 8.9e-06 25.9 4.6 3.4 3 1 0 3 3 3 2 EamA-like transporter family DIOX_N PF14226.6 KSA00399.1 - 1.3e-18 67.9 0.0 2.3e-18 67.1 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KSA00399.1 - 5.2e-13 49.4 0.0 1.2e-12 48.2 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TauD PF02668.16 KSA00399.1 - 0.056 13.2 0.0 0.089 12.6 0.0 1.3 1 0 0 1 1 1 0 Taurine catabolism dioxygenase TauD, TfdA family RNase_H2_suC PF08615.11 KSA00400.1 - 4.4e-21 75.5 0.1 1.2e-20 74.1 0.1 1.6 1 1 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Rad4 PF03835.15 KSA00401.1 - 4.3e-32 110.8 1.7 4.5e-32 110.8 0.0 1.9 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 KSA00401.1 - 6.5e-17 61.7 0.1 9.6e-16 58.0 0.0 2.6 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 3 BHD_2 PF10404.9 KSA00401.1 - 5.2e-12 46.5 0.2 2.3e-11 44.5 0.0 2.2 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 2 BHD_1 PF10403.9 KSA00401.1 - 6.7e-09 35.5 0.2 1.5e-08 34.4 0.2 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 Transglut_core PF01841.19 KSA00401.1 - 0.028 14.9 0.0 0.089 13.3 0.0 1.8 1 0 0 1 1 1 0 Transglutaminase-like superfamily DUF2045 PF09741.9 KSA00401.1 - 0.067 12.6 0.7 0.14 11.6 0.1 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2045) RSN1_7TM PF02714.15 KSA00402.1 - 1.6e-82 276.9 26.0 3e-82 276.0 26.0 1.5 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 KSA00402.1 - 5.3e-17 62.6 0.0 8.8e-17 61.9 0.0 1.4 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 KSA00402.1 - 1e-10 41.6 0.0 1.7e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter Met_10 PF02475.16 KSA00403.1 - 3.1e-72 242.5 0.1 4.4e-72 242.0 0.1 1.2 1 0 0 1 1 1 1 Met-10+ like-protein MethyltransfD12 PF02086.15 KSA00403.1 - 0.012 15.3 0.4 0.03 14.0 0.1 1.8 2 0 0 2 2 2 0 D12 class N6 adenine-specific DNA methyltransferase MBG PF17883.1 KSA00403.1 - 0.077 13.6 0.7 4.8 7.8 0.0 2.5 2 0 0 2 2 2 0 MBG domain TRM PF02005.16 KSA00403.1 - 0.097 11.8 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase ECR1_N PF14382.6 KSA00404.1 - 1.1e-15 57.1 0.0 2.7e-15 55.9 0.0 1.7 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 KSA00404.1 - 8.7e-10 38.8 0.2 1.9e-09 37.7 0.2 1.6 1 0 0 1 1 1 1 KH domain EMP24_GP25L PF01105.24 KSA00405.1 - 2.5e-18 66.7 9.7 6.2e-18 65.4 9.7 1.6 1 1 0 1 1 1 1 emp24/gp25L/p24 family/GOLD PCRF PF03462.18 KSA00406.1 - 2.2e-50 171.2 0.6 5.1e-50 170.0 0.0 1.8 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 KSA00406.1 - 2.9e-35 120.7 3.7 2.9e-35 120.7 3.7 2.0 2 0 0 2 2 2 1 RF-1 domain DUF4140 PF13600.6 KSA00406.1 - 0.0063 16.9 1.2 2.2 8.8 0.3 3.0 2 1 0 2 2 2 2 N-terminal domain of unknown function (DUF4140) MIR PF02815.19 KSA00406.1 - 0.14 12.0 0.9 0.35 10.7 0.1 2.0 2 1 0 2 2 2 0 MIR domain Atg14 PF10186.9 KSA00407.1 - 0.029 13.5 3.2 0.031 13.4 3.2 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 PEPcase PF00311.17 KSA00407.1 - 0.054 11.6 0.9 0.053 11.6 0.9 1.0 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase Herpes_UL6 PF01763.16 KSA00407.1 - 0.066 11.7 3.1 0.071 11.6 3.1 1.0 1 0 0 1 1 1 0 Herpesvirus UL6 like IL11 PF07400.11 KSA00407.1 - 0.094 12.4 0.7 0.22 11.2 0.2 1.6 1 1 1 2 2 2 0 Interleukin 11 ZapB PF06005.12 KSA00407.1 - 0.17 12.3 6.8 0.39 11.2 6.9 1.7 1 1 0 1 1 1 0 Cell division protein ZapB JIP_LZII PF16471.5 KSA00407.1 - 0.19 11.9 9.5 0.092 12.9 2.9 2.1 1 1 1 2 2 2 0 JNK-interacting protein leucine zipper II DUF1664 PF07889.12 KSA00407.1 - 0.64 10.1 4.4 1.2 9.2 4.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DivIC PF04977.15 KSA00407.1 - 1.1 9.0 5.2 0.34 10.7 1.1 2.1 1 1 1 2 2 2 0 Septum formation initiator Methyltransf_23 PF13489.6 KSA00408.1 - 9.1e-22 77.6 0.0 1.9e-21 76.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KSA00408.1 - 1.9e-14 54.1 0.0 3.4e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KSA00408.1 - 2.3e-13 50.7 0.0 4.4e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KSA00408.1 - 4.1e-11 42.7 0.0 6.8e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 KSA00408.1 - 6.6e-11 42.7 0.0 1.1e-10 42.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KSA00408.1 - 1.1e-10 41.5 0.0 1.8e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain RPN6_N PF18055.1 KSA00409.1 - 6.7e-37 126.4 3.4 6.7e-37 126.4 3.4 2.7 3 0 0 3 3 2 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 KSA00409.1 - 1e-17 64.5 1.3 2.2e-17 63.5 0.2 2.2 2 0 0 2 2 2 1 PCI domain RPN6_C_helix PF18503.1 KSA00409.1 - 3.1e-09 36.4 0.1 8.5e-09 35.0 0.1 1.8 1 0 0 1 1 1 1 26S proteasome subunit RPN6 C-terminal helix domain TPR_MalT PF17874.1 KSA00409.1 - 2.8e-05 23.7 3.2 0.00011 21.7 1.4 2.1 2 0 0 2 2 2 1 MalT-like TPR region TPR_12 PF13424.6 KSA00409.1 - 0.0003 21.0 7.5 0.14 12.5 0.8 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 KSA00409.1 - 0.0014 18.5 0.3 2.2 8.5 0.0 4.5 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 KSA00409.1 - 0.0028 17.7 3.0 6.9 7.0 0.0 5.2 5 1 1 6 6 6 1 Tetratricopeptide repeat DDRGK PF09756.9 KSA00409.1 - 0.01 15.5 0.1 0.025 14.2 0.1 1.7 1 0 0 1 1 1 0 DDRGK domain TPR_16 PF13432.6 KSA00409.1 - 0.025 15.2 2.0 6.9 7.4 0.1 3.4 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KSA00409.1 - 0.06 14.2 0.3 52 5.0 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat HBS1_N PF08938.10 KSA00409.1 - 0.069 13.5 0.3 0.26 11.6 0.2 2.1 2 0 0 2 2 2 0 HBS1 N-terminus ANAPC5 PF12862.7 KSA00409.1 - 0.091 12.8 2.4 4.5 7.4 0.1 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 TPR_19 PF14559.6 KSA00409.1 - 0.32 11.5 5.6 3.9 8.0 0.3 4.0 3 2 2 5 5 5 0 Tetratricopeptide repeat TPR_20 PF14561.6 KSA00409.1 - 1 9.7 4.8 0.4 11.0 0.3 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 KSA00409.1 - 3.7 8.4 8.2 25 5.8 0.4 5.1 6 1 0 6 6 5 0 Tetratricopeptide repeat Nup84_Nup100 PF04121.13 KSA00410.1 - 4.4e-190 633.4 17.2 5.1e-190 633.2 17.2 1.0 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 PX PF00787.24 KSA00411.1 - 5.7e-20 71.4 1.1 8.9e-20 70.8 0.1 1.9 2 0 0 2 2 2 1 PX domain IFT20 PF14931.6 KSA00411.1 - 0.036 14.2 4.8 1.8 8.7 0.1 2.6 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 Tn7_Tnp_TnsA_C PF08721.11 KSA00411.1 - 7.6 7.2 8.7 2.7 8.7 0.1 4.0 3 3 1 4 4 4 0 TnsA endonuclease C terminal DUF3445 PF11927.8 KSA00412.1 - 1.5e-68 230.8 0.0 1.9e-68 230.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) SpoU_methylase PF00588.19 KSA00413.1 - 9.2e-27 94.0 0.0 2.4e-26 92.6 0.0 1.8 1 0 0 1 1 1 1 SpoU rRNA Methylase family SapB_2 PF03489.17 KSA00413.1 - 0.14 12.3 0.7 15 5.8 0.1 3.2 2 0 0 2 2 2 0 Saposin-like type B, region 2 RNase_PH PF01138.21 KSA00414.1 - 3e-10 40.7 0.0 5.4e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KSA00414.1 - 0.00033 20.6 0.0 0.00091 19.2 0.0 1.8 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Nup35_RRM PF05172.13 KSA00415.1 - 3.6e-23 81.4 0.3 1.7e-22 79.3 0.2 2.0 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 KSA00415.1 - 0.00013 21.9 0.0 0.00036 20.5 0.0 1.8 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif DUF2418 PF10332.9 KSA00416.1 - 3.7e-26 91.5 3.9 1e-25 90.1 3.9 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2418) TolA_bind_tri PF16331.5 KSA00417.1 - 0.0025 17.9 10.3 0.0025 17.9 10.3 2.8 1 1 1 2 2 2 2 TolA binding protein trimerisation Y_phosphatase PF00102.27 KSA00418.1 - 8.5e-56 189.1 0.5 1.6e-55 188.2 0.5 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.20 KSA00418.1 - 3e-06 27.7 0.0 8.3e-06 26.3 0.0 1.8 1 0 0 1 1 1 1 Rhodanese-like domain DSPc PF00782.20 KSA00418.1 - 4.5e-05 23.3 0.2 0.00024 20.9 0.0 2.3 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KSA00418.1 - 0.026 14.5 0.0 0.042 13.8 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Prenyltrans PF00432.21 KSA00419.1 - 3.2e-26 90.7 9.2 1.8e-07 30.7 0.0 5.1 5 0 0 5 5 5 4 Prenyltransferase and squalene oxidase repeat HGTP_anticodon PF03129.20 KSA00420.1 - 9.7e-23 80.1 0.1 2.5e-22 78.8 0.1 1.8 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 KSA00420.1 - 6.2e-09 36.1 0.0 1.7e-08 34.7 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) D5_N PF08706.11 KSA00420.1 - 0.068 13.4 0.6 0.17 12.2 0.6 1.6 1 0 0 1 1 1 0 D5 N terminal like Raptor_N PF14538.6 KSA00421.1 - 7.5e-67 223.9 0.0 1.6e-66 222.8 0.0 1.6 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.32 KSA00421.1 - 4.3e-07 30.5 8.4 1.3 10.0 0.0 6.9 7 0 0 7 7 7 3 WD domain, G-beta repeat HEAT PF02985.22 KSA00421.1 - 8.9e-07 28.7 0.5 0.22 11.9 0.0 5.0 5 0 0 5 5 5 2 HEAT repeat Cnd1 PF12717.7 KSA00421.1 - 0.0052 16.9 0.1 0.16 12.0 0.0 2.7 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 ANAPC4_WD40 PF12894.7 KSA00421.1 - 0.016 15.5 0.3 6.6 7.1 0.2 3.7 2 2 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain HEAT_2 PF13646.6 KSA00421.1 - 0.022 15.1 0.0 1.3 9.4 0.0 2.7 1 1 1 2 2 2 0 HEAT repeats Mito_carr PF00153.27 KSA00422.1 - 6.7e-66 218.3 0.5 4.6e-24 84.2 0.0 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein ApoO PF09769.9 KSA00424.1 - 3.3e-40 137.1 0.5 3.8e-38 130.4 0.1 2.3 2 0 0 2 2 2 2 Apolipoprotein O YlqD PF11068.8 KSA00424.1 - 0.037 14.4 6.0 0.17 12.3 3.0 2.1 2 0 0 2 2 2 0 YlqD protein Rsm22 PF09243.10 KSA00425.1 - 2.8e-24 85.8 1.1 1.1e-06 28.2 0.0 4.4 3 1 0 4 4 4 4 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_23 PF13489.6 KSA00425.1 - 1.5e-05 24.9 0.0 4.3e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KSA00425.1 - 0.028 15.1 0.0 0.12 13.1 0.0 2.2 1 0 0 1 1 1 0 Methyltransferase domain Ribosomal_S27e PF01667.17 KSA00426.1 - 8.5e-29 99.0 4.7 1.1e-28 98.7 4.7 1.2 1 0 0 1 1 1 1 Ribosomal protein S27 HisKA PF00512.25 KSA00427.1 - 0.18 11.9 0.5 0.49 10.5 0.0 2.0 2 0 0 2 2 2 0 His Kinase A (phospho-acceptor) domain F-box-like PF12937.7 KSA00428.1 - 6.3e-06 26.0 0.0 1.1e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 F-box-like LRR_5 PF13306.6 KSA00428.1 - 0.057 13.4 2.9 0.41 10.6 0.1 3.2 3 2 0 3 3 3 0 BspA type Leucine rich repeat region (6 copies) PMT PF02366.18 KSA00429.1 - 4.2e-72 242.7 11.5 4.2e-72 242.7 11.5 1.9 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KSA00429.1 - 2e-53 181.0 11.9 2e-53 181.0 11.9 2.0 2 0 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KSA00429.1 - 3.1e-24 85.8 0.3 5e-24 85.2 0.3 1.4 1 0 0 1 1 1 1 MIR domain Ins145_P3_rec PF08709.11 KSA00429.1 - 0.015 14.5 0.2 0.32 10.2 0.0 2.1 1 1 1 2 2 2 0 Inositol 1,4,5-trisphosphate/ryanodine receptor RicinB_lectin_2 PF14200.6 KSA00429.1 - 0.022 15.5 0.5 0.17 12.6 0.2 2.4 2 1 1 3 3 3 0 Ricin-type beta-trefoil lectin domain-like Mucin_bdg PF03272.13 KSA00429.1 - 0.024 14.7 0.6 3.9 7.5 0.2 2.4 1 1 1 2 2 2 0 Putative mucin or carbohydrate-binding module Med21 PF11221.8 KSA00430.1 - 1.7e-50 171.1 2.0 2.2e-50 170.6 2.0 1.2 1 0 0 1 1 1 1 Subunit 21 of Mediator complex Spore_III_AB PF09548.10 KSA00430.1 - 0.0061 16.7 0.2 0.0092 16.1 0.2 1.3 1 0 0 1 1 1 1 Stage III sporulation protein AB (spore_III_AB) Med9 PF07544.13 KSA00430.1 - 0.0062 16.6 0.4 0.016 15.3 0.4 1.9 1 1 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 FliD_N PF02465.18 KSA00430.1 - 0.21 12.3 0.4 0.21 12.3 0.4 2.3 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus FYVE PF01363.21 KSA00431.1 - 6.1e-18 64.7 7.5 6.1e-18 64.7 7.5 2.6 3 0 0 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.6 KSA00431.1 - 6e-09 36.1 2.6 6e-09 36.1 2.6 4.2 4 0 0 4 4 4 1 Ring finger domain zf-RING_11 PF17123.5 KSA00431.1 - 3.8e-07 29.7 3.5 3.8e-07 29.7 3.5 2.3 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KSA00431.1 - 5.6e-05 22.9 2.4 5.6e-05 22.9 2.4 4.2 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KSA00431.1 - 0.00033 20.5 1.8 0.00033 20.5 1.8 4.1 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KSA00431.1 - 0.0012 18.4 2.7 0.0012 18.4 2.7 3.4 3 0 0 3 3 3 1 Zinc-ribbon, C4HC2 type zf-rbx1 PF12678.7 KSA00431.1 - 0.0052 17.1 2.6 0.0052 17.1 2.6 3.3 3 1 0 3 3 3 1 RING-H2 zinc finger domain zf-Di19 PF05605.12 KSA00431.1 - 0.14 12.5 6.3 0.28 11.5 0.0 3.0 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding DEAD PF00270.29 KSA00432.1 - 2.1e-50 170.9 0.0 4.2e-50 169.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KSA00432.1 - 2e-31 108.6 0.0 6e-31 107.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KSA00432.1 - 4.1e-08 33.4 0.0 9.9e-08 32.2 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KSA00432.1 - 0.00059 19.6 0.0 0.0014 18.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain Brix PF04427.18 KSA00433.1 - 1.9e-47 161.9 2.1 2.7e-47 161.4 2.1 1.2 1 0 0 1 1 1 1 Brix domain Borrelia_P83 PF05262.11 KSA00433.1 - 0.48 8.9 23.3 0.76 8.2 23.3 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein CBP4 PF07960.11 KSA00433.1 - 0.9 9.4 10.9 2.1 8.2 10.9 1.6 1 0 0 1 1 1 0 CBP4 DUF4775 PF16001.5 KSA00433.1 - 2.2 7.6 25.7 3.9 6.8 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4775) DDRGK PF09756.9 KSA00433.1 - 4 7.0 25.2 2.9 7.4 20.2 2.4 2 0 0 2 2 2 0 DDRGK domain ALMT PF11744.8 KSA00433.1 - 9.5 4.9 8.2 16 4.2 8.2 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter NUDIX PF00293.28 KSA00435.1 - 1.3e-10 41.5 0.0 4e-10 39.8 0.0 1.9 1 1 0 1 1 1 1 NUDIX domain NAD_Gly3P_dh_N PF01210.23 KSA00436.1 - 1.7e-52 177.6 0.3 3.5e-52 176.5 0.3 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 KSA00436.1 - 3.3e-40 137.7 0.1 6.6e-40 136.7 0.1 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.17 KSA00436.1 - 0.00032 21.2 0.2 0.012 16.2 0.2 2.6 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Fungal_trans PF04082.18 KSA00437.1 - 6e-12 45.2 0.1 1.1e-11 44.3 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KSA00437.1 - 2.1e-06 27.8 8.7 3.5e-06 27.0 8.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SSF PF00474.17 KSA00438.1 - 1.9e-11 43.5 20.0 1.9e-11 43.5 20.0 1.7 2 0 0 2 2 2 1 Sodium:solute symporter family Amidase PF01425.21 KSA00439.1 - 1.5e-93 314.2 0.0 2e-93 313.8 0.0 1.1 1 0 0 1 1 1 1 Amidase Staph_haemo PF05480.11 KSA00439.1 - 0.16 11.8 0.1 0.36 10.6 0.1 1.5 1 0 0 1 1 1 0 Staphylococcus haemolytic protein CCDC-167 PF15188.6 KSA00440.1 - 0.18 12.2 8.0 0.47 10.8 8.0 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 DUF3018 PF11455.8 KSA00440.1 - 4.3 7.3 8.8 0.13 12.2 1.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3018) Carb_kinase PF01256.17 KSA00441.1 - 2.9e-52 177.6 0.0 3.1e-50 170.9 0.0 2.1 1 1 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.12 KSA00441.1 - 0.00051 19.5 0.0 0.014 14.8 0.0 2.1 2 0 0 2 2 2 2 Phosphomethylpyrimidine kinase NAD_binding_1 PF00175.21 KSA00442.1 - 2.3e-30 105.4 0.0 4.1e-30 104.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KSA00442.1 - 2.6e-23 82.2 0.0 4.7e-23 81.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KSA00442.1 - 1.7e-06 28.2 0.0 0.00042 20.5 0.0 2.5 2 0 0 2 2 2 2 Ferric reductase NAD binding domain DBR1 PF05011.13 KSA00443.1 - 2.4e-23 83.1 0.9 2.4e-23 83.1 0.9 2.0 2 0 0 2 2 2 1 Lariat debranching enzyme, C-terminal domain Rota_NSP3 PF01665.16 KSA00443.1 - 0.033 13.3 4.2 0.024 13.8 2.2 1.8 2 0 0 2 2 2 0 Rotavirus non-structural protein NSP3 ApbA PF02558.16 KSA00444.1 - 1.4e-28 99.5 0.0 2e-28 99.0 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 KSA00444.1 - 3.4e-28 98.4 0.0 9.2e-28 96.9 0.0 1.7 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal DAO PF01266.24 KSA00444.1 - 0.014 15.0 0.1 0.022 14.4 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 KSA00444.1 - 0.057 13.9 0.0 0.17 12.3 0.0 1.8 2 0 0 2 2 2 0 Putative NAD(P)-binding AP_endonuc_2 PF01261.24 KSA00444.1 - 0.079 12.4 0.0 0.27 10.7 0.0 1.8 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel ThiF PF00899.21 KSA00444.1 - 0.081 12.3 0.1 0.4 10.0 0.2 2.1 3 0 0 3 3 3 0 ThiF family FAD_binding_3 PF01494.19 KSA00444.1 - 0.086 12.1 0.3 0.13 11.5 0.3 1.3 1 0 0 1 1 1 0 FAD binding domain PI3_PI4_kinase PF00454.27 KSA00445.1 - 1e-45 156.5 0.1 1.9e-45 155.7 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase MscS_TM PF12794.7 KSA00445.1 - 0.074 11.9 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 TolB_N PF04052.13 KSA00446.1 - 0.023 14.9 0.3 0.054 13.7 0.3 1.7 1 1 0 1 1 1 0 TolB amino-terminal domain Baculo_VP39 PF04501.12 KSA00446.1 - 0.25 10.8 1.7 1.7 8.1 0.0 2.5 3 0 0 3 3 3 0 Baculovirus major capsid protein VP39 SPX PF03105.19 KSA00448.1 - 3e-48 165.7 16.1 4e-48 165.3 16.1 1.2 1 0 0 1 1 1 1 SPX domain Na_sulph_symp PF00939.19 KSA00448.1 - 3.6e-27 95.5 45.0 5.1e-27 95.0 45.0 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 KSA00448.1 - 7.2e-27 94.4 37.4 7.2e-27 94.4 37.4 2.0 2 0 0 2 2 2 1 Citrate transporter PBP1_TM PF14812.6 KSA00448.1 - 0.0034 17.7 2.7 0.0034 17.7 2.7 2.1 2 0 0 2 2 2 1 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.10 KSA00448.1 - 2.5 8.5 12.5 6.1 7.3 12.5 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Peptidase_M20 PF01546.28 KSA00449.1 - 7.3e-23 81.3 0.0 1.1e-22 80.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KSA00449.1 - 2.6e-10 40.2 0.0 5.1e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain WD40 PF00400.32 KSA00449.1 - 2.9e-05 24.7 15.3 0.011 16.6 0.2 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat SAM35 PF10806.8 KSA00449.1 - 0.069 13.4 0.0 15 5.9 0.0 2.6 2 0 0 2 2 2 0 SAM35, subunit of SAM coomplex UPF0370 PF13980.6 KSA00450.1 - 0.069 13.2 0.6 7.1 6.7 0.1 2.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0370) zf-C3HC4_3 PF13920.6 KSA00450.1 - 0.73 9.7 8.7 1.2 9.0 4.5 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KSA00450.1 - 7.6 7.0 10.7 5.2 7.5 6.1 2.2 2 0 0 2 2 2 0 Ring finger domain DUF4064 PF13273.6 KSA00451.1 - 0.28 11.5 2.0 0.69 10.2 2.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) Serglycin PF04360.12 KSA00452.1 - 0.00044 20.2 4.7 0.00097 19.1 4.7 1.6 1 0 0 1 1 1 1 Serglycin CdiI_3 PF18616.1 KSA00452.1 - 0.0085 16.0 0.5 0.12 12.3 0.2 2.4 2 0 0 2 2 2 1 CDI immunity proteins FliG_M PF14841.6 KSA00452.1 - 0.093 13.0 0.5 1.3 9.3 0.1 2.7 3 0 0 3 3 3 0 FliG middle domain DUF3600 PF12207.8 KSA00452.1 - 0.14 12.1 0.7 0.26 11.2 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3600) HTH_9 PF08221.11 KSA00452.1 - 1.4 9.1 3.8 1.8 8.7 0.1 2.9 3 1 0 3 3 3 0 RNA polymerase III subunit RPC82 helix-turn-helix domain CDC27 PF09507.10 KSA00453.1 - 2.1e-17 63.7 28.1 6.5e-16 58.7 20.4 2.3 1 1 1 2 2 2 2 DNA polymerase subunit Cdc27 Pirin PF02678.16 KSA00454.1 - 1.8e-28 98.7 0.0 3.3e-28 97.8 0.0 1.5 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 KSA00454.1 - 2.2e-23 82.6 0.0 4.9e-23 81.5 0.0 1.6 1 0 0 1 1 1 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 KSA00454.1 - 0.015 15.0 0.1 0.3 10.9 0.1 2.4 2 0 0 2 2 2 0 Cupin domain Methyltransf_11 PF08241.12 KSA00455.1 - 1.4e-19 70.5 0.0 3e-19 69.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KSA00455.1 - 1.2e-17 64.4 0.0 3.1e-17 63.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KSA00455.1 - 4.6e-11 42.7 0.0 6.4e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KSA00455.1 - 5.3e-11 42.3 0.0 7.4e-11 41.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KSA00455.1 - 1.6e-10 41.6 0.0 2.8e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KSA00455.1 - 1.7e-07 31.3 0.0 2.6e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KSA00455.1 - 0.00018 21.1 0.0 0.00046 19.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain DREV PF05219.12 KSA00455.1 - 0.00034 19.8 0.0 0.00057 19.1 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_PK PF05891.12 KSA00455.1 - 0.0019 17.8 0.0 0.0038 16.8 0.0 1.4 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_32 PF13679.6 KSA00455.1 - 0.0048 16.9 0.0 0.0066 16.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KSA00455.1 - 0.012 15.0 0.0 0.029 13.7 0.0 1.7 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase PrmA PF06325.13 KSA00455.1 - 0.022 14.1 0.0 0.031 13.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.7 KSA00455.1 - 0.038 13.9 0.0 0.062 13.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain NodS PF05401.11 KSA00455.1 - 0.07 12.7 0.0 0.097 12.3 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) tRNA_U5-meth_tr PF05958.11 KSA00455.1 - 0.07 12.1 0.0 0.14 11.1 0.0 1.4 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase FA_hydroxylase PF04116.13 KSA00456.1 - 2.1e-23 83.1 12.7 2.5e-23 82.9 7.3 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF5028 PF16431.5 KSA00456.1 - 0.02 14.9 0.0 0.032 14.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5028) Wzy_C_2 PF11846.8 KSA00456.1 - 0.031 14.2 0.0 0.058 13.3 0.0 1.4 1 0 0 1 1 1 0 Virulence factor membrane-bound polymerase, C-terminal DUF4381 PF14316.6 KSA00456.1 - 0.22 11.8 1.0 0.49 10.6 1.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) TRAPP PF04051.16 KSA00457.1 - 8.2e-26 90.5 0.1 9.3e-26 90.3 0.1 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Dsl1_N PF11988.8 KSA00457.1 - 0.027 13.4 0.1 0.042 12.8 0.0 1.3 1 1 0 1 1 1 0 Retrograde transport protein Dsl1 N terminal TetR_C_4 PF08359.11 KSA00457.1 - 0.056 13.6 0.5 1.9 8.6 0.0 2.2 1 1 1 2 2 2 0 YsiA-like protein, C-terminal region Acyltransferase PF01553.21 KSA00458.1 - 6e-10 38.9 0.0 0.0013 18.3 0.0 2.4 2 0 0 2 2 2 2 Acyltransferase Spt5_N PF11942.8 KSA00458.1 - 0.36 11.8 4.9 1.2 10.2 4.9 1.9 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal ABC2_membrane_3 PF12698.7 KSA00458.1 - 0.37 9.9 6.4 0.056 12.5 1.3 2.0 2 0 0 2 2 2 0 ABC-2 family transporter protein Sigma70_ner PF04546.13 KSA00458.1 - 1.1 9.2 5.8 1.4 8.7 2.8 2.4 2 0 0 2 2 2 0 Sigma-70, non-essential region zf-AN1 PF01428.16 KSA00460.1 - 4.6e-11 42.7 5.2 4.6e-11 42.7 5.2 1.5 1 1 0 1 1 1 1 AN1-like Zinc finger Ubiquitin_4 PF18036.1 KSA00460.1 - 7e-05 22.8 0.0 0.51 10.4 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin-like domain ubiquitin PF00240.23 KSA00460.1 - 0.00087 19.0 0.0 0.0022 17.7 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KSA00460.1 - 0.012 15.5 0.0 0.024 14.4 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Fe_dep_repr_C PF02742.15 KSA00460.1 - 0.076 13.1 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 Iron dependent repressor, metal binding and dimerisation domain Transp_Tc5_C PF04236.15 KSA00460.1 - 0.12 12.8 4.7 0.23 11.8 4.7 1.5 1 0 0 1 1 1 0 Tc5 transposase C-terminal domain CLCA PF08434.11 KSA00460.1 - 0.86 8.9 4.4 1.5 8.0 4.4 1.4 1 0 0 1 1 1 0 Calcium-activated chloride channel N terminal Nro1 PF12753.7 KSA00461.1 - 8.7e-174 578.3 25.9 9.8e-174 578.1 25.9 1.0 1 0 0 1 1 1 1 Nuclear pore complex subunit Nro1 DUF4682 PF15733.5 KSA00461.1 - 9.6 6.8 7.8 6.2 7.4 4.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4682) TP_methylase PF00590.20 KSA00462.1 - 5.3e-43 147.4 0.0 8.1e-43 146.8 0.0 1.3 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.6 KSA00462.1 - 1.2e-17 64.2 0.0 2.5e-17 63.2 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_M PF14824.6 KSA00462.1 - 7.9e-06 25.2 0.0 1.6e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Sirohm_synth_C PF14823.6 KSA00462.1 - 0.001 18.7 0.2 0.16 11.6 0.0 2.7 3 0 0 3 3 3 1 Sirohaem biosynthesis protein C-terminal BID PF06393.11 KSA00462.1 - 0.011 15.3 0.4 0.043 13.4 0.1 1.9 2 0 0 2 2 2 0 BH3 interacting domain (BID) DUF29 PF01724.16 KSA00462.1 - 0.073 13.3 0.7 0.19 11.9 0.7 1.7 1 0 0 1 1 1 0 Domain of unknown function DUF29 LMBR1 PF04791.16 KSA00462.1 - 0.091 11.7 0.3 0.12 11.3 0.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Shikimate_DH PF01488.20 KSA00462.1 - 0.14 12.2 0.0 0.47 10.5 0.0 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Hydrolase_6 PF13344.6 KSA00463.1 - 2.2e-24 85.5 0.0 4.9e-24 84.4 0.0 1.6 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KSA00463.1 - 2.3e-22 78.9 0.0 1.8e-20 72.8 0.0 2.5 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 KSA00463.1 - 2.9e-05 24.5 0.0 4.8 7.4 0.0 3.6 3 1 0 3 3 3 3 haloacid dehalogenase-like hydrolase GATA PF00320.27 KSA00464.1 - 1.1e-14 53.8 4.1 1.8e-14 53.0 4.1 1.4 1 0 0 1 1 1 1 GATA zinc finger OrfB_Zn_ribbon PF07282.11 KSA00464.1 - 0.059 13.3 0.5 0.26 11.2 0.4 2.0 2 0 0 2 2 2 0 Putative transposase DNA-binding domain DZR PF12773.7 KSA00464.1 - 0.11 12.5 0.4 0.23 11.5 0.4 1.5 1 0 0 1 1 1 0 Double zinc ribbon NDUF_B7 PF05676.13 KSA00465.1 - 1.1e-13 50.7 2.9 1.3e-13 50.4 2.9 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) COX6B PF02297.17 KSA00465.1 - 0.014 15.6 5.9 0.14 12.4 5.9 2.0 1 1 0 1 1 1 0 Cytochrome oxidase c subunit VIb NDUF_B7 PF05676.13 KSA00466.1 - 2.3e-20 72.1 4.1 2.8e-20 71.8 4.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) COX6B PF02297.17 KSA00466.1 - 0.075 13.3 4.8 0.11 12.8 4.8 1.3 1 1 0 1 1 1 0 Cytochrome oxidase c subunit VIb CUE PF02845.16 KSA00467.1 - 8.7e-12 44.5 0.0 1.7e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 CUE domain Glyoxalase PF00903.25 KSA00468.1 - 6.2e-08 32.9 0.0 5.9e-07 29.7 0.0 2.0 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 KSA00468.1 - 0.00022 21.1 0.0 0.0011 18.9 0.0 1.9 1 1 0 1 1 1 1 Glyoxalase-like domain TALPID3 PF15324.6 KSA00470.1 - 0.93 7.1 7.0 0.88 7.2 7.0 1.0 1 0 0 1 1 1 0 Hedgehog signalling target adh_short PF00106.25 KSA00471.1 - 2.2e-08 33.8 0.0 1.6e-07 31.0 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KSA00471.1 - 2.5e-05 23.9 0.0 0.00013 21.6 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KSA00471.1 - 0.00071 19.1 0.0 0.0013 18.2 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 KSA00471.1 - 0.0072 16.2 0.1 0.012 15.5 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.24 KSA00471.1 - 0.017 15.5 0.0 0.27 11.7 0.1 2.4 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.10 KSA00471.1 - 0.021 14.7 1.3 0.081 12.8 1.3 1.8 1 1 0 1 1 1 0 KR domain DFP PF04127.15 KSA00471.1 - 0.04 13.8 0.1 0.12 12.1 0.0 1.7 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein 2-Hacid_dh_C PF02826.19 KSA00471.1 - 0.04 13.3 0.0 0.058 12.7 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NmrA PF05368.13 KSA00471.1 - 0.041 13.4 0.7 0.094 12.3 0.6 1.6 1 1 1 2 2 2 0 NmrA-like family NAD_binding_10 PF13460.6 KSA00471.1 - 0.079 12.8 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding Ecm29 PF13001.7 KSA00472.1 - 9.8e-146 486.3 5.6 9.8e-146 486.3 5.6 3.3 4 0 0 4 4 4 1 Proteasome stabiliser HEAT PF02985.22 KSA00472.1 - 2.1e-06 27.5 1.4 0.54 10.7 0.0 7.1 8 0 0 8 8 8 2 HEAT repeat Vac14_Fab1_bd PF12755.7 KSA00472.1 - 7.8e-06 26.4 0.5 0.17 12.5 0.0 6.4 6 0 0 6 6 6 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 KSA00472.1 - 5.4e-05 22.9 3.0 0.32 10.5 0.0 5.4 6 1 0 6 6 6 2 CLASP N terminal IF-2B PF01008.17 KSA00473.1 - 3.5e-73 246.3 8.4 1.1e-36 126.6 0.0 2.7 3 0 0 3 3 3 2 Initiation factor 2 subunit family TERB2 PF15101.6 KSA00473.1 - 0.18 11.9 9.7 0.43 10.6 0.4 2.6 2 0 0 2 2 2 0 Telomere-associated protein TERB2 PhoLip_ATPase_C PF16212.5 KSA00474.1 - 6.7e-81 271.7 24.7 6.7e-81 271.7 24.7 2.8 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KSA00474.1 - 8.6e-24 83.0 11.2 2.7e-23 81.4 9.8 2.7 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KSA00474.1 - 5e-11 43.3 1.0 1.9e-05 25.0 0.0 3.4 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KSA00474.1 - 8e-11 41.9 0.0 3.3e-10 39.9 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 KSA00474.1 - 0.00012 21.6 0.0 0.00029 20.4 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KSA00474.1 - 0.013 15.3 0.5 0.013 15.3 0.5 2.6 2 1 1 3 3 3 0 haloacid dehalogenase-like hydrolase Aldedh PF00171.22 KSA00475.1 - 5e-22 78.1 1.8 3e-16 59.0 0.1 2.6 1 1 1 2 2 2 2 Aldehyde dehydrogenase family URO-D PF01208.17 KSA00475.1 - 0.034 13.3 0.0 0.058 12.5 0.0 1.3 1 0 0 1 1 1 0 Uroporphyrinogen decarboxylase (URO-D) DUF1487 PF07368.11 KSA00475.1 - 0.053 13.0 0.1 0.12 11.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) Pex26 PF07163.12 KSA00475.1 - 0.056 12.7 0.7 0.41 9.9 0.4 2.1 2 0 0 2 2 2 0 Pex26 protein DUF4168 PF13767.6 KSA00475.1 - 0.36 12.0 3.3 1.9 9.7 0.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4168) BUD22 PF09073.10 KSA00475.1 - 0.86 8.9 4.5 0.66 9.3 0.4 2.1 2 0 0 2 2 2 0 BUD22 DUF1542 PF07564.11 KSA00475.1 - 0.92 9.7 13.0 0.26 11.4 3.9 2.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) FKBP_N PF01346.18 KSA00475.1 - 3.3 8.8 4.7 15 6.7 0.1 2.7 2 0 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase NAD_binding_7 PF13241.6 KSA00476.1 - 6e-30 103.7 0.0 1.5e-29 102.5 0.0 1.7 2 0 0 2 2 2 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 KSA00476.1 - 1.1e-11 44.2 0.0 2.7e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 KSA00476.1 - 1.4e-10 40.4 0.1 2.8e-10 39.5 0.1 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Shikimate_DH PF01488.20 KSA00476.1 - 0.023 14.7 0.1 0.043 13.9 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase LSDAT_prok PF18171.1 KSA00476.1 - 0.063 12.5 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 SLOG in TRPM, prokaryote Pyr_redox_3 PF13738.6 KSA00476.1 - 0.064 12.5 0.0 0.095 11.9 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.18 KSA00477.1 - 2e-38 132.1 1.9 4.3e-38 131.0 1.9 1.5 1 1 0 1 1 1 1 GDP dissociation inhibitor FAD_binding_3 PF01494.19 KSA00477.1 - 0.025 13.9 0.0 0.048 12.9 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain Ribosomal_L7Ae PF01248.26 KSA00478.1 - 3.9e-25 87.4 0.6 4.9e-25 87.1 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Gin PF10764.9 KSA00478.1 - 0.015 15.3 0.8 0.024 14.6 0.8 1.3 1 0 0 1 1 1 0 Inhibitor of sigma-G Gin SBD_N PF07005.11 KSA00478.1 - 0.041 13.6 0.1 0.05 13.3 0.1 1.1 1 0 0 1 1 1 0 Sugar-binding N-terminal domain NTP_transf_3 PF12804.7 KSA00478.1 - 0.063 13.6 0.1 0.082 13.3 0.1 1.4 1 1 0 1 1 1 0 MobA-like NTP transferase domain KNOX2 PF03791.13 KSA00478.1 - 0.087 12.3 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 KNOX2 domain DUF4763 PF15960.5 KSA00479.1 - 0.0022 17.3 0.5 0.0022 17.3 0.5 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4763) TMPIT PF07851.13 KSA00479.1 - 0.11 11.8 6.3 0.18 11.0 6.3 1.4 1 0 0 1 1 1 0 TMPIT-like protein V-SNARE PF05008.15 KSA00479.1 - 0.11 12.9 2.1 0.18 12.2 0.0 2.4 3 0 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus TMF_TATA_bd PF12325.8 KSA00479.1 - 0.33 11.2 4.7 2.6 8.3 0.1 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding CENP-H PF05837.12 KSA00479.1 - 0.92 9.9 5.2 0.22 12.0 0.8 2.3 2 1 0 2 2 2 0 Centromere protein H (CENP-H) RFX5_DNA_bdg PF14621.6 KSA00479.1 - 1.3 8.7 16.9 18 5.0 14.2 3.4 2 2 2 4 4 4 0 RFX5 DNA-binding domain AT_hook PF02178.19 KSA00479.1 - 2.3 8.4 26.6 0.1 12.5 3.7 3.0 3 0 0 3 3 3 0 AT hook motif Fib_alpha PF08702.10 KSA00479.1 - 5.5 7.2 8.3 8.3 6.6 2.5 2.6 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Cornichon PF03311.14 KSA00480.1 - 5.1e-44 149.5 5.1 5.8e-44 149.3 5.1 1.0 1 0 0 1 1 1 1 Cornichon protein LRR_8 PF13855.6 KSA00481.1 - 4e-10 39.3 71.1 2e-05 24.3 8.2 8.5 5 2 4 9 9 9 6 Leucine rich repeat LRR_9 PF14580.6 KSA00481.1 - 2.9e-07 30.1 33.7 0.04 13.4 3.2 5.4 3 1 1 4 4 4 4 Leucine-rich repeat LRR_4 PF12799.7 KSA00481.1 - 5.1e-07 29.9 88.5 0.00017 21.9 5.7 10.8 5 2 8 14 14 14 10 Leucine Rich repeats (2 copies) DUF5496 PF17600.2 KSA00481.1 - 0.1 12.6 0.1 0.27 11.3 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5496) RRM_1 PF00076.22 KSA00482.1 - 1.4e-41 140.1 0.0 2.1e-17 62.7 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KSA00482.1 - 0.00086 19.4 0.0 0.041 14.0 0.0 3.1 3 0 0 3 3 3 1 RNA recognition motif Nup35_RRM_2 PF14605.6 KSA00482.1 - 0.0012 18.8 0.0 0.039 14.0 0.0 2.9 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 KSA00482.1 - 0.0046 16.5 0.0 0.018 14.6 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KSA00482.1 - 0.013 15.5 0.0 0.039 14.0 0.0 1.8 1 0 0 1 1 1 0 RNA binding motif RRM_occluded PF16842.5 KSA00482.1 - 0.072 13.0 0.0 0.67 9.9 0.0 2.4 2 0 0 2 2 2 0 Occluded RNA-recognition motif Histone PF00125.24 KSA00483.1 - 1.9e-51 173.9 2.4 2.1e-51 173.7 2.4 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KSA00483.1 - 3.5e-06 27.3 0.0 5.3e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KSA00483.1 - 2.6e-05 24.3 0.4 4.3e-05 23.6 0.1 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 KSA00483.1 - 0.00013 22.6 1.2 0.00015 22.4 1.2 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 KSA00483.1 - 0.0012 19.0 0.8 0.0017 18.6 0.1 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KSA00483.1 - 0.023 14.8 0.3 0.035 14.2 0.1 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Oxidored_q6 PF01058.22 KSA00484.1 - 3.1e-22 78.8 0.1 4.4e-22 78.3 0.1 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit EnY2 PF10163.9 KSA00485.1 - 2.3e-28 98.4 0.2 2.8e-28 98.1 0.2 1.1 1 0 0 1 1 1 1 Transcription factor e(y)2 NUDIX PF00293.28 KSA00486.1 - 2.5e-15 56.7 0.0 3.8e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Sec15 PF04091.12 KSA00486.1 - 0.14 11.5 0.0 0.18 11.2 0.0 1.1 1 0 0 1 1 1 0 Exocyst complex subunit Sec15-like FANCL_C PF11793.8 KSA00487.1 - 0.002 18.2 3.9 0.023 14.9 0.2 3.1 3 0 0 3 3 3 1 FANCL C-terminal domain RINGv PF12906.7 KSA00487.1 - 0.0032 17.6 0.4 0.013 15.6 0.4 2.1 1 0 0 1 1 1 1 RING-variant domain PHD_4 PF16866.5 KSA00487.1 - 0.051 13.7 1.2 0.098 12.8 0.1 2.0 2 0 0 2 2 2 0 PHD-finger TPR_1 PF00515.28 KSA00488.1 - 3.8e-52 172.1 26.2 1.7e-07 30.7 0.0 11.2 11 1 0 11 11 11 8 Tetratricopeptide repeat TPR_2 PF07719.17 KSA00488.1 - 3.2e-50 164.2 22.2 3.4e-06 26.8 0.0 10.5 11 0 0 11 11 10 9 Tetratricopeptide repeat TPR_17 PF13431.6 KSA00488.1 - 5.9e-36 120.3 10.9 0.00041 20.5 0.2 10.2 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_8 PF13181.6 KSA00488.1 - 1.5e-35 118.4 13.8 0.00018 21.4 0.0 11.2 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_11 PF13414.6 KSA00488.1 - 2.2e-33 113.7 23.8 2.7e-06 26.9 0.0 9.7 4 2 5 9 9 9 8 TPR repeat TPR_14 PF13428.6 KSA00488.1 - 1.8e-30 103.0 7.2 5.2e-05 23.7 0.0 9.2 4 2 5 9 9 9 5 Tetratricopeptide repeat TPR_16 PF13432.6 KSA00488.1 - 4e-26 91.4 11.2 4.1e-05 24.1 0.3 6.6 5 2 0 6 6 6 6 Tetratricopeptide repeat TPR_19 PF14559.6 KSA00488.1 - 3.6e-24 85.0 10.7 0.00042 20.8 0.3 6.8 6 1 0 6 6 6 6 Tetratricopeptide repeat TPR_12 PF13424.6 KSA00488.1 - 2.9e-23 81.9 18.1 0.00019 21.6 0.3 8.4 4 2 4 8 8 8 8 Tetratricopeptide repeat TPR_9 PF13371.6 KSA00488.1 - 3.7e-22 78.3 9.4 0.0019 18.3 0.1 6.6 2 2 4 7 7 7 7 Tetratricopeptide repeat TPR_7 PF13176.6 KSA00488.1 - 3.7e-21 73.6 7.9 0.017 15.1 0.0 9.4 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_6 PF13174.6 KSA00488.1 - 2.8e-20 71.5 6.9 0.0093 16.6 0.0 9.1 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_15 PF13429.6 KSA00488.1 - 9.4e-13 48.0 2.1 0.0019 17.5 0.2 5.4 2 2 3 5 5 5 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KSA00488.1 - 2e-11 44.0 6.4 2.6e-05 24.4 0.4 3.8 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 KSA00488.1 - 2.3e-09 37.1 0.2 0.015 14.7 0.0 4.1 3 1 2 5 5 5 3 MalT-like TPR region TPR_10 PF13374.6 KSA00488.1 - 5.6e-06 26.1 16.8 0.72 9.8 0.0 8.3 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_21 PF09976.9 KSA00488.1 - 0.001 18.9 7.0 2.9 7.6 0.0 4.9 5 1 0 5 5 5 2 Tetratricopeptide repeat-like domain ChAPs PF09295.10 KSA00488.1 - 0.0013 17.8 0.1 0.085 11.8 0.0 2.9 2 1 0 3 3 3 1 ChAPs (Chs5p-Arf1p-binding proteins) Cohesin_load PF10345.9 KSA00488.1 - 0.06 11.8 0.1 2.5 6.4 0.1 2.7 3 0 0 3 3 3 0 Cohesin loading factor TPR_20 PF14561.6 KSA00488.1 - 0.11 12.8 0.1 15 6.0 0.0 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat CDC27 PF09507.10 KSA00488.1 - 0.51 9.7 29.5 1 8.6 29.5 1.6 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 BTAD PF03704.17 KSA00488.1 - 0.59 10.5 6.0 11 6.5 0.2 3.1 2 2 2 4 4 4 0 Bacterial transcriptional activator domain NARP1 PF12569.8 KSA00488.1 - 1.7 7.4 0.0 1.7 7.4 0.0 5.3 4 2 2 6 6 5 0 NMDA receptor-regulated protein 1 DUF4769 PF15992.5 KSA00488.1 - 3.2 7.5 6.1 5.8 6.6 6.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4769) TPR_3 PF07720.12 KSA00488.1 - 7.2 6.7 14.4 74 3.5 0.0 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat NAD_kinase PF01513.21 KSA00489.1 - 1.4e-54 185.3 0.1 2e-54 184.8 0.1 1.2 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 KSA00489.1 - 0.00069 19.2 0.0 0.0015 18.1 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Hist_deacetyl PF00850.19 KSA00490.1 - 2.4e-79 267.0 0.0 3.8e-79 266.4 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain TMEM237 PF15383.6 KSA00490.1 - 0.57 9.2 3.0 0.94 8.5 3.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 237 SDA1 PF05285.12 KSA00490.1 - 0.79 9.1 20.6 1 8.7 20.6 1.1 1 0 0 1 1 1 0 SDA1 DHHC PF01529.20 KSA00491.1 - 4.3e-38 130.4 13.7 4.3e-38 130.4 13.7 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase UAA PF08449.11 KSA00492.1 - 1.3e-41 142.8 17.4 1.6e-41 142.5 17.4 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 KSA00492.1 - 0.024 14.8 29.1 0.067 13.4 11.3 3.8 3 1 1 4 4 4 0 EamA-like transporter family SRP68 PF16969.5 KSA00493.1 - 2.5e-64 218.2 11.3 3.2e-64 217.9 11.3 1.1 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 Utp12 PF04003.12 KSA00494.1 - 4.1e-10 39.9 0.0 7.5e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 KSA00494.1 - 0.00054 20.2 0.3 0.067 13.5 0.0 3.6 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain TBK1_ULD PF18396.1 KSA00494.1 - 0.0096 15.8 0.4 0.045 13.7 0.1 2.3 2 0 0 2 2 2 1 TANK binding kinase 1 ubiquitin-like domain vATP-synt_AC39 PF01992.16 KSA00494.1 - 0.023 14.2 0.4 0.038 13.5 0.4 1.2 1 0 0 1 1 1 0 ATP synthase (C/AC39) subunit TMF_TATA_bd PF12325.8 KSA00495.1 - 4.3e-34 117.2 18.8 4.3e-34 117.2 18.8 7.5 4 2 1 6 6 6 3 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 KSA00495.1 - 5.2e-17 61.6 20.1 5.2e-17 61.6 20.1 10.0 5 4 5 10 10 10 3 TATA element modulatory factor 1 DNA binding Spc7 PF08317.11 KSA00495.1 - 0.0023 16.9 8.2 0.0023 16.9 8.2 4.9 3 1 1 5 5 5 2 Spc7 kinetochore protein HIP1_clath_bdg PF16515.5 KSA00495.1 - 0.0051 17.4 11.6 0.0051 17.4 11.6 7.8 4 2 3 8 8 8 1 Clathrin-binding domain of Huntingtin-interacting protein 1 Fez1 PF06818.15 KSA00495.1 - 0.014 15.8 18.4 0.014 15.8 18.4 6.2 2 1 1 5 5 5 0 Fez1 OmpH PF03938.14 KSA00495.1 - 0.016 15.5 20.2 0.016 15.5 20.2 6.3 3 1 4 7 7 7 0 Outer membrane protein (OmpH-like) rve_3 PF13683.6 KSA00495.1 - 0.056 13.2 0.4 0.52 10.1 0.3 2.8 1 1 0 1 1 1 0 Integrase core domain DUF948 PF06103.11 KSA00495.1 - 1.4 9.2 38.3 0.4 11.0 1.3 6.4 5 2 3 8 8 8 0 Bacterial protein of unknown function (DUF948) FUSC PF04632.12 KSA00495.1 - 7.9 4.9 6.7 14 4.1 0.5 2.8 3 0 0 3 3 3 0 Fusaric acid resistance protein family Pox_MCEL PF03291.16 KSA00496.1 - 7.4e-105 350.7 0.0 1.1e-104 350.2 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 KSA00496.1 - 5.3e-08 33.5 0.0 1.9e-05 25.3 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KSA00496.1 - 3.2e-06 27.8 0.2 3.6e-05 24.4 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KSA00496.1 - 0.00014 21.7 0.0 0.00029 20.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KSA00496.1 - 0.00034 21.2 0.0 0.52 11.0 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 KSA00496.1 - 0.00037 20.4 0.0 0.00071 19.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Vel1p PF10339.9 KSA00496.1 - 0.017 14.5 0.0 0.034 13.5 0.0 1.4 1 0 0 1 1 1 0 Yeast-specific zinc responsive NNMT_PNMT_TEMT PF01234.17 KSA00496.1 - 0.029 13.5 0.0 0.054 12.7 0.0 1.3 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family FSH1 PF03959.13 KSA00497.1 - 5.8e-67 225.5 0.0 6.5e-67 225.3 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 KSA00497.1 - 0.0084 15.9 0.0 0.088 12.6 0.0 2.1 1 1 1 2 2 2 1 Phospholipase/Carboxylesterase Rit1_C PF17184.4 KSA00498.1 - 1.2e-85 287.3 0.1 1.9e-85 286.6 0.1 1.3 1 0 0 1 1 1 1 Rit1 N-terminal domain Init_tRNA_PT PF04179.12 KSA00498.1 - 9.7e-27 93.5 0.8 9.7e-27 93.5 0.8 1.9 2 0 0 2 2 2 1 Rit1 DUSP-like domain Cytokin_check_N PF10407.9 KSA00498.1 - 0.27 11.2 3.4 7.6 6.6 0.1 3.0 2 0 0 2 2 2 0 Cdc14 phosphatase binding protein N-terminus SPT2 PF08243.11 KSA00499.1 - 2.1e-28 99.1 16.9 2.1e-28 99.1 16.9 2.7 4 0 0 4 4 4 1 SPT2 chromatin protein Lyase_1 PF00206.20 KSA00500.1 - 1.8e-118 395.5 0.0 2.3e-118 395.1 0.0 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 KSA00500.1 - 1.9e-24 85.8 0.0 4.7e-24 84.6 0.0 1.7 1 0 0 1 1 1 1 Fumarase C C-terminus RAWUL PF16207.5 KSA00501.1 - 0.68 10.6 3.4 1.1 10.0 0.4 2.9 3 0 0 3 3 3 0 RAWUL domain RING finger- and WD40-associated ubiquitin-like Rad4 PF03835.15 KSA00502.1 - 1.2e-32 112.6 3.3 4.4e-32 110.8 3.3 2.0 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 KSA00502.1 - 4.9e-19 68.5 0.0 9.1e-19 67.6 0.0 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 KSA00502.1 - 6e-18 64.4 0.1 1.7e-17 63.0 0.1 1.8 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 KSA00502.1 - 2.5e-14 54.0 0.4 1e-13 52.0 0.4 2.2 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 KSA00502.1 - 0.059 13.8 0.0 0.16 12.4 0.0 1.7 1 1 0 1 1 1 0 Transglutaminase-like superfamily DUF4834 PF16118.5 KSA00503.1 - 0.0066 17.4 0.2 0.0085 17.0 0.1 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4834) Presenilin PF01080.17 KSA00503.1 - 0.056 12.2 0.1 0.062 12.1 0.1 1.2 1 0 0 1 1 1 0 Presenilin DUF4407 PF14362.6 KSA00503.1 - 0.1 11.9 0.2 0.11 11.9 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SID-1_RNA_chan PF13965.6 KSA00503.1 - 0.27 9.6 0.0 0.28 9.5 0.0 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Clc-like PF07062.12 KSA00504.1 - 0.013 15.0 0.0 0.03 13.8 0.0 1.5 1 0 0 1 1 1 0 Clc-like Tissue_fac PF01108.17 KSA00504.1 - 0.11 12.3 0.1 0.29 11.0 0.1 1.6 1 0 0 1 1 1 0 Tissue factor Translin PF01997.16 KSA00505.1 - 5.8e-12 46.0 0.4 8e-12 45.6 0.4 1.3 1 0 0 1 1 1 1 Translin family DUF4022 PF13214.6 KSA00505.1 - 0.0096 16.2 1.0 1.1 9.6 0.4 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF4022) DUF4743 PF15916.5 KSA00507.1 - 8.6e-10 38.6 0.0 1.5e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) NUDIX PF00293.28 KSA00507.1 - 8.8e-09 35.5 0.0 1.4e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Hamartin PF04388.12 KSA00508.1 - 4.6e-08 32.2 4.2 4.6e-08 32.2 4.2 2.6 2 1 0 2 2 2 1 Hamartin protein Herpes_BLRF2 PF05812.12 KSA00508.1 - 4.9 7.3 9.2 1.9 8.6 5.2 2.3 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein PMT PF02366.18 KSA00509.1 - 8.4e-81 271.2 21.7 8.4e-81 271.2 21.7 1.8 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KSA00509.1 - 1e-60 204.8 6.6 1e-60 204.8 6.6 3.5 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KSA00509.1 - 1.3e-14 54.5 0.6 4e-14 52.9 0.4 1.8 1 1 1 2 2 2 1 MIR domain DHHA2 PF02833.14 KSA00510.1 - 3.7e-28 98.5 1.5 7.2e-28 97.6 1.5 1.5 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.20 KSA00510.1 - 5.1e-08 33.1 0.0 9.5e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 DHH family HECT_2 PF09814.9 KSA00511.1 - 3.5e-68 230.2 6.8 4.3e-68 229.9 6.8 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding DiS_P_DiS PF06750.13 KSA00511.1 - 0.33 11.1 1.5 0.95 9.6 0.1 2.1 2 0 0 2 2 2 0 Bacterial Peptidase A24 N-terminal domain NCD3G PF07562.14 KSA00511.1 - 5.6 7.0 6.2 10 6.2 0.9 2.6 2 0 0 2 2 2 0 Nine Cysteines Domain of family 3 GPCR TB2_DP1_HVA22 PF03134.19 KSA00512.1 - 0.016 15.1 1.3 0.035 14.0 1.3 1.6 1 0 0 1 1 1 0 TB2/DP1, HVA22 family Swi3 PF07962.12 KSA00513.1 - 1.7e-26 92.0 1.8 3.6e-26 91.0 1.8 1.5 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 BpuJI_N PF11564.8 KSA00513.1 - 0.017 14.4 0.2 0.027 13.7 0.2 1.2 1 0 0 1 1 1 0 Restriction endonuclease BpuJI - N terminal GNAT_C PF18164.1 KSA00513.1 - 0.029 14.1 0.3 1.1 8.9 0.1 2.3 2 0 0 2 2 2 0 GNAT-like C-terminal domain VWA_2 PF13519.6 KSA00514.1 - 5.7e-21 75.2 0.4 2.6e-20 73.1 0.0 2.1 3 0 0 3 3 3 1 von Willebrand factor type A domain VWA PF00092.28 KSA00514.1 - 7e-08 32.9 0.6 1.3e-07 32.0 0.6 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.14 KSA00514.1 - 3.1e-06 27.1 0.0 4.3e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like UIM PF02809.20 KSA00514.1 - 0.0058 16.5 0.3 0.017 15.0 0.3 1.8 1 0 0 1 1 1 1 Ubiquitin interaction motif OSK PF17182.4 KSA00514.1 - 0.018 14.3 0.1 0.031 13.5 0.1 1.3 1 0 0 1 1 1 0 OSK domain Sec23_trunk PF04811.15 KSA00514.1 - 0.12 11.9 0.1 0.56 9.7 0.1 1.9 1 1 1 2 2 2 0 Sec23/Sec24 trunk domain Nbl1_Borealin_N PF10444.9 KSA00515.1 - 0.00019 21.0 0.6 0.00033 20.2 0.6 1.4 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal NIR_SIR PF01077.22 KSA00516.1 - 5.8e-51 172.1 0.0 8.7e-48 161.8 0.0 2.4 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 KSA00516.1 - 1.6e-28 98.3 0.0 6.9e-14 51.5 0.0 2.9 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.25 KSA00516.1 - 1.4e-26 93.5 0.1 1.4e-25 90.1 0.0 2.5 2 0 0 2 2 2 1 Flavodoxin Flavodoxin_3 PF12641.7 KSA00516.1 - 0.052 13.3 0.6 0.21 11.3 0.0 2.3 3 0 0 3 3 3 0 Flavodoxin domain POR_N PF01855.19 KSA00516.1 - 0.096 12.4 0.0 0.5 10.1 0.0 2.0 2 0 0 2 2 2 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Xol-1_N PF09108.10 KSA00516.1 - 0.1 12.5 0.0 14 5.5 0.0 2.8 2 0 0 2 2 2 0 Switch protein XOL-1, N-terminal RelB_N PF18506.1 KSA00516.1 - 0.11 12.4 0.1 0.3 10.9 0.1 1.7 1 0 0 1 1 1 0 RelB Antitoxin alpha helical domain NIF3 PF01784.18 KSA00517.1 - 2.3e-78 263.2 0.0 2.7e-78 263.0 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) Kelch_4 PF13418.6 KSA00518.1 - 1.7e-16 60.0 2.0 3e-05 23.9 0.0 4.6 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_6 PF13964.6 KSA00518.1 - 1.5e-11 44.1 6.3 3.5e-06 27.1 0.3 4.7 5 0 0 5 5 5 2 Kelch motif Kelch_5 PF13854.6 KSA00518.1 - 3.2e-11 43.0 4.1 0.00036 20.4 0.4 4.5 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.25 KSA00518.1 - 3.3e-09 36.2 8.1 0.00015 21.3 0.4 3.9 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.15 KSA00518.1 - 3.7e-08 33.0 4.0 0.026 14.5 0.6 4.5 4 0 0 4 4 4 2 Kelch motif BTB PF00651.31 KSA00518.1 - 3.3e-05 24.1 0.0 7.4e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Kelch_3 PF13415.6 KSA00518.1 - 6.1e-05 23.2 4.7 0.16 12.3 0.1 3.6 4 0 0 4 4 4 2 Galactose oxidase, central domain Phosphodiest PF01663.22 KSA00519.1 - 1.4e-87 294.7 0.8 1.4e-87 294.7 0.8 1.4 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase MT0933_antitox PF14013.6 KSA00519.1 - 0.24 11.7 1.6 0.48 10.8 1.6 1.4 1 0 0 1 1 1 0 MT0933-like antitoxin protein zf-Nse PF11789.8 KSA00520.1 - 8.5e-19 67.1 0.0 1.5e-18 66.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_2 PF13923.6 KSA00520.1 - 0.00041 20.1 0.0 0.00075 19.3 0.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KSA00520.1 - 0.00058 19.8 0.1 0.0011 18.9 0.1 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 KSA00520.1 - 0.0031 17.8 0.1 0.0053 17.1 0.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KSA00520.1 - 0.0034 17.6 0.0 0.0065 16.7 0.0 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain ELFV_dehydrog PF00208.21 KSA00521.1 - 2.4e-86 289.4 4.4 3e-86 289.1 4.4 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 KSA00521.1 - 2.4e-50 169.7 0.0 5.6e-50 168.6 0.0 1.6 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain GATase_4 PF13230.6 KSA00521.1 - 0.06 12.2 0.0 10 4.9 0.0 2.2 2 0 0 2 2 2 0 Glutamine amidotransferases class-II NAD_binding_7 PF13241.6 KSA00521.1 - 0.092 13.2 0.4 0.21 12.0 0.4 1.8 1 1 0 1 1 1 0 Putative NAD(P)-binding Tim54 PF11711.8 KSA00522.1 - 3.7e-129 430.8 3.1 4.7e-129 430.4 3.1 1.1 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Phage_CI_repr PF07022.13 KSA00522.1 - 0.12 12.5 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage CI repressor helix-turn-helix domain cobW PF02492.19 KSA00523.1 - 5.2e-42 143.4 2.0 1.2e-41 142.2 1.5 1.7 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 KSA00523.1 - 2.3e-06 27.4 0.0 4.8e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain AAA_23 PF13476.6 KSA00523.1 - 2.7e-05 24.7 0.8 0.0063 17.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KSA00523.1 - 0.005 17.2 0.1 0.012 16.0 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 KSA00523.1 - 0.0054 16.7 1.1 1.3 9.0 0.0 2.6 3 0 0 3 3 3 2 RsgA GTPase AAA_29 PF13555.6 KSA00523.1 - 0.0054 16.4 0.5 0.016 15.0 0.1 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.6 KSA00523.1 - 0.027 15.0 0.0 0.1 13.1 0.0 2.1 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KSA00523.1 - 0.053 13.6 0.0 0.19 11.8 0.0 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase RPAP1_N PF08621.10 KSA00523.1 - 0.054 13.3 0.5 0.15 11.9 0.5 1.7 1 0 0 1 1 1 0 RPAP1-like, N-terminal AAA_14 PF13173.6 KSA00523.1 - 0.069 13.2 0.0 0.28 11.2 0.0 2.1 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KSA00523.1 - 0.086 12.7 0.1 0.086 12.7 0.1 2.2 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea DUF5371 PF17341.2 KSA00523.1 - 0.11 12.7 0.5 0.29 11.4 0.5 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5371) HMG_CoA_synt_N PF01154.17 KSA00523.1 - 0.18 11.6 3.4 0.28 11.0 0.1 2.5 3 0 0 3 3 3 0 Hydroxymethylglutaryl-coenzyme A synthase N terminal ABC_tran PF00005.27 KSA00523.1 - 0.62 10.6 5.9 2.6 8.6 5.7 2.4 1 1 0 1 1 1 0 ABC transporter DUF1542 PF07564.11 KSA00523.1 - 0.72 10.0 8.8 0.83 9.8 5.8 2.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) Glyco_transf_22 PF03901.17 KSA00524.1 - 2.6e-34 119.2 20.6 4.6e-34 118.3 20.6 1.3 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF1129 PF06570.11 KSA00524.1 - 0.0014 18.2 3.3 0.0014 18.2 3.3 2.8 2 1 1 3 3 3 1 Protein of unknown function (DUF1129) Sfi1 PF08457.10 KSA00525.1 - 1.4e-12 47.0 46.9 8e-10 37.9 30.8 3.9 2 2 0 2 2 2 2 Sfi1 spindle body protein Pkinase PF00069.25 KSA00526.1 - 8e-64 215.5 0.0 1.6e-63 214.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KSA00526.1 - 1e-41 143.0 0.0 1.7e-41 142.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KSA00526.1 - 9.5e-11 41.5 0.0 2.2e-07 30.5 0.0 2.4 2 0 0 2 2 2 2 Kinase-like A_deaminase_N PF08451.11 KSA00526.1 - 0.0049 17.1 0.1 0.025 14.9 0.1 2.2 2 0 0 2 2 2 1 Adenosine/AMP deaminase N-terminal Ribosomal_L21p PF00829.21 KSA00527.1 - 2.1e-10 40.8 0.0 2.6e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein UPF0640 PF15114.6 KSA00527.1 - 0.12 12.2 0.2 0.91 9.4 0.3 2.0 2 0 0 2 2 2 0 Uncharacterised protein family UPF0640 SAPS PF04499.15 KSA00528.1 - 2.2e-189 630.3 9.0 2.2e-189 630.3 9.0 3.2 3 0 0 3 3 3 2 SIT4 phosphatase-associated protein Spore_coat_CotO PF14153.6 KSA00528.1 - 0.00016 21.7 1.8 0.00016 21.7 1.8 2.8 3 1 0 3 3 3 1 Spore coat protein CotO Hid1 PF12722.7 KSA00528.1 - 0.0012 17.2 11.4 0.0012 17.2 11.4 2.7 3 0 0 3 3 3 1 High-temperature-induced dauer-formation protein GATase_4 PF13230.6 KSA00529.1 - 1.9e-12 46.7 0.1 4.3e-12 45.5 0.1 1.6 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.6 KSA00529.1 - 8.5e-10 39.0 0.0 1.5e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF1687 PF07955.11 KSA00530.1 - 1.6e-36 125.6 0.1 1.9e-36 125.4 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) PTPLA PF04387.14 KSA00531.1 - 2.2e-42 144.6 10.4 3.6e-42 143.9 10.4 1.3 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA PTPLA PF04387.14 KSA00532.1 - 1.4e-54 184.3 12.1 2.2e-54 183.6 12.1 1.3 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA ChAPs PF09295.10 KSA00533.1 - 3.1e-28 98.9 3.0 1.1e-23 83.9 2.0 2.5 2 0 0 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_1 PF00515.28 KSA00533.1 - 0.029 14.2 0.8 0.099 12.5 0.2 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 KSA00533.1 - 0.046 14.1 0.1 0.16 12.4 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat Ribosomal_L27A PF00828.19 KSA00533.1 - 0.11 13.2 0.4 1 10.1 0.1 2.4 2 0 0 2 2 2 0 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A LRR_8 PF13855.6 KSA00534.1 - 4.7e-45 151.2 74.4 6.1e-10 38.7 5.2 9.9 3 2 7 11 11 11 9 Leucine rich repeat PP2C PF00481.21 KSA00534.1 - 3.5e-42 144.8 0.0 8.3e-42 143.6 0.0 1.7 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.7 KSA00534.1 - 5.2e-31 106.2 93.9 1.5e-05 25.2 2.0 12.7 9 2 1 12 12 12 10 Leucine Rich repeats (2 copies) Guanylate_cyc PF00211.20 KSA00534.1 - 1.7e-26 93.0 0.0 4.9e-26 91.5 0.0 1.7 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_1 PF00560.33 KSA00534.1 - 1.4e-05 25.0 61.9 4.9 8.1 0.0 17.8 16 2 1 17 17 17 3 Leucine Rich Repeat LRR_9 PF14580.6 KSA00534.1 - 3.4e-05 23.4 32.5 0.0023 17.5 1.2 6.1 3 2 5 8 8 8 4 Leucine-rich repeat Ad_cyc_g-alpha PF08509.11 KSA00534.1 - 0.0089 15.7 0.9 0.024 14.3 0.9 1.7 1 0 0 1 1 1 1 Adenylate cyclase G-alpha binding domain PH_12 PF16457.5 KSA00535.1 - 4.7e-30 104.9 0.3 4.7e-30 104.9 0.3 1.7 2 0 0 2 2 2 1 Pleckstrin homology domain Fes1 PF08609.10 KSA00535.1 - 0.068 14.1 0.3 0.27 12.1 0.1 2.2 2 0 0 2 2 2 0 Nucleotide exchange factor Fes1 DUF1843 PF08898.10 KSA00535.1 - 0.13 12.8 0.1 1.2 9.6 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) DEAD PF00270.29 KSA00536.1 - 6.2e-45 153.1 0.0 1.4e-44 152.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KSA00536.1 - 3.3e-27 95.0 0.1 3.3e-27 95.0 0.1 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain N6_N4_Mtase PF01555.18 KSA00536.1 - 0.0002 21.2 0.0 16 5.1 8.8 2.8 2 1 0 2 2 2 1 DNA methylase NAD_Gly3P_dh_C PF07479.14 KSA00536.1 - 0.048 14.0 0.2 0.13 12.6 0.1 1.7 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus AAA_22 PF13401.6 KSA00536.1 - 0.11 12.8 0.3 0.48 10.7 0.3 2.2 1 1 0 1 1 1 0 AAA domain SYS1 PF09801.9 KSA00537.1 - 1.5e-31 109.4 13.6 1.8e-31 109.2 13.6 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network Y_phosphatase3 PF13350.6 KSA00538.1 - 1.1e-44 153.2 0.0 1.2e-44 153.0 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 KSA00538.1 - 0.00029 20.6 0.1 0.0023 17.8 0.1 2.1 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase2 PF03162.13 KSA00538.1 - 0.0013 18.4 0.0 0.0023 17.5 0.0 1.5 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 KSA00538.1 - 0.0041 16.7 0.0 0.0054 16.3 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KSA00538.1 - 0.0046 17.1 0.1 0.0081 16.3 0.1 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate cNMP_binding PF00027.29 KSA00539.1 - 1.5e-41 140.4 0.1 5.9e-20 71.1 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.17 KSA00539.1 - 3.7e-09 36.1 0.3 8.6e-09 34.9 0.3 1.7 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit SOBP PF15279.6 KSA00539.1 - 0.062 13.9 1.2 0.096 13.3 1.2 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Cupin_3 PF05899.12 KSA00539.1 - 0.2 11.4 1.0 2 8.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF861) Cupin_2 PF07883.11 KSA00539.1 - 4.8 7.0 9.0 2.1 8.1 0.0 2.6 3 0 0 3 3 3 0 Cupin domain Erg28 PF03694.13 KSA00540.1 - 1.1e-44 151.3 0.6 1.4e-44 151.0 0.6 1.1 1 0 0 1 1 1 1 Erg28 like protein TauD PF02668.16 KSA00541.1 - 3e-32 112.5 0.0 9.1e-32 110.9 0.0 1.6 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CN_hydrolase PF00795.22 KSA00542.1 - 8.2e-42 143.3 0.0 1.1e-41 142.9 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 KSA00542.1 - 7.3e-25 87.5 0.0 1.7e-24 86.3 0.0 1.5 1 1 0 1 1 1 1 NAD synthase DUF4160 PF13711.6 KSA00542.1 - 0.13 12.6 0.0 24 5.3 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4160) Abhydrolase_6 PF12697.7 KSA00543.1 - 3.1e-13 50.8 0.0 4.5e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KSA00543.1 - 7.3e-13 48.7 0.1 1.3e-12 47.9 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KSA00543.1 - 1.4e-12 47.5 0.0 2.2e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 KSA00543.1 - 0.022 13.7 0.0 0.04 12.8 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme PGAP1 PF07819.13 KSA00543.1 - 0.024 14.4 0.0 0.041 13.6 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Thioesterase PF00975.20 KSA00543.1 - 0.034 14.3 0.2 0.071 13.2 0.2 1.5 1 1 0 1 1 1 0 Thioesterase domain Lipase_3 PF01764.25 KSA00543.1 - 0.058 13.2 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_5 PF12695.7 KSA00543.1 - 0.17 11.7 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family dCMP_cyt_deam_1 PF00383.23 KSA00544.1 - 8.4e-19 67.3 0.1 1.2e-18 66.9 0.1 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KSA00544.1 - 8.9e-13 48.2 0.1 3.9e-12 46.1 0.1 1.9 1 1 0 1 1 1 1 MafB19-like deaminase Inv-AAD PF18785.1 KSA00544.1 - 1.2e-06 28.4 0.0 2.3e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase SNAD4 PF18750.1 KSA00544.1 - 0.0024 18.0 0.0 0.0044 17.1 0.0 1.4 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC_N PF08210.11 KSA00544.1 - 0.0065 16.4 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 APOBEC-like N-terminal domain NAD1 PF18778.1 KSA00544.1 - 0.008 16.3 0.0 0.017 15.3 0.0 1.5 1 0 0 1 1 1 1 Novel AID APOBEC clade 1 APOBEC3 PF18771.1 KSA00544.1 - 0.018 15.2 0.0 0.043 13.9 0.0 1.6 1 0 0 1 1 1 0 APOBEC3 Bd3614-deam PF14439.6 KSA00544.1 - 0.027 14.6 0.3 0.14 12.3 0.3 2.0 1 1 0 1 1 1 0 Bd3614-like deaminase APOBEC2 PF18772.1 KSA00544.1 - 0.04 14.0 0.0 0.067 13.2 0.0 1.3 1 0 0 1 1 1 0 APOBEC2 DUF1835 PF08874.10 KSA00544.1 - 0.14 12.4 0.2 0.63 10.3 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1835) Ssl1 PF04056.14 KSA00545.1 - 4.8e-62 209.2 0.1 7.2e-62 208.6 0.1 1.2 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.12 KSA00545.1 - 1.1e-25 89.6 18.5 1.6e-25 89.1 9.3 2.5 2 0 0 2 2 2 2 TFIIH C1-like domain VWA_2 PF13519.6 KSA00545.1 - 9.6e-14 51.9 0.0 2.8e-13 50.5 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain zinc_ribbon_15 PF17032.5 KSA00545.1 - 0.099 13.4 17.1 1.7 9.5 6.7 2.6 2 0 0 2 2 2 0 zinc-ribbon family IBR PF01485.21 KSA00545.1 - 0.96 9.7 17.7 0.71 10.1 9.4 2.8 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain DZR PF12773.7 KSA00545.1 - 8.8 6.4 17.9 6.8 6.8 4.1 2.9 1 1 1 2 2 2 0 Double zinc ribbon Spt5-NGN PF03439.13 KSA00546.1 - 5.2e-24 84.0 0.0 1.2e-23 82.8 0.0 1.7 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.8 KSA00546.1 - 1.9e-21 76.9 14.8 1.9e-21 76.9 14.8 3.7 2 1 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.29 KSA00546.1 - 1.2e-12 47.3 8.5 3e-06 27.0 0.3 5.1 5 0 0 5 5 5 3 KOW motif MCM_bind PF09739.9 KSA00546.1 - 0.18 10.2 0.0 0.18 10.2 0.0 2.6 2 1 1 3 3 3 0 Mini-chromosome maintenance replisome factor Pribosyltran PF00156.27 KSA00547.1 - 3.6e-14 52.6 0.0 4.9e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KSA00547.1 - 0.0095 15.4 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_3 PF15610.6 KSA00547.1 - 0.08 12.2 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 PRTase ComF-like Dynein_light PF01221.18 KSA00548.1 - 9.5e-34 115.6 0.0 1.1e-33 115.4 0.0 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Gp-FAR-1 PF05823.12 KSA00548.1 - 0.055 13.8 0.0 0.071 13.5 0.0 1.1 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF3646 PF12362.8 KSA00548.1 - 0.15 12.4 0.0 0.32 11.3 0.0 1.4 1 1 0 1 1 1 0 DNA polymerase III gamma and tau subunits C terminal Ectatomin PF06457.11 KSA00548.1 - 0.2 11.6 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 Ectatomin HD PF01966.22 KSA00549.1 - 9.3e-08 32.3 0.1 1.9e-07 31.3 0.1 1.5 1 1 0 1 1 1 1 HD domain Med13_N PF11597.8 KSA00550.1 - 1.6e-60 205.1 5.6 3.4e-60 204.1 5.6 1.5 1 0 0 1 1 1 1 Mediator complex subunit 13 N-terminal Med13_C PF06333.12 KSA00550.1 - 5.5e-16 58.8 1.8 5.5e-16 58.8 1.8 4.7 2 2 1 3 3 3 1 Mediator complex subunit 13 C-terminal domain MID_MedPIWI PF18296.1 KSA00550.1 - 0.002 18.0 0.7 0.01 15.6 0.2 5.2 5 2 1 6 6 6 2 MID domain of medPIWI MPS2 PF17060.5 KSA00551.1 - 0.027 13.8 6.3 0.05 12.9 6.3 1.5 1 0 0 1 1 1 0 Monopolar spindle protein 2 Fzo_mitofusin PF04799.13 KSA00551.1 - 0.057 13.0 3.4 0.15 11.6 3.4 1.6 1 0 0 1 1 1 0 fzo-like conserved region Spc42p PF11544.8 KSA00551.1 - 7.6 6.6 15.3 0.51 10.4 1.3 3.0 1 1 1 2 2 2 0 Spindle pole body component Spc42p TMF_TATA_bd PF12325.8 KSA00551.1 - 8 6.7 19.2 1.9 8.7 9.9 2.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Cyclin_N PF00134.23 KSA00552.1 - 1.7e-44 150.6 0.2 1.1e-43 148.1 0.2 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KSA00552.1 - 2.5e-31 108.2 0.0 9.9e-31 106.3 0.0 2.1 2 0 0 2 2 2 1 Cyclin, C-terminal domain BRCT PF00533.26 KSA00553.1 - 8.4e-29 99.8 4.5 5.3e-09 36.3 0.1 4.7 4 1 0 4 4 4 4 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KSA00553.1 - 3.3e-26 91.0 0.4 7.1e-15 54.7 0.1 4.8 4 1 0 4 4 4 3 twin BRCT domain BRCT_2 PF16589.5 KSA00553.1 - 1.7e-23 82.8 2.0 2e-05 24.9 0.0 4.4 4 0 0 4 4 4 4 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 KSA00553.1 - 0.00075 19.7 0.8 0.019 15.2 0.0 3.2 3 0 0 3 3 3 1 DNA ligase 3 BRCT domain RTT107_BRCT_5 PF16770.5 KSA00553.1 - 0.0096 15.8 0.1 0.35 10.8 0.0 3.2 3 0 0 3 3 3 1 Regulator of Ty1 transposition protein 107 BRCT domain SURF2 PF05477.11 KSA00553.1 - 0.042 13.5 4.6 0.069 12.8 4.6 1.4 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) DUF4746 PF15928.5 KSA00553.1 - 0.072 12.5 7.5 0.13 11.6 7.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) RTT107_BRCT_5 PF16770.5 KSA00554.1 - 2.7e-27 94.6 1.9 3.5e-26 91.0 0.4 2.4 2 0 0 2 2 2 1 Regulator of Ty1 transposition protein 107 BRCT domain RTT107_BRCT_6 PF16771.5 KSA00554.1 - 2e-19 69.9 2.5 2e-19 69.9 2.5 2.2 2 0 0 2 2 2 1 Regulator of Ty1 transposition protein 107 BRCT domain ENTH PF01417.20 KSA00555.1 - 5.2e-43 146.1 0.0 1e-42 145.1 0.0 1.5 1 0 0 1 1 1 1 ENTH domain UIM PF02809.20 KSA00555.1 - 2.3e-05 24.0 9.1 0.0039 17.0 1.2 2.9 2 0 0 2 2 2 2 Ubiquitin interaction motif zf-piccolo PF05715.13 KSA00556.1 - 0.13 12.4 9.7 0.47 10.6 2.4 2.6 2 0 0 2 2 2 0 Piccolo Zn-finger TFIIA PF03153.13 KSA00556.1 - 0.3 11.0 35.1 0.34 10.9 20.1 2.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DZR PF12773.7 KSA00556.1 - 7.1 6.7 7.5 9 6.4 0.5 2.6 2 0 0 2 2 2 0 Double zinc ribbon Glyco_hydro_76 PF03663.14 KSA00557.1 - 1.2e-155 518.6 23.2 1.4e-155 518.4 23.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 PX PF00787.24 KSA00558.1 - 2.9e-13 49.8 5.9 3.9e-13 49.4 0.8 3.0 2 1 0 2 2 2 1 PX domain DUF2400 PF09674.10 KSA00558.1 - 0.18 11.8 2.6 0.29 11.1 1.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2400) DUF1664 PF07889.12 KSA00558.1 - 0.25 11.4 2.9 16 5.5 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) SAS-6_N PF16531.5 KSA00558.1 - 0.29 11.7 7.1 39 4.9 7.1 2.7 1 1 0 1 1 1 0 Centriolar protein SAS N-terminal Lung_7-TM_R PF06814.13 KSA00559.1 - 1.7e-54 185.1 18.0 2.8e-54 184.4 18.0 1.3 1 0 0 1 1 1 1 Lung seven transmembrane receptor PCI PF01399.27 KSA00560.1 - 4.1e-10 40.1 0.2 4.1e-10 40.1 0.2 2.8 3 0 0 3 3 3 1 PCI domain Rpn9_C PF18261.1 KSA00560.1 - 0.019 14.5 0.0 0.038 13.6 0.0 1.5 1 0 0 1 1 1 0 Rpn9 C-terminal helix Csm1_B PF18211.1 KSA00560.1 - 0.029 14.2 0.3 0.029 14.2 0.3 3.2 3 1 0 4 4 4 0 Csm1 subunit domain B Leuk-A4-hydro_C PF09127.11 KSA00560.1 - 0.95 9.6 6.4 0.97 9.5 0.5 3.3 3 1 0 3 3 3 0 Leukotriene A4 hydrolase, C-terminal TFIIIC_delta PF12657.7 KSA00561.1 - 3.3e-27 95.6 2.3 1.8e-25 89.9 0.1 3.4 3 0 0 3 3 3 1 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.7 KSA00561.1 - 1.6e-06 28.0 0.0 6.2e-06 26.1 0.0 2.0 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex AAA_12 PF13087.6 KSA00562.1 - 1.3e-57 194.6 0.0 4.2e-57 193.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KSA00562.1 - 8.6e-35 120.8 1.6 5.2e-18 65.8 0.1 4.4 2 2 1 3 3 2 2 AAA domain AAA_19 PF13245.6 KSA00562.1 - 3.1e-11 43.8 0.3 1.1e-10 42.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KSA00562.1 - 1.3e-09 38.1 0.0 5.4e-09 36.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 KSA00562.1 - 1.5e-05 25.1 0.0 1.5e-05 25.1 0.0 4.3 3 2 0 3 3 2 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 KSA00562.1 - 1.7e-05 24.7 2.0 0.29 10.9 0.0 4.2 4 0 0 4 4 4 2 Viral (Superfamily 1) RNA helicase DEAD PF00270.29 KSA00562.1 - 0.00084 19.1 0.8 0.025 14.4 0.8 2.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase PhoH PF02562.16 KSA00562.1 - 0.01 15.3 0.1 0.099 12.1 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein UPF1_Zn_bind PF09416.10 KSA00562.1 - 0.016 15.2 6.6 0.042 13.8 1.0 3.2 2 1 1 3 3 3 0 RNA helicase (UPF2 interacting domain) AAA_22 PF13401.6 KSA00562.1 - 0.024 14.9 0.0 0.14 12.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KSA00562.1 - 0.031 14.7 3.1 0.35 11.3 0.2 3.5 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 KSA00562.1 - 0.077 12.0 0.1 0.17 11.0 0.1 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.6 KSA00562.1 - 0.15 12.4 0.0 0.3 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Hamartin PF04388.12 KSA00562.1 - 0.52 8.9 36.9 0.84 8.2 36.9 1.2 1 0 0 1 1 1 0 Hamartin protein Helicase_RecD PF05127.14 KSA00562.1 - 0.75 9.6 2.6 3.9 7.3 0.0 3.0 3 0 0 3 3 3 0 Helicase RasGEF PF00617.19 KSA00563.1 - 1.3e-43 149.2 3.3 1.3e-43 149.2 3.3 2.6 3 0 0 3 3 3 1 RasGEF domain RasGEF_N PF00618.20 KSA00563.1 - 1.2e-12 48.0 1.5 8.6e-12 45.2 1.5 2.6 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.28 KSA00563.1 - 0.00087 18.9 0.0 0.0024 17.5 0.0 1.8 1 0 0 1 1 1 1 SH3 domain Imm53 PF15580.6 KSA00563.1 - 0.025 14.3 0.7 0.76 9.5 0.0 3.4 3 0 0 3 3 3 0 Immunity protein 53 Aconitase PF00330.20 KSA00564.1 - 6.7e-151 503.4 0.0 2.2e-150 501.7 0.0 1.7 2 0 0 2 2 2 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KSA00564.1 - 1.5e-42 145.0 0.0 2.6e-42 144.2 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain ATP-synt_ab PF00006.25 KSA00565.1 - 7.7e-66 221.8 0.0 1.2e-65 221.1 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 KSA00565.1 - 1.1e-13 51.5 0.9 2.2e-13 50.5 0.9 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain ACP_PD PF04336.12 KSA00566.1 - 0.028 14.9 1.1 3.8 8.0 0.1 3.1 3 0 0 3 3 3 0 Acyl carrier protein phosphodiesterase Glyco_hydro_130 PF04041.13 KSA00567.1 - 1e-40 139.6 0.1 1.3e-40 139.3 0.1 1.1 1 0 0 1 1 1 1 beta-1,4-mannooligosaccharide phosphorylase Glyco_hydro_32N PF00251.20 KSA00567.1 - 1.4e-09 37.9 2.0 1.2e-07 31.7 0.0 2.6 3 0 0 3 3 3 2 Glycosyl hydrolases family 32 N-terminal domain PP2C PF00481.21 KSA00568.1 - 2.9e-55 187.7 0.0 3.9e-55 187.3 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KSA00568.1 - 0.00011 21.9 0.0 0.00016 21.4 0.0 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C SeleniumBinding PF11524.8 KSA00568.1 - 0.087 13.3 0.0 0.23 11.9 0.0 1.7 1 0 0 1 1 1 0 Selenium binding protein Glyco_transf_20 PF00982.21 KSA00570.1 - 1.5e-201 670.2 0.0 1.7e-201 670.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glycos_transf_1 PF00534.20 KSA00570.1 - 1.7e-05 24.4 0.5 0.0089 15.6 0.1 2.7 2 1 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 KSA00570.1 - 0.03 14.0 0.0 0.055 13.1 0.0 1.4 1 0 0 1 1 1 0 Starch synthase catalytic domain DUF4342 PF14242.6 KSA00570.1 - 0.19 11.7 0.8 0.51 10.4 0.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4342) YIF1 PF03878.15 KSA00571.1 - 3.7e-86 288.5 7.6 3.7e-86 288.5 7.6 1.4 2 0 0 2 2 2 1 YIF1 DUF1744 PF08490.12 KSA00572.1 - 2.5e-144 480.8 3.7 4.4e-144 480.0 3.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 KSA00572.1 - 3.8e-76 256.4 6.5 2.9e-75 253.5 2.6 2.7 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 KSA00572.1 - 1.9e-16 59.8 0.0 3e-14 52.6 0.0 3.1 3 1 0 3 3 3 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 KSA00572.1 - 1.7e-06 27.8 0.3 5.4e-06 26.2 0.3 1.8 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 KSA00572.1 - 9e-06 25.8 0.3 4.5e-05 23.5 0.1 2.3 2 0 0 2 2 2 1 RNase_H superfamily NAPRTase_C PF17956.1 KSA00572.1 - 0.02 15.3 0.1 0.18 12.3 0.0 2.6 2 0 0 2 2 2 0 Nicotinate phosphoribosyltransferase C-terminal domain Peptidase_M76 PF09768.9 KSA00572.1 - 0.026 14.3 3.6 0.053 13.3 3.0 1.8 2 0 0 2 2 2 0 Peptidase M76 family Ribosomal_L32p PF01783.23 KSA00572.1 - 7.6 6.9 6.8 23 5.3 0.0 3.2 3 0 0 3 3 3 0 Ribosomal L32p protein family ORC5_C PF14630.6 KSA00573.1 - 2.1e-73 247.3 0.7 2.7e-73 247.0 0.7 1.1 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.6 KSA00573.1 - 7.8e-10 39.4 0.0 1.5e-09 38.5 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KSA00573.1 - 0.0099 16.3 0.0 0.026 14.9 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KSA00573.1 - 0.092 13.0 0.2 0.31 11.3 0.2 1.9 1 1 0 1 1 1 0 AAA domain GYF PF02213.16 KSA00574.1 - 1.6e-12 46.9 3.0 4.6e-12 45.4 3.0 1.9 1 0 0 1 1 1 1 GYF domain Yae1_N PF09811.9 KSA00575.1 - 3.9e-12 45.7 9.3 6.8e-12 44.9 9.3 1.4 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Snapin_Pallidin PF14712.6 KSA00575.1 - 0.1 13.1 0.5 0.1 13.1 0.5 2.0 2 1 0 2 2 2 0 Snapin/Pallidin TFIID_20kDa PF03847.13 KSA00575.1 - 0.43 11.1 4.4 16 6.1 0.1 3.1 3 0 0 3 3 3 0 Transcription initiation factor TFIID subunit A Prion PF00377.18 KSA00575.1 - 0.81 9.6 5.0 0.1 12.4 0.3 1.7 2 0 0 2 2 2 0 Prion/Doppel alpha-helical domain WD40 PF00400.32 KSA00576.1 - 3.9e-07 30.7 5.1 0.0039 18.0 0.5 4.5 4 0 0 4 4 4 2 WD domain, G-beta repeat DUF2415 PF10313.9 KSA00576.1 - 0.05 13.5 0.0 0.71 9.9 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein domain (DUF2415) Colicin_im PF03857.13 KSA00576.1 - 0.13 12.3 0.0 0.21 11.6 0.0 1.2 1 0 0 1 1 1 0 Colicin immunity protein HMA PF00403.26 KSA00578.1 - 2e-11 44.2 0.5 2.4e-11 43.9 0.5 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain DUF836 PF05768.14 KSA00578.1 - 0.06 13.8 0.1 0.08 13.4 0.1 1.2 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) CTU2 PF10288.9 KSA00578.1 - 0.11 12.7 0.7 1.5 9.1 0.1 2.0 1 1 1 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 Spore_Cse60 PF10957.8 KSA00578.1 - 0.12 12.4 0.6 0.18 11.8 0.4 1.6 1 1 1 2 2 2 0 Sporulation protein Cse60 Dsl1_C PF11989.8 KSA00579.1 - 2.5e-17 63.2 17.1 2.5e-17 63.2 17.1 3.4 2 2 1 3 3 3 1 Retrograde transport protein Dsl1 C terminal UCH PF00443.29 KSA00579.1 - 0.0016 18.0 0.0 0.037 13.5 0.0 2.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Retrotran_gag_2 PF14223.6 KSA00579.1 - 0.0018 17.9 6.7 0.0073 16.0 0.5 3.7 4 0 0 4 4 4 1 gag-polypeptide of LTR copia-type RuvX PF03652.15 KSA00579.1 - 0.18 12.2 0.8 1.4 9.3 0.1 2.4 2 0 0 2 2 2 0 Holliday junction resolvase SDA1 PF05285.12 KSA00579.1 - 0.83 9.0 13.1 1.3 8.3 13.1 1.3 1 0 0 1 1 1 0 SDA1 DnaA_N PF11638.8 KSA00579.1 - 1.4 8.7 6.1 23 4.9 0.3 4.2 4 0 0 4 4 4 0 DnaA N-terminal domain PEX11 PF05648.14 KSA00580.1 - 0.00056 19.4 0.2 0.00056 19.4 0.2 1.8 2 0 0 2 2 2 1 Peroxisomal biogenesis factor 11 (PEX11) DUF948 PF06103.11 KSA00581.1 - 0.0039 17.4 2.1 0.0039 17.4 2.1 3.0 3 1 1 4 4 4 1 Bacterial protein of unknown function (DUF948) DUF1216 PF06746.11 KSA00581.1 - 0.0088 16.1 3.3 0.0088 16.1 3.3 2.6 2 1 1 3 3 3 2 Protein of unknown function (DUF1216) BRE1 PF08647.11 KSA00581.1 - 0.016 15.3 4.7 0.016 15.3 4.7 4.7 3 2 1 4 4 4 0 BRE1 E3 ubiquitin ligase HD_5 PF13487.6 KSA00581.1 - 0.024 14.9 5.2 0.23 11.7 0.1 3.3 2 1 1 3 3 3 0 HD domain DUF668 PF05003.12 KSA00581.1 - 0.048 14.1 5.0 1.4 9.4 0.3 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF668) DUF745 PF05335.13 KSA00581.1 - 0.1 12.3 14.8 0.66 9.7 2.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF745) DUF489 PF04356.12 KSA00581.1 - 2.2 8.2 14.3 0.55 10.2 7.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF489) SlyX PF04102.12 KSA00581.1 - 8 7.2 21.9 3.8 8.2 3.0 4.4 3 2 1 4 4 4 0 SlyX Hydrolase_6 PF13344.6 KSA00582.1 - 2.6e-19 69.2 0.0 5.8e-19 68.1 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KSA00582.1 - 2.5e-14 53.1 0.0 1.6e-13 50.5 0.0 2.4 2 1 0 2 2 2 1 HAD-hyrolase-like Como_LCP PF02247.16 KSA00582.1 - 0.15 10.7 0.0 0.22 10.1 0.0 1.2 1 0 0 1 1 1 0 Large coat protein Pkinase PF00069.25 KSA00583.1 - 8.3e-70 235.2 0.0 1.7e-69 234.1 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KSA00583.1 - 1.3e-47 162.3 0.0 2.5e-47 161.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 KSA00583.1 - 1.5e-20 73.3 0.0 6.7e-20 71.2 0.0 2.3 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.6 KSA00583.1 - 1.5e-05 24.5 0.0 3.1e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KSA00583.1 - 0.00078 18.3 2.6 0.00078 18.3 2.6 3.5 3 1 0 3 3 3 1 Fungal protein kinase APH PF01636.23 KSA00583.1 - 0.093 12.6 0.1 0.64 9.9 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family DSHCT PF08148.12 KSA00583.1 - 0.11 12.2 0.0 0.32 10.6 0.0 1.8 1 0 0 1 1 1 0 DSHCT (NUC185) domain Smr PF01713.21 KSA00584.1 - 4.8e-05 23.6 0.0 6.7e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Smr domain SNARE_assoc PF09335.11 KSA00585.1 - 1.4e-12 48.2 2.7 2.7e-12 47.2 2.7 1.5 1 0 0 1 1 1 1 SNARE associated Golgi protein DUF2953 PF11167.8 KSA00585.1 - 0.067 13.3 0.8 0.16 12.1 0.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2953) TctB PF07331.11 KSA00585.1 - 1.2 9.4 13.9 2.8 8.2 13.9 1.6 1 1 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family LIM PF00412.22 KSA00587.1 - 5.2e-12 45.8 32.3 2.1e-06 27.8 17.2 2.6 2 1 0 2 2 2 2 LIM domain Clathrin PF00637.20 KSA00589.1 - 1.1e-192 631.7 54.0 4.3e-33 114.2 3.1 8.5 9 0 0 9 9 9 7 Region in Clathrin and VPS Clathrin_H_link PF13838.6 KSA00589.1 - 2.5e-27 94.6 2.7 3.2e-27 94.2 0.6 2.3 2 0 0 2 2 2 1 Clathrin-H-link Clathrin_propel PF01394.20 KSA00589.1 - 2.3e-20 71.8 3.9 0.00041 20.5 0.1 6.7 6 0 0 6 6 6 5 Clathrin propeller repeat Clathrin-link PF09268.10 KSA00589.1 - 6.5e-08 31.8 0.1 2.1e-07 30.2 0.1 2.0 1 0 0 1 1 1 1 Clathrin, heavy-chain linker Vps39_1 PF10366.9 KSA00589.1 - 9.4e-05 22.7 7.2 0.082 13.2 0.1 6.0 5 0 0 5 5 5 2 Vacuolar sorting protein 39 domain 1 TPR_2 PF07719.17 KSA00589.1 - 0.00034 20.5 8.5 6.3 7.2 0.0 7.3 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_1 PF00515.28 KSA00589.1 - 0.031 14.1 11.2 14 5.7 0.0 6.5 7 0 0 7 7 7 0 Tetratricopeptide repeat Utp13 PF08625.11 KSA00589.1 - 0.053 13.4 1.1 0.32 10.9 0.1 3.0 3 0 0 3 3 3 0 Utp13 specific WD40 associated domain PQQ_2 PF13360.6 KSA00589.1 - 0.11 12.0 0.1 6.3 6.3 0.0 2.6 3 0 0 3 3 3 0 PQQ-like domain TPR_7 PF13176.6 KSA00589.1 - 0.14 12.3 1.0 88 3.5 0.0 5.6 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 KSA00589.1 - 0.47 11.0 1.5 64 4.2 0.0 5.1 7 0 0 7 7 6 0 Tetratricopeptide repeat PPR PF01535.20 KSA00589.1 - 1.3 9.4 6.9 15 6.1 0.1 5.4 5 0 0 5 5 4 0 PPR repeat CENP-O PF09496.10 KSA00590.1 - 4e-28 98.8 0.7 7.6e-28 97.9 0.1 1.7 2 0 0 2 2 2 1 Cenp-O kinetochore centromere component Filament PF00038.21 KSA00590.1 - 0.02 14.5 7.3 0.049 13.2 0.3 2.5 3 0 0 3 3 3 0 Intermediate filament protein APG6_N PF17675.1 KSA00590.1 - 0.077 13.5 0.9 0.077 13.5 0.9 2.6 4 0 0 4 4 4 0 Apg6 coiled-coil region PI3K_P85_iSH2 PF16454.5 KSA00590.1 - 2.2 7.9 9.3 16 5.0 0.3 3.6 2 1 0 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain HIP1_clath_bdg PF16515.5 KSA00590.1 - 4.7 7.9 7.5 3.3 8.4 0.1 3.1 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 RhoGAP PF00620.27 KSA00591.1 - 1.9e-05 24.5 0.0 0.00014 21.7 0.0 2.5 1 0 0 1 1 1 1 RhoGAP domain Phage_sheath_1C PF17482.2 KSA00591.1 - 0.34 10.9 5.3 2.8 7.9 0.4 3.8 3 1 0 3 3 3 0 Phage tail sheath C-terminal domain BAR PF03114.18 KSA00591.1 - 2.6 7.6 14.6 0.29 10.8 0.6 2.9 3 0 0 3 3 3 0 BAR domain CorA PF01544.18 KSA00592.1 - 0.00015 21.2 0.7 0.00015 21.2 0.7 2.3 1 1 1 2 2 2 2 CorA-like Mg2+ transporter protein Muted PF14942.6 KSA00592.1 - 0.12 12.8 8.1 0.11 12.8 2.9 2.4 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein DDE_Tnp_ISL3 PF01610.17 KSA00592.1 - 0.15 11.7 1.8 0.25 11.0 1.8 1.3 1 0 0 1 1 1 0 Transposase Osmo_CC PF08946.10 KSA00592.1 - 0.29 11.4 3.4 0.19 12.0 0.9 2.0 2 0 0 2 2 2 0 Osmosensory transporter coiled coil Pkinase PF00069.25 KSA00593.1 - 1.1e-68 231.5 0.0 1.1e-68 231.5 0.0 2.0 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 KSA00593.1 - 1.8e-44 152.0 0.0 3.1e-44 151.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KSA00593.1 - 2.4e-07 29.9 1.1 7.4e-07 28.3 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 KSA00593.1 - 5e-07 29.3 0.5 2.8e-06 26.9 0.0 2.3 3 0 0 3 3 3 1 Kinase-like Kdo PF06293.14 KSA00593.1 - 0.008 15.6 0.0 0.016 14.6 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family WD40 PF00400.32 KSA00594.1 - 2.7e-39 132.4 7.4 4.4e-06 27.3 0.0 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KSA00594.1 - 2.3e-21 75.9 0.0 0.00014 22.0 0.1 5.5 2 1 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KSA00594.1 - 5.6e-10 38.5 0.7 0.0093 14.7 0.0 3.7 1 1 2 4 4 4 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KSA00594.1 - 7.9e-10 38.2 1.3 0.047 12.6 0.7 4.6 2 1 1 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KSA00594.1 - 4.7e-07 29.4 2.0 0.0057 16.0 0.0 3.9 4 0 0 4 4 4 2 WD40-like domain VID27 PF08553.10 KSA00594.1 - 0.0096 15.0 0.2 0.77 8.7 0.0 2.8 2 1 1 3 3 3 1 VID27 C-terminal WD40-like domain Frtz PF11768.8 KSA00594.1 - 0.017 13.5 0.1 0.063 11.6 0.1 2.0 3 0 0 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz PQQ PF01011.21 KSA00594.1 - 0.026 14.5 0.1 6.6 6.9 0.0 3.4 3 0 0 3 3 3 0 PQQ enzyme repeat Nbas_N PF15492.6 KSA00594.1 - 0.05 12.9 0.1 9 5.5 0.0 3.4 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal UPF0220 PF05255.11 KSA00595.1 - 9e-70 233.5 7.1 1e-69 233.3 7.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) Seadorna_VP7 PF07387.11 KSA00595.1 - 0.083 11.9 0.1 0.11 11.5 0.1 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase PF00069.25 KSA00596.1 - 1.4e-55 188.5 0.0 3.4e-55 187.3 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KSA00596.1 - 5.8e-26 91.3 0.0 7.9e-26 90.9 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KSA00596.1 - 0.0014 18.0 0.0 0.0021 17.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KSA00596.1 - 0.0018 17.7 0.0 0.0028 17.0 0.0 1.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4485 PF14846.6 KSA00596.1 - 0.025 14.6 0.2 0.054 13.5 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4485) APH PF01636.23 KSA00596.1 - 0.15 11.9 0.0 0.67 9.8 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Ribosomal_S11 PF00411.19 KSA00597.1 - 0.01 16.2 0.0 0.015 15.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein S11 CshA_NR2 PF18651.1 KSA00597.1 - 0.027 13.7 0.0 0.037 13.2 0.0 1.2 1 0 0 1 1 1 0 Surface adhesin CshA non-repetitive domain 2 Ribosomal_L23 PF00276.20 KSA00598.1 - 1.1e-12 48.1 1.9 6e-12 45.8 1.9 1.8 1 1 0 1 1 1 1 Ribosomal protein L23 USP7_ICP0_bdg PF12436.8 KSA00598.1 - 0.038 13.3 0.0 0.038 13.3 0.0 1.1 1 0 0 1 1 1 0 ICP0-binding domain of Ubiquitin-specific protease 7 Amidase PF01425.21 KSA00599.1 - 4.5e-89 299.5 0.0 6.3e-89 299.0 0.0 1.2 1 0 0 1 1 1 1 Amidase HAD_2 PF13419.6 KSA00600.1 - 2.3e-15 57.1 0.0 4.2e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KSA00600.1 - 2.6e-12 47.5 0.1 1e-07 32.5 0.0 2.6 2 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 KSA00600.1 - 2e-05 25.1 0.0 2.9e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KSA00600.1 - 0.0033 17.5 0.1 0.006 16.6 0.1 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 KSA00600.1 - 0.022 14.9 0.1 0.24 11.5 0.1 2.4 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Phage_attach PF05354.11 KSA00600.1 - 0.14 12.1 0.1 0.29 11.0 0.1 1.5 1 0 0 1 1 1 0 Phage Head-Tail Attachment Utp8 PF10395.9 KSA00601.1 - 2.4e-201 670.9 47.3 2.8e-201 670.7 47.3 1.0 1 0 0 1 1 1 1 Utp8 family DUF3819 PF12842.7 KSA00601.1 - 0.16 11.9 0.1 0.16 11.9 0.1 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3819) Complex1_LYR PF05347.15 KSA00602.1 - 0.023 14.7 0.1 0.046 13.8 0.1 1.5 1 0 0 1 1 1 0 Complex 1 protein (LYR family) PTS_2-RNA PF01885.16 KSA00603.1 - 2.2e-65 220.1 0.5 2.6e-65 219.9 0.5 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family MBD PF01429.19 KSA00604.1 - 0.007 16.1 0.2 0.15 11.8 0.0 2.2 2 0 0 2 2 2 1 Methyl-CpG binding domain RapH_N PF18801.1 KSA00604.1 - 0.087 12.9 1.1 0.15 12.1 1.1 1.4 1 0 0 1 1 1 0 response regulator aspartate phosphatase H, N terminal Elf1 PF05129.13 KSA00604.1 - 5.3 7.2 9.1 0.8 9.8 1.6 2.4 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like ANAPC_CDC26 PF10471.9 KSA00605.1 - 2.9e-12 47.2 3.5 3.6e-12 46.9 3.5 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex APC subunit CDC26 U3_snoRNA_assoc PF08297.11 KSA00606.1 - 7.6e-22 77.8 5.2 7.6e-22 77.8 5.2 3.0 2 1 0 2 2 2 1 U3 snoRNA associated CDC45 PF02724.14 KSA00606.1 - 2.2 6.5 17.5 2.4 6.3 17.5 1.2 1 0 0 1 1 1 0 CDC45-like protein F-box-like PF12937.7 KSA00607.1 - 4.7e-07 29.6 0.6 1e-06 28.5 0.6 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KSA00607.1 - 0.00057 19.7 0.5 0.0016 18.3 0.5 1.8 1 0 0 1 1 1 1 F-box domain TPR_2 PF07719.17 KSA00607.1 - 0.0012 18.8 0.8 1.6 9.1 0.5 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat LRR_6 PF13516.6 KSA00607.1 - 0.048 13.7 4.8 0.059 13.4 0.1 3.5 3 0 0 3 3 3 0 Leucine Rich repeat TPR_1 PF00515.28 KSA00607.1 - 0.051 13.4 2.6 0.35 10.8 0.9 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 KSA00607.1 - 0.067 13.5 0.1 1.5 9.2 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Zip PF02535.22 KSA00608.1 - 1.7e-26 93.2 16.9 1e-17 64.4 11.9 2.0 1 1 1 2 2 2 2 ZIP Zinc transporter DUF1129 PF06570.11 KSA00608.1 - 0.0016 18.0 4.5 0.34 10.4 0.5 2.5 1 1 2 3 3 3 2 Protein of unknown function (DUF1129) DUF4293 PF14126.6 KSA00608.1 - 3.4 7.9 9.7 9.7 6.4 6.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4293) DUF3336 PF11815.8 KSA00609.1 - 3.2e-34 117.6 4.8 3.2e-34 117.6 4.8 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.22 KSA00609.1 - 6.7e-23 81.9 0.0 1.7e-22 80.6 0.0 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase Lactamase_B_4 PF13691.6 KSA00610.1 - 5.9e-25 86.7 0.0 1.3e-24 85.6 0.0 1.6 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B_2 PF12706.7 KSA00610.1 - 0.00077 19.0 0.2 0.97 8.9 0.0 2.6 2 1 0 2 2 2 2 Beta-lactamase superfamily domain MRP-S26 PF14943.6 KSA00610.1 - 0.1 12.5 9.1 0.23 11.4 9.1 1.6 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 Pkinase PF00069.25 KSA00612.1 - 4.4e-62 209.8 0.1 5.1e-62 209.6 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KSA00612.1 - 4e-17 62.4 0.0 6.1e-17 61.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KSA00612.1 - 2.3e-07 31.0 0.0 4.2e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KSA00612.1 - 0.027 14.0 0.4 0.053 13.1 0.4 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 KSA00612.1 - 0.078 11.7 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Pro_isomerase PF00160.21 KSA00613.1 - 7.1e-47 159.6 0.1 1.1e-46 159.0 0.1 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.17 KSA00613.1 - 3.5e-06 26.7 5.2 0.00022 21.1 0.3 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KSA00613.1 - 4.9e-05 23.0 4.3 0.0044 16.8 0.2 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 KSA00613.1 - 0.00023 21.4 0.6 0.0016 18.7 1.4 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KSA00613.1 - 0.00098 19.2 5.1 0.009 16.2 0.4 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat MIT PF04212.18 KSA00613.1 - 0.015 15.4 7.6 0.37 10.9 0.1 2.5 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_14 PF13428.6 KSA00613.1 - 0.053 14.4 1.5 0.22 12.4 0.4 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 KSA00613.1 - 0.2 12.4 1.9 1.8 9.4 0.2 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat RNA_pol_Rpb1_1 PF04997.12 KSA00614.1 - 4.7e-113 377.7 0.1 1.2e-112 376.3 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 KSA00614.1 - 3.3e-109 364.4 0.1 4.8e-109 363.9 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KSA00614.1 - 9.2e-77 256.9 0.0 2.7e-76 255.4 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 KSA00614.1 - 8.6e-66 221.4 0.3 2e-65 220.3 0.3 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_7 PF04990.12 KSA00614.1 - 3.5e-51 172.7 3.4 3.5e-51 172.7 3.4 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_3 PF04983.18 KSA00614.1 - 4e-48 163.3 0.0 8.5e-48 162.2 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 KSA00614.1 - 7.9e-37 125.5 0.1 2.2e-36 124.1 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 KSA00614.1 - 3.8e-15 55.3 318.5 0.013 15.9 11.3 15.4 15 0 0 15 15 15 13 RNA polymerase Rpb1 C-terminal repeat SLATT_4 PF18186.1 KSA00614.1 - 0.048 13.3 0.0 0.091 12.4 0.0 1.4 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 4 RNase_P_pop3 PF08228.11 KSA00615.1 - 5.3e-20 72.1 0.2 7.4e-18 65.1 0.2 2.5 1 1 0 1 1 1 1 RNase P subunit Pop3 APP_E2 PF12925.7 KSA00615.1 - 0.0066 16.2 0.4 0.018 14.8 0.4 1.7 1 0 0 1 1 1 1 E2 domain of amyloid precursor protein Rep_fac_C PF08542.11 KSA00616.1 - 5e-23 81.3 0.0 5.2e-22 78.1 0.0 2.4 2 0 0 2 2 2 1 Replication factor C C-terminal domain AAA PF00004.29 KSA00616.1 - 4.8e-11 43.2 0.0 7.9e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 KSA00616.1 - 4.7e-10 39.5 0.1 1.3e-08 34.8 0.1 2.1 1 1 1 2 2 2 1 DNA polymerase III, delta subunit AAA_14 PF13173.6 KSA00616.1 - 1.7e-06 28.1 0.0 2.8e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KSA00616.1 - 4.8e-06 27.1 0.0 0.0006 20.2 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_3 PF07726.11 KSA00616.1 - 6.7e-06 26.0 0.0 1e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KSA00616.1 - 8.5e-06 25.6 0.0 2.5e-05 24.1 0.0 1.9 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KSA00616.1 - 2.2e-05 24.8 0.1 0.13 12.6 0.1 2.6 1 1 1 2 2 2 2 AAA domain Rad17 PF03215.15 KSA00616.1 - 0.00026 20.9 0.0 0.00057 19.9 0.0 1.5 1 1 0 1 1 1 1 Rad17 P-loop domain Viral_helicase1 PF01443.18 KSA00616.1 - 0.0034 17.1 0.0 0.0053 16.5 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Mg_chelatase PF01078.21 KSA00616.1 - 0.0046 16.4 0.0 0.061 12.7 0.0 2.1 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KSA00616.1 - 0.0087 16.1 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) TniB PF05621.11 KSA00616.1 - 0.015 14.7 0.1 4.2 6.7 0.0 2.5 2 0 0 2 2 2 0 Bacterial TniB protein AAA_assoc_2 PF16193.5 KSA00616.1 - 0.017 15.5 0.0 0.04 14.2 0.0 1.8 2 0 0 2 2 1 0 AAA C-terminal domain AAA_19 PF13245.6 KSA00616.1 - 0.075 13.4 0.2 1 9.7 0.1 2.3 1 1 1 2 2 2 0 AAA domain DNA_pol3_delta PF06144.13 KSA00616.1 - 0.081 12.7 0.3 0.12 12.1 0.3 1.2 1 0 0 1 1 1 0 DNA polymerase III, delta subunit MeaB PF03308.16 KSA00616.1 - 0.099 11.6 0.0 1.6 7.7 0.0 2.3 1 1 1 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NTPase_1 PF03266.15 KSA00616.1 - 0.11 12.4 0.0 0.51 10.2 0.0 2.0 2 0 0 2 2 2 0 NTPase AAA_24 PF13479.6 KSA00616.1 - 0.19 11.4 0.0 0.37 10.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Vps52 PF04129.12 KSA00617.1 - 3.8e-73 247.0 22.7 1.5e-49 169.1 11.3 2.6 3 0 0 3 3 3 2 Vps52 / Sac2 family Med10 PF09748.9 KSA00617.1 - 4.3 7.3 7.4 4.4 7.3 0.5 2.9 2 0 0 2 2 2 0 Transcription factor subunit Med10 of Mediator complex UvrD-helicase PF00580.21 KSA00618.1 - 3.9e-31 108.8 5.8 8.4e-29 101.1 0.0 3.3 2 2 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 KSA00618.1 - 1.9e-27 96.6 3.8 2.8e-27 96.0 2.4 2.0 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 KSA00618.1 - 2.9e-23 82.8 0.0 6.2e-23 81.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 KSA00618.1 - 3.2e-09 36.5 1.5 5.6e-08 32.5 1.5 2.3 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_12 PF13087.6 KSA00618.1 - 7.9e-07 28.9 0.0 0.082 12.5 0.0 3.5 4 0 0 4 4 4 2 AAA domain Viral_helicase1 PF01443.18 KSA00618.1 - 4.7e-06 26.5 0.1 0.12 12.1 0.0 3.7 3 1 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.6 KSA00618.1 - 8.7e-06 25.7 0.9 4.3e-05 23.4 0.0 2.5 3 0 0 3 3 3 1 AAA domain DUF4404 PF14357.6 KSA00618.1 - 0.03 14.9 1.6 2.2 9.0 0.3 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Helicase_RecD PF05127.14 KSA00618.1 - 0.13 12.1 0.0 0.35 10.7 0.0 1.8 2 0 0 2 2 2 0 Helicase CTD_bind PF04818.13 KSA00619.1 - 1.3e-20 74.0 0.7 3.3e-20 72.7 0.7 1.8 1 0 0 1 1 1 1 RNA polymerase II-binding domain. NPV_P10 PF05531.12 KSA00619.1 - 0.13 12.7 4.5 0.4 11.2 2.8 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Csm1 PF12539.8 KSA00620.1 - 1.2e-23 83.5 3.3 1.2e-23 83.5 3.3 2.4 2 1 0 2 2 2 1 Chromosome segregation protein Csm1/Pcs1 UPF0242 PF06785.11 KSA00620.1 - 0.0039 17.3 3.7 0.0039 17.3 3.7 1.8 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0242) N-terminus zf-LYAR PF08790.11 KSA00621.1 - 1.1e-15 57.1 5.2 1.1e-15 57.1 5.2 1.9 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger zf-TRAF PF02176.18 KSA00621.1 - 0.016 15.9 2.4 0.029 15.1 2.4 1.5 1 0 0 1 1 1 0 TRAF-type zinc finger zf_UBZ PF18439.1 KSA00621.1 - 0.027 14.0 0.6 1.5 8.5 0.1 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger DUF2981 PF11200.8 KSA00621.1 - 0.038 13.8 1.1 0.044 13.5 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Adaptin_binding PF10199.9 KSA00621.1 - 0.051 14.2 4.7 0.063 13.9 4.7 1.2 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 DM PF00751.18 KSA00621.1 - 0.15 12.0 3.3 0.29 11.1 3.3 1.5 1 0 0 1 1 1 0 DM DNA binding domain DUF4638 PF15472.6 KSA00621.1 - 0.46 10.2 13.4 0.61 9.8 13.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) PMSI1 PF15322.6 KSA00621.1 - 0.92 8.9 5.7 1.1 8.6 5.7 1.2 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative zf-C2H2_4 PF13894.6 KSA00621.1 - 1.1 10.3 6.0 19 6.4 0.3 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger SAM_Exu PF18609.1 KSA00621.1 - 1.3 9.1 4.2 0.64 10.2 1.4 2.0 1 1 1 2 2 2 0 Exuperantia SAM-like domain Neur_chan_memb PF02932.16 KSA00621.1 - 4.8 7.2 6.9 5.3 7.0 6.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region COX16 PF14138.6 KSA00622.1 - 4e-26 91.3 0.4 6.6e-26 90.6 0.4 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 Arc_PepC_II PF06847.11 KSA00622.1 - 0.12 13.0 0.6 0.32 11.5 0.0 1.9 1 1 1 2 2 2 0 Archaeal Peptidase A24 C-terminus Type II WD40 PF00400.32 KSA00623.1 - 4.6e-55 182.4 15.9 2.2e-10 40.9 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.10 KSA00623.1 - 1.2e-29 102.4 12.3 2.5e-29 101.4 12.3 1.6 1 0 0 1 1 1 1 Tup N-terminal ANAPC4_WD40 PF12894.7 KSA00623.1 - 7.7e-18 64.6 0.1 1.9e-05 24.9 0.0 5.6 2 1 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KSA00623.1 - 1.1e-06 28.2 0.1 0.016 14.5 0.0 4.9 4 1 1 5 5 5 1 WD40-like domain Ge1_WD40 PF16529.5 KSA00623.1 - 1.2e-05 24.5 0.1 0.59 9.0 0.0 4.2 1 1 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KSA00623.1 - 2.8e-05 23.0 7.6 0.99 8.0 0.1 4.8 1 1 4 5 5 5 4 Nucleoporin Nup120/160 Ret2_MD PF18528.1 KSA00623.1 - 0.0089 16.4 0.0 14 6.2 0.0 3.5 1 1 2 3 3 3 1 RNA editing 3' terminal uridylyl transferase 2 middle domain PD40 PF07676.12 KSA00623.1 - 0.015 15.2 0.0 31 4.6 0.0 4.3 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat IKI3 PF04762.12 KSA00623.1 - 0.016 13.2 1.8 0.018 13.1 0.0 2.0 2 1 0 2 2 2 0 IKI3 family Cytochrom_D1 PF02239.16 KSA00623.1 - 0.13 10.7 0.5 0.36 9.3 0.0 1.9 2 1 0 2 2 2 0 Cytochrome D1 heme domain Exonuc_VII_L PF02601.15 KSA00623.1 - 0.47 10.0 13.0 0.71 9.4 13.0 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF724 PF05266.14 KSA00623.1 - 1.6 8.5 12.2 3 7.7 12.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) MDD_C PF18376.1 KSA00624.1 - 8.4e-68 227.8 0.0 1.2e-67 227.2 0.0 1.3 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 KSA00624.1 - 3.5e-09 36.8 1.5 6.6e-09 35.9 1.0 1.8 2 0 0 2 2 2 1 GHMP kinases N terminal domain CDP-OH_P_transf PF01066.21 KSA00625.1 - 7.9e-16 58.6 0.5 7.9e-16 58.6 0.5 2.5 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF3169 PF11368.8 KSA00627.1 - 0.022 14.3 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) SLATT_1 PF18181.1 KSA00627.1 - 0.18 11.7 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 DUF5362 PF17319.2 KSA00627.1 - 3.3 7.6 7.4 9.7 6.1 7.3 1.9 1 1 1 2 2 2 0 Family of unknown function (DUF5362) bZIP_1 PF00170.21 KSA00629.1 - 8.9e-11 41.7 9.0 8.9e-11 41.7 9.0 1.6 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 KSA00629.1 - 2.9e-06 27.3 8.8 6.3e-06 26.2 8.8 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KSA00629.1 - 0.0066 16.9 6.7 0.014 15.9 6.7 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor DUF2012 PF09430.10 KSA00629.1 - 0.049 13.7 0.0 0.099 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2012) Cpn60_TCP1 PF00118.24 KSA00630.1 - 1.6e-148 495.4 8.8 1.8e-148 495.3 8.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Nitro_FeMo-Co PF02579.17 KSA00630.1 - 0.0014 18.9 0.0 0.019 15.3 0.0 2.4 2 0 0 2 2 2 1 Dinitrogenase iron-molybdenum cofactor PRAI PF00697.22 KSA00631.1 - 7.1e-46 156.4 0.1 1.7e-42 145.4 0.1 2.1 1 1 1 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase CMAS PF02353.20 KSA00631.1 - 0.041 13.2 0.0 0.056 12.7 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Vps53_N PF04100.12 KSA00632.1 - 1.3e-64 218.6 24.4 1.3e-64 218.6 24.4 2.5 2 1 0 2 2 2 1 Vps53-like, N-terminal Sec6 PF06046.13 KSA00632.1 - 4.9e-06 25.2 2.1 4.9e-06 25.2 2.1 2.9 3 0 0 3 3 3 2 Exocyst complex component Sec6 Ribosomal_L13 PF00572.18 KSA00633.1 - 1.5e-11 44.6 1.1 9.5e-10 38.8 0.2 2.5 2 1 0 2 2 2 1 Ribosomal protein L13 HMGL-like PF00682.19 KSA00635.1 - 4.5e-85 285.4 0.0 6.8e-85 284.8 0.0 1.2 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 KSA00635.1 - 5.8e-25 87.7 0.0 1.1e-24 86.9 0.0 1.5 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain RRM_1 PF00076.22 KSA00636.1 - 1.1e-43 146.9 0.0 1.3e-20 73.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KSA00636.1 - 0.00093 18.8 0.0 0.056 13.0 0.0 2.4 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KSA00636.1 - 0.0014 18.7 0.0 1.5 9.0 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 KSA00636.1 - 0.031 14.3 0.0 7.2 6.7 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif SR-25 PF10500.9 KSA00636.1 - 2.5 7.6 119.5 44 3.6 34.9 3.4 1 1 2 3 3 3 0 Nuclear RNA-splicing-associated protein Arrestin_N PF00339.29 KSA00637.1 - 9.1e-15 55.0 0.0 2.7e-14 53.5 0.0 1.8 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KSA00637.1 - 4.1e-09 37.0 0.7 9.9e-08 32.5 0.0 2.8 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Kelch_5 PF13854.6 KSA00638.1 - 6.3e-19 67.6 2.4 2.1e-08 33.9 0.3 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 KSA00638.1 - 1.9e-16 59.8 0.5 4.4e-05 23.4 0.1 3.5 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_3 PF13415.6 KSA00638.1 - 9.8e-16 57.6 0.0 4e-09 36.5 0.0 3.6 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.6 KSA00638.1 - 1.7e-15 56.7 3.4 1.5e-06 28.2 0.1 3.7 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.15 KSA00638.1 - 9e-15 54.0 1.0 1.1e-06 28.4 0.1 3.4 3 0 0 3 3 3 2 Kelch motif Kelch_1 PF01344.25 KSA00638.1 - 3.5e-14 52.1 0.4 1e-06 28.2 0.1 3.2 3 0 0 3 3 3 2 Kelch motif Sugar_tr PF00083.24 KSA00639.1 - 3.2e-114 382.3 22.0 3.7e-114 382.1 22.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KSA00639.1 - 1.3e-22 80.3 14.5 1.3e-22 80.3 14.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily FYVE PF01363.21 KSA00640.1 - 1.1e-22 79.9 25.8 3.7e-18 65.4 4.3 2.9 3 0 0 3 3 3 2 FYVE zinc finger Rbsn PF11464.8 KSA00640.1 - 1.2e-11 44.1 3.3 1.4e-11 43.9 1.1 2.2 2 0 0 2 2 2 1 Rabenosyn Rab binding domain zf-AN1 PF01428.16 KSA00640.1 - 0.00033 20.8 5.5 0.00033 20.8 5.5 3.3 4 0 0 4 4 4 1 AN1-like Zinc finger zf-Di19 PF05605.12 KSA00640.1 - 0.0066 16.7 0.1 0.0066 16.7 0.1 3.2 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 KSA00640.1 - 0.92 10.5 0.0 0.92 10.5 0.0 5.6 5 1 1 6 6 6 0 C2H2-type zinc finger HypA PF01155.19 KSA00640.1 - 7.6 6.6 11.0 35 4.5 4.2 3.5 3 0 0 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA ATP-synt_E PF05680.12 KSA00641.1 - 1.1e-27 96.2 0.3 1.2e-27 96.0 0.3 1.0 1 0 0 1 1 1 1 ATP synthase E chain Mn_catalase PF05067.12 KSA00641.1 - 0.041 12.9 0.1 0.047 12.6 0.1 1.0 1 0 0 1 1 1 0 Manganese containing catalase SpoIIE PF07228.12 KSA00642.1 - 7.2e-24 84.8 0.0 1.1e-23 84.2 0.0 1.3 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 KSA00642.1 - 4.9e-06 26.4 0.2 0.00026 20.7 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 KSA00642.1 - 0.00038 20.1 0.0 0.0011 18.7 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C Upf2 PF04050.14 KSA00643.1 - 2.2e-21 77.0 13.3 4.6e-21 76.0 11.4 2.7 1 1 1 2 2 2 1 Up-frameshift suppressor 2 MIF4G PF02854.19 KSA00643.1 - 3.3e-17 62.8 51.4 1.2e-12 48.0 14.8 5.0 5 1 0 5 5 5 3 MIF4G domain SDA1 PF05285.12 KSA00643.1 - 0.0033 16.9 34.6 0.0057 16.1 34.6 1.3 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.12 KSA00643.1 - 0.0042 15.4 35.5 0.0087 14.3 35.5 1.5 1 0 0 1 1 1 1 Nop14-like family CDC45 PF02724.14 KSA00643.1 - 0.045 12.0 22.3 0.081 11.2 22.3 1.4 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.13 KSA00643.1 - 0.56 10.3 31.7 1.9 8.6 31.7 1.9 1 0 0 1 1 1 0 YL1 nuclear protein RRN3 PF05327.11 KSA00643.1 - 0.92 8.0 34.4 0.21 10.1 24.1 2.9 3 0 0 3 3 3 0 RNA polymerase I specific transcription initiation factor RRN3 BUD22 PF09073.10 KSA00643.1 - 1.9 7.7 32.9 5 6.3 32.9 1.7 1 0 0 1 1 1 0 BUD22 PBP PF01161.20 KSA00644.1 - 2.2e-05 24.8 0.0 4.6e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Phage_HK97_TLTM PF06120.11 KSA00644.1 - 0.0039 16.4 1.2 0.0063 15.7 1.2 1.2 1 0 0 1 1 1 1 Tail length tape measure protein TcpS PF17456.2 KSA00644.1 - 0.38 10.8 2.7 0.77 9.8 2.4 1.7 1 1 0 1 1 1 0 Toxin-coregulated pilus protein S Fib_alpha PF08702.10 KSA00644.1 - 0.48 10.6 2.6 1 9.5 2.6 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family MTHFR PF02219.17 KSA00645.1 - 0.068 12.5 0.0 0.089 12.1 0.0 1.1 1 0 0 1 1 1 0 Methylenetetrahydrofolate reductase bZIP_1 PF00170.21 KSA00646.1 - 1.6e-08 34.5 10.8 6.1e-08 32.7 10.8 1.9 1 1 0 1 1 1 1 bZIP transcription factor Shugoshin_N PF07558.11 KSA00646.1 - 0.012 15.5 2.0 0.031 14.1 2.0 1.8 1 1 0 1 1 1 0 Shugoshin N-terminal coiled-coil region Tup_N PF08581.10 KSA00646.1 - 0.055 13.8 2.1 0.055 13.8 2.1 2.4 2 0 0 2 2 2 0 Tup N-terminal PsbQ PF05757.11 KSA00646.1 - 0.076 12.8 5.5 0.13 12.0 5.5 1.4 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) Macoilin PF09726.9 KSA00646.1 - 0.35 9.4 21.9 0.43 9.1 21.9 1.1 1 0 0 1 1 1 0 Macoilin family Glutaredoxin2_C PF04399.13 KSA00646.1 - 2.1 8.2 8.6 0.14 12.0 0.6 2.3 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain bZIP_2 PF07716.15 KSA00646.1 - 4 7.6 19.0 4.3 7.5 13.5 2.7 2 1 0 2 2 2 0 Basic region leucine zipper PAT1 PF09770.9 KSA00646.1 - 4.2 5.5 36.2 5.1 5.2 36.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4407 PF14362.6 KSA00646.1 - 7.4 5.8 20.8 11 5.2 20.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) COX5A PF02284.16 KSA00648.1 - 1e-41 141.1 2.1 1.4e-41 140.6 2.1 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va AAA_23 PF13476.6 KSA00648.1 - 0.035 14.6 0.1 0.041 14.4 0.1 1.1 1 0 0 1 1 1 0 AAA domain HTH_19 PF12844.7 KSA00648.1 - 0.042 13.9 0.4 0.092 12.8 0.4 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain ACP_PD PF04336.12 KSA00648.1 - 0.06 13.8 0.5 0.12 12.8 0.5 1.5 1 1 0 1 1 1 0 Acyl carrier protein phosphodiesterase DUF488 PF04343.13 KSA00648.1 - 0.066 13.8 4.1 0.5 11.0 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function, DUF488 PspA_IM30 PF04012.12 KSA00648.1 - 0.093 12.3 0.3 0.15 11.6 0.1 1.4 2 0 0 2 2 2 0 PspA/IM30 family TPR_7 PF13176.6 KSA00648.1 - 0.12 12.4 0.5 0.68 10.1 0.0 2.3 2 1 0 2 2 2 0 Tetratricopeptide repeat Mgr1 PF08602.10 KSA00649.1 - 7.9e-28 97.4 7.3 5.9e-16 58.3 0.0 3.4 1 1 2 3 3 3 3 Mgr1-like, i-AAA protease complex subunit DUF2153 PF09921.9 KSA00649.1 - 0.092 12.6 0.3 0.26 11.1 0.1 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2153) ING PF12998.7 KSA00652.1 - 1.6e-23 83.2 8.9 2e-23 82.9 8.2 1.5 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 KSA00652.1 - 1.6e-06 27.9 7.7 2.7e-06 27.2 7.7 1.4 1 0 0 1 1 1 1 PHD-finger Flagellar_rod PF05149.12 KSA00652.1 - 0.013 15.0 4.1 0.018 14.5 4.1 1.2 1 0 0 1 1 1 0 Paraflagellar rod protein PHD_2 PF13831.6 KSA00652.1 - 0.014 14.9 1.5 0.024 14.2 1.5 1.4 1 0 0 1 1 1 0 PHD-finger zf-HC5HC2H PF13771.6 KSA00652.1 - 0.02 15.2 0.2 0.046 14.0 0.2 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain dbPDZ_assoc PF16610.5 KSA00652.1 - 0.023 14.9 0.2 0.058 13.6 0.2 1.6 1 0 0 1 1 1 0 Unstructured region between two PDZ domains on Dlg5 zf-C4_Topoisom PF01396.19 KSA00652.1 - 1.7 8.5 6.4 4.5 7.1 0.9 2.5 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger Fib_alpha PF08702.10 KSA00652.1 - 7.6 6.7 9.7 6.1 7.0 7.8 1.7 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family UNC45-central PF11701.8 KSA00653.1 - 1e-28 100.2 5.4 1.3e-28 99.9 2.7 2.7 2 0 0 2 2 2 1 Myosin-binding striated muscle assembly central H-kinase_dim PF02895.14 KSA00653.1 - 0.04 14.3 0.1 0.21 12.0 0.1 2.3 1 0 0 1 1 1 0 Signal transducing histidine kinase, homodimeric domain Sec23_trunk PF04811.15 KSA00654.1 - 8.8e-39 133.5 0.0 1.5e-38 132.7 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 KSA00654.1 - 1.9e-20 72.6 0.3 4.6e-20 71.4 0.3 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 KSA00654.1 - 2.4e-17 63.5 0.0 5.4e-17 62.3 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 KSA00654.1 - 1.6e-10 40.8 8.9 3.1e-10 39.9 8.9 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KSA00654.1 - 0.0064 16.4 0.2 0.046 13.6 0.2 2.4 2 0 0 2 2 2 1 Gelsolin repeat PalH PF08733.10 KSA00655.1 - 1.3e-66 224.9 30.3 1.6e-66 224.6 30.3 1.1 1 0 0 1 1 1 1 PalH/RIM21 AAA_2 PF07724.14 KSA00656.1 - 3.1e-52 177.1 3.9 3e-51 173.9 0.0 3.0 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 KSA00656.1 - 3.5e-34 116.9 0.6 3.5e-34 116.9 0.6 2.6 2 1 0 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 KSA00656.1 - 5.2e-24 84.1 0.3 1.9e-23 82.3 0.1 2.2 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 KSA00656.1 - 1.2e-21 77.6 0.2 1.9e-11 44.5 0.1 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KSA00656.1 - 6.2e-16 58.6 0.4 8.5e-11 42.0 0.0 3.2 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KSA00656.1 - 1.7e-13 51.3 0.1 9.7e-05 22.8 0.0 4.7 3 1 1 4 4 4 2 AAA ATPase domain Sigma54_activat PF00158.26 KSA00656.1 - 2.6e-08 33.8 0.1 4.9e-05 23.1 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_7 PF12775.7 KSA00656.1 - 8.6e-08 31.9 0.1 0.011 15.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_22 PF13401.6 KSA00656.1 - 1e-07 32.3 2.1 0.011 16.0 0.1 4.0 3 2 1 4 4 3 2 AAA domain AAA_14 PF13173.6 KSA00656.1 - 3.4e-07 30.4 1.5 0.0087 16.1 0.0 3.5 3 0 0 3 3 3 2 AAA domain IstB_IS21 PF01695.17 KSA00656.1 - 8.5e-06 25.6 0.1 0.038 13.7 0.0 2.9 3 0 0 3 3 2 2 IstB-like ATP binding protein ResIII PF04851.15 KSA00656.1 - 1.7e-05 24.9 0.3 0.62 10.1 0.0 3.7 2 1 0 3 3 3 2 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KSA00656.1 - 1.8e-05 24.6 0.1 0.054 13.2 0.2 3.1 2 1 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 KSA00656.1 - 2.6e-05 24.3 11.8 0.32 10.9 0.1 4.4 3 2 2 5 5 4 3 ATPase domain predominantly from Archaea AAA_28 PF13521.6 KSA00656.1 - 3.9e-05 23.9 0.2 0.72 10.1 0.0 3.8 3 1 0 3 3 3 2 AAA domain RNA_helicase PF00910.22 KSA00656.1 - 4.1e-05 23.9 1.3 0.57 10.6 0.0 3.7 4 1 0 4 4 3 2 RNA helicase TniB PF05621.11 KSA00656.1 - 4.3e-05 23.0 0.1 0.02 14.3 0.1 3.5 2 1 0 2 2 2 1 Bacterial TniB protein NACHT PF05729.12 KSA00656.1 - 9.7e-05 22.3 0.1 0.7 9.8 0.0 2.8 3 0 0 3 3 2 2 NACHT domain DUF815 PF05673.13 KSA00656.1 - 0.00011 21.5 2.7 0.034 13.3 0.3 3.6 2 2 0 2 2 2 1 Protein of unknown function (DUF815) TsaE PF02367.17 KSA00656.1 - 0.00033 20.6 0.0 1.6 8.8 0.0 2.7 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.6 KSA00656.1 - 0.00047 20.5 0.5 0.4 11.0 0.0 3.6 2 1 0 2 2 2 1 AAA domain TrwB_AAD_bind PF10412.9 KSA00656.1 - 0.00075 18.5 0.3 0.12 11.3 0.1 2.9 2 1 1 3 3 3 1 Type IV secretion-system coupling protein DNA-binding domain DUF853 PF05872.12 KSA00656.1 - 0.00088 18.0 0.1 0.031 12.9 0.0 2.4 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF853) Torsin PF06309.11 KSA00656.1 - 0.00098 19.2 0.0 0.048 13.8 0.0 2.4 2 0 0 2 2 2 1 Torsin PhoH PF02562.16 KSA00656.1 - 0.0014 18.1 0.0 1.1 8.6 0.0 2.6 2 0 0 2 2 2 1 PhoH-like protein AAA_6 PF12774.7 KSA00656.1 - 0.0015 17.5 0.0 0.075 12.0 0.0 2.5 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region AAA_18 PF13238.6 KSA00656.1 - 0.0016 19.0 2.6 0.66 10.5 0.0 3.3 3 0 0 3 3 2 1 AAA domain Zeta_toxin PF06414.12 KSA00656.1 - 0.0023 17.2 0.1 0.14 11.4 0.0 2.7 3 0 0 3 3 2 1 Zeta toxin AAA_24 PF13479.6 KSA00656.1 - 0.003 17.3 0.2 1.7 8.3 0.0 2.6 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 KSA00656.1 - 0.0032 16.9 0.1 2.3 7.6 0.0 3.0 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI SRP54 PF00448.22 KSA00656.1 - 0.0036 17.0 0.1 2.3 7.8 0.0 3.2 3 0 0 3 3 2 1 SRP54-type protein, GTPase domain Roc PF08477.13 KSA00656.1 - 0.0041 17.3 0.1 2.6 8.3 0.0 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase PduV-EutP PF10662.9 KSA00656.1 - 0.0075 16.0 0.0 1.2 8.8 0.0 2.6 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Orbi_NS1 PF01718.16 KSA00656.1 - 0.011 14.2 0.0 0.019 13.5 0.0 1.2 1 0 0 1 1 1 0 Orbivirus non-structural protein NS1, or hydrophobic tubular protein T2SSE PF00437.20 KSA00656.1 - 0.012 14.7 0.1 0.3 10.1 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_33 PF13671.6 KSA00656.1 - 0.017 15.3 0.0 6.2 7.0 0.0 2.9 2 0 0 2 2 2 0 AAA domain Ribosomal_L9_C PF03948.14 KSA00656.1 - 0.02 15.4 0.0 0.086 13.3 0.0 2.1 1 0 0 1 1 1 0 Ribosomal protein L9, C-terminal domain RsgA_GTPase PF03193.16 KSA00656.1 - 0.028 14.3 0.0 14 5.5 0.0 3.0 2 0 0 2 2 2 0 RsgA GTPase ABC_tran PF00005.27 KSA00656.1 - 0.029 14.9 4.8 0.44 11.0 0.0 3.9 3 2 0 3 3 3 0 ABC transporter Bac_DnaA PF00308.18 KSA00656.1 - 0.055 13.3 0.0 8.6 6.1 0.0 2.6 2 0 0 2 2 2 0 Bacterial dnaA protein PilJ PF13675.6 KSA00656.1 - 0.085 12.9 2.6 0.21 11.6 0.9 2.3 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term AAA_21 PF13304.6 KSA00656.1 - 0.086 12.6 3.0 0.64 9.8 0.0 3.3 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF87 PF01935.17 KSA00656.1 - 0.17 12.0 13.0 0.4 10.7 0.0 4.0 4 1 0 4 4 3 0 Helicase HerA, central domain UvrD-helicase PF00580.21 KSA00656.1 - 0.49 9.9 0.0 0.49 9.9 0.0 2.7 2 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain Prefoldin PF02996.17 KSA00656.1 - 0.77 9.7 7.7 1.5 8.8 0.1 4.2 4 1 0 4 4 4 0 Prefoldin subunit SlyX PF04102.12 KSA00656.1 - 1.4 9.6 6.2 32 5.2 2.2 3.4 3 0 0 3 3 2 0 SlyX FlxA PF14282.6 KSA00656.1 - 4.5 7.3 12.7 11 6.1 6.9 2.6 1 1 1 2 2 2 0 FlxA-like protein EF-hand_4 PF12763.7 KSA00657.1 - 2.3e-22 78.9 0.0 3.4e-12 46.2 0.0 2.6 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand DUF1720 PF08226.11 KSA00657.1 - 1.4e-21 76.6 195.0 3.2e-09 37.1 16.0 9.4 5 2 4 9 9 9 7 Domain of unknown function (DUF1720) EF-hand_1 PF00036.32 KSA00657.1 - 4.2e-09 35.3 0.0 0.001 18.4 0.0 3.5 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 KSA00657.1 - 1.4e-06 28.7 0.0 0.0022 18.4 0.0 3.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KSA00657.1 - 5.6e-05 22.7 0.3 0.57 10.3 0.0 3.9 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 KSA00657.1 - 0.0006 19.6 0.0 0.031 14.1 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain pair WH2 PF02205.20 KSA00657.1 - 0.0053 16.6 0.2 0.014 15.2 0.2 1.7 1 0 0 1 1 1 1 WH2 motif Phos_pyr_kin PF08543.12 KSA00658.1 - 2.6e-67 226.8 0.0 5.8e-67 225.6 0.0 1.6 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.16 KSA00658.1 - 2.6e-38 132.0 1.1 3.9e-38 131.4 1.1 1.3 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.24 KSA00658.1 - 0.00012 21.5 0.0 0.067 12.5 0.0 2.2 2 0 0 2 2 2 2 pfkB family carbohydrate kinase HK PF02110.15 KSA00658.1 - 0.13 11.6 0.0 3.6 6.9 0.0 2.1 2 0 0 2 2 2 0 Hydroxyethylthiazole kinase family Carb_kinase PF01256.17 KSA00658.1 - 0.17 11.4 0.0 0.37 10.2 0.0 1.7 1 1 0 1 1 1 0 Carbohydrate kinase Vac_Fusion PF02346.16 KSA00658.1 - 0.72 9.5 2.6 3.7 7.2 0.1 2.9 3 0 0 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 A_deaminase PF00962.22 KSA00659.1 - 5e-120 400.7 0.1 7.1e-120 400.2 0.1 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase Rgp1 PF08737.10 KSA00660.1 - 4e-23 82.3 3.9 1.8e-21 76.8 0.4 3.0 2 1 0 2 2 2 1 Rgp1 Arrestin_C PF02752.22 KSA00660.1 - 1.3e-06 28.9 0.1 8.1e-06 26.3 0.3 2.3 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Pkinase PF00069.25 KSA00661.1 - 9.6e-68 228.4 0.0 1.7e-67 227.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KSA00661.1 - 1.7e-31 109.5 0.0 3.4e-31 108.5 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KSA00661.1 - 8.6e-06 24.9 0.1 1.4e-05 24.3 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KSA00661.1 - 0.00031 20.1 0.2 0.0017 17.7 0.2 1.9 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KSA00661.1 - 0.0011 19.0 0.1 0.0035 17.3 0.0 1.8 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KSA00661.1 - 0.0014 18.0 0.0 0.011 15.1 0.0 2.2 2 1 0 3 3 3 1 Kinase-like FTA2 PF13095.6 KSA00661.1 - 0.022 14.4 0.0 0.036 13.7 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 KSA00661.1 - 0.11 12.0 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 RIO1 family WD40 PF00400.32 KSA00662.1 - 1.4e-12 47.9 9.8 0.0011 19.7 0.3 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KSA00662.1 - 1.9e-10 40.9 2.4 5.5e-05 23.4 0.2 3.6 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KSA00662.1 - 0.0002 20.4 0.0 0.096 11.6 0.0 3.2 2 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Snf7 PF03357.21 KSA00663.1 - 2.8e-29 101.9 12.7 3.2e-29 101.7 12.7 1.0 1 0 0 1 1 1 1 Snf7 Exog_C PF18026.1 KSA00663.1 - 0.16 12.1 3.2 0.2 11.7 1.1 2.2 2 0 0 2 2 2 0 Endo/exonuclease (EXOG) C-terminal domain Peptidase_M13_N PF05649.13 KSA00663.1 - 0.27 10.9 5.3 0.36 10.5 5.1 1.2 1 1 0 1 1 1 0 Peptidase family M13 ALAD PF00490.21 KSA00664.1 - 3.1e-118 394.6 0.0 3.7e-118 394.3 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase PQ-loop PF04193.14 KSA00665.1 - 1.2e-17 63.4 6.1 2e-12 46.7 0.2 3.3 2 1 0 2 2 2 2 PQ loop repeat ER_lumen_recept PF00810.18 KSA00665.1 - 0.00065 20.5 1.0 0.00065 20.5 1.0 2.0 1 1 1 2 2 2 1 ER lumen protein retaining receptor Nsp1_C PF05064.13 KSA00666.1 - 8.9e-41 138.3 8.7 8.9e-41 138.3 8.7 2.4 2 1 0 2 2 2 1 Nsp1-like C-terminal region APG6_N PF17675.1 KSA00666.1 - 0.018 15.5 2.1 0.018 15.5 2.1 3.0 3 1 0 3 3 3 0 Apg6 coiled-coil region Nucleoporin_FG PF13634.6 KSA00666.1 - 0.023 15.5 5.3 0.092 13.6 5.3 2.0 1 0 0 1 1 1 0 Nucleoporin FG repeat region Nup_retrotrp_bd PF10599.9 KSA00666.1 - 0.58 10.9 8.7 1.3 9.7 0.8 3.2 2 1 1 3 3 3 0 Retro-transposon transporting motif bMG5 PF17972.1 KSA00666.1 - 1.8 9.0 4.9 15 5.9 0.5 3.3 2 1 1 3 3 3 0 Bacterial Alpha-2-macroglobulin MG5 domain CorA PF01544.18 KSA00666.1 - 3 7.1 12.1 1.5 8.1 2.8 2.5 2 1 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF1664 PF07889.12 KSA00666.1 - 4.4 7.3 12.2 1.3 9.1 2.4 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) FoP_duplication PF13865.6 KSA00666.1 - 7.4 7.2 10.7 0.46 11.1 0.9 3.1 3 0 0 3 3 3 0 C-terminal duplication domain of Friend of PRMT1 tRNA-synt_2d PF01409.20 KSA00667.1 - 8.2e-27 94.2 0.0 1.3e-25 90.3 0.0 2.1 1 1 1 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 KSA00667.1 - 3.8e-24 84.9 0.1 7.2e-24 84.0 0.0 1.5 2 0 0 2 2 2 1 Ferredoxin-fold anticodon binding domain Ribosomal_L16 PF00252.18 KSA00668.1 - 6.6e-35 120.0 0.4 9e-35 119.6 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e sCache_like PF16736.5 KSA00668.1 - 0.11 12.5 0.1 0.24 11.5 0.1 1.6 1 0 0 1 1 1 0 Single Cache-like BLOC1_2 PF10046.9 KSA00669.1 - 3e-09 37.1 3.2 4e-09 36.7 3.0 1.3 1 1 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Exonuc_VII_S PF02609.16 KSA00669.1 - 0.05 13.7 0.1 0.1 12.7 0.1 1.5 1 0 0 1 1 1 0 Exonuclease VII small subunit Snf7 PF03357.21 KSA00670.1 - 1.9e-26 92.7 16.9 3.4e-26 91.9 16.9 1.3 1 0 0 1 1 1 1 Snf7 Eno-Rase_FAD_bd PF07055.12 KSA00670.1 - 0.062 13.7 2.0 0.25 11.8 2.0 2.1 1 0 0 1 1 1 0 Enoyl reductase FAD binding domain Baculo_F PF12259.8 KSA00670.1 - 0.35 9.4 6.8 0.1 11.1 0.3 2.0 1 1 0 2 2 2 0 Baculovirus F protein DUF948 PF06103.11 KSA00670.1 - 4.7 7.6 6.1 1.5e+02 2.7 6.1 3.0 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Pmp3 PF01679.17 KSA00671.1 - 3.1e-10 40.1 7.6 4e-10 39.7 7.6 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator DUF131 PF01998.17 KSA00671.1 - 2 8.2 7.3 0.35 10.5 2.5 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF131 DNA_pol3_delta2 PF13177.6 KSA00672.1 - 8.3e-11 41.9 0.7 2.5e-10 40.3 0.7 1.8 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 KSA00672.1 - 6.2e-08 33.1 1.5 3e-07 30.9 0.6 2.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KSA00672.1 - 5.2e-07 30.0 0.3 0.00056 20.2 0.1 3.3 3 1 0 3 3 3 1 AAA domain Rad17 PF03215.15 KSA00672.1 - 1.6e-05 24.9 0.1 3.5e-05 23.8 0.1 1.8 1 1 0 1 1 1 1 Rad17 P-loop domain RuvB_N PF05496.12 KSA00672.1 - 0.0048 16.6 0.0 0.34 10.6 0.0 2.7 2 1 1 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 KSA00672.1 - 0.0053 16.2 0.0 0.063 12.7 0.0 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 KSA00672.1 - 0.012 16.0 0.0 0.047 14.1 0.0 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.6 KSA00672.1 - 0.013 15.9 0.0 0.027 14.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KSA00672.1 - 0.017 14.8 0.3 0.058 13.1 0.3 1.8 1 1 0 1 1 1 0 AAA domain DUF2247 PF10004.9 KSA00672.1 - 0.019 14.8 0.3 0.47 10.2 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2247) AAA_11 PF13086.6 KSA00672.1 - 0.032 14.0 1.3 0.48 10.2 1.3 2.6 1 1 0 1 1 1 0 AAA domain CS PF04969.16 KSA00672.1 - 6.4 7.9 7.6 12 6.9 0.1 3.8 3 3 1 4 4 4 0 CS domain PMSR PF01625.21 KSA00673.1 - 1.4e-56 190.9 0.2 1.7e-56 190.7 0.2 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase UCH PF00443.29 KSA00674.1 - 1.7e-52 178.5 9.9 8.9e-52 176.1 9.9 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KSA00674.1 - 1.3e-25 90.7 10.1 1.2e-21 77.7 4.2 3.7 4 0 0 4 4 4 2 Ubiquitin carboxyl-terminal hydrolase zf_C2H2_ZHX PF18387.1 KSA00674.1 - 0.59 9.8 3.5 2.3 7.9 0.2 3.0 3 0 0 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain GST_N PF02798.20 KSA00675.1 - 2.7e-15 56.4 0.0 2.7e-14 53.3 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KSA00675.1 - 5.8e-13 48.9 0.0 1e-11 44.9 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KSA00675.1 - 3.3e-12 46.6 0.0 5.7e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KSA00675.1 - 1.3e-08 34.9 0.0 2.8e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KSA00675.1 - 1.4e-08 34.9 0.0 2.3e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KSA00675.1 - 0.01 15.9 0.0 0.019 15.0 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Zn_clus PF00172.18 KSA00676.1 - 1.8e-05 24.8 12.2 5.1e-05 23.3 12.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PhyH PF05721.13 KSA00677.1 - 4.8e-12 46.6 0.0 2.8e-11 44.1 0.0 2.0 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) GFO_IDH_MocA PF01408.22 KSA00678.1 - 7.3e-20 72.0 0.0 1e-19 71.5 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 KSA00678.1 - 0.024 15.3 0.0 0.041 14.5 0.0 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain E1_4HB PF16191.5 KSA00678.1 - 0.15 12.3 0.1 0.28 11.4 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin-activating enzyme E1 four-helix bundle Sugar_tr PF00083.24 KSA00679.1 - 1.7e-150 501.8 32.8 2e-150 501.6 32.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KSA00679.1 - 2.1e-28 99.3 32.5 9.1e-25 87.3 19.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KSA00679.1 - 0.00066 18.2 3.3 0.0011 17.4 3.3 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Ni_hydr_CYTB PF01292.20 KSA00679.1 - 0.14 11.7 4.0 0.19 11.3 1.0 2.4 2 1 0 2 2 2 0 Prokaryotic cytochrome b561 NAD_binding_10 PF13460.6 KSA00680.1 - 1.9e-41 142.0 0.7 2.3e-41 141.7 0.7 1.0 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KSA00680.1 - 1.3e-09 38.0 0.9 1.5e-08 34.5 0.9 2.0 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KSA00680.1 - 2e-09 37.3 0.2 1.2e-08 34.7 0.1 2.0 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KSA00680.1 - 3e-05 23.3 0.0 0.11 11.7 0.0 2.2 1 1 0 2 2 2 2 Male sterility protein Sacchrp_dh_NADP PF03435.18 KSA00680.1 - 3.8e-05 23.9 0.3 6.6e-05 23.2 0.3 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain DapB_N PF01113.20 KSA00680.1 - 0.00018 21.6 0.4 0.0003 20.9 0.4 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus 3Beta_HSD PF01073.19 KSA00680.1 - 0.0002 20.4 0.1 0.00028 20.0 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KSA00680.1 - 0.0034 16.6 0.3 0.018 14.2 0.3 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.24 KSA00680.1 - 0.028 14.9 0.1 0.046 14.2 0.1 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 KSA00680.1 - 0.041 13.0 0.0 0.065 12.3 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Ldh_1_N PF00056.23 KSA00680.1 - 0.051 13.7 0.4 0.12 12.5 0.4 1.6 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain MFS_1 PF07690.16 KSA00681.1 - 1.2e-31 110.0 22.8 1.2e-31 110.0 22.8 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KSA00681.1 - 1.5e-30 106.5 21.6 3.1e-30 105.4 21.6 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter DUF4079 PF13301.6 KSA00681.1 - 0.0029 17.8 0.2 0.2 11.8 0.0 2.8 2 1 0 2 2 2 1 Protein of unknown function (DUF4079) Abhydrolase_9_N PF15420.6 KSA00681.1 - 0.011 15.8 1.2 0.018 15.0 0.2 2.0 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus Sugar_tr PF00083.24 KSA00682.1 - 1.1e-93 314.5 22.8 1.5e-93 314.1 22.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KSA00682.1 - 1.6e-25 89.8 30.5 4.8e-17 61.9 14.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KSA00682.1 - 0.003 16.0 2.5 0.003 16.0 2.5 2.0 2 1 1 3 3 3 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 KSA00682.1 - 0.28 9.4 11.9 0.27 9.5 5.1 3.0 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF3100 PF11299.8 KSA00682.1 - 0.66 9.3 5.5 0.36 10.2 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3100) AA_permease_2 PF13520.6 KSA00683.1 - 1.8e-63 214.9 51.7 2.2e-63 214.6 51.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KSA00683.1 - 2.7e-11 42.7 42.3 3.9e-11 42.2 42.3 1.1 1 0 0 1 1 1 1 Amino acid permease DUF2976 PF11190.8 KSA00683.1 - 5.1 7.0 7.9 1.8 8.4 0.2 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2976) TauD PF02668.16 KSA00684.1 - 1.3e-41 143.1 0.0 1.8e-41 142.7 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Phosphoesterase PF04185.14 KSA00685.1 - 0.002 17.4 2.1 0.023 13.9 0.3 2.6 2 1 0 2 2 2 1 Phosphoesterase family Phosphoesterase PF04185.14 KSA00686.1 - 1.4e-21 77.1 0.3 1.8e-21 76.7 0.3 1.1 1 0 0 1 1 1 1 Phosphoesterase family PBP PF01161.20 KSA00687.1 - 2.9e-15 56.8 0.0 3.4e-15 56.5 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Pyr_redox_2 PF07992.14 KSA00688.1 - 1.7e-09 37.3 0.0 1.9e-09 37.2 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KSA00688.1 - 1.3e-06 28.8 0.0 1.8e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KSA00688.1 - 0.046 12.9 0.0 0.049 12.8 0.0 1.1 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Tannase PF07519.11 KSA00690.1 - 1.2e-131 439.8 1.5 1.5e-131 439.6 1.5 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Cupin_5 PF06172.11 KSA00691.1 - 1.7e-46 157.9 0.0 2.1e-46 157.6 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily (DUF985) Fungal_trans PF04082.18 KSA00692.1 - 2.1e-25 89.3 0.4 2.1e-25 89.3 0.4 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KSA00692.1 - 0.00057 19.9 15.4 0.0013 18.9 15.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.25 KSA00693.1 - 1.3e-43 148.7 0.0 1.7e-43 148.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KSA00693.1 - 8.1e-25 87.7 0.0 1e-24 87.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KSA00693.1 - 4.3e-13 49.6 0.0 5.8e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KSA00693.1 - 0.00024 20.6 0.1 0.0017 17.8 0.0 2.2 1 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KSA00693.1 - 0.0012 18.7 0.0 0.0025 17.7 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KSA00693.1 - 0.0073 15.7 0.3 0.058 12.8 0.1 2.3 3 0 0 3 3 3 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KSA00693.1 - 0.01 15.4 0.0 0.037 13.6 0.0 1.8 2 0 0 2 2 2 0 NmrA-like family Polysacc_synt_2 PF02719.15 KSA00693.1 - 0.018 14.2 0.0 0.052 12.7 0.0 1.7 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KSA00693.1 - 0.02 14.0 0.0 0.037 13.1 0.0 1.5 1 0 0 1 1 1 0 RmlD substrate binding domain Eno-Rase_NADH_b PF12242.8 KSA00693.1 - 0.13 12.0 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase TPR_4 PF07721.14 KSA00693.1 - 0.2 12.4 0.4 0.44 11.3 0.4 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat ADH_zinc_N PF00107.26 KSA00695.1 - 6.5e-10 39.1 0.0 7.2e-10 38.9 0.0 1.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KSA00695.1 - 0.1 13.6 0.0 0.11 13.5 0.0 1.1 1 0 0 1 1 1 0 Zinc-binding dehydrogenase ADH_N PF08240.12 KSA00696.1 - 1.7e-05 24.7 0.0 1.8e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Sugar_tr PF00083.24 KSA00697.1 - 2.7e-83 280.3 24.2 3.3e-83 280.1 24.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KSA00697.1 - 2.1e-21 76.3 25.6 2.1e-21 76.3 25.6 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily ADH_N PF08240.12 KSA00698.1 - 2.2e-27 95.1 4.0 4e-27 94.3 4.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KSA00698.1 - 2.9e-16 59.6 0.0 4.4e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KSA00698.1 - 7.5e-07 28.8 0.1 0.00015 21.3 0.0 2.2 2 0 0 2 2 2 2 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KSA00698.1 - 0.00044 21.3 0.0 0.001 20.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox_2 PF07992.14 KSA00698.1 - 0.022 14.0 0.0 0.061 12.5 0.0 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KSA00698.1 - 0.032 14.5 0.0 0.055 13.7 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain AdoHcyase_NAD PF00670.21 KSA00698.1 - 0.08 13.0 0.1 0.21 11.7 0.0 1.8 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 KSA00698.1 - 0.095 12.1 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KSA00698.1 - 0.12 12.7 0.0 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain adh_short_C2 PF13561.6 KSA00699.1 - 1e-54 185.6 0.0 1.2e-54 185.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KSA00699.1 - 2.6e-41 141.2 0.1 3.4e-41 140.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KSA00699.1 - 3.3e-13 49.9 0.1 5.3e-13 49.3 0.1 1.2 1 0 0 1 1 1 1 KR domain Spermine_synth PF01564.17 KSA00699.1 - 0.044 13.2 0.2 0.07 12.5 0.2 1.2 1 0 0 1 1 1 0 Spermine/spermidine synthase domain MMR_HSR1 PF01926.23 KSA00700.1 - 3e-14 53.1 0.0 7.7e-14 51.7 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KSA00700.1 - 2.1e-07 30.7 0.1 3.9e-07 29.8 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KSA00700.1 - 3.9e-07 30.1 0.3 5e-06 26.5 0.0 2.4 2 1 1 3 3 3 1 RsgA GTPase IIGP PF05049.13 KSA00700.1 - 3.6e-06 26.3 0.3 6e-06 25.6 0.3 1.3 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Septin PF00735.18 KSA00700.1 - 9.4e-05 21.8 0.5 0.0014 17.9 0.0 2.3 2 0 0 2 2 2 1 Septin FeoB_N PF02421.18 KSA00700.1 - 0.00013 21.5 0.4 0.00063 19.3 0.3 2.2 1 1 1 2 2 2 1 Ferrous iron transport protein B AIG1 PF04548.16 KSA00700.1 - 0.00083 18.7 0.0 0.0016 17.8 0.0 1.5 1 0 0 1 1 1 1 AIG1 family SRPRB PF09439.10 KSA00700.1 - 0.0016 17.9 0.0 0.0048 16.3 0.0 1.8 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 KSA00700.1 - 0.0033 17.6 0.0 0.0082 16.4 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KSA00700.1 - 0.0077 15.8 0.1 0.02 14.5 0.1 1.8 1 1 0 1 1 1 1 Ras family Dynamin_N PF00350.23 KSA00700.1 - 0.029 14.4 5.0 0.12 12.5 0.7 3.2 2 1 0 2 2 2 0 Dynamin family PLDc PF00614.22 KSA00701.1 - 3.6e-16 58.6 0.0 2.2e-07 30.8 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 KSA00701.1 - 7.1e-14 51.8 0.1 3.6e-07 30.1 0.0 2.9 2 1 0 2 2 2 2 PLD-like domain PH PF00169.29 KSA00701.1 - 0.023 15.2 0.1 0.14 12.7 0.1 2.4 2 0 0 2 2 2 0 PH domain Erv26 PF04148.13 KSA00702.1 - 1.1e-80 270.3 9.0 1.5e-80 269.9 9.0 1.2 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 Cyt_bd_oxida_II PF02322.15 KSA00702.1 - 0.00091 18.7 5.6 0.0011 18.4 5.6 1.1 1 0 0 1 1 1 1 Cytochrome bd terminal oxidase subunit II SecG PF03840.14 KSA00702.1 - 1.3 9.1 0.1 1.3 9.1 0.1 2.9 3 0 0 3 3 3 0 Preprotein translocase SecG subunit Abhydrolase_1 PF00561.20 KSA00703.1 - 2.8e-44 151.7 0.0 1.1e-43 149.7 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 KSA00703.1 - 0.0028 17.3 0.0 0.0047 16.6 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Apc15p PF05841.11 KSA00703.1 - 0.1 13.4 0.0 0.2 12.5 0.0 1.3 1 0 0 1 1 1 0 Apc15p protein Scs3p PF10261.9 KSA00704.1 - 3.2e-27 95.6 0.8 3.2e-27 95.6 0.8 1.4 1 1 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM E1-E2_ATPase PF00122.20 KSA00705.1 - 3.1e-46 157.2 0.0 3.1e-46 157.2 0.0 3.1 3 1 1 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 KSA00705.1 - 3e-33 115.9 0.0 5.2e-33 115.1 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 KSA00705.1 - 7.9e-20 71.1 5.9 2.6e-09 37.4 0.1 5.0 4 0 0 4 4 4 3 Heavy-metal-associated domain TMEM65 PF10507.9 KSA00705.1 - 0.0097 15.8 0.2 0.19 11.7 0.0 2.7 2 0 0 2 2 2 1 Transmembrane protein 65 HAD PF12710.7 KSA00705.1 - 0.038 14.4 0.0 0.091 13.2 0.0 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF5056 PF16479.5 KSA00705.1 - 0.059 13.6 0.1 0.5 10.6 0.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF5056) Hydrolase_3 PF08282.12 KSA00705.1 - 0.24 11.1 9.4 0.11 12.2 0.2 3.3 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase PP2C PF00481.21 KSA00706.1 - 6.6e-65 219.3 1.6 8.9e-64 215.6 1.6 2.2 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KSA00706.1 - 0.1 12.5 0.1 0.29 11.0 0.1 1.8 1 1 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) Hydrolase_4 PF12146.8 KSA00707.1 - 1.8e-41 142.0 0.0 2.4e-41 141.6 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KSA00707.1 - 7.6e-13 48.7 0.0 1e-11 45.0 0.0 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KSA00707.1 - 5.6e-09 36.9 0.0 7.1e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 KSA00707.1 - 0.0079 16.0 0.1 0.33 10.7 0.0 2.7 3 0 0 3 3 3 1 Alpha/beta hydrolase family DUF1749 PF08538.10 KSA00707.1 - 0.017 14.2 0.1 0.091 11.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) Chlorophyllase PF07224.11 KSA00707.1 - 0.063 12.3 0.0 0.094 11.7 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Peptidase_S9 PF00326.21 KSA00707.1 - 0.088 12.3 0.1 1.7 8.1 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 KSA00707.1 - 0.11 11.4 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_3 PF07859.13 KSA00707.1 - 0.19 11.6 0.0 0.28 11.0 0.0 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold DDE_1 PF03184.19 KSA00708.1 - 1.8e-28 99.3 9.0 5.6e-28 97.8 6.8 2.8 2 1 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KSA00708.1 - 1.3e-16 60.3 1.1 1.1e-15 57.4 0.3 2.6 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_ABP1_N PF18107.1 KSA00708.1 - 1.4e-05 24.7 0.1 5.5e-05 22.8 0.1 2.0 1 0 0 1 1 1 1 Fission yeast centromere protein N-terminal domain PEP-utilisers_N PF05524.13 KSA00709.1 - 0.032 14.4 0.1 0.032 14.4 0.1 1.1 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal Pet100 PF09803.9 KSA00709.1 - 0.097 13.2 0.1 0.11 13.1 0.1 1.1 1 0 0 1 1 1 0 Pet100 DUF1192 PF06698.11 KSA00709.1 - 0.1 12.7 4.1 0.14 12.2 4.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) Cwf_Cwc_15 PF04889.12 KSA00709.1 - 0.11 12.2 3.7 0.12 12.1 3.7 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF846 PF05832.12 KSA00710.1 - 4.9e-53 178.9 14.1 6.1e-53 178.6 14.1 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) DUF3589 PF12141.8 KSA00711.1 - 3e-89 299.9 0.0 1.5e-86 291.0 0.0 2.1 1 1 0 1 1 1 1 Beta-mannosyltransferases Clathrin PF00637.20 KSA00712.1 - 1.3e-30 106.1 4.6 3.7e-30 104.7 3.5 2.4 2 0 0 2 2 2 1 Region in Clathrin and VPS WD40 PF00400.32 KSA00712.1 - 0.0019 19.0 0.1 0.0071 17.2 0.1 2.1 1 0 0 1 1 1 1 WD domain, G-beta repeat TPR_7 PF13176.6 KSA00712.1 - 0.029 14.4 0.0 11 6.3 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Vps39_1 PF10366.9 KSA00712.1 - 0.037 14.3 0.3 0.037 14.3 0.3 2.3 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 Tfb5 PF06331.12 KSA00713.1 - 8.5e-28 96.1 0.7 9.3e-28 96.0 0.7 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 Binary_toxB_3 PF17476.2 KSA00713.1 - 0.003 17.7 0.1 0.0036 17.5 0.1 1.1 1 0 0 1 1 1 1 Clostridial binary toxin B/anthrax toxin PA domain 3 Sec34 PF04136.15 KSA00714.1 - 1.6e-42 144.9 8.9 1.6e-42 144.9 8.9 2.8 3 0 0 3 3 3 1 Sec34-like family Baculo_p24 PF05073.12 KSA00714.1 - 0.001 18.9 4.5 0.001 18.9 4.5 2.9 3 0 0 3 3 3 1 Baculovirus P24 capsid protein TIP120 PF08623.10 KSA00714.1 - 0.03 14.1 3.9 0.18 11.5 0.7 2.8 2 0 0 2 2 2 0 TATA-binding protein interacting (TIP20) DUF3685 PF12452.8 KSA00714.1 - 0.11 12.1 5.5 0.041 13.6 1.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3685) Sec20 PF03908.13 KSA00714.1 - 0.36 10.8 3.1 2.5 8.1 3.1 2.6 1 0 0 1 1 1 0 Sec20 zf-primase PF09329.11 KSA00715.1 - 7.3e-15 54.5 2.6 1.6e-14 53.4 2.6 1.6 1 0 0 1 1 1 1 Primase zinc finger tRNA_anti-codon PF01336.25 KSA00715.1 - 2.7e-05 24.1 0.0 7.9e-05 22.6 0.0 1.8 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain REPA_OB_2 PF16900.5 KSA00715.1 - 0.025 14.5 0.3 0.13 12.2 0.0 2.4 2 0 0 2 2 2 0 Replication protein A OB domain DUF1824 PF08854.10 KSA00715.1 - 0.66 9.9 3.6 5.8 6.9 0.0 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1824) p450 PF00067.22 KSA00716.1 - 8.3e-62 209.4 0.1 1.1e-61 209.1 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 UPF0160 PF03690.13 KSA00717.1 - 3.1e-132 441.0 0.0 3.5e-132 440.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) E1-E2_ATPase PF00122.20 KSA00718.1 - 5.1e-32 110.8 13.8 8.7e-30 103.6 0.1 4.4 5 1 1 6 6 6 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 KSA00718.1 - 1.5e-24 86.7 5.7 1.5e-24 86.7 5.7 3.2 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KSA00718.1 - 6.9e-19 69.0 0.0 2.2e-17 64.1 0.0 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KSA00718.1 - 2.2e-18 66.1 0.0 5.4e-18 64.9 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KSA00718.1 - 5.3e-15 54.9 0.0 1.3e-14 53.6 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KSA00718.1 - 0.00017 21.4 0.7 0.001 18.9 0.8 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Sugar_tr PF00083.24 KSA00719.1 - 2.8e-101 339.6 31.3 3.5e-101 339.3 31.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KSA00719.1 - 1.6e-21 76.6 35.0 1.4e-20 73.5 29.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_3_2 PF04550.12 KSA00719.1 - 0.15 12.6 1.3 0.27 11.8 0.3 2.0 2 0 0 2 2 2 0 Phage holin family 2 Pkinase PF00069.25 KSA00720.1 - 2e-36 125.7 3.1 7.1e-24 84.6 0.7 3.0 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KSA00720.1 - 2.4e-15 56.5 0.1 1e-13 51.2 0.0 2.7 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KSA00720.1 - 0.0022 17.3 0.3 1.9 7.7 0.1 2.8 2 1 0 2 2 2 2 Kinase-like FAM83 PF07894.12 KSA00720.1 - 0.043 13.4 0.1 0.066 12.7 0.1 1.3 1 0 0 1 1 1 0 FAM83 A-H Choline_kinase PF01633.20 KSA00720.1 - 0.045 13.3 0.1 0.083 12.5 0.1 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase GalKase_gal_bdg PF10509.9 KSA00721.1 - 3.3e-23 81.0 0.0 7.9e-23 79.8 0.0 1.7 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 KSA00721.1 - 1e-16 60.9 1.3 2.8e-16 59.5 1.3 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KSA00721.1 - 4.8e-13 49.3 0.0 1.2e-12 48.1 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal Aldose_epim PF01263.20 KSA00722.1 - 2.3e-72 243.8 2.7 3.1e-72 243.4 2.7 1.2 1 0 0 1 1 1 1 Aldose 1-epimerase GDP_Man_Dehyd PF16363.5 KSA00722.1 - 2.1e-54 185.2 0.0 3.1e-54 184.6 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KSA00722.1 - 2.2e-50 171.4 0.0 6.5e-50 169.8 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KSA00722.1 - 1.1e-18 67.3 0.0 3.3e-18 65.7 0.0 1.7 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KSA00722.1 - 1.1e-17 64.1 0.0 3.7e-16 59.1 0.0 2.2 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KSA00722.1 - 7.8e-11 41.6 0.0 1.2e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 KSA00722.1 - 7.8e-09 35.7 0.0 1.4e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KSA00722.1 - 1.4e-06 28.3 0.0 2.5e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 KSA00722.1 - 2.6e-06 27.0 0.0 4.4e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.12 KSA00722.1 - 2.8e-06 26.7 0.0 0.00018 20.8 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.13 KSA00722.1 - 0.0002 21.0 0.0 0.00039 20.1 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family UDPG_MGDP_dh_N PF03721.14 KSA00722.1 - 0.083 12.5 0.1 0.17 11.4 0.1 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Isochorismatase PF00857.20 KSA00722.1 - 0.1 12.8 0.1 5 7.3 0.0 2.7 3 0 0 3 3 3 0 Isochorismatase family Glyco_hydro_47 PF01532.20 KSA00723.1 - 2.6e-169 564.0 0.0 3e-169 563.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Zn_clus PF00172.18 KSA00724.1 - 0.0014 18.7 12.7 0.0024 18.0 12.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_M9_N PF08453.10 KSA00724.1 - 0.0051 16.5 0.8 1.3 8.8 0.0 2.8 2 0 0 2 2 2 2 Peptidase family M9 N-terminal DUF1003 PF06210.11 KSA00724.1 - 4.1 7.6 5.2 12 6.1 5.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) Cyt-b5 PF00173.28 KSA00725.1 - 1.3e-11 44.4 0.1 3.1e-11 43.3 0.1 1.7 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Cys_Met_Meta_PP PF01053.20 KSA00726.1 - 9.3e-36 123.2 0.0 1.3e-35 122.7 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KSA00726.1 - 1.7e-06 27.5 0.1 1.3e-05 24.5 0.0 2.1 2 0 0 2 2 2 1 Aminotransferase class I and II HMG-CoA_red PF00368.18 KSA00727.1 - 9.6e-144 478.9 0.2 1.4e-143 478.3 0.2 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.6 KSA00727.1 - 1.4e-11 44.5 4.5 1.9e-10 40.8 4.5 2.4 1 1 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.8 KSA00727.1 - 1.2e-09 38.2 6.4 1.2e-09 38.2 6.4 1.9 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 KSA00727.1 - 0.0056 14.8 7.7 0.0084 14.2 7.7 1.1 1 0 0 1 1 1 1 Patched family FKBP_C PF00254.28 KSA00728.1 - 4.9e-26 90.9 2.3 6.1e-26 90.6 0.1 2.3 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 KSA00728.1 - 4.6e-24 85.0 0.3 4.6e-24 85.0 0.3 2.4 2 1 0 2 2 2 1 Nucleoplasmin-like domain SDA1 PF05285.12 KSA00728.1 - 4.9 6.5 51.2 1.4 8.3 23.6 2.3 2 0 0 2 2 2 0 SDA1 Rtf2 PF04641.12 KSA00728.1 - 7.1 5.9 27.2 0.93 8.8 1.8 2.4 2 0 0 2 2 2 0 Rtf2 RING-finger Ribosomal_L6e PF01159.19 KSA00729.1 - 1.8e-39 134.7 0.8 2.5e-39 134.3 0.8 1.2 1 0 0 1 1 1 1 Ribosomal protein L6e C2 PF00168.30 KSA00730.1 - 1.2e-60 202.2 3.0 1.1e-17 64.2 0.0 6.1 6 0 0 6 6 6 5 C2 domain NT-C2 PF10358.9 KSA00730.1 - 0.0048 16.6 0.7 6 6.6 0.1 4.7 4 2 1 5 5 5 1 N-terminal C2 in EEIG1 and EHBP1 proteins DUF4497 PF14924.6 KSA00730.1 - 0.049 14.1 0.0 2 8.9 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4497) Ribosomal_S3Ae PF01015.18 KSA00731.1 - 7.5e-85 283.6 5.3 9e-85 283.3 5.3 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.16 KSA00731.1 - 0.12 12.0 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Lambda_CIII PF02061.16 KSA00731.1 - 0.25 11.4 0.5 1.5 8.9 0.1 2.3 2 0 0 2 2 2 0 Lambda Phage CIII Ras PF00071.22 KSA00732.1 - 1.9e-08 34.0 0.1 2.2e-08 33.8 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KSA00732.1 - 0.052 13.8 0.0 0.091 13.0 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase ATP-grasp_6 PF18419.1 KSA00732.1 - 0.086 12.5 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp-like domain GTP_EFTU PF00009.27 KSA00732.1 - 0.11 12.0 0.0 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA PF00004.29 KSA00734.1 - 3.3e-18 66.4 0.2 9.6e-18 64.9 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_10 PF17872.1 KSA00734.1 - 2.5e-15 56.4 0.6 1.1e-14 54.4 0.6 2.1 1 0 0 1 1 1 1 AAA lid domain AAA_16 PF13191.6 KSA00734.1 - 1.2e-08 35.5 0.0 4.6e-07 30.4 0.0 2.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KSA00734.1 - 5e-06 26.8 0.0 1.8e-05 25.0 0.0 2.0 2 0 0 2 2 1 1 AAA domain BAH PF01426.18 KSA00734.1 - 0.00011 22.0 0.5 0.00032 20.5 0.1 2.0 2 0 0 2 2 2 1 BAH domain AAA_19 PF13245.6 KSA00734.1 - 0.00078 19.8 0.1 0.0028 18.0 0.0 2.0 2 1 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 KSA00734.1 - 0.0011 18.9 6.8 0.0013 18.7 0.1 3.6 2 2 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_18 PF13238.6 KSA00734.1 - 0.054 14.0 0.0 0.3 11.6 0.0 2.4 2 0 0 2 2 1 0 AAA domain NTPase_1 PF03266.15 KSA00734.1 - 0.07 13.0 0.3 0.55 10.1 0.0 2.4 2 0 0 2 2 2 0 NTPase RNA_helicase PF00910.22 KSA00734.1 - 0.092 13.1 0.1 1.9 8.9 0.0 2.8 3 0 0 3 3 2 0 RNA helicase AAA_assoc_2 PF16193.5 KSA00734.1 - 0.12 12.7 0.0 0.58 10.5 0.0 2.2 1 0 0 1 1 1 0 AAA C-terminal domain CT47 PF15623.6 KSA00734.1 - 4.2 7.1 12.0 10 5.8 11.4 1.8 2 0 0 2 2 2 0 Cancer/testis gene family 47 CDC45 PF02724.14 KSA00734.1 - 8.7 4.5 13.5 13 3.9 13.5 1.2 1 0 0 1 1 1 0 CDC45-like protein WGG PF10273.9 KSA00735.1 - 1.6e-23 83.2 0.4 2.9e-23 82.3 0.4 1.5 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 DUF599 PF04654.12 KSA00735.1 - 0.2 11.0 0.0 0.29 10.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF599 Hid1 PF12722.7 KSA00736.1 - 1.7e-257 856.7 13.9 2e-257 856.5 13.9 1.0 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 KSA00736.1 - 5.8e-33 114.2 6.9 5.8e-33 114.2 6.9 1.5 2 0 0 2 2 2 1 Dyggve-Melchior-Clausen syndrome protein Voldacs PF03517.13 KSA00737.1 - 3.7e-13 49.8 0.4 9.3e-13 48.5 0.4 1.7 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling Metallophos PF00149.28 KSA00738.1 - 3.8e-36 125.5 0.0 6.6e-36 124.7 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Phage_Orf51 PF06194.11 KSA00738.1 - 0.13 12.3 0.0 0.43 10.6 0.0 1.8 2 0 0 2 2 2 0 Phage Conserved Open Reading Frame 51 Orn_Arg_deC_N PF02784.16 KSA00739.1 - 3e-71 239.7 0.0 4.2e-71 239.2 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 KSA00739.1 - 2.8e-17 62.7 0.0 5.4e-17 61.8 0.0 1.7 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Ala_racemase_N PF01168.20 KSA00739.1 - 0.022 14.4 0.0 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 Alanine racemase, N-terminal domain VHS PF00790.19 KSA00740.1 - 2.2e-29 102.1 0.1 6e-29 100.7 0.1 1.8 1 0 0 1 1 1 1 VHS domain FYVE PF01363.21 KSA00740.1 - 1e-17 64.0 3.6 2e-17 63.1 3.6 1.5 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.20 KSA00740.1 - 1e-05 25.1 19.1 0.00052 19.8 3.7 3.3 3 0 0 3 3 3 2 Ubiquitin interaction motif FYVE_2 PF02318.16 KSA00740.1 - 0.011 15.9 2.2 0.011 15.9 2.2 2.4 2 0 0 2 2 2 0 FYVE-type zinc finger GAT PF03127.14 KSA00740.1 - 0.027 14.8 1.6 0.065 13.6 1.6 1.7 1 0 0 1 1 1 0 GAT domain Hrs_helical PF12210.8 KSA00740.1 - 0.043 14.4 0.2 0.16 12.5 0.2 2.0 1 0 0 1 1 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate zf-AN1 PF01428.16 KSA00740.1 - 0.54 10.5 7.4 1.1 9.4 7.4 1.6 1 0 0 1 1 1 0 AN1-like Zinc finger zf-RING_2 PF13639.6 KSA00740.1 - 6.4 7.2 8.6 2.2 8.7 5.1 1.9 2 0 0 2 2 2 0 Ring finger domain Rot1 PF10681.9 KSA00741.1 - 1.8e-95 318.4 0.3 2.1e-95 318.2 0.3 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal Baseplate_J PF04865.14 KSA00741.1 - 0.056 12.6 0.0 5 6.2 0.0 2.1 2 0 0 2 2 2 0 Baseplate J-like protein Pre-PUA PF17832.1 KSA00741.1 - 0.48 11.2 2.3 1.8 9.3 0.9 2.1 1 1 1 2 2 2 0 Pre-PUA-like domain Cyclin_N PF00134.23 KSA00742.1 - 7.1e-22 77.5 0.0 1.6e-21 76.3 0.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain BBP1_C PF15272.6 KSA00743.1 - 4.7e-07 29.8 15.9 4.7e-07 29.8 15.9 3.1 2 1 1 3 3 3 1 Spindle pole body component BBP1, C-terminal SPK PF04435.18 KSA00743.1 - 0.049 14.0 3.0 0.16 12.4 3.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF545) GPS2_interact PF15784.5 KSA00743.1 - 1.1 9.8 4.8 0.36 11.3 0.9 2.2 2 0 0 2 2 2 0 G-protein pathway suppressor 2-interacting domain LUC7 PF03194.15 KSA00743.1 - 1.3 8.7 8.1 0.066 12.9 2.5 1.7 2 0 0 2 2 2 0 LUC7 N_terminus Alpha_GJ PF03229.13 KSA00744.1 - 0.84 10.2 15.8 1.1 9.8 15.8 1.2 1 0 0 1 1 1 0 Alphavirus glycoprotein J MatE PF01554.18 KSA00745.1 - 6.4e-63 211.2 24.1 1.5e-36 125.5 8.4 2.4 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 KSA00745.1 - 1.3e-06 28.5 4.9 1.3e-06 28.5 4.9 3.9 4 0 0 4 4 4 2 Polysaccharide biosynthesis C-terminal domain ERG2_Sigma1R PF04622.12 KSA00746.1 - 1.8e-90 301.9 0.1 2.1e-90 301.7 0.1 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein PCI PF01399.27 KSA00747.1 - 1.7e-06 28.5 0.6 6e-06 26.7 0.1 2.2 2 1 0 2 2 2 1 PCI domain DUF1599 PF07659.11 KSA00747.1 - 0.28 11.7 1.9 22 5.6 0.0 3.4 4 0 0 4 4 4 0 Nucleotide modification associated domain 1 Aldo_ket_red PF00248.21 KSA00748.1 - 7.3e-46 156.7 0.2 4.5e-45 154.1 0.2 1.8 1 1 0 1 1 1 1 Aldo/keto reductase family Adap_comp_sub PF00928.21 KSA00749.1 - 1e-16 61.1 0.1 2.1e-16 60.1 0.1 1.5 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KSA00749.1 - 1.4e-08 34.7 2.8 2.1e-08 34.2 0.6 2.1 2 0 0 2 2 2 1 Clathrin adaptor complex small chain Rib_recp_KP_reg PF05104.12 KSA00749.1 - 0.29 12.2 7.4 0.5 11.4 7.4 1.3 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region PDEase_II PF02112.15 KSA00750.1 - 3.3e-73 246.7 7.7 4.1e-73 246.4 7.7 1.0 1 0 0 1 1 1 1 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.7 KSA00750.1 - 1.5e-08 34.4 0.0 2.5e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Bac_RepA_C PF18008.1 KSA00750.1 - 0.081 13.3 0.8 1.4 9.3 0.0 2.6 2 0 0 2 2 2 0 Replication initiator protein A C-terminal domain Proteasome PF00227.26 KSA00751.1 - 2e-27 95.9 0.0 2.5e-27 95.6 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit S36_mt PF10937.8 KSA00752.1 - 1.2e-19 72.0 5.0 4.3e-09 38.0 0.1 2.0 1 1 1 2 2 2 2 Ribosomal protein S36, mitochondrial ADH_zinc_N PF00107.26 KSA00754.1 - 1.7e-09 37.7 0.1 3.1e-09 36.9 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KSA00754.1 - 1.8e-07 31.0 0.5 9.5e-07 28.7 0.2 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain DUF410 PF04190.13 KSA00755.1 - 1.1e-68 231.8 2.3 1.3e-68 231.5 2.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF410) RPN6_N PF18055.1 KSA00755.1 - 0.021 15.2 0.1 3.5 8.0 0.0 2.6 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN6 N-terminal domain PaREP1 PF05942.11 KSA00755.1 - 0.051 13.5 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Archaeal PaREP1/PaREP8 family NUDIX PF00293.28 KSA00756.1 - 9.2e-13 48.4 0.0 1.2e-12 48.0 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain DEC1 PF15859.5 KSA00756.1 - 0.036 14.1 0.0 0.2 11.7 0.0 2.2 2 1 0 2 2 2 0 Deleted in esophageal cancer 1 family EF-hand_6 PF13405.6 KSA00757.1 - 2.1e-07 30.3 0.5 0.026 14.4 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 KSA00757.1 - 3.9e-05 24.0 0.6 0.00012 22.5 0.4 1.9 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KSA00757.1 - 6e-05 22.3 0.7 0.00048 19.5 0.0 2.3 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 KSA00757.1 - 0.0036 17.1 0.2 0.57 10.1 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KSA00757.1 - 0.012 15.1 0.1 0.028 13.9 0.1 1.7 1 0 0 1 1 1 0 EF hand ACBP PF00887.19 KSA00757.1 - 0.082 13.1 0.1 0.6 10.4 0.0 2.2 1 1 1 2 2 2 0 Acyl CoA binding protein CX9C PF16860.5 KSA00758.1 - 1.8e-24 85.4 10.6 2.2e-18 66.0 1.2 2.1 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, CHCH PF06747.13 KSA00758.1 - 0.00017 21.6 11.6 0.0053 16.9 3.1 3.0 2 1 0 2 2 2 2 CHCH domain COX6B PF02297.17 KSA00758.1 - 0.00092 19.4 6.4 0.014 15.6 0.6 2.1 1 1 1 2 2 2 2 Cytochrome oxidase c subunit VIb MTCP1 PF08991.10 KSA00758.1 - 0.055 13.7 1.6 0.055 13.7 1.6 2.1 2 0 0 2 2 2 0 Mature-T-Cell Proliferation I type NDUF_B7 PF05676.13 KSA00758.1 - 0.17 11.6 6.1 2.5 7.9 0.6 2.2 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) DB PF01682.19 KSA00758.1 - 0.34 11.3 7.9 0.8 10.0 8.1 1.5 1 1 0 1 1 1 0 DB module GCK PF07802.11 KSA00758.1 - 1.1 9.8 4.9 26 5.3 0.2 2.3 1 1 1 2 2 2 0 GCK domain COX17 PF05051.13 KSA00758.1 - 1.1 9.6 8.7 3 8.3 2.1 2.8 1 1 1 3 3 3 0 Cytochrome C oxidase copper chaperone (COX17) DUF3128 PF11326.8 KSA00758.1 - 2.6 8.5 7.7 6.2 7.3 0.7 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF3128) Peptidase_S24 PF00717.23 KSA00759.1 - 1.4e-09 37.8 0.3 4.4e-09 36.2 0.3 1.8 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 KSA00759.1 - 1.4e-05 24.9 0.0 0.016 15.0 0.0 2.8 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 LicD PF04991.13 KSA00760.1 - 3e-28 99.5 5.9 3e-28 99.5 5.9 2.5 2 1 0 2 2 2 1 LicD family DUF5114 PF17141.4 KSA00760.1 - 0.16 12.5 0.3 0.34 11.5 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5114) Folliculin PF11704.8 KSA00761.1 - 2e-47 161.5 0.2 3e-47 160.9 0.2 1.3 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport Imm42 PF15593.6 KSA00761.1 - 0.19 12.2 2.4 0.35 11.4 0.8 2.0 1 1 1 2 2 2 0 Immunity protein 42 Atg14 PF10186.9 KSA00762.1 - 0.0026 16.9 9.9 0.0085 15.2 0.1 2.2 2 0 0 2 2 2 2 Vacuolar sorting 38 and autophagy-related subunit 14 APG6 PF04111.12 KSA00762.1 - 0.0041 17.1 0.0 0.0098 15.9 0.0 1.6 1 0 0 1 1 1 1 Apg6 BARA domain DUF948 PF06103.11 KSA00762.1 - 0.8 10.0 2.9 0.95 9.8 0.1 2.5 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Fib_alpha PF08702.10 KSA00762.1 - 4.8 7.4 11.2 1.4 9.1 6.1 2.6 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF1631 PF07793.11 KSA00763.1 - 0.02 13.4 0.9 0.021 13.3 0.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) SpoIIIAH PF12685.7 KSA00763.1 - 0.7 9.7 10.9 0.87 9.4 10.9 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein DUF1180 PF06679.12 KSA00763.1 - 0.87 10.0 8.0 1 9.8 8.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Presenilin PF01080.17 KSA00763.1 - 1.2 7.8 5.5 1.3 7.7 5.5 1.0 1 0 0 1 1 1 0 Presenilin RAP1 PF07218.11 KSA00763.1 - 1.5 7.0 24.3 1.6 6.9 24.3 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Macoilin PF09726.9 KSA00763.1 - 1.5 7.3 15.4 1.5 7.2 15.4 1.0 1 0 0 1 1 1 0 Macoilin family Miga PF10265.9 KSA00763.1 - 1.9 7.4 11.3 2 7.3 11.3 1.0 1 0 0 1 1 1 0 Mitoguardin Peroxin-3 PF04882.12 KSA00763.1 - 2.7 6.9 9.0 3.1 6.7 9.0 1.0 1 0 0 1 1 1 0 Peroxin-3 DUF572 PF04502.13 KSA00763.1 - 3.5 7.2 8.8 3.9 7.0 8.8 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) Apt1 PF10351.9 KSA00763.1 - 3.6 6.4 13.6 3.9 6.2 13.6 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain CCDC24 PF15669.5 KSA00763.1 - 4.3 7.2 8.7 5.5 6.8 8.7 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family ANAPC1 PF12859.7 KSA00763.1 - 4.7 7.8 8.2 5.6 7.5 8.2 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 1 Menin PF05053.13 KSA00763.1 - 5.2 5.3 8.8 5.5 5.2 8.8 1.0 1 0 0 1 1 1 0 Menin CCDC106 PF15794.5 KSA00763.1 - 10 5.8 13.3 12 5.5 13.3 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 WD40 PF00400.32 KSA00764.1 - 7e-57 188.1 17.6 7.7e-10 39.2 0.1 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 KSA00764.1 - 1.7e-47 160.9 0.8 3.5e-47 159.9 0.8 1.5 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 KSA00764.1 - 3.4e-15 56.1 0.0 0.19 12.1 0.0 6.4 2 1 5 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 KSA00764.1 - 1.6e-06 27.8 0.1 4.1e-06 26.6 0.1 1.7 1 0 0 1 1 1 1 LisH WD40_like PF17005.5 KSA00764.1 - 7.6e-06 25.5 0.1 0.21 10.9 0.0 3.6 4 0 0 4 4 4 2 WD40-like domain eIF2A PF08662.11 KSA00764.1 - 9.9e-06 25.6 0.0 0.0012 18.7 0.0 2.7 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KSA00764.1 - 1.7e-05 23.9 0.0 7 5.5 0.0 4.6 2 2 3 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KSA00764.1 - 3.2e-05 22.8 1.2 0.047 12.3 0.0 3.6 2 2 1 4 4 4 2 Nucleoporin Nup120/160 ELYS-bb PF16687.5 KSA00764.1 - 0.12 11.0 0.0 0.24 10.0 0.0 1.4 1 0 0 1 1 1 0 beta-propeller of ELYS nucleoporin TFIIA PF03153.13 KSA00764.1 - 2.3 8.1 11.9 4.9 7.0 11.9 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GPI2 PF06432.11 KSA00765.1 - 4.8e-84 282.1 20.1 5.6e-84 281.9 20.1 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase DUF4149 PF13664.6 KSA00765.1 - 3.1 8.2 13.8 1.7 9.0 0.2 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4149) UPF0139 PF03669.13 KSA00765.1 - 10 6.1 6.6 0.86 9.5 0.5 2.4 3 1 0 3 3 3 0 Uncharacterised protein family (UPF0139) DUF5315 PF17242.2 KSA00766.1 - 1.1e-19 70.0 0.2 2.3e-19 69.0 0.2 1.6 1 0 0 1 1 1 1 Disordered region of unknown function (DUF5315) DUF3543 PF12063.8 KSA00766.1 - 0.007 15.8 1.1 0.0096 15.3 0.7 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF3543) NPV_P10 PF05531.12 KSA00766.1 - 0.086 13.3 3.3 5.5 7.5 0.1 3.1 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Prominin PF05478.11 KSA00766.1 - 7.9 4.3 11.2 1.7 6.5 6.9 1.8 1 1 0 2 2 2 0 Prominin Hexokinase_2 PF03727.16 KSA00767.1 - 7.3e-80 267.8 0.0 9.8e-80 267.4 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KSA00767.1 - 2.5e-72 243.0 0.0 4.3e-72 242.2 0.0 1.4 1 0 0 1 1 1 1 Hexokinase YcgL PF05166.13 KSA00767.1 - 0.17 12.3 0.1 2.3 8.6 0.0 2.3 2 0 0 2 2 2 0 YcgL domain TOM13 PF08219.11 KSA00768.1 - 3.3e-28 97.5 0.0 5.5e-28 96.8 0.0 1.5 1 0 0 1 1 1 1 Outer membrane protein TOM13 MIF4G_like PF09088.11 KSA00768.1 - 0.05 13.4 0.0 0.064 13.0 0.0 1.1 1 0 0 1 1 1 0 MIF4G like Lyase_1 PF00206.20 KSA00769.1 - 2.2e-117 391.9 0.0 2.8e-117 391.6 0.0 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 KSA00769.1 - 4.7e-25 87.8 0.0 1.5e-24 86.1 0.0 2.0 2 0 0 2 2 2 1 Fumarase C C-terminus Rpr2 PF04032.16 KSA00770.1 - 3.9e-23 81.6 0.6 5.1e-23 81.2 0.6 1.2 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain ADD_ATRX PF17981.1 KSA00770.1 - 0.004 17.0 0.3 0.1 12.5 0.0 2.2 2 0 0 2 2 2 1 Cysteine Rich ADD domain DUF1192 PF06698.11 KSA00771.1 - 0.00035 20.6 1.4 0.00046 20.2 1.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1192) FtsZ_C PF12327.8 KSA00771.1 - 0.096 13.0 0.3 0.11 12.8 0.3 1.1 1 0 0 1 1 1 0 FtsZ family, C-terminal domain XPG_N PF00752.17 KSA00772.1 - 7.5e-34 116.2 0.0 1.5e-33 115.3 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 KSA00772.1 - 1.4e-28 99.1 0.1 2.9e-28 98.1 0.1 1.6 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.20 KSA00772.1 - 1.3e-05 25.7 0.0 4.1e-05 24.1 0.0 1.8 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold HHH_2 PF12826.7 KSA00772.1 - 0.026 14.6 0.0 0.069 13.3 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif Nucleoporin2 PF04096.14 KSA00773.1 - 9.6e-44 149.1 0.0 1.5e-43 148.5 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 KSA00773.1 - 1.5e-32 112.3 359.7 5e-13 49.7 34.4 11.3 2 2 8 10 10 10 6 Nucleoporin FG repeat region AP_endonuc_2 PF01261.24 KSA00774.1 - 6.4e-35 120.5 0.0 9e-35 120.0 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Telomere_reg-2 PF10193.9 KSA00776.1 - 2.7e-26 92.1 0.1 1.1e-25 90.2 0.1 2.1 1 0 0 1 1 1 1 Telomere length regulation protein DUF966 PF06136.13 KSA00778.1 - 0.25 11.1 7.9 0.28 10.8 7.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) SLC12 PF03522.15 KSA00778.1 - 1.4 7.9 6.9 1.7 7.6 6.9 1.1 1 0 0 1 1 1 0 Solute carrier family 12 GREB1 PF15782.5 KSA00778.1 - 1.7 5.6 7.9 2 5.5 7.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer VirE2 PF07229.12 KSA00778.1 - 1.9 7.1 8.1 2.4 6.7 8.1 1.1 1 0 0 1 1 1 0 VirE2 DUF1387 PF07139.11 KSA00778.1 - 2.1 8.0 11.7 2.7 7.6 11.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Strabismus PF06638.11 KSA00778.1 - 2.1 6.9 8.6 2.6 6.6 8.6 1.2 1 0 0 1 1 1 0 Strabismus protein Toxin_10 PF05431.11 KSA00778.1 - 2.4 7.6 13.0 3 7.3 13.0 1.2 1 0 0 1 1 1 0 Insecticidal Crystal Toxin, P42 Macoilin PF09726.9 KSA00778.1 - 6.6 5.2 14.6 7.9 4.9 14.6 1.0 1 0 0 1 1 1 0 Macoilin family Utp14 PF04615.13 KSA00778.1 - 6.7 5.2 15.9 8 4.9 15.9 1.0 1 0 0 1 1 1 0 Utp14 protein PH_10 PF15411.6 KSA00779.1 - 0.027 14.7 0.1 0.5 10.6 0.0 3.0 2 1 1 3 3 3 0 Pleckstrin homology domain YmgB PF10798.8 KSA00779.1 - 0.086 12.7 0.0 0.36 10.7 0.0 2.0 1 0 0 1 1 1 0 Biofilm development protein YmgB/AriR zf-RING_2 PF13639.6 KSA00779.1 - 0.52 10.7 6.1 1.5 9.2 6.1 1.9 1 0 0 1 1 1 0 Ring finger domain PHD PF00628.29 KSA00779.1 - 0.94 9.4 6.3 2.1 8.3 6.3 1.6 1 0 0 1 1 1 0 PHD-finger zf-C3HC4 PF00097.25 KSA00779.1 - 6.2 6.8 10.9 19 5.2 10.9 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ribonuc_L-PSP PF01042.21 KSA00780.1 - 3.2e-23 82.0 0.0 3.8e-23 81.8 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP TFR_dimer PF04253.15 KSA00781.1 - 3.4e-24 85.3 0.1 8.1e-24 84.0 0.1 1.6 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 KSA00781.1 - 2.1e-22 79.8 0.0 3.4e-22 79.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KSA00781.1 - 4.5e-12 45.8 0.1 1.1e-11 44.6 0.1 1.6 1 0 0 1 1 1 1 PA domain Nicastrin PF05450.15 KSA00781.1 - 0.11 11.9 0.0 0.26 10.7 0.0 1.5 1 0 0 1 1 1 0 Nicastrin MFS_1 PF07690.16 KSA00783.1 - 4.4e-32 111.4 16.6 7.7e-18 64.5 0.3 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KSA00783.1 - 2.4e-09 36.3 30.3 7.6e-07 28.0 7.6 3.2 2 1 1 3 3 3 2 MFS/sugar transport protein Sugar_tr PF00083.24 KSA00783.1 - 5.8e-09 35.3 13.0 9.1e-09 34.7 13.0 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.7 KSA00783.1 - 7.9e-09 34.8 18.5 7.8e-06 25.0 4.8 2.1 2 0 0 2 2 2 2 MFS_1 like family ATG22 PF11700.8 KSA00783.1 - 0.00032 19.5 2.8 0.00032 19.5 2.8 3.6 1 1 2 3 3 3 2 Vacuole effluxer Atg22 like DUF4050 PF13259.6 KSA00783.1 - 0.062 13.6 0.3 0.096 13.0 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) PBP1_TM PF14812.6 KSA00783.1 - 0.13 12.6 0.1 0.22 11.9 0.1 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DciA PF05258.12 KSA00783.1 - 0.18 12.2 0.0 0.32 11.4 0.0 1.4 1 0 0 1 1 1 0 Dna[CI] antecedent, DciA OAD_gamma PF04277.13 KSA00783.1 - 1.4 9.5 0.0 1.4 9.5 0.0 3.0 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain DUF2264 PF10022.9 KSA00784.1 - 4.2e-119 397.8 0.0 5.3e-119 397.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) Sugar_tr PF00083.24 KSA00785.1 - 2.4e-62 211.3 24.5 2.8e-62 211.1 24.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KSA00785.1 - 2.6e-27 95.7 23.9 2.6e-27 95.7 23.9 2.1 1 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KSA00785.1 - 0.00031 19.3 1.2 0.00062 18.3 1.2 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) PUCC PF03209.15 KSA00785.1 - 0.044 12.8 4.7 0.049 12.6 0.3 2.1 2 0 0 2 2 2 0 PUCC protein Glyco_hydro_88 PF07470.13 KSA00786.1 - 0.00026 20.2 2.6 0.0017 17.5 2.6 2.2 1 1 0 1 1 1 1 Glycosyl Hydrolase Family 88 C5-epim_C PF06662.13 KSA00786.1 - 0.013 15.0 0.6 0.38 10.2 0.5 2.4 1 1 1 2 2 2 0 D-glucuronyl C5-epimerase C-terminus ADH_N PF08240.12 KSA00787.1 - 1.6e-26 92.4 4.2 2.6e-26 91.7 4.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KSA00787.1 - 1.4e-16 60.7 0.0 2.4e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KSA00787.1 - 7e-05 22.3 0.0 0.00011 21.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.6 KSA00787.1 - 0.0024 18.9 0.0 0.0039 18.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KSA00787.1 - 0.017 14.5 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DHDPS PF00701.22 KSA00788.1 - 7e-38 130.0 0.0 7.9e-38 129.8 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family DUF2264 PF10022.9 KSA00789.1 - 1.1e-11 44.5 1.1 1.4e-11 44.1 1.1 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) DUF3316 PF11777.8 KSA00789.1 - 0.27 11.3 0.2 0.27 11.3 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3316) Glyco_hydro_88 PF07470.13 KSA00790.1 - 4.9e-14 52.2 1.1 8.6e-11 41.5 0.3 2.2 2 0 0 2 2 2 2 Glycosyl Hydrolase Family 88 C5-epim_C PF06662.13 KSA00790.1 - 0.0079 15.7 1.0 0.17 11.4 0.2 2.5 1 1 0 2 2 2 1 D-glucuronyl C5-epimerase C-terminus Glyco_hydro_127 PF07944.12 KSA00790.1 - 0.033 12.7 0.1 0.052 12.0 0.1 1.3 1 0 0 1 1 1 0 Beta-L-arabinofuranosidase, GH127 adh_short_C2 PF13561.6 KSA00791.1 - 7e-47 159.9 0.0 8.5e-47 159.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KSA00791.1 - 1.8e-38 132.0 0.0 2.5e-38 131.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KSA00791.1 - 9.5e-10 38.7 0.0 4.7e-09 36.4 0.0 1.8 2 0 0 2 2 2 1 KR domain Fungal_trans PF04082.18 KSA00792.1 - 2.6e-18 66.0 6.1 7.4e-18 64.5 6.1 1.8 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 KSA00792.1 - 2.5e-06 27.6 0.7 2.5e-06 27.6 0.7 3.0 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.26 KSA00792.1 - 1.4e-05 25.3 16.9 0.0045 17.4 3.5 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KSA00792.1 - 0.00015 22.3 11.6 0.0028 18.4 2.2 3.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 KSA00792.1 - 0.00019 21.7 1.2 0.00071 19.9 1.2 2.1 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KSA00792.1 - 0.00023 21.4 3.2 0.0057 16.9 2.1 3.0 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding DUF1689 PF07954.11 KSA00792.1 - 0.053 13.9 0.2 0.17 12.3 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1689) zf-C2H2_6 PF13912.6 KSA00792.1 - 2.3 8.3 9.1 11 6.1 1.1 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger Cupin_2 PF07883.11 KSA00793.1 - 2.6e-08 33.4 0.0 6.6e-08 32.1 0.0 1.7 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 KSA00793.1 - 0.017 14.7 0.0 0.029 14.0 0.0 1.5 1 0 0 1 1 1 0 Cupin ADH_N PF08240.12 KSA00794.1 - 8.7e-27 93.2 3.6 8.7e-27 93.2 3.6 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KSA00794.1 - 5.6e-18 65.2 0.0 9e-18 64.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 KSA00794.1 - 0.00043 20.1 0.3 0.0014 18.5 0.0 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated AlaDh_PNT_C PF01262.21 KSA00794.1 - 0.035 13.4 0.0 0.061 12.6 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 KSA00795.1 - 3.2e-17 62.8 0.0 7.1e-17 61.7 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain ADC PF06314.11 KSA00795.1 - 3.6e-06 26.7 0.0 5.6e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) Pyr_redox_2 PF07992.14 KSA00795.1 - 6.9e-06 25.5 1.2 0.0031 16.8 0.1 2.2 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KSA00795.1 - 6.3e-05 23.1 0.2 0.0003 20.9 0.2 2.3 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KSA00795.1 - 0.00012 21.9 0.0 0.062 12.9 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KSA00795.1 - 0.00065 19.2 0.0 0.001 18.5 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KSA00795.1 - 0.00066 18.9 0.3 0.001 18.2 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 KSA00795.1 - 0.01 14.9 1.7 0.065 12.3 1.7 2.0 1 1 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.14 KSA00795.1 - 0.021 13.5 0.8 0.045 12.5 0.2 1.7 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox PF00070.27 KSA00795.1 - 0.032 14.8 1.3 0.88 10.2 0.1 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KSA00795.1 - 0.034 13.4 0.0 0.091 12.0 0.0 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Amino_oxidase PF01593.24 KSA00795.1 - 0.059 12.6 0.5 2.6 7.3 0.1 2.6 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase MFS_1 PF07690.16 KSA00796.1 - 2e-33 115.8 27.6 2.4e-33 115.5 18.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KSA00796.1 - 1.3e-15 57.3 4.1 1.3e-15 57.3 4.1 2.6 1 1 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.6 KSA00796.1 - 2.1e-06 26.6 8.0 2.1e-06 26.6 8.0 2.9 3 0 0 3 3 3 1 MFS/sugar transport protein TRI12 PF06609.13 KSA00796.1 - 0.0014 17.1 1.9 0.0025 16.3 1.9 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3493 PF11998.8 KSA00796.1 - 2 8.6 3.9 1.8 8.8 0.1 2.8 3 0 0 3 3 3 0 Low psii accumulation1 / Rep27 PepX_C PF08530.10 KSA00797.1 - 5.9e-43 147.4 0.1 9.1e-43 146.8 0.1 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S15 PF02129.18 KSA00797.1 - 2.7e-42 145.3 0.4 3.9e-42 144.7 0.4 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 KSA00797.1 - 0.011 15.1 0.0 0.018 14.3 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KSA00797.1 - 0.099 12.1 0.1 0.17 11.3 0.1 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KSA00797.1 - 0.11 12.2 0.1 0.23 11.1 0.1 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold FAD_binding_4 PF01565.23 KSA00799.1 - 9.7e-25 86.9 0.0 1.5e-24 86.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Aldedh PF00171.22 KSA00800.1 - 4.9e-161 536.3 0.0 5.5e-161 536.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KSA00800.1 - 0.0028 17.1 0.0 0.016 14.6 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) Aldedh PF00171.22 KSA00801.1 - 8.8e-105 350.9 0.2 9.8e-105 350.7 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Ski_Sno PF02437.17 KSA00802.1 - 0.11 12.3 0.1 0.3 10.8 0.0 1.7 2 0 0 2 2 2 0 SKI/SNO/DAC family LigB PF02900.18 KSA00804.1 - 2.2e-12 46.6 0.0 2.7e-12 46.3 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase HPD PF05044.12 KSA00804.1 - 0.016 15.1 0.0 0.024 14.5 0.0 1.2 1 0 0 1 1 1 0 Homeo-prospero domain PA PF02225.22 KSA00804.1 - 0.059 13.4 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 PA domain Aldo_ket_red PF00248.21 KSA00806.1 - 1.8e-64 217.8 0.0 2.1e-64 217.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Glyco_hydro_88 PF07470.13 KSA00807.1 - 1.7e-14 53.6 0.7 3.1e-12 46.3 0.4 2.1 2 0 0 2 2 2 2 Glycosyl Hydrolase Family 88 C5-epim_C PF06662.13 KSA00807.1 - 0.00015 21.3 2.9 0.0031 17.0 0.3 2.5 1 1 1 2 2 2 2 D-glucuronyl C5-epimerase C-terminus Glyco_hydro_76 PF03663.14 KSA00807.1 - 0.0014 18.3 0.8 0.0058 16.2 0.1 1.9 1 1 1 2 2 2 2 Glycosyl hydrolase family 76 GlcNAc_2-epim PF07221.11 KSA00807.1 - 0.0022 17.3 0.0 0.0057 15.9 0.0 1.6 1 1 1 2 2 2 1 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) LANC_like PF05147.13 KSA00807.1 - 0.022 13.3 0.1 0.13 10.8 0.1 2.0 2 1 0 2 2 2 0 Lanthionine synthetase C-like protein Glyco_hydro_127 PF07944.12 KSA00807.1 - 0.024 13.1 0.1 0.062 11.8 0.1 1.7 2 0 0 2 2 2 0 Beta-L-arabinofuranosidase, GH127 Aldo_ket_red PF00248.21 KSA00808.1 - 5.9e-17 61.8 0.0 6.9e-17 61.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family FAA_hydrolase PF01557.18 KSA00809.1 - 4.8e-53 180.0 0.0 7.4e-53 179.4 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Ribosomal_L16 PF00252.18 KSA00811.1 - 4.4e-41 140.0 0.1 5.5e-41 139.7 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e zf-C2H2_jaz PF12171.8 KSA00812.1 - 1.4e-09 38.0 3.3 2.7e-09 37.1 3.3 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KSA00812.1 - 0.005 17.2 0.1 0.0095 16.3 0.1 1.5 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KSA00812.1 - 0.089 13.7 0.2 0.21 12.5 0.2 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger zf-MYST PF17772.1 KSA00812.1 - 0.12 12.0 1.0 0.24 11.1 0.1 1.9 2 0 0 2 2 2 0 MYST family zinc finger domain zf-H2C2_2 PF13465.6 KSA00812.1 - 0.79 10.3 2.8 2.1 8.9 0.2 2.2 2 0 0 2 2 2 0 Zinc-finger double domain OTU PF02338.19 KSA00813.1 - 3.4e-07 30.8 0.0 8.2e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 KSA00813.1 - 3.2e-05 23.5 0.0 0.0019 17.7 0.0 2.4 2 0 0 2 2 2 2 Peptidase C65 Otubain eIF2A PF08662.11 KSA00814.1 - 1.6e-79 266.3 0.0 2.4e-79 265.7 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A CDV3 PF15359.6 KSA00814.1 - 0.03 14.8 0.9 0.03 14.8 0.9 2.4 1 1 1 2 2 2 0 Carnitine deficiency-associated protein 3 Glucan_synthase PF02364.15 KSA00815.1 - 0 1336.9 0.4 0 1334.0 0.0 2.0 2 0 0 2 2 2 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 KSA00815.1 - 5.2e-41 140.0 0.2 1.7e-40 138.3 0.2 2.0 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 DUF412 PF04217.13 KSA00815.1 - 0.05 13.5 0.7 0.14 12.0 0.7 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF412 DUF1751 PF08551.10 KSA00816.1 - 1.3e-28 99.5 4.1 2.9e-28 98.3 4.1 1.6 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 KSA00816.1 - 0.0004 20.4 6.6 0.00077 19.5 6.6 1.4 1 0 0 1 1 1 1 Rhomboid family Phageshock_PspG PF09583.10 KSA00816.1 - 0.017 15.4 0.5 0.017 15.4 0.5 3.1 3 0 0 3 3 3 0 Phage shock protein G (Phageshock_PspG) Glyco_transf_34 PF05637.12 KSA00817.1 - 2e-48 165.2 0.2 3e-48 164.6 0.2 1.2 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF3605 PF12239.8 KSA00817.1 - 0.18 12.2 4.1 1.7 9.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3605) DRMBL PF07522.14 KSA00818.1 - 2.1e-21 76.1 2.3 8.3e-21 74.2 2.3 2.1 1 1 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B PF00753.27 KSA00818.1 - 0.03 14.3 0.2 0.08 12.9 0.2 1.6 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily Arf PF00025.21 KSA00819.1 - 6.5e-48 162.5 0.5 7.3e-48 162.3 0.5 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KSA00819.1 - 8.8e-13 48.1 0.0 1e-12 47.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 KSA00819.1 - 3.1e-12 46.8 0.1 4.3e-12 46.3 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 KSA00819.1 - 4e-10 39.6 0.1 2.4e-08 33.7 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain G-alpha PF00503.20 KSA00819.1 - 5.5e-08 32.3 4.9 3.2e-07 29.8 1.1 2.4 1 1 1 2 2 2 1 G-protein alpha subunit Ras PF00071.22 KSA00819.1 - 1e-07 31.7 0.0 1.1e-07 31.6 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 KSA00819.1 - 2.7e-06 27.5 0.0 4.2e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KSA00819.1 - 0.00092 18.7 0.0 0.0011 18.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit cobW PF02492.19 KSA00819.1 - 0.0035 16.9 0.2 0.038 13.6 0.0 2.0 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain CdhD PF03599.16 KSA00819.1 - 0.017 13.9 0.0 0.022 13.5 0.0 1.1 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase delta subunit TIM21 PF08294.11 KSA00821.1 - 2.9e-46 156.9 0.0 3.7e-46 156.6 0.0 1.1 1 0 0 1 1 1 1 TIM21 CAP_N PF01213.19 KSA00821.1 - 0.051 13.0 0.4 0.074 12.5 0.4 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 KSA00821.1 - 0.056 13.5 0.4 0.1 12.7 0.4 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Androgen_recep PF02166.16 KSA00821.1 - 3.3 6.4 3.7 4.8 5.9 3.7 1.1 1 0 0 1 1 1 0 Androgen receptor Ribosomal_L26 PF16906.5 KSA00822.1 - 1.4e-26 92.7 1.2 1.6e-26 92.5 1.2 1.1 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 KSA00822.1 - 0.00026 20.8 0.1 0.00064 19.6 0.0 1.7 2 0 0 2 2 2 1 KOW motif 6PF2K PF01591.18 KSA00823.1 - 5.9e-61 205.6 0.2 8.9e-61 205.0 0.2 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KSA00823.1 - 4.1e-13 49.5 0.0 1.3e-11 44.6 0.0 2.2 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) KTI12 PF08433.10 KSA00823.1 - 0.026 14.0 0.0 0.083 12.3 0.0 1.7 1 1 0 1 1 1 0 Chromatin associated protein KTI12 AAA_18 PF13238.6 KSA00823.1 - 0.03 14.9 0.0 0.09 13.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KSA00823.1 - 0.031 14.5 0.0 0.069 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KSA00823.1 - 0.093 12.5 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Rhomboid_N PF12122.8 KSA00823.1 - 0.1 12.8 0.2 0.34 11.1 0.1 1.9 2 0 0 2 2 2 0 Cytoplasmic N-terminal domain of rhomboid serine protease Gon7 PF08738.10 KSA00824.1 - 3.9e-35 120.2 0.4 4.6e-35 120.0 0.4 1.0 1 0 0 1 1 1 1 Gon7 family Prefoldin_2 PF01920.20 KSA00825.1 - 5e-10 39.3 6.2 6.6e-10 38.9 6.2 1.1 1 0 0 1 1 1 1 Prefoldin subunit Baculo_PEP_C PF04513.12 KSA00825.1 - 0.017 15.2 1.5 0.017 15.2 1.5 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spore_II_R PF09551.10 KSA00825.1 - 0.089 13.3 1.6 0.14 12.7 1.2 1.5 1 1 0 1 1 1 0 Stage II sporulation protein R (spore_II_R) DUF1664 PF07889.12 KSA00825.1 - 0.24 11.4 4.8 1.3 9.1 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) ATP12 PF07542.11 KSA00826.1 - 2.3e-31 108.5 0.0 3.6e-31 107.9 0.0 1.3 1 0 0 1 1 1 1 ATP12 chaperone protein SF3A3 PF16837.5 KSA00826.1 - 0.55 10.8 3.9 0.23 12.0 0.8 2.0 2 0 0 2 2 2 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 SMK-1 PF04802.15 KSA00827.1 - 5.6e-57 192.7 17.1 2.3e-55 187.4 12.6 2.8 2 1 1 3 3 3 2 Component of IIS longevity pathway SMK-1 WH1 PF00568.23 KSA00827.1 - 0.03 14.2 0.0 0.14 12.2 0.0 2.1 1 0 0 1 1 1 0 WH1 domain adh_short_C2 PF13561.6 KSA00828.1 - 4.6e-43 147.5 0.1 5.8e-43 147.1 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KSA00828.1 - 2e-37 128.6 0.1 2.4e-37 128.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KSA00828.1 - 2.4e-12 47.2 0.2 3.7e-12 46.5 0.2 1.2 1 0 0 1 1 1 1 KR domain ArfGap PF01412.18 KSA00829.1 - 7.2e-34 116.4 0.1 2.1e-33 114.9 0.1 1.8 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf CCDC84 PF14968.6 KSA00829.1 - 0.042 13.5 2.6 0.25 10.9 2.6 1.8 1 1 1 2 2 2 0 Coiled coil protein 84 PAP2 PF01569.21 KSA00830.1 - 7.8e-16 58.1 3.6 7.8e-16 58.1 3.6 1.4 2 0 0 2 2 2 1 PAP2 superfamily CPBP PF02517.16 KSA00830.1 - 4.9 7.6 9.7 1 9.8 6.2 1.7 2 0 0 2 2 2 0 CPBP intramembrane metalloprotease HEAT_EZ PF13513.6 KSA00831.1 - 9.3e-16 58.0 6.5 8.9e-07 29.3 0.1 8.3 7 1 2 9 9 8 2 HEAT-like repeat HEAT PF02985.22 KSA00831.1 - 2.1e-11 43.0 18.0 0.016 15.4 0.0 10.9 13 0 0 13 13 10 2 HEAT repeat HEAT_2 PF13646.6 KSA00831.1 - 3e-08 34.0 7.6 0.08 13.3 0.1 7.2 4 2 3 7 7 7 1 HEAT repeats IFRD PF05004.13 KSA00831.1 - 2.3e-07 30.3 3.7 0.00015 21.0 2.2 4.5 3 1 2 5 5 5 1 Interferon-related developmental regulator (IFRD) Cnd1 PF12717.7 KSA00831.1 - 5.4e-06 26.5 5.6 6.5e-05 23.0 0.1 3.9 2 1 2 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 KSA00831.1 - 1.2e-05 25.1 9.1 0.043 13.9 0.1 6.5 7 0 0 7 7 6 1 Armadillo/beta-catenin-like repeat IBN_N PF03810.19 KSA00831.1 - 3.3e-05 23.7 0.7 3.3e-05 23.7 0.7 2.9 3 0 0 3 3 3 1 Importin-beta N-terminal domain CLASP_N PF12348.8 KSA00831.1 - 0.0036 16.9 1.5 6.3 6.3 0.0 4.1 2 1 2 4 4 4 1 CLASP N terminal TIP120 PF08623.10 KSA00831.1 - 0.008 16.0 4.7 0.018 14.8 0.1 3.4 2 1 1 3 3 3 1 TATA-binding protein interacting (TIP20) Telomere_reg-2 PF10193.9 KSA00831.1 - 0.017 15.5 1.4 0.21 12.1 0.6 2.9 1 1 0 2 2 2 0 Telomere length regulation protein RIX1 PF08167.12 KSA00831.1 - 0.027 14.2 3.5 1.5 8.5 2.1 4.0 1 1 1 2 2 2 0 rRNA processing/ribosome biogenesis DUF1241 PF06840.11 KSA00831.1 - 0.041 13.5 0.5 0.12 12.0 0.5 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1241) DUF3385 PF11865.8 KSA00831.1 - 0.2 11.5 2.9 23 4.8 1.7 4.5 3 2 2 5 5 5 0 Domain of unknown function (DUF3385) Septin PF00735.18 KSA00832.1 - 2.6e-88 295.9 12.0 4.9e-88 295.0 5.9 2.9 2 1 0 2 2 2 1 Septin GTP_EFTU PF00009.27 KSA00832.1 - 2e-07 30.7 0.8 6e-05 22.7 0.0 2.8 3 0 0 3 3 3 2 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KSA00832.1 - 1.7e-05 24.9 0.3 8.2e-05 22.7 0.3 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KSA00832.1 - 7.5e-05 22.9 0.3 0.058 13.4 0.0 3.2 3 0 0 3 3 2 1 Dynamin family RsgA_GTPase PF03193.16 KSA00832.1 - 0.0022 17.9 2.3 0.23 11.3 0.9 3.2 2 1 0 2 2 2 1 RsgA GTPase Roc PF08477.13 KSA00832.1 - 0.0041 17.3 0.2 0.027 14.7 0.2 2.2 1 1 1 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 KSA00832.1 - 0.0065 15.8 0.4 0.32 10.3 0.1 2.6 1 1 0 2 2 2 1 AIG1 family AAA_22 PF13401.6 KSA00832.1 - 0.0082 16.4 1.0 0.035 14.4 0.1 2.5 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KSA00832.1 - 0.01 15.4 0.1 0.02 14.4 0.1 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Pox_A32 PF04665.12 KSA00832.1 - 0.011 15.3 0.2 0.022 14.2 0.2 1.5 1 0 0 1 1 1 0 Poxvirus A32 protein TsaE PF02367.17 KSA00832.1 - 0.017 15.1 0.0 0.072 13.1 0.0 2.0 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 KSA00832.1 - 0.041 14.3 0.4 0.3 11.5 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain cobW PF02492.19 KSA00832.1 - 0.082 12.5 0.0 0.3 10.6 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 KSA00832.1 - 0.14 11.9 0.1 1.8 8.3 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 KSA00832.1 - 0.22 12.0 1.3 1.7 9.1 0.0 2.5 2 0 0 2 2 2 0 ABC transporter ATP_bind_1 PF03029.17 KSA00832.1 - 0.23 11.2 1.9 1.7 8.3 0.1 2.6 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein Synaptobrevin PF00957.21 KSA00832.1 - 2.5 7.9 6.7 2.5 8.0 3.5 2.4 1 1 1 2 2 2 0 Synaptobrevin YjeF_N PF03853.15 KSA00833.1 - 1.7e-34 119.1 0.0 2.1e-34 118.9 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus DUF5470 PF17564.2 KSA00834.1 - 0.014 15.6 0.4 0.014 15.6 0.4 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5470) APG5 PF04106.12 KSA00835.1 - 2e-49 168.2 3.3 3.1e-49 167.6 3.3 1.3 1 0 0 1 1 1 1 Autophagy protein Apg5 RWD PF05773.22 KSA00835.1 - 0.035 14.4 0.4 0.073 13.4 0.4 1.6 1 0 0 1 1 1 0 RWD domain Methyltransf_23 PF13489.6 KSA00836.1 - 5.8e-16 58.8 0.0 8.7e-16 58.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KSA00836.1 - 1.2e-12 48.5 0.3 5.9e-12 46.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KSA00836.1 - 4.7e-11 43.2 0.0 1e-10 42.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KSA00836.1 - 6.3e-08 33.2 0.0 1.3e-07 32.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KSA00836.1 - 8.4e-06 25.6 0.0 5.6e-05 23.0 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 KSA00836.1 - 0.00038 19.7 0.0 0.51 9.5 0.0 2.1 2 0 0 2 2 2 2 NNMT/PNMT/TEMT family MTS PF05175.14 KSA00836.1 - 0.065 12.8 0.0 0.15 11.6 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase small domain GalP_UDP_tr_C PF02744.17 KSA00837.1 - 8.4e-68 227.3 0.6 1.9e-67 226.2 0.4 1.6 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain GalP_UDP_transf PF01087.22 KSA00837.1 - 5.6e-67 225.7 0.1 1.3e-66 224.5 0.1 1.6 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, N-terminal domain DUF4921 PF16268.5 KSA00837.1 - 0.00034 19.5 0.1 0.13 11.0 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4921) DcpS_C PF11969.8 KSA00837.1 - 0.001 19.5 0.1 0.0027 18.2 0.0 1.8 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DUF2935 PF11155.8 KSA00837.1 - 0.0027 18.0 0.1 0.006 16.9 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF2935) HIT PF01230.23 KSA00837.1 - 0.012 16.3 0.0 0.049 14.4 0.0 2.1 2 0 0 2 2 2 0 HIT domain GDP_Man_Dehyd PF16363.5 KSA00838.1 - 7.5e-62 209.6 0.0 1e-61 209.2 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KSA00838.1 - 2e-44 151.9 0.0 2.4e-44 151.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KSA00838.1 - 5.2e-10 38.9 0.0 2.3e-09 36.8 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 KSA00838.1 - 4e-08 32.6 0.0 6.4e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KSA00838.1 - 3.9e-07 29.5 0.0 3.3e-06 26.5 0.0 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KSA00838.1 - 1.8e-05 24.0 0.0 3.7e-05 23.0 0.0 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain DUF2834 PF11196.8 KSA00838.1 - 0.12 12.8 0.0 0.66 10.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2834) Sybindin PF04099.12 KSA00839.1 - 1.6e-35 122.2 6.6 1.3e-22 80.2 0.6 2.4 2 1 0 2 2 2 2 Sybindin-like family Sedlin_N PF04628.13 KSA00839.1 - 4.5e-08 33.3 0.5 6e-08 32.9 0.5 1.3 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region FAD-oxidase_C PF02913.19 KSA00840.1 - 2.1e-51 175.0 0.0 3.6e-51 174.2 0.0 1.4 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KSA00840.1 - 5.8e-36 123.3 0.0 9.3e-36 122.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain zf-RING_2 PF13639.6 KSA00842.1 - 3.1e-09 37.0 4.8 1.4e-07 31.7 4.8 2.2 1 1 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KSA00842.1 - 2.5e-07 30.9 4.4 1.2e-06 28.7 4.4 2.0 1 1 1 2 2 2 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KSA00842.1 - 0.00045 20.0 3.0 0.082 12.8 0.4 2.3 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KSA00842.1 - 0.0005 19.8 3.1 0.0051 16.6 0.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KSA00842.1 - 0.00072 19.5 4.7 0.21 11.6 0.0 2.3 2 0 0 2 2 2 2 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KSA00842.1 - 0.0033 17.2 0.3 0.57 10.1 0.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KSA00842.1 - 0.0038 16.9 2.5 0.034 13.9 2.5 2.2 1 1 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 KSA00842.1 - 0.011 15.5 2.6 0.19 11.6 2.6 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KSA00842.1 - 0.012 15.5 0.1 2.3 8.2 0.0 2.3 2 0 0 2 2 2 0 zinc-RING finger domain zf-ANAPC11 PF12861.7 KSA00842.1 - 0.04 14.0 1.4 0.12 12.5 1.4 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Di19 PF05605.12 KSA00842.1 - 0.084 13.2 0.1 7.9 6.9 0.0 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zinc_ribbon_9 PF14369.6 KSA00842.1 - 0.11 12.8 0.3 3.9 7.8 0.0 2.3 2 0 0 2 2 2 0 zinc-ribbon CTU2 PF10288.9 KSA00842.1 - 0.14 12.4 2.2 1.5 9.1 2.2 2.1 1 1 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 DUF1644 PF07800.12 KSA00842.1 - 0.2 11.7 2.0 1.9 8.5 2.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1644) Zn-C2H2_12 PF18112.1 KSA00842.1 - 0.92 10.0 2.6 14 6.2 0.1 2.4 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain Ribosomal_S10 PF00338.22 KSA00843.1 - 1.7e-21 76.3 0.0 4.4e-21 74.9 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein S10p/S20e FtsJ PF01728.19 KSA00844.1 - 4.3e-69 232.1 0.0 5.9e-69 231.7 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.6 KSA00844.1 - 0.16 11.8 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain tRNA-synt_2 PF00152.20 KSA00845.1 - 3.4e-76 256.3 1.1 4.3e-76 256.0 0.3 1.5 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KSA00845.1 - 1.9e-11 43.8 0.1 4.3e-11 42.6 0.1 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KSA00845.1 - 3e-07 30.2 0.1 0.0061 16.1 0.1 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) CinA_KH PF18146.1 KSA00845.1 - 0.085 13.0 0.0 9.3 6.5 0.0 2.7 1 1 1 2 2 2 0 Damage-inducible protein CinA KH domain Pdase_M17_N2 PF18295.1 KSA00846.1 - 0.061 13.6 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 M17 aminopeptidase N-terminal domain 2 DUF2951 PF11166.8 KSA00846.1 - 0.99 9.7 5.5 0.55 10.5 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2951) His_Phos_1 PF00300.22 KSA00847.1 - 2e-11 43.9 0.0 3e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF3287 PF11690.8 KSA00847.1 - 0.048 13.4 1.4 0.35 10.6 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3287) DUF4850 PF16142.5 KSA00847.1 - 0.066 12.7 0.2 0.13 11.7 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4850) TIM PF00121.18 KSA00848.1 - 2.4e-87 292.3 0.0 2.8e-87 292.1 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase TatD_DNase PF01026.21 KSA00849.1 - 4.6e-33 114.7 0.0 8.4e-33 113.8 0.0 1.3 1 1 0 1 1 1 1 TatD related DNase Glyco_transf_20 PF00982.21 KSA00850.1 - 1.5e-143 479.0 0.0 2.1e-143 478.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 KSA00850.1 - 6.5e-22 77.8 0.0 1.4e-21 76.8 0.0 1.5 1 0 0 1 1 1 1 Trehalose-phosphatase CTK3 PF12243.8 KSA00851.1 - 5.8e-37 126.4 0.8 1.3e-36 125.3 0.4 1.8 2 0 0 2 2 2 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.8 KSA00851.1 - 1.1e-21 76.8 5.9 2.3e-21 75.7 3.1 2.4 2 0 0 2 2 2 1 CTD kinase subunit gamma CTK3 C-terminus eIF-1a PF01176.19 KSA00852.1 - 6.9e-21 73.8 0.1 9.6e-21 73.4 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Mg_trans_NIPA PF05653.14 KSA00853.1 - 5.8e-108 360.5 19.6 7e-108 360.2 19.6 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KSA00853.1 - 1.3e-05 25.4 4.8 1.3e-05 25.4 4.8 3.4 3 1 0 3 3 3 1 EamA-like transporter family Saf_2TM PF18303.1 KSA00853.1 - 0.56 9.8 3.1 0.84 9.2 0.3 2.5 1 1 0 2 2 2 0 SAVED-fused 2TM effector domain TPR_8 PF13181.6 KSA00854.1 - 5.2e-07 29.4 0.4 2.3 8.6 0.0 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 KSA00854.1 - 3.2e-06 26.8 0.1 1.9 8.8 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 KSA00854.1 - 9.6e-06 26.0 0.1 0.018 15.6 0.0 4.7 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 KSA00854.1 - 0.00012 22.6 0.5 0.19 12.4 0.0 4.6 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 KSA00854.1 - 0.00038 20.1 0.4 1.7 8.6 0.0 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 KSA00854.1 - 0.0018 18.9 3.8 4.2 8.4 0.1 5.2 5 1 1 6 6 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KSA00854.1 - 0.012 15.8 2.2 0.046 14.0 1.1 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 QRPTase_C PF01729.19 KSA00854.1 - 0.012 15.4 0.0 0.028 14.2 0.0 1.5 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain TPR_12 PF13424.6 KSA00854.1 - 0.013 15.8 2.8 2 8.8 0.1 4.3 4 2 1 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 KSA00854.1 - 0.11 12.2 0.6 29 4.4 0.0 3.4 4 0 0 4 4 4 0 TPR repeat TPR_17 PF13431.6 KSA00854.1 - 0.51 10.8 5.2 1.9 9.0 0.0 3.9 4 0 0 4 4 3 0 Tetratricopeptide repeat Pkinase PF00069.25 KSA00855.1 - 9.6e-41 139.9 0.0 2.4e-40 138.6 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KSA00855.1 - 3.2e-27 95.4 0.0 5e-27 94.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KSA00855.1 - 7.1e-06 25.5 0.0 1.9e-05 24.1 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KSA00855.1 - 0.059 12.1 0.1 0.059 12.1 0.1 2.9 3 1 0 3 3 3 0 Fungal protein kinase ORC2 PF04084.14 KSA00856.1 - 5.5e-106 354.2 0.3 8e-106 353.7 0.3 1.2 1 0 0 1 1 1 1 Origin recognition complex subunit 2 RBR PF17208.3 KSA00856.1 - 3.6 8.4 10.0 0.76 10.5 0.1 3.4 3 0 0 3 3 3 0 RNA binding Region TFIIS_C PF01096.18 KSA00857.1 - 5.4e-22 77.4 2.1 5.4e-22 77.4 2.1 2.0 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 KSA00857.1 - 0.019 14.8 1.1 0.13 12.2 0.2 2.4 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.7 KSA00857.1 - 0.037 14.0 0.3 0.037 14.0 0.3 1.9 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Baculo_LEF5_C PF11792.8 KSA00857.1 - 0.061 13.0 0.2 0.098 12.3 0.2 1.4 1 0 0 1 1 1 0 Baculoviridae late expression factor 5 C-terminal domain PhnA_Zn_Ribbon PF08274.12 KSA00857.1 - 0.11 12.5 2.2 0.18 11.8 0.2 2.1 2 0 0 2 2 2 0 PhnA Zinc-Ribbon IBR PF01485.21 KSA00857.1 - 2.5 8.4 8.1 13 6.1 2.3 2.5 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain Lactamase_B_2 PF12706.7 KSA00858.1 - 2.5e-07 30.4 0.0 4.2e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DRMBL PF07522.14 KSA00858.1 - 0.0035 17.5 0.1 0.012 15.8 0.1 1.9 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B PF00753.27 KSA00858.1 - 0.22 11.5 1.4 2.5 8.1 1.4 2.1 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily Mob_Pre PF01076.19 KSA00858.1 - 7 6.4 8.4 1.7 8.4 3.7 2.3 3 0 0 3 3 3 0 Plasmid recombination enzyme Alg14 PF08660.11 KSA00859.1 - 1.8e-61 207.1 0.1 2.1e-61 206.9 0.1 1.1 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like RRM_1 PF00076.22 KSA00860.1 - 0.00036 20.3 0.1 0.00094 19.0 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KSA00860.1 - 0.27 11.3 2.3 0.42 10.7 0.0 2.3 3 0 0 3 3 3 0 RNA binding motif DUF2428 PF10350.9 KSA00861.1 - 1.6e-55 188.3 0.3 3.8e-55 187.1 0.3 1.7 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.22 KSA00861.1 - 6.3e-08 32.2 1.3 0.00066 19.7 0.0 6.4 7 0 0 7 7 7 1 HEAT repeat HEAT_2 PF13646.6 KSA00861.1 - 0.00032 21.0 0.0 0.58 10.6 0.0 4.1 5 0 0 5 5 5 2 HEAT repeats Agglutinin_C PF18021.1 KSA00861.1 - 0.0057 17.2 0.0 0.017 15.6 0.0 1.9 1 0 0 1 1 1 1 Agglutinin C-terminal SNF2_N PF00176.23 KSA00862.1 - 1.7e-05 23.7 0.5 2.8e-05 23.0 0.5 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Pox_M2 PF04887.12 KSA00862.1 - 0.042 13.4 0.0 0.07 12.6 0.0 1.4 1 1 0 1 1 1 0 Poxvirus M2 protein SNF2_N PF00176.23 KSA00863.1 - 4.2e-31 107.9 0.5 6.2e-31 107.4 0.5 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KSA00863.1 - 7.8e-16 58.4 0.2 3.2e-15 56.4 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KSA00863.1 - 0.0013 18.7 0.0 0.0035 17.4 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit bVLRF1 PF18826.1 KSA00864.1 - 1.6e-59 200.1 0.1 2.8e-59 199.3 0.1 1.4 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor Ank_5 PF13857.6 KSA00864.1 - 3.4e-05 24.0 0.0 9.2e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) FTO_NTD PF12933.7 KSA00864.1 - 0.0024 17.2 0.0 0.0059 15.9 0.0 1.6 1 0 0 1 1 1 1 FTO catalytic domain DUF1730 PF08331.10 KSA00864.1 - 0.12 12.3 2.0 2 8.4 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1730) URO-D PF01208.17 KSA00865.1 - 1.5e-127 425.5 0.0 1.7e-127 425.4 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Peptidase_M28 PF04389.17 KSA00866.1 - 4.6e-37 127.6 0.0 7.2e-37 127.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KSA00866.1 - 0.0032 17.2 0.0 0.0045 16.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 KSA00866.1 - 0.04 12.9 0.0 0.17 10.9 0.0 1.8 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase Cyclin_N PF00134.23 KSA00867.1 - 1.9e-12 47.0 1.3 3.5e-12 46.2 0.2 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain JAB PF01398.21 KSA00868.1 - 1.8e-11 44.0 0.0 6.6e-11 42.2 0.0 1.8 2 1 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 KSA00868.1 - 1.1e-05 25.8 5.7 2.6e-05 24.6 5.7 1.6 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function Polbeta PF18765.1 KSA00868.1 - 0.044 13.9 0.2 0.093 12.8 0.2 1.5 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase COMM_domain PF07258.14 KSA00868.1 - 0.1 12.7 1.0 0.2 11.8 1.0 1.5 1 0 0 1 1 1 0 COMM domain Toprim_Crpt PF13342.6 KSA00868.1 - 0.19 11.8 0.0 2 8.4 0.0 2.3 2 0 0 2 2 2 0 C-terminal repeat of topoisomerase CRF1 PF10380.9 KSA00869.1 - 3.6e-28 98.2 0.5 3.6e-28 98.2 0.5 5.1 3 1 0 3 3 3 1 Transcription factor CRF1 TFIIS_M PF07500.14 KSA00870.1 - 6.5e-16 58.8 0.4 6.9e-15 55.5 0.3 2.5 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain SPOC PF07744.13 KSA00870.1 - 6.8e-09 35.8 0.0 8.1e-07 29.1 0.0 2.4 2 0 0 2 2 2 1 SPOC domain PHD PF00628.29 KSA00870.1 - 6.9e-08 32.3 7.5 1.4e-07 31.3 7.5 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KSA00870.1 - 0.075 12.6 4.7 0.15 11.6 4.7 1.5 1 0 0 1 1 1 0 PHD-finger PHD_4 PF16866.5 KSA00870.1 - 0.22 11.6 8.5 1.7 8.8 7.7 2.6 1 1 1 2 2 2 0 PHD-finger zf-PHD-like PF15446.6 KSA00870.1 - 0.59 9.7 8.8 0.12 12.0 2.7 2.5 2 1 0 2 2 2 0 PHD/FYVE-zinc-finger like domain XPC-binding PF09280.11 KSA00870.1 - 3.4 7.5 8.3 57 3.6 8.3 2.4 1 1 0 1 1 1 0 XPC-binding domain Rad9_Rad53_bind PF08605.10 KSA00871.1 - 7.6e-38 129.6 0.4 1.7e-37 128.5 0.4 1.6 1 0 0 1 1 1 1 Fungal Rad9-like Rad53-binding BRCT_2 PF16589.5 KSA00871.1 - 4.3e-09 36.7 0.6 0.00019 21.8 0.0 3.6 3 0 0 3 3 3 2 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KSA00871.1 - 7.7e-09 35.8 7.1 1.5e-06 28.5 0.0 4.0 3 1 1 4 4 4 2 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 KSA00871.1 - 0.0026 17.6 0.4 0.016 15.0 0.0 2.6 2 0 0 2 2 2 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_3 PF18428.1 KSA00871.1 - 0.0073 16.4 0.5 0.44 10.6 0.1 3.4 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_6 PF16771.5 KSA00871.1 - 1.9 8.7 6.4 4.4 7.5 4.7 2.6 1 1 1 2 2 2 0 Regulator of Ty1 transposition protein 107 BRCT domain Pro_dh PF01619.18 KSA00872.1 - 3.3e-58 197.6 0.1 4.3e-58 197.2 0.1 1.1 1 0 0 1 1 1 1 Proline dehydrogenase IlvC PF01450.19 KSA00872.1 - 0.039 14.2 0.1 7.8 6.8 0.0 2.3 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain EAR PF07897.11 KSA00872.1 - 0.059 13.0 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Ethylene-responsive binding factor-associated repression SLS PF14611.6 KSA00873.1 - 5.1e-35 121.3 6.9 5.1e-35 121.3 6.9 2.1 2 0 0 2 2 2 1 Mitochondrial inner-membrane-bound regulator Phage_HK97_TLTM PF06120.11 KSA00874.1 - 0.0069 15.6 0.0 0.0077 15.4 0.0 1.2 1 0 0 1 1 1 1 Tail length tape measure protein TLV_coat PF00429.19 KSA00874.1 - 0.043 12.5 0.0 0.048 12.3 0.0 1.0 1 0 0 1 1 1 0 ENV polyprotein (coat polyprotein) ABC1 PF03109.16 KSA00875.1 - 3.9e-26 91.6 0.8 1.1e-25 90.2 0.2 2.1 3 0 0 3 3 3 1 ABC1 family Utp13 PF08625.11 KSA00876.1 - 1.2e-45 154.9 0.1 2e-45 154.2 0.1 1.4 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain WD40 PF00400.32 KSA00876.1 - 2.7e-44 148.2 16.8 1.4e-05 25.8 0.0 10.8 10 0 0 10 10 10 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KSA00876.1 - 1.1e-16 60.9 5.2 0.033 14.5 0.0 8.6 5 3 3 8 8 8 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KSA00876.1 - 0.00033 20.6 9.1 0.017 15.0 0.1 5.6 3 2 3 6 6 6 1 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KSA00876.1 - 0.0055 16.1 11.1 0.075 12.4 0.2 5.3 6 1 1 7 7 7 1 WD40-like domain Zn_clus PF00172.18 KSA00877.1 - 2.9e-09 36.9 10.0 4.6e-09 36.3 10.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MSC PF09402.10 KSA00878.1 - 3e-48 165.0 0.1 3e-48 165.0 0.1 2.9 4 0 0 4 4 4 1 Man1-Src1p-C-terminal domain HeH PF12949.7 KSA00878.1 - 1.3e-17 63.2 0.0 4.3e-17 61.5 0.0 2.0 1 0 0 1 1 1 1 HeH/LEM domain RWD PF05773.22 KSA00879.1 - 1.8e-20 73.4 7.1 1.8e-20 73.4 7.1 1.8 2 0 0 2 2 2 1 RWD domain GSK-3_bind PF05350.12 KSA00879.1 - 0.01 15.2 2.7 0.014 14.7 2.7 1.1 1 0 0 1 1 1 0 Glycogen synthase kinase-3 binding MADF_DNA_bdg PF10545.9 KSA00879.1 - 0.095 13.0 2.8 0.18 12.1 2.8 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like PfkB PF00294.24 KSA00879.1 - 0.65 9.2 2.3 0.75 9.0 0.5 1.8 1 1 1 2 2 2 0 pfkB family carbohydrate kinase SH3_1 PF00018.28 KSA00880.1 - 1.3e-08 34.3 1.0 2.2e-08 33.6 0.1 1.9 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KSA00880.1 - 1.9e-08 34.0 0.1 5e-08 32.7 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KSA00880.1 - 2.7e-05 23.7 0.0 4.8e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Pro_isomerase PF00160.21 KSA00882.1 - 1.9e-46 158.2 0.1 2.4e-46 157.9 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Redoxin PF08534.10 KSA00883.1 - 4.9e-29 100.9 0.0 5.4e-29 100.8 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KSA00883.1 - 0.01 15.7 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA family Avl9 PF09794.9 KSA00884.1 - 7.3e-137 456.1 7.3 1e-136 455.6 7.3 1.2 1 0 0 1 1 1 1 Transport protein Avl9 DUF2347 PF09804.9 KSA00884.1 - 2.7e-10 40.3 1.2 2.7e-10 40.3 1.2 1.9 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) SPA PF08616.10 KSA00884.1 - 1.8e-07 31.1 3.4 0.0052 16.7 0.0 3.4 3 0 0 3 3 3 2 Stabilization of polarity axis DENN PF02141.21 KSA00884.1 - 3.8e-05 23.7 4.3 3.8e-05 23.7 4.3 2.5 3 0 0 3 3 3 1 DENN (AEX-3) domain Phage_sheath_1C PF17482.2 KSA00884.1 - 0.049 13.6 2.0 0.14 12.1 2.0 1.8 1 0 0 1 1 1 0 Phage tail sheath C-terminal domain CPSF_A PF03178.15 KSA00885.1 - 3.8e-05 23.1 1.2 0.0002 20.8 0.3 2.3 2 1 0 2 2 2 1 CPSF A subunit region WD40 PF00400.32 KSA00885.1 - 3.9e-05 24.3 0.2 3.4 8.7 0.1 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat Lactonase PF10282.9 KSA00885.1 - 0.01 15.1 0.1 0.069 12.4 0.0 2.4 4 0 0 4 4 4 0 Lactonase, 7-bladed beta-propeller ABC_membrane PF00664.23 KSA00886.1 - 1.6e-87 293.6 23.6 2.5e-47 161.8 12.0 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KSA00886.1 - 8.2e-49 165.6 0.3 1.8e-28 99.7 0.2 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KSA00886.1 - 4.8e-08 32.7 6.5 0.013 14.9 2.7 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KSA00886.1 - 1.1e-05 25.4 0.3 0.1 12.7 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 KSA00886.1 - 0.00017 21.3 0.5 0.22 11.3 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KSA00886.1 - 0.00053 19.9 0.3 0.43 10.5 0.2 2.6 2 1 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 KSA00886.1 - 0.0019 18.7 9.0 0.076 13.5 0.0 3.6 4 0 0 4 4 3 2 AAA domain AAA_21 PF13304.6 KSA00886.1 - 0.0044 16.9 5.4 0.3 10.8 0.0 3.1 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KSA00886.1 - 0.008 16.6 1.4 2.3 8.6 0.1 2.8 3 0 0 3 3 2 1 AAA ATPase domain IstB_IS21 PF01695.17 KSA00886.1 - 0.019 14.7 0.0 4.3 7.0 0.0 2.7 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_7 PF12775.7 KSA00886.1 - 0.035 13.6 0.1 10 5.6 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region Roc PF08477.13 KSA00886.1 - 0.036 14.3 0.2 7.8 6.7 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 KSA00886.1 - 0.1 12.9 1.0 11 6.3 0.0 3.0 2 1 0 2 2 2 0 AAA domain AAA_15 PF13175.6 KSA00886.1 - 0.87 9.2 13.4 0.51 10.0 0.0 3.3 4 0 0 4 4 4 0 AAA ATPase domain Dynamin_N PF00350.23 KSA00886.1 - 3.6 7.6 6.6 2 8.4 0.1 2.7 3 0 0 3 3 3 0 Dynamin family Sec1 PF00995.23 KSA00887.1 - 1.9e-90 304.7 6.3 2.6e-90 304.3 6.3 1.1 1 0 0 1 1 1 1 Sec1 family TPT PF03151.16 KSA00888.1 - 1.6e-19 70.4 16.8 3.4e-19 69.3 16.8 1.5 1 1 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 KSA00888.1 - 1.9e-12 47.0 18.5 2.3e-12 46.8 18.2 1.3 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 KSA00888.1 - 2.1e-06 28.0 16.4 2.1e-06 28.0 16.4 2.7 3 0 0 3 3 3 2 EamA-like transporter family PUNUT PF16913.5 KSA00888.1 - 2.6e-05 23.6 17.4 2.7e-05 23.6 14.5 2.3 2 1 0 2 2 2 1 Purine nucleobase transmembrane transport PepSY_TM PF03929.16 KSA00888.1 - 0.25 11.0 1.4 15 5.2 0.0 2.3 2 0 0 2 2 2 0 PepSY-associated TM region PrgI PF12666.7 KSA00888.1 - 0.26 12.0 3.0 0.79 10.5 0.1 2.9 2 0 0 2 2 2 0 PrgI family protein Asp PF00026.23 KSA00889.1 - 6.1e-24 85.0 2.3 2.8e-23 82.8 2.3 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KSA00889.1 - 0.0037 17.5 0.1 0.0037 17.5 0.1 2.1 3 0 0 3 3 3 1 Xylanase inhibitor N-terminal LTV PF04180.14 KSA00890.1 - 7.5e-113 378.1 37.1 8.8e-113 377.9 37.1 1.0 1 0 0 1 1 1 1 Low temperature viability protein EF-hand_14 PF17959.1 KSA00890.1 - 0.043 14.2 1.1 3.7 8.0 0.1 2.8 2 0 0 2 2 2 0 EF-hand domain MatE PF01554.18 KSA00891.1 - 4.3e-54 182.5 28.9 2.6e-32 111.7 6.4 3.0 4 0 0 4 4 4 2 MatE SpoVAB PF13782.6 KSA00891.1 - 0.23 11.8 11.0 0.42 10.9 1.3 2.8 2 0 0 2 2 2 0 Stage V sporulation protein AB PIH1 PF08190.12 KSA00892.1 - 3e-21 75.6 0.2 5.4e-21 74.8 0.2 1.4 1 0 0 1 1 1 1 PIH1 N-terminal domain Pih1_fungal_CS PF18482.1 KSA00892.1 - 1.2e-20 73.8 2.4 2.9e-20 72.6 2.4 1.7 1 0 0 1 1 1 1 Fungal Pih1 CS domain Exo84_C PF16528.5 KSA00892.1 - 0.027 14.3 1.0 0.039 13.8 0.1 1.7 2 0 0 2 2 2 0 Exocyst component 84 C-terminal HTH_56 PF18662.1 KSA00892.1 - 0.027 14.5 0.4 0.072 13.2 0.4 1.8 1 0 0 1 1 1 0 Cch helix turn helix domain BPL_N PF09825.9 KSA00893.1 - 8.1e-138 459.6 0.0 1e-137 459.2 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.19 KSA00893.1 - 1.2e-16 60.8 0.0 2e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.17 KSA00893.1 - 1.7e-08 34.3 0.1 3.3e-08 33.3 0.1 1.5 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain ThuA PF06283.11 KSA00893.1 - 0.14 12.3 0.0 0.24 11.6 0.0 1.3 1 0 0 1 1 1 0 Trehalose utilisation zf-ANAPC11 PF12861.7 KSA00894.1 - 1e-44 150.5 5.6 1.3e-44 150.2 5.6 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KSA00894.1 - 1.4e-21 76.5 8.1 2e-21 76.0 8.1 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KSA00894.1 - 7.5e-07 29.4 14.1 1.3e-05 25.4 14.1 2.5 1 1 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KSA00894.1 - 0.00039 20.4 7.5 0.0093 16.0 5.1 2.6 2 2 0 2 2 2 1 RING-type zinc-finger zf-RING_4 PF14570.6 KSA00894.1 - 0.014 15.2 9.2 0.044 13.6 0.5 2.6 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4 PF00097.25 KSA00894.1 - 0.032 14.1 14.8 0.25 11.2 14.8 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KSA00894.1 - 0.041 14.0 2.6 0.041 14.0 2.6 2.2 2 1 0 2 2 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 KSA00894.1 - 0.095 12.6 16.2 1.5 8.8 16.2 2.5 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KSA00894.1 - 0.33 10.6 9.8 6.5 6.5 9.8 2.3 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-HC5HC2H_2 PF13832.6 KSA00894.1 - 0.46 10.7 4.9 1.2 9.3 4.9 1.8 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-RING_5 PF14634.6 KSA00894.1 - 0.51 10.3 11.6 2.1 8.4 11.6 2.1 1 1 0 1 1 1 0 zinc-RING finger domain PHD PF00628.29 KSA00894.1 - 0.63 10.0 10.0 1.8 8.5 10.0 1.8 1 1 0 1 1 1 0 PHD-finger zf-RING_11 PF17123.5 KSA00894.1 - 0.65 9.8 8.9 5.3 6.9 8.9 2.4 1 1 0 1 1 1 0 RING-like zinc finger zf-C3HC4_3 PF13920.6 KSA00894.1 - 1.3 8.9 11.5 1.3 8.9 6.3 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-HIT PF04438.16 KSA00894.1 - 1.9 8.5 6.7 0.74 9.7 2.4 2.1 2 0 0 2 2 2 0 HIT zinc finger RINGv PF12906.7 KSA00894.1 - 2 8.6 9.7 5.7 7.2 9.7 1.8 1 1 0 1 1 1 0 RING-variant domain UbiA PF01040.18 KSA00895.1 - 2.4e-48 164.7 19.5 3.1e-48 164.3 19.5 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Stork_head PF10264.9 KSA00896.1 - 0.026 14.7 0.0 1.4 9.1 0.0 2.7 2 0 0 2 2 2 0 Winged helix Storkhead-box1 domain Vps39_2 PF10367.9 KSA00896.1 - 0.027 14.9 0.1 0.49 10.9 0.0 3.0 3 0 0 3 3 3 0 Vacuolar sorting protein 39 domain 2 Cas_Csa5 PF09702.10 KSA00896.1 - 0.73 10.1 3.1 1.5 9.1 0.1 3.0 3 0 0 3 3 3 0 CRISPR-associated protein (Cas_Csa5) LEM PF03020.15 KSA00896.1 - 1.4 8.5 3.6 15 5.3 0.0 3.1 3 0 0 3 3 3 0 LEM domain AA_kinase PF00696.28 KSA00897.1 - 2.2e-36 125.7 1.3 3.3e-36 125.1 1.3 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 KSA00897.1 - 5.8e-15 55.0 0.0 1.3e-14 53.8 0.0 1.7 1 0 0 1 1 1 1 PUA domain Lipase_GDSL_2 PF13472.6 KSA00898.1 - 1.8e-19 70.8 0.0 2.5e-19 70.4 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KSA00898.1 - 5.9e-13 49.3 0.0 9.8e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Alpha-amylase PF00128.24 KSA00899.1 - 5.1e-120 401.1 3.1 5.3e-120 401.0 2.1 1.5 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 KSA00899.1 - 7.3e-06 26.0 0.0 1.5e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain hDGE_amylase PF14701.6 KSA00899.1 - 0.018 14.2 2.2 0.025 13.7 0.0 2.2 3 0 0 3 3 3 0 Glycogen debranching enzyme, glucanotransferase domain Na_Ca_ex PF01699.24 KSA00900.1 - 1.9e-21 76.6 30.8 1.6e-17 63.9 11.9 4.1 5 1 0 5 5 5 2 Sodium/calcium exchanger protein YccF PF03733.13 KSA00900.1 - 3.4e-12 46.9 7.0 3.4e-12 46.9 7.0 4.1 4 0 0 4 4 4 1 Inner membrane component domain NFACT-R_2 PF18297.1 KSA00900.1 - 0.11 12.7 0.0 0.26 11.5 0.0 1.6 1 0 0 1 1 1 0 NFACT protein RNA binding domain DER1 PF04511.15 KSA00901.1 - 4.8e-24 85.4 16.6 2.7e-19 69.9 8.6 2.1 1 1 1 2 2 2 2 Der1-like family LSM PF01423.22 KSA00902.1 - 2.3e-13 49.6 0.1 3.3e-13 49.1 0.1 1.3 1 0 0 1 1 1 1 LSM domain DUF5030 PF16433.5 KSA00902.1 - 0.04 13.3 0.0 0.051 12.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5030) Mitoc_mL59 PF18126.1 KSA00903.1 - 1e-28 100.2 2.0 1.5e-28 99.6 2.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein mL59 ADH_N PF08240.12 KSA00904.1 - 2.3e-26 91.8 0.4 4.6e-26 90.8 0.1 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KSA00904.1 - 5.8e-25 87.8 0.0 9.2e-25 87.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KSA00904.1 - 3.7e-09 36.4 0.2 8.7e-09 35.2 0.0 1.7 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 KSA00904.1 - 0.00022 20.6 0.3 0.00035 19.9 0.3 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 KSA00904.1 - 0.0036 16.6 0.0 0.013 14.8 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 KSA00904.1 - 0.0089 15.6 0.3 0.015 14.8 0.3 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_3 PF13738.6 KSA00904.1 - 0.035 13.4 0.6 0.061 12.6 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ADH_zinc_N_2 PF13602.6 KSA00904.1 - 0.035 15.2 0.0 0.11 13.5 0.0 1.9 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Pyr_redox PF00070.27 KSA00904.1 - 0.047 14.3 0.8 0.25 11.9 0.7 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KSA00904.1 - 0.053 12.2 1.2 0.076 11.7 1.2 1.2 1 0 0 1 1 1 0 HI0933-like protein Cas_csx3 PF09620.10 KSA00904.1 - 0.077 12.9 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_csx3) FAD_binding_3 PF01494.19 KSA00904.1 - 0.09 12.0 0.1 0.14 11.4 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain 2-Hacid_dh_C PF02826.19 KSA00904.1 - 0.095 12.1 0.1 0.17 11.3 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ATP-synt_DE_N PF02823.16 KSA00905.1 - 1.4e-20 73.0 0.0 2.4e-20 72.2 0.0 1.4 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain HisKA_2 PF07568.12 KSA00905.1 - 0.074 13.1 0.2 2.6 8.2 0.0 2.2 2 0 0 2 2 2 0 Histidine kinase Med2 PF11214.8 KSA00906.1 - 4.2e-34 116.7 7.8 4.2e-34 116.7 7.8 3.9 1 1 1 2 2 1 1 Mediator complex subunit 2 CDC45 PF02724.14 KSA00906.1 - 0.027 12.8 25.2 0.034 12.4 25.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Dapper PF15268.6 KSA00906.1 - 0.076 11.9 15.5 0.087 11.7 15.5 1.0 1 0 0 1 1 1 0 Dapper Asp-B-Hydro_N PF05279.11 KSA00906.1 - 0.094 12.8 28.2 0.13 12.3 28.2 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF2052 PF09747.9 KSA00906.1 - 0.1 12.7 28.5 0.17 12.0 28.5 1.4 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Borrelia_P83 PF05262.11 KSA00906.1 - 0.15 10.5 25.1 0.18 10.2 25.1 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein GAGA_bind PF06217.12 KSA00906.1 - 0.18 12.1 14.4 0.26 11.5 14.4 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family Velvet PF11754.8 KSA00906.1 - 0.61 10.0 6.3 0.74 9.7 6.3 1.2 1 0 0 1 1 1 0 Velvet factor Presenilin PF01080.17 KSA00906.1 - 0.73 8.5 19.3 0.86 8.3 19.3 1.1 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 KSA00906.1 - 0.78 9.5 25.7 1.4 8.6 25.7 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 AAA_11 PF13086.6 KSA00906.1 - 1 9.1 18.0 1.7 8.4 18.0 1.4 1 0 0 1 1 1 0 AAA domain DUF2201_N PF13203.6 KSA00906.1 - 1 8.9 9.8 1.4 8.5 9.8 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Hid1 PF12722.7 KSA00906.1 - 1.3 7.1 16.5 1.6 6.7 16.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SOBP PF15279.6 KSA00906.1 - 2 9.0 12.6 3 8.4 12.6 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein ALMT PF11744.8 KSA00906.1 - 2.6 6.8 14.2 3.2 6.5 14.2 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter SLC12 PF03522.15 KSA00906.1 - 3 6.8 20.0 4.4 6.2 20.0 1.2 1 0 0 1 1 1 0 Solute carrier family 12 CobT PF06213.12 KSA00906.1 - 3.3 7.0 23.6 6.6 6.0 23.6 1.5 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CDC27 PF09507.10 KSA00906.1 - 3.5 6.9 32.9 5.3 6.3 32.9 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Zip PF02535.22 KSA00906.1 - 5 6.2 9.0 5.8 6.0 9.0 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Membralin PF09746.9 KSA00906.1 - 6.2 5.7 12.4 8.5 5.3 12.4 1.3 1 0 0 1 1 1 0 Tumour-associated protein PA26 PF04636.13 KSA00906.1 - 8.9 5.1 15.0 14 4.5 15.0 1.4 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Rad21_Rec8_N PF04825.13 KSA00907.1 - 6.7e-28 97.0 0.2 1.7e-27 95.8 0.2 1.7 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 KSA00907.1 - 1.8e-09 36.7 0.0 5.8e-09 35.1 0.0 1.8 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein WD40 PF00400.32 KSA00908.1 - 1.1e-07 32.4 5.1 1.6 9.7 0.1 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat SLD5_C PF16922.5 KSA00909.1 - 8.2e-12 45.1 1.4 1.5e-11 44.3 1.4 1.4 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 KSA00909.1 - 1.7e-07 31.7 1.0 5e-07 30.2 1.0 1.8 1 1 0 1 1 1 1 GINS complex protein WD40 PF00400.32 KSA00910.1 - 1.3e-10 41.7 2.5 0.00018 22.2 0.1 4.5 3 0 0 3 3 3 2 WD domain, G-beta repeat Zn_ribbon_17 PF17120.5 KSA00910.1 - 6.9e-07 28.8 6.6 1.6e-06 27.6 6.6 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-rbx1 PF12678.7 KSA00910.1 - 0.2 12.0 7.3 0.65 10.3 7.3 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KSA00910.1 - 0.38 11.1 12.3 0.019 15.3 6.0 2.2 1 1 1 2 2 2 0 Ring finger domain zf-C3HC4 PF00097.25 KSA00910.1 - 2.4 8.1 11.5 0.039 13.8 3.2 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Hydrolase_4 PF12146.8 KSA00911.1 - 5.6e-15 55.3 0.0 7.5e-10 38.5 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KSA00911.1 - 5.9e-10 39.2 0.1 3.2e-07 30.3 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold DUF818 PF05677.12 KSA00911.1 - 5.6e-05 22.3 0.6 8.7e-05 21.6 0.6 1.2 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Abhydrolase_2 PF02230.16 KSA00911.1 - 0.00041 20.2 0.3 0.0017 18.2 0.2 1.9 1 1 1 2 2 2 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 KSA00911.1 - 0.0091 15.5 0.2 0.046 13.2 0.2 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family BAAT_C PF08840.11 KSA00911.1 - 0.012 15.6 0.2 0.14 12.0 0.1 2.4 1 1 2 3 3 3 0 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.18 KSA00911.1 - 0.04 13.5 0.0 0.066 12.8 0.0 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Lipase_3 PF01764.25 KSA00911.1 - 0.044 13.7 0.0 0.068 13.0 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) AXE1 PF05448.12 KSA00911.1 - 0.045 12.4 0.1 0.24 10.0 0.0 2.2 1 1 2 3 3 3 0 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.7 KSA00911.1 - 0.049 14.2 0.0 0.063 13.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family IF4E PF01652.18 KSA00912.1 - 2.6e-55 186.6 2.6 3.1e-55 186.3 2.6 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E KRE1 PF17056.5 KSA00913.1 - 1.5e-27 95.1 11.5 2e-27 94.7 11.5 1.2 1 0 0 1 1 1 1 Killer toxin-resistance protein 1 BMC PF00936.19 KSA00913.1 - 0.1 12.6 1.8 1.5 8.9 1.8 2.4 1 1 0 1 1 1 0 BMC domain TRAUB PF08164.12 KSA00914.1 - 8.9e-26 90.2 0.1 8.9e-26 90.2 0.1 3.3 3 0 0 3 3 3 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.6 KSA00914.1 - 2.2e-23 83.5 2.9 2.2e-23 83.5 2.9 4.0 3 2 0 3 3 3 1 Apoptosis antagonizing transcription factor GPR_Gpa2_C PF11970.8 KSA00915.1 - 1.3e-34 118.1 2.3 2e-34 117.5 2.3 1.3 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term Fungal_trans PF04082.18 KSA00916.1 - 2.5e-16 59.5 1.5 4.9e-16 58.5 0.1 2.2 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KSA00917.1 - 3.5e-10 39.8 12.4 5.2e-10 39.3 12.4 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PSI_integrin PF17205.3 KSA00917.1 - 0.0045 16.7 1.4 0.01 15.6 1.4 1.6 1 0 0 1 1 1 1 Integrin plexin domain Sugar_tr PF00083.24 KSA00918.1 - 3.8e-110 368.8 27.9 5.1e-110 368.4 27.9 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KSA00918.1 - 1.6e-25 89.8 22.7 1.6e-25 89.8 22.7 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily adh_short_C2 PF13561.6 KSA00919.1 - 2.1e-33 115.9 0.0 2.3e-33 115.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KSA00919.1 - 2.3e-14 53.3 0.1 2.9e-14 53.0 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short PF00106.25 KSA00920.1 - 2.8e-06 26.9 0.1 3.1e-06 26.8 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KSA00920.1 - 9.9e-05 22.0 0.2 0.00013 21.6 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.8 KSA00920.1 - 0.1 12.4 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase adh_short_C2 PF13561.6 KSA00921.1 - 1.1e-57 195.3 0.0 1.3e-57 195.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KSA00921.1 - 2.6e-33 115.1 0.1 3.1e-33 114.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KSA00921.1 - 7.5e-09 35.8 0.1 1.4e-08 34.9 0.1 1.3 1 1 0 1 1 1 1 KR domain F420_oxidored PF03807.17 KSA00921.1 - 0.04 14.5 0.1 0.09 13.4 0.1 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.21 KSA00921.1 - 0.049 13.1 0.2 0.2 11.1 0.0 1.9 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family Aminotran_3 PF00202.21 KSA00922.1 - 8.8e-89 298.0 0.1 1.1e-88 297.7 0.1 1.0 1 0 0 1 1 1 1 Aminotransferase class-III DUF1746 PF08508.10 KSA00923.1 - 8.4e-36 122.8 2.7 1.5e-35 122.0 2.7 1.4 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) RNA_pol_A_bac PF01000.26 KSA00924.1 - 3.7e-29 101.4 0.0 7.1e-29 100.4 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 KSA00924.1 - 1.3e-21 75.8 0.0 2e-21 75.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain EMP24_GP25L PF01105.24 KSA00925.1 - 7.6e-47 159.6 0.3 8.9e-47 159.4 0.3 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF2569 PF10754.9 KSA00925.1 - 0.018 15.5 1.4 0.019 15.4 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2569) TbpB_B_D PF01298.18 KSA00925.1 - 0.17 12.3 0.6 0.79 10.1 0.0 1.9 1 1 1 2 2 2 0 C-lobe and N-lobe beta barrels of Tf-binding protein B Bot1p PF12298.8 KSA00926.1 - 1.2e-54 185.1 1.0 1.8e-54 184.5 1.0 1.3 1 0 0 1 1 1 1 Eukaryotic mitochondrial regulator protein ArsR PF09824.9 KSA00926.1 - 0.0052 16.4 0.2 0.0085 15.7 0.2 1.3 1 0 0 1 1 1 1 ArsR transcriptional regulator Pkinase PF00069.25 KSA00927.1 - 3.4e-38 131.5 0.1 1.9e-34 119.2 0.0 3.8 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 KSA00927.1 - 6.4e-15 55.1 0.0 7.5e-11 41.8 0.0 3.9 4 1 0 4 4 4 2 Protein tyrosine kinase APH PF01636.23 KSA00927.1 - 0.01 15.8 0.1 0.02 14.8 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KSA00927.1 - 0.062 12.6 0.0 1.3 8.2 0.0 2.3 1 1 0 1 1 1 0 Kinase-like Kinesin_assoc PF16183.5 KSA00928.1 - 6.7 6.8 8.5 0.43 10.7 2.7 2.0 2 2 0 2 2 2 0 Kinesin-associated Sulfate_transp PF00916.20 KSA00929.1 - 2.2e-74 250.5 21.9 3.5e-74 249.9 21.9 1.3 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KSA00929.1 - 1.2e-11 44.3 0.1 3.8e-11 42.6 0.1 1.8 2 0 0 2 2 2 1 STAS domain PCDO_beta_N PF12391.8 KSA00929.1 - 0.56 9.9 3.6 0.18 11.5 0.5 1.8 2 0 0 2 2 2 0 Protocatechuate 3,4-dioxygenase beta subunit N terminal E1_DerP2_DerF2 PF02221.15 KSA00930.1 - 1e-28 100.4 0.1 1.3e-28 100.1 0.1 1.1 1 0 0 1 1 1 1 ML domain Alph_Pro_TM PF09608.10 KSA00930.1 - 0.18 11.6 0.0 0.22 11.3 0.0 1.2 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) FTR1 PF03239.14 KSA00931.1 - 3.7e-76 256.2 7.1 2e-50 171.7 4.4 2.0 2 0 0 2 2 2 2 Iron permease FTR1 family Pex2_Pex12 PF04757.14 KSA00931.1 - 0.0074 15.9 0.0 1 8.9 0.0 2.6 2 1 1 3 3 3 2 Pex2 / Pex12 amino terminal region Orf78 PF06024.12 KSA00931.1 - 0.027 14.8 0.2 0.46 10.8 0.0 2.9 3 1 1 4 4 4 0 Orf78 (ac78) DUF2062 PF09835.9 KSA00931.1 - 3.6 7.4 8.8 2.3 8.1 0.0 2.8 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2062) Cu-binding_MopE PF11617.8 KSA00931.1 - 6.1 7.1 6.8 0.81 9.9 2.6 1.7 2 0 0 2 2 2 0 Putative metal-binding motif SH3_1 PF00018.28 KSA00932.1 - 0.0038 16.8 0.0 0.025 14.2 0.0 2.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KSA00932.1 - 0.018 14.9 0.1 0.12 12.3 0.0 2.4 2 0 0 2 2 2 0 Variant SH3 domain HEAT_EZ PF13513.6 KSA00933.1 - 5e-27 94.0 0.1 2.3e-10 40.8 0.0 7.9 8 1 1 9 9 9 3 HEAT-like repeat HEAT PF02985.22 KSA00933.1 - 3.1e-22 76.7 14.0 0.00012 22.1 0.0 11.1 12 0 0 12 12 12 4 HEAT repeat HEAT_2 PF13646.6 KSA00933.1 - 1.1e-19 70.5 0.0 0.00063 20.1 0.0 8.7 5 3 3 9 9 9 5 HEAT repeats Vac14_Fab1_bd PF12755.7 KSA00933.1 - 6e-14 52.4 0.1 0.00092 19.8 0.1 6.2 6 2 1 7 7 7 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KSA00933.1 - 1.5e-09 38.1 2.0 0.0014 18.7 0.1 4.9 4 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 IBN_N PF03810.19 KSA00933.1 - 1.6e-06 27.9 1.1 4.8e-05 23.2 0.2 3.5 3 0 0 3 3 3 1 Importin-beta N-terminal domain Arm PF00514.23 KSA00933.1 - 0.00018 21.4 11.7 0.63 10.2 0.0 6.7 7 0 0 7 7 7 1 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.20 KSA00933.1 - 0.00049 18.8 1.6 0.17 10.4 0.1 3.4 3 2 0 3 3 3 1 Adaptin N terminal region HEAT_PBS PF03130.16 KSA00933.1 - 0.013 16.1 3.4 1.3e+02 3.7 0.1 6.0 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat RTP1_C1 PF10363.9 KSA00933.1 - 0.024 14.8 0.8 4.9 7.4 0.0 4.2 5 0 0 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 BP28CT PF08146.12 KSA00933.1 - 0.063 13.1 0.0 1.1 9.1 0.0 2.9 3 0 0 3 3 3 0 BP28CT (NUC211) domain DUF1981 PF09324.10 KSA00933.1 - 0.087 12.7 3.0 6.8 6.6 0.1 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF1981) DUF4366 PF14283.6 KSA00933.1 - 0.23 11.5 6.3 0.44 10.6 6.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) PBP1_TM PF14812.6 KSA00933.1 - 9.5 6.7 9.8 20 5.6 9.8 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PIG-P PF08510.12 KSA00934.1 - 3.3e-28 98.0 3.1 3.7e-28 97.9 3.1 1.0 1 0 0 1 1 1 1 PIG-P CPSase_L_D2 PF02786.17 KSA00935.1 - 5.3e-110 365.9 0.1 2.5e-84 282.0 0.0 2.4 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 KSA00935.1 - 3.1e-39 134.1 0.1 8.1e-39 132.7 0.0 1.8 2 0 0 2 2 2 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 KSA00935.1 - 2.4e-20 72.8 0.1 9.2e-09 35.1 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KSA00935.1 - 6.3e-17 61.8 0.6 3.3e-07 30.1 0.0 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 KSA00935.1 - 5.8e-11 42.2 0.0 0.00013 21.7 0.0 3.0 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon RimK PF08443.11 KSA00935.1 - 6e-07 29.2 0.1 0.043 13.4 0.0 2.6 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_5 PF13549.6 KSA00935.1 - 0.00013 21.5 0.1 0.051 13.0 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.19 KSA00935.1 - 0.00028 20.7 0.3 0.15 11.8 0.1 2.8 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain TrkA_N PF02254.18 KSA00935.1 - 0.076 13.3 3.0 0.094 13.0 0.0 2.7 4 0 0 4 4 4 0 TrkA-N domain Epimerase PF01370.21 KSA00935.1 - 0.096 12.1 0.1 0.28 10.6 0.1 1.8 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family MFS_1 PF07690.16 KSA00936.1 - 2.6e-10 39.7 46.2 3.8e-06 26.1 17.5 2.9 2 1 1 3 3 3 2 Major Facilitator Superfamily SNAP PF14938.6 KSA00937.1 - 1.5e-105 352.7 10.8 1.7e-105 352.5 10.8 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_7 PF13176.6 KSA00937.1 - 0.00056 19.8 3.1 0.019 15.0 0.1 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 KSA00937.1 - 0.0017 18.6 7.7 0.26 11.6 0.4 3.4 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KSA00937.1 - 0.002 18.1 8.5 4.7 7.6 0.0 4.9 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 KSA00937.1 - 0.0041 17.8 1.2 0.64 11.0 0.0 4.1 2 1 2 4 4 4 1 Tetratricopeptide repeat RPN7 PF10602.9 KSA00937.1 - 0.0097 15.6 1.1 0.11 12.3 0.1 2.7 1 1 2 3 3 3 1 26S proteasome subunit RPN7 MIT PF04212.18 KSA00937.1 - 0.016 15.3 10.4 0.41 10.7 0.5 4.5 2 1 2 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_15 PF13429.6 KSA00937.1 - 0.018 14.3 0.6 0.085 12.1 0.1 2.1 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 KSA00937.1 - 0.027 14.7 7.0 0.11 12.8 0.1 3.9 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 KSA00937.1 - 0.039 14.6 1.7 3.2 8.6 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 KSA00937.1 - 0.095 12.6 14.3 0.31 10.9 0.0 5.2 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 KSA00937.1 - 0.1 13.3 0.6 1.8 9.3 0.0 2.9 2 1 0 3 3 3 0 Tetratricopeptide repeat TPR_MalT PF17874.1 KSA00937.1 - 0.11 11.9 0.3 0.39 10.1 0.0 1.7 1 1 1 2 2 2 0 MalT-like TPR region Mad3_BUB1_I PF08311.12 KSA00937.1 - 0.16 11.9 2.5 3.4 7.7 0.1 3.1 3 0 0 3 3 3 0 Mad3/BUB1 homology region 1 TOM20_plant PF06552.12 KSA00937.1 - 0.23 11.2 3.5 1.2 8.8 3.2 2.1 1 1 1 2 2 2 0 Plant specific mitochondrial import receptor subunit TOM20 NSF PF02071.20 KSA00937.1 - 0.24 12.3 18.2 0.4 11.6 0.1 6.5 7 1 1 8 8 6 0 Aromatic-di-Alanine (AdAR) repeat Nnf1 PF03980.14 KSA00938.1 - 2e-26 92.5 1.2 2e-26 92.5 1.2 1.8 2 0 0 2 2 2 1 Nnf1 Syntaxin-6_N PF09177.11 KSA00938.1 - 0.43 11.2 7.1 2 9.0 0.5 2.5 2 1 0 2 2 2 0 Syntaxin 6, N-terminal T6PP_N PF18572.1 KSA00938.1 - 1.1 9.1 5.7 0.23 11.3 0.6 2.1 2 1 0 2 2 2 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain HALZ PF02183.18 KSA00938.1 - 3 8.2 6.7 17 5.7 0.7 3.0 3 0 0 3 3 3 0 Homeobox associated leucine zipper Ribosomal_S15 PF00312.22 KSA00939.1 - 1.4e-25 89.3 1.1 1.4e-25 89.3 1.1 2.2 2 0 0 2 2 2 1 Ribosomal protein S15 Aquarius_N PF16399.5 KSA00940.1 - 6.4e-41 140.3 22.2 1.3e-35 122.7 18.9 2.7 1 1 0 2 2 2 2 Intron-binding protein aquarius N-terminus DUF5390 PF17365.2 KSA00940.1 - 0.044 14.1 0.7 0.5 10.6 0.3 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5390) GATA PF00320.27 KSA00941.1 - 9.4e-15 53.9 4.5 2.2e-14 52.8 4.5 1.7 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.12 KSA00941.1 - 0.0026 17.2 0.5 0.0056 16.2 0.5 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding Pox_A_type_inc PF04508.12 KSA00941.1 - 0.0091 15.8 1.9 1.9 8.5 0.4 2.7 2 0 0 2 2 2 2 Viral A-type inclusion protein repeat Elf1 PF05129.13 KSA00941.1 - 0.12 12.4 0.3 0.31 11.1 0.3 1.6 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like Auto_anti-p27 PF06677.12 KSA00941.1 - 0.21 11.8 1.0 0.36 11.0 1.0 1.4 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) PGM_PMM_I PF02878.16 KSA00942.1 - 2.5e-39 134.1 0.1 3.8e-39 133.6 0.1 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 KSA00942.1 - 4e-25 88.2 0.0 9.2e-25 87.1 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 KSA00942.1 - 2.6e-14 53.7 0.1 7e-14 52.3 0.1 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 KSA00942.1 - 1.7e-09 37.7 0.0 4e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Aminotran_1_2 PF00155.21 KSA00943.1 - 3e-79 266.8 0.1 3.5e-79 266.6 0.1 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II CHDNT PF08073.12 KSA00943.1 - 0.026 14.5 0.0 0.74 9.8 0.0 2.6 2 0 0 2 2 2 0 CHDNT (NUC034) domain DUF4250 PF14056.6 KSA00943.1 - 0.041 13.8 0.6 0.13 12.3 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4250) Sugar_tr PF00083.24 KSA00944.1 - 4e-154 513.8 33.8 4.6e-154 513.6 33.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KSA00944.1 - 3e-31 108.6 29.0 1.6e-26 93.0 18.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KSA00944.1 - 4.1e-06 25.5 2.1 4.1e-06 25.5 2.1 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Ni_hydr_CYTB PF01292.20 KSA00944.1 - 0.0014 18.2 0.2 0.058 13.0 0.4 2.8 2 0 0 2 2 2 1 Prokaryotic cytochrome b561 Bmt2 PF11968.8 KSA00945.1 - 1.1e-87 293.5 0.1 1.5e-87 293.0 0.1 1.2 1 0 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Methyltransf_23 PF13489.6 KSA00945.1 - 3.3e-05 23.8 0.0 6.7e-05 22.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain DUF4635 PF15466.6 KSA00945.1 - 0.055 13.0 0.0 0.16 11.5 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4635) DEAD PF00270.29 KSA00946.1 - 9.6e-37 126.4 0.0 2.4e-36 125.1 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KSA00946.1 - 1.6e-28 99.3 0.0 2.2e-27 95.6 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KSA00946.1 - 0.8 10.0 3.0 0.98 9.7 0.2 2.7 3 1 0 3 3 3 0 AAA domain eRF1_2 PF03464.15 KSA00947.1 - 3.2e-47 160.2 0.1 5.7e-47 159.4 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 KSA00947.1 - 8.6e-37 126.1 0.1 2e-36 124.9 0.1 1.7 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 KSA00947.1 - 1.6e-19 70.2 0.0 2.7e-19 69.4 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 baeRF_family10 PF18854.1 KSA00947.1 - 2e-10 41.0 0.0 3.1e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 acVLRF1 PF18859.1 KSA00947.1 - 8.3e-09 35.8 0.0 1.3e-08 35.3 0.0 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor DUF3440 PF11922.8 KSA00947.1 - 0.037 13.7 0.0 0.068 12.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3440) PTSIIB_sorb PF03830.15 KSA00947.1 - 0.069 13.4 0.3 0.23 11.7 0.1 2.0 2 0 0 2 2 2 0 PTS system sorbose subfamily IIB component Tnp_DNA_bind PF14706.6 KSA00947.1 - 0.079 12.8 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Transposase DNA-binding CDC50 PF03381.15 KSA00948.1 - 1.2e-90 303.8 1.5 1.6e-90 303.4 1.5 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family ADH_N_2 PF16884.5 KSA00949.1 - 6.1e-21 74.3 0.0 7.2e-21 74.1 0.0 1.1 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase Ribosomal_L50 PF10501.9 KSA00950.1 - 1.2e-34 118.8 0.3 2.5e-34 117.7 0.3 1.6 1 0 0 1 1 1 1 Ribosomal subunit 39S CBS PF00571.28 KSA00951.1 - 1.3e-30 105.6 9.6 1.2e-10 41.6 0.0 5.7 5 1 0 5 5 5 4 CBS domain PB1 PF00564.24 KSA00951.1 - 9.2e-09 35.1 0.8 2.6e-08 33.7 0.8 1.8 1 1 0 1 1 1 1 PB1 domain Sec34 PF04136.15 KSA00951.1 - 0.006 16.5 0.0 0.024 14.5 0.1 1.9 2 0 0 2 2 2 1 Sec34-like family ASCH PF04266.14 KSA00951.1 - 0.0075 16.8 0.0 0.18 12.4 0.0 2.4 2 0 0 2 2 2 1 ASCH domain Neprosin_AP PF14365.6 KSA00951.1 - 0.01 16.3 0.4 0.01 16.3 0.4 2.2 2 0 0 2 2 2 0 Neprosin activation peptide Prenyltransf PF01255.19 KSA00952.1 - 4.2e-61 206.3 0.9 5.1e-61 206.1 0.9 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Vma12 PF11712.8 KSA00953.1 - 1.1e-41 142.2 1.9 1.4e-41 141.8 1.9 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF2207 PF09972.9 KSA00953.1 - 0.023 13.5 0.2 0.024 13.4 0.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) tRNA_SAD PF07973.14 KSA00954.1 - 4.3e-10 39.5 1.2 1e-09 38.3 0.2 2.1 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain tRNA-synt_2c PF01411.19 KSA00954.1 - 1.3e-06 27.2 0.0 2.9e-06 26.1 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class II (A) Ribosomal_S9 PF00380.19 KSA00955.1 - 7.7e-42 142.6 0.4 1.6e-41 141.6 0.4 1.5 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Myb_DNA-binding PF00249.31 KSA00956.1 - 1.3e-13 50.9 0.0 6.6e-06 26.2 0.0 3.0 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KSA00956.1 - 0.0055 16.6 0.5 0.029 14.2 0.5 2.3 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-bind_6 PF13921.6 KSA00956.1 - 0.024 14.9 0.1 0.57 10.5 0.1 3.0 2 0 0 2 2 2 0 Myb-like DNA-binding domain Tox-ODYAM1 PF15642.6 KSA00956.1 - 1 8.2 5.2 3.2 6.6 0.3 2.2 2 0 0 2 2 2 0 Toxin in Odyssella and Amoebophilus DUF1840 PF08895.11 KSA00956.1 - 2.6 8.4 0.0 2.6 8.4 0.0 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1840) AAA PF00004.29 KSA00957.1 - 1.4e-11 44.9 0.1 1.3e-10 41.8 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KSA00957.1 - 5.1e-09 36.5 0.0 1.2e-08 35.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KSA00957.1 - 1.6e-05 25.4 0.0 5.3e-05 23.7 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_lid_10 PF17872.1 KSA00957.1 - 8.6e-05 22.6 0.2 0.00027 21.0 0.1 1.9 2 0 0 2 2 2 1 AAA lid domain AAA_19 PF13245.6 KSA00957.1 - 0.0015 18.8 0.0 0.0043 17.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KSA00957.1 - 0.0036 17.3 0.4 0.0085 16.0 0.4 1.6 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea T2SSE PF00437.20 KSA00957.1 - 0.022 13.8 0.1 0.044 12.8 0.1 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_11 PF13086.6 KSA00957.1 - 0.04 13.7 0.1 0.11 12.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KSA00957.1 - 0.064 12.8 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 KSA00957.1 - 0.12 12.1 0.2 9.7 5.9 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein CENP-S PF15630.6 KSA00958.1 - 2.6e-29 101.4 0.0 3.1e-29 101.2 0.0 1.1 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KSA00958.1 - 1.6e-06 28.1 0.0 2.1e-06 27.8 0.0 1.3 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Bromo_TP PF07524.13 KSA00958.1 - 0.0021 18.1 0.0 0.0027 17.7 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated Histone PF00125.24 KSA00958.1 - 0.0072 16.7 0.0 0.0086 16.4 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Amelotin PF15757.5 KSA00958.1 - 0.035 13.7 0.0 0.041 13.5 0.0 1.1 1 0 0 1 1 1 0 Amelotin partial_CstF PF15861.5 KSA00958.1 - 0.058 13.2 0.3 5.8 6.8 0.0 2.5 3 0 0 3 3 3 0 Partial cleavage stimulation factor domain TFIID-18kDa PF02269.16 KSA00958.1 - 0.071 13.2 0.0 0.13 12.3 0.0 1.4 1 1 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit DUF3337 PF11816.8 KSA00959.1 - 1.9e-41 141.8 0.3 4.1e-41 140.7 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) WD40 PF00400.32 KSA00959.1 - 4.2e-11 43.2 14.4 5.5e-05 23.9 0.1 6.7 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KSA00959.1 - 0.016 15.5 0.1 4.7 7.6 0.0 3.6 2 1 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain RNA_pol_Rpb5_C PF01191.19 KSA00960.1 - 1.9e-32 110.9 0.4 2.9e-32 110.3 0.4 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 KSA00960.1 - 2.3e-11 44.1 0.0 4.2e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Sof1 PF04158.14 KSA00960.1 - 0.0024 18.1 0.1 0.0043 17.3 0.1 1.3 1 0 0 1 1 1 1 Sof1-like domain SH3_2 PF07653.17 KSA00960.1 - 0.043 13.5 0.1 0.18 11.5 0.1 2.0 1 1 0 1 1 1 0 Variant SH3 domain AAA_3 PF07726.11 KSA00960.1 - 0.098 12.5 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RibD_C PF01872.17 KSA00961.1 - 2.7e-34 118.8 0.0 3.1e-34 118.6 0.0 1.1 1 0 0 1 1 1 1 RibD C-terminal domain Head_binding PF09008.10 KSA00961.1 - 0.16 12.2 0.0 0.48 10.7 0.0 1.8 1 1 0 1 1 1 0 Head binding MFAP1 PF06991.11 KSA00962.1 - 6.7e-22 78.4 20.5 8.7e-22 78.0 20.5 1.1 1 0 0 1 1 1 1 Microfibril-associated/Pre-mRNA processing SURF2 PF05477.11 KSA00962.1 - 6.6 6.4 15.0 9.8 5.8 14.3 1.6 1 1 0 1 1 1 0 Surfeit locus protein 2 (SURF2) ELO PF01151.18 KSA00963.1 - 2.1e-59 201.1 29.3 2.9e-59 200.6 29.3 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family PfkB PF00294.24 KSA00964.1 - 1.9e-55 188.3 0.9 2.5e-55 187.9 0.9 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 KSA00964.1 - 0.0046 16.4 0.3 0.0078 15.6 0.3 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase MMTV_SAg PF01054.17 KSA00964.1 - 0.048 13.2 0.0 0.089 12.3 0.0 1.4 1 0 0 1 1 1 0 Mouse mammary tumour virus superantigen PCI PF01399.27 KSA00965.1 - 7.3e-10 39.3 3.0 2e-09 37.9 0.6 3.1 2 0 0 2 2 2 1 PCI domain BCIP PF13862.6 KSA00966.1 - 1.8e-66 223.9 4.1 2.3e-66 223.5 4.1 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein WD40 PF00400.32 KSA00967.1 - 5.2e-23 80.9 6.3 1.8e-06 28.6 0.1 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KSA00967.1 - 1.8e-05 25.0 0.0 1.6 9.1 0.0 3.7 2 2 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain BAR PF03114.18 KSA00969.1 - 2e-44 152.0 8.7 2.4e-44 151.8 8.7 1.0 1 0 0 1 1 1 1 BAR domain NPV_P10 PF05531.12 KSA00969.1 - 0.0027 18.2 5.2 0.2 12.2 0.4 3.1 3 0 0 3 3 3 2 Nucleopolyhedrovirus P10 protein Arfaptin PF06456.13 KSA00969.1 - 0.027 14.1 8.6 0.13 11.8 8.6 2.0 1 1 0 1 1 1 0 Arfaptin-like domain SLATT_5 PF18160.1 KSA00969.1 - 1.8 7.8 8.3 2.7 7.3 1.1 2.9 3 0 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain family 5 Jnk-SapK_ap_N PF09744.9 KSA00969.1 - 6.7 6.9 10.2 1.7 8.8 1.5 2.5 2 1 0 2 2 2 0 JNK_SAPK-associated protein-1 AMPKBI PF04739.15 KSA00970.1 - 2e-26 92.0 14.9 1.1e-24 86.4 14.9 3.5 2 1 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interaction domain AMPK1_CBM PF16561.5 KSA00970.1 - 1.3e-16 60.6 1.9 3.6e-16 59.1 0.3 2.4 3 0 0 3 3 3 1 Glycogen recognition site of AMP-activated protein kinase Glycoprotein_B PF00606.18 KSA00971.1 - 0.0021 17.6 1.0 0.0084 15.6 0.3 2.0 2 0 0 2 2 2 1 Herpesvirus Glycoprotein B ectodomain AAA PF00004.29 KSA00972.1 - 1.7e-53 180.5 0.1 1.7e-37 128.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 KSA00972.1 - 2.1e-10 41.0 2.8 9.5e-06 25.8 0.1 3.9 4 0 0 4 4 3 1 AAA domain (Cdc48 subfamily) AAA_lid_3 PF17862.1 KSA00972.1 - 5.6e-10 38.9 0.1 1.5e-09 37.5 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 KSA00972.1 - 2.6e-09 37.5 1.3 0.0019 18.4 0.1 3.9 2 2 0 3 3 3 2 AAA domain TIP49 PF06068.13 KSA00972.1 - 7.4e-08 32.0 0.1 0.0046 16.2 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_16 PF13191.6 KSA00972.1 - 8.7e-08 32.7 0.0 0.0091 16.4 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_18 PF13238.6 KSA00972.1 - 1.1e-07 32.4 0.1 0.0058 17.2 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_5 PF07728.14 KSA00972.1 - 1.5e-07 31.5 0.1 0.0031 17.5 0.0 2.9 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KSA00972.1 - 2.2e-07 30.8 0.1 0.021 14.6 0.0 2.7 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 KSA00972.1 - 3.5e-07 29.8 0.2 0.0054 16.1 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI CDC48_N PF02359.18 KSA00972.1 - 3.9e-06 27.0 0.0 9.1e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_33 PF13671.6 KSA00972.1 - 6.6e-06 26.3 0.0 0.15 12.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 KSA00972.1 - 8.6e-06 25.6 0.0 0.17 11.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 KSA00972.1 - 1.1e-05 25.2 0.0 0.039 13.7 0.0 2.6 3 0 0 3 3 2 2 IstB-like ATP binding protein AAA_7 PF12775.7 KSA00972.1 - 2.8e-05 23.7 0.0 0.034 13.7 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region RNA_helicase PF00910.22 KSA00972.1 - 7e-05 23.2 0.0 0.38 11.2 0.0 2.9 2 0 0 2 2 2 2 RNA helicase CDC48_2 PF02933.17 KSA00972.1 - 0.00017 21.3 1.4 0.0047 16.7 0.1 2.8 3 0 0 3 3 2 1 Cell division protein 48 (CDC48), domain 2 TsaE PF02367.17 KSA00972.1 - 0.00018 21.5 0.0 0.13 12.2 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 KSA00972.1 - 0.00025 20.7 0.7 0.6 9.6 0.0 3.3 4 0 0 4 4 3 2 AAA domain Sigma54_activat PF00158.26 KSA00972.1 - 0.00034 20.4 0.0 0.96 9.1 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_14 PF13173.6 KSA00972.1 - 0.00042 20.4 0.0 0.42 10.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 KSA00972.1 - 0.0005 20.6 0.2 0.099 13.2 0.1 2.5 2 0 0 2 2 2 1 ABC transporter AAA_11 PF13086.6 KSA00972.1 - 0.0005 19.9 0.0 0.8 9.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_3 PF07726.11 KSA00972.1 - 0.00051 19.9 0.0 0.22 11.4 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 KSA00972.1 - 0.00061 19.1 0.2 0.42 9.8 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 KSA00972.1 - 0.00064 19.2 0.0 1.2 8.5 0.0 2.6 2 0 0 2 2 2 2 PhoH-like protein NB-ARC PF00931.22 KSA00972.1 - 0.00075 18.7 0.0 0.44 9.7 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain TniB PF05621.11 KSA00972.1 - 0.001 18.6 0.2 6.3 6.2 0.0 3.8 3 1 0 4 4 4 0 Bacterial TniB protein AAA_28 PF13521.6 KSA00972.1 - 0.0013 19.0 0.0 2.1 8.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KSA00972.1 - 0.0013 19.1 0.0 0.69 10.2 0.0 2.9 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 KSA00972.1 - 0.002 17.5 0.2 0.9 8.8 0.0 3.0 2 1 0 2 2 2 1 KaiC AAA_17 PF13207.6 KSA00972.1 - 0.0036 17.7 0.1 1.1 9.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 KSA00972.1 - 0.0039 17.1 0.2 0.87 9.5 0.1 3.1 2 1 0 2 2 2 1 Rad17 P-loop domain AAA_30 PF13604.6 KSA00972.1 - 0.0039 16.9 0.0 1 9.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain Parvo_NS1 PF01057.17 KSA00972.1 - 0.0047 16.0 0.0 2.7 7.0 0.0 2.5 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 NACHT PF05729.12 KSA00972.1 - 0.0074 16.2 0.4 1.6 8.6 0.0 2.9 3 0 0 3 3 2 1 NACHT domain Zeta_toxin PF06414.12 KSA00972.1 - 0.013 14.8 0.0 0.34 10.2 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin Sigma54_activ_2 PF14532.6 KSA00972.1 - 0.019 15.1 0.1 11 6.1 0.0 2.9 2 1 0 2 2 2 0 Sigma-54 interaction domain Vps4_C PF09336.10 KSA00972.1 - 0.038 14.0 0.1 0.1 12.6 0.1 1.7 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain KTI12 PF08433.10 KSA00972.1 - 0.045 13.2 0.1 6 6.2 0.0 2.5 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Hydin_ADK PF17213.3 KSA00972.1 - 0.061 13.6 0.1 0.34 11.1 0.0 2.1 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain Cytidylate_kin PF02224.18 KSA00972.1 - 0.069 12.9 0.0 8.4 6.1 0.0 2.6 2 0 0 2 2 2 0 Cytidylate kinase DEAD PF00270.29 KSA00972.1 - 0.073 12.8 0.6 19 5.0 0.0 3.1 2 2 1 3 3 3 0 DEAD/DEAH box helicase CPT PF07931.12 KSA00972.1 - 0.11 12.3 0.2 0.45 10.3 0.0 1.9 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Torsin PF06309.11 KSA00972.1 - 0.13 12.4 0.0 11 6.2 0.0 2.7 2 0 0 2 2 2 0 Torsin AAA_29 PF13555.6 KSA00972.1 - 0.14 12.0 0.2 12 5.8 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain AhpC-TSA PF00578.21 KSA00973.1 - 2e-33 115.0 0.0 2.9e-33 114.4 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KSA00973.1 - 6.4e-17 61.6 0.0 8.3e-17 61.3 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 KSA00973.1 - 1.8e-13 50.1 0.0 4.3e-13 48.9 0.0 1.7 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 KSA00973.1 - 0.0017 18.3 0.1 0.0046 16.9 0.0 1.7 2 0 0 2 2 2 1 SCO1/SenC HIT PF01230.23 KSA00974.1 - 7.2e-22 78.0 0.2 1e-21 77.5 0.2 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KSA00974.1 - 0.00077 19.9 0.2 0.0012 19.3 0.2 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 KSA00974.1 - 0.05 13.5 0.1 0.092 12.6 0.1 1.4 1 1 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 Cu_bind_CorA PF18252.1 KSA00974.1 - 0.15 11.6 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Copper(I)-binding protein CorA Med6 PF04934.14 KSA00975.1 - 1.7e-51 173.5 1.5 2.5e-51 172.9 1.5 1.3 1 0 0 1 1 1 1 MED6 mediator sub complex component Pro_isomerase PF00160.21 KSA00976.1 - 7.8e-44 149.7 0.2 9.8e-44 149.4 0.2 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD IGR PF09597.10 KSA00977.1 - 1e-22 80.0 0.1 2.3e-22 78.8 0.1 1.6 1 0 0 1 1 1 1 IGR protein motif SAM_1 PF00536.30 KSA00977.1 - 0.068 13.6 0.1 0.11 13.0 0.1 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Ligase_CoA PF00549.19 KSA00978.1 - 4.3e-26 91.6 0.0 1.1e-25 90.2 0.0 1.7 2 0 0 2 2 2 1 CoA-ligase CoA_binding PF02629.19 KSA00978.1 - 1.7e-24 86.3 1.8 1.7e-24 86.3 1.8 2.1 2 0 0 2 2 2 1 CoA binding domain Succ_CoA_lig PF13607.6 KSA00978.1 - 5.6e-07 29.4 0.0 1e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 KSA00978.1 - 1.6e-05 25.4 0.1 4.2e-05 24.0 0.1 1.8 1 0 0 1 1 1 1 CoA binding domain Actin PF00022.19 KSA00979.1 - 1.6e-23 83.0 1.3 2.3e-18 66.0 0.0 3.3 3 1 0 3 3 3 2 Actin Actin_micro PF17003.5 KSA00979.1 - 1.6e-06 27.6 8.2 0.0016 17.7 0.1 3.2 3 0 0 3 3 3 2 Putative actin-like family MreB_Mbl PF06723.13 KSA00979.1 - 4.7e-06 25.7 0.1 3.7e-05 22.7 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 KSA00979.1 - 0.0061 17.0 0.0 0.014 15.8 0.0 1.7 1 0 0 1 1 1 1 Cell division protein FtsA NOA36 PF06524.12 KSA00979.1 - 5.6 6.2 8.5 13 5.0 8.5 1.6 1 0 0 1 1 1 0 NOA36 protein Syntaxin PF00804.25 KSA00980.1 - 0.041 13.5 3.4 0.098 12.3 3.4 1.6 1 0 0 1 1 1 0 Syntaxin DapB_C PF05173.14 KSA00980.1 - 0.11 12.5 0.0 0.33 11.0 0.0 1.8 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, C-terminus HP0268 PF18618.1 KSA00980.1 - 0.17 12.3 3.1 8.1 6.9 0.9 2.8 2 0 0 2 2 2 0 HP0268 Svf1 PF08622.10 KSA00981.1 - 6.1e-65 218.2 0.2 1.2e-64 217.3 0.2 1.5 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain Svf1_C PF17187.4 KSA00981.1 - 2.3e-64 216.2 1.6 1.1e-63 214.0 0.9 2.0 2 0 0 2 2 2 1 Svf1-like C-terminal lipocalin-like domain Peptidase_M16_C PF05193.21 KSA00982.1 - 2.2e-18 66.9 0.3 1.1e-14 54.8 0.0 3.3 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KSA00982.1 - 2.9e-09 37.1 0.0 1.3e-08 34.9 0.0 2.1 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) DUF2115 PF09888.9 KSA00982.1 - 2.2 8.8 6.7 0.42 11.1 0.9 2.7 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2115) UFD1 PF03152.14 KSA00983.1 - 5.7e-26 91.0 0.0 1.2e-25 90.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 AZUL PF16558.5 KSA00983.1 - 1.6e-05 25.0 0.2 1.6e-05 25.0 0.2 2.2 2 0 0 2 2 2 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A Ribosomal_S26e PF01283.19 KSA00983.1 - 1 9.8 3.9 0.3 11.5 0.3 1.9 2 0 0 2 2 2 0 Ribosomal protein S26e Peptidase_S8 PF00082.22 KSA00984.1 - 3.3e-32 111.9 9.3 5.8e-32 111.1 9.3 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KSA00984.1 - 4.1e-13 49.8 0.0 1e-12 48.5 0.0 1.7 1 0 0 1 1 1 1 Peptidase inhibitor I9 UQ_con PF00179.26 KSA00985.1 - 2.1e-25 89.0 0.1 2.4e-25 88.8 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Vpu PF00558.19 KSA00985.1 - 0.036 13.8 1.5 0.054 13.3 1.5 1.3 1 0 0 1 1 1 0 Vpu protein COX4 PF02936.14 KSA00986.1 - 9.6e-05 22.4 2.9 9.9e-05 22.4 0.1 2.3 2 1 0 2 2 2 1 Cytochrome c oxidase subunit IV GCIP PF13324.6 KSA00987.1 - 0.93 9.0 5.6 0.96 9.0 4.2 1.8 2 1 0 2 2 2 0 Grap2 and cyclin-D-interacting DUF3987 PF13148.6 KSA00987.1 - 1.1 8.2 2.6 1.7 7.6 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) BCDHK_Adom3 PF10436.9 KSA00988.1 - 3.9e-38 130.8 0.1 6e-38 130.2 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KSA00988.1 - 2.4e-07 31.2 0.0 1.3e-05 25.7 0.0 2.5 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KSA00988.1 - 0.00019 21.2 0.0 0.00039 20.3 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HUN PF08729.10 KSA00989.1 - 5.1e-08 32.8 0.4 5.1e-08 32.8 0.4 2.5 2 0 0 2 2 2 1 HPC2 and ubinuclein domain Kinetochor_Ybp2 PF08568.10 KSA00990.1 - 7.4e-150 500.5 28.9 9.4e-150 500.1 28.9 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin FERM_C PF09380.10 KSA00990.1 - 0.089 13.2 1.0 2.3 8.6 0.0 2.7 2 1 0 2 2 2 0 FERM C-terminal PH-like domain Bromo_TP_like PF17027.5 KSA00990.1 - 2.4 8.3 11.2 5.9 7.1 2.1 3.8 3 1 0 3 3 3 0 Histone-fold protein APG12 PF04110.13 KSA00991.1 - 4.9e-28 97.4 0.7 7.8e-28 96.7 0.7 1.3 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 SUN PF03856.13 KSA00992.1 - 5.8e-93 310.9 19.0 9e-93 310.2 19.0 1.3 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) zf-MYND PF01753.18 KSA00992.1 - 0.09 12.9 2.0 0.26 11.4 2.0 1.7 1 0 0 1 1 1 0 MYND finger Macoilin PF09726.9 KSA00992.1 - 0.36 9.4 8.1 0.47 9.0 8.1 1.1 1 0 0 1 1 1 0 Macoilin family Miga PF10265.9 KSA00992.1 - 5.6 5.8 5.7 7.3 5.4 5.7 1.1 1 0 0 1 1 1 0 Mitoguardin Pkinase PF00069.25 KSA00994.1 - 7.4e-46 156.6 0.6 1e-44 152.9 0.6 2.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KSA00994.1 - 8.9e-19 67.8 0.0 3e-18 66.0 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KSA00994.1 - 0.0024 17.3 0.0 0.0047 16.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KSA00994.1 - 0.21 10.9 0.9 0.75 9.0 0.1 2.2 3 0 0 3 3 3 0 Kinase-like zf-H2C2_2 PF13465.6 KSA00996.1 - 5.6e-10 39.2 18.1 8.2e-07 29.2 4.8 3.5 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 KSA00996.1 - 6.1e-09 35.8 21.8 0.0014 18.9 0.9 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KSA00996.1 - 1.6e-06 28.4 18.3 0.043 14.7 0.4 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.7 KSA00996.1 - 0.00055 20.2 6.7 0.17 12.3 0.4 3.6 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 KSA00996.1 - 0.035 14.0 0.9 0.089 12.7 0.9 1.7 1 0 0 1 1 1 0 zinc-finger of a C2HC-type zf-C2H2_3rep PF18868.1 KSA00996.1 - 0.12 13.0 7.1 4.3 8.0 1.1 3.5 1 1 2 3 3 3 0 Zinc finger C2H2-type, 3 repeats OSTMP1 PF09777.9 KSA00996.1 - 0.17 11.3 1.7 0.3 10.4 1.7 1.4 1 0 0 1 1 1 0 Osteopetrosis-associated transmembrane protein 1 precursor zf-C2H2_jaz PF12171.8 KSA00996.1 - 1 9.7 9.9 11 6.4 0.9 3.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.10 KSA00996.1 - 1.8 8.7 8.6 2.1 8.6 1.9 2.9 1 1 2 3 3 3 0 Zinc ribbon domain zinc-ribbons_6 PF07191.12 KSA00996.1 - 3.5 7.7 6.5 4.2e+02 1.0 5.9 2.8 1 1 0 1 1 1 0 zinc-ribbons zf-RRPl_C4 PF17026.5 KSA00996.1 - 3.7 7.7 7.2 1.6 8.8 3.9 2.1 2 1 0 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type C1_4 PF07975.12 KSA00996.1 - 8.4 6.7 9.0 48 4.3 3.4 2.5 1 1 0 2 2 2 0 TFIIH C1-like domain FYVE PF01363.21 KSA00996.1 - 9.5 6.5 10.1 17 5.6 4.7 2.4 1 1 1 2 2 2 0 FYVE zinc finger XRN_M PF17846.1 KSA00998.1 - 8.6e-87 291.9 8.6 8.6e-87 291.9 8.6 2.7 2 1 0 2 2 2 1 Xrn1 helical domain XRN_N PF03159.18 KSA00998.1 - 1.6e-78 263.5 0.2 1.6e-78 263.5 0.2 2.3 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus XRN1_D1 PF18332.1 KSA00998.1 - 1.5e-64 217.3 0.2 1.5e-64 217.3 0.2 2.5 2 0 0 2 2 2 1 Exoribonuclease Xrn1 D1 domain Xrn1_D3 PF18194.1 KSA00998.1 - 1.8e-29 101.6 0.7 6.7e-29 99.8 0.7 2.0 1 0 0 1 1 1 1 Exoribonuclease 1 Domain-3 XRN1_D2_D3 PF18334.1 KSA00998.1 - 3.5e-29 100.8 3.2 4.5e-29 100.5 0.0 2.8 3 0 0 3 3 3 1 Exoribonuclease Xrn1 D2/D3 domain SH3_12 PF18129.1 KSA00998.1 - 1.8e-14 53.6 0.0 3.4e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 Xrn1 SH3-like domain CHCH PF06747.13 KSA00999.1 - 0.0039 17.3 4.7 0.0065 16.6 4.7 1.4 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 KSA00999.1 - 0.11 12.5 5.8 0.28 11.2 5.5 1.7 1 1 1 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Pet191_N PF10203.9 KSA00999.1 - 0.23 11.8 5.8 1 9.7 5.8 1.9 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 Mito_carr PF00153.27 KSA01000.1 - 6.4e-75 247.2 0.3 7.9e-26 89.8 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 KSA01000.1 - 3.6e-05 24.1 1.6 0.31 11.5 0.0 4.2 4 0 0 4 4 4 1 EF-hand domain pair Serine_protease PF18405.1 KSA01000.1 - 0.092 11.9 0.3 0.7 9.0 0.0 2.4 2 1 1 3 3 3 0 Gammaproteobacterial serine protease EF-hand_6 PF13405.6 KSA01000.1 - 0.23 11.5 10.0 6.5 7.0 0.0 6.4 8 0 0 8 8 8 0 EF-hand domain EF-hand_1 PF00036.32 KSA01000.1 - 0.27 10.9 5.3 12 5.8 0.0 4.9 5 0 0 5 5 5 0 EF hand SIKE PF05769.11 KSA01001.1 - 0.0026 17.7 2.7 0.0081 16.1 2.7 1.9 1 0 0 1 1 1 1 SIKE family Cep57_CLD_2 PF14197.6 KSA01001.1 - 0.17 12.0 5.4 0.066 13.3 1.5 2.4 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 DUF4201 PF13870.6 KSA01001.1 - 1.1 8.9 13.4 0.31 10.8 7.5 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4201) Nucleoporin_FG PF13634.6 KSA01002.1 - 2.4e-36 124.5 170.1 5e-10 40.1 37.4 5.3 1 1 4 5 5 5 5 Nucleoporin FG repeat region DUF3453 PF11935.8 KSA01002.1 - 0.026 14.1 0.2 0.04 13.6 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3453) Bud13 PF09736.9 KSA01003.1 - 3.9e-36 124.6 5.2 3.9e-36 124.6 5.2 2.1 2 0 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex Cytadhesin_P30 PF07271.11 KSA01003.1 - 0.032 13.8 0.2 0.032 13.8 0.2 1.6 1 1 0 1 1 1 0 Cytadhesin P30/P32 Nop16 PF09420.10 KSA01003.1 - 0.85 9.6 16.9 4.6 7.2 16.9 2.1 1 1 0 1 1 1 0 Ribosome biogenesis protein Nop16 PUF PF00806.19 KSA01004.1 - 2.7e-52 171.6 30.1 3.2e-08 32.8 0.1 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat PriX PF18689.1 KSA01004.1 - 0.084 13.2 6.1 3.6 8.0 0.2 2.8 3 0 0 3 3 3 0 Primase X Sas10_Utp3 PF04000.15 KSA01005.1 - 2.1e-12 47.5 2.2 2.1e-12 47.5 2.2 2.7 3 0 0 3 3 3 1 Sas10/Utp3/C1D family Ribosomal_S8e PF01201.22 KSA01006.1 - 2.2e-44 150.9 0.0 3.7e-44 150.2 0.0 1.3 1 1 0 1 1 1 1 Ribosomal protein S8e HPD PF05044.12 KSA01006.1 - 0.41 10.5 2.5 0.28 11.1 0.2 1.7 2 0 0 2 2 2 0 Homeo-prospero domain Fungal_trans PF04082.18 KSA01007.1 - 8.1e-76 254.6 11.7 8.7e-76 254.5 10.1 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KSA01007.1 - 1.9e-05 24.9 2.6 1.9e-05 24.9 2.6 3.7 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KSA01007.1 - 0.01 16.6 1.5 0.01 16.6 1.5 4.1 5 0 0 5 5 5 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KSA01007.1 - 0.17 12.4 6.6 3 8.4 0.6 3.4 2 1 0 2 2 2 0 Zinc-finger double domain zf-RING_2 PF13639.6 KSA01008.1 - 1.3e-09 38.3 3.4 8.1e-08 32.5 0.8 2.4 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 KSA01008.1 - 6.3e-09 36.0 0.7 6.3e-09 36.0 0.7 2.5 2 1 1 3 3 3 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KSA01008.1 - 9.8e-08 31.7 4.0 2.8e-06 27.1 1.3 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KSA01008.1 - 6e-07 29.4 1.8 0.00028 20.9 0.2 2.6 2 0 0 2 2 2 2 RING-type zinc-finger zf-C3HC4 PF00097.25 KSA01008.1 - 9.2e-07 28.6 3.7 1e-05 25.3 0.9 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KSA01008.1 - 7.1e-05 22.6 1.1 0.0036 17.1 0.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KSA01008.1 - 0.00025 20.9 4.0 0.003 17.4 0.6 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-Nse PF11789.8 KSA01008.1 - 0.00056 19.7 2.7 0.0015 18.3 1.1 2.3 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-ANAPC11 PF12861.7 KSA01008.1 - 0.00064 19.7 0.6 0.0033 17.4 0.3 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 KSA01008.1 - 0.00075 19.4 3.3 0.0094 15.9 0.3 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_6 PF14835.6 KSA01008.1 - 0.003 17.4 0.2 0.49 10.3 0.1 2.8 2 0 0 2 2 2 1 zf-RING of BARD1-type protein Gemini_AL1_M PF08283.11 KSA01008.1 - 0.017 15.2 0.2 0.043 13.9 0.2 1.6 1 0 0 1 1 1 0 Geminivirus rep protein central domain zf-RING_11 PF17123.5 KSA01008.1 - 0.021 14.5 0.6 2.3 8.0 0.1 2.5 2 0 0 2 2 2 0 RING-like zinc finger Latarcin PF10279.9 KSA01008.1 - 0.067 13.6 3.5 0.24 11.8 2.0 2.3 2 0 0 2 2 2 0 Latarcin precursor Zn_ribbon_17 PF17120.5 KSA01008.1 - 0.083 12.5 0.7 0.2 11.3 0.7 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 KSA01008.1 - 0.55 10.4 8.1 0.068 13.3 1.4 2.3 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 KSA01008.1 - 0.82 9.9 5.6 0.81 9.9 0.5 2.8 2 1 0 2 2 2 0 FANCL C-terminal domain CDC37_M PF08565.11 KSA01009.1 - 1.1e-43 147.9 1.5 1.1e-43 147.9 1.5 3.0 4 0 0 4 4 4 1 Cdc37 Hsp90 binding domain CDC37_N PF03234.14 KSA01009.1 - 1.2e-43 149.2 7.4 1.2e-43 149.2 7.4 3.4 3 1 0 3 3 3 1 Cdc37 N terminal kinase binding CDC37_C PF08564.10 KSA01009.1 - 5.1e-23 81.1 3.3 5.1e-23 81.1 3.3 2.5 2 0 0 2 2 2 1 Cdc37 C terminal domain DUF4760 PF15956.5 KSA01009.1 - 0.19 11.9 4.8 2 8.5 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4760) TPR_4 PF07721.14 KSA01009.1 - 0.25 12.1 0.1 0.51 11.1 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat RRM_1 PF00076.22 KSA01010.1 - 5.1e-08 32.6 0.0 1.4e-07 31.2 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KSA01010.1 - 0.0015 18.2 0.0 0.0046 16.5 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GFO_IDH_MocA PF01408.22 KSA01011.1 - 1e-16 61.9 0.3 2.8e-15 57.2 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KSA01011.1 - 1e-07 31.9 0.0 1.9e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Sec20 PF03908.13 KSA01012.1 - 8.1e-28 96.2 3.1 8.1e-28 96.2 3.1 2.5 3 0 0 3 3 3 1 Sec20 LMBR1 PF04791.16 KSA01012.1 - 0.069 12.1 7.3 0.083 11.8 7.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Exo_endo_phos PF03372.23 KSA01013.1 - 2.7e-24 86.0 0.0 4.7e-24 85.2 0.0 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Mob1_phocein PF03637.17 KSA01014.1 - 8.9e-72 240.6 0.5 1.1e-71 240.2 0.5 1.1 1 0 0 1 1 1 1 Mob1/phocein family DUF5072 PF16807.5 KSA01014.1 - 0.11 12.6 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5072) CDC45 PF02724.14 KSA01018.1 - 0.17 10.1 7.0 0.22 9.8 7.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Fe-S_biosyn PF01521.20 KSA01019.1 - 3.5e-20 72.3 0.0 5.6e-20 71.6 0.0 1.3 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis RR_TM4-6 PF06459.12 KSA01019.1 - 0.25 11.2 8.6 0.3 10.9 8.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 KSA01019.1 - 4.3 6.0 4.5 4.8 5.8 4.5 1.1 1 0 0 1 1 1 0 Presenilin Creatinase_N_2 PF16189.5 KSA01020.1 - 3.4e-48 163.8 1.3 4.9e-48 163.3 0.4 1.7 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 KSA01020.1 - 5.4e-38 130.8 0.0 7.8e-38 130.3 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 KSA01020.1 - 3.8e-23 81.3 1.4 9.9e-23 80.0 1.4 1.8 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 KSA01020.1 - 4.1e-16 59.8 0.0 1.2e-10 42.1 0.0 2.3 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain Xpo1 PF08389.12 KSA01021.1 - 0.077 13.1 9.8 0.047 13.8 1.8 3.7 3 0 0 3 3 3 0 Exportin 1-like protein Rep_fac-A_C PF08646.10 KSA01022.1 - 7.2e-58 194.5 6.2 2e-54 183.3 5.3 2.5 2 0 0 2 2 2 2 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 KSA01022.1 - 7.3e-35 118.8 0.2 7.1e-33 112.4 0.0 3.3 3 0 0 3 3 3 1 Replication protein A OB domain tRNA_anti-codon PF01336.25 KSA01022.1 - 1.1e-11 44.6 0.2 8.1e-08 32.2 0.0 4.5 5 0 0 5 5 5 1 OB-fold nucleic acid binding domain Rep-A_N PF04057.12 KSA01022.1 - 2.9e-10 40.1 0.1 7.6e-10 38.7 0.1 1.8 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain CDC24_OB3 PF17244.2 KSA01022.1 - 0.00032 20.5 0.0 0.0026 17.5 0.0 2.4 2 1 0 2 2 2 1 Cell division control protein 24, OB domain 3 DUF4539 PF15072.6 KSA01022.1 - 0.00055 19.9 0.0 1.2 9.2 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4539) TPP1 PF10341.9 KSA01022.1 - 0.0021 18.0 0.4 0.019 15.0 0.1 2.7 2 0 0 2 2 2 1 Shelterin complex subunit, TPP1/ACD DUF223 PF02721.14 KSA01022.1 - 0.0054 17.0 0.1 0.018 15.4 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function DUF223 Mut7-C PF01927.16 KSA01022.1 - 0.082 13.0 0.8 0.29 11.2 0.8 1.9 1 0 0 1 1 1 0 Mut7-C RNAse domain Cys_Met_Meta_PP PF01053.20 KSA01023.1 - 1.9e-135 451.3 0.0 2.2e-135 451.1 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KSA01023.1 - 5.9e-05 22.5 0.0 0.0015 17.9 0.0 2.6 2 1 1 3 3 3 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 KSA01023.1 - 0.00068 18.9 0.0 0.0013 18.0 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KSA01023.1 - 0.00099 18.2 0.1 0.0032 16.5 0.1 1.8 2 0 0 2 2 2 1 Aminotransferase class-V ZFYVE21_C PF16696.5 KSA01023.1 - 0.048 13.5 0.2 0.11 12.3 0.0 1.7 2 0 0 2 2 2 0 Zinc finger FYVE domain-containing protein 21 C-terminus GDC-P PF02347.16 KSA01023.1 - 0.05 12.4 0.0 0.08 11.8 0.0 1.3 1 0 0 1 1 1 0 Glycine cleavage system P-protein 2Fe-2S_thioredx PF01257.19 KSA01024.1 - 3.5e-61 205.3 0.3 4.5e-61 204.9 0.3 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Asp PF00026.23 KSA01025.1 - 6.6e-26 91.5 4.1 3.7e-24 85.7 4.1 2.1 1 1 0 1 1 1 1 Eukaryotic aspartyl protease WD40 PF00400.32 KSA01026.1 - 3.5e-21 75.1 18.7 0.00097 19.9 0.0 7.1 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KSA01026.1 - 4.6e-16 58.9 7.6 7.3e-07 29.4 0.6 4.3 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KSA01026.1 - 7.9e-07 29.1 3.0 0.7 9.7 0.1 3.3 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KSA01026.1 - 0.014 14.4 0.0 0.082 11.8 0.0 2.1 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF3130 PF11328.8 KSA01026.1 - 0.11 12.7 0.3 0.27 11.5 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3130 Aminotran_1_2 PF00155.21 KSA01027.1 - 6.2e-22 78.3 0.0 7.9e-22 77.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KSA01027.1 - 0.0051 16.1 0.0 0.0067 15.7 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_MocR PF12897.7 KSA01027.1 - 0.14 10.9 0.0 0.21 10.3 0.0 1.2 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase WD40 PF00400.32 KSA01028.1 - 4.4e-25 87.4 13.4 9.7e-08 32.6 0.1 7.0 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KSA01028.1 - 5e-15 55.6 0.0 0.0063 16.8 0.0 6.2 3 1 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Hira PF07569.11 KSA01028.1 - 2.1e-12 47.3 1.3 3.9e-12 46.4 0.0 2.2 3 0 0 3 3 3 1 TUP1-like enhancer of split HIRA_B PF09453.10 KSA01028.1 - 4.4e-11 42.3 1.2 9.3e-11 41.3 1.2 1.6 1 0 0 1 1 1 1 HIRA B motif PD40 PF07676.12 KSA01028.1 - 8.7e-08 31.9 0.2 0.21 11.5 0.1 4.6 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat eIF2A PF08662.11 KSA01028.1 - 0.00048 20.1 0.1 0.019 14.9 0.0 3.5 5 0 0 5 5 5 1 Eukaryotic translation initiation factor eIF2A Reg_prop PF07494.11 KSA01028.1 - 0.031 14.5 1.0 17 6.1 0.1 4.3 3 0 0 3 3 3 0 Two component regulator propeller Ge1_WD40 PF16529.5 KSA01028.1 - 0.073 12.0 0.1 22 3.9 0.0 3.6 2 1 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein CHD5 PF04420.14 KSA01029.1 - 6.1e-52 175.7 1.5 9.7e-52 175.0 1.5 1.3 1 0 0 1 1 1 1 CHD5-like protein CK_II_beta PF01214.18 KSA01030.1 - 4.3e-66 222.2 0.0 5.4e-66 221.9 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit HSCB_C PF07743.13 KSA01031.1 - 7.2e-18 64.9 8.2 1.5e-17 63.9 8.2 1.5 1 0 0 1 1 1 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 KSA01031.1 - 2.1e-05 24.5 0.9 0.00054 20.0 0.0 3.1 1 1 2 3 3 3 1 DnaJ domain Mis12 PF05859.12 KSA01031.1 - 0.029 14.4 1.9 5.3 7.1 0.0 2.2 1 1 1 2 2 2 0 Mis12 protein zf-CCCH PF00642.24 KSA01032.1 - 5.5e-10 38.9 1.2 1.1e-09 38.0 1.2 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KSA01032.1 - 5.9e-07 29.3 3.6 1.2e-06 28.4 3.6 1.6 1 0 0 1 1 1 1 Zinc finger domain zf-C3HC4_3 PF13920.6 KSA01032.1 - 1.4e-06 28.0 6.4 3e-06 27.0 6.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KSA01032.1 - 2.7e-05 24.0 11.6 5.6e-05 22.9 11.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KSA01032.1 - 4.9e-05 23.6 8.2 0.00011 22.4 8.2 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KSA01032.1 - 6.5e-05 22.8 10.4 0.00013 21.9 10.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KSA01032.1 - 8.3e-05 22.4 9.6 8.3e-05 22.4 9.6 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KSA01032.1 - 0.00043 20.1 6.3 0.00086 19.1 6.3 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KSA01032.1 - 0.00048 20.1 9.4 0.0013 18.7 9.4 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-CCCH_4 PF18044.1 KSA01032.1 - 0.00082 19.1 1.3 0.0016 18.2 1.3 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger zf-C3HC4_4 PF15227.6 KSA01032.1 - 0.011 15.8 8.5 0.011 15.8 8.5 2.4 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-CCCH_2 PF14608.6 KSA01032.1 - 0.088 13.3 1.7 0.088 13.3 1.7 2.1 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger zf-RING_10 PF16685.5 KSA01032.1 - 0.35 11.0 12.1 0.18 11.9 8.2 2.2 2 0 0 2 2 2 0 zinc RING finger of MSL2 DUF4112 PF13430.6 KSA01033.1 - 8e-23 80.7 0.3 1.1e-22 80.3 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) CTP_transf_like PF01467.26 KSA01034.1 - 2.8e-26 92.4 0.0 4.2e-16 59.4 0.0 2.2 2 0 0 2 2 2 2 Cytidylyltransferase-like FAD_syn PF06574.12 KSA01034.1 - 0.0031 17.4 0.0 0.97 9.3 0.0 2.3 2 0 0 2 2 2 2 FAD synthetase HABP4_PAI-RBP1 PF04774.15 KSA01035.1 - 0.00092 20.0 0.6 0.0014 19.5 0.6 1.3 1 0 0 1 1 1 1 Hyaluronan / mRNA binding family ATE_C PF04377.15 KSA01036.1 - 1.2e-49 168.4 0.0 2.1e-49 167.6 0.0 1.4 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 KSA01036.1 - 1.7e-27 95.6 3.0 3.6e-27 94.6 3.0 1.6 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus Acetyltransf_6 PF13480.7 KSA01036.1 - 0.2 11.8 0.1 0.56 10.3 0.1 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain TFIIF_beta_N PF17683.1 KSA01037.1 - 2.2e-39 135.2 2.5 2.2e-39 135.2 2.5 2.5 3 1 0 3 3 3 1 TFIIF, beta subunit N-terminus TFIIF_beta PF02270.15 KSA01037.1 - 1.7e-29 101.7 0.5 6.3e-29 99.9 0.6 2.0 2 0 0 2 2 2 1 TFIIF, beta subunit HTH domain Tau95 PF09734.9 KSA01037.1 - 0.56 11.0 11.8 0.31 11.9 6.8 2.8 2 1 0 2 2 2 0 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Ribosomal_L38e PF01781.18 KSA01038.1 - 5.1e-29 100.2 3.2 5.8e-29 100.0 3.2 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family Viral_Hsp90 PF03225.14 KSA01038.1 - 0.013 14.1 0.2 0.014 14.0 0.2 1.0 1 0 0 1 1 1 0 Viral heat shock protein Hsp90 homologue COG2 PF06148.11 KSA01038.1 - 0.05 13.7 0.3 0.055 13.6 0.3 1.0 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Prp18 PF02840.15 KSA01039.1 - 1.8e-46 157.7 2.7 1.8e-46 157.7 2.7 2.0 2 1 0 2 2 2 1 Prp18 domain Pex24p PF06398.11 KSA01040.1 - 8.9e-105 350.7 14.5 8.9e-105 350.7 14.5 1.7 2 0 0 2 2 2 1 Integral peroxisomal membrane peroxin Wzy_C PF04932.15 KSA01040.1 - 5.7 6.6 10.4 5.1e+02 0.2 10.5 2.4 1 1 0 1 1 1 0 O-Antigen ligase Uricase PF01014.18 KSA01041.1 - 3.8e-63 211.6 1.6 8.9e-34 116.6 1.0 2.0 2 0 0 2 2 2 2 Uricase EutQ PF06249.12 KSA01041.1 - 0.033 14.0 0.0 0.068 12.9 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ ThiF PF00899.21 KSA01042.1 - 3.2e-46 157.7 0.0 4.9e-46 157.1 0.0 1.2 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 KSA01042.1 - 0.0016 18.7 4.4 0.0076 16.5 1.2 3.0 3 1 0 3 3 3 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 KSA01042.1 - 0.0055 16.8 0.1 0.012 15.7 0.1 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 KSA01042.1 - 0.066 13.5 0.0 0.16 12.2 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 KSA01042.1 - 0.071 12.7 0.4 0.15 11.6 0.4 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF637 PF04830.13 KSA01042.1 - 0.14 12.0 0.3 0.28 11.0 0.1 1.6 1 1 0 1 1 1 0 Possible hemagglutinin (DUF637) DUF1279 PF06916.13 KSA01043.1 - 5.2e-33 113.4 0.1 1.1e-32 112.4 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) CagS PF16707.5 KSA01043.1 - 0.048 13.7 0.1 0.079 13.0 0.1 1.3 1 0 0 1 1 1 0 Cag pathogenicity island protein S of Helicobacter pylori Mito_carr PF00153.27 KSA01044.1 - 1.3e-58 194.9 3.6 1.1e-21 76.6 0.0 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KSA01044.1 - 6.9e-05 22.1 0.0 0.23 10.6 0.0 2.3 2 0 0 2 2 2 2 Gammaproteobacterial serine protease NDT80_PhoG PF05224.12 KSA01045.1 - 3.5e-66 223.0 0.2 3.5e-66 223.0 0.2 2.2 2 0 0 2 2 2 1 NDT80 / PhoG like DNA-binding family TALPID3 PF15324.6 KSA01045.1 - 0.011 13.5 11.6 0.015 13.1 11.6 1.1 1 0 0 1 1 1 0 Hedgehog signalling target Exonuc_VII_L PF02601.15 KSA01045.1 - 0.013 15.1 8.0 0.018 14.6 8.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Cob_adeno_trans PF01923.18 KSA01045.1 - 0.48 10.5 3.5 0.76 9.9 3.5 1.4 1 0 0 1 1 1 0 Cobalamin adenosyltransferase Zip PF02535.22 KSA01045.1 - 0.91 8.7 9.8 1.1 8.4 9.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter TFIIA PF03153.13 KSA01045.1 - 2 8.4 16.7 2.7 7.9 16.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-C2HE PF16278.5 KSA01046.1 - 0.0064 16.9 0.7 0.013 15.9 0.1 1.9 2 0 0 2 2 2 1 C2HE / C2H2 / C2HC zinc-binding finger zf-H2C2_2 PF13465.6 KSA01046.1 - 0.024 15.1 0.2 3.2 8.3 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2 PF00096.26 KSA01046.1 - 0.038 14.4 0.3 0.093 13.2 0.3 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KSA01046.1 - 1.1 10.3 3.1 0.55 11.2 0.5 1.9 2 0 0 2 2 2 0 C2H2-type zinc finger PET117 PF15786.5 KSA01047.1 - 3.8e-25 87.9 0.1 4.6e-25 87.7 0.1 1.1 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial Cyclin PF08613.11 KSA01048.1 - 2.4e-40 138.5 0.4 2.4e-40 138.5 0.4 2.4 2 1 0 2 2 2 1 Cyclin CENP-B_dimeris PF09026.10 KSA01048.1 - 0.064 13.7 0.4 0.064 13.7 0.4 2.5 3 0 0 3 3 3 0 Centromere protein B dimerisation domain DUF4820 PF16091.5 KSA01048.1 - 1.5 8.2 9.2 3.8 6.8 1.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) DUF4611 PF15387.6 KSA01048.1 - 9.9 6.5 13.9 0.6 10.4 5.8 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) Ribonuc_L-PSP PF01042.21 KSA01050.1 - 8.2e-11 42.0 0.0 8.4e-11 41.9 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Eclosion PF04736.12 KSA01050.1 - 0.14 11.8 0.0 0.16 11.7 0.0 1.1 1 0 0 1 1 1 0 Eclosion hormone WD40 PF00400.32 KSA01052.1 - 7e-10 39.3 3.1 0.038 14.9 0.1 5.8 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KSA01052.1 - 0.00015 22.0 0.3 2.3 8.6 0.0 3.9 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain SRA1 PF07304.11 KSA01052.1 - 0.00017 21.4 0.0 0.00017 21.4 0.0 3.4 3 0 0 3 3 3 1 Steroid receptor RNA activator (SRA1) Glyco_hydro_65m PF03632.15 KSA01053.1 - 3.2e-38 131.6 0.3 1.2e-29 103.3 1.4 2.4 1 1 1 2 2 2 2 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65N PF03636.15 KSA01053.1 - 2.1e-25 89.7 0.0 3.4e-25 89.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain F5_F8_type_C PF00754.25 KSA01053.1 - 0.00081 19.5 0.2 0.0025 17.9 0.2 1.8 1 0 0 1 1 1 1 F5/8 type C domain MIS13 PF08202.11 KSA01054.1 - 2.1e-86 289.9 17.3 2.1e-86 289.9 17.3 2.3 2 1 0 2 2 2 1 Mis12-Mtw1 protein family MRP-S33 PF08293.11 KSA01056.1 - 1.3e-31 108.7 0.2 1.5e-31 108.5 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 Ion_trans PF00520.31 KSA01057.1 - 1.3e-123 411.0 116.5 2.1e-36 125.4 22.5 5.2 5 0 0 5 5 5 5 Ion transport protein EF-hand_7 PF13499.6 KSA01057.1 - 0.019 15.4 0.0 0.059 13.8 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair GPHH PF16905.5 KSA01057.1 - 0.023 14.4 0.0 0.054 13.3 0.0 1.6 1 0 0 1 1 1 0 Voltage-dependent L-type calcium channel, IQ-associated EF-hand_6 PF13405.6 KSA01057.1 - 0.046 13.7 0.0 0.26 11.3 0.0 2.4 1 0 0 1 1 1 0 EF-hand domain zf-ZPR1 PF03367.13 KSA01058.1 - 2.3e-115 381.8 1.1 9.1e-57 191.4 0.2 2.3 2 0 0 2 2 2 2 ZPR1 zinc-finger domain HypA PF01155.19 KSA01058.1 - 0.00045 20.2 7.8 0.23 11.5 3.8 3.2 2 1 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA HSCB_C PF07743.13 KSA01058.1 - 0.015 15.8 0.1 0.49 10.9 0.1 2.9 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain SF-assemblin PF06705.11 KSA01058.1 - 0.027 13.8 0.9 0.061 12.7 0.1 2.0 2 0 0 2 2 2 0 SF-assemblin/beta giardin ESSS PF10183.9 KSA01058.1 - 0.037 14.2 0.1 8.4 6.7 0.0 2.5 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DZR PF12773.7 KSA01058.1 - 0.062 13.3 6.4 2.9 8.0 1.3 3.4 3 0 0 3 3 3 0 Double zinc ribbon GAT PF03127.14 KSA01058.1 - 0.068 13.5 0.1 0.23 11.8 0.1 1.9 1 0 0 1 1 1 0 GAT domain OrfB_Zn_ribbon PF07282.11 KSA01058.1 - 0.67 9.9 4.8 14 5.7 0.0 3.1 2 1 1 3 3 3 0 Putative transposase DNA-binding domain DUF3716 PF12511.8 KSA01058.1 - 2.2 8.4 5.4 31 4.7 2.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3716) Rubredoxin_2 PF18073.1 KSA01058.1 - 6.4 6.6 8.5 4.3 7.1 0.3 3.0 3 0 0 3 3 3 0 Rubredoxin metal binding domain zf-C4pol PF14260.6 KSA01058.1 - 6.5 7.3 10.8 2.3 8.7 0.6 3.6 2 2 1 3 3 3 0 C4-type zinc-finger of DNA polymerase delta WD40 PF00400.32 KSA01059.1 - 1.6e-40 136.4 27.9 4.3e-07 30.5 0.0 9.0 9 0 0 9 9 9 6 WD domain, G-beta repeat Nup160 PF11715.8 KSA01059.1 - 2.5e-13 49.5 13.6 0.0036 16.0 0.2 6.2 2 1 4 6 6 6 5 Nucleoporin Nup120/160 F-box-like PF12937.7 KSA01059.1 - 4.2e-12 45.8 1.4 9.1e-12 44.7 1.4 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KSA01059.1 - 3.7e-10 39.4 1.4 8.4e-10 38.3 1.4 1.7 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 KSA01059.1 - 2.1e-07 31.1 2.6 0.041 14.2 0.0 5.2 2 2 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 KSA01059.1 - 5.3e-07 29.6 0.0 0.0032 17.5 0.0 3.9 3 1 2 5 5 5 1 Ciliary BBSome complex subunit 2, middle region WD40_like PF17005.5 KSA01059.1 - 5.3e-05 22.7 0.3 0.00028 20.3 0.1 2.0 2 0 0 2 2 2 1 WD40-like domain Ge1_WD40 PF16529.5 KSA01059.1 - 0.0026 16.8 4.6 0.61 9.0 0.0 4.2 2 2 2 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein F-box_4 PF15966.5 KSA01059.1 - 0.0031 17.4 0.0 0.013 15.4 0.0 2.1 1 0 0 1 1 1 1 F-box eIF2A PF08662.11 KSA01059.1 - 0.007 16.3 0.4 2.7 7.8 0.0 2.9 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A CBM_21 PF03370.13 KSA01060.1 - 7.3e-38 129.2 0.4 7.3e-38 129.2 0.4 1.9 2 0 0 2 2 2 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 KSA01060.1 - 0.019 15.5 1.6 0.019 15.5 1.6 3.6 3 1 0 3 3 3 0 Starch/carbohydrate-binding module (family 53) DUF3910 PF13049.6 KSA01060.1 - 0.098 13.0 0.6 0.27 11.6 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3910) LCM PF04072.14 KSA01061.1 - 1.1e-20 74.4 0.0 1.7e-20 73.8 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Kelch_3 PF13415.6 KSA01061.1 - 1.5e-09 37.9 0.0 0.00028 21.1 0.0 4.0 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.6 KSA01061.1 - 3e-08 33.5 0.0 0.048 13.7 0.0 4.3 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.6 KSA01061.1 - 4.2e-08 33.1 0.0 0.0002 21.3 0.0 3.7 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.6 KSA01061.1 - 1.4e-07 31.5 4.5 0.35 11.2 0.0 4.9 4 1 1 5 5 5 3 Kelch motif Kelch_2 PF07646.15 KSA01061.1 - 6.7e-07 29.0 0.0 0.37 10.9 0.0 3.8 3 0 0 3 3 3 3 Kelch motif KH_6 PF15985.5 KSA01062.1 - 8.1e-14 51.7 0.1 1.6e-13 50.8 0.1 1.4 1 0 0 1 1 1 1 KH domain Rrp40_N PF18311.1 KSA01062.1 - 4.2e-10 39.4 0.1 9.3e-10 38.3 0.1 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease Rrp40 N-terminal domain oligo_HPY PF08352.12 KSA01062.1 - 0.17 12.4 0.1 0.63 10.6 0.1 2.0 3 0 0 3 3 3 0 Oligopeptide/dipeptide transporter, C-terminal region HORMA PF02301.18 KSA01063.1 - 2.2e-51 174.5 0.2 4.2e-51 173.5 0.2 1.5 1 0 0 1 1 1 1 HORMA domain PHD_2 PF13831.6 KSA01063.1 - 0.0015 18.1 9.8 0.1 12.2 7.8 2.6 2 0 0 2 2 2 2 PHD-finger PHD PF00628.29 KSA01063.1 - 0.048 13.6 9.6 0.3 11.0 8.1 2.5 2 0 0 2 2 2 0 PHD-finger Cytomega_TRL10 PF06084.11 KSA01063.1 - 1.5 8.8 4.3 13 5.8 2.1 2.8 3 0 0 3 3 3 0 Cytomegalovirus TRL10 protein AATase PF07247.12 KSA01064.1 - 8e-107 357.8 1.4 9.3e-107 357.6 1.4 1.0 1 0 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.20 KSA01064.1 - 1.1e-05 24.3 0.0 0.0049 15.6 0.1 2.2 2 0 0 2 2 2 2 Condensation domain WES_acyltransf PF03007.16 KSA01064.1 - 0.1 12.3 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain Toxin_14 PF07829.11 KSA01064.1 - 0.16 11.9 0.3 0.29 11.1 0.3 1.3 1 0 0 1 1 1 0 Alpha-A conotoxin PIVA-like protein APH PF01636.23 KSA01066.1 - 4.1e-08 33.4 0.0 6.1e-07 29.6 0.0 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KSA01066.1 - 0.055 12.8 0.0 0.14 11.5 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sedlin_N PF04628.13 KSA01067.1 - 5.1e-47 159.3 0.1 6.4e-47 159.0 0.1 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 KSA01067.1 - 0.00079 19.4 0.5 0.0031 17.4 0.2 2.2 2 1 0 2 2 2 1 Sybindin-like family Porin_7 PF16956.5 KSA01067.1 - 0.017 14.8 1.9 0.02 14.6 1.5 1.4 1 1 0 1 1 1 0 Putative general bacterial porin Nop16 PF09420.10 KSA01068.1 - 0.02 14.9 2.3 0.036 14.1 2.3 1.5 1 0 0 1 1 1 0 Ribosome biogenesis protein Nop16 Med22 PF06179.12 KSA01069.1 - 1.9e-16 60.2 1.3 2.3e-16 59.9 1.3 1.2 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex LAGLIDADG_1 PF00961.19 KSA01069.1 - 0.25 12.4 1.7 19 6.3 0.3 2.1 1 1 1 2 2 2 0 LAGLIDADG endonuclease DAHP_synth_1 PF00793.20 KSA01070.1 - 9.4e-14 50.9 0.0 1.6e-12 46.8 0.0 2.1 2 0 0 2 2 2 2 DAHP synthetase I family Baculo_PEP_C PF04513.12 KSA01071.1 - 0.2 11.7 3.7 0.5 10.4 3.7 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DSPc PF00782.20 KSA01072.1 - 5.4e-07 29.5 0.0 1.3e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KSA01072.1 - 7.7e-07 28.9 0.5 7e-06 25.8 0.0 2.3 2 1 1 3 3 3 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 KSA01072.1 - 0.00026 20.7 0.0 0.00046 19.9 0.0 1.4 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase3 PF13350.6 KSA01072.1 - 0.053 13.5 0.0 0.077 12.9 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family OGG_N PF07934.12 KSA01072.1 - 0.067 13.3 0.1 0.15 12.2 0.1 1.7 1 1 0 1 1 1 0 8-oxoguanine DNA glycosylase, N-terminal domain DM13 PF10517.9 KSA01072.1 - 0.11 13.1 0.0 0.26 11.9 0.0 1.7 1 0 0 1 1 1 0 Electron transfer DM13 TPR_1 PF00515.28 KSA01073.1 - 5.9e-24 82.8 17.6 3.3e-06 26.7 0.1 9.7 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_2 PF07719.17 KSA01073.1 - 4.4e-23 79.5 24.4 2.1e-05 24.3 0.1 11.0 12 0 0 12 12 11 6 Tetratricopeptide repeat TPR_8 PF13181.6 KSA01073.1 - 1.2e-17 62.6 21.0 0.0013 18.8 0.0 10.5 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_19 PF14559.6 KSA01073.1 - 1.9e-15 57.1 7.3 6.1e-06 26.7 0.0 5.5 4 2 1 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 KSA01073.1 - 1.9e-14 54.0 0.4 0.0041 17.7 0.0 6.1 4 1 2 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 KSA01073.1 - 2.6e-14 52.6 16.2 7.2e-05 22.4 0.0 8.0 7 2 2 9 9 9 4 TPR repeat TPR_12 PF13424.6 KSA01073.1 - 1.1e-13 51.3 9.0 0.07 13.4 0.3 7.4 6 1 1 7 7 7 5 Tetratricopeptide repeat TPR_17 PF13431.6 KSA01073.1 - 4.4e-13 48.6 6.3 0.015 15.6 0.0 7.3 8 0 0 8 8 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 KSA01073.1 - 1.1e-09 38.3 4.2 0.089 13.7 0.0 7.2 8 3 3 11 11 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KSA01073.1 - 3e-06 27.4 10.6 0.055 13.7 0.1 5.1 4 2 2 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_21 PF09976.9 KSA01073.1 - 1.9e-05 24.5 18.1 0.3 10.8 0.1 5.0 4 1 1 5 5 5 4 Tetratricopeptide repeat-like domain TPR_9 PF13371.6 KSA01073.1 - 0.00038 20.5 0.1 4.5 7.5 0.0 4.8 2 1 4 6 6 6 1 Tetratricopeptide repeat AP3D1 PF06375.11 KSA01073.1 - 0.0024 18.1 3.3 0.0068 16.7 3.3 1.8 1 0 0 1 1 1 1 AP-3 complex subunit delta-1 TPR_20 PF14561.6 KSA01073.1 - 0.0037 17.6 0.4 39 4.7 0.0 4.7 3 1 1 4 4 4 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 KSA01073.1 - 0.0042 16.7 0.3 0.2 11.3 0.3 3.0 1 1 1 3 3 3 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_MalT PF17874.1 KSA01073.1 - 0.02 14.3 1.5 3.1 7.1 0.3 2.7 1 1 0 3 3 3 0 MalT-like TPR region TPR_6 PF13174.6 KSA01073.1 - 0.022 15.3 11.1 1.1 10.0 0.0 7.0 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 KSA01073.1 - 0.031 14.3 8.2 4.3 7.6 0.0 6.0 8 0 0 8 8 6 0 Tetratricopeptide repeat TOM20_plant PF06552.12 KSA01073.1 - 0.075 12.8 0.1 0.075 12.8 0.1 4.1 4 0 0 4 4 4 0 Plant specific mitochondrial import receptor subunit TOM20 DUF4810 PF16068.5 KSA01073.1 - 0.27 11.8 5.3 11 6.7 0.0 4.2 2 1 2 4 4 4 0 Domain of unknown function (DUF4810) Arrestin_N PF00339.29 KSA01074.1 - 1.4e-09 38.2 2.4 2.7e-05 24.3 0.1 3.3 3 1 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain FKBP_C PF00254.28 KSA01075.1 - 1.6e-33 114.9 0.0 1.9e-33 114.6 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Foie-gras_1 PF11817.8 KSA01076.1 - 3.2e-10 40.0 0.2 8.4e-10 38.7 0.0 1.7 2 0 0 2 2 2 1 Foie gras liver health family 1 DUF745 PF05335.13 KSA01076.1 - 0.3 10.8 0.4 0.53 10.0 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF745) FeS_assembly_P PF01883.19 KSA01077.1 - 1.1e-07 31.9 0.0 3.1e-07 30.5 0.0 1.7 1 1 0 1 1 1 1 Iron-sulfur cluster assembly protein NT-C2 PF10358.9 KSA01079.1 - 1.2e-37 128.9 7.1 2e-37 128.1 7.1 1.4 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins GRP PF07172.11 KSA01081.1 - 0.75 10.5 21.6 0.91 10.3 21.6 1.2 1 0 0 1 1 1 0 Glycine rich protein family Glycogen_syn PF05693.13 KSA01082.1 - 0 1125.6 0.0 0 1125.3 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.20 KSA01082.1 - 1.5e-06 27.9 0.0 8.8e-05 22.1 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KSA01082.1 - 2.4e-06 28.0 0.0 0.0041 17.6 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KSA01082.1 - 3.3e-06 27.6 0.1 6.7e-06 26.6 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 KSA01082.1 - 9.3e-06 25.7 0.4 1.8e-05 24.8 0.4 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_transf_5 PF08323.11 KSA01082.1 - 7.9e-05 22.5 0.1 0.00018 21.3 0.1 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain WD40 PF00400.32 KSA01083.1 - 1.5e-45 152.3 16.3 3e-08 34.2 0.1 11.6 12 0 0 12 12 12 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KSA01083.1 - 1.9e-31 108.2 0.0 6.9e-05 23.1 0.0 9.2 5 2 4 10 10 10 8 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 KSA01083.1 - 1.6e-23 83.1 0.2 2.6e-23 82.4 0.2 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Ge1_WD40 PF16529.5 KSA01083.1 - 5.7e-07 28.8 1.0 0.11 11.4 0.0 5.8 5 3 2 7 7 7 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KSA01083.1 - 4.4e-06 26.3 4.6 0.051 12.9 0.0 5.4 4 1 2 6 6 6 2 WD40-like domain Nbas_N PF15492.6 KSA01083.1 - 4.9e-06 26.1 1.9 3.3 6.9 0.0 5.6 4 2 1 5 5 5 2 Neuroblastoma-amplified sequence, N terminal WD40_3 PF15911.5 KSA01083.1 - 6.1e-05 22.9 0.1 0.00027 20.9 0.0 2.2 2 0 0 2 2 2 1 WD domain, G-beta repeat Cytochrom_D1 PF02239.16 KSA01083.1 - 0.0003 19.4 1.7 1.9 6.9 0.0 4.3 5 0 0 5 5 5 2 Cytochrome D1 heme domain RAB3GAP2_N PF14655.6 KSA01083.1 - 0.014 14.7 0.0 3.2 6.9 0.0 3.5 4 0 0 4 4 4 0 Rab3 GTPase-activating protein regulatory subunit N-terminus PD40 PF07676.12 KSA01083.1 - 0.56 10.2 5.3 6.8 6.8 0.1 3.7 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat MPP6 PF10175.9 KSA01084.1 - 6.5e-17 62.3 18.3 9.1e-17 61.8 18.3 1.2 1 0 0 1 1 1 1 M-phase phosphoprotein 6 ABC_tran_Xtn PF12848.7 KSA01084.1 - 8.2 6.5 11.1 0.5 10.4 0.5 2.5 2 1 1 3 3 3 0 ABC transporter UPF0029 PF01205.19 KSA01085.1 - 8.7e-14 51.7 0.0 1.7e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.22 KSA01085.1 - 1.5e-08 34.9 1.6 1.5e-08 34.9 1.6 2.1 2 1 0 2 2 2 1 RWD domain Dict-STAT-coil PF09267.10 KSA01085.1 - 0.0047 17.3 1.8 0.27 11.6 0.1 2.4 2 0 0 2 2 2 2 Dictyostelium STAT, coiled coil Glyco_trans_1_2 PF13524.6 KSA01085.1 - 0.079 13.4 0.0 5.8 7.4 0.1 2.3 2 0 0 2 2 2 0 Glycosyl transferases group 1 TPR_1 PF00515.28 KSA01086.1 - 2.3e-14 52.5 0.4 0.00012 21.7 0.0 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KSA01086.1 - 1.2e-12 46.9 0.0 0.0067 16.5 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 KSA01086.1 - 6.2e-06 25.8 0.1 0.00066 19.3 0.1 2.6 2 0 0 2 2 2 1 TPR repeat RPAP3_C PF13877.6 KSA01086.1 - 9.2e-06 26.1 0.0 2.2e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 TPR_14 PF13428.6 KSA01086.1 - 5.9e-05 23.5 0.0 1.2 10.1 0.0 3.3 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 KSA01086.1 - 0.00051 20.2 0.8 0.0058 16.9 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 KSA01086.1 - 0.0021 18.1 0.1 5.4 7.5 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 KSA01086.1 - 0.0051 17.4 0.0 25 5.8 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 KSA01086.1 - 0.0063 17.0 0.0 0.029 14.9 0.0 2.0 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KSA01086.1 - 0.01 16.5 0.0 0.018 15.7 0.0 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_9 PF13371.6 KSA01086.1 - 0.12 12.5 0.0 1.2 9.4 0.0 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat Peptidase_S8 PF00082.22 KSA01087.1 - 3e-27 95.7 8.4 1.4e-26 93.4 8.4 1.9 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KSA01087.1 - 0.0025 18.5 0.0 0.0076 16.9 0.0 1.8 1 0 0 1 1 1 1 Peptidase inhibitor I9 ACC_central PF08326.12 KSA01088.1 - 6.8e-260 864.3 0.6 8.6e-260 864.0 0.6 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 KSA01088.1 - 5.9e-180 599.1 0.0 1.5e-179 597.8 0.0 1.7 2 0 0 2 2 2 1 Carboxyl transferase domain RhoGAP PF00620.27 KSA01088.1 - 0.12 12.2 1.4 0.6 9.9 0.1 2.6 2 0 0 2 2 2 0 RhoGAP domain Metallothio_Cad PF07846.11 KSA01088.1 - 0.26 11.4 0.1 0.48 10.6 0.1 1.4 1 0 0 1 1 1 0 Metallothionein family CPSase_L_D2 PF02786.17 KSA01089.1 - 1.7e-52 178.0 0.0 3.1e-52 177.2 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KSA01089.1 - 1.2e-28 99.9 0.1 2.7e-28 98.7 0.1 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KSA01089.1 - 2.6e-22 79.0 0.0 3.9e-21 75.2 0.0 2.5 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 KSA01089.1 - 9.5e-11 41.4 0.0 2.7e-10 39.9 0.0 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_3 PF02655.14 KSA01089.1 - 8.8e-05 22.6 0.1 0.00068 19.7 0.0 2.5 2 1 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KSA01089.1 - 0.0013 18.3 0.0 0.0035 16.9 0.0 1.6 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus GxGYxYP_N PF16216.5 KSA01089.1 - 0.013 15.6 0.0 0.03 14.5 0.0 1.5 1 0 0 1 1 1 0 GxGYxY sequence motif in domain of unknown function N-terminal ATPgrasp_Ter PF15632.6 KSA01089.1 - 0.021 14.5 0.0 0.047 13.4 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.22 KSA01089.1 - 0.094 12.3 0.1 0.32 10.6 0.1 1.8 1 1 0 1 1 1 0 ATP-grasp domain Tim17 PF02466.19 KSA01090.1 - 1.4e-26 93.0 3.3 1.9e-26 92.6 3.3 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Dus PF01207.17 KSA01091.1 - 2.9e-25 89.0 0.1 4.1e-24 85.2 0.0 1.8 1 1 1 2 2 2 2 Dihydrouridine synthase (Dus) SWIRM PF04433.17 KSA01092.1 - 2.3e-12 47.1 0.0 2.2e-11 43.9 0.0 2.3 2 0 0 2 2 2 1 SWIRM domain DUF2564 PF10819.8 KSA01093.1 - 1.3 9.5 5.9 20 5.6 5.9 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2564) Mis12 PF05859.12 KSA01095.1 - 4.8e-49 165.9 2.9 9.3e-49 164.9 2.9 1.5 1 0 0 1 1 1 1 Mis12 protein DUF3907 PF13047.6 KSA01095.1 - 0.015 15.3 3.4 0.15 12.0 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3907) DUF3198 PF11433.8 KSA01096.1 - 0.028 14.3 0.0 0.083 12.8 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3198) RPA43_OB PF17875.1 KSA01097.1 - 5.5e-24 85.2 0.2 5.5e-24 85.2 0.2 2.7 2 1 0 2 2 2 1 RPA43 OB domain in RNA Pol I SHS2_Rpb7-N PF03876.17 KSA01097.1 - 1.2e-14 54.4 0.0 2e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 LIN37 PF15306.6 KSA01097.1 - 0.42 10.8 3.4 0.7 10.1 3.4 1.3 1 0 0 1 1 1 0 LIN37 CorA PF01544.18 KSA01098.1 - 0.00054 19.4 2.5 0.00054 19.4 2.5 2.0 1 1 0 2 2 2 2 CorA-like Mg2+ transporter protein vATP-synt_E PF01991.18 KSA01099.1 - 6.5e-61 205.2 18.0 7.6e-61 205.0 18.0 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit FliH PF02108.16 KSA01099.1 - 2.1e-05 24.6 1.5 0.00045 20.3 0.1 2.7 1 1 2 3 3 3 1 Flagellar assembly protein FliH Mito_carr PF00153.27 KSA01100.1 - 3.4e-37 126.3 1.8 2.5e-19 69.0 0.2 2.3 2 0 0 2 2 2 2 Mitochondrial carrier protein GCP_N_terminal PF17681.1 KSA01101.1 - 1.1e-38 133.6 3.2 2.1e-38 132.7 3.2 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 KSA01101.1 - 2.9e-28 99.2 9.4 2.9e-28 99.2 9.4 1.9 2 1 0 2 2 2 1 Gamma tubulin complex component C-terminal ParB PF08775.10 KSA01101.1 - 0.13 12.7 3.1 0.42 11.1 0.0 3.1 3 0 0 3 3 3 0 ParB family Flo11 PF10182.9 KSA01102.1 - 4.3e-35 121.1 3.9 5.2e-35 120.8 3.9 1.1 1 0 0 1 1 1 1 Flo11 domain Peptidase_S10 PF00450.22 KSA01103.1 - 1.5e-134 449.5 0.4 2.3e-134 449.0 0.4 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.11 KSA01103.1 - 6.5e-40 136.6 1.7 1.1e-39 135.8 1.7 1.4 1 0 0 1 1 1 1 Carboxypeptidase Y pro-peptide Pkinase PF00069.25 KSA01104.1 - 8.3e-39 133.5 0.0 1e-38 133.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KSA01104.1 - 1.7e-17 63.6 0.0 2e-17 63.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.20 KSA01104.1 - 0.00037 20.1 0.3 0.00055 19.6 0.3 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 KSA01104.1 - 0.00095 19.2 0.4 0.0046 16.9 0.2 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KSA01104.1 - 0.011 14.5 0.0 0.018 13.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase SHMT PF00464.19 KSA01105.1 - 2.4e-204 678.4 0.0 2.8e-204 678.2 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 KSA01105.1 - 2e-05 24.0 0.0 8.8e-05 21.8 0.0 2.0 2 1 0 2 2 2 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KSA01105.1 - 0.078 12.3 0.0 0.21 10.8 0.0 1.6 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Med16 PF11635.8 KSA01106.1 - 1.9e-233 776.7 14.8 2.4e-233 776.4 14.8 1.0 1 0 0 1 1 1 1 Mediator complex subunit 16 IF2_N PF04760.15 KSA01106.1 - 0.027 14.3 1.0 0.14 12.0 0.1 2.6 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region DUF3938 PF13074.6 KSA01106.1 - 0.089 13.0 0.0 1.5 9.2 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3938) HSM3_C PF18794.1 KSA01107.1 - 1.3e-20 73.7 3.4 2.4e-20 72.9 0.2 2.4 2 0 0 2 2 2 1 DNA mismatch repair protein HSM3, C terminal domain Sec7 PF01369.20 KSA01108.1 - 1.1e-20 74.1 3.2 1.1e-20 74.1 3.2 2.9 3 0 0 3 3 3 1 Sec7 domain PH_9 PF15410.6 KSA01108.1 - 0.0034 17.7 1.0 0.0034 17.7 1.0 2.7 4 0 0 4 4 4 1 Pleckstrin homology domain Proteasome PF00227.26 KSA01109.1 - 8.7e-44 149.3 0.0 1.1e-43 149.0 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Cmc1 PF08583.10 KSA01110.1 - 4.9e-19 68.1 7.5 4.9e-19 68.1 7.5 1.4 2 0 0 2 2 2 1 Cytochrome c oxidase biogenesis protein Cmc1 like Takusan PF04822.13 KSA01110.1 - 0.0058 16.5 3.3 0.0094 15.8 3.3 1.6 1 1 0 1 1 1 1 Takusan CHCH PF06747.13 KSA01110.1 - 0.0087 16.2 4.0 0.13 12.4 0.5 2.5 2 0 0 2 2 2 2 CHCH domain DUF3338 PF11819.8 KSA01110.1 - 0.021 14.8 4.4 0.021 14.8 4.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3338) NDUF_B7 PF05676.13 KSA01110.1 - 0.034 13.9 2.1 0.054 13.2 2.1 1.4 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) DUF5427 PF10310.9 KSA01111.1 - 1e-109 367.6 18.2 1.4e-109 367.2 18.2 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5427) NARP1 PF12569.8 KSA01111.1 - 4.1 6.2 14.0 5.1 5.9 5.9 2.1 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 DUF1687 PF07955.11 KSA01112.1 - 2.1e-12 47.6 1.2 4.6e-12 46.5 1.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) CN_hydrolase PF00795.22 KSA01113.1 - 6.8e-43 146.9 0.0 8e-43 146.7 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DUF4921 PF16268.5 KSA01113.1 - 0.093 11.5 0.1 0.2 10.4 0.1 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4921) BCDHK_Adom3 PF10436.9 KSA01115.1 - 3.3e-66 222.1 0.1 9.5e-66 220.6 0.1 1.7 1 1 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KSA01115.1 - 4.5e-12 46.5 0.0 9.9e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3966 PF13110.6 KSA01115.1 - 0.02 14.8 0.2 0.04 13.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3966) Nop PF01798.18 KSA01115.1 - 0.045 13.2 0.4 0.087 12.3 0.4 1.4 1 0 0 1 1 1 0 snoRNA binding domain, fibrillarin Peroxin-13_N PF04088.13 KSA01116.1 - 1.3e-51 174.7 0.4 2e-51 174.1 0.4 1.2 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.17 KSA01116.1 - 1.8e-07 30.7 0.0 3.7e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KSA01116.1 - 2.8e-07 30.0 0.0 5.1e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KSA01116.1 - 1.5e-06 28.0 0.0 2.5e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 KSA01116.1 - 0.0096 16.2 0.2 0.031 14.5 0.0 2.0 2 0 0 2 2 2 1 Bacterial SH3 domain Pex2_Pex12 PF04757.14 KSA01116.1 - 0.055 13.0 0.0 0.14 11.7 0.0 1.6 1 1 0 1 1 1 0 Pex2 / Pex12 amino terminal region RcsF PF16358.5 KSA01117.1 - 0.00036 20.5 0.4 0.0038 17.3 0.1 2.1 1 1 1 2 2 2 2 RcsF lipoprotein KinB_sensor PF16767.5 KSA01117.1 - 0.019 15.4 0.9 0.28 11.6 0.2 2.5 1 1 2 3 3 3 0 Sensor domain of alginate biosynthesis sensor protein KinB MT0933_antitox PF14013.6 KSA01117.1 - 0.059 13.7 21.1 1.8 8.9 12.3 3.0 1 1 1 2 2 2 0 MT0933-like antitoxin protein DUF1378 PF07125.11 KSA01117.1 - 0.063 13.5 4.6 1.3 9.2 0.2 3.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1378) Flagellin_IN PF07196.13 KSA01117.1 - 0.19 11.9 1.3 9.8 6.5 0.1 2.6 1 1 1 2 2 2 0 Flagellin hook IN motif UPF0061 PF02696.14 KSA01118.1 - 0.019 13.8 0.0 0.021 13.6 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized ACR, YdiU/UPF0061 family GDA1_CD39 PF01150.17 KSA01119.1 - 9.1e-121 403.5 0.0 1.3e-120 403.0 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family NAD_kinase PF01513.21 KSA01120.1 - 1.4e-79 267.3 0.0 1.9e-79 266.9 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 KSA01120.1 - 0.003 17.2 0.0 0.0087 15.7 0.0 1.7 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Pox_A31 PF05771.11 KSA01120.1 - 0.067 13.2 0.3 0.48 10.4 0.1 2.2 2 0 0 2 2 2 0 Poxvirus A31 protein DEAD PF00270.29 KSA01121.1 - 2e-46 157.9 0.0 5.3e-46 156.6 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KSA01121.1 - 1e-30 106.3 0.0 2.5e-30 105.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KSA01121.1 - 0.0035 17.4 0.0 0.0071 16.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 KSA01121.1 - 0.075 12.4 0.0 0.26 10.6 0.0 1.8 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Gly_transf_sug PF04488.15 KSA01122.1 - 3.8e-15 56.3 0.2 7.8e-15 55.3 0.2 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 KSA01122.1 - 0.057 12.7 0.3 0.5 9.6 0.0 2.0 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain Isochorismatase PF00857.20 KSA01123.1 - 4e-23 82.5 0.4 1.6e-22 80.5 0.4 1.8 1 1 0 1 1 1 1 Isochorismatase family Isy1 PF06246.12 KSA01124.1 - 1.4e-71 241.1 13.1 1.7e-71 240.8 13.1 1.1 1 0 0 1 1 1 1 Isy1-like splicing family Spike_torovirin PF17072.5 KSA01124.1 - 0.12 9.5 0.0 0.16 9.1 0.0 1.0 1 0 0 1 1 1 0 Torovirinae spike glycoprotein Orthoreo_P17 PF07272.11 KSA01124.1 - 0.16 12.0 0.0 0.32 11.0 0.0 1.4 1 0 0 1 1 1 0 Orthoreovirus P17 protein Swi6_N PF18530.1 KSA01124.1 - 0.34 11.1 4.7 1.5 9.0 0.2 2.7 1 1 0 2 2 2 0 Swi6 N-terminal domain NUC153 PF08159.12 KSA01125.1 - 5.8e-15 54.8 1.2 1.4e-14 53.6 1.2 1.7 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.32 KSA01125.1 - 5.1e-05 24.0 0.4 0.34 11.9 0.0 4.1 4 0 0 4 4 4 1 WD domain, G-beta repeat DUF932 PF06067.11 KSA01125.1 - 0.035 13.9 5.7 0.067 12.9 5.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF932) ANAPC4_WD40 PF12894.7 KSA01125.1 - 0.035 14.4 0.0 0.14 12.4 0.0 2.2 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Herpes_UL17 PF04559.12 KSA01125.1 - 0.14 11.0 7.5 0.19 10.5 7.5 1.2 1 0 0 1 1 1 0 Herpesvirus UL17 protein Caskin-tail PF16632.5 KSA01126.1 - 0.17 12.3 0.7 0.44 11.0 0.7 1.7 1 0 0 1 1 1 0 C-terminal region of Caskin CENP-B_dimeris PF09026.10 KSA01127.1 - 1.3 9.4 12.0 2.5 8.5 4.9 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Lyase_1 PF00206.20 KSA01128.1 - 2.3e-100 336.0 0.0 4.4e-100 335.1 0.0 1.4 2 0 0 2 2 2 1 Lyase ASL_C2 PF14698.6 KSA01128.1 - 1.1e-21 77.3 0.0 2.5e-21 76.2 0.0 1.6 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal tRNA-synt_2 PF00152.20 KSA01129.1 - 7e-92 307.9 0.0 1.1e-91 307.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KSA01129.1 - 2.4e-12 46.6 0.2 4.8e-12 45.7 0.2 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Ins134_P3_kin PF05770.11 KSA01129.1 - 0.11 12.0 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain ProRS-C_1 PF09180.11 KSA01130.1 - 1.6e-25 89.1 0.9 3.7e-25 87.9 0.9 1.7 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.25 KSA01130.1 - 7e-19 68.5 0.0 1.6e-18 67.3 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KSA01130.1 - 1e-18 67.2 0.0 3e-18 65.8 0.0 1.9 1 0 0 1 1 1 1 Anticodon binding domain tRNA_edit PF04073.15 KSA01130.1 - 3.5e-08 33.6 0.5 6.3e-08 32.7 0.5 1.3 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain PHP PF02811.19 KSA01131.1 - 5.1e-15 56.2 0.7 9.3e-15 55.3 0.3 1.6 2 0 0 2 2 2 1 PHP domain Glyco_hydro_101 PF12905.7 KSA01131.1 - 0.03 13.7 0.0 0.057 12.8 0.0 1.4 1 0 0 1 1 1 0 Endo-alpha-N-acetylgalactosaminidase tRNA-synt_2 PF00152.20 KSA01132.1 - 4.2e-77 259.3 0.1 5.8e-77 258.9 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KSA01132.1 - 5.8e-06 26.2 0.0 1.1e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain YabP PF07873.11 KSA01132.1 - 0.052 13.3 0.0 3 7.7 0.0 2.8 3 0 0 3 3 3 0 YabP family zf-Tim10_DDP PF02953.15 KSA01133.1 - 7.1e-21 73.6 5.6 9.5e-21 73.2 5.6 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Phasin_2 PF09361.10 KSA01133.1 - 0.011 15.9 0.0 0.13 12.6 0.0 1.9 1 1 1 2 2 2 0 Phasin protein Hormone_recep PF00104.30 KSA01133.1 - 0.032 13.8 2.3 0.033 13.7 2.3 1.1 1 0 0 1 1 1 0 Ligand-binding domain of nuclear hormone receptor Tam41_Mmp37 PF09139.11 KSA01133.1 - 0.06 12.8 0.6 0.059 12.8 0.6 1.0 1 0 0 1 1 1 0 Phosphatidate cytidylyltransferase, mitochondrial Bromodomain PF00439.25 KSA01134.1 - 3.4e-19 68.7 1.3 1.9e-17 63.1 1.0 2.5 2 0 0 2 2 2 2 Bromodomain Suc_Fer-like PF06999.12 KSA01135.1 - 5.1e-50 170.1 0.0 5.9e-50 169.9 0.0 1.0 1 0 0 1 1 1 1 Sucrase/ferredoxin-like SNF2_N PF00176.23 KSA01136.1 - 2e-66 224.1 0.0 4.4e-66 223.0 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KSA01136.1 - 5.4e-20 71.8 1.0 2.7e-19 69.5 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KSA01136.1 - 2.3e-07 31.0 0.0 2.3e-07 31.0 0.0 3.5 3 1 1 4 4 4 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KSA01137.1 - 8.4e-42 142.9 0.4 2e-41 141.7 0.4 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KSA01137.1 - 2.4e-23 82.6 1.5 7.4e-23 81.0 0.6 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KSA01137.1 - 3.4e-11 43.4 0.1 3.4e-11 43.4 0.1 2.2 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.14 KSA01137.1 - 0.023 14.7 0.0 0.052 13.5 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_22 PF13401.6 KSA01137.1 - 0.096 13.0 1.7 1.4 9.2 0.6 3.1 2 1 0 2 2 2 0 AAA domain UvrD-helicase PF00580.21 KSA01137.1 - 0.19 11.2 7.9 0.013 15.0 1.5 2.1 2 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain NAM-associated PF14303.6 KSA01137.1 - 0.31 11.7 17.2 0.59 10.8 17.2 1.5 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain SprA-related PF12118.8 KSA01137.1 - 8.3 5.4 26.4 0.36 9.9 20.7 1.6 2 0 0 2 2 2 0 SprA-related family Ribosomal_S19 PF00203.21 KSA01138.1 - 3.3e-25 87.8 0.0 4.1e-25 87.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 PP2C PF00481.21 KSA01139.1 - 4e-36 125.0 0.2 1.5e-21 77.2 0.0 3.4 2 1 0 3 3 3 3 Protein phosphatase 2C PP2C_2 PF13672.6 KSA01139.1 - 0.00072 19.3 0.0 0.0013 18.4 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KSA01139.1 - 0.0046 16.9 0.0 0.054 13.4 0.0 2.3 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) LMBR1 PF04791.16 KSA01140.1 - 4.9e-68 230.3 37.1 4.9e-68 230.3 37.1 1.4 2 0 0 2 2 2 1 LMBR1-like membrane protein ADH_N PF08240.12 KSA01141.1 - 0.00028 20.7 0.0 0.0005 19.9 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DUF764 PF05561.11 KSA01141.1 - 0.008 16.0 0.7 0.027 14.3 0.7 1.9 1 0 0 1 1 1 1 Borrelia burgdorferi protein of unknown function (DUF764) DUF2722 PF10846.8 KSA01142.1 - 4.7e-159 530.3 29.7 5.3e-159 530.2 29.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) CSRNP_N PF16019.5 KSA01142.1 - 0.31 10.9 4.5 0.21 11.5 0.3 2.2 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus RSB_motif PF16294.5 KSA01142.1 - 1.7 8.9 6.2 0.25 11.6 0.2 2.4 2 1 1 3 3 3 0 RNSP1-SAP18 binding (RSB) motif CENP-B_dimeris PF09026.10 KSA01142.1 - 4.1 7.8 16.7 7.9 6.9 16.7 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RXT2_N PF08595.11 KSA01142.1 - 6.4 6.8 15.7 3.4 7.7 10.6 2.5 2 0 0 2 2 2 0 RXT2-like, N-terminal SHQ1 PF04925.15 KSA01143.1 - 2.4e-69 232.4 1.3 3.9e-69 231.7 1.3 1.3 1 0 0 1 1 1 1 SHQ1 protein PIH1_CS PF18201.1 KSA01143.1 - 0.006 17.0 0.0 0.023 15.1 0.0 2.0 2 0 0 2 2 2 1 PIH1 CS-like domain Diphthamide_syn PF01866.17 KSA01144.1 - 7.1e-118 393.5 0.1 8.8e-118 393.2 0.1 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein DUF5331 PF17265.2 KSA01144.1 - 0.12 12.2 0.1 0.25 11.1 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5331) COG6 PF06419.11 KSA01145.1 - 7.5e-165 549.7 30.5 1.2e-164 549.0 30.5 1.2 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 RFX5_N PF18326.1 KSA01145.1 - 0.023 14.5 0.9 0.82 9.5 0.1 2.9 2 0 0 2 2 2 0 RFX5 N-terminal domain Laminin_II PF06009.12 KSA01145.1 - 0.025 14.6 1.2 0.025 14.6 1.2 3.3 4 1 1 5 5 5 0 Laminin Domain II DASH_Dad3 PF08656.10 KSA01145.1 - 0.048 13.7 0.5 0.048 13.7 0.5 3.9 4 1 0 4 4 4 0 DASH complex subunit Dad3 FAS_I_H PF18314.1 KSA01145.1 - 0.26 10.9 3.3 4.6 6.8 0.1 3.0 2 1 1 3 3 3 0 Fatty acid synthase type I helical domain HTH_26 PF13443.6 KSA01145.1 - 0.86 10.1 3.5 1.8 9.0 0.2 2.8 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain Iso_dh PF00180.20 KSA01147.1 - 1.9e-73 247.6 0.0 2.2e-73 247.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase VHS PF00790.19 KSA01148.1 - 4.8e-05 23.2 0.7 0.0013 18.6 0.0 2.8 3 0 0 3 3 3 1 VHS domain CTD_bind PF04818.13 KSA01148.1 - 0.018 15.8 0.1 0.11 13.4 0.0 2.3 2 0 0 2 2 2 0 RNA polymerase II-binding domain. UBN_AB PF14075.6 KSA01148.1 - 0.13 12.0 0.6 0.64 9.7 0.0 2.1 2 0 0 2 2 2 0 Ubinuclein conserved middle domain COX7C PF02935.16 KSA01149.1 - 1.6e-20 73.1 5.7 1.9e-20 72.9 5.7 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc ABC_trans_CmpB PF06541.11 KSA01149.1 - 0.033 14.4 0.1 0.037 14.3 0.1 1.1 1 0 0 1 1 1 0 Putative ABC-transporter type IV NDUF_B12 PF08122.12 KSA01150.1 - 0.04 14.0 0.4 0.054 13.5 0.4 1.4 1 1 0 1 1 1 0 NADH-ubiquinone oxidoreductase B12 subunit family Sec1 PF00995.23 KSA01151.1 - 2e-68 232.1 22.0 2.4e-68 231.8 22.0 1.1 1 0 0 1 1 1 1 Sec1 family PepSY PF03413.19 KSA01151.1 - 0.0019 18.7 0.0 0.0047 17.5 0.0 1.6 1 0 0 1 1 1 1 Peptidase propeptide and YPEB domain Complex1_51K PF01512.17 KSA01151.1 - 0.11 12.4 0.0 1 9.2 0.0 2.1 2 0 0 2 2 2 0 Respiratory-chain NADH dehydrogenase 51 Kd subunit 4HBT_3 PF13622.6 KSA01152.1 - 9.1e-34 117.8 0.0 1.2e-33 117.4 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 KSA01152.1 - 8.5e-12 45.1 0.1 3.8e-09 36.5 0.1 2.9 2 1 0 2 2 2 2 Acyl-CoA thioesterase 4HBT_3 PF13622.6 KSA01153.1 - 1.3e-35 123.8 0.0 1.6e-35 123.6 0.0 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 KSA01153.1 - 6.8e-11 42.1 0.2 1e-08 35.1 0.1 2.7 2 1 0 2 2 2 2 Acyl-CoA thioesterase 4HBT_3 PF13622.6 KSA01154.1 - 1.9e-41 142.9 0.0 2.5e-41 142.6 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 KSA01154.1 - 2.3e-17 63.1 0.1 2.8e-12 46.6 0.1 3.0 2 1 0 2 2 2 2 Acyl-CoA thioesterase 4HBT_3 PF13622.6 KSA01155.1 - 3.2e-27 96.4 0.0 3.7e-27 96.2 0.0 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 KSA01155.1 - 1.2e-10 41.4 1.1 1.4e-07 31.4 0.4 3.6 3 1 1 4 4 4 2 Acyl-CoA thioesterase DUF2555 PF10742.9 KSA01155.1 - 0.11 12.3 0.2 0.32 10.9 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2555) NPCC PF08058.11 KSA01156.1 - 5e-35 120.4 0.0 1.1e-34 119.3 0.0 1.6 1 0 0 1 1 1 1 Nuclear pore complex component MRP-L20 PF12824.7 KSA01156.1 - 0.034 14.3 0.2 0.089 12.9 0.2 1.7 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit L20 HATPase_c_3 PF13589.6 KSA01157.1 - 5.3e-13 49.0 0.0 1e-12 48.1 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KSA01157.1 - 2.5e-06 28.0 0.0 5.8e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.11 KSA01157.1 - 1.3e-05 25.0 0.4 5.2e-05 23.0 0.1 2.2 2 1 0 2 2 2 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 KSA01157.1 - 0.0089 15.7 0.1 0.12 12.0 0.0 2.8 2 1 1 3 3 3 1 DNA mismatch repair protein, C-terminal domain Mito_carr PF00153.27 KSA01159.1 - 1.5e-54 181.9 3.1 1.5e-18 66.5 0.1 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KSA01159.1 - 0.031 13.4 0.1 0.061 12.5 0.1 1.7 2 0 0 2 2 2 0 Gammaproteobacterial serine protease DIOX_N PF14226.6 KSA01160.1 - 5.2e-32 111.1 0.0 9.2e-32 110.3 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KSA01160.1 - 1.5e-14 54.3 0.0 2.5e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily E1-E2_ATPase PF00122.20 KSA01161.1 - 6e-18 65.0 0.0 1.4e-17 63.8 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KSA01161.1 - 7.8e-17 62.3 0.0 5.7e-10 39.8 0.0 3.0 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KSA01161.1 - 9.1e-07 28.9 0.0 3.8e-05 23.7 0.0 2.5 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KSA01161.1 - 0.00069 19.4 0.4 0.0029 17.4 0.4 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 KSA01161.1 - 0.095 12.2 0.0 0.29 10.6 0.0 1.7 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase CDT1_C PF16679.5 KSA01162.1 - 3.4e-12 46.6 1.0 5.6e-12 45.9 0.1 1.8 2 0 0 2 2 2 1 DNA replication factor Cdt1 C-terminal domain CDT1 PF08839.11 KSA01162.1 - 0.0019 18.5 1.4 0.0034 17.7 1.4 1.7 1 1 0 1 1 1 1 DNA replication factor CDT1 like Carn_acyltransf PF00755.20 KSA01164.1 - 3.7e-143 478.3 0.0 4.9e-143 477.8 0.0 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase zf-C2H2 PF00096.26 KSA01165.1 - 2.1e-13 49.9 17.3 3.8e-06 27.1 2.0 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KSA01165.1 - 5.2e-13 48.8 12.8 4.5e-09 36.3 2.1 4.9 4 1 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KSA01165.1 - 6.3e-11 42.2 14.1 0.00015 22.3 1.6 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KSA01165.1 - 8.9e-08 32.0 12.1 5.8e-06 26.2 1.1 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KSA01165.1 - 3.8e-06 27.0 12.9 0.012 15.9 0.4 4.0 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KSA01165.1 - 0.0091 16.4 9.1 0.55 10.7 0.5 3.8 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2HE PF16278.5 KSA01165.1 - 0.037 14.5 0.9 0.037 14.5 0.9 3.1 2 1 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf_UBZ PF18439.1 KSA01165.1 - 0.13 11.9 4.0 2.5 7.8 0.1 3.1 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_12 PF11331.8 KSA01165.1 - 0.28 11.0 1.4 0.59 10.0 1.4 1.6 1 0 0 1 1 1 0 Probable zinc-ribbon domain zf-C2H2_11 PF16622.5 KSA01165.1 - 0.72 9.7 7.9 1.9 8.4 0.1 3.8 4 0 0 4 4 4 0 zinc-finger C2H2-type Zf_RING PF16744.5 KSA01165.1 - 0.89 9.7 7.2 15 5.8 0.2 3.3 1 1 2 3 3 3 0 KIAA1045 RING finger zf_ZIC PF18366.1 KSA01165.1 - 1.1 9.4 6.2 4.4 7.5 0.1 3.1 2 1 1 3 3 3 0 Zic proteins zinc finger domain XPA_N PF01286.18 KSA01165.1 - 1.1 9.4 4.4 8.7 6.5 0.4 3.3 3 0 0 3 3 3 0 XPA protein N-terminal C1_4 PF07975.12 KSA01165.1 - 2.3 8.5 7.9 4.2 7.7 5.1 2.6 2 1 1 3 3 2 0 TFIIH C1-like domain zf-H2C2_5 PF13909.6 KSA01165.1 - 7.9 6.3 13.4 5.7 6.8 5.6 3.9 3 1 0 3 3 3 0 C2H2-type zinc-finger domain Ribonuclease_3 PF00636.26 KSA01166.1 - 2.7e-20 72.9 0.0 1.7e-19 70.4 0.0 2.4 1 0 0 1 1 1 1 Ribonuclease III domain dsrm PF00035.26 KSA01166.1 - 1.3e-18 67.4 1.1 7e-08 33.1 0.0 2.7 2 0 0 2 2 2 2 Double-stranded RNA binding motif Ribonucleas_3_3 PF14622.6 KSA01166.1 - 1.3e-16 60.9 0.7 3.2e-16 59.7 0.7 1.8 1 0 0 1 1 1 1 Ribonuclease-III-like RNase_3_N PF18497.1 KSA01166.1 - 1.4e-07 31.7 1.1 5e-07 29.9 1.1 2.0 1 0 0 1 1 1 1 Ribonuclease III N-terminal domain Ribosomal_L10 PF00466.20 KSA01167.1 - 0.0006 19.9 0.0 0.0012 19.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L10 Methyltransf_4 PF02390.17 KSA01168.1 - 5.5e-62 208.3 0.2 8.1e-62 207.7 0.2 1.2 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 KSA01168.1 - 3.1e-05 23.6 0.0 0.00017 21.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 KSA01168.1 - 0.00015 22.4 0.0 0.00046 20.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KSA01168.1 - 0.00015 22.4 0.5 0.00032 21.4 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KSA01168.1 - 0.00053 19.8 0.1 0.0015 18.3 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KSA01168.1 - 0.018 14.3 0.0 0.034 13.4 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 KSA01168.1 - 0.038 14.6 0.0 0.22 12.2 0.0 2.3 2 1 0 2 2 2 0 Methyltransferase domain FliD_N PF02465.18 KSA01168.1 - 0.13 13.0 0.6 0.3 11.8 0.6 1.6 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus Methyltransf_32 PF13679.6 KSA01168.1 - 0.15 12.1 0.4 0.52 10.3 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain DUF4629 PF15442.6 KSA01168.1 - 0.74 10.0 9.1 3 8.1 8.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4629) Reticulon PF02453.17 KSA01169.1 - 3.6e-37 127.7 4.9 4.6e-37 127.4 4.9 1.1 1 0 0 1 1 1 1 Reticulon DUF4736 PF15883.5 KSA01169.1 - 0.033 13.9 1.4 0.43 10.3 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4736) RhoGEF PF00621.20 KSA01170.1 - 1.4e-19 71.0 17.6 4.3e-19 69.5 7.9 3.6 2 1 1 3 3 3 2 RhoGEF domain VPS11_C PF12451.8 KSA01171.1 - 2e-13 50.3 0.0 6.3e-13 48.7 0.0 1.9 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-C3H2C3 PF17122.5 KSA01171.1 - 1.1e-08 34.9 4.9 1.1e-08 34.9 4.9 2.1 2 0 0 2 2 2 1 Zinc-finger zf-RING_5 PF14634.6 KSA01171.1 - 0.012 15.6 7.7 0.028 14.4 7.7 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-rbx1 PF12678.7 KSA01171.1 - 0.014 15.7 4.9 0.036 14.3 4.9 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KSA01171.1 - 0.036 14.1 5.4 0.11 12.5 5.4 1.9 1 0 0 1 1 1 0 RING-type zinc-finger zf-ANAPC11 PF12861.7 KSA01171.1 - 0.047 13.8 1.9 0.094 12.8 1.9 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-HC5HC2H_2 PF13832.6 KSA01171.1 - 0.28 11.4 4.1 0.76 10.0 4.1 1.7 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-C3HC4_2 PF13923.6 KSA01171.1 - 1.9 8.4 11.6 0.051 13.4 4.1 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KSA01171.1 - 2.9 8.3 13.5 0.18 12.2 7.8 2.0 2 0 0 2 2 2 0 Ring finger domain FANCL_C PF11793.8 KSA01171.1 - 3.7 7.8 7.1 0.88 9.8 2.6 2.3 2 1 0 2 2 2 0 FANCL C-terminal domain zf-HC5HC2H PF13771.6 KSA01171.1 - 6.7 7.0 10.4 0.51 10.6 4.9 1.9 2 0 0 2 2 2 0 PHD-like zinc-binding domain Vps39_1 PF10366.9 KSA01171.1 - 8.6 6.7 14.8 0.32 11.3 5.3 3.3 3 0 0 3 3 2 0 Vacuolar sorting protein 39 domain 1 DUF916 PF06030.12 KSA01173.1 - 0.014 15.4 2.5 0.014 15.4 2.5 3.3 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF916) Acetyltransf_1 PF00583.25 KSA01174.1 - 2.6e-13 50.2 0.0 3e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KSA01174.1 - 8e-09 35.5 0.0 9.5e-09 35.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KSA01174.1 - 5.2e-07 30.0 0.0 6.9e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KSA01174.1 - 0.011 15.8 0.0 0.014 15.5 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain ADH_zinc_N_2 PF13602.6 KSA01175.1 - 2.1e-15 57.9 0.0 4e-15 57.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KSA01175.1 - 6e-13 48.9 0.0 3.6e-11 43.2 0.0 2.5 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KSA01175.1 - 0.00016 21.6 0.0 0.00032 20.5 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Semialdhyde_dh PF01118.24 KSA01175.1 - 0.066 13.6 0.0 0.11 13.0 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Sugar_tr PF00083.24 KSA01176.1 - 7.1e-111 371.2 21.8 8.8e-111 370.9 21.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KSA01176.1 - 7.4e-16 58.0 37.0 5.9e-12 45.2 14.7 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KSA01176.1 - 0.001 17.4 0.8 0.001 17.4 0.8 2.3 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family OppC_N PF12911.7 KSA01176.1 - 7.7 6.6 12.4 0.088 12.8 0.7 3.2 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C Pkinase PF00069.25 KSA01177.1 - 2.1e-34 119.1 0.4 6.9e-22 78.1 0.3 3.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KSA01177.1 - 2.5e-17 63.0 0.0 1.2e-13 50.9 0.0 2.7 3 0 0 3 3 3 2 Protein tyrosine kinase Kdo PF06293.14 KSA01177.1 - 0.0095 15.3 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KSA01177.1 - 0.081 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 KSA01178.1 - 2.1e-66 224.0 0.0 3e-66 223.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KSA01178.1 - 4.6e-47 160.5 0.0 7.3e-47 159.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.6 KSA01178.1 - 2.1e-37 127.5 0.0 4.7e-37 126.3 0.0 1.6 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_2 PF07647.17 KSA01178.1 - 1.8e-09 37.6 0.2 8.5e-09 35.4 0.2 2.2 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KSA01178.1 - 1.4e-08 35.1 0.9 3.9e-08 33.6 0.2 2.2 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.6 KSA01178.1 - 7.3e-07 28.8 0.0 8.2e-05 22.1 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 KSA01178.1 - 0.026 13.3 0.0 0.064 12.0 0.0 1.6 1 0 0 1 1 1 0 Fungal protein kinase Metallophos PF00149.28 KSA01179.1 - 3e-17 63.8 0.0 1.3e-16 61.8 0.0 2.1 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase CASP_C PF08172.12 KSA01181.1 - 6.5e-76 255.0 3.8 6.5e-76 255.0 3.8 3.9 3 2 1 4 4 4 1 CASP C terminal DUF2935 PF11155.8 KSA01181.1 - 8e-09 35.9 2.6 0.007 16.7 0.1 5.1 3 1 1 4 4 4 2 Domain of unknown function (DUF2935) Mto2_bdg PF12808.7 KSA01181.1 - 0.00061 20.0 1.9 0.00061 20.0 1.9 6.3 8 2 1 9 9 9 1 Micro-tubular organiser Mto1 C-term Mto2-binding region TPR_MLP1_2 PF07926.12 KSA01181.1 - 0.00078 19.5 70.3 0.066 13.3 10.7 7.0 4 2 3 7 7 7 4 TPR/MLP1/MLP2-like protein DUF1192 PF06698.11 KSA01181.1 - 0.0095 16.0 12.4 0.71 10.0 0.3 4.9 4 0 0 4 4 4 1 Protein of unknown function (DUF1192) DUF4407 PF14362.6 KSA01181.1 - 9.8 5.4 43.7 0.67 9.3 5.2 4.5 1 1 3 4 4 4 0 Domain of unknown function (DUF4407) Ribosomal_L21e PF01157.18 KSA01182.1 - 1.3e-47 159.8 3.3 1.3e-47 159.8 3.3 1.8 2 0 0 2 2 2 1 Ribosomal protein L21e Surface_Ag_2 PF01617.17 KSA01182.1 - 0.04 13.4 0.2 0.046 13.1 0.2 1.2 1 0 0 1 1 1 0 Surface antigen HIRAN PF08797.11 KSA01182.1 - 0.047 13.6 0.5 0.14 12.1 0.2 1.9 2 1 0 2 2 2 0 HIRAN domain S4 PF01479.25 KSA01183.1 - 1.7e-10 40.5 0.3 1.7e-10 40.5 0.3 2.4 3 0 0 3 3 3 1 S4 domain Ribosomal_S4 PF00163.19 KSA01183.1 - 0.0002 22.2 0.3 0.00043 21.1 0.2 1.7 1 1 1 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain Diphthami_syn_2 PF01902.17 KSA01184.1 - 2.7e-41 141.5 0.1 6e-41 140.3 0.1 1.6 1 1 0 1 1 1 1 Diphthamide synthase Ribonuc_L-PSP PF01042.21 KSA01184.1 - 5.2e-17 62.0 0.0 8.1e-09 35.5 0.0 2.5 2 0 0 2 2 2 2 Endoribonuclease L-PSP HLH PF00010.26 KSA01185.1 - 2.3e-08 33.8 3.3 3.3e-08 33.4 1.7 1.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain GCR PF02155.15 KSA01185.1 - 0.052 12.6 0.2 0.061 12.4 0.2 1.2 1 0 0 1 1 1 0 Glucocorticoid receptor DUF3322 PF11795.8 KSA01185.1 - 0.079 13.0 0.1 0.096 12.7 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) LicD PF04991.13 KSA01187.1 - 8.1e-28 98.1 10.0 6.6e-27 95.1 2.4 4.3 4 1 1 5 5 5 2 LicD family CN_hydrolase PF00795.22 KSA01188.1 - 1.4e-19 70.5 0.1 5.7e-17 61.9 0.0 2.8 3 0 0 3 3 3 2 Carbon-nitrogen hydrolase LicD PF04991.13 KSA01189.1 - 5.9e-31 108.4 7.5 2e-26 93.6 3.4 4.1 3 1 0 4 4 4 2 LicD family COX6A PF02046.15 KSA01190.1 - 6.3e-43 145.8 2.1 7.2e-43 145.6 2.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa WD40 PF00400.32 KSA01191.1 - 2e-14 53.7 2.9 0.0046 17.8 0.2 6.8 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KSA01191.1 - 0.00028 21.1 0.6 4.2 7.7 0.0 4.7 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KSA01191.1 - 7.9 6.3 8.7 2.7 7.8 1.5 3.4 3 2 2 5 5 5 0 Eukaryotic translation initiation factor eIF2A Ribosomal_S26e PF01283.19 KSA01192.1 - 3.3e-52 175.5 10.3 3.8e-52 175.3 10.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e COX5B PF01215.19 KSA01194.1 - 4.3e-54 181.7 0.1 5e-54 181.5 0.1 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-CHCC PF10276.9 KSA01194.1 - 0.76 9.9 4.8 1.2 9.3 4.8 1.3 1 0 0 1 1 1 0 Zinc-finger domain 2-Hacid_dh_C PF02826.19 KSA01195.1 - 3.9e-40 137.1 0.0 5.6e-40 136.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KSA01195.1 - 8.1e-14 51.4 0.0 1e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain IlvN PF07991.12 KSA01195.1 - 0.00055 19.6 0.0 0.00092 18.8 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain F420_oxidored PF03807.17 KSA01195.1 - 0.0031 18.1 0.0 0.0082 16.7 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 KSA01195.1 - 0.0035 17.5 0.1 0.012 15.8 0.0 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_7 PF13241.6 KSA01195.1 - 0.0086 16.5 0.0 0.017 15.5 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Rossmann-like PF10727.9 KSA01195.1 - 0.052 13.4 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Rossmann-like domain ApbA PF02558.16 KSA01195.1 - 0.064 12.9 0.1 0.15 11.7 0.1 1.7 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GFO_IDH_MocA PF01408.22 KSA01195.1 - 0.19 12.5 0.5 0.76 10.6 0.1 2.2 2 1 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold SH3_1 PF00018.28 KSA01196.1 - 2.7e-34 116.5 9.5 1.4e-12 47.0 0.2 4.3 4 0 0 4 4 4 3 SH3 domain SHD1 PF03983.12 KSA01196.1 - 4.5e-32 109.7 0.0 8.9e-32 108.7 0.0 1.5 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_9 PF14604.6 KSA01196.1 - 4.6e-31 106.4 8.8 1.7e-11 43.8 0.4 4.2 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.17 KSA01196.1 - 3.4e-23 81.1 0.4 8.8e-07 28.5 0.0 4.6 4 0 0 4 4 4 3 Variant SH3 domain SAM_4 PF18017.1 KSA01196.1 - 0.00067 19.6 0.0 0.0012 18.7 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Abhydro_lipase PF04083.16 KSA01197.1 - 2.5e-18 65.4 0.0 4.9e-18 64.5 0.0 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 KSA01197.1 - 1.5e-05 24.8 0.7 4.6e-05 23.2 0.7 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KSA01197.1 - 0.00078 18.8 0.1 0.0053 16.1 0.1 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 KSA01197.1 - 0.004 16.1 0.0 0.0069 15.3 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase enzyme LCAT PF02450.15 KSA01197.1 - 0.069 12.3 1.9 0.12 11.5 0.1 2.2 3 0 0 3 3 3 0 Lecithin:cholesterol acyltransferase Mito_carr PF00153.27 KSA01198.1 - 6.5e-64 211.9 3.2 6.5e-23 80.5 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein 2-Hacid_dh_C PF02826.19 KSA01199.1 - 3.4e-50 169.8 0.0 9.4e-50 168.4 0.0 1.7 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KSA01199.1 - 6.5e-13 48.5 0.0 8.3e-13 48.1 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain F420_oxidored PF03807.17 KSA01199.1 - 0.015 15.9 0.0 0.035 14.7 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Rpn9_C PF18261.1 KSA01199.1 - 0.027 14.1 2.0 0.095 12.3 0.2 2.4 2 0 0 2 2 2 0 Rpn9 C-terminal helix Peptidase_M28 PF04389.17 KSA01200.1 - 2.8e-38 131.6 0.2 3.8e-38 131.2 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KSA01200.1 - 1.3e-08 34.8 0.0 3e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 KSA01200.1 - 0.00069 19.4 0.0 0.0012 18.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 DUF4082 PF13313.6 KSA01200.1 - 0.055 13.5 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4082) DnaJ PF00226.31 KSA01201.1 - 1.3e-19 70.0 6.3 1.3e-19 70.0 6.3 2.1 2 0 0 2 2 2 1 DnaJ domain TPR_8 PF13181.6 KSA01201.1 - 0.0027 17.8 7.9 0.0081 16.3 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 KSA01201.1 - 0.039 13.8 0.2 0.039 13.8 0.2 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 KSA01201.1 - 0.039 14.1 7.6 0.99 9.7 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat RPA43_OB PF17875.1 KSA01201.1 - 0.13 12.9 2.9 0.3 11.7 2.9 1.6 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I DUF3371 PF11851.8 KSA01201.1 - 0.79 10.8 5.1 3 9.0 5.1 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3371) DUF2722 PF10846.8 KSA01201.1 - 1.3 7.8 17.8 0.36 9.7 14.9 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Pex14_N PF04695.13 KSA01201.1 - 4.8 7.8 17.0 0.81 10.3 11.6 2.3 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4834 PF16118.5 KSA01201.1 - 5.2 8.1 9.4 14 6.7 9.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) ANAPC_CDC26 PF10471.9 KSA01201.1 - 7.2 7.5 25.1 0.31 11.9 18.3 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 AAA PF00004.29 KSA01202.1 - 3.2e-43 147.3 0.0 6e-43 146.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KSA01202.1 - 1.2e-14 53.8 0.1 2.6e-14 52.7 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KSA01202.1 - 1.9e-07 31.2 0.0 5.7e-07 29.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KSA01202.1 - 9e-07 29.2 0.0 2.1e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Prot_ATP_ID_OB PF16450.5 KSA01202.1 - 9.8e-06 25.4 0.3 2.6e-05 24.1 0.3 1.8 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 KSA01202.1 - 1.3e-05 25.6 0.0 0.00022 21.7 0.0 2.6 2 1 0 3 3 2 1 AAA ATPase domain AAA_22 PF13401.6 KSA01202.1 - 2.3e-05 24.7 0.7 0.012 15.9 0.0 2.4 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 KSA01202.1 - 0.00018 21.3 0.0 0.00037 20.3 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KSA01202.1 - 0.00079 19.6 0.0 0.0016 18.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KSA01202.1 - 0.0011 19.5 0.1 0.02 15.4 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.6 KSA01202.1 - 0.0027 17.8 0.1 0.028 14.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KSA01202.1 - 0.0044 16.8 0.0 0.0089 15.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_17 PF13207.6 KSA01202.1 - 0.0087 16.5 0.1 0.45 11.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_13 PF13166.6 KSA01202.1 - 0.011 14.5 0.3 0.23 10.0 0.2 2.0 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.11 KSA01202.1 - 0.011 15.6 0.0 0.028 14.3 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.13 KSA01202.1 - 0.012 14.9 0.0 0.029 13.6 0.0 1.6 1 1 0 1 1 1 0 TIP49 P-loop domain AAA_28 PF13521.6 KSA01202.1 - 0.015 15.5 0.0 0.031 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KSA01202.1 - 0.016 14.6 0.0 0.035 13.5 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TsaE PF02367.17 KSA01202.1 - 0.018 15.1 0.0 0.036 14.1 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_11 PF13086.6 KSA01202.1 - 0.02 14.7 0.2 0.65 9.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KSA01202.1 - 0.024 15.0 0.0 0.045 14.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.6 KSA01202.1 - 0.025 14.1 0.0 0.064 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain TMF_TATA_bd PF12325.8 KSA01202.1 - 0.027 14.7 0.2 0.09 13.0 0.2 1.9 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DivIC PF04977.15 KSA01202.1 - 0.027 14.2 0.5 0.067 13.0 0.5 1.7 1 0 0 1 1 1 0 Septum formation initiator AAA_24 PF13479.6 KSA01202.1 - 0.034 13.8 0.0 0.089 12.5 0.0 1.7 2 0 0 2 2 1 0 AAA domain PhoH PF02562.16 KSA01202.1 - 0.035 13.6 0.0 0.14 11.6 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein Tropomyosin PF00261.20 KSA01202.1 - 0.042 13.2 2.7 0.064 12.6 0.9 1.9 2 0 0 2 2 2 0 Tropomyosin DUF5082 PF16888.5 KSA01202.1 - 0.045 14.0 1.2 0.1 12.9 1.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) APG6_N PF17675.1 KSA01202.1 - 0.047 14.2 1.9 0.095 13.2 1.9 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region HrpB7 PF09486.10 KSA01202.1 - 0.051 14.0 0.5 0.093 13.1 0.5 1.3 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) ATPase PF06745.13 KSA01202.1 - 0.054 12.8 0.1 0.16 11.3 0.0 1.8 2 0 0 2 2 2 0 KaiC Zeta_toxin PF06414.12 KSA01202.1 - 0.061 12.6 0.0 0.51 9.6 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin AAA_7 PF12775.7 KSA01202.1 - 0.061 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF2072 PF09845.9 KSA01202.1 - 0.065 13.5 0.5 0.14 12.4 0.5 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein DUF4763 PF15960.5 KSA01202.1 - 0.076 12.3 2.4 0.14 11.4 2.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) NACHT PF05729.12 KSA01202.1 - 0.082 12.8 0.0 0.22 11.4 0.0 1.7 2 0 0 2 2 1 0 NACHT domain Sigma54_activat PF00158.26 KSA01202.1 - 0.088 12.5 0.0 0.5 10.1 0.0 2.2 3 0 0 3 3 3 0 Sigma-54 interaction domain Spc24 PF08286.11 KSA01202.1 - 0.11 12.7 0.2 0.31 11.3 0.2 1.8 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 ATG16 PF08614.11 KSA01202.1 - 0.13 12.5 4.1 0.21 11.8 4.1 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) EzrA PF06160.12 KSA01202.1 - 2.2 6.4 5.8 1.3 7.1 2.5 1.9 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA MIF4G PF02854.19 KSA01203.1 - 6.4e-40 137.1 1.9 1e-39 136.4 1.9 1.3 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.8 KSA01203.1 - 6.2e-21 74.4 0.5 6.2e-21 74.4 0.5 2.5 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 4G1 DUF3566 PF12089.8 KSA01204.1 - 0.067 13.6 1.3 0.11 12.9 1.3 1.2 1 0 0 1 1 1 0 Transmembrane domain of unknown function (DUF3566) AAA PF00004.29 KSA01205.1 - 3.1e-16 60.0 0.1 1.2e-15 58.1 0.1 2.0 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KSA01205.1 - 2.5e-12 46.8 0.2 1.4e-11 44.4 0.3 2.2 1 1 1 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KSA01205.1 - 9e-06 25.7 0.0 2.2e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KSA01205.1 - 3.2e-05 24.4 0.2 0.0028 18.1 0.0 2.6 1 1 1 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 KSA01205.1 - 0.00011 22.2 0.5 0.00068 19.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_assoc_2 PF16193.5 KSA01205.1 - 0.00013 22.2 0.0 0.00051 20.3 0.0 2.1 1 0 0 1 1 1 1 AAA C-terminal domain AAA_22 PF13401.6 KSA01205.1 - 0.00041 20.6 0.5 0.011 16.0 0.5 2.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KSA01205.1 - 0.00045 20.4 0.0 0.0032 17.6 0.0 2.6 1 1 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 KSA01205.1 - 0.00047 19.9 0.0 0.0074 16.0 0.0 2.3 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_18 PF13238.6 KSA01205.1 - 0.00059 20.4 0.0 0.0034 17.9 0.0 2.4 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 KSA01205.1 - 0.00064 19.6 0.0 0.0013 18.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 KSA01205.1 - 0.0015 18.3 0.0 0.0032 17.2 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.14 KSA01205.1 - 0.0016 18.6 0.0 0.0051 16.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_7 PF12775.7 KSA01205.1 - 0.0046 16.5 0.0 0.014 15.0 0.0 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_17 PF13207.6 KSA01205.1 - 0.014 15.8 0.0 0.063 13.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KSA01205.1 - 0.024 15.0 0.7 0.68 10.3 0.0 3.1 3 0 0 3 3 2 0 RNA helicase AAA_24 PF13479.6 KSA01205.1 - 0.035 13.8 0.0 0.12 12.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KSA01205.1 - 0.049 13.9 0.0 0.096 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain LIM_bind PF01803.16 KSA01206.1 - 1.8e-51 175.0 4.0 1.8e-51 175.0 4.0 2.8 3 0 0 3 3 3 1 LIM-domain binding protein KCNQC3-Ank-G_bd PF11956.8 KSA01206.1 - 0.13 12.6 0.1 0.3 11.4 0.1 1.6 1 0 0 1 1 1 0 Ankyrin-G binding motif of KCNQ2-3 PAPA-1 PF04795.12 KSA01207.1 - 1.3e-14 54.7 3.7 1.3e-14 54.7 3.7 5.2 2 2 1 3 3 3 1 PAPA-1-like conserved region Foamy_virus_ENV PF03408.14 KSA01209.1 - 0.00079 17.4 0.2 0.00094 17.2 0.2 1.0 1 0 0 1 1 1 1 Foamy virus envelope protein DarT PF14487.6 KSA01209.1 - 0.028 14.3 0.0 0.032 14.1 0.0 1.2 1 0 0 1 1 1 0 ssDNA thymidine ADP-ribosyltransferase, DarT Neugrin PF06413.11 KSA01210.1 - 4.2e-07 30.2 0.1 4.2e-07 30.2 0.1 1.4 2 0 0 2 2 2 1 Neugrin HTH_DeoR PF08220.12 KSA01210.1 - 0.025 14.3 0.0 0.054 13.2 0.0 1.6 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain VID27 PF08553.10 KSA01211.1 - 1.2e-159 531.2 3.1 1.6e-159 530.7 3.1 1.2 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain VID27_N PF17748.1 KSA01211.1 - 1.4e-54 184.5 0.8 3.4e-54 183.3 0.0 2.1 2 0 0 2 2 2 1 VID27 N-terminal region VID27_PH PF17747.1 KSA01211.1 - 5.2e-32 110.4 4.9 5.2e-32 110.4 4.9 2.1 2 0 0 2 2 2 1 VID27 PH-like domain RGS PF00615.19 KSA01213.1 - 2.2e-07 31.1 0.3 3.4e-07 30.5 0.3 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain Ribosomal_S15 PF00312.22 KSA01213.1 - 0.043 14.0 0.1 1.2 9.4 0.0 2.3 2 0 0 2 2 2 0 Ribosomal protein S15 Cytomega_gL PF01801.16 KSA01214.1 - 0.0045 16.4 0.1 0.0084 15.5 0.1 1.4 1 0 0 1 1 1 1 Cytomegalovirus glycoprotein L LPG_synthase_TM PF03706.13 KSA01214.1 - 0.77 9.2 12.0 1.3 8.5 12.0 1.4 1 0 0 1 1 1 0 Lysylphosphatidylglycerol synthase TM region bZIP_2 PF07716.15 KSA01215.1 - 1.8e-12 47.2 7.8 3.4e-12 46.3 7.8 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KSA01215.1 - 0.01 15.9 10.2 0.02 15.0 10.2 1.4 1 0 0 1 1 1 0 bZIP transcription factor TSC22 PF01166.18 KSA01215.1 - 0.14 12.5 2.8 0.35 11.2 2.5 1.9 1 1 0 1 1 1 0 TSC-22/dip/bun family YabA PF06156.13 KSA01215.1 - 0.48 11.1 5.0 1 10.0 5.0 1.5 1 0 0 1 1 1 0 Initiation control protein YabA DUF4988 PF16378.5 KSA01215.1 - 0.94 9.1 4.1 11 5.6 1.0 2.3 1 1 1 2 2 2 0 Domain of unknown function NAM-associated PF14303.6 KSA01215.1 - 3.8 8.2 16.1 0.083 13.6 8.9 2.0 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain CPSase_L_D2 PF02786.17 KSA01217.1 - 3.1e-81 271.9 0.3 6.6e-81 270.8 0.3 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 KSA01217.1 - 1.3e-64 217.6 0.0 2.2e-64 216.9 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 KSA01217.1 - 2.3e-39 134.3 0.0 4.9e-39 133.3 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KSA01217.1 - 1.5e-30 105.4 0.0 4.2e-30 104.0 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 KSA01217.1 - 2.8e-25 89.4 0.0 7.9e-25 87.9 0.0 1.7 2 0 0 2 2 2 1 HMGL-like Biotin_lipoyl PF00364.22 KSA01217.1 - 3.7e-18 65.1 4.8 3.7e-18 65.1 4.8 2.8 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 KSA01217.1 - 2.1e-08 33.9 1.1 0.0014 18.4 0.1 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 KSA01217.1 - 8.4e-06 25.5 0.0 1.8e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 KSA01217.1 - 0.00021 21.4 0.0 0.00055 20.0 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.6 KSA01217.1 - 0.0067 17.1 1.0 4.4 8.1 0.1 2.9 2 0 0 2 2 2 1 HlyD family secretion protein PYNP_C PF07831.13 KSA01217.1 - 0.0087 15.7 1.5 0.14 11.9 0.0 3.1 3 0 0 3 3 3 1 Pyrimidine nucleoside phosphorylase C-terminal domain DUF2118 PF09891.9 KSA01217.1 - 0.015 15.3 0.1 0.064 13.2 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2118) ATPgrasp_ST PF14397.6 KSA01217.1 - 0.024 13.9 0.0 0.074 12.3 0.0 1.8 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp GCV_H PF01597.19 KSA01217.1 - 0.046 13.6 2.6 0.19 11.6 0.7 2.6 1 1 1 2 2 2 0 Glycine cleavage H-protein HlyD_D23 PF16576.5 KSA01217.1 - 0.078 12.2 0.3 0.38 10.0 0.1 2.0 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion RnfC_N PF13375.6 KSA01217.1 - 0.51 10.3 4.5 0.72 9.9 1.3 2.9 2 1 0 2 2 2 0 RnfC Barrel sandwich hybrid domain DASH_Duo1 PF08651.10 KSA01218.1 - 1.7e-25 88.6 8.4 1.7e-25 88.6 8.4 2.0 2 0 0 2 2 2 1 DASH complex subunit Duo1 DUF4806 PF16064.5 KSA01218.1 - 0.36 11.2 3.5 1.3 9.4 0.3 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4806) DASH_Dad2 PF08654.10 KSA01218.1 - 0.37 11.2 12.2 1.2 9.5 12.2 1.8 1 1 0 1 1 1 0 DASH complex subunit Dad2 APG6_N PF17675.1 KSA01218.1 - 0.95 10.0 21.5 1.5 9.4 15.7 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region AAA_23 PF13476.6 KSA01218.1 - 1.8 9.0 17.3 2.6 8.5 17.3 1.3 1 0 0 1 1 1 0 AAA domain Mvb12 PF09452.10 KSA01218.1 - 1.9 9.0 6.4 10 6.6 1.5 2.2 1 1 0 2 2 2 0 ESCRT-I subunit Mvb12 Syntaxin-6_N PF09177.11 KSA01218.1 - 5.2 7.7 13.9 3.8 8.1 10.9 2.0 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Med31 PF05669.12 KSA01219.1 - 5.7e-39 132.0 5.1 6.8e-39 131.8 5.1 1.1 1 0 0 1 1 1 1 SOH1 Scs3p PF10261.9 KSA01220.1 - 4.6e-71 239.2 13.5 8e-71 238.4 13.5 1.4 1 1 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM He_PIG PF05345.12 KSA01221.1 - 4.2e-14 52.5 5.8 7.7e-08 32.4 1.5 4.6 4 0 0 4 4 4 2 Putative Ig domain SKG6 PF08693.10 KSA01221.1 - 4.3e-06 26.0 0.0 1.3e-05 24.5 0.0 1.9 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Mid2 PF04478.12 KSA01221.1 - 0.0012 18.7 0.0 0.0036 17.1 0.0 1.8 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor TMEM154 PF15102.6 KSA01221.1 - 0.0021 18.0 1.6 0.0033 17.3 0.0 2.2 2 0 0 2 2 2 1 TMEM154 protein family DUF4448 PF14610.6 KSA01221.1 - 0.0022 17.8 0.0 0.0047 16.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) MLANA PF14991.6 KSA01221.1 - 0.013 15.7 0.0 0.035 14.4 0.0 1.7 1 0 0 1 1 1 0 Protein melan-A Pox_A12 PF04651.13 KSA01221.1 - 1.6 8.8 15.4 0.065 13.3 8.9 2.0 2 0 0 2 2 2 0 Poxvirus A12 protein 4HBT PF03061.22 KSA01222.1 - 0.00022 21.5 0.2 0.98 9.8 0.0 3.1 2 1 0 2 2 2 2 Thioesterase superfamily Transket_pyr PF02779.24 KSA01223.1 - 4.2e-45 153.6 0.0 6.7e-45 152.9 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KSA01223.1 - 1.5e-39 134.7 0.1 2.6e-39 133.9 0.1 1.4 1 0 0 1 1 1 1 Transketolase, C-terminal domain Hairpins PF04877.12 KSA01223.1 - 2.2 7.8 4.2 5.2 6.6 0.4 2.4 1 1 1 2 2 2 0 HrpZ Acatn PF13000.7 KSA01224.1 - 3.1e-191 636.6 26.9 2.7e-126 422.3 15.2 2.6 1 1 1 2 2 2 2 Acetyl-coenzyme A transporter 1 Adeno_E3_14_5 PF04834.12 KSA01224.1 - 0.028 14.9 0.2 0.48 11.0 0.0 2.5 2 0 0 2 2 2 0 Early E3 14.5 kDa protein PQ-loop PF04193.14 KSA01225.1 - 4.4e-32 109.6 24.5 9.5e-19 66.9 3.9 3.5 4 0 0 4 4 4 2 PQ loop repeat GTP_EFTU_D3 PF03143.17 KSA01226.1 - 3.2e-26 91.8 0.1 8e-26 90.5 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KSA01226.1 - 5.2e-20 71.6 3.1 6.5e-20 71.3 1.9 1.8 2 1 0 2 2 2 1 Elongation factor Tu domain 2 ANAPC1 PF12859.7 KSA01227.1 - 2.9e-09 37.6 1.7 6.4e-09 36.5 1.7 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 1 Herpes_UL16 PF03044.14 KSA01227.1 - 0.14 11.4 0.1 1.2 8.3 0.0 1.9 1 1 1 2 2 2 0 Herpesvirus UL16/UL94 family PC_rep PF01851.22 KSA01228.1 - 0.00018 21.8 2.1 4.1 8.0 0.0 5.4 5 0 0 5 5 5 2 Proteasome/cyclosome repeat Malt_amylase_C PF16657.5 KSA01228.1 - 0.05 13.7 0.1 1.3 9.2 0.0 2.8 2 0 0 2 2 2 0 Maltogenic Amylase, C-terminal domain VirJ PF06057.11 KSA01228.1 - 0.055 13.3 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) PS_Dcarbxylase PF02666.15 KSA01229.1 - 7.8e-78 260.6 0.1 1.7e-74 249.7 0.1 2.2 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase Big_5 PF13205.6 KSA01229.1 - 0.0068 17.1 1.2 0.015 16.0 1.2 1.5 1 0 0 1 1 1 1 Bacterial Ig-like domain Mob1_phocein PF03637.17 KSA01230.1 - 2.5e-65 219.6 0.4 3.3e-65 219.2 0.4 1.2 1 0 0 1 1 1 1 Mob1/phocein family RNA_pol PF00940.19 KSA01231.1 - 1.2e-179 597.5 0.4 1.6e-179 597.1 0.4 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 KSA01231.1 - 9.7e-83 278.3 0.1 1.7e-82 277.5 0.1 1.4 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal DrrA_P4M PF14860.6 KSA01231.1 - 0.043 13.7 0.3 0.99 9.3 0.1 2.6 2 0 0 2 2 2 0 DrrA phosphatidylinositol 4-phosphate binding domain RPOL_N PF14700.6 KSA01232.1 - 1.7e-06 27.7 0.2 3e-06 26.9 0.2 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal PPR_2 PF13041.6 KSA01232.1 - 0.00035 20.7 0.6 9.6 6.5 0.0 4.4 4 0 0 4 4 4 2 PPR repeat family DUF4898 PF16239.5 KSA01232.1 - 0.0046 16.9 0.3 0.017 15.1 0.3 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4898) Ku_PK_bind PF08785.11 KSA01232.1 - 0.017 15.3 0.2 0.12 12.5 0.0 2.4 2 0 0 2 2 2 0 Ku C terminal domain like Snf7 PF03357.21 KSA01233.1 - 1.5e-43 148.4 21.7 1.5e-43 148.4 21.7 1.9 1 1 1 2 2 2 1 Snf7 DASH_Dad4 PF08650.10 KSA01233.1 - 0.062 13.3 2.6 0.37 10.8 0.7 2.5 2 0 0 2 2 2 0 DASH complex subunit Dad4 NuA4 PF09340.10 KSA01233.1 - 0.26 11.2 0.2 0.26 11.2 0.2 2.4 3 0 0 3 3 3 0 Histone acetyltransferase subunit NuA4 DUF2730 PF10805.8 KSA01233.1 - 0.62 10.2 6.7 0.27 11.3 2.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) CCDC53 PF10152.9 KSA01233.1 - 3.4 8.1 15.3 9.9 6.6 15.3 1.8 1 1 0 1 1 1 0 Subunit CCDC53 of WASH complex YppG PF14179.6 KSA01233.1 - 5.2 7.8 9.4 15 6.3 2.6 3.1 2 1 0 2 2 2 0 YppG-like protein SNARE PF05739.19 KSA01234.1 - 2.8e-13 49.6 0.3 5.9e-13 48.6 0.3 1.6 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 KSA01234.1 - 0.00074 19.2 0.5 0.00074 19.2 0.5 3.2 2 1 1 3 3 3 1 Syntaxin Syntaxin-5_N PF11416.8 KSA01234.1 - 0.0011 18.1 2.5 0.0028 16.8 0.8 2.4 2 0 0 2 2 2 1 Syntaxin-5 N-terminal, Sly1p-binding domain DUF16 PF01519.16 KSA01234.1 - 0.0017 18.8 0.4 0.0017 18.8 0.4 2.5 2 1 0 2 2 2 1 Protein of unknown function DUF16 MCPsignal PF00015.21 KSA01234.1 - 0.015 15.1 0.5 0.015 15.1 0.5 2.4 3 0 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Syntaxin-18_N PF10496.9 KSA01234.1 - 0.072 13.4 3.8 0.11 12.8 1.2 2.4 2 0 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus V-SNARE PF05008.15 KSA01234.1 - 2.7 8.4 6.4 1.5 9.2 0.1 3.3 3 1 1 4 4 4 0 Vesicle transport v-SNARE protein N-terminus Syntaxin_2 PF14523.6 KSA01234.1 - 3.5 8.0 20.4 11 6.5 0.9 3.4 3 0 0 3 3 3 0 Syntaxin-like protein Tubulin_C PF03953.17 KSA01235.1 - 2.1e-43 147.5 0.1 3.4e-43 146.8 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.25 KSA01235.1 - 1.7e-33 116.5 0.0 3.3e-33 115.6 0.0 1.5 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_3 PF14881.6 KSA01235.1 - 0.0046 16.7 0.0 0.0088 15.7 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 KSA01235.1 - 0.012 14.8 0.1 0.041 13.1 0.0 1.8 2 0 0 2 2 2 0 Tubulin like Complex1_LYR PF05347.15 KSA01236.1 - 2.4e-12 46.7 0.4 3.9e-12 46.0 0.4 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KSA01236.1 - 0.00013 22.6 0.6 0.00019 22.1 0.6 1.3 1 0 0 1 1 1 1 Complex1_LYR-like RIC1 PF07064.13 KSA01237.1 - 2.7e-31 108.9 2.6 5.3e-31 107.9 2.6 1.4 1 0 0 1 1 1 1 RIC1 FAD-oxidase_C PF02913.19 KSA01238.1 - 5e-51 173.7 0.0 7.5e-51 173.2 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KSA01238.1 - 4e-29 101.1 0.1 7.3e-29 100.3 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain FeoB_Cyto PF17910.1 KSA01239.1 - 0.00047 20.6 1.0 0.0013 19.2 0.1 2.2 1 1 1 2 2 2 1 FeoB cytosolic helical domain DUF948 PF06103.11 KSA01239.1 - 0.56 10.5 1.6 25 5.2 0.3 2.9 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF3659 PF12396.8 KSA01240.1 - 1.5e-16 60.0 26.1 1.6e-14 53.5 4.3 4.1 4 1 1 5 5 5 3 Protein of unknown function (DUF3659) Pes-10 PF07149.11 KSA01240.1 - 0.15 11.1 17.3 0.016 14.3 12.7 1.6 2 0 0 2 2 2 0 Pes-10 GTP_EFTU_D4 PF14578.6 KSA01240.1 - 0.94 9.4 6.2 2.3 8.2 0.0 3.9 3 2 2 5 5 5 0 Elongation factor Tu domain 4 CsbD PF05532.12 KSA01240.1 - 2.2 8.3 11.9 1.3 9.0 0.4 4.6 4 1 0 4 4 4 0 CsbD-like DNA_pol_phi PF04931.13 KSA01240.1 - 3 5.8 24.4 0.15 10.1 19.2 1.5 2 0 0 2 2 2 0 DNA polymerase phi SGT1 PF07093.11 KSA01240.1 - 5.8 5.2 12.9 9.5 4.5 12.9 1.3 1 0 0 1 1 1 0 SGT1 protein Epimerase PF01370.21 KSA01242.1 - 3.1e-11 43.2 0.0 5.8e-11 42.3 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KSA01242.1 - 3.2e-07 29.8 0.1 2.2e-05 23.8 0.1 2.1 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 KSA01242.1 - 9e-07 28.2 0.0 9.9e-07 28.0 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KSA01242.1 - 2.4e-05 24.3 0.1 5.7e-05 23.1 0.0 1.9 2 1 0 2 2 2 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KSA01242.1 - 0.00028 20.4 0.0 0.00044 19.8 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase F420_oxidored PF03807.17 KSA01242.1 - 0.00031 21.3 0.0 0.00056 20.4 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent adh_short PF00106.25 KSA01242.1 - 0.0015 18.1 0.0 0.0021 17.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Shikimate_DH PF01488.20 KSA01242.1 - 0.0018 18.4 0.0 0.0033 17.5 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NmrA PF05368.13 KSA01242.1 - 0.0036 16.9 0.0 0.0055 16.3 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 KSA01242.1 - 0.0073 16.6 0.0 0.012 15.8 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain ADH_zinc_N PF00107.26 KSA01242.1 - 0.051 13.5 0.0 0.084 12.9 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Semialdhyde_dh PF01118.24 KSA01242.1 - 0.15 12.5 0.1 0.4 11.1 0.0 1.5 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Ribosomal_S9 PF00380.19 KSA01243.1 - 8.1e-34 116.7 0.7 9.2e-34 116.6 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Ribosomal_L13e PF01294.18 KSA01244.1 - 3.1e-70 235.7 5.6 4.6e-70 235.1 5.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e Fmp27_SW PF10305.9 KSA01244.1 - 0.13 12.9 0.5 0.67 10.7 0.0 2.1 2 1 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain Ribosomal_60s PF00428.19 KSA01245.1 - 2.8e-25 88.7 12.8 3.4e-25 88.4 12.8 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF3245 PF11595.8 KSA01245.1 - 0.024 15.1 0.1 0.028 14.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) Cellulase PF00150.18 KSA01246.1 - 7.4e-17 61.7 7.9 3.9e-16 59.3 7.9 1.9 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Aminotran_5 PF00266.19 KSA01247.1 - 1.9e-14 53.4 0.0 2.6e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KSA01247.1 - 1.7e-07 30.8 0.0 2.2e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KSA01247.1 - 9.7e-06 24.3 0.0 1.5e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KSA01247.1 - 0.00055 19.3 0.0 0.0019 17.6 0.0 1.8 2 1 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family SepSecS PF05889.13 KSA01247.1 - 0.014 14.1 0.0 0.024 13.4 0.0 1.3 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS MDM31_MDM32 PF08118.11 KSA01248.1 - 3.8e-221 735.3 7.4 5.1e-221 734.9 7.4 1.1 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins INO80_Ies4 PF08193.11 KSA01249.1 - 3.6e-06 27.1 0.7 3.6e-06 27.1 0.7 2.5 1 1 1 2 2 2 2 INO80 complex subunit Ies4 Pol_alpha_B_N PF08418.10 KSA01249.1 - 3.1 7.7 11.1 0.66 9.9 7.7 1.5 1 1 1 2 2 2 0 DNA polymerase alpha subunit B N-terminal tRNA-synt_2b PF00587.25 KSA01250.1 - 9.8e-25 87.5 0.0 2.9e-24 86.0 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KSA01250.1 - 1.1e-16 60.7 0.1 1.9e-16 60.0 0.1 1.4 1 0 0 1 1 1 1 Anticodon binding domain CDC73_C PF05179.14 KSA01251.1 - 1.7e-52 177.2 3.2 3.6e-52 176.2 3.2 1.5 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal DUF2220 PF09983.9 KSA01251.1 - 0.036 13.4 0.0 0.12 11.8 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria C-term(DUF2220) APG17 PF04108.12 KSA01252.1 - 3.8e-79 266.6 11.2 4.6e-79 266.4 11.2 1.1 1 0 0 1 1 1 1 Autophagy protein Apg17 NLE PF08154.12 KSA01252.1 - 0.085 13.4 1.8 0.53 10.8 0.0 3.2 3 0 0 3 3 3 0 NLE (NUC135) domain DUF1687 PF07955.11 KSA01252.1 - 0.12 12.9 2.7 0.23 12.0 1.5 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1687) G-patch PF01585.23 KSA01253.1 - 1e-13 50.9 4.0 2e-13 50.0 4.0 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KSA01253.1 - 7.9e-06 25.9 0.8 2e-05 24.6 0.8 1.7 1 0 0 1 1 1 1 G-patch domain DnaB_C PF03796.15 KSA01253.1 - 0.0025 17.2 3.3 0.0044 16.4 3.3 1.3 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain Enkurin PF13864.6 KSA01253.1 - 6.6 7.2 10.9 7.3 7.1 2.1 2.8 1 1 1 2 2 2 0 Calmodulin-binding CHCH PF06747.13 KSA01255.1 - 5.6e-07 29.5 4.0 9.7e-07 28.8 4.0 1.4 1 0 0 1 1 1 1 CHCH domain GCK PF07802.11 KSA01255.1 - 0.0069 16.8 4.2 0.0069 16.8 4.2 2.1 2 1 0 2 2 2 1 GCK domain DUF4366 PF14283.6 KSA01255.1 - 4.5 7.3 14.3 0.49 10.4 7.6 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4366) Ras PF00071.22 KSA01256.1 - 2e-36 125.1 0.1 1.3e-24 86.6 0.0 2.3 2 1 0 2 2 2 2 Ras family Roc PF08477.13 KSA01256.1 - 1.2e-27 96.5 0.0 1.7e-16 60.5 0.0 2.3 1 1 1 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KSA01256.1 - 6e-10 38.8 0.7 2.5e-09 36.8 0.2 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KSA01256.1 - 4.8e-08 32.8 0.0 6.9e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KSA01256.1 - 0.0013 18.1 0.2 0.004 16.5 0.2 1.8 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region WD40 PF00400.32 KSA01257.1 - 1e-08 35.7 9.9 0.005 17.7 1.1 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat Nup160 PF11715.8 KSA01257.1 - 1.2e-06 27.5 0.4 3.9e-06 25.8 0.1 1.8 2 0 0 2 2 2 1 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KSA01257.1 - 0.00066 19.9 0.9 0.64 10.4 0.5 2.9 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 KSA01257.1 - 0.0083 16.6 1.0 0.037 14.5 0.0 2.6 3 0 0 3 3 3 1 PQQ-like domain NMT_C PF02799.15 KSA01258.1 - 2.4e-79 265.7 0.3 3.9e-79 265.0 0.3 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 KSA01258.1 - 6e-75 250.5 0.2 2.6e-74 248.4 0.0 1.9 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_1 PF00583.25 KSA01258.1 - 0.0049 17.1 0.0 0.0091 16.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family DUF5117 PF17148.4 KSA01259.1 - 0.0045 16.9 2.5 0.0045 16.9 2.5 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF5117) Pepsin-I3 PF06394.13 KSA01259.1 - 3.5 7.9 6.3 0.28 11.4 0.3 2.3 2 0 0 2 2 2 0 Pepsin inhibitor-3-like repeated domain F-box-like PF12937.7 KSA01260.1 - 8.2e-05 22.4 0.1 0.00018 21.3 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KSA01260.1 - 0.015 15.2 0.0 0.036 14.0 0.0 1.7 1 0 0 1 1 1 0 F-box domain MIT PF04212.18 KSA01260.1 - 0.14 12.3 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain eIF-3c_N PF05470.12 KSA01261.1 - 3.1e-150 501.4 23.7 8.8e-113 377.7 4.2 2.8 2 1 1 3 3 3 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 KSA01261.1 - 1.1e-10 41.9 0.1 6.7e-10 39.4 0.1 2.4 1 0 0 1 1 1 1 PCI domain Band_3_cyto PF07565.13 KSA01261.1 - 0.36 10.6 5.3 1.1 9.1 5.3 1.8 1 0 0 1 1 1 0 Band 3 cytoplasmic domain SUIM_assoc PF16619.5 KSA01261.1 - 1.1 9.4 12.1 3.2 7.9 12.1 1.7 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 DUF4355 PF14265.6 KSA01261.1 - 1.1 9.5 14.4 12 6.2 8.8 3.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) ATP_bind_3 PF01171.20 KSA01262.1 - 1.2e-18 67.5 0.0 3.7e-18 65.9 0.0 1.8 2 1 0 2 2 2 1 PP-loop family zn-ribbon_14 PF16503.5 KSA01262.1 - 3.3e-15 55.3 4.4 3.3e-15 55.3 4.4 3.8 4 0 0 4 4 4 1 Zinc-ribbon tRNA_Me_trans PF03054.16 KSA01262.1 - 0.03 13.1 0.0 0.081 11.7 0.0 1.7 1 1 0 1 1 1 0 tRNA methyl transferase Imm49 PF15575.6 KSA01262.1 - 0.15 11.8 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 49 adh_short PF00106.25 KSA01263.1 - 4.9e-48 163.2 0.0 6.6e-48 162.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KSA01263.1 - 4e-31 108.4 0.0 5.1e-31 108.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KSA01263.1 - 2e-11 44.1 0.0 2.7e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KSA01263.1 - 0.0028 17.1 0.0 0.0049 16.3 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.15 KSA01263.1 - 0.021 14.0 0.0 0.054 12.6 0.0 1.8 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 KSA01263.1 - 0.1 12.9 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain ThiF PF00899.21 KSA01263.1 - 0.11 11.8 0.3 0.18 11.2 0.3 1.2 1 0 0 1 1 1 0 ThiF family adh_short PF00106.25 KSA01264.1 - 1.1e-50 171.8 0.0 1.7e-50 171.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KSA01264.1 - 1.7e-34 119.4 0.0 2.2e-34 119.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KSA01264.1 - 2.2e-12 47.2 0.0 3.2e-12 46.7 0.0 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KSA01264.1 - 0.00039 19.9 0.0 0.00065 19.1 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.15 KSA01264.1 - 0.0029 16.8 0.1 0.0046 16.1 0.1 1.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 KSA01264.1 - 0.015 15.5 0.0 0.039 14.2 0.0 1.7 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Ribosomal_L18A PF01775.17 KSA01265.1 - 1.8e-54 183.0 1.0 1.8e-54 183.0 1.0 1.5 1 1 1 2 2 2 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A FA_hydroxylase PF04116.13 KSA01266.1 - 9.5e-25 87.5 19.7 9.5e-25 87.5 19.7 1.7 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily GATase PF00117.28 KSA01267.1 - 1.5e-46 158.6 0.0 2e-46 158.2 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.22 KSA01267.1 - 1.3e-45 154.3 0.0 2.3e-45 153.5 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain Peptidase_C26 PF07722.13 KSA01267.1 - 8.9e-05 22.3 0.2 0.0035 17.1 0.1 2.6 1 1 2 3 3 3 1 Peptidase C26 Bul1_N PF04425.12 KSA01268.1 - 1.4e-41 142.7 0.1 1.4e-41 142.7 0.1 1.6 2 0 0 2 2 2 1 Bul1 N terminus Bul1_C PF04426.12 KSA01268.1 - 3.8e-19 69.1 1.5 4.9e-09 36.0 1.3 2.5 1 1 1 2 2 2 2 Bul1 C terminus Phi-29_GP16_7 PF06720.11 KSA01268.1 - 0.004 17.0 0.5 0.01 15.7 0.0 1.9 2 0 0 2 2 2 1 Bacteriophage phi-29 early protein GP16.7 Bul1_N PF04425.12 KSA01269.1 - 9.3e-93 311.4 5.5 9.3e-93 311.4 5.5 1.9 1 1 1 2 2 2 1 Bul1 N terminus SUZ PF12752.7 KSA01269.1 - 2.4 9.0 0.0 2.4 9.0 0.0 3.5 3 1 0 3 3 3 0 SUZ domain DWNN PF08783.11 KSA01270.1 - 1.5e-25 89.3 0.0 3.4e-25 88.1 0.0 1.6 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.6 KSA01270.1 - 1.3e-07 31.2 7.0 2.8e-07 30.2 7.0 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 KSA01270.1 - 0.00093 19.2 3.3 0.00093 19.2 3.3 1.6 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_5 PF14787.6 KSA01270.1 - 0.011 15.5 0.2 0.03 14.0 0.2 1.8 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger Ku_C PF03730.14 KSA01270.1 - 0.02 15.6 0.5 0.02 15.6 0.5 2.2 2 1 1 3 3 3 0 Ku70/Ku80 C-terminal arm zf-CCHC_3 PF13917.6 KSA01270.1 - 0.032 14.2 0.2 0.085 12.8 0.2 1.7 1 0 0 1 1 1 0 Zinc knuckle DUF4144 PF13642.6 KSA01270.1 - 0.13 12.9 0.1 0.39 11.3 0.1 1.8 1 0 0 1 1 1 0 protein structure with unknown function zf-DNL PF05180.12 KSA01270.1 - 0.66 10.0 3.7 0.62 10.0 0.8 2.3 2 0 0 2 2 2 0 DNL zinc finger DUF4441 PF14536.6 KSA01270.1 - 1.6 8.9 6.4 1.7 8.9 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4441) Nup160 PF11715.8 KSA01271.1 - 1.8e-58 198.5 17.4 3.1e-58 197.7 17.4 1.3 1 0 0 1 1 1 1 Nucleoporin Nup120/160 T-box PF00907.22 KSA01271.1 - 0.28 11.4 2.6 0.21 11.9 0.3 2.0 2 0 0 2 2 2 0 T-box TAP42 PF04177.12 KSA01272.1 - 1.9e-76 257.2 8.2 2.2e-76 257.1 8.2 1.0 1 0 0 1 1 1 1 TAP42-like family DUF4999 PF16390.5 KSA01272.1 - 0.012 15.8 0.4 0.012 15.8 0.4 1.7 2 0 0 2 2 2 0 Domain of unknown function TFIIA_gamma_C PF02751.14 KSA01273.1 - 1.7e-24 85.7 2.9 2.7e-24 85.1 2.9 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.16 KSA01273.1 - 3.4e-24 84.6 0.7 4.9e-24 84.1 0.7 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain NUDIX PF00293.28 KSA01273.1 - 0.17 11.9 0.0 0.23 11.5 0.0 1.1 1 0 0 1 1 1 0 NUDIX domain DUF89 PF01937.19 KSA01274.1 - 1.8e-117 392.2 4.2 2.1e-117 392.0 4.2 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 PAP1 PF08601.10 KSA01276.1 - 5.3e-26 92.2 31.8 1.1e-25 91.1 31.8 1.6 1 1 0 1 1 1 1 Transcription factor PAP1 bZIP_1 PF00170.21 KSA01276.1 - 3.7e-10 39.8 7.8 8.7e-10 38.6 7.8 1.6 1 0 0 1 1 1 1 bZIP transcription factor CALCOCO1 PF07888.11 KSA01276.1 - 0.0018 17.2 3.9 0.0026 16.7 3.9 1.2 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like DUF4200 PF13863.6 KSA01276.1 - 0.0018 18.7 3.8 0.0036 17.7 3.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4200) bZIP_2 PF07716.15 KSA01276.1 - 0.0019 18.3 12.6 0.01 15.9 12.6 2.1 1 1 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KSA01276.1 - 0.0023 18.4 6.2 0.0045 17.5 6.2 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor Frigida PF07899.11 KSA01276.1 - 0.24 10.6 2.4 0.37 10.0 2.4 1.2 1 0 0 1 1 1 0 Frigida-like protein HR1 PF02185.16 KSA01276.1 - 2 8.6 6.0 3.8 7.7 0.0 2.4 1 1 1 2 2 2 0 Hr1 repeat NDUFA12 PF05071.16 KSA01277.1 - 8.4e-27 93.9 3.0 1.1e-26 93.5 3.0 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 DS PF01916.17 KSA01278.1 - 2.3e-130 434.0 0.0 2.7e-130 433.8 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Peptidase_M18 PF02127.15 KSA01279.1 - 5.1e-138 460.5 0.0 6e-138 460.2 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 KSA01279.1 - 0.027 13.5 0.0 0.63 9.0 0.0 2.1 1 1 1 2 2 2 0 M42 glutamyl aminopeptidase RRM_1 PF00076.22 KSA01280.1 - 0.0075 16.1 0.1 0.033 14.0 0.1 2.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-alpha PF00503.20 KSA01281.1 - 3.9e-108 361.8 4.7 5.2e-108 361.4 4.7 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KSA01281.1 - 3.5e-15 55.9 0.1 1.3e-09 37.7 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KSA01281.1 - 0.00044 19.7 0.4 0.21 10.9 0.0 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 KSA01281.1 - 0.028 14.7 0.2 1.5 9.1 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase FtsK_SpoIIIE PF01580.18 KSA01281.1 - 0.082 12.2 0.0 2.6 7.3 0.1 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_29 PF13555.6 KSA01281.1 - 0.11 12.3 0.2 0.26 11.1 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain C8 PF08742.11 KSA01282.1 - 0.037 14.4 2.6 0.081 13.4 2.6 1.5 1 0 0 1 1 1 0 C8 domain Pkinase PF00069.25 KSA01283.1 - 1.4e-73 247.5 0.0 1.8e-73 247.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KSA01283.1 - 4e-35 121.4 0.0 6.1e-35 120.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KSA01283.1 - 5.3e-05 22.7 0.0 0.0024 17.2 0.0 2.2 1 1 1 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KSA01283.1 - 0.00011 21.3 1.6 0.0021 17.0 1.6 2.6 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KSA01283.1 - 0.023 14.6 0.1 0.043 13.7 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KSA01283.1 - 0.051 12.3 1.8 0.69 8.6 0.1 2.4 2 0 0 2 2 2 0 Fungal protein kinase Seadorna_VP7 PF07387.11 KSA01283.1 - 0.093 11.8 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.22 KSA01283.1 - 0.34 10.5 3.6 0.25 10.9 0.2 2.1 2 0 0 2 2 2 0 RIO1 family SIS PF01380.22 KSA01284.1 - 8.9e-67 222.9 0.1 5.3e-36 123.4 0.1 2.2 2 0 0 2 2 2 2 SIS domain GATase_7 PF13537.6 KSA01284.1 - 3.1e-09 36.8 0.0 6.6e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KSA01284.1 - 4e-08 33.5 0.0 7e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain SIS_2 PF13580.6 KSA01284.1 - 0.12 12.4 0.0 0.35 10.9 0.0 1.9 2 0 0 2 2 2 0 SIS domain LXG PF04740.12 KSA01284.1 - 0.13 12.0 0.8 0.36 10.5 0.1 1.9 2 0 0 2 2 2 0 LXG domain of WXG superfamily DUF155 PF02582.14 KSA01285.1 - 1.3e-39 136.2 0.0 2.4e-39 135.3 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Candida_ALS_N PF11766.8 KSA01286.1 - 2.5e-65 220.2 7.0 2.5e-65 220.2 7.0 2.9 3 1 0 3 3 3 1 Cell-wall agglutinin N-terminal ligand-sugar binding Ammonium_transp PF00909.21 KSA01287.1 - 7e-103 344.4 21.7 8.3e-103 344.1 21.7 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF2632 PF10943.8 KSA01287.1 - 0.017 14.7 0.5 0.017 14.7 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2632) MtN3_slv PF03083.16 KSA01287.1 - 3.8 7.6 9.4 20 5.3 1.0 3.5 3 0 0 3 3 3 0 Sugar efflux transporter for intercellular exchange TPP_enzyme_N PF02776.18 KSA01288.1 - 4.3e-53 179.4 0.0 1.4e-52 177.8 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KSA01288.1 - 2.3e-50 170.4 2.0 1.2e-48 164.8 0.2 3.7 4 0 0 4 4 4 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KSA01288.1 - 3.1e-39 133.9 0.2 5.7e-39 133.0 0.2 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain CO_dh PF02552.16 KSA01288.1 - 0.05 13.4 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit P5CR_dimer PF14748.6 KSA01288.1 - 0.1 12.9 0.0 0.27 11.5 0.0 1.7 1 0 0 1 1 1 0 Pyrroline-5-carboxylate reductase dimerisation Ndufs5 PF10200.9 KSA01289.1 - 9.4e-05 22.6 0.2 0.00011 22.4 0.2 1.2 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa CHCH PF06747.13 KSA01289.1 - 0.02 15.0 2.6 0.11 12.6 2.7 2.1 1 1 2 3 3 3 0 CHCH domain COX6B PF02297.17 KSA01289.1 - 0.041 14.1 1.2 0.041 14.1 1.2 2.0 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb DUF3128 PF11326.8 KSA01289.1 - 0.11 12.8 3.5 3 8.3 3.5 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) UCR_hinge PF02320.16 KSA01289.1 - 0.17 12.1 2.8 2.5 8.4 0.4 2.2 1 1 1 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein Pet191_N PF10203.9 KSA01289.1 - 0.2 12.0 1.9 0.29 11.4 1.9 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 UPF0203 PF05254.12 KSA01289.1 - 0.22 11.8 3.7 0.36 11.1 3.7 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) Lactamase_B_6 PF16661.5 KSA01290.1 - 2.6e-71 239.1 0.0 5.2e-71 238.1 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 KSA01290.1 - 2.5e-33 115.7 0.0 2.5e-33 115.7 0.0 3.3 4 0 0 4 4 4 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 KSA01290.1 - 1.2e-12 48.0 0.1 6.2e-12 45.8 0.0 2.3 2 0 0 2 2 2 1 Beta-Casp domain Alg14 PF08660.11 KSA01290.1 - 0.083 12.8 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Oligosaccharide biosynthesis protein Alg14 like RMMBL PF07521.12 KSA01290.1 - 0.14 12.1 0.0 0.4 10.7 0.0 1.8 1 0 0 1 1 1 0 Zn-dependent metallo-hydrolase RNA specificity domain Transferase PF02458.15 KSA01291.1 - 2.2e-26 92.5 0.0 9.1e-26 90.5 0.0 1.8 1 1 0 1 1 1 1 Transferase family PhoLip_ATPase_C PF16212.5 KSA01292.1 - 2.3e-75 253.6 26.1 2.3e-75 253.6 26.1 2.5 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KSA01292.1 - 1e-16 60.4 2.3 1.5e-16 59.8 0.5 2.3 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 KSA01292.1 - 2.1e-12 46.9 0.0 6.2e-12 45.4 0.0 1.8 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KSA01292.1 - 1.3e-09 38.7 0.8 0.00018 21.9 0.1 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KSA01292.1 - 6.1e-09 35.7 0.0 1.9e-08 34.1 0.0 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KSA01292.1 - 0.0011 18.7 0.3 0.0011 18.7 0.3 2.8 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase NAC PF01849.18 KSA01293.1 - 1.3e-17 63.5 0.6 2.2e-17 62.8 0.1 1.7 2 0 0 2 2 2 1 NAC domain CSN5_C PF18323.1 KSA01293.1 - 0.013 16.4 4.6 0.032 15.1 4.6 1.6 1 0 0 1 1 1 0 Cop9 signalosome subunit 5 C-terminal domain Neur_chan_memb PF02932.16 KSA01293.1 - 0.044 13.8 1.1 0.052 13.6 1.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF5376 PF17346.2 KSA01293.1 - 0.056 13.8 0.4 0.11 12.9 0.4 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5376) DUF4407 PF14362.6 KSA01293.1 - 0.2 11.0 7.3 0.22 10.8 7.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AIF-MLS PF14962.6 KSA01293.1 - 1.5 8.7 8.5 2.1 8.3 8.5 1.2 1 0 0 1 1 1 0 Mitochondria Localisation Sequence XhlA PF10779.9 KSA01293.1 - 6.2 7.1 8.6 2.3 8.5 0.1 3.0 3 0 0 3 3 3 0 Haemolysin XhlA zinc_ribbon_10 PF10058.9 KSA01294.1 - 5e-22 77.4 0.1 8.4e-22 76.7 0.1 1.4 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein CCDC-167 PF15188.6 KSA01294.1 - 0.026 14.9 0.0 0.5 10.7 0.0 2.5 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 DUF2207 PF09972.9 KSA01294.1 - 0.029 13.1 2.2 0.023 13.5 0.6 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) LapA_dom PF06305.11 KSA01294.1 - 0.056 13.3 0.1 0.92 9.4 0.1 2.4 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain MIG-14_Wnt-bd PF06664.12 KSA01294.1 - 0.058 12.6 1.1 0.081 12.1 1.1 1.1 1 0 0 1 1 1 0 Wnt-binding factor required for Wnt secretion YlbD_coat PF14071.6 KSA01294.1 - 0.059 13.6 6.8 4.6 7.5 4.3 2.3 2 0 0 2 2 2 0 Putative coat protein DUF1610 PF07754.11 KSA01294.1 - 0.17 11.9 1.3 0.39 10.7 1.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1610) Zip PF02535.22 KSA01294.1 - 0.17 11.0 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DivIC PF04977.15 KSA01294.1 - 1.6 8.6 6.8 2.3 8.1 0.0 3.0 3 0 0 3 3 3 0 Septum formation initiator Rho_GDI PF02115.17 KSA01295.1 - 0.014 15.1 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 RHO protein GDP dissociation inhibitor Cdc13_OB2 PF18691.1 KSA01295.1 - 0.47 10.5 5.0 0.65 10.1 2.0 2.6 1 1 2 3 3 3 0 Cell division control protein 13, OB2 domain Pex24p PF06398.11 KSA01295.1 - 0.65 8.9 5.2 0.3 10.0 1.0 2.1 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin Ank_4 PF13637.6 KSA01296.1 - 2e-15 56.9 0.8 8e-06 26.3 0.0 3.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KSA01296.1 - 5.8e-10 39.6 0.7 0.00037 21.0 0.0 3.6 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KSA01296.1 - 5.6e-08 32.4 1.6 0.022 15.3 0.0 4.8 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 KSA01296.1 - 6.4e-06 26.4 0.1 2 9.0 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat KilA-N PF04383.13 KSA01296.1 - 6.8e-06 25.9 0.2 6.8e-06 25.9 0.2 3.6 3 2 0 3 3 3 1 KilA-N domain Ank_5 PF13857.6 KSA01296.1 - 9.2e-06 25.8 1.4 0.0034 17.6 0.0 3.8 3 1 0 3 3 3 1 Ankyrin repeats (many copies) Selenoprotein_S PF06936.11 KSA01296.1 - 0.38 10.5 3.9 0.94 9.3 3.9 1.6 1 0 0 1 1 1 0 Selenoprotein S (SelS) DUF3589 PF12141.8 KSA01297.1 - 9.9e-142 473.0 0.0 3.8e-140 467.8 0.0 2.0 1 1 0 1 1 1 1 Beta-mannosyltransferases MFS_1 PF07690.16 KSA01298.1 - 5.1e-40 137.5 31.9 5.1e-40 137.5 31.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KSA01298.1 - 4.5e-06 25.4 2.5 1e-05 24.2 2.5 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) FPN1 PF06963.12 KSA01298.1 - 0.002 16.7 1.2 0.002 16.7 1.2 2.1 2 0 0 2 2 2 1 Ferroportin1 (FPN1) Cas_GSU0054 PF09609.10 KSA01298.1 - 0.17 10.5 0.1 0.35 9.5 0.1 1.5 1 0 0 1 1 1 0 CRISPR-associated protein, GSU0054 family (Cas_GSU0054) Mod_r PF07200.13 KSA01299.1 - 1.2e-19 70.8 7.8 1.4e-19 70.6 7.8 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Sigma70_ner PF04546.13 KSA01299.1 - 0.024 14.6 0.7 0.032 14.1 0.7 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region SMC_hinge PF06470.13 KSA01299.1 - 0.1 12.9 0.1 0.18 12.1 0.1 1.4 1 0 0 1 1 1 0 SMC proteins Flexible Hinge Domain Pyr_redox_2 PF07992.14 KSA01301.1 - 6e-45 153.7 0.0 7.9e-45 153.3 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KSA01301.1 - 5.1e-09 36.6 0.7 1.6e-08 35.0 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KSA01301.1 - 0.006 15.9 0.3 0.46 9.7 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KSA01301.1 - 0.025 13.7 0.0 0.17 11.0 0.0 2.0 1 1 1 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) EF-hand_9 PF14658.6 KSA01301.1 - 0.056 13.8 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain DUF3112 PF11309.8 KSA01302.1 - 1.9e-97 325.0 9.1 3.8e-97 324.0 9.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3112) DUF3112 PF11309.8 KSA01303.1 - 1.4e-102 341.8 5.0 2.7e-102 340.8 5.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3112) CHD5 PF04420.14 KSA01303.1 - 0.012 15.4 1.9 0.04 13.8 0.6 2.3 2 0 0 2 2 2 0 CHD5-like protein DUF4500 PF14937.6 KSA01303.1 - 0.33 11.0 1.5 1.2 9.2 1.5 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4500) CytB6-F_Fe-S PF08802.10 KSA01303.1 - 0.49 10.5 2.2 1.4 9.0 2.2 1.8 1 0 0 1 1 1 0 Cytochrome B6-F complex Fe-S subunit DUF2663 PF10864.8 KSA01303.1 - 0.82 10.1 3.4 1.9 8.9 1.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2663) Ctf8 PF09696.10 KSA01304.1 - 8.9e-38 129.8 0.1 1e-37 129.6 0.1 1.1 1 0 0 1 1 1 1 Ctf8 Y_phosphatase3 PF13350.6 KSA01305.1 - 8.4e-60 202.6 0.0 1.4e-59 201.9 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Hydrolase_4 PF12146.8 KSA01305.1 - 1.9e-05 24.1 0.0 5.1e-05 22.7 0.0 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KSA01305.1 - 0.00065 19.4 0.1 0.0049 16.6 0.1 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold PTPlike_phytase PF14566.6 KSA01305.1 - 0.0048 17.0 0.0 0.013 15.6 0.0 1.7 1 0 0 1 1 1 1 Inositol hexakisphosphate Abhydrolase_6 PF12697.7 KSA01305.1 - 0.0079 16.8 0.0 0.011 16.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Y_phosphatase PF00102.27 KSA01305.1 - 0.016 14.8 0.0 0.031 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 KSA01305.1 - 0.073 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family EAP30 PF04157.16 KSA01306.1 - 3e-53 180.5 0.0 3.4e-53 180.4 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family PseudoU_synth_1 PF01416.20 KSA01307.1 - 2.5e-33 114.7 0.0 2.3e-30 105.3 0.0 2.5 2 0 0 2 2 2 2 tRNA pseudouridine synthase DEAD PF00270.29 KSA01308.1 - 7.6e-42 143.0 0.2 3.1e-41 141.1 0.1 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KSA01308.1 - 4.4e-26 91.4 0.1 8.1e-24 84.1 0.0 3.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KSA01308.1 - 1.4e-17 63.6 0.2 2.7e-17 62.7 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) UvrD-helicase PF00580.21 KSA01308.1 - 0.0066 16.0 6.4 0.12 11.9 0.0 2.5 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain Pyocin_S PF06958.12 KSA01308.1 - 0.049 14.2 0.0 0.11 13.1 0.0 1.5 1 0 0 1 1 1 0 S-type Pyocin E1_FCCH PF16190.5 KSA01308.1 - 0.057 13.6 0.4 0.22 11.7 0.4 2.0 1 1 0 2 2 2 0 Ubiquitin-activating enzyme E1 FCCH domain AAA_11 PF13086.6 KSA01308.1 - 0.12 12.1 4.7 0.39 10.5 4.7 1.9 1 0 0 1 1 1 0 AAA domain DUF4629 PF15442.6 KSA01308.1 - 4.7 7.4 20.2 11 6.3 20.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4629) ThiF PF00899.21 KSA01309.1 - 9.6e-22 77.5 0.0 1.3e-21 77.1 0.0 1.2 1 1 0 1 1 1 1 ThiF family E1_4HB PF16191.5 KSA01309.1 - 1.2e-07 31.8 0.1 0.28 11.4 0.1 3.8 3 0 0 3 3 3 3 Ubiquitin-activating enzyme E1 four-helix bundle tRNA_NucTran2_2 PF13735.6 KSA01309.1 - 0.046 13.7 0.5 0.29 11.1 0.1 2.2 2 0 0 2 2 2 0 tRNA nucleotidyltransferase domain 2 putative Terpene_synth_C PF03936.16 KSA01309.1 - 0.07 12.5 0.7 3.8 6.8 0.0 2.7 3 0 0 3 3 3 0 Terpene synthase family, metal binding domain SPX PF03105.19 KSA01310.1 - 5.5e-48 164.8 10.4 8.4e-48 164.2 10.4 1.3 1 0 0 1 1 1 1 SPX domain zf-RING_2 PF13639.6 KSA01310.1 - 4.8e-08 33.2 9.6 1.3e-07 31.9 9.6 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KSA01310.1 - 5.3e-08 32.6 8.1 1e-07 31.7 8.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KSA01310.1 - 6.9e-08 32.5 9.8 6.9e-08 32.5 9.8 1.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KSA01310.1 - 3.8e-07 29.9 6.8 9e-07 28.7 6.8 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KSA01310.1 - 7.6e-07 29.0 5.3 7.6e-07 29.0 5.3 2.4 2 1 1 3 3 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KSA01310.1 - 9.6e-07 28.6 10.6 9.6e-07 28.6 10.6 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KSA01310.1 - 7.2e-06 25.9 11.5 7e-05 22.7 12.0 2.2 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KSA01310.1 - 2.3e-05 24.1 10.6 5.1e-05 23.0 10.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TerY_C PF15616.6 KSA01310.1 - 0.00098 19.2 0.4 0.00098 19.2 0.4 2.0 2 0 0 2 2 1 1 TerY-C metal binding domain zf-RING_4 PF14570.6 KSA01310.1 - 0.0077 16.0 8.9 0.036 13.9 8.9 2.2 1 1 1 2 2 2 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 KSA01310.1 - 0.0097 16.2 5.3 0.028 14.7 5.3 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KSA01310.1 - 0.018 15.1 2.1 0.037 14.1 2.1 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_10 PF16685.5 KSA01310.1 - 0.027 14.6 4.7 0.056 13.6 4.7 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_6 PF14835.6 KSA01310.1 - 0.097 12.6 2.6 0.22 11.4 2.6 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-Nse PF11789.8 KSA01310.1 - 0.26 11.1 7.0 0.67 9.8 7.0 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Zn-ribbon_8 PF09723.10 KSA01310.1 - 0.49 10.6 3.5 2.5 8.3 1.8 2.4 2 0 0 2 2 2 0 Zinc ribbon domain DZR PF12773.7 KSA01310.1 - 3 8.0 6.0 20 5.3 6.6 1.9 1 1 0 1 1 1 0 Double zinc ribbon zf-MIZ PF02891.20 KSA01310.1 - 4.9 7.0 9.7 26 4.6 10.1 2.0 1 1 1 2 2 2 0 MIZ/SP-RING zinc finger Auto_anti-p27 PF06677.12 KSA01310.1 - 8.5 6.6 9.8 1.9 8.7 3.4 2.3 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) ArsA_ATPase PF02374.15 KSA01311.1 - 1.9e-107 359.0 0.3 2.1e-107 358.8 0.3 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 KSA01311.1 - 6e-09 36.0 1.0 2.1e-08 34.3 0.1 2.2 2 1 0 2 2 2 1 AAA domain CbiA PF01656.23 KSA01311.1 - 1.3e-07 31.7 0.9 4.4e-07 30.0 0.4 2.2 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 KSA01311.1 - 0.00023 20.7 3.7 0.017 14.6 1.7 3.0 2 1 1 3 3 3 1 NUBPL iron-transfer P-loop NTPase Fer4_NifH PF00142.18 KSA01311.1 - 0.0027 17.2 0.1 0.0088 15.5 0.0 1.9 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family NB-ARC PF00931.22 KSA01311.1 - 0.011 15.0 0.0 0.032 13.4 0.0 1.8 1 0 0 1 1 1 0 NB-ARC domain Zeta_toxin PF06414.12 KSA01311.1 - 0.027 13.7 0.0 0.058 12.7 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_24 PF13479.6 KSA01311.1 - 0.039 13.7 0.3 0.32 10.7 0.1 2.3 2 1 0 2 2 2 0 AAA domain SRP54 PF00448.22 KSA01311.1 - 0.045 13.4 0.0 0.11 12.1 0.0 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_16 PF13191.6 KSA01311.1 - 0.18 12.2 0.0 0.33 11.3 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain DLH PF01738.18 KSA01312.1 - 7.8e-31 107.3 0.0 9.8e-31 107.0 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S15 PF02129.18 KSA01312.1 - 0.0028 17.3 0.0 0.0036 17.0 0.0 1.5 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.11 KSA01312.1 - 0.0037 17.2 0.0 0.012 15.5 0.0 1.7 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal LIDHydrolase PF10230.9 KSA01312.1 - 0.0039 16.8 0.0 0.0058 16.2 0.0 1.3 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Peptidase_S9 PF00326.21 KSA01312.1 - 0.023 14.2 0.1 0.093 12.2 0.0 2.0 2 1 0 2 2 2 0 Prolyl oligopeptidase family WD40 PF00400.32 KSA01313.1 - 2.4e-22 78.8 5.7 1.9e-05 25.3 0.3 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KSA01313.1 - 4.6e-12 46.1 0.0 0.00091 19.5 0.0 5.5 2 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KSA01313.1 - 0.044 12.8 1.5 8.2 5.3 0.0 3.3 2 1 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein SdiA-regulated PF06977.11 KSA01313.1 - 0.076 12.2 0.0 7.3 5.7 0.0 2.9 3 0 0 3 3 3 0 SdiA-regulated Peptidase_C71 PF12386.8 KSA01314.1 - 0.063 12.9 0.0 0.099 12.3 0.0 1.4 1 0 0 1 1 1 0 Pseudomurein endo-isopeptidase Pei DUF1840 PF08895.11 KSA01314.1 - 9.3 6.6 8.5 28 5.1 8.6 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF1840) SNF2_N PF00176.23 KSA01315.1 - 4.1e-51 173.8 0.0 1.2e-50 172.2 0.0 1.7 1 1 1 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KSA01315.1 - 2.8e-15 56.6 0.0 1.1e-14 54.7 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KSA01315.1 - 4.9e-09 36.4 1.3 2.7e-08 34.0 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 KSA01315.1 - 1.4e-08 34.4 10.0 1.4e-08 34.4 10.0 2.7 3 1 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.29 KSA01315.1 - 1.7e-07 31.2 0.0 3.2e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4_2 PF13923.6 KSA01315.1 - 3e-05 23.7 9.3 3e-05 23.7 9.3 2.5 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KSA01315.1 - 0.0015 18.6 9.5 0.0015 18.6 9.5 2.4 3 0 0 3 3 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 KSA01315.1 - 0.003 17.4 7.3 0.003 17.4 7.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KSA01315.1 - 0.0058 16.6 6.0 0.0058 16.6 6.0 2.3 2 1 0 2 2 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 KSA01315.1 - 0.0064 16.8 9.7 0.0064 16.8 9.7 2.8 3 0 0 3 3 2 1 Ring finger domain Nop14 PF04147.12 KSA01315.1 - 0.0088 14.3 16.4 0.013 13.8 16.4 1.1 1 0 0 1 1 1 1 Nop14-like family zf-rbx1 PF12678.7 KSA01315.1 - 0.0098 16.2 8.2 0.015 15.5 5.5 2.5 2 0 0 2 2 2 1 RING-H2 zinc finger domain Zn_Tnp_IS91 PF14319.6 KSA01315.1 - 0.019 15.0 1.8 0.019 15.0 1.8 2.5 2 0 0 2 2 2 0 Transposase zinc-binding domain zf-Nse PF11789.8 KSA01315.1 - 0.049 13.5 5.3 0.12 12.3 5.3 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit PSY3 PF16836.5 KSA01315.1 - 0.068 12.7 0.2 0.27 10.7 0.0 2.0 2 0 0 2 2 2 0 Shu complex component Psy3, DNA-binding description zf-RING_6 PF14835.6 KSA01315.1 - 0.36 10.7 2.1 0.98 9.3 2.1 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 KSA01315.1 - 5.4 7.0 19.2 0.026 14.4 7.6 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 NAD_binding_4 PF07993.12 KSA01316.1 - 6.3e-72 241.8 0.0 9.1e-72 241.3 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KSA01316.1 - 8.1e-65 219.1 0.0 1.2e-64 218.5 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 KSA01316.1 - 2.9e-12 46.8 0.0 6.7e-12 45.6 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 KSA01316.1 - 3e-08 33.4 0.0 5e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.6 KSA01316.1 - 1.2e-07 32.6 0.1 3.3e-07 31.2 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Condensation PF00668.20 KSA01316.1 - 1.8e-06 26.9 1.5 2e-05 23.5 1.5 2.5 1 1 0 1 1 1 1 Condensation domain 3Beta_HSD PF01073.19 KSA01316.1 - 1.1e-05 24.6 0.0 4.4e-05 22.6 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KSA01316.1 - 0.001 18.2 0.0 0.0019 17.4 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KSA01316.1 - 0.035 13.5 0.0 0.068 12.6 0.0 1.5 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Endonuclease_5 PF04493.14 KSA01316.1 - 0.13 11.9 0.0 1.2 8.7 0.0 2.2 2 0 0 2 2 2 0 Endonuclease V NAD_binding_10 PF13460.6 KSA01316.1 - 0.14 12.0 0.0 0.52 10.2 0.0 2.0 1 1 0 1 1 1 0 NAD(P)H-binding Exonuc_VII_L PF02601.15 KSA01317.1 - 0.05 13.2 0.5 0.082 12.5 0.5 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Prominin PF05478.11 KSA01317.1 - 0.12 10.4 3.6 0.44 8.4 0.5 1.9 1 1 1 2 2 2 0 Prominin Baculo_PEP_C PF04513.12 KSA01317.1 - 0.21 11.6 5.2 0.057 13.5 1.6 1.9 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Snapin_Pallidin PF14712.6 KSA01317.1 - 0.22 12.0 3.2 0.46 10.9 0.9 2.2 1 1 1 2 2 2 0 Snapin/Pallidin Rab5-bind PF09311.11 KSA01317.1 - 0.33 10.3 3.2 0.48 9.8 3.2 1.1 1 0 0 1 1 1 0 Rabaptin-like protein PDEase_I PF00233.19 KSA01318.1 - 4.4e-54 183.7 4.8 2.7e-49 168.0 0.2 2.3 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase SAM_2 PF07647.17 KSA01319.1 - 0.00065 19.8 0.0 0.0016 18.5 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Synaptobrevin PF00957.21 KSA01320.1 - 1.6e-15 56.7 0.6 2.7e-15 55.9 0.6 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 KSA01320.1 - 7e-12 45.2 0.0 1.3e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain CRISPR_Cas9_WED PF18061.1 KSA01320.1 - 0.026 14.6 0.3 0.044 13.9 0.3 1.5 1 0 0 1 1 1 0 CRISPR-Cas9 WED domain DUF2423 PF10338.9 KSA01321.1 - 1.6e-15 57.1 7.5 1.6e-15 57.1 7.5 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) DASH_Spc19 PF08287.11 KSA01321.1 - 1.7 8.5 12.4 2.2 8.1 12.4 1.1 1 0 0 1 1 1 0 Spc19 AIRC PF00731.20 KSA01322.1 - 2.4e-63 212.1 3.8 3.1e-63 211.8 2.3 1.9 2 0 0 2 2 2 1 AIR carboxylase ATP-grasp PF02222.22 KSA01322.1 - 6.5e-60 201.6 0.0 1.1e-59 200.8 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 KSA01322.1 - 7.9e-18 63.9 0.0 1.6e-17 62.9 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain CPSase_L_D2 PF02786.17 KSA01322.1 - 9.9e-06 25.2 0.0 2e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain 2-Hacid_dh_C PF02826.19 KSA01322.1 - 4.2e-05 23.0 0.0 0.0001 21.8 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KSA01322.1 - 0.001 18.4 1.3 0.0028 17.0 0.1 2.2 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Dala_Dala_lig_C PF07478.13 KSA01322.1 - 0.0014 18.2 0.0 0.0062 16.1 0.0 2.0 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 KSA01322.1 - 0.078 13.0 0.1 0.62 10.1 0.0 2.7 3 1 0 3 3 3 0 ATP-grasp domain CoA_binding_2 PF13380.6 KSA01322.1 - 0.082 13.4 1.7 16 6.0 0.0 3.3 2 1 1 3 3 3 0 CoA binding domain NPV_P10 PF05531.12 KSA01322.1 - 0.27 11.7 1.5 0.41 11.1 0.2 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein TEA PF01285.18 KSA01323.1 - 2.4e-25 88.4 0.8 5.2e-25 87.3 0.1 2.0 2 0 0 2 2 2 1 TEA/ATTS domain zf-HC5HC2H_2 PF13832.6 KSA01324.1 - 4.9e-31 107.2 8.1 4.9e-31 107.2 8.1 2.5 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KSA01324.1 - 4.4e-28 97.4 6.1 4.4e-28 97.4 6.1 3.8 4 0 0 4 4 4 1 PHD-like zinc-binding domain EPL1 PF10513.9 KSA01324.1 - 2.7e-15 57.1 8.6 2.7e-15 57.1 8.6 2.6 3 0 0 3 3 3 1 Enhancer of polycomb-like PHD_2 PF13831.6 KSA01324.1 - 8.1e-14 50.9 2.1 8.1e-14 50.9 2.1 2.3 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 KSA01324.1 - 2.2e-09 37.1 9.9 2.2e-09 37.1 9.9 2.8 2 0 0 2 2 2 1 PHD-finger Bromodomain PF00439.25 KSA01324.1 - 0.0013 18.8 0.3 0.0073 16.3 0.1 2.4 2 0 0 2 2 2 1 Bromodomain zf-RRPl_C4 PF17026.5 KSA01324.1 - 1.9 8.6 14.4 14 5.9 13.7 2.9 1 1 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type Prok-RING_1 PF14446.6 KSA01324.1 - 9.7 6.2 29.1 0.063 13.2 7.3 3.4 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 Pkinase PF00069.25 KSA01325.1 - 5.6e-68 229.2 0.0 7.5e-68 228.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KSA01325.1 - 1.1e-33 116.7 0.0 1.4e-33 116.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KSA01325.1 - 3.9e-06 26.4 0.0 3e-05 23.5 0.0 2.3 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 KSA01325.1 - 7.8e-05 22.1 0.1 0.00011 21.6 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KSA01325.1 - 0.001 17.9 0.0 0.0017 17.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase YrbL-PhoP_reg PF10707.9 KSA01325.1 - 0.006 16.1 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL EcKinase PF02958.20 KSA01325.1 - 0.075 12.3 0.6 0.29 10.4 0.1 1.8 1 1 0 2 2 2 0 Ecdysteroid kinase Choline_kinase PF01633.20 KSA01325.1 - 0.13 11.8 0.7 0.25 10.9 0.5 1.5 1 1 0 1 1 1 0 Choline/ethanolamine kinase CBF PF03914.17 KSA01326.1 - 1.1e-47 162.3 0.1 1.1e-47 162.3 0.1 4.5 4 1 0 4 4 4 1 CBF/Mak21 family Nop14 PF04147.12 KSA01326.1 - 1e-06 27.3 48.7 1e-06 27.3 48.7 4.0 3 1 1 4 4 4 1 Nop14-like family CDC45 PF02724.14 KSA01326.1 - 0.0024 16.2 19.6 0.0024 16.2 19.6 5.0 4 1 0 4 4 4 1 CDC45-like protein Ras PF00071.22 KSA01327.1 - 4.6e-27 94.6 0.0 7.4e-27 93.9 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KSA01327.1 - 0.042 14.1 0.3 0.12 12.6 0.0 1.9 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Pkinase PF00069.25 KSA01328.1 - 2.3e-61 207.5 0.0 5.7e-61 206.2 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KSA01328.1 - 6.4e-36 124.0 0.0 1.2e-35 123.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.16 KSA01328.1 - 1.5e-21 76.3 15.1 4.5e-12 45.9 3.7 2.5 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.22 KSA01328.1 - 3.5e-16 58.8 44.0 7.3e-11 41.8 16.4 3.1 3 0 0 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 KSA01328.1 - 2.1e-13 50.7 2.1 9.4e-13 48.6 2.1 2.3 1 0 0 1 1 1 1 Protein kinase C terminal domain C2 PF00168.30 KSA01328.1 - 7.6e-07 29.4 0.2 1e-05 25.8 0.0 2.4 2 0 0 2 2 2 1 C2 domain Haspin_kinase PF12330.8 KSA01328.1 - 0.0025 16.8 4.5 0.017 14.1 4.5 2.5 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KSA01328.1 - 0.011 14.5 0.0 0.021 13.6 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase Uds1 PF15456.6 KSA01328.1 - 0.46 10.7 3.9 0.35 11.0 0.1 2.5 2 0 0 2 2 2 0 Up-regulated During Septation zinc_ribbon_16 PF17034.5 KSA01329.1 - 1.6e-28 99.4 14.6 6.1e-28 97.5 14.4 2.2 1 1 1 2 2 2 1 Zinc-ribbon like family Pkinase PF00069.25 KSA01330.1 - 1.3e-71 241.1 0.8 2.6e-71 240.1 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KSA01330.1 - 3.6e-36 124.8 0.0 1.8e-35 122.5 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Fungal_KA1 PF16797.5 KSA01330.1 - 8.5e-11 41.6 1.1 2.3e-10 40.2 1.1 1.8 1 0 0 1 1 1 1 Fungal kinase associated-1 domain Kinase-like PF14531.6 KSA01330.1 - 0.00094 18.6 0.0 0.002 17.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KSA01330.1 - 0.014 14.7 0.1 0.014 14.7 0.1 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KSA01330.1 - 0.083 12.8 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 KSA01331.1 - 8.9e-70 235.1 0.0 1.3e-69 234.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KSA01331.1 - 1.1e-31 110.0 0.0 1.7e-31 109.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 KSA01331.1 - 1.5e-11 44.8 1.7 4.5e-11 43.3 1.7 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 KSA01331.1 - 2.8e-06 26.5 0.7 5.4e-06 25.6 0.7 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KSA01331.1 - 0.0023 17.3 0.1 0.0053 16.1 0.0 1.6 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 KSA01331.1 - 0.0031 17.2 0.1 2.9 7.5 0.0 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KSA01331.1 - 0.0046 16.3 0.1 0.012 15.0 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KSA01331.1 - 0.15 11.9 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family CK1gamma_C PF12605.8 KSA01331.1 - 0.16 13.2 7.3 0.44 11.7 7.3 1.8 1 0 0 1 1 1 0 Casein kinase 1 gamma C terminal zf-NPL4 PF05020.15 KSA01331.1 - 0.18 11.9 0.0 0.34 11.0 0.0 1.4 1 0 0 1 1 1 0 NPL4 family, putative zinc binding region GRP PF07172.11 KSA01332.1 - 8.2 7.2 13.4 7.6 7.3 7.8 2.2 2 0 0 2 2 2 0 Glycine rich protein family MRP-L28 PF09812.9 KSA01333.1 - 1.8e-30 106.2 3.4 2e-30 106.0 3.4 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 FTA4 PF13093.6 KSA01333.1 - 0.0083 16.0 1.4 0.011 15.7 1.4 1.1 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 PVL_ORF50 PF07768.11 KSA01333.1 - 0.018 15.4 1.0 0.03 14.7 1.0 1.4 1 0 0 1 1 1 0 PVL ORF-50-like family DUF4337 PF14235.6 KSA01333.1 - 0.031 14.4 0.5 0.038 14.1 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) RsbRD_N PF14361.6 KSA01333.1 - 0.032 14.9 0.2 1.5 9.5 0.0 2.1 2 0 0 2 2 2 0 RsbT co-antagonist protein rsbRD N-terminal domain NuA4 PF09340.10 KSA01334.1 - 7.1e-26 89.9 2.6 7.1e-26 89.9 2.6 1.8 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 Rsbr_N PF08678.10 KSA01334.1 - 0.029 14.4 3.3 1.8 8.6 1.2 2.1 1 1 1 2 2 2 0 Rsbr N terminal Enolase_C PF00113.22 KSA01335.1 - 1.8e-155 516.6 0.2 3e-155 515.8 0.0 1.4 2 0 0 2 2 2 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 KSA01335.1 - 7.1e-56 188.0 0.1 2.4e-55 186.2 0.0 1.9 2 0 0 2 2 2 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 KSA01335.1 - 0.00015 21.4 0.0 0.00023 20.8 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 KSA01335.1 - 0.066 12.4 0.3 0.25 10.5 0.1 1.9 2 1 0 2 2 2 0 Methylaspartate ammonia-lyase C-terminus Aminotran_5 PF00266.19 KSA01336.1 - 1.1e-11 44.3 0.0 2.2e-11 43.4 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V Clat_adaptor_s PF01217.20 KSA01337.1 - 4.1e-44 150.0 0.6 4.9e-44 149.7 0.6 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain CBP4 PF07960.11 KSA01338.1 - 1.2e-52 177.1 4.0 1.4e-52 177.0 4.0 1.0 1 0 0 1 1 1 1 CBP4 DUF4574 PF15141.6 KSA01338.1 - 0.00077 19.3 0.6 0.0015 18.4 0.0 1.7 2 0 0 2 2 2 1 Ubiquinol-cytochrome-c reductase complex assembly factor 3 Tmemb_161AB PF10268.9 KSA01338.1 - 0.26 9.9 0.0 0.35 9.5 0.0 1.1 1 0 0 1 1 1 0 Predicted transmembrane protein 161AB TMA7 PF09072.10 KSA01338.1 - 0.59 11.0 5.6 2 9.3 0.3 2.2 2 0 0 2 2 2 0 Translation machinery associated TMA7 Complex1_LYR PF05347.15 KSA01338.1 - 0.7 10.0 4.2 0.31 11.1 0.5 2.2 2 1 0 2 2 2 0 Complex 1 protein (LYR family) LAMTOR PF15454.6 KSA01338.1 - 1.1 9.9 3.6 3.8 8.2 0.4 2.1 2 0 0 2 2 2 0 Late endosomal/lysosomal adaptor and MAPK and MTOR activator Fungal_trans_2 PF11951.8 KSA01339.1 - 4.8e-10 38.8 0.3 7.9e-10 38.1 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KSA01339.1 - 5.6e-08 32.8 9.5 5.6e-08 32.8 9.5 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Corazonin PF17308.2 KSA01339.1 - 0.048 14.0 1.6 0.15 12.4 1.6 1.8 1 0 0 1 1 1 0 Pro-corazonin Ras PF00071.22 KSA01340.1 - 5.9e-50 169.0 0.0 6.8e-50 168.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KSA01340.1 - 3.9e-18 65.8 0.0 5.7e-18 65.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KSA01340.1 - 1.2e-06 28.0 0.0 1.6e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family HMG_box PF00505.19 KSA01341.1 - 2.2e-05 24.8 10.8 0.00095 19.5 5.5 5.3 4 2 1 5 5 5 2 HMG (high mobility group) box HMG_box_2 PF09011.10 KSA01341.1 - 0.0072 16.9 4.6 0.0072 16.9 4.6 5.6 3 3 0 3 3 3 2 HMG-box domain Cpn60_TCP1 PF00118.24 KSA01342.1 - 2e-153 511.6 18.4 2.2e-153 511.4 18.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Sua5_yciO_yrdC PF01300.18 KSA01342.1 - 0.047 13.2 0.0 0.15 11.6 0.0 1.9 1 1 0 1 1 1 0 Telomere recombination UPF0270 PF06794.12 KSA01342.1 - 0.11 12.6 0.0 0.48 10.5 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0270) Cyclin_N PF00134.23 KSA01343.1 - 2.4e-13 49.9 0.0 3.7e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 KSA01343.1 - 2.8e-08 34.3 1.7 6.6e-08 33.1 0.0 2.1 2 0 0 2 2 2 1 Cyclin Na_Ca_ex PF01699.24 KSA01344.1 - 4.6e-45 153.3 36.6 7.3e-23 81.2 20.0 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF2489 PF10675.9 KSA01344.1 - 0.13 12.2 0.0 0.63 10.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2489) ATP-synt_8 PF00895.20 KSA01344.1 - 0.16 12.4 0.3 1.3 9.6 0.0 2.7 2 0 0 2 2 2 0 ATP synthase protein 8 7tm_3 PF00003.22 KSA01344.1 - 0.32 10.7 21.8 0.046 13.5 4.2 3.5 1 1 1 2 2 2 0 7 transmembrane sweet-taste receptor of 3 GCPR DUF2157 PF09925.9 KSA01344.1 - 4.6 7.0 11.1 0.73 9.6 3.1 3.1 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) SE PF08491.10 KSA01345.1 - 1.2e-125 418.2 0.0 1.5e-125 417.8 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 KSA01345.1 - 3.3e-17 62.8 0.0 5.6e-17 62.0 0.0 1.3 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KSA01345.1 - 2.7e-10 40.4 0.4 1.6e-05 24.7 0.7 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KSA01345.1 - 2.3e-05 24.0 2.8 0.00028 20.4 2.8 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KSA01345.1 - 3e-05 24.2 0.1 0.00015 21.9 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KSA01345.1 - 0.00047 19.4 0.3 0.036 13.2 0.1 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KSA01345.1 - 0.00061 19.0 0.4 0.0015 17.6 0.2 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 KSA01345.1 - 0.00064 20.2 0.1 0.023 15.2 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 KSA01345.1 - 0.0007 19.5 0.1 0.0014 18.6 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.17 KSA01345.1 - 0.0019 17.5 0.2 0.0041 16.4 0.1 1.5 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.14 KSA01345.1 - 0.0062 15.8 0.1 0.016 14.5 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KSA01345.1 - 0.011 15.8 0.2 0.028 14.5 0.1 1.7 2 0 0 2 2 1 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 KSA01345.1 - 0.012 15.9 0.1 0.025 14.8 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain Trp_halogenase PF04820.14 KSA01345.1 - 0.017 14.0 0.6 0.39 9.5 0.5 2.0 2 0 0 2 2 2 0 Tryptophan halogenase HI0933_like PF03486.14 KSA01345.1 - 0.023 13.4 0.0 0.041 12.6 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein ApbA PF02558.16 KSA01345.1 - 0.049 13.3 0.0 0.092 12.4 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.14 KSA01345.1 - 0.066 12.8 0.1 0.18 11.4 0.1 1.7 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GDI PF00996.18 KSA01345.1 - 0.14 10.6 0.0 0.24 9.9 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor Sacchrp_dh_NADP PF03435.18 KSA01345.1 - 0.19 12.0 0.2 0.4 11.0 0.2 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Lycopene_cycl PF05834.12 KSA01345.1 - 0.22 10.5 0.1 0.37 9.8 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein W2 PF02020.18 KSA01346.1 - 7e-20 70.9 6.9 2.3e-19 69.3 6.9 2.0 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon NTP_transferase PF00483.23 KSA01346.1 - 8.9e-11 41.8 0.1 2.2e-10 40.6 0.0 1.7 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.24 KSA01346.1 - 1.5e-10 40.4 23.2 0.0002 21.0 3.5 3.8 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 KSA01346.1 - 0.0022 17.0 1.4 0.0038 16.2 1.4 1.4 1 0 0 1 1 1 1 L-fucokinase NTP_transf_3 PF12804.7 KSA01346.1 - 0.0088 16.4 0.0 0.015 15.7 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain YfdX PF10938.8 KSA01346.1 - 0.085 12.8 1.0 0.15 12.0 0.2 1.8 2 0 0 2 2 2 0 YfdX protein Hexapep_2 PF14602.6 KSA01346.1 - 4.8 7.0 21.1 6.6 6.6 3.3 3.7 1 1 3 4 4 4 0 Hexapeptide repeat of succinyl-transferase Ctr PF04145.15 KSA01348.1 - 4.7e-15 56.5 4.8 4.7e-15 56.5 4.8 1.3 1 1 0 1 1 1 1 Ctr copper transporter family U3_assoc_6 PF08640.11 KSA01349.1 - 4e-30 103.7 5.5 6.4e-29 99.9 0.5 3.0 3 0 0 3 3 3 2 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.6 KSA01349.1 - 2.3e-07 31.1 0.1 0.0026 18.4 0.0 3.3 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 KSA01349.1 - 0.00011 22.3 0.2 0.14 12.6 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat NRDE-2 PF08424.10 KSA01349.1 - 0.0023 17.1 2.7 1.9 7.5 0.0 3.8 2 1 2 4 4 4 1 NRDE-2, necessary for RNA interference Suf PF05843.14 KSA01349.1 - 0.014 15.4 0.6 1.4 8.8 0.0 3.0 2 1 1 3 3 3 0 Suppressor of forked protein (Suf) HAT PF02184.16 KSA01349.1 - 0.014 15.3 0.1 12 6.0 0.0 3.7 3 0 0 3 3 3 0 HAT (Half-A-TPR) repeat TPR_11 PF13414.6 KSA01349.1 - 0.06 13.0 0.0 7.3 6.4 0.1 2.5 2 0 0 2 2 2 0 TPR repeat ZZ PF00569.17 KSA01351.1 - 9.5e-15 54.1 8.0 1.7e-14 53.4 8.0 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type SWIRM PF04433.17 KSA01351.1 - 6.3e-14 52.1 2.4 2.5e-13 50.2 0.1 3.0 3 1 1 4 4 4 1 SWIRM domain Myb_DNA-binding PF00249.31 KSA01351.1 - 1.6e-10 41.0 0.4 4.2e-10 39.7 0.0 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KSA01351.1 - 4.9e-06 26.7 0.1 1.6e-05 25.1 0.0 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain Baculo_IE-1 PF05290.11 KSA01351.1 - 0.23 11.4 5.6 0.49 10.3 5.6 1.5 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Ribosomal_S17e PF00833.18 KSA01352.1 - 9.5e-56 187.0 0.6 1.1e-55 186.8 0.6 1.0 1 0 0 1 1 1 1 Ribosomal S17 UPF0262 PF06793.12 KSA01352.1 - 0.0072 16.4 0.1 0.041 14.0 0.1 2.0 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0262) MIR PF02815.19 KSA01352.1 - 0.084 12.7 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 MIR domain ECM11 PF15463.6 KSA01353.1 - 1.3e-09 38.7 0.0 2.6e-09 37.7 0.0 1.7 1 1 0 1 1 1 1 Extracellular mutant protein 11 OSCP PF00213.18 KSA01353.1 - 0.024 14.8 0.7 0.45 10.6 0.1 2.3 2 1 0 2 2 2 0 ATP synthase delta (OSCP) subunit SurA_N PF09312.11 KSA01353.1 - 0.074 13.1 2.8 1.2 9.2 0.2 3.3 2 2 2 4 4 4 0 SurA N-terminal domain DAO PF01266.24 KSA01354.1 - 2.5e-68 231.3 0.0 2.9e-68 231.0 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KSA01354.1 - 1.8e-05 24.8 0.1 3.7e-05 23.9 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KSA01354.1 - 6.1e-05 22.4 0.1 0.018 14.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 KSA01354.1 - 0.0005 19.0 0.1 0.00092 18.1 0.1 1.4 1 0 0 1 1 1 1 MCRA family Thi4 PF01946.17 KSA01354.1 - 0.0038 16.5 0.2 0.0067 15.7 0.2 1.3 1 0 0 1 1 1 1 Thi4 family Sacchrp_dh_NADP PF03435.18 KSA01354.1 - 0.0054 17.0 0.2 0.013 15.8 0.2 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_9 PF13454.6 KSA01354.1 - 0.0065 16.5 0.1 0.033 14.2 0.1 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding ABC_membrane_2 PF06472.15 KSA01356.1 - 1.6e-87 293.4 4.2 3e-87 292.5 4.2 1.5 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 KSA01356.1 - 4.5e-19 69.3 0.0 2.3e-18 67.0 0.0 2.2 2 0 0 2 2 2 1 ABC transporter AAA_23 PF13476.6 KSA01356.1 - 1.1e-06 29.2 3.4 1.1e-06 29.2 3.4 2.2 2 1 0 2 2 2 1 AAA domain SMC_N PF02463.19 KSA01356.1 - 0.0022 17.5 0.4 1.2 8.6 0.1 2.5 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain IstB_IS21 PF01695.17 KSA01356.1 - 0.0032 17.2 0.1 0.1 12.3 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA PF00004.29 KSA01356.1 - 0.0054 17.1 0.1 0.023 15.1 0.1 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.6 KSA01356.1 - 0.014 15.2 0.0 0.014 15.2 0.0 3.6 3 1 1 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system ATPase_2 PF01637.18 KSA01356.1 - 0.014 15.3 0.2 0.045 13.6 0.2 1.9 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 KSA01356.1 - 0.017 14.6 0.0 0.036 13.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 KSA01356.1 - 0.017 15.1 0.1 0.19 11.8 0.1 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 KSA01356.1 - 0.019 14.7 0.0 0.083 12.6 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain PhoH PF02562.16 KSA01356.1 - 0.022 14.2 0.1 1.5 8.3 0.0 3.0 3 0 0 3 3 3 0 PhoH-like protein Mg_chelatase PF01078.21 KSA01356.1 - 0.024 14.0 0.0 0.045 13.1 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.6 KSA01356.1 - 0.031 14.4 0.0 0.071 13.2 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Rad17 PF03215.15 KSA01356.1 - 0.031 14.2 0.0 0.11 12.4 0.0 1.9 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_16 PF13191.6 KSA01356.1 - 0.16 12.3 0.0 0.37 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.6 KSA01356.1 - 0.18 11.9 1.3 11 6.1 0.3 3.4 1 1 1 2 2 2 0 AAA domain NAP PF00956.18 KSA01357.1 - 1.8e-91 306.1 15.6 2.4e-91 305.7 15.6 1.2 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) FAM60A PF15396.6 KSA01357.1 - 2 8.4 4.9 12 5.8 0.7 2.3 2 0 0 2 2 2 0 Protein Family FAM60A Adeno_terminal PF02459.15 KSA01357.1 - 2.5 6.4 12.8 1.5 7.2 0.6 2.2 2 0 0 2 2 2 0 Adenoviral DNA terminal protein DUF3464 PF11947.8 KSA01357.1 - 4.2 7.1 6.6 1.4 8.7 0.9 2.5 2 1 0 2 2 2 0 Photosynthesis affected mutant 68 Gp-FAR-1 PF05823.12 KSA01358.1 - 0.012 15.9 1.9 0.037 14.4 1.9 1.8 1 1 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF2385 PF09539.10 KSA01358.1 - 0.016 15.7 0.4 0.058 13.9 0.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2385) BAR_3 PF16746.5 KSA01358.1 - 0.22 11.2 4.1 0.063 13.0 1.3 1.5 2 0 0 2 2 2 0 BAR domain of APPL family YtxH PF12732.7 KSA01358.1 - 1.1 9.8 4.6 2.6 8.6 0.5 2.4 1 1 0 2 2 2 0 YtxH-like protein Polysacc_deac_1 PF01522.21 KSA01359.1 - 8.7e-24 83.8 0.0 1.6e-23 82.9 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 KSA01359.1 - 0.0046 16.2 0.0 0.0066 15.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 TSC22 PF01166.18 KSA01360.1 - 0.091 13.1 7.2 1.8 8.9 2.2 3.0 2 1 0 2 2 2 0 TSC-22/dip/bun family UPF0449 PF15136.6 KSA01360.1 - 0.17 12.4 1.8 0.53 10.8 1.8 1.9 1 1 0 1 1 1 0 Uncharacterised protein family UPF0449 YabA PF06156.13 KSA01360.1 - 8.7 7.0 8.6 2.3 8.9 2.4 2.6 2 1 1 3 3 3 0 Initiation control protein YabA HAT_KAT11 PF08214.11 KSA01361.1 - 6.7e-112 374.3 0.2 2.7e-111 372.2 0.0 1.8 1 1 1 2 2 2 1 Histone acetylation protein Anp1 PF03452.14 KSA01362.1 - 7.4e-64 215.7 1.1 7.4e-64 215.7 1.1 1.3 2 0 0 2 2 2 1 Anp1 Saw1 PF11561.8 KSA01363.1 - 1.9e-08 34.1 6.9 2.5e-08 33.8 6.7 1.4 1 1 0 1 1 1 1 Single strand annealing-weakened 1 Dynamin_M PF01031.20 KSA01364.1 - 6.6e-108 360.2 0.0 6.6e-108 360.2 0.0 1.8 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 KSA01364.1 - 3.6e-54 183.3 1.0 5.3e-53 179.5 0.0 2.6 2 0 0 2 2 2 1 Dynamin family GED PF02212.18 KSA01364.1 - 8.9e-29 99.5 6.5 2.2e-28 98.2 6.5 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KSA01364.1 - 0.00032 20.7 0.2 0.0062 16.6 0.2 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KSA01364.1 - 0.015 14.8 0.2 4.5 6.8 0.1 2.6 2 0 0 2 2 2 0 Ferrous iron transport protein B bZIP_C PF12498.8 KSA01364.1 - 1.5 9.8 4.7 4.3 8.3 4.7 1.8 1 0 0 1 1 1 0 Basic leucine-zipper C terminal Ribophorin_I PF04597.14 KSA01365.1 - 3.6e-119 398.8 9.9 4.2e-119 398.6 9.9 1.0 1 0 0 1 1 1 1 Ribophorin I RRM_1 PF00076.22 KSA01366.1 - 6e-17 61.2 0.0 9.8e-17 60.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KSA01366.1 - 0.0014 18.2 0.1 0.0015 18.1 0.1 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KSA01366.1 - 0.011 15.6 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif SMN PF06003.12 KSA01366.1 - 0.16 11.2 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Pro_isomerase PF00160.21 KSA01367.1 - 6e-38 130.6 0.4 8.3e-38 130.1 0.4 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Proteasome PF00227.26 KSA01368.1 - 2.4e-47 160.9 0.4 2.8e-47 160.7 0.4 1.0 1 0 0 1 1 1 1 Proteasome subunit AA_permease PF00324.21 KSA01369.1 - 1.2e-146 489.1 40.7 1.5e-146 488.8 40.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KSA01369.1 - 2.1e-36 125.7 43.0 2.9e-36 125.2 43.0 1.1 1 0 0 1 1 1 1 Amino acid permease Mannosyl_trans3 PF11051.8 KSA01370.1 - 2.6e-78 263.1 0.4 4.7e-78 262.3 0.4 1.4 1 0 0 1 1 1 1 Mannosyltransferase putative Glyco_transf_8 PF01501.20 KSA01370.1 - 0.003 17.2 0.8 0.023 14.2 0.3 2.5 1 1 1 2 2 2 1 Glycosyl transferase family 8 Methyltransf_4 PF02390.17 KSA01370.1 - 0.03 13.8 0.1 0.088 12.3 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase ORC3_N PF07034.11 KSA01371.1 - 3.2e-35 121.8 1.6 5.8e-35 121.0 1.6 1.4 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus ORC_WH_C PF18137.1 KSA01371.1 - 1.3e-22 80.4 1.1 2.9e-21 76.0 0.0 2.5 2 0 0 2 2 2 1 Origin recognition complex winged helix C-terminal ATP_bind_2 PF03668.15 KSA01371.1 - 0.009 15.3 0.1 0.021 14.1 0.1 1.6 1 0 0 1 1 1 1 P-loop ATPase protein family PikAIV_N PF18605.1 KSA01371.1 - 0.2 11.3 0.4 9.5 5.9 0.4 2.5 2 0 0 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain POX PF07526.11 KSA01371.1 - 0.52 10.9 2.6 0.54 10.8 0.4 2.1 2 0 0 2 2 2 0 Associated with HOX DAGAT PF03982.13 KSA01372.1 - 3.1e-56 190.5 16.0 6.5e-26 90.9 0.0 5.1 4 1 0 4 4 4 4 Diacylglycerol acyltransferase RNA_pol_Rpc4 PF05132.14 KSA01372.1 - 0.77 10.2 0.0 0.77 10.2 0.0 3.7 3 1 0 3 3 3 0 RNA polymerase III RPC4 UPF0449 PF15136.6 KSA01373.1 - 1.3 9.6 6.6 6 7.4 0.2 2.6 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 PNP_UDP_1 PF01048.20 KSA01374.1 - 3.3e-37 128.0 0.0 3.9e-37 127.8 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily PTR2 PF00854.21 KSA01376.1 - 1.3e-96 323.9 13.5 4.8e-96 322.0 13.5 1.7 1 1 0 1 1 1 1 POT family MFS_1 PF07690.16 KSA01376.1 - 0.079 11.9 30.7 2 7.2 30.6 2.8 1 1 0 1 1 1 0 Major Facilitator Superfamily Pkinase PF00069.25 KSA01377.1 - 1.9e-78 263.5 0.0 3e-78 262.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KSA01377.1 - 1.4e-37 129.4 0.0 2.1e-37 128.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 KSA01377.1 - 8e-27 93.4 5.1 7.4e-14 51.9 0.1 3.3 3 0 0 3 3 3 2 FHA domain Yop-YscD_cpl PF16697.5 KSA01377.1 - 4.3e-09 36.6 0.0 0.002 18.4 0.0 2.9 2 0 0 2 2 2 2 Inner membrane component of T3SS, cytoplasmic domain FHA_2 PF17913.1 KSA01377.1 - 2.2e-08 34.2 0.2 0.0001 22.5 0.0 3.5 3 0 0 3 3 3 2 FHA domain Kinase-like PF14531.6 KSA01377.1 - 8.9e-08 31.8 0.0 1.8e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KSA01377.1 - 7.6e-06 26.0 0.0 0.056 13.4 0.1 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KSA01377.1 - 0.00019 20.8 0.0 0.00037 19.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KSA01377.1 - 0.0045 16.6 0.1 0.0097 15.5 0.1 1.5 1 0 0 1 1 1 1 RIO1 family MFS_1 PF07690.16 KSA01378.1 - 7.4e-33 113.9 23.8 1.4e-31 109.7 24.8 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Holin_BhlA PF10960.8 KSA01378.1 - 0.096 12.7 0.0 0.48 10.4 0.0 2.2 1 0 0 1 1 1 0 BhlA holin family MgtC PF02308.16 KSA01378.1 - 2.2 8.7 14.2 0.029 14.7 3.5 3.1 2 1 1 3 3 3 0 MgtC family Kinesin PF00225.23 KSA01379.1 - 7.9e-93 311.0 0.7 7.9e-93 311.0 0.7 1.9 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KSA01379.1 - 1.5e-23 83.3 1.0 4.3e-23 81.9 0.0 2.2 2 0 0 2 2 2 1 Microtubule binding AAA_33 PF13671.6 KSA01379.1 - 0.12 12.5 0.0 0.31 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain COMP PF11598.8 KSA01379.1 - 0.65 10.5 2.5 1.8 9.1 0.5 2.7 2 0 0 2 2 2 0 Cartilage oligomeric matrix protein RRM_1 PF00076.22 KSA01380.1 - 0.038 13.8 0.0 0.11 12.4 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TruD PF01142.18 KSA01381.1 - 4.5e-72 243.1 4.3 2.7e-67 227.4 0.0 4.2 1 1 1 3 3 3 2 tRNA pseudouridine synthase D (TruD) Presenilin PF01080.17 KSA01381.1 - 7.8 5.2 6.5 13 4.4 6.5 1.2 1 0 0 1 1 1 0 Presenilin Rhodanese PF00581.20 KSA01382.1 - 3.6e-14 53.2 0.0 5.2e-08 33.4 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain ThiC-associated PF13667.6 KSA01382.1 - 0.056 13.3 0.0 2 8.3 0.0 2.4 2 0 0 2 2 2 0 ThiC-associated domain Arc_PepC PF06819.11 KSA01382.1 - 0.11 12.6 1.4 10 6.3 0.0 2.7 2 1 0 2 2 2 0 Archaeal Peptidase A24 C-terminal Domain WD40 PF00400.32 KSA01383.1 - 1.6e-33 114.2 34.8 1.8e-08 34.9 2.1 9.6 8 2 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KSA01383.1 - 7.7e-06 26.1 3.2 0.55 10.6 0.1 4.7 4 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KSA01383.1 - 2.2e-05 23.3 3.1 0.00093 18.0 0.1 3.5 2 1 2 4 4 4 1 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 KSA01383.1 - 0.00067 18.3 0.0 0.012 14.1 0.0 2.1 2 0 0 2 2 2 1 Cytochrome D1 heme domain Hira PF07569.11 KSA01383.1 - 0.074 12.8 0.3 28 4.3 0.0 3.1 3 0 0 3 3 3 0 TUP1-like enhancer of split Ist1 PF03398.14 KSA01384.1 - 2.3e-59 200.0 1.9 3.4e-59 199.4 1.9 1.3 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Pkinase PF00069.25 KSA01385.1 - 8.3e-47 159.8 1.5 7.2e-43 146.8 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KSA01385.1 - 1.2e-16 60.8 0.0 3.6e-16 59.2 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KSA01385.1 - 0.045 13.7 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family V_ATPase_I PF01496.19 KSA01385.1 - 4.1 5.2 12.1 6.7 4.5 12.1 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SPX PF03105.19 KSA01385.1 - 6.1 6.6 28.3 0.27 11.1 10.1 2.5 2 0 0 2 2 2 0 SPX domain Sof1 PF04158.14 KSA01386.1 - 3.5e-34 116.9 9.8 6.1e-34 116.2 9.8 1.4 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.32 KSA01386.1 - 1e-28 99.0 11.4 2.4e-05 25.0 0.1 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KSA01386.1 - 8.5e-07 29.2 0.2 0.18 12.2 0.0 4.2 2 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 KSA01386.1 - 0.015 15.3 0.0 2.5 8.2 0.0 3.3 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Ge1_WD40 PF16529.5 KSA01386.1 - 0.029 13.3 0.1 3.1 6.7 0.0 3.1 2 1 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KSA01386.1 - 0.03 13.7 0.1 2.7 7.2 0.1 2.7 2 2 0 2 2 2 0 WD40-like domain NIF PF03031.18 KSA01387.1 - 4.3e-51 172.8 0.2 6e-51 172.3 0.2 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase LRR_4 PF12799.7 KSA01388.1 - 3.7e-15 55.8 62.8 0.00042 20.7 1.7 10.7 8 2 1 10 10 10 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KSA01388.1 - 2e-12 46.7 53.7 0.00041 20.1 3.8 10.6 7 3 4 11 11 11 6 Leucine rich repeat LRR_6 PF13516.6 KSA01388.1 - 1.3e-07 31.1 35.7 0.42 10.8 0.3 12.1 13 1 0 13 13 13 4 Leucine Rich repeat FNIP PF05725.12 KSA01388.1 - 0.00042 20.4 28.5 0.3 11.3 0.9 6.8 7 0 0 7 7 7 4 FNIP Repeat LRR_5 PF13306.6 KSA01388.1 - 0.0066 16.4 0.9 0.13 12.2 0.1 3.0 2 1 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) F-box PF00646.33 KSA01388.1 - 0.033 14.1 0.0 0.087 12.7 0.0 1.8 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 KSA01388.1 - 0.11 12.4 0.1 0.27 11.1 0.1 1.7 1 0 0 1 1 1 0 F-box-like LRR_1 PF00560.33 KSA01388.1 - 1.9 9.3 49.9 27 5.8 0.1 13.5 12 2 0 12 12 12 0 Leucine Rich Repeat Aldolase_II PF00596.21 KSA01390.1 - 2.2e-47 161.4 0.1 2.9e-47 161.0 0.1 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain G6PD_C PF02781.16 KSA01391.1 - 2.3e-106 355.3 0.0 5.2e-106 354.1 0.0 1.5 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 KSA01391.1 - 1.7e-61 208.0 0.1 3e-61 207.2 0.1 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Peptidase_S8 PF00082.22 KSA01392.1 - 8.5e-33 113.9 2.1 2.2e-32 112.5 2.1 1.7 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 KSA01392.1 - 1.2e-21 76.5 0.1 3e-21 75.2 0.1 1.7 1 0 0 1 1 1 1 Proprotein convertase P-domain Peptidase_S8_N PF16361.5 KSA01392.1 - 0.029 14.9 2.2 0.059 13.9 0.0 2.6 2 0 0 2 2 2 0 N-terminal of Subtilase family Trypan_PARP PF05887.11 KSA01392.1 - 0.26 11.2 7.5 0.83 9.6 7.5 1.8 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Ytp1 PF10355.9 KSA01393.1 - 3.7e-65 219.9 17.6 2.2e-64 217.4 15.1 2.5 2 1 0 2 2 2 1 Protein of unknown function (Ytp1) DUF4225 PF13988.6 KSA01393.1 - 0.16 11.5 0.7 0.4 10.2 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4225) Ninjurin PF04923.12 KSA01393.1 - 0.2 11.6 1.3 9.7 6.2 0.4 3.4 3 0 0 3 3 3 0 Ninjurin YobH PF13996.6 KSA01393.1 - 2.2 8.4 5.5 2.3 8.3 0.4 3.1 3 0 0 3 3 3 0 YobH-like protein Fe_hyd_lg_C PF02906.14 KSA01394.1 - 1.8e-62 211.2 0.0 3e-62 210.5 0.0 1.3 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain mIF3 PF14877.6 KSA01395.1 - 2.2e-59 200.1 10.6 2.2e-59 200.1 10.6 3.0 3 0 0 3 3 3 1 Mitochondrial translation initiation factor Solute_trans_a PF03619.16 KSA01396.1 - 2.7e-84 282.8 12.9 3.3e-84 282.5 12.9 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Pkinase PF00069.25 KSA01397.1 - 2.8e-47 161.3 0.0 4.5e-47 160.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KSA01397.1 - 2.5e-20 72.8 0.2 8.3e-20 71.2 0.2 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 KSA01397.1 - 0.00021 21.0 0.6 0.0035 16.9 0.6 2.4 1 1 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 KSA01397.1 - 0.0091 15.3 0.0 0.032 13.6 0.0 1.8 2 0 0 2 2 2 1 Kinase-like DUF4446 PF14584.6 KSA01397.1 - 0.026 14.5 0.0 0.11 12.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) APH PF01636.23 KSA01397.1 - 0.033 14.1 0.0 0.23 11.3 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF21 PF01595.20 KSA01398.1 - 2e-31 109.1 0.0 3.4e-31 108.3 0.0 1.3 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 KSA01398.1 - 0.0035 17.7 0.0 1.3 9.5 0.0 2.7 2 0 0 2 2 2 2 CBS domain MRP-S25 PF13741.6 KSA01399.1 - 2.9e-94 314.9 4.9 3.6e-94 314.6 4.9 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.9 KSA01399.1 - 1.1e-06 28.9 2.0 0.0015 18.8 0.0 3.0 2 1 1 3 3 3 2 Mitochondrial ribosomal protein S23 PPR_2 PF13041.6 KSA01400.1 - 0.0012 19.0 1.3 3.6 7.8 0.0 4.4 4 0 0 4 4 4 2 PPR repeat family PPR_3 PF13812.6 KSA01400.1 - 0.0037 17.3 1.3 0.19 11.8 0.1 3.0 2 0 0 2 2 2 1 Pentatricopeptide repeat domain CEP1-DNA_bind PF09287.10 KSA01400.1 - 0.0043 16.7 0.1 0.0093 15.6 0.1 1.5 1 0 0 1 1 1 1 CEP-1, DNA binding Ank_3 PF13606.6 KSA01400.1 - 0.037 14.6 0.0 0.22 12.2 0.0 2.4 1 0 0 1 1 1 0 Ankyrin repeat ATP13 PF12921.7 KSA01400.1 - 0.046 13.6 2.7 5.4 6.9 0.1 3.4 3 0 0 3 3 3 0 Mitochondrial ATPase expression EF_assoc_2 PF08356.12 KSA01400.1 - 0.047 13.7 0.1 0.2 11.7 0.1 2.1 1 0 0 1 1 1 0 EF hand associated BAG PF02179.16 KSA01400.1 - 0.1 13.1 0.0 0.45 11.0 0.0 2.2 1 0 0 1 1 1 0 BAG domain Chordopox_A13L PF05961.11 KSA01401.1 - 0.01 16.0 0.2 0.037 14.3 0.2 1.9 1 0 0 1 1 1 0 Chordopoxvirus A13L protein O-antigen_lig PF13425.6 KSA01401.1 - 0.6 8.8 2.0 0.73 8.6 2.0 1.3 1 1 0 1 1 1 0 O-antigen ligase like membrane protein Frataxin_Cyay PF01491.16 KSA01402.1 - 2.3e-36 124.2 0.0 2.8e-36 123.9 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain zf-MIZ PF02891.20 KSA01403.1 - 2.7e-08 33.4 2.4 1.7e-06 27.6 0.2 2.4 2 0 0 2 2 2 2 MIZ/SP-RING zinc finger zf-Nse PF11789.8 KSA01403.1 - 0.0019 18.0 2.3 0.0019 18.0 2.3 3.1 2 2 1 3 3 3 1 Zinc-finger of the MIZ type in Nse subunit C2 PF00168.30 KSA01404.1 - 6.9e-62 206.2 4.8 1.7e-15 57.2 0.0 4.4 4 0 0 4 4 4 4 C2 domain RNA_pol_Rpc4 PF05132.14 KSA01404.1 - 0.0075 16.7 0.5 0.023 15.1 0.5 1.8 1 0 0 1 1 1 1 RNA polymerase III RPC4 RNA_pol_Rpb1_5 PF04998.17 KSA01405.1 - 3e-95 318.7 0.1 6.3e-95 317.6 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KSA01405.1 - 2.3e-69 232.9 0.1 5.4e-69 231.7 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 KSA01405.1 - 3.7e-39 134.2 0.2 2.8e-38 131.3 0.0 2.7 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 KSA01405.1 - 8.4e-26 91.0 2.0 2.2e-25 89.6 0.3 2.5 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.17 KSA01405.1 - 6.4e-24 84.0 0.0 4.8e-23 81.2 0.0 2.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Nop14 PF04147.12 KSA01405.1 - 7.3 4.7 21.9 15 3.6 21.9 1.4 1 0 0 1 1 1 0 Nop14-like family FUN14 PF04930.15 KSA01406.1 - 1e-07 32.2 1.9 1.2e-07 32.0 0.8 1.7 2 0 0 2 2 2 1 FUN14 family DSPc PF00782.20 KSA01407.1 - 2.7e-07 30.5 1.1 0.026 14.3 0.1 3.0 1 1 1 3 3 3 2 Dual specificity phosphatase, catalytic domain TbpB_A PF17484.2 KSA01407.1 - 0.046 14.5 0.1 0.067 13.9 0.1 1.3 1 0 0 1 1 1 0 N-Lobe handle Tf-binding protein B Complex1_LYR_2 PF13233.6 KSA01408.1 - 1.4e-18 67.4 8.5 2.4e-18 66.6 8.5 1.4 1 1 0 1 1 1 1 Complex1_LYR-like Sarcoglycan_1 PF04790.13 KSA01408.1 - 0.03 13.7 0.4 0.036 13.4 0.4 1.1 1 0 0 1 1 1 0 Sarcoglycan complex subunit protein SirA PF10747.9 KSA01408.1 - 0.085 13.2 6.8 0.13 12.6 6.8 1.5 1 1 0 1 1 1 0 Sporulation inhibitor of replication protein SirA Iso_dh PF00180.20 KSA01409.1 - 9e-80 268.4 0.1 1e-79 268.2 0.1 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Adenylsucc_synt PF00709.21 KSA01411.1 - 8.3e-179 594.9 0.0 9.4e-179 594.7 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase Glyco_transf_22 PF03901.17 KSA01412.1 - 3.3e-83 280.3 27.8 4.1e-83 279.9 27.8 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Hpt PF01627.23 KSA01413.1 - 4e-10 39.8 0.0 5.6e-10 39.3 0.0 1.3 1 1 0 1 1 1 1 Hpt domain NADPH_Ox PF08414.10 KSA01413.1 - 0.031 14.6 0.9 0.081 13.3 0.1 1.9 2 0 0 2 2 2 0 Respiratory burst NADPH oxidase pEK499_p136 PF18736.1 KSA01413.1 - 0.04 13.6 0.8 0.13 11.9 0.3 1.8 2 0 0 2 2 2 0 HEPN pEK499 p136 Carb_anhydrase PF00194.21 KSA01413.1 - 0.06 12.9 0.1 0.13 11.8 0.0 1.5 1 1 1 2 2 2 0 Eukaryotic-type carbonic anhydrase Hydrolase_6 PF13344.6 KSA01414.1 - 8.8e-29 99.6 0.0 1.5e-28 98.8 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KSA01414.1 - 2.7e-16 59.4 0.0 8.8e-16 57.7 0.0 1.9 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 KSA01414.1 - 2.4e-07 31.3 0.0 4.4e-07 30.4 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KSA01414.1 - 0.015 15.4 1.1 4.2 7.4 0.0 2.6 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase GRIM-19 PF06212.12 KSA01415.1 - 7.6e-22 77.7 0.2 8.9e-22 77.5 0.2 1.1 1 0 0 1 1 1 1 GRIM-19 protein BRD4_CDT PF17105.5 KSA01415.1 - 4.4 7.0 6.2 6.5 6.4 0.8 2.2 2 0 0 2 2 2 0 C-terminal domain of bromodomain protein 4 GTP_EFTU PF00009.27 KSA01416.1 - 3.6e-33 114.7 0.0 3.6e-33 114.7 0.0 2.8 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 KSA01416.1 - 2.6e-21 75.7 0.5 8.7e-21 74.0 0.0 2.2 2 0 0 2 2 2 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 KSA01416.1 - 9.4e-11 42.0 3.9 1.1e-07 32.1 0.0 3.7 3 0 0 3 3 3 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KSA01416.1 - 2.8e-06 27.4 2.3 1.3e-05 25.2 0.0 3.1 3 0 0 3 3 3 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 KSA01416.1 - 3.1e-06 27.0 0.1 1.5e-05 24.8 0.1 2.3 1 1 0 1 1 1 1 Elongation factor Tu domain 4 Roc PF08477.13 KSA01416.1 - 0.0002 21.6 0.0 0.00069 19.8 0.0 2.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 KSA01416.1 - 0.00036 20.4 0.2 0.002 18.0 0.0 2.4 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein FeoB_N PF02421.18 KSA01416.1 - 0.013 15.0 0.1 0.085 12.4 0.0 2.5 3 0 0 3 3 3 0 Ferrous iron transport protein B DUF211 PF02680.14 KSA01416.1 - 0.12 12.5 1.5 0.41 10.8 1.5 1.9 1 0 0 1 1 1 0 Uncharacterized ArCR, COG1888 AAA_22 PF13401.6 KSA01416.1 - 0.12 12.6 0.7 2.2 8.6 0.7 2.9 1 1 0 1 1 1 0 AAA domain MMR_HSR1_Xtn PF16897.5 KSA01417.1 - 6.9e-39 132.1 0.3 2.9e-38 130.2 0.1 2.0 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 KSA01417.1 - 2.5e-21 75.5 0.0 4.9e-21 74.6 0.0 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 KSA01417.1 - 1.3e-20 73.6 0.2 4.7e-20 71.8 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KSA01417.1 - 2.1e-09 37.1 0.1 4.6e-09 36.0 0.0 1.6 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KSA01417.1 - 0.0061 16.6 0.3 4.9 7.2 0.3 2.4 1 1 1 2 2 2 2 Dynamin family MeaB PF03308.16 KSA01417.1 - 0.011 14.7 0.2 0.022 13.8 0.2 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Importin_rep_6 PF18829.1 KSA01418.1 - 5.2e-39 132.7 3.2 5.2e-39 132.7 3.2 3.3 3 0 0 3 3 3 1 Importin repeat 6 Importin_rep_4 PF18808.1 KSA01418.1 - 2.6e-29 101.3 1.5 2.6e-29 101.3 1.5 4.3 4 0 0 4 4 4 1 Importin repeat HEAT_EZ PF13513.6 KSA01418.1 - 5.2e-25 87.5 13.7 1.6e-11 44.4 0.1 9.1 8 2 2 10 10 10 5 HEAT-like repeat Importin_rep_5 PF18816.1 KSA01418.1 - 9.3e-25 86.7 0.2 8.5e-24 83.6 0.3 2.6 2 0 0 2 2 2 1 Importin repeat HEAT_2 PF13646.6 KSA01418.1 - 1.1e-18 67.4 3.6 1.5e-06 28.5 0.1 8.7 5 2 4 9 9 8 4 HEAT repeats HEAT PF02985.22 KSA01418.1 - 3.8e-18 64.0 13.5 0.0028 17.8 0.0 12.0 12 0 0 12 12 11 3 HEAT repeat Vac14_Fab1_bd PF12755.7 KSA01418.1 - 3.1e-10 40.5 0.2 0.0055 17.3 0.0 6.8 4 2 2 7 7 6 1 Vacuolar 14 Fab1-binding region MMS19_C PF12460.8 KSA01418.1 - 8.9e-09 35.0 12.7 0.013 14.7 0.7 6.0 3 3 3 6 6 6 4 RNAPII transcription regulator C-terminal DUF3385 PF11865.8 KSA01418.1 - 3.6e-08 33.5 0.5 1 9.3 0.1 7.1 5 3 1 6 6 6 1 Domain of unknown function (DUF3385) CLASP_N PF12348.8 KSA01418.1 - 6.6e-08 32.4 7.0 0.72 9.4 0.0 6.9 5 1 1 6 6 6 1 CLASP N terminal RIX1 PF08167.12 KSA01418.1 - 2.2e-06 27.6 4.4 0.021 14.6 0.0 5.5 3 3 1 4 4 4 1 rRNA processing/ribosome biogenesis Tti2 PF10521.9 KSA01418.1 - 1.6e-05 24.6 0.5 0.029 13.9 0.0 3.9 4 1 0 4 4 4 1 Tti2 family RTP1_C1 PF10363.9 KSA01418.1 - 2.2e-05 24.6 1.0 2.4 8.4 0.0 5.5 6 0 0 6 6 5 1 Required for nuclear transport of RNA pol II C-terminus 1 Arm PF00514.23 KSA01418.1 - 2.2e-05 24.3 7.9 0.47 10.6 0.0 6.6 7 0 0 7 7 6 1 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 KSA01418.1 - 2.8e-05 24.2 5.0 0.3 11.1 0.2 5.5 6 0 0 6 6 6 2 non-SMC mitotic condensation complex subunit 1 ParcG PF10274.9 KSA01418.1 - 3.6e-05 24.0 2.7 0.043 13.9 0.0 5.3 5 3 0 5 5 5 1 Parkin co-regulated protein DNA_alkylation PF08713.11 KSA01418.1 - 0.0056 16.4 0.0 0.025 14.3 0.0 2.1 1 0 0 1 1 1 1 DNA alkylation repair enzyme Cnd3 PF12719.7 KSA01418.1 - 0.015 14.5 0.0 0.79 8.9 0.0 3.3 3 0 0 3 3 3 0 Nuclear condensing complex subunits, C-term domain RNA_pol_Rpb2_2 PF04561.14 KSA01418.1 - 0.023 14.4 0.5 0.069 12.8 0.5 1.8 2 0 0 2 2 2 0 RNA polymerase Rpb2, domain 2 HrpE PF06188.12 KSA01418.1 - 0.031 14.1 0.1 0.16 11.8 0.1 2.3 2 0 0 2 2 2 0 HrpE/YscL/FliH and V-type ATPase subunit E HEAT_PBS PF03130.16 KSA01418.1 - 1.1 10.2 5.6 45 5.1 0.0 5.3 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat Telomerase_RBD PF12009.8 KSA01419.1 - 2e-27 95.9 3.9 6.3e-27 94.3 3.0 2.5 2 0 0 2 2 2 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.27 KSA01419.1 - 8.2e-10 38.6 7.1 5.5e-08 32.6 0.3 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) dCMP_cyt_deam_1 PF00383.23 KSA01420.1 - 8.5e-09 35.2 0.3 1.5e-08 34.4 0.3 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KSA01420.1 - 5e-06 26.3 1.6 5e-06 26.3 1.6 2.3 2 1 0 2 2 2 1 MafB19-like deaminase Bd3614-deam PF14439.6 KSA01420.1 - 0.064 13.3 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 Bd3614-like deaminase HypA PF01155.19 KSA01420.1 - 0.19 11.8 0.9 21 5.2 0.1 2.3 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Cnl2_NKP2 PF09447.10 KSA01421.1 - 8e-17 61.2 2.7 1.8e-16 60.0 2.7 1.6 1 0 0 1 1 1 1 Cnl2/NKP2 family protein GCP_C_terminal PF04130.13 KSA01421.1 - 0.0022 17.5 0.6 0.034 13.6 0.4 2.0 1 1 1 2 2 2 1 Gamma tubulin complex component C-terminal PET10 PF17316.2 KSA01421.1 - 0.026 14.0 2.8 0.041 13.4 1.0 1.8 1 1 1 2 2 2 0 Petite colonies protein 10 DUF3349 PF11829.8 KSA01421.1 - 0.051 14.4 1.7 13 6.6 0.2 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3349) TBPIP PF07106.13 KSA01421.1 - 0.081 12.9 0.0 0.29 11.1 0.0 2.0 2 0 0 2 2 2 0 TBPIP/Hop2 winged helix domain SNF5 PF04855.12 KSA01422.1 - 2.3e-50 171.6 3.2 9.7e-30 104.1 0.4 2.3 1 1 1 2 2 2 2 SNF5 / SMARCB1 / INI1 SOP4 PF17081.5 KSA01422.1 - 0.04 13.5 0.2 0.085 12.4 0.2 1.5 1 0 0 1 1 1 0 Suppressor of PMA 1-7 protein SKN1 PF03935.15 KSA01423.1 - 7.7e-21 74.1 0.1 1.3e-20 73.3 0.0 1.4 2 0 0 2 2 2 1 Beta-glucan synthesis-associated protein (SKN1) Caveolin PF01146.17 KSA01423.1 - 0.17 11.8 0.1 0.38 10.7 0.1 1.5 1 0 0 1 1 1 0 Caveolin APG9 PF04109.16 KSA01424.1 - 3.2e-177 590.4 25.5 3.8e-177 590.1 25.5 1.1 1 0 0 1 1 1 1 Autophagy protein Apg9 Nop14 PF04147.12 KSA01425.1 - 2.7e-111 373.3 44.9 5.4e-66 223.5 37.6 2.2 1 1 1 2 2 2 2 Nop14-like family Tugs PF17840.1 KSA01425.1 - 0.056 13.6 1.8 0.093 12.9 0.7 2.0 2 0 0 2 2 2 0 Tethering Ubl4a to BAGS domain Nop14 PF04147.12 KSA01426.1 - 8.7e-37 126.8 13.0 1e-36 126.6 13.0 1.1 1 0 0 1 1 1 1 Nop14-like family Atg14 PF10186.9 KSA01426.1 - 0.76 8.8 10.6 0.92 8.5 10.6 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4407 PF14362.6 KSA01426.1 - 2.3 7.5 6.3 3 7.1 6.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MARVEL PF01284.23 KSA01427.1 - 3.8e-29 101.6 18.3 4.7e-29 101.3 18.3 1.1 1 0 0 1 1 1 1 Membrane-associating domain Sugar_tr PF00083.24 KSA01428.1 - 5.7e-119 397.9 27.0 6.9e-119 397.7 27.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KSA01428.1 - 1.5e-14 53.7 36.1 1.2e-12 47.5 5.5 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily DUF3246 PF11596.8 KSA01428.1 - 0.93 8.9 19.5 0.052 13.0 3.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3246) DUF4611 PF15387.6 KSA01428.1 - 6.2 7.1 9.7 1.4 9.2 0.2 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) DUF5099 PF17025.5 KSA01429.1 - 0.00022 21.6 0.1 0.00042 20.7 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5099) Arf PF00025.21 KSA01430.1 - 1e-79 266.0 0.1 1.2e-79 265.8 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KSA01430.1 - 2.8e-14 53.0 0.0 3.5e-14 52.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 KSA01430.1 - 3.5e-14 53.0 0.0 4.8e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KSA01430.1 - 9.5e-13 48.1 0.0 1.1e-12 47.9 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 KSA01430.1 - 1.6e-12 47.2 2.0 1.3e-08 34.4 0.4 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 KSA01430.1 - 2.4e-10 40.2 0.0 2.9e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KSA01430.1 - 9.5e-06 25.7 0.0 1.6e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 KSA01430.1 - 0.0031 16.9 1.5 0.017 14.4 1.5 1.9 1 1 0 1 1 1 1 6-phosphofructo-2-kinase EcoRI PF02963.16 KSA01430.1 - 0.055 12.5 0.0 0.081 11.9 0.0 1.1 1 0 0 1 1 1 0 Restriction endonuclease EcoRI Ufd2P_core PF10408.9 KSA01431.1 - 7.2e-199 662.4 7.6 8.7e-199 662.2 7.6 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 KSA01431.1 - 1.3e-25 89.3 0.7 3.5e-25 88.0 0.7 1.7 1 0 0 1 1 1 1 U-box domain R3H PF01424.22 KSA01432.1 - 2.2e-05 24.3 0.1 5.2e-05 23.1 0.1 1.6 1 0 0 1 1 1 1 R3H domain CDC45 PF02724.14 KSA01432.1 - 0.054 11.8 6.4 0.078 11.3 6.4 1.1 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 KSA01432.1 - 1.2 8.4 13.9 2.4 7.4 13.9 1.5 1 0 0 1 1 1 0 NOA36 protein FAM176 PF14851.6 KSA01432.1 - 1.4 8.5 8.4 3.3 7.4 8.4 1.6 1 0 0 1 1 1 0 FAM176 family PBP1_TM PF14812.6 KSA01432.1 - 1.5 9.2 11.2 4.4 7.7 11.2 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.10 KSA01432.1 - 2.1 8.8 16.0 8.9 6.8 14.4 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF2457 PF10446.9 KSA01432.1 - 2.3 7.3 18.0 4 6.5 18.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF4637 PF15470.6 KSA01432.1 - 6.4 6.5 8.2 12 5.6 8.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Rho_GDI PF02115.17 KSA01433.1 - 3.7e-57 193.2 0.6 4.4e-57 193.0 0.6 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor UvrD-helicase PF00580.21 KSA01434.1 - 1.7e-59 201.9 1.2 1.7e-59 201.9 1.2 2.9 3 0 0 3 3 3 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 KSA01434.1 - 1.2e-53 182.7 5.2 7.1e-53 180.2 5.2 2.2 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 KSA01434.1 - 9.8e-27 94.1 0.0 1.8e-26 93.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 KSA01434.1 - 1.8e-08 34.1 0.1 1.2e-07 31.4 0.1 2.2 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_11 PF13086.6 KSA01434.1 - 2.9e-08 33.8 0.0 2.9e-08 33.8 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 KSA01434.1 - 2.4e-05 24.2 0.0 0.0012 18.6 0.0 2.3 2 1 0 2 2 2 1 AAA domain DUF3638 PF12340.8 KSA01434.1 - 0.0012 18.3 2.6 1.6 8.0 0.1 3.4 3 0 0 3 3 3 2 Protein of unknown function (DUF3638) Helicase_RecD PF05127.14 KSA01434.1 - 0.0041 17.0 0.0 0.03 14.2 0.0 2.4 2 0 0 2 2 2 1 Helicase DEAD PF00270.29 KSA01434.1 - 0.031 14.1 0.3 0.13 12.0 0.3 2.1 1 0 0 1 1 1 0 DEAD/DEAH box helicase Chordopox_A33R PF05966.12 KSA01434.1 - 0.075 12.3 0.2 0.16 11.3 0.2 1.4 1 0 0 1 1 1 0 Chordopoxvirus A33R protein RNA_binding PF01877.17 KSA01434.1 - 0.69 10.2 5.7 4.4 7.6 0.2 3.9 2 1 1 3 3 3 0 RNA binding Lectin_C PF00059.21 KSA01435.1 - 0.12 13.1 2.4 0.25 12.1 1.0 2.3 2 0 0 2 2 2 0 Lectin C-type domain Band_7 PF01145.25 KSA01436.1 - 6.2e-23 81.7 2.5 9.7e-23 81.1 2.5 1.4 1 1 0 1 1 1 1 SPFH domain / Band 7 family DUF3416 PF11896.8 KSA01436.1 - 0.081 13.2 2.0 0.12 12.7 1.3 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF3416) SH3_1 PF00018.28 KSA01437.1 - 1.4e-14 53.4 0.3 2.4e-14 52.7 0.3 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KSA01437.1 - 1.2e-11 44.2 0.0 1.8e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KSA01437.1 - 1.8e-11 43.7 0.0 3.5e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain WD40 PF00400.32 KSA01438.1 - 6.1e-10 39.5 21.0 0.00017 22.3 0.1 7.1 8 1 0 8 8 8 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KSA01438.1 - 1.2e-07 32.0 1.7 0.47 10.8 0.0 4.4 2 1 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain ICAM_N PF03921.14 KSA01438.1 - 0.052 13.2 1.3 0.6 9.8 0.3 2.5 2 0 0 2 2 2 0 Intercellular adhesion molecule (ICAM), N-terminal domain DIE2_ALG10 PF04922.12 KSA01439.1 - 9.5e-84 282.0 29.7 1.3e-83 281.6 29.7 1.2 1 0 0 1 1 1 1 DIE2/ALG10 family SMI1_KNR4 PF09346.10 KSA01440.1 - 1.4e-44 151.7 0.7 5.7e-44 149.7 0.1 2.2 2 0 0 2 2 2 1 SMI1 / KNR4 family (SUKH-1) SUKH_5 PF14567.6 KSA01440.1 - 0.00046 19.9 0.0 0.047 13.4 0.0 3.0 2 1 0 2 2 2 1 SMI1-KNR4 cell-wall SUKH_6 PF14568.6 KSA01440.1 - 0.0018 18.7 0.9 0.45 11.0 0.2 3.2 2 1 0 2 2 2 1 SMI1-KNR4 cell-wall Ribosomal_S2 PF00318.20 KSA01441.1 - 1.3e-24 86.6 0.2 4.3e-13 49.0 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 KSA01441.1 - 0.00018 22.8 8.9 0.00049 21.4 8.9 1.8 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus MFS_1 PF07690.16 KSA01442.1 - 2.2e-20 72.9 12.4 1.5e-12 47.2 2.6 2.3 2 1 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KSA01442.1 - 0.0011 17.3 0.3 0.018 13.3 0.2 2.2 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family DUF3754 PF12576.8 KSA01442.1 - 0.021 14.8 1.1 0.081 12.9 1.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3754) Gpi1 PF05024.15 KSA01444.1 - 1.5e-62 211.0 25.0 1.5e-62 211.0 25.0 2.6 2 1 0 2 2 2 1 N-acetylglucosaminyl transferase component (Gpi1) MatP PF06303.12 KSA01444.1 - 0.047 14.2 0.1 0.11 13.1 0.1 1.6 1 0 0 1 1 1 0 MatP N-terminal domain FOP_dimer PF09398.10 KSA01445.1 - 0.034 14.4 1.5 1.3 9.3 0.1 3.2 2 0 0 2 2 2 0 FOP N terminal dimerisation domain SRI PF08236.11 KSA01445.1 - 0.08 13.1 5.7 0.062 13.5 2.5 2.4 1 1 1 2 2 2 0 SRI (Set2 Rpb1 interacting) domain OCD_Mu_crystall PF02423.15 KSA01446.1 - 3.9e-20 72.0 0.0 5.1e-20 71.6 0.0 1.1 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 KSA01446.1 - 0.00035 20.6 0.1 0.0012 18.9 0.1 1.9 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Alk_phosphatase PF00245.20 KSA01447.1 - 7.8e-117 390.7 0.0 9.3e-117 390.5 0.0 1.0 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 KSA01447.1 - 4.2e-06 26.3 0.2 9.7e-06 25.1 0.1 1.7 2 0 0 2 2 2 1 Metalloenzyme superfamily MFS_1 PF07690.16 KSA01448.1 - 8.7e-37 126.9 23.3 8.7e-37 126.9 23.3 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Beta_elim_lyase PF01212.21 KSA01449.1 - 7.1e-77 258.6 0.0 8.7e-77 258.3 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 KSA01449.1 - 5.1e-05 22.6 0.0 8.2e-05 21.9 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KSA01449.1 - 0.021 13.8 0.0 0.12 11.3 0.0 2.0 1 1 0 2 2 2 0 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KSA01449.1 - 0.093 12.0 0.0 0.28 10.5 0.0 1.8 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Filament PF00038.21 KSA01450.1 - 0.013 15.1 25.5 0.039 13.5 23.6 2.2 1 1 1 2 2 2 0 Intermediate filament protein fn3 PF00041.21 KSA01450.1 - 0.056 13.8 0.3 0.51 10.7 0.1 2.8 3 0 0 3 3 3 0 Fibronectin type III domain CALCOCO1 PF07888.11 KSA01450.1 - 0.08 11.8 17.8 0.13 11.1 17.8 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF4407 PF14362.6 KSA01450.1 - 0.39 10.0 5.6 0.89 8.8 5.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) APG6_N PF17675.1 KSA01450.1 - 8.2 7.0 28.0 2.7 8.5 10.2 2.8 1 1 2 3 3 3 0 Apg6 coiled-coil region Spc24 PF08286.11 KSA01450.1 - 8.3 6.7 19.9 4.1 7.7 9.3 3.9 4 1 0 4 4 4 0 Spc24 subunit of Ndc80 Phage_holin_3_6 PF07332.11 KSA01451.1 - 2.6 8.1 0.0 2.6 8.1 0.0 4.5 5 0 0 5 5 5 0 Putative Actinobacterial Holin-X, holin superfamily III DUF2838 PF10998.8 KSA01452.1 - 7e-37 126.1 10.7 7e-37 126.1 10.7 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF2838) LEA_4 PF02987.16 KSA01452.1 - 0.072 13.2 1.7 0.14 12.2 1.7 1.4 1 0 0 1 1 1 0 Late embryogenesis abundant protein Uso1_p115_C PF04871.13 KSA01452.1 - 0.73 10.2 10.6 1.3 9.4 0.9 2.4 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region MAS20 PF02064.15 KSA01452.1 - 2.7 8.1 5.5 0.29 11.2 0.3 1.9 2 0 0 2 2 2 0 MAS20 protein import receptor ZapB PF06005.12 KSA01452.1 - 2.8 8.4 10.8 0.28 11.7 3.4 2.3 2 0 0 2 2 2 0 Cell division protein ZapB DivIC PF04977.15 KSA01452.1 - 3 7.7 7.9 1.3 8.9 0.2 3.0 3 0 0 3 3 3 0 Septum formation initiator Git3 PF11710.8 KSA01453.1 - 4.5e-84 281.3 12.9 8.2e-84 280.4 12.9 1.4 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 KSA01453.1 - 6.9e-32 109.4 1.2 6.9e-32 109.4 1.2 2.5 3 0 0 3 3 3 1 G protein-coupled glucose receptor regulating Gpa2 C-term STE3 PF02076.15 KSA01453.1 - 0.0023 17.2 7.6 0.0063 15.8 7.5 1.8 1 1 0 1 1 1 1 Pheromone A receptor 7tm_1 PF00001.21 KSA01453.1 - 0.051 12.9 6.6 0.077 12.3 6.6 1.3 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Wzy_C PF04932.15 KSA01453.1 - 0.94 9.1 7.5 1.5 8.4 0.1 2.9 1 1 1 2 2 2 0 O-Antigen ligase DUF3021 PF11457.8 KSA01453.1 - 6.9 7.0 11.7 7.7 6.9 0.5 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3021) Ribosomal_S5_C PF03719.15 KSA01454.1 - 9.1e-25 85.9 0.0 2.9e-24 84.3 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 KSA01454.1 - 2.4e-21 75.5 0.0 4e-21 74.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain DnaJ-X PF14308.6 KSA01455.1 - 9.5e-84 280.1 26.3 9.5e-84 280.1 26.3 3.7 2 2 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.31 KSA01455.1 - 6.4e-24 83.9 0.7 6.4e-24 83.9 0.7 2.5 2 0 0 2 2 2 1 DnaJ domain Fe_hyd_lg_C PF02906.14 KSA01455.1 - 0.061 13.0 5.2 0.2 11.3 5.2 1.9 1 0 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain Ribosomal_L7Ae PF01248.26 KSA01456.1 - 4.5e-23 80.8 0.4 7.6e-23 80.1 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 KSA01456.1 - 0.0012 18.9 0.1 0.0018 18.3 0.1 1.3 1 0 0 1 1 1 1 RNase P subunit Pop3 Ribosomal_L29e PF01779.17 KSA01457.1 - 3.7e-23 81.6 10.7 4.9e-23 81.2 10.7 1.2 1 0 0 1 1 1 1 Ribosomal L29e protein family RRM_1 PF00076.22 KSA01458.1 - 8.1e-06 25.6 0.0 1.7e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Transposase_24 PF03004.14 KSA01458.1 - 0.014 15.5 1.5 0.021 15.0 1.4 1.4 1 1 0 1 1 1 0 Plant transposase (Ptta/En/Spm family) YflT PF11181.8 KSA01458.1 - 0.086 13.4 1.7 0.54 10.8 1.7 2.0 1 1 0 1 1 1 0 Heat induced stress protein YflT Ribosomal_L2_C PF03947.18 KSA01459.1 - 9e-43 145.5 4.0 1.6e-42 144.6 4.0 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 KSA01459.1 - 1.8e-14 53.5 0.1 4.3e-14 52.2 0.1 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Arf PF00025.21 KSA01461.1 - 2.8e-39 134.4 0.2 3.5e-31 108.0 0.1 2.0 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 KSA01461.1 - 2e-11 44.2 0.5 2.4e-09 37.5 0.5 2.4 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 KSA01461.1 - 1e-10 41.4 0.6 0.00013 21.3 0.2 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 KSA01461.1 - 7.3e-10 38.7 0.0 3.9e-09 36.3 0.0 1.9 2 0 0 2 2 2 1 Ras family SRPRB PF09439.10 KSA01461.1 - 7.7e-09 35.2 0.0 6.9e-08 32.1 0.0 2.0 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KSA01461.1 - 8e-07 28.6 0.1 4.5e-06 26.2 0.1 1.9 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KSA01461.1 - 1.1e-06 28.7 0.0 1.7e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KSA01461.1 - 0.0001 21.9 0.0 0.00024 20.7 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 KSA01461.1 - 0.028 14.7 0.0 0.047 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain BAR_2 PF10455.9 KSA01462.1 - 2.2e-81 273.2 8.9 2.7e-81 272.9 8.9 1.1 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 KSA01462.1 - 3e-10 40.2 3.5 3e-10 40.2 3.5 2.0 2 1 0 2 2 2 1 BAR domain DUF2783 PF10932.8 KSA01462.1 - 0.12 12.0 1.7 0.28 10.9 0.5 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2783) DUF16 PF01519.16 KSA01462.1 - 0.73 10.3 5.5 15 6.1 0.2 2.9 2 1 1 3 3 3 0 Protein of unknown function DUF16 PRP38 PF03371.15 KSA01463.1 - 1.6e-46 158.4 1.0 1.8e-46 158.2 1.0 1.0 1 0 0 1 1 1 1 PRP38 family EamA PF00892.20 KSA01464.1 - 1.6e-06 28.4 48.4 0.00064 19.9 7.3 3.7 3 2 0 3 3 3 2 EamA-like transporter family CSG2 PF16965.5 KSA01464.1 - 6e-05 22.2 23.5 0.00062 18.8 23.5 2.5 1 1 0 1 1 1 1 Ceramide synthase regulator Nas2_N PF18265.1 KSA01465.1 - 2.8e-22 78.4 0.1 4.5e-22 77.7 0.1 1.4 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ PF00595.24 KSA01465.1 - 2.2e-09 37.5 0.1 3.5e-09 36.9 0.1 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KSA01465.1 - 4.6e-09 36.5 0.1 8.2e-09 35.7 0.1 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KSA01465.1 - 1.2e-07 31.5 0.1 1.8e-07 30.9 0.1 1.3 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 KSA01465.1 - 0.00019 21.8 0.0 0.00031 21.1 0.0 1.3 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain Urm1 PF09138.11 KSA01466.1 - 1.2e-34 118.5 0.0 1.4e-34 118.4 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) DDOST_48kD PF03345.14 KSA01467.1 - 4.5e-120 401.3 4.0 3e-119 398.6 4.0 1.8 1 1 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta Prefoldin_2 PF01920.20 KSA01468.1 - 3.3e-18 65.6 6.0 4.8e-18 65.1 6.0 1.2 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.17 KSA01468.1 - 0.00012 22.0 11.4 0.0018 18.2 11.2 2.1 1 1 0 1 1 1 1 Prefoldin subunit DASH_Spc34 PF08657.10 KSA01468.1 - 0.00056 19.8 3.9 0.00069 19.5 3.9 1.1 1 0 0 1 1 1 1 DASH complex subunit Spc34 Seryl_tRNA_N PF02403.22 KSA01468.1 - 0.0087 16.3 7.3 0.57 10.4 1.7 2.1 2 0 0 2 2 2 2 Seryl-tRNA synthetase N-terminal domain Med4 PF10018.9 KSA01468.1 - 0.014 15.1 9.5 0.2 11.3 2.2 2.0 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF4795 PF16043.5 KSA01468.1 - 0.016 14.8 7.3 0.022 14.4 7.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) TMF_TATA_bd PF12325.8 KSA01468.1 - 0.019 15.2 7.8 0.21 11.8 1.5 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Synaptobrevin PF00957.21 KSA01468.1 - 0.023 14.5 7.8 0.15 11.9 0.5 2.2 2 0 0 2 2 2 0 Synaptobrevin BRE1 PF08647.11 KSA01468.1 - 0.034 14.2 12.6 0.39 10.8 1.8 2.2 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF4140 PF13600.6 KSA01468.1 - 0.04 14.3 4.7 3.4 8.2 2.7 2.1 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) CENP-F_leu_zip PF10473.9 KSA01468.1 - 0.041 13.9 9.8 0.94 9.5 1.2 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4200 PF13863.6 KSA01468.1 - 0.045 14.2 11.7 0.12 12.8 3.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Baculo_PEP_C PF04513.12 KSA01468.1 - 0.047 13.7 4.2 0.085 12.9 0.7 2.0 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus GCN5L1 PF06320.13 KSA01468.1 - 0.052 13.7 8.0 0.29 11.3 0.2 2.1 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) CK2S PF15011.6 KSA01468.1 - 0.055 13.4 3.8 0.11 12.3 3.8 1.5 1 1 0 1 1 1 0 Casein Kinase 2 substrate Cep57_CLD_2 PF14197.6 KSA01468.1 - 0.065 13.3 5.5 0.78 9.9 0.2 2.6 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 LCIB_C_CA PF18599.1 KSA01468.1 - 0.075 12.3 3.5 0.16 11.2 3.7 1.6 1 1 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases FTA4 PF13093.6 KSA01468.1 - 0.076 12.9 5.7 0.14 12.1 5.7 1.4 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DivIC PF04977.15 KSA01468.1 - 0.08 12.7 9.7 2.8 7.8 5.5 2.1 2 0 0 2 2 2 0 Septum formation initiator DUF4164 PF13747.6 KSA01468.1 - 0.083 13.2 2.4 1.2 9.4 0.3 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) DUF1644 PF07800.12 KSA01468.1 - 0.085 12.9 0.7 0.11 12.6 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1644) GrpE PF01025.19 KSA01468.1 - 0.095 12.4 9.0 1.4 8.5 3.3 2.0 2 0 0 2 2 2 0 GrpE Fungal_TACC PF12709.7 KSA01468.1 - 0.12 12.8 10.8 0.09 13.2 2.1 2.2 2 0 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins DUF2968 PF11180.8 KSA01468.1 - 0.13 11.9 14.6 0.2 11.3 9.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) TPR_MLP1_2 PF07926.12 KSA01468.1 - 0.14 12.3 15.8 0.79 9.8 1.6 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF3450 PF11932.8 KSA01468.1 - 0.17 11.2 10.9 0.036 13.4 4.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) SlyX PF04102.12 KSA01468.1 - 0.19 12.4 9.5 0.2 12.3 4.1 2.1 2 0 0 2 2 2 0 SlyX DUF2203 PF09969.9 KSA01468.1 - 0.2 12.4 4.2 0.53 11.0 0.7 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF5082 PF16888.5 KSA01468.1 - 0.22 11.8 10.9 0.66 10.3 3.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) FliD_N PF02465.18 KSA01468.1 - 0.25 12.1 7.7 0.11 13.2 3.0 2.0 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF1640 PF07798.11 KSA01468.1 - 0.25 11.4 9.1 2 8.4 1.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) APG6_N PF17675.1 KSA01468.1 - 0.27 11.8 12.2 2.8 8.5 0.6 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region ATG16 PF08614.11 KSA01468.1 - 0.32 11.2 14.7 1 9.6 2.2 2.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Acetyltransf_11 PF13720.6 KSA01468.1 - 0.32 11.5 2.3 1 9.9 0.4 2.0 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 NPV_P10 PF05531.12 KSA01468.1 - 0.48 10.9 7.5 2.4 8.7 7.5 2.0 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein HMG_box PF00505.19 KSA01468.1 - 0.56 10.7 6.1 0.34 11.4 0.7 2.2 2 0 0 2 2 2 0 HMG (high mobility group) box Rootletin PF15035.6 KSA01468.1 - 0.57 10.2 11.8 1.4 8.9 11.9 1.6 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF5320 PF17253.2 KSA01468.1 - 0.63 11.1 5.6 14 6.8 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5320) V_ATPase_I PF01496.19 KSA01468.1 - 1 7.2 7.2 1.6 6.5 7.2 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family ZapB PF06005.12 KSA01468.1 - 1 9.8 13.0 4.4 7.8 1.7 2.2 2 0 0 2 2 2 0 Cell division protein ZapB Swi5 PF07061.11 KSA01468.1 - 1.1 9.4 10.2 2.8 8.1 2.5 2.4 2 0 0 2 2 2 0 Swi5 CLZ PF16526.5 KSA01468.1 - 1.2 9.6 9.0 0.51 10.7 1.9 2.1 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels USP8_interact PF08941.10 KSA01468.1 - 1.4 8.7 9.2 1.6 8.5 2.0 2.0 2 0 0 2 2 2 0 USP8 interacting Spc24 PF08286.11 KSA01468.1 - 1.9 8.8 12.8 0.7 10.2 2.9 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF4094 PF13334.6 KSA01468.1 - 2.3 8.7 6.0 1.6 9.2 2.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) UPF0242 PF06785.11 KSA01468.1 - 2.7 8.0 12.0 6 6.9 12.0 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus MAD PF05557.13 KSA01468.1 - 3 6.1 15.1 15 3.8 15.1 1.7 1 1 0 1 1 1 0 Mitotic checkpoint protein DUF4407 PF14362.6 KSA01468.1 - 3.2 7.0 11.7 13 5.0 11.7 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) LMBR1 PF04791.16 KSA01468.1 - 3.9 6.3 4.7 5 5.9 4.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4446 PF14584.6 KSA01468.1 - 5.7 6.9 9.8 3.3 7.7 1.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) ARD PF03079.14 KSA01469.1 - 7.6e-39 133.4 2.8 9.2e-39 133.1 2.8 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 KSA01469.1 - 1.6e-08 34.2 0.0 3.1e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 KSA01469.1 - 8.1e-06 25.8 0.0 1.2e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 KSA01469.1 - 0.0044 16.6 0.0 0.007 16.0 0.0 1.3 1 0 0 1 1 1 1 Cupin WD40 PF00400.32 KSA01470.1 - 1.2e-21 76.5 11.2 2.9e-07 31.1 0.3 4.5 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KSA01470.1 - 1.2e-08 35.1 1.0 0.24 11.7 0.0 4.1 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KSA01470.1 - 1.4e-05 24.6 0.0 0.00037 19.9 0.1 2.0 2 0 0 2 2 2 1 WD40-like domain eIF2A PF08662.11 KSA01470.1 - 1.5e-05 25.0 1.7 0.018 15.0 0.1 2.6 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KSA01470.1 - 0.0061 15.6 0.1 0.81 8.6 0.0 2.9 1 1 2 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein NTF2 PF02136.20 KSA01470.1 - 0.014 16.0 0.0 0.03 14.9 0.0 1.6 1 0 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain VID27 PF08553.10 KSA01470.1 - 0.066 12.3 0.0 0.19 10.7 0.0 1.9 1 1 1 2 2 2 0 VID27 C-terminal WD40-like domain WD40 PF00400.32 KSA01471.1 - 5.9e-06 26.9 0.1 0.002 18.9 0.0 2.5 2 0 0 2 2 2 2 WD domain, G-beta repeat 6PF2K PF01591.18 KSA01472.1 - 4.4e-47 160.3 8.5 6.4e-47 159.7 8.5 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase AAA_33 PF13671.6 KSA01472.1 - 2.5e-07 30.9 0.0 4.3e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 KSA01472.1 - 1.8e-06 27.7 0.0 2.8e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_18 PF13238.6 KSA01472.1 - 6.4e-05 23.5 0.0 0.00013 22.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.20 KSA01472.1 - 0.0011 18.9 0.1 0.0032 17.4 0.0 1.8 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_17 PF13207.6 KSA01472.1 - 0.0078 16.6 0.0 0.017 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 KSA01472.1 - 0.026 14.6 0.1 0.084 13.0 0.1 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_14 PF13173.6 KSA01472.1 - 0.027 14.5 0.5 0.52 10.3 0.1 2.6 1 1 1 2 2 2 0 AAA domain ADK PF00406.22 KSA01472.1 - 0.04 14.0 0.2 0.11 12.7 0.2 1.7 1 1 0 1 1 1 0 Adenylate kinase AAA_22 PF13401.6 KSA01472.1 - 0.042 14.1 0.0 0.085 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KSA01472.1 - 0.06 12.5 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Ploopntkinase3 PF18751.1 KSA01472.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 ABC_tran PF00005.27 KSA01472.1 - 0.12 12.9 1.4 0.17 12.4 0.5 1.9 2 1 0 2 2 2 0 ABC transporter Pet127 PF08634.10 KSA01473.1 - 3.1e-108 361.4 3.6 6.5e-108 360.3 3.6 1.6 1 0 0 1 1 1 1 Mitochondrial protein Pet127 CNOT1_TTP_bind PF16417.5 KSA01473.1 - 0.028 13.6 2.5 1.8 7.7 0.0 3.8 2 2 2 4 4 4 0 CCR4-NOT transcription complex subunit 1 TTP binding domain CcmF_C PF16327.5 KSA01473.1 - 0.06 12.6 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Cytochrome c-type biogenesis protein CcmF C-terminal Hap4_Hap_bind PF10297.9 KSA01474.1 - 9e-09 35.2 7.3 1.8e-08 34.2 7.3 1.5 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.21 KSA01474.1 - 3.7e-05 23.7 16.7 0.0024 17.9 8.9 3.1 1 1 1 2 2 2 2 bZIP transcription factor dsrm PF00035.26 KSA01474.1 - 0.038 14.7 0.1 0.19 12.5 0.0 2.2 2 0 0 2 2 2 0 Double-stranded RNA binding motif bZIP_2 PF07716.15 KSA01474.1 - 0.072 13.2 20.3 0.33 11.1 9.7 3.5 2 1 1 3 3 3 0 Basic region leucine zipper TMCO5 PF14992.6 KSA01474.1 - 0.086 12.4 2.6 0.2 11.2 2.6 1.6 1 0 0 1 1 1 0 TMCO5 family DUF4758 PF15950.5 KSA01474.1 - 0.47 10.8 7.9 0.73 10.2 0.0 3.2 3 0 0 3 3 3 0 Putative sperm flagellar membrane protein NIF PF03031.18 KSA01475.1 - 2.5e-42 144.3 0.1 1.3e-41 141.9 0.0 2.0 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase PBC PF03792.13 KSA01475.1 - 8.6 6.1 8.3 0.16 11.7 0.9 1.9 3 0 0 3 3 3 0 PBC domain CDP-OH_P_transf PF01066.21 KSA01476.1 - 2.4e-11 44.2 0.6 2.4e-11 44.2 0.6 2.0 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase PH PF00169.29 KSA01477.1 - 4e-05 24.1 3.8 8.1e-05 23.1 1.4 2.8 3 0 0 3 3 3 1 PH domain PH_11 PF15413.6 KSA01477.1 - 0.078 13.4 4.4 0.15 12.5 0.1 3.5 2 1 0 3 3 3 0 Pleckstrin homology domain DUF3461 PF11944.8 KSA01477.1 - 0.25 11.5 14.3 0.66 10.1 0.7 4.3 4 0 0 4 4 4 0 Protein of unknown function (DUF3461) DNA_binding_1 PF01035.20 KSA01479.1 - 1.5e-22 79.5 0.0 2.7e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain WND PF07861.11 KSA01479.1 - 0.014 14.9 1.3 0.074 12.5 1.3 1.9 1 1 0 1 1 1 0 WisP family N-Terminal Region PAPS_reduct PF01507.19 KSA01480.1 - 1.9e-43 148.5 0.0 2.5e-43 148.1 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Ceramidase PF05875.12 KSA01481.1 - 3.8e-98 328.1 12.3 4.5e-98 327.9 12.3 1.0 1 0 0 1 1 1 1 Ceramidase 7TMR-DISM_7TM PF07695.11 KSA01481.1 - 2e-05 24.6 13.0 0.0046 16.9 5.5 2.2 1 1 1 2 2 2 2 7TM diverse intracellular signalling DUF3098 PF11297.8 KSA01481.1 - 0.021 14.4 1.2 2.1 8.0 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3098) DUF4131 PF13567.6 KSA01481.1 - 0.34 10.6 5.8 2.6 7.6 0.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) MAPEG PF01124.18 KSA01481.1 - 2.9 7.8 8.1 9.8 6.1 1.5 2.4 2 0 0 2 2 2 0 MAPEG family MerC PF03203.14 KSA01481.1 - 3.3 8.2 9.4 2.4e+02 2.2 9.4 2.4 1 1 0 1 1 1 0 MerC mercury resistance protein MutS_V PF00488.21 KSA01482.1 - 8.4e-78 260.7 0.4 2.1e-77 259.4 0.1 1.8 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 KSA01482.1 - 2.5e-31 109.4 4.3 2.5e-31 109.4 4.3 1.8 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 KSA01482.1 - 8.3e-20 70.9 0.9 2.8e-19 69.2 0.9 2.0 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 KSA01482.1 - 3e-09 37.3 0.5 3e-09 37.3 0.5 3.2 3 1 0 3 3 3 1 MutS domain II MutS_I PF01624.20 KSA01482.1 - 9.1e-07 29.1 0.3 1.7e-05 25.1 0.1 2.7 3 0 0 3 3 3 1 MutS domain I DUF3759 PF12585.8 KSA01483.1 - 3.2e-41 139.2 5.9 4e-41 139.0 5.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) SAICAR_synt PF01259.18 KSA01484.1 - 2.8e-101 338.4 0.2 3.4e-101 338.1 0.2 1.0 1 0 0 1 1 1 1 SAICAR synthetase DUF4469 PF14734.6 KSA01484.1 - 0.057 13.6 0.1 11 6.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4469) with IG-like fold AICARFT_IMPCHas PF01808.18 KSA01484.1 - 0.072 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 AICARFT/IMPCHase bienzyme Pkinase PF00069.25 KSA01485.1 - 2.1e-57 194.5 0.7 1.1e-35 123.2 0.0 3.1 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 KSA01485.1 - 3.3e-36 124.9 0.0 3.3e-36 124.9 0.0 2.8 2 1 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KSA01485.1 - 2.1e-05 23.5 5.2 9e-05 21.4 0.0 2.9 3 0 0 3 3 3 1 Fungal protein kinase APH PF01636.23 KSA01485.1 - 0.013 15.4 0.4 0.38 10.6 0.0 2.6 2 1 0 3 3 3 0 Phosphotransferase enzyme family Androgen_recep PF02166.16 KSA01485.1 - 3.2 6.5 7.8 4.6 6.0 7.8 1.1 1 0 0 1 1 1 0 Androgen receptor Hydin_ADK PF17213.3 KSA01485.1 - 7 6.9 7.1 9.3 6.5 5.8 1.8 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain NAD_binding_6 PF08030.12 KSA01486.1 - 3.1e-23 82.6 0.1 4.2e-23 82.2 0.1 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KSA01486.1 - 3.8e-18 65.5 0.0 9.2e-18 64.3 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain Gb3_synth PF04572.12 KSA01486.1 - 0.036 14.3 0.1 0.067 13.4 0.1 1.4 1 0 0 1 1 1 0 Alpha 1,4-glycosyltransferase conserved region Aldo_ket_red PF00248.21 KSA01487.1 - 3.3e-22 79.0 0.0 3.2e-20 72.5 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Fungal_trans PF04082.18 KSA01488.1 - 6.6e-70 235.2 4.5 1.3e-69 234.2 4.5 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KSA01488.1 - 3.5e-06 27.2 6.0 0.00098 19.5 0.8 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KSA01488.1 - 0.003 18.3 4.2 0.18 12.7 0.4 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KSA01488.1 - 0.047 14.1 3.4 0.78 10.3 1.2 2.8 2 0 0 2 2 2 0 Zinc-finger double domain DUF2264 PF10022.9 KSA01489.1 - 1.8e-122 408.8 0.1 2.3e-122 408.5 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) Sugar_tr PF00083.24 KSA01490.1 - 3.4e-102 342.6 28.9 4e-102 342.4 28.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KSA01490.1 - 2.1e-18 66.4 32.2 3.4e-18 65.7 27.4 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Phage_holin_3_2 PF04550.12 KSA01490.1 - 0.095 13.2 4.1 0.14 12.7 1.0 2.7 2 1 1 3 3 3 0 Phage holin family 2 Sugar_tr PF00083.24 KSA01491.1 - 3.3e-84 283.3 16.6 3.8e-84 283.1 16.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KSA01491.1 - 9.2e-28 97.2 37.8 5e-26 91.5 22.7 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KSA01491.1 - 8.1e-10 37.8 13.3 5.6e-05 21.9 2.1 2.5 2 0 0 2 2 2 2 MFS/sugar transport protein MFS_4 PF06779.14 KSA01491.1 - 3.7e-06 26.5 4.0 3.7e-06 26.5 4.0 2.4 2 1 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 KSA01491.1 - 0.00041 19.3 4.9 0.00041 19.3 4.9 2.2 2 0 0 2 2 2 2 MFS_1 like family UPF0061 PF02696.14 KSA01492.1 - 1.3e-121 406.6 0.3 1.8e-121 406.2 0.3 1.1 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family Shikimate_dh_N PF08501.11 KSA01493.1 - 8.2e-19 67.6 0.0 3.9e-18 65.5 0.0 2.1 2 0 0 2 2 2 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 KSA01493.1 - 0.032 14.0 0.2 0.069 12.9 0.2 1.6 1 0 0 1 1 1 0 Shikimate 5'-dehydrogenase C-terminal domain Mannosyl_trans3 PF11051.8 KSA01494.1 - 5.6e-81 271.9 0.2 8.1e-81 271.4 0.2 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative MFS_1 PF07690.16 KSA01495.1 - 6.9e-36 123.9 67.3 1.1e-28 100.2 45.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Ost5 PF05251.12 KSA01495.1 - 0.43 10.9 0.1 0.43 10.9 0.1 5.3 5 0 0 5 5 5 0 Oligosaccharyltransferase subunit 5 Sugar_tr PF00083.24 KSA01495.1 - 7.4 5.3 36.8 0.0079 15.1 9.9 3.2 3 0 0 3 3 3 0 Sugar (and other) transporter CN_hydrolase PF00795.22 KSA01496.1 - 2.7e-54 184.2 0.0 3.1e-54 184.0 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase YoaP PF14268.6 KSA01496.1 - 0.17 11.4 0.3 0.38 10.3 0.3 1.5 1 0 0 1 1 1 0 YoaP-like Abhydrolase_1 PF00561.20 KSA01497.1 - 1.3e-24 87.2 0.0 1.8e-24 86.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KSA01497.1 - 1.4e-12 48.7 0.0 1.9e-12 48.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KSA01497.1 - 1.4e-10 40.9 0.0 2.1e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 KSA01497.1 - 0.006 16.3 0.0 0.0092 15.7 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 KSA01497.1 - 0.015 14.8 0.0 0.047 13.2 0.0 1.9 2 1 1 3 3 3 0 Prolyl oligopeptidase family PGAP1 PF07819.13 KSA01497.1 - 0.043 13.5 0.1 2.9 7.5 0.1 2.2 1 1 1 2 2 2 0 PGAP1-like protein Chlorophyllase2 PF12740.7 KSA01497.1 - 0.083 11.8 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme ABC2_membrane PF01061.24 KSA01498.1 - 4.7e-31 107.8 25.7 7.5e-31 107.2 25.7 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 KSA01498.1 - 6.6e-25 88.2 0.3 6.6e-25 88.2 0.3 1.5 2 0 0 2 2 1 1 ABC transporter AAA_22 PF13401.6 KSA01498.1 - 4e-06 27.1 0.0 1.3e-05 25.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.6 KSA01498.1 - 8.1e-05 22.6 3.0 0.25 11.1 0.1 2.9 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KSA01498.1 - 0.00039 20.4 2.0 0.00057 19.8 0.0 2.1 3 0 0 3 3 3 1 RsgA GTPase AAA_16 PF13191.6 KSA01498.1 - 0.00068 20.1 0.0 0.0014 19.1 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 KSA01498.1 - 0.0015 19.1 0.0 0.0046 17.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 KSA01498.1 - 0.0026 17.4 0.6 0.0062 16.2 0.0 1.8 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 KSA01498.1 - 0.0046 17.2 0.0 0.0088 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KSA01498.1 - 0.0064 16.2 0.1 0.015 15.0 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Roc PF08477.13 KSA01498.1 - 0.009 16.2 0.2 0.023 14.9 0.0 1.7 2 0 0 2 2 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_25 PF13481.6 KSA01498.1 - 0.011 15.3 0.0 0.023 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 KSA01498.1 - 0.013 15.0 0.5 0.054 12.9 0.5 2.0 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KSA01498.1 - 0.013 15.5 0.1 0.032 14.3 0.1 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Rad17 PF03215.15 KSA01498.1 - 0.014 15.3 0.4 0.077 12.9 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain NB-ARC PF00931.22 KSA01498.1 - 0.017 14.3 0.1 0.04 13.1 0.0 1.6 2 0 0 2 2 1 0 NB-ARC domain AAA PF00004.29 KSA01498.1 - 0.018 15.5 0.5 0.31 11.5 0.1 2.6 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 KSA01498.1 - 0.028 14.4 0.0 0.058 13.3 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_33 PF13671.6 KSA01498.1 - 0.032 14.4 0.0 0.067 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KSA01498.1 - 0.04 13.8 0.0 0.079 12.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_5 PF07728.14 KSA01498.1 - 0.058 13.4 0.0 0.33 11.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ABC2_membrane_3 PF12698.7 KSA01498.1 - 0.058 12.5 31.2 0.0092 15.1 26.5 1.9 1 1 0 1 1 1 0 ABC-2 family transporter protein SRPRB PF09439.10 KSA01498.1 - 0.061 12.8 0.1 0.17 11.3 0.0 1.8 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_24 PF13479.6 KSA01498.1 - 0.07 12.9 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain PDR_assoc PF08370.11 KSA01498.1 - 0.07 12.9 0.1 0.07 12.9 0.1 3.2 3 1 0 3 3 3 0 Plant PDR ABC transporter associated PduV-EutP PF10662.9 KSA01498.1 - 0.082 12.7 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation T2SSE PF00437.20 KSA01498.1 - 0.099 11.7 0.1 0.24 10.4 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_17 PF13207.6 KSA01498.1 - 0.1 13.0 0.0 0.26 11.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KSA01498.1 - 0.12 12.1 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KSA01498.1 - 0.13 11.7 0.0 0.38 10.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region SRP54 PF00448.22 KSA01498.1 - 0.16 11.6 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain PDR_CDR PF06422.12 KSA01498.1 - 2.2 8.2 5.2 2.1 8.3 0.1 2.6 2 0 0 2 2 2 0 CDR ABC transporter SH3_9 PF14604.6 KSA01499.1 - 4.5e-09 36.0 0.0 7.3e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KSA01499.1 - 1.2e-07 31.2 0.2 2.3e-07 30.3 0.2 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KSA01499.1 - 9e-07 28.5 0.0 1.8e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain AOX PF01786.17 KSA01500.1 - 4.1e-91 304.4 0.0 4.9e-91 304.1 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase Aa_trans PF01490.18 KSA01501.1 - 7e-99 331.3 24.6 8.1e-99 331.1 24.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Motile_Sperm PF00635.26 KSA01502.1 - 5.5e-24 84.1 0.0 9.9e-24 83.3 0.0 1.4 1 0 0 1 1 1 1 MSP (Major sperm protein) domain TMEM131_like PF12371.8 KSA01502.1 - 0.028 14.6 0.1 0.049 13.9 0.1 1.3 1 0 0 1 1 1 0 Transmembrane protein 131-like PapD-like PF14874.6 KSA01502.1 - 0.036 14.2 0.0 0.085 13.0 0.0 1.6 1 0 0 1 1 1 0 Flagellar-associated PapD-like Peptidase_M24 PF00557.24 KSA01503.1 - 4.3e-43 147.4 0.0 5.5e-43 147.1 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 RP-C_C PF11800.8 KSA01503.1 - 0.066 13.3 1.7 0.12 12.5 1.7 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region ALG11_N PF15924.5 KSA01505.1 - 1e-70 238.0 0.2 1.8e-70 237.2 0.2 1.4 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 KSA01505.1 - 2.7e-15 56.3 0.0 6.1e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KSA01505.1 - 0.00061 20.2 0.0 0.0012 19.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 PXB PF12828.7 KSA01505.1 - 0.83 9.6 3.1 15 5.5 0.1 2.6 3 0 0 3 3 3 0 PX-associated Coatomer_WDAD PF04053.14 KSA01506.1 - 2e-175 584.1 5.3 2e-175 584.1 5.3 1.9 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 KSA01506.1 - 1.1e-36 124.2 6.8 4.5e-07 30.4 0.0 9.0 8 1 1 9 9 9 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KSA01506.1 - 4.4e-10 39.7 0.8 2.1 8.7 0.0 6.8 3 2 4 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 KSA01506.1 - 0.00037 20.5 0.1 0.22 11.5 0.0 4.0 2 2 2 4 4 4 1 Ciliary BBSome complex subunit 2, middle region MetallophosC PF16370.5 KSA01506.1 - 0.0034 17.7 0.1 0.014 15.6 0.0 2.0 1 1 0 1 1 1 1 C terminal of Calcineurin-like phosphoesterase Nup160 PF11715.8 KSA01506.1 - 0.0045 15.7 9.1 0.045 12.4 0.0 4.7 3 1 3 6 6 6 2 Nucleoporin Nup120/160 PQQ PF01011.21 KSA01506.1 - 0.13 12.2 1.1 1.7 8.7 0.0 3.5 4 0 0 4 4 4 0 PQQ enzyme repeat Na_trans_assoc PF06512.13 KSA01506.1 - 1 9.6 13.6 1.7 8.9 13.6 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated FtsJ PF01728.19 KSA01507.1 - 5.7e-25 88.4 0.0 8.7e-25 87.9 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.6 KSA01507.1 - 0.032 14.1 0.0 0.074 12.9 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Ribosomal_L1 PF00687.21 KSA01508.1 - 3.9e-42 144.3 1.3 4.6e-42 144.1 1.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family partial_CstF PF15861.5 KSA01508.1 - 0.035 13.9 0.4 0.11 12.3 0.3 1.9 1 1 0 1 1 1 0 Partial cleavage stimulation factor domain MMR_HSR1 PF01926.23 KSA01509.1 - 1.1e-16 60.9 0.7 1e-14 54.6 0.0 2.9 3 0 0 3 3 3 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KSA01509.1 - 2.1e-07 30.6 1.0 1.2e-05 24.9 0.0 2.7 3 0 0 3 3 3 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KSA01509.1 - 1.2e-06 28.5 0.1 0.0048 16.8 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AIG1 PF04548.16 KSA01509.1 - 0.013 14.9 0.0 0.028 13.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family cobW PF02492.19 KSA01509.1 - 0.04 13.5 0.2 0.15 11.6 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.23 KSA01509.1 - 0.044 13.9 0.9 0.11 12.6 0.0 2.1 2 0 0 2 2 2 0 Dynamin family Arf PF00025.21 KSA01510.1 - 1.1e-63 213.9 0.0 1.2e-63 213.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KSA01510.1 - 1.8e-11 43.9 0.0 7.9e-08 31.8 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 KSA01510.1 - 3.5e-09 36.4 0.0 4.6e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 KSA01510.1 - 1.2e-07 31.9 0.0 3.1e-07 30.6 0.0 1.6 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KSA01510.1 - 1.3e-07 31.4 0.0 1.6e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 KSA01510.1 - 2.6e-06 27.5 0.0 3.5e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KSA01510.1 - 0.00019 20.9 0.0 0.00022 20.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KSA01510.1 - 0.048 13.2 0.0 1.1 8.7 0.0 2.0 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 KSA01510.1 - 0.14 11.9 0.0 0.49 10.1 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF1992 PF09350.10 KSA01512.1 - 2.8e-18 65.8 0.0 2.2e-17 63.0 0.0 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF1992) DUF1666 PF07891.12 KSA01512.1 - 0.051 13.2 1.3 0.084 12.5 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1666) Secretin_N_2 PF07655.13 KSA01512.1 - 2.6 8.6 5.4 0.45 11.1 1.1 1.9 2 0 0 2 2 2 0 Secretin N-terminal domain Glycos_transf_1 PF00534.20 KSA01513.1 - 4.8e-26 91.3 0.5 4.3e-13 49.1 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KSA01513.1 - 9.4e-14 51.8 0.0 1.4e-13 51.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 KSA01513.1 - 1.1e-05 25.8 0.0 2.3e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 ALG11_N PF15924.5 KSA01513.1 - 0.0072 16.4 0.3 0.17 11.9 0.3 2.5 2 1 0 2 2 2 1 ALG11 mannosyltransferase N-terminus Wyosine_form PF08608.12 KSA01514.1 - 3.4e-20 72.2 0.0 7.1e-20 71.1 0.0 1.6 1 0 0 1 1 1 1 Wyosine base formation Radical_SAM PF04055.21 KSA01514.1 - 3e-19 70.0 0.0 7.5e-19 68.7 0.0 1.7 1 0 0 1 1 1 1 Radical SAM superfamily Flavodoxin_1 PF00258.25 KSA01514.1 - 1.9e-14 54.1 0.0 4.5e-14 52.9 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin Phage_TTP_13 PF16463.5 KSA01514.1 - 0.099 12.2 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 Phage tail tube protein family DUF4451 PF14616.6 KSA01515.1 - 5.3e-33 113.8 3.2 9.9e-33 112.9 3.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) SCA7 PF08313.12 KSA01516.1 - 5.7e-30 103.0 0.2 1.9e-29 101.3 0.2 1.9 1 0 0 1 1 1 1 SCA7, zinc-binding domain Sgf11 PF08209.11 KSA01516.1 - 0.0051 16.3 0.5 0.0092 15.5 0.5 1.4 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) zf_C2H2_13 PF18508.1 KSA01516.1 - 0.031 13.9 0.4 0.031 13.9 0.4 2.0 2 0 0 2 2 2 0 Zinc finger domain Pkinase PF00069.25 KSA01517.1 - 1.8e-72 243.9 0.2 2.3e-72 243.5 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KSA01517.1 - 5.8e-46 156.9 0.0 8e-46 156.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KSA01517.1 - 3e-07 30.1 0.0 8.4e-07 28.6 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KSA01517.1 - 7.7e-06 24.9 0.1 8.8e-06 24.7 0.1 1.3 1 1 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KSA01517.1 - 0.0031 16.9 0.1 0.0052 16.2 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KSA01517.1 - 0.039 13.6 0.3 8.8 5.9 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 KSA01517.1 - 0.09 11.7 7.6 0.2 10.5 7.6 1.5 1 1 0 1 1 1 0 Haspin like kinase domain Pkinase PF00069.25 KSA01519.1 - 2.2e-25 89.5 0.7 5.4e-25 88.2 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KSA01519.1 - 7.5e-14 51.6 0.0 1.5e-13 50.6 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KSA01519.1 - 5.7e-08 32.0 0.0 5.7e-08 32.0 0.0 2.2 2 1 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KSA01519.1 - 1.9e-05 24.7 0.5 0.0031 17.5 0.0 3.0 3 0 0 3 3 3 1 Phosphotransferase enzyme family PseudoU_synth_1 PF01416.20 KSA01520.1 - 2.2e-12 47.4 0.0 1.5e-10 41.5 0.0 2.6 2 0 0 2 2 2 2 tRNA pseudouridine synthase UPF0113_N PF17833.1 KSA01521.1 - 1.2e-31 109.0 0.2 1.8e-31 108.5 0.2 1.3 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 KSA01521.1 - 3.3e-25 88.1 0.0 6.4e-25 87.2 0.0 1.5 1 0 0 1 1 1 1 UPF0113 PUA domain DAP3 PF10236.9 KSA01522.1 - 2.8e-64 217.2 0.1 5.1e-64 216.4 0.1 1.5 1 1 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.6 KSA01522.1 - 0.0043 17.4 0.0 0.01 16.2 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 KSA01522.1 - 0.0065 16.5 0.0 0.015 15.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Roc PF08477.13 KSA01522.1 - 0.055 13.7 1.0 1.1 9.5 0.1 2.7 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 KSA01522.1 - 0.06 13.2 0.1 0.15 11.9 0.0 1.7 2 0 0 2 2 2 0 RsgA GTPase AAA_22 PF13401.6 KSA01522.1 - 0.08 13.2 0.1 0.66 10.2 0.1 2.2 1 1 0 1 1 1 0 AAA domain DEAD PF00270.29 KSA01523.1 - 8.3e-25 87.5 0.0 7.1e-24 84.5 0.0 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KSA01523.1 - 8e-16 58.4 0.2 3e-15 56.5 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KSA01523.1 - 2.6e-09 37.3 0.0 1e-06 28.9 0.0 2.6 2 1 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KSA01523.1 - 0.12 12.7 0.4 5 7.4 0.1 3.4 2 1 0 2 2 2 0 AAA domain NUDIX PF00293.28 KSA01524.1 - 2.9e-11 43.5 0.0 5.6e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.11 KSA01524.1 - 2.4e-06 28.1 0.0 7.7e-06 26.5 0.0 1.9 1 1 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.11 KSA01524.1 - 2.1e-05 24.1 0.6 4.2e-05 23.1 0.6 1.5 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain DpnI PF06044.12 KSA01524.1 - 0.12 12.0 0.0 0.79 9.3 0.0 2.0 2 0 0 2 2 2 0 Dam-replacing family DZR PF12773.7 KSA01524.1 - 0.17 12.0 0.2 0.3 11.2 0.2 1.4 1 0 0 1 1 1 0 Double zinc ribbon DNA_ligase_ZBD PF03119.16 KSA01524.1 - 0.23 11.5 1.5 0.75 9.9 1.5 1.9 1 1 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain GDPD PF03009.17 KSA01525.1 - 5e-25 88.7 0.0 5.2e-24 85.4 0.0 2.2 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family SKIP_SNW PF02731.15 KSA01526.1 - 8e-57 191.4 9.0 1.6e-56 190.4 9.0 1.5 1 0 0 1 1 1 1 SKIP/SNW domain UCMA PF17085.5 KSA01526.1 - 0.13 12.3 2.7 0.82 9.7 0.1 2.3 2 0 0 2 2 2 0 Unique cartilage matrix associated protein DUF4845 PF16137.5 KSA01526.1 - 0.45 11.4 8.0 4.2 8.3 0.4 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF4845) WAC_Acf1_DNA_bd PF10537.9 KSA01527.1 - 4.9e-26 91.2 0.4 2e-25 89.3 0.4 2.2 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal WSD PF15613.6 KSA01527.1 - 2.1e-15 57.0 5.6 2.1e-15 57.0 5.6 4.8 5 2 0 5 5 5 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 KSA01527.1 - 2.2e-15 56.7 0.1 4.4e-15 55.7 0.1 1.5 1 0 0 1 1 1 1 DDT domain WHIM1 PF15612.6 KSA01527.1 - 5.8e-06 25.7 0.0 1.3e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Abi_C PF14355.6 KSA01527.1 - 0.15 12.2 0.5 0.5 10.5 0.5 1.9 1 0 0 1 1 1 0 Abortive infection C-terminus ADH_N PF08240.12 KSA01528.1 - 5.4e-24 84.2 6.0 7.1e-24 83.8 6.0 1.2 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Kelch_5 PF13854.6 KSA01529.1 - 5.2e-13 48.7 2.3 5e-06 26.4 0.0 3.5 3 1 0 3 3 3 3 Kelch motif Kelch_4 PF13418.6 KSA01529.1 - 1.3e-08 34.7 3.7 0.002 18.1 0.0 3.5 3 1 0 3 3 3 3 Galactose oxidase, central domain Kelch_3 PF13415.6 KSA01529.1 - 4.2e-07 30.1 4.2 0.012 15.8 0.2 4.2 4 1 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.15 KSA01529.1 - 0.00013 21.8 0.2 7.6 6.7 0.1 3.4 3 0 0 3 3 3 3 Kelch motif Kelch_6 PF13964.6 KSA01529.1 - 0.0003 21.0 0.9 1.8 8.9 0.0 3.2 3 0 0 3 3 3 2 Kelch motif RAG2 PF03089.14 KSA01529.1 - 0.026 13.5 0.0 0.15 11.0 0.0 2.0 2 0 0 2 2 2 0 Recombination activating protein 2 Kelch_1 PF01344.25 KSA01529.1 - 0.13 11.8 0.0 5 6.8 0.0 2.8 3 0 0 3 3 3 0 Kelch motif Toxin_TOLIP PF00087.21 KSA01530.1 - 0.09 13.0 0.2 0.18 12.0 0.2 1.5 1 0 0 1 1 1 0 Snake toxin and toxin-like protein Cnd1 PF12717.7 KSA01531.1 - 2.7e-05 24.3 5.7 3e-05 24.1 1.1 3.1 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Pkinase PF00069.25 KSA01531.1 - 2.9e-05 23.6 0.0 5.6e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KSA01531.1 - 0.00062 19.1 0.0 0.0011 18.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase FAM183 PF14886.6 KSA01531.1 - 0.011 16.5 0.5 0.21 12.3 0.0 2.9 3 0 0 3 3 3 0 FAM183A and FAM183B related HEAT PF02985.22 KSA01531.1 - 0.1 12.9 0.0 34 5.1 0.0 3.6 3 0 0 3 3 3 0 HEAT repeat zf-C2H2 PF00096.26 KSA01532.1 - 2.9e-19 68.4 29.1 5.6e-05 23.4 0.8 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KSA01532.1 - 4e-18 64.9 30.1 2.7e-08 33.9 0.9 4.6 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KSA01532.1 - 1.2e-11 44.4 25.6 0.0084 16.9 0.5 4.5 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KSA01532.1 - 0.00023 21.1 8.9 0.00041 20.3 2.3 4.0 4 0 0 4 4 4 2 C2H2-type zinc finger zf-met PF12874.7 KSA01532.1 - 0.00057 20.2 13.9 0.023 15.1 0.1 4.4 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-Di19 PF05605.12 KSA01532.1 - 0.0074 16.6 9.2 0.034 14.4 4.7 2.5 1 1 1 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 KSA01532.1 - 0.098 13.0 14.1 1.4 9.3 0.1 4.6 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding GAGA PF09237.11 KSA01532.1 - 1.1 9.1 5.5 1.7 8.5 0.1 3.5 2 1 2 4 4 4 0 GAGA factor zf-MYST PF17772.1 KSA01532.1 - 3.3 7.4 6.3 0.37 10.4 0.7 2.3 3 0 0 3 3 3 0 MYST family zinc finger domain DUF2256 PF10013.9 KSA01532.1 - 3.7 7.7 10.2 4.7 7.4 1.6 3.2 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) Prominin PF05478.11 KSA01532.1 - 6.1 4.7 5.6 0.43 8.5 0.0 1.7 2 0 0 2 2 2 0 Prominin SID PF11778.8 KSA01533.1 - 3.2e-07 30.5 2.7 3.2e-07 30.5 2.7 2.7 2 0 0 2 2 2 1 Septation initiation MCC-bdg_PDZ PF10506.9 KSA01533.1 - 0.024 14.7 14.9 0.042 13.9 5.2 3.9 2 1 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome WD40_alt PF14077.6 KSA01533.1 - 0.33 10.8 3.3 6.9 6.6 0.0 3.4 3 0 0 3 3 3 0 Alternative WD40 repeat motif RNA_pol_L_2 PF13656.6 KSA01534.1 - 1e-33 114.9 0.0 1.3e-33 114.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 KSA01534.1 - 5e-16 57.9 0.0 6.8e-16 57.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DEAD PF00270.29 KSA01535.1 - 4.2e-48 163.4 0.0 1.3e-47 161.8 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KSA01535.1 - 1.1e-29 103.1 0.0 2.6e-29 101.8 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KSA01535.1 - 4.1e-05 23.6 0.0 7e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KSA01535.1 - 0.001 19.4 0.0 0.63 10.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KSA01535.1 - 0.028 14.1 0.0 0.89 9.2 0.0 2.4 1 1 0 1 1 1 0 AAA domain DUF5335 PF17269.2 KSA01535.1 - 0.091 12.6 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5335) PEMT PF04191.13 KSA01536.1 - 4.6e-59 197.4 10.6 6.4e-35 119.7 1.1 3.1 2 0 0 2 2 2 2 Phospholipid methyltransferase SKICH PF17751.1 KSA01536.1 - 1.4e-05 25.6 0.2 3.6e-05 24.3 0.2 1.7 1 0 0 1 1 1 1 SKICH domain HECW_N PF16562.5 KSA01536.1 - 0.033 14.0 0.1 0.11 12.3 0.1 1.9 1 0 0 1 1 1 0 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 YpmT PF17431.2 KSA01536.1 - 0.24 11.4 4.5 1.1 9.4 4.5 2.1 1 0 0 1 1 1 0 Uncharacterized YmpT-like Steroid_dh PF02544.16 KSA01536.1 - 1.4 8.9 16.8 0.28 11.2 6.1 3.1 2 2 0 2 2 2 0 3-oxo-5-alpha-steroid 4-dehydrogenase RNase_PH PF01138.21 KSA01537.1 - 9.7e-35 119.9 0.0 1.5e-34 119.4 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 S4_2 PF13275.6 KSA01537.1 - 0.14 12.0 0.1 0.47 10.3 0.0 1.9 2 0 0 2 2 2 0 S4 domain Fungal_trans PF04082.18 KSA01538.1 - 2.7e-33 115.1 2.9 2.7e-33 115.1 2.9 2.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KSA01538.1 - 5.1e-10 39.3 10.5 1.2e-09 38.1 10.5 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KSA01538.1 - 0.0015 17.4 0.8 0.015 14.1 0.8 2.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain YfhD PF14151.6 KSA01538.1 - 0.041 14.0 6.0 0.24 11.6 0.6 3.2 3 0 0 3 3 3 0 YfhD-like protein zf-C4pol PF14260.6 KSA01538.1 - 0.14 12.6 6.4 0.53 10.8 6.4 2.0 1 0 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta Pigment_DH PF06324.11 KSA01538.1 - 0.41 10.8 0.1 0.41 10.8 0.1 2.4 2 0 0 2 2 2 0 Pigment-dispersing hormone (PDH) GTP_cyclohydro2 PF00925.20 KSA01539.1 - 1.4e-59 200.3 0.0 2e-59 199.9 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II Thioredoxin_2 PF13098.6 KSA01540.1 - 0.00019 21.8 0.0 0.00032 21.1 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain Evr1_Alr PF04777.13 KSA01541.1 - 9.5e-31 106.2 3.9 1.1e-30 106.0 2.7 1.7 2 0 0 2 2 2 1 Erv1 / Alr family APOBEC4 PF18775.1 KSA01541.1 - 0.34 11.1 1.7 0.59 10.3 0.4 2.0 2 1 0 2 2 2 0 APOBEC4 HD_3 PF13023.6 KSA01542.1 - 3.9e-36 124.5 0.0 4.7e-36 124.2 0.0 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 KSA01542.1 - 4e-08 33.2 0.1 5.2e-08 32.9 0.1 1.2 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 KSA01542.1 - 9.8e-05 22.6 0.0 0.0002 21.6 0.0 1.4 1 0 0 1 1 1 1 HD domain Ribosomal_L27A PF00828.19 KSA01543.1 - 2.1e-22 80.2 0.1 3.3e-22 79.5 0.0 1.3 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Sugar_tr PF00083.24 KSA01544.1 - 1.9e-100 336.9 18.1 2.9e-100 336.3 18.1 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KSA01544.1 - 1e-32 113.5 34.3 1.2e-25 90.2 8.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KSA01544.1 - 8.6e-09 35.2 3.6 8.6e-09 35.2 3.6 2.3 3 0 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB TRI12 PF06609.13 KSA01544.1 - 1.8e-05 23.4 2.7 1.8e-05 23.4 2.7 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) DUF4191 PF13829.6 KSA01544.1 - 0.15 11.3 0.1 0.15 11.3 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4191) Zn_clus PF00172.18 KSA01545.1 - 3.3e-06 27.1 13.2 7.1e-06 26.0 13.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.25 KSA01545.1 - 0.0004 20.4 0.0 0.00072 19.5 0.0 1.4 1 0 0 1 1 1 1 PAS fold tRNA_bind PF01588.20 KSA01546.1 - 2.6e-26 91.5 0.0 6.7e-26 90.2 0.0 1.7 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C PF00043.25 KSA01546.1 - 0.11 12.8 2.3 0.15 12.3 0.0 2.4 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain RNA_pol_Rpc4 PF05132.14 KSA01546.1 - 0.39 11.1 4.4 0.9 10.0 4.4 1.7 1 0 0 1 1 1 0 RNA polymerase III RPC4 eRF1_1 PF03463.15 KSA01547.1 - 8.2e-38 129.3 0.0 1.1e-37 129.0 0.0 1.1 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.15 KSA01547.1 - 2.2e-09 37.7 0.0 3.5e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 KSA01548.1 - 3.2e-20 72.7 0.0 5.2e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_2 PF03464.15 KSA01548.1 - 3.7e-12 46.7 0.1 5.7e-12 46.1 0.1 1.3 1 0 0 1 1 1 1 eRF1 domain 2 Tim17 PF02466.19 KSA01549.1 - 0.012 15.9 1.2 0.021 15.2 1.2 1.4 1 0 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family DUF4234 PF14018.6 KSA01549.1 - 0.022 14.9 1.3 0.054 13.6 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4234) AAA_23 PF13476.6 KSA01550.1 - 1.1e-17 65.3 16.6 1.1e-17 65.3 16.6 5.7 2 2 2 4 4 1 1 AAA domain SMC_N PF02463.19 KSA01550.1 - 5.8e-15 55.3 32.5 5.3e-14 52.2 32.5 2.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 KSA01550.1 - 3.4e-09 36.9 27.0 3.4e-09 36.9 27.0 3.4 2 1 1 3 3 2 1 AAA ATPase domain AAA_29 PF13555.6 KSA01550.1 - 4.6e-05 23.1 0.0 8.9e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 KSA01550.1 - 0.0013 19.2 0.0 0.0013 19.2 0.0 5.3 3 2 0 3 3 1 1 ABC transporter AAA_21 PF13304.6 KSA01550.1 - 0.0018 18.1 0.0 0.0018 18.1 0.0 3.9 3 2 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 KSA01550.1 - 0.0096 16.1 1.6 0.12 12.5 0.0 3.4 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KSA01550.1 - 0.019 14.9 0.3 0.16 11.9 0.0 2.8 2 0 0 2 2 2 0 RsgA GTPase AAA PF00004.29 KSA01550.1 - 0.056 13.9 0.0 0.056 13.9 0.0 3.1 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KSA01550.1 - 0.085 13.3 2.7 0.15 12.4 0.1 2.9 2 0 0 2 2 2 0 RNA helicase AAA_22 PF13401.6 KSA01550.1 - 0.48 10.7 0.0 0.48 10.7 0.0 3.4 4 0 0 4 4 4 0 AAA domain tRNA-synt_1c PF00749.21 KSA01551.1 - 3.2e-101 338.3 0.0 4.2e-101 338.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain DUF4452 PF14618.6 KSA01552.1 - 0.023 14.6 4.8 0.1 12.4 4.8 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4452) PDZ_assoc PF10600.9 KSA01552.1 - 4 8.3 13.0 0.26 12.1 3.4 3.2 1 1 3 4 4 4 0 PDZ-associated domain of NMDA receptors MPM1 PF17234.2 KSA01553.1 - 2.2e-54 184.3 7.5 2.2e-54 184.3 7.5 2.0 2 0 0 2 2 2 1 Mitochondrial peculiar membrane protein 1 CLASP_N PF12348.8 KSA01553.1 - 0.052 13.1 0.0 0.094 12.3 0.0 1.3 1 0 0 1 1 1 0 CLASP N terminal SH3_13 PF18335.1 KSA01553.1 - 0.12 12.2 3.6 2.9 7.8 0.1 2.6 2 0 0 2 2 2 0 ATP-dependent RecD-like DNA helicase SH3 domain ING PF12998.7 KSA01553.1 - 2 9.0 6.1 1.8 9.2 0.1 3.0 2 1 1 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding Vps55 PF04133.14 KSA01554.1 - 1.6e-41 140.9 6.5 1.8e-41 140.8 6.5 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 Polysacc_synt PF01943.17 KSA01554.1 - 0.0014 18.1 1.2 0.0017 17.8 1.2 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Lysine_decarbox PF03641.14 KSA01555.1 - 2.7e-41 140.8 0.1 3.5e-41 140.4 0.1 1.2 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 KSA01555.1 - 4.9e-16 58.7 0.1 1.1e-15 57.6 0.1 1.6 1 1 0 1 1 1 1 SLOG cluster4 family TerB_N PF13208.6 KSA01556.1 - 0.04 13.6 0.0 0.049 13.3 0.0 1.0 1 0 0 1 1 1 0 TerB N-terminal domain SNARE PF05739.19 KSA01557.1 - 0.00052 19.9 1.3 0.001 19.0 1.3 1.5 1 0 0 1 1 1 1 SNARE domain Dynactin_p22 PF07426.11 KSA01557.1 - 0.83 9.5 7.5 0.49 10.2 2.5 2.9 2 2 1 3 3 3 0 Dynactin subunit p22 DUF2247 PF10004.9 KSA01557.1 - 1.2 8.9 6.3 0.32 10.8 2.7 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2247) Pro_CA PF00484.19 KSA01558.1 - 1.5e-41 142.3 0.0 2.1e-41 141.8 0.0 1.2 1 0 0 1 1 1 1 Carbonic anhydrase RINT1_TIP1 PF04437.13 KSA01558.1 - 0.016 14.1 0.0 0.023 13.6 0.0 1.2 1 0 0 1 1 1 0 RINT-1 / TIP-1 family DUF4381 PF14316.6 KSA01558.1 - 0.18 12.1 0.0 0.3 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) SNF2_N PF00176.23 KSA01559.1 - 1.7e-66 224.4 0.4 3.8e-66 223.2 0.4 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KSA01559.1 - 7.1e-21 74.6 0.1 2.3e-20 73.0 0.1 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 KSA01559.1 - 6.9e-10 38.6 3.0 1.4e-09 37.6 1.9 2.0 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 KSA01559.1 - 7.8e-08 32.5 0.0 7.8e-08 32.5 0.0 2.6 3 1 1 4 4 4 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KSA01559.1 - 6.9e-07 29.2 0.0 1.5e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 KSA01559.1 - 0.0049 16.1 1.5 0.009 15.2 1.5 1.6 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Glyco_hydro_15 PF00723.21 KSA01560.1 - 4.6e-63 213.6 0.0 5.6e-63 213.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 MMgT PF10270.9 KSA01561.1 - 3e-27 94.9 0.1 3.4e-27 94.7 0.1 1.0 1 0 0 1 1 1 1 Membrane magnesium transporter YrhK PF14145.6 KSA01561.1 - 0.02 14.7 0.7 0.092 12.6 0.7 1.9 1 1 0 1 1 1 0 YrhK-like protein RIFIN PF02009.16 KSA01561.1 - 0.032 14.1 1.2 0.053 13.4 1.2 1.3 1 0 0 1 1 1 0 Rifin DUF2577 PF10844.8 KSA01561.1 - 0.11 12.7 0.0 0.15 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2577) FA_hydroxylase PF04116.13 KSA01562.1 - 9.1e-25 87.5 25.0 9.1e-25 87.5 25.0 1.7 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily SID PF11778.8 KSA01562.1 - 0.029 14.5 0.0 0.049 13.7 0.0 1.4 1 0 0 1 1 1 0 Septation initiation MFS_1 PF07690.16 KSA01563.1 - 2.6e-39 135.1 26.7 2.6e-39 135.1 26.7 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 KSA01563.1 - 8.7e-06 25.3 2.4 8.7e-06 25.3 2.4 2.9 3 0 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB BT1 PF03092.16 KSA01563.1 - 0.016 13.5 1.5 0.028 12.7 1.5 1.3 1 0 0 1 1 1 0 BT1 family BtrH_N PF14399.6 KSA01563.1 - 0.074 13.3 0.4 0.18 12.0 0.1 1.7 2 0 0 2 2 2 0 Butirosin biosynthesis protein H, N-terminal Cyd_oper_YbgE PF09600.10 KSA01563.1 - 7.1 7.1 13.0 20 5.6 0.4 2.8 2 0 0 2 2 2 0 Cyd operon protein YbgE (Cyd_oper_YbgE) adh_short_C2 PF13561.6 KSA01564.1 - 3.4e-51 174.0 0.1 6.8e-51 173.1 0.1 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KSA01564.1 - 4.4e-39 134.0 0.1 8.4e-39 133.0 0.1 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KSA01564.1 - 1.8e-06 28.0 0.0 2.6e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 KR domain NmrA PF05368.13 KSA01564.1 - 0.055 13.0 0.1 0.13 11.8 0.0 1.7 2 0 0 2 2 2 0 NmrA-like family Gtr1_RagA PF04670.12 KSA01565.1 - 1.3e-67 227.6 0.8 2.1e-67 226.9 0.8 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 KSA01565.1 - 0.0081 15.6 0.0 0.02 14.3 0.0 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family AAA_14 PF13173.6 KSA01565.1 - 0.011 15.8 0.1 0.062 13.3 0.0 2.3 2 1 0 2 2 2 0 AAA domain tRNA-synt_2 PF00152.20 KSA01566.1 - 1e-79 267.9 0.2 1.7e-79 267.2 0.2 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KSA01566.1 - 2.3e-05 24.3 0.6 4.2e-05 23.4 0.6 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain FAM178 PF14816.6 KSA01566.1 - 0.011 14.7 1.7 0.018 14.1 1.7 1.2 1 0 0 1 1 1 0 Family of unknown function, FAM178 ATP-synt_B PF00430.18 KSA01566.1 - 0.16 12.0 7.6 0.67 10.0 7.6 2.0 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) TYW3 PF02676.14 KSA01567.1 - 8.9e-68 227.8 0.0 1.4e-67 227.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase TYW3 CHD5 PF04420.14 KSA01567.1 - 3 7.7 6.3 5 6.9 6.3 1.3 1 0 0 1 1 1 0 CHD5-like protein NatB_MDM20 PF09797.9 KSA01568.1 - 9.1e-64 215.8 24.7 9.1e-64 215.8 24.7 1.8 2 0 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_19 PF14559.6 KSA01568.1 - 0.033 14.7 0.0 0.32 11.5 0.0 2.5 1 1 0 2 2 2 0 Tetratricopeptide repeat Popeye PF04831.13 KSA01568.1 - 0.079 13.1 0.1 0.079 13.1 0.1 2.2 3 0 0 3 3 3 0 Popeye protein conserved region TPR_2 PF07719.17 KSA01568.1 - 0.091 12.9 0.1 26 5.2 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Complex1_LYR PF05347.15 KSA01569.1 - 0.00053 20.0 1.3 0.00085 19.3 1.3 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) TetR_C_3 PF08362.11 KSA01570.1 - 0.084 12.8 0.0 3.9 7.4 0.0 2.6 3 0 0 3 3 3 0 YcdC-like protein, C-terminal region LRR_4 PF12799.7 KSA01571.1 - 3.7e-05 24.0 11.5 0.35 11.4 4.0 4.4 2 1 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KSA01571.1 - 0.0011 18.9 6.1 0.3 11.3 0.0 4.7 6 0 0 6 6 6 2 Leucine Rich repeat Arrestin_C PF02752.22 KSA01572.1 - 4.8e-23 82.1 0.7 3e-22 79.5 0.1 2.4 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KSA01572.1 - 3e-09 37.1 0.0 3.8e-08 33.5 0.0 2.3 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 KSA01572.1 - 0.002 17.8 0.0 0.0051 16.5 0.0 1.6 1 0 0 1 1 1 1 Arrestin_N terminal like SNARE PF05739.19 KSA01573.1 - 4.5e-11 42.6 1.8 4.8e-11 42.5 0.3 1.9 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 KSA01573.1 - 0.048 13.3 13.6 0.2 11.3 13.6 2.1 1 1 0 1 1 1 0 Syntaxin Ribosomal_S6 PF01250.17 KSA01573.1 - 0.12 12.6 2.2 0.59 10.4 0.4 2.7 2 1 1 3 3 3 0 Ribosomal protein S6 SprA-related PF12118.8 KSA01573.1 - 0.18 10.9 2.4 0.33 10.1 2.4 1.3 1 0 0 1 1 1 0 SprA-related family SUR7 PF06687.12 KSA01574.1 - 7.1e-20 71.5 23.9 1.1e-19 70.9 23.9 1.2 1 0 0 1 1 1 1 SUR7/PalI family PIP5K PF01504.18 KSA01575.1 - 2e-41 142.0 5.0 2e-33 115.8 4.8 4.5 3 2 1 4 4 4 2 Phosphatidylinositol-4-phosphate 5-Kinase TF_AP-2 PF03299.14 KSA01575.1 - 0.73 9.8 7.2 0.14 12.1 2.5 2.2 2 0 0 2 2 2 0 Transcription factor AP-2 Cpn60_TCP1 PF00118.24 KSA01576.1 - 3.2e-18 65.6 0.7 5.7e-18 64.8 0.7 1.3 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 KSA01576.1 - 2.6e-16 59.5 10.4 5.7e-16 58.4 10.4 1.5 1 0 0 1 1 1 1 FYVE zinc finger A2L_zn_ribbon PF08792.10 KSA01576.1 - 0.48 10.2 3.7 0.2 11.4 0.3 2.2 2 0 0 2 2 2 0 A2L zinc ribbon domain C1_4 PF07975.12 KSA01576.1 - 3.4 8.0 9.8 6.4 7.1 8.3 2.3 2 0 0 2 2 2 0 TFIIH C1-like domain GPP34 PF05719.11 KSA01577.1 - 1.3e-66 224.6 0.0 1.5e-66 224.3 0.0 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) Glyco_hydro_18 PF00704.28 KSA01578.1 - 1.2e-78 265.0 0.4 1.4e-78 264.8 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 UCH PF00443.29 KSA01579.1 - 1e-43 149.7 0.3 1.9e-43 148.8 0.3 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KSA01579.1 - 4e-23 81.5 20.1 4.5e-20 71.7 9.2 3.5 3 0 0 3 3 3 2 Zn-finger in ubiquitin-hydrolases and other protein zf-UBP_var PF17807.1 KSA01579.1 - 7.8e-22 76.8 7.0 1.4e-20 72.8 1.8 2.9 2 0 0 2 2 2 2 Variant UBP zinc finger UBA PF00627.31 KSA01579.1 - 1.3e-21 76.1 0.0 5.8e-11 42.1 0.0 3.0 3 0 0 3 3 3 2 UBA/TS-N domain UCH_1 PF13423.6 KSA01579.1 - 1.5e-13 51.0 10.5 6.8e-13 48.9 1.8 3.4 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DAHP_synth_1 PF00793.20 KSA01580.1 - 9.2e-102 339.6 0.0 1.1e-101 339.3 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family SNF2_N PF00176.23 KSA01581.1 - 1.9e-66 224.2 0.1 3.4e-66 223.3 0.1 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 KSA01581.1 - 7.6e-16 57.8 0.0 2e-15 56.5 0.0 1.8 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.31 KSA01581.1 - 5.8e-15 55.6 1.5 1.3e-14 54.5 0.0 2.4 3 0 0 3 3 2 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.6 KSA01581.1 - 4.2e-06 26.5 6.1 7.4e-06 25.7 6.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KSA01581.1 - 1.5e-05 25.2 7.5 1.5e-05 25.2 7.5 1.7 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4 PF00097.25 KSA01581.1 - 3.5e-05 23.6 9.0 7.5e-05 22.5 9.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KSA01581.1 - 5.4e-05 23.1 7.8 0.00011 22.1 7.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KSA01581.1 - 0.0049 16.9 6.5 0.011 15.7 6.5 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KSA01581.1 - 0.0054 16.6 6.8 0.011 15.6 6.8 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 KSA01581.1 - 0.23 11.2 3.0 0.55 10.0 3.0 1.7 1 0 0 1 1 1 0 RING-like zinc finger zf-C3HC4_4 PF15227.6 KSA01581.1 - 0.59 10.3 7.3 1.4 9.1 7.3 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 KSA01581.1 - 1 9.7 4.7 2.5 8.4 4.7 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KSA01581.1 - 1.5 8.8 8.5 3 7.7 8.5 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 KSA01581.1 - 2.5 8.0 5.1 5.8 6.8 5.1 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain MOZ_SAS PF01853.18 KSA01582.1 - 7.1e-48 162.6 0.5 1.2e-47 161.9 0.1 1.5 2 0 0 2 2 2 1 MOZ/SAS family zf-MYST PF17772.1 KSA01582.1 - 1.9e-09 37.0 4.3 2.5e-05 23.8 1.7 2.5 2 0 0 2 2 2 2 MYST family zinc finger domain Acetyltransf_7 PF13508.7 KSA01582.1 - 0.076 13.4 0.0 0.18 12.2 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain CBFD_NFYB_HMF PF00808.23 KSA01583.1 - 1.2e-07 31.9 0.1 3.5e-07 30.4 0.1 1.9 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T_C PF15511.6 KSA01583.1 - 2.1e-07 31.0 0.2 4e-07 30.1 0.2 1.5 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 KSA01583.1 - 3e-06 27.6 2.7 3.3e-06 27.5 0.0 2.2 2 1 1 3 3 3 1 Core histone H2A/H2B/H3/H4 DUF2722 PF10846.8 KSA01583.1 - 0.007 15.4 8.8 0.0084 15.1 8.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) CDK5_activator PF03261.15 KSA01583.1 - 0.029 13.9 5.1 0.036 13.6 5.1 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein TAFII28 PF04719.14 KSA01583.1 - 0.085 13.0 0.1 0.15 12.2 0.1 1.4 1 0 0 1 1 1 0 hTAFII28-like protein conserved region DUF2167 PF09935.9 KSA01583.1 - 2.2 7.4 6.9 8.4 5.5 4.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2167) Synaptobrevin PF00957.21 KSA01584.1 - 2.6e-22 78.4 0.5 2.6e-22 78.4 0.5 1.7 2 0 0 2 2 2 1 Synaptobrevin HA2 PF04408.23 KSA01585.1 - 5.4e-28 97.4 0.0 5.4e-28 97.4 0.0 3.5 3 1 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KSA01585.1 - 2.1e-12 47.4 0.1 2.6e-10 40.6 0.0 3.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 KSA01585.1 - 4.9e-09 36.4 0.1 9.1e-08 32.4 0.0 2.7 3 0 0 3 3 3 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 KSA01585.1 - 7e-08 32.4 0.0 1.5e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KSA01585.1 - 1.6e-06 28.5 0.4 2.1e-05 24.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 KSA01585.1 - 0.024 14.0 0.0 0.07 12.5 0.0 1.7 1 0 0 1 1 1 0 KaiC AAA_19 PF13245.6 KSA01585.1 - 0.025 14.9 0.0 0.06 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 KSA01585.1 - 0.042 12.9 0.0 0.086 11.9 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein ResIII PF04851.15 KSA01585.1 - 0.13 12.3 7.1 0.4 10.7 0.0 4.1 4 0 0 4 4 4 0 Type III restriction enzyme, res subunit DUF1573 PF07610.11 KSA01586.1 - 0.029 14.4 0.6 0.26 11.4 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1573) hGDE_N PF14699.6 KSA01586.1 - 0.35 11.0 2.0 8.3 6.6 0.0 4.0 5 0 0 5 5 5 0 N-terminal domain from the human glycogen debranching enzyme Pterin_4a PF01329.19 KSA01587.1 - 7.6e-21 74.1 0.4 1.5e-20 73.2 0.4 1.4 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase DUF5121 PF17165.4 KSA01587.1 - 0.034 14.6 0.1 0.055 13.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5121) PA28_alpha PF02251.18 KSA01587.1 - 0.071 13.2 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Proteasome activator pa28 alpha subunit Adap_comp_sub PF00928.21 KSA01588.1 - 1.1e-54 185.7 4.9 2.5e-54 184.4 4.9 1.6 1 1 0 1 1 1 1 Adaptor complexes medium subunit family HAD_2 PF13419.6 KSA01589.1 - 8.5e-11 42.3 0.0 3.1e-10 40.4 0.0 1.9 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KSA01589.1 - 2e-07 31.5 0.0 3.8e-07 30.6 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KSA01589.1 - 0.00024 21.1 0.0 0.0005 20.1 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 KSA01589.1 - 0.093 12.8 0.0 2.3 8.4 0.0 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Glyco_hydro_76 PF03663.14 KSA01590.1 - 2.7e-145 484.5 17.0 3.2e-145 484.3 17.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 KSA01590.1 - 0.25 10.4 9.3 0.043 12.9 1.1 2.7 1 1 0 3 3 3 0 Glycosyl Hydrolase Family 88 MatE PF01554.18 KSA01591.1 - 1.1e-60 204.0 33.8 2.8e-37 127.9 10.3 2.4 2 0 0 2 2 2 2 MatE Bromodomain PF00439.25 KSA01592.1 - 0.0023 18.0 0.1 0.007 16.4 0.1 1.8 1 0 0 1 1 1 1 Bromodomain Nramp PF01566.18 KSA01593.1 - 1.5e-90 303.8 15.6 2.3e-51 174.8 4.0 2.2 2 0 0 2 2 2 2 Natural resistance-associated macrophage protein Nfu_N PF08712.11 KSA01595.1 - 9.4e-28 96.1 0.1 2.7e-27 94.7 0.1 1.8 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 KSA01595.1 - 7.4e-27 93.3 0.1 1.3e-26 92.5 0.1 1.4 1 0 0 1 1 1 1 NifU-like domain YojJ PF10372.9 KSA01595.1 - 0.0058 16.7 1.7 0.014 15.5 1.7 1.6 1 0 0 1 1 1 1 Bacterial membrane-spanning protein N-terminus RhoGAP PF00620.27 KSA01595.1 - 0.0076 16.1 0.2 0.021 14.6 0.1 1.7 2 0 0 2 2 2 1 RhoGAP domain DUF445 PF04286.12 KSA01595.1 - 0.036 13.9 1.2 0.051 13.4 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) DUF5394 PF17372.2 KSA01595.1 - 0.11 12.0 1.4 0.13 11.8 0.2 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5394) PLA2_B PF01735.18 KSA01596.1 - 5e-164 546.3 6.5 9.5e-164 545.4 6.5 1.4 1 1 0 1 1 1 1 Lysophospholipase catalytic domain IBR PF01485.21 KSA01596.1 - 0.02 15.1 2.3 0.061 13.6 2.3 1.8 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Patatin PF01734.22 KSA01596.1 - 0.038 14.2 0.2 0.092 12.9 0.1 1.8 2 0 0 2 2 2 0 Patatin-like phospholipase Abhydrolase_1 PF00561.20 KSA01597.1 - 3.3e-08 33.5 1.0 5.7e-07 29.4 0.4 2.4 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KSA01597.1 - 3.3e-07 31.1 0.0 2.8e-06 28.1 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KSA01597.1 - 3.5e-07 29.7 0.0 0.0013 18.1 0.0 2.8 3 0 0 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 KSA01597.1 - 0.0032 17.3 0.0 0.18 11.6 0.0 2.4 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase DUF1788 PF08747.11 KSA01597.1 - 0.012 15.7 0.1 0.028 14.4 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1788) DUF915 PF06028.11 KSA01597.1 - 0.014 14.8 0.3 0.86 8.9 0.1 2.4 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Transp_cyt_pur PF02133.15 KSA01598.1 - 1.6e-144 482.0 32.1 1.9e-144 481.8 32.1 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Whi5 PF08528.11 KSA01599.1 - 0.013 15.1 3.8 0.013 15.1 3.8 2.0 2 0 0 2 2 2 0 Whi5 like Autophagy_N PF03986.13 KSA01600.1 - 6.1e-45 152.5 1.9 6.1e-45 152.5 1.9 2.3 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_C PF10381.9 KSA01600.1 - 2e-16 59.2 1.0 5.3e-16 57.8 1.0 1.8 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Autophagy_act_C PF03987.15 KSA01600.1 - 1.7e-13 51.0 0.1 3.4e-13 50.0 0.1 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain RNA_pol_3_Rpc31 PF11705.8 KSA01600.1 - 0.05 13.9 0.5 0.05 13.9 0.5 2.2 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 DUF1178 PF06676.11 KSA01600.1 - 0.085 13.2 1.1 0.21 12.0 1.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1178) DUF4746 PF15928.5 KSA01600.1 - 0.36 10.2 8.9 0.15 11.5 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) CPSF100_C PF13299.6 KSA01600.1 - 0.51 10.5 5.6 10 6.3 0.7 3.1 3 0 0 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal DUF4820 PF16091.5 KSA01600.1 - 1.1 8.6 16.2 0.064 12.6 2.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) TRAP_alpha PF03896.16 KSA01600.1 - 1.4 8.1 9.9 0.19 10.9 0.9 2.3 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Myc_N PF01056.18 KSA01600.1 - 2.2 8.1 13.7 0.061 13.2 4.8 2.1 2 0 0 2 2 2 0 Myc amino-terminal region BUD22 PF09073.10 KSA01600.1 - 2.2 7.5 16.7 3.3 6.9 4.6 2.0 2 0 0 2 2 2 0 BUD22 Roughex PF06020.11 KSA01600.1 - 5.3 6.0 10.2 0.14 11.2 0.4 2.1 2 0 0 2 2 2 0 Drosophila roughex protein Zip PF02535.22 KSA01600.1 - 5.4 6.1 7.0 17 4.5 7.0 1.8 1 1 0 1 1 1 0 ZIP Zinc transporter LCAT PF02450.15 KSA01601.1 - 1.8e-57 195.3 0.3 2.6e-57 194.8 0.3 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF1749 PF08538.10 KSA01601.1 - 0.02 14.0 0.0 0.042 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Peptidase_M50 PF02163.22 KSA01601.1 - 0.1 11.9 0.0 0.1 11.8 0.0 1.1 1 0 0 1 1 1 0 Peptidase family M50 EIIBC-GUT_N PF03612.14 KSA01601.1 - 0.13 12.0 0.1 0.22 11.3 0.1 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Abhydrolase_6 PF12697.7 KSA01601.1 - 0.13 12.8 0.0 0.28 11.7 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family LCAT PF02450.15 KSA01602.1 - 1.6e-44 152.7 0.0 1.9e-44 152.4 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase zf-C2H2_jaz PF12171.8 KSA01603.1 - 0.0061 16.8 2.1 0.017 15.4 2.1 1.8 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KSA01603.1 - 0.016 15.5 0.7 0.042 14.2 0.7 1.7 1 0 0 1 1 1 0 Zinc-finger of C2H2 type DUF1899 PF08953.11 KSA01604.1 - 5.2e-34 115.9 0.2 1.4e-33 114.6 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.32 KSA01604.1 - 2.1e-22 79.0 2.4 3.8e-06 27.5 0.0 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat WD40_4 PF16300.5 KSA01604.1 - 2.3e-18 65.8 0.0 4.2e-18 65.0 0.0 1.4 1 0 0 1 1 1 1 Type of WD40 repeat ANAPC4_WD40 PF12894.7 KSA01604.1 - 1e-06 28.9 0.0 3.7e-05 24.0 0.0 3.2 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain HC2 PF07382.11 KSA01604.1 - 8.1e-06 26.0 25.1 8.1e-06 26.0 25.1 1.9 2 0 0 2 2 2 1 Histone H1-like nucleoprotein HC2 Nup160 PF11715.8 KSA01604.1 - 5.2e-05 22.1 0.1 0.24 10.0 0.0 2.6 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KSA01604.1 - 0.0019 17.3 0.0 1 8.3 0.0 2.5 1 1 1 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein LAP1C PF05609.12 KSA01604.1 - 5.9 5.9 30.7 8.1 5.4 30.7 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) RasGAP_C PF03836.15 KSA01605.1 - 4.9e-43 146.6 10.2 4.9e-43 146.6 10.2 2.9 3 0 0 3 3 3 1 RasGAP C-terminus RasGAP PF00616.19 KSA01605.1 - 1e-36 126.6 4.3 1e-36 126.6 4.3 2.9 3 0 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase CH PF00307.31 KSA01605.1 - 1.4e-12 47.8 0.9 5.6e-12 45.8 0.9 2.2 1 0 0 1 1 1 1 Calponin homology (CH) domain IQ PF00612.27 KSA01605.1 - 9.8e-09 34.3 12.9 0.19 11.6 0.0 9.3 10 0 0 10 10 10 2 IQ calmodulin-binding motif AlphaC_C PF17480.2 KSA01605.1 - 5 7.2 7.6 5.9 7.0 0.5 4.0 3 0 0 3 3 3 0 AlphaC C-terminal Mis14 PF08641.12 KSA01606.1 - 5.9e-33 114.0 3.6 5.9e-33 114.0 3.6 1.8 2 0 0 2 2 2 1 Kinetochore protein Mis14 like HD_2 PF12917.7 KSA01606.1 - 0.099 12.4 0.9 0.21 11.3 0.2 1.8 2 1 0 2 2 2 0 HD containing hydrolase-like enzyme Exonuc_VII_L PF02601.15 KSA01606.1 - 0.25 10.9 3.1 0.96 9.0 1.5 1.9 1 1 0 2 2 2 0 Exonuclease VII, large subunit Helo_like_N PF17111.5 KSA01606.1 - 4 6.8 7.7 0.47 9.8 0.8 2.6 2 1 1 3 3 3 0 Fungal N-terminal domain of STAND proteins ATP-synt_C PF00137.21 KSA01607.1 - 8.3e-30 102.9 30.1 1.8e-18 66.6 8.4 2.2 2 0 0 2 2 2 2 ATP synthase subunit C TIP49 PF06068.13 KSA01608.1 - 2e-158 527.2 2.6 2.5e-158 526.9 2.6 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 KSA01608.1 - 5.4e-21 74.5 0.5 1.8e-20 72.8 0.4 2.0 2 0 0 2 2 2 1 TIP49 AAA-lid domain AAA PF00004.29 KSA01608.1 - 1.8e-08 34.9 1.0 5.4e-05 23.6 0.1 2.8 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KSA01608.1 - 2.2e-07 30.8 0.7 0.0015 18.3 0.1 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain DnaB_C PF03796.15 KSA01608.1 - 4.5e-05 22.9 0.3 8.2e-05 22.1 0.3 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_22 PF13401.6 KSA01608.1 - 0.00033 21.0 0.0 0.067 13.5 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.6 KSA01608.1 - 0.00051 20.4 0.3 0.0024 18.2 0.3 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KSA01608.1 - 0.0016 18.9 0.3 0.0061 17.0 0.3 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.6 KSA01608.1 - 0.0054 17.0 0.1 0.014 15.6 0.1 1.7 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KSA01608.1 - 0.016 14.6 0.9 0.26 10.6 0.4 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KSA01608.1 - 0.027 14.5 0.1 2.4 8.1 0.0 2.6 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 KSA01608.1 - 0.075 12.5 0.3 0.51 9.8 0.0 2.4 3 0 0 3 3 3 0 P-loop containing dynein motor region AAA_25 PF13481.6 KSA01608.1 - 0.13 11.9 0.1 0.26 10.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain AMP-binding PF00501.28 KSA01609.1 - 2.5e-65 220.8 0.0 8.2e-65 219.0 0.0 1.7 2 0 0 2 2 2 1 AMP-binding enzyme AMP-binding PF00501.28 KSA01610.1 - 2.8e-23 82.2 0.0 5.6e-23 81.2 0.1 1.5 2 0 0 2 2 2 1 AMP-binding enzyme AMP-binding PF00501.28 KSA01611.1 - 1.1e-31 110.0 0.0 1.5e-31 109.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme TPP_enzyme_N PF02776.18 KSA01612.1 - 7.5e-20 71.2 0.0 1.4e-19 70.4 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KSA01612.1 - 1.2e-17 64.1 0.0 2.1e-16 60.1 0.0 2.4 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KSA01612.1 - 7.3e-07 29.0 0.0 1.5e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TBCC PF07986.12 KSA01613.1 - 8.8e-12 44.8 5.0 1.5e-11 44.1 5.0 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C AA_permease PF00324.21 KSA01614.1 - 1e-119 400.3 42.9 1.2e-119 400.0 42.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KSA01614.1 - 5.7e-31 107.8 45.2 1.1e-30 106.9 44.9 1.5 1 1 0 1 1 1 1 Amino acid permease PFK PF00365.20 KSA01615.1 - 2.3e-181 601.4 6.4 9.5e-105 350.0 2.8 2.2 2 0 0 2 2 2 2 Phosphofructokinase DAGK_cat PF00781.24 KSA01615.1 - 0.0076 15.9 0.0 0.021 14.4 0.0 1.8 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Porin_3 PF01459.22 KSA01616.1 - 7e-86 288.0 0.5 8.4e-86 287.8 0.5 1.1 1 0 0 1 1 1 1 Eukaryotic porin Inp1 PF12634.7 KSA01617.1 - 9.6e-16 58.0 0.1 9.6e-16 58.0 0.1 3.8 2 2 0 2 2 2 1 Inheritance of peroxisomes protein 1 Rhomboid PF01694.22 KSA01618.1 - 6.5e-14 52.2 13.7 6.5e-14 52.2 13.7 1.4 2 0 0 2 2 2 1 Rhomboid family Med9 PF07544.13 KSA01619.1 - 6.6e-22 77.4 1.9 6.6e-22 77.4 1.9 2.0 2 0 0 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 Pkinase PF00069.25 KSA01620.1 - 4.2e-40 137.8 0.1 2.4e-25 89.4 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KSA01620.1 - 2.7e-17 62.9 0.0 1e-11 44.7 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KSA01620.1 - 0.045 13.7 0.0 0.079 12.9 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Apidaecin PF00807.17 KSA01621.1 - 6.3 7.0 9.3 40 4.4 0.0 2.5 2 0 0 2 2 2 0 Apidaecin eIF-5_eIF-2B PF01873.17 KSA01622.1 - 6.8e-39 132.4 0.0 1.1e-38 131.7 0.0 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 IF2_N PF04760.15 KSA01622.1 - 0.015 15.1 0.0 0.083 12.7 0.0 2.1 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region GET2 PF08690.10 KSA01622.1 - 0.029 14.0 1.8 0.043 13.5 1.8 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 zinc_ribbon_6 PF14599.6 KSA01622.1 - 0.09 12.8 0.5 2 8.5 0.1 2.4 2 0 0 2 2 2 0 Zinc-ribbon zf-HYPF PF07503.12 KSA01622.1 - 0.1 12.4 0.2 18 5.2 0.0 2.8 2 0 0 2 2 2 0 HypF finger DUF2752 PF10825.8 KSA01622.1 - 0.13 12.4 0.1 0.23 11.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2752) TMEM214 PF10151.9 KSA01622.1 - 1.4 7.3 8.9 2.3 6.6 8.9 1.2 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator Ank_2 PF12796.7 KSA01623.1 - 3.3e-29 101.3 2.3 1.1e-14 54.8 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KSA01623.1 - 1e-15 57.9 0.2 3.6e-11 43.4 0.1 1.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KSA01623.1 - 1.7e-15 56.9 0.3 1.5e-08 34.7 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KSA01623.1 - 4.4e-13 48.1 0.2 1.1e-05 25.4 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 KSA01623.1 - 5.6e-11 42.4 0.1 1.5e-05 25.3 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat CWC25 PF12542.8 KSA01623.1 - 0.085 13.8 2.4 0.18 12.7 2.4 1.4 1 0 0 1 1 1 0 Pre-mRNA splicing factor RTP1_C1 PF10363.9 KSA01624.1 - 5.5e-35 119.9 2.2 1.4e-33 115.4 0.3 3.3 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 RTP1_C2 PF10304.9 KSA01624.1 - 5.8e-09 35.5 1.3 2.4e-08 33.5 1.3 2.2 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 2 RIX1 PF08167.12 KSA01624.1 - 0.12 12.1 0.8 1.5 8.6 0.0 2.5 2 1 1 3 3 3 0 rRNA processing/ribosome biogenesis MCM_N PF14551.6 KSA01624.1 - 0.29 11.8 3.7 2.4 8.8 0.5 3.2 2 0 0 2 2 2 0 MCM N-terminal domain HSP90 PF00183.18 KSA01625.1 - 1.5e-221 736.8 35.1 1.9e-221 736.5 35.1 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 KSA01625.1 - 4.4e-15 56.2 0.0 9.6e-15 55.1 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KSA01625.1 - 4.1e-10 39.6 0.0 1.5e-09 37.8 0.0 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ubiq-assoc PF09145.10 KSA01625.1 - 0.072 13.1 0.0 1.9 8.5 0.0 2.6 2 0 0 2 2 2 0 Ubiquitin-associated Cofac_haem_bdg PF04187.13 KSA01625.1 - 0.075 13.0 0.1 0.23 11.4 0.1 1.8 1 0 0 1 1 1 0 Haem-binding uptake, Tiki superfamily, ChaN HAD_SAK_2 PF18143.1 KSA01625.1 - 0.1 12.9 1.7 0.19 12.0 0.1 2.3 2 0 0 2 2 2 0 HAD domain in Swiss Army Knife RNA repair proteins DUF2052 PF09747.9 KSA01625.1 - 5 7.2 17.4 1.3 9.1 8.4 2.6 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) XPA_C PF05181.12 KSA01626.1 - 3.7e-21 74.8 0.2 7.5e-21 73.8 0.2 1.6 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.18 KSA01626.1 - 0.0092 16.0 1.5 0.0092 16.0 1.5 2.3 3 0 0 3 3 3 1 XPA protein N-terminal DUF3619 PF12279.8 KSA01626.1 - 0.078 13.3 1.2 14 6.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3619) GPR15L PF15854.5 KSA01626.1 - 0.13 12.6 0.5 0.46 10.7 0.5 2.0 1 0 0 1 1 1 0 G-protein coupled receptor ligand 15 FYVE PF01363.21 KSA01626.1 - 0.3 11.2 2.1 0.3 11.3 0.6 1.8 2 0 0 2 2 2 0 FYVE zinc finger DUF2680 PF10925.8 KSA01626.1 - 1.4 9.0 4.5 35 4.5 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2680) CALM_bind PF16025.5 KSA01626.1 - 3.6 8.1 14.5 0.86 10.1 1.1 3.4 3 0 0 3 3 3 0 Calcium-dependent calmodulin binding MFS_1 PF07690.16 KSA01627.1 - 4.3e-07 29.2 24.6 0.00023 20.2 13.5 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily V_ATPase_I PF01496.19 KSA01627.1 - 0.035 12.0 0.1 0.052 11.5 0.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MFS_1_like PF12832.7 KSA01627.1 - 2 7.2 18.0 0.0099 14.8 3.9 2.3 2 1 0 2 2 2 0 MFS_1 like family Spermine_synth PF01564.17 KSA01628.1 - 5.2e-75 251.0 0.0 9.3e-75 250.2 0.0 1.4 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 KSA01628.1 - 2.2e-23 81.9 0.1 4.2e-23 81.0 0.1 1.5 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_31 PF13847.6 KSA01628.1 - 0.0003 20.6 0.0 0.00073 19.4 0.0 1.6 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KSA01628.1 - 0.0014 19.3 0.0 0.0025 18.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KSA01628.1 - 0.0021 18.8 0.0 0.0042 17.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Glycos_transf_1 PF00534.20 KSA01629.1 - 2.9e-10 39.9 0.0 4.9e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KSA01629.1 - 2.4e-08 34.5 0.0 5e-08 33.5 0.0 1.5 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KSA01629.1 - 3.9e-06 27.0 0.0 7e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 KSA01629.1 - 0.041 14.3 0.0 0.091 13.2 0.0 1.6 1 1 0 1 1 1 0 Glycosyl transferases group 1 Hist_deacetyl PF00850.19 KSA01630.1 - 3.8e-76 256.5 0.0 5.6e-76 255.9 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain IMS PF00817.20 KSA01631.1 - 2.3e-35 121.8 0.0 6.1e-35 120.4 0.0 1.8 1 0 0 1 1 1 1 impB/mucB/samB family BRCT_2 PF16589.5 KSA01631.1 - 3.1e-13 49.9 0.0 7.6e-13 48.7 0.0 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain IMS_C PF11799.8 KSA01631.1 - 5.7e-11 43.2 0.0 1.6e-10 41.7 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain REV1_C PF16727.5 KSA01631.1 - 1.7e-08 34.7 0.0 3.9e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 DNA repair protein REV1 C-terminal domain BRCT PF00533.26 KSA01631.1 - 4.1e-07 30.3 0.1 1.6e-06 28.3 0.1 2.1 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 KSA01631.1 - 1.9e-06 28.1 0.0 5.7e-06 26.5 0.0 1.9 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain IMS_HHH PF11798.8 KSA01631.1 - 0.00014 22.0 1.1 0.0013 18.9 0.0 3.2 4 0 0 4 4 4 1 IMS family HHH motif mCpol PF18182.1 KSA01631.1 - 0.047 14.0 0.3 0.17 12.2 0.0 2.0 2 0 0 2 2 2 0 minimal CRISPR polymerase domain PTCB-BRCT PF12738.7 KSA01631.1 - 0.093 12.7 0.1 0.22 11.5 0.1 1.6 1 0 0 1 1 1 0 twin BRCT domain EF-hand_1 PF00036.32 KSA01632.1 - 1.9e-28 95.8 4.5 9.5e-09 34.2 0.0 3.2 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 KSA01632.1 - 3.5e-24 85.1 1.2 1.5e-15 57.4 0.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KSA01632.1 - 1.5e-22 79.1 3.8 4.7e-09 36.0 0.3 3.0 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 KSA01632.1 - 1.6e-21 74.8 4.5 4.8e-08 32.1 0.0 3.3 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 KSA01632.1 - 2.2e-18 64.5 3.5 1.6e-08 33.8 0.0 3.3 3 0 0 3 3 3 3 EF-hand domain EF-hand_9 PF14658.6 KSA01632.1 - 4.7e-09 36.4 0.3 0.00045 20.5 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 KSA01632.1 - 3.3e-08 33.4 2.3 0.0011 18.9 0.2 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 KSA01632.1 - 3.6e-07 30.3 5.7 6e-05 23.2 1.1 3.0 1 1 2 3 3 3 3 Dockerin type I domain SPARC_Ca_bdg PF10591.9 KSA01632.1 - 1.2e-06 28.9 0.1 0.00012 22.3 0.0 2.1 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 KSA01632.1 - 1.2e-05 25.3 0.0 0.21 11.6 0.0 2.8 3 0 0 3 3 3 2 Uncharacterised protein family (UPF0154) EF-hand_11 PF08976.11 KSA01632.1 - 8e-05 23.5 0.0 0.0038 18.1 0.0 2.0 1 1 1 2 2 2 1 EF-hand domain Poly_export PF02563.16 KSA01632.1 - 0.00029 21.0 0.0 0.0099 16.1 0.0 2.2 1 1 1 2 2 2 1 Polysaccharide biosynthesis/export protein TerB PF05099.13 KSA01632.1 - 0.00096 19.1 0.4 0.011 15.7 0.1 2.0 1 1 0 2 2 2 1 Tellurite resistance protein TerB DUF5580 PF17743.1 KSA01632.1 - 0.017 13.7 0.0 0.018 13.6 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5580) EF-hand_10 PF14788.6 KSA01632.1 - 0.057 13.3 0.7 0.14 12.1 0.0 2.0 2 1 0 2 2 2 0 EF hand Spore_III_AB PF09548.10 KSA01632.1 - 0.095 12.8 0.0 0.13 12.4 0.0 1.1 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) RuvA_C PF07499.13 KSA01632.1 - 0.16 12.4 0.2 0.45 11.0 0.1 1.8 2 0 0 2 2 2 0 RuvA, C-terminal domain VCBS PF13517.6 KSA01632.1 - 0.29 11.7 4.9 2.2 8.9 5.0 2.3 1 1 1 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Mcp5_PH PF12814.7 KSA01633.1 - 3.2e-45 153.2 2.2 1.6e-44 150.9 0.3 3.0 2 0 0 2 2 2 1 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.29 KSA01633.1 - 0.00013 22.4 0.0 0.00089 19.7 0.0 2.6 1 0 0 1 1 1 1 PH domain Spectrin_like PF18373.1 KSA01633.1 - 0.0028 17.7 0.6 0.032 14.3 0.1 3.3 2 0 0 2 2 2 1 Spectrin like domain DUF771 PF05595.11 KSA01633.1 - 0.014 15.4 30.5 18 5.4 0.1 12.4 10 4 0 10 10 10 0 Domain of unknown function (DUF771) Terminase_4 PF05119.12 KSA01633.1 - 0.068 13.6 0.7 82 3.7 0.0 5.4 5 0 0 5 5 5 0 Phage terminase, small subunit Homeodomain PF00046.29 KSA01633.1 - 0.094 12.6 3.6 13 5.7 0.1 5.6 5 0 0 5 5 5 0 Homeodomain DUF5085 PF16895.5 KSA01633.1 - 0.52 10.6 6.3 2.5 8.4 0.2 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF5085) PCI PF01399.27 KSA01634.1 - 0.013 16.0 0.0 0.072 13.6 0.0 2.4 1 1 0 1 1 1 0 PCI domain eIF3m_C_helix PF18005.1 KSA01634.1 - 0.037 13.7 0.3 0.098 12.4 0.3 1.7 1 0 0 1 1 1 0 eIF3 subunit M, C-terminal helix Pkinase PF00069.25 KSA01635.1 - 7.2e-68 228.8 0.1 1.4e-67 227.9 0.1 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KSA01635.1 - 1.1e-37 129.7 0.0 2e-37 128.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KSA01635.1 - 7.6e-06 25.4 0.0 1.6e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KSA01635.1 - 0.031 13.6 0.3 0.11 11.8 0.1 1.9 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SelA PF03841.13 KSA01635.1 - 0.18 10.8 0.5 0.49 9.3 0.3 1.7 2 0 0 2 2 2 0 L-seryl-tRNA selenium transferase SUV3_C PF12513.8 KSA01636.1 - 1.3e-14 53.8 0.9 2.9e-14 52.7 0.9 1.6 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.31 KSA01636.1 - 8.8e-13 48.6 0.5 3.8e-12 46.5 0.0 2.3 2 1 1 3 3 3 1 Helicase conserved C-terminal domain SKI PF01202.22 KSA01637.1 - 8.1e-11 42.3 0.0 1.1e-10 41.9 0.0 1.2 1 0 0 1 1 1 1 Shikimate kinase AAA_18 PF13238.6 KSA01637.1 - 8.9e-09 36.0 0.0 1.7e-08 35.1 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KSA01637.1 - 6.4e-07 29.6 0.0 9.1e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.20 KSA01637.1 - 1.1e-06 28.6 0.0 1.4e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase Cytidylate_kin PF02224.18 KSA01637.1 - 1.1e-05 25.3 0.0 2.1e-05 24.4 0.0 1.6 2 0 0 2 2 2 1 Cytidylate kinase dNK PF01712.19 KSA01637.1 - 0.00011 22.1 0.1 0.16 11.8 0.0 2.2 2 0 0 2 2 2 2 Deoxynucleoside kinase AAA PF00004.29 KSA01637.1 - 0.00027 21.4 0.1 0.00059 20.3 0.1 1.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 KSA01637.1 - 0.00072 20.0 0.0 0.0013 19.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 KSA01637.1 - 0.001 19.6 0.0 0.0013 19.3 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_30 PF13604.6 KSA01637.1 - 0.0013 18.5 0.3 0.0021 17.8 0.3 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KSA01637.1 - 0.0014 18.9 0.0 0.0027 18.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KSA01637.1 - 0.0016 18.8 0.0 0.0027 18.1 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.6 KSA01637.1 - 0.0016 18.7 0.1 0.0028 17.9 0.1 1.7 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 KSA01637.1 - 0.0054 16.2 0.5 0.0092 15.4 0.5 1.4 1 0 0 1 1 1 1 PhoH-like protein AAA_5 PF07728.14 KSA01637.1 - 0.0085 16.1 0.0 0.02 14.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Thymidylate_kin PF02223.17 KSA01637.1 - 0.0097 15.6 0.1 0.029 14.0 0.0 1.7 2 0 0 2 2 2 1 Thymidylate kinase AAA_19 PF13245.6 KSA01637.1 - 0.024 15.0 0.3 0.046 14.1 0.3 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KSA01637.1 - 0.031 13.4 0.6 0.35 10.0 0.1 2.2 2 0 0 2 2 2 0 NB-ARC domain DUF2075 PF09848.9 KSA01637.1 - 0.033 13.4 0.2 0.046 13.0 0.2 1.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.12 KSA01637.1 - 0.042 13.1 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin ATP_bind_2 PF03668.15 KSA01637.1 - 0.046 13.0 0.0 0.28 10.4 0.0 1.9 2 0 0 2 2 2 0 P-loop ATPase protein family CoaE PF01121.20 KSA01637.1 - 0.051 13.3 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Dephospho-CoA kinase Cytidylate_kin2 PF13189.6 KSA01637.1 - 0.051 13.7 0.0 0.093 12.8 0.0 1.6 1 1 0 1 1 1 0 Cytidylate kinase-like family RNA_helicase PF00910.22 KSA01637.1 - 0.06 13.7 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 KSA01637.1 - 0.064 13.0 0.0 0.07 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain CPT PF07931.12 KSA01637.1 - 0.072 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_25 PF13481.6 KSA01637.1 - 0.081 12.5 0.3 0.14 11.7 0.3 1.4 1 1 0 1 1 1 0 AAA domain RuvB_N PF05496.12 KSA01637.1 - 0.092 12.5 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 KSA01637.1 - 0.093 12.6 0.0 0.27 11.2 0.0 1.7 2 0 0 2 2 2 0 NACHT domain T2SSE PF00437.20 KSA01637.1 - 0.11 11.5 0.4 0.17 11.0 0.4 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.6 KSA01637.1 - 0.13 12.7 1.0 0.5 10.8 0.3 1.9 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 KSA01637.1 - 0.36 10.4 1.6 1.6 8.3 0.4 2.4 2 1 1 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain adh_short PF00106.25 KSA01638.1 - 4.4e-18 65.5 0.0 2.4e-07 30.4 0.0 3.1 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KSA01638.1 - 1.1e-07 31.7 0.0 1e-05 25.2 0.0 2.5 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 KSA01638.1 - 5e-05 22.8 1.6 0.00017 21.0 1.6 1.8 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.10 KSA01638.1 - 0.14 12.1 0.0 0.3 11.0 0.0 1.5 1 1 0 1 1 1 0 KR domain SGT1 PF07093.11 KSA01639.1 - 3.2e-24 85.3 3.1 3.2e-24 85.3 3.1 2.4 2 1 0 2 2 2 1 SGT1 protein Spore_Cse60 PF10957.8 KSA01639.1 - 0.01 15.8 2.4 0.4 10.7 0.0 3.4 3 0 0 3 3 3 0 Sporulation protein Cse60 Thiolase_N PF00108.23 KSA01640.1 - 1.4e-94 316.3 2.8 1.8e-94 315.9 2.8 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KSA01640.1 - 2.5e-46 156.3 0.3 6.8e-46 154.9 0.3 1.8 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KSA01640.1 - 8.7e-05 22.2 0.3 0.00022 20.9 0.3 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ATP-synt_Eps PF04627.13 KSA01640.1 - 0.15 12.1 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial ATP synthase epsilon chain FLILHELTA PF10306.9 KSA01641.1 - 5.5e-28 97.2 0.4 9.3e-28 96.5 0.4 1.4 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA Pkinase PF00069.25 KSA01642.1 - 3.9e-65 219.8 0.0 4.7e-65 219.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KSA01642.1 - 1.9e-23 83.1 0.0 2.5e-23 82.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KSA01642.1 - 6.8e-05 22.3 0.0 0.00016 21.1 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 KSA01642.1 - 0.00042 20.3 0.0 0.0044 17.0 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KSA01642.1 - 0.0075 15.9 0.1 0.014 14.9 0.1 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase FTA2 PF13095.6 KSA01642.1 - 0.011 15.4 0.1 0.031 13.9 0.0 1.7 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 KSA01642.1 - 0.089 11.6 0.0 1.6 7.5 0.0 2.1 2 0 0 2 2 2 0 Fungal protein kinase Kdo PF06293.14 KSA01642.1 - 0.093 12.1 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Nucleo_LEF-12 PF06256.11 KSA01642.1 - 0.29 10.9 2.9 0.95 9.2 2.3 2.0 1 1 1 2 2 2 0 Nucleopolyhedrovirus LEF-12 protein MADF_DNA_bdg PF10545.9 KSA01643.1 - 0.021 15.2 2.3 0.021 15.2 2.3 1.9 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF1542 PF07564.11 KSA01643.1 - 0.5 10.5 7.5 0.25 11.5 1.8 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) Pkinase PF00069.25 KSA01644.1 - 6.5e-22 78.2 0.0 8.1e-22 77.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KSA01644.1 - 1.7e-07 30.8 0.0 2.4e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KSA01644.1 - 0.0021 17.4 0.0 0.0032 16.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KSA01644.1 - 0.071 13.0 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KSA01644.1 - 0.18 10.6 0.0 0.24 10.1 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 KSA01645.1 - 1.7e-59 201.4 0.9 6e-58 196.3 0.2 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KSA01645.1 - 2.4e-27 95.9 0.1 5.5e-26 91.4 0.0 2.4 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KSA01645.1 - 0.00086 18.3 0.1 0.0017 17.4 0.0 1.5 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KSA01645.1 - 0.012 14.9 0.0 0.021 14.2 0.0 1.5 1 0 0 1 1 1 0 Kinase-like Imm7 PF15585.6 KSA01645.1 - 0.079 13.2 0.0 0.39 11.0 0.0 2.0 2 0 0 2 2 2 0 Immunity protein 7 DUF2098 PF09871.9 KSA01645.1 - 0.12 12.7 0.3 0.26 11.6 0.3 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2098) FA_hydroxylase PF04116.13 KSA01646.1 - 1.6e-22 80.3 16.4 1.6e-22 80.3 16.4 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily AMPKBI PF04739.15 KSA01646.1 - 0.048 13.9 0.1 0.048 13.9 0.1 1.7 2 0 0 2 2 2 0 5'-AMP-activated protein kinase beta subunit, interaction domain Porphobil_deam PF01379.20 KSA01647.1 - 3.1e-70 235.8 0.0 3.9e-70 235.5 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 KSA01647.1 - 5.9e-24 84.2 0.0 1e-23 83.5 0.0 1.4 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain ERCC4 PF02732.15 KSA01649.1 - 1.2e-21 77.5 0.0 1.2e-21 77.5 0.0 3.1 4 0 0 4 4 4 1 ERCC4 domain RMI1_N PF08585.12 KSA01650.1 - 3.6e-13 49.8 0.0 4.6e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 RecQ mediated genome instability protein E2 PF08199.11 KSA01650.1 - 1.1 9.2 4.6 5.3 7.1 4.6 2.0 1 1 0 1 1 1 0 Bacteriophage E2-like protein MTHFR PF02219.17 KSA01651.1 - 2.6e-102 342.0 0.0 3.9e-102 341.4 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase ATG27 PF09451.10 KSA01652.1 - 1.1e-60 205.8 1.6 1.3e-60 205.5 1.6 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 DUF2165 PF09933.9 KSA01652.1 - 0.014 15.5 0.1 0.023 14.8 0.1 1.3 1 0 0 1 1 1 0 Predicted small integral membrane protein (DUF2165) Ldh_1_N PF00056.23 KSA01653.1 - 2.6e-44 150.7 0.4 4.3e-44 150.0 0.4 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 KSA01653.1 - 3.3e-39 134.5 0.0 6.7e-39 133.5 0.0 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_4 PF02056.16 KSA01653.1 - 0.019 14.5 0.2 0.19 11.3 0.1 2.2 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase 3Beta_HSD PF01073.19 KSA01653.1 - 0.041 12.9 0.0 0.063 12.3 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Beta-lactamase PF00144.24 KSA01654.1 - 2.2e-52 178.3 0.0 2.9e-52 178.0 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Histidinol_dh PF00815.20 KSA01655.1 - 1.8e-155 517.9 0.8 2.7e-155 517.4 0.8 1.3 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.18 KSA01655.1 - 3.3e-21 74.9 0.2 7.9e-21 73.7 0.2 1.7 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 KSA01655.1 - 2e-14 53.8 0.1 1e-13 51.5 0.0 2.1 2 0 0 2 2 2 1 Phosphoribosyl-ATP pyrophosphohydrolase TPR_1 PF00515.28 KSA01656.1 - 1.2e-22 78.7 2.2 1.2e-06 28.1 0.0 5.9 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.6 KSA01656.1 - 1.1e-17 63.0 2.8 0.00086 19.5 0.0 5.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 KSA01656.1 - 1.9e-16 58.7 6.3 0.0018 18.2 0.0 7.2 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_11 PF13414.6 KSA01656.1 - 3.8e-15 55.3 0.8 1.7e-05 24.4 0.0 5.1 3 1 2 5 5 5 3 TPR repeat TPR_14 PF13428.6 KSA01656.1 - 3.7e-14 52.2 1.5 0.0047 17.6 0.0 5.5 2 2 3 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 KSA01656.1 - 4.8e-13 48.2 3.8 0.019 15.1 0.0 6.4 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 KSA01656.1 - 1e-12 48.4 2.9 0.017 15.6 0.1 4.5 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_16 PF13432.6 KSA01656.1 - 5.1e-10 39.8 0.2 0.026 15.2 0.0 4.4 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.6 KSA01656.1 - 8.2e-08 32.3 0.0 0.0023 18.0 0.0 3.7 3 1 0 3 3 2 2 Tetratricopeptide repeat TPR_20 PF14561.6 KSA01656.1 - 8.6e-07 29.2 7.0 0.012 16.0 0.0 5.0 4 2 2 6 6 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 KSA01656.1 - 1.5e-06 28.4 0.0 0.016 15.5 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KSA01656.1 - 0.00011 22.3 1.6 0.028 14.6 0.1 3.1 2 2 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 KSA01656.1 - 0.00027 21.4 1.4 26 5.7 0.0 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 KSA01656.1 - 0.00065 19.5 0.0 5.2 7.3 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 KSA01656.1 - 0.00078 18.7 0.4 0.96 8.6 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat HSP70 PF00012.20 KSA01656.1 - 0.52 8.4 7.3 0.86 7.7 7.3 1.5 1 0 0 1 1 1 0 Hsp70 protein TFIIA PF03153.13 KSA01656.1 - 1.7 8.6 32.9 2.8 7.8 32.9 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ARID PF01388.21 KSA01657.1 - 2e-16 60.4 0.0 2e-16 60.4 0.0 3.6 3 1 0 3 3 3 1 ARID/BRIGHT DNA binding domain Glyco_transf_34 PF05637.12 KSA01658.1 - 2.3e-68 230.5 0.4 3.7e-68 229.8 0.4 1.3 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Pex2_Pex12 PF04757.14 KSA01659.1 - 3.4e-41 141.3 2.6 4.3e-41 141.0 2.6 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.6 KSA01659.1 - 1.8e-10 40.9 10.8 3.1e-10 40.2 10.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KSA01659.1 - 3.4e-08 33.2 8.5 5.8e-08 32.5 8.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KSA01659.1 - 4.2e-08 32.9 10.2 6.4e-08 32.3 10.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KSA01659.1 - 9.2e-08 31.8 10.0 1.6e-07 31.1 10.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KSA01659.1 - 8.1e-07 29.0 7.3 2.2e-06 27.5 7.3 1.8 1 1 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KSA01659.1 - 1e-06 28.5 11.1 1.7e-06 27.8 11.1 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KSA01659.1 - 1.2e-05 25.5 8.2 2.3e-05 24.6 8.2 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KSA01659.1 - 8.3e-05 22.5 5.9 0.00017 21.5 5.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KSA01659.1 - 0.00028 21.0 10.0 0.00053 20.1 10.0 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING DnaI_N PF07319.11 KSA01659.1 - 0.087 13.5 1.0 3.3 8.5 0.0 2.4 2 0 0 2 2 2 0 Primosomal protein DnaI N-terminus zf-RING_11 PF17123.5 KSA01659.1 - 0.18 11.6 3.8 0.48 10.2 3.8 1.8 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_10 PF16685.5 KSA01659.1 - 0.22 11.7 8.3 0.44 10.7 8.3 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-ANAPC11 PF12861.7 KSA01659.1 - 0.22 11.6 5.9 0.37 10.9 5.9 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 KSA01659.1 - 0.33 10.8 7.4 0.67 9.8 7.4 1.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain IBR PF01485.21 KSA01659.1 - 2.3 8.5 8.9 6.6 7.0 8.9 1.7 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain IMS PF00817.20 KSA01660.1 - 6.2e-41 139.9 0.0 1.1e-40 139.1 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family zf_UBZ PF18439.1 KSA01660.1 - 0.00011 21.7 0.2 0.0002 20.9 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger IMS_HHH PF11798.8 KSA01660.1 - 0.021 15.1 0.0 0.086 13.2 0.0 2.1 2 0 0 2 2 2 0 IMS family HHH motif Ferric_reduct PF01794.19 KSA01661.1 - 1.2e-18 67.4 22.3 3.7e-18 65.8 14.6 2.3 2 0 0 2 2 2 2 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KSA01661.1 - 9.8e-13 48.5 0.0 1.5e-12 47.9 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KSA01661.1 - 2.4e-08 34.0 0.1 6.1e-08 32.7 0.1 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 KSA01661.1 - 0.015 15.9 0.0 2.7 8.7 0.0 2.3 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain DUF4405 PF14358.6 KSA01661.1 - 5.3 7.7 14.4 4 8.1 3.3 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4405) Ada_Zn_binding PF02805.16 KSA01662.1 - 5.3e-18 64.8 2.3 1.2e-17 63.6 2.3 1.6 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_AraC PF00165.23 KSA01662.1 - 0.0011 19.0 0.0 0.0028 17.7 0.0 1.7 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.7 KSA01662.1 - 0.0014 18.9 0.0 0.0026 18.0 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain Pkinase PF00069.25 KSA01663.1 - 1.7e-68 230.8 0.0 2.3e-68 230.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KSA01663.1 - 5.4e-37 127.5 0.0 7.6e-37 127.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KSA01663.1 - 7.3e-06 25.5 0.0 0.00024 20.5 0.0 2.3 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KSA01663.1 - 0.00038 19.4 0.1 0.001 18.0 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 KSA01663.1 - 0.0049 16.2 0.0 0.01 15.2 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Aminotran_3 PF00202.21 KSA01664.1 - 1.5e-108 363.0 0.0 1.8e-108 362.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KSA01664.1 - 0.0002 20.7 0.0 0.0003 20.1 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Longin_2 PF18639.1 KSA01665.1 - 8.1e-12 45.3 1.8 7.2e-05 22.7 0.1 3.7 2 1 0 2 2 2 2 Yeast longin domain FNIP_N PF14636.6 KSA01665.1 - 0.00029 21.9 0.3 0.00029 21.9 0.3 6.0 4 2 2 6 6 6 2 Folliculin-interacting protein N-terminus SRI PF08236.11 KSA01666.1 - 1.4e-27 95.7 7.1 1.4e-27 95.7 7.1 2.8 2 0 0 2 2 2 1 SRI (Set2 Rpb1 interacting) domain SET PF00856.28 KSA01666.1 - 3.3e-18 66.6 0.5 3.3e-18 66.6 0.5 3.4 2 2 0 2 2 2 1 SET domain AWS PF17907.1 KSA01666.1 - 9e-15 54.4 11.4 9e-15 54.4 11.4 2.2 2 0 0 2 2 2 1 AWS domain WW PF00397.26 KSA01666.1 - 7.1e-07 29.2 1.0 7.1e-07 29.2 1.0 2.2 2 0 0 2 2 2 1 WW domain NAD_Gly3P_dh_C PF07479.14 KSA01667.1 - 9.7e-43 145.9 0.1 1.3e-42 145.5 0.1 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 KSA01667.1 - 5.7e-12 45.9 0.0 9.5e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Trigger_C PF05698.14 KSA01668.1 - 0.043 13.8 0.7 0.14 12.2 0.0 1.9 2 0 0 2 2 2 0 Bacterial trigger factor protein (TF) C-terminus DUF3445 PF11927.8 KSA01669.1 - 1.8e-61 207.6 0.4 2.1e-61 207.4 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Aminotran_3 PF00202.21 KSA01670.1 - 5.7e-61 206.4 0.0 6.9e-61 206.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 KSA01670.1 - 0.14 11.4 0.0 0.3 10.3 0.0 1.5 1 1 0 1 1 1 0 Beta-eliminating lyase Aldo_ket_red PF00248.21 KSA01671.1 - 1.1e-37 129.8 0.0 1.2e-35 123.2 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family ArsA_HSP20 PF17886.1 KSA01671.1 - 0.071 12.7 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 HSP20-like domain found in ArsA Fungal_trans_2 PF11951.8 KSA01672.1 - 1.3e-43 149.3 0.2 1.5e-43 149.0 0.2 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain ApbA_C PF08546.11 KSA01673.1 - 7.1e-29 100.5 0.1 2.4e-28 98.8 0.0 1.9 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 KSA01673.1 - 1.9e-22 79.5 0.1 3.1e-22 78.9 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Aa_trans PF01490.18 KSA01674.1 - 2.3e-18 66.1 34.8 3.6e-18 65.5 34.8 1.3 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KSA01674.1 - 0.0023 17.0 18.1 0.0023 17.0 18.1 3.0 1 1 1 3 3 3 1 Tryptophan/tyrosine permease family DUF2561 PF10812.8 KSA01674.1 - 0.058 13.4 0.2 0.058 13.4 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2561) Ank_5 PF13857.6 KSA01675.1 - 4.9e-33 112.8 4.9 4.6e-09 36.4 0.1 4.3 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 KSA01675.1 - 1.3e-32 112.2 0.3 5.6e-13 49.3 0.1 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KSA01675.1 - 1e-31 108.9 1.3 5.5e-09 36.4 0.0 5.0 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 KSA01675.1 - 8.3e-28 95.6 1.9 1.6e-08 34.6 0.0 5.5 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.6 KSA01675.1 - 1.7e-26 89.3 0.9 0.00024 21.3 0.0 6.2 6 0 0 6 6 6 5 Ankyrin repeat Abhydrolase_4 PF08386.10 KSA01675.1 - 0.12 12.5 0.1 4.2 7.5 0.0 2.7 2 1 1 3 3 3 0 TAP-like protein CLP1_P PF16575.5 KSA01676.1 - 1.5e-31 109.7 0.0 2.6e-31 108.9 0.0 1.4 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Clp1 PF06807.14 KSA01676.1 - 1.1e-26 93.5 0.0 2.1e-26 92.6 0.0 1.5 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 CLP1_N PF16573.5 KSA01676.1 - 1e-25 89.7 0.1 1.9e-25 88.9 0.1 1.5 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor AAA_16 PF13191.6 KSA01676.1 - 0.0042 17.5 0.0 0.0074 16.7 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain ATP_bind_1 PF03029.17 KSA01676.1 - 0.028 14.2 0.0 0.066 13.0 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein SRPRB PF09439.10 KSA01676.1 - 0.047 13.1 0.1 1.1 8.7 0.0 2.7 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit AAA_14 PF13173.6 KSA01676.1 - 0.055 13.5 0.0 0.19 11.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain OGG_N PF07934.12 KSA01676.1 - 0.069 13.2 0.1 0.67 10.0 0.0 2.3 2 1 1 3 3 3 0 8-oxoguanine DNA glycosylase, N-terminal domain PTPA PF03095.15 KSA01677.1 - 1.5e-114 382.6 0.2 1.7e-114 382.4 0.2 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein LETM1 PF07766.13 KSA01678.1 - 0.0012 18.3 3.5 0.049 13.0 0.1 2.9 3 0 0 3 3 3 2 LETM1-like protein MOZ_SAS PF01853.18 KSA01679.1 - 6.9e-78 260.4 0.3 1.8e-77 259.0 0.3 1.7 1 1 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.8 KSA01679.1 - 1.3e-22 79.5 0.1 2.4e-22 78.5 0.1 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain zf-MYST PF17772.1 KSA01679.1 - 5.6e-21 73.9 0.2 1.3e-20 72.7 0.2 1.7 1 0 0 1 1 1 1 MYST family zinc finger domain WD40 PF00400.32 KSA01680.1 - 3.5e-34 116.3 10.4 5.5e-06 27.0 0.1 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat Nucleoporin_N PF08801.11 KSA01680.1 - 1.4e-07 30.6 0.3 0.0037 16.1 0.0 3.2 2 1 0 3 3 3 2 Nup133 N terminal like ANAPC4_WD40 PF12894.7 KSA01680.1 - 0.00038 20.7 0.1 0.62 10.4 0.0 3.6 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KSA01680.1 - 0.0042 16.5 0.0 0.03 13.6 0.0 2.1 2 0 0 2 2 2 1 WD40-like domain PI3K_p85B PF02192.16 KSA01680.1 - 0.14 11.9 0.2 20 5.0 0.1 2.6 2 0 0 2 2 2 0 PI3-kinase family, p85-binding domain UQ_con PF00179.26 KSA01682.1 - 2e-38 131.2 0.8 2e-38 131.2 0.1 1.4 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme PT PF04886.12 KSA01683.1 - 8.3e-07 28.4 30.6 0.00014 21.3 7.1 9.4 6 3 1 7 7 7 4 PT repeat Glucosamine_iso PF01182.20 KSA01684.1 - 1.5e-52 178.7 0.0 2.2e-52 178.2 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase PI31_Prot_C PF08577.11 KSA01685.1 - 2.8e-11 44.4 10.2 2.8e-11 44.4 10.2 2.8 3 0 0 3 3 3 1 PI31 proteasome regulator ABC_membrane PF00664.23 KSA01686.1 - 1.2e-57 195.7 42.1 1.3e-41 143.1 14.1 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KSA01686.1 - 8.8e-47 159.1 0.6 8.1e-31 107.4 0.1 3.3 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KSA01686.1 - 1.1e-09 38.1 8.6 0.0039 16.7 1.7 4.5 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KSA01686.1 - 4.5e-07 29.5 0.1 0.0036 17.0 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KSA01686.1 - 6.7e-05 22.9 0.1 0.14 12.1 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase Vps51 PF08700.11 KSA01686.1 - 0.00019 21.4 3.4 0.18 11.9 0.4 3.0 2 0 0 2 2 2 2 Vps51/Vps67 AAA_21 PF13304.6 KSA01686.1 - 0.00021 21.2 14.8 0.57 9.9 0.1 5.4 5 1 1 6 6 6 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 KSA01686.1 - 0.00024 21.6 0.1 1 9.9 0.0 3.6 3 0 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.23 KSA01686.1 - 0.00034 20.7 1.1 0.21 11.6 0.1 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 KSA01686.1 - 0.0054 16.5 1.6 7.4 6.3 0.1 3.4 3 0 0 3 3 3 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 KSA01686.1 - 0.0077 16.6 0.0 0.59 10.5 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain T2SSE PF00437.20 KSA01686.1 - 0.012 14.7 0.0 0.25 10.4 0.1 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein Zeta_toxin PF06414.12 KSA01686.1 - 0.014 14.7 0.0 2.3 7.4 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_30 PF13604.6 KSA01686.1 - 0.027 14.2 0.2 11 5.7 0.0 2.7 3 0 0 3 3 3 0 AAA domain Dynamin_N PF00350.23 KSA01686.1 - 0.043 13.9 3.0 1.8 8.6 0.5 2.8 2 0 0 2 2 2 0 Dynamin family FtsK_SpoIIIE PF01580.18 KSA01686.1 - 0.074 12.4 0.5 22 4.3 0.0 3.2 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_23 PF13476.6 KSA01686.1 - 0.095 13.2 19.9 0.33 11.4 0.0 4.1 4 1 0 4 4 4 0 AAA domain ATP-synt_ab PF00006.25 KSA01686.1 - 0.099 12.3 0.0 3.7 7.2 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_27 PF13514.6 KSA01686.1 - 0.12 11.9 0.1 6.4 6.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KSA01686.1 - 0.15 12.3 7.6 4.4 7.6 0.1 3.9 3 1 0 3 3 3 0 AAA domain MeaB PF03308.16 KSA01686.1 - 0.22 10.5 0.2 11 4.8 0.0 2.4 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF87 PF01935.17 KSA01686.1 - 0.23 11.5 0.0 0.23 11.5 0.0 2.8 3 0 0 3 3 3 0 Helicase HerA, central domain cobW PF02492.19 KSA01686.1 - 0.24 11.0 0.9 1.4 8.5 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PRK PF00485.18 KSA01686.1 - 0.38 10.5 1.6 13 5.5 0.0 2.9 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family UCH PF00443.29 KSA01687.1 - 1.2e-51 175.8 6.0 2e-51 175.0 6.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KSA01687.1 - 7.4e-20 71.8 7.0 1.4e-19 70.8 7.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KSA01687.1 - 1.4e-11 44.5 15.5 1.4e-11 44.5 15.5 3.0 2 1 1 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein Phosducin PF02114.16 KSA01688.1 - 8.6e-13 47.8 1.2 8.6e-13 47.8 1.2 1.5 1 1 1 2 2 2 1 Phosducin BNIP2 PF12496.8 KSA01688.1 - 0.69 10.3 4.8 0.66 10.4 1.3 2.2 2 0 0 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Vma12 PF11712.8 KSA01688.1 - 0.76 9.8 4.0 12 5.9 4.0 2.2 1 1 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Cytochrom_C PF00034.21 KSA01689.1 - 3e-10 41.1 0.0 4.4e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 KSA01689.1 - 1.4e-07 31.7 1.4 1.6e-06 28.3 1.4 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 KSA01689.1 - 0.039 13.7 0.8 0.34 10.6 0.2 2.2 2 1 0 2 2 2 0 Cytochrome c-550 domain MA3 PF02847.17 KSA01690.1 - 5.4e-19 68.3 1.5 1.4e-18 66.9 1.5 1.8 1 0 0 1 1 1 1 MA3 domain RSRP PF17069.5 KSA01690.1 - 0.17 11.5 63.7 0.035 13.7 59.6 1.9 2 1 0 2 2 2 0 Arginine/Serine-Rich protein 1 PPR_2 PF13041.6 KSA01691.1 - 2.7e-14 53.1 0.0 1.4e-12 47.6 0.0 3.2 3 0 0 3 3 3 1 PPR repeat family PSII_Pbs31 PF18240.1 KSA01691.1 - 0.86 10.1 2.6 35 4.9 0.0 3.6 4 0 0 4 4 4 0 Photosystem II Psb31 protein CTP_transf_like PF01467.26 KSA01692.1 - 4.1e-07 30.3 0.1 8.4e-07 29.3 0.0 1.5 2 0 0 2 2 2 1 Cytidylyltransferase-like USP7_C2 PF14533.6 KSA01693.1 - 1.1e-61 208.1 7.7 1.3e-61 208.0 2.4 2.9 3 0 0 3 3 3 1 Ubiquitin-specific protease C-terminal UCH PF00443.29 KSA01693.1 - 1.3e-44 152.7 1.6 1.3e-44 152.7 1.6 2.6 2 1 1 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.8 KSA01693.1 - 7.5e-40 136.7 3.6 2.4e-38 131.8 2.4 3.1 2 1 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 UCH_1 PF13423.6 KSA01693.1 - 9.1e-20 71.5 0.2 7.5e-19 68.5 0.2 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Glutaredoxin2_C PF04399.13 KSA01693.1 - 0.11 12.4 0.1 23 4.8 0.0 2.8 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain Glyco_hydro_17 PF00332.18 KSA01694.1 - 2.3e-08 34.0 0.3 2.3e-08 34.0 0.3 1.7 2 1 0 2 2 2 1 Glycosyl hydrolases family 17 VanW PF04294.13 KSA01694.1 - 0.087 12.5 2.2 0.11 12.2 0.6 2.0 1 1 1 2 2 2 0 VanW like protein AF-4 PF05110.13 KSA01694.1 - 0.28 9.2 11.1 0.4 8.7 11.1 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Macoilin PF09726.9 KSA01694.1 - 0.56 8.7 4.3 0.64 8.5 4.3 1.1 1 0 0 1 1 1 0 Macoilin family DUF4653 PF15546.6 KSA01694.1 - 3.5 7.2 7.6 1.5 8.4 4.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4653) Rap1-DNA-bind PF09197.10 KSA01695.1 - 3.5e-38 130.5 9.3 2.5e-36 124.5 1.8 3.1 3 1 0 3 3 3 2 Rap1, DNA-binding Rap1_C PF11626.8 KSA01695.1 - 6.2e-14 51.8 0.0 1.5e-13 50.6 0.0 1.7 1 0 0 1 1 1 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain BRCT_2 PF16589.5 KSA01695.1 - 2.5e-09 37.4 0.3 1.2e-08 35.2 0.1 2.3 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain Myb_DNA-bind_2 PF08914.11 KSA01695.1 - 2.6e-06 27.5 4.5 0.00076 19.6 0.6 3.0 3 0 0 3 3 3 2 Rap1 Myb domain Myb_DNA-binding PF00249.31 KSA01695.1 - 0.17 12.1 0.1 0.48 10.7 0.1 1.8 1 0 0 1 1 1 0 Myb-like DNA-binding domain Metallophos PF00149.28 KSA01696.1 - 7.1e-12 46.3 1.0 1.2e-11 45.6 1.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KSA01696.1 - 3.9e-05 23.9 0.0 9.5e-05 22.6 0.0 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain FBPase_2 PF06874.11 KSA01696.1 - 0.087 11.1 0.3 0.15 10.3 0.3 1.3 1 0 0 1 1 1 0 Firmicute fructose-1,6-bisphosphatase RabGAP-TBC PF00566.18 KSA01697.1 - 2.1e-37 128.9 17.9 2.1e-32 112.5 8.5 2.4 2 0 0 2 2 2 2 Rab-GTPase-TBC domain PH_RBD PF12068.8 KSA01697.1 - 5.1e-05 22.8 0.1 0.00027 20.5 0.2 2.1 2 1 0 2 2 2 1 Rab-binding domain (RBD) SR-25 PF10500.9 KSA01697.1 - 0.06 13.0 0.0 0.06 13.0 0.0 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein rRNA_proc-arch PF13234.6 KSA01698.1 - 4.7e-83 279.2 1.3 4.7e-83 279.2 1.3 2.0 2 0 0 2 2 2 1 rRNA-processing arch domain DSHCT PF08148.12 KSA01698.1 - 1.6e-56 190.5 1.1 3.8e-56 189.3 1.1 1.7 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 KSA01698.1 - 1.3e-17 64.1 0.0 7.8e-17 61.6 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KSA01698.1 - 7.9e-07 29.4 0.0 3.5e-06 27.3 0.0 2.1 1 1 0 1 1 1 1 Helicase conserved C-terminal domain T2SSE PF00437.20 KSA01698.1 - 0.035 13.2 0.8 0.14 11.2 0.0 2.2 3 0 0 3 3 3 0 Type II/IV secretion system protein AAA_22 PF13401.6 KSA01698.1 - 0.042 14.1 0.0 0.18 12.1 0.0 2.1 1 0 0 1 1 1 0 AAA domain DUF4476 PF14771.6 KSA01698.1 - 0.06 13.6 0.8 0.27 11.5 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4476) ANAPC4_WD40 PF12894.7 KSA01700.1 - 0.00063 20.0 0.0 0.0041 17.4 0.0 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain DUF1132 PF06575.12 KSA01700.1 - 0.021 15.2 0.1 0.1 13.0 0.1 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1132) WD40 PF00400.32 KSA01700.1 - 0.25 12.3 1.8 2.2 9.3 0.0 3.4 5 0 0 5 5 5 0 WD domain, G-beta repeat Phos_pyr_kin PF08543.12 KSA01701.1 - 3.5e-10 39.7 0.0 5e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 KSA01701.1 - 0.00026 20.4 0.0 0.00055 19.3 0.0 1.5 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Carb_kinase PF01256.17 KSA01701.1 - 0.0066 16.0 0.0 0.034 13.6 0.0 1.9 1 1 1 2 2 2 1 Carbohydrate kinase Lipase_3 PF01764.25 KSA01702.1 - 1.6e-06 28.0 0.0 4e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KSA01702.1 - 0.0037 17.9 0.0 0.0065 17.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF3051 PF11252.8 KSA01702.1 - 0.054 13.2 0.0 0.09 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3051) PGAP1 PF07819.13 KSA01702.1 - 0.086 12.6 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein SUR7 PF06687.12 KSA01703.1 - 1.5e-38 132.6 15.2 1.7e-38 132.4 15.2 1.1 1 0 0 1 1 1 1 SUR7/PalI family TMEM43 PF07787.12 KSA01703.1 - 0.049 13.0 0.2 0.049 13.0 0.2 1.6 2 0 0 2 2 2 0 Transmembrane protein 43 DUF996 PF06195.13 KSA01703.1 - 0.47 10.7 10.8 0.14 12.4 6.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF996) Fig1 PF12351.8 KSA01703.1 - 0.85 9.5 16.3 0.11 12.4 11.0 1.9 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 Pkinase PF00069.25 KSA01704.1 - 3.3e-38 131.6 0.0 5e-38 131.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KSA01704.1 - 1.8e-19 70.0 0.0 3.3e-19 69.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KSA01704.1 - 8.8e-08 31.8 0.0 1.5e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 KSA01704.1 - 0.0028 17.3 0.2 0.069 12.8 0.1 2.3 1 1 1 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KSA01704.1 - 0.0046 16.3 0.0 0.008 15.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Nucleoporin_FG2 PF15967.5 KSA01704.1 - 0.016 13.8 1.3 0.023 13.3 1.3 1.1 1 0 0 1 1 1 0 Nucleoporin FG repeated region Ribosomal_L32e PF01655.18 KSA01705.1 - 4e-20 72.2 0.5 4.4e-20 72.1 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 Fmp27 PF10344.9 KSA01706.1 - 5.1e-178 594.0 47.7 1.3e-177 592.7 47.7 1.7 1 0 0 1 1 1 1 Mitochondrial protein from FMP27 Apt1 PF10351.9 KSA01706.1 - 1.8e-108 363.5 14.5 1.8e-108 363.5 14.5 2.6 2 0 0 2 2 2 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.9 KSA01706.1 - 1.9e-80 271.1 28.9 1e-45 156.6 5.3 3.3 3 1 1 4 4 4 2 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.9 KSA01706.1 - 3.3e-56 189.7 0.1 1.8e-55 187.3 0.0 2.3 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 KSA01706.1 - 7.1e-49 165.7 0.4 7.1e-49 165.7 0.4 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.9 KSA01706.1 - 2.6e-26 92.3 0.8 1.4e-25 89.9 0.1 2.8 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Rox3 PF08633.10 KSA01707.1 - 9.4e-19 68.5 0.4 6.9e-17 62.4 0.4 2.1 1 1 0 1 1 1 1 Rox3 mediator complex subunit RRM_1 PF00076.22 KSA01708.1 - 1.3e-10 40.9 0.0 2.8e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_2 PF13639.6 KSA01709.1 - 8.6e-11 42.0 5.8 1.4e-10 41.4 5.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KSA01709.1 - 2.9e-06 27.0 5.9 4.9e-06 26.3 5.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KSA01709.1 - 7e-06 25.7 0.3 1.3e-05 24.8 0.3 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 KSA01709.1 - 9.1e-05 22.7 6.5 0.00029 21.1 6.5 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KSA01709.1 - 0.00019 21.2 4.4 0.00035 20.4 4.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KSA01709.1 - 0.00046 20.2 2.2 0.00084 19.3 2.2 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 KSA01709.1 - 0.00051 20.0 4.1 0.00082 19.3 4.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KSA01709.1 - 0.00068 19.6 0.6 0.0021 18.0 0.2 2.1 1 1 1 2 2 2 1 RING-type zinc-finger Zf_RING PF16744.5 KSA01709.1 - 0.0012 18.9 2.4 0.0033 17.5 2.4 1.7 1 1 0 1 1 1 1 KIAA1045 RING finger zf-C3HC4_3 PF13920.6 KSA01709.1 - 0.064 13.1 4.0 0.1 12.5 4.0 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 KSA01709.1 - 0.075 12.9 5.4 0.15 12.0 5.4 1.5 1 0 0 1 1 1 0 PHD-finger Zn_ribbon_17 PF17120.5 KSA01709.1 - 0.079 12.6 3.6 0.16 11.7 3.6 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 KSA01709.1 - 0.18 11.6 6.3 0.34 10.7 6.3 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Herpes_UL49_5 PF05702.11 KSA01709.1 - 0.31 11.2 2.2 0.73 10.0 2.2 1.5 1 0 0 1 1 1 0 Herpesvirus UL49.5 envelope/tegument protein FANCL_C PF11793.8 KSA01709.1 - 0.37 11.0 3.2 1.2 9.4 3.2 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain Rad50_zn_hook PF04423.14 KSA01709.1 - 0.76 9.7 3.7 0.34 10.8 0.5 2.1 2 0 0 2 2 2 0 Rad50 zinc hook motif Prok-RING_4 PF14447.6 KSA01709.1 - 0.77 9.7 4.4 1.6 8.7 4.4 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 RINGv PF12906.7 KSA01709.1 - 0.94 9.7 6.0 1.9 8.7 6.0 1.6 1 0 0 1 1 1 0 RING-variant domain zf-RING-like PF08746.11 KSA01709.1 - 1 9.7 4.7 1.9 8.9 4.7 1.4 1 0 0 1 1 1 0 RING-like domain eIF-5a PF01287.20 KSA01710.1 - 1.1e-30 105.5 0.5 1.6e-30 105.0 0.5 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold PWWP PF00855.17 KSA01711.1 - 2.5e-21 75.9 0.2 9.2e-21 74.1 0.2 2.0 1 0 0 1 1 1 1 PWWP domain Med26 PF08711.11 KSA01711.1 - 2.3e-07 30.7 0.5 5.6e-07 29.5 0.5 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Corazonin PF17308.2 KSA01711.1 - 0.23 11.8 0.2 0.23 11.8 0.2 3.2 2 2 0 2 2 2 0 Pro-corazonin SpoIIIAH PF12685.7 KSA01713.1 - 0.01 15.7 2.0 1.7 8.4 0.0 2.1 2 0 0 2 2 2 0 SpoIIIAH-like protein RNA_pol_3_Rpc31 PF11705.8 KSA01713.1 - 0.13 12.6 10.6 0.17 12.1 10.6 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DNA_pol_phi PF04931.13 KSA01713.1 - 0.2 9.7 6.9 0.27 9.3 6.9 1.2 1 0 0 1 1 1 0 DNA polymerase phi CENP-B_dimeris PF09026.10 KSA01713.1 - 1.3 9.4 8.7 2.7 8.5 8.7 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 KSA01713.1 - 1.5 8.0 6.1 2.1 7.6 6.1 1.1 1 0 0 1 1 1 0 NOA36 protein SDA1 PF05285.12 KSA01713.1 - 3.2 7.1 9.0 4.4 6.6 9.0 1.1 1 0 0 1 1 1 0 SDA1 DNApol_Exo PF18136.1 KSA01714.1 - 2.1e-86 289.6 0.1 4.5e-86 288.5 0.1 1.6 1 0 0 1 1 1 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 KSA01714.1 - 1.4e-56 192.2 0.3 8.7e-56 189.6 0.1 2.3 2 0 0 2 2 2 1 DNA polymerase family A MFS_1 PF07690.16 KSA01715.1 - 2.9e-31 108.7 29.0 8.3e-28 97.3 13.2 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KSA01715.1 - 2.5e-07 29.9 6.2 2.5e-07 29.9 6.2 2.0 2 1 0 2 2 2 1 Sugar (and other) transporter UNC-93 PF05978.16 KSA01715.1 - 9.5e-05 22.2 2.6 9.5e-05 22.2 2.6 2.4 2 1 1 3 3 3 1 Ion channel regulatory protein UNC-93 DUF4064 PF13273.6 KSA01715.1 - 0.17 12.2 4.1 5.6 7.3 0.6 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF4064) DUF4588 PF15251.6 KSA01715.1 - 0.22 11.3 0.6 0.31 10.8 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) Cytochrom_B_C PF00032.17 KSA01715.1 - 1.3 9.4 5.2 0.55 10.5 0.2 2.8 3 1 1 4 4 4 0 Cytochrome b(C-terminal)/b6/petD Syntaxin_2 PF14523.6 KSA01716.1 - 0.017 15.5 0.2 0.043 14.2 0.2 1.7 1 0 0 1 1 1 0 Syntaxin-like protein BLOC1_2 PF10046.9 KSA01718.1 - 1.9 8.8 9.7 0.19 12.0 0.7 3.0 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Trypsin_2 PF13365.6 KSA01719.1 - 4.4e-11 43.9 0.0 6.5e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 KSA01719.1 - 0.00059 19.7 0.0 0.001 19.0 0.0 1.3 1 0 0 1 1 1 1 Trypsin zf-BED PF02892.15 KSA01720.1 - 2.3e-06 27.5 0.1 6.1e-06 26.2 0.1 1.7 1 0 0 1 1 1 1 BED zinc finger PyrI_C PF02748.15 KSA01720.1 - 0.046 13.6 0.0 0.089 12.7 0.0 1.4 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Arc_trans_TRASH PF08394.10 KSA01720.1 - 0.09 13.1 0.7 0.18 12.1 0.7 1.5 1 0 0 1 1 1 0 Archaeal TRASH domain PepSY_TM PF03929.16 KSA01720.1 - 1.2 8.7 4.4 1.1 8.9 2.7 1.7 2 0 0 2 2 2 0 PepSY-associated TM region Ribosomal_L44 PF00935.19 KSA01722.1 - 3.4e-36 123.5 12.7 5.3e-36 123.0 12.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 Pkinase PF00069.25 KSA01723.1 - 9.5e-58 195.6 0.5 1.1e-41 143.0 0.3 3.1 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 KSA01723.1 - 1.8e-24 86.4 0.3 1e-20 74.1 0.0 3.0 2 1 2 4 4 4 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KSA01723.1 - 0.46 9.2 11.7 0.29 9.9 0.1 2.4 2 0 0 2 2 2 0 Fungal protein kinase APH PF01636.23 KSA01723.1 - 0.93 9.4 11.4 0.92 9.4 0.2 3.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family Ytp1 PF10355.9 KSA01724.1 - 2.5e-107 358.2 7.3 4.2e-107 357.5 7.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 KSA01724.1 - 5.3e-34 116.2 8.2 5.3e-34 116.2 8.2 2.8 3 1 1 4 4 4 1 Domain of unknown function (DUF2427) MIF4G_like PF09088.11 KSA01725.1 - 2.5e-56 190.5 1.3 4.9e-56 189.5 1.3 1.5 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.11 KSA01725.1 - 3.2e-47 161.3 16.1 3.6e-46 157.8 7.3 3.3 2 1 0 2 2 2 2 MIF4G like ApoB100_C PF12491.8 KSA01725.1 - 2.7 8.0 6.6 10 6.2 0.0 4.2 4 0 0 4 4 4 0 Apolipoprotein B100 C terminal ABC_tran PF00005.27 KSA01726.1 - 3.3e-15 56.8 0.1 1.2e-14 55.0 0.1 1.9 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KSA01726.1 - 1.3e-07 31.8 3.5 0.0017 18.3 1.8 2.6 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KSA01726.1 - 0.00064 19.7 0.1 0.0014 18.6 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 KSA01726.1 - 0.0016 18.1 0.1 0.0034 17.1 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 KSA01726.1 - 0.0024 18.4 4.2 0.011 16.3 0.2 2.2 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 KSA01726.1 - 0.0025 17.3 0.1 2.3 7.6 0.0 2.5 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 KSA01726.1 - 0.0066 16.2 1.5 0.04 13.6 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 KSA01726.1 - 0.015 15.8 0.4 0.062 13.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KSA01726.1 - 0.022 14.7 0.0 0.043 13.7 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_25 PF13481.6 KSA01726.1 - 0.041 13.5 0.4 0.56 9.7 0.1 2.2 1 1 1 2 2 2 0 AAA domain Flexi_CP PF00286.20 KSA01726.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Viral coat protein AAA PF00004.29 KSA01726.1 - 0.12 12.8 0.9 1.1 9.7 0.1 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ORC6 PF05460.13 KSA01727.1 - 0.032 13.5 0.1 0.035 13.4 0.1 1.0 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) NDK PF00334.19 KSA01728.1 - 9.8e-53 177.8 0.0 1.1e-52 177.6 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase WD40 PF00400.32 KSA01729.1 - 3.4e-15 56.2 9.0 0.055 14.4 0.0 7.5 8 0 0 8 8 8 4 WD domain, G-beta repeat YL1 PF05764.13 KSA01729.1 - 5 7.2 55.3 14 5.7 0.1 2.5 2 0 0 2 2 2 0 YL1 nuclear protein RabGAP-TBC PF00566.18 KSA01730.1 - 9.1e-17 61.4 8.4 9.1e-17 61.4 8.4 2.0 2 0 0 2 2 2 1 Rab-GTPase-TBC domain TauD PF02668.16 KSA01731.1 - 3.7e-40 138.4 0.0 5.1e-40 138.0 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 KSA01731.1 - 1.3e-16 61.0 3.2 1.4e-16 60.9 0.7 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF971) Aldo_ket_red PF00248.21 KSA01732.1 - 2.1e-49 168.3 0.0 2.7e-49 167.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family T2SSE PF00437.20 KSA01733.1 - 0.0024 17.0 1.3 0.0032 16.6 0.0 1.8 2 0 0 2 2 2 1 Type II/IV secretion system protein RsgA_GTPase PF03193.16 KSA01733.1 - 0.0049 16.8 0.9 0.011 15.6 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_14 PF13173.6 KSA01733.1 - 0.011 15.7 1.1 0.21 11.6 0.1 3.2 1 1 1 2 2 2 0 AAA domain AAA_7 PF12775.7 KSA01733.1 - 0.012 15.2 0.0 0.031 13.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 KSA01733.1 - 0.018 15.3 1.2 0.036 14.3 0.1 2.1 2 1 0 2 2 2 0 AAA domain Mt_ATP-synt_D PF05873.12 KSA01733.1 - 0.021 14.7 6.8 0.048 13.5 4.7 2.4 2 0 0 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) AAA_19 PF13245.6 KSA01733.1 - 0.057 13.8 0.4 0.16 12.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KSA01733.1 - 0.12 12.9 0.0 0.12 12.9 0.0 2.7 2 1 0 2 2 2 0 ABC transporter AAA PF00004.29 KSA01733.1 - 0.12 12.8 0.0 0.12 12.8 0.0 2.8 2 1 1 3 3 3 0 ATPase family associated with various cellular activities (AAA) TMF_TATA_bd PF12325.8 KSA01733.1 - 2.9 8.1 21.1 0.45 10.7 0.6 2.9 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DivIC PF04977.15 KSA01733.1 - 3.3 7.5 22.7 4.7 7.1 6.0 4.8 4 1 1 5 5 5 0 Septum formation initiator HALZ PF02183.18 KSA01733.1 - 9.4 6.6 13.3 8.7 6.7 0.5 4.0 3 0 0 3 3 3 0 Homeobox associated leucine zipper MOR2-PAG1_mid PF14228.6 KSA01734.1 - 2.4e-17 61.9 5.7 7.2e-09 33.9 2.1 4.2 3 2 0 3 3 3 3 Cell morphogenesis central region DUF3730 PF12530.8 KSA01734.1 - 0.0026 17.4 0.0 0.0063 16.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3730) ELMO_CED12 PF04727.13 KSA01734.1 - 0.11 12.6 3.8 0.084 13.0 0.7 2.3 2 1 0 2 2 2 0 ELMO/CED-12 family MOR2-PAG1_N PF14222.6 KSA01735.1 - 3.1e-138 462.1 8.6 4.6e-138 461.6 8.6 1.2 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MMS19_C PF12460.8 KSA01736.1 - 1.9e-97 327.1 26.4 1.9e-97 327.1 26.4 4.0 4 1 1 5 5 5 1 RNAPII transcription regulator C-terminal MMS19_N PF14500.6 KSA01736.1 - 7.5e-78 261.7 4.3 7.5e-78 261.7 4.3 3.8 4 1 1 5 5 5 2 Dos2-interacting transcription regulator of RNA-Pol-II Ipi1_N PF12333.8 KSA01736.1 - 0.033 14.8 5.8 0.31 11.6 0.0 4.3 4 1 0 4 4 4 0 Rix1 complex component involved in 60S ribosome maturation HEAT_EZ PF13513.6 KSA01736.1 - 0.12 13.0 0.9 1.2e+02 3.3 0.0 4.8 5 1 1 6 6 6 0 HEAT-like repeat DASH_Hsk3 PF08227.11 KSA01736.1 - 0.64 10.4 3.0 0.88 10.0 0.1 2.9 3 0 0 3 3 3 0 DASH complex subunit Hsk3 like RRT14 PF17075.5 KSA01737.1 - 1e-66 224.8 23.2 1.2e-66 224.7 23.2 1.0 1 0 0 1 1 1 1 Regular of rDNA transcription protein 14 NPL4 PF05021.15 KSA01737.1 - 0.04 13.3 1.8 0.056 12.8 1.8 1.3 1 0 0 1 1 1 0 NPL4 family PAP_central PF04928.17 KSA01737.1 - 0.32 9.9 4.8 0.43 9.5 4.8 1.2 1 0 0 1 1 1 0 Poly(A) polymerase central domain Fasciclin PF02469.22 KSA01737.1 - 9.8 6.4 8.8 14 5.9 8.0 1.8 1 1 0 1 1 1 0 Fasciclin domain SCP2 PF02036.17 KSA01738.1 - 2.9e-23 82.3 5.3 3.3e-23 82.1 5.3 1.0 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 KSA01738.1 - 3.3e-05 24.2 0.4 4.2e-05 23.8 0.4 1.2 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Phage_CI_C PF16452.5 KSA01738.1 - 0.046 14.0 0.2 0.089 13.1 0.1 1.5 2 0 0 2 2 2 0 Bacteriophage CI repressor C-terminal domain WD40 PF00400.32 KSA01739.1 - 2.2e-10 40.9 0.1 1.4 9.9 0.0 5.6 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KSA01739.1 - 7.5e-08 32.6 0.7 0.17 12.2 0.0 4.8 1 1 5 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain BBS2_N PF14781.6 KSA01739.1 - 0.1 12.5 0.4 3.9 7.4 0.1 2.8 2 1 0 2 2 2 0 Ciliary BBSome complex subunit 2, N-terminal Apolipoprotein PF01442.18 KSA01740.1 - 0.011 15.7 0.7 1.5 8.6 0.0 2.6 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain CCDC-167 PF15188.6 KSA01740.1 - 0.058 13.7 4.8 0.095 13.1 1.4 2.6 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 TBCC_N PF16752.5 KSA01740.1 - 0.16 12.4 6.8 0.89 10.0 0.1 2.7 2 1 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain Baculo_PEP_C PF04513.12 KSA01740.1 - 0.45 10.6 38.2 0.17 11.9 15.1 3.0 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus FliJ PF02050.16 KSA01740.1 - 0.55 10.5 3.2 2.8 8.2 0.4 2.8 1 1 1 2 2 2 0 Flagellar FliJ protein DLP_helical PF18709.1 KSA01740.1 - 0.74 9.0 8.7 2.8 7.1 1.4 2.9 1 1 1 3 3 3 0 Dynamin-like helical domain MitMem_reg PF13012.6 KSA01740.1 - 2.7 8.4 11.9 1.8e+02 2.6 11.9 2.7 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function Cation_ATPase_C PF00689.21 KSA01741.1 - 4.2e-42 143.9 5.4 4.2e-42 143.9 5.4 2.0 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KSA01741.1 - 1e-37 129.4 0.2 1e-37 129.4 0.2 2.5 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 KSA01741.1 - 2.7e-21 75.4 0.0 6.2e-21 74.3 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KSA01741.1 - 3.6e-14 53.5 2.4 3.5e-11 43.8 0.2 2.6 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KSA01741.1 - 3.3e-10 39.5 0.0 1.1e-09 37.8 0.0 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KSA01741.1 - 0.0015 18.4 0.1 0.0043 16.8 0.1 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase NYN_YacP PF05991.11 KSA01741.1 - 0.13 12.2 0.1 0.48 10.3 0.0 2.0 2 0 0 2 2 2 0 YacP-like NYN domain Rav1p_C PF12234.8 KSA01743.1 - 1.3e-237 790.3 10.8 1.3e-237 790.3 10.8 2.6 2 1 1 3 3 3 2 RAVE protein 1 C terminal Pet191_N PF10203.9 KSA01744.1 - 6.9e-23 80.7 4.4 9.6e-23 80.3 4.4 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 zf-C2H2_9 PF16293.5 KSA01744.1 - 0.0045 16.8 0.1 0.064 13.1 0.1 2.3 2 0 0 2 2 2 1 C2H2 type zinc-finger (1 copy) CX9C PF16860.5 KSA01744.1 - 1.1 9.4 5.0 1.2 9.2 0.8 2.5 1 1 1 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Pyridoxal_deC PF00282.19 KSA01745.1 - 1e-64 218.6 0.0 1.3e-64 218.3 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KSA01745.1 - 0.00077 18.5 0.0 0.0012 17.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KSA01745.1 - 0.017 14.4 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase DHDPS PF00701.22 KSA01745.1 - 0.045 12.4 0.0 0.088 11.5 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate synthetase family MFS_1 PF07690.16 KSA01746.1 - 2.3e-08 33.4 28.4 4.1e-08 32.5 28.4 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 KSA01746.1 - 2.2e-07 30.7 8.7 2.2e-07 30.7 8.7 2.5 2 1 0 2 2 2 1 Ion channel regulatory protein UNC-93 CPSF_A PF03178.15 KSA01747.1 - 8.4e-99 330.9 0.5 3.7e-98 328.8 0.3 2.2 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.9 KSA01747.1 - 2.3e-98 330.0 4.5 2.3e-98 330.0 4.5 2.3 3 0 0 3 3 3 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Forkhead PF00250.18 KSA01748.1 - 1.7e-35 121.2 0.9 4.3e-35 119.8 0.9 1.7 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 KSA01748.1 - 5.6e-09 36.2 0.1 2.5e-08 34.1 0.0 2.2 2 0 0 2 2 2 1 FHA domain Linker_histone PF00538.19 KSA01748.1 - 0.015 15.6 0.1 0.058 13.8 0.1 2.0 1 0 0 1 1 1 0 linker histone H1 and H5 family FHA_2 PF17913.1 KSA01748.1 - 0.039 14.2 0.0 0.094 13.0 0.0 1.6 1 0 0 1 1 1 0 FHA domain Extensin_2 PF04554.13 KSA01748.1 - 1.4 9.1 27.3 0.63 10.2 18.8 2.9 2 0 0 2 2 2 0 Extensin-like region WD40 PF00400.32 KSA01749.1 - 2.3e-10 40.9 12.4 0.0014 19.4 1.9 5.8 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KSA01749.1 - 5e-08 33.1 0.5 0.03 14.6 0.0 4.3 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KSA01749.1 - 0.0034 17.3 1.4 1.6 8.5 0.0 3.0 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A RecO_N_2 PF13114.6 KSA01749.1 - 0.054 13.2 1.1 0.23 11.2 0.2 2.5 2 0 0 2 2 2 0 RecO N terminal EMP24_GP25L PF01105.24 KSA01750.1 - 7.1e-49 166.2 0.5 8.5e-49 166.0 0.5 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Sec34 PF04136.15 KSA01750.1 - 0.01 15.7 0.5 0.018 14.9 0.5 1.3 1 0 0 1 1 1 0 Sec34-like family SdrD_B PF17210.3 KSA01750.1 - 0.032 14.4 0.0 0.07 13.4 0.0 1.4 1 1 0 1 1 1 0 SdrD B-like domain KRAP_IP3R_bind PF14722.6 KSA01750.1 - 0.066 13.0 0.0 0.3 10.8 0.0 1.9 2 0 0 2 2 2 0 Ki-ras-induced actin-interacting protein-IP3R-interacting domain Vps8 PF12816.7 KSA01751.1 - 2.6e-58 196.8 4.7 5.8e-58 195.7 4.7 1.7 1 0 0 1 1 1 1 Golgi CORVET complex core vacuolar protein 8 DUF842 PF05811.13 KSA01751.1 - 0.0065 16.2 0.7 0.015 15.0 0.7 1.6 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) Vps39_1 PF10366.9 KSA01751.1 - 0.045 14.0 1.9 1.4 9.2 0.1 3.2 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 zf-C3HC4 PF00097.25 KSA01751.1 - 0.054 13.4 1.4 0.19 11.6 1.4 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KSA01751.1 - 0.065 13.6 0.8 0.3 11.4 0.8 2.2 1 0 0 1 1 1 0 Ring finger domain zf-rbx1 PF12678.7 KSA01751.1 - 0.07 13.4 0.4 0.2 12.0 0.4 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_11 PF17123.5 KSA01751.1 - 0.11 12.3 0.7 0.36 10.6 0.7 1.9 1 0 0 1 1 1 0 RING-like zinc finger WD40 PF00400.32 KSA01751.1 - 7.3 7.6 5.6 24 6.0 0.0 4.1 4 0 0 4 4 4 0 WD domain, G-beta repeat Chitin_synth_1 PF01644.17 KSA01752.1 - 1.1e-65 220.5 0.2 1.9e-65 219.8 0.2 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KSA01752.1 - 1.2e-25 89.3 0.0 2.6e-25 88.2 0.0 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KSA01752.1 - 2.6e-24 85.8 0.1 4.1e-19 68.6 0.0 2.6 3 0 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KSA01752.1 - 3.2e-13 50.0 2.2 2.3e-12 47.3 2.2 2.4 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 KSA01752.1 - 0.0029 17.1 0.0 0.073 12.5 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 KSA01752.1 - 0.0049 16.8 0.0 0.014 15.3 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 DUF2189 PF09955.9 KSA01752.1 - 0.005 17.1 0.2 0.005 17.1 0.2 3.5 2 1 0 3 3 3 1 Predicted integral membrane protein (DUF2189) Baculo_11_kDa PF06143.11 KSA01752.1 - 0.027 14.0 1.2 0.1 12.2 1.2 1.9 1 0 0 1 1 1 0 Baculovirus 11 kDa family Glycos_transf_2 PF00535.26 KSA01752.1 - 0.082 12.7 0.0 6.5 6.5 0.0 2.5 2 0 0 2 2 2 0 Glycosyl transferase family 2 TMEMspv1-c74-12 PF11044.8 KSA01752.1 - 0.77 9.8 3.2 5.3 7.1 0.7 2.8 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein STG PF15809.5 KSA01753.1 - 0.13 12.4 3.0 0.12 12.4 3.0 1.1 1 0 0 1 1 1 0 Simian taste bud-specific gene product family E1-E2_ATPase PF00122.20 KSA01754.1 - 6.8e-45 152.8 4.3 3.9e-44 150.3 4.0 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 KSA01754.1 - 4.7e-19 69.5 0.1 1.2e-18 68.2 0.1 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KSA01754.1 - 4.1e-11 42.4 0.0 8.7e-11 41.4 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KSA01754.1 - 0.0032 17.2 0.1 0.0032 17.2 0.1 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2818 PF10993.8 KSA01754.1 - 0.17 12.5 1.9 0.33 11.5 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2818) DUF2613 PF11021.8 KSA01754.1 - 0.77 9.9 7.5 2 8.6 0.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) PUF PF00806.19 KSA01755.1 - 8.7e-62 201.5 6.8 3.1e-08 32.8 0.0 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat ERG4_ERG24 PF01222.17 KSA01756.1 - 1.2e-160 535.0 26.0 1.4e-160 534.8 26.0 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Proteasome PF00227.26 KSA01757.1 - 5.5e-47 159.7 0.0 7.5e-47 159.3 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KSA01757.1 - 1.5e-14 53.3 0.5 2.8e-14 52.4 0.1 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Hist_deacetyl PF00850.19 KSA01758.1 - 2.3e-82 276.9 0.0 3.1e-82 276.5 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Pkinase PF00069.25 KSA01759.1 - 2.9e-56 190.8 3.1 4.8e-56 190.0 3.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KSA01759.1 - 1.2e-35 123.0 0.2 2.3e-35 122.1 0.2 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KSA01759.1 - 1.9e-05 23.7 0.1 1.9e-05 23.7 0.1 2.0 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 KSA01759.1 - 0.0018 17.7 0.0 0.0033 16.8 0.0 1.5 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KSA01759.1 - 0.069 12.7 0.4 0.3 10.7 0.4 2.0 2 0 0 2 2 2 0 RIO1 family Rhodanese PF00581.20 KSA01760.1 - 1.5e-11 44.7 0.1 5e-11 43.1 0.1 1.9 1 0 0 1 1 1 1 Rhodanese-like domain DUF916 PF06030.12 KSA01760.1 - 0.51 10.4 8.3 0.16 12.0 1.8 3.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF916) adh_short PF00106.25 KSA01761.1 - 2.6e-86 288.1 8.0 7.4e-47 159.3 0.6 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KSA01761.1 - 6.3e-71 238.6 6.8 6.3e-40 137.2 0.7 3.4 2 2 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase MaoC_dehydratas PF01575.19 KSA01761.1 - 2e-33 114.6 0.0 5e-33 113.3 0.0 1.7 1 0 0 1 1 1 1 MaoC like domain KR PF08659.10 KSA01761.1 - 1e-32 113.5 3.8 2.2e-16 60.3 0.2 2.2 2 0 0 2 2 2 2 KR domain Glucokinase PF02685.16 KSA01761.1 - 0.0084 15.1 0.1 0.38 9.7 0.0 2.4 2 0 0 2 2 2 1 Glucokinase GCIP PF13324.6 KSA01761.1 - 0.18 11.4 5.3 0.33 10.5 5.3 1.3 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting PglL_A PF15864.5 KSA01761.1 - 0.22 11.3 4.6 4.9 7.0 0.3 2.5 2 0 0 2 2 2 0 Protein glycosylation ligase Sporozoite_P67 PF05642.11 KSA01761.1 - 0.81 7.7 3.9 1.3 7.0 3.9 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DNA_pol_phi PF04931.13 KSA01761.1 - 2.5 6.1 8.7 4.2 5.4 8.7 1.2 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 KSA01761.1 - 4.6 6.5 12.3 7.2 5.8 12.3 1.2 1 0 0 1 1 1 0 NOA36 protein RXT2_N PF08595.11 KSA01761.1 - 4.6 7.2 5.9 10 6.2 5.9 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal Acyltransferase PF01553.21 KSA01762.1 - 6e-10 38.9 0.0 6.8e-06 25.7 0.0 2.4 2 0 0 2 2 2 2 Acyltransferase DUF3074 PF11274.8 KSA01763.1 - 1.5e-32 113.1 0.0 2.2e-32 112.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) TelA PF05816.11 KSA01763.1 - 0.067 12.3 1.6 0.09 11.8 1.6 1.1 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) AAA PF00004.29 KSA01765.1 - 1.1e-09 38.7 0.9 9.4e-09 35.8 0.0 2.7 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KSA01765.1 - 1.4e-07 31.6 0.3 1.9e-06 27.9 0.3 2.6 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 KSA01765.1 - 1.3e-05 25.5 0.0 5.4e-05 23.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KSA01765.1 - 0.00011 22.8 0.1 0.0015 19.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KSA01765.1 - 0.0003 20.8 0.0 0.0012 18.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 KSA01765.1 - 0.0014 18.7 0.1 0.0014 18.7 0.1 2.8 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 KSA01765.1 - 0.0062 16.9 0.0 0.053 13.9 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain TsaE PF02367.17 KSA01765.1 - 0.011 15.7 0.0 0.023 14.7 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RuvB_N PF05496.12 KSA01765.1 - 0.013 15.3 0.0 0.029 14.1 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KSA01765.1 - 0.098 12.8 0.5 0.25 11.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_6 PF12774.7 KSA01765.1 - 0.18 10.7 0.9 0.38 9.7 0.0 2.0 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region CRAL_TRIO PF00650.20 KSA01766.1 - 2.4e-35 121.6 0.0 3.5e-35 121.1 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KSA01766.1 - 1.6e-08 34.6 0.9 4.2e-08 33.3 0.9 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KSA01766.1 - 0.012 15.8 0.0 0.021 14.9 0.0 1.5 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain DUF1769 PF08588.10 KSA01766.1 - 0.098 12.9 0.1 0.29 11.4 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1769) RasGAP PF00616.19 KSA01767.1 - 5.5e-61 205.9 5.0 5.5e-61 205.9 5.0 2.5 4 0 0 4 4 4 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 KSA01767.1 - 7.8e-05 22.9 0.0 0.00028 21.1 0.0 2.0 2 0 0 2 2 2 1 C2 domain UPF1_Zn_bind PF09416.10 KSA01768.1 - 9.4e-65 217.2 13.8 1.1e-64 217.1 10.7 2.4 3 0 0 3 3 3 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.6 KSA01768.1 - 1.1e-57 194.9 0.0 2.1e-57 194.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KSA01768.1 - 8.1e-52 176.6 3.3 9.8e-31 107.5 0.5 2.3 1 1 1 2 2 2 2 AAA domain DUF5599 PF18141.1 KSA01768.1 - 4.2e-29 100.6 0.0 1.1e-28 99.3 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 KSA01768.1 - 1.5e-15 57.5 0.1 1.7e-14 54.0 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KSA01768.1 - 7.4e-13 49.1 0.0 1.6e-12 48.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KSA01768.1 - 1.8e-06 27.9 0.8 0.028 14.2 0.0 3.5 4 0 0 4 4 4 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 KSA01768.1 - 4.3e-06 26.2 0.2 0.00094 18.5 0.0 3.3 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 KSA01768.1 - 1.4e-05 25.1 0.0 3.1e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Ribosomal_S13_N PF08069.12 KSA01768.1 - 0.00087 19.3 0.0 0.0022 18.0 0.0 1.7 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain UvrD-helicase PF00580.21 KSA01768.1 - 0.00093 18.8 0.1 0.09 12.3 0.1 2.5 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.14 KSA01768.1 - 0.0026 17.6 0.0 0.006 16.5 0.0 1.6 1 0 0 1 1 1 1 Helicase AAA_10 PF12846.7 KSA01768.1 - 0.011 14.6 0.2 0.03 13.3 0.0 1.7 2 1 0 2 2 2 0 AAA-like domain PIF1 PF05970.14 KSA01768.1 - 0.014 14.6 0.1 4.5 6.3 0.0 2.5 2 0 0 2 2 2 0 PIF1-like helicase PhoH PF02562.16 KSA01768.1 - 0.023 14.2 0.0 0.052 13.0 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_22 PF13401.6 KSA01768.1 - 0.024 14.9 0.0 0.32 11.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain DEAD PF00270.29 KSA01768.1 - 0.094 12.5 0.1 0.21 11.3 0.1 1.7 1 1 0 1 1 1 0 DEAD/DEAH box helicase T2SSE PF00437.20 KSA01768.1 - 0.11 11.5 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Mg_chelatase PF01078.21 KSA01768.1 - 0.12 11.7 0.1 0.41 10.0 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI SCHIP-1 PF10148.9 KSA01770.1 - 9.9 5.7 9.1 1.5 8.3 2.7 2.2 2 0 0 2 2 2 0 Schwannomin-interacting protein 1 UQ_con PF00179.26 KSA01772.1 - 9.8e-47 158.1 0.0 1.1e-46 158.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KSA01772.1 - 0.0055 16.4 0.0 0.0072 16.0 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 KSA01772.1 - 0.068 13.0 0.1 0.13 12.1 0.1 1.5 1 1 0 1 1 1 0 UEV domain PhoLip_ATPase_C PF16212.5 KSA01773.1 - 6.7e-76 255.3 30.2 6.7e-76 255.3 30.2 2.3 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KSA01773.1 - 8.5e-16 57.4 0.4 3.2e-15 55.5 0.4 2.0 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 KSA01773.1 - 6.9e-12 45.3 0.0 4.3e-11 42.7 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KSA01773.1 - 1.8e-09 38.2 3.2 9e-05 22.8 0.7 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KSA01773.1 - 3.9e-05 23.2 0.1 0.00099 18.7 0.0 2.7 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KSA01773.1 - 0.0035 17.1 0.1 0.0035 17.1 0.1 3.4 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Mito_carr PF00153.27 KSA01774.1 - 6.1e-68 224.8 5.2 5.4e-25 87.2 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein ACAS_N PF16177.5 KSA01774.1 - 0.35 10.8 2.8 0.7 9.9 2.8 1.5 1 0 0 1 1 1 0 Acetyl-coenzyme A synthetase N-terminus SAM_decarbox PF01536.16 KSA01775.1 - 2e-136 454.7 5.2 2.3e-136 454.5 5.2 1.0 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase Dynamin_M PF01031.20 KSA01776.1 - 1.6e-98 329.5 0.1 2.8e-98 328.6 0.1 1.4 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 KSA01776.1 - 3.4e-56 189.9 0.1 6.8e-56 188.9 0.1 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 KSA01776.1 - 4.8e-30 103.6 5.1 4.9e-30 103.5 3.4 1.9 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KSA01776.1 - 0.0001 22.4 0.2 0.0004 20.4 0.2 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase Sda PF08970.10 KSA01776.1 - 0.13 12.1 0.3 0.52 10.1 0.0 2.2 2 0 0 2 2 2 0 Sporulation inhibitor A Pkinase PF00069.25 KSA01777.1 - 7.5e-67 225.5 0.0 1e-66 225.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KSA01777.1 - 1.4e-38 132.7 0.0 1.9e-38 132.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KSA01777.1 - 2.4e-07 30.4 0.0 5e-07 29.3 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KSA01777.1 - 3e-05 23.0 0.0 6.9e-05 21.8 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Pkinase_C PF00433.24 KSA01777.1 - 0.00019 22.1 1.2 0.0013 19.4 0.8 2.4 2 1 0 2 2 2 1 Protein kinase C terminal domain FTA2 PF13095.6 KSA01777.1 - 0.075 12.6 0.0 0.52 9.9 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Macro PF01661.21 KSA01778.1 - 4.8e-28 97.6 0.0 5.7e-28 97.3 0.0 1.1 1 0 0 1 1 1 1 Macro domain HTH_5 PF01022.20 KSA01778.1 - 0.11 12.4 0.1 0.18 11.7 0.1 1.3 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 KSA01778.1 - 0.12 12.4 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain TruB_N PF01509.18 KSA01780.1 - 6.1e-44 150.0 0.0 3.1e-43 147.7 0.1 1.9 2 0 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 KSA01780.1 - 0.0059 16.7 0.0 0.011 15.9 0.0 1.4 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain RRN3 PF05327.11 KSA01780.1 - 0.37 9.3 4.1 0.51 8.8 4.1 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Erf4 PF10256.9 KSA01781.1 - 7.3e-34 116.4 0.2 9.9e-34 115.9 0.2 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family VPS53_C PF16854.5 KSA01781.1 - 0.11 12.3 0.3 0.11 12.3 0.3 1.7 2 0 0 2 2 2 0 Vacuolar protein sorting-associated protein 53 C-terminus ANAPC4 PF12896.7 KSA01781.1 - 0.17 11.4 0.1 0.26 10.7 0.1 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 4 PPR_2 PF13041.6 KSA01782.1 - 2.9e-13 49.8 21.1 0.00017 21.7 0.6 7.2 8 1 1 9 9 9 5 PPR repeat family PPR_3 PF13812.6 KSA01782.1 - 5.5e-09 36.0 6.6 0.016 15.3 0.7 4.8 4 1 0 4 4 4 2 Pentatricopeptide repeat domain PPR PF01535.20 KSA01782.1 - 2.6e-07 30.4 14.8 0.69 10.3 0.1 9.1 10 0 0 10 10 10 2 PPR repeat PPR_1 PF12854.7 KSA01782.1 - 0.0049 16.5 0.2 1.4 8.7 0.0 4.0 3 0 0 3 3 3 1 PPR repeat RPM2 PF08579.11 KSA01782.1 - 0.0075 16.7 14.4 0.13 12.7 0.1 5.3 4 1 2 6 6 6 2 Mitochondrial ribonuclease P subunit (RPM2) mRNA_stabil PF13929.6 KSA01782.1 - 0.058 12.4 14.1 0.47 9.4 4.8 3.9 1 1 1 4 4 4 0 mRNA stabilisation PilP PF04351.13 KSA01782.1 - 0.066 13.2 0.4 0.23 11.4 0.0 2.1 2 0 0 2 2 2 0 Pilus assembly protein, PilP OmpH PF03938.14 KSA01782.1 - 3.7 7.9 6.4 1.9 8.8 0.1 3.1 3 1 0 3 3 3 0 Outer membrane protein (OmpH-like) Cyto_heme_lyase PF01265.17 KSA01783.1 - 7.6e-100 334.3 5.4 1.9e-99 332.9 5.4 1.6 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase SUV3_C PF12513.8 KSA01783.1 - 0.0094 15.9 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal OTU PF02338.19 KSA01784.1 - 1.1e-22 80.9 0.1 4.5e-22 78.9 0.0 2.0 2 1 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 KSA01784.1 - 0.0067 15.9 0.1 0.0067 15.9 0.1 2.5 2 1 0 2 2 2 1 Peptidase C65 Otubain Cyclin_N PF00134.23 KSA01785.1 - 5.2e-28 97.3 0.8 9.9e-28 96.4 0.8 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cupin_8 PF13621.6 KSA01786.1 - 2.6e-40 138.7 0.0 1.1e-39 136.7 0.0 1.8 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 KSA01786.1 - 7.5e-06 25.6 0.1 0.0028 17.2 0.0 2.9 3 0 0 3 3 3 2 Cupin superfamily protein S100PBPR PF15427.6 KSA01786.1 - 0.064 12.5 5.2 0.099 11.9 5.2 1.3 1 0 0 1 1 1 0 S100P-binding protein SDA1 PF05285.12 KSA01786.1 - 0.22 10.9 12.0 0.35 10.2 12.0 1.3 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 KSA01786.1 - 6 5.0 10.1 8.9 4.5 10.1 1.2 1 0 0 1 1 1 0 CDC45-like protein ETF_QO PF05187.13 KSA01788.1 - 2.4e-45 152.9 0.5 4.2e-45 152.2 0.5 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S DAO PF01266.24 KSA01788.1 - 3.1e-08 33.6 0.0 0.00017 21.3 0.0 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KSA01788.1 - 6.6e-07 28.7 0.6 0.0039 16.3 0.8 2.1 2 0 0 2 2 2 2 FAD binding domain HI0933_like PF03486.14 KSA01788.1 - 0.0001 21.1 0.6 0.0023 16.7 0.4 2.2 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 KSA01788.1 - 0.00021 21.5 0.2 0.00058 20.0 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KSA01788.1 - 0.00032 20.0 0.0 0.011 14.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KSA01788.1 - 0.00042 19.6 0.0 0.047 12.9 0.0 2.2 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 KSA01788.1 - 0.00083 18.7 0.2 0.0019 17.5 0.2 1.7 1 1 0 1 1 1 1 FAD binding domain Fer4_7 PF12838.7 KSA01788.1 - 0.004 17.7 0.8 0.01 16.4 0.8 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Trp_halogenase PF04820.14 KSA01788.1 - 0.006 15.5 0.1 0.48 9.2 0.1 2.2 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox PF00070.27 KSA01788.1 - 0.0091 16.5 1.2 0.64 10.6 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KSA01788.1 - 0.096 11.9 0.3 0.17 11.1 0.3 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Fer4_2 PF12797.7 KSA01788.1 - 0.11 12.6 0.5 0.31 11.2 0.5 1.7 1 0 0 1 1 1 0 4Fe-4S binding domain NAD_binding_9 PF13454.6 KSA01788.1 - 0.11 12.4 0.2 0.25 11.3 0.2 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding FAO_M PF16350.5 KSA01788.1 - 0.2 12.0 0.8 14 6.1 0.1 2.8 3 0 0 3 3 2 0 FAD dependent oxidoreductase central domain CDC24 PF06395.11 KSA01789.1 - 3.1e-35 120.3 0.5 8.1e-35 118.9 0.5 1.8 1 0 0 1 1 1 1 CDC24 Calponin PH_10 PF15411.6 KSA01789.1 - 6.5e-32 110.4 1.5 1.9e-31 108.9 1.5 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 KSA01789.1 - 1.4e-31 110.1 2.8 2e-31 109.6 1.0 2.2 2 0 0 2 2 2 1 RhoGEF domain PB1 PF00564.24 KSA01789.1 - 1.3e-05 25.1 0.8 4.6e-05 23.3 0.5 2.2 2 0 0 2 2 2 1 PB1 domain PH PF00169.29 KSA01789.1 - 0.035 14.6 0.5 0.11 13.0 0.5 1.9 1 0 0 1 1 1 0 PH domain WD40 PF00400.32 KSA01790.1 - 2.2e-13 50.4 8.2 8.9e-05 23.2 0.1 6.5 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KSA01790.1 - 2.2e-10 40.7 0.4 0.0058 16.9 0.1 4.7 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KSA01790.1 - 0.0011 18.9 3.1 0.2 11.5 0.5 4.0 2 2 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 KSA01790.1 - 0.0027 15.8 0.5 0.48 8.3 0.1 2.1 1 1 0 2 2 2 2 IKI3 family VID27 PF08553.10 KSA01790.1 - 0.019 14.0 0.1 0.029 13.4 0.1 1.3 1 0 0 1 1 1 0 VID27 C-terminal WD40-like domain MMS1_N PF10433.9 KSA01790.1 - 0.023 13.3 0.0 0.11 11.1 0.0 1.9 1 1 0 2 2 2 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term Cytochrom_D1 PF02239.16 KSA01790.1 - 0.024 13.2 0.2 0.075 11.5 0.0 1.8 2 0 0 2 2 2 0 Cytochrome D1 heme domain COPIIcoated_ERV PF07970.12 KSA01791.1 - 2.8e-74 249.7 0.3 3.4e-74 249.4 0.3 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 KSA01791.1 - 4e-28 97.6 2.6 9.7e-28 96.4 1.1 2.1 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) MRP-L46 PF11788.8 KSA01792.1 - 5.4e-43 146.5 1.1 7.8e-43 146.0 1.1 1.2 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 RRM_1 PF00076.22 KSA01793.1 - 1.3e-06 28.2 0.0 2.4e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.13 KSA01793.1 - 0.00094 20.0 0.6 0.0084 16.9 0.0 2.7 2 0 0 2 2 2 1 RNA polymerase II-binding domain. RRM_7 PF16367.5 KSA01793.1 - 0.0038 17.3 0.0 0.029 14.5 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif RTC4 PF14474.6 KSA01794.1 - 3.3e-32 111.2 0.1 6.4e-32 110.2 0.1 1.5 1 0 0 1 1 1 1 RTC4-like domain Pterin_bind PF00809.22 KSA01795.1 - 2.2e-63 214.2 0.0 1.8e-47 162.1 0.0 2.4 1 1 1 2 2 2 2 Pterin binding enzyme FolB PF02152.18 KSA01795.1 - 1.6e-37 128.5 0.5 3.9e-18 66.0 0.2 2.7 2 0 0 2 2 2 2 Dihydroneopterin aldolase HPPK PF01288.20 KSA01795.1 - 2.6e-32 111.6 0.0 7.1e-32 110.2 0.0 1.8 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) zf-CCHC PF00098.23 KSA01796.1 - 2e-48 160.4 62.7 1.6e-07 31.1 3.3 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.6 KSA01796.1 - 1.1e-15 57.1 39.9 0.012 15.3 0.3 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_3 PF13917.6 KSA01796.1 - 6.5e-05 22.8 53.5 0.18 11.8 2.7 7.0 1 1 6 7 7 7 6 Zinc knuckle zf-CCHC_5 PF14787.6 KSA01796.1 - 0.0001 21.9 40.0 0.032 13.9 0.4 7.1 6 1 1 7 7 7 5 GAG-polyprotein viral zinc-finger zf-CCHC_6 PF15288.6 KSA01796.1 - 0.02 14.7 47.7 0.039 13.8 2.4 7.0 5 1 2 7 7 7 0 Zinc knuckle Pro_isomerase PF00160.21 KSA01797.1 - 1.9e-24 86.8 0.0 2.9e-24 86.1 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 KSA01797.1 - 5.4e-16 58.2 0.1 4.2e-15 55.3 0.1 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ABC_tran PF00005.27 KSA01798.1 - 3.4e-35 121.5 0.0 4.4e-17 62.9 0.0 2.5 2 1 0 2 2 2 2 ABC transporter RLI PF04068.15 KSA01798.1 - 1.4e-12 47.2 5.7 4e-12 45.7 5.7 1.8 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI SMC_N PF02463.19 KSA01798.1 - 4.8e-10 39.2 2.0 0.016 14.6 0.0 4.1 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KSA01798.1 - 5.9e-09 36.2 5.8 0.2 11.4 1.0 4.3 2 2 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system Fer4 PF00037.27 KSA01798.1 - 4.5e-08 32.6 3.6 4.5e-08 32.6 3.6 2.7 2 0 0 2 2 2 1 4Fe-4S binding domain AAA PF00004.29 KSA01798.1 - 3.1e-06 27.6 0.1 0.023 15.1 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Fer4_6 PF12837.7 KSA01798.1 - 9.3e-06 25.5 3.1 9.3e-06 25.5 3.1 3.0 3 0 0 3 3 2 1 4Fe-4S binding domain Fer4_10 PF13237.6 KSA01798.1 - 2.3e-05 24.4 8.4 0.00062 19.8 0.1 2.4 2 0 0 2 2 2 1 4Fe-4S dicluster domain AAA_16 PF13191.6 KSA01798.1 - 2.5e-05 24.7 0.0 0.07 13.5 0.0 2.4 2 1 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.6 KSA01798.1 - 4.1e-05 23.5 0.6 0.22 11.2 0.0 3.1 2 1 0 3 3 3 2 AAA ATPase domain RsgA_GTPase PF03193.16 KSA01798.1 - 0.00015 21.7 0.1 0.69 9.8 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 KSA01798.1 - 0.0004 20.7 0.0 0.13 12.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain Fer4_21 PF14697.6 KSA01798.1 - 0.00043 20.4 12.6 0.0013 18.8 12.6 1.9 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 KSA01798.1 - 0.00054 19.9 9.7 0.00072 19.5 0.8 2.7 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_29 PF13555.6 KSA01798.1 - 0.0011 18.7 0.4 1.3 8.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain Fer4_9 PF13187.6 KSA01798.1 - 0.0012 19.0 10.9 0.0033 17.6 10.9 1.8 1 1 0 1 1 1 1 4Fe-4S dicluster domain Rad17 PF03215.15 KSA01798.1 - 0.0012 18.8 1.9 0.4 10.6 0.1 3.1 2 1 1 3 3 3 1 Rad17 P-loop domain RNA_helicase PF00910.22 KSA01798.1 - 0.0015 18.9 0.1 0.4 11.1 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_24 PF13479.6 KSA01798.1 - 0.002 17.9 0.9 0.32 10.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain Fer4_7 PF12838.7 KSA01798.1 - 0.0027 18.2 1.3 0.0027 18.2 1.3 2.6 1 1 2 3 3 3 1 4Fe-4S dicluster domain NB-ARC PF00931.22 KSA01798.1 - 0.0036 16.5 0.1 0.11 11.7 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain AAA_18 PF13238.6 KSA01798.1 - 0.006 17.1 0.0 5.5 7.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KSA01798.1 - 0.0061 17.1 0.0 1 9.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain Fer4_16 PF13484.6 KSA01798.1 - 0.0066 17.4 0.2 0.0066 17.4 0.2 2.8 2 1 0 2 2 1 1 4Fe-4S double cluster binding domain AAA_33 PF13671.6 KSA01798.1 - 0.009 16.2 0.0 2.8 8.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KSA01798.1 - 0.0092 15.9 1.8 1.2 9.0 0.0 2.9 3 0 0 3 3 3 1 NACHT domain SRP54 PF00448.22 KSA01798.1 - 0.011 15.4 3.6 0.32 10.6 0.1 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_30 PF13604.6 KSA01798.1 - 0.014 15.1 0.3 1.1 8.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 KSA01798.1 - 0.021 14.8 0.1 0.3 11.1 0.0 2.2 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_13 PF13166.6 KSA01798.1 - 0.044 12.4 0.9 0.07 11.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KSA01798.1 - 0.044 14.0 0.1 14 5.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KSA01798.1 - 0.051 13.6 1.1 0.43 10.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 KSA01798.1 - 0.065 13.3 0.1 14 5.8 0.0 2.9 3 0 0 3 3 2 0 AAA domain SbcCD_C PF13558.6 KSA01798.1 - 0.097 12.9 0.0 19 5.6 0.0 2.9 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit VirE PF05272.11 KSA01798.1 - 0.097 12.4 0.0 5.3 6.7 0.0 2.4 2 0 0 2 2 2 0 Virulence-associated protein E Fer4_8 PF13183.6 KSA01798.1 - 0.12 12.8 0.2 0.12 12.8 0.2 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain Thymidylate_kin PF02223.17 KSA01798.1 - 0.14 11.9 1.4 9.9 5.8 0.1 3.3 4 0 0 4 4 3 0 Thymidylate kinase AAA_7 PF12775.7 KSA01798.1 - 0.16 11.4 0.3 1.9 8.0 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Fer4_3 PF12798.7 KSA01798.1 - 1.5 9.9 15.8 0.16 13.0 3.5 2.9 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_17 PF13534.6 KSA01798.1 - 1.9 9.1 10.8 0.1 13.2 1.4 2.5 1 1 1 2 2 2 0 4Fe-4S dicluster domain SNF2_N PF00176.23 KSA01799.1 - 4e-60 203.4 0.1 6.6e-60 202.7 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Cdh1_DBD_1 PF18196.1 KSA01799.1 - 2.6e-34 118.1 1.7 2.6e-34 118.1 1.7 3.7 3 0 0 3 3 3 1 Chromodomain helicase DNA-binding domain 1 DUF4208 PF13907.6 KSA01799.1 - 1.7e-28 98.9 0.5 1.7e-28 98.9 0.5 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) Chromo PF00385.24 KSA01799.1 - 1.2e-25 89.2 11.2 3.7e-14 52.4 4.1 3.1 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 KSA01799.1 - 2.3e-20 73.0 0.0 7.3e-20 71.4 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KSA01799.1 - 5.8e-09 36.2 0.0 3.2e-08 33.7 0.0 2.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SLIDE PF09111.10 KSA01799.1 - 0.0017 18.4 0.2 0.018 15.0 0.0 2.8 2 0 0 2 2 2 1 SLIDE DEAD PF00270.29 KSA01799.1 - 0.0021 17.9 0.0 0.0043 16.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase CHDCT2 PF08074.11 KSA01799.1 - 0.0071 16.5 2.7 0.014 15.6 0.0 2.9 3 1 0 3 3 3 1 CHDCT2 (NUC038) domain RRM_1 PF00076.22 KSA01800.1 - 7.2e-81 266.0 14.8 2.2e-21 75.4 0.0 4.6 5 0 0 5 5 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 KSA01800.1 - 9.6e-23 80.2 2.3 3.8e-21 75.0 0.2 3.6 4 0 0 4 4 3 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 KSA01800.1 - 5.7e-08 32.4 0.0 0.43 10.2 0.0 3.8 1 1 2 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KSA01800.1 - 3.8e-07 29.9 0.0 4.1e-05 23.3 0.0 2.9 2 0 0 2 2 2 1 Occluded RNA-recognition motif RRM_3 PF08777.11 KSA01800.1 - 8.1e-05 22.6 10.3 0.3 11.2 3.4 4.6 3 1 1 4 4 4 2 RNA binding motif Limkain-b1 PF11608.8 KSA01800.1 - 0.00021 21.3 0.4 0.56 10.3 0.1 3.4 3 0 0 3 3 3 2 Limkain b1 Nup35_RRM_2 PF14605.6 KSA01800.1 - 0.00029 20.8 3.8 0.17 11.9 0.2 3.7 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 KSA01800.1 - 0.0016 18.5 0.9 26 5.0 0.0 4.7 4 1 0 4 4 4 0 RNA recognition motif YflT PF11181.8 KSA01800.1 - 0.0039 17.7 10.8 0.0056 17.2 0.6 3.5 4 0 0 4 4 4 1 Heat induced stress protein YflT SET_assoc PF11767.8 KSA01800.1 - 0.024 14.2 0.4 2.8 7.7 0.0 3.2 3 0 0 3 3 3 0 Histone lysine methyltransferase SET associated OB_RNB PF08206.11 KSA01800.1 - 0.058 13.1 0.6 10 5.9 0.0 3.4 3 0 0 3 3 3 0 Ribonuclease B OB domain Nefa_Nip30_N PF10187.9 KSA01800.1 - 0.065 13.6 0.4 0.065 13.6 0.4 3.9 5 0 0 5 5 4 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 GIY-YIG PF01541.24 KSA01800.1 - 0.13 12.6 2.7 1.4 9.2 0.5 2.6 2 0 0 2 2 2 0 GIY-YIG catalytic domain NOP5NT PF08156.13 KSA01800.1 - 0.93 9.9 10.7 15 6.1 0.0 5.3 6 0 0 6 6 6 0 NOP5NT (NUC127) domain DUF4078 PF13300.6 KSA01800.1 - 2.8 8.3 11.1 1 9.7 3.1 3.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4078) Glyco_transf_20 PF00982.21 KSA01801.1 - 2.1e-149 498.3 0.7 2.7e-149 497.9 0.7 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 KSA01801.1 - 1.1e-73 247.3 0.0 2.1e-73 246.3 0.0 1.5 2 0 0 2 2 2 1 Trehalose-phosphatase Abhydrolase_1 PF00561.20 KSA01802.1 - 6.8e-14 52.1 0.0 2.5e-13 50.3 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KSA01802.1 - 1.1e-07 31.3 0.0 4.3e-07 29.4 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KSA01802.1 - 0.0015 19.2 0.0 0.0023 18.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.11 KSA01802.1 - 0.023 14.0 0.0 0.071 12.4 0.0 1.7 1 1 1 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) DUF676 PF05057.14 KSA01802.1 - 0.04 13.4 0.0 0.072 12.6 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF726 PF05277.12 KSA01802.1 - 0.11 11.4 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF726) Arrestin_C PF02752.22 KSA01803.1 - 9.6e-19 68.2 0.1 9.6e-19 68.2 0.1 2.6 3 1 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KSA01803.1 - 5.7e-08 32.9 0.0 9.3e-05 22.5 0.0 2.9 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Sec62 PF03839.16 KSA01804.1 - 2.1e-72 243.1 1.7 2.8e-72 242.7 1.7 1.1 1 0 0 1 1 1 1 Translocation protein Sec62 DUF2207 PF09972.9 KSA01804.1 - 0.011 14.5 1.7 0.014 14.2 1.7 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4834 PF16118.5 KSA01804.1 - 0.057 14.4 1.1 0.16 12.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) CNH PF00780.22 KSA01805.1 - 0.00092 18.9 0.3 0.77 9.3 0.1 2.4 2 0 0 2 2 2 2 CNH domain WD40 PF00400.32 KSA01805.1 - 0.0035 18.1 0.0 3.3 8.8 0.0 2.9 2 0 0 2 2 2 2 WD domain, G-beta repeat ECH_2 PF16113.5 KSA01806.1 - 2.5e-107 359.2 0.0 3.6e-107 358.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 KSA01806.1 - 1.6e-24 86.6 0.1 8e-23 81.0 0.0 2.7 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase Actin PF00022.19 KSA01807.1 - 1.9e-68 230.9 0.0 1.6e-56 191.7 0.0 2.4 2 1 0 2 2 2 2 Actin Wtap PF17098.5 KSA01808.1 - 0.00043 20.2 14.7 0.00095 19.1 14.7 1.7 1 1 0 1 1 1 1 WTAP/Mum2p family DUF5603 PF18231.1 KSA01808.1 - 0.067 13.5 0.8 0.28 11.5 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5603) Peptidase_C97 PF05903.14 KSA01809.1 - 1.3e-39 135.4 0.0 1.5e-39 135.3 0.0 1.0 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.13 KSA01809.1 - 0.034 14.4 0.4 0.048 14.0 0.4 1.3 1 1 0 1 1 1 0 Lecithin retinol acyltransferase DUF1955 PF09205.10 KSA01809.1 - 0.092 12.5 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1955) EST1_DNA_bind PF10373.9 KSA01810.1 - 1.5e-50 172.3 10.5 1.5e-50 172.3 10.5 2.7 3 0 0 3 3 3 1 Est1 DNA/RNA binding domain EST1 PF10374.9 KSA01810.1 - 2.6e-19 70.2 0.4 2.6e-19 70.2 0.4 4.1 3 1 0 3 3 3 1 Telomerase activating protein Est1 FA_desaturase PF00487.24 KSA01811.1 - 1e-28 100.9 5.2 1.6e-28 100.3 5.2 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.10 KSA01811.1 - 6e-18 64.0 0.6 1.2e-17 63.1 0.6 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Adenyl_transf PF04439.12 KSA01811.1 - 0.17 10.9 0.3 0.58 9.2 0.1 1.8 2 0 0 2 2 2 0 Streptomycin adenylyltransferase tRNA-synt_His PF13393.6 KSA01812.1 - 1.2e-38 133.1 0.0 7.9e-32 110.8 0.0 2.1 2 0 0 2 2 2 2 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 KSA01812.1 - 2e-12 47.1 0.0 5.2e-12 45.8 0.0 1.8 1 0 0 1 1 1 1 Anticodon binding domain HGTP_anticodon2 PF12745.7 KSA01812.1 - 0.0066 16.0 0.4 0.018 14.5 0.0 1.9 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs tRNA-synt_2 PF00152.20 KSA01812.1 - 0.01 14.9 0.0 0.06 12.4 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class II (D, K and N) Ribosomal_60s PF00428.19 KSA01812.1 - 3.2 8.4 10.4 6.2 7.5 0.1 2.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein IDO PF01231.18 KSA01813.1 - 1.4e-152 508.5 0.0 1.6e-152 508.3 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase peroxidase PF00141.23 KSA01814.1 - 9.7e-43 146.5 0.0 1.5e-42 145.8 0.0 1.3 1 0 0 1 1 1 1 Peroxidase Granin PF01271.17 KSA01814.1 - 0.078 11.9 0.1 0.12 11.3 0.1 1.1 1 0 0 1 1 1 0 Granin (chromogranin or secretogranin) BAR PF03114.18 KSA01815.1 - 2.2e-58 197.8 4.4 2.8e-58 197.4 4.4 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 KSA01815.1 - 4.5e-15 55.0 0.9 1.1e-14 53.8 0.0 2.0 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KSA01815.1 - 3e-13 49.4 0.1 5.1e-13 48.7 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KSA01815.1 - 4.8e-08 32.6 0.0 1.1e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain RhoGAP PF00620.27 KSA01816.1 - 1e-36 126.1 1.3 2.6e-22 79.3 0.0 2.6 2 0 0 2 2 2 2 RhoGAP domain CLN3 PF02487.17 KSA01816.1 - 4.5 6.2 5.4 5.9 5.8 0.2 2.4 2 0 0 2 2 2 0 CLN3 protein Leo1 PF04004.13 KSA01817.1 - 1.5e-42 145.3 1.3 1.5e-42 145.3 1.3 3.4 3 1 0 3 3 3 1 Leo1-like protein ADK PF00406.22 KSA01818.1 - 1.1e-44 152.2 0.0 1.2e-44 152.0 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KSA01818.1 - 4.7e-21 75.7 0.0 7.7e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain ADK_lid PF05191.14 KSA01818.1 - 7.1e-13 48.3 0.0 1.3e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 KSA01818.1 - 0.00094 19.7 0.1 0.0025 18.3 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KSA01818.1 - 0.0072 16.5 0.1 0.025 14.7 0.0 1.8 2 1 0 2 2 2 1 AAA domain SWI2_SNF2 PF18766.1 KSA01818.1 - 0.16 11.7 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 SWI2/SNF2 ATPase DEAD_2 PF06733.15 KSA01819.1 - 4.2e-53 179.6 1.3 7.6e-53 178.7 1.3 1.5 1 0 0 1 1 1 1 DEAD_2 HBB PF06777.11 KSA01819.1 - 2.6e-48 164.2 2.3 4.7e-44 150.3 0.5 2.5 2 0 0 2 2 2 2 Helical and beta-bridge domain Helicase_C_2 PF13307.6 KSA01819.1 - 1.1e-43 149.3 0.0 2.7e-43 148.1 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain YtxC PF08812.11 KSA01819.1 - 0.0011 18.6 0.3 0.25 10.9 0.1 3.0 2 0 0 2 2 2 2 YtxC-like family ResIII PF04851.15 KSA01819.1 - 0.026 14.5 0.5 0.69 9.9 0.5 2.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Actin PF00022.19 KSA01820.1 - 8.4e-14 51.0 0.1 2e-11 43.1 0.1 2.6 1 1 0 1 1 1 1 Actin DUF2205 PF10224.9 KSA01822.1 - 3.6e-08 33.3 1.1 6e-08 32.6 1.1 1.3 1 0 0 1 1 1 1 Short coiled-coil protein DUF4200 PF13863.6 KSA01822.1 - 0.02 15.3 0.6 0.024 15.0 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) FlaF PF07309.11 KSA01822.1 - 0.056 13.5 0.2 0.071 13.1 0.2 1.2 1 0 0 1 1 1 0 Flagellar protein FlaF Hep_59 PF07052.11 KSA01822.1 - 0.29 11.9 3.5 0.31 11.8 1.6 1.9 1 1 1 2 2 2 0 Hepatocellular carcinoma-associated antigen 59 Fib_alpha PF08702.10 KSA01822.1 - 0.42 10.8 4.5 0.6 10.3 4.4 1.3 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family BAR PF03114.18 KSA01823.1 - 1.2e-55 188.8 1.3 1.4e-55 188.6 1.3 1.0 1 0 0 1 1 1 1 BAR domain DUF4164 PF13747.6 KSA01823.1 - 0.053 13.8 2.9 0.091 13.1 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4164) HAUS-augmin3 PF14932.6 KSA01823.1 - 0.082 12.5 0.4 0.33 10.5 0.1 1.9 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 Fib_alpha PF08702.10 KSA01823.1 - 0.23 11.6 1.2 9.6 6.4 0.1 2.7 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Jnk-SapK_ap_N PF09744.9 KSA01823.1 - 0.31 11.3 2.4 0.46 10.7 0.5 2.0 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 LPD34 PF18852.1 KSA01823.1 - 0.35 10.4 1.8 2 8.0 0.2 2.1 2 0 0 2 2 2 0 Large polyvalent protein associated domain 34 Sterol-sensing PF12349.8 KSA01824.1 - 0.00089 19.1 1.3 0.5 10.2 0.0 3.3 3 0 0 3 3 3 2 Sterol-sensing domain of SREBP cleavage-activation PsbX PF06596.11 KSA01824.1 - 0.061 13.3 1.4 0.3 11.1 1.4 2.2 1 0 0 1 1 1 0 Photosystem II reaction centre X protein (PsbX) E1-E2_ATPase PF00122.20 KSA01824.1 - 2.3 7.7 5.4 0.74 9.3 0.5 2.4 2 0 0 2 2 2 0 E1-E2 ATPase HIG_1_N PF04588.13 KSA01825.1 - 6.9e-06 26.2 0.4 6.9e-06 26.2 0.4 2.2 2 0 0 2 2 2 1 Hypoxia induced protein conserved region DUF929 PF06053.11 KSA01825.1 - 0.019 14.3 1.9 0.34 10.2 0.1 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF929) Pex24p PF06398.11 KSA01826.1 - 1.4e-91 307.2 20.1 1.6e-91 307.0 20.1 1.0 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Cgr1 PF03879.14 KSA01827.1 - 7.9e-32 109.9 30.6 9.4e-32 109.6 30.6 1.1 1 0 0 1 1 1 1 Cgr1 family SprA-related PF12118.8 KSA01827.1 - 4.3 6.4 10.2 4.8 6.2 10.2 1.1 1 0 0 1 1 1 0 SprA-related family FAM176 PF14851.6 KSA01827.1 - 6.9 6.3 11.9 8.7 6.0 11.9 1.1 1 0 0 1 1 1 0 FAM176 family TBP PF00352.21 KSA01828.1 - 3.5e-68 225.6 0.1 8.3e-33 112.2 0.1 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 KSA01828.1 - 2.5e-05 24.3 0.0 0.21 11.8 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 KSA01828.1 - 0.1 12.4 0.1 0.63 9.9 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) Exo_endo_phos PF03372.23 KSA01829.1 - 1.5e-06 27.9 0.0 6.7e-06 25.8 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 KSA01829.1 - 7.2e-06 25.8 0.7 0.074 12.9 0.0 3.1 3 0 0 3 3 3 2 Endonuclease-reverse transcriptase zf-GRF PF06839.12 KSA01829.1 - 3.4e-05 23.9 9.6 0.0004 20.4 9.6 2.5 1 1 0 1 1 1 1 GRF zinc finger Cohesin_load PF10345.9 KSA01831.1 - 8.7e-149 496.7 33.1 1.1e-148 496.4 33.1 1.1 1 0 0 1 1 1 1 Cohesin loading factor TPR_8 PF13181.6 KSA01831.1 - 0.016 15.4 8.8 0.17 12.1 0.1 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat DKCLD PF08068.12 KSA01832.1 - 4.4e-33 113.1 0.3 4.9e-32 109.8 0.4 2.3 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_C_2 PF16198.5 KSA01832.1 - 2.6e-22 78.7 0.4 5.1e-22 77.8 0.4 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.20 KSA01832.1 - 3.1e-20 71.9 0.8 7.2e-20 70.7 0.8 1.7 1 0 0 1 1 1 1 PUA domain TruB_N PF01509.18 KSA01832.1 - 6.1e-20 72.1 6.4 9.9e-19 68.2 0.0 3.7 2 1 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) UPF0113 PF03657.13 KSA01832.1 - 0.0022 18.2 0.0 0.0056 16.9 0.0 1.7 1 0 0 1 1 1 1 UPF0113 PUA domain GAGA_bind PF06217.12 KSA01832.1 - 1 9.6 17.4 1.4 9.2 17.4 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family AP3D1 PF06375.11 KSA01832.1 - 4.5 7.5 32.2 7.6 6.8 32.2 1.4 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 TFIIF_alpha PF05793.12 KSA01832.1 - 5.9 5.4 36.9 7.8 5.0 36.9 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF4746 PF15928.5 KSA01832.1 - 6.5 6.1 23.3 10 5.4 23.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) UEV PF05743.13 KSA01833.1 - 3.7e-28 97.8 0.4 7.5e-28 96.8 0.4 1.5 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.10 KSA01833.1 - 1.5e-14 53.7 0.0 6.8e-14 51.6 0.0 2.1 2 0 0 2 2 2 1 Vps23 core domain ATP_synt_H PF05493.13 KSA01834.1 - 1.7e-20 73.3 1.2 1.9e-20 73.1 1.2 1.0 1 0 0 1 1 1 1 ATP synthase subunit H ARL6IP6 PF15062.6 KSA01834.1 - 0.036 14.2 0.0 0.04 14.0 0.0 1.2 1 0 0 1 1 1 0 Haemopoietic lineage transmembrane helix VIT1 PF01988.19 KSA01834.1 - 0.074 12.9 0.7 0.076 12.9 0.7 1.0 1 0 0 1 1 1 0 VIT family DUF4131 PF13567.6 KSA01834.1 - 0.16 11.6 0.8 0.17 11.5 0.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) AA_permease PF00324.21 KSA01835.1 - 2.9e-127 425.2 44.8 3.3e-127 425.0 44.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KSA01835.1 - 5.5e-37 127.6 51.3 6.9e-37 127.3 51.3 1.1 1 0 0 1 1 1 1 Amino acid permease Nodulin_late PF07127.11 KSA01836.1 - 0.43 11.0 3.4 2 8.8 3.4 2.2 1 0 0 1 1 1 0 Late nodulin protein His_Phos_1 PF00300.22 KSA01837.1 - 7.3e-09 35.6 0.4 2.2e-08 34.0 0.4 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) HEAT PF02985.22 KSA01838.1 - 1e-40 134.2 11.5 0.0019 18.3 0.0 13.1 13 0 0 13 13 13 8 HEAT repeat HEAT_2 PF13646.6 KSA01838.1 - 2.8e-26 91.7 0.0 4.8e-07 30.1 0.0 8.0 4 3 3 7 7 7 5 HEAT repeats Vac14_Fab1_bd PF12755.7 KSA01838.1 - 1.4e-11 44.8 1.5 0.004 17.7 0.0 7.8 5 2 5 10 10 10 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KSA01838.1 - 2.2e-10 40.8 15.0 0.0022 18.1 0.3 6.0 2 2 3 5 5 5 4 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 KSA01838.1 - 6.1e-05 23.2 0.9 5.7 7.1 0.0 5.0 4 1 1 5 5 5 2 Required for nuclear transport of RNA pol II C-terminus 1 TAF6_C PF07571.13 KSA01838.1 - 0.00054 20.2 0.0 0.59 10.5 0.0 4.1 3 1 1 4 4 3 1 TAF6 C-terminal HEAT repeat domain API5 PF05918.11 KSA01838.1 - 0.00088 18.2 4.2 0.094 11.5 0.2 3.6 1 1 1 3 3 3 1 Apoptosis inhibitory protein 5 (API5) HEAT_EZ PF13513.6 KSA01838.1 - 0.001 19.5 5.0 6.6 7.3 0.0 7.0 9 1 0 9 9 7 1 HEAT-like repeat DNA_alkylation PF08713.11 KSA01838.1 - 0.0023 17.7 2.9 3.5 7.3 0.1 3.8 3 1 0 4 4 4 2 DNA alkylation repair enzyme PUL PF08324.11 KSA01838.1 - 0.018 14.3 1.2 0.36 10.0 0.0 2.5 2 0 0 2 2 2 0 PUL domain RIX1 PF08167.12 KSA01838.1 - 0.029 14.1 1.3 0.32 10.7 0.0 3.2 3 1 0 4 4 4 0 rRNA processing/ribosome biogenesis M11L PF11099.8 KSA01838.1 - 0.04 14.2 12.7 2.6 8.3 1.2 4.7 1 1 4 5 5 5 0 Apoptosis regulator M11L like Trp_Tyr_perm PF03222.13 KSA01838.1 - 0.086 11.9 0.0 0.18 10.8 0.0 1.5 1 0 0 1 1 1 0 Tryptophan/tyrosine permease family RhoGAP PF00620.27 KSA01838.1 - 0.17 11.7 3.1 8.2 6.2 0.1 3.7 4 0 0 4 4 4 0 RhoGAP domain V-ATPase_H_C PF11698.8 KSA01838.1 - 0.24 11.5 3.4 1.5 8.9 0.9 3.2 2 2 1 3 3 3 0 V-ATPase subunit H DASH_Ask1 PF08655.10 KSA01838.1 - 0.27 11.2 4.6 2.9 7.9 0.2 4.0 4 1 0 4 4 4 0 DASH complex subunit Ask1 Cohesin_HEAT PF12765.7 KSA01838.1 - 2.4 8.5 4.4 12 6.3 0.0 4.2 6 0 0 6 6 5 0 HEAT repeat associated with sister chromatid cohesion Fe-S_biosyn PF01521.20 KSA01839.1 - 8.8e-11 42.0 0.3 2.4e-10 40.6 0.3 1.7 1 1 0 1 1 1 1 Iron-sulphur cluster biosynthesis PMT PF02366.18 KSA01840.1 - 2.6e-90 302.3 19.0 2.6e-90 302.3 19.0 2.2 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KSA01840.1 - 6.7e-60 202.1 12.2 6.7e-60 202.1 12.2 2.4 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KSA01840.1 - 5.6e-22 78.5 0.1 1e-21 77.7 0.1 1.3 1 0 0 1 1 1 1 MIR domain CENP-L PF13092.6 KSA01841.1 - 0.0015 18.8 0.0 0.056 13.7 0.0 2.3 1 1 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 Gp_dh_C PF02800.20 KSA01842.1 - 2.8e-70 235.0 0.0 4.9e-70 234.2 0.0 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 KSA01842.1 - 1.6e-40 137.5 0.0 3.2e-40 136.5 0.0 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KSA01842.1 - 0.005 16.2 0.1 0.011 15.1 0.0 1.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DapB_N PF01113.20 KSA01842.1 - 0.026 14.6 0.5 0.082 13.0 0.0 2.1 3 0 0 3 3 3 0 Dihydrodipicolinate reductase, N-terminus Aldo_ket_red PF00248.21 KSA01843.1 - 4.9e-36 124.4 0.0 4.5e-34 118.0 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Zn_clus PF00172.18 KSA01844.1 - 2.8e-08 33.8 15.5 4.5e-08 33.1 15.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain OB_NTP_bind PF07717.16 KSA01845.1 - 4.1e-14 52.7 0.0 1.2e-13 51.2 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KSA01845.1 - 1.5e-13 51.0 2.1 5.7e-13 49.2 0.0 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain HA2 PF04408.23 KSA01845.1 - 3.6e-12 46.5 0.0 9.6e-12 45.2 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) RWD PF05773.22 KSA01845.1 - 1.7e-10 41.2 1.4 5.7e-10 39.5 0.8 2.4 2 0 0 2 2 2 1 RWD domain DEAD PF00270.29 KSA01845.1 - 7.9e-10 38.8 0.5 1.8e-09 37.6 0.5 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KSA01845.1 - 1.4e-08 34.9 0.5 5.7e-08 33.0 0.5 2.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KSA01845.1 - 0.0016 18.8 0.0 0.0034 17.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KSA01845.1 - 0.0021 17.8 0.0 0.0051 16.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 KSA01845.1 - 0.0051 17.1 0.7 0.025 14.9 0.3 2.4 1 1 1 2 2 2 1 AAA domain T2SSE PF00437.20 KSA01845.1 - 0.0059 15.7 0.0 0.011 14.8 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_14 PF13173.6 KSA01845.1 - 0.0072 16.4 1.1 0.48 10.5 1.1 3.1 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 KSA01845.1 - 0.025 15.1 0.3 1 9.9 0.0 3.2 2 0 0 2 2 2 0 ABC transporter PhoH PF02562.16 KSA01845.1 - 0.028 13.9 0.0 0.1 12.0 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein OPT PF03169.15 KSA01846.1 - 9.7e-134 447.3 46.7 1.1e-133 447.1 46.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF3270 PF11674.8 KSA01846.1 - 0.84 9.9 4.2 0.34 11.1 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3270) UPF0016 PF01169.19 KSA01846.1 - 1.9 8.9 0.0 1.9 8.9 0.0 3.9 4 1 0 4 4 4 0 Uncharacterized protein family UPF0016 TFIID_20kDa PF03847.13 KSA01847.1 - 6.1e-30 103.5 0.2 1.3e-29 102.5 0.2 1.6 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A TFIID-31kDa PF02291.15 KSA01847.1 - 0.0014 18.7 0.6 0.015 15.4 0.0 2.4 2 0 0 2 2 2 1 Transcription initiation factor IID, 31kD subunit BLOC1_2 PF10046.9 KSA01847.1 - 0.01 16.1 4.2 0.01 16.1 4.2 2.0 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CBFD_NFYB_HMF PF00808.23 KSA01847.1 - 0.054 13.8 0.0 0.14 12.5 0.0 1.7 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Adaptin_binding PF10199.9 KSA01847.1 - 0.091 13.4 2.8 0.32 11.6 2.5 2.1 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 DHR10 PF18595.1 KSA01847.1 - 0.65 10.1 9.7 0.31 11.1 0.7 2.3 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain Cullin PF00888.22 KSA01848.1 - 7e-16 58.0 4.6 7e-16 58.0 4.6 2.0 2 1 0 2 2 2 1 Cullin family Cullin_binding PF03556.15 KSA01849.1 - 1.6e-31 109.2 2.8 2.8e-31 108.5 2.8 1.4 1 0 0 1 1 1 1 Cullin binding HLH PF00010.26 KSA01850.1 - 1.2e-11 44.4 0.0 4.4e-11 42.6 0.0 2.1 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain La PF05383.17 KSA01851.1 - 3.2e-11 43.1 0.2 5.5e-11 42.3 0.2 1.4 1 0 0 1 1 1 1 La domain Slu7 PF11708.8 KSA01852.1 - 1.2e-44 153.1 27.8 2.1e-43 149.0 27.8 2.2 1 1 0 1 1 1 1 Pre-mRNA splicing Prp18-interacting factor SRP1_TIP1 PF00660.17 KSA01852.1 - 0.036 14.1 0.1 9.3 6.4 0.0 2.5 2 0 0 2 2 2 0 Seripauperin and TIP1 family Nop52 PF05997.12 KSA01853.1 - 4.4e-79 265.3 6.8 5.3e-79 265.0 6.8 1.1 1 0 0 1 1 1 1 Nucleolar protein,Nop52 SecE PF00584.20 KSA01854.1 - 1.4e-15 56.9 0.1 1.6e-15 56.8 0.1 1.0 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex DUF4473 PF14747.6 KSA01854.1 - 0.096 13.2 0.0 0.12 13.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4473) ATP13 PF12921.7 KSA01855.1 - 3.9e-33 113.7 3.6 4.4e-33 113.6 0.3 2.8 3 0 0 3 3 3 1 Mitochondrial ATPase expression Dot_icm_IcmQ PF09475.10 KSA01855.1 - 0.015 14.8 0.2 0.044 13.3 0.2 1.8 1 0 0 1 1 1 0 Dot/Icm secretion system protein (dot_icm_IcmQ) DUSP PF06337.12 KSA01855.1 - 0.99 10.1 4.5 2.5 8.8 0.2 3.1 3 0 0 3 3 3 0 DUSP domain ECH_1 PF00378.20 KSA01856.1 - 4.9e-28 98.1 0.0 8e-28 97.4 0.0 1.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KSA01856.1 - 2.7e-26 92.9 0.0 3.1e-26 92.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase DEAD PF00270.29 KSA01857.1 - 1.8e-49 167.9 0.0 5.3e-49 166.4 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KSA01857.1 - 8.7e-25 87.2 0.1 5.2e-24 84.7 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AA_permease PF00324.21 KSA01858.1 - 9.7e-53 179.4 39.3 1.2e-52 179.1 39.3 1.1 1 0 0 1 1 1 1 Amino acid permease SLC12 PF03522.15 KSA01858.1 - 3.5e-08 32.9 22.5 6e-06 25.6 0.0 4.5 3 1 2 5 5 5 3 Solute carrier family 12 PEP-utilisers_N PF05524.13 KSA01861.1 - 0.081 13.1 2.2 1.3 9.2 0.5 2.4 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal UPF0184 PF03670.13 KSA01861.1 - 0.72 10.3 8.5 2.8 8.4 1.2 3.0 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0184) DUF848 PF05852.11 KSA01861.1 - 4 7.5 12.3 1.6 8.8 6.9 2.4 2 1 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) CENP-H PF05837.12 KSA01861.1 - 5 7.6 17.2 0.29 11.6 4.0 3.4 2 1 1 3 3 3 0 Centromere protein H (CENP-H) TAF6_C PF07571.13 KSA01862.1 - 1.6e-29 102.0 0.3 5e-29 100.5 0.2 1.9 2 0 0 2 2 2 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 KSA01862.1 - 3.5e-26 91.2 0.2 1.6e-25 89.0 0.0 2.2 2 0 0 2 2 2 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 KSA01862.1 - 5.1e-05 23.6 1.0 0.00084 19.7 0.2 2.2 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KSA01862.1 - 0.0045 17.2 0.1 0.022 15.0 0.1 2.2 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Lac_bphage_repr PF06543.12 KSA01862.1 - 0.8 9.7 7.0 0.24 11.4 3.0 2.2 2 0 0 2 2 2 0 Lactococcus bacteriophage repressor SLD3 PF08639.10 KSA01863.1 - 3.1e-63 214.4 19.0 3.1e-63 214.4 19.0 1.5 2 0 0 2 2 2 1 DNA replication regulator SLD3 UPF0542 PF15086.6 KSA01863.1 - 4.3 7.3 7.5 1.4 8.9 2.0 2.8 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 Pkinase PF00069.25 KSA01864.1 - 2.4e-56 191.0 0.0 4e-56 190.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KSA01864.1 - 1.1e-20 74.0 0.0 1.7e-20 73.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KSA01864.1 - 4.8e-05 22.8 0.0 0.00011 21.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KSA01864.1 - 0.00071 19.6 0.0 0.0011 18.9 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family PAS_9 PF13426.7 KSA01864.1 - 0.00081 19.6 0.6 0.08 13.2 0.1 3.5 3 1 0 3 3 3 1 PAS domain Kdo PF06293.14 KSA01864.1 - 0.00088 18.7 0.0 0.0026 17.2 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KSA01864.1 - 0.0055 15.7 0.1 0.016 14.2 0.1 1.7 1 0 0 1 1 1 1 Haspin like kinase domain PAS PF00989.25 KSA01864.1 - 0.0063 16.5 0.0 2.5 8.1 0.0 3.2 2 1 0 2 2 2 1 PAS fold Pkinase_fungal PF17667.1 KSA01864.1 - 0.04 12.7 0.0 0.072 11.8 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Kinase-PolyVal PF18762.1 KSA01864.1 - 0.12 12.3 0.7 1.1 9.2 0.1 2.5 2 0 0 2 2 2 0 Serine/Threonine/Tyrosine Kinase found in polyvalent proteins FTA2 PF13095.6 KSA01864.1 - 0.13 11.8 0.3 0.51 9.9 0.1 2.0 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 KSA01864.1 - 0.22 11.1 3.0 0.2 11.3 0.1 2.3 3 0 0 3 3 3 0 RIO1 family LDB19 PF13002.7 KSA01865.1 - 1.3e-59 201.1 0.9 3.1e-59 199.9 0.9 1.7 1 0 0 1 1 1 1 Arrestin_N terminal like Arrestin_N PF00339.29 KSA01865.1 - 0.00014 21.9 0.3 0.00047 20.2 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Cadherin_4 PF17803.1 KSA01865.1 - 0.55 10.9 3.7 0.21 12.3 0.5 2.1 2 0 0 2 2 2 0 Bacterial cadherin-like domain Actin PF00022.19 KSA01866.1 - 2.9e-67 227.1 0.0 4.4e-66 223.2 0.0 1.9 1 1 0 1 1 1 1 Actin PIG-L PF02585.17 KSA01867.1 - 1.8e-23 83.6 0.0 2.4e-23 83.2 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Sigma_reg_N PF13800.6 KSA01867.1 - 0.1 12.9 3.9 5 7.5 0.3 2.5 2 0 0 2 2 2 0 Sigma factor regulator N-terminal Methyltransf_11 PF08241.12 KSA01868.1 - 2.6e-17 63.3 0.0 5.1e-17 62.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KSA01868.1 - 2.7e-16 60.0 0.0 4.4e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KSA01868.1 - 4.8e-14 52.4 0.0 6.8e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KSA01868.1 - 9.6e-14 51.9 0.0 1.7e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KSA01868.1 - 2.1e-11 43.9 0.0 2.9e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KSA01868.1 - 2.1e-07 30.5 0.0 3.7e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KSA01868.1 - 0.00025 20.6 0.0 0.00086 18.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain Spermine_synth PF01564.17 KSA01868.1 - 0.00059 19.3 0.0 0.0015 18.0 0.0 1.7 2 0 0 2 2 2 1 Spermine/spermidine synthase domain Methyltransf_16 PF10294.9 KSA01868.1 - 0.0021 17.8 0.0 0.0034 17.1 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_3 PF01596.17 KSA01868.1 - 0.0064 15.7 0.0 0.0092 15.2 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase PrmA PF06325.13 KSA01868.1 - 0.0076 15.7 0.0 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) NodS PF05401.11 KSA01868.1 - 0.016 14.8 0.0 0.04 13.5 0.0 1.6 1 1 0 1 1 1 0 Nodulation protein S (NodS) CheR PF01739.18 KSA01868.1 - 0.082 12.4 0.0 0.25 10.8 0.0 1.9 1 1 0 1 1 1 0 CheR methyltransferase, SAM binding domain RGS PF00615.19 KSA01868.1 - 0.089 13.1 0.0 0.41 10.9 0.0 2.0 2 0 0 2 2 2 0 Regulator of G protein signaling domain PCMT PF01135.19 KSA01868.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Fungal_trans PF04082.18 KSA01869.1 - 6.1e-38 130.4 2.3 1.2e-37 129.4 2.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KSA01869.1 - 7.1e-10 38.8 10.2 1.3e-09 38.1 10.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HhH-GPD PF00730.25 KSA01870.1 - 3.3e-17 62.9 0.0 5.2e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KSA01870.1 - 3.8e-05 23.3 0.0 0.00011 21.9 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif DNA_primase_S PF01896.19 KSA01870.1 - 0.0031 17.6 0.0 0.0058 16.7 0.0 1.3 1 0 0 1 1 1 1 DNA primase small subunit Exo_endo_phos PF03372.23 KSA01871.1 - 2.9e-15 56.4 0.0 4.2e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_8 PF13855.6 KSA01872.1 - 1.2e-21 76.2 23.1 6.5e-11 41.8 3.2 2.8 1 1 2 3 3 3 3 Leucine rich repeat Exo_endo_phos PF03372.23 KSA01872.1 - 8.9e-21 74.5 0.0 4.7e-20 72.1 0.0 2.2 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.7 KSA01872.1 - 1.6e-12 47.4 12.1 2.1e-08 34.3 1.9 3.0 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KSA01872.1 - 0.0027 18.0 14.6 2.8 8.8 0.0 5.5 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_6 PF13516.6 KSA01872.1 - 0.015 15.3 5.6 0.2 11.8 0.2 3.7 3 0 0 3 3 3 0 Leucine Rich repeat Retrotrans_gag PF03732.17 KSA01873.1 - 0.01 16.1 0.0 0.021 15.1 0.0 1.5 1 0 0 1 1 1 0 Retrotransposon gag protein zf-CCHC PF00098.23 KSA01873.1 - 0.022 14.8 1.1 0.022 14.8 1.1 1.6 2 0 0 2 2 2 0 Zinc knuckle tRNA_anti-codon PF01336.25 KSA01874.1 - 2.5e-09 37.0 0.3 5.3e-09 35.9 0.1 1.7 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain RPA_C PF08784.11 KSA01874.1 - 6e-08 33.3 0.7 2.5e-07 31.3 0.1 2.2 2 0 0 2 2 2 1 Replication protein A C terminal RMI2 PF16100.5 KSA01874.1 - 0.047 13.5 0.0 0.085 12.7 0.0 1.5 1 0 0 1 1 1 0 RecQ-mediated genome instability protein 2 SNF2_N PF00176.23 KSA01875.1 - 7.3e-45 153.2 0.0 3.1e-44 151.1 0.0 2.0 1 1 0 1 1 1 1 SNF2 family N-terminal domain zf-C3HC4_3 PF13920.6 KSA01875.1 - 8.2e-09 35.2 8.8 1.9e-08 34.1 8.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KSA01875.1 - 2.5e-08 33.7 10.5 5.8e-08 32.5 10.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KSA01875.1 - 3.3e-08 33.7 9.5 7.1e-08 32.7 9.5 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KSA01875.1 - 1.9e-07 30.8 9.9 4.5e-07 29.6 9.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KSA01875.1 - 2.2e-06 27.9 6.2 6.3e-06 26.4 6.2 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain Helicase_C PF00271.31 KSA01875.1 - 8.1e-06 26.2 0.0 3.1e-05 24.3 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Prok-RING_4 PF14447.6 KSA01875.1 - 2.2e-05 24.2 7.3 4.4e-05 23.2 7.3 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KSA01875.1 - 0.00027 20.8 8.0 0.00066 19.6 8.0 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KSA01875.1 - 0.00062 19.7 6.9 0.0012 18.8 6.2 1.9 2 0 0 2 2 2 1 RING-type zinc-finger DNA_pol_B_exo2 PF10108.9 KSA01875.1 - 0.011 15.4 1.7 0.053 13.2 0.1 2.7 2 0 0 2 2 2 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB zf-P11 PF03854.14 KSA01875.1 - 0.027 14.1 7.6 0.07 12.8 7.6 1.7 1 0 0 1 1 1 0 P-11 zinc finger zf-RING_4 PF14570.6 KSA01875.1 - 0.098 12.5 5.0 0.28 11.0 5.0 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 KSA01875.1 - 0.22 11.6 3.2 0.47 10.5 3.2 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 KSA01875.1 - 0.42 10.8 6.9 1.2 9.4 6.9 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Pkinase PF00069.25 KSA01876.1 - 3.3e-71 239.8 0.0 7.3e-71 238.6 0.0 1.6 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KSA01876.1 - 1.8e-33 115.9 0.1 5.4e-33 114.4 0.1 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KSA01876.1 - 0.0002 20.8 0.6 0.083 12.2 0.1 2.4 2 1 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 KSA01876.1 - 0.0035 16.2 0.1 0.0073 15.1 0.1 1.6 1 1 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 KSA01876.1 - 0.054 13.1 0.7 1.3 8.6 0.3 2.4 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 HAD PF12710.7 KSA01877.1 - 7.7e-26 91.6 0.0 9.6e-26 91.3 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 KSA01877.1 - 1.3e-06 28.1 0.1 3.1e-06 26.9 0.0 1.7 2 1 0 2 2 2 1 Pyrimidine 5'-nucleotidase (UMPH-1) Put_Phosphatase PF06888.12 KSA01877.1 - 0.00011 21.6 0.0 0.00016 21.2 0.0 1.3 1 0 0 1 1 1 1 Putative Phosphatase HAD_2 PF13419.6 KSA01877.1 - 0.034 14.2 0.0 4.6 7.3 0.0 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KSA01877.1 - 0.038 14.3 0.2 0.8 10.0 0.1 2.9 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Nramp PF01566.18 KSA01878.1 - 5.5e-84 282.2 20.9 5.7e-50 170.3 7.0 2.3 3 0 0 3 3 3 2 Natural resistance-associated macrophage protein DUF1576 PF07613.11 KSA01878.1 - 0.0016 18.0 3.0 0.0016 18.0 3.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1576) Pkinase PF00069.25 KSA01879.1 - 1.3e-72 244.3 0.0 1.8e-72 243.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KSA01879.1 - 6.3e-39 133.8 0.0 9e-39 133.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KSA01879.1 - 1e-05 25.0 0.0 2.5e-05 23.7 0.0 1.6 1 1 0 1 1 1 1 Kinase-like FTA2 PF13095.6 KSA01879.1 - 0.015 14.9 0.1 0.58 9.7 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KSA01879.1 - 0.02 14.2 0.0 0.12 11.7 0.0 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KSA01879.1 - 0.041 12.8 2.6 0.09 11.7 2.6 1.5 1 1 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 KSA01879.1 - 0.11 12.1 0.2 0.4 10.2 0.2 1.9 1 1 0 1 1 1 0 RIO1 family TFIIS_C PF01096.18 KSA01880.1 - 1e-15 57.3 13.7 1.3e-15 56.9 4.4 3.0 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 KSA01880.1 - 1.9e-12 46.8 5.1 1.9e-12 46.8 5.1 2.8 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit DZR PF12773.7 KSA01880.1 - 0.00029 20.8 7.6 0.026 14.5 0.6 2.3 2 0 0 2 2 2 2 Double zinc ribbon Zn_ribbon_recom PF13408.6 KSA01880.1 - 0.055 14.0 5.3 0.75 10.4 0.3 2.2 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain UPF0547 PF10571.9 KSA01880.1 - 0.32 11.1 0.0 0.32 11.1 0.0 3.1 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 zf-GRF PF06839.12 KSA01880.1 - 0.51 10.5 9.0 0.52 10.5 0.2 3.1 3 0 0 3 3 3 0 GRF zinc finger DUF3268 PF11672.8 KSA01880.1 - 0.54 10.6 6.5 3.3 8.1 1.0 2.2 2 0 0 2 2 2 0 zinc-finger-containing domain zinc_ribbon_9 PF14369.6 KSA01880.1 - 0.64 10.3 8.1 5.6 7.3 1.0 3.0 3 0 0 3 3 3 0 zinc-ribbon C1_4 PF07975.12 KSA01880.1 - 1 9.7 13.6 15 5.9 1.8 3.4 2 2 1 3 3 3 0 TFIIH C1-like domain OrfB_Zn_ribbon PF07282.11 KSA01880.1 - 1.5 8.8 10.1 3.2 7.8 3.4 2.4 2 1 0 2 2 2 0 Putative transposase DNA-binding domain Zn_Tnp_IS1595 PF12760.7 KSA01880.1 - 2.3 8.3 11.2 2.4 8.2 2.9 2.7 2 2 0 2 2 2 0 Transposase zinc-ribbon domain Lar_restr_allev PF14354.6 KSA01880.1 - 5 7.6 11.1 0.35 11.3 1.9 2.6 2 1 0 2 2 2 0 Restriction alleviation protein Lar Zn-ribbon_8 PF09723.10 KSA01880.1 - 6.6 6.9 15.2 3.6 7.8 0.2 3.8 3 1 1 4 4 4 0 Zinc ribbon domain Nudix_N_2 PF14803.6 KSA01880.1 - 7 6.7 11.0 1.8 8.6 0.6 3.2 3 0 0 3 3 3 0 Nudix N-terminal Ribosomal_L12 PF00542.19 KSA01881.1 - 5.6e-22 77.9 7.5 5.6e-22 77.9 7.5 2.4 3 0 0 3 3 3 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 KSA01881.1 - 1.1e-15 57.1 2.0 1.5e-15 56.6 0.2 2.2 2 0 0 2 2 2 1 Ribosomal protein L7/L12 dimerisation domain AFT PF08731.11 KSA01883.1 - 7.7e-29 100.3 5.6 8.9e-17 61.5 0.3 3.8 3 1 1 4 4 4 2 Transcription factor AFT UPF0058 PF01893.16 KSA01883.1 - 0.087 13.1 1.0 0.31 11.4 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0058 DUF3038 PF11237.8 KSA01883.1 - 8.3 6.4 8.8 0.52 10.3 3.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3038) PAC2 PF09754.9 KSA01884.1 - 3e-22 79.7 0.0 3.5e-22 79.5 0.0 1.1 1 0 0 1 1 1 1 PAC2 family Fungal_trans PF04082.18 KSA01885.1 - 7.4e-16 58.0 2.3 2e-15 56.6 2.3 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KSA01885.1 - 2.4e-10 40.4 12.9 4.1e-10 39.6 12.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HTH_Bact PF18768.1 KSA01885.1 - 0.086 12.4 0.7 0.21 11.2 0.7 1.6 1 0 0 1 1 1 0 Helix-turn-helix bacterial domain CoA_trans PF01144.23 KSA01886.1 - 3.9e-96 320.6 0.1 5.3e-57 192.7 0.0 2.0 2 0 0 2 2 2 2 Coenzyme A transferase Mal_decarbox_Al PF16957.5 KSA01886.1 - 0.0046 15.4 0.1 0.11 10.8 0.0 2.1 2 0 0 2 2 2 2 Malonate decarboxylase, alpha subunit, transporter UPF0052 PF01933.18 KSA01886.1 - 0.045 13.0 0.0 0.071 12.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0052 Dioxygenase_C PF00775.21 KSA01887.1 - 5.7e-41 139.9 0.0 8.7e-41 139.3 0.0 1.3 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 KSA01887.1 - 2.5e-31 107.3 0.0 5.5e-31 106.3 0.0 1.6 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 KSA01887.1 - 0.00075 19.7 0.0 0.0075 16.5 0.0 2.3 1 1 0 1 1 1 1 Carboxypeptidase regulatory-like domain TTR-52 PF01060.23 KSA01887.1 - 0.053 14.2 0.0 0.35 11.6 0.0 2.3 2 1 0 2 2 2 0 Transthyretin-like family Exotox-A_bind PF09101.10 KSA01887.1 - 0.074 12.4 0.0 0.25 10.7 0.0 1.7 2 0 0 2 2 2 0 Exotoxin A binding DHquinase_II PF01220.19 KSA01888.1 - 3.3e-61 205.0 0.4 3.7e-61 204.8 0.4 1.0 1 0 0 1 1 1 1 Dehydroquinase class II YwiC PF14256.6 KSA01888.1 - 0.012 15.9 0.0 0.015 15.6 0.0 1.2 1 0 0 1 1 1 0 YwiC-like protein PLDc_2 PF13091.6 KSA01888.1 - 0.09 12.7 0.1 0.12 12.2 0.1 1.2 1 0 0 1 1 1 0 PLD-like domain Flavin_Reduct PF01613.18 KSA01889.1 - 1.1e-20 74.2 0.0 1.6e-20 73.7 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain TFIIS_C PF01096.18 KSA01890.1 - 1.2e-16 60.2 1.3 1.2e-16 60.2 1.3 2.5 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 KSA01890.1 - 3.9e-06 26.6 10.7 4.6e-05 23.2 1.2 3.1 2 1 0 2 2 2 1 RNA polymerases M/15 Kd subunit DZR PF12773.7 KSA01890.1 - 0.00057 19.9 5.2 0.32 11.1 1.1 2.6 2 1 0 2 2 2 2 Double zinc ribbon TF_Zn_Ribbon PF08271.12 KSA01890.1 - 0.016 14.7 12.3 0.044 13.3 3.0 2.8 2 2 0 2 2 2 0 TFIIB zinc-binding zf-TFIIB PF13453.6 KSA01890.1 - 0.026 13.8 0.6 0.026 13.8 0.6 2.0 2 0 0 2 2 2 0 Transcription factor zinc-finger zf-C4_Topoisom PF01396.19 KSA01890.1 - 0.029 14.1 4.8 0.08 12.7 2.6 2.7 2 1 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_4 PF13717.6 KSA01890.1 - 0.032 14.2 4.5 4.2 7.4 0.1 3.8 4 0 0 4 4 4 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 KSA01890.1 - 0.039 14.1 8.8 2.3 8.4 0.0 3.4 3 0 0 3 3 3 0 Zinc ribbon domain zinc_ribbon_2 PF13240.6 KSA01890.1 - 0.049 13.4 14.2 0.19 11.5 0.2 3.6 4 0 0 4 4 3 0 zinc-ribbon domain Nudix_N_2 PF14803.6 KSA01890.1 - 0.059 13.3 4.9 9.1 6.3 1.9 3.2 2 1 0 2 2 2 0 Nudix N-terminal Zn_Tnp_IS1595 PF12760.7 KSA01890.1 - 0.077 13.0 4.1 0.15 12.0 0.6 2.3 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-ribbon_3 PF13248.6 KSA01890.1 - 0.13 11.7 8.9 1.4 8.5 0.4 3.5 3 0 0 3 3 3 0 zinc-ribbon domain Mu-like_Com PF10122.9 KSA01890.1 - 0.19 11.2 1.5 0.46 10.0 0.0 2.2 2 0 0 2 2 2 0 Mu-like prophage protein Com DUF35_N PF12172.8 KSA01890.1 - 0.23 11.4 4.3 9.5 6.2 0.0 3.1 3 0 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) DUF2072 PF09845.9 KSA01890.1 - 0.24 11.6 0.1 0.24 11.6 0.1 2.5 1 1 1 3 3 3 0 Zn-ribbon containing protein Ogr_Delta PF04606.12 KSA01890.1 - 0.37 10.8 5.1 1.9 8.5 5.1 2.2 1 1 0 1 1 1 0 Ogr/Delta-like zinc finger Stc1 PF12898.7 KSA01890.1 - 0.41 11.2 6.0 0.53 10.9 0.3 2.3 1 1 1 2 2 2 0 Stc1 domain Fer4_10 PF13237.6 KSA01890.1 - 0.49 10.6 6.1 3 8.0 2.4 3.0 2 1 0 2 2 2 0 4Fe-4S dicluster domain zf-IS66 PF13005.7 KSA01890.1 - 0.61 10.5 7.9 6 7.4 0.2 3.2 3 0 0 3 3 3 0 zinc-finger binding domain of transposase IS66 zf-C2H2_4 PF13894.6 KSA01890.1 - 1.5 9.9 12.5 21 6.3 0.6 4.2 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KSA01890.1 - 2.3 8.8 19.3 0.56 10.8 1.5 4.2 4 0 0 4 4 4 0 Zinc finger, C2H2 type Zn_Tnp_IS91 PF14319.6 KSA01890.1 - 3.2 7.8 6.6 2.4 8.3 1.2 2.5 1 1 0 2 2 2 0 Transposase zinc-binding domain zinc_ribbon_15 PF17032.5 KSA01890.1 - 4.1 8.2 9.9 13 6.6 6.6 2.8 1 1 2 3 3 3 0 zinc-ribbon family zf-H2C2_2 PF13465.6 KSA01890.1 - 6.3 7.4 12.8 7 7.3 0.2 3.5 4 0 0 4 4 3 0 Zinc-finger double domain zinc_ribbon_13 PF09855.9 KSA01890.1 - 8.8 6.6 9.4 1.2e+02 2.9 5.3 3.2 2 1 0 2 2 2 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) OrfB_Zn_ribbon PF07282.11 KSA01890.1 - 9.3 6.3 8.0 30 4.6 2.5 2.7 2 1 0 2 2 2 0 Putative transposase DNA-binding domain HEAT_2 PF13646.6 KSA01891.1 - 8.1e-29 99.9 4.4 3.6e-14 52.9 0.1 3.3 3 1 1 4 4 4 2 HEAT repeats HEAT_PBS PF03130.16 KSA01891.1 - 4.1e-21 73.4 0.7 2.9e-05 24.3 0.0 6.5 8 0 0 8 8 8 5 PBS lyase HEAT-like repeat HEAT PF02985.22 KSA01891.1 - 3.1e-12 45.6 1.3 0.018 15.3 0.0 5.8 7 0 0 7 7 7 3 HEAT repeat HEAT_EZ PF13513.6 KSA01891.1 - 1.3e-10 41.6 0.8 0.18 12.4 0.1 4.8 4 1 0 4 4 4 4 HEAT-like repeat DUF3385 PF11865.8 KSA01891.1 - 0.055 13.4 0.0 5.3 6.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3385) Cnd1 PF12717.7 KSA01891.1 - 0.32 11.0 4.0 3 7.9 0.1 3.5 2 2 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Cpn60_TCP1 PF00118.24 KSA01892.1 - 1.3e-155 518.8 5.6 1.5e-155 518.6 5.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cation_ATPase PF13246.6 KSA01892.1 - 0.011 15.8 0.0 0.049 13.7 0.0 2.0 2 0 0 2 2 2 0 Cation transport ATPase (P-type) Actin PF00022.19 KSA01893.1 - 4.3e-92 308.8 0.0 3.9e-55 187.1 0.0 2.0 1 1 1 2 2 2 2 Actin FtsA PF14450.6 KSA01893.1 - 0.0049 17.3 0.0 0.013 15.9 0.0 1.7 2 1 0 2 2 2 1 Cell division protein FtsA MreB_Mbl PF06723.13 KSA01893.1 - 0.0063 15.4 0.0 0.26 10.1 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FAT PF02259.23 KSA01894.1 - 1.6e-143 478.1 1.7 1.6e-143 478.1 1.7 2.2 2 0 0 2 2 2 1 FAT domain DUF3385 PF11865.8 KSA01894.1 - 5.7e-72 240.9 9.5 2.1e-63 213.0 0.2 7.2 5 2 1 6 6 6 2 Domain of unknown function (DUF3385) PI3_PI4_kinase PF00454.27 KSA01894.1 - 8.9e-71 238.6 0.0 2.1e-70 237.4 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FRB_dom PF08771.11 KSA01894.1 - 3e-43 146.3 3.0 9.4e-43 144.7 0.7 3.1 3 0 0 3 3 3 1 FKBP12-rapamycin binding domain FATC PF02260.20 KSA01894.1 - 8.5e-17 60.7 0.3 1.9e-16 59.5 0.3 1.7 1 0 0 1 1 1 1 FATC domain HEAT PF02985.22 KSA01894.1 - 6.5e-13 47.7 3.3 0.0069 16.6 0.0 8.1 7 0 0 7 7 6 3 HEAT repeat HEAT_EZ PF13513.6 KSA01894.1 - 6.4e-12 45.7 17.1 4.6e-05 23.8 0.0 9.7 9 1 1 10 10 9 3 HEAT-like repeat HEAT_2 PF13646.6 KSA01894.1 - 1.2e-11 44.8 3.9 0.019 15.3 0.0 7.3 7 1 1 8 8 7 3 HEAT repeats IFRD PF05004.13 KSA01894.1 - 9.2e-06 25.0 3.4 0.029 13.5 0.0 4.1 4 0 0 4 4 4 2 Interferon-related developmental regulator (IFRD) Cnd1 PF12717.7 KSA01894.1 - 3.7e-05 23.8 2.6 0.48 10.4 0.1 5.3 4 1 2 6 6 6 2 non-SMC mitotic condensation complex subunit 1 Cnd3 PF12719.7 KSA01894.1 - 0.00023 20.5 1.2 0.0041 16.3 0.1 3.3 2 1 1 3 3 3 1 Nuclear condensing complex subunits, C-term domain TPR_19 PF14559.6 KSA01894.1 - 0.0019 18.7 0.1 7.3 7.2 0.0 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF3437 PF11919.8 KSA01894.1 - 0.0037 17.2 0.0 0.83 9.6 0.0 3.9 3 0 0 3 3 3 1 Domain of unknown function (DUF3437) Vac14_Fab1_bd PF12755.7 KSA01894.1 - 0.0099 16.5 2.0 69 4.1 0.0 6.4 5 1 3 8 8 7 0 Vacuolar 14 Fab1-binding region TPR_14 PF13428.6 KSA01894.1 - 0.072 13.9 0.1 6.7 7.8 0.0 3.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 KSA01894.1 - 0.091 13.4 0.4 2.9 8.6 0.0 3.5 4 0 0 4 4 3 0 Tetratricopeptide repeat TrmO_C PF18389.1 KSA01894.1 - 0.11 12.6 0.0 0.33 11.1 0.0 1.9 1 0 0 1 1 1 0 TrmO C-terminal domain RICTOR_V PF14668.6 KSA01894.1 - 0.19 12.0 0.5 15 5.9 0.0 4.0 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR, domain 5 Hormone_3 PF00159.18 KSA01894.1 - 0.46 10.6 1.7 2.4 8.3 1.1 2.5 1 1 1 2 2 2 0 Pancreatic hormone peptide RTC PF01137.21 KSA01895.1 - 1.9e-41 141.7 0.0 2.5e-41 141.3 0.0 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 KSA01895.1 - 2.2e-30 105.2 0.0 3.4e-30 104.6 0.0 1.3 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain HTH_Tnp_ISL3 PF13542.6 KSA01895.1 - 0.012 15.1 0.0 0.021 14.2 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 TAF4 PF05236.14 KSA01896.1 - 3.4e-74 250.1 8.3 6.3e-74 249.2 8.3 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family Cnd1_N PF12922.7 KSA01897.1 - 8.3e-46 155.9 0.7 8.3e-46 155.9 0.7 1.8 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT PF02985.22 KSA01897.1 - 1.3e-07 31.2 1.4 0.0056 16.8 0.0 3.6 3 0 0 3 3 3 2 HEAT repeat HEAT_2 PF13646.6 KSA01897.1 - 2.2e-05 24.8 0.0 0.00039 20.8 0.0 2.5 2 0 0 2 2 2 1 HEAT repeats Cnd1 PF12717.7 KSA01897.1 - 5.1e-05 23.4 4.0 8.2e-05 22.7 0.3 3.0 2 2 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 KSA01897.1 - 0.0004 20.5 0.1 0.017 15.3 0.0 2.5 1 1 1 2 2 2 2 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 KSA01897.1 - 0.00093 19.7 0.4 4.9 7.8 0.0 3.3 3 0 0 3 3 3 2 HEAT-like repeat Roughex PF06020.11 KSA01897.1 - 1.4 7.9 9.2 2.3 7.3 9.2 1.2 1 0 0 1 1 1 0 Drosophila roughex protein PBP1_TM PF14812.6 KSA01897.1 - 5.6 7.4 9.6 13 6.2 9.6 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Cnd1 PF12717.7 KSA01898.1 - 1.7e-43 148.5 2.3 4e-42 144.0 0.8 2.7 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Cnd3 PF12719.7 KSA01898.1 - 2e-06 27.2 1.2 1e-05 24.9 1.2 2.2 1 1 0 1 1 1 1 Nuclear condensing complex subunits, C-term domain HEAT PF02985.22 KSA01898.1 - 0.0012 18.9 0.5 0.2 12.0 0.0 3.7 3 0 0 3 3 3 1 HEAT repeat HEAT_2 PF13646.6 KSA01898.1 - 0.0027 18.1 0.0 0.024 15.0 0.0 2.5 2 0 0 2 2 2 1 HEAT repeats HEAT_EZ PF13513.6 KSA01898.1 - 0.035 14.6 0.1 3 8.4 0.0 3.4 4 0 0 4 4 4 0 HEAT-like repeat YtzH PF14165.6 KSA01898.1 - 0.2 12.0 3.0 0.27 11.7 0.0 2.7 3 0 0 3 3 3 0 YtzH-like protein AKAP7_RIRII_bdg PF10470.9 KSA01898.1 - 0.65 10.1 3.7 1.4 9.0 3.7 1.5 1 0 0 1 1 1 0 PKA-RI-RII subunit binding domain of A-kinase anchor protein MBOAT PF03062.19 KSA01899.1 - 5.8e-65 219.9 7.1 1e-64 219.1 7.1 1.4 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Apo-CIII PF05778.12 KSA01899.1 - 0.17 11.5 0.2 4.8 6.9 0.1 2.7 1 1 1 2 2 2 0 Apolipoprotein CIII (Apo-CIII) Ferrochelatase PF00762.19 KSA01900.1 - 2.9e-103 345.3 0.0 3.3e-103 345.1 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase Med4 PF10018.9 KSA01901.1 - 4.7e-30 104.7 0.9 6.7e-30 104.2 0.2 1.6 2 0 0 2 2 2 1 Vitamin-D-receptor interacting Mediator subunit 4 DUF4187 PF13821.6 KSA01902.1 - 2.7e-18 65.5 3.4 7.1e-18 64.1 3.4 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.23 KSA01902.1 - 1.7e-07 31.0 0.2 3.3e-07 30.1 0.2 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KSA01902.1 - 0.0035 17.4 0.0 0.012 15.6 0.0 1.9 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.22 KSA01903.1 - 2.8e-31 107.1 0.2 7.5e-14 51.3 0.1 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KSA01903.1 - 0.00021 21.4 0.3 0.32 11.1 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif Nup35_RRM_2 PF14605.6 KSA01903.1 - 0.014 15.4 0.1 0.051 13.6 0.0 2.1 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Pkinase PF00069.25 KSA01904.1 - 4.5e-57 193.4 0.7 2.1e-56 191.2 0.7 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KSA01904.1 - 4.9e-33 114.5 0.0 1.4e-32 113.0 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 KSA01904.1 - 2.1e-12 47.2 0.6 1.4e-10 41.4 0.0 3.2 3 0 0 3 3 3 1 FHA domain Haspin_kinase PF12330.8 KSA01904.1 - 3.8e-05 22.8 0.5 7.4e-05 21.8 0.5 1.5 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KSA01904.1 - 0.00044 19.1 0.1 0.00074 18.4 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KSA01904.1 - 0.028 13.8 0.0 0.078 12.3 0.0 1.8 2 0 0 2 2 2 0 Kinase-like APH PF01636.23 KSA01904.1 - 0.067 13.1 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family NDUF_B8 PF05821.11 KSA01906.1 - 3.1e-06 27.1 0.2 4.7e-06 26.6 0.2 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) SNF2_N PF00176.23 KSA01907.1 - 4.1e-66 223.1 0.1 1e-65 221.8 0.1 1.7 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KSA01907.1 - 6.6e-20 71.5 0.2 1.6e-18 67.1 0.0 3.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain HSA PF07529.13 KSA01907.1 - 2.4e-12 47.0 11.3 2.4e-12 47.0 11.3 3.1 2 0 0 2 2 2 1 HSA ResIII PF04851.15 KSA01907.1 - 8.4e-12 45.4 0.0 8.4e-12 45.4 0.0 3.6 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KSA01907.1 - 3.9e-07 30.0 0.0 1.1e-05 25.2 0.0 3.0 3 0 0 3 3 3 1 DEAD/DEAH box helicase CobA_CobO_BtuR PF02572.15 KSA01907.1 - 0.13 12.5 1.4 37 4.5 0.0 4.2 4 0 0 4 4 4 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP Tugs PF17840.1 KSA01907.1 - 2.9 8.2 5.4 1.2 9.4 0.6 2.7 2 0 0 2 2 2 0 Tethering Ubl4a to BAGS domain V-ATPase_G PF03179.15 KSA01908.1 - 8.7e-29 100.1 11.6 9.6e-29 100.0 11.6 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit V-ATPase_G_2 PF16999.5 KSA01908.1 - 0.0017 18.7 10.4 0.0022 18.4 10.4 1.1 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit vATP-synt_E PF01991.18 KSA01908.1 - 0.0052 16.2 10.7 0.0065 15.9 10.7 1.1 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit PilJ PF13675.6 KSA01908.1 - 0.0064 16.5 0.1 0.0076 16.3 0.1 1.1 1 0 0 1 1 1 1 Type IV pili methyl-accepting chemotaxis transducer N-term cwf18 PF08315.12 KSA01908.1 - 0.021 15.5 6.4 0.026 15.2 6.4 1.2 1 0 0 1 1 1 0 cwf18 pre-mRNA splicing factor ATP-synt_B PF00430.18 KSA01908.1 - 0.032 14.3 13.3 0.12 12.5 13.3 1.8 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) DUF3552 PF12072.8 KSA01908.1 - 0.04 13.3 14.6 0.061 12.7 14.6 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) OmpH PF03938.14 KSA01908.1 - 0.13 12.6 10.1 0.19 12.1 10.1 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) SCAB_CC PF16712.5 KSA01908.1 - 0.19 11.6 7.8 4.6 7.0 7.8 2.0 1 1 0 1 1 1 0 Coiled-coil regions of plant-specific actin-binding protein RE_AlwI PF09491.10 KSA01908.1 - 0.2 10.4 8.1 0.42 9.4 8.0 1.5 1 1 0 1 1 1 0 AlwI restriction endonuclease DUF4094 PF13334.6 KSA01908.1 - 1.3 9.5 3.9 1.6 9.2 3.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) DUF4407 PF14362.6 KSA01908.1 - 2.4 7.5 8.5 2.9 7.1 7.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) UPF0242 PF06785.11 KSA01908.1 - 3.1 7.9 9.7 3.3 7.8 8.4 1.3 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus HalX PF08663.10 KSA01908.1 - 5.8 7.3 10.4 24 5.3 0.3 2.6 1 1 1 2 2 2 0 HalX domain Aldedh PF00171.22 KSA01909.1 - 1.9e-122 409.1 0.0 2.4e-122 408.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF3687 PF12459.8 KSA01909.1 - 0.12 11.9 1.6 0.23 11.0 1.6 1.5 1 0 0 1 1 1 0 D-Ala-teichoic acid biosynthesis protein Tcf25 PF04910.14 KSA01910.1 - 1.9e-96 323.2 4.7 2.7e-96 322.7 4.7 1.3 1 0 0 1 1 1 1 Transcriptional repressor TCF25 Ndc1_Nup PF09531.10 KSA01910.1 - 3.3 6.3 9.0 5.5 5.6 9.0 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RhoGEF PF00621.20 KSA01911.1 - 9.9e-18 65.0 5.3 2e-17 64.0 5.3 1.5 1 0 0 1 1 1 1 RhoGEF domain SBDS PF01172.18 KSA01912.1 - 3.3e-20 71.9 0.3 4.4e-20 71.6 0.3 1.0 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein DUF3888 PF13027.6 KSA01913.1 - 0.14 12.6 1.3 0.43 11.0 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3888) AMP-binding PF00501.28 KSA01914.1 - 3.6e-76 256.4 0.0 5.3e-76 255.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme FAD-oxidase_C PF02913.19 KSA01915.1 - 3.1e-59 200.6 0.0 4.6e-59 200.1 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KSA01915.1 - 1.5e-34 118.8 0.0 2.6e-34 117.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain UPF0029 PF01205.19 KSA01916.1 - 1.2e-26 93.1 0.0 1.5e-26 92.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 Septin PF00735.18 KSA01917.1 - 1.2e-78 264.3 1.7 1.2e-78 264.3 1.7 1.6 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 KSA01917.1 - 4.3e-07 30.0 0.0 9.8e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KSA01917.1 - 0.00017 21.5 1.3 0.0014 18.5 0.0 2.6 3 0 0 3 3 3 1 RsgA GTPase ABC_tran PF00005.27 KSA01917.1 - 0.0002 21.9 0.1 0.00063 20.3 0.0 1.9 2 0 0 2 2 2 1 ABC transporter AIG1 PF04548.16 KSA01917.1 - 0.00066 19.1 0.0 0.0017 17.8 0.0 1.7 1 0 0 1 1 1 1 AIG1 family Roc PF08477.13 KSA01917.1 - 0.0041 17.3 0.0 0.0081 16.4 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 KSA01917.1 - 0.011 15.3 0.1 0.053 13.1 0.1 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_29 PF13555.6 KSA01917.1 - 0.014 15.2 0.1 0.029 14.1 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.27 KSA01917.1 - 0.02 14.5 0.3 1.8 8.1 0.1 2.6 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_23 PF13476.6 KSA01917.1 - 0.022 15.3 10.8 0.55 10.7 0.0 2.6 3 0 0 3 3 3 0 AAA domain IIGP PF05049.13 KSA01917.1 - 0.033 13.3 0.2 0.033 13.3 0.2 1.6 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) Ras PF00071.22 KSA01917.1 - 0.1 12.2 0.0 0.3 10.7 0.0 1.8 1 0 0 1 1 1 0 Ras family Dynamin_N PF00350.23 KSA01917.1 - 2.8 8.0 5.6 1.2 9.1 0.3 2.6 2 1 1 3 3 3 0 Dynamin family Coatomer_E PF04733.14 KSA01918.1 - 3.5e-18 66.0 9.2 6.4e-18 65.2 9.2 1.5 1 1 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.6 KSA01918.1 - 0.00074 20.0 3.5 0.063 13.8 0.0 3.7 5 0 0 5 5 5 2 Tetratricopeptide repeat zf-CCCH_6 PF18585.1 KSA01918.1 - 0.17 11.8 0.5 0.42 10.5 0.5 1.6 1 0 0 1 1 1 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 DUF1689 PF07954.11 KSA01919.1 - 1.4e-45 155.3 0.4 2.1e-45 154.7 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1689) DUF2794 PF10984.8 KSA01919.1 - 0.15 12.2 0.1 0.27 11.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2794) tRNA-synt_2b PF00587.25 KSA01920.1 - 2.7e-34 118.7 0.0 5.4e-34 117.7 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KSA01920.1 - 2.3e-15 56.5 2.9 3.1e-15 56.1 1.0 2.2 3 0 0 3 3 3 1 Anticodon binding domain tRNA_SAD PF07973.14 KSA01920.1 - 2.8e-12 46.5 0.0 6.5e-12 45.3 0.0 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.21 KSA01920.1 - 3.8e-11 42.9 0.0 7.2e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 TGS domain MPS2 PF17060.5 KSA01921.1 - 0.013 14.8 2.8 0.39 9.9 2.8 2.0 1 1 0 1 1 1 0 Monopolar spindle protein 2 SlyX PF04102.12 KSA01921.1 - 0.035 14.7 1.9 0.43 11.2 0.1 2.3 1 1 1 2 2 2 0 SlyX DUF892 PF05974.12 KSA01921.1 - 0.046 13.7 0.4 0.087 12.8 0.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF892) Exonuc_VII_L PF02601.15 KSA01921.1 - 0.085 12.4 1.3 0.099 12.2 1.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit BAR_3 PF16746.5 KSA01921.1 - 0.12 12.0 5.5 0.1 12.3 1.1 2.1 1 1 1 2 2 2 0 BAR domain of APPL family TRAPPC-Trs85 PF12739.7 KSA01921.1 - 0.15 11.0 0.6 0.16 10.9 0.6 1.1 1 0 0 1 1 1 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Spc7 PF08317.11 KSA01921.1 - 0.77 8.6 7.0 1.1 8.1 7.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Sec34 PF04136.15 KSA01921.1 - 1 9.2 6.4 3.1 7.7 5.3 2.0 1 1 2 3 3 3 0 Sec34-like family CCDC-167 PF15188.6 KSA01921.1 - 1.4 9.3 5.7 0.71 10.3 1.0 2.5 1 1 2 3 3 3 0 Coiled-coil domain-containing protein 167 Spectrin PF00435.21 KSA01921.1 - 1.6 9.3 6.7 1.7 9.2 1.8 2.4 1 1 1 2 2 2 0 Spectrin repeat Vps52 PF04129.12 KSA01921.1 - 1.9 7.1 6.0 2.2 6.9 0.0 2.3 1 1 2 3 3 3 0 Vps52 / Sac2 family Ribosomal_L14 PF00238.19 KSA01922.1 - 2.7e-47 159.8 0.9 3.1e-47 159.7 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e KRE9 PF05390.11 KSA01923.1 - 1.4e-34 118.9 16.0 1.4e-34 118.9 16.0 1.8 2 0 0 2 2 2 1 Yeast cell wall synthesis protein KRE9/KNH1 GPI-anchored PF10342.9 KSA01923.1 - 4.4e-14 53.0 0.7 4.4e-14 53.0 0.7 2.2 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family PAP1 PF08601.10 KSA01924.1 - 0.097 12.4 11.2 0.11 12.3 11.2 1.0 1 0 0 1 1 1 0 Transcription factor PAP1 Flp_N PF03930.14 KSA01925.1 - 0.12 12.3 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Recombinase Flp protein N-terminus Aldedh PF00171.22 KSA01926.1 - 6.5e-158 526.0 0.0 7.3e-158 525.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Arginase PF00491.21 KSA01927.1 - 1.7e-85 286.9 0.1 2.4e-85 286.5 0.1 1.2 1 0 0 1 1 1 1 Arginase family WSC PF01822.19 KSA01928.1 - 3.2e-08 33.6 13.1 3.2e-08 33.6 13.1 3.1 2 1 0 2 2 2 1 WSC domain DUF2207 PF09972.9 KSA01928.1 - 0.045 12.5 0.0 0.062 12.1 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Utp14 PF04615.13 KSA01928.1 - 0.061 11.9 11.2 0.072 11.7 11.2 1.1 1 0 0 1 1 1 0 Utp14 protein SOG2 PF10428.9 KSA01928.1 - 0.075 12.2 28.7 0.12 11.6 28.7 1.4 1 0 0 1 1 1 0 RAM signalling pathway protein PPP4R2 PF09184.11 KSA01928.1 - 0.082 12.5 16.0 0.12 11.9 16.0 1.3 1 0 0 1 1 1 0 PPP4R2 Hamartin PF04388.12 KSA01928.1 - 0.18 10.4 18.7 0.19 10.4 18.7 1.1 1 0 0 1 1 1 0 Hamartin protein Beta-APP PF03494.13 KSA01928.1 - 0.19 11.6 7.7 0.41 10.5 7.7 1.5 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) DUF4551 PF15087.6 KSA01928.1 - 0.39 9.5 13.7 0.5 9.1 13.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) GREB1 PF15782.5 KSA01928.1 - 1 6.4 20.2 1.2 6.2 20.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF2408 PF10303.9 KSA01929.1 - 6e-46 156.4 25.2 1.7e-35 122.5 0.6 5.6 3 2 1 5 5 5 4 Protein of unknown function (DUF2408) Takusan PF04822.13 KSA01929.1 - 0.048 13.5 0.4 0.048 13.5 0.4 4.6 4 1 2 6 6 6 0 Takusan AAA_lid_9 PF17871.1 KSA01929.1 - 0.097 12.6 3.9 3.2 7.7 0.0 3.9 4 0 0 4 4 4 0 AAA lid domain DUF5629 PF18629.1 KSA01929.1 - 4.2 8.0 6.4 2 9.0 1.3 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5629) Cut8 PF08559.10 KSA01930.1 - 1e-82 277.4 11.2 1.3e-82 277.0 11.2 1.1 1 0 0 1 1 1 1 Cut8, nuclear proteasome tether protein PMAIP1 PF15150.6 KSA01930.1 - 0.079 12.8 0.0 0.079 12.8 0.0 2.1 3 0 0 3 3 3 0 Phorbol-12-myristate-13-acetate-induced DUF99 PF01949.16 KSA01931.1 - 0.0076 15.7 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function DUF99 BING4CT PF08149.11 KSA01932.1 - 3.7e-37 126.0 0.8 2e-35 120.5 0.0 3.4 4 0 0 4 4 4 1 BING4CT (NUC141) domain ANAPC4_WD40 PF12894.7 KSA01932.1 - 1.3e-06 28.6 0.0 2.9 8.3 0.0 5.1 3 1 4 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KSA01932.1 - 1.1e-05 26.1 4.5 0.00071 20.3 0.0 4.9 5 1 0 5 5 5 1 WD domain, G-beta repeat WD40_like PF17005.5 KSA01932.1 - 0.23 10.8 0.0 2 7.7 0.0 2.0 2 0 0 2 2 2 0 WD40-like domain DHO_dh PF01180.21 KSA01933.1 - 1.9e-95 319.5 0.0 2.4e-95 319.1 0.0 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase DASH_Dam1 PF08653.10 KSA01934.1 - 2.8e-26 91.1 0.3 4.9e-26 90.3 0.3 1.4 1 0 0 1 1 1 1 DASH complex subunit Dam1 TSC22 PF01166.18 KSA01934.1 - 0.0023 18.2 3.3 0.0023 18.2 3.3 1.8 2 0 0 2 2 2 1 TSC-22/dip/bun family ORF6C PF10552.9 KSA01934.1 - 0.14 12.3 1.3 0.28 11.3 1.3 1.4 1 0 0 1 1 1 0 ORF6C domain DUF1863 PF08937.11 KSA01935.1 - 0.026 14.8 0.1 0.026 14.8 0.1 1.0 1 0 0 1 1 1 0 MTH538 TIR-like domain (DUF1863) GET2 PF08690.10 KSA01936.1 - 1.5e-92 310.6 0.0 1.8e-92 310.3 0.0 1.0 1 0 0 1 1 1 1 GET complex subunit GET2 DUF4175 PF13779.6 KSA01936.1 - 0.055 11.4 0.2 0.079 10.9 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF4248 PF14053.6 KSA01936.1 - 0.12 12.5 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4248) DRIM PF07539.12 KSA01936.1 - 0.14 10.5 0.8 0.2 9.9 0.1 1.5 2 0 0 2 2 2 0 Down-regulated in metastasis MCU PF04678.13 KSA01936.1 - 0.27 11.3 2.6 5.3 7.1 0.0 2.6 2 0 0 2 2 2 0 Mitochondrial calcium uniporter SURF1 PF02104.15 KSA01937.1 - 6e-41 140.6 0.0 8.9e-41 140.1 0.0 1.2 1 0 0 1 1 1 1 SURF1 family Motilin_ghrelin PF04644.12 KSA01937.1 - 0.15 11.9 0.5 0.33 10.8 0.5 1.5 1 0 0 1 1 1 0 Motilin/ghrelin Med10 PF09748.9 KSA01939.1 - 1.7e-37 128.0 0.0 2e-37 127.8 0.0 1.0 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex S10_plectin PF03501.15 KSA01939.1 - 0.16 12.0 0.0 0.25 11.5 0.0 1.3 1 0 0 1 1 1 0 Plectin/S10 domain DUF5326 PF17260.2 KSA01941.1 - 0.4 10.9 5.3 5.7 7.1 0.3 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5326) CMD PF02627.20 KSA01942.1 - 1.7e-05 24.8 0.0 0.00085 19.3 0.0 2.3 2 0 0 2 2 2 2 Carboxymuconolactone decarboxylase family AFG1_ATPase PF03969.16 KSA01943.1 - 6.4e-59 199.7 2.0 1.8e-56 191.6 0.4 3.5 2 1 1 3 3 3 1 AFG1-like ATPase NB-ARC PF00931.22 KSA01943.1 - 0.00099 18.4 0.2 0.0022 17.2 0.1 1.6 2 0 0 2 2 2 1 NB-ARC domain NACHT PF05729.12 KSA01943.1 - 0.014 15.3 0.0 0.026 14.4 0.0 1.4 1 0 0 1 1 1 0 NACHT domain TMC PF07810.13 KSA01943.1 - 0.024 15.2 0.1 0.064 13.8 0.1 1.7 1 0 0 1 1 1 0 TMC domain AAA_22 PF13401.6 KSA01943.1 - 0.025 14.8 0.0 0.082 13.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KSA01943.1 - 0.03 14.9 0.2 4.2 7.9 0.0 3.2 2 1 1 3 3 3 0 ABC transporter RNA_helicase PF00910.22 KSA01943.1 - 0.1 13.0 0.2 0.75 10.2 0.0 2.4 2 0 0 2 2 2 0 RNA helicase GST_C PF00043.25 KSA01943.1 - 0.12 12.6 0.0 0.29 11.4 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain AAA_29 PF13555.6 KSA01943.1 - 0.13 12.0 0.0 0.33 10.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 KSA01943.1 - 0.18 12.2 0.0 0.52 10.7 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain Myotub-related PF06602.14 KSA01944.1 - 2.5e-141 470.7 4.1 3.1e-141 470.4 4.1 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.6 KSA01944.1 - 0.0062 16.5 0.0 0.016 15.2 0.0 1.7 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 KSA01944.1 - 0.026 14.1 0.0 0.053 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DSPc PF00782.20 KSA01944.1 - 0.1 12.4 0.2 0.33 10.8 0.0 2.0 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain MID_MedPIWI PF18296.1 KSA01944.1 - 3 7.6 6.8 0.67 9.7 0.2 2.7 2 1 0 2 2 2 0 MID domain of medPIWI WD40 PF00400.32 KSA01945.1 - 0.54 11.2 4.6 0.61 11.0 0.0 3.5 5 0 0 5 5 5 0 WD domain, G-beta repeat EMC3_TMCO1 PF01956.16 KSA01945.1 - 0.62 9.8 7.4 1.2 8.8 7.4 1.4 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Oxysterol_BP PF01237.18 KSA01946.1 - 8.3e-132 439.5 0.1 1.8e-131 438.4 0.1 1.6 1 0 0 1 1 1 1 Oxysterol-binding protein Ank_2 PF12796.7 KSA01946.1 - 2.1e-14 53.8 0.1 2.9e-09 37.4 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KSA01946.1 - 7.8e-14 51.9 0.1 1.8e-09 37.9 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KSA01946.1 - 2.2e-13 49.0 0.1 0.0003 21.0 0.0 4.6 3 1 1 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 KSA01946.1 - 2.5e-11 43.6 0.0 0.0002 21.6 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeats (many copies) PH PF00169.29 KSA01946.1 - 2.7e-09 37.5 0.2 8.1e-09 35.9 0.2 1.9 1 0 0 1 1 1 1 PH domain Ank PF00023.30 KSA01946.1 - 6.8e-09 35.8 0.1 0.00029 21.1 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat PH_8 PF15409.6 KSA01946.1 - 1.2e-07 31.9 0.3 3.1e-07 30.6 0.3 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 KSA01946.1 - 0.057 13.8 1.2 0.52 10.8 1.2 2.8 1 1 0 1 1 1 0 Pleckstrin homology domain RRM_1 PF00076.22 KSA01947.1 - 2.1e-10 40.3 0.0 3.7e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KSA01947.1 - 1.3e-06 28.0 0.2 1.4e-06 27.9 0.2 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KSA01947.1 - 0.00066 19.5 0.0 0.00096 19.0 0.0 1.2 1 0 0 1 1 1 1 Occluded RNA-recognition motif Limkain-b1 PF11608.8 KSA01947.1 - 0.017 15.2 0.0 0.025 14.7 0.0 1.4 1 1 0 1 1 1 0 Limkain b1 DUF4523 PF15023.6 KSA01947.1 - 0.051 13.4 0.0 0.056 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4523) Amino_oxidase PF01593.24 KSA01948.1 - 1.2e-18 67.7 0.0 1.3e-18 67.6 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KSA01948.1 - 2.9e-11 43.4 0.0 7.5e-11 42.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KSA01948.1 - 1.8e-05 24.1 0.0 3.9e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 KSA01948.1 - 6.9e-05 23.3 0.0 0.039 14.5 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KSA01948.1 - 7.6e-05 22.4 0.0 0.00045 19.9 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Mqo PF06039.15 KSA01948.1 - 0.00094 17.8 0.0 0.018 13.6 0.0 2.3 2 0 0 2 2 2 1 Malate:quinone oxidoreductase (Mqo) Pyr_redox_2 PF07992.14 KSA01948.1 - 0.011 15.0 0.0 0.061 12.5 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KSA01948.1 - 0.11 12.5 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Arrestin_C PF02752.22 KSA01949.1 - 6.4e-08 33.1 7.9 3e-06 27.7 6.5 3.4 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain adh_short_C2 PF13561.6 KSA01951.1 - 2.1e-49 168.2 0.0 2.6e-49 167.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KSA01951.1 - 6e-47 159.6 0.2 7.2e-47 159.4 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KSA01951.1 - 4.8e-17 62.4 0.1 7.1e-17 61.9 0.1 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KSA01951.1 - 4.1e-05 22.9 0.1 5.5e-05 22.4 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KSA01951.1 - 0.0044 16.5 0.0 0.0067 15.9 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 KSA01951.1 - 0.0054 16.1 0.2 0.011 15.1 0.2 1.4 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) GDP_Man_Dehyd PF16363.5 KSA01951.1 - 0.024 14.0 0.0 0.036 13.4 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Kinesin PF00225.23 KSA01952.1 - 7.5e-109 363.7 5.8 7.5e-109 363.7 5.8 1.7 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KSA01952.1 - 2.5e-29 102.1 1.8 5.7e-29 101.0 0.4 2.3 2 0 0 2 2 2 1 Microtubule binding RWD PF05773.22 KSA01952.1 - 9.1 6.6 9.2 0.39 11.0 1.9 2.6 3 0 0 3 3 3 0 RWD domain 2-Hacid_dh_C PF02826.19 KSA01953.1 - 4.8e-54 182.4 0.0 8.8e-54 181.6 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KSA01953.1 - 2.2e-39 134.2 0.1 3.7e-39 133.5 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KSA01953.1 - 3e-06 27.5 1.6 6.3e-06 26.4 0.7 2.1 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 KSA01953.1 - 5.5e-06 26.5 0.1 1.1e-05 25.5 0.1 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ACT PF01842.25 KSA01953.1 - 3.9e-05 23.3 0.0 0.00012 21.8 0.0 1.8 1 0 0 1 1 1 1 ACT domain IlvN PF07991.12 KSA01953.1 - 0.00053 19.6 0.7 0.001 18.7 0.2 1.7 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain XdhC_C PF13478.6 KSA01953.1 - 0.0064 17.0 0.1 0.024 15.1 0.1 2.0 2 0 0 2 2 2 1 XdhC Rossmann domain Rossmann-like PF10727.9 KSA01953.1 - 0.035 14.0 0.4 0.2 11.5 0.4 2.1 1 1 0 1 1 1 0 Rossmann-like domain DpaA_N PF16924.5 KSA01953.1 - 0.068 13.3 0.1 2.5 8.2 0.0 2.9 2 1 0 2 2 2 0 Dipicolinate synthase subunit A N-terminal domain 3HCDH_N PF02737.18 KSA01953.1 - 0.11 12.4 2.0 0.46 10.3 0.4 2.4 2 1 1 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TPR_8 PF13181.6 KSA01954.1 - 0.011 15.9 1.6 3.3 8.1 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Utp13 PF08625.11 KSA01954.1 - 0.054 13.4 1.3 0.15 12.0 0.5 2.1 1 1 1 2 2 2 0 Utp13 specific WD40 associated domain DNA_alkylation PF08713.11 KSA01954.1 - 0.06 13.0 0.2 0.77 9.4 0.0 2.3 2 0 0 2 2 2 0 DNA alkylation repair enzyme Telomere_reg-2 PF10193.9 KSA01954.1 - 0.34 11.4 7.9 16 6.0 0.4 3.8 3 1 1 4 4 4 0 Telomere length regulation protein RPN2_C PF18004.1 KSA01955.1 - 1.5e-57 194.0 12.3 2.4e-57 193.3 12.3 1.3 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 KSA01955.1 - 4.6e-33 112.0 13.5 2.2e-07 31.0 0.2 6.5 6 0 0 6 6 6 6 Proteasome/cyclosome repeat HEAT_2 PF13646.6 KSA01955.1 - 7.2e-16 58.4 0.0 3.6e-14 52.9 0.0 2.5 2 0 0 2 2 2 1 HEAT repeats HEAT PF02985.22 KSA01955.1 - 2.4e-06 27.3 0.0 1.1 9.6 0.0 3.6 3 0 0 3 3 3 2 HEAT repeat HEAT_EZ PF13513.6 KSA01955.1 - 0.00084 19.8 0.0 4.7 7.8 0.0 3.6 2 1 1 3 3 3 3 HEAT-like repeat SAPS PF04499.15 KSA01955.1 - 0.019 13.8 0.1 0.026 13.3 0.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Exo_endo_phos PF03372.23 KSA01956.1 - 0.0014 18.2 0.0 0.0096 15.5 0.0 2.1 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family ATP13 PF12921.7 KSA01957.1 - 0.0077 16.1 1.0 0.16 11.9 0.1 3.1 2 1 1 3 3 3 1 Mitochondrial ATPase expression TPR_12 PF13424.6 KSA01957.1 - 0.076 13.3 0.2 29 5.1 0.0 3.6 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 KSA01957.1 - 0.75 10.1 11.3 33 4.9 1.6 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat SUI1 PF01253.22 KSA01958.1 - 1.9e-22 79.6 2.3 1.9e-22 79.6 2.3 1.9 1 1 0 1 1 1 1 Translation initiation factor SUI1 Img2 PF05046.14 KSA01958.1 - 0.054 13.8 2.7 0.84 10.0 2.6 2.4 1 1 0 1 1 1 0 Mitochondrial large subunit ribosomal protein (Img2) CpeS PF09367.10 KSA01958.1 - 0.17 11.8 2.4 0.23 11.4 2.4 1.3 1 0 0 1 1 1 0 CpeS-like protein DUF1053 PF06327.14 KSA01958.1 - 1.6 9.3 8.9 0.17 12.4 3.0 2.0 1 1 0 2 2 2 0 Domain of Unknown Function (DUF1053) Cgr1 PF03879.14 KSA01958.1 - 4.9 7.6 21.8 0.055 13.9 9.8 2.3 2 0 0 2 2 2 0 Cgr1 family DUF1788 PF08747.11 KSA01958.1 - 6 6.9 8.4 0.58 10.2 2.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1788) Zn_clus PF00172.18 KSA01959.1 - 3.2e-08 33.6 6.1 5.1e-08 32.9 6.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AAA_16 PF13191.6 KSA01960.1 - 6.1e-07 30.0 0.2 9.5e-06 26.1 0.1 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KSA01960.1 - 0.00051 20.3 0.0 0.0012 19.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KSA01960.1 - 0.015 15.7 0.0 0.039 14.4 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KSA01960.1 - 0.025 14.6 0.0 0.45 10.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) HECT PF00632.25 KSA01961.1 - 1.4e-83 280.9 3.5 1.4e-83 280.9 3.5 2.0 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) SBDS_C PF09377.10 KSA01961.1 - 0.0091 16.0 0.1 0.086 12.9 0.0 2.6 3 0 0 3 3 3 1 SBDS protein C-terminal domain Hydrolase_6 PF13344.6 KSA01962.1 - 2.9e-26 91.5 0.0 6.4e-26 90.4 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KSA01962.1 - 5.4e-10 39.2 0.0 1.7e-09 37.6 0.0 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 KSA01962.1 - 1.5e-09 38.4 0.0 3.4e-09 37.3 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KSA01962.1 - 4.3e-08 33.5 1.4 0.0003 20.9 0.0 3.0 2 2 1 3 3 3 2 Haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.14 KSA01962.1 - 0.025 14.2 0.0 0.045 13.3 0.0 1.3 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) Thr_dehydrat_C PF00585.18 KSA01963.1 - 0.032 14.0 0.1 0.065 13.0 0.1 1.5 1 0 0 1 1 1 0 C-terminal regulatory domain of Threonine dehydratase Rpp20 PF12328.8 KSA01964.1 - 1.3e-32 112.6 0.6 2.1e-32 112.0 0.6 1.3 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.21 KSA01964.1 - 4.7e-10 39.1 0.8 8e-10 38.4 0.8 1.4 1 0 0 1 1 1 1 Alba PolyA_pol PF01743.20 KSA01965.1 - 0.14 12.6 0.9 0.19 12.1 0.9 1.1 1 0 0 1 1 1 0 Poly A polymerase head domain Ribosomal_L24e PF01246.20 KSA01966.1 - 2.2e-30 104.7 2.5 6.4e-30 103.2 2.5 1.8 1 0 0 1 1 1 1 Ribosomal protein L24e Pyr_redox_2 PF07992.14 KSA01967.1 - 7.4e-26 91.0 0.3 4.3e-25 88.6 0.3 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KSA01967.1 - 5.8e-09 35.6 1.8 7.5e-06 25.4 0.3 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KSA01967.1 - 2e-05 23.8 0.0 0.0014 17.8 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 KSA01967.1 - 0.00072 18.7 7.8 0.35 9.9 0.2 3.8 4 0 0 4 4 4 2 Glucose inhibited division protein A HI0933_like PF03486.14 KSA01967.1 - 0.012 14.3 1.4 0.014 14.1 0.2 1.7 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox PF00070.27 KSA01967.1 - 0.04 14.5 0.4 1.4 9.6 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KSA01967.1 - 0.093 13.0 0.2 0.37 11.1 0.3 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Cons_hypoth95 PF03602.15 KSA01967.1 - 0.11 12.1 0.0 0.43 10.2 0.0 1.9 2 0 0 2 2 2 0 Conserved hypothetical protein 95 FAD_oxidored PF12831.7 KSA01967.1 - 0.17 11.2 2.3 0.35 10.1 2.3 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KSA01967.1 - 0.27 10.3 0.6 1.7 7.6 0.6 2.0 1 1 1 2 2 2 0 Lycopene cyclase protein zinc_ribbon_5 PF13719.6 KSA01967.1 - 0.3 10.9 1.4 0.41 10.4 0.1 2.0 2 0 0 2 2 2 0 zinc-ribbon domain Pam16 PF03656.13 KSA01968.1 - 4.1e-07 30.1 0.1 5.6e-07 29.6 0.1 1.3 1 0 0 1 1 1 1 Pam16 DnaJ PF00226.31 KSA01968.1 - 3.1e-05 24.0 0.3 7e-05 22.9 0.1 1.7 2 0 0 2 2 2 1 DnaJ domain DUF2369 PF10179.9 KSA01968.1 - 0.13 12.6 1.1 0.33 11.3 0.0 1.9 2 1 0 2 2 2 0 Uncharacterised conserved protein (DUF2369) ANTH PF07651.16 KSA01969.1 - 9e-62 208.6 3.2 9e-62 208.6 3.2 2.3 2 0 0 2 2 2 1 ANTH domain ENTH PF01417.20 KSA01969.1 - 1.1e-06 28.7 0.5 1.1e-06 28.7 0.5 2.3 2 1 0 2 2 2 1 ENTH domain VIT1 PF01988.19 KSA01969.1 - 7 6.4 6.8 5.8 6.7 4.4 2.0 2 0 0 2 2 2 0 VIT family NmrA PF05368.13 KSA01970.1 - 5.7e-52 176.6 0.1 7e-52 176.3 0.1 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KSA01970.1 - 8.2e-13 48.6 0.0 1.1e-12 48.2 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KSA01970.1 - 6.2e-06 25.4 0.0 8.6e-06 24.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KSA01970.1 - 6.9e-05 22.4 0.0 0.00011 21.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 KSA01970.1 - 0.042 14.3 0.0 0.09 13.2 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Ldh_1_N PF00056.23 KSA01970.1 - 0.049 13.7 0.0 0.085 13.0 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Glyco_hydro_16 PF00722.21 KSA01972.1 - 5.3e-50 169.3 2.1 5.3e-50 169.3 2.1 2.4 2 1 0 2 2 2 1 Glycosyl hydrolases family 16 RIFIN PF02009.16 KSA01972.1 - 2.7 7.8 7.6 3.8 7.3 7.6 1.2 1 0 0 1 1 1 0 Rifin Plasmodium_Vir PF05795.11 KSA01972.1 - 3.1 7.1 14.1 4.9 6.5 14.1 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF1387 PF07139.11 KSA01972.1 - 3.8 7.1 19.6 6.4 6.4 19.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) GREB1 PF15782.5 KSA01972.1 - 4.7 4.2 17.2 5.5 4.0 17.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Presenilin PF01080.17 KSA01972.1 - 7.9 5.1 13.5 12 4.6 13.5 1.3 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 KSA01972.1 - 9.7 5.9 9.1 17 5.1 9.1 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Rhodanese PF00581.20 KSA01973.1 - 3.1e-08 34.1 0.0 3.9e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain CTP_transf_like PF01467.26 KSA01974.1 - 8.8e-34 116.7 0.0 1.6e-33 115.9 0.0 1.5 1 0 0 1 1 1 1 Cytidylyltransferase-like FAD_syn PF06574.12 KSA01974.1 - 0.16 11.9 0.0 0.39 10.6 0.0 1.6 1 0 0 1 1 1 0 FAD synthetase MMM1 PF10296.9 KSA01975.1 - 4.2e-145 482.9 6.8 1.3e-144 481.3 6.8 1.7 1 1 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 Coilin_N PF15862.5 KSA01975.1 - 0.022 14.6 2.4 0.06 13.2 2.4 1.7 1 0 0 1 1 1 0 Coilin N-terminus ApeA_NTD1 PF18862.1 KSA01975.1 - 0.19 11.3 9.2 1.5 8.3 1.1 2.2 2 0 0 2 2 2 0 ApeA N-terminal domain 1 Adaptin_N PF01602.20 KSA01976.1 - 1.2e-91 307.9 14.1 1.5e-91 307.6 14.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KSA01976.1 - 4.6e-16 59.3 0.5 1e-14 54.9 0.0 3.1 1 1 1 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KSA01976.1 - 2.8e-07 30.8 0.4 3.4e-06 27.4 0.1 3.1 4 1 0 4 4 4 1 HEAT repeats HEAT PF02985.22 KSA01976.1 - 0.0001 22.3 0.0 0.31 11.4 0.0 4.5 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.6 KSA01976.1 - 0.013 16.0 0.8 2.2 8.9 0.0 3.6 3 1 1 4 4 4 0 HEAT-like repeat BUD22 PF09073.10 KSA01976.1 - 0.19 11.0 17.3 0.3 10.4 17.3 1.3 1 0 0 1 1 1 0 BUD22 PAF PF15715.5 KSA01976.1 - 7.5 7.1 13.7 15 6.1 13.7 1.5 1 0 0 1 1 1 0 PCNA-associated factor histone like domain XPG_N PF00752.17 KSA01977.1 - 3.9e-35 120.3 0.0 1.4e-34 118.6 0.0 2.1 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 KSA01977.1 - 2.2e-26 92.0 0.0 2.2e-26 92.0 0.0 3.4 2 0 0 2 2 2 1 XPG I-region 5_3_exonuc PF01367.20 KSA01977.1 - 4.8e-05 23.9 0.0 0.00045 20.8 0.0 2.8 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.6 KSA01977.1 - 0.0044 17.6 0.0 0.016 15.8 0.0 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix domain Transposase_20 PF02371.16 KSA01977.1 - 0.049 14.0 0.0 0.099 13.0 0.0 1.4 1 0 0 1 1 1 0 Transposase IS116/IS110/IS902 family HEAT PF02985.22 KSA01979.1 - 3.8e-12 45.4 4.2 0.82 10.1 0.0 8.9 8 0 0 8 8 8 3 HEAT repeat HEAT_2 PF13646.6 KSA01979.1 - 2.7e-08 34.1 0.3 2.4 8.6 0.0 7.2 4 2 7 11 11 11 2 HEAT repeats HEAT_EZ PF13513.6 KSA01979.1 - 2e-07 31.4 0.0 1 10.0 0.0 5.9 6 0 0 6 6 6 2 HEAT-like repeat MMS19_C PF12460.8 KSA01979.1 - 3.5e-05 23.1 12.6 0.0047 16.1 0.0 4.2 3 1 1 4 4 4 2 RNAPII transcription regulator C-terminal NUC173 PF08161.12 KSA01979.1 - 0.0067 16.1 0.6 0.95 9.1 0.0 4.0 4 1 1 5 5 5 1 NUC173 domain Vac14_Fab1_bd PF12755.7 KSA01979.1 - 0.0077 16.8 4.2 3.6 8.2 0.0 5.9 6 2 1 7 7 7 1 Vacuolar 14 Fab1-binding region DUF1440 PF07274.12 KSA01979.1 - 0.019 15.3 0.0 0.16 12.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1440) DUF5413 PF17434.2 KSA01979.1 - 0.11 12.8 0.1 5.8 7.3 0.0 3.3 2 1 1 3 3 3 0 Family of unknown function (DUF5413) DUF1981 PF09324.10 KSA01979.1 - 0.34 10.8 6.1 0.52 10.2 0.2 4.0 4 1 1 5 5 5 0 Domain of unknown function (DUF1981) Elong_Iki1 PF10483.9 KSA01980.1 - 7.2e-82 275.2 1.4 8.1e-82 275.1 1.4 1.0 1 0 0 1 1 1 1 Elongator subunit Iki1 DUF4469 PF14734.6 KSA01980.1 - 0.092 12.9 0.0 0.29 11.3 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4469) with IG-like fold Gpi16 PF04113.14 KSA01981.1 - 3.1e-215 715.9 0.0 3.7e-215 715.6 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component Mad3_BUB1_I PF08311.12 KSA01982.1 - 2.2e-47 160.1 1.3 4.7e-47 159.0 1.3 1.6 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Mad3_BUB1_II PF08171.11 KSA01982.1 - 3.6e-21 75.1 0.0 2.2e-20 72.6 0.1 2.4 2 0 0 2 2 2 1 Mad3/BUB1 homology region 2 Pkinase PF00069.25 KSA01982.1 - 4.8e-18 65.5 0.3 9e-18 64.6 0.3 1.4 1 0 0 1 1 1 1 Protein kinase domain Mad3_BUB1_I_2 PF17014.5 KSA01982.1 - 4.9e-08 33.2 1.2 2e-07 31.2 0.3 2.3 2 0 0 2 2 2 1 Putative Mad3/BUB1 like region 1 protein Pkinase_Tyr PF07714.17 KSA01982.1 - 5e-07 29.3 0.0 1.1e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KSA01982.1 - 0.021 14.2 0.1 0.039 13.3 0.1 1.3 1 0 0 1 1 1 0 Kinase-like Pyr_redox_2 PF07992.14 KSA01983.1 - 1.3e-23 83.6 0.0 2.4e-23 82.8 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KSA01983.1 - 5.9e-07 30.0 0.5 1.2e-05 25.8 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KSA01983.1 - 3.6e-05 23.8 0.4 0.0016 18.4 0.0 3.0 3 1 0 3 3 3 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 KSA01983.1 - 0.0058 15.8 0.0 0.014 14.5 0.0 1.6 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Bgal_small_N PF02929.17 KSA01983.1 - 0.077 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Beta galactosidase small chain FAD_binding_3 PF01494.19 KSA01983.1 - 0.14 11.3 0.4 7.9 5.6 0.7 2.8 2 1 0 2 2 2 0 FAD binding domain PhoLip_ATPase_C PF16212.5 KSA01984.1 - 2.1e-66 224.2 22.1 2.1e-66 224.2 22.1 2.3 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KSA01984.1 - 1.2e-23 82.5 5.2 3e-23 81.3 0.3 2.9 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KSA01984.1 - 2.3e-14 54.2 0.5 2.2e-07 31.4 0.0 3.5 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KSA01984.1 - 2.3e-12 46.8 0.0 7.2e-12 45.2 0.0 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase PF13246.6 KSA01984.1 - 6.3e-12 45.4 0.0 4e-11 42.8 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KSA01984.1 - 0.0024 17.7 0.0 0.0024 17.7 0.0 3.0 4 0 0 4 4 4 1 haloacid dehalogenase-like hydrolase DUF4181 PF13789.6 KSA01984.1 - 1.8 8.8 5.7 19 5.6 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4181) DAO PF01266.24 KSA01985.1 - 1e-24 87.8 0.0 1.2e-24 87.5 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KSA01985.1 - 0.038 13.2 0.0 0.1 11.8 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KSA01985.1 - 0.11 11.7 0.0 0.3 10.3 0.1 1.7 2 0 0 2 2 2 0 Thi4 family Trp_halogenase PF04820.14 KSA01985.1 - 0.13 11.1 0.0 0.24 10.2 0.0 1.4 1 0 0 1 1 1 0 Tryptophan halogenase VTC PF09359.10 KSA01986.1 - 1.1e-101 339.9 0.3 1.1e-101 339.9 0.3 1.9 2 0 0 2 2 2 1 VTC domain DUF202 PF02656.15 KSA01986.1 - 1.4e-10 41.5 2.8 1.4e-10 41.5 2.8 1.9 3 0 0 3 3 3 1 Domain of unknown function (DUF202) SPX PF03105.19 KSA01986.1 - 1.1e-09 38.7 26.9 8.1e-07 29.3 1.9 3.7 2 1 2 4 4 4 3 SPX domain Rrn6 PF10214.9 KSA01986.1 - 0.0023 16.6 0.8 0.0034 16.0 0.8 1.1 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor MazG PF03819.17 KSA01986.1 - 0.0055 16.9 0.1 0.012 15.8 0.1 1.5 1 0 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain LXG PF04740.12 KSA01986.1 - 0.018 14.8 3.3 0.034 13.8 0.4 2.4 1 1 1 2 2 2 0 LXG domain of WXG superfamily HIP1_clath_bdg PF16515.5 KSA01986.1 - 0.7 10.5 5.9 0.13 12.9 0.7 2.2 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 TMF_DNA_bd PF12329.8 KSA01986.1 - 2.1 8.4 9.4 2 8.5 0.9 2.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding YscO-like PF16789.5 KSA01986.1 - 8.3 6.4 11.3 0.64 10.0 4.0 2.3 2 0 0 2 2 2 0 YscO-like protein DAO PF01266.24 KSA01987.1 - 1e-54 186.5 0.0 1.1e-54 186.3 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KSA01987.1 - 0.0022 18.2 0.2 0.0048 17.1 0.2 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KSA01987.1 - 0.0061 15.8 0.2 0.044 13.0 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KSA01987.1 - 0.0095 16.5 0.4 0.06 13.9 0.3 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.15 KSA01987.1 - 0.019 13.5 0.0 2.1 6.8 0.2 2.2 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) TrkA_N PF02254.18 KSA01987.1 - 0.029 14.6 0.1 0.067 13.5 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox_3 PF13738.6 KSA01987.1 - 0.12 11.6 0.3 0.21 10.8 0.3 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KSA01987.1 - 0.14 11.8 0.1 0.26 10.9 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pkinase PF00069.25 KSA01988.1 - 1.4e-68 231.1 0.0 1.6e-68 230.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KSA01988.1 - 6.3e-30 104.3 0.0 8.4e-30 103.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KSA01988.1 - 0.00016 21.1 0.0 0.00021 20.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KSA01988.1 - 0.026 14.5 0.2 0.049 13.6 0.2 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family SH3_1 PF00018.28 KSA01989.1 - 2.5e-07 30.2 0.8 6.5e-07 28.9 0.8 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KSA01989.1 - 0.00019 21.1 0.3 0.00042 20.0 0.3 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KSA01989.1 - 0.00023 21.0 0.4 0.00056 19.7 0.4 1.7 1 0 0 1 1 1 1 Variant SH3 domain Cpn60_TCP1 PF00118.24 KSA01990.1 - 3.6e-169 563.5 1.8 4.1e-169 563.3 1.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family NusA_N PF08529.11 KSA01990.1 - 0.027 14.8 1.8 0.079 13.3 1.5 2.0 2 0 0 2 2 2 0 NusA N-terminal domain DUF2344 PF10105.9 KSA01990.1 - 0.076 12.9 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) RINT1_TIP1 PF04437.13 KSA01991.1 - 6.1e-111 371.8 29.1 6.1e-111 371.8 29.1 1.5 2 0 0 2 2 2 1 RINT-1 / TIP-1 family Osmo_CC PF08946.10 KSA01991.1 - 3.3 8.0 5.7 6.4 7.1 0.2 3.5 3 0 0 3 3 3 0 Osmosensory transporter coiled coil NPV_P10 PF05531.12 KSA01991.1 - 3.7 8.1 5.6 5 7.7 0.0 4.0 5 0 0 5 5 5 0 Nucleopolyhedrovirus P10 protein Pkinase PF00069.25 KSA01992.1 - 2.3e-65 220.6 0.0 2.8e-65 220.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KSA01992.1 - 3.8e-31 108.3 0.0 4.9e-31 108.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 KSA01992.1 - 6e-16 58.6 0.7 1.3e-15 57.5 0.7 1.6 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KSA01992.1 - 2.2e-05 24.7 0.1 6.3e-05 23.2 0.0 1.7 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain Pkinase_fungal PF17667.1 KSA01992.1 - 6.7e-05 21.8 0.0 0.00011 21.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase FHA_2 PF17913.1 KSA01992.1 - 0.00015 21.9 0.0 0.00032 20.9 0.0 1.5 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.6 KSA01992.1 - 0.00096 18.5 0.2 0.93 8.8 0.2 3.0 2 1 1 3 3 3 2 Kinase-like Kdo PF06293.14 KSA01992.1 - 0.0049 16.2 0.1 0.0078 15.6 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 KSA01992.1 - 0.033 13.7 0.1 0.058 12.9 0.1 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.23 KSA01992.1 - 0.13 12.2 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 KSA01992.1 - 0.14 11.8 0.1 0.62 9.6 0.1 1.8 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Sel1 PF08238.12 KSA01993.1 - 0.00038 21.0 0.4 19 6.1 0.0 4.8 5 0 0 5 5 5 3 Sel1 repeat MOR2-PAG1_C PF14225.6 KSA01994.1 - 1.8e-91 306.5 0.1 1.8e-91 306.5 0.1 1.8 2 0 0 2 2 2 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.6 KSA01994.1 - 3.5e-11 41.5 1.1 7.2e-11 40.5 1.1 1.4 1 1 0 1 1 1 1 Cell morphogenesis central region Cnd1 PF12717.7 KSA01994.1 - 0.023 14.8 0.9 0.17 11.9 0.1 2.5 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 DFRP_C PF16543.5 KSA01995.1 - 1.2e-23 83.4 10.5 1.2e-23 83.4 10.5 4.0 4 0 0 4 4 4 1 DRG Family Regulatory Proteins, Tma46 Torus PF16131.5 KSA01995.1 - 8.1e-06 26.5 17.5 8.6e-05 23.2 5.4 4.1 2 1 1 3 3 3 2 Torus domain zf-CCCH PF00642.24 KSA01995.1 - 1.1e-05 25.2 0.8 1.1e-05 25.2 0.8 2.6 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KSA01995.1 - 1.3e-05 24.9 9.7 4.2e-05 23.2 1.4 3.3 3 0 0 3 3 3 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KSA01995.1 - 2.1e-05 24.4 5.6 2.1e-05 24.4 5.6 3.2 3 0 0 3 3 3 1 Zinc finger domain zf-CCCH_3 PF15663.5 KSA01995.1 - 0.12 12.6 6.0 0.54 10.5 1.2 2.7 1 1 1 2 2 2 0 Zinc-finger containing family zf-CCCH_2 PF14608.6 KSA01995.1 - 0.85 10.2 13.0 0.21 12.1 3.7 2.7 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger DUF2183 PF09949.9 KSA01996.1 - 5.2e-33 113.3 0.0 1.6e-32 111.8 0.0 1.9 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) Mis14 PF08641.12 KSA01996.1 - 0.1 12.9 0.3 0.1 12.9 0.3 2.4 3 0 0 3 3 3 0 Kinetochore protein Mis14 like SH3_1 PF00018.28 KSA01997.1 - 2.7e-23 81.3 1.8 5.4e-11 41.9 0.0 3.2 3 0 0 3 3 3 2 SH3 domain SH3_9 PF14604.6 KSA01997.1 - 1.2e-22 79.4 1.0 5.4e-13 48.6 0.1 2.5 2 0 0 2 2 2 2 Variant SH3 domain FCH PF00611.23 KSA01997.1 - 2.3e-20 72.7 2.9 4e-20 71.9 0.1 2.6 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_2 PF07653.17 KSA01997.1 - 1.5e-12 47.0 0.0 7.9e-07 28.7 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_10 PF17902.1 KSA01997.1 - 1.2e-05 25.2 0.0 0.046 13.8 0.0 3.0 2 0 0 2 2 2 2 SH3 domain SH3_3 PF08239.11 KSA01997.1 - 0.0053 17.0 0.0 0.019 15.3 0.0 2.0 1 0 0 1 1 1 1 Bacterial SH3 domain ApoO PF09769.9 KSA01997.1 - 0.56 10.2 1.8 1.4 8.9 1.3 1.9 2 0 0 2 2 2 0 Apolipoprotein O Spectrin_like PF18373.1 KSA01997.1 - 2.5 8.3 6.2 0.69 10.0 0.3 2.7 3 0 0 3 3 3 0 Spectrin like domain Ribosomal_S7e PF01251.18 KSA01998.1 - 6.4e-80 267.3 1.2 7.1e-80 267.1 1.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e SPOR PF05036.13 KSA01998.1 - 0.1 13.0 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 Sporulation related domain Rib_5-P_isom_A PF06026.14 KSA01999.1 - 5.9e-61 205.1 0.1 7.3e-61 204.8 0.1 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.22 KSA01999.1 - 0.0073 16.3 0.0 1.9 8.4 0.0 2.2 1 1 1 2 2 2 2 DeoR C terminal sensor domain Sugar-bind PF04198.13 KSA01999.1 - 0.095 11.8 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Putative sugar-binding domain Arf PF00025.21 KSA02000.1 - 1.3e-67 226.6 0.1 1.6e-67 226.3 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KSA02000.1 - 2.6e-15 56.7 0.0 3.4e-15 56.3 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 KSA02000.1 - 5.3e-14 52.1 0.8 5.2e-09 35.7 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 KSA02000.1 - 3.7e-12 46.2 0.0 4e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 KSA02000.1 - 1.2e-11 44.4 0.0 1.5e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KSA02000.1 - 1e-08 34.8 0.0 1.4e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KSA02000.1 - 3.1e-05 24.0 0.0 5.3e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 KSA02000.1 - 0.0049 16.2 0.1 0.0073 15.6 0.1 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase MobB PF03205.14 KSA02000.1 - 0.024 14.5 0.0 0.037 13.9 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B FeoB_N PF02421.18 KSA02000.1 - 0.15 11.6 0.2 0.87 9.1 0.2 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B OB_NTP_bind PF07717.16 KSA02001.1 - 2.1e-23 82.5 0.0 6.7e-23 80.9 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 KSA02001.1 - 1.5e-19 70.3 0.1 3.9e-19 68.9 0.1 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KSA02001.1 - 5.4e-11 42.8 0.0 1.5e-10 41.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KSA02001.1 - 1.8e-08 34.3 0.1 3.7e-08 33.4 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KSA02001.1 - 2.2e-05 24.7 0.1 0.00011 22.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 KSA02001.1 - 7.5e-05 22.4 0.1 0.00021 21.0 0.1 1.6 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_30 PF13604.6 KSA02001.1 - 0.0014 18.4 0.0 0.0022 17.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.14 KSA02001.1 - 0.0031 17.5 0.1 0.007 16.3 0.1 1.6 1 0 0 1 1 1 1 Flavivirus DEAD domain AAA_19 PF13245.6 KSA02001.1 - 0.0073 16.7 0.1 0.015 15.6 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 KSA02001.1 - 0.034 14.7 0.0 0.13 12.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 KSA02001.1 - 0.048 12.9 0.0 0.081 12.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RsgA_GTPase PF03193.16 KSA02001.1 - 0.15 12.0 0.0 1.6 8.6 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase ABC1 PF03109.16 KSA02002.1 - 1.3e-31 109.2 0.0 2.6e-31 108.3 0.0 1.5 1 0 0 1 1 1 1 ABC1 family FUSC_2 PF13515.6 KSA02003.1 - 5.8e-34 117.0 6.8 5.8e-34 117.0 6.8 2.7 2 1 0 2 2 2 1 Fusaric acid resistance protein-like ArAE_2 PF10334.9 KSA02003.1 - 4.4e-09 36.5 1.8 5.7e-08 32.9 0.1 2.3 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 FUSC PF04632.12 KSA02003.1 - 0.00012 20.8 4.4 0.00064 18.4 2.2 2.4 2 1 1 3 3 3 1 Fusaric acid resistance protein family DUF3951 PF13131.6 KSA02003.1 - 0.034 14.4 0.0 0.15 12.3 0.0 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3951) DUF5365 PF17326.2 KSA02003.1 - 0.053 13.9 0.1 0.25 11.8 0.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5365) zf-CCCH_2 PF14608.6 KSA02004.1 - 3.3e-23 81.3 68.5 1.9e-07 31.3 4.6 7.3 7 0 0 7 7 7 5 RNA-binding, Nab2-type zinc finger TFIIA PF03153.13 KSA02004.1 - 0.0084 16.2 10.0 0.013 15.5 10.0 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Nab2 PF11517.8 KSA02004.1 - 0.045 14.0 0.0 0.088 13.1 0.0 1.4 1 0 0 1 1 1 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) zf-CCCH_4 PF18044.1 KSA02004.1 - 0.27 11.1 32.6 2.1 8.3 0.8 8.2 9 0 0 9 9 9 0 CCCH-type zinc finger PAT1 PF09770.9 KSA02004.1 - 3.6 5.8 15.7 5.2 5.2 15.7 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ribosomal_S5 PF00333.20 KSA02005.1 - 2e-26 91.8 3.2 3.2e-26 91.1 2.4 1.8 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 KSA02005.1 - 8.3e-24 82.8 0.1 1.4e-23 82.1 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain CoA_binding_3 PF13727.6 KSA02005.1 - 0.12 12.4 0.1 0.34 10.9 0.0 1.7 1 1 1 2 2 2 0 CoA-binding domain DSS1_SEM1 PF05160.13 KSA02006.1 - 0.086 12.9 1.9 0.15 12.1 1.9 1.4 1 0 0 1 1 1 0 DSS1/SEM1 family YtxH PF12732.7 KSA02006.1 - 2.6 8.6 7.4 0.21 12.2 1.4 2.3 2 1 0 2 2 2 0 YtxH-like protein DUF4407 PF14362.6 KSA02008.1 - 3.6 6.8 10.2 12 5.1 10.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) EXOSC1 PF10447.9 KSA02010.1 - 6.3e-46 155.5 0.0 1.3e-45 154.4 0.0 1.6 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 KSA02010.1 - 0.5 10.2 2.3 2.3 8.1 2.3 2.2 1 1 0 1 1 1 0 Exosome complex exonuclease RRP4 N-terminal region CRAL_TRIO PF00650.20 KSA02011.1 - 3.3e-39 134.2 0.0 5e-39 133.6 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KSA02011.1 - 1.1e-18 67.1 3.4 2.7e-18 65.9 3.4 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Lig_C PF18330.1 KSA02011.1 - 0.077 13.0 0.1 0.21 11.6 0.1 1.8 1 0 0 1 1 1 0 Ligase Pab1020 C-terminal region Elongin_A PF06881.11 KSA02012.1 - 7.6e-25 87.5 0.0 1.3e-24 86.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A RNase_P_p30 PF01876.16 KSA02013.1 - 1.9e-83 279.2 0.3 2.8e-83 278.6 0.3 1.2 1 0 0 1 1 1 1 RNase P subunit p30 YxiJ PF14176.6 KSA02013.1 - 0.11 13.0 0.2 0.36 11.3 0.1 1.9 2 0 0 2 2 2 0 YxiJ-like protein zf-AN1 PF01428.16 KSA02014.1 - 2.7e-09 37.0 14.0 4.4e-09 36.3 14.0 1.4 1 0 0 1 1 1 1 AN1-like Zinc finger Pkinase PF00069.25 KSA02015.1 - 2.8e-25 89.2 0.0 4.5e-25 88.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KSA02015.1 - 3.3e-12 46.2 0.0 4.6e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KSA02015.1 - 6.1e-06 25.3 0.1 6.1e-06 25.3 0.1 1.9 2 0 0 2 2 2 1 Fungal protein kinase PIP49_C PF12260.8 KSA02015.1 - 0.006 16.2 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 Methyltransf_23 PF13489.6 KSA02016.1 - 3.4e-16 59.5 0.0 1.9e-15 57.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KSA02016.1 - 2e-14 53.6 0.0 2.8e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KSA02016.1 - 3.3e-14 53.3 0.0 7.4e-14 52.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KSA02016.1 - 7e-14 52.4 0.0 1.3e-13 51.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KSA02016.1 - 3.4e-13 50.1 0.0 6.9e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KSA02016.1 - 2e-09 37.2 0.0 3.6e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 KSA02016.1 - 4.8e-05 23.5 0.3 0.00011 22.4 0.0 1.8 2 1 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_32 PF13679.6 KSA02016.1 - 7.2e-05 22.8 0.0 0.00018 21.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KSA02016.1 - 0.00031 20.2 0.0 0.00045 19.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KSA02016.1 - 0.00041 20.0 0.0 0.00088 18.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain CheR PF01739.18 KSA02016.1 - 0.0045 16.5 0.0 0.13 11.8 0.0 2.2 1 1 0 2 2 2 1 CheR methyltransferase, SAM binding domain TrkA_N PF02254.18 KSA02016.1 - 0.0049 17.1 0.0 0.086 13.1 0.0 2.4 1 1 1 2 2 2 1 TrkA-N domain PCMT PF01135.19 KSA02016.1 - 0.0057 16.4 0.0 0.01 15.6 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CmcI PF04989.12 KSA02016.1 - 0.0086 15.8 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 Cephalosporin hydroxylase CMAS PF02353.20 KSA02016.1 - 0.078 12.3 0.0 0.28 10.5 0.0 1.8 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase DUF3420 PF11900.8 KSA02016.1 - 0.079 13.1 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3420) UQ_con PF00179.26 KSA02017.1 - 6e-21 74.6 0.1 8.4e-21 74.1 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme NRIP1_repr_1 PF15687.5 KSA02017.1 - 0.027 14.1 0.2 0.037 13.7 0.2 1.2 1 0 0 1 1 1 0 Nuclear receptor-interacting protein 1 repression 1 RWD PF05773.22 KSA02017.1 - 0.11 12.8 0.8 0.26 11.6 0.8 1.5 1 1 0 1 1 1 0 RWD domain Sel1 PF08238.12 KSA02018.1 - 1.1e-47 159.4 22.8 3.4e-08 33.9 0.1 8.1 8 0 0 8 8 8 7 Sel1 repeat Epimerase PF01370.21 KSA02019.1 - 1.1e-11 44.7 0.0 1.5e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KSA02019.1 - 4.8e-10 38.9 0.0 6.1e-10 38.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KSA02019.1 - 5.7e-09 35.5 0.0 7e-09 35.2 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein KR PF08659.10 KSA02019.1 - 0.12 12.3 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 KR domain Rick_17kDa_Anti PF05433.15 KSA02020.1 - 2.3e-06 27.4 14.8 2.3e-06 27.4 14.8 6.6 2 1 4 6 6 6 1 Glycine zipper 2TM domain Kinesin PF00225.23 KSA02021.1 - 4e-117 390.9 0.1 6.5e-117 390.2 0.1 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KSA02021.1 - 6.4e-25 87.8 0.0 1.8e-24 86.4 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding Aa_trans PF01490.18 KSA02022.1 - 4e-97 325.5 33.9 4.7e-97 325.3 33.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PetN PF03742.14 KSA02022.1 - 1.8 8.5 9.9 2.6 8.0 0.1 3.9 3 0 0 3 3 3 0 PetN Trp_Tyr_perm PF03222.13 KSA02022.1 - 2.2 7.2 33.0 0.0074 15.4 19.4 2.6 2 1 1 3 3 3 0 Tryptophan/tyrosine permease family TRAM_LAG1_CLN8 PF03798.16 KSA02023.1 - 3.1e-44 151.1 30.1 3.1e-44 151.1 30.1 1.6 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 KSA02023.1 - 1.2e-19 69.6 4.8 1.2e-18 66.5 0.7 2.5 2 0 0 2 2 2 2 TRAM1-like protein Cyclin_N PF00134.23 KSA02024.1 - 1.1e-12 47.8 0.7 2.1e-12 46.9 0.7 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Pro_isomerase PF00160.21 KSA02025.1 - 8.6e-29 100.8 0.0 9.5e-29 100.7 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DFP PF04127.15 KSA02026.1 - 1.1e-19 71.0 0.0 4e-11 43.1 0.0 2.1 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein BclA_C PF18573.1 KSA02026.1 - 0.069 13.1 0.1 0.14 12.1 0.1 1.5 1 0 0 1 1 1 0 BclA C-terminal domain Bac_surface_Ag PF01103.23 KSA02027.1 - 2.9e-42 145.3 7.8 3.9e-42 144.9 7.8 1.2 1 0 0 1 1 1 1 Surface antigen DUF2780 PF11075.8 KSA02027.1 - 0.021 15.0 0.2 0.061 13.5 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function VcgC/VcgE (DUF2780) zf-RVT PF13966.6 KSA02027.1 - 0.12 13.2 0.6 0.26 12.0 0.6 1.6 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase Chalcone_2 PF16035.5 KSA02027.1 - 0.36 10.6 2.2 0.58 9.9 2.2 1.2 1 0 0 1 1 1 0 Chalcone isomerase like zf-C2H2 PF00096.26 KSA02028.1 - 8.9e-14 51.1 15.7 1.5e-06 28.3 3.8 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KSA02028.1 - 2e-11 43.8 12.8 1.4e-05 25.3 0.2 4.1 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KSA02028.1 - 4.7e-09 36.3 10.8 0.0013 19.4 2.4 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KSA02028.1 - 1.3e-06 28.6 3.7 0.0086 16.3 0.4 3.7 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KSA02028.1 - 2.2e-06 27.5 9.1 0.00068 19.6 0.7 4.2 4 0 0 4 4 4 2 C2H2-type zinc finger zf-met PF12874.7 KSA02028.1 - 1.4e-05 25.3 8.1 0.00063 20.1 0.5 4.3 4 0 0 4 4 4 1 Zinc-finger of C2H2 type Zn_ribbon_recom PF13408.6 KSA02028.1 - 0.038 14.5 0.7 0.038 14.5 0.7 2.0 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain zf-C2H2_11 PF16622.5 KSA02028.1 - 0.11 12.3 5.6 0.93 9.3 0.1 3.3 3 0 0 3 3 3 0 zinc-finger C2H2-type Zn-ribbon_8 PF09723.10 KSA02028.1 - 0.13 12.4 0.9 0.32 11.2 0.9 1.7 1 0 0 1 1 1 0 Zinc ribbon domain zf-C2HE PF16278.5 KSA02028.1 - 0.14 12.7 6.9 1.2 9.6 1.1 3.6 3 1 1 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2HC_2 PF13913.6 KSA02028.1 - 0.21 11.5 4.1 0.22 11.5 0.2 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type FYVE PF01363.21 KSA02028.1 - 0.22 11.7 5.1 0.48 10.6 5.1 1.6 1 0 0 1 1 1 0 FYVE zinc finger zf-BED PF02892.15 KSA02028.1 - 1.2 9.2 4.9 23 5.1 0.8 2.9 1 1 1 2 2 2 0 BED zinc finger Met_10 PF02475.16 KSA02029.1 - 4.2e-09 36.4 0.0 7.9e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein DUF2895 PF11444.8 KSA02029.1 - 0.13 11.6 0.1 3.4 7.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2895) MTS PF05175.14 KSA02029.1 - 0.16 11.5 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain RRM_1 PF00076.22 KSA02030.1 - 7.5e-55 182.7 0.0 2.2e-19 69.0 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KSA02030.1 - 6.8e-11 41.9 0.0 1.8e-05 24.5 0.0 3.3 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_5 PF13893.6 KSA02030.1 - 5.4e-10 38.9 0.0 2e-05 24.2 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cas_Cas2CT1978 PF09707.10 KSA02030.1 - 0.00011 22.2 0.0 0.16 12.1 0.0 2.5 2 0 0 2 2 2 2 CRISPR-associated protein (Cas_Cas2CT1978) Nup35_RRM_2 PF14605.6 KSA02030.1 - 0.00025 21.0 0.0 0.55 10.3 0.0 2.8 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 KSA02030.1 - 0.0033 17.5 0.0 0.55 10.4 0.0 3.2 2 1 0 2 2 2 1 RNA recognition motif DUF3421 PF11901.8 KSA02030.1 - 0.14 12.2 0.1 5.1 7.1 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3421) BRF1 PF07741.13 KSA02030.1 - 2.9 8.3 10.5 1.5 9.2 4.7 2.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain UCH PF00443.29 KSA02031.1 - 2e-43 148.8 0.0 4.2e-43 147.7 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KSA02031.1 - 2.2e-06 27.5 0.3 0.00032 20.4 0.1 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUF2431 PF10354.9 KSA02032.1 - 7.6e-58 195.5 0.2 1.2e-57 194.9 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) CLTH PF10607.9 KSA02033.1 - 2.2e-36 125.0 4.1 2.2e-36 125.0 4.1 2.4 2 1 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain Fis1_TPR_N PF14852.6 KSA02033.1 - 0.021 14.5 0.2 0.041 13.6 0.2 1.5 1 0 0 1 1 1 0 Fis1 N-terminal tetratricopeptide repeat COG2 PF06148.11 KSA02033.1 - 0.085 12.9 1.1 4.5 7.4 0.6 3.0 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 IZUMO PF15005.6 KSA02033.1 - 1.8 9.1 7.5 0.69 10.4 2.3 2.7 3 1 0 3 3 3 0 Izumo sperm-egg fusion, Ig domain-associated Rad50_zn_hook PF04423.14 KSA02033.1 - 6.9 6.6 6.4 8.4 6.3 0.4 3.6 3 0 0 3 3 3 0 Rad50 zinc hook motif GDA1_CD39 PF01150.17 KSA02034.1 - 1.3e-73 248.1 0.5 4.7e-43 147.4 0.0 3.2 2 1 0 3 3 3 3 GDA1/CD39 (nucleoside phosphatase) family RPOL_N PF14700.6 KSA02034.1 - 0.022 14.2 1.6 0.037 13.4 1.6 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal CDC45 PF02724.14 KSA02034.1 - 0.26 9.5 10.9 0.42 8.9 10.9 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF5517 PF17639.2 KSA02034.1 - 0.48 10.7 0.0 0.48 10.7 0.0 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5517) PLDc_N PF13396.6 KSA02034.1 - 1.3 9.0 4.7 2.4 8.2 4.7 1.4 1 0 0 1 1 1 0 Phospholipase_D-nuclease N-terminal Nop14 PF04147.12 KSA02034.1 - 2.2 6.4 18.3 3.5 5.7 18.3 1.2 1 0 0 1 1 1 0 Nop14-like family TFIIF_alpha PF05793.12 KSA02034.1 - 4.3 5.8 26.4 7.2 5.1 26.4 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Roughex PF06020.11 KSA02034.1 - 4.4 6.3 6.8 7.1 5.6 6.8 1.2 1 0 0 1 1 1 0 Drosophila roughex protein PseudoU_synth_2 PF00849.22 KSA02036.1 - 3.9e-33 114.8 0.1 5.8e-33 114.2 0.1 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase Presenilin PF01080.17 KSA02037.1 - 0.4 9.4 5.6 0.56 8.9 5.6 1.1 1 0 0 1 1 1 0 Presenilin Thiolase_N PF00108.23 KSA02039.1 - 1.9e-83 279.8 0.7 2.8e-83 279.3 0.7 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KSA02039.1 - 1.3e-44 150.8 0.2 2.2e-44 150.0 0.2 1.4 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KSA02039.1 - 0.00047 19.8 1.0 0.0013 18.4 0.4 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KSA02039.1 - 0.051 13.4 2.0 2 8.3 0.1 3.0 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III NDT80_PhoG PF05224.12 KSA02040.1 - 7.2e-47 160.0 3.6 7.2e-47 160.0 3.6 2.8 3 0 0 3 3 3 1 NDT80 / PhoG like DNA-binding family CttA_N PF18244.1 KSA02040.1 - 0.066 13.6 4.6 0.14 12.6 1.7 2.8 2 0 0 2 2 2 0 Cellulose-binding protein CttA N-terminal domain Pkinase PF00069.25 KSA02041.1 - 8.1e-62 209.0 0.2 1.4e-61 208.2 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KSA02041.1 - 2.1e-29 102.6 0.0 3.8e-29 101.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KSA02041.1 - 0.0073 15.3 3.5 0.031 13.2 0.1 2.6 2 1 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 KSA02041.1 - 0.15 12.0 0.1 0.27 11.1 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family GET2 PF08690.10 KSA02041.1 - 2.5 7.7 12.0 3.6 7.2 12.0 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 DUF2756 PF10956.8 KSA02041.1 - 2.8 8.5 19.7 4.9 7.7 19.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2756) WD40 PF00400.32 KSA02042.1 - 1.4e-05 25.7 1.5 0.094 13.6 0.0 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat EPL1 PF10513.9 KSA02043.1 - 3.8e-29 102.1 5.4 3.8e-29 102.1 5.4 5.0 4 2 0 4 4 4 1 Enhancer of polycomb-like FTHFS PF01268.19 KSA02044.1 - 4.6e-244 810.7 0.3 5.8e-244 810.4 0.3 1.1 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 KSA02044.1 - 1.6e-65 219.3 1.4 1.6e-65 219.3 1.4 2.0 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 KSA02044.1 - 2.7e-34 117.9 0.3 1.3e-33 115.7 0.4 2.1 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain AdoHcyase_NAD PF00670.21 KSA02044.1 - 0.11 12.5 1.2 5.4 7.1 1.1 2.9 2 1 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain FH2 PF02181.23 KSA02045.1 - 6.1e-79 265.8 16.1 6.1e-79 265.8 16.1 3.5 3 0 0 3 3 3 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 KSA02045.1 - 1.8e-15 57.1 2.2 1.8e-15 57.1 2.2 5.3 5 2 2 7 7 7 1 Diaphanous FH3 Domain Drf_GBD PF06371.13 KSA02045.1 - 8.4e-14 51.6 11.1 8.4e-14 51.6 11.1 6.6 5 1 0 5 5 5 2 Diaphanous GTPase-binding Domain PIF1 PF05970.14 KSA02046.1 - 2e-52 178.6 4.2 2e-49 168.7 3.2 3.2 2 1 0 2 2 2 1 PIF1-like helicase AAA_30 PF13604.6 KSA02046.1 - 8.1e-23 81.1 0.0 1.4e-22 80.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KSA02046.1 - 9.3e-08 32.5 0.0 3.5e-07 30.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain Herpes_Helicase PF02689.14 KSA02046.1 - 6.2e-06 24.5 0.1 6e-05 21.2 0.0 2.1 2 0 0 2 2 2 1 Helicase AAA_22 PF13401.6 KSA02046.1 - 0.00039 20.7 0.0 0.0014 18.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KSA02046.1 - 0.00041 20.2 0.7 0.39 10.4 0.0 3.5 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 KSA02046.1 - 0.0011 18.3 0.0 0.0028 17.0 0.0 1.6 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 KSA02046.1 - 0.005 16.4 0.1 0.01 15.4 0.1 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region UvrD_C_2 PF13538.6 KSA02046.1 - 0.01 15.6 0.3 0.085 12.7 0.3 2.4 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain SH3_13 PF18335.1 KSA02046.1 - 0.011 15.6 0.0 0.031 14.1 0.0 1.7 1 0 0 1 1 1 0 ATP-dependent RecD-like DNA helicase SH3 domain AAA PF00004.29 KSA02046.1 - 0.032 14.6 0.1 0.086 13.3 0.1 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.18 KSA02046.1 - 0.035 13.5 0.1 0.067 12.5 0.1 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_16 PF13191.6 KSA02046.1 - 0.086 13.2 0.1 0.24 11.8 0.1 1.7 1 0 0 1 1 1 0 AAA ATPase domain Helicase_RecD PF05127.14 KSA02046.1 - 0.098 12.5 1.4 0.42 10.5 0.2 2.6 2 2 0 2 2 2 0 Helicase AAA_5 PF07728.14 KSA02046.1 - 0.13 12.3 0.3 1.5 8.8 0.1 2.8 3 1 0 3 3 3 0 AAA domain (dynein-related subfamily) DUF1694 PF07997.11 KSA02047.1 - 0.0064 16.6 1.4 0.01 15.9 0.1 2.0 2 1 0 2 2 2 1 Protein of unknown function (DUF1694) Arc_PepC_II PF06847.11 KSA02047.1 - 0.14 12.7 0.2 0.34 11.5 0.2 1.8 1 1 0 1 1 1 0 Archaeal Peptidase A24 C-terminus Type II zf-RING_2 PF13639.6 KSA02048.1 - 1e-06 28.9 8.5 2.7e-06 27.6 8.5 1.8 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 KSA02048.1 - 2.7e-06 27.5 6.0 7.2e-06 26.1 5.2 2.2 2 0 0 2 2 1 1 FANCL C-terminal domain zf-ANAPC11 PF12861.7 KSA02048.1 - 0.00031 20.7 2.4 0.00085 19.3 2.4 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KSA02048.1 - 0.0013 19.0 7.8 0.0038 17.5 7.8 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain RINGv PF12906.7 KSA02048.1 - 0.0085 16.2 6.3 0.019 15.1 6.3 1.7 1 0 0 1 1 1 1 RING-variant domain zf-C3HC4 PF00097.25 KSA02048.1 - 0.02 14.8 9.2 0.046 13.6 9.2 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 KSA02048.1 - 0.05 13.9 6.8 0.098 13.0 6.8 1.5 1 0 0 1 1 1 0 RING-like domain Zn_ribbon_17 PF17120.5 KSA02048.1 - 0.067 12.8 5.7 0.14 11.8 5.7 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 KSA02048.1 - 0.32 10.8 5.6 4.2 7.2 1.0 2.6 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.6 KSA02048.1 - 0.43 10.5 9.1 1 9.3 9.1 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KSA02048.1 - 0.73 9.7 4.2 17 5.4 4.2 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF2256 PF10013.9 KSA02048.1 - 2.2 8.5 3.6 2.2 8.5 0.5 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) C1_1 PF00130.22 KSA02048.1 - 3.4 7.6 5.7 1.6 8.7 3.2 1.7 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_4 PF14447.6 KSA02048.1 - 3.4 7.6 6.8 1.9 8.4 0.4 2.5 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 PHD PF00628.29 KSA02048.1 - 8.3 6.4 6.3 15 5.5 6.3 1.5 1 0 0 1 1 1 0 PHD-finger PTPA PF03095.15 KSA02049.1 - 2.4e-102 342.5 0.0 2.9e-102 342.2 0.0 1.1 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein XPG_I PF00867.18 KSA02050.1 - 1e-24 86.7 0.0 3.1e-24 85.1 0.0 1.9 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.7 KSA02050.1 - 0.0004 19.9 0.2 0.00098 18.7 0.0 1.7 2 0 0 2 2 2 1 XPG domain containing XPG_N PF00752.17 KSA02050.1 - 0.00055 20.4 0.0 0.0017 18.8 0.0 1.9 1 0 0 1 1 1 1 XPG N-terminal domain Glyco_hydro_3 PF00933.21 KSA02051.1 - 1.3e-53 182.5 0.0 2.1e-53 181.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Acetyltransf_1 PF00583.25 KSA02051.1 - 0.034 14.4 0.0 0.11 12.8 0.0 2.0 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family CRCB PF02537.15 KSA02052.1 - 1.4e-32 111.9 14.4 1.4e-19 70.1 5.3 2.6 2 0 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) Phage_holin_3_1 PF05106.12 KSA02052.1 - 0.56 10.7 3.1 9 6.8 0.0 3.5 3 1 0 3 3 3 0 Phage holin family (Lysis protein S) Enolase_C PF00113.22 KSA02053.1 - 2e-137 457.4 0.0 3e-137 456.8 0.0 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 KSA02053.1 - 4.5e-58 195.1 0.5 8.9e-58 194.1 0.5 1.5 1 0 0 1 1 1 1 Enolase, N-terminal domain MAAL_C PF07476.11 KSA02053.1 - 0.0012 18.0 0.1 0.0027 16.9 0.0 1.6 2 0 0 2 2 2 1 Methylaspartate ammonia-lyase C-terminus MR_MLE_C PF13378.6 KSA02053.1 - 0.043 13.4 0.0 0.069 12.7 0.0 1.4 1 0 0 1 1 1 0 Enolase C-terminal domain-like Ion_trans_2 PF07885.16 KSA02054.1 - 2.3e-27 94.8 40.0 1.7e-17 63.1 11.0 3.7 3 1 0 3 3 3 2 Ion channel Ion_trans PF00520.31 KSA02054.1 - 0.084 12.1 37.4 0.42 9.8 6.1 3.4 2 1 0 2 2 2 0 Ion transport protein Lig_chan PF00060.26 KSA02054.1 - 0.96 9.3 14.3 1.6 8.6 2.1 3.5 3 1 0 3 3 3 0 Ligand-gated ion channel HPP PF04982.13 KSA02055.1 - 6.6e-38 129.6 2.0 1e-37 129.0 2.0 1.3 1 0 0 1 1 1 1 HPP family Bul1_N PF04425.12 KSA02056.1 - 1.5e-30 106.4 3.6 2.3e-30 105.8 3.6 1.2 1 0 0 1 1 1 1 Bul1 N terminus Bul1_C PF04426.12 KSA02056.1 - 9.7e-17 61.3 9.0 2.4e-08 33.7 0.2 3.1 3 1 1 4 4 4 2 Bul1 C terminus PEPCK_ATP PF01293.20 KSA02057.1 - 4.6e-217 721.2 0.0 5.5e-217 721.0 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.6 KSA02057.1 - 0.14 12.3 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KSA02057.1 - 0.19 11.3 0.0 0.55 9.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain p450 PF00067.22 KSA02058.1 - 1e-64 219.0 0.0 1.3e-64 218.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KSA02059.1 - 1.1e-63 215.6 0.0 1.5e-63 215.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF485 PF04341.12 KSA02059.1 - 0.03 14.3 0.4 0.072 13.0 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF485 ABG_transport PF03806.13 KSA02059.1 - 0.28 9.4 0.2 0.39 8.9 0.2 1.1 1 0 0 1 1 1 0 AbgT putative transporter family Nup192 PF11894.8 KSA02060.1 - 0 1724.0 91.1 0 1723.8 91.1 1.0 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 Retrotrans_gag PF03732.17 KSA02061.1 - 9e-06 25.9 0.2 1.7e-05 25.0 0.2 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein AA_permease PF00324.21 KSA02062.1 - 2.2e-111 372.8 37.4 2.7e-111 372.5 37.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KSA02062.1 - 9.7e-24 84.0 38.3 1.3e-23 83.6 38.3 1.1 1 0 0 1 1 1 1 Amino acid permease DPBB_1 PF03330.18 KSA02063.1 - 3.2e-09 37.0 0.1 8.9e-09 35.5 0.1 1.9 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 KSA02063.1 - 0.003 17.4 0.2 0.0062 16.4 0.2 1.5 1 0 0 1 1 1 1 Barwin family Cerato-platanin PF07249.12 KSA02063.1 - 0.0036 17.4 1.5 0.0071 16.5 0.1 2.1 2 1 1 3 3 3 1 Cerato-platanin PIN_4 PF13638.6 KSA02064.1 - 2e-16 60.4 0.2 8e-16 58.5 0.2 2.1 1 0 0 1 1 1 1 PIN domain Glucan_synthase PF02364.15 KSA02065.1 - 0 1315.1 3.4 0 1314.6 3.4 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 KSA02065.1 - 2.8e-37 127.9 9.1 8.2e-36 123.2 9.1 3.0 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Glyco_hydro_72 PF03198.14 KSA02067.1 - 6.9e-146 485.5 8.8 9.4e-146 485.0 8.8 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 KSA02067.1 - 6.8e-28 97.2 4.1 2.1e-27 95.6 4.1 1.9 1 0 0 1 1 1 1 X8 domain Cellulase PF00150.18 KSA02067.1 - 2.4e-05 23.9 0.3 0.00027 20.4 0.3 2.1 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.17 KSA02067.1 - 0.01 15.0 0.5 0.03 13.4 0.5 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Gsf2 PF11055.8 KSA02069.1 - 4.3e-144 479.9 0.0 4.9e-144 479.7 0.0 1.0 1 0 0 1 1 1 1 Glucose signalling factor 2 Meth_synt_2 PF01717.18 KSA02070.1 - 5.3e-154 512.3 0.0 2.4e-148 493.7 0.0 2.4 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 KSA02070.1 - 6.6e-118 393.8 0.0 2.9e-111 371.9 0.0 2.8 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain YolD PF08863.10 KSA02070.1 - 0.064 13.3 0.2 0.15 12.1 0.2 1.6 1 0 0 1 1 1 0 YolD-like protein SEP PF08059.13 KSA02071.1 - 1.2e-22 80.2 0.0 3.3e-22 78.8 0.0 1.8 1 0 0 1 1 1 1 SEP domain UBX PF00789.20 KSA02071.1 - 1.8e-14 53.7 0.0 3.9e-14 52.6 0.0 1.6 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 KSA02071.1 - 3.3e-09 36.4 0.5 5.6e-09 35.7 0.5 1.4 1 0 0 1 1 1 1 UBA-like domain SPT2 PF08243.11 KSA02071.1 - 0.38 11.3 6.9 0.97 10.0 6.9 1.6 1 0 0 1 1 1 0 SPT2 chromatin protein Chorismate_bind PF00425.18 KSA02073.1 - 9.7e-91 303.9 0.0 1.2e-90 303.6 0.0 1.1 1 0 0 1 1 1 1 chorismate binding enzyme POR PF01558.18 KSA02073.1 - 0.047 13.8 0.0 0.088 12.9 0.0 1.4 1 0 0 1 1 1 0 Pyruvate ferredoxin/flavodoxin oxidoreductase DUF2312 PF10073.9 KSA02073.1 - 0.053 13.2 0.0 0.18 11.5 0.0 1.9 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2312) Myb_DNA-bind_6 PF13921.6 KSA02074.1 - 2.6e-09 37.2 1.4 3.6e-08 33.5 0.3 2.6 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KSA02074.1 - 3e-08 33.7 1.6 2.5e-06 27.6 0.1 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain PTH2 PF01981.16 KSA02075.1 - 6.5e-42 142.5 0.1 9.1e-42 142.0 0.1 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Ost5 PF05251.12 KSA02075.1 - 0.061 13.6 0.1 0.11 12.8 0.1 1.4 1 0 0 1 1 1 0 Oligosaccharyltransferase subunit 5 DnaJ PF00226.31 KSA02076.1 - 5.1e-12 45.7 0.5 5.1e-12 45.7 0.5 2.9 3 1 1 4 4 4 1 DnaJ domain MCU PF04678.13 KSA02076.1 - 1.2 9.2 6.1 2.5 8.2 6.1 1.5 1 0 0 1 1 1 0 Mitochondrial calcium uniporter TatD_DNase PF01026.21 KSA02077.1 - 1.1e-40 139.6 0.0 2.5e-39 135.2 0.0 2.1 1 1 0 1 1 1 1 TatD related DNase MOZ_SAS PF01853.18 KSA02078.1 - 3.6e-72 241.8 0.6 6.6e-72 240.9 0.6 1.4 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KSA02078.1 - 2.4e-21 75.1 5.5 6.3e-21 73.7 5.5 1.7 1 0 0 1 1 1 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 KSA02078.1 - 0.058 13.8 0.0 0.13 12.7 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PP2C PF00481.21 KSA02079.1 - 6.5e-73 245.5 0.0 2.2e-71 240.5 0.0 2.5 1 1 0 1 1 1 1 Protein phosphatase 2C RRM_1 PF00076.22 KSA02080.1 - 0.00046 20.0 0.0 0.001 18.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CENP-B_dimeris PF09026.10 KSA02080.1 - 1.1 9.7 6.6 2.1 8.8 6.6 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Sec61_beta PF03911.16 KSA02081.1 - 2.4e-19 69.1 1.1 2.9e-19 68.8 1.1 1.1 1 0 0 1 1 1 1 Sec61beta family Podoplanin PF05808.11 KSA02081.1 - 0.17 11.9 0.2 0.18 11.9 0.2 1.1 1 0 0 1 1 1 0 Podoplanin tRNA-synt_2b PF00587.25 KSA02082.1 - 3.4e-34 118.4 0.0 6.5e-34 117.4 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KSA02082.1 - 0.0003 20.9 0.0 0.00078 19.5 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.20 KSA02082.1 - 0.014 14.5 0.1 0.027 13.5 0.1 1.4 1 0 0 1 1 1 0 tRNA synthetases class II (D, K and N) DUF883 PF05957.13 KSA02083.1 - 0.0086 16.7 0.3 0.0086 16.7 0.3 6.9 1 1 7 8 8 8 3 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.18 KSA02083.1 - 0.17 11.8 39.6 0.11 12.4 12.3 4.0 1 1 2 3 3 3 0 Apolipoprotein A1/A4/E domain MFS_1 PF07690.16 KSA02084.1 - 9e-34 116.9 27.3 1.4e-33 116.3 25.5 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1189 PF06691.11 KSA02084.1 - 0.0088 15.6 0.2 0.035 13.7 0.2 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1189) Cytomega_TRL10 PF06084.11 KSA02084.1 - 0.027 14.5 0.2 0.06 13.4 0.2 1.6 1 0 0 1 1 1 0 Cytomegalovirus TRL10 protein BRI3BP PF14965.6 KSA02084.1 - 0.11 11.9 0.1 0.11 11.9 0.1 2.4 2 1 1 3 3 3 0 Negative regulator of p53/TP53 DUF4448 PF14610.6 KSA02084.1 - 0.17 11.7 0.1 0.48 10.2 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF3295 PF11702.8 KSA02085.1 - 4.2e-05 23.1 31.2 0.00035 20.1 9.4 4.9 2 1 1 4 4 4 2 Protein of unknown function (DUF3295) DnaJ PF00226.31 KSA02086.1 - 4.1e-23 81.3 0.3 1.2e-22 79.7 0.3 1.9 1 0 0 1 1 1 1 DnaJ domain zf-C2H2_jaz PF12171.8 KSA02086.1 - 6.4e-10 39.1 15.0 3.7e-08 33.4 9.1 2.7 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KSA02086.1 - 7.3e-09 35.9 5.4 0.00056 20.2 2.1 2.6 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 KSA02086.1 - 3.1e-08 33.7 13.3 4e-07 30.2 4.0 3.4 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KSA02086.1 - 0.00065 20.3 6.4 0.58 11.1 1.2 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger OTT_1508_deam PF14441.6 KSA02086.1 - 0.031 14.3 1.1 0.49 10.4 0.4 2.5 2 0 0 2 2 2 0 OTT_1508-like deaminase DUF2256 PF10013.9 KSA02086.1 - 0.075 13.2 0.7 4.3 7.6 0.0 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2 PF00096.26 KSA02086.1 - 0.079 13.5 10.1 0.6 10.7 2.1 3.1 3 0 0 3 3 3 0 Zinc finger, C2H2 type Acyl_transf_1 PF00698.21 KSA02086.1 - 0.1 12.1 0.6 0.2 11.1 0.6 1.4 1 0 0 1 1 1 0 Acyl transferase domain DUF1318 PF07027.12 KSA02086.1 - 1.5 9.3 6.3 0.21 12.0 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1318) zf-C2H2_6 PF13912.6 KSA02086.1 - 4.8 7.3 11.0 6.8 6.8 4.5 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger G-patch PF01585.23 KSA02087.1 - 2.1e-11 43.6 1.8 2.1e-11 43.6 1.8 2.4 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 KSA02087.1 - 0.032 14.3 0.4 0.27 11.4 0.2 2.8 2 0 0 2 2 2 0 G-patch domain Peptidase_C54 PF03416.19 KSA02088.1 - 6.4e-83 278.4 0.0 8.7e-83 277.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 Ssu72 PF04722.13 KSA02089.1 - 4.2e-71 238.5 1.0 4.7e-71 238.3 1.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein PRORP PF16953.5 KSA02089.1 - 0.021 14.3 4.8 0.12 11.9 0.4 2.2 1 1 1 2 2 2 0 Protein-only RNase P EF-hand_10 PF14788.6 KSA02089.1 - 0.073 13.0 0.2 0.2 11.5 0.2 1.7 1 0 0 1 1 1 0 EF hand POP1 PF06978.11 KSA02090.1 - 5.7e-75 251.8 7.9 1.2e-74 250.8 7.9 1.5 1 0 0 1 1 1 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 KSA02090.1 - 3.8e-27 94.5 0.7 8e-27 93.4 0.7 1.6 1 0 0 1 1 1 1 POPLD (NUC188) domain GCV_T PF01571.21 KSA02090.1 - 0.0029 17.0 0.0 0.006 16.0 0.0 1.5 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain Flocculin_t3 PF13928.6 KSA02091.1 - 0.0022 18.4 8.7 0.0022 18.4 8.7 3.2 1 1 1 2 2 2 1 Flocculin type 3 repeat DUF1505 PF07403.11 KSA02091.1 - 0.008 16.4 2.7 0.0096 16.1 2.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1505) UCH PF00443.29 KSA02092.1 - 3.7e-47 161.0 5.7 3.7e-47 161.0 5.7 2.3 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KSA02092.1 - 1.5e-11 44.5 5.9 1.5e-11 44.5 5.9 2.7 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase SWIM PF04434.17 KSA02093.1 - 0.02 14.6 3.4 0.3 10.8 0.0 2.4 2 0 0 2 2 2 0 SWIM zinc finger DUF4404 PF14357.6 KSA02093.1 - 0.2 12.3 4.6 0.16 12.6 2.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) PH_18 PF18469.1 KSA02094.1 - 2.9e-50 169.9 2.1 2.9e-50 169.9 2.1 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain Rtt106 PF08512.12 KSA02094.1 - 2.6e-21 75.8 0.5 5.9e-21 74.7 0.5 1.6 1 0 0 1 1 1 1 Histone chaperone Rttp106-like DUF2542 PF10808.8 KSA02094.1 - 0.15 12.5 0.0 0.26 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2542) Aminotran_1_2 PF00155.21 KSA02096.1 - 2.7e-17 63.0 0.0 3.5e-17 62.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 KSA02096.1 - 0.00047 19.1 0.0 0.00087 18.2 0.0 1.3 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase CHASE PF03924.13 KSA02096.1 - 0.2 11.6 0.0 0.31 11.0 0.0 1.2 1 0 0 1 1 1 0 CHASE domain PAP2 PF01569.21 KSA02097.1 - 5.8e-21 74.7 1.6 7.9e-21 74.3 1.6 1.2 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 KSA02097.1 - 0.011 15.5 0.4 0.037 13.7 0.4 1.8 1 1 0 1 1 1 0 PAP2 superfamily PAP2_C PF14360.6 KSA02097.1 - 0.11 13.0 2.3 0.27 11.8 2.3 1.7 1 1 0 1 1 1 0 PAP2 superfamily C-terminal PX PF00787.24 KSA02098.1 - 2.7e-11 43.4 0.7 6.8e-11 42.1 0.2 1.9 2 0 0 2 2 2 1 PX domain KxDL PF10241.9 KSA02098.1 - 0.33 11.3 16.6 1.7 8.9 10.8 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein ISG65-75 PF11727.8 KSA02098.1 - 0.4 9.9 4.8 0.64 9.2 4.8 1.3 1 0 0 1 1 1 0 Invariant surface glycoprotein Snapin_Pallidin PF14712.6 KSA02098.1 - 1.3 9.5 15.6 1.9 9.0 12.7 2.4 2 0 0 2 2 2 0 Snapin/Pallidin DUF1664 PF07889.12 KSA02098.1 - 2.6 8.1 7.9 4 7.5 5.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 KSA02098.1 - 6.1 7.2 9.4 28 5.1 7.5 2.7 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) HIP1_clath_bdg PF16515.5 KSA02098.1 - 7.6 7.2 18.1 70 4.1 15.0 2.5 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF2417 PF10329.9 KSA02099.1 - 6.3e-73 245.1 5.8 9.6e-73 244.5 5.8 1.2 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Abhydrolase_1 PF00561.20 KSA02099.1 - 1.7e-07 31.2 0.0 3.2e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KSA02099.1 - 0.0001 23.0 0.0 0.00016 22.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 KSA02099.1 - 0.0016 18.6 0.0 0.0026 17.9 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Hydrolase_4 PF12146.8 KSA02099.1 - 0.15 11.3 0.0 0.26 10.5 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 FHA PF00498.26 KSA02100.1 - 3.2e-13 49.8 0.0 6.4e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 FHA domain zf-RING_11 PF17123.5 KSA02100.1 - 5.4e-12 45.2 6.7 1e-11 44.3 6.7 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 KSA02100.1 - 1.8e-07 31.4 9.9 3.5e-07 30.5 9.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KSA02100.1 - 0.00071 19.4 10.0 0.0013 18.5 10.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KSA02100.1 - 0.0011 18.7 9.1 0.0021 17.9 9.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Yop-YscD_cpl PF16697.5 KSA02100.1 - 0.0016 18.7 0.0 0.0035 17.6 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-RING_5 PF14634.6 KSA02100.1 - 0.0042 17.0 7.2 0.0077 16.2 7.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 KSA02100.1 - 0.014 15.6 5.7 0.038 14.3 5.7 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KSA02100.1 - 0.017 15.2 3.2 0.032 14.3 3.2 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 KSA02100.1 - 0.52 10.4 9.3 1.1 9.4 9.3 1.6 1 0 0 1 1 1 0 RING-type zinc-finger PHD PF00628.29 KSA02100.1 - 0.56 10.2 9.4 0.15 12.0 5.7 2.0 2 0 0 2 2 2 0 PHD-finger Sugar_tr PF00083.24 KSA02101.1 - 2.9e-94 316.5 21.9 3.4e-94 316.3 21.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KSA02101.1 - 2e-21 76.3 21.9 1.1e-18 67.3 17.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KSA02101.1 - 1.5e-07 30.3 14.1 1.5e-06 27.1 0.3 2.5 2 1 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.7 KSA02101.1 - 8.9e-05 21.5 1.0 8.9e-05 21.5 1.0 1.6 2 0 0 2 2 2 1 MFS_1 like family PNGaseA PF12222.8 KSA02103.1 - 7.9e-124 413.8 2.5 7.9e-124 413.8 2.5 1.9 1 1 1 2 2 2 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A Vps35 PF03635.17 KSA02104.1 - 9.6e-265 880.6 32.8 1.2e-264 880.3 32.8 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 MalM PF07148.12 KSA02104.1 - 0.011 15.5 0.0 0.029 14.2 0.0 1.7 1 0 0 1 1 1 0 Maltose operon periplasmic protein precursor (MalM) Nucleos_tra2_C PF07662.13 KSA02105.1 - 7.4e-63 212.1 3.7 7.4e-63 212.1 3.7 2.1 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 KSA02105.1 - 6.9e-24 84.3 14.6 1e-23 83.7 3.4 3.3 3 0 0 3 3 3 2 Na+ dependent nucleoside transporter N-terminus Tim17 PF02466.19 KSA02105.1 - 0.5 10.8 6.9 1.4 9.3 0.5 3.2 3 1 0 3 3 3 0 Tim17/Tim22/Tim23/Pmp24 family ATG2_CAD PF13329.6 KSA02106.1 - 1.5e-49 167.7 5.5 2.3e-49 167.1 0.4 3.2 2 0 0 2 2 2 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.11 KSA02106.1 - 2e-27 95.3 0.1 6.4e-27 93.7 0.1 1.9 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain AMIN PF11741.8 KSA02106.1 - 0.19 11.9 3.0 14 5.9 0.1 3.3 2 0 0 2 2 2 0 AMIN domain Las1 PF04031.13 KSA02107.1 - 8.4e-47 159.1 0.0 1.7e-46 158.1 0.0 1.5 1 0 0 1 1 1 1 Las1-like DUF1706 PF08020.11 KSA02107.1 - 0.053 13.4 0.4 0.12 12.3 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1706) Fungal_trans PF04082.18 KSA02108.1 - 1.4e-11 44.0 5.8 3.6e-11 42.6 5.8 1.8 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KSA02108.1 - 3.4e-06 27.1 10.7 6.3e-06 26.2 10.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.25 KSA02109.1 - 2.1e-21 76.3 0.0 3.8e-16 59.1 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KSA02109.1 - 2.5e-13 50.1 0.0 1.4e-09 37.9 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KSA02109.1 - 1e-11 45.1 0.0 1.5e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KSA02109.1 - 0.0031 16.7 0.0 0.0045 16.2 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KSA02109.1 - 0.025 14.0 0.0 0.03 13.7 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Gpr1_Fun34_YaaH PF01184.19 KSA02110.1 - 1.1e-77 260.3 24.4 1.3e-77 260.1 24.4 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family SLATT_1 PF18181.1 KSA02110.1 - 0.66 9.9 3.4 1.3 9.0 2.8 1.8 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 Gpr1_Fun34_YaaH PF01184.19 KSA02111.1 - 3e-80 268.7 26.5 3.5e-80 268.5 26.5 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Mg_trans_NIPA PF05653.14 KSA02112.1 - 2.8e-12 46.4 17.0 7e-09 35.2 1.8 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA DUF3094 PF11293.8 KSA02112.1 - 0.53 10.0 0.0 0.53 10.0 0.0 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF3094) CcmD PF04995.14 KSA02112.1 - 0.98 9.5 2.6 6 7.0 2.6 2.4 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) DUF1077 PF06417.12 KSA02112.1 - 4.2 7.4 6.5 1.8 8.6 0.6 3.0 2 1 0 3 3 3 0 Protein of unknown function (DUF1077) CDC14 PF08045.11 KSA02113.1 - 2.9e-45 154.6 8.2 1.9e-39 135.5 5.7 2.9 1 1 1 2 2 2 2 Cell division control protein 14, SIN component MDM10 PF12519.8 KSA02114.1 - 3.7e-154 514.1 12.5 4.2e-154 513.8 12.5 1.0 1 0 0 1 1 1 1 Mitochondrial distribution and morphology protein 10 DUF835 PF05763.12 KSA02114.1 - 0.051 13.3 0.3 0.44 10.3 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF835) Mit_ribos_Mrp51 PF11709.8 KSA02115.1 - 3.8e-61 207.7 4.7 4.1e-59 201.0 4.7 2.1 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit Pkinase PF00069.25 KSA02117.1 - 1.3e-65 221.4 0.0 1.9e-65 220.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KSA02117.1 - 5.8e-49 166.7 0.0 8.9e-49 166.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KSA02117.1 - 2.1e-06 26.9 0.9 0.00015 20.8 0.9 2.3 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KSA02117.1 - 3.4e-05 23.3 0.3 0.00062 19.2 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KSA02117.1 - 7.1e-05 21.8 0.0 7.1e-05 21.8 0.0 1.9 3 0 0 3 3 3 1 Fungal protein kinase APH PF01636.23 KSA02117.1 - 0.032 14.2 0.0 0.075 12.9 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 KSA02117.1 - 0.054 13.1 0.0 0.15 11.7 0.0 1.7 1 1 0 1 1 1 0 RIO1 family IGPD PF00475.18 KSA02118.1 - 1.7e-59 200.3 0.5 2.5e-59 199.7 0.5 1.3 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase SpoU_methylase PF00588.19 KSA02119.1 - 6.5e-22 78.2 0.0 1.2e-21 77.4 0.0 1.4 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 KSA02119.1 - 6.4e-16 58.4 0.2 2.6e-15 56.4 0.0 2.3 3 0 0 3 3 3 1 RNA 2'-O ribose methyltransferase substrate binding DUF676 PF05057.14 KSA02120.1 - 8.9e-31 107.1 0.0 1.4e-30 106.4 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 KSA02120.1 - 0.00064 19.6 0.0 0.001 19.0 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF818 PF05677.12 KSA02120.1 - 0.0054 15.7 0.6 0.044 12.7 0.1 2.1 2 0 0 2 2 2 1 Chlamydia CHLPS protein (DUF818) Lipase_3 PF01764.25 KSA02120.1 - 0.0093 15.8 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.13 KSA02120.1 - 0.033 13.9 0.0 0.065 12.9 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein PE-PPE PF08237.11 KSA02120.1 - 0.074 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain Abhydrolase_1 PF00561.20 KSA02120.1 - 0.31 10.7 2.4 1.5 8.4 2.4 2.2 1 1 0 1 1 1 0 alpha/beta hydrolase fold Ysc84 PF04366.12 KSA02122.1 - 6e-42 142.4 0.2 9.4e-42 141.8 0.2 1.3 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_1 PF00018.28 KSA02122.1 - 9.1e-16 57.2 0.1 1.7e-15 56.3 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KSA02122.1 - 1.4e-12 47.1 0.0 2.8e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KSA02122.1 - 5.8e-11 42.1 0.0 1.1e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain 2-Hacid_dh_C PF02826.19 KSA02123.1 - 1.5e-44 151.4 0.0 1.9e-44 151.2 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 KSA02123.1 - 0.0028 17.8 0.0 0.0041 17.3 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh PF00389.30 KSA02124.1 - 2.3e-17 62.9 0.0 3e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain CoA_transf_3 PF02515.17 KSA02125.1 - 4.2e-42 144.6 0.0 3e-41 141.8 0.0 2.2 2 1 1 3 3 3 1 CoA-transferase family III SnoaL_2 PF12680.7 KSA02126.1 - 0.0046 17.6 0.0 0.005 17.4 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain Abhydrolase_1 PF00561.20 KSA02127.1 - 5.1e-17 62.4 0.0 6.3e-13 49.0 0.0 2.0 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KSA02127.1 - 6.6e-11 43.2 0.0 9.3e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KSA02127.1 - 5.7e-09 35.6 0.0 6.8e-09 35.3 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF676 PF05057.14 KSA02127.1 - 0.00076 19.0 0.1 0.0012 18.5 0.1 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 KSA02127.1 - 0.00099 18.9 0.5 0.055 13.2 0.1 2.3 1 1 0 2 2 2 1 PGAP1-like protein PAF-AH_p_II PF03403.13 KSA02127.1 - 0.0015 17.2 0.2 0.0087 14.6 0.2 2.0 2 0 0 2 2 2 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_2 PF02230.16 KSA02127.1 - 0.0018 18.1 0.1 0.018 14.9 0.0 2.2 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Chlorophyllase2 PF12740.7 KSA02127.1 - 0.0018 17.3 0.2 0.0062 15.5 0.2 1.8 1 1 0 1 1 1 1 Chlorophyllase enzyme Thioesterase PF00975.20 KSA02127.1 - 0.0022 18.2 0.0 0.0024 18.0 0.0 1.4 1 1 0 1 1 1 1 Thioesterase domain BAAT_C PF08840.11 KSA02127.1 - 0.0044 17.0 0.1 0.01 15.7 0.1 1.6 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal UPF0227 PF05728.12 KSA02127.1 - 0.013 15.4 0.1 0.02 14.9 0.1 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0227) DUF915 PF06028.11 KSA02127.1 - 0.048 13.0 0.2 0.48 9.7 0.0 2.3 3 0 0 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF915) Palm_thioest PF02089.15 KSA02127.1 - 0.054 13.3 0.0 0.063 13.1 0.0 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Abhydrolase_3 PF07859.13 KSA02127.1 - 0.1 12.4 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Fungal_trans PF04082.18 KSA02128.1 - 4.6e-18 65.2 1.3 1.1e-17 64.0 1.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KSA02128.1 - 2.4e-08 34.0 11.0 4.5e-08 33.1 11.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dioxygenase_C PF00775.21 KSA02129.1 - 1.4e-47 161.5 0.0 1.9e-47 161.0 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 KSA02129.1 - 2.3e-24 85.1 0.1 3.6e-24 84.4 0.1 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 KSA02129.1 - 3.6e-06 27.2 0.0 1.2e-05 25.5 0.0 1.8 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain SpaA PF17802.1 KSA02129.1 - 0.084 13.2 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 Prealbumin-like fold domain FAD_binding_3 PF01494.19 KSA02130.1 - 1e-85 288.0 0.0 8.8e-49 166.6 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Phe_hydrox_dim PF07976.12 KSA02130.1 - 7.4e-42 143.2 0.0 1.5e-41 142.2 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain NAD_binding_8 PF13450.6 KSA02130.1 - 0.00072 19.7 0.0 0.0018 18.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KSA02130.1 - 0.00089 18.1 0.0 0.0014 17.4 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 KSA02130.1 - 0.0015 17.8 0.0 0.0026 17.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KSA02130.1 - 0.0016 18.1 0.1 0.0088 15.7 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KSA02130.1 - 0.0049 16.1 0.1 0.016 14.5 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KSA02130.1 - 0.02 14.2 0.0 0.04 13.1 0.0 1.4 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.24 KSA02130.1 - 0.044 12.9 0.0 0.067 12.3 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.22 KSA02130.1 - 0.068 12.2 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A SE PF08491.10 KSA02130.1 - 0.17 10.9 0.0 3.8 6.5 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase AlaDh_PNT_C PF01262.21 KSA02130.1 - 0.23 10.7 0.0 0.38 10.0 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Arm PF00514.23 KSA02131.1 - 9.7e-75 244.6 33.7 9.6e-12 44.5 0.1 11.3 11 1 1 12 12 12 8 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KSA02131.1 - 2.5e-20 72.6 17.4 0.00031 21.2 0.1 8.5 8 1 1 9 9 8 5 HEAT-like repeat HEAT_2 PF13646.6 KSA02131.1 - 1e-15 57.8 10.2 0.0044 17.4 0.1 6.9 3 2 4 7 7 7 5 HEAT repeats HEAT PF02985.22 KSA02131.1 - 1e-13 50.3 19.5 0.037 14.3 0.1 9.0 9 0 0 9 9 8 4 HEAT repeat Adaptin_N PF01602.20 KSA02131.1 - 2.1e-11 43.1 7.3 2.3e-07 29.8 1.5 2.6 1 1 1 2 2 2 2 Adaptin N terminal region KAP PF05804.12 KSA02131.1 - 9.3e-10 37.3 1.1 7.4e-09 34.3 0.4 2.7 1 1 1 2 2 2 2 Kinesin-associated protein (KAP) Arm_2 PF04826.13 KSA02131.1 - 3.1e-06 26.9 13.4 0.0004 19.9 4.1 3.6 2 1 2 4 4 4 3 Armadillo-like Vac14_Fab1_bd PF12755.7 KSA02131.1 - 4.3e-05 24.0 0.2 0.44 11.2 0.0 3.3 1 1 0 2 2 2 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KSA02131.1 - 4.5e-05 23.6 10.2 0.047 13.7 0.3 4.8 2 2 3 5 5 5 3 non-SMC mitotic condensation complex subunit 1 V-ATPase_H_C PF11698.8 KSA02131.1 - 0.00015 21.8 4.2 0.35 11.0 0.0 4.8 3 1 4 7 7 7 1 V-ATPase subunit H DUF5578 PF17741.1 KSA02131.1 - 0.00025 20.5 4.7 0.45 9.9 0.1 4.1 2 1 2 4 4 4 2 Family of unknown function (DUF5578) DUF3361 PF11841.8 KSA02131.1 - 0.0022 18.0 11.0 0.013 15.4 0.2 4.7 2 1 2 5 5 5 1 Domain of unknown function (DUF3361) Tti2 PF10521.9 KSA02131.1 - 0.0079 15.8 0.2 0.12 11.9 0.0 2.7 3 0 0 3 3 3 1 Tti2 family DUF3110 PF11360.8 KSA02131.1 - 0.16 12.2 0.0 6.4 7.1 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3110) CTNNBL PF08216.11 KSA02131.1 - 0.88 9.8 3.3 9.4 6.5 0.0 3.9 4 0 0 4 4 4 0 Catenin-beta-like, Arm-motif containing nuclear Snf7 PF03357.21 KSA02132.1 - 6.4e-19 68.2 14.3 1.2e-18 67.4 14.3 1.4 1 0 0 1 1 1 1 Snf7 zf-primase PF09329.11 KSA02132.1 - 0.046 13.5 0.1 0.079 12.8 0.1 1.4 1 0 0 1 1 1 0 Primase zinc finger NLE PF08154.12 KSA02132.1 - 0.31 11.6 4.5 0.48 11.0 0.0 2.8 3 0 0 3 3 3 0 NLE (NUC135) domain ParA PF10609.9 KSA02133.1 - 2.7e-94 315.2 0.0 3.2e-94 315.0 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KSA02133.1 - 6.8e-09 35.9 0.0 2.2e-08 34.2 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 KSA02133.1 - 6.2e-06 26.2 0.0 5e-05 23.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain MipZ PF09140.11 KSA02133.1 - 0.00012 21.5 0.0 0.00022 20.6 0.0 1.4 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 KSA02133.1 - 0.00038 19.8 0.1 0.004 16.4 0.1 2.1 2 0 0 2 2 2 1 Anion-transporting ATPase RsgA_GTPase PF03193.16 KSA02133.1 - 0.011 15.7 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase CBP_BcsQ PF06564.12 KSA02133.1 - 0.016 14.7 0.1 0.067 12.7 0.1 1.9 1 1 0 1 1 1 0 Cellulose biosynthesis protein BcsQ TF_Zn_Ribbon PF08271.12 KSA02133.1 - 0.023 14.2 0.4 0.063 12.8 0.4 1.8 1 0 0 1 1 1 0 TFIIB zinc-binding AAA_26 PF13500.6 KSA02133.1 - 0.035 13.9 0.0 0.36 10.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain Fer4_NifH PF00142.18 KSA02133.1 - 0.04 13.3 0.0 0.59 9.5 0.0 2.2 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_25 PF13481.6 KSA02133.1 - 0.041 13.4 0.0 0.07 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KSA02133.1 - 0.1 11.7 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Glyco_hydro_3_C PF01915.22 KSA02134.1 - 1.8e-62 210.9 0.0 2.9e-62 210.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KSA02134.1 - 2e-42 145.7 0.0 2.8e-42 145.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KSA02134.1 - 6.9e-21 74.1 0.0 1.6e-20 73.0 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 KSA02134.1 - 3.9e-19 68.9 0.2 7.6e-19 68.0 0.2 1.4 1 0 0 1 1 1 1 PA14 domain GLEYA PF10528.9 KSA02134.1 - 0.027 14.9 0.1 0.069 13.6 0.1 1.7 1 0 0 1 1 1 0 GLEYA domain DUF3797 PF12677.7 KSA02134.1 - 0.14 12.1 0.0 1.9 8.5 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3797) Ribosomal_S5 PF00333.20 KSA02134.1 - 0.17 11.9 0.1 0.35 10.9 0.1 1.5 1 0 0 1 1 1 0 Ribosomal protein S5, N-terminal domain Nucleoporin2 PF04096.14 KSA02135.1 - 2.8e-40 137.9 0.0 6.7e-40 136.6 0.0 1.7 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nup96 PF12110.8 KSA02135.1 - 4.1e-36 124.6 0.1 3.8e-33 114.9 0.1 2.4 1 1 0 1 1 1 1 Nuclear protein 96 Nucleoporin_FG PF13634.6 KSA02135.1 - 6.6e-14 52.5 109.5 1.7e-09 38.4 24.9 3.8 2 1 3 5 5 5 4 Nucleoporin FG repeat region Clathrin PF00637.20 KSA02135.1 - 0.026 14.4 3.0 0.99 9.3 0.0 3.3 2 1 1 3 3 3 0 Region in Clathrin and VPS YjeF_N PF03853.15 KSA02136.1 - 3.4e-37 127.9 0.0 4.9e-37 127.4 0.0 1.2 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.10 KSA02136.1 - 3.4e-08 34.3 10.0 3.4e-08 34.3 10.0 2.6 2 0 0 2 2 2 1 FDF domain SM-ATX PF14438.6 KSA02136.1 - 0.057 13.6 0.9 0.13 12.4 0.1 2.0 2 0 0 2 2 2 0 Ataxin 2 SM domain LSM PF01423.22 KSA02136.1 - 0.077 12.7 0.0 0.5 10.1 0.0 2.3 2 0 0 2 2 2 0 LSM domain DUF4888 PF16229.5 KSA02136.1 - 0.24 11.4 4.7 0.38 10.7 0.2 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4888) Kinesin PF00225.23 KSA02137.1 - 2e-96 322.9 3.6 3.5e-96 322.0 3.6 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KSA02137.1 - 1.5e-20 73.7 0.5 4.5e-20 72.1 0.1 2.1 2 0 0 2 2 2 1 Microtubule binding STAS PF01740.21 KSA02137.1 - 0.023 14.3 0.1 0.057 13.1 0.1 1.6 1 0 0 1 1 1 0 STAS domain Csm1_N PF18504.1 KSA02137.1 - 0.09 13.1 7.4 0.076 13.4 1.7 2.7 2 0 0 2 2 2 0 Csm1 N-terminal domain SlyX PF04102.12 KSA02137.1 - 0.16 12.6 0.6 12 6.6 0.1 2.7 2 0 0 2 2 2 0 SlyX TSC22 PF01166.18 KSA02137.1 - 0.21 11.9 8.9 4.5 7.6 0.2 3.7 2 1 1 3 3 3 0 TSC-22/dip/bun family Herpes_BLRF2 PF05812.12 KSA02137.1 - 0.82 9.8 4.1 0.53 10.4 0.6 2.5 2 1 0 2 2 2 0 Herpesvirus BLRF2 protein Fez1 PF06818.15 KSA02137.1 - 4.9 7.6 10.2 0.3 11.5 3.5 2.3 3 0 0 3 3 3 0 Fez1 DUF848 PF05852.11 KSA02137.1 - 5.3 7.1 11.2 1.1 9.4 2.0 3.0 2 1 1 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) UBX PF00789.20 KSA02138.1 - 3.1e-13 49.7 0.0 6.4e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 UBX domain PALP PF00291.25 KSA02140.1 - 4.4e-67 226.6 0.0 5.3e-67 226.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 KSA02140.1 - 5.2e-14 52.4 0.1 3.8e-09 36.9 0.0 2.8 2 0 0 2 2 2 2 CBS domain E3_binding PF02817.17 KSA02140.1 - 1.6 9.1 5.4 15 6.1 0.1 3.1 3 0 0 3 3 3 0 e3 binding domain TFIIS_M PF07500.14 KSA02141.1 - 5e-29 101.0 3.4 5e-29 101.0 3.4 1.8 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 KSA02141.1 - 2.8e-18 65.5 7.5 4.4e-18 64.9 7.5 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 KSA02141.1 - 2.6e-09 37.0 2.5 3.2e-09 36.7 0.4 2.3 2 0 0 2 2 2 1 TFIIS helical bundle-like domain Elf1 PF05129.13 KSA02141.1 - 0.065 13.3 2.9 0.18 11.9 2.9 1.8 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like Baculo_LEF5_C PF11792.8 KSA02141.1 - 0.072 12.8 1.4 0.12 12.0 1.4 1.4 1 0 0 1 1 1 0 Baculoviridae late expression factor 5 C-terminal domain DUF3533 PF12051.8 KSA02141.1 - 0.19 10.6 0.3 0.33 9.8 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) LINES_C PF14695.6 KSA02141.1 - 0.27 10.7 1.8 0.27 10.7 0.2 1.9 2 0 0 2 2 2 0 Lines C-terminus CSTF2_hinge PF14327.6 KSA02142.1 - 5.5e-21 74.8 2.8 5.5e-21 74.8 2.8 1.9 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 KSA02142.1 - 7.3e-19 67.4 0.0 1.5e-18 66.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 KSA02142.1 - 0.00059 19.4 1.7 0.0006 19.3 0.3 1.8 2 0 0 2 2 2 1 Transcription termination and cleavage factor C-terminal RRM_occluded PF16842.5 KSA02142.1 - 0.0063 16.3 0.0 0.019 14.8 0.0 1.8 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_7 PF16367.5 KSA02142.1 - 0.16 12.1 0.1 0.75 9.9 0.0 2.3 2 1 0 2 2 2 0 RNA recognition motif WW PF00397.26 KSA02143.1 - 1e-09 38.3 0.1 1.7e-09 37.6 0.1 1.4 1 0 0 1 1 1 1 WW domain DUF2076 PF09849.9 KSA02143.1 - 0.16 12.0 5.7 0.2 11.6 5.7 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) ETC_C1_NDUFA5 PF04716.14 KSA02144.1 - 5.4e-28 96.6 0.2 8.2e-28 96.0 0.2 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region Ras PF00071.22 KSA02145.1 - 6.1e-64 214.5 0.1 7.3e-64 214.3 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KSA02145.1 - 2.2e-37 127.9 0.1 3.4e-37 127.3 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KSA02145.1 - 3.2e-16 59.3 0.0 4e-16 59.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KSA02145.1 - 4e-08 32.9 0.0 4.8e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KSA02145.1 - 1.7e-07 31.0 0.1 5.2e-07 29.4 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KSA02145.1 - 3e-05 24.1 0.1 4.4e-05 23.5 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KSA02145.1 - 8.3e-05 22.5 0.1 0.13 12.1 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 KSA02145.1 - 0.00013 21.4 0.0 0.00016 21.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 KSA02145.1 - 0.00045 19.8 0.0 0.0019 17.7 0.0 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B Septin PF00735.18 KSA02145.1 - 0.0037 16.6 0.5 0.011 15.0 0.1 1.8 2 0 0 2 2 2 1 Septin AAA_7 PF12775.7 KSA02145.1 - 0.0086 15.6 0.0 0.015 14.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 KSA02145.1 - 0.014 15.7 0.2 0.16 12.3 0.1 2.3 1 1 1 2 2 2 0 AAA domain AAA_16 PF13191.6 KSA02145.1 - 0.031 14.7 0.0 0.057 13.8 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain CPT PF07931.12 KSA02145.1 - 0.033 14.0 0.0 0.05 13.5 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein G-alpha PF00503.20 KSA02145.1 - 0.038 13.1 0.5 8.2 5.5 0.1 2.6 1 1 1 2 2 2 0 G-protein alpha subunit AAA_29 PF13555.6 KSA02145.1 - 0.047 13.4 0.3 0.15 11.8 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_24 PF13479.6 KSA02145.1 - 0.088 12.5 0.2 0.32 10.7 0.1 1.9 1 1 1 2 2 2 0 AAA domain MCM PF00493.23 KSA02145.1 - 0.091 11.8 0.0 0.28 10.3 0.0 1.7 2 0 0 2 2 2 0 MCM P-loop domain TniB PF05621.11 KSA02145.1 - 0.1 12.0 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein ABC_tran PF00005.27 KSA02145.1 - 0.13 12.7 0.8 0.32 11.5 0.8 1.8 1 1 0 1 1 1 0 ABC transporter tRNA_synthFbeta PF17759.1 KSA02146.1 - 6.9e-40 136.8 0.0 1.1e-39 136.1 0.0 1.3 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 KSA02146.1 - 3.6e-31 107.2 0.8 1.4e-29 102.2 0.2 2.5 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 KSA02146.1 - 6.4e-25 87.8 0.0 1.1e-24 87.0 0.0 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 KSA02146.1 - 1.3e-18 67.0 0.1 4.5e-16 58.9 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetase B5 domain DUF726 PF05277.12 KSA02147.1 - 3.7e-125 417.4 2.6 5.3e-125 416.9 2.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) ETRAMP PF09716.10 KSA02147.1 - 0.077 13.1 1.9 0.12 12.5 0.1 2.4 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Caudal_act PF04731.12 KSA02147.1 - 0.14 12.5 1.0 3.5 8.0 0.5 2.4 2 0 0 2 2 2 0 Caudal like protein activation region Methyltransf_34 PF11312.8 KSA02148.1 - 1.1e-90 304.0 0.0 1.6e-90 303.5 0.0 1.3 1 0 0 1 1 1 1 Putative SAM-dependent methyltransferase SIR2 PF02146.17 KSA02149.1 - 7.5e-57 192.1 0.0 1.1e-56 191.6 0.0 1.2 1 0 0 1 1 1 1 Sir2 family FbpA PF05833.11 KSA02150.1 - 2.2e-22 79.5 0.3 2.2e-22 79.5 0.3 4.1 3 3 1 5 5 5 2 Fibronectin-binding protein A N-terminus (FbpA) NFACT-R_1 PF05670.13 KSA02150.1 - 1.1e-20 74.3 0.0 4.5e-20 72.3 0.0 2.2 1 0 0 1 1 1 1 NFACT protein RNA binding domain WVELL PF14043.6 KSA02150.1 - 0.037 13.9 0.8 13 5.7 0.1 2.7 2 0 0 2 2 2 0 WVELL protein PDU_like PF15953.5 KSA02150.1 - 0.16 12.0 1.7 0.35 10.9 1.7 1.5 1 0 0 1 1 1 0 Putative propanediol utilisation NFACT-C PF11923.8 KSA02151.1 - 7.7e-34 115.8 2.0 1.2e-33 115.2 0.0 2.0 2 0 0 2 2 2 1 NFACT protein C-terminal domain His_Phos_2 PF00328.22 KSA02152.1 - 2.8e-42 145.4 0.0 3.4e-42 145.2 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) His_Phos_2 PF00328.22 KSA02153.1 - 2.1e-59 201.8 0.0 2.7e-59 201.5 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) GST_C PF00043.25 KSA02154.1 - 4.8e-21 74.8 0.0 9.3e-21 73.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KSA02154.1 - 1.1e-18 67.3 0.0 2.3e-18 66.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KSA02154.1 - 1.9e-11 44.2 0.0 3.6e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KSA02154.1 - 1.7e-10 41.0 0.0 3.7e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KSA02154.1 - 0.00011 22.3 0.1 0.00043 20.4 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KSA02154.1 - 0.037 14.0 0.0 0.069 13.2 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GATase PF00117.28 KSA02155.1 - 1.2e-11 44.7 0.0 2.8e-11 43.6 0.0 1.6 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KSA02155.1 - 0.053 13.3 0.0 0.094 12.4 0.0 1.5 1 1 0 1 1 1 0 Peptidase C26 TMEM247 PF15444.6 KSA02156.1 - 8.6 6.3 10.4 42 4.1 10.4 2.2 1 0 0 1 1 1 0 Transmembrane protein 247 Cyt-b5 PF00173.28 KSA02157.1 - 3.4e-10 39.9 0.0 3.9e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF1730 PF08331.10 KSA02157.1 - 0.16 11.9 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1730) RRM_1 PF00076.22 KSA02158.1 - 1.5e-15 56.8 0.0 2.3e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 KSA02158.1 - 0.13 12.4 0.0 26 5.0 0.0 2.9 3 0 0 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter Ran_BP1 PF00638.18 KSA02159.1 - 2.3e-23 82.8 0.1 4.5e-23 81.8 0.1 1.5 1 0 0 1 1 1 1 RanBP1 domain ArnB_C PF18677.1 KSA02159.1 - 0.051 13.7 0.3 0.051 13.7 0.3 2.9 3 0 0 3 3 3 0 Archaellum regulatory network B, C-terminal domain Methyltransf_31 PF13847.6 KSA02160.1 - 1.4e-23 83.4 0.3 1.7e-23 83.1 0.3 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 KSA02160.1 - 1.2e-05 25.3 0.0 1.4e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KSA02160.1 - 2.8e-05 24.8 0.1 4e-05 24.3 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KSA02160.1 - 3.1e-05 24.6 0.0 7.7e-05 23.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KSA02160.1 - 0.018 14.9 0.0 0.023 14.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain CAF1C_H4-bd PF12265.8 KSA02161.1 - 8.1e-23 80.5 0.0 4.9e-22 78.0 0.1 2.3 3 0 0 3 3 3 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 KSA02161.1 - 3.8e-09 37.0 17.1 0.0034 18.2 1.4 5.2 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KSA02161.1 - 4.7e-08 33.2 7.4 0.034 14.4 0.1 5.5 2 1 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Peptidase_S41 PF03572.18 KSA02161.1 - 0.072 12.7 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Peptidase family S41 Mt_ATP-synt_B PF05405.14 KSA02162.1 - 9.4e-51 171.7 12.5 1.1e-50 171.4 12.5 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) WIF PF02019.18 KSA02162.1 - 0.007 16.1 0.2 0.01 15.5 0.2 1.2 1 0 0 1 1 1 1 WIF domain GAS PF13851.6 KSA02162.1 - 0.011 15.1 11.9 0.015 14.6 11.9 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF5623 PF18536.1 KSA02162.1 - 0.011 16.0 1.4 0.031 14.6 0.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF5623) UBA_6 PF18039.1 KSA02162.1 - 0.15 12.0 0.3 0.32 11.0 0.3 1.4 1 0 0 1 1 1 0 UBA-like domain SLATT_1 PF18181.1 KSA02162.1 - 1.1 9.2 8.3 0.055 13.4 1.5 2.1 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 DivIC PF04977.15 KSA02162.1 - 9.9 6.0 9.8 0.21 11.4 1.0 2.3 1 1 1 2 2 2 0 Septum formation initiator cwf18 PF08315.12 KSA02163.1 - 5.9e-19 69.1 6.3 6.9e-19 68.9 6.3 1.1 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor Sec63 PF02889.16 KSA02164.1 - 2.4e-36 125.3 0.4 3.5e-36 124.7 0.4 1.3 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.29 KSA02164.1 - 2.4e-25 89.3 0.0 5.7e-25 88.1 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KSA02164.1 - 1.5e-12 47.8 0.0 1.5e-12 47.8 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KSA02164.1 - 6.8e-11 42.5 0.0 4.2e-10 40.0 0.0 2.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain UvrD-helicase PF00580.21 KSA02164.1 - 0.00082 19.0 1.1 0.99 8.9 0.0 3.3 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 KSA02164.1 - 0.0026 18.0 0.2 0.12 12.7 0.1 3.0 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KSA02164.1 - 0.028 14.1 0.0 0.064 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KSA02164.1 - 0.071 12.9 0.9 1.6 8.5 0.0 2.7 2 1 1 3 3 3 0 AAA domain Sigma54_activat PF00158.26 KSA02164.1 - 0.15 11.8 0.0 10 5.8 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain Palm_thioest PF02089.15 KSA02165.1 - 6.9e-75 252.0 0.0 8.2e-75 251.8 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF676 PF05057.14 KSA02165.1 - 2.8e-05 23.7 0.0 3.8e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 KSA02165.1 - 0.0019 17.9 0.1 0.072 12.8 0.1 2.4 1 1 0 1 1 1 1 PGAP1-like protein Lipase_2 PF01674.18 KSA02165.1 - 0.15 11.5 0.0 0.75 9.3 0.0 2.0 1 1 0 1 1 1 0 Lipase (class 2) Ribosomal_L1 PF00687.21 KSA02166.1 - 1.5e-43 148.9 5.2 1.9e-43 148.6 5.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family AA_permease_2 PF13520.6 KSA02167.1 - 3.5e-15 55.8 24.2 4.1e-15 55.6 24.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KSA02167.1 - 1.9e-09 36.7 19.5 2.3e-09 36.4 19.5 1.1 1 0 0 1 1 1 1 Amino acid permease UPF0139 PF03669.13 KSA02167.1 - 0.19 11.6 0.9 1.4 8.9 0.1 2.8 2 2 1 3 3 3 0 Uncharacterised protein family (UPF0139) DUF2207 PF09972.9 KSA02167.1 - 9.7 4.8 10.6 89 1.6 10.4 2.0 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) AA_permease_2 PF13520.6 KSA02168.1 - 9.6e-29 100.5 17.8 1.2e-28 100.1 17.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KSA02168.1 - 2e-18 66.3 15.0 2.4e-18 66.0 15.0 1.1 1 0 0 1 1 1 1 Amino acid permease UPF0370 PF13980.6 KSA02168.1 - 1.9 8.6 3.4 59 3.8 2.4 2.8 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0370) CPP1-like PF11833.8 KSA02168.1 - 1.9 8.1 9.3 0.15 11.7 3.8 1.9 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DUF2518 PF10726.9 KSA02168.1 - 2.7 7.6 5.5 7.1 6.3 1.2 2.6 2 0 0 2 2 2 0 Protein of function (DUF2518) Tim17 PF02466.19 KSA02169.1 - 3.9e-30 104.5 7.1 5.2e-30 104.1 7.1 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Pkinase PF00069.25 KSA02170.1 - 3.5e-50 170.8 0.2 1.4e-49 168.8 0.2 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KSA02170.1 - 4.3e-21 75.4 0.0 7.8e-21 74.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KSA02170.1 - 0.00061 19.8 0.0 0.001 19.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KSA02170.1 - 0.0075 15.9 0.3 0.0075 15.9 0.3 1.8 2 0 0 2 2 2 1 Choline/ethanolamine kinase RNA_pol_Rpb4 PF03874.16 KSA02171.1 - 1e-34 119.5 6.0 1.3e-34 119.1 6.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 GCV_T PF01571.21 KSA02171.1 - 0.044 13.1 0.0 0.089 12.1 0.0 1.4 2 0 0 2 2 2 0 Aminomethyltransferase folate-binding domain GTP_EFTU PF00009.27 KSA02172.1 - 2.1e-37 128.6 0.0 3.4e-37 127.9 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 KSA02172.1 - 1.6e-20 73.0 0.0 3.4e-20 72.0 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 KSA02172.1 - 2.4e-18 65.9 0.0 8.1e-18 64.2 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus EFTUD2 PF16004.5 KSA02172.1 - 6e-13 49.4 4.1 2e-12 47.7 4.1 1.8 1 1 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus GTP_EFTU_D2 PF03144.25 KSA02172.1 - 9.1e-13 48.4 0.1 4.1e-12 46.3 0.1 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KSA02172.1 - 1.8e-06 28.0 0.0 4.4e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.6 KSA02172.1 - 2.4e-05 24.3 0.0 6.1e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II Dynamin_N PF00350.23 KSA02172.1 - 0.00057 20.0 0.2 0.2 11.7 0.0 2.5 1 1 1 2 2 2 1 Dynamin family Roc PF08477.13 KSA02172.1 - 0.016 15.4 0.0 2.3 8.4 0.0 2.5 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Septin PF00735.18 KSA02172.1 - 0.023 14.0 0.0 0.051 12.9 0.0 1.5 1 0 0 1 1 1 0 Septin FeoB_N PF02421.18 KSA02172.1 - 0.087 12.3 0.3 10 5.7 0.1 2.6 2 0 0 2 2 2 0 Ferrous iron transport protein B SRPRB PF09439.10 KSA02172.1 - 0.096 12.1 0.1 2.5 7.5 0.1 2.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.17 KSA02172.1 - 0.14 11.9 0.0 24 4.6 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Ras PF00071.22 KSA02172.1 - 0.14 11.7 0.0 0.63 9.6 0.0 2.0 1 1 0 1 1 1 0 Ras family DUF2420 PF10336.9 KSA02173.1 - 2e-28 98.5 5.8 2e-28 98.5 5.8 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2420) SWIRM PF04433.17 KSA02174.1 - 2.3e-31 108.0 0.9 7.5e-30 103.1 0.2 2.6 2 0 0 2 2 2 1 SWIRM domain SWIRM-assoc_1 PF16495.5 KSA02174.1 - 8.4e-23 80.1 2.5 2.1e-22 78.9 2.5 1.6 1 0 0 1 1 1 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 KSA02174.1 - 1.5e-07 31.5 0.0 3.1e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KSA02174.1 - 9.9e-07 28.9 0.2 3.1e-06 27.3 0.2 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain AlphaC_N PF08829.10 KSA02174.1 - 0.085 12.9 0.2 0.21 11.6 0.2 1.7 1 1 0 1 1 1 0 Alpha C protein N terminal Ribosomal_L22 PF00237.19 KSA02175.1 - 1.2e-37 128.2 0.8 1.3e-37 128.2 0.1 1.4 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e UcrQ PF02939.16 KSA02176.1 - 8.4e-31 105.7 1.0 9.7e-31 105.5 1.0 1.0 1 0 0 1 1 1 1 UcrQ family polyprenyl_synt PF00348.17 KSA02177.1 - 7.4e-95 316.8 0.1 9.1e-95 316.6 0.1 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Ebp2 PF05890.12 KSA02178.1 - 9e-89 297.6 24.4 9e-89 297.6 24.4 2.3 1 1 1 2 2 2 1 Eukaryotic rRNA processing protein EBP2 Glyco_transf_15 PF01793.16 KSA02179.1 - 5.5e-110 367.6 11.8 7.7e-110 367.2 11.8 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase AAA PF00004.29 KSA02180.1 - 3.3e-25 89.0 0.0 5.9e-25 88.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KSA02180.1 - 2.7e-06 27.7 0.0 1.1e-05 25.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KSA02180.1 - 2.1e-05 25.0 0.0 4.2e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 KSA02180.1 - 0.001 19.2 0.0 0.012 15.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain Torsin PF06309.11 KSA02180.1 - 0.0019 18.3 0.0 0.0077 16.3 0.0 2.1 2 0 0 2 2 1 1 Torsin AAA_5 PF07728.14 KSA02180.1 - 0.005 16.8 0.1 0.09 12.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 KSA02180.1 - 0.011 15.5 0.0 0.049 13.3 0.0 1.9 3 0 0 3 3 3 0 AAA domain AAA_11 PF13086.6 KSA02180.1 - 0.011 15.5 0.0 0.041 13.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KSA02180.1 - 0.011 16.2 0.1 0.046 14.2 0.0 2.0 2 0 0 2 2 1 0 AAA domain Cytidylate_kin PF02224.18 KSA02180.1 - 0.012 15.3 0.0 0.024 14.4 0.0 1.5 1 0 0 1 1 1 0 Cytidylate kinase DUF815 PF05673.13 KSA02180.1 - 0.014 14.5 0.0 0.029 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RNA_helicase PF00910.22 KSA02180.1 - 0.016 15.6 0.0 0.081 13.3 0.0 2.3 2 0 0 2 2 1 0 RNA helicase AAA_7 PF12775.7 KSA02180.1 - 0.02 14.4 0.0 0.049 13.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 KSA02180.1 - 0.024 14.4 0.0 0.061 13.0 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein NB-ARC PF00931.22 KSA02180.1 - 0.025 13.8 0.0 0.046 12.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain RuvB_N PF05496.12 KSA02180.1 - 0.035 13.8 0.0 0.11 12.2 0.0 1.8 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 KSA02180.1 - 0.037 14.1 0.0 0.13 12.2 0.0 2.1 1 1 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 KSA02180.1 - 0.04 13.1 0.1 0.36 10.0 0.0 2.4 3 1 1 4 4 4 0 KAP family P-loop domain Sigma54_activat PF00158.26 KSA02180.1 - 0.044 13.5 0.0 0.13 12.0 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain TsaE PF02367.17 KSA02180.1 - 0.047 13.7 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE CPT PF07931.12 KSA02180.1 - 0.054 13.3 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Mg_chelatase PF01078.21 KSA02180.1 - 0.11 11.8 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 KSA02180.1 - 0.12 12.3 0.0 0.35 10.8 0.0 1.8 2 0 0 2 2 1 0 NACHT domain AAA_18 PF13238.6 KSA02180.1 - 0.13 12.8 0.0 0.43 11.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KSA02180.1 - 0.14 12.7 0.0 0.35 11.4 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Complex1_51K PF01512.17 KSA02181.1 - 1.3e-47 161.4 0.0 1e-46 158.6 0.0 2.2 3 0 0 3 3 3 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 KSA02181.1 - 2.2e-29 101.3 0.2 6.3e-29 99.9 0.1 1.8 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 KSA02181.1 - 9.5e-07 28.6 0.0 2.3e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 SLBB domain UPF0016 PF01169.19 KSA02182.1 - 1.2e-38 131.3 26.0 1.1e-19 70.6 8.5 2.5 3 0 0 3 3 3 2 Uncharacterized protein family UPF0016 Presenilin PF01080.17 KSA02182.1 - 0.00042 19.2 0.4 0.00083 18.2 0.4 1.4 1 0 0 1 1 1 1 Presenilin Med8 PF10232.9 KSA02183.1 - 2.9e-16 59.8 3.4 3.7e-16 59.4 3.4 1.2 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 Alpha-L-AF_C PF06964.12 KSA02183.1 - 0.0079 16.3 0.1 0.011 15.9 0.1 1.2 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain Rogdi_lz PF10259.9 KSA02183.1 - 0.016 14.7 1.2 0.02 14.4 1.2 1.1 1 0 0 1 1 1 0 Rogdi leucine zipper containing protein Allexi_40kDa PF05549.11 KSA02183.1 - 0.037 13.5 2.6 0.043 13.3 0.7 1.9 1 1 1 2 2 2 0 Allexivirus 40kDa protein NpwBP PF12622.7 KSA02184.1 - 8.1e-08 32.9 6.4 1.6e-06 28.7 6.4 2.8 1 1 0 1 1 1 1 mRNA biogenesis factor Mito_carr PF00153.27 KSA02185.1 - 9.1e-75 246.7 0.4 2.4e-26 91.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3535 PF12054.8 KSA02186.1 - 1.4e-126 423.3 0.3 1.4e-125 420.0 0.1 2.8 4 0 0 4 4 4 1 Domain of unknown function (DUF3535) SNF2_N PF00176.23 KSA02186.1 - 4.1e-64 216.5 0.0 1.3e-63 214.9 0.0 1.8 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KSA02186.1 - 1e-18 67.7 0.1 6.9e-18 65.0 0.0 2.5 3 0 0 3 3 2 1 Helicase conserved C-terminal domain HEAT PF02985.22 KSA02186.1 - 4.3e-14 51.4 0.2 2.4 8.6 0.0 9.7 9 1 0 9 9 9 3 HEAT repeat Vac14_Fab1_bd PF12755.7 KSA02186.1 - 1.1e-08 35.5 0.0 0.036 14.7 0.0 4.6 4 0 0 4 4 4 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 KSA02186.1 - 0.00021 21.7 0.5 20 5.8 0.0 6.8 8 0 0 8 8 8 0 HEAT-like repeat TAF6_C PF07571.13 KSA02186.1 - 0.00028 21.2 0.0 3.6 8.0 0.0 4.8 4 1 0 4 4 4 1 TAF6 C-terminal HEAT repeat domain HEAT_2 PF13646.6 KSA02186.1 - 0.0024 18.2 1.9 1.6 9.2 0.0 5.9 7 1 0 7 7 7 1 HEAT repeats ERCC3_RAD25_C PF16203.5 KSA02186.1 - 0.011 14.9 0.1 0.023 13.9 0.1 1.5 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Cnd1 PF12717.7 KSA02186.1 - 2.8 8.0 11.1 1.2 9.1 0.1 5.0 6 1 1 7 7 7 0 non-SMC mitotic condensation complex subunit 1 DUF3385 PF11865.8 KSA02186.1 - 3.5 7.5 8.2 7.3 6.5 0.1 4.2 6 0 0 6 6 6 0 Domain of unknown function (DUF3385) Ccdc124 PF06244.12 KSA02187.1 - 6.7e-31 107.5 21.5 6.7e-31 107.5 21.5 2.4 2 1 0 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 HMGL-like PF00682.19 KSA02188.1 - 9.1e-84 281.1 0.3 1.2e-83 280.7 0.3 1.2 1 0 0 1 1 1 1 HMGL-like Mur_ligase_M PF08245.12 KSA02190.1 - 0.00052 20.1 2.2 0.01 15.9 0.2 3.1 2 1 0 2 2 2 1 Mur ligase middle domain Mur_ligase_C PF02875.21 KSA02190.1 - 0.0074 16.5 0.0 0.018 15.3 0.0 1.7 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain OGG_N PF07934.12 KSA02191.1 - 1.1e-33 115.8 4.4 1.2e-33 115.7 3.1 1.7 2 0 0 2 2 2 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 KSA02191.1 - 1.4e-15 57.7 0.0 2.4e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KSA02191.1 - 0.017 14.9 0.0 0.038 13.9 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif MgsA_C PF12002.8 KSA02192.1 - 1.3e-56 191.1 0.0 3.6e-56 189.7 0.0 1.8 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 KSA02192.1 - 2.8e-21 75.6 0.2 9e-21 74.0 0.2 1.9 1 0 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 KSA02192.1 - 1e-16 61.6 0.1 2.2e-16 60.5 0.1 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KSA02192.1 - 3.9e-15 56.0 0.0 6.7e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KSA02192.1 - 8e-08 32.4 0.2 1e-06 28.8 0.1 2.7 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 KSA02192.1 - 1.5e-07 31.3 0.0 6.5e-07 29.2 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_14 PF13173.6 KSA02192.1 - 1.5e-06 28.3 0.1 6.9e-06 26.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.14 KSA02192.1 - 1.6e-05 25.1 0.0 6.9e-05 23.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KSA02192.1 - 0.00014 22.3 0.2 0.16 12.3 0.0 2.6 1 1 1 2 2 2 2 AAA ATPase domain Mg_chelatase PF01078.21 KSA02192.1 - 0.00038 19.9 0.0 0.078 12.3 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Viral_helicase1 PF01443.18 KSA02192.1 - 0.0014 18.4 0.3 0.0051 16.6 0.0 2.1 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_3 PF07726.11 KSA02192.1 - 0.0034 17.3 0.0 0.031 14.2 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KSA02192.1 - 0.0042 17.6 1.9 0.046 14.3 0.0 3.0 3 0 0 3 3 2 1 AAA domain Sigma54_activ_2 PF14532.6 KSA02192.1 - 0.029 14.5 0.0 0.075 13.1 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain TIP49 PF06068.13 KSA02192.1 - 0.031 13.5 0.0 0.091 11.9 0.0 1.7 2 0 0 2 2 2 0 TIP49 P-loop domain Zn-C2H2_12 PF18112.1 KSA02192.1 - 0.056 13.9 0.6 0.16 12.5 0.6 1.8 1 0 0 1 1 1 0 Autophagy receptor zinc finger-C2H2 domain AAA_22 PF13401.6 KSA02192.1 - 0.086 13.1 0.3 3.1 8.1 0.1 2.5 1 1 1 2 2 2 0 AAA domain SRAP PF02586.14 KSA02193.1 - 2.1e-49 168.0 0.2 7.6e-49 166.2 0.2 1.7 1 1 0 1 1 1 1 SOS response associated peptidase (SRAP) MRP-S28 PF10213.9 KSA02194.1 - 2.1e-39 134.9 2.7 2.1e-39 134.9 2.7 2.0 3 0 0 3 3 3 1 Mitochondrial ribosomal subunit protein AreA_N PF07573.11 KSA02194.1 - 0.041 14.5 0.6 0.1 13.3 0.6 1.6 1 0 0 1 1 1 0 Nitrogen regulatory protein AreA N terminus ECM11 PF15463.6 KSA02194.1 - 0.089 13.4 3.1 0.15 12.6 3.1 1.3 1 0 0 1 1 1 0 Extracellular mutant protein 11 Ada3 PF10198.9 KSA02195.1 - 2e-41 141.3 7.9 2e-41 141.3 7.9 2.1 2 1 0 2 2 2 1 Histone acetyltransferases subunit 3 TraI_2 PF07514.11 KSA02195.1 - 0.14 11.1 0.4 0.35 9.8 0.4 1.6 1 0 0 1 1 1 0 Putative helicase Peptidase_M16 PF00675.20 KSA02196.1 - 6e-48 162.6 0.2 1.7e-47 161.1 0.1 1.8 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KSA02196.1 - 2.5e-30 105.8 0.0 1.7e-29 103.2 0.0 2.1 2 0 0 2 2 2 1 Peptidase M16 inactive domain RPA_interact_M PF14767.6 KSA02196.1 - 0.051 14.2 0.2 0.11 13.0 0.2 1.6 1 0 0 1 1 1 0 Replication protein A interacting middle DUF725 PF05267.12 KSA02196.1 - 0.13 12.2 0.5 0.27 11.2 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF725) DUF5394 PF17372.2 KSA02196.1 - 0.28 10.7 4.2 6.4 6.3 1.6 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5394) LicD PF04991.13 KSA02197.1 - 1.2e-23 84.5 4.4 5.8e-22 79.0 1.3 4.9 3 2 3 6 6 6 2 LicD family DDE_1 PF03184.19 KSA02198.1 - 3.8e-12 46.2 0.4 1.9e-11 43.9 0.0 2.3 2 0 0 2 2 2 1 DDE superfamily endonuclease RNase_J_C PF17770.1 KSA02198.1 - 0.25 12.4 1.7 1.3 10.1 0.1 3.0 2 0 0 2 2 2 0 Ribonuclease J C-terminal domain PRELI PF04707.14 KSA02199.1 - 3.4e-48 163.4 1.3 4.3e-48 163.1 1.3 1.1 1 0 0 1 1 1 1 PRELI-like family Pico_P2B PF01552.17 KSA02199.1 - 0.1 12.8 0.1 1 9.5 0.0 2.3 2 0 0 2 2 2 0 Picornavirus 2B protein FAM131 PF15010.6 KSA02200.1 - 0.0055 16.6 2.5 0.0079 16.1 2.5 1.3 1 0 0 1 1 1 1 Putative cell signalling CheZ PF04344.13 KSA02200.1 - 0.2 11.6 7.2 0.033 14.1 2.2 2.1 2 1 0 2 2 2 0 Chemotaxis phosphatase, CheZ SKA2 PF16740.5 KSA02200.1 - 0.24 11.2 7.4 0.068 13.0 3.7 2.0 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 Goodbye PF17109.5 KSA02200.1 - 2.8 8.4 9.6 4.2 7.8 0.6 2.9 2 1 2 4 4 4 0 fungal STAND N-terminal Goodbye domain ubiquitin PF00240.23 KSA02203.1 - 3.4e-34 116.4 0.6 7.5e-34 115.3 0.6 1.6 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.19 KSA02203.1 - 5e-26 90.6 2.2 1.2e-25 89.3 2.2 1.7 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.8 KSA02203.1 - 2.1e-16 59.5 0.8 4.7e-16 58.4 0.7 1.6 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KSA02203.1 - 2.2e-05 24.8 0.5 0.00012 22.4 0.1 2.2 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 KSA02203.1 - 0.0013 18.8 0.5 0.0028 17.8 0.5 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 KSA02203.1 - 0.0034 17.7 0.4 0.0076 16.6 0.0 1.7 1 1 1 2 2 2 1 Ubiquitin-like domain TBK1_ULD PF18396.1 KSA02203.1 - 0.0053 16.7 0.0 0.0079 16.1 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 KSA02203.1 - 0.011 16.3 0.6 0.015 15.8 0.6 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 KSA02203.1 - 0.018 15.1 1.0 5.7 7.1 0.2 2.4 2 0 0 2 2 2 0 Ubiquitin-like domain Sde2_N_Ubi PF13019.6 KSA02203.1 - 0.082 12.7 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Silencing defective 2 N-terminal ubiquitin domain Sec10 PF07393.11 KSA02204.1 - 4.4e-212 706.4 23.5 5.4e-212 706.1 23.5 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 CALCOCO1 PF07888.11 KSA02204.1 - 3.7 6.3 9.0 1.2 8.0 0.7 2.2 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Metallophos PF00149.28 KSA02205.1 - 2.1e-12 48.0 0.7 3.9e-12 47.1 0.7 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase SAS4 PF15460.6 KSA02206.1 - 6.7e-33 112.7 5.9 6.7e-33 112.7 5.9 2.3 2 0 0 2 2 2 1 Something about silencing, SAS, complex subunit 4 HARE-HTH PF05066.13 KSA02206.1 - 0.03 14.7 0.7 33 5.0 0.0 3.3 3 0 0 3 3 3 0 HB1, ASXL, restriction endonuclease HTH domain Nipped-B_C PF12830.7 KSA02207.1 - 2.5e-44 151.5 1.4 2.5e-44 151.5 1.4 3.3 3 0 0 3 3 3 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 KSA02207.1 - 1.4e-16 60.4 6.4 5.1e-14 52.3 3.6 3.1 1 1 1 2 2 2 2 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.7 KSA02207.1 - 0.00013 22.0 1.7 0.00013 22.0 1.7 4.6 4 1 2 6 6 6 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KSA02207.1 - 0.0095 16.1 0.0 14 6.3 0.0 3.8 3 0 0 3 3 3 2 HEAT repeat Glyco_transf_41 PF13844.6 KSA02208.1 - 0.034 12.6 0.1 0.038 12.4 0.1 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 41 CybS PF05328.12 KSA02209.1 - 1.8e-51 173.3 0.0 2.1e-51 173.1 0.0 1.1 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit PXA PF02194.15 KSA02211.1 - 1.6e-23 83.6 5.0 3.4e-23 82.6 5.0 1.5 1 0 0 1 1 1 1 PXA domain BPL_LplA_LipB PF03099.19 KSA02212.1 - 7e-10 38.9 0.0 1.2e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Com_YlbF PF06133.11 KSA02212.1 - 1 10.0 7.0 8.1 7.1 0.0 2.8 3 0 0 3 3 3 0 Control of competence regulator ComK, YlbF/YmcA DASH_Spc19 PF08287.11 KSA02213.1 - 1.6e-44 151.6 12.1 2.2e-44 151.1 12.1 1.2 1 0 0 1 1 1 1 Spc19 Phage_lysis PF03245.13 KSA02213.1 - 0.16 12.1 3.2 0.21 11.7 2.8 1.5 1 1 0 1 1 1 0 Bacteriophage Rz lysis protein Exonuc_VII_L PF02601.15 KSA02213.1 - 0.2 11.2 4.7 0.26 10.8 4.7 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Baculo_PEP_C PF04513.12 KSA02213.1 - 3.4 7.7 9.9 3.4 7.7 6.9 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus XhlA PF10779.9 KSA02213.1 - 5.8 7.2 9.2 1.2 9.3 2.4 2.8 2 1 1 3 3 3 0 Haemolysin XhlA FHA PF00498.26 KSA02214.1 - 1e-15 57.9 0.1 4.8e-15 55.7 0.0 2.3 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 KSA02214.1 - 0.0017 18.6 0.0 0.0053 17.1 0.0 1.8 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain PDZ_1 PF12812.7 KSA02214.1 - 0.038 14.0 0.3 0.12 12.4 0.3 1.9 1 0 0 1 1 1 0 PDZ-like domain CENP-O PF09496.10 KSA02214.1 - 0.1 12.6 4.1 0.2 11.6 4.1 1.5 1 0 0 1 1 1 0 Cenp-O kinetochore centromere component Exonuc_VII_L PF02601.15 KSA02214.1 - 0.26 10.8 7.8 0.5 9.9 7.8 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit DASH_Dad4 PF08650.10 KSA02214.1 - 0.28 11.2 6.5 0.33 10.9 0.9 3.1 2 0 0 2 2 2 0 DASH complex subunit Dad4 DUF4407 PF14362.6 KSA02214.1 - 1.1 8.5 10.1 2 7.7 10.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GLE1 PF07817.13 KSA02214.1 - 1.6 7.8 8.5 0.1 11.8 2.7 1.9 2 0 0 2 2 2 0 GLE1-like protein YlqD PF11068.8 KSA02214.1 - 1.7 9.1 12.5 3.4 8.1 11.4 2.1 1 1 0 1 1 1 0 YlqD protein Syntaxin-6_N PF09177.11 KSA02214.1 - 2.4 8.8 14.0 12 6.6 0.1 3.6 3 0 0 3 3 3 0 Syntaxin 6, N-terminal DUF2203 PF09969.9 KSA02214.1 - 3.7 8.3 9.6 3.5 8.4 0.8 2.8 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Peptidase_S49_N PF08496.10 KSA02214.1 - 4.1 7.5 10.1 18 5.3 10.1 2.1 1 1 0 1 1 1 0 Peptidase family S49 N-terminal Coq4 PF05019.13 KSA02215.1 - 2.4e-95 318.1 0.0 2.8e-95 317.8 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 GyrI-like PF06445.15 KSA02215.1 - 0.031 14.6 0.1 0.14 12.5 0.0 2.0 2 0 0 2 2 2 0 GyrI-like small molecule binding domain DUF4112 PF13430.6 KSA02216.1 - 2e-11 44.1 0.2 2.7e-11 43.7 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) DUF2524 PF10732.9 KSA02217.1 - 0.0039 17.5 1.6 0.0055 17.0 1.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2524) DUF3545 PF12065.8 KSA02217.1 - 0.055 13.5 2.7 0.1 12.7 2.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3545) Alpha_adaptinC2 PF02883.20 KSA02218.1 - 8.7e-21 74.3 3.2 8.7e-21 74.3 3.2 3.2 3 1 0 3 3 3 1 Adaptin C-terminal domain GAT PF03127.14 KSA02218.1 - 2.6e-18 66.1 1.2 2.6e-18 66.1 1.2 2.2 2 0 0 2 2 2 1 GAT domain GGA_N-GAT PF18308.1 KSA02218.1 - 1.5e-06 27.7 0.2 6.4e-06 25.7 0.1 2.2 2 0 0 2 2 2 1 GGA N-GAT domain GLTP PF08718.11 KSA02218.1 - 0.054 13.8 0.3 0.12 12.7 0.3 1.5 1 0 0 1 1 1 0 Glycolipid transfer protein (GLTP) Sec20 PF03908.13 KSA02218.1 - 3.6 7.6 5.9 0.6 10.1 0.5 2.6 3 0 0 3 3 3 0 Sec20 Fasciclin PF02469.22 KSA02219.1 - 8.7e-07 29.2 1.7 8.8e-07 29.2 0.1 1.7 2 0 0 2 2 2 1 Fasciclin domain Aminotran_5 PF00266.19 KSA02219.1 - 0.02 13.8 0.5 0.039 12.9 0.3 1.5 2 0 0 2 2 2 0 Aminotransferase class-V SPC12 PF06645.13 KSA02219.1 - 0.15 12.2 0.1 0.24 11.5 0.1 1.3 1 0 0 1 1 1 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Recep_L_domain PF01030.24 KSA02220.1 - 4e-07 30.1 9.4 0.00088 19.4 0.1 3.9 1 1 2 4 4 4 4 Receptor L domain RAP1 PF07218.11 KSA02220.1 - 2.3 6.4 26.7 4.5 5.4 26.7 1.4 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PI3K_1B_p101 PF10486.9 KSA02220.1 - 3.9 5.1 9.4 4.8 4.8 9.4 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit GATase_2 PF00310.21 KSA02221.1 - 2e-177 590.2 0.0 2.8e-177 589.6 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 KSA02221.1 - 2.3e-151 504.1 0.0 5.2e-151 503.0 0.0 1.6 2 0 0 2 2 2 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 KSA02221.1 - 1e-111 372.9 0.1 4.8e-111 370.7 0.1 1.9 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 KSA02221.1 - 2.1e-83 278.6 4.6 3.4e-83 277.9 4.6 1.4 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.6 KSA02221.1 - 2e-21 75.9 0.1 4.9e-21 74.6 0.1 1.6 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.14 KSA02221.1 - 5.1e-20 71.9 0.1 1.1e-18 67.5 0.1 2.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KSA02221.1 - 3.2e-10 40.4 1.4 1.5e-05 25.5 0.0 4.6 5 1 0 5 5 4 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KSA02221.1 - 3.2e-08 33.7 0.0 1.3e-07 31.7 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KSA02221.1 - 1.5e-05 24.5 0.0 2.6e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase HI0933_like PF03486.14 KSA02221.1 - 8.9e-05 21.4 2.0 0.00012 20.9 0.1 2.2 3 0 0 3 3 3 1 HI0933-like protein FAD_oxidored PF12831.7 KSA02221.1 - 0.00061 19.3 0.0 0.0012 18.3 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 KSA02221.1 - 0.00062 20.2 0.4 2 8.9 0.0 3.7 3 0 0 3 3 3 1 Putative NAD(P)-binding Pyr_redox_3 PF13738.6 KSA02221.1 - 0.001 18.4 0.4 0.34 10.1 0.0 2.8 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KSA02221.1 - 0.001 18.3 0.3 0.0062 15.8 0.0 2.4 3 0 0 3 3 3 1 Thi4 family NAD_Gly3P_dh_N PF01210.23 KSA02221.1 - 0.0014 18.6 0.0 0.0037 17.2 0.0 1.7 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_binding_2 PF00890.24 KSA02221.1 - 0.0015 17.7 0.0 0.003 16.7 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 KSA02221.1 - 0.0056 16.0 0.0 0.012 14.9 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain 2-Hacid_dh_C PF02826.19 KSA02221.1 - 0.013 14.9 0.0 0.4 10.0 0.0 2.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.22 KSA02221.1 - 0.018 14.1 0.4 0.073 12.1 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A DAO PF01266.24 KSA02221.1 - 0.03 13.9 0.0 0.03 13.9 0.0 2.8 4 0 0 4 4 2 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KSA02221.1 - 0.041 13.2 0.0 1.7 7.9 0.0 2.5 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 KSA02221.1 - 0.11 11.6 0.1 0.25 10.4 0.1 1.6 1 0 0 1 1 1 0 Lycopene cyclase protein B PF02216.16 KSA02221.1 - 0.19 11.8 0.4 0.49 10.4 0.4 1.7 1 0 0 1 1 1 0 B domain AdoHcyase_NAD PF00670.21 KSA02221.1 - 2.2 8.3 5.4 15 5.6 0.3 3.3 2 1 0 3 3 3 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain RNase_PH PF01138.21 KSA02222.1 - 1.3e-22 80.7 0.1 3.6e-22 79.3 0.1 1.7 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 UCH PF00443.29 KSA02223.1 - 4.1e-73 246.1 0.0 1.3e-71 241.1 0.0 3.2 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KSA02223.1 - 7.1e-09 35.7 13.5 2.7e-05 23.9 0.1 3.3 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase RNase_3_N PF18497.1 KSA02223.1 - 0.17 12.1 3.0 2.8 8.2 0.2 3.1 2 0 0 2 2 2 0 Ribonuclease III N-terminal domain Beach PF02138.18 KSA02224.1 - 2.7e-118 394.4 0.4 7.7e-118 392.9 0.4 1.9 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 KSA02224.1 - 2.4e-09 37.2 0.0 7.2e-09 35.7 0.0 1.9 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.32 KSA02224.1 - 0.00035 21.3 1.4 1.6 9.7 0.1 3.5 2 0 0 2 2 2 2 WD domain, G-beta repeat TPT PF03151.16 KSA02225.1 - 7.9e-28 97.6 15.9 8.9e-16 58.1 9.5 3.2 2 1 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.20 KSA02225.1 - 0.00016 21.9 14.8 0.00016 21.9 14.8 4.2 4 1 0 4 4 4 1 EamA-like transporter family DUF2012 PF09430.10 KSA02226.1 - 3.5e-07 30.4 0.1 5.2e-07 29.8 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) SOP4 PF17081.5 KSA02226.1 - 0.00019 21.0 1.7 0.0028 17.2 1.4 2.4 1 1 1 2 2 2 1 Suppressor of PMA 1-7 protein MFS_1 PF07690.16 KSA02227.1 - 2.2e-19 69.6 48.3 1.5e-17 63.6 39.5 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Ribosomal_S11 PF00411.19 KSA02229.1 - 1.1e-46 157.7 1.3 1.4e-46 157.4 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 Ribosomal_L18p PF00861.22 KSA02229.1 - 0.032 14.6 0.1 0.046 14.1 0.1 1.2 1 0 0 1 1 1 0 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast Ribosomal_S8 PF00410.19 KSA02230.1 - 6.1e-24 84.4 0.0 8e-24 84.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 PRA1 PF03208.19 KSA02231.1 - 3.9e-39 133.5 0.4 4.5e-39 133.3 0.4 1.0 1 0 0 1 1 1 1 PRA1 family protein DUF2207 PF09972.9 KSA02231.1 - 0.11 11.2 0.6 0.11 11.2 0.6 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Peptidase_M1 PF01433.20 KSA02232.1 - 7.1e-49 166.3 0.4 7.1e-49 166.3 0.4 1.4 2 0 0 2 2 2 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 KSA02232.1 - 1.1e-36 125.3 0.4 1.3e-35 121.9 0.1 2.4 2 0 0 2 2 2 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M48 PF01435.18 KSA02232.1 - 0.041 13.7 0.0 0.071 12.9 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M48 Peptidase_M61 PF05299.12 KSA02232.1 - 2.5 8.5 5.2 12 6.3 2.6 2.8 2 1 0 2 2 2 0 M61 glycyl aminopeptidase SF1-HH PF16275.5 KSA02233.1 - 9.5e-37 125.8 0.6 2.3e-36 124.6 0.6 1.7 1 0 0 1 1 1 1 Splicing factor 1 helix-hairpin domain KH_1 PF00013.29 KSA02233.1 - 2.3e-06 27.4 0.2 2e-05 24.3 0.0 2.5 2 1 0 2 2 2 1 KH domain zf-CCHC PF00098.23 KSA02233.1 - 4.2e-05 23.4 0.3 6.8e-05 22.8 0.3 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 KSA02233.1 - 0.0033 17.2 1.5 0.0067 16.2 1.5 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 KSA02233.1 - 0.15 11.8 1.1 0.37 10.6 1.1 1.6 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger MTS PF05175.14 KSA02234.1 - 0.00043 19.9 0.0 0.00067 19.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain GFRP PF06399.13 KSA02234.1 - 0.064 13.1 0.0 0.31 11.0 0.0 2.0 2 0 0 2 2 2 0 GTP cyclohydrolase I feedback regulatory protein (GFRP) Methyltransf_12 PF08242.12 KSA02234.1 - 0.071 13.9 0.0 0.11 13.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain ubiquitin PF00240.23 KSA02235.1 - 3.2e-22 78.0 0.0 3.7e-22 77.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KSA02235.1 - 3.6e-14 52.3 0.1 4e-14 52.2 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 KSA02235.1 - 0.005 16.7 0.0 0.0059 16.5 0.0 1.1 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain TUG-UBL1 PF11470.8 KSA02235.1 - 0.13 12.5 0.0 0.15 12.3 0.0 1.2 1 0 0 1 1 1 0 TUG ubiquitin-like domain DUF2407 PF10302.9 KSA02235.1 - 0.14 12.7 0.0 0.2 12.2 0.0 1.3 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 KSA02235.1 - 0.19 11.8 0.2 10 6.2 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin-like domain TPR_14 PF13428.6 KSA02236.1 - 7.8e-11 41.9 0.1 1 10.4 0.0 7.2 6 2 2 8 8 8 3 Tetratricopeptide repeat Suf PF05843.14 KSA02236.1 - 5e-07 30.0 35.8 0.0011 19.1 2.8 8.0 1 1 4 5 5 5 2 Suppressor of forked protein (Suf) HAT PF02184.16 KSA02236.1 - 1e-05 25.4 46.0 0.00032 20.6 0.7 10.0 10 0 0 10 10 10 2 HAT (Half-A-TPR) repeat TPR_2 PF07719.17 KSA02236.1 - 2.2e-05 24.2 1.3 6 7.2 0.4 7.0 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_12 PF13424.6 KSA02236.1 - 0.00055 20.2 1.2 15 6.0 0.1 5.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 KSA02236.1 - 0.00076 19.9 0.0 0.11 13.1 0.0 3.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 KSA02236.1 - 0.024 14.8 1.4 89 3.7 0.0 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat U3_assoc_6 PF08640.11 KSA02236.1 - 0.14 12.2 0.2 0.14 12.2 0.2 6.9 6 2 2 8 8 8 0 U3 small nucleolar RNA-associated protein 6 TPR_6 PF13174.6 KSA02236.1 - 0.68 10.7 3.7 20 6.1 0.5 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat PA PF02225.22 KSA02237.1 - 4.3e-09 36.3 0.0 9e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 PA domain Peptidase_M28 PF04389.17 KSA02237.1 - 9.7e-07 28.7 0.0 2.8e-06 27.2 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M28 TFR_dimer PF04253.15 KSA02237.1 - 8.9e-05 22.6 0.0 0.00026 21.1 0.0 1.8 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Rad21_Rec8_N PF04825.13 KSA02238.1 - 1.7e-20 73.2 0.1 4.9e-20 71.7 0.1 1.7 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 KSA02238.1 - 0.0021 17.3 0.0 0.0057 15.9 0.0 1.6 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein EFG_II PF14492.6 KSA02238.1 - 0.32 11.1 1.4 4 7.6 0.3 2.7 2 0 0 2 2 2 0 Elongation Factor G, domain II Nop PF01798.18 KSA02238.1 - 0.56 9.6 5.9 1.2 8.6 2.3 2.5 2 0 0 2 2 2 0 snoRNA binding domain, fibrillarin DUF5398 PF17376.2 KSA02238.1 - 3.7 8.2 6.4 53 4.5 0.1 3.7 4 0 0 4 4 4 0 Family of unknown function (DUF5398) Pil1 PF13805.6 KSA02239.1 - 1.3e-124 414.9 0.4 1.6e-124 414.7 0.4 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 Nop10p PF04135.12 KSA02239.1 - 0.63 10.1 4.3 4.3 7.5 0.2 2.4 2 0 0 2 2 2 0 Nucleolar RNA-binding protein, Nop10p family Hat1_N PF10394.9 KSA02240.1 - 4.4e-44 150.5 0.0 8.6e-44 149.6 0.0 1.5 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Amidase PF01425.21 KSA02241.1 - 8.9e-89 298.5 0.0 1.4e-88 297.9 0.0 1.2 1 0 0 1 1 1 1 Amidase CT_A_B PF02626.15 KSA02241.1 - 6.7e-88 294.7 0.0 1.9e-87 293.2 0.0 1.9 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain A and B CPSase_L_D2 PF02786.17 KSA02241.1 - 1.7e-64 217.2 0.1 3.8e-64 216.1 0.1 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CT_C_D PF02682.16 KSA02241.1 - 3.7e-47 160.7 0.0 7.5e-47 159.7 0.0 1.5 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain C and D Biotin_carb_N PF00289.22 KSA02241.1 - 3.3e-39 133.8 0.0 1.4e-38 131.9 0.0 2.2 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KSA02241.1 - 8e-33 112.8 0.0 1.6e-32 111.8 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 KSA02241.1 - 3.1e-16 59.0 4.5 1e-15 57.3 4.5 2.0 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 KSA02241.1 - 3.5e-12 46.3 0.4 8.8e-12 45.0 0.1 1.8 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KSA02241.1 - 5.6e-06 26.0 0.7 2.8e-05 23.8 0.1 2.2 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_3 PF02655.14 KSA02241.1 - 6.2e-05 23.1 0.0 0.00014 22.0 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_5 PF13549.6 KSA02241.1 - 0.025 14.0 0.1 0.053 13.0 0.1 1.5 1 0 0 1 1 1 0 ATP-grasp domain Methyltransf_15 PF09445.10 KSA02241.1 - 0.064 12.8 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Biotin_lipoyl_2 PF13533.6 KSA02241.1 - 0.093 12.6 4.7 4.4 7.2 0.1 2.8 1 1 1 2 2 2 0 Biotin-lipoyl like ATPgrasp_Ter PF15632.6 KSA02241.1 - 0.17 11.6 0.0 0.36 10.6 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon Prot_ATP_ID_OB PF16450.5 KSA02241.1 - 0.19 11.7 2.4 0.29 11.1 1.3 2.0 2 0 0 2 2 2 0 Proteasomal ATPase OB C-terminal domain SSF PF00474.17 KSA02242.1 - 2.4e-16 59.6 26.8 4.1e-16 58.9 26.8 1.4 1 0 0 1 1 1 1 Sodium:solute symporter family Peptidase_A21 PF03566.13 KSA02242.1 - 0.5 8.6 2.4 0.79 7.9 2.4 1.2 1 0 0 1 1 1 0 Peptidase family A21 EAP30 PF04157.16 KSA02243.1 - 6.5e-32 110.7 0.0 1e-31 110.1 0.0 1.3 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36-NZF-N PF16988.5 KSA02243.1 - 4e-16 58.2 0.9 4e-16 58.2 0.9 2.7 2 1 0 2 2 2 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain Vps36_ESCRT-II PF11605.8 KSA02243.1 - 1.1e-15 57.5 0.1 3.1e-15 56.1 0.1 1.9 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 zf-RanBP PF00641.18 KSA02243.1 - 0.00015 21.0 6.7 0.004 16.4 0.9 2.6 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others DZR PF12773.7 KSA02243.1 - 0.0064 16.5 3.5 0.0083 16.1 0.4 2.1 1 1 1 2 2 2 2 Double zinc ribbon GRAM PF02893.20 KSA02243.1 - 0.0085 16.0 0.1 0.045 13.6 0.0 2.3 2 0 0 2 2 2 1 GRAM domain bPH_3 PF14470.6 KSA02243.1 - 0.018 15.4 0.1 0.044 14.2 0.1 1.7 1 0 0 1 1 1 0 Bacterial PH domain zinc_ribbon_15 PF17032.5 KSA02243.1 - 0.12 13.2 5.1 0.29 11.9 4.8 1.9 1 1 0 1 1 1 0 zinc-ribbon family DUF35_N PF12172.8 KSA02243.1 - 0.13 12.2 0.2 0.13 12.2 0.2 1.9 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zf-Sec23_Sec24 PF04810.15 KSA02243.1 - 0.58 10.3 5.2 2.2 8.4 0.2 2.6 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger YebO PF13974.6 KSA02243.1 - 0.64 10.1 2.9 5.6 7.1 0.5 3.3 3 0 0 3 3 3 0 YebO-like protein Mo25 PF08569.11 KSA02244.1 - 5.6e-117 390.8 16.6 6.3e-117 390.6 16.6 1.0 1 0 0 1 1 1 1 Mo25-like Aminotran_4 PF01063.19 KSA02245.1 - 8.9e-42 143.4 0.0 1.1e-41 143.2 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Glyco_hydro_47 PF01532.20 KSA02246.1 - 4.2e-114 382.0 0.5 5.2e-114 381.7 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Phosphodiest PF01663.22 KSA02247.1 - 9e-14 51.8 0.6 1.4e-13 51.2 0.6 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KSA02247.1 - 0.00038 20.0 0.4 0.00058 19.4 0.4 1.3 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 KSA02247.1 - 0.00063 19.2 0.2 0.0012 18.2 0.2 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily DUF2839 PF10999.8 KSA02247.1 - 0.0027 18.0 0.5 0.81 10.1 0.1 3.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2839) MCM6_C PF18263.1 KSA02247.1 - 0.16 12.2 0.0 0.48 10.7 0.0 1.7 1 0 0 1 1 1 0 MCM6 C-terminal winged-helix domain Pkinase PF00069.25 KSA02249.1 - 2.8e-67 226.9 0.0 4.5e-67 226.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KSA02249.1 - 9.7e-30 103.7 0.0 1.5e-29 103.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 KSA02249.1 - 1.5e-13 51.2 2.5 2.7e-13 50.4 0.9 2.4 2 0 0 2 2 2 1 Protein kinase C terminal domain C2 PF00168.30 KSA02249.1 - 1.1e-10 41.7 0.0 5.2e-06 26.7 0.0 2.7 2 0 0 2 2 2 2 C2 domain Kinase-like PF14531.6 KSA02249.1 - 3.8e-08 33.0 0.0 1.3e-07 31.3 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KSA02249.1 - 0.00078 18.5 0.1 0.0031 16.5 0.0 2.0 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 KSA02249.1 - 0.079 12.9 0.1 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 KSA02249.1 - 0.098 12.3 2.0 1.9 8.1 0.0 2.7 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KSA02249.1 - 0.11 11.8 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L28 PF00830.19 KSA02250.1 - 1.2e-10 41.4 6.4 4.3e-10 39.6 5.4 2.3 1 1 1 2 2 2 1 Ribosomal L28 family Ribosomal_L36e PF01158.18 KSA02251.1 - 9e-38 128.4 7.3 1e-37 128.3 7.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e LemA PF04011.12 KSA02251.1 - 0.0082 16.0 0.2 0.01 15.7 0.2 1.2 1 0 0 1 1 1 1 LemA family DUF2207 PF09972.9 KSA02251.1 - 0.14 10.9 0.1 0.14 10.9 0.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) MTCP1 PF08991.10 KSA02253.1 - 1.5e-27 95.6 15.1 1.8e-27 95.3 15.1 1.1 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type CHCH PF06747.13 KSA02253.1 - 0.00069 19.7 4.0 0.00069 19.7 4.0 2.3 1 1 1 2 2 2 1 CHCH domain Type_III_YscG PF09477.10 KSA02253.1 - 0.12 12.4 0.0 0.13 12.3 0.0 1.1 1 0 0 1 1 1 0 Bacterial type II secretion system chaperone protein (type_III_yscG) DUF1640 PF07798.11 KSA02254.1 - 2.5e-34 118.8 5.3 5.6e-34 117.7 5.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) FAST_1 PF06743.15 KSA02254.1 - 0.041 13.8 0.3 3.6 7.6 0.0 3.4 1 1 2 3 3 3 0 FAST kinase-like protein, subdomain 1 POP1 PF06978.11 KSA02254.1 - 7.3 6.5 10.4 14 5.6 5.1 2.3 2 0 0 2 2 2 0 Ribonucleases P/MRP protein subunit POP1 Asp PF00026.23 KSA02256.1 - 4.2e-51 174.2 7.7 6.7e-51 173.6 7.7 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KSA02256.1 - 6e-08 33.1 7.3 2.8e-07 30.9 0.7 3.0 3 1 0 3 3 3 1 Xylanase inhibitor N-terminal AAA PF00004.29 KSA02257.1 - 8.6e-97 320.7 0.1 2e-48 164.2 0.0 3.0 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KSA02257.1 - 4.2e-23 80.9 0.1 1.3e-10 40.9 0.0 2.8 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 KSA02257.1 - 1.2e-15 57.6 0.1 2.2e-08 34.0 0.0 2.8 3 0 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KSA02257.1 - 7.1e-13 49.3 3.1 0.00012 22.5 0.0 4.8 3 2 0 3 3 3 2 AAA ATPase domain AAA_2 PF07724.14 KSA02257.1 - 1.2e-12 48.3 0.0 0.00012 22.2 0.0 3.1 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KSA02257.1 - 1.5e-11 44.5 0.5 2.1e-05 24.5 0.0 4.0 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KSA02257.1 - 2.3e-10 40.9 0.8 0.013 15.8 0.0 5.0 3 2 1 4 4 3 2 AAA domain AAA_33 PF13671.6 KSA02257.1 - 3.3e-09 37.0 0.0 0.0014 18.8 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KSA02257.1 - 3.5e-09 37.3 0.0 0.00017 22.1 0.0 3.3 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 KSA02257.1 - 1.4e-08 34.4 0.0 0.00055 19.2 0.0 2.4 2 0 0 2 2 2 2 TIP49 P-loop domain RNA_helicase PF00910.22 KSA02257.1 - 1.7e-08 34.8 0.0 0.0011 19.3 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_14 PF13173.6 KSA02257.1 - 1.9e-08 34.4 0.0 0.0056 16.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.27 KSA02257.1 - 2e-08 34.8 2.7 0.0054 17.2 0.0 3.9 3 2 0 3 3 3 2 ABC transporter Mg_chelatase PF01078.21 KSA02257.1 - 3.8e-07 29.7 0.1 0.025 13.9 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 KSA02257.1 - 6.4e-07 29.8 0.0 0.011 16.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 KSA02257.1 - 8.3e-07 28.5 0.0 0.035 13.4 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin NB-ARC PF00931.22 KSA02257.1 - 1e-06 28.2 0.0 1.1 8.3 0.0 3.7 3 0 0 3 3 3 2 NB-ARC domain IstB_IS21 PF01695.17 KSA02257.1 - 1.7e-06 27.9 0.4 0.078 12.7 0.0 2.9 3 0 0 3 3 2 2 IstB-like ATP binding protein Rad17 PF03215.15 KSA02257.1 - 3.4e-06 27.1 0.0 0.022 14.7 0.0 2.5 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_3 PF07726.11 KSA02257.1 - 3.9e-06 26.7 0.0 0.051 13.4 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KSA02257.1 - 5.4e-06 26.0 0.0 0.027 14.0 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region Vps4_C PF09336.10 KSA02257.1 - 1.1e-05 25.3 0.0 0.024 14.7 0.0 3.2 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain TsaE PF02367.17 KSA02257.1 - 2.1e-05 24.5 0.0 0.13 12.2 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 KSA02257.1 - 2.4e-05 24.0 3.3 0.18 11.4 0.0 3.9 4 1 0 4 4 3 2 AAA domain AAA_17 PF13207.6 KSA02257.1 - 2.6e-05 24.6 4.9 0.0076 16.7 0.0 3.8 4 1 0 4 4 3 1 AAA domain NACHT PF05729.12 KSA02257.1 - 2.6e-05 24.2 0.0 0.26 11.2 0.0 3.2 3 0 0 3 3 3 2 NACHT domain Cytidylate_kin2 PF13189.6 KSA02257.1 - 2.7e-05 24.4 4.9 0.00029 21.0 0.0 3.2 4 0 0 4 4 2 1 Cytidylate kinase-like family DUF815 PF05673.13 KSA02257.1 - 3.2e-05 23.2 0.0 0.046 12.9 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_24 PF13479.6 KSA02257.1 - 3.3e-05 23.7 1.1 0.075 12.7 0.0 2.8 3 0 0 3 3 2 2 AAA domain SKI PF01202.22 KSA02257.1 - 7.8e-05 22.9 0.2 0.11 12.7 0.0 3.1 3 0 0 3 3 2 1 Shikimate kinase ATPase PF06745.13 KSA02257.1 - 8.8e-05 22.0 0.3 0.73 9.1 0.0 3.5 3 0 0 3 3 3 2 KaiC ATPase_2 PF01637.18 KSA02257.1 - 0.00017 21.6 3.3 0.86 9.5 0.0 4.3 3 2 1 4 4 4 2 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 KSA02257.1 - 0.00031 20.5 0.0 0.37 10.5 0.0 3.0 3 0 0 3 3 3 1 Sigma-54 interaction domain Viral_helicase1 PF01443.18 KSA02257.1 - 0.00042 20.1 0.0 0.51 10.0 0.0 2.8 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Sigma54_activ_2 PF14532.6 KSA02257.1 - 0.00058 20.0 0.0 1.5 8.9 0.0 2.7 2 0 0 2 2 2 2 Sigma-54 interaction domain Parvo_NS1 PF01057.17 KSA02257.1 - 0.00066 18.9 0.1 0.77 8.8 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_19 PF13245.6 KSA02257.1 - 0.0018 18.6 0.0 0.65 10.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 KSA02257.1 - 0.0036 17.2 0.0 1.7 8.5 0.0 2.8 2 0 0 2 2 2 1 NTPase CPT PF07931.12 KSA02257.1 - 0.004 17.0 0.0 0.096 12.5 0.0 2.4 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein PduV-EutP PF10662.9 KSA02257.1 - 0.0048 16.7 0.0 2 8.1 0.0 2.5 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation PhoH PF02562.16 KSA02257.1 - 0.0065 15.9 0.3 2.4 7.6 0.0 2.8 3 0 0 3 3 2 1 PhoH-like protein SRPRB PF09439.10 KSA02257.1 - 0.009 15.5 0.0 5.1 6.5 0.0 3.4 4 0 0 4 4 3 0 Signal recognition particle receptor beta subunit Bac_DnaA PF00308.18 KSA02257.1 - 0.0098 15.7 0.0 0.69 9.7 0.0 3.2 3 1 0 3 3 2 1 Bacterial dnaA protein Cytidylate_kin PF02224.18 KSA02257.1 - 0.01 15.6 2.2 0.36 10.5 0.0 3.2 4 0 0 4 4 2 0 Cytidylate kinase RsgA_GTPase PF03193.16 KSA02257.1 - 0.016 15.1 0.0 0.32 10.9 0.0 2.6 2 0 0 2 2 2 0 RsgA GTPase AAA_30 PF13604.6 KSA02257.1 - 0.019 14.7 0.6 7.8 6.2 0.0 3.3 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 KSA02257.1 - 0.021 14.9 0.1 0.89 9.7 0.0 3.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase FeoB_N PF02421.18 KSA02257.1 - 0.021 14.3 0.1 0.9 9.0 0.0 2.8 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_29 PF13555.6 KSA02257.1 - 0.029 14.1 0.0 1.6 8.5 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain TniB PF05621.11 KSA02257.1 - 0.033 13.6 0.0 11 5.4 0.0 3.1 3 0 0 3 3 3 0 Bacterial TniB protein ADK PF00406.22 KSA02257.1 - 0.042 13.9 0.0 3.4 7.8 0.0 2.6 2 0 0 2 2 2 0 Adenylate kinase T2SSE PF00437.20 KSA02257.1 - 0.057 12.5 0.0 1.4 7.9 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_23 PF13476.6 KSA02257.1 - 0.21 12.1 0.0 0.21 12.1 0.0 4.4 4 1 0 4 4 2 0 AAA domain Hydin_ADK PF17213.3 KSA02257.1 - 1.2 9.4 7.7 8.4 6.6 0.0 3.3 3 0 0 3 3 3 0 Hydin Adenylate kinase-like domain AAA_11 PF13086.6 KSA02257.1 - 1.4 8.7 19.5 1.6 8.4 0.0 3.6 3 1 0 3 3 2 0 AAA domain EF-G-binding_N PF07299.11 KSA02257.1 - 9.7 6.8 9.6 20 5.8 0.6 3.6 4 0 0 4 4 2 0 Elongation factor G-binding protein, N-terminal HSP9_HSP12 PF04119.12 KSA02258.1 - 1.9e-26 92.2 5.7 1.9e-26 92.2 5.7 2.5 2 1 0 2 2 2 1 Heat shock protein 9/12 Apolipoprotein PF01442.18 KSA02258.1 - 0.0042 17.0 1.6 0.0074 16.2 1.6 1.5 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Exonuc_V_gamma PF04257.14 KSA02258.1 - 0.015 13.5 0.1 0.019 13.2 0.1 1.0 1 0 0 1 1 1 0 Exodeoxyribonuclease V, gamma subunit Grg1 PF11034.8 KSA02258.1 - 0.032 14.5 16.9 0.16 12.2 3.5 3.7 1 1 2 3 3 3 0 Glucose-repressible protein Grg1 DUF445 PF04286.12 KSA02258.1 - 0.045 13.5 0.2 0.05 13.4 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Mt_ATP-synt_B PF05405.14 KSA02258.1 - 0.073 12.7 2.9 0.5 10.0 0.4 2.0 1 1 1 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF883 PF05957.13 KSA02258.1 - 0.37 11.4 4.5 1.5 9.5 3.9 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 KSA02258.1 - 1.7 9.2 18.0 3.2e+03 -1.3 18.0 2.9 1 1 0 1 1 1 0 YtxH-like protein RRM_1 PF00076.22 KSA02259.1 - 1.3e-06 28.1 0.6 0.00028 20.7 0.1 2.9 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) bPH_5 PF10882.8 KSA02259.1 - 0.11 12.6 0.3 0.33 11.0 0.0 1.9 2 0 0 2 2 2 0 Bacterial PH domain Lipl32 PF12103.8 KSA02259.1 - 4 7.1 8.8 1.7 8.3 1.1 2.4 2 0 0 2 2 2 0 Surface lipoprotein of Spirochaetales order Dopey_N PF04118.14 KSA02261.1 - 5.9e-109 363.9 7.5 5.9e-109 363.9 7.5 2.7 2 0 0 2 2 2 1 Dopey, N-terminal MRP-S28 PF10213.9 KSA02261.1 - 0.053 14.0 0.4 0.48 10.9 0.1 2.8 2 0 0 2 2 2 0 Mitochondrial ribosomal subunit protein Abhydrolase_2 PF02230.16 KSA02262.1 - 2.8e-60 203.8 0.0 3.5e-60 203.5 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase FSH1 PF03959.13 KSA02262.1 - 5.3e-10 39.3 0.0 2e-09 37.5 0.0 1.9 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Hydrolase_4 PF12146.8 KSA02262.1 - 1.6e-08 34.1 0.0 0.00021 20.6 0.0 3.0 2 1 1 3 3 3 2 Serine aminopeptidase, S33 DLH PF01738.18 KSA02262.1 - 6.2e-07 29.2 0.0 9.3e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 KSA02262.1 - 1.4e-05 25.8 0.0 3.4e-05 24.5 0.0 1.4 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KSA02262.1 - 0.00016 21.2 0.2 0.0066 16.0 0.0 2.6 2 1 1 3 3 3 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KSA02262.1 - 0.001 18.8 1.1 0.5 10.0 0.1 2.9 2 1 1 3 3 3 2 alpha/beta hydrolase fold Lipase_3 PF01764.25 KSA02262.1 - 0.022 14.6 0.0 0.036 13.9 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Cutinase PF01083.22 KSA02262.1 - 0.061 13.3 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Cutinase Dus PF01207.17 KSA02263.1 - 4.4e-74 249.4 0.0 5.9e-74 248.9 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) zf-C2H2 PF00096.26 KSA02264.1 - 6.4e-08 32.6 11.4 0.002 18.5 3.1 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KSA02264.1 - 1.1e-06 28.7 7.5 3.3e-06 27.3 4.0 2.6 2 0 0 2 2 2 1 Zinc-finger double domain Fungal_trans PF04082.18 KSA02264.1 - 3.6e-06 26.2 7.8 1.6e-05 24.1 7.8 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2_4 PF13894.6 KSA02264.1 - 6.3e-05 23.5 11.0 0.021 15.6 2.4 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KSA02264.1 - 4.2 7.2 7.3 0.25 11.1 0.6 2.3 2 0 0 2 2 2 0 zinc-finger C2H2-type Glyco_tran_28_C PF04101.16 KSA02265.1 - 1.1e-20 74.2 0.1 4.6e-20 72.3 0.1 1.9 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain RE_HindVP PF09519.10 KSA02265.1 - 0.038 13.0 0.2 0.052 12.6 0.2 1.1 1 0 0 1 1 1 0 HindVP restriction endonuclease QSregVF PF13652.6 KSA02265.1 - 0.044 13.8 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Putative quorum-sensing-regulated virulence factor FtsL PF04999.13 KSA02265.1 - 0.091 12.8 0.1 0.17 11.9 0.1 1.5 1 0 0 1 1 1 0 Cell division protein FtsL TFIID-18kDa PF02269.16 KSA02266.1 - 1.1e-20 73.5 0.0 1.6e-20 72.9 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.13 KSA02266.1 - 0.0021 18.0 0.1 0.0039 17.2 0.0 1.5 1 1 1 2 2 2 1 Bromodomain associated CENP-S PF15630.6 KSA02266.1 - 0.017 15.5 0.0 0.031 14.6 0.0 1.4 1 0 0 1 1 1 0 CENP-S protein RINGv PF12906.7 KSA02267.1 - 2.1e-15 56.5 9.3 4.3e-15 55.6 9.3 1.5 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 KSA02267.1 - 0.11 12.8 8.1 0.21 11.9 8.1 1.5 1 0 0 1 1 1 0 Ring finger domain FANCL_C PF11793.8 KSA02267.1 - 0.52 10.5 3.6 1.1 9.5 3.6 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain PMT PF02366.18 KSA02268.1 - 6.6e-80 268.2 12.9 1.4e-79 267.1 12.9 1.5 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KSA02268.1 - 9.2e-61 204.9 19.4 9.2e-61 204.9 19.4 2.0 3 0 0 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KSA02268.1 - 4.4e-48 163.6 0.0 9.7e-48 162.5 0.0 1.5 1 0 0 1 1 1 1 MIR domain SRP9-21 PF05486.12 KSA02269.1 - 3.7e-27 94.6 0.8 3.7e-27 94.6 0.8 2.4 2 1 1 3 3 3 1 Signal recognition particle 9 kDa protein (SRP9) Nramp PF01566.18 KSA02270.1 - 4.8e-88 295.5 8.4 5.7e-49 167.0 5.3 2.1 2 0 0 2 2 2 2 Natural resistance-associated macrophage protein Biotin_lipoyl PF00364.22 KSA02271.1 - 7.1e-19 67.4 0.4 1.5e-18 66.4 0.4 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 KSA02271.1 - 2.8e-08 34.0 0.0 1e-07 32.2 0.0 2.0 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 KSA02271.1 - 0.088 12.7 0.0 2.1 8.2 0.0 2.9 3 0 0 3 3 3 0 Biotin-lipoyl like Ndc1_Nup PF09531.10 KSA02271.1 - 0.52 8.9 7.3 0.7 8.5 7.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF3097 PF11296.8 KSA02272.1 - 0.054 12.7 0.1 0.088 12.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3097) AT_hook PF02178.19 KSA02272.1 - 0.15 12.0 26.9 0.53 10.3 3.4 3.8 3 0 0 3 3 3 0 AT hook motif PAT1 PF09770.9 KSA02272.1 - 0.32 9.2 12.4 0.4 8.9 12.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RFX5_DNA_bdg PF14621.6 KSA02272.1 - 1.7 8.4 13.1 1.8 8.3 0.2 3.2 2 1 1 3 3 3 0 RFX5 DNA-binding domain TFIIA PF03153.13 KSA02272.1 - 8.5 6.3 15.7 10 6.0 15.7 1.3 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1765 PF08578.10 KSA02273.1 - 3.2e-41 140.7 9.1 3.2e-41 140.7 9.1 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF1765) AA_permease_C PF13906.6 KSA02273.1 - 0.53 10.4 5.2 0.4 10.8 1.7 2.5 2 0 0 2 2 2 0 C-terminus of AA_permease Seipin PF06775.14 KSA02274.1 - 6.1e-09 36.3 5.2 4.8e-08 33.3 5.2 2.0 1 1 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) zf-H2C2_2 PF13465.6 KSA02275.1 - 0.00026 21.3 11.7 0.054 13.9 0.6 3.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_aberr PF17017.5 KSA02275.1 - 0.0012 19.0 7.3 0.092 12.9 0.4 2.8 3 0 0 3 3 3 2 Aberrant zinc-finger zf-C2H2 PF00096.26 KSA02275.1 - 0.0051 17.2 9.4 0.014 15.8 1.0 4.9 5 0 0 5 5 5 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KSA02275.1 - 0.0089 16.8 5.1 0.036 14.9 0.5 4.8 6 0 0 6 6 6 2 C2H2-type zinc finger PCM1_C PF15717.5 KSA02275.1 - 0.011 14.5 6.4 0.015 14.0 6.4 1.1 1 0 0 1 1 1 0 Pericentriolar material 1 C terminus PAT1 PF09770.9 KSA02275.1 - 4 5.6 19.4 4.7 5.4 19.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 F-box PF00646.33 KSA02276.1 - 2.1e-05 24.2 1.2 0.0032 17.3 0.1 3.8 4 0 0 4 4 4 1 F-box domain F-box_4 PF15966.5 KSA02276.1 - 0.011 15.6 0.1 0.011 15.6 0.1 2.2 2 0 0 2 2 2 0 F-box F-box-like PF12937.7 KSA02276.1 - 0.031 14.2 0.5 0.32 10.9 0.0 2.8 3 0 0 3 3 3 0 F-box-like Transp_cyt_pur PF02133.15 KSA02277.1 - 9.1e-54 182.9 36.3 1.1e-53 182.6 36.3 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin TIC20 PF16166.5 KSA02277.1 - 0.64 9.8 6.2 0.11 12.3 2.0 1.9 2 0 0 2 2 2 0 Chloroplast import apparatus Tic20-like Glyco_hydro_63 PF03200.16 KSA02278.1 - 2.9e-09 36.2 5.4 1.5e-06 27.3 0.1 3.9 4 1 0 4 4 4 2 Glycosyl hydrolase family 63 C-terminal domain V-SNARE_C PF12352.8 KSA02279.1 - 4.8e-18 65.2 5.0 4.8e-18 65.2 5.0 2.2 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.15 KSA02279.1 - 2.9e-09 37.2 1.4 2.9e-09 37.2 1.4 2.3 2 1 1 3 3 3 1 Vesicle transport v-SNARE protein N-terminus Sec20 PF03908.13 KSA02279.1 - 0.021 14.7 0.8 0.021 14.7 0.8 2.0 2 0 0 2 2 2 0 Sec20 Receptor_2B4 PF11465.8 KSA02279.1 - 0.028 14.6 0.2 0.043 14.0 0.2 1.2 1 0 0 1 1 1 0 Natural killer cell receptor 2B4 STAT_alpha PF01017.20 KSA02279.1 - 0.057 13.3 5.3 0.092 12.6 5.2 1.5 1 1 0 1 1 1 0 STAT protein, all-alpha domain YqjK PF13997.6 KSA02279.1 - 0.1 12.9 0.5 4.1 7.7 0.0 2.5 2 0 0 2 2 2 0 YqjK-like protein DUF4570 PF15134.6 KSA02279.1 - 8.1 6.5 7.8 1.4 9.0 2.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4570) Fer2 PF00111.27 KSA02280.1 - 7.1e-14 51.5 0.3 9.2e-14 51.2 0.3 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain KDZ PF18758.1 KSA02280.1 - 0.042 13.4 0.0 0.062 12.9 0.0 1.2 1 0 0 1 1 1 0 Kyakuja-Dileera-Zisupton transposase Microtub_bd PF16796.5 KSA02281.1 - 5.5e-23 81.5 4.3 5.5e-23 81.5 4.3 3.0 2 1 1 3 3 3 1 Microtubule binding zf-C2H2_3rep PF18868.1 KSA02281.1 - 0.23 12.1 7.6 3.4 8.3 1.4 3.0 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats HR1 PF02185.16 KSA02281.1 - 0.39 10.9 9.4 4.6 7.4 0.3 3.7 2 1 0 2 2 2 0 Hr1 repeat CLZ PF16526.5 KSA02281.1 - 0.83 10.0 15.3 5.5 7.4 0.6 4.5 3 1 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels FlaC_arch PF05377.11 KSA02281.1 - 4.6 7.7 20.0 2.9 8.3 1.3 4.3 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF489 PF04356.12 KSA02281.1 - 7 6.6 14.5 2.4 8.1 2.4 2.8 1 1 0 2 2 2 0 Protein of unknown function (DUF489) SAGA-Tad1 PF12767.7 KSA02282.1 - 1.2e-56 192.1 2.0 1.2e-56 192.1 2.0 2.5 2 1 0 2 2 2 1 Transcriptional regulator of RNA polII, SAGA, subunit TAF4 PF05236.14 KSA02282.1 - 0.0013 18.5 7.9 0.005 16.6 7.9 1.9 1 1 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family MFS_1 PF07690.16 KSA02283.1 - 1.3e-33 116.4 63.2 1.5e-32 112.9 58.9 2.8 1 1 0 2 2 2 2 Major Facilitator Superfamily Sybindin PF04099.12 KSA02284.1 - 1.8e-09 37.6 0.8 3.2e-09 36.9 0.2 1.6 1 1 1 2 2 2 1 Sybindin-like family Ecl1 PF12855.7 KSA02285.1 - 0.037 15.2 4.7 0.042 15.0 4.7 1.3 1 1 0 1 1 1 0 ECL1/2/3 zinc binding proteins zf-FLZ PF04570.14 KSA02285.1 - 0.053 13.0 3.6 1.1 8.8 0.4 2.3 2 0 0 2 2 2 0 zinc-finger of the FCS-type, C2-C2 SAC3_GANP PF03399.16 KSA02286.1 - 8.2e-107 356.9 0.2 1.5e-106 356.1 0.2 1.4 1 0 0 1 1 1 1 SAC3/GANP family SAC3 PF12209.8 KSA02286.1 - 3.2e-25 88.1 3.7 3.2e-25 88.1 3.7 2.5 3 0 0 3 3 3 1 Leucine permease transcriptional regulator helical domain Ndr PF03096.14 KSA02286.1 - 0.086 11.5 0.8 0.21 10.2 0.8 1.7 1 0 0 1 1 1 0 Ndr family Semialdhyde_dhC PF02774.18 KSA02287.1 - 4.2e-40 137.8 0.0 6.1e-40 137.3 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 KSA02287.1 - 4.3e-31 107.9 0.0 7.5e-31 107.1 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DXP_reductoisom PF02670.16 KSA02287.1 - 0.00097 19.9 0.0 0.0028 18.4 0.0 1.8 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase Sacchrp_dh_NADP PF03435.18 KSA02287.1 - 0.046 14.0 0.0 0.089 13.1 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain SSrecog PF03531.14 KSA02288.1 - 3.7e-32 110.0 0.7 9.6e-30 102.3 0.1 3.9 3 0 0 3 3 3 1 Structure-specific recognition protein (SSRP1) POB3_N PF17292.2 KSA02288.1 - 4.8e-29 100.6 0.2 3.7e-26 91.4 0.1 3.2 3 0 0 3 3 3 2 POB3-like N-terminal PH domain Rtt106 PF08512.12 KSA02288.1 - 7.5e-28 96.8 0.0 4.4e-26 91.1 0.0 3.3 4 0 0 4 4 4 1 Histone chaperone Rttp106-like Mem_trans PF03547.18 KSA02290.1 - 2.4e-35 121.7 0.0 5.5e-35 120.5 0.0 1.5 1 1 0 1 1 1 1 Membrane transport protein DUF996 PF06195.13 KSA02290.1 - 2.4 8.5 11.0 0.079 13.2 2.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF996) Bap31 PF05529.12 KSA02291.1 - 6.8e-48 162.0 1.7 9.3e-48 161.5 1.7 1.2 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 KSA02291.1 - 1.8e-06 27.8 7.0 3.7e-06 26.8 7.0 1.5 1 0 0 1 1 1 1 Bap31/Bap29 cytoplasmic coiled-coil domain DivIC PF04977.15 KSA02291.1 - 0.026 14.3 4.0 0.1 12.4 3.1 2.3 2 1 1 3 3 3 0 Septum formation initiator DUF148 PF02520.17 KSA02291.1 - 0.027 14.6 0.3 0.044 13.9 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF148 Clp1 PF06807.14 KSA02291.1 - 0.042 14.3 0.0 0.092 13.2 0.0 1.5 1 0 0 1 1 1 0 Pre-mRNA cleavage complex II protein Clp1 Spc7 PF08317.11 KSA02291.1 - 0.044 12.7 3.9 0.056 12.3 3.9 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Dus PF01207.17 KSA02292.1 - 5.5e-46 157.1 0.5 2.3e-44 151.7 0.0 2.4 2 1 0 2 2 2 1 Dihydrouridine synthase (Dus) zf-CCCH_4 PF18044.1 KSA02292.1 - 0.42 10.5 5.7 1.4 8.8 1.1 2.5 2 0 0 2 2 2 0 CCCH-type zinc finger zf-CCCH PF00642.24 KSA02292.1 - 0.71 9.9 4.0 0.29 11.1 0.5 2.1 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KSA02292.1 - 8.8 6.5 7.4 2.3 8.4 0.6 2.8 2 1 0 2 2 2 0 Zinc finger domain Utp21 PF04192.12 KSA02293.1 - 5.8e-79 264.9 0.8 8.8e-79 264.3 0.8 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain ANAPC4_WD40 PF12894.7 KSA02293.1 - 8.4e-14 51.7 0.0 0.00039 20.7 0.0 5.1 3 2 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KSA02293.1 - 2.1e-10 41.0 7.3 2.9e-06 27.9 0.1 7.0 7 0 0 7 7 7 1 WD domain, G-beta repeat WD40_like PF17005.5 KSA02293.1 - 0.042 13.2 2.9 0.18 11.1 0.0 2.8 4 0 0 4 4 4 0 WD40-like domain Cytochrom_D1 PF02239.16 KSA02293.1 - 0.17 10.4 0.0 0.34 9.4 0.0 1.4 1 0 0 1 1 1 0 Cytochrome D1 heme domain Vps39_1 PF10366.9 KSA02294.1 - 4.5e-34 117.0 0.2 4.5e-34 117.0 0.2 4.0 4 1 1 5 5 5 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.9 KSA02294.1 - 4.1e-18 65.8 2.0 9e-18 64.7 0.0 2.7 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.22 KSA02294.1 - 2.3e-12 47.1 0.2 6.1e-12 45.7 0.2 1.7 1 0 0 1 1 1 1 CNH domain Rxt3 PF08642.10 KSA02295.1 - 1.8e-21 77.2 0.0 1.8e-21 77.2 0.0 4.8 2 2 0 2 2 2 1 Histone deacetylation protein Rxt3 DUF4050 PF13259.6 KSA02296.1 - 2.1e-17 64.0 4.9 1.6e-13 51.4 0.4 3.4 1 1 2 3 3 3 2 Protein of unknown function (DUF4050) BLOC1_2 PF10046.9 KSA02296.1 - 0.075 13.3 1.1 0.2 12.0 1.1 1.7 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 MMTV_SAg PF01054.17 KSA02296.1 - 0.18 11.4 2.2 0.34 10.4 2.2 1.7 1 1 0 1 1 1 0 Mouse mammary tumour virus superantigen PilJ PF13675.6 KSA02297.1 - 0.023 14.7 0.7 0.044 13.8 0.2 1.7 1 1 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term Acetyltransf_14 PF03421.16 KSA02297.1 - 0.03 14.4 1.0 0.052 13.6 1.0 1.4 1 0 0 1 1 1 0 YopJ Serine/Threonine acetyltransferase DUF1430 PF07242.11 KSA02298.1 - 0.0036 17.5 2.4 0.019 15.2 2.4 2.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1430) Ribosomal_L31e PF01198.19 KSA02299.1 - 5.6e-39 132.3 1.0 7.5e-39 131.9 1.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L31e AAA PF00004.29 KSA02300.1 - 7e-58 194.8 0.0 7e-43 146.2 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KSA02300.1 - 6.2e-10 38.7 2.2 0.00046 19.9 0.1 3.1 3 0 0 3 3 2 2 AAA+ lid domain AAA_16 PF13191.6 KSA02300.1 - 1.2e-06 29.1 0.0 0.028 14.8 0.0 3.5 3 0 0 3 3 3 1 AAA ATPase domain AAA_2 PF07724.14 KSA02300.1 - 1.8e-06 28.2 0.1 0.0065 16.6 0.0 3.3 3 1 0 3 3 3 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 KSA02300.1 - 6.5e-06 26.0 0.0 0.0013 18.4 0.0 2.5 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 KSA02300.1 - 7.8e-05 22.7 0.1 0.22 11.6 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 KSA02300.1 - 0.00026 21.2 0.0 0.53 10.4 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.6 KSA02300.1 - 0.00027 21.5 0.0 0.13 12.8 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KSA02300.1 - 0.00027 21.2 0.1 0.047 14.0 0.0 3.1 2 1 0 2 2 2 1 AAA domain Parvo_NS1 PF01057.17 KSA02300.1 - 0.00029 20.0 0.0 0.00056 19.1 0.0 1.4 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 RNA_helicase PF00910.22 KSA02300.1 - 0.00074 19.9 0.0 0.019 15.3 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_14 PF13173.6 KSA02300.1 - 0.0021 18.1 0.0 0.46 10.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KSA02300.1 - 0.0025 18.1 0.0 0.18 12.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 KSA02300.1 - 0.0044 16.9 0.5 0.28 11.1 0.6 3.0 2 1 0 2 2 2 1 Rad17 P-loop domain AAA_5 PF07728.14 KSA02300.1 - 0.0046 17.0 0.2 0.07 13.1 0.0 3.1 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 KSA02300.1 - 0.0046 16.7 0.0 0.016 15.0 0.0 1.8 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_7 PF12775.7 KSA02300.1 - 0.005 16.4 0.0 0.03 13.8 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region TIP49 PF06068.13 KSA02300.1 - 0.0081 15.4 0.0 0.029 13.6 0.0 1.9 2 0 0 2 2 2 1 TIP49 P-loop domain Vps4_C PF09336.10 KSA02300.1 - 0.0086 16.1 0.2 0.038 14.0 0.0 2.2 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain NACHT PF05729.12 KSA02300.1 - 0.0092 15.9 0.0 3.4 7.6 0.0 2.8 2 0 0 2 2 2 1 NACHT domain ATPase PF06745.13 KSA02300.1 - 0.0099 15.3 0.0 0.024 14.0 0.0 1.6 1 0 0 1 1 1 1 KaiC Mg_chelatase PF01078.21 KSA02300.1 - 0.016 14.6 0.0 0.046 13.1 0.0 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 KSA02300.1 - 0.02 14.7 0.0 0.58 9.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.11 KSA02300.1 - 0.021 14.7 0.0 1.7 8.5 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KSA02300.1 - 0.034 13.3 0.0 3.9 6.6 0.0 3.1 3 0 0 3 3 3 0 NB-ARC domain AAA_17 PF13207.6 KSA02300.1 - 0.035 14.5 0.0 3.4 8.1 0.0 3.3 3 0 0 3 3 3 0 AAA domain SKI PF01202.22 KSA02300.1 - 0.038 14.1 0.0 3.3 7.8 0.0 2.8 2 0 0 2 2 2 0 Shikimate kinase AAA_25 PF13481.6 KSA02300.1 - 0.08 12.5 0.5 0.61 9.6 0.0 2.3 2 1 1 3 3 3 0 AAA domain PhoH PF02562.16 KSA02300.1 - 0.087 12.3 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein KH_dom-like PF14714.6 KSA02300.1 - 0.16 12.3 0.6 1 9.7 0.1 2.6 2 0 0 2 2 2 0 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal ABC_tran PF00005.27 KSA02300.1 - 0.42 11.1 1.7 2.2 8.8 0.0 2.7 3 0 0 3 3 2 0 ABC transporter DnaJ PF00226.31 KSA02301.1 - 5e-05 23.4 0.4 0.00014 21.9 0.1 1.9 2 0 0 2 2 2 1 DnaJ domain Pam16 PF03656.13 KSA02301.1 - 0.0011 18.9 0.1 0.0015 18.5 0.1 1.2 1 0 0 1 1 1 1 Pam16 DUF5353 PF17304.2 KSA02301.1 - 0.37 10.6 1.1 0.6 9.9 0.1 1.8 3 0 0 3 3 3 0 Family of unknown function (DUF5353) PK PF00224.21 KSA02302.1 - 7.2e-170 564.4 4.6 9.5e-170 564.1 4.6 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 KSA02302.1 - 1.7e-38 131.4 0.1 5.1e-38 129.9 0.1 1.9 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 KSA02302.1 - 4.9e-05 22.6 0.3 0.00012 21.3 0.1 1.7 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family Ubie_methyltran PF01209.18 KSA02303.1 - 2.2e-88 295.5 0.0 2.8e-88 295.2 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 KSA02303.1 - 4.4e-12 46.5 0.0 1e-11 45.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KSA02303.1 - 2.7e-10 40.7 0.0 5e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KSA02303.1 - 5.4e-10 39.3 0.0 4.7e-09 36.2 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KSA02303.1 - 3.6e-08 34.0 0.2 7.9e-08 33.0 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KSA02303.1 - 0.0001 22.2 0.0 0.00015 21.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 KSA02303.1 - 0.021 14.6 0.0 0.45 10.3 0.0 2.2 2 0 0 2 2 2 0 Hypothetical methyltransferase Med1 PF10744.9 KSA02304.1 - 3.5e-66 224.0 7.8 5.5e-66 223.3 7.8 1.3 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 Usher PF00577.20 KSA02304.1 - 0.13 11.1 7.8 0.2 10.5 7.8 1.2 1 0 0 1 1 1 0 Outer membrane usher protein IF-2B PF01008.17 KSA02305.1 - 1.3e-67 228.0 1.3 1.7e-67 227.6 1.3 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family ABC_sub_bind PF04392.12 KSA02305.1 - 0.0037 16.6 0.2 0.0037 16.6 0.2 1.8 2 0 0 2 2 2 1 ABC transporter substrate binding protein LRR_4 PF12799.7 KSA02307.1 - 6.8e-35 118.5 48.0 1.5e-09 38.0 3.8 7.3 2 2 6 9 9 9 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KSA02307.1 - 8.1e-22 76.8 39.2 2.4e-05 24.0 2.7 5.8 3 2 2 6 6 6 6 Leucine rich repeat LRR_9 PF14580.6 KSA02307.1 - 2.6e-14 53.1 23.1 3e-08 33.3 9.9 4.3 1 1 3 4 4 4 4 Leucine-rich repeat LRR_6 PF13516.6 KSA02307.1 - 0.0079 16.2 33.8 0.64 10.2 0.8 7.8 9 0 0 9 9 9 4 Leucine Rich repeat UB2H PF14814.6 KSA02307.1 - 0.46 10.5 4.4 68 3.6 0.1 4.6 2 2 3 5 5 5 0 Bifunctional transglycosylase second domain LRR_2 PF07723.13 KSA02307.1 - 2.6 8.9 4.4 12 6.8 0.0 4.0 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_1 PF00560.33 KSA02307.1 - 4.3 8.3 38.8 6.5 7.7 0.4 9.5 10 1 0 10 10 10 0 Leucine Rich Repeat PP-binding PF00550.25 KSA02308.1 - 2.6e-10 40.5 0.8 4.4e-10 39.8 0.7 1.4 1 1 1 2 2 2 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 KSA02308.1 - 1.6e-05 25.1 0.6 3.4e-05 24.0 0.4 1.6 1 1 1 2 2 2 1 Acyl-carrier DHR-2 PF06920.13 KSA02309.1 - 1.7e-43 149.1 0.1 7.7e-43 146.9 0.1 1.9 1 1 0 1 1 1 1 Dock homology region 2 DOCK_N PF16172.5 KSA02309.1 - 3.8e-17 62.3 0.6 2.3e-10 40.0 0.0 2.9 3 0 0 3 3 3 2 DOCK N-terminus AA_permease PF00324.21 KSA02310.1 - 1.6e-82 277.7 42.7 1.2e-80 271.4 42.7 2.0 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KSA02310.1 - 3.3e-24 85.5 36.6 6e-24 84.6 36.6 1.5 1 1 0 1 1 1 1 Amino acid permease Sugar_tr PF00083.24 KSA02312.1 - 1.5e-32 113.1 27.1 4.7e-21 75.2 5.9 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KSA02312.1 - 1.8e-19 69.9 33.1 6.3e-10 38.5 14.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Amidohydro_2 PF04909.14 KSA02313.1 - 1.1e-06 28.6 0.0 2.6e-06 27.5 0.0 1.6 1 1 0 1 1 1 1 Amidohydrolase DIM1 PF02966.16 KSA02316.1 - 4.2e-68 227.2 0.3 4.7e-68 227.0 0.3 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 KSA02316.1 - 0.027 14.4 0.0 0.037 14.0 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin PBP PF01161.20 KSA02317.1 - 2e-22 79.9 0.2 2.5e-22 79.6 0.2 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein CBFD_NFYB_HMF PF00808.23 KSA02318.1 - 1.5e-19 70.0 0.6 2.9e-19 69.1 0.6 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KSA02318.1 - 3.7e-16 59.7 0.3 3.7e-16 59.7 0.3 2.9 2 1 1 3 3 3 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.10 KSA02318.1 - 0.013 15.8 0.1 0.059 13.7 0.1 2.1 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Paramyxo_ncap PF00973.19 KSA02318.1 - 0.79 8.6 7.1 1.5 7.7 7.1 1.3 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Peptidase_U57 PF05582.12 KSA02318.1 - 1.1 8.4 5.6 2.1 7.5 5.6 1.4 1 0 0 1 1 1 0 YabG peptidase U57 CDK5_activator PF03261.15 KSA02318.1 - 8.5 5.8 18.8 6.1 6.3 17.0 1.6 1 1 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein PepSY_TM PF03929.16 KSA02318.1 - 9.6 5.8 11.4 6.3 6.4 0.5 2.3 2 0 0 2 2 2 0 PepSY-associated TM region Ras PF00071.22 KSA02319.1 - 1.9e-59 199.9 0.1 2.2e-59 199.7 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KSA02319.1 - 5.3e-35 120.2 0.0 8.1e-35 119.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KSA02319.1 - 1.1e-14 54.3 0.0 1.3e-14 54.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KSA02319.1 - 3.7e-06 26.5 0.0 4.8e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KSA02319.1 - 2.9e-05 24.1 0.0 4.1e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KSA02319.1 - 0.00017 21.6 0.1 0.33 10.8 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 KSA02319.1 - 0.00044 20.7 0.0 0.00056 20.3 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain GTP_EFTU PF00009.27 KSA02319.1 - 0.00083 18.9 0.0 0.0015 18.1 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain NMT1 PF09084.11 KSA02320.1 - 5.6e-17 62.4 0.0 5.4e-12 46.1 0.0 2.2 2 0 0 2 2 2 2 NMT1/THI5 like SBP_bac_3 PF00497.20 KSA02320.1 - 2.6e-05 23.8 0.0 4.4e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 NMT1_2 PF13379.6 KSA02320.1 - 0.00019 21.2 0.0 0.0009 19.0 0.0 1.9 2 0 0 2 2 2 1 NMT1-like family LysR_substrate PF03466.20 KSA02320.1 - 0.019 14.3 0.0 0.03 13.7 0.0 1.2 1 0 0 1 1 1 0 LysR substrate binding domain DUF3834 PF12916.7 KSA02320.1 - 0.033 13.4 0.0 0.078 12.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3834) SBP_bac_11 PF13531.6 KSA02320.1 - 0.15 11.8 0.0 1.1 9.0 0.0 2.0 2 0 0 2 2 2 0 Bacterial extracellular solute-binding protein Y_phosphatase PF00102.27 KSA02321.1 - 3.6e-56 190.3 0.1 4.8e-56 190.0 0.1 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KSA02321.1 - 0.0024 17.9 0.0 0.0038 17.2 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 KSA02321.1 - 0.0078 16.3 0.0 0.03 14.5 0.0 2.1 2 0 0 2 2 2 1 Inositol hexakisphosphate DSPc PF00782.20 KSA02321.1 - 0.035 13.9 0.0 0.075 12.8 0.0 1.6 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain KH_1 PF00013.29 KSA02322.1 - 2e-07 30.7 0.0 6.5e-07 29.1 0.0 1.9 2 0 0 2 2 2 1 KH domain HSP70 PF00012.20 KSA02323.1 - 5.8e-229 761.2 10.6 6.5e-229 761.1 10.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KSA02323.1 - 3.7e-16 58.9 0.6 2.2e-14 53.0 0.3 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 KSA02323.1 - 0.0011 18.8 0.0 0.003 17.3 0.0 1.8 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain ATP-synt_DE PF00401.20 KSA02323.1 - 0.0077 16.5 6.7 0.016 15.5 2.4 3.0 2 1 0 2 2 2 1 ATP synthase, Delta/Epsilon chain, long alpha-helix domain BcrAD_BadFG PF01869.20 KSA02323.1 - 0.077 12.5 2.1 7 6.1 0.1 2.8 3 1 0 3 3 3 0 BadF/BadG/BcrA/BcrD ATPase family RIO1 PF01163.22 KSA02324.1 - 3.8e-41 140.8 1.4 6.8e-41 139.9 1.4 1.4 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.11 KSA02324.1 - 3.1e-33 113.8 0.1 1e-32 112.2 0.0 1.9 2 0 0 2 2 2 1 Rio2, N-terminal Kdo PF06293.14 KSA02324.1 - 1.5e-05 24.5 0.5 0.00078 18.9 0.5 2.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KSA02324.1 - 0.00018 21.5 0.4 0.86 9.5 0.0 2.8 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.25 KSA02324.1 - 0.054 12.9 0.2 0.091 12.1 0.2 1.4 1 0 0 1 1 1 0 Protein kinase domain NOA36 PF06524.12 KSA02324.1 - 0.23 10.7 14.1 0.36 10.1 14.1 1.2 1 0 0 1 1 1 0 NOA36 protein RRN3 PF05327.11 KSA02324.1 - 9.5 4.6 14.2 14 4.1 14.2 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Lon_C PF05362.13 KSA02325.1 - 0.16 11.5 0.0 0.33 10.5 0.0 1.4 1 0 0 1 1 1 0 Lon protease (S16) C-terminal proteolytic domain DCP2 PF05026.13 KSA02326.1 - 1.9e-27 95.4 0.1 4.3e-27 94.3 0.1 1.6 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 KSA02326.1 - 1.4e-14 54.2 0.0 3.6e-14 52.9 0.0 1.7 1 0 0 1 1 1 1 NUDIX domain NUC129 PF08157.11 KSA02326.1 - 8.3 6.9 5.8 72 3.9 0.1 3.9 3 1 1 4 4 4 0 NUC129 domain ATP-synt_10 PF05176.14 KSA02327.1 - 3.3e-94 314.9 0.0 3.8e-94 314.7 0.0 1.0 1 0 0 1 1 1 1 ATP10 protein Ribosomal_S10 PF00338.22 KSA02329.1 - 5.3e-26 90.7 1.3 6.5e-26 90.4 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e PP2C PF00481.21 KSA02330.1 - 2.1e-44 152.1 0.0 4.2e-44 151.1 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KSA02330.1 - 0.18 11.7 0.0 1.9 8.4 0.0 2.3 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) Ski2_N PF17911.1 KSA02331.1 - 1.9e-37 128.1 0.1 3.9e-37 127.1 0.1 1.4 1 0 0 1 1 1 1 Ski2 N-terminal region DEAD PF00270.29 KSA02331.1 - 1e-20 74.2 0.0 2.1e-20 73.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KSA02331.1 - 2.8e-07 30.9 0.0 1.6e-06 28.4 0.0 2.4 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KSA02331.1 - 9.2e-06 25.8 0.1 1.9e-05 24.7 0.1 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DSHCT PF08148.12 KSA02332.1 - 1.6e-49 167.7 1.0 3.3e-49 166.7 1.0 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain rRNA_proc-arch PF13234.6 KSA02332.1 - 2.6e-06 27.6 0.4 4.9e-06 26.7 0.0 1.6 2 0 0 2 2 2 1 rRNA-processing arch domain PerB PF06590.11 KSA02333.1 - 0.01 16.4 0.0 0.018 15.6 0.0 1.3 1 0 0 1 1 1 0 PerB protein CDC48_N PF02359.18 KSA02334.1 - 3.8e-05 23.8 0.2 0.00013 22.1 0.0 1.9 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain AAA PF00004.29 KSA02335.1 - 2.3e-80 267.5 0.0 1.5e-43 148.4 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KSA02335.1 - 3.1e-25 87.7 0.6 2.1e-11 43.5 0.0 2.6 2 0 0 2 2 2 2 AAA+ lid domain AAA_2 PF07724.14 KSA02335.1 - 1.4e-08 35.0 0.1 0.0083 16.3 0.0 3.2 3 1 0 3 3 3 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 KSA02335.1 - 7.6e-06 25.8 0.0 0.00015 21.6 0.0 2.8 3 1 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KSA02335.1 - 3.8e-05 23.7 0.1 0.0048 16.9 0.0 3.6 2 2 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KSA02335.1 - 0.00013 22.4 0.0 0.71 10.2 0.1 3.6 2 1 2 4 4 4 1 AAA ATPase domain Bac_DnaA PF00308.18 KSA02335.1 - 0.0007 19.5 0.0 0.1 12.4 0.0 2.4 2 0 0 2 2 2 1 Bacterial dnaA protein Rad17 PF03215.15 KSA02335.1 - 0.00089 19.2 0.3 0.02 14.8 0.2 2.7 2 1 1 3 3 3 1 Rad17 P-loop domain AAA_14 PF13173.6 KSA02335.1 - 0.0012 18.9 0.0 0.53 10.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 KSA02335.1 - 0.002 17.4 0.0 0.0039 16.5 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 KSA02335.1 - 0.0053 17.0 0.1 5.9 7.2 0.1 3.5 3 1 1 4 4 3 1 AAA domain AAA_25 PF13481.6 KSA02335.1 - 0.01 15.4 1.7 9.5 5.7 0.0 3.2 2 1 0 3 3 3 0 AAA domain BAR PF03114.18 KSA02335.1 - 0.025 14.3 0.3 0.082 12.5 0.1 1.9 2 0 0 2 2 2 0 BAR domain Vps4_C PF09336.10 KSA02335.1 - 0.052 13.6 0.1 9.6 6.3 0.0 2.9 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain KORA PF16509.5 KSA02335.1 - 0.057 13.7 0.0 0.15 12.3 0.0 1.7 1 0 0 1 1 1 0 TrfB plasmid transcriptional repressor RNA_helicase PF00910.22 KSA02335.1 - 0.071 13.5 0.0 0.33 11.4 0.0 2.1 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.6 KSA02335.1 - 0.084 13.0 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 KSA02335.1 - 0.11 12.6 0.0 1 9.5 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain ATPase PF06745.13 KSA02335.1 - 0.12 11.6 0.0 5.3 6.3 0.0 2.6 3 0 0 3 3 3 0 KaiC Pex19 PF04614.12 KSA02336.1 - 1.6e-67 227.8 5.6 1.6e-67 227.8 5.6 2.0 2 0 0 2 2 2 1 Pex19 protein family CDC37_N PF03234.14 KSA02336.1 - 0.022 15.7 4.5 0.022 15.7 4.5 2.6 3 0 0 3 3 3 0 Cdc37 N terminal kinase binding Uteroglobin PF01099.17 KSA02336.1 - 0.14 12.5 1.1 0.46 10.9 1.1 2.0 1 0 0 1 1 1 0 Uteroglobin family Lipase_GDSL_3 PF14606.6 KSA02336.1 - 0.2 11.7 0.5 0.48 10.5 0.5 1.6 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family UPF0172 PF03665.13 KSA02336.1 - 0.67 10.0 6.2 0.09 12.8 1.7 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0172) Goodbye PF17109.5 KSA02336.1 - 2.1 8.8 4.5 1.3 9.5 1.0 2.4 2 1 1 3 3 3 0 fungal STAND N-terminal Goodbye domain ApoLp-III PF07464.11 KSA02336.1 - 4.6 7.3 16.6 0.087 12.9 1.5 3.8 3 2 1 4 4 4 0 Apolipophorin-III precursor (apoLp-III) DUF445 PF04286.12 KSA02336.1 - 5.7 6.6 8.7 12 5.6 8.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF445) UQ_con PF00179.26 KSA02337.1 - 2.6e-45 153.5 0.1 2.9e-45 153.4 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KSA02337.1 - 6.5e-05 22.6 0.0 8.4e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KSA02337.1 - 0.0077 16.5 2.9 0.023 15.0 2.9 1.9 1 1 0 1 1 1 1 RWD domain UEV PF05743.13 KSA02337.1 - 0.046 13.6 0.9 0.14 12.0 0.8 1.7 1 1 0 1 1 1 0 UEV domain 6PF2K PF01591.18 KSA02338.1 - 4.5e-83 277.9 4.1 8.1e-83 277.1 4.1 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KSA02338.1 - 5.2e-36 124.2 0.0 7.2e-36 123.7 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 KSA02338.1 - 0.00013 22.1 0.0 0.00024 21.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 KSA02338.1 - 0.00017 21.1 0.6 0.00026 20.5 0.6 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 hSac2 PF12456.8 KSA02338.1 - 0.0096 15.6 0.0 0.026 14.2 0.0 1.7 1 0 0 1 1 1 1 Inositol phosphatase AAA_17 PF13207.6 KSA02338.1 - 0.059 13.8 0.0 2.4 8.6 0.0 2.3 1 1 1 2 2 2 0 AAA domain Peptidase_S64 PF08192.11 KSA02339.1 - 3.5e-265 881.9 23.1 2.1e-264 879.4 23.1 1.9 1 1 0 1 1 1 1 Peptidase family S64 TMEM206 PF15122.6 KSA02339.1 - 0.045 12.9 0.3 0.082 12.1 0.3 1.3 1 0 0 1 1 1 0 TMEM206 protein family MF_alpha_N PF05436.11 KSA02340.1 - 0.13 12.2 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 Mating factor alpha precursor N-terminus RIBIOP_C PF04950.12 KSA02342.1 - 1e-106 356.7 0.9 1.4e-106 356.2 0.0 1.7 2 0 0 2 2 2 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 KSA02342.1 - 6.3e-26 90.3 0.0 1.5e-25 89.1 0.0 1.7 1 0 0 1 1 1 1 AARP2CN (NUC121) domain RPAP1_N PF08621.10 KSA02342.1 - 0.61 9.9 4.7 0.72 9.7 2.2 2.4 2 0 0 2 2 2 0 RPAP1-like, N-terminal zf-C2H2_2 PF12756.7 KSA02343.1 - 5.3e-33 113.4 3.7 4e-30 104.1 0.3 2.9 2 1 1 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 KSA02343.1 - 0.0018 18.6 7.4 0.005 17.2 0.3 3.1 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2HE PF16278.5 KSA02343.1 - 0.0035 17.7 0.9 0.77 10.3 0.0 3.4 3 0 0 3 3 3 1 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_12 PF18658.1 KSA02343.1 - 0.033 13.7 1.0 0.17 11.5 0.0 2.6 4 0 0 4 4 4 0 Zinc-finger C2H2-type AKAP95 PF04988.12 KSA02343.1 - 0.068 13.4 3.7 4 7.6 0.7 2.6 2 1 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_jaz PF12171.8 KSA02343.1 - 0.17 12.2 0.0 0.17 12.2 0.0 3.7 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KSA02343.1 - 0.75 10.8 0.1 0.75 10.8 0.1 3.6 4 0 0 4 4 4 0 C2H2-type zinc finger DnaJ_C PF01556.18 KSA02344.1 - 2.8e-26 92.4 0.1 2.4e-25 89.4 0.1 2.2 1 1 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KSA02344.1 - 4.9e-22 77.8 0.9 1.1e-21 76.7 0.9 1.6 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KSA02344.1 - 1e-09 38.6 8.4 3.3e-09 37.0 8.4 1.9 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KSA02344.1 - 2 8.5 5.0 9.1 6.3 0.4 2.7 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein Vac14_Fig4_bd PF11916.8 KSA02346.1 - 1.8e-68 229.7 12.3 4.2e-68 228.5 12.3 1.7 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 KSA02346.1 - 2.6e-35 120.9 1.2 6.6e-35 119.6 0.3 2.3 2 0 0 2 2 2 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KSA02346.1 - 0.00045 20.3 11.4 0.047 13.7 0.1 3.8 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KSA02346.1 - 0.00058 19.9 0.3 0.033 14.5 0.0 3.7 3 0 0 3 3 3 1 HEAT repeat HEAT_EZ PF13513.6 KSA02346.1 - 0.00065 20.1 0.0 0.31 11.6 0.0 3.6 2 1 1 3 3 3 1 HEAT-like repeat HEAT_2 PF13646.6 KSA02346.1 - 0.0067 16.8 0.0 0.15 12.5 0.0 3.2 2 1 1 3 3 3 1 HEAT repeats DUF4996 PF16387.5 KSA02346.1 - 0.094 13.2 0.7 1.5 9.4 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function RuvC_III PF18541.1 KSA02347.1 - 0.0038 17.2 3.0 0.0089 16.0 3.0 1.6 1 0 0 1 1 1 1 RuvC endonuclease subdomain 3 Myb_DNA-bind_3 PF12776.7 KSA02347.1 - 0.011 16.7 0.3 0.011 16.7 0.3 2.5 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Tropomyosin_1 PF12718.7 KSA02349.1 - 4e-50 169.7 41.0 5.2e-50 169.3 41.0 1.1 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.20 KSA02349.1 - 6.8e-07 28.9 39.2 0.00043 19.7 21.6 2.0 1 1 1 2 2 2 2 Tropomyosin GAS PF13851.6 KSA02349.1 - 3.4e-06 26.5 38.0 3.1e-05 23.4 38.0 2.1 1 1 0 1 1 1 1 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.9 KSA02349.1 - 1.6e-05 24.9 42.9 1.8e-05 24.8 13.1 3.2 1 1 2 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.11 KSA02349.1 - 2.1e-05 24.8 37.8 0.002 18.4 21.6 2.0 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) Laminin_II PF06009.12 KSA02349.1 - 7e-05 22.9 25.1 0.0074 16.3 10.1 2.0 1 1 1 2 2 2 2 Laminin Domain II DHR10 PF18595.1 KSA02349.1 - 0.0012 18.8 38.0 0.085 12.9 17.0 2.3 1 1 0 2 2 2 2 Designed helical repeat protein 10 domain TMF_DNA_bd PF12329.8 KSA02349.1 - 0.0013 18.6 14.9 0.0013 18.6 14.9 3.4 1 1 2 3 3 3 1 TATA element modulatory factor 1 DNA binding Rho_Binding PF08912.11 KSA02349.1 - 0.0035 18.1 5.5 0.0035 18.1 5.5 4.0 1 1 3 4 4 4 1 Rho Binding Fez1 PF06818.15 KSA02349.1 - 0.0042 17.6 33.7 0.0063 17.0 29.1 2.0 1 1 1 2 2 2 2 Fez1 Taxilin PF09728.9 KSA02349.1 - 0.0046 16.2 11.0 0.0046 16.2 11.0 2.3 1 1 1 2 2 2 1 Myosin-like coiled-coil protein DUF724 PF05266.14 KSA02349.1 - 0.0047 16.8 33.7 0.018 14.9 16.8 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF724) Nup54 PF13874.6 KSA02349.1 - 0.0056 16.8 23.3 0.083 13.0 13.8 2.1 1 1 1 2 2 2 2 Nucleoporin complex subunit 54 APG6_N PF17675.1 KSA02349.1 - 0.006 17.1 48.0 0.034 14.7 27.5 2.1 1 1 1 2 2 2 1 Apg6 coiled-coil region Filament PF00038.21 KSA02349.1 - 0.0062 16.1 33.4 0.013 15.1 19.3 2.1 1 1 1 2 2 2 1 Intermediate filament protein FliD_C PF07195.12 KSA02349.1 - 0.0089 15.5 21.3 0.09 12.2 13.0 2.2 1 1 1 2 2 2 2 Flagellar hook-associated protein 2 C-terminus DUF3450 PF11932.8 KSA02349.1 - 0.012 15.0 33.4 0.076 12.3 13.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF4315 PF14193.6 KSA02349.1 - 0.018 15.1 10.5 0.018 15.1 10.5 4.1 2 1 1 3 3 2 0 Domain of unknown function (DUF4315) LPP PF04728.13 KSA02349.1 - 0.019 15.4 15.1 0.24 11.8 1.5 4.1 2 2 2 4 4 3 0 Lipoprotein leucine-zipper FlaC_arch PF05377.11 KSA02349.1 - 0.021 15.2 30.7 0.037 14.4 0.8 4.7 1 1 4 5 5 4 0 Flagella accessory protein C (FlaC) KASH_CCD PF14662.6 KSA02349.1 - 0.025 14.4 40.8 0.076 12.8 29.7 2.3 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH DivIC PF04977.15 KSA02349.1 - 0.026 14.3 9.0 0.026 14.3 9.0 4.3 1 1 3 4 4 3 0 Septum formation initiator DUF1664 PF07889.12 KSA02349.1 - 0.029 14.4 20.8 0.2 11.7 6.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Uso1_p115_C PF04871.13 KSA02349.1 - 0.033 14.6 41.1 0.49 10.8 20.7 2.1 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Jnk-SapK_ap_N PF09744.9 KSA02349.1 - 0.034 14.4 39.3 0.025 14.8 28.5 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Prefoldin_2 PF01920.20 KSA02349.1 - 0.047 13.7 40.7 0.28 11.1 29.1 3.5 1 1 1 2 2 2 0 Prefoldin subunit Spc7 PF08317.11 KSA02349.1 - 0.047 12.6 39.3 0.029 13.3 27.8 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein FapA PF03961.13 KSA02349.1 - 0.051 12.2 32.7 0.56 8.7 14.7 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A KLRAQ PF10205.9 KSA02349.1 - 0.07 13.4 29.4 1.4 9.2 9.8 2.4 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein ADIP PF11559.8 KSA02349.1 - 0.074 13.1 36.5 0.83 9.7 12.2 2.9 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding MIS13 PF08202.11 KSA02349.1 - 0.074 12.3 32.2 0.69 9.1 19.4 2.1 1 1 1 2 2 2 0 Mis12-Mtw1 protein family TPR_MLP1_2 PF07926.12 KSA02349.1 - 0.076 13.1 45.6 1.1 9.4 33.1 2.8 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4200 PF13863.6 KSA02349.1 - 0.077 13.4 41.7 1 9.8 22.3 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DUF3287 PF11690.8 KSA02349.1 - 0.079 12.7 10.1 0.55 10.0 1.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3287) DUF4201 PF13870.6 KSA02349.1 - 0.095 12.4 34.6 0.13 11.9 10.8 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) bZIP_2 PF07716.15 KSA02349.1 - 0.097 12.8 2.0 0.097 12.8 2.0 5.4 3 3 3 6 6 6 0 Basic region leucine zipper Alanine_zipper PF11839.8 KSA02349.1 - 0.11 12.8 10.5 5 7.6 0.8 3.9 2 1 2 4 4 4 0 Alanine-zipper, major outer membrane lipoprotein T2SSM PF04612.12 KSA02349.1 - 0.12 12.4 8.8 0.078 13.0 2.9 2.5 1 1 0 2 2 2 0 Type II secretion system (T2SS), protein M Prefoldin PF02996.17 KSA02349.1 - 0.13 12.2 34.7 0.079 12.9 3.4 4.0 1 1 3 4 4 4 0 Prefoldin subunit WXG100 PF06013.12 KSA02349.1 - 0.13 12.5 15.9 2.7 8.3 0.9 4.1 2 1 1 3 3 3 0 Proteins of 100 residues with WXG Rootletin PF15035.6 KSA02349.1 - 0.14 12.1 35.2 2.1 8.3 16.8 2.2 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion ERM PF00769.19 KSA02349.1 - 0.15 11.8 40.7 6.2 6.6 11.9 2.1 1 1 0 1 1 1 0 Ezrin/radixin/moesin family MscS_porin PF12795.7 KSA02349.1 - 0.16 11.5 34.7 0.11 12.0 17.8 2.0 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain CEP63 PF17045.5 KSA02349.1 - 0.16 11.8 32.7 0.36 10.7 32.7 1.5 1 1 0 1 1 1 0 Centrosomal protein of 63 kDa TMPIT PF07851.13 KSA02349.1 - 0.17 11.1 29.8 0.34 10.1 15.5 2.0 1 1 1 2 2 2 0 TMPIT-like protein DUF745 PF05335.13 KSA02349.1 - 0.17 11.6 24.2 0.53 10.0 6.7 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF745) EzrA PF06160.12 KSA02349.1 - 0.19 9.9 35.5 2.4 6.2 35.5 2.0 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA Snapin_Pallidin PF14712.6 KSA02349.1 - 0.21 12.0 25.4 0.16 12.4 5.7 3.2 1 1 1 3 3 3 0 Snapin/Pallidin APG17 PF04108.12 KSA02349.1 - 0.22 10.6 22.7 0.35 9.9 3.4 3.0 1 1 2 3 3 3 0 Autophagy protein Apg17 PI3K_P85_iSH2 PF16454.5 KSA02349.1 - 0.22 11.1 32.9 1.1 8.9 3.9 3.0 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain ABC_tran_CTD PF16326.5 KSA02349.1 - 0.22 11.8 39.9 0.074 13.3 10.2 3.5 1 1 2 3 3 3 0 ABC transporter C-terminal domain DUF3584 PF12128.8 KSA02349.1 - 0.24 8.9 34.0 0.74 7.3 34.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) HOOK PF05622.12 KSA02349.1 - 0.24 9.5 36.4 0.12 10.5 33.9 1.5 1 1 1 2 2 2 0 HOOK protein XhlA PF10779.9 KSA02349.1 - 0.3 11.3 36.7 0.25 11.6 3.1 4.2 2 2 3 5 5 5 0 Haemolysin XhlA NPV_P10 PF05531.12 KSA02349.1 - 0.41 11.1 17.1 0.83 10.2 0.7 3.7 1 1 4 5 5 5 0 Nucleopolyhedrovirus P10 protein Golgin_A5 PF09787.9 KSA02349.1 - 0.42 10.0 32.6 0.43 10.0 19.7 2.0 1 1 1 2 2 2 0 Golgin subfamily A member 5 SH3BP5 PF05276.14 KSA02349.1 - 0.45 10.3 25.8 2.2 8.0 14.8 2.0 1 1 1 2 2 2 0 SH3 domain-binding protein 5 (SH3BP5) SHE3 PF17078.5 KSA02349.1 - 0.47 10.1 34.8 4.3 7.0 15.1 3.1 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 CLZ PF16526.5 KSA02349.1 - 0.48 10.8 31.8 1.5 9.2 13.4 3.9 1 1 2 3 3 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Uds1 PF15456.6 KSA02349.1 - 0.53 10.5 29.1 0.25 11.5 22.1 2.8 1 1 0 2 2 2 0 Up-regulated During Septation DUF4407 PF14362.6 KSA02349.1 - 0.55 9.5 22.4 0.78 9.0 22.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ZapB PF06005.12 KSA02349.1 - 0.6 10.6 46.6 3.1 8.3 9.2 4.1 1 1 2 4 4 4 0 Cell division protein ZapB kleA_kleC PF17383.2 KSA02349.1 - 0.65 10.4 11.5 1.3 9.4 2.4 2.9 2 1 1 3 3 3 0 Uncharacterized KorC regulated protein A DUF4472 PF14739.6 KSA02349.1 - 0.68 10.7 31.4 1.4 9.7 6.8 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4472) bZIP_1 PF00170.21 KSA02349.1 - 0.71 10.0 38.7 0.099 12.8 3.8 5.1 1 1 3 4 4 4 0 bZIP transcription factor GOLGA2L5 PF15070.6 KSA02349.1 - 0.76 8.4 30.2 2.3 6.8 30.2 1.6 1 1 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 Occludin_ELL PF07303.13 KSA02349.1 - 0.8 10.5 25.3 8.4 7.2 7.5 3.0 1 1 2 3 3 3 0 Occludin homology domain DUF4795 PF16043.5 KSA02349.1 - 0.93 9.1 34.3 3.7 7.1 22.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) Fib_alpha PF08702.10 KSA02349.1 - 0.95 9.6 24.3 2.3 8.4 16.1 2.8 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family PspA_IM30 PF04012.12 KSA02349.1 - 1 8.9 31.4 0.096 12.2 12.3 3.0 1 1 1 2 2 2 0 PspA/IM30 family DUF16 PF01519.16 KSA02349.1 - 1.1 9.8 29.3 1.5 9.3 11.7 2.5 1 1 2 3 3 3 0 Protein of unknown function DUF16 UPF0242 PF06785.11 KSA02349.1 - 1.2 9.1 41.3 6.6 6.8 19.1 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Atg14 PF10186.9 KSA02349.1 - 1.3 8.1 31.7 1.2 8.2 15.7 2.0 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 FAP206 PF12018.8 KSA02349.1 - 1.7 8.1 18.0 1.9 7.9 1.6 2.0 1 1 1 2 2 2 0 Domain of unknown function KELK PF15796.5 KSA02349.1 - 1.7 9.2 39.1 0.13 12.7 5.7 3.7 1 1 3 4 4 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Ax_dynein_light PF10211.9 KSA02349.1 - 1.8 8.5 40.4 0.94 9.4 10.4 3.3 1 1 2 3 3 3 0 Axonemal dynein light chain Seryl_tRNA_N PF02403.22 KSA02349.1 - 2.3 8.5 35.2 3.4 7.9 12.2 2.7 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Phage_GPO PF05929.11 KSA02349.1 - 2.4 7.7 24.6 1.2 8.7 16.0 2.0 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase BLOC1_2 PF10046.9 KSA02349.1 - 2.5 8.5 32.2 4.6 7.6 8.8 3.6 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc24 PF08286.11 KSA02349.1 - 3 8.1 36.8 6.9 7.0 7.4 4.0 1 1 3 4 4 4 0 Spc24 subunit of Ndc80 Sulfatase_C PF14707.6 KSA02349.1 - 3.4 8.4 13.0 3.2 8.5 6.1 2.8 1 1 2 3 3 3 0 C-terminal region of aryl-sulfatase CENP-H PF05837.12 KSA02349.1 - 3.5 8.1 34.2 3.6 8.0 13.3 2.2 1 1 1 2 2 2 0 Centromere protein H (CENP-H) HAUS-augmin3 PF14932.6 KSA02349.1 - 3.8 7.0 35.0 0.5 9.9 26.3 2.0 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 RPW8 PF05659.11 KSA02349.1 - 4.2 7.1 17.4 0.91 9.2 8.4 2.8 1 1 2 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 KxDL PF10241.9 KSA02349.1 - 4.2 7.7 21.6 2 8.8 0.9 3.6 1 1 2 3 3 3 0 Uncharacterized conserved protein AAA_13 PF13166.6 KSA02349.1 - 4.7 5.7 32.7 23 3.5 32.7 1.9 1 1 0 1 1 1 0 AAA domain TMF_TATA_bd PF12325.8 KSA02349.1 - 5.5 7.3 37.9 1.9 8.8 5.3 3.0 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding MbeD_MobD PF04899.12 KSA02349.1 - 5.6 7.1 13.4 3.4 7.9 1.7 3.1 2 1 1 3 3 3 0 MbeD/MobD like HMMR_N PF15905.5 KSA02349.1 - 6 6.2 41.8 1.5 8.2 22.5 2.0 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal CALCOCO1 PF07888.11 KSA02349.1 - 6.1 5.6 35.5 40 2.9 35.5 1.9 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Swi5 PF07061.11 KSA02349.1 - 6.1 7.0 35.7 1.3 9.2 2.9 4.1 1 1 3 4 4 4 0 Swi5 DUF2203 PF09969.9 KSA02349.1 - 6.6 7.5 24.5 1.3 9.8 8.1 2.8 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) Lebercilin PF15619.6 KSA02349.1 - 7.9 6.1 39.4 19 4.9 13.6 2.2 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Sec20 PF03908.13 KSA02349.1 - 8.5 6.4 14.8 0.15 12.0 3.8 2.9 2 1 1 3 3 2 0 Sec20 DUF812 PF05667.11 KSA02349.1 - 9 5.0 37.3 8.8 5.1 4.8 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF812) HemX PF04375.14 KSA02349.1 - 9.1 5.5 30.0 7 5.8 11.0 2.8 1 1 2 3 3 3 0 HemX, putative uroporphyrinogen-III C-methyltransferase IFT57 PF10498.9 KSA02349.1 - 9.3 5.1 31.3 3.5 6.5 3.7 2.1 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 DUF948 PF06103.11 KSA02349.1 - 9.7 6.5 15.7 9.9 6.5 2.5 3.0 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) EOS1 PF12326.8 KSA02350.1 - 2.5e-42 144.7 21.4 2.2e-33 115.7 9.4 3.3 2 2 1 3 3 3 2 N-glycosylation protein Ribosomal_S13 PF00416.22 KSA02351.1 - 1.5e-18 67.4 0.8 2e-16 60.5 0.8 2.0 1 1 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 KSA02351.1 - 0.0094 14.8 0.0 0.01 14.6 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) End3 PF12761.7 KSA02352.1 - 1.2e-66 224.7 7.6 1.9e-66 224.1 7.6 1.3 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.7 KSA02352.1 - 8.4e-57 189.6 0.7 3.6e-55 184.3 0.5 2.5 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 KSA02352.1 - 4.8e-05 22.6 1.7 9.1e-05 21.7 0.2 2.2 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 KSA02352.1 - 0.0015 18.9 0.1 0.0015 18.9 0.1 2.8 4 0 0 4 4 4 1 EF-hand domain pair EF-hand_8 PF13833.6 KSA02352.1 - 0.0027 17.5 0.2 0.0063 16.3 0.2 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 KSA02352.1 - 0.007 15.8 0.4 0.24 11.0 0.1 2.6 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 KSA02352.1 - 0.072 13.1 1.1 0.18 11.8 0.2 2.2 2 0 0 2 2 2 0 EF-hand domain FlxA PF14282.6 KSA02352.1 - 5.5 7.0 9.6 20 5.3 8.6 2.2 1 1 1 2 2 2 0 FlxA-like protein Complex1_30kDa PF00329.19 KSA02353.1 - 2.6e-45 154.0 0.0 4.1e-45 153.3 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit Zn_clus PF00172.18 KSA02354.1 - 2.1e-05 24.5 9.0 3.6e-05 23.8 9.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Asp PF00026.23 KSA02355.1 - 4.4e-62 210.3 13.1 1.7e-53 182.1 9.3 2.3 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 KSA02355.1 - 1.1e-07 32.2 7.0 4.6e-05 23.7 6.5 3.3 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KSA02355.1 - 2.5e-06 28.0 0.4 1.4 9.6 0.0 4.2 4 0 0 4 4 4 3 Aspartyl protease gag-asp_proteas PF13975.6 KSA02355.1 - 1.7e-05 25.2 0.0 4.2 8.0 0.0 4.2 4 0 0 4 4 4 3 gag-polyprotein putative aspartyl protease TAF4 PF05236.14 KSA02355.1 - 0.006 16.4 0.3 0.01 15.6 0.3 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family MSP1a PF11670.8 KSA02355.1 - 0.021 14.1 0.1 0.043 13.1 0.1 1.4 1 0 0 1 1 1 0 Major surface protein 1a (MSP1a) zf-RING_2 PF13639.6 KSA02356.1 - 6.6e-11 42.4 4.7 7.2e-10 39.0 1.7 2.3 2 0 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 KSA02356.1 - 2.4e-07 30.5 1.0 2.4e-07 30.5 1.0 1.7 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KSA02356.1 - 4.1e-07 30.2 1.0 4.1e-07 30.2 1.0 1.8 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KSA02356.1 - 3.6e-06 26.9 4.4 2.6e-05 24.2 1.0 2.6 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KSA02356.1 - 8e-06 25.6 2.2 5.5e-05 22.9 0.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KSA02356.1 - 2e-05 24.4 3.5 2e-05 24.4 3.5 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KSA02356.1 - 4.4e-05 23.3 1.1 4.4e-05 23.3 1.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KSA02356.1 - 0.00011 22.0 2.6 0.0023 17.8 0.5 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KSA02356.1 - 0.0018 18.4 2.3 0.0018 18.4 2.3 1.7 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 KSA02356.1 - 0.0048 16.9 0.1 0.01 15.8 0.1 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger DUF1644 PF07800.12 KSA02356.1 - 0.019 15.0 0.8 0.064 13.3 0.8 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1644) zf-RING_11 PF17123.5 KSA02356.1 - 0.064 13.0 3.4 3.5 7.5 0.3 2.6 2 0 0 2 2 2 0 RING-like zinc finger FANCL_C PF11793.8 KSA02356.1 - 0.19 11.9 4.2 2.6 8.3 1.8 3.0 2 1 0 2 2 2 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 KSA02356.1 - 2.4 7.8 6.0 0.23 11.1 1.4 1.6 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-Nse PF11789.8 KSA02356.1 - 5.6 6.9 5.8 0.49 10.3 1.1 1.7 2 0 0 2 2 1 0 Zinc-finger of the MIZ type in Nse subunit Pro_isomerase PF00160.21 KSA02357.1 - 6.3e-41 140.3 0.3 9.2e-41 139.8 0.3 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.17 KSA02357.1 - 3.2e-05 23.7 4.6 0.0053 16.8 0.2 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KSA02357.1 - 0.03 14.5 8.2 0.22 11.8 0.1 4.3 3 2 2 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 KSA02357.1 - 0.042 13.7 6.3 0.13 12.2 0.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 KSA02357.1 - 0.08 12.6 0.1 0.23 11.2 0.0 1.9 2 0 0 2 2 2 0 TPR repeat SQS_PSY PF00494.19 KSA02358.1 - 4.3e-25 88.7 0.0 5.2e-25 88.4 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase Sec7 PF01369.20 KSA02359.1 - 1e-66 224.1 0.7 7.9e-66 221.2 0.1 2.8 3 0 0 3 3 3 1 Sec7 domain Sec7_N PF12783.7 KSA02359.1 - 2.4e-12 47.0 2.1 2.4e-12 47.0 2.1 3.1 4 0 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 KSA02359.1 - 7.2e-07 29.0 5.2 7.2e-07 29.0 5.2 4.6 5 0 0 5 5 5 1 Dimerisation and cyclophilin-binding domain of Mon2 MID_MedPIWI PF18296.1 KSA02359.1 - 2.8 7.7 8.3 4 7.1 2.1 2.7 2 0 0 2 2 2 0 MID domain of medPIWI PTPlike_phytase PF14566.6 KSA02359.1 - 9.7 6.3 7.3 30 4.7 7.3 1.8 1 0 0 1 1 1 0 Inositol hexakisphosphate OMPdecase PF00215.24 KSA02360.1 - 2.2e-77 259.7 0.0 2.5e-77 259.5 0.0 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Phage_GPD PF05954.11 KSA02360.1 - 0.22 10.8 0.0 0.35 10.1 0.0 1.2 1 0 0 1 1 1 0 Phage late control gene D protein (GPD) Mito_carr PF00153.27 KSA02361.1 - 5.3e-13 48.7 1.9 6.5e-09 35.6 0.2 3.2 3 0 0 3 3 3 2 Mitochondrial carrier protein GW PF13457.6 KSA02361.1 - 0.035 14.7 0.3 2.5 8.8 0.0 2.8 2 0 0 2 2 2 0 GW (Gly-Tryp) dipeptide domain SF3A3 PF16837.5 KSA02361.1 - 1.8 9.2 7.3 8.8 6.9 0.0 3.0 3 0 0 3 3 3 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 Vps26 PF03643.15 KSA02362.1 - 3.2e-116 387.2 0.1 3.6e-116 387.0 0.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 KSA02362.1 - 1e-07 32.1 0.9 0.0088 16.1 0.1 2.3 1 1 1 2 2 2 2 Arrestin (or S-antigen), N-terminal domain MG2 PF01835.19 KSA02362.1 - 0.057 13.9 0.0 0.31 11.5 0.0 2.2 1 0 0 1 1 1 0 MG2 domain Rgp1 PF08737.10 KSA02362.1 - 0.12 11.5 0.4 12 5.0 0.0 2.9 3 0 0 3 3 3 0 Rgp1 RasGEF PF00617.19 KSA02363.1 - 1.7e-56 191.2 2.2 5.7e-56 189.5 2.2 2.0 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KSA02363.1 - 2.7e-25 88.6 0.4 1.5e-24 86.2 0.1 2.5 2 0 0 2 2 2 1 RasGEF N-terminal motif SH3_1 PF00018.28 KSA02363.1 - 2.6e-14 52.5 0.1 6e-14 51.4 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KSA02363.1 - 2.3e-10 40.2 0.1 6.8e-10 38.7 0.1 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 KSA02363.1 - 6e-07 29.1 0.0 2e-06 27.4 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain TPR_MLP1_2 PF07926.12 KSA02364.1 - 0.00033 20.7 18.5 0.00033 20.7 18.5 11.1 4 2 6 11 11 11 3 TPR/MLP1/MLP2-like protein DUF948 PF06103.11 KSA02364.1 - 0.0013 18.9 1.8 0.0013 18.9 1.8 11.0 4 2 10 14 14 14 3 Bacterial protein of unknown function (DUF948) GAS PF13851.6 KSA02364.1 - 0.0032 16.8 22.8 0.0032 16.8 22.8 9.5 3 1 8 11 11 11 4 Growth-arrest specific micro-tubule binding T3SS_needle_E PF08988.10 KSA02364.1 - 0.034 14.3 0.9 0.034 14.3 0.9 6.5 7 1 1 8 8 8 0 Type III secretion system, cytoplasmic E component of needle BAH PF01426.18 KSA02365.1 - 2.7e-13 49.9 0.3 1.7e-12 47.2 0.0 2.7 2 0 0 2 2 2 1 BAH domain PHD PF00628.29 KSA02365.1 - 6e-13 48.5 48.1 6.5e-08 32.3 10.2 5.7 6 0 0 6 6 6 3 PHD-finger zf-HC5HC2H_2 PF13832.6 KSA02365.1 - 0.0016 18.6 28.4 0.009 16.2 2.8 6.0 5 1 1 6 6 6 2 PHD-zinc-finger like domain PHD_2 PF13831.6 KSA02365.1 - 0.0019 17.7 0.6 0.0019 17.7 0.6 5.3 5 0 0 5 5 5 1 PHD-finger zf-HC5HC2H PF13771.6 KSA02365.1 - 0.0069 16.6 3.1 0.0069 16.6 3.1 5.9 5 1 1 6 6 6 1 PHD-like zinc-binding domain CholecysA-Rec_N PF09193.10 KSA02365.1 - 4.8 7.3 6.1 10 6.2 0.1 3.9 5 0 0 5 5 5 0 Cholecystokinin A receptor, N-terminal mRNA_cap_enzyme PF01331.19 KSA02366.1 - 6.1e-57 192.6 0.0 9.2e-57 192.0 0.0 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 KSA02366.1 - 2e-33 115.2 0.1 4e-33 114.3 0.1 1.5 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 KSA02366.1 - 2.6e-06 27.2 0.0 0.021 14.5 0.0 2.3 1 1 1 2 2 2 2 ATP dependent DNA ligase domain RNA_ligase PF09414.10 KSA02366.1 - 0.017 15.5 0.0 0.026 14.8 0.0 1.4 1 0 0 1 1 1 0 RNA ligase Arrestin_N PF00339.29 KSA02367.1 - 3.5e-06 27.1 1.7 7.1e-05 22.9 0.0 2.7 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 KSA02367.1 - 2e-05 24.4 0.0 5.3e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Arrestin_N terminal like Arrestin_C PF02752.22 KSA02367.1 - 0.001 19.5 0.2 0.0048 17.3 0.0 2.3 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Prefoldin_2 PF01920.20 KSA02368.1 - 1.7e-18 66.5 14.6 1.9e-18 66.3 14.6 1.0 1 0 0 1 1 1 1 Prefoldin subunit HAUS2 PF15003.6 KSA02368.1 - 0.16 11.7 4.2 0.21 11.3 4.1 1.3 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 2 Med4 PF10018.9 KSA02368.1 - 0.48 10.1 6.9 0.053 13.2 1.4 1.9 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 PCRF PF03462.18 KSA02368.1 - 1.6 8.5 7.3 3.4 7.5 7.3 1.5 1 1 0 1 1 1 0 PCRF domain APG6_N PF17675.1 KSA02368.1 - 4.4 7.8 12.5 24 5.5 12.2 1.9 1 1 0 1 1 1 0 Apg6 coiled-coil region Osmo_CC PF08946.10 KSA02368.1 - 4.8 7.5 10.8 0.089 13.1 2.1 2.4 2 1 0 2 2 2 0 Osmosensory transporter coiled coil Arc_PepC_II PF06847.11 KSA02368.1 - 5.9 7.5 5.8 5.8 7.5 0.5 2.1 1 1 1 2 2 2 0 Archaeal Peptidase A24 C-terminus Type II Fib_alpha PF08702.10 KSA02368.1 - 8.8 6.5 9.1 17 5.6 1.1 2.1 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Acetyltransf_1 PF00583.25 KSA02369.1 - 1.6e-06 28.4 0.0 0.02 15.1 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 KSA02369.1 - 3.6e-05 23.9 0.3 0.0013 18.8 0.0 2.6 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KSA02369.1 - 5.6e-05 23.5 0.0 0.0011 19.4 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain DUF4973 PF16343.5 KSA02369.1 - 0.027 14.5 0.6 0.11 12.5 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4973) Acetyltransf_10 PF13673.7 KSA02369.1 - 0.052 13.5 0.0 0.48 10.4 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain DXPR_C PF13288.6 KSA02369.1 - 0.076 13.3 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 DXP reductoisomerase C-terminal domain motB PF17613.2 KSA02369.1 - 0.082 12.8 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Modifier of transcription Glutaredoxin PF00462.24 KSA02370.1 - 4.1e-18 65.4 0.0 5.8e-18 64.9 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.14 KSA02370.1 - 0.0012 19.2 0.0 0.0017 18.7 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_3 PF13192.6 KSA02370.1 - 0.0015 18.6 0.0 0.0024 17.9 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_2 PF13098.6 KSA02370.1 - 0.032 14.7 0.1 0.05 14.1 0.1 1.4 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_9 PF14595.6 KSA02370.1 - 0.04 13.7 0.1 0.057 13.2 0.1 1.2 1 1 0 1 1 1 0 Thioredoxin Glyco_transf_49 PF13896.6 KSA02370.1 - 0.096 12.0 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 Glycosyl-transferase for dystroglycan GST_N_3 PF13417.6 KSA02370.1 - 0.15 12.5 0.0 0.42 11.1 0.0 1.7 1 1 1 2 2 2 0 Glutathione S-transferase, N-terminal domain TraF PF13728.6 KSA02370.1 - 0.18 11.6 0.0 0.22 11.3 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein DSBA PF01323.20 KSA02370.1 - 0.29 10.9 0.6 15 5.2 0.0 2.1 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Homeobox_KN PF05920.11 KSA02372.1 - 1.3e-16 60.2 1.9 2.5e-16 59.3 1.9 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 KSA02372.1 - 0.00071 19.4 0.9 0.0014 18.5 0.9 1.5 1 0 0 1 1 1 1 Homeodomain Exo70 PF03081.15 KSA02373.1 - 2.2e-65 221.1 13.9 2.2e-65 221.1 13.9 2.0 2 0 0 2 2 2 1 Exo70 exocyst complex subunit NuiA PF07924.11 KSA02373.1 - 0.0095 16.3 0.3 2.7 8.4 0.0 3.5 2 1 1 3 3 3 1 Nuclease A inhibitor-like protein DUF4454 PF14628.6 KSA02373.1 - 0.061 13.2 0.1 0.15 11.9 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4454) DASH_Duo1 PF08651.10 KSA02373.1 - 0.18 11.6 0.2 0.18 11.6 0.2 4.0 3 1 1 4 4 4 0 DASH complex subunit Duo1 PBS_linker_poly PF00427.21 KSA02373.1 - 0.2 11.7 3.1 0.44 10.6 0.2 2.8 2 1 0 2 2 2 0 Phycobilisome Linker polypeptide RNA_lig_T4_1 PF09511.10 KSA02374.1 - 3.2e-76 256.0 0.2 9.4e-76 254.5 0.2 1.9 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.11 KSA02374.1 - 2.2e-70 236.1 3.3 4.6e-70 235.0 3.3 1.6 1 0 0 1 1 1 1 tRNA ligase kinase domain tRNA_lig_CPD PF08302.11 KSA02374.1 - 1e-44 152.9 0.9 2.1e-44 151.9 0.9 1.5 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain Barstar PF01337.18 KSA02374.1 - 0.0021 18.1 0.7 0.22 11.6 0.1 3.4 3 0 0 3 3 3 1 Barstar (barnase inhibitor) AAA_22 PF13401.6 KSA02374.1 - 0.0042 17.3 0.0 0.012 15.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF4879 PF16219.5 KSA02374.1 - 0.07 13.4 0.0 0.82 9.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4879) P2 PF07194.11 KSA02374.1 - 0.11 12.6 0.0 0.65 10.1 0.0 2.3 2 0 0 2 2 2 0 P2 response regulator binding domain OTCace PF00185.24 KSA02375.1 - 8.8e-50 168.8 0.8 1.6e-49 168.0 0.8 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 KSA02375.1 - 2e-41 141.5 1.7 4.6e-41 140.3 0.3 2.2 2 1 1 3 3 3 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain Lge1 PF11488.8 KSA02375.1 - 0.012 15.8 0.2 0.032 14.4 0.2 1.8 1 0 0 1 1 1 0 Transcriptional regulatory protein LGE1 HhH-GPD PF00730.25 KSA02376.1 - 4.3e-09 36.8 0.0 6.9e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Pox_LP_H2 PF03356.15 KSA02376.1 - 0.14 12.0 0.1 0.25 11.2 0.1 1.3 1 0 0 1 1 1 0 Viral late protein H2 Transthyretin PF00576.21 KSA02379.1 - 5.9e-34 117.1 0.0 7e-34 116.8 0.0 1.1 1 0 0 1 1 1 1 HIUase/Transthyretin family Stn1 PF10451.9 KSA02380.1 - 3.5e-17 62.2 0.0 6.4e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 Telomere regulation protein Stn1 PLU-1 PF08429.11 KSA02380.1 - 0.00028 20.2 0.1 0.00048 19.4 0.1 1.4 1 0 0 1 1 1 1 PLU-1-like protein 4HB PF17947.1 KSA02380.1 - 0.053 13.6 0.0 15 5.7 0.0 2.5 2 0 0 2 2 2 0 Four helical bundle domain putAbiC PF16872.5 KSA02380.1 - 1.6 9.4 6.3 7.8 7.3 0.1 3.7 4 0 0 4 4 4 0 Putative phage abortive infection protein Methyltransf_8 PF05148.15 KSA02381.1 - 1.6e-60 204.7 2.4 6.5e-30 104.6 0.0 3.4 2 1 1 3 3 3 2 Hypothetical methyltransferase Methyltransf_11 PF08241.12 KSA02381.1 - 3e-07 31.0 0.0 9.8e-07 29.3 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KSA02381.1 - 0.00024 21.7 0.0 0.0044 17.7 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KSA02381.1 - 0.0031 17.3 0.0 0.24 11.2 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KSA02381.1 - 0.1 12.1 0.0 0.75 9.3 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase small domain LCD1 PF09798.9 KSA02381.1 - 5.2 5.5 11.2 8.8 4.7 11.2 1.3 1 0 0 1 1 1 0 DNA damage checkpoint protein Presenilin PF01080.17 KSA02381.1 - 7.4 5.2 7.5 15 4.2 7.5 1.4 1 0 0 1 1 1 0 Presenilin WD40 PF00400.32 KSA02382.1 - 2.1e-06 28.4 6.4 0.025 15.5 0.1 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KSA02382.1 - 6.2e-06 26.4 0.1 0.00021 21.5 0.0 2.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KSA02382.1 - 0.026 13.8 0.1 0.13 11.5 0.0 2.0 2 0 0 2 2 2 0 WD40-like domain HECT PF00632.25 KSA02383.1 - 3.6e-94 315.7 0.0 5e-94 315.2 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 KSA02383.1 - 5.9e-33 112.6 23.4 4.5e-12 45.8 2.1 4.0 4 0 0 4 4 4 3 WW domain C2 PF00168.30 KSA02383.1 - 8.9e-19 67.7 0.4 2.4e-18 66.3 0.4 1.7 1 0 0 1 1 1 1 C2 domain Pkinase PF00069.25 KSA02385.1 - 5.2e-25 88.3 0.0 6.6e-25 88.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KSA02385.1 - 4.2e-11 42.6 0.0 6.3e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KSA02385.1 - 1.4e-08 34.0 0.1 2.2e-08 33.3 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KSA02385.1 - 0.0015 18.5 0.0 0.056 13.4 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family MRG PF05712.13 KSA02386.1 - 1.5e-42 145.2 0.4 2.5e-42 144.4 0.4 1.3 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 KSA02386.1 - 7.1e-10 38.6 0.2 1.7e-09 37.4 0.2 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Porin_1 PF00267.21 KSA02386.1 - 0.088 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Gram-negative porin Arginase PF00491.21 KSA02386.1 - 0.2 11.1 0.0 0.36 10.3 0.0 1.4 1 0 0 1 1 1 0 Arginase family RGI1 PF10843.8 KSA02388.1 - 1e-109 364.6 4.7 1.1e-109 364.5 4.7 1.0 1 0 0 1 1 1 1 Respiratory growth induced protein 1 FRG1 PF06229.12 KSA02389.1 - 0.0032 17.2 0.7 0.014 15.2 0.7 2.1 1 1 0 1 1 1 1 FRG1-like domain DUF4479 PF14794.6 KSA02389.1 - 0.13 12.1 0.4 0.13 12.1 0.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4479) PPV_E2_C PF00511.17 KSA02389.1 - 0.15 12.3 0.0 13 6.1 0.0 2.3 2 0 0 2 2 2 0 E2 (early) protein, C terminal Tim17 PF02466.19 KSA02390.1 - 7.9e-38 129.3 6.4 1e-37 128.9 6.4 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family CbtA PF09490.10 KSA02390.1 - 0.14 11.9 0.8 11 5.7 0.0 2.1 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtA) Chitin_synth_1 PF01644.17 KSA02392.1 - 4.5e-70 234.9 0.1 6.9e-70 234.2 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KSA02392.1 - 2.6e-24 85.0 0.0 6.4e-24 83.7 0.0 1.7 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KSA02392.1 - 5.2e-24 84.8 2.7 2e-16 59.7 0.0 3.2 2 1 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KSA02392.1 - 1.4e-07 31.6 0.0 1.4e-07 31.6 0.0 2.3 3 1 0 3 3 3 1 Glycosyl transferase family group 2 ATG19_autophagy PF12744.7 KSA02393.1 - 0.024 13.8 0.1 0.027 13.7 0.1 1.2 1 0 0 1 1 1 0 Autophagy protein Atg19, Atg8-binding Atg8 PF02991.16 KSA02394.1 - 5.1e-46 155.1 0.1 6.6e-46 154.8 0.1 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 KSA02394.1 - 1.6e-05 25.2 0.0 2.3e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Tantalus PF15386.6 KSA02394.1 - 0.094 12.8 0.4 0.31 11.2 0.0 2.1 3 0 0 3 3 3 0 Drosophila Tantalus-like FucT_N PF18025.1 KSA02394.1 - 0.11 12.9 0.1 0.2 12.2 0.1 1.5 1 1 0 1 1 1 0 Alpha-(1,3)-fucosyltransferase FucT N-terminal domain GatB_N PF02934.15 KSA02395.1 - 1.5e-93 313.2 0.0 1.9e-93 312.8 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 KSA02395.1 - 7.6e-26 90.8 1.4 1.4e-25 89.9 1.4 1.5 1 0 0 1 1 1 1 GatB domain DUF5470 PF17564.2 KSA02395.1 - 0.98 9.7 4.1 15 5.9 0.1 3.7 4 0 0 4 4 4 0 Family of unknown function (DUF5470) STE3 PF02076.15 KSA02396.1 - 2.3e-52 178.0 16.4 2.9e-52 177.7 16.4 1.1 1 0 0 1 1 1 1 Pheromone A receptor DUF3382 PF11862.8 KSA02396.1 - 0.012 15.9 0.7 0.012 15.9 0.7 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3382) ECSCR PF15820.5 KSA02396.1 - 1.9 8.4 4.0 0.72 9.7 0.1 2.3 1 1 1 2 2 2 0 Endothelial cell-specific chemotaxis regulator HEAT_EZ PF13513.6 KSA02397.1 - 3.9e-22 78.3 0.2 2.6e-09 37.4 0.1 7.4 6 0 0 6 6 6 3 HEAT-like repeat HEAT PF02985.22 KSA02397.1 - 1.2e-17 62.5 1.1 0.0053 16.9 0.1 9.6 10 0 0 10 10 9 3 HEAT repeat HEAT_2 PF13646.6 KSA02397.1 - 3.4e-13 49.8 1.8 0.044 14.2 0.0 6.8 6 2 1 7 7 6 4 HEAT repeats Cnd1 PF12717.7 KSA02397.1 - 9.5e-11 42.0 5.7 0.002 18.2 0.0 5.8 4 2 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 RIX1 PF08167.12 KSA02397.1 - 3.2e-09 36.8 0.4 0.0011 18.7 0.0 5.4 4 1 0 4 4 4 2 rRNA processing/ribosome biogenesis IBN_N PF03810.19 KSA02397.1 - 4.2e-09 36.2 5.8 3.5e-08 33.2 0.1 4.2 5 0 0 5 5 2 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.7 KSA02397.1 - 1.2e-08 35.4 3.2 1.8 9.2 0.0 6.9 5 1 1 6 6 6 3 Vacuolar 14 Fab1-binding region IFRD PF05004.13 KSA02397.1 - 1.2e-06 27.8 14.2 0.012 14.7 0.2 5.1 5 1 0 5 5 5 3 Interferon-related developmental regulator (IFRD) ParcG PF10274.9 KSA02397.1 - 1.9e-06 28.1 4.7 0.81 9.8 0.1 5.0 4 2 2 6 6 5 2 Parkin co-regulated protein RTP1_C1 PF10363.9 KSA02397.1 - 1.7e-05 24.9 2.6 2.6 8.2 0.1 5.0 5 1 0 5 5 4 2 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 KSA02397.1 - 5.8e-05 22.8 14.1 0.18 11.4 0.0 6.8 7 1 0 7 7 6 1 CLASP N terminal DUF3385 PF11865.8 KSA02397.1 - 0.00013 22.0 9.4 0.53 10.2 0.0 7.0 5 2 3 8 8 8 1 Domain of unknown function (DUF3385) Tti2 PF10521.9 KSA02397.1 - 0.0016 18.0 1.3 1.1 8.7 0.1 3.9 5 0 0 5 5 3 1 Tti2 family HEAT_PBS PF03130.16 KSA02397.1 - 0.0083 16.7 0.0 58 4.8 0.0 5.3 5 0 0 5 5 4 0 PBS lyase HEAT-like repeat MMS19_N PF14500.6 KSA02397.1 - 0.012 15.2 10.7 0.19 11.3 0.1 5.5 6 2 2 8 8 8 0 Dos2-interacting transcription regulator of RNA-Pol-II API5 PF05918.11 KSA02397.1 - 0.015 14.2 10.1 0.46 9.2 0.1 4.7 3 1 1 4 4 4 0 Apoptosis inhibitory protein 5 (API5) DUF5071 PF16804.5 KSA02397.1 - 0.26 11.6 7.4 4.1 7.7 0.1 5.2 3 1 2 5 5 5 0 Domain of unknown function (DUF5071) Bacillus_HBL PF05791.11 KSA02397.1 - 0.4 10.5 5.3 0.17 11.7 0.5 3.0 4 0 0 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) Arm PF00514.23 KSA02397.1 - 0.59 10.3 2.2 39 4.5 0.0 4.4 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Voldacs PF03517.13 KSA02397.1 - 1.6 8.8 5.9 1.3 9.1 0.1 3.2 3 0 0 3 3 3 0 Regulator of volume decrease after cellular swelling CelTOS PF18659.1 KSA02397.1 - 2.4 8.6 7.0 3 8.3 1.2 3.9 4 0 0 4 4 4 0 Cell-traversal protein for ookinetes and sporozoites CDC4_D PF16856.5 KSA02397.1 - 3.7 7.5 5.6 4.6 7.2 0.1 3.4 3 0 0 3 3 3 0 Cell division control protein 4 dimerisation domain DEAD PF00270.29 KSA02398.1 - 4.7e-43 147.0 1.6 4.7e-43 147.0 1.6 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KSA02398.1 - 8.3e-32 109.8 0.4 1e-30 106.3 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 KSA02398.1 - 2.5e-05 24.1 0.8 5e-05 23.1 0.2 1.8 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 KSA02398.1 - 0.00014 21.9 0.1 0.00028 20.9 0.1 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KSA02398.1 - 0.00021 21.7 0.2 0.00041 20.7 0.2 1.5 1 0 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 KSA02398.1 - 0.00049 20.0 0.0 0.00074 19.4 0.0 1.4 1 0 0 1 1 1 1 Helicase DUF4767 PF15983.5 KSA02398.1 - 0.0017 18.7 0.1 0.014 15.7 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4767) CMS1 PF14617.6 KSA02398.1 - 0.044 13.1 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Flavi_DEAD PF07652.14 KSA02398.1 - 0.059 13.4 0.5 0.37 10.8 0.1 2.6 2 1 0 2 2 2 0 Flavivirus DEAD domain PRK PF00485.18 KSA02399.1 - 2.5e-15 56.7 0.1 5.7e-14 52.3 0.1 2.1 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 KSA02399.1 - 4.3e-06 27.3 0.1 1.4e-05 25.7 0.1 1.8 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 KSA02399.1 - 0.00028 20.2 0.0 0.00054 19.3 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin CoaE PF01121.20 KSA02399.1 - 0.13 11.9 0.0 3.8 7.1 0.0 2.1 2 0 0 2 2 2 0 Dephospho-CoA kinase Nucleoporin_N PF08801.11 KSA02400.1 - 2.7e-144 481.1 11.6 4.4e-144 480.4 11.6 1.4 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 KSA02400.1 - 7.7e-115 384.9 10.5 1.1e-114 384.4 7.0 2.4 2 1 0 2 2 2 1 Non-repetitive/WGA-negative nucleoporin C-terminal Peptidase_M28 PF04389.17 KSA02401.1 - 2.7e-28 99.0 0.0 5.3e-28 98.1 0.0 1.4 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M20 PF01546.28 KSA02401.1 - 0.00014 21.7 0.0 0.00021 21.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 IGR PF09597.10 KSA02401.1 - 0.059 13.5 0.0 0.24 11.6 0.0 2.0 2 0 0 2 2 2 0 IGR protein motif SSB PF00436.25 KSA02402.1 - 3.6e-17 62.3 0.1 4.5e-17 62.0 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family Topo_Zn_Ribbon PF08272.11 KSA02402.1 - 0.12 12.0 0.1 4.6 7.0 0.0 2.4 2 0 0 2 2 2 0 Topoisomerase I zinc-ribbon-like MMS19_N PF14500.6 KSA02403.1 - 0.098 12.2 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Dos2-interacting transcription regulator of RNA-Pol-II DMRL_synthase PF00885.19 KSA02404.1 - 4.1e-23 81.8 0.0 4.3e-23 81.7 0.0 1.0 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase SecY PF00344.20 KSA02405.1 - 7.3e-44 150.2 15.1 8.9e-44 150.0 15.1 1.0 1 0 0 1 1 1 1 SecY translocase DUF5004 PF16395.5 KSA02405.1 - 0.2 11.7 0.3 2.3 8.2 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF5004) AA_permease_2 PF13520.6 KSA02406.1 - 2.2e-50 171.8 53.7 2.7e-50 171.5 53.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KSA02406.1 - 4.1e-21 75.1 48.2 5.3e-21 74.7 48.2 1.0 1 0 0 1 1 1 1 Amino acid permease LNS2 PF08235.13 KSA02407.1 - 2.2e-97 325.0 0.0 3.9e-97 324.2 0.0 1.4 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 KSA02407.1 - 2.8e-40 136.4 0.0 8.4e-40 134.9 0.0 1.9 1 0 0 1 1 1 1 lipin, N-terminal conserved region Hydrolase_6 PF13344.6 KSA02407.1 - 0.042 13.9 0.1 0.18 12.0 0.0 2.1 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase DUF3589 PF12141.8 KSA02408.1 - 1.6e-196 653.6 2.5 2e-196 653.4 2.5 1.1 1 0 0 1 1 1 1 Beta-mannosyltransferases DUF3589 PF12141.8 KSA02409.1 - 2.2e-200 666.4 3.5 2.7e-200 666.2 3.5 1.1 1 0 0 1 1 1 1 Beta-mannosyltransferases DUF777 PF05606.11 KSA02409.1 - 0.037 13.8 0.1 0.12 12.1 0.1 1.8 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF777) HUN PF08729.10 KSA02409.1 - 3 7.9 10.3 0.41 10.7 3.9 2.8 3 0 0 3 3 3 0 HPC2 and ubinuclein domain RRM_1 PF00076.22 KSA02412.1 - 4.7e-12 45.6 0.1 3.4e-08 33.2 0.1 2.7 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 KSA02412.1 - 0.0039 17.2 0.1 0.0073 16.4 0.1 1.5 2 0 0 2 2 2 1 Limkain b1 YflT PF11181.8 KSA02412.1 - 0.0097 16.4 0.1 0.014 15.9 0.1 1.3 1 0 0 1 1 1 1 Heat induced stress protein YflT SET_assoc PF11767.8 KSA02412.1 - 0.027 14.1 0.0 0.45 10.2 0.0 2.2 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated RRM_5 PF13893.6 KSA02412.1 - 0.099 12.2 0.0 0.18 11.4 0.0 1.5 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SPOR PF05036.13 KSA02412.1 - 0.1 13.0 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 Sporulation related domain DUF3110 PF11360.8 KSA02412.1 - 0.14 12.4 0.1 0.29 11.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3110) RRM_occluded PF16842.5 KSA02412.1 - 0.14 12.0 0.0 2.5 8.0 0.0 2.2 2 1 0 2 2 2 0 Occluded RNA-recognition motif Ribosomal_L5e PF17144.4 KSA02413.1 - 3e-80 267.9 0.0 6.8e-80 266.8 0.0 1.6 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 KSA02413.1 - 6.1e-31 107.2 9.2 6.1e-31 107.2 9.2 1.9 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Ribosomal_L18p PF00861.22 KSA02413.1 - 0.0019 18.6 0.4 0.0035 17.7 0.0 1.6 2 0 0 2 2 2 1 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast DAG_kinase_N PF14513.6 KSA02413.1 - 0.003 17.8 3.1 0.0057 16.9 3.1 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase N-terminus Colicin_immun PF09204.10 KSA02413.1 - 0.032 14.8 1.6 0.084 13.4 0.4 2.3 2 1 0 2 2 2 0 Bacterial self-protective colicin-like immunity Thr_synth_N PF14821.6 KSA02413.1 - 0.035 14.3 1.2 0.5 10.6 0.0 2.9 3 1 0 3 3 3 0 Threonine synthase N terminus NAC PF01849.18 KSA02413.1 - 0.036 14.0 0.0 0.075 13.0 0.0 1.4 1 0 0 1 1 1 0 NAC domain DUF1160 PF06648.11 KSA02413.1 - 0.12 12.4 0.1 0.29 11.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1160) NifU_N PF01592.16 KSA02415.1 - 4.7e-58 194.9 0.1 5.9e-58 194.6 0.1 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain TSCPD PF12637.7 KSA02415.1 - 0.011 15.9 0.1 0.02 15.1 0.1 1.3 1 0 0 1 1 1 0 TSCPD domain DUF1691 PF07950.11 KSA02416.1 - 1.1e-21 77.5 1.9 2.9e-12 47.3 0.2 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) Rho_N PF07498.12 KSA02416.1 - 0.0081 16.1 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 Rho termination factor, N-terminal domain Sdh_cyt PF01127.22 KSA02416.1 - 0.25 11.4 4.1 6.9 6.7 0.3 2.3 2 0 0 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit V-SNARE_C PF12352.8 KSA02417.1 - 1.8e-08 34.5 4.4 3.2e-08 33.7 0.2 2.6 2 1 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus DUF349 PF03993.12 KSA02417.1 - 0.02 15.1 0.7 0.02 15.1 0.7 1.9 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) DUF2996 PF11210.8 KSA02417.1 - 0.044 14.2 0.1 0.073 13.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2996) Syntaxin-6_N PF09177.11 KSA02417.1 - 1.9 9.1 11.9 0.46 11.1 7.6 2.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Evr1_Alr PF04777.13 KSA02418.1 - 2.1e-27 95.5 0.1 3.8e-27 94.7 0.1 1.4 1 0 0 1 1 1 1 Erv1 / Alr family APOBEC1 PF18769.1 KSA02418.1 - 0.12 12.6 0.1 0.28 11.5 0.0 1.6 1 1 0 1 1 1 0 APOBEC1 DUF3844 PF12955.7 KSA02419.1 - 1.3e-30 105.6 6.5 2.1e-30 105.0 6.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) SlpA PF03217.14 KSA02419.1 - 0.18 12.4 1.3 0.59 10.8 0.1 2.6 2 0 0 2 2 2 0 Surface later protein A domain Cyclin_N PF00134.23 KSA02421.1 - 8.9e-46 154.8 0.3 1.9e-45 153.7 0.3 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KSA02421.1 - 1.3e-37 128.5 0.1 3.4e-37 127.1 0.1 1.7 1 0 0 1 1 1 1 Cyclin, C-terminal domain DNA_pol_phi PF04931.13 KSA02421.1 - 4.6 5.2 16.0 9.2 4.2 16.0 1.4 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 KSA02421.1 - 5.3 6.3 12.5 10 5.3 12.5 1.4 1 0 0 1 1 1 0 NOA36 protein MAM33 PF02330.16 KSA02422.1 - 3.6e-49 167.6 7.6 4.4e-49 167.3 7.6 1.1 1 0 0 1 1 1 1 Mitochondrial glycoprotein Ribosomal_60s PF00428.19 KSA02423.1 - 2.8e-22 79.1 16.0 3.4e-22 78.8 16.0 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Apolipoprotein PF01442.18 KSA02425.1 - 0.00022 21.2 2.6 0.68 9.8 0.0 2.9 3 1 0 3 3 3 2 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 KSA02425.1 - 0.015 15.3 5.0 1.9 8.5 1.0 3.7 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Nbl1_Borealin_N PF10444.9 KSA02425.1 - 0.018 14.7 1.7 0.079 12.6 0.4 2.7 3 0 0 3 3 3 0 Nbl1 / Borealin N terminal Cor1 PF04803.12 KSA02425.1 - 0.018 15.3 13.8 0.02 15.1 9.3 2.7 1 1 1 2 2 2 0 Cor1/Xlr/Xmr conserved region DUF5446 PF17522.2 KSA02425.1 - 0.52 10.5 7.3 3.3 7.9 0.4 3.5 2 1 1 3 3 3 0 Family of unknown function (DUF5446) DUF883 PF05957.13 KSA02425.1 - 0.95 10.1 6.0 14 6.4 0.1 3.8 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF883) DNA_repr_REX1B PF14966.6 KSA02425.1 - 1.3 9.8 7.7 27 5.5 4.8 3.7 2 1 0 2 2 2 0 DNA repair REX1-B Remorin_C PF03763.13 KSA02425.1 - 7.6 6.5 7.7 1.6 8.6 3.1 2.4 2 1 0 2 2 2 0 Remorin, C-terminal region YscO-like PF16789.5 KSA02427.1 - 0.052 13.6 0.1 0.052 13.6 0.1 2.2 2 0 0 2 2 2 0 YscO-like protein DUF3599 PF12206.8 KSA02427.1 - 0.13 12.6 2.1 2.4 8.6 0.2 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF3599) FGGY_C PF02782.16 KSA02428.1 - 7.4e-70 234.7 0.2 9.4e-70 234.4 0.2 1.1 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KSA02428.1 - 4.1e-07 29.8 0.0 7.5e-06 25.7 0.0 2.3 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_N PF00370.21 KSA02429.1 - 4.1e-34 118.2 0.7 3.1e-26 92.4 0.1 2.0 1 1 1 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain UDPGP PF01704.18 KSA02430.1 - 4.6e-48 163.9 0.0 5.9e-48 163.5 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 KSA02430.1 - 0.18 12.2 0.1 0.31 11.4 0.1 1.3 1 0 0 1 1 1 0 MobA-like NTP transferase domain Recep_L_domain PF01030.24 KSA02431.1 - 7.3e-11 42.2 9.8 0.0028 17.8 0.3 4.4 1 1 3 4 4 4 4 Receptor L domain SCVP PF17619.2 KSA02431.1 - 0.00087 20.1 1.5 0.22 12.4 0.2 2.7 2 0 0 2 2 2 1 Secreted clade V proteins CooC_C PF15976.5 KSA02431.1 - 0.031 14.3 0.0 0.12 12.5 0.0 2.1 1 0 0 1 1 1 0 CS1-pili formation C-terminal Phage_TAC_7 PF10109.9 KSA02431.1 - 0.032 14.3 0.0 1.5 9.0 0.0 2.8 2 1 0 2 2 2 0 Phage tail assembly chaperone proteins, E, or 41 or 14 LRR_9 PF14580.6 KSA02431.1 - 0.078 12.5 1.2 0.16 11.5 0.5 1.9 1 1 1 2 2 2 0 Leucine-rich repeat Pheromone PF08015.11 KSA02431.1 - 0.29 12.2 9.4 0.23 12.5 3.4 3.1 2 1 0 2 2 2 0 Fungal mating-type pheromone Macoilin PF09726.9 KSA02431.1 - 0.32 9.5 11.0 0.45 9.0 11.0 1.2 1 0 0 1 1 1 0 Macoilin family MID_MedPIWI PF18296.1 KSA02431.1 - 0.51 10.1 8.2 1 9.1 8.2 1.4 1 0 0 1 1 1 0 MID domain of medPIWI SR-25 PF10500.9 KSA02431.1 - 8 6.0 33.1 20 4.7 33.1 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PH PF00169.29 KSA02432.1 - 4.7e-10 39.9 0.6 2.6e-09 37.5 0.0 2.8 2 0 0 2 2 2 1 PH domain Fip1 PF05182.13 KSA02433.1 - 7.3e-23 79.8 1.1 1.2e-22 79.1 1.1 1.4 1 0 0 1 1 1 1 Fip1 motif CSRNP_N PF16019.5 KSA02433.1 - 0.6 10.0 3.9 0.86 9.5 3.9 1.3 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus CDC27 PF09507.10 KSA02433.1 - 1.3 8.4 16.2 2.1 7.6 16.2 1.4 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 PPL5 PF18168.1 KSA02433.1 - 2.4 7.4 8.4 3.3 6.9 8.4 1.2 1 0 0 1 1 1 0 Prim-pol family 5 SDA1 PF05285.12 KSA02433.1 - 2.5 7.4 21.8 3.3 7.0 21.8 1.1 1 0 0 1 1 1 0 SDA1 Pox_Ag35 PF03286.14 KSA02433.1 - 3.4 7.4 14.3 4.9 6.9 14.3 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein eIF-5_eIF-2B PF01873.17 KSA02434.1 - 2.6e-37 127.3 0.1 4.6e-37 126.5 0.1 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 KSA02434.1 - 3e-24 85.0 10.7 7.5e-24 83.7 0.1 3.3 3 0 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon Nudix_N_2 PF14803.6 KSA02434.1 - 0.02 14.8 1.9 0.04 13.8 1.9 1.4 1 0 0 1 1 1 0 Nudix N-terminal Zn-ribbon_8 PF09723.10 KSA02434.1 - 0.22 11.6 0.8 0.51 10.5 0.8 1.6 1 0 0 1 1 1 0 Zinc ribbon domain CagY_I PF14585.6 KSA02434.1 - 0.43 10.7 2.6 37 4.5 0.2 3.2 3 0 0 3 3 3 0 CagY type 1 repeat PCI PF01399.27 KSA02435.1 - 6.5e-15 55.5 1.2 1.9e-14 54.1 1.2 1.8 1 0 0 1 1 1 1 PCI domain Imm49 PF15575.6 KSA02435.1 - 0.067 13.0 0.1 0.23 11.2 0.1 1.7 1 1 0 1 1 1 0 Immunity protein 49 TPR_1 PF00515.28 KSA02435.1 - 0.1 12.5 0.1 4.3 7.3 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat PUF PF00806.19 KSA02436.1 - 1.4e-24 84.4 7.2 8e-06 25.3 0.0 7.0 6 0 0 6 6 6 6 Pumilio-family RNA binding repeat TFIIA PF03153.13 KSA02436.1 - 7.5 6.4 55.9 1.1 9.2 28.6 2.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit LRR_4 PF12799.7 KSA02437.1 - 1.6e-13 50.5 15.0 0.24 11.9 0.2 8.2 5 2 3 8 8 8 6 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KSA02437.1 - 2.4e-10 40.1 0.5 5.3e-10 39.0 0.5 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KSA02437.1 - 5.7e-05 22.9 0.7 0.00022 21.0 0.7 2.1 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KSA02437.1 - 0.0027 17.6 0.0 0.0086 16.0 0.0 1.9 1 0 0 1 1 1 1 F-box PRANC PF09372.10 KSA02437.1 - 0.0051 17.1 4.6 0.0061 16.8 1.8 2.5 2 0 0 2 2 2 1 PRANC domain LcrV PF04792.12 KSA02437.1 - 0.0082 15.5 1.0 0.11 11.7 0.1 2.8 3 0 0 3 3 3 1 V antigen (LcrV) protein RNA_pol_Rpb5_N PF03871.14 KSA02437.1 - 0.14 12.8 0.0 0.41 11.3 0.0 1.9 1 0 0 1 1 1 0 RNA polymerase Rpb5, N-terminal domain Ribosomal_L37ae PF01780.19 KSA02439.1 - 7e-39 131.8 8.9 7.9e-39 131.6 8.9 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-RING_13 PF17977.1 KSA02439.1 - 0.0054 16.8 2.1 0.0072 16.4 2.1 1.2 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-H2C2_2 PF13465.6 KSA02439.1 - 0.0054 17.1 0.5 1.6 9.3 0.1 2.3 2 0 0 2 2 2 2 Zinc-finger double domain Zn_Tnp_IS1595 PF12760.7 KSA02439.1 - 0.006 16.5 4.3 0.01 15.8 4.3 1.4 1 0 0 1 1 1 1 Transposase zinc-ribbon domain CarbpepA_inh PF02977.15 KSA02439.1 - 0.073 12.9 3.1 0.11 12.3 0.7 2.1 1 1 1 2 2 2 0 Carboxypeptidase A inhibitor C1_2 PF03107.16 KSA02439.1 - 0.22 11.8 2.2 1.6 9.1 2.3 1.9 1 1 1 2 2 2 0 C1 domain zf-C4_ClpX PF06689.13 KSA02439.1 - 2.6 8.0 4.8 8 6.4 4.8 1.9 1 1 0 1 1 1 0 ClpX C4-type zinc finger ESCRT-II PF05871.12 KSA02440.1 - 4e-41 140.6 0.0 4.9e-41 140.2 0.0 1.1 1 0 0 1 1 1 1 ESCRT-II complex subunit CTP_synth_N PF06418.14 KSA02441.1 - 1.7e-121 404.5 0.7 3.3e-121 403.6 0.3 1.6 2 0 0 2 2 2 1 CTP synthase N-terminus GATase PF00117.28 KSA02441.1 - 2.3e-54 184.0 0.0 3.6e-54 183.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KSA02441.1 - 1.8e-05 24.6 0.0 6.6e-05 22.8 0.0 2.0 1 1 0 1 1 1 1 Peptidase C26 TPR_1 PF00515.28 KSA02442.1 - 1.9e-05 24.3 0.1 7.6e-05 22.4 0.1 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 KSA02442.1 - 2.8e-05 23.9 0.0 0.00035 20.5 0.2 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KSA02442.1 - 0.0001 22.8 0.1 0.023 15.2 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KSA02442.1 - 0.00092 19.2 1.7 0.019 15.2 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 KSA02442.1 - 0.0028 17.9 1.2 0.067 13.6 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 KSA02442.1 - 0.0036 17.4 0.0 0.008 16.3 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.6 KSA02442.1 - 0.014 16.0 1.0 55 4.7 0.0 4.7 5 1 0 5 5 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 KSA02442.1 - 0.037 13.7 1.1 0.12 12.1 0.9 2.1 1 1 1 2 2 2 0 TPR repeat TPR_20 PF14561.6 KSA02442.1 - 0.045 14.1 0.0 0.5 10.7 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 KSA02442.1 - 0.051 13.6 0.1 1.3 9.2 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 KSA02442.1 - 0.062 14.0 0.0 0.54 10.9 0.0 2.4 2 1 1 3 3 3 0 Tetratricopeptide repeat Tyosinase_C PF18132.1 KSA02442.1 - 0.086 13.5 0.0 0.15 12.7 0.0 1.5 1 0 0 1 1 1 0 Tyosinase C-terminal domain CENP-H PF05837.12 KSA02443.1 - 0.066 13.6 7.4 0.067 13.6 1.2 2.9 2 1 0 2 2 2 0 Centromere protein H (CENP-H) Tweety PF04906.13 KSA02443.1 - 0.44 9.2 5.0 0.16 10.6 1.1 1.9 2 0 0 2 2 2 0 Tweety GlutR_dimer PF00745.20 KSA02443.1 - 0.48 10.9 3.8 1.6 9.3 0.9 2.5 2 0 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain Sod_Fe_C PF02777.18 KSA02444.1 - 6.6e-18 64.8 0.0 2.9e-16 59.5 0.0 2.4 1 1 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain TIP41 PF04176.13 KSA02445.1 - 1.8e-69 232.7 0.1 2.9e-69 232.0 0.1 1.3 1 0 0 1 1 1 1 TIP41-like family GDPD PF03009.17 KSA02446.1 - 4.7e-74 249.4 0.0 3e-73 246.8 0.0 2.3 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.7 KSA02446.1 - 5.5e-24 84.6 0.8 1.9e-06 28.4 0.0 5.0 3 1 2 5 5 5 3 Ankyrin repeats (3 copies) SPX PF03105.19 KSA02446.1 - 1.1e-15 58.4 26.6 4.1e-11 43.4 0.4 4.8 3 1 2 5 5 5 3 SPX domain Ank_3 PF13606.6 KSA02446.1 - 3.9e-13 48.3 5.6 0.0095 16.4 0.0 6.7 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 KSA02446.1 - 4.3e-13 49.2 0.1 0.0058 16.9 0.1 5.6 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 KSA02446.1 - 7.4e-13 48.3 0.2 0.038 14.4 0.0 5.4 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 KSA02446.1 - 1.1e-12 48.2 1.7 0.017 15.7 0.0 5.6 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Sec34 PF04136.15 KSA02446.1 - 2.3 8.1 8.3 0.3 11.0 1.1 2.7 2 0 0 2 2 2 0 Sec34-like family Arginase PF00491.21 KSA02447.1 - 2.1e-48 165.3 0.0 2.3e-48 165.1 0.0 1.0 1 0 0 1 1 1 1 Arginase family ABC_tran PF00005.27 KSA02448.1 - 1e-37 129.7 0.3 5.3e-29 101.5 0.0 2.8 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KSA02448.1 - 1.2e-34 120.2 27.2 1.7e-34 119.8 27.2 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 KSA02448.1 - 1.2e-06 28.1 3.2 0.0074 15.7 0.2 3.3 2 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KSA02448.1 - 0.028 14.9 0.4 0.086 13.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain ABC_membrane PF00664.23 KSA02449.1 - 4.3e-30 105.3 15.4 6.5e-30 104.7 15.4 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KSA02449.1 - 8.7e-06 26.3 0.3 2.2e-05 25.0 0.3 1.7 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 KSA02449.1 - 0.0026 17.5 0.4 0.041 13.6 0.1 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.6 KSA02449.1 - 0.027 15.0 0.4 0.065 13.7 0.4 1.6 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 KSA02449.1 - 0.038 13.1 0.1 0.066 12.3 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_18 PF13238.6 KSA02449.1 - 0.042 14.4 0.5 0.11 13.0 0.1 1.9 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 KSA02449.1 - 0.092 12.0 0.1 0.21 10.8 0.1 1.5 1 0 0 1 1 1 0 KAP family P-loop domain SMC_N PF02463.19 KSA02449.1 - 0.83 9.0 2.2 0.56 9.6 0.2 1.7 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Aminotran_3 PF00202.21 KSA02450.1 - 2.1e-125 418.6 0.0 2.4e-125 418.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 KSA02450.1 - 0.0026 17.1 0.0 0.0038 16.6 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase AAA_26 PF13500.6 KSA02451.1 - 4e-50 170.4 0.0 4.8e-50 170.1 0.0 1.0 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 KSA02451.1 - 0.006 16.6 1.0 0.072 13.2 1.0 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain DUF1611 PF07755.11 KSA02451.1 - 0.07 12.4 0.2 4.1 6.6 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF1611_C) P-loop domain AA_permease_2 PF13520.6 KSA02452.1 - 1.5e-45 155.8 49.1 1.9e-45 155.5 49.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KSA02452.1 - 2.7e-13 49.3 42.2 3.7e-13 48.9 42.2 1.0 1 0 0 1 1 1 1 Amino acid permease FixQ PF05545.11 KSA02452.1 - 2.3 8.3 4.7 0.77 9.8 0.4 2.5 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ Globin PF00042.22 KSA02453.1 - 3e-10 40.6 0.0 6e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 Globin FAD_binding_6 PF00970.24 KSA02453.1 - 4.1e-10 39.9 0.0 7.4e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KSA02453.1 - 2.2e-08 34.7 0.0 1.8e-07 31.8 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Phage_HK97_TLTM PF06120.11 KSA02453.1 - 0.063 12.5 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Tail length tape measure protein Glyco_hydro_59 PF02057.15 KSA02453.1 - 0.13 11.5 0.1 0.21 10.8 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 59 DUF3589 PF12141.8 KSA02454.1 - 2.5e-91 306.7 0.0 4.6e-53 180.5 0.0 2.1 1 1 1 2 2 2 2 Beta-mannosyltransferases Glyco_hydro_2_C PF02836.17 KSA02455.1 - 3e-99 332.0 1.0 4.3e-99 331.5 0.1 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.17 KSA02455.1 - 1.7e-52 178.5 0.0 2.8e-52 177.8 0.0 1.4 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.18 KSA02455.1 - 4.1e-40 137.4 1.0 2e-39 135.2 0.2 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain DUF4981 PF16353.5 KSA02455.1 - 1.7e-16 60.5 0.1 4.5e-16 59.1 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function(DUF4981) Glyco_hydro_2 PF00703.21 KSA02455.1 - 3.7e-11 43.7 0.0 1.3e-10 41.9 0.0 2.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Sugar_tr PF00083.24 KSA02456.1 - 3.2e-98 329.6 22.5 3.6e-98 329.4 22.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KSA02456.1 - 6.8e-32 110.8 23.7 9.3e-32 110.3 20.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily PhyH PF05721.13 KSA02457.1 - 1.9e-23 83.8 0.0 2.5e-23 83.5 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) MFS_1 PF07690.16 KSA02458.1 - 4.9e-34 117.8 23.3 1.4e-32 113.0 23.8 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily MgtC PF02308.16 KSA02458.1 - 0.016 15.6 2.1 0.016 15.6 2.1 2.7 2 0 0 2 2 2 0 MgtC family G-patch_2 PF12656.7 KSA02458.1 - 0.2 11.8 0.2 0.6 10.2 0.0 1.8 2 0 0 2 2 2 0 G-patch domain DUF3302 PF11742.8 KSA02458.1 - 0.75 10.0 7.1 44 4.3 0.0 4.4 4 0 0 4 4 4 0 Protein of unknown function (DUF3302) AA_permease_2 PF13520.6 KSA02459.1 - 9.2e-60 202.6 52.2 1.1e-59 202.3 52.2 1.1 1 0 0 1 1 1 1 Amino acid permease PNTB PF02233.16 KSA02459.1 - 1.9 7.3 10.1 1.5 7.7 0.5 2.4 2 1 0 2 2 2 0 NAD(P) transhydrogenase beta subunit AAA PF00004.29 KSA02460.1 - 6.6e-46 156.0 0.1 2.3e-45 154.3 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KSA02460.1 - 2.7e-09 36.8 0.2 1.1e-08 34.9 0.0 2.1 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 KSA02460.1 - 6.3e-09 36.2 0.0 1.3e-08 35.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KSA02460.1 - 2e-08 34.8 0.1 2.6e-05 24.7 0.0 3.1 1 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 KSA02460.1 - 2.3e-07 30.9 0.1 9.7e-07 28.9 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KSA02460.1 - 6.8e-05 23.2 0.6 0.0068 16.7 0.0 2.7 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.13 KSA02460.1 - 8.3e-05 21.9 0.0 0.00015 21.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 KSA02460.1 - 0.00025 21.1 0.1 0.0009 19.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 KSA02460.1 - 0.00038 20.2 0.0 0.0012 18.6 0.0 1.8 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_lid_3 PF17862.1 KSA02460.1 - 0.00072 19.3 0.0 0.002 17.9 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain NTPase_1 PF03266.15 KSA02460.1 - 0.0014 18.6 0.0 0.0069 16.3 0.0 2.1 2 0 0 2 2 2 1 NTPase AAA_18 PF13238.6 KSA02460.1 - 0.0017 18.9 0.0 0.011 16.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KSA02460.1 - 0.0017 17.9 0.1 0.012 15.2 0.1 2.1 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_33 PF13671.6 KSA02460.1 - 0.0031 17.7 0.0 0.0069 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 KSA02460.1 - 0.0048 16.7 0.0 0.023 14.5 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KSA02460.1 - 0.0051 17.2 0.0 0.011 16.0 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_30 PF13604.6 KSA02460.1 - 0.0056 16.4 0.2 0.023 14.4 0.0 2.3 3 1 0 3 3 2 1 AAA domain TsaE PF02367.17 KSA02460.1 - 0.0059 16.6 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE TniB PF05621.11 KSA02460.1 - 0.0066 15.9 0.0 0.53 9.7 0.0 2.4 2 0 0 2 2 2 1 Bacterial TniB protein TIP49 PF06068.13 KSA02460.1 - 0.0078 15.4 0.6 0.021 14.1 0.0 1.9 2 0 0 2 2 2 1 TIP49 P-loop domain Mg_chelatase PF01078.21 KSA02460.1 - 0.0094 15.3 0.1 0.02 14.3 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 KSA02460.1 - 0.01 15.6 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KSA02460.1 - 0.011 15.7 0.2 0.13 12.2 0.0 2.3 2 0 0 2 2 2 0 NACHT domain Sigma54_activat PF00158.26 KSA02460.1 - 0.011 15.5 0.1 0.14 11.9 0.0 2.4 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_19 PF13245.6 KSA02460.1 - 0.011 16.0 0.0 0.45 10.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 KSA02460.1 - 0.017 14.9 0.2 0.12 12.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KSA02460.1 - 0.018 15.3 0.0 0.036 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KSA02460.1 - 0.024 14.4 0.0 0.053 13.3 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein ATPase_2 PF01637.18 KSA02460.1 - 0.05 13.5 2.0 0.28 11.1 0.1 2.8 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea Zeta_toxin PF06414.12 KSA02460.1 - 0.083 12.2 0.0 0.17 11.1 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.27 KSA02460.1 - 0.14 12.7 0.1 0.35 11.4 0.0 2.0 2 1 0 2 2 1 0 ABC transporter AAA_25 PF13481.6 KSA02460.1 - 0.25 10.9 2.6 0.4 10.2 0.1 2.4 2 1 0 3 3 3 0 AAA domain Glyco_transf_22 PF03901.17 KSA02461.1 - 7.6e-64 216.5 25.4 9.5e-64 216.1 25.4 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF2569 PF10754.9 KSA02461.1 - 4.1 7.8 13.4 0.49 10.8 7.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2569) Utp12 PF04003.12 KSA02462.1 - 2.6e-23 82.4 2.0 5e-23 81.5 2.0 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family RAB3GAP2_N PF14655.6 KSA02462.1 - 0.0012 18.3 0.0 0.0026 17.1 0.0 1.5 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF4888 PF16229.5 KSA02462.1 - 0.015 15.3 0.3 0.047 13.7 0.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4888) ANAPC4_WD40 PF12894.7 KSA02462.1 - 0.032 14.5 0.0 1.4 9.3 0.0 3.2 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain CBFD_NFYB_HMF PF00808.23 KSA02463.1 - 1.9e-11 44.0 2.7 1.9e-11 44.0 2.7 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T_C PF15511.6 KSA02463.1 - 0.042 14.0 0.1 0.068 13.3 0.1 1.4 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold YolD PF08863.10 KSA02463.1 - 0.043 13.9 2.0 0.091 12.8 2.0 1.6 1 0 0 1 1 1 0 YolD-like protein NAD_Gly3P_dh_N PF01210.23 KSA02463.1 - 0.054 13.5 0.2 0.07 13.1 0.2 1.2 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Orthopox_B11R PF07033.11 KSA02463.1 - 5.2 6.9 6.8 0.92 9.3 2.3 2.0 2 2 0 2 2 2 0 Orthopoxvirus B11R protein Yos1 PF08571.10 KSA02464.1 - 9.2e-34 115.6 0.7 1.1e-33 115.4 0.7 1.0 1 0 0 1 1 1 1 Yos1-like Dexa_ind PF15198.6 KSA02464.1 - 0.087 12.9 0.2 0.41 10.8 0.1 1.8 2 0 0 2 2 2 0 Dexamethasone-induced TMEM191C PF15194.6 KSA02464.1 - 0.11 12.7 0.1 0.2 11.9 0.1 1.4 1 0 0 1 1 1 0 TMEM191C family RabGAP-TBC PF00566.18 KSA02465.1 - 4.5e-37 127.8 0.4 5.9e-37 127.4 0.4 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PSS PF03034.15 KSA02465.1 - 0.056 13.2 0.0 0.084 12.6 0.0 1.3 1 0 0 1 1 1 0 Phosphatidyl serine synthase RRM_1 PF00076.22 KSA02466.1 - 9.9e-09 34.9 1.1 0.03 14.1 0.0 4.4 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KSA02466.1 - 0.033 14.0 0.1 2.6 8.0 0.0 2.9 3 0 0 3 3 3 0 Occluded RNA-recognition motif Bcr-Abl_Oligo PF09036.10 KSA02466.1 - 0.17 11.9 0.4 0.49 10.4 0.4 1.7 1 0 0 1 1 1 0 Bcr-Abl oncoprotein oligomerisation domain HSP70 PF00012.20 KSA02467.1 - 1.1e-54 185.7 5.5 1.1e-54 185.7 5.5 2.6 2 1 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 KSA02467.1 - 0.013 14.3 0.0 0.025 13.4 0.0 1.4 1 0 0 1 1 1 0 MreB/Mbl protein FGGY_C PF02782.16 KSA02467.1 - 0.19 11.4 0.0 0.39 10.4 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain DnaI_N PF07319.11 KSA02467.1 - 9.1 7.0 8.4 6.7 7.5 0.2 3.4 3 0 0 3 3 3 0 Primosomal protein DnaI N-terminus Pribosyltran PF00156.27 KSA02468.1 - 2.6e-10 40.0 0.0 4e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Fe-ADH PF00465.19 KSA02468.1 - 0.0042 16.0 0.0 0.0063 15.4 0.0 1.3 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Formyl_trans_N PF00551.19 KSA02468.1 - 0.056 13.2 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Formyl transferase UFD1 PF03152.14 KSA02469.1 - 1.4e-68 229.8 0.0 1.7e-68 229.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 DUF3385 PF11865.8 KSA02470.1 - 0.0038 17.1 4.5 0.032 14.1 0.1 2.9 3 0 0 3 3 3 2 Domain of unknown function (DUF3385) RXT2_N PF08595.11 KSA02470.1 - 0.11 12.6 1.0 0.23 11.5 1.0 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal IBN_N PF03810.19 KSA02471.1 - 3.5e-12 46.1 0.6 1.1e-11 44.5 0.1 2.2 2 0 0 2 2 2 1 Importin-beta N-terminal domain Cse1 PF08506.10 KSA02471.1 - 4.9e-11 42.1 10.5 1.5e-10 40.4 6.2 2.9 2 1 0 2 2 2 1 Cse1 YpjP PF14005.6 KSA02471.1 - 0.14 12.2 2.0 2 8.5 0.0 3.0 3 0 0 3 3 3 0 YpjP-like protein RRM_Rrp7 PF17799.1 KSA02472.1 - 2.4e-55 186.7 1.9 2.4e-55 186.7 1.9 1.6 2 0 0 2 2 2 1 Rrp7 RRM-like N-terminal domain RRP7 PF12923.7 KSA02472.1 - 1.5e-28 99.3 12.2 2.8e-28 98.5 12.2 1.5 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain DUF45 PF01863.17 KSA02472.1 - 0.03 14.4 3.1 0.052 13.6 3.1 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF45 Aminotran_4 PF01063.19 KSA02473.1 - 1.1e-23 84.3 0.0 1.4e-23 84.0 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV HAD PF12710.7 KSA02474.1 - 2.8e-16 60.5 0.0 5e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KSA02474.1 - 3.1e-16 60.3 0.2 5.1e-16 59.6 0.2 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KSA02474.1 - 9.8e-12 45.1 4.1 4.6e-10 39.7 0.2 3.3 2 2 1 3 3 3 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KSA02474.1 - 8.8e-06 25.9 0.6 0.00019 21.5 0.6 2.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase CRAL_TRIO PF00650.20 KSA02475.1 - 1.6e-35 122.2 0.0 2.8e-35 121.4 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KSA02475.1 - 1.6e-17 63.5 1.4 2.8e-17 62.6 1.4 1.4 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain DUF1912 PF08930.10 KSA02475.1 - 0.027 14.6 0.2 0.07 13.3 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1912) SR-25 PF10500.9 KSA02475.1 - 0.15 11.7 4.3 0.21 11.2 4.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Tctex-1 PF03645.13 KSA02476.1 - 3.3e-05 24.1 1.5 0.0012 19.1 0.0 2.8 2 1 0 2 2 2 2 Tctex-1 family CENP-Q PF13094.6 KSA02477.1 - 1.1e-24 87.5 3.6 1.1e-24 87.5 3.6 2.2 2 1 1 3 3 3 1 CENP-Q, a CENPA-CAD centromere complex subunit Glyco_hydro_100 PF12899.7 KSA02477.1 - 0.11 11.1 0.7 0.2 10.3 0.7 1.4 1 1 0 1 1 1 0 Alkaline and neutral invertase DUF4477 PF14780.6 KSA02477.1 - 0.21 11.2 4.9 3.5 7.2 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4477) NPV_P10 PF05531.12 KSA02477.1 - 1.3 9.6 7.1 0.3 11.6 1.0 3.0 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein M11L PF11099.8 KSA02477.1 - 2.5 8.4 9.8 0.64 10.3 2.7 2.8 3 0 0 3 3 3 0 Apoptosis regulator M11L like DUF4829 PF16111.5 KSA02478.1 - 0.021 15.6 1.4 0.046 14.5 1.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4829) GP88 PF17338.2 KSA02478.1 - 0.054 12.9 0.3 0.4 10.1 0.0 2.0 2 0 0 2 2 2 0 Gene product 88 Aldedh PF00171.22 KSA02479.1 - 1.9e-179 597.0 0.6 2.2e-179 596.8 0.6 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KSA02479.1 - 0.056 12.9 0.1 1.1 8.7 0.1 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) Amidoligase_2 PF12224.8 KSA02479.1 - 0.065 12.9 0.0 2.9 7.5 0.0 2.1 2 0 0 2 2 2 0 Putative amidoligase enzyme Ribosomal_S24e PF01282.19 KSA02480.1 - 2.8e-35 120.1 0.0 4.4e-35 119.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e RAMPs PF03787.15 KSA02480.1 - 0.031 14.3 0.4 4.2 7.3 0.0 2.1 2 0 0 2 2 2 0 RAMP superfamily DUF572 PF04502.13 KSA02481.1 - 2.6e-60 204.8 40.4 1.5e-59 202.3 40.4 2.1 1 1 0 1 1 1 1 Family of unknown function (DUF572) Mut7-C PF01927.16 KSA02481.1 - 0.005 17.0 0.7 0.005 17.0 0.7 2.9 2 1 2 4 4 4 1 Mut7-C RNAse domain DUF3795 PF12675.7 KSA02481.1 - 0.033 14.6 0.9 0.14 12.6 0.9 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3795) zf-C4_Topoisom PF01396.19 KSA02481.1 - 0.064 13.0 0.7 0.5 10.2 0.0 2.4 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger HypA PF01155.19 KSA02481.1 - 0.11 12.5 0.3 0.29 11.2 0.3 1.7 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn-ribbon_8 PF09723.10 KSA02481.1 - 0.18 11.9 3.6 1 9.5 3.6 2.1 1 1 0 1 1 1 0 Zinc ribbon domain zinc_ribbon_4 PF13717.6 KSA02481.1 - 0.28 11.1 2.1 19 5.3 0.5 2.7 2 0 0 2 2 2 0 zinc-ribbon domain zf_UBZ PF18439.1 KSA02481.1 - 0.29 10.8 3.0 12 5.5 0.3 2.6 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger E6 PF00518.17 KSA02481.1 - 0.88 10.0 5.3 5.1 7.6 1.7 2.8 2 1 0 2 2 2 0 Early Protein (E6) TFIIS_C PF01096.18 KSA02481.1 - 2.6 8.0 4.8 1.4 8.8 0.4 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) Sec6 PF06046.13 KSA02482.1 - 5.1e-198 659.1 5.0 5.1e-198 659.1 5.0 1.6 2 0 0 2 2 2 1 Exocyst complex component Sec6 Cytochrom_B562 PF07361.11 KSA02482.1 - 0.25 12.0 5.1 14 6.4 0.7 3.3 2 1 1 3 3 3 0 Cytochrome b562 RPN7 PF10602.9 KSA02482.1 - 0.3 10.8 5.5 1.3 8.7 5.5 2.2 1 1 0 1 1 1 0 26S proteasome subunit RPN7 BLOC1_2 PF10046.9 KSA02482.1 - 0.42 10.9 14.1 3.2 8.1 0.6 3.8 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.12 KSA02482.1 - 2.5 8.6 13.8 2.4 8.7 3.0 4.4 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein TBCC_N PF16752.5 KSA02482.1 - 2.9 8.3 8.7 1 9.8 3.5 2.9 3 0 0 3 3 3 0 Tubulin-specific chaperone C N-terminal domain DUF4600 PF15372.6 KSA02482.1 - 6.2 7.3 8.8 18 5.8 0.0 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4600) LsmAD PF06741.13 KSA02483.1 - 6.5e-29 100.3 1.8 6.5e-29 100.3 1.8 2.7 3 0 0 3 3 3 1 LsmAD domain SM-ATX PF14438.6 KSA02483.1 - 2.9e-17 62.6 0.1 7.7e-17 61.2 0.1 1.8 1 0 0 1 1 1 1 Ataxin 2 SM domain PAM2 PF07145.15 KSA02483.1 - 0.045 13.4 3.3 0.069 12.9 1.2 2.6 2 0 0 2 2 2 0 Ataxin-2 C-terminal region DUF2347 PF09804.9 KSA02484.1 - 1.8e-74 250.9 1.2 1.8e-74 250.9 1.2 2.4 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.6 KSA02484.1 - 1.9e-15 57.5 11.0 7.1e-15 55.6 7.3 2.9 2 1 0 2 2 2 1 Domain of unknown function (DUF4484) Avl9 PF09794.9 KSA02484.1 - 2.8e-05 23.0 0.0 6.3e-05 21.8 0.0 1.6 1 1 0 1 1 1 1 Transport protein Avl9 SPA PF08616.10 KSA02484.1 - 0.012 15.6 0.1 0.027 14.4 0.1 1.6 1 0 0 1 1 1 0 Stabilization of polarity axis MTH865 PF07747.11 KSA02485.1 - 0.092 12.5 0.0 0.25 11.2 0.0 1.6 2 0 0 2 2 2 0 MTH865-like family DUF202 PF02656.15 KSA02486.1 - 1.2e-15 57.7 3.4 1.2e-15 57.7 3.4 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) UPF0715 PF17094.5 KSA02486.1 - 0.0021 18.6 0.5 0.0031 18.1 0.5 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0715) Gpr1_Fun34_YaaH PF01184.19 KSA02487.1 - 3.4e-88 294.6 23.8 4e-88 294.4 23.8 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF3483 PF11982.8 KSA02487.1 - 4 7.0 6.0 20 4.7 1.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3483) P5-ATPase PF12409.8 KSA02488.1 - 7e-36 123.1 0.1 1.9e-35 121.7 0.1 1.8 1 0 0 1 1 1 1 P5-type ATPase cation transporter E1-E2_ATPase PF00122.20 KSA02488.1 - 2.6e-30 105.3 0.0 6.5e-30 104.0 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KSA02488.1 - 5.9e-13 49.6 0.6 2.8e-06 27.8 0.1 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KSA02488.1 - 1.3e-05 25.1 0.0 2.6e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KSA02488.1 - 0.021 14.5 0.2 0.074 12.8 0.0 2.1 2 0 0 2 2 2 0 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KSA02488.1 - 0.033 13.9 3.3 6.6 6.4 0.0 3.2 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase TAFII55_N PF04658.13 KSA02489.1 - 2.2e-38 131.5 6.4 4.2e-38 130.6 0.1 2.6 2 0 0 2 2 2 1 TAFII55 protein conserved region Pribosyl_synth PF14572.6 KSA02490.1 - 4.5e-44 150.7 2.6 1.5e-37 129.4 1.7 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 KSA02490.1 - 6.7e-39 132.4 0.2 2.9e-38 130.4 0.0 2.1 2 1 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 KSA02490.1 - 1.7e-16 60.2 1.1 3.5e-16 59.1 0.9 1.6 2 0 0 2 2 2 1 Phosphoribosyl transferase domain Sterol_MT_C PF08498.10 KSA02490.1 - 0.011 16.0 0.0 3.5 8.0 0.0 2.4 2 0 0 2 2 2 0 Sterol methyltransferase C-terminal UPRTase PF14681.6 KSA02490.1 - 0.02 14.3 0.1 0.037 13.5 0.1 1.4 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase HAD_2 PF13419.6 KSA02491.1 - 1.7e-17 64.1 0.0 2.4e-17 63.6 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KSA02491.1 - 1.6e-08 35.1 0.0 1.7e-07 31.7 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 KSA02491.1 - 0.023 14.8 0.0 0.059 13.5 0.0 1.6 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase HAD PF12710.7 KSA02491.1 - 0.042 14.3 0.0 0.062 13.7 0.0 1.3 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase BRAP2 PF07576.12 KSA02492.1 - 5.4e-31 106.7 0.0 1.3e-30 105.5 0.0 1.7 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 KSA02492.1 - 6.5e-18 64.8 6.0 1.4e-17 63.7 6.0 1.5 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 KSA02492.1 - 2.4e-08 34.2 10.5 2.4e-08 34.2 10.5 2.1 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KSA02492.1 - 1.9e-06 27.6 10.9 4.6e-06 26.4 10.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KSA02492.1 - 4e-06 26.7 3.3 4e-06 26.7 3.3 2.5 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 KSA02492.1 - 8.2e-06 26.0 6.0 3e-05 24.2 6.0 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger domain TMF_DNA_bd PF12329.8 KSA02492.1 - 3.4e-05 23.7 10.3 0.0002 21.3 6.6 2.3 2 0 0 2 2 2 1 TATA element modulatory factor 1 DNA binding zf-RING_11 PF17123.5 KSA02492.1 - 4.3e-05 23.2 4.5 4.3e-05 23.2 4.5 2.1 2 0 0 2 2 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 KSA02492.1 - 7.4e-05 22.5 9.9 0.00019 21.3 9.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KSA02492.1 - 9e-05 22.3 6.8 9e-05 22.3 6.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KSA02492.1 - 0.00023 21.1 8.0 0.00023 21.1 8.0 2.1 2 0 0 2 2 1 1 zinc-RING finger domain FPP PF05911.11 KSA02492.1 - 0.0028 15.9 6.4 0.004 15.4 6.4 1.1 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil zf-ANAPC11 PF12861.7 KSA02492.1 - 0.005 16.9 4.4 0.015 15.3 4.4 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger MscS_porin PF12795.7 KSA02492.1 - 0.0083 15.7 2.4 0.014 14.9 2.4 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain Rootletin PF15035.6 KSA02492.1 - 0.035 14.1 2.8 0.063 13.3 2.8 1.4 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Cep57_CLD_2 PF14197.6 KSA02492.1 - 0.037 14.1 0.7 0.081 13.0 0.7 1.6 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 GAS PF13851.6 KSA02492.1 - 0.038 13.3 6.9 0.072 12.4 6.9 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding UPF0242 PF06785.11 KSA02492.1 - 0.058 13.5 6.6 0.13 12.4 6.6 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF3450 PF11932.8 KSA02492.1 - 0.066 12.5 3.5 0.056 12.7 1.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) zf-RING_6 PF14835.6 KSA02492.1 - 0.067 13.1 1.5 0.17 11.7 1.5 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 KSA02492.1 - 0.1 12.4 8.1 0.29 11.0 8.1 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain ADIP PF11559.8 KSA02492.1 - 0.21 11.6 6.7 3.6 7.7 3.3 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding zf-C3HC4_4 PF15227.6 KSA02492.1 - 0.21 11.7 6.6 1.1 9.5 6.7 2.3 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING ZapB PF06005.12 KSA02492.1 - 0.23 11.9 5.4 0.088 13.3 1.2 2.1 1 1 2 3 3 3 0 Cell division protein ZapB DivIC PF04977.15 KSA02492.1 - 0.29 10.9 7.2 0.48 10.2 1.7 3.0 1 1 2 3 3 3 0 Septum formation initiator bZIP_1 PF00170.21 KSA02492.1 - 0.38 10.9 6.3 0.44 10.7 1.1 2.8 1 1 0 2 2 2 0 bZIP transcription factor TMF_TATA_bd PF12325.8 KSA02492.1 - 0.41 10.9 4.9 0.67 10.2 2.3 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding FlaC_arch PF05377.11 KSA02492.1 - 0.43 11.0 6.9 0.15 12.4 0.9 2.9 3 0 0 3 3 2 0 Flagella accessory protein C (FlaC) YabA PF06156.13 KSA02492.1 - 0.79 10.4 5.6 1.8 9.2 2.7 2.4 1 1 1 2 2 2 0 Initiation control protein YabA Jnk-SapK_ap_N PF09744.9 KSA02492.1 - 1.2 9.4 5.4 13 6.0 4.9 2.3 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 APG6_N PF17675.1 KSA02492.1 - 1.2 9.7 7.6 11 6.6 7.5 2.3 1 1 0 1 1 1 0 Apg6 coiled-coil region TerY_C PF15616.6 KSA02492.1 - 2.8 8.0 8.0 0.2 11.7 1.5 2.2 2 0 0 2 2 2 0 TerY-C metal binding domain DUF948 PF06103.11 KSA02492.1 - 3.6 7.9 4.6 14 6.0 0.7 3.0 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Prok-RING_4 PF14447.6 KSA02492.1 - 5.8 6.9 23.7 0.28 11.1 12.4 3.1 2 1 1 3 3 2 0 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 KSA02492.1 - 7 6.9 9.8 3.3 7.9 0.2 2.6 2 0 0 2 2 2 0 zinc RING finger of MSL2 NPV_P10 PF05531.12 KSA02492.1 - 8.5 6.9 7.2 39 4.8 0.1 2.6 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein GATA PF00320.27 KSA02493.1 - 8.5e-14 50.9 4.2 1.3e-13 50.2 4.2 1.3 1 0 0 1 1 1 1 GATA zinc finger Nudix_N_2 PF14803.6 KSA02493.1 - 0.059 13.3 1.0 0.11 12.4 1.0 1.4 1 0 0 1 1 1 0 Nudix N-terminal Zn-ribbon_8 PF09723.10 KSA02493.1 - 0.077 13.1 0.2 0.15 12.2 0.2 1.4 1 0 0 1 1 1 0 Zinc ribbon domain zf-ribbon_3 PF13248.6 KSA02493.1 - 0.095 12.1 1.8 0.38 10.2 0.2 2.2 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.7 KSA02493.1 - 0.11 12.5 0.2 0.26 11.3 0.2 1.5 1 1 0 1 1 1 0 Double zinc ribbon Lar_restr_allev PF14354.6 KSA02493.1 - 0.13 12.6 0.5 0.25 11.7 0.5 1.5 1 0 0 1 1 1 0 Restriction alleviation protein Lar DNA_RNApol_7kD PF03604.13 KSA02493.1 - 0.27 10.9 0.1 0.27 10.9 0.1 1.8 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit S1 PF00575.23 KSA02494.1 - 1.8e-58 194.8 40.4 6.6e-15 55.2 0.8 14.4 13 2 0 13 13 13 12 S1 RNA binding domain Suf PF05843.14 KSA02494.1 - 3.1e-05 24.1 14.8 6.8e-05 23.0 0.9 4.0 2 1 0 3 3 3 2 Suppressor of forked protein (Suf) TPR_14 PF13428.6 KSA02494.1 - 0.00043 20.9 0.0 2.1 9.4 0.1 4.3 1 1 3 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 KSA02494.1 - 0.0045 17.5 0.0 12 6.5 0.0 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat S1_2 PF13509.6 KSA02494.1 - 0.031 14.3 1.0 36 4.5 0.0 5.2 5 1 0 5 5 5 0 S1 domain CsrA PF02599.16 KSA02494.1 - 0.078 12.9 3.8 4.2 7.4 0.1 4.4 5 0 0 5 5 5 0 Global regulator protein family YcgR PF07317.12 KSA02494.1 - 0.097 12.6 3.0 14 5.6 0.2 4.2 4 0 0 4 4 4 0 Flagellar regulator YcgR TPR_15 PF13429.6 KSA02494.1 - 0.42 9.8 4.5 4.7 6.3 0.3 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat BUD22 PF09073.10 KSA02494.1 - 3.1 7.0 45.4 2.3 7.5 23.2 2.6 2 1 0 2 2 2 0 BUD22 Opi1 PF08618.10 KSA02496.1 - 1.4e-15 57.5 18.1 7.1e-08 32.1 1.3 3.9 4 1 1 5 5 5 3 Transcription factor Opi1 Cation_efflux PF01545.21 KSA02499.1 - 8.9e-56 188.8 3.2 1.2e-55 188.4 3.2 1.1 1 0 0 1 1 1 1 Cation efflux family Polysacc_synt_3 PF13440.6 KSA02499.1 - 1.2 8.3 6.1 17 4.5 0.0 3.2 3 1 0 3 3 3 0 Polysaccharide biosynthesis protein PNRC PF15365.6 KSA02500.1 - 9.4e-07 28.5 5.2 9.4e-07 28.5 5.2 3.1 3 0 0 3 3 3 1 Proline-rich nuclear receptor coactivator motif Red1 PF07964.11 KSA02500.1 - 8.8 4.4 24.9 12 4.0 24.9 1.0 1 0 0 1 1 1 0 Rec10 / Red1 Zip PF02535.22 KSA02501.1 - 8.1e-24 84.5 18.8 1e-21 77.5 17.4 2.6 1 1 0 1 1 1 1 ZIP Zinc transporter DUF4448 PF14610.6 KSA02502.1 - 1.1e-58 198.1 0.1 1.1e-58 198.1 0.1 1.7 3 0 0 3 3 3 1 Protein of unknown function (DUF4448) Tom37 PF10568.9 KSA02503.1 - 3e-32 111.5 3.9 5.3e-32 110.8 3.9 1.4 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_N_4 PF17172.4 KSA02503.1 - 7.6e-08 33.0 0.5 2.5e-07 31.4 0.5 1.9 1 1 0 1 1 1 1 Glutathione S-transferase N-terminal domain Suf PF05843.14 KSA02504.1 - 2e-70 238.1 36.8 9e-70 236.0 11.3 5.6 3 2 1 4 4 4 1 Suppressor of forked protein (Suf) DASH_Spc19 PF08287.11 KSA02504.1 - 1.3e-05 25.1 6.7 1.3e-05 25.1 6.7 2.4 3 0 0 3 3 3 1 Spc19 DUF4413 PF14372.6 KSA02504.1 - 0.06 13.7 0.2 0.06 13.7 0.2 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4413) ABC1 PF03109.16 KSA02504.1 - 0.24 11.6 3.0 0.93 9.7 0.9 2.6 2 0 0 2 2 2 0 ABC1 family DUF4407 PF14362.6 KSA02504.1 - 1.2 8.4 3.4 3.9 6.7 3.4 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ALMT PF11744.8 KSA02504.1 - 4.5 6.0 9.6 0.22 10.3 3.8 1.7 2 0 0 2 2 2 0 Aluminium activated malate transporter CENP-B_dimeris PF09026.10 KSA02504.1 - 5.1 7.5 9.8 13 6.2 9.8 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DASH_Dad2 PF08654.10 KSA02504.1 - 7.4 7.1 8.9 0.31 11.5 0.4 3.1 4 0 0 4 4 4 0 DASH complex subunit Dad2 RrnaAD PF00398.20 KSA02505.1 - 9e-31 106.9 0.0 1.1e-30 106.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase LMF1 PF06762.14 KSA02505.1 - 0.086 11.9 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 Lipase maturation factor Gon7 PF08738.10 KSA02506.1 - 0.029 14.5 0.0 0.042 13.9 0.0 1.3 1 0 0 1 1 1 0 Gon7 family Vps36_ESCRT-II PF11605.8 KSA02506.1 - 0.13 12.4 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 SNF2_N PF00176.23 KSA02507.1 - 3.2e-70 236.6 1.5 3.2e-70 236.6 1.5 2.5 2 1 0 2 2 2 1 SNF2 family N-terminal domain Bromodomain PF00439.25 KSA02507.1 - 2.2e-19 69.3 0.0 6.2e-19 67.9 0.0 1.8 1 0 0 1 1 1 1 Bromodomain Helicase_C PF00271.31 KSA02507.1 - 3e-19 69.4 0.0 3e-19 69.4 0.0 3.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain SnAC PF14619.6 KSA02507.1 - 4.9e-14 52.7 2.0 4.9e-14 52.7 2.0 3.1 2 0 0 2 2 2 1 Snf2-ATP coupling, chromatin remodelling complex QLQ PF08880.11 KSA02507.1 - 9.8e-11 41.2 3.0 9.8e-11 41.2 3.0 3.7 3 0 0 3 3 3 1 QLQ HSA PF07529.13 KSA02507.1 - 6.2e-06 26.5 14.3 6.2e-06 26.5 14.3 2.9 3 0 0 3 3 3 1 HSA DUF1924 PF09086.11 KSA02507.1 - 1.9 8.9 5.7 4.9 7.6 0.7 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1924) DUF5320 PF17253.2 KSA02507.1 - 2 9.5 7.2 2.3 9.3 0.2 4.0 3 0 0 3 3 3 0 Family of unknown function (DUF5320) PIN_4 PF13638.6 KSA02508.1 - 2.9e-07 30.8 0.0 3.7e-06 27.3 0.0 2.6 1 1 0 1 1 1 1 PIN domain PRR22 PF15776.5 KSA02508.1 - 0.17 11.2 0.1 0.25 10.6 0.1 1.2 1 0 0 1 1 1 0 Proline-rich protein family 22 NOG1_N PF17835.1 KSA02509.1 - 2.9e-50 170.3 1.3 1.4e-49 168.1 0.1 2.6 2 0 0 2 2 2 1 NOG1 N-terminal helical domain NOGCT PF08155.11 KSA02509.1 - 5.2e-27 93.6 2.1 1.5e-26 92.1 2.1 1.9 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.14 KSA02509.1 - 1.9e-25 88.4 0.2 1.9e-25 88.4 0.2 2.2 3 0 0 3 3 3 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 KSA02509.1 - 7.7e-16 58.2 0.0 2.1e-15 56.8 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KSA02509.1 - 5.5e-09 35.7 0.1 1.3e-08 34.6 0.1 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KSA02509.1 - 0.0046 16.9 0.0 2.2 8.1 0.1 2.7 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 KSA02509.1 - 0.014 15.4 1.9 3.5 7.7 0.0 3.2 2 2 0 3 3 3 0 Dynamin family RisS_PPD PF16524.5 KSA02509.1 - 0.039 14.2 0.5 0.13 12.5 0.5 1.9 1 0 0 1 1 1 0 Periplasmic domain of Sensor histidine kinase RisS AAA_16 PF13191.6 KSA02509.1 - 0.055 13.8 0.0 0.34 11.3 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain Roc PF08477.13 KSA02509.1 - 0.11 12.7 0.0 0.4 10.9 0.0 2.0 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Telomere_reg-2 PF10193.9 KSA02509.1 - 0.14 12.6 1.3 4.7 7.7 0.1 2.6 2 0 0 2 2 2 0 Telomere length regulation protein zf-CCCH_4 PF18044.1 KSA02510.1 - 5e-11 42.1 10.3 1.8e-05 24.4 2.7 2.3 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH PF00642.24 KSA02510.1 - 5.5e-10 38.9 12.8 1.1e-05 25.2 3.3 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KSA02510.1 - 4.8e-08 32.8 17.0 8.4e-06 25.7 2.7 2.4 2 0 0 2 2 2 2 Zinc finger domain Torus PF16131.5 KSA02510.1 - 1.4e-06 29.0 10.7 0.0025 18.5 0.5 2.8 2 1 1 3 3 3 2 Torus domain zf-CCCH_3 PF15663.5 KSA02510.1 - 5.1e-05 23.5 0.4 0.00012 22.3 0.4 1.6 1 0 0 1 1 1 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 KSA02510.1 - 0.0039 17.6 12.5 0.1 13.1 2.1 2.6 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger MBA1 PF07961.11 KSA02511.1 - 2e-92 308.5 1.7 2.4e-92 308.2 1.7 1.0 1 0 0 1 1 1 1 MBA1-like protein Radical_SAM_C PF16199.5 KSA02512.1 - 4.1e-32 110.0 0.0 7.7e-32 109.2 0.0 1.5 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 KSA02512.1 - 3e-18 66.7 0.6 7.9e-18 65.4 0.1 1.9 3 0 0 3 3 3 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 KSA02512.1 - 2.9e-10 40.4 0.1 5.5e-10 39.5 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KSA02512.1 - 4.2e-06 26.7 0.0 9.5e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KSA02512.1 - 0.02 15.3 0.0 0.05 14.0 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Pkinase PF00069.25 KSA02513.1 - 2.1e-39 135.5 1.6 5.5e-21 75.1 1.8 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KSA02513.1 - 8.6e-15 54.7 1.6 2.1e-10 40.4 0.6 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase DNA_pol_phi PF04931.13 KSA02513.1 - 0.0064 14.7 4.3 0.011 13.9 4.3 1.3 1 0 0 1 1 1 1 DNA polymerase phi Rtf2 PF04641.12 KSA02513.1 - 0.022 14.1 0.3 0.022 14.1 0.3 1.8 2 0 0 2 2 2 0 Rtf2 RING-finger Vfa1 PF08432.10 KSA02513.1 - 0.29 11.5 6.0 3.2 8.0 0.7 2.6 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 HSP70 PF00012.20 KSA02514.1 - 4.5e-165 550.2 0.1 4.5e-165 550.2 0.1 1.6 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 KSA02514.1 - 5.3e-13 48.5 0.1 7.5e-12 44.7 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein PET10 PF17316.2 KSA02514.1 - 0.0058 16.2 2.2 0.017 14.6 2.2 1.7 1 0 0 1 1 1 1 Petite colonies protein 10 Ketoacyl-synt_C PF02801.22 KSA02514.1 - 0.35 10.9 1.4 5.4 7.1 0.0 2.7 3 0 0 3 3 3 0 Beta-ketoacyl synthase, C-terminal domain NPL4 PF05021.15 KSA02515.1 - 4.7e-140 466.3 0.0 5.8e-140 466.0 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 KSA02515.1 - 1.5e-65 219.8 0.2 2.6e-65 219.0 0.2 1.4 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region Med31 PF05669.12 KSA02515.1 - 0.14 12.1 0.1 0.39 10.7 0.1 1.8 1 0 0 1 1 1 0 SOH1 RabGAP-TBC PF00566.18 KSA02516.1 - 5.4e-35 121.0 3.0 1.3e-34 119.8 3.0 1.7 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Glyco_transf_15 PF01793.16 KSA02517.1 - 1.5e-133 445.1 13.0 1.9e-133 444.7 13.0 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Glyco_transf_15 PF01793.16 KSA02518.1 - 8.8e-135 449.1 8.5 1.1e-134 448.8 8.5 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase PhyH PF05721.13 KSA02519.1 - 2.7e-25 89.9 0.2 3.8e-25 89.4 0.2 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) AA_permease_2 PF13520.6 KSA02520.1 - 1.2e-53 182.5 63.2 1.5e-53 182.2 63.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KSA02520.1 - 6.4e-19 67.9 55.5 9.5e-19 67.3 55.5 1.2 1 0 0 1 1 1 1 Amino acid permease Fungal_trans_2 PF11951.8 KSA02521.1 - 9.3e-22 77.4 3.6 1.3e-21 76.9 3.6 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF4681 PF15732.5 KSA02522.1 - 0.033 14.4 0.0 6.8 7.0 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4681) Peptidase_M41 PF01434.18 KSA02523.1 - 1.4e-64 217.5 0.1 1.4e-64 217.5 0.1 1.5 2 0 0 2 2 1 1 Peptidase family M41 AAA PF00004.29 KSA02523.1 - 7.8e-41 139.6 0.0 1.8e-40 138.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KSA02523.1 - 2.8e-10 39.8 0.1 6.7e-10 38.6 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 KSA02523.1 - 7.5e-06 26.3 0.3 1.8e-05 25.0 0.3 1.6 1 0 0 1 1 1 1 FtsH Extracellular TIP49 PF06068.13 KSA02523.1 - 0.0076 15.5 0.0 0.021 14.1 0.0 1.7 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 KSA02523.1 - 0.012 15.9 0.2 4.5 7.6 0.1 3.1 3 0 0 3 3 3 0 AAA domain CARD PF00619.21 KSA02523.1 - 0.013 15.5 0.1 0.037 14.1 0.1 1.8 1 0 0 1 1 1 0 Caspase recruitment domain RR_TM4-6 PF06459.12 KSA02523.1 - 0.034 14.0 3.2 0.073 12.9 3.2 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RuvB_N PF05496.12 KSA02523.1 - 0.046 13.5 0.0 0.097 12.4 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KSA02523.1 - 0.12 12.4 1.0 0.36 10.8 0.1 2.3 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KSA02523.1 - 0.14 12.6 1.1 0.43 10.9 0.2 2.3 2 1 0 2 2 2 0 AAA ATPase domain IstB_IS21 PF01695.17 KSA02523.1 - 0.17 11.6 0.1 0.63 9.8 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_17 PF13207.6 KSA02523.1 - 0.28 11.6 3.1 0.5 10.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain CDC45 PF02724.14 KSA02523.1 - 0.98 7.6 3.9 1.4 7.1 3.9 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 KSA02523.1 - 4 5.4 9.8 8.9 4.3 9.8 1.5 1 0 0 1 1 1 0 DNA polymerase phi Scm3 PF10384.9 KSA02524.1 - 1.9e-20 72.3 3.8 2e-20 72.2 1.5 2.3 2 0 0 2 2 2 1 Centromere protein Scm3 Terminase_2 PF03592.16 KSA02524.1 - 0.0055 17.2 1.4 0.015 15.8 0.4 2.1 2 0 0 2 2 2 1 Terminase small subunit GCIP PF13324.6 KSA02524.1 - 0.086 12.4 0.1 0.086 12.4 0.1 2.8 3 0 0 3 3 3 0 Grap2 and cyclin-D-interacting OrsD PF12013.8 KSA02524.1 - 7.7 7.0 7.8 14 6.2 0.1 3.2 3 0 0 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D DUF1168 PF06658.12 KSA02525.1 - 0.022 14.5 18.3 0.028 14.2 18.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) ABC_tran_Xtn PF12848.7 KSA02525.1 - 0.023 14.7 14.7 0.028 14.5 14.7 1.1 1 0 0 1 1 1 0 ABC transporter DUF2992 PF11208.8 KSA02525.1 - 4.6 7.5 17.9 5.5 7.2 17.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) CHCH PF06747.13 KSA02526.1 - 2.1e-06 27.7 6.5 4.4e-06 26.7 6.5 1.6 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 KSA02526.1 - 0.0073 16.3 5.4 0.11 12.5 1.2 2.3 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Cmc1 PF08583.10 KSA02526.1 - 0.24 11.5 6.1 0.45 10.6 6.1 1.5 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Metallophos PF00149.28 KSA02527.1 - 5.1e-32 112.0 0.0 8.6e-32 111.3 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.12 KSA02527.1 - 1.6e-25 89.2 0.8 5.6e-25 87.5 0.8 1.9 2 0 0 2 2 2 1 PPP5 TPR repeat region TPR_1 PF00515.28 KSA02527.1 - 5.1e-20 70.4 11.0 4.1e-08 32.7 0.2 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KSA02527.1 - 1.4e-19 68.6 4.5 1e-06 28.4 0.0 4.5 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 KSA02527.1 - 5.6e-13 48.4 4.6 8.7e-10 38.1 0.1 3.2 2 1 2 4 4 4 2 TPR repeat TPR_16 PF13432.6 KSA02527.1 - 4.5e-08 33.6 0.0 9.7e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 KSA02527.1 - 4.9e-08 32.6 14.2 0.0012 18.9 0.0 4.4 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 KSA02527.1 - 1.4e-07 31.4 0.6 1.6e-05 24.9 0.0 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 KSA02527.1 - 6.5e-06 26.6 0.1 6.3e-05 23.4 0.1 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 KSA02527.1 - 3.9e-05 23.9 1.2 0.0017 18.6 0.2 3.1 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KSA02527.1 - 0.00011 22.7 0.0 0.086 13.7 0.0 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KSA02527.1 - 0.00047 20.3 2.3 0.0005 20.2 0.6 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 KSA02527.1 - 0.0039 17.3 0.0 0.0072 16.5 0.0 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 KSA02527.1 - 0.0042 17.0 0.0 0.23 11.6 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 KSA02527.1 - 0.027 15.1 0.2 13 6.7 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.18 KSA02527.1 - 0.039 14.0 5.5 0.56 10.3 0.6 2.9 2 1 0 2 2 2 0 MIT (microtubule interacting and transport) domain Coatomer_WDAD PF04053.14 KSA02528.1 - 6.3e-142 473.7 9.6 1.1e-141 472.9 9.6 1.4 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.11 KSA02528.1 - 2.9e-94 316.1 0.0 4.1e-94 315.6 0.0 1.2 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 KSA02528.1 - 1.4e-43 146.0 21.6 2.8e-09 37.4 0.7 8.5 9 0 0 9 9 9 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KSA02528.1 - 3.9e-11 43.1 3.4 0.00069 19.9 0.0 6.7 3 3 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KSA02528.1 - 0.00063 18.5 8.2 0.12 11.0 0.2 4.0 2 1 2 4 4 4 2 Nucleoporin Nup120/160 eIF2A PF08662.11 KSA02528.1 - 0.026 14.4 0.2 0.69 9.7 0.1 3.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A ENTH PF01417.20 KSA02528.1 - 0.06 13.4 0.5 0.18 11.8 0.5 1.9 1 0 0 1 1 1 0 ENTH domain DUF2457 PF10446.9 KSA02528.1 - 0.26 10.4 3.2 0.48 9.5 3.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Glyco_hydro_16 PF00722.21 KSA02529.1 - 9.7e-47 158.7 6.5 2e-46 157.7 6.5 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Nodulin_late PF07127.11 KSA02529.1 - 0.009 16.3 0.2 0.017 15.4 0.2 1.4 1 0 0 1 1 1 1 Late nodulin protein Chitin_bind_1 PF00187.19 KSA02529.1 - 0.02 15.3 14.4 0.039 14.4 14.4 1.4 1 0 0 1 1 1 0 Chitin recognition protein BRO1 PF03097.18 KSA02530.1 - 1.7e-121 405.7 6.5 1.7e-121 405.7 6.5 2.2 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 KSA02530.1 - 9.4e-23 80.9 14.9 9.4e-23 80.9 14.9 2.1 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV DUF3958 PF13125.6 KSA02530.1 - 0.077 13.2 5.2 3.9 7.7 0.0 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF3958) PhageMin_Tail PF10145.9 KSA02530.1 - 1.7 8.4 5.2 0.41 10.5 0.1 2.6 4 0 0 4 4 4 0 Phage-related minor tail protein SNF2_N PF00176.23 KSA02531.1 - 1.7e-42 145.4 0.0 2e-41 141.9 0.0 2.2 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KSA02531.1 - 8.8e-10 38.9 0.0 4.4e-09 36.7 0.0 2.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PurL_C PF16904.5 KSA02531.1 - 0.037 14.3 0.1 0.13 12.6 0.1 1.9 1 0 0 1 1 1 0 Phosphoribosylformylglycinamidine synthase II C-terminus WD40 PF00400.32 KSA02532.1 - 9.1e-26 89.6 12.5 5e-05 24.0 0.1 6.6 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KSA02532.1 - 1.4e-09 38.1 0.3 0.019 15.3 0.1 5.0 2 2 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Borrelia_rep PF03183.13 KSA02532.1 - 0.15 12.1 1.4 0.6 10.2 1.4 2.0 1 0 0 1 1 1 0 Borrelia repeat protein Cullin PF00888.22 KSA02533.1 - 4.8e-150 501.1 19.9 4.8e-150 501.1 19.9 1.7 1 1 1 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.9 KSA02533.1 - 2.1e-24 85.3 7.3 1e-23 83.1 4.3 2.9 2 0 0 2 2 2 1 Cullin protein neddylation domain HTH_52 PF18576.1 KSA02533.1 - 0.036 14.3 0.1 0.2 11.9 0.1 2.4 1 0 0 1 1 1 0 Helix-turn-helix domain DUF716 PF04819.12 KSA02534.1 - 0.018 14.7 0.1 0.018 14.7 0.1 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF716) MARVEL PF01284.23 KSA02534.1 - 0.075 13.1 7.0 0.19 11.7 7.0 1.7 1 1 0 1 1 1 0 Membrane-associating domain Mit_KHE1 PF10173.9 KSA02535.1 - 1.8e-59 201.0 2.0 2.7e-59 200.5 2.0 1.2 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related SirA PF10747.9 KSA02535.1 - 0.58 10.5 3.9 2.4 8.5 0.2 2.4 2 0 0 2 2 2 0 Sporulation inhibitor of replication protein SirA ATP-synt_ab PF00006.25 KSA02538.1 - 9.1e-109 362.1 0.0 2.5e-108 360.6 0.0 1.8 1 1 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain Hom_end_hint PF05203.16 KSA02538.1 - 1.5e-76 257.3 0.2 2.6e-76 256.6 0.2 1.4 1 0 0 1 1 1 1 Hom_end-associated Hint ATP-synt_ab_Xtn PF16886.5 KSA02538.1 - 5.4e-45 152.2 0.0 1.5e-44 150.7 0.0 1.8 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension Hom_end PF05204.14 KSA02538.1 - 1.2e-30 105.8 0.1 5e-28 97.5 0.0 2.6 2 0 0 2 2 2 2 Homing endonuclease ATP-synt_ab_N PF02874.23 KSA02538.1 - 6.5e-15 55.4 2.0 1.9e-14 53.9 2.0 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Hint_2 PF13403.6 KSA02538.1 - 3.6e-06 27.3 0.0 5.9e-05 23.4 0.0 2.7 3 0 0 3 3 3 1 Hint domain Hint PF01079.20 KSA02538.1 - 0.00012 21.6 0.0 0.00025 20.6 0.0 1.4 1 0 0 1 1 1 1 Hint module LAGLIDADG_3 PF14528.6 KSA02538.1 - 0.0089 16.3 0.0 0.028 14.8 0.0 1.9 1 0 0 1 1 1 1 LAGLIDADG-like domain DUF3919 PF13057.6 KSA02538.1 - 0.076 12.6 1.3 0.25 10.9 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3919) OHCU_decarbox PF09349.10 KSA02539.1 - 9.9e-47 159.3 0.1 1.1e-46 159.1 0.1 1.0 1 0 0 1 1 1 1 OHCU decarboxylase NAD_binding_10 PF13460.6 KSA02540.1 - 1.4e-14 54.4 0.0 2.2e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KSA02540.1 - 2.5e-13 50.1 0.1 1.1e-12 48.0 0.1 2.0 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KSA02540.1 - 3.5e-12 46.4 0.0 5.5e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 KSA02540.1 - 1.6e-10 40.4 0.3 2.6e-10 39.8 0.3 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KSA02540.1 - 3.3e-06 26.4 0.0 5.8e-05 22.3 0.0 2.2 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KSA02540.1 - 0.00016 20.9 0.7 1 8.5 0.1 2.9 1 1 2 3 3 3 2 Male sterility protein Sacchrp_dh_NADP PF03435.18 KSA02540.1 - 0.00096 19.4 0.0 0.0016 18.7 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain GDP_Man_Dehyd PF16363.5 KSA02540.1 - 0.0069 15.8 0.1 0.013 14.9 0.1 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase DDE_Tnp_1_3 PF13612.6 KSA02540.1 - 0.043 13.8 0.0 0.083 12.9 0.0 1.5 1 0 0 1 1 1 0 Transposase DDE domain DUF5031 PF16434.5 KSA02540.1 - 0.1 11.7 0.2 0.15 11.2 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5031) Polysacc_synt_2 PF02719.15 KSA02540.1 - 0.15 11.2 0.1 0.28 10.3 0.1 1.5 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein SRP54_N PF02881.19 KSA02540.1 - 0.15 12.3 0.0 1.3 9.3 0.0 2.5 3 0 0 3 3 3 0 SRP54-type protein, helical bundle domain Metallophos PF00149.28 KSA02541.1 - 2.2e-32 113.2 0.2 3.5e-32 112.6 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Zn_clus PF00172.18 KSA02542.1 - 4.1e-09 36.4 12.4 8.3e-09 35.4 12.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FGGY_C PF02782.16 KSA02543.1 - 4.8e-21 75.4 0.0 8.8e-21 74.5 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KSA02543.1 - 2.8e-08 33.7 0.0 5.3e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain DUF2401 PF10287.9 KSA02544.1 - 1.8e-91 305.8 1.5 1.8e-91 305.8 1.5 2.1 3 0 0 3 3 3 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.9 KSA02544.1 - 1.2e-28 99.3 0.1 3.3e-28 97.9 0.1 1.8 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) Macoilin PF09726.9 KSA02544.1 - 0.066 11.8 11.0 0.08 11.5 11.0 1.1 1 0 0 1 1 1 0 Macoilin family Hid1 PF12722.7 KSA02544.1 - 1.8 6.6 2.9 2.3 6.2 2.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ras PF00071.22 KSA02545.1 - 1.3e-46 158.1 0.0 2e-46 157.5 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KSA02545.1 - 2.8e-22 79.2 0.0 6e-22 78.1 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KSA02545.1 - 5.9e-06 25.9 0.0 9.6e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_7 PF12775.7 KSA02545.1 - 0.0033 17.0 0.2 0.0073 15.8 0.0 1.6 2 0 0 2 2 2 1 P-loop containing dynein motor region PAP2 PF01569.21 KSA02546.1 - 4.8e-21 75.0 1.4 1.4e-20 73.4 1.4 1.8 1 0 0 1 1 1 1 PAP2 superfamily DUF212 PF02681.14 KSA02546.1 - 0.016 15.3 0.4 0.091 12.9 0.0 2.2 2 0 0 2 2 2 0 Divergent PAP2 family PAP2_3 PF14378.6 KSA02546.1 - 0.1 12.2 7.5 0.86 9.3 7.5 2.5 1 1 0 1 1 1 0 PAP2 superfamily Fer4_5 PF12801.7 KSA02546.1 - 4.2 7.4 11.7 18 5.4 11.2 2.4 1 1 0 1 1 1 0 4Fe-4S binding domain GCR1_C PF12550.8 KSA02547.1 - 5.3e-22 77.9 4.0 6.1e-22 77.7 2.3 2.0 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes Syntaxin-6_N PF09177.11 KSA02547.1 - 0.053 14.1 0.6 0.21 12.1 0.6 2.1 1 1 0 1 1 1 0 Syntaxin 6, N-terminal PhaP_Bmeg PF09602.10 KSA02547.1 - 0.15 12.0 3.9 0.31 11.0 1.8 2.4 2 0 0 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) DUF948 PF06103.11 KSA02547.1 - 0.61 10.4 2.8 0.46 10.8 0.3 2.1 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) tRNA_U5-meth_tr PF05958.11 KSA02548.1 - 2.5e-19 69.5 0.6 7.1e-18 64.7 0.6 2.1 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase TRAM PF01938.20 KSA02548.1 - 1.8e-08 34.2 0.0 5.2e-08 32.8 0.0 1.8 1 0 0 1 1 1 1 TRAM domain Methyltransf_31 PF13847.6 KSA02548.1 - 2.3e-06 27.5 0.0 5.3e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KSA02548.1 - 3.4e-05 24.5 0.0 7.3e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KSA02548.1 - 7.7e-05 22.2 0.1 0.00014 21.4 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.10 KSA02548.1 - 0.00033 20.3 0.1 0.00068 19.2 0.1 1.5 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Met_10 PF02475.16 KSA02548.1 - 0.0007 19.4 0.0 0.0014 18.4 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein MTS PF05175.14 KSA02548.1 - 0.0016 18.0 0.0 0.003 17.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 KSA02548.1 - 0.0025 18.4 0.0 0.0057 17.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ribosomal_S21e PF01249.18 KSA02549.1 - 5e-41 138.7 0.1 5.5e-41 138.5 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e Glyco_transf_8 PF01501.20 KSA02550.1 - 1.2e-19 70.9 3.1 3.4e-18 66.1 3.1 2.8 1 1 0 1 1 1 1 Glycosyl transferase family 8 DEAD PF00270.29 KSA02551.1 - 8.5e-47 159.2 0.9 1.4e-46 158.4 0.9 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KSA02551.1 - 3.3e-33 114.3 0.7 5.7e-31 107.1 0.1 3.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KSA02551.1 - 3.8e-08 33.5 0.1 6.7e-08 32.7 0.1 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KSA02551.1 - 7.8e-05 22.5 0.0 0.00013 21.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KSA02551.1 - 0.0001 22.6 0.5 0.00018 21.9 0.1 1.5 2 0 0 2 2 2 1 AAA domain CMS1 PF14617.6 KSA02551.1 - 0.0018 17.7 0.0 0.0044 16.4 0.0 1.6 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.6 KSA02551.1 - 0.0021 18.3 0.1 0.0052 17.1 0.1 1.6 1 1 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.14 KSA02551.1 - 0.033 14.2 0.1 0.19 11.7 0.1 2.1 1 1 0 1 1 1 0 Flavivirus DEAD domain TniB PF05621.11 KSA02551.1 - 0.091 12.2 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein UvrD-helicase PF00580.21 KSA02551.1 - 0.092 12.2 0.8 0.15 11.6 0.8 1.5 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain Fiji_64_capsid PF05880.11 KSA02552.1 - 0.026 13.2 0.0 0.028 13.0 0.0 1.0 1 0 0 1 1 1 0 Fijivirus 64 kDa capsid protein HMG_box PF00505.19 KSA02553.1 - 3.2e-07 30.7 14.7 7.5e-05 23.1 0.3 3.9 3 0 0 3 3 3 3 HMG (high mobility group) box HMG_box_2 PF09011.10 KSA02553.1 - 0.046 14.3 0.1 0.046 14.3 0.1 4.2 4 0 0 4 4 4 0 HMG-box domain KRAB PF01352.27 KSA02553.1 - 4.3 7.1 11.5 1.6 8.5 0.4 3.5 4 0 0 4 4 4 0 KRAB box dUTPase PF00692.19 KSA02554.1 - 5.4e-45 152.2 0.0 6.6e-45 151.9 0.0 1.1 1 0 0 1 1 1 1 dUTPase LETM1 PF07766.13 KSA02555.1 - 2.5e-100 335.2 4.4 2.5e-100 335.2 4.4 1.6 2 0 0 2 2 2 1 LETM1-like protein FRG PF08867.11 KSA02555.1 - 8.9 7.3 6.1 1.1 10.2 0.1 2.6 3 0 0 3 3 3 0 FRG domain PITH PF06201.13 KSA02556.1 - 5.7e-30 104.5 0.8 1e-29 103.7 0.8 1.4 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.20 KSA02556.1 - 4.2e-23 81.3 0.1 1.3e-22 79.7 0.1 1.8 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KSA02556.1 - 1.1e-08 35.4 0.1 5e-08 33.4 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 KSA02556.1 - 9.2e-08 31.9 0.0 2.7e-07 30.4 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.6 KSA02556.1 - 9.2e-08 32.3 0.0 0.00012 22.3 0.0 3.1 1 1 1 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.21 KSA02556.1 - 2.1e-05 24.4 0.1 5.3e-05 23.1 0.1 1.6 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.6 KSA02556.1 - 0.00041 20.5 0.0 0.0012 19.0 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 KSA02556.1 - 0.0016 17.9 0.1 0.0024 17.3 0.1 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family DUF836 PF05768.14 KSA02556.1 - 0.0031 17.9 0.4 0.024 15.0 0.0 2.5 2 1 1 3 3 3 1 Glutaredoxin-like domain (DUF836) Redoxin PF08534.10 KSA02556.1 - 0.032 13.9 0.1 0.1 12.3 0.1 1.8 1 1 0 1 1 1 0 Redoxin HyaE PF07449.11 KSA02556.1 - 0.081 12.9 0.0 0.37 10.8 0.0 2.0 1 1 1 2 2 2 0 Hydrogenase-1 expression protein HyaE TraF PF13728.6 KSA02556.1 - 0.12 12.2 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 F plasmid transfer operon protein Glt_symporter PF03616.14 KSA02557.1 - 0.091 11.4 0.0 0.12 11.0 0.0 1.1 1 0 0 1 1 1 0 Sodium/glutamate symporter Aminotran_1_2 PF00155.21 KSA02558.1 - 4.3e-35 121.6 0.0 4.8e-35 121.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II zf-C3HC4_3 PF13920.6 KSA02560.1 - 1.4e-07 31.2 12.3 2.4e-07 30.5 12.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Sigma_reg_C PF13791.6 KSA02560.1 - 0.015 15.5 0.3 0.14 12.3 0.1 2.4 2 0 0 2 2 2 0 Sigma factor regulator C-terminal zf-CpG_bind_C PF12269.8 KSA02560.1 - 0.022 14.5 0.3 0.041 13.6 0.3 1.3 1 0 0 1 1 1 0 CpG binding protein zinc finger C terminal domain Ycf4 PF02392.16 KSA02560.1 - 0.28 10.7 3.8 8 6.0 2.4 2.6 2 0 0 2 2 2 0 Ycf4 Prok-RING_4 PF14447.6 KSA02560.1 - 2.3 8.1 12.0 4.2 7.3 12.0 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 PROCN PF08083.11 KSA02561.1 - 3.4e-230 763.8 9.2 5.3e-230 763.1 9.2 1.3 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 KSA02561.1 - 3.8e-127 422.6 0.6 9.1e-127 421.4 0.6 1.7 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 KSA02561.1 - 2.6e-83 277.7 2.0 3.1e-83 277.5 0.5 2.0 2 0 0 2 2 2 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 KSA02561.1 - 1.4e-81 271.8 2.0 3.7e-81 270.5 2.0 1.8 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 KSA02561.1 - 1.7e-73 245.0 0.0 4.1e-73 243.8 0.0 1.7 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.9 KSA02561.1 - 8.6e-48 160.6 0.1 2.8e-47 159.0 0.2 1.9 2 0 0 2 2 2 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.11 KSA02561.1 - 8.6e-47 158.1 0.0 1.9e-46 156.9 0.0 1.7 1 0 0 1 1 1 1 PROCT (NUC072) domain JAB PF01398.21 KSA02561.1 - 0.00054 19.9 0.0 0.022 14.7 0.0 3.2 3 0 0 3 3 3 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF5627 PF18620.1 KSA02561.1 - 0.13 12.1 0.4 0.37 10.7 0.4 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5627) NPR3 PF03666.13 KSA02562.1 - 6.7e-135 450.5 6.8 6.7e-135 450.5 6.8 4.9 3 2 1 4 4 4 1 Nitrogen Permease regulator of amino acid transport activity 3 ECH_1 PF00378.20 KSA02563.1 - 1.4e-18 67.1 0.0 1.9e-18 66.7 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KSA02563.1 - 3.4e-09 36.6 0.0 3.8e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase FlbD PF06289.11 KSA02563.1 - 0.00079 19.0 0.0 0.0016 18.0 0.0 1.4 1 0 0 1 1 1 1 Flagellar and Swarming motility proteins Syndecan PF01034.20 KSA02563.1 - 0.14 12.1 0.1 0.26 11.2 0.1 1.4 1 0 0 1 1 1 0 Syndecan domain Arf PF00025.21 KSA02564.1 - 1.1e-79 265.9 0.0 1.3e-79 265.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KSA02564.1 - 1.4e-14 54.3 0.0 1.9e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KSA02564.1 - 1.9e-14 53.5 0.0 2.4e-14 53.2 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 KSA02564.1 - 1.5e-13 50.7 0.0 1.7e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 KSA02564.1 - 8e-12 45.0 1.1 4.4e-08 32.7 0.2 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 KSA02564.1 - 2e-10 40.4 0.0 2.5e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KSA02564.1 - 3.6e-06 27.0 0.0 5.5e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 KSA02564.1 - 0.011 15.1 0.3 0.032 13.5 0.1 1.7 2 0 0 2 2 2 0 6-phosphofructo-2-kinase cobW PF02492.19 KSA02564.1 - 0.12 12.0 0.2 0.87 9.1 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DEP PF00610.21 KSA02567.1 - 7e-15 54.8 0.0 1.7e-14 53.6 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) RhoGAP PF00620.27 KSA02567.1 - 1.2e-13 51.2 0.6 3.6e-13 49.6 0.6 1.9 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.23 KSA02567.1 - 2.2e-11 43.9 0.2 2.2e-11 43.9 0.2 3.5 3 1 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain DUF2423 PF10338.9 KSA02567.1 - 2.3 8.5 9.2 5 7.4 0.6 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2423) Lectin_leg-like PF03388.13 KSA02568.1 - 4.1e-18 65.6 0.5 6.5e-18 64.9 0.5 1.3 1 0 0 1 1 1 1 Legume-like lectin family TBCC_N PF16752.5 KSA02568.1 - 1 9.8 5.5 1.9 8.9 4.8 1.9 1 1 1 2 2 2 0 Tubulin-specific chaperone C N-terminal domain TMPIT PF07851.13 KSA02568.1 - 7.7 5.7 8.6 8.4 5.5 2.0 2.1 1 1 1 2 2 2 0 TMPIT-like protein CLP1_P PF16575.5 KSA02569.1 - 8.8e-55 185.4 0.1 1.4e-54 184.8 0.1 1.3 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop MMR_HSR1 PF01926.23 KSA02569.1 - 0.0018 18.4 0.1 0.012 15.7 0.1 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 KSA02569.1 - 0.0025 17.2 0.0 0.0051 16.2 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_14 PF13173.6 KSA02569.1 - 0.0046 17.0 0.0 0.013 15.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.6 KSA02569.1 - 0.0064 16.3 3.2 0.49 10.2 0.1 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ATPase_2 PF01637.18 KSA02569.1 - 0.033 14.1 0.0 0.073 13.0 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 KSA02569.1 - 0.067 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 KSA02569.1 - 0.13 12.3 0.8 6.5 6.8 0.2 2.5 2 0 0 2 2 2 0 Dynamin family CbiA PF01656.23 KSA02569.1 - 0.13 12.3 0.0 1.3 9.1 0.0 2.3 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.6 KSA02569.1 - 0.14 12.5 0.0 0.32 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 KSA02569.1 - 0.19 11.5 0.7 0.55 10.0 0.0 2.1 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation RNase_H PF00075.24 KSA02570.1 - 4.1e-29 101.6 0.4 1e-28 100.3 0.4 1.6 1 1 0 1 1 1 1 RNase H Cauli_VI PF01693.16 KSA02570.1 - 2.4e-18 66.1 3.6 5e-18 65.1 3.6 1.6 1 0 0 1 1 1 1 Caulimovirus viroplasmin YmgB PF10798.8 KSA02570.1 - 0.047 13.5 0.7 0.15 11.9 0.1 2.0 2 0 0 2 2 2 0 Biofilm development protein YmgB/AriR GATA PF00320.27 KSA02571.1 - 1.5e-16 59.7 2.8 2.7e-16 58.9 2.8 1.5 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.10 KSA02571.1 - 8.9e-11 41.4 2.6 2.1e-10 40.2 2.6 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Rdx PF10262.9 KSA02572.1 - 1.9e-20 72.8 0.0 2.9e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 Rdx family TFIIA PF03153.13 KSA02573.1 - 0.064 13.2 20.3 0.073 13.1 20.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4439 PF14530.6 KSA02573.1 - 0.19 12.4 1.7 0.27 11.9 1.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4439) Zip PF02535.22 KSA02573.1 - 1.2 8.3 9.4 1.3 8.2 9.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter PAT1 PF09770.9 KSA02573.1 - 1.6 6.9 18.1 1.8 6.8 18.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Inhibitor_I9 PF05922.16 KSA02573.1 - 1.7 9.4 9.5 2.2 9.0 8.5 1.7 1 1 0 1 1 1 0 Peptidase inhibitor I9 Presenilin PF01080.17 KSA02573.1 - 3.2 6.4 7.9 3.2 6.4 7.9 1.1 1 0 0 1 1 1 0 Presenilin SOG2 PF10428.9 KSA02573.1 - 7.3 5.7 15.2 9 5.4 15.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DNA_topoisoIV PF00521.20 KSA02574.1 - 2.6e-124 415.4 0.9 2.6e-124 415.4 0.9 2.1 2 1 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 KSA02574.1 - 1.1e-49 168.0 0.0 4.6e-49 165.9 0.0 2.2 1 0 0 1 1 1 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 KSA02574.1 - 1.1e-25 90.1 5.6 2.8e-25 88.8 5.6 1.6 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 KSA02574.1 - 2.8e-15 56.8 0.0 8.4e-15 55.2 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 KSA02574.1 - 7.5e-08 32.5 0.0 5.1e-07 29.9 0.0 2.5 2 0 0 2 2 2 1 Toprim domain HBD PF18534.1 KSA02574.1 - 0.23 11.6 1.9 0.79 9.9 0.0 2.9 3 0 0 3 3 3 0 Helical bundle domain DnaJ PF00226.31 KSA02575.1 - 5.4e-20 71.3 1.0 5.4e-20 71.3 1.0 2.2 2 0 0 2 2 2 1 DnaJ domain IPT PF01745.16 KSA02575.1 - 0.022 14.1 0.7 0.034 13.5 0.7 1.2 1 0 0 1 1 1 0 Isopentenyl transferase Aminotran_5 PF00266.19 KSA02576.1 - 5.9e-27 94.6 0.0 7.2e-27 94.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KSA02576.1 - 0.00015 21.1 0.1 0.00031 20.0 0.1 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II B12-binding PF02310.19 KSA02576.1 - 0.0097 15.9 0.4 0.023 14.7 0.1 1.8 2 0 0 2 2 2 1 B12 binding domain Pox_M2 PF04887.12 KSA02576.1 - 0.11 12.0 0.1 0.17 11.4 0.1 1.2 1 0 0 1 1 1 0 Poxvirus M2 protein ApbA_C PF08546.11 KSA02577.1 - 0.00074 19.7 0.0 0.0016 18.7 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal Alba PF01918.21 KSA02578.1 - 1.1e-07 31.6 0.5 1.9e-07 30.8 0.5 1.5 1 0 0 1 1 1 1 Alba COX6B PF02297.17 KSA02579.1 - 3.7e-19 68.7 4.2 4.4e-19 68.5 4.2 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CX9C PF16860.5 KSA02579.1 - 0.011 15.7 2.6 0.018 15.0 2.6 1.3 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, CHCH PF06747.13 KSA02579.1 - 0.022 14.9 1.4 0.034 14.3 1.4 1.3 1 0 0 1 1 1 0 CHCH domain NFACT-R_1 PF05670.13 KSA02580.1 - 2.3e-34 118.3 0.3 4.3e-34 117.4 0.3 1.5 1 0 0 1 1 1 1 NFACT protein RNA binding domain Mcm10 PF09332.11 KSA02580.1 - 0.11 11.9 9.7 0.1 12.0 7.8 1.7 2 0 0 2 2 2 0 Mcm10 replication factor CemA PF03040.14 KSA02580.1 - 1.3 8.9 7.0 1.8 8.5 6.7 1.4 1 1 0 1 1 1 0 CemA family RabGAP-TBC PF00566.18 KSA02581.1 - 4.1e-40 137.7 9.2 6.9e-40 137.0 9.2 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Phage_head_chap PF11113.8 KSA02581.1 - 0.016 15.3 0.1 0.044 13.9 0.0 1.8 2 0 0 2 2 2 0 Head assembly gene product DUF4867 PF16161.5 KSA02581.1 - 0.039 13.4 0.0 0.078 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4867) Not1 PF04054.15 KSA02582.1 - 5.2e-134 446.8 0.4 1.7e-133 445.1 0.4 1.9 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 KSA02582.1 - 7.8e-83 277.3 6.7 1.9e-82 276.0 5.6 2.3 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain CNOT1_HEAT_N PF16419.5 KSA02582.1 - 3.8e-81 272.1 3.1 3.8e-81 272.1 3.1 3.2 4 0 0 4 4 4 1 CCR4-NOT transcription complex subunit 1 HEAT repeat CNOT1_TTP_bind PF16417.5 KSA02582.1 - 3.9e-48 163.2 1.0 3.9e-48 163.2 1.0 2.3 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 TTP binding domain DUF3819 PF12842.7 KSA02582.1 - 1.1e-33 116.2 1.0 1.1e-33 116.2 1.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3819) CNOT1_HEAT PF16418.5 KSA02582.1 - 2.7e-28 98.9 1.8 1e-27 97.0 1.8 2.1 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 HEAT repeat DUF2420 PF10336.9 KSA02582.1 - 0.078 13.0 1.2 0.44 10.6 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2420) UQ_con PF00179.26 KSA02583.1 - 6.7e-45 152.2 0.0 8.2e-45 151.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.10 KSA02583.1 - 2e-19 69.1 0.2 3.3e-19 68.4 0.2 1.4 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Prok-E2_B PF14461.6 KSA02583.1 - 0.0056 16.4 0.0 0.0085 15.8 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KSA02583.1 - 0.021 15.1 0.0 0.034 14.4 0.0 1.6 1 0 0 1 1 1 0 RWD domain DUF1421 PF07223.11 KSA02583.1 - 0.024 14.4 0.2 0.14 12.0 0.1 2.0 2 0 0 2 2 2 0 UBA-like domain (DUF1421) UBA PF00627.31 KSA02583.1 - 0.025 14.5 0.2 0.083 12.8 0.0 1.9 2 0 0 2 2 2 0 UBA/TS-N domain FeoA PF04023.14 KSA02583.1 - 0.2 12.0 0.0 0.37 11.1 0.0 1.4 1 0 0 1 1 1 0 FeoA domain NTF2 PF02136.20 KSA02584.1 - 2.5e-13 50.6 0.9 5.7e-13 49.5 0.1 2.0 2 0 0 2 2 2 1 Nuclear transport factor 2 (NTF2) domain Branch PF02485.21 KSA02584.1 - 0.0057 16.2 0.3 0.013 15.0 0.3 1.6 1 0 0 1 1 1 1 Core-2/I-Branching enzyme GREB1 PF15782.5 KSA02584.1 - 8.2 3.4 29.1 13 2.7 29.1 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer CDC50 PF03381.15 KSA02585.1 - 9.8e-92 307.4 1.0 1.4e-91 306.9 1.0 1.2 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family CAF1 PF04857.20 KSA02586.1 - 2e-06 27.2 11.8 0.00077 18.7 0.1 3.0 2 1 1 3 3 3 2 CAF1 family ribonuclease NGP1NT PF08153.12 KSA02587.1 - 9.5e-51 171.3 0.5 2e-50 170.3 0.5 1.6 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 KSA02587.1 - 3e-17 62.8 0.0 5.3e-13 49.0 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 KSA02587.1 - 0.00011 21.8 0.0 0.00058 19.4 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B Arf PF00025.21 KSA02587.1 - 0.0006 19.3 0.1 0.15 11.5 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KSA02587.1 - 0.00085 19.3 0.0 0.0019 18.1 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase GTP_EFTU PF00009.27 KSA02587.1 - 0.0054 16.3 0.0 0.37 10.3 0.0 3.0 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KSA02587.1 - 0.02 15.0 2.5 0.83 9.7 0.0 3.7 3 1 1 4 4 4 0 Dynamin family DUF3818 PF12825.7 KSA02588.1 - 2.6e-104 348.9 14.3 5.5e-104 347.8 14.3 1.6 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 KSA02588.1 - 3.9e-34 117.4 5.2 3.9e-34 117.4 5.2 2.3 2 0 0 2 2 2 1 PX-associated PX PF00787.24 KSA02588.1 - 1.9e-07 31.0 1.9 1.9e-07 31.0 1.9 3.7 3 1 0 3 3 3 1 PX domain DUF1350 PF07082.11 KSA02588.1 - 0.019 14.2 0.1 0.04 13.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1350) Transgly PF00912.22 KSA02588.1 - 0.095 12.1 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Transglycosylase LicD PF04991.13 KSA02589.1 - 6.6e-21 75.5 1.3 6.6e-21 75.5 1.3 4.4 4 1 1 5 5 5 2 LicD family HlyIII PF03006.20 KSA02590.1 - 6.1e-55 186.4 4.7 8.3e-55 185.9 4.7 1.1 1 0 0 1 1 1 1 Haemolysin-III related Fib_alpha PF08702.10 KSA02590.1 - 1.7 8.9 6.9 2.4 8.3 0.7 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Sugar_tr PF00083.24 KSA02591.1 - 3.1e-119 398.8 19.8 3.5e-119 398.6 19.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KSA02591.1 - 4.5e-18 65.3 37.1 1e-14 54.3 12.3 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KSA02591.1 - 0.0073 14.8 2.1 0.025 13.0 1.0 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KSA02593.1 - 1.1e-100 337.7 31.2 1.3e-100 337.4 31.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KSA02593.1 - 2.6e-20 72.7 28.5 2.6e-20 72.7 28.5 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily AA_permease PF00324.21 KSA02594.1 - 2.4e-103 346.3 48.5 3.1e-103 346.0 48.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KSA02594.1 - 2e-35 122.5 48.4 2.5e-35 122.2 48.4 1.0 1 0 0 1 1 1 1 Amino acid permease Sod_Fe_C PF02777.18 KSA02595.1 - 6.7e-31 106.5 1.0 1.3e-30 105.6 1.0 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KSA02595.1 - 1.1e-29 102.7 2.8 2e-29 101.9 2.8 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain HHH_2 PF12826.7 KSA02595.1 - 0.084 13.0 0.0 0.36 10.9 0.0 1.9 2 0 0 2 2 2 0 Helix-hairpin-helix motif Annexin PF00191.20 KSA02595.1 - 0.092 12.8 0.2 0.17 12.0 0.2 1.5 1 0 0 1 1 1 0 Annexin MFS_1 PF07690.16 KSA02596.1 - 3.9e-23 82.0 15.6 3.9e-23 82.0 15.6 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 KSA02596.1 - 0.0075 15.6 3.9 0.0083 15.5 0.8 2.3 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF4293 PF14126.6 KSA02596.1 - 0.032 14.5 0.1 0.13 12.5 0.1 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4293) DUF3951 PF13131.6 KSA02596.1 - 0.98 9.7 0.0 0.98 9.7 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3951) TauD PF02668.16 KSA02597.1 - 2.9e-55 187.9 0.3 4.1e-55 187.5 0.3 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family AA_permease PF00324.21 KSA02598.1 - 0.019 13.6 1.3 0.023 13.3 1.3 1.1 1 0 0 1 1 1 0 Amino acid permease DUF3578 PF12102.8 KSA02598.1 - 0.038 13.6 0.4 0.044 13.3 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3578) AA_permease PF00324.21 KSA02599.1 - 3.2e-30 105.2 12.5 3.7e-30 104.9 12.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KSA02599.1 - 9.6e-10 37.8 12.9 1.1e-09 37.7 12.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KSA02600.1 - 1.3e-12 47.1 10.0 1.4e-12 46.9 10.0 1.0 1 0 0 1 1 1 1 Amino acid permease DUF3784 PF12650.7 KSA02600.1 - 0.031 14.5 1.6 0.045 13.9 1.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3784) PALP PF00291.25 KSA02601.1 - 6.5e-59 199.7 0.0 7.9e-59 199.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 KSA02601.1 - 4.1e-46 154.7 0.5 1.2e-24 85.9 0.1 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase GTP_EFTU PF00009.27 KSA02602.1 - 3.9e-49 166.8 0.0 6.8e-49 166.1 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 KSA02602.1 - 1.7e-39 134.2 7.3 6.5e-39 132.4 6.8 2.1 2 0 0 2 2 2 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 KSA02602.1 - 7.8e-22 77.1 0.0 1.7e-21 76.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KSA02602.1 - 1.9e-07 31.4 0.0 4.3e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KSA02602.1 - 0.00014 21.9 0.1 0.00035 20.6 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase Ras PF00071.22 KSA02602.1 - 0.001 18.7 0.0 0.002 17.8 0.0 1.5 1 0 0 1 1 1 1 Ras family EFG_II PF14492.6 KSA02602.1 - 0.0045 17.1 0.0 0.015 15.4 0.0 2.0 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1_Xtn PF16897.5 KSA02602.1 - 0.0049 16.9 0.1 0.02 14.9 0.0 2.1 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain RF3_C PF16658.5 KSA02602.1 - 0.0084 15.9 0.1 0.023 14.5 0.0 1.7 2 0 0 2 2 2 1 Class II release factor RF3, C-terminal domain SRPRB PF09439.10 KSA02602.1 - 0.019 14.4 0.0 0.045 13.2 0.0 1.7 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Aminotran_5 PF00266.19 KSA02603.1 - 2.1e-37 129.0 0.0 2.5e-37 128.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Mog1 PF04603.12 KSA02603.1 - 0.017 15.5 0.0 0.047 14.1 0.0 1.7 2 0 0 2 2 2 0 Ran-interacting Mog1 protein TBSV_P22 PF03558.13 KSA02603.1 - 0.095 12.2 0.1 0.17 11.4 0.1 1.3 1 0 0 1 1 1 0 TBSV core protein P21/P22 Hus1 PF04005.12 KSA02604.1 - 1.9e-81 273.4 2.1 2.1e-81 273.2 2.1 1.0 1 0 0 1 1 1 1 Hus1-like protein LSM PF01423.22 KSA02605.1 - 8e-17 60.7 0.3 1.1e-16 60.2 0.3 1.2 1 0 0 1 1 1 1 LSM domain CPSF73-100_C PF11718.8 KSA02606.1 - 5.5e-67 225.5 1.2 9.2e-67 224.8 1.2 1.4 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 KSA02606.1 - 2.1e-31 108.5 0.0 5.1e-31 107.2 0.0 1.7 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.27 KSA02606.1 - 2.3e-20 73.4 0.6 4.3e-20 72.6 0.6 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 KSA02606.1 - 5.1e-18 65.2 0.0 1.3e-17 63.9 0.0 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 KSA02606.1 - 5.9e-16 58.2 0.0 1.3e-15 57.1 0.0 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 KSA02606.1 - 1.3e-05 24.8 0.2 9.9e-05 21.9 0.2 2.2 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KSA02606.1 - 2.5e-05 24.2 0.0 8.9e-05 22.4 0.0 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 KSA02606.1 - 0.00092 18.5 0.0 0.002 17.4 0.0 1.5 1 0 0 1 1 1 1 Putative beta-lactamase-like family CPSF100_C PF13299.6 KSA02606.1 - 0.089 13.0 1.6 0.22 11.7 1.6 1.5 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal MCM PF00493.23 KSA02607.1 - 1.1e-103 345.1 0.1 2.2e-103 344.2 0.1 1.5 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KSA02607.1 - 1.5e-38 131.5 0.3 2.8e-38 130.6 0.3 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KSA02607.1 - 6.3e-27 93.8 1.9 1.8e-26 92.4 1.9 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KSA02607.1 - 9.9e-15 55.0 1.6 1.6e-14 54.3 0.4 1.9 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 KSA02607.1 - 1.8e-06 27.5 0.0 0.00069 19.1 0.0 2.5 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KSA02607.1 - 1.1e-05 25.4 0.0 4.9e-05 23.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KSA02607.1 - 0.00015 21.7 0.1 0.0023 17.8 0.0 2.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KSA02607.1 - 0.04 13.6 0.0 1.3 8.7 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA PF00004.29 KSA02607.1 - 0.1 13.0 0.0 0.39 11.1 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_lid_7 PF17867.1 KSA02607.1 - 0.11 12.7 0.7 0.28 11.4 0.1 2.0 2 0 0 2 2 2 0 Midasin AAA lid domain RF-1 PF00472.20 KSA02608.1 - 2.7e-23 82.1 4.1 4e-23 81.6 4.1 1.3 1 0 0 1 1 1 1 RF-1 domain OGG_N PF07934.12 KSA02608.1 - 0.43 10.7 3.0 1.1 9.4 3.0 1.6 1 1 0 1 1 1 0 8-oxoguanine DNA glycosylase, N-terminal domain Peptidase_S49_N PF08496.10 KSA02608.1 - 0.5 10.4 5.1 0.63 10.1 5.1 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal ADIP PF11559.8 KSA02610.1 - 4e-40 137.4 19.1 4e-40 137.4 19.1 2.5 3 0 0 3 3 3 1 Afadin- and alpha -actinin-Binding Tropomyosin_1 PF12718.7 KSA02610.1 - 0.00098 19.3 3.2 0.00098 19.3 3.2 3.8 3 1 1 4 4 4 1 Tropomyosin like Glutaredoxin2_C PF04399.13 KSA02610.1 - 0.013 15.3 2.0 0.013 15.3 2.0 2.2 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain betaPIX_CC PF16523.5 KSA02610.1 - 0.033 14.0 3.8 0.12 12.3 3.8 1.9 1 0 0 1 1 1 0 betaPIX coiled coil NYD-SP28 PF14772.6 KSA02610.1 - 0.059 13.4 0.7 0.059 13.4 0.7 3.8 4 0 0 4 4 4 0 Sperm tail HR1 PF02185.16 KSA02610.1 - 0.076 13.1 11.8 1.4 9.1 2.1 3.7 3 0 0 3 3 3 0 Hr1 repeat CLZ PF16526.5 KSA02610.1 - 0.89 10.0 7.7 0.41 11.0 1.7 3.2 3 1 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DWNN PF08783.11 KSA02610.1 - 1.4 9.2 8.3 0.19 12.0 1.4 2.9 2 1 0 2 2 2 0 DWNN domain PKcGMP_CC PF16808.5 KSA02610.1 - 5 7.1 13.7 0.18 11.6 0.5 3.3 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase SlyX PF04102.12 KSA02610.1 - 5.8 7.6 6.9 2.3 8.9 0.2 3.5 3 1 0 4 4 4 0 SlyX DHR10 PF18595.1 KSA02610.1 - 6.4 6.9 14.2 0.29 11.2 5.2 3.0 2 1 0 3 3 3 0 Designed helical repeat protein 10 domain ATP_sub_h PF10775.9 KSA02611.1 - 3.3e-22 78.2 0.7 5.1e-22 77.6 0.7 1.2 1 0 0 1 1 1 1 ATP synthase complex subunit h zf-U1 PF06220.12 KSA02612.1 - 1.1e-15 57.1 15.8 1.1e-15 57.1 15.8 2.3 2 1 0 2 2 2 1 U1 zinc finger LUC7 PF03194.15 KSA02612.1 - 0.076 12.7 0.5 0.076 12.7 0.5 1.4 2 0 0 2 2 2 0 LUC7 N_terminus Ras PF00071.22 KSA02613.1 - 5.1e-49 166.0 0.0 6.2e-49 165.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KSA02613.1 - 2.8e-29 101.8 0.0 7.4e-29 100.4 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KSA02613.1 - 1.8e-10 40.5 0.0 2.3e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.22 KSA02613.1 - 0.00048 20.5 0.1 0.0022 18.4 0.1 2.0 1 1 0 1 1 1 1 RNA helicase MMR_HSR1 PF01926.23 KSA02613.1 - 0.00086 19.4 0.0 0.0016 18.5 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KSA02613.1 - 0.00095 18.6 0.0 0.0012 18.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KSA02613.1 - 0.02 14.8 0.1 5.8 6.8 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase Pox_A32 PF04665.12 KSA02613.1 - 0.021 14.3 0.1 0.039 13.4 0.1 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein G-alpha PF00503.20 KSA02613.1 - 0.03 13.5 2.2 1.6 7.8 0.1 2.6 2 1 1 3 3 3 0 G-protein alpha subunit AAA_7 PF12775.7 KSA02613.1 - 0.038 13.5 0.1 0.066 12.7 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 KSA02613.1 - 0.047 13.4 0.2 0.061 13.0 0.2 1.4 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 KSA02613.1 - 0.086 12.8 0.1 0.19 11.7 0.1 1.6 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 KSA02613.1 - 0.098 12.8 0.2 0.22 11.7 0.2 1.5 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 KSA02613.1 - 0.1 11.9 0.2 0.16 11.3 0.2 1.2 1 0 0 1 1 1 0 KaiC AAA_16 PF13191.6 KSA02613.1 - 0.14 12.5 0.1 0.22 11.9 0.1 1.4 1 0 0 1 1 1 0 AAA ATPase domain Septin PF00735.18 KSA02613.1 - 0.16 11.2 0.4 0.25 10.6 0.0 1.5 2 0 0 2 2 2 0 Septin RRM_1 PF00076.22 KSA02614.1 - 2.1e-14 53.1 5.2 0.00054 19.7 0.0 4.4 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM PF10378.9 KSA02614.1 - 5.4e-14 51.6 8.7 5.4e-14 51.6 8.7 3.4 2 1 1 3 3 3 1 Putative RRM domain Aa_trans PF01490.18 KSA02615.1 - 1.4e-56 191.9 35.1 1.9e-56 191.6 35.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KSA02615.1 - 0.0006 19.0 16.5 0.0006 19.0 16.5 2.2 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family Doppel PF11466.8 KSA02615.1 - 1.6 8.4 5.2 13 5.5 1.5 3.1 2 0 0 2 2 2 0 Prion-like protein Doppel KilA-N PF04383.13 KSA02616.1 - 9e-07 28.7 0.0 4.5e-05 23.3 0.0 2.5 1 1 0 1 1 1 1 KilA-N domain Glyoxalase PF00903.25 KSA02617.1 - 6.3e-15 55.5 0.0 2.3e-13 50.4 0.0 2.3 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KSA02617.1 - 5.3e-09 36.3 0.0 3.7e-06 27.2 0.0 2.6 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_5 PF14696.6 KSA02617.1 - 5e-07 30.0 0.0 0.002 18.3 0.0 2.6 3 0 0 3 3 3 2 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_3 PF13468.6 KSA02617.1 - 0.0034 17.5 0.0 0.051 13.7 0.0 2.5 2 1 0 2 2 2 1 Glyoxalase-like domain RTA1 PF04479.13 KSA02618.1 - 2.3e-74 249.5 13.7 2.3e-74 249.5 13.7 2.1 1 1 1 2 2 2 1 RTA1 like protein Ribosomal_L28e PF01778.17 KSA02619.1 - 3.8e-39 134.0 3.9 3.8e-39 134.0 3.9 2.0 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.14 KSA02619.1 - 2e-31 108.5 17.9 2e-31 108.5 17.9 2.8 1 1 1 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.10 KSA02619.1 - 0.00021 20.8 23.8 0.00027 20.4 23.8 1.1 1 0 0 1 1 1 1 BUD22 PYC_OADA PF02436.18 KSA02619.1 - 0.16 11.7 3.7 0.3 10.8 3.7 1.6 1 1 0 1 1 1 0 Conserved carboxylase domain Nop14 PF04147.12 KSA02619.1 - 4.3 5.4 32.4 5.9 5.0 32.4 1.2 1 0 0 1 1 1 0 Nop14-like family CH PF00307.31 KSA02620.1 - 2e-14 53.7 0.3 3.3e-14 53.0 0.0 1.5 2 0 0 2 2 2 1 Calponin homology (CH) domain IMPDH PF00478.25 KSA02621.1 - 1.3e-133 445.3 0.5 1.5e-133 445.1 0.5 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 KSA02621.1 - 1e-12 48.3 0.5 1.7e-05 25.2 0.0 2.7 3 0 0 3 3 3 2 CBS domain NMO PF03060.15 KSA02621.1 - 1.9e-09 37.4 0.4 4.3e-05 23.1 0.6 2.4 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.18 KSA02621.1 - 3.1e-08 33.0 1.3 7.7e-08 31.7 1.3 1.6 1 0 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 KSA02621.1 - 5e-05 22.9 0.9 0.00062 19.3 0.9 2.2 1 1 0 1 1 1 1 Histidine biosynthesis protein ThiG PF05690.14 KSA02621.1 - 0.00041 19.7 0.3 0.00089 18.6 0.3 1.5 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG Aldolase PF01081.19 KSA02621.1 - 0.0048 16.3 0.0 0.014 14.8 0.0 1.7 1 0 0 1 1 1 1 KDPG and KHG aldolase NanE PF04131.14 KSA02621.1 - 0.0054 15.9 0.0 0.011 14.9 0.0 1.5 1 0 0 1 1 1 1 Putative N-acetylmannosamine-6-phosphate epimerase B56 PF01603.20 KSA02622.1 - 3.7e-172 573.0 12.3 4.9e-162 539.7 10.5 2.1 2 0 0 2 2 2 2 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.7 KSA02622.1 - 0.047 13.6 4.9 2.2 8.2 0.4 2.8 3 0 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal PI3K_1B_p101 PF10486.9 KSA02622.1 - 9 3.9 7.8 13 3.4 7.8 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Mpv17_PMP22 PF04117.12 KSA02623.1 - 3.6e-21 75.2 4.3 6.8e-21 74.3 4.3 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family Mpv17_PMP22 PF04117.12 KSA02624.1 - 1e-19 70.5 3.3 2.3e-19 69.3 3.3 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family Pil1 PF13805.6 KSA02625.1 - 1.4e-126 421.4 0.5 1.6e-126 421.2 0.5 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 FAM92 PF06730.11 KSA02625.1 - 0.026 14.0 0.9 0.041 13.3 0.9 1.3 1 0 0 1 1 1 0 FAM92 protein DUF498 PF04430.14 KSA02627.1 - 5.1e-16 58.7 0.0 7.2e-16 58.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) STD1 PF17235.2 KSA02628.1 - 5.9e-44 150.2 6.3 5.9e-44 150.2 6.3 2.0 2 0 0 2 2 2 1 STD1/MTH1 Cofilin_ADF PF00241.20 KSA02629.1 - 7.8e-33 112.9 0.7 8.4e-16 57.9 0.1 2.2 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein CTNNB1_binding PF08347.11 KSA02629.1 - 0.3 11.3 3.4 1 9.5 0.2 2.2 1 1 1 2 2 2 0 N-terminal CTNNB1 binding PHF5 PF03660.14 KSA02631.1 - 2.4e-49 165.9 12.0 2.7e-49 165.7 12.0 1.0 1 0 0 1 1 1 1 PHF5-like protein zinc-ribbons_6 PF07191.12 KSA02631.1 - 0.00035 20.5 5.4 0.00035 20.5 5.4 1.9 1 1 0 1 1 1 1 zinc-ribbons DZR PF12773.7 KSA02631.1 - 8.4 6.5 13.3 9.7 6.3 0.5 2.7 1 1 1 2 2 2 0 Double zinc ribbon BCAS2 PF05700.11 KSA02632.1 - 1.1e-10 41.6 4.8 1.5e-10 41.1 4.8 1.2 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) YqzL PF14006.6 KSA02632.1 - 1.6 9.2 7.5 0.44 10.9 0.4 2.5 2 1 0 2 2 2 0 YqzL-like protein Ribosomal_L5_C PF00673.21 KSA02633.1 - 1.9e-21 76.0 0.0 2.9e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 KSA02633.1 - 8.6e-19 67.6 0.0 2.2e-18 66.3 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L5 HTH_ABP1_N PF18107.1 KSA02633.1 - 0.013 15.2 0.1 0.027 14.2 0.1 1.5 1 0 0 1 1 1 0 Fission yeast centromere protein N-terminal domain Proteasome PF00227.26 KSA02634.1 - 1.2e-47 161.8 0.1 1.5e-47 161.6 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Forkhead PF00250.18 KSA02635.1 - 2e-19 69.6 0.2 2.5e-18 66.1 0.0 2.7 3 0 0 3 3 3 1 Forkhead domain FHA PF00498.26 KSA02635.1 - 1e-09 38.6 0.1 2.5e-09 37.3 0.1 1.7 1 0 0 1 1 1 1 FHA domain FHA_2 PF17913.1 KSA02635.1 - 0.12 12.6 0.0 2 8.7 0.0 2.5 2 0 0 2 2 2 0 FHA domain Selenoprotein_S PF06936.11 KSA02635.1 - 2.1 8.1 9.8 0.55 10.0 1.7 3.0 2 0 0 2 2 2 0 Selenoprotein S (SelS) Cellulase PF00150.18 KSA02636.1 - 2.2e-09 37.2 7.6 3.5e-08 33.2 7.6 2.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) SLX9 PF15341.6 KSA02637.1 - 1.3e-10 41.8 2.1 1.5e-10 41.6 2.1 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 RasGEF PF00617.19 KSA02638.1 - 6.7e-45 153.5 4.2 8.3e-45 153.1 2.5 2.2 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 KSA02638.1 - 4.2e-13 49.4 3.1 4.5e-12 46.1 3.1 3.0 1 0 0 1 1 1 1 RasGEF N-terminal motif Peroxin-22 PF12827.7 KSA02639.1 - 9.4e-33 112.5 0.3 1.3e-32 112.1 0.3 1.2 1 0 0 1 1 1 1 Peroxisomal biogenesis protein family SOR_SNZ PF01680.17 KSA02640.1 - 4.4e-105 350.0 3.2 5.9e-105 349.6 3.2 1.2 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 KSA02640.1 - 4.2e-10 39.4 2.0 1.6e-08 34.1 0.0 2.4 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG Dus PF01207.17 KSA02640.1 - 2.7e-06 26.7 0.0 0.0013 17.9 0.0 2.3 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) IGPS PF00218.21 KSA02640.1 - 0.0023 17.1 0.0 0.057 12.6 0.0 2.3 2 1 0 2 2 2 1 Indole-3-glycerol phosphate synthase NanE PF04131.14 KSA02640.1 - 0.0029 16.8 0.9 0.07 12.3 0.0 2.8 2 2 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase His_biosynth PF00977.21 KSA02640.1 - 0.0094 15.4 0.2 0.85 9.0 0.0 2.9 2 1 1 3 3 3 2 Histidine biosynthesis protein NMO PF03060.15 KSA02640.1 - 0.054 12.9 1.4 2.6 7.4 0.0 2.2 2 0 0 2 2 2 0 Nitronate monooxygenase FMN_dh PF01070.18 KSA02640.1 - 0.072 12.1 0.5 0.19 10.7 0.0 1.9 2 0 0 2 2 2 0 FMN-dependent dehydrogenase TetR_C_27 PF17935.1 KSA02640.1 - 0.13 12.4 0.0 0.42 10.7 0.0 1.8 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain DUF3606 PF12244.8 KSA02640.1 - 0.15 12.0 0.0 0.45 10.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) SNO PF01174.19 KSA02641.1 - 2.8e-62 209.9 0.0 5.4e-60 202.5 0.0 2.0 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 KSA02641.1 - 1.4e-08 34.6 0.0 1.9e-08 34.2 0.0 1.4 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain DJ-1_PfpI PF01965.24 KSA02641.1 - 0.0097 15.7 0.0 0.029 14.2 0.0 1.7 2 0 0 2 2 2 1 DJ-1/PfpI family Peptidase_S51 PF03575.17 KSA02641.1 - 0.024 14.3 0.0 0.036 13.7 0.0 1.2 1 0 0 1 1 1 0 Peptidase family S51 Peptidase_C26 PF07722.13 KSA02641.1 - 0.18 11.5 0.0 3.3 7.4 0.0 2.4 2 1 0 2 2 2 0 Peptidase C26 IML1 PF12257.8 KSA02642.1 - 4e-103 344.5 0.7 7.3e-103 343.6 0.7 1.5 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 KSA02642.1 - 5.5e-24 84.0 0.3 1.4e-23 82.7 0.3 1.8 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Homoserine_dh PF00742.19 KSA02643.1 - 4e-52 176.6 0.0 5.5e-52 176.2 0.0 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 KSA02643.1 - 5.8e-19 68.9 0.0 9.6e-19 68.2 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Pyr_redox PF00070.27 KSA02643.1 - 0.015 15.9 0.2 3.6 8.2 0.0 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase YukD PF08817.10 KSA02643.1 - 0.074 13.7 0.0 0.33 11.7 0.0 2.0 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukD Cellulase PF00150.18 KSA02644.1 - 6.6e-13 48.7 1.6 6.6e-13 48.7 1.6 1.5 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.15 KSA02644.1 - 0.0071 15.7 2.9 0.061 12.7 0.3 2.3 2 0 0 2 2 2 2 Beta-galactosidase MAS20 PF02064.15 KSA02645.1 - 5.3e-44 149.4 1.3 6.5e-44 149.2 1.3 1.1 1 0 0 1 1 1 1 MAS20 protein import receptor DUF1451 PF07295.11 KSA02645.1 - 0.037 14.1 0.7 0.054 13.5 0.7 1.2 1 0 0 1 1 1 0 Zinc-ribbon containing domain Mgm101p PF06420.12 KSA02647.1 - 1.4e-85 285.0 0.0 2e-85 284.5 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 LicD PF04991.13 KSA02648.1 - 2.3e-20 73.7 5.4 2.1e-18 67.3 1.8 4.8 4 1 1 5 5 5 2 LicD family DUF3567 PF12091.8 KSA02648.1 - 0.11 12.7 0.8 0.25 11.5 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3567) DUF3740 PF12548.8 KSA02648.1 - 1.3 9.4 4.3 0.77 10.2 0.1 2.7 3 0 0 3 3 3 0 Sulfatase protein LicD PF04991.13 KSA02649.1 - 6.4e-24 85.3 3.7 9.5e-20 71.7 1.0 5.4 3 2 1 5 5 5 2 LicD family SecY PF00344.20 KSA02650.1 - 2.2e-67 227.5 11.2 2.8e-67 227.1 11.2 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 KSA02650.1 - 1.2e-17 63.4 0.2 4.4e-17 61.6 0.2 2.1 1 0 0 1 1 1 1 Plug domain of Sec61p QCR10 PF09796.9 KSA02650.1 - 0.11 12.6 0.4 1.1 9.4 0.1 2.8 3 0 0 3 3 3 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) FBPase PF00316.20 KSA02652.1 - 8.3e-81 270.0 0.6 1.1e-80 269.6 0.6 1.2 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Inositol_P PF00459.25 KSA02652.1 - 0.0094 15.5 0.0 0.012 15.1 0.0 1.2 1 0 0 1 1 1 1 Inositol monophosphatase family MFS_1 PF07690.16 KSA02653.1 - 6.2e-11 41.8 7.2 6.2e-11 41.8 7.2 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF957 PF06117.11 KSA02653.1 - 0.029 13.9 0.1 0.06 12.9 0.1 1.4 1 0 0 1 1 1 0 Enterobacterial protein of unknown function (DUF957) RabGAP-TBC PF00566.18 KSA02654.1 - 0.0043 16.7 8.1 0.036 13.7 0.3 3.6 3 1 1 4 4 4 2 Rab-GTPase-TBC domain RRM_1 PF00076.22 KSA02655.1 - 6.6e-23 80.3 0.1 6.1e-16 58.0 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KSA02655.1 - 0.093 12.7 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif FAM91_C PF14648.6 KSA02655.1 - 0.14 10.9 5.1 0.21 10.4 5.1 1.3 1 0 0 1 1 1 0 FAM91 C-terminus DDHD PF02862.17 KSA02655.1 - 0.62 10.2 5.5 0.74 9.9 1.6 2.2 2 0 0 2 2 2 0 DDHD domain Cellulose_synt PF03552.14 KSA02655.1 - 0.73 8.2 4.7 1 7.8 4.7 1.1 1 0 0 1 1 1 0 Cellulose synthase FHIPEP PF00771.20 KSA02655.1 - 1.7 7.0 3.3 2.2 6.6 3.3 1.1 1 0 0 1 1 1 0 FHIPEP family Eisosome1 PF12757.7 KSA02656.1 - 8.4e-14 51.9 2.5 8.4e-14 51.9 2.5 9.3 5 3 3 9 9 9 1 Eisosome protein 1 DivIC PF04977.15 KSA02656.1 - 0.19 11.5 0.1 0.19 11.5 0.1 10.3 5 2 4 10 10 10 0 Septum formation initiator Kelch_1 PF01344.25 KSA02657.1 - 7.3e-10 38.3 0.2 0.00013 21.5 0.1 3.8 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 KSA02657.1 - 6.1e-08 32.5 0.4 0.0038 17.2 0.0 3.7 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_3 PF13415.6 KSA02657.1 - 2.3e-07 30.9 0.0 0.0003 21.0 0.0 3.8 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_5 PF13854.6 KSA02657.1 - 1.1e-06 28.5 0.1 0.0087 16.0 0.0 3.2 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.6 KSA02657.1 - 0.00026 21.2 4.6 0.046 14.0 0.1 4.9 4 1 0 4 4 4 1 Kelch motif Kelch_2 PF07646.15 KSA02657.1 - 2.8 8.1 8.2 10 6.3 0.3 4.9 6 1 0 6 6 6 0 Kelch motif Aldo_ket_red PF00248.21 KSA02658.1 - 8.5e-55 186.0 0.7 6.5e-53 179.8 0.7 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Hexapep_2 PF14602.6 KSA02659.1 - 3.6e-13 49.0 6.8 1.4e-11 43.9 1.6 3.1 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.24 KSA02659.1 - 2.5e-11 42.8 7.5 2.6e-10 39.6 2.8 3.2 3 0 0 3 3 3 1 Bacterial transferase hexapeptide (six repeats) Mac PF12464.8 KSA02659.1 - 2.1e-06 27.9 0.5 3.5e-06 27.2 0.5 1.4 1 0 0 1 1 1 1 Maltose acetyltransferase Yip1 PF04893.17 KSA02660.1 - 1.8e-10 40.8 20.2 2.9e-10 40.2 20.2 1.2 1 0 0 1 1 1 1 Yip1 domain Anp1 PF03452.14 KSA02661.1 - 2.1e-117 391.2 0.0 2.6e-117 390.9 0.0 1.1 1 0 0 1 1 1 1 Anp1 PGM_PMM_I PF02878.16 KSA02662.1 - 2.6e-35 121.1 0.3 2.5e-32 111.5 0.3 2.5 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 KSA02662.1 - 2.1e-19 70.0 0.0 9.2e-19 68.0 0.0 2.1 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 KSA02662.1 - 9.2e-17 61.3 0.0 1.7e-16 60.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 KSA02662.1 - 0.00011 22.3 0.0 0.00029 21.0 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Prp19 PF08606.11 KSA02663.1 - 5.8e-31 106.3 1.9 1.1e-30 105.4 1.9 1.5 1 0 0 1 1 1 1 Prp19/Pso4-like U-box PF04564.15 KSA02663.1 - 7.6e-06 26.0 0.4 2.6e-05 24.3 0.0 2.0 2 0 0 2 2 2 1 U-box domain ANAPC4_WD40 PF12894.7 KSA02663.1 - 2.2e-05 24.7 0.7 0.025 14.9 0.0 3.6 1 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Agglutinin PF07468.11 KSA02663.1 - 0.028 14.6 0.2 0.064 13.5 0.2 1.6 1 0 0 1 1 1 0 Agglutinin domain HPS3_N PF14761.6 KSA02663.1 - 0.051 13.1 0.2 0.91 9.0 0.0 2.4 2 1 0 2 2 2 0 Hermansky-Pudlak syndrome 3 Lipase PF00151.19 KSA02663.1 - 0.074 12.3 0.0 0.19 11.0 0.0 1.8 2 0 0 2 2 2 0 Lipase zf-Nse PF11789.8 KSA02663.1 - 0.095 12.5 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Metal_resist PF13801.6 KSA02663.1 - 0.48 10.6 5.2 0.79 9.9 5.2 1.2 1 0 0 1 1 1 0 Heavy-metal resistance SUR7 PF06687.12 KSA02664.1 - 2.2e-71 239.9 12.3 2.6e-71 239.6 12.3 1.1 1 0 0 1 1 1 1 SUR7/PalI family Adeno_Penton_B PF01686.17 KSA02664.1 - 0.056 11.9 0.0 0.062 11.8 0.0 1.1 1 0 0 1 1 1 0 Adenovirus penton base protein Yip1 PF04893.17 KSA02664.1 - 6.3 6.5 15.9 3.8 7.2 10.6 2.6 2 1 0 2 2 2 0 Yip1 domain NIF PF03031.18 KSA02665.1 - 3e-25 88.8 0.1 1.1e-24 86.9 0.0 2.1 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase BRCT PF00533.26 KSA02665.1 - 2.3e-08 34.3 0.3 9.4e-08 32.3 0.1 2.2 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KSA02665.1 - 0.00066 19.6 0.2 0.0044 16.9 0.0 2.5 2 1 0 2 2 2 1 twin BRCT domain BRCT_2 PF16589.5 KSA02665.1 - 0.0035 17.7 0.0 0.0098 16.3 0.0 1.8 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Sigma70_ner PF04546.13 KSA02665.1 - 7.4 6.4 32.6 1.8 8.4 1.4 3.5 3 0 0 3 3 3 0 Sigma-70, non-essential region TAF8_C PF10406.9 KSA02666.1 - 1.5e-17 63.9 2.0 1.5e-17 63.9 2.0 3.8 3 0 0 3 3 3 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.13 KSA02666.1 - 0.034 14.2 0.0 0.075 13.0 0.0 1.5 1 0 0 1 1 1 0 Bromodomain associated CwfJ_C_2 PF04676.14 KSA02666.1 - 0.52 11.2 4.5 0.46 11.4 0.2 2.9 2 0 0 2 2 2 0 Protein similar to CwfJ C-terminus 2 ubiquitin PF00240.23 KSA02667.1 - 2.4e-23 81.7 0.2 3.5e-23 81.1 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KSA02667.1 - 3e-12 46.2 0.0 4.7e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA PF00627.31 KSA02667.1 - 3e-08 33.4 1.7 1e-07 31.7 0.1 2.4 2 0 0 2 2 2 1 UBA/TS-N domain DUF2407 PF10302.9 KSA02667.1 - 6e-06 26.8 0.1 1.1e-05 25.9 0.1 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 KSA02667.1 - 8.9e-06 25.8 0.2 1.6e-05 25.0 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KSA02667.1 - 0.0013 19.1 0.1 0.0032 17.9 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 KSA02667.1 - 0.017 15.0 0.0 0.031 14.2 0.0 1.3 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain GerD PF17898.1 KSA02667.1 - 0.021 14.8 9.6 0.039 13.9 9.3 1.6 1 1 0 1 1 1 0 Spore germination GerD central core domain HOIP-UBA PF16678.5 KSA02667.1 - 0.057 13.4 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 HOIP UBA domain pair Blt1 PF12754.7 KSA02667.1 - 0.08 13.3 0.3 0.13 12.6 0.3 1.4 1 0 0 1 1 1 0 Blt1 N-terminal domain Ubiquitin_4 PF18036.1 KSA02667.1 - 0.2 11.7 0.1 4.2 7.5 0.0 2.2 1 1 1 2 2 2 0 Ubiquitin-like domain STI1 PF17830.1 KSA02667.1 - 0.63 10.0 22.0 2.9 7.9 3.5 2.5 1 1 1 2 2 2 0 STI1 domain XPC-binding PF09280.11 KSA02667.1 - 3 7.6 12.5 1.5e+02 2.2 12.5 2.4 1 1 0 1 1 1 0 XPC-binding domain GATA PF00320.27 KSA02669.1 - 5.3e-08 32.3 5.7 1.5e-07 30.9 5.7 1.8 1 0 0 1 1 1 1 GATA zinc finger ADD_DNMT3 PF17980.1 KSA02669.1 - 0.029 14.3 0.7 0.029 14.3 0.7 1.7 2 0 0 2 2 2 0 Cysteine rich ADD domain in DNMT3 Transgly_assoc PF04226.13 KSA02671.1 - 7.8 6.8 15.5 9.7 6.5 15.5 1.1 1 0 0 1 1 1 0 Transglycosylase associated protein Mtr2 PF10429.9 KSA02672.1 - 2.1e-65 219.6 0.0 2.6e-65 219.3 0.0 1.0 1 0 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 DUF1194 PF06707.11 KSA02672.1 - 0.17 11.1 0.0 0.21 10.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1194) PaRep2b PF07775.11 KSA02673.1 - 0.0085 14.6 0.0 0.012 14.1 0.0 1.1 1 0 0 1 1 1 1 PaRep2b protein 5_nucleotid_C PF02872.18 KSA02673.1 - 0.045 14.0 0.0 0.26 11.5 0.0 2.1 2 0 0 2 2 2 0 5'-nucleotidase, C-terminal domain Ribosomal_S4e PF00900.20 KSA02674.1 - 7.7e-38 128.3 0.9 1.7e-36 124.0 0.3 2.2 2 0 0 2 2 2 1 Ribosomal family S4e 40S_S4_C PF16121.5 KSA02674.1 - 5.8e-23 80.3 0.1 1.2e-22 79.2 0.1 1.6 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 KSA02674.1 - 1.8e-21 75.9 6.4 1.1e-20 73.4 6.4 2.1 2 0 0 2 2 2 1 RS4NT (NUC023) domain S4 PF01479.25 KSA02674.1 - 3.7e-08 32.9 0.0 7.1e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 KSA02674.1 - 1e-05 25.3 2.5 1e-05 25.3 2.5 3.1 3 0 0 3 3 3 1 KOW motif RabGAP-TBC PF00566.18 KSA02675.1 - 7.8e-47 159.7 6.8 7.8e-47 159.7 6.8 3.2 3 1 0 3 3 3 1 Rab-GTPase-TBC domain Pox_A_type_inc PF04508.12 KSA02675.1 - 0.077 12.9 0.5 0.23 11.4 0.5 1.9 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat DUF4201 PF13870.6 KSA02675.1 - 0.29 10.9 21.1 0.094 12.5 2.1 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4201) Wbp11 PF09429.10 KSA02675.1 - 3.3 8.2 20.4 0.29 11.6 3.0 4.1 4 0 0 4 4 4 0 WW domain binding protein 11 Gal4_dimer PF03902.13 KSA02677.1 - 2.2e-09 37.3 0.1 7.1e-09 35.7 0.1 1.9 1 0 0 1 1 1 1 Gal4-like dimerisation domain Zn_clus PF00172.18 KSA02677.1 - 2e-08 34.2 18.4 4.4e-08 33.1 18.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RQC PF09382.10 KSA02678.1 - 5e-26 90.7 0.1 1.7e-25 89.0 0.1 2.0 1 0 0 1 1 1 1 RQC domain Helicase_C PF00271.31 KSA02678.1 - 5.2e-24 84.7 0.4 4.5e-16 59.2 0.0 3.6 3 0 0 3 3 3 2 Helicase conserved C-terminal domain DEAD PF00270.29 KSA02678.1 - 6.6e-24 84.6 0.0 2.1e-23 83.0 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 KSA02678.1 - 1e-17 64.6 8.0 7.1e-17 61.9 8.0 2.6 1 0 0 1 1 1 1 RecQ zinc-binding ResIII PF04851.15 KSA02678.1 - 3.3e-06 27.2 0.0 2.8e-05 24.2 0.0 2.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HRDC PF00570.23 KSA02678.1 - 4.8e-06 26.5 0.0 1.2e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 HRDC domain Helicase_Sgs1 PF11408.8 KSA02678.1 - 0.0034 17.4 0.1 0.012 15.6 0.1 2.0 1 0 0 1 1 1 1 Sgs1 RecQ helicase zf-CCCH PF00642.24 KSA02679.1 - 1.4e-18 66.3 14.6 3.3e-10 39.6 0.8 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KSA02679.1 - 1.3e-07 31.5 20.1 9.7e-06 25.5 1.6 2.5 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 KSA02679.1 - 2.5e-07 30.3 16.7 0.00017 21.3 0.8 2.8 3 0 0 3 3 3 2 CCCH-type zinc finger DUF2408 PF10303.9 KSA02679.1 - 0.00066 20.3 0.5 0.00082 19.9 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2408) TFIIA PF03153.13 KSA02679.1 - 0.0097 15.9 12.7 0.011 15.8 12.7 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 KSA02679.1 - 0.26 10.9 21.5 0.47 10.0 21.5 1.4 1 0 0 1 1 1 0 Spt20 family zf-CCCH_2 PF14608.6 KSA02679.1 - 1.2 9.7 15.3 0.57 10.7 0.9 2.5 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Presenilin PF01080.17 KSA02679.1 - 3.3 6.4 4.9 4.5 5.9 4.9 1.1 1 0 0 1 1 1 0 Presenilin Gcn1_N PF12074.8 KSA02680.1 - 6e-84 282.4 2.2 6e-84 282.4 2.2 3.5 4 0 0 4 4 4 1 Generalcontrol nonderepressible 1 (Gcn1) N-terminal HEAT_EZ PF13513.6 KSA02680.1 - 1.6e-31 108.3 18.4 0.0072 16.8 0.1 14.7 14 2 1 15 15 14 7 HEAT-like repeat HEAT PF02985.22 KSA02680.1 - 8.4e-31 103.4 18.0 0.075 13.3 0.0 17.2 17 0 0 17 17 17 8 HEAT repeat HEAT_2 PF13646.6 KSA02680.1 - 1.9e-23 82.7 18.3 0.00057 20.2 0.2 12.5 9 3 5 14 14 13 7 HEAT repeats CLASP_N PF12348.8 KSA02680.1 - 3e-19 69.5 1.8 0.00037 20.1 0.0 9.5 8 3 2 10 10 10 3 CLASP N terminal Cnd1 PF12717.7 KSA02680.1 - 1.6e-11 44.5 27.5 0.047 13.7 0.1 12.9 7 5 5 13 13 13 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 KSA02680.1 - 2.7e-10 40.7 4.7 0.23 12.1 0.0 10.3 9 2 3 12 12 12 1 Vacuolar 14 Fab1-binding region DUF3385 PF11865.8 KSA02680.1 - 6.1e-05 23.0 3.5 18 5.2 0.0 8.6 8 2 0 8 8 8 0 Domain of unknown function (DUF3385) RIX1 PF08167.12 KSA02680.1 - 0.00099 18.9 1.3 3.4 7.4 0.1 5.2 3 0 0 3 3 3 1 rRNA processing/ribosome biogenesis Tti2 PF10521.9 KSA02680.1 - 0.005 16.4 1.8 1.1 8.8 0.0 4.2 3 0 0 3 3 3 1 Tti2 family RTP1_C1 PF10363.9 KSA02680.1 - 2.2 8.5 7.9 42 4.4 0.0 6.7 7 1 1 8 8 8 0 Required for nuclear transport of RNA pol II C-terminus 1 zf-H2C2_2 PF13465.6 KSA02681.1 - 1.4e-07 31.6 17.6 0.00025 21.3 4.7 3.6 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 KSA02681.1 - 7.6e-07 29.3 16.7 0.0017 18.7 5.8 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KSA02681.1 - 0.0064 17.2 13.6 0.31 12.0 3.8 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KSA02681.1 - 0.21 11.9 2.3 0.39 11.1 0.8 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 KSA02681.1 - 0.33 11.6 0.1 0.33 11.6 0.1 2.5 3 0 0 3 3 3 0 FOXP coiled-coil domain zf-H2C2_5 PF13909.6 KSA02681.1 - 1.9 8.3 12.3 2.4 8.0 0.2 3.7 3 0 0 3 3 3 0 C2H2-type zinc-finger domain RRM_1 PF00076.22 KSA02682.1 - 6.1e-27 93.2 2.8 3.8e-15 55.5 0.2 4.0 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KSA02682.1 - 0.042 14.0 0.2 0.34 11.1 0.0 2.7 2 1 0 2 2 2 0 RNA recognition motif Nup35_RRM_2 PF14605.6 KSA02682.1 - 0.05 13.6 0.0 12 6.0 0.0 3.1 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif JAB PF01398.21 KSA02683.1 - 2.8e-28 98.2 0.2 2.8e-28 98.2 0.2 2.0 3 0 0 3 3 3 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 KSA02683.1 - 3.6e-05 23.5 0.0 7e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain SDA1 PF05285.12 KSA02683.1 - 0.18 11.2 12.8 0.23 10.8 12.8 1.2 1 0 0 1 1 1 0 SDA1 E7 PF00527.18 KSA02683.1 - 0.37 11.0 0.1 0.37 11.0 0.1 1.9 2 0 0 2 2 2 0 E7 protein, Early protein DNA_pol_phi PF04931.13 KSA02683.1 - 2.7 6.0 25.4 1.5 6.9 1.1 2.3 2 0 0 2 2 2 0 DNA polymerase phi UCH PF00443.29 KSA02684.1 - 1.6e-52 178.6 5.4 1.6e-52 178.6 5.4 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KSA02684.1 - 7.3e-16 58.6 6.5 7.4e-15 55.3 6.5 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 KSA02684.1 - 0.16 11.4 3.2 0.48 9.9 0.2 2.9 2 2 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Yippee-Mis18 PF03226.14 KSA02685.1 - 4.1e-13 49.5 1.2 6.5e-13 48.8 1.2 1.3 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Transp_Tc5_C PF04236.15 KSA02685.1 - 0.0027 18.0 1.3 0.12 12.8 0.4 2.3 2 0 0 2 2 2 1 Tc5 transposase C-terminal domain RIG-I_C-RD PF11648.8 KSA02685.1 - 0.0029 17.8 2.7 0.0079 16.4 2.7 1.7 1 1 0 1 1 1 1 C-terminal domain of RIG-I zf-AN1 PF01428.16 KSA02685.1 - 0.014 15.5 1.9 0.12 12.5 0.2 2.1 2 0 0 2 2 2 0 AN1-like Zinc finger Rsm1 PF08600.10 KSA02685.1 - 0.024 14.8 0.3 2.8 8.2 0.0 2.3 2 0 0 2 2 2 0 Rsm1-like DpnI PF06044.12 KSA02685.1 - 0.07 12.8 0.7 0.38 10.4 0.2 2.1 1 1 1 2 2 2 0 Dam-replacing family Ribosomal_S27e PF01667.17 KSA02685.1 - 0.15 11.8 2.1 12 5.7 0.6 2.3 2 0 0 2 2 2 0 Ribosomal protein S27 Ribosomal_L22 PF00237.19 KSA02686.1 - 5e-20 71.7 0.1 1.2e-19 70.4 0.1 1.7 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e RRM_DME PF15628.6 KSA02686.1 - 0.15 12.3 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 RRM in Demeter RAG2_PHD PF13341.6 KSA02687.1 - 0.17 12.0 0.0 0.18 11.9 0.0 1.1 1 0 0 1 1 1 0 RAG2 PHD domain SHR3_chaperone PF08229.11 KSA02688.1 - 1.2e-70 236.3 0.3 1.5e-70 236.0 0.3 1.2 1 0 0 1 1 1 1 ER membrane protein SH3 FixQ PF05545.11 KSA02688.1 - 6.9 6.7 8.1 7.2 6.7 1.2 3.3 2 1 1 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ Ras PF00071.22 KSA02689.1 - 1.1e-52 178.0 0.0 1.5e-52 177.5 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KSA02689.1 - 4.6e-19 68.8 0.0 7.3e-19 68.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KSA02689.1 - 5.4e-06 26.0 0.0 7e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family RRM_1 PF00076.22 KSA02690.1 - 8.2e-09 35.2 0.0 2.1e-08 33.9 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) POT1PC PF16686.5 KSA02690.1 - 0.11 12.4 0.5 0.11 12.4 0.5 2.0 2 1 1 3 3 3 0 ssDNA-binding domain of telomere protection protein CDC45 PF02724.14 KSA02690.1 - 0.49 8.6 6.1 0.64 8.3 6.1 1.2 1 0 0 1 1 1 0 CDC45-like protein SNRNP27 PF08648.12 KSA02691.1 - 6.9e-25 86.9 0.6 1.5e-24 85.8 0.6 1.6 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins WD40 PF00400.32 KSA02692.1 - 6.8e-10 39.4 0.5 0.00013 22.7 0.0 4.7 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KSA02692.1 - 1.8e-06 28.2 0.1 0.079 13.3 0.0 3.4 2 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain adh_short PF00106.25 KSA02693.1 - 2.1e-16 59.9 0.0 4.2e-11 42.7 0.0 2.4 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KSA02693.1 - 5.4e-09 35.9 0.0 1.5e-06 27.9 0.0 2.3 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KSA02693.1 - 1.2e-06 28.6 0.0 2.1e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 KR domain DUF4522 PF15022.6 KSA02693.1 - 1.6 9.0 4.6 2.4 8.4 2.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4522) FANCI_S1-cap PF14674.6 KSA02693.1 - 3.9 7.6 5.8 5.2 7.2 1.8 2.4 2 0 0 2 2 2 0 FANCI solenoid 1 cap Pkinase PF00069.25 KSA02694.1 - 5.5e-50 170.2 0.0 8e-50 169.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KSA02694.1 - 1.8e-23 83.1 0.0 2.8e-23 82.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KSA02694.1 - 0.0053 16.7 0.0 0.0085 16.0 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KSA02694.1 - 0.028 13.4 0.1 0.028 13.4 0.1 2.4 3 0 0 3 3 3 0 Haspin like kinase domain FTA2 PF13095.6 KSA02694.1 - 0.14 11.8 0.3 0.51 9.9 0.1 1.9 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Ribosomal_L11 PF00298.19 KSA02695.1 - 3e-27 94.9 0.6 4.4e-27 94.4 0.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.14 KSA02695.1 - 5.1e-26 90.3 0.3 9.1e-26 89.5 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain WD40 PF00400.32 KSA02697.1 - 9.8e-10 38.9 10.5 7e-05 23.5 0.3 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat GDC-P PF02347.16 KSA02698.1 - 9.5e-193 640.8 0.0 3e-181 603.0 0.0 2.6 3 0 0 3 3 3 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.21 KSA02698.1 - 0.0014 17.9 0.0 0.0027 17.1 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Hydantoinase_B PF02538.14 KSA02699.1 - 4.3e-203 675.4 0.1 5.4e-203 675.1 0.1 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 KSA02699.1 - 9.2e-92 307.4 0.0 4.1e-91 305.3 0.0 2.0 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KSA02699.1 - 4e-54 183.0 0.1 2.4e-52 177.2 0.0 2.3 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region DUF1445 PF07286.12 KSA02700.1 - 2.8e-58 195.9 0.0 3.9e-58 195.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1445) NRD1_2 PF01995.16 KSA02700.1 - 0.011 15.0 0.1 0.15 11.3 0.0 2.1 2 0 0 2 2 2 0 NrpR regulatory domains NRD1 and 2 C8 PF08742.11 KSA02700.1 - 0.16 12.4 0.0 0.34 11.4 0.0 1.6 1 0 0 1 1 1 0 C8 domain MFS_1 PF07690.16 KSA02701.1 - 7.4e-38 130.4 17.9 1.1e-37 129.7 17.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KSA02701.1 - 9.1e-08 31.4 17.8 2.3e-07 30.0 17.1 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter ArsP_1 PF03773.13 KSA02701.1 - 0.00054 19.2 2.0 0.0015 17.7 0.0 2.5 2 1 1 3 3 3 1 Predicted permease Fungal_trans PF04082.18 KSA02702.1 - 1.4e-10 40.7 0.8 1.4e-10 40.7 0.8 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Cyclin PF08613.11 KSA02703.1 - 3.9e-36 124.9 1.0 6.5e-36 124.1 0.2 1.8 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 KSA02703.1 - 0.0061 16.3 0.1 0.013 15.3 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain DNA_pol_phi PF04931.13 KSA02703.1 - 0.29 9.2 21.1 0.13 10.3 17.2 2.0 2 0 0 2 2 2 0 DNA polymerase phi CobT PF06213.12 KSA02703.1 - 0.46 9.8 11.0 0.82 9.0 11.0 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT ABC2_membrane PF01061.24 KSA02704.1 - 4.9e-74 248.3 54.2 3.7e-45 153.9 17.1 2.4 3 0 0 3 3 2 2 ABC-2 type transporter ABC_tran PF00005.27 KSA02704.1 - 8.4e-38 130.0 0.0 5.7e-18 65.7 0.0 2.7 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KSA02704.1 - 6.5e-31 106.1 0.1 3.9e-30 103.6 0.0 2.5 2 0 0 2 2 2 1 CDR ABC transporter ABC_trans_N PF14510.6 KSA02704.1 - 8.3e-12 45.6 0.1 4.2e-11 43.3 0.0 2.2 2 0 0 2 2 2 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 KSA02704.1 - 4.3e-10 39.2 9.8 4.3e-10 39.2 9.8 3.3 2 2 1 3 3 3 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 KSA02704.1 - 4.1e-06 26.8 0.1 0.00028 20.8 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase ABC2_membrane_2 PF12679.7 KSA02704.1 - 9.6e-06 25.1 5.9 9.6e-06 25.1 5.9 2.5 2 1 0 2 2 2 1 ABC-2 family transporter protein SMC_N PF02463.19 KSA02704.1 - 7.9e-05 22.2 0.0 0.099 12.1 0.0 3.4 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KSA02704.1 - 0.00019 21.9 2.5 0.0015 18.9 0.1 2.7 3 0 0 3 3 2 1 AAA ATPase domain MMR_HSR1 PF01926.23 KSA02704.1 - 0.0022 18.1 0.2 0.26 11.4 0.1 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_29 PF13555.6 KSA02704.1 - 0.003 17.3 0.6 0.24 11.1 0.2 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.6 KSA02704.1 - 0.0045 16.8 0.0 4 7.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system NACHT PF05729.12 KSA02704.1 - 0.01 15.8 0.1 0.048 13.6 0.0 2.2 2 0 0 2 2 2 0 NACHT domain cobW PF02492.19 KSA02704.1 - 0.01 15.4 0.6 0.022 14.3 0.3 1.7 2 0 0 2 2 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 KSA02704.1 - 0.013 15.8 2.2 0.013 15.7 0.1 2.2 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KSA02704.1 - 0.013 15.1 0.1 0.053 13.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KSA02704.1 - 0.029 14.9 0.2 0.44 11.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KSA02704.1 - 0.066 13.8 0.0 0.39 11.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 KSA02704.1 - 0.11 12.5 0.4 0.27 11.2 0.1 1.7 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 KSA02704.1 - 0.19 11.5 1.3 1.1 8.9 0.1 2.7 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.6 KSA02704.1 - 0.19 11.9 0.2 0.69 10.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain ABC_ATPase PF09818.9 KSA02704.1 - 0.2 10.4 0.4 0.34 9.7 0.4 1.3 1 0 0 1 1 1 0 Predicted ATPase of the ABC class AAA_30 PF13604.6 KSA02704.1 - 0.22 11.3 0.5 2.6 7.7 0.1 2.2 2 0 0 2 2 2 0 AAA domain RgpF PF05045.12 KSA02704.1 - 0.35 9.6 4.9 0.11 11.3 1.2 1.8 2 0 0 2 2 2 0 Rhamnan synthesis protein F Dynamin_N PF00350.23 KSA02704.1 - 0.4 10.7 1.3 4.5 7.3 0.0 2.8 3 0 0 3 3 3 0 Dynamin family Metallophos PF00149.28 KSA02705.1 - 2.5e-39 135.9 1.1 4.2e-39 135.2 1.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KSA02705.1 - 1.6e-17 63.6 0.3 3.6e-17 62.5 0.3 1.6 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain tRNA-synt_2c PF01411.19 KSA02706.1 - 5e-222 738.3 0.0 8.6e-222 737.5 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 KSA02706.1 - 9.5e-19 67.2 0.4 3.1e-18 65.6 0.4 2.0 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 KSA02706.1 - 6.9e-16 58.9 4.6 6.9e-16 58.9 4.6 2.2 2 0 0 2 2 2 1 DHHA1 domain GSIII_N PF12437.8 KSA02706.1 - 0.074 12.7 0.1 0.19 11.4 0.1 1.6 1 0 0 1 1 1 0 Glutamine synthetase type III N terminal Copper-fist PF00649.18 KSA02707.1 - 1.1e-18 66.5 1.8 1.1e-18 66.5 1.8 2.3 2 0 0 2 2 2 1 Copper fist DNA binding domain HSF_DNA-bind PF00447.17 KSA02708.1 - 4.5e-30 104.1 2.6 4.5e-30 104.1 2.6 2.6 3 0 0 3 3 3 1 HSF-type DNA-binding Fungal_trans_2 PF11951.8 KSA02709.1 - 1.1e-32 113.4 1.4 2e-32 112.5 1.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KSA02709.1 - 5.7e-07 29.6 13.1 1.2e-06 28.5 13.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SpoIIE PF07228.12 KSA02709.1 - 0.098 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) K_oxygenase PF13434.6 KSA02710.1 - 5.9e-05 22.4 0.0 0.0004 19.6 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KSA02710.1 - 0.00011 21.5 0.0 0.0095 15.2 0.0 3.0 2 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DUF3201 PF11447.8 KSA02710.1 - 0.0071 15.9 0.0 0.019 14.5 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3201) Pyr_redox_3 PF13738.6 KSA02710.1 - 0.02 14.2 1.9 0.36 10.0 0.0 2.9 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF2639 PF11121.8 KSA02710.1 - 0.1 12.6 1.5 0.42 10.7 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2639) Dak1 PF02733.17 KSA02711.1 - 1.2e-102 343.0 0.2 2.3e-102 342.1 0.0 1.5 2 0 0 2 2 2 1 Dak1 domain Dak2 PF02734.17 KSA02711.1 - 1.6e-51 174.7 0.4 1.6e-51 174.7 0.4 2.0 2 0 0 2 2 2 1 DAK2 domain Fungal_trans_2 PF11951.8 KSA02712.1 - 1.2e-100 337.1 2.1 1.7e-100 336.5 2.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KSA02712.1 - 4.3e-10 39.6 7.2 7.1e-10 38.9 7.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Flocculin_t3 PF13928.6 KSA02713.1 - 8.5e-13 48.6 27.0 8.5e-13 48.6 27.0 3.1 3 1 0 3 3 3 1 Flocculin type 3 repeat SWI-SNF_Ssr4 PF08549.10 KSA02713.1 - 0.88 8.1 11.6 1 7.9 11.6 1.0 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) RIFIN PF02009.16 KSA02713.1 - 4.7 7.0 14.2 5.5 6.8 14.2 1.1 1 0 0 1 1 1 0 Rifin DUF2547 PF10818.8 KSA02713.1 - 8.8 7.3 6.9 0.97 10.4 0.9 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2547) ERO1 PF04137.15 KSA02714.1 - 4.3e-116 388.0 0.1 4.3e-116 388.0 0.1 1.7 2 0 0 2 2 2 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) DEAD PF00270.29 KSA02715.1 - 8.6e-51 172.2 0.0 8.6e-51 172.2 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KSA02715.1 - 1.8e-32 112.0 0.1 2.1e-29 102.1 0.0 3.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain CMS1 PF14617.6 KSA02715.1 - 0.0025 17.2 0.0 0.0025 17.2 0.0 3.4 2 1 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit UTP25 PF06862.12 KSA02715.1 - 0.018 13.8 0.2 0.018 13.8 0.2 3.5 3 1 1 4 4 4 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DDHD PF02862.17 KSA02715.1 - 0.13 12.4 7.9 0.27 11.4 7.9 1.6 1 0 0 1 1 1 0 DDHD domain Tim54 PF11711.8 KSA02715.1 - 0.24 10.2 17.1 0.4 9.4 17.1 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RPOL_N PF14700.6 KSA02715.1 - 0.79 9.0 17.3 1.1 8.5 16.6 1.6 2 0 0 2 2 2 0 DNA-directed RNA polymerase N-terminal AAA_22 PF13401.6 KSA02715.1 - 1 9.6 4.6 1 9.6 1.3 2.6 2 1 0 2 2 2 0 AAA domain ALMT PF11744.8 KSA02715.1 - 8.3 5.1 17.0 17 4.0 17.0 1.5 1 0 0 1 1 1 0 Aluminium activated malate transporter SOBP PF15279.6 KSA02715.1 - 8.7 6.9 12.4 14 6.1 12.4 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein UCH_1 PF13423.6 KSA02717.1 - 2.4e-58 198.2 17.5 3.9e-58 197.5 17.5 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 KSA02717.1 - 3.5e-25 89.5 0.0 9.2e-25 88.1 0.0 1.8 1 0 0 1 1 1 1 Exonuclease UCH PF00443.29 KSA02717.1 - 2.4e-10 40.4 13.0 4.3e-10 39.5 13.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase KGK PF08872.10 KSA02717.1 - 0.076 13.5 2.8 2.9 8.4 0.0 2.8 2 0 0 2 2 2 0 KGK domain TCO89 PF10452.9 KSA02718.1 - 5.8e-17 61.9 67.0 3.1e-09 36.4 8.9 3.3 1 1 1 3 3 3 3 TORC1 subunit TCO89 TA0956 PF11513.8 KSA02718.1 - 0.12 12.6 0.6 0.33 11.2 0.6 1.7 1 0 0 1 1 1 0 Thermoplasma acidophilum protein TA0956 PBP1_TM PF14812.6 KSA02718.1 - 1.2 9.6 5.0 4.1 7.9 5.0 1.9 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ribosomal_L36 PF00444.18 KSA02719.1 - 3.9e-20 71.8 10.8 3.9e-20 71.8 10.8 1.4 2 0 0 2 2 2 1 Ribosomal protein L36 Crust_neurohorm PF01147.17 KSA02719.1 - 0.0077 16.0 1.1 0.011 15.6 1.1 1.2 1 0 0 1 1 1 1 Crustacean CHH/MIH/GIH neurohormone family Adaptin_N PF01602.20 KSA02720.1 - 7.7e-96 321.7 20.7 1.2e-95 321.1 20.7 1.3 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 KSA02720.1 - 5.5e-47 159.7 3.3 1.7e-46 158.1 3.3 1.9 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 KSA02720.1 - 9.6e-33 112.7 0.0 2.2e-32 111.6 0.0 1.7 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 KSA02720.1 - 6e-14 52.2 0.0 6.7e-06 26.4 0.0 5.1 4 1 1 5 5 5 4 HEAT repeats Cnd1 PF12717.7 KSA02720.1 - 7.7e-10 39.1 23.1 0.00016 21.7 1.0 5.8 4 1 2 7 7 7 3 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 KSA02720.1 - 0.12 12.6 1.1 7.2 6.8 0.4 3.4 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT PF02985.22 KSA02720.1 - 0.15 12.4 5.2 63 4.2 0.0 5.9 7 0 0 7 7 7 0 HEAT repeat Man-6-P_recep PF02157.15 KSA02721.1 - 5.4e-13 48.6 0.2 5.4e-13 48.6 0.2 1.5 2 0 0 2 2 2 1 Mannose-6-phosphate receptor CIMR PF00878.18 KSA02721.1 - 1.8e-09 37.8 1.0 0.00019 21.6 0.2 2.2 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat ATG27 PF09451.10 KSA02721.1 - 2.1e-08 34.3 0.3 2.3e-07 30.9 0.1 2.0 2 0 0 2 2 2 1 Autophagy-related protein 27 SVM_signal PF12113.8 KSA02721.1 - 0.7 9.8 3.8 6.1 6.8 0.1 2.4 2 0 0 2 2 2 0 SVM protein signal sequence DIL PF01843.19 KSA02722.1 - 2.4e-21 75.9 4.8 4.6e-20 71.8 3.6 3.0 2 1 0 2 2 2 1 DIL domain Ank_2 PF12796.7 KSA02722.1 - 2.3e-08 34.5 0.0 7.3e-08 32.9 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KSA02722.1 - 7.3e-07 29.3 0.1 1.9e-06 28.0 0.1 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KSA02722.1 - 2.4e-06 27.5 0.4 7e-05 22.9 0.1 3.3 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 KSA02722.1 - 9.6e-06 26.1 0.3 7.2e-05 23.3 0.0 2.6 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 KSA02722.1 - 3.3e-05 24.1 0.1 0.00032 21.0 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat Asp PF00026.23 KSA02723.1 - 9.2e-70 235.5 8.2 1.3e-67 228.5 8.2 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KSA02723.1 - 2.1e-13 50.9 1.6 2.1e-13 50.9 1.6 2.2 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.6 KSA02723.1 - 0.02 15.4 0.4 14 6.3 0.1 4.0 2 2 0 2 2 2 0 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 KSA02723.1 - 0.083 12.7 0.0 0.49 10.2 0.0 2.1 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal Ribosomal_L37 PF08561.10 KSA02724.1 - 1.3e-20 74.1 7.6 7.6e-18 65.2 0.8 2.2 1 1 1 2 2 2 2 Mitochondrial ribosomal protein L37 YchF-GTPase_C PF06071.13 KSA02725.1 - 4.6e-35 119.7 0.8 9.4e-35 118.7 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 KSA02725.1 - 3.9e-17 62.4 0.0 4.5e-16 58.9 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KSA02725.1 - 0.0057 16.2 0.0 0.015 14.9 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B TGS PF02824.21 KSA02725.1 - 0.014 15.5 0.0 0.04 14.0 0.0 1.7 1 0 0 1 1 1 0 TGS domain SecA_PP_bind PF01043.20 KSA02725.1 - 0.35 11.5 1.5 1.2 9.8 0.1 2.2 2 0 0 2 2 2 0 SecA preprotein cross-linking domain Mannosyl_trans3 PF11051.8 KSA02726.1 - 1.7e-79 267.0 1.9 3.7e-79 265.9 1.9 1.6 1 0 0 1 1 1 1 Mannosyltransferase putative Glyco_transf_8 PF01501.20 KSA02726.1 - 0.0054 16.3 2.1 0.011 15.3 1.1 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 8 Methyltransf_25 PF13649.6 KSA02727.1 - 1.9e-12 47.7 0.0 3.4e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KSA02727.1 - 8.6e-12 45.6 0.0 1.5e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KSA02727.1 - 4.6e-08 32.7 0.0 7.9e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family RrnaAD PF00398.20 KSA02727.1 - 0.00055 19.1 0.0 0.0048 16.0 0.0 2.1 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase Methyltransf_12 PF08242.12 KSA02727.1 - 0.0014 19.3 0.0 0.0029 18.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.12 KSA02727.1 - 0.034 13.6 0.0 0.061 12.8 0.0 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Methyltransf_23 PF13489.6 KSA02727.1 - 0.066 13.0 0.0 0.086 12.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 KSA02727.1 - 0.17 11.7 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain RPM2 PF08579.11 KSA02728.1 - 6e-37 126.7 4.8 6e-37 126.7 4.8 7.1 7 2 1 8 8 8 2 Mitochondrial ribonuclease P subunit (RPM2) DUF5344 PF17279.2 KSA02728.1 - 2.7 8.6 11.3 2.5 8.8 0.1 5.3 4 0 0 4 4 4 0 Family of unknown function (DUF5344) F-box-like PF12937.7 KSA02729.1 - 3.9e-12 45.9 0.6 7.2e-12 45.0 0.6 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KSA02729.1 - 1e-11 44.4 0.7 2.4e-11 43.2 0.7 1.7 1 0 0 1 1 1 1 F-box domain UIM PF02809.20 KSA02729.1 - 0.019 14.9 0.3 0.019 14.9 0.3 3.2 3 0 0 3 3 3 0 Ubiquitin interaction motif F-box_4 PF15966.5 KSA02729.1 - 0.048 13.6 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 F-box Kelch_5 PF13854.6 KSA02729.1 - 0.11 12.5 0.1 0.3 11.1 0.1 1.7 1 0 0 1 1 1 0 Kelch motif CLU_N PF15044.6 KSA02730.1 - 1.3e-22 79.9 0.9 1.3e-22 79.9 0.9 2.3 3 0 0 3 3 3 1 Mitochondrial function, CLU-N-term Topoisom_I_N PF02919.15 KSA02730.1 - 0.076 12.5 0.3 0.1 12.1 0.3 1.2 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment CLU PF13236.6 KSA02731.1 - 3.4e-77 259.2 0.1 1.3e-76 257.3 0.0 2.1 2 0 0 2 2 2 1 Clustered mitochondria eIF3_p135 PF12807.7 KSA02731.1 - 1.3e-52 178.4 1.5 2.6e-52 177.4 0.1 2.3 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 KSA02731.1 - 9.6e-18 64.3 0.2 1.5e-09 38.0 0.0 3.4 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 KSA02731.1 - 2.1e-09 37.0 2.0 0.036 13.9 0.0 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 KSA02731.1 - 0.02 15.0 3.8 4.3 7.7 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 KSA02731.1 - 0.25 11.6 6.9 29 5.2 0.8 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Cytomega_UL84 PF06284.11 KSA02731.1 - 0.32 9.4 6.6 0.51 8.7 6.6 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Cation_efflux PF01545.21 KSA02732.1 - 9.1e-42 143.1 11.3 3.4e-41 141.2 11.3 1.8 1 1 0 1 1 1 1 Cation efflux family GP4 PF03010.14 KSA02732.1 - 0.12 12.3 0.1 0.12 12.3 0.1 2.1 2 0 0 2 2 2 0 GP4 zf-CCCH PF00642.24 KSA02733.1 - 8.2e-11 41.5 10.1 7.1e-06 25.8 1.0 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KSA02733.1 - 6.8e-06 26.0 13.1 0.0025 17.8 2.0 2.5 2 0 0 2 2 2 2 Zinc finger domain Torus PF16131.5 KSA02733.1 - 1.2e-05 26.0 1.4 0.014 16.1 0.1 2.5 2 0 0 2 2 2 2 Torus domain RRM_1 PF00076.22 KSA02733.1 - 3.7e-05 23.4 0.0 7.7e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_3 PF15663.5 KSA02733.1 - 0.00086 19.5 2.5 0.049 13.9 0.6 2.4 2 0 0 2 2 2 2 Zinc-finger containing family zf-CCCH_4 PF18044.1 KSA02733.1 - 0.33 10.8 14.2 0.34 10.8 1.3 2.6 2 1 0 2 2 2 0 CCCH-type zinc finger Aldo_ket_red PF00248.21 KSA02734.1 - 5.3e-48 163.7 0.0 6e-48 163.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family SAPI PF16560.5 KSA02734.1 - 0.068 12.7 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Putative mobile pathogenicity island NAD_binding_1 PF00175.21 KSA02735.1 - 6.3e-29 100.8 0.0 9.7e-29 100.2 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KSA02735.1 - 1.1e-27 96.3 0.0 1.7e-27 95.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KSA02735.1 - 2.1e-06 28.0 0.0 5.2e-05 23.4 0.0 2.2 1 1 1 2 2 2 1 Ferric reductase NAD binding domain Tubulin PF00091.25 KSA02736.1 - 1.1e-66 224.8 0.0 1.7e-66 224.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KSA02736.1 - 3e-50 169.6 0.1 4.8e-50 169.0 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Ish1 PF10281.9 KSA02737.1 - 2.7e-37 126.7 40.2 1.9e-06 28.1 0.3 8.2 7 0 0 7 7 7 7 Putative stress-responsive nuclear envelope protein HeH PF12949.7 KSA02737.1 - 3.5e-09 36.2 2.0 0.079 12.7 0.3 4.7 4 0 0 4 4 4 3 HeH/LEM domain SAP PF02037.27 KSA02737.1 - 4.2e-09 35.9 0.0 0.073 12.9 0.0 6.4 6 0 0 6 6 6 2 SAP domain Apolipoprotein PF01442.18 KSA02737.1 - 3.6e-06 27.0 21.0 0.00037 20.4 1.2 3.3 3 1 1 4 4 4 2 Apolipoprotein A1/A4/E domain SCNM1_acidic PF15805.5 KSA02737.1 - 0.0099 15.6 0.6 0.0099 15.6 0.6 2.5 2 0 0 2 2 2 1 Acidic C-terminal region of sodium channel modifier 1 SCNM1 Sep15_SelM PF08806.11 KSA02737.1 - 0.051 13.7 4.5 18 5.6 0.0 4.3 5 0 0 5 5 5 0 Sep15/SelM redox domain CRISPR_Cas2 PF09827.9 KSA02737.1 - 0.057 13.6 0.0 0.41 10.9 0.0 2.5 2 0 0 2 2 2 0 CRISPR associated protein Cas2 Mut7-C PF01927.16 KSA02737.1 - 0.066 13.3 0.0 4.8 7.3 0.0 2.7 2 0 0 2 2 2 0 Mut7-C RNAse domain HMG_CoA_synt_C PF08540.10 KSA02738.1 - 5.1e-114 380.6 5.7 6.4e-114 380.3 5.7 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 KSA02738.1 - 7.1e-96 319.1 1.0 1.3e-95 318.1 1.0 1.5 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal ALO PF04030.14 KSA02739.1 - 3.7e-107 358.0 0.6 7.5e-106 353.7 0.2 2.0 2 0 0 2 2 2 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 KSA02739.1 - 4.2e-23 81.6 0.1 8.3e-23 80.7 0.1 1.5 1 1 0 1 1 1 1 FAD binding domain Utp14 PF04615.13 KSA02740.1 - 1.5e-202 675.3 95.9 1.5e-202 675.3 95.9 2.0 1 1 1 2 2 2 1 Utp14 protein Proteasome PF00227.26 KSA02741.1 - 7.6e-58 195.1 0.0 1.1e-57 194.7 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KSA02741.1 - 1.1e-10 40.9 0.8 2.7e-10 39.7 0.0 2.0 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature ABC_tran PF00005.27 KSA02742.1 - 1.4e-49 168.1 0.8 3.8e-27 95.5 0.0 4.5 3 3 1 4 4 2 2 ABC transporter AAA_21 PF13304.6 KSA02742.1 - 4.9e-15 56.1 0.3 0.00053 19.9 0.1 4.7 3 1 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KSA02742.1 - 1.5e-10 40.9 0.0 0.0061 16.0 0.0 3.7 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KSA02742.1 - 2.4e-09 38.0 3.0 0.00046 20.7 0.0 3.4 3 0 0 3 3 3 2 AAA domain Chromo PF00385.24 KSA02742.1 - 2.9e-09 36.7 2.8 6.6e-09 35.5 2.8 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_29 PF13555.6 KSA02742.1 - 7.7e-08 32.0 0.1 0.0067 16.1 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KSA02742.1 - 8.1e-07 29.1 0.0 0.035 14.2 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KSA02742.1 - 2.1e-06 27.8 0.1 0.015 15.2 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_18 PF13238.6 KSA02742.1 - 1e-05 26.1 0.2 0.1 13.1 0.0 4.0 3 1 0 3 3 3 1 AAA domain AAA_15 PF13175.6 KSA02742.1 - 1.2e-05 25.3 0.5 0.055 13.2 0.0 3.0 3 0 0 3 3 2 2 AAA ATPase domain AAA_22 PF13401.6 KSA02742.1 - 3.1e-05 24.3 0.0 0.35 11.1 0.0 2.9 2 0 0 2 2 2 2 AAA domain MeaB PF03308.16 KSA02742.1 - 4.6e-05 22.5 0.1 0.18 10.7 0.0 2.3 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_28 PF13521.6 KSA02742.1 - 0.00015 22.0 0.0 0.053 13.8 0.0 3.3 4 0 0 4 4 3 1 AAA domain DUF87 PF01935.17 KSA02742.1 - 0.00033 20.8 3.2 0.02 15.0 0.0 3.6 4 0 0 4 4 3 1 Helicase HerA, central domain RNA_helicase PF00910.22 KSA02742.1 - 0.00033 21.0 0.1 0.59 10.5 0.0 2.9 2 0 0 2 2 2 1 RNA helicase AAA_16 PF13191.6 KSA02742.1 - 0.00034 21.1 0.2 0.038 14.4 0.0 2.9 3 0 0 3 3 2 1 AAA ATPase domain AAA_27 PF13514.6 KSA02742.1 - 0.00081 19.0 0.0 0.78 9.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KSA02742.1 - 0.0023 17.7 0.7 1 9.0 0.1 3.0 2 1 1 3 3 3 1 AAA domain AAA PF00004.29 KSA02742.1 - 0.0035 17.8 0.0 2.7 8.4 0.0 3.4 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) KAP_NTPase PF07693.14 KSA02742.1 - 0.0036 16.6 0.0 0.0081 15.4 0.0 1.6 1 0 0 1 1 1 1 KAP family P-loop domain AAA_13 PF13166.6 KSA02742.1 - 0.005 15.6 2.0 1.4 7.5 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.6 KSA02742.1 - 0.0052 16.9 0.1 3 8.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KSA02742.1 - 0.0071 16.3 0.0 3.4 7.6 0.0 2.6 2 0 0 2 2 2 1 NACHT domain Thymidylate_kin PF02223.17 KSA02742.1 - 0.011 15.5 0.3 0.088 12.5 0.0 2.4 2 0 0 2 2 2 0 Thymidylate kinase DUF815 PF05673.13 KSA02742.1 - 0.012 14.7 0.4 0.87 8.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NTPase_1 PF03266.15 KSA02742.1 - 0.016 15.1 0.3 2.6 8.0 0.0 3.2 4 0 0 4 4 3 0 NTPase AAA_24 PF13479.6 KSA02742.1 - 0.025 14.3 0.2 1.3 8.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KSA02742.1 - 0.028 13.7 0.3 2.5 7.3 0.0 2.7 3 0 0 3 3 2 0 Zeta toxin TsaE PF02367.17 KSA02742.1 - 0.03 14.3 0.1 8.7 6.4 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 KSA02742.1 - 0.05 13.6 0.0 2.5 8.2 0.0 3.2 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 KSA02742.1 - 0.054 13.4 0.1 1.9 8.4 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain IFRD PF05004.13 KSA02742.1 - 0.056 12.5 2.4 0.5 9.4 0.2 2.6 1 1 1 2 2 2 0 Interferon-related developmental regulator (IFRD) NB-ARC PF00931.22 KSA02742.1 - 0.061 12.5 0.0 6.7 5.8 0.0 2.6 2 0 0 2 2 2 0 NB-ARC domain Roc PF08477.13 KSA02742.1 - 0.067 13.4 0.0 8.7 6.6 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 KSA02742.1 - 0.094 12.3 0.8 16 5.0 0.0 3.4 4 0 0 4 4 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 KSA02742.1 - 0.1 12.1 0.1 3.2 7.2 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Ploopntkinase3 PF18751.1 KSA02742.1 - 0.12 12.3 0.0 18 5.2 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 Exo_endo_phos PF03372.23 KSA02743.1 - 5.9e-06 26.0 0.0 4.4e-05 23.1 0.0 2.2 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RAI1 PF08652.11 KSA02744.1 - 7.7e-05 22.8 0.0 0.0002 21.4 0.0 1.8 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease TPR_1 PF00515.28 KSA02745.1 - 1.4e-09 37.4 0.7 0.00032 20.4 0.2 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KSA02745.1 - 1.1e-08 34.5 0.6 0.00034 20.5 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KSA02745.1 - 7.8e-06 26.3 0.1 1.6e-05 25.3 0.1 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 KSA02745.1 - 8e-05 22.9 1.6 0.0086 16.3 0.3 2.8 1 1 1 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 KSA02745.1 - 0.00042 20.3 5.0 0.024 14.8 0.3 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 KSA02745.1 - 0.0024 17.8 0.3 0.23 11.6 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KSA02745.1 - 0.0029 17.6 0.2 0.25 11.4 0.0 2.5 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat DnaJ PF00226.31 KSA02745.1 - 0.0031 17.6 0.0 0.012 15.8 0.0 2.0 1 0 0 1 1 1 1 DnaJ domain DUF309 PF03745.14 KSA02745.1 - 0.042 13.5 0.0 0.097 12.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF309) TPR_10 PF13374.6 KSA02745.1 - 0.064 13.2 0.1 0.28 11.1 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2406 PF10295.9 KSA02746.1 - 6.6e-27 94.0 2.5 8.3e-27 93.7 0.9 2.0 3 0 0 3 3 3 1 Uncharacterised protein (DUF2406) Pkinase PF00069.25 KSA02747.1 - 5e-69 232.6 0.0 6.1e-69 232.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KSA02747.1 - 4.8e-33 114.5 0.0 6.1e-33 114.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KSA02747.1 - 0.00019 20.9 0.3 0.00029 20.2 0.3 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KSA02747.1 - 0.0008 18.4 1.2 0.0012 17.9 1.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 KSA02747.1 - 0.015 14.9 0.2 2.2 7.8 0.1 2.3 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 KSA02747.1 - 0.067 12.5 1.2 0.13 11.5 1.1 1.5 1 1 0 1 1 1 0 Kinase-like APH PF01636.23 KSA02747.1 - 0.12 12.2 0.1 0.41 10.5 0.1 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family EMP24_GP25L PF01105.24 KSA02748.1 - 1.7e-47 161.8 1.1 1.9e-47 161.5 1.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF4793 PF16041.5 KSA02748.1 - 0.026 14.7 0.4 0.086 13.0 0.4 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4793) VPS13_mid_rpt PF16910.5 KSA02748.1 - 0.049 13.0 0.0 5.2 6.4 0.0 2.1 1 1 1 2 2 2 0 Repeating coiled region of VPS13 Aminotran_1_2 PF00155.21 KSA02749.1 - 6.1e-75 252.6 0.0 7e-75 252.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Esterase PF00756.20 KSA02749.1 - 0.021 14.5 0.0 0.038 13.6 0.0 1.5 1 0 0 1 1 1 0 Putative esterase Pas_Saposin PF09016.10 KSA02749.1 - 0.035 14.4 0.2 7.1 7.0 0.0 3.0 3 0 0 3 3 3 0 Pas factor saposin fold DUF1654 PF07867.11 KSA02749.1 - 0.18 11.5 0.2 3.1 7.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1654) Ribosomal_S27e PF01667.17 KSA02750.1 - 1.8e-26 91.6 6.4 1.9e-26 91.5 6.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S27 Metallophos PF00149.28 KSA02751.1 - 1.6e-40 139.8 0.1 2.1e-40 139.4 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KSA02751.1 - 4e-22 78.4 1.1 6.6e-22 77.7 0.6 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Vfa1 PF08432.10 KSA02752.1 - 1.1e-49 169.2 8.3 1.3e-49 169.0 8.3 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 DUF5523 PF17661.1 KSA02752.1 - 0.07 12.8 7.7 0.094 12.4 7.5 1.3 1 1 0 1 1 1 0 Family of unknown function (DUF5523) Peptidase_S74 PF13884.6 KSA02752.1 - 0.34 11.3 4.9 0.43 10.9 0.4 2.3 1 1 1 2 2 2 0 Chaperone of endosialidase Seryl_tRNA_N PF02403.22 KSA02752.1 - 6.8 7.0 10.2 0.77 10.0 5.5 1.8 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain SRPRB PF09439.10 KSA02753.1 - 4.1e-35 120.8 0.8 5e-35 120.6 0.8 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 KSA02753.1 - 4.3e-10 39.3 0.1 8.3e-10 38.4 0.1 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KSA02753.1 - 2.3e-08 34.1 0.1 3.9e-08 33.4 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KSA02753.1 - 9.5e-08 31.8 0.1 8.4e-07 28.7 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 KSA02753.1 - 9e-07 28.9 0.3 6.1e-06 26.2 0.1 1.9 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein Gtr1_RagA PF04670.12 KSA02753.1 - 1.3e-05 24.7 0.8 2.1e-05 24.0 0.8 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 KSA02753.1 - 0.00048 19.7 0.1 0.0012 18.4 0.1 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_21 PF13304.6 KSA02753.1 - 0.00061 19.7 3.5 0.085 12.7 3.5 2.2 1 1 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system Ras PF00071.22 KSA02753.1 - 0.0022 17.6 0.1 0.0033 17.0 0.1 1.3 1 0 0 1 1 1 1 Ras family DUF928 PF06051.12 KSA02753.1 - 0.012 15.5 0.4 0.022 14.6 0.1 1.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF928) Roc PF08477.13 KSA02753.1 - 0.02 15.1 0.0 0.037 14.2 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 KSA02753.1 - 0.033 14.7 13.5 1.6 9.2 13.5 2.2 1 1 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 KSA02753.1 - 0.076 13.1 2.8 0.081 13.0 0.1 2.2 2 1 1 3 3 3 0 Dynamin family Chorismate_synt PF01264.21 KSA02754.1 - 4.5e-139 462.7 0.0 5.2e-139 462.5 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase Kelch_6 PF13964.6 KSA02755.1 - 8.9e-06 25.8 3.1 0.006 16.8 0.1 4.3 4 0 0 4 4 4 1 Kelch motif Kelch_3 PF13415.6 KSA02755.1 - 0.0023 18.2 0.7 0.36 11.2 0.0 3.7 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_4 PF13418.6 KSA02755.1 - 0.0028 17.6 3.7 0.12 12.4 0.0 3.9 3 1 0 3 3 3 1 Galactose oxidase, central domain Gram_pos_anchor PF00746.21 KSA02755.1 - 0.085 12.8 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 LPXTG cell wall anchor motif TFIIE-A_C PF11521.8 KSA02755.1 - 3.6 8.0 7.7 1.5 9.1 4.5 2.1 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha zf-C2H2 PF00096.26 KSA02756.1 - 1.2e-09 38.0 16.3 0.00011 22.4 2.7 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KSA02756.1 - 1.4e-06 28.6 14.6 0.0086 16.8 2.0 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KSA02756.1 - 1.9e-06 28.0 17.4 1.8e-05 25.0 6.7 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 KSA02756.1 - 5.6e-05 23.0 10.9 0.0012 18.8 2.0 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KSA02756.1 - 0.00036 20.7 9.4 0.14 12.5 1.7 3.2 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KSA02756.1 - 0.00057 20.2 10.1 0.012 15.9 2.7 3.1 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-Di19 PF05605.12 KSA02756.1 - 0.00066 19.9 4.1 0.0011 19.2 4.1 1.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding CholecysA-Rec_N PF09193.10 KSA02756.1 - 0.072 13.1 0.2 0.2 11.7 0.2 1.7 1 0 0 1 1 1 0 Cholecystokinin A receptor, N-terminal zf-BED PF02892.15 KSA02756.1 - 0.11 12.5 12.3 2.4 8.2 7.0 2.8 1 1 1 2 2 2 0 BED zinc finger zf-C2H2_2 PF12756.7 KSA02756.1 - 1 9.7 7.7 10 6.6 0.6 2.6 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-MYST PF17772.1 KSA02756.1 - 1.6 8.4 5.1 0.46 10.1 0.5 2.3 2 0 0 2 2 2 0 MYST family zinc finger domain zf-H2C2_5 PF13909.6 KSA02756.1 - 5.6 6.8 10.5 2.5 7.9 0.2 2.5 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 KSA02757.1 - 7.3e-12 45.1 20.8 0.00023 21.4 3.2 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KSA02757.1 - 4.6e-08 33.3 17.7 0.0015 19.2 1.6 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KSA02757.1 - 2e-05 24.8 0.6 2e-05 24.8 0.6 3.8 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 KSA02757.1 - 0.0068 16.4 13.9 0.011 15.7 0.0 3.4 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KSA02757.1 - 0.036 14.4 0.2 0.036 14.4 0.2 3.8 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.18 KSA02757.1 - 1.6 9.5 8.7 0.16 12.7 2.9 2.2 1 1 1 2 2 2 0 TRAF-type zinc finger zf_ZIC PF18366.1 KSA02757.1 - 4.2 7.6 5.0 32 4.8 0.1 3.2 3 0 0 3 3 3 0 Zic proteins zinc finger domain zf-C2HE PF16278.5 KSA02757.1 - 5 7.7 7.0 1.3 9.6 2.0 2.8 2 1 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger 2-oxoacid_dh PF00198.23 KSA02758.1 - 7.3e-77 257.9 0.0 1.1e-76 257.3 0.0 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KSA02758.1 - 1.3e-17 63.3 3.5 3.5e-17 62.0 3.4 1.8 2 0 0 2 2 2 1 Biotin-requiring enzyme GCV_H PF01597.19 KSA02758.1 - 3.2e-06 27.0 0.9 1.2e-05 25.2 0.5 2.1 2 0 0 2 2 2 1 Glycine cleavage H-protein HlyD_3 PF13437.6 KSA02758.1 - 6e-05 23.7 0.8 0.016 15.9 0.3 2.9 2 1 1 3 3 3 1 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 KSA02758.1 - 0.00014 21.6 0.4 0.13 12.1 0.2 2.3 1 1 1 2 2 2 2 Biotin-lipoyl like RnfC_N PF13375.6 KSA02758.1 - 0.0074 16.2 0.3 0.0074 16.2 0.3 2.4 2 1 0 2 2 2 1 RnfC Barrel sandwich hybrid domain HlyD_D23 PF16576.5 KSA02758.1 - 0.14 11.4 0.2 0.14 11.4 0.2 2.2 2 1 0 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion Presenilin PF01080.17 KSA02758.1 - 0.28 9.9 8.8 0.43 9.3 8.8 1.2 1 0 0 1 1 1 0 Presenilin GAGA_bind PF06217.12 KSA02758.1 - 0.44 10.8 9.2 0.59 10.4 9.2 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family RR_TM4-6 PF06459.12 KSA02758.1 - 0.47 10.2 12.4 0.64 9.8 12.4 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 eIF3_subunit PF08597.10 KSA02758.1 - 1.6 8.6 22.1 2.5 8.0 22.1 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit CDC45 PF02724.14 KSA02758.1 - 6 5.0 10.6 7.9 4.6 10.6 1.1 1 0 0 1 1 1 0 CDC45-like protein MARVEL PF01284.23 KSA02759.1 - 0.00027 21.0 14.3 0.00043 20.3 14.3 1.3 1 0 0 1 1 1 1 Membrane-associating domain DUF1240 PF06836.12 KSA02759.1 - 2.1 8.9 7.9 2 9.0 6.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1240) TRP PF06011.12 KSA02761.1 - 4.4e-154 513.3 34.0 5.2e-154 513.1 34.0 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KSA02761.1 - 9.4e-41 139.4 0.3 1.7e-40 138.6 0.3 1.4 1 0 0 1 1 1 1 ML-like domain E1_DerP2_DerF2 PF02221.15 KSA02761.1 - 0.019 15.4 0.0 0.039 14.4 0.0 1.4 1 0 0 1 1 1 0 ML domain Cadherin_C_2 PF16492.5 KSA02761.1 - 0.1 13.4 3.3 2.7 8.8 0.4 3.5 3 0 0 3 3 3 0 Cadherin cytoplasmic C-terminal Phage_holin_2_3 PF16080.5 KSA02761.1 - 0.21 11.4 1.5 0.47 10.3 0.2 2.2 2 0 0 2 2 2 0 Bacteriophage holin family HP1 PI3_PI4_kinase PF00454.27 KSA02762.1 - 8.4e-43 147.0 0.0 2e-40 139.2 0.0 2.8 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 KSA02762.1 - 6.1e-24 84.4 0.0 1.7e-23 83.0 0.0 1.7 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) eIF-6 PF01912.18 KSA02763.1 - 1.1e-82 276.3 0.6 1.3e-82 276.0 0.6 1.1 1 0 0 1 1 1 1 eIF-6 family AAA_2 PF07724.14 KSA02764.1 - 6.9e-46 156.5 2.0 6.5e-44 150.1 0.0 3.6 5 0 0 5 5 3 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 KSA02764.1 - 1.2e-29 102.3 5.5 2.2e-29 101.4 0.8 2.8 2 0 0 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 KSA02764.1 - 2.5e-23 81.9 0.6 9e-23 80.1 0.6 2.0 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 KSA02764.1 - 7.7e-23 81.4 0.1 8.2e-13 48.9 0.1 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KSA02764.1 - 1.7e-14 54.0 0.1 1.9e-08 34.4 0.0 3.5 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) Clp_N PF02861.20 KSA02764.1 - 1.2e-13 50.9 0.7 1.8e-08 34.4 0.1 3.7 3 0 0 3 3 3 2 Clp amino terminal domain, pathogenicity island component Sigma54_activat PF00158.26 KSA02764.1 - 1.7e-12 47.4 0.3 1.2e-06 28.3 0.0 3.4 2 2 0 2 2 2 2 Sigma-54 interaction domain AAA_16 PF13191.6 KSA02764.1 - 6.2e-10 39.7 9.1 1.2e-05 25.8 0.3 4.7 3 2 1 5 5 4 2 AAA ATPase domain AAA_22 PF13401.6 KSA02764.1 - 6.6e-07 29.7 1.1 0.19 12.0 0.3 4.4 2 2 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 KSA02764.1 - 9.6e-07 29.0 1.7 0.084 12.8 0.2 4.1 2 1 1 3 3 3 2 ATPase domain predominantly from Archaea AAA_14 PF13173.6 KSA02764.1 - 1.2e-06 28.6 0.0 0.079 13.0 0.0 3.1 2 0 0 2 2 2 2 AAA domain TniB PF05621.11 KSA02764.1 - 1.9e-05 24.2 0.0 0.0093 15.4 0.0 3.5 2 1 0 2 2 2 1 Bacterial TniB protein AAA_7 PF12775.7 KSA02764.1 - 8.1e-05 22.2 0.0 0.027 14.0 0.0 3.0 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_30 PF13604.6 KSA02764.1 - 0.00022 21.0 0.0 0.0095 15.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KSA02764.1 - 0.00026 20.9 0.1 0.081 12.8 0.0 3.0 3 0 0 3 3 2 1 NACHT domain RsgA_GTPase PF03193.16 KSA02764.1 - 0.00041 20.3 0.1 0.13 12.1 0.0 2.9 2 0 0 2 2 2 1 RsgA GTPase Mg_chelatase PF01078.21 KSA02764.1 - 0.0007 19.0 0.0 2.2 7.6 0.0 3.4 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KSA02764.1 - 0.0021 18.2 0.9 0.37 10.9 0.0 3.8 4 0 0 4 4 3 1 AAA domain TsaE PF02367.17 KSA02764.1 - 0.0031 17.5 0.0 0.17 11.8 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 KSA02764.1 - 0.0033 17.3 0.0 0.21 11.5 0.0 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Roc PF08477.13 KSA02764.1 - 0.0045 17.2 0.0 0.66 10.2 0.0 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_8 PF12780.7 KSA02764.1 - 0.013 14.9 0.7 0.41 9.9 0.5 2.9 2 1 0 2 2 2 0 P-loop containing dynein motor region D4 IstB_IS21 PF01695.17 KSA02764.1 - 0.019 14.7 0.0 1.1 9.0 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein Torsin PF06309.11 KSA02764.1 - 0.02 15.0 0.0 0.074 13.2 0.0 1.9 2 0 0 2 2 1 0 Torsin Zeta_toxin PF06414.12 KSA02764.1 - 0.021 14.1 0.0 0.34 10.2 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin AAA_24 PF13479.6 KSA02764.1 - 0.025 14.3 0.0 8.6 6.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KSA02764.1 - 0.027 14.2 0.1 4.4 7.1 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF815 PF05673.13 KSA02764.1 - 0.029 13.5 2.1 1 8.5 0.2 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF815) PEPCK_ATP PF01293.20 KSA02764.1 - 0.031 13.0 0.0 0.16 10.6 0.0 1.9 2 0 0 2 2 2 0 Phosphoenolpyruvate carboxykinase SRP54 PF00448.22 KSA02764.1 - 0.035 13.7 0.1 2.3 7.8 0.0 3.0 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain APS_kinase PF01583.20 KSA02764.1 - 0.041 13.8 0.1 0.32 10.9 0.0 2.5 3 0 0 3 3 2 0 Adenylylsulphate kinase ABC_tran PF00005.27 KSA02764.1 - 0.043 14.3 0.8 16 6.0 0.0 3.2 3 0 0 3 3 2 0 ABC transporter AAA_19 PF13245.6 KSA02764.1 - 0.073 13.4 3.0 1.3 9.3 0.4 3.9 4 1 0 4 4 3 0 AAA domain NB-ARC PF00931.22 KSA02764.1 - 0.077 12.2 0.1 2.7 7.1 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain AAA_18 PF13238.6 KSA02764.1 - 0.17 12.4 2.0 13 6.4 0.0 3.5 3 1 0 3 3 2 0 AAA domain V_ATPase_I PF01496.19 KSA02764.1 - 2.8 5.8 5.1 5 4.9 5.1 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TEX19 PF15553.6 KSA02765.1 - 0.061 13.3 0.0 0.069 13.1 0.0 1.0 1 0 0 1 1 1 0 Testis-expressed protein 19 Peptidase_M13 PF01431.21 KSA02766.1 - 0.058 13.0 1.2 0.078 12.6 0.4 1.5 1 1 1 2 2 2 0 Peptidase family M13 ArfGap PF01412.18 KSA02767.1 - 2.5e-30 104.9 0.1 2.5e-30 104.9 0.1 1.8 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf UBA PF00627.31 KSA02767.1 - 0.062 13.2 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 UBA/TS-N domain Sugar_tr PF00083.24 KSA02769.1 - 3.2e-113 379.0 25.0 3.7e-113 378.8 25.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KSA02769.1 - 3.8e-22 78.7 31.8 3.8e-22 78.7 31.8 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily VMA21 PF09446.10 KSA02769.1 - 3 8.0 7.0 6.6 6.9 1.2 3.5 3 0 0 3 3 3 0 VMA21-like domain Sugar_tr PF00083.24 KSA02770.1 - 1.8e-115 386.4 21.5 2.1e-115 386.2 21.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KSA02770.1 - 5.8e-22 78.1 27.5 5.8e-22 78.1 27.5 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KSA02771.1 - 3.3e-114 382.2 25.5 4e-114 382.0 25.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KSA02771.1 - 8.1e-20 71.0 36.0 8.1e-20 71.0 36.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily SHR3_chaperone PF08229.11 KSA02771.1 - 0.4 9.6 2.2 0.33 9.9 0.2 1.9 2 0 0 2 2 2 0 ER membrane protein SH3 Mnd1 PF03962.15 KSA02772.1 - 2.5e-14 53.3 1.3 3.7e-14 52.7 0.3 1.9 2 0 0 2 2 2 1 Mnd1 HTH domain SAM_2 PF07647.17 KSA02772.1 - 0.0075 16.4 1.0 0.015 15.4 0.6 1.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) FapA PF03961.13 KSA02772.1 - 0.11 11.1 3.1 0.12 10.9 3.1 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A FlxA PF14282.6 KSA02772.1 - 4.1 7.5 9.7 9.5 6.3 3.8 2.3 2 0 0 2 2 2 0 FlxA-like protein GMC_oxred_N PF00732.19 KSA02773.1 - 8.2e-61 205.9 0.2 1.1e-60 205.5 0.2 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KSA02773.1 - 2.9e-23 83.0 0.1 6.8e-23 81.8 0.0 1.7 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KSA02773.1 - 4.5e-08 32.6 0.0 0.0017 17.5 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KSA02773.1 - 0.0029 17.8 0.0 0.0062 16.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KSA02773.1 - 0.011 15.0 0.1 0.04 13.1 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF1257 PF06868.11 KSA02773.1 - 0.062 13.6 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1257) FAD_binding_3 PF01494.19 KSA02773.1 - 0.22 10.7 0.1 0.37 10.0 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Mss4 PF04421.13 KSA02774.1 - 9.9e-16 57.7 0.1 1.2e-15 57.4 0.1 1.3 1 0 0 1 1 1 1 Mss4 protein zf-C2H2_aberr PF17017.5 KSA02774.1 - 0.073 13.2 0.4 0.11 12.7 0.4 1.4 1 1 0 1 1 1 0 Aberrant zinc-finger APH PF01636.23 KSA02775.1 - 2.9e-35 122.3 0.0 4e-35 121.9 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 KSA02775.1 - 4.8e-07 29.4 0.0 7.5e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.20 KSA02775.1 - 0.00015 21.4 0.0 0.00021 20.9 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.14 KSA02775.1 - 0.00032 20.0 0.0 0.0005 19.4 0.0 1.3 1 0 0 1 1 1 1 Fructosamine kinase DUF1679 PF07914.11 KSA02775.1 - 0.015 14.1 0.1 0.021 13.7 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1679) Pkinase PF00069.25 KSA02775.1 - 0.089 12.1 0.2 3.8 6.8 0.1 2.2 2 0 0 2 2 2 0 Protein kinase domain APH_6_hur PF04655.14 KSA02775.1 - 0.22 10.9 0.0 1.3 8.3 0.0 1.8 1 1 1 2 2 2 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase LRR_4 PF12799.7 KSA02776.1 - 0.045 14.2 29.1 0.18 12.3 2.0 6.2 2 1 3 6 6 6 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KSA02776.1 - 0.058 13.5 13.7 9.1 6.6 0.0 5.7 5 0 0 5 5 5 0 Leucine Rich repeat F-box-like PF12937.7 KSA02776.1 - 0.15 12.0 3.6 3.4 7.6 0.4 2.9 2 1 0 2 2 2 0 F-box-like LRR_8 PF13855.6 KSA02776.1 - 0.2 11.5 19.4 1.3 8.8 0.3 5.7 4 2 2 6 6 6 0 Leucine rich repeat LRR_1 PF00560.33 KSA02776.1 - 0.76 10.6 16.1 35 5.5 0.1 6.5 5 1 0 5 5 5 0 Leucine Rich Repeat Aminotran_1_2 PF00155.21 KSA02777.1 - 2.8e-35 122.2 0.0 3.5e-35 121.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DUF4250 PF14056.6 KSA02777.1 - 0.081 12.9 0.3 1.2 9.1 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4250) cNMP_binding PF00027.29 KSA02778.1 - 2.3e-22 78.8 0.0 1.1e-05 25.3 0.0 5.0 5 0 0 5 5 5 3 Cyclic nucleotide-binding domain Patatin PF01734.22 KSA02778.1 - 6e-20 72.3 1.4 2.2e-19 70.5 1.4 2.1 1 1 0 1 1 1 1 Patatin-like phospholipase DEAD PF00270.29 KSA02779.1 - 2.2e-09 37.4 0.0 2.2e-08 34.1 0.1 2.7 2 1 0 2 2 2 1 DEAD/DEAH box helicase DUF2674 PF10879.8 KSA02779.1 - 0.0083 15.7 2.0 0.033 13.8 0.2 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2674) Alph_Pro_TM PF09608.10 KSA02779.1 - 0.049 13.4 0.6 0.11 12.3 0.6 1.5 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) ParB PF08775.10 KSA02779.1 - 3.5 8.1 19.5 0.081 13.4 7.3 3.2 3 0 0 3 3 3 0 ParB family PIF1 PF05970.14 KSA02780.1 - 7.1e-59 199.8 4.5 4.7e-46 157.6 0.5 2.4 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 KSA02780.1 - 1.7e-19 70.3 0.0 5.3e-19 68.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KSA02780.1 - 1.4e-10 41.6 0.0 3.6e-10 40.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KSA02780.1 - 3.9e-06 27.2 0.1 1.9e-05 25.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KSA02780.1 - 0.00045 20.6 0.1 0.0014 19.1 0.1 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TSGA13 PF14994.6 KSA02780.1 - 0.00088 18.7 0.3 0.0086 15.5 0.0 2.3 2 0 0 2 2 2 1 Testis-specific gene 13 protein AAA_7 PF12775.7 KSA02780.1 - 0.0017 17.9 0.1 0.004 16.7 0.1 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region ATPase_2 PF01637.18 KSA02780.1 - 0.0085 16.0 0.3 0.77 9.6 0.0 2.7 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea UvrD_C_2 PF13538.6 KSA02780.1 - 0.0097 15.7 0.0 0.022 14.6 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain DUF2075 PF09848.9 KSA02780.1 - 0.011 15.0 0.5 0.11 11.7 0.2 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 KSA02780.1 - 0.011 15.6 0.1 0.023 14.6 0.1 1.5 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.6 KSA02780.1 - 0.022 15.2 0.1 0.052 13.9 0.1 1.6 1 0 0 1 1 1 0 AAA ATPase domain Viral_helicase1 PF01443.18 KSA02780.1 - 0.043 13.6 0.6 20 4.8 0.0 3.1 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase T2SSE PF00437.20 KSA02780.1 - 0.045 12.8 0.3 0.084 11.9 0.3 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 KSA02780.1 - 0.084 12.2 0.1 0.17 11.2 0.1 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family ABC_tran PF00005.27 KSA02780.1 - 0.097 13.2 0.7 0.39 11.2 0.3 2.2 1 1 0 1 1 1 0 ABC transporter Mg_chelatase PF01078.21 KSA02780.1 - 0.11 11.8 0.1 0.33 10.3 0.1 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Helicase_RecD PF05127.14 KSA02780.1 - 0.17 11.7 0.6 1.4 8.7 0.6 2.4 1 1 0 1 1 1 0 Helicase Sec39 PF08314.11 KSA02781.1 - 2.2e-65 221.5 15.3 7.4e-65 219.8 15.3 1.7 1 1 0 1 1 1 1 Secretory pathway protein Sec39 MA3 PF02847.17 KSA02781.1 - 0.049 13.6 1.2 0.45 10.5 0.5 3.1 3 0 0 3 3 3 0 MA3 domain TFIIE_alpha PF02002.17 KSA02781.1 - 0.13 12.1 0.2 0.51 10.2 0.2 2.0 1 0 0 1 1 1 0 TFIIE alpha subunit Shikimate_DH PF01488.20 KSA02782.1 - 0.062 13.4 2.4 0.095 12.8 0.2 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DUF1843 PF08898.10 KSA02782.1 - 0.68 10.5 4.1 21 5.7 0.0 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF1843) HALZ PF02183.18 KSA02782.1 - 4.5 7.6 7.8 0.28 11.4 0.9 2.5 3 0 0 3 3 3 0 Homeobox associated leucine zipper LSM PF01423.22 KSA02783.1 - 7.6e-18 64.0 0.0 9.1e-18 63.7 0.0 1.1 1 0 0 1 1 1 1 LSM domain MRP-L47 PF06984.13 KSA02784.1 - 2.1e-15 56.6 0.2 4e-15 55.7 0.2 1.5 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) DUF5595 PF18077.1 KSA02784.1 - 0.067 13.3 4.8 2.4 8.3 0.7 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF5595) AIM5 PF17050.5 KSA02785.1 - 1.3e-12 48.3 0.1 1.7e-12 47.9 0.1 1.2 1 0 0 1 1 1 1 Altered inheritance of mitochondria 5 PBECR4 PF18813.1 KSA02785.1 - 0.017 15.4 0.1 0.019 15.2 0.1 1.1 1 0 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease4 adh_short PF00106.25 KSA02786.1 - 9.8e-27 93.7 0.0 1.2e-26 93.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KSA02786.1 - 1.2e-15 57.8 0.0 1.5e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KSA02786.1 - 9.4e-06 25.7 0.0 2.4e-05 24.3 0.0 1.6 1 1 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 KSA02786.1 - 0.00078 18.8 0.0 0.0012 18.2 0.0 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF2650 PF10853.8 KSA02786.1 - 0.0055 16.4 0.3 0.016 14.9 0.3 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2650) DUF1776 PF08643.10 KSA02786.1 - 0.023 14.0 0.0 0.037 13.4 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) TssR PF17643.1 KSA02786.1 - 0.14 10.1 0.0 0.2 9.5 0.0 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssR Ribosomal_L17 PF01196.19 KSA02787.1 - 9.2e-21 74.6 0.0 1.5e-20 73.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L17 DUF3701 PF12482.8 KSA02787.1 - 0.073 13.1 0.1 0.66 10.1 0.0 2.4 2 1 1 3 3 3 0 Phage integrase protein YtxH PF12732.7 KSA02787.1 - 0.48 11.0 3.9 11 6.6 0.0 2.8 3 0 0 3 3 3 0 YtxH-like protein TMA7 PF09072.10 KSA02788.1 - 2.1e-24 86.1 22.4 2.3e-24 86.0 22.4 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 WH1 PF00568.23 KSA02789.1 - 1.6e-29 102.1 0.0 2.3e-29 101.5 0.0 1.2 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.20 KSA02789.1 - 1.8e-06 27.5 0.7 3.9e-06 26.5 0.7 1.6 1 0 0 1 1 1 1 WH2 motif GCIP PF13324.6 KSA02790.1 - 1.8e-25 90.0 3.5 1.8e-25 90.0 3.5 1.7 1 1 1 2 2 2 1 Grap2 and cyclin-D-interacting Ribul_P_3_epim PF00834.19 KSA02790.1 - 0.031 13.6 0.4 1.3 8.4 0.0 2.2 2 0 0 2 2 2 0 Ribulose-phosphate 3 epimerase family DUF5102 PF17104.5 KSA02790.1 - 0.039 14.0 0.8 0.24 11.4 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5102) Focal_AT PF03623.13 KSA02790.1 - 0.29 11.1 5.9 0.49 10.4 1.4 3.1 3 0 0 3 3 3 0 Focal adhesion targeting region Esterase PF00756.20 KSA02791.1 - 2.3e-49 168.3 0.0 3e-49 167.9 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 KSA02791.1 - 3.8e-07 29.8 0.1 6.7e-07 29.0 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KSA02791.1 - 0.00019 20.8 0.0 0.00024 20.4 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 UPF0227 PF05728.12 KSA02791.1 - 0.02 14.8 0.0 0.32 10.9 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) Chlorophyllase2 PF12740.7 KSA02791.1 - 0.038 12.9 0.0 0.064 12.2 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme PGAP1 PF07819.13 KSA02791.1 - 0.062 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein DUF676 PF05057.14 KSA02791.1 - 0.07 12.6 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Lipase_3 PF01764.25 KSA02791.1 - 0.074 12.9 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_1 PF00561.20 KSA02791.1 - 0.076 12.6 2.8 0.12 12.0 1.0 2.1 1 1 1 2 2 2 0 alpha/beta hydrolase fold DUF915 PF06028.11 KSA02791.1 - 0.098 12.0 0.2 0.36 10.1 0.1 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_6 PF12697.7 KSA02791.1 - 0.099 13.2 0.0 0.12 13.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family MFS_1 PF07690.16 KSA02792.1 - 7.2e-22 77.8 32.5 2.5e-15 56.2 12.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KSA02792.1 - 5.7e-19 68.3 20.6 6.6e-18 64.8 20.6 2.8 1 1 0 1 1 1 1 Sugar (and other) transporter DUF3361 PF11841.8 KSA02793.1 - 0.055 13.4 0.0 0.074 13.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3361) PLA2_B PF01735.18 KSA02794.1 - 3.7e-202 672.1 5.7 4.4e-202 671.8 5.7 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain IBR PF01485.21 KSA02794.1 - 0.018 15.3 1.7 0.035 14.3 1.7 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Response_reg PF00072.24 KSA02795.1 - 9.2e-29 99.9 0.1 1.9e-28 98.8 0.1 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 KSA02795.1 - 9.7e-27 93.7 0.5 7.1e-20 71.6 0.0 3.0 3 0 0 3 3 3 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KSA02795.1 - 3.6e-13 49.3 0.6 9.4e-13 48.0 0.6 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 KSA02795.1 - 0.00055 20.3 0.1 0.26 11.7 0.1 2.6 2 0 0 2 2 2 2 HAMP domain DNA_pol_A_exoN PF18305.1 KSA02795.1 - 0.2 11.9 0.0 2.4 8.5 0.0 2.4 2 0 0 2 2 2 0 3' to 5' exonuclease C-terminal domain DPPIV_N PF00930.21 KSA02796.1 - 5.4e-99 331.3 10.2 7.4e-99 330.9 10.2 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 KSA02796.1 - 1.1e-45 155.7 0.4 1.9e-45 154.9 0.4 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 KSA02796.1 - 0.03 14.9 0.0 0.095 13.3 0.0 1.6 1 1 1 2 2 2 0 Alpha/beta hydrolase family TCTP PF00838.17 KSA02797.1 - 1.9e-72 243.0 0.9 2.1e-72 242.8 0.9 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein Tim44 PF04280.15 KSA02797.1 - 0.0069 16.5 0.3 0.16 12.1 0.2 2.2 1 1 1 2 2 2 2 Tim44-like domain DUF2937 PF11157.8 KSA02797.1 - 0.2 11.4 0.0 0.31 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) TRM13 PF05206.14 KSA02798.1 - 5.4e-84 281.8 0.6 1.2e-83 280.6 0.6 1.6 1 0 0 1 1 1 1 Methyltransferase TRM13 zf-TRM13_CCCH PF11722.8 KSA02798.1 - 3.6e-13 49.0 6.8 1e-12 47.6 6.8 1.8 1 0 0 1 1 1 1 CCCH zinc finger in TRM13 protein zf-U11-48K PF05253.12 KSA02798.1 - 1.9e-09 37.2 1.0 4e-09 36.2 1.0 1.6 1 0 0 1 1 1 1 U11-48K-like CHHC zinc finger DUF896 PF05979.12 KSA02798.1 - 1.5 8.7 6.2 4.7 7.2 0.6 3.3 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF896) BUD22 PF09073.10 KSA02799.1 - 9.3e-80 269.1 32.0 9.3e-80 269.1 32.0 1.4 1 1 1 2 2 2 1 BUD22 Enkurin PF13864.6 KSA02799.1 - 2.2 8.8 13.4 4.1 7.9 0.7 3.0 2 0 0 2 2 2 0 Calmodulin-binding PRKCSH-like PF12999.7 KSA02800.1 - 1e-60 204.5 4.6 1e-60 204.5 4.6 1.9 2 0 0 2 2 2 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 KSA02800.1 - 5e-50 169.2 0.4 5e-50 169.2 0.4 2.3 2 1 0 2 2 2 1 Glucosidase II beta subunit-like protein DUF2813 PF11398.8 KSA02800.1 - 0.0062 15.8 5.8 0.0087 15.4 5.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2813) E2R135 PF11570.8 KSA02800.1 - 0.071 13.4 9.6 1 9.6 0.1 2.8 3 0 0 3 3 3 0 Coiled-coil receptor-binding R-domain of colicin E2 DUF745 PF05335.13 KSA02800.1 - 0.16 11.7 1.6 0.27 10.9 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF745) DivIC PF04977.15 KSA02800.1 - 1.1 9.1 6.5 0.54 10.1 0.1 3.1 3 0 0 3 3 3 0 Septum formation initiator adh_short PF00106.25 KSA02802.1 - 5.8e-32 110.7 0.0 1e-31 109.9 0.0 1.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KSA02802.1 - 6.2e-22 78.3 0.0 1.6e-21 77.0 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KSA02802.1 - 0.0059 16.5 0.0 0.0098 15.8 0.0 1.4 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 KSA02802.1 - 0.045 13.1 0.1 0.12 11.7 0.0 1.8 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain TaqI_C PF12950.7 KSA02802.1 - 0.073 13.1 0.1 0.11 12.6 0.1 1.3 1 0 0 1 1 1 0 TaqI-like C-terminal specificity domain Peptidase_S24 PF00717.23 KSA02803.1 - 4.5e-08 32.9 0.0 6.5e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like Flavoprotein PF02441.19 KSA02804.1 - 1.4e-47 161.3 0.4 2.5e-47 160.5 0.4 1.4 1 0 0 1 1 1 1 Flavoprotein Toxin-JAB1 PF15659.6 KSA02804.1 - 0.00026 21.3 2.3 0.021 15.2 0.0 3.2 3 0 0 3 3 3 1 JAB-like toxin 1 Nop14 PF04147.12 KSA02804.1 - 1.3 7.1 30.5 2.2 6.4 30.5 1.3 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 KSA02804.1 - 3.9 5.6 24.9 6.1 5.0 24.9 1.2 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 KSA02804.1 - 8.8 5.6 37.4 14 5.0 37.4 1.2 1 0 0 1 1 1 0 SDA1 DJ-1_PfpI PF01965.24 KSA02805.1 - 1.2e-06 28.4 0.0 6.1e-06 26.1 0.0 1.9 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 KSA02805.1 - 0.0014 18.4 0.5 0.0033 17.1 0.5 1.7 1 1 0 1 1 1 1 ThiJ/PfpI family-like DUF3198 PF11433.8 KSA02805.1 - 0.37 10.7 1.6 19 5.2 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3198) Ydc2-catalyt PF09159.10 KSA02806.1 - 8.3e-50 170.1 0.4 1.7e-49 169.1 0.4 1.5 1 1 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Pox_F15 PF04596.12 KSA02806.1 - 0.033 14.0 0.1 0.093 12.5 0.1 1.7 1 0 0 1 1 1 0 Poxvirus protein F15 Pox_A22 PF04848.13 KSA02806.1 - 0.034 14.3 1.2 1.3 9.2 0.3 3.2 2 1 0 2 2 2 0 Poxvirus A22 protein SSP160 PF06933.11 KSA02807.1 - 0.14 10.4 12.0 0.13 10.4 12.0 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 TRM PF02005.16 KSA02808.1 - 2.1e-132 441.8 0.0 2.7e-132 441.5 0.0 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.16 KSA02808.1 - 1.2e-06 28.4 0.0 2.5e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein DUF2067 PF09840.9 KSA02808.1 - 0.0011 18.6 0.0 0.0042 16.7 0.0 1.9 2 0 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2067) DUF655 PF04919.12 KSA02808.1 - 0.004 17.1 0.0 0.0094 15.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF655) CpXC PF14353.6 KSA02808.1 - 0.078 13.0 0.2 2.2 8.4 0.2 2.6 1 1 0 1 1 1 0 CpXC protein IFRD PF05004.13 KSA02809.1 - 0.3 10.2 0.8 0.37 9.8 0.8 1.0 1 0 0 1 1 1 0 Interferon-related developmental regulator (IFRD) DHHC PF01529.20 KSA02811.1 - 3.7e-32 111.2 17.7 5.9e-32 110.6 17.7 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase ATP_bind_3 PF01171.20 KSA02811.1 - 0.057 13.2 0.0 0.099 12.4 0.0 1.3 1 0 0 1 1 1 0 PP-loop family Collagen PF01391.18 KSA02812.1 - 4.8e-07 29.4 19.0 6.9e-07 28.9 19.0 1.1 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Cyc-maltodext_N PF09087.11 KSA02812.1 - 0.02 15.2 3.5 0.02 15.2 3.5 3.3 1 1 1 3 3 3 0 Cyclomaltodextrinase, N-terminal Fungal_trans PF04082.18 KSA02815.1 - 1.9e-25 89.4 4.5 1.9e-25 89.4 4.5 2.8 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KSA02815.1 - 5.2e-06 26.5 9.8 1.1e-05 25.4 9.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ARPC4 PF05856.12 KSA02816.1 - 8.3e-56 188.2 5.6 9.1e-56 188.0 5.6 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) FF PF01846.19 KSA02817.1 - 3.6e-24 84.7 17.0 4.6e-12 45.9 0.3 5.8 6 0 0 6 6 6 4 FF domain WW PF00397.26 KSA02817.1 - 4.9e-18 64.9 17.6 6.2e-09 35.8 5.3 2.5 2 0 0 2 2 2 2 WW domain Glyco_hyd_101C PF17451.2 KSA02817.1 - 0.0075 16.6 8.6 0.058 13.7 0.8 3.3 2 1 1 3 3 3 2 Glycosyl hydrolase 101 beta sandwich domain DUF4709 PF15821.5 KSA02817.1 - 2 8.7 7.6 1.6 9.1 0.6 3.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4709) RhoGAP-FF1 PF16512.5 KSA02817.1 - 2.7 8.8 9.1 9.6 7.0 0.6 4.5 4 1 0 4 4 4 0 p190-A and -B Rho GAPs FF domain Sortilin-Vps10 PF15902.5 KSA02819.1 - 3.2e-244 810.6 32.6 2.8e-142 474.6 6.9 2.7 3 0 0 3 3 3 2 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 KSA02819.1 - 6.2e-71 238.2 35.2 1.9e-44 152.0 7.9 2.7 3 0 0 3 3 3 2 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 KSA02819.1 - 3.5e-10 38.3 46.6 0.11 12.6 0.1 11.7 12 0 0 12 12 12 7 BNR/Asp-box repeat PSII_BNR PF14870.6 KSA02819.1 - 0.00034 20.0 0.3 0.3 10.3 0.0 4.1 4 0 0 4 4 4 1 Photosynthesis system II assembly factor YCF48 BNR_2 PF13088.6 KSA02819.1 - 0.0014 18.0 2.7 13 4.9 0.0 6.2 5 3 0 6 6 6 1 BNR repeat-like domain CHB_HEX_C PF03174.13 KSA02819.1 - 0.004 17.1 0.4 3.2 7.8 0.0 4.8 5 0 0 5 5 5 1 Chitobiase/beta-hexosaminidase C-terminal domain DsbG_N PF18257.1 KSA02819.1 - 0.21 11.8 2.7 0.53 10.5 1.0 2.5 2 0 0 2 2 2 0 Disulfide isomerase DsbG N-terminal Rax2 PF12768.7 KSA02820.1 - 7.5e-57 192.2 0.7 7.5e-57 192.2 0.7 5.5 3 1 3 6 6 6 1 Cortical protein marker for cell polarity TRAPPC-Trs85 PF12739.7 KSA02821.1 - 4.9e-103 345.2 4.9 6.3e-103 344.9 4.9 1.1 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit CLAMP PF14769.6 KSA02821.1 - 0.14 12.6 2.2 33 5.0 0.1 3.7 3 0 0 3 3 3 0 Flagellar C1a complex subunit C1a-32 Ycf15 PF10705.9 KSA02821.1 - 2.1 8.5 5.3 25 5.1 0.2 3.0 2 0 0 2 2 2 0 Chloroplast protein precursor Ycf15 putative Folate_carrier PF01770.18 KSA02821.1 - 2.9 6.5 7.8 0.3 9.8 0.9 2.1 2 0 0 2 2 2 0 Reduced folate carrier DUF1751 PF08551.10 KSA02822.1 - 4.5e-26 91.3 3.0 4.5e-26 91.3 3.0 2.5 3 0 0 3 3 3 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 KSA02822.1 - 0.00022 21.2 8.2 0.00049 20.1 8.2 1.5 1 0 0 1 1 1 1 Rhomboid family DUF5321 PF17254.2 KSA02823.1 - 5.2e-10 39.0 3.3 6.5e-10 38.7 3.3 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5321) MCM PF00493.23 KSA02824.1 - 2.8e-102 340.5 0.1 5.5e-102 339.6 0.0 1.5 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 KSA02824.1 - 1.5e-38 131.4 0.9 3.6e-38 130.3 0.9 1.6 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KSA02824.1 - 3.7e-28 97.8 2.4 3.7e-28 97.8 2.4 2.2 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 KSA02824.1 - 4e-19 69.1 1.2 2.1e-18 66.8 1.2 2.4 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KSA02824.1 - 3.9e-06 26.4 0.0 0.00015 21.2 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KSA02824.1 - 6.8e-06 26.1 0.0 2.5e-05 24.3 0.0 2.1 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KSA02824.1 - 0.00014 21.7 0.0 0.0041 17.0 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KSA02824.1 - 0.051 13.3 0.3 2.8 7.6 0.0 3.1 3 0 0 3 3 3 0 Sigma-54 interaction domain Rad51 PF08423.11 KSA02825.1 - 2.9e-99 331.5 0.0 3.2e-99 331.3 0.0 1.0 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 KSA02825.1 - 1.3e-05 24.9 0.0 1.7e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KSA02825.1 - 0.029 14.7 0.0 0.051 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Snapin_Pallidin PF14712.6 KSA02826.1 - 0.0092 16.4 2.3 0.023 15.1 2.3 1.6 1 0 0 1 1 1 1 Snapin/Pallidin PAXNEB PF05625.11 KSA02827.1 - 1.3e-98 330.6 0.7 1.5e-98 330.3 0.7 1.0 1 0 0 1 1 1 1 PAXNEB protein Serinc PF03348.15 KSA02828.1 - 1.4e-143 478.9 13.9 1.6e-143 478.7 13.9 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) SPW PF03779.14 KSA02828.1 - 2.9 7.5 11.3 23 4.7 0.0 4.4 4 0 0 4 4 4 0 SPW repeat DUF1077 PF06417.12 KSA02828.1 - 9.1 6.3 13.1 0.48 10.4 5.1 2.9 4 0 0 4 4 4 0 Protein of unknown function (DUF1077) ATP-synt_G PF04718.15 KSA02829.1 - 2.4e-30 105.3 1.0 2.8e-30 105.1 1.0 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase g subunit DEAD PF00270.29 KSA02830.1 - 5.5e-42 143.5 2.1 1.3e-41 142.3 0.3 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KSA02830.1 - 6.6e-30 103.7 7.5 1.6e-29 102.5 0.1 3.0 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 KSA02830.1 - 2.1e-07 31.1 0.0 2.1e-07 31.1 0.0 2.7 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Terminase_6 PF03237.15 KSA02830.1 - 0.71 9.5 3.4 3.4 7.3 0.0 3.0 3 0 0 3 3 3 0 Terminase-like family Ribonucleas_3_3 PF14622.6 KSA02831.1 - 2.4e-28 98.8 0.1 4.5e-28 98.0 0.1 1.4 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 KSA02831.1 - 0.016 15.9 0.1 0.062 13.9 0.1 2.0 1 1 1 2 2 2 0 Ribonuclease III domain GIT_SHD PF08518.11 KSA02832.1 - 2.7e-24 84.4 6.7 8.2e-13 47.7 1.4 2.9 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT GIT1_C PF12205.8 KSA02832.1 - 5.6e-07 29.7 1.8 2.8e-06 27.4 1.8 2.3 1 0 0 1 1 1 1 G protein-coupled receptor kinase-interacting protein 1 C term SPAM PF02090.15 KSA02832.1 - 0.38 10.6 6.9 82 3.0 6.9 2.7 1 1 0 1 1 1 0 Salmonella surface presentation of antigen gene type M protein HALZ PF02183.18 KSA02832.1 - 1.8 8.8 14.2 2.2 8.5 4.9 3.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF573 PF04504.14 KSA02832.1 - 2.5 8.8 8.0 0.55 10.9 1.5 3.5 3 0 0 3 3 3 0 Protein of unknown function, DUF573 Cwf_Cwc_15 PF04889.12 KSA02833.1 - 5.1e-42 144.3 28.9 8e-41 140.4 28.9 2.0 1 1 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Pet100 PF09803.9 KSA02833.1 - 0.44 11.1 4.0 27 5.4 2.6 2.5 2 0 0 2 2 2 0 Pet100 PA26 PF04636.13 KSA02833.1 - 1.8 7.4 10.5 2.3 7.0 10.5 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Fungal_trans PF04082.18 KSA02834.1 - 1.3e-12 47.3 1.2 6.3e-12 45.1 1.2 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain TPR_8 PF13181.6 KSA02835.1 - 2e-05 24.5 3.6 0.035 14.3 0.0 4.7 6 0 0 6 6 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KSA02835.1 - 0.00016 21.8 2.3 0.014 15.6 0.0 3.1 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 KSA02835.1 - 0.002 17.6 0.1 1.1 8.6 0.0 2.5 2 0 0 2 2 2 2 MalT-like TPR region TPR_2 PF07719.17 KSA02835.1 - 0.0035 17.3 1.0 4.6 7.6 0.0 3.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 KSA02835.1 - 0.019 15.4 8.2 0.23 12.0 0.9 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 KSA02835.1 - 0.073 12.8 0.8 0.81 9.4 0.0 3.1 3 0 0 3 3 3 0 TPR repeat PglD_N PF17836.1 KSA02835.1 - 0.08 13.6 0.2 0.4 11.3 0.1 2.3 2 0 0 2 2 2 0 PglD N-terminal domain Cytochrom_C_2 PF01322.20 KSA02835.1 - 0.87 10.5 3.5 8.5 7.3 2.1 2.7 1 1 1 2 2 2 0 Cytochrome C' Sec8_exocyst PF04048.14 KSA02835.1 - 2.5 8.0 9.7 0.28 11.1 1.3 2.7 2 1 0 2 2 2 0 Sec8 exocyst complex component specific domain SYF2 PF08231.12 KSA02836.1 - 0.005 17.3 4.3 0.0074 16.7 4.3 1.3 1 0 0 1 1 1 1 SYF2 splicing factor DUF3545 PF12065.8 KSA02836.1 - 0.02 14.9 4.8 1.3 9.1 0.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3545) Ad_cyc_g-alpha PF08509.11 KSA02836.1 - 0.12 12.2 0.2 0.22 11.2 0.2 1.4 1 0 0 1 1 1 0 Adenylate cyclase G-alpha binding domain DUF4477 PF14780.6 KSA02836.1 - 2.4 7.7 6.0 3 7.4 0.4 2.8 2 1 0 3 3 3 0 Domain of unknown function (DUF4477) zf-C2H2_4 PF13894.6 KSA02837.1 - 0.0037 18.0 16.2 0.0068 17.1 2.0 4.6 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2 PF00096.26 KSA02837.1 - 0.015 15.7 3.5 0.015 15.7 3.5 4.2 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KSA02837.1 - 0.54 10.8 13.7 1.7 9.2 0.9 4.1 4 0 0 4 4 4 0 Zinc-finger double domain OrfB_Zn_ribbon PF07282.11 KSA02837.1 - 3 7.8 8.4 7.1 6.6 0.8 3.1 2 1 1 3 3 3 0 Putative transposase DNA-binding domain C1_2 PF03107.16 KSA02837.1 - 7.2 7.0 8.3 19 5.7 0.2 3.0 3 0 0 3 3 3 0 C1 domain Spermine_synth PF01564.17 KSA02838.1 - 1.9e-56 190.5 0.3 3.1e-56 189.8 0.3 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 KSA02838.1 - 4.5e-22 77.7 0.1 8e-22 76.9 0.1 1.4 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Tetrabrachion PF11401.8 KSA02838.1 - 0.012 15.6 0.1 0.029 14.4 0.1 1.6 1 0 0 1 1 1 0 Tetrabrachion DUF43 PF01861.16 KSA02838.1 - 0.033 13.4 0.1 0.06 12.6 0.1 1.3 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain NAD_binding_7 PF13241.6 KSA02838.1 - 0.15 12.5 0.1 0.31 11.5 0.1 1.9 1 1 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox_2 PF07992.14 KSA02838.1 - 0.22 10.7 0.0 0.3 10.3 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AFT PF08731.11 KSA02839.1 - 3.5e-07 30.6 0.1 3.5e-07 30.6 0.1 3.3 3 1 0 3 3 3 1 Transcription factor AFT FAR1 PF03101.15 KSA02839.1 - 0.0032 18.1 1.3 0.0032 18.1 1.3 2.9 3 1 0 3 3 3 1 FAR1 DNA-binding domain ArgJ PF01960.18 KSA02839.1 - 0.024 13.4 1.4 0.058 12.1 1.0 1.7 2 0 0 2 2 2 0 ArgJ family TFIIA PF03153.13 KSA02839.1 - 0.057 13.4 28.0 0.66 9.9 8.8 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Ribosomal_S13_N PF08069.12 KSA02839.1 - 0.12 12.5 0.0 0.4 10.7 0.0 2.0 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain CRAL_TRIO_2 PF13716.6 KSA02840.1 - 1e-14 54.8 3.6 3.3e-14 53.2 3.6 1.9 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain RhoGAP PF00620.27 KSA02840.1 - 6.8e-08 32.5 1.6 1.6e-07 31.3 0.5 2.2 2 0 0 2 2 2 1 RhoGAP domain RPN1_RPN2_N PF17781.1 KSA02841.1 - 1.6e-111 372.6 2.1 3.2e-111 371.6 2.1 1.5 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 KSA02841.1 - 6.2e-27 93.4 0.1 1.1e-26 92.5 0.1 1.5 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 KSA02841.1 - 1.1e-26 91.9 15.0 3e-05 24.2 0.6 9.7 10 0 0 10 10 10 4 Proteasome/cyclosome repeat HEAT_2 PF13646.6 KSA02841.1 - 9e-08 32.4 0.1 0.033 14.6 0.0 3.9 3 1 1 4 4 4 2 HEAT repeats Zip PF02535.22 KSA02841.1 - 0.015 14.5 0.1 0.015 14.5 0.1 2.0 2 0 0 2 2 2 0 ZIP Zinc transporter Utp13 PF08625.11 KSA02841.1 - 0.12 12.2 0.1 0.52 10.2 0.1 2.1 1 0 0 1 1 1 0 Utp13 specific WD40 associated domain Raftlin PF15250.6 KSA02841.1 - 6.3 5.4 7.8 0.23 10.2 1.6 1.7 2 0 0 2 2 2 0 Raftlin NOA36 PF06524.12 KSA02841.1 - 9.5 5.4 15.1 17 4.6 15.1 1.3 1 0 0 1 1 1 0 NOA36 protein ATP-synt_C PF00137.21 KSA02842.1 - 1.1e-26 93.0 30.1 2.8e-15 56.4 12.6 2.2 2 0 0 2 2 2 2 ATP synthase subunit C SLATT_5 PF18160.1 KSA02842.1 - 0.35 10.2 2.3 0.67 9.3 0.2 2.0 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 HAD_2 PF13419.6 KSA02843.1 - 1.1e-15 58.2 0.0 1.8e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KSA02843.1 - 1.5e-11 45.0 0.0 2.9e-07 31.0 0.0 2.2 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 KSA02843.1 - 0.00012 22.6 0.0 0.00017 22.1 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KSA02843.1 - 0.00068 19.7 0.0 0.0013 18.8 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 KSA02843.1 - 0.013 15.6 0.0 0.21 11.7 0.0 2.4 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase BTB_2 PF02214.22 KSA02844.1 - 2.8e-09 37.2 1.3 0.00026 21.3 0.3 2.5 2 0 0 2 2 2 2 BTB/POZ domain Fungal_trans_2 PF11951.8 KSA02845.1 - 7.6e-27 94.1 6.2 1.3e-26 93.3 6.2 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KSA02845.1 - 1.4e-11 44.3 7.1 2.2e-11 43.7 7.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 KSA02846.1 - 2.6e-09 37.0 9.3 4.1e-09 36.4 9.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EMP70 PF02990.16 KSA02847.1 - 1.4e-197 657.5 20.5 1.9e-197 657.1 20.5 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 PIRT PF15099.6 KSA02847.1 - 4.2 7.0 9.0 1.1 8.9 2.4 2.7 2 1 0 2 2 2 0 Phosphoinositide-interacting protein family APG6 PF04111.12 KSA02849.1 - 2.5e-56 190.5 0.2 2.5e-56 190.5 0.2 2.1 2 1 1 3 3 3 1 Apg6 BARA domain APG6_N PF17675.1 KSA02849.1 - 8.4e-21 74.9 21.4 8.4e-21 74.9 21.4 1.7 2 0 0 2 2 2 1 Apg6 coiled-coil region Exonuc_VII_L PF02601.15 KSA02849.1 - 0.53 9.8 7.2 0.76 9.3 7.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Ribosomal_L18 PF17135.4 KSA02850.1 - 3.6e-85 284.1 3.1 4e-85 283.9 3.1 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 KSA02850.1 - 0.014 16.1 0.9 0.052 14.2 0.9 2.0 1 1 0 1 1 1 0 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Nudc_N PF14050.6 KSA02850.1 - 0.11 12.5 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 N-terminal conserved domain of Nudc. CMV_US PF08001.11 KSA02851.1 - 0.072 12.4 0.3 0.11 11.7 0.3 1.2 1 0 0 1 1 1 0 CMV US Prefoldin PF02996.17 KSA02852.1 - 1.3e-28 99.3 5.0 2e-28 98.7 5.0 1.3 1 0 0 1 1 1 1 Prefoldin subunit KxDL PF10241.9 KSA02852.1 - 0.013 15.8 1.2 0.36 11.1 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein Tsi6 PF18660.1 KSA02852.1 - 0.039 14.0 1.8 0.07 13.2 0.2 2.2 2 1 0 2 2 2 0 Tsi6 DUF1664 PF07889.12 KSA02852.1 - 0.081 13.0 2.2 4.7 7.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) YebG PF07130.12 KSA02852.1 - 0.1 12.5 1.5 0.12 12.2 0.2 1.8 2 0 0 2 2 2 0 YebG protein Prefoldin_2 PF01920.20 KSA02852.1 - 0.28 11.2 8.5 0.16 11.9 1.1 2.3 1 1 1 2 2 2 0 Prefoldin subunit SlyX PF04102.12 KSA02852.1 - 0.43 11.2 0.2 0.43 11.2 0.2 2.4 3 1 0 3 3 3 0 SlyX Glyco_hydro_18 PF00704.28 KSA02853.1 - 3.4e-40 138.7 6.3 4.4e-40 138.3 6.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 KSA02853.1 - 1.1e-10 41.8 12.1 3.3e-10 40.2 12.1 1.9 1 0 0 1 1 1 1 Chitin recognition protein LysM PF01476.20 KSA02853.1 - 4.2e-05 23.5 0.0 0.00017 21.6 0.0 2.2 2 0 0 2 2 2 1 LysM domain Thi4 PF01946.17 KSA02854.1 - 2.4e-107 357.5 0.0 3e-107 357.2 0.0 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 KSA02854.1 - 2.1e-07 30.8 1.4 4.8e-07 29.7 1.0 1.6 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KSA02854.1 - 1e-06 28.2 0.0 1.6e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KSA02854.1 - 1e-06 28.8 0.1 2.7e-06 27.5 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KSA02854.1 - 7e-06 25.3 0.9 1.4e-05 24.4 0.4 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KSA02854.1 - 1.8e-05 24.0 2.3 0.00013 21.2 1.2 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 KSA02854.1 - 0.00052 20.0 1.1 0.0017 18.4 0.1 2.2 2 1 1 3 3 3 1 FAD-NAD(P)-binding HI0933_like PF03486.14 KSA02854.1 - 0.0027 16.5 0.6 0.0038 16.0 0.6 1.2 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 KSA02854.1 - 0.0076 15.4 0.5 0.014 14.5 0.5 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 KSA02854.1 - 0.0091 15.4 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KSA02854.1 - 0.01 15.1 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 KSA02854.1 - 0.014 14.7 0.0 0.021 14.1 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KSA02854.1 - 0.058 12.2 0.5 0.089 11.6 0.5 1.2 1 0 0 1 1 1 0 Tryptophan halogenase UPF0020 PF01170.18 KSA02855.1 - 1.5e-08 34.6 0.0 5.4e-07 29.5 0.0 2.3 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.18 KSA02855.1 - 0.00064 19.5 0.1 0.17 11.6 0.0 2.6 2 0 0 2 2 2 2 DNA methylase N6_Mtase PF02384.16 KSA02855.1 - 0.01 15.1 0.0 0.035 13.4 0.0 1.8 1 1 0 1 1 1 0 N-6 DNA Methylase RRM_1 PF00076.22 KSA02856.1 - 9.9e-33 111.8 0.2 3.7e-15 55.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KSA02856.1 - 2.8e-12 46.6 0.4 6e-07 29.5 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 KSA02856.1 - 0.0033 17.4 0.1 1.7 8.7 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.13 KSA02856.1 - 0.13 12.2 0.1 2.8 8.0 0.1 2.3 1 1 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Presenilin PF01080.17 KSA02856.1 - 6.5 5.4 7.5 9.3 4.9 7.5 1.2 1 0 0 1 1 1 0 Presenilin DEAD PF00270.29 KSA02857.1 - 1.4e-50 171.4 0.0 5.3e-49 166.4 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KSA02857.1 - 7.3e-23 81.0 1.4 5.3e-22 78.3 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 KSA02857.1 - 1e-16 60.9 4.0 1e-16 60.9 4.0 2.7 2 0 0 2 2 2 1 DBP10CT (NUC160) domain ERCC3_RAD25_C PF16203.5 KSA02857.1 - 0.008 15.4 0.0 0.032 13.4 0.0 2.0 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase Clat_adaptor_s PF01217.20 KSA02858.1 - 2e-52 176.9 2.5 2.3e-52 176.7 2.5 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Mannosyl_trans3 PF11051.8 KSA02859.1 - 1.2e-81 274.1 0.0 2.1e-81 273.3 0.0 1.4 1 0 0 1 1 1 1 Mannosyltransferase putative TctB PF07331.11 KSA02859.1 - 0.15 12.4 0.9 0.33 11.2 0.9 1.5 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family Glyco_transf_15 PF01793.16 KSA02860.1 - 1.7e-41 142.6 6.0 1.9e-41 142.4 6.0 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DUF5106 PF17127.4 KSA02860.1 - 0.028 14.7 0.2 0.035 14.4 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) IPK PF03770.16 KSA02862.1 - 2.7e-52 177.5 0.0 7.8e-52 176.0 0.0 1.9 1 0 0 1 1 1 1 Inositol polyphosphate kinase DUF3446 PF11928.8 KSA02863.1 - 0.25 11.7 7.7 0.068 13.5 5.2 1.4 2 0 0 2 2 2 0 Early growth response N-terminal domain SR-25 PF10500.9 KSA02863.1 - 4.2 6.9 10.8 5 6.7 10.8 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DASH_Dad1 PF08649.10 KSA02864.1 - 1.5e-24 85.9 0.1 2.1e-24 85.4 0.1 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad1 Presenilin PF01080.17 KSA02864.1 - 0.29 9.9 1.3 0.24 10.1 1.3 1.1 1 0 0 1 1 1 0 Presenilin NOA36 PF06524.12 KSA02864.1 - 0.36 10.1 6.4 0.36 10.1 6.4 1.1 1 0 0 1 1 1 0 NOA36 protein ORC_WH_C PF18137.1 KSA02864.1 - 1.7 8.7 7.7 2.2 8.4 7.7 1.1 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal ADH_N PF08240.12 KSA02865.1 - 9e-28 96.3 3.9 1.7e-27 95.5 3.4 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KSA02865.1 - 2.7e-19 69.4 0.0 5.2e-19 68.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KSA02865.1 - 5.7e-08 32.5 0.0 9.2e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_N_assoc PF13823.6 KSA02865.1 - 0.011 15.6 0.0 0.023 14.6 0.0 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated ADH_N PF08240.12 KSA02866.1 - 1.6e-28 98.8 2.7 3.1e-28 97.8 2.7 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KSA02866.1 - 1.9e-16 60.2 0.0 3.1e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KSA02866.1 - 7.6e-05 22.3 0.0 0.00011 21.7 0.0 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus eIF-1a PF01176.19 KSA02866.1 - 0.045 13.6 0.0 0.096 12.5 0.0 1.5 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 ADH_N_assoc PF13823.6 KSA02866.1 - 0.062 13.2 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated FMN_red PF03358.15 KSA02868.1 - 8.4e-09 35.3 0.0 2e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.25 KSA02868.1 - 0.0002 21.6 4.1 0.00033 20.9 0.3 2.6 2 1 0 2 2 2 1 Flavodoxin Flavodoxin_5 PF12724.7 KSA02868.1 - 0.00029 21.1 0.0 0.24 11.6 0.2 2.4 2 0 0 2 2 2 2 Flavodoxin domain FMN_red PF03358.15 KSA02869.1 - 2.7e-10 40.2 0.0 3.6e-10 39.8 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 KSA02869.1 - 1.5e-06 28.1 0.0 1.9e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 KSA02869.1 - 0.0072 16.5 0.2 0.13 12.5 0.2 2.4 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.7 KSA02869.1 - 0.091 13.0 0.0 0.1 12.9 0.0 1.3 1 0 0 1 1 1 0 Flavodoxin domain zf-C2H2_4 PF13894.6 KSA02870.1 - 0.12 13.3 2.8 0.19 12.7 2.8 1.3 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KSA02870.1 - 0.16 12.5 2.1 0.24 11.9 2.1 1.3 1 0 0 1 1 1 0 Zinc finger, C2H2 type PNP_phzG_C PF10590.9 KSA02871.1 - 6.6e-19 67.7 0.7 1.3e-18 66.8 0.7 1.5 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Putative_PNPOx PF01243.20 KSA02871.1 - 1.3e-12 47.7 0.0 2e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.7 KSA02871.1 - 0.0048 17.5 0.2 0.0094 16.5 0.2 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase GEP5 PF17053.5 KSA02871.1 - 0.11 12.3 0.1 0.15 11.9 0.1 1.2 1 0 0 1 1 1 0 Genetic interactor of prohibitin 5 Cupin_8 PF13621.6 KSA02872.1 - 3.2e-13 50.0 2.0 5.5e-12 45.9 0.0 2.8 1 1 2 3 3 3 1 Cupin-like domain JmjC PF02373.22 KSA02872.1 - 3.8e-09 37.0 0.5 0.0002 21.8 0.1 2.9 2 0 0 2 2 2 2 JmjC domain, hydroxylase Elongin_A PF06881.11 KSA02872.1 - 0.0056 17.2 2.3 0.16 12.5 0.1 3.1 3 0 0 3 3 3 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Cupin_2 PF07883.11 KSA02872.1 - 0.14 11.9 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 Cupin domain Ribosomal_L32p PF01783.23 KSA02873.1 - 8.9e-14 51.5 2.0 1.9e-13 50.4 2.0 1.6 1 0 0 1 1 1 1 Ribosomal L32p protein family MtrG PF04210.13 KSA02873.1 - 0.04 13.8 0.1 2 8.3 0.0 2.3 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G zf-ribbon_3 PF13248.6 KSA02873.1 - 0.084 12.3 2.2 0.16 11.4 2.2 1.4 1 0 0 1 1 1 0 zinc-ribbon domain Rubredoxin_2 PF18073.1 KSA02873.1 - 0.39 10.5 0.2 0.39 10.5 0.2 1.7 2 0 0 2 2 2 0 Rubredoxin metal binding domain Septin PF00735.18 KSA02874.1 - 2.1e-111 371.7 3.2 2.7e-111 371.4 3.2 1.1 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KSA02874.1 - 7.8e-10 38.8 0.1 1.4e-09 38.0 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KSA02874.1 - 3e-07 30.5 0.7 1.2e-06 28.6 0.1 2.0 2 0 0 2 2 2 1 RsgA GTPase AIG1 PF04548.16 KSA02874.1 - 4.6e-06 26.1 1.1 1.7e-05 24.2 1.1 2.0 1 1 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.27 KSA02874.1 - 0.0004 20.0 0.2 0.014 15.0 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Roc PF08477.13 KSA02874.1 - 0.0017 18.5 0.1 0.0051 17.0 0.0 1.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase NB-ARC PF00931.22 KSA02874.1 - 0.0038 16.4 0.0 0.0071 15.5 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain Dynamin_N PF00350.23 KSA02874.1 - 0.0041 17.2 1.6 1.3 9.1 0.1 2.6 1 1 1 2 2 2 2 Dynamin family AAA_22 PF13401.6 KSA02874.1 - 0.029 14.7 0.5 0.3 11.3 0.1 2.2 1 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KSA02874.1 - 0.048 14.2 3.0 0.039 14.5 1.4 1.9 1 1 1 2 2 2 0 ABC transporter FtsK_SpoIIIE PF01580.18 KSA02874.1 - 0.072 12.4 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_16 PF13191.6 KSA02874.1 - 0.097 13.0 0.1 0.18 12.2 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain FeoB_N PF02421.18 KSA02874.1 - 1 8.9 3.6 5.1 6.6 1.6 2.5 2 1 0 2 2 2 0 Ferrous iron transport protein B Glyco_transf_8 PF01501.20 KSA02875.1 - 3.2e-22 79.3 0.2 7.4e-22 78.1 0.2 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 8 Nucleotid_trans PF03407.16 KSA02875.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase Thiamine_BP PF01910.17 KSA02876.1 - 3.1e-19 68.7 0.1 3.5e-19 68.5 0.1 1.0 1 0 0 1 1 1 1 Thiamine-binding protein Myb_DNA-binding PF00249.31 KSA02877.1 - 0.00066 19.8 0.5 0.31 11.3 0.2 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KSA02877.1 - 0.089 13.1 1.9 0.26 11.6 0.2 2.4 2 1 1 3 3 3 0 Myb-like DNA-binding domain CCDC24 PF15669.5 KSA02877.1 - 0.22 11.3 2.5 1.3 8.8 2.5 2.0 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 24 family ThiF PF00899.21 KSA02878.1 - 1.2e-105 352.3 0.0 7.4e-76 254.7 0.0 2.2 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 KSA02878.1 - 8e-91 304.4 1.0 1.4e-90 303.6 1.0 1.4 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_UFD PF09358.10 KSA02878.1 - 3.3e-37 127.1 0.3 9.4e-37 125.6 0.1 2.0 2 0 0 2 2 2 1 Ubiquitin fold domain E1_FCCH PF16190.5 KSA02878.1 - 8e-28 96.5 0.3 1.8e-27 95.3 0.3 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 KSA02878.1 - 3.7e-25 87.9 1.5 9.8e-25 86.6 0.4 2.4 3 0 0 3 3 3 1 Ubiquitin-activating enzyme E1 four-helix bundle ABC_membrane PF00664.23 KSA02879.1 - 5.3e-86 288.7 41.5 1.4e-48 165.9 20.4 2.7 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 KSA02879.1 - 9.5e-54 181.6 0.1 1.1e-25 90.7 0.1 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KSA02879.1 - 4.5e-16 59.0 9.9 9.2e-06 25.2 1.6 4.3 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KSA02879.1 - 1.5e-11 44.7 10.1 0.00011 22.1 0.2 4.3 4 1 0 5 5 5 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KSA02879.1 - 1.7e-09 38.1 2.5 0.00077 19.7 0.3 4.1 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KSA02879.1 - 3.6e-09 36.2 1.3 0.0014 18.3 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KSA02879.1 - 3.9e-08 34.0 0.1 0.0014 19.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KSA02879.1 - 5.6e-07 30.2 0.3 0.068 13.7 0.0 3.1 3 1 0 3 3 2 2 AAA domain AAA_16 PF13191.6 KSA02879.1 - 3.2e-06 27.6 0.0 0.079 13.3 0.0 3.0 3 0 0 3 3 2 2 AAA ATPase domain IstB_IS21 PF01695.17 KSA02879.1 - 3.4e-06 26.9 0.5 0.36 10.6 0.0 4.3 4 0 0 4 4 4 1 IstB-like ATP binding protein RsgA_GTPase PF03193.16 KSA02879.1 - 7.4e-06 26.0 0.0 0.13 12.2 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase Sigma54_activ_2 PF14532.6 KSA02879.1 - 1.1e-05 25.6 0.0 0.14 12.3 0.0 3.1 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_15 PF13175.6 KSA02879.1 - 1.7e-05 24.7 10.0 0.00019 21.3 2.1 3.5 2 2 0 2 2 2 1 AAA ATPase domain AAA_13 PF13166.6 KSA02879.1 - 2.9e-05 22.9 8.5 0.018 13.8 0.1 3.3 4 0 0 4 4 4 2 AAA domain AAA_30 PF13604.6 KSA02879.1 - 6.6e-05 22.7 0.0 0.49 10.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 KSA02879.1 - 0.00032 20.7 0.0 0.44 10.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) APS_kinase PF01583.20 KSA02879.1 - 0.0007 19.5 0.0 0.86 9.5 0.0 2.5 2 0 0 2 2 2 2 Adenylylsulphate kinase Zeta_toxin PF06414.12 KSA02879.1 - 0.00079 18.8 0.0 0.038 13.3 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_14 PF13173.6 KSA02879.1 - 0.00093 19.2 0.4 1.5 8.8 0.0 3.3 3 0 0 3 3 2 1 AAA domain Sigma54_activat PF00158.26 KSA02879.1 - 0.0011 18.7 0.0 0.61 9.8 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain Rad17 PF03215.15 KSA02879.1 - 0.0018 18.2 0.0 0.34 10.8 0.0 2.9 2 0 0 2 2 2 1 Rad17 P-loop domain DUF3481 PF11980.8 KSA02879.1 - 0.0032 17.2 2.5 0.024 14.3 0.1 3.2 2 0 0 2 2 2 1 C-terminal domain of neuropilin glycoprotein RNA_helicase PF00910.22 KSA02879.1 - 0.0043 17.4 0.2 1.2 9.6 0.0 3.3 4 0 0 4 4 2 1 RNA helicase PRK PF00485.18 KSA02879.1 - 0.0045 16.7 0.0 0.61 9.8 0.0 2.5 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family DUF87 PF01935.17 KSA02879.1 - 0.0052 16.9 0.5 1.7 8.7 0.1 2.9 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_33 PF13671.6 KSA02879.1 - 0.0066 16.6 0.0 0.43 10.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 KSA02879.1 - 0.0085 15.2 0.0 3.3 6.7 0.0 2.5 3 0 0 3 3 2 1 Type II/IV secretion system protein ATP_bind_1 PF03029.17 KSA02879.1 - 0.01 15.7 0.0 5.9 6.6 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein PhoH PF02562.16 KSA02879.1 - 0.017 14.6 0.1 5.3 6.4 0.0 2.9 3 0 0 3 3 3 0 PhoH-like protein AAA_24 PF13479.6 KSA02879.1 - 0.018 14.8 0.0 6.8 6.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain ABC_ATPase PF09818.9 KSA02879.1 - 0.026 13.3 0.0 0.16 10.7 0.0 2.2 3 0 0 3 3 3 0 Predicted ATPase of the ABC class AAA_7 PF12775.7 KSA02879.1 - 0.028 13.9 0.1 5.8 6.4 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region NB-ARC PF00931.22 KSA02879.1 - 0.039 13.1 0.0 6.5 5.9 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain Baculo_gp41 PF04700.12 KSA02879.1 - 0.055 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Structural glycoprotein p40/gp41 conserved region NTPase_1 PF03266.15 KSA02879.1 - 0.066 13.1 1.5 7.3 6.5 0.0 3.3 3 0 0 3 3 3 0 NTPase CbiA PF01656.23 KSA02879.1 - 0.066 13.3 0.3 2.8 8.0 0.0 2.8 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Cytidylate_kin PF02224.18 KSA02879.1 - 0.08 12.7 3.6 4.1 7.1 0.3 3.0 3 1 0 3 3 2 0 Cytidylate kinase MMR_HSR1 PF01926.23 KSA02879.1 - 0.12 12.4 0.8 12 6.0 0.0 2.8 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_25 PF13481.6 KSA02879.1 - 0.17 11.4 0.0 6.4 6.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KSA02879.1 - 0.27 11.1 1.2 9.8 6.1 0.1 2.9 3 0 0 3 3 3 0 NACHT domain Brr6_like_C_C PF10104.9 KSA02880.1 - 2.1e-47 160.2 0.7 3.5e-47 159.5 0.7 1.4 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Baculo_PEP_C PF04513.12 KSA02880.1 - 0.021 14.9 1.2 0.047 13.7 1.2 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1672 PF07901.11 KSA02880.1 - 1.1 8.5 12.1 5.2 6.3 4.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1672) UDG PF03167.19 KSA02881.1 - 7.7e-11 42.2 0.0 2.5e-10 40.6 0.0 1.8 1 1 0 1 1 1 1 Uracil DNA glycosylase superfamily DUF1280 PF06918.14 KSA02882.1 - 0.005 16.5 0.3 0.0095 15.6 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1280) MRG PF05712.13 KSA02882.1 - 0.014 14.7 1.2 0.058 12.7 0.3 1.9 2 0 0 2 2 2 0 MRG DUF2267 PF10025.9 KSA02882.1 - 0.067 13.5 0.0 0.097 12.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) Pex19 PF04614.12 KSA02882.1 - 0.33 10.7 3.7 0.23 11.2 1.9 1.6 2 0 0 2 2 2 0 Pex19 protein family Cmc1 PF08583.10 KSA02882.1 - 1.5 8.9 8.7 0.37 10.9 2.8 2.4 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like TFB6 PF17110.5 KSA02883.1 - 2.3e-13 50.2 5.1 4.5e-13 49.3 0.2 2.1 2 0 0 2 2 2 2 Subunit 11 of the general transcription factor TFIIH Vac_ImportDeg PF09783.9 KSA02884.1 - 9.2e-59 197.9 2.8 1.8e-58 196.9 2.8 1.5 1 0 0 1 1 1 1 Vacuolar import and degradation protein PEMT PF04191.13 KSA02885.1 - 1.2e-32 112.4 3.2 1.2e-32 112.4 3.2 1.7 2 0 0 2 2 2 1 Phospholipid methyltransferase MFS_1 PF07690.16 KSA02886.1 - 8.6e-31 107.1 39.5 3.1e-27 95.4 20.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_3_6 PF07332.11 KSA02886.1 - 0.079 13.0 0.0 0.079 13.0 0.0 4.1 4 1 1 5 5 5 0 Putative Actinobacterial Holin-X, holin superfamily III Baseplate_J PF04865.14 KSA02886.1 - 0.11 11.6 0.8 0.17 11.0 0.8 1.2 1 0 0 1 1 1 0 Baseplate J-like protein Sugar_tr PF00083.24 KSA02887.1 - 7e-38 130.6 20.5 1.5e-37 129.5 20.5 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KSA02887.1 - 4.5e-37 127.8 14.1 5.5e-26 91.3 8.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KSA02887.1 - 0.00013 20.6 5.7 0.055 11.9 0.3 2.2 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Spore_YhaL PF14147.6 KSA02887.1 - 0.12 12.0 0.2 0.45 10.2 0.2 2.0 1 0 0 1 1 1 0 Sporulation protein YhaL Presenilin PF01080.17 KSA02887.1 - 0.4 9.4 2.4 0.7 8.6 2.4 1.3 1 0 0 1 1 1 0 Presenilin Sacchrp_dh_C PF16653.5 KSA02888.1 - 4.1e-94 315.6 0.0 1e-93 314.3 0.0 1.6 1 1 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Tubulin_3 PF14881.6 KSA02889.1 - 3.9e-25 88.6 0.1 8e-25 87.6 0.1 1.5 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.9 KSA02889.1 - 9.8e-16 58.1 3.1 1.2e-15 57.8 0.8 2.4 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin PF00091.25 KSA02889.1 - 0.0042 17.3 2.2 0.15 12.3 0.0 3.1 3 0 0 3 3 3 1 Tubulin/FtsZ family, GTPase domain DnaJ PF00226.31 KSA02890.1 - 2.1e-25 88.6 3.6 3.6e-25 87.9 3.6 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_C PF01556.18 KSA02890.1 - 1.1e-22 80.7 0.0 1.5e-22 80.3 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 KSA02890.1 - 4.4e-14 52.6 19.6 6.9e-14 52.0 19.6 1.3 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KSA02890.1 - 0.0002 21.3 10.9 0.029 14.3 0.9 2.6 2 1 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 KSA02890.1 - 0.016 15.2 6.0 1.4 8.9 0.8 2.2 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF1272 PF06906.11 KSA02890.1 - 0.66 10.1 7.9 0.094 12.8 3.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1272) FYVE PF01363.21 KSA02890.1 - 0.92 9.7 10.4 0.81 9.9 3.4 2.3 2 0 0 2 2 2 0 FYVE zinc finger NOB1_Zn_bind PF08772.11 KSA02890.1 - 4.7 7.4 12.4 21 5.4 3.6 2.4 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like C1_2 PF03107.16 KSA02890.1 - 4.7 7.6 9.1 5 7.5 1.0 2.4 2 0 0 2 2 2 0 C1 domain TackOD1 PF18551.1 KSA02890.1 - 6.6 6.4 12.2 9.2 5.9 2.7 2.2 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 HTH_45 PF14947.6 KSA02891.1 - 0.088 12.8 1.1 0.25 11.4 0.2 2.2 2 0 0 2 2 2 0 Winged helix-turn-helix PIG-X PF08320.12 KSA02892.1 - 1.4e-46 159.1 0.0 4.7e-46 157.4 0.0 1.8 2 0 0 2 2 2 1 PIG-X / PBN1 Gly_transf_sug PF04488.15 KSA02893.1 - 3.7e-15 56.3 0.1 1.4e-14 54.5 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif NMT1_3 PF16868.5 KSA02893.1 - 0.086 12.2 0.1 3.8 6.8 0.0 2.3 2 0 0 2 2 2 0 NMT1-like family LptF_LptG PF03739.14 KSA02893.1 - 1.5 7.5 4.4 1.2 7.9 2.1 2.0 2 1 0 2 2 2 0 Lipopolysaccharide export system permease LptF/LptG Mog1 PF04603.12 KSA02894.1 - 2.1e-29 102.7 2.7 5.4e-28 98.1 2.7 2.0 1 1 0 1 1 1 1 Ran-interacting Mog1 protein DUF2895 PF11444.8 KSA02895.1 - 0.11 11.9 0.4 1 8.7 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2895) Adaptin_N PF01602.20 KSA02896.1 - 1e-115 387.3 15.0 1.3e-115 386.9 15.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KSA02896.1 - 1.6e-60 203.8 2.4 1.6e-60 203.8 2.4 3.2 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KSA02896.1 - 4.4e-11 42.1 0.8 0.011 15.9 0.0 6.0 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.6 KSA02896.1 - 1.6e-10 41.3 0.0 2.2e-06 28.0 0.0 4.2 2 1 1 4 4 4 2 HEAT repeats HEAT_EZ PF13513.6 KSA02896.1 - 0.00025 21.5 0.0 0.61 10.7 0.0 4.1 3 0 0 3 3 3 1 HEAT-like repeat Arm PF00514.23 KSA02896.1 - 0.011 15.8 1.0 0.61 10.2 0.0 3.9 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 KSA02896.1 - 0.073 13.1 1.0 12 6.0 0.0 3.5 3 1 0 3 3 3 0 Spinocerebellar ataxia type 10 protein domain Med7 PF05983.11 KSA02897.1 - 7.5e-62 208.8 1.9 1.1e-61 208.2 1.9 1.3 1 0 0 1 1 1 1 MED7 protein Lge1 PF11488.8 KSA02897.1 - 0.056 13.6 3.1 0.17 12.1 0.2 2.6 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 Spc42p PF11544.8 KSA02897.1 - 1.3 9.1 12.5 0.042 13.8 5.4 2.1 2 0 0 2 2 2 0 Spindle pole body component Spc42p PDT PF00800.18 KSA02898.1 - 5.1e-63 212.2 0.1 6.9e-63 211.8 0.1 1.2 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.25 KSA02898.1 - 3.7e-11 42.6 0.0 1e-10 41.2 0.0 1.8 2 0 0 2 2 2 1 ACT domain Pam17 PF08566.10 KSA02899.1 - 3.2e-59 199.5 0.0 3.8e-59 199.2 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 BPD_transp_2 PF02653.16 KSA02899.1 - 0.0037 16.5 0.1 0.0048 16.1 0.1 1.1 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component SNF2_N PF00176.23 KSA02900.1 - 1.8e-71 240.7 0.7 5.1e-71 239.2 0.7 1.8 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KSA02900.1 - 3.1e-23 82.3 1.5 1.7e-19 70.2 0.0 3.8 3 0 0 3 3 3 2 Helicase conserved C-terminal domain Bromodomain PF00439.25 KSA02900.1 - 6.9e-21 74.1 0.6 2.8e-20 72.2 0.6 2.1 1 0 0 1 1 1 1 Bromodomain ResIII PF04851.15 KSA02900.1 - 1.6e-14 54.2 0.4 1.6e-14 54.2 0.4 4.2 5 1 0 5 5 5 1 Type III restriction enzyme, res subunit HSA PF07529.13 KSA02900.1 - 2.5e-11 43.7 5.5 1.3e-10 41.5 5.5 2.4 1 0 0 1 1 1 1 HSA SnAC PF14619.6 KSA02900.1 - 1.1e-08 35.6 1.3 1.1e-08 35.6 1.3 4.2 4 2 2 6 6 6 1 Snf2-ATP coupling, chromatin remodelling complex PKcGMP_CC PF16808.5 KSA02900.1 - 0.58 10.1 7.9 1.6 8.6 0.3 4.7 5 0 0 5 5 5 0 Coiled-coil N-terminus of cGMP-dependent protein kinase peroxidase PF00141.23 KSA02902.1 - 4.1e-34 118.3 0.0 6.5e-34 117.6 0.0 1.3 1 1 0 1 1 1 1 Peroxidase Toxin_28 PF08115.11 KSA02902.1 - 0.16 11.9 1.5 0.33 10.9 1.5 1.4 1 0 0 1 1 1 0 SFI toxin family Ribosomal_L6 PF00347.23 KSA02903.1 - 2.5e-28 98.5 8.7 8.3e-15 55.2 3.0 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 BT1 PF03092.16 KSA02903.1 - 0.14 10.4 0.2 0.15 10.3 0.2 1.0 1 0 0 1 1 1 0 BT1 family YbbR PF07949.12 KSA02903.1 - 0.15 12.4 3.1 0.42 11.0 0.2 2.8 1 1 1 3 3 3 0 YbbR-like protein Transket_pyr PF02779.24 KSA02904.1 - 4e-66 222.1 0.0 1.2e-65 220.5 0.0 1.8 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 KSA02904.1 - 1.3e-57 195.0 0.0 1.8e-57 194.6 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 KSA02904.1 - 2.8e-53 179.7 0.0 4.6e-53 179.0 0.0 1.3 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 KSA02904.1 - 8.7e-18 63.6 3.9 8.7e-18 63.6 3.9 1.9 2 0 0 2 2 2 1 2-oxoglutarate dehydrogenase N-terminus baeRF_family12 PF18856.1 KSA02904.1 - 0.21 12.2 2.1 1.4 9.5 0.1 2.6 3 0 0 3 3 3 0 Bacterial archaeo-eukaryotic release factor family 12 FAD_binding_3 PF01494.19 KSA02905.1 - 1.4e-16 60.7 0.0 3.8e-16 59.3 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 KSA02905.1 - 3.2e-06 26.3 2.7 0.02 13.7 0.0 2.7 2 1 1 3 3 3 2 Tryptophan halogenase NAD_binding_8 PF13450.6 KSA02905.1 - 4.1e-06 26.9 0.5 9e-06 25.8 0.1 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KSA02905.1 - 5.1e-05 22.5 1.3 9e-05 21.7 1.3 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KSA02905.1 - 5.4e-05 22.7 0.0 8.6e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KSA02905.1 - 0.00011 21.1 1.0 0.00088 18.1 1.0 1.9 1 1 0 1 1 1 1 HI0933-like protein SE PF08491.10 KSA02905.1 - 0.00015 20.9 0.0 0.00047 19.3 0.0 1.7 2 0 0 2 2 2 1 Squalene epoxidase Pyr_redox_2 PF07992.14 KSA02905.1 - 0.0002 20.7 0.8 0.0044 16.3 0.2 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KSA02905.1 - 0.0005 19.8 2.1 0.012 15.3 1.5 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KSA02905.1 - 0.015 15.9 2.2 0.13 12.8 0.5 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KSA02905.1 - 0.025 13.7 3.0 0.049 12.7 3.0 1.6 1 1 0 1 1 1 0 Glucose inhibited division protein A Thi4 PF01946.17 KSA02905.1 - 0.25 10.6 1.0 0.44 9.8 0.2 1.7 2 0 0 2 2 2 0 Thi4 family Pyr_redox_3 PF13738.6 KSA02905.1 - 0.88 8.8 3.5 2.7 7.1 3.5 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_dh_N PF08501.11 KSA02906.1 - 4.5e-17 62.1 0.1 1.5e-16 60.4 0.1 2.0 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain DHquinase_I PF01487.15 KSA02906.1 - 2.6e-14 54.0 0.0 2.2e-13 51.0 0.0 2.1 2 0 0 2 2 2 1 Type I 3-dehydroquinase Shikimate_DH PF01488.20 KSA02906.1 - 1.1e-08 35.2 0.0 3e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase SKI PF01202.22 KSA02906.1 - 4.8e-07 30.0 0.1 4.2e-06 27.0 0.0 2.2 2 0 0 2 2 2 1 Shikimate kinase AAA_16 PF13191.6 KSA02906.1 - 0.042 14.2 0.0 0.087 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 KSA02906.1 - 0.18 12.4 0.0 0.37 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF676 PF05057.14 KSA02907.1 - 7.8e-42 143.2 0.0 1.4e-41 142.4 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) LCAT PF02450.15 KSA02907.1 - 0.0023 17.2 0.1 0.0066 15.7 0.0 1.7 2 0 0 2 2 2 1 Lecithin:cholesterol acyltransferase Abhydrolase_2 PF02230.16 KSA02907.1 - 0.056 13.3 0.1 0.14 11.9 0.1 1.7 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase PGAP1 PF07819.13 KSA02907.1 - 0.11 12.1 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein adh_short PF00106.25 KSA02908.1 - 2.7e-43 147.7 0.0 3.3e-43 147.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KSA02908.1 - 1.5e-29 103.2 0.0 1.9e-29 102.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KSA02908.1 - 0.00012 22.1 0.0 0.00022 21.2 0.0 1.4 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KSA02908.1 - 0.0073 16.2 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KSA02908.1 - 0.013 14.9 0.0 0.075 12.5 0.0 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.8 KSA02908.1 - 0.021 14.6 0.0 0.053 13.3 0.0 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase APG6_N PF17675.1 KSA02909.1 - 0.014 15.9 4.0 0.014 15.9 4.0 5.0 2 2 3 5 5 5 0 Apg6 coiled-coil region DUF2316 PF10078.9 KSA02909.1 - 1.2 9.4 15.4 3.6 7.9 2.1 4.2 3 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2316) Cnn_1N PF07989.11 KSA02910.1 - 0.00018 21.6 4.3 0.00018 21.6 4.3 2.2 2 0 0 2 2 2 1 Centrosomin N-terminal motif 1 Ax_dynein_light PF10211.9 KSA02910.1 - 0.00019 21.4 7.2 0.00022 21.2 7.2 1.1 1 0 0 1 1 1 1 Axonemal dynein light chain GIT_CC PF16559.5 KSA02910.1 - 0.00069 19.4 5.4 0.0014 18.5 5.4 1.5 1 0 0 1 1 1 1 GIT coiled-coil Rho guanine nucleotide exchange factor GOLGA2L5 PF15070.6 KSA02910.1 - 0.00095 17.9 5.2 0.0011 17.8 5.2 1.0 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 RcbX PF02341.15 KSA02910.1 - 0.012 15.9 0.4 0.015 15.5 0.4 1.3 1 0 0 1 1 1 0 RbcX protein APG6_N PF17675.1 KSA02910.1 - 0.018 15.5 5.2 0.021 15.3 4.6 1.4 1 1 0 1 1 1 0 Apg6 coiled-coil region HemX PF04375.14 KSA02910.1 - 0.031 13.6 2.9 0.037 13.3 2.9 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase FlaC_arch PF05377.11 KSA02910.1 - 0.033 14.6 1.7 0.033 14.6 1.7 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) TMF_TATA_bd PF12325.8 KSA02910.1 - 0.04 14.1 8.7 0.34 11.1 3.8 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF724 PF05266.14 KSA02910.1 - 0.2 11.4 6.6 0.27 11.0 6.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF724) DUF4407 PF14362.6 KSA02910.1 - 0.3 10.4 1.7 0.31 10.4 1.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CENP-H PF05837.12 KSA02910.1 - 0.31 11.5 6.4 0.21 12.0 5.0 1.6 1 1 0 1 1 1 0 Centromere protein H (CENP-H) Jnk-SapK_ap_N PF09744.9 KSA02910.1 - 0.52 10.5 9.3 0.84 9.8 9.2 1.5 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF641 PF04859.12 KSA02910.1 - 0.72 10.2 6.2 1.1 9.6 6.2 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) ZapB PF06005.12 KSA02910.1 - 1 9.8 10.2 0.33 11.4 4.8 2.2 1 1 0 2 2 2 0 Cell division protein ZapB DivIC PF04977.15 KSA02910.1 - 1 9.2 7.5 0.096 12.5 1.4 2.2 2 1 1 3 3 3 0 Septum formation initiator Rho_Binding PF08912.11 KSA02910.1 - 1.2 10.0 11.9 0.6 11.0 4.6 2.2 1 1 1 2 2 2 0 Rho Binding XhlA PF10779.9 KSA02910.1 - 5.9 7.2 8.4 1.1 9.4 3.8 2.1 2 0 0 2 2 2 0 Haemolysin XhlA KELK PF15796.5 KSA02910.1 - 6.6 7.3 12.0 2.3 8.7 6.8 2.4 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF836 PF05768.14 KSA02911.1 - 5e-13 49.3 0.2 6e-13 49.0 0.2 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.24 KSA02911.1 - 0.00047 20.3 0.4 0.0014 18.8 0.4 1.8 1 1 0 1 1 1 1 Glutaredoxin SSXT PF05030.12 KSA02912.1 - 0.012 15.2 1.1 0.33 10.6 0.0 3.2 2 0 0 2 2 2 0 SSXT protein (N-terminal region) ANAPC2 PF08672.11 KSA02912.1 - 0.04 14.4 0.3 0.17 12.4 0.3 2.1 1 0 0 1 1 1 0 Anaphase promoting complex (APC) subunit 2 DUF4446 PF14584.6 KSA02912.1 - 4 7.4 11.0 0.78 9.7 3.0 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) Organ_specific PF10950.8 KSA02913.1 - 3.4 8.4 7.1 0.62 10.8 2.5 2.0 2 0 0 2 2 2 0 Organ specific protein ANAPC4_WD40 PF12894.7 KSA02914.1 - 2.8e-08 33.9 0.0 0.15 12.4 0.0 3.7 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KSA02914.1 - 7.8e-06 26.5 7.1 0.00041 21.1 0.3 4.6 5 0 0 5 5 5 1 WD domain, G-beta repeat Nup160 PF11715.8 KSA02914.1 - 0.00029 19.6 0.1 0.77 8.3 0.0 2.8 2 1 1 3 3 3 2 Nucleoporin Nup120/160 IKI3 PF04762.12 KSA02914.1 - 0.021 12.9 0.0 0.033 12.2 0.0 1.2 1 0 0 1 1 1 0 IKI3 family eIF2A PF08662.11 KSA02914.1 - 0.03 14.2 0.0 0.2 11.5 0.0 2.6 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Lactonase PF10282.9 KSA02914.1 - 0.069 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller DUF1533 PF07550.11 KSA02914.1 - 0.096 12.6 0.5 0.47 10.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1533) adh_short_C2 PF13561.6 KSA02915.1 - 8.5e-47 159.7 0.0 1.1e-46 159.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KSA02915.1 - 1.6e-43 148.4 0.0 2.1e-43 148.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KSA02915.1 - 2.3e-09 37.4 0.0 2.9e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KSA02915.1 - 0.02 14.0 0.0 0.027 13.6 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein RnlB_antitoxin PF15933.5 KSA02915.1 - 0.35 11.2 2.0 3.4 8.0 0.2 2.5 2 1 1 3 3 3 0 Antitoxin to bacterial toxin RNase LS or RnlA tRNA-synt_1 PF00133.22 KSA02917.1 - 4.6e-52 177.1 0.4 1.6e-30 105.9 0.9 6.2 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 KSA02917.1 - 1.4e-43 148.6 0.0 2.4e-43 147.8 0.0 1.4 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 KSA02917.1 - 1.6e-28 99.6 0.3 6.2e-20 71.3 0.0 5.2 4 1 1 5 5 5 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 KSA02917.1 - 1.2e-13 51.3 0.5 2.6e-13 50.2 0.5 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 KSA02917.1 - 0.00013 21.4 0.0 0.34 10.2 0.0 2.7 2 1 1 3 3 3 2 tRNA synthetases class I (C) catalytic domain Zn-ribbon_8 PF09723.10 KSA02917.1 - 0.077 13.1 0.3 0.34 11.0 0.0 2.2 2 0 0 2 2 2 0 Zinc ribbon domain PPR_2 PF13041.6 KSA02918.1 - 1.4e-15 57.2 9.2 1e-08 35.2 0.3 5.0 3 1 2 5 5 5 3 PPR repeat family PPR PF01535.20 KSA02918.1 - 1.1e-12 47.3 3.7 0.0038 17.4 0.3 5.3 4 0 0 4 4 4 3 PPR repeat PPR_long PF17177.4 KSA02918.1 - 1.7e-10 40.6 1.9 6.9e-08 32.1 0.2 3.4 3 2 2 5 5 5 2 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 KSA02918.1 - 6.8e-08 32.5 6.8 1.1e-06 28.6 0.2 4.0 3 1 2 5 5 5 1 Pentatricopeptide repeat domain ATP13 PF12921.7 KSA02918.1 - 0.00025 20.9 0.8 0.051 13.4 0.7 3.5 2 1 0 2 2 2 1 Mitochondrial ATPase expression ERAP1_C PF11838.8 KSA02918.1 - 0.0015 18.2 0.3 0.016 14.8 0.0 2.3 2 1 0 2 2 2 1 ERAP1-like C-terminal domain PPR_1 PF12854.7 KSA02918.1 - 0.0043 16.7 1.9 34 4.2 0.0 4.5 4 1 0 4 4 4 0 PPR repeat ANAPC3 PF12895.7 KSA02918.1 - 0.082 13.1 0.1 3.4 8.0 0.0 3.0 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 AMP-binding PF00501.28 KSA02919.1 - 3.7e-55 187.2 0.0 3.5e-32 111.6 0.0 3.3 2 2 0 2 2 2 2 AMP-binding enzyme Nup_retrotrp_bd PF10599.9 KSA02920.1 - 1.4e-22 80.1 7.7 1.4e-22 80.1 7.7 9.7 2 1 4 6 6 6 1 Retro-transposon transporting motif CRAL_TRIO PF00650.20 KSA02921.1 - 1e-36 126.1 0.0 3e-36 124.5 0.0 1.8 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 KSA02921.1 - 1.6e-07 31.5 0.0 3.4e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KSA02921.1 - 1.5e-06 28.3 0.4 4.5e-06 26.8 0.4 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain PHD PF00628.29 KSA02922.1 - 1e-08 34.9 2.6 1e-08 34.9 2.6 1.9 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 KSA02922.1 - 0.27 10.8 4.4 0.46 10.1 4.4 1.4 1 0 0 1 1 1 0 PHD-finger DUF3827 PF12877.7 KSA02922.1 - 1.1 7.5 15.2 1.5 7.1 15.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Sec1 PF00995.23 KSA02923.1 - 6e-102 342.7 38.5 7e-102 342.5 38.5 1.0 1 0 0 1 1 1 1 Sec1 family Syntaxin-18_N PF10496.9 KSA02923.1 - 0.022 15.0 1.4 0.13 12.5 1.4 2.4 1 0 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus NOG1 PF06858.14 KSA02923.1 - 0.18 11.6 1.4 5.3 6.9 0.0 3.5 3 0 0 3 3 3 0 Nucleolar GTP-binding protein 1 (NOG1) Peptidase_M16_M PF16187.5 KSA02924.1 - 6.3e-80 268.4 7.5 6.3e-80 268.4 7.5 2.1 2 0 0 2 2 2 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 KSA02924.1 - 3e-40 137.6 0.2 8.6e-40 136.1 0.2 1.9 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KSA02924.1 - 2e-33 115.9 2.1 2e-18 67.0 0.0 2.8 3 0 0 3 3 3 2 Peptidase M16 inactive domain Uteroglobin PF01099.17 KSA02924.1 - 0.11 12.9 0.8 0.62 10.4 0.8 2.3 1 0 0 1 1 1 0 Uteroglobin family PYRIN PF02758.16 KSA02924.1 - 8.1 6.7 6.7 5.6 7.2 1.6 3.2 2 1 0 2 2 2 0 PAAD/DAPIN/Pyrin domain Rogdi_lz PF10259.9 KSA02925.1 - 9.2e-70 235.2 2.2 1.1e-69 234.9 2.2 1.1 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein TMEM43 PF07787.12 KSA02926.1 - 2.1 7.7 15.3 0.13 11.6 8.3 2.1 2 0 0 2 2 2 0 Transmembrane protein 43 DUF4396 PF14342.6 KSA02927.1 - 0.13 12.6 0.5 0.29 11.5 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4396) LEA_2 PF03168.13 KSA02927.1 - 0.15 12.6 0.0 27 5.4 0.0 3.4 3 0 0 3 3 3 0 Late embryogenesis abundant protein CFEM PF05730.11 KSA02928.1 - 5.9e-10 39.1 11.1 1.4e-09 37.9 11.1 1.7 1 0 0 1 1 1 1 CFEM domain GREB1 PF15782.5 KSA02928.1 - 1.1 6.2 23.7 1.3 6.1 23.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SOG2 PF10428.9 KSA02928.1 - 8.4 5.5 30.2 13 4.8 30.2 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Amidohydro_1 PF01979.20 KSA02929.1 - 1.2e-65 222.1 0.0 1.5e-65 221.8 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KSA02929.1 - 2.9e-06 27.0 0.0 0.00085 18.9 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family SMC_N PF02463.19 KSA02930.1 - 5.6e-16 58.6 43.6 4.6e-14 52.4 43.6 3.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KSA02930.1 - 1.1e-07 32.6 41.6 1.1e-07 32.6 41.6 5.3 2 2 1 3 3 3 1 AAA domain AAA_15 PF13175.6 KSA02930.1 - 3.3e-06 27.1 41.1 3.3e-06 27.1 41.1 4.0 2 2 1 3 3 3 1 AAA ATPase domain AAA_21 PF13304.6 KSA02930.1 - 0.0051 16.7 7.5 0.0051 16.7 7.5 4.1 2 2 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KSA02930.1 - 0.03 14.1 0.0 0.071 12.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain NPV_P10 PF05531.12 KSA02930.1 - 3.3 8.2 27.2 1.1 9.8 0.4 5.6 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein DER1 PF04511.15 KSA02931.1 - 0.041 13.8 0.3 0.12 12.2 0.0 1.8 2 0 0 2 2 2 0 Der1-like family PPR PF01535.20 KSA02931.1 - 0.097 13.0 0.1 7.3 7.1 0.0 3.3 3 0 0 3 3 3 0 PPR repeat FANCI_S3 PF14677.6 KSA02931.1 - 0.36 10.5 7.4 1.3 8.6 0.4 2.5 2 0 0 2 2 2 0 FANCI solenoid 3 60KD_IMP PF02096.20 KSA02932.1 - 9.5e-25 87.4 2.8 9.5e-25 87.4 2.8 1.7 3 0 0 3 3 3 1 60Kd inner membrane protein IQCJ-SCHIP1 PF15157.6 KSA02932.1 - 0.024 14.5 0.1 0.072 12.9 0.0 1.9 2 0 0 2 2 2 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif EMC3_TMCO1 PF01956.16 KSA02932.1 - 0.45 10.2 14.1 0.1 12.3 8.7 2.5 2 1 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like RhoGAP PF00620.27 KSA02933.1 - 3.3e-35 121.2 0.2 3.3e-35 121.2 0.2 2.6 3 0 0 3 3 3 1 RhoGAP domain RasGEF_N PF00618.20 KSA02933.1 - 3.5e-16 59.3 3.8 3.2e-15 56.2 3.8 2.8 1 0 0 1 1 1 1 RasGEF N-terminal motif RasGEF PF00617.19 KSA02933.1 - 7.2e-15 55.6 8.7 2.7e-13 50.5 0.2 4.2 3 2 0 3 3 3 2 RasGEF domain PH PF00169.29 KSA02933.1 - 0.01 16.4 0.0 0.081 13.4 0.0 2.5 1 1 0 1 1 1 0 PH domain tRNA-synt_2 PF00152.20 KSA02934.1 - 3e-69 233.5 0.0 4e-69 233.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KSA02934.1 - 6.2e-08 32.5 0.0 1.4e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KSA02934.1 - 7.4e-06 25.6 0.8 0.0021 17.6 0.0 2.6 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) tRNA_anti_2 PF13742.6 KSA02934.1 - 0.1 12.8 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain Sec23_trunk PF04811.15 KSA02935.1 - 3.5e-49 167.6 0.1 1e-47 162.8 0.1 2.2 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 KSA02935.1 - 4.8e-32 110.6 0.0 1.2e-31 109.3 0.0 1.8 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 KSA02935.1 - 2.2e-23 82.0 0.1 7.2e-23 80.4 0.0 1.9 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Gelsolin PF00626.22 KSA02935.1 - 1e-10 41.3 0.0 3.2e-10 39.8 0.0 1.9 2 0 0 2 2 2 1 Gelsolin repeat zf-Sec23_Sec24 PF04810.15 KSA02935.1 - 1.2e-09 38.1 4.0 2.6e-09 37.0 4.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger zinc_ribbon_10 PF10058.9 KSA02935.1 - 0.13 12.0 0.7 0.3 10.8 0.7 1.6 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein PHD PF00628.29 KSA02935.1 - 0.27 11.2 2.6 0.72 9.8 2.6 1.7 1 1 0 1 1 1 0 PHD-finger TPP1 PF10341.9 KSA02936.1 - 0.15 12.1 2.1 5.2 7.1 0.0 2.7 2 1 0 3 3 3 0 Shelterin complex subunit, TPP1/ACD YEATS PF03366.16 KSA02937.1 - 1.2e-29 102.1 1.7 2.5e-29 101.1 1.7 1.5 1 0 0 1 1 1 1 YEATS family PTR2 PF00854.21 KSA02938.1 - 6e-56 190.0 2.8 8.2e-56 189.5 2.8 1.1 1 0 0 1 1 1 1 POT family DUF3611 PF12263.8 KSA02938.1 - 0.046 13.6 9.1 0.48 10.3 0.3 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3611) Syja_N PF02383.18 KSA02939.1 - 8.5e-72 242.2 4.8 1.2e-71 241.7 1.2 2.2 2 0 0 2 2 2 1 SacI homology domain Exo_endo_phos PF03372.23 KSA02939.1 - 2.1e-10 40.6 0.0 4.4e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Tom7 PF08038.12 KSA02940.1 - 8.2e-22 76.6 0.1 1e-21 76.3 0.1 1.1 1 0 0 1 1 1 1 TOM7 family Mito_carr PF00153.27 KSA02941.1 - 2.4e-58 194.1 6.1 4e-20 71.5 0.0 3.6 2 1 1 3 3 3 3 Mitochondrial carrier protein RNase_HII PF01351.18 KSA02942.1 - 2.4e-54 184.2 0.0 3.2e-54 183.8 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease HII 2-oxoacid_dh PF00198.23 KSA02943.1 - 3.8e-75 252.3 0.6 4.8e-75 252.0 0.6 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KSA02943.1 - 1.6e-16 59.9 0.0 3.1e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 KSA02943.1 - 3e-14 53.0 0.2 7e-14 51.9 0.2 1.7 1 0 0 1 1 1 1 e3 binding domain His_Phos_1 PF00300.22 KSA02944.1 - 3.3e-18 66.1 0.0 1.3e-17 64.1 0.0 2.0 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) DUF4653 PF15546.6 KSA02944.1 - 0.016 14.9 0.5 0.023 14.3 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4653) TFIIIC_sub6 PF10419.9 KSA02945.1 - 5.8e-10 38.9 0.8 4.5e-05 23.2 0.0 2.3 1 1 1 2 2 2 2 TFIIIC subunit triple barrel domain Sarcoglycan_1 PF04790.13 KSA02945.1 - 0.068 12.5 4.8 0.094 12.1 4.8 1.3 1 1 0 1 1 1 0 Sarcoglycan complex subunit protein Maf PF02545.14 KSA02946.1 - 1.8e-31 109.2 0.0 2e-31 109.1 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein RRM_1 PF00076.22 KSA02947.1 - 8.2e-16 57.6 0.1 1.6e-15 56.7 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KSA02947.1 - 0.0029 17.2 0.1 0.0052 16.4 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mad3_BUB1_I_2 PF17014.5 KSA02947.1 - 0.068 13.3 1.2 0.13 12.4 1.2 1.5 1 0 0 1 1 1 0 Putative Mad3/BUB1 like region 1 protein Nop14 PF04147.12 KSA02947.1 - 0.088 11.0 17.5 0.12 10.5 17.5 1.2 1 0 0 1 1 1 0 Nop14-like family SAPS PF04499.15 KSA02947.1 - 0.11 11.3 5.4 0.17 10.7 5.4 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RRN3 PF05327.11 KSA02947.1 - 0.31 9.5 4.0 0.35 9.4 4.0 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 MFMR_assoc PF16596.5 KSA02947.1 - 0.44 11.0 8.3 0.95 9.9 8.3 1.6 1 0 0 1 1 1 0 Disordered region downstream of MFMR CobT PF06213.12 KSA02947.1 - 4.7 6.5 18.5 7.2 5.9 18.5 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Cyt-b5 PF00173.28 KSA02948.1 - 1e-23 83.3 0.2 1.3e-23 82.9 0.2 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NMO PF03060.15 KSA02949.1 - 6.2e-47 160.6 0.0 7.5e-47 160.3 0.0 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KSA02949.1 - 0.00094 18.3 0.0 0.1 11.6 0.0 2.2 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KSA02949.1 - 0.0024 17.0 0.0 0.0032 16.6 0.0 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DHO_dh PF01180.21 KSA02949.1 - 0.041 13.1 0.0 0.084 12.1 0.0 1.6 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase DNA_pol3_tau_5 PF12170.8 KSA02949.1 - 0.1 12.7 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III tau subunit V interacting with alpha His_biosynth PF00977.21 KSA02949.1 - 0.15 11.5 0.0 0.29 10.6 0.0 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein Methyltransf_PK PF05891.12 KSA02950.1 - 3.4e-76 255.6 0.0 3.9e-76 255.4 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 KSA02950.1 - 0.039 14.7 0.0 0.089 13.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Sld5 PF05916.11 KSA02951.1 - 4.7e-19 68.9 0.3 5.8e-19 68.6 0.3 1.1 1 0 0 1 1 1 1 GINS complex protein Peptidase_C33 PF05412.12 KSA02951.1 - 0.053 13.6 0.1 0.076 13.0 0.1 1.3 1 0 0 1 1 1 0 Equine arterivirus Nsp2-type cysteine proteinase PI_PP_I PF18363.1 KSA02951.1 - 0.93 9.7 4.3 10 6.4 0.3 2.9 1 1 0 3 3 3 0 Phosphoinositide phosphatase insertion domain TPR_2 PF07719.17 KSA02952.1 - 7e-22 75.7 13.8 0.014 15.5 0.1 11.9 13 0 0 13 13 12 6 Tetratricopeptide repeat TPR_1 PF00515.28 KSA02952.1 - 3.7e-21 74.0 24.2 0.00011 21.8 0.2 11.6 14 0 0 14 14 13 5 Tetratricopeptide repeat TPR_8 PF13181.6 KSA02952.1 - 7.1e-19 66.4 26.1 0.0066 16.6 0.1 14.0 13 0 0 13 13 13 4 Tetratricopeptide repeat TPR_19 PF14559.6 KSA02952.1 - 1.5e-17 63.8 3.2 8.7e-05 23.0 0.0 9.2 8 1 1 9 9 8 2 Tetratricopeptide repeat TPR_12 PF13424.6 KSA02952.1 - 4e-13 49.4 17.9 0.0084 16.4 0.0 9.8 11 1 0 12 12 11 4 Tetratricopeptide repeat TPR_6 PF13174.6 KSA02952.1 - 6.2e-12 45.3 3.8 8.5 7.3 0.0 10.9 11 0 0 11 11 11 1 Tetratricopeptide repeat TPR_16 PF13432.6 KSA02952.1 - 8.4e-12 45.5 0.0 0.0055 17.3 0.0 5.9 5 2 1 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 KSA02952.1 - 3.6e-11 42.9 0.0 10 7.3 0.0 9.1 7 2 2 9 9 8 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KSA02952.1 - 5.8e-08 32.9 17.7 0.00095 19.3 0.0 6.1 6 1 1 7 7 7 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 KSA02952.1 - 4e-06 26.4 15.7 1.3 8.8 0.2 9.1 9 2 2 11 11 11 2 TPR repeat TPR_10 PF13374.6 KSA02952.1 - 6.7e-06 25.8 0.2 19 5.3 0.0 7.5 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_17 PF13431.6 KSA02952.1 - 8.7e-06 25.8 25.3 0.18 12.3 0.6 9.9 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_7 PF13176.6 KSA02952.1 - 0.019 14.9 15.3 0.037 14.1 0.1 7.0 7 1 1 8 8 7 0 Tetratricopeptide repeat RHH_7 PF16777.5 KSA02952.1 - 1.2 9.6 9.9 1.9 8.9 0.2 3.9 4 0 0 4 4 2 0 Transcriptional regulator, RHH-like, CopG Spc7 PF08317.11 KSA02953.1 - 6.9e-69 232.1 16.2 6.9e-69 232.1 16.2 3.4 2 1 2 4 4 4 1 Spc7 kinetochore protein Spc7_C2 PF15577.6 KSA02953.1 - 5e-12 45.7 0.0 1.7e-11 44.0 0.0 2.0 1 0 0 1 1 1 1 Spc7_C2 TTRAP PF14203.6 KSA02953.1 - 0.059 13.3 0.4 0.059 13.3 0.4 2.4 2 0 0 2 2 2 0 Putative tranposon-transfer assisting protein Phage_DsbA PF11126.8 KSA02953.1 - 0.08 13.2 1.8 4 7.7 0.1 4.0 4 0 0 4 4 4 0 Transcriptional regulator DsbA PEX11 PF05648.14 KSA02954.1 - 7.2e-71 238.2 0.8 8.8e-71 237.9 0.8 1.1 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) FGAR-AT_N PF18076.1 KSA02954.1 - 0.16 12.0 0.1 2.5 8.1 0.1 2.1 2 0 0 2 2 2 0 Formylglycinamide ribonucleotide amidotransferase N-terminal Btz PF09405.10 KSA02956.1 - 0.2 11.9 11.3 1.1 9.5 11.3 2.2 1 0 0 1 1 1 0 CASC3/Barentsz eIF4AIII binding PI3K_1B_p101 PF10486.9 KSA02956.1 - 1.7 6.4 12.5 2.6 5.7 12.5 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit ALG3 PF05208.13 KSA02957.1 - 5.3e-123 411.0 22.4 7e-123 410.6 22.4 1.2 1 0 0 1 1 1 1 ALG3 protein LisH PF08513.11 KSA02958.1 - 3e-07 30.2 0.0 6.2e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 LisH WD40 PF00400.32 KSA02960.1 - 2.9e-20 72.2 1.8 0.00063 20.5 0.0 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KSA02960.1 - 1.2e-08 35.2 0.0 0.0082 16.4 0.0 4.6 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KSA02960.1 - 0.0024 16.9 0.3 0.15 11.0 0.0 2.9 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KSA02960.1 - 0.0029 17.0 0.0 0.0045 16.4 0.0 1.4 1 0 0 1 1 1 1 WD40-like domain Nup160 PF11715.8 KSA02960.1 - 0.0037 16.0 0.1 0.088 11.4 0.0 2.2 1 1 1 2 2 2 1 Nucleoporin Nup120/160 eIF2A PF08662.11 KSA02960.1 - 0.0041 17.0 0.2 0.32 10.8 0.0 2.9 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.11 KSA02960.1 - 0.021 13.6 0.6 0.74 8.5 0.0 2.3 2 1 0 2 2 2 0 Nup133 N terminal like Voltage_CLC PF00654.20 KSA02961.1 - 3e-72 243.8 15.1 5e-72 243.1 15.1 1.3 1 0 0 1 1 1 1 Voltage gated chloride channel Med17 PF10156.9 KSA02961.1 - 0.063 12.0 1.6 0.089 11.5 1.6 1.1 1 0 0 1 1 1 0 Subunit 17 of Mediator complex AAR2 PF05282.11 KSA02962.1 - 9.2e-68 229.2 0.4 1.1e-67 229.0 0.4 1.1 1 0 0 1 1 1 1 AAR2 protein Rad4 PF03835.15 KSA02962.1 - 0.048 13.3 0.0 0.083 12.6 0.0 1.4 1 0 0 1 1 1 0 Rad4 transglutaminase-like domain HMG_box PF00505.19 KSA02963.1 - 0.043 14.2 0.4 0.043 14.2 0.4 2.3 3 0 0 3 3 3 0 HMG (high mobility group) box Arrestin_C PF02752.22 KSA02964.1 - 1.2e-14 55.0 0.1 2.3e-13 50.8 0.0 2.3 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KSA02964.1 - 7.7e-05 22.8 0.0 0.013 15.6 0.0 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain EXS PF03124.14 KSA02965.1 - 1.8e-29 103.1 5.8 2.2e-29 102.9 5.8 1.1 1 0 0 1 1 1 1 EXS family Sars6 PF12133.8 KSA02965.1 - 0.057 13.4 0.8 0.33 10.9 0.1 2.4 2 0 0 2 2 2 0 Open reading frame 6 from SARS coronavirus DUF4611 PF15387.6 KSA02965.1 - 0.25 11.6 7.5 0.47 10.7 5.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) NOA36 PF06524.12 KSA02965.1 - 3.8 6.8 6.9 1.2 8.4 3.8 1.7 2 0 0 2 2 2 0 NOA36 protein Aldo_ket_red PF00248.21 KSA02966.1 - 5.8e-61 206.3 0.0 6.6e-61 206.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HMGL-like PF00682.19 KSA02967.1 - 5e-84 282.0 0.2 7e-84 281.5 0.2 1.2 1 0 0 1 1 1 1 HMGL-like FliG_N PF14842.6 KSA02967.1 - 0.087 13.4 0.0 0.19 12.3 0.0 1.5 1 0 0 1 1 1 0 FliG N-terminal domain Oxidored_FMN PF00724.20 KSA02967.1 - 0.11 11.7 0.3 0.64 9.2 0.1 2.2 2 1 0 2 2 2 0 NADH:flavin oxidoreductase / NADH oxidase family IATP PF04568.12 KSA02969.1 - 2.3e-10 40.8 8.9 6.2e-10 39.4 8.9 1.7 1 1 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP BLOC1_2 PF10046.9 KSA02969.1 - 0.0056 17.0 3.3 0.006 16.8 3.3 1.2 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fib_alpha PF08702.10 KSA02969.1 - 0.03 14.5 2.6 0.031 14.5 2.6 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family NPV_P10 PF05531.12 KSA02969.1 - 0.052 14.0 2.4 0.055 13.9 1.7 1.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Gon7 PF08738.10 KSA02969.1 - 0.063 13.4 3.0 0.82 9.8 0.1 2.1 1 1 1 2 2 2 0 Gon7 family Nup88 PF10168.9 KSA02969.1 - 0.17 9.7 5.6 0.16 9.7 5.6 1.0 1 0 0 1 1 1 0 Nuclear pore component DUF4140 PF13600.6 KSA02969.1 - 0.33 11.4 5.0 0.39 11.2 5.0 1.3 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Glutaredoxin2_C PF04399.13 KSA02969.1 - 0.34 10.8 3.1 0.78 9.6 3.1 1.7 1 1 0 1 1 1 0 Glutaredoxin 2, C terminal domain AAA_23 PF13476.6 KSA02969.1 - 0.51 10.8 8.3 0.52 10.8 8.3 1.1 1 0 0 1 1 1 0 AAA domain DivIC PF04977.15 KSA02969.1 - 0.64 9.8 8.8 0.76 9.6 8.0 1.6 1 1 0 1 1 1 0 Septum formation initiator Ribosomal_S18 PF01084.20 KSA02970.1 - 2.1e-20 72.7 0.0 5.7e-20 71.3 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein S18 Metallophos PF00149.28 KSA02971.1 - 5.8e-37 128.2 0.2 8.1e-37 127.7 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF5378 PF17349.2 KSA02971.1 - 0.039 13.3 0.0 0.057 12.7 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5378) STPPase_N PF16891.5 KSA02971.1 - 0.057 13.9 0.5 0.12 12.8 0.5 1.5 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Glyco_hydro_65N PF03636.15 KSA02971.1 - 0.1 12.2 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain RRM_1 PF00076.22 KSA02972.1 - 6.6e-53 176.4 0.6 1.2e-14 53.9 0.2 5.3 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CDC45 PF02724.14 KSA02972.1 - 7.5e-07 27.8 13.1 7.5e-07 27.8 13.1 2.4 2 0 0 2 2 2 1 CDC45-like protein RRM_7 PF16367.5 KSA02972.1 - 7e-06 26.1 0.0 0.068 13.3 0.0 3.8 3 0 0 3 3 3 2 RNA recognition motif RRM_Rrp7 PF17799.1 KSA02972.1 - 0.0003 20.6 0.6 2.1 8.2 0.1 3.6 3 0 0 3 3 3 2 Rrp7 RRM-like N-terminal domain Nop14 PF04147.12 KSA02972.1 - 2.3 6.3 55.1 0.0083 14.4 33.4 2.5 2 0 0 2 2 2 0 Nop14-like family CENP-N PF05238.13 KSA02973.1 - 1.4e-115 386.9 0.5 1.6e-115 386.7 0.5 1.0 1 0 0 1 1 1 1 Kinetochore protein CHL4 like Rap1_C PF11626.8 KSA02973.1 - 0.15 12.2 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Vps16_N PF04841.13 KSA02974.1 - 4.9e-47 160.6 1.0 2.4e-43 148.4 1.0 3.2 1 1 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.12 KSA02974.1 - 5.8e-45 153.7 12.2 6.3e-31 107.6 7.4 2.4 2 0 0 2 2 2 2 Vps16, C-terminal region DUF4127 PF13552.6 KSA02974.1 - 0.015 13.9 3.2 0.16 10.6 1.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4127) LEP503 PF15221.6 KSA02974.1 - 0.43 10.9 1.3 0.96 9.8 1.3 1.5 1 0 0 1 1 1 0 Lens epithelial cell protein LEP503 Skp1_POZ PF03931.15 KSA02975.1 - 0.00017 21.7 0.3 0.00052 20.1 0.3 1.8 1 1 0 1 1 1 1 Skp1 family, tetramerisation domain CLTH PF10607.9 KSA02976.1 - 1.8e-31 109.0 4.0 4.2e-31 107.8 4.0 1.7 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 KSA02976.1 - 0.0071 16.4 0.0 0.034 14.2 0.0 2.1 1 1 0 1 1 1 1 RING-type zinc-finger PyrI_C PF02748.15 KSA02976.1 - 0.025 14.5 1.3 0.054 13.4 0.4 2.1 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain AdoMet_MTase PF07757.13 KSA02977.1 - 6.6e-44 148.8 0.1 1.1e-43 148.1 0.1 1.3 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_32 PF13679.6 KSA02977.1 - 0.019 15.0 2.6 0.64 10.0 0.0 3.2 2 1 1 3 3 3 0 Methyltransferase domain Pkinase PF00069.25 KSA02978.1 - 1.4e-59 201.7 0.0 1.9e-59 201.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KSA02978.1 - 3.8e-26 91.9 0.0 5.7e-26 91.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KSA02978.1 - 0.022 13.7 0.1 0.044 12.7 0.1 1.5 1 0 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 KSA02978.1 - 0.024 13.7 0.1 0.041 12.9 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Kinase-like PF14531.6 KSA02978.1 - 0.03 13.6 0.3 0.058 12.7 0.3 1.7 1 1 0 1 1 1 0 Kinase-like APH PF01636.23 KSA02978.1 - 0.12 12.3 0.0 0.12 12.3 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family ICL PF00463.21 KSA02980.1 - 0 1025.1 1.7 0 1024.9 1.7 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 KSA02980.1 - 5e-12 45.8 0.0 1.3e-11 44.4 0.0 1.6 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase AEP1 PF17049.5 KSA02980.1 - 0.033 13.3 1.2 0.077 12.1 1.2 1.5 1 0 0 1 1 1 0 ATPase expression protein 1 PQ-loop PF04193.14 KSA02981.1 - 9.8e-11 41.3 8.1 5.7e-09 35.6 1.4 3.0 2 1 1 3 3 3 2 PQ loop repeat ER_lumen_recept PF00810.18 KSA02981.1 - 0.0013 19.5 1.3 0.0013 19.5 1.3 2.8 3 1 0 3 3 3 1 ER lumen protein retaining receptor zf-C2H2 PF00096.26 KSA02982.1 - 8.6e-07 29.1 0.6 0.0082 16.6 0.1 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KSA02982.1 - 0.0013 19.4 2.6 0.58 11.2 0.0 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-Di19 PF05605.12 KSA02982.1 - 0.039 14.3 0.0 0.1 12.9 0.0 1.8 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf_ZIC PF18366.1 KSA02982.1 - 0.047 13.8 0.0 0.15 12.2 0.0 1.8 2 0 0 2 2 2 0 Zic proteins zinc finger domain Zn_clus PF00172.18 KSA02983.1 - 6.2e-08 32.6 10.2 1.4e-07 31.5 10.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KSA02983.1 - 2e-05 23.8 1.2 2e-05 23.8 1.2 1.9 2 1 0 2 2 2 1 Fungal specific transcription factor domain DASH_Spc34 PF08657.10 KSA02983.1 - 0.0025 17.6 0.2 0.0047 16.8 0.2 1.3 1 0 0 1 1 1 1 DASH complex subunit Spc34 DASH_Spc19 PF08287.11 KSA02983.1 - 0.01 15.7 1.8 0.015 15.2 0.4 1.9 2 0 0 2 2 2 0 Spc19 Fmp27_WPPW PF10359.9 KSA02983.1 - 0.018 13.9 0.5 0.03 13.2 0.5 1.3 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Hydrolase_4 PF12146.8 KSA02984.1 - 0.00036 19.9 0.1 0.1 11.8 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KSA02984.1 - 0.0032 17.2 0.3 0.036 13.7 0.3 2.0 1 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KSA02984.1 - 0.081 13.5 0.0 0.096 13.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family HypF_C PF17788.1 KSA02984.1 - 0.16 12.7 0.0 0.54 11.0 0.0 1.8 2 0 0 2 2 2 0 HypF Kae1-like domain His_Phos_1 PF00300.22 KSA02985.1 - 7.6e-36 123.6 0.0 1e-26 93.8 0.0 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) DUF3605 PF12239.8 KSA02986.1 - 2.6e-50 170.7 4.0 3.2e-50 170.4 4.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) CENP-T_C PF15511.6 KSA02987.1 - 2.4e-09 37.3 0.1 2.9e-09 37.0 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 KSA02987.1 - 3e-05 24.1 0.1 4.2e-05 23.6 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KSA02987.1 - 5.3e-05 23.4 0.0 9.4e-05 22.6 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 KSA02987.1 - 7.4e-05 23.1 0.1 9.7e-05 22.7 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein Histone PF00125.24 KSA02987.1 - 0.0001 22.7 0.1 0.00012 22.4 0.1 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KSA02987.1 - 0.0043 17.1 0.0 0.0051 16.9 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KSA02987.1 - 0.009 16.0 0.0 0.01 15.8 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated UPF0137 PF03677.13 KSA02987.1 - 0.021 14.6 0.2 0.026 14.3 0.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) TFIID_20kDa PF03847.13 KSA02987.1 - 0.081 13.4 0.0 0.13 12.7 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A BDV_G PF06208.11 KSA02987.1 - 0.14 11.3 0.0 0.16 11.1 0.0 1.0 1 0 0 1 1 1 0 Borna disease virus G protein Histone PF00125.24 KSA02988.1 - 5.3e-51 172.4 2.8 5.9e-51 172.2 2.8 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KSA02988.1 - 3.8e-06 27.2 0.0 5.8e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KSA02988.1 - 5e-05 23.4 0.5 8e-05 22.7 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 KSA02988.1 - 5.6e-05 23.7 1.3 6.9e-05 23.5 1.3 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 KSA02988.1 - 0.0052 17.0 0.6 0.0079 16.5 0.1 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KSA02988.1 - 0.023 14.8 0.1 0.039 14.0 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Pkinase PF00069.25 KSA02989.1 - 4.5e-11 42.6 0.1 9.2e-11 41.6 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KSA02989.1 - 1.7e-05 24.9 0.0 3e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KSA02989.1 - 3.2e-05 23.3 0.0 7.2e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 KSA02989.1 - 0.0001 21.9 0.1 0.00025 20.7 0.1 1.6 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 KSA02989.1 - 0.0039 16.8 0.0 0.0085 15.7 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 KSA02989.1 - 0.017 14.5 0.0 0.03 13.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KSA02989.1 - 0.026 13.5 0.0 0.052 12.5 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 KSA02989.1 - 0.027 13.3 0.2 0.06 12.1 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase Mannosyl_trans2 PF04188.13 KSA02990.1 - 7.8e-39 134.2 19.4 1.7e-27 96.9 6.1 2.0 1 1 1 2 2 2 2 Mannosyltransferase (PIG-V) AMP-binding PF00501.28 KSA02991.1 - 1e-86 291.2 0.0 1.3e-86 290.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KSA02991.1 - 1.8e-24 86.5 1.1 9e-24 84.3 0.7 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 KSA02991.1 - 5.3e-19 67.9 0.1 1.5e-18 66.4 0.1 1.9 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus PUA PF01472.20 KSA02991.1 - 0.0019 18.1 0.9 0.021 14.7 0.6 2.4 2 0 0 2 2 2 1 PUA domain SEFIR PF08357.11 KSA02991.1 - 0.084 13.1 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 SEFIR domain Pkinase PF00069.25 KSA02992.1 - 1.4e-11 44.3 0.2 1.9e-11 43.8 0.2 1.2 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 KSA02992.1 - 1.8e-06 28.1 0.0 2.3e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KSA02992.1 - 3.3e-06 26.6 0.1 4.7e-06 26.1 0.1 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 KSA02992.1 - 9.9e-06 25.3 0.2 1.1e-05 25.1 0.2 1.2 1 1 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 KSA02992.1 - 0.00062 19.4 0.0 0.0008 19.1 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 KSA02992.1 - 0.00068 19.0 0.0 0.00084 18.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KSA02992.1 - 0.0041 16.1 0.0 0.0057 15.6 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KSA02992.1 - 0.0049 15.7 0.0 0.006 15.4 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 KSA02992.1 - 0.026 14.2 0.0 0.027 14.1 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Seadorna_VP7 PF07387.11 KSA02992.1 - 0.029 13.4 0.0 0.035 13.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 WaaY PF06176.11 KSA02992.1 - 0.033 13.8 0.1 0.042 13.5 0.1 1.1 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Kinase-like PF14531.6 KSA02992.1 - 0.1 11.9 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Kinase-like HSP70 PF00012.20 KSA02993.1 - 8.9e-260 863.0 9.5 1e-259 862.8 9.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KSA02993.1 - 5.8e-18 64.8 0.0 8.4e-17 61.0 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 KSA02993.1 - 0.00053 19.8 0.0 0.0068 16.2 0.0 2.3 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 KSA02993.1 - 0.024 13.9 0.1 0.07 12.4 0.1 1.8 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase DUF1464 PF07318.12 KSA02993.1 - 0.027 13.7 0.1 0.38 9.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1464) UPF0242 PF06785.11 KSA02993.1 - 0.91 9.6 11.2 0.099 12.7 6.7 1.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Golgin_A5 PF09787.9 KSA02993.1 - 6.5 6.1 10.5 3.9 6.8 6.4 2.0 2 0 0 2 2 2 0 Golgin subfamily A member 5 UPF0121 PF03661.13 KSA02994.1 - 2.4e-30 105.7 7.5 2.9e-30 105.4 7.5 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) MGC-24 PF05283.11 KSA02994.1 - 0.17 12.3 1.9 0.27 11.7 1.9 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Septin PF00735.18 KSA02995.1 - 3.5e-111 371.0 1.2 3.5e-111 371.0 1.2 1.5 2 0 0 2 2 2 1 Septin RsgA_GTPase PF03193.16 KSA02995.1 - 1.3e-05 25.1 2.8 0.011 15.6 0.0 2.8 3 0 0 3 3 3 2 RsgA GTPase AAA_16 PF13191.6 KSA02995.1 - 0.012 16.0 0.2 0.2 12.0 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain MMR_HSR1 PF01926.23 KSA02995.1 - 0.017 15.2 1.2 0.025 14.6 0.0 2.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase Strep_SA_rep PF06696.11 KSA02995.1 - 0.026 14.5 0.7 0.026 14.5 0.7 2.3 2 0 0 2 2 2 0 Streptococcal surface antigen repeat AAA_24 PF13479.6 KSA02995.1 - 0.061 13.1 0.7 0.19 11.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain FAM76 PF16046.5 KSA02995.1 - 0.33 10.3 8.7 0.53 9.6 8.7 1.3 1 0 0 1 1 1 0 FAM76 protein IIGP PF05049.13 KSA02995.1 - 0.42 9.6 0.1 0.42 9.6 0.1 2.3 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) DUF4776 PF16003.5 KSA02995.1 - 0.57 9.1 9.7 0.85 8.6 9.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) Exonuc_VII_L PF02601.15 KSA02995.1 - 2.2 7.8 10.2 4.2 6.9 10.2 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit ABC_tran PF00005.27 KSA02995.1 - 3.5 8.2 0.0 3.5 8.2 0.0 3.1 3 1 0 3 3 3 0 ABC transporter Dynamin_N PF00350.23 KSA02995.1 - 6.1 6.9 6.3 1.5 8.8 0.0 2.7 2 2 0 2 2 2 0 Dynamin family YlbE PF14003.6 KSA02995.1 - 7.6 7.1 8.3 2.1 8.9 0.9 3.1 2 1 1 3 3 3 0 YlbE-like protein CinA PF02464.17 KSA02996.1 - 9.9e-32 109.6 0.0 1.3e-31 109.3 0.0 1.1 1 0 0 1 1 1 1 Competence-damaged protein HlyD_D4 PF16572.5 KSA02996.1 - 0.032 14.1 0.0 0.09 12.7 0.0 1.7 1 0 0 1 1 1 0 Long alpha hairpin domain of cation efflux system protein, CusB Proteasom_Rpn13 PF04683.13 KSA02997.1 - 1.6e-24 86.2 0.0 2.4e-24 85.7 0.0 1.2 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor RPN13_C PF16550.5 KSA02998.1 - 3.2e-09 36.9 0.5 7.7e-09 35.7 0.1 1.7 1 1 1 2 2 2 1 UCH-binding domain Peptidase_S11 PF00768.20 KSA02998.1 - 0.098 12.1 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase Pkinase PF00069.25 KSA02999.1 - 2.9e-49 167.8 2.9 4e-20 72.3 0.0 3.5 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KSA02999.1 - 7.9e-25 87.6 0.7 2e-22 79.7 0.7 3.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KSA02999.1 - 0.04 13.2 0.1 2.6 7.3 0.1 2.6 1 1 0 1 1 1 0 Kinase-like VWA_2 PF13519.6 KSA02999.1 - 0.093 13.4 0.1 0.33 11.6 0.0 2.0 2 0 0 2 2 2 0 von Willebrand factor type A domain DUF3543 PF12063.8 KSA03000.1 - 4.5e-87 291.6 2.1 1e-86 290.4 2.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.25 KSA03000.1 - 8.2e-64 215.5 0.0 1.6e-63 214.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KSA03000.1 - 1.8e-42 145.4 0.0 2.9e-42 144.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KSA03000.1 - 1.3e-06 28.0 0.1 0.00016 21.1 0.0 3.4 3 1 0 3 3 3 1 Kinase-like Pkinase_fungal PF17667.1 KSA03000.1 - 0.034 12.9 0.0 0.066 12.0 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase MIT PF04212.18 KSA03000.1 - 0.13 12.3 0.5 12 6.1 0.1 2.8 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain KicB PF03882.14 KSA03000.1 - 3.6 7.8 5.3 0.56 10.4 0.9 1.9 2 0 0 2 2 2 0 MukF winged-helix domain SHR-BD PF06650.12 KSA03001.1 - 2.6e-94 315.6 15.6 9.5e-93 310.5 5.4 4.0 3 1 1 4 4 4 2 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13_mid_rpt PF16910.5 KSA03001.1 - 4.7e-88 294.6 9.5 1.3e-84 283.3 1.7 4.9 3 1 1 4 4 4 2 Repeating coiled region of VPS13 VPS13 PF16908.5 KSA03001.1 - 8.4e-81 271.2 15.2 4.5e-77 259.0 4.5 4.3 4 1 0 4 4 4 3 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 KSA03001.1 - 4.5e-72 241.6 6.2 7.3e-66 221.3 0.6 2.9 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal Chorein_N PF12624.7 KSA03001.1 - 8.2e-40 135.5 1.1 8.2e-40 135.5 1.1 3.6 4 0 0 4 4 4 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 KSA03001.1 - 5.1e-06 26.8 0.0 1.5e-05 25.3 0.0 1.8 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain NOA36 PF06524.12 KSA03001.1 - 2.7 7.2 3.9 5.3 6.3 3.9 1.4 1 0 0 1 1 1 0 NOA36 protein DUF4637 PF15470.6 KSA03001.1 - 2.9 7.6 8.4 7.6 6.2 8.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) DUF4611 PF15387.6 KSA03001.1 - 4.6 7.5 9.0 2.1 8.6 3.0 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Formyl_trans_N PF00551.19 KSA03002.1 - 2.1e-31 109.1 0.0 2.7e-31 108.7 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 KSA03002.1 - 3.7e-05 23.9 0.0 6.9e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain Nodulin-like PF06813.13 KSA03003.1 - 3.7e-15 56.1 4.5 3.7e-15 56.1 4.5 2.7 3 1 0 3 3 3 1 Nodulin-like MFS_1 PF07690.16 KSA03003.1 - 3.9e-12 45.8 23.2 3.9e-12 45.8 23.2 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily Trp_syntA PF00290.20 KSA03006.1 - 9.1e-94 313.1 0.3 1.4e-93 312.5 0.3 1.2 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.25 KSA03006.1 - 6.5e-46 157.1 1.3 9.6e-46 156.5 1.3 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme MOZART1 PF12554.8 KSA03007.1 - 1.6e-15 56.6 1.6 2e-15 56.3 1.6 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated Rrn6 PF10214.9 KSA03008.1 - 2.4e-135 453.1 30.0 7.8e-135 451.5 30.0 1.8 1 1 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor Glyco_hydro_63 PF03200.16 KSA03009.1 - 6.6e-194 645.2 5.3 5.6e-193 642.2 5.3 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 KSA03009.1 - 1.1e-75 254.7 0.5 2.7e-75 253.4 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 63 N-terminal domain Trehalase PF01204.18 KSA03009.1 - 0.00049 19.0 0.8 0.00085 18.3 0.8 1.3 1 0 0 1 1 1 1 Trehalase MCM_lid PF17855.1 KSA03009.1 - 0.027 14.9 0.1 0.087 13.2 0.1 1.8 1 0 0 1 1 1 0 MCM AAA-lid domain Oxidored_FMN PF00724.20 KSA03010.1 - 7.1e-92 308.3 0.0 8.6e-92 308.0 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family TBPIP PF07106.13 KSA03011.1 - 2.5e-20 72.1 1.8 2.5e-20 72.1 1.8 1.9 2 0 0 2 2 2 1 TBPIP/Hop2 winged helix domain Spc7 PF08317.11 KSA03011.1 - 0.0058 15.5 11.4 0.0072 15.2 11.4 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein Imm25 PF15564.6 KSA03011.1 - 0.0063 16.4 0.1 0.0082 16.1 0.1 1.3 1 0 0 1 1 1 1 Immunity protein 25 FlxA PF14282.6 KSA03011.1 - 0.007 16.3 5.6 0.013 15.4 5.6 1.5 1 0 0 1 1 1 1 FlxA-like protein Mito_fiss_reg PF05308.11 KSA03011.1 - 0.023 14.8 1.8 0.03 14.4 1.8 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator Cep57_MT_bd PF06657.13 KSA03011.1 - 0.039 14.4 6.0 0.045 14.2 4.5 1.9 1 1 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 DUF3793 PF12672.7 KSA03011.1 - 0.039 14.0 0.4 0.039 14.0 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3793) FlaC_arch PF05377.11 KSA03011.1 - 0.063 13.7 13.9 2.6 8.5 1.6 3.5 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) LPP PF04728.13 KSA03011.1 - 0.11 12.9 1.8 0.67 10.4 0.1 2.5 2 0 0 2 2 2 0 Lipoprotein leucine-zipper ADIP PF11559.8 KSA03011.1 - 0.15 12.2 11.1 0.039 14.1 7.9 1.7 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Allexi_40kDa PF05549.11 KSA03011.1 - 0.17 11.4 5.1 0.084 12.4 1.8 1.7 1 1 1 2 2 2 0 Allexivirus 40kDa protein DUF4349 PF14257.6 KSA03011.1 - 0.19 11.2 2.5 0.32 10.4 2.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) Baculo_PEP_C PF04513.12 KSA03011.1 - 0.3 11.1 3.3 0.27 11.3 0.9 1.8 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF501 PF04417.12 KSA03011.1 - 0.42 10.4 3.0 1.7 8.5 1.3 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF501) DBINO PF13892.6 KSA03011.1 - 0.48 10.8 9.9 0.71 10.2 9.2 1.6 1 1 0 1 1 1 0 DNA-binding domain NPV_P10 PF05531.12 KSA03011.1 - 0.53 10.8 5.1 0.26 11.8 2.2 1.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DivIC PF04977.15 KSA03011.1 - 0.59 9.9 13.0 0.46 10.3 1.7 2.7 1 1 1 2 2 2 0 Septum formation initiator Swi5 PF07061.11 KSA03011.1 - 1 9.5 9.7 2.1e+02 2.1 9.7 2.6 1 1 0 1 1 1 0 Swi5 Bcr-Abl_Oligo PF09036.10 KSA03011.1 - 1.5 8.8 5.1 16 5.6 0.2 2.7 2 1 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain DUF1664 PF07889.12 KSA03011.1 - 2.5 8.2 6.2 6.1 6.9 4.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF5344 PF17279.2 KSA03011.1 - 4.5 7.9 12.2 4 8.1 5.7 3.0 2 1 1 3 3 3 0 Family of unknown function (DUF5344) ZapB PF06005.12 KSA03011.1 - 5.7 7.4 13.4 59 4.2 13.4 2.5 1 1 0 1 1 1 0 Cell division protein ZapB Laminin_II PF06009.12 KSA03011.1 - 6.4 6.8 12.7 1.6 8.7 8.4 2.2 2 1 0 2 2 2 0 Laminin Domain II CLTH PF10607.9 KSA03012.1 - 4.4e-32 111.0 8.3 4.4e-32 111.0 8.3 2.7 3 0 0 3 3 3 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 KSA03012.1 - 3.6e-07 29.9 1.6 4e-07 29.8 0.2 1.9 2 0 0 2 2 2 1 LisH LIP PF03583.14 KSA03014.1 - 5.1e-103 344.3 0.1 6.5e-103 344.0 0.1 1.1 1 0 0 1 1 1 1 Secretory lipase Peptidase_S9 PF00326.21 KSA03014.1 - 0.00053 19.5 0.0 0.029 13.9 0.0 2.3 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KSA03014.1 - 0.039 13.6 0.0 4.8 6.7 0.0 2.3 2 0 0 2 2 2 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KSA03014.1 - 0.093 12.0 0.0 0.24 10.6 0.0 1.6 2 0 0 2 2 2 0 Serine aminopeptidase, S33 LIP PF03583.14 KSA03015.1 - 3.1e-102 341.7 0.3 3.9e-102 341.4 0.3 1.1 1 0 0 1 1 1 1 Secretory lipase Peptidase_S9 PF00326.21 KSA03015.1 - 6.5e-06 25.8 0.6 0.08 12.4 0.0 2.5 2 1 1 3 3 3 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KSA03015.1 - 0.055 12.7 0.2 1.4 8.1 0.0 2.4 2 1 1 3 3 3 0 Serine aminopeptidase, S33 ssDBP_DBD PF18361.1 KSA03015.1 - 0.13 12.4 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Single stranded DNA-binding protein ss DNA binding domain DUF4898 PF16239.5 KSA03016.1 - 0.1 12.5 1.8 0.24 11.4 1.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4898) AA_permease_2 PF13520.6 KSA03017.1 - 7.2e-72 242.5 37.1 9.2e-72 242.2 37.1 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KSA03017.1 - 1.1e-10 40.7 33.9 1.6e-10 40.2 33.9 1.2 1 0 0 1 1 1 1 Amino acid permease ABC_tran PF00005.27 KSA03018.1 - 2e-56 190.3 0.2 5.5e-33 114.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KSA03018.1 - 2.8e-52 178.1 39.7 1e-32 113.9 15.9 3.5 3 1 0 3 3 3 2 ABC transporter transmembrane region AAA_23 PF13476.6 KSA03018.1 - 1.1e-08 35.9 11.8 4.2e-05 24.1 0.1 3.6 4 0 0 4 4 3 2 AAA domain AAA_29 PF13555.6 KSA03018.1 - 6.7e-08 32.2 0.1 0.0015 18.2 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 KSA03018.1 - 2.9e-07 30.1 7.0 0.018 14.5 3.1 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KSA03018.1 - 1.1e-06 28.7 1.8 0.0049 16.7 0.1 3.4 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KSA03018.1 - 1.5e-05 25.0 0.0 0.027 14.4 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 KSA03018.1 - 7.4e-05 23.0 0.4 1.1 9.6 0.1 3.1 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KSA03018.1 - 0.0001 22.7 0.1 0.3 11.5 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 KSA03018.1 - 0.00012 22.2 0.1 0.084 13.0 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_24 PF13479.6 KSA03018.1 - 0.00038 20.2 0.3 0.032 13.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KSA03018.1 - 0.0021 17.6 0.1 0.74 9.3 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region T2SSE PF00437.20 KSA03018.1 - 0.0034 16.5 0.0 0.13 11.3 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein Dynamin_N PF00350.23 KSA03018.1 - 0.0075 16.3 0.5 0.97 9.5 0.0 3.2 3 0 0 3 3 3 1 Dynamin family AAA_15 PF13175.6 KSA03018.1 - 0.017 14.8 0.1 0.017 14.8 0.1 4.1 4 1 0 4 4 3 0 AAA ATPase domain Zeta_toxin PF06414.12 KSA03018.1 - 0.026 13.8 0.0 3.5 6.8 0.0 2.6 3 0 0 3 3 3 0 Zeta toxin AAA_25 PF13481.6 KSA03018.1 - 0.032 13.8 0.0 0.43 10.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KSA03018.1 - 0.034 13.9 0.1 12 5.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KSA03018.1 - 0.036 14.5 0.3 5.8 7.3 0.0 3.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Roc PF08477.13 KSA03018.1 - 0.04 14.2 0.4 12 6.1 0.1 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase FtsK_SpoIIIE PF01580.18 KSA03018.1 - 0.048 13.0 0.0 4.2 6.7 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_27 PF13514.6 KSA03018.1 - 0.11 12.1 0.0 5.6 6.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 KSA03018.1 - 0.31 10.6 2.2 2.1 7.9 0.4 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.17 KSA03018.1 - 0.42 10.4 1.7 38 3.9 0.1 3.4 3 1 1 4 4 4 0 Conserved hypothetical ATP binding protein DUF87 PF01935.17 KSA03018.1 - 5.1 7.1 8.8 1.4 9.0 0.0 3.3 4 0 0 4 4 3 0 Helicase HerA, central domain Ribosomal_L2_C PF03947.18 KSA03019.1 - 1.3e-42 145.0 4.3 2.3e-42 144.2 4.3 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 KSA03019.1 - 1.8e-14 53.5 0.1 4.3e-14 52.2 0.1 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain RRM_1 PF00076.22 KSA03020.1 - 5.3e-20 71.0 4.4 2.5e-09 36.8 0.2 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KSA03020.1 - 0.0057 16.5 0.1 0.26 11.2 0.0 2.5 2 0 0 2 2 2 1 Occluded RNA-recognition motif DbpA PF03880.15 KSA03020.1 - 0.0063 16.5 0.4 0.69 10.0 0.1 2.9 2 0 0 2 2 2 1 DbpA RNA binding domain GREB1 PF15782.5 KSA03020.1 - 0.047 10.8 4.1 0.055 10.6 4.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer BRAP2 PF07576.12 KSA03020.1 - 0.08 13.2 0.9 0.81 10.0 0.2 2.2 2 0 0 2 2 2 0 BRCA1-associated protein 2 Limkain-b1 PF11608.8 KSA03020.1 - 0.088 12.9 0.7 17 5.5 0.0 2.6 2 0 0 2 2 2 0 Limkain b1 Pet100 PF09803.9 KSA03020.1 - 0.22 12.1 3.2 0.93 10.1 3.2 2.1 1 0 0 1 1 1 0 Pet100 SLC12 PF03522.15 KSA03020.1 - 0.75 8.8 8.3 1.1 8.1 8.3 1.3 1 0 0 1 1 1 0 Solute carrier family 12 MCM_bind PF09739.9 KSA03020.1 - 0.77 8.1 7.3 1 7.8 7.3 1.2 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Presenilin PF01080.17 KSA03020.1 - 5.5 5.6 9.2 9.4 4.9 9.2 1.3 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.10 KSA03020.1 - 5.9 5.5 5.7 6.9 5.2 5.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup UCR_hinge PF02320.16 KSA03021.1 - 1.1e-26 92.8 10.7 2e-26 91.9 10.7 1.4 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein Nop14 PF04147.12 KSA03021.1 - 0.016 13.5 28.1 0.018 13.3 28.1 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 KSA03021.1 - 0.068 11.4 16.9 0.077 11.3 16.9 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF913 PF06025.12 KSA03021.1 - 0.086 11.8 6.8 0.1 11.5 6.8 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) BUD22 PF09073.10 KSA03021.1 - 0.18 11.1 26.2 0.23 10.8 26.2 1.1 1 0 0 1 1 1 0 BUD22 SpoIIIAH PF12685.7 KSA03021.1 - 0.22 11.3 12.6 0.26 11.1 12.6 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein Mpp10 PF04006.12 KSA03021.1 - 0.53 8.7 27.0 0.74 8.2 27.0 1.2 1 0 0 1 1 1 0 Mpp10 protein Nop53 PF07767.11 KSA03021.1 - 0.7 9.2 21.4 0.85 8.9 21.4 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) NOA36 PF06524.12 KSA03021.1 - 0.72 9.1 26.4 1.5 8.1 26.4 1.5 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 KSA03021.1 - 0.94 7.5 38.3 1.2 7.2 38.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi SDA1 PF05285.12 KSA03021.1 - 1 8.7 31.2 1.3 8.4 31.2 1.1 1 0 0 1 1 1 0 SDA1 CPSF100_C PF13299.6 KSA03021.1 - 1.1 9.4 7.7 1.9 8.6 7.7 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal SAPS PF04499.15 KSA03021.1 - 2 7.1 10.1 2.2 7.0 10.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RRN3 PF05327.11 KSA03021.1 - 2.5 6.6 18.9 2.9 6.3 18.9 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF2076 PF09849.9 KSA03021.1 - 2.5 8.1 11.1 3.4 7.6 11.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) CobT PF06213.12 KSA03021.1 - 2.9 7.2 28.7 4.4 6.6 28.7 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT NPR3 PF03666.13 KSA03021.1 - 2.9 6.6 10.2 3.2 6.4 10.2 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.17 KSA03021.1 - 4.6 5.9 9.2 5 5.8 9.2 1.1 1 0 0 1 1 1 0 Presenilin Tau95 PF09734.9 KSA03022.1 - 6.5e-38 130.7 1.6 6.5e-38 130.7 1.6 3.1 3 0 0 3 3 3 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 KSA03022.1 - 2e-28 99.1 0.5 4.3e-28 98.0 0.5 1.6 1 0 0 1 1 1 1 Tau95 Triple barrel domain DPM3 PF08285.11 KSA03023.1 - 1.8e-33 114.6 0.0 2e-33 114.5 0.0 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF4381 PF14316.6 KSA03023.1 - 0.069 13.4 0.0 0.1 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Oxidored-like PF09791.9 KSA03024.1 - 2.7e-25 87.7 0.8 2.7e-25 87.7 0.8 1.9 2 0 0 2 2 2 1 Oxidoreductase-like protein, N-terminal Sulfate_transp PF00916.20 KSA03025.1 - 1.3e-68 231.5 23.1 1.9e-68 230.9 23.1 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KSA03025.1 - 4.3e-18 65.1 0.2 8.9e-18 64.0 0.2 1.5 1 0 0 1 1 1 1 STAS domain F_actin_cap_B PF01115.17 KSA03026.1 - 2.1e-93 312.4 0.4 2.4e-93 312.1 0.4 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit TDA11 PF17084.5 KSA03027.1 - 2.1e-09 36.9 33.1 2.2e-09 36.8 25.7 2.4 2 1 0 2 2 2 1 Topoisomerase I damage affected protein 11 Pkinase_fungal PF17667.1 KSA03027.1 - 0.51 9.0 7.0 0.049 12.4 2.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase CCDC-167 PF15188.6 KSA03027.1 - 1.2 9.6 7.0 0.17 12.2 2.1 2.2 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 DUF1746 PF08508.10 KSA03028.1 - 0.016 15.5 0.4 0.52 10.7 0.0 2.7 2 0 0 2 2 2 0 Fungal domain of unknown function (DUF1746) Clathrin_lg_ch PF01086.17 KSA03029.1 - 1.1e-58 199.0 19.5 1.3e-58 198.8 19.5 1.0 1 0 0 1 1 1 1 Clathrin light chain V-ATPase_G PF03179.15 KSA03029.1 - 1 9.9 14.2 1.1 9.8 6.6 2.3 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit DUF349 PF03993.12 KSA03029.1 - 7.8 6.9 15.3 3.2 8.1 1.7 3.7 2 1 1 3 3 3 0 Domain of Unknown Function (DUF349) WD40 PF00400.32 KSA03030.1 - 1.5e-42 142.7 9.8 3.1e-06 27.8 0.0 10.4 10 0 0 10 10 10 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KSA03030.1 - 6.3e-13 48.8 6.3 0.049 13.9 0.0 8.6 5 2 5 10 10 10 5 Anaphase-promoting complex subunit 4 WD40 domain BBS2_N PF14781.6 KSA03030.1 - 0.15 11.9 0.2 38 4.3 0.0 3.5 3 1 0 3 3 3 0 Ciliary BBSome complex subunit 2, N-terminal Med20 PF08612.11 KSA03031.1 - 5.1e-32 111.1 0.0 5.6e-32 110.9 0.0 1.0 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex DEAD PF00270.29 KSA03032.1 - 8.2e-47 159.2 0.1 1.7e-46 158.2 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KSA03032.1 - 2.9e-21 75.9 0.0 1.2e-20 73.9 0.0 2.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KSA03032.1 - 2.4e-19 69.3 0.0 7.8e-19 67.7 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KSA03032.1 - 1.8e-06 28.0 0.0 1.8e-06 28.0 0.0 2.7 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.6 KSA03032.1 - 0.0042 17.3 0.0 0.012 15.7 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain PSP PF04046.16 KSA03032.1 - 0.19 11.6 0.0 0.4 10.6 0.0 1.5 1 0 0 1 1 1 0 PSP RNA_pol_Rpc4 PF05132.14 KSA03033.1 - 2.8e-15 57.1 0.1 2.8e-15 57.1 0.1 4.2 3 2 1 4 4 4 2 RNA polymerase III RPC4 DUF3530 PF12048.8 KSA03033.1 - 1.9 7.8 5.5 0.14 11.5 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3530) RLL PF10036.9 KSA03033.1 - 4.9 6.9 8.9 0.61 9.9 4.2 1.8 2 1 0 2 2 2 0 RNA transcription, translation and transport factor protein Sas10 PF09368.10 KSA03034.1 - 3.4e-29 101.1 11.1 3.4e-29 101.1 11.1 2.6 3 0 0 3 3 3 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 KSA03034.1 - 2.7e-05 24.7 0.4 2.7e-05 24.7 0.4 3.0 3 0 0 3 3 3 1 Sas10/Utp3/C1D family Cyclin_C_2 PF16899.5 KSA03035.1 - 1.2e-28 99.5 1.0 3.4e-26 91.6 0.2 2.7 2 1 0 2 2 2 2 Cyclin C-terminal domain Cyclin_N PF00134.23 KSA03035.1 - 8.6e-13 48.1 0.8 2.2e-12 46.8 0.8 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.19 KSA03035.1 - 0.039 14.0 0.0 0.11 12.6 0.0 1.8 1 0 0 1 1 1 0 Transcription factor TFIIB repeat DUF5340 PF17275.2 KSA03035.1 - 0.079 13.1 0.4 0.18 12.0 0.4 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5340) Cpn60_TCP1 PF00118.24 KSA03036.1 - 1.3e-149 499.1 15.6 1.4e-149 498.9 15.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family D123 PF07065.14 KSA03037.1 - 6.6e-108 360.5 6.1 7.6e-108 360.3 6.1 1.0 1 0 0 1 1 1 1 D123 SGL PF08450.12 KSA03038.1 - 1.5e-68 231.1 0.1 1.7e-68 230.8 0.1 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 KSA03038.1 - 3.7e-05 23.8 0.1 0.00056 20.0 0.0 3.0 4 0 0 4 4 4 1 Strictosidine synthase Arylesterase PF01731.20 KSA03038.1 - 0.0023 18.1 0.0 0.025 14.8 0.0 2.5 3 0 0 3 3 3 1 Arylesterase NHL PF01436.21 KSA03038.1 - 0.034 14.2 0.3 8.9 6.6 0.0 4.4 5 0 0 5 5 5 0 NHL repeat WH1 PF00568.23 KSA03038.1 - 0.079 12.9 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 WH1 domain zf-HIT PF04438.16 KSA03039.1 - 7.6e-10 38.5 10.5 1e-09 38.1 10.5 1.2 1 0 0 1 1 1 1 HIT zinc finger Hit1_C PF18268.1 KSA03039.1 - 1.2e-08 35.0 0.1 2.2e-08 34.2 0.1 1.5 2 0 0 2 2 2 1 Hit1 C-terminal zf-MYND PF01753.18 KSA03039.1 - 0.038 14.1 7.1 0.056 13.5 7.1 1.2 1 0 0 1 1 1 0 MYND finger Baculo_p33 PF05214.12 KSA03039.1 - 0.069 12.9 0.3 0.083 12.6 0.3 1.2 1 0 0 1 1 1 0 Baculovirus P33 zf-C6H2 PF15801.5 KSA03039.1 - 0.17 12.2 5.5 0.28 11.5 5.5 1.4 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Cyclin_N PF00134.23 KSA03040.1 - 8.6e-05 22.3 1.3 0.00013 21.7 1.3 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 KSA03040.1 - 0.28 11.6 7.4 0.034 14.5 3.3 1.6 2 0 0 2 2 2 0 Cyclin zf-C2H2_7 PF15269.6 KSA03040.1 - 1.6 8.9 7.5 12 6.0 1.3 4.1 3 2 0 4 4 4 0 Zinc-finger Frag1 PF10277.9 KSA03041.1 - 1.9e-48 164.9 13.4 2.2e-48 164.7 13.4 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family MFS_1 PF07690.16 KSA03041.1 - 0.0064 15.5 4.9 0.0064 15.5 4.9 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Polysacc_synt_C PF14667.6 KSA03041.1 - 0.027 14.5 2.3 0.027 14.5 2.3 2.2 2 0 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain GWT1 PF06423.12 KSA03041.1 - 0.31 11.2 4.6 1.1 9.4 4.6 1.9 1 1 0 1 1 1 0 GWT1 DUF4818 PF16089.5 KSA03041.1 - 3.1 8.3 6.8 15 6.1 0.3 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4818) YibE_F PF07907.11 KSA03041.1 - 8.2 5.8 12.9 0.94 8.9 5.1 2.0 2 0 0 2 2 2 0 YibE/F-like protein Fungal_trans PF04082.18 KSA03042.1 - 5.8e-17 61.6 5.5 1.2e-16 60.5 5.5 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KSA03042.1 - 1.2e-07 31.7 13.1 2.2e-07 30.9 13.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.26 KSA03043.1 - 9.4e-11 41.6 15.0 3.3e-05 24.1 5.5 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KSA03043.1 - 3.7e-08 33.4 19.8 5.2e-06 26.6 5.0 3.6 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KSA03043.1 - 3.2e-06 27.5 11.6 0.0064 17.2 3.6 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KSA03043.1 - 0.064 13.6 0.5 0.064 13.6 0.5 3.5 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KSA03043.1 - 0.08 13.0 4.8 0.28 11.3 2.1 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger FOXP-CC PF16159.5 KSA03043.1 - 0.099 13.3 0.1 0.099 13.3 0.1 3.5 2 1 1 3 3 3 0 FOXP coiled-coil domain zf-C2HE PF16278.5 KSA03043.1 - 0.22 12.0 4.8 0.076 13.5 1.4 2.1 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-H2C2_5 PF13909.6 KSA03043.1 - 0.22 11.3 13.3 1.2 9.0 0.3 3.6 2 1 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2_8 PF15909.5 KSA03043.1 - 0.53 10.6 0.1 0.53 10.6 0.1 3.7 3 1 0 4 4 4 0 C2H2-type zinc ribbon Cyclin_N PF00134.23 KSA03044.1 - 0.00027 20.7 0.0 0.00041 20.1 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain CHZ PF09649.10 KSA03045.1 - 1.6e-19 69.1 0.5 1.6e-19 69.1 0.5 2.3 2 0 0 2 2 2 1 Histone chaperone domain CHZ LSM PF01423.22 KSA03046.1 - 3.2e-17 62.0 0.6 4.3e-17 61.6 0.6 1.2 1 0 0 1 1 1 1 LSM domain Ras PF00071.22 KSA03047.1 - 2.4e-59 199.6 0.1 2.8e-59 199.3 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KSA03047.1 - 2.2e-34 118.2 0.0 3.2e-34 117.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KSA03047.1 - 3.3e-12 46.2 0.0 4.2e-12 45.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KSA03047.1 - 4.2e-07 30.1 0.0 6.6e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase KAP_NTPase PF07693.14 KSA03047.1 - 0.00094 18.5 0.0 0.0019 17.5 0.0 1.4 1 1 0 1 1 1 1 KAP family P-loop domain RsgA_GTPase PF03193.16 KSA03047.1 - 0.0028 17.6 0.4 0.026 14.4 0.1 2.1 1 1 1 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 KSA03047.1 - 0.0041 16.7 0.0 0.012 15.1 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 KSA03047.1 - 0.0064 16.9 0.1 0.011 16.1 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 KSA03047.1 - 0.014 15.2 0.0 0.037 13.7 0.0 1.9 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KSA03047.1 - 0.016 15.7 0.0 0.032 14.8 0.0 1.6 1 1 0 1 1 1 0 ABC transporter Gtr1_RagA PF04670.12 KSA03047.1 - 0.017 14.5 0.0 0.024 14.0 0.0 1.3 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 KSA03047.1 - 0.019 15.2 0.1 0.067 13.5 0.0 1.9 1 1 1 2 2 2 0 AAA domain SRPRB PF09439.10 KSA03047.1 - 0.042 13.3 0.0 0.064 12.7 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_21 PF13304.6 KSA03047.1 - 0.054 13.3 0.2 0.23 11.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system PduV-EutP PF10662.9 KSA03047.1 - 0.061 13.1 0.0 0.17 11.6 0.0 1.6 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation TniB PF05621.11 KSA03047.1 - 0.11 11.9 0.0 0.24 10.8 0.0 1.5 2 0 0 2 2 2 0 Bacterial TniB protein NTPase_1 PF03266.15 KSA03047.1 - 0.11 12.4 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 NTPase FeoB_N PF02421.18 KSA03047.1 - 0.13 11.8 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B MCM PF00493.23 KSA03047.1 - 0.14 11.2 0.0 0.39 9.8 0.0 1.7 2 1 0 2 2 2 0 MCM P-loop domain SPT16 PF08644.11 KSA03048.1 - 1.8e-49 167.8 0.1 1.8e-49 167.8 0.1 2.8 3 0 0 3 3 3 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.6 KSA03048.1 - 1.7e-47 161.2 1.4 1.7e-47 161.2 1.4 2.9 3 0 0 3 3 3 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 KSA03048.1 - 6.8e-25 88.0 0.0 1.3e-24 87.1 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 KSA03048.1 - 8.1e-14 51.8 0.0 2.3e-13 50.4 0.0 1.8 1 0 0 1 1 1 1 Histone chaperone Rttp106-like DNA_primase_lrg PF04104.14 KSA03049.1 - 6.4e-84 281.5 0.0 9.8e-84 280.9 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Xan_ur_permease PF00860.20 KSA03051.1 - 4e-73 246.4 33.8 5.7e-73 245.9 33.8 1.1 1 0 0 1 1 1 1 Permease family Borrelia_P83 PF05262.11 KSA03052.1 - 3.2e-05 22.6 36.5 4.5e-05 22.1 36.5 1.3 1 0 0 1 1 1 1 Borrelia P83/100 protein LicD PF04991.13 KSA03053.1 - 1.1e-32 114.0 12.3 2.4e-25 90.0 1.3 3.1 2 1 1 3 3 3 3 LicD family HLH PF00010.26 KSA03054.1 - 4.1e-15 55.5 4.8 4.1e-15 55.5 4.8 2.2 3 0 0 3 3 3 1 Helix-loop-helix DNA-binding domain TFIIA PF03153.13 KSA03054.1 - 0.0038 17.3 31.7 0.0053 16.8 31.7 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit TPP_enzyme_N PF02776.18 KSA03055.1 - 4.3e-31 107.8 0.0 7.6e-31 107.0 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 KSA03055.1 - 1.3e-25 89.7 0.0 8.6e-25 87.1 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 KSA03055.1 - 4.1e-12 46.2 0.0 8.9e-12 45.0 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain ABC_membrane PF00664.23 KSA03056.1 - 1.5e-38 133.1 16.2 2e-38 132.6 16.2 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KSA03056.1 - 2.2e-35 122.2 0.3 4.7e-35 121.1 0.0 1.7 2 0 0 2 2 1 1 ABC transporter SMC_N PF02463.19 KSA03056.1 - 5.1e-11 42.4 0.1 1.3e-07 31.2 0.0 2.5 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KSA03056.1 - 3.4e-05 23.8 0.6 0.0045 16.8 0.1 2.3 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KSA03056.1 - 0.0011 18.7 0.1 0.003 17.3 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 KSA03056.1 - 0.002 17.9 0.0 0.0035 17.1 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KSA03056.1 - 0.0021 18.3 0.1 0.011 16.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KSA03056.1 - 0.0032 17.9 0.1 0.0074 16.7 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 KSA03056.1 - 0.0033 17.2 0.0 0.0056 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 KSA03056.1 - 0.024 14.7 0.1 0.071 13.2 0.0 1.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_30 PF13604.6 KSA03056.1 - 0.034 13.9 0.0 0.085 12.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KSA03056.1 - 0.061 13.8 5.9 0.72 10.3 5.9 2.4 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.7 KSA03056.1 - 0.072 12.0 0.1 0.46 9.4 0.0 2.0 2 1 0 2 2 2 0 AAA-like domain Cytidylate_kin PF02224.18 KSA03056.1 - 0.12 12.1 0.3 0.31 10.8 0.1 1.7 1 1 1 2 2 2 0 Cytidylate kinase AAA PF00004.29 KSA03056.1 - 0.12 12.8 0.1 0.93 9.9 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KSA03056.1 - 0.13 12.8 0.0 0.35 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KSA03056.1 - 0.14 11.7 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Peptidase_M1 PF01433.20 KSA03058.1 - 1.9e-47 161.6 1.2 5.1e-47 160.2 1.2 1.8 1 1 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 KSA03058.1 - 2.3e-37 129.2 0.5 3.5e-37 128.6 0.5 1.2 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 KSA03058.1 - 4.3e-20 72.7 3.2 6.6e-20 72.1 0.4 2.3 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain ORC5_C PF14630.6 KSA03058.1 - 0.012 15.2 0.0 0.025 14.1 0.0 1.5 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 5 C-terminus Fumble PF03630.14 KSA03059.1 - 1.1e-126 422.5 1.2 1.4e-126 422.1 1.2 1.1 1 0 0 1 1 1 1 Fumble PEX11 PF05648.14 KSA03060.1 - 2.6e-07 30.4 4.7 0.00044 19.8 3.5 2.8 2 1 0 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) CFIA_Pcf11 PF11526.8 KSA03060.1 - 5.2 7.6 16.2 4.2 7.9 3.0 2.6 2 0 0 2 2 2 0 Subunit of cleavage factor IA Pcf11 PALP PF00291.25 KSA03061.1 - 1.2e-65 221.8 0.0 1.4e-65 221.6 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Fungal_trans PF04082.18 KSA03062.1 - 4.2e-17 62.0 4.0 4.2e-17 62.0 4.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KSA03062.1 - 5.7e-10 39.2 9.6 9.5e-10 38.4 9.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KSA03063.1 - 6e-28 97.6 0.4 1.7e-27 96.1 0.0 2.0 1 1 1 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KSA03063.1 - 9.2e-10 38.5 9.7 1.5e-09 37.8 9.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain dDENN PF03455.19 KSA03063.1 - 0.16 12.0 0.9 3.5 7.7 0.1 2.6 2 0 0 2 2 2 0 dDENN domain DUF5102 PF17104.5 KSA03064.1 - 5.3e-32 112.0 10.7 5.3e-32 112.0 10.7 2.6 1 1 0 2 2 2 1 Domain of unknown function (DUF5102) Pept_tRNA_hydro PF01195.19 KSA03065.1 - 9.3e-27 94.1 0.0 1.1e-26 93.8 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase AAA PF00004.29 KSA03065.1 - 0.11 13.0 0.0 0.16 12.4 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF3336 PF11815.8 KSA03066.1 - 4.6e-46 156.0 1.6 4.6e-46 156.0 1.6 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.22 KSA03066.1 - 2.2e-14 54.1 0.1 1.2e-13 51.7 0.0 2.3 2 0 0 2 2 2 1 Patatin-like phospholipase IGPS PF00218.21 KSA03066.1 - 0.15 11.2 0.1 0.31 10.2 0.1 1.5 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase Hydrolase PF00702.26 KSA03067.1 - 0.089 13.1 0.0 0.52 10.6 0.0 2.0 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase 5-nucleotidase PF06189.12 KSA03067.1 - 0.12 11.2 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 5'-nucleotidase UBA PF00627.31 KSA03068.1 - 9.5e-25 86.1 9.1 2.8e-13 49.5 0.2 2.7 3 0 0 3 3 3 2 UBA/TS-N domain ubiquitin PF00240.23 KSA03068.1 - 7.8e-18 64.0 0.8 1.4e-17 63.2 0.8 1.4 1 0 0 1 1 1 1 Ubiquitin family XPC-binding PF09280.11 KSA03068.1 - 2.5e-17 62.4 2.3 5.2e-17 61.3 2.3 1.5 1 0 0 1 1 1 1 XPC-binding domain Rad60-SLD PF11976.8 KSA03068.1 - 7.7e-07 28.9 2.7 1.6e-06 27.8 2.7 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 KSA03068.1 - 0.00014 21.9 0.1 0.00028 21.0 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 KSA03068.1 - 0.00056 20.2 0.6 0.0011 19.3 0.6 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain DUF2407 PF10302.9 KSA03068.1 - 0.0017 18.9 0.0 0.0037 17.8 0.0 1.6 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain UBA_3 PF09288.10 KSA03068.1 - 0.038 13.8 0.0 5.9 6.8 0.0 2.6 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain UBA_2 PF08587.11 KSA03068.1 - 0.05 13.7 0.1 0.4 10.8 0.0 2.3 2 0 0 2 2 2 0 Ubiquitin associated domain (UBA) DUF2239 PF09998.9 KSA03068.1 - 0.06 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2239) Rap1_C PF11626.8 KSA03068.1 - 0.14 12.3 0.0 3.6 7.7 0.0 2.5 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain DUF3306 PF11748.8 KSA03068.1 - 0.82 10.6 6.1 0.32 11.9 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) ADK_lid PF05191.14 KSA03069.1 - 0.0045 17.0 1.2 0.016 15.2 1.2 2.0 1 0 0 1 1 1 1 Adenylate kinase, active site lid SAM_DrpA PF18255.1 KSA03069.1 - 0.011 15.9 0.0 0.028 14.6 0.0 1.7 1 0 0 1 1 1 0 DNA processing protein A sterile alpha motif domain C1_1 PF00130.22 KSA03069.1 - 0.068 13.1 0.5 0.14 12.0 0.5 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) NPBW PF15180.6 KSA03069.1 - 0.083 12.7 0.3 0.22 11.4 0.3 1.6 1 0 0 1 1 1 0 Neuropeptides B and W Ribosomal_L37 PF08561.10 KSA03069.1 - 6.9 7.2 8.8 2.2 8.8 4.1 2.1 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L37 Retrotrans_gag PF03732.17 KSA03070.1 - 0.015 15.6 9.8 2.5 8.4 0.2 4.0 2 2 1 3 3 3 0 Retrotransposon gag protein PWI PF01480.17 KSA03071.1 - 0.00023 21.4 0.5 0.00023 21.4 0.5 2.8 3 0 0 3 3 3 1 PWI domain ABC_tran_Xtn PF12848.7 KSA03071.1 - 0.012 15.7 2.2 0.012 15.7 2.2 3.4 3 1 1 4 4 4 0 ABC transporter IPT PF01745.16 KSA03071.1 - 0.012 15.0 1.5 0.019 14.4 0.1 2.0 2 0 0 2 2 2 0 Isopentenyl transferase Ecl1 PF12855.7 KSA03074.1 - 1.8e-12 48.8 4.1 2.1e-12 48.5 4.1 1.0 1 0 0 1 1 1 1 ECL1/2/3 zinc binding proteins Mating_C PF12737.7 KSA03074.1 - 0.066 12.4 0.0 0.084 12.1 0.0 1.1 1 0 0 1 1 1 0 C-terminal domain of homeodomain 1 DUF3079 PF11278.8 KSA03074.1 - 0.37 10.6 3.0 0.91 9.4 3.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3079) DUF2116 PF09889.9 KSA03074.1 - 1.3 9.0 4.6 2.2 8.3 4.6 1.3 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) L31 PF09784.9 KSA03075.1 - 3.2e-43 146.3 2.4 3.6e-43 146.1 2.4 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 Spc24 PF08286.11 KSA03076.1 - 1.4e-26 92.7 14.9 3.4e-26 91.5 9.1 2.2 2 0 0 2 2 2 2 Spc24 subunit of Ndc80 FlaC_arch PF05377.11 KSA03076.1 - 0.44 11.0 10.4 3.9 7.9 3.8 2.8 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.12 KSA03076.1 - 0.76 9.8 4.4 4.4 7.4 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Cmc1 PF08583.10 KSA03077.1 - 8.4e-17 61.0 4.3 1.2e-16 60.5 4.3 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Ndufs5 PF10200.9 KSA03077.1 - 0.0053 17.0 0.4 0.0066 16.7 0.4 1.3 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DASH_Hsk3 PF08227.11 KSA03078.1 - 8.7e-20 70.8 2.5 1.5e-19 70.1 2.5 1.4 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like Hap4_Hap_bind PF10297.9 KSA03079.1 - 1.1e-07 31.7 10.5 3.4e-07 30.2 10.5 1.9 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 Sdh_cyt PF01127.22 KSA03080.1 - 6e-29 100.5 1.4 7.4e-29 100.2 1.4 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit FYVE PF01363.21 KSA03081.1 - 5.6e-15 55.2 5.7 1e-14 54.4 5.7 1.4 1 0 0 1 1 1 1 FYVE zinc finger zf-AN1 PF01428.16 KSA03081.1 - 0.033 14.3 8.4 0.075 13.2 8.4 1.6 1 0 0 1 1 1 0 AN1-like Zinc finger HNH_5 PF14279.6 KSA03081.1 - 0.036 13.9 3.0 0.11 12.4 3.0 1.8 1 0 0 1 1 1 0 HNH endonuclease Adeno_E1A PF02703.14 KSA03081.1 - 0.071 12.7 4.7 0.12 11.9 0.9 2.4 1 1 1 2 2 2 0 Early E1A protein STT3 PF02516.14 KSA03082.1 - 1.2e-156 522.5 41.8 8.2e-153 509.8 38.9 2.3 3 0 0 3 3 3 2 Oligosaccharyl transferase STT3 subunit PMT_2 PF13231.6 KSA03082.1 - 0.0022 18.2 12.3 0.0022 18.2 12.3 3.5 4 1 0 4 4 4 1 Dolichyl-phosphate-mannose-protein mannosyltransferase DUF962 PF06127.11 KSA03083.1 - 3.5e-22 78.3 0.0 5.5e-22 77.7 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF962) DUF1240 PF06836.12 KSA03083.1 - 0.4 11.2 5.2 2.3 8.8 0.0 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1240) MT-A70 PF05063.14 KSA03084.1 - 1.3e-49 168.4 0.1 2.3e-49 167.6 0.1 1.3 1 0 0 1 1 1 1 MT-A70 TFIID_30kDa PF03540.13 KSA03086.1 - 2e-24 85.3 0.1 2e-24 85.3 0.1 2.0 2 0 0 2 2 2 1 Transcription initiation factor TFIID 23-30kDa subunit Zn_ribbon_17 PF17120.5 KSA03087.1 - 3.8e-17 61.7 13.0 7.5e-17 60.7 13.0 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type WD40 PF00400.32 KSA03087.1 - 0.0055 17.5 19.7 0.022 15.6 0.1 5.7 5 0 0 5 5 5 2 WD domain, G-beta repeat zf-C3HC4 PF00097.25 KSA03087.1 - 0.0076 16.1 8.8 0.018 14.9 8.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RWD PF05773.22 KSA03087.1 - 0.078 13.3 1.0 0.29 11.4 1.0 2.0 1 0 0 1 1 1 0 RWD domain zf-RING_2 PF13639.6 KSA03087.1 - 0.1 12.9 7.7 0.24 11.8 7.7 1.6 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.6 KSA03087.1 - 0.12 12.3 4.4 0.25 11.2 4.4 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 KSA03087.1 - 0.91 9.9 8.9 1.8 8.9 8.9 1.5 1 0 0 1 1 1 0 RING-like domain zinc_ribbon_16 PF17034.5 KSA03087.1 - 4.3 7.6 13.5 0.95 9.7 6.6 2.8 2 0 0 2 2 2 0 Zinc-ribbon like family adh_short PF00106.25 KSA03088.1 - 1.5e-11 44.2 0.0 4.6e-10 39.3 0.0 2.8 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KSA03088.1 - 1.8e-06 27.7 0.0 0.029 13.9 0.0 3.0 2 1 1 3 3 3 2 Enoyl-(Acyl carrier protein) reductase CLTH PF10607.9 KSA03088.1 - 0.065 13.1 0.0 0.11 12.4 0.0 1.4 1 1 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain Pkinase PF00069.25 KSA03089.1 - 6.1e-66 222.5 0.0 7.5e-66 222.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KSA03089.1 - 2.6e-31 108.9 0.0 3.8e-31 108.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KSA03089.1 - 0.00012 21.2 0.4 0.00019 20.5 0.4 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KSA03089.1 - 0.0068 15.8 0.1 0.0097 15.3 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KSA03089.1 - 0.012 15.2 0.1 0.019 14.6 0.1 1.3 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 KSA03089.1 - 0.031 14.2 0.1 0.063 13.2 0.1 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 KSA03089.1 - 0.12 12.0 0.2 0.64 9.6 0.0 2.0 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 MFS_1 PF07690.16 KSA03090.1 - 6.7e-35 120.7 17.9 6.7e-35 120.7 17.9 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Jagunal PF07086.12 KSA03090.1 - 0.097 12.7 1.9 0.72 9.9 1.4 2.6 2 1 1 3 3 3 0 Jagunal, ER re-organisation during oogenesis DUF2951 PF11166.8 KSA03090.1 - 0.4 10.9 1.9 4.3 7.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) DUF1774 PF08611.10 KSA03090.1 - 3.7 7.9 6.1 16 5.9 0.2 3.2 3 1 0 3 3 3 0 Fungal protein of unknown function (DUF1774) HECT PF00632.25 KSA03091.1 - 5.2e-78 262.6 0.8 2.7e-77 260.3 0.0 2.3 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) Sigma70_ner PF04546.13 KSA03091.1 - 1.5 8.6 22.7 12 5.7 0.0 3.5 3 0 0 3 3 3 0 Sigma-70, non-essential region F-actin_cap_A PF01267.17 KSA03092.1 - 6.7e-71 238.8 1.4 7.6e-71 238.6 1.4 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit VHS PF00790.19 KSA03093.1 - 3.5e-32 111.2 1.2 7e-32 110.2 1.2 1.5 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.28 KSA03093.1 - 3.4e-15 55.4 0.0 7.3e-15 54.3 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KSA03093.1 - 1.9e-13 50.0 0.0 3.8e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KSA03093.1 - 2.4e-12 46.3 0.0 5.6e-12 45.2 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.14 KSA03093.1 - 3e-06 27.4 1.0 3e-06 27.4 1.0 3.1 4 1 0 4 4 4 1 GAT domain UIM PF02809.20 KSA03093.1 - 0.00064 19.5 1.0 0.0019 18.0 1.0 1.9 1 0 0 1 1 1 1 Ubiquitin interaction motif RTP1_C1 PF10363.9 KSA03093.1 - 0.029 14.5 0.1 0.11 12.7 0.1 2.0 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 1 FRB_dom PF08771.11 KSA03093.1 - 0.09 13.2 1.2 6.7 7.2 0.0 3.3 2 1 2 4 4 4 0 FKBP12-rapamycin binding domain IF2_N PF04760.15 KSA03093.1 - 0.48 10.3 2.8 15 5.5 1.0 3.1 2 1 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region TRAM_LAG1_CLN8 PF03798.16 KSA03094.1 - 6e-38 130.6 21.8 6e-38 130.6 21.8 2.1 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 KSA03094.1 - 1.2e-20 73.0 1.8 1.5e-20 72.6 0.3 2.0 2 0 0 2 2 2 1 TRAM1-like protein Ribosomal_S2 PF00318.20 KSA03096.1 - 9.1e-68 227.7 1.0 1.1e-66 224.1 0.0 2.5 2 1 0 2 2 2 1 Ribosomal protein S2 FAM117 PF15388.6 KSA03096.1 - 0.023 14.1 6.3 0.035 13.5 6.3 1.2 1 0 0 1 1 1 0 Protein Family FAM117 GBR2_CC PF18455.1 KSA03096.1 - 0.052 13.7 0.1 0.15 12.2 0.1 1.7 1 0 0 1 1 1 0 Gamma-aminobutyric acid type B receptor subunit 2 coiled-coil domain CS PF04969.16 KSA03098.1 - 0.0053 17.7 0.1 0.013 16.5 0.0 1.6 2 0 0 2 2 2 1 CS domain Phageshock_PspG PF09583.10 KSA03099.1 - 0.25 11.7 0.1 0.37 11.1 0.1 1.2 1 0 0 1 1 1 0 Phage shock protein G (Phageshock_PspG) Syja_N PF02383.18 KSA03100.1 - 3.8e-79 266.3 1.6 3.8e-79 266.3 1.6 2.3 2 0 0 2 2 2 1 SacI homology domain DUF3156 PF11354.8 KSA03100.1 - 0.14 12.0 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3156) Mito_carr PF00153.27 KSA03101.1 - 1.2e-55 185.4 2.9 3.8e-17 62.0 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein AXE1 PF05448.12 KSA03101.1 - 0.12 11.0 0.1 0.22 10.1 0.1 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) UCR_14kD PF02271.16 KSA03102.1 - 3.9e-37 126.2 0.0 4.6e-37 126.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit ATP_transf PF09830.9 KSA03103.1 - 2.5e-19 69.2 0.0 5.3e-19 68.1 0.0 1.6 1 0 0 1 1 1 1 ATP adenylyltransferase HIT PF01230.23 KSA03103.1 - 0.011 16.4 0.0 0.041 14.6 0.0 1.8 2 0 0 2 2 2 0 HIT domain DUF4922 PF16269.5 KSA03103.1 - 0.045 13.5 0.3 0.08 12.7 0.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4922) DUF4931 PF16285.5 KSA03103.1 - 0.05 12.9 0.0 0.12 11.6 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4931) DUF4850 PF16142.5 KSA03103.1 - 0.16 11.5 0.0 0.41 10.1 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4850) Spb1_C PF07780.12 KSA03105.1 - 4.5e-81 271.5 22.7 4.5e-81 271.5 22.7 3.2 3 0 0 3 3 3 1 Spb1 C-terminal domain FtsJ PF01728.19 KSA03105.1 - 6.5e-53 179.5 0.0 1.3e-52 178.5 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.8 KSA03105.1 - 6.9e-43 146.3 16.0 6.9e-43 146.3 16.0 5.5 4 1 1 5 5 5 1 Domain of unknown function (DUF3381) Methyltransf_23 PF13489.6 KSA03105.1 - 0.057 13.3 0.1 0.29 10.9 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Pep3_Vps18 PF05131.14 KSA03106.1 - 3.8e-27 94.9 1.2 2.2e-26 92.5 0.9 2.5 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Vps39_2 PF10367.9 KSA03106.1 - 9.8e-06 26.0 1.0 3.7e-05 24.1 1.0 2.1 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Zn_ribbon_17 PF17120.5 KSA03106.1 - 0.0047 16.5 1.4 0.013 15.1 1.4 1.7 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 KSA03106.1 - 0.011 15.7 4.0 0.038 14.0 4.0 1.9 1 0 0 1 1 1 0 RING-type zinc-finger TPR_1 PF00515.28 KSA03106.1 - 0.03 14.2 2.9 0.098 12.5 1.4 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-C3HC4_2 PF13923.6 KSA03106.1 - 0.035 13.9 4.8 0.099 12.5 4.8 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TPR_2 PF07719.17 KSA03106.1 - 0.11 12.6 3.5 0.24 11.6 1.5 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Zf_RING PF16744.5 KSA03106.1 - 0.12 12.5 0.7 0.27 11.4 0.7 1.6 1 0 0 1 1 1 0 KIAA1045 RING finger zf-C3HC4 PF00097.25 KSA03106.1 - 0.15 11.9 8.4 0.094 12.6 4.8 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF16 PF01519.16 KSA03106.1 - 0.31 11.5 4.3 1.7 9.2 0.6 2.9 2 0 0 2 2 2 0 Protein of unknown function DUF16 zf-rbx1 PF12678.7 KSA03106.1 - 0.44 10.9 4.9 0.25 11.7 1.9 2.1 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-RING_11 PF17123.5 KSA03106.1 - 0.5 10.2 8.8 1.3 8.8 8.8 1.7 1 0 0 1 1 1 0 RING-like zinc finger TPR_11 PF13414.6 KSA03106.1 - 1.4 8.7 4.4 1.1 9.0 1.0 2.7 2 0 0 2 2 2 0 TPR repeat zf-RING-like PF08746.11 KSA03106.1 - 1.6 9.1 7.6 0.29 11.5 3.5 1.9 2 0 0 2 2 2 0 RING-like domain zf-RING_5 PF14634.6 KSA03106.1 - 1.7 8.7 5.2 4.7 7.3 5.2 1.7 1 0 0 1 1 1 0 zinc-RING finger domain SRP_TPR_like PF17004.5 KSA03106.1 - 7.3 6.6 8.9 1.3 9.0 0.6 4.0 4 2 0 4 4 4 0 Putative TPR-like repeat zf-RING_2 PF13639.6 KSA03106.1 - 9.5 6.6 13.9 0.03 14.7 4.0 2.0 3 0 0 3 3 1 0 Ring finger domain CH PF00307.31 KSA03107.1 - 6.8e-79 261.1 1.2 1.6e-21 76.5 0.0 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KSA03107.1 - 1.3e-06 28.1 0.0 0.57 10.1 0.0 4.4 4 0 0 4 4 4 3 CAMSAP CH domain EF-hand_7 PF13499.6 KSA03107.1 - 0.00012 22.4 0.5 0.0006 20.2 0.3 2.3 2 0 0 2 2 2 1 EF-hand domain pair CH_2 PF06294.11 KSA03107.1 - 0.00014 21.9 0.1 2.3 8.4 0.0 3.6 3 0 0 3 3 3 2 CH-like domain in sperm protein EF-hand_1 PF00036.32 KSA03107.1 - 0.0059 16.1 0.1 0.11 12.1 0.0 2.6 2 0 0 2 2 2 1 EF hand Complex1_LYR PF05347.15 KSA03108.1 - 4.2e-09 36.3 1.0 6.7e-09 35.7 1.0 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) RL10P_insert PF17777.1 KSA03110.1 - 1.3e-18 66.7 0.0 2.1e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 KSA03110.1 - 1.2e-16 60.6 0.0 2.6e-16 59.6 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L10 CENP-C_C PF11699.8 KSA03111.1 - 1.3e-22 79.8 1.4 2.1e-22 79.1 0.6 1.8 2 0 0 2 2 2 1 Mif2/CENP-C like Cupin_2 PF07883.11 KSA03111.1 - 3e-06 26.9 0.0 6.5e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 Cupin domain MannoseP_isomer PF01050.18 KSA03111.1 - 0.00096 19.1 0.0 0.0018 18.2 0.0 1.4 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase Mif2_N PF15624.6 KSA03111.1 - 0.0011 19.7 7.0 0.0011 19.7 7.0 3.6 3 1 0 3 3 3 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal CRT10 PF08728.10 KSA03112.1 - 2.5e-193 644.2 7.4 1.8e-130 436.4 3.1 3.1 2 1 1 3 3 3 2 CRT10 Presenilin PF01080.17 KSA03112.1 - 6.5 5.4 8.9 11 4.7 8.9 1.3 1 0 0 1 1 1 0 Presenilin GAF_2 PF13185.6 KSA03113.1 - 3e-11 43.7 0.0 4.6e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 KSA03113.1 - 2.4e-07 31.5 0.0 2.6e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 KSA03113.1 - 0.0045 17.3 0.0 0.0077 16.6 0.0 1.3 1 0 0 1 1 1 1 GAF domain SpoVT_C PF15714.5 KSA03113.1 - 0.04 14.0 0.0 0.06 13.4 0.0 1.3 1 0 0 1 1 1 0 Stage V sporulation protein T C-terminal, transcription factor KH_1 PF00013.29 KSA03114.1 - 1.3e-37 127.4 0.9 5.2e-14 51.8 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 KSA03114.1 - 1.4e-10 40.9 3.9 0.017 15.0 0.0 3.6 4 0 0 4 4 4 3 KH domain KH_2 PF07650.17 KSA03114.1 - 2.1e-09 37.0 4.0 0.018 14.9 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 KSA03114.1 - 9.7e-08 32.0 0.9 0.065 13.3 0.2 3.4 3 0 0 3 3 3 3 NusA-like KH domain DUF1480 PF07351.13 KSA03115.1 - 0.018 15.3 0.2 1.4 9.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1480) DUF823 PF05689.11 KSA03115.1 - 0.066 13.0 1.1 0.1 12.4 1.1 1.2 1 0 0 1 1 1 0 Salmonella repeat of unknown function (DUF823) Peptidase_A22B PF04258.13 KSA03116.1 - 3.8e-64 217.0 6.8 3.8e-64 217.0 6.8 1.8 2 1 0 2 2 2 1 Signal peptide peptidase SPP PF06550.11 KSA03116.1 - 2.8e-07 30.3 2.4 2.8e-07 30.3 2.4 2.2 3 0 0 3 3 3 1 Signal-peptide peptidase, presenilin aspartyl protease Hum_adeno_E3A PF05393.11 KSA03116.1 - 0.11 12.5 0.0 0.3 11.1 0.0 1.7 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein Pox_A14 PF05767.12 KSA03116.1 - 0.87 9.8 7.1 16 5.7 0.0 3.5 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 SRP54_N PF02881.19 KSA03118.1 - 2.1e-17 63.1 3.1 3.5e-17 62.4 3.1 1.3 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain Tweety PF04906.13 KSA03118.1 - 0.0014 17.4 0.2 0.0017 17.1 0.2 1.0 1 0 0 1 1 1 1 Tweety RDV-p3 PF09231.10 KSA03118.1 - 0.0025 15.7 0.1 0.0028 15.5 0.1 1.0 1 0 0 1 1 1 1 Rice dwarf virus p3 DUF4239 PF14023.6 KSA03118.1 - 0.088 12.5 0.3 0.1 12.3 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) GLE1 PF07817.13 KSA03118.1 - 0.33 10.1 2.5 0.37 10.0 2.5 1.2 1 0 0 1 1 1 0 GLE1-like protein SRP_SPB PF02978.19 KSA03119.1 - 1.2e-28 99.6 6.8 1.2e-28 99.6 6.8 4.0 3 1 1 4 4 4 1 Signal peptide binding domain SRP54 PF00448.22 KSA03119.1 - 2.2e-28 99.2 0.7 1.1e-27 97.0 0.3 2.1 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain STI1 PF17830.1 KSA03119.1 - 2.3 8.2 42.2 0.21 11.5 21.8 3.4 3 0 0 3 3 3 0 STI1 domain XPC-binding PF09280.11 KSA03119.1 - 5.4 6.8 21.7 6.7 6.5 6.9 3.5 2 1 1 3 3 3 0 XPC-binding domain LRR_4 PF12799.7 KSA03120.1 - 0.23 12.0 0.0 0.23 12.0 0.0 6.6 6 1 1 7 7 7 0 Leucine Rich repeats (2 copies) MSA-2c PF12238.8 KSA03120.1 - 8 6.4 13.2 0.073 13.1 2.8 2.9 3 0 0 3 3 3 0 Merozoite surface antigen 2c Elf1 PF05129.13 KSA03121.1 - 3.7e-30 103.8 3.0 4.7e-30 103.5 3.0 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like DUF2688 PF10892.8 KSA03121.1 - 0.052 13.0 0.4 0.11 12.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2688) EST1_DNA_bind PF10373.9 KSA03121.1 - 0.088 12.3 0.0 0.099 12.1 0.0 1.1 1 0 0 1 1 1 0 Est1 DNA/RNA binding domain Zn-ribbon_8 PF09723.10 KSA03121.1 - 0.093 12.9 1.9 0.45 10.7 2.1 1.9 1 1 1 2 2 2 0 Zinc ribbon domain Pox_A51 PF04948.13 KSA03121.1 - 0.14 11.0 1.6 0.17 10.7 1.6 1.1 1 0 0 1 1 1 0 Poxvirus A51 protein RabGAP-TBC PF00566.18 KSA03122.1 - 3.8e-14 52.9 2.2 3.8e-14 52.9 2.2 1.6 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Bac_surface_Ag PF01103.23 KSA03123.1 - 2.3e-07 30.6 19.2 7.6e-07 28.9 19.2 1.8 1 1 0 1 1 1 1 Surface antigen CbiA PF01656.23 KSA03123.1 - 0.076 13.1 0.0 0.49 10.4 0.0 2.0 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain GHMP_kinases_N PF00288.26 KSA03124.1 - 3.6e-10 39.9 0.0 6.9e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KSA03124.1 - 0.00047 20.5 0.0 0.0012 19.2 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal p450 PF00067.22 KSA03125.1 - 1.3e-95 320.9 0.0 1.5e-95 320.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HLH PF00010.26 KSA03126.1 - 2.7e-15 56.1 0.0 2.7e-15 56.1 0.0 2.2 3 0 0 3 3 3 1 Helix-loop-helix DNA-binding domain Methyltransf_4 PF02390.17 KSA03127.1 - 0.16 11.4 1.4 0.3 10.5 0.0 2.1 2 0 0 2 2 2 0 Putative methyltransferase RRN3 PF05327.11 KSA03127.1 - 2.1 6.8 7.1 3 6.3 7.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Peptidase_M16_C PF05193.21 KSA03128.1 - 1.6e-41 142.3 0.0 7.7e-41 140.1 0.0 2.1 3 0 0 3 3 3 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KSA03128.1 - 3.5e-35 121.2 0.0 8.1e-35 120.0 0.0 1.6 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Myosin_head PF00063.21 KSA03129.1 - 1.5e-260 866.2 21.2 1.5e-260 866.2 21.2 2.3 2 0 0 2 2 2 1 Myosin head (motor domain) CENP-F_leu_zip PF10473.9 KSA03129.1 - 0.0065 16.5 7.2 0.0065 16.5 7.2 13.4 3 2 11 14 14 14 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Myosin_N PF02736.19 KSA03129.1 - 0.0079 16.0 0.1 0.019 14.8 0.1 1.6 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_22 PF13401.6 KSA03129.1 - 0.037 14.3 3.1 0.18 12.1 0.0 4.0 4 0 0 4 4 4 0 AAA domain AAA_19 PF13245.6 KSA03129.1 - 0.22 11.8 4.0 0.84 10.0 0.0 3.3 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KSA03129.1 - 2 8.8 0.0 2 8.8 0.0 3.5 4 0 0 4 4 4 0 AAA ATPase domain MATalpha_HMGbox PF04769.12 KSA03130.1 - 3.6e-14 52.5 1.0 5.1e-14 52.0 0.8 1.3 1 1 0 1 1 1 1 Mating-type protein MAT alpha 1 HMG-box DUF3959 PF13105.6 KSA03130.1 - 0.11 12.0 0.3 0.19 11.2 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) Pirin PF02678.16 KSA03131.1 - 6.5e-27 93.6 0.1 1.1e-26 92.9 0.1 1.4 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 KSA03131.1 - 3.4e-16 59.5 0.0 1.4e-15 57.6 0.0 1.8 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 KSA03131.1 - 0.13 12.0 0.7 0.77 9.5 1.1 2.0 2 1 0 2 2 2 0 Cupin domain DrrA_P4M PF14860.6 KSA03132.1 - 0.048 13.5 6.2 0.12 12.2 0.7 3.4 3 0 0 3 3 3 0 DrrA phosphatidylinositol 4-phosphate binding domain DUF3677 PF12432.8 KSA03132.1 - 0.15 12.4 1.6 0.77 10.1 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3677) Sec10 PF07393.11 KSA03133.1 - 1.5e-82 278.2 22.4 1.9e-82 277.8 22.4 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box PF00646.33 KSA03133.1 - 0.023 14.6 0.0 0.06 13.3 0.0 1.7 1 0 0 1 1 1 0 F-box domain DUF3310 PF11753.8 KSA03134.1 - 0.015 15.5 0.1 0.043 14.0 0.1 1.7 1 0 0 1 1 1 0 Protein of unknwon function (DUF3310) RepA_C PF04796.12 KSA03134.1 - 0.081 12.9 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Plasmid encoded RepA protein Ribosomal_L31 PF01197.18 KSA03135.1 - 0.081 13.2 0.0 0.29 11.4 0.0 2.0 1 1 0 2 2 2 0 Ribosomal protein L31 Cpn60_TCP1 PF00118.24 KSA03136.1 - 1.7e-155 518.4 7.3 2e-155 518.2 7.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Pcc1 PF09341.10 KSA03137.1 - 2.6e-17 62.7 0.0 3.4e-17 62.3 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Pcc1 FGF-BP1 PF06473.12 KSA03137.1 - 0.033 14.0 0.0 0.037 13.8 0.0 1.1 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) Methyltransf_28 PF02636.17 KSA03138.1 - 7.8e-37 127.3 0.1 2e-36 126.0 0.0 1.7 2 0 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Occludin_ELL PF07303.13 KSA03138.1 - 0.017 15.8 3.9 0.017 15.8 3.9 2.8 3 0 0 3 3 3 0 Occludin homology domain DUF3552 PF12072.8 KSA03138.1 - 0.31 10.4 3.3 1.3 8.4 2.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) MFS_1 PF07690.16 KSA03139.1 - 4.7e-20 71.8 13.4 7.4e-20 71.2 11.2 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily XRN_M PF17846.1 KSA03140.1 - 4.8e-136 454.2 4.0 4.8e-136 454.2 4.0 2.8 2 1 0 2 2 2 1 Xrn1 helical domain XRN_N PF03159.18 KSA03140.1 - 3.5e-98 327.9 0.0 9.9e-98 326.4 0.0 1.8 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus DAGK_cat PF00781.24 KSA03141.1 - 1.4e-13 50.6 0.0 2.5e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Sugar_tr PF00083.24 KSA03142.1 - 1.5e-67 228.5 14.2 1.9e-67 228.1 14.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KSA03142.1 - 2.1e-14 53.2 15.9 3.2e-14 52.6 15.9 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1634 PF07843.11 KSA03142.1 - 0.052 13.6 3.2 0.25 11.5 1.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1634) Gti1_Pac2 PF09729.9 KSA03143.1 - 2.8e-52 177.4 0.2 2.8e-52 177.4 0.2 2.8 2 1 0 2 2 2 1 Gti1/Pac2 family Pkinase PF00069.25 KSA03144.1 - 7.7e-70 235.3 0.6 7.7e-70 235.3 0.6 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KSA03144.1 - 4.6e-53 180.1 0.2 8.4e-53 179.3 0.2 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 KSA03144.1 - 5.2e-23 81.2 0.3 5.2e-23 81.2 0.3 3.3 4 0 0 4 4 3 1 P21-Rho-binding domain PH PF00169.29 KSA03144.1 - 4.3e-09 36.8 0.2 1.2e-08 35.4 0.2 1.8 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 KSA03144.1 - 2.6e-08 33.5 0.1 1.3e-07 31.3 0.0 1.9 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KSA03144.1 - 6.8e-07 28.4 0.0 6.8e-07 28.4 0.0 2.2 3 0 0 3 3 3 1 Fungal protein kinase Haspin_kinase PF12330.8 KSA03144.1 - 1.1e-06 27.9 1.5 1.1e-06 27.9 1.5 2.0 2 0 0 2 2 2 1 Haspin like kinase domain PH_11 PF15413.6 KSA03144.1 - 0.0038 17.6 0.2 0.025 15.0 0.0 2.5 1 1 1 2 2 2 1 Pleckstrin homology domain Seadorna_VP7 PF07387.11 KSA03144.1 - 0.008 15.3 0.0 0.019 14.1 0.0 1.5 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.23 KSA03144.1 - 0.012 15.6 0.1 0.04 13.8 0.1 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family LepB_GAP_C PF18227.1 KSA03144.1 - 0.1 13.1 0.1 0.27 11.8 0.1 1.7 1 0 0 1 1 1 0 LepB GAP domain C-terminal subdomain FTA2 PF13095.6 KSA03144.1 - 4.1 7.0 6.0 2.4 7.7 0.2 2.8 1 1 2 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Pkinase PF00069.25 KSA03145.1 - 2.7e-28 99.1 0.0 1.1e-27 97.0 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KSA03145.1 - 5.2e-12 45.6 0.0 1e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase NTF-like PF14540.6 KSA03145.1 - 0.067 13.0 0.0 0.18 11.6 0.0 1.7 1 0 0 1 1 1 0 Nucleotidyltransferase-like Cwf_Cwc_15 PF04889.12 KSA03145.1 - 3.1 7.5 14.2 1 9.1 10.5 1.9 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Pkinase PF00069.25 KSA03146.1 - 2.2e-70 237.1 0.0 2.8e-70 236.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KSA03146.1 - 6.5e-39 133.8 0.0 9e-39 133.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KSA03146.1 - 1.7e-05 24.3 0.0 3.7e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KSA03146.1 - 0.035 13.0 0.1 0.06 12.3 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain RraA-like PF03737.15 KSA03148.1 - 2.7e-31 108.7 0.0 3.4e-31 108.4 0.0 1.1 1 0 0 1 1 1 1 Aldolase/RraA Wtap PF17098.5 KSA03149.1 - 0.03 14.3 7.7 0.96 9.4 0.4 3.0 2 1 1 3 3 3 0 WTAP/Mum2p family RNA_polI_A34 PF08208.11 KSA03150.1 - 1.1e-37 130.1 21.2 1.5e-37 129.7 21.2 1.1 1 0 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 Glypican PF01153.19 KSA03150.1 - 0.36 9.6 6.5 0.44 9.3 6.5 1.1 1 0 0 1 1 1 0 Glypican Presenilin PF01080.17 KSA03150.1 - 2.1 7.0 5.6 2 7.1 5.6 1.1 1 0 0 1 1 1 0 Presenilin Gate PF07670.14 KSA03151.1 - 0.0023 18.2 5.1 3.5 7.9 3.7 4.0 2 1 1 3 3 3 1 Nucleoside recognition TMEM18 PF14770.6 KSA03151.1 - 2.2 8.3 7.1 1.6 8.7 3.0 2.4 2 0 0 2 2 2 0 Transmembrane protein 18 Virul_fac_BrkB PF03631.15 KSA03152.1 - 0.00028 20.6 2.1 0.00028 20.6 2.1 1.7 1 1 0 1 1 1 1 Virulence factor BrkB Rab5ip PF07019.12 KSA03152.1 - 0.0035 17.9 0.7 0.0035 17.9 0.7 3.3 4 0 0 4 4 4 1 Rab5-interacting protein (Rab5ip) Otopetrin PF03189.13 KSA03153.1 - 0.0075 15.1 0.3 0.0099 14.7 0.3 1.1 1 0 0 1 1 1 1 Otopetrin Mito_carr PF00153.27 KSA03155.1 - 3.5e-44 148.7 5.3 2.4e-16 59.4 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein dsrm PF00035.26 KSA03156.1 - 1.4e-10 41.7 0.0 6.3e-07 30.0 0.0 2.6 2 0 0 2 2 2 2 Double-stranded RNA binding motif Ribonucleas_3_3 PF14622.6 KSA03156.1 - 0.00089 19.4 0.1 0.002 18.3 0.1 1.6 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 KSA03156.1 - 0.00099 19.7 1.8 0.0016 19.0 0.1 2.3 2 1 0 2 2 2 1 Ribonuclease III domain RNase_3_N PF18497.1 KSA03156.1 - 0.039 14.2 0.1 0.16 12.2 0.1 2.1 2 0 0 2 2 2 0 Ribonuclease III N-terminal domain MFS_1 PF07690.16 KSA03157.1 - 2.3e-34 118.9 9.7 2.3e-34 118.9 9.7 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily TMEM234 PF10639.9 KSA03157.1 - 3.2 7.8 6.1 24 5.0 0.0 3.2 3 0 0 3 3 3 0 Putative transmembrane family 234 Pox_A14 PF05767.12 KSA03157.1 - 3.9 7.7 6.5 1.5 9.0 1.8 2.6 2 1 1 3 3 3 0 Poxvirus virion envelope protein A14 FoP_duplication PF13865.6 KSA03158.1 - 9.4e-14 51.7 1.7 9.4e-14 51.7 1.7 2.4 2 0 0 2 2 2 2 C-terminal duplication domain of Friend of PRMT1 RRM_1 PF00076.22 KSA03158.1 - 0.0055 16.5 0.0 0.01 15.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Bac_small_YrzI PF09501.10 KSA03158.1 - 0.11 12.6 0.2 0.28 11.3 0.2 1.6 1 0 0 1 1 1 0 Probable sporulation protein (Bac_small_yrzI) Syja_N PF02383.18 KSA03159.1 - 8.3e-81 271.8 1.7 1.1e-80 271.3 1.7 1.2 1 0 0 1 1 1 1 SacI homology domain PFU PF09070.11 KSA03160.1 - 3.3e-41 140.1 0.1 6.5e-41 139.1 0.1 1.5 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) PUL PF08324.11 KSA03160.1 - 1.9e-40 138.9 5.8 2.6e-40 138.4 5.8 1.2 1 0 0 1 1 1 1 PUL domain WD40 PF00400.32 KSA03160.1 - 3.3e-34 116.3 24.5 7.9e-06 26.5 0.0 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KSA03160.1 - 0.0018 18.6 0.2 0.23 11.8 0.0 3.9 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KSA03160.1 - 0.013 14.8 0.0 0.12 11.6 0.0 2.3 2 0 0 2 2 2 0 WD40-like domain Rep_fac-A_3 PF08661.11 KSA03161.1 - 4.3e-28 97.7 0.0 4.8e-28 97.6 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 Ten1_2 PF15490.6 KSA03161.1 - 0.14 11.8 0.0 0.43 10.3 0.0 1.9 1 1 0 1 1 1 0 Telomere-capping, CST complex subunit IGPS PF00218.21 KSA03162.1 - 3.7e-70 236.0 0.1 5.1e-70 235.5 0.1 1.1 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase GATase PF00117.28 KSA03162.1 - 3.6e-45 154.1 0.1 5.4e-45 153.5 0.1 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KSA03162.1 - 4.9e-07 29.7 0.1 1.1e-06 28.6 0.1 1.6 1 0 0 1 1 1 1 Peptidase C26 PigN PF04987.14 KSA03163.1 - 6.4e-138 460.4 46.7 8.2e-138 460.1 46.7 1.1 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 KSA03163.1 - 3.6e-11 43.3 0.7 7.4e-09 35.6 0.2 2.2 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KSA03163.1 - 6e-08 32.4 0.0 1.8e-07 30.8 0.0 1.6 1 1 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 KSA03163.1 - 4.8e-06 26.1 0.0 7.6e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Bac_export_2 PF01312.19 KSA03163.1 - 7.4 5.7 6.3 0.88 8.7 0.2 2.2 2 0 0 2 2 2 0 FlhB HrpN YscU SpaS Family DnaJ PF00226.31 KSA03164.1 - 6.4e-23 80.6 3.2 6.4e-23 80.6 3.2 2.9 4 0 0 4 4 4 1 DnaJ domain DUF4199 PF13858.6 KSA03164.1 - 0.47 10.9 3.4 1.1 9.7 3.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4199) CRAL_TRIO PF00650.20 KSA03165.1 - 2.2e-19 69.7 0.0 3.8e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KSA03165.1 - 7e-06 26.1 0.0 1.6e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Prok_Ub PF14454.6 KSA03165.1 - 0.019 14.6 0.0 0.042 13.5 0.0 1.7 1 0 0 1 1 1 0 Prokaryotic Ubiquitin GP11 PF08677.10 KSA03165.1 - 0.032 13.7 0.0 0.053 13.0 0.0 1.4 1 0 0 1 1 1 0 GP11 baseplate wedge protein MMR_HSR1_C PF08438.10 KSA03166.1 - 1.1e-33 116.1 0.0 2e-33 115.3 0.0 1.4 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 KSA03166.1 - 2.8e-20 72.5 0.0 6.4e-20 71.3 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KSA03166.1 - 6.4e-09 35.5 0.2 2.3e-07 30.5 0.0 2.6 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KSA03166.1 - 0.0015 18.4 1.4 1.5 8.7 0.1 2.6 3 0 0 3 3 3 2 RsgA GTPase GTP_EFTU PF00009.27 KSA03166.1 - 0.0034 17.0 2.2 0.26 10.8 0.1 3.1 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 KSA03166.1 - 0.007 16.9 0.0 0.29 11.6 0.0 2.3 2 0 0 2 2 2 1 ABC transporter Dynamin_N PF00350.23 KSA03166.1 - 0.013 15.5 0.0 0.031 14.4 0.0 1.6 1 0 0 1 1 1 0 Dynamin family AAA_22 PF13401.6 KSA03166.1 - 0.076 13.3 0.0 0.51 10.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 KSA03166.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_28 PF13521.6 KSA03166.1 - 0.12 12.6 0.8 0.17 12.1 0.0 1.6 2 0 0 2 2 2 0 AAA domain AIG1 PF04548.16 KSA03166.1 - 0.12 11.6 0.1 0.25 10.6 0.1 1.4 1 0 0 1 1 1 0 AIG1 family AAA_16 PF13191.6 KSA03166.1 - 0.14 12.5 0.0 0.63 10.4 0.0 2.1 2 1 0 2 2 2 0 AAA ATPase domain MeaB PF03308.16 KSA03166.1 - 0.18 10.8 1.3 0.2 10.6 0.1 1.7 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Cg6151-P PF10233.9 KSA03167.1 - 5e-43 146.0 14.3 6.8e-43 145.6 14.3 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P Clc-like PF07062.12 KSA03167.1 - 0.025 14.1 8.6 0.04 13.4 7.6 1.7 1 1 0 1 1 1 0 Clc-like COPI_assoc PF08507.10 KSA03167.1 - 0.32 11.0 13.9 0.4 10.7 13.2 1.5 1 1 0 1 1 1 0 COPI associated protein DUF5592 PF17332.2 KSA03167.1 - 0.82 10.3 8.1 0.063 13.8 2.3 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5592) zf-CCHC PF00098.23 KSA03168.1 - 0.00013 21.9 37.3 0.0019 18.2 4.3 5.0 5 0 0 5 5 5 4 Zinc knuckle zf-C2H2_10 PF16588.5 KSA03168.1 - 0.022 14.5 4.1 0.022 14.5 4.1 3.0 2 0 0 2 2 2 0 C2H2 zinc-finger DUF4358 PF14270.6 KSA03168.1 - 0.058 13.7 1.9 0.17 12.2 1.9 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4358) Ferric_reduct PF01794.19 KSA03169.1 - 1.7e-15 57.3 11.7 5.6e-15 55.6 10.5 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KSA03169.1 - 0.0093 16.1 2.2 1 9.5 2.2 2.9 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KSA03169.1 - 0.051 13.7 0.0 0.18 11.9 0.0 1.9 1 0 0 1 1 1 0 FAD-binding domain FtsX PF02687.21 KSA03170.1 - 0.082 13.4 0.2 0.11 13.0 0.2 1.1 1 0 0 1 1 1 0 FtsX-like permease family PCI PF01399.27 KSA03172.1 - 0.00012 22.6 0.0 0.00073 20.0 0.0 2.4 2 1 0 2 2 2 1 PCI domain Smg4_UPF3 PF03467.15 KSA03173.1 - 1.6e-19 70.6 34.9 1.5e-17 64.2 34.7 3.0 1 1 0 1 1 1 1 Smg-4/UPF3 family BRAP2 PF07576.12 KSA03173.1 - 0.019 15.2 0.0 0.049 13.9 0.0 1.7 1 0 0 1 1 1 0 BRCA1-associated protein 2 DUF1987 PF09345.10 KSA03174.1 - 0.041 13.6 4.3 0.22 11.2 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1987) tRNA_int_end_N2 PF12928.7 KSA03175.1 - 1e-20 73.6 0.0 1.7e-20 73.0 0.0 1.3 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.14 KSA03175.1 - 0.0012 18.4 0.0 0.0026 17.4 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain Sgf11 PF08209.11 KSA03176.1 - 1.8e-15 56.2 2.2 2.6e-15 55.7 2.2 1.3 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) zf-CpG_bind_C PF12269.8 KSA03176.1 - 0.0003 20.7 0.4 0.0003 20.6 0.4 1.0 1 0 0 1 1 1 1 CpG binding protein zinc finger C terminal domain zf-C2HC_2 PF13913.6 KSA03176.1 - 0.0074 16.2 0.7 0.014 15.3 0.7 1.5 1 1 0 1 1 1 1 zinc-finger of a C2HC-type AMP-binding PF00501.28 KSA03177.1 - 9.6e-66 222.1 0.0 4.1e-65 220.0 0.0 1.7 2 0 0 2 2 2 1 AMP-binding enzyme Thioredoxin_13 PF18401.1 KSA03177.1 - 0.12 12.3 0.1 0.29 11.0 0.1 1.6 1 0 0 1 1 1 0 Thioredoxin-like domain PQ-loop PF04193.14 KSA03178.1 - 4.3e-40 135.3 23.2 1e-22 79.6 2.0 3.0 3 0 0 3 3 3 2 PQ loop repeat Zn_clus PF00172.18 KSA03179.1 - 2.9e-07 30.5 10.4 6.9e-07 29.3 10.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KSA03179.1 - 4.6e-05 22.6 0.3 0.00015 20.9 0.3 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KSA03180.1 - 3.6e-08 33.4 11.2 6.5e-08 32.6 11.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KSA03180.1 - 7.4e-06 25.2 0.1 5.2e-05 22.4 0.1 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain FAM196 PF15265.6 KSA03180.1 - 0.012 15.2 0.3 0.012 15.2 0.3 1.4 2 0 0 2 2 2 0 FAM196 family Zn_clus PF00172.18 KSA03182.1 - 1.5e-08 34.6 9.8 3.2e-08 33.5 9.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KSA03182.1 - 4.1e-08 32.6 0.4 5.2e-07 29.0 0.4 2.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Anticodon_1 PF08264.13 KSA03182.1 - 0.13 12.2 0.4 0.41 10.6 0.0 1.9 2 0 0 2 2 2 0 Anticodon-binding domain of tRNA DUF4195 PF13836.6 KSA03182.1 - 3.7 7.6 6.9 0.2 11.8 0.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4195) tRNA_m1G_MT PF01746.21 KSA03183.1 - 5.1e-29 101.4 0.1 5.1e-29 101.4 0.1 1.6 2 0 0 2 2 2 1 tRNA (Guanine-1)-methyltransferase Ras PF00071.22 KSA03184.1 - 8.2e-56 188.1 0.0 9.5e-56 187.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KSA03184.1 - 5.3e-22 78.3 0.0 1.1e-21 77.3 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KSA03184.1 - 4.1e-08 32.9 0.0 6.8e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KSA03184.1 - 0.0011 18.6 0.0 0.003 17.1 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KSA03184.1 - 0.0051 16.3 0.0 0.011 15.2 0.0 1.6 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 KSA03184.1 - 0.017 15.1 0.1 0.046 13.6 0.0 1.8 2 1 0 2 2 2 0 RsgA GTPase Gtr1_RagA PF04670.12 KSA03184.1 - 0.02 14.2 0.0 0.029 13.7 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Mito_fiss_Elm1 PF06258.11 KSA03184.1 - 0.046 12.8 0.0 0.067 12.3 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial fission ELM1 LAGLIDADG_WhiA PF14527.6 KSA03184.1 - 0.16 12.1 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 WhiA LAGLIDADG-like domain zf-CHCC PF10276.9 KSA03185.1 - 1.4e-14 53.8 0.5 2.8e-14 52.9 0.5 1.5 1 0 0 1 1 1 1 Zinc-finger domain zf_C2H2_6 PF18450.1 KSA03185.1 - 0.076 12.7 0.5 0.52 10.1 0.1 2.3 2 0 0 2 2 2 0 Zinc Finger domain LrgB PF04172.16 KSA03186.1 - 7.2e-50 169.5 3.5 7.2e-50 169.5 3.5 2.2 2 0 0 2 2 2 1 LrgB-like family LrgA PF03788.14 KSA03186.1 - 0.0013 18.7 4.6 0.0013 18.7 4.6 3.7 3 1 0 3 3 3 1 LrgA family RNase_H2-Ydr279 PF09468.10 KSA03187.1 - 2.6e-28 99.2 1.6 2.6e-28 99.2 1.6 1.7 2 0 0 2 2 2 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 KSA03187.1 - 2.2e-11 43.8 0.1 5e-11 42.7 0.1 1.6 1 0 0 1 1 1 1 Ydr279p protein triple barrel domain CelD_N PF02927.14 KSA03187.1 - 0.046 14.6 0.4 3.7 8.5 0.3 2.5 2 0 0 2 2 2 0 Cellulase N-terminal ig-like domain Band_7 PF01145.25 KSA03188.1 - 4.3e-32 111.6 0.1 7.2e-32 110.8 0.1 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_C PF16200.5 KSA03188.1 - 8.3e-26 89.8 0.2 1.9e-25 88.7 0.2 1.7 1 0 0 1 1 1 1 C-terminal region of band_7 Band_7_1 PF13421.6 KSA03188.1 - 0.0075 16.0 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 SPFH domain-Band 7 family Pox_A11 PF05061.13 KSA03188.1 - 0.014 14.7 0.7 0.028 13.7 0.4 1.8 2 0 0 2 2 2 0 Poxvirus A11 Protein Cys_rich_CPCC PF14206.6 KSA03188.1 - 0.17 11.7 0.0 0.4 10.5 0.0 1.5 1 0 0 1 1 1 0 Cysteine-rich CPCC RNase_PH PF01138.21 KSA03189.1 - 3.7e-20 72.8 0.0 5.6e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KSA03189.1 - 2.1e-10 40.5 0.1 4.3e-10 39.5 0.1 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Gly_transf_sug PF04488.15 KSA03190.1 - 4.2e-22 78.6 0.0 7.2e-22 77.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif DUF3698 PF12479.8 KSA03191.1 - 1e-38 132.1 0.0 1.1e-36 125.6 0.0 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF3698) Pkinase PF00069.25 KSA03191.1 - 3e-06 26.8 0.2 4.8e-06 26.1 0.2 1.3 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KSA03191.1 - 0.0025 17.2 0.1 0.0046 16.3 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KSA03191.1 - 0.035 14.0 0.0 0.098 12.6 0.0 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Acyltransferase PF01553.21 KSA03192.1 - 9.7e-16 57.6 0.0 2.4e-15 56.3 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase 2-oxogl_dehyd_N PF16078.5 KSA03192.1 - 0.11 12.1 0.0 0.43 10.2 0.0 2.0 1 0 0 1 1 1 0 2-oxoglutarate dehydrogenase N-terminus Pkinase PF00069.25 KSA03193.1 - 6e-36 124.2 7.1 1.4e-21 77.0 0.0 4.3 2 1 1 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KSA03193.1 - 2.7e-12 46.5 0.2 0.0014 18.0 0.0 4.1 4 0 0 4 4 4 3 Protein tyrosine kinase Kdo PF06293.14 KSA03193.1 - 0.0023 17.3 0.0 0.004 16.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pro_isomerase PF00160.21 KSA03194.1 - 3.6e-22 79.3 1.0 9.1e-22 78.0 0.2 1.8 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SRX PF09201.10 KSA03194.1 - 2.9 7.7 9.1 2.2 8.1 1.4 3.3 1 1 1 2 2 2 0 SRX, signal recognition particle receptor alpha subunit Adaptin_N PF01602.20 KSA03195.1 - 5.6e-116 388.2 13.0 6.7e-116 387.9 13.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 KSA03195.1 - 3.3e-17 62.8 0.4 7.1e-17 61.7 0.4 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 KSA03195.1 - 7.2e-05 22.9 9.9 0.00041 20.4 0.0 3.8 3 2 2 5 5 5 2 non-SMC mitotic condensation complex subunit 1 EntA_Immun PF08951.10 KSA03195.1 - 0.011 16.1 7.6 0.38 11.2 0.6 4.3 4 0 0 4 4 4 0 Enterocin A Immunity BDV_P24 PF06595.11 KSA03195.1 - 0.027 14.3 0.0 1.2 8.9 0.0 2.5 2 0 0 2 2 2 0 Borna disease virus P24 protein HEAT_2 PF13646.6 KSA03195.1 - 0.064 13.7 2.7 2.6 8.5 0.1 4.2 5 1 1 6 6 6 0 HEAT repeats ComR_TPR PF18710.1 KSA03195.1 - 0.096 12.2 5.7 0.13 11.8 0.4 3.4 3 1 1 4 4 4 0 ComR tetratricopeptide TB2_DP1_HVA22 PF03134.19 KSA03196.1 - 1.7e-26 91.9 4.6 2.5e-26 91.4 4.6 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family SURF6 PF04935.12 KSA03197.1 - 2.5e-44 151.5 47.8 2.5e-44 151.5 47.8 3.1 1 1 1 2 2 2 1 Surfeit locus protein 6 RRP14 PF15459.6 KSA03197.1 - 3.3e-14 53.2 2.9 3.3e-14 53.2 2.9 7.6 5 3 2 7 7 7 1 60S ribosome biogenesis protein Rrp14 V-ATPase_C PF03223.15 KSA03198.1 - 1.7e-112 376.5 6.9 1.9e-112 376.4 6.9 1.0 1 0 0 1 1 1 1 V-ATPase subunit C PCI PF01399.27 KSA03199.1 - 3.6e-08 33.9 1.1 3.6e-08 33.9 1.1 2.4 3 0 0 3 3 3 1 PCI domain DUF1638 PF07796.11 KSA03199.1 - 0.092 12.8 1.0 0.25 11.4 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1638) DUF4709 PF15821.5 KSA03199.1 - 0.14 12.5 3.1 0.38 11.0 0.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4709) FeoC PF09012.10 KSA03199.1 - 0.22 11.6 0.6 0.82 9.8 0.1 2.1 2 0 0 2 2 2 0 FeoC like transcriptional regulator Maelstrom PF13017.6 KSA03199.1 - 1.7 8.2 7.9 0.96 9.1 0.2 2.9 2 1 1 3 3 3 0 piRNA pathway germ-plasm component KELK PF15796.5 KSA03200.1 - 0.00031 21.1 9.5 0.00031 21.1 9.5 7.4 5 2 3 9 9 9 1 KELK-motif containing domain of MRCK Ser/Thr protein kinase DAGK_cat PF00781.24 KSA03201.1 - 9.1e-26 89.9 0.0 1.4e-25 89.3 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain MFS_1 PF07690.16 KSA03202.1 - 5.8e-25 88.0 35.4 2.8e-21 75.8 6.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily BolA PF01722.18 KSA03203.1 - 1.6e-19 70.0 0.2 4e-19 68.7 0.2 1.6 1 1 0 1 1 1 1 BolA-like protein RhoGAP PF00620.27 KSA03204.1 - 2e-35 121.9 0.3 5.6e-35 120.4 0.3 1.8 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 KSA03204.1 - 7.7e-30 102.9 44.0 5.7e-11 42.5 6.9 4.5 4 0 0 4 4 4 4 LIM domain Cnd1_N PF12922.7 KSA03204.1 - 0.17 11.7 4.9 0.56 10.0 0.0 3.4 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1, N-term zf-RING_7 PF02591.15 KSA03204.1 - 0.9 9.8 10.6 0.5 10.6 3.2 3.6 3 0 0 3 3 3 0 C4-type zinc ribbon domain PIG-H PF10181.9 KSA03205.1 - 7.3e-23 80.2 1.0 1e-22 79.8 0.1 1.8 2 0 0 2 2 2 1 GPI-GlcNAc transferase complex, PIG-H component Myb_DNA-bind_7 PF15963.5 KSA03206.1 - 3e-27 94.3 2.2 3e-27 94.3 2.2 2.6 2 1 1 3 3 3 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 KSA03206.1 - 5.6e-10 39.3 0.0 1.5e-09 37.9 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain K_oxygenase PF13434.6 KSA03206.1 - 0.058 12.5 0.6 0.13 11.3 0.1 1.9 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) WD40 PF00400.32 KSA03207.1 - 7.4e-12 45.6 7.5 1.7e-06 28.6 0.3 4.9 4 1 0 4 4 4 2 WD domain, G-beta repeat CDC45 PF02724.14 KSA03207.1 - 2.1e-05 23.1 3.5 3.1e-05 22.5 3.5 1.1 1 0 0 1 1 1 1 CDC45-like protein ANAPC4_WD40 PF12894.7 KSA03207.1 - 0.0003 21.0 0.0 0.0041 17.4 0.0 2.4 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 KSA03207.1 - 0.026 13.3 0.1 0.12 11.1 0.1 2.1 2 1 0 2 2 2 0 Nup133 N terminal like WD40_like PF17005.5 KSA03207.1 - 0.032 13.6 1.6 0.68 9.2 0.3 2.3 1 1 1 2 2 2 0 WD40-like domain GAGA_bind PF06217.12 KSA03207.1 - 0.33 11.2 11.2 0.52 10.6 11.2 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family PPL5 PF18168.1 KSA03207.1 - 1.1 8.4 6.4 1.8 7.8 6.4 1.3 1 0 0 1 1 1 0 Prim-pol family 5 RNA_pol_Rpc4 PF05132.14 KSA03207.1 - 4.4 7.7 9.8 7.6 7.0 9.8 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 His_Phos_1 PF00300.22 KSA03208.1 - 9.2e-08 32.0 0.5 4.8e-07 29.7 0.5 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) PRP1_N PF06424.12 KSA03208.1 - 0.032 14.7 0.5 0.079 13.4 0.5 1.6 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal Hist_deacetyl PF00850.19 KSA03209.1 - 2e-90 303.4 0.0 2.9e-90 302.9 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.9 KSA03209.1 - 5.2e-57 192.9 0.1 5.6e-48 163.3 0.1 2.7 1 1 1 2 2 2 2 Arb2 domain RhlB PF12300.8 KSA03209.1 - 1.1 9.4 4.7 2.1 8.4 4.7 1.4 1 0 0 1 1 1 0 ATP-dependent RNA helicase RhlB Pkinase PF00069.25 KSA03210.1 - 9.6e-40 136.6 0.0 1.8e-39 135.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KSA03210.1 - 8.7e-23 80.9 0.0 2.3e-22 79.5 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Seadorna_VP7 PF07387.11 KSA03210.1 - 0.12 11.4 0.4 0.28 10.2 0.1 1.8 2 0 0 2 2 2 0 Seadornavirus VP7 Methyltr_RsmB-F PF01189.17 KSA03211.1 - 2e-20 73.3 0.0 4.4e-20 72.2 0.0 1.7 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 KSA03211.1 - 0.064 13.8 0.0 0.32 11.5 0.0 2.3 1 1 0 1 1 1 0 N-terminal domain of 16S rRNA methyltransferase RsmF Iso_dh PF00180.20 KSA03212.1 - 4e-103 345.2 0.1 7e-103 344.4 0.1 1.3 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase GrpE PF01025.19 KSA03213.1 - 1.2e-51 174.7 8.9 1.7e-51 174.2 8.9 1.3 1 1 0 1 1 1 1 GrpE Clusterin PF01093.17 KSA03213.1 - 0.011 14.9 3.1 0.013 14.5 3.1 1.2 1 0 0 1 1 1 0 Clusterin FAM184 PF15665.5 KSA03213.1 - 0.023 14.5 11.1 0.036 13.9 11.1 1.3 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B PTR PF12789.7 KSA03213.1 - 0.12 12.5 0.3 0.29 11.2 0.3 1.7 1 0 0 1 1 1 0 Phage tail repeat like V_ATPase_I PF01496.19 KSA03213.1 - 0.16 9.9 3.9 0.16 9.8 3.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1664 PF07889.12 KSA03213.1 - 0.23 11.5 3.5 2.7 8.0 0.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Prominin PF05478.11 KSA03213.1 - 0.58 8.0 3.7 0.71 7.8 3.7 1.0 1 0 0 1 1 1 0 Prominin ADIP PF11559.8 KSA03213.1 - 1.8 8.6 11.7 1.8 8.6 10.4 1.6 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF3391 PF11871.8 KSA03213.1 - 2.1 8.9 6.9 4.1 7.9 6.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) CLZ PF16526.5 KSA03213.1 - 7.4 7.0 8.9 8.7 6.8 3.5 2.6 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels OPT PF03169.15 KSA03214.1 - 1.3e-187 625.2 56.0 1.5e-187 625.0 56.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein CcmD PF04995.14 KSA03214.1 - 0.61 10.2 0.0 0.61 10.2 0.0 2.7 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) Fcf1 PF04900.12 KSA03215.1 - 4.1e-34 116.9 0.1 8.5e-34 115.9 0.1 1.5 1 0 0 1 1 1 1 Fcf1 Presenilin PF01080.17 KSA03215.1 - 7.8 5.1 5.6 10 4.7 5.6 1.1 1 0 0 1 1 1 0 Presenilin R3H PF01424.22 KSA03216.1 - 5.4e-10 39.1 0.0 1.1e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.17 KSA03216.1 - 4.6e-05 23.4 8.5 4.6e-05 23.4 8.5 11.9 14 1 0 14 14 14 2 NF-X1 type zinc finger Pkinase PF00069.25 KSA03217.1 - 5e-71 239.1 0.2 1.9e-70 237.2 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KSA03217.1 - 1.6e-41 142.3 0.0 2.8e-41 141.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KSA03217.1 - 2.5e-09 36.8 0.0 6.6e-09 35.5 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KSA03217.1 - 0.0025 17.8 0.0 0.0043 17.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KSA03217.1 - 0.0027 17.1 0.1 0.0052 16.2 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KSA03217.1 - 1.2 8.7 5.7 0.3 10.7 0.6 2.3 2 0 0 2 2 2 0 RIO1 family Rad51 PF08423.11 KSA03218.1 - 5.2e-130 432.2 0.0 6.2e-130 432.0 0.0 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 KSA03218.1 - 3.1e-09 36.7 0.0 4.5e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein ATPase PF06745.13 KSA03218.1 - 4.4e-07 29.5 0.2 1.1e-06 28.2 0.2 1.7 1 1 0 1 1 1 1 KaiC AAA_25 PF13481.6 KSA03218.1 - 3.7e-06 26.7 0.0 5.4e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.6 KSA03218.1 - 7.3e-06 26.5 1.0 1.6e-05 25.4 1.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain DnaB_C PF03796.15 KSA03218.1 - 0.00089 18.7 0.1 0.0086 15.4 0.0 2.0 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain PAXNEB PF05625.11 KSA03218.1 - 0.02 14.1 0.2 0.13 11.4 0.1 2.0 2 0 0 2 2 2 0 PAXNEB protein ACT_6 PF13740.6 KSA03218.1 - 0.14 12.1 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 ACT domain ssDNA_TraI_N PF18272.1 KSA03218.1 - 0.15 12.1 0.2 0.38 10.8 0.2 1.6 1 0 0 1 1 1 0 single-stranded DNA binding TraI N-terminal subdomain Fungal_trans PF04082.18 KSA03219.1 - 1.2e-17 63.9 1.2 2.6e-17 62.8 1.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KSA03219.1 - 5.4e-08 32.8 10.1 9e-08 32.1 10.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Diphtheria_C PF02763.14 KSA03219.1 - 0.096 12.3 0.2 2.2 7.9 0.0 2.4 2 0 0 2 2 2 0 Diphtheria toxin, C domain Snapin_Pallidin PF14712.6 KSA03219.1 - 1.1 9.8 4.4 2.9 8.4 2.9 2.3 2 0 0 2 2 2 0 Snapin/Pallidin AhpC-TSA PF00578.21 KSA03220.1 - 2.8e-31 108.0 0.0 3.9e-31 107.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.9 KSA03220.1 - 3.9e-13 49.0 0.1 7.5e-13 48.1 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.10 KSA03220.1 - 4.8e-12 45.8 0.0 6.3e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 Redoxin tRNA_bind PF01588.20 KSA03221.1 - 1.2e-09 38.2 0.1 1.7e-09 37.6 0.1 1.3 1 0 0 1 1 1 1 Putative tRNA binding domain MCM PF00493.23 KSA03222.1 - 4.1e-101 336.8 0.6 6e-101 336.2 0.6 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KSA03222.1 - 2.5e-38 130.8 0.1 4.9e-38 129.8 0.1 1.5 1 0 0 1 1 1 1 MCM OB domain MCM6_C PF18263.1 KSA03222.1 - 6.5e-32 110.0 1.2 1.6e-31 108.8 1.2 1.7 1 0 0 1 1 1 1 MCM6 C-terminal winged-helix domain MCM_lid PF17855.1 KSA03222.1 - 5.6e-26 90.8 1.0 5.6e-26 90.8 1.0 2.0 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 KSA03222.1 - 3.7e-23 82.1 0.3 1.4e-22 80.2 0.3 2.1 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KSA03222.1 - 5.7e-06 25.9 0.0 1.7e-05 24.3 0.0 1.8 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KSA03222.1 - 0.012 15.5 0.0 0.046 13.6 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KSA03222.1 - 0.015 15.0 0.0 0.031 14.0 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain zf-C2H2 PF00096.26 KSA03223.1 - 0.0003 21.1 0.1 0.0003 21.1 0.1 4.0 4 0 0 4 4 4 1 Zinc finger, C2H2 type zf-C2HE PF16278.5 KSA03223.1 - 0.068 13.6 0.5 0.46 11.0 0.5 2.6 1 1 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_4 PF13894.6 KSA03223.1 - 0.078 13.9 0.2 0.078 13.9 0.2 4.1 4 0 0 4 4 4 0 C2H2-type zinc finger zf-met PF12874.7 KSA03223.1 - 0.085 13.3 3.2 0.25 11.8 0.4 3.0 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KSA03223.1 - 0.41 11.0 6.0 0.34 11.3 0.6 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 KSA03223.1 - 0.83 10.0 4.1 0.59 10.5 0.8 2.3 2 1 1 3 3 3 0 C2H2-type zinc ribbon GAGA PF09237.11 KSA03223.1 - 0.95 9.3 4.4 3.3 7.6 0.1 3.3 3 0 0 3 3 3 0 GAGA factor GST_N_2 PF13409.6 KSA03224.1 - 1.7e-23 82.7 0.0 3.7e-23 81.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KSA03224.1 - 1.7e-10 40.7 0.0 3.8e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KSA03224.1 - 2.5e-05 24.4 0.0 6.3e-05 23.1 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KSA03224.1 - 0.00071 19.7 0.1 0.0018 18.4 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KSA03224.1 - 0.03 14.7 0.0 6 7.4 0.0 2.4 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Ras PF00071.22 KSA03225.1 - 4.5e-24 84.9 0.6 6.5e-24 84.4 0.0 1.5 2 0 0 2 2 2 1 Ras family GTP_EFTU PF00009.27 KSA03225.1 - 0.027 14.0 0.9 0.05 13.1 0.0 1.7 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain Roc PF08477.13 KSA03225.1 - 0.03 14.5 0.5 0.15 12.3 0.0 2.2 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase SPATIAL PF15256.6 KSA03225.1 - 0.032 14.6 1.8 0.045 14.1 1.8 1.2 1 0 0 1 1 1 0 SPATIAL EssA PF10661.9 KSA03225.1 - 0.25 11.2 7.0 0.34 10.7 7.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA Presenilin PF01080.17 KSA03225.1 - 6.3 5.4 10.3 8 5.1 10.3 1.1 1 0 0 1 1 1 0 Presenilin PRC2_HTH_1 PF18118.1 KSA03225.1 - 6.9 7.5 11.3 26 5.7 11.3 1.8 1 1 0 1 1 1 0 Polycomb repressive complex 2 tri-helical domain Pyridox_oxase_2 PF12766.7 KSA03226.1 - 1.7e-28 99.2 0.1 3.3e-28 98.2 0.1 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Putative_PNPOx PF01243.20 KSA03226.1 - 2.9e-09 37.0 0.0 5.5e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Atrophin-1 PF03154.15 KSA03226.1 - 0.0014 17.1 2.1 0.0018 16.7 2.1 1.0 1 0 0 1 1 1 1 Atrophin-1 family Linker_histone PF00538.19 KSA03227.1 - 1.1e-24 86.5 0.1 1.1e-24 86.5 0.1 2.6 2 1 0 2 2 2 1 linker histone H1 and H5 family HC2 PF07382.11 KSA03227.1 - 0.63 10.1 74.2 0.95 9.5 74.2 1.3 1 0 0 1 1 1 0 Histone H1-like nucleoprotein HC2 DHFR_1 PF00186.19 KSA03228.1 - 1.2e-29 103.0 0.0 1.5e-29 102.7 0.0 1.1 1 0 0 1 1 1 1 Dihydrofolate reductase DSPc PF00782.20 KSA03229.1 - 2.8e-13 49.9 3.3 1.1e-12 47.9 0.1 3.0 2 1 0 2 2 2 1 Dual specificity phosphatase, catalytic domain WG_beta_rep PF14903.6 KSA03229.1 - 0.18 12.1 0.5 0.72 10.2 0.1 2.3 2 0 0 2 2 2 0 WG containing repeat YEATS PF03366.16 KSA03231.1 - 5.1e-20 71.2 0.0 9.8e-20 70.3 0.0 1.5 1 0 0 1 1 1 1 YEATS family BET PF17035.5 KSA03231.1 - 2.2e-07 30.9 0.9 4.7e-07 29.9 0.9 1.5 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation Neurokinin_B PF03823.14 KSA03231.1 - 0.15 12.1 0.2 0.53 10.3 0.0 1.8 2 0 0 2 2 2 0 Neurokinin B WD40 PF00400.32 KSA03232.1 - 6.6e-33 112.2 22.8 7.9e-06 26.5 0.3 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KSA03232.1 - 5.1e-10 39.5 0.5 0.096 13.0 0.3 5.3 3 3 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain TRF PF08558.10 KSA03233.1 - 8e-94 313.7 0.0 1.4e-93 313.0 0.0 1.4 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.31 KSA03233.1 - 2.9e-06 27.4 1.5 1.4e-05 25.2 1.5 2.2 1 1 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KSA03233.1 - 0.014 15.7 1.7 0.019 15.2 0.2 2.0 2 0 0 2 2 2 0 Myb-like DNA-binding domain Aminotran_3 PF00202.21 KSA03234.1 - 1.8e-99 333.2 0.0 2.2e-99 332.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Mito_carr PF00153.27 KSA03235.1 - 6e-64 212.0 2.5 3.3e-22 78.2 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein B12D PF06522.11 KSA03236.1 - 2.4e-06 27.2 0.1 3.3e-06 26.8 0.1 1.3 1 1 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit Transcrip_reg PF01709.20 KSA03237.1 - 1.2e-69 234.4 2.4 1.3e-69 234.2 2.4 1.0 1 0 0 1 1 1 1 Transcriptional regulator CBM9_1 PF06452.11 KSA03237.1 - 0.065 13.1 3.0 3.8 7.4 0.2 2.2 2 0 0 2 2 2 0 Carbohydrate family 9 binding domain-like ATP-synt_F PF01990.17 KSA03238.1 - 3.4e-31 107.4 0.1 4e-31 107.2 0.1 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit fn3_2 PF16893.5 KSA03239.1 - 5.1e-38 129.1 0.3 1.1e-37 128.1 0.3 1.6 1 0 0 1 1 1 1 Fibronectin type III domain CHS5_N PF16892.5 KSA03239.1 - 1.5e-24 85.7 0.1 2.5e-24 85.0 0.1 1.4 1 0 0 1 1 1 1 Chitin biosynthesis protein CHS5 N-terminus BRCT PF00533.26 KSA03239.1 - 3.3e-12 46.6 0.1 1.1e-11 45.0 0.1 2.0 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KSA03239.1 - 7.8e-07 29.0 0.0 1.5e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain DUF3006 PF11213.8 KSA03239.1 - 0.007 16.6 0.1 0.007 16.6 0.1 3.2 3 1 0 3 3 3 1 Protein of unknown function (DUF3006) Sds3 PF08598.11 KSA03240.1 - 3.3e-49 167.8 0.3 3.3e-49 167.8 0.3 2.9 2 1 0 2 2 2 1 Sds3-like RGS_DHEX PF18148.1 KSA03240.1 - 0.37 10.9 0.1 0.37 10.9 0.1 2.8 2 1 0 2 2 2 0 Regulator of G-protein signalling DHEX domain RRM_1 PF00076.22 KSA03241.1 - 3.5e-12 45.9 7.0 7.4e-08 32.1 0.1 3.9 3 1 1 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HNF-1B_C PF04812.13 KSA03241.1 - 0.53 10.1 5.4 0.2 11.5 1.2 2.0 2 0 0 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), beta isoform C terminus COG4 PF08318.12 KSA03242.1 - 1.6e-90 303.6 1.0 3.6e-90 302.4 1.0 1.6 1 0 0 1 1 1 1 COG4 transport protein MGDG_synth PF06925.11 KSA03242.1 - 3.5 7.7 6.1 18 5.4 1.0 3.6 2 1 1 3 3 3 0 Monogalactosyldiacylglycerol (MGDG) synthase zf-CCCH PF00642.24 KSA03243.1 - 3.2e-14 52.4 29.4 0.0016 18.3 1.1 5.8 5 1 0 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KSA03243.1 - 1.2e-13 50.6 40.6 2e-05 24.5 3.9 5.6 6 0 0 6 6 6 5 Zinc finger domain Torus PF16131.5 KSA03243.1 - 4.4e-10 40.2 20.7 0.0095 16.6 1.1 4.9 1 1 4 5 5 5 4 Torus domain zf-CCCH_3 PF15663.5 KSA03243.1 - 3.7e-09 36.8 13.2 6.5e-07 29.5 6.7 2.3 1 1 1 2 2 2 2 Zinc-finger containing family zf-CCCH_4 PF18044.1 KSA03243.1 - 2.6e-05 23.9 4.6 0.0016 18.2 0.9 4.8 5 0 0 5 5 5 3 CCCH-type zinc finger Spo7 PF03907.13 KSA03244.1 - 5.5e-66 222.2 2.8 1e-65 221.4 2.8 1.4 1 0 0 1 1 1 1 Spo7-like protein GWT1 PF06423.12 KSA03245.1 - 4.2e-37 127.6 7.0 4.2e-37 127.6 7.0 2.6 3 0 0 3 3 3 1 GWT1 Oxysterol_BP PF01237.18 KSA03246.1 - 2.7e-62 210.8 2.5 3.3e-60 203.9 2.5 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein STELLO PF03385.17 KSA03246.1 - 0.049 12.4 0.1 0.33 9.7 0.1 1.9 2 0 0 2 2 2 0 STELLO glycosyltransferases DUF1923 PF09083.10 KSA03246.1 - 0.21 11.3 1.3 2.6 7.8 0.2 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF1923) Ribosomal_L35Ae PF01247.18 KSA03247.1 - 4.8e-41 138.8 1.4 5.4e-41 138.7 1.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 KSA03247.1 - 0.089 13.0 0.0 3.2 8.1 0.0 2.1 2 0 0 2 2 2 0 RimM N-terminal domain GRAB PF10375.9 KSA03248.1 - 1.3e-05 24.9 1.9 1.3e-05 24.9 1.9 2.1 2 0 0 2 2 2 1 GRIP-related Arf-binding domain Spc7 PF08317.11 KSA03248.1 - 0.0016 17.4 18.2 0.0016 17.4 18.2 4.1 1 1 3 4 4 4 2 Spc7 kinetochore protein HMMR_N PF15905.5 KSA03248.1 - 0.0025 17.3 29.3 0.0025 17.3 29.3 4.0 1 1 3 4 4 4 2 Hyaluronan mediated motility receptor N-terminal ATG16 PF08614.11 KSA03248.1 - 0.0027 18.0 20.8 0.0027 18.0 20.8 4.8 2 1 3 5 5 5 2 Autophagy protein 16 (ATG16) HAUS-augmin3 PF14932.6 KSA03248.1 - 0.0028 17.3 10.5 0.0028 17.3 10.5 4.9 1 1 4 5 5 5 2 HAUS augmin-like complex subunit 3 ADIP PF11559.8 KSA03248.1 - 0.0036 17.4 5.1 0.0036 17.4 5.1 6.9 1 1 6 7 7 5 2 Afadin- and alpha -actinin-Binding ZapB PF06005.12 KSA03248.1 - 0.0063 16.9 7.9 0.0063 16.9 7.9 8.2 4 2 2 6 6 3 1 Cell division protein ZapB APG6_N PF17675.1 KSA03248.1 - 0.73 10.4 82.1 0.13 12.8 22.4 5.0 1 1 3 4 4 4 0 Apg6 coiled-coil region FAM76 PF16046.5 KSA03248.1 - 0.73 9.1 68.0 1 8.6 21.6 3.8 1 1 3 4 4 4 0 FAM76 protein DUF1664 PF07889.12 KSA03248.1 - 2.4 8.2 46.4 1.2 9.1 4.9 5.4 1 1 5 6 6 6 0 Protein of unknown function (DUF1664) Yuri_gagarin PF15934.5 KSA03248.1 - 3.1 7.6 49.4 0.12 12.2 9.6 4.0 1 1 3 4 4 4 0 Yuri gagarin DUF3584 PF12128.8 KSA03248.1 - 5.4 4.4 65.6 1.2 6.6 11.1 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) RFC1 PF08519.12 KSA03249.1 - 3.7e-58 196.1 0.2 9.8e-58 194.8 0.0 1.8 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain AAA PF00004.29 KSA03249.1 - 7.4e-11 42.6 0.0 2.7e-10 40.8 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BRCT PF00533.26 KSA03249.1 - 1.7e-09 37.9 0.0 4.5e-09 36.6 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Rad17 PF03215.15 KSA03249.1 - 4.2e-08 33.3 0.0 1.2e-07 31.9 0.0 1.7 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 KSA03249.1 - 0.00045 20.6 0.3 0.003 18.0 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KSA03249.1 - 0.00067 19.4 0.0 0.0017 18.1 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KSA03249.1 - 0.0075 16.6 0.0 0.028 14.7 0.0 2.0 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KSA03249.1 - 0.012 15.9 0.1 0.39 11.1 0.0 2.8 2 1 0 2 2 2 0 RNA helicase AAA_assoc_2 PF16193.5 KSA03249.1 - 0.017 15.4 0.0 0.081 13.3 0.0 2.2 1 0 0 1 1 1 0 AAA C-terminal domain AAA_5 PF07728.14 KSA03249.1 - 0.027 14.5 0.2 1.2 9.1 0.0 3.0 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) DNA_pol3_delta PF06144.13 KSA03249.1 - 0.031 14.1 0.0 0.13 12.0 0.0 2.1 2 0 0 2 2 2 0 DNA polymerase III, delta subunit AAA_14 PF13173.6 KSA03249.1 - 0.086 12.9 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KSA03249.1 - 0.098 13.2 0.0 0.098 13.2 0.0 2.4 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.6 KSA03249.1 - 0.52 10.5 0.0 0.52 10.5 0.0 2.3 3 0 0 3 3 1 0 AAA domain Pkinase PF00069.25 KSA03250.1 - 2.9e-67 226.8 0.0 4.4e-67 226.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KSA03250.1 - 6.4e-35 120.7 0.0 9.2e-35 120.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KSA03250.1 - 8.9e-08 31.8 0.0 2.5e-07 30.3 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KSA03250.1 - 0.00041 19.2 0.0 0.00072 18.4 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 KSA03250.1 - 0.00079 18.6 0.0 0.0012 18.0 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.14 KSA03250.1 - 0.0035 16.7 0.0 0.0067 15.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KSA03250.1 - 0.011 15.7 0.0 0.017 15.1 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 KSA03250.1 - 0.014 15.1 0.0 0.081 12.5 0.0 2.0 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 KSA03250.1 - 0.045 12.7 0.0 0.088 11.7 0.0 1.4 1 1 0 1 1 1 0 Haspin like kinase domain MFS_1 PF07690.16 KSA03251.1 - 2.9e-30 105.4 20.2 3.9e-30 105.0 20.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 KSA03251.1 - 4.5 5.4 14.0 0.72 8.1 5.7 2.6 1 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family G_glu_transpept PF01019.21 KSA03252.1 - 5.4e-120 401.6 0.0 6.2e-120 401.4 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Fungal_trans PF04082.18 KSA03253.1 - 3e-06 26.5 6.0 5.6e-06 25.6 6.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain MWFE PF15879.5 KSA03254.1 - 1.6e-21 76.2 0.1 2.3e-21 75.7 0.1 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase MWFE subunit Nop53 PF07767.11 KSA03255.1 - 1.6e-76 258.3 44.4 1.8e-76 258.1 44.4 1.0 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) MGDG_synth PF06925.11 KSA03256.1 - 0.24 11.5 2.9 0.15 12.2 0.5 1.9 2 0 0 2 2 2 0 Monogalactosyldiacylglycerol (MGDG) synthase Nfu_N PF08712.11 KSA03257.1 - 1.7e-29 101.7 0.0 3.8e-29 100.6 0.0 1.6 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 KSA03257.1 - 9.9e-28 96.1 0.0 1.6e-27 95.4 0.0 1.3 1 0 0 1 1 1 1 NifU-like domain SNF2_N PF00176.23 KSA03258.1 - 5e-56 189.9 0.1 8.8e-56 189.1 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KSA03258.1 - 1e-18 67.7 0.0 6.3e-18 65.1 0.2 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KSA03258.1 - 1.1e-10 41.7 1.9 2.2e-09 37.5 0.0 3.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DIOX_N PF14226.6 KSA03258.1 - 0.32 11.8 5.8 5.2 7.9 0.1 2.6 2 0 0 2 2 2 0 non-haem dioxygenase in morphine synthesis N-terminal ERG4_ERG24 PF01222.17 KSA03259.1 - 1.6e-149 498.4 12.3 1.8e-149 498.2 12.3 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 KSA03259.1 - 1.9e-05 24.3 0.8 1.9e-05 24.3 0.8 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) RCC1 PF00415.18 KSA03260.1 - 3.9e-26 91.4 10.0 3.1e-05 24.5 0.0 6.3 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KSA03260.1 - 3.9e-22 77.5 22.5 6.1e-09 35.5 0.1 6.5 6 1 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat DUF775 PF05603.12 KSA03261.1 - 4e-64 215.8 0.2 4.5e-64 215.7 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) Cys_Met_Meta_PP PF01053.20 KSA03262.1 - 1e-139 465.3 0.2 1.2e-139 465.2 0.2 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KSA03262.1 - 4.9e-05 22.7 0.0 8.3e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KSA03262.1 - 7e-05 22.3 0.1 0.0018 17.7 0.0 2.4 2 1 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 KSA03262.1 - 0.019 13.9 0.2 0.064 12.2 0.1 1.8 1 1 0 2 2 2 0 Aminotransferase class-V SIL1 PF16782.5 KSA03263.1 - 7.5e-86 287.9 12.3 7.5e-86 287.9 12.3 1.5 2 0 0 2 2 2 1 Nucleotide exchange factor SIL1 W2 PF02020.18 KSA03263.1 - 0.018 15.2 0.3 0.046 13.9 0.3 1.7 1 0 0 1 1 1 0 eIF4-gamma/eIF5/eIF2-epsilon Hydrolase_6 PF13344.6 KSA03263.1 - 0.025 14.7 0.2 3.3 7.9 0.0 2.9 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Histidinol_dh PF00815.20 KSA03263.1 - 0.098 11.6 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Histidinol dehydrogenase GSH_synth_ATP PF03917.17 KSA03264.1 - 1.9e-134 448.2 0.1 2.2e-134 448.0 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 KSA03264.1 - 4.5e-34 117.0 0.2 1.5e-33 115.3 0.2 1.9 2 0 0 2 2 2 1 Eukaryotic glutathione synthase EI24 PF07264.11 KSA03265.1 - 7.3e-09 36.1 10.9 9.9e-09 35.7 10.9 1.1 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) WD40 PF00400.32 KSA03266.1 - 3.5e-11 43.5 1.8 0.0064 17.3 0.0 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KSA03266.1 - 4.4e-10 39.7 0.0 1.3 9.4 0.0 5.7 2 2 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KSA03266.1 - 0.022 14.7 0.4 21 5.2 0.1 3.4 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat KCH PF16944.5 KSA03268.1 - 1.8e-80 270.4 28.3 2.3e-80 270.0 28.3 1.1 1 0 0 1 1 1 1 Fungal potassium channel KleE PF17394.2 KSA03268.1 - 9.4 6.5 11.4 1.1 9.5 4.5 2.5 2 0 0 2 2 2 0 Uncharacterized KleE stable inheritance protein PRCC PF10253.9 KSA03269.1 - 0.081 13.7 10.1 0.11 13.3 10.1 1.1 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting DUF3453 PF11935.8 KSA03270.1 - 6.8e-47 160.0 4.8 4.8e-46 157.2 2.7 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF3453) DSPc PF00782.20 KSA03271.1 - 5.4e-24 84.5 0.1 1e-18 67.5 0.0 3.5 2 1 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KSA03271.1 - 7.6e-05 22.4 0.0 0.00015 21.4 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Rep_fac_C PF08542.11 KSA03273.1 - 4.4e-18 65.5 1.3 8.5e-18 64.6 0.6 1.9 2 0 0 2 2 1 1 Replication factor C C-terminal domain AAA PF00004.29 KSA03273.1 - 1.7e-15 57.6 0.0 4.6e-15 56.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 KSA03273.1 - 4.7e-14 52.5 1.2 5.1e-12 45.9 0.0 3.5 3 1 0 3 3 3 1 DNA polymerase III, delta subunit Rad17 PF03215.15 KSA03273.1 - 2.1e-08 34.3 0.0 4.5e-08 33.2 0.0 1.7 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 KSA03273.1 - 7.9e-06 26.2 0.6 0.00018 21.8 0.0 3.0 2 2 1 3 3 3 1 AAA domain AAA_11 PF13086.6 KSA03273.1 - 1.2e-05 25.3 1.0 2.2e-05 24.4 0.5 1.9 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KSA03273.1 - 4.9e-05 23.1 0.0 0.0002 21.2 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KSA03273.1 - 8.4e-05 23.0 0.1 0.0025 18.2 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain ResIII PF04851.15 KSA03273.1 - 0.00022 21.3 0.4 0.0022 18.0 0.0 2.5 2 2 0 2 2 2 1 Type III restriction enzyme, res subunit Mg_chelatase PF01078.21 KSA03273.1 - 0.00028 20.3 0.0 0.007 15.8 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_assoc_2 PF16193.5 KSA03273.1 - 0.00045 20.5 2.6 0.00067 19.9 0.7 2.2 1 1 1 2 2 2 1 AAA C-terminal domain DUF815 PF05673.13 KSA03273.1 - 0.00096 18.4 0.0 0.0021 17.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) ABC_tran PF00005.27 KSA03273.1 - 0.00097 19.7 0.1 1.1 9.8 0.0 2.6 2 0 0 2 2 2 1 ABC transporter AAA_30 PF13604.6 KSA03273.1 - 0.0021 17.8 0.0 0.031 14.0 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.6 KSA03273.1 - 0.0024 17.6 0.0 0.0079 15.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KSA03273.1 - 0.0045 17.0 0.0 0.031 14.3 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 KSA03273.1 - 0.0047 17.5 0.7 0.013 16.0 0.7 1.9 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KSA03273.1 - 0.0063 16.0 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_19 PF13245.6 KSA03273.1 - 0.0081 16.5 0.1 0.075 13.4 0.0 2.4 2 1 0 2 2 1 1 AAA domain AAA_18 PF13238.6 KSA03273.1 - 0.0093 16.5 1.2 0.12 12.9 1.2 2.8 1 1 0 1 1 1 1 AAA domain DNA_pol3_gamma3 PF12169.8 KSA03273.1 - 0.018 15.0 1.6 0.063 13.2 0.1 2.6 3 1 0 4 4 4 0 DNA polymerase III subunits gamma and tau domain III ATPase_2 PF01637.18 KSA03273.1 - 0.019 14.9 0.9 0.96 9.3 0.0 2.6 1 1 2 3 3 3 0 ATPase domain predominantly from Archaea DUF2075 PF09848.9 KSA03273.1 - 0.036 13.3 0.0 0.11 11.7 0.0 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.6 KSA03273.1 - 0.047 14.1 0.6 0.62 10.5 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA_3 PF07726.11 KSA03273.1 - 0.047 13.6 0.0 0.66 9.8 0.0 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Utp13 PF08625.11 KSA03273.1 - 0.06 13.2 0.3 0.12 12.3 0.3 1.5 1 0 0 1 1 1 0 Utp13 specific WD40 associated domain RNA_helicase PF00910.22 KSA03273.1 - 0.063 13.7 0.0 0.31 11.4 0.0 2.2 2 0 0 2 2 2 0 RNA helicase AAA_28 PF13521.6 KSA03273.1 - 0.095 12.9 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sec3_C_2 PF15278.6 KSA03273.1 - 0.1 12.9 2.5 0.15 12.4 0.2 2.5 3 1 0 3 3 2 0 Sec3 exocyst complex subunit BTB_2 PF02214.22 KSA03274.1 - 0.09 13.1 0.0 0.29 11.5 0.0 1.8 2 0 0 2 2 2 0 BTB/POZ domain Yae1_N PF09811.9 KSA03275.1 - 1.5e-11 43.8 0.0 2.1e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 Essential protein Yae1, N terminal DUF2680 PF10925.8 KSA03277.1 - 0.024 14.6 0.0 0.056 13.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2680) DUF4932 PF16286.5 KSA03277.1 - 0.078 12.2 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4932) PX PF00787.24 KSA03277.1 - 0.094 12.7 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 PX domain Inositol_P PF00459.25 KSA03278.1 - 1e-73 248.2 0.0 1.2e-73 248.0 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family DUF728 PF05304.12 KSA03278.1 - 0.11 12.3 1.4 0.35 10.7 0.2 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF728) AP_endonuc_2 PF01261.24 KSA03279.1 - 5.4e-37 127.3 0.0 8.8e-37 126.6 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel PAP2 PF01569.21 KSA03280.1 - 1.3e-24 86.5 0.6 1.3e-24 86.5 0.6 1.5 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 KSA03280.1 - 0.058 13.1 7.6 0.018 14.7 2.1 2.6 2 1 0 2 2 2 0 PAP2 superfamily DUF5510 PF17629.2 KSA03280.1 - 4.5 7.3 9.7 7.2 6.6 2.9 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5510) Choline_kinase PF01633.20 KSA03281.1 - 4.8e-44 150.5 0.9 1e-43 149.4 0.1 1.8 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 KSA03281.1 - 5e-05 23.3 0.0 0.00014 21.9 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family HNF-1_N PF04814.13 KSA03281.1 - 0.21 12.2 2.0 2 9.0 0.0 2.7 2 1 1 3 3 3 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus HGTP_anticodon2 PF12745.7 KSA03282.1 - 1.2e-88 297.0 10.6 1.2e-88 297.0 10.6 2.4 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs Pkinase PF00069.25 KSA03282.1 - 1.4e-66 224.6 6.1 4.3e-37 127.9 0.0 4.7 5 0 0 5 5 5 4 Protein kinase domain Pkinase_Tyr PF07714.17 KSA03282.1 - 1.1e-39 136.3 0.0 9.7e-19 67.6 0.0 4.3 4 0 0 4 4 4 4 Protein tyrosine kinase RWD PF05773.22 KSA03282.1 - 7.4e-14 52.0 0.9 7.4e-14 52.0 0.9 3.0 3 0 0 3 3 3 1 RWD domain tRNA-synt_His PF13393.6 KSA03282.1 - 3.7e-08 33.0 0.0 8.1e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 Histidyl-tRNA synthetase Kinase-like PF14531.6 KSA03282.1 - 0.0023 17.3 2.1 0.11 11.8 0.0 3.2 4 0 0 4 4 4 1 Kinase-like APH PF01636.23 KSA03282.1 - 0.041 13.8 0.1 0.099 12.5 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 KSA03282.1 - 0.056 12.8 0.0 0.75 9.1 0.0 2.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Mre11_DNA_bind PF04152.14 KSA03283.1 - 5.1e-48 163.6 1.5 5.1e-48 163.6 1.5 2.2 3 0 0 3 3 3 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 KSA03283.1 - 3.1e-12 47.4 1.1 3.1e-12 47.4 1.1 2.0 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KSA03283.1 - 0.0065 16.7 0.0 0.083 13.1 0.0 2.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain ATP11 PF06644.11 KSA03284.1 - 1.2e-87 294.2 3.8 1.3e-87 294.0 3.8 1.0 1 0 0 1 1 1 1 ATP11 protein DUF5001 PF16392.5 KSA03284.1 - 0.061 13.2 0.1 0.18 11.7 0.1 1.8 1 0 0 1 1 1 0 Ig-like domain zf-DNL PF05180.12 KSA03285.1 - 2.8e-31 107.3 1.1 4.4e-31 106.6 1.1 1.3 1 0 0 1 1 1 1 DNL zinc finger HypA PF01155.19 KSA03285.1 - 0.055 13.5 0.1 0.081 13.0 0.1 1.3 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TFIIS_C PF01096.18 KSA03285.1 - 0.064 13.1 1.1 7.9 6.4 0.2 2.3 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zf-CSL PF05207.13 KSA03285.1 - 0.088 12.5 0.1 0.18 11.6 0.1 1.6 1 0 0 1 1 1 0 CSL zinc finger Zn_ribbon_SprT PF17283.2 KSA03285.1 - 0.21 11.6 2.2 4.7 7.2 0.1 2.3 2 0 0 2 2 2 0 SprT-like zinc ribbon domain zinc_ribbon_4 PF13717.6 KSA03285.1 - 0.25 11.3 4.2 1.7 8.7 0.1 2.4 1 1 1 2 2 2 0 zinc-ribbon domain zf-C3HC4_3 PF13920.6 KSA03286.1 - 2.3e-06 27.4 8.8 2.3e-06 27.4 8.8 3.6 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KSA03286.1 - 0.012 15.5 10.3 0.012 15.5 10.3 2.8 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) GPAT_N PF14829.6 KSA03286.1 - 0.12 12.4 0.0 0.34 10.9 0.0 1.7 1 0 0 1 1 1 0 Glycerol-3-phosphate acyltransferase N-terminal PGP_phosphatase PF09419.10 KSA03287.1 - 2.7e-73 245.1 0.0 3.2e-73 244.9 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 KSA03287.1 - 0.00023 21.2 0.0 0.00036 20.5 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like DUF3102 PF11300.8 KSA03287.1 - 0.15 12.3 0.1 0.34 11.1 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3102) FAT PF02259.23 KSA03288.1 - 1.1e-77 261.6 5.1 1.1e-77 261.6 5.1 2.5 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 KSA03288.1 - 2.3e-36 125.9 0.0 6.4e-36 124.4 0.0 1.9 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 KSA03288.1 - 2.3e-06 27.3 0.1 6.5e-06 25.9 0.1 1.8 1 0 0 1 1 1 1 FATC domain DUF3385 PF11865.8 KSA03288.1 - 0.038 13.9 0.4 0.3 11.0 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3385) RPN6_N PF18055.1 KSA03288.1 - 0.19 12.1 1.7 14 6.0 0.0 4.0 3 0 0 3 3 3 0 26S proteasome regulatory subunit RPN6 N-terminal domain SMYLE_N PF18615.1 KSA03289.1 - 1.4 8.4 8.2 0.17 11.4 2.4 2.0 2 0 0 2 2 2 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Fig1 PF12351.8 KSA03290.1 - 1.3e-52 178.5 5.7 1.3e-52 178.5 5.7 1.8 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.12 KSA03290.1 - 1.2e-06 28.3 13.1 1.6e-06 28.0 13.1 1.1 1 0 0 1 1 1 1 SUR7/PalI family MgtE PF01769.16 KSA03290.1 - 0.95 9.9 9.1 0.39 11.1 0.5 3.0 1 1 0 2 2 2 0 Divalent cation transporter SurA_N_3 PF13624.6 KSA03290.1 - 6.5 6.5 5.1 51 3.6 0.1 3.0 2 1 1 3 3 3 0 SurA N-terminal domain Acyltransferase PF01553.21 KSA03291.1 - 1.3e-22 79.9 0.0 2.5e-22 78.9 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 KSA03291.1 - 3.4e-09 36.6 1.3 9.7e-08 32.0 1.3 2.4 1 1 0 1 1 1 1 Acyltransferase C-terminus DUF4176 PF13780.6 KSA03291.1 - 0.13 12.3 0.0 0.35 10.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4176) MFS_1 PF07690.16 KSA03292.1 - 7.3e-36 123.8 24.3 7.3e-36 123.8 24.3 2.5 1 1 1 2 2 2 1 Major Facilitator Superfamily Exo84_C PF16528.5 KSA03293.1 - 7.2e-17 61.9 4.5 7.2e-17 61.9 4.5 2.6 2 1 0 2 2 2 1 Exocyst component 84 C-terminal Na_trans_cytopl PF11933.8 KSA03293.1 - 0.006 16.4 0.8 0.017 15.0 0.8 1.7 1 0 0 1 1 1 1 Cytoplasmic domain of voltage-gated Na+ ion channel Vps51 PF08700.11 KSA03293.1 - 0.0077 16.3 3.6 0.0077 16.3 3.6 2.8 4 0 0 4 4 4 1 Vps51/Vps67 CENP-H PF05837.12 KSA03293.1 - 0.69 10.3 6.8 2.7 8.4 6.8 2.0 1 0 0 1 1 1 0 Centromere protein H (CENP-H) APG6_N PF17675.1 KSA03293.1 - 0.72 10.4 16.7 0.24 11.9 10.1 2.7 3 0 0 3 3 3 0 Apg6 coiled-coil region TolA_bind_tri PF16331.5 KSA03293.1 - 1.7 8.8 11.1 0.75 9.9 3.3 2.8 2 0 0 2 2 2 0 TolA binding protein trimerisation COMMD1_N PF17221.3 KSA03293.1 - 2.4 8.5 7.6 2.4 8.5 0.7 3.4 3 1 1 4 4 4 0 COMMD1 N-terminal domain COG2 PF06148.11 KSA03293.1 - 3.4 7.8 7.2 0.77 9.9 3.0 2.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 WD40 PF00400.32 KSA03294.1 - 1.9e-13 50.7 9.9 0.00013 22.7 0.0 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat LisH PF08513.11 KSA03294.1 - 3.5e-09 36.3 0.8 9.5e-09 34.9 0.1 2.1 2 0 0 2 2 2 1 LisH ANAPC4_WD40 PF12894.7 KSA03294.1 - 5.8e-08 32.9 4.5 0.18 12.1 0.0 6.0 4 2 1 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KSA03294.1 - 0.0059 16.5 1.6 1 9.2 0.0 3.6 4 0 0 4 4 4 1 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 KSA03294.1 - 0.011 15.1 0.0 0.025 13.9 0.0 1.7 1 0 0 1 1 1 0 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.12 KSA03294.1 - 0.073 13.0 0.8 30 4.7 0.0 3.5 2 1 1 3 3 3 0 WD40-like Beta Propeller Repeat RAB3GAP2_N PF14655.6 KSA03294.1 - 0.077 12.2 0.1 0.65 9.2 0.0 2.6 2 1 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus UPF0139 PF03669.13 KSA03295.1 - 1.2e-05 25.0 0.0 2e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) SIP1 PF04938.12 KSA03296.1 - 3.9e-24 85.6 1.5 5.8e-24 85.0 1.5 1.2 1 0 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) DUF3072 PF11272.8 KSA03296.1 - 0.034 14.0 0.1 0.1 12.5 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3072) Tfb4 PF03850.14 KSA03297.1 - 4.9e-110 367.4 2.4 6e-110 367.1 2.4 1.1 1 0 0 1 1 1 1 Transcription factor Tfb4 DUF4776 PF16003.5 KSA03297.1 - 0.039 13.0 1.6 0.079 12.0 1.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) Rad50_zn_hook PF04423.14 KSA03297.1 - 0.069 13.0 0.1 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 Rad50 zinc hook motif MafB19-deam PF14437.6 KSA03298.1 - 1.1e-22 80.2 0.0 1.4e-22 79.9 0.0 1.0 1 0 0 1 1 1 1 MafB19-like deaminase dCMP_cyt_deam_1 PF00383.23 KSA03298.1 - 7.4e-22 77.1 0.0 9.9e-22 76.7 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.6 KSA03298.1 - 0.0011 19.0 0.5 0.0071 16.4 0.5 2.0 1 1 0 1 1 1 1 Bd3614-like deaminase SNAD4 PF18750.1 KSA03298.1 - 0.0017 18.4 0.0 0.0041 17.2 0.0 1.6 2 0 0 2 2 2 1 Secreted Novel AID/APOBEC-like Deaminase 4 NAD1 PF18778.1 KSA03298.1 - 0.0049 17.0 0.1 0.056 13.5 0.0 2.0 2 0 0 2 2 2 1 Novel AID APOBEC clade 1 APOBEC_N PF08210.11 KSA03298.1 - 0.006 16.5 0.6 0.48 10.3 0.1 2.1 1 1 1 2 2 2 1 APOBEC-like N-terminal domain APOBEC2 PF18772.1 KSA03298.1 - 0.0069 16.4 0.3 0.062 13.3 0.3 2.0 1 1 0 1 1 1 1 APOBEC2 NAD2 PF18782.1 KSA03298.1 - 0.0097 16.0 0.1 0.086 12.9 0.1 2.0 1 1 0 1 1 1 1 Novel AID APOBEC clade 2 APOBEC3 PF18771.1 KSA03298.1 - 0.036 14.2 0.0 0.065 13.4 0.0 1.4 1 0 0 1 1 1 0 APOBEC3 APOBEC4_like PF18774.1 KSA03298.1 - 0.15 12.0 0.0 0.21 11.5 0.0 1.4 1 1 0 1 1 1 0 APOBEC4-like -AID/APOBEC-deaminase Pkinase PF00069.25 KSA03299.1 - 4.2e-17 62.4 0.0 1.1e-16 61.1 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.32 KSA03299.1 - 7.7e-09 36.0 7.5 5.7e-05 23.8 0.3 4.5 3 0 0 3 3 3 2 WD domain, G-beta repeat Pkinase_Tyr PF07714.17 KSA03299.1 - 1.8e-05 24.2 0.0 3.6e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT PF02985.22 KSA03299.1 - 0.0063 16.7 0.0 0.43 11.0 0.0 3.8 3 0 0 3 3 3 1 HEAT repeat Hira PF07569.11 KSA03299.1 - 0.064 13.0 0.6 4.5 6.9 0.1 3.3 3 0 0 3 3 3 0 TUP1-like enhancer of split Sugar_tr PF00083.24 KSA03300.1 - 1.3e-85 288.0 26.1 1.6e-85 287.7 26.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KSA03300.1 - 8.5e-23 80.8 32.5 8.5e-23 80.8 32.5 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Ribosomal_S13_N PF08069.12 KSA03301.1 - 2.3e-29 101.2 0.1 4e-29 100.4 0.1 1.4 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 KSA03301.1 - 4.4e-15 55.7 0.4 6.2e-15 55.2 0.4 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 Cbl_N PF02262.16 KSA03302.1 - 0.031 14.3 0.0 0.032 14.2 0.0 1.1 1 0 0 1 1 1 0 CBL proto-oncogene N-terminal domain 1 DSPc PF00782.20 KSA03303.1 - 2.5e-22 79.1 0.0 6.2e-22 77.8 0.0 1.7 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain DSPn PF14671.6 KSA03303.1 - 1.4e-10 41.8 0.0 8.9e-10 39.2 0.0 2.2 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half Y_phosphatase PF00102.27 KSA03303.1 - 2.1e-05 24.2 0.0 3.9e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DUF3439 PF11921.8 KSA03303.1 - 0.055 13.4 1.1 0.26 11.2 0.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) PTPlike_phytase PF14566.6 KSA03303.1 - 0.07 13.2 0.0 0.19 11.9 0.0 1.7 1 0 0 1 1 1 0 Inositol hexakisphosphate CDKN3 PF05706.12 KSA03303.1 - 0.078 12.6 0.5 0.15 11.7 0.5 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) VWD PF00094.25 KSA03303.1 - 0.3 11.3 2.1 0.3 11.4 0.9 1.7 2 0 0 2 2 2 0 von Willebrand factor type D domain Complex1_LYR PF05347.15 KSA03305.1 - 0.011 15.8 2.3 3.6 7.7 0.0 3.3 3 0 0 3 3 3 0 Complex 1 protein (LYR family) IZUMO PF15005.6 KSA03305.1 - 1.6 9.3 5.9 0.35 11.4 0.3 2.6 2 1 0 3 3 3 0 Izumo sperm-egg fusion, Ig domain-associated RPAP2_Rtr1 PF04181.13 KSA03306.1 - 4.9e-24 84.5 1.6 7.6e-24 83.8 1.6 1.3 1 0 0 1 1 1 1 Rtr1/RPAP2 family PI_PP_C PF18365.1 KSA03306.1 - 0.046 13.7 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 Phosphoinositide phosphatase C-terminal domain DUF747 PF05346.11 KSA03307.1 - 3.8e-97 325.6 17.5 3.8e-97 325.6 17.5 1.7 2 0 0 2 2 2 1 Eukaryotic membrane protein family COX15-CtaA PF02628.15 KSA03308.1 - 2.2e-114 381.9 4.3 2.7e-114 381.6 4.3 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein AMP-binding PF00501.28 KSA03309.1 - 6.3e-57 193.0 0.0 8.3e-57 192.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KSA03309.1 - 4e-06 27.7 0.0 7.5e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain YejG PF13989.6 KSA03309.1 - 0.16 12.4 0.0 0.3 11.6 0.0 1.4 1 0 0 1 1 1 0 YejG-like protein PGK PF00162.19 KSA03310.1 - 3.6e-151 503.4 2.4 4.1e-151 503.2 2.4 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase Fes1 PF08609.10 KSA03311.1 - 1.3e-22 80.5 5.8 7.9e-22 78.0 2.5 2.9 3 0 0 3 3 3 1 Nucleotide exchange factor Fes1 SIL1 PF16782.5 KSA03311.1 - 5e-05 22.7 0.7 0.00017 20.9 0.3 1.9 1 1 1 2 2 2 1 Nucleotide exchange factor SIL1 Atx10homo_assoc PF09759.9 KSA03311.1 - 0.0068 16.4 1.4 0.027 14.5 0.0 2.7 3 2 0 3 3 3 1 Spinocerebellar ataxia type 10 protein domain DUF3361 PF11841.8 KSA03311.1 - 0.049 13.6 2.3 0.051 13.5 0.3 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF3361) DUF4393 PF14337.6 KSA03311.1 - 0.13 12.0 3.7 0.32 10.8 3.2 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4393) ERCC4 PF02732.15 KSA03312.1 - 7.5e-19 68.5 3.4 1.3e-18 67.7 3.4 1.4 1 0 0 1 1 1 1 ERCC4 domain SpoIIAA-like PF11964.8 KSA03312.1 - 0.036 15.1 0.0 0.14 13.2 0.0 2.1 1 1 0 1 1 1 0 SpoIIAA-like DUF963 PF06131.11 KSA03312.1 - 3.7 7.1 5.9 0.28 10.6 0.8 1.8 2 0 0 2 2 2 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) Sec8_exocyst PF04048.14 KSA03313.1 - 2.7e-54 182.9 3.7 2.7e-54 182.9 3.7 3.2 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain MGS PF02142.22 KSA03313.1 - 0.099 12.8 0.1 3.5 7.9 0.0 2.9 2 0 0 2 2 2 0 MGS-like domain Med19 PF10278.9 KSA03313.1 - 0.12 12.3 0.0 0.36 10.8 0.0 1.8 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 AHD PF17793.1 KSA03313.1 - 0.24 11.2 2.4 1.4 8.8 0.2 3.3 2 0 0 2 2 2 0 ANC1 homology domain (AHD) Cbl_N PF02262.16 KSA03313.1 - 0.54 10.3 6.6 0.14 12.2 0.4 2.9 3 0 0 3 3 3 0 CBL proto-oncogene N-terminal domain 1 DUF2556 PF10831.8 KSA03313.1 - 1.4 8.9 3.5 28 4.8 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2556) Ctr PF04145.15 KSA03314.1 - 6.7e-23 81.9 0.1 9.1e-23 81.5 0.1 1.2 1 0 0 1 1 1 1 Ctr copper transporter family ICAP-1_inte_bdg PF10480.9 KSA03314.1 - 0.042 13.9 0.3 0.068 13.2 0.3 1.3 1 0 0 1 1 1 0 Beta-1 integrin binding protein zf-Di19 PF05605.12 KSA03315.1 - 0.01 16.1 0.1 0.03 14.6 0.1 1.8 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.26 KSA03315.1 - 0.055 13.9 13.2 4.6 7.9 0.0 4.1 3 1 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KSA03315.1 - 0.29 12.1 10.5 9.6 7.4 0.0 4.1 4 0 0 4 4 4 0 C2H2-type zinc finger HIM1 PF08732.10 KSA03316.1 - 3.1e-09 36.6 0.0 4.4e-08 32.8 0.0 2.0 1 1 1 2 2 2 1 HIM1 NAD_binding_10 PF13460.6 KSA03316.1 - 6.7e-09 35.9 0.0 9.4e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KSA03316.1 - 5e-06 26.3 0.1 1e-05 25.3 0.1 1.5 1 1 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.24 KSA03316.1 - 3.5e-05 24.2 0.1 7.1e-05 23.2 0.0 1.5 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 KSA03316.1 - 8e-05 22.2 0.1 0.00015 21.3 0.1 1.4 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 KSA03316.1 - 0.049 13.7 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus zf-Di19 PF05605.12 KSA03317.1 - 0.026 14.8 2.9 0.069 13.4 0.1 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding OrfB_Zn_ribbon PF07282.11 KSA03317.1 - 0.16 11.9 2.2 0.16 11.9 0.4 1.9 2 0 0 2 2 2 0 Putative transposase DNA-binding domain YhfH PF14149.6 KSA03317.1 - 0.16 12.0 2.0 0.37 10.8 0.1 2.4 2 0 0 2 2 2 0 YhfH-like protein zf-C2H2 PF00096.26 KSA03317.1 - 0.48 11.0 13.6 7.9 7.2 0.0 4.0 3 1 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KSA03317.1 - 1.6 9.8 11.9 11 7.2 0.3 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger zf-TRAF PF02176.18 KSA03317.1 - 9.1 7.1 8.5 5.3 7.8 2.9 2.4 2 0 0 2 2 2 0 TRAF-type zinc finger Ribosomal_L15e PF00827.17 KSA03318.1 - 8.2e-89 296.4 10.4 1e-88 296.1 10.4 1.0 1 0 0 1 1 1 1 Ribosomal L15 AICARFT_IMPCHas PF01808.18 KSA03319.1 - 2.8e-92 309.3 0.0 4e-92 308.8 0.0 1.2 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 KSA03319.1 - 4.6e-25 87.6 0.0 1.3e-24 86.2 0.0 1.8 1 0 0 1 1 1 1 MGS-like domain DnaJ PF00226.31 KSA03320.1 - 4.5e-16 58.7 0.2 1.2e-15 57.4 0.2 1.7 1 0 0 1 1 1 1 DnaJ domain Sec63 PF02889.16 KSA03320.1 - 0.025 13.7 0.0 0.05 12.8 0.0 1.6 1 0 0 1 1 1 0 Sec63 Brl domain Acetyltransf_1 PF00583.25 KSA03322.1 - 2.9e-11 43.6 0.0 3.5e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KSA03322.1 - 4.2e-10 39.7 0.1 1.4e-09 37.9 0.1 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KSA03322.1 - 7.1e-10 39.2 0.0 9.6e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KSA03322.1 - 0.00022 21.1 0.0 0.00038 20.4 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_15 PF17013.5 KSA03322.1 - 0.0084 15.6 0.2 0.01 15.3 0.2 1.3 1 0 0 1 1 1 1 Putative acetyl-transferase Acetyltransf_4 PF13420.7 KSA03322.1 - 0.014 15.5 0.1 0.026 14.7 0.1 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Nudix_hydro PF18290.1 KSA03322.1 - 0.08 13.0 0.1 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 Nudix hydrolase domain Cyt-b5 PF00173.28 KSA03323.1 - 2.9e-12 46.6 0.0 3.4e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain RRM_9 PF18444.1 KSA03324.1 - 1.2e-27 95.5 0.0 4.1e-27 93.8 0.0 2.0 1 0 0 1 1 1 1 RNA recognition motif TAP_C PF03943.13 KSA03324.1 - 2.2e-11 43.2 0.1 2.2e-11 43.2 0.1 2.0 2 0 0 2 2 2 1 TAP C-terminal domain NTF2 PF02136.20 KSA03324.1 - 0.00038 21.0 3.2 0.23 12.0 1.4 3.4 3 1 0 3 3 3 2 Nuclear transport factor 2 (NTF2) domain LRR_4 PF12799.7 KSA03324.1 - 0.62 10.6 14.1 0.044 14.2 7.3 2.8 2 1 2 4 4 4 0 Leucine Rich repeats (2 copies) Glycos_transf_1 PF00534.20 KSA03325.1 - 2.6e-28 98.7 0.0 3.9e-28 98.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KSA03325.1 - 1.5e-23 83.7 0.1 2.3e-23 83.1 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KSA03325.1 - 1.4e-08 34.9 0.0 2.3e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 PIGA PF08288.12 KSA03325.1 - 6.1e-05 23.5 0.5 0.00017 22.1 0.1 2.0 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glyco_trans_1_2 PF13524.6 KSA03325.1 - 0.0024 18.2 0.0 0.0045 17.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 CAP_GLY PF01302.25 KSA03326.1 - 2.9e-20 72.0 0.2 4.8e-20 71.3 0.2 1.3 1 0 0 1 1 1 1 CAP-Gly domain Spc7 PF08317.11 KSA03326.1 - 0.0044 16.0 8.8 0.0044 16.0 8.8 5.1 2 1 3 5 5 5 3 Spc7 kinetochore protein FUSC PF04632.12 KSA03326.1 - 0.2 10.1 3.9 0.094 11.2 0.4 2.1 3 0 0 3 3 3 0 Fusaric acid resistance protein family DUF4407 PF14362.6 KSA03326.1 - 0.24 10.7 34.1 0.15 11.4 5.3 3.5 2 1 0 3 3 3 0 Domain of unknown function (DUF4407) DUF1664 PF07889.12 KSA03326.1 - 2.3 8.3 41.9 1.6 8.8 2.0 6.5 3 1 3 6 6 6 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 KSA03326.1 - 2.5 8.4 20.1 4.6 7.6 0.2 5.4 4 2 0 5 5 5 0 Bacterial protein of unknown function (DUF948) MbeD_MobD PF04899.12 KSA03326.1 - 3.5 7.8 10.5 2.9 8.0 1.1 3.8 3 0 0 3 3 3 0 MbeD/MobD like Filament PF00038.21 KSA03326.1 - 7.1 6.1 71.2 0.4 10.2 10.8 4.5 2 2 1 3 3 3 0 Intermediate filament protein EF-hand_7 PF13499.6 KSA03327.1 - 1.4e-21 76.7 11.3 1.4e-10 41.5 1.3 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KSA03327.1 - 6.9e-20 69.0 10.7 1.4e-07 30.6 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 KSA03327.1 - 3e-16 57.9 9.5 6.2e-07 28.8 0.1 4.3 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 KSA03327.1 - 9.1e-16 57.5 12.4 2.3e-06 27.3 0.5 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 KSA03327.1 - 4e-08 32.4 3.0 0.0025 17.2 0.0 3.6 3 0 0 3 3 3 3 EF hand EF-hand_4 PF12763.7 KSA03327.1 - 6.1e-05 22.9 0.5 0.0084 16.0 0.0 2.3 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 KSA03327.1 - 0.0022 18.0 0.3 0.34 10.8 0.0 3.2 1 1 3 4 4 4 1 Caleosin related protein EF-hand_9 PF14658.6 KSA03327.1 - 0.0043 17.3 0.3 0.34 11.3 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain HTH_40 PF14493.6 KSA03327.1 - 0.05 14.1 0.1 0.81 10.2 0.0 2.2 1 1 1 2 2 2 0 Helix-turn-helix domain SPARC_Ca_bdg PF10591.9 KSA03327.1 - 0.083 13.2 1.1 0.21 11.9 0.2 1.9 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF1002 PF06207.11 KSA03327.1 - 0.16 11.4 0.2 10 5.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1002) MgtE_N PF03448.17 KSA03327.1 - 0.18 12.4 2.2 0.53 10.9 0.1 2.3 3 0 0 3 3 3 0 MgtE intracellular N domain PRP9_N PF16958.5 KSA03328.1 - 0.19 11.8 7.8 0.18 11.8 3.8 2.4 2 0 0 2 2 2 0 Pre-mRNA-splicing factor PRP9 N-terminus AAA PF00004.29 KSA03329.1 - 5.3e-43 146.6 0.0 8.8e-43 145.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KSA03329.1 - 2.1e-10 40.2 0.0 4.1e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 KSA03329.1 - 1.7e-08 34.3 0.0 3.3e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 KSA03329.1 - 3.5e-08 34.0 0.9 4.2e-05 24.0 0.1 3.1 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 KSA03329.1 - 9.7e-07 28.9 0.1 1.4e-05 25.1 0.1 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KSA03329.1 - 3.7e-06 27.2 0.0 6.8e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) TsaE PF02367.17 KSA03329.1 - 4.8e-05 23.3 0.0 8.6e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RuvB_N PF05496.12 KSA03329.1 - 5.1e-05 23.1 0.0 0.0001 22.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KSA03329.1 - 0.00051 20.3 0.2 0.023 15.0 0.1 2.3 1 1 1 2 2 2 1 AAA domain TIP49 PF06068.13 KSA03329.1 - 0.0017 17.6 0.1 0.003 16.8 0.1 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain RNA_helicase PF00910.22 KSA03329.1 - 0.0028 18.0 0.0 0.0066 16.8 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_18 PF13238.6 KSA03329.1 - 0.0031 18.0 0.0 0.011 16.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KSA03329.1 - 0.0042 16.5 0.1 0.0093 15.4 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KSA03329.1 - 0.0051 16.6 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 KSA03329.1 - 0.0059 16.8 0.0 0.015 15.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain DUF4200 PF13863.6 KSA03329.1 - 0.0069 16.8 0.6 0.018 15.4 0.6 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4200) ATPase PF06745.13 KSA03329.1 - 0.0094 15.3 0.7 0.042 13.2 0.1 2.3 3 0 0 3 3 3 1 KaiC AAA_7 PF12775.7 KSA03329.1 - 0.012 15.1 0.0 0.028 13.9 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 KSA03329.1 - 0.013 15.2 0.0 0.025 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KSA03329.1 - 0.023 14.7 0.0 0.045 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KSA03329.1 - 0.025 14.8 0.0 0.057 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KSA03329.1 - 0.038 13.4 0.2 0.07 12.6 0.2 1.3 1 0 0 1 1 1 0 PhoH-like protein Sigma54_activat PF00158.26 KSA03329.1 - 0.052 13.3 0.1 0.19 11.4 0.1 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.17 KSA03329.1 - 0.091 11.8 0.1 0.16 11.0 0.1 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_3 PF07726.11 KSA03329.1 - 0.099 12.5 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 KSA03329.1 - 0.1 12.9 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KSA03329.1 - 0.11 12.1 1.2 0.22 11.1 0.2 1.9 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 KSA03329.1 - 0.15 11.9 0.6 0.59 9.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KSA03329.1 - 0.16 11.7 0.1 0.32 10.7 0.1 1.4 1 0 0 1 1 1 0 AAA domain NTP_transf_3 PF12804.7 KSA03330.1 - 1.1e-06 29.1 0.0 2.4e-06 28.0 0.0 1.5 1 1 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.23 KSA03330.1 - 1.2e-06 28.2 0.0 2.8e-06 27.1 0.0 1.6 1 1 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 KSA03330.1 - 3e-05 23.6 5.6 0.018 14.8 1.8 3.2 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) DUF4954 PF16314.5 KSA03330.1 - 0.0018 16.5 1.8 0.0039 15.4 1.8 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4954) CTP_transf_3 PF02348.19 KSA03330.1 - 0.0022 17.9 0.0 0.0043 17.0 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase Hexapep_2 PF14602.6 KSA03330.1 - 1.2 8.9 12.2 22 4.9 5.7 3.3 1 1 1 2 2 2 0 Hexapeptide repeat of succinyl-transferase DUF4588 PF15251.6 KSA03331.1 - 2e-24 86.8 2.5 8.9e-24 84.6 2.5 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4588) Carn_acyltransf PF00755.20 KSA03331.1 - 0.0019 16.9 0.0 0.003 16.2 0.0 1.3 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Longin PF13774.6 KSA03332.1 - 6.3e-23 80.6 0.0 1.1e-22 79.8 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 KSA03332.1 - 3.3e-15 55.6 0.0 5.3e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 Synaptobrevin DUF1664 PF07889.12 KSA03332.1 - 0.0064 16.5 0.6 0.0095 16.0 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) PSD4 PF07631.11 KSA03332.1 - 0.096 13.2 0.4 0.13 12.8 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1592) Mon1 PF03164.14 KSA03333.1 - 5.1e-122 407.8 12.7 7.5e-122 407.3 12.7 1.3 1 0 0 1 1 1 1 Trafficking protein Mon1 DUF3038 PF11237.8 KSA03333.1 - 0.053 13.6 0.4 1.4 9.0 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3038) RRF PF01765.19 KSA03334.1 - 1.7e-42 145.1 2.1 1.7e-42 145.1 2.1 1.5 2 0 0 2 2 2 1 Ribosome recycling factor Ribosomal_L18p PF00861.22 KSA03334.1 - 0.041 14.3 0.1 0.13 12.6 0.1 1.8 1 0 0 1 1 1 0 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast ART-PolyVal PF18760.1 KSA03334.1 - 0.053 14.6 2.6 0.088 13.8 0.2 2.2 2 0 0 2 2 2 0 ADP-Ribosyltransferase in polyvalent proteins DUF5600 PF18150.1 KSA03334.1 - 0.057 14.0 0.8 1.3 9.7 0.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5600) Ipi1_N PF12333.8 KSA03335.1 - 1.1e-26 93.4 1.8 1.1e-26 93.4 1.8 2.4 2 0 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation Brr6_like_C_C PF10104.9 KSA03336.1 - 1.8e-42 144.3 2.6 3e-42 143.5 2.6 1.4 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain MFS_1 PF07690.16 KSA03337.1 - 1e-34 120.0 43.7 1e-34 120.0 43.7 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Gaa1 PF04114.14 KSA03337.1 - 0.089 11.8 1.1 3.6 6.5 0.2 2.4 2 1 0 2 2 2 0 Gaa1-like, GPI transamidase component GATA PF00320.27 KSA03338.1 - 0.17 11.5 5.5 0.45 10.2 0.2 2.5 2 0 0 2 2 2 0 GATA zinc finger tRNA-synt_1b PF00579.25 KSA03339.1 - 5.5e-72 242.6 0.0 7.4e-72 242.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) CK_II_beta PF01214.18 KSA03340.1 - 8.8e-73 244.0 0.0 1.1e-72 243.6 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Hira PF07569.11 KSA03341.1 - 3.5e-80 268.9 0.1 3.4e-79 265.7 0.0 2.6 3 0 0 3 3 3 1 TUP1-like enhancer of split ANAPC4_WD40 PF12894.7 KSA03341.1 - 5.8e-15 55.4 0.1 3.3e-07 30.5 0.0 5.2 3 2 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KSA03341.1 - 5.7e-11 42.8 8.7 1.9 9.5 0.2 8.0 8 0 0 8 8 8 2 WD domain, G-beta repeat HIRA_B PF09453.10 KSA03341.1 - 6.8e-09 35.4 1.4 1.6e-08 34.2 1.4 1.7 1 0 0 1 1 1 1 HIRA B motif PD40 PF07676.12 KSA03341.1 - 0.00079 19.3 0.6 2.7 8.1 0.1 3.8 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KSA03341.1 - 0.0011 18.0 0.2 2.4 7.0 0.0 4.0 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein CCSAP PF15748.5 KSA03341.1 - 5.4 7.1 7.7 12 6.0 7.7 1.5 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated FAD_binding_6 PF00970.24 KSA03342.1 - 6.2e-06 26.5 0.0 4.5e-05 23.7 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KSA03342.1 - 0.001 19.7 0.0 1.4 9.6 0.0 2.4 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain WD40 PF00400.32 KSA03343.1 - 1.2e-32 111.3 19.6 5.2e-07 30.3 0.1 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KSA03343.1 - 5.3e-11 42.7 4.3 0.048 14.0 0.2 5.1 4 2 2 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Syntaxin_2 PF14523.6 KSA03344.1 - 1.1e-11 44.9 11.8 1.1e-11 44.9 11.8 2.5 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.19 KSA03344.1 - 6.4e-10 38.9 1.6 1.1e-09 38.1 0.0 2.4 3 0 0 3 3 3 1 SNARE domain MCPsignal PF00015.21 KSA03344.1 - 0.0045 16.8 1.7 0.02 14.7 0.7 2.2 2 0 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Synaptobrevin PF00957.21 KSA03344.1 - 0.074 12.9 3.4 0.17 11.7 0.0 2.9 3 0 0 3 3 3 0 Synaptobrevin DUF1664 PF07889.12 KSA03344.1 - 0.11 12.5 12.6 0.15 12.1 4.8 2.8 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Syntaxin PF00804.25 KSA03344.1 - 0.18 11.5 15.4 0.47 10.1 15.4 1.7 1 1 0 1 1 1 0 Syntaxin HicB-like_2 PF15970.5 KSA03344.1 - 0.24 11.5 1.4 2.4 8.4 0.0 2.7 3 0 0 3 3 3 0 HicB_like antitoxin of bacterial toxin-antitoxin system SLATT_5 PF18160.1 KSA03344.1 - 0.29 10.4 9.2 1.9 7.8 6.5 2.6 2 1 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 LMBR1 PF04791.16 KSA03344.1 - 0.29 10.0 4.8 0.4 9.5 4.8 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Syntaxin-6_N PF09177.11 KSA03344.1 - 0.31 11.6 10.9 2.2 8.9 4.0 3.1 2 1 1 3 3 3 0 Syntaxin 6, N-terminal Peptidase_S46 PF10459.9 KSA03344.1 - 0.45 9.1 7.6 0.55 8.8 7.6 1.0 1 0 0 1 1 1 0 Peptidase S46 GLE1 PF07817.13 KSA03344.1 - 1.1 8.4 8.9 2.9 7.0 0.5 2.5 2 1 0 2 2 2 0 GLE1-like protein DUF4446 PF14584.6 KSA03344.1 - 8.2 6.4 13.1 0.22 11.5 1.0 3.4 1 1 2 4 4 4 0 Protein of unknown function (DUF4446) Pyr_redox_2 PF07992.14 KSA03345.1 - 1.4e-51 175.5 0.0 1.6e-51 175.3 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KSA03345.1 - 5.5e-19 68.5 0.0 4.3e-16 59.2 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KSA03345.1 - 1.5e-18 67.1 0.0 2.9e-17 62.9 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KSA03345.1 - 5.8e-06 25.6 0.4 0.36 9.9 0.0 3.9 3 1 0 4 4 4 2 Glucose inhibited division protein A NAD_binding_8 PF13450.6 KSA03345.1 - 8.7e-05 22.7 0.0 0.01 16.1 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KSA03345.1 - 0.00012 21.3 0.1 0.29 10.2 0.0 3.1 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.6 KSA03345.1 - 0.001 19.5 0.0 0.18 12.3 0.0 2.4 2 1 0 2 2 2 1 Putative NAD(P)-binding Thi4 PF01946.17 KSA03345.1 - 0.0041 16.4 0.0 0.014 14.6 0.0 1.8 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 KSA03345.1 - 0.0082 15.4 0.0 1.7 7.8 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain FAD_binding_2 PF00890.24 KSA03345.1 - 0.013 14.6 1.2 6.4 5.7 0.1 3.3 2 2 2 4 4 4 0 FAD binding domain DAO PF01266.24 KSA03345.1 - 0.035 13.7 0.2 13 5.2 0.0 3.0 2 1 0 3 3 3 0 FAD dependent oxidoreductase HI0933_like PF03486.14 KSA03345.1 - 0.062 12.0 0.1 3.2 6.3 0.1 2.7 3 0 0 3 3 3 0 HI0933-like protein Shikimate_DH PF01488.20 KSA03345.1 - 0.11 12.5 0.0 21 5.2 0.0 2.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 KSA03345.1 - 0.16 11.6 0.5 0.71 9.5 0.0 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA PX PF00787.24 KSA03346.1 - 3.1e-17 62.6 0.0 4.2e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 PX domain Herpes_UL51 PF04540.13 KSA03346.1 - 0.19 11.4 0.0 3.7 7.2 0.0 2.1 2 0 0 2 2 2 0 Herpesvirus UL51 protein NDUFA12 PF05071.16 KSA03347.1 - 9.2e-09 36.0 6.3 8.7e-08 32.9 6.3 2.2 1 1 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 WD40 PF00400.32 KSA03348.1 - 1.8e-05 25.4 1.7 1.7 9.6 0.0 6.5 7 0 0 7 7 7 2 WD domain, G-beta repeat BBS2_Mid PF14783.6 KSA03348.1 - 0.21 11.6 2.3 31 4.7 0.0 4.2 5 0 0 5 5 5 0 Ciliary BBSome complex subunit 2, middle region SART-1 PF03343.13 KSA03349.1 - 1.2e-91 308.2 62.5 1.8e-83 281.2 56.3 2.2 1 1 1 2 2 2 2 SART-1 family MSC PF09402.10 KSA03349.1 - 3.4 7.1 8.9 0.17 11.3 2.7 2.0 2 0 0 2 2 2 0 Man1-Src1p-C-terminal domain E1-E2_ATPase PF00122.20 KSA03350.1 - 3.2e-44 150.6 1.4 3.2e-44 150.6 1.4 2.3 3 0 0 3 3 3 1 E1-E2 ATPase HMA PF00403.26 KSA03350.1 - 2.3e-40 136.9 13.2 6.8e-14 52.1 0.7 3.8 3 0 0 3 3 3 3 Heavy-metal-associated domain Hydrolase PF00702.26 KSA03350.1 - 7.1e-29 101.6 0.0 1.3e-28 100.7 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Poly_export PF02563.16 KSA03350.1 - 0.0056 16.9 0.0 21 5.4 0.0 3.7 3 0 0 3 3 3 1 Polysaccharide biosynthesis/export protein Hydrolase_3 PF08282.12 KSA03350.1 - 0.0063 16.3 0.7 0.0063 16.3 0.7 3.4 3 1 1 4 4 4 1 haloacid dehalogenase-like hydrolase zinc_ribbon_12 PF11331.8 KSA03350.1 - 0.068 13.0 1.7 18 5.2 0.1 3.3 3 0 0 3 3 3 0 Probable zinc-ribbon domain HAD_2 PF13419.6 KSA03350.1 - 0.069 13.2 0.0 0.23 11.5 0.0 1.9 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Fer2_BFD PF04324.15 KSA03350.1 - 0.64 10.4 4.3 48 4.4 0.1 3.8 3 1 0 3 3 3 0 BFD-like [2Fe-2S] binding domain MAGE_N PF12440.8 KSA03352.1 - 1.3 9.8 5.9 1.5 9.5 5.9 1.1 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal Xpo1 PF08389.12 KSA03353.1 - 5.7e-32 110.8 9.8 5.7e-32 110.8 9.8 4.3 6 0 0 6 6 6 1 Exportin 1-like protein IBN_N PF03810.19 KSA03353.1 - 6.3e-09 35.6 4.7 1.4e-08 34.5 1.7 3.3 3 0 0 3 3 3 1 Importin-beta N-terminal domain MinE PF03776.14 KSA03353.1 - 0.11 12.5 0.0 0.38 10.8 0.0 1.9 1 0 0 1 1 1 0 Septum formation topological specificity factor MinE DDE_Tnp_ISL3 PF01610.17 KSA03353.1 - 0.24 11.1 1.6 0.6 9.8 0.2 2.3 3 0 0 3 3 3 0 Transposase Guanylate_kin PF00625.21 KSA03354.1 - 3.4e-61 206.1 0.0 3.8e-61 205.9 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.6 KSA03354.1 - 8.1e-08 32.8 0.1 2.1e-07 31.5 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 KSA03354.1 - 2.3e-06 27.8 0.0 2.3e-05 24.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KSA03354.1 - 1.5e-05 25.5 0.1 6.7e-05 23.5 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KSA03354.1 - 0.00023 21.4 0.0 0.0004 20.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 KSA03354.1 - 0.00078 19.5 0.0 0.0012 18.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.6 KSA03354.1 - 0.00096 19.4 0.0 0.0018 18.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KSA03354.1 - 0.001 19.5 0.0 0.0033 17.8 0.0 1.9 2 0 0 2 2 2 1 RNA helicase AAA_24 PF13479.6 KSA03354.1 - 0.0013 18.5 0.4 0.0041 16.9 0.4 1.9 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KSA03354.1 - 0.0014 18.2 0.1 0.009 15.5 0.0 2.2 2 1 1 3 3 3 1 P-loop containing dynein motor region ABC_tran PF00005.27 KSA03354.1 - 0.0019 18.7 0.0 0.002 18.6 0.0 1.4 1 1 0 1 1 1 1 ABC transporter ATPase_2 PF01637.18 KSA03354.1 - 0.0034 17.3 0.1 0.0072 16.3 0.1 1.6 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea DUF2075 PF09848.9 KSA03354.1 - 0.0043 16.3 0.0 0.012 14.8 0.0 1.8 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA PF00004.29 KSA03354.1 - 0.005 17.3 0.7 0.024 15.0 0.1 2.1 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 KSA03354.1 - 0.0054 16.6 0.0 0.0082 16.1 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_14 PF13173.6 KSA03354.1 - 0.0056 16.7 0.0 0.0099 15.9 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KSA03354.1 - 0.0073 16.1 0.1 0.012 15.3 0.0 1.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KSA03354.1 - 0.0077 16.2 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain T2SSE PF00437.20 KSA03354.1 - 0.011 14.8 0.0 0.017 14.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Rad17 PF03215.15 KSA03354.1 - 0.011 15.6 0.1 0.028 14.3 0.0 1.7 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_29 PF13555.6 KSA03354.1 - 0.013 15.2 1.0 0.022 14.5 0.2 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain NTPase_1 PF03266.15 KSA03354.1 - 0.02 14.8 0.0 0.025 14.5 0.0 1.3 1 0 0 1 1 1 0 NTPase MobB PF03205.14 KSA03354.1 - 0.023 14.6 0.3 0.18 11.7 0.0 2.4 2 2 1 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B KAP_NTPase PF07693.14 KSA03354.1 - 0.035 13.3 0.1 0.094 11.9 0.1 1.6 1 1 0 1 1 1 0 KAP family P-loop domain Viral_helicase1 PF01443.18 KSA03354.1 - 0.07 12.9 0.0 0.094 12.4 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Cytidylate_kin PF02224.18 KSA03354.1 - 0.078 12.7 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase Adeno_IVa2 PF02456.15 KSA03354.1 - 0.091 11.5 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 Adenovirus IVa2 protein AAA_17 PF13207.6 KSA03354.1 - 0.097 13.1 0.1 1.6 9.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 KSA03354.1 - 0.098 12.2 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 KSA03354.1 - 0.11 13.0 2.4 0.21 12.1 2.4 1.7 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KSA03354.1 - 0.12 12.3 0.3 0.24 11.4 0.0 1.8 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) HIG_1_N PF04588.13 KSA03355.1 - 2.4e-17 62.9 0.4 3.3e-17 62.4 0.4 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region eIF-1a PF01176.19 KSA03355.1 - 0.056 13.3 0.0 0.17 11.7 0.0 1.7 2 0 0 2 2 2 0 Translation initiation factor 1A / IF-1 ATP19 PF11022.8 KSA03355.1 - 0.07 13.5 0.6 3.4 8.1 0.1 2.6 2 1 0 2 2 2 0 ATP synthase subunit K DUF4199 PF13858.6 KSA03355.1 - 2 8.8 4.6 0.56 10.6 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) Aminotran_5 PF00266.19 KSA03356.1 - 2.2e-14 53.2 0.1 9.8e-11 41.2 0.0 3.1 2 1 1 3 3 3 2 Aminotransferase class-V Aminotran_1_2 PF00155.21 KSA03356.1 - 0.00014 21.2 0.0 0.0014 17.9 0.0 2.1 2 0 0 2 2 2 1 Aminotransferase class I and II Met_gamma_lyase PF06838.11 KSA03356.1 - 0.073 11.6 0.1 0.13 10.8 0.1 1.4 1 0 0 1 1 1 0 Methionine gamma-lyase ChAPs PF09295.10 KSA03357.1 - 1.1e-142 475.7 0.2 1.6e-142 475.2 0.2 1.2 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_19 PF14559.6 KSA03357.1 - 4.9e-09 36.6 0.1 0.00073 20.0 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KSA03357.1 - 9.2e-06 25.8 2.1 0.0044 17.2 0.1 3.7 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 KSA03357.1 - 0.00016 21.6 2.8 1.9 8.9 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KSA03357.1 - 0.0076 16.3 1.3 20 5.6 0.1 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KSA03357.1 - 0.011 16.5 0.0 1.6 9.8 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 KSA03357.1 - 0.053 13.6 0.0 21 5.4 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 KSA03357.1 - 0.14 12.1 0.1 0.14 12.1 0.1 3.4 4 0 0 4 4 4 0 Putative TPR-like repeat TFIID-31kDa PF02291.15 KSA03358.1 - 4.8e-50 168.7 0.1 6.2e-50 168.4 0.1 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit TPK_catalytic PF04263.16 KSA03359.1 - 5.1e-34 116.9 0.0 6.9e-34 116.5 0.0 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain DUF1713 PF08213.11 KSA03360.1 - 1.2e-12 47.5 22.2 1.8e-12 46.9 22.2 1.3 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) Ham1p_like PF01725.16 KSA03361.1 - 2.3e-55 187.5 0.0 2.5e-55 187.3 0.0 1.0 1 0 0 1 1 1 1 Ham1 family DUF5640 PF18692.1 KSA03361.1 - 0.095 12.7 0.4 8.8 6.4 0.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5640) DUF3602 PF12223.8 KSA03362.1 - 1.6e-27 95.9 21.6 3.3e-12 46.8 0.4 4.1 1 1 3 4 4 4 4 Protein of unknown function (DUF3602) DUF3484 PF11983.8 KSA03362.1 - 0.028 15.5 8.7 0.31 12.2 0.1 2.6 2 1 0 2 2 2 0 Membrane-attachment and polymerisation-promoting switch AFOR_N PF02730.15 KSA03362.1 - 0.61 9.9 5.4 4.9 7.0 0.0 3.3 3 1 0 4 4 4 0 Aldehyde ferredoxin oxidoreductase, N-terminal domain Fcf1 PF04900.12 KSA03365.1 - 1.1e-36 125.1 0.3 1.9e-36 124.4 0.3 1.4 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 KSA03365.1 - 2e-13 50.7 0.0 3.4e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 PIN like domain Imm-NTF2 PF15655.6 KSA03365.1 - 0.013 15.8 0.0 0.024 14.9 0.0 1.4 1 0 0 1 1 1 0 NTF2 fold immunity protein Metallophos PF00149.28 KSA03366.1 - 3.4e-12 47.3 1.4 6.3e-12 46.4 1.4 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase UBA PF00627.31 KSA03367.1 - 4.9e-08 32.7 0.0 9.6e-08 31.8 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain UBA_4 PF14555.6 KSA03367.1 - 0.083 12.7 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain tRNA-synt_1d PF00750.19 KSA03368.1 - 7.5e-115 383.6 6.3 9.3e-115 383.3 6.3 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 KSA03368.1 - 1.7e-29 102.4 0.3 6.7e-29 100.5 0.3 2.1 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 KSA03368.1 - 5e-06 27.0 0.0 1.4e-05 25.6 0.0 1.8 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain IPT PF01745.16 KSA03368.1 - 0.084 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Isopentenyl transferase DUF4393 PF14337.6 KSA03368.1 - 0.13 12.1 1.0 0.59 9.9 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4393) PINIT PF14324.6 KSA03369.1 - 3e-33 115.2 0.0 3e-33 115.2 0.0 3.2 4 1 1 5 5 5 1 PINIT domain zf-MIZ PF02891.20 KSA03369.1 - 2.7e-22 78.3 4.0 4.7e-22 77.5 4.0 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger SAP PF02037.27 KSA03369.1 - 6.8e-10 38.5 0.1 1.2e-09 37.7 0.1 1.4 1 0 0 1 1 1 1 SAP domain zf-Nse PF11789.8 KSA03369.1 - 4.6e-08 32.8 2.5 5.5e-08 32.5 0.7 2.1 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_2 PF13923.6 KSA03369.1 - 0.34 10.8 2.8 0.7 9.8 2.8 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KSA03369.1 - 0.43 10.8 4.4 0.88 9.8 4.4 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING SHS2_Rpb7-N PF03876.17 KSA03370.1 - 1.4e-18 67.0 0.0 2.4e-18 66.3 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 KSA03370.1 - 3.9e-16 59.1 0.1 5.9e-16 58.6 0.1 1.3 1 0 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.12 KSA03370.1 - 0.057 13.6 0.0 0.082 13.1 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 Ribosomal_L13 PF00572.18 KSA03371.1 - 2.4e-45 153.8 0.1 3.7e-45 153.2 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L13 RNA_pol_Rpb2_6 PF00562.28 KSA03372.1 - 2.5e-125 418.6 0.1 5.8e-125 417.4 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KSA03372.1 - 6.3e-69 231.6 0.0 9.4e-69 231.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 KSA03372.1 - 2.4e-48 164.3 0.0 4.9e-48 163.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 KSA03372.1 - 1.8e-34 118.0 0.2 4.1e-34 116.9 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.13 KSA03372.1 - 1.5e-25 89.3 0.4 3.5e-25 88.1 0.4 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 KSA03372.1 - 2.4e-24 85.3 0.1 5e-24 84.3 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 KSA03372.1 - 7.7e-23 80.8 1.3 2.4e-22 79.3 1.3 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 MRNIP PF15749.5 KSA03372.1 - 0.014 16.2 0.2 0.033 14.9 0.2 1.7 1 0 0 1 1 1 0 MRN-interacting protein RNA_pol_Rpb2_45 PF10385.9 KSA03372.1 - 0.099 12.9 1.1 1.2 9.5 0.3 2.6 2 0 0 2 2 2 0 RNA polymerase beta subunit external 1 domain Ribosomal_L23 PF00276.20 KSA03373.1 - 7.2e-10 39.1 0.0 2e-09 37.7 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein L23 TB2_DP1_HVA22 PF03134.19 KSA03374.1 - 9.9e-11 41.4 1.5 9.9e-11 41.4 1.5 2.5 3 0 0 3 3 3 1 TB2/DP1, HVA22 family adh_short PF00106.25 KSA03375.1 - 3.3e-18 65.8 0.0 3.8e-13 49.3 0.0 3.1 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KSA03375.1 - 1.1e-07 31.7 0.0 2.1e-06 27.5 0.0 2.4 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KSA03375.1 - 0.0028 17.6 0.0 0.0059 16.5 0.0 1.4 1 0 0 1 1 1 1 KR domain ISN1 PF06437.11 KSA03376.1 - 1.9e-178 593.6 0.0 2.1e-178 593.4 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase Ribosomal_S4e PF00900.20 KSA03377.1 - 9.5e-38 128.0 1.0 1.5e-36 124.2 0.3 2.2 2 0 0 2 2 2 1 Ribosomal family S4e 40S_S4_C PF16121.5 KSA03377.1 - 1.2e-22 79.3 0.1 2.6e-22 78.2 0.1 1.6 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 KSA03377.1 - 1.4e-08 34.7 0.2 1.4e-07 31.5 0.1 2.3 2 0 0 2 2 2 1 RS4NT (NUC023) domain S4 PF01479.25 KSA03377.1 - 3.3e-08 33.1 0.0 6.3e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 KSA03377.1 - 9.2e-06 25.4 2.5 9.2e-06 25.4 2.5 3.2 3 0 0 3 3 3 1 KOW motif CIA30 PF08547.12 KSA03378.1 - 2.9e-45 154.2 0.0 3.6e-45 153.8 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) SGBP_B_XBD PF18329.1 KSA03378.1 - 0.0044 17.0 0.8 0.058 13.3 0.0 2.1 1 1 1 2 2 2 1 Surface glycan-binding protein B xyloglucan binding domain CBM_11 PF03425.13 KSA03378.1 - 0.019 14.8 0.1 0.031 14.1 0.1 1.3 1 0 0 1 1 1 0 Carbohydrate binding domain (family 11) Choline_transpo PF04515.12 KSA03379.1 - 3.6e-82 276.2 24.5 3.6e-82 276.2 24.5 2.2 2 0 0 2 2 2 1 Plasma-membrane choline transporter Metallophos_2 PF12850.7 KSA03380.1 - 5.9e-08 33.1 0.0 1.1e-07 32.1 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Raftlin PF15250.6 KSA03380.1 - 2.1 7.0 10.8 2.6 6.7 10.8 1.1 1 0 0 1 1 1 0 Raftlin FAM60A PF15396.6 KSA03380.1 - 2.2 8.2 8.8 3 7.8 8.8 1.2 1 0 0 1 1 1 0 Protein Family FAM60A MCM_bind PF09739.9 KSA03380.1 - 2.4 6.5 11.9 3.3 6.1 11.9 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor SLC12 PF03522.15 KSA03380.1 - 6.8 5.6 12.4 9 5.2 12.4 1.1 1 0 0 1 1 1 0 Solute carrier family 12 NOT2_3_5 PF04153.18 KSA03381.1 - 6.5e-34 116.8 0.6 7.8e-34 116.6 0.6 1.1 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family AAA_18 PF13238.6 KSA03382.1 - 4.4e-28 98.4 1.0 1.6e-27 96.6 0.1 1.9 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 KSA03382.1 - 1.2e-06 29.0 0.0 4.4e-06 27.2 0.0 1.9 1 1 1 2 2 2 1 AAA domain AAA PF00004.29 KSA03382.1 - 0.00038 20.9 0.0 0.0012 19.3 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KSA03382.1 - 0.00084 19.5 0.1 0.16 12.1 0.0 2.5 2 2 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KSA03382.1 - 0.0031 17.8 0.0 0.0045 17.3 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KSA03382.1 - 0.005 17.2 0.0 0.01 16.2 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain KTI12 PF08433.10 KSA03382.1 - 0.0054 16.2 0.0 0.0099 15.4 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Thymidylate_kin PF02223.17 KSA03382.1 - 0.0056 16.4 0.0 0.37 10.5 0.1 2.4 2 0 0 2 2 2 1 Thymidylate kinase ADK PF00406.22 KSA03382.1 - 0.0063 16.6 0.0 0.52 10.4 0.0 2.2 2 0 0 2 2 2 1 Adenylate kinase RNA_helicase PF00910.22 KSA03382.1 - 0.0072 16.7 0.0 0.015 15.7 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_28 PF13521.6 KSA03382.1 - 0.0094 16.2 0.2 0.028 14.7 0.0 2.0 2 1 0 2 2 2 1 AAA domain Hpr_kinase_C PF07475.12 KSA03382.1 - 0.0095 15.5 0.1 0.72 9.4 0.0 2.2 2 0 0 2 2 2 1 HPr Serine kinase C-terminal domain Glutaredoxin PF00462.24 KSA03382.1 - 0.021 15.0 0.0 0.063 13.5 0.0 1.8 1 0 0 1 1 1 0 Glutaredoxin Viral_helicase1 PF01443.18 KSA03382.1 - 0.024 14.4 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NACHT PF05729.12 KSA03382.1 - 0.033 14.1 0.0 0.06 13.3 0.0 1.4 1 0 0 1 1 1 0 NACHT domain IF2_N PF04760.15 KSA03382.1 - 0.035 13.9 0.1 0.56 10.1 0.0 2.6 3 0 0 3 3 3 0 Translation initiation factor IF-2, N-terminal region AAA_19 PF13245.6 KSA03382.1 - 0.035 14.4 0.0 0.54 10.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain dNK PF01712.19 KSA03382.1 - 0.052 13.4 1.2 1.1 9.1 0.4 2.2 1 1 0 2 2 2 0 Deoxynucleoside kinase CPT PF07931.12 KSA03382.1 - 0.07 13.0 0.0 0.19 11.5 0.0 1.7 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_5 PF07728.14 KSA03382.1 - 0.074 13.0 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 KSA03382.1 - 0.08 12.8 0.0 0.17 11.7 0.0 1.7 2 0 0 2 2 2 0 NTPase TrwB_AAD_bind PF10412.9 KSA03382.1 - 0.081 11.8 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Heme_oxygenase PF01126.20 KSA03383.1 - 7.1e-25 88.0 2.8 1.2e-24 87.3 2.8 1.3 1 1 0 1 1 1 1 Heme oxygenase Ribosomal_S6 PF01250.17 KSA03383.1 - 0.0083 16.4 1.3 0.012 15.9 0.3 1.7 2 0 0 2 2 2 1 Ribosomal protein S6 Imm43 PF15570.6 KSA03383.1 - 0.13 12.3 2.3 0.18 11.8 0.3 2.2 2 1 1 3 3 3 0 Immunity protein 43 AA_permease PF00324.21 KSA03384.1 - 7.6e-121 404.0 36.4 9.6e-121 403.7 36.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KSA03384.1 - 1.7e-32 112.8 37.5 2.3e-32 112.4 37.5 1.2 1 0 0 1 1 1 1 Amino acid permease PRELI PF04707.14 KSA03385.1 - 8.7e-42 142.6 0.0 1.1e-41 142.3 0.0 1.0 1 0 0 1 1 1 1 PRELI-like family Chordopox_A33R PF05966.12 KSA03386.1 - 0.057 12.7 0.1 0.11 11.8 0.1 1.5 1 0 0 1 1 1 0 Chordopoxvirus A33R protein Prefoldin_2 PF01920.20 KSA03387.1 - 4.7e-20 71.5 4.9 5.5e-20 71.3 4.9 1.1 1 0 0 1 1 1 1 Prefoldin subunit DUF1192 PF06698.11 KSA03387.1 - 0.046 13.8 0.2 0.091 12.8 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) FliJ PF02050.16 KSA03387.1 - 0.22 11.7 3.7 7.2 6.9 0.2 2.1 2 0 0 2 2 2 0 Flagellar FliJ protein FlaC_arch PF05377.11 KSA03387.1 - 0.41 11.1 6.0 6.4 7.3 0.6 2.8 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Spc29 PF17082.5 KSA03387.1 - 0.74 9.6 5.5 0.41 10.4 1.8 1.9 1 1 1 2 2 2 0 Spindle Pole Component 29 COQ9 PF08511.11 KSA03388.1 - 8.3e-30 102.4 0.1 1.3e-29 101.8 0.1 1.3 1 0 0 1 1 1 1 COQ9 POC1 PF10450.9 KSA03389.1 - 5e-07 29.0 0.4 8.5e-07 28.2 0.4 1.5 1 1 0 1 1 1 1 POC1 chaperone Mpv17_PMP22 PF04117.12 KSA03390.1 - 1.1e-19 70.3 2.8 4.4e-19 68.4 2.8 2.1 1 0 0 1 1 1 1 Mpv17 / PMP22 family NADH_u_ox_C PF12853.7 KSA03391.1 - 4.4e-46 154.8 1.4 6.3e-46 154.3 1.4 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit NADH-u_ox-rdase PF10785.9 KSA03391.1 - 2.3e-29 101.9 0.1 3.7e-29 101.2 0.1 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit HEAT PF02985.22 KSA03392.1 - 2.2e-05 24.3 0.2 1.7 9.1 0.1 4.6 4 0 0 4 4 4 2 HEAT repeat ST7 PF04184.12 KSA03392.1 - 0.076 11.5 4.4 0.13 10.7 4.4 1.3 1 0 0 1 1 1 0 ST7 protein Ipi1_N PF12333.8 KSA03392.1 - 0.58 10.8 3.1 1.6 9.4 0.0 3.5 2 1 0 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation DUF45 PF01863.17 KSA03392.1 - 1.7 8.6 7.9 8.2 6.4 7.9 2.1 1 0 0 1 1 1 0 Protein of unknown function DUF45 ETF PF01012.21 KSA03393.1 - 3e-43 147.8 0.2 3.6e-43 147.6 0.2 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain AAA_18 PF13238.6 KSA03394.1 - 0.015 15.8 0.0 0.048 14.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 KSA03394.1 - 0.017 15.2 0.1 0.047 13.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 KSA03394.1 - 0.031 13.7 0.0 0.43 10.0 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein Torsin PF06309.11 KSA03394.1 - 0.067 13.3 0.1 0.17 12.0 0.0 1.7 2 0 0 2 2 2 0 Torsin KAP_NTPase PF07693.14 KSA03394.1 - 0.077 12.2 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain MeaB PF03308.16 KSA03394.1 - 0.15 11.1 0.0 0.23 10.4 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 KSA03394.1 - 0.18 12.2 0.0 0.41 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AA_permease PF00324.21 KSA03395.1 - 1.9e-144 481.9 37.9 2.1e-144 481.7 37.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KSA03395.1 - 5e-39 134.3 40.6 6.1e-39 134.0 40.6 1.0 1 0 0 1 1 1 1 Amino acid permease DUF4781 PF16013.5 KSA03395.1 - 0.0011 17.8 1.8 0.002 17.0 1.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4781) Mer2 PF09074.10 KSA03396.1 - 9.1e-06 25.6 11.9 9.1e-06 25.6 11.9 2.6 1 1 2 3 3 3 1 Mer2 Sigma70_ner PF04546.13 KSA03396.1 - 0.00021 21.2 3.8 0.00036 20.5 0.7 2.6 2 1 1 3 3 3 1 Sigma-70, non-essential region SpoVR PF04293.13 KSA03396.1 - 0.002 16.9 1.2 0.0035 16.1 1.2 1.5 1 0 0 1 1 1 1 SpoVR like protein PspB PF06667.12 KSA03396.1 - 0.13 12.3 0.3 3.7 7.7 0.2 2.7 2 0 0 2 2 2 0 Phage shock protein B GARP PF16731.5 KSA03396.1 - 0.21 11.3 2.3 1.3 8.6 0.4 2.2 1 1 1 2 2 2 0 Glutamic acid/alanine-rich protein of Trypanosoma LSM PF01423.22 KSA03397.1 - 1.6e-15 56.6 0.1 2.4e-15 55.9 0.1 1.3 1 0 0 1 1 1 1 LSM domain Gemin6 PF06372.12 KSA03397.1 - 0.078 12.5 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Gemin6 protein Aldolase_II PF00596.21 KSA03398.1 - 3.6e-44 150.9 0.0 4.4e-44 150.6 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Nop PF01798.18 KSA03399.1 - 1.6e-83 279.7 0.2 1.6e-83 279.7 0.2 1.9 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 KSA03399.1 - 1.4e-20 73.4 1.5 1.4e-20 73.4 1.5 2.4 2 1 0 2 2 2 1 NOP5NT (NUC127) domain DUF4604 PF15377.6 KSA03399.1 - 0.24 11.8 40.5 0.47 10.8 40.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) NARP1 PF12569.8 KSA03399.1 - 4.3 6.1 30.8 2.1 7.2 28.4 1.8 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 SLC12 PF03522.15 KSA03399.1 - 5 6.0 24.6 9.9 5.1 24.6 1.4 1 0 0 1 1 1 0 Solute carrier family 12 RR_TM4-6 PF06459.12 KSA03399.1 - 6 6.6 32.1 2.5 7.9 29.4 1.7 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 RNA_polI_A34 PF08208.11 KSA03399.1 - 6.8 6.7 62.7 13 5.8 62.7 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Dna2 PF08696.11 KSA03400.1 - 4.7e-58 196.3 0.2 1.9e-57 194.3 0.0 2.3 2 0 0 2 2 2 1 DNA replication factor Dna2 AAA_12 PF13087.6 KSA03400.1 - 2.6e-50 170.8 0.3 2.6e-50 170.8 0.3 2.7 3 0 0 3 3 3 1 AAA domain AAA_11 PF13086.6 KSA03400.1 - 1.3e-29 103.8 9.0 3.5e-15 56.5 0.0 3.9 3 1 1 4 4 4 2 AAA domain AAA_30 PF13604.6 KSA03400.1 - 4.8e-13 49.3 0.0 1.5e-12 47.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KSA03400.1 - 1.5e-11 44.8 0.0 4e-11 43.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain Cas_Cas4 PF01930.17 KSA03400.1 - 2e-07 31.2 0.5 1.6e-06 28.3 0.1 2.6 3 0 0 3 3 3 1 Domain of unknown function DUF83 Viral_helicase1 PF01443.18 KSA03400.1 - 2.5e-07 30.7 0.1 0.036 13.8 0.0 3.9 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase SRP54 PF00448.22 KSA03400.1 - 0.0013 18.4 0.0 0.0033 17.1 0.0 1.7 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain Helicase_RecD PF05127.14 KSA03400.1 - 0.0035 17.2 0.0 0.0084 16.0 0.0 1.7 1 0 0 1 1 1 1 Helicase AAA_18 PF13238.6 KSA03400.1 - 0.012 16.2 0.2 0.14 12.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain UvrD-helicase PF00580.21 KSA03400.1 - 0.02 14.4 0.2 0.02 14.4 0.2 4.2 4 1 0 5 5 5 0 UvrD/REP helicase N-terminal domain AAA_5 PF07728.14 KSA03400.1 - 0.029 14.4 0.0 0.1 12.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ResIII PF04851.15 KSA03400.1 - 0.038 14.0 0.2 0.038 14.0 0.2 3.1 3 1 0 3 3 2 0 Type III restriction enzyme, res subunit cobW PF02492.19 KSA03400.1 - 0.04 13.5 0.0 0.1 12.2 0.0 1.7 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 KSA03400.1 - 0.046 14.1 0.0 0.13 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 KSA03400.1 - 0.074 12.6 0.1 0.21 11.1 0.1 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 KSA03400.1 - 0.095 12.7 0.3 1.1 9.3 0.1 2.8 2 0 0 2 2 2 0 AAA domain CbiA PF01656.23 KSA03400.1 - 0.096 12.8 0.0 0.44 10.6 0.0 2.1 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain NTPase_1 PF03266.15 KSA03400.1 - 0.11 12.4 0.4 0.32 10.9 0.4 1.7 1 0 0 1 1 1 0 NTPase AAA_29 PF13555.6 KSA03400.1 - 0.14 11.9 0.2 0.35 10.7 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.6 KSA03400.1 - 0.17 12.0 0.0 0.52 10.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain Sel1 PF08238.12 KSA03401.1 - 2e-26 91.8 24.9 0.00031 21.3 0.0 10.8 11 0 0 11 11 11 7 Sel1 repeat TPR_14 PF13428.6 KSA03401.1 - 0.004 17.8 2.4 7.1 7.7 0.0 5.7 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.6 KSA03401.1 - 0.0058 16.6 3.0 3.4 7.9 0.0 5.0 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 KSA03401.1 - 0.023 14.6 0.4 28 4.8 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF4834 PF16118.5 KSA03401.1 - 0.058 14.4 0.2 0.058 14.4 0.2 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4834) TPR_8 PF13181.6 KSA03401.1 - 0.18 12.1 20.8 3.1 8.2 0.1 9.9 10 1 0 10 10 10 0 Tetratricopeptide repeat MIT PF04212.18 KSA03401.1 - 0.43 10.7 7.0 16 5.7 0.1 5.5 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain TPR_19 PF14559.6 KSA03401.1 - 2.3 8.8 7.4 10 6.7 0.0 5.1 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.28 KSA03401.1 - 2.4 8.1 24.0 0.9 9.5 0.1 7.7 9 0 0 9 9 9 0 Tetratricopeptide repeat V_ATPase_I PF01496.19 KSA03402.1 - 8.1e-285 946.9 17.1 8.3e-221 735.2 17.5 2.0 1 1 1 2 2 2 2 V-type ATPase 116kDa subunit family MFS_1 PF07690.16 KSA03403.1 - 1.9e-37 129.0 62.3 2.2e-25 89.3 36.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily HLH PF00010.26 KSA03404.1 - 1.4e-17 63.3 0.1 5.2e-17 61.5 0.1 2.0 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain bZIP_1 PF00170.21 KSA03404.1 - 0.017 15.2 0.5 0.056 13.5 0.5 1.9 1 0 0 1 1 1 0 bZIP transcription factor zf-rbx1 PF12678.7 KSA03405.1 - 8.8e-10 38.7 4.0 1.6e-09 37.9 4.0 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KSA03405.1 - 3.7e-09 36.8 6.7 5.4e-09 36.2 1.8 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KSA03405.1 - 3.3e-07 30.0 6.8 2.2e-06 27.4 2.2 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KSA03405.1 - 2.1e-06 27.6 3.3 4.3e-06 26.6 3.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 KSA03405.1 - 2.2e-06 27.3 5.4 0.00026 20.7 0.2 2.8 2 0 0 2 2 2 2 RING-like zinc finger zf-C3HC4 PF00097.25 KSA03405.1 - 5.8e-06 26.1 4.7 1.1e-05 25.2 4.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KSA03405.1 - 1.5e-05 24.7 2.1 3.3e-05 23.6 2.1 1.6 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 KSA03405.1 - 8e-05 22.2 0.7 0.00022 20.8 0.7 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 KSA03405.1 - 9.8e-05 22.3 3.3 0.00023 21.1 2.7 2.0 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KSA03405.1 - 0.00062 19.6 1.2 0.00062 19.6 1.2 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KSA03405.1 - 0.0025 17.8 2.2 0.0051 16.8 2.2 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 KSA03405.1 - 0.065 13.4 4.6 0.26 11.5 4.6 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain MRP-L47 PF06984.13 KSA03405.1 - 0.087 13.0 0.9 20 5.4 0.2 2.5 2 0 0 2 2 2 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) zf-C3H2C3 PF17122.5 KSA03405.1 - 0.35 10.9 4.2 0.63 10.1 2.6 2.2 2 0 0 2 2 2 0 Zinc-finger Ferlin_C PF16165.5 KSA03405.1 - 0.36 10.8 3.9 0.15 12.0 0.4 2.2 2 0 0 2 2 2 0 Ferlin C-terminus zf-RING_4 PF14570.6 KSA03405.1 - 3.8 7.4 7.0 0.44 10.4 1.4 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain RINGv PF12906.7 KSA03405.1 - 7.7 6.7 7.6 0.31 11.2 1.3 1.9 2 0 0 2 2 2 0 RING-variant domain DUF3246 PF11596.8 KSA03406.1 - 1.7e-27 96.5 85.5 1.7e-27 96.5 85.5 8.3 1 1 3 5 5 5 1 Protein of unknown function (DUF3246) Endotoxin_C2 PF18449.1 KSA03407.1 - 0.12 12.8 0.8 37 4.7 0.0 4.7 7 0 0 7 7 7 0 Delta endotoxin Hamartin PF04388.12 KSA03407.1 - 1.5 7.4 5.0 0.22 10.2 0.1 2.0 2 0 0 2 2 2 0 Hamartin protein Complex1_LYR_2 PF13233.6 KSA03408.1 - 7.1e-18 65.1 0.0 1e-17 64.6 0.0 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 KSA03408.1 - 2.8e-10 40.1 0.0 1e-09 38.3 0.0 1.8 2 0 0 2 2 2 1 Complex 1 protein (LYR family) PLA2_B PF01735.18 KSA03408.1 - 0.1 11.0 0.0 0.12 10.8 0.0 1.1 1 0 0 1 1 1 0 Lysophospholipase catalytic domain Glyco_transf_15 PF01793.16 KSA03409.1 - 3e-112 375.1 18.0 4e-112 374.7 18.0 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase GLTP PF08718.11 KSA03410.1 - 7.3e-49 165.9 0.1 1.1e-48 165.3 0.1 1.3 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Hormone_2 PF00123.20 KSA03410.1 - 0.14 12.0 0.2 0.34 10.8 0.2 1.6 1 0 0 1 1 1 0 Peptide hormone Glyco_hydro_3_C PF01915.22 KSA03412.1 - 8.7e-65 218.5 0.0 1.5e-64 217.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KSA03412.1 - 1.2e-44 153.0 0.0 2e-44 152.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KSA03412.1 - 7.2e-26 90.1 0.1 6.4e-25 87.1 0.0 2.6 3 0 0 3 3 3 1 Fibronectin type III-like domain PA14 PF07691.12 KSA03412.1 - 6.2e-18 65.0 0.0 1.1e-17 64.2 0.0 1.4 1 0 0 1 1 1 1 PA14 domain GFO_IDH_MocA PF01408.22 KSA03413.1 - 6.4e-16 59.3 0.0 9.3e-16 58.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Sugar_tr PF00083.24 KSA03414.1 - 2.5e-85 287.0 22.1 2.9e-85 286.8 22.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KSA03414.1 - 1.2e-25 90.2 17.1 5.5e-23 81.5 13.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KSA03414.1 - 3.7e-08 32.4 27.3 2.4e-05 23.1 3.1 3.3 2 2 1 3 3 3 2 MFS/sugar transport protein TRI12 PF06609.13 KSA03414.1 - 0.0004 18.9 0.7 0.0004 18.9 0.7 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 KSA03414.1 - 0.014 13.8 1.7 0.34 9.3 0.1 2.3 2 0 0 2 2 2 0 Transmembrane secretion effector GFD1 PF17331.2 KSA03414.1 - 0.47 10.7 4.3 0.35 11.1 2.6 1.6 2 0 0 2 2 2 0 GFD1 mRNA transport factor Baculo_11_kDa PF06143.11 KSA03414.1 - 6.9 6.3 6.2 9.3 5.9 0.4 3.0 3 0 0 3 3 3 0 Baculovirus 11 kDa family Sugar_tr PF00083.24 KSA03415.1 - 4.6e-82 276.3 25.5 5.4e-82 276.1 25.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KSA03415.1 - 5.1e-25 88.2 22.0 3.6e-19 68.9 7.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Cellulase PF00150.18 KSA03416.1 - 9.1e-33 113.9 0.3 1.7e-32 113.0 0.2 1.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Sugar_tr PF00083.24 KSA03417.1 - 3.5e-86 289.9 25.3 4.1e-86 289.6 25.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KSA03417.1 - 1.5e-25 89.9 16.0 1.2e-22 80.4 13.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KSA03417.1 - 1.4e-07 30.4 25.6 4.9e-05 22.1 1.3 3.3 2 2 2 4 4 4 2 MFS/sugar transport protein TRI12 PF06609.13 KSA03417.1 - 0.00017 20.1 2.5 0.00017 20.1 2.5 2.2 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF4293 PF14126.6 KSA03417.1 - 3.2 8.0 11.6 0.23 11.7 4.5 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4293) DUF2841 PF11001.8 KSA03418.1 - 1.4e-31 109.1 1.2 3.8e-31 107.7 1.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) MTS PF05175.14 KSA03419.1 - 3.6e-06 26.6 0.0 6.9e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 KSA03419.1 - 3.8e-06 26.8 0.0 5.5e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmC_N PF17827.1 KSA03419.1 - 0.0053 17.3 0.1 0.011 16.3 0.1 1.6 1 0 0 1 1 1 1 PrmC N-terminal domain Methyltransf_25 PF13649.6 KSA03419.1 - 0.027 15.2 0.0 0.051 14.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_20 PF12147.8 KSA03419.1 - 0.045 12.9 0.0 0.073 12.2 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Gcd10p PF04189.13 KSA03420.1 - 1.6e-101 339.4 2.7 2e-101 339.1 2.7 1.1 1 0 0 1 1 1 1 Gcd10p family AvrM_N PF18247.1 KSA03420.1 - 0.0047 16.8 0.2 0.025 14.5 0.2 2.3 1 0 0 1 1 1 1 Flax-rust effector AvrM N-terminal domain Methyltr_RsmB-F PF01189.17 KSA03421.1 - 2.9e-81 271.9 0.0 7.9e-81 270.5 0.0 1.8 2 0 0 2 2 2 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 KSA03421.1 - 5.1e-08 33.3 0.1 2.9e-07 30.9 0.0 2.3 2 0 0 2 2 2 1 N-terminal domain of 16S rRNA methyltransferase RsmF FtsJ PF01728.19 KSA03421.1 - 0.021 14.9 0.0 0.042 14.0 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase FlgM PF04316.13 KSA03421.1 - 7.3 7.0 7.4 2.4 8.6 1.7 3.3 3 1 0 3 3 3 0 Anti-sigma-28 factor, FlgM FGF-BP1 PF06473.12 KSA03421.1 - 9.7 6.0 15.7 3.1 7.6 0.2 2.2 2 0 0 2 2 2 0 FGF binding protein 1 (FGF-BP1) Actin PF00022.19 KSA03422.1 - 4e-46 157.4 0.0 1.4e-27 96.3 0.0 2.4 2 1 0 2 2 2 2 Actin GvpO PF05800.11 KSA03422.1 - 0.04 13.9 4.4 0.08 12.9 1.8 2.5 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpO SopE_GEF PF07487.13 KSA03422.1 - 2.7 8.1 6.3 5.3 7.1 0.2 3.0 2 1 1 3 3 3 0 SopE GEF domain CAP_N PF01213.19 KSA03423.1 - 3.7e-117 391.4 3.0 3.7e-117 391.4 3.0 1.4 1 1 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 KSA03423.1 - 1.1e-53 181.0 2.5 1.8e-53 180.3 2.5 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal PRIMA1 PF16101.5 KSA03423.1 - 4.7 7.3 12.9 1.9 8.5 5.2 2.4 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 DnaJ_C PF01556.18 KSA03424.1 - 2.9e-42 144.2 0.4 4.9e-42 143.5 0.4 1.4 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KSA03424.1 - 1.2e-25 89.4 1.5 2.2e-25 88.5 1.5 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KSA03424.1 - 3.8e-14 52.8 22.1 6.5e-14 52.0 22.1 1.4 1 0 0 1 1 1 1 DnaJ central domain IL3 PF02059.15 KSA03424.1 - 0.061 13.4 0.1 0.13 12.4 0.1 1.4 1 0 0 1 1 1 0 Interleukin-3 DUF4416 PF14385.6 KSA03424.1 - 0.18 11.7 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4416) Anti-TRAP PF15777.5 KSA03424.1 - 0.61 10.1 17.6 0.18 11.8 4.7 2.5 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein MFS_1 PF07690.16 KSA03425.1 - 1.6e-36 126.0 38.0 3.2e-34 118.4 21.3 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KSA03425.1 - 6.3e-09 35.2 11.5 6.3e-09 35.2 11.5 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter Alg14 PF08660.11 KSA03425.1 - 0.099 12.6 1.1 1.1 9.2 0.0 2.5 2 0 0 2 2 2 0 Oligosaccharide biosynthesis protein Alg14 like DUF2722 PF10846.8 KSA03426.1 - 6.6e-06 25.3 38.6 7.3e-05 21.9 38.6 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2722) PRK PF00485.18 KSA03427.1 - 1e-05 25.3 0.2 4.2e-05 23.4 0.2 1.9 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 KSA03427.1 - 2.1e-05 25.1 0.0 6.4e-05 23.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KSA03427.1 - 0.00013 22.4 0.0 0.00023 21.6 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_15 PF13175.6 KSA03427.1 - 0.00086 19.1 0.7 0.0017 18.1 0.7 1.5 1 1 0 1 1 1 1 AAA ATPase domain G-alpha PF00503.20 KSA03427.1 - 0.0032 16.7 0.1 0.0059 15.8 0.1 1.6 1 1 0 1 1 1 1 G-protein alpha subunit AAA_28 PF13521.6 KSA03427.1 - 0.0042 17.3 0.0 0.0072 16.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KSA03427.1 - 0.0064 16.7 0.0 0.024 14.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain CPT PF07931.12 KSA03427.1 - 0.0097 15.8 0.1 0.016 15.0 0.1 1.6 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_27 PF13514.6 KSA03427.1 - 0.016 14.8 0.0 0.027 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 KSA03427.1 - 0.019 14.9 0.0 0.034 14.1 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain KTI12 PF08433.10 KSA03427.1 - 0.02 14.3 0.0 0.037 13.5 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Zeta_toxin PF06414.12 KSA03427.1 - 0.03 13.6 0.0 0.053 12.8 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin DUF5439 PF17507.2 KSA03427.1 - 0.032 14.4 1.9 2.5 8.4 0.1 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5439) AAA_29 PF13555.6 KSA03427.1 - 0.036 13.8 0.0 0.081 12.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Cytidylate_kin PF02224.18 KSA03427.1 - 0.048 13.4 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 Cytidylate kinase ABC_tran PF00005.27 KSA03427.1 - 0.07 13.7 0.0 0.13 12.8 0.0 1.6 1 1 0 1 1 1 0 ABC transporter T2SSE PF00437.20 KSA03427.1 - 0.07 12.2 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF4516 PF14990.6 KSA03427.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4516) APS_kinase PF01583.20 KSA03427.1 - 0.14 12.0 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase GNAT_acetyltr_2 PF13718.6 KSA03428.1 - 2.5e-100 334.5 0.0 8.6e-100 332.8 0.0 2.0 1 0 0 1 1 1 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 KSA03428.1 - 6.3e-92 307.5 7.6 1.3e-91 306.5 7.6 1.6 1 0 0 1 1 1 1 Possible tRNA binding domain Helicase_RecD PF05127.14 KSA03428.1 - 2.7e-65 219.5 0.0 1.8e-64 216.8 0.0 2.3 2 1 0 2 2 2 1 Helicase DUF1726 PF08351.11 KSA03428.1 - 1.1e-34 118.2 0.6 1.4e-33 114.7 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1726) AAA_22 PF13401.6 KSA03428.1 - 0.0019 18.5 0.0 0.87 9.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain YARHG PF13308.6 KSA03428.1 - 0.0057 16.5 0.0 0.15 12.0 0.0 3.2 3 0 0 3 3 3 1 YARHG domain AAA_30 PF13604.6 KSA03428.1 - 0.0058 16.4 0.0 0.12 12.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain Kin17_mid PF10357.9 KSA03428.1 - 0.014 15.3 0.2 0.051 13.5 0.2 2.0 1 0 0 1 1 1 0 Domain of Kin17 curved DNA-binding protein DEAD PF00270.29 KSA03428.1 - 0.047 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 DEAD/DEAH box helicase Acetyltransf_1 PF00583.25 KSA03428.1 - 0.075 13.3 0.0 0.26 11.5 0.0 1.9 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KSA03428.1 - 0.11 13.0 0.0 0.64 10.5 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Chalcone_3 PF16036.5 KSA03428.1 - 1.9 8.6 4.7 1.7 8.7 0.8 2.8 3 0 0 3 3 3 0 Chalcone isomerase-like NDT80_PhoG PF05224.12 KSA03429.1 - 4.4e-48 164.0 0.5 1.9e-47 161.9 0.0 2.1 2 0 0 2 2 2 1 NDT80 / PhoG like DNA-binding family LSM PF01423.22 KSA03430.1 - 3.5e-18 65.1 0.4 4.9e-18 64.6 0.4 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KSA03430.1 - 0.0027 17.8 0.1 0.0035 17.4 0.1 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain Gemin7 PF11095.8 KSA03430.1 - 0.038 13.9 0.1 1.2 9.1 0.0 2.1 2 0 0 2 2 2 0 Gem-associated protein 7 (Gemin7) Hfq PF17209.3 KSA03430.1 - 0.05 13.3 0.1 0.12 12.0 0.0 1.6 2 0 0 2 2 2 0 Hfq protein DUF1461 PF07314.11 KSA03430.1 - 0.058 13.3 0.1 0.058 13.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1461) zf-C2H2_10 PF16588.5 KSA03431.1 - 9.2e-12 44.5 5.6 9.2e-12 44.5 5.6 1.8 2 0 0 2 2 2 1 C2H2 zinc-finger YyzF PF14116.6 KSA03431.1 - 0.48 10.5 2.3 0.68 10.0 0.2 2.1 2 0 0 2 2 2 0 YyzF-like protein A2L_zn_ribbon PF08792.10 KSA03431.1 - 1.4 8.7 7.6 9.2 6.1 1.0 2.5 2 0 0 2 2 2 0 A2L zinc ribbon domain Rft-1 PF04506.13 KSA03432.1 - 1.4e-156 522.3 31.4 1.7e-156 522.0 31.4 1.0 1 0 0 1 1 1 1 Rft protein CBFD_NFYB_HMF PF00808.23 KSA03433.1 - 1.1e-26 92.9 0.1 2.2e-26 91.9 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KSA03433.1 - 3.6e-05 24.1 6.6 8.3e-05 23.0 0.1 2.5 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KSA03433.1 - 0.026 14.6 0.1 0.062 13.4 0.1 1.7 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold Bromo_TP PF07524.13 KSA03433.1 - 0.075 13.0 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Bromodomain associated zf-RING_2 PF13639.6 KSA03434.1 - 7.5e-12 45.4 5.5 1.7e-11 44.2 5.5 1.7 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KSA03434.1 - 7.5e-09 35.7 2.8 1.7e-08 34.6 2.8 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KSA03434.1 - 1.3e-08 34.6 5.1 3.9e-08 33.0 5.1 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KSA03434.1 - 3.3e-07 30.0 4.3 8.8e-07 28.7 4.3 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KSA03434.1 - 1.2e-05 25.1 2.0 1.2e-05 25.1 2.0 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KSA03434.1 - 4.3e-05 23.1 3.3 4.3e-05 23.1 3.3 2.8 3 0 0 3 3 3 1 RING-like zinc finger zf-RING_5 PF14634.6 KSA03434.1 - 8.7e-05 22.4 3.2 8.7e-05 22.4 3.2 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KSA03434.1 - 0.00024 21.1 1.1 0.00049 20.1 1.1 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KSA03434.1 - 0.00026 20.8 3.7 0.0005 19.9 3.7 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KSA03434.1 - 0.00053 19.9 2.3 0.0011 18.9 0.5 2.5 1 1 1 2 2 2 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 KSA03434.1 - 0.011 15.3 2.8 0.025 14.2 2.8 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type RINGv PF12906.7 KSA03434.1 - 0.034 14.3 2.4 0.078 13.1 2.4 1.6 1 1 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 KSA03434.1 - 0.32 11.2 6.2 0.99 9.6 6.2 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.11 KSA03434.1 - 1.2 9.5 3.9 2.7 8.4 3.9 1.6 1 0 0 1 1 1 0 RING-like domain Methyltr_RsmB-F PF01189.17 KSA03435.1 - 2e-40 138.6 0.0 4.9e-39 134.1 0.0 2.3 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 KSA03435.1 - 0.00082 19.5 0.0 0.0016 18.6 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase UAF_Rrn10 PF05234.11 KSA03436.1 - 3.4e-10 40.2 0.1 6.6e-10 39.3 0.1 1.5 1 1 0 1 1 1 1 UAF complex subunit Rrn10 Lon_C PF05362.13 KSA03438.1 - 1e-63 214.6 0.0 2e-63 213.6 0.0 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 KSA03438.1 - 1.4e-30 106.8 0.0 1.4e-30 106.8 0.0 2.3 3 0 0 3 3 2 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 KSA03438.1 - 6.2e-22 78.4 0.1 3e-21 76.2 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KSA03438.1 - 1.2e-07 31.8 0.0 2.9e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_PrkA PF08298.11 KSA03438.1 - 1.4e-05 24.2 0.0 3.2e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 PrkA AAA domain RuvB_N PF05496.12 KSA03438.1 - 1.6e-05 24.7 0.0 0.00038 20.2 0.0 2.6 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KSA03438.1 - 5.1e-05 23.7 0.0 0.0002 21.8 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KSA03438.1 - 0.00012 22.4 0.1 0.015 15.6 0.1 2.6 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KSA03438.1 - 0.00013 21.7 0.0 0.00037 20.3 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.13 KSA03438.1 - 0.00033 20.0 0.1 0.00086 18.6 0.1 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain NTPase_1 PF03266.15 KSA03438.1 - 0.00084 19.3 0.1 0.074 13.0 0.0 2.7 1 1 1 2 2 2 1 NTPase Zeta_toxin PF06414.12 KSA03438.1 - 0.0027 17.0 0.4 0.011 15.0 0.1 2.1 2 0 0 2 2 2 1 Zeta toxin AAA_18 PF13238.6 KSA03438.1 - 0.0028 18.2 0.0 0.0028 18.2 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_19 PF13245.6 KSA03438.1 - 0.0029 17.9 1.7 0.076 13.4 0.1 2.7 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.6 KSA03438.1 - 0.0038 17.3 0.1 0.013 15.5 0.0 2.1 2 0 0 2 2 1 1 AAA domain ChlI PF13541.6 KSA03438.1 - 0.0047 16.8 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase Mg_chelatase PF01078.21 KSA03438.1 - 0.019 14.3 0.0 0.33 10.3 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI TsaE PF02367.17 KSA03438.1 - 0.032 14.2 0.5 0.094 12.7 0.0 2.0 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 KSA03438.1 - 0.039 14.3 0.0 0.11 12.8 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Cytidylate_kin PF02224.18 KSA03438.1 - 0.044 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Cytidylate kinase AAA_3 PF07726.11 KSA03438.1 - 0.047 13.6 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KSA03438.1 - 0.053 13.0 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_30 PF13604.6 KSA03438.1 - 0.06 13.1 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KSA03438.1 - 0.084 13.0 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KSA03438.1 - 0.14 12.1 0.0 0.44 10.5 0.0 1.9 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.6 KSA03438.1 - 0.16 12.2 0.2 0.59 10.4 0.0 2.1 2 0 0 2 2 1 0 AAA domain ABC_tran PF00005.27 KSA03438.1 - 0.17 12.4 0.0 0.17 12.4 0.0 2.7 3 1 0 3 3 2 0 ABC transporter Zip PF02535.22 KSA03438.1 - 0.5 9.5 7.6 2.6 7.2 0.8 2.3 2 0 0 2 2 2 0 ZIP Zinc transporter Cytidylate_kin2 PF13189.6 KSA03438.1 - 2.9 8.0 5.6 32 4.6 0.0 3.3 3 0 0 3 3 3 0 Cytidylate kinase-like family zf-UBR PF02207.20 KSA03439.1 - 1.3e-14 54.1 11.4 1.3e-14 54.1 11.4 3.0 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) MCM2_N PF12619.8 KSA03440.1 - 1.8e-46 158.2 31.5 4.8e-46 156.8 30.8 2.0 2 0 0 2 2 2 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.6 KSA03440.1 - 1.9e-12 47.7 1.0 5.3e-12 46.2 0.1 2.1 2 0 0 2 2 2 1 MCM N-terminal domain MCM_OB PF17207.3 KSA03440.1 - 2.2e-12 46.9 0.1 3.6e-12 46.2 0.1 1.2 1 0 0 1 1 1 1 MCM OB domain DUF3113 PF11310.8 KSA03440.1 - 0.031 14.2 0.0 0.47 10.4 0.0 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3113) MCM PF00493.23 KSA03441.1 - 1.5e-94 315.3 0.0 2.1e-94 314.8 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_lid PF17855.1 KSA03441.1 - 2.1e-25 88.9 0.2 5.3e-25 87.6 0.2 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 KSA03441.1 - 2.9e-09 36.6 0.1 6.4e-07 29.0 0.0 2.7 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KSA03441.1 - 2.5e-07 30.8 0.0 7e-07 29.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 KSA03441.1 - 0.00029 20.6 0.1 0.0023 17.7 0.1 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.11 KSA03441.1 - 0.0012 18.7 0.0 0.0041 17.0 0.0 1.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Drc1-Sld2 PF11719.8 KSA03441.1 - 0.049 13.2 6.0 0.077 12.5 6.0 1.2 1 0 0 1 1 1 0 DNA replication and checkpoint protein RST PF12174.8 KSA03441.1 - 0.084 12.8 0.0 0.28 11.1 0.0 1.8 1 0 0 1 1 1 0 RCD1-SRO-TAF4 (RST) plant domain AAA_30 PF13604.6 KSA03441.1 - 0.091 12.5 0.1 0.18 11.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KSA03441.1 - 0.38 11.2 1.9 0.95 9.9 0.4 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PBP1_TM PF14812.6 KSA03441.1 - 1.7 9.0 9.1 4.2 7.8 9.1 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Metallophos PF00149.28 KSA03442.1 - 0.0033 17.9 0.0 0.0053 17.3 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase KRE1 PF17056.5 KSA03443.1 - 3.8e-21 74.6 14.8 3.8e-21 74.6 14.8 1.5 2 0 0 2 2 2 1 Killer toxin-resistance protein 1 Methyltransf_16 PF10294.9 KSA03444.1 - 2.3e-14 53.5 0.0 2.9e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 KSA03444.1 - 0.00039 20.3 0.0 0.00058 19.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KSA03444.1 - 0.0013 19.3 0.9 0.013 16.2 0.1 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KSA03444.1 - 0.0024 18.6 0.2 0.031 15.0 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_2 PF00891.18 KSA03444.1 - 0.049 12.9 0.0 0.085 12.1 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_12 PF08242.12 KSA03444.1 - 0.12 13.2 0.1 0.25 12.1 0.1 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 KSA03444.1 - 0.2 11.4 0.9 0.28 11.0 0.1 1.7 2 0 0 2 2 2 0 Methyltransferase domain Glyco_hydro_125 PF06824.11 KSA03446.1 - 1.3e-173 577.7 0.0 1.6e-173 577.4 0.0 1.1 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) ATP_bind_1 PF03029.17 KSA03447.1 - 2.6e-80 269.7 0.1 4.2e-80 269.0 0.1 1.3 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 KSA03447.1 - 3e-07 30.2 1.7 6.3e-06 25.9 0.5 3.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_24 PF13479.6 KSA03447.1 - 2.2e-05 24.3 0.1 0.00019 21.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KSA03447.1 - 0.00011 22.2 0.0 0.0027 17.8 0.0 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_33 PF13671.6 KSA03447.1 - 0.00011 22.4 0.0 0.00034 20.8 0.0 1.9 2 0 0 2 2 1 1 AAA domain MeaB PF03308.16 KSA03447.1 - 0.00028 20.0 0.1 0.39 9.7 0.0 2.4 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 KSA03447.1 - 0.00056 19.8 0.0 3 7.7 0.0 3.4 3 1 0 3 3 3 2 RsgA GTPase AAA_22 PF13401.6 KSA03447.1 - 0.00077 19.7 0.0 0.0029 17.9 0.0 2.1 3 0 0 3 3 2 1 AAA domain NACHT PF05729.12 KSA03447.1 - 0.001 19.0 0.0 0.0018 18.2 0.0 1.4 1 0 0 1 1 1 1 NACHT domain PduV-EutP PF10662.9 KSA03447.1 - 0.0015 18.3 0.1 0.1 12.3 0.0 2.7 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 KSA03447.1 - 0.0036 16.8 0.0 0.12 11.9 0.0 2.6 3 0 0 3 3 3 1 Ferrous iron transport protein B SRP54 PF00448.22 KSA03447.1 - 0.0041 16.8 0.0 0.056 13.1 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Roc PF08477.13 KSA03447.1 - 0.0064 16.7 0.1 0.97 9.7 0.0 2.8 2 1 1 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase CLP1_P PF16575.5 KSA03447.1 - 0.0068 16.2 0.0 2.5 7.8 0.0 2.5 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Arf PF00025.21 KSA03447.1 - 0.0078 15.7 0.0 1.1 8.6 0.0 3.1 2 1 0 2 2 2 1 ADP-ribosylation factor family AAA_16 PF13191.6 KSA03447.1 - 0.0083 16.5 0.1 0.027 14.9 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 KSA03447.1 - 0.014 15.9 1.4 0.031 14.8 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KSA03447.1 - 0.015 15.0 0.0 0.029 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 KSA03447.1 - 0.016 14.8 0.1 0.093 12.3 0.1 2.2 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 KSA03447.1 - 0.017 14.6 0.0 0.037 13.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region NB-ARC PF00931.22 KSA03447.1 - 0.024 13.8 0.0 0.069 12.3 0.0 1.7 1 0 0 1 1 1 0 NB-ARC domain SRPRB PF09439.10 KSA03447.1 - 0.025 14.0 2.2 0.66 9.4 0.0 2.6 3 0 0 3 3 2 0 Signal recognition particle receptor beta subunit PRK PF00485.18 KSA03447.1 - 0.026 14.3 0.0 0.065 13.0 0.0 1.7 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Phage_Gp19 PF09355.10 KSA03447.1 - 0.03 14.7 0.0 0.089 13.2 0.0 1.7 1 0 0 1 1 1 0 Phage protein Gp19/Gp15/Gp42 DUF87 PF01935.17 KSA03447.1 - 0.049 13.7 0.7 2.1 8.4 0.0 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain DUF1943 PF09172.11 KSA03447.1 - 0.06 12.6 3.9 0.038 13.2 1.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1943) TsaE PF02367.17 KSA03447.1 - 0.073 13.1 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE FtsK_SpoIIIE PF01580.18 KSA03447.1 - 0.13 11.6 1.2 2.2 7.6 0.1 2.6 3 0 0 3 3 3 0 FtsK/SpoIIIE family SF3a60_bindingd PF12108.8 KSA03447.1 - 6.3 6.8 6.0 16 5.5 0.0 2.8 3 0 0 3 3 2 0 Splicing factor SF3a60 binding domain EMC3_TMCO1 PF01956.16 KSA03448.1 - 1.3e-42 145.4 0.3 2.4e-42 144.6 0.0 1.5 2 0 0 2 2 2 1 Integral membrane protein EMC3/TMCO1-like SUIM_assoc PF16619.5 KSA03448.1 - 0.085 12.9 0.0 0.22 11.6 0.0 1.6 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 DUF3767 PF12597.8 KSA03449.1 - 1.5e-38 130.7 0.2 2.2e-38 130.2 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) CPP1-like PF11833.8 KSA03449.1 - 0.15 11.7 1.4 0.19 11.4 0.2 1.8 1 1 1 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Rpn3_C PF08375.11 KSA03449.1 - 0.62 10.5 5.3 1.2 9.7 5.3 1.4 1 0 0 1 1 1 0 Proteasome regulatory subunit C-terminal AAA PF00004.29 KSA03450.1 - 2.1e-56 190.0 0.0 6.9e-43 146.2 0.0 3.0 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 KSA03450.1 - 3.2e-24 85.1 0.4 8.5e-24 83.8 0.4 1.8 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.6 KSA03450.1 - 5.9e-11 43.0 0.7 0.0019 18.6 0.0 4.3 2 2 2 4 4 4 2 AAA ATPase domain AAA_lid_3 PF17862.1 KSA03450.1 - 4.3e-10 39.2 0.0 2.6e-07 30.4 0.0 2.6 2 0 0 2 2 2 1 AAA+ lid domain Bac_DnaA PF00308.18 KSA03450.1 - 6.1e-07 29.5 0.1 4e-05 23.6 0.1 2.7 2 1 0 2 2 2 1 Bacterial dnaA protein NACHT PF05729.12 KSA03450.1 - 2.3e-06 27.6 2.5 0.0063 16.5 0.2 3.8 3 1 0 3 3 3 2 NACHT domain ATPase PF06745.13 KSA03450.1 - 5.6e-06 25.9 0.0 0.0039 16.6 0.0 2.4 2 0 0 2 2 2 2 KaiC ABC_tran PF00005.27 KSA03450.1 - 1.2e-05 25.9 5.1 0.0098 16.4 0.1 4.2 4 0 0 4 4 4 2 ABC transporter AAA_14 PF13173.6 KSA03450.1 - 1.2e-05 25.3 0.0 0.093 12.8 0.1 3.0 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 KSA03450.1 - 2.4e-05 24.1 0.2 0.099 12.4 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein RNA_helicase PF00910.22 KSA03450.1 - 2.5e-05 24.6 0.0 0.34 11.3 0.0 3.6 2 0 0 2 2 2 2 RNA helicase AAA_22 PF13401.6 KSA03450.1 - 4.4e-05 23.8 3.5 1.7 8.9 0.0 4.4 2 2 2 4 4 4 2 AAA domain AAA_5 PF07728.14 KSA03450.1 - 4.6e-05 23.4 0.0 0.52 10.3 0.0 3.3 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 KSA03450.1 - 6e-05 22.7 0.2 0.68 9.5 0.1 3.9 3 1 0 4 4 4 1 AAA domain RuvB_N PF05496.12 KSA03450.1 - 0.00013 21.8 0.0 0.019 14.7 0.0 2.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KSA03450.1 - 0.00022 21.4 0.0 0.013 15.6 0.0 2.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 KSA03450.1 - 0.00026 21.5 0.3 0.35 11.4 0.0 3.5 3 0 0 3 3 3 1 AAA domain DUF2075 PF09848.9 KSA03450.1 - 0.00058 19.2 2.0 0.43 9.8 0.0 3.7 4 0 0 4 4 4 1 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.6 KSA03450.1 - 0.00074 19.3 0.1 0.51 10.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 KSA03450.1 - 0.0031 17.2 0.2 1.4 8.6 0.0 3.1 3 1 0 3 3 3 1 Sigma-54 interaction domain AAA_7 PF12775.7 KSA03450.1 - 0.0061 16.1 0.0 0.76 9.3 0.0 2.7 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_33 PF13671.6 KSA03450.1 - 0.0094 16.1 0.0 0.17 12.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 KSA03450.1 - 0.011 15.0 0.2 7.1 5.7 0.1 3.3 2 0 0 2 2 2 0 NB-ARC domain ATPase_2 PF01637.18 KSA03450.1 - 0.011 15.7 0.1 0.011 15.7 0.1 4.3 5 1 1 6 6 4 0 ATPase domain predominantly from Archaea TsaE PF02367.17 KSA03450.1 - 0.014 15.4 0.0 1.1 9.3 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 KSA03450.1 - 0.015 14.7 0.1 0.58 9.5 0.1 2.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_29 PF13555.6 KSA03450.1 - 0.016 14.9 0.3 0.016 14.9 0.3 3.4 4 0 0 4 4 3 0 P-loop containing region of AAA domain TIP49 PF06068.13 KSA03450.1 - 0.02 14.1 0.1 0.3 10.2 0.0 2.3 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_30 PF13604.6 KSA03450.1 - 0.036 13.8 0.0 0.32 10.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 KSA03450.1 - 0.04 14.3 0.1 1.9 8.9 0.1 2.9 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 KSA03450.1 - 0.044 13.5 0.0 1.1 8.9 0.0 2.8 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase PhoH PF02562.16 KSA03450.1 - 0.13 11.7 0.8 14 5.0 0.0 2.9 3 0 0 3 3 2 0 PhoH-like protein MICSWaP PF17018.5 KSA03450.1 - 0.14 11.7 8.5 0.017 14.7 3.2 2.2 2 0 0 2 2 2 0 Spore wall protein Vps4_C PF09336.10 KSA03450.1 - 0.23 11.5 1.4 3.6 7.7 0.3 3.2 2 1 1 3 3 3 0 Vps4 C terminal oligomerisation domain ResIII PF04851.15 KSA03450.1 - 1 9.3 5.2 2.3 8.2 0.1 3.5 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit Sld5 PF05916.11 KSA03451.1 - 6.1e-19 68.5 0.4 9.8e-19 67.8 0.4 1.3 1 0 0 1 1 1 1 GINS complex protein Med11 PF10280.9 KSA03452.1 - 1.4e-22 80.6 1.4 1.4e-22 80.6 1.4 1.5 2 0 0 2 2 2 1 Mediator complex protein DUF4854 PF16146.5 KSA03452.1 - 0.0064 16.8 0.4 0.013 15.8 0.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4854) Syntaxin-6_N PF09177.11 KSA03452.1 - 0.015 15.8 2.7 0.056 14.0 2.7 2.0 1 1 0 1 1 1 0 Syntaxin 6, N-terminal ING PF12998.7 KSA03452.1 - 0.029 15.0 0.6 0.029 15.0 0.6 2.2 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding ZapB PF06005.12 KSA03452.1 - 0.05 14.1 6.7 0.15 12.5 0.1 2.6 2 2 0 2 2 2 0 Cell division protein ZapB Mur_ligase_M PF08245.12 KSA03453.1 - 0.00085 19.4 0.1 0.0088 16.1 0.1 2.8 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 KSA03453.1 - 0.037 14.3 0.0 0.13 12.6 0.0 1.9 2 0 0 2 2 2 0 Mur ligase family, glutamate ligase domain WD40 PF00400.32 KSA03454.1 - 3.2e-07 30.9 3.5 0.14 13.0 0.0 5.4 5 0 0 5 5 5 2 WD domain, G-beta repeat WD40 PF00400.32 KSA03455.1 - 2.3e-46 154.8 22.5 6.2e-08 33.2 0.3 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KSA03455.1 - 5.2e-11 42.7 1.0 0.017 15.4 0.0 5.0 1 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KSA03455.1 - 1.5e-06 27.5 3.8 0.21 10.5 0.0 4.3 1 1 4 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KSA03455.1 - 5.1e-06 25.4 9.5 0.0074 15.0 0.0 4.9 3 2 2 5 5 5 3 Nucleoporin Nup120/160 eIF2A PF08662.11 KSA03455.1 - 0.00093 19.1 0.2 0.016 15.1 0.1 2.3 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 KSA03455.1 - 0.0038 17.1 0.0 2.2 8.3 0.0 3.5 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 KSA03455.1 - 0.039 12.5 0.0 0.44 9.0 0.0 2.1 2 0 0 2 2 2 0 Cytochrome D1 heme domain IKI3 PF04762.12 KSA03455.1 - 0.12 10.4 0.2 0.58 8.1 0.0 1.9 1 1 1 2 2 2 0 IKI3 family UPF0052 PF01933.18 KSA03456.1 - 2.8e-57 194.2 0.0 4e-57 193.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 Saf_2TM PF18303.1 KSA03456.1 - 0.0012 18.4 0.0 0.003 17.2 0.0 1.6 1 0 0 1 1 1 1 SAVED-fused 2TM effector domain IF-2B PF01008.17 KSA03457.1 - 3.9e-70 236.3 0.0 4.4e-70 236.1 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family Sin_N PF04801.13 KSA03458.1 - 1.1e-19 70.9 0.3 2.1e-19 70.0 0.3 1.4 1 1 0 1 1 1 1 Sin-like protein conserved region DEAD PF00270.29 KSA03459.1 - 3.3e-42 144.2 0.5 4.7e-42 143.7 0.5 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KSA03459.1 - 5e-09 36.4 2.2 1.4e-08 35.0 0.0 2.4 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit DUF4217 PF13959.6 KSA03460.1 - 3.6e-20 72.0 0.1 8.5e-20 70.8 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.31 KSA03460.1 - 2.5e-18 66.4 0.0 4.7e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DcpS_C PF11969.8 KSA03461.1 - 3.7e-34 117.6 0.1 6.4e-34 116.9 0.1 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.12 KSA03461.1 - 1.4e-32 112.6 0.2 2.2e-32 112.0 0.2 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal HIT PF01230.23 KSA03461.1 - 0.0069 17.1 0.2 0.029 15.1 0.2 2.0 2 0 0 2 2 2 1 HIT domain MMM1 PF10296.9 KSA03462.1 - 1.4e-08 34.2 0.2 0.00035 19.8 0.0 2.3 2 0 0 2 2 2 2 Maintenance of mitochondrial morphology protein 1 GFO_IDH_MocA PF01408.22 KSA03463.1 - 4.4e-23 82.4 0.1 7e-23 81.7 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KSA03463.1 - 1.6e-12 47.5 0.0 3.2e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Semialdhyde_dh PF01118.24 KSA03463.1 - 0.008 16.6 0.0 0.013 16.0 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 KSA03463.1 - 0.033 14.3 0.0 0.05 13.7 0.0 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus CoA_binding PF02629.19 KSA03463.1 - 0.18 12.5 0.0 0.36 11.5 0.0 1.5 1 0 0 1 1 1 0 CoA binding domain Sacchrp_dh_NADP PF03435.18 KSA03463.1 - 0.21 11.9 0.0 0.45 10.8 0.0 1.6 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain L51_S25_CI-B8 PF05047.16 KSA03464.1 - 8e-10 38.5 0.0 1.1e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain LigB PF02900.18 KSA03465.1 - 6.9e-30 104.0 0.0 9.7e-30 103.6 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase DUF2674 PF10879.8 KSA03465.1 - 0.024 14.2 0.1 0.33 10.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2674) CAF-1_p150 PF11600.8 KSA03466.1 - 0.63 9.7 24.7 1.5 8.5 24.7 1.5 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal FRB_dom PF08771.11 KSA03467.1 - 0.028 14.8 0.4 0.07 13.6 0.3 1.8 1 1 0 1 1 1 0 FKBP12-rapamycin binding domain BTB PF00651.31 KSA03468.1 - 1.1e-19 70.7 0.1 1.3e-08 35.1 0.1 2.8 2 1 0 2 2 2 2 BTB/POZ domain Ank_2 PF12796.7 KSA03468.1 - 3e-05 24.5 0.0 9.6e-05 22.9 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KSA03468.1 - 7.9e-05 23.1 0.0 0.00026 21.5 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KSA03468.1 - 0.0062 16.8 0.0 0.018 15.3 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 KSA03468.1 - 0.011 16.2 0.0 0.04 14.4 0.0 2.1 1 0 0 1 1 1 0 Ankyrin repeat Ank_3 PF13606.6 KSA03468.1 - 0.031 14.8 0.0 1 10.1 0.0 3.1 2 0 0 2 2 2 0 Ankyrin repeat Adenine_glyco PF03352.13 KSA03468.1 - 0.14 11.9 3.0 3.5 7.4 0.8 2.3 2 0 0 2 2 2 0 Methyladenine glycosylase NUC173 PF08161.12 KSA03469.1 - 1.3e-74 250.3 3.4 5e-70 235.3 0.1 3.5 4 0 0 4 4 4 2 NUC173 domain Ribosomal_S16 PF00886.19 KSA03470.1 - 2.3e-23 82.0 0.0 3.5e-23 81.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S16 TnsD PF15978.5 KSA03470.1 - 0.088 11.8 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 Tn7-like transposition protein D PDR_assoc PF08370.11 KSA03470.1 - 0.13 12.0 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Plant PDR ABC transporter associated FKBP_C PF00254.28 KSA03471.1 - 0.074 13.4 0.1 0.12 12.7 0.1 1.4 1 0 0 1 1 1 0 FKBP-type peptidyl-prolyl cis-trans isomerase Ribosomal_L10 PF00466.20 KSA03473.1 - 8.3e-26 90.0 0.2 1.8e-25 89.0 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L10 RL10P_insert PF17777.1 KSA03473.1 - 9.5e-23 80.0 0.0 1.5e-22 79.3 0.0 1.3 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 KSA03473.1 - 1.3e-19 70.6 2.7 1.3e-19 70.6 2.7 2.0 2 0 0 2 2 2 1 60s Acidic ribosomal protein Metallophos PF00149.28 KSA03474.1 - 6.5e-08 33.3 1.0 1.4e-07 32.2 1.0 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Sigma_reg_N PF13800.6 KSA03474.1 - 0.12 12.7 0.0 0.33 11.3 0.0 1.7 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Homeodomain PF00046.29 KSA03475.1 - 3.3e-15 55.7 4.4 8.9e-15 54.3 4.4 1.8 1 0 0 1 1 1 1 Homeodomain Glyco_hydro_30C PF17189.4 KSA03475.1 - 0.029 14.6 2.4 0.073 13.3 0.6 2.7 2 0 0 2 2 2 0 Glycosyl hydrolase family 30 beta sandwich domain Ribosomal_S13 PF00416.22 KSA03476.1 - 8.4e-56 187.9 2.5 9.6e-56 187.7 2.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 KSA03476.1 - 0.0023 16.8 0.0 0.0026 16.6 0.0 1.2 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) DUF3196 PF11428.8 KSA03476.1 - 0.023 14.2 0.0 0.033 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3196) FTA4 PF13093.6 KSA03476.1 - 0.042 13.7 0.0 0.052 13.4 0.0 1.1 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Ribosomal_L4 PF00573.22 KSA03477.1 - 1e-42 146.0 0.0 1.2e-42 145.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Peptidase_S10 PF00450.22 KSA03478.1 - 7.9e-108 361.5 0.4 1.2e-107 360.9 0.4 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase Serinc PF03348.15 KSA03478.1 - 0.019 13.9 0.3 0.027 13.4 0.3 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) E1-E2_ATPase PF00122.20 KSA03478.1 - 0.022 14.3 0.3 0.043 13.3 0.3 1.4 1 0 0 1 1 1 0 E1-E2 ATPase Phosphorylase PF00343.20 KSA03479.1 - 0 1020.0 0.2 0 1019.7 0.2 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase BLF1 PF17752.1 KSA03479.1 - 0.0056 16.0 0.0 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 Burkholderia lethal factor 1 DUF3437 PF11919.8 KSA03479.1 - 0.08 12.9 0.2 0.29 11.1 0.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3437) DUF4709 PF15821.5 KSA03479.1 - 0.11 12.7 0.1 9.2 6.6 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4709) Spike_NTD PF16451.5 KSA03480.1 - 0.1 12.0 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Spike glycoprotein N-terminal domain WD40 PF00400.32 KSA03482.1 - 2.1e-11 44.1 8.9 0.01 16.6 0.3 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KSA03482.1 - 0.013 15.8 0.0 0.97 9.8 0.0 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain PWWP PF00855.17 KSA03483.1 - 5.2e-21 74.9 0.0 5.2e-21 74.9 0.0 2.5 2 0 0 2 2 2 1 PWWP domain DUF2052 PF09747.9 KSA03483.1 - 0.15 12.2 23.0 0.062 13.4 10.3 2.7 3 0 0 3 3 3 0 Coiled-coil domain containing protein (DUF2052) GAGA_bind PF06217.12 KSA03483.1 - 0.3 11.3 13.3 0.061 13.6 5.4 2.3 2 0 0 2 2 2 0 GAGA binding protein-like family Neur_chan_memb PF02932.16 KSA03483.1 - 3 7.9 8.0 1.8 8.6 0.7 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region PGA2 PF07543.12 KSA03483.1 - 3 7.8 24.2 0.29 11.1 12.7 2.5 2 0 0 2 2 2 0 Protein trafficking PGA2 eIF3_subunit PF08597.10 KSA03483.1 - 4.3 7.2 37.1 0.58 10.0 20.1 2.5 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit SRF-TF PF00319.18 KSA03484.1 - 4.2e-21 74.2 0.1 5.9e-21 73.7 0.1 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Synaphin PF05835.12 KSA03484.1 - 0.38 11.0 3.4 0.98 9.7 0.2 2.2 2 0 0 2 2 2 0 Synaphin protein MFMR_assoc PF16596.5 KSA03484.1 - 0.88 10.0 9.5 4.6 7.7 2.4 2.3 2 0 0 2 2 2 0 Disordered region downstream of MFMR TSGP1 PF07771.11 KSA03484.1 - 1.9 8.6 6.0 0.33 11.1 1.5 1.9 2 0 0 2 2 2 0 Tick salivary peptide group 1 MRI PF15325.6 KSA03484.1 - 6.7 7.8 8.4 24 6.1 2.4 2.4 2 1 0 2 2 2 0 Modulator of retrovirus infection DUF4810 PF16068.5 KSA03484.1 - 8 7.1 8.8 0.37 11.4 3.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4810) PSP1 PF04468.12 KSA03485.1 - 7.5e-36 122.3 0.1 1.4e-35 121.4 0.1 1.5 1 0 0 1 1 1 1 PSP1 C-terminal conserved region bZIP_2 PF07716.15 KSA03486.1 - 1.3e-11 44.4 9.8 1.3e-11 44.4 9.8 2.6 2 1 0 3 3 3 1 Basic region leucine zipper bZIP_1 PF00170.21 KSA03486.1 - 0.072 13.2 17.0 0.3 11.2 17.0 2.0 1 1 0 1 1 1 0 bZIP transcription factor YabA PF06156.13 KSA03486.1 - 5.1 7.8 12.4 1.1 10.0 8.0 2.0 1 1 1 2 2 2 0 Initiation control protein YabA Pkinase PF00069.25 KSA03487.1 - 2.8e-62 210.5 0.0 1.1e-37 129.9 0.1 2.6 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KSA03487.1 - 1.3e-28 100.0 0.2 3.6e-21 75.6 0.1 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.24 KSA03487.1 - 6.6e-07 29.5 0.0 1.7e-06 28.2 0.0 1.8 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.6 KSA03487.1 - 1.9e-05 24.1 0.1 0.00092 18.6 0.0 2.4 2 0 0 2 2 2 1 Kinase-like PAS_9 PF13426.7 KSA03487.1 - 0.00065 19.9 0.1 0.022 15.0 0.0 2.7 2 0 0 2 2 2 1 PAS domain APH PF01636.23 KSA03487.1 - 0.0016 18.4 0.1 0.008 16.1 0.1 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family PAS PF00989.25 KSA03487.1 - 0.0024 17.8 0.0 0.0071 16.3 0.0 1.7 1 0 0 1 1 1 1 PAS fold Seadorna_VP7 PF07387.11 KSA03487.1 - 0.012 14.7 0.0 0.027 13.5 0.0 1.5 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 KSA03487.1 - 0.02 14.3 0.2 0.074 12.4 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family RNase_T PF00929.24 KSA03488.1 - 6e-32 111.5 0.2 1.4e-31 110.2 0.0 1.6 2 0 0 2 2 2 1 Exonuclease DUF1133 PF06576.11 KSA03488.1 - 0.091 12.1 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1133) eIF-5_eIF-2B PF01873.17 KSA03488.1 - 0.25 11.2 2.9 14 5.6 0.0 3.0 3 0 0 3 3 3 0 Domain found in IF2B/IF5 DUF2781 PF10914.8 KSA03489.1 - 2.6e-39 135.0 12.1 3e-39 134.8 12.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) ACBP PF00887.19 KSA03490.1 - 4.8e-28 97.2 2.7 5.2e-28 97.1 2.7 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein Plus-3 PF03126.18 KSA03492.1 - 1.4e-27 96.4 0.5 4.7e-27 94.7 0.0 2.2 2 0 0 2 2 2 1 Plus-3 domain Ribosomal_L34e PF01199.18 KSA03494.1 - 6.5e-45 151.4 5.3 6.5e-45 151.4 5.3 1.5 2 0 0 2 2 2 1 Ribosomal protein L34e FhuF_C PF11575.8 KSA03494.1 - 0.23 11.4 2.8 8.8 6.4 0.1 2.4 2 0 0 2 2 2 0 FhuF 2Fe-2S C-terminal domain DUF1977 PF09320.11 KSA03494.1 - 0.52 10.6 4.4 0.62 10.4 4.4 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1977) Abhydrolase_1 PF00561.20 KSA03496.1 - 5.8e-07 29.4 0.0 3.7e-06 26.8 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KSA03496.1 - 1.1e-05 24.9 0.0 0.021 14.1 0.0 2.3 2 1 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KSA03496.1 - 0.00045 20.9 0.0 0.0011 19.6 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family tRNA-synt_1c PF00749.21 KSA03498.1 - 6.7e-113 376.7 0.3 9.6e-111 369.6 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (E and Q), catalytic domain tRNA_synt_1c_R1 PF04558.15 KSA03498.1 - 1.7e-52 177.7 4.3 3e-52 176.9 4.3 1.4 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA-synt_1c_C PF03950.18 KSA03498.1 - 1.1e-31 110.1 0.1 3.6e-30 105.1 0.1 2.9 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R2 PF04557.15 KSA03498.1 - 3.8e-10 40.5 7.2 3.8e-10 40.5 7.2 2.9 3 1 0 3 3 3 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 CBM_21 PF03370.13 KSA03499.1 - 1.1e-28 99.7 0.5 1.1e-28 99.7 0.5 1.8 2 0 0 2 2 2 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 KSA03499.1 - 9.5e-09 35.7 0.3 2.6e-08 34.3 0.3 1.7 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) Thg1 PF04446.12 KSA03500.1 - 1e-49 167.7 0.3 1.7e-49 167.0 0.3 1.3 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.6 KSA03500.1 - 3.2e-48 162.9 1.5 4.6e-48 162.4 1.5 1.2 1 0 0 1 1 1 1 Thg1 C terminal domain RNA_pol_Rpb2_6 PF00562.28 KSA03501.1 - 4.2e-113 378.3 0.0 9.5e-113 377.2 0.0 1.6 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KSA03501.1 - 3.2e-40 137.8 0.1 4.6e-40 137.3 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 KSA03501.1 - 1.4e-29 103.1 0.0 2.9e-29 102.0 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.16 KSA03501.1 - 2.6e-28 98.0 0.0 6.3e-28 96.7 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.12 KSA03501.1 - 8.4e-24 83.3 0.0 1.7e-23 82.4 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.20 KSA03501.1 - 1.1e-16 61.0 0.1 2.3e-15 56.8 0.0 2.6 2 1 0 2 2 2 1 RNA polymerase Rpb2, domain 7 DiS_P_DiS PF06750.13 KSA03501.1 - 0.031 14.4 0.4 0.07 13.3 0.4 1.5 1 0 0 1 1 1 0 Bacterial Peptidase A24 N-terminal domain PRK PF00485.18 KSA03502.1 - 1.7e-11 44.2 0.0 2.4e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 KSA03502.1 - 2.5e-05 24.8 0.9 0.00014 22.4 0.1 2.4 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 KSA03502.1 - 2.5e-05 23.6 0.0 4.2e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.6 KSA03502.1 - 4.1e-05 23.8 0.0 0.0023 18.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 KSA03502.1 - 0.00013 21.3 0.0 0.0002 20.6 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain Viral_helicase1 PF01443.18 KSA03502.1 - 0.002 17.9 0.0 0.0029 17.4 0.0 1.2 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_17 PF13207.6 KSA03502.1 - 0.0035 17.8 0.8 0.022 15.2 0.0 2.5 3 0 0 3 3 3 1 AAA domain 6PF2K PF01591.18 KSA03502.1 - 0.0057 16.0 0.0 0.0088 15.4 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase AAA_16 PF13191.6 KSA03502.1 - 0.0063 16.9 0.0 0.0088 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain KTI12 PF08433.10 KSA03502.1 - 0.0068 15.9 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 MeaB PF03308.16 KSA03502.1 - 0.0078 15.2 0.0 0.011 14.7 0.0 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB APS_kinase PF01583.20 KSA03502.1 - 0.016 15.1 0.0 0.036 14.0 0.0 1.6 2 0 0 2 2 1 0 Adenylylsulphate kinase AAA_22 PF13401.6 KSA03502.1 - 0.02 15.2 0.0 0.032 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 KSA03502.1 - 0.028 13.6 0.0 0.043 13.0 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_14 PF13173.6 KSA03502.1 - 0.046 13.7 0.1 0.13 12.3 0.0 1.8 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KSA03502.1 - 0.073 13.5 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 RNA helicase NTPase_1 PF03266.15 KSA03502.1 - 0.074 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 NTPase cobW PF02492.19 KSA03502.1 - 0.089 12.4 0.1 0.21 11.2 0.0 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 KSA03502.1 - 0.089 12.9 0.1 0.22 11.6 0.1 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.27 KSA03502.1 - 0.09 13.3 0.0 0.13 12.8 0.0 1.4 1 0 0 1 1 1 0 ABC transporter ResIII PF04851.15 KSA03502.1 - 0.092 12.7 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit T2SSE PF00437.20 KSA03502.1 - 0.093 11.8 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Ploopntkinase3 PF18751.1 KSA03502.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_5 PF07728.14 KSA03502.1 - 0.11 12.4 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) XLF PF09302.11 KSA03503.1 - 6e-25 88.4 0.4 2.4e-24 86.5 0.0 2.0 2 0 0 2 2 2 1 XLF-Cernunnos, XRcc4-like factor, NHEJ component DNA_pol_alpha_N PF12254.8 KSA03503.1 - 0.093 12.8 2.4 0.22 11.6 2.4 1.6 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal PIN_4 PF13638.6 KSA03504.1 - 2.2e-35 121.8 0.4 5.2e-35 120.6 0.4 1.7 1 0 0 1 1 1 1 PIN domain PIN_9 PF18477.1 KSA03504.1 - 0.039 14.3 0.0 0.12 12.7 0.0 1.9 1 1 1 2 2 2 0 PIN like domain DUF1992 PF09350.10 KSA03504.1 - 0.041 14.1 0.0 0.094 12.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1992) DUF155 PF02582.14 KSA03505.1 - 7e-55 185.8 0.0 1.3e-54 184.9 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 tRNA-synt_1c PF00749.21 KSA03506.1 - 9.2e-115 382.8 0.1 1.2e-114 382.4 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 KSA03506.1 - 4.1e-40 137.5 0.5 8.8e-40 136.4 0.5 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GluRS_N PF18466.1 KSA03506.1 - 3.4e-21 75.4 1.2 3.4e-21 75.4 1.2 2.9 2 0 0 2 2 2 1 Glutamate--tRNA ligase N-terminal domain GST_C PF00043.25 KSA03506.1 - 0.00082 19.5 0.3 0.0023 18.1 0.1 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KSA03506.1 - 0.0041 17.1 0.0 0.011 15.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Gp-FAR-1 PF05823.12 KSA03506.1 - 0.045 14.1 0.1 0.12 12.8 0.1 1.6 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) G_glu_transpept PF01019.21 KSA03507.1 - 3.6e-126 422.0 0.0 4.1e-126 421.8 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase MAGE PF01454.19 KSA03508.1 - 1.3e-39 136.2 0.4 1.9e-39 135.6 0.4 1.2 1 0 0 1 1 1 1 MAGE family FAD_binding_1 PF00667.20 KSA03509.1 - 4.5e-68 229.1 0.0 6.4e-68 228.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KSA03509.1 - 3.6e-33 114.8 0.8 8.3e-33 113.6 0.8 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KSA03509.1 - 1.3e-21 77.2 0.0 1.1e-20 74.3 0.0 2.4 3 0 0 3 3 3 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 KSA03509.1 - 0.034 14.3 0.0 0.1 12.7 0.0 1.8 1 0 0 1 1 1 0 Ferric reductase NAD binding domain VCBS PF13517.6 KSA03509.1 - 0.034 14.7 0.0 0.12 13.0 0.0 2.0 1 0 0 1 1 1 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Beta-Casp PF10996.8 KSA03509.1 - 0.11 12.8 0.0 0.34 11.2 0.0 1.8 1 0 0 1 1 1 0 Beta-Casp domain Ins_P5_2-kin PF06090.12 KSA03510.1 - 5e-29 101.8 2.1 7.1e-29 101.3 2.1 1.2 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase Holin_BhlA PF10960.8 KSA03510.1 - 0.043 13.8 1.5 0.071 13.1 0.2 2.0 2 0 0 2 2 2 0 BhlA holin family AIM24 PF01987.17 KSA03511.1 - 6.2e-19 68.6 0.0 8.9e-19 68.1 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Moricin PF06451.11 KSA03511.1 - 0.14 12.0 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 Moricin MKT1_C PF12246.8 KSA03512.1 - 2.8e-56 190.5 2.1 5.1e-56 189.6 2.1 1.5 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.8 KSA03512.1 - 7.3e-27 93.6 0.7 2.9e-26 91.7 0.7 2.1 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.17 KSA03512.1 - 2.7e-14 53.5 0.1 2.3e-12 47.2 0.0 2.7 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.18 KSA03512.1 - 3.1e-06 27.4 0.0 1.1e-05 25.7 0.0 2.0 1 0 0 1 1 1 1 XPG I-region IBN_N PF03810.19 KSA03513.1 - 4.8e-05 23.2 1.3 0.0085 16.0 0.2 3.6 2 0 0 2 2 2 2 Importin-beta N-terminal domain Xpo1 PF08389.12 KSA03513.1 - 0.0019 18.3 7.4 0.0019 18.3 7.4 5.5 5 2 0 5 5 5 1 Exportin 1-like protein DUF5478 PF17572.2 KSA03513.1 - 0.046 13.8 0.0 0.2 11.8 0.0 2.1 1 0 0 1 1 1 0 Family of unknown function (DUF5478) Brix PF04427.18 KSA03514.1 - 6.7e-27 94.9 0.8 6.7e-27 94.9 0.8 1.4 2 0 0 2 2 2 1 Brix domain tRNA-synt_1c PF00749.21 KSA03514.1 - 0.0078 15.1 1.3 0.013 14.5 1.3 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain Peptidase_C3 PF00548.20 KSA03514.1 - 0.17 11.8 0.1 0.35 10.8 0.1 1.5 1 1 0 1 1 1 0 3C cysteine protease (picornain 3C) P30 PF07390.11 KSA03514.1 - 0.27 11.3 2.5 0.19 11.8 0.2 1.8 1 1 1 2 2 2 0 Mycoplasma P30 protein MaoC_dehydratas PF01575.19 KSA03515.1 - 0.048 13.2 0.0 0.1 12.2 0.0 1.5 2 0 0 2 2 2 0 MaoC like domain Sod_Cu PF00080.20 KSA03516.1 - 1.3e-46 158.3 3.8 1.4e-46 158.1 3.8 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Inhibitor_I9 PF05922.16 KSA03517.1 - 3.2e-09 37.3 0.6 2.5e-08 34.5 0.6 1.9 1 1 0 1 1 1 1 Peptidase inhibitor I9 BRCT PF00533.26 KSA03517.1 - 0.021 15.2 0.1 0.022 15.1 0.1 1.3 1 1 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KSA03517.1 - 0.04 14.3 0.1 0.042 14.3 0.1 1.1 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain DAHP_snth_FXD PF18152.1 KSA03517.1 - 0.06 13.2 0.1 0.1 12.5 0.1 1.6 1 1 0 1 1 1 0 DAHP synthase ferredoxin-like domain Dabb PF07876.12 KSA03517.1 - 0.067 13.8 0.1 0.081 13.6 0.1 1.1 1 0 0 1 1 1 0 Stress responsive A/B Barrel Domain NAD_binding_8 PF13450.6 KSA03517.1 - 0.18 12.1 0.0 0.19 12.0 0.0 1.1 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Glyco_hydro_38N PF01074.22 KSA03518.1 - 2.1e-78 263.6 0.1 3.9e-78 262.7 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 KSA03518.1 - 4.3e-49 167.5 0.6 8.6e-49 166.5 0.6 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 KSA03518.1 - 3.1e-25 88.1 0.0 8.7e-25 86.7 0.0 1.8 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 KSA03518.1 - 2.5e-05 24.3 0.1 0.0003 20.8 0.0 2.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain GUN4 PF05419.12 KSA03518.1 - 4.3 7.4 7.7 25 5.0 0.1 3.3 3 0 0 3 3 3 0 GUN4-like Flocculin_t3 PF13928.6 KSA03519.1 - 1.1e-21 77.1 52.1 2.8e-12 47.0 23.0 3.5 4 0 0 4 4 4 2 Flocculin type 3 repeat GETHR PF05671.11 KSA03519.1 - 0.021 14.2 4.3 2 7.8 0.1 3.7 3 1 1 4 4 4 0 GETHR pentapeptide repeat (5 copies) DUF2401 PF10287.9 KSA03519.1 - 3.9 7.0 7.6 0.96 9.0 1.7 2.2 1 1 1 2 2 2 0 Putative TOS1-like glycosyl hydrolase (DUF2401) DivIC PF04977.15 KSA03520.1 - 0.15 11.8 0.0 0.15 11.8 0.0 3.4 3 0 0 3 3 3 0 Septum formation initiator VPS11_C PF12451.8 KSA03520.1 - 5.9 7.2 5.7 1.1 9.6 0.4 2.6 2 0 0 2 2 2 0 Vacuolar protein sorting protein 11 C terminal Redoxin PF08534.10 KSA03521.1 - 1.2e-35 122.4 0.0 1.4e-35 122.2 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KSA03521.1 - 2e-09 37.4 0.0 2.4e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family PIG-F PF06699.11 KSA03522.1 - 2.3e-50 171.2 5.5 2.7e-50 171.0 5.5 1.0 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F DUF1761 PF08570.10 KSA03522.1 - 0.007 16.6 0.2 0.021 15.1 0.0 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF1761) CPSF_A PF03178.15 KSA03523.1 - 5.7e-102 341.3 0.1 1.9e-99 333.1 0.0 2.4 2 0 0 2 2 2 2 CPSF A subunit region Flocculin_t3 PF13928.6 KSA03524.1 - 1.5e-15 57.4 43.6 7.1e-14 52.0 18.3 5.7 6 3 0 6 6 6 2 Flocculin type 3 repeat Thioredoxin PF00085.20 KSA03525.1 - 1.8e-16 60.0 0.4 4e-11 42.8 0.1 2.4 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 KSA03525.1 - 2.1e-06 28.2 0.4 0.0015 18.9 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 KSA03525.1 - 7.5e-06 25.5 9.4 7.3e-05 22.3 2.1 2.3 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family TraF PF13728.6 KSA03525.1 - 0.00018 21.4 0.0 0.001 18.9 0.0 2.0 2 0 0 2 2 2 1 F plasmid transfer operon protein ER_lumen_recept PF00810.18 KSA03526.1 - 1.3e-35 123.4 0.6 1.3e-35 123.4 0.6 1.4 2 0 0 2 2 2 1 ER lumen protein retaining receptor HlyIII PF03006.20 KSA03526.1 - 0.053 13.2 2.5 0.066 12.9 2.5 1.1 1 0 0 1 1 1 0 Haemolysin-III related Proteasome PF00227.26 KSA03527.1 - 4.8e-38 130.5 0.1 3.7e-37 127.7 0.1 1.9 1 1 0 1 1 1 1 Proteasome subunit zf-Tim10_DDP PF02953.15 KSA03528.1 - 7.5e-23 80.0 2.0 1.4e-22 79.1 2.0 1.4 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF3398 PF11878.8 KSA03528.1 - 0.0068 16.8 1.1 0.01 16.3 1.2 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3398) Ribosomal_S3Ae PF01015.18 KSA03528.1 - 0.015 14.8 0.0 0.02 14.5 0.0 1.1 1 0 0 1 1 1 0 Ribosomal S3Ae family MIF4G PF02854.19 KSA03528.1 - 0.028 14.0 1.7 0.12 11.9 1.7 1.8 1 1 0 1 1 1 0 MIF4G domain DDE_1 PF03184.19 KSA03528.1 - 0.03 14.0 0.2 0.042 13.5 0.2 1.3 1 1 0 1 1 1 0 DDE superfamily endonuclease Vicilin_N PF04702.12 KSA03528.1 - 0.048 13.5 4.1 0.06 13.2 4.1 1.2 1 0 0 1 1 1 0 Vicilin N terminal region DUF676 PF05057.14 KSA03529.1 - 1.4e-38 132.6 0.2 2.5e-38 131.8 0.2 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 KSA03529.1 - 0.00016 21.6 0.0 0.00031 20.7 0.0 1.5 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Lipase_3 PF01764.25 KSA03529.1 - 0.0047 16.8 0.0 0.009 15.9 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) DLH PF01738.18 KSA03529.1 - 0.024 14.2 0.0 0.082 12.4 0.0 1.8 2 0 0 2 2 2 0 Dienelactone hydrolase family PGAP1 PF07819.13 KSA03529.1 - 0.026 14.3 0.0 0.073 12.8 0.0 1.8 2 0 0 2 2 2 0 PGAP1-like protein 7tm_1 PF00001.21 KSA03529.1 - 0.043 13.1 0.1 0.065 12.6 0.1 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) DUF3377 PF11857.8 KSA03529.1 - 0.083 12.8 0.4 0.33 10.9 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) Astro_capsid_p PF12226.8 KSA03529.1 - 7.9 5.5 11.0 12 4.9 11.0 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein ABC1 PF03109.16 KSA03530.1 - 2.3e-21 76.2 0.0 6.3e-14 52.2 0.0 2.7 1 1 1 2 2 2 2 ABC1 family RIO1 PF01163.22 KSA03530.1 - 0.0011 18.6 0.3 0.0043 16.7 0.1 2.1 2 0 0 2 2 2 1 RIO1 family Kelch_6 PF13964.6 KSA03531.1 - 0.00026 21.2 3.8 15 6.1 0.0 4.7 3 1 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 KSA03531.1 - 0.0084 16.1 3.1 0.43 10.6 0.1 4.5 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_5 PF13854.6 KSA03531.1 - 0.031 14.3 0.4 4.3 7.4 0.1 3.4 3 0 0 3 3 3 0 Kelch motif Kelch_1 PF01344.25 KSA03531.1 - 0.22 11.1 0.6 23 4.7 0.0 3.5 3 0 0 3 3 3 0 Kelch motif zf-Tim10_DDP PF02953.15 KSA03532.1 - 9.1e-20 70.1 4.3 1.1e-19 69.8 4.3 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Cyto_heme_lyase PF01265.17 KSA03533.1 - 1.1e-45 156.5 8.5 3.5e-45 154.8 8.5 1.7 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase SURF4 PF02077.15 KSA03534.1 - 5.2e-89 298.4 8.4 5.9e-89 298.2 8.4 1.0 1 0 0 1 1 1 1 SURF4 family MerC PF03203.14 KSA03534.1 - 0.31 11.5 13.6 0.24 11.9 4.1 2.5 1 1 2 3 3 3 0 MerC mercury resistance protein RNase_PH PF01138.21 KSA03535.1 - 5.6e-31 107.8 0.1 7.6e-31 107.4 0.1 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KSA03535.1 - 1.7e-05 24.7 0.1 3.3e-05 23.8 0.1 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Mannosyl_trans PF05007.13 KSA03536.1 - 4.9e-70 236.4 27.3 8.3e-70 235.6 27.3 1.4 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) HPD PF05044.12 KSA03536.1 - 0.015 15.1 0.5 0.027 14.4 0.5 1.3 1 0 0 1 1 1 0 Homeo-prospero domain GT87 PF09594.10 KSA03536.1 - 0.27 10.9 9.2 0.048 13.4 4.6 2.0 1 1 1 2 2 2 0 Glycosyltransferase family 87 DUF5572 PF17733.1 KSA03537.1 - 3.1e-23 81.3 1.0 6.1e-23 80.4 1.0 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5572) Mito_carr PF00153.27 KSA03538.1 - 8.5e-56 185.9 1.9 2.7e-19 68.9 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein TFIIF_alpha PF05793.12 KSA03539.1 - 6e-09 35.0 1.6 6e-09 35.0 1.6 4.8 1 1 2 4 4 4 2 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Alveol-reg_P311 PF11092.8 KSA03539.1 - 0.07 13.3 0.2 0.07 13.3 0.2 2.1 2 0 0 2 2 2 0 Neuronal protein 3.1 (p311) DUF383 PF04063.14 KSA03540.1 - 3.9e-69 232.1 0.5 3.9e-69 232.1 0.5 3.2 3 1 0 3 3 3 1 Domain of unknown function (DUF383) DUF384 PF04064.13 KSA03540.1 - 2e-22 78.8 5.7 7.5e-22 76.9 5.7 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF384) Peptidase_C50 PF03568.17 KSA03540.1 - 0.016 14.3 0.6 0.05 12.7 0.0 1.9 2 0 0 2 2 2 0 Peptidase family C50 MA3 PF02847.17 KSA03540.1 - 1.2 9.1 5.4 11 6.0 1.2 2.8 2 1 0 2 2 2 0 MA3 domain DUF4611 PF15387.6 KSA03540.1 - 1.3 9.3 6.8 1.5 9.1 5.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Peptidase_M20 PF01546.28 KSA03541.1 - 8.7e-31 107.2 0.0 1.6e-30 106.4 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KSA03541.1 - 5.3e-12 45.6 0.0 1.3e-11 44.4 0.0 1.7 1 1 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KSA03541.1 - 4.9e-05 23.1 0.0 0.00013 21.8 0.0 1.7 1 0 0 1 1 1 1 Peptidase family M28 TPP_enzyme_N PF02776.18 KSA03542.1 - 4.8e-32 110.9 0.0 8.9e-32 110.1 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 KSA03542.1 - 1.8e-23 82.8 0.0 1e-11 44.7 0.0 3.2 3 0 0 3 3 3 2 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 KSA03542.1 - 3.5e-13 49.6 0.0 6.6e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DC_STAMP PF07782.13 KSA03543.1 - 0.0011 18.8 0.1 0.0011 18.8 0.1 2.8 2 1 0 2 2 2 1 DC-STAMP-like protein Gpr1_Fun34_YaaH PF01184.19 KSA03543.1 - 0.006 16.2 7.0 0.006 16.2 7.0 2.6 3 0 0 3 3 3 1 GPR1/FUN34/yaaH family Tmemb_9 PF05434.11 KSA03543.1 - 0.044 13.7 1.2 0.1 12.5 0.3 2.0 2 0 0 2 2 2 0 TMEM9 DUF3377 PF11857.8 KSA03543.1 - 2.4 8.2 6.4 14 5.7 0.6 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF3377) GHMP_kinases_N PF00288.26 KSA03544.1 - 1.5e-13 50.8 0.8 3.1e-13 49.7 0.8 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KSA03544.1 - 1.2e-05 25.6 0.1 7.8e-05 23.0 0.1 2.4 1 1 0 1 1 1 1 GHMP kinases C terminal Fur_reg_FbpA PF13076.6 KSA03544.1 - 0.047 13.4 0.2 0.13 12.0 0.2 1.7 1 0 0 1 1 1 0 Fur-regulated basic protein A PDH PF02153.17 KSA03545.1 - 3.7e-12 45.8 0.0 5.6e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase 2-Hacid_dh_C PF02826.19 KSA03545.1 - 6.9e-06 25.5 0.0 1.4e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 KSA03545.1 - 9.4e-06 25.9 0.0 1.7e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KSA03545.1 - 0.00011 22.7 0.0 0.00033 21.2 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 KSA03545.1 - 0.003 17.2 0.0 0.0069 16.0 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 KSA03545.1 - 0.01 15.7 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 KSA03545.1 - 0.049 13.9 0.0 0.098 12.9 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 KSA03545.1 - 0.082 12.5 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Rossmann-like PF10727.9 KSA03545.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Rossmann-like domain IlvN PF07991.12 KSA03545.1 - 0.18 11.3 0.0 0.31 10.6 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Arf PF00025.21 KSA03546.1 - 2.1e-75 252.0 0.2 2.3e-75 251.8 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KSA03546.1 - 2.4e-16 60.0 0.0 3.2e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KSA03546.1 - 2.6e-11 43.3 0.0 3.1e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 KSA03546.1 - 2.3e-10 40.3 0.0 2.6e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 KSA03546.1 - 2.8e-10 39.9 0.5 4e-06 26.2 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 KSA03546.1 - 5.3e-10 39.0 0.0 6.6e-10 38.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KSA03546.1 - 0.0001 22.4 0.0 0.00015 21.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase MeaB PF03308.16 KSA03546.1 - 0.00054 19.0 0.8 0.016 14.2 0.1 2.5 2 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB GTP_EFTU PF00009.27 KSA03546.1 - 0.00081 19.0 0.1 0.0093 15.5 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 KSA03546.1 - 0.0029 18.1 0.3 0.0077 16.8 0.3 1.7 1 1 0 1 1 1 1 ABC transporter AAA_18 PF13238.6 KSA03546.1 - 0.048 14.2 0.2 0.08 13.5 0.2 1.5 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.22 KSA03546.1 - 0.12 11.9 0.4 0.64 9.6 0.1 2.0 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain IPP-2 PF04979.14 KSA03547.1 - 5.9e-19 69.1 10.6 5.9e-19 69.1 10.6 2.1 2 0 0 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) HA2 PF04408.23 KSA03547.1 - 2.9 8.2 6.6 8.3 6.8 0.4 2.3 2 0 0 2 2 2 0 Helicase associated domain (HA2) RAC_head PF16717.5 KSA03548.1 - 8.4e-24 84.4 5.1 8.4e-24 84.4 5.1 3.2 2 1 1 3 3 3 1 Ribosome-associated complex head domain DnaJ PF00226.31 KSA03548.1 - 5.6e-17 61.6 0.1 2.2e-16 59.7 0.1 2.1 1 0 0 1 1 1 1 DnaJ domain SPATA3 PF15662.5 KSA03548.1 - 0.26 11.9 4.7 0.42 11.2 4.7 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated protein 3 family Acyl-CoA_dh_1 PF00441.24 KSA03548.1 - 2.3 8.4 8.9 3.4 7.9 8.6 1.4 1 1 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain SBDS PF01172.18 KSA03549.1 - 2.4e-34 117.3 0.9 4.7e-34 116.3 0.9 1.5 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SBDS_C PF09377.10 KSA03549.1 - 1.5e-31 108.8 3.0 2.8e-31 107.9 3.0 1.5 1 0 0 1 1 1 1 SBDS protein C-terminal domain tRNA-synt_1b PF00579.25 KSA03550.1 - 1.6e-72 244.3 0.0 2.1e-72 243.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) YqzE PF14038.6 KSA03550.1 - 0.027 14.5 2.4 0.94 9.5 0.6 3.1 3 0 0 3 3 3 0 YqzE-like protein zf-UBR PF02207.20 KSA03551.1 - 4.8e-17 61.9 12.2 4.8e-17 61.9 12.2 2.7 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 KSA03551.1 - 2.7e-08 33.5 0.0 6.4e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS zf-C3HC4 PF00097.25 KSA03551.1 - 1.3e-05 25.0 1.0 6.3e-05 22.8 1.0 2.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF2113 PF09886.9 KSA03551.1 - 0.0052 16.2 0.3 0.011 15.1 0.3 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2113) zf-RING_2 PF13639.6 KSA03551.1 - 0.0056 17.0 0.6 0.0056 17.0 0.6 3.4 4 0 0 4 4 4 1 Ring finger domain zf-CpG_bind_C PF12269.8 KSA03551.1 - 0.21 11.3 8.4 2.2 8.0 0.8 2.4 2 0 0 2 2 2 0 CpG binding protein zinc finger C terminal domain zf_C2H2_13 PF18508.1 KSA03551.1 - 4 7.1 13.6 3.1 7.4 1.9 3.4 3 0 0 3 3 3 0 Zinc finger domain zf-C3HC4_2 PF13923.6 KSA03551.1 - 4.1 7.3 8.0 0.099 12.5 0.7 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-UBR PF02207.20 KSA03552.1 - 5.2e-16 58.6 16.8 2e-15 56.7 16.8 2.1 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 KSA03552.1 - 0.062 13.1 0.1 0.15 11.9 0.1 1.6 1 0 0 1 1 1 0 ATP-dependent Clp protease adaptor protein ClpS Rab5ip PF07019.12 KSA03553.1 - 9.4e-21 74.2 5.5 1e-20 74.1 5.5 1.0 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) SH3_1 PF00018.28 KSA03554.1 - 5.7e-25 86.7 6.7 4.4e-12 45.4 0.7 2.7 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 KSA03554.1 - 2.9e-24 84.6 2.9 5.1e-11 42.3 0.3 2.7 2 0 0 2 2 2 2 Variant SH3 domain Cofilin_ADF PF00241.20 KSA03554.1 - 1.2e-22 80.0 0.0 3.3e-22 78.6 0.0 1.8 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SH3_2 PF07653.17 KSA03554.1 - 1.6e-13 50.1 0.1 2.5e-05 23.9 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain DNA_pol_phi PF04931.13 KSA03554.1 - 6.3 4.8 21.5 0.087 10.9 10.8 2.4 2 0 0 2 2 2 0 DNA polymerase phi SPRY PF00622.28 KSA03556.1 - 1.2e-13 51.2 0.1 2.8e-13 50.0 0.1 1.6 2 0 0 2 2 2 1 SPRY domain TssO PF17561.2 KSA03556.1 - 0.1 12.7 2.0 0.2 11.8 2.0 1.4 1 0 0 1 1 1 0 Type VI secretion system, TssO Glyco_hydro_16 PF00722.21 KSA03557.1 - 1.5e-45 154.8 0.1 1.5e-45 154.8 0.1 2.3 2 1 0 2 2 2 1 Glycosyl hydrolases family 16 GREB1 PF15782.5 KSA03557.1 - 4.7 4.2 23.4 6.4 3.7 23.4 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SOG2 PF10428.9 KSA03557.1 - 5.1 6.2 36.2 8.2 5.5 36.2 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein SNF2_N PF00176.23 KSA03558.1 - 7.7e-67 225.5 0.7 1.3e-66 224.8 0.7 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KSA03558.1 - 5.9e-17 62.0 0.0 4.3e-16 59.2 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KSA03558.1 - 9.4e-07 28.8 0.0 2.2e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KSA03558.1 - 1.1e-06 28.8 1.2 4.1e-06 26.9 0.0 2.7 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_34 PF13872.6 KSA03558.1 - 0.0055 15.6 0.0 0.012 14.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 RNHCP PF12647.7 KSA03558.1 - 0.087 12.8 0.8 0.2 11.6 0.8 1.6 1 0 0 1 1 1 0 RNHCP domain Glyco_hydro_17 PF00332.18 KSA03559.1 - 2.7e-81 273.6 2.7 3.2e-81 273.3 2.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 WXG100 PF06013.12 KSA03559.1 - 0.18 12.1 1.9 5.7 7.2 0.8 2.5 2 0 0 2 2 2 0 Proteins of 100 residues with WXG Methyltrn_RNA_3 PF02598.17 KSA03560.1 - 1.7e-73 247.6 0.4 2e-73 247.4 0.4 1.0 1 0 0 1 1 1 1 Putative RNA methyltransferase Choline_kin_N PF04428.14 KSA03560.1 - 0.032 13.9 0.1 6.4 6.5 0.0 2.7 2 0 0 2 2 2 0 Choline kinase N terminus APG6_N PF17675.1 KSA03561.1 - 0.0044 17.6 8.0 0.0044 17.6 8.0 5.1 2 1 2 4 4 4 3 Apg6 coiled-coil region DivIC PF04977.15 KSA03561.1 - 0.0081 15.9 2.5 0.0081 15.9 2.5 7.2 3 3 5 8 8 8 1 Septum formation initiator NUDIX PF00293.28 KSA03562.1 - 1.4e-20 73.7 0.0 3e-20 72.6 0.0 1.6 1 1 0 1 1 1 1 NUDIX domain LIAS_N PF16881.5 KSA03563.1 - 2.2e-21 76.3 0.4 7.2e-21 74.6 0.1 1.9 2 0 0 2 2 2 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 KSA03563.1 - 7.7e-13 49.2 0.0 1.3e-12 48.4 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Spore_GerAC PF05504.11 KSA03563.1 - 0.03 14.6 0.0 0.054 13.7 0.0 1.4 1 0 0 1 1 1 0 Spore germination B3/ GerAC like, C-terminal Hist_deacetyl PF00850.19 KSA03564.1 - 1.4e-51 175.9 0.3 4.3e-50 170.9 0.0 2.4 2 1 0 2 2 2 1 Histone deacetylase domain DUF4116 PF13475.6 KSA03564.1 - 0.0042 16.8 0.9 0.28 11.0 0.0 3.5 3 0 0 3 3 3 1 Domain of unknown function (DUF4116) SF3A3 PF16837.5 KSA03564.1 - 0.077 13.5 5.5 0.23 12.0 5.5 1.8 1 0 0 1 1 1 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 RhoGAP PF00620.27 KSA03565.1 - 8.7e-32 110.0 0.0 2.8e-31 108.4 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain PH PF00169.29 KSA03565.1 - 2.6e-11 44.0 0.3 1.2e-10 41.9 0.0 2.3 2 0 0 2 2 2 1 PH domain PX PF00787.24 KSA03565.1 - 2.1e-09 37.4 0.0 8.9e-09 35.3 0.0 2.1 1 0 0 1 1 1 1 PX domain PH_11 PF15413.6 KSA03565.1 - 0.018 15.5 0.0 0.11 12.9 0.0 2.5 1 1 0 1 1 1 0 Pleckstrin homology domain CorC_HlyC PF03471.17 KSA03565.1 - 0.17 12.0 0.0 0.4 10.7 0.0 1.6 1 0 0 1 1 1 0 Transporter associated domain RNA_pol_Rpb1_R PF05001.13 KSA03565.1 - 4.3 7.9 6.0 12 6.5 6.0 1.8 1 0 0 1 1 1 0 RNA polymerase Rpb1 C-terminal repeat GAS PF13851.6 KSA03565.1 - 9 5.6 18.6 0.21 10.9 4.7 3.0 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding TFIIA PF03153.13 KSA03566.1 - 1.8e-52 179.7 26.9 1.7e-29 104.1 24.5 2.0 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit Afi1 PF07792.12 KSA03566.1 - 0.037 14.5 6.1 0.077 13.5 6.1 1.5 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DNA_pol_phi PF04931.13 KSA03566.1 - 0.16 10.1 13.9 0.2 9.7 13.9 1.2 1 0 0 1 1 1 0 DNA polymerase phi PPP4R2 PF09184.11 KSA03566.1 - 0.32 10.6 12.1 0.44 10.1 12.1 1.2 1 0 0 1 1 1 0 PPP4R2 Nop14 PF04147.12 KSA03566.1 - 1.6 6.8 11.2 1.9 6.6 11.2 1.1 1 0 0 1 1 1 0 Nop14-like family Fungal_TACC PF12709.7 KSA03567.1 - 2e-23 82.6 9.2 2e-23 82.6 9.2 10.2 4 1 7 11 11 11 1 Fungal Transforming acidic coiled-coil (TACC) proteins Filament PF00038.21 KSA03567.1 - 0.0014 18.3 86.7 0.057 13.0 50.5 4.3 2 2 2 4 4 4 2 Intermediate filament protein BST2 PF16716.5 KSA03567.1 - 0.0042 17.6 12.6 0.0042 17.6 12.6 7.4 3 2 5 8 8 8 2 Bone marrow stromal antigen 2 Lebercilin PF15619.6 KSA03567.1 - 0.0079 15.9 22.6 0.0079 15.9 22.6 5.5 2 2 3 5 5 5 3 Ciliary protein causing Leber congenital amaurosis disease DUF1664 PF07889.12 KSA03567.1 - 0.015 15.3 4.3 0.015 15.3 4.3 6.9 1 1 4 6 6 6 0 Protein of unknown function (DUF1664) HIP1_clath_bdg PF16515.5 KSA03567.1 - 0.019 15.5 3.7 0.019 15.5 3.7 8.5 2 1 7 9 9 9 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Pro_3_hydrox_C PF05373.11 KSA03567.1 - 0.054 13.6 1.8 1.8 8.7 0.2 3.3 2 0 0 2 2 2 0 L-proline 3-hydroxylase, C-terminal MbeD_MobD PF04899.12 KSA03567.1 - 1.4 9.1 16.3 0.61 10.2 0.9 4.5 4 1 1 5 5 5 0 MbeD/MobD like DUF3450 PF11932.8 KSA03567.1 - 7.4 5.8 73.5 0.53 9.5 5.0 6.2 1 1 5 6 6 6 0 Protein of unknown function (DUF3450) Peptidase_M20 PF01546.28 KSA03569.1 - 1.9e-32 112.7 0.0 2.6e-32 112.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KSA03569.1 - 9.6e-11 41.6 0.0 4.6e-10 39.4 0.0 2.0 1 1 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KSA03569.1 - 4.1e-05 23.4 0.0 9e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KSA03570.1 - 5.1e-33 114.5 0.0 8.2e-33 113.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KSA03570.1 - 1.2e-10 41.2 0.0 2.7e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KSA03570.1 - 1.4e-05 24.8 0.0 4.6e-05 23.2 0.0 1.8 1 1 0 1 1 1 1 Peptidase family M28 He_PIG PF05345.12 KSA03570.1 - 0.017 15.3 0.6 0.042 14.0 0.1 2.0 2 0 0 2 2 2 0 Putative Ig domain RNA_pol_N PF01194.17 KSA03571.1 - 2e-30 104.8 0.9 2.4e-30 104.6 0.9 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit WD40 PF00400.32 KSA03572.1 - 0.0091 16.8 0.0 0.0091 16.8 0.0 5.1 6 0 0 6 6 6 1 WD domain, G-beta repeat Dynamin_N PF00350.23 KSA03573.1 - 2.2e-42 145.0 1.0 8.8e-42 143.0 0.0 2.5 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 KSA03573.1 - 1.7e-05 24.9 0.0 6.7e-05 22.9 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_M PF01031.20 KSA03573.1 - 0.033 13.4 9.5 0.016 14.4 3.0 3.2 3 1 0 3 3 3 0 Dynamin central region AAA_16 PF13191.6 KSA03573.1 - 0.033 14.6 0.0 0.1 13.0 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain TniB PF05621.11 KSA03573.1 - 0.058 12.8 0.0 0.14 11.6 0.0 1.6 1 0 0 1 1 1 0 Bacterial TniB protein DUF5111 PF17138.4 KSA03573.1 - 0.067 13.0 0.0 1.1 9.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5111) DAGK_prokar PF01219.19 KSA03573.1 - 0.079 12.8 0.1 0.18 11.7 0.1 1.5 1 0 0 1 1 1 0 Prokaryotic diacylglycerol kinase NOA36 PF06524.12 KSA03573.1 - 4 6.7 13.2 8.5 5.6 13.2 1.5 1 0 0 1 1 1 0 NOA36 protein Gln-synt_C PF00120.24 KSA03574.1 - 2.6e-21 76.0 0.0 7.9e-17 61.3 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 KSA03574.1 - 1.8e-12 46.8 0.0 4.1e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain V-ATPase_H_N PF03224.14 KSA03575.1 - 2.8e-72 243.7 18.3 2.8e-72 243.7 18.3 1.6 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 KSA03575.1 - 1.6e-29 102.4 1.1 1.6e-29 102.4 1.1 3.0 3 1 0 3 3 3 1 V-ATPase subunit H BIR PF00653.21 KSA03576.1 - 7.5e-33 113.0 6.7 3e-20 72.6 1.3 2.7 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain SAPS PF04499.15 KSA03577.1 - 3.7e-163 543.8 7.2 3.7e-163 543.8 7.2 2.6 3 0 0 3 3 3 2 SIT4 phosphatase-associated protein DnaJ PF00226.31 KSA03578.1 - 2.7e-13 49.8 0.0 5.1e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain MFS_1 PF07690.16 KSA03580.1 - 2.1e-27 96.0 43.2 1.2e-23 83.6 24.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KSA03580.1 - 2.2e-06 26.8 36.6 0.00013 20.9 20.6 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MRP_L53 PF10780.9 KSA03581.1 - 2.1e-18 66.2 0.5 3.3e-18 65.6 0.5 1.3 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 VraX PF17412.2 KSA03581.1 - 0.057 13.1 0.3 1 9.0 0.1 2.3 2 0 0 2 2 2 0 Family of unknown function RAI1 PF08652.11 KSA03582.1 - 2.1e-12 47.0 0.1 6e-12 45.6 0.1 1.8 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease 2-Hacid_dh_C PF02826.19 KSA03583.1 - 9.7e-43 145.6 0.0 3.9e-42 143.6 0.0 1.9 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KSA03583.1 - 5.7e-19 68.1 0.0 7.8e-19 67.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Shikimate_DH PF01488.20 KSA03583.1 - 0.084 12.9 0.2 0.45 10.6 0.0 2.2 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Fer2_3 PF13085.6 KSA03584.1 - 2.9e-32 110.9 0.1 4.8e-32 110.2 0.1 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 KSA03584.1 - 2.2e-09 37.7 8.5 2.2e-09 37.7 8.5 2.2 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 KSA03584.1 - 3.8e-08 33.7 24.4 2e-07 31.3 9.4 2.5 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 KSA03584.1 - 3.1e-07 30.4 3.7 3.1e-07 30.4 3.7 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 KSA03584.1 - 0.00077 20.0 5.2 0.00077 20.0 5.2 2.7 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 KSA03584.1 - 0.0039 17.1 1.7 0.0039 17.1 1.7 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_9 PF13187.6 KSA03584.1 - 0.32 11.2 13.3 0.2 11.9 8.6 2.6 2 1 0 2 2 2 0 4Fe-4S dicluster domain DHDPS PF00701.22 KSA03585.1 - 1.5e-36 125.6 0.0 1.8e-36 125.3 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Methyltransf_31 PF13847.6 KSA03586.1 - 4.6e-27 94.7 0.0 5.7e-27 94.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KSA03586.1 - 6.8e-24 84.3 0.0 1.2e-23 83.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KSA03586.1 - 8.8e-23 80.8 0.0 1.5e-22 80.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KSA03586.1 - 1.6e-17 63.6 0.0 2.3e-17 63.2 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KSA03586.1 - 3.1e-13 49.9 0.0 5.3e-13 49.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KSA03586.1 - 6.9e-13 49.2 0.0 1e-12 48.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 KSA03586.1 - 1.1e-07 31.6 0.0 1.6e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PCMT PF01135.19 KSA03586.1 - 2.1e-07 30.9 0.0 3e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_9 PF08003.11 KSA03586.1 - 2.3e-07 30.0 0.0 3.5e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_29 PF03141.16 KSA03586.1 - 6.8e-07 28.2 0.1 2.4e-06 26.4 0.0 1.7 2 0 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_4 PF02390.17 KSA03586.1 - 2.8e-05 23.7 0.0 6.8e-05 22.4 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.14 KSA03586.1 - 0.0001 21.9 0.0 0.00016 21.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_PK PF05891.12 KSA03586.1 - 0.0003 20.4 0.0 0.00056 19.5 0.0 1.4 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase NodS PF05401.11 KSA03586.1 - 0.00087 18.9 0.0 0.0012 18.5 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) TehB PF03848.14 KSA03586.1 - 0.0026 17.2 0.0 0.0047 16.3 0.0 1.5 1 1 0 1 1 1 1 Tellurite resistance protein TehB RrnaAD PF00398.20 KSA03586.1 - 0.0067 15.5 0.0 0.0094 15.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase DREV PF05219.12 KSA03586.1 - 0.0098 15.0 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase CMAS PF02353.20 KSA03586.1 - 0.012 15.0 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.6 KSA03586.1 - 0.043 13.8 0.0 0.062 13.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain CheR PF01739.18 KSA03586.1 - 0.079 12.4 0.0 0.29 10.6 0.0 1.8 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain SepRS_C PF18006.1 KSA03586.1 - 0.11 12.6 0.0 0.36 11.0 0.1 1.9 2 0 0 2 2 2 0 O-phosphoseryl-tRNA synthetase C-terminal domain UPF0020 PF01170.18 KSA03586.1 - 0.12 12.1 0.2 5.9 6.5 0.0 3.0 3 1 0 3 3 3 0 Putative RNA methylase family UPF0020 Methyltransf_18 PF12847.7 KSA03586.1 - 0.12 12.3 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain D-ser_dehydrat PF14031.6 KSA03587.1 - 5.3e-22 78.3 0.0 4.5e-21 75.3 0.0 2.1 2 0 0 2 2 2 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 KSA03587.1 - 9.9e-12 45.0 0.0 1.3e-11 44.6 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Abhydrolase_3 PF07859.13 KSA03588.1 - 2.7e-63 213.6 0.0 3.5e-63 213.3 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KSA03588.1 - 2.3e-06 26.8 0.1 5.8e-06 25.5 0.0 1.6 2 0 0 2 2 2 1 Carboxylesterase family Peptidase_S9 PF00326.21 KSA03588.1 - 8.5e-06 25.4 0.0 0.00065 19.2 0.0 2.3 1 1 0 1 1 1 1 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 KSA03588.1 - 0.004 16.1 0.0 0.0074 15.2 0.0 1.3 1 1 0 1 1 1 1 Steryl acetyl hydrolase Esterase_phd PF10503.9 KSA03588.1 - 0.16 11.4 0.0 0.33 10.4 0.0 1.4 1 0 0 1 1 1 0 Esterase PHB depolymerase Fungal_trans PF04082.18 KSA03589.1 - 5.1e-73 245.4 3.8 9e-73 244.6 3.8 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KSA03589.1 - 6.5e-07 29.5 7.3 0.00019 21.7 1.1 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KSA03589.1 - 0.00075 19.7 1.1 0.0024 18.1 1.1 1.9 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KSA03589.1 - 0.0015 19.2 5.4 0.013 16.3 0.4 3.1 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KSA03589.1 - 0.0063 16.5 0.0 0.017 15.1 0.0 1.8 1 0 0 1 1 1 1 C2H2-type zinc finger FOXP-CC PF16159.5 KSA03589.1 - 0.078 13.6 0.2 0.078 13.6 0.2 2.1 2 0 0 2 2 2 0 FOXP coiled-coil domain Ribonuc_L-PSP PF01042.21 KSA03590.1 - 1.2e-21 77.0 0.0 1.4e-21 76.7 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP MFS_1 PF07690.16 KSA03591.1 - 2.8e-30 105.4 21.1 2.8e-30 105.4 21.1 2.0 1 1 0 2 2 2 2 Major Facilitator Superfamily RRM_1 PF00076.22 KSA03592.1 - 7.8e-07 28.8 0.1 1.8e-06 27.6 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mito_carr PF00153.27 KSA03593.1 - 2e-69 229.5 0.9 1.7e-23 82.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RAG1 PF12940.7 KSA03593.1 - 0.13 10.3 0.0 0.17 9.9 0.0 1.1 1 0 0 1 1 1 0 Recombination-activation protein 1 (RAG1), recombinase Scramblase PF03803.15 KSA03594.1 - 1.3e-61 207.7 0.0 1.8e-61 207.3 0.0 1.1 1 0 0 1 1 1 1 Scramblase DUF4298 PF14131.6 KSA03594.1 - 0.0064 16.4 0.1 0.012 15.5 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4298) Peptidase_C12 PF01088.21 KSA03595.1 - 9.2e-57 192.2 0.0 1.2e-56 191.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 KSA03595.1 - 1.6e-10 40.7 0.1 3.6e-10 39.6 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases PET122 PF05476.11 KSA03595.1 - 0.0072 15.7 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 PET122 Metallophos PF00149.28 KSA03596.1 - 1.2e-33 117.4 1.0 2e-33 116.6 1.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Aminotran_3 PF00202.21 KSA03597.1 - 1.6e-116 389.3 0.0 2e-116 389.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Cation_efflux PF01545.21 KSA03598.1 - 7.6e-09 35.6 9.6 1.3e-08 34.9 9.6 1.3 1 0 0 1 1 1 1 Cation efflux family Med12 PF09497.10 KSA03599.1 - 2.3e-22 79.0 0.4 7.7e-22 77.4 0.4 2.0 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 Myosin_head PF00063.21 KSA03600.1 - 1.9e-229 763.4 6.2 2.4e-229 763.0 6.2 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 KSA03600.1 - 2.1e-50 171.0 0.0 4.4e-50 170.0 0.0 1.6 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_1 PF00018.28 KSA03600.1 - 2.8e-11 42.8 0.2 5.3e-11 41.9 0.2 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KSA03600.1 - 1e-08 34.9 0.0 2.4e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KSA03600.1 - 4.8e-06 26.2 0.0 5.6e-05 22.7 0.0 2.3 2 0 0 2 2 2 1 Variant SH3 domain Hpr_kinase_C PF07475.12 KSA03600.1 - 0.0024 17.4 0.7 1 8.9 0.1 2.4 2 0 0 2 2 2 2 HPr Serine kinase C-terminal domain RsgA_GTPase PF03193.16 KSA03600.1 - 0.0072 16.2 0.0 0.023 14.6 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KSA03600.1 - 0.048 14.0 0.0 0.16 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KSA03600.1 - 0.13 12.6 0.0 0.48 10.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KSA03600.1 - 0.13 12.2 0.0 0.45 10.4 0.0 2.0 2 0 0 2 2 2 0 NACHT domain WD40 PF00400.32 KSA03601.1 - 1.2e-57 190.5 40.6 8.9e-11 42.2 0.4 9.1 8 1 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KSA03601.1 - 6.3e-16 58.5 5.4 0.0024 18.1 0.1 6.1 4 2 3 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain NLE PF08154.12 KSA03601.1 - 6.2e-11 42.7 0.0 1.2e-10 41.7 0.0 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain eIF2A PF08662.11 KSA03601.1 - 1.5e-07 31.5 0.2 0.00044 20.2 0.0 3.7 2 2 2 4 4 4 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KSA03601.1 - 2.9e-06 26.5 0.7 2.2 7.2 0.0 4.8 3 2 2 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KSA03601.1 - 0.00064 18.5 10.0 0.52 8.9 0.1 4.7 4 2 2 6 6 6 2 Nucleoporin Nup120/160 Frtz PF11768.8 KSA03601.1 - 0.0081 14.5 0.0 3.5 5.8 0.0 2.6 3 0 0 3 3 3 2 WD repeat-containing and planar cell polarity effector protein Fritz Nucleoporin_N PF08801.11 KSA03601.1 - 0.011 14.5 1.8 0.26 10.0 0.8 2.8 2 1 0 2 2 2 0 Nup133 N terminal like Cytochrom_D1 PF02239.16 KSA03601.1 - 0.037 12.6 0.1 0.36 9.3 0.1 2.2 1 1 1 2 2 2 0 Cytochrome D1 heme domain WD40_like PF17005.5 KSA03601.1 - 0.067 12.5 0.0 1.4 8.2 0.0 2.9 3 1 1 4 4 4 0 WD40-like domain PD40 PF07676.12 KSA03601.1 - 0.22 11.5 0.9 1.8 8.6 0.1 2.9 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Hira PF07569.11 KSA03601.1 - 0.31 10.7 2.0 17 5.1 0.5 2.6 2 0 0 2 2 2 0 TUP1-like enhancer of split Pkinase PF00069.25 KSA03603.1 - 2e-66 224.1 0.0 3.8e-66 223.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KSA03603.1 - 7.4e-35 120.5 0.0 2.8e-24 85.8 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KSA03603.1 - 0.0004 19.8 0.2 0.0023 17.3 0.2 2.1 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 KSA03603.1 - 0.0084 16.1 0.1 0.041 13.8 0.1 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KSA03603.1 - 0.082 12.3 0.1 0.19 11.1 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RPT PF13446.6 KSA03603.1 - 0.1 12.6 0.3 9.7 6.2 0.3 3.1 2 0 0 2 2 2 0 A repeated domain in UCH-protein Img2 PF05046.14 KSA03604.1 - 1e-16 61.0 0.6 1.2e-16 60.7 0.6 1.1 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) zf-H2C2_2 PF13465.6 KSA03605.1 - 2.4e-20 71.9 27.3 2.7e-08 33.9 0.2 7.6 7 0 0 7 7 6 4 Zinc-finger double domain zf-C2H2 PF00096.26 KSA03605.1 - 2.4e-17 62.3 41.0 6.1e-05 23.3 0.4 7.8 7 0 0 7 7 7 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KSA03605.1 - 4.4e-07 30.2 52.9 0.0069 17.1 0.8 9.3 9 0 0 9 9 8 4 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KSA03605.1 - 1.2e-06 28.4 19.3 0.0056 16.7 0.2 5.7 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KSA03605.1 - 1.7e-05 24.6 3.9 1.5 8.8 0.1 4.9 4 0 0 4 4 4 1 zinc-finger of a C2HC-type Zap1_zf2 PF18217.1 KSA03605.1 - 0.0008 19.3 8.4 0.0008 19.3 8.4 4.8 5 0 0 5 5 4 1 Zap1 zinc finger 2 FOXP-CC PF16159.5 KSA03605.1 - 0.00088 19.9 0.2 0.00088 19.9 0.2 7.3 6 2 2 8 8 7 2 FOXP coiled-coil domain zf-C2H2_11 PF16622.5 KSA03605.1 - 0.0014 18.4 15.1 0.0073 16.0 0.7 4.4 3 1 1 4 4 4 2 zinc-finger C2H2-type RYDR_ITPR PF01365.21 KSA03605.1 - 0.3 10.5 5.3 5.8 6.3 0.0 3.0 4 0 0 4 4 4 0 RIH domain LIM PF00412.22 KSA03605.1 - 0.37 11.1 16.0 0.75 10.1 3.2 4.5 3 1 1 4 4 4 0 LIM domain zf-met PF12874.7 KSA03605.1 - 0.65 10.5 23.5 0.39 11.2 0.2 6.1 6 0 0 6 6 6 0 Zinc-finger of C2H2 type DUF3910 PF13049.6 KSA03606.1 - 0.17 12.2 0.9 1.4 9.3 0.9 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3910) PAT1 PF09770.9 KSA03607.1 - 1.5e-107 361.0 87.1 1e-96 325.2 67.3 4.1 1 1 1 2 2 2 2 Topoisomerase II-associated protein PAT1 Ubiquitin_3 PF14836.6 KSA03607.1 - 0.021 14.8 0.0 0.077 13.0 0.0 2.0 1 0 0 1 1 1 0 Ubiquitin-like domain MDM10 PF12519.8 KSA03607.1 - 7 5.4 12.9 14 4.4 12.9 1.4 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 FHIPEP PF00771.20 KSA03607.1 - 9.8 4.5 9.7 20 3.5 9.7 1.4 1 0 0 1 1 1 0 FHIPEP family Chorismate_bind PF00425.18 KSA03608.1 - 6.1e-76 255.4 0.0 9.5e-76 254.8 0.0 1.3 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.28 KSA03608.1 - 1.6e-29 103.1 0.0 3.3e-29 102.0 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 KSA03608.1 - 8.6e-18 64.9 0.0 2.1e-17 63.6 0.0 1.7 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 KSA03608.1 - 1.2e-05 25.2 0.0 4.3e-05 23.4 0.0 2.0 1 1 0 1 1 1 1 Peptidase C26 Uso1_p115_head PF04869.14 KSA03609.1 - 2e-113 378.6 3.8 1.1e-112 376.2 0.9 3.0 2 0 0 2 2 2 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.13 KSA03609.1 - 2.3e-07 31.2 65.7 2.3e-07 31.2 65.7 18.2 2 1 16 19 19 19 2 Uso1 / p115 like vesicle tethering protein, C terminal region HEAT_2 PF13646.6 KSA03609.1 - 0.00046 20.5 1.2 0.071 13.5 0.1 3.4 3 0 0 3 3 3 1 HEAT repeats Arm_vescicular PF18770.1 KSA03609.1 - 0.0013 18.6 0.3 0.0044 16.9 0.2 1.9 2 0 0 2 2 2 1 Armadillo tether-repeat of vescicular transport factor TMF_TATA_bd PF12325.8 KSA03609.1 - 0.0024 18.1 16.9 0.0024 18.1 16.9 15.6 3 3 11 14 14 14 3 TATA element modulatory factor 1 TATA binding TPR_MLP1_2 PF07926.12 KSA03609.1 - 0.0065 16.5 19.2 0.0065 16.5 19.2 15.9 1 1 11 15 15 15 7 TPR/MLP1/MLP2-like protein HEAT_EZ PF13513.6 KSA03609.1 - 0.016 15.7 0.4 0.65 10.6 0.1 3.3 2 1 1 3 3 3 0 HEAT-like repeat HEAT PF02985.22 KSA03609.1 - 0.55 10.6 1.8 5.6 7.5 0.1 3.6 4 0 0 4 4 4 0 HEAT repeat GAS PF13851.6 KSA03609.1 - 3.8 6.8 298.4 0.0069 15.8 24.3 13.1 1 1 11 12 12 12 0 Growth-arrest specific micro-tubule binding Filament PF00038.21 KSA03609.1 - 5.5 6.5 245.4 0.048 13.3 43.0 9.0 1 1 8 10 10 10 0 Intermediate filament protein Rad52_Rad22 PF04098.15 KSA03610.1 - 8.8e-13 48.4 0.1 1.3e-12 47.9 0.1 1.2 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein IKI3 PF04762.12 KSA03611.1 - 0 1204.6 0.6 0 1204.3 0.6 1.1 1 0 0 1 1 1 1 IKI3 family ANAPC4_WD40 PF12894.7 KSA03611.1 - 0.0053 17.0 0.0 1.4e+02 2.9 0.0 4.9 4 1 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain DUF928 PF06051.12 KSA03611.1 - 0.056 13.3 0.3 0.48 10.3 0.1 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF928) IF-2B PF01008.17 KSA03611.1 - 0.077 12.2 0.1 0.35 10.0 0.0 2.0 2 0 0 2 2 2 0 Initiation factor 2 subunit family REV PF00424.18 KSA03611.1 - 0.17 11.9 0.0 0.17 11.9 0.0 3.3 2 1 1 3 3 3 0 REV protein (anti-repression trans-activator protein) V_ATPase_I PF01496.19 KSA03612.1 - 0 1025.7 6.7 0 1025.3 6.7 1.2 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Herpes_gE PF02480.16 KSA03612.1 - 0.03 13.1 0.0 0.047 12.4 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E RIX1 PF08167.12 KSA03613.1 - 2.7e-44 151.2 2.3 2.7e-44 151.2 2.3 3.0 3 0 0 3 3 3 1 rRNA processing/ribosome biogenesis CD47 PF04549.14 KSA03613.1 - 0.091 13.0 0.4 0.19 11.9 0.4 1.5 1 0 0 1 1 1 0 CD47 transmembrane region PAH PF02671.21 KSA03613.1 - 0.13 12.4 1.9 5.4 7.2 0.0 3.7 3 1 0 3 3 3 0 Paired amphipathic helix repeat ANAPC5 PF12862.7 KSA03614.1 - 1.9e-30 104.8 5.7 1.9e-30 104.8 5.7 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 5 TPR_MalT PF17874.1 KSA03614.1 - 0.00028 20.4 0.2 0.004 16.6 0.2 2.2 2 0 0 2 2 2 1 MalT-like TPR region TPR_12 PF13424.6 KSA03614.1 - 0.0053 17.0 3.6 11 6.4 0.0 4.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_15 PF13429.6 KSA03614.1 - 0.02 14.1 3.6 7.1 5.7 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat NRDE-2 PF08424.10 KSA03614.1 - 2 7.4 7.6 1.3 8.0 0.4 2.5 3 0 0 3 3 3 0 NRDE-2, necessary for RNA interference CDP-OH_P_transf PF01066.21 KSA03615.1 - 6.2e-12 46.1 0.4 6.2e-12 46.1 0.4 2.7 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF4181 PF13789.6 KSA03615.1 - 0.001 19.3 1.5 0.048 13.9 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4181) Epimerase PF01370.21 KSA03616.1 - 2.7e-23 82.7 0.0 3.6e-23 82.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KSA03616.1 - 1.6e-20 73.3 0.0 2.1e-20 72.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KSA03616.1 - 1.5e-17 63.7 0.0 1.9e-17 63.3 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 KSA03616.1 - 1.2e-16 61.0 0.0 3.2e-16 59.6 0.0 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KSA03616.1 - 1.2e-09 38.4 0.0 1e-08 35.3 0.0 2.6 1 1 1 2 2 2 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KSA03616.1 - 1.3e-09 37.6 0.0 2.6e-06 26.8 0.0 2.1 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein NmrA PF05368.13 KSA03616.1 - 6.1e-07 29.2 0.0 0.0001 21.9 0.0 2.2 2 0 0 2 2 2 2 NmrA-like family KR PF08659.10 KSA03616.1 - 0.00069 19.6 0.1 0.0025 17.8 0.1 1.9 1 1 0 1 1 1 1 KR domain adh_short PF00106.25 KSA03616.1 - 0.0018 17.8 0.1 0.01 15.3 0.1 2.0 2 0 0 2 2 2 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 KSA03616.1 - 0.045 12.8 0.0 0.54 9.3 0.0 2.1 2 0 0 2 2 2 0 RmlD substrate binding domain ApbA PF02558.16 KSA03616.1 - 0.049 13.3 0.0 0.093 12.4 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA PGBA_C PF15437.6 KSA03616.1 - 1.3 9.4 5.0 11 6.5 0.5 2.3 2 0 0 2 2 2 0 Plasminogen-binding protein pgbA C-terminal His_Phos_2 PF00328.22 KSA03617.1 - 4.6e-58 197.4 0.0 5.5e-58 197.2 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DNA_pol_B PF00136.21 KSA03618.1 - 4.7e-97 325.6 1.8 6.8e-97 325.0 1.8 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 KSA03618.1 - 1.4e-26 93.5 10.2 5.4e-14 52.1 3.3 2.5 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 KSA03618.1 - 0.063 13.8 15.1 0.16 12.5 15.1 1.7 1 0 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta Pkinase PF00069.25 KSA03619.1 - 1.9e-60 204.5 0.0 3.2e-60 203.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KSA03619.1 - 1.5e-37 129.3 0.0 2.4e-37 128.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KSA03619.1 - 5.5e-07 29.2 0.0 9.3e-07 28.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 KSA03619.1 - 0.0018 17.4 0.1 0.0032 16.6 0.1 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Pkinase_fungal PF17667.1 KSA03619.1 - 0.0046 15.8 0.1 0.012 14.4 0.1 1.9 1 1 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KSA03619.1 - 1.2 8.0 7.9 0.34 9.8 0.0 2.5 2 0 0 2 2 2 0 Haspin like kinase domain Sds3 PF08598.11 KSA03619.1 - 7.8 6.4 8.7 0.45 10.5 0.5 2.3 2 0 0 2 2 2 0 Sds3-like P34-Arc PF04045.14 KSA03620.1 - 2e-108 361.6 2.4 2.7e-108 361.2 2.4 1.2 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc ARPC4 PF05856.12 KSA03620.1 - 0.0075 15.9 0.6 0.013 15.1 0.6 1.4 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) EF-hand_6 PF13405.6 KSA03620.1 - 0.28 11.2 2.4 0.62 10.1 0.1 2.9 3 0 0 3 3 3 0 EF-hand domain Ribosom_S12_S23 PF00164.25 KSA03621.1 - 5.5e-33 113.0 1.1 8e-33 112.5 1.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Ribosomal_S12 PF17487.2 KSA03621.1 - 0.09 13.5 0.0 0.18 12.5 0.0 1.5 1 1 0 1 1 1 0 Ribosomal protein S12 Mob_synth_C PF06463.13 KSA03621.1 - 0.16 11.9 0.1 0.25 11.3 0.1 1.4 1 1 0 1 1 1 0 Molybdenum Cofactor Synthesis C PP-binding PF00550.25 KSA03622.1 - 2.4e-12 47.0 0.3 3.1e-12 46.7 0.3 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 KSA03622.1 - 7.1e-06 26.2 0.4 9.7e-06 25.7 0.4 1.2 1 0 0 1 1 1 1 Acyl-carrier DUF1493 PF07377.12 KSA03622.1 - 0.15 12.5 0.5 0.22 12.0 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) QCR10 PF09796.9 KSA03623.1 - 4.2e-21 74.8 0.4 4.8e-21 74.6 0.4 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) UCR_6-4kD PF08997.10 KSA03623.1 - 0.063 13.2 0.1 0.12 12.4 0.1 1.6 1 1 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein Cullin PF00888.22 KSA03624.1 - 2.3e-70 238.0 31.9 3.1e-70 237.5 31.9 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KSA03624.1 - 5.2e-14 52.0 0.1 5.2e-14 52.0 0.1 2.7 3 0 0 3 3 3 1 Cullin protein neddylation domain LRR_3 PF07725.12 KSA03624.1 - 0.082 12.8 0.5 17 5.5 0.0 3.0 2 0 0 2 2 2 0 Leucine Rich Repeat COMPASS-Shg1 PF05205.12 KSA03625.1 - 2e-27 95.9 6.7 2e-27 95.9 6.7 2.1 2 1 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component shg1 RhoGAP PF00620.27 KSA03626.1 - 8.2e-43 145.9 0.9 2.3e-42 144.4 0.0 2.2 3 0 0 3 3 3 1 RhoGAP domain FCH PF00611.23 KSA03626.1 - 7.1e-10 39.0 0.3 3.4e-09 36.8 0.3 2.2 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain Chs7 PF12271.8 KSA03627.1 - 1.5e-120 401.9 25.8 1.7e-120 401.8 25.8 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone DUF4549 PF15082.6 KSA03628.1 - 0.53 10.1 2.2 1.8 8.4 0.3 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4549) GSHPx PF00255.19 KSA03629.1 - 6.9e-43 144.6 0.5 8.9e-43 144.3 0.5 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 KSA03629.1 - 0.00019 21.3 0.0 0.00029 20.7 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KSA03629.1 - 0.001 18.8 0.0 0.002 17.8 0.0 1.5 2 0 0 2 2 2 1 Redoxin SNF2_N PF00176.23 KSA03630.1 - 3e-76 256.4 0.1 6.1e-76 255.4 0.1 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 KSA03630.1 - 3.2e-40 136.7 0.9 3.2e-40 136.7 0.9 3.2 3 0 0 3 3 3 1 SLIDE HAND PF09110.11 KSA03630.1 - 6.1e-32 110.7 4.6 6.1e-32 110.7 4.6 3.4 4 0 0 4 4 3 1 HAND Helicase_C PF00271.31 KSA03630.1 - 2.2e-18 66.6 0.0 8.5e-18 64.7 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KSA03630.1 - 1.4e-10 41.5 2.2 3.2e-10 40.3 0.0 2.9 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KSA03630.1 - 7.2e-06 25.4 0.0 8.4e-05 21.9 0.2 2.5 1 1 1 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 SWI2_SNF2 PF18766.1 KSA03630.1 - 0.00012 21.9 0.0 0.00054 19.7 0.0 2.2 1 0 0 1 1 1 1 SWI2/SNF2 ATPase DEAD PF00270.29 KSA03630.1 - 0.00017 21.4 0.0 0.00059 19.7 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 KSA03630.1 - 0.0011 18.2 0.8 0.0011 18.2 0.8 2.0 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase Myb_DNA-binding PF00249.31 KSA03630.1 - 0.022 14.9 0.2 1.4 9.2 0.2 3.2 2 1 0 2 2 2 0 Myb-like DNA-binding domain AAA_14 PF13173.6 KSA03630.1 - 0.058 13.4 0.0 0.3 11.1 0.0 2.3 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.25 KSA03631.1 - 3.1e-64 216.9 0.0 4.6e-64 216.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KSA03631.1 - 1.7e-33 116.0 0.0 2.5e-33 115.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KSA03631.1 - 1.5e-13 50.7 0.0 2.4e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KSA03631.1 - 0.0012 18.2 0.0 0.0022 17.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 KSA03631.1 - 0.023 13.8 0.0 0.05 12.6 0.0 1.5 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 KSA03631.1 - 0.028 13.2 0.0 0.052 12.3 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 KSA03631.1 - 0.18 11.7 0.1 0.48 10.3 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family MHC_II_beta PF00969.19 KSA03632.1 - 0.14 12.3 0.0 0.3 11.2 0.0 1.5 1 0 0 1 1 1 0 Class II histocompatibility antigen, beta domain DUF3657 PF12394.8 KSA03633.1 - 0.012 16.1 0.1 0.04 14.5 0.1 1.9 1 0 0 1 1 1 0 Protein FAM135 PKD_channel PF08016.12 KSA03633.1 - 0.26 9.9 12.8 5.8 5.5 12.4 2.2 1 1 0 1 1 1 0 Polycystin cation channel NST1 PF13945.6 KSA03634.1 - 1.2e-15 58.1 11.9 1.3e-10 41.8 8.4 7.8 6 2 3 9 9 9 2 Salt tolerance down-regulator Patatin PF01734.22 KSA03634.1 - 0.077 13.2 0.0 0.27 11.4 0.0 1.9 1 0 0 1 1 1 0 Patatin-like phospholipase Ras PF00071.22 KSA03635.1 - 8.5e-48 162.0 0.0 9.8e-48 161.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KSA03635.1 - 1.9e-22 79.7 0.0 2.7e-22 79.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KSA03635.1 - 9e-07 28.5 0.0 1.3e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KSA03635.1 - 0.021 14.2 0.0 0.032 13.7 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KSA03635.1 - 0.12 12.4 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase EamA PF00892.20 KSA03636.1 - 9.1e-23 80.9 36.8 6e-13 49.1 10.0 2.1 2 0 0 2 2 2 2 EamA-like transporter family SLC35F PF06027.12 KSA03636.1 - 0.47 9.9 16.4 0.83 9.1 16.4 1.4 1 1 0 1 1 1 0 Solute carrier family 35 TPT PF03151.16 KSA03636.1 - 0.94 8.8 15.8 0.014 14.8 2.9 2.1 2 0 0 2 2 2 0 Triose-phosphate Transporter family Abhydrolase_1 PF00561.20 KSA03638.1 - 1.8e-11 44.2 0.1 5.7e-11 42.6 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KSA03638.1 - 5.1e-06 25.9 0.0 8.8e-06 25.2 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KSA03638.1 - 0.0037 17.9 0.0 0.0083 16.7 0.0 1.6 2 1 0 2 2 2 1 Alpha/beta hydrolase family Cutinase PF01083.22 KSA03638.1 - 0.028 14.4 0.0 0.042 13.8 0.0 1.2 1 0 0 1 1 1 0 Cutinase Abhydrolase_2 PF02230.16 KSA03638.1 - 0.077 12.8 0.0 0.3 10.8 0.0 1.9 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DUF676 PF05057.14 KSA03638.1 - 0.16 11.5 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) HEPN_RiboL-PSP PF18735.1 KSA03638.1 - 0.17 11.8 1.7 0.7 9.8 0.2 2.3 2 0 0 2 2 2 0 RiboL-PSP-HEPN Asp PF00026.23 KSA03639.1 - 4.3e-100 335.2 0.0 5.2e-100 334.9 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KSA03639.1 - 4.6e-15 56.3 0.3 1e-12 48.6 0.3 2.5 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KSA03639.1 - 8.3e-05 23.2 0.0 0.056 14.1 0.0 2.6 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.6 KSA03639.1 - 0.00018 21.3 0.0 0.001 18.9 0.0 2.1 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 KSA03639.1 - 0.00041 20.8 0.0 0.072 13.7 0.0 2.5 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease DUF1798 PF08807.10 KSA03640.1 - 0.017 15.2 0.1 0.063 13.4 0.1 1.9 1 0 0 1 1 1 0 Bacterial domain of unknown function (DUF1798) HSP70 PF00012.20 KSA03641.1 - 1.2e-264 879.1 13.7 1.4e-264 878.9 13.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KSA03641.1 - 3.5e-15 55.6 5.7 1.4e-13 50.3 2.9 2.4 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 KSA03641.1 - 0.0027 17.5 0.5 0.0081 15.9 0.0 2.1 3 0 0 3 3 3 1 FGGY family of carbohydrate kinases, C-terminal domain MRP-S27 PF10037.9 KSA03641.1 - 0.053 12.4 9.1 0.1 11.4 9.1 1.3 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 Ribosomal_L9_C PF03948.14 KSA03641.1 - 0.1 13.0 3.6 2.8 8.5 0.1 2.7 2 0 0 2 2 2 0 Ribosomal protein L9, C-terminal domain HXXSHH PF07586.11 KSA03641.1 - 0.66 9.5 4.5 1.2 8.7 4.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) FtsA PF14450.6 KSA03641.1 - 1.4 9.4 15.8 0.13 12.7 1.1 4.2 3 2 0 3 3 3 0 Cell division protein FtsA SMBP PF16785.5 KSA03641.1 - 1.7 8.9 6.4 1.4 9.2 4.3 1.9 2 0 0 2 2 2 0 Small metal-binding protein GCR1_C PF12550.8 KSA03642.1 - 7.8e-20 71.0 0.3 2e-19 69.7 0.3 1.7 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes IMUP PF15761.5 KSA03642.1 - 0.00094 19.9 4.1 0.00094 19.9 4.1 1.8 2 0 0 2 2 2 1 Immortalisation up-regulated protein Fib_alpha PF08702.10 KSA03642.1 - 5.8 7.1 9.3 0.28 11.4 0.3 2.9 2 1 1 4 4 4 0 Fibrinogen alpha/beta chain family Methyltransf_15 PF09445.10 KSA03643.1 - 6e-61 204.8 0.0 8.5e-61 204.3 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_25 PF13649.6 KSA03643.1 - 2.3e-05 25.0 0.0 0.00023 21.8 0.0 2.2 1 1 1 2 2 2 1 Methyltransferase domain MTS PF05175.14 KSA03643.1 - 0.0031 17.1 0.0 0.011 15.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_23 PF13489.6 KSA03643.1 - 0.015 15.2 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.16 KSA03643.1 - 0.015 15.0 0.0 0.021 14.5 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein N6_Mtase PF02384.16 KSA03643.1 - 0.039 13.2 0.0 0.064 12.5 0.0 1.3 1 0 0 1 1 1 0 N-6 DNA Methylase Methyltransf_31 PF13847.6 KSA03643.1 - 0.087 12.6 0.0 0.22 11.3 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 KSA03643.1 - 0.09 13.4 0.0 0.33 11.6 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Methyltr_RsmB-F PF01189.17 KSA03643.1 - 0.092 12.4 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Ubie_methyltran PF01209.18 KSA03643.1 - 0.1 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 KSA03643.1 - 0.15 11.5 0.0 0.28 10.6 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase MCM PF00493.23 KSA03644.1 - 8.8e-96 319.3 0.6 1.4e-95 318.7 0.6 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KSA03644.1 - 9e-32 109.6 0.0 1.7e-31 108.7 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KSA03644.1 - 4.4e-25 87.9 1.8 1.1e-24 86.7 1.8 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KSA03644.1 - 5.4e-15 55.8 0.1 2.1e-14 53.9 0.1 2.1 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KSA03644.1 - 1.9e-07 30.7 0.0 2.6e-06 27.0 0.0 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KSA03644.1 - 0.0026 17.6 0.0 0.0054 16.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KSA03644.1 - 0.0046 16.7 0.0 0.017 14.9 0.0 1.9 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 KSA03644.1 - 0.045 13.7 0.0 0.22 11.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NOA36 PF06524.12 KSA03644.1 - 0.34 10.2 2.2 0.61 9.4 2.2 1.3 1 0 0 1 1 1 0 NOA36 protein DUF2052 PF09747.9 KSA03644.1 - 4.9 7.2 21.5 2 8.5 18.7 1.7 1 1 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) PBP1_TM PF14812.6 KSA03644.1 - 7.5 7.0 7.9 20 5.6 7.9 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CBF PF03914.17 KSA03645.1 - 7.5e-31 107.4 1.1 7.5e-31 107.4 1.1 2.4 3 0 0 3 3 3 1 CBF/Mak21 family BBP1_C PF15272.6 KSA03645.1 - 0.0087 15.9 6.2 0.02 14.7 6.2 1.7 1 0 0 1 1 1 1 Spindle pole body component BBP1, C-terminal DUF3347 PF11827.8 KSA03645.1 - 0.11 12.6 4.4 0.2 11.8 4.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) DUF3510 PF12022.8 KSA03645.1 - 3.2 8.1 6.4 0.68 10.3 1.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3510) Ribosomal_L21e PF01157.18 KSA03646.1 - 9.9e-48 160.2 5.6 1.3e-47 159.8 3.3 1.9 2 0 0 2 2 2 1 Ribosomal protein L21e HIRAN PF08797.11 KSA03646.1 - 0.017 15.1 0.4 0.052 13.5 0.2 1.9 2 1 0 2 2 2 0 HIRAN domain Surface_Ag_2 PF01617.17 KSA03646.1 - 0.04 13.3 0.2 0.048 13.1 0.2 1.2 1 0 0 1 1 1 0 Surface antigen AA_permease PF00324.21 KSA03647.1 - 2.1e-95 320.1 45.4 2.4e-95 319.9 45.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KSA03647.1 - 6.2e-31 107.7 52.5 7.6e-31 107.4 52.5 1.0 1 0 0 1 1 1 1 Amino acid permease CwfJ_C_1 PF04677.15 KSA03648.1 - 1.2e-27 96.2 0.1 2.4e-27 95.2 0.1 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 KSA03648.1 - 6.8e-16 59.0 0.9 1.5e-15 57.9 0.9 1.6 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 SET PF00856.28 KSA03649.1 - 4.5e-16 59.7 0.0 1.1e-15 58.4 0.0 1.6 1 1 0 1 1 1 1 SET domain YHS PF04945.13 KSA03649.1 - 0.007 16.4 0.1 0.007 16.4 0.1 2.3 2 0 0 2 2 2 1 YHS domain KNOX1 PF03790.13 KSA03649.1 - 0.27 11.0 1.6 1.3 8.8 0.0 2.5 3 0 0 3 3 3 0 KNOX1 domain AA_permease PF00324.21 KSA03650.1 - 7.7e-126 420.5 38.1 9.6e-126 420.2 38.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KSA03650.1 - 8.9e-37 126.9 35.7 1.1e-36 126.7 35.7 1.0 1 0 0 1 1 1 1 Amino acid permease Gpr1_Fun34_YaaH PF01184.19 KSA03651.1 - 3.1e-89 298.1 20.8 3.6e-89 297.8 20.8 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family S_4TM PF18159.1 KSA03651.1 - 0.0071 15.7 0.7 0.012 15.0 0.7 1.3 1 0 0 1 1 1 1 SMODS-associating 4TM effector domain Pkinase PF00069.25 KSA03652.1 - 3.5e-56 190.5 0.0 1.9e-55 188.1 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KSA03652.1 - 3.2e-26 92.2 0.0 1.3e-18 67.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.24 KSA03652.1 - 9.9e-06 26.2 3.2 2.5e-05 24.9 3.2 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 KSA03652.1 - 0.00021 20.3 1.4 0.00073 18.6 1.4 2.1 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KSA03652.1 - 0.00086 18.7 0.0 0.029 13.7 0.0 2.6 3 0 0 3 3 3 1 Kinase-like Kdo PF06293.14 KSA03652.1 - 0.0029 17.0 0.0 0.0059 16.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KSA03652.1 - 0.039 13.9 0.1 0.16 11.8 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family RNase_PH PF01138.21 KSA03653.1 - 2.2e-17 63.8 0.1 3.9e-17 63.0 0.1 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Nop PF01798.18 KSA03654.1 - 9.8e-57 192.1 1.7 9.8e-57 192.1 1.7 2.0 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 KSA03654.1 - 8.3e-31 107.4 3.9 1.5e-30 106.5 3.9 1.5 1 0 0 1 1 1 1 Prp31 C terminal domain GIY-YIG PF01541.24 KSA03654.1 - 0.021 15.1 2.1 4.7 7.6 0.2 2.7 2 0 0 2 2 2 0 GIY-YIG catalytic domain tRNA-synt_1 PF00133.22 KSA03655.1 - 2.7e-228 759.1 0.9 3.7e-227 755.4 0.9 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KSA03655.1 - 1e-36 126.2 0.3 3.1e-36 124.6 0.3 1.9 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KSA03655.1 - 3.1e-14 52.6 0.6 1.8e-07 30.2 0.1 4.6 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 KSA03655.1 - 2.1e-09 37.1 0.0 7.7e-07 28.8 0.0 3.5 3 1 1 4 4 4 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 KSA03655.1 - 0.082 12.2 3.7 1.5 8.1 0.0 3.4 4 0 0 4 4 4 0 tRNA synthetases class I (C) catalytic domain tRNA-synt_1b PF00579.25 KSA03655.1 - 0.5 9.6 0.0 0.5 9.6 0.0 2.9 4 0 0 4 4 4 0 tRNA synthetases class I (W and Y) tRNA-synt_1c PF00749.21 KSA03655.1 - 6.9 5.5 11.2 0.87 8.4 0.1 3.2 3 0 0 3 3 3 0 tRNA synthetases class I (E and Q), catalytic domain HLH PF00010.26 KSA03657.1 - 8.9e-11 41.6 0.3 1.7e-10 40.7 0.3 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Peptidase_M41 PF01434.18 KSA03658.1 - 2.2e-60 203.8 0.0 4.1e-60 202.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 KSA03658.1 - 2.4e-41 141.3 0.0 3.1e-40 137.6 0.0 2.6 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KSA03658.1 - 8e-07 28.8 0.0 1.8e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KSA03658.1 - 1.7e-05 25.3 0.4 0.00058 20.3 0.3 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KSA03658.1 - 2.5e-05 24.6 0.1 0.12 12.7 0.0 3.5 4 0 0 4 4 4 2 AAA domain TIP49 PF06068.13 KSA03658.1 - 5.3e-05 22.6 0.0 0.00012 21.5 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain RuvB_N PF05496.12 KSA03658.1 - 0.00043 20.0 0.0 0.014 15.1 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KSA03658.1 - 0.0011 18.9 0.1 0.0055 16.7 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KSA03658.1 - 0.0045 17.1 0.0 0.23 11.6 0.0 3.1 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 KSA03658.1 - 0.031 14.0 0.0 0.056 13.2 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 KSA03658.1 - 0.054 12.9 0.2 0.11 11.9 0.2 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 KSA03658.1 - 0.081 12.5 0.7 1.2 8.6 0.6 2.3 1 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KSA03658.1 - 0.088 13.0 0.0 0.21 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KSA03658.1 - 0.12 11.9 0.1 0.81 9.2 0.1 2.1 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 KSA03658.1 - 0.12 12.9 0.3 0.35 11.4 0.1 1.9 2 0 0 2 2 1 0 AAA domain Cnd2 PF05786.14 KSA03659.1 - 5.7e-158 527.9 25.8 1.4e-157 526.6 25.8 1.5 1 1 0 1 1 1 1 Condensin complex subunit 2 CNDH2_N PF06278.11 KSA03659.1 - 0.037 14.3 1.3 0.085 13.1 0.0 2.3 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal DUF4602 PF15375.6 KSA03660.1 - 0.072 13.4 16.8 0.62 10.4 1.0 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4602) His_biosynth PF00977.21 KSA03661.1 - 4.6e-24 85.2 0.1 6.3e-24 84.7 0.1 1.1 1 0 0 1 1 1 1 Histidine biosynthesis protein GON PF08685.11 KSA03661.1 - 0.043 13.7 0.0 0.058 13.2 0.0 1.3 1 0 0 1 1 1 0 GON domain BtpA PF03437.15 KSA03661.1 - 0.058 12.8 0.1 0.2 11.1 0.0 1.8 2 0 0 2 2 2 0 BtpA family RNA_pol_A_bac PF01000.26 KSA03662.1 - 8e-31 106.7 0.0 1.3e-30 106.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 KSA03662.1 - 1.9e-16 59.2 0.0 2.5e-16 58.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF1770 PF08589.10 KSA03663.1 - 0.025 15.5 0.2 0.059 14.3 0.1 1.6 1 1 1 2 2 2 0 Fungal protein of unknown function (DUF1770) RabGAP-TBC PF00566.18 KSA03665.1 - 1e-50 172.4 1.5 3.2e-50 170.8 1.5 1.9 1 0 0 1 1 1 1 Rab-GTPase-TBC domain GRAM PF02893.20 KSA03665.1 - 1e-09 38.2 0.0 4.7e-09 36.1 0.0 2.2 1 0 0 1 1 1 1 GRAM domain Vps36_ESCRT-II PF11605.8 KSA03665.1 - 0.00076 19.6 0.0 0.0019 18.3 0.0 1.7 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 PAM2 PF07145.15 KSA03665.1 - 0.89 9.4 4.3 0.69 9.7 2.1 2.0 2 0 0 2 2 2 0 Ataxin-2 C-terminal region ANAPC8 PF04049.13 KSA03665.1 - 0.99 9.4 3.8 0.56 10.3 0.1 2.4 3 0 0 3 3 3 0 Anaphase promoting complex subunit 8 / Cdc23 Fmp27 PF10344.9 KSA03666.1 - 3.6e-153 511.8 48.6 3.6e-153 511.8 48.6 2.7 3 0 0 3 3 3 1 Mitochondrial protein from FMP27 Fmp27_WPPW PF10359.9 KSA03666.1 - 6.3e-137 457.3 13.5 6.3e-137 457.3 13.5 2.0 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Apt1 PF10351.9 KSA03666.1 - 1.8e-114 383.2 16.7 1.8e-114 383.2 16.7 2.8 2 1 0 2 2 2 1 Golgi-body localisation protein domain Fmp27_GFWDK PF10347.9 KSA03666.1 - 2.9e-54 183.4 0.1 1.3e-53 181.3 0.0 2.3 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 KSA03666.1 - 8.5e-44 149.2 2.5 8.5e-44 149.2 2.5 3.0 2 1 0 2 2 2 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.9 KSA03666.1 - 7.3e-21 74.8 4.5 7.9e-21 74.7 0.2 3.6 3 0 0 3 3 3 1 RNA pol II promoter Fmp27 protein domain F_actin_bind PF08919.10 KSA03668.1 - 0.093 12.8 0.1 0.14 12.3 0.1 1.3 1 0 0 1 1 1 0 F-actin binding WHIM1 PF15612.6 KSA03671.1 - 0.03 13.9 0.2 0.065 12.8 0.2 1.5 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 Leu_Phe_trans PF03588.14 KSA03671.1 - 0.18 11.3 0.0 0.57 9.7 0.0 1.8 2 0 0 2 2 2 0 Leucyl/phenylalanyl-tRNA protein transferase SWIB PF02201.18 KSA03672.1 - 6.4e-10 38.8 2.2 7.5e-06 25.8 0.1 2.9 3 0 0 3 3 3 2 SWIB/MDM2 domain DUF4635 PF15466.6 KSA03672.1 - 0.034 13.7 0.1 0.071 12.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4635) Cyt-b5 PF00173.28 KSA03673.1 - 1.1e-13 51.1 0.0 2.1e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.24 KSA03673.1 - 9.1e-11 42.1 2.4 9.1e-11 42.1 2.4 1.6 2 0 0 2 2 2 1 Fatty acid desaturase OST3_OST6 PF04756.13 KSA03673.1 - 0.008 15.6 0.1 0.029 13.7 0.0 1.9 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family CBS PF00571.28 KSA03674.1 - 3.8e-14 52.9 0.0 1.1e-07 32.2 0.0 2.2 2 0 0 2 2 2 2 CBS domain Hormone_3 PF00159.18 KSA03674.1 - 0.11 12.6 0.0 13 5.9 0.0 2.8 2 0 0 2 2 2 0 Pancreatic hormone peptide ADH_zinc_N PF00107.26 KSA03675.1 - 2.9e-24 85.5 0.0 4.8e-24 84.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KSA03675.1 - 1e-15 59.0 0.0 2e-15 58.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KSA03675.1 - 2e-10 40.5 0.0 3.7e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 KSA03675.1 - 0.0045 16.5 0.1 0.0063 16.0 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase TrkA_N PF02254.18 KSA03675.1 - 0.011 16.0 0.2 0.024 14.9 0.2 1.5 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_10 PF13460.6 KSA03675.1 - 0.029 14.3 0.3 0.044 13.7 0.3 1.3 1 0 0 1 1 1 0 NAD(P)H-binding Methyltransf_15 PF09445.10 KSA03675.1 - 0.048 13.2 0.1 0.092 12.3 0.1 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase RRM_1 PF00076.22 KSA03676.1 - 1.7e-33 114.2 0.0 2e-16 59.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KSA03676.1 - 0.00016 21.7 0.0 0.0039 17.3 0.0 2.6 2 2 0 2 2 2 1 RNA recognition motif RRM_5 PF13893.6 KSA03676.1 - 0.00046 19.8 0.1 0.14 11.7 0.0 2.3 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.11 KSA03676.1 - 0.037 13.7 0.3 2 8.2 0.0 3.0 3 0 0 3 3 3 0 Ribonuclease B OB domain PHM7_cyt PF14703.6 KSA03676.1 - 0.043 14.0 0.0 2.2 8.5 0.0 2.3 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter CSD PF00313.22 KSA03676.1 - 0.31 10.9 1.3 25 4.8 0.2 2.7 3 0 0 3 3 3 0 'Cold-shock' DNA-binding domain CDC45 PF02724.14 KSA03677.1 - 0.0041 15.5 3.3 0.005 15.2 3.3 1.2 1 0 0 1 1 1 1 CDC45-like protein Nop14 PF04147.12 KSA03677.1 - 0.1 10.8 5.7 0.12 10.6 5.7 1.1 1 0 0 1 1 1 0 Nop14-like family AF-4 PF05110.13 KSA03677.1 - 0.24 9.4 20.2 0.3 9.1 20.2 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Ribosomal_L9_N PF01281.19 KSA03678.1 - 1.4e-08 34.2 0.0 3.1e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain Gemini_AL2 PF01440.16 KSA03678.1 - 0.014 15.8 0.1 0.025 15.0 0.1 1.4 1 0 0 1 1 1 0 Geminivirus AL2 protein Lin-8 PF03353.15 KSA03678.1 - 0.022 14.4 1.8 0.027 14.0 1.8 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SPT2 PF08243.11 KSA03678.1 - 0.058 13.9 2.1 0.09 13.3 2.1 1.2 1 0 0 1 1 1 0 SPT2 chromatin protein Spore_III_AB PF09548.10 KSA03678.1 - 0.063 13.4 0.2 0.11 12.6 0.1 1.4 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) PA26 PF04636.13 KSA03678.1 - 0.44 9.4 3.6 0.6 9.0 3.6 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Stk19 PF10494.9 KSA03679.1 - 2.5e-75 253.3 0.0 4.5e-75 252.5 0.0 1.4 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 DUF1682 PF07946.14 KSA03680.1 - 3.3e-89 299.3 9.7 3.8e-89 299.1 9.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Ank_5 PF13857.6 KSA03681.1 - 6.1e-14 51.9 0.0 2.2e-11 43.8 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KSA03681.1 - 1.1e-12 48.2 0.2 3.1e-06 27.6 0.1 2.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KSA03681.1 - 5.1e-08 33.4 0.0 8.8e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KSA03681.1 - 7.1e-07 29.4 0.1 3.6e-06 27.2 0.2 2.2 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 KSA03681.1 - 2.9e-06 27.2 0.2 3e-05 24.1 0.1 2.6 3 0 0 3 3 3 1 Ankyrin repeat GGA_N-GAT PF18308.1 KSA03681.1 - 0.036 13.7 0.8 0.35 10.5 0.3 2.7 2 0 0 2 2 2 0 GGA N-GAT domain Peptidase_M76 PF09768.9 KSA03682.1 - 2.4e-68 229.2 0.3 3e-68 228.9 0.3 1.1 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.9 KSA03682.1 - 0.0083 16.0 0.1 0.013 15.3 0.1 1.5 1 1 0 1 1 1 1 SprT-like family Peptidase_M91 PF14891.6 KSA03682.1 - 0.13 12.6 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 Effector protein MBOAT PF03062.19 KSA03683.1 - 2.2e-50 172.0 30.7 8.1e-50 170.1 30.7 1.8 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 KSA03683.1 - 0.085 13.1 4.6 0.055 13.8 1.6 2.1 2 0 0 2 2 2 0 Membrane bound O-acyl transferase family Presenilin PF01080.17 KSA03683.1 - 7.5 5.2 10.5 0.076 11.8 0.2 2.2 2 0 0 2 2 2 0 Presenilin MBOAT PF03062.19 KSA03684.1 - 1.1e-48 166.4 24.9 1.5e-47 162.6 24.9 2.5 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 KSA03684.1 - 0.00092 19.4 2.3 0.00092 19.4 2.3 2.2 3 0 0 3 3 3 1 Membrane bound O-acyl transferase family WBS_methylT PF12589.8 KSA03685.1 - 7.4e-13 49.1 6.4 1.3e-12 48.3 6.4 1.4 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 KSA03685.1 - 2.6e-11 44.0 0.0 5.3e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KSA03685.1 - 2.1e-10 41.2 0.0 6.2e-10 39.7 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KSA03685.1 - 1e-06 29.4 0.1 5e-06 27.2 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KSA03685.1 - 7.3e-05 22.7 0.0 0.00011 22.1 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain AdoMet_MTase PF07757.13 KSA03685.1 - 0.00095 19.5 0.0 0.0021 18.3 0.0 1.6 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_31 PF13847.6 KSA03685.1 - 0.006 16.4 0.0 0.013 15.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 KSA03685.1 - 0.014 15.0 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW PrmA PF06325.13 KSA03685.1 - 0.036 13.5 0.1 0.11 11.8 0.0 1.7 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Bin3 PF06859.12 KSA03685.1 - 0.079 13.6 0.3 1.4 9.6 0.0 2.4 1 1 1 2 2 2 0 Bicoid-interacting protein 3 (Bin3) Methyltransf_32 PF13679.6 KSA03685.1 - 0.092 12.7 0.2 2.4 8.2 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Ribosomal_L19 PF01245.20 KSA03686.1 - 1.4e-07 31.4 1.5 3e-07 30.4 1.5 1.5 1 1 0 1 1 1 1 Ribosomal protein L19 DUF727 PF05303.12 KSA03687.1 - 5e-08 33.0 0.3 1.4e-07 31.5 0.3 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF727) DUF3237 PF11578.8 KSA03687.1 - 0.05 13.4 0.0 0.058 13.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3237) Ribosomal_S3Ae PF01015.18 KSA03687.1 - 0.058 13.0 0.1 0.063 12.9 0.1 1.3 1 1 0 1 1 1 0 Ribosomal S3Ae family LSM PF01423.22 KSA03688.1 - 9.7e-09 34.8 0.1 1.2e-08 34.5 0.1 1.1 1 0 0 1 1 1 1 LSM domain zf-C2H2 PF00096.26 KSA03690.1 - 1.5e-14 53.5 23.3 9.4e-05 22.7 2.7 4.9 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KSA03690.1 - 4e-14 52.1 20.0 0.00033 21.2 0.7 5.1 5 0 0 5 5 5 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KSA03690.1 - 1.1e-10 41.4 23.1 0.0013 19.0 0.2 4.9 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KSA03690.1 - 0.00011 22.4 6.8 0.00072 19.8 0.0 3.9 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KSA03690.1 - 0.004 17.5 0.6 0.004 17.5 0.6 3.7 4 0 0 4 4 4 1 Zinc-finger of C2H2 type GAGA PF09237.11 KSA03690.1 - 0.014 15.2 0.8 0.03 14.1 0.2 1.8 2 0 0 2 2 2 0 GAGA factor zf-TRAF PF02176.18 KSA03690.1 - 2.4 8.9 11.0 2.6 8.8 0.0 3.2 1 1 2 3 3 3 0 TRAF-type zinc finger zf_ZIC PF18366.1 KSA03690.1 - 8.9 6.5 10.8 7.2 6.8 0.1 3.8 3 1 1 4 4 4 0 Zic proteins zinc finger domain zf-C2H2_aberr PF17017.5 KSA03690.1 - 9.1 6.4 14.0 1 9.5 0.2 3.6 2 1 2 4 4 4 0 Aberrant zinc-finger Abhydrolase_1 PF00561.20 KSA03691.1 - 6.5e-31 107.9 0.1 7.9e-31 107.6 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KSA03691.1 - 1.6e-12 48.5 0.0 2e-12 48.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KSA03691.1 - 6.5e-06 25.6 0.0 0.00043 19.6 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Ndr PF03096.14 KSA03691.1 - 0.00092 18.0 0.0 0.0012 17.6 0.0 1.1 1 0 0 1 1 1 1 Ndr family FSH1 PF03959.13 KSA03691.1 - 0.01 15.5 0.0 2.5 7.7 0.0 2.3 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 KSA03691.1 - 0.011 15.5 0.0 9.6 5.9 0.0 2.9 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase EHN PF06441.12 KSA03691.1 - 0.018 15.4 0.0 3.5 8.1 0.0 2.5 2 0 0 2 2 2 0 Epoxide hydrolase N terminus ABC_tran PF00005.27 KSA03692.1 - 1.4e-46 158.4 0.0 5.7e-24 85.2 0.0 4.1 2 2 0 2 2 2 2 ABC transporter 4HB PF17947.1 KSA03692.1 - 1.4e-28 98.7 0.0 7.6e-28 96.4 0.0 2.4 2 0 0 2 2 1 1 Four helical bundle domain AAA_21 PF13304.6 KSA03692.1 - 1.3e-16 61.3 2.1 0.0056 16.5 0.0 4.4 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KSA03692.1 - 3.1e-15 56.2 0.4 4.5e-05 23.0 0.0 4.1 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KSA03692.1 - 1.9e-09 38.4 10.3 0.00062 20.3 0.1 4.0 5 0 0 5 5 3 2 AAA domain RsgA_GTPase PF03193.16 KSA03692.1 - 4.5e-09 36.4 0.0 0.00065 19.6 0.0 2.8 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 KSA03692.1 - 1.1e-08 34.7 0.0 0.0069 16.1 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_28 PF13521.6 KSA03692.1 - 1.4e-07 31.9 0.0 0.0021 18.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 KSA03692.1 - 1.9e-07 31.1 0.0 0.003 17.6 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 KSA03692.1 - 5.3e-07 30.0 0.0 0.027 14.7 0.0 3.9 4 0 0 4 4 3 2 AAA domain RNA_helicase PF00910.22 KSA03692.1 - 1.5e-05 25.3 0.0 0.19 12.2 0.0 3.1 2 0 0 2 2 2 2 RNA helicase Dynamin_N PF00350.23 KSA03692.1 - 2e-05 24.7 0.0 0.0009 19.3 0.0 3.0 2 0 0 2 2 2 1 Dynamin family AAA_18 PF13238.6 KSA03692.1 - 2.6e-05 24.8 0.0 0.38 11.3 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 KSA03692.1 - 6.3e-05 22.9 2.0 0.22 11.2 0.0 3.7 4 0 0 4 4 4 2 AAA ATPase domain MeaB PF03308.16 KSA03692.1 - 8.1e-05 21.7 0.0 0.22 10.5 0.0 2.4 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 KSA03692.1 - 8.2e-05 23.0 0.2 0.16 12.4 0.0 3.4 4 0 0 4 4 3 1 AAA ATPase domain AAA_33 PF13671.6 KSA03692.1 - 8.3e-05 22.8 0.0 0.58 10.3 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 KSA03692.1 - 0.00014 22.3 0.3 0.56 10.6 0.0 4.1 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) AAA_27 PF13514.6 KSA03692.1 - 0.00021 21.0 0.0 0.22 11.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KSA03692.1 - 0.00052 19.8 0.0 1.4 8.6 0.0 3.4 3 1 0 3 3 3 1 AAA domain PduV-EutP PF10662.9 KSA03692.1 - 0.0006 19.6 0.0 0.12 12.1 0.0 3.4 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation HEAT_2 PF13646.6 KSA03692.1 - 0.00068 20.0 4.2 0.017 15.5 1.6 3.1 2 1 2 4 4 3 3 HEAT repeats AAA_24 PF13479.6 KSA03692.1 - 0.0019 18.0 0.0 1.3 8.7 0.0 2.9 3 0 0 3 3 2 1 AAA domain SbcCD_C PF13558.6 KSA03692.1 - 0.0023 18.1 0.0 0.75 10.1 0.0 3.2 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit ATPase_2 PF01637.18 KSA03692.1 - 0.0032 17.4 0.1 5.5 6.8 0.0 3.6 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea DUF87 PF01935.17 KSA03692.1 - 0.0052 16.9 7.2 0.38 10.8 0.0 4.3 5 0 0 5 5 3 1 Helicase HerA, central domain NACHT PF05729.12 KSA03692.1 - 0.006 16.5 0.0 2.1 8.2 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_14 PF13173.6 KSA03692.1 - 0.0063 16.5 0.0 6.3 6.8 0.0 3.2 3 0 0 3 3 2 0 AAA domain CLP1_P PF16575.5 KSA03692.1 - 0.0064 16.3 0.0 1.5 8.6 0.0 3.2 3 0 0 3 3 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop cobW PF02492.19 KSA03692.1 - 0.0079 15.8 0.1 5.7 6.5 0.0 3.2 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain Vac14_Fab1_bd PF12755.7 KSA03692.1 - 0.008 16.8 0.1 1.2 9.8 0.0 2.9 2 1 1 3 3 2 1 Vacuolar 14 Fab1-binding region Rad17 PF03215.15 KSA03692.1 - 0.008 16.1 0.0 4.4 7.2 0.0 2.7 2 0 0 2 2 2 0 Rad17 P-loop domain IstB_IS21 PF01695.17 KSA03692.1 - 0.0096 15.7 0.1 3.8 7.2 0.0 3.1 3 0 0 3 3 2 0 IstB-like ATP binding protein Roc PF08477.13 KSA03692.1 - 0.013 15.7 0.0 8.8 6.6 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase UME PF08064.13 KSA03692.1 - 0.022 14.6 0.8 0.091 12.7 0.5 2.2 1 1 0 2 2 1 0 UME (NUC010) domain Ploopntkinase3 PF18751.1 KSA03692.1 - 0.028 14.3 0.0 5.4 6.9 0.0 2.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 Cytidylate_kin PF02224.18 KSA03692.1 - 0.034 13.9 0.0 9.7 5.9 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase AAA_7 PF12775.7 KSA03692.1 - 0.034 13.6 0.0 7.6 6.0 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region CLASP_N PF12348.8 KSA03692.1 - 0.035 13.7 1.6 1.4 8.4 0.4 2.8 2 1 1 3 3 3 0 CLASP N terminal ParcG PF10274.9 KSA03692.1 - 0.04 14.0 0.5 5.3 7.1 0.1 2.7 2 1 0 2 2 2 0 Parkin co-regulated protein Septin PF00735.18 KSA03692.1 - 0.043 13.1 0.6 3.2 7.0 0.0 3.0 3 0 0 3 3 3 0 Septin Mg_chelatase PF01078.21 KSA03692.1 - 0.062 12.7 0.1 2.6 7.4 0.0 3.0 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI TsaE PF02367.17 KSA03692.1 - 0.065 13.2 0.0 6.2 6.8 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 KSA03692.1 - 0.068 12.4 2.3 9.2 5.5 0.0 3.8 5 0 0 5 5 4 0 Zeta toxin NTPase_1 PF03266.15 KSA03692.1 - 0.081 12.8 0.1 16 5.3 0.0 2.7 2 0 0 2 2 2 0 NTPase G-alpha PF00503.20 KSA03692.1 - 0.085 12.0 0.0 14 4.7 0.0 2.6 3 0 0 3 3 3 0 G-protein alpha subunit MukB PF04310.12 KSA03692.1 - 0.1 12.4 0.1 11 5.8 0.0 2.5 2 0 0 2 2 2 0 MukB N-terminal ATP_bind_1 PF03029.17 KSA03692.1 - 0.11 12.2 2.0 7.4 6.3 0.0 3.0 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein MutS_V PF00488.21 KSA03692.1 - 0.12 12.4 0.1 6.4 6.7 0.1 2.5 2 0 0 2 2 2 0 MutS domain V Adeno_IVa2 PF02456.15 KSA03692.1 - 0.15 10.9 0.1 6.5 5.4 0.0 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_17 PF13207.6 KSA03692.1 - 1.4 9.4 4.4 71 3.8 0.4 4.2 3 1 0 3 3 2 0 AAA domain D5_N PF08706.11 KSA03692.1 - 3.6 7.8 5.8 2.6 8.3 1.5 2.8 3 0 0 3 3 2 0 D5 N terminal like AAA_13 PF13166.6 KSA03692.1 - 5.5 5.5 13.6 0.84 8.2 0.0 4.0 5 0 0 5 5 5 0 AAA domain DUF3437 PF11919.8 KSA03692.1 - 8 6.5 5.7 26 4.8 0.1 4.2 3 1 3 6 6 4 0 Domain of unknown function (DUF3437) HEAT_EZ PF13513.6 KSA03692.1 - 8.2 7.1 7.4 71 4.1 0.0 4.3 3 1 2 5 5 3 0 HEAT-like repeat PLA2_B PF01735.18 KSA03693.1 - 3.9e-108 362.0 13.8 2.2e-62 211.1 0.2 3.5 3 1 0 3 3 3 3 Lysophospholipase catalytic domain TSA PF03249.13 KSA03693.1 - 0.11 11.2 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 Type specific antigen Ammonium_transp PF00909.21 KSA03694.1 - 9.6e-71 238.6 16.8 3.3e-40 138.0 10.7 2.0 2 0 0 2 2 2 2 Ammonium Transporter Family Tetraspanin PF00335.20 KSA03694.1 - 0.0066 16.2 0.2 0.0066 16.2 0.2 2.9 3 1 0 3 3 3 1 Tetraspanin family Mito_carr PF00153.27 KSA03695.1 - 1.9e-60 200.8 2.6 1.4e-19 69.8 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein SOG2 PF10428.9 KSA03696.1 - 7e-61 207.0 27.2 8.9e-34 117.6 9.8 5.4 2 1 2 4 4 4 2 RAM signalling pathway protein DUF1053 PF06327.14 KSA03696.1 - 0.07 13.7 2.4 0.33 11.5 0.1 3.0 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1053) Glutaredoxin2_C PF04399.13 KSA03696.1 - 0.1 12.5 0.4 0.73 9.7 0.1 2.4 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain HMA PF00403.26 KSA03697.1 - 2.3e-13 50.4 0.1 4.3e-13 49.5 0.1 1.4 1 0 0 1 1 1 1 Heavy-metal-associated domain Sod_Cu PF00080.20 KSA03697.1 - 0.0001 22.5 0.0 0.00016 21.8 0.0 1.3 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) DUF3419 PF11899.8 KSA03698.1 - 8.6e-156 518.9 0.0 1.3e-155 518.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.6 KSA03698.1 - 8.7e-11 41.9 0.0 4e-10 39.8 0.0 2.1 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 KSA03698.1 - 1.4e-10 41.8 0.0 6.3e-10 39.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KSA03698.1 - 7.3e-10 39.4 0.1 8.2e-09 36.1 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KSA03698.1 - 2.4e-09 37.7 0.0 6.6e-09 36.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KSA03698.1 - 3.9e-09 36.2 0.1 8.4e-09 35.1 0.1 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KSA03698.1 - 4.4e-07 29.8 0.0 1.7e-06 27.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 KSA03698.1 - 0.0082 15.9 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_28 PF02636.17 KSA03698.1 - 0.014 15.0 0.0 0.048 13.3 0.0 1.8 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase AAA_16 PF13191.6 KSA03698.1 - 0.034 14.5 0.0 0.066 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Rsm22 PF09243.10 KSA03698.1 - 0.11 11.7 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 CM_2 PF01817.21 KSA03699.1 - 0.0097 16.2 0.0 0.75 10.2 0.0 2.8 2 1 0 2 2 2 2 Chorismate mutase type II DnaJ PF00226.31 KSA03700.1 - 7.1e-07 29.3 0.9 2e-06 27.8 0.9 1.9 1 0 0 1 1 1 1 DnaJ domain Myco_arth_vir_N PF09610.10 KSA03700.1 - 0.036 14.2 0.0 0.073 13.2 0.0 1.5 1 0 0 1 1 1 0 Mycoplasma virulence signal region (Myco_arth_vir_N) HCMV_UL139 PF12507.8 KSA03700.1 - 0.087 13.2 3.8 3.4 8.1 0.1 3.5 2 1 1 3 3 3 0 Human Cytomegalovirus UL139 protein LHH PF14411.6 KSA03700.1 - 1.3 9.2 5.8 0.33 11.1 0.2 2.4 2 0 0 2 2 2 0 A nuclease of the HNH/ENDO VII superfamily with conserved LHH Amidohydro_1 PF01979.20 KSA03701.1 - 8.4e-17 61.5 0.1 1.6e-16 60.6 0.1 1.4 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KSA03701.1 - 1.7e-14 54.2 0.1 7.5e-10 38.9 0.0 3.2 4 0 0 4 4 4 2 Amidohydrolase family Glucosamine_iso PF01182.20 KSA03702.1 - 5.6e-17 62.4 0.0 1.2e-16 61.4 0.0 1.5 1 1 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Hexokinase_2 PF03727.16 KSA03703.1 - 9.4e-49 166.0 0.0 1.7e-48 165.1 0.0 1.4 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KSA03703.1 - 9.7e-31 107.2 0.0 1.4e-30 106.7 0.0 1.2 1 0 0 1 1 1 1 Hexokinase E3_UFM1_ligase PF09743.9 KSA03703.1 - 0.046 13.3 0.3 0.41 10.2 0.1 2.3 2 0 0 2 2 2 0 E3 UFM1-protein ligase 1 RHD3 PF05879.12 KSA03704.1 - 2.4e-258 859.2 11.8 2.9e-258 858.9 11.8 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.19 KSA03704.1 - 5.5e-09 35.7 0.5 1.1e-08 34.7 0.5 1.5 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.23 KSA03704.1 - 5.2e-05 23.3 0.1 0.00017 21.7 0.1 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KSA03704.1 - 0.00017 21.7 1.4 0.00046 20.3 0.0 2.5 2 0 0 2 2 2 1 Dynamin family AAA_28 PF13521.6 KSA03704.1 - 0.0007 19.9 0.0 0.0015 18.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain Roc PF08477.13 KSA03704.1 - 0.05 13.8 0.1 0.14 12.4 0.1 1.8 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase DUF5446 PF17522.2 KSA03704.1 - 0.1 12.8 1.0 7.7 6.8 0.0 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5446) GTP_EFTU PF00009.27 KSA03705.1 - 4.6e-62 209.0 0.1 8.1e-62 208.2 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 KSA03705.1 - 1.6e-22 79.3 0.0 3.9e-22 78.1 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 KSA03705.1 - 8.5e-16 57.8 0.0 6e-09 35.8 0.0 2.8 2 0 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KSA03705.1 - 1.1e-13 51.3 0.6 3.7e-13 49.7 0.3 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KSA03705.1 - 0.00073 19.6 0.1 0.0017 18.4 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RF3_C PF16658.5 KSA03705.1 - 0.0073 16.1 0.0 0.02 14.7 0.0 1.7 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MFS_1 PF07690.16 KSA03706.1 - 3.4e-17 62.4 44.8 3.4e-17 62.4 44.8 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 KSA03706.1 - 9e-10 37.7 41.0 9.1e-07 27.8 8.0 2.3 1 1 1 2 2 2 2 MFS/sugar transport protein LRR_8 PF13855.6 KSA03707.1 - 2.5e-23 81.6 20.7 4.7e-07 29.5 0.0 6.7 5 1 2 7 7 7 6 Leucine rich repeat LRR_4 PF12799.7 KSA03707.1 - 6.4e-22 77.3 37.6 1.9e-05 24.9 0.2 9.1 5 2 5 10 10 10 8 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KSA03707.1 - 9.8e-10 37.7 5.7 0.89 9.8 0.3 8.8 9 0 0 9 9 9 2 Leucine Rich repeat FNIP PF05725.12 KSA03707.1 - 2.7e-09 37.0 34.8 0.00016 21.8 4.7 7.2 5 2 3 8 8 8 3 FNIP Repeat LRR_5 PF13306.6 KSA03707.1 - 2.6e-08 33.9 2.3 0.036 14.0 0.1 4.5 2 1 2 4 4 4 4 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 KSA03707.1 - 0.00015 21.9 22.2 5.2 8.0 0.0 9.8 9 2 0 9 9 9 2 Leucine Rich Repeat LRR_9 PF14580.6 KSA03707.1 - 1.2 8.6 14.3 0.79 9.2 0.2 4.1 3 2 4 7 7 7 0 Leucine-rich repeat EIF_2_alpha PF07541.12 KSA03708.1 - 1e-38 132.0 0.1 2e-38 131.0 0.1 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 KSA03708.1 - 3e-15 56.3 1.5 5.7e-15 55.4 1.5 1.5 1 0 0 1 1 1 1 S1 RNA binding domain Amidohydro_1 PF01979.20 KSA03708.1 - 0.073 12.4 0.5 0.11 11.8 0.5 1.3 1 0 0 1 1 1 0 Amidohydrolase family Pkinase PF00069.25 KSA03709.1 - 2.4e-06 27.1 0.1 3.4e-06 26.6 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KSA03709.1 - 3.2e-06 26.6 0.0 4.1e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KSA03710.1 - 2.8e-10 40.0 0.0 3.5e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Flo11 PF10182.9 KSA03710.1 - 0.091 12.9 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 Flo11 domain Rho_GDI PF02115.17 KSA03711.1 - 1.1e-22 80.7 0.4 1.3e-22 80.5 0.4 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Memo PF01875.17 KSA03712.1 - 2.9e-69 233.2 0.0 3.4e-69 233.0 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein Adaptin_N PF01602.20 KSA03713.1 - 3.2e-97 326.3 10.8 3.9e-97 326.0 10.8 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KSA03713.1 - 1.1e-35 123.0 9.6 3.7e-35 121.4 1.5 3.4 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KSA03713.1 - 2.6e-10 40.5 0.0 0.078 13.4 0.1 5.8 4 1 0 5 5 5 2 HEAT repeats HEAT PF02985.22 KSA03713.1 - 9.4e-05 22.4 0.0 16 6.0 0.0 5.5 7 0 0 7 7 7 1 HEAT repeat HEAT_EZ PF13513.6 KSA03713.1 - 0.0002 21.8 1.2 3.2 8.4 0.2 4.9 4 2 1 5 5 5 2 HEAT-like repeat RasGEF_N_2 PF14663.6 KSA03713.1 - 0.0034 17.8 0.9 0.037 14.4 0.2 2.9 1 1 1 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain Arm PF00514.23 KSA03713.1 - 0.0093 16.0 0.2 0.43 10.7 0.2 3.8 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat CBF PF03914.17 KSA03713.1 - 0.05 13.6 1.1 46 4.0 0.1 3.4 3 0 0 3 3 3 0 CBF/Mak21 family RTP1_C1 PF10363.9 KSA03713.1 - 0.06 13.5 1.5 0.85 9.8 1.5 2.7 1 1 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 1 DEAD PF00270.29 KSA03714.1 - 5.1e-25 88.3 0.0 8.5e-23 81.0 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase DUF1998 PF09369.10 KSA03714.1 - 5.7e-17 62.3 1.1 7.6e-16 58.6 0.2 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF1998) Helicase_C PF00271.31 KSA03714.1 - 1.7e-14 54.1 0.1 1.3e-13 51.2 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KSA03714.1 - 3.6e-08 33.6 0.1 1.1e-06 28.8 0.1 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 KSA03714.1 - 0.056 12.5 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Cellulase PF00150.18 KSA03715.1 - 2.6e-11 43.5 2.9 2.6e-11 43.5 2.9 1.6 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) UCH PF00443.29 KSA03716.1 - 3.9e-61 206.8 3.7 3.9e-61 206.8 3.7 1.9 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KSA03716.1 - 6.8e-24 85.0 1.5 6.8e-24 85.0 1.5 2.3 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.20 KSA03716.1 - 0.022 15.3 0.3 0.13 12.8 0.3 2.3 1 1 0 1 1 1 0 Rhodanese-like domain Y_phosphatase2 PF03162.13 KSA03717.1 - 2.6e-43 147.5 0.0 3.2e-43 147.2 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 KSA03717.1 - 0.069 12.7 0.0 0.086 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Aminotran_1_2 PF00155.21 KSA03718.1 - 1.4e-62 212.0 0.0 1.6e-62 211.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KSA03718.1 - 0.0011 18.0 0.0 0.0015 17.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KSA03718.1 - 0.0034 16.8 0.0 0.029 13.7 0.0 2.3 2 1 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family OKR_DC_1 PF01276.20 KSA03718.1 - 0.0076 15.0 0.0 0.014 14.2 0.0 1.3 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain ABC_tran PF00005.27 KSA03719.1 - 7.6e-22 78.3 0.4 4.1e-11 43.6 0.1 3.5 3 1 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 KSA03719.1 - 1.5e-07 31.6 0.3 0.0017 18.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 KSA03719.1 - 0.0014 18.8 0.0 0.097 12.9 0.0 2.4 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 KSA03719.1 - 0.048 13.4 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 KSA03719.1 - 0.13 12.5 0.8 6.5 7.0 0.5 3.0 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KSA03719.1 - 0.31 11.5 3.2 0.17 12.3 0.5 2.0 2 1 0 2 2 2 0 AAA domain BSD PF03909.17 KSA03720.1 - 1.9e-15 56.6 0.8 5.5e-15 55.1 0.8 1.9 1 0 0 1 1 1 1 BSD domain Baculo_PEP_C PF04513.12 KSA03720.1 - 0.09 12.8 9.6 0.12 12.4 6.4 2.4 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Globin PF00042.22 KSA03720.1 - 0.14 12.8 2.1 1.3 9.6 0.3 2.7 2 1 1 3 3 3 0 Globin DUF4487 PF14868.6 KSA03720.1 - 0.19 10.5 8.8 0.082 11.7 4.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4487) Laminin_II PF06009.12 KSA03720.1 - 6.7 6.7 12.3 2.3 8.2 6.4 3.1 3 1 0 3 3 3 0 Laminin Domain II Response_reg PF00072.24 KSA03721.1 - 3e-18 66.0 0.0 1.8e-12 47.4 0.0 2.5 2 0 0 2 2 2 2 Response regulator receiver domain Ubiquitin_4 PF18036.1 KSA03721.1 - 0.017 15.2 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain PH_5 PF15405.6 KSA03721.1 - 2.2 8.4 5.9 0.97 9.5 1.5 2.7 2 0 0 2 2 2 0 Pleckstrin homology domain LSM PF01423.22 KSA03722.1 - 7.9e-19 67.1 0.5 9.5e-19 66.9 0.5 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KSA03722.1 - 2.3e-05 24.4 0.2 3.3e-05 23.9 0.2 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 KSA03722.1 - 0.011 15.8 0.1 0.016 15.3 0.1 1.3 1 0 0 1 1 1 0 Scd6-like Sm domain Asp_protease PF09668.10 KSA03723.1 - 9.9e-50 167.5 0.1 1.5e-49 166.9 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KSA03723.1 - 3e-18 66.2 0.0 7.6e-18 64.9 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KSA03723.1 - 5.4e-09 36.6 0.2 2.7e-08 34.3 0.0 2.3 2 0 0 2 2 2 1 Aspartyl protease ubiquitin PF00240.23 KSA03723.1 - 5.4e-07 29.3 0.1 1.1e-06 28.3 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 KSA03723.1 - 1e-06 28.5 0.0 2.5e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain RVP PF00077.20 KSA03723.1 - 1.1e-05 25.7 0.1 4.1e-05 23.8 0.1 2.0 1 1 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.11 KSA03723.1 - 0.0021 17.8 0.0 0.0046 16.7 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease UBA_4 PF14555.6 KSA03723.1 - 0.0033 17.2 0.0 0.0091 15.8 0.0 1.8 1 0 0 1 1 1 1 UBA-like domain UN_NPL4 PF11543.8 KSA03723.1 - 0.061 13.8 0.0 0.19 12.3 0.0 1.8 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 AMNp_N PF10423.9 KSA03723.1 - 0.067 12.8 0.1 0.16 11.6 0.0 1.6 2 0 0 2 2 2 0 Bacterial AMP nucleoside phosphorylase N-terminus Aldo_ket_red PF00248.21 KSA03724.1 - 5.5e-43 147.2 0.0 7.2e-43 146.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DUF3866 PF12982.7 KSA03724.1 - 0.24 10.5 0.0 3.1 6.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3866) GDI PF00996.18 KSA03725.1 - 9.4e-220 729.6 0.1 1.1e-219 729.4 0.1 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor Peptidase_M24 PF00557.24 KSA03726.1 - 2.5e-58 197.2 0.0 3.2e-58 196.8 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KSA03726.1 - 2e-20 72.8 0.1 5.2e-20 71.4 0.0 1.7 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain Bromodomain PF00439.25 KSA03726.1 - 0.037 14.1 0.1 0.15 12.1 0.0 2.0 2 0 0 2 2 2 0 Bromodomain UPF0179 PF03684.13 KSA03726.1 - 0.49 10.3 3.4 0.2 11.5 0.2 1.9 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0179) JAB PF01398.21 KSA03727.1 - 1.9e-32 111.7 0.2 1.9e-32 111.7 0.2 1.7 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 KSA03727.1 - 1.2e-13 51.5 1.6 2.4e-13 50.5 1.6 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 KSA03727.1 - 1.1e-07 31.7 0.0 1.6e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain LamB PF02264.15 KSA03727.1 - 0.098 12.5 1.3 0.2 11.5 1.3 1.6 1 1 0 1 1 1 0 LamB porin Sas6_CC PF18594.1 KSA03727.1 - 0.15 11.8 3.6 0.36 10.6 3.6 1.6 1 0 0 1 1 1 0 Sas6/XLF/XRCC4 coiled-coil domain UCH PF00443.29 KSA03728.1 - 2.2e-22 79.8 0.2 3.5e-22 79.1 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KSA03728.1 - 3.7e-11 43.2 0.9 8.9e-11 42.0 0.9 1.6 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 KSA03728.1 - 0.036 13.7 4.3 0.042 13.4 2.1 2.5 2 1 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase SAM35 PF10806.8 KSA03729.1 - 4.2e-39 133.7 0.1 7.5e-39 132.9 0.1 1.4 1 0 0 1 1 1 1 SAM35, subunit of SAM coomplex Tom37 PF10568.9 KSA03729.1 - 0.013 15.8 0.1 0.033 14.5 0.1 1.6 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein Acetyltransf_10 PF13673.7 KSA03730.1 - 2.2e-16 60.0 0.0 2.8e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KSA03730.1 - 3.5e-14 53.0 0.1 8.8e-14 51.7 0.1 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KSA03730.1 - 1.5e-07 31.7 0.0 2.2e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KSA03730.1 - 0.0045 16.9 0.0 0.0085 16.0 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 KSA03730.1 - 0.036 14.1 0.0 1.3 9.1 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 KSA03730.1 - 0.084 12.3 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Putative acetyl-transferase Acetyltransf_8 PF13523.6 KSA03730.1 - 0.18 11.5 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain CAF1C_H4-bd PF12265.8 KSA03731.1 - 5.8e-23 80.9 0.3 1.7e-22 79.5 0.3 1.8 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 KSA03731.1 - 1.9e-18 66.5 9.7 3.4e-05 24.5 0.1 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat BING4CT PF08149.11 KSA03731.1 - 0.00044 20.0 0.1 3.9 7.4 0.0 3.8 4 0 0 4 4 4 2 BING4CT (NUC141) domain TNRC6-PABC_bdg PF16608.5 KSA03731.1 - 0.0066 16.2 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 TNRC6-PABC binding domain Sulfate_transp PF00916.20 KSA03732.1 - 9.6e-77 258.3 15.0 1.3e-76 257.8 15.0 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KSA03732.1 - 7e-17 61.1 0.1 1.8e-16 59.8 0.1 1.6 1 0 0 1 1 1 1 STAS domain ETF PF01012.21 KSA03733.1 - 2.6e-39 135.0 0.0 4.5e-39 134.2 0.0 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 KSA03733.1 - 4.1e-34 116.5 0.8 8.9e-34 115.4 0.3 1.9 2 0 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain Fungal_trans PF04082.18 KSA03735.1 - 4.7e-14 52.1 0.0 1.2e-13 50.7 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KSA03735.1 - 3.9e-06 26.9 8.4 6.3e-06 26.2 8.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TMF_DNA_bd PF12329.8 KSA03735.1 - 4.1 7.5 9.7 0.75 9.8 2.4 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding CAP PF00188.26 KSA03736.1 - 4.9e-21 75.9 5.0 4.9e-21 75.9 5.0 1.6 2 0 0 2 2 2 1 Cysteine-rich secretory protein family AAA_12 PF13087.6 KSA03737.1 - 8.4e-61 205.1 0.7 4.8e-60 202.6 0.0 2.4 2 1 1 3 3 3 1 AAA domain AAA_11 PF13086.6 KSA03737.1 - 2e-56 191.7 0.0 2e-56 191.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KSA03737.1 - 3.2e-11 43.7 0.0 1.7e-09 38.2 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KSA03737.1 - 5.9e-10 39.2 0.0 7.1e-08 32.4 0.0 2.9 3 0 0 3 3 3 1 AAA domain Viral_helicase1 PF01443.18 KSA03737.1 - 3.9e-09 36.6 0.1 0.011 15.5 0.0 3.6 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 KSA03737.1 - 5e-07 29.9 3.6 9.5e-07 29.0 0.2 2.9 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit PhoH PF02562.16 KSA03737.1 - 1.5e-05 24.6 0.0 0.0065 16.0 0.0 2.9 3 0 0 3 3 3 1 PhoH-like protein AAA_22 PF13401.6 KSA03737.1 - 1.7e-05 25.1 0.0 8.2e-05 22.9 0.0 2.2 1 1 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 KSA03737.1 - 5.3e-05 23.1 0.0 0.00019 21.3 0.0 2.0 1 0 0 1 1 1 1 Helicase AAA_5 PF07728.14 KSA03737.1 - 0.0005 20.1 0.1 0.0029 17.6 0.0 2.3 2 1 1 3 3 3 1 AAA domain (dynein-related subfamily) DUF2075 PF09848.9 KSA03737.1 - 0.0027 17.0 1.2 0.0049 16.2 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) T2SSE PF00437.20 KSA03737.1 - 0.0042 16.2 0.1 0.008 15.3 0.1 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_33 PF13671.6 KSA03737.1 - 0.0049 17.0 0.0 0.011 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KSA03737.1 - 0.0056 17.1 0.0 0.015 15.7 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 KSA03737.1 - 0.0058 17.2 1.0 0.014 16.0 0.0 2.2 2 0 0 2 2 2 1 ABC transporter AAA PF00004.29 KSA03737.1 - 0.0063 16.9 0.0 0.02 15.3 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF4844 PF16133.5 KSA03737.1 - 0.03 14.9 0.6 0.11 13.1 0.2 2.3 1 1 1 2 2 1 0 Domain of unknown function (DUF4844) AAA_18 PF13238.6 KSA03737.1 - 0.033 14.7 0.6 0.2 12.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain UvrD_C_2 PF13538.6 KSA03737.1 - 0.052 13.4 0.0 0.094 12.6 0.0 1.5 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_25 PF13481.6 KSA03737.1 - 0.17 11.4 0.0 0.38 10.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Hydin_ADK PF17213.3 KSA03737.1 - 6.2 7.1 9.1 1.7 8.9 0.1 2.7 2 1 0 2 2 2 0 Hydin Adenylate kinase-like domain Npa1 PF11707.8 KSA03738.1 - 2.5e-74 250.7 12.8 2.5e-74 250.7 12.8 2.9 4 0 0 4 4 4 1 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 KSA03738.1 - 1.2e-49 168.7 0.7 1.2e-49 168.7 0.7 3.3 5 0 0 5 5 5 1 Nucleolar pre-ribosomal-associated protein 1 Pkinase PF00069.25 KSA03739.1 - 1.6e-72 244.0 0.0 2.8e-72 243.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KSA03739.1 - 1.5e-31 109.6 0.0 3e-31 108.6 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KSA03739.1 - 0.0036 16.7 0.1 0.41 9.9 0.0 2.4 2 1 0 2 2 2 2 Kinase-like PI3K_1B_p101 PF10486.9 KSA03739.1 - 5.4 4.7 8.3 7.6 4.2 8.3 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Glutaredoxin PF00462.24 KSA03740.1 - 1.8e-15 56.9 0.0 2.3e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin ABC_tran PF00005.27 KSA03741.1 - 2.7e-50 170.4 5.0 8.3e-25 87.9 0.1 2.8 3 0 0 3 3 2 2 ABC transporter ABC2_membrane PF01061.24 KSA03741.1 - 9.3e-42 142.8 38.4 2.1e-22 79.6 11.5 2.3 2 0 0 2 2 2 2 ABC-2 type transporter RsgA_GTPase PF03193.16 KSA03741.1 - 1.4e-11 44.6 3.9 8.2e-05 22.6 1.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 KSA03741.1 - 2.9e-11 43.8 16.4 0.0011 18.9 0.0 4.5 2 2 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KSA03741.1 - 7.8e-08 32.7 0.5 0.033 14.5 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KSA03741.1 - 9.1e-08 32.7 0.5 0.0055 17.1 0.0 2.7 2 1 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 KSA03741.1 - 3.4e-07 29.9 9.7 0.00093 18.7 0.3 3.7 3 1 0 3 3 2 2 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 KSA03741.1 - 6.4e-07 29.8 0.4 0.02 15.1 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KSA03741.1 - 6.8e-07 28.9 1.1 0.016 15.0 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SSE PF00437.20 KSA03741.1 - 2.1e-06 27.0 0.6 0.012 14.6 0.2 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_23 PF13476.6 KSA03741.1 - 2.9e-06 27.9 10.2 0.016 15.7 0.1 3.7 3 1 0 3 3 3 2 AAA domain Rad17 PF03215.15 KSA03741.1 - 8e-06 25.9 0.1 0.15 12.0 0.0 2.6 2 0 0 2 2 2 2 Rad17 P-loop domain RNA_helicase PF00910.22 KSA03741.1 - 9.6e-06 26.0 0.4 0.0065 16.8 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_18 PF13238.6 KSA03741.1 - 1.1e-05 25.9 3.3 0.053 14.1 0.0 3.1 4 0 0 4 4 2 2 AAA domain AAA_30 PF13604.6 KSA03741.1 - 4.2e-05 23.4 0.0 0.35 10.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain cobW PF02492.19 KSA03741.1 - 5.1e-05 22.9 0.7 0.22 11.1 0.0 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain ATPase_2 PF01637.18 KSA03741.1 - 7.4e-05 22.8 4.2 0.046 13.6 0.0 3.3 3 0 0 3 3 3 2 ATPase domain predominantly from Archaea NACHT PF05729.12 KSA03741.1 - 8.2e-05 22.6 0.1 0.24 11.3 0.0 2.8 3 0 0 3 3 2 2 NACHT domain SbcCD_C PF13558.6 KSA03741.1 - 0.00012 22.2 0.3 1.7 8.9 0.1 3.7 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA PF00004.29 KSA03741.1 - 0.00029 21.2 1.6 2.7 8.4 0.0 4.0 4 1 0 4 4 2 2 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 KSA03741.1 - 0.0003 20.9 3.7 0.25 11.4 0.1 3.3 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_24 PF13479.6 KSA03741.1 - 0.00032 20.5 0.4 0.33 10.7 0.1 2.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KSA03741.1 - 0.00036 20.7 0.1 0.24 11.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain Septin PF00735.18 KSA03741.1 - 0.00051 19.4 0.2 0.13 11.6 0.1 2.5 2 0 0 2 2 2 1 Septin AAA_14 PF13173.6 KSA03741.1 - 0.0011 19.0 0.2 2 8.5 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KSA03741.1 - 0.0012 19.2 0.0 0.44 10.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.25 KSA03741.1 - 0.0016 18.1 0.0 0.04 13.6 0.0 2.2 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain Pox_A32 PF04665.12 KSA03741.1 - 0.0019 17.7 0.4 0.16 11.4 0.1 2.5 2 0 0 2 2 2 1 Poxvirus A32 protein NB-ARC PF00931.22 KSA03741.1 - 0.0026 17.0 0.3 0.91 8.7 0.0 2.6 2 0 0 2 2 2 1 NB-ARC domain AAA_5 PF07728.14 KSA03741.1 - 0.0029 17.6 0.2 5 7.1 0.0 3.3 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) ABC2_membrane_2 PF12679.7 KSA03741.1 - 0.0031 16.8 1.5 0.0031 16.8 1.5 2.5 2 0 0 2 2 2 1 ABC-2 family transporter protein AAA_25 PF13481.6 KSA03741.1 - 0.0033 17.0 0.0 1.2 8.7 0.0 2.7 3 0 0 3 3 2 1 AAA domain PduV-EutP PF10662.9 KSA03741.1 - 0.004 16.9 0.3 2.7 7.7 0.1 2.6 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.15 KSA03741.1 - 0.0043 17.0 0.3 3.1 7.7 0.1 2.8 2 0 0 2 2 2 1 NTPase ATP_bind_1 PF03029.17 KSA03741.1 - 0.0044 16.8 0.2 0.57 9.9 0.1 2.5 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein MobB PF03205.14 KSA03741.1 - 0.007 16.3 0.3 1.6 8.7 0.1 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B SRP54 PF00448.22 KSA03741.1 - 0.009 15.7 0.7 4.5 6.9 0.0 2.7 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain PRK PF00485.18 KSA03741.1 - 0.0092 15.7 0.1 0.62 9.8 0.0 2.5 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family dNK PF01712.19 KSA03741.1 - 0.013 15.4 0.6 2.4 8.0 0.2 2.4 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA_7 PF12775.7 KSA03741.1 - 0.013 15.0 0.5 3 7.3 0.0 2.6 2 0 0 2 2 2 0 P-loop containing dynein motor region SRPRB PF09439.10 KSA03741.1 - 0.014 14.9 5.6 0.26 10.7 0.2 2.9 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit IstB_IS21 PF01695.17 KSA03741.1 - 0.015 15.0 0.1 17 5.1 0.0 3.6 5 0 0 5 5 4 0 IstB-like ATP binding protein Zeta_toxin PF06414.12 KSA03741.1 - 0.017 14.4 0.0 5.2 6.3 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin FtsK_SpoIIIE PF01580.18 KSA03741.1 - 0.023 14.1 0.6 0.15 11.4 0.1 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_17 PF13207.6 KSA03741.1 - 0.032 14.7 0.0 0.89 10.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 KSA03741.1 - 0.033 14.2 0.2 3.9 7.5 0.1 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Roc PF08477.13 KSA03741.1 - 0.036 14.3 2.7 3.5 7.9 0.1 2.9 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_13 PF13166.6 KSA03741.1 - 0.044 12.4 11.2 0.62 8.6 0.2 3.6 4 0 0 4 4 3 0 AAA domain S_100 PF01023.19 KSA03741.1 - 0.046 13.4 0.1 0.094 12.4 0.1 1.6 1 0 0 1 1 1 0 S-100/ICaBP type calcium binding domain RuvB_N PF05496.12 KSA03741.1 - 0.055 13.2 0.0 0.83 9.4 0.0 2.4 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain DUF2075 PF09848.9 KSA03741.1 - 0.074 12.3 0.1 7.5 5.7 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.6 KSA03741.1 - 0.1 12.4 2.4 4.4 7.0 0.0 3.1 3 0 0 3 3 3 0 AAA domain GTP_EFTU PF00009.27 KSA03741.1 - 0.12 12.0 0.1 2.6 7.5 0.1 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain VirE PF05272.11 KSA03741.1 - 0.27 10.9 1.6 1.5 8.5 0.0 2.5 3 0 0 3 3 2 0 Virulence-associated protein E DUF87 PF01935.17 KSA03741.1 - 0.37 10.9 8.6 3.8 7.6 0.2 3.6 3 0 0 3 3 3 0 Helicase HerA, central domain PAP2_3 PF14378.6 KSA03742.1 - 3.4e-18 66.0 15.7 5.1e-18 65.5 15.7 1.2 1 0 0 1 1 1 1 PAP2 superfamily PAP2 PF01569.21 KSA03742.1 - 7e-14 51.8 5.5 7e-14 51.8 5.5 2.5 2 1 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 KSA03742.1 - 0.0002 21.8 10.0 0.0002 21.8 10.0 2.6 2 0 0 2 2 2 1 PAP2 superfamily C-terminal PSY3 PF16836.5 KSA03743.1 - 3.2e-15 56.3 0.7 3.4e-15 56.2 0.7 1.1 1 0 0 1 1 1 1 Shu complex component Psy3, DNA-binding description Mt_ATP-synt_D PF05873.12 KSA03744.1 - 7e-19 68.2 5.1 8.2e-19 68.0 5.1 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) Dor1 PF04124.12 KSA03744.1 - 0.0057 15.4 0.9 0.0066 15.2 0.9 1.2 1 0 0 1 1 1 1 Dor1-like family betaPIX_CC PF16523.5 KSA03744.1 - 0.02 14.7 1.1 0.042 13.7 1.1 1.5 1 0 0 1 1 1 0 betaPIX coiled coil ORF_12_N PF18042.1 KSA03744.1 - 0.082 13.3 0.1 0.17 12.3 0.1 1.5 1 0 0 1 1 1 0 ORF 12 gene product N-terminal Adaptin_N PF01602.20 KSA03745.1 - 1.1e-79 268.4 6.2 1.7e-79 267.8 3.1 2.3 2 1 0 2 2 2 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 KSA03745.1 - 0.00018 21.6 0.0 0.00057 20.1 0.0 1.8 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Cnd1 PF12717.7 KSA03745.1 - 0.02 14.9 0.1 0.68 10.0 0.0 2.9 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 CAP PF00188.26 KSA03746.1 - 1.6e-16 61.2 8.1 1.6e-16 61.2 8.1 2.7 2 2 1 3 3 3 1 Cysteine-rich secretory protein family PseudoU_synth_2 PF00849.22 KSA03747.1 - 1.3e-25 90.4 0.0 2.4e-25 89.5 0.0 1.5 1 0 0 1 1 1 1 RNA pseudouridylate synthase ALS2CR8 PF15299.6 KSA03747.1 - 0.0023 17.9 0.9 0.0045 16.9 0.9 1.4 1 0 0 1 1 1 1 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 WD40 PF00400.32 KSA03749.1 - 1.8e-15 57.0 4.2 1.7e-05 25.5 0.0 6.3 7 1 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KSA03749.1 - 1.3e-07 31.8 0.0 0.017 15.4 0.0 3.9 5 0 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain SH3_2 PF07653.17 KSA03750.1 - 3.4e-11 42.7 0.0 8.7e-11 41.3 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KSA03750.1 - 1.2e-10 41.1 0.2 3.4e-10 39.6 0.2 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KSA03750.1 - 1.5e-09 37.3 0.1 4.4e-09 35.8 0.1 1.9 1 0 0 1 1 1 1 SH3 domain EIIBC-GUT_N PF03612.14 KSA03750.1 - 9.8 5.9 7.5 53 3.5 0.0 2.6 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Anoctamin PF04547.12 KSA03751.1 - 7.5e-74 249.2 16.6 9.8e-74 248.8 16.6 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Ala_racemase_N PF01168.20 KSA03752.1 - 6.7e-27 94.6 0.0 8.2e-27 94.3 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain DHQS PF01959.16 KSA03752.1 - 0.14 11.1 0.0 0.26 10.1 0.0 1.4 1 0 0 1 1 1 0 3-dehydroquinate synthase II La PF05383.17 KSA03753.1 - 4.2e-22 78.0 1.3 3.4e-21 75.0 0.1 2.8 3 0 0 3 3 3 1 La domain RRM_1 PF00076.22 KSA03753.1 - 0.0011 18.8 1.8 0.017 15.0 1.8 2.4 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRAP2 PF07576.12 KSA03753.1 - 0.034 14.4 0.1 0.034 14.4 0.1 2.0 2 0 0 2 2 2 0 BRCA1-associated protein 2 Pol_alpha_B_N PF08418.10 KSA03754.1 - 1.6e-53 182.2 7.2 2.6e-53 181.5 7.2 1.4 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.16 KSA03754.1 - 3.7e-35 121.2 0.1 6.5e-35 120.4 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B ResIII PF04851.15 KSA03755.1 - 2.2e-26 92.9 1.1 9e-26 90.9 0.0 2.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KSA03755.1 - 5.8e-15 55.6 0.1 5.5e-14 52.4 0.0 2.8 2 2 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KSA03755.1 - 2.2e-11 43.9 0.0 4.3e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 KSA03755.1 - 2.7e-07 30.5 1.8 4.2e-07 29.9 0.0 2.1 2 0 0 2 2 2 1 SWI2/SNF2 ATPase AAA_14 PF13173.6 KSA03755.1 - 0.00066 19.7 0.9 0.042 13.9 0.1 2.9 2 0 0 2 2 2 1 AAA domain ERCC3_RAD25_C PF16203.5 KSA03755.1 - 0.0025 17.1 0.0 0.0061 15.8 0.0 1.7 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Flavi_DEAD PF07652.14 KSA03755.1 - 0.0035 17.3 0.0 0.01 15.8 0.0 1.7 2 0 0 2 2 2 1 Flavivirus DEAD domain DUF740 PF05340.12 KSA03755.1 - 5.7 5.6 6.8 0.54 8.9 2.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF740) Peptidase_C13 PF01650.18 KSA03756.1 - 3.1e-45 154.7 0.3 4.7e-45 154.1 0.3 1.3 1 0 0 1 1 1 1 Peptidase C13 family Peptidase_C14 PF00656.22 KSA03756.1 - 0.0015 18.6 0.2 0.0031 17.5 0.2 1.5 1 1 0 1 1 1 1 Caspase domain Dynein_light PF01221.18 KSA03756.1 - 0.021 15.2 0.0 0.057 13.7 0.0 1.7 1 0 0 1 1 1 0 Dynein light chain type 1 Collagen_bind PF05737.12 KSA03756.1 - 0.036 14.3 1.1 0.036 14.3 1.1 1.8 2 0 0 2 2 2 0 Collagen binding domain Jacalin PF01419.17 KSA03756.1 - 0.058 13.3 0.2 0.11 12.4 0.2 1.4 1 0 0 1 1 1 0 Jacalin-like lectin domain CLASP_N PF12348.8 KSA03757.1 - 1e-94 316.4 8.8 1.3e-83 280.1 0.0 3.2 4 0 0 4 4 4 2 CLASP N terminal HEAT PF02985.22 KSA03757.1 - 0.011 15.9 0.0 3.1 8.3 0.0 3.9 3 0 0 3 3 3 0 HEAT repeat STE PF02200.16 KSA03758.1 - 1.6e-59 199.0 1.9 3.3e-59 198.1 1.9 1.5 1 0 0 1 1 1 1 STE like transcription factor Peptidase_M28 PF04389.17 KSA03758.1 - 1.1 8.9 4.6 0.33 10.6 1.5 1.6 2 0 0 2 2 2 0 Peptidase family M28 Say1_Mug180 PF10340.9 KSA03759.1 - 1.5e-28 99.7 0.2 2e-28 99.3 0.2 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_3 PF07859.13 KSA03759.1 - 1.2e-13 51.4 0.0 2e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KSA03759.1 - 0.0058 15.9 0.0 0.0097 15.2 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 mRNA_decap_C PF16741.5 KSA03759.1 - 0.077 12.3 0.6 0.25 10.6 0.0 2.1 2 0 0 2 2 2 0 mRNA-decapping enzyme C-terminus COesterase PF00135.28 KSA03759.1 - 0.13 11.1 0.0 0.4 9.5 0.0 1.7 2 0 0 2 2 2 0 Carboxylesterase family ADK PF00406.22 KSA03760.1 - 1.3e-60 203.9 0.0 1.6e-60 203.6 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KSA03760.1 - 5.7e-22 78.6 0.2 4.5e-21 75.7 0.0 2.0 1 1 1 2 2 2 1 AAA domain ADK_lid PF05191.14 KSA03760.1 - 5.7e-16 58.2 0.0 1.4e-15 56.9 0.0 1.7 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 KSA03760.1 - 1.1e-05 26.0 0.0 2.2e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KSA03760.1 - 0.00013 22.1 0.0 0.0003 21.0 0.0 1.5 2 0 0 2 2 2 1 AAA domain Cytidylate_kin PF02224.18 KSA03760.1 - 0.049 13.4 0.0 0.07 12.9 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase AAA_24 PF13479.6 KSA03760.1 - 0.071 12.8 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain Trimer_CC PF08954.11 KSA03760.1 - 0.1 12.1 0.0 0.28 10.8 0.0 1.7 1 0 0 1 1 1 0 Trimerisation motif CFIA_Pcf11 PF11526.8 KSA03761.1 - 7.3e-15 55.2 6.8 7.3e-15 55.2 6.8 2.7 2 1 0 2 2 2 1 Subunit of cleavage factor IA Pcf11 VHS PF00790.19 KSA03761.1 - 0.0023 17.8 0.4 0.0071 16.2 0.1 2.0 2 0 0 2 2 2 1 VHS domain Cript PF10235.9 KSA03761.1 - 0.0069 16.9 3.0 2.7 8.6 0.1 2.9 3 0 0 3 3 3 2 Microtubule-associated protein CRIPT CTD_bind PF04818.13 KSA03761.1 - 0.022 15.6 0.3 0.056 14.3 0.3 1.7 1 0 0 1 1 1 0 RNA polymerase II-binding domain. DUF4685 PF15737.5 KSA03761.1 - 0.022 15.2 0.1 0.063 13.7 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4685) zf_UBZ PF18439.1 KSA03761.1 - 0.74 9.5 2.4 6 6.5 2.4 2.4 1 1 0 1 1 1 0 Ubiquitin-Binding Zinc Finger Mito_carr PF00153.27 KSA03762.1 - 7.4e-30 102.7 1.4 3.3e-15 55.8 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF2014 PF09427.10 KSA03763.1 - 0.094 12.1 0.1 0.17 11.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2014) Cytochrom_B562 PF07361.11 KSA03763.1 - 0.16 12.6 0.8 9.1 7.0 0.1 2.7 2 0 0 2 2 2 0 Cytochrome b562 NAD_Gly3P_dh_N PF01210.23 KSA03764.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TM1586_NiRdase PF14512.6 KSA03766.1 - 0.058 13.0 0.2 0.094 12.3 0.2 1.3 1 0 0 1 1 1 0 Putative TM nitroreductase Phi-29_GP4 PF05464.11 KSA03766.1 - 0.084 13.2 0.9 0.16 12.2 0.5 1.6 1 1 1 2 2 2 0 Phi-29-like late genes activator (early protein GP4) DUF1773 PF08593.10 KSA03767.1 - 3.7e-11 43.9 0.0 7.3e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function LPP PF04728.13 KSA03767.1 - 0.00037 20.8 0.3 0.0014 19.0 0.3 2.1 1 0 0 1 1 1 1 Lipoprotein leucine-zipper DUF1664 PF07889.12 KSA03767.1 - 0.00068 19.7 0.9 0.0014 18.7 0.9 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 KSA03767.1 - 0.00077 19.5 0.3 0.0011 19.0 0.3 1.3 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Syntaxin PF00804.25 KSA03767.1 - 0.0035 17.1 0.6 0.014 15.1 0.1 2.0 2 0 0 2 2 2 1 Syntaxin HsbA PF12296.8 KSA03767.1 - 0.0058 17.1 0.1 0.012 16.0 0.1 1.6 1 0 0 1 1 1 1 Hydrophobic surface binding protein A DUF4988 PF16378.5 KSA03767.1 - 0.0073 16.0 0.3 0.0073 16.0 0.3 1.5 2 0 0 2 2 2 1 Domain of unknown function XhlA PF10779.9 KSA03767.1 - 0.016 15.4 1.7 0.033 14.4 0.1 2.1 2 0 0 2 2 2 0 Haemolysin XhlA Filament PF00038.21 KSA03767.1 - 0.032 13.8 0.0 0.05 13.2 0.0 1.3 1 0 0 1 1 1 0 Intermediate filament protein TLE_N PF03920.15 KSA03767.1 - 0.062 13.4 0.0 0.16 12.0 0.0 1.6 1 1 0 1 1 1 0 Groucho/TLE N-terminal Q-rich domain DUF2746 PF10874.8 KSA03767.1 - 0.07 13.6 0.1 0.17 12.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2746) FlaC_arch PF05377.11 KSA03767.1 - 0.081 13.3 7.0 0.27 11.6 3.8 2.7 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF1640 PF07798.11 KSA03767.1 - 0.085 12.9 0.2 0.15 12.1 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) WEMBL PF05701.11 KSA03767.1 - 0.2 10.3 0.0 0.23 10.1 0.0 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Rieske PF00355.26 KSA03768.1 - 4.7e-11 42.5 0.0 7.8e-11 41.8 0.0 1.4 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.14 KSA03768.1 - 1.3e-10 41.6 0.1 3.1e-10 40.4 0.1 1.7 1 1 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region HECT PF00632.25 KSA03769.1 - 1.4e-83 280.9 0.4 2.8e-83 279.9 0.4 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) zf-LSD1 PF06943.12 KSA03769.1 - 0.89 9.5 5.6 1.7 8.5 5.6 1.5 1 0 0 1 1 1 0 LSD1 zinc finger Adeno_E4 PF05385.11 KSA03770.1 - 0.089 12.9 0.1 0.19 11.8 0.1 1.5 1 0 0 1 1 1 0 Mastadenovirus early E4 13 kDa protein Nucleopor_Nup85 PF07575.13 KSA03771.1 - 5.2e-88 296.0 14.3 7.6e-88 295.5 14.3 1.2 1 0 0 1 1 1 1 Nup85 Nucleoporin Atg8 PF02991.16 KSA03771.1 - 0.084 13.1 0.1 2.4 8.4 0.0 2.5 2 0 0 2 2 2 0 Autophagy protein Atg8 ubiquitin like ATP-synt_C PF00137.21 KSA03772.1 - 2.9e-35 120.4 31.7 1.8e-22 79.4 13.6 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Tetraspanin PF00335.20 KSA03772.1 - 0.86 9.3 5.8 1.4 8.6 5.8 1.3 1 0 0 1 1 1 0 Tetraspanin family DUF2970 PF11174.8 KSA03772.1 - 4.2 7.3 10.8 0.95 9.4 1.7 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) Ribosomal_L7Ae PF01248.26 KSA03773.1 - 1.7e-26 91.7 0.0 2.1e-26 91.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 KSA03773.1 - 0.00036 20.4 0.0 0.0005 19.9 0.0 1.3 1 0 0 1 1 1 1 PELOTA RNA binding domain RNase_P_pop3 PF08228.11 KSA03773.1 - 0.0021 18.1 0.0 0.0024 17.9 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 Pico_P2B PF01552.17 KSA03773.1 - 0.039 14.1 0.0 0.063 13.4 0.0 1.3 1 0 0 1 1 1 0 Picornavirus 2B protein Urb2 PF10441.9 KSA03774.1 - 2.7e-59 200.6 5.7 2.7e-59 200.6 5.7 2.4 3 0 0 3 3 3 1 Urb2/Npa2 family Bcl-2 PF00452.19 KSA03774.1 - 0.041 14.6 0.4 0.93 10.2 0.0 3.1 3 0 0 3 3 3 0 Apoptosis regulator proteins, Bcl-2 family Voltage_CLC PF00654.20 KSA03775.1 - 4.4e-84 282.7 28.5 8e-84 281.9 24.0 2.1 2 0 0 2 2 2 2 Voltage gated chloride channel CBS PF00571.28 KSA03775.1 - 9e-13 48.5 0.0 1.6e-06 28.5 0.1 3.0 3 0 0 3 3 3 2 CBS domain DUF4064 PF13273.6 KSA03775.1 - 4 7.8 15.1 0.1 12.9 4.0 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF4064) AATase PF07247.12 KSA03776.1 - 5.3e-32 111.0 4.5 4.5e-31 108.0 4.5 2.5 1 1 0 1 1 1 1 Alcohol acetyltransferase Syntaxin_2 PF14523.6 KSA03778.1 - 9.3e-24 83.7 7.5 9.3e-24 83.7 7.5 2.9 2 1 0 2 2 2 2 Syntaxin-like protein SNARE PF05739.19 KSA03778.1 - 2.2e-12 46.7 0.2 7.1e-12 45.1 0.2 1.9 1 0 0 1 1 1 1 SNARE domain Synaptobrevin PF00957.21 KSA03778.1 - 0.00036 20.3 1.3 0.00036 20.3 1.3 3.2 5 0 0 5 5 5 1 Synaptobrevin Vac7 PF12751.7 KSA03778.1 - 0.016 14.7 10.1 0.24 10.8 4.7 2.2 2 1 0 2 2 2 0 Vacuolar segregation subunit 7 Chordopox_A33R PF05966.12 KSA03778.1 - 0.025 13.9 0.4 3.8 6.7 0.1 2.3 2 0 0 2 2 2 0 Chordopoxvirus A33R protein Orf78 PF06024.12 KSA03778.1 - 0.66 10.3 0.1 0.66 10.3 0.1 3.2 3 1 0 3 3 3 0 Orf78 (ac78) TerB_C PF15615.6 KSA03779.1 - 0.47 10.8 2.8 5.3 7.3 2.8 2.1 1 1 0 1 1 1 0 TerB-C domain DNA_pol_B PF00136.21 KSA03780.1 - 4.2e-121 404.8 4.0 4.2e-121 404.8 4.0 1.6 2 0 0 2 2 2 1 DNA polymerase family B zf-DNA_Pol PF08996.10 KSA03780.1 - 3.8e-64 215.8 2.8 7.6e-64 214.9 2.8 1.5 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 KSA03780.1 - 1.1e-39 136.5 0.0 2.5e-39 135.4 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.8 KSA03780.1 - 1.1e-21 76.7 9.7 4.6e-21 74.7 9.7 2.2 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal DUF1744 PF08490.12 KSA03780.1 - 0.037 12.6 0.1 0.077 11.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1744) SNF5 PF04855.12 KSA03781.1 - 7e-46 156.9 10.4 2.6e-29 102.7 0.0 3.0 2 1 1 3 3 3 2 SNF5 / SMARCB1 / INI1 adh_short PF00106.25 KSA03782.1 - 5.6e-42 143.4 0.1 6.8e-42 143.1 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KSA03782.1 - 5.9e-32 111.1 0.0 8.1e-32 110.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KSA03782.1 - 1.4e-05 25.0 0.0 3.5e-05 23.8 0.0 1.5 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 KSA03782.1 - 0.0027 17.1 0.0 0.0051 16.2 0.0 1.4 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) GDP_Man_Dehyd PF16363.5 KSA03782.1 - 0.1 11.9 0.0 0.2 11.0 0.0 1.5 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase DUF2370 PF10176.9 KSA03783.1 - 4e-84 281.8 0.0 4e-84 281.8 0.0 1.8 2 1 0 2 2 2 1 Protein of unknown function (DUF2370) Mito_carr PF00153.27 KSA03784.1 - 1.1e-59 198.4 5.7 3.6e-21 74.9 0.4 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KSA03784.1 - 0.0013 18.0 0.2 0.39 9.8 0.0 2.5 2 1 0 2 2 2 2 Gammaproteobacterial serine protease YtxH PF12732.7 KSA03784.1 - 0.95 10.0 0.0 0.95 10.0 0.0 2.9 3 0 0 3 3 3 0 YtxH-like protein TFIIE_alpha PF02002.17 KSA03785.1 - 1.1e-19 70.3 3.7 2.7e-19 68.9 1.3 2.2 2 0 0 2 2 2 1 TFIIE alpha subunit TF_Zn_Ribbon PF08271.12 KSA03785.1 - 0.00026 20.5 0.7 0.0006 19.3 0.2 2.0 2 0 0 2 2 2 1 TFIIB zinc-binding zf_UBZ PF18439.1 KSA03785.1 - 0.0035 16.9 0.6 0.081 12.5 0.1 2.5 2 0 0 2 2 2 1 Ubiquitin-Binding Zinc Finger zf-TFIIB PF13453.6 KSA03785.1 - 0.0068 15.7 0.4 0.016 14.6 0.4 1.7 1 0 0 1 1 1 1 Transcription factor zinc-finger zf-ribbon_3 PF13248.6 KSA03785.1 - 0.007 15.7 1.2 1.3 8.5 0.1 2.6 2 0 0 2 2 2 2 zinc-ribbon domain OrfB_Zn_ribbon PF07282.11 KSA03785.1 - 0.0075 16.2 0.2 0.017 15.0 0.2 1.6 1 0 0 1 1 1 1 Putative transposase DNA-binding domain Zn_Tnp_IS1595 PF12760.7 KSA03785.1 - 0.014 15.3 0.1 0.03 14.3 0.1 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zinc_ribbon_2 PF13240.6 KSA03785.1 - 0.042 13.6 1.6 1.2 9.0 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.7 KSA03785.1 - 0.045 13.8 0.2 0.089 12.8 0.2 1.5 1 0 0 1 1 1 0 Double zinc ribbon NodS PF05401.11 KSA03785.1 - 0.051 13.2 0.0 0.082 12.5 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) Zn-ribbon_8 PF09723.10 KSA03785.1 - 0.091 12.9 1.2 0.33 11.1 1.1 2.0 1 1 1 2 2 2 0 Zinc ribbon domain DUF2387 PF09526.10 KSA03785.1 - 0.14 12.3 1.3 0.24 11.6 0.1 2.0 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) zf-Di19 PF05605.12 KSA03785.1 - 0.17 12.2 0.2 4.5 7.6 0.0 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-CCHC_2 PF13696.6 KSA03785.1 - 0.28 11.1 2.2 0.54 10.1 2.2 1.5 1 0 0 1 1 1 0 Zinc knuckle Sgf11 PF08209.11 KSA03785.1 - 2.1 8.0 3.8 12 5.6 0.2 2.3 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) U1snRNP70_N PF12220.8 KSA03785.1 - 9.4 6.9 8.9 10 6.8 5.5 2.7 2 1 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Forkhead PF00250.18 KSA03786.1 - 9.9e-36 121.9 1.7 1.3e-35 121.5 0.2 2.1 2 0 0 2 2 2 1 Forkhead domain PBP1_TM PF14812.6 KSA03786.1 - 1.2 9.5 7.1 1.4 9.4 1.3 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal G10 PF01125.17 KSA03787.1 - 1.1e-58 197.2 10.8 1.2e-58 197.0 10.8 1.0 1 0 0 1 1 1 1 G10 protein DUF1257 PF06868.11 KSA03787.1 - 0.033 14.4 0.2 0.056 13.7 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1257) RSN1_7TM PF02714.15 KSA03788.1 - 1.1e-93 313.5 23.9 1.1e-93 313.5 23.9 1.6 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KSA03788.1 - 1.1e-39 135.7 2.0 1.1e-39 135.7 2.0 2.5 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KSA03788.1 - 6.2e-32 111.2 0.3 1e-31 110.5 0.3 1.4 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 KSA03788.1 - 8.4e-26 90.0 0.0 1.7e-25 89.0 0.0 1.6 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter RRM_1 PF00076.22 KSA03788.1 - 0.059 13.2 0.0 0.21 11.4 0.0 1.9 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lactamase_B PF00753.27 KSA03789.1 - 1.9e-27 96.6 0.2 2.5e-27 96.1 0.2 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KSA03789.1 - 8.9e-05 22.1 0.1 0.00017 21.2 0.1 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Pyrophosphatase PF00719.19 KSA03790.1 - 1.1e-54 184.6 0.1 1.5e-54 184.2 0.1 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase Thioredoxin_10 PF17991.1 KSA03790.1 - 0.18 12.4 0.2 0.94 10.0 0.1 1.9 2 0 0 2 2 2 0 Thioredoxin like C-terminal domain Nup188 PF10487.9 KSA03791.1 - 0 1123.2 47.2 0 1122.1 47.2 1.6 1 0 0 1 1 1 1 Nucleoporin subcomplex protein binding to Pom34 Nup188_C PF18378.1 KSA03791.1 - 5.3e-30 104.5 3.8 5.3e-30 104.5 3.8 1.9 2 0 0 2 2 2 1 Nuclear pore protein NUP188 C-terminal domain PCNA_N PF00705.18 KSA03791.1 - 0.02 14.6 0.0 0.15 11.8 0.0 2.4 2 0 0 2 2 2 0 Proliferating cell nuclear antigen, N-terminal domain UPF0240 PF06784.11 KSA03791.1 - 0.11 12.6 0.3 0.29 11.2 0.3 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0240) GHMP_kinases_N PF00288.26 KSA03792.1 - 2.2e-17 63.1 0.6 6.7e-17 61.5 0.6 1.9 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KSA03792.1 - 7.1e-07 29.5 2.1 7.9e-07 29.4 0.0 2.2 3 0 0 3 3 3 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.9 KSA03792.1 - 0.0015 18.1 0.1 0.003 17.1 0.1 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature Apc13p PF05839.11 KSA03792.1 - 0.11 12.7 0.2 0.29 11.3 0.2 1.7 1 0 0 1 1 1 0 Apc13p protein Mtc PF03820.17 KSA03793.1 - 1.3e-120 402.1 0.9 1.5e-120 402.0 0.9 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier ACPS PF01648.20 KSA03794.1 - 2.4e-13 50.2 0.0 2.9e-13 49.9 0.0 1.1 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily 4PPT_N PF17837.1 KSA03794.1 - 0.18 11.9 0.0 0.34 11.1 0.0 1.5 1 0 0 1 1 1 0 4'-phosphopantetheinyl transferase N-terminal domain GMP_synt_C PF00958.22 KSA03795.1 - 1.9e-43 146.4 0.1 4.3e-43 145.3 0.1 1.6 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 KSA03795.1 - 3.6e-42 144.3 0.0 5.5e-42 143.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.17 KSA03795.1 - 6e-09 35.4 0.1 2.1e-05 23.8 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 KSA03795.1 - 1.1e-08 35.1 0.6 8.3e-08 32.2 0.3 2.5 2 1 0 2 2 2 1 Peptidase C26 QueC PF06508.13 KSA03795.1 - 0.0027 17.2 0.0 0.075 12.5 0.0 2.1 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC PAPS_reduct PF01507.19 KSA03795.1 - 0.023 14.7 0.0 0.038 14.0 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family tRNA_Me_trans PF03054.16 KSA03795.1 - 0.033 13.0 0.0 0.066 12.0 0.0 1.5 2 0 0 2 2 2 0 tRNA methyl transferase ThiI PF02568.14 KSA03795.1 - 0.053 13.1 0.0 0.098 12.2 0.0 1.4 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) ATP_bind_3 PF01171.20 KSA03795.1 - 0.16 11.7 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 PP-loop family NLE PF08154.12 KSA03796.1 - 1.2e-24 86.5 0.2 2.3e-24 85.7 0.2 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain WD40 PF00400.32 KSA03796.1 - 3e-23 81.6 7.9 2.4e-05 25.0 0.3 7.3 7 0 0 7 7 7 4 WD domain, G-beta repeat Nup160 PF11715.8 KSA03796.1 - 4.6e-07 28.9 4.8 0.0056 15.4 0.2 2.4 2 1 0 2 2 2 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KSA03796.1 - 0.18 12.1 0.4 1.3 9.4 0.1 2.7 4 1 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain N2227 PF07942.12 KSA03797.1 - 3.2e-55 187.2 0.4 4.7e-55 186.7 0.4 1.1 1 0 0 1 1 1 1 N2227-like protein PPTA PF01239.22 KSA03798.1 - 4.9e-35 118.2 18.4 5.7e-09 35.4 1.6 5.5 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat TPR_17 PF13431.6 KSA03798.1 - 0.11 12.9 0.6 18 6.0 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat PSCyt2 PF07583.11 KSA03798.1 - 0.33 10.8 2.8 0.71 9.8 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1549) IPPT PF01715.17 KSA03800.1 - 2e-65 220.8 0.3 3e-65 220.2 0.3 1.3 1 0 0 1 1 1 1 IPP transferase zf-met PF12874.7 KSA03800.1 - 0.18 12.2 1.9 3.7 8.1 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type BRO1 PF03097.18 KSA03801.1 - 9e-107 357.2 3.0 9e-107 357.2 3.0 1.8 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 KSA03801.1 - 2e-68 230.9 20.9 4.7e-68 229.7 15.7 2.5 2 0 0 2 2 2 2 ALIX V-shaped domain binding to HIV F_actin_bind PF08919.10 KSA03801.1 - 0.0063 16.6 3.8 2 8.5 0.2 3.9 3 0 0 3 3 3 1 F-actin binding Myb_DNA-binding PF00249.31 KSA03802.1 - 4.2e-22 78.1 4.8 5.2e-10 39.4 0.9 3.0 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KSA03802.1 - 3.2e-20 72.1 5.0 7.1e-12 45.4 1.7 3.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_Cef PF11831.8 KSA03802.1 - 1.2e-12 47.9 7.9 1.2e-12 47.9 7.9 3.8 1 1 3 4 4 4 1 pre-mRNA splicing factor component Rap1_C PF11626.8 KSA03802.1 - 0.0015 18.6 0.4 0.029 14.5 0.0 3.2 3 1 0 3 3 3 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain UME PF08064.13 KSA03803.1 - 0.0056 16.6 0.1 0.029 14.3 0.1 2.2 2 0 0 2 2 2 1 UME (NUC010) domain CAF20 PF17052.5 KSA03804.1 - 9.6e-64 214.3 6.1 1.1e-63 214.2 6.1 1.0 1 0 0 1 1 1 1 Cap associated factor Use1 PF09753.9 KSA03804.1 - 0.049 13.4 1.1 0.06 13.1 1.1 1.1 1 0 0 1 1 1 0 Membrane fusion protein Use1 Pec_lyase_N PF04431.13 KSA03804.1 - 0.051 13.8 2.0 0.092 13.0 2.0 1.7 1 1 0 1 1 1 0 Pectate lyase, N terminus RRP7 PF12923.7 KSA03804.1 - 0.9 9.7 6.7 0.11 12.7 1.4 2.1 1 1 1 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain Tma16 PF11176.8 KSA03805.1 - 6.6e-47 159.1 5.1 7.9e-47 158.8 5.1 1.1 1 0 0 1 1 1 1 Translation machinery-associated protein 16 FMP23 PF17315.2 KSA03806.1 - 3.4e-09 37.0 36.0 0.0019 18.4 2.6 9.8 4 2 2 8 8 8 5 Found in mitochondrial proteome ORF6C PF10552.9 KSA03806.1 - 0.7 10.0 8.3 2.6 8.1 0.1 4.7 5 0 0 5 5 5 0 ORF6C domain RGS PF00615.19 KSA03807.1 - 5.8e-07 29.8 0.3 0.028 14.7 0.1 2.5 2 0 0 2 2 2 2 Regulator of G protein signaling domain NOA36 PF06524.12 KSA03807.1 - 0.74 9.1 6.0 1.1 8.5 6.0 1.2 1 0 0 1 1 1 0 NOA36 protein WD40_3 PF15911.5 KSA03808.1 - 0.072 13.1 0.2 0.73 9.9 0.1 2.6 2 0 0 2 2 2 0 WD domain, G-beta repeat NAT PF04768.13 KSA03809.1 - 3.3e-52 176.6 1.3 1.2e-51 174.7 0.2 2.3 2 1 0 2 2 2 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase Semialdhyde_dh PF01118.24 KSA03809.1 - 1e-31 109.9 0.0 2.4e-31 108.7 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.28 KSA03809.1 - 6.1e-29 101.3 0.1 1.4e-28 100.1 0.0 1.7 2 0 0 2 2 2 1 Amino acid kinase family Semialdhyde_dhC PF02774.18 KSA03809.1 - 1.2e-08 35.2 0.0 3e-08 34.0 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain DapB_N PF01113.20 KSA03809.1 - 0.006 16.7 0.0 0.018 15.1 0.0 1.9 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Y_phosphatase2 PF03162.13 KSA03810.1 - 7.2e-33 113.5 5.8 2.7e-20 72.6 0.8 2.7 3 0 0 3 3 3 2 Tyrosine phosphatase family Mso1_Sec1_bdg PF14475.6 KSA03811.1 - 5.3e-20 70.7 2.2 5.9e-20 70.6 0.1 2.2 2 0 0 2 2 2 1 Sec1-binding region of Mso1 Mso1_C PF14477.6 KSA03811.1 - 1.1e-19 70.5 16.4 1.1e-19 70.5 16.4 3.3 1 1 2 3 3 3 1 Membrane-polarising domain of Mso1 DEAD PF00270.29 KSA03812.1 - 1.3e-34 119.5 0.0 3.2e-34 118.2 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KSA03812.1 - 2.2e-22 79.5 0.1 1.1e-21 77.2 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KSA03812.1 - 1.1e-07 32.1 0.0 2.3e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.14 KSA03812.1 - 0.024 13.9 0.1 0.76 9.0 0.0 2.4 2 0 0 2 2 2 0 SecA DEAD-like domain PGM1_C PF18105.1 KSA03812.1 - 0.12 11.9 0.0 0.35 10.4 0.0 1.8 1 0 0 1 1 1 0 PGM1 C-terminal domain Sad1_UNC PF07738.13 KSA03813.1 - 2.6e-31 108.4 0.1 5.9e-31 107.2 0.1 1.7 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal KRAP_IP3R_bind PF14722.6 KSA03813.1 - 0.36 10.6 0.0 0.36 10.6 0.0 3.9 4 1 0 4 4 4 0 Ki-ras-induced actin-interacting protein-IP3R-interacting domain RAI1 PF08652.11 KSA03814.1 - 6.7e-27 93.5 0.2 3.2e-26 91.3 0.0 2.2 2 0 0 2 2 2 1 RAI1 like PD-(D/E)XK nuclease Catalase PF00199.19 KSA03815.1 - 1.6e-190 633.2 0.2 2.2e-190 632.7 0.2 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 KSA03815.1 - 3.1e-10 40.1 1.2 7.4e-10 38.9 0.1 2.2 3 0 0 3 3 3 1 Catalase-related immune-responsive Torus PF16131.5 KSA03817.1 - 2.2e-36 124.8 0.2 2.2e-36 124.8 0.2 2.3 3 0 0 3 3 3 1 Torus domain RRM_1 PF00076.22 KSA03817.1 - 8.4e-14 51.2 0.3 1.8e-13 50.1 0.1 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KSA03817.1 - 0.0093 15.9 0.1 0.02 14.9 0.1 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 KSA03817.1 - 0.022 14.6 0.0 0.042 13.7 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif RRM_5 PF13893.6 KSA03817.1 - 0.028 14.0 0.0 0.06 12.9 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_4 PF18044.1 KSA03817.1 - 0.057 13.2 8.1 0.092 12.6 8.1 1.3 1 0 0 1 1 1 0 CCCH-type zinc finger Kin17_mid PF10357.9 KSA03817.1 - 0.12 12.2 6.1 1 9.3 6.1 2.3 1 1 0 1 1 1 0 Domain of Kin17 curved DNA-binding protein Sec3_C_2 PF15278.6 KSA03817.1 - 0.24 11.8 2.8 6.1 7.3 0.3 2.5 2 0 0 2 2 2 0 Sec3 exocyst complex subunit zf-CCCH_2 PF14608.6 KSA03817.1 - 9.9 6.8 8.6 4.2 8.0 5.2 2.1 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger DEAD PF00270.29 KSA03818.1 - 9.2e-44 149.3 0.0 1.7e-43 148.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KSA03818.1 - 1e-30 106.4 0.6 4.4e-30 104.3 0.4 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KSA03818.1 - 0.00084 19.4 1.9 0.0012 18.9 0.0 2.2 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit MFS_1 PF07690.16 KSA03819.1 - 1.8e-25 89.6 8.5 1.3e-14 53.9 2.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 KSA03819.1 - 4.7e-11 42.7 7.2 4.7e-11 42.7 7.2 2.2 2 0 0 2 2 2 1 Nodulin-like Sugar_tr PF00083.24 KSA03819.1 - 2.9e-05 23.1 28.6 0.00081 18.4 7.9 3.1 2 1 1 3 3 3 2 Sugar (and other) transporter NAC PF01849.18 KSA03820.1 - 2.4e-17 62.6 0.0 4.9e-17 61.7 0.0 1.5 1 0 0 1 1 1 1 NAC domain Pyridoxal_deC PF00282.19 KSA03821.1 - 4.8e-58 196.7 0.0 8e-58 195.9 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KSA03821.1 - 1.3e-05 24.4 0.0 2.6e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class-V Rota_NSP4 PF01452.16 KSA03821.1 - 0.038 13.7 0.2 0.084 12.5 0.2 1.5 1 0 0 1 1 1 0 Rotavirus non structural protein DUF1774 PF08611.10 KSA03822.1 - 4.6e-32 110.2 3.1 4.6e-32 110.2 3.1 2.9 2 1 1 3 3 2 1 Fungal protein of unknown function (DUF1774) Ac76 PF05814.11 KSA03822.1 - 0.36 10.9 10.6 0.59 10.2 0.8 3.4 3 0 0 3 3 3 0 Orf76 (Ac76) SF3b10 PF07189.11 KSA03823.1 - 1.2e-30 105.4 0.5 1.3e-30 105.3 0.5 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) GATA PF00320.27 KSA03824.1 - 2.3e-15 55.9 5.0 4.1e-15 55.1 5.0 1.5 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.10 KSA03824.1 - 2.5e-05 24.0 0.1 6.2e-05 22.8 0.1 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) TF_Zn_Ribbon PF08271.12 KSA03824.1 - 0.002 17.6 0.9 0.0053 16.3 0.9 1.7 1 0 0 1 1 1 1 TFIIB zinc-binding ArfGap PF01412.18 KSA03824.1 - 0.0079 16.3 0.7 0.0079 16.3 0.7 2.8 3 1 0 3 3 3 1 Putative GTPase activating protein for Arf Elf1 PF05129.13 KSA03824.1 - 0.017 15.1 0.1 0.04 14.0 0.1 1.6 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like eIF-5_eIF-2B PF01873.17 KSA03824.1 - 0.056 13.3 0.7 0.16 11.8 0.7 1.8 1 0 0 1 1 1 0 Domain found in IF2B/IF5 ADH_N PF08240.12 KSA03825.1 - 0.00041 20.2 0.0 0.0013 18.6 0.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KSA03825.1 - 0.0008 19.4 0.0 0.0022 18.0 0.0 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase SlpA PF03217.14 KSA03825.1 - 1.7 9.3 5.2 2.4 8.8 1.0 3.1 4 0 0 4 4 4 0 Surface later protein A domain Sel1 PF08238.12 KSA03826.1 - 1e-10 41.9 5.8 0.0041 17.8 0.0 6.5 7 0 0 7 7 7 3 Sel1 repeat TPR_2 PF07719.17 KSA03826.1 - 8e-05 22.5 2.8 0.053 13.6 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 KSA03826.1 - 8.7e-05 22.4 1.1 0.053 13.8 0.0 5.3 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 KSA03826.1 - 0.001 19.3 0.1 0.001 19.3 0.1 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KSA03826.1 - 0.0015 18.3 7.3 0.021 14.7 0.0 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 KSA03826.1 - 0.059 13.1 0.0 0.059 13.1 0.0 4.8 6 0 0 6 6 6 0 TPR repeat Aa_trans PF01490.18 KSA03827.1 - 4.3e-87 292.5 40.0 5.2e-87 292.2 40.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein ApoO PF09769.9 KSA03828.1 - 1.1e-32 112.7 0.1 1e-31 109.6 0.0 2.0 2 0 0 2 2 2 1 Apolipoprotein O SWIRM PF04433.17 KSA03828.1 - 0.034 14.5 0.6 5.2 7.5 0.1 2.3 2 0 0 2 2 2 0 SWIRM domain ApbA_C PF08546.11 KSA03829.1 - 2.3e-09 37.5 0.0 4.7e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal BLOC1_2 PF10046.9 KSA03829.1 - 0.75 10.1 12.3 0.24 11.7 0.6 2.9 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Thymidylate_kin PF02223.17 KSA03830.1 - 1.6e-38 132.3 0.0 2.6e-38 131.6 0.0 1.3 1 1 0 1 1 1 1 Thymidylate kinase dNK PF01712.19 KSA03830.1 - 0.0003 20.7 0.0 0.0006 19.7 0.0 1.5 1 1 0 1 1 1 1 Deoxynucleoside kinase AAA_18 PF13238.6 KSA03830.1 - 0.0016 19.0 0.0 0.0047 17.5 0.0 1.8 1 1 1 2 2 2 1 AAA domain Plus-3 PF03126.18 KSA03830.1 - 0.098 13.2 0.1 0.19 12.3 0.1 1.5 1 0 0 1 1 1 0 Plus-3 domain Clat_adaptor_s PF01217.20 KSA03831.1 - 7e-49 165.4 4.4 7.8e-49 165.3 4.4 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Ku PF02735.16 KSA03832.1 - 2.2e-30 105.9 0.0 2.2e-30 105.9 0.0 2.5 3 0 0 3 3 3 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 KSA03832.1 - 6.3e-13 49.0 9.7 1.4e-12 47.8 9.7 1.7 1 1 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 KSA03832.1 - 2.1e-05 25.1 1.6 2.1e-05 25.1 1.6 2.7 3 0 0 3 3 3 1 Ku70/Ku80 C-terminal arm SIX1_SD PF16878.5 KSA03833.1 - 0.064 13.8 0.5 0.55 10.8 0.0 2.5 1 1 1 2 2 2 0 Transcriptional regulator, SIX1, N-terminal SD domain Complex1_49kDa PF00346.19 KSA03835.1 - 1.1e-119 398.6 0.0 1.4e-119 398.2 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 KSA03835.1 - 0.0054 15.7 0.0 0.0089 15.0 0.0 1.3 1 0 0 1 1 1 1 Nickel-dependent hydrogenase DnaJ PF00226.31 KSA03836.1 - 1.2e-17 63.7 5.3 2.5e-17 62.7 5.3 1.6 1 0 0 1 1 1 1 DnaJ domain Cnd1 PF12717.7 KSA03836.1 - 0.096 12.7 0.6 11 6.1 0.1 2.1 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 DUF148 PF02520.17 KSA03836.1 - 0.22 11.7 2.3 1.5 9.0 0.1 2.5 2 1 0 2 2 2 0 Domain of unknown function DUF148 DUF2076 PF09849.9 KSA03837.1 - 0.00016 21.8 17.5 0.00016 21.8 17.5 1.5 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.13 KSA03837.1 - 0.00038 20.5 5.7 0.00038 20.5 5.7 1.6 2 0 0 2 2 2 1 CHCH domain MTCP1 PF08991.10 KSA03837.1 - 0.044 14.0 4.5 0.084 13.1 4.5 1.4 1 0 0 1 1 1 0 Mature-T-Cell Proliferation I type CX9C PF16860.5 KSA03837.1 - 0.071 13.1 6.4 0.13 12.3 6.4 1.5 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Nucleoporin_FG PF13634.6 KSA03837.1 - 1.8 9.5 13.0 4.2 8.3 13.0 1.7 1 1 0 1 1 1 0 Nucleoporin FG repeat region Sec-ASP3 PF15432.6 KSA03838.1 - 0.00087 19.4 0.1 0.0016 18.6 0.1 1.4 1 0 0 1 1 1 1 Accessory Sec secretory system ASP3 Insulin_TMD PF17870.1 KSA03839.1 - 0.0015 18.6 0.8 0.0034 17.4 0.8 1.6 1 0 0 1 1 1 1 Insulin receptor trans-membrane segment DAO PF01266.24 KSA03840.1 - 1e-30 107.5 0.0 1.4e-30 107.1 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase ApbA PF02558.16 KSA03840.1 - 0.059 13.0 0.2 0.45 10.2 0.1 2.2 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_binding_8 PF13450.6 KSA03840.1 - 0.059 13.6 0.1 0.19 12.0 0.0 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KSA03840.1 - 0.09 12.8 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 FAD-NAD(P)-binding Sacchrp_dh_NADP PF03435.18 KSA03840.1 - 0.18 12.0 0.0 0.29 11.4 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Fungal_trans_2 PF11951.8 KSA03841.1 - 1.4e-62 211.7 0.6 1.7e-62 211.5 0.6 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain G-alpha PF00503.20 KSA03841.1 - 0.04 13.1 0.1 0.069 12.3 0.1 1.4 1 0 0 1 1 1 0 G-protein alpha subunit AA_permease PF00324.21 KSA03842.1 - 9.4e-88 294.9 46.8 1.1e-87 294.6 46.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KSA03842.1 - 7.5e-19 67.9 50.6 7.5e-19 67.9 50.6 1.5 1 1 0 1 1 1 1 Amino acid permease Peptidase_M19 PF01244.21 KSA03843.1 - 2.8e-107 358.6 0.0 3.3e-107 358.3 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Topoisom_I_N PF02919.15 KSA03844.1 - 7e-97 323.1 1.1 7e-97 323.1 1.1 3.4 4 1 1 5 5 5 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.20 KSA03844.1 - 6.6e-93 310.2 0.8 6.6e-93 310.2 0.8 2.1 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.6 KSA03844.1 - 5.6e-31 106.3 1.5 1.9e-30 104.6 1.5 2.0 1 0 0 1 1 1 1 C-terminal topoisomerase domain Pkinase PF00069.25 KSA03845.1 - 2.1e-72 243.6 0.0 3.5e-72 242.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KSA03845.1 - 5.1e-37 127.5 0.0 9e-37 126.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 KSA03845.1 - 5e-25 87.5 0.1 2.7e-13 49.9 0.0 2.9 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.6 KSA03845.1 - 1.4e-09 37.7 0.0 1.3e-08 34.6 0.0 2.0 1 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 KSA03845.1 - 0.0064 15.9 0.0 0.015 14.7 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KSA03845.1 - 0.034 14.1 0.0 0.05 13.5 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family RNA_pol_L_2 PF13656.6 KSA03846.1 - 2.8e-26 91.1 0.0 4e-26 90.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 KSA03846.1 - 9e-08 31.4 0.0 1.5e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Abhydrolase_6 PF12697.7 KSA03847.1 - 7.6e-16 59.4 0.0 1e-15 58.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KSA03847.1 - 1.5e-09 37.4 0.0 2.6e-08 33.5 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KSA03847.1 - 8.6e-07 28.8 0.4 1.8e-06 27.8 0.4 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 KSA03847.1 - 1.2e-05 25.2 0.0 2.2e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Putative esterase FSH1 PF03959.13 KSA03847.1 - 0.0011 18.7 0.1 0.5 10.0 0.0 2.4 2 0 0 2 2 2 2 Serine hydrolase (FSH1) Peptidase_S9 PF00326.21 KSA03847.1 - 0.0015 18.1 0.0 0.0038 16.7 0.0 1.7 1 0 0 1 1 1 1 Prolyl oligopeptidase family LIDHydrolase PF10230.9 KSA03847.1 - 0.011 15.3 0.1 0.016 14.8 0.1 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Abhydrolase_2 PF02230.16 KSA03847.1 - 0.06 13.1 0.1 1.1 9.1 0.0 2.3 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Toprim_2 PF13155.6 KSA03847.1 - 0.13 12.7 0.0 2.6 8.5 0.0 2.5 2 0 0 2 2 2 0 Toprim-like HA2 PF04408.23 KSA03848.1 - 4e-22 78.6 0.3 1.9e-21 76.3 0.0 2.5 2 0 0 2 2 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KSA03848.1 - 1.1e-21 77.0 0.0 3.2e-21 75.5 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KSA03848.1 - 1.1e-14 54.7 0.1 1.3e-13 51.3 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 KSA03848.1 - 5.5e-08 32.8 0.9 2.1e-07 30.9 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KSA03848.1 - 1.5e-07 31.8 0.3 1.3e-06 28.8 0.0 2.6 2 1 1 3 3 3 1 AAA domain T2SSE PF00437.20 KSA03848.1 - 0.00064 18.9 0.0 0.0011 18.1 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.6 KSA03848.1 - 0.0055 17.0 0.0 0.018 15.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KSA03848.1 - 0.0057 16.4 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 KSA03848.1 - 0.051 13.2 0.1 0.23 11.1 0.0 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain PhoH PF02562.16 KSA03848.1 - 0.059 12.8 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_17 PF13207.6 KSA03848.1 - 0.15 12.5 0.6 14 6.1 0.1 3.3 2 1 0 2 2 2 0 AAA domain PRK PF00485.18 KSA03849.1 - 2.7e-61 206.8 0.0 4.7e-61 206.0 0.0 1.4 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.6 KSA03849.1 - 4.4e-36 124.3 0.0 6.7e-36 123.7 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase KAP_NTPase PF07693.14 KSA03849.1 - 0.00014 21.2 0.0 0.00024 20.4 0.0 1.7 1 1 0 1 1 1 1 KAP family P-loop domain AAA_18 PF13238.6 KSA03849.1 - 0.00051 20.6 0.0 0.0011 19.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain CPT PF07931.12 KSA03849.1 - 0.00069 19.5 0.0 0.0013 18.6 0.0 1.4 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein Zeta_toxin PF06414.12 KSA03849.1 - 0.0022 17.3 0.0 0.004 16.5 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin NACHT PF05729.12 KSA03849.1 - 0.014 15.4 0.0 0.027 14.4 0.0 1.5 1 0 0 1 1 1 0 NACHT domain MobB PF03205.14 KSA03849.1 - 0.014 15.3 0.0 0.029 14.3 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.6 KSA03849.1 - 0.018 15.2 0.0 0.033 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KSA03849.1 - 0.04 13.1 0.0 0.072 12.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.6 KSA03849.1 - 0.047 14.1 0.0 0.086 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_17 PF13207.6 KSA03849.1 - 0.084 13.3 0.1 0.71 10.3 0.1 2.5 2 1 0 2 2 2 0 AAA domain DXPR_C PF13288.6 KSA03849.1 - 0.12 12.6 0.2 1.2 9.5 0.1 2.3 2 0 0 2 2 2 0 DXP reductoisomerase C-terminal domain ABC_tran PF00005.27 KSA03849.1 - 0.13 12.8 0.0 0.27 11.8 0.0 1.5 1 0 0 1 1 1 0 ABC transporter DUF4667 PF15700.5 KSA03850.1 - 9.7e-05 22.6 7.5 0.00068 19.8 2.1 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF4667) Aminotran_1_2 PF00155.21 KSA03851.1 - 5.4e-41 141.0 0.0 1.3e-40 139.8 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KSA03851.1 - 0.0088 15.4 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Gaa1 PF04114.14 KSA03852.1 - 1e-133 447.0 14.1 1.2e-133 446.8 14.1 1.1 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component GEP5 PF17053.5 KSA03853.1 - 1.6e-31 109.9 6.3 2.7e-31 109.2 6.3 1.3 1 0 0 1 1 1 1 Genetic interactor of prohibitin 5 Complex1_LYR PF05347.15 KSA03853.1 - 0.00035 20.6 0.5 0.00035 20.6 0.5 2.2 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KSA03853.1 - 2.3 9.0 6.0 11 6.9 0.9 2.8 3 0 0 3 3 3 0 Complex1_LYR-like ANAPC4 PF12896.7 KSA03854.1 - 8.6e-64 214.8 5.4 1.5e-63 214.0 5.4 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 ANAPC4_WD40 PF12894.7 KSA03854.1 - 3e-24 85.1 0.2 5.7e-24 84.2 0.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KSA03854.1 - 0.00097 19.1 0.4 0.0019 18.1 0.4 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 KSA03854.1 - 0.0045 17.8 0.2 0.062 14.2 0.1 2.8 2 0 0 2 2 2 1 WD domain, G-beta repeat LAGLIDADG_1 PF00961.19 KSA03854.1 - 0.016 16.1 6.2 0.016 16.1 6.2 3.9 4 1 1 5 5 5 0 LAGLIDADG endonuclease DUF565 PF04483.12 KSA03854.1 - 0.097 13.2 0.2 0.35 11.4 0.2 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF565) Ribosomal_L1 PF00687.21 KSA03855.1 - 7.8e-23 81.3 0.2 1.1e-22 80.7 0.2 1.3 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family RhoGAP PF00620.27 KSA03856.1 - 2.1e-17 63.4 0.3 6.4e-17 61.8 0.1 1.9 1 1 0 1 1 1 1 RhoGAP domain cNMP_binding PF00027.29 KSA03857.1 - 1.4e-24 86.0 0.0 3.7e-15 55.8 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain LRR_6 PF13516.6 KSA03857.1 - 3.3e-08 33.0 21.8 0.42 10.8 0.0 8.7 11 0 0 11 11 11 4 Leucine Rich repeat LRR_4 PF12799.7 KSA03857.1 - 3.3e-07 30.5 13.6 0.0016 18.8 0.2 6.1 5 1 2 7 7 7 2 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KSA03857.1 - 1.4e-05 24.9 0.0 4.8e-05 23.2 0.0 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KSA03857.1 - 9e-05 22.3 2.9 0.001 18.9 0.0 3.7 4 0 0 4 4 4 1 F-box domain LRR_1 PF00560.33 KSA03857.1 - 0.0057 17.0 13.9 7.3 7.6 0.7 8.2 8 1 0 8 8 8 1 Leucine Rich Repeat Dimerisation2 PF16864.5 KSA03857.1 - 0.14 12.1 0.0 10 6.2 0.0 2.6 2 0 0 2 2 2 0 Dimerisation domain LRR_8 PF13855.6 KSA03857.1 - 0.82 9.5 4.0 1.2 8.9 0.2 3.4 3 1 0 3 3 3 0 Leucine rich repeat SUI1 PF01253.22 KSA03858.1 - 3.9e-18 65.8 0.1 1.7e-16 60.5 0.0 2.6 2 0 0 2 2 2 1 Translation initiation factor SUI1 Pre-PUA PF17832.1 KSA03858.1 - 2.4e-15 57.0 0.6 1.1e-14 54.9 0.6 2.2 1 0 0 1 1 1 1 Pre-PUA-like domain SWIB PF02201.18 KSA03858.1 - 0.00022 21.0 0.2 0.00074 19.4 0.2 1.9 1 0 0 1 1 1 1 SWIB/MDM2 domain IL2 PF00715.17 KSA03858.1 - 0.1 12.6 1.2 18 5.2 0.2 2.8 3 0 0 3 3 3 0 Interleukin 2 PUA PF01472.20 KSA03858.1 - 0.11 12.5 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 PUA domain PIG-S PF10510.9 KSA03859.1 - 1.7e-117 393.4 5.1 2e-117 393.2 5.1 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein Endonuclease_NS PF01223.23 KSA03860.1 - 6.8e-63 212.5 0.0 8e-63 212.3 0.0 1.0 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease DUF1729 PF08354.10 KSA03861.1 - 6.1e-152 505.6 0.0 9.4e-152 505.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Acyl_transf_1 PF00698.21 KSA03861.1 - 4.6e-90 302.4 0.0 1.8e-88 297.1 0.0 3.1 4 0 0 4 4 4 1 Acyl transferase domain FAS_meander PF17951.1 KSA03861.1 - 1.5e-48 164.3 0.0 3.2e-48 163.2 0.0 1.6 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain SAT PF16073.5 KSA03861.1 - 3.6e-39 134.9 0.0 6.3e-39 134.1 0.0 1.4 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis MaoC_dehydratas PF01575.19 KSA03861.1 - 1.7e-38 131.0 0.1 3.3e-38 130.0 0.1 1.4 1 0 0 1 1 1 1 MaoC like domain FAS_N PF17828.1 KSA03861.1 - 1e-32 112.8 0.0 2.8e-32 111.5 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta MaoC_dehydrat_N PF13452.6 KSA03861.1 - 2.2e-13 50.5 0.0 7e-13 48.9 0.0 1.9 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase SinI PF08671.10 KSA03861.1 - 0.1 12.4 0.1 3.2 7.6 0.0 2.9 2 0 0 2 2 2 0 Anti-repressor SinI His_Phos_2 PF00328.22 KSA03862.1 - 1.3e-145 485.5 0.3 1.7e-145 485.2 0.3 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 KSA03862.1 - 5.1e-36 122.7 0.0 1.5e-35 121.2 0.0 1.9 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 KSA03862.1 - 1.4e-05 24.8 0.0 3e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Pribosyltran_N PF13793.6 KSA03863.1 - 8.9e-40 135.3 0.0 2e-39 134.1 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 KSA03863.1 - 2.2e-39 135.4 1.5 5.1e-31 108.1 0.2 2.3 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 KSA03863.1 - 7.1e-07 28.9 0.2 0.0031 17.0 0.1 2.4 2 0 0 2 2 2 2 Phosphoribosyl transferase domain SRR1 PF07985.12 KSA03864.1 - 2.5e-18 65.8 0.1 5.5e-18 64.8 0.1 1.6 1 0 0 1 1 1 1 SRR1 HSF_DNA-bind PF00447.17 KSA03865.1 - 4.8e-30 104.0 5.3 9.8e-30 103.0 5.3 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.24 KSA03865.1 - 1.6e-26 92.6 0.3 5.2e-26 91.0 0.3 1.9 2 0 0 2 2 2 1 Response regulator receiver domain Tox-HDC PF15656.6 KSA03865.1 - 0.011 16.0 0.2 0.045 13.9 0.1 2.0 2 0 0 2 2 2 0 Toxin with a H, D/N and C signature KASH_CCD PF14662.6 KSA03865.1 - 0.013 15.3 0.5 0.021 14.7 0.5 1.3 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH HALZ PF02183.18 KSA03865.1 - 0.029 14.6 1.4 0.061 13.6 1.4 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper Ets PF00178.22 KSA03865.1 - 0.079 13.4 0.2 0.079 13.4 0.2 1.7 2 0 0 2 2 2 0 Ets-domain Spermine_synth PF01564.17 KSA03865.1 - 0.092 12.1 0.7 0.19 11.1 0.1 1.7 2 0 0 2 2 2 0 Spermine/spermidine synthase domain ATG16 PF08614.11 KSA03865.1 - 0.19 12.0 0.1 0.19 12.0 0.1 2.5 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) ZapB PF06005.12 KSA03865.1 - 0.33 11.4 2.3 1.7 9.1 2.3 2.2 1 1 0 1 1 1 0 Cell division protein ZapB Glyco_hydro_31 PF01055.26 KSA03866.1 - 1.8e-128 429.5 5.4 2.7e-128 428.9 5.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KSA03866.1 - 2.3e-25 88.7 0.6 1.3e-23 83.0 0.3 2.8 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 KSA03866.1 - 9.4e-08 32.2 3.2 5.9e-07 29.7 0.6 3.0 2 0 0 2 2 2 1 Domain of unknown function (DUF5110) BRE1 PF08647.11 KSA03867.1 - 2.2e-23 82.2 13.4 2.2e-23 82.2 13.4 7.5 4 1 3 7 7 4 1 BRE1 E3 ubiquitin ligase zf-C3HC4_3 PF13920.6 KSA03867.1 - 1.5e-07 31.1 5.9 2.5e-07 30.4 5.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KSA03867.1 - 2.4e-07 30.5 5.1 4.2e-07 29.7 5.1 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KSA03867.1 - 2.7e-07 30.3 7.2 5.2e-07 29.4 7.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KSA03867.1 - 7e-06 25.9 8.2 1.2e-05 25.1 8.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KSA03867.1 - 8.5e-06 25.5 6.7 1.7e-05 24.6 6.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KSA03867.1 - 3.5e-05 24.0 7.5 6.1e-05 23.3 7.5 1.4 1 0 0 1 1 1 1 Ring finger domain JIP_LZII PF16471.5 KSA03867.1 - 0.00013 22.1 3.6 0.00013 22.1 3.6 9.5 4 2 5 10 10 9 2 JNK-interacting protein leucine zipper II zf-RING_UBOX PF13445.6 KSA03867.1 - 0.0021 18.1 6.4 0.005 16.8 6.4 1.7 1 0 0 1 1 1 1 RING-type zinc-finger ATG16 PF08614.11 KSA03867.1 - 0.0075 16.5 14.9 0.0075 16.5 14.9 4.6 3 1 2 5 5 5 1 Autophagy protein 16 (ATG16) zf-C3HC4_4 PF15227.6 KSA03867.1 - 0.012 15.8 5.2 0.025 14.8 5.2 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 KSA03867.1 - 0.018 15.3 5.1 0.044 14.1 5.1 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain DUF1192 PF06698.11 KSA03867.1 - 0.031 14.3 4.0 0.34 11.0 1.5 3.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) zf-C2H2 PF00096.26 KSA03867.1 - 0.096 13.2 2.8 0.13 12.8 0.1 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type HypA PF01155.19 KSA03867.1 - 0.19 11.8 6.6 1.8 8.6 6.6 2.7 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Gin PF10764.9 KSA03867.1 - 0.3 11.1 1.9 0.82 9.7 1.9 1.7 1 0 0 1 1 1 0 Inhibitor of sigma-G Gin zf-RING_10 PF16685.5 KSA03867.1 - 0.33 11.1 4.4 1.2 9.3 4.4 2.1 1 0 0 1 1 1 0 zinc RING finger of MSL2 DUF1272 PF06906.11 KSA03867.1 - 0.58 10.3 4.2 1.2 9.2 4.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-RING_4 PF14570.6 KSA03867.1 - 0.9 9.4 5.4 1.8 8.4 5.4 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C2H2_4 PF13894.6 KSA03867.1 - 2 9.5 5.1 6.1 8.0 0.1 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger Bromodomain PF00439.25 KSA03868.1 - 1.7e-38 130.5 2.7 1.4e-19 69.9 0.2 2.6 2 0 0 2 2 2 2 Bromodomain BET PF17035.5 KSA03868.1 - 5.8e-16 58.4 2.8 1.9e-15 56.7 2.8 2.0 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation DUF4441 PF14536.6 KSA03868.1 - 0.051 13.8 0.1 0.051 13.8 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4441) CsgA PF17334.2 KSA03868.1 - 3.9 8.3 6.7 16 6.3 0.3 3.8 4 0 0 4 4 4 0 Minor curli fiber component A Dus PF01207.17 KSA03869.1 - 2.5e-74 250.2 0.0 3.1e-74 249.9 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.21 KSA03869.1 - 0.00041 19.7 0.3 0.0022 17.3 0.3 1.8 1 1 1 2 2 2 1 Dihydroorotate dehydrogenase TMP-TENI PF02581.17 KSA03869.1 - 0.0021 17.4 0.1 0.0036 16.7 0.1 1.3 1 0 0 1 1 1 1 Thiamine monophosphate synthase Oxidored_FMN PF00724.20 KSA03869.1 - 0.018 14.4 0.1 0.026 13.8 0.1 1.2 1 0 0 1 1 1 0 NADH:flavin oxidoreductase / NADH oxidase family Resolvase PF00239.21 KSA03869.1 - 0.054 13.6 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 Resolvase, N terminal domain RMMBL PF07521.12 KSA03869.1 - 0.17 11.9 0.0 0.55 10.2 0.0 1.8 2 0 0 2 2 2 0 Zn-dependent metallo-hydrolase RNA specificity domain SMC_N PF02463.19 KSA03870.1 - 6.2e-61 205.6 66.2 1.3e-59 201.3 66.2 3.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KSA03870.1 - 1.4e-21 76.9 0.0 5.2e-21 75.1 0.0 2.1 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KSA03870.1 - 3.1e-09 37.1 19.5 3.9e-06 26.9 0.2 3.9 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KSA03870.1 - 1.1e-06 28.6 18.4 1.1e-06 28.6 18.4 5.0 3 2 2 5 5 5 1 AAA ATPase domain AAA_29 PF13555.6 KSA03870.1 - 0.00013 21.7 0.0 0.00029 20.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain PI3K_P85_iSH2 PF16454.5 KSA03870.1 - 0.0049 16.5 10.6 0.0049 16.5 10.6 7.8 2 2 6 8 8 8 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain MtrB PF05440.12 KSA03870.1 - 0.41 11.1 4.4 1.6 9.2 0.1 4.2 4 0 0 4 4 4 0 Tetrahydromethanopterin S-methyltransferase subunit B AAA_13 PF13166.6 KSA03870.1 - 3 6.4 118.8 0.041 12.5 6.6 5.3 2 2 3 5 5 5 0 AAA domain RNA_polI_A14 PF08203.11 KSA03871.1 - 7.7e-25 87.4 0.1 7.7e-25 87.4 0.1 2.4 2 1 0 2 2 2 1 Yeast RNA polymerase I subunit RPA14 CDC45 PF02724.14 KSA03871.1 - 0.072 11.4 20.8 0.087 11.1 20.8 1.1 1 0 0 1 1 1 0 CDC45-like protein RNA_polI_A34 PF08208.11 KSA03871.1 - 0.14 12.2 41.1 0.23 11.5 41.1 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 GAGA_bind PF06217.12 KSA03871.1 - 0.16 12.2 12.7 0.19 12.0 12.7 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family RR_TM4-6 PF06459.12 KSA03871.1 - 0.18 11.6 20.8 0.25 11.1 20.8 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SelP_N PF04592.14 KSA03871.1 - 7.5 5.9 15.8 11 5.3 15.8 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Ribosomal_L34 PF00468.17 KSA03872.1 - 2.3e-22 78.7 6.9 2.7e-22 78.4 6.1 1.5 1 1 0 1 1 1 1 Ribosomal protein L34 CHDNT PF08073.12 KSA03873.1 - 0.031 14.2 0.1 0.087 12.8 0.1 1.7 1 0 0 1 1 1 0 CHDNT (NUC034) domain UCMA PF17085.5 KSA03874.1 - 0.37 10.8 7.1 1.2 9.2 2.0 2.9 2 0 0 2 2 2 0 Unique cartilage matrix associated protein DnaJ_C PF01556.18 KSA03876.1 - 4.9e-33 114.3 0.5 7.9e-33 113.6 0.5 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KSA03876.1 - 6.5e-24 83.8 3.7 1.2e-23 83.0 3.7 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KSA03876.1 - 1.6e-13 50.8 16.2 2.8e-13 50.0 16.2 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KSA03876.1 - 0.0058 16.6 7.6 0.64 10.0 0.2 2.5 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 KSA03876.1 - 0.3 11.1 4.8 5.2 7.1 0.3 2.5 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF1356 PF07092.12 KSA03876.1 - 0.49 9.6 2.9 1.8 7.8 0.1 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1356) Cytochrom_c3_2 PF14537.6 KSA03876.1 - 1.2 9.7 7.9 4.2 7.9 7.9 1.9 1 1 1 2 2 2 0 Cytochrome c3 HTH_Tnp_Tc5 PF03221.16 KSA03877.1 - 9.3e-13 48.0 0.3 9.3e-13 48.0 0.3 2.3 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain DUF4776 PF16003.5 KSA03877.1 - 2.2 7.2 31.5 2.7 6.9 1.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4776) Rotamase_2 PF13145.6 KSA03877.1 - 8.3 7.3 18.1 4.8 8.0 13.2 2.6 2 0 0 2 2 2 0 PPIC-type PPIASE domain ApbA_C PF08546.11 KSA03878.1 - 1.9e-28 99.2 0.0 4.3e-28 98.0 0.1 1.6 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 KSA03878.1 - 2.3e-12 46.8 0.0 3.6e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA GvpG PF05120.12 KSA03880.1 - 0.76 9.8 3.7 2.6 8.1 3.7 1.9 1 0 0 1 1 1 0 Gas vesicle protein G DUF4407 PF14362.6 KSA03880.1 - 1.1 8.6 7.8 0.22 10.8 4.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Allantoicase PF03561.15 KSA03881.1 - 3.9e-92 305.8 0.1 2.5e-47 160.5 0.0 2.0 2 0 0 2 2 2 2 Allantoicase repeat F5_F8_type_C PF00754.25 KSA03881.1 - 0.14 12.3 0.0 0.36 10.9 0.0 1.8 1 0 0 1 1 1 0 F5/8 type C domain Methyltransf_16 PF10294.9 KSA03882.1 - 7.5e-25 87.7 0.0 1.2e-24 86.9 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 KSA03882.1 - 0.0029 17.2 0.0 0.0045 16.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 KSA03882.1 - 0.0032 17.3 0.0 0.005 16.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KSA03882.1 - 0.0047 16.7 0.0 0.0087 15.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FAM86 PF14904.6 KSA03882.1 - 0.0057 16.7 0.1 0.011 15.8 0.1 1.5 1 0 0 1 1 1 1 Family of unknown function Methyltransf_25 PF13649.6 KSA03882.1 - 0.037 14.7 0.0 0.069 13.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 KSA03882.1 - 0.088 13.6 0.0 0.18 12.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Csm1_B PF18211.1 KSA03882.1 - 0.13 12.1 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 Csm1 subunit domain B ATP-synt_J PF04911.12 KSA03883.1 - 7.3e-27 92.7 0.6 8.1e-27 92.6 0.6 1.0 1 0 0 1 1 1 1 ATP synthase j chain ENTH PF01417.20 KSA03884.1 - 2.3e-45 153.6 0.3 3.8e-45 153.0 0.3 1.4 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 KSA03884.1 - 6.5e-05 22.0 0.0 0.00013 21.1 0.0 1.4 1 0 0 1 1 1 1 ANTH domain DSS1_SEM1 PF05160.13 KSA03884.1 - 0.00083 19.4 0.5 2.7 8.1 0.1 3.5 3 0 0 3 3 3 1 DSS1/SEM1 family VHS PF00790.19 KSA03884.1 - 0.033 14.0 0.1 0.057 13.3 0.1 1.4 1 0 0 1 1 1 0 VHS domain Pro_isomerase PF00160.21 KSA03885.1 - 1.2e-48 165.4 0.0 1.4e-48 165.1 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-C2H2_jaz PF12171.8 KSA03887.1 - 0.00084 19.6 0.0 0.0021 18.3 0.0 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KSA03887.1 - 0.0072 16.7 0.0 0.014 15.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 KSA03887.1 - 0.033 14.7 0.1 0.087 13.3 0.1 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type SNRNP27 PF08648.12 KSA03887.1 - 0.036 14.1 0.4 0.036 14.1 0.4 2.7 2 0 0 2 2 2 0 U4/U6.U5 small nuclear ribonucleoproteins Pinin_SDK_memA PF04696.13 KSA03887.1 - 0.23 11.5 13.0 0.53 10.4 13.0 1.5 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region TPX2 PF06886.11 KSA03887.1 - 0.66 10.3 14.9 0.62 10.3 12.3 2.1 2 0 0 2 2 2 0 Targeting protein for Xklp2 (TPX2) Draxin PF15550.6 KSA03887.1 - 1.1 9.0 9.3 0.075 12.9 3.5 1.7 2 0 0 2 2 2 0 Draxin Glyco_hydro_3_C PF01915.22 KSA03888.1 - 1.4e-59 201.5 0.0 2.6e-59 200.6 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KSA03888.1 - 4.8e-47 160.9 0.0 7.6e-47 160.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KSA03888.1 - 2.3e-24 85.3 0.3 5.2e-24 84.1 0.3 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 KSA03888.1 - 3.1e-21 75.7 0.1 5.8e-21 74.8 0.1 1.4 1 0 0 1 1 1 1 PA14 domain GLEYA PF10528.9 KSA03888.1 - 0.005 17.2 0.0 0.021 15.2 0.0 2.1 1 0 0 1 1 1 1 GLEYA domain Macro_2 PF14519.6 KSA03888.1 - 0.0096 15.3 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 1 Macro-like domain Phage_tail_X PF05489.12 KSA03888.1 - 0.014 15.0 0.0 0.043 13.5 0.0 1.7 1 0 0 1 1 1 0 Phage Tail Protein X CARDB PF07705.11 KSA03888.1 - 0.08 13.2 0.2 0.24 11.7 0.1 1.9 2 0 0 2 2 2 0 CARDB PNK3P PF08645.11 KSA03889.1 - 2.8e-52 176.7 1.4 4.1e-52 176.1 1.4 1.2 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase HAD PF12710.7 KSA03889.1 - 0.01 16.2 0.1 0.082 13.3 0.1 2.2 1 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KSA03889.1 - 0.04 14.0 1.3 1.5 8.8 0.1 3.0 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase Peptidase_U32_C PF16325.5 KSA03889.1 - 0.043 14.1 0.1 2.1 8.7 0.0 2.6 2 0 0 2 2 2 0 Peptidase family U32 C-terminal domain Cadherin PF00028.17 KSA03889.1 - 0.097 13.1 0.2 3.6 8.1 0.1 2.4 1 1 1 2 2 2 0 Cadherin domain ADK PF00406.22 KSA03890.1 - 0.0053 16.9 0.3 0.0083 16.2 0.3 1.4 1 0 0 1 1 1 1 Adenylate kinase BRCA-2_helical PF09169.10 KSA03890.1 - 0.043 13.5 0.0 0.072 12.8 0.0 1.3 1 0 0 1 1 1 0 BRCA2, helical Ribosomal_S8 PF00410.19 KSA03891.1 - 1.9e-12 47.3 0.0 1.5e-11 44.3 0.0 1.9 1 1 0 1 1 1 1 Ribosomal protein S8 Pox_A_type_inc PF04508.12 KSA03892.1 - 0.012 15.4 0.1 0.086 12.7 0.1 2.5 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat TMEM192 PF14802.6 KSA03892.1 - 9 5.3 8.6 0.09 11.9 0.7 1.7 2 0 0 2 2 2 0 TMEM192 family MFS_1 PF07690.16 KSA03893.1 - 1.7e-30 106.1 45.3 1.4e-20 73.6 16.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KSA03893.1 - 0.0019 17.2 20.2 0.0019 17.2 20.2 2.6 1 1 0 2 2 2 2 Sugar (and other) transporter Myc_target_1 PF15179.6 KSA03893.1 - 0.041 13.8 1.1 0.11 12.4 1.1 1.7 1 0 0 1 1 1 0 Myc target protein 1 TssO PF17561.2 KSA03893.1 - 3 7.9 4.6 31 4.7 0.8 2.8 2 0 0 2 2 2 0 Type VI secretion system, TssO Zip PF02535.22 KSA03894.1 - 3.1e-72 243.6 2.2 3.5e-72 243.4 2.2 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter ArAE_2_N PF10337.9 KSA03894.1 - 0.071 12.1 0.8 0.78 8.7 0.2 2.2 2 0 0 2 2 2 0 Putative ER transporter, 6TM, N-terminal CBS PF00571.28 KSA03895.1 - 1.5e-26 92.6 7.2 6.3e-11 42.5 0.3 4.4 4 0 0 4 4 4 4 CBS domain OPT PF03169.15 KSA03896.1 - 2.9e-145 485.4 22.8 3.3e-145 485.2 22.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4181 PF13789.6 KSA03896.1 - 3.9 7.8 7.6 4.2 7.7 0.4 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4181) KH_1 PF00013.29 KSA03897.1 - 3.4e-39 132.5 5.4 3.1e-12 46.1 0.7 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KSA03897.1 - 2.3e-09 37.0 3.9 0.0014 18.4 0.1 3.5 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 KSA03897.1 - 7.4e-05 22.5 0.0 0.13 12.1 0.0 3.4 3 0 0 3 3 3 2 KH domain KH_5 PF13184.6 KSA03897.1 - 0.00056 19.9 3.2 2.8 8.1 0.1 3.4 3 0 0 3 3 3 2 NusA-like KH domain BCNT PF07572.12 KSA03898.1 - 3.5e-25 87.9 4.3 1.4e-24 86.0 4.3 2.1 1 0 0 1 1 1 1 Bucentaur or craniofacial development Peptidase_M49 PF03571.15 KSA03899.1 - 9.7e-231 766.9 0.1 1.8e-230 766.1 0.0 1.4 2 0 0 2 2 2 1 Peptidase family M49 DUF3873 PF12989.7 KSA03899.1 - 0.11 12.9 0.0 0.32 11.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3873) ERp29 PF07749.12 KSA03899.1 - 0.13 13.2 3.8 4.5 8.2 0.1 4.1 4 0 0 4 4 4 0 Endoplasmic reticulum protein ERp29, C-terminal domain DUF745 PF05335.13 KSA03899.1 - 0.27 10.9 1.4 0.46 10.2 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF745) ABC_membrane PF00664.23 KSA03900.1 - 3.4e-47 161.4 5.8 4.9e-47 160.9 5.8 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KSA03900.1 - 1.2e-29 103.5 0.3 8.8e-29 100.8 0.0 2.2 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 KSA03900.1 - 1.2e-06 28.2 0.0 7.2e-06 25.6 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA PF00004.29 KSA03900.1 - 2.9e-05 24.5 0.1 0.0014 19.0 0.1 2.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ABC_ATPase PF09818.9 KSA03900.1 - 4.7e-05 22.4 0.2 8e-05 21.6 0.2 1.3 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_22 PF13401.6 KSA03900.1 - 0.0027 18.0 0.1 0.045 14.0 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 KSA03900.1 - 0.019 14.6 0.0 0.052 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KSA03900.1 - 0.023 15.1 0.3 0.14 12.6 0.0 2.4 1 1 0 2 2 2 0 AAA ATPase domain DUF2073 PF09846.9 KSA03900.1 - 0.028 14.3 0.2 0.094 12.6 0.1 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2073) DEAD PF00270.29 KSA03900.1 - 0.054 13.2 0.0 1.6 8.4 0.0 2.4 2 0 0 2 2 2 0 DEAD/DEAH box helicase CdiI_3 PF18616.1 KSA03900.1 - 0.11 12.4 0.2 28 4.7 0.0 3.1 2 1 1 3 3 3 0 CDI immunity proteins IFT20 PF14931.6 KSA03900.1 - 0.49 10.6 4.8 0.29 11.3 0.3 2.6 2 1 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 DUF87 PF01935.17 KSA03900.1 - 4.7 7.2 9.5 8.9 6.3 0.0 3.1 4 0 0 4 4 4 0 Helicase HerA, central domain ATP-synt_Eps PF04627.13 KSA03901.1 - 9.7e-18 63.9 0.3 1.1e-17 63.7 0.3 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain T2SSF PF00482.23 KSA03901.1 - 0.09 12.7 0.1 0.11 12.5 0.1 1.2 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F DNA_pol_phi PF04931.13 KSA03902.1 - 1.3e-65 221.9 36.6 1.3e-65 221.9 36.6 2.0 2 0 0 2 2 2 1 DNA polymerase phi Syntaxin_2 PF14523.6 KSA03902.1 - 0.0074 16.6 0.1 0.0074 16.6 0.1 3.2 3 1 0 3 3 3 1 Syntaxin-like protein BUD22 PF09073.10 KSA03902.1 - 1.5 8.1 26.3 0.82 8.9 20.7 2.4 2 0 0 2 2 2 0 BUD22 ParB PF08775.10 KSA03902.1 - 3.1 8.3 9.7 0.16 12.5 0.8 3.1 3 0 0 3 3 3 0 ParB family DNA_pol_phi PF04931.13 KSA03903.1 - 7.2e-110 368.3 19.7 8.2e-110 368.1 19.7 1.0 1 0 0 1 1 1 1 DNA polymerase phi MMS22L_C PF14911.6 KSA03903.1 - 0.00036 19.7 0.8 0.00036 19.7 0.8 1.8 2 1 0 2 2 2 1 S-phase genomic integrity recombination mediator, C-terminal IFRD PF05004.13 KSA03903.1 - 3.2 6.8 10.8 0.045 12.8 1.9 2.2 2 1 0 2 2 2 0 Interferon-related developmental regulator (IFRD) PfkB PF00294.24 KSA03904.1 - 1.2e-72 244.8 0.6 1.3e-72 244.6 0.6 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 KSA03904.1 - 3.8e-06 26.5 0.0 8.5e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase DUF3876 PF12992.7 KSA03904.1 - 0.16 12.1 0.5 0.44 10.7 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF3876) TRAM_LAG1_CLN8 PF03798.16 KSA03905.1 - 8.5e-35 120.3 21.6 1.3e-34 119.7 21.6 1.2 1 0 0 1 1 1 1 TLC domain Ras PF00071.22 KSA03906.1 - 1.4e-64 216.6 0.2 1.7e-64 216.3 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KSA03906.1 - 1e-36 125.8 0.1 1.9e-36 124.9 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KSA03906.1 - 5e-17 61.9 0.1 6.3e-17 61.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KSA03906.1 - 2.1e-06 27.2 0.0 2.5e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KSA03906.1 - 7e-05 22.8 0.4 0.16 11.9 0.0 2.4 1 1 1 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KSA03906.1 - 0.00022 21.3 0.0 0.00022 21.3 0.0 1.6 2 0 0 2 2 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KSA03906.1 - 0.00022 20.8 0.1 0.00073 19.1 0.1 1.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KSA03906.1 - 0.00055 19.4 0.0 0.00087 18.8 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA PF00004.29 KSA03906.1 - 0.0057 17.1 0.0 0.11 12.9 0.0 2.2 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KSA03906.1 - 0.011 16.2 0.0 0.017 15.5 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.9 KSA03906.1 - 0.033 13.9 0.0 1.4 8.7 0.0 2.4 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.6 KSA03906.1 - 0.038 13.7 0.1 0.15 11.8 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_22 PF13401.6 KSA03906.1 - 0.053 13.8 0.1 0.15 12.4 0.1 2.0 1 1 0 1 1 1 0 AAA domain CENP-M PF11111.8 KSA03906.1 - 0.082 12.1 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Centromere protein M (CENP-M) TniB PF05621.11 KSA03906.1 - 0.094 12.1 0.0 0.32 10.4 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein AAA_7 PF12775.7 KSA03906.1 - 0.12 11.9 0.1 0.29 10.7 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_5 PF07728.14 KSA03906.1 - 0.14 12.1 0.0 0.26 11.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 KSA03906.1 - 0.16 11.9 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Rpn3_C PF08375.11 KSA03907.1 - 1.2e-24 86.4 0.2 1.2e-24 86.4 0.2 2.0 2 0 0 2 2 2 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 KSA03907.1 - 8.3e-22 77.7 1.1 2.9e-21 75.9 0.2 2.4 3 0 0 3 3 3 1 PCI domain CSN8_PSD8_EIF3K PF10075.9 KSA03907.1 - 0.042 13.8 0.7 0.22 11.5 0.0 2.3 2 0 0 2 2 2 0 CSN8/PSMD8/EIF3K family Dynamin_N PF00350.23 KSA03907.1 - 0.064 13.3 1.0 0.18 11.9 0.5 1.9 2 0 0 2 2 2 0 Dynamin family Sigma70_r1_2 PF00140.20 KSA03907.1 - 0.27 11.3 1.6 0.69 10.0 1.0 2.1 2 0 0 2 2 2 0 Sigma-70 factor, region 1.2 Med17 PF10156.9 KSA03908.1 - 1.1e-112 377.2 17.1 1.3e-112 376.9 17.1 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex Ilm1 PF10311.9 KSA03909.1 - 2e-14 53.6 11.6 3.6e-10 39.7 4.0 2.0 1 1 1 2 2 2 2 Increased loss of mitochondrial DNA protein 1 Cu-oxidase_3 PF07732.15 KSA03910.1 - 6.4e-36 123.0 1.9 6.2e-35 119.8 0.3 2.5 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KSA03910.1 - 7.1e-30 103.5 4.2 1.1e-24 86.7 0.4 4.0 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 KSA03910.1 - 5.9e-11 42.7 0.0 4.7e-09 36.5 0.0 2.8 2 1 0 2 2 2 1 Multicopper oxidase Ribophorin_II PF05817.14 KSA03913.1 - 1.2e-15 57.2 1.0 1.4e-15 56.9 1.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II Peptidase_S24 PF00717.23 KSA03914.1 - 1.7e-06 27.9 0.0 4.8e-06 26.4 0.0 1.8 2 0 0 2 2 2 1 Peptidase S24-like Peptidase_S26 PF10502.9 KSA03914.1 - 0.032 14.0 0.0 0.081 12.7 0.0 1.6 1 1 0 1 1 1 0 Signal peptidase, peptidase S26 Ribosomal_S8 PF00410.19 KSA03915.1 - 6.1e-24 84.4 0.0 8e-24 84.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 CBFD_NFYB_HMF PF00808.23 KSA03917.1 - 4.3e-08 33.3 0.0 9.1e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KSA03917.1 - 0.00038 20.8 1.9 0.0014 19.0 0.0 2.2 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Cwf_Cwc_15 PF04889.12 KSA03917.1 - 6 6.5 16.0 0.24 11.1 3.4 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein MRP-L27 PF09809.9 KSA03918.1 - 3.2e-32 110.7 0.3 6e-32 109.8 0.3 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 DAO PF01266.24 KSA03920.1 - 1.3e-27 97.3 0.0 1.7e-27 96.9 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KSA03920.1 - 0.00022 20.6 0.0 0.001 18.4 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KSA03920.1 - 0.0003 21.0 0.1 0.0016 18.6 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KSA03920.1 - 0.0014 17.9 0.6 0.0063 15.8 0.1 2.2 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 KSA03920.1 - 0.0022 18.5 0.3 0.015 15.9 0.1 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KSA03920.1 - 0.0066 15.6 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 KSA03920.1 - 0.016 14.1 0.0 0.56 9.0 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Pyr_redox_3 PF13738.6 KSA03920.1 - 0.14 11.3 0.0 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KSA03920.1 - 0.18 10.8 0.0 0.36 9.8 0.0 1.4 2 0 0 2 2 2 0 Lycopene cyclase protein Glyco_hydro81C PF17652.1 KSA03921.1 - 1.5e-152 507.9 10.0 2.3e-152 507.3 10.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 KSA03921.1 - 1.4e-102 343.2 6.3 1.4e-102 343.2 6.3 2.8 3 1 1 4 4 4 1 Glycosyl hydrolase family 81 N-terminal domain DegQ PF08181.11 KSA03921.1 - 0.08 13.0 0.2 0.17 12.0 0.2 1.5 1 0 0 1 1 1 0 DegQ (SacQ) family Cnd1_N PF12922.7 KSA03921.1 - 6 6.7 9.0 1 9.2 0.1 3.1 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1, N-term GRASP55_65 PF04495.14 KSA03922.1 - 1e-47 161.9 0.0 4e-43 147.1 0.0 2.2 2 0 0 2 2 2 2 GRASP55/65 PDZ-like domain PfkB PF00294.24 KSA03923.1 - 1.4e-09 37.7 0.0 2.2e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 KSA03923.1 - 0.019 14.3 0.0 0.026 13.9 0.0 1.2 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase MFS_1 PF07690.16 KSA03924.1 - 4.4e-31 108.1 23.0 4.4e-31 108.1 23.0 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KSA03924.1 - 2.4e-12 46.5 18.3 5.5e-11 42.0 0.2 3.4 3 0 0 3 3 3 2 Sugar (and other) transporter Aminotran_3 PF00202.21 KSA03925.1 - 1.8e-59 201.5 0.0 2.2e-59 201.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Ank PF00023.30 KSA03926.1 - 5.5e-15 55.0 0.5 1.1e-05 25.6 0.1 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 KSA03926.1 - 2.8e-14 53.4 0.9 7.3e-06 26.5 0.4 3.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KSA03926.1 - 3.4e-13 49.8 3.2 3.9e-06 27.3 0.1 4.2 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KSA03926.1 - 4.7e-13 48.0 0.2 0.0003 21.0 0.1 4.2 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 KSA03926.1 - 7.4e-11 42.1 0.9 8.9e-05 22.7 0.1 3.7 3 0 0 3 3 3 2 Ankyrin repeats (many copies) KilA-N PF04383.13 KSA03926.1 - 4.4e-07 29.7 0.1 5.8e-06 26.1 0.1 2.8 1 1 0 1 1 1 1 KilA-N domain DUF3544 PF12064.8 KSA03927.1 - 0.057 13.7 1.1 0.097 12.9 0.6 1.6 2 0 0 2 2 2 0 Protein kinase C-binding protein 1 AKNA PF12443.8 KSA03927.1 - 0.42 11.3 3.6 0.16 12.6 0.7 1.8 2 0 0 2 2 2 0 AT-hook-containing transcription factor Aldedh PF00171.22 KSA03928.1 - 1.1e-161 538.4 0.0 1.3e-161 538.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KSA03928.1 - 0.0037 16.7 0.0 0.014 14.8 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1487) Sugar_tr PF00083.24 KSA03929.1 - 3.5e-67 227.2 21.7 4.4e-67 226.9 21.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KSA03929.1 - 6.5e-26 91.1 19.3 1e-25 90.5 19.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 KSA03929.1 - 1.3e-06 27.3 13.0 0.00011 20.9 4.6 2.3 2 1 0 2 2 2 2 MFS/sugar transport protein DUF4538 PF15061.6 KSA03929.1 - 0.24 11.1 0.6 1.7 8.4 0.6 2.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) DUF2264 PF10022.9 KSA03930.1 - 7.9e-115 383.7 0.1 9.8e-115 383.4 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) Glyco_hydro_88 PF07470.13 KSA03931.1 - 2.1e-08 33.6 0.5 3.2e-08 33.0 0.5 1.3 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 BNR_4 PF15892.5 KSA03932.1 - 9.1e-71 238.4 2.4 1.5e-70 237.7 2.4 1.2 1 0 0 1 1 1 1 BNR repeat-containing family member Glyco_hydro_43 PF04616.14 KSA03933.1 - 2.3e-05 23.8 1.4 5.4e-05 22.6 1.4 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.20 KSA03933.1 - 0.014 15.0 0.3 0.025 14.2 0.1 1.5 1 1 0 1 1 1 0 Glycosyl hydrolases family 32 N-terminal domain MF_alpha_N PF05436.11 KSA03933.1 - 0.02 14.8 0.0 0.036 13.9 0.0 1.5 1 0 0 1 1 1 0 Mating factor alpha precursor N-terminus Sugar_tr PF00083.24 KSA03935.1 - 5.3e-74 249.7 23.9 6.7e-74 249.4 23.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KSA03935.1 - 7.2e-25 87.7 21.0 1.1e-24 87.0 21.0 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KSA03935.1 - 0.00014 20.5 2.7 0.00024 19.6 2.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Glyco_hydro_2_C PF02836.17 KSA03936.1 - 6.5e-100 334.1 1.5 9.4e-100 333.6 0.1 2.0 3 0 0 3 3 3 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.17 KSA03936.1 - 3.2e-53 180.8 0.0 5.3e-53 180.1 0.0 1.3 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.18 KSA03936.1 - 4.8e-42 143.7 0.2 1.3e-41 142.4 0.2 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain DUF4981 PF16353.5 KSA03936.1 - 1.7e-16 60.5 0.0 4.5e-16 59.1 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function(DUF4981) Glyco_hydro_2 PF00703.21 KSA03936.1 - 8.6e-13 48.9 0.1 3.6e-12 46.9 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 UQ_con PF00179.26 KSA03937.1 - 2e-38 131.2 0.1 2.7e-38 130.8 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Polyoma_lg_T_C PF06431.11 KSA03937.1 - 0.021 13.7 2.1 0.033 13.1 2.1 1.2 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus Rho_GDI PF02115.17 KSA03938.1 - 1.3e-14 54.4 0.2 1.5e-14 54.2 0.2 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor NUP50 PF08911.11 KSA03939.1 - 1.9e-14 54.1 0.2 1.9e-14 54.1 0.2 2.9 3 1 0 3 3 3 1 NUP50 (Nucleoporin 50 kDa) Ribosomal_S25 PF03297.15 KSA03940.1 - 1e-38 131.6 5.4 1.1e-38 131.4 5.4 1.0 1 0 0 1 1 1 1 S25 ribosomal protein FtsK_gamma PF09397.10 KSA03940.1 - 0.00016 21.4 0.0 0.00023 20.9 0.0 1.3 1 0 0 1 1 1 1 Ftsk gamma domain HTH_CodY PF08222.11 KSA03940.1 - 0.012 15.1 0.2 0.02 14.5 0.2 1.3 1 0 0 1 1 1 0 CodY helix-turn-helix domain EAP30 PF04157.16 KSA03940.1 - 0.015 14.6 0.0 0.017 14.4 0.0 1.1 1 0 0 1 1 1 0 EAP30/Vps36 family GntR PF00392.21 KSA03940.1 - 0.022 14.4 0.0 0.032 13.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family Tctex-1 PF03645.13 KSA03940.1 - 0.028 14.6 0.1 0.034 14.4 0.1 1.1 1 0 0 1 1 1 0 Tctex-1 family DUF365 PF04033.12 KSA03940.1 - 0.047 14.0 0.3 0.068 13.4 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF365) HTH_24 PF13412.6 KSA03940.1 - 0.15 11.7 0.1 0.26 10.9 0.1 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Polyketide_cyc PF03364.20 KSA03941.1 - 5.9e-20 71.8 0.1 7e-20 71.6 0.1 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport PH_9 PF15410.6 KSA03942.1 - 5.3e-06 26.8 0.1 0.00055 20.3 0.1 2.6 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KSA03942.1 - 9.6e-06 26.1 2.5 0.0024 18.3 0.1 3.7 3 1 0 4 4 4 1 PH domain VGCC_beta4Aa_N PF12052.8 KSA03942.1 - 0.38 10.9 7.6 1.4 9.0 5.9 3.0 1 1 1 2 2 2 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal Glyco_hydro_20 PF00728.22 KSA03944.1 - 3.4e-103 345.8 1.7 3.4e-103 345.8 1.7 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 KSA03944.1 - 2e-23 83.6 0.2 4.1e-23 82.5 0.2 1.6 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 KSA03944.1 - 0.0014 19.4 0.0 0.0028 18.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Atx10homo_assoc PF09759.9 KSA03945.1 - 6.2e-36 122.4 0.9 6.2e-36 122.4 0.9 2.5 3 0 0 3 3 3 1 Spinocerebellar ataxia type 10 protein domain Thr_synth_N PF14821.6 KSA03946.1 - 7.4e-29 99.8 0.0 2.7e-28 98.0 0.0 2.0 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.25 KSA03946.1 - 8e-13 48.4 0.0 1.3e-12 47.7 0.0 1.3 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Tam41_Mmp37 PF09139.11 KSA03947.1 - 5.3e-110 367.8 0.7 7.4e-110 367.4 0.7 1.2 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial SAP30_Sin3_bdg PF13867.6 KSA03948.1 - 1.3e-10 41.4 0.2 2.4e-08 34.2 0.1 2.4 2 0 0 2 2 2 2 Sin3 binding region of histone deacetylase complex subunit SAP30 CUE PF02845.16 KSA03949.1 - 1.3e-09 37.5 0.0 2.5e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 CUE domain AMPKBI PF04739.15 KSA03949.1 - 0.013 15.7 0.3 0.026 14.8 0.3 1.5 1 0 0 1 1 1 0 5'-AMP-activated protein kinase beta subunit, interaction domain G2BR PF18442.1 KSA03949.1 - 0.026 14.2 2.2 0.048 13.3 2.2 1.4 1 0 0 1 1 1 0 E3 gp78 Ube2g2-binding region (G2BR) Cue1_U7BR PF18499.1 KSA03949.1 - 0.028 14.4 0.7 0.061 13.4 0.7 1.6 1 0 0 1 1 1 0 Ubc7p-binding region of Cue1 WD40 PF00400.32 KSA03950.1 - 3.6e-26 90.9 9.3 4.1e-05 24.2 0.2 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KSA03950.1 - 2.1e-18 66.4 0.1 0.0002 21.6 0.0 5.4 3 2 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KSA03950.1 - 1.4e-05 25.1 0.2 0.016 15.1 0.0 3.8 3 1 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KSA03950.1 - 0.0084 15.1 0.1 1.2 8.0 0.0 3.2 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KSA03950.1 - 0.01 15.2 2.2 0.63 9.3 0.0 3.2 3 0 0 3 3 3 0 WD40-like domain Peptidase_M18 PF02127.15 KSA03951.1 - 3.5e-123 411.6 0.0 4.1e-123 411.4 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Lactonase PF10282.9 KSA03952.1 - 0.067 12.4 0.6 0.087 12.1 0.6 1.1 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller TamB PF04357.13 KSA03952.1 - 7.1 5.8 10.6 0.19 10.9 1.5 1.9 1 1 1 2 2 2 0 TamB, inner membrane protein subunit of TAM complex Sugar_tr PF00083.24 KSA03953.1 - 3.3e-91 306.4 17.1 4e-91 306.2 17.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KSA03953.1 - 5.5e-27 94.6 29.2 5.5e-19 68.3 8.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Ribosomal_L7Ae PF01248.26 KSA03956.1 - 3e-29 100.6 0.1 9e-27 92.7 0.1 2.1 1 1 1 2 2 2 2 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Adaptin_N PF01602.20 KSA03958.1 - 1.3e-99 334.1 16.8 1.9e-99 333.6 16.8 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.6 KSA03958.1 - 2.8e-57 192.2 0.0 1.1e-56 190.4 0.0 2.1 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.12 KSA03958.1 - 5e-56 188.5 0.6 5e-56 188.5 0.6 2.2 2 0 0 2 2 2 1 Coatomer beta C-terminal region HEAT_2 PF13646.6 KSA03958.1 - 1.4e-09 38.2 1.4 0.00053 20.3 0.0 4.6 1 1 2 4 4 4 2 HEAT repeats Cnd1 PF12717.7 KSA03958.1 - 2.2e-08 34.3 13.3 1.5e-07 31.6 0.2 3.2 2 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KSA03958.1 - 3.8e-05 23.6 0.1 0.062 13.6 0.0 4.9 5 0 0 5 5 4 1 HEAT repeat Coatomer_g_Cpla PF16381.5 KSA03958.1 - 0.0034 17.5 0.0 0.013 15.6 0.0 2.1 2 0 0 2 2 2 1 Coatomer subunit gamma-1 C-terminal appendage platform AP4E_app_platf PF14807.6 KSA03958.1 - 0.0084 16.5 1.1 0.05 14.0 0.1 3.0 2 1 0 2 2 2 1 Adaptin AP4 complex epsilon appendage platform DUF5578 PF17741.1 KSA03958.1 - 0.011 15.2 9.4 0.02 14.3 0.7 2.9 1 1 1 2 2 2 0 Family of unknown function (DUF5578) HEAT_EZ PF13513.6 KSA03958.1 - 0.04 14.4 0.1 0.88 10.1 0.0 3.0 2 0 0 2 2 2 0 HEAT-like repeat CLTH PF10607.9 KSA03958.1 - 0.28 11.1 2.3 8.4 6.3 0.3 3.0 2 1 0 2 2 2 0 CTLH/CRA C-terminal to LisH motif domain Peptidase_M24 PF00557.24 KSA03960.1 - 2e-13 50.5 0.0 3.1e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 PHD PF00628.29 KSA03961.1 - 1.7e-09 37.4 30.0 3e-06 27.0 17.5 2.5 2 0 0 2 2 2 2 PHD-finger PHF12_MRG_bd PF16737.5 KSA03961.1 - 0.048 13.4 0.1 0.21 11.3 0.1 2.1 2 0 0 2 2 2 0 PHD finger protein 12 MRG binding domain L51_S25_CI-B8 PF05047.16 KSA03962.1 - 2e-12 46.8 0.4 3.3e-12 46.1 0.4 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain ArgJ PF01960.18 KSA03963.1 - 1.3e-144 481.6 3.2 1.4e-144 481.4 3.2 1.0 1 0 0 1 1 1 1 ArgJ family adh_short PF00106.25 KSA03965.1 - 1.2e-43 148.9 0.0 1.6e-43 148.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KSA03965.1 - 2.8e-32 112.2 0.0 3.8e-32 111.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KSA03965.1 - 5.5e-10 39.5 0.1 1.4e-09 38.1 0.1 1.6 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 KSA03965.1 - 6e-05 22.2 0.4 8.1e-05 21.7 0.4 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KSA03965.1 - 0.00078 19.0 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Iwr1 PF08574.10 KSA03966.1 - 2.6e-16 60.4 13.3 2.6e-16 60.4 13.3 3.2 2 1 0 2 2 2 1 Transcription factor Iwr1 RNA_pol PF00940.19 KSA03967.1 - 5.8e-143 476.7 3.7 9e-143 476.0 3.7 1.3 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 KSA03967.1 - 1.7e-26 93.4 0.0 4.7e-20 72.3 0.0 2.6 2 0 0 2 2 2 2 DNA-directed RNA polymerase N-terminal NRIP1_repr_4 PF15690.5 KSA03967.1 - 0.00092 18.6 0.2 0.0015 17.9 0.2 1.2 1 0 0 1 1 1 1 Nuclear receptor-interacting protein 1 repression 4 TRAPP PF04051.16 KSA03968.1 - 4.8e-39 133.4 0.0 5.7e-39 133.2 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component RRM_1 PF00076.22 KSA03969.1 - 5.5e-14 51.7 0.0 7.5e-12 44.9 0.0 3.1 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CDT1_C PF16679.5 KSA03970.1 - 0.08 13.4 1.9 0.68 10.4 0.0 2.5 1 1 1 2 2 2 0 DNA replication factor Cdt1 C-terminal domain Swi5 PF07061.11 KSA03970.1 - 0.1 12.7 0.2 0.1 12.7 0.2 1.7 2 0 0 2 2 2 0 Swi5 Pkinase PF00069.25 KSA03971.1 - 9.7e-46 156.3 0.3 1.3e-45 155.9 0.3 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KSA03971.1 - 4.5e-29 101.5 0.2 8.1e-29 100.7 0.2 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KSA03971.1 - 1.2e-09 37.9 0.0 1e-08 34.8 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KSA03971.1 - 0.00011 21.6 0.0 0.00017 21.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KSA03971.1 - 0.00038 20.5 0.0 0.00055 19.9 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KSA03971.1 - 0.0037 16.3 0.2 0.0054 15.7 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 KSA03971.1 - 0.01 15.5 0.2 0.024 14.2 0.1 1.7 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 YozE_SAM_like PF06855.12 KSA03971.1 - 0.015 15.5 1.0 0.051 13.8 1.0 1.9 1 0 0 1 1 1 0 YozE SAM-like fold RIO1 PF01163.22 KSA03971.1 - 0.026 14.1 0.4 0.064 12.8 0.4 1.7 1 1 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 KSA03971.1 - 0.063 12.0 0.0 0.094 11.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase MF_alpha_N PF05436.11 KSA03972.1 - 0.0046 16.8 0.5 0.0087 15.9 0.5 1.6 1 1 0 1 1 1 1 Mating factor alpha precursor N-terminus zf_C2H2_6 PF18450.1 KSA03972.1 - 0.0078 15.9 3.6 52 3.7 0.0 4.5 5 0 0 5 5 5 0 Zinc Finger domain Ribosomal_L28 PF00830.19 KSA03972.1 - 0.013 15.6 7.7 24 5.2 0.8 4.6 1 1 3 4 4 4 0 Ribosomal L28 family Apidaecin PF00807.17 KSA03972.1 - 7 6.8 10.4 76 3.5 0.1 4.7 5 0 0 5 5 5 0 Apidaecin SH3_1 PF00018.28 KSA03973.1 - 1.5e-06 27.7 0.7 1.7e-05 24.3 0.7 2.5 1 1 0 1 1 1 1 SH3 domain BAR PF03114.18 KSA03973.1 - 1.9e-06 27.7 6.4 1.9e-06 27.7 6.4 2.2 2 0 0 2 2 2 1 BAR domain SH3_9 PF14604.6 KSA03973.1 - 0.00045 20.0 0.0 0.00082 19.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KSA03973.1 - 0.0089 15.7 0.0 0.02 14.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Wbp11 PF09429.10 KSA03973.1 - 0.089 13.2 5.5 0.49 10.8 5.5 2.3 1 0 0 1 1 1 0 WW domain binding protein 11 NAAA-beta PF15508.6 KSA03973.1 - 0.15 12.4 2.6 50 4.3 0.1 4.1 3 0 0 3 3 3 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Seryl_tRNA_N PF02403.22 KSA03973.1 - 0.24 11.6 6.6 0.069 13.4 2.4 2.3 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain CEP63 PF17045.5 KSA03973.1 - 0.68 9.8 11.4 0.088 12.7 5.8 2.3 2 1 0 2 2 2 0 Centrosomal protein of 63 kDa PRP1_N PF06424.12 KSA03973.1 - 1.2 9.5 5.2 1.6 9.1 1.5 2.7 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal Baculo_PEP_C PF04513.12 KSA03973.1 - 3.6 7.6 5.6 3.9 7.5 1.1 3.0 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Abhydrolase_1 PF00561.20 KSA03974.1 - 3.1e-11 43.4 0.0 5.1e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KSA03974.1 - 1.7e-05 24.2 0.0 0.00021 20.6 0.0 2.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 HEAT_2 PF13646.6 KSA03975.1 - 2.4e-08 34.2 0.0 0.0017 18.7 0.0 4.4 3 1 1 4 4 4 2 HEAT repeats HEAT PF02985.22 KSA03975.1 - 0.00016 21.6 0.1 1.6 9.2 0.1 5.1 5 0 0 5 5 5 1 HEAT repeat Cnd1 PF12717.7 KSA03975.1 - 0.00054 20.0 0.7 0.00054 20.0 0.7 4.7 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 KSA03975.1 - 0.001 19.6 0.8 0.94 10.1 0.0 4.9 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 KSA03975.1 - 0.0011 18.6 3.6 0.021 14.4 0.4 3.2 2 0 0 2 2 2 1 CLASP N terminal VHS PF00790.19 KSA03975.1 - 0.0018 18.2 1.8 0.17 11.7 0.1 4.1 4 0 0 4 4 4 1 VHS domain Anticodon_1 PF08264.13 KSA03975.1 - 0.028 14.4 0.4 0.24 11.3 0.0 2.7 2 0 0 2 2 2 0 Anticodon-binding domain of tRNA Arm PF00514.23 KSA03975.1 - 0.088 12.9 0.1 36 4.6 0.0 4.0 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat DUF3385 PF11865.8 KSA03975.1 - 0.34 10.8 2.2 43 4.0 0.0 4.6 4 1 1 5 5 5 0 Domain of unknown function (DUF3385) GLE1 PF07817.13 KSA03976.1 - 2.7e-82 275.8 2.1 2.7e-82 275.8 2.1 1.6 2 0 0 2 2 2 1 GLE1-like protein MAP7 PF05672.11 KSA03976.1 - 0.0055 16.4 56.1 0.01 15.5 56.1 1.4 1 0 0 1 1 1 1 MAP7 (E-MAP-115) family NPR3 PF03666.13 KSA03976.1 - 0.041 12.7 23.1 0.081 11.7 23.1 1.4 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RR_TM4-6 PF06459.12 KSA03976.1 - 0.13 12.0 27.8 0.25 11.1 27.8 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF5401 PF17380.2 KSA03976.1 - 0.45 8.5 39.3 0.59 8.1 39.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Presenilin PF01080.17 KSA03976.1 - 2.4 6.8 20.1 3.3 6.4 20.1 1.2 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 KSA03976.1 - 3.9 7.5 11.2 6.5 6.7 11.2 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region GAGA_bind PF06217.12 KSA03976.1 - 5.6 7.2 20.7 9.5 6.4 20.7 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family SOBP PF15279.6 KSA03976.1 - 6.9 7.2 8.2 11 6.5 8.2 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein CDC45 PF02724.14 KSA03976.1 - 10 4.3 28.8 14 3.8 28.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Ribosomal_L5_C PF00673.21 KSA03977.1 - 1.7e-29 101.8 0.0 2.8e-29 101.1 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 KSA03977.1 - 0.035 14.4 0.0 0.091 13.1 0.0 1.7 1 0 0 1 1 1 0 Ribosomal protein L5 DUF2439 PF10382.9 KSA03978.1 - 1.7e-21 76.3 1.8 3.1e-21 75.5 1.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) motB PF17613.2 KSA03979.1 - 0.014 15.3 0.0 0.02 14.7 0.0 1.2 1 0 0 1 1 1 0 Modifier of transcription zf-C2H2_4 PF13894.6 KSA03980.1 - 2.8e-06 27.7 15.0 0.0065 17.2 0.6 4.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KSA03980.1 - 0.00013 22.2 1.0 0.00013 22.2 1.0 3.8 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2HC_2 PF13913.6 KSA03980.1 - 0.017 15.0 0.5 2.5 8.1 0.1 2.7 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_3rep PF18868.1 KSA03980.1 - 0.02 15.6 5.1 5.4 7.7 1.9 2.9 2 1 1 3 3 3 0 Zinc finger C2H2-type, 3 repeats Ogr_Delta PF04606.12 KSA03980.1 - 0.073 13.1 0.2 0.19 11.7 0.2 1.7 1 0 0 1 1 1 0 Ogr/Delta-like zinc finger zf-C2H2_11 PF16622.5 KSA03980.1 - 0.092 12.5 0.1 0.092 12.5 0.1 3.5 4 0 0 4 4 4 0 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 KSA03980.1 - 0.41 10.7 3.5 0.71 9.9 0.2 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KSA03980.1 - 0.82 9.5 10.6 2.1 8.2 0.1 3.3 3 0 0 3 3 3 0 C2H2-type zinc-finger domain NRDE-2 PF08424.10 KSA03981.1 - 0.057 12.5 8.2 0.052 12.7 2.6 3.1 2 2 1 3 3 3 0 NRDE-2, necessary for RNA interference TPR_12 PF13424.6 KSA03981.1 - 0.084 13.2 0.1 1.2 9.4 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KSA03981.1 - 0.15 12.9 0.0 39 5.4 0.0 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 KSA03981.1 - 0.43 11.1 2.4 14 6.3 0.3 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 KSA03981.1 - 1.4 9.0 13.8 5.1 7.1 0.0 4.7 4 2 1 5 5 5 0 Mad3/BUB1 homology region 1 Na_Ca_ex PF01699.24 KSA03982.1 - 2.1e-13 50.5 18.7 2.1e-13 50.5 18.7 2.7 3 0 0 3 3 3 2 Sodium/calcium exchanger protein Flavokinase PF01687.17 KSA03983.1 - 1.6e-24 86.4 0.0 1.9e-24 86.1 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase TAL_FSA PF00923.19 KSA03984.1 - 2.8e-98 328.8 0.9 3.1e-98 328.7 0.9 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase ExbD PF02472.16 KSA03984.1 - 0.074 13.2 2.2 11 6.1 0.1 2.9 2 1 1 3 3 3 0 Biopolymer transport protein ExbD/TolR DUF1769 PF08588.10 KSA03985.1 - 2.5e-21 75.6 0.1 4.3e-21 74.9 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) DUF3020 PF11223.8 KSA03986.1 - 1.4e-20 73.5 9.9 1.4e-20 73.5 9.9 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3020) UIM PF02809.20 KSA03986.1 - 4 7.6 8.4 24 5.1 0.2 4.0 3 0 0 3 3 3 0 Ubiquitin interaction motif LRAT PF04970.13 KSA03986.1 - 9.6 6.5 11.1 13 6.1 0.3 4.1 4 0 0 4 4 4 0 Lecithin retinol acyltransferase Creatinase_N_2 PF16189.5 KSA03987.1 - 3.8e-42 144.1 0.2 1.9e-41 141.8 0.4 2.0 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 KSA03987.1 - 2.3e-34 118.9 0.0 3.3e-34 118.4 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 KSA03987.1 - 1.2e-17 63.7 0.1 2.5e-17 62.7 0.1 1.6 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 KSA03987.1 - 2.6e-10 41.0 0.0 1.2e-09 38.9 0.0 2.0 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain SMC_N PF02463.19 KSA03988.1 - 4.2e-61 206.2 7.0 8.8e-61 205.1 7.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KSA03988.1 - 5e-24 84.9 0.1 3.4e-23 82.2 0.1 2.5 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 KSA03988.1 - 3e-11 44.2 23.1 3e-11 44.2 23.1 7.6 2 2 3 6 6 2 1 AAA domain AAA_21 PF13304.6 KSA03988.1 - 3.3e-08 33.7 24.5 2.1e-05 24.5 0.8 4.5 3 2 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KSA03988.1 - 3.9e-08 33.4 37.1 3.9e-08 33.4 37.1 4.6 2 2 2 4 4 1 1 AAA ATPase domain AAA_29 PF13555.6 KSA03988.1 - 1.4e-06 27.9 0.1 3.2e-06 26.8 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain FPP PF05911.11 KSA03988.1 - 3.7e-05 22.1 30.8 3.7e-05 22.1 30.8 4.5 2 2 1 3 3 2 1 Filament-like plant protein, long coiled-coil DUF3450 PF11932.8 KSA03988.1 - 0.0017 17.7 7.3 0.0017 17.7 7.3 7.6 4 2 5 9 9 9 1 Protein of unknown function (DUF3450) CENP-F_leu_zip PF10473.9 KSA03988.1 - 0.0088 16.1 21.4 0.0088 16.1 21.4 7.6 5 2 2 7 7 6 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_27 PF13514.6 KSA03988.1 - 0.027 14.1 0.1 0.027 14.1 0.1 5.1 5 1 1 6 6 6 0 AAA domain SbcCD_C PF13558.6 KSA03988.1 - 0.055 13.7 0.0 0.22 11.7 0.0 2.1 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit ABC_tran PF00005.27 KSA03988.1 - 0.072 13.6 0.2 0.072 13.6 0.2 6.1 4 3 1 5 5 4 0 ABC transporter partial_CstF PF15861.5 KSA03988.1 - 0.097 12.5 4.4 0.43 10.4 4.4 2.2 1 0 0 1 1 1 0 Partial cleavage stimulation factor domain T3SSipB PF16535.5 KSA03988.1 - 3.5 8.1 42.4 3 8.3 1.8 5.5 5 0 0 5 5 5 0 Type III cell invasion protein SipB tRNA_U5-meth_tr PF05958.11 KSA03989.1 - 1e-16 60.9 0.3 3.3e-15 55.9 0.1 2.2 1 1 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.6 KSA03989.1 - 1.6e-06 28.0 0.0 3.8e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 KSA03989.1 - 2.5e-05 23.6 0.1 4.5e-05 22.7 0.1 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_25 PF13649.6 KSA03989.1 - 0.00018 22.1 0.0 0.00046 20.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain TRM PF02005.16 KSA03989.1 - 0.00039 19.7 0.0 0.0012 18.1 0.0 1.8 1 1 1 2 2 2 1 N2,N2-dimethylguanosine tRNA methyltransferase Ubie_methyltran PF01209.18 KSA03989.1 - 0.00069 19.0 0.0 0.0013 18.2 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 KSA03989.1 - 0.0016 18.5 0.0 0.0036 17.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain TRAM PF01938.20 KSA03989.1 - 0.0017 18.3 1.1 0.0046 16.9 0.1 2.2 3 0 0 3 3 3 1 TRAM domain MTS PF05175.14 KSA03989.1 - 0.0038 16.8 0.0 0.0075 15.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 KSA03989.1 - 0.0056 16.1 0.2 0.016 14.6 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Met_10 PF02475.16 KSA03989.1 - 0.023 14.4 0.1 0.22 11.2 0.0 2.3 2 0 0 2 2 2 0 Met-10+ like-protein MA3 PF02847.17 KSA03990.1 - 5e-23 81.2 0.0 2.8e-22 78.8 0.0 2.4 2 0 0 2 2 2 1 MA3 domain MIF4G PF02854.19 KSA03990.1 - 1.1e-21 77.5 8.1 6.4e-19 68.4 6.5 2.5 2 0 0 2 2 2 2 MIF4G domain AAA PF00004.29 KSA03991.1 - 3.4e-36 124.6 0.0 5.6e-36 123.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KSA03991.1 - 4.2e-11 42.5 0.0 9.9e-11 41.3 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KSA03991.1 - 4.9e-06 27.0 0.5 0.00093 19.6 0.0 3.0 2 1 0 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 KSA03991.1 - 1.1e-05 25.3 0.0 3.8e-05 23.5 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KSA03991.1 - 2.3e-05 24.6 0.0 4.8e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 KSA03991.1 - 3.4e-05 23.9 0.0 7.3e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KSA03991.1 - 8.7e-05 22.7 0.0 0.0002 21.5 0.0 1.7 2 1 0 2 2 1 1 AAA domain AAA_5 PF07728.14 KSA03991.1 - 8.8e-05 22.5 0.2 0.0011 19.0 0.2 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Parvo_NS1 PF01057.17 KSA03991.1 - 0.00045 19.4 0.0 0.00076 18.7 0.0 1.4 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_18 PF13238.6 KSA03991.1 - 0.00083 19.9 0.0 0.0016 19.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KSA03991.1 - 0.00093 19.5 0.6 0.034 14.4 0.3 3.0 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KSA03991.1 - 0.001 18.9 0.0 0.0018 18.1 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 KSA03991.1 - 0.0011 18.4 0.0 0.0025 17.2 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 KSA03991.1 - 0.0017 18.7 0.0 0.0037 17.6 0.0 1.6 1 1 0 1 1 1 1 RNA helicase Sigma54_activ_2 PF14532.6 KSA03991.1 - 0.0019 18.3 0.0 0.0033 17.6 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain Hydin_ADK PF17213.3 KSA03991.1 - 0.0026 18.1 0.1 1.2 9.4 0.0 2.5 3 0 0 3 3 2 1 Hydin Adenylate kinase-like domain AAA_24 PF13479.6 KSA03991.1 - 0.0044 16.8 0.0 0.0071 16.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 KSA03991.1 - 0.0049 16.1 0.0 0.0092 15.2 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_7 PF12775.7 KSA03991.1 - 0.0057 16.2 0.1 0.025 14.1 0.1 2.0 1 1 0 1 1 1 1 P-loop containing dynein motor region NACHT PF05729.12 KSA03991.1 - 0.0077 16.2 0.4 0.03 14.2 0.1 2.1 3 0 0 3 3 3 1 NACHT domain TIP49 PF06068.13 KSA03991.1 - 0.0081 15.4 0.1 0.017 14.3 0.1 1.5 1 1 0 1 1 1 1 TIP49 P-loop domain Bac_DnaA PF00308.18 KSA03991.1 - 0.0085 15.9 0.0 0.016 15.0 0.0 1.4 1 1 0 1 1 1 1 Bacterial dnaA protein TniB PF05621.11 KSA03991.1 - 0.0089 15.5 0.0 4 6.8 0.0 2.3 2 0 0 2 2 2 1 Bacterial TniB protein NB-ARC PF00931.22 KSA03991.1 - 0.016 14.4 0.0 0.063 12.5 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain Rad17 PF03215.15 KSA03991.1 - 0.017 15.0 0.2 0.05 13.5 0.2 2.0 1 1 0 1 1 1 0 Rad17 P-loop domain AAA_25 PF13481.6 KSA03991.1 - 0.026 14.1 0.1 0.79 9.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KSA03991.1 - 0.029 14.9 0.0 0.062 13.8 0.0 1.9 1 1 0 1 1 1 0 ABC transporter ATPase_2 PF01637.18 KSA03991.1 - 0.032 14.1 0.4 0.12 12.2 0.0 2.1 2 1 1 3 3 2 0 ATPase domain predominantly from Archaea Viral_helicase1 PF01443.18 KSA03991.1 - 0.057 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_17 PF13207.6 KSA03991.1 - 0.06 13.8 0.0 0.16 12.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KSA03991.1 - 0.068 12.4 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Sigma54_activat PF00158.26 KSA03991.1 - 0.073 12.8 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain TsaE PF02367.17 KSA03991.1 - 0.076 13.0 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 KSA03991.1 - 0.076 13.2 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 KSA03991.1 - 0.1 12.0 0.2 5.3 6.4 0.1 2.5 3 0 0 3 3 2 0 RecF/RecN/SMC N terminal domain AAA_6 PF12774.7 KSA03991.1 - 0.19 10.6 0.0 0.33 9.9 0.0 1.3 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region RNA12 PF10443.9 KSA03992.1 - 2.1e-163 544.2 16.9 4e-105 352.1 3.2 3.0 2 1 1 3 3 3 2 RNA12 protein ATPase_2 PF01637.18 KSA03992.1 - 1.6e-06 28.2 17.1 0.0033 17.4 0.1 3.9 4 0 0 4 4 4 2 ATPase domain predominantly from Archaea RRM_1 PF00076.22 KSA03992.1 - 0.00014 21.6 0.0 0.00071 19.3 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2487 PF10673.9 KSA03992.1 - 0.00089 19.3 0.5 0.0073 16.3 0.1 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF2487) Peptidase_C48 PF02902.19 KSA03993.1 - 3e-34 118.8 3.7 3e-34 118.8 3.7 1.6 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain LupA PF18242.1 KSA03993.1 - 0.048 13.3 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Legionella ubiquitin-specific protease A domain VTC PF09359.10 KSA03994.1 - 1.8e-91 306.4 1.1 3.7e-91 305.3 1.1 1.5 1 0 0 1 1 1 1 VTC domain DUF202 PF02656.15 KSA03994.1 - 2.5e-11 43.9 1.7 2.5e-11 43.9 1.7 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF202) SPX PF03105.19 KSA03994.1 - 2.4e-09 37.6 24.7 0.00018 21.5 1.2 4.4 2 1 2 4 4 4 3 SPX domain Clat_adaptor_s PF01217.20 KSA03995.1 - 1.6e-14 54.1 1.9 2e-14 53.7 1.9 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF3496 PF12001.8 KSA03995.1 - 0.018 15.4 1.4 0.032 14.6 1.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3496) ArlS_N PF18719.1 KSA03995.1 - 0.02 15.1 4.2 0.028 14.6 3.0 1.9 1 1 1 2 2 2 0 ArlS sensor domain DUF4367 PF14285.6 KSA03995.1 - 0.19 12.2 2.9 0.31 11.5 2.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4367) Bromo_TP PF07524.13 KSA03996.1 - 1.1e-10 41.3 0.0 2.4e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 Bromodomain associated Bromo_TP_like PF17027.5 KSA03996.1 - 0.00051 20.2 0.9 0.00051 20.2 0.9 2.7 2 1 0 2 2 2 1 Histone-fold protein TFIID-31kDa PF02291.15 KSA03996.1 - 0.0041 17.2 0.0 0.012 15.6 0.0 1.8 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit DGF-1_C PF11040.8 KSA03997.1 - 0.49 10.4 1.8 1.7 8.7 0.5 2.5 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus Exo5 PF09810.9 KSA03998.1 - 4.5e-48 164.6 4.6 1.5e-33 116.8 0.5 2.1 2 0 0 2 2 2 2 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.7 KSA03998.1 - 3.9e-07 30.2 0.6 0.01 15.8 0.0 2.4 2 0 0 2 2 2 2 PD-(D/E)XK nuclease superfamily FTO_CTD PF12934.7 KSA03998.1 - 0.014 15.2 0.7 0.048 13.4 0.0 2.2 3 0 0 3 3 3 0 FTO C-terminal domain zf-H2C2_5 PF13909.6 KSA03998.1 - 0.23 11.2 2.8 0.7 9.7 2.8 1.8 1 0 0 1 1 1 0 C2H2-type zinc-finger domain DDR PF08841.10 KSA03998.1 - 0.25 10.3 0.1 0.97 8.4 0.1 1.7 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain Sugar_tr PF00083.24 KSA03999.1 - 4.2e-88 296.2 19.8 5.1e-88 295.9 19.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KSA03999.1 - 7.8e-33 113.9 24.1 7.8e-33 113.9 24.1 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Folate_carrier PF01770.18 KSA03999.1 - 7.6e-06 24.9 0.1 1e-05 24.5 0.1 1.2 1 0 0 1 1 1 1 Reduced folate carrier TRI12 PF06609.13 KSA03999.1 - 5e-05 21.9 6.6 0.00043 18.8 1.8 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) DcpS_C PF11969.8 KSA04000.1 - 1.7e-20 73.6 3.1 2.9e-20 72.9 3.1 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding zf-C2HE PF16278.5 KSA04000.1 - 1.4e-14 54.3 0.8 4e-14 52.8 0.8 1.8 1 1 0 1 1 1 1 C2HE / C2H2 / C2HC zinc-binding finger HIT PF01230.23 KSA04000.1 - 8.4e-14 52.1 0.4 6.9e-13 49.2 0.1 2.1 2 0 0 2 2 2 1 HIT domain zf-H2C2_2 PF13465.6 KSA04000.1 - 0.036 14.5 0.9 0.39 11.2 0.0 2.5 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 KSA04000.1 - 0.044 14.6 0.4 0.044 14.6 0.4 2.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KSA04000.1 - 4.1 8.1 6.8 4.6 7.9 2.3 3.1 2 1 0 2 2 2 0 Zinc finger, C2H2 type Pkr1 PF08636.10 KSA04001.1 - 4.4e-30 103.6 8.4 5.2e-30 103.4 8.4 1.1 1 0 0 1 1 1 1 ER protein Pkr1 zf-RING_4 PF14570.6 KSA04002.1 - 3.6e-20 71.5 12.3 7.1e-20 70.5 12.3 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.22 KSA04002.1 - 1e-07 31.7 0.0 4.1e-07 29.7 0.0 2.1 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.6 KSA04002.1 - 2.1e-05 24.3 7.5 2.1e-05 24.3 7.5 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Baculo_IE-1 PF05290.11 KSA04002.1 - 0.0001 22.3 4.6 0.00028 20.8 4.6 1.7 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-RING_2 PF13639.6 KSA04002.1 - 0.0065 16.8 9.9 0.014 15.7 9.9 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KSA04002.1 - 0.01 15.7 10.3 0.024 14.5 10.3 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KSA04002.1 - 0.011 15.6 7.1 0.3 11.0 7.5 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Nup35_RRM_2 PF14605.6 KSA04002.1 - 0.11 12.6 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif SUIM_assoc PF16619.5 KSA04002.1 - 0.74 9.9 0.0 0.74 9.9 0.0 6.9 4 1 1 5 5 4 0 Unstructured region C-term to UIM in Ataxin3 zf-RING_UBOX PF13445.6 KSA04002.1 - 1.3 9.1 9.3 4 7.5 9.3 1.9 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 KSA04002.1 - 2.2 8.3 9.9 4.8 7.2 9.9 1.6 1 0 0 1 1 1 0 zinc-RING finger domain tRNA-synt_1 PF00133.22 KSA04004.1 - 4.9e-154 513.9 0.3 6.9e-154 513.4 0.3 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 KSA04004.1 - 6.5e-22 77.8 0.1 5.3e-13 48.5 0.0 3.6 3 0 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 KSA04004.1 - 4.6e-19 68.9 0.2 1.3e-18 67.4 0.2 1.8 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1_2 PF13603.6 KSA04004.1 - 0.016 14.7 0.0 0.035 13.6 0.0 1.6 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 Prok-RING_1 PF14446.6 KSA04004.1 - 0.056 13.4 2.3 0.12 12.3 2.3 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Citrate_synt PF00285.21 KSA04005.1 - 9.5e-101 337.4 0.0 1.2e-100 337.1 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain PSCyt2 PF07583.11 KSA04005.1 - 0.18 11.7 0.0 0.64 9.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1549) DSPc PF00782.20 KSA04006.1 - 9.3e-26 90.2 0.1 1.6e-25 89.4 0.1 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KSA04006.1 - 0.0038 16.8 0.0 0.0076 15.8 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Elf1 PF05129.13 KSA04006.1 - 0.011 15.7 0.2 8.1 6.6 0.0 2.6 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like Init_tRNA_PT PF04179.12 KSA04006.1 - 0.1 12.9 0.0 0.3 11.4 0.0 1.9 1 1 0 1 1 1 0 Rit1 DUSP-like domain zinc_ribbon_4 PF13717.6 KSA04006.1 - 0.28 11.1 4.3 1.4 8.9 0.5 2.8 2 0 0 2 2 2 0 zinc-ribbon domain Zn_ribbon_SprT PF17283.2 KSA04006.1 - 0.32 11.0 0.0 0.32 11.0 0.0 2.9 3 0 0 3 3 3 0 SprT-like zinc ribbon domain zinc_ribbon_5 PF13719.6 KSA04006.1 - 1.4 8.7 6.8 14 5.5 0.3 3.6 3 0 0 3 3 3 0 zinc-ribbon domain Apc15p PF05841.11 KSA04007.1 - 1.3e-27 97.0 2.8 1.3e-27 97.0 2.8 2.0 2 0 0 2 2 2 1 Apc15p protein Alpha_GJ PF03229.13 KSA04007.1 - 0.38 11.3 5.1 0.73 10.4 1.1 2.1 2 0 0 2 2 2 0 Alphavirus glycoprotein J RseA_C PF03873.13 KSA04007.1 - 3.6 7.9 6.9 5.3 7.4 0.4 3.0 3 0 0 3 3 3 0 Anti sigma-E protein RseA, C-terminal domain CTU2 PF10288.9 KSA04008.1 - 1.3e-22 80.1 1.0 1.3e-22 80.1 1.0 2.0 2 0 0 2 2 2 1 Cytoplasmic tRNA 2-thiolation protein 2 zinc_ribbon_15 PF17032.5 KSA04008.1 - 0.09 13.5 8.6 0.39 11.5 2.0 3.2 3 0 0 3 3 3 0 zinc-ribbon family DZR PF12773.7 KSA04008.1 - 0.52 10.4 6.1 9.1 6.4 0.4 2.7 2 1 0 2 2 2 0 Double zinc ribbon zf-FPG_IleRS PF06827.14 KSA04008.1 - 1 9.3 5.3 1.4 8.8 1.7 2.6 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS Rpr2 PF04032.16 KSA04008.1 - 9.8 6.5 7.2 7.5 6.9 1.4 2.9 2 1 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain COX17 PF05051.13 KSA04009.1 - 0.00034 20.9 3.4 0.00067 20.0 3.4 1.5 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) CHCH PF06747.13 KSA04009.1 - 0.0044 17.1 6.8 0.009 16.1 6.8 1.6 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.9 KSA04009.1 - 0.037 14.3 7.5 0.11 12.8 7.4 1.8 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 Multi_ubiq PF14452.6 KSA04009.1 - 0.064 13.5 0.3 0.1 12.9 0.3 1.3 1 0 0 1 1 1 0 Multiubiquitin Cmc1 PF08583.10 KSA04009.1 - 4.2 7.5 10.5 1.6 8.8 1.5 2.6 2 1 1 3 3 3 0 Cytochrome c oxidase biogenesis protein Cmc1 like YL1 PF05764.13 KSA04011.1 - 4.1e-05 23.8 3.8 4.1e-05 23.8 3.8 1.6 2 0 0 2 2 2 1 YL1 nuclear protein Merozoite_SPAM PF07133.11 KSA04011.1 - 0.0032 17.5 11.4 0.0032 17.5 11.4 1.6 2 0 0 2 2 2 1 Merozoite surface protein (SPAM) DNA_pol_phi PF04931.13 KSA04011.1 - 4.2 5.4 16.0 6.1 4.8 16.0 1.2 1 0 0 1 1 1 0 DNA polymerase phi PH PF00169.29 KSA04012.1 - 5.8e-15 55.7 0.0 3e-14 53.4 0.0 2.3 1 0 0 1 1 1 1 PH domain SH3_1 PF00018.28 KSA04012.1 - 3.7e-08 32.9 0.1 1.2e-07 31.2 0.1 1.9 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KSA04012.1 - 3.8e-08 33.1 0.0 8.1e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SAM_2 PF07647.17 KSA04012.1 - 4.5e-07 29.9 0.0 9.6e-07 28.8 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH_8 PF15409.6 KSA04012.1 - 0.0079 16.4 0.1 0.79 10.0 0.0 3.2 3 0 0 3 3 3 1 Pleckstrin homology domain PH_11 PF15413.6 KSA04012.1 - 0.031 14.7 3.5 0.2 12.1 0.2 3.7 2 1 0 2 2 2 0 Pleckstrin homology domain SAM_1 PF00536.30 KSA04012.1 - 0.059 13.8 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Agenet PF05641.12 KSA04012.1 - 0.071 13.6 0.0 0.26 11.8 0.0 2.0 1 0 0 1 1 1 0 Agenet domain SH3_2 PF07653.17 KSA04012.1 - 0.13 11.9 0.0 0.31 10.8 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain TPR_2 PF07719.17 KSA04013.1 - 5e-29 98.0 17.0 1.2e-05 25.0 0.0 10.7 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_1 PF00515.28 KSA04013.1 - 3.5e-25 86.7 21.3 1.5e-07 31.0 0.0 9.0 10 0 0 10 10 10 6 Tetratricopeptide repeat ANAPC3 PF12895.7 KSA04013.1 - 5.5e-25 87.4 20.7 2.9e-19 69.1 5.1 4.3 4 0 0 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 KSA04013.1 - 1.2e-24 84.4 16.7 0.00012 22.0 0.1 9.1 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_12 PF13424.6 KSA04013.1 - 7.1e-14 51.9 3.4 0.06 13.6 0.1 7.0 7 2 0 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 KSA04013.1 - 9.9e-13 48.5 0.0 0.0048 17.5 0.0 5.7 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 KSA04013.1 - 1.4e-11 43.9 17.7 0.00042 19.9 0.3 9.2 5 2 6 11 11 11 5 TPR repeat TPR_17 PF13431.6 KSA04013.1 - 1.8e-11 43.6 13.9 2.2 8.9 0.0 9.3 9 1 0 9 9 8 2 Tetratricopeptide repeat TPR_19 PF14559.6 KSA04013.1 - 2.4e-09 37.6 6.6 0.067 13.7 0.1 6.2 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 KSA04013.1 - 5.3e-08 32.4 0.4 0.81 9.9 0.0 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 KSA04013.1 - 9.4e-08 32.3 0.0 1.3 10.1 0.0 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 KSA04013.1 - 2.2e-07 31.1 2.8 0.17 12.6 0.0 6.3 7 0 0 7 7 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 KSA04013.1 - 7.9e-07 29.1 0.0 0.077 13.1 0.0 3.5 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_15 PF13429.6 KSA04013.1 - 0.0057 15.9 0.1 2.8 7.1 0.0 3.2 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_3 PF07720.12 KSA04013.1 - 0.62 10.1 10.5 0.36 10.9 0.6 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 KSA04013.1 - 0.83 9.6 3.2 32 4.6 0.0 4.6 5 1 1 6 6 6 0 Tetratricopeptide repeat EMP70 PF02990.16 KSA04014.1 - 2.7e-155 518.0 22.9 3.3e-155 517.7 22.9 1.0 1 0 0 1 1 1 1 Endomembrane protein 70 TMEM156 PF15106.6 KSA04014.1 - 0.021 14.3 0.1 0.89 9.0 0.1 2.7 2 0 0 2 2 2 0 TMEM156 protein family ATP-synt PF00231.19 KSA04015.1 - 6e-76 255.8 7.6 6.8e-76 255.6 7.6 1.0 1 0 0 1 1 1 1 ATP synthase NDUFB10 PF10249.9 KSA04016.1 - 0.00086 19.8 0.2 0.00097 19.6 0.2 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 Frag1 PF10277.9 KSA04017.1 - 1.1e-43 149.3 12.5 1.1e-43 149.3 12.5 3.6 4 0 0 4 4 4 1 Frag1/DRAM/Sfk1 family Nefa_Nip30_N PF10187.9 KSA04018.1 - 2.6e-14 53.5 23.8 5.5e-14 52.4 23.8 1.5 1 0 0 1 1 1 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF572 PF04502.13 KSA04018.1 - 0.85 9.2 23.8 1.1 8.8 23.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) MCU PF04678.13 KSA04018.1 - 8.9 6.4 9.2 18 5.4 9.2 1.5 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Ribosomal_L35p PF01632.19 KSA04019.1 - 1.3e-13 51.2 4.5 1.7e-13 50.8 4.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L35 Pox_T4_N PF04491.12 KSA04019.1 - 0.11 12.4 0.0 0.24 11.2 0.0 1.7 1 0 0 1 1 1 0 Poxvirus T4 protein, N terminus PDZ_1 PF12812.7 KSA04020.1 - 2.7e-51 171.5 1.1 2.2e-35 120.5 0.0 3.8 4 0 0 4 4 4 2 PDZ-like domain Trypsin_2 PF13365.6 KSA04020.1 - 8.3e-25 88.4 0.3 1.5e-20 74.6 0.1 2.8 2 0 0 2 2 2 2 Trypsin-like peptidase domain PDZ_2 PF13180.6 KSA04020.1 - 1.3e-17 63.9 2.0 9.2e-05 22.7 0.0 4.4 4 0 0 4 4 4 3 PDZ domain PDZ_6 PF17820.1 KSA04020.1 - 4e-16 58.6 0.1 1.1e-08 34.8 0.0 4.2 4 0 0 4 4 4 3 PDZ domain PDZ PF00595.24 KSA04020.1 - 5.1e-13 49.2 0.0 8.9e-06 26.0 0.0 3.6 3 0 0 3 3 3 3 PDZ domain Trypsin PF00089.26 KSA04020.1 - 6.6e-05 22.8 0.0 0.00025 20.9 0.0 1.9 1 1 0 1 1 1 1 Trypsin Tricorn_PDZ PF14685.6 KSA04020.1 - 0.00015 21.7 0.2 1.5 8.9 0.0 4.0 4 0 0 4 4 4 1 Tricorn protease PDZ domain PDZ_3 PF17815.1 KSA04020.1 - 0.0035 17.2 0.2 6.6 6.6 0.0 3.3 4 0 0 4 4 4 2 PDZ domain Peptidase_S7 PF00949.21 KSA04020.1 - 0.0042 16.9 0.1 0.011 15.5 0.1 1.7 1 0 0 1 1 1 1 Peptidase S7, Flavivirus NS3 serine protease DUF31 PF01732.16 KSA04020.1 - 0.0042 16.7 0.1 0.0077 15.8 0.1 1.4 1 0 0 1 1 1 1 Putative peptidase (DUF31) Peptidase_S46 PF10459.9 KSA04020.1 - 0.0078 14.9 0.1 0.1 11.2 0.0 2.0 2 0 0 2 2 2 1 Peptidase S46 Peptidase_S29 PF02907.15 KSA04020.1 - 0.076 12.8 0.0 0.26 11.0 0.0 1.8 2 0 0 2 2 2 0 Hepatitis C virus NS3 protease ORC6 PF05460.13 KSA04021.1 - 7.2e-108 361.0 0.9 8.4e-108 360.8 0.9 1.0 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) ETC_C1_NDUFA4 PF04800.12 KSA04022.1 - 7.6e-32 109.4 1.4 1.1e-31 109.0 1.4 1.1 1 0 0 1 1 1 1 ETC complex I subunit conserved region N-SET PF11764.8 KSA04023.1 - 4.8e-54 183.0 3.6 4.8e-54 183.0 3.6 3.4 3 0 0 3 3 3 1 COMPASS (Complex proteins associated with Set1p) component N SET_assoc PF11767.8 KSA04023.1 - 3e-26 90.8 2.1 8.1e-26 89.5 2.1 1.8 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated SET PF00856.28 KSA04023.1 - 1.3e-18 67.9 0.2 1.3e-18 67.9 0.2 4.1 2 2 0 3 3 3 1 SET domain RRM_1 PF00076.22 KSA04023.1 - 0.011 15.6 0.1 0.13 12.1 0.0 2.6 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MutS_V PF00488.21 KSA04024.1 - 1.2e-67 227.6 0.0 2.2e-67 226.8 0.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KSA04024.1 - 5.9e-29 101.6 7.9 2.5e-28 99.6 6.3 2.7 2 1 0 2 2 2 1 MutS domain III MutS_I PF01624.20 KSA04024.1 - 1.6e-22 79.8 0.0 3.4e-21 75.6 0.0 2.9 3 0 0 3 3 3 1 MutS domain I MutS_II PF05188.17 KSA04024.1 - 4e-13 49.8 2.4 2.5e-11 44.0 0.0 3.3 3 1 0 3 3 3 1 MutS domain II HAS-barrel PF09378.10 KSA04024.1 - 0.018 15.2 0.2 2 8.6 0.1 3.4 3 0 0 3 3 3 0 HAS barrel domain DUF4250 PF14056.6 KSA04024.1 - 0.14 12.2 1.4 0.4 10.7 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4250) Gar1 PF04410.14 KSA04025.1 - 1.4e-45 154.9 1.3 1.4e-45 154.9 1.3 3.4 2 1 0 2 2 2 1 Gar1/Naf1 RNA binding region SUN PF03856.13 KSA04026.1 - 5.9e-99 330.5 15.4 8.5e-99 330.0 15.4 1.2 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) Macoilin PF09726.9 KSA04026.1 - 0.00079 18.1 6.2 0.00085 18.0 6.2 1.1 1 0 0 1 1 1 1 Macoilin family SPX PF03105.19 KSA04026.1 - 0.083 12.8 3.9 0.089 12.7 3.9 1.1 1 0 0 1 1 1 0 SPX domain Apt1 PF10351.9 KSA04026.1 - 3 6.6 10.5 4.1 6.1 10.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF1635 PF07795.11 KSA04026.1 - 5.7 6.7 6.5 11 5.8 6.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Miga PF10265.9 KSA04026.1 - 8 5.3 6.9 11 4.9 6.9 1.1 1 0 0 1 1 1 0 Mitoguardin Sugar_tr PF00083.24 KSA04028.1 - 2.5e-88 296.9 24.7 3.1e-88 296.6 24.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KSA04028.1 - 1.6e-21 76.6 21.2 1.6e-21 76.6 21.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KSA04028.1 - 2.1e-07 29.9 16.1 0.00024 19.8 3.7 2.6 2 1 0 2 2 2 2 MFS/sugar transport protein Csm1_N PF18504.1 KSA04028.1 - 0.25 11.7 2.0 0.24 11.8 0.6 1.7 2 0 0 2 2 2 0 Csm1 N-terminal domain Alpha-amylase PF00128.24 KSA04029.1 - 9.3e-112 373.9 3.2 1.5e-111 373.3 3.2 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 KSA04029.1 - 4.7e-06 26.6 0.0 1e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain hDGE_amylase PF14701.6 KSA04029.1 - 0.0082 15.3 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain Alpha-amylase_C PF02806.18 KSA04029.1 - 0.012 16.0 0.0 0.035 14.6 0.0 1.7 1 0 0 1 1 1 0 Alpha amylase, C-terminal all-beta domain AA_permease PF00324.21 KSA04030.1 - 5.7e-128 427.5 47.7 6.9e-128 427.2 47.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KSA04030.1 - 1.9e-28 99.5 52.4 2.5e-28 99.1 51.9 1.4 1 1 0 1 1 1 1 Amino acid permease Eaf7 PF07904.13 KSA04031.1 - 1.1e-13 51.4 22.1 7.8e-12 45.5 22.1 3.1 1 1 0 1 1 1 1 Chromatin modification-related protein EAF7 DUF573 PF04504.14 KSA04031.1 - 0.0064 17.1 0.1 0.032 14.9 0.1 2.2 1 1 0 1 1 1 1 Protein of unknown function, DUF573 S4 PF01479.25 KSA04032.1 - 4e-16 58.5 0.0 8.8e-16 57.4 0.0 1.6 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.6 KSA04032.1 - 0.044 13.6 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 S4 domain She9_MDM33 PF05546.11 KSA04033.1 - 1.6e-86 289.2 7.7 1.6e-86 289.2 7.7 2.2 2 0 0 2 2 2 1 She9 / Mdm33 family RPW8 PF05659.11 KSA04033.1 - 0.018 14.8 1.9 0.018 14.8 1.9 2.3 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 TERB2 PF15101.6 KSA04033.1 - 0.14 12.2 9.6 13 5.7 8.6 3.0 2 1 1 3 3 3 0 Telomere-associated protein TERB2 Curto_V2 PF07325.11 KSA04033.1 - 4 7.3 7.7 15 5.5 6.1 2.4 2 1 0 2 2 2 0 Curtovirus V2 protein PI-PLC-X PF00388.19 KSA04034.1 - 2.8e-19 69.1 0.0 1.1e-18 67.3 0.0 1.8 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain Sugar_tr PF00083.24 KSA04035.1 - 2.5e-74 250.8 15.0 4.1e-73 246.8 15.0 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KSA04035.1 - 2.7e-23 82.5 21.6 1.8e-16 60.0 3.9 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KSA04035.1 - 0.0026 17.1 5.6 0.0037 16.6 4.3 1.8 1 1 1 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF3980 PF13140.6 KSA04035.1 - 7.9 7.0 9.6 0.3 11.6 1.0 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF3980) DNA_ligase_A_M PF01068.21 KSA04036.1 - 2.8e-55 187.1 0.3 6.5e-55 185.9 0.3 1.7 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KSA04036.1 - 4.3e-25 89.0 0.1 1.1e-24 87.7 0.1 1.8 1 0 0 1 1 1 1 DNA ligase N terminus BRCT_2 PF16589.5 KSA04036.1 - 8.5e-19 67.8 1.6 2.5e-08 34.2 0.1 2.9 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain RNA_ligase PF09414.10 KSA04036.1 - 6.7e-10 39.5 0.2 1.4e-09 38.5 0.2 1.6 1 0 0 1 1 1 1 RNA ligase BRCT PF00533.26 KSA04036.1 - 3e-09 37.1 3.0 0.0002 21.7 0.5 2.9 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain DNA_ligase_A_C PF04679.15 KSA04036.1 - 1.2e-07 32.3 0.0 2.4e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region mRNA_cap_enzyme PF01331.19 KSA04036.1 - 2.3e-05 24.3 1.3 0.072 12.9 0.1 2.4 2 0 0 2 2 2 2 mRNA capping enzyme, catalytic domain PH PF00169.29 KSA04037.1 - 0.023 15.2 0.1 0.083 13.4 0.1 2.0 1 0 0 1 1 1 0 PH domain RCR PF12273.8 KSA04037.1 - 0.51 11.0 5.2 1.1 10.0 0.9 2.4 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red Ribonuc_red_sm PF00268.21 KSA04038.1 - 1.8e-120 401.6 1.1 2.8e-120 401.0 1.1 1.3 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain KASH_CCD PF14662.6 KSA04038.1 - 0.0027 17.6 2.2 0.0036 17.1 2.2 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH DUF4744 PF15918.5 KSA04038.1 - 0.12 13.2 0.9 0.34 11.8 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4744) Ribo_biogen_C PF04034.13 KSA04039.1 - 3e-52 175.7 0.0 4.3e-52 175.2 0.0 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 KSA04039.1 - 2.3e-16 59.3 0.4 4.5e-16 58.4 0.4 1.5 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI RRN3 PF05327.11 KSA04039.1 - 2.9 6.3 13.2 4.2 5.8 13.2 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 NARP1 PF12569.8 KSA04039.1 - 8.4 5.2 10.0 1.6 7.5 1.0 2.1 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 Hydantoinase_B PF02538.14 KSA04040.1 - 1.6e-205 683.4 0.1 2e-205 683.1 0.1 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 KSA04040.1 - 5.7e-94 314.6 0.0 9.1e-94 314.0 0.0 1.3 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KSA04040.1 - 8.8e-54 181.9 0.0 5.4e-52 176.1 0.0 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region VPS9 PF02204.18 KSA04041.1 - 4.6e-14 52.5 0.8 1.8e-13 50.6 0.8 2.1 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_5 PF13857.6 KSA04041.1 - 7.2e-09 35.7 0.4 0.0011 19.2 0.1 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KSA04041.1 - 0.00076 20.0 8.9 0.0041 17.7 0.3 3.5 1 1 2 3 3 3 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KSA04041.1 - 0.038 14.5 0.5 7.3 7.5 0.0 4.4 4 0 0 4 4 4 0 Ankyrin repeat SGTA_dimer PF16546.5 KSA04042.1 - 1.1e-26 92.4 1.3 2.2e-26 91.4 1.3 1.5 1 0 0 1 1 1 1 Homodimerisation domain of SGTA TPR_1 PF00515.28 KSA04042.1 - 4.7e-16 57.8 4.3 4.3e-07 29.5 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KSA04042.1 - 3.4e-15 54.8 4.4 0.00046 20.1 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 KSA04042.1 - 1.4e-10 40.6 4.9 0.00063 19.4 0.1 3.3 1 1 2 3 3 3 3 TPR repeat TPR_17 PF13431.6 KSA04042.1 - 1e-08 34.9 1.7 0.0031 17.8 0.1 3.6 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 KSA04042.1 - 2.1e-08 33.7 11.9 0.0022 18.1 0.6 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KSA04042.1 - 1.6e-05 25.1 6.0 0.0053 17.0 1.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 KSA04042.1 - 1.7e-05 25.3 3.7 0.77 10.7 0.2 4.0 2 1 2 4 4 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KSA04042.1 - 5.8e-05 23.7 2.3 0.023 15.3 0.1 2.5 1 1 0 2 2 2 1 Tetratricopeptide repeat STI1 PF17830.1 KSA04042.1 - 0.00063 19.6 10.6 0.0012 18.8 8.1 2.2 2 0 0 2 2 2 1 STI1 domain TPR_7 PF13176.6 KSA04042.1 - 0.00066 19.5 0.5 13 6.0 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 KSA04042.1 - 0.00088 19.7 1.3 0.045 14.3 0.6 2.8 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 KSA04042.1 - 0.0014 18.5 7.8 0.099 12.6 0.4 3.4 4 0 0 4 4 3 2 Tetratricopeptide repeat BTAD PF03704.17 KSA04042.1 - 0.0029 18.0 2.4 0.0094 16.4 0.2 2.4 1 1 2 3 3 3 1 Bacterial transcriptional activator domain TPR_15 PF13429.6 KSA04042.1 - 0.0071 15.6 1.2 0.035 13.3 0.3 2.0 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 KSA04042.1 - 0.028 14.6 0.0 0.066 13.4 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 KSA04042.1 - 0.049 13.1 0.5 3.4 7.2 0.0 2.4 2 0 0 2 2 2 0 SHNi-TPR TPR_6 PF13174.6 KSA04042.1 - 0.072 13.8 6.0 1.4 9.7 1.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF5633 PF18656.1 KSA04042.1 - 0.35 10.8 3.1 12 5.9 0.2 3.3 3 0 0 3 3 3 0 Family of unknown function (DUF5633) T3SS_needle_F PF09392.10 KSA04042.1 - 1.3 9.3 9.3 0.3 11.3 0.7 3.6 4 0 0 4 4 4 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF MIT PF04212.18 KSA04042.1 - 2.3 8.4 7.1 0.83 9.8 0.1 3.2 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain CENP-X PF09415.10 KSA04043.1 - 8e-23 80.6 3.4 4.1e-21 75.1 3.4 2.2 1 1 0 1 1 1 1 CENP-S associating Centromere protein X CBFD_NFYB_HMF PF00808.23 KSA04043.1 - 0.021 15.1 0.0 0.051 13.9 0.0 1.7 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Dynactin_p62 PF05502.13 KSA04044.1 - 1.7e-11 43.6 26.2 1e-05 24.6 20.1 2.3 1 1 0 2 2 2 2 Dynactin p62 family DUF1360 PF07098.11 KSA04044.1 - 0.16 11.9 1.2 0.47 10.4 1.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1360) His_Phos_1 PF00300.22 KSA04045.1 - 3e-06 27.1 0.0 1.2e-05 25.1 0.0 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) eIF3_subunit PF08597.10 KSA04046.1 - 1.3e-59 202.0 24.2 1.5e-59 201.8 24.2 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit GAT PF03127.14 KSA04047.1 - 0.077 13.3 2.6 1.1 9.6 0.1 3.3 3 1 1 4 4 4 0 GAT domain Thioredoxin PF00085.20 KSA04048.1 - 1.5e-30 105.2 0.0 1.7e-30 105.0 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KSA04048.1 - 2.9e-07 30.7 0.1 3.8e-05 23.9 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 KSA04048.1 - 1.1e-06 29.0 0.3 4.8e-06 27.0 0.3 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 KSA04048.1 - 1e-05 25.3 0.0 1.2e-05 25.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin HyaE PF07449.11 KSA04048.1 - 0.00017 21.5 0.0 0.00026 20.9 0.0 1.2 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE Glutaredoxin PF00462.24 KSA04048.1 - 0.00026 21.2 0.1 0.00042 20.5 0.1 1.3 1 0 0 1 1 1 1 Glutaredoxin Phosducin PF02114.16 KSA04048.1 - 0.0006 18.8 0.0 0.00063 18.8 0.0 1.0 1 0 0 1 1 1 1 Phosducin AhpC-TSA PF00578.21 KSA04048.1 - 0.00096 19.1 0.1 0.0021 18.0 0.1 1.6 1 1 0 1 1 1 1 AhpC/TSA family OST3_OST6 PF04756.13 KSA04048.1 - 0.0013 18.1 0.0 0.0014 18.1 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family DIM1 PF02966.16 KSA04048.1 - 0.0054 16.5 0.0 0.0069 16.2 0.0 1.2 1 0 0 1 1 1 1 Mitosis protein DIM1 Redoxin PF08534.10 KSA04048.1 - 0.0059 16.3 0.1 0.01 15.5 0.0 1.4 1 1 0 1 1 1 1 Redoxin TraF PF13728.6 KSA04048.1 - 0.0073 16.2 0.0 0.0086 15.9 0.0 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein PCYCGC PF13798.6 KSA04048.1 - 0.099 12.5 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function with PCYCGC motif Thioredoxin_7 PF13899.6 KSA04048.1 - 0.11 12.7 0.2 0.22 11.7 0.2 1.6 1 1 0 1 1 1 0 Thioredoxin-like Y_phosphatase PF00102.27 KSA04049.1 - 2.2e-55 187.8 0.0 3.9e-55 187.0 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.20 KSA04049.1 - 2.6e-07 31.1 0.0 1.3e-06 28.8 0.0 2.3 1 1 0 1 1 1 1 Rhodanese-like domain DSPc PF00782.20 KSA04049.1 - 0.027 14.3 1.3 0.28 11.0 0.0 3.2 3 0 0 3 3 3 0 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KSA04049.1 - 0.03 14.3 0.0 0.071 13.1 0.0 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family Presenilin PF01080.17 KSA04050.1 - 7 5.3 5.0 12 4.5 5.0 1.4 1 0 0 1 1 1 0 Presenilin DHHW PF14286.6 KSA04051.1 - 0.022 14.1 2.2 0.028 13.8 2.2 1.1 1 0 0 1 1 1 0 DHHW protein Mitofilin PF09731.9 KSA04051.1 - 1.2 7.9 18.6 1.4 7.7 18.6 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Hid1 PF12722.7 KSA04051.1 - 4.4 5.3 10.7 4.9 5.2 10.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein YL1 PF05764.13 KSA04051.1 - 6 6.9 22.9 7.1 6.7 22.9 1.2 1 0 0 1 1 1 0 YL1 nuclear protein TRAPP PF04051.16 KSA04052.1 - 7.1e-45 152.3 0.0 9.2e-45 151.9 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Acetyltransf_1 PF00583.25 KSA04053.1 - 7.9e-15 55.1 0.0 1.1e-14 54.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KSA04053.1 - 1.8e-09 37.6 0.0 2.4e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KSA04053.1 - 1.1e-05 25.3 0.0 1.9e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 KSA04053.1 - 1.2e-05 25.7 0.0 1.8e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KSA04053.1 - 0.00032 20.8 0.1 0.00071 19.6 0.1 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 KSA04053.1 - 0.002 17.7 1.0 0.0056 16.2 0.3 1.8 2 0 0 2 2 2 1 Putative acetyl-transferase Acetyltransf_3 PF13302.7 KSA04053.1 - 0.0053 17.4 0.0 0.0084 16.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KSA04053.1 - 0.059 13.5 0.0 0.17 12.0 0.0 1.9 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase Acetyltransf_13 PF13880.6 KSA04053.1 - 0.11 12.5 0.1 0.19 11.7 0.1 1.3 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase KH_8 PF17903.1 KSA04054.1 - 4.3e-07 29.9 0.0 8.4e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 KSA04054.1 - 0.051 13.4 0.3 0.13 12.1 0.3 1.6 1 0 0 1 1 1 0 KH domain MDM31_MDM32 PF08118.11 KSA04055.1 - 3.4e-111 372.5 11.4 3e-109 366.1 11.4 2.2 1 1 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins G-patch_2 PF12656.7 KSA04056.1 - 2e-18 66.2 0.1 2e-18 66.2 0.1 2.2 3 0 0 3 3 3 1 G-patch domain TFIID-18kDa PF02269.16 KSA04058.1 - 2.3e-33 114.1 1.4 2e-32 111.0 0.1 2.6 3 0 0 3 3 3 1 Transcription initiation factor IID, 18kD subunit TAFII28 PF04719.14 KSA04058.1 - 0.057 13.5 0.1 0.15 12.2 0.1 1.7 1 1 0 1 1 1 0 hTAFII28-like protein conserved region DUF4788 PF16032.5 KSA04058.1 - 0.13 11.2 1.4 5.6 5.8 0.0 2.9 3 1 1 4 4 4 0 Domain of unknown function (DUF4788) Syntaxin-6_N PF09177.11 KSA04059.1 - 5.3e-12 46.2 6.3 2.4e-11 44.0 2.7 2.7 2 1 0 2 2 2 1 Syntaxin 6, N-terminal Use1 PF09753.9 KSA04059.1 - 0.0067 16.2 8.4 0.0087 15.8 8.4 1.1 1 0 0 1 1 1 1 Membrane fusion protein Use1 SNARE PF05739.19 KSA04059.1 - 0.01 15.8 1.5 0.027 14.5 1.5 1.7 1 0 0 1 1 1 0 SNARE domain WXG100 PF06013.12 KSA04059.1 - 0.038 14.2 8.7 9.8 6.5 0.1 3.6 3 1 0 3 3 3 0 Proteins of 100 residues with WXG Sec20 PF03908.13 KSA04059.1 - 0.15 12.0 5.3 4.3 7.3 0.3 2.6 2 1 0 2 2 2 0 Sec20 DASH_Dad3 PF08656.10 KSA04059.1 - 1.1 9.3 6.0 6.7 6.9 2.1 3.2 3 1 0 3 3 3 0 DASH complex subunit Dad3 DUF16 PF01519.16 KSA04059.1 - 1.4 9.4 16.7 0.25 11.8 4.2 2.3 1 1 1 2 2 2 0 Protein of unknown function DUF16 ACCA PF03255.14 KSA04059.1 - 1.9 8.3 9.1 1.2 9.0 0.2 2.7 1 1 2 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit BST2 PF16716.5 KSA04059.1 - 2.4 8.8 14.0 3.7 8.2 3.0 3.1 1 1 0 2 2 2 0 Bone marrow stromal antigen 2 V_ATPase_I PF01496.19 KSA04059.1 - 4.7 5.0 13.4 0.17 9.8 5.5 1.7 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family TBCA PF02970.16 KSA04059.1 - 8.6 6.8 8.4 0.73 10.2 0.2 2.9 1 1 2 3 3 3 0 Tubulin binding cofactor A Dpy-30 PF05186.13 KSA04060.1 - 9.5e-14 50.8 0.0 1.3e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 Dpy-30 motif Mito_carr PF00153.27 KSA04061.1 - 1.7e-12 47.1 0.1 0.00027 20.8 0.0 3.7 3 1 0 3 3 3 2 Mitochondrial carrier protein Vps5 PF09325.10 KSA04062.1 - 3.5e-08 33.3 8.5 9.2e-08 31.9 8.0 1.9 1 1 1 2 2 2 1 Vps5 C terminal like PX PF00787.24 KSA04062.1 - 1.4e-05 25.0 1.9 1.9e-05 24.6 0.3 2.2 2 1 0 2 2 2 1 PX domain Sod_Fe_C PF02777.18 KSA04063.1 - 1.8e-33 114.8 0.7 1.8e-33 114.8 0.7 1.6 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KSA04063.1 - 3.6e-29 101.1 2.0 6.1e-29 100.3 2.0 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain HHH_2 PF12826.7 KSA04063.1 - 0.013 15.6 0.0 0.024 14.7 0.0 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix motif Snf7 PF03357.21 KSA04064.1 - 1.3e-12 47.7 15.4 1.6e-12 47.3 15.4 1.2 1 0 0 1 1 1 1 Snf7 GCH_III PF05165.12 KSA04064.1 - 0.017 14.4 3.9 0.027 13.8 3.8 1.4 1 1 0 1 1 1 0 GTP cyclohydrolase III GrpE PF01025.19 KSA04064.1 - 1.2 8.7 11.3 0.16 11.6 5.4 2.0 1 1 1 2 2 2 0 GrpE DUF3886 PF13025.6 KSA04064.1 - 1.8 8.8 10.4 0.32 11.2 5.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3886) TPR_2 PF07719.17 KSA04065.1 - 3.9e-07 29.7 0.4 0.046 13.8 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 KSA04065.1 - 2.7e-06 27.6 0.9 0.00048 20.4 0.4 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 KSA04065.1 - 0.00025 20.7 4.2 0.025 14.4 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 KSA04065.1 - 0.00068 19.3 0.1 0.063 13.0 0.0 2.6 2 0 0 2 2 2 1 TPR repeat TPR_9 PF13371.6 KSA04065.1 - 0.048 13.8 0.3 0.21 11.8 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 KSA04065.1 - 0.05 13.8 0.5 17 5.9 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 KSA04065.1 - 0.095 12.2 0.1 0.79 9.2 0.0 2.4 2 0 0 2 2 2 0 SHNi-TPR Cid2 PF09774.9 KSA04066.1 - 1.9e-36 125.9 7.9 4.7e-36 124.6 7.9 1.6 1 1 0 1 1 1 1 Caffeine-induced death protein 2 NGF PF00243.18 KSA04066.1 - 0.0037 17.5 0.3 0.0037 17.5 0.3 1.7 2 1 0 2 2 2 1 Nerve growth factor family CREPT PF16566.5 KSA04066.1 - 0.036 14.2 0.3 0.11 12.7 0.1 1.8 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Pkinase PF00069.25 KSA04067.1 - 1.8e-63 214.4 0.0 1.8e-63 214.4 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KSA04067.1 - 4.5e-32 111.4 1.0 1e-28 100.4 0.0 2.6 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KSA04067.1 - 0.0045 16.3 0.2 0.098 12.0 0.0 2.8 2 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KSA04067.1 - 0.0051 15.8 0.2 0.0051 15.8 0.2 1.9 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 KSA04067.1 - 0.068 12.5 0.0 0.2 11.0 0.0 1.7 1 1 1 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Peptidase_M3 PF01432.20 KSA04068.1 - 4.9e-109 365.6 0.1 6.6e-109 365.2 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M3 Glyco_hydro_59 PF02057.15 KSA04068.1 - 0.065 12.5 0.5 0.31 10.2 0.1 2.1 2 0 0 2 2 2 0 Glycosyl hydrolase family 59 Imm30 PF15565.6 KSA04069.1 - 0.0084 16.2 1.0 0.0084 16.2 1.0 4.0 4 0 0 4 4 4 1 Immunity protein 30 DUF1664 PF07889.12 KSA04069.1 - 9.6 6.3 28.1 0.72 9.9 1.1 4.8 2 2 2 4 4 4 0 Protein of unknown function (DUF1664) tRNA-synt_2b PF00587.25 KSA04070.1 - 1.8e-24 86.7 0.0 3.7e-24 85.7 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 KSA04070.1 - 0.00021 21.5 8.6 0.00037 20.7 8.6 1.4 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain APG6_N PF17675.1 KSA04070.1 - 0.084 13.4 5.3 0.21 12.1 5.3 1.6 1 0 0 1 1 1 0 Apg6 coiled-coil region FlaC_arch PF05377.11 KSA04070.1 - 7.3 7.1 7.5 1.7 9.1 0.7 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) AA_permease PF00324.21 KSA04071.1 - 3.6e-121 405.1 29.3 4.4e-121 404.8 29.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KSA04071.1 - 1.5e-29 103.1 30.9 2e-29 102.7 30.9 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4781 PF16013.5 KSA04071.1 - 1 8.1 3.8 0.38 9.5 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4781) Lgl_C PF08596.10 KSA04072.1 - 7.9e-135 449.5 1.0 1.2e-134 448.9 1.0 1.3 1 0 0 1 1 1 1 Lethal giant larvae(Lgl) like, C-terminal ANAPC4_WD40 PF12894.7 KSA04072.1 - 3e-07 30.6 0.1 0.028 14.7 0.0 6.3 8 1 1 9 9 9 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KSA04072.1 - 4.6e-05 24.1 0.1 2.4 9.2 0.0 4.6 4 0 0 4 4 4 2 WD domain, G-beta repeat DPM2 PF07297.12 KSA04073.1 - 6.4e-28 96.9 0.7 7.5e-28 96.6 0.7 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) Adap_comp_sub PF00928.21 KSA04074.1 - 3.2e-44 151.3 0.9 2.4e-36 125.4 0.0 2.2 2 0 0 2 2 2 2 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KSA04074.1 - 0.04 13.8 0.2 0.075 13.0 0.2 1.4 1 0 0 1 1 1 0 Clathrin adaptor complex small chain Cu-oxidase_2 PF07731.14 KSA04075.1 - 8.9e-48 161.5 3.1 7.2e-42 142.4 0.2 3.0 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KSA04075.1 - 2.7e-41 140.3 0.2 7.6e-38 129.2 0.1 2.9 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 KSA04075.1 - 1.2e-35 123.0 4.3 6.2e-32 110.9 0.9 3.3 3 1 0 3 3 3 2 Multicopper oxidase DHDPS PF00701.22 KSA04076.1 - 7e-45 153.0 0.0 8.2e-45 152.7 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family ARTD15_N PF18084.1 KSA04076.1 - 0.13 12.5 0.0 23 5.3 0.0 3.0 2 1 1 3 3 3 0 ARTD15 N-terminal domain Abhydrolase_1 PF00561.20 KSA04077.1 - 8.4e-17 61.7 0.0 1.5e-16 60.8 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KSA04077.1 - 2.6e-12 47.8 0.0 3.4e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KSA04077.1 - 8e-08 31.8 0.0 3.6e-07 29.7 0.0 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 KSA04077.1 - 0.0082 16.0 0.0 0.55 10.1 0.0 2.2 1 1 0 2 2 2 1 alpha/beta hydrolase fold LIDHydrolase PF10230.9 KSA04077.1 - 0.057 13.0 0.0 0.13 11.8 0.0 1.7 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase Ndr PF03096.14 KSA04077.1 - 0.089 11.5 0.0 0.18 10.5 0.0 1.5 1 1 0 1 1 1 0 Ndr family Lipase_3 PF01764.25 KSA04077.1 - 0.13 12.2 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF3530 PF12048.8 KSA04077.1 - 0.14 11.5 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) ThiF PF00899.21 KSA04078.1 - 6.7e-66 222.1 0.0 9.8e-66 221.6 0.0 1.1 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 KSA04078.1 - 4e-25 87.8 0.8 6.1e-25 87.2 0.8 1.3 1 0 0 1 1 1 1 E2 binding domain Shikimate_DH PF01488.20 KSA04078.1 - 0.0039 17.3 0.1 0.012 15.6 0.0 1.9 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase PglD_N PF17836.1 KSA04078.1 - 0.04 14.5 1.4 0.75 10.5 0.3 2.5 1 1 1 2 2 2 0 PglD N-terminal domain Ecm33 PF12454.8 KSA04078.1 - 0.07 13.3 1.0 0.07 13.3 1.0 1.8 2 0 0 2 2 2 0 GPI-anchored cell wall organization protein UAE_UbL PF14732.6 KSA04078.1 - 0.12 13.0 0.0 0.24 12.0 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain 2-Hacid_dh_C PF02826.19 KSA04078.1 - 0.16 11.4 0.0 1.4 8.2 0.0 2.1 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Rad52_Rad22 PF04098.15 KSA04079.1 - 2.1e-57 193.4 0.0 4.3e-57 192.3 0.0 1.5 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein DUF3511 PF12023.8 KSA04080.1 - 0.037 13.8 0.2 5.3 6.9 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3511) LSM PF01423.22 KSA04081.1 - 5.1e-16 58.1 0.1 6.3e-16 57.8 0.1 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 KSA04081.1 - 0.0017 17.9 0.1 0.0029 17.2 0.1 1.4 1 0 0 1 1 1 1 Hfq protein ERCC4 PF02732.15 KSA04082.1 - 2.9e-24 86.1 0.7 8.5e-24 84.5 0.7 1.9 1 0 0 1 1 1 1 ERCC4 domain EntA_Immun PF08951.10 KSA04082.1 - 0.037 14.4 0.3 29 5.1 0.0 4.3 4 0 0 4 4 4 0 Enterocin A Immunity Ndc1_Nup PF09531.10 KSA04084.1 - 1.5e-128 430.2 17.1 1.7e-128 430.0 17.1 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Na_H_Exchanger PF00999.21 KSA04085.1 - 5.8e-69 232.7 39.2 7.6e-69 232.3 39.2 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Myc_target_1 PF15179.6 KSA04085.1 - 0.33 10.8 4.5 0.16 11.9 0.5 2.4 3 0 0 3 3 3 0 Myc target protein 1 Wzy_C PF04932.15 KSA04085.1 - 2.4 7.8 0.0 2.4 7.8 0.0 4.0 3 2 0 3 3 3 0 O-Antigen ligase TPT PF03151.16 KSA04086.1 - 4.1e-37 128.1 17.0 1e-36 126.8 17.0 1.6 1 1 0 1 1 1 1 Triose-phosphate Transporter family DUF2834 PF11196.8 KSA04086.1 - 0.039 14.3 0.0 0.039 14.3 0.0 3.3 5 0 0 5 5 5 0 Protein of unknown function (DUF2834) EamA PF00892.20 KSA04086.1 - 0.1 12.8 24.4 0.17 12.1 9.5 3.1 2 2 0 2 2 2 0 EamA-like transporter family Mito_carr PF00153.27 KSA04087.1 - 6.9e-29 99.6 5.3 5.7e-14 51.8 0.0 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein FA_desaturase PF00487.24 KSA04088.1 - 2.4e-24 86.6 20.2 4.2e-24 85.8 20.2 1.3 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 KSA04088.1 - 0.00024 21.3 0.0 0.00047 20.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) TMEM213 PF15192.6 KSA04088.1 - 0.028 14.4 0.2 0.15 12.1 0.2 2.2 2 0 0 2 2 2 0 TMEM213 family ICMT PF04140.14 KSA04089.1 - 4.5e-23 81.5 1.1 6.8e-23 80.9 1.1 1.3 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KSA04089.1 - 1.7e-14 54.1 2.6 2.2e-14 53.7 2.6 1.2 1 0 0 1 1 1 1 Phospholipid methyltransferase DUF1295 PF06966.12 KSA04089.1 - 3.7e-06 26.6 1.5 4.5e-06 26.4 1.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) NnrU PF07298.11 KSA04089.1 - 0.0093 15.5 0.2 0.01 15.4 0.2 1.2 1 0 0 1 1 1 1 NnrU protein P21-Arc PF04062.14 KSA04090.1 - 2.2e-77 259.0 0.0 2.5e-77 258.8 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit CNH PF00780.22 KSA04091.1 - 7.7e-72 242.2 0.0 1.2e-71 241.5 0.0 1.3 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 KSA04091.1 - 1.9e-36 126.0 0.2 1.9e-36 126.0 0.2 2.6 3 1 0 3 3 3 1 RhoGEF domain PH_5 PF15405.6 KSA04091.1 - 2.1e-27 95.9 0.7 9.9e-27 93.7 0.7 2.3 1 0 0 1 1 1 1 Pleckstrin homology domain DEP PF00610.21 KSA04091.1 - 5.7e-12 45.5 0.0 1.3e-11 44.3 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) ELO PF01151.18 KSA04092.1 - 1.5e-57 195.0 28.8 1.8e-57 194.7 28.8 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family zf-C2H2_6 PF13912.6 KSA04093.1 - 8e-05 22.5 14.4 0.00019 21.3 1.5 4.4 3 1 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_4 PF13894.6 KSA04093.1 - 0.00039 21.0 31.8 0.15 13.0 3.4 5.2 4 1 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.26 KSA04093.1 - 0.019 15.4 4.6 0.019 15.4 4.6 5.6 6 1 0 6 6 6 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KSA04093.1 - 0.036 14.4 8.0 0.21 11.9 0.1 4.4 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding 4HBT_2 PF13279.6 KSA04094.1 - 4e-08 33.8 0.1 5.6e-08 33.3 0.1 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily HECT PF00632.25 KSA04095.1 - 1.2e-92 310.7 1.1 2.6e-92 309.6 0.1 2.1 3 0 0 3 3 3 1 HECT-domain (ubiquitin-transferase) DUF908 PF06012.12 KSA04095.1 - 1.4e-86 291.1 0.9 3.4e-86 289.9 0.9 1.7 1 0 0 1 1 1 1 Domain of Unknown Function (DUF908) DUF913 PF06025.12 KSA04095.1 - 1.3e-60 205.3 0.0 1.3e-60 205.3 0.0 3.4 3 1 0 3 3 3 1 Domain of Unknown Function (DUF913) UBM PF14377.6 KSA04095.1 - 2.2e-18 65.0 8.4 7.8e-09 34.7 0.5 2.8 2 0 0 2 2 2 2 Ubiquitin binding region PRP3 PF08572.10 KSA04096.1 - 2.1e-71 240.2 10.2 2.1e-71 240.2 10.2 1.7 2 0 0 2 2 2 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 KSA04096.1 - 3.2e-41 140.8 0.0 3.2e-41 140.8 0.0 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF1115) Ribonuc_red_lgC PF02867.15 KSA04097.1 - 1.7e-189 630.7 0.0 2.2e-189 630.4 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 KSA04097.1 - 2.3e-22 78.8 0.1 7e-22 77.2 0.0 1.9 2 0 0 2 2 2 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 KSA04097.1 - 2e-15 57.1 0.3 7.6e-15 55.2 0.0 2.2 2 0 0 2 2 2 1 ATP cone domain LCCL PF03815.19 KSA04098.1 - 7.1e-07 29.3 0.1 1.7e-06 28.1 0.1 1.6 1 0 0 1 1 1 1 LCCL domain DDHD PF02862.17 KSA04099.1 - 1.3e-48 166.1 0.6 1e-47 163.2 0.0 2.3 2 0 0 2 2 2 1 DDHD domain LIDHydrolase PF10230.9 KSA04099.1 - 0.047 13.3 0.0 0.39 10.2 0.0 2.2 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase WWE PF02825.20 KSA04099.1 - 0.13 12.8 5.7 0.2 12.3 2.1 3.2 2 1 1 3 3 3 0 WWE domain Phlebovirus_NSM PF07246.11 KSA04099.1 - 7.4 5.9 7.0 0.19 11.1 0.1 1.8 2 0 0 2 2 2 0 Phlebovirus nonstructural protein NS-M RNA_Me_trans PF04252.13 KSA04100.1 - 9.3e-77 257.1 0.0 1e-76 257.0 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase Cu_amine_oxid PF01179.20 KSA04101.1 - 1.7e-149 498.2 0.0 2.1e-149 497.9 0.0 1.0 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 KSA04101.1 - 2.1e-15 56.9 0.0 4.2e-15 56.0 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Hat1_N PF10394.9 KSA04101.1 - 0.059 13.6 0.1 0.68 10.1 0.0 2.1 2 0 0 2 2 2 0 Histone acetyl transferase HAT1 N-terminus Cu_amine_oxidN2 PF02727.16 KSA04102.1 - 1.3e-09 38.1 0.1 1.8e-09 37.7 0.1 1.2 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain GTP_EFTU PF00009.27 KSA04104.1 - 8.8e-67 224.4 0.3 1.3e-66 223.9 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 KSA04104.1 - 5.6e-33 113.3 0.0 2e-32 111.5 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 KSA04104.1 - 6e-21 74.3 0.0 1.9e-20 72.7 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KSA04104.1 - 3.1e-13 49.9 0.2 1.2e-12 48.0 0.1 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.6 KSA04104.1 - 8.2e-13 48.3 0.0 2.7e-12 46.6 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 KSA04104.1 - 0.00012 22.1 0.2 0.00027 21.0 0.2 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Formyl_trans_N PF00551.19 KSA04105.1 - 7.4e-42 143.1 0.3 6.2e-41 140.1 0.3 1.9 1 1 0 1 1 1 1 Formyl transferase Iso_dh PF00180.20 KSA04106.1 - 7.2e-98 327.9 0.0 8.8e-98 327.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase ADH_N PF08240.12 KSA04107.1 - 3e-25 88.2 4.2 7.2e-25 87.0 4.2 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KSA04107.1 - 9e-20 71.0 0.3 1.8e-19 70.0 0.3 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KSA04107.1 - 1.3e-06 28.1 0.1 3.1e-06 26.8 0.1 1.6 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus Sacchrp_dh_NADP PF03435.18 KSA04107.1 - 0.00025 21.3 0.1 0.00043 20.5 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain AlaDh_PNT_C PF01262.21 KSA04107.1 - 0.0028 17.0 0.2 0.005 16.2 0.2 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 KSA04107.1 - 0.011 15.3 0.1 0.021 14.4 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Imm70 PF15601.6 KSA04107.1 - 0.017 14.6 0.0 0.14 11.7 0.0 2.3 2 1 0 2 2 2 0 Immunity protein 70 TrkA_N PF02254.18 KSA04107.1 - 0.053 13.8 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain ADH_zinc_N_2 PF13602.6 KSA04107.1 - 0.068 14.2 0.0 0.16 13.0 0.0 1.6 1 1 0 1 1 1 0 Zinc-binding dehydrogenase NAD_binding_7 PF13241.6 KSA04107.1 - 0.11 12.9 0.1 0.25 11.8 0.1 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Aha1_N PF09229.11 KSA04108.1 - 1.1e-36 126.0 0.8 1.8e-36 125.3 0.8 1.3 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 KSA04108.1 - 4.4e-18 65.7 0.0 6.9e-18 65.1 0.0 1.3 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein DUF1631 PF07793.11 KSA04108.1 - 0.13 10.7 0.6 0.16 10.3 0.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) Proteasome PF00227.26 KSA04109.1 - 9.3e-48 162.2 0.0 1.3e-47 161.8 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 KSA04109.1 - 7.2e-14 50.9 0.7 7.2e-14 50.9 0.7 1.7 2 0 0 2 2 2 1 Proteasome beta subunits C terminal TRAPPC9-Trs120 PF08626.11 KSA04110.1 - 0 1340.8 24.5 0 1340.6 24.5 1.0 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit TPR_12 PF13424.6 KSA04110.1 - 0.0083 16.4 0.1 0.019 15.3 0.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 KSA04110.1 - 0.29 11.0 0.9 0.66 9.9 0.1 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat COX6B PF02297.17 KSA04111.1 - 6.8e-23 80.7 7.1 8.2e-23 80.4 7.1 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb v110 PF01639.17 KSA04111.1 - 0.0047 16.8 0.9 0.0056 16.5 0.9 1.2 1 0 0 1 1 1 1 Viral family 110 MDH PF02315.16 KSA04111.1 - 0.026 14.6 0.8 0.042 13.9 0.5 1.5 1 1 1 2 2 2 0 Methanol dehydrogenase beta subunit Pet191_N PF10203.9 KSA04111.1 - 0.21 11.9 3.1 8 6.8 0.2 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 Asparaginase PF00710.20 KSA04112.1 - 7.1e-59 198.6 0.1 9.9e-59 198.1 0.1 1.2 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 KSA04112.1 - 5e-18 65.4 0.0 1.3e-17 64.0 0.0 1.7 2 0 0 2 2 2 1 Glutaminase/Asparaginase C-terminal domain AMP-binding PF00501.28 KSA04113.1 - 2.5e-87 293.2 0.0 3.7e-87 292.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_5 PF07994.12 KSA04114.1 - 1.3e-145 484.8 0.1 1.5e-145 484.6 0.1 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 KSA04114.1 - 8.6e-44 148.3 0.4 1.8e-43 147.2 0.4 1.6 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Glyco_hydro_18 PF00704.28 KSA04115.1 - 5.8e-25 88.7 4.7 1.5e-24 87.3 4.7 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Tmemb_cc2 PF10267.9 KSA04115.1 - 0.13 11.4 5.8 0.18 10.9 4.7 1.6 2 0 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein CSG2 PF16965.5 KSA04115.1 - 0.19 10.7 0.6 0.27 10.1 0.6 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator MID_MedPIWI PF18296.1 KSA04115.1 - 0.23 11.2 5.7 0.34 10.6 5.7 1.3 1 0 0 1 1 1 0 MID domain of medPIWI Auxin_repressed PF05564.12 KSA04115.1 - 0.46 11.2 8.8 0.83 10.4 8.8 1.4 1 0 0 1 1 1 0 Dormancy/auxin associated protein GTP-bdg_M PF16360.5 KSA04116.1 - 0.073 13.7 0.1 0.091 13.4 0.1 1.2 1 0 0 1 1 1 0 GTP-binding GTPase Middle Region Molybdopterin PF00384.22 KSA04117.1 - 1.7e-68 231.6 0.0 1.2e-34 120.1 0.0 2.2 1 1 1 2 2 2 2 Molybdopterin oxidoreductase Fer2_4 PF13510.6 KSA04117.1 - 4.8e-20 71.4 0.4 1.1e-19 70.2 0.4 1.6 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH_dhqG_C PF09326.11 KSA04117.1 - 2.8e-15 56.7 0.0 6.4e-15 55.6 0.0 1.7 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal NADH-G_4Fe-4S_3 PF10588.9 KSA04117.1 - 6.7e-15 54.3 0.5 6.7e-15 54.3 0.5 2.0 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2 PF00111.27 KSA04117.1 - 8.6e-08 32.0 2.1 1.8e-07 31.0 0.2 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.22 KSA04117.1 - 0.0055 16.4 0.1 0.21 11.3 0.0 2.6 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Lyx_isomer PF07385.12 KSA04117.1 - 0.095 11.9 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 D-lyxose isomerase Fer4 PF00037.27 KSA04117.1 - 0.11 12.4 1.1 3.3 7.7 0.3 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_19 PF06902.11 KSA04117.1 - 0.61 10.2 2.5 11 6.2 2.5 2.6 1 1 0 1 1 1 0 Divergent 4Fe-4S mono-cluster DUF382 PF04037.13 KSA04118.1 - 1.2e-56 190.3 0.4 3.2e-56 188.9 0.4 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF382) PSP PF04046.16 KSA04118.1 - 9.8e-17 60.6 0.5 1.6e-16 59.9 0.5 1.4 1 0 0 1 1 1 1 PSP COG2 PF06148.11 KSA04119.1 - 0.0055 16.8 0.5 0.0075 16.4 0.5 1.2 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 HSBP1 PF06825.12 KSA04119.1 - 0.017 15.0 1.9 0.038 13.8 1.9 1.6 1 1 0 1 1 1 0 Heat shock factor binding protein 1 MtrG PF04210.13 KSA04119.1 - 0.26 11.2 0.5 1.5 8.7 0.3 2.0 1 1 1 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G PRKCSH PF07915.13 KSA04120.1 - 7.2e-15 55.8 1.3 2.1e-14 54.2 0.6 2.2 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein zf-Mss51 PF13824.6 KSA04121.1 - 1.7e-18 66.5 0.4 3e-18 65.6 0.4 1.4 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 YL1_C PF08265.11 KSA04121.1 - 0.057 13.2 0.8 1.8 8.4 0.0 2.6 2 0 0 2 2 2 0 YL1 nuclear protein C-terminal domain ubiquitin PF00240.23 KSA04122.1 - 0.00053 19.7 0.7 0.024 14.4 0.1 3.3 3 1 1 4 4 4 1 Ubiquitin family PI3K_p85B PF02192.16 KSA04122.1 - 0.0078 15.9 0.1 0.94 9.3 0.0 3.5 3 1 0 3 3 3 1 PI3-kinase family, p85-binding domain Flocculin_t3 PF13928.6 KSA04123.1 - 5.7 7.5 19.7 3.8 8.1 14.3 2.7 2 1 0 2 2 2 0 Flocculin type 3 repeat RCC1 PF00415.18 KSA04124.1 - 3.3e-15 56.4 0.0 0.0031 18.1 0.0 4.8 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KSA04124.1 - 2.8e-13 49.3 0.6 7.6e-08 32.0 0.1 3.7 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 KSA04124.1 - 5.6e-12 45.9 0.4 6.7e-07 29.5 0.0 3.8 3 1 1 4 4 4 2 BTB/POZ domain Bromodomain PF00439.25 KSA04125.1 - 1.5e-16 60.3 0.8 9.2e-16 57.7 0.1 2.7 2 0 0 2 2 2 1 Bromodomain Bromo_TP PF07524.13 KSA04125.1 - 1.1e-06 28.5 0.0 3.1e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 Bromodomain associated Bromo_TP_like PF17027.5 KSA04125.1 - 2.1e-05 24.7 0.8 6.7e-05 23.0 0.8 1.9 1 0 0 1 1 1 1 Histone-fold protein Cwf_Cwc_15 PF04889.12 KSA04125.1 - 0.13 12.0 44.0 0.53 10.0 12.1 3.2 3 0 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein UQ_con PF00179.26 KSA04126.1 - 1e-43 148.3 0.1 1.2e-43 148.2 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KSA04126.1 - 0.0019 17.9 0.0 0.0022 17.7 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KSA04126.1 - 0.0029 17.9 0.0 0.0047 17.2 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.13 KSA04126.1 - 0.033 14.0 0.0 0.053 13.4 0.0 1.3 1 0 0 1 1 1 0 UEV domain Fungal_trans_2 PF11951.8 KSA04127.1 - 1.4e-82 277.6 0.7 2e-82 277.0 0.7 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KSA04127.1 - 1.6e-07 31.3 8.5 3e-07 30.5 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.12 KSA04127.1 - 7.4 7.1 9.2 16 6.1 9.2 1.4 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region Nop PF01798.18 KSA04128.1 - 2.6e-86 288.8 0.2 2.6e-86 288.8 0.2 1.9 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 KSA04128.1 - 3.4e-21 75.4 0.9 3.4e-21 75.4 0.9 2.9 3 1 0 3 3 3 1 NOP5NT (NUC127) domain RNA_polI_A34 PF08208.11 KSA04128.1 - 0.052 13.6 42.2 0.081 13.0 42.2 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 EOS1 PF12326.8 KSA04128.1 - 0.23 11.3 1.1 0.33 10.9 1.1 1.4 1 0 0 1 1 1 0 N-glycosylation protein RR_TM4-6 PF06459.12 KSA04128.1 - 1 9.1 22.5 0.9 9.3 21.1 1.6 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 KSA04128.1 - 1.9 6.7 23.3 2.9 6.1 23.3 1.2 1 0 0 1 1 1 0 CDC45-like protein GAGA_bind PF06217.12 KSA04128.1 - 5.3 7.2 17.0 2.2 8.5 14.5 1.7 2 0 0 2 2 2 0 GAGA binding protein-like family SIR2 PF02146.17 KSA04130.1 - 1.8e-38 132.3 0.0 2.6e-36 125.2 0.0 2.7 2 1 0 2 2 2 1 Sir2 family Pkinase PF00069.25 KSA04131.1 - 1.2e-75 254.3 0.0 1.9e-75 253.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain AdenylateSensor PF16579.5 KSA04131.1 - 7e-56 187.7 0.1 1.5e-55 186.7 0.1 1.6 1 0 0 1 1 1 1 Adenylate sensor of SNF1-like protein kinase Pkinase_Tyr PF07714.17 KSA04131.1 - 1.1e-38 133.1 0.0 2.1e-38 132.1 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase UBA_2 PF08587.11 KSA04131.1 - 1.8e-21 76.0 0.9 7.6e-21 74.0 0.2 2.3 2 0 0 2 2 2 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.6 KSA04131.1 - 2.1e-08 33.8 0.0 6.8e-08 32.2 0.0 1.7 1 1 0 2 2 2 1 Kinase-like RIO1 PF01163.22 KSA04131.1 - 9.3e-05 22.1 0.5 0.00018 21.2 0.5 1.4 1 0 0 1 1 1 1 RIO1 family YukC PF10140.9 KSA04131.1 - 0.00018 20.5 0.3 0.00035 19.5 0.3 1.4 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC Haspin_kinase PF12330.8 KSA04131.1 - 0.0016 17.5 0.3 0.0016 17.5 0.3 1.7 2 1 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 KSA04131.1 - 0.0049 16.2 0.0 0.011 15.2 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2443 PF10398.9 KSA04131.1 - 0.079 13.0 0.1 0.21 11.6 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2443) APH PF01636.23 KSA04131.1 - 0.13 12.2 0.1 0.26 11.2 0.1 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family PWI PF01480.17 KSA04132.1 - 1.2e-19 70.3 0.8 2e-19 69.7 0.8 1.4 1 0 0 1 1 1 1 PWI domain Unstab_antitox PF09720.10 KSA04132.1 - 0.063 13.3 0.1 0.14 12.2 0.1 1.5 1 0 0 1 1 1 0 Putative addiction module component Arena_ncap_C PF17290.2 KSA04132.1 - 0.067 12.5 0.6 0.11 11.8 0.6 1.4 1 0 0 1 1 1 0 Arenavirus nucleocapsid C-terminal domain NiFe-hyd_HybE PF11939.8 KSA04132.1 - 0.091 12.7 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 [NiFe]-hydrogenase assembly, chaperone, HybE YTH PF04146.15 KSA04133.1 - 1.2e-36 126.1 0.7 2.9e-36 124.9 0.2 1.9 2 0 0 2 2 2 1 YT521-B-like domain COQ7 PF03232.13 KSA04134.1 - 1.1e-75 253.2 0.0 1.4e-75 252.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.17 KSA04134.1 - 0.018 15.4 0.0 0.059 13.8 0.0 1.8 2 0 0 2 2 2 0 Rubrerythrin Nuf2 PF03800.14 KSA04135.1 - 7.6e-46 155.7 0.8 7.6e-46 155.7 0.8 2.6 2 0 0 2 2 2 1 Nuf2 family DHR10 PF18595.1 KSA04135.1 - 2.9e-25 88.6 20.6 2.9e-25 88.6 20.6 4.1 3 1 1 4 4 4 1 Designed helical repeat protein 10 domain ScsC_N PF18312.1 KSA04135.1 - 0.07 13.0 0.5 0.21 11.4 0.1 2.0 2 0 0 2 2 2 0 Copper resistance protein ScsC N-terminal domain CSN5_C PF18323.1 KSA04135.1 - 0.14 13.1 23.8 3.8 8.5 3.1 3.8 2 1 1 3 3 3 0 Cop9 signalosome subunit 5 C-terminal domain NTR PF01759.21 KSA04135.1 - 0.39 10.5 6.0 0.12 12.2 2.8 1.8 2 0 0 2 2 2 0 UNC-6/NTR/C345C module YoeB_toxin PF06769.14 KSA04135.1 - 0.46 10.5 2.9 28 4.8 0.1 3.1 2 1 1 3 3 3 0 YoeB-like toxin of bacterial type II toxin-antitoxin system T3SS_needle_E PF08988.10 KSA04135.1 - 0.77 9.9 6.7 2.4 8.4 0.2 3.3 2 1 1 3 3 3 0 Type III secretion system, cytoplasmic E component of needle TACC_C PF05010.14 KSA04135.1 - 1.6 8.5 47.3 4.6 7.0 26.8 2.7 1 1 2 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Cob_adeno_trans PF01923.18 KSA04135.1 - 2 8.5 17.4 1.2e+02 2.8 0.5 3.4 1 1 0 2 2 2 0 Cobalamin adenosyltransferase ApoO PF09769.9 KSA04135.1 - 2.3 8.2 7.0 1.3 9.0 1.6 2.7 2 0 0 2 2 2 0 Apolipoprotein O SlyX PF04102.12 KSA04135.1 - 3.6 8.3 22.5 1.9 9.1 6.6 4.9 3 2 2 6 6 5 0 SlyX FPP PF05911.11 KSA04135.1 - 7.5 4.6 51.4 4.5 5.3 19.6 2.1 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil DUF745 PF05335.13 KSA04135.1 - 9.4 5.9 26.8 1.1 8.9 10.3 3.1 2 1 0 3 3 3 0 Protein of unknown function (DUF745) MFS_1 PF07690.16 KSA04136.1 - 7.1e-36 123.9 42.4 3.4e-34 118.3 43.8 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KSA04136.1 - 2.7e-17 62.4 25.6 4.8e-16 58.3 25.7 2.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) EbsA PF17255.2 KSA04136.1 - 0.59 10.5 5.3 3.1 8.2 0.0 2.9 2 0 0 2 2 2 0 EbsA-like protein DUF4407 PF14362.6 KSA04136.1 - 1.6 8.0 4.3 1.1 8.6 0.3 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Git3 PF11710.8 KSA04137.1 - 1.5e-80 269.7 18.7 2.9e-80 268.8 18.7 1.4 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 KSA04137.1 - 4e-35 119.7 4.1 4e-35 119.7 4.1 2.1 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term Beta_protein PF14350.6 KSA04137.1 - 0.03 13.7 0.2 0.064 12.7 0.2 1.5 1 0 0 1 1 1 0 Beta protein AA_permease PF00324.21 KSA04138.1 - 3e-112 375.7 31.4 3.5e-112 375.4 31.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KSA04138.1 - 8.4e-26 90.8 36.2 1.2e-25 90.2 36.2 1.1 1 0 0 1 1 1 1 Amino acid permease TraL PF07178.11 KSA04138.1 - 4.4 7.8 12.4 9.2 6.8 0.1 3.9 4 0 0 4 4 4 0 TraL protein Sod_Cu PF00080.20 KSA04139.1 - 1.4e-15 57.7 0.3 2e-15 57.2 0.3 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Abhydrolase_1 PF00561.20 KSA04140.1 - 1.5e-21 77.2 0.1 3.2e-21 76.1 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 KSA04140.1 - 9.4e-21 73.2 0.0 1.9e-20 72.2 0.0 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 KSA04140.1 - 4.8e-05 22.7 0.0 0.00014 21.3 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 KSA04140.1 - 0.0017 18.2 0.0 1.1 9.0 0.0 2.7 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase zf-C2H2_2 PF12756.7 KSA04141.1 - 0.02 15.2 4.2 0.049 14.0 4.2 1.7 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.15 KSA04141.1 - 0.27 11.3 2.6 0.69 10.0 2.6 1.7 1 0 0 1 1 1 0 BED zinc finger zf-H2C2_2 PF13465.6 KSA04141.1 - 0.33 11.5 4.4 1 9.9 0.8 2.8 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2 PF00096.26 KSA04141.1 - 6.6 7.4 11.0 0.51 10.9 1.9 2.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2 PF00096.26 KSA04142.1 - 0.00013 22.2 8.1 0.052 14.0 0.1 3.5 3 1 0 3 3 3 2 Zinc finger, C2H2 type zf-Di19 PF05605.12 KSA04142.1 - 0.01 16.1 2.0 0.042 14.1 2.1 2.0 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf_ZIC PF18366.1 KSA04142.1 - 0.12 12.5 0.4 0.47 10.6 0.1 2.1 2 0 0 2 2 2 0 Zic proteins zinc finger domain zf-C2H2_4 PF13894.6 KSA04142.1 - 0.25 12.3 0.3 0.25 12.3 0.3 4.0 3 1 0 3 3 3 0 C2H2-type zinc finger CRC_subunit PF08624.10 KSA04143.1 - 3.1e-49 166.9 0.2 3.1e-49 166.9 0.2 2.0 2 0 0 2 2 2 1 Chromatin remodelling complex Rsc7/Swp82 subunit SDA1 PF05285.12 KSA04143.1 - 0.36 10.2 37.9 0.58 9.5 37.9 1.3 1 0 0 1 1 1 0 SDA1 LAP1C PF05609.12 KSA04143.1 - 5.9 5.9 19.5 8 5.4 19.5 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Peptidase_M41 PF01434.18 KSA04144.1 - 2.1e-66 223.4 0.0 4.2e-66 222.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 KSA04144.1 - 5.2e-43 146.6 0.3 4.6e-42 143.6 0.0 2.6 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KSA04144.1 - 1.8e-11 43.6 0.0 5.7e-11 42.0 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 KSA04144.1 - 1.6e-07 31.6 0.5 1.6e-07 31.6 0.5 2.1 2 0 0 2 2 2 1 FtsH Extracellular AAA_2 PF07724.14 KSA04144.1 - 0.004 17.3 0.5 0.017 15.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KSA04144.1 - 0.005 16.9 0.8 0.067 13.2 0.0 3.1 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 KSA04144.1 - 0.0055 16.0 0.0 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 KSA04144.1 - 0.0088 16.3 1.2 2 8.7 0.1 3.6 2 1 0 3 3 3 1 AAA domain RuvB_N PF05496.12 KSA04144.1 - 0.0092 15.7 0.0 0.038 13.7 0.0 2.2 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_17 PF13207.6 KSA04144.1 - 0.028 14.8 1.4 0.059 13.8 0.0 2.3 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 KSA04144.1 - 0.037 14.4 0.1 0.18 12.2 0.1 2.1 1 1 0 1 1 1 0 AAA ATPase domain IstB_IS21 PF01695.17 KSA04144.1 - 0.051 13.3 0.0 0.14 11.8 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_18 PF13238.6 KSA04144.1 - 0.12 13.0 0.4 1.2 9.7 0.0 3.0 3 1 0 3 3 3 0 AAA domain Exo_endo_phos PF03372.23 KSA04145.1 - 1.9e-06 27.6 0.1 2.6e-06 27.1 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Med26 PF08711.11 KSA04145.1 - 0.031 14.3 0.0 0.06 13.4 0.0 1.5 1 0 0 1 1 1 0 TFIIS helical bundle-like domain LCAT PF02450.15 KSA04146.1 - 7.3e-08 32.0 0.0 1.4e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_1 PF00561.20 KSA04146.1 - 5.5e-05 22.9 0.1 0.00011 21.9 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 KSA04146.1 - 0.0003 20.5 0.0 0.00064 19.4 0.0 1.5 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 KSA04146.1 - 0.00087 18.6 0.0 0.0016 17.7 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KSA04146.1 - 0.022 15.3 0.0 0.037 14.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.13 KSA04146.1 - 0.046 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein zf-CSL PF05207.13 KSA04147.1 - 1.2e-17 63.4 3.6 1.8e-17 62.8 3.6 1.3 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.31 KSA04147.1 - 2.8e-08 33.7 0.0 4.7e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain RNA_pol_I_A49 PF06870.12 KSA04148.1 - 2.2e-116 388.9 0.9 2.6e-116 388.7 0.9 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor DMAP1 PF05499.12 KSA04148.1 - 0.0036 17.2 0.1 0.0084 16.0 0.1 1.6 1 0 0 1 1 1 1 DNA methyltransferase 1-associated protein 1 (DMAP1) NAP PF00956.18 KSA04149.1 - 7.4e-13 48.3 5.3 7.4e-13 48.3 5.3 1.8 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) TFIIB PF00382.19 KSA04150.1 - 2.4e-42 142.8 0.2 7.6e-22 77.1 0.0 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 KSA04150.1 - 4e-13 48.6 1.1 7.1e-13 47.8 1.1 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding zf-ribbon_3 PF13248.6 KSA04150.1 - 0.0051 16.2 0.7 0.19 11.1 0.0 2.5 2 0 0 2 2 2 1 zinc-ribbon domain DUF2824 PF11039.8 KSA04150.1 - 0.078 12.9 0.0 0.31 11.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2824) HTH_34 PF13601.6 KSA04150.1 - 0.12 12.5 0.1 4.2 7.6 0.0 2.4 2 0 0 2 2 2 0 Winged helix DNA-binding domain FAD_binding_3 PF01494.19 KSA04151.1 - 4.8e-17 62.2 0.0 2.3e-13 50.1 0.0 3.0 2 1 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 KSA04151.1 - 3.2e-05 23.1 0.1 0.0015 17.7 0.1 2.4 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KSA04151.1 - 0.0026 17.0 0.0 0.006 15.8 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KSA04151.1 - 0.0045 15.9 0.1 0.21 10.4 0.0 2.4 3 0 0 3 3 3 1 Tryptophan halogenase SE PF08491.10 KSA04151.1 - 0.0076 15.3 0.0 0.01 14.9 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase NAD_binding_9 PF13454.6 KSA04151.1 - 0.027 14.5 0.0 0.05 13.6 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding UPF0052 PF01933.18 KSA04151.1 - 0.08 12.2 0.0 0.19 10.9 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised protein family UPF0052 Thi4 PF01946.17 KSA04151.1 - 0.092 12.0 0.1 0.55 9.4 0.1 2.2 2 1 1 3 3 3 0 Thi4 family DAO PF01266.24 KSA04151.1 - 0.13 11.8 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase DUF3417 PF11897.8 KSA04151.1 - 0.14 12.7 0.1 0.28 11.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3417) NAD_binding_8 PF13450.6 KSA04151.1 - 0.17 12.2 0.1 0.38 11.0 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KSA04151.1 - 0.19 10.4 0.0 0.3 9.7 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein PGAP1 PF07819.13 KSA04152.1 - 5.5e-08 32.8 0.3 9.4e-08 32.0 0.3 1.6 1 1 0 1 1 1 1 PGAP1-like protein Palm_thioest PF02089.15 KSA04152.1 - 2.3e-06 27.7 0.2 6e-06 26.3 0.2 1.8 1 1 0 1 1 1 1 Palmitoyl protein thioesterase DUF676 PF05057.14 KSA04152.1 - 1e-05 25.2 0.1 2.2e-05 24.1 0.1 1.6 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.20 KSA04152.1 - 6.3e-05 22.7 0.0 0.00016 21.4 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF915 PF06028.11 KSA04152.1 - 0.00012 21.6 0.2 0.043 13.2 0.0 3.2 3 0 0 3 3 3 1 Alpha/beta hydrolase of unknown function (DUF915) LCAT PF02450.15 KSA04152.1 - 0.0005 19.4 0.0 0.00067 18.9 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Hydrolase_4 PF12146.8 KSA04152.1 - 0.071 12.4 0.0 0.15 11.3 0.0 1.7 1 1 0 1 1 1 0 Serine aminopeptidase, S33 DUF900 PF05990.12 KSA04152.1 - 0.078 12.5 0.1 0.17 11.3 0.0 1.5 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) Mst1_SARAH PF11629.8 KSA04152.1 - 0.18 11.9 0.9 2 8.6 0.1 2.8 3 0 0 3 3 3 0 C terminal SARAH domain of Mst1 Aldedh PF00171.22 KSA04153.1 - 4.6e-118 394.7 0.0 5.5e-118 394.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KSA04153.1 - 0.0023 17.0 0.0 0.0045 16.1 0.0 1.4 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) BAR_3 PF16746.5 KSA04154.1 - 2.2e-20 73.4 0.8 5.5e-20 72.1 0.3 1.9 2 0 0 2 2 2 1 BAR domain of APPL family PH PF00169.29 KSA04154.1 - 4.5e-09 36.8 0.4 2.8e-08 34.2 0.4 2.5 1 0 0 1 1 1 1 PH domain VASt PF16016.5 KSA04154.1 - 0.0097 16.3 0.1 0.03 14.7 0.1 1.9 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 KSA04154.1 - 0.027 14.3 0.1 0.11 12.4 0.1 2.1 1 0 0 1 1 1 0 GRAM domain Jiv90 PF14901.6 KSA04154.1 - 0.077 13.2 1.5 0.39 10.9 1.5 2.2 1 0 0 1 1 1 0 Cleavage inducing molecular chaperone Hrs_helical PF12210.8 KSA04154.1 - 0.17 12.4 1.0 5.3 7.6 0.1 2.8 2 0 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate BLOC1_2 PF10046.9 KSA04154.1 - 2.7 8.3 5.7 7.2 7.0 0.0 3.6 4 0 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 AA_permease_C PF13906.6 KSA04154.1 - 5.9 7.1 6.6 0.27 11.4 0.7 1.8 2 0 0 2 2 2 0 C-terminus of AA_permease AA_permease PF00324.21 KSA04155.1 - 5.6e-137 457.2 44.2 7e-137 456.9 44.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KSA04155.1 - 1.1e-38 133.2 47.1 1.4e-38 132.9 47.1 1.0 1 0 0 1 1 1 1 Amino acid permease Ribonuc_L-PSP PF01042.21 KSA04156.1 - 1.1e-21 77.1 0.0 1.3e-21 76.9 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Abi_2 PF07751.11 KSA04156.1 - 0.011 16.0 0.1 0.013 15.7 0.1 1.3 1 1 0 1 1 1 0 Abi-like protein ETC_C1_NDUFA4 PF04800.12 KSA04156.1 - 0.088 13.1 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 ETC complex I subunit conserved region DCB PF16213.5 KSA04157.1 - 8.6e-42 142.8 5.3 4.4e-41 140.5 5.3 2.4 1 0 0 1 1 1 1 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 KSA04157.1 - 1.2e-41 142.2 1.1 1.2e-41 142.2 1.1 4.5 3 1 1 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Mon2_C PF16206.5 KSA04157.1 - 9.1e-14 50.6 1.4 5.1e-12 44.8 0.1 3.1 3 0 0 3 3 3 1 C-terminal region of Mon2 protein DUF1981 PF09324.10 KSA04157.1 - 0.0015 18.4 13.2 2.6 8.0 0.0 6.8 5 1 0 6 6 6 2 Domain of unknown function (DUF1981) BSD PF03909.17 KSA04157.1 - 0.38 10.8 1.9 48 4.1 0.0 3.9 3 0 0 3 3 3 0 BSD domain Chitin_synth_2 PF03142.15 KSA04158.1 - 2.5e-279 927.3 1.1 2.5e-279 927.3 1.1 1.4 2 0 0 2 2 2 1 Chitin synthase Glyco_trans_2_3 PF13632.6 KSA04158.1 - 2.7e-12 47.0 2.0 9.8e-12 45.2 2.0 2.0 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KSA04158.1 - 1.1e-10 41.8 0.0 3.6e-10 40.1 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KSA04158.1 - 0.00042 19.8 0.3 0.0017 17.9 0.1 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 KSA04158.1 - 0.009 15.8 0.0 0.038 13.8 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 2 Cyt-b5 PF00173.28 KSA04158.1 - 0.06 13.5 0.1 0.23 11.6 0.0 2.0 2 0 0 2 2 2 0 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.24 KSA04160.1 - 1.1e-23 84.4 18.5 1.5e-23 84.0 18.5 1.1 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 KSA04160.1 - 4.2e-05 23.8 0.0 7.5e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Holin_SPP1 PF04688.13 KSA04160.1 - 0.18 12.0 1.3 0.28 11.4 0.4 1.8 2 0 0 2 2 2 0 SPP1 phage holin GTP_EFTU PF00009.27 KSA04161.1 - 3.7e-62 209.3 0.1 6.5e-62 208.5 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 KSA04161.1 - 9.2e-36 122.3 0.0 2.2e-35 121.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 KSA04161.1 - 4.7e-30 103.5 0.0 1.1e-29 102.4 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 KSA04161.1 - 1.9e-22 79.1 0.0 5.2e-22 77.7 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KSA04161.1 - 1.5e-12 47.7 0.1 4e-12 46.4 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 KSA04161.1 - 1e-06 28.6 0.0 2.1e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain AvrPtoB_bdg PF16847.5 KSA04161.1 - 0.0062 17.0 0.0 0.11 12.9 0.0 2.6 2 0 0 2 2 2 1 Avirulence AvrPtoB, BAK1-binding domain MMR_HSR1 PF01926.23 KSA04161.1 - 0.015 15.4 0.0 0.041 14.0 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase Ribosomal_L14e PF01929.17 KSA04162.1 - 3.6e-33 113.9 1.3 6.3e-33 113.1 1.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L14 tRNA-synt_1e PF01406.19 KSA04163.1 - 6.1e-137 456.0 0.2 6.1e-137 456.0 0.2 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 KSA04163.1 - 1.5e-09 37.1 6.6 4.8e-05 22.3 0.1 2.6 3 0 0 3 3 3 2 tRNA synthetases class I (M) tRNA-synt_1f PF01921.18 KSA04163.1 - 0.00019 20.5 0.1 0.054 12.4 0.1 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (K) tRNA-synt_1 PF00133.22 KSA04163.1 - 0.00037 18.9 0.0 0.00037 18.9 0.0 2.4 3 0 0 3 3 3 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1c PF00749.21 KSA04163.1 - 0.033 13.1 2.0 0.13 11.1 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain RXLR PF16810.5 KSA04163.1 - 0.052 14.0 6.2 0.11 13.0 6.2 1.5 1 0 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity SPC22 PF04573.12 KSA04164.1 - 6.6e-54 182.0 0.3 7.6e-54 181.7 0.3 1.0 1 0 0 1 1 1 1 Signal peptidase subunit PPR_2 PF13041.6 KSA04165.1 - 1.7e-10 40.9 5.8 0.0012 19.0 0.0 6.8 7 0 0 7 7 7 2 PPR repeat family TPR_19 PF14559.6 KSA04165.1 - 3.8e-05 24.1 2.5 1 9.9 0.1 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat PPR PF01535.20 KSA04165.1 - 0.0026 17.9 12.3 5.2 7.5 0.0 7.0 9 0 0 9 9 8 2 PPR repeat PPR_3 PF13812.6 KSA04165.1 - 0.017 15.2 9.7 0.83 9.8 0.1 6.2 6 1 1 7 7 7 0 Pentatricopeptide repeat domain TPR_14 PF13428.6 KSA04165.1 - 0.02 15.6 0.6 34 5.6 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat MNE1 PF13762.6 KSA04165.1 - 0.086 12.8 15.7 0.46 10.4 0.1 5.8 5 1 1 6 6 6 0 Mitochondrial splicing apparatus component SPO22 PF08631.10 KSA04165.1 - 0.1 12.1 5.0 0.13 11.7 0.1 3.0 3 1 0 3 3 3 0 Meiosis protein SPO22/ZIP4 like ERAP1_C PF11838.8 KSA04165.1 - 0.13 11.8 1.4 1.7 8.1 0.1 2.9 3 0 0 3 3 3 0 ERAP1-like C-terminal domain TPR_12 PF13424.6 KSA04165.1 - 0.27 11.6 1.9 20 5.5 0.0 4.1 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 KSA04165.1 - 0.71 10.1 8.2 0.25 11.5 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 KSA04165.1 - 5.7 7.4 6.1 40 4.8 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 KSA04165.1 - 7.4 6.6 11.4 0.88 9.5 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Yip1 PF04893.17 KSA04166.1 - 2.2e-10 40.5 3.5 2.2e-10 40.5 3.5 1.8 1 1 1 2 2 2 1 Yip1 domain MMS1_N PF10433.9 KSA04167.1 - 1.2e-54 185.7 6.1 1.2e-54 185.7 6.1 1.9 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term FH2 PF02181.23 KSA04168.1 - 1.6e-91 307.3 13.4 1.6e-91 307.3 13.4 2.6 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 KSA04168.1 - 6.5e-47 159.7 1.1 6.5e-47 159.7 1.1 4.1 4 0 0 4 4 4 2 Diaphanous FH3 Domain Drf_GBD PF06371.13 KSA04168.1 - 3.3e-37 127.9 0.2 3.3e-37 127.9 0.2 2.3 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Sec2p PF06428.11 KSA04169.1 - 1.7e-24 85.6 12.1 1.7e-24 85.6 12.1 3.6 2 1 1 3 3 3 1 GDP/GTP exchange factor Sec2p Scaffolding_pro PF11418.8 KSA04169.1 - 0.0039 17.7 0.8 0.0039 17.7 0.8 2.5 2 0 0 2 2 2 1 Phi29 scaffolding protein BRE1 PF08647.11 KSA04169.1 - 2.7 8.1 33.9 0.65 10.1 10.4 3.8 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase Nup54 PF13874.6 KSA04169.1 - 2.9 8.0 9.8 17 5.5 9.8 2.4 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 DUF5340 PF17275.2 KSA04170.1 - 0.029 14.5 0.1 0.1 12.7 0.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5340) F-box-like PF12937.7 KSA04170.1 - 0.031 14.2 0.1 0.062 13.2 0.1 1.6 1 0 0 1 1 1 0 F-box-like Sugar_tr PF00083.24 KSA04171.1 - 1.2e-43 149.7 17.5 1.8e-43 149.1 17.5 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KSA04171.1 - 6.1e-25 87.9 17.9 3.5e-20 72.3 12.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PAP2 PF01569.21 KSA04172.1 - 4e-29 101.1 2.0 4e-29 101.1 2.0 1.9 2 0 0 2 2 2 1 PAP2 superfamily Ost4 PF10215.9 KSA04172.1 - 0.013 15.3 0.5 0.013 15.3 0.5 3.0 4 0 0 4 4 4 0 Oligosaccaryltransferase 2TM PF13239.6 KSA04172.1 - 0.1 12.9 0.7 0.1 12.9 0.7 2.3 3 0 0 3 3 3 0 2TM domain DUF2304 PF10066.9 KSA04172.1 - 1.1 9.5 12.2 2 8.7 0.2 3.2 3 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2304) DUF3285 PF11688.8 KSA04172.1 - 3.2 7.7 4.8 1.7 8.6 0.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3285) S-AdoMet_synt_C PF02773.16 KSA04173.1 - 1.9e-66 222.3 0.1 4e-66 221.2 0.1 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 KSA04173.1 - 5.9e-46 155.6 0.0 1.2e-45 154.6 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 KSA04173.1 - 8.8e-45 151.4 0.3 8.8e-45 151.4 0.3 1.7 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.19 KSA04173.1 - 0.009 14.8 0.5 0.13 11.0 0.1 2.2 1 1 0 2 2 2 1 S-adenosylmethionine synthetase (AdoMet synthetase) MRC1 PF09444.10 KSA04174.1 - 3.4e-37 128.2 18.1 3.4e-37 128.2 18.1 7.3 4 3 2 6 6 6 1 MRC1-like domain KH_8 PF17903.1 KSA04176.1 - 2.8e-32 110.6 0.1 7.2e-32 109.3 0.1 1.7 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 KSA04176.1 - 0.035 13.9 0.0 0.1 12.4 0.0 1.8 2 0 0 2 2 2 0 KH domain KELK PF15796.5 KSA04177.1 - 0.0073 16.7 0.8 0.0073 16.7 0.8 2.0 2 0 0 2 2 2 1 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4337 PF14235.6 KSA04177.1 - 1.8 8.6 5.9 2 8.5 5.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Pkinase PF00069.25 KSA04178.1 - 3.1e-71 239.8 0.0 7.3e-71 238.6 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KSA04178.1 - 1e-34 120.0 0.0 1.9e-34 119.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Fungal_KA1 PF16797.5 KSA04178.1 - 5.6e-34 116.4 3.4 1.8e-33 114.7 3.4 2.0 1 0 0 1 1 1 1 Fungal kinase associated-1 domain Kinase-like PF14531.6 KSA04178.1 - 5.8e-05 22.6 0.4 0.0035 16.7 0.0 2.8 3 0 0 3 3 3 1 Kinase-like APH PF01636.23 KSA04178.1 - 0.026 14.4 0.0 0.069 13.1 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF501 PF04417.12 KSA04178.1 - 0.17 11.7 2.8 0.53 10.1 2.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF501) EMG1 PF03587.14 KSA04180.1 - 9.1e-79 263.6 0.0 1.1e-78 263.4 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase LCD1 PF09798.9 KSA04181.1 - 1.7e-187 624.7 34.8 1.9e-187 624.5 34.8 1.0 1 0 0 1 1 1 1 DNA damage checkpoint protein TMF_TATA_bd PF12325.8 KSA04181.1 - 0.0036 17.5 4.2 0.017 15.3 4.2 2.2 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding Asp-B-Hydro_N PF05279.11 KSA04181.1 - 0.9 9.6 7.8 1.9 8.5 7.8 1.5 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Ribosomal_L37e PF01907.19 KSA04182.1 - 4.7e-27 93.9 11.0 4.7e-27 93.9 11.0 1.4 2 0 0 2 2 2 1 Ribosomal protein L37e DZR PF12773.7 KSA04182.1 - 0.0029 17.6 1.7 0.0041 17.1 1.7 1.2 1 0 0 1 1 1 1 Double zinc ribbon SelR PF01641.18 KSA04182.1 - 0.011 15.8 1.0 0.013 15.5 1.0 1.3 1 1 0 1 1 1 0 SelR domain zf-ribbon_3 PF13248.6 KSA04182.1 - 0.041 13.3 3.1 0.077 12.4 3.1 1.5 1 1 0 1 1 1 0 zinc-ribbon domain zf-RING_5 PF14634.6 KSA04182.1 - 0.064 13.2 3.6 0.098 12.6 3.6 1.3 1 0 0 1 1 1 0 zinc-RING finger domain HypA PF01155.19 KSA04182.1 - 0.072 13.1 0.9 0.099 12.7 0.9 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF1258 PF06869.12 KSA04182.1 - 0.1 12.0 3.9 0.095 12.2 3.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1258) Zn-ribbon_8 PF09723.10 KSA04182.1 - 0.26 11.4 2.4 0.55 10.4 2.4 1.6 1 1 0 1 1 1 0 Zinc ribbon domain zf_C2H2_13 PF18508.1 KSA04182.1 - 0.3 10.7 2.2 5.5 6.7 0.3 2.2 2 0 0 2 2 2 0 Zinc finger domain zinc_ribbon_2 PF13240.6 KSA04182.1 - 0.54 10.0 5.4 6.6 6.6 0.7 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-HYPF PF07503.12 KSA04182.1 - 4.3 7.2 6.9 29 4.5 3.5 2.8 2 1 1 3 3 3 0 HypF finger FHA PF00498.26 KSA04183.1 - 7.9e-06 26.1 0.0 2.5e-05 24.6 0.0 1.9 1 0 0 1 1 1 1 FHA domain FHA_2 PF17913.1 KSA04183.1 - 0.06 13.6 0.0 0.19 12.0 0.0 1.8 1 0 0 1 1 1 0 FHA domain Yop-YscD_cpl PF16697.5 KSA04183.1 - 0.093 13.1 0.0 0.24 11.7 0.0 1.8 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain DUF948 PF06103.11 KSA04184.1 - 0.00096 19.4 11.9 0.0076 16.5 2.4 4.2 4 0 0 4 4 4 2 Bacterial protein of unknown function (DUF948) Spore_YhaL PF14147.6 KSA04184.1 - 0.12 12.1 0.7 7.1 6.4 0.1 3.0 2 0 0 2 2 2 0 Sporulation protein YhaL DUF3328 PF11807.8 KSA04184.1 - 0.14 11.9 0.9 3.9 7.2 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3328) Baculo_PEP_C PF04513.12 KSA04184.1 - 0.33 11.0 26.9 0.3 11.1 5.3 4.9 4 1 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus PDR_CDR PF06422.12 KSA04184.1 - 0.34 10.9 3.1 0.35 10.8 0.4 2.4 2 0 0 2 2 2 0 CDR ABC transporter Rad60-SLD PF11976.8 KSA04185.1 - 8.3e-17 60.8 0.0 1e-16 60.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KSA04185.1 - 2.4e-08 33.6 0.0 2.8e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family PSP1 PF04468.12 KSA04186.1 - 2.3e-29 101.5 2.1 5.1e-29 100.4 2.1 1.6 1 0 0 1 1 1 1 PSP1 C-terminal conserved region PAP2 PF01569.21 KSA04187.1 - 1.2e-24 86.6 1.8 2.3e-24 85.7 1.8 1.5 1 0 0 1 1 1 1 PAP2 superfamily UPF0014 PF03649.13 KSA04187.1 - 0.084 12.2 0.4 2.7 7.3 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0014) SH3_1 PF00018.28 KSA04188.1 - 3.3e-07 29.8 0.0 7.7e-07 28.6 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KSA04188.1 - 6.4e-06 25.9 0.0 1.3e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KSA04188.1 - 8.2e-05 22.2 0.0 0.00016 21.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SKG6 PF08693.10 KSA04188.1 - 0.0036 16.7 0.1 0.0072 15.7 0.1 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Mid2 PF04478.12 KSA04188.1 - 0.0095 15.8 1.1 0.018 14.9 0.0 2.0 2 0 0 2 2 2 1 Mid2 like cell wall stress sensor DUF4448 PF14610.6 KSA04188.1 - 0.033 14.0 0.0 0.1 12.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) DNA_photolyase PF00875.18 KSA04188.1 - 0.15 12.0 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 DNA photolyase PH PF00169.29 KSA04189.1 - 4.3e-09 36.8 0.1 1.7e-06 28.4 0.0 2.5 2 0 0 2 2 2 2 PH domain Vta1 PF04652.16 KSA04190.1 - 1.8e-34 118.8 0.9 1.8e-34 118.8 0.9 1.6 2 0 0 2 2 2 1 Vta1 like Vta1_C PF18097.1 KSA04190.1 - 2.8e-15 55.7 0.7 5.2e-15 54.9 0.7 1.5 1 0 0 1 1 1 1 Vta1 C-terminal domain Sdh5 PF03937.16 KSA04191.1 - 6.9e-28 96.4 0.9 9.3e-28 96.0 0.9 1.2 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase Pneumo_M2 PF07380.11 KSA04191.1 - 0.024 14.9 0.0 0.07 13.4 0.0 1.8 2 0 0 2 2 2 0 Pneumovirus M2 protein EF-hand_7 PF13499.6 KSA04192.1 - 1.3e-13 51.2 9.1 5.6e-08 33.1 0.8 3.2 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KSA04192.1 - 2e-10 39.8 10.2 1.9e-05 24.2 0.1 5.3 6 0 0 6 6 6 2 EF-hand domain EF-hand_1 PF00036.32 KSA04192.1 - 1.4e-07 30.6 8.7 1.6e-05 24.1 0.1 5.1 5 1 0 5 5 5 2 EF hand EF-hand_8 PF13833.6 KSA04192.1 - 8.5e-05 22.3 4.6 0.0025 17.6 0.1 3.7 4 1 0 4 4 4 1 EF-hand domain pair S_100 PF01023.19 KSA04192.1 - 0.00098 18.8 6.0 0.0038 16.9 1.4 3.0 3 0 0 3 3 3 1 S-100/ICaBP type calcium binding domain EF-hand_4 PF12763.7 KSA04192.1 - 0.019 14.9 0.6 0.13 12.3 0.1 2.4 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand Ank_2 PF12796.7 KSA04193.1 - 9.4e-09 35.7 0.2 0.0049 17.4 0.2 3.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) KilA-N PF04383.13 KSA04193.1 - 1.4e-06 28.2 0.5 7.7e-06 25.7 0.0 2.5 2 0 0 2 2 2 1 KilA-N domain Ank PF00023.30 KSA04193.1 - 5.4e-06 26.6 2.0 0.2 12.2 0.0 4.0 5 0 0 5 5 5 2 Ankyrin repeat Ank_3 PF13606.6 KSA04193.1 - 1.4e-05 25.1 0.5 0.022 15.2 0.1 3.5 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 KSA04193.1 - 4.3e-05 23.7 0.0 0.009 16.3 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 KSA04193.1 - 0.0019 18.7 0.2 0.76 10.4 0.0 3.7 3 2 2 5 5 5 1 Ankyrin repeats (many copies) YhdB PF14148.6 KSA04193.1 - 0.044 13.9 0.1 0.59 10.3 0.0 2.9 2 0 0 2 2 2 0 YhdB-like protein Exonuc_VII_L PF02601.15 KSA04193.1 - 0.21 11.1 4.3 0.34 10.4 1.2 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit SEA PF01390.20 KSA04193.1 - 1.2 9.3 10.3 2 8.6 0.1 4.2 3 1 0 3 3 3 0 SEA domain SF3A2 PF16835.5 KSA04194.1 - 9.4e-32 109.3 0.2 1.7e-31 108.4 0.2 1.4 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 KSA04194.1 - 8.7e-06 25.9 0.6 2.1e-05 24.7 0.4 1.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type PAPS_reduct PF01507.19 KSA04195.1 - 4.6e-18 65.9 0.0 2.3e-16 60.3 0.0 2.0 1 1 1 2 2 2 2 Phosphoadenosine phosphosulfate reductase family Imm10 PF15588.6 KSA04195.1 - 0.13 12.4 0.1 0.24 11.5 0.1 1.3 1 0 0 1 1 1 0 Immunity protein 10 HLH PF00010.26 KSA04196.1 - 5.5e-16 58.3 0.6 1.1e-15 57.4 0.1 1.7 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain RRP14 PF15459.6 KSA04196.1 - 0.031 14.9 1.4 0.085 13.5 0.8 2.1 1 1 0 1 1 1 0 60S ribosome biogenesis protein Rrp14 DUF1910 PF08928.10 KSA04197.1 - 0.0062 16.5 0.1 0.0062 16.5 0.1 3.3 3 1 1 4 4 4 1 Domain of unknown function (DUF1910) Tubulin_2 PF13809.6 KSA04197.1 - 0.09 11.9 1.5 0.24 10.6 1.5 1.6 1 0 0 1 1 1 0 Tubulin like DUF2570 PF10828.8 KSA04197.1 - 0.24 11.2 2.4 0.31 10.9 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) Spore_II_R PF09551.10 KSA04197.1 - 3.7 8.0 7.6 1.1 9.7 1.6 2.6 2 1 0 2 2 2 0 Stage II sporulation protein R (spore_II_R) SIR2 PF02146.17 KSA04198.1 - 9.4e-63 211.3 0.0 1.6e-62 210.6 0.0 1.4 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.13 KSA04198.1 - 7.9e-34 116.6 4.3 4e-18 65.6 0.1 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.22 KSA04198.1 - 0.00048 19.9 0.0 0.74 9.5 0.0 2.4 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain Glutaredoxin PF00462.24 KSA04198.1 - 0.047 13.9 1.0 0.47 10.7 0.1 2.7 2 0 0 2 2 2 0 Glutaredoxin DUF4588 PF15251.6 KSA04198.1 - 0.44 10.3 9.0 0.7 9.6 9.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) CMAS PF02353.20 KSA04199.1 - 3.9e-63 213.3 1.1 4.8e-63 213.0 1.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 KSA04199.1 - 8.1e-13 48.5 0.0 1.4e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KSA04199.1 - 1.4e-08 35.3 0.0 2.8e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KSA04199.1 - 4.2e-08 33.7 0.0 8e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KSA04199.1 - 3.7e-05 24.4 0.0 7.2e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KSA04199.1 - 8e-05 22.8 0.0 0.00014 22.0 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 KSA04199.1 - 0.00017 21.4 0.0 0.00027 20.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 KSA04199.1 - 0.0063 16.1 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 MTS PF05175.14 KSA04199.1 - 0.037 13.6 0.0 0.059 12.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Malate_synthase PF01274.22 KSA04200.1 - 3.2e-227 755.0 0.0 3.6e-227 754.8 0.0 1.0 1 0 0 1 1 1 1 Malate synthase HpcH_HpaI PF03328.14 KSA04200.1 - 0.1 11.7 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 HpcH/HpaI aldolase/citrate lyase family Glutaredoxin PF00462.24 KSA04201.1 - 1.2e-11 44.7 0.0 2.4e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin UPF0160 PF03690.13 KSA04201.1 - 0.032 13.9 0.0 0.035 13.7 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0160) Thioredoxin_2 PF13098.6 KSA04201.1 - 0.058 13.9 0.0 0.17 12.3 0.0 1.8 1 0 0 1 1 1 0 Thioredoxin-like domain Ribosomal_S17_N PF16205.5 KSA04202.1 - 3.2e-31 107.5 0.8 6.5e-31 106.5 0.8 1.5 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 KSA04202.1 - 3.9e-27 94.1 2.0 3.9e-27 94.1 2.0 1.8 2 0 0 2 2 2 1 Ribosomal protein S17 ANAPC9 PF12856.7 KSA04203.1 - 3.7e-39 133.6 4.3 3.7e-39 133.6 4.3 3.3 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 9 NAD2 PF18782.1 KSA04203.1 - 0.019 15.1 0.1 0.033 14.3 0.1 1.3 1 0 0 1 1 1 0 Novel AID APOBEC clade 2 Pyr_redox_2 PF07992.14 KSA04204.1 - 3.5e-54 184.0 1.3 5.5e-54 183.4 1.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KSA04204.1 - 2.9e-34 117.6 0.3 1.6e-33 115.2 0.1 2.2 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KSA04204.1 - 3.7e-18 65.9 4.3 6.5e-16 58.7 0.4 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KSA04204.1 - 3.3e-09 36.4 1.1 1.4e-06 27.8 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KSA04204.1 - 2.2e-08 33.2 0.8 0.0063 15.3 0.0 3.0 3 0 0 3 3 3 2 HI0933-like protein FAD_oxidored PF12831.7 KSA04204.1 - 9.6e-07 28.5 0.0 1.4e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 KSA04204.1 - 2.4e-06 26.9 5.3 2.6e-05 23.5 0.0 3.2 2 1 1 3 3 3 1 Glucose inhibited division protein A 2-Hacid_dh_C PF02826.19 KSA04204.1 - 0.00045 19.6 1.0 0.85 9.0 0.0 3.3 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KSA04204.1 - 0.00073 18.9 0.6 0.057 12.7 0.1 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 KSA04204.1 - 0.00092 18.4 0.7 0.0025 17.0 0.7 1.7 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KSA04204.1 - 0.01 16.0 2.0 0.01 16.0 2.0 2.1 2 0 0 2 2 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KSA04204.1 - 0.012 14.8 0.1 0.035 13.4 0.1 1.8 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.19 KSA04204.1 - 0.03 13.6 0.7 1.6 7.9 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain NAD_binding_7 PF13241.6 KSA04204.1 - 0.035 14.5 0.1 0.86 10.1 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding 3HCDH_N PF02737.18 KSA04204.1 - 0.05 13.5 5.5 0.15 11.9 0.1 2.6 3 0 0 3 3 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF3888 PF13027.6 KSA04204.1 - 0.083 13.3 0.1 0.26 11.8 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3888) DAO PF01266.24 KSA04204.1 - 0.093 12.3 0.1 0.093 12.3 0.1 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase K_oxygenase PF13434.6 KSA04204.1 - 0.19 10.9 0.0 0.31 10.1 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) LSM PF01423.22 KSA04205.1 - 5.4e-12 45.2 0.8 6.5e-12 45.0 0.8 1.1 1 0 0 1 1 1 1 LSM domain Zn_clus PF00172.18 KSA04206.1 - 7.2e-08 32.4 6.6 2.1e-07 31.0 6.6 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pox_A_type_inc PF04508.12 KSA04206.1 - 4 7.4 5.3 2.2 8.3 1.5 2.4 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat ABC1 PF03109.16 KSA04207.1 - 4.9e-34 117.0 0.0 8.9e-34 116.2 0.0 1.4 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.22 KSA04207.1 - 0.0016 18.1 0.1 0.015 14.9 0.0 2.2 2 0 0 2 2 2 1 RIO1 family rRNA_processing PF08524.11 KSA04208.1 - 1e-43 148.9 26.2 1.2e-43 148.7 26.2 1.0 1 0 0 1 1 1 1 rRNA processing CLN3 PF02487.17 KSA04208.1 - 1.7 7.6 3.1 2.2 7.3 3.1 1.2 1 0 0 1 1 1 0 CLN3 protein CDC45 PF02724.14 KSA04208.1 - 2 6.6 14.1 2.4 6.4 14.1 1.0 1 0 0 1 1 1 0 CDC45-like protein Atg14 PF10186.9 KSA04208.1 - 3.6 6.6 15.1 4.1 6.4 15.1 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 zf-HIT PF04438.16 KSA04209.1 - 3.6e-09 36.3 12.2 5.8e-09 35.7 12.2 1.4 1 0 0 1 1 1 1 HIT zinc finger LTXXQ PF07813.12 KSA04209.1 - 0.038 14.7 2.6 0.057 14.1 1.5 2.1 1 1 1 2 2 2 0 LTXXQ motif family protein zf-MYND PF01753.18 KSA04209.1 - 0.045 13.8 11.0 0.13 12.3 11.0 1.9 1 1 0 1 1 1 0 MYND finger zf-B_box PF00643.24 KSA04209.1 - 0.31 11.2 10.9 0.54 10.5 10.9 1.5 1 0 0 1 1 1 0 B-box zinc finger Podoplanin PF05808.11 KSA04209.1 - 0.33 11.1 1.1 0.49 10.5 1.1 1.3 1 0 0 1 1 1 0 Podoplanin YebO PF13974.6 KSA04209.1 - 1.9 8.6 4.2 20 5.3 0.6 3.0 3 0 0 3 3 3 0 YebO-like protein Aa_trans PF01490.18 KSA04210.1 - 3e-76 256.8 32.5 3.7e-76 256.5 32.5 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF4985 PF16373.5 KSA04210.1 - 0.036 14.5 0.1 2.1 8.8 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function TIMELESS PF04821.14 KSA04211.1 - 1.3e-83 280.5 6.5 1.3e-83 280.5 6.5 2.7 3 0 0 3 3 3 1 Timeless protein DUF4806 PF16064.5 KSA04211.1 - 0.13 12.5 6.8 1.1 9.5 0.1 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4806) Fungal_trans PF04082.18 KSA04212.1 - 3.1e-07 29.7 0.5 3.1e-07 29.7 0.5 2.3 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KSA04212.1 - 1e-05 25.5 11.8 3.1e-05 24.0 11.8 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PPP4R2 PF09184.11 KSA04212.1 - 0.0024 17.5 11.7 0.0024 17.5 11.7 2.6 2 0 0 2 2 2 1 PPP4R2 DDHD PF02862.17 KSA04212.1 - 0.12 12.5 19.1 0.11 12.6 7.1 2.4 2 0 0 2 2 2 0 DDHD domain TFIIA PF03153.13 KSA04212.1 - 0.38 10.7 66.5 1.3 9.0 66.6 1.7 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Fungal_trans PF04082.18 KSA04213.1 - 3.4e-10 39.4 3.3 5.5e-10 38.7 0.1 2.5 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KSA04213.1 - 1.5e-08 34.6 7.4 2.9e-08 33.7 7.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cyclin_N PF00134.23 KSA04214.1 - 7.4e-20 71.0 0.1 7.4e-20 71.0 0.1 2.3 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin PF08613.11 KSA04214.1 - 1.2e-09 38.8 0.0 1.2e-09 38.8 0.0 2.5 2 1 0 2 2 1 1 Cyclin DUF1635 PF07795.11 KSA04214.1 - 0.00036 20.5 14.3 0.00039 20.4 11.5 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1635) Androgen_recep PF02166.16 KSA04214.1 - 0.035 13.0 8.9 0.046 12.6 8.9 1.1 1 0 0 1 1 1 0 Androgen receptor TFIIA PF03153.13 KSA04214.1 - 0.076 13.0 14.2 0.1 12.6 14.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TERB2 PF15101.6 KSA04214.1 - 0.083 12.9 5.9 0.12 12.4 5.9 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 NuiA PF07924.11 KSA04214.1 - 0.16 12.4 3.4 0.34 11.3 3.4 1.5 1 0 0 1 1 1 0 Nuclease A inhibitor-like protein CDT1_C PF16679.5 KSA04214.1 - 0.22 12.0 8.3 0.19 12.2 6.4 1.9 2 0 0 2 2 1 0 DNA replication factor Cdt1 C-terminal domain MPM1 PF17234.2 KSA04214.1 - 0.36 11.1 6.8 0.59 10.4 6.8 1.3 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 Spt20 PF12090.8 KSA04214.1 - 0.39 10.3 19.9 0.39 10.3 15.8 2.1 2 0 0 2 2 2 0 Spt20 family Roughex PF06020.11 KSA04214.1 - 0.41 9.7 6.0 0.63 9.1 6.0 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Tctex-1 PF03645.13 KSA04214.1 - 0.49 10.7 0.0 0.49 10.7 0.0 2.3 2 1 0 2 2 1 0 Tctex-1 family Kinesin_assoc PF16183.5 KSA04214.1 - 0.72 10.0 3.1 1.6 8.8 3.1 1.6 1 0 0 1 1 1 0 Kinesin-associated DUF4692 PF15763.5 KSA04214.1 - 0.99 9.9 10.1 1.2 9.6 6.7 2.1 2 0 0 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) FAM76 PF16046.5 KSA04214.1 - 2 7.7 13.2 3.1 7.1 13.2 1.2 1 0 0 1 1 1 0 FAM76 protein Ctr PF04145.15 KSA04214.1 - 4 8.0 5.7 4.7 7.8 5.1 1.5 1 1 0 1 1 1 0 Ctr copper transporter family DUF4634 PF15465.6 KSA04215.1 - 1.9 8.8 6.9 0.18 12.1 0.5 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4634) Cmc1 PF08583.10 KSA04216.1 - 0.066 13.2 0.2 0.081 13.0 0.2 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like TRP PF06011.12 KSA04217.1 - 1.6e-93 313.8 12.2 1.6e-74 251.2 8.2 2.1 1 1 1 2 2 2 2 Transient receptor potential (TRP) ion channel EphA2_TM PF14575.6 KSA04217.1 - 0.39 11.6 2.0 11 7.0 0.0 3.8 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain DUF202 PF02656.15 KSA04217.1 - 2.7 8.5 11.0 8.3 6.9 0.0 4.6 5 0 0 5 5 5 0 Domain of unknown function (DUF202) SET PF00856.28 KSA04218.1 - 2.3e-21 76.9 0.4 4.2e-21 76.1 0.1 1.6 2 0 0 2 2 2 1 SET domain DUF3219 PF11514.8 KSA04218.1 - 0.0033 17.4 0.1 0.013 15.5 0.1 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3219) ABC2_membrane_3 PF12698.7 KSA04218.1 - 0.12 11.5 0.7 0.22 10.6 0.7 1.4 1 0 0 1 1 1 0 ABC-2 family transporter protein WD40 PF00400.32 KSA04219.1 - 5e-09 36.6 0.4 0.12 13.3 0.0 5.9 7 0 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KSA04219.1 - 5.3e-05 23.5 0.0 5.4 7.4 0.0 4.9 1 1 4 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KSA04219.1 - 0.00018 21.0 0.3 0.0042 16.5 0.1 2.3 1 1 1 2 2 2 2 WD40-like domain PQQ_3 PF13570.6 KSA04219.1 - 0.029 14.9 0.0 32 5.2 0.0 3.7 4 0 0 4 4 4 0 PQQ-like domain LRR_4 PF12799.7 KSA04219.1 - 0.25 11.8 2.6 0.43 11.1 0.4 2.5 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) WHEP-TRS PF00458.20 KSA04220.1 - 0.11 12.7 0.2 0.21 11.8 0.2 1.3 1 0 0 1 1 1 0 WHEP-TRS domain F_actin_bind PF08919.10 KSA04221.1 - 0.025 14.7 0.1 0.13 12.4 0.1 2.3 1 0 0 1 1 1 0 F-actin binding Serglycin PF04360.12 KSA04221.1 - 0.21 11.5 6.1 0.12 12.3 2.2 2.5 2 0 0 2 2 2 0 Serglycin Foie-gras_1 PF11817.8 KSA04221.1 - 0.72 9.4 2.3 0.65 9.5 0.2 1.8 2 0 0 2 2 2 0 Foie gras liver health family 1 Pkinase PF00069.25 KSA04222.1 - 3.6e-38 131.5 0.0 6.7e-38 130.6 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KSA04222.1 - 2.2e-20 73.1 0.0 3.1e-14 52.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase LRR_4 PF12799.7 KSA04223.1 - 0.0084 16.5 4.4 0.0084 16.5 4.4 5.4 4 1 0 4 4 4 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KSA04223.1 - 0.36 10.6 22.5 0.047 13.5 6.0 4.3 4 2 1 5 5 4 0 Leucine rich repeat Med14 PF08638.11 KSA04224.1 - 7.7e-56 188.5 0.1 2.9e-55 186.6 0.1 2.1 1 0 0 1 1 1 1 Mediator complex subunit MED14 Zn_clus PF00172.18 KSA04225.1 - 1.6e-07 31.3 30.9 0.0003 20.9 2.5 3.3 3 0 0 3 3 3 3 Fungal Zn(2)-Cys(6) binuclear cluster domain NUDE_C PF04880.13 KSA04225.1 - 0.91 10.0 16.1 0.3 11.5 8.6 2.2 2 0 0 2 2 2 0 NUDE protein, C-terminal conserved region Aldose_epim PF01263.20 KSA04227.1 - 1.2e-44 152.9 0.1 1.5e-44 152.6 0.1 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase PAP2_3 PF14378.6 KSA04228.1 - 3.4e-24 85.6 11.5 3.4e-24 85.6 11.5 2.1 2 0 0 2 2 2 1 PAP2 superfamily PAP2 PF01569.21 KSA04228.1 - 5.5e-09 35.9 10.2 5.5e-09 35.9 10.2 2.3 2 1 0 2 2 2 1 PAP2 superfamily Ribosomal_S6 PF01250.17 KSA04229.1 - 4e-26 91.1 0.0 4.9e-26 90.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 DUF5499 PF17603.2 KSA04229.1 - 0.14 12.8 0.0 0.16 12.6 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5499) APS_kinase PF01583.20 KSA04230.1 - 3.7e-71 238.1 0.0 4.6e-71 237.8 0.0 1.0 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 KSA04230.1 - 4.2e-05 23.7 0.0 7.5e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 KSA04230.1 - 0.00074 19.0 0.0 0.00085 18.8 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_18 PF13238.6 KSA04230.1 - 0.0017 18.9 0.1 0.0032 18.0 0.1 1.6 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KSA04230.1 - 0.0026 17.1 0.0 0.0039 16.5 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_29 PF13555.6 KSA04230.1 - 0.019 14.7 0.0 0.031 14.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 KSA04230.1 - 0.034 14.5 0.1 0.058 13.8 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain CPT PF07931.12 KSA04230.1 - 0.14 12.0 0.2 1.2 8.9 0.2 2.0 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein CbiA PF01656.23 KSA04230.1 - 0.17 12.0 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Snf7 PF03357.21 KSA04231.1 - 4.1e-30 104.6 28.0 2.8e-29 101.9 25.2 2.0 2 0 0 2 2 2 1 Snf7 Ist1 PF03398.14 KSA04231.1 - 0.0005 20.0 6.9 0.00074 19.5 6.9 1.3 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Uds1 PF15456.6 KSA04231.1 - 0.007 16.5 1.6 0.007 16.5 1.6 2.3 1 1 0 2 2 2 1 Up-regulated During Septation RNA_pol_Rpb1_5 PF04998.17 KSA04231.1 - 0.14 11.6 1.1 0.16 11.4 1.1 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 DAO PF01266.24 KSA04232.1 - 8.1e-27 94.7 0.0 9.3e-27 94.5 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Cu-oxidase_2 PF07731.14 KSA04233.1 - 1.5e-49 167.3 7.1 8e-42 142.2 1.3 3.7 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KSA04233.1 - 4.8e-44 149.2 3.3 2.2e-42 143.8 0.1 2.8 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 KSA04233.1 - 6.1e-35 120.7 7.4 1.4e-31 109.7 0.5 3.4 3 1 0 3 3 3 2 Multicopper oxidase DUF5082 PF16888.5 KSA04235.1 - 0.0028 17.9 3.9 0.0028 17.9 3.9 4.0 2 1 1 3 3 3 1 Domain of unknown function (DUF5082) ADIP PF11559.8 KSA04235.1 - 0.018 15.1 13.6 0.018 15.1 13.6 3.4 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Atg14 PF10186.9 KSA04235.1 - 0.028 13.5 30.5 0.36 9.9 13.1 2.3 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Styelin PF17562.2 KSA04235.1 - 0.17 12.3 4.0 0.3 11.5 3.3 1.8 1 1 0 1 1 1 0 Styelin Tup_N PF08581.10 KSA04235.1 - 0.2 12.0 20.2 0.2 12.0 1.8 3.5 2 1 1 3 3 3 0 Tup N-terminal YabA PF06156.13 KSA04235.1 - 1.2 9.9 33.1 0.2 12.3 8.3 4.1 2 1 1 3 3 3 0 Initiation control protein YabA DUF4407 PF14362.6 KSA04235.1 - 6.3 6.1 16.2 0.82 9.0 7.6 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Tropomyosin PF00261.20 KSA04235.1 - 6.9 6.0 32.3 0.093 12.1 1.6 3.5 2 1 0 3 3 3 0 Tropomyosin TPR_MLP1_2 PF07926.12 KSA04235.1 - 7.7 6.6 40.0 0.031 14.3 21.2 3.7 4 1 0 4 4 4 0 TPR/MLP1/MLP2-like protein Myb_DNA-binding PF00249.31 KSA04236.1 - 6.7e-19 67.8 11.2 2.9e-10 40.2 0.6 3.5 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KSA04236.1 - 3.4e-18 65.6 6.3 2.6e-10 40.4 0.3 3.2 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 KSA04236.1 - 3.2e-07 30.6 7.7 1.7e-06 28.3 0.8 3.5 2 1 1 3 3 3 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 KSA04236.1 - 6.9 7.1 14.6 1.6 9.1 0.3 4.2 3 1 1 4 4 4 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Sec5 PF15469.6 KSA04237.1 - 1.1e-47 162.3 18.5 1.1e-47 162.3 18.5 2.8 2 1 1 3 3 3 1 Exocyst complex component Sec5 Vps51 PF08700.11 KSA04237.1 - 1.9e-06 27.9 0.9 1.9e-06 27.9 0.9 3.4 4 0 0 4 4 4 1 Vps51/Vps67 FTR1 PF03239.14 KSA04238.1 - 1e-89 300.8 6.4 1.2e-89 300.5 6.4 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family DUF1772 PF08592.11 KSA04238.1 - 0.15 12.4 0.9 1.6 9.0 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) MgtE PF01769.16 KSA04238.1 - 2.4 8.5 17.4 1.3 9.4 3.0 3.0 3 0 0 3 3 3 0 Divalent cation transporter DUF3180 PF11377.8 KSA04238.1 - 4.8 7.3 7.6 5.4 7.2 0.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3180) WD40 PF00400.32 KSA04239.1 - 0.00052 20.8 12.7 2.8 9.0 0.8 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat DUF3289 PF11692.8 KSA04239.1 - 0.036 13.7 0.0 0.067 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3289) SHE3 PF17078.5 KSA04240.1 - 3.9e-62 209.9 32.4 3.9e-62 209.9 32.4 1.9 2 0 0 2 2 2 1 SWI5-dependent HO expression protein 3 GAS PF13851.6 KSA04240.1 - 0.0024 17.2 9.8 0.0024 17.2 9.8 3.9 2 1 2 4 4 4 2 Growth-arrest specific micro-tubule binding DUF3552 PF12072.8 KSA04240.1 - 0.01 15.3 5.8 0.01 15.3 5.8 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF3552) Tup_N PF08581.10 KSA04240.1 - 0.02 15.2 14.2 0.15 12.4 4.3 3.8 1 1 1 3 3 3 0 Tup N-terminal Suppressor_APC PF11414.8 KSA04240.1 - 0.021 14.9 1.5 0.059 13.4 0.1 2.5 2 0 0 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein SlyX PF04102.12 KSA04240.1 - 0.19 12.4 4.9 68 4.2 0.0 4.4 4 0 0 4 4 4 0 SlyX HALZ PF02183.18 KSA04240.1 - 0.49 10.7 15.3 10 6.4 0.3 4.7 3 2 2 5 5 5 0 Homeobox associated leucine zipper Golgin_A5 PF09787.9 KSA04240.1 - 0.58 9.6 27.5 0.066 12.7 19.1 3.0 2 1 0 2 2 2 0 Golgin subfamily A member 5 FRP PF18032.1 KSA04240.1 - 0.67 10.6 6.5 0.22 12.1 2.2 2.5 2 1 0 2 2 2 0 Photoprotection regulator fluorescence recovery protein DUF3450 PF11932.8 KSA04240.1 - 0.85 8.9 16.8 3.9 6.7 4.5 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) ERM PF00769.19 KSA04240.1 - 5.2 6.8 29.1 0.0097 15.7 14.8 2.7 2 1 0 3 3 3 0 Ezrin/radixin/moesin family Jnk-SapK_ap_N PF09744.9 KSA04240.1 - 8.4 6.6 24.7 0.046 13.9 6.7 3.5 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Debaryomyces_fabryi-debFab1.0/GCA_001447935.1_debFab1.0_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Debaryomyces_fabryi-debFab1.0/GCA_001447935.1_debFab1.0_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Debaryomyces_fabryi-debFab1.0/GCA_001447935.1_debFab1.0_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Debaryomyces_fabryi-debFab1.0/GCA_001447935.1_debFab1.0_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Sun Mar 24 18:06:25 2019 # [ok]