# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Zn_clus PF00172.18 KIY60528.1 - 2.7 8.2 10.9 1 9.5 1.5 2.5 1 1 1 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Bcl-2_BAD PF10514.9 KIY60528.1 - 9.6 6.7 11.2 3.1 8.3 1.1 2.1 2 0 0 2 2 2 0 Pro-apoptotic Bcl-2 protein, BAD KSHV_K1 PF11049.8 KIY60529.1 - 0.0074 16.2 0.1 0.013 15.4 0.1 1.3 1 0 0 1 1 1 1 Glycoprotein K1 of Kaposi's sarcoma-associated herpes virus DDE_3 PF13358.6 KIY60534.1 - 1.7e-06 27.8 0.0 3.5e-06 26.8 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_29 PF13551.6 KIY60534.1 - 8.6e-05 22.5 0.0 0.00062 19.7 0.0 2.2 2 0 0 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.6 KIY60534.1 - 8.7e-05 22.2 0.2 0.00026 20.7 0.2 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KIY60534.1 - 0.00023 21.2 0.1 0.00073 19.6 0.1 2.0 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_7 PF02796.15 KIY60534.1 - 0.00046 20.2 0.0 0.002 18.1 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_32 PF13565.6 KIY60534.1 - 0.0069 17.0 0.9 0.063 13.9 0.3 2.3 1 1 1 2 2 2 2 Homeodomain-like domain HTH_38 PF13936.6 KIY60534.1 - 0.032 14.0 0.0 0.073 12.9 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Terminase_5 PF06056.12 KIY60534.1 - 0.05 13.5 0.0 0.096 12.6 0.0 1.6 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) HTH_19 PF12844.7 KIY60534.1 - 0.15 12.1 0.1 3 7.9 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Tnp_IS630 PF01710.16 KIY60534.1 - 0.24 11.5 0.0 0.3 11.2 0.0 1.3 1 0 0 1 1 1 0 Transposase Leu_zip PF15294.6 KIY60535.1 - 0.017 14.7 1.4 0.02 14.4 1.4 1.1 1 0 0 1 1 1 0 Leucine zipper XhlA PF10779.9 KIY60535.1 - 0.28 11.4 1.5 0.31 11.3 0.4 1.6 1 1 1 2 2 2 0 Haemolysin XhlA DivIC PF04977.15 KIY60535.1 - 0.44 10.3 3.5 3.4 7.5 1.8 2.2 2 0 0 2 2 2 0 Septum formation initiator Metal_resist PF13801.6 KIY60535.1 - 2.7 8.2 11.4 2.7 8.2 10.1 1.7 1 1 0 1 1 1 0 Heavy-metal resistance CxC2 PF18803.1 KIY60538.1 - 8.7e-21 74.1 0.0 1.8e-20 73.1 0.0 1.5 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases KDZ PF18758.1 KIY60538.1 - 2.9e-11 43.4 0.0 3.7e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 KIY60538.1 - 0.012 15.7 0.1 0.05 13.8 0.0 1.9 2 0 0 2 2 2 0 CxC1 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 KIY60538.1 - 0.022 14.6 0.0 0.05 13.4 0.0 1.6 1 0 0 1 1 1 0 CxC3 like cysteine cluster associated with KDZ transposases Dec-1 PF04624.14 KIY60541.1 - 0.065 13.1 0.3 0.097 12.5 0.3 1.2 1 0 0 1 1 1 0 Dec-1 repeat DUF2827 PF10933.8 KIY60542.1 - 0.18 10.5 0.0 0.23 10.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2827) Cauli_VI PF01693.16 KIY60543.1 - 1.3e-05 25.4 3.0 4.2e-05 23.7 0.4 2.7 2 1 1 3 3 3 2 Caulimovirus viroplasmin T2SSG PF08334.11 KIY60545.1 - 0.13 12.3 0.0 0.15 12.1 0.0 1.1 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein G Zn_clus PF00172.18 KIY60546.1 - 0.00096 19.2 7.1 0.0014 18.7 7.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 5_nucleotid PF05761.14 KIY60546.1 - 0.013 14.5 0.7 0.016 14.2 0.7 1.0 1 0 0 1 1 1 0 5' nucleotidase family TBCA PF02970.16 KIY60546.1 - 0.12 12.7 5.8 2.9 8.3 5.8 2.3 1 1 0 1 1 1 0 Tubulin binding cofactor A KDZ PF18758.1 KIY60547.1 - 1.2e-32 113.4 0.0 1.4e-32 113.1 0.0 1.1 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase BLOC1_2 PF10046.9 KIY60551.1 - 0.11 12.8 0.2 0.19 12.1 0.2 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Prefoldin_2 PF01920.20 KIY60551.1 - 0.22 11.5 1.3 0.37 10.8 1.3 1.2 1 0 0 1 1 1 0 Prefoldin subunit YtxH PF12732.7 KIY60553.1 - 6.7 7.3 6.1 26 5.5 0.8 2.7 2 1 0 2 2 2 0 YtxH-like protein Nop25 PF09805.9 KIY60555.1 - 0.011 16.2 4.2 0.011 16.2 4.2 2.0 2 1 0 2 2 2 0 Nucleolar protein 12 (25kDa) DUF1003 PF06210.11 KIY60555.1 - 1.9 8.6 3.0 3.4 7.8 3.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) MAJIN PF15077.6 KIY60555.1 - 2.2 8.0 10.6 0.38 10.5 0.5 2.1 2 0 0 2 2 2 0 Membrane-anchored junction protein MFAP1 PF06991.11 KIY60555.1 - 4.2 7.2 16.0 0.37 10.6 11.1 1.7 2 0 0 2 2 2 0 Microfibril-associated/Pre-mRNA processing COPI_C PF06957.11 KIY60555.1 - 6.6 5.4 11.4 9.7 4.8 11.4 1.2 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus PHBC_N PF12551.8 KIY60557.1 - 0.32 10.8 2.6 3.7 7.4 0.2 2.6 2 0 0 2 2 2 0 Poly-beta-hydroxybutyrate polymerase N terminal SNF2_N PF00176.23 KIY60558.1 - 1.4e-10 40.4 0.0 1.6e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain SNF2_N PF00176.23 KIY60562.1 - 0.00049 18.9 0.0 0.00075 18.3 0.0 1.4 1 1 0 1 1 1 1 SNF2 family N-terminal domain Plavaka PF18759.1 KIY60563.1 - 6.9e-68 229.3 0.0 7.6e-68 229.1 0.0 1.0 1 0 0 1 1 1 1 Plavaka transposase Plavaka PF18759.1 KIY60564.1 - 5.4e-16 58.7 0.7 6.2e-16 58.5 0.7 1.1 1 0 0 1 1 1 1 Plavaka transposase RasGAP PF00616.19 KIY60568.1 - 9.1e-15 54.9 0.0 1.1e-14 54.7 0.0 1.1 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase KDZ PF18758.1 KIY60570.1 - 3.4e-35 121.7 0.0 4.5e-35 121.3 0.0 1.2 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KIY60570.1 - 3.3e-10 40.1 1.2 5.5e-10 39.4 0.1 1.9 2 0 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases Thymidylat_synt PF00303.19 KIY60573.1 - 0.53 9.4 2.6 0.64 9.1 2.6 1.1 1 0 0 1 1 1 0 Thymidylate synthase TTSSLRR PF12468.8 KIY60573.1 - 0.64 10.3 6.0 0.87 9.9 0.2 2.8 3 0 0 3 3 3 0 Type III secretion system leucine rich repeat protein AT_hook PF02178.19 KIY60574.1 - 0.13 12.2 0.6 0.26 11.3 0.6 1.5 1 0 0 1 1 1 0 AT hook motif EMP24_GP25L PF01105.24 KIY60574.1 - 0.31 11.0 1.0 0.42 10.5 0.2 1.5 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD RVT_1 PF00078.27 KIY60575.1 - 0.019 14.5 0.0 0.02 14.4 0.0 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) FAR1 PF03101.15 KIY60576.1 - 0.0017 19.0 0.1 0.0044 17.7 0.1 1.6 1 0 0 1 1 1 1 FAR1 DNA-binding domain STN PF07660.14 KIY60586.1 - 0.072 12.9 0.2 8 6.4 0.0 2.3 2 0 0 2 2 2 0 Secretin and TonB N terminus short domain Nab2 PF11517.8 KIY60586.1 - 0.13 12.5 0.0 0.32 11.3 0.0 1.7 1 0 0 1 1 1 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) Zn_clus PF00172.18 KIY60595.1 - 0.0074 16.4 1.3 0.013 15.6 1.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cnd1_N PF12922.7 KIY60595.1 - 0.09 12.6 0.5 0.11 12.4 0.5 1.1 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term Plavaka PF18759.1 KIY60598.1 - 1.7e-63 214.9 0.0 1.9e-63 214.7 0.0 1.0 1 0 0 1 1 1 1 Plavaka transposase Mucin PF01456.17 KIY60603.1 - 0.33 11.0 7.1 0.41 10.6 7.1 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein RR_TM4-6 PF06459.12 KIY60605.1 - 0.0082 16.0 4.2 0.011 15.6 3.6 1.5 1 1 0 1 1 1 1 Ryanodine Receptor TM 4-6 RT_RNaseH_2 PF17919.1 KIY60606.1 - 3.3e-06 27.1 0.0 4.6e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KIY60606.1 - 3.5e-05 24.0 0.0 4.7e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase FAP PF07174.11 KIY60612.1 - 0.026 14.0 12.1 0.028 13.9 12.1 1.0 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) CCDC53 PF10152.9 KIY60615.1 - 0.029 14.8 0.7 0.039 14.4 0.7 1.2 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF4106 PF13388.6 KIY60615.1 - 0.2 10.8 9.2 0.27 10.4 9.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) CxC2 PF18803.1 KIY60617.1 - 9e-30 103.0 0.7 9e-30 103.0 0.7 1.7 2 0 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KIY60617.1 - 9.2e-06 25.8 0.4 9.2e-06 25.8 0.4 1.8 2 1 1 3 3 3 1 CxC1 like cysteine cluster associated with KDZ transposases Exonuc_X-T_C PF08411.10 KIY60618.1 - 0.076 12.1 0.0 0.085 12.0 0.0 1.0 1 0 0 1 1 1 0 Exonuclease C-terminal Plavaka PF18759.1 KIY60620.1 - 1e-86 291.1 0.1 1.3e-86 290.8 0.1 1.1 1 0 0 1 1 1 1 Plavaka transposase AKAP95 PF04988.12 KIY60621.1 - 0.09 13.0 1.8 0.12 12.7 0.1 1.9 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) Rootletin PF15035.6 KIY60622.1 - 0.021 14.8 1.3 0.03 14.3 1.3 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion LSR PF05624.14 KIY60624.1 - 5 7.2 11.4 0.53 10.3 5.7 2.2 2 0 0 2 2 2 0 Lipolysis stimulated receptor (LSR) tRNA_anti-codon PF01336.25 KIY60625.1 - 0.0031 17.5 0.1 0.0042 17.0 0.1 1.2 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Pkinase PF00069.25 KIY60629.1 - 0.0061 16.0 0.0 0.063 12.6 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY60629.1 - 0.13 11.5 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Plavaka PF18759.1 KIY60631.1 - 3.5e-42 144.8 1.8 4.5e-42 144.4 1.8 1.1 1 0 0 1 1 1 1 Plavaka transposase SNF2_N PF00176.23 KIY60632.1 - 0.035 12.8 0.1 0.055 12.2 0.1 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain DUF1244 PF06844.11 KIY60633.1 - 9.3 6.5 7.2 4.3 7.6 0.4 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1244) Integrase_H2C2 PF17921.1 KIY60634.1 - 3.1e-08 33.6 0.3 3.6e-08 33.4 0.3 1.1 1 0 0 1 1 1 1 Integrase zinc binding domain Pro_isomerase PF00160.21 KIY60640.1 - 4.6e-23 82.2 0.0 3e-22 79.6 0.0 1.8 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-CCHC_5 PF14787.6 KIY60641.1 - 0.0046 16.6 3.5 0.0099 15.6 3.5 1.6 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.6 KIY60641.1 - 0.058 13.2 2.8 0.12 12.3 2.8 1.5 1 0 0 1 1 1 0 Zinc knuckle PSCyt3 PF07627.11 KIY60641.1 - 0.075 13.3 0.0 2.8 8.3 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1588) zf-CCHC PF00098.23 KIY60641.1 - 0.12 12.5 2.0 0.26 11.4 2.0 1.6 1 0 0 1 1 1 0 Zinc knuckle WD40 PF00400.32 KIY60643.1 - 0.17 12.8 0.0 0.27 12.2 0.0 1.4 1 0 0 1 1 1 0 WD domain, G-beta repeat zf-RVT PF13966.6 KIY60644.1 - 3e-05 24.7 4.3 3e-05 24.7 4.3 1.9 2 1 0 2 2 2 1 zinc-binding in reverse transcriptase DUF2768 PF10966.8 KIY60645.1 - 0.16 12.4 2.6 0.94 10.0 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2768) F-box-like PF12937.7 KIY60646.1 - 1.8e-06 27.7 0.2 5.1e-06 26.3 0.2 1.8 1 0 0 1 1 1 1 F-box-like PQQ PF01011.21 KIY60650.1 - 0.0079 16.1 2.4 0.019 14.9 0.1 2.7 2 1 1 3 3 3 1 PQQ enzyme repeat Phage_int_SAM_1 PF02899.17 KIY60653.1 - 0.18 12.2 0.0 0.22 11.9 0.0 1.1 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Plavaka PF18759.1 KIY60654.1 - 9.3e-94 314.3 0.4 1.3e-93 313.8 0.4 1.2 1 0 0 1 1 1 1 Plavaka transposase DUF4218 PF13960.6 KIY60655.1 - 0.0002 20.9 0.0 0.00022 20.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) T2SSE_N PF05157.15 KIY60656.1 - 0.013 15.8 0.0 0.031 14.6 0.0 1.6 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein E, N-terminal domain Transposase_21 PF02992.14 KIY60656.1 - 0.33 10.2 1.3 0.85 8.8 0.0 2.2 3 0 0 3 3 3 0 Transposase family tnp2 Sugarporin_N PF11471.8 KIY60661.1 - 0.037 14.0 0.0 0.046 13.7 0.0 1.2 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Fungal_trans PF04082.18 KIY60662.1 - 2.6e-07 29.9 0.0 3.2e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pkinase PF00069.25 KIY60663.1 - 0.019 14.4 0.0 0.027 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Pkinase_Tyr PF07714.17 KIY60663.1 - 0.2 10.9 0.0 0.29 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase DUF3644 PF12358.8 KIY60664.1 - 0.1 13.1 0.2 22 5.6 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3644) zf-C2HC PF01530.18 KIY60668.1 - 3.9 7.8 16.6 9.7 6.5 1.4 4.5 2 2 2 4 4 4 0 Zinc finger, C2HC type zf-MYND PF01753.18 KIY60670.1 - 2.7e-06 27.4 11.1 6.8e-06 26.1 11.1 1.8 1 1 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 KIY60670.1 - 0.088 12.9 4.8 0.23 11.6 4.8 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 DUF5122 PF17164.4 KIY60671.1 - 0.08 13.2 0.0 0.18 12.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5122) beta-propeller HLH PF00010.26 KIY60672.1 - 2.3e-06 27.4 0.0 1.3e-05 25.1 0.0 2.2 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DMAP1_like PF17024.5 KIY60676.1 - 0.014 15.6 0.0 0.018 15.2 0.0 1.2 1 0 0 1 1 1 0 Putative DMAP1-like Plavaka PF18759.1 KIY60684.1 - 2.4e-55 188.0 0.2 3.2e-55 187.6 0.2 1.2 1 0 0 1 1 1 1 Plavaka transposase Endonuc-FokI_C PF09254.11 KIY60687.1 - 0.017 14.4 0.1 0.021 14.1 0.1 1.1 1 0 0 1 1 1 0 Restriction endonuclease FokI, C terminal Peptidase_S10 PF00450.22 KIY60691.1 - 6.6e-65 220.1 2.1 8.4e-65 219.8 2.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Corona_6B_7B PF03262.13 KIY60691.1 - 0.065 12.7 0.3 0.49 9.8 0.0 2.3 3 0 0 3 3 3 0 Coronavirus 6B/7B protein Tau95 PF09734.9 KIY60692.1 - 0.00025 21.9 0.1 0.00042 21.1 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain DUF5431 PF17496.2 KIY60692.1 - 0.036 14.2 0.0 0.072 13.2 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5431) GATA PF00320.27 KIY60693.1 - 8.1 6.1 11.4 0.73 9.5 3.5 2.8 2 1 0 2 2 2 0 GATA zinc finger DDE_1 PF03184.19 KIY60695.1 - 1.6e-20 73.5 0.0 2e-20 73.1 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KIY60695.1 - 1.5e-07 31.3 0.0 0.0025 17.6 0.0 2.1 2 0 0 2 2 2 2 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KIY60696.1 - 5.7e-06 26.3 0.0 8.1e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DUF4562 PF15123.6 KIY60698.1 - 0.036 14.0 0.3 0.051 13.5 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4562) Zn_clus PF00172.18 KIY60699.1 - 0.012 15.7 8.5 0.033 14.3 2.6 2.4 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain PSCyt3 PF07627.11 KIY60699.1 - 4.3 7.7 7.5 1.1 9.6 1.4 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1588) zf-CCHC PF00098.23 KIY60701.1 - 0.00056 19.9 1.8 0.00056 19.9 1.8 1.9 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_4 PF14392.6 KIY60701.1 - 0.0034 17.1 0.6 0.0034 17.1 0.6 2.3 3 0 0 3 3 3 1 Zinc knuckle Chromo PF00385.24 KIY60704.1 - 3.1e-08 33.4 0.1 3.4e-08 33.3 0.1 1.0 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Cullin PF00888.22 KIY60706.1 - 1.3e-28 100.0 0.1 2.2e-28 99.3 0.1 1.3 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KIY60706.1 - 1.6e-21 76.1 0.1 3.3e-21 75.1 0.1 1.5 1 0 0 1 1 1 1 Cullin protein neddylation domain DUF962 PF06127.11 KIY60706.1 - 0.035 14.2 0.0 0.047 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF962) NtA PF03146.15 KIY60706.1 - 0.074 12.9 0.2 0.13 12.2 0.2 1.4 1 0 0 1 1 1 0 Agrin NtA domain rve_3 PF13683.6 KIY60706.1 - 0.11 12.3 0.1 0.25 11.2 0.1 1.6 1 0 0 1 1 1 0 Integrase core domain Cullin PF00888.22 KIY60708.1 - 7.7e-36 123.9 0.0 1.2e-35 123.2 0.0 1.3 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KIY60708.1 - 2e-21 75.8 0.1 4.5e-21 74.7 0.1 1.6 1 0 0 1 1 1 1 Cullin protein neddylation domain rve_3 PF13683.6 KIY60708.1 - 0.043 13.6 0.0 0.096 12.5 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain NtA PF03146.15 KIY60708.1 - 0.087 12.7 0.2 0.15 11.9 0.2 1.4 1 0 0 1 1 1 0 Agrin NtA domain DUF962 PF06127.11 KIY60708.1 - 0.14 12.3 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF962) Helitron_like_N PF14214.6 KIY60710.1 - 3e-09 37.4 0.1 6.5e-08 33.0 0.0 2.3 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus Helitron_like_N PF14214.6 KIY60711.1 - 5e-11 43.2 0.0 6.6e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Cauli_VI PF01693.16 KIY60714.1 - 2.6e-20 72.4 1.2 1.5e-09 38.0 0.3 2.5 2 0 0 2 2 2 2 Caulimovirus viroplasmin F-box-like PF12937.7 KIY60716.1 - 0.0017 18.2 0.6 0.0047 16.8 0.1 2.0 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 KIY60719.1 - 1.4e-07 31.3 1.3 3.8e-07 29.9 1.3 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY60719.1 - 0.059 13.3 1.9 0.31 11.0 1.9 2.2 1 1 0 1 1 1 0 F-box domain CxC2 PF18803.1 KIY60722.1 - 8.2e-30 103.1 0.3 2.9e-29 101.3 0.0 1.9 2 0 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases KDZ PF18758.1 KIY60722.1 - 4.3e-22 78.8 0.0 6.2e-22 78.3 0.0 1.2 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 KIY60722.1 - 0.18 12.0 1.3 0.19 11.9 0.1 1.6 2 0 0 2 2 2 0 CxC1 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 KIY60722.1 - 0.24 11.3 0.0 0.24 11.3 0.0 2.2 2 0 0 2 2 2 0 CxC3 like cysteine cluster associated with KDZ transposases RNA_pol_Rpa2_4 PF06883.12 KIY60726.1 - 0.048 13.7 0.1 0.088 12.8 0.1 1.4 1 0 0 1 1 1 0 RNA polymerase I, Rpa2 specific domain MULE PF10551.9 KIY60731.1 - 1.2e-12 48.1 0.6 2e-12 47.3 0.6 1.4 1 0 0 1 1 1 1 MULE transposase domain DUF3320 PF11784.8 KIY60732.1 - 0.059 13.3 0.1 7.4 6.6 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3320) RT_RNaseH PF17917.1 KIY60738.1 - 0.00021 21.5 0.0 0.00027 21.2 0.0 1.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KIY60741.1 - 0.00021 21.5 0.0 0.00027 21.2 0.0 1.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase F-box-like PF12937.7 KIY60742.1 - 3.4e-09 36.4 1.6 3.4e-09 36.4 1.6 1.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIY60742.1 - 0.00017 21.3 0.5 0.00017 21.3 0.5 2.0 2 1 0 2 2 2 1 F-box domain CorA PF01544.18 KIY60742.1 - 0.0015 17.9 0.1 0.0019 17.6 0.1 1.0 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF758 PF05527.11 KIY60742.1 - 0.019 15.0 0.1 0.024 14.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF758) F-box-like_2 PF13013.6 KIY60742.1 - 0.04 13.9 0.9 0.1 12.6 0.6 2.0 1 1 1 2 2 2 0 F-box-like domain Tektin PF03148.14 KIY60742.1 - 0.064 12.0 0.2 0.083 11.6 0.2 1.1 1 0 0 1 1 1 0 Tektin family IFP_35_N PF07334.13 KIY60742.1 - 0.067 13.3 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus ADIP PF11559.8 KIY60742.1 - 0.078 13.1 0.1 0.1 12.7 0.1 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Utp13 PF08625.11 KIY60742.1 - 0.08 12.8 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 Utp13 specific WD40 associated domain Snf7 PF03357.21 KIY60742.1 - 0.08 12.5 0.1 0.098 12.2 0.1 1.1 1 0 0 1 1 1 0 Snf7 LRR_4 PF12799.7 KIY60743.1 - 0.051 14.0 1.3 5.7 7.5 0.1 3.2 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) DEAD PF00270.29 KIY60744.1 - 7.6e-08 32.3 0.0 1.3e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIY60744.1 - 4.4e-07 30.2 0.0 1.1e-06 28.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIY60744.1 - 0.0016 18.5 0.0 0.0036 17.3 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_16 PF13191.6 KIY60744.1 - 0.1 13.0 0.1 0.66 10.3 0.1 2.4 2 1 0 2 2 2 0 AAA ATPase domain APH PF01636.23 KIY60745.1 - 7.4e-05 22.8 0.2 0.075 12.9 0.1 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.25 KIY60745.1 - 0.00024 20.6 0.0 0.00026 20.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain WaaY PF06176.11 KIY60745.1 - 0.0047 16.6 0.0 0.0051 16.5 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) Choline_kinase PF01633.20 KIY60745.1 - 0.054 13.1 0.0 0.06 12.9 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase FTO_NTD PF12933.7 KIY60745.1 - 0.071 12.3 0.0 0.094 11.9 0.0 1.1 1 0 0 1 1 1 0 FTO catalytic domain OrsD PF12013.8 KIY60747.1 - 3e-06 27.6 0.2 7.1e-06 26.4 0.2 1.7 1 0 0 1 1 1 1 Orsellinic acid/F9775 biosynthesis cluster protein D AKAP95 PF04988.12 KIY60747.1 - 0.78 10.0 3.7 0.5 10.6 0.3 2.1 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) KASH_CCD PF14662.6 KIY60748.1 - 0.014 15.2 0.5 0.018 14.9 0.5 1.1 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH XRCC4 PF06632.12 KIY60748.1 - 0.085 11.7 1.3 0.11 11.3 1.3 1.1 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 UL73_N PF12522.8 KIY60751.1 - 0.069 12.9 1.1 0.088 12.6 1.1 1.1 1 0 0 1 1 1 0 Cytomegalovirus glycoprotein N terminal DUF659 PF04937.15 KIY60751.1 - 0.078 12.8 0.0 0.084 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF 659) DUF3008 PF11450.8 KIY60754.1 - 0.13 12.5 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknwon function (DUF3008) BNR PF02012.20 KIY60754.1 - 0.13 12.4 0.2 0.3 11.3 0.2 1.6 1 0 0 1 1 1 0 BNR/Asp-box repeat PRIMA1 PF16101.5 KIY60757.1 - 0.37 10.8 5.6 0.37 10.9 5.6 1.2 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Mito_fiss_reg PF05308.11 KIY60757.1 - 1.3 9.1 4.4 1.1 9.3 4.4 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 KIY60757.1 - 1.7 8.1 7.5 1.6 8.1 7.5 1.0 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal RT_RNaseH_2 PF17919.1 KIY60759.1 - 2.7e-08 33.8 0.0 3.1e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase T3SSipB PF16535.5 KIY60761.1 - 0.66 10.4 5.2 1.3 9.5 5.2 1.6 1 1 0 1 1 1 0 Type III cell invasion protein SipB Asp_protease_2 PF13650.6 KIY60762.1 - 0.0032 18.1 0.0 0.0043 17.7 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KIY60762.1 - 0.037 14.6 0.0 0.047 14.2 0.0 1.2 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF1631 PF07793.11 KIY60765.1 - 0.13 10.7 7.7 0.16 10.4 7.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) QWRF PF04484.12 KIY60765.1 - 0.15 11.8 2.3 0.2 11.4 2.3 1.1 1 0 0 1 1 1 0 QWRF family DUF908 PF06012.12 KIY60765.1 - 0.33 10.3 2.3 0.38 10.1 2.3 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) FAP PF07174.11 KIY60765.1 - 0.35 10.3 16.5 0.36 10.3 16.5 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Hamartin PF04388.12 KIY60765.1 - 3.1 6.4 5.0 2.6 6.6 5.0 1.1 1 0 0 1 1 1 0 Hamartin protein Bul1_C PF04426.12 KIY60766.1 - 0.065 12.6 0.3 0.11 11.8 0.0 1.6 2 0 0 2 2 2 0 Bul1 C terminus SRA1 PF07304.11 KIY60767.1 - 0.016 15.0 0.3 0.03 14.1 0.3 1.4 1 0 0 1 1 1 0 Steroid receptor RNA activator (SRA1) PPP4R2 PF09184.11 KIY60767.1 - 1.3 8.5 16.4 2 7.9 16.4 1.2 1 0 0 1 1 1 0 PPP4R2 SDA1 PF05285.12 KIY60767.1 - 4.4 6.6 24.2 5.9 6.2 24.2 1.2 1 0 0 1 1 1 0 SDA1 GPI-anchored PF10342.9 KIY60769.1 - 2.5e-07 31.3 0.2 3.6e-07 30.8 0.2 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF3597 PF12200.8 KIY60770.1 - 0.088 13.3 0.1 0.13 12.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3597) Occludin_ELL PF07303.13 KIY60771.1 - 0.063 14.0 0.7 0.3 11.8 0.1 2.0 1 1 1 2 2 2 0 Occludin homology domain Endonuc_Holl PF10107.9 KIY60771.1 - 0.34 10.7 3.0 0.44 10.4 3.0 1.2 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase CENP-B_dimeris PF09026.10 KIY60775.1 - 0.14 12.6 6.3 0.34 11.3 6.3 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF4407 PF14362.6 KIY60777.1 - 0.0094 15.3 0.4 0.015 14.6 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) Dehydrin PF00257.19 KIY60777.1 - 0.019 15.5 1.4 0.033 14.7 1.4 1.4 1 0 0 1 1 1 0 Dehydrin Retrotrans_gag PF03732.17 KIY60777.1 - 0.13 12.5 3.0 0.63 10.3 3.0 2.2 1 1 0 1 1 1 0 Retrotransposon gag protein MFMR_assoc PF16596.5 KIY60777.1 - 0.2 12.1 5.7 0.36 11.3 5.7 1.4 1 0 0 1 1 1 0 Disordered region downstream of MFMR RPOL_N PF14700.6 KIY60777.1 - 0.96 8.8 6.6 1.7 8.0 6.6 1.5 1 1 0 1 1 1 0 DNA-directed RNA polymerase N-terminal TFIIE-A_C PF11521.8 KIY60777.1 - 1.1 9.7 5.4 2.5 8.5 5.4 1.6 1 0 0 1 1 1 0 C-terminal general transcription factor TFIIE alpha DUF3372 PF11852.8 KIY60778.1 - 0.08 12.4 0.4 0.42 10.1 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3372) DUF365 PF04033.12 KIY60778.1 - 0.088 13.1 0.1 0.2 12.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF365) MMR_HSR1 PF01926.23 KIY60779.1 - 8.9e-15 54.8 0.0 1.2e-14 54.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KIY60779.1 - 1.1e-06 28.8 0.0 0.00088 19.4 0.2 2.2 1 1 1 2 2 2 2 Dynamin family AIG1 PF04548.16 KIY60779.1 - 0.00027 20.3 0.0 0.00042 19.7 0.0 1.4 1 1 0 1 1 1 1 AIG1 family FeoB_N PF02421.18 KIY60779.1 - 0.002 17.7 0.0 0.0029 17.2 0.0 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_29 PF13555.6 KIY60779.1 - 0.018 14.8 0.0 0.058 13.1 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KIY60779.1 - 0.031 14.2 0.0 0.089 12.7 0.0 1.7 2 0 0 2 2 2 0 RsgA GTPase AAA_23 PF13476.6 KIY60779.1 - 0.035 14.6 0.0 0.043 14.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 KIY60779.1 - 0.039 13.4 0.0 0.064 12.7 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit F-box-like PF12937.7 KIY60780.1 - 1.6e-10 40.7 1.1 4.3e-10 39.3 1.1 1.8 1 0 0 1 1 1 1 F-box-like Ndc80_HEC PF03801.13 KIY60780.1 - 0.15 11.7 0.3 0.59 9.8 0.0 1.9 2 0 0 2 2 2 0 HEC/Ndc80p family F-box PF00646.33 KIY60780.1 - 0.21 11.5 3.7 4 7.4 3.7 2.8 1 1 0 1 1 1 0 F-box domain DUF4939 PF16297.5 KIY60782.1 - 0.19 11.6 0.0 0.42 10.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) CRA PF06589.11 KIY60783.1 - 0.29 11.2 2.5 0.35 11.0 2.5 1.2 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) gag-asp_proteas PF13975.6 KIY60784.1 - 0.002 18.7 0.0 0.0038 17.8 0.0 1.4 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KIY60784.1 - 0.0025 18.4 0.0 0.0045 17.6 0.0 1.5 2 0 0 2 2 2 1 Aspartyl protease AC_N PF16214.5 KIY60786.1 - 0.19 10.8 1.6 0.78 8.8 1.8 1.7 2 0 0 2 2 2 0 Adenylyl cyclase N-terminal extracellular and transmembrane region DNase_NucA_NucB PF14040.6 KIY60788.1 - 0.046 14.1 0.1 0.065 13.6 0.1 1.2 1 0 0 1 1 1 0 Deoxyribonuclease NucA/NucB TBK1_ULD PF18396.1 KIY60789.1 - 0.013 15.4 0.1 0.034 14.1 0.1 1.7 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Phage_HK97_TLTM PF06120.11 KIY60789.1 - 0.18 11.0 0.0 0.22 10.7 0.0 1.1 1 0 0 1 1 1 0 Tail length tape measure protein Pirin PF02678.16 KIY60791.1 - 2e-28 98.5 2.0 2e-28 98.5 2.0 1.7 2 0 0 2 2 2 1 Pirin Pirin_C_2 PF17954.1 KIY60791.1 - 4.2e-09 36.4 0.0 1.1e-07 32.0 0.0 2.6 2 1 0 2 2 2 1 Quercetinase C-terminal cupin domain Cupin_2 PF07883.11 KIY60791.1 - 5.4e-08 32.4 2.3 6.8e-07 28.9 0.4 2.4 2 0 0 2 2 2 1 Cupin domain Cupin_3 PF05899.12 KIY60791.1 - 0.0015 18.2 1.3 0.11 12.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) Plavaka PF18759.1 KIY60792.1 - 0.035 13.3 0.0 0.04 13.1 0.0 1.1 1 0 0 1 1 1 0 Plavaka transposase PIF1 PF05970.14 KIY60793.1 - 1.7e-12 47.2 0.1 1.8e-12 47.1 0.1 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KIY60793.1 - 1.9e-08 34.3 0.0 2.1e-08 34.1 0.0 1.0 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KIY60793.1 - 2.5e-05 24.6 0.1 4.7e-05 23.8 0.1 1.4 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KIY60793.1 - 0.0055 17.0 0.1 0.0097 16.2 0.1 1.4 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 KIY60793.1 - 0.012 16.0 0.0 0.017 15.5 0.0 1.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.6 KIY60793.1 - 0.039 13.8 0.1 0.13 12.0 0.0 1.7 1 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_5 PF07728.14 KIY60793.1 - 0.046 13.7 0.0 0.064 13.3 0.0 1.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KIY60793.1 - 0.12 11.8 0.0 0.17 11.2 0.0 1.5 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 KIY60793.1 - 0.17 12.2 0.4 0.9 9.9 0.1 1.9 1 1 1 2 2 2 0 AAA ATPase domain IstB_IS21 PF01695.17 KIY60793.1 - 0.27 11.0 1.5 1.4 8.6 0.3 2.1 1 1 1 2 2 2 0 IstB-like ATP binding protein TFIIA PF03153.13 KIY60795.1 - 6.1e-05 23.2 10.2 8e-05 22.8 10.2 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit CAP_N PF01213.19 KIY60795.1 - 0.0019 17.8 10.5 0.0039 16.7 10.5 1.6 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal PPP4R2 PF09184.11 KIY60795.1 - 0.082 12.5 15.2 0.036 13.7 4.0 2.2 2 0 0 2 2 2 0 PPP4R2 PRIMA1 PF16101.5 KIY60795.1 - 1.4 9.0 9.5 2.8 8.0 9.5 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Zn_clus PF00172.18 KIY60795.1 - 4.6 7.5 10.0 8 6.7 1.3 2.3 1 1 1 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Helicase_C PF00271.31 KIY60797.1 - 3.4e-08 33.8 0.0 5.5e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C PF00271.31 KIY60798.1 - 1.3e-09 38.4 0.0 1.5e-08 35.0 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain AAA PF00004.29 KIY60798.1 - 0.087 13.2 0.0 4.6 7.7 0.0 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) GerE PF00196.19 KIY60800.1 - 0.11 12.0 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family KDZ PF18758.1 KIY60804.1 - 1e-49 169.2 0.1 1.3e-49 168.8 0.1 1.1 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KIY60804.1 - 1.8e-18 66.6 1.0 7e-12 45.5 0.0 2.9 2 1 1 3 3 3 2 CxC2 like cysteine cluster associated with KDZ transposases PQQ PF01011.21 KIY60805.1 - 0.33 11.0 3.4 8.2 6.6 0.1 3.6 3 0 0 3 3 3 0 PQQ enzyme repeat DUF3708 PF12501.8 KIY60807.1 - 0.11 12.3 0.1 0.34 10.7 0.1 1.8 2 0 0 2 2 2 0 Phosphate ATP-binding cassette transporter AA_permease PF00324.21 KIY60808.1 - 0.009 14.6 0.0 0.01 14.5 0.0 1.1 1 0 0 1 1 1 1 Amino acid permease ADIP PF11559.8 KIY60813.1 - 0.0085 16.2 3.4 0.68 10.0 0.5 2.3 2 0 0 2 2 2 2 Afadin- and alpha -actinin-Binding Cep57_CLD_2 PF14197.6 KIY60813.1 - 0.021 14.9 2.8 0.021 14.9 2.8 2.7 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 DUF4407 PF14362.6 KIY60813.1 - 0.039 13.3 7.3 0.064 12.6 7.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ATG16 PF08614.11 KIY60813.1 - 0.16 12.2 13.0 0.052 13.8 3.4 2.5 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DivIC PF04977.15 KIY60813.1 - 0.37 10.6 4.6 7.5 6.4 0.4 2.5 2 0 0 2 2 2 0 Septum formation initiator DUF641 PF04859.12 KIY60813.1 - 0.48 10.7 8.6 0.79 10.1 1.6 2.5 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) ACCA PF03255.14 KIY60813.1 - 4.7 7.1 6.0 2.5 7.9 0.4 2.3 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF3545 PF12065.8 KIY60813.1 - 6.5 6.9 10.6 4.2 7.5 3.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3545) Ribonuc_red_sm PF00268.21 KIY60814.1 - 1.5e-122 408.5 1.3 1.8e-122 408.2 1.3 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain DUF4744 PF15918.5 KIY60814.1 - 0.12 13.2 0.0 0.27 12.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4744) Methyltransf_25 PF13649.6 KIY60815.1 - 2.5e-12 47.3 0.0 5.6e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KIY60815.1 - 1.1e-10 41.5 0.1 1.8e-10 40.7 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 KIY60815.1 - 4.1e-10 40.2 0.0 1.2e-09 38.6 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIY60815.1 - 1e-09 38.4 0.0 1.8e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIY60815.1 - 3.5e-06 27.0 0.0 8.1e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 KIY60815.1 - 1.1e-05 25.4 0.0 2.3e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KIY60815.1 - 1.2e-05 24.9 0.0 2e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 KIY60815.1 - 9.5e-05 21.8 0.0 0.00016 21.0 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 KIY60815.1 - 0.0001 23.0 0.0 0.00025 21.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 KIY60815.1 - 0.00012 21.6 0.0 0.00022 20.7 0.0 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_9 PF08003.11 KIY60815.1 - 0.00085 18.3 0.0 0.0014 17.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Met_10 PF02475.16 KIY60815.1 - 0.0016 18.2 0.1 0.006 16.4 0.0 2.0 3 0 0 3 3 3 1 Met-10+ like-protein Methyltransf_16 PF10294.9 KIY60815.1 - 0.013 15.3 0.0 0.022 14.5 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_24 PF13578.6 KIY60815.1 - 0.029 15.4 0.0 0.098 13.7 0.0 1.9 2 0 0 2 2 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 KIY60815.1 - 0.069 12.8 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 PRMT5 PF05185.16 KIY60815.1 - 0.095 12.5 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Plavaka PF18759.1 KIY60816.1 - 6.5e-52 176.8 0.0 7.1e-52 176.6 0.0 1.0 1 0 0 1 1 1 1 Plavaka transposase HGTP_anticodon2 PF12745.7 KIY60818.1 - 0.059 12.9 0.0 0.089 12.3 0.0 1.3 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs KDZ PF18758.1 KIY60819.1 - 3.7e-46 157.5 0.1 5.5e-46 157.0 0.1 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Adeno_PX PF05829.12 KIY60819.1 - 0.017 15.0 0.0 0.036 13.9 0.0 1.4 1 0 0 1 1 1 0 Adenovirus late L2 mu core protein (Protein X) Importin_rep_6 PF18829.1 KIY60819.1 - 0.13 12.4 0.2 0.49 10.6 0.2 1.9 1 0 0 1 1 1 0 Importin repeat 6 KDZ PF18758.1 KIY60826.1 - 1.7e-23 83.4 0.0 2.9e-23 82.7 0.0 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Phage_TAC_4 PF08748.11 KIY60826.1 - 1.9 8.8 4.8 25 5.2 0.1 2.9 2 1 0 3 3 3 0 Phage tail assembly chaperone F-box-like PF12937.7 KIY60828.1 - 0.0022 17.8 1.8 0.0035 17.2 0.5 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIY60828.1 - 0.21 11.5 1.0 0.45 10.5 0.1 2.1 2 0 0 2 2 2 0 F-box domain DUF2028 PF09667.10 KIY60828.1 - 0.42 10.6 4.9 0.68 9.9 4.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2028) RAP1 PF07218.11 KIY60828.1 - 2.1 6.5 8.4 3 6.0 8.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF1285 PF06938.11 KIY60829.1 - 0.034 14.2 0.0 0.047 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1285) Integrase_H2C2 PF17921.1 KIY60833.1 - 3e-06 27.2 0.2 4.7e-06 26.6 0.2 1.3 1 0 0 1 1 1 1 Integrase zinc binding domain Med9 PF07544.13 KIY60834.1 - 0.015 15.4 0.1 0.028 14.5 0.1 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 DUF3747 PF12565.8 KIY60838.1 - 0.086 12.2 0.1 0.12 11.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3747) CLP_protease PF00574.23 KIY60839.1 - 7.8e-07 29.1 0.0 9.8e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 Clp protease CLP_protease PF00574.23 KIY60840.1 - 3.5e-17 62.9 0.3 5.2e-16 59.0 0.3 1.9 1 1 0 1 1 1 1 Clp protease Abhydrolase_4 PF08386.10 KIY60841.1 - 1.8e-24 85.8 0.0 3.1e-24 85.0 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 KIY60841.1 - 3.5e-20 72.8 0.0 3.7e-19 69.4 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIY60841.1 - 0.0064 15.8 0.0 3.7 6.8 0.0 3.1 3 0 0 3 3 3 1 Serine aminopeptidase, S33 zf_UBZ PF18439.1 KIY60845.1 - 0.17 11.5 2.6 1.4 8.6 0.2 2.7 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger SAM_Exu PF18609.1 KIY60845.1 - 2.1 8.5 5.8 3.7 7.7 0.2 3.3 3 0 0 3 3 3 0 Exuperantia SAM-like domain Phenol_monoox PF04663.12 KIY60846.1 - 0.059 13.5 0.1 0.11 12.6 0.1 1.5 1 0 0 1 1 1 0 Phenol hydroxylase conserved region Plavaka PF18759.1 KIY60847.1 - 3.2e-111 371.6 0.2 3.6e-111 371.5 0.2 1.0 1 0 0 1 1 1 1 Plavaka transposase NAD_binding_10 PF13460.6 KIY60850.1 - 8.9e-06 25.7 0.0 1.3e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding FAD_binding_3 PF01494.19 KIY60851.1 - 7.4e-12 45.2 0.0 7.8e-12 45.1 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KIY60851.1 - 0.082 12.1 0.1 0.095 11.9 0.1 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KIY60851.1 - 0.1 11.8 0.0 0.1 11.8 0.0 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KIY60851.1 - 0.1 11.3 0.1 0.11 11.1 0.1 1.0 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_2 PF00890.24 KIY60851.1 - 0.17 10.9 0.1 0.18 10.8 0.1 1.0 1 0 0 1 1 1 0 FAD binding domain VraX PF17412.2 KIY60851.1 - 0.17 11.5 0.1 1.9 8.2 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function KDZ PF18758.1 KIY60852.1 - 6.6e-45 153.4 0.7 1e-44 152.8 0.4 1.5 2 0 0 2 2 2 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KIY60852.1 - 4.7e-29 100.7 0.1 4.7e-29 100.7 0.1 1.9 2 0 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases SMC_N PF02463.19 KIY60852.1 - 0.048 13.1 0.0 0.083 12.3 0.0 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Plavaka PF18759.1 KIY60853.1 - 4.8e-27 95.0 0.1 5.1e-27 94.9 0.1 1.0 1 0 0 1 1 1 1 Plavaka transposase Plavaka PF18759.1 KIY60854.1 - 1.2e-12 47.7 0.0 1.8e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Plavaka transposase Plavaka PF18759.1 KIY60855.1 - 1.8e-14 53.7 0.3 2.9e-14 53.0 0.3 1.4 1 0 0 1 1 1 1 Plavaka transposase cIII PF08134.11 KIY60855.1 - 0.12 12.1 1.0 0.24 11.2 1.0 1.5 1 0 0 1 1 1 0 cIII protein family Transposase_21 PF02992.14 KIY60858.1 - 9.7e-07 28.2 0.0 1.6e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 DDT PF02791.17 KIY60858.1 - 0.0057 16.9 0.1 0.019 15.3 0.1 1.8 1 0 0 1 1 1 1 DDT domain DUF4218 PF13960.6 KIY60858.1 - 0.023 14.3 0.1 0.04 13.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) Plavaka PF18759.1 KIY60858.1 - 0.043 13.0 0.1 0.069 12.4 0.1 1.2 1 0 0 1 1 1 0 Plavaka transposase Pkinase_fungal PF17667.1 KIY60859.1 - 0.092 11.5 0.0 0.89 8.3 0.0 2.2 3 0 0 3 3 3 0 Fungal protein kinase Asp PF00026.23 KIY60860.1 - 1.5e-71 241.4 5.8 1.8e-71 241.2 5.8 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIY60860.1 - 3.2e-11 43.8 1.1 1.4e-06 28.7 0.1 2.4 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 KIY60860.1 - 0.066 13.0 0.0 0.32 10.8 0.0 2.0 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal RNA_pol_Rpa2_4 PF06883.12 KIY60862.1 - 0.078 13.0 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase I, Rpa2 specific domain Hamartin PF04388.12 KIY60862.1 - 6.7 5.2 6.3 9 4.8 6.3 1.1 1 0 0 1 1 1 0 Hamartin protein PI3_PI4_kinase PF00454.27 KIY60864.1 - 1.2e-08 35.0 0.0 1.2e-08 35.0 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DBD_Tnp_Hermes PF10683.9 KIY60865.1 - 0.0026 17.4 0.2 0.051 13.3 0.0 2.3 2 0 0 2 2 2 1 Hermes transposase DNA-binding domain Dimer_Tnp_hAT PF05699.14 KIY60868.1 - 3.4e-19 68.4 0.2 4.9e-19 67.9 0.2 1.2 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.6 KIY60869.1 - 0.026 14.9 0.2 0.042 14.2 0.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4413) RVP_2 PF08284.11 KIY60872.1 - 1.3e-07 31.5 0.0 1.4e-07 31.4 0.0 1.0 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 KIY60872.1 - 2.9e-06 27.8 0.0 3.6e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KIY60872.1 - 7.6e-05 23.3 0.0 0.0001 22.9 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease DUF1758 PF05585.12 KIY60872.1 - 0.06 13.1 0.0 0.094 12.5 0.0 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF1758) CAF1C_H4-bd PF12265.8 KIY60873.1 - 0.15 12.3 0.0 0.35 11.2 0.0 1.6 1 0 0 1 1 1 0 Histone-binding protein RBBP4 or subunit C of CAF1 complex IFRD PF05004.13 KIY60875.1 - 0.035 13.2 0.8 0.26 10.4 0.3 2.1 1 1 1 2 2 2 0 Interferon-related developmental regulator (IFRD) RdDM_RDM1 PF09187.10 KIY60875.1 - 0.065 13.3 0.1 0.1 12.6 0.1 1.3 1 0 0 1 1 1 0 RNA-directed DNA methylation 1 PgaPase_1 PF06162.12 KIY60875.1 - 0.068 12.9 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Putative pyroglutamyl peptidase PgaPase_1 HEPN_SAV2148 PF18725.1 KIY60875.1 - 0.069 12.6 1.0 0.32 10.4 0.1 2.0 1 1 1 2 2 2 0 SAV2148-like HEPN Coleoptericin PF06286.11 KIY60877.1 - 0.091 12.9 0.6 0.17 12.0 0.6 1.4 1 0 0 1 1 1 0 Coleoptericin DBP10CT PF08147.12 KIY60878.1 - 0.0068 16.6 0.0 3.8 7.8 0.0 2.4 2 0 0 2 2 2 2 DBP10CT (NUC160) domain CxC2 PF18803.1 KIY60882.1 - 5.9e-25 87.5 0.0 1.2e-24 86.6 0.0 1.5 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases KDZ PF18758.1 KIY60882.1 - 9.7e-21 74.4 0.0 1.4e-20 73.9 0.0 1.2 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 KIY60882.1 - 8.1e-07 29.2 0.0 1.5e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 KIY60882.1 - 0.0021 17.9 0.0 0.0055 16.5 0.0 1.7 1 0 0 1 1 1 1 CxC3 like cysteine cluster associated with KDZ transposases CxC4 PF18717.1 KIY60882.1 - 0.0071 16.2 0.0 0.044 13.6 0.0 2.3 1 1 0 1 1 1 1 CxC4 like cysteine cluster associated with KDZ transposases ZZ PF00569.17 KIY60882.1 - 0.12 12.2 8.5 0.33 10.8 8.5 1.8 1 0 0 1 1 1 0 Zinc finger, ZZ type F-box-like PF12937.7 KIY60883.1 - 1e-10 41.3 0.5 3.2e-10 39.7 0.5 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY60883.1 - 0.039 13.8 0.1 0.15 12.0 0.1 2.0 1 0 0 1 1 1 0 F-box domain Fungal_trans PF04082.18 KIY60883.1 - 0.061 12.3 0.0 0.09 11.8 0.0 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain Myb_DNA-bind_5 PF13873.6 KIY60884.1 - 0.011 15.8 0.3 0.44 10.7 0.3 2.3 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain DUF5082 PF16888.5 KIY60884.1 - 0.019 15.3 0.1 0.028 14.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) Uso1_p115_C PF04871.13 KIY60884.1 - 0.038 14.4 0.5 0.061 13.7 0.5 1.2 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Myb_DNA-bind_4 PF13837.6 KIY60884.1 - 0.057 13.8 1.6 0.26 11.7 1.6 2.0 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 KIY60884.1 - 0.11 12.8 0.3 0.4 11.0 0.1 1.9 1 1 1 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DDE_Tnp_4 PF13359.6 KIY60885.1 - 5.2e-10 39.2 0.2 6.6e-10 38.9 0.2 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_4 PF13359.6 KIY60886.1 - 0.0082 15.8 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Pam17 PF08566.10 KIY60887.1 - 0.0084 16.0 0.1 4.5 7.1 0.0 2.3 2 0 0 2 2 2 2 Mitochondrial import protein Pam17 zf-CCHC PF00098.23 KIY60887.1 - 0.011 15.8 2.1 0.019 15.0 2.1 1.4 1 0 0 1 1 1 0 Zinc knuckle DUF3664 PF12406.8 KIY60887.1 - 0.23 12.1 1.7 2.5 8.8 0.2 2.4 2 0 0 2 2 2 0 Surface protein LEA_6 PF10714.9 KIY60887.1 - 1 9.5 4.6 22 5.2 0.2 2.9 2 1 0 2 2 2 0 Late embryogenesis abundant protein 18 HNH_2 PF13391.6 KIY60889.1 - 8.7e-06 25.8 0.0 1.5e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 HNH endonuclease PHD_2 PF13831.6 KIY60889.1 - 0.17 11.5 1.0 0.26 10.9 0.1 1.7 2 0 0 2 2 2 0 PHD-finger Glyco_hydro_43 PF04616.14 KIY60890.1 - 7.4e-31 107.5 0.1 8.5e-31 107.3 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Ank_4 PF13637.6 KIY60891.1 - 0.099 13.3 0.0 0.27 11.9 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (many copies) CPSase_L_D2 PF02786.17 KIY60892.1 - 2.7e-11 43.4 0.0 4e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Dala_Dala_lig_C PF07478.13 KIY60892.1 - 2.1e-05 24.2 0.0 3.6e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KIY60892.1 - 0.0011 18.5 0.0 0.0019 17.8 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D3 PF02787.19 KIY60892.1 - 0.0022 18.3 0.2 0.026 14.9 0.2 2.4 1 1 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain MGS PF02142.22 KIY60892.1 - 0.028 14.6 0.0 0.094 12.9 0.0 1.9 2 0 0 2 2 2 0 MGS-like domain TBK1_ULD PF18396.1 KIY60895.1 - 0.17 11.9 0.0 0.32 11.0 0.0 1.4 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain DUF2170 PF09938.9 KIY60896.1 - 0.066 12.9 0.0 0.088 12.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2170) PUF PF00806.19 KIY60896.1 - 0.17 11.7 0.0 0.39 10.5 0.0 1.6 1 0 0 1 1 1 0 Pumilio-family RNA binding repeat DUF2380 PF09533.10 KIY60897.1 - 0.18 11.4 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 Predicted lipoprotein of unknown function (DUF2380) JmjC PF02373.22 KIY60898.1 - 3.2e-13 50.1 1.4 7.8e-13 48.9 0.0 2.2 3 0 0 3 3 3 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 KIY60898.1 - 0.055 13.2 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 Cupin domain zf-CCCH PF00642.24 KIY60902.1 - 0.018 14.9 1.1 0.041 13.8 1.1 1.6 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KIY60902.1 - 0.099 12.7 1.2 0.19 11.8 1.2 1.5 1 0 0 1 1 1 0 Zinc finger domain Seryl_tRNA_N PF02403.22 KIY60902.1 - 0.35 11.1 3.1 0.72 10.1 3.1 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF4407 PF14362.6 KIY60902.1 - 0.54 9.5 7.3 0.99 8.7 7.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Peptidase_M24 PF00557.24 KIY60903.1 - 2.8e-15 56.6 0.0 4.1e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 RNA_POL_M_15KD PF02150.16 KIY60903.1 - 0.088 12.7 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 RNA polymerases M/15 Kd subunit Integrase_H2C2 PF17921.1 KIY60905.1 - 4.1e-06 26.8 0.4 5.9e-06 26.3 0.4 1.3 1 0 0 1 1 1 1 Integrase zinc binding domain RVP_2 PF08284.11 KIY60906.1 - 4.9e-07 29.6 0.0 7e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 KIY60906.1 - 3.4e-05 24.3 0.0 6.6e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KIY60906.1 - 0.00013 22.5 0.0 0.00024 21.7 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease DUF1758 PF05585.12 KIY60906.1 - 0.14 11.9 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 Putative peptidase (DUF1758) CxC2 PF18803.1 KIY60907.1 - 3.5e-30 104.3 0.0 4.8e-30 103.9 0.0 1.2 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KIY60907.1 - 0.00082 19.5 0.1 0.0014 18.8 0.1 1.4 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 KIY60907.1 - 0.0033 17.2 2.4 0.005 16.7 0.0 2.0 2 0 0 2 2 2 1 CxC3 like cysteine cluster associated with KDZ transposases KDZ PF18758.1 KIY60910.1 - 3.3e-30 105.4 0.1 5.3e-30 104.7 0.1 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase RVT_N PF13655.6 KIY60910.1 - 0.16 12.2 0.2 34 4.8 0.0 3.5 3 0 0 3 3 3 0 N-terminal domain of reverse transcriptase CALCOCO1 PF07888.11 KIY60912.1 - 0.00097 18.1 10.9 0.0014 17.6 10.9 1.1 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like Cluap1 PF10234.9 KIY60912.1 - 0.01 15.3 1.0 0.01 15.3 1.0 2.1 1 1 1 2 2 2 0 Clusterin-associated protein-1 SlyX PF04102.12 KIY60912.1 - 0.059 14.0 8.2 0.27 11.9 1.4 3.2 2 1 0 2 2 2 0 SlyX EMP24_GP25L PF01105.24 KIY60912.1 - 0.073 13.0 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Seryl_tRNA_N PF02403.22 KIY60912.1 - 0.096 12.9 10.3 0.059 13.6 2.8 2.5 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain LemA PF04011.12 KIY60912.1 - 0.15 11.9 2.8 0.43 10.4 2.8 1.8 1 1 0 1 1 1 0 LemA family Prefoldin_2 PF01920.20 KIY60912.1 - 0.19 11.7 6.8 1.6 8.7 0.4 3.3 2 1 0 2 2 2 0 Prefoldin subunit DUF16 PF01519.16 KIY60912.1 - 0.22 12.0 4.0 2.5 8.7 0.4 2.3 1 1 1 2 2 2 0 Protein of unknown function DUF16 Fib_alpha PF08702.10 KIY60912.1 - 0.29 11.3 5.0 0.58 10.3 0.6 2.6 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family BLOC1_2 PF10046.9 KIY60912.1 - 0.31 11.4 3.6 22 5.4 0.2 3.3 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 GIT_CC PF16559.5 KIY60912.1 - 0.31 10.9 4.3 34 4.4 0.1 3.8 3 1 1 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor Syntaxin-6_N PF09177.11 KIY60912.1 - 0.39 11.3 4.9 0.9 10.1 0.3 2.8 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Tropomyosin PF00261.20 KIY60912.1 - 0.51 9.7 14.9 0.51 9.7 13.7 1.5 1 1 0 1 1 1 0 Tropomyosin Tropomyosin_1 PF12718.7 KIY60912.1 - 0.52 10.4 13.1 0.27 11.4 8.4 2.5 1 1 2 3 3 3 0 Tropomyosin like TetR_C_11 PF16859.5 KIY60912.1 - 0.6 10.4 4.0 0.79 10.1 0.9 2.7 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain ZapB PF06005.12 KIY60912.1 - 1.5 9.3 11.6 0.56 10.7 2.3 2.8 3 0 0 3 3 2 0 Cell division protein ZapB Spc24 PF08286.11 KIY60912.1 - 2.3 8.5 10.3 0.15 12.3 1.9 2.8 1 1 1 3 3 3 0 Spc24 subunit of Ndc80 KELK PF15796.5 KIY60912.1 - 2.9 8.4 7.4 1.2 9.6 3.3 2.5 1 1 1 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase CRISPR_Cse2 PF09485.10 KIY60912.1 - 3.1 8.3 8.5 7.9 7.0 8.5 1.8 1 1 0 1 1 1 0 CRISPR-associated protein Cse2 (CRISPR_cse2) Spc7 PF08317.11 KIY60912.1 - 4 6.2 15.3 1.3 7.9 4.4 2.5 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF4164 PF13747.6 KIY60912.1 - 6.3 7.1 17.2 4.6 7.6 7.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) CENP-F_leu_zip PF10473.9 KIY60912.1 - 8 6.5 12.9 17 5.5 10.0 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Glyco_hydro_18 PF00704.28 KIY60913.1 - 1.9e-26 93.6 0.1 7.5e-24 85.0 0.1 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Cauli_VI PF01693.16 KIY60917.1 - 6.6e-06 26.3 0.0 0.049 13.9 0.0 2.6 2 0 0 2 2 2 2 Caulimovirus viroplasmin F-box-like PF12937.7 KIY60919.1 - 3.3e-09 36.5 2.7 6.9e-09 35.5 2.7 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY60919.1 - 0.033 14.1 2.3 19 5.3 0.0 3.8 4 0 0 4 4 4 0 F-box domain LpxI_N PF17930.1 KIY60919.1 - 0.12 12.2 0.0 0.4 10.6 0.0 1.9 2 0 0 2 2 2 0 LpxI N-terminal domain DUF1188 PF06690.11 KIY60919.1 - 0.13 11.7 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) TOH_N PF12549.8 KIY60920.1 - 0.051 13.4 0.1 0.15 12.0 0.1 1.8 1 0 0 1 1 1 0 Tyrosine hydroxylase N terminal Fungal_trans PF04082.18 KIY60921.1 - 9.9e-17 60.8 0.0 1.9e-16 59.9 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY60921.1 - 4.5e-07 29.9 13.9 8.1e-07 29.1 13.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dynamitin PF04912.14 KIY60921.1 - 0.018 14.4 0.1 0.027 13.8 0.1 1.1 1 0 0 1 1 1 0 Dynamitin EpmC PF04315.12 KIY60921.1 - 0.076 12.7 0.1 0.3 10.8 0.0 1.9 1 1 1 2 2 2 0 Elongation factor P hydroxylase DUF3446 PF11928.8 KIY60921.1 - 0.21 11.9 3.3 2.6 8.4 0.2 2.8 2 0 0 2 2 2 0 Early growth response N-terminal domain DASH_Ask1 PF08655.10 KIY60923.1 - 0.082 12.8 0.2 0.29 11.0 0.0 1.9 2 0 0 2 2 2 0 DASH complex subunit Ask1 Retrotrans_gag PF03732.17 KIY60925.1 - 3.6e-11 43.2 0.0 7.3e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein DUF4939 PF16297.5 KIY60925.1 - 0.019 14.8 0.0 0.042 13.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) DUF4413 PF14372.6 KIY60926.1 - 0.002 18.5 0.4 0.0043 17.4 0.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4413) Afaf PF15339.6 KIY60927.1 - 0.00047 19.9 0.0 0.0016 18.2 0.0 1.8 1 1 1 2 2 2 1 Acrosome formation-associated factor Retrotrans_gag PF03732.17 KIY60928.1 - 8.5e-11 42.0 0.1 1.4e-10 41.3 0.1 1.3 1 0 0 1 1 1 1 Retrotransposon gag protein DUF4939 PF16297.5 KIY60928.1 - 0.021 14.7 0.0 0.031 14.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) ATP-grasp_6 PF18419.1 KIY60930.1 - 0.41 10.3 5.4 7.8 6.2 0.2 3.6 4 0 0 4 4 4 0 ATP-grasp-like domain DUF659 PF04937.15 KIY60931.1 - 2.2e-05 24.4 0.0 4.1e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) TipE PF16972.5 KIY60932.1 - 0.025 13.8 0.6 0.026 13.7 0.6 1.0 1 0 0 1 1 1 0 Na+ channel auxiliary subunit TipE Phage_integrase PF00589.22 KIY60933.1 - 3.4e-05 23.7 0.0 0.00011 22.0 0.0 1.9 2 0 0 2 2 2 1 Phage integrase family Sec7 PF01369.20 KIY60935.1 - 0.16 11.7 0.0 0.18 11.4 0.0 1.1 1 0 0 1 1 1 0 Sec7 domain DDE_3 PF13358.6 KIY60939.1 - 0.12 12.1 0.1 0.35 10.6 0.0 1.8 2 1 0 2 2 2 0 DDE superfamily endonuclease DDE_3 PF13358.6 KIY60940.1 - 1.7e-05 24.7 0.0 0.0021 17.8 0.0 2.4 2 0 0 2 2 2 2 DDE superfamily endonuclease KDZ PF18758.1 KIY60941.1 - 4.4e-40 137.7 0.0 7.5e-40 136.9 0.0 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase PerC PF06069.11 KIY60941.1 - 0.13 12.5 1.7 0.56 10.5 1.7 2.1 1 0 0 1 1 1 0 PerC transcriptional activator Plavaka PF18759.1 KIY60945.1 - 1.2e-15 57.6 0.0 1.5e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase Pyr_redox_2 PF07992.14 KIY60948.1 - 3.8e-12 46.0 0.2 5.2e-07 29.2 0.1 2.0 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIY60948.1 - 0.002 18.7 0.0 0.0032 18.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase KDZ PF18758.1 KIY60949.1 - 1e-41 143.0 0.0 2.3e-41 141.8 0.0 1.6 2 0 0 2 2 2 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KIY60949.1 - 1.7e-24 86.0 0.0 3.7e-24 84.9 0.0 1.6 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KIY60949.1 - 2e-05 24.7 0.2 7e-05 22.9 0.2 1.9 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 KIY60949.1 - 0.012 15.5 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 CxC3 like cysteine cluster associated with KDZ transposases HetR_C PF18460.1 KIY60949.1 - 0.86 9.6 4.9 31 4.6 3.2 2.9 2 0 0 2 2 2 0 Heterocyst differentiation regulator C-terminal Hood domain Rootletin PF15035.6 KIY60949.1 - 4 7.4 12.1 11 6.0 6.7 2.7 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion KDZ PF18758.1 KIY60951.1 - 1.4e-51 175.3 1.2 5e-51 173.5 1.1 1.9 2 0 0 2 2 2 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KIY60951.1 - 8.4e-31 106.3 0.1 6.4e-30 103.5 0.0 2.3 2 0 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KIY60951.1 - 5.5e-06 26.5 0.0 2.6e-05 24.3 0.0 2.0 2 0 0 2 2 2 1 CxC1 like cysteine cluster associated with KDZ transposases zf-UBR PF02207.20 KIY60951.1 - 0.0016 18.6 4.7 0.0016 18.6 4.7 2.1 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) zf-B_box PF00643.24 KIY60951.1 - 0.017 15.3 3.5 0.052 13.7 3.5 1.9 1 0 0 1 1 1 0 B-box zinc finger Sugar_tr PF00083.24 KIY60952.1 - 0.0002 20.3 0.1 0.0002 20.3 0.1 1.4 2 0 0 2 2 2 1 Sugar (and other) transporter F-box-like PF12937.7 KIY60953.1 - 1.8e-06 27.7 0.3 3.3e-06 26.9 0.3 1.4 1 1 0 1 1 1 1 F-box-like ADIP PF11559.8 KIY60953.1 - 0.005 16.9 0.1 0.0063 16.6 0.1 1.1 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding F-box PF00646.33 KIY60953.1 - 0.0085 16.0 1.5 2.9 7.9 0.2 2.3 2 0 0 2 2 2 2 F-box domain TMF_TATA_bd PF12325.8 KIY60953.1 - 0.028 14.6 0.1 0.037 14.3 0.1 1.1 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding ABC_tran_CTD PF16326.5 KIY60953.1 - 0.033 14.4 0.2 0.046 14.0 0.2 1.2 1 0 0 1 1 1 0 ABC transporter C-terminal domain DUF3450 PF11932.8 KIY60953.1 - 0.056 12.7 0.1 0.065 12.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Paralemmin PF03285.15 KIY60953.1 - 0.06 12.9 0.1 0.06 12.9 0.1 1.0 1 0 0 1 1 1 0 Paralemmin BLOC1_2 PF10046.9 KIY60953.1 - 0.072 13.4 0.1 0.096 13.0 0.1 1.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 WD40_alt PF14077.6 KIY60953.1 - 0.11 12.4 0.2 0.18 11.7 0.2 1.3 1 0 0 1 1 1 0 Alternative WD40 repeat motif MAD PF05557.13 KIY60953.1 - 0.16 10.3 0.3 0.19 10.1 0.3 1.0 1 0 0 1 1 1 0 Mitotic checkpoint protein TPD52 PF04201.15 KIY60953.1 - 0.29 10.7 2.2 0.16 11.5 0.5 1.4 2 0 0 2 2 2 0 Tumour protein D52 family F-box-like PF12937.7 KIY60955.1 - 2.1e-07 30.7 1.2 2.1e-07 30.7 1.2 2.8 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 KIY60955.1 - 0.012 15.5 0.4 0.04 13.8 0.2 2.1 2 0 0 2 2 2 0 F-box domain Cep57_CLD_2 PF14197.6 KIY60955.1 - 0.13 12.4 0.3 0.25 11.5 0.3 1.5 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 KRAB PF01352.27 KIY60957.1 - 0.012 15.2 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 KRAB box zf-UBR PF02207.20 KIY60959.1 - 0.0028 17.8 0.5 0.0086 16.2 0.5 1.8 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) CxC2 PF18803.1 KIY60959.1 - 0.026 14.7 0.1 0.026 14.7 0.1 1.6 2 0 0 2 2 2 0 CxC2 like cysteine cluster associated with KDZ transposases HTH_32 PF13565.6 KIY60962.1 - 0.081 13.6 0.0 0.14 12.8 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain DDE_Tnp_4 PF13359.6 KIY60963.1 - 1.3e-18 67.1 0.0 2e-18 66.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease WHH PF14414.6 KIY60963.1 - 0.013 15.4 0.2 0.64 9.9 0.0 2.4 2 0 0 2 2 2 0 A nuclease of the HNH/ENDO VII superfamily with conserved WHH PRIMA1 PF16101.5 KIY60966.1 - 0.028 14.4 8.4 0.045 13.8 8.4 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 KIY60966.1 - 0.029 13.9 6.2 0.044 13.3 6.2 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 KIY60966.1 - 0.04 14.0 6.0 0.058 13.5 6.0 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator Cauli_VI PF01693.16 KIY60967.1 - 1.8e-05 25.0 0.1 5.5e-05 23.4 0.1 1.8 1 0 0 1 1 1 1 Caulimovirus viroplasmin Mucin-like PF16058.5 KIY60967.1 - 3.4 7.8 8.7 0.41 10.7 2.8 2.3 3 0 0 3 3 3 0 Mucin-like Mobilization_B PF17511.2 KIY60968.1 - 0.068 13.5 0.2 0.088 13.2 0.2 1.3 1 1 0 1 1 1 0 Mobilization protein B FixS PF03597.15 KIY60969.1 - 0.0024 17.5 0.0 0.0047 16.6 0.0 1.4 1 0 0 1 1 1 1 Cytochrome oxidase maturation protein cbb3-type F-box-like PF12937.7 KIY60971.1 - 3.8e-08 33.1 0.3 7.4e-08 32.2 0.3 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY60971.1 - 0.016 15.1 1.0 0.016 15.1 1.0 2.2 2 1 0 2 2 2 0 F-box domain GalKase_gal_bdg PF10509.9 KIY60972.1 - 5.8e-09 35.4 0.0 1.4e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 KIY60972.1 - 3.9e-07 30.2 0.3 8.6e-07 29.1 0.3 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain adh_short_C2 PF13561.6 KIY60973.1 - 2e-57 194.4 0.1 2.6e-57 194.1 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIY60973.1 - 2.6e-44 151.0 0.4 4.1e-44 150.4 0.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIY60973.1 - 9e-09 35.5 0.1 2e-08 34.4 0.1 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KIY60973.1 - 0.02 14.3 0.1 0.072 12.5 0.1 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family ThiF PF00899.21 KIY60973.1 - 0.06 12.7 0.0 0.16 11.3 0.0 1.7 2 0 0 2 2 2 0 ThiF family Polysacc_synt_2 PF02719.15 KIY60973.1 - 0.13 11.4 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DLH PF01738.18 KIY60974.1 - 2e-23 83.1 0.0 2.2e-23 82.9 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Neuralized PF07177.12 KIY60976.1 - 0.11 12.5 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Neuralized MerR-DNA-bind PF09278.11 KIY60976.1 - 0.17 12.5 4.5 0.65 10.6 0.5 2.9 3 0 0 3 3 3 0 MerR, DNA binding DUF5372 PF17342.2 KIY60979.1 - 0.035 14.5 0.1 0.092 13.2 0.0 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5372) KDZ PF18758.1 KIY60981.1 - 1.4e-48 165.5 0.0 1.8e-48 165.1 0.0 1.1 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KIY60981.1 - 6.3e-34 116.4 0.1 1e-33 115.7 0.1 1.3 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KIY60981.1 - 0.00018 21.6 0.0 0.00039 20.5 0.0 1.6 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases Cauli_VI PF01693.16 KIY60982.1 - 2.3e-06 27.8 0.1 4.2e-06 27.0 0.1 1.4 1 0 0 1 1 1 1 Caulimovirus viroplasmin MAGI_u1 PF16663.5 KIY60984.1 - 0.019 15.0 0.0 0.035 14.2 0.0 1.4 1 0 0 1 1 1 0 Unstructured region on MAGI CENP-T_C PF15511.6 KIY60985.1 - 4.9e-07 29.9 0.0 5.9e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 KIY60985.1 - 3.4e-05 23.9 0.1 4.8e-05 23.5 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 KIY60985.1 - 0.0002 21.6 0.0 0.00026 21.3 0.0 1.3 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KIY60985.1 - 0.00085 19.6 0.1 0.0016 18.7 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KIY60985.1 - 0.00094 19.5 0.2 0.0011 19.4 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KIY60985.1 - 0.058 13.5 0.0 0.067 13.3 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KIY60985.1 - 0.14 12.2 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated PTS_2-RNA PF01885.16 KIY60986.1 - 4.8e-11 43.0 0.0 8.2e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family HMG_box PF00505.19 KIY60987.1 - 0.0062 16.9 0.5 0.068 13.6 0.5 2.2 1 1 0 1 1 1 1 HMG (high mobility group) box PHINT_rpt PF14882.6 KIY60988.1 - 0.039 14.2 0.8 0.082 13.2 0.8 1.5 1 0 0 1 1 1 0 Phage-integrase repeat unit DUF2722 PF10846.8 KIY60990.1 - 0.041 12.8 0.2 0.052 12.5 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DDE_3 PF13358.6 KIY60991.1 - 2.9e-08 33.6 0.1 3.2e-08 33.4 0.1 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease YAcAr PF10686.9 KIY60991.1 - 0.075 13.0 0.0 0.099 12.6 0.0 1.1 1 0 0 1 1 1 0 YspA, cpYpsA-related SLOG family rve PF00665.26 KIY60991.1 - 0.12 12.6 0.0 0.12 12.6 0.0 1.0 1 0 0 1 1 1 0 Integrase core domain KDZ PF18758.1 KIY60993.1 - 3.8e-52 177.1 0.2 6e-52 176.5 0.2 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KIY60993.1 - 3.5e-29 101.1 0.0 6.8e-29 100.2 0.0 1.5 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KIY60993.1 - 9e-05 22.6 0.0 0.00022 21.3 0.0 1.6 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases DUF659 PF04937.15 KIY61000.1 - 0.0011 18.8 0.0 0.0038 17.1 0.0 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF 659) gag_pre-integrs PF13976.6 KIY61002.1 - 7.9e-11 41.7 0.0 1e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 GAG-pre-integrase domain zf-CCHC_3 PF13917.6 KIY61003.1 - 0.13 12.2 3.6 0.27 11.2 3.6 1.5 1 0 0 1 1 1 0 Zinc knuckle DHO_dh PF01180.21 KIY61004.1 - 0.031 13.5 0.0 0.04 13.1 0.0 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase Plavaka PF18759.1 KIY61005.1 - 4.6e-13 49.1 1.8 8.8e-13 48.2 1.8 1.5 2 0 0 2 2 2 1 Plavaka transposase Plavaka PF18759.1 KIY61006.1 - 2.5e-62 211.0 0.0 2.8e-62 210.8 0.0 1.0 1 0 0 1 1 1 1 Plavaka transposase Plavaka PF18759.1 KIY61007.1 - 1.6e-18 67.0 0.1 2.2e-18 66.6 0.1 1.2 1 0 0 1 1 1 1 Plavaka transposase DUF1488 PF07369.11 KIY61009.1 - 0.1 12.6 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1488) Gas_vesicle_C PF01304.17 KIY61010.1 - 0.097 12.7 0.9 0.19 11.8 0.9 1.5 1 0 0 1 1 1 0 Gas vesicles protein GVPc repeated domain PIF1 PF05970.14 KIY61017.1 - 1.1e-06 28.1 0.0 1.5e-05 24.4 0.0 2.2 2 0 0 2 2 2 2 PIF1-like helicase PIF1 PF05970.14 KIY61018.1 - 1.6e-13 50.6 0.0 1.8e-13 50.4 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KIY61018.1 - 1.3e-08 34.8 0.0 1.5e-08 34.6 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KIY61018.1 - 3.7e-07 30.6 0.0 6.5e-07 29.8 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KIY61018.1 - 0.00012 22.6 0.0 0.00013 22.4 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KIY61018.1 - 0.0084 16.4 0.0 0.012 15.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_PrkA PF08298.11 KIY61018.1 - 0.025 13.5 0.0 0.031 13.2 0.0 1.1 1 0 0 1 1 1 0 PrkA AAA domain AAA_5 PF07728.14 KIY61018.1 - 0.032 14.2 0.0 0.094 12.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Guanylate_kin PF00625.21 KIY61018.1 - 0.048 13.4 0.0 1.4 8.5 0.0 2.1 1 1 1 2 2 2 0 Guanylate kinase Helicase_RecD PF05127.14 KIY61018.1 - 0.13 12.1 0.0 0.18 11.6 0.0 1.1 1 0 0 1 1 1 0 Helicase AAA_11 PF13086.6 KIY61018.1 - 0.17 11.6 0.0 0.72 9.6 0.0 1.7 1 1 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 KIY61018.1 - 0.18 10.7 0.0 0.24 10.3 0.0 1.3 1 1 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain COesterase PF00135.28 KIY61021.1 - 2e-79 267.9 0.0 1.5e-77 261.7 0.0 2.0 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 KIY61021.1 - 0.098 12.1 0.1 0.15 11.5 0.1 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 KIY61021.1 - 0.16 11.8 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Pkinase_fungal PF17667.1 KIY61023.1 - 8.9e-16 57.7 0.0 4.7e-14 52.0 0.0 2.6 2 1 0 2 2 2 2 Fungal protein kinase CNDH2_C PF16858.5 KIY61025.1 - 0.011 15.7 4.6 0.013 15.4 4.6 1.2 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term CDC27 PF09507.10 KIY61025.1 - 0.015 14.7 14.5 0.02 14.3 14.5 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF1178 PF06676.11 KIY61025.1 - 3.1 8.2 7.1 0.68 10.3 3.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1178) Rep_1B PF17873.1 KIY61026.1 - 0.078 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Replicase polyprotein 1ab zf-UBR PF02207.20 KIY61026.1 - 0.26 11.5 6.6 0.11 12.7 4.0 1.7 1 1 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) DUF3086 PF11285.8 KIY61027.1 - 0.071 12.2 0.0 0.088 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) Apt1 PF10351.9 KIY61028.1 - 4.4 6.1 7.0 4.6 6.0 7.0 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain ABC_tran PF00005.27 KIY61030.1 - 0.0003 21.3 0.0 0.00093 19.7 0.0 1.8 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 KIY61030.1 - 0.00045 20.2 0.0 0.00091 19.2 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase IIGP PF05049.13 KIY61030.1 - 0.0021 17.2 0.0 0.0034 16.5 0.0 1.2 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) AAA_29 PF13555.6 KIY61030.1 - 0.0027 17.4 0.0 0.0064 16.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KIY61030.1 - 0.0055 16.8 0.0 0.012 15.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_23 PF13476.6 KIY61030.1 - 0.0074 16.8 0.0 0.013 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KIY61030.1 - 0.0092 16.4 0.0 0.02 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain DUF87 PF01935.17 KIY61030.1 - 0.022 14.9 0.0 0.058 13.5 0.0 1.7 1 0 0 1 1 1 0 Helicase HerA, central domain Dynamin_N PF00350.23 KIY61030.1 - 0.056 13.5 0.2 0.3 11.1 0.0 2.1 2 0 0 2 2 2 0 Dynamin family SMC_N PF02463.19 KIY61030.1 - 0.12 11.8 0.1 0.25 10.8 0.1 1.5 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain TniB PF05621.11 KIY61030.1 - 0.15 11.5 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein zf-C2H2_4 PF13894.6 KIY61030.1 - 0.26 12.2 1.3 3.9 8.6 0.1 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger Exo_endo_phos PF03372.23 KIY61031.1 - 5.1e-07 29.4 0.0 8.4e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 KIY61031.1 - 0.0016 18.3 0.0 0.0094 15.8 0.0 2.3 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase RVT_1 PF00078.27 KIY61032.1 - 3.6e-07 29.9 0.0 5.5e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Cauli_VI PF01693.16 KIY61034.1 - 2.8e-19 69.1 2.0 1.4e-08 34.9 0.9 2.3 2 0 0 2 2 2 2 Caulimovirus viroplasmin Cys_rich_KTR PF14205.6 KIY61039.1 - 0.094 12.5 1.5 4.5 7.1 0.0 2.3 2 0 0 2 2 2 0 Cysteine-rich KTR F-box-like PF12937.7 KIY61040.1 - 0.0024 17.7 4.2 0.01 15.7 4.2 2.1 1 1 0 1 1 1 1 F-box-like LRR_8 PF13855.6 KIY61040.1 - 4.5 7.1 6.8 2.2 8.1 2.1 2.8 3 1 0 3 3 3 0 Leucine rich repeat Kinesin PF00225.23 KIY61043.1 - 6.9e-107 357.2 0.0 1.3e-106 356.3 0.0 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KIY61043.1 - 1.5e-21 76.9 0.0 4.2e-21 75.4 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding Microtub_bind PF13931.6 KIY61043.1 - 0.0003 21.2 0.1 0.0003 21.2 0.1 3.4 5 0 0 5 5 5 1 Kinesin-associated microtubule-binding CdvA PF18822.1 KIY61043.1 - 0.072 12.9 0.1 0.072 12.9 0.1 4.0 3 1 0 3 3 3 0 CdvA-like coiled-coil domain DUF5082 PF16888.5 KIY61043.1 - 0.11 12.7 15.7 1.9 8.8 0.4 5.8 4 2 2 6 6 6 0 Domain of unknown function (DUF5082) Tae4 PF14113.6 KIY61043.1 - 0.22 11.8 2.5 5 7.4 0.1 3.5 3 1 0 3 3 3 0 Type VI secretion system (T6SS), amidase effector protein 4 Fib_alpha PF08702.10 KIY61043.1 - 0.61 10.3 10.4 7.6 6.7 0.1 4.3 3 1 1 4 4 4 0 Fibrinogen alpha/beta chain family DASH_Hsk3 PF08227.11 KIY61043.1 - 4 7.9 6.3 0.59 10.5 0.3 2.5 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like ZapD PF07072.11 KIY61043.1 - 4.2 7.1 6.4 7.2 6.3 0.4 3.1 2 0 0 2 2 2 0 Cell division protein Baculo_PEP_C PF04513.12 KIY61043.1 - 5.3 7.1 13.2 23 5.0 0.1 4.6 4 1 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Stomoxyn PF11585.8 KIY61045.1 - 0.065 13.3 0.2 0.14 12.2 0.2 1.5 1 0 0 1 1 1 0 Insect antimicrobial peptide, stomoxyn OrsD PF12013.8 KIY61047.1 - 1.7e-07 31.7 0.9 1.7e-07 31.7 0.9 2.9 2 1 0 2 2 2 1 Orsellinic acid/F9775 biosynthesis cluster protein D AKAP95 PF04988.12 KIY61047.1 - 0.0091 16.2 7.6 0.45 10.7 0.4 3.6 3 0 0 3 3 3 1 A-kinase anchoring protein 95 (AKAP95) FOXP-CC PF16159.5 KIY61047.1 - 0.023 15.3 6.4 5.4 7.7 0.2 4.1 4 0 0 4 4 4 0 FOXP coiled-coil domain zf-C2H2_12 PF18658.1 KIY61047.1 - 0.41 10.3 2.3 4.1 7.1 0.5 2.6 2 0 0 2 2 2 0 Zinc-finger C2H2-type zf-C2H2_4 PF13894.6 KIY61047.1 - 4.1 8.5 20.9 4.3 8.4 0.9 5.5 5 0 0 5 5 5 0 C2H2-type zinc finger DUF3498 PF12004.8 KIY61049.1 - 0.29 10.3 9.2 0.31 10.2 9.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3498) SHD1 PF03983.12 KIY61051.1 - 0.039 13.8 0.0 0.076 12.8 0.0 1.4 1 0 0 1 1 1 0 SLA1 homology domain 1, SHD1 Helitron_like_N PF14214.6 KIY61052.1 - 2.1e-19 70.5 0.0 2.6e-19 70.2 0.0 1.0 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus gag-asp_proteas PF13975.6 KIY61054.1 - 0.072 13.7 0.0 0.22 12.1 0.0 1.9 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Plavaka PF18759.1 KIY61056.1 - 1.6e-17 63.8 0.1 1.9e-17 63.5 0.1 1.1 1 0 0 1 1 1 1 Plavaka transposase Plavaka PF18759.1 KIY61057.1 - 2.9e-41 141.8 0.0 3.2e-41 141.6 0.0 1.0 1 0 0 1 1 1 1 Plavaka transposase Plavaka PF18759.1 KIY61058.1 - 1.4e-38 132.9 0.4 2.1e-38 132.4 0.4 1.3 1 0 0 1 1 1 1 Plavaka transposase PPP4R2 PF09184.11 KIY61059.1 - 0.056 13.0 11.3 0.077 12.6 11.3 1.1 1 0 0 1 1 1 0 PPP4R2 GEMIN8 PF15348.6 KIY61059.1 - 0.55 10.5 10.5 0.18 12.1 5.1 2.1 2 0 0 2 2 2 0 Gemini of Cajal bodies-associated protein 8 Macoilin PF09726.9 KIY61059.1 - 0.64 8.5 9.4 0.66 8.5 9.4 1.1 1 0 0 1 1 1 0 Macoilin family Spem1 PF15670.5 KIY61059.1 - 0.9 9.1 9.1 0.098 12.2 5.0 1.4 2 0 0 2 2 2 0 Spermatid maturation protein 1 Presenilin PF01080.17 KIY61059.1 - 1.1 7.9 6.1 1.3 7.7 6.1 1.1 1 0 0 1 1 1 0 Presenilin SPX PF03105.19 KIY61059.1 - 1.4 8.7 12.3 1.7 8.4 12.3 1.2 1 0 0 1 1 1 0 SPX domain FYDLN_acid PF09538.10 KIY61059.1 - 2.8 8.7 12.3 2.9 8.6 10.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) DUF2385 PF09539.10 KIY61061.1 - 0.16 12.5 0.0 0.47 11.0 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2385) Plavaka PF18759.1 KIY61062.1 - 1.5e-93 313.6 0.0 1.8e-93 313.3 0.0 1.1 1 0 0 1 1 1 1 Plavaka transposase WD40 PF00400.32 KIY61065.1 - 0.017 16.0 1.1 4.7 8.2 0.1 3.7 2 1 0 2 2 2 0 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY61065.1 - 0.12 12.7 0.1 1.9 8.9 0.0 2.7 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain RRM_1 PF00076.22 KIY61067.1 - 8.3e-17 60.8 0.0 1.1e-16 60.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.11 KIY61067.1 - 0.021 14.5 0.0 0.062 13.0 0.0 1.8 1 0 0 1 1 1 0 Ribonuclease B OB domain zf-HC3 PF16827.5 KIY61070.1 - 0.12 12.6 0.6 1.1 9.5 0.1 2.1 2 0 0 2 2 2 0 zinc-finger RVT_1 PF00078.27 KIY61071.1 - 8.2e-10 38.6 0.0 1.2e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Plavaka PF18759.1 KIY61072.1 - 1.7e-15 57.1 0.0 2.3e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase Plavaka PF18759.1 KIY61073.1 - 1.6e-66 224.8 0.0 1.7e-66 224.6 0.0 1.0 1 0 0 1 1 1 1 Plavaka transposase VMA21 PF09446.10 KIY61073.1 - 0.18 11.9 0.0 0.34 11.1 0.0 1.4 1 0 0 1 1 1 0 VMA21-like domain Plavaka PF18759.1 KIY61074.1 - 1.2e-20 74.1 0.2 1.4e-20 73.8 0.2 1.1 1 0 0 1 1 1 1 Plavaka transposase DDE_Tnp_4 PF13359.6 KIY61076.1 - 2.7e-05 23.9 0.0 4.6e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF357 PF04010.13 KIY61076.1 - 0.1 12.7 0.1 0.19 11.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF357) DDE_Tnp_4 PF13359.6 KIY61077.1 - 0.013 15.1 0.0 0.019 14.7 0.0 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease DDDD PF10161.9 KIY61077.1 - 0.033 13.9 0.3 0.055 13.2 0.3 1.4 1 0 0 1 1 1 0 Putative mitochondrial precursor protein F-box-like PF12937.7 KIY61080.1 - 2.1e-06 27.5 0.4 7.7e-06 25.7 0.4 2.1 1 0 0 1 1 1 1 F-box-like Pyr_redox_2 PF07992.14 KIY61081.1 - 4.3e-65 219.9 5.0 5.6e-65 219.5 5.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KIY61081.1 - 2.4e-43 146.9 2.9 1.7e-42 144.1 0.4 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KIY61081.1 - 1.4e-20 73.6 6.0 5.4e-18 65.3 2.4 3.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KIY61081.1 - 4.3e-10 39.2 1.3 4.3e-10 39.2 1.3 2.9 2 2 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 KIY61081.1 - 9.5e-09 35.4 2.0 0.00014 22.1 0.0 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KIY61081.1 - 1.8e-08 34.2 0.1 1.8e-08 34.2 0.1 3.0 2 1 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KIY61081.1 - 1.7e-07 30.8 5.8 0.00014 21.3 0.1 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KIY61081.1 - 2.8e-07 30.0 0.6 2.8e-07 30.0 0.6 3.5 2 1 2 4 4 4 1 FAD binding domain AlaDh_PNT_C PF01262.21 KIY61081.1 - 5e-07 29.2 5.3 0.0068 15.7 0.8 3.0 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 KIY61081.1 - 2.1e-05 23.4 14.1 0.00017 20.4 0.5 3.9 4 0 0 4 4 4 2 HI0933-like protein K_oxygenase PF13434.6 KIY61081.1 - 0.00011 21.5 1.4 0.51 9.4 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 KIY61081.1 - 0.00016 21.0 2.5 0.0008 18.7 0.0 2.6 3 0 0 3 3 3 1 Thi4 family FAD_binding_3 PF01494.19 KIY61081.1 - 0.00016 21.0 10.4 0.01 15.1 0.2 3.5 3 1 0 3 3 3 2 FAD binding domain THF_DHG_CYH_C PF02882.19 KIY61081.1 - 0.017 14.5 0.0 0.076 12.3 0.1 2.1 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DAO PF01266.24 KIY61081.1 - 0.024 14.3 16.9 0.11 12.0 0.1 3.5 3 1 1 4 4 4 0 FAD dependent oxidoreductase XdhC_C PF13478.6 KIY61081.1 - 0.085 13.4 0.3 21 5.7 0.1 2.7 3 0 0 3 3 3 0 XdhC Rossmann domain Amino_oxidase PF01593.24 KIY61081.1 - 0.16 11.2 0.6 0.39 9.9 0.6 1.5 1 1 0 1 1 1 0 Flavin containing amine oxidoreductase 3HCDH_N PF02737.18 KIY61081.1 - 0.18 11.6 4.3 0.66 9.8 1.0 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 KIY61081.1 - 1.1 8.8 7.5 3.3 7.2 1.4 2.8 2 1 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DDE_Tnp_4 PF13359.6 KIY61083.1 - 2.4e-17 63.0 0.0 3e-17 62.7 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF3338 PF11819.8 KIY61083.1 - 0.11 12.5 0.3 7.3 6.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3338) CsgF PF10614.9 KIY61084.1 - 0.038 14.2 0.0 0.075 13.3 0.0 1.4 1 0 0 1 1 1 0 Type VIII secretion system (T8SS), CsgF protein Retrotran_gag_2 PF14223.6 KIY61085.1 - 0.0092 15.7 0.0 0.016 14.8 0.0 1.5 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type F-box-like PF12937.7 KIY61086.1 - 1.7e-09 37.4 0.3 4.9e-09 36.0 0.3 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY61086.1 - 0.001 18.9 0.3 0.001 18.9 0.3 2.2 2 0 0 2 2 2 1 F-box domain DDE_3 PF13358.6 KIY61088.1 - 0.00014 21.6 0.0 0.0002 21.2 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF4812 PF16071.5 KIY61088.1 - 0.092 12.6 0.1 10 6.0 0.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4812) F-box PF00646.33 KIY61089.1 - 1.2e-06 28.2 0.9 2.1e-06 27.5 0.9 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KIY61089.1 - 0.0002 21.2 1.2 0.00034 20.4 0.7 1.6 2 0 0 2 2 2 1 F-box-like F-box_4 PF15966.5 KIY61089.1 - 0.055 13.4 0.1 0.069 13.0 0.1 1.3 1 0 0 1 1 1 0 F-box Oxysterol_BP PF01237.18 KIY61090.1 - 2.6e-42 145.0 0.0 8.2e-42 143.4 0.0 1.7 1 1 0 1 1 1 1 Oxysterol-binding protein SNF2_N PF00176.23 KIY61092.1 - 1.8e-12 46.7 0.0 3.2e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KIY61092.1 - 9.2e-07 29.2 0.0 1.7e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain 2OG-FeII_Oxy_3 PF13640.6 KIY61094.1 - 0.023 15.6 0.0 0.028 15.3 0.0 1.2 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily DUF659 PF04937.15 KIY61097.1 - 0.00045 20.1 0.7 0.0011 18.8 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) Adhesin_E PF16747.5 KIY61097.1 - 0.037 14.1 0.0 0.053 13.6 0.0 1.3 1 0 0 1 1 1 0 Surface-adhesin protein E MAD PF05557.13 KIY61098.1 - 0.00098 17.6 2.6 0.0012 17.3 2.6 1.0 1 0 0 1 1 1 1 Mitotic checkpoint protein DUF4200 PF13863.6 KIY61098.1 - 0.0018 18.6 3.1 0.0026 18.2 3.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4200) SlyX PF04102.12 KIY61098.1 - 0.011 16.3 1.3 4.2 8.1 0.3 2.4 1 1 1 2 2 2 0 SlyX TMCO5 PF14992.6 KIY61098.1 - 0.018 14.7 0.3 0.023 14.3 0.3 1.1 1 0 0 1 1 1 0 TMCO5 family ABC_tran_CTD PF16326.5 KIY61098.1 - 0.026 14.7 5.2 0.045 14.0 1.2 2.3 2 0 0 2 2 2 0 ABC transporter C-terminal domain HAUS6_N PF14661.6 KIY61098.1 - 0.031 13.9 1.2 0.04 13.5 1.2 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF1664 PF07889.12 KIY61098.1 - 0.04 13.9 0.8 0.059 13.4 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) IFP_35_N PF07334.13 KIY61098.1 - 0.084 13.0 0.1 0.2 11.7 0.1 1.6 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Exonuc_VII_L PF02601.15 KIY61098.1 - 0.14 11.7 1.3 0.18 11.3 1.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF948 PF06103.11 KIY61098.1 - 0.14 12.4 0.0 0.22 11.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF748 PF05359.11 KIY61099.1 - 0.091 12.9 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF748) PRIMA1 PF16101.5 KIY61099.1 - 2.4 8.2 8.2 5.1 7.2 8.2 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 zf-RVT PF13966.6 KIY61100.1 - 0.014 16.1 0.6 0.036 14.8 0.1 1.8 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase DUF2195 PF09961.9 KIY61104.1 - 0.069 13.1 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2195) Myelin_MBP PF01669.17 KIY61105.1 - 0.024 15.2 0.2 1.5 9.4 0.0 2.6 2 0 0 2 2 2 0 Myelin basic protein Retrotran_gag_2 PF14223.6 KIY61106.1 - 2.8e-26 91.8 0.1 4e-26 91.3 0.1 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Glyco_transf_24 PF18404.1 KIY61106.1 - 0.17 11.3 1.1 0.18 11.1 0.1 1.5 2 0 0 2 2 2 0 Glucosyltransferase 24 gag_pre-integrs PF13976.6 KIY61107.1 - 0.016 15.1 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 GAG-pre-integrase domain HSP70 PF00012.20 KIY61109.1 - 1.5e-155 518.8 1.6 1.7e-155 518.6 0.1 1.7 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 KIY61109.1 - 2e-11 43.3 0.0 3.2e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 MreB/Mbl protein DUF4600 PF15372.6 KIY61109.1 - 0.0068 16.8 5.9 1.2 9.6 2.5 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4600) DUF2018 PF09442.10 KIY61109.1 - 0.02 15.8 1.7 13 6.8 0.0 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF2018) Apolipoprotein PF01442.18 KIY61109.1 - 0.41 10.5 6.5 0.48 10.3 0.5 3.0 3 0 0 3 3 3 0 Apolipoprotein A1/A4/E domain HalX PF08663.10 KIY61111.1 - 0.01 16.1 8.3 0.01 16.1 8.3 3.7 2 1 1 3 3 3 0 HalX domain DIMCO_N PF16844.5 KIY61111.1 - 0.017 15.4 8.4 0.16 12.3 1.4 2.6 2 1 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor, N-terminal Pox_A_type_inc PF04508.12 KIY61111.1 - 0.22 11.5 10.9 8.1 6.5 0.2 4.3 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat Laminin_II PF06009.12 KIY61111.1 - 2.2 8.3 19.2 1.2 9.1 0.6 3.4 1 1 2 3 3 3 0 Laminin Domain II HU-CCDC81_bac_2 PF18175.1 KIY61111.1 - 2.9 7.8 6.3 3.3 7.6 0.5 3.2 2 1 1 3 3 3 0 CCDC81-like prokaryotic HU domain 2 Erp_C PF06780.11 KIY61111.1 - 5.4 7.0 8.6 6.8 6.7 0.4 3.2 1 1 1 3 3 3 0 Erp protein C-terminus Putative_G5P PF17426.2 KIY61112.1 - 0.15 12.2 0.0 0.28 11.3 0.0 1.3 1 0 0 1 1 1 0 Putative Gamma DNA binding protein G5P EMC3_TMCO1 PF01956.16 KIY61112.1 - 0.27 11.0 0.7 0.47 10.2 0.7 1.3 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Tau95 PF09734.9 KIY61113.1 - 0.034 14.9 0.2 0.076 13.8 0.2 1.7 1 1 0 1 1 1 0 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain DUF2976 PF11190.8 KIY61114.1 - 0.14 12.0 0.2 0.2 11.5 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2976) Cauli_VI PF01693.16 KIY61115.1 - 6.1e-05 23.2 0.0 0.0013 19.0 0.0 2.5 2 0 0 2 2 2 1 Caulimovirus viroplasmin Transposase_21 PF02992.14 KIY61116.1 - 1.6e-06 27.6 0.0 2.8e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 Chorion_S16 PF05836.12 KIY61116.1 - 0.15 12.3 0.3 0.45 10.8 0.3 1.8 1 0 0 1 1 1 0 Chorion protein S16 EzrA PF06160.12 KIY61119.1 - 5.4e-05 21.6 3.8 6.5e-05 21.3 3.8 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA IFT57 PF10498.9 KIY61119.1 - 0.00014 20.9 5.3 0.00018 20.6 5.3 1.1 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 GAS PF13851.6 KIY61119.1 - 0.00059 19.2 12.5 0.0012 18.2 12.5 1.4 1 1 0 1 1 1 1 Growth-arrest specific micro-tubule binding ADIP PF11559.8 KIY61119.1 - 0.0014 18.7 7.7 0.0027 17.8 7.7 1.4 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Spc7 PF08317.11 KIY61119.1 - 0.0015 17.5 10.5 0.0024 16.8 10.5 1.4 1 1 0 1 1 1 1 Spc7 kinetochore protein Tup_N PF08581.10 KIY61119.1 - 0.0034 17.6 5.0 0.0037 17.5 3.7 1.7 1 1 0 1 1 1 1 Tup N-terminal KASH_CCD PF14662.6 KIY61119.1 - 0.0037 17.1 8.2 0.0055 16.6 8.2 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH Laminin_I PF06008.14 KIY61119.1 - 0.004 16.9 2.7 0.0054 16.5 2.7 1.2 1 0 0 1 1 1 1 Laminin Domain I MbeD_MobD PF04899.12 KIY61119.1 - 0.0058 16.7 1.8 0.0058 16.7 1.8 2.1 2 1 0 2 2 2 1 MbeD/MobD like CENP-H PF05837.12 KIY61119.1 - 0.0069 16.8 3.8 0.0069 16.8 3.8 1.8 1 1 0 2 2 1 1 Centromere protein H (CENP-H) DUF4472 PF14739.6 KIY61119.1 - 0.008 16.9 0.7 0.008 16.9 0.7 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF4472) HALZ PF02183.18 KIY61119.1 - 0.0085 16.3 7.2 0.0085 16.3 7.2 2.6 2 1 1 3 3 3 1 Homeobox associated leucine zipper HAUS-augmin3 PF14932.6 KIY61119.1 - 0.0091 15.6 4.3 0.015 14.9 4.3 1.4 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 3 DUF4407 PF14362.6 KIY61119.1 - 0.0097 15.3 2.2 0.011 15.1 2.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) ATG16 PF08614.11 KIY61119.1 - 0.011 15.9 10.2 0.017 15.3 10.2 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) STAT_alpha PF01017.20 KIY61119.1 - 0.012 15.5 4.9 0.022 14.6 4.9 1.4 1 0 0 1 1 1 0 STAT protein, all-alpha domain ZapB PF06005.12 KIY61119.1 - 0.013 15.9 12.4 0.22 12.0 10.9 2.3 1 1 1 2 2 2 0 Cell division protein ZapB T3SSipB PF16535.5 KIY61119.1 - 0.014 15.9 0.2 0.022 15.2 0.2 1.3 1 0 0 1 1 1 0 Type III cell invasion protein SipB LPP PF04728.13 KIY61119.1 - 0.016 15.5 6.4 0.85 10.1 0.7 3.1 2 1 1 3 3 3 0 Lipoprotein leucine-zipper OmpH PF03938.14 KIY61119.1 - 0.018 15.4 6.0 0.029 14.7 6.0 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) SHE3 PF17078.5 KIY61119.1 - 0.018 14.8 8.1 0.032 14.0 8.1 1.4 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 Cep57_MT_bd PF06657.13 KIY61119.1 - 0.021 15.3 3.5 0.073 13.5 3.3 2.0 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Seryl_tRNA_N PF02403.22 KIY61119.1 - 0.022 15.0 9.2 0.026 14.7 8.0 1.7 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Fez1 PF06818.15 KIY61119.1 - 0.024 15.1 7.5 0.024 15.1 7.5 1.5 1 1 1 2 2 1 0 Fez1 JAKMIP_CC3 PF16034.5 KIY61119.1 - 0.024 14.6 8.3 0.03 14.3 6.8 1.9 1 1 0 1 1 1 0 JAKMIP CC3 domain Tropomyosin_1 PF12718.7 KIY61119.1 - 0.024 14.8 11.8 0.032 14.4 11.1 1.5 1 1 0 1 1 1 0 Tropomyosin like PI3K_P85_iSH2 PF16454.5 KIY61119.1 - 0.027 14.1 9.7 0.061 12.9 0.9 2.2 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain SKA2 PF16740.5 KIY61119.1 - 0.031 14.1 4.2 0.28 11.0 4.1 2.4 1 1 2 3 3 3 0 Spindle and kinetochore-associated protein 2 TACC_C PF05010.14 KIY61119.1 - 0.034 13.9 7.4 0.066 13.0 7.4 1.4 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal FapA PF03961.13 KIY61119.1 - 0.037 12.6 5.8 0.049 12.2 5.8 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Taxilin PF09728.9 KIY61119.1 - 0.043 13.0 9.1 0.058 12.6 9.1 1.2 1 0 0 1 1 1 0 Myosin-like coiled-coil protein CENP-F_leu_zip PF10473.9 KIY61119.1 - 0.055 13.5 11.6 0.18 11.9 11.6 1.7 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3450 PF11932.8 KIY61119.1 - 0.055 12.8 7.0 0.094 12.0 6.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) TMPIT PF07851.13 KIY61119.1 - 0.062 12.5 4.3 0.12 11.6 4.5 1.3 1 1 0 1 1 1 0 TMPIT-like protein Atg14 PF10186.9 KIY61119.1 - 0.065 12.3 6.8 0.1 11.7 6.8 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Uds1 PF15456.6 KIY61119.1 - 0.073 13.2 5.2 0.047 13.9 3.2 1.6 2 0 0 2 2 1 0 Up-regulated During Septation Med30 PF11315.8 KIY61119.1 - 0.078 13.2 5.4 0.11 12.7 5.4 1.2 1 0 0 1 1 1 0 Mediator complex subunit 30 Scaffolding_pro PF11418.8 KIY61119.1 - 0.078 13.5 1.5 0.12 12.9 1.3 1.4 1 1 0 1 1 1 0 Phi29 scaffolding protein K-box PF01486.17 KIY61119.1 - 0.081 13.1 8.9 0.076 13.2 6.5 2.1 2 0 0 2 2 2 0 K-box region Mod_r PF07200.13 KIY61119.1 - 0.1 12.7 7.2 1.2 9.2 6.2 2.2 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Occludin_ELL PF07303.13 KIY61119.1 - 0.11 13.3 6.9 0.083 13.6 3.6 2.0 1 1 1 2 2 2 0 Occludin homology domain IATP PF04568.12 KIY61119.1 - 0.12 12.8 0.0 0.12 12.8 0.0 2.6 2 1 1 3 3 3 0 Mitochondrial ATPase inhibitor, IATP DUF1664 PF07889.12 KIY61119.1 - 0.12 12.4 1.9 4.2 7.4 1.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) CorA PF01544.18 KIY61119.1 - 0.14 11.4 0.6 0.23 10.7 0.6 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein KAR9 PF08580.10 KIY61119.1 - 0.16 10.5 3.9 0.11 11.1 1.6 1.6 1 1 1 2 2 2 0 Yeast cortical protein KAR9 Prominin PF05478.11 KIY61119.1 - 0.17 9.8 2.4 0.22 9.5 2.4 1.1 1 0 0 1 1 1 0 Prominin TPR_MLP1_2 PF07926.12 KIY61119.1 - 0.22 11.6 10.9 1.2 9.2 10.7 2.5 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Syntaxin_2 PF14523.6 KIY61119.1 - 0.22 11.9 6.1 2.2 8.7 6.1 2.2 1 1 0 1 1 1 0 Syntaxin-like protein GIT_CC PF16559.5 KIY61119.1 - 0.23 11.4 6.7 7.4 6.5 1.0 3.4 1 1 2 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor YabA PF06156.13 KIY61119.1 - 0.26 11.9 8.2 0.41 11.3 7.2 1.9 1 1 0 1 1 1 0 Initiation control protein YabA V_ATPase_I PF01496.19 KIY61119.1 - 0.26 9.1 2.4 0.31 8.9 2.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Exonuc_VII_L PF02601.15 KIY61119.1 - 0.34 10.4 3.2 0.42 10.1 3.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DHR10 PF18595.1 KIY61119.1 - 0.35 11.0 11.4 11 6.1 11.1 2.2 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain DUF4795 PF16043.5 KIY61119.1 - 0.47 10.0 7.8 0.77 9.3 7.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) JIP_LZII PF16471.5 KIY61119.1 - 0.51 10.5 10.8 35 4.7 6.2 3.1 1 1 2 3 3 3 0 JNK-interacting protein leucine zipper II DASH_Dam1 PF08653.10 KIY61119.1 - 0.51 10.2 3.8 26 4.7 0.3 3.4 1 1 3 4 4 4 0 DASH complex subunit Dam1 APG6_N PF17675.1 KIY61119.1 - 0.6 10.6 11.5 1.5 9.4 11.5 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF4201 PF13870.6 KIY61119.1 - 0.62 9.8 13.0 3.8 7.2 12.4 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) Prefoldin_2 PF01920.20 KIY61119.1 - 0.62 10.0 11.6 0.14 12.1 3.3 2.5 1 1 1 2 2 2 0 Prefoldin subunit Cep57_CLD_2 PF14197.6 KIY61119.1 - 0.63 10.2 9.4 1.6 8.8 4.4 2.6 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 DUF4298 PF14131.6 KIY61119.1 - 0.68 9.9 6.3 0.37 10.8 3.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4298) KELK PF15796.5 KIY61119.1 - 0.8 10.2 13.9 0.51 10.8 9.2 2.4 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Phlebovirus_NSM PF07246.11 KIY61119.1 - 0.89 8.9 9.4 0.42 9.9 5.8 1.8 1 1 0 2 2 2 0 Phlebovirus nonstructural protein NS-M UPF0515 PF15135.6 KIY61119.1 - 0.91 8.8 5.6 0.19 11.1 0.7 2.0 2 0 0 2 2 2 0 Uncharacterised protein UPF0515 DUF724 PF05266.14 KIY61119.1 - 0.99 9.2 6.5 2.2 8.1 6.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Syntaxin-6_N PF09177.11 KIY61119.1 - 1 10.0 4.4 2.7 8.6 3.7 1.9 1 1 0 1 1 1 0 Syntaxin 6, N-terminal UPF0242 PF06785.11 KIY61119.1 - 1.1 9.3 9.5 1.9 8.6 9.5 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Cnn_1N PF07989.11 KIY61119.1 - 1.2 9.4 13.2 6.4e+02 0.6 13.3 3.0 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 Nup54 PF13874.6 KIY61119.1 - 1.2 9.2 6.6 1.7 8.8 0.9 2.2 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 TolA_bind_tri PF16331.5 KIY61119.1 - 1.2 9.2 9.4 3.4 7.8 7.4 2.5 1 1 2 3 3 3 0 TolA binding protein trimerisation Com_YlbF PF06133.11 KIY61119.1 - 1.2 9.7 9.3 3.6 8.3 8.8 2.0 1 1 0 1 1 1 0 Control of competence regulator ComK, YlbF/YmcA DUF1640 PF07798.11 KIY61119.1 - 1.4 9.0 10.2 2.9 7.9 10.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) KxDL PF10241.9 KIY61119.1 - 1.5 9.2 8.2 2.4 8.5 3.9 2.7 1 1 2 3 3 3 0 Uncharacterized conserved protein DUF4446 PF14584.6 KIY61119.1 - 1.5 8.8 6.2 6.5 6.7 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) GrpE PF01025.19 KIY61119.1 - 1.5 8.4 11.5 0.48 10.1 5.8 2.2 1 1 1 2 2 2 0 GrpE GreA_GreB_N PF03449.15 KIY61119.1 - 1.6 8.9 8.4 8 6.7 0.5 3.2 3 1 0 3 3 2 0 Transcription elongation factor, N-terminal Spc24 PF08286.11 KIY61119.1 - 3.7 7.9 8.2 6.3 7.1 6.6 2.1 1 1 0 2 2 1 0 Spc24 subunit of Ndc80 bZIP_1 PF00170.21 KIY61119.1 - 3.8 7.7 15.3 0.66 10.1 2.7 3.2 2 1 1 3 3 3 0 bZIP transcription factor DUF848 PF05852.11 KIY61119.1 - 5 7.2 7.3 5.2 7.2 4.4 1.9 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Rib_recp_KP_reg PF05104.12 KIY61120.1 - 7.9 7.5 8.1 1 10.4 3.2 1.9 2 1 0 2 2 2 0 Ribosome receptor lysine/proline rich region Peptidase_C48 PF02902.19 KIY61123.1 - 6.2e-25 88.3 0.1 8.8e-25 87.8 0.1 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain HMG_box PF00505.19 KIY61128.1 - 0.071 13.5 2.4 0.083 13.3 0.9 1.9 2 0 0 2 2 2 0 HMG (high mobility group) box RNase_II_C_S1 PF18614.1 KIY61130.1 - 0.13 12.2 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 RNase II-type exonuclease C-terminal S1 domain KDZ PF18758.1 KIY61132.1 - 3.3e-45 154.4 0.1 4.4e-45 154.0 0.1 1.2 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KIY61132.1 - 7e-08 32.6 1.4 2.6e-07 30.8 0.1 2.3 2 0 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases DDE_3 PF13358.6 KIY61133.1 - 1.3e-08 34.8 0.9 1.6e-08 34.4 0.9 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.26 KIY61133.1 - 0.077 13.2 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Integrase core domain Baculo_PEP_C PF04513.12 KIY61135.1 - 0.025 14.6 5.9 0.83 9.7 0.2 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus CHDCT2 PF08074.11 KIY61135.1 - 0.04 14.1 0.3 0.76 9.9 0.0 2.3 1 1 1 2 2 2 0 CHDCT2 (NUC038) domain BURP PF03181.15 KIY61137.1 - 0.045 13.3 0.2 0.15 11.6 0.0 2.0 3 0 0 3 3 3 0 BURP domain Alpha_kinase PF02816.18 KIY61140.1 - 1.9e-13 51.0 0.1 3.2e-13 50.2 0.1 1.3 1 0 0 1 1 1 1 Alpha-kinase family Kp4 PF09044.10 KIY61140.1 - 0.15 12.2 1.7 0.31 11.1 1.7 1.5 1 0 0 1 1 1 0 Kp4 OPT PF03169.15 KIY61141.1 - 2.7e-10 39.5 0.4 3.5e-10 39.2 0.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein F-box-like PF12937.7 KIY61144.1 - 0.0001 22.1 0.0 0.00029 20.7 0.0 1.8 1 0 0 1 1 1 1 F-box-like GHMP_kinases_C PF08544.13 KIY61145.1 - 2.1e-06 28.0 0.1 4.8e-06 26.9 0.1 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal Dimer_Tnp_hAT PF05699.14 KIY61148.1 - 7e-21 73.8 0.1 1.1e-20 73.2 0.1 1.3 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.6 KIY61149.1 - 0.11 12.9 0.2 0.25 11.7 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4413) DUF659 PF04937.15 KIY61150.1 - 0.00099 19.0 0.0 0.0015 18.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) LAGLIDADG_3 PF14528.6 KIY61150.1 - 0.072 13.4 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 LAGLIDADG-like domain zf-CCHC PF00098.23 KIY61154.1 - 0.017 15.2 2.2 0.11 12.6 2.2 2.2 1 1 0 1 1 1 0 Zinc knuckle RVT_thumb PF06817.14 KIY61156.1 - 0.036 13.9 0.0 0.059 13.2 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase thumb domain DEAD PF00270.29 KIY61158.1 - 0.0023 17.7 0.0 0.0032 17.2 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 KIY61158.1 - 0.019 14.7 0.0 0.025 14.3 0.0 1.2 1 0 0 1 1 1 0 SWI2/SNF2 ATPase Acid_PPase PF12689.7 KIY61158.1 - 0.13 12.2 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Acid Phosphatase Plavaka PF18759.1 KIY61165.1 - 1.1e-41 143.2 0.0 1.5e-41 142.7 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase Herpes_UL25 PF01499.16 KIY61168.1 - 0.63 8.5 10.1 0.71 8.3 9.1 1.5 1 1 0 1 1 1 0 Herpesvirus UL25 family T6SS_VipA PF05591.12 KIY61168.1 - 4.7 7.0 10.1 7.3 6.4 0.7 3.3 3 0 0 3 3 3 0 Type VI secretion system, VipA, VC_A0107 or Hcp2 CUE PF02845.16 KIY61169.1 - 1.9e-11 43.4 0.0 3.3e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 CUE domain Cue1_U7BR PF18499.1 KIY61169.1 - 0.1 12.6 3.5 0.69 10.0 3.5 2.0 1 1 0 1 1 1 0 Ubc7p-binding region of Cue1 Asp PF00026.23 KIY61170.1 - 6.7e-40 137.4 0.0 9.3e-40 137.0 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIY61170.1 - 7.9e-05 23.0 2.0 0.16 12.2 0.1 2.3 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KIY61170.1 - 0.012 16.3 0.2 0.11 13.2 0.0 2.6 3 1 0 3 3 3 0 Aspartyl protease gag-asp_proteas PF13975.6 KIY61170.1 - 0.092 13.3 0.0 0.47 11.0 0.0 2.2 1 1 0 1 1 1 0 gag-polyprotein putative aspartyl protease zf-C3H1 PF10650.9 KIY61170.1 - 0.12 12.1 0.2 0.22 11.3 0.2 1.4 1 0 0 1 1 1 0 Putative zinc-finger domain PhyH PF05721.13 KIY61171.1 - 4.1e-09 37.0 0.0 6.5e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 KIY61171.1 - 0.024 15.0 0.0 0.047 14.1 0.0 1.5 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase Ima1_N PF09779.9 KIY61174.1 - 8.4 7.3 8.3 4.9 8.0 5.5 2.1 1 1 1 2 2 2 0 Ima1 N-terminal domain Astro_capsid_p PF12226.8 KIY61175.1 - 0.18 10.9 1.6 0.33 10.1 1.6 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Cauli_VI PF01693.16 KIY61176.1 - 7.8e-08 32.5 0.1 1.8e-07 31.3 0.1 1.6 1 0 0 1 1 1 1 Caulimovirus viroplasmin CxC2 PF18803.1 KIY61177.1 - 2.5e-34 117.7 0.0 3.6e-34 117.1 0.0 1.2 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases KDZ PF18758.1 KIY61177.1 - 1.3e-09 38.0 0.0 1.9e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 KIY61177.1 - 0.00021 21.4 0.0 0.00032 20.8 0.0 1.3 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases SNF2_N PF00176.23 KIY61178.1 - 3.8e-18 65.3 0.0 6.3e-18 64.6 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KIY61178.1 - 1.3e-08 35.2 0.0 2.5e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CYYR1 PF10873.8 KIY61178.1 - 3 8.3 3.7 11 6.4 3.7 2.0 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 Phage_integrase PF00589.22 KIY61179.1 - 7e-06 25.9 0.0 1.5e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Phage integrase family tRNA_synt_1c_R2 PF04557.15 KIY61179.1 - 0.036 15.0 0.6 0.072 14.0 0.6 1.5 1 0 0 1 1 1 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Zn_clus PF00172.18 KIY61181.1 - 0.033 14.3 7.6 0.37 11.0 1.8 2.3 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 KIY61182.1 - 3.2e-10 40.0 6.9 4.6e-10 39.5 6.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 KIY61185.1 - 0.0032 17.5 9.7 0.034 14.3 3.3 2.2 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain KDZ PF18758.1 KIY61186.1 - 1.6e-47 162.0 0.0 2.7e-47 161.3 0.0 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KIY61186.1 - 1.4e-31 108.9 0.1 3.7e-31 107.5 0.1 1.8 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases Transposase_21 PF02992.14 KIY61189.1 - 8.1e-10 38.3 0.0 1.5e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.6 KIY61190.1 - 3.6e-06 26.6 0.0 6.2e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Cohesin PF00963.18 KIY61191.1 - 0.088 13.0 0.0 0.12 12.6 0.0 1.1 1 0 0 1 1 1 0 Cohesin domain NMO PF03060.15 KIY61193.1 - 3.2e-39 135.2 8.9 6.4e-37 127.7 8.9 2.3 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KIY61193.1 - 1.8e-11 43.6 2.5 2.5e-11 43.2 2.5 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KIY61193.1 - 1.7e-08 33.9 3.6 1.7e-08 33.9 3.6 1.9 2 0 0 2 2 2 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KIY61193.1 - 0.037 13.2 11.4 0.059 12.5 10.1 2.0 1 1 1 2 2 2 0 Conserved region in glutamate synthase NanE PF04131.14 KIY61193.1 - 0.14 11.3 1.1 0.31 10.2 1.1 1.6 1 1 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase Pkinase PF00069.25 KIY61194.1 - 4.1e-35 121.4 0.0 7.4e-35 120.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY61194.1 - 9.5e-33 113.6 0.0 1.4e-32 113.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIY61194.1 - 0.00013 20.9 0.0 0.00022 20.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase SpvB PF03534.13 KIY61194.1 - 0.12 11.5 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Salmonella virulence plasmid 65kDa B protein WD40 PF00400.32 KIY61197.1 - 7.3e-30 102.6 22.9 7.1e-05 23.5 0.2 10.6 10 0 0 10 10 10 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY61197.1 - 8.3e-23 80.5 0.5 3e-05 24.2 0.0 7.0 3 2 4 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain RAB3GAP2_N PF14655.6 KIY61197.1 - 3.8e-05 23.1 0.0 0.008 15.5 0.0 2.7 3 0 0 3 3 3 1 Rab3 GTPase-activating protein regulatory subunit N-terminus Ge1_WD40 PF16529.5 KIY61197.1 - 0.0016 17.5 0.6 0.23 10.4 0.0 3.6 4 0 0 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein IKI3 PF04762.12 KIY61197.1 - 0.004 15.2 0.1 0.48 8.4 0.0 2.7 3 0 0 3 3 3 2 IKI3 family Nup160 PF11715.8 KIY61197.1 - 0.0092 14.7 4.0 0.017 13.8 1.7 2.3 2 1 2 4 4 4 1 Nucleoporin Nup120/160 WD40_like PF17005.5 KIY61197.1 - 0.014 14.7 0.0 3 7.1 0.0 3.2 2 1 2 4 4 4 0 WD40-like domain PQQ_3 PF13570.6 KIY61197.1 - 0.016 15.7 5.5 56 4.4 0.1 6.1 7 0 0 7 7 6 0 PQQ-like domain CPSF_A PF03178.15 KIY61197.1 - 0.037 13.4 0.0 27 3.9 0.0 3.2 2 1 1 3 3 3 0 CPSF A subunit region S1_2 PF13509.6 KIY61197.1 - 0.05 13.7 0.0 7.4 6.7 0.0 2.9 2 0 0 2 2 2 0 S1 domain PQQ_2 PF13360.6 KIY61197.1 - 0.13 11.8 10.3 0.73 9.4 3.6 3.5 2 1 1 3 3 3 0 PQQ-like domain PD40 PF07676.12 KIY61197.1 - 0.18 11.8 2.7 4.5 7.3 0.0 3.2 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat PfkB PF00294.24 KIY61198.1 - 2e-29 102.9 0.0 3.8e-29 102.0 0.0 1.5 1 1 0 1 1 1 1 pfkB family carbohydrate kinase ESX-1_EspG PF14011.6 KIY61198.1 - 0.014 15.1 0.6 0.014 15.1 0.6 2.5 2 1 0 2 2 2 0 EspG family MRP-S25 PF13741.6 KIY61199.1 - 1.5e-44 152.3 3.1 2.9e-44 151.4 3.1 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 zf-ZPR1 PF03367.13 KIY61200.1 - 0.0034 17.3 0.0 0.0048 16.8 0.0 1.1 1 0 0 1 1 1 1 ZPR1 zinc-finger domain p450 PF00067.22 KIY61202.1 - 6.4e-42 143.9 0.0 1.1e-41 143.0 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 COE1_HLH PF16423.5 KIY61202.1 - 0.033 13.9 0.0 2.8 7.7 0.0 2.4 2 0 0 2 2 2 0 Transcription factor COE1 helix-loop-helix domain Nop14 PF04147.12 KIY61203.1 - 0.065 11.4 6.3 0.072 11.3 6.3 1.1 1 0 0 1 1 1 0 Nop14-like family Transposase_21 PF02992.14 KIY61204.1 - 4e-08 32.8 0.0 9.6e-08 31.5 0.0 1.5 2 0 0 2 2 2 1 Transposase family tnp2 Plavaka PF18759.1 KIY61204.1 - 2.4e-06 27.0 0.1 3.9e-06 26.3 0.1 1.2 1 0 0 1 1 1 1 Plavaka transposase DUF1258 PF06869.12 KIY61204.1 - 0.028 13.9 0.0 0.045 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1258) TSGP1 PF07771.11 KIY61206.1 - 0.031 14.4 0.2 0.064 13.4 0.2 1.5 1 0 0 1 1 1 0 Tick salivary peptide group 1 RVT_thumb PF06817.14 KIY61209.1 - 0.0036 17.1 0.0 0.0051 16.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase thumb domain NTF-like PF14540.6 KIY61210.1 - 0.18 11.6 0.1 0.28 11.0 0.1 1.2 1 0 0 1 1 1 0 Nucleotidyltransferase-like KDZ PF18758.1 KIY61212.1 - 5.3e-49 166.8 0.2 8.5e-49 166.2 0.2 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KIY61212.1 - 9.3e-29 99.7 0.0 3.3e-28 98.0 0.0 2.0 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases Phe_tRNA-synt_N PF02912.18 KIY61212.1 - 3.4 7.7 6.0 1.5 8.8 1.4 2.4 2 0 0 2 2 2 0 Aminoacyl tRNA synthetase class II, N-terminal domain RT_RNaseH PF17917.1 KIY61214.1 - 2.4e-05 24.6 0.0 2.7e-05 24.4 0.0 1.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_3 PF13456.6 KIY61214.1 - 0.011 15.5 0.0 0.014 15.2 0.0 1.1 1 0 0 1 1 1 0 Reverse transcriptase-like RT_RNaseH_2 PF17919.1 KIY61214.1 - 0.16 12.0 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase Histone_H2A_C PF16211.5 KIY61215.1 - 0.38 10.5 2.3 0.5 10.1 0.0 2.1 2 0 0 2 2 2 0 C-terminus of histone H2A Nha1_C PF08619.10 KIY61216.1 - 0.12 11.6 25.1 0.17 11.1 11.6 2.1 2 0 0 2 2 2 0 Alkali metal cation/H+ antiporter Nha1 C terminus Apt1 PF10351.9 KIY61216.1 - 4 6.2 18.4 0.069 12.0 6.5 2.0 2 0 0 2 2 2 0 Golgi-body localisation protein domain Retrotran_gag_2 PF14223.6 KIY61218.1 - 0.00031 20.4 0.2 0.00061 19.5 0.2 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Myb_DNA-bind_2 PF08914.11 KIY61218.1 - 0.13 12.4 0.0 10 6.4 0.0 2.7 2 0 0 2 2 2 0 Rap1 Myb domain Abhydrolase_1 PF00561.20 KIY61220.1 - 8e-21 74.8 0.0 2.1e-19 70.2 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 KIY61220.1 - 9.7e-19 67.4 0.0 2.9e-18 65.9 0.0 1.8 2 0 0 2 2 2 1 TAP-like protein PC_rep PF01851.22 KIY61220.1 - 0.27 11.7 0.8 15 6.3 0.6 2.9 2 0 0 2 2 2 0 Proteasome/cyclosome repeat Abhydrolase_1 PF00561.20 KIY61221.1 - 1.1e-22 80.9 0.0 6.2e-20 71.9 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 KIY61221.1 - 7.9e-18 64.5 0.0 1.3e-17 63.8 0.0 1.3 1 0 0 1 1 1 1 TAP-like protein OrsD PF12013.8 KIY61223.1 - 1.9e-05 25.0 0.7 4.7e-05 23.8 0.7 1.7 1 0 0 1 1 1 1 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_4 PF13894.6 KIY61223.1 - 0.064 14.1 3.1 0.9 10.6 0.5 3.5 2 0 0 2 2 2 0 C2H2-type zinc finger IL34 PF15036.6 KIY61229.1 - 0.027 14.5 0.0 0.051 13.6 0.0 1.3 1 0 0 1 1 1 0 Interleukin 34 Cytotoxic PF09000.10 KIY61231.1 - 0.86 10.0 4.9 1.9 8.9 4.9 1.5 1 0 0 1 1 1 0 Cytotoxic PQQ_2 PF13360.6 KIY61235.1 - 0.012 15.3 0.1 0.27 10.8 0.1 2.5 1 1 0 1 1 1 0 PQQ-like domain ATP-synt_ab PF00006.25 KIY61236.1 - 2.3e-108 360.8 0.0 3.1e-108 360.3 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 KIY61236.1 - 6.3e-44 148.7 0.0 1.1e-43 147.9 0.0 1.4 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 KIY61236.1 - 2.2e-15 56.9 3.7 6e-15 55.5 3.7 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA PF00004.29 KIY61237.1 - 3e-41 140.9 0.0 6e-41 140.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KIY61237.1 - 1e-05 25.2 0.1 2.2e-05 24.1 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KIY61237.1 - 4.4e-05 23.5 0.0 0.00015 21.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KIY61237.1 - 7.7e-05 23.0 0.0 0.0045 17.3 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.14 KIY61237.1 - 0.00025 21.2 0.0 0.00076 19.6 0.0 1.8 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KIY61237.1 - 0.00054 20.4 0.1 0.016 15.6 0.1 2.6 1 1 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 KIY61237.1 - 0.00084 18.6 0.0 0.0015 17.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 KIY61237.1 - 0.0038 17.0 0.0 0.015 15.1 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KIY61237.1 - 0.011 15.9 0.0 0.035 14.3 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_28 PF13521.6 KIY61237.1 - 0.012 15.8 0.0 0.024 14.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KIY61237.1 - 0.013 15.1 0.0 0.032 13.8 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region Tir_receptor_N PF07490.11 KIY61237.1 - 0.024 14.5 0.0 0.041 13.7 0.0 1.3 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) N-terminus Sigma54_activ_2 PF14532.6 KIY61237.1 - 0.041 14.0 0.0 0.17 12.0 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_3 PF07726.11 KIY61237.1 - 0.047 13.5 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.13 KIY61237.1 - 0.055 12.7 0.0 0.12 11.5 0.0 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain IstB_IS21 PF01695.17 KIY61237.1 - 0.056 13.2 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.6 KIY61237.1 - 0.059 13.9 0.0 0.15 12.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KIY61237.1 - 0.061 12.7 0.0 0.16 11.4 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ATPase_2 PF01637.18 KIY61237.1 - 0.096 12.6 0.4 31 4.4 0.0 2.9 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 KIY61237.1 - 0.099 12.4 0.1 0.64 9.7 0.0 2.4 2 1 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 KIY61237.1 - 0.13 11.9 0.0 0.33 10.6 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain RNA_helicase PF00910.22 KIY61237.1 - 0.13 12.6 0.0 0.3 11.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase PRK PF00485.18 KIY61243.1 - 0.16 11.7 0.0 0.26 11.0 0.0 1.2 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family KDZ PF18758.1 KIY61244.1 - 1.7e-42 145.6 0.0 6e-42 143.8 0.0 1.9 1 1 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KIY61244.1 - 3.6e-29 101.1 0.0 9.9e-29 99.6 0.0 1.8 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases DUF1248 PF06852.12 KIY61244.1 - 0.13 11.7 0.1 0.27 10.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1248) CDC45 PF02724.14 KIY61245.1 - 0.016 13.5 5.4 0.015 13.6 5.4 1.0 1 0 0 1 1 1 0 CDC45-like protein DDRGK PF09756.9 KIY61245.1 - 0.31 10.6 11.5 0.41 10.2 11.5 1.1 1 0 0 1 1 1 0 DDRGK domain Rrn6 PF10214.9 KIY61245.1 - 0.78 8.2 9.4 0.83 8.1 9.4 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor NARP1 PF12569.8 KIY61245.1 - 7.2 5.4 8.6 9.1 5.1 8.6 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Esterase PF00756.20 KIY61251.1 - 0.11 12.1 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 Putative esterase HA2 PF04408.23 KIY61252.1 - 2.5e-15 56.7 2.7 6.2e-15 55.4 0.0 2.8 3 0 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KIY61252.1 - 4.3e-15 55.8 0.0 1.3e-14 54.3 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KIY61252.1 - 3.6e-12 46.6 0.0 9.7e-12 45.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain FapA PF03961.13 KIY61254.1 - 0.0049 15.5 4.7 0.0049 15.5 4.7 1.4 2 0 0 2 2 2 1 Flagellar Assembly Protein A TolA_bind_tri PF16331.5 KIY61254.1 - 0.0049 16.9 7.2 0.0049 16.9 7.2 2.6 2 1 0 2 2 2 1 TolA binding protein trimerisation Gp58 PF07902.11 KIY61254.1 - 0.0076 14.6 2.4 0.01 14.2 2.4 1.2 1 0 0 1 1 1 1 gp58-like protein NleF_casp_inhib PF16809.5 KIY61254.1 - 0.034 14.0 1.2 0.034 14.0 1.2 1.9 2 0 0 2 2 2 0 NleF caspase inhibitor Uso1_p115_C PF04871.13 KIY61254.1 - 0.09 13.1 14.5 1.4 9.3 8.2 3.0 2 1 1 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region FAM76 PF16046.5 KIY61254.1 - 0.099 12.0 5.2 0.15 11.4 5.2 1.3 1 0 0 1 1 1 0 FAM76 protein KxDL PF10241.9 KIY61254.1 - 0.13 12.5 9.2 10 6.5 7.3 3.0 2 1 0 2 2 2 0 Uncharacterized conserved protein DUF1664 PF07889.12 KIY61254.1 - 0.14 12.2 7.2 0.31 11.1 3.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Bac_GDH PF05088.12 KIY61254.1 - 0.18 9.3 4.0 0.23 8.9 4.0 1.1 1 0 0 1 1 1 0 Bacterial NAD-glutamate dehydrogenase DUF1043 PF06295.12 KIY61254.1 - 0.21 11.6 6.1 0.29 11.1 5.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) DUF1690 PF07956.11 KIY61254.1 - 0.29 11.6 8.2 0.25 11.7 5.9 1.9 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) HAUS-augmin3 PF14932.6 KIY61254.1 - 0.29 10.7 10.9 0.049 13.2 6.3 1.8 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 Spc7 PF08317.11 KIY61254.1 - 0.41 9.5 15.7 0.064 12.1 11.8 1.5 2 0 0 2 2 2 0 Spc7 kinetochore protein SHE3 PF17078.5 KIY61254.1 - 0.53 10.0 10.7 1.4 8.6 10.6 1.8 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 PP28 PF10252.9 KIY61254.1 - 0.64 10.5 9.2 2.5 8.6 8.6 2.2 1 1 1 2 2 2 0 Casein kinase substrate phosphoprotein PP28 Syntaxin_2 PF14523.6 KIY61254.1 - 0.66 10.4 8.7 0.41 11.1 6.5 1.8 2 0 0 2 2 1 0 Syntaxin-like protein CorA PF01544.18 KIY61254.1 - 1.1 8.4 9.8 0.59 9.4 6.9 1.9 2 1 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF4201 PF13870.6 KIY61254.1 - 1.3 8.7 15.3 0.14 11.9 10.8 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) FliD_N PF02465.18 KIY61254.1 - 1.4 9.7 5.4 0.73 10.6 3.1 1.8 2 0 0 2 2 1 0 Flagellar hook-associated protein 2 N-terminus TMPIT PF07851.13 KIY61254.1 - 1.5 8.0 7.3 0.75 9.0 4.9 1.6 2 0 0 2 2 2 0 TMPIT-like protein DUF4200 PF13863.6 KIY61254.1 - 1.5 9.2 16.3 2.9 8.3 13.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) ADIP PF11559.8 KIY61254.1 - 1.9 8.6 16.9 0.32 11.1 11.7 2.1 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding V_ATPase_I PF01496.19 KIY61254.1 - 2 6.3 5.6 2.1 6.2 5.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family LMBR1 PF04791.16 KIY61254.1 - 2 7.3 3.0 2.3 7.0 3.0 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF2730 PF10805.8 KIY61254.1 - 3.1 7.9 6.6 2.7 8.1 4.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2730) UPF0242 PF06785.11 KIY61254.1 - 3.2 7.8 10.9 1.7 8.7 8.6 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus MCU PF04678.13 KIY61254.1 - 3.3 7.8 5.8 1.1 9.4 3.1 1.6 2 0 0 2 2 2 0 Mitochondrial calcium uniporter TMF_DNA_bd PF12329.8 KIY61254.1 - 5.4 7.1 15.6 3 7.9 0.5 2.7 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding zf-CpG_bind_C PF12269.8 KIY61254.1 - 5.6 6.7 10.1 1.4 8.7 4.8 2.3 2 1 1 3 3 3 0 CpG binding protein zinc finger C terminal domain EMP24_GP25L PF01105.24 KIY61254.1 - 5.8 6.8 7.5 3.1 7.7 4.6 2.0 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF4446 PF14584.6 KIY61254.1 - 7.8 6.5 7.0 2.1 8.3 3.3 1.9 2 1 1 3 3 2 0 Protein of unknown function (DUF4446) CENP-H PF05837.12 KIY61254.1 - 9.7 6.6 13.6 2.6 8.5 8.1 2.5 1 1 2 3 3 3 0 Centromere protein H (CENP-H) Dimer_Tnp_hAT PF05699.14 KIY61256.1 - 7.2e-10 38.5 0.1 3e-09 36.5 0.0 2.2 2 1 0 2 2 2 1 hAT family C-terminal dimerisation region phage_tail_N PF08400.10 KIY61257.1 - 0.0092 16.0 0.0 0.021 14.8 0.0 1.6 1 0 0 1 1 1 1 Prophage tail fibre N-terminal Plavaka PF18759.1 KIY61258.1 - 1.4e-108 363.0 0.4 2e-108 362.5 0.4 1.2 1 0 0 1 1 1 1 Plavaka transposase Sigma70_ner PF04546.13 KIY61258.1 - 0.56 10.1 2.7 0.94 9.3 2.7 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region zf-C2H2 PF00096.26 KIY61258.1 - 4.3 8.0 6.0 0.48 11.0 0.3 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type YL1 PF05764.13 KIY61258.1 - 4.8 7.2 6.8 8.5 6.4 6.8 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Phage_XkdX PF09693.10 KIY61259.1 - 0.018 15.1 0.8 2.2 8.4 0.1 3.3 3 0 0 3 3 3 0 Phage uncharacterised protein (Phage_XkdX) T2SSE_N PF05157.15 KIY61264.1 - 0.14 12.4 0.0 0.23 11.7 0.0 1.3 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein E, N-terminal domain N2227 PF07942.12 KIY61266.1 - 6.4e-07 28.8 0.0 7e-07 28.7 0.0 1.0 1 0 0 1 1 1 1 N2227-like protein DUF4611 PF15387.6 KIY61268.1 - 1.1 9.5 0.0 1.1 9.5 0.0 4.6 3 2 2 5 5 5 0 Domain of unknown function (DUF4611) Macoilin PF09726.9 KIY61269.1 - 0.67 8.4 1.8 0.99 7.9 1.8 1.2 1 0 0 1 1 1 0 Macoilin family F-box-like PF12937.7 KIY61273.1 - 2.1e-10 40.3 0.6 2.1e-10 40.3 0.6 2.4 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 KIY61273.1 - 0.0034 17.2 0.5 0.038 13.9 0.3 2.9 2 0 0 2 2 2 1 F-box domain USP8_interact PF08941.10 KIY61273.1 - 0.021 14.6 0.6 1.7 8.4 0.0 2.2 2 0 0 2 2 2 0 USP8 interacting Leu_zip PF15294.6 KIY61274.1 - 5.3e-06 26.1 3.7 6.7e-06 25.8 3.7 1.2 1 0 0 1 1 1 1 Leucine zipper HMMR_N PF15905.5 KIY61274.1 - 0.00063 19.3 6.9 0.0012 18.4 6.9 1.3 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal TMF_TATA_bd PF12325.8 KIY61274.1 - 0.0032 17.7 9.0 0.2 11.9 4.2 2.2 1 1 1 2 2 2 2 TATA element modulatory factor 1 TATA binding DUF4763 PF15960.5 KIY61274.1 - 0.0038 16.6 3.7 0.0043 16.4 2.3 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4763) UPF0242 PF06785.11 KIY61274.1 - 0.0044 17.1 3.2 0.0052 16.9 3.2 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus Troponin PF00992.20 KIY61274.1 - 0.006 16.9 5.8 0.013 15.8 5.8 1.5 1 1 0 1 1 1 1 Troponin Tup_N PF08581.10 KIY61274.1 - 0.0064 16.8 6.2 0.098 13.0 2.1 2.3 1 1 1 2 2 2 1 Tup N-terminal DivIC PF04977.15 KIY61274.1 - 0.007 16.1 7.2 0.38 10.5 0.7 2.3 2 0 0 2 2 2 2 Septum formation initiator Fez1 PF06818.15 KIY61274.1 - 0.026 15.0 4.6 0.029 14.8 4.6 1.2 1 0 0 1 1 1 0 Fez1 FlxA PF14282.6 KIY61274.1 - 0.026 14.5 6.7 0.37 10.8 0.3 2.5 2 0 0 2 2 2 0 FlxA-like protein Seryl_tRNA_N PF02403.22 KIY61274.1 - 0.033 14.4 6.9 0.28 11.4 0.9 2.6 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain TPR_MLP1_2 PF07926.12 KIY61274.1 - 0.04 14.0 12.0 0.065 13.3 12.0 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein ZapB PF06005.12 KIY61274.1 - 0.057 13.9 0.9 0.057 13.9 0.9 2.2 2 0 0 2 2 2 0 Cell division protein ZapB DUF5320 PF17253.2 KIY61274.1 - 0.057 14.5 1.0 1.9 9.6 0.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5320) SlyX PF04102.12 KIY61274.1 - 0.1 13.2 9.1 3 8.5 1.8 2.7 1 1 1 2 2 2 0 SlyX DUF4201 PF13870.6 KIY61274.1 - 0.1 12.3 8.9 0.31 10.8 8.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) DUF724 PF05266.14 KIY61274.1 - 0.11 12.4 7.6 0.15 11.9 7.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Spc7 PF08317.11 KIY61274.1 - 0.11 11.3 8.3 0.14 11.0 8.3 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein GrpE PF01025.19 KIY61274.1 - 0.15 11.8 8.0 0.15 11.8 4.5 2.0 1 1 1 2 2 2 0 GrpE Golgin_A5 PF09787.9 KIY61274.1 - 0.23 10.9 9.3 0.32 10.4 9.3 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 LPP PF04728.13 KIY61274.1 - 0.34 11.3 7.3 1.9 8.9 1.2 2.5 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Csm1_N PF18504.1 KIY61274.1 - 0.35 11.2 8.1 2.1 8.7 1.2 2.4 2 0 0 2 2 2 0 Csm1 N-terminal domain ADIP PF11559.8 KIY61274.1 - 0.37 10.9 11.1 1 9.5 3.2 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Baculo_PEP_C PF04513.12 KIY61274.1 - 0.37 10.8 3.1 0.85 9.7 3.1 1.6 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF16 PF01519.16 KIY61274.1 - 0.61 10.6 7.2 0.57 10.7 1.8 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 TMF_DNA_bd PF12329.8 KIY61274.1 - 0.62 10.1 8.8 1.3 9.1 2.5 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Prominin PF05478.11 KIY61274.1 - 0.76 7.7 3.1 0.98 7.3 3.1 1.0 1 0 0 1 1 1 0 Prominin YgaB PF14182.6 KIY61274.1 - 0.89 10.0 7.1 1.2 9.6 3.9 2.1 1 1 1 2 2 2 0 YgaB-like protein DUF948 PF06103.11 KIY61274.1 - 0.92 9.8 4.9 22 5.4 4.6 2.2 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 KIY61274.1 - 0.97 9.5 4.7 5.8 7.0 4.7 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) XhlA PF10779.9 KIY61274.1 - 2.4 8.4 8.2 6.7 7.0 0.5 2.3 1 1 1 2 2 2 0 Haemolysin XhlA TMPIT PF07851.13 KIY61274.1 - 2.4 7.3 5.2 3 7.0 5.2 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF1003 PF06210.11 KIY61274.1 - 9.7 6.4 6.1 2.2 8.5 0.9 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1003) DA1-like PF12315.8 KIY61275.1 - 0.11 11.9 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein DA1 Sec23_trunk PF04811.15 KIY61276.1 - 1.5e-32 113.1 0.0 2.3e-32 112.5 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 KIY61276.1 - 1.5e-06 28.8 0.1 3.5e-06 27.7 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 KIY61276.1 - 2.7e-06 27.1 1.3 9.7e-05 22.1 1.3 2.9 1 1 0 1 1 1 1 Sec23/Sec24 helical domain Gelsolin PF00626.22 KIY61276.1 - 0.019 14.8 0.0 0.049 13.5 0.0 1.6 1 0 0 1 1 1 0 Gelsolin repeat LIN52 PF10044.9 KIY61279.1 - 0.17 12.6 0.0 0.45 11.3 0.0 1.7 1 0 0 1 1 1 0 Retinal tissue protein RNA_pol_A_bac PF01000.26 KIY61280.1 - 0.18 12.2 0.0 0.36 11.2 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb3/RpoA insert domain CENP-F_leu_zip PF10473.9 KIY61286.1 - 0.00082 19.4 11.8 0.00082 19.4 11.8 3.1 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 KIY61286.1 - 0.023 13.6 34.7 0.036 13.0 5.6 2.9 1 1 2 3 3 3 0 Spc7 kinetochore protein zf-C4H2 PF10146.9 KIY61286.1 - 0.025 14.9 23.9 0.087 13.1 7.4 2.2 1 1 1 2 2 2 0 Zinc finger-containing protein HAP1_N PF04849.13 KIY61286.1 - 0.078 12.2 32.2 0.21 10.8 21.1 2.3 2 0 0 2 2 2 0 HAP1 N-terminal conserved region ATG16 PF08614.11 KIY61286.1 - 0.11 12.7 41.3 0.17 12.1 7.9 2.7 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) HOOK PF05622.12 KIY61286.1 - 0.14 10.2 31.4 0.046 11.9 11.4 2.1 1 1 1 2 2 2 0 HOOK protein TRAF_BIRC3_bd PF16673.5 KIY61286.1 - 0.25 11.2 11.3 0.67 9.8 0.6 3.6 3 0 0 3 3 3 0 TNF receptor-associated factor BIRC3 binding domain DUF1664 PF07889.12 KIY61286.1 - 0.26 11.3 14.0 0.29 11.2 1.0 4.1 1 1 4 5 5 5 0 Protein of unknown function (DUF1664) AAA_13 PF13166.6 KIY61286.1 - 0.35 9.5 24.4 0.66 8.5 23.1 1.8 1 1 1 2 2 2 0 AAA domain Fez1 PF06818.15 KIY61286.1 - 0.42 11.0 35.0 0.87 10.0 15.5 3.1 1 1 2 3 3 3 0 Fez1 Filament PF00038.21 KIY61286.1 - 0.51 9.9 28.6 1.2 8.6 28.6 1.8 1 1 0 1 1 1 0 Intermediate filament protein Atg14 PF10186.9 KIY61286.1 - 0.52 9.4 28.8 0.43 9.6 12.2 2.4 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Tropomyosin PF00261.20 KIY61286.1 - 0.66 9.3 37.0 7.7 5.8 36.6 2.2 1 1 1 2 2 2 0 Tropomyosin DUF3037 PF11236.8 KIY61286.1 - 0.68 10.4 9.5 0.39 11.1 2.3 3.5 2 1 1 4 4 4 0 Protein of unknown function (DUF3037) DUF812 PF05667.11 KIY61286.1 - 0.87 8.4 28.9 2.1 7.1 19.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF812) BRE1 PF08647.11 KIY61286.1 - 1 9.5 25.7 0.28 11.3 6.2 3.2 1 1 2 3 3 3 0 BRE1 E3 ubiquitin ligase TMF_DNA_bd PF12329.8 KIY61286.1 - 1.3 9.1 35.2 0.53 10.3 1.3 4.4 2 1 2 4 4 4 0 TATA element modulatory factor 1 DNA binding Spectrin PF00435.21 KIY61286.1 - 1.3 9.5 24.9 5.6 7.5 11.8 3.9 1 1 2 3 3 3 0 Spectrin repeat HU-CCDC81_bac_2 PF18175.1 KIY61286.1 - 4.1 7.3 6.8 28 4.7 0.2 3.3 3 0 0 3 3 3 0 CCDC81-like prokaryotic HU domain 2 XhlA PF10779.9 KIY61286.1 - 6.6 7.0 21.1 5 7.4 0.5 4.1 4 0 0 4 4 3 0 Haemolysin XhlA UPF0242 PF06785.11 KIY61286.1 - 7.4 6.6 31.0 9.7 6.2 17.8 2.7 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Peptidase_C48 PF02902.19 KIY61288.1 - 2.3e-06 27.6 0.0 3.8e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain HD PF01966.22 KIY61293.1 - 3.1e-07 30.6 0.0 4.6e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 HD domain Queuosine_synth PF02547.15 KIY61293.1 - 0.089 11.9 0.0 0.11 11.5 0.0 1.1 1 0 0 1 1 1 0 Queuosine biosynthesis protein RasGEF PF00617.19 KIY61294.1 - 1.3e-47 162.2 0.0 2.4e-47 161.4 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KIY61294.1 - 3.3e-19 69.1 0.0 6.8e-19 68.1 0.0 1.5 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_2 PF07653.17 KIY61294.1 - 4e-13 48.8 0.0 8.5e-13 47.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KIY61294.1 - 3.5e-11 42.5 0.1 7.6e-11 41.5 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KIY61294.1 - 4.6e-11 42.4 0.0 1.2e-10 41.1 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain Focal_AT PF03623.13 KIY61294.1 - 0.18 11.8 1.0 2.4 8.2 0.4 2.6 2 1 0 2 2 2 0 Focal adhesion targeting region OPT PF03169.15 KIY61296.1 - 2.7e-10 39.5 0.4 3.5e-10 39.2 0.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein RRM_1 PF00076.22 KIY61300.1 - 3.7e-15 55.5 0.0 3.1e-08 33.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KIY61300.1 - 0.00031 20.5 0.0 0.17 11.7 0.0 2.3 2 0 0 2 2 2 2 Occluded RNA-recognition motif Nre_N PF04894.12 KIY61300.1 - 0.038 13.8 0.0 0.073 12.9 0.0 1.4 1 0 0 1 1 1 0 Archaeal Nre, N-terminal RNA_pol_Rpb6 PF01192.22 KIY61301.1 - 8.3e-16 57.7 0.1 1.3e-15 57.0 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb6 SIR2 PF02146.17 KIY61302.1 - 2.9e-34 118.5 0.0 1.3e-31 109.9 0.0 2.2 1 1 0 1 1 1 1 Sir2 family TPR_17 PF13431.6 KIY61303.1 - 1.6e-07 31.2 3.4 0.0012 19.1 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KIY61303.1 - 1.7e-05 24.6 33.5 0.012 15.7 1.1 6.7 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 KIY61303.1 - 3e-05 23.6 27.6 0.00083 19.1 1.7 5.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 KIY61303.1 - 3.4e-05 24.1 2.9 3.4e-05 24.1 2.9 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 KIY61303.1 - 7.9e-05 22.3 6.6 0.1 12.3 2.5 3.1 2 1 0 2 2 2 2 TPR repeat TPR_16 PF13432.6 KIY61303.1 - 0.00021 21.9 8.8 0.0061 17.2 2.0 3.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 KIY61303.1 - 0.00058 20.3 9.7 0.039 14.5 0.2 3.7 2 1 1 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KIY61303.1 - 0.012 15.8 4.5 0.067 13.4 2.7 2.5 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 KIY61303.1 - 0.045 14.0 18.6 0.67 10.3 1.1 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat Coatomer_E PF04733.14 KIY61303.1 - 0.12 11.7 0.9 0.17 11.3 0.3 1.6 2 0 0 2 2 2 0 Coatomer epsilon subunit TPR_14 PF13428.6 KIY61303.1 - 0.15 13.0 10.6 1.6 9.8 0.5 5.4 3 1 2 5 5 5 0 Tetratricopeptide repeat MIT PF04212.18 KIY61303.1 - 0.16 12.0 9.6 0.16 12.1 2.3 4.0 4 1 1 5 5 5 0 MIT (microtubule interacting and transport) domain TPR_7 PF13176.6 KIY61303.1 - 0.83 9.8 7.2 6.9 7.0 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Peptidase_C101 PF16218.5 KIY61304.1 - 0.0014 18.0 0.0 0.002 17.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C101 RGS PF00615.19 KIY61305.1 - 6.2e-06 26.5 0.0 1.7e-05 25.1 0.0 1.6 1 1 0 1 1 1 1 Regulator of G protein signaling domain DUF2892 PF11127.8 KIY61305.1 - 1.2 9.3 6.0 12 6.0 5.7 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2892) RGS PF00615.19 KIY61306.1 - 1.3e-05 25.5 0.0 3.4e-05 24.1 0.0 1.6 1 1 0 1 1 1 1 Regulator of G protein signaling domain Integrase_H2C2 PF17921.1 KIY61310.1 - 3.9e-15 55.7 0.3 5.5e-15 55.2 0.3 1.2 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 KIY61310.1 - 0.07 13.4 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 H2C2 zinc finger ATG11 PF10377.9 KIY61311.1 - 0.023 14.8 0.3 0.033 14.2 0.3 1.2 1 0 0 1 1 1 0 Autophagy-related protein 11 Cation_ATPase_C PF00689.21 KIY61313.1 - 3.1e-47 160.6 7.2 3.1e-47 160.6 7.2 2.2 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KIY61313.1 - 3.5e-40 137.5 1.3 3.5e-40 137.5 1.3 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 KIY61313.1 - 3e-19 68.9 0.1 6.4e-19 67.8 0.1 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KIY61313.1 - 2.9e-16 60.4 0.4 9.4e-16 58.7 0.4 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KIY61313.1 - 4.2e-08 32.8 0.0 1e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KIY61313.1 - 9.3e-05 22.3 0.3 0.0096 15.7 0.3 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase RVT_1 PF00078.27 KIY61316.1 - 0.085 12.4 0.1 0.92 9.0 0.1 2.1 1 1 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Ifi-6-16 PF06140.13 KIY61323.1 - 9.6e-06 25.4 13.7 1.6e-05 24.8 13.7 1.4 1 0 0 1 1 1 1 Interferon-induced 6-16 family Retrotrans_gag PF03732.17 KIY61326.1 - 1e-12 48.1 0.0 2.2e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein TP6A_N PF04406.14 KIY61329.1 - 3e-21 75.2 0.1 5.5e-21 74.3 0.1 1.5 1 0 0 1 1 1 1 Type IIB DNA topoisomerase AAA_16 PF13191.6 KIY61330.1 - 1.9e-11 44.7 0.1 9.6e-11 42.4 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KIY61330.1 - 2.8e-11 43.8 0.0 6.4e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KIY61330.1 - 5.8e-10 39.7 0.1 1.9e-09 38.0 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 KIY61330.1 - 1.3e-06 27.7 1.7 4.1e-05 22.8 0.1 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_7 PF12775.7 KIY61330.1 - 1.6e-05 24.5 0.0 3.3e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region NACHT PF05729.12 KIY61330.1 - 4.3e-05 23.5 0.1 0.00016 21.6 0.1 2.1 1 1 0 1 1 1 1 NACHT domain AAA_5 PF07728.14 KIY61330.1 - 0.00012 22.1 0.0 0.00035 20.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 KIY61330.1 - 0.00034 19.9 0.0 0.00075 18.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) TniB PF05621.11 KIY61330.1 - 0.00054 19.4 0.0 0.0012 18.2 0.0 1.5 1 0 0 1 1 1 1 Bacterial TniB protein AAA_19 PF13245.6 KIY61330.1 - 0.0011 19.3 0.0 0.003 17.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KIY61330.1 - 0.0015 18.5 0.0 0.0036 17.3 0.0 1.6 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea cobW PF02492.19 KIY61330.1 - 0.0019 17.8 0.0 0.022 14.3 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain KAP_NTPase PF07693.14 KIY61330.1 - 0.0021 17.4 1.1 0.019 14.3 0.0 2.3 2 1 1 3 3 3 1 KAP family P-loop domain DUF2075 PF09848.9 KIY61330.1 - 0.0034 16.7 0.0 0.0049 16.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.22 KIY61330.1 - 0.01 16.2 0.0 0.055 13.9 0.0 2.3 1 1 0 1 1 1 0 RNA helicase AFG1_ATPase PF03969.16 KIY61330.1 - 0.011 14.7 0.0 0.017 14.0 0.0 1.3 1 0 0 1 1 1 0 AFG1-like ATPase IstB_IS21 PF01695.17 KIY61330.1 - 0.019 14.7 0.0 0.6 9.8 0.0 2.3 1 1 0 1 1 1 0 IstB-like ATP binding protein Zeta_toxin PF06414.12 KIY61330.1 - 0.023 14.0 0.0 0.094 12.0 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin AAA_33 PF13671.6 KIY61330.1 - 0.024 14.8 0.0 0.079 13.1 0.0 1.9 2 0 0 2 2 1 0 AAA domain TsaE PF02367.17 KIY61330.1 - 0.025 14.6 0.0 0.067 13.2 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 KIY61330.1 - 0.025 14.0 0.0 0.049 13.0 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_11 PF13086.6 KIY61330.1 - 0.034 13.9 0.6 0.052 13.3 0.0 1.6 2 0 0 2 2 1 0 AAA domain NB-ARC PF00931.22 KIY61330.1 - 0.035 13.3 0.0 0.065 12.4 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain NTPase_1 PF03266.15 KIY61330.1 - 0.047 13.6 0.0 0.094 12.6 0.0 1.6 1 0 0 1 1 1 0 NTPase AAA_30 PF13604.6 KIY61330.1 - 0.07 12.8 0.0 0.23 11.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain TIP49 PF06068.13 KIY61330.1 - 0.081 12.1 0.0 0.18 11.0 0.0 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_14 PF13173.6 KIY61330.1 - 0.088 12.9 0.0 0.32 11.0 0.0 2.0 2 0 0 2 2 1 0 AAA domain Sigma54_activat PF00158.26 KIY61330.1 - 0.088 12.5 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.27 KIY61330.1 - 0.14 12.6 0.0 0.65 10.5 0.0 2.0 2 0 0 2 2 2 0 ABC transporter RuvB_N PF05496.12 KIY61330.1 - 0.26 11.0 1.0 4 7.2 0.0 2.8 2 1 1 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain PKI PF02827.16 KIY61331.1 - 0.17 12.1 0.1 0.4 10.9 0.1 1.5 1 0 0 1 1 1 0 cAMP-dependent protein kinase inhibitor F-box-like PF12937.7 KIY61334.1 - 7.5e-07 28.9 1.2 3e-06 27.0 1.2 2.1 1 1 0 1 1 1 1 F-box-like FAD_binding_3 PF01494.19 KIY61335.1 - 2e-76 257.5 0.0 2.7e-76 257.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KIY61335.1 - 0.00018 21.6 0.0 0.00045 20.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KIY61335.1 - 0.00086 18.6 0.0 0.0055 16.0 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KIY61335.1 - 0.0046 15.7 0.0 0.0074 15.0 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 KIY61335.1 - 0.0072 15.6 0.1 0.011 15.0 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KIY61335.1 - 0.0082 15.3 0.1 0.015 14.4 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 KIY61335.1 - 0.13 11.1 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Thi4 PF01946.17 KIY61335.1 - 0.17 11.1 0.0 0.28 10.4 0.0 1.2 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.22 KIY61335.1 - 0.24 10.4 0.0 0.34 9.9 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Oxidored_FMN PF00724.20 KIY61336.1 - 4.3e-101 338.6 0.0 4.9e-101 338.4 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Peptidase_S10 PF00450.22 KIY61341.1 - 5.4e-21 75.5 0.0 5.7e-21 75.4 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase NmrA PF05368.13 KIY61342.1 - 4.4e-19 69.0 0.0 5.5e-19 68.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 KIY61342.1 - 7.6e-05 23.0 0.0 0.00086 19.6 0.0 2.1 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 KIY61342.1 - 0.057 13.7 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain KR PF08659.10 KIY61342.1 - 0.13 12.2 0.1 0.41 10.5 0.0 1.7 2 0 0 2 2 2 0 KR domain NUDIX PF00293.28 KIY61343.1 - 4.7e-13 49.3 0.0 8.2e-13 48.5 0.0 1.5 1 1 0 1 1 1 1 NUDIX domain ANAPC4_WD40 PF12894.7 KIY61345.1 - 0.00071 19.8 0.0 0.87 9.9 0.0 3.3 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KIY61345.1 - 0.0048 17.7 0.0 0.36 11.8 0.0 3.2 3 0 0 3 3 3 1 WD domain, G-beta repeat Tup_N PF08581.10 KIY61346.1 - 0.0094 16.2 1.9 0.016 15.5 1.9 1.4 1 0 0 1 1 1 1 Tup N-terminal Med4 PF10018.9 KIY61346.1 - 0.013 15.1 2.7 0.053 13.2 1.9 2.0 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 UDPGP PF01704.18 KIY61346.1 - 0.054 12.1 0.1 0.062 11.9 0.1 1.1 1 0 0 1 1 1 0 UTP--glucose-1-phosphate uridylyltransferase Wbp11 PF09429.10 KIY61346.1 - 0.11 13.0 1.5 0.25 11.8 1.5 1.7 2 0 0 2 2 2 0 WW domain binding protein 11 Flg_hook PF02120.16 KIY61346.1 - 1.3 8.9 8.2 6.6 6.7 0.1 3.4 2 1 1 3 3 3 0 Flagellar hook-length control protein FliK DUF4618 PF15397.6 KIY61347.1 - 0.0064 16.0 0.1 0.012 15.0 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) MbeD_MobD PF04899.12 KIY61347.1 - 0.011 15.8 0.2 0.035 14.2 0.2 1.8 1 0 0 1 1 1 0 MbeD/MobD like DivIC PF04977.15 KIY61347.1 - 0.017 14.9 0.2 0.15 11.9 0.1 2.2 2 0 0 2 2 2 0 Septum formation initiator Ax_dynein_light PF10211.9 KIY61347.1 - 0.022 14.7 1.5 0.038 13.9 0.3 1.8 2 0 0 2 2 2 0 Axonemal dynein light chain BLOC1_2 PF10046.9 KIY61347.1 - 0.034 14.4 0.1 0.11 12.8 0.0 1.8 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF948 PF06103.11 KIY61347.1 - 0.036 14.3 1.1 0.12 12.7 1.1 1.9 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) SKA2 PF16740.5 KIY61347.1 - 0.049 13.4 0.3 0.42 10.4 0.2 2.2 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 COG6 PF06419.11 KIY61347.1 - 0.053 11.7 1.4 0.082 11.1 1.4 1.2 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 FlaC_arch PF05377.11 KIY61347.1 - 0.072 13.5 0.2 0.52 10.8 0.5 2.2 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Noelin-1 PF12308.8 KIY61347.1 - 0.088 12.8 0.1 0.33 10.9 0.1 1.9 1 1 1 2 2 2 0 Neurogenesis glycoprotein DUF327 PF03885.13 KIY61347.1 - 0.14 12.1 0.2 0.42 10.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF327) TolA_bind_tri PF16331.5 KIY61347.1 - 0.15 12.2 0.3 0.44 10.6 0.3 1.7 1 0 0 1 1 1 0 TolA binding protein trimerisation DUF1664 PF07889.12 KIY61347.1 - 0.15 12.1 1.3 0.29 11.2 0.7 1.8 2 0 0 2 2 1 0 Protein of unknown function (DUF1664) FUSC PF04632.12 KIY61347.1 - 0.17 10.4 6.4 0.26 9.8 6.4 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Cob_adeno_trans PF01923.18 KIY61347.1 - 0.21 11.7 1.4 0.42 10.7 0.2 1.9 1 1 1 2 2 2 0 Cobalamin adenosyltransferase Syntaxin-6_N PF09177.11 KIY61347.1 - 0.3 11.6 2.2 0.78 10.3 0.2 2.5 3 0 0 3 3 3 0 Syntaxin 6, N-terminal Hamartin PF04388.12 KIY61347.1 - 2.3 6.8 13.1 8.7 4.9 13.1 1.8 1 1 0 1 1 1 0 Hamartin protein RVT_1 PF00078.27 KIY61348.1 - 2e-10 40.6 0.0 2.3e-10 40.4 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) EGF_3 PF12947.7 KIY61350.1 - 0.0037 17.4 0.5 0.0065 16.6 0.0 1.6 2 0 0 2 2 2 1 EGF domain G-patch PF01585.23 KIY61353.1 - 7e-07 29.0 0.6 2.3e-06 27.4 0.6 2.0 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KIY61353.1 - 0.0089 16.1 0.3 0.0089 16.1 0.3 4.0 5 0 0 5 5 5 1 G-patch domain PGBA_C PF15437.6 KIY61353.1 - 0.034 14.5 13.8 0.034 14.5 13.8 2.6 2 0 0 2 2 2 0 Plasminogen-binding protein pgbA C-terminal DUF4813 PF16072.5 KIY61353.1 - 0.42 10.2 16.3 0.064 12.9 11.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4813) Rtf2 PF04641.12 KIY61353.1 - 0.58 9.5 13.1 0.71 9.2 0.8 2.2 2 0 0 2 2 2 0 Rtf2 RING-finger ELH PF02323.15 KIY61353.1 - 1.1 8.5 11.9 0.075 12.4 4.4 2.5 3 0 0 3 3 3 0 Egg-laying hormone precursor RR_TM4-6 PF06459.12 KIY61353.1 - 6.4 6.5 16.2 1.5 8.5 3.9 2.3 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 ADH_N PF08240.12 KIY61354.1 - 8.1e-22 77.2 0.2 2.5e-21 75.6 0.2 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KIY61354.1 - 2.2e-17 63.3 0.3 6.7e-17 61.7 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KIY61354.1 - 0.00013 21.4 0.1 0.00022 20.7 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KIY61354.1 - 0.0077 15.5 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 KIY61354.1 - 0.013 15.4 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.21 KIY61354.1 - 0.025 13.9 0.3 0.068 12.5 0.3 1.6 2 0 0 2 2 2 0 ThiF family NAD_binding_2 PF03446.15 KIY61354.1 - 0.038 14.1 0.0 0.069 13.3 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase PhoLip_ATPase_C PF16212.5 KIY61355.1 - 2.1e-79 266.8 25.6 4.7e-79 265.7 25.6 1.6 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KIY61355.1 - 5.7e-25 86.8 4.6 2e-24 85.0 4.6 2.0 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KIY61355.1 - 2.1e-12 47.8 0.5 3.1e-07 30.9 0.1 2.9 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KIY61355.1 - 3.9e-12 46.1 0.0 1.8e-11 44.0 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 KIY61355.1 - 5.5e-07 29.3 0.1 2.1e-06 27.4 0.0 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KIY61355.1 - 0.002 17.9 0.1 0.015 15.0 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DNA_III_psi PF03603.13 KIY61355.1 - 0.017 15.3 0.1 0.047 13.9 0.1 1.7 1 0 0 1 1 1 0 DNA polymerase III psi subunit PNP_UDP_1 PF01048.20 KIY61356.1 - 2.3e-18 66.3 0.0 4e-18 65.5 0.0 1.3 1 1 0 1 1 1 1 Phosphorylase superfamily Thioredoxin PF00085.20 KIY61357.1 - 2.4e-17 62.8 0.0 5.6e-17 61.6 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KIY61357.1 - 1.9e-05 25.1 0.0 4.2e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KIY61357.1 - 0.0007 19.9 0.0 0.62 10.4 0.0 2.4 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_9 PF14595.6 KIY61357.1 - 0.017 14.9 0.0 0.033 14.0 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin OST3_OST6 PF04756.13 KIY61357.1 - 0.25 10.6 0.0 0.34 10.2 0.0 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family zf-C3HC4_3 PF13920.6 KIY61358.1 - 4.8e-06 26.3 1.6 9e-06 25.5 1.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIY61358.1 - 5e-05 23.1 1.3 5e-05 23.1 1.3 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIY61358.1 - 8e-05 22.5 3.3 8.4e-05 22.4 2.1 1.7 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_4 PF14570.6 KIY61358.1 - 0.00064 19.5 2.5 0.00086 19.1 1.6 1.6 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.6 KIY61358.1 - 0.008 16.2 2.5 0.02 14.9 2.5 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KIY61358.1 - 0.0088 15.9 2.0 0.022 14.6 2.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KIY61358.1 - 0.0097 16.1 2.8 0.023 14.9 2.8 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KIY61358.1 - 0.018 15.3 1.7 0.041 14.2 1.7 1.6 1 0 0 1 1 1 0 Ring finger domain Prok-RING_4 PF14447.6 KIY61358.1 - 0.029 14.2 0.8 0.059 13.2 0.8 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 KIY61358.1 - 0.13 12.0 2.3 0.74 9.6 1.1 2.4 2 0 0 2 2 2 0 RING-like zinc finger F-box-like PF12937.7 KIY61359.1 - 4.4e-06 26.5 0.1 1.1e-05 25.2 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KIY61363.1 - 0.025 14.4 0.1 0.065 13.1 0.1 1.7 1 0 0 1 1 1 0 F-box-like F-box-like PF12937.7 KIY61365.1 - 0.00064 19.6 0.0 0.0028 17.5 0.0 2.2 1 0 0 1 1 1 1 F-box-like Plavaka PF18759.1 KIY61367.1 - 2e-113 378.9 0.4 2.6e-113 378.5 0.4 1.1 1 0 0 1 1 1 1 Plavaka transposase DUF1518 PF07469.12 KIY61368.1 - 0.021 15.2 3.7 0.089 13.2 3.7 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF1518) F-box-like PF12937.7 KIY61372.1 - 5.8e-09 35.7 0.2 2.3e-08 33.8 0.2 2.1 1 1 0 1 1 1 1 F-box-like F-box-like_2 PF13013.6 KIY61372.1 - 0.0076 16.2 0.5 0.027 14.4 0.1 2.2 2 0 0 2 2 2 1 F-box-like domain LRR_4 PF12799.7 KIY61372.1 - 0.069 13.6 2.0 34 5.0 0.1 4.7 3 3 1 4 4 4 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KIY61373.1 - 2.2e-08 33.8 2.7 6.7e-08 32.3 2.7 1.8 1 1 0 1 1 1 1 F-box-like F-box-like_2 PF13013.6 KIY61373.1 - 0.00056 19.9 0.0 0.00065 19.6 0.0 1.3 1 0 0 1 1 1 1 F-box-like domain FlaC_arch PF05377.11 KIY61373.1 - 0.019 15.4 0.1 0.028 14.8 0.1 1.3 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) TMF_TATA_bd PF12325.8 KIY61373.1 - 0.021 15.0 0.1 0.029 14.6 0.1 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding F-box PF00646.33 KIY61373.1 - 0.07 13.0 1.1 1.3 9.0 0.2 2.4 2 0 0 2 2 2 0 F-box domain TolA_bind_tri PF16331.5 KIY61373.1 - 0.076 13.1 0.1 0.12 12.5 0.1 1.3 1 0 0 1 1 1 0 TolA binding protein trimerisation PEP-utilisers_N PF05524.13 KIY61373.1 - 0.14 12.3 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal LPP PF04728.13 KIY61373.1 - 0.22 11.9 0.2 0.31 11.4 0.2 1.2 1 0 0 1 1 1 0 Lipoprotein leucine-zipper LRR_4 PF12799.7 KIY61374.1 - 0.024 15.1 9.7 5.8 7.5 0.3 5.4 5 2 2 7 7 7 0 Leucine Rich repeats (2 copies) Med9 PF07544.13 KIY61375.1 - 7.1e-05 22.8 0.0 0.0001 22.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 UPF0060 PF02694.15 KIY61377.1 - 0.076 13.2 0.2 0.076 13.2 0.2 2.9 2 1 1 3 3 3 0 Uncharacterised BCR, YnfA/UPF0060 family GST_N_3 PF13417.6 KIY61378.1 - 2.1e-12 47.3 0.0 3.4e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KIY61378.1 - 6.7e-10 39.2 0.0 1.1e-09 38.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KIY61378.1 - 7.4e-10 39.0 0.0 1.2e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KIY61378.1 - 9.7e-05 22.3 0.7 0.00015 21.7 0.1 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KIY61378.1 - 0.0023 18.5 0.0 0.0043 17.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KIY61378.1 - 0.0024 18.1 0.0 0.043 14.0 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 KIY61378.1 - 0.0047 17.1 0.0 0.0087 16.3 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin GST_C_3 PF14497.6 KIY61378.1 - 0.045 14.0 0.0 0.079 13.2 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain zf-MYND PF01753.18 KIY61379.1 - 0.0004 20.4 11.8 0.00085 19.4 11.8 1.6 1 0 0 1 1 1 1 MYND finger T3SS_needle_F PF09392.10 KIY61380.1 - 0.017 15.3 1.5 11 6.2 0.8 3.0 2 0 0 2 2 2 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF DUF273 PF03314.14 KIY61382.1 - 0.041 13.4 0.0 0.13 11.8 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function, DUF273 FGAR-AT_linker PF18072.1 KIY61382.1 - 0.069 13.7 0.0 0.19 12.3 0.0 1.7 1 0 0 1 1 1 0 Formylglycinamide ribonucleotide amidotransferase linker domain zf-RING_13 PF17977.1 KIY61385.1 - 0.17 12.1 0.2 0.17 12.1 0.2 1.7 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RRN7 PF11781.8 KIY61385.1 - 2.9 7.7 4.9 1.9 8.2 0.6 2.4 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Sad1_UNC PF07738.13 KIY61392.1 - 0.0041 17.1 0.0 0.0049 16.9 0.0 1.1 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal SAS4 PF15460.6 KIY61394.1 - 0.056 13.5 0.3 0.12 12.4 0.3 1.5 1 0 0 1 1 1 0 Something about silencing, SAS, complex subunit 4 HAMP PF00672.25 KIY61394.1 - 0.42 11.0 2.6 1.4e+02 2.9 0.0 3.8 4 0 0 4 4 4 0 HAMP domain G_glu_transpept PF01019.21 KIY61396.1 - 9e-159 529.5 0.0 1e-158 529.3 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Cellulase PF00150.18 KIY61398.1 - 9.9e-27 94.1 5.1 1.7e-26 93.3 5.1 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 KIY61398.1 - 2.1e-11 43.6 10.8 2.1e-11 43.6 10.8 2.6 2 0 0 2 2 2 1 Fungal cellulose binding domain Glyco_hydro_2_C PF02836.17 KIY61398.1 - 0.00012 21.3 0.0 0.00028 20.1 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_44 PF12891.7 KIY61398.1 - 0.0023 17.9 1.8 0.32 10.9 0.0 2.4 2 0 0 2 2 2 2 Glycoside hydrolase family 44 Glyco_hydro_1 PF00232.18 KIY61398.1 - 0.0031 16.0 0.2 0.0088 14.5 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 1 Lactamase_B PF00753.27 KIY61399.1 - 6.5e-16 58.9 0.3 1e-15 58.3 0.3 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KIY61399.1 - 2.3e-05 24.0 0.0 4.6e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Integrase_H2C2 PF17921.1 KIY61402.1 - 0.07 13.2 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Integrase zinc binding domain Cwf_Cwc_15 PF04889.12 KIY61406.1 - 0.46 10.2 9.7 0.34 10.6 6.2 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Ribosomal_60s PF00428.19 KIY61407.1 - 9.4 6.9 16.4 1.8 9.2 3.8 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein Zn_clus PF00172.18 KIY61410.1 - 1.2e-09 38.1 7.2 1.8e-09 37.5 7.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 KIY61411.1 - 0.033 14.3 7.6 0.37 11.0 1.8 2.3 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Phage_holin_5_2 PF16079.5 KIY61418.1 - 0.072 13.4 1.7 14 6.1 0.1 2.5 2 0 0 2 2 2 0 Phage holin family Hol44, in holin superfamily V FtsL PF04999.13 KIY61418.1 - 2.1 8.4 4.5 17 5.5 0.2 2.5 2 1 0 2 2 2 0 Cell division protein FtsL RVP_2 PF08284.11 KIY61419.1 - 1.3e-09 38.0 0.0 1.7e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 KIY61419.1 - 1.8e-09 38.0 0.0 3e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KIY61419.1 - 3e-08 34.2 0.0 5.6e-08 33.3 0.0 1.6 1 1 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 KIY61419.1 - 6e-06 26.1 0.0 8.6e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 KIY61419.1 - 0.0098 16.2 0.0 0.015 15.6 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Glycophorin_A PF01102.18 KIY61421.1 - 0.013 15.8 0.2 0.033 14.4 0.0 1.7 2 0 0 2 2 2 0 Glycophorin A WD40 PF00400.32 KIY61422.1 - 4.1e-14 52.8 15.0 0.011 16.6 0.0 7.1 7 0 0 7 7 7 4 WD domain, G-beta repeat NLE PF08154.12 KIY61422.1 - 1.4e-13 51.2 0.0 2.5e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.8 KIY61422.1 - 0.005 15.5 0.4 0.28 9.8 0.0 2.8 3 0 0 3 3 3 2 Nucleoporin Nup120/160 PQQ_3 PF13570.6 KIY61422.1 - 0.19 12.3 5.9 6.8 7.3 0.0 4.2 3 1 1 4 4 4 0 PQQ-like domain Seryl_tRNA_N PF02403.22 KIY61423.1 - 0.1 12.9 5.8 0.15 12.3 5.8 1.2 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain LMBR1 PF04791.16 KIY61423.1 - 0.32 9.8 0.3 0.36 9.7 0.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Spc24 PF08286.11 KIY61423.1 - 0.65 10.3 5.4 1.1 9.5 5.4 1.4 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 V_ATPase_I PF01496.19 KIY61423.1 - 2.2 6.1 4.7 2.9 5.7 4.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Pinin_SDK_memA PF04696.13 KIY61423.1 - 2.8 8.0 19.5 0.72 9.9 16.3 1.6 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region CorA PF01544.18 KIY61423.1 - 3 7.1 4.7 4.2 6.6 4.7 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF4407 PF14362.6 KIY61423.1 - 9 5.5 7.3 12 5.1 7.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) F-box-like PF12937.7 KIY61424.1 - 8.2e-08 32.0 4.6 1.1e-07 31.6 0.9 3.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIY61424.1 - 0.0023 17.8 0.7 0.0023 17.8 0.7 3.2 2 1 0 2 2 2 1 F-box domain L27_N PF09060.10 KIY61424.1 - 0.094 12.8 0.3 0.19 11.8 0.3 1.4 1 0 0 1 1 1 0 L27_N zf-CCHC PF00098.23 KIY61425.1 - 0.0021 18.1 3.2 0.0052 16.8 3.2 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 KIY61425.1 - 0.0091 15.8 3.0 0.017 14.9 3.0 1.4 1 0 0 1 1 1 1 Zinc knuckle Tox-HNH-HHH PF15637.6 KIY61425.1 - 0.03 14.5 1.4 0.073 13.2 1.4 1.6 1 0 0 1 1 1 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif gag-asp_proteas PF13975.6 KIY61425.1 - 0.051 14.1 0.0 0.29 11.7 0.0 2.2 3 0 0 3 3 3 0 gag-polyprotein putative aspartyl protease zf-CCHC_3 PF13917.6 KIY61425.1 - 0.11 12.5 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 Zinc knuckle Asp_protease_2 PF13650.6 KIY61425.1 - 0.22 12.2 0.0 0.82 10.4 0.0 2.0 2 1 0 2 2 2 0 Aspartyl protease DUF3364 PF11844.8 KIY61427.1 - 0.37 11.0 2.5 0.4 10.9 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3364) WH1 PF00568.23 KIY61429.1 - 1.3e-20 73.4 0.0 1.7e-20 73.0 0.0 1.2 1 0 0 1 1 1 1 WH1 domain PBD PF00786.28 KIY61429.1 - 6.7e-07 29.6 0.0 1.6e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 P21-Rho-binding domain F-box-like PF12937.7 KIY61430.1 - 2.7e-09 36.8 0.4 8.2e-09 35.2 0.1 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIY61430.1 - 0.088 12.7 2.7 1.9 8.5 2.7 2.6 1 1 0 1 1 1 0 F-box domain WD40 PF00400.32 KIY61431.1 - 8.4e-06 26.4 0.4 0.55 11.2 0.0 4.0 4 0 0 4 4 4 2 WD domain, G-beta repeat F-box-like PF12937.7 KIY61431.1 - 2.2e-05 24.3 5.5 7.7e-05 22.5 1.4 2.8 2 1 0 2 2 2 1 F-box-like ANAPC4_WD40 PF12894.7 KIY61431.1 - 0.019 15.2 0.2 6.9 7.0 0.0 3.0 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 KIY61431.1 - 0.024 14.5 2.1 0.086 12.8 0.1 2.5 2 0 0 2 2 2 0 F-box domain Pkinase PF00069.25 KIY61433.1 - 9.6e-51 172.7 0.0 1.1e-50 172.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY61433.1 - 4.5e-18 65.5 0.0 5.9e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY61433.1 - 5.1e-06 26.0 0.0 1.2e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 KIY61433.1 - 0.0032 16.6 0.0 0.0048 16.0 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.23 KIY61433.1 - 0.0036 17.2 0.0 0.0097 15.9 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KIY61433.1 - 0.0067 15.4 0.0 0.15 10.9 0.0 2.0 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 KIY61433.1 - 0.017 14.5 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KIY61433.1 - 0.024 13.4 0.0 0.039 12.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase COesterase PF00135.28 KIY61436.1 - 7.1e-59 200.0 0.3 8.8e-59 199.7 0.3 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KIY61436.1 - 2e-06 27.8 2.9 2.4e-05 24.3 2.9 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Lectin_leg-like PF03388.13 KIY61438.1 - 2.8e-59 200.3 0.2 3.8e-59 199.8 0.2 1.1 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.19 KIY61438.1 - 0.00098 18.7 0.0 0.19 11.2 0.0 2.2 2 0 0 2 2 2 2 Legume lectin domain GST_C PF00043.25 KIY61439.1 - 8.4e-17 61.2 0.0 1.3e-16 60.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KIY61439.1 - 8.6e-17 61.3 0.0 1.3e-16 60.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KIY61439.1 - 9.6e-14 51.6 0.0 2.1e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KIY61439.1 - 2.6e-10 40.5 0.0 4.6e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KIY61439.1 - 7.6e-09 35.5 0.0 1.2e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KIY61439.1 - 5.3e-07 29.8 0.0 9.8e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain COesterase PF00135.28 KIY61440.1 - 5.5e-87 292.8 0.0 6.2e-87 292.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KIY61440.1 - 1.3e-05 25.1 1.2 0.00024 21.0 1.1 2.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold p450 PF00067.22 KIY61441.1 - 2.1e-15 56.4 0.0 2.3e-15 56.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 eIF3g PF12353.8 KIY61442.1 - 0.16 12.4 0.4 0.42 11.0 0.4 1.7 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G zf-C3HC4_3 PF13920.6 KIY61448.1 - 2.7e-07 30.3 4.1 5e-07 29.5 4.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) KASH_CCD PF14662.6 KIY61448.1 - 9.1e-07 28.9 11.4 5.4e-06 26.4 11.3 1.8 1 1 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH zf-RING_5 PF14634.6 KIY61448.1 - 2.6e-06 27.3 6.8 5.1e-06 26.3 6.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KIY61448.1 - 1.5e-05 24.8 6.2 3.6e-05 23.6 6.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) NUDE_C PF04880.13 KIY61448.1 - 1.9e-05 25.2 0.3 2.5e-05 24.8 0.3 1.2 1 0 0 1 1 1 1 NUDE protein, C-terminal conserved region zf-RING_UBOX PF13445.6 KIY61448.1 - 2.5e-05 24.2 6.1 7.7e-05 22.6 6.1 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KIY61448.1 - 0.00033 20.7 7.2 0.00049 20.2 5.6 2.2 2 1 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KIY61448.1 - 0.00092 19.5 7.1 0.001 19.3 6.0 1.8 1 1 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KIY61448.1 - 0.0034 17.1 4.2 0.46 10.3 0.3 2.8 2 1 0 2 2 2 2 RING-like zinc finger CCDC144C PF14915.6 KIY61448.1 - 0.0036 16.5 6.9 0.0049 16.0 6.9 1.1 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region HAP1_N PF04849.13 KIY61448.1 - 0.0068 15.6 8.1 0.0089 15.3 8.1 1.1 1 0 0 1 1 1 1 HAP1 N-terminal conserved region OmpH PF03938.14 KIY61448.1 - 0.0069 16.7 5.4 0.0095 16.3 5.4 1.1 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) CENP-F_leu_zip PF10473.9 KIY61448.1 - 0.0092 16.0 10.9 0.015 15.3 10.9 1.3 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 zf-RING_4 PF14570.6 KIY61448.1 - 0.012 15.4 2.7 0.036 13.9 1.6 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain SPX PF03105.19 KIY61448.1 - 0.017 15.1 1.9 0.02 14.8 1.9 1.1 1 0 0 1 1 1 0 SPX domain zf-C3HC4_2 PF13923.6 KIY61448.1 - 0.022 14.6 5.6 0.022 14.6 5.6 2.1 2 1 0 2 2 1 0 Zinc finger, C3HC4 type (RING finger) LXG PF04740.12 KIY61448.1 - 0.023 14.4 5.0 0.032 14.0 5.0 1.1 1 0 0 1 1 1 0 LXG domain of WXG superfamily UPF0242 PF06785.11 KIY61448.1 - 0.024 14.7 4.9 0.037 14.1 4.9 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus KxDL PF10241.9 KIY61448.1 - 0.03 14.6 3.4 0.03 14.6 3.4 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein APG6_N PF17675.1 KIY61448.1 - 0.037 14.6 10.9 0.06 13.9 10.9 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region Dzip-like_N PF13815.6 KIY61448.1 - 0.041 13.8 2.5 0.041 13.8 2.5 1.8 1 1 0 1 1 1 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal DUF2968 PF11180.8 KIY61448.1 - 0.042 13.5 4.8 0.059 13.0 4.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) zf-RING_10 PF16685.5 KIY61448.1 - 0.042 14.0 7.2 0.12 12.5 5.5 2.3 2 1 0 2 2 2 0 zinc RING finger of MSL2 HSP70 PF00012.20 KIY61448.1 - 0.042 12.0 1.0 0.051 11.8 1.0 1.1 1 0 0 1 1 1 0 Hsp70 protein zf-C2H2_2 PF12756.7 KIY61448.1 - 0.054 13.8 0.2 0.054 13.8 0.2 2.1 2 1 1 3 3 2 0 C2H2 type zinc-finger (2 copies) GrpE PF01025.19 KIY61448.1 - 0.085 12.5 4.0 0.12 12.0 4.0 1.2 1 0 0 1 1 1 0 GrpE FapA PF03961.13 KIY61448.1 - 0.093 11.3 0.4 0.11 11.1 0.4 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A CENP-Q PF13094.6 KIY61448.1 - 0.15 12.3 8.8 0.25 11.5 8.9 1.4 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Peptidase_C98 PF15499.6 KIY61448.1 - 0.15 11.5 4.6 0.19 11.2 4.6 1.2 1 0 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Prok-RING_4 PF14447.6 KIY61448.1 - 0.17 11.7 8.3 0.34 10.8 8.3 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 T3SS_needle_E PF08988.10 KIY61448.1 - 0.18 12.0 3.6 0.42 10.8 3.6 1.5 1 0 0 1 1 1 0 Type III secretion system, cytoplasmic E component of needle ADIP PF11559.8 KIY61448.1 - 0.34 11.0 8.1 0.85 9.7 6.8 1.8 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Bcr-Abl_Oligo PF09036.10 KIY61448.1 - 0.38 10.8 3.4 6.1 6.9 1.4 2.4 1 1 1 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain zf-HC5HC2H_2 PF13832.6 KIY61448.1 - 0.43 10.8 6.2 1.4 9.1 6.0 2.0 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KIY61448.1 - 0.43 10.9 6.1 2.6 8.3 6.1 2.2 1 1 0 1 1 1 0 PHD-like zinc-binding domain TMPIT PF07851.13 KIY61448.1 - 0.58 9.3 3.4 0.84 8.8 3.4 1.1 1 0 0 1 1 1 0 TMPIT-like protein Prefoldin_2 PF01920.20 KIY61448.1 - 0.61 10.1 9.1 2.9 7.9 3.5 2.3 1 1 1 2 2 2 0 Prefoldin subunit DivIC PF04977.15 KIY61448.1 - 0.64 9.8 7.2 0.95 9.3 2.9 2.1 1 1 1 2 2 2 0 Septum formation initiator JIP_LZII PF16471.5 KIY61448.1 - 0.69 10.1 6.3 1.1 9.5 2.9 2.4 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II Tropomyosin_1 PF12718.7 KIY61448.1 - 0.79 9.9 10.3 2.3 8.4 0.8 2.1 1 1 1 2 2 2 0 Tropomyosin like Csm1_N PF18504.1 KIY61448.1 - 0.96 9.8 6.9 0.13 12.6 2.2 1.9 2 1 0 2 2 2 0 Csm1 N-terminal domain bZIP_1 PF00170.21 KIY61448.1 - 1.9 8.6 10.5 0.26 11.4 2.9 2.4 2 1 0 2 2 2 0 bZIP transcription factor Elf1 PF05129.13 KIY61448.1 - 3.3 7.8 7.0 27 4.9 2.9 2.9 2 1 1 3 3 2 0 Transcription elongation factor Elf1 like SlyX PF04102.12 KIY61448.1 - 6.4 7.5 7.2 62 4.3 0.1 2.7 2 1 0 2 2 2 0 SlyX Plavaka PF18759.1 KIY61449.1 - 8.6e-93 311.1 0.0 9.6e-82 274.8 0.0 2.2 1 1 1 2 2 2 2 Plavaka transposase Psb28 PF03912.14 KIY61450.1 - 0.098 12.9 0.2 0.19 12.0 0.2 1.4 1 0 0 1 1 1 0 Psb28 protein Pertus-S4-tox PF09275.10 KIY61452.1 - 0.037 14.3 0.2 0.091 13.0 0.1 1.6 1 1 0 2 2 2 0 Pertussis toxin S4 subunit JmjC PF02373.22 KIY61453.1 - 2.1e-13 50.7 0.0 4.2e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 KIY61453.1 - 0.016 14.9 0.0 0.046 13.5 0.0 1.7 1 0 0 1 1 1 0 Cupin domain DUF659 PF04937.15 KIY61455.1 - 0.02 14.8 0.0 0.028 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF 659) ADH_N_assoc PF13823.6 KIY61458.1 - 0.086 12.8 0.4 0.12 12.3 0.4 1.2 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated zf-C2H2_6 PF13912.6 KIY61459.1 - 0.0091 16.0 0.6 0.021 14.8 0.1 1.9 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2 PF00096.26 KIY61459.1 - 0.048 14.1 0.5 0.093 13.2 0.5 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIY61459.1 - 0.063 14.1 0.2 0.063 14.1 0.2 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger PGA2 PF07543.12 KIY61459.1 - 0.082 12.9 0.2 0.12 12.3 0.2 1.3 1 0 0 1 1 1 0 Protein trafficking PGA2 Plavaka PF18759.1 KIY61461.1 - 4e-91 305.6 0.1 4.5e-91 305.5 0.1 1.0 1 0 0 1 1 1 1 Plavaka transposase Plavaka PF18759.1 KIY61462.1 - 6.5e-14 51.9 0.0 9.3e-14 51.4 0.0 1.3 1 0 0 1 1 1 1 Plavaka transposase OrsD PF12013.8 KIY61463.1 - 0.001 19.5 1.2 0.001 19.5 1.2 2.6 3 0 0 3 3 3 1 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_4 PF13894.6 KIY61463.1 - 7.3 7.7 5.8 21 6.3 0.7 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger DUF2408 PF10303.9 KIY61464.1 - 0.012 16.1 0.2 0.025 15.2 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) LTXXQ PF07813.12 KIY61464.1 - 0.053 14.3 1.6 0.12 13.1 1.6 1.6 1 0 0 1 1 1 0 LTXXQ motif family protein Tet_JBP PF12851.7 KIY61466.1 - 0.18 11.2 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Oxygenase domain of the 2OGFeDO superfamily Imm64 PF15600.6 KIY61466.1 - 0.22 11.2 0.0 0.3 10.7 0.0 1.1 1 0 0 1 1 1 0 Immunity protein 64 zf-C3HC4 PF00097.25 KIY61467.1 - 2.5e-08 33.7 6.9 6.3e-08 32.4 6.9 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIY61467.1 - 1.4e-07 31.8 11.0 1.4e-07 31.8 11.0 1.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 KIY61467.1 - 1.7e-07 31.0 9.2 6.3e-07 29.2 9.2 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KIY61467.1 - 1.9e-06 27.8 6.0 1.9e-06 27.8 6.0 2.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KIY61467.1 - 6.5e-05 23.0 9.6 0.00024 21.2 9.6 2.0 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 KIY61467.1 - 0.00017 21.5 9.0 0.00063 19.7 9.0 2.0 1 1 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KIY61467.1 - 0.00022 21.0 10.1 0.00067 19.5 9.6 2.1 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 Torus PF16131.5 KIY61467.1 - 0.00042 21.0 0.0 0.00066 20.4 0.0 1.3 1 0 0 1 1 1 1 Torus domain zf-C3HC4_2 PF13923.6 KIY61467.1 - 0.00082 19.2 6.6 0.00082 19.2 6.6 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH PF00642.24 KIY61467.1 - 0.0067 16.3 0.1 0.0067 16.3 0.1 2.5 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KIY61467.1 - 0.013 15.5 1.4 0.027 14.5 0.2 2.3 2 0 0 2 2 2 0 Zinc finger domain zf-rbx1 PF12678.7 KIY61467.1 - 1.4 9.3 17.2 1.9 8.9 14.5 2.4 2 1 1 3 3 3 0 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KIY61467.1 - 6.1 7.0 11.1 1.2 9.2 7.1 1.9 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger TfuA PF07812.12 KIY61469.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 TfuA-like protein MerC PF03203.14 KIY61469.1 - 0.25 11.8 1.0 0.96 9.9 1.0 1.8 1 1 0 1 1 1 0 MerC mercury resistance protein Tudor_3 PF18115.1 KIY61471.1 - 0.00018 21.3 0.0 0.00042 20.1 0.0 1.6 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain DUF4537 PF15057.6 KIY61471.1 - 0.00046 20.2 0.0 0.001 19.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) PWWP PF00855.17 KIY61471.1 - 0.012 16.0 0.6 0.53 10.7 0.1 2.6 2 0 0 2 2 2 0 PWWP domain Plavaka PF18759.1 KIY61474.1 - 0.00087 18.6 0.0 0.0011 18.3 0.0 1.1 1 0 0 1 1 1 1 Plavaka transposase Isochorismatase PF00857.20 KIY61479.1 - 6.1e-29 101.4 0.1 1.4e-28 100.3 0.1 1.5 1 1 0 1 1 1 1 Isochorismatase family Glycos_transf_2 PF00535.26 KIY61479.1 - 0.11 12.3 0.1 0.24 11.2 0.1 1.5 2 0 0 2 2 2 0 Glycosyl transferase family 2 LRR_4 PF12799.7 KIY61481.1 - 0.0037 17.6 0.9 15 6.2 0.0 4.2 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) EHN PF06441.12 KIY61482.1 - 2.8e-34 117.8 0.3 4.5e-34 117.1 0.3 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KIY61482.1 - 1.3e-09 38.1 0.0 2.2e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIY61482.1 - 9.1e-07 29.7 1.7 9.1e-07 29.7 1.7 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family ADH_zinc_N PF00107.26 KIY61483.1 - 2.3e-21 76.1 0.0 3.7e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KIY61483.1 - 3.6e-14 52.6 0.0 6e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 KIY61483.1 - 5.9e-08 33.8 0.0 1.2e-07 32.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF2855 PF11017.8 KIY61483.1 - 0.022 14.5 0.0 0.034 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2855) AAA PF00004.29 KIY61485.1 - 1.5e-41 141.9 0.0 2.5e-41 141.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KIY61485.1 - 6.2e-12 45.3 0.0 1.2e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 KIY61485.1 - 5.6e-09 35.7 0.2 1.2e-08 34.6 0.2 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 KIY61485.1 - 2.9e-06 27.5 0.0 6.5e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KIY61485.1 - 2.8e-05 24.4 0.2 0.014 15.6 0.2 2.4 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 KIY61485.1 - 3.3e-05 23.2 0.0 6.4e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 KIY61485.1 - 0.00012 22.1 0.6 0.00047 20.2 0.1 2.3 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KIY61485.1 - 0.00019 21.9 0.2 0.0092 16.4 0.1 2.4 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KIY61485.1 - 0.0003 20.6 0.0 0.0018 18.0 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain ATPase PF06745.13 KIY61485.1 - 0.0025 17.2 0.0 0.091 12.1 0.0 2.2 1 1 1 2 2 2 1 KaiC AAA_14 PF13173.6 KIY61485.1 - 0.0061 16.6 0.1 0.019 15.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.11 KIY61485.1 - 0.0061 16.4 0.0 0.016 15.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KIY61485.1 - 0.0089 16.2 0.0 0.017 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain Prot_ATP_OB_N PF17758.1 KIY61485.1 - 0.013 15.2 0.1 0.06 13.0 0.0 2.2 2 0 0 2 2 2 0 Proteasomal ATPase OB N-terminal domain AAA_18 PF13238.6 KIY61485.1 - 0.02 15.4 0.0 0.042 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KIY61485.1 - 0.031 14.0 0.0 0.059 13.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Viral_helicase1 PF01443.18 KIY61485.1 - 0.031 14.0 0.0 0.053 13.3 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase TIP49 PF06068.13 KIY61485.1 - 0.042 13.0 0.0 0.069 12.3 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_28 PF13521.6 KIY61485.1 - 0.045 14.0 0.3 0.17 12.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KIY61485.1 - 0.059 13.0 0.5 2.9 7.4 0.1 2.5 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.6 KIY61485.1 - 0.089 12.5 0.2 0.28 10.9 0.2 1.8 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KIY61485.1 - 0.094 11.9 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Mg_chelatase PF01078.21 KIY61485.1 - 0.14 11.5 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 KIY61485.1 - 0.18 12.2 0.0 0.36 11.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase ATP-synt_ab PF00006.25 KIY61486.1 - 5.2e-63 212.5 0.0 8.7e-63 211.8 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 KIY61486.1 - 3.2e-22 78.8 1.0 1.1e-21 77.1 1.0 2.0 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain NB-ARC PF00931.22 KIY61486.1 - 0.0057 15.9 0.7 0.012 14.9 0.1 1.7 2 0 0 2 2 2 1 NB-ARC domain ATPase PF06745.13 KIY61486.1 - 0.015 14.7 0.4 0.065 12.6 0.2 2.0 2 0 0 2 2 2 0 KaiC RsgA_GTPase PF03193.16 KIY61486.1 - 0.031 14.2 0.5 0.065 13.1 0.1 1.6 2 0 0 2 2 2 0 RsgA GTPase NACHT PF05729.12 KIY61486.1 - 0.033 14.1 0.0 0.072 13.0 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.6 KIY61486.1 - 0.034 14.5 0.1 0.11 12.9 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 KIY61486.1 - 0.039 14.4 0.1 0.36 11.2 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 KIY61486.1 - 0.058 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_19 PF13245.6 KIY61486.1 - 0.08 13.3 0.6 0.3 11.4 0.1 2.0 2 0 0 2 2 2 0 AAA domain Helitron_like_N PF14214.6 KIY61489.1 - 7.4e-24 85.0 0.2 1e-23 84.5 0.2 1.2 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Vpu PF00558.19 KIY61489.1 - 0.0072 16.1 0.1 0.013 15.3 0.1 1.3 1 0 0 1 1 1 1 Vpu protein Spb1_C PF07780.12 KIY61489.1 - 0.026 14.2 1.2 0.032 13.9 0.5 1.4 2 0 0 2 2 2 0 Spb1 C-terminal domain Pkinase_Tyr PF07714.17 KIY61495.1 - 2.9e-13 49.7 0.1 1.1e-08 34.7 0.0 2.5 2 1 0 3 3 3 2 Protein tyrosine kinase Pkinase PF00069.25 KIY61495.1 - 3.5e-13 49.5 0.0 9.5e-12 44.8 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 KIY61495.1 - 0.0089 16.0 0.1 0.011 15.6 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KIY61495.1 - 0.035 13.7 0.0 0.062 12.9 0.0 1.3 1 0 0 1 1 1 0 RIO1 family DUF1192 PF06698.11 KIY61497.1 - 0.12 12.4 0.0 0.27 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) ERG4_ERG24 PF01222.17 KIY61498.1 - 2.1e-135 451.8 4.6 2.4e-135 451.7 4.6 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 KIY61498.1 - 1e-08 35.0 2.1 1e-08 35.0 2.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) ICMT PF04140.14 KIY61498.1 - 7e-05 23.2 0.0 0.00028 21.2 0.0 2.0 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KIY61498.1 - 0.0035 17.7 0.0 0.0035 17.7 0.0 2.7 4 0 0 4 4 4 1 Phospholipid methyltransferase Abhydrolase_1 PF00561.20 KIY61499.1 - 1.3e-17 64.3 0.0 1.1e-16 61.3 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIY61499.1 - 2.1e-08 35.0 0.0 3e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIY61499.1 - 1.2e-06 28.0 0.0 0.00054 19.3 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KIY61499.1 - 0.00017 21.1 0.0 0.00031 20.3 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 KIY61499.1 - 0.0016 18.1 0.0 0.0064 16.2 0.0 1.8 2 0 0 2 2 2 1 Putative esterase Ndr PF03096.14 KIY61499.1 - 0.021 13.5 0.0 0.025 13.3 0.0 1.2 1 0 0 1 1 1 0 Ndr family BAAT_C PF08840.11 KIY61499.1 - 0.037 14.0 0.0 0.21 11.5 0.0 1.9 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.16 KIY61499.1 - 0.2 11.4 0.0 11 5.7 0.0 2.6 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase GH131_N PF18271.1 KIY61500.1 - 4e-42 144.7 0.2 7.4e-42 143.8 0.2 1.4 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain CBM_1 PF00734.18 KIY61500.1 - 8.2e-13 48.1 11.7 1.9e-12 46.9 11.7 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain Polysacc_lyase PF14099.6 KIY61500.1 - 4e-06 26.8 0.3 6.3e-06 26.2 0.3 1.2 1 0 0 1 1 1 1 Polysaccharide lyase G-patch PF01585.23 KIY61501.1 - 1.5e-07 31.2 0.0 4e-06 26.6 0.0 2.3 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 KIY61501.1 - 0.041 14.0 0.2 0.78 9.9 0.0 2.6 2 0 0 2 2 2 0 G-patch domain FliG_M PF14841.6 KIY61502.1 - 0.018 15.2 0.1 0.45 10.8 0.0 2.7 3 0 0 3 3 3 0 FliG middle domain Lactamase_B_2 PF12706.7 KIY61502.1 - 0.14 11.6 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain EFG_IV PF03764.18 KIY61503.1 - 3e-35 120.6 0.0 2.3e-34 117.8 0.0 2.1 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 KIY61503.1 - 7.3e-23 80.4 0.0 1.3e-22 79.6 0.0 1.4 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 KIY61503.1 - 5.7e-05 23.1 0.0 0.00013 22.0 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II F-box-like PF12937.7 KIY61504.1 - 1.6e-07 31.1 0.6 5.2e-07 29.5 0.6 1.9 1 0 0 1 1 1 1 F-box-like SNF2_N PF00176.23 KIY61505.1 - 2.5e-41 141.5 0.0 5.2e-34 117.5 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 KIY61505.1 - 7.7e-09 35.9 0.0 1.6e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain GntR PF00392.21 KIY61505.1 - 0.0042 16.7 0.0 0.018 14.7 0.0 2.1 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family Pam17 PF08566.10 KIY61506.1 - 3.9e-52 176.4 0.0 4.7e-52 176.2 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 DUF5353 PF17304.2 KIY61506.1 - 0.0092 15.7 0.1 0.02 14.6 0.1 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5353) Bacteriocin_IIc PF10439.9 KIY61506.1 - 1.4 9.1 5.7 1.9 8.7 0.1 2.2 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide p450 PF00067.22 KIY61508.1 - 9.9e-71 238.8 0.0 1.8e-70 238.0 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Methyltr_RsmB-F PF01189.17 KIY61510.1 - 1.3e-41 142.5 0.0 2.1e-40 138.5 0.0 2.2 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 KIY61510.1 - 0.00066 19.8 0.0 0.0014 18.8 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF2431 PF10354.9 KIY61510.1 - 0.00082 19.7 0.0 0.0016 18.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) Kinetochor_Ybp2 PF08568.10 KIY61511.1 - 6.7e-20 71.1 2.5 7e-16 57.9 1.2 2.0 2 0 0 2 2 2 2 Uncharacterised protein family, YAP/Alf4/glomulin DapB_C PF05173.14 KIY61513.1 - 0.15 12.1 0.0 0.29 11.2 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, C-terminus ubiquitin PF00240.23 KIY61514.1 - 2.5e-09 36.8 0.0 9.3e-09 34.9 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin family RNase_H PF00075.24 KIY61516.1 - 7.5e-25 87.8 0.1 1.5e-24 86.8 0.1 1.5 1 0 0 1 1 1 1 RNase H ADH_N PF08240.12 KIY61517.1 - 8.8e-20 70.6 2.2 8.8e-20 70.6 2.2 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KIY61517.1 - 1.3e-14 54.3 1.1 6.3e-14 52.1 0.1 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KIY61517.1 - 0.00026 20.4 0.0 0.00042 19.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.6 KIY61517.1 - 0.00036 21.6 0.0 0.0006 20.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KIY61517.1 - 0.00054 19.3 0.0 0.00083 18.7 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 KIY61517.1 - 0.008 16.1 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.21 KIY61517.1 - 0.14 11.5 0.3 0.43 9.9 0.2 1.7 2 0 0 2 2 2 0 ThiF family GCP_N_terminal PF17681.1 KIY61518.1 - 5.7e-64 216.7 0.0 8.2e-64 216.1 0.0 1.2 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 KIY61518.1 - 2.8e-57 194.6 0.8 7e-57 193.2 0.1 1.9 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal CENP-B_dimeris PF09026.10 KIY61518.1 - 0.16 12.3 4.6 0.46 10.9 4.6 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Arm PF00514.23 KIY61519.1 - 4.5e-91 296.4 13.3 4.7e-13 48.7 0.1 8.2 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KIY61519.1 - 7.6e-22 77.4 1.2 1.8e-08 34.7 0.0 5.0 4 2 0 4 4 4 4 HEAT-like repeat IBB PF01749.20 KIY61519.1 - 3.3e-21 75.5 1.6 6.4e-21 74.6 1.6 1.5 1 0 0 1 1 1 1 Importin beta binding domain Arm_3 PF16186.5 KIY61519.1 - 2.5e-19 68.6 1.9 5.9e-19 67.4 1.9 1.6 1 0 0 1 1 1 1 Atypical Arm repeat HEAT_2 PF13646.6 KIY61519.1 - 1.4e-15 57.4 1.6 8e-06 26.2 0.0 5.1 2 1 2 5 5 5 4 HEAT repeats HEAT PF02985.22 KIY61519.1 - 2.2e-13 49.2 0.3 8.4e-05 22.5 0.0 6.2 6 0 0 6 6 6 3 HEAT repeat Arm_2 PF04826.13 KIY61519.1 - 2.1e-06 27.4 0.0 0.017 14.6 0.0 4.2 2 1 1 4 4 4 1 Armadillo-like Adaptin_N PF01602.20 KIY61519.1 - 6.4e-05 21.7 0.0 0.0014 17.3 0.0 2.3 1 1 1 2 2 2 1 Adaptin N terminal region RICTOR_V PF14668.6 KIY61519.1 - 0.00024 21.3 1.2 0.43 10.8 0.0 4.2 3 2 1 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 V-ATPase_H_C PF11698.8 KIY61519.1 - 0.00053 20.1 0.1 3.1 7.9 0.0 4.2 3 3 3 6 6 6 2 V-ATPase subunit H HEAT_PBS PF03130.16 KIY61519.1 - 0.0042 17.6 1.7 0.7 10.7 0.0 4.3 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat Mo25 PF08569.11 KIY61519.1 - 0.025 14.0 0.0 0.049 13.0 0.0 1.4 1 0 0 1 1 1 0 Mo25-like 2-Hacid_dh_C PF02826.19 KIY61520.1 - 6e-54 182.1 0.0 1.1e-53 181.2 0.0 1.4 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KIY61520.1 - 5.2e-10 39.1 0.0 6.9e-10 38.7 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KIY61520.1 - 0.046 13.9 0.0 0.15 12.3 0.0 1.8 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase zf-4CXXC_R1 PF10497.9 KIY61525.1 - 7e-07 29.4 10.8 1.5e-06 28.3 10.8 1.5 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Ribophorin_II PF05817.14 KIY61526.1 - 7.2e-31 107.4 0.0 8.6e-31 107.2 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II Sec20 PF03908.13 KIY61527.1 - 4.4e-17 61.8 4.8 2e-16 59.6 2.1 2.6 3 0 0 3 3 3 1 Sec20 Baculo_11_kDa PF06143.11 KIY61527.1 - 0.072 12.7 0.3 0.28 10.8 0.1 2.1 2 0 0 2 2 2 0 Baculovirus 11 kDa family SNARE PF05739.19 KIY61527.1 - 0.091 12.8 0.1 0.26 11.3 0.1 1.8 1 0 0 1 1 1 0 SNARE domain NPV_P10 PF05531.12 KIY61527.1 - 0.12 12.8 1.4 2.9 8.4 0.0 2.7 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Use1 PF09753.9 KIY61527.1 - 0.33 10.6 7.4 0.74 9.5 7.4 1.6 1 1 0 1 1 1 0 Membrane fusion protein Use1 Syntaxin-6_N PF09177.11 KIY61527.1 - 2.5 8.7 5.9 9.6 6.8 0.8 2.9 1 1 1 2 2 2 0 Syntaxin 6, N-terminal SprB PF13573.6 KIY61528.1 - 0.098 12.4 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 SprB repeat SprB PF13573.6 KIY61529.1 - 0.0027 17.4 0.0 0.0027 17.4 0.0 2.1 3 0 0 3 3 3 1 SprB repeat MFS_1 PF07690.16 KIY61531.1 - 5e-28 98.0 77.2 1.9e-21 76.4 39.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily F-box-like PF12937.7 KIY61532.1 - 0.0065 16.3 0.1 0.013 15.4 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY61532.1 - 0.0077 16.1 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 F-box domain Acetyltransf_3 PF13302.7 KIY61533.1 - 8.6e-18 65.3 0.0 1.2e-17 64.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIY61533.1 - 5.3e-07 29.9 0.0 1e-06 29.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 KIY61533.1 - 0.0018 18.0 0.0 0.0027 17.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIY61533.1 - 0.024 14.6 0.0 0.042 13.8 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein DUF2824 PF11039.8 KIY61533.1 - 0.092 12.7 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2824) FAD_binding_1 PF00667.20 KIY61534.1 - 6.5e-55 186.1 0.0 3.6e-54 183.7 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KIY61534.1 - 2e-27 96.1 0.9 5.6e-27 94.7 0.2 2.0 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 KIY61534.1 - 3.5e-21 75.9 0.0 1e-20 74.4 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 KIY61534.1 - 0.1 12.9 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 Flavodoxin domain SET PF00856.28 KIY61535.1 - 6.7e-09 36.3 0.0 9.1e-08 32.7 0.0 2.2 1 1 0 1 1 1 1 SET domain Band_7 PF01145.25 KIY61536.1 - 6.7e-15 55.6 0.6 1.2e-14 54.7 0.0 1.7 2 0 0 2 2 2 1 SPFH domain / Band 7 family DUF969 PF06149.12 KIY61536.1 - 0.058 12.8 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF969) FixG_C PF11614.8 KIY61536.1 - 0.084 13.1 0.1 2.6 8.3 0.0 2.6 2 1 1 3 3 3 0 IG-like fold at C-terminal of FixG, putative oxidoreductase Flot PF15975.5 KIY61536.1 - 6.3 7.0 12.0 1.2 9.3 7.2 2.1 1 1 1 2 2 2 0 Flotillin DUF1674 PF07896.12 KIY61537.1 - 1.9e-16 60.3 1.2 1.9e-16 60.3 1.2 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1674) ubiquitin PF00240.23 KIY61540.1 - 9.3e-07 28.5 0.1 1.7e-06 27.6 0.1 1.5 1 1 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.17 KIY61540.1 - 0.21 11.5 8.8 0.42 10.5 8.8 1.5 1 0 0 1 1 1 0 Ribosomal L40e family Chromo PF00385.24 KIY61541.1 - 0.14 12.1 0.0 0.33 10.9 0.0 1.7 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain PIP5K PF01504.18 KIY61543.1 - 0.047 12.9 0.8 0.092 12.0 0.8 1.5 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase AAA_assoc_2 PF16193.5 KIY61543.1 - 0.061 13.7 0.0 0.15 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA C-terminal domain NAM-associated PF14303.6 KIY61543.1 - 0.57 10.9 0.0 0.57 10.9 0.0 3.6 3 1 0 4 4 4 0 No apical meristem-associated C-terminal domain BUD22 PF09073.10 KIY61545.1 - 0.13 11.6 10.2 0.17 11.2 10.2 1.1 1 0 0 1 1 1 0 BUD22 YL1 PF05764.13 KIY61545.1 - 0.21 11.7 6.0 0.29 11.2 6.0 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Rrp44_CSD1 PF17216.3 KIY61545.1 - 0.31 10.8 1.9 0.57 9.9 1.9 1.4 1 0 0 1 1 1 0 Rrp44-like cold shock domain TFIIF_alpha PF05793.12 KIY61545.1 - 0.57 8.7 7.9 0.76 8.3 7.9 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Spt5_N PF11942.8 KIY61545.1 - 2.3 9.3 10.1 4.8 8.2 0.9 2.4 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal 2OG-FeII_Oxy_3 PF13640.6 KIY61546.1 - 0.047 14.6 0.0 0.058 14.3 0.0 1.3 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Plavaka PF18759.1 KIY61549.1 - 1.4e-09 37.7 0.0 4.2e-09 36.1 0.0 1.8 2 0 0 2 2 2 1 Plavaka transposase zf-C2H2_6 PF13912.6 KIY61549.1 - 0.064 13.3 0.2 0.2 11.7 0.1 1.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_4 PF13894.6 KIY61549.1 - 0.094 13.6 0.2 0.37 11.8 0.2 2.1 1 0 0 1 1 1 0 C2H2-type zinc finger Form-deh_trans PF09163.11 KIY61549.1 - 0.094 12.5 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Formate dehydrogenase N, transmembrane DNA_pol_phi PF04931.13 KIY61549.1 - 3.9 5.5 9.3 4.9 5.1 9.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi Retrotrans_gag PF03732.17 KIY61550.1 - 1e-05 25.7 3.2 1.9e-05 24.8 1.6 2.0 1 1 1 2 2 2 1 Retrotransposon gag protein Integrase_H2C2 PF17921.1 KIY61551.1 - 2.3e-07 30.8 0.3 3.8e-07 30.1 0.3 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain DEAD PF00270.29 KIY61551.1 - 0.22 11.3 0.0 0.25 11.1 0.0 1.2 1 0 0 1 1 1 0 DEAD/DEAH box helicase HEPN_AbiU2 PF18734.1 KIY61554.1 - 0.11 12.0 0.1 0.16 11.4 0.1 1.3 1 0 0 1 1 1 0 AbiU2 adh_short PF00106.25 KIY61555.1 - 0.00021 20.8 0.0 0.00066 19.2 0.0 1.7 1 1 1 2 2 2 1 short chain dehydrogenase AA_permease_2 PF13520.6 KIY61557.1 - 8.9e-11 41.3 10.7 7.3e-09 35.0 0.8 2.3 1 1 1 2 2 2 2 Amino acid permease Saf_2TM PF18303.1 KIY61557.1 - 0.14 11.8 4.6 7.3 6.2 3.9 2.9 2 1 1 3 3 3 0 SAVED-fused 2TM effector domain Egh16-like PF11327.8 KIY61558.1 - 6.8e-26 91.8 3.5 8.9e-26 91.4 3.5 1.2 1 0 0 1 1 1 1 Egh16-like virulence factor Retrotrans_gag PF03732.17 KIY61559.1 - 8.8e-06 25.9 2.6 1.8e-05 24.9 1.2 2.0 1 1 1 2 2 2 1 Retrotransposon gag protein Integrase_H2C2 PF17921.1 KIY61560.1 - 6.3e-08 32.6 0.2 1.1e-07 31.9 0.2 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain DEAD PF00270.29 KIY61560.1 - 0.12 12.1 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 DEAD/DEAH box helicase DUF4653 PF15546.6 KIY61563.1 - 0.017 14.8 0.6 0.017 14.8 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4653) Herpes_DNAp_acc PF04929.12 KIY61563.1 - 5 6.0 5.4 7 5.5 5.4 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Cauli_VI PF01693.16 KIY61567.1 - 2.1e-07 31.2 0.2 0.0045 17.3 0.0 2.9 2 1 0 2 2 2 2 Caulimovirus viroplasmin 3-alpha PF03475.14 KIY61569.1 - 0.2 11.6 1.6 0.24 11.3 0.3 1.8 2 0 0 2 2 2 0 3-alpha domain HSP70 PF00012.20 KIY61570.1 - 1.8e-06 26.4 0.0 1.9e-06 26.4 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein F-box-like PF12937.7 KIY61571.1 - 2.9e-05 23.8 0.7 8e-05 22.5 0.7 1.7 1 0 0 1 1 1 1 F-box-like Lipoprotein_X PF03305.13 KIY61572.1 - 0.023 14.5 0.0 0.024 14.4 0.0 1.0 1 0 0 1 1 1 0 Mycoplasma MG185/MG260 protein RVT_1 PF00078.27 KIY61573.1 - 0.0033 17.0 0.0 0.0097 15.4 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Terpene_synth_C PF03936.16 KIY61575.1 - 7.5e-11 41.9 0.0 1.2e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain ST7 PF04184.12 KIY61575.1 - 0.082 11.4 0.0 0.12 10.9 0.0 1.2 1 0 0 1 1 1 0 ST7 protein Fungal_trans PF04082.18 KIY61576.1 - 2.6e-19 69.3 1.0 4.4e-19 68.5 1.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY61576.1 - 1.3e-05 25.2 14.5 2.3e-05 24.4 14.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF5055 PF16478.5 KIY61576.1 - 0.063 13.5 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5055) DnaJ PF00226.31 KIY61577.1 - 8e-17 61.1 0.1 2.1e-16 59.8 0.1 1.8 1 0 0 1 1 1 1 DnaJ domain TPR_2 PF07719.17 KIY61577.1 - 3e-12 45.6 11.7 0.026 14.6 0.3 6.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 KIY61577.1 - 1e-11 45.2 18.7 3.2e-07 30.9 2.4 5.3 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.6 KIY61577.1 - 1.4e-11 44.7 11.9 0.00012 22.5 1.2 5.9 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.6 KIY61577.1 - 1e-10 41.6 5.8 0.0014 18.7 0.3 4.0 3 1 0 3 3 3 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KIY61577.1 - 7.6e-09 35.7 1.3 0.067 13.4 0.0 4.8 3 2 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 KIY61577.1 - 8.1e-09 34.9 9.6 0.002 17.8 0.2 5.5 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 KIY61577.1 - 3.4e-05 23.4 2.9 3.4e-05 23.4 2.9 3.5 3 0 0 3 3 3 1 TPR repeat TPR_7 PF13176.6 KIY61577.1 - 3.6e-05 23.5 9.7 3.8 7.8 0.2 5.7 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 KIY61577.1 - 6.2e-05 22.9 5.7 0.98 9.8 0.1 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 KIY61577.1 - 0.00024 21.6 19.7 0.27 12.2 0.4 6.8 5 3 3 8 8 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 KIY61577.1 - 0.0018 18.6 11.9 0.37 11.1 0.3 4.9 4 2 1 5 5 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 KIY61577.1 - 0.011 16.1 3.7 1.3 9.5 0.3 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KIY61577.1 - 0.011 16.3 11.4 9 7.2 0.1 6.7 8 0 0 8 8 5 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 KIY61577.1 - 0.013 16.0 2.0 9.6 6.7 0.1 3.2 3 0 0 3 3 3 0 Alkyl sulfatase dimerisation TPR_4 PF07721.14 KIY61577.1 - 0.025 15.2 7.1 27 5.8 0.1 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 KIY61577.1 - 0.027 14.5 0.6 0.3 11.1 0.0 2.6 2 1 0 2 2 2 0 Putative TPR-like repeat TPR_20 PF14561.6 KIY61577.1 - 0.032 14.6 2.5 6 7.3 0.1 3.6 3 1 0 3 3 2 0 Tetratricopeptide repeat Hypoth_Ymh PF09509.10 KIY61577.1 - 0.051 13.5 1.6 0.81 9.6 0.3 2.6 3 0 0 3 3 2 0 Protein of unknown function (Hypoth_ymh) BTAD PF03704.17 KIY61577.1 - 0.051 14.0 0.2 0.051 14.0 0.2 3.3 4 1 0 4 4 3 0 Bacterial transcriptional activator domain DUF5344 PF17279.2 KIY61577.1 - 0.078 13.6 0.2 0.23 12.1 0.2 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5344) TPR_10 PF13374.6 KIY61577.1 - 0.15 11.9 9.2 2.4 8.2 0.1 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat GRP PF07172.11 KIY61577.1 - 0.16 12.7 9.2 0.36 11.5 9.2 1.6 1 0 0 1 1 1 0 Glycine rich protein family T3SS_needle_E PF08988.10 KIY61577.1 - 0.2 11.8 2.5 9.5 6.5 0.2 3.8 3 0 0 3 3 3 0 Type III secretion system, cytoplasmic E component of needle TPR_21 PF09976.9 KIY61577.1 - 1.6 8.4 8.8 1.6 8.4 0.2 3.8 2 2 2 5 5 5 0 Tetratricopeptide repeat-like domain MIT PF04212.18 KIY61577.1 - 5 7.3 6.5 22 5.2 0.4 3.5 2 1 1 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_3 PF07720.12 KIY61577.1 - 5.7 7.0 5.8 8.7 6.5 0.4 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat Terpene_synth_C PF03936.16 KIY61578.1 - 9e-08 31.8 0.0 1.4e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain TRI5 PF06330.11 KIY61578.1 - 0.079 11.8 0.2 0.12 11.2 0.2 1.2 1 0 0 1 1 1 0 Trichodiene synthase (TRI5) Ran_BP1 PF00638.18 KIY61579.1 - 0.094 13.0 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 RanBP1 domain DUF1116 PF06545.11 KIY61584.1 - 0.068 12.6 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1116) Pkinase_fungal PF17667.1 KIY61585.1 - 4.3e-08 32.4 0.0 6e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_fungal PF17667.1 KIY61586.1 - 3.1e-05 22.9 0.0 4.3e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase UMPH-1 PF05822.12 KIY61586.1 - 0.0098 15.4 0.2 0.014 14.9 0.2 1.2 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) ANTH PF07651.16 KIY61586.1 - 0.065 12.2 0.0 0.094 11.7 0.0 1.2 1 0 0 1 1 1 0 ANTH domain PsaX PF08078.12 KIY61586.1 - 0.45 10.5 1.6 0.71 9.9 0.1 2.1 2 0 0 2 2 2 0 PsaX family CBFD_NFYB_HMF PF00808.23 KIY61588.1 - 6e-15 55.3 0.4 1.2e-14 54.3 0.4 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KIY61588.1 - 1.7e-09 38.1 2.1 1.7e-09 38.1 2.1 1.7 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KIY61588.1 - 0.0021 18.2 0.0 0.0033 17.5 0.0 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIIA PF03153.13 KIY61588.1 - 0.042 13.9 12.6 0.06 13.3 12.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pes-10 PF07149.11 KIY61588.1 - 2.4 7.1 7.1 3 6.8 7.1 1.2 1 0 0 1 1 1 0 Pes-10 Peptidase_S49_N PF08496.10 KIY61589.1 - 2 8.5 10.2 2 8.5 0.1 2.6 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Ras PF00071.22 KIY61590.1 - 1.5e-37 128.7 0.0 4.3e-36 124.0 0.1 2.1 2 0 0 2 2 2 1 Ras family Roc PF08477.13 KIY61590.1 - 5.4e-30 104.1 0.1 8.1e-30 103.5 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIY61590.1 - 2.6e-10 40.0 0.0 4.2e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KIY61590.1 - 8.7e-09 35.1 0.0 1.2e-08 34.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KIY61590.1 - 5.1e-06 26.6 0.1 7.9e-06 25.9 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KIY61590.1 - 0.0013 18.3 0.0 0.0073 15.9 0.0 2.2 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 KIY61590.1 - 0.01 16.1 0.0 0.023 14.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain SRPRB PF09439.10 KIY61590.1 - 0.018 14.5 0.0 0.027 13.9 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_24 PF13479.6 KIY61590.1 - 0.024 14.3 0.0 0.039 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KIY61590.1 - 0.04 14.3 0.0 0.084 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 KIY61590.1 - 0.042 14.0 0.0 0.083 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KIY61590.1 - 0.066 13.1 0.1 0.18 11.7 0.1 1.7 1 1 0 1 1 1 0 RsgA GTPase AAA_7 PF12775.7 KIY61590.1 - 0.14 11.7 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region PduV-EutP PF10662.9 KIY61590.1 - 0.23 11.2 0.0 0.39 10.5 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation adh_short PF00106.25 KIY61591.1 - 4.1e-20 72.1 0.1 9.3e-18 64.4 0.1 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KIY61591.1 - 5.3e-08 32.7 0.2 1.4e-07 31.3 0.3 1.7 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIY61591.1 - 0.00022 21.2 0.1 0.00044 20.2 0.1 1.4 1 0 0 1 1 1 1 KR domain DAHP_snth_FXD PF18152.1 KIY61591.1 - 0.035 13.9 0.0 0.1 12.4 0.0 1.8 2 0 0 2 2 2 0 DAHP synthase ferredoxin-like domain Polysacc_synt_2 PF02719.15 KIY61591.1 - 0.1 11.7 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 KIY61591.1 - 0.16 12.1 0.0 0.38 10.8 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pkinase_fungal PF17667.1 KIY61593.1 - 3.8e-10 39.1 0.0 5.4e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Imm7 PF15585.6 KIY61593.1 - 0.074 13.3 0.2 9.9 6.5 0.1 3.0 2 1 1 3 3 3 0 Immunity protein 7 Siva PF05458.12 KIY61593.1 - 0.2 11.3 0.0 0.35 10.5 0.0 1.3 1 0 0 1 1 1 0 Cd27 binding protein (Siva) Amidase PF01425.21 KIY61594.1 - 3.8e-10 39.3 0.0 6.8e-09 35.2 0.0 2.0 1 1 0 1 1 1 1 Amidase Peptidase_C12 PF01088.21 KIY61595.1 - 7.1e-52 176.2 0.0 1.6e-51 175.1 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 KIY61595.1 - 5.4e-12 45.4 0.2 1.1e-11 44.4 0.2 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases DUF2229 PF09989.9 KIY61595.1 - 0.099 12.3 0.1 0.19 11.3 0.1 1.5 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) DUF802 PF05650.11 KIY61595.1 - 0.23 12.0 3.7 0.33 11.4 2.8 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF802) Uds1 PF15456.6 KIY61595.1 - 0.38 10.9 6.8 0.12 12.5 0.6 2.1 2 0 0 2 2 2 0 Up-regulated During Septation HAD_2 PF13419.6 KIY61596.1 - 1.2e-17 64.6 0.0 1.6e-17 64.2 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KIY61596.1 - 2.5e-09 37.7 0.0 2.9e-07 31.0 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KIY61596.1 - 0.00017 21.6 0.0 0.00031 20.7 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Response_reg PF00072.24 KIY61596.1 - 0.013 15.6 0.0 0.045 13.9 0.0 1.8 2 0 0 2 2 2 0 Response regulator receiver domain HAD PF12710.7 KIY61596.1 - 0.088 13.2 0.1 0.12 12.8 0.1 1.4 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase NAD_Gly3P_dh_C PF07479.14 KIY61597.1 - 1.4e-38 132.4 0.0 2e-38 131.8 0.0 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 KIY61597.1 - 1.4e-37 129.1 0.0 2.2e-37 128.4 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.17 KIY61597.1 - 0.001 19.6 0.6 0.03 14.9 0.6 2.4 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Rossmann-like PF10727.9 KIY61597.1 - 0.0023 17.8 0.2 0.069 13.0 0.0 2.3 2 0 0 2 2 2 1 Rossmann-like domain Dsh_C PF12316.8 KIY61599.1 - 0.003 18.0 2.5 0.0037 17.7 2.5 1.2 1 0 0 1 1 1 1 Segment polarity protein dishevelled (Dsh) C terminal DUF1515 PF07439.11 KIY61599.1 - 0.029 14.4 0.2 0.045 13.8 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) PPV_E2_N PF00508.17 KIY61599.1 - 0.062 12.6 0.0 0.08 12.3 0.0 1.2 1 0 0 1 1 1 0 E2 (early) protein, N terminal Prefoldin PF02996.17 KIY61600.1 - 0.15 12.0 0.1 0.19 11.6 0.1 1.1 1 0 0 1 1 1 0 Prefoldin subunit zf-RING_2 PF13639.6 KIY61601.1 - 4.2e-12 46.2 6.7 6.9e-12 45.5 6.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KIY61601.1 - 3.2e-08 33.3 5.7 5.8e-08 32.5 5.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KIY61601.1 - 1.4e-07 31.7 3.7 2.8e-07 30.7 3.7 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KIY61601.1 - 5.2e-07 29.4 3.9 8.4e-07 28.8 3.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KIY61601.1 - 1.2e-06 28.3 1.7 1.9e-06 27.6 1.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KIY61601.1 - 1.5e-06 28.2 4.2 1.5e-06 28.1 2.8 1.8 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KIY61601.1 - 3.3e-06 27.0 1.8 5.1e-06 26.3 1.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 KIY61601.1 - 1.6e-05 24.5 1.7 2.5e-05 23.9 1.0 1.7 2 0 0 2 2 2 1 RING-like zinc finger Prok-RING_4 PF14447.6 KIY61601.1 - 0.0053 16.6 7.8 0.25 11.2 8.3 2.3 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KIY61601.1 - 0.0059 16.6 1.1 0.012 15.6 1.1 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KIY61601.1 - 0.023 14.3 3.7 0.04 13.6 3.7 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type RINGv PF12906.7 KIY61601.1 - 0.026 14.6 5.6 0.047 13.8 5.6 1.4 1 0 0 1 1 1 0 RING-variant domain PHD PF00628.29 KIY61601.1 - 0.089 12.7 2.9 0.15 11.9 2.9 1.4 1 0 0 1 1 1 0 PHD-finger zf-C3H2C3 PF17122.5 KIY61601.1 - 0.81 9.8 4.8 0.95 9.6 0.4 2.4 2 0 0 2 2 2 0 Zinc-finger zf-RING-like PF08746.11 KIY61601.1 - 0.86 10.0 2.3 1.5 9.2 2.3 1.4 1 0 0 1 1 1 0 RING-like domain zf-P11 PF03854.14 KIY61601.1 - 1.4 8.7 7.6 3.5 7.4 7.6 1.6 1 1 0 1 1 1 0 P-11 zinc finger FANCL_C PF11793.8 KIY61601.1 - 2.1 8.6 6.3 10 6.4 6.3 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain Collagen PF01391.18 KIY61605.1 - 1.8e-08 34.0 26.1 1.8e-08 34.0 26.1 2.3 1 1 1 2 2 2 1 Collagen triple helix repeat (20 copies) Collagen PF01391.18 KIY61609.1 - 2.6e-11 43.1 78.2 2.9e-09 36.5 32.1 2.4 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) zf-CCHC PF00098.23 KIY61609.1 - 0.00048 20.1 2.4 0.00099 19.1 2.4 1.6 1 0 0 1 1 1 1 Zinc knuckle gag-asp_proteas PF13975.6 KIY61609.1 - 0.02 15.4 0.1 0.057 14.0 0.0 1.8 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Peptidase_S32 PF05579.13 KIY61612.1 - 5.4e-05 22.5 0.3 8.4e-05 21.9 0.3 1.2 1 0 0 1 1 1 1 Equine arteritis virus serine endopeptidase S32 Peptidase_S64 PF08192.11 KIY61612.1 - 0.0073 14.9 0.0 0.016 13.7 0.0 1.4 2 0 0 2 2 2 1 Peptidase family S64 SMP PF04927.12 KIY61613.1 - 0.0018 18.7 11.7 0.076 13.5 0.3 3.7 4 0 0 4 4 4 2 Seed maturation protein DAZAP2 PF11029.8 KIY61613.1 - 0.19 12.7 4.6 3.3 8.6 0.1 2.4 2 0 0 2 2 2 0 DAZ associated protein 2 (DAZAP2) Glyco_hydro_28 PF00295.17 KIY61614.1 - 1.2e-34 119.9 6.3 1.6e-34 119.4 4.5 2.0 1 1 1 2 2 2 1 Glycosyl hydrolases family 28 B_lectin PF01453.24 KIY61618.1 - 0.01 16.4 0.0 0.031 14.8 0.0 1.9 2 0 0 2 2 2 0 D-mannose binding lectin StbA PF06406.11 KIY61618.1 - 0.097 11.9 0.1 0.14 11.4 0.1 1.1 1 0 0 1 1 1 0 StbA protein Bac_thur_toxin PF01338.18 KIY61619.1 - 2.5e-15 56.6 0.4 3.3e-15 56.2 0.4 1.2 1 0 0 1 1 1 1 Bacillus thuringiensis toxin VWA_CoxE PF05762.14 KIY61620.1 - 0.045 13.1 0.0 0.083 12.3 0.0 1.4 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein DTHCT PF08070.11 KIY61620.1 - 0.42 11.4 5.0 0.2 12.4 0.8 2.1 2 0 0 2 2 2 0 DTHCT (NUC029) region Pectate_lyase PF03211.13 KIY61621.1 - 1.9e-84 282.3 5.6 2.2e-84 282.1 5.6 1.0 1 0 0 1 1 1 1 Pectate lyase Ribosomal_L2_C PF03947.18 KIY61624.1 - 0.072 13.3 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 Ribosomal Proteins L2, C-terminal domain DGF-1_C PF11040.8 KIY61624.1 - 0.075 13.0 0.1 0.19 11.7 0.1 1.7 1 0 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus Plavaka PF18759.1 KIY61626.1 - 2.5e-85 286.6 1.6 1.2e-52 179.2 0.1 2.2 1 1 1 2 2 2 2 Plavaka transposase Rubredoxin_2 PF18073.1 KIY61627.1 - 0.052 13.3 6.9 3.5 7.4 2.5 2.7 2 0 0 2 2 2 0 Rubredoxin metal binding domain Stc1 PF12898.7 KIY61627.1 - 0.063 13.8 0.3 1.2 9.8 0.0 2.8 2 1 0 2 2 2 0 Stc1 domain DUF4451 PF14616.6 KIY61627.1 - 0.089 13.0 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4451) Ogr_Delta PF04606.12 KIY61627.1 - 0.11 12.5 1.7 0.29 11.1 1.7 1.7 1 0 0 1 1 1 0 Ogr/Delta-like zinc finger Pkinase PF00069.25 KIY61631.1 - 6e-69 232.3 0.0 7.1e-69 232.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY61631.1 - 3e-31 108.6 0.0 1.1e-30 106.8 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KIY61631.1 - 9.5e-05 21.5 0.0 0.00026 20.1 0.0 1.5 2 0 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 KIY61631.1 - 0.058 12.7 0.0 0.24 10.7 0.0 1.8 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.14 KIY61631.1 - 0.2 11.0 0.6 0.4 10.0 0.6 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NUDIX PF00293.28 KIY61632.1 - 1.8e-09 37.7 0.5 3.3e-09 36.9 0.5 1.4 1 1 0 1 1 1 1 NUDIX domain CS PF04969.16 KIY61642.1 - 4.2e-08 34.1 0.3 7.5e-08 33.3 0.3 1.4 1 0 0 1 1 1 1 CS domain PAC4 PF16093.5 KIY61643.1 - 1.8e-17 63.3 0.2 2.1e-17 63.1 0.2 1.1 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 SPX PF03105.19 KIY61645.1 - 3.2e-06 27.3 3.5 1.2e-05 25.4 0.9 2.6 3 0 0 3 3 3 1 SPX domain FGF-BP1 PF06473.12 KIY61647.1 - 4.8 6.9 8.3 0.36 10.6 2.7 1.7 1 1 1 2 2 2 0 FGF binding protein 1 (FGF-BP1) Dfp1_Him1_M PF08630.10 KIY61648.1 - 0.0028 17.9 0.0 0.0049 17.1 0.0 1.4 1 0 0 1 1 1 1 Dfp1/Him1, central region ESF1 PF18209.1 KIY61649.1 - 0.13 12.1 1.9 0.49 10.4 1.9 1.9 1 0 0 1 1 1 0 Embryo surrounding factor 1 KDZ PF18758.1 KIY61650.1 - 6.6e-70 235.2 0.0 1.1e-69 234.5 0.0 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase SIMPL PF04402.14 KIY61650.1 - 0.12 12.8 0.8 0.24 11.8 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF541) DUF3235 PF11574.8 KIY61650.1 - 0.23 12.4 1.5 1.4 9.8 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3235) YL1 PF05764.13 KIY61653.1 - 0.025 14.7 0.5 0.025 14.7 0.5 4.2 2 2 1 4 4 4 0 YL1 nuclear protein Zeta_toxin PF06414.12 KIY61654.1 - 0.044 13.1 0.0 0.061 12.6 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin MPDZ_u10 PF16667.5 KIY61654.1 - 0.29 12.1 3.0 0.63 11.0 3.0 1.6 1 0 0 1 1 1 0 Unstructured region 10 on multiple PDZ protein DAO PF01266.24 KIY61655.1 - 5e-08 32.9 0.0 6.3e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIY61655.1 - 2e-05 24.0 0.0 6.9e-05 22.2 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KIY61655.1 - 3.9e-05 24.0 0.0 5.1e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding NAD_binding_8 PF13450.6 KIY61655.1 - 0.0005 20.2 0.3 0.0012 19.0 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KIY61655.1 - 0.0023 18.4 0.1 0.0051 17.3 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KIY61655.1 - 0.0043 16.2 0.2 0.0076 15.4 0.1 1.4 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KIY61655.1 - 0.0053 16.0 0.0 0.0072 15.6 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KIY61655.1 - 0.0066 15.8 0.0 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 KIY61655.1 - 0.0095 15.2 0.0 0.021 14.1 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain FAD_binding_2 PF00890.24 KIY61655.1 - 0.031 13.4 0.0 0.043 12.9 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain ApbA PF02558.16 KIY61655.1 - 0.081 12.6 0.1 0.15 11.7 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 KIY61655.1 - 0.17 12.0 0.0 0.4 10.7 0.0 1.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_oxidored PF12831.7 KIY61655.1 - 0.18 11.1 0.2 0.46 9.8 0.1 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase TPR_2 PF07719.17 KIY61656.1 - 5.9e-11 41.6 18.7 0.0021 18.0 0.9 10.2 11 0 0 11 11 11 2 Tetratricopeptide repeat TPR_19 PF14559.6 KIY61656.1 - 7.5e-11 42.4 9.0 2.9 8.5 0.3 9.1 6 2 3 10 10 9 2 Tetratricopeptide repeat TPR_8 PF13181.6 KIY61656.1 - 5.7e-08 32.4 15.2 0.38 11.1 0.4 9.6 11 0 0 11 11 10 1 Tetratricopeptide repeat TPR_1 PF00515.28 KIY61656.1 - 9.9e-08 31.5 13.2 0.028 14.2 1.3 8.4 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_12 PF13424.6 KIY61656.1 - 2.8e-07 30.7 7.6 2.5 8.5 0.1 8.4 9 2 0 9 9 8 1 Tetratricopeptide repeat TPR_6 PF13174.6 KIY61656.1 - 2.7e-06 27.6 6.6 0.067 13.9 0.0 7.5 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_17 PF13431.6 KIY61656.1 - 4.5e-05 23.5 0.7 3.8 8.1 0.3 5.1 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 KIY61656.1 - 5.5e-05 22.8 9.5 9.9e-05 22.0 0.6 4.7 6 0 0 6 6 6 1 TPR repeat TPR_14 PF13428.6 KIY61656.1 - 6.5e-05 23.4 4.1 45 5.3 0.1 8.3 8 1 2 10 10 10 0 Tetratricopeptide repeat TPR_16 PF13432.6 KIY61656.1 - 0.00011 22.7 4.0 7.7 7.3 0.0 5.8 6 1 0 7 7 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 KIY61656.1 - 0.00086 19.2 7.2 32 4.9 0.0 8.2 10 0 0 10 10 9 0 Tetratricopeptide repeat TPR_20 PF14561.6 KIY61656.1 - 0.037 14.4 2.4 1.6 9.1 0.0 4.3 4 1 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KIY61656.1 - 0.16 12.2 12.1 0.69 10.2 0.2 5.9 6 3 2 8 8 8 0 Anaphase-promoting complex, cyclosome, subunit 3 Glyco_hydro_10 PF00331.20 KIY61657.1 - 3.2e-106 355.1 0.1 3.6e-106 354.9 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Glyco_hydro_10 PF00331.20 KIY61658.1 - 1.4e-102 343.1 0.2 1.6e-102 342.9 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 GYF_2 PF14237.6 KIY61658.1 - 0.084 12.7 0.1 0.2 11.5 0.1 1.6 1 0 0 1 1 1 0 GYF domain 2 PRELI PF04707.14 KIY61658.1 - 0.16 11.7 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 PRELI-like family DnaB_bind PF10410.9 KIY61658.1 - 0.23 11.6 0.7 0.55 10.5 0.1 1.9 3 0 0 3 3 3 0 DnaB-helicase binding domain of primase CybS PF05328.12 KIY61661.1 - 2.5e-43 146.9 0.0 3.2e-43 146.6 0.0 1.1 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit zf-MYND PF01753.18 KIY61662.1 - 9.9e-09 35.2 10.5 2.7e-08 33.8 10.5 1.8 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 KIY61662.1 - 0.02 15.0 3.8 0.039 14.0 3.8 1.4 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 PPO1_DWL PF12142.8 KIY61662.1 - 0.1 12.4 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 Polyphenol oxidase middle domain zf-C6H2 PF15801.5 KIY61662.1 - 0.29 11.5 8.6 0.59 10.5 8.6 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding TFIIF_alpha PF05793.12 KIY61663.1 - 2 6.9 5.9 2.5 6.6 5.9 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Ndc1_Nup PF09531.10 KIY61665.1 - 3.4 6.2 9.2 3.9 6.1 9.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Plavaka PF18759.1 KIY61666.1 - 1.2e-113 379.7 0.1 2.2e-113 378.8 0.1 1.5 1 0 0 1 1 1 1 Plavaka transposase GCIP PF13324.6 KIY61668.1 - 0.05 13.2 8.6 0.092 12.3 8.6 1.3 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Nucleo_P87 PF07267.11 KIY61668.1 - 0.061 12.2 5.2 0.1 11.4 5.2 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 PTR PF12789.7 KIY61668.1 - 0.12 12.5 0.2 0.24 11.5 0.2 1.4 1 0 0 1 1 1 0 Phage tail repeat like CNDH2_C PF16858.5 KIY61668.1 - 1 9.2 9.8 0.08 12.8 3.5 2.0 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term NOA36 PF06524.12 KIY61668.1 - 2.1 7.6 10.8 3.4 6.9 10.8 1.3 1 0 0 1 1 1 0 NOA36 protein DUF3042 PF11240.8 KIY61668.1 - 2.2 8.4 6.3 0.21 11.7 1.2 2.0 2 0 0 2 2 1 0 Protein of unknown function (DUF3042) DNA_pol_phi PF04931.13 KIY61668.1 - 2.3 6.2 13.2 3.4 5.7 13.2 1.2 1 0 0 1 1 1 0 DNA polymerase phi RXT2_N PF08595.11 KIY61668.1 - 2.5 8.1 8.4 5.8 6.9 8.4 1.6 1 0 0 1 1 1 0 RXT2-like, N-terminal MSP1_C PF07462.11 KIY61668.1 - 3.5 6.2 5.3 6.2 5.4 5.3 1.3 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus PPP4R2 PF09184.11 KIY61668.1 - 5.3 6.5 17.9 11 5.5 17.9 1.4 1 0 0 1 1 1 0 PPP4R2 TFB6 PF17110.5 KIY61668.1 - 7.8 6.2 7.5 16 5.2 7.5 1.4 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH CDC45 PF02724.14 KIY61668.1 - 8.3 4.6 11.1 14 3.9 11.1 1.2 1 0 0 1 1 1 0 CDC45-like protein Kinesin PF00225.23 KIY61669.1 - 1.2e-98 330.1 0.0 1.6e-55 188.4 0.0 3.0 2 0 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 KIY61669.1 - 5.5e-23 81.6 0.0 2.3e-22 79.6 0.0 2.1 2 0 0 2 2 2 1 Microtubule binding TolA_bind_tri PF16331.5 KIY61669.1 - 0.0021 18.1 7.8 0.0021 18.1 7.8 11.6 8 4 4 12 12 12 2 TolA binding protein trimerisation FAM184 PF15665.5 KIY61669.1 - 0.0026 17.5 21.4 0.0026 17.5 21.4 10.4 5 2 4 9 9 9 2 Family with sequence similarity 184, A and B FliJ PF02050.16 KIY61669.1 - 0.011 15.9 2.0 0.011 15.9 2.0 12.5 7 4 7 14 14 14 0 Flagellar FliJ protein VASP_tetra PF08776.11 KIY61669.1 - 0.12 12.0 5.9 7.8 6.2 0.1 4.3 3 0 0 3 3 3 0 VASP tetramerisation domain AA_kinase PF00696.28 KIY61670.1 - 3.6e-38 131.5 0.0 1.4e-37 129.6 0.0 1.9 1 1 0 1 1 1 1 Amino acid kinase family ACT PF01842.25 KIY61670.1 - 6.9e-12 44.9 0.7 8e-07 28.7 0.1 2.7 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.6 KIY61670.1 - 4.8e-11 42.3 1.2 3e-08 33.3 0.3 3.0 3 0 0 3 3 3 2 ACT domain Arginase PF00491.21 KIY61671.1 - 2.1e-76 257.1 0.1 2.5e-76 256.9 0.1 1.0 1 0 0 1 1 1 1 Arginase family Catalase PF00199.19 KIY61672.1 - 1.2e-186 620.4 0.2 1.5e-186 620.1 0.2 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 KIY61672.1 - 1.2e-16 60.6 0.0 3.5e-16 59.2 0.0 1.8 1 0 0 1 1 1 1 Catalase-related immune-responsive Trypsin_2 PF13365.6 KIY61676.1 - 0.11 13.4 0.5 0.41 11.5 0.0 2.3 2 0 0 2 2 2 0 Trypsin-like peptidase domain Podoplanin PF05808.11 KIY61677.1 - 2.1e-05 24.7 0.8 2.1e-05 24.7 0.8 2.0 2 0 0 2 2 2 1 Podoplanin MGC-24 PF05283.11 KIY61677.1 - 0.00034 21.1 2.9 0.00034 21.1 2.9 2.5 3 0 0 3 3 3 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin TMEM154 PF15102.6 KIY61677.1 - 0.00082 19.3 0.1 0.0021 17.9 0.1 1.7 1 0 0 1 1 1 1 TMEM154 protein family Rax2 PF12768.7 KIY61677.1 - 0.021 14.3 0.0 0.035 13.6 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Adeno_E3_CR2 PF02439.15 KIY61677.1 - 0.057 13.2 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 VEGFR-2_TMD PF17988.1 KIY61677.1 - 0.29 10.6 1.8 0.46 10.0 1.8 1.3 1 0 0 1 1 1 0 VEGFR-2 Transmembrane domain UQ_con PF00179.26 KIY61678.1 - 1.9e-50 170.2 0.0 2.2e-50 170.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KIY61678.1 - 0.00011 21.9 0.0 0.00015 21.5 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KIY61678.1 - 0.15 12.4 0.0 0.18 12.1 0.0 1.4 1 1 0 1 1 1 0 RWD domain Stealth_CR2 PF11380.8 KIY61679.1 - 2.9e-16 59.6 0.6 3.3e-09 36.9 0.0 3.9 3 1 1 4 4 4 2 Stealth protein CR2, conserved region 2 Stealth_CR3 PF17102.5 KIY61679.1 - 4.2e-07 29.8 2.5 8.5e-07 28.8 0.4 2.2 2 0 0 2 2 2 1 Stealth protein CR3, conserved region 3 Stealth_CR1 PF17101.5 KIY61679.1 - 5.7e-05 22.8 0.2 0.00011 21.8 0.2 1.5 1 0 0 1 1 1 1 Stealth protein CR1, conserved region 1 SDA1 PF05285.12 KIY61679.1 - 0.0024 17.4 12.9 0.0044 16.5 12.9 1.4 1 0 0 1 1 1 1 SDA1 CDC45 PF02724.14 KIY61679.1 - 0.0029 16.0 10.1 0.004 15.5 10.1 1.1 1 0 0 1 1 1 1 CDC45-like protein Rrn6 PF10214.9 KIY61679.1 - 0.038 12.5 0.3 0.059 11.9 0.3 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Nop14 PF04147.12 KIY61679.1 - 0.039 12.2 17.1 0.054 11.7 17.1 1.1 1 0 0 1 1 1 0 Nop14-like family Sigma70_ner PF04546.13 KIY61679.1 - 0.09 12.7 12.0 0.15 11.9 12.0 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region PTPRCAP PF15713.5 KIY61679.1 - 0.11 12.8 11.8 0.23 11.7 11.8 1.5 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Mpp10 PF04006.12 KIY61679.1 - 0.16 10.4 15.7 0.22 9.9 15.7 1.1 1 0 0 1 1 1 0 Mpp10 protein RRN3 PF05327.11 KIY61679.1 - 0.3 9.6 12.2 0.45 9.0 12.2 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DNA_pol_phi PF04931.13 KIY61679.1 - 0.36 8.9 25.5 0.55 8.3 25.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi Tim54 PF11711.8 KIY61679.1 - 0.38 9.5 5.1 0.61 8.8 5.1 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Pox_Ag35 PF03286.14 KIY61679.1 - 0.6 9.9 10.7 1.1 9.0 10.7 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein RPA43_OB PF17875.1 KIY61679.1 - 1.1 9.9 4.5 2.6 8.7 4.5 1.6 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I PPP4R2 PF09184.11 KIY61679.1 - 1.1 8.8 18.1 1.9 8.0 18.1 1.3 1 0 0 1 1 1 0 PPP4R2 YL1 PF05764.13 KIY61679.1 - 1.7 8.7 17.9 3 7.9 17.9 1.3 1 0 0 1 1 1 0 YL1 nuclear protein CobT PF06213.12 KIY61679.1 - 1.8 7.9 19.7 3.4 7.0 19.7 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Vfa1 PF08432.10 KIY61679.1 - 2.1 8.7 9.4 3.9 7.8 9.4 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 FAM176 PF14851.6 KIY61679.1 - 2.1 8.0 13.1 5.5 6.6 13.1 1.6 1 0 0 1 1 1 0 FAM176 family DUF913 PF06025.12 KIY61679.1 - 2.6 6.9 3.5 4.1 6.3 3.5 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) eIF-3c_N PF05470.12 KIY61679.1 - 2.9 6.1 8.6 4.1 5.6 8.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus NOA36 PF06524.12 KIY61679.1 - 6.3 6.0 23.5 9.5 5.4 23.5 1.2 1 0 0 1 1 1 0 NOA36 protein PI3K_1B_p101 PF10486.9 KIY61679.1 - 6.4 4.4 6.2 8.8 4.0 6.2 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit CwsA PF10814.8 KIY61683.1 - 0.018 15.2 1.2 0.028 14.6 1.2 1.4 1 0 0 1 1 1 0 Cell wall synthesis protein CwsA Plavaka PF18759.1 KIY61685.1 - 4.1e-114 381.2 0.1 5.9e-114 380.6 0.1 1.3 1 0 0 1 1 1 1 Plavaka transposase LSM14 PF12701.7 KIY61687.1 - 4.4e-24 84.4 0.0 7.7e-24 83.6 0.0 1.4 1 0 0 1 1 1 1 Scd6-like Sm domain SM-ATX PF14438.6 KIY61687.1 - 0.00042 20.4 0.0 0.00082 19.5 0.0 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain FDF PF09532.10 KIY61687.1 - 0.0019 19.0 6.9 0.0031 18.3 1.1 2.7 2 1 1 3 3 3 1 FDF domain BAG6 PF12057.8 KIY61687.1 - 0.06 13.0 0.0 0.092 12.4 0.0 1.3 1 0 0 1 1 1 0 BCL2-associated athanogene 6 RTA1 PF04479.13 KIY61688.1 - 2.2e-49 167.9 7.0 2.6e-49 167.6 7.0 1.0 1 0 0 1 1 1 1 RTA1 like protein F-box PF00646.33 KIY61689.1 - 0.03 14.2 0.0 0.03 14.2 0.0 2.7 3 0 0 3 3 3 0 F-box domain IIGP PF05049.13 KIY61690.1 - 1.9e-25 89.7 1.1 7.7e-25 87.7 0.0 2.1 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) MMR_HSR1 PF01926.23 KIY61690.1 - 3.1e-07 30.5 0.0 1.1e-06 28.6 0.0 2.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 KIY61690.1 - 0.00029 21.3 0.1 0.00029 21.3 0.1 2.9 2 1 0 2 2 1 1 ABC transporter RsgA_GTPase PF03193.16 KIY61690.1 - 0.00036 20.5 0.3 0.00036 20.5 0.3 2.8 3 2 1 4 4 4 1 RsgA GTPase AAA_29 PF13555.6 KIY61690.1 - 0.0046 16.7 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Roc PF08477.13 KIY61690.1 - 0.005 17.0 0.3 0.026 14.8 0.0 2.3 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_21 PF13304.6 KIY61690.1 - 0.0091 15.8 0.4 0.049 13.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system TFIIA PF03153.13 KIY61690.1 - 0.033 14.2 20.8 0.05 13.6 20.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AAA_23 PF13476.6 KIY61690.1 - 0.046 14.2 0.0 0.046 14.2 0.0 3.4 2 1 0 2 2 1 0 AAA domain AAA_28 PF13521.6 KIY61690.1 - 0.05 13.8 0.4 0.05 13.8 0.4 3.3 2 1 0 2 2 1 0 AAA domain Dynamin_N PF00350.23 KIY61690.1 - 0.12 12.5 0.0 0.12 12.5 0.0 3.3 2 1 0 2 2 1 0 Dynamin family AAA_16 PF13191.6 KIY61690.1 - 0.24 11.8 0.0 0.24 11.8 0.0 3.2 2 1 0 2 2 1 0 AAA ATPase domain SMC_N PF02463.19 KIY61690.1 - 0.38 10.2 0.0 0.38 10.2 0.0 2.1 2 1 1 3 3 3 0 RecF/RecN/SMC N terminal domain DUF572 PF04502.13 KIY61690.1 - 0.45 10.1 23.7 0.81 9.2 23.7 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF87 PF01935.17 KIY61690.1 - 0.54 10.3 0.0 0.54 10.3 0.0 2.7 3 0 0 3 3 1 0 Helicase HerA, central domain DUF3987 PF13148.6 KIY61690.1 - 0.86 8.5 0.0 0.86 8.5 0.0 3.4 1 1 2 3 3 1 0 Protein of unknown function (DUF3987) Borrelia_P83 PF05262.11 KIY61690.1 - 6.5 5.1 35.1 0.26 9.8 29.3 1.6 2 0 0 2 2 2 0 Borrelia P83/100 protein ATP_bind_1 PF03029.17 KIY61690.1 - 7 6.4 7.1 21 4.8 1.9 3.0 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein TFIIF_alpha PF05793.12 KIY61692.1 - 0.35 9.4 4.0 0.46 9.0 4.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF3498 PF12004.8 KIY61692.1 - 5.3 6.1 10.2 7.2 5.7 10.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3498) Aldo_ket_red PF00248.21 KIY61694.1 - 1.8e-71 240.8 0.0 2e-71 240.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MEF2_binding PF09047.10 KIY61694.1 - 0.3 10.9 0.6 9.8 6.1 0.0 2.4 2 0 0 2 2 2 0 MEF2 binding F-box-like PF12937.7 KIY61695.1 - 1.3e-08 34.6 0.3 1.3e-08 34.6 0.3 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIY61695.1 - 2e-07 30.7 1.1 6.5e-07 29.1 1.1 2.0 1 0 0 1 1 1 1 F-box domain Helicase_C PF00271.31 KIY61696.1 - 1.8e-17 63.7 0.0 8.8e-17 61.5 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KIY61696.1 - 3.1e-16 59.6 0.0 6.8e-16 58.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 KIY61696.1 - 4.5e-09 36.9 1.0 1.4e-08 35.3 1.0 1.9 1 0 0 1 1 1 1 RecQ zinc-binding AA_permease_2 PF13520.6 KIY61698.1 - 1.2e-71 241.8 40.2 1.4e-71 241.5 40.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KIY61698.1 - 2.1e-21 76.1 33.1 2.9e-21 75.6 33.1 1.2 1 0 0 1 1 1 1 Amino acid permease Aa_trans PF01490.18 KIY61698.1 - 3e-07 29.5 12.3 3e-07 29.5 12.3 2.0 2 0 0 2 2 2 1 Transmembrane amino acid transporter protein 2OG-FeII_Oxy_3 PF13640.6 KIY61703.1 - 0.095 13.6 0.0 0.19 12.6 0.0 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily zf-RING_5 PF14634.6 KIY61704.1 - 0.0022 17.9 2.6 0.0048 16.8 2.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KIY61704.1 - 0.0037 17.6 3.5 0.0037 17.6 3.5 1.8 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 KIY61704.1 - 0.006 16.6 1.5 0.011 15.7 1.5 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KIY61704.1 - 0.0084 16.0 1.4 0.017 15.0 1.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 KIY61704.1 - 0.022 14.6 5.6 0.059 13.2 5.6 1.8 1 1 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4_2 PF13923.6 KIY61704.1 - 0.031 14.1 2.0 0.088 12.7 2.0 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 KIY61704.1 - 0.061 13.5 4.7 0.087 13.0 4.1 1.6 1 1 0 1 1 1 0 zinc RING finger of MSL2 Zn_ribbon_17 PF17120.5 KIY61704.1 - 0.19 11.4 3.4 0.48 10.1 3.4 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 KIY61704.1 - 0.28 11.1 5.4 0.65 9.9 5.4 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Cyclin_N PF00134.23 KIY61705.1 - 2.3e-41 140.5 1.0 4.9e-41 139.4 0.4 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KIY61705.1 - 1.8e-24 86.1 0.1 3e-24 85.4 0.1 1.4 1 0 0 1 1 1 1 Cyclin, C-terminal domain tRNA-synt_1 PF00133.22 KIY61706.1 - 2.3e-156 521.5 0.0 3.1e-156 521.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KIY61706.1 - 1.5e-21 77.0 0.0 3e-21 76.0 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KIY61706.1 - 2.1e-19 69.6 5.2 2.9e-15 55.9 0.0 3.7 4 0 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 KIY61706.1 - 0.001 18.5 0.0 0.7 9.2 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain zf-FPG_IleRS PF06827.14 KIY61706.1 - 0.069 13.0 6.7 0.15 12.0 6.7 1.6 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS tRNA-synt_1_2 PF13603.6 KIY61706.1 - 0.19 11.2 0.0 0.34 10.4 0.0 1.3 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 Ndc1_Nup PF09531.10 KIY61707.1 - 8.8 4.9 6.5 9.3 4.8 6.5 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Zn_Tnp_IS91 PF14319.6 KIY61708.1 - 0.9 9.6 11.2 3.1 7.9 6.2 2.1 1 1 1 2 2 2 0 Transposase zinc-binding domain DUF4413 PF14372.6 KIY61710.1 - 0.0085 16.4 0.1 0.025 15.0 0.0 1.9 2 1 0 2 2 2 1 Domain of unknown function (DUF4413) Glyco_hydro_16 PF00722.21 KIY61712.1 - 1.6e-22 79.8 0.3 2.3e-22 79.3 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF1080 PF06439.11 KIY61712.1 - 0.0071 16.5 0.1 0.014 15.5 0.1 1.3 1 1 0 1 1 1 1 Domain of Unknown Function (DUF1080) COX7C PF02935.16 KIY61713.1 - 5.1e-13 49.1 3.4 5.5e-13 49.0 3.4 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc Zn_clus PF00172.18 KIY61714.1 - 2.2e-14 53.3 25.9 2.3e-07 30.8 8.3 2.3 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain FMO-like PF00743.19 KIY61715.1 - 3.9e-34 118.0 0.0 1.7e-27 96.0 0.0 2.3 1 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KIY61715.1 - 7.6e-13 48.4 0.1 7.7e-11 41.8 0.1 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KIY61715.1 - 8.1e-11 41.7 0.0 3.2e-10 39.7 0.0 2.1 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KIY61715.1 - 3.2e-07 30.5 0.0 0.011 15.7 0.0 3.6 4 0 0 4 4 4 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KIY61715.1 - 0.0007 19.8 0.0 0.0077 16.4 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KIY61715.1 - 0.092 11.9 0.1 1.3 8.1 0.0 2.6 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 KIY61715.1 - 0.11 11.7 0.4 10 5.3 0.2 2.4 3 0 0 3 3 3 0 FAD binding domain HI0933_like PF03486.14 KIY61715.1 - 0.16 10.7 0.1 2.7 6.6 0.0 2.3 3 0 0 3 3 3 0 HI0933-like protein Thi4 PF01946.17 KIY61715.1 - 0.16 11.1 0.5 5.1 6.3 0.1 2.1 2 0 0 2 2 2 0 Thi4 family Bromo_TP PF07524.13 KIY61716.1 - 9.2e-09 35.2 0.0 1.5e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated TAF8_C PF10406.9 KIY61716.1 - 1.8e-05 25.2 5.2 0.00017 22.0 5.2 2.6 1 1 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term Tetraspanin PF00335.20 KIY61717.1 - 1.3e-06 28.3 3.5 1.3e-06 28.3 3.5 1.9 1 1 0 2 2 2 1 Tetraspanin family DUF1282 PF06930.12 KIY61717.1 - 0.0018 18.0 0.0 0.0078 16.0 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1282) Pkinase PF00069.25 KIY61718.1 - 3.9e-66 223.1 0.0 5.1e-66 222.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY61718.1 - 4.6e-30 104.8 0.0 6.3e-30 104.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 KIY61718.1 - 8.7e-15 55.2 3.9 1.3e-14 54.6 0.6 2.9 2 1 0 2 2 2 1 Protein kinase C terminal domain C2 PF00168.30 KIY61718.1 - 1.4e-08 35.0 0.1 0.00019 21.7 0.0 2.4 2 0 0 2 2 2 2 C2 domain Kinase-like PF14531.6 KIY61718.1 - 1.3e-07 31.3 0.1 6.4e-06 25.7 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KIY61718.1 - 2.8e-07 29.8 0.0 4.2e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 KIY61718.1 - 0.0023 17.6 0.2 0.31 10.6 0.1 2.3 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KIY61718.1 - 0.0087 16.0 0.2 0.015 15.3 0.2 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family PsiA PF06952.11 KIY61719.1 - 0.049 12.9 1.1 0.08 12.2 1.1 1.3 1 0 0 1 1 1 0 PsiA protein Nop14 PF04147.12 KIY61719.1 - 0.24 9.5 32.1 0.39 8.9 32.1 1.3 1 0 0 1 1 1 0 Nop14-like family TBK1_ULD PF18396.1 KIY61720.1 - 0.073 13.0 0.0 0.3 11.0 0.0 2.0 1 1 1 2 2 2 0 TANK binding kinase 1 ubiquitin-like domain Arrestin_N PF00339.29 KIY61721.1 - 4e-09 36.7 0.0 1.2e-08 35.1 0.0 1.8 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KIY61721.1 - 8.3e-09 36.0 0.0 0.0019 18.7 0.0 2.5 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.7 KIY61721.1 - 0.14 11.8 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Arrestin_N terminal like Pyridoxal_deC PF00282.19 KIY61722.1 - 6.1e-18 64.7 0.0 9.2e-18 64.1 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KIY61722.1 - 1.6e-11 43.8 0.0 3.7e-07 29.4 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KIY61722.1 - 4.3e-05 23.0 0.2 8.5e-05 22.0 0.2 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family PHB_depo_C PF06850.11 KIY61722.1 - 0.099 12.1 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 PHB de-polymerase C-terminus TBK1_ULD PF18396.1 KIY61723.1 - 0.04 13.8 0.1 0.19 11.7 0.0 2.0 1 1 1 2 2 2 0 TANK binding kinase 1 ubiquitin-like domain ABC2_membrane PF01061.24 KIY61725.1 - 5.8e-85 284.0 58.7 1.3e-45 155.4 26.0 2.9 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 KIY61725.1 - 3.4e-38 131.2 0.0 1e-17 64.9 0.0 2.7 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KIY61725.1 - 3.8e-35 119.7 1.6 2e-30 104.5 0.0 3.3 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.6 KIY61725.1 - 2.4e-17 63.3 0.1 1e-16 61.3 0.0 2.1 2 0 0 2 2 2 1 ABC-transporter N-terminal AAA_25 PF13481.6 KIY61725.1 - 1.1e-07 31.7 0.5 1.2e-06 28.3 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 KIY61725.1 - 7.1e-07 29.8 0.3 0.0029 18.0 0.1 2.4 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KIY61725.1 - 3.1e-05 23.9 0.1 0.0022 17.9 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_21 PF13304.6 KIY61725.1 - 0.00011 22.1 0.1 0.4 10.4 0.1 3.2 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 KIY61725.1 - 0.00025 20.3 12.3 0.00025 20.3 12.3 2.7 2 1 1 3 3 3 1 ABC-2 family transporter protein AAA_33 PF13671.6 KIY61725.1 - 0.00038 20.6 0.2 0.45 10.7 0.1 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KIY61725.1 - 0.00045 19.9 0.5 0.013 15.3 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 KIY61725.1 - 0.00052 20.3 0.1 1.4 9.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KIY61725.1 - 0.00062 20.3 0.1 0.029 14.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KIY61725.1 - 0.0035 17.6 0.1 0.19 12.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 KIY61725.1 - 0.0037 16.7 0.0 0.26 10.7 0.0 2.9 3 1 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 KIY61725.1 - 0.0052 16.5 0.4 0.84 9.3 0.1 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KIY61725.1 - 0.0053 16.7 1.1 2.3 8.1 0.3 2.6 2 0 0 2 2 2 2 NACHT domain cobW PF02492.19 KIY61725.1 - 0.036 13.7 1.5 3.2 7.3 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 KIY61725.1 - 0.04 14.4 0.0 11 6.4 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 KIY61725.1 - 0.064 13.7 0.2 2.9 8.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KIY61725.1 - 0.13 12.0 0.1 13 5.4 0.0 2.6 3 0 0 3 3 2 0 AAA domain AAA_23 PF13476.6 KIY61725.1 - 0.13 12.7 0.0 0.35 11.3 0.0 1.6 2 0 0 2 2 1 0 AAA domain MMR_HSR1 PF01926.23 KIY61725.1 - 0.17 12.0 0.4 23 5.1 0.1 2.9 3 0 0 3 3 2 0 50S ribosome-binding GTPase tRNA-synt_1b PF00579.25 KIY61726.1 - 2.4e-19 69.8 0.0 3.6e-18 65.9 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) DUF2235 PF09994.9 KIY61727.1 - 1.5e-91 306.8 0.0 1.9e-91 306.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) BAAT_C PF08840.11 KIY61727.1 - 0.066 13.1 0.0 1 9.2 0.0 2.3 1 1 1 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF2235 PF09994.9 KIY61728.1 - 8.8e-47 159.8 0.0 1e-46 159.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) BAAT_C PF08840.11 KIY61728.1 - 0.003 17.5 0.0 1.6 8.6 0.0 2.1 1 1 1 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal SapC PF07277.11 KIY61728.1 - 0.14 11.7 0.0 0.18 11.4 0.0 1.1 1 0 0 1 1 1 0 SapC DDE_1 PF03184.19 KIY61729.1 - 2e-05 24.3 0.0 3.6e-05 23.5 0.0 1.4 1 1 0 1 1 1 1 DDE superfamily endonuclease GPI-anchored PF10342.9 KIY61730.1 - 5.9e-07 30.2 0.1 8.4e-07 29.7 0.1 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family HNH_2 PF13391.6 KIY61731.1 - 1.6e-05 24.9 0.0 3.9e-05 23.7 0.0 1.7 1 1 0 1 1 1 1 HNH endonuclease 2OG-FeII_Oxy_2 PF13532.6 KIY61732.1 - 3.2e-19 69.9 0.3 9.4e-19 68.4 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily OrfB_Zn_ribbon PF07282.11 KIY61732.1 - 5.1 7.1 13.6 2.5 8.1 3.5 2.6 2 0 0 2 2 2 0 Putative transposase DNA-binding domain DUF678 PF05077.12 KIY61732.1 - 5.1 7.3 8.6 6.7 6.9 2.4 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF678) Glyco_hydro_18 PF00704.28 KIY61733.1 - 2.8e-84 283.5 0.1 3.2e-84 283.3 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 zf-C2H2 PF00096.26 KIY61734.1 - 6.2e-07 29.5 20.6 0.11 13.1 0.5 4.8 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_8 PF15909.5 KIY61734.1 - 5.3e-05 23.4 8.6 0.00012 22.3 2.0 2.5 2 0 0 2 2 2 1 C2H2-type zinc ribbon FOXP-CC PF16159.5 KIY61734.1 - 9.3e-05 23.0 5.8 0.076 13.7 0.1 3.3 1 1 2 3 3 3 2 FOXP coiled-coil domain zf-H2C2_2 PF13465.6 KIY61734.1 - 0.027 14.9 0.7 0.027 14.9 0.7 5.6 6 0 0 6 6 6 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 KIY61734.1 - 0.029 15.2 19.9 0.83 10.7 0.4 5.1 5 0 0 5 5 5 0 C2H2-type zinc finger ORC6 PF05460.13 KIY61734.1 - 1.1 8.5 8.5 1.5 8.0 8.5 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) OrsD PF12013.8 KIY61734.1 - 4.8 7.7 11.7 1.9 8.9 4.9 3.4 2 1 1 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_8 PF15909.5 KIY61735.1 - 0.00091 19.5 8.2 0.29 11.5 0.4 3.7 2 1 1 3 3 3 2 C2H2-type zinc ribbon zf-H2C2_2 PF13465.6 KIY61735.1 - 0.0013 19.1 3.8 0.053 14.0 2.2 6.3 7 0 0 7 7 7 3 Zinc-finger double domain zf-C2H2 PF00096.26 KIY61735.1 - 0.0042 17.5 1.1 0.0042 17.5 1.1 5.8 6 0 0 6 6 6 4 Zinc finger, C2H2 type Fn_bind PF02986.14 KIY61735.1 - 0.012 15.3 0.0 0.036 13.8 0.0 1.8 1 0 0 1 1 1 0 Fibronectin binding repeat zf-C2H2_aberr PF17017.5 KIY61735.1 - 0.2 11.8 6.6 3.6 7.7 0.1 3.2 2 1 1 3 3 3 0 Aberrant zinc-finger HNH_2 PF13391.6 KIY61736.1 - 2.4e-05 24.4 0.0 4.8e-05 23.4 0.0 1.5 1 1 0 1 1 1 1 HNH endonuclease CcdA PF07362.12 KIY61736.1 - 0.084 13.3 0.4 0.38 11.2 0.0 2.2 3 0 0 3 3 3 0 Post-segregation antitoxin CcdA Ferric_reduct PF01794.19 KIY61737.1 - 1.3e-19 70.6 14.9 1.3e-19 70.6 14.9 1.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KIY61737.1 - 2.2e-13 50.6 0.0 8.1e-08 32.5 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KIY61737.1 - 1.7e-11 44.2 0.0 3.2e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain SET PF00856.28 KIY61738.1 - 0.00033 21.1 0.0 0.00062 20.2 0.0 1.5 1 0 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.11 KIY61738.1 - 0.01 16.5 0.0 0.02 15.6 0.0 1.4 1 0 0 1 1 1 0 Rubisco LSMT substrate-binding Sec16_C PF12931.7 KIY61739.1 - 1e-95 320.9 0.0 1.3e-95 320.5 0.0 1.1 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 KIY61739.1 - 6.4e-26 91.3 0.0 1.9e-25 89.8 0.0 1.9 2 0 0 2 2 2 1 Vesicle coat trafficking protein Sec16 mid-region 4HBT_3 PF13622.6 KIY61740.1 - 1.1e-53 183.0 0.0 1.3e-53 182.8 0.0 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 KIY61740.1 - 4.2e-21 75.2 0.0 1.8e-17 63.4 0.0 2.9 2 1 1 3 3 3 2 Acyl-CoA thioesterase DUF3147 PF11345.8 KIY61741.1 - 0.93 9.9 13.7 0.18 12.2 3.3 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3147) DUF4646 PF15496.6 KIY61742.1 - 0.00094 19.8 0.3 0.0057 17.3 0.0 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF4646) Erf4 PF10256.9 KIY61742.1 - 0.082 13.0 0.0 0.19 11.8 0.0 1.5 1 1 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family Ost5 PF05251.12 KIY61743.1 - 2.9e-23 81.9 7.7 3.5e-23 81.6 7.7 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit 5 QCR10 PF09796.9 KIY61743.1 - 0.72 10.0 3.6 5.6 7.1 0.1 2.1 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) TB2_DP1_HVA22 PF03134.19 KIY61744.1 - 1.6e-25 88.8 8.5 3.3e-25 87.8 8.5 1.5 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Involucrin_N PF10583.9 KIY61745.1 - 0.081 13.5 2.0 0.15 12.7 2.0 1.4 1 0 0 1 1 1 0 Involucrin of squamous epithelia N-terminus TFIIS_C PF01096.18 KIY61746.1 - 8.6e-13 47.9 3.9 2.9e-11 43.0 0.1 3.0 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 KIY61746.1 - 3.8e-06 26.7 3.0 1.2e-05 25.0 0.3 2.7 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit zf-ribbon_3 PF13248.6 KIY61746.1 - 1.6e-05 24.1 5.3 0.83 9.1 0.0 3.3 3 0 0 3 3 3 3 zinc-ribbon domain DZR PF12773.7 KIY61746.1 - 5.8e-05 23.0 0.7 0.005 16.8 0.2 2.4 2 0 0 2 2 2 1 Double zinc ribbon OrfB_Zn_ribbon PF07282.11 KIY61746.1 - 0.0014 18.5 1.7 0.4 10.6 0.1 2.3 2 0 0 2 2 2 2 Putative transposase DNA-binding domain zf-RING_2 PF13639.6 KIY61746.1 - 0.0096 16.2 1.8 1.2 9.5 0.9 2.4 2 0 0 2 2 2 1 Ring finger domain Rad50_zn_hook PF04423.14 KIY61746.1 - 0.013 15.3 0.8 0.51 10.2 0.1 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif IBR PF01485.21 KIY61746.1 - 0.017 15.3 0.5 0.33 11.2 0.1 2.2 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain zf-FPG_IleRS PF06827.14 KIY61746.1 - 0.02 14.7 3.8 1.2 9.1 0.3 3.3 3 0 0 3 3 3 0 Zinc finger found in FPG and IleRS DNA_ligase_ZBD PF03119.16 KIY61746.1 - 0.023 14.7 3.5 4.2 7.5 1.0 2.6 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain UPF0547 PF10571.9 KIY61746.1 - 0.028 14.5 4.6 7.1 6.8 0.1 3.2 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 TF_Zn_Ribbon PF08271.12 KIY61746.1 - 0.033 13.7 6.2 0.16 11.5 0.7 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding Lar_restr_allev PF14354.6 KIY61746.1 - 0.033 14.5 5.9 3.7 8.0 0.1 2.7 2 1 0 2 2 2 0 Restriction alleviation protein Lar zf-UDP PF14569.6 KIY61746.1 - 0.049 13.7 1.9 0.13 12.4 1.6 1.9 1 1 0 1 1 1 0 Zinc-binding RING-finger Mu-like_Com PF10122.9 KIY61746.1 - 0.065 12.7 5.6 7 6.2 0.3 3.2 2 1 1 3 3 3 0 Mu-like prophage protein Com zf-Sec23_Sec24 PF04810.15 KIY61746.1 - 0.087 12.9 2.1 5.7 7.1 0.0 3.3 2 1 1 3 3 3 0 Sec23/Sec24 zinc finger zinc_ribbon_2 PF13240.6 KIY61746.1 - 0.1 12.4 8.9 11 5.9 3.8 3.2 2 1 0 2 2 2 0 zinc-ribbon domain zf-NADH-PPase PF09297.11 KIY61746.1 - 0.16 11.6 7.6 0.91 9.2 1.6 3.1 2 1 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain PHD PF00628.29 KIY61746.1 - 0.16 11.8 4.3 0.22 11.5 1.1 2.2 2 0 0 2 2 2 0 PHD-finger Zn-ribbon_8 PF09723.10 KIY61746.1 - 0.18 11.9 6.1 15 5.8 0.1 3.2 2 1 1 3 3 3 0 Zinc ribbon domain zf-IS66 PF13005.7 KIY61746.1 - 0.21 12.0 8.0 17 5.9 0.1 3.3 2 1 1 3 3 3 0 zinc-finger binding domain of transposase IS66 CpXC PF14353.6 KIY61746.1 - 0.21 11.6 4.7 6.8 6.8 0.2 2.9 1 1 1 3 3 3 0 CpXC protein zf-RING_7 PF02591.15 KIY61746.1 - 0.26 11.5 6.5 3.3 8.0 0.0 3.0 3 0 0 3 3 3 0 C4-type zinc ribbon domain zf_UBZ PF18439.1 KIY61746.1 - 0.31 10.7 3.5 6.7 6.4 0.1 3.1 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-C2H2_3 PF13878.6 KIY61746.1 - 0.35 10.7 4.9 10 6.1 0.2 3.0 2 1 1 3 3 3 0 zinc-finger of acetyl-transferase ESCO zinc_ribbon_4 PF13717.6 KIY61746.1 - 0.38 10.7 5.9 5.6 7.0 1.3 3.1 2 1 0 2 2 2 0 zinc-ribbon domain RecR PF02132.15 KIY61746.1 - 0.59 9.7 5.9 19 4.9 2.8 2.8 2 1 0 2 2 2 0 RecR protein zf-C3HC4 PF00097.25 KIY61746.1 - 0.6 10.0 5.0 7 6.6 1.9 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Nudix_N_2 PF14803.6 KIY61746.1 - 0.61 10.0 7.4 1.8 8.5 2.1 3.0 2 1 0 2 2 2 0 Nudix N-terminal Prok-RING_1 PF14446.6 KIY61746.1 - 1.1 9.2 6.8 19 5.3 2.9 2.6 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RRN7 PF11781.8 KIY61746.1 - 1.4 8.6 10.1 2.7 7.7 0.5 4.0 4 1 0 4 4 4 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zf-C3HC4_2 PF13923.6 KIY61746.1 - 1.6 8.7 6.8 16 5.4 0.1 2.7 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Zn_Tnp_IS1595 PF12760.7 KIY61746.1 - 1.7 8.7 5.4 9.1 6.3 0.1 3.0 2 1 1 3 3 3 0 Transposase zinc-ribbon domain Zn-C2H2_12 PF18112.1 KIY61746.1 - 2.2 8.8 4.5 22 5.6 0.4 2.4 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain Rubredoxin_2 PF18073.1 KIY61746.1 - 2.2 8.1 7.1 7.5 6.4 0.3 3.1 3 0 0 3 3 3 0 Rubredoxin metal binding domain zf-RING_UBOX PF13445.6 KIY61746.1 - 4.9 7.3 7.5 6.6 6.9 2.7 2.4 2 0 0 2 2 2 0 RING-type zinc-finger A2L_zn_ribbon PF08792.10 KIY61746.1 - 5.6 6.8 6.8 45 3.9 0.1 3.2 3 0 0 3 3 3 0 A2L zinc ribbon domain Kelch_4 PF13418.6 KIY61747.1 - 7.9e-34 115.4 16.9 3.5e-07 30.1 0.2 6.1 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 KIY61747.1 - 5.7e-31 106.2 7.1 2.4e-07 30.9 0.0 6.2 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_1 PF01344.25 KIY61747.1 - 4.1e-30 103.1 11.4 9.1e-06 25.2 0.7 6.2 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 KIY61747.1 - 5e-30 102.8 13.1 2.3e-06 27.7 0.5 6.2 4 2 2 6 6 6 6 Kelch motif Kelch_5 PF13854.6 KIY61747.1 - 1.5e-28 98.3 8.5 7.3e-07 29.0 0.0 6.0 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.15 KIY61747.1 - 1.7e-20 72.1 10.8 4.6e-05 23.2 0.1 6.4 6 0 0 6 6 6 5 Kelch motif PQQ_3 PF13570.6 KIY61747.1 - 0.028 14.9 2.3 19 5.9 0.1 4.9 5 0 0 5 5 5 0 PQQ-like domain F-box-like PF12937.7 KIY61748.1 - 3.6e-10 39.6 2.2 4.3e-10 39.3 0.2 2.3 2 0 0 2 2 2 1 F-box-like Pkinase PF00069.25 KIY61749.1 - 3e-47 161.2 0.0 4.5e-47 160.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY61749.1 - 5e-47 160.4 0.0 7.1e-47 159.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 KIY61749.1 - 1.1e-07 31.6 1.6 2.4e-07 30.5 1.6 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) APH PF01636.23 KIY61749.1 - 0.013 15.5 0.0 0.021 14.8 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 KIY61749.1 - 0.016 14.6 0.0 0.026 13.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family C1_2 PF03107.16 KIY61749.1 - 0.018 15.3 0.6 0.038 14.3 0.6 1.5 1 0 0 1 1 1 0 C1 domain PHD PF00628.29 KIY61749.1 - 0.046 13.6 4.5 0.094 12.6 4.5 1.5 1 0 0 1 1 1 0 PHD-finger Haspin_kinase PF12330.8 KIY61749.1 - 0.049 12.6 0.0 0.1 11.5 0.0 1.4 2 0 0 2 2 2 0 Haspin like kinase domain Kinase-like PF14531.6 KIY61749.1 - 0.16 11.3 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like FBPase PF00316.20 KIY61750.1 - 0.11 12.0 0.1 0.17 11.3 0.1 1.2 1 0 0 1 1 1 0 Fructose-1-6-bisphosphatase, N-terminal domain Med3 PF11593.8 KIY61750.1 - 2.7 7.1 6.2 3.2 6.8 6.2 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal F-box-like PF12937.7 KIY61751.1 - 1.8e-06 27.8 3.2 4.5e-06 26.5 3.2 1.7 1 0 0 1 1 1 1 F-box-like DUF4407 PF14362.6 KIY61755.1 - 3.3 7.0 5.1 23 4.2 2.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Endonuc_Holl PF10107.9 KIY61756.1 - 0.63 9.9 2.3 1.3 8.8 2.3 1.5 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase Zn_clus PF00172.18 KIY61758.1 - 0.47 10.6 11.2 0.068 13.3 4.0 2.3 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF733 PF05306.11 KIY61760.1 - 0.034 14.5 0.1 0.05 13.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF733) Cep57_MT_bd PF06657.13 KIY61760.1 - 0.09 13.2 0.8 0.16 12.4 0.8 1.4 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 DUF2452 PF10504.9 KIY61760.1 - 0.18 11.3 0.3 0.25 10.8 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2452) Zn_clus PF00172.18 KIY61761.1 - 0.01 16.0 10.0 0.055 13.6 1.7 2.4 1 1 1 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF745 PF05335.13 KIY61761.1 - 0.05 13.3 3.3 0.067 12.9 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Snapin_Pallidin PF14712.6 KIY61761.1 - 0.11 13.0 3.9 0.079 13.4 1.8 1.8 2 0 0 2 2 2 0 Snapin/Pallidin Nup54 PF13874.6 KIY61761.1 - 0.17 12.0 8.8 0.24 11.5 8.8 1.1 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 UDPGT PF00201.18 KIY61767.1 - 9e-18 64.3 0.0 1.2e-17 63.9 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 KIY61767.1 - 0.18 11.8 0.0 0.33 10.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Pkinase PF00069.25 KIY61768.1 - 2.8e-18 66.3 0.0 1e-17 64.4 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY61768.1 - 1.3e-12 47.6 0.0 1.9e-11 43.8 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.22 KIY61768.1 - 0.0034 17.0 0.1 0.0058 16.2 0.1 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KIY61768.1 - 0.0097 15.9 0.1 0.029 14.3 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family UBA PF00627.31 KIY61769.1 - 0.12 12.4 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 UBA/TS-N domain Pro-MCH PF05824.12 KIY61769.1 - 0.18 11.7 0.9 3.5 7.6 0.2 2.4 1 1 1 2 2 2 0 Pro-melanin-concentrating hormone (Pro-MCH) Phage_sheath_1N PF17481.2 KIY61769.1 - 0.25 11.9 5.9 0.45 11.0 5.1 1.8 1 1 0 1 1 1 0 Phage tail sheath protein beta-sandwich domain EphA2_TM PF14575.6 KIY61770.1 - 0.033 15.1 0.0 1.1 10.2 0.0 2.6 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain SIT PF15330.6 KIY61770.1 - 0.034 14.6 0.0 1.1 9.7 0.1 2.5 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT WBP-1 PF11669.8 KIY61770.1 - 0.21 12.2 0.5 23 5.7 0.0 3.0 2 0 0 2 2 2 0 WW domain-binding protein 1 PDZ_5 PF17817.1 KIY61771.1 - 0.0013 19.0 0.1 0.03 14.6 0.0 3.2 2 0 0 2 2 2 1 PDZ domain TLP1_add_C PF18313.1 KIY61771.1 - 0.074 13.0 0.2 0.19 11.7 0.2 1.7 1 0 0 1 1 1 0 Thiolase-like protein type 1 additional C-terminal domain Aspzincin_M35 PF14521.6 KIY61772.1 - 6.7e-31 107.8 1.8 6.7e-31 107.8 1.8 2.2 3 0 0 3 3 3 1 Lysine-specific metallo-endopeptidase Peptidase_M35 PF02102.15 KIY61772.1 - 1.6e-08 33.9 22.9 1.2e-07 31.0 22.9 2.0 1 1 0 1 1 1 1 Deuterolysin metalloprotease (M35) family HRXXH PF13933.6 KIY61772.1 - 0.0011 18.6 0.8 0.0011 18.6 0.8 2.2 2 1 1 3 3 3 1 Putative peptidase family ZirS_C PF16583.5 KIY61772.1 - 0.043 13.4 0.4 0.08 12.5 0.4 1.4 1 0 0 1 1 1 0 Zinc-regulated secreted antivirulence protein C-terminal domain Hist_deacetyl PF00850.19 KIY61773.1 - 3.4e-51 174.6 0.7 4.5e-51 174.1 0.7 1.1 1 0 0 1 1 1 1 Histone deacetylase domain MFS_1 PF07690.16 KIY61774.1 - 3.2e-13 49.3 36.5 5.1e-13 48.7 36.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 KIY61774.1 - 6.8e-13 48.6 5.9 6.8e-13 48.6 5.9 2.1 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 HXXEE PF13787.6 KIY61774.1 - 2.6 8.9 6.5 0.84 10.5 1.7 2.6 2 1 0 2 2 2 0 Protein of unknown function with HXXEE motif EFG_IV PF03764.18 KIY61775.1 - 1.3e-35 121.8 0.0 1.7e-34 118.2 0.0 2.4 3 0 0 3 3 3 1 Elongation factor G, domain IV EFG_C PF00679.24 KIY61775.1 - 1.1e-22 79.8 0.0 1.9e-22 79.1 0.0 1.4 1 0 0 1 1 1 1 Elongation factor G C-terminus SNF5 PF04855.12 KIY61776.1 - 1.5e-62 211.5 0.1 3.6e-38 131.7 0.0 2.2 1 1 1 2 2 2 2 SNF5 / SMARCB1 / INI1 S36_mt PF10937.8 KIY61776.1 - 0.26 12.9 0.2 0.26 12.9 0.2 3.6 4 0 0 4 4 4 0 Ribosomal protein S36, mitochondrial Nucleo_P87 PF07267.11 KIY61776.1 - 0.28 10.0 4.0 0.41 9.4 4.0 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 GFO_IDH_MocA PF01408.22 KIY61777.1 - 1e-14 55.4 0.0 1.5e-14 54.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold HLH PF00010.26 KIY61778.1 - 5.2e-07 29.5 0.0 9.6e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Zn_clus PF00172.18 KIY61779.1 - 5.4e-08 32.8 5.1 7.7e-08 32.3 5.1 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Trypan_PARP PF05887.11 KIY61780.1 - 0.53 10.3 14.1 1.3 9.0 14.1 1.6 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) KDZ PF18758.1 KIY61781.1 - 1.9e-19 70.2 0.0 2.1e-19 70.0 0.0 1.0 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KIY61782.1 - 1.3e-23 83.2 0.0 2.2e-23 82.4 0.0 1.4 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases zf-B_box PF00643.24 KIY61782.1 - 0.00081 19.5 1.2 0.00081 19.5 1.2 1.8 2 0 0 2 2 2 1 B-box zinc finger CxC1 PF18802.1 KIY61782.1 - 0.0023 18.1 2.2 0.0033 17.5 0.0 2.3 2 2 0 2 2 2 1 CxC1 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 KIY61782.1 - 0.052 13.4 0.3 0.23 11.3 0.0 2.1 2 0 0 2 2 2 0 CxC3 like cysteine cluster associated with KDZ transposases F-box-like PF12937.7 KIY61783.1 - 4.8e-05 23.2 0.9 0.00015 21.6 0.0 2.4 3 0 0 3 3 3 1 F-box-like Hydrolase_4 PF12146.8 KIY61784.1 - 0.057 12.7 0.0 0.099 11.9 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Laminin_II PF06009.12 KIY61787.1 - 0.00038 20.5 1.4 0.00056 19.9 1.4 1.2 1 0 0 1 1 1 1 Laminin Domain II DHR10 PF18595.1 KIY61787.1 - 0.00041 20.4 7.2 0.00041 20.4 7.2 1.6 1 1 0 1 1 1 1 Designed helical repeat protein 10 domain Tropomyosin PF00261.20 KIY61787.1 - 0.0028 17.1 10.8 0.0044 16.4 10.8 1.4 1 0 0 1 1 1 1 Tropomyosin PRKG1_interact PF15898.5 KIY61787.1 - 0.0092 16.9 2.0 0.0092 16.9 2.0 2.1 2 0 0 2 2 2 1 cGMP-dependent protein kinase interacting domain DASH_Spc34 PF08657.10 KIY61787.1 - 0.014 15.2 4.3 0.022 14.6 3.9 1.4 1 1 0 1 1 1 0 DASH complex subunit Spc34 MukE PF04288.13 KIY61787.1 - 0.046 12.7 6.7 0.067 12.1 6.7 1.2 1 0 0 1 1 1 0 MukE-like family DUF948 PF06103.11 KIY61787.1 - 0.048 13.9 0.8 0.093 13.0 0.4 1.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Spc7 PF08317.11 KIY61787.1 - 0.1 11.4 5.0 0.14 11.0 5.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein CSN5_C PF18323.1 KIY61787.1 - 0.14 13.1 8.9 0.44 11.5 2.9 2.9 1 1 2 3 3 3 0 Cop9 signalosome subunit 5 C-terminal domain DUF848 PF05852.11 KIY61787.1 - 0.14 12.2 5.4 0.24 11.5 4.7 1.7 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Zn_clus PF00172.18 KIY61787.1 - 0.18 11.9 12.2 0.28 11.3 2.9 2.2 1 1 1 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Rhabdo_ncap PF00945.18 KIY61787.1 - 0.26 10.1 2.7 0.36 9.7 2.7 1.2 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein TMPIT PF07851.13 KIY61787.1 - 0.45 9.7 1.4 0.59 9.3 1.4 1.1 1 0 0 1 1 1 0 TMPIT-like protein Jnk-SapK_ap_N PF09744.9 KIY61787.1 - 0.49 10.6 11.1 0.14 12.4 1.8 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 FUSC PF04632.12 KIY61787.1 - 0.5 8.8 2.2 0.55 8.7 2.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family ZapB PF06005.12 KIY61787.1 - 1.1 9.8 7.1 5 7.7 1.8 2.4 2 0 0 2 2 2 0 Cell division protein ZapB Pes-10 PF07149.11 KIY61787.1 - 5.2 6.0 11.2 6.9 5.6 11.2 1.2 1 0 0 1 1 1 0 Pes-10 DUF2457 PF10446.9 KIY61787.1 - 5.9 5.9 19.9 8.2 5.4 19.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DASH_Spc19 PF08287.11 KIY61787.1 - 6.5 6.6 10.4 51 3.7 8.4 2.4 1 1 0 1 1 1 0 Spc19 Plavaka PF18759.1 KIY61789.1 - 4.5e-109 364.6 0.0 6.2e-109 364.2 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase Trypan_PARP PF05887.11 KIY61789.1 - 0.65 10.0 9.3 2.2 8.3 4.8 2.3 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) DUF5067 PF16729.5 KIY61793.1 - 0.08 12.9 0.4 0.13 12.2 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5067) Acyl-CoA_dh_1 PF00441.24 KIY61794.1 - 1e-43 149.1 0.9 1.5e-43 148.6 0.9 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KIY61794.1 - 8.9e-23 80.3 0.0 1.6e-22 79.5 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KIY61794.1 - 3.6e-20 72.6 0.1 5.9e-20 71.9 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KIY61794.1 - 1.6e-16 61.0 0.1 5e-16 59.4 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_ox_N PF14749.6 KIY61794.1 - 0.017 15.6 0.0 0.03 14.9 0.0 1.4 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal WD40 PF00400.32 KIY61795.1 - 2.7e-18 66.0 14.0 0.0011 19.8 0.0 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY61795.1 - 8.3e-07 29.2 0.1 0.1 12.9 0.0 3.8 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain ThiF PF00899.21 KIY61796.1 - 3.6e-68 229.5 0.0 5.2e-68 229.0 0.0 1.1 1 0 0 1 1 1 1 ThiF family UBA_e1_thiolCys PF10585.9 KIY61796.1 - 0.00011 22.2 0.0 0.011 15.7 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.6 KIY61796.1 - 0.0058 17.1 0.0 0.028 14.9 0.0 2.1 1 1 0 1 1 1 1 Putative NAD(P)-binding WD40 PF00400.32 KIY61797.1 - 4.8e-50 166.5 12.7 8e-09 36.0 0.4 7.8 7 2 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY61797.1 - 1.9e-13 50.5 2.7 0.0001 22.5 0.1 4.8 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIY61797.1 - 1.5e-09 37.1 5.6 0.0062 15.2 0.0 4.8 3 2 1 5 5 5 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 KIY61797.1 - 8.9e-06 24.5 1.2 0.032 12.8 0.0 2.5 3 0 0 3 3 3 2 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 KIY61797.1 - 0.00088 18.3 1.4 0.6 9.0 0.0 3.6 1 1 3 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KIY61797.1 - 0.0058 16.5 0.7 4.6 7.1 0.0 3.1 2 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A DUF1513 PF07433.11 KIY61797.1 - 0.0076 15.4 1.2 0.27 10.3 0.1 3.3 2 2 1 3 3 3 1 Protein of unknown function (DUF1513) Retrotrans_gag PF03732.17 KIY61798.1 - 0.00013 22.1 0.3 0.00018 21.7 0.3 1.2 1 0 0 1 1 1 1 Retrotransposon gag protein Cupin_8 PF13621.6 KIY61798.1 - 0.06 13.1 0.0 0.072 12.8 0.0 1.1 1 0 0 1 1 1 0 Cupin-like domain SeqA_N PF17206.3 KIY61799.1 - 0.71 9.2 2.2 13 5.2 0.0 2.8 3 0 0 3 3 3 0 SeqA protein N-terminal domain AT_hook PF02178.19 KIY61802.1 - 0.011 15.5 0.3 0.025 14.4 0.3 1.7 1 0 0 1 1 1 0 AT hook motif PHINT_rpt PF14882.6 KIY61802.1 - 0.11 12.8 0.1 0.3 11.4 0.0 1.7 2 0 0 2 2 2 0 Phage-integrase repeat unit KDZ PF18758.1 KIY61804.1 - 5.5e-53 179.9 2.0 1.1e-52 178.8 2.0 1.5 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KIY61804.1 - 3.8e-29 101.0 0.0 2e-28 98.7 0.0 2.1 2 0 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KIY61804.1 - 3.6e-05 23.9 0.0 0.00011 22.3 0.0 1.8 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases zf-UBR PF02207.20 KIY61804.1 - 2.5 8.4 8.9 0.86 9.8 5.0 2.3 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) Polysacc_deac_1 PF01522.21 KIY61805.1 - 5.4e-27 94.2 0.0 8.1e-27 93.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 KIY61805.1 - 0.02 14.1 0.0 0.026 13.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 Metallophos PF00149.28 KIY61806.1 - 2.1e-35 123.1 0.1 3.8e-35 122.2 0.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase zf-MYND PF01753.18 KIY61807.1 - 1e-07 31.9 15.0 2.6e-07 30.6 15.0 1.7 1 0 0 1 1 1 1 MYND finger Methyltransf_11 PF08241.12 KIY61808.1 - 1.9e-18 66.9 0.0 5.3e-18 65.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIY61808.1 - 2.7e-18 66.4 0.0 7e-18 65.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIY61808.1 - 4.2e-11 42.9 0.0 6.4e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIY61808.1 - 1.6e-09 38.4 0.0 2.9e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIY61808.1 - 5.8e-09 35.6 0.0 8.3e-09 35.1 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KIY61808.1 - 6e-07 29.5 0.0 8.4e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 KIY61808.1 - 0.021 14.4 0.0 0.037 13.6 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW PCMT PF01135.19 KIY61808.1 - 0.091 12.5 0.0 0.24 11.1 0.0 1.7 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) F-box PF00646.33 KIY61809.1 - 1.7e-06 27.7 1.7 3.2e-06 26.9 1.7 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KIY61809.1 - 6.9e-05 22.7 0.5 0.00013 21.7 0.5 1.5 1 0 0 1 1 1 1 F-box-like SatRNA_48 PF17485.2 KIY61810.1 - 0.11 11.6 0.9 0.13 11.4 0.1 1.4 2 0 0 2 2 2 0 Satellite RNA 48 kDa protein OrsD PF12013.8 KIY61810.1 - 0.53 10.8 4.7 0.23 11.9 0.7 2.3 2 0 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf_UBZ PF18439.1 KIY61810.1 - 1.6 8.4 7.9 3.3 7.4 2.2 2.6 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger BTB PF00651.31 KIY61812.1 - 2.2e-06 27.9 0.0 2.8e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 BTB/POZ domain KDZ PF18758.1 KIY61813.1 - 6.1e-50 169.9 0.0 1.1e-49 169.1 0.0 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KIY61813.1 - 1e-28 99.6 0.0 2.4e-28 98.4 0.0 1.6 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KIY61813.1 - 1.6e-06 28.2 0.0 4.1e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases MukB PF04310.12 KIY61813.1 - 0.35 10.6 1.0 0.68 9.7 0.3 1.8 2 0 0 2 2 2 0 MukB N-terminal PSI_integrin PF17205.3 KIY61813.1 - 5.5 6.8 7.5 1.8 8.3 2.0 2.5 2 0 0 2 2 2 0 Integrin plexin domain zf-RING_UBOX PF13445.6 KIY61814.1 - 0.043 13.8 0.3 0.08 13.0 0.3 1.4 1 0 0 1 1 1 0 RING-type zinc-finger DUF3402 PF11882.8 KIY61815.1 - 5.8 5.9 5.9 10 5.1 5.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3402) AIM3 PF17096.5 KIY61816.1 - 0.043 14.7 0.5 0.06 14.3 0.5 1.2 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 Spc7_N PF15402.6 KIY61816.1 - 1.2 7.2 5.1 1.5 7.0 5.1 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 IGR PF09597.10 KIY61821.1 - 0.052 13.7 0.1 0.14 12.3 0.1 1.6 1 0 0 1 1 1 0 IGR protein motif SLY PF12485.8 KIY61823.1 - 0.054 14.2 0.3 0.054 14.2 0.3 2.7 3 1 1 4 4 4 0 Lymphocyte signaling adaptor protein PITH PF06201.13 KIY61825.1 - 5.9e-36 124.0 0.0 7.5e-36 123.6 0.0 1.1 1 0 0 1 1 1 1 PITH domain Abhydrolase_1 PF00561.20 KIY61826.1 - 6.9e-26 91.4 0.1 1.3e-25 90.5 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 KIY61826.1 - 3.4e-23 81.0 0.3 1.1e-22 79.4 0.0 2.0 2 0 0 2 2 2 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 KIY61826.1 - 9.6e-05 21.8 0.0 0.0028 17.0 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 FSH1 PF03959.13 KIY61826.1 - 0.0015 18.2 0.0 0.069 12.8 0.0 2.2 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Pkinase PF00069.25 KIY61827.1 - 2.7e-59 200.7 0.0 5.7e-59 199.6 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY61827.1 - 7.1e-25 87.8 0.0 6.9e-15 55.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.24 KIY61827.1 - 4.1e-05 24.2 2.0 0.00028 21.5 2.0 2.6 1 1 0 1 1 1 1 Protein kinase C terminal domain APH PF01636.23 KIY61827.1 - 0.0049 16.8 0.4 3.1 7.7 0.1 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family FTA2 PF13095.6 KIY61827.1 - 0.0083 15.8 0.0 2.4 7.8 0.0 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KIY61827.1 - 0.027 13.8 0.0 0.058 12.7 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KIY61827.1 - 0.15 11.3 0.0 2.7 7.2 0.0 2.3 2 0 0 2 2 2 0 Kinase-like zf-C2H2 PF00096.26 KIY61828.1 - 5e-26 89.7 67.4 0.0032 17.8 5.7 10.4 10 0 0 10 10 10 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIY61828.1 - 2e-18 65.5 63.4 0.065 14.1 0.1 10.7 10 0 0 10 10 10 10 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KIY61828.1 - 5.8e-07 29.7 20.0 0.019 15.3 0.2 4.8 2 1 3 5 5 5 4 C2H2-type zinc ribbon zf-H2C2_2 PF13465.6 KIY61828.1 - 4e-05 23.8 0.9 4e-05 23.8 0.9 11.8 13 0 0 13 13 13 4 Zinc-finger double domain zf-C2H2_6 PF13912.6 KIY61828.1 - 0.021 14.8 30.6 0.64 10.1 2.1 6.7 7 0 0 7 7 7 0 C2H2-type zinc finger DUF5040 PF16443.5 KIY61828.1 - 0.09 12.2 0.3 2.8 7.3 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5040) zf-C2H2_jaz PF12171.8 KIY61828.1 - 0.18 12.1 25.7 15 6.0 0.3 8.0 8 0 0 8 8 8 0 Zinc-finger double-stranded RNA-binding zf-C2H2_aberr PF17017.5 KIY61828.1 - 6.3 6.9 29.4 4.9 7.3 3.1 6.2 2 1 3 6 6 6 0 Aberrant zinc-finger Cir_N PF10197.9 KIY61830.1 - 1.3e-06 28.4 0.3 1.3e-06 28.4 0.3 2.9 3 0 0 3 3 3 1 N-terminal domain of CBF1 interacting co-repressor CIR DUF5112 PF17139.4 KIY61830.1 - 0.14 11.6 0.9 0.21 11.0 0.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5112) HMG_box PF00505.19 KIY61831.1 - 2.9e-15 56.4 0.2 3.4e-15 56.2 0.2 1.0 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KIY61831.1 - 0.0022 18.5 0.1 0.0026 18.3 0.1 1.1 1 0 0 1 1 1 1 HMG-box domain NMT1_3 PF16868.5 KIY61832.1 - 0.098 12.1 0.1 0.12 11.8 0.1 1.1 1 0 0 1 1 1 0 NMT1-like family WD40 PF00400.32 KIY61833.1 - 2.9e-26 91.2 12.7 2.5e-09 37.6 0.0 5.8 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY61833.1 - 3e-07 30.7 0.0 0.0032 17.7 0.0 3.9 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIY61833.1 - 0.0043 16.0 0.0 0.085 11.8 0.0 2.8 2 2 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF2358 PF10184.9 KIY61834.1 - 0.0019 18.5 0.0 0.003 17.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) Replicase PF03090.17 KIY61834.1 - 0.091 12.6 0.1 0.16 11.8 0.1 1.4 1 0 0 1 1 1 0 Replicase family APG12 PF04110.13 KIY61835.1 - 0.17 12.3 0.0 0.33 11.4 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-like autophagy protein Apg12 EST1_DNA_bind PF10373.9 KIY61836.1 - 0.00029 20.4 0.0 0.5 9.8 0.0 2.3 2 0 0 2 2 2 2 Est1 DNA/RNA binding domain PUF PF00806.19 KIY61837.1 - 6.2e-13 47.7 0.0 0.0086 15.7 0.0 5.8 5 0 0 5 5 5 5 Pumilio-family RNA binding repeat Acyl-CoA_dh_1 PF00441.24 KIY61838.1 - 3.1e-28 98.9 1.3 4.4e-28 98.4 1.3 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KIY61838.1 - 3.7e-16 59.1 1.0 9.5e-16 57.8 1.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.28 KIY61838.1 - 1.9e-15 56.8 0.0 4.2e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.16 KIY61838.1 - 7.9e-14 52.3 0.0 1.8e-13 51.2 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KIY61838.1 - 9.8e-05 22.6 0.1 0.00019 21.7 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain RPAP1_C PF08620.10 KIY61839.1 - 2.3e-17 62.8 0.1 6.2e-17 61.5 0.1 1.7 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 KIY61839.1 - 5.3e-07 29.3 1.5 1.1e-06 28.3 1.5 1.6 1 0 0 1 1 1 1 RPAP1-like, N-terminal MFS_1 PF07690.16 KIY61840.1 - 2.7e-27 95.7 44.6 1.3e-20 73.7 14.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily F-box-like PF12937.7 KIY61841.1 - 2.3e-09 37.0 0.2 2.3e-09 37.0 0.2 2.6 2 1 0 2 2 2 1 F-box-like ddrB-ParB PF18763.1 KIY61842.1 - 0.022 14.8 0.0 0.038 14.1 0.0 1.3 1 0 0 1 1 1 0 ddrB-like ParB superfamily domain Oxidored_FMN PF00724.20 KIY61846.1 - 1.2e-95 320.7 0.0 1.3e-95 320.5 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family TPR_9 PF13371.6 KIY61848.1 - 0.00011 22.2 0.4 0.0078 16.3 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 KIY61848.1 - 0.16 12.4 0.0 13 6.5 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat AP3D1 PF06375.11 KIY61848.1 - 4.4 7.5 11.2 0.89 9.8 5.0 2.3 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 Pkinase PF00069.25 KIY61849.1 - 4.8e-08 32.7 0.0 2e-07 30.6 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Alanine_zipper PF11839.8 KIY61850.1 - 0.029 14.7 2.4 0.029 14.7 2.4 2.8 3 0 0 3 3 3 0 Alanine-zipper, major outer membrane lipoprotein Laminin_I PF06008.14 KIY61850.1 - 0.042 13.6 5.7 0.3 10.8 0.2 2.2 2 0 0 2 2 2 0 Laminin Domain I DUF948 PF06103.11 KIY61850.1 - 0.062 13.6 2.5 6.5 7.1 0.8 3.3 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) F-box-like PF12937.7 KIY61851.1 - 0.0069 16.3 0.5 0.0069 16.3 0.5 2.3 3 0 0 3 3 3 1 F-box-like Phage_integrase PF00589.22 KIY61852.1 - 3.6e-06 26.9 0.0 7.3e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Phage integrase family tRNA_synt_1c_R2 PF04557.15 KIY61852.1 - 0.024 15.6 0.6 0.048 14.6 0.6 1.5 1 0 0 1 1 1 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 F-box-like PF12937.7 KIY61854.1 - 0.0093 15.8 0.1 0.027 14.4 0.1 1.8 1 0 0 1 1 1 1 F-box-like Acetyltransf_3 PF13302.7 KIY61855.1 - 8.8e-19 68.6 0.0 1.4e-18 67.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIY61855.1 - 4.9e-07 30.0 0.0 9.5e-07 29.1 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 KIY61855.1 - 0.0024 17.6 0.0 0.0037 17.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF2824 PF11039.8 KIY61855.1 - 0.015 15.3 0.0 0.019 14.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2824) FR47 PF08445.10 KIY61855.1 - 0.057 13.4 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_3 PF13302.7 KIY61856.1 - 7.2e-19 68.8 0.0 1e-18 68.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIY61856.1 - 2.5e-07 30.9 0.0 5.1e-07 29.9 0.0 1.5 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 KIY61856.1 - 0.00068 19.3 0.0 0.0015 18.3 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIY61856.1 - 0.015 15.3 0.0 0.034 14.1 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein DUF2824 PF11039.8 KIY61856.1 - 0.079 12.9 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2824) HIT PF01230.23 KIY61857.1 - 3.2e-16 59.9 0.0 6.3e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KIY61857.1 - 5.5e-11 43.0 0.0 8.1e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 KIY61857.1 - 0.0051 16.7 0.0 0.0073 16.2 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 EBV-NA1 PF02905.14 KIY61857.1 - 0.11 12.3 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Epstein Barr virus nuclear antigen-1, DNA-binding domain TRAPPC10 PF12584.8 KIY61857.1 - 0.16 11.7 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Trafficking protein particle complex subunit 10, TRAPPC10 She9_MDM33 PF05546.11 KIY61858.1 - 5e-70 235.4 8.5 6.9e-70 234.9 8.5 1.1 1 0 0 1 1 1 1 She9 / Mdm33 family F-box-like PF12937.7 KIY61862.1 - 3.7e-07 29.9 0.1 7.7e-06 25.7 0.0 2.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIY61862.1 - 0.0013 18.5 0.3 0.093 12.6 0.1 2.9 2 0 0 2 2 2 1 F-box domain APG6_N PF17675.1 KIY61863.1 - 9.4e-05 22.9 16.9 9.4e-05 22.9 16.9 4.1 2 1 1 3 3 3 1 Apg6 coiled-coil region Spc7 PF08317.11 KIY61863.1 - 0.002 17.0 12.4 0.002 17.0 12.4 3.7 2 1 2 4 4 4 1 Spc7 kinetochore protein XhlA PF10779.9 KIY61863.1 - 0.034 14.4 16.8 2.1 8.6 0.6 4.9 4 0 0 4 4 4 0 Haemolysin XhlA Ribosomal_S30 PF04758.14 KIY61863.1 - 0.07 13.3 1.9 0.93 9.7 0.4 2.6 2 0 0 2 2 2 0 Ribosomal protein S30 XRN_M PF17846.1 KIY61863.1 - 1.5 7.7 0.0 1.5 7.7 0.0 3.7 2 1 2 4 4 4 0 Xrn1 helical domain FAM221 PF14753.6 KIY61865.1 - 0.27 10.8 0.3 0.51 9.9 0.3 1.4 1 0 0 1 1 1 0 Protein FAM221A/B RRM_1 PF00076.22 KIY61867.1 - 2.9e-08 33.4 0.0 5.2e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KIY61867.1 - 2.9e-05 23.9 0.0 0.0001 22.1 0.0 1.8 2 0 0 2 2 2 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 KIY61867.1 - 0.00083 19.3 0.0 0.0017 18.3 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KIY61867.1 - 0.00092 19.2 0.2 0.0029 17.6 0.0 1.9 2 0 0 2 2 2 1 RNA binding motif PriX PF18689.1 KIY61867.1 - 0.14 12.6 0.0 0.31 11.4 0.0 1.6 1 0 0 1 1 1 0 Primase X Methyltransf_11 PF08241.12 KIY61868.1 - 4.3e-17 62.6 0.0 8.9e-17 61.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIY61868.1 - 3.6e-16 59.3 0.0 5.7e-16 58.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIY61868.1 - 7.8e-15 55.1 0.0 1.2e-14 54.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIY61868.1 - 2.4e-14 53.9 0.0 4.4e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIY61868.1 - 2.5e-13 50.6 0.1 7.2e-13 49.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.11 KIY61868.1 - 1.7e-07 30.4 0.0 2.3e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Ubie_methyltran PF01209.18 KIY61868.1 - 2.6e-07 30.2 0.0 6.5e-07 28.9 0.0 1.6 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KIY61868.1 - 1.1e-06 28.4 0.0 1.5e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain DREV PF05219.12 KIY61868.1 - 6.6e-05 22.1 0.0 8.7e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase MetW PF07021.12 KIY61868.1 - 0.0003 20.4 0.0 0.00046 19.8 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PCMT PF01135.19 KIY61868.1 - 0.0019 18.0 0.0 0.0037 17.1 0.0 1.6 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 KIY61868.1 - 0.0023 17.9 0.0 0.0046 17.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KIY61868.1 - 0.014 14.7 0.0 0.018 14.3 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase PrmA PF06325.13 KIY61868.1 - 0.046 13.1 0.0 0.067 12.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltr_RsmB-F PF01189.17 KIY61868.1 - 0.058 13.0 0.0 0.22 11.2 0.0 1.8 1 1 1 2 2 2 0 16S rRNA methyltransferase RsmB/F TAP42 PF04177.12 KIY61869.1 - 8.1e-80 268.3 0.7 9.2e-80 268.1 0.7 1.0 1 0 0 1 1 1 1 TAP42-like family DUF4455 PF14643.6 KIY61869.1 - 0.048 12.3 5.4 1.9 7.0 2.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4455) Mt_ATP-synt_D PF05873.12 KIY61869.1 - 0.079 12.8 0.7 0.2 11.5 0.7 1.6 1 0 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) Nop25 PF09805.9 KIY61869.1 - 2.6 8.5 12.0 0.28 11.7 3.1 2.2 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) Myb_DNA-bind_7 PF15963.5 KIY61869.1 - 4 7.4 7.0 1.9 8.4 0.8 2.5 2 1 1 3 3 3 0 Myb DNA-binding like Complex1_LYR PF05347.15 KIY61870.1 - 1.4e-10 41.1 0.0 1.7e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) HIG_1_N PF04588.13 KIY61871.1 - 1.5e-17 63.6 1.7 2.4e-17 62.9 1.7 1.3 1 0 0 1 1 1 1 Hypoxia induced protein conserved region 6PF2K PF01591.18 KIY61871.1 - 0.00097 18.5 0.1 0.0013 18.0 0.1 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase MAP17 PF15807.5 KIY61871.1 - 0.17 12.1 2.8 0.49 10.6 2.8 1.7 1 1 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Otopetrin PF03189.13 KIY61871.1 - 0.22 10.3 0.0 0.25 10.1 0.0 1.1 1 0 0 1 1 1 0 Otopetrin UAA PF08449.11 KIY61872.1 - 1.6e-74 250.9 16.6 2e-74 250.5 16.6 1.0 1 0 0 1 1 1 1 UAA transporter family PUNUT PF16913.5 KIY61872.1 - 5e-07 29.2 16.8 1.5e-05 24.4 16.8 2.1 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport EamA PF00892.20 KIY61872.1 - 7.2e-06 26.2 27.5 0.0032 17.7 5.3 2.9 2 1 0 3 3 3 2 EamA-like transporter family CRT-like PF08627.10 KIY61872.1 - 0.00013 21.1 4.1 0.00019 20.5 4.0 1.5 1 1 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like TPT PF03151.16 KIY61872.1 - 0.00045 19.7 11.8 0.00063 19.2 11.8 1.3 1 0 0 1 1 1 1 Triose-phosphate Transporter family SLC35F PF06027.12 KIY61872.1 - 0.0023 17.5 9.4 0.022 14.3 9.4 2.1 1 1 0 1 1 1 1 Solute carrier family 35 DUF4293 PF14126.6 KIY61872.1 - 0.018 15.3 6.8 0.024 14.9 3.6 2.4 2 2 0 2 2 2 0 Domain of unknown function (DUF4293) ASCH PF04266.14 KIY61876.1 - 0.18 12.4 0.0 0.35 11.5 0.0 1.4 1 0 0 1 1 1 0 ASCH domain CxC2 PF18803.1 KIY61877.1 - 2.5e-23 82.3 0.3 7e-23 80.8 0.0 1.9 3 0 0 3 3 3 1 CxC2 like cysteine cluster associated with KDZ transposases KDZ PF18758.1 KIY61877.1 - 2.2e-11 43.8 0.0 3.8e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 KIY61877.1 - 0.012 15.7 0.0 0.039 14.1 0.0 1.9 1 0 0 1 1 1 0 CxC1 like cysteine cluster associated with KDZ transposases KDZ PF18758.1 KIY61878.1 - 5.6e-20 71.9 0.3 6.2e-20 71.8 0.3 1.0 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase WAPL PF07814.13 KIY61879.1 - 3.5e-10 39.2 0.5 9.4e-08 31.2 0.2 2.2 1 1 0 2 2 2 2 Wings apart-like protein regulation of heterochromatin Spem1 PF15670.5 KIY61880.1 - 0.11 12.0 2.2 0.14 11.7 2.2 1.1 1 0 0 1 1 1 0 Spermatid maturation protein 1 CBM_20 PF00686.19 KIY61881.1 - 3.9e-31 106.8 1.0 1e-30 105.5 1.0 1.7 1 0 0 1 1 1 1 Starch binding domain Alpha-amylase PF00128.24 KIY61881.1 - 8.4e-16 58.4 0.0 5e-14 52.6 0.0 2.1 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.18 KIY61881.1 - 2.4e-13 50.4 0.1 1e-12 48.4 0.0 2.1 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain OprD PF03573.13 KIY61882.1 - 0.032 13.3 0.2 0.039 13.0 0.2 1.0 1 0 0 1 1 1 0 outer membrane porin, OprD family Metallophos PF00149.28 KIY61884.1 - 1.3e-35 123.8 0.0 1.9e-35 123.2 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KIY61884.1 - 0.0021 18.5 0.0 0.004 17.6 0.0 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 KIY61884.1 - 0.021 15.0 0.0 0.031 14.5 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain KDZ PF18758.1 KIY61885.1 - 1.2e-45 155.9 0.2 1.8e-45 155.3 0.2 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase YnfE PF17452.2 KIY61885.1 - 0.11 12.8 2.0 10 6.5 0.2 2.9 3 0 0 3 3 3 0 Uncharacterized YnfE-like HetR_C PF18460.1 KIY61885.1 - 0.3 11.0 3.3 0.43 10.5 1.2 2.3 2 0 0 2 2 2 0 Heterocyst differentiation regulator C-terminal Hood domain Cauli_VI PF01693.16 KIY61888.1 - 1.9e-05 24.9 0.2 0.08 13.3 0.0 3.5 3 0 0 3 3 3 2 Caulimovirus viroplasmin Raftlin PF15250.6 KIY61890.1 - 3.9 6.1 6.1 7.7 5.1 6.1 1.4 1 0 0 1 1 1 0 Raftlin Cauli_VI PF01693.16 KIY61891.1 - 0.0027 18.0 3.9 0.039 14.3 0.6 2.9 3 0 0 3 3 3 1 Caulimovirus viroplasmin UPF0240 PF06784.11 KIY61891.1 - 0.14 12.2 0.1 0.21 11.6 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0240) DUF4692 PF15763.5 KIY61891.1 - 0.32 11.5 3.0 0.52 10.8 3.0 1.5 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) KDZ PF18758.1 KIY61896.1 - 5.9e-49 166.7 0.0 8.8e-49 166.1 0.0 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KIY61896.1 - 2.1e-25 88.9 1.1 6.3e-25 87.4 1.1 1.9 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases DUF4556 PF15094.6 KIY61896.1 - 0.12 11.6 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4556) Sec23_trunk PF04811.15 KIY61897.1 - 4e-14 52.8 0.0 1.4e-08 34.7 0.0 2.1 1 1 1 2 2 2 2 Sec23/Sec24 trunk domain zf-Sec23_Sec24 PF04810.15 KIY61897.1 - 1.2e-06 28.4 0.7 3.1e-06 27.1 0.0 1.9 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger F-box-like PF12937.7 KIY61898.1 - 0.011 15.6 0.3 0.03 14.2 0.3 1.8 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 KIY61898.1 - 0.56 10.1 3.3 24 5.0 0.2 2.9 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.7 KIY61899.1 - 0.0083 16.0 0.4 0.0083 16.0 0.4 2.5 3 0 0 3 3 3 1 F-box-like Fungal_trans PF04082.18 KIY61900.1 - 1.6e-08 34.0 1.8 0.0006 18.9 0.3 2.5 2 1 1 3 3 3 2 Fungal specific transcription factor domain NAD_binding_10 PF13460.6 KIY61902.1 - 3.7e-05 23.7 0.0 0.00032 20.7 0.0 2.1 1 1 0 1 1 1 1 NAD(P)H-binding adh_short_C2 PF13561.6 KIY61902.1 - 0.004 16.7 0.0 0.006 16.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase F-box-like PF12937.7 KIY61904.1 - 0.00012 21.9 2.2 0.00037 20.3 2.2 1.9 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KIY61904.1 - 8.5 6.4 7.3 4.2 7.3 0.9 3.2 4 0 0 4 4 4 0 F-box domain CobD_Cbib PF03186.13 KIY61908.1 - 0.037 13.3 0.0 0.066 12.4 0.0 1.4 1 0 0 1 1 1 0 CobD/Cbib protein OrsD PF12013.8 KIY61909.1 - 2e-06 28.2 0.0 4.2e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Orsellinic acid/F9775 biosynthesis cluster protein D zf-H2C2_5 PF13909.6 KIY61909.1 - 9.5e-05 22.1 0.1 0.00028 20.6 0.1 1.8 1 0 0 1 1 1 1 C2H2-type zinc-finger domain CHB_HEX PF03173.13 KIY61909.1 - 0.0086 15.8 0.0 3.6 7.2 0.0 2.5 2 0 0 2 2 2 2 Putative carbohydrate binding domain p450 PF00067.22 KIY61912.1 - 5.9e-68 229.7 0.0 7.5e-68 229.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PWI PF01480.17 KIY61914.1 - 2.5e-26 91.8 0.0 3.8e-26 91.2 0.0 1.2 1 0 0 1 1 1 1 PWI domain F-box-like PF12937.7 KIY61916.1 - 4.1e-06 26.6 3.2 5.7e-06 26.1 1.1 2.4 2 1 0 2 2 2 1 F-box-like LRR_4 PF12799.7 KIY61916.1 - 0.0012 19.2 3.1 0.28 11.7 0.1 3.9 4 0 0 4 4 4 1 Leucine Rich repeats (2 copies) F-box-like_2 PF13013.6 KIY61916.1 - 0.0055 16.7 0.2 0.022 14.7 0.2 2.1 1 0 0 1 1 1 1 F-box-like domain F-box PF00646.33 KIY61916.1 - 0.067 13.1 1.4 9.1 6.3 0.2 3.4 2 0 0 2 2 2 0 F-box domain TFIIF_alpha PF05793.12 KIY61917.1 - 7.8 5.0 7.9 5.4 5.5 6.4 1.4 1 1 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) APC_r PF05923.12 KIY61918.1 - 0.03 14.1 0.2 0.061 13.1 0.2 1.6 1 0 0 1 1 1 0 APC repeat Dynamin_N PF00350.23 KIY61919.1 - 1.6e-26 93.3 0.0 3.2e-26 92.4 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KIY61919.1 - 4.7e-16 58.8 0.1 1.3e-07 31.1 0.0 2.3 2 0 0 2 2 2 2 Dynamin central region GED PF02212.18 KIY61919.1 - 2.3e-07 30.9 0.1 7e-07 29.3 0.1 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KIY61919.1 - 0.00034 20.7 1.1 0.007 16.4 1.1 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.6 KIY61919.1 - 0.019 15.2 1.1 0.047 13.9 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KIY61919.1 - 0.066 13.6 0.0 0.24 11.8 0.0 2.0 1 1 0 1 1 1 0 AAA ATPase domain zf-C2H2_3rep PF18868.1 KIY61919.1 - 0.17 12.5 0.0 0.46 11.2 0.0 1.7 1 0 0 1 1 1 0 Zinc finger C2H2-type, 3 repeats AAA_29 PF13555.6 KIY61919.1 - 0.19 11.5 0.0 0.43 10.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain p450 PF00067.22 KIY61920.1 - 8.2e-56 189.7 0.0 2.7e-47 161.6 0.0 2.7 3 0 0 3 3 3 2 Cytochrome P450 CNF1 PF05785.12 KIY61920.1 - 0.078 12.2 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Rho-activating domain of cytotoxic necrotizing factor IATP PF04568.12 KIY61921.1 - 0.0018 18.7 1.2 0.0022 18.4 1.2 1.2 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP Cellulase PF00150.18 KIY61922.1 - 1.1e-08 34.8 0.0 2.3e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) BTB PF00651.31 KIY61923.1 - 6.8e-05 23.1 0.1 0.0002 21.5 0.1 1.7 1 1 0 1 1 1 1 BTB/POZ domain COesterase PF00135.28 KIY61923.1 - 0.18 10.6 0.0 0.22 10.3 0.0 1.1 1 0 0 1 1 1 0 Carboxylesterase family zf-C2H2_aberr PF17017.5 KIY61929.1 - 0.00047 20.4 2.0 0.61 10.2 0.3 2.2 2 0 0 2 2 2 2 Aberrant zinc-finger zf-C2H2 PF00096.26 KIY61929.1 - 0.0008 19.7 7.6 0.025 15.0 1.3 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIY61929.1 - 0.014 16.2 5.2 1.1 10.3 0.7 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger Tub_N PF16322.5 KIY61933.1 - 9.1 6.6 12.2 0.17 12.3 1.2 2.7 3 0 0 3 3 3 0 Tubby N-terminal F-box-like PF12937.7 KIY61934.1 - 8.7e-06 25.5 3.0 2.2e-05 24.2 3.0 1.8 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KIY61934.1 - 0.00014 22.2 0.1 0.55 10.7 0.1 4.0 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) MARVEL PF01284.23 KIY61935.1 - 0.0026 17.8 7.7 0.0043 17.1 7.5 1.5 1 1 0 1 1 1 1 Membrane-associating domain Bac_export_2 PF01312.19 KIY61935.1 - 0.77 8.9 2.7 0.37 9.9 0.2 1.6 2 0 0 2 2 2 0 FlhB HrpN YscU SpaS Family Vps53_N PF04100.12 KIY61936.1 - 1.1e-87 294.5 5.1 2.1e-87 293.6 5.1 1.4 1 0 0 1 1 1 1 Vps53-like, N-terminal VPS53_C PF16854.5 KIY61936.1 - 2.8e-06 27.4 1.9 0.00019 21.3 0.0 3.3 2 1 1 3 3 3 1 Vacuolar protein sorting-associated protein 53 C-terminus Vps54_N PF10475.9 KIY61936.1 - 0.0013 18.1 7.4 0.0038 16.6 7.4 1.7 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex GAS PF13851.6 KIY61936.1 - 0.11 11.9 11.2 0.22 10.8 11.2 1.5 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Med28 PF11594.8 KIY61936.1 - 0.12 12.4 6.0 0.18 11.9 3.9 2.3 2 0 0 2 2 2 0 Mediator complex subunit 28 DUF1415 PF07209.12 KIY61936.1 - 0.36 10.6 1.9 7.6 6.2 0.4 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF1415) Sec5 PF15469.6 KIY61936.1 - 0.37 10.6 5.7 1.3 8.8 5.7 1.9 1 0 0 1 1 1 0 Exocyst complex component Sec5 DUF4795 PF16043.5 KIY61936.1 - 0.45 10.1 8.0 1.3 8.5 8.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) Vps51 PF08700.11 KIY61936.1 - 0.61 10.2 6.3 4.7 7.3 2.2 3.8 1 1 2 3 3 3 0 Vps51/Vps67 NBD94 PF16830.5 KIY61936.1 - 1 9.8 5.1 3.7 8.0 5.1 2.0 1 0 0 1 1 1 0 Nucleotide-Binding Domain 94 of RH Fib_alpha PF08702.10 KIY61936.1 - 1.1 9.5 15.0 0.37 11.0 10.9 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 KIY61936.1 - 1.6 8.8 15.5 2.1 8.4 6.1 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) RecG_N PF17190.4 KIY61936.1 - 2.7 8.8 6.9 1.5 9.6 1.5 3.0 2 1 1 3 3 3 0 RecG N-terminal helical domain T3SS_needle_E PF08988.10 KIY61936.1 - 3 8.0 6.3 2.8 8.1 0.4 3.1 2 0 0 2 2 2 0 Type III secretion system, cytoplasmic E component of needle FapA PF03961.13 KIY61936.1 - 3.3 6.2 6.3 5.8 5.4 6.3 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A RRP36 PF06102.12 KIY61936.1 - 3.4 7.6 7.5 12 5.8 7.5 1.9 1 1 0 1 1 1 0 rRNA biogenesis protein RRP36 FliT PF05400.13 KIY61936.1 - 8.8 7.2 11.4 81 4.1 6.3 3.8 2 1 1 3 3 3 0 Flagellar protein FliT Prefoldin_2 PF01920.20 KIY61937.1 - 1e-22 80.1 2.4 1.2e-22 79.9 2.4 1.1 1 0 0 1 1 1 1 Prefoldin subunit Spc24 PF08286.11 KIY61937.1 - 0.0026 18.0 3.4 0.25 11.6 0.3 2.2 2 0 0 2 2 2 2 Spc24 subunit of Ndc80 DUF5082 PF16888.5 KIY61937.1 - 0.0063 16.8 1.5 1.2 9.4 0.2 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF5082) Snf7 PF03357.21 KIY61937.1 - 0.0078 15.8 2.1 0.059 13.0 0.6 2.1 2 0 0 2 2 2 1 Snf7 HMMR_C PF15908.5 KIY61937.1 - 0.023 15.0 1.8 0.03 14.6 1.8 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor C-terminal FlaC_arch PF05377.11 KIY61937.1 - 0.028 14.8 1.5 0.74 10.2 0.1 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) FliD_C PF07195.12 KIY61937.1 - 0.033 13.6 1.3 0.076 12.4 1.3 1.6 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus NPV_P10 PF05531.12 KIY61937.1 - 0.039 14.4 1.7 7.8 7.1 0.3 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein FlxA PF14282.6 KIY61937.1 - 0.11 12.6 3.1 4.1 7.4 0.4 2.2 2 0 0 2 2 2 0 FlxA-like protein Prefoldin PF02996.17 KIY61937.1 - 0.11 12.4 2.6 6.3 6.7 0.5 2.1 1 1 1 2 2 2 0 Prefoldin subunit bZIP_1 PF00170.21 KIY61937.1 - 0.16 12.1 3.2 2 8.6 0.1 2.2 2 0 0 2 2 2 0 bZIP transcription factor TBK1_ULD PF18396.1 KIY61938.1 - 0.021 14.8 0.0 0.047 13.6 0.0 1.6 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain CxC2 PF18803.1 KIY61940.1 - 2e-23 82.6 0.0 6.2e-23 81.0 0.0 1.9 2 0 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases KDZ PF18758.1 KIY61940.1 - 6.3e-23 81.5 0.1 9.3e-23 81.0 0.1 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase zinc_ribbon_9 PF14369.6 KIY61940.1 - 0.016 15.4 1.3 5.3 7.4 0.0 3.3 2 0 0 2 2 2 0 zinc-ribbon 2OG-FeII_Oxy_3 PF13640.6 KIY61941.1 - 0.0009 20.1 0.0 0.0016 19.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Tet_JBP PF12851.7 KIY61941.1 - 0.15 11.4 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Oxygenase domain of the 2OGFeDO superfamily Velvet PF11754.8 KIY61943.1 - 6.2e-21 75.5 0.1 1.6e-12 47.9 0.1 2.2 1 1 1 2 2 2 2 Velvet factor TSNAXIP1_N PF15739.5 KIY61944.1 - 0.74 10.2 6.1 0.11 12.9 1.1 1.9 2 0 0 2 2 2 0 Translin-associated factor X-interacting N-terminus Atg14 PF10186.9 KIY61944.1 - 1.3 8.1 7.2 1.7 7.7 7.2 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 F-box-like PF12937.7 KIY61945.1 - 0.00023 21.0 1.9 0.00086 19.1 1.9 2.0 1 1 0 1 1 1 1 F-box-like LRR_8 PF13855.6 KIY61945.1 - 1.1 9.1 6.4 0.33 10.8 1.3 2.7 3 1 0 3 3 3 0 Leucine rich repeat Transposase_21 PF02992.14 KIY61946.1 - 0.00012 21.4 0.0 0.0002 20.7 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 DDT PF02791.17 KIY61946.1 - 0.007 16.7 0.0 0.029 14.7 0.0 2.0 1 0 0 1 1 1 1 DDT domain DUF4218 PF13960.6 KIY61946.1 - 0.0071 15.9 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Troponin PF00992.20 KIY61949.1 - 0.00013 22.2 6.1 0.00019 21.7 6.1 1.2 1 0 0 1 1 1 1 Troponin Leu_zip PF15294.6 KIY61949.1 - 0.00035 20.2 4.3 0.00041 20.0 4.3 1.1 1 0 0 1 1 1 1 Leucine zipper DivIC PF04977.15 KIY61949.1 - 0.00093 18.9 5.8 0.3 10.9 0.4 2.3 1 1 0 2 2 2 2 Septum formation initiator GAS PF13851.6 KIY61949.1 - 0.001 18.4 7.3 0.0014 18.0 7.3 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding TMF_TATA_bd PF12325.8 KIY61949.1 - 0.002 18.3 8.2 0.35 11.1 3.6 2.1 1 1 1 2 2 2 2 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 KIY61949.1 - 0.0022 18.0 4.2 0.044 13.8 4.1 2.1 1 1 0 1 1 1 1 TATA element modulatory factor 1 DNA binding FUSC PF04632.12 KIY61949.1 - 0.0058 15.2 2.2 0.0072 14.9 2.2 1.1 1 0 0 1 1 1 1 Fusaric acid resistance protein family HAP1_N PF04849.13 KIY61949.1 - 0.0062 15.8 3.9 0.009 15.2 3.9 1.2 1 0 0 1 1 1 1 HAP1 N-terminal conserved region HMMR_N PF15905.5 KIY61949.1 - 0.0099 15.4 4.3 0.013 15.0 4.3 1.1 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal DUF4795 PF16043.5 KIY61949.1 - 0.015 14.9 5.2 0.021 14.4 5.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) DUF4618 PF15397.6 KIY61949.1 - 0.036 13.5 5.0 0.047 13.1 0.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) Syntaxin_2 PF14523.6 KIY61949.1 - 0.051 14.0 3.5 1.5 9.2 1.3 2.2 1 1 1 2 2 2 0 Syntaxin-like protein TPR_MLP1_2 PF07926.12 KIY61949.1 - 0.076 13.1 9.0 0.11 12.6 9.0 1.2 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Fez1 PF06818.15 KIY61949.1 - 0.081 13.4 4.7 0.099 13.1 4.7 1.1 1 0 0 1 1 1 0 Fez1 Fucokinase PF07959.12 KIY61949.1 - 0.092 11.7 0.1 0.11 11.4 0.1 1.1 1 0 0 1 1 1 0 L-fucokinase UPF0242 PF06785.11 KIY61949.1 - 0.1 12.7 3.3 0.13 12.3 3.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4200 PF13863.6 KIY61949.1 - 0.12 12.8 8.7 0.28 11.6 8.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) FlxA PF14282.6 KIY61949.1 - 0.13 12.2 5.7 0.24 11.4 2.5 2.5 1 1 1 2 2 2 0 FlxA-like protein DUF2680 PF10925.8 KIY61949.1 - 0.19 11.7 1.3 0.32 11.0 0.2 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2680) Phlebovirus_NSM PF07246.11 KIY61949.1 - 0.21 10.9 5.3 1.4 8.2 5.3 1.8 1 1 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Tup_N PF08581.10 KIY61949.1 - 0.24 11.7 4.5 0.19 12.1 1.3 2.0 1 1 0 2 2 2 0 Tup N-terminal Csm1_N PF18504.1 KIY61949.1 - 0.26 11.7 5.4 4.6 7.7 0.8 2.3 1 1 1 2 2 2 0 Csm1 N-terminal domain Spc7 PF08317.11 KIY61949.1 - 0.35 9.7 7.4 0.45 9.3 7.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Lin-8 PF03353.15 KIY61949.1 - 0.4 10.2 6.2 0.51 9.8 6.2 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist YabA PF06156.13 KIY61949.1 - 0.51 11.0 3.7 3.7 8.2 1.4 2.2 1 1 1 2 2 2 0 Initiation control protein YabA XhlA PF10779.9 KIY61949.1 - 0.51 10.6 2.3 1.3 9.3 0.4 2.1 2 0 0 2 2 2 0 Haemolysin XhlA DUF724 PF05266.14 KIY61949.1 - 0.84 9.4 7.1 1.2 9.0 7.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) ZapB PF06005.12 KIY61949.1 - 0.87 10.1 6.0 34 5.0 6.0 2.5 1 1 0 1 1 1 0 Cell division protein ZapB SlyX PF04102.12 KIY61949.1 - 1 10.0 6.0 7.3 7.3 2.8 2.8 1 1 1 2 2 2 0 SlyX PRKG1_interact PF15898.5 KIY61949.1 - 1.2 10.1 9.0 1.4 9.9 1.2 2.5 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain APG6_N PF17675.1 KIY61949.1 - 2.1 8.9 8.9 13 6.3 9.1 1.9 1 1 0 1 1 1 0 Apg6 coiled-coil region CENP-H PF05837.12 KIY61949.1 - 2.6 8.5 8.3 4.1 7.9 3.7 2.1 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Velvet PF11754.8 KIY61950.1 - 1.2e-19 71.3 0.2 3.5e-11 43.5 0.1 2.1 1 1 1 2 2 2 2 Velvet factor CysG_dimeriser PF10414.9 KIY61950.1 - 0.15 11.8 0.4 0.24 11.2 0.4 1.3 1 0 0 1 1 1 0 Sirohaem synthase dimerisation region RVP_2 PF08284.11 KIY61951.1 - 1.3e-06 28.2 0.0 1.9e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 KIY61951.1 - 0.0011 19.4 0.0 0.003 18.1 0.0 1.7 2 1 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KIY61951.1 - 0.0048 17.5 0.0 0.011 16.3 0.0 1.9 1 1 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 KIY61951.1 - 0.027 14.2 0.0 0.043 13.6 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease Integrase_H2C2 PF17921.1 KIY61952.1 - 7.3e-07 29.2 0.2 9.3e-07 28.9 0.2 1.2 1 0 0 1 1 1 1 Integrase zinc binding domain API5 PF05918.11 KIY61956.1 - 0.61 8.8 2.4 0.93 8.2 2.4 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) CAP_N PF01213.19 KIY61957.1 - 9.8 5.6 5.2 13 5.2 5.2 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Cauli_VI PF01693.16 KIY61958.1 - 3.2e-18 65.8 7.7 8e-09 35.7 1.4 2.3 2 0 0 2 2 2 2 Caulimovirus viroplasmin Nitrophorin PF02087.15 KIY61962.1 - 0.21 11.5 0.0 0.29 11.1 0.0 1.2 1 0 0 1 1 1 0 Nitrophorin KDZ PF18758.1 KIY61963.1 - 9.2e-44 149.7 0.0 4.4e-43 147.5 0.0 1.9 2 0 0 2 2 2 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KIY61963.1 - 6e-32 110.0 0.0 1.3e-31 108.9 0.0 1.6 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KIY61963.1 - 4.1e-06 26.9 0.0 1.4e-05 25.2 0.0 1.9 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases HEPN_AbiU2 PF18734.1 KIY61963.1 - 0.045 13.3 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 AbiU2 Methyltransf_29 PF03141.16 KIY61964.1 - 0.17 10.4 0.0 0.19 10.2 0.0 1.0 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Vps36_ESCRT-II PF11605.8 KIY61965.1 - 0.085 13.0 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 DUF4250 PF14056.6 KIY61967.1 - 0.26 11.3 0.2 0.26 11.3 0.2 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4250) PHA_gran_rgn PF09650.10 KIY61967.1 - 7.2 7.0 10.3 1.4 9.2 1.9 3.3 3 1 1 4 4 4 0 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) Zn_clus PF00172.18 KIY61968.1 - 1.1e-06 28.6 7.9 2.3e-06 27.6 7.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 KIY61970.1 - 6.3e-07 29.4 10.0 1.1e-06 28.7 10.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cofilin_ADF PF00241.20 KIY61971.1 - 2.6e-33 114.4 0.0 9.1e-18 64.2 0.0 2.2 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein Pkinase PF00069.25 KIY61972.1 - 6e-22 78.3 0.0 8.1e-22 77.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KIY61972.1 - 5.8e-09 35.2 0.1 7.9e-09 34.8 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 KIY61972.1 - 5.4e-08 32.4 0.1 2.9e-07 30.1 0.1 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KIY61972.1 - 0.025 13.9 0.0 0.043 13.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIY61972.1 - 0.028 14.3 0.0 0.069 13.1 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family KDZ PF18758.1 KIY61974.1 - 2.3e-44 151.6 0.0 7.9e-44 149.9 0.0 1.9 2 0 0 2 2 2 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KIY61974.1 - 2.2e-30 104.9 0.1 5.7e-30 103.6 0.1 1.8 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KIY61974.1 - 1.2e-05 25.4 0.0 3.5e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases HEPN_AbiU2 PF18734.1 KIY61974.1 - 0.013 15.0 0.0 0.031 13.8 0.0 1.5 1 0 0 1 1 1 0 AbiU2 Cauli_VI PF01693.16 KIY61979.1 - 3.6e-17 62.4 5.6 3.4e-08 33.6 0.3 2.6 3 0 0 3 3 3 2 Caulimovirus viroplasmin API5 PF05918.11 KIY61981.1 - 0.63 8.8 2.8 1.1 8.0 2.8 1.3 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) FtsL PF04999.13 KIY61982.1 - 8.5 6.5 7.3 8.6 6.4 0.1 2.5 3 0 0 3 3 3 0 Cell division protein FtsL FtsL PF04999.13 KIY61990.1 - 0.0066 16.4 1.3 1.3 9.1 0.1 2.3 2 0 0 2 2 2 2 Cell division protein FtsL F-box-like PF12937.7 KIY61991.1 - 1.5e-09 37.6 0.9 3.9e-09 36.3 0.9 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY61991.1 - 0.1 12.5 2.0 4.6 7.3 0.2 2.9 2 0 0 2 2 2 0 F-box domain LRR_4 PF12799.7 KIY61991.1 - 0.14 12.7 8.6 33 5.1 0.3 5.0 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) SepSecS PF05889.13 KIY61992.1 - 0.15 10.7 0.0 0.34 9.5 0.0 1.5 2 0 0 2 2 2 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS BTB PF00651.31 KIY61995.1 - 0.059 13.6 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 BTB/POZ domain Ric8 PF10165.9 KIY61996.1 - 4.6e-113 378.7 0.0 5.6e-113 378.4 0.0 1.1 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn DUF1400 PF07176.11 KIY61996.1 - 0.087 13.1 0.1 0.2 11.9 0.1 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1400) Peptidase_C48 PF02902.19 KIY61999.1 - 7.2e-08 32.5 0.2 1.7e-07 31.3 0.2 1.6 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain tRNA_anti-codon PF01336.25 KIY62000.1 - 0.0016 18.4 0.0 0.003 17.5 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain GRAM PF02893.20 KIY62002.1 - 0.00012 22.0 0.0 0.00045 20.1 0.0 1.7 1 1 1 2 2 2 1 GRAM domain PH_TFIIH PF08567.11 KIY62002.1 - 0.2 12.0 0.0 0.34 11.3 0.0 1.3 1 0 0 1 1 1 0 TFIIH p62 subunit, N-terminal domain DUF202 PF02656.15 KIY62003.1 - 4.3e-18 65.5 1.1 4.3e-18 65.5 1.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF4227 PF14004.6 KIY62003.1 - 0.011 15.7 0.8 9.2 6.3 0.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF4227) DUF2919 PF11143.8 KIY62003.1 - 0.05 13.9 1.3 0.14 12.5 0.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2919) S_4TM PF18159.1 KIY62003.1 - 0.13 11.5 4.1 0.043 13.1 1.1 1.6 1 1 1 2 2 2 0 SMODS-associating 4TM effector domain RasGAP PF00616.19 KIY62004.1 - 1.5e-21 77.1 0.0 2.6e-14 53.4 0.0 2.8 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase MOR2-PAG1_C PF14225.6 KIY62004.1 - 3.5e-05 23.8 0.4 0.00052 20.0 0.1 2.9 2 0 0 2 2 2 1 Cell morphogenesis C-terminal CRAL_TRIO_2 PF13716.6 KIY62004.1 - 0.0017 18.5 0.0 0.0045 17.2 0.0 1.7 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain RRP7 PF12923.7 KIY62005.1 - 2.1e-26 92.4 5.9 2.1e-26 92.4 5.9 1.8 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RRM_Rrp7 PF17799.1 KIY62005.1 - 2.3e-10 40.5 0.0 8.3e-10 38.7 0.0 2.0 2 1 0 2 2 2 1 Rrp7 RRM-like N-terminal domain RRM_1 PF00076.22 KIY62005.1 - 0.00018 21.3 0.0 0.00041 20.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RGS PF00615.19 KIY62006.1 - 2.3e-09 37.6 0.0 4.6e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Regulator of G protein signaling domain Glyco_hydro_cc PF11790.8 KIY62007.1 - 7.4e-65 218.8 4.6 8.9e-65 218.6 4.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core HNH_2 PF13391.6 KIY62008.1 - 0.015 15.4 0.0 0.04 14.1 0.0 1.7 1 0 0 1 1 1 0 HNH endonuclease Reticulon PF02453.17 KIY62008.1 - 0.06 13.3 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Reticulon CBM_20 PF00686.19 KIY62009.1 - 4e-31 106.8 0.7 8.6e-31 105.7 0.7 1.6 1 0 0 1 1 1 1 Starch binding domain Alpha-amylase PF00128.24 KIY62009.1 - 2.3e-15 57.0 0.0 3.1e-13 50.0 0.0 2.2 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.18 KIY62009.1 - 1.1e-11 45.0 0.2 3.8e-11 43.3 0.1 2.0 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain Jacalin PF01419.17 KIY62010.1 - 0.00019 21.4 0.0 0.0003 20.7 0.0 1.2 1 0 0 1 1 1 1 Jacalin-like lectin domain TMF_DNA_bd PF12329.8 KIY62010.1 - 0.0019 18.2 1.4 0.0036 17.3 1.4 1.4 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding ADIP PF11559.8 KIY62010.1 - 0.0043 17.2 1.4 0.0064 16.6 1.4 1.3 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding bZIP_1 PF00170.21 KIY62010.1 - 0.019 15.1 0.8 0.041 14.0 0.8 1.5 1 0 0 1 1 1 0 bZIP transcription factor DUF4201 PF13870.6 KIY62010.1 - 0.024 14.3 0.2 0.039 13.7 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) ZapB PF06005.12 KIY62010.1 - 0.026 14.9 0.2 0.052 14.0 0.2 1.4 1 0 0 1 1 1 0 Cell division protein ZapB Cast PF10174.9 KIY62010.1 - 0.032 12.5 0.6 0.041 12.1 0.6 1.1 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone DivIC PF04977.15 KIY62010.1 - 0.062 13.1 0.7 0.11 12.2 0.7 1.4 1 0 0 1 1 1 0 Septum formation initiator Spc29 PF17082.5 KIY62010.1 - 0.075 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Spindle Pole Component 29 HALZ PF02183.18 KIY62010.1 - 1.6 9.0 6.6 0.12 12.6 1.7 1.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper HIP1_clath_bdg PF16515.5 KIY62011.1 - 0.0019 18.8 1.4 0.0019 18.8 1.4 3.2 1 1 2 3 3 3 1 Clathrin-binding domain of Huntingtin-interacting protein 1 Sec3_C_2 PF15278.6 KIY62011.1 - 0.019 15.3 1.2 0.019 15.3 1.2 2.3 2 2 0 2 2 2 0 Sec3 exocyst complex subunit FH2 PF02181.23 KIY62011.1 - 0.32 10.0 5.0 0.071 12.2 1.7 1.6 2 0 0 2 2 2 0 Formin Homology 2 Domain DUF1664 PF07889.12 KIY62011.1 - 0.78 9.8 5.5 1.4 8.9 0.6 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Filament PF00038.21 KIY62011.1 - 0.82 9.2 12.2 0.46 10.0 4.3 2.7 1 1 2 3 3 3 0 Intermediate filament protein SKA2 PF16740.5 KIY62011.1 - 1.1 9.0 9.3 0.36 10.6 0.6 2.7 2 1 1 3 3 3 0 Spindle and kinetochore-associated protein 2 DUF3818 PF12825.7 KIY62011.1 - 1.3 8.0 5.1 0.71 8.8 1.8 1.8 1 1 1 2 2 2 0 Domain of unknown function in PX-proteins (DUF3818) zf-CCHC PF00098.23 KIY62012.1 - 8.2e-13 47.8 28.2 4.1e-05 23.5 2.0 4.3 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_2 PF13696.6 KIY62012.1 - 0.00026 20.7 2.7 0.0073 16.1 0.3 4.4 4 1 1 5 5 5 2 Zinc knuckle NPR3 PF03666.13 KIY62012.1 - 0.25 10.1 6.1 0.29 9.9 6.1 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CDC45 PF02724.14 KIY62012.1 - 3.2 5.9 8.8 4 5.6 8.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Zip PF02535.22 KIY62012.1 - 4.2 6.5 3.7 4.9 6.3 3.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter zf-CCHC_4 PF14392.6 KIY62012.1 - 5.1 6.9 25.3 1.3 8.8 0.5 4.3 4 0 0 4 4 4 0 Zinc knuckle zf-CCHC_5 PF14787.6 KIY62012.1 - 7.9 6.3 25.9 1.8 8.3 0.9 4.7 3 1 1 4 4 4 0 GAG-polyprotein viral zinc-finger Exo_endo_phos PF03372.23 KIY62013.1 - 1.4e-19 70.5 1.4 1.7e-18 67.0 1.4 2.1 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_8 PF13855.6 KIY62013.1 - 3.5e-14 52.3 5.1 2.5e-09 36.8 0.5 2.4 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KIY62013.1 - 7.3e-12 45.3 4.0 3.7e-05 24.0 0.2 2.9 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KIY62013.1 - 0.00029 21.0 1.5 0.64 10.8 0.3 4.2 3 1 1 4 4 4 1 Leucine Rich Repeat LRR_6 PF13516.6 KIY62013.1 - 0.48 10.6 6.5 8.3 6.7 0.4 3.4 3 0 0 3 3 3 0 Leucine Rich repeat DUF4110 PF13422.6 KIY62016.1 - 0.13 12.3 0.1 0.57 10.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4110) Mitofilin PF09731.9 KIY62021.1 - 5e-40 138.0 25.5 1.1e-38 133.6 25.5 2.0 1 1 0 1 1 1 1 Mitochondrial inner membrane protein Apolipoprotein PF01442.18 KIY62021.1 - 0.014 15.2 20.6 0.023 14.6 2.5 2.9 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain DUF2894 PF11445.8 KIY62021.1 - 0.043 14.3 12.2 0.99 9.9 1.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2894) DUF1978 PF09321.10 KIY62021.1 - 1.2 8.3 18.4 0.065 12.5 11.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1978) PMEI PF04043.15 KIY62021.1 - 7.6 6.9 8.7 8 6.8 3.9 2.3 2 0 0 2 2 2 0 Plant invertase/pectin methylesterase inhibitor ATG22 PF11700.8 KIY62022.1 - 1.3e-126 423.0 20.9 1.5e-126 422.8 20.9 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like Trp_oprn_chp PF09534.10 KIY62022.1 - 0.28 11.0 3.2 2.8 7.7 0.0 3.2 3 1 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF2157 PF09925.9 KIY62022.1 - 2.3 8.0 26.2 1.5 8.6 5.1 3.8 2 1 1 3 3 3 0 Predicted membrane protein (DUF2157) TssN PF17555.2 KIY62022.1 - 3.3 7.0 15.8 0.2 11.0 7.9 2.4 1 1 1 2 2 2 0 Type VI secretion system, TssN DUF2456 PF10445.9 KIY62022.1 - 6.7 6.9 11.3 4.5 7.4 7.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2456) UBA2_C PF16195.5 KIY62023.1 - 0.019 15.6 0.1 0.035 14.8 0.1 1.4 1 0 0 1 1 1 0 SUMO-activating enzyme subunit 2 C-terminus NIF PF03031.18 KIY62024.1 - 1.9e-13 50.5 0.0 3.6e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Metal_resist PF13801.6 KIY62024.1 - 0.011 16.0 4.3 0.04 14.1 4.3 2.0 1 0 0 1 1 1 0 Heavy-metal resistance Pkinase PF00069.25 KIY62025.1 - 3e-59 200.5 0.0 3.8e-59 200.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY62025.1 - 4.4e-30 104.8 0.0 5.4e-30 104.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY62025.1 - 5e-09 35.9 0.0 8.5e-09 35.1 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 KIY62025.1 - 0.004 16.5 0.1 0.019 14.3 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KIY62025.1 - 0.0079 15.2 0.0 0.012 14.5 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KIY62025.1 - 0.021 14.7 0.0 0.058 13.3 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Arrestin_C PF02752.22 KIY62026.1 - 0.00062 20.2 0.0 0.041 14.3 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KIY62026.1 - 0.045 13.8 0.0 0.85 9.7 0.0 2.6 1 1 1 2 2 2 0 Arrestin (or S-antigen), N-terminal domain Methyltransf_16 PF10294.9 KIY62027.1 - 1.3e-19 70.6 0.0 1.8e-19 70.2 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Mito_carr PF00153.27 KIY62028.1 - 6.2e-59 195.9 2.0 2.4e-22 78.6 0.6 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein TNT PF14021.6 KIY62029.1 - 1.9e-31 108.5 0.0 2.1e-31 108.3 0.0 1.0 1 0 0 1 1 1 1 Tuberculosis necrotizing toxin MIF4G_like_2 PF09090.11 KIY62030.1 - 0.25 10.8 4.2 0.51 9.8 4.2 1.5 1 0 0 1 1 1 0 MIF4G like Casc1_N PF15927.5 KIY62030.1 - 2.1 8.0 13.9 3.8 7.1 13.9 1.4 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus Gln-synt_C PF00120.24 KIY62031.1 - 0.21 10.6 0.2 0.33 9.9 0.2 1.2 1 0 0 1 1 1 0 Glutamine synthetase, catalytic domain Shikimate_dh_N PF08501.11 KIY62032.1 - 2.7e-18 66.0 0.0 6.2e-18 64.8 0.0 1.7 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain WD40 PF00400.32 KIY62036.1 - 7e-59 194.4 32.2 6.8e-08 33.1 0.1 8.9 8 1 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY62036.1 - 3.5e-20 72.1 2.0 0.0028 17.9 0.0 5.4 3 2 2 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain NLE PF08154.12 KIY62036.1 - 2.8e-10 40.5 0.1 5.6e-10 39.6 0.1 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.8 KIY62036.1 - 1.8e-05 23.6 6.2 0.032 12.9 0.7 4.0 2 1 1 4 4 4 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KIY62036.1 - 0.0001 21.4 0.0 0.7 8.8 0.0 3.3 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 KIY62036.1 - 0.00039 19.3 0.4 0.96 8.1 0.0 3.4 3 1 1 4 4 4 2 Nup133 N terminal like IKI3 PF04762.12 KIY62036.1 - 0.03 12.3 0.0 0.052 11.5 0.0 1.3 1 0 0 1 1 1 0 IKI3 family Frtz PF11768.8 KIY62036.1 - 0.23 9.7 0.0 2.5 6.3 0.0 2.1 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz PQQ_3 PF13570.6 KIY62036.1 - 0.32 11.6 1.9 19 5.9 0.0 3.6 3 1 0 3 3 3 0 PQQ-like domain PD40 PF07676.12 KIY62036.1 - 0.33 11.0 2.2 2.9 7.9 0.2 3.2 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat YqfD PF06898.11 KIY62041.1 - 4 6.2 4.7 0.79 8.5 1.0 1.6 2 0 0 2 2 2 0 Putative stage IV sporulation protein YqfD HrpB_C PF08482.10 KIY62042.1 - 0.09 13.2 0.0 0.12 12.8 0.0 1.2 1 0 0 1 1 1 0 ATP-dependent helicase C-terminal CBM_5_12 PF02839.14 KIY62043.1 - 0.00041 20.8 5.6 0.0014 19.1 5.6 1.9 1 0 0 1 1 1 1 Carbohydrate binding domain DPBB_1 PF03330.18 KIY62043.1 - 0.0016 18.7 0.3 0.0038 17.5 0.3 1.7 1 1 0 1 1 1 1 Lytic transglycolase Cerato-platanin PF07249.12 KIY62043.1 - 0.0041 17.2 1.1 0.011 15.8 0.1 2.1 2 1 0 2 2 2 1 Cerato-platanin CBM_5_12_2 PF14600.6 KIY62043.1 - 0.09 12.7 4.5 0.12 12.3 3.0 2.1 2 0 0 2 2 2 0 Cellulose-binding domain Glyco_hydro_7 PF00840.20 KIY62046.1 - 9.5e-210 696.8 16.2 1.1e-209 696.6 16.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Thi4 PF01946.17 KIY62047.1 - 1.7e-101 338.4 0.1 2e-101 338.1 0.1 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 KIY62047.1 - 4.3e-10 39.7 4.0 2.6e-09 37.1 0.9 2.1 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIY62047.1 - 1.3e-07 31.1 0.1 1.8e-07 30.7 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KIY62047.1 - 1.6e-07 30.7 0.8 1.4e-06 27.6 0.2 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KIY62047.1 - 2.3e-06 27.7 0.2 5.9e-06 26.4 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KIY62047.1 - 4.5e-06 26.0 2.0 4.9e-05 22.6 0.4 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 KIY62047.1 - 1.6e-05 24.9 3.3 9e-05 22.5 0.1 2.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding HI0933_like PF03486.14 KIY62047.1 - 0.00014 20.7 0.2 0.00024 20.0 0.2 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.7 KIY62047.1 - 0.00032 20.2 0.5 0.00046 19.7 0.5 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 KIY62047.1 - 0.012 14.8 0.9 0.024 13.7 0.6 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A Trp_halogenase PF04820.14 KIY62047.1 - 0.012 14.5 0.1 0.018 13.9 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_3 PF13738.6 KIY62047.1 - 0.035 13.4 0.2 0.099 11.9 0.1 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KIY62047.1 - 0.036 13.4 0.0 0.052 12.8 0.0 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 KIY62047.1 - 0.046 14.3 0.1 0.11 13.0 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KIY62047.1 - 0.14 11.3 0.1 0.33 10.0 0.0 1.7 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Pro_isomerase PF00160.21 KIY62048.1 - 2.2e-50 171.0 0.4 4.6e-50 170.0 0.2 1.7 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 KIY62048.1 - 1e-11 45.1 0.6 8.2e-05 23.3 0.0 4.8 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY62048.1 - 0.0079 16.5 0.0 0.056 13.8 0.0 2.4 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIY62048.1 - 0.061 12.3 0.1 0.18 10.7 0.0 1.8 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein XPC-binding PF09280.11 KIY62050.1 - 0.097 12.4 0.1 0.32 10.7 0.0 1.9 2 0 0 2 2 2 0 XPC-binding domain Kei1 PF08552.11 KIY62051.1 - 0.0014 18.5 0.4 0.0021 18.0 0.2 1.3 1 1 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 Tetraspanin PF00335.20 KIY62051.1 - 0.058 13.1 0.1 0.19 11.4 0.0 1.4 1 1 0 1 1 1 0 Tetraspanin family MacB_PCD PF12704.7 KIY62052.1 - 0.03 14.7 0.0 0.036 14.4 0.0 1.1 1 0 0 1 1 1 0 MacB-like periplasmic core domain Tetraspanin PF00335.20 KIY62052.1 - 0.04 13.6 1.3 0.06 13.0 1.3 1.2 1 0 0 1 1 1 0 Tetraspanin family BA14K PF07886.11 KIY62055.1 - 0.052 13.4 0.0 0.14 12.1 0.0 1.8 1 0 0 1 1 1 0 BA14K-like protein Hydin_ADK PF17213.3 KIY62057.1 - 1.8 8.8 6.6 5 7.3 6.6 1.7 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain K-box PF01486.17 KIY62058.1 - 0.14 12.3 0.1 0.23 11.7 0.1 1.3 1 0 0 1 1 1 0 K-box region KDZ PF18758.1 KIY62059.1 - 1.4e-54 185.1 3.3 4.3e-53 180.2 1.6 3.0 3 0 0 3 3 3 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KIY62059.1 - 1.4e-30 105.6 0.0 9.2e-30 103.0 0.0 2.2 2 0 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KIY62059.1 - 6.9e-05 22.9 0.0 0.00029 21.0 0.0 2.0 2 0 0 2 2 2 1 CxC1 like cysteine cluster associated with KDZ transposases zf-UBR PF02207.20 KIY62059.1 - 0.018 15.2 3.8 0.068 13.3 3.8 2.1 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) AAL_decarboxy PF03306.13 KIY62061.1 - 0.12 11.7 0.1 0.31 10.3 0.0 1.6 2 0 0 2 2 2 0 Alpha-acetolactate decarboxylase DUF5548 PF17702.1 KIY62063.1 - 0.072 12.8 0.1 0.18 11.5 0.1 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5548) YL1 PF05764.13 KIY62063.1 - 0.61 10.2 8.9 0.95 9.5 8.9 1.3 1 0 0 1 1 1 0 YL1 nuclear protein DNA_pol_phi PF04931.13 KIY62063.1 - 8.7 4.3 6.0 14 3.7 6.0 1.2 1 0 0 1 1 1 0 DNA polymerase phi Pkinase PF00069.25 KIY62065.1 - 2e-42 145.4 0.0 2.5e-42 145.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY62065.1 - 3.6e-17 62.5 0.0 4.7e-17 62.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY62065.1 - 3.7e-09 36.3 0.0 7.5e-08 32.0 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KIY62065.1 - 0.00011 22.2 0.1 0.18 11.7 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KIY62065.1 - 0.0012 18.2 0.0 0.0019 17.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KIY62065.1 - 0.013 14.5 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain WD40_alt PF14077.6 KIY62065.1 - 0.16 11.9 0.0 0.38 10.6 0.0 1.6 1 0 0 1 1 1 0 Alternative WD40 repeat motif RIO1 PF01163.22 KIY62065.1 - 0.21 11.2 0.0 0.33 10.5 0.0 1.3 1 0 0 1 1 1 0 RIO1 family IBR PF01485.21 KIY62067.1 - 2e-11 43.9 48.4 2.7e-06 27.5 13.4 4.5 4 0 0 4 4 4 4 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 KIY62067.1 - 0.0043 17.4 6.2 0.0043 17.4 6.2 5.1 4 2 1 5 5 5 1 Ring finger domain MoaE PF02391.17 KIY62067.1 - 0.13 12.6 0.0 0.26 11.6 0.0 1.5 1 0 0 1 1 1 0 MoaE protein 3HCDH_N PF02737.18 KIY62069.1 - 4.3e-50 170.1 2.0 2.3e-49 167.7 2.0 1.9 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KIY62069.1 - 6.6e-32 110.0 0.0 1.3e-31 109.0 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KIY62069.1 - 0.024 14.8 0.1 0.048 13.8 0.1 1.5 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Glyco_hydro_71 PF03659.14 KIY62070.1 - 1.1e-94 317.3 13.7 1.1e-94 317.3 13.7 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 71 WSC PF01822.19 KIY62070.1 - 1.1e-43 147.3 65.9 1.4e-15 57.2 13.2 4.6 4 1 0 4 4 4 3 WSC domain RNA_pol_N PF01194.17 KIY62072.1 - 1.5e-31 108.5 0.4 1.9e-31 108.1 0.4 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.12 KIY62072.1 - 0.028 14.7 0.4 0.036 14.3 0.4 1.2 1 0 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) Transposase_31 PF04754.12 KIY62072.1 - 0.061 12.9 0.0 0.069 12.7 0.0 1.1 1 0 0 1 1 1 0 Putative transposase, YhgA-like Gly_transf_sug PF04488.15 KIY62073.1 - 4.4e-05 24.0 0.0 0.0001 22.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif ANAPC4_WD40 PF12894.7 KIY62074.1 - 1.1e-15 57.6 3.5 0.00015 22.0 0.0 4.1 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KIY62074.1 - 4.2e-14 52.7 13.5 1.4e-05 25.7 0.1 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat eIF2A PF08662.11 KIY62074.1 - 0.00042 20.2 0.0 0.086 12.7 0.0 3.1 1 1 2 3 3 3 1 Eukaryotic translation initiation factor eIF2A Kelch_6 PF13964.6 KIY62074.1 - 0.032 14.5 0.5 3.7 8.0 0.0 3.7 3 0 0 3 3 3 0 Kelch motif DUF3390 PF11870.8 KIY62076.1 - 0.056 13.8 0.5 0.12 12.8 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3390) Pap_E4 PF02711.14 KIY62076.1 - 1.4 9.9 5.0 0.32 12.0 1.6 1.7 2 0 0 2 2 2 0 E4 protein Pkinase PF00069.25 KIY62077.1 - 3e-56 190.7 0.0 4.1e-56 190.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY62077.1 - 7.6e-24 84.4 0.0 1.1e-23 83.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY62077.1 - 2e-05 24.1 0.1 6.1e-05 22.5 0.1 1.8 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 KIY62077.1 - 0.042 13.2 0.0 0.078 12.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KIY62077.1 - 0.15 11.7 0.0 18 4.9 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF3390 PF11870.8 KIY62078.1 - 0.059 13.8 0.4 0.11 12.8 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3390) Pap_E4 PF02711.14 KIY62078.1 - 3.6 8.6 7.1 0.3 12.1 1.8 1.8 2 0 0 2 2 2 0 E4 protein PrkA PF06798.12 KIY62082.1 - 0.0048 16.6 1.3 0.0059 16.3 1.3 1.2 1 0 0 1 1 1 1 PrkA serine protein kinase C-terminal domain BAG6 PF12057.8 KIY62082.1 - 0.11 12.1 1.8 0.22 11.2 0.2 2.1 1 1 2 3 3 3 0 BCL2-associated athanogene 6 SelB-wing_1 PF09105.10 KIY62083.1 - 0.058 13.4 0.1 0.12 12.4 0.0 1.6 2 0 0 2 2 2 0 Elongation factor SelB, winged helix F-box-like PF12937.7 KIY62085.1 - 0.00072 19.4 0.8 0.0016 18.3 0.0 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIY62085.1 - 0.016 15.1 0.0 0.12 12.3 0.0 2.4 2 0 0 2 2 2 0 F-box domain LRR_4 PF12799.7 KIY62085.1 - 1.7 9.2 8.4 14 6.2 0.1 5.9 6 2 2 8 8 8 0 Leucine Rich repeats (2 copies) DUF829 PF05705.14 KIY62086.1 - 5.5e-35 121.4 0.7 1.2e-33 117.0 0.7 2.0 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) MMgT PF10270.9 KIY62087.1 - 2.7e-17 62.9 0.0 3.3e-17 62.7 0.0 1.1 1 0 0 1 1 1 1 Membrane magnesium transporter Zw10 PF06248.13 KIY62088.1 - 2.2e-21 76.1 0.0 3e-19 69.0 0.0 2.5 2 1 0 2 2 2 2 Centromere/kinetochore Zw10 Dsl1_C PF11989.8 KIY62088.1 - 5.4e-07 29.5 1.3 7.1e-07 29.1 0.2 1.7 2 0 0 2 2 2 1 Retrograde transport protein Dsl1 C terminal ApoLp-III PF07464.11 KIY62088.1 - 0.0052 16.9 0.7 0.014 15.5 0.7 1.7 1 0 0 1 1 1 1 Apolipophorin-III precursor (apoLp-III) MMR_HSR1 PF01926.23 KIY62089.1 - 4.6e-17 62.2 0.4 2.3e-14 53.5 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 KIY62089.1 - 9.1e-09 35.0 0.2 4.6e-06 26.3 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KIY62089.1 - 6.1e-06 26.2 0.0 1.6e-05 24.9 0.0 1.7 1 1 0 1 1 1 1 RsgA GTPase Dynamin_N PF00350.23 KIY62089.1 - 0.0014 18.7 2.1 0.47 10.5 0.1 3.0 2 1 1 3 3 3 2 Dynamin family GTP_EFTU PF00009.27 KIY62089.1 - 0.0037 16.8 0.2 0.045 13.3 0.0 2.4 1 1 1 3 3 3 1 Elongation factor Tu GTP binding domain MeaB PF03308.16 KIY62089.1 - 0.004 16.2 0.1 0.0085 15.1 0.1 1.5 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 KIY62089.1 - 0.012 16.2 0.1 0.14 12.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KIY62089.1 - 0.041 14.3 0.5 1.4 9.3 0.0 2.7 2 1 0 2 2 2 0 AAA ATPase domain cobW PF02492.19 KIY62089.1 - 0.075 12.6 0.1 0.65 9.6 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 KIY62089.1 - 0.14 12.4 0.1 16 5.7 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DUF5027 PF16430.5 KIY62089.1 - 0.16 11.7 0.0 0.81 9.4 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5027) zf-HC5HC2H_2 PF13832.6 KIY62090.1 - 1.4e-24 86.4 3.2 1.4e-24 86.4 3.2 2.3 2 0 0 2 2 2 1 PHD-zinc-finger like domain EPL1 PF10513.9 KIY62090.1 - 3.2e-21 76.3 0.0 3.2e-21 76.3 0.0 4.5 3 1 0 3 3 2 1 Enhancer of polycomb-like Bromodomain PF00439.25 KIY62090.1 - 3.9e-18 65.3 0.2 8.9e-18 64.2 0.2 1.6 1 0 0 1 1 1 1 Bromodomain zf-HC5HC2H PF13771.6 KIY62090.1 - 9.1e-15 54.7 0.4 9.1e-15 54.7 0.4 2.8 3 0 0 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.6 KIY62090.1 - 6.1e-14 51.3 3.6 1.8e-13 49.8 3.6 1.8 1 0 0 1 1 1 1 PHD-finger PHD PF00628.29 KIY62090.1 - 8.3e-10 38.4 4.3 8.3e-10 38.4 4.3 2.8 2 0 0 2 2 2 1 PHD-finger zf-PHD-like PF15446.6 KIY62090.1 - 0.0021 17.7 0.9 0.0059 16.2 0.9 1.8 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain PWWP PF00855.17 KIY62090.1 - 0.015 15.7 1.0 0.051 14.0 1.0 2.0 1 0 0 1 1 1 0 PWWP domain Zf_RING PF16744.5 KIY62090.1 - 0.033 14.3 7.5 1 9.5 0.5 2.6 2 0 0 2 2 2 0 KIAA1045 RING finger C1_1 PF00130.22 KIY62090.1 - 4.3 7.3 10.1 0.066 13.1 0.4 2.4 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_9 PF13901.6 KIY62090.1 - 7.3 6.5 9.9 0.41 10.6 0.3 2.9 3 0 0 3 3 3 0 Putative zinc-RING and/or ribbon gag-asp_proteas PF13975.6 KIY62093.1 - 0.082 13.5 0.0 0.36 11.4 0.0 2.0 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease YsaB PF13983.6 KIY62093.1 - 0.099 12.9 0.1 0.27 11.5 0.1 1.8 1 0 0 1 1 1 0 YsaB-like lipoprotein AlaDh_PNT_N PF05222.15 KIY62093.1 - 0.11 12.8 0.0 0.23 11.8 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, N-terminal domain zf-CCHC PF00098.23 KIY62094.1 - 0.0013 18.7 1.4 0.0027 17.7 1.4 1.6 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 KIY62094.1 - 0.0074 16.5 0.5 0.022 15.0 0.5 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein OTT_1508_deam PF14441.6 KIY62095.1 - 1e-06 28.6 0.0 2.2e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 OTT_1508-like deaminase Phage_int_SAM_4 PF13495.6 KIY62095.1 - 0.022 15.2 0.0 1.2 9.7 0.0 2.3 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain Cu_bind_like PF02298.17 KIY62096.1 - 0.00013 21.9 0.3 0.00043 20.2 0.3 1.9 1 0 0 1 1 1 1 Plastocyanin-like domain Pyr_redox_2 PF07992.14 KIY62098.1 - 4.8e-12 45.7 0.0 1.3e-10 41.0 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Malic_M PF03949.15 KIY62098.1 - 0.008 15.5 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain NAD_binding_9 PF13454.6 KIY62098.1 - 0.029 14.4 0.0 0.15 12.0 0.0 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding DAO PF01266.24 KIY62098.1 - 0.17 11.5 0.2 1.7 8.1 0.1 2.1 1 1 0 2 2 2 0 FAD dependent oxidoreductase RasGAP_C PF03836.15 KIY62099.1 - 0.011 15.9 3.4 0.011 15.9 3.4 1.9 1 1 1 2 2 2 0 RasGAP C-terminus DUF3552 PF12072.8 KIY62099.1 - 0.059 12.8 13.2 0.07 12.5 13.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) TLP-20 PF06088.11 KIY62099.1 - 0.15 11.9 5.4 0.29 11.0 5.4 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) CAML PF14963.6 KIY62099.1 - 0.19 11.8 2.7 0.21 11.7 2.7 1.1 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand CENP-H PF05837.12 KIY62099.1 - 0.22 11.9 12.4 0.074 13.5 1.4 2.0 1 1 1 2 2 2 0 Centromere protein H (CENP-H) FAM60A PF15396.6 KIY62099.1 - 0.6 10.1 5.7 0.77 9.7 5.7 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DUF4407 PF14362.6 KIY62099.1 - 0.65 9.3 9.4 0.75 9.1 9.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF842 PF05811.13 KIY62100.1 - 0.0026 17.4 0.5 0.0031 17.2 0.5 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) zf-H2C2_5 PF13909.6 KIY62100.1 - 0.034 13.9 0.0 0.09 12.5 0.0 1.7 1 0 0 1 1 1 0 C2H2-type zinc-finger domain PX PF00787.24 KIY62100.1 - 0.047 13.7 0.1 0.055 13.4 0.1 1.1 1 0 0 1 1 1 0 PX domain zf-C2H2 PF00096.26 KIY62100.1 - 0.33 11.5 4.4 14 6.3 2.6 2.8 2 1 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIY62100.1 - 1 10.4 6.3 2 9.5 0.0 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger DUF4519 PF15012.6 KIY62101.1 - 0.77 10.0 4.2 1.8 8.8 4.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) KDZ PF18758.1 KIY62103.1 - 9.9e-47 159.4 0.0 1.7e-46 158.6 0.0 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KIY62103.1 - 2.9e-29 101.4 1.2 8.3e-29 99.9 1.2 1.8 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KIY62103.1 - 1.2e-05 25.4 0.3 4.4e-05 23.6 0.3 1.9 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases GA-like PF17573.2 KIY62103.1 - 0.14 12.1 0.0 0.34 10.9 0.0 1.6 1 0 0 1 1 1 0 GA-like domain FSH1 PF03959.13 KIY62108.1 - 9.5e-55 185.5 0.0 1.1e-54 185.3 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.20 KIY62108.1 - 0.026 14.1 0.0 11 5.6 0.0 2.7 2 1 1 3 3 3 0 alpha/beta hydrolase fold Tlr3_TMD PF17968.1 KIY62109.1 - 0.46 10.7 2.2 0.91 9.8 2.2 1.4 1 0 0 1 1 1 0 Toll-like receptor 3 trans-membrane domain PHO4 PF01384.20 KIY62110.1 - 6.5e-106 354.2 16.0 7.5e-106 354.0 16.0 1.0 1 0 0 1 1 1 1 Phosphate transporter family WH1 PF00568.23 KIY62111.1 - 1e-06 28.7 0.3 1.5e-06 28.1 0.3 1.2 1 0 0 1 1 1 1 WH1 domain DCP1 PF06058.13 KIY62111.1 - 0.013 15.4 0.2 0.041 13.8 0.2 1.8 1 1 0 1 1 1 0 Dcp1-like decapping family Pyr_redox_2 PF07992.14 KIY62112.1 - 6.8e-48 163.4 0.0 8e-48 163.2 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIY62112.1 - 5.8e-12 46.0 0.1 2.2e-09 37.8 0.1 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KIY62112.1 - 0.014 14.6 0.1 2.6 7.2 0.0 3.2 3 1 1 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase Pkinase PF00069.25 KIY62113.1 - 2.3e-63 214.1 0.0 7.7e-63 212.3 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY62113.1 - 5.1e-29 101.3 0.1 1.7e-20 73.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KIY62113.1 - 0.00044 19.7 0.1 0.016 14.6 0.0 2.5 3 0 0 3 3 3 1 Kinase-like Kdo PF06293.14 KIY62113.1 - 0.0054 16.1 0.1 0.019 14.3 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIY62113.1 - 0.0062 16.5 1.1 0.049 13.5 0.0 2.6 3 1 1 4 4 4 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KIY62113.1 - 0.012 14.6 0.0 0.021 13.8 0.0 1.5 1 1 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 KIY62113.1 - 0.056 13.0 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 RIO1 family Seadorna_VP7 PF07387.11 KIY62113.1 - 0.14 11.2 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Glyco_hydro_61 PF03443.14 KIY62115.1 - 4.6e-46 157.4 0.0 5.8e-46 157.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF3348 PF11828.8 KIY62117.1 - 0.083 12.5 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3348) GLTP PF08718.11 KIY62117.1 - 0.1 12.8 0.1 0.16 12.2 0.1 1.2 1 0 0 1 1 1 0 Glycolipid transfer protein (GLTP) Tektin PF03148.14 KIY62120.1 - 0.00052 18.9 3.5 0.00056 18.8 3.5 1.2 1 0 0 1 1 1 1 Tektin family bZIP_1 PF00170.21 KIY62120.1 - 0.0012 18.9 8.4 0.0031 17.6 8.4 1.8 1 0 0 1 1 1 1 bZIP transcription factor Zn_clus PF00172.18 KIY62120.1 - 0.0049 17.0 15.3 0.16 12.1 2.1 2.3 1 1 1 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain HAUS6_N PF14661.6 KIY62120.1 - 0.012 15.3 2.3 0.014 15.0 2.3 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus YabA PF06156.13 KIY62120.1 - 0.012 16.2 0.9 0.021 15.5 0.9 1.4 1 0 0 1 1 1 0 Initiation control protein YabA DUF1664 PF07889.12 KIY62120.1 - 0.047 13.7 1.1 0.066 13.3 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Rootletin PF15035.6 KIY62120.1 - 0.049 13.7 6.7 0.065 13.2 6.7 1.1 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Syntaxin PF00804.25 KIY62120.1 - 0.081 12.6 5.6 0.1 12.3 5.6 1.1 1 0 0 1 1 1 0 Syntaxin JIP_LZII PF16471.5 KIY62120.1 - 0.088 13.0 5.9 0.22 11.7 5.9 1.6 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II OmpH PF03938.14 KIY62120.1 - 0.12 12.7 3.1 0.17 12.3 3.1 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) TPR_MLP1_2 PF07926.12 KIY62120.1 - 0.17 12.0 6.8 0.1 12.7 4.1 1.5 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein bZIP_2 PF07716.15 KIY62120.1 - 0.19 11.8 10.1 0.24 11.5 7.0 2.4 1 1 1 2 2 2 0 Basic region leucine zipper DUF4140 PF13600.6 KIY62120.1 - 0.2 12.1 3.3 0.29 11.6 3.1 1.5 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) ZapB PF06005.12 KIY62120.1 - 0.22 12.0 8.1 0.25 11.8 5.5 1.9 1 1 1 2 2 2 0 Cell division protein ZapB GIT_CC PF16559.5 KIY62120.1 - 0.24 11.3 1.8 0.41 10.5 1.8 1.4 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor DivIC PF04977.15 KIY62120.1 - 0.25 11.1 4.5 0.59 9.9 4.5 1.7 1 0 0 1 1 1 0 Septum formation initiator DUF4407 PF14362.6 KIY62120.1 - 0.25 10.7 6.2 0.36 10.1 6.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Cep57_CLD_2 PF14197.6 KIY62120.1 - 0.39 10.8 8.0 3.5 7.8 7.8 2.5 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 Atg14 PF10186.9 KIY62120.1 - 0.6 9.1 8.8 0.86 8.6 8.8 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Med21 PF11221.8 KIY62120.1 - 0.64 10.3 4.1 0.67 10.2 3.5 1.3 1 1 0 1 1 1 0 Subunit 21 of Mediator complex DUF724 PF05266.14 KIY62120.1 - 0.69 9.7 6.4 0.83 9.5 6.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF724) FUSC PF04632.12 KIY62120.1 - 2.1 6.8 4.1 2.4 6.6 4.1 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family CENP-H PF05837.12 KIY62120.1 - 4.9 7.6 9.9 3.1 8.2 7.7 1.7 1 1 1 2 2 2 0 Centromere protein H (CENP-H) DNA_pol_phi PF04931.13 KIY62123.1 - 0.28 9.2 4.8 0.38 8.8 4.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi Na_trans_assoc PF06512.13 KIY62123.1 - 0.68 10.2 6.3 0.94 9.7 6.3 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated DUF2470 PF10615.9 KIY62123.1 - 5.1 7.8 7.7 2.4 8.9 1.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2470) Zn_clus PF00172.18 KIY62124.1 - 0.017 15.2 0.5 0.025 14.7 0.5 1.2 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_1 PF00561.20 KIY62125.1 - 6.2e-22 78.5 0.0 3.9e-19 69.3 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 KIY62125.1 - 5.4e-21 74.6 0.0 9.3e-21 73.9 0.0 1.3 1 0 0 1 1 1 1 TAP-like protein GMC_oxred_N PF00732.19 KIY62126.1 - 2.2e-73 247.2 0.0 2.7e-73 246.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIY62126.1 - 4.9e-37 127.6 0.1 8.6e-37 126.9 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KIY62126.1 - 1.4e-08 34.2 3.4 0.00038 19.6 0.9 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KIY62126.1 - 2.8e-07 30.4 0.1 0.00026 20.7 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KIY62126.1 - 2.1e-05 23.8 0.9 3.4e-05 23.1 0.9 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KIY62126.1 - 0.00014 22.0 0.3 0.00044 20.4 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KIY62126.1 - 0.00026 20.3 0.3 0.041 13.1 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KIY62126.1 - 0.001 18.4 0.1 0.0071 15.6 0.0 2.0 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 KIY62126.1 - 0.016 13.9 0.3 0.042 12.6 0.3 1.6 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 KIY62126.1 - 0.033 13.4 0.8 0.72 9.0 0.3 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KIY62126.1 - 0.04 13.3 4.0 2.9 7.1 1.2 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.22 KIY62126.1 - 0.12 11.5 2.1 0.92 8.5 0.6 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_3 PF01494.19 KIY62126.1 - 0.15 11.2 0.3 0.24 10.6 0.3 1.3 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.14 KIY62126.1 - 0.21 10.4 0.4 0.31 9.9 0.4 1.2 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_9 PF13454.6 KIY62126.1 - 4.7 7.2 5.8 1.2 9.1 0.2 2.6 3 0 0 3 3 2 0 FAD-NAD(P)-binding Zn_clus PF00172.18 KIY62127.1 - 3.3e-07 30.3 12.1 5.7e-07 29.6 12.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PTPlike_phytase PF14566.6 KIY62129.1 - 2.3e-135 446.9 0.0 2.2e-46 157.8 0.0 3.6 3 0 0 3 3 3 3 Inositol hexakisphosphate DSPc PF00782.20 KIY62129.1 - 2.4e-05 24.2 0.0 0.037 13.9 0.0 3.2 3 0 0 3 3 3 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KIY62129.1 - 0.00014 21.6 0.1 0.035 13.7 0.0 3.3 3 0 0 3 3 3 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KIY62129.1 - 0.0047 16.9 0.0 8.3 6.3 0.0 3.6 2 1 0 2 2 2 2 Tyrosine phosphatase family TFIIE-A_C PF11521.8 KIY62129.1 - 0.016 15.5 0.2 23 5.3 0.0 3.8 3 1 0 3 3 3 0 C-terminal general transcription factor TFIIE alpha PDDEXK_5 PF11645.8 KIY62131.1 - 0.12 12.3 0.1 0.21 11.6 0.1 1.3 1 0 0 1 1 1 0 PD-(D/E)XK endonuclease Acetyltransf_1 PF00583.25 KIY62132.1 - 1.4e-15 57.5 0.0 1.9e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KIY62132.1 - 3.7e-10 39.8 0.0 5.1e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KIY62132.1 - 5.9e-09 36.2 0.0 8.4e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIY62132.1 - 2.2e-08 34.0 0.0 3.3e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 KIY62132.1 - 1.7e-05 25.5 0.0 2.1e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KIY62132.1 - 3.3e-05 24.0 0.0 5e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KIY62132.1 - 5.5e-05 22.9 0.0 0.00016 21.4 0.0 1.6 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KIY62132.1 - 0.0043 17.2 0.0 0.0052 16.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KIY62132.1 - 0.095 12.8 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase HSF_DNA-bind PF00447.17 KIY62133.1 - 1.7e-29 102.3 2.8 1.7e-29 102.3 2.8 1.7 2 0 0 2 2 2 1 HSF-type DNA-binding Foie-gras_1 PF11817.8 KIY62133.1 - 0.048 13.3 0.5 0.064 12.8 0.5 1.1 1 0 0 1 1 1 0 Foie gras liver health family 1 STAT_alpha PF01017.20 KIY62133.1 - 0.12 12.2 2.0 0.2 11.5 2.0 1.3 1 0 0 1 1 1 0 STAT protein, all-alpha domain Oxysterol_BP PF01237.18 KIY62134.1 - 3.6e-57 193.9 0.3 2.1e-54 184.8 0.3 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein UPF0220 PF05255.11 KIY62135.1 - 3.8e-53 179.4 0.5 4.7e-53 179.1 0.5 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) HMG_box PF00505.19 KIY62138.1 - 3.7e-19 68.9 1.9 4.4e-19 68.7 1.9 1.1 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KIY62138.1 - 3.1e-11 43.7 2.5 3.1e-11 43.7 2.5 1.5 1 1 1 2 2 2 1 HMG-box domain CHDNT PF08073.12 KIY62138.1 - 0.0015 18.4 0.0 0.0023 17.9 0.0 1.2 1 0 0 1 1 1 1 CHDNT (NUC034) domain Mnd1 PF03962.15 KIY62139.1 - 6.3e-25 87.2 0.1 1.1e-24 86.4 0.1 1.5 1 0 0 1 1 1 1 Mnd1 HTH domain LZ3wCH PF18517.1 KIY62139.1 - 8e-06 25.9 0.4 8e-06 25.9 0.4 2.0 3 0 0 3 3 3 1 Leucine zipper with capping helix domain Fe-S_assembly PF04384.13 KIY62139.1 - 0.14 12.8 0.9 25 5.6 0.1 3.1 2 1 1 3 3 3 0 Iron-sulphur cluster assembly DUF1216 PF06746.11 KIY62139.1 - 0.49 10.4 5.0 1.1 9.3 4.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1216) Oxidored_q6 PF01058.22 KIY62140.1 - 4.7e-22 78.2 0.1 7.1e-22 77.6 0.1 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit ArfGap PF01412.18 KIY62141.1 - 1.8e-42 144.1 0.4 2.6e-42 143.6 0.4 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Pkinase PF00069.25 KIY62142.1 - 9.3e-51 172.7 0.0 1.2e-37 129.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIY62142.1 - 6.1e-21 74.9 0.0 1.2e-20 73.9 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY62142.1 - 0.00027 20.3 0.0 0.00039 19.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KIY62142.1 - 0.00034 20.6 0.1 0.00058 19.9 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KIY62142.1 - 0.0042 16.1 0.1 0.0077 15.2 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KIY62142.1 - 0.027 13.3 0.0 0.04 12.7 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 KIY62142.1 - 0.042 13.2 0.1 0.064 12.6 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_transpo PF04515.12 KIY62144.1 - 8.2e-78 261.9 17.0 8.2e-78 261.9 17.0 2.3 2 1 0 2 2 2 1 Plasma-membrane choline transporter Solute_trans_a PF03619.16 KIY62145.1 - 1.1e-82 277.6 16.5 1.3e-82 277.3 16.5 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Glycos_transf_4 PF00953.21 KIY62145.1 - 0.82 9.6 6.8 0.13 12.2 1.2 2.3 2 1 0 2 2 2 0 Glycosyl transferase family 4 PHD_3 PF13922.6 KIY62146.1 - 0.1 13.0 0.4 0.28 11.6 0.4 1.7 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx S4 PF01479.25 KIY62147.1 - 2.1e-11 43.3 1.4 2.1e-11 43.3 1.4 2.8 3 0 0 3 3 3 1 S4 domain Ribosomal_S4 PF00163.19 KIY62147.1 - 1.6e-06 29.0 0.1 2.6e-06 28.2 0.1 1.6 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Ribosomal_L21e PF01157.18 KIY62148.1 - 1.4e-44 150.0 4.0 2.4e-44 149.3 4.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L21e Surface_Ag_2 PF01617.17 KIY62148.1 - 0.02 14.3 0.1 0.022 14.2 0.1 1.2 1 0 0 1 1 1 0 Surface antigen ubiquitin PF00240.23 KIY62149.1 - 2.6e-25 88.0 0.3 2.8e-25 87.8 0.3 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KIY62149.1 - 4.8e-13 48.7 0.6 5.3e-13 48.6 0.6 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 KIY62149.1 - 4.3e-05 23.4 0.0 5.1e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_2 PF14560.6 KIY62149.1 - 0.00034 21.0 0.0 0.00046 20.6 0.0 1.3 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_5 PF18037.1 KIY62149.1 - 0.059 13.7 0.1 0.07 13.5 0.1 1.2 1 0 0 1 1 1 0 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 KIY62149.1 - 0.069 13.3 0.1 0.18 11.9 0.1 1.7 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like S4 PF01479.25 KIY62150.1 - 8.5e-12 44.6 0.0 3.2e-11 42.8 0.0 2.0 2 0 0 2 2 2 1 S4 domain S4_2 PF13275.6 KIY62150.1 - 0.14 12.0 0.0 0.64 9.9 0.0 2.1 2 0 0 2 2 2 0 S4 domain DUF966 PF06136.13 KIY62150.1 - 0.15 11.7 4.9 0.11 12.2 3.5 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF966) AA_permease_2 PF13520.6 KIY62151.1 - 4.7e-65 220.1 53.4 5.9e-65 219.8 53.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KIY62151.1 - 9e-12 44.3 46.7 1.3e-11 43.8 46.7 1.1 1 0 0 1 1 1 1 Amino acid permease PAP2 PF01569.21 KIY62152.1 - 3.2e-17 62.6 4.9 3.2e-17 62.6 4.9 1.9 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 KIY62152.1 - 0.0015 18.2 3.7 0.0015 18.2 3.7 1.9 2 0 0 2 2 2 1 PAP2 superfamily Cnn_1N PF07989.11 KIY62153.1 - 6e-24 84.0 4.5 6e-24 84.0 4.5 12.5 8 4 4 12 12 12 2 Centrosomin N-terminal motif 1 Spc7 PF08317.11 KIY62153.1 - 1.9e-06 27.0 145.6 0.011 14.6 18.7 8.1 2 2 8 10 10 10 10 Spc7 kinetochore protein HIP1_clath_bdg PF16515.5 KIY62153.1 - 0.0042 17.7 6.7 0.0042 17.7 6.7 12.4 3 3 10 13 13 13 2 Clathrin-binding domain of Huntingtin-interacting protein 1 ZapB PF06005.12 KIY62153.1 - 0.0045 17.4 3.6 0.0045 17.4 3.6 14.3 5 4 7 12 12 12 3 Cell division protein ZapB DUF948 PF06103.11 KIY62153.1 - 0.066 13.5 0.4 0.066 13.5 0.4 9.2 5 3 5 10 10 10 0 Bacterial protein of unknown function (DUF948) AAA_13 PF13166.6 KIY62153.1 - 0.66 8.5 101.8 0.097 11.3 22.6 5.2 2 1 3 5 5 5 0 AAA domain DUF1664 PF07889.12 KIY62153.1 - 2.1 8.4 76.9 0.32 11.0 7.9 10.4 2 2 8 12 12 12 0 Protein of unknown function (DUF1664) 4HBT PF03061.22 KIY62154.1 - 5.4e-06 26.7 0.0 0.19 12.1 0.0 2.6 2 0 0 2 2 2 2 Thioesterase superfamily zf-MYND PF01753.18 KIY62156.1 - 1.5e-09 37.8 11.0 4e-09 36.4 11.0 1.8 1 0 0 1 1 1 1 MYND finger ubiquitin PF00240.23 KIY62157.1 - 1.8e-09 37.2 0.0 3.2e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KIY62157.1 - 8.7e-06 25.5 0.0 1.4e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like PQ-loop PF04193.14 KIY62158.1 - 6.1e-27 93.2 4.2 4.6e-13 48.7 0.2 2.7 2 0 0 2 2 2 2 PQ loop repeat Lipase_3 PF01764.25 KIY62159.1 - 5.6e-28 97.6 0.0 8.1e-28 97.1 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KIY62159.1 - 0.011 16.4 2.6 0.016 15.8 2.3 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.13 KIY62159.1 - 0.058 13.1 0.0 0.094 12.4 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_5 PF12695.7 KIY62159.1 - 0.071 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIY62159.1 - 0.092 12.0 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF2974 PF11187.8 KIY62159.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Lipase_3 PF01764.25 KIY62160.1 - 7.2e-24 84.3 0.0 1e-23 83.8 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KIY62160.1 - 0.0028 18.3 0.5 0.0058 17.3 0.3 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.13 KIY62160.1 - 0.049 13.3 0.0 0.075 12.7 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein UPF0227 PF05728.12 KIY62160.1 - 0.16 11.9 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Tetraspanin PF00335.20 KIY62161.1 - 6.3e-09 35.9 6.3 1e-08 35.2 6.3 1.3 1 0 0 1 1 1 1 Tetraspanin family FTR1 PF03239.14 KIY62161.1 - 0.0026 17.0 0.8 0.0048 16.1 0.8 1.4 1 0 0 1 1 1 1 Iron permease FTR1 family FA_desaturase PF00487.24 KIY62161.1 - 0.19 11.6 6.8 0.38 10.6 5.3 1.9 2 0 0 2 2 2 0 Fatty acid desaturase PTPA PF03095.15 KIY62162.1 - 4.4e-103 344.9 0.0 5.1e-103 344.7 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein DUF1180 PF06679.12 KIY62166.1 - 0.02 15.3 0.0 0.02 15.3 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1180) DUF2909 PF11137.8 KIY62166.1 - 0.067 13.1 0.1 0.11 12.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2909) adh_short PF00106.25 KIY62167.1 - 6.9e-18 64.8 0.0 2.2e-17 63.2 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIY62167.1 - 4.5e-07 29.7 0.0 9e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIY62167.1 - 0.0026 17.7 0.0 0.0053 16.7 0.0 1.5 1 0 0 1 1 1 1 KR domain RCR PF12273.8 KIY62168.1 - 7.4e-06 26.6 8.0 1.3e-05 25.8 8.0 1.4 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red CYYR1 PF10873.8 KIY62168.1 - 0.0002 21.8 6.7 0.0002 21.8 6.7 1.8 1 1 1 2 2 2 1 Cysteine and tyrosine-rich protein 1 Shisa PF13908.6 KIY62168.1 - 0.017 15.3 0.4 0.03 14.6 0.1 1.5 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator EphA2_TM PF14575.6 KIY62168.1 - 0.058 14.3 0.0 0.098 13.5 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Amnionless PF14828.6 KIY62168.1 - 0.088 11.6 0.0 0.096 11.5 0.0 1.0 1 0 0 1 1 1 0 Amnionless PDGLE PF13190.6 KIY62168.1 - 0.32 10.9 0.9 0.58 10.1 0.9 1.5 1 1 0 1 1 1 0 PDGLE domain SARAF PF06682.12 KIY62168.1 - 0.99 9.0 5.3 4.5 6.8 5.3 1.9 1 1 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Mito_carr PF00153.27 KIY62169.1 - 3.3e-74 244.9 0.6 2.6e-26 91.4 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Glyco_hydro_7 PF00840.20 KIY62172.1 - 3.4e-207 688.4 13.2 3.8e-207 688.2 13.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Palm_thioest PF02089.15 KIY62174.1 - 0.00068 19.5 0.0 0.00099 19.0 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF676 PF05057.14 KIY62174.1 - 0.0061 16.1 0.0 0.011 15.2 0.0 1.5 1 1 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 KIY62174.1 - 0.011 15.5 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein ATG16 PF08614.11 KIY62175.1 - 0.0035 17.6 28.4 0.0035 17.6 28.4 8.3 2 1 4 7 7 7 2 Autophagy protein 16 (ATG16) DSPc PF00782.20 KIY62175.1 - 0.16 11.8 2.1 0.34 10.7 0.2 2.5 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain Fez1 PF06818.15 KIY62175.1 - 3.6 8.0 120.9 0.018 15.5 19.6 6.7 1 1 4 6 6 6 0 Fez1 ATP-synt_C PF00137.21 KIY62180.1 - 1.7e-34 118.0 34.0 6.5e-22 77.6 15.4 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Pkinase PF00069.25 KIY62181.1 - 5.3e-44 150.5 0.0 5.3e-31 108.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIY62181.1 - 7e-31 107.4 0.0 8e-25 87.6 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIY62181.1 - 1e-06 27.8 0.0 1.9e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase FXR_C1 PF16096.5 KIY62181.1 - 0.001 19.2 0.7 0.0039 17.4 0.7 2.0 1 0 0 1 1 1 1 Fragile X-related 1 protein C-terminal region 2 APH PF01636.23 KIY62181.1 - 0.0015 18.5 0.0 0.0024 17.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KIY62181.1 - 0.013 14.5 0.0 0.019 13.9 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 KIY62181.1 - 0.15 11.3 0.0 3.6 6.8 0.0 2.3 2 0 0 2 2 2 0 Kinase-like RIO1 PF01163.22 KIY62181.1 - 0.16 11.6 0.0 0.47 10.0 0.0 1.7 2 0 0 2 2 2 0 RIO1 family DIOX_N PF14226.6 KIY62182.1 - 4.3e-33 114.6 0.0 6.4e-33 114.0 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KIY62182.1 - 2.7e-21 75.9 0.0 5.4e-21 75.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily BCS1_N PF08740.11 KIY62183.1 - 1.2e-44 152.5 2.2 1.2e-44 152.5 2.2 2.7 2 1 0 2 2 2 1 BCS1 N terminal AAA PF00004.29 KIY62183.1 - 8.3e-15 55.4 0.0 4.4e-13 49.8 0.0 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KIY62183.1 - 0.00014 22.3 1.8 0.00029 21.3 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 KIY62183.1 - 0.0017 18.5 0.0 0.0071 16.5 0.0 2.2 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KIY62183.1 - 0.014 15.2 0.0 0.014 15.2 0.0 2.0 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase NACHT PF05729.12 KIY62183.1 - 0.1 12.5 0.1 0.3 11.0 0.1 1.8 1 0 0 1 1 1 0 NACHT domain RuvB_N PF05496.12 KIY62183.1 - 0.11 12.3 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain XRN_M PF17846.1 KIY62183.1 - 1.8 7.4 14.2 3.5 6.5 14.2 1.4 1 0 0 1 1 1 0 Xrn1 helical domain AAA_23 PF13476.6 KIY62183.1 - 4.8 7.6 23.2 1.8 9.0 14.0 3.1 3 0 0 3 3 3 0 AAA domain zf-H2C2_2 PF13465.6 KIY62184.1 - 5.4e-05 23.4 0.7 0.0016 18.8 0.0 3.2 3 0 0 3 3 3 1 Zinc-finger double domain HCV_capsid PF01543.17 KIY62184.1 - 0.0078 16.4 0.4 0.028 14.6 0.4 1.9 1 0 0 1 1 1 1 Hepatitis C virus capsid protein zf-C2H2_4 PF13894.6 KIY62184.1 - 0.014 16.2 3.3 0.075 13.9 0.0 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KIY62184.1 - 0.038 14.4 0.0 0.038 14.4 0.0 3.9 4 2 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KIY62184.1 - 2.3 8.3 0.0 2.3 8.3 0.0 2.7 3 0 0 3 3 3 0 C2H2-type zinc finger DUF4581 PF15167.6 KIY62185.1 - 0.036 14.2 0.1 0.05 13.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4581) FliT PF05400.13 KIY62185.1 - 0.54 11.1 7.7 8 7.4 7.7 2.4 1 1 0 1 1 1 0 Flagellar protein FliT Cauli_VI PF01693.16 KIY62186.1 - 5e-05 23.5 2.6 0.003 17.8 1.5 2.7 2 0 0 2 2 2 2 Caulimovirus viroplasmin PriCT_2 PF08707.11 KIY62186.1 - 0.055 13.8 0.1 0.15 12.5 0.1 1.7 1 0 0 1 1 1 0 Primase C terminal 2 (PriCT-2) HEAT PF02985.22 KIY62189.1 - 1.2e-13 50.1 13.9 0.15 12.4 0.0 10.4 11 0 0 11 11 10 4 HEAT repeat HEAT_EZ PF13513.6 KIY62189.1 - 7.2e-13 48.7 17.6 0.00071 20.0 0.0 9.9 13 1 1 14 14 12 4 HEAT-like repeat HEAT_2 PF13646.6 KIY62189.1 - 6.9e-10 39.2 4.6 1.9 9.0 0.0 9.1 7 3 4 11 11 11 2 HEAT repeats Arm PF00514.23 KIY62189.1 - 1.2e-05 25.2 8.0 4.2 7.6 0.0 7.1 8 0 0 8 8 8 3 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 KIY62189.1 - 4e-05 23.7 0.2 0.032 14.3 0.0 3.9 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 IBN_N PF03810.19 KIY62189.1 - 0.00041 20.2 0.1 0.005 16.7 0.0 2.7 2 0 0 2 2 2 1 Importin-beta N-terminal domain DUF3385 PF11865.8 KIY62189.1 - 0.0023 17.8 0.6 61 3.5 0.0 5.7 5 1 0 6 6 6 0 Domain of unknown function (DUF3385) Xpo1 PF08389.12 KIY62189.1 - 0.0043 17.1 0.0 0.7 10.0 0.0 4.0 3 0 0 3 3 3 1 Exportin 1-like protein BP28CT PF08146.12 KIY62189.1 - 0.019 14.8 0.1 0.97 9.3 0.0 3.8 4 1 1 5 5 5 0 BP28CT (NUC211) domain Vac14_Fab1_bd PF12755.7 KIY62189.1 - 0.042 14.4 0.1 1.6 9.4 0.0 3.8 4 1 1 5 5 5 0 Vacuolar 14 Fab1-binding region RIX1 PF08167.12 KIY62189.1 - 0.082 12.6 0.0 3.3 7.4 0.0 3.7 3 1 0 3 3 3 0 rRNA processing/ribosome biogenesis Tti2 PF10521.9 KIY62189.1 - 0.12 11.9 0.2 0.86 9.1 0.0 2.5 3 0 0 3 3 3 0 Tti2 family HMG_box PF00505.19 KIY62190.1 - 1.1e-16 61.0 0.2 2.3e-16 60.0 0.2 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KIY62190.1 - 3.7e-14 53.1 0.8 1.6e-13 51.0 0.1 2.1 2 0 0 2 2 2 1 HMG-box domain RFX_DNA_binding PF02257.15 KIY62192.1 - 0.089 13.4 0.0 0.34 11.6 0.0 1.9 2 0 0 2 2 2 0 RFX DNA-binding domain Trypsin_2 PF13365.6 KIY62193.1 - 8e-05 23.6 0.1 0.0023 18.8 0.0 2.3 2 0 0 2 2 2 1 Trypsin-like peptidase domain Peptidase_S32 PF05579.13 KIY62193.1 - 0.00018 20.8 0.1 0.00034 19.9 0.1 1.3 1 0 0 1 1 1 1 Equine arteritis virus serine endopeptidase S32 Spc7 PF08317.11 KIY62193.1 - 0.0016 17.4 0.1 0.0021 17.0 0.1 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF211 PF02680.14 KIY62193.1 - 0.0021 18.2 0.0 0.0041 17.2 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized ArCR, COG1888 Peptidase_S3 PF00944.19 KIY62193.1 - 0.06 13.1 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 Alphavirus core protein DUF4298 PF14131.6 KIY62193.1 - 0.072 13.1 0.1 0.13 12.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4298) ATP-synt_DE PF00401.20 KIY62193.1 - 0.11 12.8 3.7 0.28 11.5 3.7 1.6 1 0 0 1 1 1 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain CDH-cyt PF16010.5 KIY62194.1 - 9.9e-50 168.7 4.2 1.3e-49 168.3 3.3 1.7 2 0 0 2 2 2 1 Cytochrome domain of cellobiose dehydrogenase GMC_oxred_N PF00732.19 KIY62194.1 - 5.4e-20 72.0 0.0 1.2e-19 70.8 0.0 1.7 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIY62194.1 - 6.8e-18 65.6 0.0 1.8e-17 64.2 0.0 1.8 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KIY62194.1 - 2.1e-06 27.1 0.0 2.5e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KIY62194.1 - 7.5e-06 26.1 0.0 3.4e-05 24.0 0.0 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KIY62194.1 - 7.1e-05 22.2 0.1 0.00012 21.5 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KIY62194.1 - 9.8e-05 22.1 0.5 0.00048 19.8 0.5 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KIY62194.1 - 0.00012 21.4 0.0 0.0017 17.6 0.2 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KIY62194.1 - 0.00023 20.5 0.1 0.00041 19.7 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KIY62194.1 - 0.00096 18.0 0.1 0.0018 17.1 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 KIY62194.1 - 0.0059 15.9 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Amino_oxidase PF01593.24 KIY62194.1 - 0.064 12.5 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 KIY62194.1 - 0.074 12.1 0.1 0.12 11.4 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Cation_efflux PF01545.21 KIY62195.1 - 6e-09 35.9 8.6 1.8e-08 34.4 8.6 1.7 1 1 0 1 1 1 1 Cation efflux family Na_Ca_ex PF01699.24 KIY62198.1 - 1.3e-13 51.2 29.5 8.7e-09 35.5 11.2 2.7 3 0 0 3 3 3 2 Sodium/calcium exchanger protein COesterase PF00135.28 KIY62199.1 - 1.4e-83 281.5 0.0 1.6e-83 281.3 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KIY62199.1 - 2.1e-08 34.3 1.3 2.2e-07 30.9 1.3 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIY62199.1 - 0.00094 19.8 2.1 0.00095 19.8 0.1 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KIY62199.1 - 0.0015 18.1 0.3 0.0027 17.2 0.0 1.5 2 0 0 2 2 2 1 Prolyl oligopeptidase family AAA PF00004.29 KIY62200.1 - 2.1e-42 144.7 0.0 3.9e-42 143.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 KIY62200.1 - 5.8e-29 99.9 0.3 1.5e-28 98.6 0.3 1.8 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 KIY62200.1 - 9e-23 80.1 7.2 1.6e-22 79.3 7.2 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 KIY62200.1 - 1.2e-07 31.4 0.0 4.1e-07 29.7 0.0 1.9 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 KIY62200.1 - 7.1e-06 25.9 0.0 1.5e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KIY62200.1 - 7.9e-06 26.3 0.1 4.5e-05 23.9 0.1 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KIY62200.1 - 1.1e-05 25.8 0.8 0.0099 16.2 0.1 2.7 2 1 1 3 3 3 2 AAA domain AAA_14 PF13173.6 KIY62200.1 - 2.9e-05 24.1 0.1 9.7e-05 22.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KIY62200.1 - 3.3e-05 23.9 0.0 0.0001 22.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 KIY62200.1 - 3.8e-05 23.5 0.0 7.4e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein DUF815 PF05673.13 KIY62200.1 - 0.0008 18.6 0.0 0.0029 16.8 0.0 1.9 2 1 1 3 3 3 1 Protein of unknown function (DUF815) AAA_2 PF07724.14 KIY62200.1 - 0.00095 19.3 0.0 0.0049 17.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_24 PF13479.6 KIY62200.1 - 0.0012 18.7 0.0 0.0028 17.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 KIY62200.1 - 0.0012 18.1 0.1 0.003 16.8 0.0 1.7 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_18 PF13238.6 KIY62200.1 - 0.0017 18.9 0.0 0.0038 17.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KIY62200.1 - 0.002 18.3 0.0 0.0047 17.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KIY62200.1 - 0.0044 17.4 0.0 0.012 16.0 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_25 PF13481.6 KIY62200.1 - 0.0064 16.1 0.1 0.75 9.3 0.1 2.5 1 1 1 2 2 2 1 AAA domain ATPase PF06745.13 KIY62200.1 - 0.015 14.7 0.0 3.3 7.0 0.0 2.3 1 1 1 2 2 2 0 KaiC AAA_17 PF13207.6 KIY62200.1 - 0.018 15.5 0.1 0.064 13.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KIY62200.1 - 0.018 14.3 0.1 2.3 7.5 0.1 2.4 1 1 1 2 2 2 0 Zeta toxin Mg_chelatase PF01078.21 KIY62200.1 - 0.041 13.3 0.0 0.081 12.3 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 KIY62200.1 - 0.043 13.7 0.0 0.34 10.8 0.0 2.1 1 1 1 2 2 2 0 NACHT domain TniB PF05621.11 KIY62200.1 - 0.053 12.9 0.0 9 5.7 0.0 2.4 1 1 0 2 2 2 0 Bacterial TniB protein AAA_7 PF12775.7 KIY62200.1 - 0.055 13.0 0.0 0.21 11.1 0.0 2.0 2 1 0 2 2 1 0 P-loop containing dynein motor region Parvo_NS1 PF01057.17 KIY62200.1 - 0.064 12.3 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ATPase_2 PF01637.18 KIY62200.1 - 0.079 12.9 0.0 1.3 8.9 0.0 2.4 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea Viral_helicase1 PF01443.18 KIY62200.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Sigma54_activat PF00158.26 KIY62200.1 - 0.13 12.0 0.0 0.69 9.6 0.0 2.0 1 1 0 2 2 2 0 Sigma-54 interaction domain Tma16 PF11176.8 KIY62200.1 - 0.14 12.0 0.6 0.29 11.0 0.6 1.5 1 0 0 1 1 1 0 Translation machinery-associated protein 16 AFG1_ATPase PF03969.16 KIY62200.1 - 0.15 10.9 0.4 0.97 8.3 0.0 2.2 2 0 0 2 2 2 0 AFG1-like ATPase PhoH PF02562.16 KIY62200.1 - 0.15 11.5 1.4 0.18 11.2 0.1 1.7 2 0 0 2 2 1 0 PhoH-like protein Torsin PF06309.11 KIY62200.1 - 0.18 11.9 0.0 0.41 10.8 0.0 1.6 1 0 0 1 1 1 0 Torsin SHS2_Rpb7-N PF03876.17 KIY62201.1 - 2e-15 56.9 0.0 2.9e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 KIY62201.1 - 8.7e-09 35.6 0.0 2e-08 34.4 0.0 1.6 1 1 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.12 KIY62201.1 - 0.058 13.6 0.0 0.094 13.0 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 Glyco_hydro_61 PF03443.14 KIY62202.1 - 2.3e-55 187.7 0.1 2.6e-55 187.6 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Glyco_hydro_61 PF03443.14 KIY62203.1 - 1.1e-56 192.0 0.7 1.3e-56 191.8 0.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 PsbK PF02533.15 KIY62203.1 - 0.017 15.3 0.1 0.11 12.7 0.0 2.2 2 0 0 2 2 2 0 Photosystem II 4 kDa reaction centre component Caleosin PF05042.13 KIY62204.1 - 1.7e-53 181.0 0.1 2e-53 180.8 0.1 1.1 1 0 0 1 1 1 1 Caleosin related protein Acetyltransf_1 PF00583.25 KIY62205.1 - 7.9e-10 39.0 0.0 1.8e-09 37.8 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KIY62205.1 - 3.8e-09 36.9 0.0 2.9e-08 34.0 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KIY62205.1 - 1.4e-08 34.7 0.0 1.1e-07 31.8 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KIY62205.1 - 1.1e-07 31.9 0.2 0.0035 17.4 0.0 3.0 2 1 1 3 3 3 2 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIY62205.1 - 0.0011 18.9 0.0 0.0021 18.0 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 KIY62205.1 - 0.0059 16.7 0.0 0.013 15.6 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase TIP120 PF08623.10 KIY62208.1 - 7.4e-57 191.8 3.3 2e-55 187.1 0.2 3.9 4 0 0 4 4 4 1 TATA-binding protein interacting (TIP20) HEAT PF02985.22 KIY62208.1 - 8.8e-13 47.3 24.3 0.065 13.5 0.0 13.3 15 0 0 15 15 13 1 HEAT repeat HEAT_2 PF13646.6 KIY62208.1 - 1.2e-12 48.0 19.5 0.0014 19.0 1.3 8.4 6 2 5 11 11 10 5 HEAT repeats HEAT_EZ PF13513.6 KIY62208.1 - 3.1e-08 34.0 24.9 4.9 7.8 0.3 12.2 12 1 2 14 14 14 1 HEAT-like repeat Cnd1 PF12717.7 KIY62208.1 - 2e-07 31.2 5.1 0.091 12.8 0.1 5.5 4 2 2 6 6 6 3 non-SMC mitotic condensation complex subunit 1 Tti2 PF10521.9 KIY62208.1 - 3.1e-07 30.2 2.3 4.1 6.8 0.0 5.6 5 0 0 5 5 5 2 Tti2 family Adaptin_N PF01602.20 KIY62208.1 - 1.6e-05 23.7 9.9 0.44 9.0 0.2 5.8 4 2 2 6 6 6 4 Adaptin N terminal region RTP1_C1 PF10363.9 KIY62208.1 - 4.2e-05 23.7 3.0 0.2 11.9 0.1 4.9 4 2 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 KIY62208.1 - 7.1e-05 22.5 5.0 0.33 10.5 0.1 5.5 6 0 0 6 6 6 2 CLASP N terminal Vac14_Fab1_bd PF12755.7 KIY62208.1 - 0.00098 19.7 1.9 17 6.1 0.1 6.6 6 2 2 8 8 8 0 Vacuolar 14 Fab1-binding region ParcG PF10274.9 KIY62208.1 - 0.0055 16.8 0.8 0.27 11.4 0.0 3.6 5 0 0 5 5 4 1 Parkin co-regulated protein Telomere_reg-2 PF10193.9 KIY62208.1 - 0.012 16.0 5.8 0.24 11.9 0.0 4.9 5 0 0 5 5 5 0 Telomere length regulation protein API5 PF05918.11 KIY62208.1 - 0.12 11.2 1.2 2 7.2 0.3 3.1 4 0 0 4 4 4 0 Apoptosis inhibitory protein 5 (API5) V-ATPase_H_C PF11698.8 KIY62208.1 - 0.12 12.5 4.7 0.98 9.5 0.4 4.2 5 0 0 5 5 4 0 V-ATPase subunit H MMS19_C PF12460.8 KIY62208.1 - 0.13 11.4 0.1 0.13 11.4 0.1 4.8 5 1 0 5 5 5 0 RNAPII transcription regulator C-terminal DUF4611 PF15387.6 KIY62208.1 - 0.19 12.0 2.0 0.93 9.7 2.0 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) WAPL PF07814.13 KIY62208.1 - 0.55 9.0 3.6 0.98 8.1 0.2 2.9 3 1 1 4 4 4 0 Wings apart-like protein regulation of heterochromatin SNF2_N PF00176.23 KIY62210.1 - 1.5e-16 60.1 0.0 3.6e-16 58.8 0.0 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KIY62210.1 - 6.2e-11 42.6 0.0 1.3e-10 41.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 KIY62210.1 - 0.0014 17.9 0.0 0.0024 17.1 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 KIY62210.1 - 0.0091 16.0 0.0 0.025 14.6 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SDA1 PF05285.12 KIY62210.1 - 0.012 15.1 1.8 0.018 14.5 1.8 1.2 1 0 0 1 1 1 0 SDA1 YL1 PF05764.13 KIY62210.1 - 0.53 10.4 7.2 0.97 9.5 7.2 1.3 1 0 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.14 KIY62210.1 - 0.6 8.3 2.8 1.1 7.5 2.8 1.3 1 0 0 1 1 1 0 CDC45-like protein Zn_clus PF00172.18 KIY62211.1 - 2.5 8.3 13.2 4.9 7.4 8.3 2.2 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 KIY62212.1 - 0.012 15.7 10.6 0.083 13.0 10.6 2.1 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 KIY62214.1 - 0.043 13.9 3.0 0.077 13.1 3.0 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 KIY62215.1 - 3 8.0 10.8 5.3 7.2 3.5 2.2 1 1 1 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Plavaka PF18759.1 KIY62218.1 - 1.5e-113 379.3 0.0 2.3e-113 378.7 0.0 1.3 1 0 0 1 1 1 1 Plavaka transposase NPP1 PF05630.11 KIY62218.1 - 0.013 15.6 0.6 0.03 14.4 0.6 1.6 1 0 0 1 1 1 0 Necrosis inducing protein (NPP1) zf-C2H2 PF00096.26 KIY62219.1 - 0.022 15.2 1.0 0.073 13.6 1.0 2.0 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIY62219.1 - 0.22 12.4 1.0 0.74 10.8 0.6 2.2 1 1 0 1 1 1 0 C2H2-type zinc finger TIMELESS PF04821.14 KIY62221.1 - 0.23 10.7 0.9 0.38 10.0 0.9 1.2 1 0 0 1 1 1 0 Timeless protein Ribosomal_S2 PF00318.20 KIY62223.1 - 1.4e-28 99.6 0.3 1e-14 54.3 0.2 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 KIY62223.1 - 4.9e-09 37.4 10.4 8.6e-09 36.6 10.4 1.5 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus MFS_1 PF07690.16 KIY62224.1 - 1.5e-28 99.7 27.3 1.5e-28 99.7 27.3 1.5 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 KIY62224.1 - 9.4e-08 31.7 4.5 9.4e-08 31.7 4.5 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB F-box-like PF12937.7 KIY62226.1 - 0.049 13.5 0.5 0.11 12.5 0.5 1.5 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 KIY62227.1 - 0.047 13.6 0.1 0.13 12.2 0.1 1.7 1 0 0 1 1 1 0 F-box domain vATP-synt_E PF01991.18 KIY62228.1 - 4e-55 186.3 13.1 4.8e-55 186.1 13.1 1.1 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit RapH_N PF18801.1 KIY62228.1 - 0.042 13.9 1.0 0.042 13.9 1.0 2.6 2 1 0 2 2 2 0 response regulator aspartate phosphatase H, N terminal BNR_2 PF13088.6 KIY62228.1 - 0.043 13.1 0.1 0.068 12.5 0.1 1.4 1 1 0 1 1 1 0 BNR repeat-like domain F-box_4 PF15966.5 KIY62229.1 - 0.0018 18.1 0.0 0.014 15.2 0.0 2.3 2 0 0 2 2 2 1 F-box F-box-like PF12937.7 KIY62229.1 - 0.031 14.2 0.1 0.092 12.7 0.1 1.8 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 KIY62229.1 - 0.051 13.5 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 F-box domain Elf1 PF05129.13 KIY62229.1 - 0.17 11.9 2.3 0.47 10.5 2.3 1.8 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like G-alpha PF00503.20 KIY62230.1 - 5.7e-107 357.9 0.0 7.2e-107 357.6 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KIY62230.1 - 1.4e-11 44.2 0.0 9.4e-08 31.7 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 KIY62230.1 - 0.012 15.8 0.0 0.41 10.9 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 KIY62230.1 - 0.042 13.2 0.1 2.3 7.5 0.0 2.3 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region F-box-like PF12937.7 KIY62231.1 - 0.00031 20.6 1.8 0.00098 19.0 0.0 2.8 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 KIY62231.1 - 0.0009 19.1 0.0 0.0025 17.7 0.0 1.7 1 0 0 1 1 1 1 F-box domain Trypan_PARP PF05887.11 KIY62234.1 - 7.2e-05 22.8 17.8 0.00017 21.6 17.8 1.7 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) NICE-1 PF15845.5 KIY62234.1 - 0.078 13.8 0.5 0.16 12.7 0.5 1.5 1 0 0 1 1 1 0 Cysteine-rich C-terminal 1 family TFIIA PF03153.13 KIY62234.1 - 0.12 12.4 8.9 0.15 12.1 8.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NOA36 PF06524.12 KIY62234.1 - 4.2 6.6 11.4 5.7 6.2 11.4 1.2 1 0 0 1 1 1 0 NOA36 protein Herpes_DNAp_acc PF04929.12 KIY62236.1 - 6.1 5.7 9.0 8.5 5.2 9.0 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Herpes_LMP1 PF05297.11 KIY62238.1 - 4 6.5 5.1 6 5.9 5.1 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) WD40 PF00400.32 KIY62240.1 - 1.1e-05 26.1 0.3 3.1e-05 24.7 0.2 1.8 2 0 0 2 2 2 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY62240.1 - 0.00011 22.4 0.0 0.0005 20.3 0.0 1.8 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain KTSC PF13619.6 KIY62240.1 - 0.0019 18.0 0.0 0.026 14.3 0.0 2.1 2 0 0 2 2 2 1 KTSC domain SepQ PF06622.11 KIY62240.1 - 0.028 13.5 0.0 0.028 13.5 0.0 1.1 1 0 0 1 1 1 0 SepQ protein PD40 PF07676.12 KIY62240.1 - 0.046 13.7 0.0 0.091 12.7 0.0 1.4 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat Nbas_N PF15492.6 KIY62240.1 - 0.068 12.5 0.0 0.097 12.0 0.0 1.2 1 0 0 1 1 1 0 Neuroblastoma-amplified sequence, N terminal Exo_endo_phos PF03372.23 KIY62241.1 - 0.00035 20.2 0.0 0.00057 19.5 0.0 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Peptidase_M35 PF02102.15 KIY62242.1 - 7.7e-15 54.6 6.0 1e-14 54.2 6.0 1.1 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 KIY62242.1 - 2.1e-13 51.1 0.2 3.8e-13 50.2 0.2 1.4 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase Reprolysin_4 PF13583.6 KIY62242.1 - 0.05 13.2 2.3 0.19 11.3 0.0 2.6 3 0 0 3 3 3 0 Metallo-peptidase family M12B Reprolysin-like Ribosomal_L38e PF01781.18 KIY62242.1 - 0.063 13.4 0.4 1.8 8.7 0.0 2.3 1 1 1 2 2 2 0 Ribosomal L38e protein family Aspzincin_M35 PF14521.6 KIY62243.1 - 3.3e-15 56.9 2.4 5.8e-15 56.1 2.4 1.3 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase Peptidase_M35 PF02102.15 KIY62243.1 - 1.1e-09 37.7 8.9 1.4e-09 37.4 8.9 1.1 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 KIY62244.1 - 3.6e-14 53.5 0.4 6.6e-14 52.7 0.4 1.4 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase Peptidase_M35 PF02102.15 KIY62244.1 - 2.7e-11 43.0 5.1 3.5e-11 42.6 5.1 1.1 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Reprolysin_4 PF13583.6 KIY62244.1 - 0.026 14.2 2.1 0.21 11.2 0.0 2.7 3 0 0 3 3 3 0 Metallo-peptidase family M12B Reprolysin-like Metallophos PF00149.28 KIY62245.1 - 3.3e-40 138.8 0.1 4.3e-40 138.4 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KIY62245.1 - 1e-21 77.1 0.5 2.1e-21 76.1 0.2 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Exo_endo_phos PF03372.23 KIY62247.1 - 1e-06 28.5 0.2 2.4e-06 27.3 0.2 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RED_N PF07808.13 KIY62248.1 - 2.3e-10 40.5 7.4 2.3e-10 40.5 7.4 3.1 2 1 0 2 2 2 1 RED-like protein N-terminal region Ribosomal_S21 PF01165.20 KIY62248.1 - 0.1 12.4 0.0 0.1 12.4 0.0 3.2 4 0 0 4 4 4 0 Ribosomal protein S21 DDE_Tnp_IS1595 PF12762.7 KIY62248.1 - 0.37 10.8 2.0 0.65 10.0 0.0 2.2 3 0 0 3 3 3 0 ISXO2-like transposase domain MBOAT PF03062.19 KIY62249.1 - 4.8e-38 131.4 23.5 1.2e-37 130.1 17.5 2.4 2 0 0 2 2 2 2 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 KIY62249.1 - 6.3e-05 23.2 5.4 0.00026 21.2 5.4 2.0 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family ATG27 PF09451.10 KIY62249.1 - 0.086 12.7 0.6 8.9 6.1 0.5 2.3 2 0 0 2 2 2 0 Autophagy-related protein 27 RNase_P_p30 PF01876.16 KIY62251.1 - 8.5e-37 126.7 0.0 1.2e-36 126.2 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit p30 DUF3664 PF12406.8 KIY62251.1 - 0.22 12.2 2.2 0.4 11.3 2.2 1.4 1 0 0 1 1 1 0 Surface protein zf-MYND PF01753.18 KIY62252.1 - 1.4e-08 34.6 17.0 3.1e-08 33.5 17.0 1.6 1 0 0 1 1 1 1 MYND finger SnoaL PF07366.12 KIY62252.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase GMC_oxred_N PF00732.19 KIY62253.1 - 3.7e-61 207.1 0.2 5.4e-61 206.5 0.2 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIY62253.1 - 3.8e-40 137.7 0.1 6.4e-40 137.0 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KIY62253.1 - 1.7e-05 24.0 0.1 2.8e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 KIY62253.1 - 1.8e-05 24.5 3.1 0.00056 19.6 2.6 2.7 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KIY62253.1 - 0.00059 19.0 0.7 0.0093 15.1 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KIY62253.1 - 0.00065 19.9 0.2 0.0021 18.3 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KIY62253.1 - 0.00089 18.6 0.1 0.002 17.4 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KIY62253.1 - 0.016 14.4 0.1 0.039 13.2 0.1 1.5 1 0 0 1 1 1 0 Thi4 family F-box-like PF12937.7 KIY62254.1 - 1.6e-07 31.1 0.3 3.4e-07 30.0 0.3 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY62254.1 - 4.8e-06 26.3 0.7 8.7e-06 25.5 0.7 1.4 1 0 0 1 1 1 1 F-box domain MIT PF04212.18 KIY62254.1 - 0.0043 17.1 0.1 0.0094 16.0 0.1 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain TPR_14 PF13428.6 KIY62254.1 - 0.0077 17.0 1.2 0.04 14.8 1.2 2.3 1 0 0 1 1 1 1 Tetratricopeptide repeat F-box_4 PF15966.5 KIY62254.1 - 0.023 14.6 0.0 0.042 13.7 0.0 1.3 1 0 0 1 1 1 0 F-box DnaJ PF00226.31 KIY62255.1 - 4.7e-24 84.3 0.0 7.8e-24 83.6 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain DUF1977 PF09320.11 KIY62255.1 - 2.6e-22 79.1 0.0 5e-22 78.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) Coiled-coil_56 PF09813.9 KIY62256.1 - 0.024 14.7 0.0 0.027 14.5 0.0 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 56 WD40 PF00400.32 KIY62257.1 - 1.6e-08 35.1 5.4 0.37 11.7 0.2 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat GMC_oxred_N PF00732.19 KIY62258.1 - 3.2e-60 204.0 0.0 5.4e-60 203.3 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIY62258.1 - 4.5e-30 105.1 0.0 8.6e-30 104.2 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KIY62258.1 - 7e-05 23.0 0.2 0.00018 21.7 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KIY62258.1 - 0.00011 21.4 0.2 0.0062 15.7 0.1 2.4 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 KIY62258.1 - 0.012 14.9 0.3 0.036 13.3 0.2 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIY62258.1 - 0.018 14.6 0.2 0.062 12.9 0.1 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIY62258.1 - 0.018 14.3 0.2 0.11 11.7 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KIY62258.1 - 0.023 13.8 0.3 0.036 13.1 0.3 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.14 KIY62258.1 - 0.11 11.1 0.1 0.19 10.4 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein ATP-synt_S1 PF05827.12 KIY62260.1 - 0.051 13.4 0.1 0.077 12.8 0.1 1.2 1 0 0 1 1 1 0 Vacuolar ATP synthase subunit S1 (ATP6S1) GMC_oxred_N PF00732.19 KIY62262.1 - 1.1e-51 176.0 0.0 1.7e-51 175.4 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIY62262.1 - 2.4e-28 99.5 0.0 4.6e-28 98.6 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KIY62262.1 - 0.026 13.6 0.0 0.065 12.3 0.0 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein DsbD_2 PF13386.6 KIY62263.1 - 0.026 14.5 1.4 0.026 14.5 1.4 2.3 2 0 0 2 2 2 0 Cytochrome C biogenesis protein transmembrane region NAD_binding_4 PF07993.12 KIY62264.1 - 2e-32 112.4 0.0 3e-32 111.8 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KIY62264.1 - 2.1e-27 95.8 0.1 2.5e-25 88.9 0.1 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Epimerase PF01370.21 KIY62264.1 - 1.9e-06 27.5 0.0 3.2e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KIY62264.1 - 0.00012 22.4 0.1 0.0006 20.1 0.1 2.3 1 1 0 1 1 1 1 Phosphopantetheine attachment site KR PF08659.10 KIY62264.1 - 0.0057 16.6 0.0 0.033 14.1 0.0 2.2 1 1 0 1 1 1 1 KR domain F-box-like PF12937.7 KIY62265.1 - 3e-05 23.8 0.2 4.7e-05 23.2 0.2 1.3 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY62265.1 - 4.9e-05 23.1 0.1 8.1e-05 22.4 0.1 1.3 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KIY62265.1 - 0.012 15.5 0.0 0.014 15.2 0.0 1.2 1 0 0 1 1 1 0 F-box Cupin_8 PF13621.6 KIY62268.1 - 0.054 13.2 0.1 0.18 11.5 0.1 1.9 1 1 0 1 1 1 0 Cupin-like domain Cupin_4 PF08007.12 KIY62268.1 - 0.076 12.5 0.1 0.23 10.9 0.0 1.7 2 0 0 2 2 2 0 Cupin superfamily protein JmjC PF02373.22 KIY62268.1 - 0.08 13.4 0.0 0.23 11.9 0.0 1.8 1 0 0 1 1 1 0 JmjC domain, hydroxylase ubiquitin PF00240.23 KIY62273.1 - 6.4e-36 121.9 1.4 3.2e-25 87.7 0.2 2.3 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.8 KIY62273.1 - 6.3e-14 51.6 1.5 4.1e-09 36.1 0.4 2.1 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 KIY62273.1 - 0.0062 16.4 0.3 1.4 8.9 0.0 2.2 2 0 0 2 2 2 2 TANK binding kinase 1 ubiquitin-like domain MCR_D PF02505.14 KIY62273.1 - 0.079 12.8 0.1 0.11 12.4 0.1 1.2 1 0 0 1 1 1 0 Methyl-coenzyme M reductase operon protein D Ubiquitin_4 PF18036.1 KIY62273.1 - 0.12 12.4 1.5 9.9 6.3 0.2 2.8 2 1 1 3 3 3 0 Ubiquitin-like domain DUF2870 PF11069.8 KIY62273.1 - 0.16 12.4 0.0 1.7 9.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) PASTA PF03793.19 KIY62276.1 - 0.075 12.9 0.4 0.41 10.5 0.2 2.2 2 0 0 2 2 2 0 PASTA domain NPL PF17800.1 KIY62278.1 - 2.7e-05 24.7 0.0 3.4e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Nucleoplasmin-like domain KSHV_K1 PF11049.8 KIY62279.1 - 0.012 15.5 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 Glycoprotein K1 of Kaposi's sarcoma-associated herpes virus Transposase_21 PF02992.14 KIY62281.1 - 5.4e-07 29.1 0.0 6.8e-07 28.7 0.0 1.1 1 0 0 1 1 1 1 Transposase family tnp2 DUF1258 PF06869.12 KIY62281.1 - 6.9e-07 29.0 0.1 1.1e-06 28.4 0.1 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1258) Plavaka PF18759.1 KIY62281.1 - 2.1e-05 23.9 0.4 2.6e-05 23.6 0.4 1.1 1 0 0 1 1 1 1 Plavaka transposase DUF4218 PF13960.6 KIY62282.1 - 0.13 11.9 0.0 0.23 11.1 0.0 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4218) DDE_1 PF03184.19 KIY62283.1 - 9.9e-08 31.8 0.0 1.1e-06 28.5 0.0 2.3 2 0 0 2 2 2 1 DDE superfamily endonuclease Borrelia_P83 PF05262.11 KIY62283.1 - 0.0037 15.8 0.6 0.0053 15.3 0.6 1.2 1 0 0 1 1 1 1 Borrelia P83/100 protein RNA_polI_A34 PF08208.11 KIY62283.1 - 0.014 15.5 1.6 0.027 14.6 1.6 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Oxidored_FMN PF00724.20 KIY62284.1 - 6.3e-90 301.9 0.0 7.2e-90 301.7 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family RdRP PF05183.12 KIY62286.1 - 1.3e-95 321.3 0.0 2.1e-95 320.6 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase Cyclin_N PF00134.23 KIY62288.1 - 0.0038 17.0 0.0 0.043 13.6 0.0 2.2 1 1 0 1 1 1 1 Cyclin, N-terminal domain DHquinase_I PF01487.15 KIY62289.1 - 8.7e-48 163.6 0.0 1.7e-47 162.6 0.0 1.5 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 KIY62289.1 - 3e-32 111.9 0.0 5.9e-32 111.0 0.0 1.5 1 0 0 1 1 1 1 Shikimate kinase Shikimate_dh_N PF08501.11 KIY62289.1 - 2.7e-25 88.4 0.0 5.6e-25 87.4 0.0 1.6 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 KIY62289.1 - 2.6e-08 33.5 0.0 5.2e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 KIY62289.1 - 4e-08 33.4 0.0 7.9e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AAA_33 PF13671.6 KIY62289.1 - 2.1e-05 24.7 0.0 0.00023 21.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain Sacchrp_dh_NADP PF03435.18 KIY62289.1 - 0.005 17.1 0.9 0.017 15.3 0.0 2.4 3 0 0 3 3 3 1 Saccharopine dehydrogenase NADP binding domain AAA_18 PF13238.6 KIY62289.1 - 0.029 14.9 0.0 0.13 12.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KIY62289.1 - 0.14 12.6 0.0 0.37 11.2 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain Cytidylate_kin2 PF13189.6 KIY62289.1 - 0.15 12.2 0.1 2.3 8.3 0.0 2.3 2 0 0 2 2 2 0 Cytidylate kinase-like family AAA_14 PF13173.6 KIY62289.1 - 0.18 11.8 0.0 0.35 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF1996 PF09362.10 KIY62290.1 - 1.5e-82 277.2 1.0 1.7e-82 276.9 1.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) DUF3723 PF12520.8 KIY62292.1 - 0.048 12.3 0.0 0.078 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3723) Ndc1_Nup PF09531.10 KIY62293.1 - 0.19 10.4 1.5 0.26 9.9 1.5 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DAG_kinase_N PF14513.6 KIY62293.1 - 0.25 11.5 2.6 0.18 12.0 1.1 1.6 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus YL1 PF05764.13 KIY62293.1 - 0.76 9.8 25.8 1.5 8.9 13.2 2.2 2 0 0 2 2 2 0 YL1 nuclear protein Nucleo_P87 PF07267.11 KIY62293.1 - 1.1 8.0 20.3 0.048 12.5 3.2 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 Helicase_C PF00271.31 KIY62294.1 - 8.8e-08 32.5 0.0 1.7e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Glyco_hydro_18 PF00704.28 KIY62296.1 - 2.2e-73 247.7 0.0 2.5e-73 247.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 zf-H2C2_2 PF13465.6 KIY62297.1 - 0.00057 20.2 0.5 0.00057 20.2 0.5 2.8 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.26 KIY62297.1 - 0.017 15.5 7.4 0.053 14.0 0.1 2.7 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIY62297.1 - 0.45 11.5 6.7 1.4 10.0 0.1 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger F-box-like PF12937.7 KIY62298.1 - 0.0067 16.3 1.7 0.025 14.5 1.7 2.0 1 1 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KIY62298.1 - 0.046 14.2 0.1 1.2 9.6 0.0 3.1 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) F-box PF00646.33 KIY62298.1 - 0.066 13.1 0.4 0.066 13.1 0.4 2.0 2 0 0 2 2 2 0 F-box domain OrsD PF12013.8 KIY62300.1 - 9.7e-05 22.8 0.0 0.00037 20.9 0.0 2.1 1 0 0 1 1 1 1 Orsellinic acid/F9775 biosynthesis cluster protein D zf-H2C2_5 PF13909.6 KIY62300.1 - 0.0027 17.4 1.5 0.0027 17.4 1.5 2.3 3 0 0 3 3 3 1 C2H2-type zinc-finger domain DUF5332 PF17266.2 KIY62300.1 - 0.51 10.0 4.7 0.81 9.4 1.5 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5332) Transposase_21 PF02992.14 KIY62301.1 - 0.017 14.4 0.0 0.028 13.7 0.0 1.3 1 0 0 1 1 1 0 Transposase family tnp2 DUF4218 PF13960.6 KIY62301.1 - 0.023 14.3 0.1 0.041 13.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) Ndc1_Nup PF09531.10 KIY62303.1 - 0.069 11.8 5.9 0.1 11.2 5.9 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SOG2 PF10428.9 KIY62303.1 - 1 8.5 21.1 2.1 7.4 21.1 1.4 1 0 0 1 1 1 0 RAM signalling pathway protein SPX PF03105.19 KIY62303.1 - 3.6 7.4 17.6 5.7 6.7 17.6 1.3 1 0 0 1 1 1 0 SPX domain FliD_C PF07195.12 KIY62304.1 - 0.89 8.9 7.4 0.03 13.8 1.4 1.6 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus DHHW PF14286.6 KIY62304.1 - 4.3 6.5 6.1 1.8 7.8 3.6 1.5 2 0 0 2 2 2 0 DHHW protein ADK PF00406.22 KIY62305.1 - 4.9e-08 33.2 0.2 7.8e-08 32.6 0.2 1.3 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KIY62305.1 - 0.0064 16.9 0.3 0.011 16.2 0.2 1.4 2 0 0 2 2 2 1 AAA domain ADK PF00406.22 KIY62306.1 - 4.3e-30 104.8 0.1 7.6e-30 104.0 0.1 1.4 1 1 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KIY62306.1 - 3.3e-22 79.4 0.0 5.2e-22 78.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KIY62306.1 - 0.0045 17.5 0.0 0.0061 17.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 KIY62306.1 - 0.03 14.0 0.0 0.045 13.4 0.0 1.3 1 0 0 1 1 1 0 Thymidylate kinase Ploopntkinase3 PF18751.1 KIY62306.1 - 0.037 13.9 0.0 0.068 13.1 0.0 1.5 1 1 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_33 PF13671.6 KIY62306.1 - 0.093 12.9 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain Molybdopterin PF00384.22 KIY62308.1 - 2e-71 241.2 0.0 1e-34 120.2 0.0 2.3 1 1 1 2 2 2 2 Molybdopterin oxidoreductase Fer2_4 PF13510.6 KIY62308.1 - 2.3e-19 69.2 0.2 6e-19 67.9 0.2 1.7 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.9 KIY62308.1 - 1.7e-17 62.6 0.2 1.7e-17 62.6 0.2 2.0 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region NADH_dhqG_C PF09326.11 KIY62308.1 - 1.7e-14 54.2 0.0 3.8e-14 53.1 0.0 1.6 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal Fer2 PF00111.27 KIY62308.1 - 5.6e-09 35.8 0.4 5.6e-09 35.8 0.4 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.22 KIY62308.1 - 0.075 12.8 0.0 2.2 8.0 0.0 2.5 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Fer4 PF00037.27 KIY62308.1 - 0.094 12.6 1.1 4.8 7.2 0.3 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain DnaJ_C PF01556.18 KIY62309.1 - 1.8e-41 141.7 0.5 2.4e-41 141.3 0.5 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KIY62309.1 - 3.3e-20 72.0 1.5 6.8e-20 71.0 0.9 1.8 2 0 0 2 2 2 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KIY62309.1 - 9.7e-17 61.1 18.3 1.9e-16 60.1 18.3 1.5 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KIY62309.1 - 1.7e-05 24.7 14.9 0.0014 18.6 2.2 2.5 1 1 1 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 KIY62309.1 - 0.26 11.3 10.1 1.1 9.3 0.8 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 KIY62309.1 - 4.8 7.3 9.8 2e+02 2.1 9.8 2.3 1 1 0 1 1 1 0 Double zinc ribbon Lar_restr_allev PF14354.6 KIY62309.1 - 8 6.9 7.8 22 5.5 4.7 2.9 1 1 1 2 2 2 0 Restriction alleviation protein Lar 5-FTHF_cyc-lig PF01812.20 KIY62310.1 - 4.1e-43 147.4 0.0 4.7e-43 147.2 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Ribosomal_L7Ae PF01248.26 KIY62311.1 - 1.8e-22 78.8 1.5 3.1e-22 78.1 1.3 1.5 1 1 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Efg1 PF10153.9 KIY62311.1 - 0.13 12.6 2.4 0.26 11.6 0.3 2.3 2 0 0 2 2 2 0 rRNA-processing protein Efg1 zf-MYND PF01753.18 KIY62312.1 - 1.2e-09 38.1 7.4 2.4e-09 37.1 7.4 1.5 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.18 KIY62313.1 - 6.9e-09 35.7 6.7 1.3e-08 34.8 6.7 1.4 1 0 0 1 1 1 1 MYND finger DASH_Ask1 PF08655.10 KIY62314.1 - 5.6e-24 83.8 0.4 9.1e-24 83.1 0.4 1.3 1 0 0 1 1 1 1 DASH complex subunit Ask1 Glyco_transf_17 PF04724.13 KIY62315.1 - 1.4e-136 455.2 0.0 1.7e-136 454.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 17 zf-RVT PF13966.6 KIY62317.1 - 2.3e-08 34.6 0.3 8.7e-08 32.8 0.0 2.1 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase fn1 PF00039.18 KIY62317.1 - 0.24 11.6 2.3 0.6 10.4 1.6 2.1 2 0 0 2 2 2 0 Fibronectin type I domain RNase_H PF00075.24 KIY62318.1 - 2.8e-07 30.8 0.0 3.1e-07 30.7 0.0 1.0 1 0 0 1 1 1 1 RNase H DDE_1 PF03184.19 KIY62319.1 - 8.3e-05 22.3 0.2 0.00013 21.7 0.0 1.4 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_3 PF13358.6 KIY62319.1 - 0.011 15.5 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 0 DDE superfamily endonuclease PP28 PF10252.9 KIY62325.1 - 1e-24 86.8 12.7 1e-24 86.8 12.7 2.7 3 0 0 3 3 3 2 Casein kinase substrate phosphoprotein PP28 Complex1_LYR PF05347.15 KIY62326.1 - 1.1e-08 35.0 0.3 2.3e-08 33.9 0.3 1.6 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KIY62326.1 - 8.7e-05 23.2 0.1 0.0001 23.0 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like DUF1772 PF08592.11 KIY62326.1 - 0.091 13.1 0.1 0.11 12.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) Nrap_D5 PF17406.2 KIY62326.1 - 0.093 12.5 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 Nrap protein PAP/OAS1-like domain 5 SET PF00856.28 KIY62328.1 - 6.3e-17 62.5 5.7 4.2e-16 59.8 0.0 3.4 2 1 0 2 2 2 1 SET domain SRI PF08236.11 KIY62328.1 - 1.1e-14 54.3 6.6 1.1e-14 54.3 6.6 2.4 2 0 0 2 2 2 1 SRI (Set2 Rpb1 interacting) domain AWS PF17907.1 KIY62328.1 - 5.7e-12 45.5 11.4 5.7e-12 45.5 11.4 1.8 2 0 0 2 2 2 1 AWS domain RRM_1 PF00076.22 KIY62329.1 - 4.2e-05 23.3 0.1 5.9e-05 22.8 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET_assoc PF11767.8 KIY62329.1 - 0.083 12.5 0.1 0.12 12.0 0.1 1.2 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated F-box-like PF12937.7 KIY62330.1 - 3.6e-07 30.0 0.7 0.001 18.9 0.1 2.8 2 0 0 2 2 2 2 F-box-like LRR_4 PF12799.7 KIY62330.1 - 0.035 14.6 0.0 1.3 9.5 0.1 2.8 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) F-box PF00646.33 KIY62330.1 - 3.9 7.5 6.5 5.2 7.1 0.0 3.4 4 0 0 4 4 4 0 F-box domain Baculo_PEP_C PF04513.12 KIY62331.1 - 0.12 12.5 0.3 0.24 11.4 0.3 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus AcylCoA_dehyd_C PF12186.8 KIY62333.1 - 0.1 12.7 0.3 0.23 11.6 0.3 1.5 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase C terminal Spc7 PF08317.11 KIY62333.1 - 0.11 11.4 0.3 0.17 10.7 0.3 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4200 PF13863.6 KIY62334.1 - 0.027 14.9 1.3 0.041 14.3 1.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Apolipoprotein PF01442.18 KIY62334.1 - 0.032 14.1 0.2 0.046 13.6 0.2 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain CENP-Q PF13094.6 KIY62334.1 - 0.078 13.2 0.2 0.11 12.7 0.2 1.2 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Syntaxin-6_N PF09177.11 KIY62334.1 - 0.13 12.9 0.4 0.31 11.6 0.4 1.6 1 1 0 1 1 1 0 Syntaxin 6, N-terminal CMV_1a PF12467.8 KIY62334.1 - 0.28 11.5 0.1 0.28 11.5 0.1 2.3 2 1 0 2 2 2 0 Cucumber mosaic virus 1a protein family F-box-like PF12937.7 KIY62338.1 - 2.5e-05 24.1 0.1 0.0001 22.1 0.1 2.1 1 1 0 1 1 1 1 F-box-like LRR_9 PF14580.6 KIY62338.1 - 0.15 11.5 0.2 0.33 10.5 0.2 1.5 1 0 0 1 1 1 0 Leucine-rich repeat GATase_6 PF13522.6 KIY62339.1 - 7.8e-13 48.8 0.0 1.7e-12 47.7 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KIY62339.1 - 9.5e-11 41.7 0.0 1.8e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 KIY62339.1 - 5.7e-10 38.9 0.1 9.4e-10 38.2 0.1 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 KIY62339.1 - 9.9e-08 31.2 0.0 4.9e-06 25.7 0.0 2.2 2 0 0 2 2 2 2 Glutamine amidotransferases class-II Gti1_Pac2 PF09729.9 KIY62340.1 - 3.2e-30 105.6 1.4 2.2e-28 99.6 0.4 2.2 1 1 1 2 2 2 2 Gti1/Pac2 family Elongin_A PF06881.11 KIY62341.1 - 2.8e-15 56.7 0.4 4.5e-15 56.1 0.4 1.3 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A WD40 PF00400.32 KIY62342.1 - 6.9e-26 90.0 20.0 7.4e-07 29.8 0.1 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY62342.1 - 1.6e-08 34.7 0.4 0.17 12.2 0.0 4.3 3 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Dynamin_M PF01031.20 KIY62344.1 - 1.4e-37 129.4 0.0 3.7e-37 128.1 0.0 1.6 1 1 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 KIY62344.1 - 1.3e-27 96.9 0.1 3e-27 95.7 0.1 1.7 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 KIY62344.1 - 4.7e-05 23.4 1.1 0.00032 20.7 0.2 2.8 3 1 0 3 3 3 1 50S ribosome-binding GTPase ABC_tran PF00005.27 KIY62344.1 - 0.025 15.1 0.0 0.067 13.7 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 KIY62344.1 - 0.041 13.6 0.1 0.19 11.5 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_16 PF13191.6 KIY62344.1 - 0.077 13.4 0.2 0.54 10.6 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain RasGEF_N_2 PF14663.6 KIY62344.1 - 0.083 13.3 0.5 0.3 11.5 0.2 2.0 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain FeoB_N PF02421.18 KIY62344.1 - 0.15 11.6 0.1 3.9 7.0 0.0 2.9 3 0 0 3 3 3 0 Ferrous iron transport protein B Atg14 PF10186.9 KIY62346.1 - 1.2e-41 142.9 3.9 7.8e-27 94.2 0.0 2.1 2 0 0 2 2 2 2 Vacuolar sorting 38 and autophagy-related subunit 14 LMP PF04778.12 KIY62346.1 - 0.16 11.8 0.3 0.27 11.1 0.3 1.2 1 0 0 1 1 1 0 LMP repeated region ICMT PF04140.14 KIY62348.1 - 1e-13 51.5 0.0 6.3e-13 49.0 0.0 2.1 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KIY62348.1 - 5.1e-12 46.1 0.7 5.1e-12 46.1 0.7 2.5 2 1 0 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 KIY62348.1 - 6e-05 22.0 0.1 8.7e-05 21.5 0.1 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Mito_carr PF00153.27 KIY62348.1 - 0.092 12.7 0.2 0.27 11.2 0.1 1.7 1 1 0 1 1 1 0 Mitochondrial carrier protein DUF973 PF06157.11 KIY62348.1 - 0.2 10.7 0.3 0.55 9.2 0.2 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF973) Lenti_VIF_2 PF07401.12 KIY62349.1 - 0.078 12.3 0.1 0.11 11.8 0.1 1.2 1 0 0 1 1 1 0 Bovine Lentivirus VIF protein DUF2183 PF09949.9 KIY62350.1 - 5.9e-25 87.5 0.1 1.4e-24 86.3 0.1 1.6 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) LNS2 PF08235.13 KIY62350.1 - 0.013 15.0 0.0 0.021 14.3 0.0 1.2 1 0 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) Metallophos PF00149.28 KIY62351.1 - 9.3e-12 45.9 0.1 1.4e-11 45.3 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KIY62351.1 - 5.4e-09 36.4 0.1 5.5e-08 33.2 0.1 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Jiv90 PF14901.6 KIY62351.1 - 0.1 12.8 0.0 0.57 10.4 0.0 2.1 2 0 0 2 2 2 0 Cleavage inducing molecular chaperone SPT16 PF08644.11 KIY62352.1 - 2.2e-56 190.3 4.7 4e-56 189.4 0.3 2.7 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.6 KIY62352.1 - 7.7e-39 133.1 0.0 1.8e-38 131.8 0.0 1.7 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 KIY62352.1 - 1.2e-22 80.7 0.0 2e-22 79.9 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 KIY62352.1 - 2e-15 56.9 0.1 2.4e-14 53.5 0.0 2.5 2 0 0 2 2 2 1 Histone chaperone Rttp106-like Dynamin_M PF01031.20 KIY62353.1 - 1.1e-32 113.5 0.0 2.5e-32 112.3 0.0 1.6 1 1 1 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 KIY62353.1 - 2.5e-24 86.2 0.0 1.5e-23 83.7 0.0 2.3 2 1 0 2 2 2 1 Dynamin family GED PF02212.18 KIY62353.1 - 4.8e-08 33.0 0.5 1.3e-07 31.7 0.1 2.0 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KIY62353.1 - 8.8e-05 22.6 0.0 0.0011 19.0 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KIY62353.1 - 0.0026 18.2 0.0 0.011 16.1 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain Apolipoprotein PF01442.18 KIY62353.1 - 0.19 11.6 0.1 0.19 11.6 0.1 2.5 3 0 0 3 3 3 0 Apolipoprotein A1/A4/E domain p450 PF00067.22 KIY62356.1 - 2.7e-67 227.5 0.0 4.4e-67 226.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 UBX PF00789.20 KIY62357.1 - 7.5e-11 42.1 0.0 1.4e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 KIY62357.1 - 1.7e-05 24.5 0.0 3e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain PGA2 PF07543.12 KIY62357.1 - 0.019 14.9 3.9 0.037 14.0 3.9 1.4 1 0 0 1 1 1 0 Protein trafficking PGA2 p450 PF00067.22 KIY62358.1 - 8.6e-66 222.6 0.0 1.3e-65 222.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PAP_PilO PF06864.12 KIY62358.1 - 0.011 14.6 0.0 0.017 14.0 0.0 1.2 1 0 0 1 1 1 0 Pilin accessory protein (PilO) FAD_binding_3 PF01494.19 KIY62359.1 - 4.1e-21 75.6 0.1 8.7e-10 38.4 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KIY62359.1 - 0.00027 21.1 0.5 0.00064 19.9 0.5 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KIY62359.1 - 0.00065 19.0 0.4 0.029 13.6 0.4 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KIY62359.1 - 0.016 14.1 0.0 0.05 12.4 0.0 1.8 2 0 0 2 2 2 0 Tryptophan halogenase SE PF08491.10 KIY62359.1 - 0.19 10.7 0.0 0.34 9.9 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase DAO PF01266.24 KIY62359.1 - 0.24 11.0 1.2 0.39 10.3 1.2 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase SseC PF04888.12 KIY62361.1 - 1.7 8.2 7.4 2 7.9 7.4 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family SLATT_fungal PF18142.1 KIY62362.1 - 4.6e-34 117.0 0.3 6.3e-34 116.5 0.3 1.2 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain Proteasome PF00227.26 KIY62363.1 - 1.7e-44 151.6 0.3 7.2e-44 149.6 0.3 1.8 1 1 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KIY62363.1 - 1.1e-14 53.7 0.3 2.1e-14 52.9 0.3 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature zf-C2H2 PF00096.26 KIY62367.1 - 3.9e-14 52.2 10.7 1.9e-07 31.2 2.1 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIY62367.1 - 1.4e-11 44.2 7.5 9.3e-06 26.1 1.2 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KIY62367.1 - 1.7e-10 40.8 11.4 1.3e-06 28.5 0.2 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-met PF12874.7 KIY62367.1 - 1.1e-06 28.8 1.6 7.6e-05 23.0 0.2 2.3 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 KIY62367.1 - 6.2e-06 26.0 10.5 0.003 17.4 1.3 2.7 2 1 0 2 2 2 2 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.8 KIY62367.1 - 8.3e-06 26.0 0.5 0.0023 18.2 0.0 2.2 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KIY62367.1 - 1.1e-05 25.2 2.6 0.00014 21.7 0.2 2.4 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KIY62367.1 - 0.0075 16.0 3.7 0.97 9.2 1.5 2.3 2 0 0 2 2 2 2 zinc-finger C2H2-type Zn_ribbon_SprT PF17283.2 KIY62367.1 - 0.015 15.2 3.6 0.48 10.4 0.7 2.3 1 1 1 2 2 2 0 SprT-like zinc ribbon domain Ogr_Delta PF04606.12 KIY62367.1 - 0.037 14.0 2.6 0.051 13.6 2.6 1.2 1 0 0 1 1 1 0 Ogr/Delta-like zinc finger zf-Di19 PF05605.12 KIY62367.1 - 0.056 13.7 1.7 3.5 8.0 0.2 2.1 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 KIY62367.1 - 0.06 13.7 1.1 0.49 10.7 0.1 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) DUF3268 PF11672.8 KIY62367.1 - 0.069 13.5 0.2 0.075 13.4 0.2 1.1 1 0 0 1 1 1 0 zinc-finger-containing domain CpXC PF14353.6 KIY62367.1 - 0.073 13.1 0.5 9.5 6.3 0.1 2.0 1 1 1 2 2 2 0 CpXC protein IBR PF01485.21 KIY62367.1 - 0.11 12.7 2.2 0.54 10.5 0.2 2.1 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain zf-LYAR PF08790.11 KIY62367.1 - 0.21 11.5 2.0 7.1 6.6 0.0 2.8 2 1 0 2 2 2 0 LYAR-type C2HC zinc finger ADK_lid PF05191.14 KIY62367.1 - 0.32 11.0 5.4 0.75 9.8 0.5 2.2 2 0 0 2 2 2 0 Adenylate kinase, active site lid FYVE PF01363.21 KIY62367.1 - 0.32 11.1 5.5 1 9.6 0.9 2.1 1 1 1 2 2 2 0 FYVE zinc finger zf-H2C2_5 PF13909.6 KIY62367.1 - 1.4 8.7 12.3 1.4 8.7 0.2 3.1 3 0 0 3 3 3 0 C2H2-type zinc-finger domain DUF4281 PF14108.6 KIY62368.1 - 0.006 16.9 1.3 0.0084 16.5 0.1 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF4281) RIFIN PF02009.16 KIY62368.1 - 0.2 11.6 0.1 0.25 11.2 0.1 1.1 1 0 0 1 1 1 0 Rifin F-box-like PF12937.7 KIY62370.1 - 0.00061 19.6 0.8 0.0021 17.9 0.8 2.0 1 1 0 1 1 1 1 F-box-like F-box-like PF12937.7 KIY62372.1 - 0.00017 21.4 8.0 0.00033 20.5 4.7 3.0 2 1 0 2 2 2 1 F-box-like LRR_4 PF12799.7 KIY62372.1 - 0.044 14.2 3.9 7.9 7.0 0.1 4.4 5 1 1 6 6 6 0 Leucine Rich repeats (2 copies) F-box PF00646.33 KIY62372.1 - 3.5 7.6 6.8 7.9 6.5 0.9 3.4 3 0 0 3 3 3 0 F-box domain Methyltransf_10 PF05971.12 KIY62376.1 - 2.5e-67 227.4 0.0 3.9e-67 226.7 0.0 1.3 1 0 0 1 1 1 1 RNA methyltransferase MTS PF05175.14 KIY62376.1 - 8.7e-06 25.4 0.0 1.8e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 KIY62376.1 - 0.0028 17.1 0.0 0.0043 16.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) TrmK PF04816.12 KIY62376.1 - 0.12 11.9 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 tRNA (adenine(22)-N(1))-methyltransferase RRM_1 PF00076.22 KIY62377.1 - 3.5e-17 62.0 0.0 4.8e-17 61.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KIY62377.1 - 0.0072 15.9 0.0 0.0097 15.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LRR_4 PF12799.7 KIY62378.1 - 9.2e-10 38.6 3.2 0.3 11.6 1.2 6.0 5 1 1 6 6 6 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KIY62378.1 - 2.3e-05 24.1 7.9 0.63 10.2 0.0 6.1 6 1 0 6 6 6 3 Leucine Rich repeat DUF5553 PF17707.1 KIY62378.1 - 0.089 12.2 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5553) LRR_8 PF13855.6 KIY62378.1 - 0.12 12.1 7.0 3.6 7.4 0.7 5.5 7 2 0 7 7 7 0 Leucine rich repeat TPT PF03151.16 KIY62379.1 - 1.9e-15 57.0 26.2 2.3e-15 56.7 26.2 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KIY62379.1 - 0.00036 20.7 37.7 0.0016 18.6 10.5 2.4 2 1 0 2 2 2 2 EamA-like transporter family SLATT_4 PF18186.1 KIY62379.1 - 3.3 7.3 4.7 0.91 9.1 1.1 1.9 1 1 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 4 Mre11_DNA_bind PF04152.14 KIY62380.1 - 4.8e-47 160.4 0.7 4.8e-47 160.4 0.7 2.2 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 KIY62380.1 - 1.2e-12 48.8 0.3 1.9e-12 48.1 0.3 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KIY62380.1 - 1.1e-05 25.7 0.0 0.00015 22.0 0.0 2.7 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain DNA_pol3_a_NII PF11490.8 KIY62380.1 - 1.4 8.8 4.4 0.64 9.9 0.9 2.3 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus II EST1_DNA_bind PF10373.9 KIY62381.1 - 8.9e-24 84.4 0.0 1.6e-23 83.6 0.0 1.4 1 1 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.9 KIY62381.1 - 2e-23 83.5 0.0 4.3e-23 82.5 0.0 1.6 1 0 0 1 1 1 1 Telomerase activating protein Est1 TPR_2 PF07719.17 KIY62381.1 - 0.19 12.0 0.4 0.58 10.4 0.4 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF4100 PF13352.6 KIY62382.1 - 0.06 13.1 0.5 0.084 12.6 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4100) BRAP2 PF07576.12 KIY62383.1 - 5.4e-30 103.5 0.0 9.1e-30 102.8 0.0 1.3 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 KIY62383.1 - 2.4e-19 69.4 5.2 5.8e-19 68.2 5.2 1.6 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 KIY62383.1 - 2.2e-08 34.3 9.5 2.2e-08 34.3 9.5 2.0 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KIY62383.1 - 5.7e-06 26.1 9.4 5.7e-06 26.1 9.4 2.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KIY62383.1 - 1.7e-05 24.5 4.9 4.7e-05 23.0 4.9 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 KIY62383.1 - 2.3e-05 24.6 6.1 6.6e-05 23.1 6.1 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KIY62383.1 - 3.1e-05 23.7 7.7 3.1e-05 23.7 7.7 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KIY62383.1 - 3.9e-05 23.6 3.3 3.9e-05 23.6 3.3 2.1 2 1 0 2 2 1 1 RING-type zinc-finger Macoilin PF09726.9 KIY62383.1 - 9.4e-05 21.2 1.9 0.00011 20.9 1.9 1.1 1 0 0 1 1 1 1 Macoilin family zf-C3HC4_3 PF13920.6 KIY62383.1 - 0.0008 19.2 6.7 0.0008 19.2 6.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.22 KIY62383.1 - 0.0015 18.3 0.0 0.0033 17.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4407 PF14362.6 KIY62383.1 - 0.0033 16.8 7.5 0.0051 16.2 7.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) zf-RING_5 PF14634.6 KIY62383.1 - 0.0035 17.3 6.7 0.0035 17.3 6.7 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KIY62383.1 - 0.0039 17.2 2.9 0.0084 16.1 2.9 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Rootletin PF15035.6 KIY62383.1 - 0.027 14.5 18.4 0.054 13.5 18.4 1.4 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion zf-UBP_var PF17807.1 KIY62383.1 - 0.046 13.5 0.7 0.093 12.5 0.7 1.5 1 0 0 1 1 1 0 Variant UBP zinc finger zf-RING_4 PF14570.6 KIY62383.1 - 0.047 13.5 6.2 0.11 12.3 6.2 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain HDOD PF08668.12 KIY62383.1 - 0.12 11.8 0.7 0.19 11.2 0.7 1.2 1 0 0 1 1 1 0 HDOD domain DUF2968 PF11180.8 KIY62383.1 - 1.4 8.5 18.7 0.71 9.5 12.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) Golgin_A5 PF09787.9 KIY62383.1 - 1.8 8.0 17.7 2.6 7.4 17.7 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 Fib_alpha PF08702.10 KIY62383.1 - 3 8.0 7.0 12 6.1 1.2 2.5 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Tho2 PF11262.8 KIY62383.1 - 4 6.5 7.2 5.9 6.0 7.2 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Atg14 PF10186.9 KIY62383.1 - 4 6.4 11.5 8.7 5.3 11.5 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Laminin_II PF06009.12 KIY62383.1 - 6.6 6.8 9.7 5.4 7.0 3.2 2.4 1 1 1 2 2 2 0 Laminin Domain II Prok-RING_4 PF14447.6 KIY62383.1 - 6.9 6.6 22.0 1.4 8.8 11.4 3.2 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 DBR1 PF05011.13 KIY62384.1 - 4.4e-37 127.6 0.1 8e-37 126.8 0.1 1.4 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain BBE PF08031.12 KIY62385.1 - 1.8e-07 31.2 0.0 2.1e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 Berberine and berberine like ALO PF04030.14 KIY62385.1 - 0.051 13.4 0.0 0.052 13.3 0.0 1.0 1 0 0 1 1 1 0 D-arabinono-1,4-lactone oxidase F-box-like PF12937.7 KIY62386.1 - 5.7e-09 35.7 1.7 1.3e-08 34.6 1.7 1.6 1 0 0 1 1 1 1 F-box-like Pectate_lyase PF03211.13 KIY62387.1 - 1.4e-84 282.7 2.1 1.7e-84 282.4 2.1 1.0 1 0 0 1 1 1 1 Pectate lyase Glyoxalase_3 PF13468.6 KIY62388.1 - 0.17 12.0 0.2 0.66 10.1 0.2 1.8 1 1 1 2 2 2 0 Glyoxalase-like domain JAB PF01398.21 KIY62389.1 - 8.6e-30 103.1 0.2 1.8e-29 102.1 0.2 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CSN5_C PF18323.1 KIY62389.1 - 3.5e-29 101.6 4.8 5.5e-29 100.9 3.9 1.8 2 0 0 2 2 2 1 Cop9 signalosome subunit 5 C-terminal domain Prok-JAB PF14464.6 KIY62389.1 - 2.6e-05 24.0 0.0 4.7e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain TFB6 PF17110.5 KIY62389.1 - 0.019 14.7 0.6 0.034 13.9 0.6 1.4 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH DUF4404 PF14357.6 KIY62389.1 - 0.13 12.9 0.6 0.25 12.0 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) Sox_N PF12444.8 KIY62389.1 - 0.41 11.8 1.9 0.97 10.6 1.9 1.6 1 0 0 1 1 1 0 Sox developmental protein N terminal Zn_clus PF00172.18 KIY62390.1 - 4.2e-06 26.8 6.8 8.1e-06 25.9 6.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box-like PF12937.7 KIY62391.1 - 6.6e-09 35.5 0.8 6.6e-09 35.5 0.8 2.7 3 0 0 3 3 3 1 F-box-like Clr2_transil PF16761.5 KIY62394.1 - 1.8e-15 57.5 1.3 3.1e-15 56.7 1.3 1.4 1 0 0 1 1 1 1 Transcription-silencing protein, cryptic loci regulator Clr2 Transposase_21 PF02992.14 KIY62395.1 - 0.00024 20.4 0.0 0.00036 19.8 0.0 1.4 1 1 0 1 1 1 1 Transposase family tnp2 eIF-3c_N PF05470.12 KIY62397.1 - 0.51 8.6 3.9 0.085 11.2 0.3 1.5 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Cwf_Cwc_15 PF04889.12 KIY62397.1 - 0.72 9.5 13.1 3 7.5 3.9 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Asp PF00026.23 KIY62398.1 - 3.9e-19 69.2 0.7 4e-08 33.0 0.0 3.2 2 1 0 2 2 2 2 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 KIY62398.1 - 1.9e-09 38.0 0.0 0.0053 17.4 0.1 3.2 2 2 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 KIY62398.1 - 6.4e-07 29.8 0.0 0.1 13.2 0.0 3.7 3 1 0 3 3 3 3 gag-polyprotein putative aspartyl protease TAXi_N PF14543.6 KIY62398.1 - 0.011 16.0 0.1 0.32 11.2 0.1 2.3 1 1 1 2 2 2 0 Xylanase inhibitor N-terminal LPMO_10 PF03067.15 KIY62399.1 - 2.2e-10 41.5 0.4 2.2e-10 41.5 0.4 1.7 2 0 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading CBM_21 PF03370.13 KIY62400.1 - 1.3e-23 83.4 0.0 2.1e-23 82.6 0.0 1.4 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 KIY62400.1 - 3.8e-09 37.0 0.4 9.5e-09 35.7 0.4 1.6 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) Ctf8 PF09696.10 KIY62404.1 - 2.3e-16 60.4 2.1 1.6e-13 51.2 2.1 2.9 1 1 0 1 1 1 1 Ctf8 FoP_duplication PF13865.6 KIY62406.1 - 0.00013 22.5 0.0 0.00014 22.3 0.0 1.1 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 RGS12_us1 PF16613.5 KIY62406.1 - 0.075 13.4 1.0 0.085 13.2 1.0 1.2 1 0 0 1 1 1 0 Unstructured region of RGS12 RRM_1 PF00076.22 KIY62407.1 - 4.5e-13 48.8 0.0 6.2e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KIY62407.1 - 0.064 13.1 0.0 0.079 12.8 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif RNA_pol_3_Rpc31 PF11705.8 KIY62408.1 - 6.6e-23 82.1 6.3 1.2e-22 81.3 6.3 1.4 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 IIGP PF05049.13 KIY62409.1 - 1.3e-27 96.8 0.7 2.1e-27 96.2 0.0 1.6 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) MMR_HSR1 PF01926.23 KIY62409.1 - 2.4e-07 30.8 1.6 7.3e-07 29.3 0.0 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIY62409.1 - 4.5e-06 26.7 0.5 0.00033 20.6 0.1 3.1 3 1 0 3 3 3 1 RsgA GTPase ABC_tran PF00005.27 KIY62409.1 - 0.00075 20.0 0.0 0.00075 20.0 0.0 2.6 2 1 0 2 2 1 1 ABC transporter Dynamin_N PF00350.23 KIY62409.1 - 0.0023 18.0 0.0 0.0023 18.0 0.0 3.3 2 1 1 3 3 3 1 Dynamin family Roc PF08477.13 KIY62409.1 - 0.0051 17.0 0.2 0.031 14.5 0.0 2.2 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 KIY62409.1 - 0.0094 15.7 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 KIY62409.1 - 0.016 15.0 0.1 0.063 13.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KIY62409.1 - 0.032 14.6 0.0 0.032 14.6 0.0 2.5 2 1 0 2 2 1 0 AAA ATPase domain DUF4407 PF14362.6 KIY62409.1 - 0.069 12.5 17.2 0.1 11.9 17.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AAA_7 PF12775.7 KIY62409.1 - 0.096 12.2 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region FeoB_N PF02421.18 KIY62409.1 - 0.2 11.2 0.0 0.35 10.4 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B Asp-B-Hydro_N PF05279.11 KIY62409.1 - 0.22 11.6 22.5 0.33 11.0 22.5 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region AAA_22 PF13401.6 KIY62409.1 - 0.26 11.6 0.1 0.26 11.6 0.1 2.3 1 1 1 2 2 2 0 AAA domain DUF4138 PF13595.6 KIY62409.1 - 0.4 9.9 4.3 0.15 11.3 0.2 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF4138) SMC_N PF02463.19 KIY62409.1 - 0.41 10.0 0.0 0.41 10.0 0.0 2.0 2 1 0 2 2 1 0 RecF/RecN/SMC N terminal domain DUF87 PF01935.17 KIY62409.1 - 0.53 10.3 0.0 0.53 10.3 0.0 2.6 2 1 0 2 2 1 0 Helicase HerA, central domain DUF3987 PF13148.6 KIY62409.1 - 0.8 8.6 0.0 0.8 8.6 0.0 3.2 1 1 2 3 3 2 0 Protein of unknown function (DUF3987) Exonuc_VII_L PF02601.15 KIY62409.1 - 5.2 6.6 17.7 7.3 6.1 17.7 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit UPF0242 PF06785.11 KIY62409.1 - 6.9 6.7 26.5 21 5.2 26.5 2.0 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus NPCC PF08058.11 KIY62410.1 - 0.28 11.3 6.5 5 7.2 0.8 2.4 2 0 0 2 2 2 0 Nuclear pore complex component DUF3328 PF11807.8 KIY62410.1 - 0.5 10.1 4.9 0.85 9.3 0.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF3328) Abhydrolase_9_N PF15420.6 KIY62410.1 - 0.92 9.5 12.2 0.44 10.5 1.5 2.3 1 1 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus adh_short PF00106.25 KIY62411.1 - 1.9e-06 27.5 0.0 3.9e-05 23.2 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KIY62411.1 - 0.015 15.3 0.0 0.022 14.7 0.0 1.2 1 0 0 1 1 1 0 KR domain TRP PF06011.12 KIY62413.1 - 0.00049 18.9 0.3 0.00049 18.9 0.3 1.7 2 0 0 2 2 2 1 Transient receptor potential (TRP) ion channel DUF3328 PF11807.8 KIY62413.1 - 0.0054 16.5 1.6 0.061 13.1 0.0 2.4 1 1 1 2 2 2 1 Domain of unknown function (DUF3328) DHHC PF01529.20 KIY62413.1 - 0.097 12.8 8.4 0.87 9.7 0.2 2.5 2 0 0 2 2 2 0 DHHC palmitoyltransferase CD34_antigen PF06365.12 KIY62413.1 - 0.17 11.4 0.3 0.32 10.5 0.1 1.6 1 1 0 1 1 1 0 CD34/Podocalyxin family HpcH_HpaI PF03328.14 KIY62414.1 - 1.4e-29 102.8 0.3 2e-29 102.3 0.3 1.2 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family adh_short PF00106.25 KIY62417.1 - 6e-10 38.9 0.0 1.7e-08 34.2 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KIY62417.1 - 2.8e-05 24.1 0.0 4.4e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 KIY62417.1 - 0.00016 21.3 0.0 0.00026 20.6 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Mt_ATP-synt_D PF05873.12 KIY62418.1 - 8.1 6.3 9.0 1 9.2 4.3 1.9 2 0 0 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) Brr6_like_C_C PF10104.9 KIY62421.1 - 4.9e-17 62.0 0.1 7.8e-17 61.3 0.1 1.2 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain DUF659 PF04937.15 KIY62423.1 - 0.032 14.1 0.0 0.035 13.9 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF 659) UL73_N PF12522.8 KIY62423.1 - 0.069 12.9 1.1 0.094 12.5 1.1 1.1 1 0 0 1 1 1 0 Cytomegalovirus glycoprotein N terminal DUF4413 PF14372.6 KIY62424.1 - 0.055 13.8 0.2 0.083 13.3 0.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4413) Dimer_Tnp_hAT PF05699.14 KIY62425.1 - 4.6e-23 80.8 0.0 5.8e-23 80.5 0.0 1.1 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region F-box-like PF12937.7 KIY62426.1 - 9.5e-09 35.0 0.7 3.8e-08 33.1 0.7 2.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY62426.1 - 0.035 14.0 4.3 4.2 7.4 0.4 3.3 3 0 0 3 3 3 0 F-box domain PLA2_B PF01735.18 KIY62427.1 - 4.4e-109 365.1 0.8 5.5e-109 364.8 0.8 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Exo_endo_phos PF03372.23 KIY62428.1 - 2.8e-13 49.9 0.0 9.2e-13 48.2 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Peptidase_M16_C PF05193.21 KIY62429.1 - 4.2e-16 59.5 0.0 2.5e-09 37.4 0.0 3.0 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KIY62429.1 - 3.9e-11 43.2 0.0 6.5e-09 35.9 0.0 2.4 2 0 0 2 2 2 2 Insulinase (Peptidase family M16) M16C_assoc PF08367.11 KIY62429.1 - 0.18 10.9 0.6 2.2 7.3 0.6 2.2 1 1 0 1 1 1 0 Peptidase M16C associated MgtE PF01769.16 KIY62430.1 - 1.6 9.1 5.8 0.41 11.0 0.2 2.2 2 1 0 2 2 2 0 Divalent cation transporter Nefa_Nip30_N PF10187.9 KIY62431.1 - 2.3e-27 95.4 6.3 2.3e-27 95.4 6.3 1.8 2 0 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 NUDE_C PF04880.13 KIY62432.1 - 2.3e-10 41.2 1.1 2.3e-10 41.2 1.1 4.9 2 2 3 5 5 2 1 NUDE protein, C-terminal conserved region TPR_MLP1_2 PF07926.12 KIY62432.1 - 0.025 14.7 27.4 1.1 9.3 2.2 4.1 2 1 2 4 4 4 0 TPR/MLP1/MLP2-like protein YiiD_C PF09500.10 KIY62432.1 - 0.081 12.8 0.4 0.44 10.4 0.0 2.3 2 0 0 2 2 2 0 Putative thioesterase (yiiD_Cterm) DUF4472 PF14739.6 KIY62432.1 - 0.11 13.3 13.9 0.075 13.8 3.2 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4472) PRKG1_interact PF15898.5 KIY62432.1 - 0.68 10.9 23.0 0.09 13.7 7.8 3.9 2 1 2 4 4 4 0 cGMP-dependent protein kinase interacting domain DUF4407 PF14362.6 KIY62432.1 - 0.97 8.7 16.5 0.39 10.0 8.6 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Laminin_II PF06009.12 KIY62432.1 - 1 9.4 10.2 5.1 7.1 1.2 3.6 3 2 1 4 4 4 0 Laminin Domain II DMPK_coil PF08826.10 KIY62432.1 - 1.1 9.4 9.5 0.53 10.4 0.5 3.4 2 1 1 3 3 3 0 DMPK coiled coil domain like Spc7 PF08317.11 KIY62432.1 - 1.4 7.7 22.8 0.2 10.5 8.2 2.6 2 1 1 3 3 3 0 Spc7 kinetochore protein DUF5082 PF16888.5 KIY62432.1 - 2.1 8.7 15.1 17 5.7 0.7 3.6 2 1 0 3 3 3 0 Domain of unknown function (DUF5082) Rab5-bind PF09311.11 KIY62432.1 - 3.5 6.9 19.5 21 4.4 19.6 2.1 1 1 0 1 1 1 0 Rabaptin-like protein DegS PF05384.11 KIY62432.1 - 3.8 7.0 13.2 0.29 10.6 5.7 2.4 1 1 1 2 2 2 0 Sensor protein DegS GAS PF13851.6 KIY62432.1 - 4.2 6.7 22.9 0.25 10.7 12.2 3.0 2 1 2 4 4 4 0 Growth-arrest specific micro-tubule binding ADIP PF11559.8 KIY62432.1 - 4.9 7.2 20.7 4.4 7.4 10.4 3.1 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding HIP1_clath_bdg PF16515.5 KIY62432.1 - 6 7.6 17.4 36 5.0 2.8 3.9 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 APG6_N PF17675.1 KIY62432.1 - 6.8 7.2 28.7 0.58 10.7 14.4 2.9 1 1 2 3 3 3 0 Apg6 coiled-coil region SlyX PF04102.12 KIY62432.1 - 8.1 7.1 14.2 2.8 8.6 1.6 4.3 3 1 1 4 4 4 0 SlyX TMF_TATA_bd PF12325.8 KIY62432.1 - 8.1 6.7 24.5 10 6.3 6.6 3.9 2 1 2 4 4 4 0 TATA element modulatory factor 1 TATA binding NUFIP1 PF10453.9 KIY62433.1 - 6.8e-17 61.1 0.2 1.1e-16 60.4 0.2 1.3 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) API5 PF05918.11 KIY62433.1 - 0.52 9.1 2.4 0.68 8.7 2.4 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Ipi1_N PF12333.8 KIY62434.1 - 1.4e-20 73.8 0.0 1.1e-19 70.9 0.0 2.6 2 0 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation LRR_6 PF13516.6 KIY62434.1 - 0.11 12.6 0.1 0.4 10.9 0.1 2.1 1 0 0 1 1 1 0 Leucine Rich repeat F-box-like PF12937.7 KIY62435.1 - 5e-08 32.7 1.6 1.3e-07 31.4 1.6 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY62435.1 - 0.12 12.3 1.3 2 8.4 1.3 2.7 1 1 0 1 1 1 0 F-box domain GPI-anchored PF10342.9 KIY62436.1 - 2.3e-09 37.9 1.1 4.1e-09 37.1 1.1 1.4 1 1 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Big_3_5 PF16640.5 KIY62436.1 - 0.03 14.5 1.1 0.041 14.1 1.1 1.2 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) DUF446 PF04287.12 KIY62438.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 tRNA pseudouridine synthase C Thaumatin PF00314.17 KIY62439.1 - 2.9e-14 53.2 5.2 6e-14 52.2 5.2 1.6 1 1 0 1 1 1 1 Thaumatin family Tyrosinase PF00264.20 KIY62440.1 - 3.2e-52 178.0 3.8 5.9e-52 177.2 3.8 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 KIY62440.1 - 4.5e-24 85.5 0.0 8e-24 84.6 0.0 1.4 1 0 0 1 1 1 1 Tyosinase C-terminal domain Ribosomal_L16 PF00252.18 KIY62442.1 - 6.8e-46 155.5 0.0 8.4e-46 155.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e U83 PF17465.2 KIY62442.1 - 0.049 13.8 0.0 0.08 13.1 0.0 1.3 1 0 0 1 1 1 0 Chemokine-like protein, HHV-6 U83 gene product BTB PF00651.31 KIY62443.1 - 1.1e-06 28.8 0.1 1.8e-06 28.2 0.1 1.3 1 0 0 1 1 1 1 BTB/POZ domain PITH PF06201.13 KIY62444.1 - 2.8e-35 121.8 0.8 3.3e-35 121.5 0.8 1.0 1 0 0 1 1 1 1 PITH domain F-box-like PF12937.7 KIY62445.1 - 6.8e-08 32.3 0.5 1.7e-07 31.0 0.5 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY62445.1 - 0.0013 18.5 1.1 0.047 13.6 1.1 2.8 1 1 0 1 1 1 1 F-box domain FlxA PF14282.6 KIY62445.1 - 0.002 18.1 0.1 0.0033 17.4 0.1 1.2 1 0 0 1 1 1 1 FlxA-like protein NPV_P10 PF05531.12 KIY62445.1 - 0.12 12.8 0.2 0.29 11.6 0.2 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein VIGSSK PF14773.6 KIY62446.1 - 0.41 10.8 2.3 2 8.6 0.2 2.2 2 0 0 2 2 2 0 Helicase-associated putative binding domain, C-terminal TT_ORF2 PF02957.15 KIY62446.1 - 5.3 8.0 5.8 1.7 9.5 3.0 1.6 2 0 0 2 2 2 0 TT viral ORF2 zf-C4H2 PF10146.9 KIY62447.1 - 0.13 12.6 2.3 0.2 11.9 2.3 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein UPF0047 PF01894.17 KIY62448.1 - 2.1e-37 127.8 0.2 2.4e-37 127.6 0.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 Fungal_trans PF04082.18 KIY62449.1 - 1.7e-08 33.9 0.0 2.8e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY62449.1 - 8.3e-07 29.0 12.1 1.9e-06 27.9 12.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box-like PF12937.7 KIY62450.1 - 0.00011 22.0 0.2 0.00051 19.9 0.0 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIY62450.1 - 0.00076 19.3 0.2 0.0037 17.1 0.2 2.3 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KIY62450.1 - 0.062 13.2 0.0 0.2 11.6 0.0 1.8 1 0 0 1 1 1 0 F-box KH_1 PF00013.29 KIY62451.1 - 1.4e-40 136.9 9.4 5e-15 55.1 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 KIY62451.1 - 3.3e-09 36.5 0.2 0.027 14.4 0.0 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KIY62451.1 - 1.6e-08 34.2 5.8 0.02 14.7 0.5 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 KIY62451.1 - 4.4e-05 23.5 3.9 0.093 12.8 0.0 3.4 3 0 0 3 3 3 2 NusA-like KH domain dUTPase PF00692.19 KIY62451.1 - 0.0011 18.6 0.3 0.11 12.1 0.0 2.5 2 0 0 2 2 2 1 dUTPase Ribosomal_L13 PF00572.18 KIY62452.1 - 1.8e-11 44.4 0.0 8.4e-10 39.0 0.0 2.3 1 1 0 1 1 1 1 Ribosomal protein L13 PP-binding PF00550.25 KIY62453.1 - 8.3e-14 51.7 0.3 1.2e-13 51.2 0.3 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 KIY62453.1 - 3.5e-07 30.3 0.5 4.9e-07 29.9 0.5 1.1 1 0 0 1 1 1 1 Acyl-carrier Ribosomal_L17 PF01196.19 KIY62454.1 - 3.7e-34 117.5 0.2 1.1e-33 116.0 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L17 DUF2192 PF09958.9 KIY62454.1 - 0.058 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2192) Tetraspanin PF00335.20 KIY62455.1 - 0.022 14.5 6.2 0.027 14.2 5.8 1.4 1 1 0 1 1 1 0 Tetraspanin family PRA1 PF03208.19 KIY62455.1 - 0.084 12.5 0.1 0.084 12.5 0.1 2.3 1 1 0 2 2 2 0 PRA1 family protein Phytase-like PF13449.6 KIY62456.1 - 7.8e-43 147.5 0.8 9.7e-43 147.1 0.8 1.1 1 0 0 1 1 1 1 Esterase-like activity of phytase SdiA-regulated PF06977.11 KIY62456.1 - 0.072 12.3 0.0 0.49 9.6 0.0 2.1 1 1 0 1 1 1 0 SdiA-regulated E1_DerP2_DerF2 PF02221.15 KIY62457.1 - 2.3e-24 86.4 0.5 2.8e-24 86.1 0.5 1.1 1 0 0 1 1 1 1 ML domain RhoGAP PF00620.27 KIY62458.1 - 9e-39 132.7 0.0 2.2e-38 131.4 0.0 1.6 2 0 0 2 2 2 1 RhoGAP domain COQ9 PF08511.11 KIY62460.1 - 1.2e-10 41.0 0.0 2.2e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 COQ9 eIF3_subunit PF08597.10 KIY62461.1 - 3.7e-65 220.2 18.6 4.1e-65 220.1 18.6 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit Pyr_redox_2 PF07992.14 KIY62463.1 - 1.3e-28 100.1 0.2 1.7e-28 99.7 0.2 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIY62463.1 - 1.3e-12 48.1 1.1 8.6e-11 42.2 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIY62463.1 - 0.00039 20.1 7.9 1.1 8.8 0.0 3.5 2 2 1 4 4 4 3 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KIY62463.1 - 0.00057 19.9 2.1 0.044 13.8 0.0 3.5 3 1 1 4 4 4 1 FAD-NAD(P)-binding TrkA_N PF02254.18 KIY62463.1 - 0.0016 18.7 0.0 0.084 13.1 0.0 2.5 2 1 0 2 2 2 1 TrkA-N domain Lycopene_cycl PF05834.12 KIY62463.1 - 0.0046 16.0 0.1 0.16 11.0 0.0 2.7 3 0 0 3 3 3 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KIY62463.1 - 0.0081 15.5 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Terminase_6 PF03237.15 KIY62463.1 - 0.026 14.2 0.0 0.051 13.2 0.0 1.5 1 0 0 1 1 1 0 Terminase-like family NAD_binding_7 PF13241.6 KIY62463.1 - 0.069 13.6 0.1 4.2 7.9 0.0 2.5 3 0 0 3 3 3 0 Putative NAD(P)-binding K_oxygenase PF13434.6 KIY62463.1 - 0.077 12.1 0.2 0.16 11.1 0.0 1.5 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Mur_ligase_C PF02875.21 KIY62463.1 - 0.18 12.1 0.0 0.42 10.9 0.0 1.6 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain Na_Ca_ex PF01699.24 KIY62464.1 - 6.3e-33 113.9 35.0 2.4e-16 60.0 14.8 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DnaJ_C PF01556.18 KIY62465.1 - 6.3e-38 130.2 0.0 9.1e-38 129.7 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KIY62465.1 - 2.8e-27 94.6 0.6 4.2e-27 94.0 0.6 1.3 1 0 0 1 1 1 1 DnaJ domain Pex26 PF07163.12 KIY62466.1 - 0.0035 16.7 0.0 0.0067 15.8 0.0 1.5 1 0 0 1 1 1 1 Pex26 protein Apt1 PF10351.9 KIY62466.1 - 0.18 10.6 2.5 0.23 10.3 2.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain NAM-associated PF14303.6 KIY62466.1 - 1.4 9.6 6.4 2.3 8.9 6.4 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain MAP65_ASE1 PF03999.12 KIY62466.1 - 1.5 7.4 11.0 2 7.0 11.0 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) RRM_1 PF00076.22 KIY62469.1 - 3.3e-13 49.2 0.0 8.9e-06 25.4 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KIY62469.1 - 0.014 15.5 0.0 0.15 12.2 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif VWA_2 PF13519.6 KIY62470.1 - 2e-24 86.3 0.8 5.2e-24 85.0 0.2 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 KIY62470.1 - 1.9e-09 38.0 0.8 2.8e-09 37.5 0.8 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain UIM PF02809.20 KIY62470.1 - 6.5e-09 35.1 25.1 0.0011 18.7 2.8 3.8 3 1 0 3 3 3 3 Ubiquitin interaction motif Ssl1 PF04056.14 KIY62470.1 - 2.3e-05 24.3 0.0 3.7e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Ssl1-like RAP80_UIM PF18282.1 KIY62470.1 - 0.016 14.9 7.3 2.3 8.1 4.1 3.1 2 1 0 2 2 2 0 RAP80 N-terminal ubiquitin interaction motif adh_short PF00106.25 KIY62471.1 - 5.2e-09 35.8 0.0 0.00019 20.9 0.0 3.1 3 1 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 KIY62471.1 - 0.00016 21.3 0.0 0.12 11.9 0.0 2.4 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Acetyltransf_CG PF14542.6 KIY62471.1 - 0.0046 17.1 0.1 0.016 15.4 0.0 1.9 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase Actino_peptide PF14408.6 KIY62471.1 - 0.12 12.5 0.0 0.69 10.1 0.0 2.2 2 0 0 2 2 2 0 Ribosomally synthesised peptide in actinomycetes SAM_Exu PF18609.1 KIY62472.1 - 0.048 13.7 0.1 0.15 12.2 0.1 1.8 2 0 0 2 2 2 0 Exuperantia SAM-like domain Pkinase PF00069.25 KIY62472.1 - 0.075 12.4 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain Glyco_transf_24 PF18404.1 KIY62473.1 - 0.00063 19.2 0.3 0.0058 16.1 0.1 2.3 1 1 2 3 3 3 1 Glucosyltransferase 24 Glyco_transf_8 PF01501.20 KIY62473.1 - 0.074 12.6 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 8 DUF616 PF04765.13 KIY62473.1 - 0.15 11.3 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF616) CAS_CSE1 PF03378.15 KIY62475.1 - 3e-120 401.7 1.4 2.4e-118 395.5 0.7 2.1 2 0 0 2 2 2 2 CAS/CSE protein, C-terminus Cse1 PF08506.10 KIY62475.1 - 1.9e-101 339.5 0.0 3.2e-101 338.8 0.0 1.4 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.19 KIY62475.1 - 2.7e-11 43.2 0.4 1.6e-10 40.8 0.1 2.6 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.12 KIY62475.1 - 0.0092 16.1 2.5 0.076 13.1 0.0 3.5 4 0 0 4 4 4 1 Exportin 1-like protein DUF2830 PF11125.8 KIY62475.1 - 0.028 14.4 0.5 10 6.2 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2830) DNA_pol_phi PF04931.13 KIY62475.1 - 0.11 10.5 0.2 0.34 9.0 0.0 1.8 2 0 0 2 2 2 0 DNA polymerase phi HEAT_2 PF13646.6 KIY62475.1 - 0.17 12.3 7.5 2.1 8.8 0.3 3.9 3 1 1 4 4 4 0 HEAT repeats SapB_2 PF03489.17 KIY62475.1 - 0.65 10.2 1.7 1.5 9.0 0.2 2.6 3 0 0 3 3 3 0 Saposin-like type B, region 2 adh_short_C2 PF13561.6 KIY62476.1 - 1.4e-48 165.5 1.9 1.8e-48 165.2 1.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIY62476.1 - 6.1e-35 120.5 0.6 8.5e-35 120.0 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIY62476.1 - 3.9e-12 46.5 1.1 5.6e-12 45.9 1.1 1.1 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 KIY62476.1 - 0.0018 18.5 0.1 0.0036 17.6 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain His_biosynth PF00977.21 KIY62476.1 - 0.0059 16.1 0.2 0.011 15.2 0.1 1.5 2 0 0 2 2 2 1 Histidine biosynthesis protein zf-CCCH_3 PF15663.5 KIY62480.1 - 0.013 15.7 0.0 0.035 14.3 0.0 1.7 1 0 0 1 1 1 0 Zinc-finger containing family zf-CCCH_2 PF14608.6 KIY62480.1 - 1.1 9.8 9.4 3.1 8.4 9.4 1.8 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger DUF1932 PF09130.11 KIY62481.1 - 1.3e-11 44.3 0.0 4.2e-11 42.7 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1932) NAD_binding_2 PF03446.15 KIY62481.1 - 7.4e-08 32.7 0.0 1.6e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KIY62481.1 - 1.4e-05 25.6 0.4 3.1e-05 24.5 0.4 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.12 KIY62481.1 - 0.00049 19.7 0.2 0.00093 18.8 0.2 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain ApbA PF02558.16 KIY62481.1 - 0.043 13.5 0.9 0.091 12.4 0.9 1.7 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA RRP36 PF06102.12 KIY62481.1 - 0.043 13.8 0.0 0.071 13.1 0.0 1.3 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 DUF1932 PF09130.11 KIY62482.1 - 1.2e-09 38.0 0.4 3.3e-09 36.6 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1932) F420_oxidored PF03807.17 KIY62482.1 - 2.5e-06 28.0 1.7 3.9e-06 27.4 0.1 2.1 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 KIY62482.1 - 0.00024 21.3 0.0 0.00053 20.2 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 KIY62482.1 - 0.00078 19.1 0.0 0.0017 18.0 0.0 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Shikimate_DH PF01488.20 KIY62482.1 - 0.026 14.6 0.1 0.08 13.0 0.0 1.9 2 1 1 3 3 3 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 KIY62482.1 - 0.052 13.2 0.1 0.1 12.3 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 KIY62482.1 - 0.076 12.9 0.1 0.18 11.6 0.1 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GAD-like PF08887.11 KIY62483.1 - 0.007 16.1 0.0 0.017 14.9 0.0 1.6 1 0 0 1 1 1 1 GAD-like domain Trypsin_2 PF13365.6 KIY62483.1 - 0.1 13.5 0.0 11 6.9 0.0 2.6 2 0 0 2 2 2 0 Trypsin-like peptidase domain HTH_48 PF17906.1 KIY62483.1 - 0.12 12.5 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 HTH domain in Mos1 transposase Peptidase_S32 PF05579.13 KIY62483.1 - 0.19 10.9 0.0 0.32 10.2 0.0 1.3 1 0 0 1 1 1 0 Equine arteritis virus serine endopeptidase S32 WD40 PF00400.32 KIY62484.1 - 7.5e-06 26.6 0.5 0.014 16.2 0.1 3.0 2 0 0 2 2 2 2 WD domain, G-beta repeat Cytochrom_D1 PF02239.16 KIY62484.1 - 4.1e-05 22.3 0.0 0.00017 20.2 0.0 2.0 3 0 0 3 3 3 1 Cytochrome D1 heme domain PD40 PF07676.12 KIY62484.1 - 0.00038 20.3 0.1 0.042 13.8 0.0 2.9 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat ANAPC4_WD40 PF12894.7 KIY62484.1 - 0.0019 18.4 0.0 1.7 9.0 0.0 2.7 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIY62484.1 - 0.059 12.3 0.1 0.81 8.6 0.0 2.4 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein HMG_box_5 PF14887.6 KIY62484.1 - 0.26 11.3 0.8 0.62 10.1 0.8 1.6 1 0 0 1 1 1 0 HMG (high mobility group) box 5 EAP30 PF04157.16 KIY62485.1 - 0.016 14.5 0.1 0.019 14.2 0.1 1.1 1 0 0 1 1 1 0 EAP30/Vps36 family CMAS PF02353.20 KIY62486.1 - 4e-33 114.9 0.0 5.9e-33 114.3 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 KIY62486.1 - 2.6e-13 50.5 0.0 4.9e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIY62486.1 - 8.5e-12 45.6 0.0 1.5e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIY62486.1 - 1.4e-11 44.4 0.0 3e-11 43.4 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIY62486.1 - 1.7e-08 34.5 0.0 3.3e-08 33.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIY62486.1 - 1.9e-08 34.9 0.0 3.4e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KIY62486.1 - 1.4e-06 27.9 0.0 2.9e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 KIY62486.1 - 1.6e-05 24.5 0.0 2.7e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain TehB PF03848.14 KIY62486.1 - 0.00011 21.6 0.0 0.00021 20.7 0.0 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltr_RsmB-F PF01189.17 KIY62486.1 - 0.0026 17.4 0.0 0.0047 16.6 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F GidB PF02527.15 KIY62486.1 - 0.0042 16.4 0.0 0.0077 15.6 0.0 1.4 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G PCMT PF01135.19 KIY62486.1 - 0.036 13.8 0.0 0.06 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) NodS PF05401.11 KIY62486.1 - 0.044 13.4 0.0 0.09 12.4 0.0 1.5 1 0 0 1 1 1 0 Nodulation protein S (NodS) DOT1 PF08123.13 KIY62486.1 - 0.049 13.1 0.0 0.086 12.4 0.0 1.4 1 0 0 1 1 1 0 Histone methylation protein DOT1 Ubie_methyltran PF01209.18 KIY62486.1 - 0.093 12.0 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 KIY62486.1 - 0.14 11.4 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_32 PF13679.6 KIY62486.1 - 0.15 12.0 0.1 0.72 9.8 0.0 1.9 1 1 1 2 2 2 0 Methyltransferase domain MetW PF07021.12 KIY62486.1 - 0.18 11.3 0.0 0.39 10.3 0.0 1.5 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW MDM31_MDM32 PF08118.11 KIY62487.1 - 1.7e-195 650.7 0.0 2e-195 650.5 0.0 1.0 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins ABC_membrane_2 PF06472.15 KIY62487.1 - 0.1 12.0 2.5 1.6 8.1 0.0 2.4 2 0 0 2 2 2 0 ABC transporter transmembrane region 2 MFS_1 PF07690.16 KIY62488.1 - 9.4e-34 116.9 59.3 1.6e-32 112.8 56.0 3.5 1 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KIY62488.1 - 5.6e-18 64.7 13.3 8.7e-18 64.1 13.3 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KIY62488.1 - 3e-11 42.8 14.5 3e-11 42.8 14.5 2.5 3 0 0 3 3 3 2 Sugar (and other) transporter HalOD1 PF18545.1 KIY62488.1 - 0.11 12.8 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Halobacterial output domain 1 Pkinase PF00069.25 KIY62489.1 - 9.1e-64 215.4 0.0 1.2e-63 215.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY62489.1 - 2.4e-32 112.2 0.0 3.5e-32 111.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KIY62489.1 - 0.0033 16.8 0.1 0.0065 15.8 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIY62489.1 - 0.023 14.6 0.3 0.11 12.3 0.0 2.2 3 0 0 3 3 3 0 Phosphotransferase enzyme family Acetyltransf_4 PF13420.7 KIY62491.1 - 1.2e-24 87.3 0.0 1.3e-24 87.1 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KIY62491.1 - 1.5e-10 41.9 0.0 1.8e-10 41.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIY62491.1 - 1.7e-08 34.7 0.1 2.1e-08 34.4 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KIY62491.1 - 1.1e-06 28.6 0.0 1.4e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KIY62491.1 - 5.4e-06 26.8 0.1 9.1e-06 26.0 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIY62491.1 - 0.0044 17.0 0.0 0.0079 16.1 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 KIY62491.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Bac_rhamnosid6H PF17389.2 KIY62492.1 - 1.3e-17 64.1 0.0 1.9e-17 63.6 0.0 1.2 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_C PF17390.2 KIY62492.1 - 4.9e-05 23.0 0.0 0.00018 21.2 0.0 1.9 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase C-terminal domain Trehalase PF01204.18 KIY62492.1 - 0.00017 20.6 0.2 0.00027 19.9 0.2 1.2 1 0 0 1 1 1 1 Trehalase DUF4019 PF13211.6 KIY62492.1 - 0.0032 17.8 0.2 0.0066 16.8 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4019) BLF1 PF17752.1 KIY62492.1 - 0.031 13.6 3.6 0.019 14.3 1.1 1.9 2 0 0 2 2 2 0 Burkholderia lethal factor 1 GDE_C PF06202.14 KIY62492.1 - 0.053 12.5 0.1 0.11 11.4 0.0 1.4 1 1 0 1 1 1 0 Amylo-alpha-1,6-glucosidase SNF2_N PF00176.23 KIY62493.1 - 1.2e-53 182.1 0.0 3e-53 180.8 0.0 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KIY62493.1 - 2.4e-14 53.6 0.0 4.7e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIY62493.1 - 6.8e-10 39.2 0.0 1.6e-09 38.0 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KIY62493.1 - 1e-06 28.6 0.0 2.2e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2439 PF10382.9 KIY62493.1 - 0.00037 20.8 0.1 0.12 12.7 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF2439) HDA2-3 PF11496.8 KIY62493.1 - 0.024 13.8 1.0 0.035 13.3 0.0 1.7 2 0 0 2 2 2 0 Class II histone deacetylase complex subunits 2 and 3 Mst1_SARAH PF11629.8 KIY62493.1 - 0.058 13.5 0.1 0.17 12.0 0.1 1.8 1 0 0 1 1 1 0 C terminal SARAH domain of Mst1 F-box-like PF12937.7 KIY62494.1 - 0.0018 18.2 0.1 0.0088 15.9 0.0 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIY62494.1 - 0.0038 17.1 0.1 0.012 15.5 0.1 1.9 1 0 0 1 1 1 1 F-box domain JmjC PF02373.22 KIY62495.1 - 8.8e-37 126.0 0.1 1.5e-36 125.3 0.1 1.4 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.17 KIY62495.1 - 2.3e-14 53.0 0.2 5e-14 52.0 0.2 1.6 1 0 0 1 1 1 1 jmjN domain zf-HC5HC2H PF13771.6 KIY62495.1 - 2.4e-12 47.0 0.8 4.6e-12 46.0 0.8 1.5 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 KIY62495.1 - 1.4e-09 38.1 0.5 2.9e-09 37.1 0.5 1.5 1 0 0 1 1 1 1 PHD-zinc-finger like domain Rdx PF10262.9 KIY62495.1 - 0.02 15.1 0.0 0.053 13.7 0.0 1.6 1 0 0 1 1 1 0 Rdx family PHD PF00628.29 KIY62495.1 - 1.1 9.2 5.7 0.37 10.7 1.0 2.3 2 0 0 2 2 2 0 PHD-finger Fungus-induced PF10917.8 KIY62496.1 - 1.9 8.9 6.1 3.4 8.1 6.1 1.6 1 1 0 1 1 1 0 Fungus-induced protein Phage_holin_1 PF04531.13 KIY62499.1 - 7.4 7.2 7.6 1.6 9.3 2.0 2.6 2 1 1 3 3 3 0 Bacteriophage holin p450 PF00067.22 KIY62500.1 - 1.9e-21 76.3 0.0 1e-11 44.3 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Phage_integrase PF00589.22 KIY62501.1 - 2.1e-05 24.4 0.0 3.6e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Phage integrase family Cytochrom_C1 PF02167.15 KIY62505.1 - 0.003 17.3 0.1 0.0053 16.5 0.1 1.3 1 0 0 1 1 1 1 Cytochrome C1 family Tctex-1 PF03645.13 KIY62507.1 - 0.035 14.3 0.1 0.059 13.6 0.1 1.4 1 0 0 1 1 1 0 Tctex-1 family KDZ PF18758.1 KIY62508.1 - 2.3e-39 135.3 0.1 3.7e-39 134.7 0.1 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KIY62508.1 - 1.3e-23 83.2 0.0 3.3e-23 81.9 0.0 1.7 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KIY62508.1 - 0.014 15.5 0.0 0.034 14.3 0.0 1.6 1 0 0 1 1 1 0 CxC1 like cysteine cluster associated with KDZ transposases zf-UBR PF02207.20 KIY62508.1 - 0.43 10.8 5.8 0.072 13.3 0.7 2.4 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) Rpp20 PF12328.8 KIY62509.1 - 1.3e-09 38.2 0.0 5.7e-07 29.6 0.0 2.1 1 1 1 2 2 2 2 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.21 KIY62509.1 - 0.00091 19.0 0.0 0.0016 18.2 0.0 1.4 1 0 0 1 1 1 1 Alba eRF1_2 PF03464.15 KIY62510.1 - 2e-47 160.8 0.1 3.5e-47 160.0 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 KIY62510.1 - 2.5e-39 134.2 0.5 5.9e-39 133.1 0.5 1.7 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 KIY62510.1 - 6.1e-19 68.3 0.0 1.1e-18 67.5 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 acVLRF1 PF18859.1 KIY62510.1 - 1.9e-11 44.4 0.3 3e-11 43.7 0.3 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor baeRF_family10 PF18854.1 KIY62510.1 - 6.2e-09 36.2 0.1 1.1e-08 35.4 0.1 1.4 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 Ribosomal_L7Ae PF01248.26 KIY62510.1 - 0.085 12.6 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF1540 PF07561.11 KIY62511.1 - 0.015 15.6 0.2 9.4 6.6 0.0 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1540) Peptidase_M50B PF13398.6 KIY62513.1 - 1.2e-55 188.3 24.6 1.7e-55 187.8 24.6 1.2 1 0 0 1 1 1 1 Peptidase M50B-like DUF92 PF01940.16 KIY62513.1 - 0.059 12.8 12.7 1.5 8.2 6.4 2.7 2 1 0 2 2 2 0 Integral membrane protein DUF92 rhaM PF05336.13 KIY62514.1 - 2.5e-33 114.4 0.0 2.8e-33 114.2 0.0 1.0 1 0 0 1 1 1 1 L-rhamnose mutarotase DUF4964 PF16334.5 KIY62514.1 - 0.092 12.3 0.1 0.14 11.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4964) Ras PF00071.22 KIY62515.1 - 6.5e-62 207.9 0.2 7.7e-62 207.7 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIY62515.1 - 9.9e-35 119.4 0.1 1.4e-34 118.8 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIY62515.1 - 9.3e-12 44.7 0.1 1.2e-11 44.4 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KIY62515.1 - 4e-07 30.1 0.1 6.5e-07 29.4 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIY62515.1 - 0.00014 21.9 0.1 0.018 15.0 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 KIY62515.1 - 0.00014 21.4 0.2 0.00049 19.7 0.2 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 KIY62515.1 - 0.0031 17.8 0.0 0.041 14.2 0.0 2.3 2 1 0 2 2 1 1 AAA domain SRPRB PF09439.10 KIY62515.1 - 0.0093 15.4 0.0 0.021 14.3 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 KIY62515.1 - 0.015 15.1 0.0 0.052 13.3 0.0 1.8 1 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.12 KIY62515.1 - 0.018 14.4 0.0 0.026 13.9 0.0 1.3 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 KIY62515.1 - 0.02 14.5 0.2 0.074 12.6 0.2 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_16 PF13191.6 KIY62515.1 - 0.02 15.3 0.1 0.031 14.7 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 KIY62515.1 - 0.035 14.6 0.1 0.055 14.0 0.1 1.4 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 KIY62515.1 - 0.04 13.6 0.0 0.085 12.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 KIY62515.1 - 0.098 12.0 0.0 0.25 10.7 0.0 1.6 2 0 0 2 2 2 0 Bacterial TniB protein MCM PF00493.23 KIY62515.1 - 0.099 11.7 0.0 0.2 10.7 0.0 1.5 2 0 0 2 2 2 0 MCM P-loop domain YvfG PF09628.10 KIY62515.1 - 0.15 12.5 0.1 0.3 11.5 0.1 1.5 1 0 0 1 1 1 0 YvfG protein AAA_7 PF12775.7 KIY62515.1 - 0.16 11.5 0.0 0.34 10.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 KIY62515.1 - 0.16 12.0 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_21 PF13304.6 KIY62515.1 - 0.18 11.6 0.6 0.29 10.9 0.6 1.4 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF4404 PF14357.6 KIY62517.1 - 7.4 7.3 7.2 3.7 8.3 2.9 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) GAGA_bind PF06217.12 KIY62518.1 - 0.67 10.2 5.2 0.1 12.8 0.2 1.9 2 0 0 2 2 2 0 GAGA binding protein-like family ubiquitin PF00240.23 KIY62522.1 - 1.6e-08 34.1 0.4 0.0045 16.7 0.1 2.1 2 0 0 2 2 2 2 Ubiquitin family Ribosomal_L40e PF01020.17 KIY62523.1 - 1.8e-09 37.3 2.9 2.7e-09 36.8 2.9 1.3 1 0 0 1 1 1 1 Ribosomal L40e family ubiquitin PF00240.23 KIY62523.1 - 0.0027 17.4 0.1 0.0044 16.8 0.1 1.5 1 1 0 1 1 1 1 Ubiquitin family CCDC92 PF14916.6 KIY62524.1 - 0.0099 15.6 0.6 0.017 14.8 0.6 1.4 1 0 0 1 1 1 1 Coiled-coil domain of unknown function DASH_Spc19 PF08287.11 KIY62524.1 - 0.013 15.4 1.5 0.013 15.4 1.5 1.5 1 1 1 2 2 2 0 Spc19 CC2-LZ PF16516.5 KIY62524.1 - 0.02 15.3 1.5 0.032 14.6 1.5 1.3 1 0 0 1 1 1 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator CASP_C PF08172.12 KIY62524.1 - 1.1 8.5 4.2 1.8 7.9 3.0 1.7 1 1 1 2 2 2 0 CASP C terminal GAS PF13851.6 KIY62525.1 - 1.1e-05 24.9 27.0 1.1e-05 24.9 27.0 3.3 2 1 1 3 3 3 1 Growth-arrest specific micro-tubule binding Tropomyosin PF00261.20 KIY62525.1 - 0.0051 16.2 1.3 0.0051 16.2 1.3 4.8 1 1 3 5 5 5 2 Tropomyosin Tropomyosin_1 PF12718.7 KIY62525.1 - 0.0081 16.3 18.1 0.0081 16.3 18.1 4.4 2 1 2 4 4 4 2 Tropomyosin like DUF4250 PF14056.6 KIY62525.1 - 3.6 7.6 10.7 3.1 7.8 0.4 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4250) ATG16 PF08614.11 KIY62525.1 - 5.5 7.2 61.0 0.24 11.6 27.8 3.8 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Peptidase_S28 PF05577.12 KIY62526.1 - 1.2e-52 179.2 0.0 5.4e-52 177.0 0.0 1.8 1 1 0 1 1 1 1 Serine carboxypeptidase S28 STE3 PF02076.15 KIY62528.1 - 2.1e-88 296.3 14.0 2.6e-88 296.0 14.0 1.1 1 0 0 1 1 1 1 Pheromone A receptor Acetyltransf_3 PF13302.7 KIY62529.1 - 6.6e-20 72.2 0.0 8.6e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIY62529.1 - 2e-08 34.5 0.0 3.1e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 KIY62529.1 - 2.8e-05 23.8 0.0 4e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIY62529.1 - 0.011 15.6 0.0 0.018 15.0 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein DUF2824 PF11039.8 KIY62529.1 - 0.13 12.2 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2824) DNApol_Exo PF18136.1 KIY62530.1 - 6.7e-96 320.7 0.0 2.2e-95 319.1 0.0 1.9 1 1 0 1 1 1 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 KIY62530.1 - 2.8e-46 158.3 0.0 4.9e-46 157.5 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.20 KIY62530.1 - 0.11 12.2 0.0 1.6 8.4 0.0 2.2 2 0 0 2 2 2 0 3'-5' exonuclease zf-C2H2_jaz PF12171.8 KIY62531.1 - 2.5e-07 30.8 3.9 0.0013 19.0 0.0 2.6 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KIY62531.1 - 0.005 17.6 6.7 0.056 14.3 0.1 3.7 3 1 0 3 3 3 1 C2H2-type zinc finger zf-met PF12874.7 KIY62531.1 - 0.0096 16.3 5.5 0.13 12.7 0.1 3.1 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 KIY62531.1 - 0.012 16.0 0.1 0.012 16.0 0.1 3.0 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 KIY62531.1 - 0.028 14.8 2.3 2.3 8.6 0.0 2.8 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zinc_ribbon_9 PF14369.6 KIY62531.1 - 0.59 10.4 3.6 1.9 8.8 0.9 2.7 2 1 1 3 3 3 0 zinc-ribbon FAD_oxidored PF12831.7 KIY62532.1 - 0.00066 19.1 0.0 0.00093 18.6 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase UPF0227 PF05728.12 KIY62532.1 - 0.083 12.8 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) InaF-motif PF15018.6 KIY62532.1 - 0.087 12.7 1.5 0.16 11.8 1.5 1.4 1 0 0 1 1 1 0 TRP-interacting helix Trp_halogenase PF04820.14 KIY62532.1 - 0.15 10.9 0.0 7.4 5.3 0.0 2.7 3 0 0 3 3 3 0 Tryptophan halogenase FAD_oxidored PF12831.7 KIY62533.1 - 0.00049 19.6 0.0 0.0012 18.3 0.0 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KIY62533.1 - 0.0015 17.5 0.0 1.2 7.8 0.0 2.6 3 0 0 3 3 3 2 Tryptophan halogenase UPF0227 PF05728.12 KIY62533.1 - 0.028 14.4 0.0 0.14 12.0 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) DUF5422 PF17459.2 KIY62534.1 - 1.6 8.9 8.3 0.21 11.8 1.4 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5422) GATA PF00320.27 KIY62535.1 - 2.2e-25 88.0 20.8 1.1e-14 53.8 4.3 2.5 2 0 0 2 2 2 2 GATA zinc finger DUF1752 PF08550.10 KIY62535.1 - 0.0016 18.3 0.0 0.0041 16.9 0.0 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) DZR PF12773.7 KIY62535.1 - 0.65 10.1 10.0 6.5 6.9 0.9 3.1 2 1 1 3 3 3 0 Double zinc ribbon eIF-5_eIF-2B PF01873.17 KIY62535.1 - 1.4 8.8 5.9 3.1 7.7 0.4 2.3 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Auto_anti-p27 PF06677.12 KIY62535.1 - 1.7 8.8 5.4 8.8 6.6 0.5 2.5 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Cytochrome_C7 PF14522.6 KIY62535.1 - 1.9 8.6 5.5 0.94 9.5 2.8 1.9 1 1 1 2 2 2 0 Cytochrome c7 and related cytochrome c CTP_transf_like PF01467.26 KIY62537.1 - 3.4e-06 27.3 0.0 4.9e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase-like FAD_syn PF06574.12 KIY62537.1 - 0.062 13.2 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 FAD synthetase Lactonase PF10282.9 KIY62538.1 - 1e-49 169.6 0.0 1.2e-49 169.5 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller ArAE_2 PF10334.9 KIY62539.1 - 2e-51 175.0 0.0 3.1e-51 174.4 0.0 1.3 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 ArAE_2_N PF10337.9 KIY62539.1 - 8.2e-37 127.3 6.4 8.4e-36 124.0 6.4 2.3 1 1 0 1 1 1 1 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 KIY62539.1 - 2.2e-12 47.2 9.3 2.2e-12 47.2 9.3 3.2 2 1 0 2 2 2 1 Fusaric acid resistance protein-like VEGFR-2_TMD PF17988.1 KIY62539.1 - 7.8 6.0 9.6 2.7 7.5 0.2 3.5 3 0 0 3 3 3 0 VEGFR-2 Transmembrane domain DUF1752 PF08550.10 KIY62540.1 - 3.6e-11 42.7 0.5 6.1e-11 41.9 0.5 1.4 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) MFS_1 PF07690.16 KIY62541.1 - 4.3e-44 150.9 37.5 4.7e-44 150.8 31.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIY62541.1 - 1.7e-16 60.1 2.9 1.7e-16 60.1 2.9 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KIY62541.1 - 2.1e-07 29.8 0.5 4.7e-07 28.6 0.5 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 KIY62541.1 - 5.7e-07 29.2 0.8 5.7e-07 29.2 0.8 2.6 2 1 1 3 3 3 1 Uncharacterised MFS-type transporter YbfB AA_permease_2 PF13520.6 KIY62542.1 - 2.6e-08 33.1 2.6 2.8e-08 33.0 2.6 1.0 1 0 0 1 1 1 1 Amino acid permease BA14K PF07886.11 KIY62545.1 - 0.15 12.0 0.1 0.29 11.1 0.1 1.5 1 0 0 1 1 1 0 BA14K-like protein RNA_pol_Rpa2_4 PF06883.12 KIY62545.1 - 0.16 12.0 0.0 0.33 11.0 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase I, Rpa2 specific domain AT_hook PF02178.19 KIY62546.1 - 0.039 13.8 0.2 0.096 12.6 0.2 1.7 1 0 0 1 1 1 0 AT hook motif DUF936 PF06075.12 KIY62547.1 - 9.3 5.0 14.0 1.5 7.6 7.0 2.1 2 0 0 2 2 2 0 Plant protein of unknown function (DUF936) KDZ PF18758.1 KIY62549.1 - 3.2e-53 180.6 1.5 8.7e-53 179.2 1.0 2.0 2 0 0 2 2 2 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KIY62549.1 - 1.3e-28 99.3 0.0 8.1e-28 96.7 0.0 2.2 2 0 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KIY62549.1 - 1.6e-05 25.0 0.0 6.4e-05 23.0 0.0 2.0 2 0 0 2 2 2 1 CxC1 like cysteine cluster associated with KDZ transposases Ipi1_N PF12333.8 KIY62550.1 - 0.25 11.9 0.6 1.8 9.2 0.0 2.3 2 0 0 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation Phage_holin_5_2 PF16079.5 KIY62551.1 - 0.018 15.4 2.9 2.2 8.7 0.0 2.4 1 1 1 2 2 2 0 Phage holin family Hol44, in holin superfamily V FtsL PF04999.13 KIY62551.1 - 0.85 9.7 4.0 10 6.2 0.2 2.4 2 1 0 2 2 2 0 Cell division protein FtsL CytB6-F_Fe-S PF08802.10 KIY62552.1 - 1.7 8.7 3.8 2.7 8.1 3.8 1.3 1 0 0 1 1 1 0 Cytochrome B6-F complex Fe-S subunit FCH PF00611.23 KIY62553.1 - 7.9e-14 51.7 0.1 6e-13 48.9 0.0 2.3 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 KIY62553.1 - 1.1e-10 40.9 0.0 8e-10 38.2 0.2 2.2 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KIY62553.1 - 4.2e-08 32.9 0.0 1.3e-07 31.3 0.1 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 KIY62553.1 - 9.4e-06 25.2 0.0 7e-05 22.4 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain N2227 PF07942.12 KIY62554.1 - 5.1e-70 235.8 0.0 6.4e-70 235.4 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.6 KIY62554.1 - 2e-09 37.5 0.0 4.1e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIY62554.1 - 2.1e-05 25.2 0.0 0.00031 21.4 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIY62554.1 - 0.00053 20.6 0.1 0.21 12.3 0.0 3.2 2 1 0 2 2 2 1 Methyltransferase domain Aminopep PF10023.9 KIY62554.1 - 0.1 12.0 1.2 0.15 11.4 0.5 1.5 2 0 0 2 2 2 0 Putative aminopeptidase Methyltransf_25 PF13649.6 KIY62554.1 - 0.12 13.1 0.1 16 6.3 0.0 3.0 2 1 0 2 2 2 0 Methyltransferase domain zf-H2C2_2 PF13465.6 KIY62556.1 - 4.3e-08 33.2 1.8 6.3e-05 23.2 0.0 3.4 4 0 0 4 4 4 2 Zinc-finger double domain FOXP-CC PF16159.5 KIY62556.1 - 6.1e-08 33.2 4.6 9.8e-05 22.9 1.1 2.9 2 1 1 3 3 3 2 FOXP coiled-coil domain zf-C2H2 PF00096.26 KIY62556.1 - 1.7e-06 28.1 5.1 0.015 15.7 0.0 3.7 3 1 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIY62556.1 - 0.00016 22.3 5.4 0.05 14.4 0.0 3.5 3 1 0 3 3 3 2 C2H2-type zinc finger zf-Di19 PF05605.12 KIY62556.1 - 0.0019 18.5 1.4 1 9.7 0.1 2.4 1 1 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf_ZIC PF18366.1 KIY62556.1 - 0.015 15.4 1.7 0.17 12.0 0.2 3.0 3 1 0 3 3 3 0 Zic proteins zinc finger domain zf-C2H2_6 PF13912.6 KIY62556.1 - 0.064 13.3 0.2 1.1 9.4 0.0 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger Pox_Ag35 PF03286.14 KIY62560.1 - 0.085 12.6 9.7 0.11 12.3 9.7 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Zip PF02535.22 KIY62560.1 - 0.7 9.1 4.7 0.79 8.9 4.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter BUD22 PF09073.10 KIY62560.1 - 1.1 8.5 14.8 1.1 8.5 14.8 1.1 1 0 0 1 1 1 0 BUD22 SURF2 PF05477.11 KIY62560.1 - 1.7 8.2 9.1 1.9 8.1 9.1 1.1 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) NPR3 PF03666.13 KIY62560.1 - 3.9 6.2 5.3 4.3 6.0 5.3 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Nop14 PF04147.12 KIY62560.1 - 4.6 5.3 20.2 5 5.2 20.2 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 KIY62560.1 - 4.8 6.5 22.1 5.3 6.4 22.1 1.0 1 0 0 1 1 1 0 SDA1 Cwf_Cwc_15 PF04889.12 KIY62560.1 - 5.5 6.6 17.7 7.7 6.2 17.7 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Phage_holin_5_2 PF16079.5 KIY62561.1 - 0.059 13.7 1.3 8.1 6.9 0.0 2.6 2 0 0 2 2 2 0 Phage holin family Hol44, in holin superfamily V GTP_EFTU PF00009.27 KIY62562.1 - 2.2e-65 219.8 0.2 2.6e-65 219.6 0.2 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KIY62562.1 - 2.2e-05 24.7 0.1 6.9e-05 23.2 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KIY62562.1 - 5.7e-05 23.2 0.1 0.00014 21.9 0.1 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 KIY62562.1 - 0.096 12.4 0.2 0.72 9.6 0.1 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ICL PF00463.21 KIY62563.1 - 5.6e-188 625.7 0.0 6.5e-188 625.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 KIY62563.1 - 4.4e-09 36.2 0.1 1.1e-08 34.9 0.0 1.6 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase APH PF01636.23 KIY62564.1 - 3.8e-13 49.9 0.1 6.7e-13 49.1 0.1 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 KIY62564.1 - 1.4e-08 34.1 0.0 1.9e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) EcKinase PF02958.20 KIY62564.1 - 3.1e-07 30.0 0.0 5e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.20 KIY62564.1 - 0.00025 20.7 0.0 0.00042 20.0 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase pPIWI_RE_X PF13111.6 KIY62564.1 - 0.014 14.6 0.1 0.033 13.4 0.0 1.6 2 0 0 2 2 2 0 pPIWI_RE module N-terminal domain SLC3A2_N PF16028.5 KIY62565.1 - 9.9 5.8 6.2 0.64 9.6 0.1 2.0 2 0 0 2 2 2 0 Solute carrier family 3 member 2 N-terminus zf-MYND PF01753.18 KIY62566.1 - 6.6e-06 26.1 10.5 1.1e-05 25.5 10.5 1.3 1 0 0 1 1 1 1 MYND finger DUF836 PF05768.14 KIY62567.1 - 3.6e-11 43.3 0.0 5.6e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) PSP PF04046.16 KIY62567.1 - 5e-06 26.3 0.2 5e-06 26.3 0.2 3.4 4 0 0 4 4 4 1 PSP zf-CCHC PF00098.23 KIY62567.1 - 4.6e-05 23.3 3.6 4.6e-05 23.3 3.6 1.8 2 0 0 2 2 2 1 Zinc knuckle Thioredoxin_3 PF13192.6 KIY62567.1 - 0.00095 19.2 0.0 0.0017 18.4 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin domain zf-CCCH PF00642.24 KIY62568.1 - 3.4e-06 26.8 1.4 5.4e-06 26.2 1.4 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KIY62568.1 - 0.00018 21.5 2.3 0.00027 20.9 2.3 1.3 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 KIY62568.1 - 0.0023 17.7 2.9 0.0036 17.1 2.9 1.3 1 0 0 1 1 1 1 CCCH-type zinc finger Torus PF16131.5 KIY62568.1 - 0.064 14.0 0.0 0.16 12.6 0.0 1.6 1 0 0 1 1 1 0 Torus domain AAA_5 PF07728.14 KIY62569.1 - 8e-11 42.1 0.0 1.8e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KIY62569.1 - 1.5e-07 31.7 0.0 3.6e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KIY62569.1 - 1.7e-05 25.1 0.0 4.3e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KIY62569.1 - 3.7e-05 24.2 0.0 0.0001 22.7 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KIY62569.1 - 0.0008 19.8 0.0 0.023 15.1 0.0 2.5 1 1 0 2 2 2 1 AAA ATPase domain TniB PF05621.11 KIY62569.1 - 0.0024 17.3 0.0 1.4 8.3 0.0 2.4 2 0 0 2 2 2 2 Bacterial TniB protein Mg_chelatase PF01078.21 KIY62569.1 - 0.0058 16.0 0.0 0.04 13.3 0.0 2.0 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 KIY62569.1 - 0.017 15.2 0.0 0.1 12.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_PrkA PF08298.11 KIY62569.1 - 0.02 13.8 0.0 0.03 13.2 0.0 1.3 1 0 0 1 1 1 0 PrkA AAA domain Sigma54_activat PF00158.26 KIY62569.1 - 0.044 13.5 0.0 0.092 12.5 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 KIY62569.1 - 0.047 13.4 0.0 0.094 12.4 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.22 KIY62569.1 - 0.05 14.0 0.0 0.16 12.4 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 KIY62569.1 - 0.073 12.6 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 KIY62569.1 - 0.14 12.3 0.1 0.4 10.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.27 KIY62570.1 - 1.5e-67 226.9 0.2 2.1e-67 226.4 0.2 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 KIY62570.1 - 7.8e-16 58.0 0.0 4.4e-15 55.5 0.0 2.2 2 0 0 2 2 2 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.25 KIY62570.1 - 2.6e-13 50.2 0.1 1.7e-12 47.5 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.6 KIY62570.1 - 4.9e-13 49.0 0.0 1.1e-12 47.9 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 KIY62570.1 - 7.2e-05 22.8 0.3 0.00016 21.8 0.3 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GST_N_3 PF13417.6 KIY62573.1 - 9.6e-12 45.2 0.1 1.8e-11 44.3 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KIY62573.1 - 5.4e-08 33.0 0.0 1e-07 32.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KIY62573.1 - 1.4e-05 25.3 0.0 2.9e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KIY62573.1 - 2e-05 24.7 0.0 0.00043 20.5 0.0 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KIY62573.1 - 9.6e-05 22.3 0.8 0.00029 20.8 0.1 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 KIY62573.1 - 0.0022 18.2 0.0 0.0043 17.2 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin GST_C_3 PF14497.6 KIY62573.1 - 0.0074 16.5 0.1 0.02 15.1 0.1 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KIY62573.1 - 0.008 16.7 0.0 0.014 16.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Exo_endo_phos PF03372.23 KIY62575.1 - 2.8e-10 40.1 0.0 5.3e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family WD40 PF00400.32 KIY62575.1 - 0.041 14.8 0.3 1.2 10.1 0.0 3.5 2 0 0 2 2 2 0 WD domain, G-beta repeat SecIII_SopE_N PF05364.14 KIY62576.1 - 0.12 12.5 0.1 0.24 11.5 0.1 1.4 1 0 0 1 1 1 0 Salmonella type III secretion SopE effector N-terminus Aldo_ket_red PF00248.21 KIY62577.1 - 3.2e-70 236.6 0.0 3.7e-70 236.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ThrE PF06738.12 KIY62579.1 - 3.6e-53 180.4 7.0 3.6e-53 180.4 7.0 2.6 2 1 0 2 2 2 1 Putative threonine/serine exporter ThrE_2 PF12821.7 KIY62579.1 - 3.6e-10 40.1 8.7 3.6e-10 40.1 8.7 2.6 2 0 0 2 2 2 1 Threonine/Serine exporter, ThrE DUF1356 PF07092.12 KIY62580.1 - 0.1 11.9 0.1 0.2 10.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1356) ThrE PF06738.12 KIY62581.1 - 6.7e-54 182.8 9.4 6.7e-54 182.8 9.4 2.2 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 KIY62581.1 - 2.6e-10 40.5 4.4 2.6e-10 40.5 4.4 2.4 2 0 0 2 2 2 1 Threonine/Serine exporter, ThrE Phage_holin_5_2 PF16079.5 KIY62581.1 - 0.043 14.2 1.0 3.8 7.9 0.0 2.9 2 0 0 2 2 2 0 Phage holin family Hol44, in holin superfamily V Sugar_tr PF00083.24 KIY62582.1 - 2.4e-126 422.2 23.7 2.8e-126 422.0 23.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY62582.1 - 9e-20 70.9 37.5 3.6e-14 52.5 17.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily OmdA PF13376.6 KIY62587.1 - 0.036 14.1 0.1 4.8 7.3 0.0 2.4 2 0 0 2 2 2 0 Bacteriocin-protection, YdeI or OmpD-Associated EcoEI_R_C PF08463.10 KIY62587.1 - 0.078 13.1 0.0 0.18 11.9 0.0 1.5 2 0 0 2 2 2 0 EcoEI R protein C-terminal Plavaka PF18759.1 KIY62588.1 - 8.2e-123 409.8 0.0 1.2e-122 409.2 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase zf-C2H2_4 PF13894.6 KIY62588.1 - 0.82 10.7 8.7 0.55 11.2 4.4 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KIY62588.1 - 8 7.1 9.9 11 6.8 4.5 3.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type DEAD PF00270.29 KIY62593.1 - 1.7e-17 63.8 0.0 2.7e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIY62593.1 - 3.7e-14 53.0 0.0 1.2e-13 51.3 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIY62593.1 - 5.4e-06 26.5 0.0 8.8e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PilW PF16074.5 KIY62598.1 - 0.12 12.4 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Type IV Pilus-assembly protein W Transposase_21 PF02992.14 KIY62599.1 - 3.5e-07 29.7 0.0 1.1e-06 28.0 0.0 1.8 2 0 0 2 2 2 1 Transposase family tnp2 AP1AR PF15745.5 KIY62599.1 - 0.023 14.4 3.6 0.038 13.6 3.6 1.3 1 0 0 1 1 1 0 AP-1 complex-associated regulatory protein Bac_rhamnosid_N PF08531.10 KIY62601.1 - 0.00017 21.4 0.4 0.07 12.9 0.2 2.9 1 1 1 2 2 2 2 Alpha-L-rhamnosidase N-terminal domain Latarcin PF10279.9 KIY62602.1 - 0.95 9.9 4.6 1.6 9.2 4.6 1.4 1 0 0 1 1 1 0 Latarcin precursor tRNA-synt_2 PF00152.20 KIY62603.1 - 1.3e-75 254.4 0.0 1.6e-75 254.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KIY62603.1 - 1.4e-13 50.6 0.1 6e-13 48.6 0.0 2.1 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KIY62603.1 - 8.2e-09 35.3 0.2 0.00033 20.2 0.0 3.0 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) IHABP4_N PF16174.5 KIY62603.1 - 1.7 9.2 7.7 0.16 12.6 1.6 2.0 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal Amidase PF01425.21 KIY62605.1 - 4.4e-100 335.8 0.0 5.7e-100 335.4 0.0 1.1 1 0 0 1 1 1 1 Amidase PKD_channel PF08016.12 KIY62606.1 - 0.0048 15.6 14.5 0.07 11.8 0.6 2.3 1 1 1 2 2 2 2 Polycystin cation channel Vps5 PF09325.10 KIY62607.1 - 3.9e-69 232.8 8.6 5.6e-69 232.3 8.6 1.2 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 KIY62607.1 - 3.6e-27 94.6 0.2 1e-25 89.9 0.0 2.4 2 0 0 2 2 2 1 PX domain Arfaptin PF06456.13 KIY62607.1 - 0.0018 17.9 3.6 0.0036 16.9 3.6 1.5 1 0 0 1 1 1 1 Arfaptin-like domain BAR_3_WASP_bdg PF10456.9 KIY62607.1 - 0.02 14.4 2.0 1.2 8.6 0.1 2.2 1 1 1 2 2 2 0 WASP-binding domain of Sorting nexin protein MTBP_mid PF14919.6 KIY62607.1 - 0.13 11.4 4.1 0.19 10.9 4.1 1.2 1 0 0 1 1 1 0 MDM2-binding BAR_3 PF16746.5 KIY62607.1 - 0.16 11.7 6.1 0.76 9.4 4.8 2.2 1 1 1 2 2 2 0 BAR domain of APPL family SlyX PF04102.12 KIY62607.1 - 3.8 8.2 5.6 6.8 7.4 2.0 3.1 2 1 1 3 3 3 0 SlyX Glyco_hydro_18 PF00704.28 KIY62608.1 - 3.8e-12 46.6 0.1 4.7e-12 46.3 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 PIN_10 PF18478.1 KIY62608.1 - 0.18 12.0 1.0 25 5.2 0.0 2.3 2 0 0 2 2 2 0 PIN like domain Pkinase PF00069.25 KIY62610.1 - 2.8e-71 240.0 0.0 3.9e-71 239.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY62610.1 - 1.7e-53 181.5 0.0 2.5e-53 181.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase CH PF00307.31 KIY62610.1 - 2.1e-08 34.3 0.0 4.2e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain C1_1 PF00130.22 KIY62610.1 - 3.3e-07 30.1 2.7 5.9e-07 29.3 2.7 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn_ribbon_17 PF17120.5 KIY62610.1 - 0.00016 21.2 2.6 0.00031 20.3 2.6 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type CDC24 PF06395.11 KIY62610.1 - 0.0021 18.3 0.0 0.0048 17.1 0.0 1.5 1 0 0 1 1 1 1 CDC24 Calponin Kinase-like PF14531.6 KIY62610.1 - 0.029 13.7 0.0 0.15 11.3 0.0 1.9 2 0 0 2 2 2 0 Kinase-like RIO1 PF01163.22 KIY62610.1 - 0.044 13.4 0.1 0.083 12.5 0.1 1.4 1 0 0 1 1 1 0 RIO1 family Seadorna_VP7 PF07387.11 KIY62610.1 - 0.087 11.9 0.1 0.13 11.2 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 YrbL-PhoP_reg PF10707.9 KIY62610.1 - 0.11 12.0 0.0 0.27 10.7 0.1 1.5 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL PHD PF00628.29 KIY62610.1 - 0.79 9.7 4.2 1.5 8.7 4.2 1.4 1 0 0 1 1 1 0 PHD-finger TFIIS_M PF07500.14 KIY62611.1 - 5.3e-17 62.3 0.4 9.2e-17 61.5 0.4 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain SPOC PF07744.13 KIY62611.1 - 4.1e-07 30.0 0.0 9e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 SPOC domain PHD PF00628.29 KIY62611.1 - 2e-05 24.4 3.2 3.2e-05 23.7 3.2 1.3 1 0 0 1 1 1 1 PHD-finger SEEEED PF14797.6 KIY62611.1 - 0.33 11.1 7.2 0.3 11.3 2.9 2.2 2 0 0 2 2 2 0 Serine-rich region of AP3B1, clathrin-adaptor complex Dynactin_p22 PF07426.11 KIY62612.1 - 9e-17 61.4 0.0 1.4e-16 60.8 0.0 1.3 1 0 0 1 1 1 1 Dynactin subunit p22 MetOD2 PF18548.1 KIY62612.1 - 0.047 13.8 0.4 0.15 12.2 0.1 1.9 2 0 0 2 2 2 0 Metanogen output domain 2 Lebercilin PF15619.6 KIY62612.1 - 0.067 12.8 6.3 0.43 10.2 3.1 2.7 2 1 1 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Golgin_A5 PF09787.9 KIY62612.1 - 0.07 12.6 0.6 0.1 12.0 0.6 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 Syntaxin-6_N PF09177.11 KIY62612.1 - 0.093 13.3 0.3 0.63 10.6 0.1 2.5 1 1 2 3 3 3 0 Syntaxin 6, N-terminal RD3 PF14473.6 KIY62612.1 - 0.13 12.1 0.3 0.27 11.1 0.3 1.5 1 0 0 1 1 1 0 RD3 protein APG6_N PF17675.1 KIY62612.1 - 0.27 11.7 2.8 2.8 8.5 0.0 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region Pkinase_Tyr PF07714.17 KIY62613.1 - 6.6e-26 91.1 0.0 1.1e-25 90.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIY62613.1 - 7.2e-25 87.8 0.0 1.1e-24 87.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KIY62613.1 - 0.00078 18.3 0.0 0.0012 17.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase DEP PF00610.21 KIY62613.1 - 0.00088 19.3 0.0 0.0022 18.0 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) APH PF01636.23 KIY62613.1 - 0.036 14.0 0.4 0.06 13.3 0.4 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family RRM_1 PF00076.22 KIY62615.1 - 1e-10 41.2 0.1 7.4e-08 32.1 0.1 2.8 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_hydro_28 PF00295.17 KIY62616.1 - 7.4e-56 189.6 19.4 8.9e-56 189.3 19.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 NosD PF05048.13 KIY62616.1 - 1.3e-06 27.8 13.8 1.3e-06 27.8 13.8 1.6 1 1 1 2 2 2 1 Periplasmic copper-binding protein (NosD) ArfGap PF01412.18 KIY62617.1 - 6.9e-37 126.1 0.2 1.3e-36 125.3 0.2 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf DUF5572 PF17733.1 KIY62618.1 - 1.1e-16 60.4 0.9 1.4e-16 60.0 0.2 1.6 2 0 0 2 2 2 1 Family of unknown function (DUF5572) Toprim_Crpt PF13342.6 KIY62618.1 - 0.095 12.7 0.0 1.3 9.1 0.0 2.1 2 0 0 2 2 2 0 C-terminal repeat of topoisomerase Epimerase PF01370.21 KIY62619.1 - 3.1e-50 170.9 0.3 6.7e-50 169.8 0.0 1.6 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KIY62619.1 - 6.1e-17 62.0 0.0 6.1e-17 62.0 0.0 1.5 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KIY62619.1 - 0.00016 20.9 0.0 0.00086 18.5 0.0 2.0 2 0 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KIY62619.1 - 0.00024 20.3 1.8 0.0022 17.2 1.5 2.6 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 KIY62619.1 - 0.086 11.8 0.1 0.25 10.3 0.1 1.7 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family TSNR_N PF04705.12 KIY62619.1 - 0.18 11.9 0.0 0.34 11.0 0.0 1.4 1 0 0 1 1 1 0 Thiostrepton-resistance methylase, N terminus PAPS_reduct PF01507.19 KIY62620.1 - 6.5e-25 88.2 0.0 6.7e-24 84.9 0.0 2.0 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Pkinase PF00069.25 KIY62622.1 - 7.5e-48 163.2 0.0 1.4e-47 162.3 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY62622.1 - 1.3e-30 106.6 0.0 3.4e-30 105.2 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase FHA PF00498.26 KIY62622.1 - 2.4e-10 40.6 0.2 5e-10 39.6 0.2 1.6 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KIY62622.1 - 1.8e-06 28.2 0.0 4.4e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Kinase-like PF14531.6 KIY62622.1 - 5e-05 22.8 0.0 0.00019 20.9 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KIY62622.1 - 0.0092 15.9 0.2 0.074 13.0 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family 2-oxoacid_dh PF00198.23 KIY62624.1 - 3.9e-50 170.5 0.0 6.9e-49 166.4 0.0 2.4 2 1 0 2 2 2 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KIY62624.1 - 3e-18 65.4 0.3 6.5e-18 64.3 0.1 1.7 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.17 KIY62624.1 - 3.7e-11 43.2 0.0 8.6e-11 42.0 0.0 1.7 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 KIY62624.1 - 0.00075 19.3 0.2 0.0016 18.2 0.2 1.5 1 0 0 1 1 1 1 Biotin-lipoyl like Wyosine_form PF08608.12 KIY62624.1 - 0.023 15.0 0.0 0.085 13.2 0.0 1.9 2 0 0 2 2 2 0 Wyosine base formation HlyD_D23 PF16576.5 KIY62624.1 - 0.026 13.7 0.0 0.045 13.0 0.0 1.3 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 KIY62624.1 - 0.047 14.4 0.0 0.21 12.3 0.0 2.1 3 0 0 3 3 3 0 HlyD family secretion protein DUF4218 PF13960.6 KIY62627.1 - 0.013 15.1 0.1 0.019 14.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) LIME1 PF15332.6 KIY62629.1 - 0.016 14.8 0.3 0.022 14.4 0.3 1.2 1 0 0 1 1 1 0 Lck-interacting transmembrane adapter 1 KdpD PF02702.17 KIY62629.1 - 0.02 14.4 0.2 0.033 13.6 0.1 1.5 1 1 0 1 1 1 0 Osmosensitive K+ channel His kinase sensor domain Golgin_A5 PF09787.9 KIY62630.1 - 0.007 15.9 23.4 0.009 15.5 22.8 1.4 1 1 0 1 1 1 1 Golgin subfamily A member 5 DUF812 PF05667.11 KIY62630.1 - 0.014 14.3 15.5 0.017 14.0 15.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Fez1 PF06818.15 KIY62630.1 - 0.018 15.5 20.9 1 9.8 7.4 2.2 1 1 1 2 2 2 0 Fez1 Spc7 PF08317.11 KIY62630.1 - 0.029 13.3 19.9 0.042 12.7 19.9 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein TMPIT PF07851.13 KIY62630.1 - 0.23 10.7 17.0 0.47 9.6 8.1 2.1 1 1 1 2 2 2 0 TMPIT-like protein Exonuc_VII_L PF02601.15 KIY62630.1 - 0.24 11.0 20.9 0.36 10.3 19.8 1.7 1 1 1 2 2 2 0 Exonuclease VII, large subunit Atg14 PF10186.9 KIY62630.1 - 0.55 9.3 19.3 0.96 8.5 19.3 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 CCDC-167 PF15188.6 KIY62630.1 - 0.64 10.4 17.0 52 4.3 16.3 2.9 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 TMF_TATA_bd PF12325.8 KIY62630.1 - 0.69 10.2 17.9 0.2 11.9 6.1 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF572 PF04502.13 KIY62630.1 - 0.84 9.2 14.0 1.1 8.7 14.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) ApoO PF09769.9 KIY62630.1 - 0.85 9.6 3.4 1.9 8.4 0.7 2.7 2 1 1 3 3 3 0 Apolipoprotein O LMBR1 PF04791.16 KIY62630.1 - 1.1 8.1 11.0 1.5 7.7 11.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF3450 PF11932.8 KIY62630.1 - 1.2 8.4 23.6 5.7 6.2 8.5 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) APG6_N PF17675.1 KIY62630.1 - 1.3 9.6 25.0 6.8 7.2 8.4 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region Tropomyosin_1 PF12718.7 KIY62630.1 - 1.8 8.7 22.4 1.1 9.5 9.8 2.2 1 1 1 2 2 2 0 Tropomyosin like V_ATPase_I PF01496.19 KIY62630.1 - 2.3 6.1 9.3 3.2 5.5 9.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family 5_nucleotid PF05761.14 KIY62630.1 - 2.4 7.0 6.2 3.8 6.3 6.2 1.4 1 0 0 1 1 1 0 5' nucleotidase family ADIP PF11559.8 KIY62630.1 - 3.5 7.7 28.5 5.5 7.1 20.6 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding XhlA PF10779.9 KIY62630.1 - 4.8 7.5 16.7 1.3 9.3 2.7 3.2 1 1 1 3 3 3 0 Haemolysin XhlA Fib_alpha PF08702.10 KIY62630.1 - 4.9 7.3 17.0 12 6.1 10.0 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF3037 PF11236.8 KIY62630.1 - 5.3 7.5 6.2 53 4.3 6.2 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3037) DUF4200 PF13863.6 KIY62630.1 - 6.1 7.3 21.8 0.71 10.3 8.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Metal_resist PF13801.6 KIY62630.1 - 7.8 6.7 13.0 41 4.4 13.4 2.0 2 0 0 2 2 2 0 Heavy-metal resistance F-box-like PF12937.7 KIY62632.1 - 2e-05 24.4 3.6 4.1e-05 23.4 2.8 2.0 2 0 0 2 2 2 1 F-box-like F-box-like_2 PF13013.6 KIY62632.1 - 0.013 15.4 0.1 0.028 14.4 0.1 1.5 1 0 0 1 1 1 0 F-box-like domain NCE101 PF11654.8 KIY62632.1 - 0.19 11.4 0.3 0.81 9.4 0.1 2.1 2 0 0 2 2 2 0 Non-classical export protein 1 F-box-like PF12937.7 KIY62633.1 - 0.0012 18.7 0.4 0.0036 17.1 0.4 1.8 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KIY62634.1 - 0.0032 17.8 0.0 0.77 10.3 0.3 3.6 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) TB2_DP1_HVA22 PF03134.19 KIY62635.1 - 1.5e-22 79.3 2.8 1.5e-22 79.3 2.8 1.5 2 0 0 2 2 2 1 TB2/DP1, HVA22 family Chromate_transp PF02417.15 KIY62635.1 - 1.7 8.8 5.4 16 5.6 1.6 2.1 1 1 0 2 2 2 0 Chromate transporter Zn_clus PF00172.18 KIY62636.1 - 2.3e-07 30.8 10.7 4.5e-07 29.9 10.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KIY62636.1 - 4.1e-07 29.3 0.1 7.3e-07 28.5 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain F-box-like PF12937.7 KIY62637.1 - 0.03 14.2 0.4 0.18 11.7 0.2 2.5 2 0 0 2 2 2 0 F-box-like F-box-like PF12937.7 KIY62638.1 - 1e-06 28.5 1.1 1e-06 28.5 1.1 2.4 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 KIY62640.1 - 7.7e-08 32.1 0.2 1.7e-07 31.0 0.2 1.6 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KIY62640.1 - 0.00051 20.4 0.1 2 9.0 0.1 3.2 2 1 0 2 2 2 2 Leucine Rich repeats (2 copies) F-box PF00646.33 KIY62640.1 - 0.026 14.4 2.4 0.64 10.0 2.4 2.7 1 1 0 1 1 1 0 F-box domain LIDHydrolase PF10230.9 KIY62641.1 - 1.1e-36 126.8 0.0 1.3e-36 126.5 0.0 1.1 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Hydrolase_4 PF12146.8 KIY62641.1 - 3.1e-10 39.7 0.0 3.9e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KIY62641.1 - 0.0011 18.7 0.0 0.0022 17.7 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF900 PF05990.12 KIY62641.1 - 0.026 14.0 0.1 0.17 11.4 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) Sec8_exocyst PF04048.14 KIY62642.1 - 4.4e-37 127.1 0.9 1.4e-36 125.5 0.9 1.9 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 KIY62642.1 - 6.9e-07 28.8 0.9 1.6e-06 27.7 0.9 1.5 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Esterase PF00756.20 KIY62643.1 - 2.5e-40 138.7 0.0 2.8e-40 138.5 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 KIY62643.1 - 0.0083 15.4 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KIY62643.1 - 0.013 15.0 0.0 0.018 14.5 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Esterase_phd PF10503.9 KIY62643.1 - 0.053 13.0 0.0 0.086 12.3 0.0 1.3 1 0 0 1 1 1 0 Esterase PHB depolymerase Chlorophyllase2 PF12740.7 KIY62643.1 - 0.085 11.7 0.0 0.17 10.8 0.0 1.6 1 1 0 1 1 1 0 Chlorophyllase enzyme Aldo_ket_red PF00248.21 KIY62645.1 - 3.8e-46 157.6 0.0 2.2e-44 151.9 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Sugar_tr PF00083.24 KIY62646.1 - 1e-85 288.3 22.9 1.2e-85 288.1 22.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY62646.1 - 5.7e-24 84.7 38.9 1.5e-20 73.5 22.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2471 PF10616.9 KIY62647.1 - 0.04 14.5 0.6 0.65 10.6 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2471) Histone PF00125.24 KIY62649.1 - 2.5e-17 63.4 0.0 2.9e-17 63.3 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 KIY62649.1 - 5e-16 58.1 1.6 1e-15 57.1 1.6 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 KIY62649.1 - 1.3e-06 28.5 0.0 1.8e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Pkinase PF00069.25 KIY62650.1 - 6.4e-72 242.1 1.6 1.4e-71 241.0 0.1 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY62650.1 - 2.8e-50 171.0 1.2 3.6e-50 170.6 0.2 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.28 KIY62650.1 - 1.5e-23 82.9 0.0 3.6e-23 81.7 0.0 1.7 1 0 0 1 1 1 1 P21-Rho-binding domain PH PF00169.29 KIY62650.1 - 2.8e-08 34.2 0.7 6.8e-08 33.0 0.7 1.6 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 KIY62650.1 - 7.8e-06 25.4 0.0 2.1e-05 24.0 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KIY62650.1 - 5.3e-05 22.2 0.0 9.4e-05 21.4 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KIY62650.1 - 0.00047 19.2 1.6 0.001 18.1 1.6 1.4 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KIY62650.1 - 0.0055 16.7 0.1 0.095 12.6 0.1 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KIY62650.1 - 0.0063 15.6 0.3 0.013 14.6 0.3 1.4 1 0 0 1 1 1 1 Seadornavirus VP7 TPR_8 PF13181.6 KIY62652.1 - 3.4e-10 39.3 0.5 0.0056 16.8 0.0 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 KIY62652.1 - 5.2e-10 38.7 0.2 0.0015 18.2 0.0 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 KIY62652.1 - 6.1e-09 35.3 18.9 0.00085 19.3 0.0 8.7 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_14 PF13428.6 KIY62652.1 - 9.1e-06 26.1 25.4 0.038 14.8 0.9 7.2 6 2 2 8 8 8 4 Tetratricopeptide repeat TPR_11 PF13414.6 KIY62652.1 - 0.00044 19.9 0.4 0.61 9.8 0.0 4.7 4 1 1 5 5 5 1 TPR repeat TPR_19 PF14559.6 KIY62652.1 - 0.0066 16.9 12.1 0.61 10.6 0.0 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 KIY62652.1 - 0.047 13.7 0.0 7.6 6.8 0.0 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 KIY62652.1 - 0.15 12.5 1.5 36 5.1 0.0 5.0 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 KIY62652.1 - 0.34 11.6 28.4 1.9 9.2 0.4 6.8 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 KIY62652.1 - 0.85 9.9 17.7 0.85 9.9 0.1 6.2 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.6 KIY62652.1 - 0.98 10.2 16.4 43 5.0 0.3 6.4 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_9 PF13371.6 KIY62652.1 - 2.3 8.4 9.7 11 6.3 0.3 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat PIG-F PF06699.11 KIY62655.1 - 0.062 13.5 0.1 0.09 12.9 0.1 1.3 1 0 0 1 1 1 0 GPI biosynthesis protein family Pig-F Peptidase_C14 PF00656.22 KIY62656.1 - 1.3e-56 192.3 0.0 1.7e-56 191.9 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.6 KIY62656.1 - 0.13 12.2 0.2 6.7 6.6 0.1 2.6 2 0 0 2 2 2 0 Raptor N-terminal CASPase like domain MFS_1 PF07690.16 KIY62657.1 - 2e-30 105.9 12.3 2e-30 105.9 12.3 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 KIY62657.1 - 1.8e-05 24.3 6.3 0.00081 18.8 0.2 3.0 3 0 0 3 3 3 3 Uncharacterised MFS-type transporter YbfB TEA PF01285.18 KIY62658.1 - 2e-20 72.6 0.1 3.8e-20 71.7 0.1 1.5 1 0 0 1 1 1 1 TEA/ATTS domain RabGAP-TBC PF00566.18 KIY62659.1 - 6.7e-48 163.2 0.0 1e-47 162.6 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_7 PF13499.6 KIY62659.1 - 3.1e-05 24.3 0.3 0.00065 20.1 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KIY62659.1 - 0.00028 20.6 3.8 0.0013 18.5 0.5 3.0 3 0 0 3 3 3 1 EF-hand domain GRAM PF02893.20 KIY62659.1 - 0.00035 20.4 0.0 0.00082 19.2 0.0 1.6 1 0 0 1 1 1 1 GRAM domain EF-hand_1 PF00036.32 KIY62659.1 - 0.00042 19.7 2.5 0.0013 18.1 0.2 2.8 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 KIY62659.1 - 0.039 13.5 0.4 0.17 11.5 0.1 2.2 2 0 0 2 2 2 0 EF hand EF-hand_8 PF13833.6 KIY62659.1 - 0.15 12.0 1.3 4.4 7.2 0.2 2.9 2 0 0 2 2 2 0 EF-hand domain pair BTB PF00651.31 KIY62660.1 - 0.00046 20.4 0.0 0.0011 19.2 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain IL2RB_N1 PF18707.1 KIY62660.1 - 0.073 13.6 0.3 0.073 13.6 0.3 1.6 2 0 0 2 2 2 0 Interleukin-2 receptor subunit beta N-terminal domain 1 Sugar_tr PF00083.24 KIY62664.1 - 9.4e-100 334.6 19.1 1.1e-99 334.4 19.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY62664.1 - 6.4e-23 81.2 40.6 6.5e-16 58.2 7.2 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KIY62664.1 - 0.00099 17.5 0.8 0.00099 17.5 0.8 2.1 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Septin PF00735.18 KIY62665.1 - 2.2e-47 161.7 0.0 6.6e-18 65.0 0.0 3.6 4 0 0 4 4 4 3 Septin MMR_HSR1 PF01926.23 KIY62665.1 - 0.00017 21.7 0.0 0.00036 20.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KIY62665.1 - 0.0041 17.5 1.1 0.025 15.0 1.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain GTP_EFTU PF00009.27 KIY62665.1 - 0.0048 16.5 0.0 0.011 15.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 KIY62665.1 - 0.0093 16.2 0.0 0.023 15.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KIY62665.1 - 0.096 12.9 0.1 0.25 11.6 0.1 1.7 1 0 0 1 1 1 0 AAA domain zf-H2C2_5 PF13909.6 KIY62665.1 - 0.14 11.9 0.4 0.32 10.8 0.4 1.7 1 0 0 1 1 1 0 C2H2-type zinc-finger domain ABC_tran PF00005.27 KIY62665.1 - 0.17 12.4 0.1 0.47 11.0 0.1 1.8 1 1 0 1 1 1 0 ABC transporter Dynamin_N PF00350.23 KIY62665.1 - 0.18 11.8 0.4 7 6.7 0.1 2.4 1 1 1 2 2 2 0 Dynamin family Pox_A32 PF04665.12 KIY62665.1 - 0.2 11.1 0.0 0.3 10.5 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein Septin PF00735.18 KIY62666.1 - 4.3e-25 88.5 0.0 3.4e-09 36.4 0.0 3.1 3 0 0 3 3 3 3 Septin Zn_clus PF00172.18 KIY62666.1 - 2.7e-19 69.0 26.5 1.2e-09 38.1 7.5 2.4 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain ATG27 PF09451.10 KIY62666.1 - 2.7 7.8 5.9 0.77 9.6 0.9 2.0 2 0 0 2 2 2 0 Autophagy-related protein 27 zf-MYND PF01753.18 KIY62667.1 - 1.6e-07 31.3 10.4 4.1e-07 30.0 10.4 1.7 1 0 0 1 1 1 1 MYND finger Zn_clus PF00172.18 KIY62668.1 - 3.5e-10 39.8 8.6 5.5e-10 39.2 8.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Vma12 PF11712.8 KIY62668.1 - 0.084 12.9 0.8 0.18 11.9 0.8 1.5 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase ILVD_EDD PF00920.21 KIY62669.1 - 2.8e-207 689.4 0.1 3.3e-207 689.2 0.1 1.0 1 0 0 1 1 1 1 Dehydratase family DUF3376 PF11856.8 KIY62669.1 - 0.19 10.7 0.0 0.27 10.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3376) DUF2451 PF10474.9 KIY62677.1 - 0.046 13.5 0.2 0.059 13.2 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2451) adh_short_C2 PF13561.6 KIY62680.1 - 7.8e-58 195.8 4.3 1.7e-55 188.1 2.3 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIY62680.1 - 5.4e-46 156.5 4.5 5.4e-46 156.5 4.5 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KIY62680.1 - 2.2e-05 24.5 1.9 3.4e-05 23.8 1.9 1.2 1 0 0 1 1 1 1 KR domain Ribosomal_L12_N PF16320.5 KIY62680.1 - 0.017 14.8 0.1 0.047 13.4 0.1 1.7 1 0 0 1 1 1 0 Ribosomal protein L7/L12 dimerisation domain adh_short_C2 PF13561.6 KIY62681.1 - 3.3e-100 334.5 3.9 3.2e-56 190.5 0.3 4.0 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIY62681.1 - 6.5e-88 293.3 11.1 2.4e-49 167.4 1.6 3.0 3 0 0 3 3 3 3 short chain dehydrogenase KR PF08659.10 KIY62681.1 - 2.7e-14 53.5 2.1 4.2e-06 26.8 0.4 2.4 2 0 0 2 2 2 2 KR domain NinF PF05810.12 KIY62681.1 - 0.0063 16.3 0.8 5.8 6.9 0.1 2.9 3 0 0 3 3 3 2 NinF protein Epimerase PF01370.21 KIY62681.1 - 0.0091 15.5 1.5 6 6.3 0.1 4.0 4 0 0 4 4 4 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 KIY62681.1 - 0.049 13.5 0.5 0.5 10.2 0.1 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Metallophos_2 PF12850.7 KIY62681.1 - 0.11 12.7 0.0 3.4 7.8 0.0 2.2 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain adh_short_C2 PF13561.6 KIY62682.1 - 9.3e-54 182.4 0.7 8.1e-52 176.1 0.7 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIY62682.1 - 3.4e-49 167.0 1.0 4.3e-49 166.6 1.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIY62682.1 - 6.9e-10 39.1 0.8 9.1e-10 38.7 0.8 1.2 1 0 0 1 1 1 1 KR domain 4HB_MCP_1 PF12729.7 KIY62682.1 - 0.061 12.9 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction Aldolase PF01081.19 KIY62682.1 - 0.096 12.1 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 KDPG and KHG aldolase DUF1077 PF06417.12 KIY62683.1 - 1.6e-45 153.9 0.2 2.2e-45 153.5 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) F-box-like PF12937.7 KIY62684.1 - 8.2e-07 28.8 3.2 3.5e-06 26.8 3.2 2.1 1 1 0 1 1 1 1 F-box-like LRRNT PF01462.18 KIY62684.1 - 0.042 13.5 1.1 1.9 8.2 0.0 3.4 3 0 0 3 3 3 0 Leucine rich repeat N-terminal domain CsbD PF05532.12 KIY62685.1 - 2e-09 37.2 14.6 5.3e-08 32.7 3.3 2.3 1 1 1 2 2 2 2 CsbD-like HSP9_HSP12 PF04119.12 KIY62685.1 - 0.071 13.5 0.2 0.28 11.6 0.0 2.0 2 0 0 2 2 2 0 Heat shock protein 9/12 CsbD PF05532.12 KIY62687.1 - 8.1e-14 51.3 18.3 1.1e-08 34.8 3.1 2.1 1 1 1 2 2 2 2 CsbD-like PIF1 PF05970.14 KIY62691.1 - 1.7e-06 27.5 0.2 4.4e-06 26.1 0.0 1.7 2 0 0 2 2 2 1 PIF1-like helicase DUF5634_N PF18672.1 KIY62691.1 - 0.051 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5634) PIF1 PF05970.14 KIY62692.1 - 9.7e-14 51.3 0.0 1.2e-13 51.0 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KIY62692.1 - 8e-11 42.0 0.0 9.8e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KIY62692.1 - 2e-07 31.4 0.0 3.7e-07 30.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KIY62692.1 - 0.00012 22.5 0.0 0.00013 22.5 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain ResIII PF04851.15 KIY62692.1 - 0.0012 18.9 0.0 0.0013 18.7 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Inhibitor_I9 PF05922.16 KIY62692.1 - 0.0044 17.7 0.0 0.009 16.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 AAA_22 PF13401.6 KIY62692.1 - 0.0055 17.0 0.0 0.011 16.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.17 KIY62692.1 - 0.0059 16.4 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_5 PF07728.14 KIY62692.1 - 0.0099 15.9 0.0 0.042 13.8 0.0 2.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) MeaB PF03308.16 KIY62692.1 - 0.024 13.6 0.0 0.03 13.3 0.0 1.1 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_PrkA PF08298.11 KIY62692.1 - 0.035 13.0 0.0 0.057 12.3 0.0 1.3 2 0 0 2 2 2 0 PrkA AAA domain Sigma54_activat PF00158.26 KIY62692.1 - 0.039 13.7 0.1 0.085 12.6 0.1 1.5 1 1 0 1 1 1 0 Sigma-54 interaction domain cobW PF02492.19 KIY62692.1 - 0.045 13.3 0.0 0.066 12.8 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain SMC_N PF02463.19 KIY62692.1 - 0.053 13.0 0.0 0.073 12.5 0.0 1.2 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KIY62692.1 - 0.069 12.9 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.6 KIY62692.1 - 0.098 12.4 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 KIY62692.1 - 0.1 13.2 0.0 0.19 12.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain T2SSE PF00437.20 KIY62692.1 - 0.12 11.4 0.0 0.15 11.0 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein Zeta_toxin PF06414.12 KIY62692.1 - 0.13 11.6 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin DEAD PF00270.29 KIY62692.1 - 0.14 11.9 0.0 0.55 10.0 0.0 1.8 1 1 1 2 2 2 0 DEAD/DEAH box helicase Helitron_like_N PF14214.6 KIY62695.1 - 3e-22 79.8 0.0 3.7e-22 79.5 0.0 1.0 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus LSM_int_assoc PF16605.5 KIY62697.1 - 0.0027 17.8 0.1 0.0062 16.6 0.1 1.7 1 0 0 1 1 1 1 LSM-interacting associated unstructured RTC4 PF14474.6 KIY62698.1 - 2.9e-19 69.4 0.0 4.5e-19 68.8 0.0 1.3 1 0 0 1 1 1 1 RTC4-like domain DUF5034 PF16437.5 KIY62699.1 - 0.13 12.3 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5034) Chromo PF00385.24 KIY62702.1 - 0.14 12.1 0.0 0.33 10.9 0.0 1.7 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain PIP5K PF01504.18 KIY62704.1 - 0.047 12.9 0.8 0.092 12.0 0.8 1.5 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase AAA_assoc_2 PF16193.5 KIY62704.1 - 0.061 13.7 0.0 0.15 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA C-terminal domain NAM-associated PF14303.6 KIY62704.1 - 0.57 10.9 0.0 0.57 10.9 0.0 3.6 3 1 0 4 4 4 0 No apical meristem-associated C-terminal domain bZIP_1 PF00170.21 KIY62708.1 - 5.3e-07 29.6 7.8 1.5e-06 28.2 7.8 1.8 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KIY62708.1 - 0.0017 18.4 11.3 0.02 15.0 4.1 2.4 1 1 1 2 2 2 2 Basic region leucine zipper Ribosomal_60s PF00428.19 KIY62708.1 - 0.12 13.0 10.6 0.8 10.3 4.9 3.5 3 0 0 3 3 3 0 60s Acidic ribosomal protein YabA PF06156.13 KIY62708.1 - 0.16 12.6 0.1 0.39 11.4 0.1 1.6 1 0 0 1 1 1 0 Initiation control protein YabA DUF3584 PF12128.8 KIY62708.1 - 0.21 9.1 3.2 0.29 8.6 3.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) HALZ PF02183.18 KIY62708.1 - 0.24 11.6 0.8 0.45 10.8 0.0 1.8 2 0 0 2 2 2 0 Homeobox associated leucine zipper bZIP_Maf PF03131.17 KIY62708.1 - 0.57 10.7 3.7 1.2 9.7 3.7 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor F-box-like PF12937.7 KIY62709.1 - 6e-07 29.2 3.1 7.2e-07 29.0 0.7 2.4 2 1 0 2 2 2 1 F-box-like F-box PF00646.33 KIY62709.1 - 1.7 8.6 7.4 2.3 8.2 0.4 3.3 4 0 0 4 4 4 0 F-box domain FeS_assembly_P PF01883.19 KIY62710.1 - 1.7e-14 53.8 0.1 3.2e-14 52.9 0.0 1.5 2 0 0 2 2 2 1 Iron-sulfur cluster assembly protein HpcH_HpaI PF03328.14 KIY62711.1 - 4.9e-18 65.1 0.2 6.6e-18 64.7 0.2 1.2 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Peptidase_S55 PF05580.12 KIY62711.1 - 0.012 15.5 0.0 0.022 14.7 0.0 1.3 1 0 0 1 1 1 0 SpoIVB peptidase S55 Aldo_ket_red PF00248.21 KIY62711.1 - 0.021 14.0 0.0 0.068 12.4 0.0 1.8 2 0 0 2 2 2 0 Aldo/keto reductase family HpcH_HpaI PF03328.14 KIY62712.1 - 1.9e-27 95.8 0.1 3.7e-27 94.9 0.0 1.3 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PK PF00224.21 KIY62712.1 - 0.0027 16.7 0.2 0.0046 15.9 0.2 1.3 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain Cullin_binding PF03556.15 KIY62713.1 - 4.9e-25 88.3 0.5 4.9e-25 88.3 0.5 1.6 2 0 0 2 2 2 1 Cullin binding NTF2 PF02136.20 KIY62714.1 - 4.3e-29 101.5 0.0 4.7e-29 101.4 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Opi1 PF08618.10 KIY62715.1 - 5.3e-60 203.8 5.5 2.2e-56 191.9 5.5 2.0 1 1 0 1 1 1 1 Transcription factor Opi1 Glyco_hydro_88 PF07470.13 KIY62716.1 - 1.2e-14 54.2 0.6 2.1e-14 53.4 0.6 1.4 1 1 0 1 1 1 1 Glycosyl Hydrolase Family 88 GlcNAc_2-epim PF07221.11 KIY62716.1 - 0.00088 18.6 0.1 0.0061 15.9 0.1 2.0 1 1 1 2 2 2 1 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) Glyco_hydro_127 PF07944.12 KIY62716.1 - 0.0015 17.2 0.0 0.042 12.3 0.0 2.3 1 1 1 2 2 2 2 Beta-L-arabinofuranosidase, GH127 C5-epim_C PF06662.13 KIY62716.1 - 0.003 17.1 0.2 0.2 11.1 0.0 2.6 2 1 0 3 3 3 1 D-glucuronyl C5-epimerase C-terminus LANC_like PF05147.13 KIY62717.1 - 2.1e-37 128.5 0.1 3.1e-37 128.0 0.1 1.2 1 0 0 1 1 1 1 Lanthionine synthetase C-like protein TPR_12 PF13424.6 KIY62717.1 - 0.02 15.2 1.8 0.063 13.6 0.6 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat KxDL PF10241.9 KIY62718.1 - 0.0035 17.6 0.9 0.74 10.1 0.4 2.4 2 1 0 2 2 2 2 Uncharacterized conserved protein DUF842 PF05811.13 KIY62718.1 - 0.064 12.9 0.1 0.078 12.7 0.1 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) F-box-like PF12937.7 KIY62719.1 - 2.2e-10 40.3 1.7 4.2e-10 39.4 0.2 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIY62719.1 - 2e-05 24.3 1.5 9.7e-05 22.1 0.9 2.6 2 1 0 2 2 2 1 F-box domain LRR_4 PF12799.7 KIY62719.1 - 0.01 16.2 9.5 0.71 10.4 0.1 4.3 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) Nuc_rec_co-act PF08815.10 KIY62719.1 - 0.16 11.8 1.0 2.5 8.0 0.0 2.7 2 0 0 2 2 2 0 Nuclear receptor coactivator zf-RING_2 PF13639.6 KIY62720.1 - 8.2e-09 35.7 5.9 2.2e-08 34.3 2.0 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KIY62720.1 - 1.8e-06 27.7 9.2 9.7e-06 25.3 4.1 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KIY62720.1 - 2.4e-06 27.7 8.9 1.1e-05 25.6 8.9 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 KIY62720.1 - 2.8e-06 26.9 4.8 0.0012 18.5 0.4 2.5 2 0 0 2 2 2 2 RING-like zinc finger zf-C3HC4 PF00097.25 KIY62720.1 - 4.7e-05 23.2 2.8 0.00014 21.7 2.8 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIY62720.1 - 0.00094 19.1 3.8 0.0025 17.8 3.8 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KIY62720.1 - 0.0016 18.2 1.5 0.0016 18.2 1.5 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KIY62720.1 - 0.0019 18.0 1.6 0.0019 18.0 1.6 1.9 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KIY62720.1 - 0.0023 18.0 1.1 0.005 16.9 1.1 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 KIY62720.1 - 0.0032 17.5 1.6 0.017 15.2 1.7 2.2 1 1 0 1 1 1 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 KIY62720.1 - 0.012 15.3 1.5 0.028 14.1 1.5 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3H2C3 PF17122.5 KIY62720.1 - 0.31 11.1 4.4 0.23 11.5 2.0 2.1 2 0 0 2 2 2 0 Zinc-finger zf-P11 PF03854.14 KIY62720.1 - 0.37 10.5 3.5 0.94 9.2 3.5 1.6 1 0 0 1 1 1 0 P-11 zinc finger DUF2070 PF09843.9 KIY62720.1 - 1.7 6.8 5.5 2.4 6.3 5.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) FANCL_C PF11793.8 KIY62720.1 - 1.9 8.8 5.4 4.2 7.6 3.3 2.5 2 1 0 2 2 2 0 FANCL C-terminal domain zf-RING_4 PF14570.6 KIY62720.1 - 2 8.3 5.0 0.48 10.3 1.3 1.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain RINGv PF12906.7 KIY62720.1 - 5 7.3 8.8 0.31 11.2 3.2 1.8 2 0 0 2 2 2 0 RING-variant domain Nnf1 PF03980.14 KIY62721.1 - 2.5e-14 53.6 2.4 4.3e-14 52.8 2.4 1.3 1 0 0 1 1 1 1 Nnf1 EcoR124_C PF12008.8 KIY62721.1 - 0.062 13.0 3.1 0.14 11.8 3.1 1.6 1 1 0 1 1 1 0 Type I restriction and modification enzyme - subunit R C terminal Glyco_hydro_127 PF07944.12 KIY62722.1 - 1.1e-17 63.7 0.0 2.9e-17 62.4 0.0 1.6 2 0 0 2 2 2 1 Beta-L-arabinofuranosidase, GH127 Glyco_hydro_71 PF03659.14 KIY62723.1 - 5.9e-105 351.2 3.6 6.8e-105 351.0 3.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Methyltransf_16 PF10294.9 KIY62725.1 - 1.4e-30 106.3 0.0 2e-30 105.8 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 KIY62725.1 - 0.00047 20.0 0.0 0.00075 19.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIY62725.1 - 0.028 15.2 0.0 0.047 14.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 KIY62725.1 - 0.067 13.9 0.0 0.14 12.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain WD40 PF00400.32 KIY62726.1 - 1.8e-26 91.8 12.2 0.00027 21.7 0.0 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.7 KIY62726.1 - 3.9e-14 52.2 1.5 7.1e-14 51.4 1.5 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY62726.1 - 4.5e-09 36.0 0.2 8.4e-09 35.1 0.2 1.4 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.8 KIY62726.1 - 2.3e-06 26.6 2.4 0.49 9.0 0.0 4.4 2 2 3 5 5 5 3 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KIY62726.1 - 1.7e-05 25.0 0.2 0.2 12.0 0.1 3.7 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KIY62726.1 - 0.00012 21.5 0.1 0.002 17.5 0.0 2.5 2 1 0 3 3 3 1 WD40-like domain F-box_5 PF18511.1 KIY62726.1 - 0.028 14.0 1.1 0.048 13.2 0.3 1.8 2 0 0 2 2 2 0 F-box DUF4644 PF15486.6 KIY62727.1 - 0.33 10.7 6.2 0.51 10.1 5.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4644) Ndc1_Nup PF09531.10 KIY62727.1 - 9.2 4.8 10.0 12 4.5 10.0 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup F-box-like PF12937.7 KIY62728.1 - 0.00028 20.7 0.4 0.00028 20.7 0.4 2.7 2 1 1 3 3 3 1 F-box-like F-box PF00646.33 KIY62728.1 - 0.00073 19.3 1.3 0.00073 19.3 1.3 1.9 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KIY62729.1 - 1.6e-10 40.7 0.2 4.5e-09 36.1 0.1 3.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIY62729.1 - 2.3 8.2 6.9 5.5 7.0 0.4 3.0 3 0 0 3 3 3 0 F-box domain SLD5_C PF16922.5 KIY62730.1 - 6.1e-06 26.3 0.0 1.2e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 KIY62730.1 - 0.00011 22.7 0.3 0.00016 22.1 0.3 1.5 1 0 0 1 1 1 1 GINS complex protein HbrB PF08539.11 KIY62730.1 - 0.029 14.3 0.4 0.046 13.7 0.4 1.3 1 0 0 1 1 1 0 HbrB-like CHAT PF12770.7 KIY62731.1 - 4.3e-30 105.1 0.1 7.9e-30 104.3 0.1 1.5 1 0 0 1 1 1 1 CHAT domain TPR_10 PF13374.6 KIY62731.1 - 8.4e-11 41.4 5.9 0.23 11.4 0.0 7.6 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_12 PF13424.6 KIY62731.1 - 0.0098 16.2 9.3 1 9.7 0.3 6.4 6 2 3 9 9 9 2 Tetratricopeptide repeat Adap_comp_sub PF00928.21 KIY62732.1 - 2.2e-22 79.7 0.0 3.6e-22 79.0 0.0 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KIY62732.1 - 2.1e-06 27.7 0.0 3.4e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain CopC PF04234.12 KIY62732.1 - 0.0056 17.7 0.2 3.3 8.8 0.0 3.2 3 0 0 3 3 3 1 CopC domain Phytoreo_Pns PF05451.11 KIY62732.1 - 0.04 13.1 0.0 0.062 12.4 0.0 1.2 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns10/11 DUF4337 PF14235.6 KIY62732.1 - 0.25 11.4 2.6 0.44 10.6 2.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) BTB PF00651.31 KIY62733.1 - 7.4e-11 42.3 0.0 3.9e-10 39.9 0.0 2.3 1 1 0 1 1 1 1 BTB/POZ domain HATPase_c_3 PF13589.6 KIY62733.1 - 0.0013 18.6 0.4 2.3 8.1 0.0 3.0 2 2 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase F-box PF00646.33 KIY62734.1 - 2.2e-08 33.7 0.5 3.1e-08 33.3 0.5 1.2 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KIY62734.1 - 0.00015 21.6 0.1 0.00025 20.9 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KIY62734.1 - 0.073 13.0 0.3 0.11 12.4 0.3 1.3 1 1 0 1 1 1 0 F-box SAE2 PF08573.10 KIY62735.1 - 2.4e-14 54.4 5.5 2.4e-14 54.4 5.5 3.9 2 2 1 3 3 3 1 DNA repair protein endonuclease SAE2/CtIP C-terminus ZapB PF06005.12 KIY62735.1 - 0.013 15.9 3.2 0.013 15.9 3.2 3.0 3 1 1 4 4 4 0 Cell division protein ZapB HALZ PF02183.18 KIY62735.1 - 8.7 6.7 13.8 27 5.1 0.3 3.8 3 1 1 4 4 4 0 Homeobox associated leucine zipper NARP1 PF12569.8 KIY62737.1 - 0.089 11.7 3.1 0.11 11.4 3.1 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Urb2 PF10441.9 KIY62739.1 - 0.063 13.2 0.0 0.094 12.6 0.0 1.2 1 0 0 1 1 1 0 Urb2/Npa2 family DUF4218 PF13960.6 KIY62740.1 - 0.0044 16.6 0.0 0.0065 16.1 0.0 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4218) Peptidase_M28 PF04389.17 KIY62743.1 - 1.9e-26 93.0 0.0 3e-26 92.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KIY62743.1 - 1.1e-05 25.3 0.0 1.7e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 KIY62743.1 - 0.012 14.7 0.1 1.4 7.9 0.0 2.2 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase Peptidase_M28 PF04389.17 KIY62744.1 - 2.2e-31 109.1 0.0 3.8e-31 108.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KIY62744.1 - 7.3e-06 25.8 0.0 1.3e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 KIY62744.1 - 0.041 12.9 0.0 3.5 6.6 0.0 2.2 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase MKT1_C PF12246.8 KIY62747.1 - 5.2e-68 228.9 0.0 5.4e-67 225.5 0.0 2.0 2 0 0 2 2 2 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.8 KIY62747.1 - 1.4e-26 92.7 0.0 2.9e-26 91.6 0.0 1.6 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.17 KIY62747.1 - 2.2e-07 31.3 0.0 6.6e-07 29.8 0.0 1.8 2 0 0 2 2 2 1 XPG N-terminal domain Mur_ligase_C PF02875.21 KIY62747.1 - 0.042 14.1 0.1 0.1 12.8 0.1 1.6 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain DUF4406 PF14359.6 KIY62749.1 - 0.21 12.1 0.0 0.68 10.5 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4406) F-box-like PF12937.7 KIY62750.1 - 3.5e-09 36.4 0.6 4.5e-09 36.1 0.6 1.2 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY62750.1 - 0.051 13.5 0.3 5.1 7.1 0.1 2.3 2 0 0 2 2 2 0 F-box domain p450 PF00067.22 KIY62751.1 - 4.5e-68 230.1 0.0 1.1e-67 228.9 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Peptidase_M43 PF05572.13 KIY62753.1 - 2.8e-19 69.5 0.1 4.5e-19 68.9 0.1 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 KIY62753.1 - 4.3e-08 33.5 0.1 6.5e-08 33.0 0.1 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 KIY62753.1 - 1.1e-07 32.3 0.0 2.1e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KIY62753.1 - 0.0002 21.1 0.6 0.00044 19.9 0.6 1.8 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KIY62753.1 - 0.0011 18.9 0.1 0.0015 18.5 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M7 PF02031.16 KIY62753.1 - 0.059 13.5 0.3 0.12 12.4 0.3 1.6 1 0 0 1 1 1 0 Streptomyces extracellular neutral proteinase (M7) family Peptidase_M66 PF10462.9 KIY62753.1 - 0.067 12.1 1.2 0.12 11.3 1.2 1.3 1 0 0 1 1 1 0 Peptidase M66 HMGL-like PF00682.19 KIY62754.1 - 2.4e-79 266.6 0.2 3.5e-79 266.1 0.2 1.2 1 0 0 1 1 1 1 HMGL-like Turandot PF07240.11 KIY62754.1 - 0.11 12.5 0.1 0.34 10.9 0.0 1.9 2 0 0 2 2 2 0 Stress-inducible humoral factor Turandot FliG_N PF14842.6 KIY62754.1 - 0.15 12.6 0.3 0.3 11.6 0.3 1.5 1 0 0 1 1 1 0 FliG N-terminal domain Peptidase_M43 PF05572.13 KIY62755.1 - 1.5e-15 57.4 0.1 2.3e-15 56.8 0.1 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 KIY62755.1 - 1.8e-08 34.7 0.1 2.9e-08 34.1 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 KIY62755.1 - 1.2e-07 32.3 0.0 2.1e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KIY62755.1 - 0.00017 21.3 0.1 0.00033 20.4 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 KIY62755.1 - 0.0055 15.7 0.1 0.0092 15.0 0.1 1.4 1 0 0 1 1 1 1 Peptidase M66 MCM PF00493.23 KIY62755.1 - 0.14 11.3 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 MCM P-loop domain Reprolysin_2 PF13574.6 KIY62755.1 - 0.14 12.0 0.8 0.32 10.9 0.8 1.7 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Ion_trans_2 PF07885.16 KIY62756.1 - 1.3e-23 82.7 29.8 2e-13 50.1 9.6 3.5 3 0 0 3 3 3 2 Ion channel FAD_oxidored PF12831.7 KIY62757.1 - 0.00011 21.7 0.0 0.00028 20.4 0.0 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KIY62757.1 - 0.06 12.2 0.3 1.1 8.0 0.0 2.7 3 0 0 3 3 3 0 Tryptophan halogenase Abhydrolase_6 PF12697.7 KIY62757.1 - 0.13 12.9 0.1 0.33 11.5 0.1 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase family UPF0227 PF05728.12 KIY62757.1 - 0.22 11.5 0.0 0.43 10.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Glyco_transf_25 PF01755.17 KIY62758.1 - 7.1e-10 39.1 0.0 1.1e-05 25.4 0.0 2.1 2 0 0 2 2 2 2 Glycosyltransferase family 25 (LPS biosynthesis protein) Gelsolin PF00626.22 KIY62759.1 - 1.3e-33 114.7 0.0 2.6e-16 59.3 0.0 3.2 3 0 0 3 3 3 3 Gelsolin repeat PIRT PF15099.6 KIY62760.1 - 0.38 10.3 1.3 0.6 9.7 0.0 1.9 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family Defensin_beta PF00711.19 KIY62761.1 - 0.22 11.6 1.0 0.41 10.7 0.6 1.7 2 0 0 2 2 2 0 Beta defensin Zn_clus PF00172.18 KIY62765.1 - 0.0012 18.9 10.8 0.002 18.2 10.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 KIY62766.1 - 0.00098 19.2 5.3 0.0018 18.4 5.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CAP_N PF01213.19 KIY62768.1 - 0.0055 16.2 10.4 0.0086 15.6 9.3 1.8 2 0 0 2 2 2 1 Adenylate cyclase associated (CAP) N terminal Nop14 PF04147.12 KIY62768.1 - 0.032 12.5 16.8 0.059 11.6 16.8 1.4 1 0 0 1 1 1 0 Nop14-like family Mito_fiss_reg PF05308.11 KIY62768.1 - 0.033 14.3 5.6 0.079 13.0 5.6 1.8 1 0 0 1 1 1 0 Mitochondrial fission regulator MSA-2c PF12238.8 KIY62768.1 - 0.073 13.1 7.5 11 5.9 0.0 2.3 2 0 0 2 2 2 0 Merozoite surface antigen 2c SDA1 PF05285.12 KIY62768.1 - 0.49 9.8 24.1 0.0099 15.3 15.7 2.0 2 0 0 2 2 2 0 SDA1 PRIMA1 PF16101.5 KIY62768.1 - 1.9 8.5 9.1 4.1 7.5 9.1 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Zn_clus PF00172.18 KIY62768.1 - 4.2 7.6 9.0 13 6.0 1.7 2.4 1 1 1 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Pap_E4 PF02711.14 KIY62768.1 - 6.8 7.7 13.1 3.7 8.6 7.9 2.9 2 0 0 2 2 2 0 E4 protein Usp PF00582.26 KIY62773.1 - 0.032 14.7 0.0 6.2 7.3 0.0 2.3 2 0 0 2 2 2 0 Universal stress protein family Dickkopf_N PF04706.12 KIY62774.1 - 0.082 13.4 1.1 0.082 13.4 1.1 2.5 2 1 1 3 3 3 0 Dickkopf N-terminal cysteine-rich region CLP_protease PF00574.23 KIY62777.1 - 1.7e-11 44.3 0.0 2.1e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 Clp protease CLP_protease PF00574.23 KIY62778.1 - 2.4e-10 40.6 0.2 3.9e-10 39.9 0.2 1.3 1 1 0 1 1 1 1 Clp protease TPR_12 PF13424.6 KIY62779.1 - 1.6e-14 54.0 2.6 7.6e-07 29.3 0.1 4.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KIY62779.1 - 1.5e-12 47.9 0.2 0.001 19.5 0.1 4.0 3 0 0 3 3 3 3 Tetratricopeptide repeat Paf67 PF10255.9 KIY62779.1 - 5.9e-07 28.8 0.6 9.1e-06 24.9 0.3 2.3 2 0 0 2 2 2 1 RNA polymerase I-associated factor PAF67 NB-ARC PF00931.22 KIY62779.1 - 4.3e-05 22.8 0.0 0.00021 20.6 0.0 2.0 1 1 0 1 1 1 1 NB-ARC domain TPR_2 PF07719.17 KIY62779.1 - 0.0001 22.1 0.2 5 7.5 0.1 5.1 4 1 0 4 4 4 1 Tetratricopeptide repeat NACHT PF05729.12 KIY62779.1 - 0.00013 22.0 0.0 0.00042 20.3 0.0 1.9 2 0 0 2 2 2 1 NACHT domain TPR_16 PF13432.6 KIY62779.1 - 0.00016 22.2 0.0 0.85 10.3 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KIY62779.1 - 0.00036 20.7 0.8 0.26 11.5 0.0 3.4 1 1 2 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 KIY62779.1 - 0.00054 20.6 0.1 30 5.8 0.0 5.3 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 KIY62779.1 - 0.00076 19.3 3.3 2.3 8.2 0.0 5.4 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 KIY62779.1 - 0.00091 19.7 0.6 4.6 8.1 0.1 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat CbiA PF01656.23 KIY62779.1 - 0.0024 18.0 0.0 0.0052 16.8 0.0 1.7 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain TPR_7 PF13176.6 KIY62779.1 - 0.0067 16.4 0.1 21 5.4 0.0 4.7 4 1 1 5 5 5 0 Tetratricopeptide repeat AAA_31 PF13614.6 KIY62779.1 - 0.0073 16.2 0.0 0.017 15.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KIY62779.1 - 0.029 14.7 0.0 0.084 13.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain TPR_20 PF14561.6 KIY62779.1 - 0.038 14.3 0.2 3.7 8.0 0.0 3.6 1 1 1 3 3 3 0 Tetratricopeptide repeat PhoH PF02562.16 KIY62779.1 - 0.041 13.3 0.2 0.1 12.1 0.2 1.6 1 0 0 1 1 1 0 PhoH-like protein RecA PF00154.21 KIY62779.1 - 0.045 13.2 0.0 0.078 12.4 0.0 1.3 1 0 0 1 1 1 0 recA bacterial DNA recombination protein AAA_16 PF13191.6 KIY62779.1 - 0.098 13.0 1.5 0.82 10.0 1.5 2.3 1 1 0 1 1 1 0 AAA ATPase domain ATPase_2 PF01637.18 KIY62779.1 - 0.11 12.4 0.0 0.28 11.1 0.0 1.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_14 PF13173.6 KIY62779.1 - 0.15 12.1 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KIY62780.1 - 3.4e-10 39.5 0.0 5.6e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain NACHT PF05729.12 KIY62780.1 - 0.00089 19.2 0.8 0.0027 17.6 0.2 2.1 2 1 0 2 2 2 1 NACHT domain CbiA PF01656.23 KIY62780.1 - 0.0059 16.7 0.0 0.012 15.7 0.0 1.6 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.6 KIY62780.1 - 0.0062 16.8 0.0 0.02 15.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KIY62780.1 - 0.043 13.5 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KIY62780.1 - 0.051 14.1 0.0 0.092 13.3 0.0 1.4 1 0 0 1 1 1 0 ABC transporter ATPase_2 PF01637.18 KIY62780.1 - 0.055 13.4 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_33 PF13671.6 KIY62780.1 - 0.063 13.4 0.0 0.16 12.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KIY62780.1 - 0.078 12.7 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KIY62780.1 - 0.11 12.8 6.1 2.8 8.3 3.6 3.2 2 1 0 2 2 2 0 AAA ATPase domain DNA_topoisoIV PF00521.20 KIY62781.1 - 2.8e-126 421.9 0.1 5.2e-126 421.0 0.1 1.5 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 KIY62781.1 - 1.3e-51 174.1 1.6 1.3e-51 174.1 1.6 2.1 2 0 0 2 2 2 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 KIY62781.1 - 7.8e-25 87.3 0.2 2e-24 86.0 0.2 1.7 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 KIY62781.1 - 7.7e-12 45.7 0.0 2.3e-11 44.2 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 KIY62781.1 - 7.9e-08 32.5 0.0 4.8e-07 29.9 0.0 2.4 2 0 0 2 2 2 1 Toprim domain Glyco_trans_1_4 PF13692.6 KIY62782.1 - 1.3e-07 32.1 0.0 2.3e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KIY62782.1 - 2.6e-06 28.0 0.0 5.7e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glycos_transf_1 PF00534.20 KIY62782.1 - 1.2e-05 25.0 0.0 1.9e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KIY62782.1 - 2.2e-05 24.5 0.1 5.2e-05 23.3 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 KIY62782.1 - 9.4e-05 22.7 0.0 0.00017 21.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Ribosomal_L28 PF00830.19 KIY62783.1 - 2.9e-20 72.2 0.6 2.9e-20 72.2 0.6 1.7 2 0 0 2 2 2 1 Ribosomal L28 family SBP_bac_1 PF01547.25 KIY62784.1 - 0.078 12.9 0.4 0.1 12.5 0.4 1.1 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein 4F5 PF04419.14 KIY62785.1 - 0.00013 22.8 14.0 0.00013 22.8 14.0 2.3 2 0 0 2 2 2 1 4F5 protein family Bac_surface_Ag PF01103.23 KIY62787.1 - 1.8e-38 132.8 0.3 2.2e-38 132.6 0.3 1.1 1 0 0 1 1 1 1 Surface antigen Fungal_trans PF04082.18 KIY62788.1 - 4e-20 72.0 0.0 9e-20 70.8 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY62788.1 - 5.3e-07 29.7 9.9 9.6e-07 28.8 9.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.13 KIY62788.1 - 0.012 15.7 0.0 0.042 14.0 0.0 1.9 1 0 0 1 1 1 0 Gal4-like dimerisation domain Fungal_trans PF04082.18 KIY62789.1 - 2.9e-20 72.4 0.0 4.6e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY62789.1 - 1.6e-07 31.4 10.6 3e-07 30.5 10.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.13 KIY62789.1 - 0.088 13.0 0.1 0.17 12.0 0.1 1.5 1 0 0 1 1 1 0 Gal4-like dimerisation domain PAR1 PF06521.11 KIY62791.1 - 0.027 14.1 4.6 0.078 12.6 0.2 2.9 1 1 2 3 3 3 0 PAR1 protein GTP-bdg_N PF13167.6 KIY62791.1 - 0.17 12.6 0.9 0.98 10.1 0.0 2.6 3 1 1 4 4 4 0 GTP-binding GTPase N-terminal FliD_N PF02465.18 KIY62791.1 - 3.6 8.4 8.2 24 5.7 0.1 2.9 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus EI24 PF07264.11 KIY62793.1 - 0.14 12.4 8.9 0.23 11.7 8.9 1.3 1 0 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) DUF4199 PF13858.6 KIY62793.1 - 0.5 10.8 5.7 0.92 9.9 5.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Ribosomal_L6 PF00347.23 KIY62794.1 - 4.8e-19 68.8 0.0 2.9e-08 34.3 0.0 2.5 2 1 0 2 2 2 2 Ribosomal protein L6 ATP-synt_C PF00137.21 KIY62795.1 - 6.1e-32 109.8 31.9 3.4e-19 68.9 10.9 2.1 2 0 0 2 2 2 2 ATP synthase subunit C PAR1 PF06521.11 KIY62796.1 - 0.054 13.1 0.2 0.054 13.1 0.2 2.6 1 1 2 3 3 3 0 PAR1 protein FliD_N PF02465.18 KIY62796.1 - 1 10.1 6.9 8 7.2 0.1 2.6 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Ifi-6-16 PF06140.13 KIY62798.1 - 0.032 14.1 7.6 0.073 13.0 2.3 2.2 1 1 1 2 2 2 0 Interferon-induced 6-16 family ApoL PF05461.11 KIY62798.1 - 3.9 6.7 4.3 4.2 6.6 4.3 1.0 1 0 0 1 1 1 0 Apolipoprotein L bZIP_2 PF07716.15 KIY62799.1 - 1.2e-06 28.5 5.7 1.2e-06 28.5 5.7 1.9 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 KIY62799.1 - 6.5e-05 22.9 6.7 0.00012 22.1 6.7 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 KIY62799.1 - 0.00022 21.7 2.8 0.00022 21.7 2.8 1.7 2 0 0 2 2 2 1 bZIP Maf transcription factor HMG_box PF00505.19 KIY62800.1 - 5e-09 36.5 0.0 1.4e-08 35.1 0.0 1.8 1 0 0 1 1 1 1 HMG (high mobility group) box F-box-like PF12937.7 KIY62805.1 - 0.00037 20.3 0.4 0.00037 20.3 0.4 2.6 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 KIY62805.1 - 0.11 12.4 0.3 0.3 11.0 0.3 1.7 1 0 0 1 1 1 0 F-box domain Ifi-6-16 PF06140.13 KIY62806.1 - 2.1e-08 34.0 15.9 4e-08 33.1 15.9 1.5 1 1 0 1 1 1 1 Interferon-induced 6-16 family F-box PF00646.33 KIY62809.1 - 0.00075 19.3 1.3 0.25 11.3 0.2 2.7 2 0 0 2 2 2 2 F-box domain F-box-like PF12937.7 KIY62809.1 - 0.0015 18.4 4.1 0.61 10.0 0.4 3.2 3 0 0 3 3 3 2 F-box-like DUF1699 PF08004.11 KIY62809.1 - 0.062 13.0 0.1 8.1 6.1 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1699) Act-Frag_cataly PF09192.10 KIY62809.1 - 0.19 11.0 0.0 0.3 10.4 0.0 1.2 1 0 0 1 1 1 0 Actin-fragmin kinase, catalytic LRR_4 PF12799.7 KIY62809.1 - 4.6 7.8 5.6 1.1e+02 3.4 0.1 4.2 3 2 2 5 5 5 0 Leucine Rich repeats (2 copies) Rad4 PF03835.15 KIY62810.1 - 1e-19 70.7 0.0 1.8e-19 69.9 0.0 1.5 1 1 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.19 KIY62810.1 - 6.2e-06 26.6 0.0 1.7e-05 25.2 0.0 1.7 1 1 0 1 1 1 1 Transglutaminase-like superfamily zf-MYND PF01753.18 KIY62813.1 - 3.1e-11 43.2 7.0 8.5e-11 41.8 7.0 1.7 1 0 0 1 1 1 1 MYND finger Ank_2 PF12796.7 KIY62813.1 - 0.00039 20.9 0.0 1.3 9.7 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KIY62813.1 - 0.0043 17.4 0.0 3.2 8.4 0.0 3.5 4 1 0 4 4 4 1 Ankyrin repeat Ank_3 PF13606.6 KIY62813.1 - 0.031 14.8 0.2 11 7.0 0.0 4.2 4 0 0 4 4 4 0 Ankyrin repeat zf-C6H2 PF15801.5 KIY62813.1 - 0.32 11.3 7.3 0.7 10.2 7.3 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding SEC-C PF02810.15 KIY62813.1 - 0.71 9.9 19.9 0.53 10.3 4.1 2.5 2 0 0 2 2 2 0 SEC-C motif zf-MYND PF01753.18 KIY62814.1 - 1.8e-09 37.5 12.9 3.8e-09 36.5 12.9 1.6 1 0 0 1 1 1 1 MYND finger Ank_5 PF13857.6 KIY62814.1 - 0.00016 21.9 0.1 0.092 13.1 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KIY62814.1 - 0.00019 22.0 0.0 0.11 13.2 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KIY62814.1 - 0.0002 21.5 0.9 0.15 12.7 0.0 4.0 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.30 KIY62814.1 - 0.0038 17.6 0.3 2.3 8.8 0.1 3.7 2 1 0 2 2 2 1 Ankyrin repeat SEC-C PF02810.15 KIY62814.1 - 0.0068 16.3 2.4 0.0068 16.3 2.4 2.5 2 0 0 2 2 2 1 SEC-C motif zf-C6H2 PF15801.5 KIY62814.1 - 1.2 9.5 11.4 2.6 8.4 11.4 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding VWA_2 PF13519.6 KIY62815.1 - 1.8e-11 44.6 0.0 5.6e-11 43.0 0.0 1.9 1 0 0 1 1 1 1 von Willebrand factor type A domain RHD3 PF05879.12 KIY62815.1 - 2.6e-06 25.9 0.1 3.9e-06 25.3 0.1 1.3 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) VWA_CoxE PF05762.14 KIY62815.1 - 2.9e-06 26.8 2.4 2.2e-05 24.0 0.7 3.0 3 0 0 3 3 3 1 VWA domain containing CoxE-like protein VWA PF00092.28 KIY62815.1 - 1.8e-05 25.0 0.0 0.00011 22.6 0.0 2.1 1 1 0 1 1 1 1 von Willebrand factor type A domain GBP PF02263.19 KIY62815.1 - 6.2e-05 22.4 0.0 0.00012 21.5 0.0 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain MucB_RseB_C PF17188.4 KIY62815.1 - 0.13 12.5 0.0 0.4 10.9 0.0 1.8 1 0 0 1 1 1 0 MucB/RseB C-terminal domain IBR PF01485.21 KIY62816.1 - 6.2e-07 29.5 6.9 6.2e-07 29.5 6.9 3.9 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 KIY62816.1 - 0.0009 19.5 9.2 0.0009 19.5 9.2 4.1 3 1 0 3 3 3 1 Ring finger domain ZapB PF06005.12 KIY62816.1 - 0.0019 18.6 0.7 0.0019 18.6 0.7 2.5 3 0 0 3 3 2 1 Cell division protein ZapB zf-C3HC4 PF00097.25 KIY62816.1 - 0.0026 17.6 9.9 0.0026 17.6 9.9 4.5 3 2 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) CASP_C PF08172.12 KIY62816.1 - 0.0033 16.8 1.9 0.0048 16.3 1.9 1.3 1 0 0 1 1 1 1 CASP C terminal DUF4472 PF14739.6 KIY62816.1 - 0.0036 18.0 2.0 0.0036 18.0 2.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4472) zf-RING_UBOX PF13445.6 KIY62816.1 - 0.0051 16.8 7.5 0.0051 16.8 7.5 3.7 3 0 0 3 3 3 1 RING-type zinc-finger LCD1 PF09798.9 KIY62816.1 - 0.009 14.6 0.8 0.012 14.1 0.8 1.1 1 0 0 1 1 1 1 DNA damage checkpoint protein zf-RING_5 PF14634.6 KIY62816.1 - 0.021 14.8 7.8 0.021 14.8 7.8 3.9 2 1 1 3 3 2 0 zinc-RING finger domain YabA PF06156.13 KIY62816.1 - 0.025 15.2 1.0 0.074 13.7 1.0 1.8 1 0 0 1 1 1 0 Initiation control protein YabA Fez1 PF06818.15 KIY62816.1 - 0.095 13.1 6.4 0.16 12.4 6.4 1.3 1 0 0 1 1 1 0 Fez1 NUDE_C PF04880.13 KIY62816.1 - 0.12 12.9 11.3 0.22 12.0 11.3 1.4 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region zf-TFIIB PF13453.6 KIY62816.1 - 0.19 11.1 8.3 0.35 10.3 0.0 3.7 3 0 0 3 3 3 0 Transcription factor zinc-finger bZIP_1 PF00170.21 KIY62816.1 - 0.2 11.8 4.7 0.45 10.7 4.7 1.5 1 0 0 1 1 1 0 bZIP transcription factor Spc24 PF08286.11 KIY62816.1 - 0.3 11.4 1.9 0.76 10.0 1.9 1.7 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 ADIP PF11559.8 KIY62816.1 - 0.8 9.8 8.2 0.61 10.2 6.3 1.7 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF724 PF05266.14 KIY62816.1 - 1.1 9.0 6.4 1.1 9.1 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Cys_rich_KTR PF14205.6 KIY62816.1 - 9.9 6.0 9.9 7.3 6.5 1.2 3.4 3 0 0 3 3 3 0 Cysteine-rich KTR UPF0016 PF01169.19 KIY62817.1 - 6.2e-44 148.2 20.9 1.2e-22 80.0 8.3 2.1 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 Mntp PF02659.15 KIY62817.1 - 0.00093 19.0 0.6 0.00093 19.0 0.6 2.3 2 0 0 2 2 2 1 Putative manganese efflux pump TerC PF03741.16 KIY62817.1 - 0.0011 18.7 4.3 0.0038 16.9 0.1 2.3 2 0 0 2 2 2 1 Integral membrane protein TerC family Cad PF03596.13 KIY62817.1 - 0.0035 17.2 0.7 0.012 15.5 0.0 1.9 2 0 0 2 2 2 1 Cadmium resistance transporter Peptidase_U4 PF03419.13 KIY62817.1 - 0.057 12.7 0.1 0.057 12.7 0.1 2.0 2 0 0 2 2 2 0 Sporulation factor SpoIIGA MttA_Hcf106 PF02416.16 KIY62817.1 - 0.1 11.9 2.2 1.1 8.7 0.0 2.3 2 0 0 2 2 2 0 mttA/Hcf106 family LysE PF01810.18 KIY62817.1 - 0.46 9.9 16.1 1.3 8.4 3.7 2.9 3 0 0 3 3 3 0 LysE type translocator EamA PF00892.20 KIY62820.1 - 1.8e-19 70.3 30.4 2.5e-11 43.9 12.9 2.2 2 0 0 2 2 2 2 EamA-like transporter family DUF2070 PF09843.9 KIY62820.1 - 6.6 4.9 18.1 3.7 5.7 2.9 2.0 1 1 0 2 2 2 0 Predicted membrane protein (DUF2070) DUF3433 PF11915.8 KIY62821.1 - 2.4e-16 59.9 8.1 2.4e-16 59.9 8.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3433) Sec20 PF03908.13 KIY62822.1 - 0.24 11.3 0.7 0.77 9.7 0.1 2.2 2 0 0 2 2 2 0 Sec20 Hydrophobin PF01185.18 KIY62823.1 - 9.3e-13 48.6 8.0 1.2e-12 48.3 8.0 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Cys_Knot_tox PF17486.2 KIY62823.1 - 0.075 13.3 4.7 2.8 8.2 0.5 2.1 2 0 0 2 2 2 0 Cystine knot toxins Tubulin PF00091.25 KIY62824.1 - 6.3e-68 228.9 0.0 1.3e-67 227.8 0.0 1.5 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KIY62824.1 - 4.5e-43 146.4 0.2 7.1e-43 145.8 0.2 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KIY62824.1 - 8.2e-06 26.1 0.0 3e-05 24.3 0.0 2.0 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 KIY62824.1 - 0.00071 18.9 0.0 0.01 15.1 0.0 2.1 2 0 0 2 2 2 1 Tubulin like Tubulin_3 PF14881.6 KIY62824.1 - 0.0095 15.6 0.0 0.021 14.5 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain TrmK PF04816.12 KIY62824.1 - 0.1 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 tRNA (adenine(22)-N(1))-methyltransferase Maf1 PF09174.10 KIY62826.1 - 5.7e-34 117.8 0.0 9.1e-26 91.1 0.0 2.6 2 1 0 2 2 2 2 Maf1 regulator Polysacc_deac_1 PF01522.21 KIY62827.1 - 1.8e-32 111.9 0.7 4.2e-32 110.7 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide deacetylase TPR_2 PF07719.17 KIY62828.1 - 2e-12 46.2 0.8 0.0017 18.3 0.0 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 KIY62828.1 - 2.7e-09 36.5 0.1 0.0026 17.5 0.0 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 KIY62828.1 - 5e-08 33.1 7.3 0.0057 16.9 0.2 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 KIY62828.1 - 8.7e-07 29.5 1.1 1.6 9.5 0.0 5.1 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 KIY62828.1 - 3e-06 27.6 0.7 4.7 7.8 0.0 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 KIY62828.1 - 8.9e-06 25.3 0.1 0.11 12.2 0.0 3.9 4 0 0 4 4 4 2 TPR repeat TPR_17 PF13431.6 KIY62828.1 - 1e-05 25.5 0.1 0.0065 16.8 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 KIY62828.1 - 1.6e-05 24.9 0.1 0.0028 17.8 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 KIY62828.1 - 2.4e-05 24.2 0.0 3.2 8.2 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KIY62828.1 - 2.5e-05 24.7 6.9 0.82 10.7 0.0 6.6 6 1 1 7 7 7 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KIY62828.1 - 0.014 15.6 0.0 0.22 11.8 0.0 3.0 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 KIY62828.1 - 0.019 15.0 2.8 4.6 7.5 0.0 5.6 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 KIY62828.1 - 0.023 14.6 9.5 0.25 11.2 0.0 4.7 5 1 0 5 5 5 0 Tetratricopeptide repeat MFS_1 PF07690.16 KIY62829.1 - 5.6e-41 140.6 52.9 3e-29 102.1 18.9 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KIY62829.1 - 1.2e-10 40.8 25.1 2.7e-06 26.5 0.5 4.1 2 2 2 4 4 4 3 MFS_1 like family MFS_2 PF13347.6 KIY62829.1 - 6.1e-06 25.0 30.4 0.00016 20.3 11.6 3.1 2 1 1 3 3 3 3 MFS/sugar transport protein OATP PF03137.20 KIY62829.1 - 8.4e-05 21.0 0.8 8.4e-05 21.0 0.8 3.3 3 1 1 4 4 4 2 Organic Anion Transporter Polypeptide (OATP) family DUF1218 PF06749.12 KIY62829.1 - 0.72 10.4 6.1 1.8 9.1 0.4 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1218) zf-C3HC4_2 PF13923.6 KIY62830.1 - 4.1e-08 32.9 9.5 4.1e-08 32.9 9.5 3.4 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIY62830.1 - 9.4e-07 29.1 9.2 9.4e-07 29.1 9.2 4.1 2 1 3 5 5 4 1 Ring finger domain zf-Nse PF11789.8 KIY62830.1 - 2.8e-06 27.0 4.9 2.8e-06 27.0 4.9 3.2 3 0 0 3 3 3 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 KIY62830.1 - 2.8e-06 27.2 11.1 2.8e-06 27.2 11.1 3.1 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KIY62830.1 - 8.4e-06 25.6 9.4 8.4e-06 25.6 9.4 3.5 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-TRAF PF02176.18 KIY62830.1 - 7.7e-05 23.3 35.1 0.00043 20.9 8.6 4.2 2 1 3 5 5 5 4 TRAF-type zinc finger zf-RING_5 PF14634.6 KIY62830.1 - 0.00068 19.5 8.1 0.00068 19.5 8.1 3.6 3 1 0 3 3 3 1 zinc-RING finger domain zf-rbx1 PF12678.7 KIY62830.1 - 0.0026 18.0 7.1 0.0026 18.0 7.1 3.9 2 2 2 4 4 4 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 KIY62830.1 - 0.0028 17.5 6.7 0.0028 17.5 6.7 3.9 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-TRAF_2 PF15965.5 KIY62830.1 - 0.0059 17.0 9.8 0.0059 17.0 9.8 3.4 2 1 1 3 3 3 1 TRAF-like zinc-finger zf-C3HC4_4 PF15227.6 KIY62830.1 - 0.0085 16.2 9.3 0.0085 16.2 9.3 3.4 2 1 1 3 3 3 1 zinc finger of C3HC4-type, RING DM PF00751.18 KIY62830.1 - 0.026 14.4 2.9 0.026 14.4 2.9 3.8 3 0 0 3 3 3 0 DM DNA binding domain DUF1640 PF07798.11 KIY62830.1 - 0.15 12.1 0.2 3 7.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) zf-RING_6 PF14835.6 KIY62830.1 - 4.6 7.2 17.0 0.029 14.2 4.0 2.8 2 1 0 2 2 2 0 zf-RING of BARD1-type protein DEAD PF00270.29 KIY62831.1 - 7.8e-48 162.5 0.0 1.2e-47 161.9 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIY62831.1 - 1.6e-31 108.9 0.0 4.2e-31 107.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIY62831.1 - 2.5e-05 24.3 0.0 6.3e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KIY62831.1 - 0.00022 20.5 0.2 0.00044 19.5 0.1 1.5 1 1 1 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase DUF3636 PF12331.8 KIY62832.1 - 0.13 12.0 0.6 0.24 11.2 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3636) TRAPPC10 PF12584.8 KIY62833.1 - 8.9e-35 119.7 0.0 2e-34 118.6 0.0 1.6 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 HtaA PF04213.13 KIY62833.1 - 0.043 14.3 0.0 0.14 12.6 0.0 1.9 1 0 0 1 1 1 0 Htaa BAG PF02179.16 KIY62834.1 - 2e-18 66.6 0.0 2.9e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.23 KIY62834.1 - 1e-07 31.6 0.0 1.9e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family PAXNEB PF05625.11 KIY62834.1 - 0.043 12.9 0.0 0.052 12.7 0.0 1.1 1 0 0 1 1 1 0 PAXNEB protein Rad60-SLD PF11976.8 KIY62834.1 - 0.067 13.0 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Pkinase PF00069.25 KIY62835.1 - 6.5e-55 186.3 0.0 7.9e-55 186.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY62835.1 - 1.1e-37 129.7 0.0 1.5e-37 129.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY62835.1 - 4.1e-07 29.6 0.0 5.8e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KIY62835.1 - 0.0028 16.5 0.0 0.0085 14.9 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 KIY62835.1 - 0.022 13.7 0.0 0.032 13.2 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain CCDC14 PF15254.6 KIY62836.1 - 0.0065 15.2 2.9 0.0075 15.0 2.9 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 14 DUF4611 PF15387.6 KIY62836.1 - 1.3 9.3 13.9 2.9 8.2 1.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) Tau95_N PF17682.1 KIY62836.1 - 1.5 9.0 6.4 0.18 12.0 0.3 2.3 2 0 0 2 2 2 0 Tau95 Triple barrel domain TLP-20 PF06088.11 KIY62836.1 - 3.8 7.4 9.8 2.5 8.0 1.6 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Ribosomal_L13 PF00572.18 KIY62837.1 - 1.3e-49 167.6 0.0 1.6e-49 167.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 Aldo_ket_red PF00248.21 KIY62838.1 - 5.3e-49 167.0 0.1 8.4e-47 159.8 0.1 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Asp PF00026.23 KIY62840.1 - 4.5e-51 174.1 11.0 9.9e-51 173.0 11.0 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIY62840.1 - 1.3e-07 32.1 4.3 2.8e-05 24.4 0.1 3.2 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KIY62840.1 - 8.4e-05 23.1 4.1 0.0051 17.4 0.7 2.5 2 0 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.6 KIY62840.1 - 0.067 13.0 0.2 8.9 6.1 0.0 2.3 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 KIY62840.1 - 0.094 13.3 2.2 0.81 10.3 0.1 2.6 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease Asp PF00026.23 KIY62841.1 - 4.5e-46 157.7 1.7 2.1e-45 155.5 1.7 1.8 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIY62841.1 - 3.7e-08 33.8 0.2 6.4e-05 23.3 0.1 3.2 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KIY62841.1 - 0.0018 18.9 1.3 0.18 12.4 0.2 2.6 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 KIY62841.1 - 0.02 15.4 0.5 0.31 11.6 0.0 2.4 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Egh16-like PF11327.8 KIY62842.1 - 4.5e-41 141.3 5.3 4.5e-41 141.3 5.3 3.0 1 1 2 3 3 3 1 Egh16-like virulence factor mRNA_triPase PF02940.15 KIY62843.1 - 1.4e-47 162.2 0.0 1.7e-47 161.9 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain MFS_1 PF07690.16 KIY62844.1 - 3.2e-25 88.8 32.7 4.9e-25 88.2 32.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily BT1 PF03092.16 KIY62844.1 - 0.21 9.8 4.7 0.19 9.9 0.4 2.1 2 0 0 2 2 2 0 BT1 family DUF3792 PF12670.7 KIY62844.1 - 0.91 9.7 10.5 0.71 10.1 0.8 3.2 2 2 1 3 3 3 0 Protein of unknown function (DUF3792) ABC_membrane PF00664.23 KIY62845.1 - 4e-100 335.0 25.5 2e-50 172.0 3.6 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KIY62845.1 - 1.4e-68 229.7 0.0 1.4e-33 116.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KIY62845.1 - 2.1e-13 50.3 0.0 2.4e-05 23.9 0.0 3.9 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KIY62845.1 - 8e-08 32.8 1.0 0.001 19.5 0.1 3.3 3 0 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 KIY62845.1 - 8.9e-07 29.3 0.5 0.056 13.7 0.1 4.4 3 2 0 3 3 3 2 AAA domain AAA_29 PF13555.6 KIY62845.1 - 3.1e-06 26.8 0.4 0.084 12.6 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.9 KIY62845.1 - 6.2e-06 25.3 0.0 0.0028 16.5 0.0 2.4 2 0 0 2 2 2 2 Predicted ATPase of the ABC class Zeta_toxin PF06414.12 KIY62845.1 - 4.1e-05 23.0 0.5 0.035 13.4 0.0 2.9 3 0 0 3 3 3 2 Zeta toxin G-alpha PF00503.20 KIY62845.1 - 8.7e-05 21.8 0.0 0.15 11.2 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit DUF87 PF01935.17 KIY62845.1 - 0.00011 22.4 0.1 0.45 10.6 0.0 2.5 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_30 PF13604.6 KIY62845.1 - 0.00013 21.8 0.8 0.77 9.5 0.2 3.0 2 1 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KIY62845.1 - 0.0002 21.3 0.0 0.27 11.1 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 KIY62845.1 - 0.00028 20.8 0.8 1.5 8.6 0.0 3.6 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 KIY62845.1 - 0.00059 20.0 0.0 1.7 8.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 KIY62845.1 - 0.00069 19.4 0.0 0.48 10.1 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain SbcCD_C PF13558.6 KIY62845.1 - 0.00086 19.5 3.2 0.4 10.9 0.6 3.6 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.14 KIY62845.1 - 0.0047 16.9 0.1 2.9 7.9 0.0 2.9 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KIY62845.1 - 0.0062 17.1 0.0 1.2 9.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KIY62845.1 - 0.0072 15.9 0.0 1.7 8.1 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 KIY62845.1 - 0.0085 15.5 0.1 1.2 8.4 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_28 PF13521.6 KIY62845.1 - 0.0086 16.3 2.3 1.1 9.5 0.0 3.4 4 0 0 4 4 3 1 AAA domain DUF815 PF05673.13 KIY62845.1 - 0.034 13.3 0.0 4.6 6.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_25 PF13481.6 KIY62845.1 - 0.034 13.7 2.3 5 6.7 0.0 3.7 4 0 0 4 4 4 0 AAA domain APS_kinase PF01583.20 KIY62845.1 - 0.035 14.0 0.1 6.8 6.6 0.0 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase PRK PF00485.18 KIY62845.1 - 0.067 12.9 0.0 12 5.5 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_24 PF13479.6 KIY62845.1 - 0.1 12.3 0.0 11 5.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KIY62845.1 - 0.12 12.4 0.1 18 5.5 0.0 3.0 3 0 0 3 3 2 0 50S ribosome-binding GTPase DUF3987 PF13148.6 KIY62845.1 - 0.14 11.1 0.1 1.8 7.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) ATP_bind_1 PF03029.17 KIY62845.1 - 0.17 11.6 0.1 22 4.7 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_23 PF13476.6 KIY62845.1 - 0.21 12.1 0.0 23 5.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain Rad60-SLD PF11976.8 KIY62846.1 - 1.5e-08 34.4 0.0 0.012 15.4 0.0 3.5 3 0 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KIY62846.1 - 0.044 13.5 0.0 40 4.0 0.0 3.4 3 0 0 3 3 3 0 Ubiquitin family RA PF00788.23 KIY62846.1 - 0.06 14.0 0.3 0.38 11.4 0.0 2.4 3 0 0 3 3 3 0 Ras association (RalGDS/AF-6) domain Pkinase_fungal PF17667.1 KIY62848.1 - 5.8e-11 41.8 1.3 0.00016 20.6 0.1 2.2 2 0 0 2 2 2 2 Fungal protein kinase RRM_1 PF00076.22 KIY62849.1 - 1.6e-29 101.5 4.3 5.5e-10 38.9 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KIY62849.1 - 9.3e-06 25.4 0.1 0.64 9.9 0.0 4.0 4 0 0 4 4 4 2 Occluded RNA-recognition motif RRM_3 PF08777.11 KIY62849.1 - 1.9e-05 24.6 0.2 0.075 13.1 0.1 2.7 2 0 0 2 2 2 2 RNA binding motif DUF1866 PF08952.11 KIY62849.1 - 2.2e-05 24.4 0.1 0.44 10.4 0.0 4.0 2 2 2 4 4 4 1 Domain of unknown function (DUF1866) RRM_5 PF13893.6 KIY62849.1 - 0.0017 17.9 0.0 0.51 9.9 0.0 3.2 2 1 1 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NID PF07292.13 KIY62849.1 - 0.0073 16.9 0.0 1.9 9.2 0.0 2.9 3 0 0 3 3 3 1 Nmi/IFP 35 domain (NID) RRM_7 PF16367.5 KIY62849.1 - 0.021 14.9 0.0 0.33 11.1 0.0 2.8 3 0 0 3 3 3 0 RNA recognition motif Nup35_RRM_2 PF14605.6 KIY62849.1 - 0.024 14.7 0.0 7.9 6.6 0.1 3.6 4 0 0 4 4 4 0 Nup53/35/40-type RNA recognition motif zf-MYND PF01753.18 KIY62850.1 - 1.2e-07 31.7 11.5 2.6e-07 30.6 11.5 1.6 1 0 0 1 1 1 1 MYND finger F-box-like PF12937.7 KIY62860.1 - 1.1e-05 25.2 2.1 0.00035 20.4 0.0 3.0 3 0 0 3 3 3 2 F-box-like zf-MYND PF01753.18 KIY62861.1 - 8.5e-09 35.4 11.4 1.6e-08 34.5 11.4 1.4 1 0 0 1 1 1 1 MYND finger MIOX PF05153.15 KIY62862.1 - 3.6e-123 410.0 2.2 4.3e-123 409.7 2.2 1.0 1 0 0 1 1 1 1 Myo-inositol oxygenase HD PF01966.22 KIY62862.1 - 0.00055 20.2 0.2 0.028 14.6 0.0 2.5 3 0 0 3 3 3 1 HD domain FA_hydroxylase PF04116.13 KIY62863.1 - 1.4e-23 83.7 17.6 1.4e-23 83.7 17.6 1.8 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily COX4 PF02936.14 KIY62865.1 - 0.063 13.3 0.0 0.088 12.8 0.0 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV SPX PF03105.19 KIY62865.1 - 0.92 9.4 7.7 1.1 9.0 7.7 1.1 1 0 0 1 1 1 0 SPX domain DUF956 PF06115.11 KIY62866.1 - 0.1 12.3 0.0 4.3 7.1 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF956) F-box-like PF12937.7 KIY62866.1 - 1.3 8.9 9.7 0.054 13.4 2.4 2.7 3 0 0 3 3 3 0 F-box-like TINF2_N PF14973.6 KIY62867.1 - 0.31 11.4 2.8 2.5 8.5 3.1 2.1 2 0 0 2 2 2 0 TERF1-interacting nuclear factor 2 N-terminus MgtE_N PF03448.17 KIY62868.1 - 0.11 13.1 0.0 0.27 11.9 0.0 1.6 1 0 0 1 1 1 0 MgtE intracellular N domain zf-C2H2 PF00096.26 KIY62869.1 - 0.79 10.3 7.8 0.3 11.6 5.0 1.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type F-box-like PF12937.7 KIY62870.1 - 5e-06 26.3 1.4 2.4e-05 24.1 1.4 2.3 1 1 0 1 1 1 1 F-box-like F-box-like PF12937.7 KIY62871.1 - 2.3e-08 33.8 0.1 1.2e-07 31.5 0.2 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIY62871.1 - 0.012 15.5 2.9 0.12 12.2 2.9 2.6 1 1 0 1 1 1 0 F-box domain UQ_con PF00179.26 KIY62875.1 - 2.5e-44 150.4 0.0 2.8e-44 150.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KIY62875.1 - 0.12 12.0 0.0 0.43 10.3 0.0 1.8 1 1 0 1 1 1 0 Prokaryotic E2 family B ALO PF04030.14 KIY62876.1 - 2.1e-77 260.4 0.1 2.7e-77 260.1 0.1 1.1 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 KIY62876.1 - 4.9e-28 97.6 0.3 8.2e-28 96.9 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain HSP70 PF00012.20 KIY62877.1 - 0.095 10.9 0.0 0.31 9.2 0.0 1.6 1 1 0 1 1 1 0 Hsp70 protein F-box-like PF12937.7 KIY62879.1 - 1.3e-05 25.0 0.2 1.5e-05 24.8 0.2 1.1 1 0 0 1 1 1 1 F-box-like COesterase PF00135.28 KIY62880.1 - 4.3e-91 306.3 0.0 2.3e-89 300.6 0.0 2.0 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 KIY62880.1 - 0.0035 16.8 0.1 0.0061 16.1 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 KIY62880.1 - 0.0076 16.1 0.2 0.018 14.9 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Got1 PF04178.12 KIY62882.1 - 6.9e-30 103.8 13.7 8.7e-30 103.5 13.7 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family DUF4728 PF15860.5 KIY62882.1 - 0.048 14.3 0.9 0.08 13.6 0.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4728) DUF2070 PF09843.9 KIY62882.1 - 0.59 8.4 5.9 0.71 8.1 5.9 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) CE2_N PF17996.1 KIY62883.1 - 0.028 14.4 0.1 0.075 13.0 0.1 1.7 2 0 0 2 2 2 0 Carbohydrate esterase 2 N-terminal GH115_C PF17829.1 KIY62883.1 - 0.046 13.6 0.2 0.46 10.3 0.0 2.3 2 1 0 2 2 2 0 Gylcosyl hydrolase family 115 C-terminal domain HAD_2 PF13419.6 KIY62888.1 - 3.1e-16 59.9 0.0 8.9e-11 42.2 0.0 2.1 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KIY62888.1 - 1.1e-12 48.7 0.0 2.1e-12 47.8 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KIY62888.1 - 9.3e-05 22.4 0.0 0.0002 21.4 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 KIY62888.1 - 0.018 15.5 0.1 0.92 9.9 0.0 3.0 2 1 1 3 3 3 0 haloacid dehalogenase-like hydrolase F-box-like PF12937.7 KIY62890.1 - 7.2e-05 22.6 1.3 0.0044 16.9 0.0 3.9 4 1 0 4 4 4 1 F-box-like F-box PF00646.33 KIY62890.1 - 0.029 14.2 0.1 13 5.9 0.1 2.9 2 0 0 2 2 2 0 F-box domain Epimerase PF01370.21 KIY62891.1 - 2.2e-11 43.7 0.0 2.6e-10 40.2 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KIY62891.1 - 7.8e-10 38.9 0.7 1.2e-09 38.3 0.7 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KIY62891.1 - 5e-08 32.8 0.3 1.5e-07 31.2 0.5 1.7 2 0 0 2 2 2 1 NmrA-like family NAD_binding_4 PF07993.12 KIY62891.1 - 2.2e-07 30.3 0.6 0.0027 16.9 0.5 2.3 2 1 0 2 2 2 2 Male sterility protein Sacchrp_dh_NADP PF03435.18 KIY62891.1 - 1.9e-05 24.9 1.1 3.2e-05 24.2 0.7 1.6 1 1 1 2 2 2 1 Saccharopine dehydrogenase NADP binding domain 3Beta_HSD PF01073.19 KIY62891.1 - 0.0003 19.9 1.3 0.00096 18.2 1.3 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.18 KIY62891.1 - 0.00048 20.4 0.9 0.001 19.3 0.9 1.5 1 0 0 1 1 1 1 TrkA-N domain GDP_Man_Dehyd PF16363.5 KIY62891.1 - 0.0027 17.2 0.2 1.1 8.5 0.1 3.2 2 2 1 3 3 3 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KIY62891.1 - 0.0033 16.6 0.1 1.1 8.2 0.0 2.2 2 0 0 2 2 2 2 RmlD substrate binding domain DapB_N PF01113.20 KIY62891.1 - 0.0064 16.6 0.3 0.011 15.9 0.3 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 KIY62891.1 - 0.023 15.2 0.1 0.039 14.4 0.1 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KIY62891.1 - 0.12 12.5 0.1 0.21 11.6 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase APH PF01636.23 KIY62893.1 - 3.5e-05 23.8 0.1 0.088 12.7 0.1 2.7 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.25 KIY62893.1 - 0.0002 20.8 0.0 0.00034 20.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.20 KIY62893.1 - 0.012 15.2 0.0 0.025 14.1 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase WaaY PF06176.11 KIY62893.1 - 0.031 13.9 0.0 0.053 13.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) GT87 PF09594.10 KIY62894.1 - 0.021 14.6 0.0 0.043 13.5 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 87 IIGP PF05049.13 KIY62896.1 - 1.7e-23 83.3 0.0 3.4e-23 82.3 0.0 1.5 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) MMR_HSR1 PF01926.23 KIY62896.1 - 3.9e-06 26.9 0.0 1.4e-05 25.2 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 KIY62896.1 - 3.3e-05 24.4 2.1 0.00067 20.2 0.0 2.6 2 0 0 2 2 2 1 ABC transporter RsgA_GTPase PF03193.16 KIY62896.1 - 0.00019 21.4 0.7 0.0032 17.4 0.0 2.9 3 0 0 3 3 3 1 RsgA GTPase AAA_22 PF13401.6 KIY62896.1 - 0.00066 20.0 0.0 0.0021 18.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KIY62896.1 - 0.0028 17.4 0.0 0.007 16.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 KIY62896.1 - 0.0049 16.6 0.1 0.0049 16.6 0.1 1.9 2 0 0 2 2 1 1 AAA domain DUF87 PF01935.17 KIY62896.1 - 0.0087 16.2 0.2 0.0087 16.2 0.2 2.9 3 1 0 3 3 3 1 Helicase HerA, central domain AAA_7 PF12775.7 KIY62896.1 - 0.012 15.2 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 KIY62896.1 - 0.013 14.9 0.0 0.038 13.4 0.0 1.8 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI FtsK_SpoIIIE PF01580.18 KIY62896.1 - 0.017 14.5 1.0 0.039 13.3 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family Dynamin_N PF00350.23 KIY62896.1 - 0.028 14.5 0.1 0.028 14.5 0.1 2.7 2 2 0 2 2 1 0 Dynamin family G-alpha PF00503.20 KIY62896.1 - 0.03 13.5 1.3 0.077 12.1 0.0 2.0 2 0 0 2 2 2 0 G-protein alpha subunit AAA_13 PF13166.6 KIY62896.1 - 0.037 12.7 13.3 0.36 9.4 0.0 2.3 1 1 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KIY62896.1 - 0.045 14.2 8.6 0.053 14.0 0.0 2.7 2 0 0 2 2 1 0 AAA domain AAA_16 PF13191.6 KIY62896.1 - 0.049 14.0 2.5 0.16 12.3 0.0 2.7 3 0 0 3 3 2 0 AAA ATPase domain ATP_bind_1 PF03029.17 KIY62896.1 - 0.076 12.8 3.2 2.5 7.8 0.0 3.1 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Roc PF08477.13 KIY62896.1 - 0.082 13.1 0.0 0.22 11.7 0.0 1.8 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase SMC_N PF02463.19 KIY62896.1 - 0.12 11.8 0.6 0.36 10.2 0.0 2.0 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 KIY62896.1 - 0.21 11.8 0.1 0.21 11.8 0.1 4.0 3 2 2 5 5 5 0 AAA domain DUF3987 PF13148.6 KIY62896.1 - 0.25 10.3 0.0 0.25 10.3 0.0 3.5 2 1 2 4 4 4 0 Protein of unknown function (DUF3987) GTP_EFTU PF00009.27 KIY62896.1 - 0.38 10.3 2.4 1.5 8.4 0.0 2.5 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain ERM PF00769.19 KIY62896.1 - 1 9.1 26.5 0.21 11.4 20.9 2.1 2 0 0 2 2 2 0 Ezrin/radixin/moesin family VIR_N PF15912.5 KIY62896.1 - 1.4 8.4 8.5 3.4 7.2 8.5 1.5 1 0 0 1 1 1 0 Virilizer, N-terminal UPF0172 PF03665.13 KIY62896.1 - 2 8.4 6.4 1.9 8.5 0.2 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0172) DUF1664 PF07889.12 KIY62896.1 - 2 8.5 6.3 6.6 6.8 6.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) CDC45 PF02724.14 KIY62896.1 - 2.1 6.5 11.0 3.6 5.8 11.0 1.3 1 0 0 1 1 1 0 CDC45-like protein Gly_acyl_tr_N PF06021.11 KIY62896.1 - 4.7 7.3 6.7 25 4.9 3.2 2.3 2 0 0 2 2 2 0 Aralkyl acyl-CoA:amino acid N-acyltransferase Exonuc_VII_L PF02601.15 KIY62896.1 - 5.7 6.4 12.5 7.9 5.9 10.7 1.9 2 0 0 2 2 2 0 Exonuclease VII, large subunit FUSC PF04632.12 KIY62896.1 - 6.1 5.3 10.6 11 4.4 10.6 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family COX4 PF02936.14 KIY62897.1 - 4.6e-36 123.9 0.0 5.7e-36 123.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV GspH PF12019.8 KIY62897.1 - 0.0097 16.3 0.0 0.016 15.6 0.0 1.4 1 0 0 1 1 1 1 Type II transport protein GspH AAA PF00004.29 KIY62898.1 - 0.00049 20.5 0.1 0.043 14.2 0.0 2.4 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) CDC45 PF02724.14 KIY62898.1 - 1.5 7.0 16.6 1.9 6.7 16.6 1.2 1 0 0 1 1 1 0 CDC45-like protein SAPS PF04499.15 KIY62898.1 - 4.2 6.0 11.9 5.8 5.6 11.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein ALMT PF11744.8 KIY62898.1 - 5.3 5.8 11.4 6.4 5.5 11.4 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Vfa1 PF08432.10 KIY62898.1 - 9 6.6 23.3 22 5.3 23.3 1.7 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Pkinase PF00069.25 KIY62899.1 - 8.7e-68 228.5 0.0 1e-67 228.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY62899.1 - 1.5e-44 152.2 0.0 2.1e-44 151.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY62899.1 - 1.7e-10 40.7 0.0 9.6e-08 31.7 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 KIY62899.1 - 0.0012 18.3 0.0 0.0022 17.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KIY62899.1 - 0.002 17.0 0.0 0.0031 16.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KIY62899.1 - 0.02 14.8 0.0 0.039 13.9 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 KIY62899.1 - 0.16 11.5 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 KIY62899.1 - 0.19 10.6 0.0 0.31 9.9 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Cas1_AcylT PF07779.12 KIY62901.1 - 1.9e-140 468.9 12.0 2.6e-140 468.5 12.0 1.1 1 0 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p PC-Esterase PF13839.6 KIY62901.1 - 0.0001 22.2 0.0 0.00017 21.5 0.0 1.3 1 0 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Rhomboid PF01694.22 KIY62902.1 - 7.4e-32 110.4 15.6 1.5e-31 109.4 15.6 1.6 1 0 0 1 1 1 1 Rhomboid family TMEM43 PF07787.12 KIY62902.1 - 0.6 9.5 4.2 0.76 9.1 0.7 2.3 1 1 1 2 2 2 0 Transmembrane protein 43 TFIID-31kDa PF02291.15 KIY62903.1 - 2.7e-35 121.1 0.0 3.6e-35 120.7 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CENP-T_C PF15511.6 KIY62903.1 - 3.2e-06 27.2 0.0 7.8e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KIY62903.1 - 0.00012 22.4 0.0 0.00024 21.4 0.0 1.4 1 0 0 1 1 1 1 CENP-S protein Bromo_TP PF07524.13 KIY62903.1 - 0.00019 21.3 0.0 0.00043 20.2 0.0 1.5 2 0 0 2 2 2 1 Bromodomain associated Histone PF00125.24 KIY62903.1 - 0.041 14.2 0.0 0.066 13.6 0.0 1.3 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 DAO PF01266.24 KIY62904.1 - 1.3e-14 54.6 0.0 1.4e-14 54.5 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase DHFR_1 PF00186.19 KIY62906.1 - 1.2e-18 67.3 0.0 1.5e-18 67.0 0.0 1.3 1 0 0 1 1 1 1 Dihydrofolate reductase SGS PF05002.15 KIY62907.1 - 1.9e-32 111.2 1.5 2.8e-32 110.6 1.5 1.3 1 0 0 1 1 1 1 SGS domain CS PF04969.16 KIY62907.1 - 4.6e-09 37.2 0.0 7.3e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 CS domain GST_N_3 PF13417.6 KIY62908.1 - 2.2e-12 47.2 0.1 4.7e-12 46.1 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KIY62908.1 - 7.4e-08 32.6 0.0 1.3e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KIY62908.1 - 7.1e-05 22.8 0.0 0.0003 20.7 0.0 1.9 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KIY62908.1 - 7.8e-05 22.9 0.0 0.00018 21.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KIY62908.1 - 0.0015 18.7 0.0 0.0042 17.3 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KIY62908.1 - 0.015 15.5 0.0 0.047 13.9 0.0 2.0 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Sialidase PF02973.16 KIY62908.1 - 0.032 13.7 0.2 0.12 11.8 0.1 1.9 1 1 1 2 2 2 0 Sialidase, N-terminal domain LpqV PF17301.2 KIY62908.1 - 0.44 10.8 0.0 0.44 10.8 0.0 2.1 2 0 0 2 2 2 0 Putative lipoprotein LpqV Galactosyl_T PF01762.21 KIY62909.1 - 1.1e-11 44.9 0.0 3.5e-06 27.0 0.0 2.2 2 0 0 2 2 2 2 Galactosyltransferase Glyco_trans_2_3 PF13632.6 KIY62909.1 - 1.3 8.9 4.4 0.59 10.0 1.2 2.0 2 0 0 2 2 2 0 Glycosyl transferase family group 2 Pkinase PF00069.25 KIY62910.1 - 6.6e-28 97.8 0.0 1.8e-13 50.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIY62910.1 - 4.3e-13 49.1 0.0 4.8e-08 32.6 0.0 2.6 3 0 0 3 3 3 2 Protein tyrosine kinase Kdo PF06293.14 KIY62910.1 - 0.014 14.8 0.0 0.025 13.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KIY62910.1 - 0.096 12.3 0.0 2 8.0 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 KIY62910.1 - 0.15 11.4 0.0 5.5 6.2 0.0 2.6 3 0 0 3 3 3 0 Kinase-like Pkinase PF00069.25 KIY62911.1 - 1.4e-26 93.5 0.0 2.6e-12 46.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIY62911.1 - 8.2e-13 48.2 0.0 1.3e-07 31.2 0.0 2.6 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 KIY62911.1 - 0.0035 17.3 0.7 1.1 9.1 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Calici_PP_N PF08405.11 KIY62911.1 - 0.047 12.5 0.0 0.071 11.9 0.0 1.2 1 0 0 1 1 1 0 Viral polyprotein N-terminal XPG_I PF00867.18 KIY62912.1 - 1.3e-15 57.5 0.0 6.7e-14 52.0 0.0 2.4 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.17 KIY62912.1 - 6.2e-05 23.4 0.0 0.00018 21.9 0.0 1.8 1 1 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.20 KIY62912.1 - 0.0035 17.9 0.0 0.01 16.4 0.0 1.8 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HHH_2 PF12826.7 KIY62912.1 - 0.17 12.0 0.0 0.5 10.5 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif Pro-kuma_activ PF09286.11 KIY62913.1 - 6.6e-37 127.0 0.2 1.2e-36 126.1 0.2 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KIY62913.1 - 3.4e-08 33.1 3.2 5e-08 32.6 3.2 1.3 1 0 0 1 1 1 1 Subtilase family Pkinase PF00069.25 KIY62914.1 - 1.2e-24 87.2 0.0 3e-11 43.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIY62914.1 - 5.7e-12 45.5 0.0 1.1e-08 34.7 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KIY62914.1 - 0.0055 16.7 0.7 0.4 10.6 0.5 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KIY62914.1 - 0.088 12.2 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sec23_trunk PF04811.15 KIY62915.1 - 7.5e-72 241.8 0.0 1.7e-71 240.6 0.0 1.6 2 0 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 KIY62915.1 - 1e-22 79.9 0.0 5e-22 77.7 0.1 2.2 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 KIY62915.1 - 1.2e-17 64.4 0.1 2.9e-17 63.2 0.1 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 KIY62915.1 - 2.8e-16 59.2 8.1 5.1e-16 58.4 8.1 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger WW PF00397.26 KIY62915.1 - 1.9e-09 37.5 1.0 1.9e-09 37.5 1.0 2.2 2 0 0 2 2 2 1 WW domain Gelsolin PF00626.22 KIY62915.1 - 8.8e-09 35.2 0.0 1.6e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 KIY62915.1 - 0.006 15.9 0.9 0.012 15.0 0.9 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain XPG_I PF00867.18 KIY62917.1 - 2.4e-11 43.8 0.0 3.7e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.20 KIY62917.1 - 0.002 18.7 0.0 0.0031 18.1 0.0 1.3 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold HHH_2 PF12826.7 KIY62917.1 - 0.036 14.1 0.0 0.074 13.2 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif HHH_5 PF14520.6 KIY62917.1 - 0.077 13.6 0.0 0.14 12.8 0.0 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix domain Pkinase PF00069.25 KIY62919.1 - 3.6e-20 72.4 0.0 1.3e-10 41.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIY62919.1 - 1.7e-07 30.8 0.0 0.011 15.0 0.0 2.9 3 0 0 3 3 3 2 Protein tyrosine kinase zf-MYND PF01753.18 KIY62920.1 - 9.9e-07 28.7 15.5 3.1e-06 27.2 15.5 1.9 1 1 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 KIY62920.1 - 0.29 11.2 8.0 0.8 9.8 8.0 1.8 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 DUF4112 PF13430.6 KIY62921.1 - 5.7e-33 113.3 0.1 7.7e-33 112.9 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) YbhQ PF11076.8 KIY62921.1 - 0.1 12.6 0.1 0.15 12.1 0.1 1.2 1 0 0 1 1 1 0 Putative inner membrane protein YbhQ OHCU_decarbox PF09349.10 KIY62922.1 - 1.1e-39 136.5 0.0 1.3e-39 136.2 0.0 1.0 1 0 0 1 1 1 1 OHCU decarboxylase DnaJ PF00226.31 KIY62923.1 - 1.5e-11 44.2 0.4 3.4e-11 43.1 0.4 1.6 1 0 0 1 1 1 1 DnaJ domain ANAPC15 PF15243.6 KIY62923.1 - 0.0024 18.2 0.5 0.0024 18.2 0.5 1.5 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 15 Transcrip_act PF04949.13 KIY62923.1 - 0.0071 16.2 0.7 0.0071 16.2 0.7 1.5 2 0 0 2 2 2 1 Transcriptional activator T3SSipB PF16535.5 KIY62923.1 - 0.085 13.3 0.5 0.085 13.3 0.5 1.9 1 1 1 2 2 2 0 Type III cell invasion protein SipB Tho2 PF11262.8 KIY62923.1 - 0.29 10.3 4.0 0.27 10.4 3.2 1.2 1 1 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 YlqD PF11068.8 KIY62923.1 - 1.2 9.5 5.4 1.7 9.1 5.3 1.4 1 1 0 1 1 1 0 YlqD protein Efg1 PF10153.9 KIY62923.1 - 4.3 7.7 8.2 17 5.8 0.1 2.9 3 0 0 3 3 3 0 rRNA-processing protein Efg1 LRR_5 PF13306.6 KIY62924.1 - 0.051 13.5 0.1 0.2 11.6 0.1 1.9 2 0 0 2 2 2 0 BspA type Leucine rich repeat region (6 copies) CS PF04969.16 KIY62928.1 - 9.4e-11 42.6 0.0 2e-10 41.6 0.0 1.6 1 0 0 1 1 1 1 CS domain PQQ_3 PF13570.6 KIY62928.1 - 0.19 12.3 1.5 0.75 10.4 0.1 2.7 3 0 0 3 3 3 0 PQQ-like domain zf-MYND PF01753.18 KIY62930.1 - 5e-06 26.5 4.5 9.5e-06 25.6 4.5 1.5 1 0 0 1 1 1 1 MYND finger C5HCH PF17982.1 KIY62930.1 - 0.12 12.5 7.3 0.17 12.1 4.0 2.2 2 0 0 2 2 2 0 NSD Cys-His rich domain zf-Mss51 PF13824.6 KIY62930.1 - 0.13 12.3 8.8 0.058 13.5 5.4 2.0 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-HIT PF04438.16 KIY62930.1 - 1.5 8.7 9.7 3.6 7.5 9.7 1.6 1 0 0 1 1 1 0 HIT zinc finger SET PF00856.28 KIY62931.1 - 7.7e-20 71.9 0.5 1.2e-17 64.8 0.0 3.2 2 1 0 2 2 2 1 SET domain Pre-SET PF05033.16 KIY62931.1 - 2.5e-07 31.3 5.5 2.5e-07 31.3 5.5 2.5 2 0 0 2 2 2 1 Pre-SET motif zf-RanBP PF00641.18 KIY62932.1 - 0.0024 17.1 10.9 0.06 12.7 0.8 2.6 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others C1_2 PF03107.16 KIY62932.1 - 4.1 7.8 5.6 2.7 8.4 0.6 2.4 2 0 0 2 2 2 0 C1 domain NADH-u_ox-rdase PF10785.9 KIY62933.1 - 3.3e-27 95.0 0.0 4.8e-27 94.5 0.0 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.7 KIY62933.1 - 6.4e-14 51.7 0.0 9.3e-14 51.2 0.0 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit DUF1634 PF07843.11 KIY62933.1 - 0.052 13.6 0.0 0.082 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1634) DUF3899 PF13038.6 KIY62933.1 - 0.07 13.6 0.0 0.1 13.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3899) DPBB_1 PF03330.18 KIY62934.1 - 0.041 14.2 0.5 0.086 13.1 0.5 1.6 1 1 0 1 1 1 0 Lytic transglycolase DUF2946 PF11162.8 KIY62934.1 - 0.058 14.1 0.5 0.058 14.1 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2946) zf-TFIIB PF13453.6 KIY62934.1 - 8.4 5.8 7.3 0.96 8.8 0.4 2.5 3 0 0 3 3 3 0 Transcription factor zinc-finger Glyco_hydro_31 PF01055.26 KIY62937.1 - 2.5e-152 508.1 2.5 3.1e-152 507.8 2.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 KIY62937.1 - 9.3e-37 125.8 0.1 1.8e-36 124.8 0.1 1.4 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 KIY62937.1 - 1.2e-12 47.9 0.5 1.2e-12 47.9 0.5 2.2 2 0 0 2 2 2 1 Galactose mutarotase-like Aldose_epim PF01263.20 KIY62938.1 - 3.7e-26 92.1 0.0 4.2e-26 92.0 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase PMT PF02366.18 KIY62939.1 - 1.8e-81 273.4 17.2 1.8e-81 273.4 17.2 1.6 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KIY62939.1 - 5e-61 205.8 6.7 5e-61 205.8 6.7 3.4 2 1 1 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KIY62939.1 - 3.1e-16 59.8 1.1 4.6e-16 59.2 1.1 1.2 1 0 0 1 1 1 1 MIR domain PMT_2 PF13231.6 KIY62939.1 - 5.3e-09 36.5 10.7 5.3e-09 36.5 10.7 2.3 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase DsbD_2 PF13386.6 KIY62939.1 - 0.05 13.5 2.7 1.6 8.6 0.1 2.7 2 0 0 2 2 2 0 Cytochrome C biogenesis protein transmembrane region E1-E2_ATPase PF00122.20 KIY62940.1 - 1.3e-47 161.7 1.9 1.3e-47 161.7 1.9 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 KIY62940.1 - 1.3e-31 110.5 2.4 1.3e-31 110.5 2.4 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 KIY62940.1 - 2.5e-26 91.9 0.0 6.5e-12 45.7 0.0 2.8 2 0 0 2 2 2 2 Heavy-metal-associated domain Hydrolase_3 PF08282.12 KIY62940.1 - 3.1e-05 23.8 1.6 0.0032 17.3 0.4 2.3 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase DUF1230 PF06799.11 KIY62940.1 - 0.0056 16.8 0.1 0.02 15.0 0.1 1.9 1 0 0 1 1 1 1 Conserved in the green lineage and diatoms 27 HAD PF12710.7 KIY62940.1 - 0.16 12.4 0.1 13 6.2 0.0 2.7 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Methyltransf_23 PF13489.6 KIY62941.1 - 3e-24 85.7 0.0 4e-24 85.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIY62941.1 - 3.2e-19 69.4 0.0 5.1e-19 68.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIY62941.1 - 1.8e-15 57.4 0.0 3e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIY62941.1 - 7.1e-14 51.9 0.0 9.5e-14 51.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIY62941.1 - 1.9e-13 51.0 0.0 3e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KIY62941.1 - 3.4e-09 36.4 0.0 4.4e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 KIY62941.1 - 1.5e-07 30.7 0.0 2.1e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PrmA PF06325.13 KIY62941.1 - 4.9e-07 29.4 0.0 7.4e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) NodS PF05401.11 KIY62941.1 - 0.00027 20.6 0.0 0.00038 20.1 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Ubie_methyltran PF01209.18 KIY62941.1 - 0.00068 19.0 0.0 0.00093 18.6 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_15 PF09445.10 KIY62941.1 - 0.00072 19.2 0.0 0.0011 18.5 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_32 PF13679.6 KIY62941.1 - 0.00079 19.4 0.0 0.0011 19.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KIY62941.1 - 0.001 18.6 0.0 0.0016 18.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.9 KIY62941.1 - 0.0026 17.5 0.1 0.0055 16.5 0.1 1.4 1 1 0 1 1 1 1 Lysine methyltransferase MetW PF07021.12 KIY62941.1 - 0.0042 16.7 0.0 0.0075 15.9 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW DREV PF05219.12 KIY62941.1 - 0.0045 16.1 0.0 0.0065 15.6 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase Cons_hypoth95 PF03602.15 KIY62941.1 - 0.0075 15.9 0.0 0.033 13.8 0.0 1.8 2 0 0 2 2 2 1 Conserved hypothetical protein 95 TehB PF03848.14 KIY62941.1 - 0.015 14.7 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB ADH_zinc_N PF00107.26 KIY62941.1 - 0.053 13.5 0.0 0.082 12.9 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase TPMT PF05724.11 KIY62941.1 - 0.056 13.1 0.0 0.18 11.4 0.0 1.8 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) AdoMet_MTase PF07757.13 KIY62941.1 - 0.11 12.8 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase DUF4139 PF13598.6 KIY62942.1 - 1.7e-45 155.3 0.0 4.6e-45 153.9 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4139) DUF4140 PF13600.6 KIY62942.1 - 1.9e-17 63.5 1.8 3.2e-16 59.5 0.0 2.9 2 1 1 3 3 3 1 N-terminal domain of unknown function (DUF4140) Ribosomal_60s PF00428.19 KIY62942.1 - 0.0002 21.9 0.3 0.00071 20.1 0.3 1.9 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF5082 PF16888.5 KIY62942.1 - 0.0078 16.5 0.5 0.015 15.5 0.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5082) FliJ PF02050.16 KIY62942.1 - 0.017 15.3 1.5 0.033 14.4 1.5 1.4 1 0 0 1 1 1 0 Flagellar FliJ protein DOPA_dioxygen PF08883.11 KIY62943.1 - 4e-46 155.6 0.1 5e-46 155.3 0.1 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family PH_10 PF15411.6 KIY62944.1 - 2.5e-24 85.9 0.0 4.1e-24 85.2 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain zf-RING_2 PF13639.6 KIY62944.1 - 0.00011 22.4 1.0 0.00025 21.3 1.1 1.6 1 1 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KIY62944.1 - 0.00019 21.4 1.4 0.00047 20.1 1.4 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KIY62944.1 - 0.0014 18.5 0.8 0.0027 17.6 0.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain VWA PF00092.28 KIY62944.1 - 0.0018 18.6 0.0 0.0088 16.3 0.0 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_3 PF13768.6 KIY62944.1 - 0.0041 17.1 0.0 0.011 15.7 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain Cys_rich_CPXG PF14255.6 KIY62944.1 - 0.2 11.6 0.4 0.67 9.9 0.0 2.0 2 0 0 2 2 2 0 Cysteine-rich CPXCG zf-C3HC4 PF00097.25 KIY62944.1 - 0.23 11.4 0.1 0.5 10.3 0.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KIY62944.1 - 0.36 10.6 4.6 0.28 10.9 2.5 2.0 2 0 0 2 2 2 0 RING-like zinc finger zf-C3HC4_2 PF13923.6 KIY62944.1 - 0.69 9.8 1.7 2.5 8.0 1.7 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PALP PF00291.25 KIY62945.1 - 1.9e-54 185.1 0.2 2.1e-54 184.9 0.2 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme UPF0016 PF01169.19 KIY62947.1 - 1.2e-06 28.7 0.2 1.9e-06 28.1 0.2 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0016 EDR1 PF14381.6 KIY62947.1 - 0.031 14.0 0.0 0.034 13.8 0.0 1.1 1 0 0 1 1 1 0 Ethylene-responsive protein kinase Le-CTR1 Ribosomal_L44 PF00935.19 KIY62948.1 - 4.3e-09 36.7 1.1 7.5e-09 35.9 1.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 Rhodanese PF00581.20 KIY62948.1 - 0.12 12.9 0.0 0.18 12.3 0.0 1.3 1 0 0 1 1 1 0 Rhodanese-like domain Glyco_hydro_18 PF00704.28 KIY62950.1 - 2.5e-45 155.6 0.0 2.9e-45 155.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Fer4_9 PF13187.6 KIY62951.1 - 0.63 10.3 9.4 13 6.0 9.4 2.4 1 1 0 1 1 1 0 4Fe-4S dicluster domain F-box-like PF12937.7 KIY62952.1 - 1.5e-10 40.8 1.5 3.9e-10 39.5 0.5 2.4 2 0 0 2 2 2 1 F-box-like USP8_interact PF08941.10 KIY62952.1 - 0.01 15.7 0.4 2 8.2 0.0 2.3 2 0 0 2 2 2 2 USP8 interacting F-box PF00646.33 KIY62952.1 - 0.056 13.3 1.5 0.18 11.7 0.1 2.7 2 0 0 2 2 2 0 F-box domain Pkinase PF00069.25 KIY62953.1 - 4e-44 150.9 0.0 5.5e-44 150.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY62953.1 - 1.7e-26 93.0 0.0 2.5e-26 92.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIY62953.1 - 0.0056 15.5 0.0 0.0056 15.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KIY62953.1 - 0.0086 16.0 0.6 0.019 14.9 0.2 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 KIY62953.1 - 0.04 13.6 0.0 1.7 8.2 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DEAD PF00270.29 KIY62954.1 - 2e-47 161.2 0.0 9e-47 159.1 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIY62954.1 - 3.5e-29 101.4 0.0 2.2e-28 98.8 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIY62954.1 - 0.00015 21.9 0.0 0.00046 20.2 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit EF-hand_7 PF13499.6 KIY62955.1 - 0.00018 21.9 0.9 0.006 17.0 0.9 2.2 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 KIY62955.1 - 0.0049 16.7 0.2 0.0083 16.0 0.1 1.4 1 1 0 1 1 1 1 EF-hand domain pair p25-alpha PF05517.12 KIY62955.1 - 0.024 14.8 0.0 0.03 14.5 0.0 1.1 1 0 0 1 1 1 0 p25-alpha EF_assoc_1 PF08355.12 KIY62955.1 - 0.074 12.7 0.0 0.15 11.7 0.0 1.6 2 0 0 2 2 2 0 EF hand associated YfkB PF08756.10 KIY62955.1 - 0.11 12.3 0.0 0.7 9.7 0.0 1.9 1 1 1 2 2 2 0 YfkB-like domain PRKCSH PF07915.13 KIY62956.1 - 4e-14 53.4 0.7 7e-14 52.6 0.7 1.4 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 KIY62956.1 - 0.0014 18.3 0.1 0.0029 17.3 0.0 1.5 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein DUF5561 PF17716.1 KIY62956.1 - 0.18 11.1 0.0 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5561) AT_hook PF02178.19 KIY62957.1 - 0.12 12.3 45.6 0.33 11.0 5.4 4.0 4 0 0 4 4 4 0 AT hook motif FAD_binding_3 PF01494.19 KIY62958.1 - 6.6e-17 61.8 0.0 2.5e-16 59.9 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KIY62958.1 - 2.4e-06 27.4 0.0 0.00014 21.6 0.2 2.1 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KIY62958.1 - 6.7e-05 23.0 0.0 0.00015 21.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KIY62958.1 - 0.0002 20.6 0.1 0.00026 20.2 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 KIY62958.1 - 0.00021 20.6 0.0 0.00054 19.3 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIY62958.1 - 0.00029 21.3 0.0 0.0061 17.1 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KIY62958.1 - 0.0018 17.1 0.0 0.0029 16.4 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 KIY62958.1 - 0.021 14.0 0.8 0.032 13.3 0.8 1.5 1 1 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.7 KIY62958.1 - 0.028 13.8 1.1 0.067 12.5 0.6 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase ApbA PF02558.16 KIY62958.1 - 0.082 12.6 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA MitoNEET_N PF10660.9 KIY62958.1 - 0.16 12.0 0.0 0.84 9.7 0.0 2.1 2 0 0 2 2 2 0 Iron-containing outer mitochondrial membrane protein N-terminus Pyr_redox_3 PF13738.6 KIY62958.1 - 0.25 10.5 0.0 2.3 7.4 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Aminotran_5 PF00266.19 KIY62959.1 - 2.5e-11 43.1 0.0 3.3e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V PIF1 PF05970.14 KIY62960.1 - 0.00032 20.0 0.0 0.00039 19.7 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase SH3_13 PF18335.1 KIY62960.1 - 0.022 14.6 0.0 0.07 13.0 0.0 1.8 2 0 0 2 2 2 0 ATP-dependent RecD-like DNA helicase SH3 domain AAA_30 PF13604.6 KIY62961.1 - 2.1e-11 43.9 0.0 2.3e-11 43.8 0.0 1.0 1 0 0 1 1 1 1 AAA domain PIF1 PF05970.14 KIY62961.1 - 2.6e-10 40.0 0.0 2.8e-10 39.9 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_19 PF13245.6 KIY62961.1 - 1.6e-08 35.0 0.0 1.7e-08 34.9 0.0 1.0 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KIY62961.1 - 0.0048 16.7 0.6 0.093 12.5 0.6 2.0 1 1 0 1 1 1 1 IstB-like ATP binding protein AAA_5 PF07728.14 KIY62961.1 - 0.0082 16.1 0.0 0.01 15.8 0.0 1.1 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KIY62961.1 - 0.0089 16.3 0.1 0.031 14.5 0.1 1.8 1 1 0 1 1 1 1 AAA domain DEAD PF00270.29 KIY62961.1 - 0.021 14.6 0.1 0.55 10.0 0.0 2.0 1 1 0 1 1 1 0 DEAD/DEAH box helicase Bac_DnaA PF00308.18 KIY62961.1 - 0.04 13.7 0.0 0.11 12.3 0.0 1.6 1 1 0 1 1 1 0 Bacterial dnaA protein AAA_11 PF13086.6 KIY62961.1 - 0.07 12.9 0.0 0.25 11.1 0.0 1.7 1 1 1 2 2 2 0 AAA domain ResIII PF04851.15 KIY62961.1 - 0.095 12.7 0.0 0.65 10.0 0.0 1.8 1 1 0 2 2 2 0 Type III restriction enzyme, res subunit RNA_helicase PF00910.22 KIY62961.1 - 0.12 12.8 0.3 1.2 9.5 0.3 2.0 1 1 0 1 1 1 0 RNA helicase NACHT PF05729.12 KIY62961.1 - 0.15 12.0 0.0 0.2 11.6 0.0 1.1 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.6 KIY62961.1 - 0.19 12.1 0.0 0.22 11.9 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_21 PF13304.6 KIY62961.1 - 0.19 11.5 0.0 0.25 11.1 0.0 1.4 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Helitron_like_N PF14214.6 KIY62963.1 - 9.4e-22 78.2 0.1 1.1e-21 77.9 0.1 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus p450 PF00067.22 KIY62969.1 - 4.7e-60 203.6 0.0 8e-60 202.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.18 KIY62970.1 - 1.2e-20 73.7 0.6 1.6e-20 73.2 0.6 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain UQ_con PF00179.26 KIY62972.1 - 1.5e-42 144.6 0.0 1.8e-42 144.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.10 KIY62972.1 - 4.9e-18 64.7 0.3 8.4e-18 63.9 0.3 1.4 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain UBA_6 PF18039.1 KIY62972.1 - 0.004 17.1 0.0 0.0074 16.2 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain Prok-E2_B PF14461.6 KIY62972.1 - 0.0078 15.9 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B UBA PF00627.31 KIY62972.1 - 0.04 13.8 0.0 0.087 12.8 0.0 1.6 1 0 0 1 1 1 0 UBA/TS-N domain Hydant_A_N PF05378.13 KIY62972.1 - 0.074 12.8 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase N-terminal region DUF1421 PF07223.11 KIY62972.1 - 0.12 12.2 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 UBA-like domain (DUF1421) TMEM100 PF16311.5 KIY62975.1 - 0.0085 15.7 0.4 0.025 14.2 0.0 1.9 2 0 0 2 2 2 1 Transmembrane protein 100 Pox_Ag35 PF03286.14 KIY62975.1 - 0.011 15.6 15.2 0.02 14.7 15.2 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Nop14 PF04147.12 KIY62975.1 - 0.032 12.5 20.3 0.043 12.0 20.3 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 KIY62975.1 - 0.082 11.2 20.3 0.12 10.7 20.3 1.1 1 0 0 1 1 1 0 CDC45-like protein TFIIF_alpha PF05793.12 KIY62975.1 - 0.083 11.5 26.8 0.16 10.5 26.8 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF1682 PF07946.14 KIY62975.1 - 0.095 11.9 3.3 0.14 11.3 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Mpp10 PF04006.12 KIY62975.1 - 0.11 10.9 21.8 0.16 10.4 21.8 1.1 1 0 0 1 1 1 0 Mpp10 protein PTPRCAP PF15713.5 KIY62975.1 - 0.15 12.4 18.9 0.29 11.4 18.9 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated DUF2370 PF10176.9 KIY62975.1 - 0.16 11.6 0.3 39 3.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) SDA1 PF05285.12 KIY62975.1 - 0.28 10.6 23.9 0.43 10.0 23.9 1.2 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 KIY62975.1 - 0.35 10.2 22.5 0.54 9.5 22.5 1.2 1 0 0 1 1 1 0 BUD22 Tub_N PF16322.5 KIY62975.1 - 0.4 11.1 18.2 1.2 9.5 18.2 1.8 1 0 0 1 1 1 0 Tubby N-terminal Paf1 PF03985.13 KIY62975.1 - 0.52 9.3 19.3 0.76 8.7 19.3 1.1 1 0 0 1 1 1 0 Paf1 DUF4448 PF14610.6 KIY62975.1 - 0.61 9.8 0.0 0.61 9.8 0.0 2.1 2 1 0 2 2 1 0 Protein of unknown function (DUF4448) PI3K_1B_p101 PF10486.9 KIY62975.1 - 1 7.0 13.0 1.4 6.6 13.0 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit PPP4R2 PF09184.11 KIY62975.1 - 1 8.9 18.5 2 7.9 18.5 1.5 1 0 0 1 1 1 0 PPP4R2 RR_TM4-6 PF06459.12 KIY62975.1 - 1.5 8.6 13.4 2.5 7.9 13.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NPR3 PF03666.13 KIY62975.1 - 1.5 7.5 13.5 2.3 6.9 13.5 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Zip PF02535.22 KIY62975.1 - 1.6 7.8 6.8 2.7 7.1 6.8 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Serinc PF03348.15 KIY62975.1 - 1.8 7.4 5.6 25 3.7 3.8 2.1 2 0 0 2 2 2 0 Serine incorporator (Serinc) DNA_pol_phi PF04931.13 KIY62975.1 - 2.4 6.1 27.4 3.2 5.7 27.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF913 PF06025.12 KIY62975.1 - 2.8 6.8 8.6 4.3 6.2 8.6 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) TFB6 PF17110.5 KIY62975.1 - 2.9 7.6 9.8 5.2 6.8 9.8 1.4 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Hid1 PF12722.7 KIY62975.1 - 3.1 5.8 6.0 4.2 5.4 6.0 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SAPS PF04499.15 KIY62975.1 - 3.1 6.5 9.3 4.2 6.1 9.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CPSF100_C PF13299.6 KIY62975.1 - 3.3 7.9 9.8 7.9 6.6 9.8 1.6 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF4637 PF15470.6 KIY62975.1 - 5.4 6.7 20.9 10 5.8 20.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) MCM_bind PF09739.9 KIY62975.1 - 6.1 5.2 12.5 8.7 4.7 12.5 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Vfa1 PF08432.10 KIY62975.1 - 6.8 7.0 19.7 12 6.2 19.7 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Peptidase_S28 PF05577.12 KIY62976.1 - 2.8e-48 164.8 0.0 5.3e-48 163.9 0.0 1.4 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Alpha_kinase PF02816.18 KIY62978.1 - 4.3e-12 46.5 0.0 5.2e-12 46.3 0.0 1.1 1 0 0 1 1 1 1 Alpha-kinase family BAGE PF08180.11 KIY62978.1 - 1.3 9.2 4.6 0.83 9.8 0.5 2.2 2 0 0 2 2 2 0 B melanoma antigen family Y_phosphatase PF00102.27 KIY62980.1 - 7.7e-51 172.9 0.0 1.9e-43 148.7 0.0 3.2 2 1 0 2 2 2 2 Protein-tyrosine phosphatase Rhodanese PF00581.20 KIY62980.1 - 2.7e-08 34.3 0.0 6.2e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain Y_phosphatase3 PF13350.6 KIY62980.1 - 0.12 12.3 0.1 0.24 11.4 0.1 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family F-box-like PF12937.7 KIY62981.1 - 2.2e-06 27.4 0.0 1.1e-05 25.2 0.0 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIY62981.1 - 0.031 14.2 0.6 0.33 10.9 0.1 3.0 2 1 0 2 2 2 0 F-box domain CALCOCO1 PF07888.11 KIY62982.1 - 5.6e-07 28.8 8.3 6.4e-07 28.6 8.3 1.1 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like CENP-H PF05837.12 KIY62982.1 - 7.5e-05 23.1 10.2 0.0018 18.7 1.7 2.2 1 1 1 2 2 2 2 Centromere protein H (CENP-H) YabA PF06156.13 KIY62982.1 - 0.00011 22.7 6.5 0.026 15.1 0.7 2.5 1 1 1 2 2 2 2 Initiation control protein YabA zf-C4H2 PF10146.9 KIY62982.1 - 0.00011 22.5 0.4 0.00014 22.3 0.4 1.2 1 0 0 1 1 1 1 Zinc finger-containing protein CENP-F_leu_zip PF10473.9 KIY62982.1 - 0.00017 21.6 8.9 0.026 14.6 5.5 2.1 1 1 1 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ERM PF00769.19 KIY62982.1 - 0.00017 21.5 9.6 0.00021 21.2 9.6 1.1 1 0 0 1 1 1 1 Ezrin/radixin/moesin family MscS_porin PF12795.7 KIY62982.1 - 0.00033 20.3 13.1 0.00054 19.6 13.1 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain Cast PF10174.9 KIY62982.1 - 0.00055 18.3 4.9 0.0006 18.2 4.9 1.0 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone GAS PF13851.6 KIY62982.1 - 0.00065 19.1 9.4 0.0011 18.4 9.1 1.5 1 1 0 1 1 1 1 Growth-arrest specific micro-tubule binding PRKG1_interact PF15898.5 KIY62982.1 - 0.00088 20.1 11.3 0.28 12.1 11.0 2.3 2 0 0 2 2 2 1 cGMP-dependent protein kinase interacting domain APG6_N PF17675.1 KIY62982.1 - 0.0027 18.3 14.8 0.013 16.1 14.4 1.9 1 1 0 1 1 1 1 Apg6 coiled-coil region ATG16 PF08614.11 KIY62982.1 - 0.005 17.1 13.0 0.0094 16.2 13.0 1.5 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) SCP-1 PF05483.12 KIY62982.1 - 0.0054 14.8 2.3 0.0065 14.5 2.3 1.1 1 0 0 1 1 1 1 Synaptonemal complex protein 1 (SCP-1) WEMBL PF05701.11 KIY62982.1 - 0.006 15.3 7.0 0.0076 15.0 7.0 1.0 1 0 0 1 1 1 1 Weak chloroplast movement under blue light bZIP_1 PF00170.21 KIY62982.1 - 0.0077 16.3 11.5 0.0085 16.2 6.4 3.2 2 1 2 4 4 4 1 bZIP transcription factor DUF3450 PF11932.8 KIY62982.1 - 0.017 14.4 8.5 0.069 12.5 8.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Seryl_tRNA_N PF02403.22 KIY62982.1 - 0.018 15.3 2.0 0.018 15.3 2.0 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain FlaC_arch PF05377.11 KIY62982.1 - 0.019 15.3 1.1 0.17 12.3 0.2 2.7 2 2 1 3 3 3 0 Flagella accessory protein C (FlaC) Fez1 PF06818.15 KIY62982.1 - 0.019 15.4 10.8 0.079 13.4 10.8 1.8 1 1 0 1 1 1 0 Fez1 DUF4200 PF13863.6 KIY62982.1 - 0.024 15.0 10.3 0.039 14.3 10.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) Sec2p PF06428.11 KIY62982.1 - 0.03 14.3 5.8 0.36 10.8 1.8 3.1 2 1 1 3 3 3 0 GDP/GTP exchange factor Sec2p HMMR_N PF15905.5 KIY62982.1 - 0.03 13.8 7.1 0.044 13.3 7.1 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Sipho_Gp157 PF05565.11 KIY62982.1 - 0.042 13.9 5.1 0.059 13.4 5.1 1.3 1 0 0 1 1 1 0 Siphovirus Gp157 DUF2203 PF09969.9 KIY62982.1 - 0.045 14.5 5.7 0.047 14.4 3.6 1.8 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF4483 PF14825.6 KIY62982.1 - 0.045 13.5 1.0 0.078 12.7 1.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4483) SHE3 PF17078.5 KIY62982.1 - 0.046 13.4 7.2 0.063 13.0 6.6 1.5 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 Syntaxin-6_N PF09177.11 KIY62982.1 - 0.051 14.1 3.4 0.075 13.6 3.0 1.6 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Myosin_tail_1 PF01576.19 KIY62982.1 - 0.054 11.3 11.1 0.11 10.3 11.1 1.4 1 1 0 1 1 1 0 Myosin tail TACC_C PF05010.14 KIY62982.1 - 0.055 13.2 8.0 0.1 12.4 5.8 2.2 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DivIC PF04977.15 KIY62982.1 - 0.062 13.1 0.8 0.062 13.1 0.8 3.2 2 1 2 4 4 4 0 Septum formation initiator Nup54 PF13874.6 KIY62982.1 - 0.065 13.3 10.7 0.098 12.8 10.7 1.3 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 FapA PF03961.13 KIY62982.1 - 0.074 11.7 4.2 0.098 11.2 4.2 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A FUSC PF04632.12 KIY62982.1 - 0.077 11.5 4.3 0.09 11.3 4.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Gp-FAR-1 PF05823.12 KIY62982.1 - 0.09 13.1 1.9 0.15 12.4 1.9 1.4 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) TMF_TATA_bd PF12325.8 KIY62982.1 - 0.094 12.9 10.3 2.1 8.6 7.0 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF1664 PF07889.12 KIY62982.1 - 0.097 12.7 1.2 0.27 11.3 0.9 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Cnn_1N PF07989.11 KIY62982.1 - 0.11 12.7 7.6 0.081 13.1 3.3 2.6 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 ZapB PF06005.12 KIY62982.1 - 0.13 12.7 12.6 0.76 10.3 1.1 2.9 1 1 1 2 2 2 0 Cell division protein ZapB Vps51 PF08700.11 KIY62982.1 - 0.14 12.2 3.9 1.2 9.2 4.0 2.4 1 1 0 1 1 1 0 Vps51/Vps67 DUF1843 PF08898.10 KIY62982.1 - 0.16 12.5 5.7 0.26 11.8 0.3 2.9 2 1 1 3 3 2 0 Domain of unknown function (DUF1843) DUF812 PF05667.11 KIY62982.1 - 0.16 10.8 5.8 0.21 10.4 5.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) TSC22 PF01166.18 KIY62982.1 - 0.16 12.3 3.7 38 4.7 0.9 3.2 1 1 2 3 3 3 0 TSC-22/dip/bun family Effector_1 PF04518.12 KIY62982.1 - 0.17 11.0 0.9 0.21 10.7 0.9 1.1 1 0 0 1 1 1 0 Effector from type III secretion system DUF3584 PF12128.8 KIY62982.1 - 0.25 8.8 8.4 0.28 8.7 8.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF724 PF05266.14 KIY62982.1 - 0.25 11.2 8.8 0.28 11.0 8.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF724) HAUS6_N PF14661.6 KIY62982.1 - 0.28 10.7 5.8 0.37 10.3 5.8 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus HMMR_C PF15908.5 KIY62982.1 - 0.32 11.3 8.8 0.6 10.4 0.4 2.8 1 1 2 3 3 3 0 Hyaluronan mediated motility receptor C-terminal Spc7 PF08317.11 KIY62982.1 - 0.41 9.5 12.8 0.16 10.8 9.9 1.6 1 1 1 2 2 2 0 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 KIY62982.1 - 0.5 10.4 13.7 4 7.5 11.2 2.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Uso1_p115_C PF04871.13 KIY62982.1 - 0.51 10.7 13.9 0.72 10.2 10.7 2.4 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region KASH_CCD PF14662.6 KIY62982.1 - 0.51 10.1 11.2 2.4 8.0 0.2 2.0 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH SlyX PF04102.12 KIY62982.1 - 0.55 10.9 8.4 2.7 8.7 0.8 2.8 1 1 2 3 3 2 0 SlyX ADIP PF11559.8 KIY62982.1 - 0.66 10.0 13.5 1 9.4 8.5 2.6 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Hemerythrin PF01814.23 KIY62982.1 - 0.79 10.3 6.7 1.5 9.4 6.6 1.6 1 1 0 1 1 1 0 Hemerythrin HHE cation binding domain AAA_13 PF13166.6 KIY62982.1 - 0.93 8.1 4.9 1.3 7.6 4.9 1.2 1 0 0 1 1 1 0 AAA domain UPF0242 PF06785.11 KIY62982.1 - 0.94 9.6 9.6 10 6.2 7.9 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF4201 PF13870.6 KIY62982.1 - 1 9.1 13.1 29 4.3 13.1 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) JIP_LZII PF16471.5 KIY62982.1 - 1.1 9.5 9.3 9.4 6.5 0.7 3.4 2 1 1 3 3 3 0 JNK-interacting protein leucine zipper II TMPIT PF07851.13 KIY62982.1 - 1.3 8.2 4.5 1.5 7.9 4.1 1.3 1 1 0 1 1 1 0 TMPIT-like protein BST2 PF16716.5 KIY62982.1 - 1.3 9.7 14.0 1.4 9.5 6.0 3.4 2 1 2 4 4 2 0 Bone marrow stromal antigen 2 PspA_IM30 PF04012.12 KIY62982.1 - 1.5 8.4 15.2 2.2 7.8 13.5 1.8 1 1 1 2 2 2 0 PspA/IM30 family TMCO5 PF14992.6 KIY62982.1 - 1.5 8.3 5.2 1.8 8.1 5.2 1.1 1 0 0 1 1 1 0 TMCO5 family Phlebovirus_NSM PF07246.11 KIY62982.1 - 1.5 8.1 5.5 2.9 7.2 5.2 1.6 1 1 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Golgin_A5 PF09787.9 KIY62982.1 - 1.5 8.2 11.6 1.8 8.0 10.2 1.5 1 1 0 1 1 1 0 Golgin subfamily A member 5 Yuri_gagarin PF15934.5 KIY62982.1 - 1.6 8.5 8.9 4.4 7.1 8.9 1.6 1 1 0 1 1 1 0 Yuri gagarin CENP-Q PF13094.6 KIY62982.1 - 1.8 8.7 14.5 4.5 7.4 14.1 2.0 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit HALZ PF02183.18 KIY62982.1 - 1.9 8.8 12.8 0.47 10.7 0.3 3.5 4 0 0 4 4 3 0 Homeobox associated leucine zipper Cep57_CLD_2 PF14197.6 KIY62982.1 - 2.3 8.4 16.5 1.2e+02 2.9 16.5 3.2 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 BRE1 PF08647.11 KIY62982.1 - 3.2 7.9 10.3 1.3 9.1 0.8 2.3 1 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF2968 PF11180.8 KIY62982.1 - 3.4 7.3 13.1 1.8 8.2 10.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2968) HAUS-augmin3 PF14932.6 KIY62982.1 - 3.8 7.0 12.1 0.72 9.4 1.5 2.0 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 TMF_DNA_bd PF12329.8 KIY62982.1 - 4.7 7.3 12.6 1.6 8.8 5.3 2.8 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Csm1_N PF18504.1 KIY62982.1 - 5.1 7.5 10.5 7.5 7.0 0.5 3.2 1 1 3 4 4 4 0 Csm1 N-terminal domain Atg14 PF10186.9 KIY62982.1 - 5.3 6.0 13.2 4.6 6.2 10.9 1.5 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Prefoldin_2 PF01920.20 KIY62982.1 - 7 6.7 10.1 5.1 7.1 0.9 2.6 1 1 1 2 2 2 0 Prefoldin subunit TPD52 PF04201.15 KIY62982.1 - 7.7 6.1 9.5 42 3.7 0.2 3.1 1 1 2 3 3 3 0 Tumour protein D52 family Jnk-SapK_ap_N PF09744.9 KIY62982.1 - 9.4 6.4 13.7 16 5.7 13.7 1.5 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 p450 PF00067.22 KIY62983.1 - 3.5e-64 217.3 0.0 6.1e-64 216.5 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KIY62984.1 - 5e-68 229.9 0.0 1e-67 228.9 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 DUF3390 PF11870.8 KIY62985.1 - 0.056 13.8 0.5 0.12 12.8 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3390) Pap_E4 PF02711.14 KIY62985.1 - 1.4 9.9 5.0 0.32 12.0 1.6 1.7 2 0 0 2 2 2 0 E4 protein Pkinase PF00069.25 KIY62986.1 - 3e-56 190.7 0.0 4.1e-56 190.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY62986.1 - 7.6e-24 84.4 0.0 1.1e-23 83.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY62986.1 - 2e-05 24.1 0.1 6.1e-05 22.5 0.1 1.8 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 KIY62986.1 - 0.042 13.2 0.0 0.078 12.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KIY62986.1 - 0.15 11.7 0.0 18 4.9 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF3390 PF11870.8 KIY62987.1 - 0.059 13.8 0.4 0.11 12.8 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3390) Pap_E4 PF02711.14 KIY62987.1 - 3.6 8.6 7.1 0.3 12.1 1.8 1.8 2 0 0 2 2 2 0 E4 protein DUF842 PF05811.13 KIY62989.1 - 0.0025 17.5 0.2 0.0033 17.1 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) zf-H2C2_5 PF13909.6 KIY62989.1 - 0.019 14.7 0.0 0.066 13.0 0.0 1.9 1 0 0 1 1 1 0 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 KIY62989.1 - 0.22 12.5 3.7 2.6 9.1 0.0 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KIY62989.1 - 0.22 12.0 3.7 12 6.6 1.9 2.8 2 1 0 2 2 2 0 Zinc finger, C2H2 type Fructosamin_kin PF03881.14 KIY62992.1 - 0.059 12.6 0.0 0.087 12.0 0.0 1.1 1 0 0 1 1 1 0 Fructosamine kinase Cytochrom_C PF00034.21 KIY62993.1 - 1.3e-10 42.3 0.1 2.1e-10 41.6 0.1 1.3 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 KIY62993.1 - 3e-07 30.7 5.1 2.8e-06 27.5 5.1 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 KIY62993.1 - 0.0011 18.6 1.3 0.0039 16.9 0.2 2.1 2 1 0 2 2 2 1 Cytochrome c-550 domain Pkinase PF00069.25 KIY62999.1 - 2.6e-18 66.3 0.1 2.8e-18 66.2 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY62999.1 - 1.9e-13 50.3 0.1 2e-13 50.3 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KIY62999.1 - 2e-05 23.7 0.2 2.1e-05 23.6 0.2 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KIY62999.1 - 0.0013 18.2 0.0 0.0013 18.1 0.0 1.0 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KIY62999.1 - 0.014 14.2 0.1 0.014 14.2 0.1 1.1 1 0 0 1 1 1 0 Fungal protein kinase Seadorna_VP7 PF07387.11 KIY62999.1 - 0.024 13.7 0.1 0.028 13.5 0.1 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.22 KIY62999.1 - 0.037 13.6 0.1 0.044 13.4 0.1 1.1 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 KIY62999.1 - 0.042 13.8 0.4 0.046 13.6 0.4 1.3 1 1 0 1 1 1 0 Phosphotransferase enzyme family p47_phox_C PF08944.11 KIY62999.1 - 0.09 12.2 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 NADPH oxidase subunit p47Phox, C terminal domain Phage_holin_5_2 PF16079.5 KIY63000.1 - 3 8.3 4.4 20 5.6 0.1 2.9 3 0 0 3 3 3 0 Phage holin family Hol44, in holin superfamily V Goodbye PF17109.5 KIY63001.1 - 0.00037 20.9 0.0 0.00091 19.7 0.0 1.7 1 0 0 1 1 1 1 fungal STAND N-terminal Goodbye domain Adeno_E3_CR2 PF02439.15 KIY63002.1 - 0.0035 17.1 3.7 0.0073 16.0 3.7 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 EphA2_TM PF14575.6 KIY63002.1 - 0.052 14.4 0.0 0.098 13.5 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Amnionless PF14828.6 KIY63002.1 - 0.22 10.3 0.0 0.25 10.1 0.0 1.1 1 0 0 1 1 1 0 Amnionless TPP_enzyme_N PF02776.18 KIY63003.1 - 1.9e-34 118.7 0.1 3.1e-34 118.1 0.1 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KIY63003.1 - 3.5e-10 39.9 0.1 2e-09 37.4 0.1 2.1 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KIY63003.1 - 1.2e-05 25.1 0.0 0.00014 21.6 0.0 2.7 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain Forkhead PF00250.18 KIY63005.1 - 1e-15 57.7 0.0 1.2e-15 57.5 0.0 1.0 1 0 0 1 1 1 1 Forkhead domain Lipase_GDSL_2 PF13472.6 KIY63006.1 - 1.4e-11 45.1 0.6 1.7e-11 44.8 0.6 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KIY63006.1 - 1.3e-07 31.8 0.1 1.9e-07 31.3 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase ALGX PF16822.5 KIY63006.1 - 0.0011 18.7 0.1 0.021 14.5 0.0 2.2 2 1 0 2 2 2 1 SGNH hydrolase-like domain, acetyltransferase AlgX DUF1330 PF07045.11 KIY63006.1 - 0.036 14.4 0.0 8.6 6.8 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1330) Piwi PF02171.17 KIY63007.1 - 4e-70 236.4 0.0 5.6e-70 236.0 0.0 1.1 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 KIY63007.1 - 1.6e-18 67.6 0.8 4.1e-18 66.3 0.1 2.1 3 0 0 3 3 3 1 N-terminal domain of argonaute ArgoL1 PF08699.10 KIY63007.1 - 3.7e-15 55.3 0.0 8.8e-15 54.1 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain PAZ PF02170.22 KIY63007.1 - 3.1e-11 43.2 0.0 5.9e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 PAZ domain ArgoL2 PF16488.5 KIY63007.1 - 7.9e-06 26.1 0.0 0.00027 21.2 0.0 3.0 2 0 0 2 2 2 1 Argonaute linker 2 domain ArgoMid PF16487.5 KIY63007.1 - 0.00089 19.5 0.0 0.0019 18.4 0.0 1.5 1 0 0 1 1 1 1 Mid domain of argonaute DTHCT PF08070.11 KIY63010.1 - 0.011 16.5 8.5 0.023 15.4 8.5 1.6 1 0 0 1 1 1 0 DTHCT (NUC029) region PROL5-SMR PF15621.6 KIY63010.1 - 2.4 8.7 6.6 0.76 10.3 1.4 2.3 2 0 0 2 2 2 0 Proline-rich submaxillary gland androgen-regulated family DTHCT PF08070.11 KIY63011.1 - 0.051 14.3 3.2 0.16 12.7 3.2 1.8 1 0 0 1 1 1 0 DTHCT (NUC029) region SCP2_2 PF13530.6 KIY63015.1 - 0.11 12.9 0.0 0.23 11.9 0.0 1.5 1 0 0 1 1 1 0 Sterol carrier protein domain LRR_4 PF12799.7 KIY63016.1 - 0.043 14.3 0.0 0.75 10.3 0.0 2.8 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) DUF961 PF06125.11 KIY63017.1 - 0.05 14.0 0.0 0.097 13.0 0.0 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF961) DUF1543 PF07566.12 KIY63017.1 - 0.16 11.8 0.0 2 8.2 0.1 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1543) Polysacc_deac_1 PF01522.21 KIY63018.1 - 5.4e-27 94.2 0.0 1.1e-26 93.2 0.0 1.5 1 1 1 2 2 2 1 Polysaccharide deacetylase F-box-like PF12937.7 KIY63020.1 - 0.0005 19.9 3.6 0.00062 19.6 2.0 2.1 2 0 0 2 2 2 1 F-box-like FAD_binding_4 PF01565.23 KIY63021.1 - 2.7e-17 62.8 0.0 3.7e-17 62.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KIY63021.1 - 0.053 13.6 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Berberine and berberine like Zn_clus PF00172.18 KIY63022.1 - 0.0013 18.8 16.0 0.07 13.3 7.5 2.4 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain SF1-HH PF16275.5 KIY63022.1 - 0.071 13.5 0.2 0.15 12.4 0.2 1.5 1 0 0 1 1 1 0 Splicing factor 1 helix-hairpin domain zf-CCCH_4 PF18044.1 KIY63023.1 - 4.8e-08 32.6 13.5 0.00038 20.2 3.2 2.5 2 0 0 2 2 2 2 CCCH-type zinc finger Ank_2 PF12796.7 KIY63023.1 - 8e-08 32.8 0.4 1.8e-07 31.7 0.1 1.7 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Torus PF16131.5 KIY63023.1 - 6.2e-06 26.9 2.2 0.00019 22.1 0.0 2.3 2 0 0 2 2 2 1 Torus domain zf_CCCH_4 PF18345.1 KIY63023.1 - 8.5e-06 25.6 13.4 0.0002 21.3 1.5 2.8 3 0 0 3 3 3 2 Zinc finger domain Ank_3 PF13606.6 KIY63023.1 - 1.4e-05 25.0 0.2 0.0021 18.4 0.0 3.8 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.6 KIY63023.1 - 1.8e-05 25.2 0.0 4.5e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) zf-CCCH_2 PF14608.6 KIY63023.1 - 2e-05 24.9 7.1 2e-05 24.9 7.1 2.5 2 0 0 2 2 2 1 RNA-binding, Nab2-type zinc finger Ank_5 PF13857.6 KIY63023.1 - 0.0029 17.9 0.0 0.39 11.1 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) zf-CCCH PF00642.24 KIY63023.1 - 0.0034 17.3 10.3 0.15 12.0 0.9 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Ank PF00023.30 KIY63023.1 - 0.0035 17.7 0.2 0.086 13.3 0.1 2.6 2 0 0 2 2 2 1 Ankyrin repeat NAD_Gly3P_dh_C PF07479.14 KIY63024.1 - 5.8e-49 166.0 0.4 8.6e-49 165.5 0.4 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 KIY63024.1 - 5.5e-33 114.2 0.0 1e-32 113.3 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 KIY63024.1 - 6.3e-07 29.2 0.0 1e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 KIY63024.1 - 3.9e-05 24.2 0.0 0.00015 22.3 0.0 2.0 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Pyr_redox PF00070.27 KIY63024.1 - 0.0016 19.0 0.1 1.2 9.7 0.0 3.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_2 PF03446.15 KIY63024.1 - 0.0045 17.2 0.0 0.015 15.5 0.0 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 KIY63024.1 - 0.038 14.1 0.0 0.12 12.5 0.0 1.9 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox_2 PF07992.14 KIY63024.1 - 0.039 13.2 0.0 0.23 10.6 0.0 2.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase SNARE PF05739.19 KIY63025.1 - 5.5e-14 51.9 0.1 1.4e-13 50.6 0.1 1.8 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 KIY63025.1 - 5.3e-06 26.3 15.5 0.0001 22.1 1.8 2.5 2 1 0 2 2 2 2 Syntaxin Syntaxin-5_N PF11416.8 KIY63025.1 - 8.6e-05 21.6 0.6 0.00028 20.0 0.2 2.2 2 0 0 2 2 2 1 Syntaxin-5 N-terminal, Sly1p-binding domain Syntaxin-18_N PF10496.9 KIY63025.1 - 0.0026 18.0 0.9 0.0026 18.0 0.9 3.3 3 1 0 3 3 3 1 SNARE-complex protein Syntaxin-18 N-terminus BLOC1_2 PF10046.9 KIY63025.1 - 0.0077 16.5 9.6 0.31 11.3 1.5 2.8 2 0 0 2 2 2 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 SlyX PF04102.12 KIY63025.1 - 0.042 14.5 9.9 0.63 10.7 1.0 3.4 3 0 0 3 3 3 0 SlyX DUF2313 PF10076.9 KIY63025.1 - 0.07 13.0 1.2 0.14 12.0 0.1 2.0 2 1 0 2 2 2 0 Uncharacterised protein conserved in bacteria (DUF2313) FlaC_arch PF05377.11 KIY63025.1 - 0.35 11.3 5.0 12 6.4 0.1 3.7 2 2 2 4 4 4 0 Flagella accessory protein C (FlaC) SKA1 PF07160.12 KIY63025.1 - 0.78 9.5 12.2 3.4 7.5 5.1 2.4 2 1 0 2 2 2 0 Spindle and kinetochore-associated protein 1 DUF16 PF01519.16 KIY63025.1 - 0.98 9.9 8.6 0.86 10.1 0.7 2.5 2 0 0 2 2 2 0 Protein of unknown function DUF16 NPV_P10 PF05531.12 KIY63025.1 - 2.4 8.7 9.4 1.4 9.4 1.3 3.0 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Spectrin PF00435.21 KIY63025.1 - 2.7 8.5 8.8 5.4 7.6 1.3 2.6 2 1 0 2 2 2 0 Spectrin repeat DUF1664 PF07889.12 KIY63025.1 - 2.9 8.0 11.1 3.3 7.8 0.9 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) ISG65-75 PF11727.8 KIY63025.1 - 3.1 6.9 6.8 7.1 5.8 0.1 2.1 2 0 0 2 2 2 0 Invariant surface glycoprotein End3 PF12761.7 KIY63025.1 - 3.4 7.8 10.4 0.36 11.0 1.4 2.6 2 1 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 Pheromone PF08015.11 KIY63025.1 - 4.8 8.3 7.9 1.7 9.8 1.1 2.8 2 1 1 3 3 3 0 Fungal mating-type pheromone RRM_1 PF00076.22 KIY63026.1 - 2e-09 37.1 0.0 4.7e-09 35.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-U1 PF06220.12 KIY63026.1 - 0.068 12.9 0.2 0.14 12.0 0.2 1.5 1 0 0 1 1 1 0 U1 zinc finger F-box-like PF12937.7 KIY63027.1 - 1.3e-05 25.0 1.8 3.4e-05 23.7 0.5 2.3 2 0 0 2 2 2 1 F-box-like ANAPC5 PF12862.7 KIY63028.1 - 3.7e-08 33.3 2.7 8.5e-07 29.0 0.4 3.2 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 5 TPR_14 PF13428.6 KIY63028.1 - 0.089 13.7 5.5 3.4 8.7 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 KIY63028.1 - 0.63 10.0 8.8 3 7.8 0.7 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat BCL_N PF04714.13 KIY63029.1 - 0.00043 20.3 0.0 0.00073 19.5 0.0 1.3 1 0 0 1 1 1 1 BCL7, N-terminal conserver region Med7 PF05983.11 KIY63030.1 - 4e-47 160.8 0.3 5e-47 160.5 0.3 1.1 1 0 0 1 1 1 1 MED7 protein AMP-binding PF00501.28 KIY63031.1 - 1e-87 294.5 0.0 1.3e-87 294.2 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KIY63031.1 - 2e-16 60.7 0.3 1.4e-15 58.0 0.0 2.6 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain Rep_fac_C PF08542.11 KIY63032.1 - 1.7e-24 86.0 0.0 3.6e-24 85.0 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 KIY63032.1 - 7.5e-13 48.6 0.1 1.7e-10 40.9 0.1 2.2 1 1 1 2 2 2 1 DNA polymerase III, delta subunit AAA PF00004.29 KIY63032.1 - 5e-12 46.4 0.1 9e-12 45.6 0.1 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KIY63032.1 - 5.6e-07 29.6 0.0 1e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KIY63032.1 - 7.5e-07 29.7 0.0 4.7e-05 23.8 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KIY63032.1 - 3.6e-06 27.3 0.0 0.0034 17.7 0.0 2.3 1 1 1 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 KIY63032.1 - 2e-05 24.4 0.0 3.2e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase RuvB_N PF05496.12 KIY63032.1 - 2.8e-05 23.9 0.0 7e-05 22.6 0.0 1.7 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 KIY63032.1 - 3.3e-05 23.8 0.0 6.2e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta PF06144.13 KIY63032.1 - 0.00027 20.8 0.0 0.00041 20.2 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Mg_chelatase PF01078.21 KIY63032.1 - 0.00087 18.7 0.0 0.011 15.1 0.0 2.2 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI MeaB PF03308.16 KIY63032.1 - 0.0021 17.1 0.0 0.0055 15.7 0.0 1.7 1 1 1 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Rad17 PF03215.15 KIY63032.1 - 0.0021 18.0 0.0 0.0039 17.1 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_assoc_2 PF16193.5 KIY63032.1 - 0.0048 17.2 0.1 0.013 15.8 0.0 1.8 2 0 0 2 2 1 1 AAA C-terminal domain NTPase_1 PF03266.15 KIY63032.1 - 0.006 16.5 0.2 0.016 15.1 0.1 1.8 1 1 1 2 2 2 1 NTPase AAA_24 PF13479.6 KIY63032.1 - 0.0073 16.0 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KIY63032.1 - 0.0083 15.9 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KIY63032.1 - 0.02 15.3 0.1 0.093 13.1 0.1 2.2 1 1 0 1 1 1 0 RNA helicase TniB PF05621.11 KIY63032.1 - 0.035 13.5 0.0 3.1 7.2 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein AAA_19 PF13245.6 KIY63032.1 - 0.042 14.2 0.4 0.19 12.1 0.4 2.1 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KIY63032.1 - 0.045 13.8 0.1 0.14 12.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 KIY63032.1 - 0.094 12.4 0.1 0.2 11.3 0.1 1.6 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.22 KIY63032.1 - 0.095 12.3 0.1 0.22 11.1 0.0 1.5 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain ABC_tran PF00005.27 KIY63032.1 - 0.11 13.1 0.1 0.29 11.6 0.1 1.7 1 1 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 KIY63032.1 - 0.11 13.0 0.1 0.23 12.0 0.1 1.6 1 1 0 1 1 1 0 AAA domain DEAD PF00270.29 KIY63032.1 - 0.14 12.0 0.1 0.94 9.2 0.1 2.1 1 1 1 2 2 2 0 DEAD/DEAH box helicase KTI12 PF08433.10 KIY63032.1 - 0.16 11.4 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 tRNA-synt_2b PF00587.25 KIY63033.1 - 5.6e-27 94.9 0.0 1.1e-26 93.9 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 KIY63033.1 - 1.5e-05 25.2 3.4 1.5e-05 25.2 3.4 1.9 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain VHS PF00790.19 KIY63034.1 - 4.4e-27 94.7 0.0 8.1e-27 93.8 0.0 1.5 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 KIY63034.1 - 9.4e-08 32.3 0.9 2.7e-07 30.8 0.9 1.9 1 0 0 1 1 1 1 GAT domain DUF4253 PF14062.6 KIY63034.1 - 0.11 12.7 0.0 0.44 10.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4253) Pet100 PF09803.9 KIY63034.1 - 0.19 12.2 1.3 0.6 10.7 1.3 1.9 1 0 0 1 1 1 0 Pet100 Utp11 PF03998.13 KIY63035.1 - 1.3e-72 244.7 15.3 1.6e-72 244.4 15.3 1.1 1 0 0 1 1 1 1 Utp11 protein SLATT_5 PF18160.1 KIY63035.1 - 0.028 13.8 0.8 0.047 13.0 0.8 1.3 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 Acetyltransf_1 PF00583.25 KIY63037.1 - 6.3e-09 36.1 0.1 9.1e-09 35.6 0.1 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KIY63037.1 - 0.00012 22.0 0.0 0.00023 21.1 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 KIY63037.1 - 0.00013 22.3 0.1 0.0002 21.7 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KIY63037.1 - 0.001 19.2 0.0 0.0016 18.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KIY63037.1 - 0.0014 19.3 0.0 0.0017 19.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KIY63037.1 - 0.12 12.3 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain UPF0227 PF05728.12 KIY63038.1 - 0.043 13.7 0.0 0.085 12.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) FAD_oxidored PF12831.7 KIY63038.1 - 0.044 13.1 0.0 0.06 12.7 0.0 1.3 1 1 0 1 1 1 0 FAD dependent oxidoreductase PH PF00169.29 KIY63039.1 - 1.4e-06 28.8 1.6 3.1e-06 27.7 1.6 1.5 1 1 0 1 1 1 1 PH domain SRP-alpha_N PF04086.13 KIY63041.1 - 4.1e-08 33.5 0.0 5.3e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal Plavaka PF18759.1 KIY63045.1 - 5.2e-97 325.0 0.2 2.7e-78 263.4 0.0 2.2 1 1 1 2 2 2 2 Plavaka transposase DUF5523 PF17661.1 KIY63045.1 - 0.13 11.9 4.4 0.23 11.1 4.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5523) DNA_pol_phi PF04931.13 KIY63045.1 - 1.1 7.3 13.5 1.8 6.6 13.5 1.3 1 0 0 1 1 1 0 DNA polymerase phi SDA1 PF05285.12 KIY63045.1 - 2 7.8 7.8 3.4 7.0 7.8 1.3 1 0 0 1 1 1 0 SDA1 Ubiquitin_3 PF14836.6 KIY63046.1 - 0.096 12.7 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-like domain KDZ PF18758.1 KIY63047.1 - 1.3e-30 106.7 0.0 1.4e-30 106.5 0.0 1.0 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase mRNA_cap_enzyme PF01331.19 KIY63048.1 - 3e-46 157.7 0.0 4e-46 157.3 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 KIY63048.1 - 1.1e-31 109.7 0.0 1.8e-31 108.9 0.0 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 KIY63048.1 - 1.3e-09 38.1 0.0 1.6e-05 24.6 0.0 2.3 1 1 1 2 2 2 2 ATP dependent DNA ligase domain Skp1 PF01466.19 KIY63049.1 - 2.8e-29 101.0 0.5 4.7e-29 100.2 0.5 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 KIY63049.1 - 6.1e-24 84.0 0.9 1.5e-23 82.7 0.1 2.1 3 0 0 3 3 3 1 Skp1 family, tetramerisation domain BTB PF00651.31 KIY63049.1 - 0.001 19.3 0.0 0.1 12.9 0.0 2.2 2 0 0 2 2 2 2 BTB/POZ domain DUF615 PF04751.14 KIY63049.1 - 0.084 12.9 0.1 0.17 11.9 0.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF615) Ribosomal_L27 PF01016.19 KIY63050.1 - 7.7e-33 112.4 0.5 1.4e-32 111.5 0.5 1.4 1 0 0 1 1 1 1 Ribosomal L27 protein DUF3074 PF11274.8 KIY63051.1 - 6.6e-41 140.3 0.1 8.3e-41 140.0 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) START PF01852.19 KIY63051.1 - 0.0033 16.9 0.0 0.0068 15.8 0.0 1.5 1 1 1 2 2 2 1 START domain MAP65_ASE1 PF03999.12 KIY63052.1 - 0.35 9.5 0.9 0.54 8.9 0.9 1.3 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Amidohydro_1 PF01979.20 KIY63053.1 - 1.7e-66 224.9 0.0 2.1e-66 224.6 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KIY63053.1 - 6.6e-07 29.2 0.1 0.00082 19.0 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family A_deaminase PF00962.22 KIY63053.1 - 4.2e-05 23.0 0.0 6.5e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase Lipase_3 PF01764.25 KIY63054.1 - 1.6e-06 28.1 0.0 2.7e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KIY63054.1 - 0.0035 18.0 0.9 0.005 17.5 0.1 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family UPF0227 PF05728.12 KIY63054.1 - 0.0082 16.1 0.1 0.014 15.3 0.1 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) Abhydrolase_1 PF00561.20 KIY63054.1 - 0.047 13.3 0.1 0.078 12.6 0.1 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold ABC_membrane PF00664.23 KIY63055.1 - 7.8e-36 124.1 12.0 9.8e-36 123.8 12.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KIY63055.1 - 1.1e-32 113.4 0.0 3.5e-32 111.8 0.0 1.8 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 KIY63055.1 - 0.00059 19.3 2.8 0.0064 16.0 0.3 2.5 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_5 PF07728.14 KIY63055.1 - 0.022 14.7 0.0 0.12 12.3 0.0 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.29 KIY63055.1 - 0.023 15.1 0.2 0.42 11.0 0.2 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KIY63055.1 - 0.025 15.0 0.0 0.08 13.3 0.0 2.0 2 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 KIY63055.1 - 0.03 14.6 0.0 0.25 11.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 KIY63055.1 - 0.043 13.0 0.0 0.095 11.8 0.0 1.5 1 0 0 1 1 1 0 G-protein alpha subunit RsgA_GTPase PF03193.16 KIY63055.1 - 0.056 13.3 0.0 0.2 11.5 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase AAA_15 PF13175.6 KIY63055.1 - 0.073 12.8 0.1 0.26 10.9 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.6 KIY63055.1 - 0.084 13.0 0.2 0.5 10.5 0.0 2.3 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KIY63055.1 - 0.098 12.7 0.0 0.34 11.0 0.0 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.6 KIY63055.1 - 0.1 12.4 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 KIY63055.1 - 0.12 11.9 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_21 PF13304.6 KIY63055.1 - 0.13 12.0 0.0 1.1 9.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 KIY63055.1 - 0.21 11.8 2.7 0.69 10.2 0.6 2.6 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Gln-synt_C PF00120.24 KIY63056.1 - 6.5e-76 255.6 0.0 7.9e-76 255.3 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain WD40 PF00400.32 KIY63057.1 - 1.2e-05 26.0 0.0 1.1 10.3 0.0 4.3 3 0 0 3 3 3 2 WD domain, G-beta repeat PQQ_3 PF13570.6 KIY63057.1 - 0.003 18.0 5.1 0.32 11.6 0.1 4.1 5 0 0 5 5 5 2 PQQ-like domain DNA_pol3_beta PF00712.19 KIY63057.1 - 0.14 12.3 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase III beta subunit, N-terminal domain Peptidase_S10 PF00450.22 KIY63058.1 - 2e-113 379.9 0.0 2.6e-113 379.6 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Fungal_trans PF04082.18 KIY63059.1 - 4.3e-22 78.4 0.1 9.4e-22 77.3 0.1 1.5 1 1 1 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY63059.1 - 9.9e-10 38.4 3.3 2.2e-09 37.3 3.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain APS_kinase PF01583.20 KIY63060.1 - 1.6e-71 239.3 0.0 2e-71 239.0 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 KIY63060.1 - 1.6e-05 25.1 0.0 3.1e-05 24.2 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KIY63060.1 - 0.0002 21.9 0.0 0.00032 21.3 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KIY63060.1 - 0.0082 15.9 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain KTI12 PF08433.10 KIY63060.1 - 0.015 14.8 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 G-alpha PF00503.20 KIY63060.1 - 0.026 13.7 0.1 0.044 12.9 0.1 1.3 1 0 0 1 1 1 0 G-protein alpha subunit CPT PF07931.12 KIY63060.1 - 0.061 13.2 0.2 0.27 11.1 0.2 2.0 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein ABC_tran PF00005.27 KIY63060.1 - 0.15 12.6 0.0 0.17 12.4 0.0 1.3 1 0 0 1 1 1 0 ABC transporter Trehalase_Ca-bi PF07492.11 KIY63061.1 - 2.7e-09 36.6 0.0 5.2e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain SCP2 PF02036.17 KIY63061.1 - 0.18 12.3 0.0 0.27 11.7 0.0 1.2 1 0 0 1 1 1 0 SCP-2 sterol transfer family p450 PF00067.22 KIY63062.1 - 1.6e-10 40.3 0.0 2.1e-10 40.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MLIP PF15274.6 KIY63063.1 - 0.012 15.6 0.5 0.027 14.4 0.5 1.5 1 0 0 1 1 1 0 Muscular LMNA-interacting protein PARP PF00644.20 KIY63064.1 - 6.8e-57 192.2 2.6 7e-57 192.2 0.0 2.2 2 1 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 KIY63064.1 - 2.9e-38 131.0 0.0 4.4e-38 130.4 0.0 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 KIY63064.1 - 8.2e-20 70.7 0.0 2.9e-19 68.9 0.0 2.0 1 0 0 1 1 1 1 WGR domain DUF3246 PF11596.8 KIY63064.1 - 0.41 10.0 2.0 0.89 8.9 2.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Ndc1_Nup PF09531.10 KIY63064.1 - 0.53 8.9 11.7 0.8 8.3 11.7 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup p450 PF00067.22 KIY63065.1 - 4.7e-68 230.0 0.0 1.2e-67 228.7 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 NTP_transf_3 PF12804.7 KIY63067.1 - 8.7e-10 39.2 0.2 1.9e-09 38.1 0.2 1.6 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.24 KIY63067.1 - 7.3e-09 35.0 2.3 0.0008 19.0 0.4 3.7 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.23 KIY63067.1 - 1.1e-06 28.4 0.0 2.1e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase DUF4954 PF16314.5 KIY63067.1 - 0.00038 18.7 0.5 0.00053 18.3 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) Fucokinase PF07959.12 KIY63067.1 - 0.15 10.9 0.4 6.3 5.6 0.1 2.1 1 1 1 2 2 2 0 L-fucokinase MFS_1 PF07690.16 KIY63068.1 - 4.9e-14 52.0 30.7 4.9e-14 52.0 30.7 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Cullin PF00888.22 KIY63069.1 - 7.9e-06 24.8 0.0 1.1e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Cullin family TRAPP PF04051.16 KIY63071.1 - 9.9e-40 135.6 0.0 1.2e-39 135.4 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component BTB PF00651.31 KIY63072.1 - 0.00051 20.2 0.0 0.00064 19.9 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain DUF4148 PF13663.6 KIY63072.1 - 0.035 14.3 0.0 0.08 13.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) MS_channel PF00924.18 KIY63075.1 - 2.9e-21 76.0 0.4 5.4e-21 75.1 0.4 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 KIY63075.1 - 0.00025 20.4 0.1 0.00054 19.3 0.1 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KIY63075.1 - 0.004 17.0 0.0 0.012 15.5 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 KIY63075.1 - 0.091 12.3 0.1 0.27 10.8 0.0 1.9 2 0 0 2 2 2 0 EF hand EF-hand_7 PF13499.6 KIY63075.1 - 0.092 13.2 0.0 0.29 11.6 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain pair JAB PF01398.21 KIY63078.1 - 1.7e-23 82.8 0.0 2.7e-23 82.2 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 KIY63078.1 - 8.3e-14 52.0 0.0 1.4e-13 51.2 0.0 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Tom7 PF08038.12 KIY63079.1 - 7.2e-20 70.4 0.1 8.1e-20 70.2 0.1 1.0 1 0 0 1 1 1 1 TOM7 family Ornatin PF02088.15 KIY63080.1 - 0.061 13.1 0.3 0.096 12.5 0.3 1.3 1 0 0 1 1 1 0 Ornatin Aminotran_5 PF00266.19 KIY63081.1 - 1.7e-13 50.3 0.0 7.7e-07 28.4 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V Aminotran_1_2 PF00155.21 KIY63081.1 - 0.0012 18.1 0.0 0.0021 17.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KIY63081.1 - 0.0012 18.3 0.4 0.019 14.3 0.0 2.1 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family DAO PF01266.24 KIY63084.1 - 2e-30 106.6 0.1 3.1e-30 105.9 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIY63084.1 - 3.8e-05 23.1 0.0 0.00089 18.6 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIY63084.1 - 0.0078 16.4 0.0 0.019 15.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Sacchrp_dh_NADP PF03435.18 KIY63084.1 - 0.018 15.3 0.0 0.052 13.8 0.0 1.7 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_9 PF13454.6 KIY63084.1 - 0.02 14.9 0.0 0.037 14.0 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KIY63084.1 - 0.025 13.7 0.1 0.12 11.5 0.1 2.0 1 1 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 KIY63084.1 - 0.068 12.2 0.1 0.12 11.5 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.17 KIY63084.1 - 0.15 11.3 0.0 0.32 10.2 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 KIY63084.1 - 0.22 10.7 0.0 15 4.7 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GST_N_3 PF13417.6 KIY63085.1 - 1.6e-12 47.6 0.1 2.5e-12 47.0 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KIY63085.1 - 8.5e-08 32.4 0.0 1.3e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KIY63085.1 - 1.7e-07 31.4 0.1 4.4e-07 30.1 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 KIY63085.1 - 3.1e-05 24.1 0.0 0.00016 21.8 0.0 2.0 2 0 0 2 2 2 1 Glutaredoxin GST_C_2 PF13410.6 KIY63085.1 - 5.4e-05 23.1 1.1 0.0001 22.3 1.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KIY63085.1 - 0.0022 18.2 0.2 0.012 15.8 0.1 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KIY63085.1 - 0.082 13.5 0.0 0.15 12.6 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain ThrE PF06738.12 KIY63086.1 - 1e-53 182.2 8.1 1e-53 182.2 8.1 2.3 2 0 0 2 2 2 1 Putative threonine/serine exporter ThrE_2 PF12821.7 KIY63086.1 - 7e-07 29.4 9.9 7e-07 29.4 9.9 2.5 2 0 0 2 2 2 1 Threonine/Serine exporter, ThrE NmrA PF05368.13 KIY63090.1 - 3.1e-08 33.5 0.1 4.8e-08 32.8 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KIY63090.1 - 1.1e-07 31.9 0.5 1.7e-07 31.3 0.5 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KIY63090.1 - 1.5e-05 24.4 0.0 3.1e-05 23.3 0.0 1.6 2 0 0 2 2 2 1 Male sterility protein TrkA_N PF02254.18 KIY63090.1 - 7e-05 23.1 0.2 0.00013 22.2 0.2 1.4 1 0 0 1 1 1 1 TrkA-N domain Epimerase PF01370.21 KIY63090.1 - 0.00063 19.3 0.1 0.015 14.8 0.1 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KIY63090.1 - 0.0091 15.0 0.0 0.016 14.2 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 KIY63090.1 - 0.023 15.1 0.1 0.042 14.3 0.1 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain F-box-like PF12937.7 KIY63091.1 - 9.7e-10 38.2 0.0 2.5e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY63091.1 - 1.4e-06 28.0 0.1 4.4e-06 26.4 0.1 1.9 1 0 0 1 1 1 1 F-box domain PRIMA1 PF16101.5 KIY63091.1 - 0.0037 17.3 0.6 0.0068 16.4 0.6 1.4 1 0 0 1 1 1 1 Proline-rich membrane anchor 1 F-box_4 PF15966.5 KIY63091.1 - 0.088 12.7 0.0 0.3 11.0 0.0 1.8 1 0 0 1 1 1 0 F-box PX PF00787.24 KIY63091.1 - 0.17 11.9 0.2 1 9.4 0.0 2.2 2 0 0 2 2 2 0 PX domain CAP_N PF01213.19 KIY63091.1 - 0.79 9.1 3.0 1.2 8.6 3.0 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Plavaka PF18759.1 KIY63093.1 - 3.2e-26 92.3 0.0 5.4e-26 91.6 0.0 1.3 1 0 0 1 1 1 1 Plavaka transposase BNR PF02012.20 KIY63093.1 - 0.63 10.3 4.4 0.17 12.0 0.2 2.4 2 0 0 2 2 2 0 BNR/Asp-box repeat Perilipin PF03036.16 KIY63097.1 - 0.0076 15.3 0.4 0.014 14.5 0.4 1.3 1 0 0 1 1 1 1 Perilipin family SOGA PF11365.8 KIY63097.1 - 0.083 14.0 0.3 0.27 12.4 0.3 1.8 1 0 0 1 1 1 0 Protein SOGA SlyX PF04102.12 KIY63097.1 - 0.16 12.6 2.2 1 10.1 2.2 2.5 1 0 0 1 1 1 0 SlyX p450 PF00067.22 KIY63098.1 - 8.4e-58 196.2 0.0 2.7e-57 194.5 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 ADH_N PF08240.12 KIY63099.1 - 2.8e-28 97.9 1.1 4.7e-28 97.2 1.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KIY63099.1 - 1.4e-12 47.7 0.1 2.3e-12 47.0 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KIY63099.1 - 1.9e-05 25.7 0.0 4.7e-05 24.5 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KIY63099.1 - 0.0003 20.2 0.1 0.00051 19.5 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KIY63099.1 - 0.0028 17.0 0.0 0.0047 16.3 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain zf-NADH-PPase PF09297.11 KIY63099.1 - 0.042 13.5 0.1 0.042 13.5 0.1 2.1 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain p450 PF00067.22 KIY63100.1 - 3e-66 224.1 0.0 1.1e-65 222.2 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 GPI-anchored PF10342.9 KIY63101.1 - 1.3e-07 32.3 2.4 1.3e-07 32.3 2.4 2.1 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Amelotin PF15757.5 KIY63101.1 - 0.1 12.2 6.4 0.19 11.3 6.4 1.6 1 0 0 1 1 1 0 Amelotin Apt1 PF10351.9 KIY63101.1 - 1.4 7.7 6.3 1.7 7.4 6.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SPX PF03105.19 KIY63101.1 - 3.9 7.3 8.3 4.6 7.0 8.3 1.1 1 0 0 1 1 1 0 SPX domain Ycf66_N PF07444.11 KIY63103.1 - 0.012 15.7 0.7 0.024 14.8 0.0 1.9 2 0 0 2 2 2 0 Ycf66 protein N-terminus FliC_SP PF12613.8 KIY63107.1 - 0.39 11.2 2.0 0.81 10.2 2.0 1.6 1 0 0 1 1 1 0 Flagellin structural protein ubiquitin PF00240.23 KIY63108.1 - 4.6e-10 39.1 0.0 8.5e-10 38.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KIY63108.1 - 0.048 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like CD20 PF04103.15 KIY63109.1 - 0.0032 17.6 0.4 0.0078 16.3 0.4 1.6 1 0 0 1 1 1 1 CD20-like family ABC2_membrane PF01061.24 KIY63109.1 - 1.8 7.9 21.6 0.027 13.9 12.6 2.0 1 1 1 2 2 2 0 ABC-2 type transporter zf-MYND PF01753.18 KIY63114.1 - 1.7e-07 31.2 13.6 1.7e-07 31.2 13.6 2.5 2 1 0 2 2 2 1 MYND finger CoA_transf_3 PF02515.17 KIY63116.1 - 8.9e-69 232.3 0.0 1.1e-68 232.0 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III adh_short_C2 PF13561.6 KIY63118.1 - 7.2e-54 182.8 0.5 9.6e-54 182.4 0.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIY63118.1 - 9.8e-50 168.7 1.3 1.1e-49 168.5 1.3 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIY63118.1 - 4e-09 36.7 0.7 5.6e-09 36.2 0.7 1.2 1 0 0 1 1 1 1 KR domain Peripla_BP_6 PF13458.6 KIY63118.1 - 0.01 15.5 0.7 0.11 12.2 0.2 2.3 1 1 1 2 2 2 0 Periplasmic binding protein Metallophos_2 PF12850.7 KIY63118.1 - 0.012 15.8 0.0 0.017 15.3 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain 4HB_MCP_1 PF12729.7 KIY63118.1 - 0.035 13.7 0.1 0.1 12.1 0.0 1.6 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction 3HCDH_N PF02737.18 KIY63118.1 - 0.092 12.6 0.3 0.17 11.8 0.1 1.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 KIY63118.1 - 0.13 11.7 0.7 0.77 9.2 0.7 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family PA28_alpha PF02251.18 KIY63118.1 - 0.18 11.9 0.1 0.55 10.3 0.0 1.7 2 0 0 2 2 2 0 Proteasome activator pa28 alpha subunit Serendipity_A PF05482.12 KIY63118.1 - 0.2 10.2 0.1 0.26 9.9 0.1 1.1 1 0 0 1 1 1 0 Serendipity locus alpha protein (SRY-A) MRP-L47 PF06984.13 KIY63119.1 - 1e-21 76.8 0.2 2.2e-21 75.7 0.2 1.6 1 1 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Ribosomal_L29 PF00831.23 KIY63119.1 - 0.0022 17.9 1.1 0.015 15.3 1.1 2.4 1 1 0 1 1 1 1 Ribosomal L29 protein AAA_21 PF13304.6 KIY63120.1 - 7e-13 49.1 0.6 5.6e-05 23.1 0.0 3.5 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KIY63120.1 - 1.9e-12 48.1 122.3 8.4e-07 29.7 83.9 7.5 2 1 1 3 3 1 1 AAA domain AAA_15 PF13175.6 KIY63120.1 - 1.3e-11 44.9 0.1 1.3e-11 44.9 0.1 5.6 1 1 3 4 4 2 2 AAA ATPase domain SMC_N PF02463.19 KIY63120.1 - 5.2e-08 32.6 0.0 5.2e-08 32.6 0.0 3.9 3 1 0 3 3 2 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 KIY63120.1 - 1.8e-06 28.1 0.0 7.5e-06 26.1 0.0 2.1 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_13 PF13166.6 KIY63120.1 - 3.2e-06 26.1 15.7 0.00022 20.1 13.4 7.3 4 2 3 7 7 6 3 AAA domain Phage_GP20 PF06810.11 KIY63120.1 - 0.00027 20.8 5.6 0.00027 20.8 5.6 10.6 4 3 5 10 10 9 2 Phage minor structural protein GP20 AAA_29 PF13555.6 KIY63120.1 - 0.0018 18.0 0.0 0.0041 16.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 KIY63120.1 - 0.0074 16.8 0.0 0.0074 16.8 0.0 7.2 3 2 3 6 6 5 2 ABC transporter Roc PF08477.13 KIY63120.1 - 0.037 14.2 0.1 0.21 11.8 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Stc1 PF12898.7 KIY63120.1 - 0.045 14.3 0.4 0.38 11.3 0.4 2.7 1 0 0 1 1 1 0 Stc1 domain Sec3_C_2 PF15278.6 KIY63120.1 - 0.15 12.4 2.5 0.93 9.9 0.4 3.7 2 0 0 2 2 2 0 Sec3 exocyst complex subunit AAA_16 PF13191.6 KIY63120.1 - 0.23 11.8 0.0 0.23 11.8 0.0 4.9 3 2 0 3 3 1 0 AAA ATPase domain Maelstrom PF13017.6 KIY63120.1 - 0.49 10.0 5.1 6.7 6.3 0.4 3.4 3 0 0 3 3 3 0 piRNA pathway germ-plasm component AAA_22 PF13401.6 KIY63120.1 - 1.1 9.5 0.0 1.1 9.5 0.0 4.3 4 0 0 4 4 4 0 AAA domain SNARE PF05739.19 KIY63120.1 - 1.3 9.1 5.9 5.5 7.1 1.5 3.0 2 0 0 2 2 2 0 SNARE domain adh_short PF00106.25 KIY63122.1 - 1.1e-16 60.8 0.0 1.7e-16 60.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIY63122.1 - 1.3e-10 41.2 0.0 1.8e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIY63122.1 - 5.1e-05 23.2 0.0 8.8e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.20 KIY63122.1 - 0.063 13.3 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Aa_trans PF01490.18 KIY63123.1 - 5.3e-05 22.1 14.5 0.0048 15.7 14.5 2.2 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Pox_A14 PF05767.12 KIY63123.1 - 0.065 13.4 3.5 2.1 8.5 0.2 2.8 1 1 1 2 2 2 0 Poxvirus virion envelope protein A14 DUF1198 PF06711.11 KIY63123.1 - 0.18 11.9 0.0 0.46 10.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1198) PQQ_3 PF13570.6 KIY63124.1 - 0.00068 20.0 0.2 10 6.8 0.0 3.6 3 0 0 3 3 3 2 PQQ-like domain WD40 PF00400.32 KIY63124.1 - 0.49 11.3 3.9 3.2 8.8 0.0 3.6 4 0 0 4 4 4 0 WD domain, G-beta repeat MFS_1 PF07690.16 KIY63125.1 - 3.5e-07 29.5 49.0 5.8e-06 25.5 19.1 2.8 2 1 1 3 3 3 2 Major Facilitator Superfamily YtpI PF14007.6 KIY63125.1 - 1 9.5 12.9 4.9 7.4 1.1 4.1 3 0 0 3 3 3 0 YtpI-like protein MatE PF01554.18 KIY63126.1 - 3.9e-54 182.6 30.2 8.8e-29 100.2 8.9 2.5 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 KIY63126.1 - 1.1e-06 28.7 10.3 1.1e-06 28.7 10.3 3.2 4 0 0 4 4 4 2 Polysaccharide biosynthesis C-terminal domain DUF21 PF01595.20 KIY63126.1 - 1.8 8.2 11.6 0.059 13.1 3.3 2.6 2 1 0 2 2 2 0 Cyclin M transmembrane N-terminal domain F-box-like PF12937.7 KIY63127.1 - 2.2e-08 33.8 2.2 5.3e-08 32.6 2.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY63127.1 - 0.0014 18.4 2.8 0.006 16.4 2.8 2.1 1 1 0 1 1 1 1 F-box domain F-box-like PF12937.7 KIY63128.1 - 7.3e-10 38.6 1.5 1.8e-09 37.4 0.6 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIY63128.1 - 0.0099 15.7 0.3 0.33 10.9 0.1 2.8 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KIY63129.1 - 1.7e-05 24.6 6.6 5.4e-05 23.0 6.6 1.8 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KIY63129.1 - 1.3 8.9 9.3 1 9.3 2.6 2.3 2 0 0 2 2 2 0 F-box domain Pkinase PF00069.25 KIY63131.1 - 2.9e-66 223.5 0.0 3.6e-66 223.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY63131.1 - 5.8e-29 101.1 0.0 7.8e-29 100.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY63131.1 - 0.0057 16.0 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 KIY63131.1 - 0.13 11.3 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 LigB PF02900.18 KIY63132.1 - 2.4e-36 125.2 0.0 3.2e-36 124.8 0.0 1.2 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase F-box-like PF12937.7 KIY63133.1 - 0.00048 20.0 1.4 0.0018 18.1 0.1 2.5 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 KIY63133.1 - 0.018 15.4 0.7 2.3 8.8 0.0 3.9 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) NAD_binding_4 PF07993.12 KIY63134.1 - 3.1e-50 170.7 0.0 1.1e-33 116.5 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein AMP-binding PF00501.28 KIY63134.1 - 1.2e-28 99.9 0.4 9.8e-28 96.9 0.4 2.1 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 KIY63134.1 - 2.2e-17 63.3 0.0 8e-10 38.6 0.0 2.4 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KIY63134.1 - 9.1e-07 29.1 0.0 2.1e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site KR PF08659.10 KIY63134.1 - 0.00076 19.4 0.0 0.0033 17.3 0.0 2.1 2 0 0 2 2 2 1 KR domain GDP_Man_Dehyd PF16363.5 KIY63134.1 - 0.0058 16.1 0.0 4.1 6.7 0.0 2.9 3 0 0 3 3 3 2 GDP-mannose 4,6 dehydratase GHL6 PF14871.6 KIY63134.1 - 0.027 14.6 0.0 13 5.9 0.0 2.7 2 0 0 2 2 2 0 Hypothetical glycosyl hydrolase 6 Polysacc_synt_2 PF02719.15 KIY63134.1 - 0.096 11.8 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein HNOBA PF07701.14 KIY63134.1 - 0.18 11.2 0.0 32 3.8 0.0 2.9 3 0 0 3 3 3 0 Heme NO binding associated NAD_binding_4 PF07993.12 KIY63135.1 - 1.8e-64 217.4 0.0 2.8e-64 216.7 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KIY63135.1 - 4.1e-62 210.1 0.0 6.3e-62 209.5 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 KIY63135.1 - 1.5e-12 47.7 0.0 3.9e-12 46.4 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Condensation PF00668.20 KIY63135.1 - 1.8e-10 40.1 0.0 6.9e-05 21.7 0.0 2.3 2 1 0 2 2 2 2 Condensation domain Epimerase PF01370.21 KIY63135.1 - 7.5e-07 28.9 0.0 1.5e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KIY63135.1 - 1.3e-05 24.3 0.0 2.2e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.6 KIY63135.1 - 0.00018 22.4 0.0 0.00077 20.4 0.0 2.2 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain Polysacc_synt_2 PF02719.15 KIY63135.1 - 0.027 13.6 0.1 0.32 10.1 0.0 2.3 2 1 0 2 2 2 0 Polysaccharide biosynthesis protein ABATE PF07336.11 KIY63135.1 - 0.14 12.8 2.1 6.6 7.4 0.0 3.7 3 0 0 3 3 3 0 Putative stress-induced transcription regulator F-box-like PF12937.7 KIY63136.1 - 1.6e-05 24.7 0.8 5.3e-05 23.0 0.8 2.0 1 1 0 1 1 1 1 F-box-like F-box-like PF12937.7 KIY63137.1 - 2.2e-05 24.2 0.8 0.0001 22.1 0.3 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIY63137.1 - 0.84 9.6 5.6 11 6.0 0.0 3.7 3 1 0 3 3 3 0 F-box domain Pkinase_Tyr PF07714.17 KIY63140.1 - 5e-42 144.0 0.0 6.1e-42 143.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIY63140.1 - 1.2e-35 123.2 0.0 1.5e-35 122.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Curto_V2 PF07325.11 KIY63140.1 - 0.01 15.7 0.1 0.017 15.0 0.1 1.3 1 0 0 1 1 1 0 Curtovirus V2 protein RIO1 PF01163.22 KIY63140.1 - 0.052 13.1 0.0 0.097 12.3 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 KIY63140.1 - 0.12 11.1 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Glyco_hydro_16 PF00722.21 KIY63143.1 - 1.1e-06 28.2 0.0 2.9e-06 26.9 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 PAP2 PF01569.21 KIY63145.1 - 3.4e-12 46.3 4.5 3.4e-12 46.3 4.5 1.7 1 1 1 2 2 2 1 PAP2 superfamily DUF5353 PF17304.2 KIY63145.1 - 0.095 12.5 0.6 0.2 11.4 0.6 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5353) DUF212 PF02681.14 KIY63145.1 - 0.14 12.3 0.1 0.69 10.1 0.0 2.1 2 0 0 2 2 2 0 Divergent PAP2 family CPP1-like PF11833.8 KIY63145.1 - 1.7 8.3 3.9 9.7 5.8 0.4 2.4 2 1 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like PGM_PMM_I PF02878.16 KIY63146.1 - 3e-34 117.7 0.1 4.5e-34 117.1 0.1 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 KIY63146.1 - 8.5e-26 90.4 0.0 2.3e-25 89.0 0.0 1.7 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 KIY63146.1 - 1.5e-13 51.3 0.0 4.2e-13 49.8 0.0 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 KIY63146.1 - 2.6e-05 24.3 0.0 5.9e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Zn_clus PF00172.18 KIY63147.1 - 3.2e-10 39.9 36.9 1.5e-05 25.0 11.9 2.2 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Kri1_C PF12936.7 KIY63150.1 - 3.2e-25 88.1 0.6 3.2e-25 88.1 0.6 5.9 8 0 0 8 8 8 1 KRI1-like family C-terminal Kri1 PF05178.12 KIY63150.1 - 7.7e-24 84.2 7.6 7.7e-24 84.2 7.6 6.6 5 2 2 7 7 7 1 KRI1-like family Colicin_E5 PF12106.8 KIY63150.1 - 2.3 8.6 10.0 0.34 11.2 1.0 3.2 3 0 0 3 3 3 0 Colicin E5 ribonuclease domain NACHT PF05729.12 KIY63151.1 - 3.3e-09 36.9 0.1 1.3e-07 31.7 0.0 2.8 2 1 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 KIY63151.1 - 4e-08 33.8 0.1 1.1e-06 29.1 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 KIY63151.1 - 4e-05 24.2 0.0 0.00013 22.5 0.0 1.7 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KIY63151.1 - 0.0079 16.6 0.0 0.023 15.1 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA PF00004.29 KIY63151.1 - 0.0081 16.6 1.2 0.44 11.0 0.1 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 KIY63151.1 - 0.04 13.8 0.0 0.25 11.2 0.0 2.0 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_30 PF13604.6 KIY63151.1 - 0.048 13.4 0.0 0.31 10.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KIY63151.1 - 0.064 13.5 0.0 0.2 11.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KIY63151.1 - 0.066 12.7 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_19 PF13245.6 KIY63151.1 - 0.067 13.5 0.0 0.29 11.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KIY63151.1 - 0.085 13.4 0.2 0.28 11.7 0.0 1.8 2 0 0 2 2 2 0 ABC transporter NTPase_1 PF03266.15 KIY63151.1 - 0.087 12.7 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 NTPase AAA_29 PF13555.6 KIY63151.1 - 0.094 12.5 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain zf-MYND PF01753.18 KIY63152.1 - 1.1e-06 28.6 15.2 2.9e-06 27.3 15.2 1.7 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 KIY63152.1 - 0.42 10.8 4.4 1.1 9.4 4.4 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.18 KIY63154.1 - 6.7e-08 32.5 16.4 1.7e-07 31.2 16.4 1.7 1 0 0 1 1 1 1 MYND finger G-alpha PF00503.20 KIY63155.1 - 1.5e-130 435.5 0.0 1.7e-130 435.3 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KIY63155.1 - 6.1e-10 38.8 0.1 3.8e-06 26.5 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family TniB PF05621.11 KIY63155.1 - 0.00057 19.4 0.0 0.001 18.5 0.0 1.4 1 0 0 1 1 1 1 Bacterial TniB protein Roc PF08477.13 KIY63155.1 - 0.019 15.2 0.0 5.5 7.2 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DAP3 PF10236.9 KIY63155.1 - 0.03 13.5 0.0 0.059 12.5 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_29 PF13555.6 KIY63155.1 - 0.032 14.0 0.0 0.068 12.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.27 KIY63155.1 - 0.11 12.0 0.0 1.4 8.4 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Ras PF00071.22 KIY63155.1 - 0.12 11.9 0.0 11 5.6 0.0 2.5 2 1 0 2 2 2 0 Ras family ABC_tran PF00005.27 KIY63155.1 - 0.14 12.6 0.0 0.32 11.5 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Alpha-amylase PF00128.24 KIY63156.1 - 1.5e-26 93.7 0.2 3.8e-26 92.5 0.2 1.6 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.16 KIY63156.1 - 9.4e-09 34.0 0.6 0.007 14.6 0.0 3.1 3 0 0 3 3 3 3 Glycosyl hydrolase family 70 DUF1939 PF09154.10 KIY63156.1 - 0.00019 21.5 0.3 0.00066 19.8 0.3 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1939) Apo-CIII PF05778.12 KIY63156.1 - 0.15 11.7 2.9 51 3.6 0.0 4.0 4 0 0 4 4 4 0 Apolipoprotein CIII (Apo-CIII) SprA-related PF12118.8 KIY63158.1 - 0.47 9.6 14.2 0.71 8.9 14.2 1.2 1 0 0 1 1 1 0 SprA-related family Merozoite_SPAM PF07133.11 KIY63158.1 - 0.79 9.7 18.9 1.1 9.2 18.9 1.1 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) XRCC4 PF06632.12 KIY63158.1 - 1.1 8.1 13.7 1.6 7.5 13.7 1.2 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Presenilin PF01080.17 KIY63158.1 - 2.2 7.0 12.7 3.1 6.4 12.7 1.2 1 0 0 1 1 1 0 Presenilin PAT1 PF09770.9 KIY63158.1 - 4.5 5.4 12.3 5.9 5.0 12.3 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Plasmodium_Vir PF05795.11 KIY63158.1 - 5.4 6.3 6.7 8.3 5.7 6.7 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF2151 PF10221.9 KIY63158.1 - 6.9 5.1 9.4 9.3 4.7 9.4 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator TERB2 PF15101.6 KIY63158.1 - 7.2 6.6 9.5 11 6.0 9.5 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 SLC12 PF03522.15 KIY63158.1 - 7.3 5.5 7.7 9.8 5.1 7.7 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Hid1 PF12722.7 KIY63158.1 - 7.5 4.6 12.6 10 4.1 12.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4407 PF14362.6 KIY63158.1 - 9.3 5.5 9.9 13 5.0 9.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) UNC-50 PF05216.13 KIY63159.1 - 4.6e-86 287.9 14.6 5.2e-86 287.8 14.6 1.0 1 0 0 1 1 1 1 UNC-50 family DUF5345 PF17280.2 KIY63159.1 - 0.071 13.1 0.5 0.16 12.0 0.5 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5345) Ig_J_chain PF15097.6 KIY63160.1 - 0.24 11.3 0.0 0.55 10.1 0.0 1.5 1 0 0 1 1 1 0 Immunoglobulin J chain F-box-like PF12937.7 KIY63162.1 - 2e-07 30.8 0.6 6.6e-07 29.1 0.6 2.0 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KIY63162.1 - 0.29 11.6 3.6 56 4.4 0.0 4.2 1 1 2 3 3 3 0 Leucine Rich repeats (2 copies) DEAD PF00270.29 KIY63164.1 - 2.1e-20 73.2 0.0 4e-20 72.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIY63164.1 - 1.1e-13 51.5 0.0 7.2e-13 48.9 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF1998 PF09369.10 KIY63164.1 - 4.5e-12 46.6 3.4 6.7e-12 46.0 1.6 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1998) ResIII PF04851.15 KIY63164.1 - 6.8e-09 36.0 0.0 1.5e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CDT1 PF08839.11 KIY63164.1 - 0.046 14.0 0.0 0.087 13.1 0.0 1.4 1 0 0 1 1 1 0 DNA replication factor CDT1 like DUF4145 PF13643.6 KIY63164.1 - 0.08 13.1 0.1 1.6 8.9 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4145) stn_TNFRSF12A PF12191.8 KIY63165.1 - 0.0059 16.8 0.0 0.012 15.8 0.0 1.7 1 0 0 1 1 1 1 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Herpes_gE PF02480.16 KIY63165.1 - 0.02 13.7 0.1 0.035 12.9 0.0 1.4 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E Phage_HK97_TLTM PF06120.11 KIY63165.1 - 0.063 12.5 0.3 0.085 12.0 0.3 1.1 1 0 0 1 1 1 0 Tail length tape measure protein SKG6 PF08693.10 KIY63165.1 - 0.093 12.2 3.5 0.45 10.0 2.3 2.2 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Mlh1_C PF16413.5 KIY63167.1 - 1.7e-91 306.4 0.1 3.1e-91 305.5 0.1 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 KIY63167.1 - 4.5e-29 100.5 0.0 7.3e-29 99.9 0.0 1.3 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 KIY63167.1 - 3.7e-12 46.3 0.0 8.3e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KIY63167.1 - 7e-07 29.7 0.0 1.6e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MOR2-PAG1_N PF14222.6 KIY63168.1 - 4.4e-157 524.4 0.1 6.4e-157 523.8 0.1 1.3 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 KIY63168.1 - 4e-80 269.3 0.8 9.3e-80 268.1 0.8 1.7 1 0 0 1 1 1 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.6 KIY63168.1 - 4.5e-15 54.4 0.0 6.4e-13 47.3 0.0 2.2 2 0 0 2 2 2 2 Cell morphogenesis central region DUF5629 PF18629.1 KIY63168.1 - 0.15 12.6 0.2 0.5 11.0 0.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5629) mRNA_decap_C PF16741.5 KIY63171.1 - 0.049 12.9 0.0 0.091 12.1 0.0 1.4 1 0 0 1 1 1 0 mRNA-decapping enzyme C-terminus Peptidase_M28 PF04389.17 KIY63172.1 - 2e-25 89.6 0.0 3.6e-25 88.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KIY63172.1 - 1.8e-06 27.8 0.2 1.3e-05 25.0 0.2 2.2 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 DnaG_DnaB_bind PF08278.11 KIY63172.1 - 0.14 12.8 0.3 3 8.5 0.1 2.4 2 0 0 2 2 2 0 DNA primase DnaG DnaB-binding GPI-anchored PF10342.9 KIY63173.1 - 0.00013 22.6 0.0 0.00021 22.0 0.0 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4514 PF14986.6 KIY63174.1 - 0.086 12.8 0.1 0.13 12.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4514) BTG PF07742.12 KIY63176.1 - 0.16 11.8 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 BTG family DUF5127 PF17168.4 KIY63177.1 - 7.1e-55 186.2 1.8 1e-54 185.7 1.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF1793 PF08760.11 KIY63177.1 - 2.8e-35 122.2 0.9 2.8e-35 122.2 0.9 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF1793) DUF4965 PF16335.5 KIY63177.1 - 1.6e-33 115.8 0.2 2.8e-33 115.0 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) Bac_rhamnosid6H PF17389.2 KIY63177.1 - 0.0093 15.3 0.4 0.14 11.3 0.4 2.4 1 1 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain DUF3847 PF12958.7 KIY63179.1 - 0.048 13.8 1.2 0.13 12.4 1.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3847) ASTN_2_hairpin PF18577.1 KIY63179.1 - 0.43 10.7 0.2 0.43 10.7 0.2 2.4 2 0 0 2 2 2 0 Astrotactin-2 C-terminal beta-hairpin domain Thioredoxin_4 PF13462.6 KIY63180.1 - 0.027 14.6 0.5 3.8 7.7 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin RhoGEF PF00621.20 KIY63183.1 - 5.7e-35 121.2 0.0 8.5e-35 120.6 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain FYVE PF01363.21 KIY63183.1 - 1.1e-17 64.0 11.9 1.9e-17 63.2 11.9 1.4 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.29 KIY63183.1 - 0.0015 19.0 0.0 0.0089 16.5 0.0 2.3 2 0 0 2 2 2 1 PH domain FYVE_2 PF02318.16 KIY63183.1 - 6.8 6.9 9.5 14 5.9 9.5 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger AAA_12 PF13087.6 KIY63188.1 - 4.6e-53 179.8 0.0 6.9e-53 179.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KIY63188.1 - 4.3e-48 164.4 0.0 6.1e-48 163.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KIY63188.1 - 3.9e-14 53.2 0.0 1.4e-13 51.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KIY63188.1 - 1.5e-13 50.9 0.0 2.2e-07 30.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain UvrD-helicase PF00580.21 KIY63188.1 - 4.3e-06 26.5 0.0 1.2e-05 25.1 0.0 1.8 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.18 KIY63188.1 - 7.7e-05 22.5 0.0 2.3 7.9 0.0 3.2 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase PhoH PF02562.16 KIY63188.1 - 0.048 13.1 0.0 0.086 12.3 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein DUF2075 PF09848.9 KIY63188.1 - 0.14 11.3 0.1 3.9 6.6 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 KIY63188.1 - 0.15 12.3 0.0 0.36 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KIY63188.1 - 0.19 12.2 0.1 0.74 10.2 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) OTT_1508_deam PF14441.6 KIY63189.1 - 1.7e-07 31.1 0.1 3.4e-07 30.2 0.1 1.5 1 0 0 1 1 1 1 OTT_1508-like deaminase RRM_1 PF00076.22 KIY63190.1 - 1.4e-55 185.0 0.0 8.2e-16 57.6 0.0 5.7 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KIY63190.1 - 2.8e-05 24.2 0.0 1.3 9.1 0.0 4.3 4 0 0 4 4 4 1 RNA recognition motif RRM_Rrp7 PF17799.1 KIY63190.1 - 0.004 17.0 0.3 16 5.2 0.0 4.0 3 1 1 4 4 4 1 Rrp7 RRM-like N-terminal domain RRM_3 PF08777.11 KIY63190.1 - 0.0052 16.8 8.1 0.97 9.5 0.0 5.0 5 1 0 5 5 5 2 RNA binding motif Limkain-b1 PF11608.8 KIY63190.1 - 0.019 15.1 0.0 0.67 10.1 0.0 3.3 3 1 0 3 3 3 0 Limkain b1 RNA_bind PF08675.11 KIY63190.1 - 0.09 12.8 0.1 1.8 8.7 0.0 2.9 3 0 0 3 3 3 0 RNA binding domain RRM_8 PF11835.8 KIY63190.1 - 0.11 12.7 0.0 2.1 8.6 0.0 2.9 3 0 0 3 3 3 0 RRM-like domain KOW PF00467.29 KIY63191.1 - 3e-24 84.1 16.3 9.5e-07 28.6 0.3 7.3 7 0 0 7 7 7 5 KOW motif Spt5-NGN PF03439.13 KIY63191.1 - 1e-19 70.2 0.0 1.9e-19 69.3 0.0 1.5 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.8 KIY63191.1 - 3e-16 60.2 6.6 3e-16 60.2 6.6 2.8 2 1 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal CTD PF12815.7 KIY63191.1 - 8e-10 39.1 66.2 1.1e-09 38.7 14.8 3.7 1 1 1 2 2 2 1 Spt5 C-terminal nonapeptide repeat binding Spt4 PPV_E1_N PF00524.18 KIY63191.1 - 0.016 15.7 0.6 0.016 15.7 0.6 2.3 1 1 1 2 2 2 0 E1 Protein, N terminal domain Pkinase_Tyr PF07714.17 KIY63192.1 - 9.8e-46 156.1 0.0 1.7e-45 155.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIY63192.1 - 4.3e-37 127.9 0.0 1.1e-36 126.6 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain RasGEF PF00617.19 KIY63192.1 - 3.5e-22 79.5 0.0 8.4e-22 78.2 0.0 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KIY63192.1 - 8.2e-07 29.2 0.0 1.9e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif pXO2-72 PF17443.2 KIY63192.1 - 2.2 8.6 4.6 7.9 6.8 0.5 2.6 2 0 0 2 2 2 0 Uncharacterized protein pXO2-72 RasGEF PF00617.19 KIY63194.1 - 2e-17 64.0 0.0 3.4e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KIY63194.1 - 3.3e-07 30.5 0.0 7.6e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif F-box-like PF12937.7 KIY63195.1 - 1.1e-06 28.4 1.7 3.4e-06 26.9 1.7 1.9 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KIY63195.1 - 0.42 10.6 1.5 28 4.7 0.2 2.6 2 0 0 2 2 2 0 F-box domain COQ7 PF03232.13 KIY63197.1 - 6.3e-67 224.6 0.5 7.3e-67 224.4 0.5 1.0 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.17 KIY63197.1 - 0.0022 18.4 0.1 0.058 13.8 0.0 2.1 1 1 1 2 2 2 1 Rubrerythrin DUF4279 PF14106.6 KIY63197.1 - 0.096 12.9 0.1 0.33 11.2 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4279) SecA_SW PF07516.13 KIY63197.1 - 0.11 12.5 0.1 0.15 12.1 0.1 1.1 1 0 0 1 1 1 0 SecA Wing and Scaffold domain zf-RING_UBOX PF13445.6 KIY63199.1 - 5.8e-10 39.0 7.8 5.8e-10 39.0 7.8 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KIY63199.1 - 3.1e-08 33.3 9.8 4.8e-08 32.7 9.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIY63199.1 - 1.8e-07 30.9 13.4 2.8e-07 30.3 13.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIY63199.1 - 1.7e-06 28.2 13.3 2.9e-06 27.5 13.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 KIY63199.1 - 4.8e-06 26.6 15.8 8.2e-06 25.9 15.8 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 KIY63199.1 - 5e-06 26.2 12.5 1.2e-05 25.0 12.5 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIY63199.1 - 2.6e-05 24.1 12.1 4.3e-05 23.4 12.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KIY63199.1 - 0.00054 19.8 11.7 0.0011 18.7 11.7 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 KIY63199.1 - 0.00066 19.5 9.7 0.0015 18.3 9.7 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein ZapB PF06005.12 KIY63199.1 - 0.0011 19.4 10.8 0.0037 17.7 3.8 2.3 2 0 0 2 2 2 1 Cell division protein ZapB bZIP_1 PF00170.21 KIY63199.1 - 0.0039 17.3 4.0 0.53 10.4 0.3 2.4 2 0 0 2 2 2 2 bZIP transcription factor zf-RING_11 PF17123.5 KIY63199.1 - 0.0097 15.6 8.7 0.025 14.3 8.7 1.8 1 0 0 1 1 1 1 RING-like zinc finger TSC22 PF01166.18 KIY63199.1 - 0.014 15.7 4.2 0.061 13.6 0.7 2.3 2 0 0 2 2 2 0 TSC-22/dip/bun family MAD PF05557.13 KIY63199.1 - 0.028 12.8 10.8 0.04 12.3 10.8 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein HALZ PF02183.18 KIY63199.1 - 0.028 14.7 4.6 0.29 11.4 0.3 2.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper DASH_Spc19 PF08287.11 KIY63199.1 - 0.058 13.3 8.6 0.13 12.1 7.4 2.0 1 1 1 2 2 2 0 Spc19 bZIP_2 PF07716.15 KIY63199.1 - 0.14 12.2 7.9 1.1 9.4 1.1 2.5 2 0 0 2 2 2 0 Basic region leucine zipper V_ATPase_I PF01496.19 KIY63199.1 - 0.17 9.8 1.3 0.22 9.4 1.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family YabA PF06156.13 KIY63199.1 - 0.27 11.9 7.4 0.44 11.2 2.4 2.3 1 1 1 2 2 2 0 Initiation control protein YabA zf-Nse PF11789.8 KIY63199.1 - 0.58 10.0 5.6 1 9.3 5.6 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FYVE PF01363.21 KIY63199.1 - 0.77 9.9 10.7 11 6.2 11.5 2.2 1 1 1 2 2 2 0 FYVE zinc finger NRBF2 PF08961.10 KIY63199.1 - 1.9 8.1 9.1 0.22 11.1 2.5 2.2 1 1 1 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator MCC-bdg_PDZ PF10506.9 KIY63199.1 - 2.2 8.4 8.5 1.4 9.0 0.6 2.5 2 1 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome IMUP PF15761.5 KIY63199.1 - 2.7 8.7 5.9 2 9.1 1.3 2.5 2 0 0 2 2 2 0 Immortalisation up-regulated protein zf-RING_4 PF14570.6 KIY63199.1 - 6.5 6.6 11.9 13 5.7 11.9 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain SHE3 PF17078.5 KIY63199.1 - 7.1 6.3 10.6 1.1 8.9 6.7 1.6 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 Amidase PF01425.21 KIY63200.1 - 2e-121 406.1 1.0 2.4e-121 405.9 1.0 1.0 1 0 0 1 1 1 1 Amidase AA_permease PF00324.21 KIY63201.1 - 7.8e-131 437.0 37.3 9.5e-131 436.7 37.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KIY63201.1 - 1.6e-34 119.5 40.5 2.2e-34 119.0 40.4 1.2 1 1 0 1 1 1 1 Amino acid permease DUF924 PF06041.11 KIY63203.1 - 6.7e-22 78.5 0.0 1.5e-21 77.4 0.0 1.4 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF924) Fez1 PF06818.15 KIY63205.1 - 0.0026 18.2 29.1 0.46 10.9 16.9 3.0 2 1 1 3 3 3 2 Fez1 DUF4047 PF13256.6 KIY63205.1 - 0.023 14.9 6.9 0.46 10.7 1.7 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4047) TACC_C PF05010.14 KIY63205.1 - 0.025 14.4 23.6 0.011 15.5 21.2 1.6 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF5082 PF16888.5 KIY63205.1 - 0.078 13.3 19.9 0.14 12.4 3.7 4.3 2 1 2 4 4 4 0 Domain of unknown function (DUF5082) ERM PF00769.19 KIY63205.1 - 0.1 12.4 26.0 0.18 11.6 26.0 1.5 1 0 0 1 1 1 0 Ezrin/radixin/moesin family TSC22 PF01166.18 KIY63205.1 - 0.19 12.1 14.8 10 6.5 0.0 5.8 5 1 1 6 6 6 0 TSC-22/dip/bun family Prominin PF05478.11 KIY63205.1 - 0.78 7.6 13.7 0.5 8.3 4.3 2.1 1 1 1 2 2 2 0 Prominin DUF1515 PF07439.11 KIY63205.1 - 0.79 9.8 16.6 0.19 11.8 1.5 3.8 2 2 1 3 3 3 0 Protein of unknown function (DUF1515) ATG16 PF08614.11 KIY63205.1 - 1.3 9.2 38.1 0.71 10.1 6.5 3.7 2 1 2 4 4 4 0 Autophagy protein 16 (ATG16) Jnk-SapK_ap_N PF09744.9 KIY63205.1 - 2.2 8.5 28.1 1.8 8.8 3.3 2.9 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 CENP-F_leu_zip PF10473.9 KIY63205.1 - 2.7 8.0 33.6 9.3 6.3 5.6 3.2 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 KIY63205.1 - 3.3 6.5 35.3 0.5 9.2 6.9 2.7 2 1 1 3 3 3 0 Spc7 kinetochore protein APG17 PF04108.12 KIY63205.1 - 3.7 6.5 20.8 9.2 5.3 20.1 2.0 2 1 0 2 2 2 0 Autophagy protein Apg17 DUF3584 PF12128.8 KIY63205.1 - 4 4.8 24.2 8.8 3.7 24.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) YabA PF06156.13 KIY63205.1 - 8.8 7.0 21.2 72 4.1 11.5 4.2 2 1 2 4 4 4 0 Initiation control protein YabA Golgin_A5 PF09787.9 KIY63205.1 - 9.3 5.6 28.6 3 7.2 0.3 3.2 2 1 3 5 5 5 0 Golgin subfamily A member 5 Baculo_PEP_C PF04513.12 KIY63205.1 - 9.9 6.2 14.1 15 5.6 0.0 3.5 2 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus RCDG1 PF15725.5 KIY63206.1 - 0.12 12.8 4.7 0.34 11.4 4.7 1.8 1 0 0 1 1 1 0 Renal cancer differentiation gene 1 protein Glyco_hydro_61 PF03443.14 KIY63207.1 - 6.2e-62 209.2 0.0 7.4e-62 208.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 TPR_2 PF07719.17 KIY63208.1 - 1.1e-16 59.5 0.4 4.7e-05 23.2 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 KIY63208.1 - 3.7e-16 58.2 0.3 6.1e-05 22.7 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 KIY63208.1 - 2.1e-10 40.1 0.6 8.8e-09 34.9 1.2 2.3 2 0 0 2 2 2 1 TPR repeat TPR_12 PF13424.6 KIY63208.1 - 6.4e-09 36.0 4.0 6.8e-05 23.1 0.3 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KIY63208.1 - 3.2e-08 34.1 0.9 3.3e-05 24.4 0.1 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 KIY63208.1 - 7.1e-08 32.7 1.8 0.006 17.3 0.0 3.5 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KIY63208.1 - 1.7e-07 31.6 1.1 1.2e-05 25.8 0.3 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KIY63208.1 - 7.3e-07 28.9 0.2 1.2 9.5 0.3 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 KIY63208.1 - 7.6e-07 29.4 1.4 0.058 14.1 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KIY63208.1 - 2.5e-06 27.1 1.2 0.083 13.0 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KIY63208.1 - 0.00015 21.9 0.9 0.00054 20.1 0.7 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 KIY63208.1 - 0.00081 19.5 3.2 0.26 11.5 0.1 2.8 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 KIY63208.1 - 0.0015 18.4 7.2 0.11 12.4 0.1 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_15 PF13429.6 KIY63208.1 - 0.0061 15.8 0.5 0.012 14.8 0.5 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat BTAD PF03704.17 KIY63208.1 - 0.053 14.0 1.5 0.16 12.4 1.5 1.8 1 1 0 1 1 1 0 Bacterial transcriptional activator domain F-box-like PF12937.7 KIY63209.1 - 0.00022 21.0 1.2 0.0011 18.9 0.0 2.5 2 1 0 2 2 2 1 F-box-like F-box PF00646.33 KIY63209.1 - 0.062 13.2 1.5 3.7 7.5 0.1 2.7 2 0 0 2 2 2 0 F-box domain BNR_2 PF13088.6 KIY63212.1 - 1.3e-11 44.3 0.3 7.6e-06 25.4 0.1 2.9 1 1 2 3 3 3 3 BNR repeat-like domain BNR PF02012.20 KIY63212.1 - 5e-05 22.7 13.4 1.1 9.5 0.7 4.8 4 0 0 4 4 4 4 BNR/Asp-box repeat AMP-binding PF00501.28 KIY63213.1 - 1.2e-85 287.6 0.0 1.7e-85 287.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KIY63213.1 - 4.6e-11 43.5 0.5 2.8e-10 41.0 0.3 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DUF1069 PF06370.11 KIY63213.1 - 0.048 13.2 0.1 0.088 12.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1069) AMP-binding PF00501.28 KIY63214.1 - 2.6e-90 303.0 0.3 3.2e-90 302.7 0.3 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KIY63214.1 - 8.8e-13 49.0 0.4 2.3e-12 47.7 0.4 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain BUD22 PF09073.10 KIY63215.1 - 0.0021 17.5 27.7 0.0025 17.2 27.7 1.3 1 0 0 1 1 1 1 BUD22 U3_snoRNA_assoc PF08297.11 KIY63215.1 - 0.0022 18.6 1.1 0.0022 18.6 1.1 3.4 2 1 1 3 3 3 1 U3 snoRNA associated Plasmodium_Vir PF05795.11 KIY63215.1 - 0.023 14.1 9.2 0.028 13.8 9.2 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF572 PF04502.13 KIY63215.1 - 0.68 9.5 22.9 0.98 9.0 22.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) GREB1 PF15782.5 KIY63215.1 - 0.74 6.9 17.8 0.92 6.5 17.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Nop14 PF04147.12 KIY63215.1 - 4.5 5.4 29.7 5.5 5.1 29.7 1.1 1 0 0 1 1 1 0 Nop14-like family GST_N PF02798.20 KIY63216.1 - 4.2e-17 62.3 0.0 7e-17 61.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KIY63216.1 - 1.5e-14 54.2 0.0 2.6e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KIY63216.1 - 1.5e-14 54.0 0.1 2.5e-14 53.3 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KIY63216.1 - 1.7e-09 37.8 0.0 3.1e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KIY63216.1 - 3.2e-08 33.7 0.0 5.9e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KIY63216.1 - 3.9e-06 26.8 0.0 7.2e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KIY63216.1 - 0.14 12.9 0.0 0.24 12.2 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain LCAT PF02450.15 KIY63217.1 - 1.1e-79 268.5 0.0 1.8e-78 264.4 0.0 2.0 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase Lipase_2 PF01674.18 KIY63217.1 - 0.064 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 2) Trp_halogenase PF04820.14 KIY63219.1 - 2.1e-30 106.0 1.7 1.6e-15 56.9 0.1 3.0 2 1 1 3 3 3 3 Tryptophan halogenase FAD_binding_3 PF01494.19 KIY63219.1 - 7.1e-14 51.8 0.0 7.4e-07 28.7 0.0 2.4 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KIY63219.1 - 1.1e-05 25.5 0.1 3.5e-05 23.9 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KIY63219.1 - 7.2e-05 22.3 0.1 0.00014 21.3 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KIY63219.1 - 7.9e-05 21.5 0.2 0.00016 20.5 0.2 1.5 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 KIY63219.1 - 0.00036 19.8 0.1 0.00058 19.1 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KIY63219.1 - 0.0013 18.4 0.6 0.031 13.9 0.1 2.8 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIY63219.1 - 0.0017 17.6 0.0 0.0028 16.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KIY63219.1 - 0.0041 16.3 0.0 0.0058 15.8 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KIY63219.1 - 0.0049 16.2 0.0 0.013 14.8 0.2 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KIY63219.1 - 0.0094 15.3 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 KIY63219.1 - 0.064 12.5 0.1 0.11 11.8 0.1 1.2 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 KIY63219.1 - 0.094 11.7 0.1 0.19 10.7 0.1 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein PTCB-BRCT PF12738.7 KIY63220.1 - 0.00033 20.6 0.0 0.00048 20.0 0.0 1.4 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 KIY63220.1 - 0.0004 20.7 0.0 0.00056 20.2 0.0 1.3 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KIY63220.1 - 0.0035 17.7 0.0 0.0055 17.1 0.0 1.3 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 KIY63220.1 - 0.083 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain NAD_kinase PF01513.21 KIY63222.1 - 6.2e-65 219.3 0.0 8.2e-65 218.9 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 KIY63222.1 - 0.075 12.6 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Bac_rhamnosid_N PF08531.10 KIY63225.1 - 0.083 12.7 0.0 0.096 12.5 0.0 1.1 1 0 0 1 1 1 0 Alpha-L-rhamnosidase N-terminal domain XPG_I_2 PF12813.7 KIY63226.1 - 1.6e-05 24.5 0.0 0.0067 15.9 0.0 2.9 2 1 0 2 2 2 2 XPG domain containing XPG_N PF00752.17 KIY63226.1 - 0.085 13.3 0.0 0.63 10.5 0.0 2.4 3 0 0 3 3 3 0 XPG N-terminal domain Plavaka PF18759.1 KIY63227.1 - 3.5e-13 49.5 0.0 5e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 Plavaka transposase DUF4754 PF15946.5 KIY63228.1 - 0.021 15.1 0.6 11 6.3 0.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4754) Ribosomal_L27e PF01777.18 KIY63228.1 - 0.08 13.3 0.6 4.6 7.7 0.1 2.4 2 0 0 2 2 2 0 Ribosomal L27e protein family Malate_DH PF12434.8 KIY63228.1 - 1.7 8.8 6.1 15 5.7 0.6 2.5 2 0 0 2 2 2 0 Malate dehydrogenase enzyme AflR PF08493.10 KIY63229.1 - 0.023 14.2 0.1 0.041 13.4 0.1 1.4 1 0 0 1 1 1 0 Aflatoxin regulatory protein Lipase_GDSL_2 PF13472.6 KIY63230.1 - 1.6e-20 74.3 1.2 2.5e-20 73.6 1.2 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KIY63230.1 - 2e-07 31.2 0.0 2.8e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Amidohydro_3 PF07969.11 KIY63231.1 - 0.002 17.7 2.7 0.027 14.0 0.1 3.4 4 0 0 4 4 4 1 Amidohydrolase family Amidohydro_1 PF01979.20 KIY63231.1 - 0.18 11.1 0.9 2 7.7 0.4 2.9 2 1 0 2 2 2 0 Amidohydrolase family Abhydrolase_1 PF00561.20 KIY63233.1 - 1.5e-19 70.7 0.2 1.7e-15 57.4 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIY63233.1 - 7e-16 58.2 0.0 2.3e-15 56.5 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KIY63233.1 - 1.2e-15 58.7 2.3 1.7e-15 58.2 2.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 KIY63233.1 - 0.00034 20.4 0.0 0.71 9.6 0.0 2.7 3 0 0 3 3 3 2 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 KIY63233.1 - 0.0019 18.3 0.0 0.0029 17.7 0.0 1.2 1 0 0 1 1 1 1 TAP-like protein DLH PF01738.18 KIY63233.1 - 0.0023 17.5 0.0 0.21 11.1 0.0 2.3 2 0 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 KIY63233.1 - 0.015 14.8 0.0 0.79 9.2 0.0 2.5 2 1 0 2 2 2 0 Prolyl oligopeptidase family Shugoshin_N PF07558.11 KIY63234.1 - 3.7e-06 26.7 2.5 6.1e-06 26.0 2.5 1.3 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region CCDC144C PF14915.6 KIY63234.1 - 0.083 12.0 0.3 0.12 11.4 0.3 1.1 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region RIO1 PF01163.22 KIY63235.1 - 2.7e-05 23.9 0.0 3.6e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KIY63235.1 - 0.0074 16.2 0.1 0.047 13.6 0.1 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 KIY63235.1 - 0.062 12.7 0.0 0.097 12.0 0.0 1.3 1 1 0 1 1 1 0 Protein kinase domain WaaY PF06176.11 KIY63235.1 - 0.14 11.8 0.0 0.17 11.5 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Stealth_CR3 PF17102.5 KIY63236.1 - 0.049 13.5 1.0 0.13 12.2 1.0 1.8 1 0 0 1 1 1 0 Stealth protein CR3, conserved region 3 Nfu_N PF08712.11 KIY63238.1 - 5e-30 103.4 0.0 1.6e-29 101.8 0.0 1.9 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 KIY63238.1 - 7.7e-28 96.5 0.1 1.3e-27 95.7 0.1 1.4 1 0 0 1 1 1 1 NifU-like domain YojJ PF10372.9 KIY63238.1 - 0.024 14.7 0.2 0.069 13.3 0.3 1.7 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus UQ_con PF00179.26 KIY63239.1 - 5e-29 100.7 0.0 6e-29 100.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 KIY63239.1 - 0.068 13.0 0.0 0.085 12.7 0.0 1.2 1 0 0 1 1 1 0 UEV domain UFC1 PF08694.11 KIY63239.1 - 0.15 11.7 0.0 0.25 11.0 0.0 1.4 1 1 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 SAP30_Sin3_bdg PF13867.6 KIY63240.1 - 0.12 12.7 0.1 3.6 8.0 0.0 2.4 2 0 0 2 2 2 0 Sin3 binding region of histone deacetylase complex subunit SAP30 Chorismate_synt PF01264.21 KIY63243.1 - 5.8e-139 462.3 0.0 6.7e-139 462.2 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase UPF0052 PF01933.18 KIY63245.1 - 9.8e-47 159.6 0.0 1.3e-46 159.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 ABC_tran PF00005.27 KIY63247.1 - 2.1e-47 161.1 0.0 2.1e-22 80.1 0.0 3.2 3 0 0 3 3 3 2 ABC transporter ABC_tran_Xtn PF12848.7 KIY63247.1 - 1.2e-21 76.5 2.5 1.2e-21 76.5 2.5 2.8 2 1 1 3 3 1 1 ABC transporter AAA_21 PF13304.6 KIY63247.1 - 2.4e-16 60.4 13.5 0.00057 19.8 0.3 4.7 3 2 2 5 5 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KIY63247.1 - 3.4e-11 43.0 1.0 0.00024 20.6 0.0 4.2 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KIY63247.1 - 1.1e-07 31.5 0.4 0.0071 16.1 0.2 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KIY63247.1 - 1.1e-07 31.9 0.0 0.0089 16.1 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 KIY63247.1 - 7.1e-07 29.8 2.7 0.043 14.2 0.1 3.4 3 0 0 3 3 3 2 AAA ATPase domain RsgA_GTPase PF03193.16 KIY63247.1 - 4.3e-06 26.7 1.2 0.065 13.1 0.0 2.6 2 1 0 2 2 2 2 RsgA GTPase AAA_18 PF13238.6 KIY63247.1 - 7e-06 26.6 0.5 0.22 12.1 0.0 4.0 4 0 0 4 4 4 2 AAA domain NACHT PF05729.12 KIY63247.1 - 9.6e-06 25.6 0.3 0.15 11.9 0.0 3.0 3 0 0 3 3 3 2 NACHT domain AAA_28 PF13521.6 KIY63247.1 - 2.2e-05 24.8 0.0 0.33 11.2 0.0 2.9 2 0 0 2 2 2 2 AAA domain MeaB PF03308.16 KIY63247.1 - 3.8e-05 22.8 0.2 0.078 11.9 0.1 2.6 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 KIY63247.1 - 5.5e-05 23.5 2.0 0.61 10.4 0.0 3.7 3 2 0 3 3 3 2 AAA domain AAA_33 PF13671.6 KIY63247.1 - 0.00029 21.0 0.2 0.31 11.2 0.0 3.1 3 0 0 3 3 2 1 AAA domain AAA_15 PF13175.6 KIY63247.1 - 0.00037 20.3 4.5 0.18 11.5 0.3 3.4 3 0 0 3 3 3 2 AAA ATPase domain AAA_24 PF13479.6 KIY63247.1 - 0.0017 18.1 0.0 1.8 8.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 KIY63247.1 - 0.0022 18.6 19.5 0.27 11.7 0.0 4.7 5 0 0 5 5 5 2 AAA domain Dynamin_N PF00350.23 KIY63247.1 - 0.0028 17.7 1.2 0.11 12.6 0.0 3.0 3 1 0 3 3 2 1 Dynamin family RNA_helicase PF00910.22 KIY63247.1 - 0.0042 17.5 0.0 2.7 8.4 0.0 2.6 2 0 0 2 2 2 1 RNA helicase NB-ARC PF00931.22 KIY63247.1 - 0.0059 15.8 0.0 2.8 7.1 0.0 2.7 2 0 0 2 2 2 1 NB-ARC domain AAA PF00004.29 KIY63247.1 - 0.008 16.6 0.0 4.7 7.6 0.0 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 KIY63247.1 - 0.0087 16.0 0.1 3.1 7.7 0.1 2.5 2 0 0 2 2 2 1 NTPase SbcCD_C PF13558.6 KIY63247.1 - 0.0092 16.2 0.3 1.3 9.3 0.2 3.9 3 2 0 3 3 3 1 Putative exonuclease SbcCD, C subunit DUF87 PF01935.17 KIY63247.1 - 0.01 15.9 10.8 0.015 15.4 0.1 3.7 3 1 1 4 4 4 0 Helicase HerA, central domain Roc PF08477.13 KIY63247.1 - 0.012 15.9 0.1 5.9 7.1 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_14 PF13173.6 KIY63247.1 - 0.013 15.5 0.0 5.9 6.9 0.0 3.2 3 0 0 3 3 2 0 AAA domain AAA_7 PF12775.7 KIY63247.1 - 0.015 14.8 0.1 4.5 6.8 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region ATPase_2 PF01637.18 KIY63247.1 - 0.016 15.1 0.2 3.5 7.5 0.0 2.8 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea FtsK_SpoIIIE PF01580.18 KIY63247.1 - 0.02 14.3 0.2 0.35 10.2 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family cobW PF02492.19 KIY63247.1 - 0.028 14.0 0.1 8.9 5.9 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.6 KIY63247.1 - 0.048 13.2 0.5 11 5.6 0.0 3.5 3 1 0 3 3 3 0 AAA domain AAA_30 PF13604.6 KIY63247.1 - 0.054 13.2 4.5 1.7 8.4 0.1 3.2 3 1 0 3 3 2 0 AAA domain AAA_5 PF07728.14 KIY63247.1 - 0.055 13.5 0.2 15 5.5 0.0 3.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) PduV-EutP PF10662.9 KIY63247.1 - 0.077 12.7 0.0 2.3 7.9 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATP-synt_ab PF00006.25 KIY63247.1 - 0.079 12.6 0.0 0.52 9.9 0.0 2.1 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Ploopntkinase3 PF18751.1 KIY63247.1 - 0.1 12.5 0.0 4.1 7.3 0.0 2.7 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 Viral_helicase1 PF01443.18 KIY63247.1 - 0.16 11.7 0.0 6.4 6.4 0.1 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase FeoB_N PF02421.18 KIY63247.1 - 0.17 11.4 0.0 2.7 7.5 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B TPR_1 PF00515.28 KIY63249.1 - 3.7e-51 169.0 20.0 2.5e-07 30.2 0.0 10.9 11 1 0 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.17 KIY63249.1 - 5.4e-48 157.3 15.7 0.0001 22.2 0.0 10.5 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_8 PF13181.6 KIY63249.1 - 6.9e-37 122.6 6.8 0.00046 20.2 1.6 10.8 10 1 0 10 10 10 9 Tetratricopeptide repeat TPR_14 PF13428.6 KIY63249.1 - 7.2e-26 88.7 6.1 0.0071 17.1 0.0 9.5 3 3 7 10 10 10 6 Tetratricopeptide repeat TPR_16 PF13432.6 KIY63249.1 - 4.8e-25 87.9 9.8 5.2e-07 30.2 0.0 7.3 1 1 6 8 8 8 8 Tetratricopeptide repeat TPR_6 PF13174.6 KIY63249.1 - 3.4e-24 83.8 9.5 0.0073 16.9 0.0 9.5 10 0 0 10 10 9 6 Tetratricopeptide repeat TPR_12 PF13424.6 KIY63249.1 - 1.5e-22 79.7 14.9 0.001 19.3 0.3 7.8 4 2 3 7 7 7 6 Tetratricopeptide repeat TPR_7 PF13176.6 KIY63249.1 - 2.9e-21 73.9 7.8 0.12 12.4 0.0 9.6 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_19 PF14559.6 KIY63249.1 - 4.1e-21 75.3 12.9 0.0039 17.7 0.2 6.8 4 1 3 7 7 7 7 Tetratricopeptide repeat TPR_17 PF13431.6 KIY63249.1 - 5.7e-20 70.2 11.9 0.01 16.2 0.0 9.2 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_11 PF13414.6 KIY63249.1 - 1.4e-18 66.3 26.4 3.4e-06 26.7 0.4 9.5 6 3 4 10 10 10 6 TPR repeat TPR_9 PF13371.6 KIY63249.1 - 2.1e-15 56.6 5.7 0.011 15.9 0.0 6.0 2 1 5 7 7 7 6 Tetratricopeptide repeat ANAPC3 PF12895.7 KIY63249.1 - 5.2e-10 39.4 8.6 0.00017 21.8 2.0 4.3 4 0 0 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 KIY63249.1 - 1.7e-09 37.3 5.7 0.046 12.9 2.7 5.5 1 1 6 7 7 7 4 Tetratricopeptide repeat SNAP PF14938.6 KIY63249.1 - 2.6e-07 30.4 3.0 0.095 12.1 0.1 4.0 2 2 2 4 4 4 3 Soluble NSF attachment protein, SNAP TPR_21 PF09976.9 KIY63249.1 - 5e-07 29.6 6.5 0.021 14.6 0.1 3.8 4 1 0 4 4 4 2 Tetratricopeptide repeat-like domain TPR_20 PF14561.6 KIY63249.1 - 3e-05 24.3 1.0 0.27 11.6 0.2 3.3 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KIY63249.1 - 3.1e-05 23.5 0.3 0.0039 16.6 0.0 2.4 1 1 0 2 2 2 1 MalT-like TPR region DUF2225 PF09986.9 KIY63249.1 - 0.019 14.7 2.4 3 7.5 0.0 3.2 3 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_3 PF07720.12 KIY63249.1 - 0.18 11.8 21.5 0.93 9.6 0.5 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 KIY63249.1 - 0.76 9.7 13.1 41 4.2 0.0 6.8 7 0 0 7 7 7 0 Tetratricopeptide repeat Sel1 PF08238.12 KIY63249.1 - 8.9 7.2 7.2 20 6.0 0.0 3.9 4 0 0 4 4 3 0 Sel1 repeat RTC4 PF14474.6 KIY63250.1 - 7.2e-15 55.2 0.0 1.4e-14 54.3 0.0 1.4 1 0 0 1 1 1 1 RTC4-like domain CCDC14 PF15254.6 KIY63250.1 - 0.23 10.1 0.9 0.4 9.3 0.9 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 14 Plavaka PF18759.1 KIY63252.1 - 1e-41 143.2 0.0 1.7e-41 142.5 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase Ntox35 PF15534.6 KIY63252.1 - 0.49 10.9 4.6 0.32 11.5 1.1 2.2 2 0 0 2 2 2 0 Bacterial toxin 35 zf-C2H2_4 PF13894.6 KIY63252.1 - 1 10.4 2.8 4.5 8.4 2.8 2.1 1 0 0 1 1 1 0 C2H2-type zinc finger DUF4407 PF14362.6 KIY63253.1 - 0.11 11.9 4.3 0.15 11.4 4.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 KIY63253.1 - 0.15 10.9 4.9 0.23 10.3 4.9 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF1759 PF03564.15 KIY63253.1 - 0.31 11.0 0.5 0.55 10.2 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1759) DUF724 PF05266.14 KIY63253.1 - 0.67 9.7 4.9 1.1 9.1 4.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) tRNA-synt_1 PF00133.22 KIY63254.1 - 5.1e-36 124.1 0.1 2.7e-26 92.0 0.0 3.2 3 1 0 3 3 3 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KIY63254.1 - 4.6e-17 62.4 0.9 8e-17 61.6 0.1 1.8 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KIY63254.1 - 5.9e-15 54.9 0.1 2.9e-07 29.6 0.0 2.6 3 0 0 3 3 3 2 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 KIY63254.1 - 4.3e-07 29.6 0.0 1.3e-06 28.0 0.0 1.8 1 1 1 2 2 2 1 tRNA synthetases class I (C) catalytic domain Alpha-amylase PF00128.24 KIY63256.1 - 1.3e-35 123.6 0.0 1.8e-35 123.1 0.0 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.11 KIY63256.1 - 6.6e-11 42.3 0.0 1.3e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) Acyl-CoA_dh_M PF02770.19 KIY63257.1 - 0.00033 20.8 0.0 0.00065 19.9 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cauli_VI PF01693.16 KIY63260.1 - 3.2e-11 43.3 0.0 0.00014 22.1 0.0 2.5 2 0 0 2 2 2 2 Caulimovirus viroplasmin DUF2255 PF10012.9 KIY63260.1 - 0.046 13.9 0.1 0.092 12.9 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2255) KDZ PF18758.1 KIY63263.1 - 7e-46 156.6 0.1 1.3e-45 155.7 0.1 1.5 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KIY63263.1 - 3.2e-29 101.2 0.0 1.5e-28 99.1 0.0 2.1 2 0 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases Enkurin PF13864.6 KIY63263.1 - 2.7 8.5 7.6 1.4 9.4 0.8 3.1 3 0 0 3 3 3 0 Calmodulin-binding Peptidase_S31 PF05578.12 KIY63264.1 - 0.19 11.2 0.0 0.32 10.5 0.0 1.3 1 0 0 1 1 1 0 Pestivirus NS3 polyprotein peptidase S31 PIF1 PF05970.14 KIY63265.1 - 2.8e-09 36.6 0.0 3.1e-09 36.5 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KIY63265.1 - 8e-09 35.5 0.0 9.5e-09 35.2 0.0 1.0 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KIY63265.1 - 1.7e-05 25.2 0.0 2.5e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KIY63265.1 - 0.0014 19.0 0.0 0.0066 16.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KIY63265.1 - 0.029 14.1 0.6 0.39 10.4 0.6 2.0 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA PF00004.29 KIY63265.1 - 0.087 13.3 0.1 0.13 12.7 0.1 1.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KIY63265.1 - 0.21 12.0 0.1 0.33 11.3 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_11 PF13086.6 KIY63265.1 - 0.22 11.3 0.1 2.5 7.8 0.0 2.0 1 1 1 2 2 2 0 AAA domain Helitron_like_N PF14214.6 KIY63267.1 - 5.4e-21 75.7 0.1 6.6e-21 75.4 0.1 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Vpu PF00558.19 KIY63267.1 - 0.0057 16.4 0.1 0.0097 15.7 0.1 1.3 1 0 0 1 1 1 1 Vpu protein Phlebovirus_NSM PF07246.11 KIY63267.1 - 0.034 13.5 0.4 0.053 12.9 0.3 1.3 1 1 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DUF3347 PF11827.8 KIY63267.1 - 0.11 12.6 0.1 0.16 12.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) Colicin_D PF11429.8 KIY63270.1 - 0.059 13.8 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 Colicin D F-box-like PF12937.7 KIY63276.1 - 9.6e-09 35.0 2.7 3.3e-08 33.3 2.7 2.0 1 0 0 1 1 1 1 F-box-like CRAL_TRIO_2 PF13716.6 KIY63276.1 - 0.024 14.8 0.0 0.046 13.9 0.0 1.4 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain F-box PF00646.33 KIY63276.1 - 0.076 12.9 0.5 0.26 11.2 0.5 2.0 1 0 0 1 1 1 0 F-box domain MMACHC PF16690.5 KIY63276.1 - 0.18 11.5 0.0 0.33 10.6 0.0 1.4 1 0 0 1 1 1 0 Methylmalonic aciduria and homocystinuria type C family Pkinase_fungal PF17667.1 KIY63277.1 - 1.5e-21 76.6 0.0 1.9e-21 76.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KIY63277.1 - 4.2e-05 23.6 0.3 0.00017 21.6 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 KIY63277.1 - 0.0032 16.9 0.0 0.0054 16.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 KIY63277.1 - 0.011 15.4 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 KIY63277.1 - 0.014 14.8 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family EcKinase PF02958.20 KIY63277.1 - 0.064 12.6 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase SAP PF02037.27 KIY63277.1 - 0.15 11.8 0.1 0.33 10.7 0.1 1.6 1 0 0 1 1 1 0 SAP domain Pkinase_fungal PF17667.1 KIY63278.1 - 4.4e-05 22.4 0.0 4.4e-05 22.4 0.0 1.0 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 KIY63278.1 - 0.00091 18.9 0.0 0.0011 18.6 0.0 1.1 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KIY63278.1 - 0.033 14.1 0.0 0.033 14.1 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 KIY63278.1 - 0.077 12.6 0.0 0.086 12.4 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase PF00069.25 KIY63278.1 - 0.096 12.0 0.0 0.096 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain Kdo PF06293.14 KIY63278.1 - 0.16 11.3 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KIY63281.1 - 1.5e-44 152.4 0.0 2.4e-31 108.9 0.0 2.1 1 1 1 2 2 2 2 Fungal protein kinase Pkinase PF00069.25 KIY63281.1 - 0.00012 21.6 0.0 0.00024 20.5 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 KIY63281.1 - 0.0013 18.7 0.0 0.0035 17.3 0.0 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family Macoilin PF09726.9 KIY63285.1 - 0.0054 15.4 7.9 0.014 14.0 7.9 1.6 1 1 0 1 1 1 1 Macoilin family THOC7 PF05615.13 KIY63285.1 - 0.011 16.0 0.1 0.019 15.2 0.1 1.3 1 0 0 1 1 1 0 Tho complex subunit 7 DUF5521 PF17659.1 KIY63285.1 - 0.19 9.6 1.0 0.34 8.7 1.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5521) zinc_ribbon_10 PF10058.9 KIY63287.1 - 8.7e-17 60.6 0.7 1.6e-16 59.7 0.7 1.5 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein Mu-like_Com PF10122.9 KIY63287.1 - 0.11 12.0 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Mu-like prophage protein Com Melibiase_2 PF16499.5 KIY63288.1 - 4.2e-28 98.3 1.3 1.3e-26 93.5 1.3 2.2 1 1 0 1 1 1 1 Alpha galactosidase A Melibiase PF02065.18 KIY63288.1 - 0.0019 17.2 0.0 0.003 16.5 0.0 1.2 1 0 0 1 1 1 1 Melibiase TrkH PF02386.16 KIY63289.1 - 2e-110 369.6 9.9 5.8e-108 361.5 6.2 2.1 2 0 0 2 2 2 2 Cation transport protein Upf2 PF04050.14 KIY63289.1 - 0.039 14.7 0.8 0.34 11.6 0.2 2.3 2 0 0 2 2 2 0 Up-frameshift suppressor 2 Wzy_C PF04932.15 KIY63289.1 - 0.091 12.4 0.8 0.2 11.3 0.6 1.7 1 1 0 1 1 1 0 O-Antigen ligase PEP_mutase PF13714.6 KIY63290.1 - 2.1e-44 151.8 2.5 2.6e-44 151.5 2.5 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 KIY63290.1 - 1.1e-18 67.1 0.6 1.5e-18 66.6 0.6 1.1 1 0 0 1 1 1 1 Isocitrate lyase family PEP_hydrolase PF09370.10 KIY63290.1 - 0.061 12.5 0.1 0.14 11.3 0.1 1.7 1 0 0 1 1 1 0 Phosphoenolpyruvate hydrolase-like FMN_dh PF01070.18 KIY63291.1 - 6.1e-121 403.7 0.1 7.2e-121 403.4 0.1 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KIY63291.1 - 1e-19 70.5 0.0 2.2e-19 69.4 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 KIY63291.1 - 0.00014 21.1 0.0 0.00022 20.5 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KIY63291.1 - 0.0015 17.6 0.0 0.0023 17.0 0.0 1.2 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain ABC_tran PF00005.27 KIY63292.1 - 2.8e-47 160.7 0.0 3.7e-28 98.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KIY63292.1 - 6.3e-37 127.7 19.7 1.2e-28 100.5 2.1 3.8 2 1 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 KIY63292.1 - 1.9e-07 30.8 3.5 0.022 14.2 1.4 4.0 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KIY63292.1 - 8e-06 26.2 0.3 0.28 11.4 0.1 3.5 2 1 0 2 2 2 2 AAA domain AAA_23 PF13476.6 KIY63292.1 - 3.2e-05 24.5 1.2 0.042 14.3 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KIY63292.1 - 6.3e-05 22.6 1.6 0.083 12.6 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 KIY63292.1 - 0.00066 19.1 0.0 1.3 8.3 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_16 PF13191.6 KIY63292.1 - 0.016 15.6 0.3 4.6 7.6 0.0 2.9 2 1 0 2 2 2 0 AAA ATPase domain T2SSE PF00437.20 KIY63292.1 - 0.024 13.7 0.0 2.1 7.3 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF87 PF01935.17 KIY63292.1 - 0.044 13.9 1.2 0.14 12.2 0.1 2.4 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_25 PF13481.6 KIY63292.1 - 0.061 12.9 0.0 6.1 6.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 KIY63292.1 - 0.24 11.1 0.1 9.7 5.8 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain ATPase PF06745.13 KIY63292.1 - 0.26 10.6 1.0 19 4.5 0.0 2.3 2 0 0 2 2 2 0 KaiC DEAD PF00270.29 KIY63292.1 - 0.36 10.6 1.3 14 5.4 0.7 3.1 2 1 0 2 2 2 0 DEAD/DEAH box helicase ABC_tran PF00005.27 KIY63293.1 - 7.8e-47 159.2 0.0 1.1e-28 100.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KIY63293.1 - 1.4e-44 152.8 25.5 5.8e-29 101.6 1.7 3.7 4 0 0 4 4 4 2 ABC transporter transmembrane region SMC_N PF02463.19 KIY63293.1 - 4e-08 33.0 0.8 0.0074 15.8 1.9 4.0 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KIY63293.1 - 0.0002 21.0 1.5 0.082 12.7 0.2 2.9 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KIY63293.1 - 0.0016 19.0 0.2 2.6 8.5 0.2 2.4 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KIY63293.1 - 0.0036 17.6 0.5 4.9 7.4 0.2 3.4 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KIY63293.1 - 0.0049 16.5 0.0 0.54 9.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 KIY63293.1 - 0.01 15.2 0.4 1.3 8.3 0.0 2.4 2 0 0 2 2 2 0 KaiC T2SSE PF00437.20 KIY63293.1 - 0.021 13.9 0.0 1.6 7.7 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 KIY63293.1 - 0.026 13.9 0.0 1.2 8.4 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF87 PF01935.17 KIY63293.1 - 0.05 13.7 0.1 0.14 12.2 0.1 1.7 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_16 PF13191.6 KIY63293.1 - 0.069 13.5 0.5 1.4 9.2 0.0 2.9 3 1 0 3 3 3 0 AAA ATPase domain DEAD PF00270.29 KIY63293.1 - 0.43 10.3 1.6 18 5.1 1.0 3.2 2 1 0 2 2 2 0 DEAD/DEAH box helicase Claudin_2 PF13903.6 KIY63294.1 - 0.048 13.4 2.7 0.35 10.6 0.7 2.3 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction AAA_32 PF13654.6 KIY63294.1 - 0.18 10.6 0.0 0.23 10.2 0.0 1.1 1 0 0 1 1 1 0 AAA domain DegQ PF08181.11 KIY63295.1 - 0.082 13.0 0.2 0.25 11.5 0.1 1.8 2 0 0 2 2 2 0 DegQ (SacQ) family FANC_SAP PF18081.1 KIY63295.1 - 0.1 12.8 0.3 7 6.9 0.1 2.5 2 0 0 2 2 2 0 Fanconi anemia-associated nuclease SAP domain Acyltransferase PF01553.21 KIY63295.1 - 0.17 11.5 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 Acyltransferase zf-MYND PF01753.18 KIY63297.1 - 6e-11 42.3 12.8 6e-11 42.3 12.8 2.1 2 0 0 2 2 2 1 MYND finger zf-Mss51 PF13824.6 KIY63297.1 - 0.0031 17.6 6.2 0.0088 16.1 6.2 1.7 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-C6H2 PF15801.5 KIY63297.1 - 0.13 12.6 12.2 0.054 13.8 9.2 2.0 2 1 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding PHD PF00628.29 KIY63297.1 - 0.14 12.1 14.7 1.4 8.9 0.3 2.7 2 1 0 2 2 2 0 PHD-finger zf-MYND PF01753.18 KIY63298.1 - 3.5e-08 33.4 12.4 3.5e-08 33.4 12.4 2.6 3 0 0 3 3 3 1 MYND finger zf-Mss51 PF13824.6 KIY63298.1 - 0.097 12.8 6.2 0.25 11.4 6.2 1.7 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-Sec23_Sec24 PF04810.15 KIY63298.1 - 0.53 10.4 0.2 0.53 10.4 0.2 3.3 3 1 0 3 3 3 0 Sec23/Sec24 zinc finger PHD PF00628.29 KIY63298.1 - 5.2 7.0 16.4 8 6.4 0.1 3.0 3 1 0 3 3 3 0 PHD-finger Glyco_hydro_43 PF04616.14 KIY63299.1 - 7.5e-42 143.6 2.0 9.2e-42 143.3 2.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 SE PF08491.10 KIY63300.1 - 5.7e-92 307.7 0.0 7.7e-92 307.2 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 KIY63300.1 - 5.1e-14 52.3 0.0 7.1e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KIY63300.1 - 1.6e-12 47.7 0.1 3e-05 23.8 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KIY63300.1 - 4.4e-08 32.4 0.8 0.03 13.2 0.1 3.1 2 1 0 3 3 3 3 Tryptophan halogenase FAD_binding_2 PF00890.24 KIY63300.1 - 1.2e-06 27.9 0.3 0.0081 15.3 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 KIY63300.1 - 5.9e-06 25.6 0.2 0.001 18.2 0.1 2.5 2 1 1 3 3 3 2 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KIY63300.1 - 6.2e-06 25.6 0.0 2.1e-05 23.9 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KIY63300.1 - 1.3e-05 24.5 0.2 2e-05 23.9 0.2 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.17 KIY63300.1 - 0.00034 19.9 0.1 0.0012 18.1 0.0 1.8 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 KIY63300.1 - 0.00037 21.0 0.2 0.05 14.2 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIY63300.1 - 0.00052 20.2 0.0 0.0011 19.2 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GMC_oxred_N PF00732.19 KIY63300.1 - 0.0049 16.3 0.2 2.2 7.6 0.1 2.2 2 0 0 2 2 2 2 GMC oxidoreductase Pyr_redox_3 PF13738.6 KIY63300.1 - 0.011 15.0 0.1 0.52 9.5 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KIY63300.1 - 0.024 14.6 0.2 0.17 11.9 0.1 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding Mqo PF06039.15 KIY63300.1 - 0.19 10.2 0.0 0.37 9.3 0.0 1.4 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) dCMP_cyt_deam_1 PF00383.23 KIY63301.1 - 5.4e-17 61.5 0.1 7.1e-17 61.2 0.1 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 KIY63301.1 - 2.7e-14 53.5 3.0 1e-12 48.4 0.3 2.1 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 KIY63301.1 - 0.012 15.2 0.8 0.22 11.1 0.1 2.1 1 1 1 2 2 2 0 A distinct subfamily of CDD/CDA-like deaminases HARP PF07443.13 KIY63301.1 - 0.18 11.4 0.0 0.33 10.6 0.0 1.3 1 0 0 1 1 1 0 HepA-related protein (HARP) tRNA-synt_2b PF00587.25 KIY63302.1 - 2.3e-39 135.2 0.0 4.1e-39 134.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KIY63302.1 - 2e-19 69.5 0.5 5.2e-19 68.2 0.1 2.0 3 0 0 3 3 3 1 Anticodon binding domain TGS PF02824.21 KIY63302.1 - 1.9e-13 50.2 0.0 8.1e-13 48.2 0.0 2.1 2 0 0 2 2 2 1 TGS domain tRNA_SAD PF07973.14 KIY63302.1 - 3.6e-10 39.8 0.0 6.8e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain p450 PF00067.22 KIY63303.1 - 6e-76 256.0 0.0 8.8e-76 255.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hyd_65N_2 PF14498.6 KIY63304.1 - 2.7e-45 155.1 0.0 4.2e-45 154.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Dynamin_N PF00350.23 KIY63305.1 - 1.6e-19 70.6 0.1 3.5e-18 66.2 0.0 2.9 3 0 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.23 KIY63305.1 - 2.4e-12 46.9 0.0 1.3e-11 44.6 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KIY63305.1 - 2.1e-08 33.9 0.4 2.6e-07 30.4 0.4 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KIY63305.1 - 0.00025 21.0 1.2 0.14 12.1 0.2 2.9 2 1 0 2 2 2 2 RsgA GTPase cobW PF02492.19 KIY63305.1 - 0.001 18.7 0.4 0.12 12.0 0.1 2.7 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 KIY63305.1 - 0.015 15.5 0.0 1.9 8.7 0.0 3.1 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase TsaE PF02367.17 KIY63305.1 - 0.019 15.0 0.1 0.054 13.5 0.0 1.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IIGP PF05049.13 KIY63305.1 - 0.028 13.5 0.0 0.058 12.4 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) GOLGA2L5 PF15070.6 KIY63305.1 - 0.042 12.5 3.8 0.099 11.3 0.1 2.3 2 0 0 2 2 2 0 Putative golgin subfamily A member 2-like protein 5 AAA_29 PF13555.6 KIY63305.1 - 0.053 13.3 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Brix PF04427.18 KIY63306.1 - 1.2e-39 136.4 0.1 1.7e-39 135.9 0.1 1.2 1 0 0 1 1 1 1 Brix domain p450 PF00067.22 KIY63307.1 - 5.4e-63 213.3 0.0 1e-62 212.4 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Abhydrolase_6 PF12697.7 KIY63308.1 - 5.1e-12 46.9 1.3 2.6e-11 44.6 0.4 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIY63308.1 - 2.4e-11 43.3 0.2 5.5e-10 38.9 0.1 2.3 1 1 2 3 3 3 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KIY63308.1 - 3.7e-11 43.2 0.1 2.5e-10 40.4 0.1 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 KIY63308.1 - 7.5e-08 32.5 0.1 1.3e-07 31.7 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KIY63308.1 - 5.2e-05 22.8 0.0 0.00014 21.4 0.0 1.8 1 1 1 2 2 2 1 Prolyl oligopeptidase family DUF818 PF05677.12 KIY63308.1 - 0.0012 17.9 0.0 0.0017 17.4 0.0 1.2 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Chlorophyllase2 PF12740.7 KIY63308.1 - 0.0032 16.4 0.1 0.033 13.1 0.1 2.0 1 1 0 1 1 1 1 Chlorophyllase enzyme LIDHydrolase PF10230.9 KIY63308.1 - 0.01 15.4 0.0 0.021 14.4 0.0 1.6 1 1 0 1 1 1 0 Lipid-droplet associated hydrolase DUF3089 PF11288.8 KIY63308.1 - 0.018 14.6 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Ser_hydrolase PF06821.13 KIY63308.1 - 0.02 14.7 0.0 0.035 13.9 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase Thioesterase PF00975.20 KIY63308.1 - 0.046 13.8 0.0 0.08 13.0 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain DLH PF01738.18 KIY63308.1 - 0.052 13.1 0.0 10 5.6 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family FMP23 PF17315.2 KIY63308.1 - 0.092 12.9 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Found in mitochondrial proteome Lipase_3 PF01764.25 KIY63308.1 - 0.14 12.0 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) FSH1 PF03959.13 KIY63308.1 - 0.19 11.4 0.0 1.7 8.3 0.0 2.1 1 1 0 2 2 2 0 Serine hydrolase (FSH1) Mito_carr PF00153.27 KIY63309.1 - 1.3e-57 191.7 2.6 2.5e-20 72.2 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein HMD PF03201.16 KIY63309.1 - 0.096 12.9 0.2 2.5 8.4 0.1 2.3 2 0 0 2 2 2 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase COX17 PF05051.13 KIY63310.1 - 3.8e-22 78.4 4.4 4.6e-22 78.1 4.4 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Ribosomal_L14e PF01929.17 KIY63311.1 - 7.4e-31 106.5 0.5 1.1e-30 106.0 0.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 KIY63311.1 - 2.9e-06 27.0 2.6 6.3e-05 22.8 0.2 2.3 2 0 0 2 2 2 2 KOW motif DFRP_C PF16543.5 KIY63312.1 - 2.9e-28 98.2 3.8 2.9e-28 98.2 3.8 4.3 2 2 2 4 4 4 1 DRG Family Regulatory Proteins, Tma46 zf-CCCH_4 PF18044.1 KIY63312.1 - 1e-06 28.4 9.2 0.00024 20.8 2.2 3.2 3 0 0 3 3 3 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KIY63312.1 - 1.2e-06 28.3 17.7 6.8e-05 22.8 6.6 3.1 3 0 0 3 3 3 2 Zinc finger domain zf-CCCH PF00642.24 KIY63312.1 - 0.00019 21.2 1.5 0.00019 21.2 1.5 2.6 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KIY63312.1 - 0.00056 20.6 20.0 0.0025 18.5 4.7 3.9 3 1 1 4 4 4 2 Torus domain zf-CCCH_2 PF14608.6 KIY63312.1 - 0.0011 19.3 10.8 0.16 12.5 0.6 2.8 2 1 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 KIY63312.1 - 0.0036 17.5 3.8 0.18 12.0 0.2 2.9 3 0 0 3 3 3 2 Zinc-finger containing family Inhibitor_I36 PF03995.13 KIY63312.1 - 0.16 11.9 0.5 17 5.5 0.0 2.4 2 0 0 2 2 2 0 Peptidase inhibitor family I36 Ndc1_Nup PF09531.10 KIY63312.1 - 6.9 5.2 5.2 0.68 8.6 0.4 1.6 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup NuDC PF16273.5 KIY63313.1 - 2.1 8.9 12.0 0.92 10.1 0.1 2.3 2 0 0 2 2 2 0 Nuclear distribution C domain HSF_DNA-bind PF00447.17 KIY63316.1 - 5.4e-30 103.9 0.3 9.2e-30 103.1 0.3 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding Ets PF00178.22 KIY63316.1 - 0.1 13.1 0.1 0.21 12.1 0.1 1.5 1 0 0 1 1 1 0 Ets-domain Nup88 PF10168.9 KIY63316.1 - 0.15 9.9 0.1 0.22 9.3 0.1 1.1 1 0 0 1 1 1 0 Nuclear pore component WXG100 PF06013.12 KIY63316.1 - 1.3 9.3 4.2 4.6 7.5 1.5 2.7 2 1 0 2 2 2 0 Proteins of 100 residues with WXG LPD30 PF18850.1 KIY63318.1 - 0.23 11.3 2.4 0.27 11.0 2.4 1.1 1 0 0 1 1 1 0 Large polyvalent protein associated domain 30 ATP-synt_E PF05680.12 KIY63318.1 - 0.77 10.1 7.9 0.88 9.9 7.9 1.2 1 0 0 1 1 1 0 ATP synthase E chain Astro_capsid_p PF12226.8 KIY63318.1 - 1.1 8.3 8.2 1 8.4 8.2 1.0 1 0 0 1 1 1 0 Turkey astrovirus capsid protein RNA_pol_3_Rpc31 PF11705.8 KIY63318.1 - 1.6 8.9 17.6 1.7 8.8 17.6 1.0 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 VIR_N PF15912.5 KIY63318.1 - 2 7.9 10.9 2.1 7.9 10.9 1.0 1 0 0 1 1 1 0 Virilizer, N-terminal TFB6 PF17110.5 KIY63318.1 - 2.4 7.9 6.8 2.4 7.9 6.8 1.0 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH DUF1682 PF07946.14 KIY63318.1 - 4 6.6 14.1 4.7 6.3 14.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Peptidase_S49_N PF08496.10 KIY63318.1 - 5 7.2 7.0 5.5 7.0 7.0 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Presenilin PF01080.17 KIY63318.1 - 5.7 5.6 4.3 5.2 5.7 4.3 1.0 1 0 0 1 1 1 0 Presenilin DUF3464 PF11947.8 KIY63318.1 - 6 6.6 8.9 7.3 6.3 8.9 1.1 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 LAT PF15234.6 KIY63319.1 - 0.1 12.3 2.6 0.2 11.4 2.6 1.4 1 0 0 1 1 1 0 Linker for activation of T-cells Big_3_4 PF13754.6 KIY63319.1 - 0.19 11.5 0.0 0.34 10.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function NuDC PF16273.5 KIY63319.1 - 0.45 11.1 13.8 1.6 9.3 0.0 2.3 2 0 0 2 2 2 0 Nuclear distribution C domain CENP-B_dimeris PF09026.10 KIY63319.1 - 0.6 10.5 9.9 0.68 10.4 7.8 1.9 2 0 0 2 2 2 0 Centromere protein B dimerisation domain NOA36 PF06524.12 KIY63319.1 - 0.89 8.8 4.7 1.2 8.4 4.7 1.2 1 0 0 1 1 1 0 NOA36 protein FAM176 PF14851.6 KIY63319.1 - 2.3 7.9 4.5 0.79 9.4 0.8 1.9 2 0 0 2 2 2 0 FAM176 family Isochorismatase PF00857.20 KIY63320.1 - 2.5e-13 50.6 0.0 5.3e-13 49.5 0.0 1.5 1 1 0 1 1 1 1 Isochorismatase family IMUP PF15761.5 KIY63322.1 - 0.48 11.1 3.8 0.86 10.3 3.8 1.4 1 0 0 1 1 1 0 Immortalisation up-regulated protein T_cell_tran_alt PF15128.6 KIY63322.1 - 1.2 9.0 2.9 0.79 9.6 0.8 1.7 2 0 0 2 2 2 0 T-cell leukemia translocation-altered CNDH2_M PF16869.5 KIY63324.1 - 0.16 12.6 1.0 7.5 7.2 0.1 2.2 2 0 0 2 2 2 0 PF16858 SDA1 PF05285.12 KIY63326.1 - 7.8 5.8 30.8 13 5.0 30.8 1.3 1 0 0 1 1 1 0 SDA1 Ytp1 PF10355.9 KIY63328.1 - 3e-57 193.9 21.3 1.4e-55 188.5 21.3 2.3 1 1 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 KIY63328.1 - 6.9e-28 96.5 1.1 6.9e-28 96.5 1.1 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) Cytochrom_B561 PF03188.16 KIY63328.1 - 0.00084 19.5 6.3 0.00084 19.5 6.3 3.6 4 2 0 4 4 4 1 Eukaryotic cytochrome b561 PNTB PF02233.16 KIY63328.1 - 0.39 9.6 7.7 0.68 8.8 1.5 2.4 1 1 0 2 2 2 0 NAD(P) transhydrogenase beta subunit Lipase_3 PF01764.25 KIY63329.1 - 8.3e-22 77.6 0.0 1.6e-21 76.7 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KIY63329.1 - 0.0012 19.5 3.1 0.0012 19.5 3.1 1.7 1 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KIY63329.1 - 0.014 15.1 0.0 0.018 14.7 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Lipase_3 PF01764.25 KIY63330.1 - 2.2e-22 79.4 0.0 3.4e-22 78.8 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KIY63330.1 - 0.0089 16.7 3.2 0.0092 16.6 1.9 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KIY63330.1 - 0.011 15.4 0.1 0.016 14.9 0.1 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIY63330.1 - 0.016 14.4 0.2 0.027 13.8 0.2 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF1459 PF07312.11 KIY63330.1 - 0.16 12.2 2.2 0.29 11.4 2.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1459) Cellulase PF00150.18 KIY63331.1 - 1.6e-11 44.2 0.0 2.4e-11 43.6 0.0 1.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) LRR_4 PF12799.7 KIY63334.1 - 2 9.0 7.4 0.29 11.6 0.9 2.9 2 2 1 3 3 3 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KIY63335.1 - 1.1e-08 34.8 0.2 4.2e-08 33.0 0.2 2.0 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KIY63335.1 - 6.1e-05 23.3 2.8 0.57 10.7 0.1 4.4 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) F-box-like_2 PF13013.6 KIY63335.1 - 0.1 12.6 0.1 0.24 11.4 0.1 1.6 1 0 0 1 1 1 0 F-box-like domain WAPL PF07814.13 KIY63336.1 - 1.1e-11 44.1 8.4 3.5e-09 35.9 5.5 3.6 2 1 0 2 2 2 2 Wings apart-like protein regulation of heterochromatin VGLL4 PF15245.6 KIY63336.1 - 0.28 11.2 3.6 0.33 11.0 0.0 2.2 2 0 0 2 2 2 0 Transcription cofactor vestigial-like protein 4 DUF4598 PF15370.6 KIY63337.1 - 8e-19 68.2 0.1 1.7e-18 67.1 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4598) F-box-like PF12937.7 KIY63338.1 - 0.0003 20.6 0.5 0.001 18.9 0.2 2.1 2 0 0 2 2 2 1 F-box-like F-box-like_2 PF13013.6 KIY63338.1 - 0.0045 16.9 0.0 0.01 15.8 0.0 1.5 1 0 0 1 1 1 1 F-box-like domain LRR_4 PF12799.7 KIY63338.1 - 0.17 12.4 6.5 0.87 10.1 0.3 4.3 4 3 1 5 5 5 0 Leucine Rich repeats (2 copies) Tropomyosin_1 PF12718.7 KIY63338.1 - 0.18 12.0 0.0 0.28 11.3 0.0 1.2 1 0 0 1 1 1 0 Tropomyosin like F-box-like PF12937.7 KIY63339.1 - 1.7e-08 34.2 4.0 1.7e-08 34.2 4.0 2.2 1 1 0 1 1 1 1 F-box-like F-box-like_2 PF13013.6 KIY63339.1 - 0.0032 17.4 0.1 0.0046 16.9 0.1 1.4 1 0 0 1 1 1 1 F-box-like domain TMF_TATA_bd PF12325.8 KIY63339.1 - 0.021 15.0 0.0 0.028 14.6 0.0 1.1 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding PI3K_P85_iSH2 PF16454.5 KIY63339.1 - 0.025 14.2 0.0 0.032 13.8 0.0 1.1 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain F-box PF00646.33 KIY63339.1 - 0.04 13.8 0.7 4.4 7.3 0.1 2.4 2 0 0 2 2 2 0 F-box domain DUF5082 PF16888.5 KIY63339.1 - 0.084 13.2 0.1 0.12 12.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) F-box-like PF12937.7 KIY63340.1 - 1.2e-07 31.4 1.2 3.9e-07 29.9 1.2 1.9 1 1 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KIY63340.1 - 0.00022 21.5 4.9 0.27 11.7 0.1 4.6 5 2 0 5 5 5 2 Leucine Rich repeats (2 copies) Glyco_hydro_79n PF03662.14 KIY63340.1 - 0.044 12.7 0.0 0.067 12.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 79, N-terminal domain F-box-like_2 PF13013.6 KIY63340.1 - 0.044 13.8 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 F-box-like domain MFS_1 PF07690.16 KIY63341.1 - 7.9e-47 159.9 32.9 2.1e-42 145.3 21.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3367 PF11847.8 KIY63341.1 - 0.0066 14.4 2.7 0.01 13.7 2.7 1.2 1 0 0 1 1 1 1 Alpha-(1->3)-arabinofuranosyltransferase FixP_N PF14715.6 KIY63341.1 - 9.2 6.1 7.3 4.5 7.1 1.6 3.1 2 0 0 2 2 2 0 N-terminal domain of cytochrome oxidase-cbb3, FixP F-box PF00646.33 KIY63342.1 - 0.0057 16.5 0.0 0.014 15.3 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KIY63342.1 - 0.011 15.6 0.0 0.032 14.1 0.0 1.8 1 0 0 1 1 1 0 F-box-like NAD_kinase PF01513.21 KIY63344.1 - 5.7e-72 242.4 0.0 1.3e-71 241.2 0.0 1.7 1 1 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 KIY63344.1 - 0.14 11.7 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain NOA36 PF06524.12 KIY63344.1 - 0.42 9.9 3.2 0.73 9.1 3.2 1.3 1 0 0 1 1 1 0 NOA36 protein YqeY PF09424.10 KIY63345.1 - 3e-28 98.7 1.9 3.7e-28 98.4 1.9 1.1 1 0 0 1 1 1 1 Yqey-like protein RecC_C PF17946.1 KIY63345.1 - 0.08 12.7 0.4 0.12 12.2 0.4 1.3 1 1 0 1 1 1 0 RecC C-terminal domain DUF1974 PF09317.11 KIY63345.1 - 0.1 12.1 0.5 0.18 11.3 0.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1974) Q_salvage PF10343.9 KIY63346.1 - 5.8e-11 42.5 0.0 6.1e-08 32.6 0.0 2.3 2 0 0 2 2 2 2 Potential Queuosine, Q, salvage protein family NIF PF03031.18 KIY63347.1 - 1e-40 139.0 0.0 1.6e-40 138.4 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase GPI-anchored PF10342.9 KIY63348.1 - 2e-07 31.7 0.2 3.1e-07 31.1 0.2 1.3 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family TPR_2 PF07719.17 KIY63349.1 - 8.5e-13 47.4 6.5 0.089 12.9 0.0 7.6 8 0 0 8 8 8 2 Tetratricopeptide repeat ANAPC8 PF04049.13 KIY63349.1 - 2.9e-10 40.4 0.2 2.7e-07 30.7 0.2 2.3 1 1 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_14 PF13428.6 KIY63349.1 - 1.2e-09 38.2 9.9 0.07 14.0 0.0 7.2 5 1 2 7 7 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 KIY63349.1 - 1.1e-07 31.4 0.6 0.43 10.9 0.0 5.8 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 KIY63349.1 - 1.3e-06 28.9 11.7 0.85 10.3 0.4 6.3 4 1 2 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 KIY63349.1 - 9.3e-06 25.3 3.1 0.18 11.7 0.1 5.4 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 KIY63349.1 - 9.6e-05 22.8 4.7 0.76 10.3 0.0 5.5 4 2 1 5 5 5 1 Tetratricopeptide repeat BTAD PF03704.17 KIY63349.1 - 0.097 13.1 6.0 1.2 9.6 0.0 3.8 5 1 0 5 5 4 0 Bacterial transcriptional activator domain Rapsyn_N PF10579.9 KIY63349.1 - 0.11 12.6 0.0 3.6 7.8 0.0 2.5 2 0 0 2 2 2 0 Rapsyn N-terminal myristoylation and linker region ANAPC3 PF12895.7 KIY63349.1 - 0.13 12.5 9.7 13 6.1 0.1 5.2 4 1 1 5 5 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 KIY63349.1 - 0.26 11.6 14.1 7.3 7.0 0.6 5.3 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_9 PF13371.6 KIY63349.1 - 0.29 11.3 12.4 0.068 13.3 0.8 4.5 6 0 0 6 6 6 0 Tetratricopeptide repeat MPC PF03650.13 KIY63350.1 - 7.4e-40 135.5 0.1 8.4e-40 135.3 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers Tetraspanin PF00335.20 KIY63351.1 - 0.013 15.2 0.0 0.016 14.9 0.0 1.2 1 0 0 1 1 1 0 Tetraspanin family RPA_interact_C PF14768.6 KIY63352.1 - 0.0079 16.7 0.1 0.013 16.1 0.1 1.3 1 0 0 1 1 1 1 Replication protein A interacting C-terminal WD40 PF00400.32 KIY63353.1 - 5.2e-08 33.4 2.6 0.022 15.6 0.0 5.4 5 1 0 5 5 5 3 WD domain, G-beta repeat Nucleos_tra2_C PF07662.13 KIY63354.1 - 2e-68 230.3 5.8 2e-68 230.3 5.8 2.0 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 KIY63354.1 - 1.9e-19 70.0 7.1 1.9e-19 70.0 7.1 4.0 4 0 0 4 4 4 1 Na+ dependent nucleoside transporter N-terminus Mid2 PF04478.12 KIY63355.1 - 1.2e-05 25.1 0.1 2.3e-05 24.2 0.1 1.4 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor SKG6 PF08693.10 KIY63355.1 - 0.00092 18.6 1.1 0.00092 18.6 1.1 1.8 2 0 0 2 2 2 1 Transmembrane alpha-helix domain DUF2207 PF09972.9 KIY63355.1 - 0.0052 15.6 0.0 0.0073 15.1 0.0 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) CEND1 PF15677.5 KIY63355.1 - 0.0083 16.7 0.1 0.019 15.5 0.1 1.6 1 0 0 1 1 1 1 Cell cycle exit and neuronal differentiation protein 1 TMEM154 PF15102.6 KIY63355.1 - 0.024 14.6 0.1 0.024 14.6 0.1 1.6 2 0 0 2 2 2 0 TMEM154 protein family Podoplanin PF05808.11 KIY63355.1 - 0.032 14.3 0.8 0.032 14.3 0.8 1.6 2 0 0 2 2 2 0 Podoplanin Rax2 PF12768.7 KIY63355.1 - 0.033 13.6 0.0 0.05 13.1 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity DUF1180 PF06679.12 KIY63355.1 - 4.7 7.6 15.9 0.14 12.5 4.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1180) DUF3328 PF11807.8 KIY63356.1 - 0.23 11.2 0.6 1.2 8.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) Peptidase_S48 PF03574.15 KIY63358.1 - 0.042 14.1 0.1 6.4 7.0 0.0 2.2 1 1 1 2 2 2 0 Peptidase family S48 Sterol_MT_C PF08498.10 KIY63359.1 - 4.4e-22 78.2 0.0 7.2e-22 77.5 0.0 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 KIY63359.1 - 1.7e-19 70.3 0.0 4.5e-19 68.9 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIY63359.1 - 2.2e-19 69.8 0.0 3.1e-19 69.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIY63359.1 - 3.7e-17 62.8 0.1 1.1e-16 61.3 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain CMAS PF02353.20 KIY63359.1 - 4.1e-14 52.5 0.0 5.4e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 KIY63359.1 - 3.1e-13 50.3 0.1 1e-11 45.5 0.0 2.5 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIY63359.1 - 3.4e-13 49.7 0.0 8.9e-13 48.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIY63359.1 - 2.2e-09 37.0 0.0 3.7e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 KIY63359.1 - 6.2e-06 26.1 0.0 8.9e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_15 PF09445.10 KIY63359.1 - 0.00053 19.6 0.0 0.0008 19.0 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase UPF0020 PF01170.18 KIY63359.1 - 0.0007 19.3 0.0 0.0011 18.7 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 MTS PF05175.14 KIY63359.1 - 0.0012 18.4 0.0 0.002 17.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.16 KIY63359.1 - 0.0012 18.6 0.0 0.0017 18.1 0.0 1.1 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_2 PF00891.18 KIY63359.1 - 0.0014 18.0 0.1 0.0021 17.4 0.1 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_24 PF13578.6 KIY63359.1 - 0.0018 19.3 0.0 0.0055 17.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 KIY63359.1 - 0.0019 17.4 0.0 0.0029 16.8 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase MetW PF07021.12 KIY63359.1 - 0.0027 17.3 0.0 0.0038 16.8 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 KIY63359.1 - 0.016 15.2 0.0 0.027 14.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 KIY63359.1 - 0.062 12.7 0.0 0.083 12.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) NMT1 PF09084.11 KIY63359.1 - 0.11 12.4 0.2 0.25 11.3 0.0 1.6 2 0 0 2 2 2 0 NMT1/THI5 like Methyltransf_18 PF12847.7 KIY63359.1 - 0.18 11.8 0.0 0.34 10.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.17 KIY63359.1 - 0.19 11.2 0.0 0.36 10.3 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Mannosidase_ig PF17786.1 KIY63360.1 - 5.9e-14 52.5 0.3 1.5e-13 51.2 0.1 1.8 2 0 0 2 2 2 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 KIY63360.1 - 7.1e-06 26.7 0.0 2e-05 25.2 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Ig_mannosidase PF17753.1 KIY63360.1 - 1.7e-05 24.4 0.0 4.3e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Ig-fold domain Glyco_hydro_2_C PF02836.17 KIY63360.1 - 0.002 17.3 0.3 0.0073 15.4 0.3 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain 60KD_IMP PF02096.20 KIY63361.1 - 0.31 10.9 0.9 0.55 10.1 0.3 1.7 1 1 1 2 2 2 0 60Kd inner membrane protein DUF5320 PF17253.2 KIY63361.1 - 4.1 8.5 7.4 2.5 9.2 1.2 2.3 1 1 0 2 2 2 0 Family of unknown function (DUF5320) ZapB PF06005.12 KIY63361.1 - 7 7.2 13.9 2.2e+02 2.3 11.8 2.5 1 1 0 1 1 1 0 Cell division protein ZapB Ovate PF04844.13 KIY63363.1 - 0.094 12.7 0.1 0.27 11.2 0.1 1.8 1 1 0 1 1 1 0 Transcriptional repressor, ovate Mob1_phocein PF03637.17 KIY63364.1 - 3.7e-67 225.6 0.5 4.8e-67 225.2 0.5 1.1 1 0 0 1 1 1 1 Mob1/phocein family Sel1 PF08238.12 KIY63367.1 - 2.2e-19 69.5 5.3 3.9e-07 30.5 0.1 4.0 4 0 0 4 4 4 3 Sel1 repeat TPR_16 PF13432.6 KIY63367.1 - 0.014 16.0 0.0 0.064 13.9 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 KIY63367.1 - 0.016 15.2 0.6 1.6 9.0 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat dCache_1 PF02743.18 KIY63367.1 - 0.088 12.6 0.2 0.16 11.7 0.2 1.4 1 0 0 1 1 1 0 Cache domain TPR_1 PF00515.28 KIY63367.1 - 0.25 11.3 1.6 1.7 8.6 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat F-box-like PF12937.7 KIY63368.1 - 0.00021 21.1 0.2 0.00044 20.1 0.2 1.6 1 0 0 1 1 1 1 F-box-like Formyl_trans_N PF00551.19 KIY63369.1 - 1.5e-41 142.1 0.0 1.8e-41 141.9 0.0 1.0 1 0 0 1 1 1 1 Formyl transferase ArfGap PF01412.18 KIY63371.1 - 0.9 9.6 5.9 6.8 6.8 0.3 3.6 4 0 0 4 4 4 0 Putative GTPase activating protein for Arf F-box-like PF12937.7 KIY63372.1 - 5.1e-09 35.9 0.3 1.2e-08 34.7 0.3 1.7 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KIY63372.1 - 0.00038 20.8 13.4 0.62 10.6 0.0 6.3 6 2 0 6 6 6 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KIY63372.1 - 0.15 12.2 2.3 1.3 9.2 0.0 3.7 4 0 0 4 4 4 0 Leucine Rich repeat zf-MYND PF01753.18 KIY63373.1 - 4.1e-07 30.0 11.2 1e-06 28.7 11.2 1.7 1 0 0 1 1 1 1 MYND finger F-box-like PF12937.7 KIY63374.1 - 7.1e-10 38.6 1.3 1.1e-09 38.0 1.3 1.3 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY63374.1 - 0.012 15.5 4.4 0.48 10.4 0.2 2.4 2 0 0 2 2 2 0 F-box domain F-box-like_2 PF13013.6 KIY63374.1 - 0.044 13.8 0.1 0.047 13.7 0.1 1.4 1 0 0 1 1 1 0 F-box-like domain Osmo_CC PF08946.10 KIY63374.1 - 0.2 11.9 1.3 0.34 11.2 1.1 1.5 1 1 0 1 1 1 0 Osmosensory transporter coiled coil F-box-like PF12937.7 KIY63375.1 - 2.7e-09 36.8 0.5 6.5e-09 35.6 0.1 1.9 2 0 0 2 2 2 1 F-box-like Tektin PF03148.14 KIY63375.1 - 0.14 10.8 0.0 0.24 10.1 0.0 1.2 1 0 0 1 1 1 0 Tektin family LRR_4 PF12799.7 KIY63375.1 - 4.4 7.9 18.9 0.57 10.7 0.2 5.8 4 3 3 7 7 7 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KIY63377.1 - 0.0016 18.3 5.3 0.0022 17.8 3.4 2.3 2 1 0 2 2 2 1 F-box-like START PF01852.19 KIY63378.1 - 1.4e-17 63.8 0.0 1e-07 31.6 0.0 3.5 3 0 0 3 3 3 3 START domain GIDA_assoc PF13932.6 KIY63381.1 - 0.05 13.8 0.0 0.05 13.8 0.0 1.2 1 0 0 1 1 1 0 GidA associated domain zf-CCCH_4 PF18044.1 KIY63383.1 - 2.6e-07 30.3 3.9 4.6e-07 29.5 3.9 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KIY63383.1 - 1.5e-05 24.9 8.3 2.6e-05 24.1 8.3 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 KIY63383.1 - 1.6e-05 24.7 5.5 2.9e-05 23.9 5.5 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KIY63383.1 - 0.0027 18.4 0.6 0.0066 17.1 0.6 1.6 1 0 0 1 1 1 1 Torus domain zf-CCCH_2 PF14608.6 KIY63383.1 - 0.0031 17.9 6.4 0.0054 17.2 6.4 1.4 1 0 0 1 1 1 1 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 KIY63383.1 - 0.069 13.4 0.3 0.13 12.5 0.3 1.4 1 0 0 1 1 1 0 Zinc-finger containing family TAF4 PF05236.14 KIY63384.1 - 8e-34 117.6 9.1 1.2e-33 117.1 9.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family SAGA-Tad1 PF12767.7 KIY63384.1 - 0.028 14.1 1.2 0.42 10.3 0.0 2.4 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit Pkinase PF00069.25 KIY63385.1 - 9.4e-44 149.7 0.0 1.2e-43 149.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY63385.1 - 1.8e-18 66.8 0.0 2.3e-18 66.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY63385.1 - 8.9e-07 28.5 0.0 7.5e-06 25.5 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KIY63385.1 - 0.00014 20.9 0.0 0.00018 20.6 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KIY63385.1 - 0.0014 18.0 0.0 0.0026 17.1 0.0 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIY63385.1 - 0.01 15.8 0.0 3.6 7.5 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KIY63385.1 - 0.057 12.5 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Pox_ser-thr_kin PF05445.11 KIY63385.1 - 0.1 11.6 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase LSPR PF06049.12 KIY63386.1 - 4.2 7.6 6.4 2.7 8.2 2.4 2.5 2 0 0 2 2 2 0 Coagulation Factor V LSPD Repeat T3SSipB PF16535.5 KIY63387.1 - 0.032 14.7 0.6 0.039 14.4 0.6 1.1 1 0 0 1 1 1 0 Type III cell invasion protein SipB MT0933_antitox PF14013.6 KIY63387.1 - 0.052 13.8 2.6 0.14 12.5 2.6 2.0 1 1 0 1 1 1 0 MT0933-like antitoxin protein UPF0183 PF03676.14 KIY63388.1 - 0.12 11.7 0.1 0.33 10.2 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0183) ADH_zinc_N PF00107.26 KIY63389.1 - 3.8e-14 52.8 0.0 7.4e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KIY63389.1 - 9.2e-09 36.5 0.0 1.7e-08 35.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIY63389.1 - 1.5e-08 34.5 0.1 7.9e-08 32.2 0.0 2.2 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain Pyr_redox_2 PF07992.14 KIY63390.1 - 3.8e-29 101.8 0.0 5.2e-29 101.4 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIY63390.1 - 3.2e-10 40.4 0.1 5.9e-10 39.6 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KIY63390.1 - 0.00082 18.5 0.1 0.11 11.5 0.0 2.7 3 0 0 3 3 3 2 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KIY63390.1 - 0.0074 15.6 0.0 0.0095 15.2 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KIY63390.1 - 0.086 12.8 0.4 17 5.3 0.0 2.8 2 1 1 3 3 3 0 FAD-NAD(P)-binding K_oxygenase PF13434.6 KIY63390.1 - 0.1 11.8 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) F-box-like PF12937.7 KIY63391.1 - 1.9e-09 37.3 0.3 3.8e-09 36.3 0.3 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY63391.1 - 0.036 14.0 0.4 0.12 12.3 0.4 1.9 1 1 0 1 1 1 0 F-box domain TPR_1 PF00515.28 KIY63392.1 - 9.1e-09 34.8 1.4 0.045 13.6 0.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KIY63392.1 - 1e-07 31.5 2.1 0.47 10.7 0.2 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat UBA PF00627.31 KIY63392.1 - 0.00019 21.3 1.7 0.0012 18.7 0.0 2.9 4 0 0 4 4 4 1 UBA/TS-N domain TPR_12 PF13424.6 KIY63392.1 - 0.00065 19.9 0.2 0.013 15.7 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat DnaJ PF00226.31 KIY63392.1 - 0.0095 16.0 0.0 0.021 14.9 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain TPR_14 PF13428.6 KIY63392.1 - 3.2 8.8 4.8 19 6.4 0.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat 4HBT PF03061.22 KIY63393.1 - 8.6e-08 32.4 0.0 1.2e-07 31.9 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily Zn_clus PF00172.18 KIY63394.1 - 1.1e-07 31.8 9.9 1.7e-07 31.2 9.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KIY63394.1 - 0.03 13.4 0.0 0.048 12.7 0.0 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain Peptidase_C97 PF05903.14 KIY63395.1 - 4.2e-40 137.1 0.0 6.6e-40 136.4 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain PUL PF08324.11 KIY63395.1 - 5.2e-35 121.0 2.7 7.5e-35 120.5 2.7 1.2 1 0 0 1 1 1 1 PUL domain Thioredoxin PF00085.20 KIY63395.1 - 2.1e-14 53.4 0.0 4.4e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KIY63395.1 - 0.00025 21.5 0.0 0.00062 20.2 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like domain FA_desaturase PF00487.24 KIY63396.1 - 4.9e-27 95.4 23.7 8e-27 94.7 23.7 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 KIY63396.1 - 1.3e-09 38.0 0.0 3.9e-09 36.5 0.0 1.8 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain DUF3821 PF12863.7 KIY63396.1 - 0.063 13.2 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3821) IMS PF00817.20 KIY63397.1 - 1.5e-41 141.9 0.1 4.5e-41 140.3 0.0 1.8 2 0 0 2 2 2 1 impB/mucB/samB family REV1_C PF16727.5 KIY63397.1 - 1e-20 73.9 0.9 2.5e-20 72.6 0.9 1.7 1 0 0 1 1 1 1 DNA repair protein REV1 C-terminal domain IMS_C PF11799.8 KIY63397.1 - 2.5e-15 57.2 0.0 1.3e-14 54.9 0.0 2.2 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain BRCT_2 PF16589.5 KIY63397.1 - 6.8e-09 36.0 0.0 1.4e-08 35.0 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 KIY63397.1 - 9.7e-07 29.0 0.1 2.9e-06 27.5 0.0 1.8 2 0 0 2 2 2 1 DNA ligase 3 BRCT domain BRCT PF00533.26 KIY63397.1 - 0.0099 16.2 0.0 0.021 15.2 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain IMS_HHH PF11798.8 KIY63397.1 - 0.017 15.4 0.0 0.058 13.7 0.0 2.0 1 0 0 1 1 1 0 IMS family HHH motif PTCB-BRCT PF12738.7 KIY63397.1 - 0.061 13.3 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 twin BRCT domain DAO PF01266.24 KIY63399.1 - 4.9e-60 204.0 5.5 7.8e-60 203.3 5.5 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIY63399.1 - 8.3e-07 28.5 0.0 0.023 13.9 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KIY63399.1 - 1.5e-06 27.5 1.1 7e-05 22.1 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain GMC_oxred_N PF00732.19 KIY63399.1 - 5e-06 26.1 0.1 0.00055 19.4 0.0 2.2 2 0 0 2 2 2 1 GMC oxidoreductase Pyr_redox PF00070.27 KIY63399.1 - 3.4e-05 24.3 0.1 0.46 11.1 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIY63399.1 - 0.00027 21.1 0.1 0.00073 19.7 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KIY63399.1 - 0.00058 19.2 0.1 0.0014 17.9 0.1 1.6 1 0 0 1 1 1 1 Thi4 family Mqo PF06039.15 KIY63399.1 - 0.0015 17.1 0.0 1.1 7.8 0.0 2.1 2 0 0 2 2 2 2 Malate:quinone oxidoreductase (Mqo) Trp_halogenase PF04820.14 KIY63399.1 - 0.0037 16.2 0.5 0.012 14.5 0.5 1.7 1 1 0 1 1 1 1 Tryptophan halogenase FAD_oxidored PF12831.7 KIY63399.1 - 0.014 14.7 0.2 0.059 12.7 0.0 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KIY63399.1 - 0.015 14.5 0.0 0.84 8.8 0.0 2.4 2 0 0 2 2 2 0 FAD binding domain ApbA PF02558.16 KIY63399.1 - 0.019 14.6 0.4 0.49 10.0 0.2 2.3 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Sacchrp_dh_NADP PF03435.18 KIY63399.1 - 0.083 13.2 5.9 0.17 12.1 0.2 3.0 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain zf-C2H2 PF00096.26 KIY63399.1 - 0.25 11.9 2.6 0.8 10.3 1.7 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type MCRA PF06100.11 KIY63399.1 - 0.35 9.6 1.9 0.24 10.1 0.2 1.5 2 0 0 2 2 2 0 MCRA family NAD_binding_9 PF13454.6 KIY63399.1 - 0.51 10.3 3.2 1.4 8.9 0.1 2.6 3 0 0 3 3 3 0 FAD-NAD(P)-binding DUF4686 PF15742.5 KIY63399.1 - 0.6 9.2 4.5 0.88 8.6 4.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4686) zf-C2H2_4 PF13894.6 KIY63399.1 - 0.75 10.8 2.6 2.1 9.4 1.6 2.4 2 0 0 2 2 1 0 C2H2-type zinc finger PRKG1_interact PF15898.5 KIY63399.1 - 1 10.3 3.4 27 5.7 0.5 2.6 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain Chromo PF00385.24 KIY63402.1 - 0.14 12.1 0.0 0.33 10.9 0.0 1.7 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain PIP5K PF01504.18 KIY63404.1 - 0.047 12.9 0.8 0.092 12.0 0.8 1.5 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase AAA_assoc_2 PF16193.5 KIY63404.1 - 0.061 13.7 0.0 0.15 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA C-terminal domain NAM-associated PF14303.6 KIY63404.1 - 0.57 10.9 0.0 0.57 10.9 0.0 3.6 3 1 0 4 4 4 0 No apical meristem-associated C-terminal domain DUF5368 PF17336.2 KIY63410.1 - 0.12 12.5 2.1 0.34 11.1 2.1 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5368) TM231 PF10149.9 KIY63410.1 - 0.17 11.2 0.0 0.73 9.1 0.0 1.9 2 0 0 2 2 2 0 Transmembrane protein 231 RseC_MucC PF04246.12 KIY63410.1 - 0.98 9.4 3.8 2.6 8.0 3.8 1.6 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC Glyco_hydro_3_C PF01915.22 KIY63411.1 - 4.2e-52 177.1 0.0 7.9e-52 176.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KIY63411.1 - 3.6e-51 174.4 0.0 4.7e-51 174.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KIY63411.1 - 1.9e-20 72.8 0.4 1.2e-19 70.1 1.0 2.1 2 0 0 2 2 2 1 Fibronectin type III-like domain DUF11 PF01345.18 KIY63411.1 - 0.14 12.5 3.2 0.43 10.9 3.2 1.9 1 0 0 1 1 1 0 Domain of unknown function DUF11 Isochorismatase PF00857.20 KIY63412.1 - 5.5e-20 72.3 0.0 1.8e-19 70.6 0.0 1.7 1 1 0 1 1 1 1 Isochorismatase family Glyco_hydro_61 PF03443.14 KIY63413.1 - 1.8e-48 165.2 0.0 2.9e-48 164.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 SOG2 PF10428.9 KIY63413.1 - 1.5 7.9 22.4 2.1 7.4 22.4 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Glyco_hydro_61 PF03443.14 KIY63414.1 - 9.5e-51 172.6 0.0 1.2e-50 172.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 EPL1 PF10513.9 KIY63417.1 - 6.2e-14 52.7 0.5 2.4e-13 50.8 0.0 2.2 2 0 0 2 2 2 1 Enhancer of polycomb-like PSP PF04046.16 KIY63417.1 - 0.019 14.9 0.3 0.074 12.9 0.3 2.0 1 0 0 1 1 1 0 PSP PCRF PF03462.18 KIY63418.1 - 1.8e-51 174.8 0.1 1.4e-50 171.9 0.0 2.0 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 KIY63418.1 - 5e-33 113.5 6.1 8.9e-33 112.7 6.1 1.4 1 0 0 1 1 1 1 RF-1 domain PSY3 PF16836.5 KIY63418.1 - 0.00054 19.6 0.1 0.021 14.3 0.1 2.4 3 0 0 3 3 3 1 Shu complex component Psy3, DNA-binding description DUF1275 PF06912.11 KIY63419.1 - 3.4e-19 69.5 10.1 4e-19 69.3 10.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DUF4131 PF13567.6 KIY63419.1 - 0.012 15.3 2.3 0.53 9.9 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Acyl_transf_3 PF01757.22 KIY63419.1 - 0.14 11.2 5.8 0.016 14.3 1.8 1.4 2 0 0 2 2 2 0 Acyltransferase family PrgI PF12666.7 KIY63419.1 - 0.49 11.1 2.7 4.8 7.9 0.1 2.3 2 0 0 2 2 2 0 PrgI family protein LRR_4 PF12799.7 KIY63420.1 - 0.00069 20.0 2.0 1.4 9.5 0.0 4.9 5 1 0 5 5 5 2 Leucine Rich repeats (2 copies) DAHP_synth_2 PF01474.16 KIY63421.1 - 2.4e-198 659.0 0.0 2.8e-198 658.9 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family SPX PF03105.19 KIY63422.1 - 1.1e-37 130.8 2.9 3.4e-37 129.3 2.9 1.8 1 1 0 1 1 1 1 SPX domain zf-C3HC4 PF00097.25 KIY63422.1 - 1.3e-07 31.4 7.4 2.3e-07 30.6 7.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KIY63422.1 - 1.6e-07 31.1 6.2 2.7e-07 30.3 6.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KIY63422.1 - 5.8e-07 29.6 6.9 1e-06 28.8 6.9 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KIY63422.1 - 4.6e-06 26.9 7.6 7.9e-06 26.1 7.6 1.4 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 KIY63422.1 - 8.6e-06 25.5 7.1 8.6e-06 25.5 7.1 1.7 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KIY63422.1 - 9.7e-05 22.1 8.4 0.00017 21.3 8.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KIY63422.1 - 0.00012 22.0 5.8 0.00023 21.1 5.8 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.6 KIY63422.1 - 0.00013 21.6 2.4 0.00032 20.4 2.4 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.6 KIY63422.1 - 0.00022 21.1 7.7 0.00042 20.2 7.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 KIY63422.1 - 0.0032 17.7 3.5 0.0065 16.7 3.5 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_6 PF14835.6 KIY63422.1 - 0.012 15.4 3.3 0.023 14.6 3.3 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 KIY63422.1 - 0.038 14.1 3.5 0.068 13.3 3.5 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-ANAPC11 PF12861.7 KIY63422.1 - 0.044 13.8 1.5 0.08 13.0 1.5 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger YabA PF06156.13 KIY63422.1 - 2.8 8.6 4.5 1.2 9.8 0.1 2.6 3 0 0 3 3 2 0 Initiation control protein YabA AA_permease_2 PF13520.6 KIY63423.1 - 4.2e-78 263.1 31.2 5.2e-78 262.8 31.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KIY63423.1 - 5.5e-18 64.8 27.8 9.1e-18 64.1 27.8 1.3 1 1 0 1 1 1 1 Amino acid permease HDOD PF08668.12 KIY63423.1 - 0.14 11.7 0.2 0.31 10.5 0.2 1.5 1 0 0 1 1 1 0 HDOD domain DUF2157 PF09925.9 KIY63423.1 - 2.3 8.0 11.0 0.17 11.7 0.6 3.4 3 1 0 3 3 3 0 Predicted membrane protein (DUF2157) COG6 PF06419.11 KIY63425.1 - 1.8e-140 469.2 0.2 2.2e-140 468.9 0.2 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 ZapB PF06005.12 KIY63425.1 - 0.57 10.7 5.5 1.4 9.4 0.5 2.8 2 0 0 2 2 2 0 Cell division protein ZapB Abhydrolase_1 PF00561.20 KIY63426.1 - 1.2e-11 44.8 0.3 1.1e-07 31.8 0.3 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIY63426.1 - 7.6e-07 30.0 1.2 2.4e-05 25.1 2.4 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 KIY63426.1 - 7.3e-05 22.5 0.0 0.00012 21.8 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_2 PF02230.16 KIY63426.1 - 0.0014 18.5 0.0 0.0041 16.9 0.0 1.7 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 KIY63426.1 - 0.013 14.8 0.0 0.066 12.5 0.0 1.8 1 1 0 2 2 2 0 Serine aminopeptidase, S33 ABM PF03992.16 KIY63427.1 - 4.1e-05 23.6 0.6 0.00013 22.0 0.3 1.9 2 0 0 2 2 2 1 Antibiotic biosynthesis monooxygenase NIPSNAP PF07978.13 KIY63427.1 - 0.00016 21.9 0.1 0.00025 21.2 0.1 1.3 1 0 0 1 1 1 1 NIPSNAP SOR PF07682.11 KIY63427.1 - 0.025 13.5 0.2 2.5 6.9 0.0 2.1 1 1 1 2 2 2 0 Sulphur oxygenase reductase Peptidase_M16_M PF16187.5 KIY63428.1 - 5.2e-95 317.9 0.7 3e-94 315.4 1.0 1.9 2 0 0 2 2 2 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 KIY63428.1 - 2e-39 134.9 0.0 8.5e-39 132.9 0.1 2.0 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KIY63428.1 - 1.1e-19 71.1 0.0 4.1e-08 33.4 0.0 3.2 3 0 0 3 3 3 2 Peptidase M16 inactive domain GTP_CH_N PF12471.8 KIY63433.1 - 2.3e-79 265.7 0.0 3.3e-79 265.2 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 KIY63433.1 - 1.1e-14 54.4 0.0 1.6e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II Amidohydro_2 PF04909.14 KIY63435.1 - 1.5e-08 34.8 0.1 2.3e-08 34.2 0.1 1.3 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.20 KIY63435.1 - 9e-07 28.5 0.1 2.1e-06 27.3 0.1 1.5 1 1 0 1 1 1 1 Amidohydrolase family DeoC PF01791.9 KIY63438.1 - 3.2e-15 56.4 6.1 4.1e-15 56.1 6.1 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase SKN1 PF03935.15 KIY63440.1 - 7.2e-190 631.6 8.0 8.4e-190 631.4 8.0 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) BTB PF00651.31 KIY63442.1 - 0.077 13.2 0.0 6.3 7.1 0.0 2.4 2 0 0 2 2 2 0 BTB/POZ domain Methyltransf_25 PF13649.6 KIY63443.1 - 1.5e-13 51.3 0.0 2.3e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIY63443.1 - 5e-13 49.5 0.0 6.9e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIY63443.1 - 5.8e-13 49.0 0.0 7e-13 48.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIY63443.1 - 1.5e-11 44.9 0.0 1.9e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIY63443.1 - 3e-10 40.1 0.0 3.6e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIY63443.1 - 0.00052 19.4 0.0 0.0027 17.1 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KIY63443.1 - 0.0093 15.5 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 KIY63443.1 - 0.014 15.4 0.0 0.015 15.3 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain NodS PF05401.11 KIY63443.1 - 0.03 13.9 0.0 0.045 13.4 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) TPMT PF05724.11 KIY63443.1 - 0.23 11.1 0.0 0.87 9.2 0.0 1.9 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Macoilin PF09726.9 KIY63444.1 - 6.3 5.2 13.6 11 4.4 13.6 1.3 1 0 0 1 1 1 0 Macoilin family DUF2953 PF11167.8 KIY63447.1 - 0.0045 17.0 0.6 0.0089 16.1 0.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2953) FAA_hydrolase_N PF09298.11 KIY63447.1 - 0.41 10.9 2.4 0.57 10.4 1.1 1.9 1 1 0 1 1 1 0 Fumarylacetoacetase N-terminal CPSF73-100_C PF11718.8 KIY63448.1 - 2.3e-55 187.5 0.0 4.2e-55 186.7 0.0 1.4 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 KIY63448.1 - 4.2e-29 101.1 0.0 1.3e-28 99.4 0.0 1.9 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B PF00753.27 KIY63448.1 - 2.4e-17 63.6 1.6 1.1e-16 61.5 1.3 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 KIY63448.1 - 1.4e-16 60.5 0.0 3.4e-16 59.3 0.0 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 KIY63448.1 - 4.8e-16 58.4 0.1 1.1e-15 57.3 0.1 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_3 PF13483.6 KIY63448.1 - 1.3e-07 31.6 0.1 2.4e-06 27.5 0.0 2.7 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 KIY63448.1 - 6.9e-07 29.0 2.3 2.3e-06 27.3 0.4 2.5 3 0 0 3 3 3 1 Beta-lactamase superfamily domain Josephin PF02099.17 KIY63450.1 - 2.2e-43 148.2 0.0 4.4e-43 147.2 0.0 1.5 1 0 0 1 1 1 1 Josephin N6_Mtase PF02384.16 KIY63450.1 - 0.14 11.4 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 N-6 DNA Methylase ALG3 PF05208.13 KIY63451.1 - 3.2e-125 418.3 12.2 3.8e-125 418.0 12.2 1.0 1 0 0 1 1 1 1 ALG3 protein KxDL PF10241.9 KIY63452.1 - 3.7 7.9 11.1 0.23 11.7 1.1 2.7 1 1 2 3 3 3 0 Uncharacterized conserved protein DUF4407 PF14362.6 KIY63452.1 - 5.2 6.3 13.3 8.1 5.7 13.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AXE1 PF05448.12 KIY63453.1 - 0.077 11.7 0.0 0.092 11.4 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) CorA PF01544.18 KIY63454.1 - 0.017 14.5 4.3 0.023 14.0 4.3 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Golgin_A5 PF09787.9 KIY63454.1 - 0.055 12.9 8.7 0.08 12.4 8.7 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 zf-ZPR1 PF03367.13 KIY63454.1 - 0.15 11.9 3.0 0.25 11.2 3.0 1.3 1 0 0 1 1 1 0 ZPR1 zinc-finger domain DUF1640 PF07798.11 KIY63454.1 - 0.4 10.7 16.9 2.1 8.4 16.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) Lebercilin PF15619.6 KIY63454.1 - 0.52 9.9 19.2 1.1 8.9 18.4 1.8 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease AAA_13 PF13166.6 KIY63454.1 - 4.6 5.8 14.5 6.5 5.3 14.5 1.1 1 0 0 1 1 1 0 AAA domain DUF4094 PF13334.6 KIY63454.1 - 4.7 7.7 8.4 4 7.9 1.1 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) DUF4472 PF14739.6 KIY63454.1 - 5 7.9 14.0 10 6.9 5.2 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) SidE PF12252.8 KIY63454.1 - 6 4.3 13.2 1.1 6.7 8.2 1.9 1 1 1 2 2 2 0 Dot/Icm substrate protein Cellulase PF00150.18 KIY63455.1 - 4.6e-06 26.3 0.0 8.8e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Viral_Beta_CD PF04530.12 KIY63455.1 - 0.077 13.3 0.0 0.22 11.8 0.0 1.7 1 0 0 1 1 1 0 Viral Beta C/D like family Glyco_hydro_43 PF04616.14 KIY63458.1 - 2.7e-42 145.1 9.1 3e-42 144.9 9.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 DUF676 PF05057.14 KIY63459.1 - 2.7e-37 128.4 0.0 4e-37 127.9 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.25 KIY63459.1 - 0.012 15.5 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) PGAP1 PF07819.13 KIY63459.1 - 0.022 14.5 0.0 0.033 13.9 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Palm_thioest PF02089.15 KIY63459.1 - 0.083 12.7 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase DUF1843 PF08898.10 KIY63460.1 - 0.24 12.0 0.5 0.39 11.3 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1843) PI3_PI4_kinase PF00454.27 KIY63461.1 - 1.5e-51 175.6 0.0 3e-51 174.6 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.8 KIY63461.1 - 6.8e-16 58.7 0.3 2.1e-15 57.1 0.3 2.0 1 0 0 1 1 1 1 Telomere-length maintenance and DNA damage repair FATC PF02260.20 KIY63461.1 - 1.8e-07 30.9 0.0 4e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 FATC domain VirB8 PF04335.13 KIY63461.1 - 0.13 12.1 0.0 0.3 10.9 0.0 1.6 1 0 0 1 1 1 0 VirB8 protein Sugar_tr PF00083.24 KIY63462.1 - 7.7e-86 288.7 19.8 9.2e-86 288.5 19.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY63462.1 - 6.9e-10 38.4 44.4 2.3e-08 33.4 18.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_28 PF00295.17 KIY63463.1 - 3.9e-38 131.3 0.6 6.6e-38 130.6 0.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.6 KIY63463.1 - 2.4 8.0 15.9 1.1 9.2 11.5 2.2 1 1 1 2 2 2 0 Right handed beta helix region An_peroxidase PF03098.15 KIY63464.1 - 4.8e-37 127.7 0.0 1.4e-27 96.6 0.0 3.2 1 1 1 2 2 2 2 Animal haem peroxidase Pkinase PF00069.25 KIY63465.1 - 4.3e-73 245.9 0.0 5.8e-73 245.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY63465.1 - 3e-48 164.4 0.0 4.7e-48 163.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 KIY63465.1 - 2.8e-23 82.0 0.1 6.1e-23 80.9 0.1 1.6 1 0 0 1 1 1 1 P21-Rho-binding domain Pkinase_fungal PF17667.1 KIY63465.1 - 0.00015 20.7 0.2 0.0003 19.7 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 KIY63465.1 - 0.00026 20.4 0.0 0.00042 19.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KIY63465.1 - 0.0089 15.4 0.1 0.021 14.2 0.1 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIY63465.1 - 0.041 13.8 0.4 0.3 11.0 0.4 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Mcm10 PF09332.11 KIY63465.1 - 0.15 11.5 3.6 0.29 10.5 3.6 1.4 1 0 0 1 1 1 0 Mcm10 replication factor DSHCT PF08148.12 KIY63465.1 - 0.16 11.6 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 DSHCT (NUC185) domain AAA PF00004.29 KIY63466.1 - 4.9e-14 52.9 0.0 6e-13 49.4 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KIY63466.1 - 0.0089 16.3 0.4 0.5 10.6 0.0 2.6 1 1 1 2 2 2 1 AAA domain AAA_30 PF13604.6 KIY63466.1 - 0.044 13.5 0.1 0.14 11.8 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KIY63466.1 - 0.055 13.9 0.2 0.21 12.0 0.2 2.2 1 1 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 KIY63466.1 - 0.13 12.3 0.0 0.4 10.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF5427 PF10310.9 KIY63467.1 - 0.28 10.1 1.3 0.43 9.5 1.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Ribosomal_S25 PF03297.15 KIY63468.1 - 2.2e-38 130.5 1.4 2.9e-38 130.1 1.4 1.1 1 0 0 1 1 1 1 S25 ribosomal protein HTH_24 PF13412.6 KIY63468.1 - 0.011 15.2 0.1 0.025 14.1 0.1 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MarR PF01047.22 KIY63468.1 - 0.02 14.8 0.1 0.033 14.1 0.1 1.4 1 0 0 1 1 1 0 MarR family AIPR PF10592.9 KIY63468.1 - 0.091 12.4 0.0 0.095 12.3 0.0 1.1 1 0 0 1 1 1 0 AIPR protein MerR PF00376.23 KIY63468.1 - 0.092 12.5 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 MerR family regulatory protein PRKCSH-like PF12999.7 KIY63469.1 - 1.9e-48 164.6 0.6 6.9e-48 162.7 0.1 2.1 2 0 0 2 2 2 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 KIY63469.1 - 2.8e-26 92.1 1.1 3.6e-26 91.7 0.2 1.6 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 KIY63469.1 - 1.1e-09 39.2 4.9 1.3e-09 39.0 2.8 2.2 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein FUSC PF04632.12 KIY63469.1 - 0.58 8.6 3.2 0.82 8.1 3.2 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family PEP-utilisers_N PF05524.13 KIY63469.1 - 0.95 9.6 11.5 0.27 11.4 3.0 3.0 2 1 1 3 3 3 0 PEP-utilising enzyme, N-terminal Ldl_recept_a PF00057.18 KIY63469.1 - 3 8.1 17.2 0.33 11.2 5.2 2.6 1 1 1 2 2 2 0 Low-density lipoprotein receptor domain class A Kri1 PF05178.12 KIY63469.1 - 5.5 7.6 10.2 28 5.4 3.4 3.4 1 1 0 2 2 2 0 KRI1-like family SlyX PF04102.12 KIY63469.1 - 6.8 7.4 6.9 23 5.7 0.6 2.8 1 1 1 2 2 2 0 SlyX SH3_1 PF00018.28 KIY63470.1 - 2.8e-12 46.1 0.2 4e-12 45.5 0.2 1.2 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KIY63470.1 - 3.5e-12 46.0 0.2 5.5e-12 45.3 0.2 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KIY63470.1 - 1.2e-09 37.7 0.0 1.8e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SOG2 PF10428.9 KIY63470.1 - 0.39 9.9 4.6 0.43 9.7 4.6 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DAO PF01266.24 KIY63472.1 - 1.5e-59 202.4 0.0 1.7e-59 202.2 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIY63472.1 - 3e-05 23.4 0.0 0.00096 18.5 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIY63472.1 - 3.4e-05 24.0 0.0 6.9e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Mqo PF06039.15 KIY63472.1 - 0.00022 19.9 0.0 0.012 14.2 0.0 2.3 3 0 0 3 3 3 1 Malate:quinone oxidoreductase (Mqo) Pyr_redox PF00070.27 KIY63472.1 - 0.00075 20.0 0.0 0.0025 18.4 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KIY63472.1 - 0.00094 18.5 0.0 0.0014 18.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KIY63472.1 - 0.038 13.3 0.0 1.7 7.9 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.17 KIY63472.1 - 0.051 12.8 0.0 0.12 11.6 0.0 1.5 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.24 KIY63472.1 - 0.12 11.5 0.0 0.24 10.4 0.0 1.5 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.12 KIY63472.1 - 0.14 11.2 0.0 2.1 7.3 0.0 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein Thr_synth_N PF14821.6 KIY63473.1 - 0.022 15.0 0.1 0.047 13.9 0.1 1.6 1 0 0 1 1 1 0 Threonine synthase N terminus COMPASS-Shg1 PF05205.12 KIY63474.1 - 1.1e-11 45.3 0.2 1.3e-11 45.1 0.2 1.1 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component shg1 RNase_J_C PF17770.1 KIY63474.1 - 0.081 14.0 0.2 0.13 13.4 0.2 1.3 1 0 0 1 1 1 0 Ribonuclease J C-terminal domain p450 PF00067.22 KIY63475.1 - 7.6e-63 212.8 0.0 9.6e-63 212.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Not3 PF04065.15 KIY63476.1 - 2e-89 299.0 23.2 3.7e-89 298.1 23.2 1.5 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 KIY63476.1 - 1.3e-42 145.0 10.2 5.4e-42 143.0 10.2 2.1 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Syntaxin_2 PF14523.6 KIY63476.1 - 0.0069 16.7 3.5 0.0069 16.7 3.5 1.9 2 0 0 2 2 2 1 Syntaxin-like protein NAD_binding_5 PF07994.12 KIY63476.1 - 0.16 11.3 1.8 0.28 10.5 1.8 1.4 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase Cep57_MT_bd PF06657.13 KIY63476.1 - 0.28 11.7 8.5 0.63 10.5 1.5 2.8 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Swi5 PF07061.11 KIY63476.1 - 1.2 9.3 7.2 9.3 6.4 0.4 2.9 2 0 0 2 2 2 0 Swi5 DUF4140 PF13600.6 KIY63476.1 - 2.3 8.7 6.3 3.6 8.1 0.6 2.9 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) PRKG1_interact PF15898.5 KIY63476.1 - 4.5 8.2 16.6 8.3 7.4 4.3 2.9 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain HR1 PF02185.16 KIY63476.1 - 7.4 6.8 11.3 0.34 11.0 3.3 2.5 2 0 0 2 2 2 0 Hr1 repeat IFT20 PF14931.6 KIY63476.1 - 8.4 6.6 18.7 0.68 10.1 7.9 2.5 1 1 1 2 2 2 0 Intraflagellar transport complex B, subunit 20 Ribosomal_L12 PF00542.19 KIY63477.1 - 5.3e-21 74.7 2.5 1.6e-19 70.0 2.1 2.2 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 KIY63477.1 - 2.8e-13 49.3 1.8 2.8e-13 49.3 1.8 3.4 3 1 0 3 3 3 1 Ribosomal protein L7/L12 dimerisation domain Flavokinase PF01687.17 KIY63478.1 - 1.5e-30 105.7 0.0 2.1e-30 105.3 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase Aconitase PF00330.20 KIY63479.1 - 1e-161 539.0 0.0 1.2e-161 538.8 0.0 1.0 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KIY63479.1 - 1.2e-39 135.6 0.0 2.1e-39 134.8 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain DSBA PF01323.20 KIY63480.1 - 0.11 12.3 0.1 0.19 11.5 0.1 1.5 1 1 1 2 2 2 0 DSBA-like thioredoxin domain ADH_N PF08240.12 KIY63481.1 - 5.4e-27 93.8 0.4 1e-26 92.9 0.4 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_assoc PF13823.6 KIY63481.1 - 0.0012 18.7 0.1 0.0012 18.7 0.1 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated ADH_zinc_N_2 PF13602.6 KIY63481.1 - 0.025 15.6 0.0 0.16 13.0 0.0 2.2 2 1 0 2 2 2 0 Zinc-binding dehydrogenase Pyr_redox_2 PF07992.14 KIY63481.1 - 0.043 13.0 0.0 0.074 12.3 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KIY63481.1 - 0.052 12.3 0.0 0.074 11.7 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein PP2C PF00481.21 KIY63482.1 - 1e-12 48.3 0.0 2.3e-12 47.1 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C PAC4 PF16093.5 KIY63482.1 - 0.13 12.4 0.4 2.2 8.5 0.2 2.4 1 1 1 2 2 2 0 Proteasome assembly chaperone 4 ADH_zinc_N PF00107.26 KIY63485.1 - 2.6e-29 101.8 0.7 4.1e-29 101.2 0.7 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KIY63485.1 - 7.1e-19 69.2 0.1 1.2e-18 68.5 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIY63485.1 - 1.4e-08 34.5 0.1 4e-08 33.1 0.1 1.9 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 KIY63485.1 - 0.042 13.1 0.4 0.071 12.4 0.4 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain F-box-like PF12937.7 KIY63486.1 - 1.4e-05 24.9 0.1 1.4e-05 24.9 0.1 2.2 3 0 0 3 3 3 1 F-box-like zf-CCHH PF10283.9 KIY63486.1 - 0.0041 17.1 1.1 0.0071 16.3 1.1 1.4 1 0 0 1 1 1 1 PBZ domain F-box PF00646.33 KIY63486.1 - 0.093 12.6 0.0 0.24 11.3 0.0 1.8 1 0 0 1 1 1 0 F-box domain GATA PF00320.27 KIY63486.1 - 0.62 9.7 4.7 1.1 8.9 2.2 2.3 2 0 0 2 2 2 0 GATA zinc finger F-box-like PF12937.7 KIY63487.1 - 7e-06 25.8 0.1 7e-06 25.8 0.1 2.6 3 1 0 3 3 3 1 F-box-like F-box PF00646.33 KIY63487.1 - 0.0008 19.2 0.1 0.0045 16.8 0.0 2.4 2 0 0 2 2 2 1 F-box domain F-box_5 PF18511.1 KIY63487.1 - 0.017 14.7 0.1 0.061 12.9 0.0 2.1 2 0 0 2 2 2 0 F-box F-box-like PF12937.7 KIY63488.1 - 8.8e-05 22.3 0.2 0.00031 20.6 0.0 2.1 2 0 0 2 2 2 1 F-box-like zf-CCHH PF10283.9 KIY63488.1 - 0.11 12.5 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 PBZ domain Dynactin_p62 PF05502.13 KIY63493.1 - 3e-70 237.3 10.0 6.9e-42 143.8 6.6 2.1 1 1 1 2 2 2 2 Dynactin p62 family TatD_DNase PF01026.21 KIY63494.1 - 7.3e-46 156.6 0.0 8.7e-46 156.4 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.14 KIY63494.1 - 0.00028 20.8 0.1 0.0056 16.5 0.1 2.8 1 1 0 1 1 1 1 Amidohydrolase TPR_2 PF07719.17 KIY63496.1 - 0.14 12.3 1.0 1.1 9.6 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Ufd2P_core PF10408.9 KIY63497.1 - 2.2e-210 700.5 0.0 2.6e-210 700.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 KIY63497.1 - 6.7e-29 99.9 0.5 2.4e-28 98.1 0.5 2.0 1 0 0 1 1 1 1 U-box domain zf-MYND PF01753.18 KIY63498.1 - 3e-07 30.4 8.2 7e-07 29.2 8.2 1.6 1 0 0 1 1 1 1 MYND finger DUF2785 PF10978.8 KIY63498.1 - 0.11 12.3 0.4 0.19 11.5 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2785) PilW PF16074.5 KIY63499.1 - 0.12 12.4 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Type IV Pilus-assembly protein W Transposase_21 PF02992.14 KIY63500.1 - 3.5e-07 29.7 0.0 1.1e-06 28.0 0.0 1.8 2 0 0 2 2 2 1 Transposase family tnp2 AP1AR PF15745.5 KIY63500.1 - 0.023 14.4 3.6 0.038 13.6 3.6 1.3 1 0 0 1 1 1 0 AP-1 complex-associated regulatory protein MFS_1 PF07690.16 KIY63502.1 - 5.8e-36 124.2 35.6 5.8e-36 124.2 35.6 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KIY63502.1 - 0.00042 18.9 4.8 0.00049 18.7 1.1 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) DSPc PF00782.20 KIY63503.1 - 8.9e-07 28.8 0.0 1.1e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain CDKN3 PF05706.12 KIY63503.1 - 1.4e-06 28.1 0.0 1.8e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.6 KIY63503.1 - 0.00019 21.6 0.0 0.00031 20.9 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 KIY63503.1 - 0.0003 20.8 0.0 0.00051 20.1 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 KIY63503.1 - 0.0011 18.5 0.0 0.0017 18.0 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Met_synt_B12 PF02965.17 KIY63503.1 - 0.08 12.4 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Vitamin B12 dependent methionine synthase, activation domain Histone PF00125.24 KIY63504.1 - 4.8e-11 43.1 0.3 4.8e-11 43.1 0.3 1.9 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 KIY63504.1 - 0.0078 15.9 0.7 0.015 15.1 0.0 1.9 2 0 0 2 2 2 1 C-terminus of histone H2A Peptidase_M50B PF13398.6 KIY63505.1 - 1.4e-43 148.9 14.7 1.7e-43 148.6 14.7 1.1 1 0 0 1 1 1 1 Peptidase M50B-like AmiS_UreI PF02293.15 KIY63505.1 - 8.9e-05 22.6 9.6 0.00018 21.6 9.6 1.5 1 0 0 1 1 1 1 AmiS/UreI family transporter AMP-binding PF00501.28 KIY63506.1 - 5e-31 107.7 0.8 9.8e-31 106.8 0.0 1.9 3 0 0 3 3 3 1 AMP-binding enzyme NAD_binding_4 PF07993.12 KIY63506.1 - 7.7e-31 107.2 0.0 1.2e-30 106.5 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 KIY63506.1 - 1e-09 38.2 0.0 2.7e-09 36.8 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KIY63506.1 - 7.4e-09 35.8 0.0 1.9e-08 34.6 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site KR PF08659.10 KIY63506.1 - 0.00074 19.5 0.0 0.0017 18.3 0.0 1.7 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KIY63506.1 - 0.033 13.3 0.0 0.055 12.6 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.24 KIY63506.1 - 0.035 14.5 0.4 0.3 11.6 0.1 2.7 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain IBR PF01485.21 KIY63508.1 - 1.8e-11 44.1 14.5 2e-07 31.1 0.8 5.4 5 1 1 6 6 6 2 IBR domain, a half RING-finger domain zf-CCCH PF00642.24 KIY63508.1 - 4.9e-08 32.7 21.0 9.6e-05 22.2 0.2 4.6 4 0 0 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KIY63508.1 - 2.3e-05 25.0 11.6 0.22 12.2 0.4 4.1 3 1 1 4 4 4 3 Torus domain zf-C3HC4_4 PF15227.6 KIY63508.1 - 0.00046 20.3 6.2 0.00046 20.3 6.2 3.9 4 0 0 4 4 4 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 KIY63508.1 - 0.0005 20.0 7.5 0.0005 20.0 7.5 3.6 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KIY63508.1 - 0.00053 19.8 4.3 0.00053 19.8 4.3 3.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIY63508.1 - 0.00084 19.2 4.0 0.00084 19.2 4.0 3.6 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.22 KIY63508.1 - 0.0016 18.2 0.0 0.0043 16.8 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2_6 PF13912.6 KIY63508.1 - 0.051 13.6 0.2 0.94 9.6 0.1 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-B_box PF00643.24 KIY63508.1 - 5.7 7.2 14.0 3.6 7.8 0.4 3.0 2 0 0 2 2 2 0 B-box zinc finger 2OG-FeII_Oxy_3 PF13640.6 KIY63509.1 - 3.1e-10 40.8 0.0 5.9e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 KIY63509.1 - 0.1 13.1 0.0 0.27 11.8 0.0 1.7 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily DPM3 PF08285.11 KIY63510.1 - 1.5e-30 105.2 0.6 1.6e-30 105.1 0.6 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Fis1_TPR_C PF14853.6 KIY63511.1 - 1.6e-23 82.5 0.1 2.4e-23 82.0 0.1 1.3 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 KIY63511.1 - 3.8e-16 58.4 0.0 6.6e-16 57.7 0.0 1.4 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.17 KIY63511.1 - 0.0003 20.7 0.3 0.00054 19.9 0.3 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 KIY63511.1 - 0.015 15.1 0.3 0.027 14.3 0.3 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_19 PF14559.6 KIY63511.1 - 0.029 14.9 0.1 0.044 14.3 0.1 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.6 KIY63511.1 - 0.04 14.6 0.0 0.11 13.2 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat RRM_1 PF00076.22 KIY63512.1 - 2.6e-30 104.0 3.1 1.2e-15 57.0 0.0 5.2 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KIY63512.1 - 2e-08 34.0 0.0 0.21 11.5 0.0 3.6 3 0 0 3 3 3 3 Occluded RNA-recognition motif RRM_7 PF16367.5 KIY63512.1 - 6e-06 26.3 0.0 0.002 18.2 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif RRM_9 PF18444.1 KIY63512.1 - 0.055 13.3 0.1 4.1 7.3 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif RRM_1 PF00076.22 KIY63513.1 - 7.2e-10 38.5 0.0 0.00027 20.7 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Type_III_YscG PF09477.10 KIY63513.1 - 0.16 12.1 0.1 0.71 10.0 0.0 1.9 2 0 0 2 2 2 0 Bacterial type II secretion system chaperone protein (type_III_yscG) Ribul_P_3_epim PF00834.19 KIY63514.1 - 7.3e-46 156.1 0.0 2.6e-44 151.0 0.0 2.0 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family OMPdecase PF00215.24 KIY63514.1 - 0.057 13.0 0.0 0.085 12.4 0.0 1.3 1 0 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family Clavanin PF05452.11 KIY63515.1 - 0.14 12.3 0.0 0.29 11.4 0.0 1.5 2 0 0 2 2 2 0 Clavanin Myosin_N PF02736.19 KIY63515.1 - 1.3 8.9 4.3 30 4.5 0.1 2.9 2 1 1 3 3 3 0 Myosin N-terminal SH3-like domain COX6A PF02046.15 KIY63517.1 - 1.7e-27 96.1 0.1 2e-27 95.9 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa RPN2_C PF18004.1 KIY63518.1 - 1.6e-41 141.9 3.9 5.9e-40 136.8 4.5 2.2 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 KIY63518.1 - 9.1e-31 104.7 21.6 3.1e-08 33.6 0.0 8.6 8 0 0 8 8 8 7 Proteasome/cyclosome repeat HEAT_2 PF13646.6 KIY63518.1 - 3.6e-17 62.5 1.0 8.8e-14 51.7 0.0 4.2 4 0 0 4 4 4 1 HEAT repeats HEAT PF02985.22 KIY63518.1 - 0.00026 21.0 0.6 6.6 7.3 0.1 4.1 3 0 0 3 3 3 2 HEAT repeat HEAT_EZ PF13513.6 KIY63518.1 - 0.00092 19.7 2.6 0.49 11.0 0.1 4.6 3 1 1 4 4 4 2 HEAT-like repeat MetRS-N PF09635.10 KIY63518.1 - 0.13 12.8 0.1 0.47 11.0 0.1 1.9 1 0 0 1 1 1 0 MetRS-N binding domain MFS_1 PF07690.16 KIY63519.1 - 9.3e-48 162.9 29.3 2.5e-43 148.4 18.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily CCCAP PF15964.5 KIY63519.1 - 0.23 9.7 0.3 0.33 9.2 0.3 1.1 1 0 0 1 1 1 0 Centrosomal colon cancer autoantigen protein family LapA_dom PF06305.11 KIY63519.1 - 0.86 9.5 0.0 0.86 9.5 0.0 3.7 5 0 0 5 5 5 0 Lipopolysaccharide assembly protein A domain ICE2 PF08426.10 KIY63520.1 - 1.2e-23 83.9 26.1 4.3e-12 45.9 14.8 2.9 2 1 0 2 2 2 2 ICE2 BRCT_2 PF16589.5 KIY63521.1 - 1.5e-17 63.8 0.1 2.2e-11 44.0 0.0 2.6 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KIY63521.1 - 1.2e-06 28.8 0.1 0.00047 20.5 0.0 2.7 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain Glyco_trans_1_4 PF13692.6 KIY63521.1 - 0.11 12.9 0.0 0.25 11.8 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 BRCT_2 PF16589.5 KIY63522.1 - 1.7e-15 57.2 0.0 4.9e-10 39.7 0.0 2.5 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KIY63522.1 - 6.2e-07 29.7 0.1 0.0021 18.4 0.0 2.4 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain DUF3864 PF12980.7 KIY63522.1 - 0.016 15.5 0.1 0.05 13.9 0.1 1.8 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3864) BRCT_2 PF16589.5 KIY63524.1 - 5.5e-18 65.2 0.0 1.8e-10 41.1 0.0 2.7 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KIY63524.1 - 1.1e-05 25.7 0.0 0.0004 20.7 0.0 2.7 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain F-box-like PF12937.7 KIY63525.1 - 0.0017 18.2 0.0 0.0032 17.3 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KIY63525.1 - 0.0089 15.9 0.0 0.017 15.0 0.0 1.5 1 0 0 1 1 1 1 F-box NUC153 PF08159.12 KIY63526.1 - 1.4e-10 40.8 0.7 1.4e-10 40.8 0.7 4.6 4 0 0 4 4 4 3 NUC153 domain UPF0203 PF05254.12 KIY63528.1 - 3.1e-25 88.2 1.6 4.5e-25 87.7 1.6 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) Pet191_N PF10203.9 KIY63528.1 - 0.0098 16.2 0.5 1.3 9.3 0.1 2.2 2 0 0 2 2 2 2 Cytochrome c oxidase assembly protein PET191 COX17 PF05051.13 KIY63528.1 - 0.032 14.6 0.4 5.4 7.5 0.1 2.3 2 0 0 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) NDUFB10 PF10249.9 KIY63528.1 - 0.054 14.0 0.2 0.069 13.6 0.2 1.3 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit 10 CHCH PF06747.13 KIY63528.1 - 0.056 13.6 1.4 0.4 10.9 0.2 2.2 2 0 0 2 2 2 0 CHCH domain COX6B PF02297.17 KIY63528.1 - 0.071 13.4 2.9 1.9 8.8 0.1 2.2 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb Peptidase_S10 PF00450.22 KIY63529.1 - 1.5e-90 304.6 1.6 1.9e-90 304.3 1.6 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Glyco_hydro_18 PF00704.28 KIY63530.1 - 1.9e-23 83.7 5.3 4.8e-23 82.4 5.3 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 DUF1748 PF08520.10 KIY63531.1 - 1.4e-22 79.4 0.0 1.5e-22 79.2 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) FctA PF12892.7 KIY63532.1 - 0.044 14.6 1.6 0.057 14.2 0.3 1.7 1 1 1 2 2 2 0 Spy0128-like isopeptide containing domain SOG2 PF10428.9 KIY63532.1 - 0.3 10.2 19.2 0.35 10.0 19.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Macoilin PF09726.9 KIY63532.1 - 5.2 5.5 14.0 6.4 5.2 14.0 1.2 1 0 0 1 1 1 0 Macoilin family SH3_9 PF14604.6 KIY63533.1 - 4.2e-16 58.5 0.2 6.5e-16 57.9 0.2 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KIY63533.1 - 3.3e-14 52.2 0.6 4.8e-14 51.7 0.6 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KIY63533.1 - 4.8e-14 51.8 0.0 7.3e-14 51.2 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Voldacs PF03517.13 KIY63534.1 - 2.4e-13 50.4 0.8 6.5e-08 32.8 0.0 2.1 1 1 1 2 2 2 2 Regulator of volume decrease after cellular swelling Med25_VWA PF11265.8 KIY63535.1 - 1.9e-07 31.1 0.0 3.3e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Mediator complex subunit 25 von Willebrand factor type A Lant_dehydr_N PF04738.13 KIY63536.1 - 0.0013 17.0 1.1 0.0018 16.5 1.1 1.1 1 0 0 1 1 1 1 Lantibiotic dehydratase, N terminus Abhydrolase_1 PF00561.20 KIY63537.1 - 1.8e-06 27.8 0.0 0.0077 15.9 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KIY63537.1 - 8.9e-05 22.0 0.0 0.00022 20.8 0.0 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KIY63537.1 - 0.001 18.4 0.1 0.015 14.6 0.0 2.5 2 1 0 3 3 3 1 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 KIY63537.1 - 0.017 15.2 0.0 0.047 13.8 0.0 1.8 2 0 0 2 2 2 0 TAP-like protein PITH PF06201.13 KIY63538.1 - 6.1e-39 133.7 0.0 7.4e-39 133.4 0.0 1.1 1 0 0 1 1 1 1 PITH domain DUF4131 PF13567.6 KIY63539.1 - 1.5 8.4 4.8 2.1 8.0 0.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) p450 PF00067.22 KIY63540.1 - 2.1e-58 198.2 0.0 3.8e-58 197.3 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 PHD PF00628.29 KIY63541.1 - 3.4e-07 30.0 10.0 6e-07 29.2 10.0 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 KIY63541.1 - 0.012 15.8 2.8 0.026 14.8 2.8 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain Prok-RING_1 PF14446.6 KIY63541.1 - 0.55 10.2 5.4 1.1 9.3 5.4 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 UBX PF00789.20 KIY63542.1 - 2.9e-08 33.8 0.3 4.9e-08 33.1 0.3 1.3 1 0 0 1 1 1 1 UBX domain PS_Dcarbxylase PF02666.15 KIY63542.1 - 0.062 12.8 0.0 0.12 11.9 0.0 1.7 1 1 1 2 2 2 0 Phosphatidylserine decarboxylase ThiF PF00899.21 KIY63543.1 - 1.9e-61 207.6 0.0 2.8e-61 207.0 0.0 1.1 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 KIY63543.1 - 1.9e-10 41.2 0.0 4.1e-09 36.9 0.0 2.2 2 0 0 2 2 2 1 Rhodanese-like domain Shikimate_DH PF01488.20 KIY63543.1 - 0.0059 16.7 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 KIY63543.1 - 0.028 14.9 0.0 0.16 12.4 0.0 2.0 2 0 0 2 2 2 0 Putative NAD(P)-binding Sacchrp_dh_NADP PF03435.18 KIY63543.1 - 0.042 14.1 0.2 0.17 12.2 0.1 2.0 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain PglD_N PF17836.1 KIY63543.1 - 0.077 13.6 0.0 0.6 10.8 0.1 2.1 2 0 0 2 2 2 0 PglD N-terminal domain AlaDh_PNT_C PF01262.21 KIY63543.1 - 0.089 12.1 0.1 1.1 8.5 0.0 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain ANAPC10 PF03256.16 KIY63544.1 - 4.5e-52 176.4 0.0 5.5e-52 176.1 0.0 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.25 KIY63544.1 - 9.9e-06 25.7 0.0 7.9e-05 22.8 0.0 2.1 1 1 1 2 2 2 1 F5/8 type C domain An_peroxidase PF03098.15 KIY63545.1 - 2.8e-15 55.9 0.0 4.6e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 Animal haem peroxidase ParA PF10609.9 KIY63546.1 - 5.7e-80 268.3 0.1 6.7e-80 268.1 0.1 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KIY63546.1 - 1.7e-15 57.2 0.0 4.3e-15 55.9 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 KIY63546.1 - 5.2e-12 46.0 0.1 1.4e-11 44.7 0.1 1.6 1 1 0 1 1 1 1 AAA domain MipZ PF09140.11 KIY63546.1 - 2.6e-07 30.2 0.0 4.3e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 KIY63546.1 - 6.5e-07 28.8 1.4 0.00025 20.3 0.6 2.3 2 0 0 2 2 2 2 Anion-transporting ATPase CLP1_P PF16575.5 KIY63546.1 - 0.00014 21.7 0.0 0.00022 21.1 0.0 1.3 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_26 PF13500.6 KIY63546.1 - 0.00028 20.7 1.7 0.012 15.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain Fer4_NifH PF00142.18 KIY63546.1 - 0.0021 17.5 0.2 0.0067 15.9 0.0 1.8 2 1 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family VirC1 PF07015.11 KIY63546.1 - 0.0042 16.4 0.1 0.012 15.0 0.1 1.7 2 0 0 2 2 2 1 VirC1 protein AAA_25 PF13481.6 KIY63546.1 - 0.0048 16.5 0.1 0.0091 15.6 0.1 1.5 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KIY63546.1 - 0.023 14.6 0.4 1.1 9.1 0.3 2.1 2 0 0 2 2 2 0 RsgA GTPase MeaB PF03308.16 KIY63546.1 - 0.1 11.6 0.1 0.14 11.1 0.1 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB CBP_BcsQ PF06564.12 KIY63546.1 - 0.13 11.7 1.6 0.16 11.4 0.5 1.6 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ Ribosomal_L33 PF00471.20 KIY63547.1 - 5e-05 23.7 0.0 6.6e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L33 COX6B PF02297.17 KIY63550.1 - 2.9e-22 78.7 0.9 3.9e-22 78.3 0.9 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Pet191_N PF10203.9 KIY63550.1 - 0.021 15.1 0.2 0.031 14.6 0.2 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 RP1-2 PF12042.8 KIY63550.1 - 0.029 14.3 0.2 0.029 14.3 0.2 1.9 2 0 0 2 2 2 0 Tubuliform egg casing silk strands structural domain FA_hydroxylase PF04116.13 KIY63552.1 - 1e-22 80.9 21.7 1e-22 80.9 21.7 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF1270 PF06900.11 KIY63552.1 - 0.13 12.6 0.5 0.13 12.6 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1270) TatC PF00902.18 KIY63552.1 - 0.43 10.4 4.3 8.9 6.1 4.4 2.4 1 1 0 1 1 1 0 Sec-independent protein translocase protein (TatC) Syntaxin-6_N PF09177.11 KIY63553.1 - 6.7e-21 74.7 1.6 2.7e-20 72.8 0.1 2.2 2 0 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.19 KIY63553.1 - 2.4e-07 30.6 0.7 6.9e-07 29.2 0.0 2.1 3 0 0 3 3 3 1 SNARE domain Use1 PF09753.9 KIY63553.1 - 0.03 14.0 0.0 0.043 13.5 0.0 1.2 1 0 0 1 1 1 0 Membrane fusion protein Use1 Prominin PF05478.11 KIY63553.1 - 0.069 11.1 0.0 0.093 10.7 0.0 1.2 1 0 0 1 1 1 0 Prominin Spc7 PF08317.11 KIY63553.1 - 0.15 10.9 0.1 6.7 5.5 0.0 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein RNA_pol_A_CTD PF03118.15 KIY63553.1 - 0.17 11.6 0.1 0.33 10.7 0.1 1.5 1 0 0 1 1 1 0 Bacterial RNA polymerase, alpha chain C terminal domain PilJ PF13675.6 KIY63553.1 - 0.23 11.5 5.0 0.96 9.5 0.3 2.3 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Ribosomal_L16 PF00252.18 KIY63554.1 - 1.8e-38 131.5 0.1 2.3e-38 131.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Med9 PF07544.13 KIY63554.1 - 0.22 11.6 0.0 0.33 11.0 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Robl_LC7 PF03259.17 KIY63555.1 - 5.8e-09 35.6 0.0 9.2e-09 35.0 0.0 1.3 1 0 0 1 1 1 1 Roadblock/LC7 domain Ribosomal_L18p PF00861.22 KIY63555.1 - 0.11 12.9 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast TMEM223 PF14640.6 KIY63557.1 - 0.12 12.6 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 223 Pyr_redox_2 PF07992.14 KIY63558.1 - 7.4e-54 183.0 0.1 8.6e-54 182.8 0.1 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KIY63558.1 - 1.2e-18 67.5 0.3 7.5e-15 55.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIY63558.1 - 2e-17 63.5 0.4 2.6e-14 53.6 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KIY63558.1 - 1.4e-05 24.4 2.1 0.005 16.0 0.1 3.8 4 0 0 4 4 4 1 Glucose inhibited division protein A Thi4 PF01946.17 KIY63558.1 - 3.7e-05 23.1 0.1 0.00027 20.2 0.0 2.2 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 KIY63558.1 - 4.3e-05 23.3 0.2 0.0027 17.4 0.0 2.6 1 1 1 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KIY63558.1 - 8.1e-05 22.8 0.3 0.0062 16.7 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KIY63558.1 - 0.00012 21.3 0.2 0.0032 16.6 0.0 2.6 3 0 0 3 3 3 1 FAD binding domain NAD_binding_7 PF13241.6 KIY63558.1 - 0.00015 22.1 0.0 0.076 13.5 0.0 3.0 2 2 0 2 2 2 1 Putative NAD(P)-binding FAD_oxidored PF12831.7 KIY63558.1 - 0.00026 20.5 0.0 0.0073 15.7 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KIY63558.1 - 0.0015 17.8 0.2 0.033 13.4 0.0 2.4 2 1 1 3 3 3 1 FAD binding domain Trp_halogenase PF04820.14 KIY63558.1 - 0.0032 16.4 0.8 0.059 12.2 0.2 2.7 2 1 1 3 3 3 1 Tryptophan halogenase HI0933_like PF03486.14 KIY63558.1 - 0.0082 14.9 0.4 0.054 12.2 0.1 2.3 3 0 0 3 3 3 1 HI0933-like protein Shikimate_DH PF01488.20 KIY63558.1 - 0.0085 16.2 0.2 6 6.9 0.0 3.3 4 0 0 4 4 4 1 Shikimate / quinate 5-dehydrogenase K_oxygenase PF13434.6 KIY63558.1 - 0.012 14.8 0.1 0.13 11.4 0.0 2.6 2 1 1 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) F420_oxidored PF03807.17 KIY63558.1 - 0.018 15.6 0.0 1.4 9.5 0.0 2.9 3 0 0 3 3 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_9 PF13454.6 KIY63558.1 - 0.11 12.5 0.1 27 4.7 0.0 2.8 3 0 0 3 3 3 0 FAD-NAD(P)-binding ApbA PF02558.16 KIY63558.1 - 0.35 10.5 2.5 17 5.1 0.0 2.7 3 1 0 3 3 3 0 Ketopantoate reductase PanE/ApbA Aldo_ket_red PF00248.21 KIY63559.1 - 4.5e-39 134.4 0.0 5.5e-39 134.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DMA PF03474.14 KIY63559.1 - 0.019 14.5 0.1 0.16 11.6 0.1 2.3 2 0 0 2 2 2 0 DMRTA motif AAA PF00004.29 KIY63560.1 - 4.3e-54 182.5 0.0 6.1e-43 146.4 0.0 2.8 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 KIY63560.1 - 1.3e-24 86.4 0.5 4.4e-24 84.7 0.5 2.0 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_lid_3 PF17862.1 KIY63560.1 - 6e-15 54.8 1.6 4.6e-10 39.1 0.5 2.5 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 KIY63560.1 - 1.6e-10 41.7 8.0 9.1e-05 22.9 0.1 4.3 4 2 0 5 5 4 2 AAA ATPase domain AAA_22 PF13401.6 KIY63560.1 - 2.7e-08 34.2 3.1 0.0043 17.3 0.3 4.9 3 2 1 5 5 4 2 AAA domain RuvB_N PF05496.12 KIY63560.1 - 1.3e-05 25.0 0.0 0.0037 17.0 0.0 3.1 3 0 0 3 3 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 KIY63560.1 - 2.8e-05 24.2 0.0 0.32 11.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KIY63560.1 - 3.9e-05 24.2 0.0 0.17 12.5 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_5 PF07728.14 KIY63560.1 - 7.6e-05 22.7 0.0 0.57 10.2 0.0 3.3 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) Rad17 PF03215.15 KIY63560.1 - 0.00027 20.9 0.0 0.18 11.7 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain TIP49 PF06068.13 KIY63560.1 - 0.00034 19.9 0.1 0.065 12.4 0.0 2.2 2 0 0 2 2 2 1 TIP49 P-loop domain TsaE PF02367.17 KIY63560.1 - 0.00051 20.0 0.0 0.64 10.0 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 KIY63560.1 - 0.00053 20.2 0.0 0.061 13.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.14 KIY63560.1 - 0.00067 19.8 0.0 0.078 13.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) NACHT PF05729.12 KIY63560.1 - 0.00074 19.5 0.5 1.9 8.4 0.1 3.6 3 1 0 3 3 3 1 NACHT domain Mg_chelatase PF01078.21 KIY63560.1 - 0.00081 18.8 0.0 0.67 9.3 0.0 2.7 3 0 0 3 3 2 1 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 KIY63560.1 - 0.001 19.6 0.2 0.19 12.2 0.1 2.9 2 1 0 2 2 2 1 ABC transporter Bac_DnaA PF00308.18 KIY63560.1 - 0.001 19.0 0.0 0.093 12.5 0.0 2.3 2 0 0 2 2 2 1 Bacterial dnaA protein IstB_IS21 PF01695.17 KIY63560.1 - 0.0011 18.7 0.0 1.3 8.8 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein Sigma54_activ_2 PF14532.6 KIY63560.1 - 0.0011 19.0 0.0 0.37 10.9 0.0 2.9 3 0 0 3 3 2 1 Sigma-54 interaction domain RNA_helicase PF00910.22 KIY63560.1 - 0.0016 18.8 0.0 0.84 10.1 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_7 PF12775.7 KIY63560.1 - 0.0025 17.3 0.0 0.41 10.1 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region Zeta_toxin PF06414.12 KIY63560.1 - 0.0027 17.0 0.1 2.6 7.3 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_25 PF13481.6 KIY63560.1 - 0.0033 17.0 1.2 1 8.9 0.2 3.8 3 1 1 4 4 4 1 AAA domain NTPase_1 PF03266.15 KIY63560.1 - 0.006 16.5 0.1 0.31 10.9 0.0 2.6 2 0 0 2 2 2 1 NTPase AAA_29 PF13555.6 KIY63560.1 - 0.0066 16.2 0.1 0.099 12.4 0.1 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF2075 PF09848.9 KIY63560.1 - 0.0079 15.5 0.0 3.6 6.7 0.0 2.2 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.18 KIY63560.1 - 0.0088 15.8 0.0 0.87 9.3 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Sigma54_activat PF00158.26 KIY63560.1 - 0.01 15.5 0.0 1.7 8.3 0.0 2.6 2 1 0 2 2 2 0 Sigma-54 interaction domain TniB PF05621.11 KIY63560.1 - 0.015 14.8 0.0 2.9 7.2 0.0 3.6 4 0 0 4 4 3 0 Bacterial TniB protein DUF815 PF05673.13 KIY63560.1 - 0.015 14.5 0.0 0.66 9.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_3 PF07726.11 KIY63560.1 - 0.017 15.0 0.0 1.4 8.8 0.0 3.0 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KIY63560.1 - 0.019 14.7 0.7 4.6 6.9 0.1 2.5 2 1 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KIY63560.1 - 0.02 14.1 0.0 3.3 6.8 0.0 2.7 2 0 0 2 2 2 0 NB-ARC domain PRK PF00485.18 KIY63560.1 - 0.027 14.2 0.0 0.099 12.4 0.0 1.9 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_19 PF13245.6 KIY63560.1 - 0.06 13.7 0.0 1.8 8.9 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_17 PF13207.6 KIY63560.1 - 0.066 13.6 0.6 0.35 11.3 0.1 2.3 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 KIY63560.1 - 0.089 12.7 0.1 1.6 8.6 0.0 2.6 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_28 PF13521.6 KIY63560.1 - 0.11 12.7 0.0 4.8 7.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain SKI PF01202.22 KIY63560.1 - 0.11 12.6 0.1 4.2 7.5 0.0 2.4 2 0 0 2 2 2 0 Shikimate kinase Cytidylate_kin2 PF13189.6 KIY63560.1 - 0.14 12.3 0.0 0.33 11.0 0.0 1.6 1 0 0 1 1 1 0 Cytidylate kinase-like family ATPase_2 PF01637.18 KIY63560.1 - 0.15 12.0 0.1 13 5.6 0.0 2.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea ATPase PF06745.13 KIY63560.1 - 0.17 11.2 0.2 8 5.7 0.0 2.6 3 0 0 3 3 3 0 KaiC GIT_SHD PF08518.11 KIY63561.1 - 1.3e-26 91.9 5.1 1e-13 50.7 0.7 2.6 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT ATG16 PF08614.11 KIY63561.1 - 0.07 13.3 32.3 0.025 14.8 13.4 3.5 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) Lebercilin PF15619.6 KIY63561.1 - 0.081 12.6 35.2 0.044 13.4 18.7 3.7 3 1 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Golgin_A5 PF09787.9 KIY63561.1 - 0.21 11.0 26.4 0.9 8.9 1.9 2.7 2 0 0 2 2 2 0 Golgin subfamily A member 5 DUF2935 PF11155.8 KIY63561.1 - 0.39 11.0 1.8 4.4 7.7 0.0 3.3 2 1 2 4 4 4 0 Domain of unknown function (DUF2935) EzrA PF06160.12 KIY63561.1 - 2.7 6.1 17.4 0.99 7.5 3.8 3.1 3 0 0 3 3 3 0 Septation ring formation regulator, EzrA LRR_4 PF12799.7 KIY63562.1 - 0.014 15.8 3.7 16 6.1 0.0 4.1 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) FBD PF08387.10 KIY63562.1 - 0.12 12.3 0.0 1.1 9.2 0.0 2.5 3 0 0 3 3 3 0 FBD NdhN PF11909.8 KIY63562.1 - 0.15 11.7 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 NADH-quinone oxidoreductase cyanobacterial subunit N AMPKBI PF04739.15 KIY63563.1 - 2.3e-24 85.5 5.5 2e-23 82.4 4.1 3.0 2 1 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interaction domain AMPK1_CBM PF16561.5 KIY63563.1 - 8.1e-16 58.0 0.0 1.4e-15 57.3 0.0 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase DUF2457 PF10446.9 KIY63563.1 - 2.1 7.4 5.4 4.4 6.3 5.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Adaptin_N PF01602.20 KIY63566.1 - 3.4e-20 72.1 1.1 6.2e-20 71.2 1.1 1.5 1 1 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.6 KIY63566.1 - 0.0015 18.9 0.3 0.25 11.8 0.7 3.7 2 2 1 3 3 3 1 HEAT repeats Cnd1 PF12717.7 KIY63566.1 - 0.0066 16.5 0.1 2.3 8.2 0.1 2.7 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 RabGAP-TBC PF00566.18 KIY63567.1 - 5.3e-39 134.1 0.0 7.3e-39 133.6 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain ER_lumen_recept PF00810.18 KIY63567.1 - 0.13 13.1 0.1 2.8 8.8 0.0 2.1 2 0 0 2 2 2 0 ER lumen protein retaining receptor UQ_con PF00179.26 KIY63569.1 - 4e-38 130.2 0.0 5.5e-38 129.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Pantoate_transf PF02548.15 KIY63570.1 - 2.8e-104 348.1 0.2 3.2e-104 347.9 0.2 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 KIY63570.1 - 7.4e-06 25.6 0.1 1.8e-05 24.3 0.0 1.6 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase p450 PF00067.22 KIY63571.1 - 1.4e-81 274.6 0.0 2e-81 274.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 KIY63571.1 - 9.3e-25 87.5 0.0 1.7e-24 86.6 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KIY63571.1 - 3.7e-22 79.1 0.1 8.7e-22 77.9 0.1 1.7 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KIY63571.1 - 2.5e-10 41.0 0.0 5.9e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 KIY63571.1 - 0.12 12.6 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 Flavodoxin domain SnoaL_2 PF12680.7 KIY63574.1 - 0.00079 20.0 0.0 0.0012 19.4 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain WD40 PF00400.32 KIY63575.1 - 3.9e-41 138.3 11.3 4.5e-07 30.5 0.1 7.6 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY63575.1 - 1.3e-14 54.3 0.1 0.016 15.5 0.0 5.6 4 2 3 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain PRP4 PF08799.11 KIY63575.1 - 5.4e-13 48.2 2.6 9.7e-13 47.4 2.6 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Ge1_WD40 PF16529.5 KIY63575.1 - 3.1e-05 23.1 0.1 0.24 10.3 0.1 3.9 2 2 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KIY63575.1 - 0.0002 20.8 0.0 1.1 8.5 0.0 3.2 3 0 0 3 3 3 2 WD40-like domain Nup160 PF11715.8 KIY63575.1 - 0.0072 15.0 0.1 2.6 6.6 0.0 3.5 4 0 0 4 4 4 2 Nucleoporin Nup120/160 Nbas_N PF15492.6 KIY63575.1 - 0.025 13.9 0.1 0.76 9.0 0.0 2.7 3 0 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal RNA_ligase PF09414.10 KIY63576.1 - 9.1e-27 94.3 0.0 1.5e-26 93.6 0.0 1.3 1 0 0 1 1 1 1 RNA ligase AAA_33 PF13671.6 KIY63576.1 - 7.6e-13 48.8 1.7 7.1e-06 26.2 0.1 3.7 2 2 1 3 3 3 2 AAA domain DSPc PF00782.20 KIY63576.1 - 3.1e-05 23.8 0.0 0.00019 21.2 0.0 2.2 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KIY63576.1 - 3.5e-05 23.9 0.0 0.00015 21.8 0.0 2.0 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 KIY63576.1 - 0.00012 21.8 0.0 0.00022 20.9 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 KIY63576.1 - 0.0038 16.8 0.0 0.0081 15.8 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family AAA_22 PF13401.6 KIY63576.1 - 0.011 16.0 0.0 0.029 14.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain 6PF2K PF01591.18 KIY63576.1 - 0.029 13.7 0.0 0.39 10.0 0.0 2.2 2 0 0 2 2 2 0 6-phosphofructo-2-kinase AAA_18 PF13238.6 KIY63576.1 - 0.042 14.4 0.0 0.09 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KIY63576.1 - 0.052 13.5 0.0 0.096 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 KIY63576.1 - 0.099 12.4 0.0 0.3 10.8 0.0 1.8 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_28 PF13521.6 KIY63576.1 - 0.14 12.4 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.10 KIY63576.1 - 0.17 11.3 0.1 3.2 7.1 0.1 2.1 1 1 0 2 2 2 0 Chromatin associated protein KTI12 PI-PLC-X PF00388.19 KIY63577.1 - 3.4e-37 127.2 0.0 5.2e-37 126.6 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KIY63577.1 - 9.9e-27 93.6 0.0 1.7e-26 92.8 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 KIY63577.1 - 0.011 16.0 0.2 0.03 14.6 0.1 1.7 2 0 0 2 2 2 0 C2 domain PX PF00787.24 KIY63578.1 - 7e-16 58.2 0.1 1.4e-15 57.2 0.1 1.5 1 0 0 1 1 1 1 PX domain SPR1 PF15356.6 KIY63578.1 - 0.83 10.2 7.4 7.7 7.1 0.4 2.4 2 0 0 2 2 2 0 Psoriasis susceptibility locus 2 Aminotran_1_2 PF00155.21 KIY63579.1 - 1.6e-67 228.2 0.0 1.9e-67 228.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KIY63579.1 - 0.00076 18.9 0.0 0.0012 18.2 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 KIY63579.1 - 0.00093 17.8 0.0 0.0027 16.3 0.0 1.7 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 KIY63579.1 - 0.0039 16.5 0.0 0.0054 16.1 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 KIY63579.1 - 0.0054 15.7 0.0 0.15 10.9 0.0 2.3 3 0 0 3 3 3 1 Aminotransferase class-V DUF2240 PF09999.9 KIY63579.1 - 0.039 13.6 0.0 0.078 12.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2240) NPV_P10 PF05531.12 KIY63580.1 - 0.0049 17.3 0.3 0.021 15.3 0.2 2.0 1 1 1 2 2 2 1 Nucleopolyhedrovirus P10 protein LMBR1 PF04791.16 KIY63580.1 - 0.015 14.2 0.2 0.019 13.9 0.2 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Spc7 PF08317.11 KIY63580.1 - 0.017 14.0 0.3 0.023 13.6 0.3 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Cortex-I_coil PF09304.10 KIY63580.1 - 0.019 15.2 1.1 0.35 11.1 0.1 2.1 1 1 1 2 2 2 0 Cortexillin I, coiled coil DUF4600 PF15372.6 KIY63580.1 - 0.021 15.2 0.0 0.047 14.1 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4600) Rootletin PF15035.6 KIY63580.1 - 0.031 14.3 0.2 0.041 13.9 0.2 1.1 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Fib_alpha PF08702.10 KIY63580.1 - 0.032 14.4 0.2 0.04 14.1 0.2 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Dynactin_p22 PF07426.11 KIY63580.1 - 0.063 13.1 0.1 0.18 11.6 0.0 1.7 2 0 0 2 2 2 0 Dynactin subunit p22 Calpain_inhib PF00748.19 KIY63580.1 - 0.076 13.5 0.1 0.13 12.8 0.1 1.3 1 0 0 1 1 1 0 Calpain inhibitor HisKA_3 PF07730.13 KIY63580.1 - 0.083 13.4 3.2 3.2 8.3 0.1 2.4 1 1 1 2 2 2 0 Histidine kinase WXG100 PF06013.12 KIY63580.1 - 0.094 13.0 0.4 3.5 7.9 0.0 2.2 2 0 0 2 2 2 0 Proteins of 100 residues with WXG TMPIT PF07851.13 KIY63580.1 - 0.11 11.8 5.0 3.5 6.8 1.3 2.2 2 0 0 2 2 2 0 TMPIT-like protein Erythro-docking PF09277.11 KIY63580.1 - 0.45 10.5 4.7 11 6.0 0.1 2.6 1 1 1 2 2 2 0 Erythronolide synthase, docking zf-Nse PF11789.8 KIY63582.1 - 1.3e-14 53.7 0.0 2.2e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 KIY63582.1 - 0.002 18.1 0.1 0.0043 17.0 0.1 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KIY63582.1 - 0.013 15.4 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-MIZ PF02891.20 KIY63582.1 - 0.021 14.6 0.2 0.047 13.4 0.2 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger DUF4547 PF15080.6 KIY63582.1 - 0.044 13.4 0.1 0.071 12.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4547) MTHFR PF02219.17 KIY63583.1 - 4.8e-108 360.8 0.0 6.4e-108 360.4 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase PIN_9 PF18477.1 KIY63583.1 - 0.02 15.2 0.0 0.052 13.9 0.0 1.7 1 0 0 1 1 1 0 PIN like domain Glyco_hydro_18 PF00704.28 KIY63585.1 - 2.5e-11 43.9 0.6 3.5e-11 43.4 0.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 VPS9 PF02204.18 KIY63586.1 - 8.1e-33 112.8 0.0 1.4e-32 111.9 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 KIY63586.1 - 3.3e-15 56.1 0.2 1.3e-14 54.2 0.2 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) CUE PF02845.16 KIY63586.1 - 3.5e-09 36.2 0.1 1.2e-08 34.4 0.0 2.0 2 0 0 2 2 2 1 CUE domain DMA PF03474.14 KIY63586.1 - 4.5e-06 26.2 0.0 8.2e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 DMRTA motif HEAT_2 PF13646.6 KIY63587.1 - 3.9e-06 27.2 0.3 0.00074 19.9 0.1 3.7 3 1 1 4 4 4 2 HEAT repeats HEAT PF02985.22 KIY63587.1 - 0.0017 18.5 0.5 4 8.0 0.1 4.2 5 0 0 5 5 5 2 HEAT repeat Cnd1 PF12717.7 KIY63587.1 - 0.0035 17.4 0.0 0.019 15.0 0.0 2.2 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KIY63587.1 - 0.024 15.1 0.3 0.13 12.8 0.0 2.6 2 0 0 2 2 2 0 HEAT-like repeat ATP-synt_E PF05680.12 KIY63587.1 - 0.53 10.6 2.1 1.5 9.2 0.1 2.5 2 0 0 2 2 2 0 ATP synthase E chain SWIM PF04434.17 KIY63589.1 - 0.00013 21.5 0.1 0.00029 20.4 0.1 1.6 1 0 0 1 1 1 1 SWIM zinc finger zf-RING_2 PF13639.6 KIY63589.1 - 0.0016 18.7 5.7 0.0016 18.7 5.7 2.0 2 1 0 2 2 2 1 Ring finger domain zf-RING_9 PF13901.6 KIY63589.1 - 0.077 13.0 4.2 0.14 12.1 4.2 1.4 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon FANCL_C PF11793.8 KIY63589.1 - 0.16 12.1 7.6 0.22 11.7 5.5 2.1 2 0 0 2 2 2 0 FANCL C-terminal domain C1_1 PF00130.22 KIY63589.1 - 0.58 10.1 5.0 0.21 11.5 1.4 1.9 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) AFT PF08731.11 KIY63589.1 - 1.3 9.5 6.2 6.8 7.1 6.1 2.2 1 1 0 1 1 1 0 Transcription factor AFT zf-C3HC4 PF00097.25 KIY63589.1 - 2.5 8.1 12.6 0.15 11.9 5.1 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-dskA_traR PF01258.17 KIY63589.1 - 2.6 8.1 6.6 0.83 9.6 1.1 2.6 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger zf-C3HC4_2 PF13923.6 KIY63589.1 - 4.5 7.2 6.3 1.2e+02 2.6 6.6 2.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KIY63589.1 - 4.9 6.8 11.0 0.56 9.9 4.9 2.4 3 0 0 3 3 3 0 Zinc-ribbon, C4HC2 type YhfH PF14149.6 KIY63589.1 - 5.1 7.2 10.9 5 7.2 1.0 2.9 2 1 1 3 3 3 0 YhfH-like protein ubiquitin PF00240.23 KIY63590.1 - 3.4e-34 116.4 0.5 3.4e-34 116.4 0.5 1.6 2 0 0 2 2 2 1 Ubiquitin family Ribosomal_S27 PF01599.19 KIY63590.1 - 1e-26 92.8 2.0 1e-26 92.8 2.0 1.9 2 0 0 2 2 2 1 Ribosomal protein S27a Rad60-SLD PF11976.8 KIY63590.1 - 3.6e-16 58.8 0.6 7.9e-16 57.7 0.6 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KIY63590.1 - 2.8e-05 24.5 0.4 0.00014 22.2 0.1 2.2 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 KIY63590.1 - 0.00029 20.9 0.5 0.00065 19.8 0.5 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 KIY63590.1 - 0.0072 16.7 1.0 0.012 15.9 0.0 1.7 1 1 1 2 2 2 1 Ubiquitin-like domain DUF2407 PF10302.9 KIY63590.1 - 0.0073 16.8 0.7 0.01 16.4 0.7 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain TBK1_ULD PF18396.1 KIY63590.1 - 0.0074 16.2 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_4 PF18036.1 KIY63590.1 - 0.02 14.9 1.1 5.9 7.0 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-like domain IBR PF01485.21 KIY63590.1 - 0.035 14.3 0.5 0.06 13.6 0.5 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain DUF4925 PF16272.5 KIY63590.1 - 0.073 12.5 0.2 0.099 12.1 0.2 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4925) DUF971 PF06155.12 KIY63590.1 - 0.16 12.7 0.2 0.33 11.6 0.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF971) F-box-like PF12937.7 KIY63592.1 - 0.0011 18.8 12.6 0.011 15.6 7.7 3.5 2 1 0 2 2 2 1 F-box-like COesterase PF00135.28 KIY63593.1 - 4.2e-60 204.1 0.0 7e-60 203.3 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Bin3 PF06859.12 KIY63594.1 - 3.4e-31 108.1 0.0 4.8e-31 107.6 0.0 1.2 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_31 PF13847.6 KIY63594.1 - 1.2e-10 41.4 0.0 1.8e-07 31.1 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 KIY63594.1 - 8.3e-10 39.2 0.0 2.2e-06 28.3 0.1 2.2 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 KIY63594.1 - 2.2e-07 30.9 0.0 2.8e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIY63594.1 - 1.8e-06 28.6 0.0 4.2e-05 24.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIY63594.1 - 1.9e-06 28.4 0.1 0.00074 20.1 0.1 2.2 1 1 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.17 KIY63594.1 - 3.9e-05 23.2 0.0 0.0001 21.8 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase CMAS PF02353.20 KIY63594.1 - 0.0045 16.3 0.1 2.4 7.4 0.1 2.1 2 0 0 2 2 2 2 Mycolic acid cyclopropane synthetase MTS PF05175.14 KIY63594.1 - 0.0048 16.5 0.0 0.011 15.3 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_18 PF12847.7 KIY63594.1 - 0.0088 16.0 0.0 0.014 15.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 KIY63594.1 - 0.04 12.8 0.0 0.14 11.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) PrmA PF06325.13 KIY63594.1 - 0.041 13.3 0.1 0.057 12.8 0.1 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 KIY63594.1 - 0.059 13.1 0.0 0.086 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Pox_MCEL PF03291.16 KIY63594.1 - 0.27 10.3 0.0 0.41 9.7 0.0 1.1 1 0 0 1 1 1 0 mRNA capping enzyme CorA PF01544.18 KIY63599.1 - 3.4e-06 26.6 4.7 6.1e-06 25.8 4.6 1.4 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Sm_multidrug_ex PF06695.11 KIY63599.1 - 0.06 14.0 0.2 0.31 11.7 0.0 2.2 1 1 1 2 2 2 0 Putative small multi-drug export protein DUF3961 PF13106.6 KIY63599.1 - 0.092 12.4 0.4 0.092 12.4 0.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3961) zf-MYND PF01753.18 KIY63600.1 - 2.8e-08 33.7 16.9 2.8e-08 33.7 16.9 1.9 2 0 0 2 2 2 1 MYND finger zf-C6H2 PF15801.5 KIY63600.1 - 0.4 11.0 12.2 0.87 9.9 12.2 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding DEAD PF00270.29 KIY63601.1 - 6.8e-38 130.2 0.1 1.3e-36 126.0 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIY63601.1 - 6.8e-25 87.6 0.1 2.1e-21 76.3 0.1 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 KIY63601.1 - 1.4e-05 25.2 0.0 0.00018 21.6 0.0 2.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit NmrA PF05368.13 KIY63602.1 - 1.5e-23 83.6 0.0 2.1e-23 83.1 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 KIY63602.1 - 8.8e-11 42.2 0.1 1.4e-08 35.0 0.0 2.2 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 KIY63602.1 - 1.7e-09 37.9 0.0 1.3e-08 34.9 0.0 2.1 1 1 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 KIY63602.1 - 0.00033 21.1 0.1 0.0007 20.0 0.0 1.6 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 KIY63602.1 - 0.0011 18.5 0.0 0.0021 17.6 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 KIY63602.1 - 0.0025 17.9 0.1 0.0046 17.1 0.1 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_4 PF07993.12 KIY63602.1 - 0.011 15.0 0.0 0.016 14.4 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein KR PF08659.10 KIY63602.1 - 0.012 15.5 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 KR domain Shikimate_DH PF01488.20 KIY63602.1 - 0.032 14.3 0.0 0.066 13.3 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.15 KIY63602.1 - 0.053 12.6 0.1 0.079 12.1 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein TrkA_N PF02254.18 KIY63602.1 - 0.057 13.7 0.4 0.18 12.1 0.2 1.8 2 0 0 2 2 2 0 TrkA-N domain GDP_Man_Dehyd PF16363.5 KIY63602.1 - 0.1 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KIY63603.1 - 2.3e-24 86.2 0.4 6.5e-22 78.2 0.4 2.2 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KIY63603.1 - 4.4e-08 33.2 0.1 1.2e-07 31.8 0.1 1.7 1 1 1 2 2 2 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KIY63603.1 - 5.6e-08 33.1 1.0 2.8e-07 30.9 0.2 2.0 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KIY63603.1 - 1.2e-05 24.9 0.1 1.8e-05 24.3 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 KIY63603.1 - 0.0002 21.8 0.2 0.00047 20.6 0.1 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 KIY63603.1 - 0.00028 20.4 0.1 0.00041 19.9 0.1 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase KR PF08659.10 KIY63603.1 - 0.0012 18.8 0.1 0.002 18.0 0.1 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 KIY63603.1 - 0.0019 17.4 0.0 0.0027 16.9 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 KIY63603.1 - 0.011 14.8 0.2 0.015 14.4 0.2 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Shikimate_DH PF01488.20 KIY63603.1 - 0.043 13.9 0.0 0.098 12.7 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pkinase PF00069.25 KIY63605.1 - 1e-49 169.3 0.0 1.3e-49 168.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY63605.1 - 4.2e-30 104.9 0.0 5.1e-30 104.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY63605.1 - 0.00027 20.4 0.0 0.00035 20.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KIY63605.1 - 0.004 17.1 0.0 0.078 12.9 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 KIY63605.1 - 0.087 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Rad60-SLD PF11976.8 KIY63606.1 - 0.0043 16.8 0.0 0.0083 15.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Pheromone PF08015.11 KIY63606.1 - 0.08 14.0 2.2 0.17 13.0 2.2 1.5 1 0 0 1 1 1 0 Fungal mating-type pheromone DUF374 PF04028.13 KIY63607.1 - 0.099 12.2 0.1 0.23 11.0 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF374) TFIIA PF03153.13 KIY63607.1 - 0.11 12.5 8.7 0.13 12.2 8.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Hormone_recep PF00104.30 KIY63607.1 - 0.13 11.9 0.4 0.23 11.0 0.4 1.4 1 0 0 1 1 1 0 Ligand-binding domain of nuclear hormone receptor T3SS_TC PF06511.11 KIY63607.1 - 1.6 8.1 5.4 2.2 7.6 5.4 1.2 1 0 0 1 1 1 0 Type III secretion systems tip complex components W2 PF02020.18 KIY63609.1 - 9.7e-20 70.5 0.8 5.3e-19 68.1 0.2 2.4 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Phage_TAC_11 PF11836.8 KIY63609.1 - 0.029 14.5 0.0 0.97 9.6 0.0 2.4 2 0 0 2 2 2 0 Phage tail tube protein, GTA-gp10 TetR PF13972.6 KIY63609.1 - 0.12 12.1 0.0 0.42 10.3 0.0 1.9 1 0 0 1 1 1 0 Bacterial transcriptional repressor PP2C PF00481.21 KIY63610.1 - 4.1e-61 206.9 0.0 7.4e-61 206.0 0.0 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C Speriolin_C PF15059.6 KIY63610.1 - 0.17 12.0 0.0 0.27 11.3 0.0 1.3 1 0 0 1 1 1 0 Speriolin C-terminus PP2C PF00481.21 KIY63611.1 - 7.8e-66 222.3 0.1 1.5e-50 172.3 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C Ferritin_2 PF13668.6 KIY63612.1 - 6.9e-32 110.5 4.4 1.2e-31 109.7 4.4 1.4 1 0 0 1 1 1 1 Ferritin-like domain DUF2383 PF09537.10 KIY63612.1 - 0.18 12.2 0.5 0.44 10.9 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF2383) PP2C PF00481.21 KIY63613.1 - 1.7e-41 142.5 0.0 4.1e-41 141.3 0.0 1.6 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.6 KIY63613.1 - 2.7e-41 139.1 64.4 4.1e-14 52.1 2.9 11.0 7 3 5 14 14 14 9 Leucine rich repeat LRR_4 PF12799.7 KIY63613.1 - 4.5e-35 119.1 71.7 5.3e-07 29.9 0.3 12.6 7 3 7 15 15 15 14 Leucine Rich repeats (2 copies) Guanylate_cyc PF00211.20 KIY63613.1 - 9.5e-25 87.3 0.0 2e-24 86.3 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_9 PF14580.6 KIY63613.1 - 1.4e-08 34.4 19.7 0.015 14.8 0.3 5.4 4 2 1 5 5 5 4 Leucine-rich repeat RA PF00788.23 KIY63613.1 - 9e-05 23.0 0.0 0.00021 21.9 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Ad_cyc_g-alpha PF08509.11 KIY63613.1 - 0.0016 18.1 0.1 0.0051 16.5 0.1 1.8 1 0 0 1 1 1 1 Adenylate cyclase G-alpha binding domain LRR_6 PF13516.6 KIY63613.1 - 0.022 14.8 48.1 1.2 9.4 1.1 13.4 15 0 0 15 15 15 0 Leucine Rich repeat LRR_5 PF13306.6 KIY63613.1 - 0.1 12.5 1.5 7.3 6.6 0.1 3.5 3 1 0 4 4 4 0 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 KIY63613.1 - 0.91 10.3 56.4 3 8.7 0.2 15.1 16 1 0 16 16 16 0 Leucine Rich Repeat HA2 PF04408.23 KIY63614.1 - 2.9e-19 69.3 0.0 8.3e-19 67.9 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KIY63614.1 - 1.3e-14 54.4 0.0 1.9e-13 50.7 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KIY63614.1 - 0.00018 21.3 0.1 0.0012 18.6 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase GPI-anchored PF10342.9 KIY63615.1 - 4.4e-07 30.6 0.3 6.8e-07 30.0 0.3 1.3 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family SpoIIE PF07228.12 KIY63616.1 - 2.1e-07 31.0 0.0 3.7e-07 30.2 0.0 1.6 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 KIY63616.1 - 2.7e-05 23.9 0.0 6.9e-05 22.6 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 KIY63616.1 - 3.4e-05 23.6 0.0 0.039 13.6 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C DuffyBP_N PF12377.8 KIY63616.1 - 0.0054 17.1 0.2 0.013 15.8 0.2 1.6 1 0 0 1 1 1 1 Duffy binding protein N terminal Pkinase PF00069.25 KIY63617.1 - 1.3e-55 188.6 0.0 1.6e-55 188.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY63617.1 - 3.2e-28 98.7 0.0 3.9e-28 98.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY63617.1 - 2e-09 37.2 0.0 3.1e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KIY63617.1 - 0.00023 21.1 0.0 0.00045 20.2 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KIY63617.1 - 0.0005 19.5 0.0 0.00084 18.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KIY63617.1 - 0.0071 15.2 0.0 0.0097 14.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 KIY63617.1 - 0.06 12.9 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.25 KIY63618.1 - 1.3e-58 198.4 0.0 1.7e-58 198.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY63618.1 - 5e-32 111.2 0.0 7.2e-32 110.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY63618.1 - 3.6e-06 26.5 0.0 6e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KIY63618.1 - 0.0005 20.1 0.1 0.0012 18.8 0.1 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 KIY63618.1 - 0.031 13.9 0.1 8.6 5.9 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 KIY63618.1 - 0.11 11.2 0.0 0.21 10.3 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase PH PF00169.29 KIY63618.1 - 0.18 12.4 0.0 0.35 11.4 0.0 1.5 1 0 0 1 1 1 0 PH domain RIO1 PF01163.22 KIY63618.1 - 0.18 11.4 0.0 0.47 10.0 0.0 1.6 2 0 0 2 2 2 0 RIO1 family Mid2 PF04478.12 KIY63619.1 - 0.0023 17.8 0.1 0.0031 17.4 0.1 1.1 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor He_PIG PF05345.12 KIY63620.1 - 1.3e-09 38.1 6.7 8.4e-06 25.9 0.2 4.6 5 0 0 5 5 5 2 Putative Ig domain ACP_syn_III_C PF08541.10 KIY63620.1 - 0.0015 18.7 0.0 0.0044 17.2 0.0 1.7 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal SepZ PF06066.11 KIY63620.1 - 0.081 13.1 0.3 0.23 11.7 0.3 1.7 1 0 0 1 1 1 0 SepZ DAO PF01266.24 KIY63621.1 - 4e-25 89.2 0.0 4.8e-25 88.9 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 KIY63621.1 - 9.2e-05 22.8 0.0 0.00017 22.0 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Pyr_redox_2 PF07992.14 KIY63621.1 - 0.0002 20.7 0.0 0.00089 18.6 0.0 2.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KIY63621.1 - 0.0037 16.6 0.0 0.008 15.5 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.6 KIY63621.1 - 0.0055 16.9 0.2 0.017 15.3 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KIY63621.1 - 0.011 15.1 0.0 0.018 14.3 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KIY63621.1 - 0.011 14.8 0.1 0.023 13.8 0.1 1.5 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox PF00070.27 KIY63621.1 - 0.011 16.2 0.7 0.026 15.1 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KIY63621.1 - 0.012 14.8 0.4 0.022 13.8 0.4 1.7 1 1 0 1 1 1 0 FAD binding domain FAD_binding_3 PF01494.19 KIY63621.1 - 0.013 14.8 0.0 0.024 13.9 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.7 KIY63621.1 - 0.051 12.9 0.3 0.89 8.8 0.1 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase CBFD_NFYB_HMF PF00808.23 KIY63622.1 - 2.1e-18 66.4 0.9 2.7e-18 66.0 0.9 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KIY63622.1 - 4.4e-05 23.9 0.3 6.3e-05 23.3 0.3 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAFII28 PF04719.14 KIY63622.1 - 0.0021 18.1 0.7 0.0032 17.5 0.7 1.2 1 0 0 1 1 1 1 hTAFII28-like protein conserved region DAO PF01266.24 KIY63623.1 - 2.5e-08 33.9 0.0 2.8e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 KIY63624.1 - 3.4e-25 89.4 0.0 4.2e-25 89.1 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIY63624.1 - 0.00014 21.2 0.0 0.00068 19.0 0.0 2.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KIY63624.1 - 0.00017 21.9 0.0 0.00034 21.0 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding NAD_binding_8 PF13450.6 KIY63624.1 - 0.005 17.0 0.2 0.017 15.3 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 KIY63624.1 - 0.0073 15.6 0.0 0.015 14.6 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 KIY63624.1 - 0.0086 15.2 0.7 0.024 13.7 0.6 1.9 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 KIY63624.1 - 0.011 16.2 0.7 0.025 15.1 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KIY63624.1 - 0.012 14.8 0.1 0.023 13.8 0.1 1.5 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_binding_3 PF01494.19 KIY63624.1 - 0.016 14.5 0.0 0.031 13.5 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 KIY63624.1 - 0.019 14.2 0.0 0.034 13.4 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KIY63624.1 - 0.047 13.0 0.3 0.88 8.8 0.1 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase F-box-like PF12937.7 KIY63625.1 - 3.2e-06 26.9 6.1 5.4e-05 23.0 6.1 2.5 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KIY63625.1 - 0.034 14.0 3.8 4 7.4 3.8 2.8 1 1 0 1 1 1 0 F-box domain LRR_4 PF12799.7 KIY63625.1 - 0.072 13.5 0.2 11 6.6 0.0 3.7 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) UBM PF14377.6 KIY63625.1 - 0.74 9.4 2.7 0.54 9.8 0.6 1.8 2 0 0 2 2 2 0 Ubiquitin binding region Lactamase_B PF00753.27 KIY63626.1 - 3.2e-11 43.6 0.2 7.8e-11 42.3 0.2 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KIY63626.1 - 0.00023 20.7 0.1 0.00048 19.7 0.1 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain EMC1_C PF07774.13 KIY63627.1 - 8.5e-74 247.8 0.0 1.4e-73 247.1 0.0 1.4 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 KIY63627.1 - 8.3e-07 28.8 2.5 0.0061 16.2 0.4 3.5 3 0 0 3 3 3 2 PQQ-like domain PQQ PF01011.21 KIY63627.1 - 8.4e-07 28.6 0.0 0.00048 19.9 0.0 3.1 2 0 0 2 2 2 2 PQQ enzyme repeat Oxidored_FMN PF00724.20 KIY63629.1 - 8.8e-100 334.3 0.0 1e-99 334.1 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Glycos_trans_3N PF02885.17 KIY63629.1 - 0.22 11.4 0.2 1.4 8.9 0.1 2.1 2 0 0 2 2 2 0 Glycosyl transferase family, helical bundle domain SF3b1 PF08920.10 KIY63630.1 - 2.3e-20 73.3 2.3 2.3e-20 73.3 2.3 2.7 1 1 1 2 2 2 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.6 KIY63630.1 - 3.2e-10 40.2 9.3 0.0047 17.3 0.2 7.7 4 2 5 9 9 8 2 HEAT repeats HEAT_EZ PF13513.6 KIY63630.1 - 2.8e-09 37.3 9.5 0.013 16.0 0.0 7.9 9 1 1 10 10 9 3 HEAT-like repeat HEAT PF02985.22 KIY63630.1 - 1.1e-06 28.4 14.4 1.2 9.6 0.0 10.0 12 0 0 12 12 10 1 HEAT repeat Vac14_Fab1_bd PF12755.7 KIY63630.1 - 1.1e-05 26.0 1.2 1.9 9.1 0.0 5.2 5 0 0 5 5 5 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KIY63630.1 - 1.7e-05 24.9 7.1 0.98 9.4 0.0 6.4 7 0 0 7 7 7 1 non-SMC mitotic condensation complex subunit 1 NUC173 PF08161.12 KIY63630.1 - 2.7e-05 23.9 0.9 1.8 8.2 0.0 4.9 4 1 1 5 5 5 2 NUC173 domain Adaptin_N PF01602.20 KIY63630.1 - 3.8e-05 22.5 1.1 0.022 13.3 0.1 3.0 2 1 0 2 2 2 2 Adaptin N terminal region UME PF08064.13 KIY63630.1 - 0.00026 20.9 0.1 0.61 10.0 0.0 4.8 5 1 1 6 6 6 1 UME (NUC010) domain CLASP_N PF12348.8 KIY63630.1 - 0.0008 19.0 1.7 0.57 9.7 0.0 3.6 3 1 0 3 3 3 1 CLASP N terminal DUF3385 PF11865.8 KIY63630.1 - 0.0021 18.0 0.6 0.58 10.1 0.1 4.6 4 2 0 4 4 4 1 Domain of unknown function (DUF3385) MMS19_C PF12460.8 KIY63630.1 - 0.038 13.1 0.1 52 2.8 0.0 4.1 2 2 0 3 3 3 0 RNAPII transcription regulator C-terminal DUF3110 PF11360.8 KIY63630.1 - 0.078 13.2 0.1 0.25 11.6 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3110) Dopey_N PF04118.14 KIY63630.1 - 0.21 10.7 2.1 12 4.9 0.0 3.4 4 0 0 4 4 4 0 Dopey, N-terminal DRIM PF07539.12 KIY63630.1 - 0.27 9.5 2.3 0.98 7.6 0.2 2.9 3 1 0 3 3 3 0 Down-regulated in metastasis Glyco_hydro_16 PF00722.21 KIY63631.1 - 1.3e-20 73.6 1.0 1.5e-20 73.4 1.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 OmpA PF00691.20 KIY63634.1 - 0.029 14.8 0.0 0.029 14.7 0.0 1.0 1 0 0 1 1 1 0 OmpA family AA_permease PF00324.21 KIY63635.1 - 1.8e-124 416.0 39.5 2.1e-124 415.7 39.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KIY63635.1 - 6.2e-36 124.1 44.0 7.5e-36 123.9 44.0 1.0 1 0 0 1 1 1 1 Amino acid permease DUF4231 PF14015.6 KIY63635.1 - 6 7.4 10.4 1.7e+02 2.7 0.0 4.3 3 1 1 4 4 4 0 Protein of unknown function (DUF4231) RhoGEF PF00621.20 KIY63637.1 - 6e-41 140.7 0.0 9.5e-41 140.0 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain LRR_8 PF13855.6 KIY63637.1 - 3.3e-07 30.0 0.3 0.018 14.8 0.1 2.7 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KIY63637.1 - 0.00021 21.6 0.2 0.099 13.1 0.2 3.1 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) PH PF00169.29 KIY63637.1 - 0.14 12.7 0.0 0.58 10.7 0.0 2.1 2 0 0 2 2 2 0 PH domain PAXNEB PF05625.11 KIY63638.1 - 7.7e-45 153.6 0.0 1.1e-44 153.2 0.0 1.1 1 0 0 1 1 1 1 PAXNEB protein ATPase PF06745.13 KIY63638.1 - 0.12 11.7 0.0 0.31 10.4 0.0 1.7 2 0 0 2 2 2 0 KaiC Phage_sheath_1 PF04984.14 KIY63638.1 - 0.16 11.8 0.1 3.9 7.3 0.0 2.2 2 0 0 2 2 2 0 Phage tail sheath protein subtilisin-like domain Peptidase_S24 PF00717.23 KIY63639.1 - 1.8e-08 34.2 0.0 2.8e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 KIY63639.1 - 1.7e-05 24.6 0.1 0.013 15.3 0.0 2.5 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 TPR_1 PF00515.28 KIY63640.1 - 4.3e-06 26.3 3.2 0.024 14.4 0.2 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KIY63640.1 - 0.00025 20.9 0.4 0.18 12.0 0.1 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 KIY63640.1 - 0.096 12.8 0.0 0.92 9.7 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Chisel PF15355.6 KIY63640.1 - 0.12 12.6 0.1 0.27 11.5 0.1 1.5 1 0 0 1 1 1 0 Stretch-responsive small skeletal muscle X protein, Chisel PXA PF02194.15 KIY63643.1 - 4.8e-44 150.5 1.2 4.8e-44 150.5 1.2 1.8 2 0 0 2 2 2 1 PXA domain Pkinase PF00069.25 KIY63644.1 - 1.7e-13 50.6 0.0 2.7e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY63644.1 - 0.0074 15.6 0.1 0.033 13.5 0.1 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Cyclin_C_2 PF16899.5 KIY63645.1 - 1.6e-15 57.3 0.1 1.5e-13 51.0 0.0 2.5 2 0 0 2 2 2 1 Cyclin C-terminal domain Cyclin_N PF00134.23 KIY63645.1 - 8.4e-09 35.3 0.1 2e-08 34.0 0.0 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Sde2_N_Ubi PF13019.6 KIY63645.1 - 0.03 14.2 6.7 0.073 12.9 3.5 2.4 2 1 0 2 2 2 0 Silencing defective 2 N-terminal ubiquitin domain DUF1764 PF08576.10 KIY63646.1 - 1.4e-22 80.5 10.8 1.9e-20 73.6 3.0 2.0 1 1 1 2 2 2 2 Eukaryotic protein of unknown function (DUF1764) DNApol_Exo PF18136.1 KIY63646.1 - 0.13 11.3 0.4 0.32 10.1 0.1 1.8 1 1 1 2 2 2 0 DNA mitochondrial polymerase exonuclease domain SRP-alpha_N PF04086.13 KIY63646.1 - 0.29 11.0 6.0 0.34 10.8 6.0 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Ribosomal_60s PF00428.19 KIY63646.1 - 0.55 10.9 9.3 0.18 12.4 2.7 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein ORC6 PF05460.13 KIY63646.1 - 2.6 7.2 9.4 3.1 7.0 9.4 1.0 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) ARID PF01388.21 KIY63647.1 - 3.6e-12 46.8 0.0 2e-10 41.2 0.0 2.6 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain MFS_1 PF07690.16 KIY63648.1 - 1.5e-23 83.3 20.6 2.2e-23 82.8 20.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Nodulin-like PF06813.13 KIY63648.1 - 6.2e-16 58.6 0.4 6.2e-16 58.6 0.4 2.1 3 0 0 3 3 3 1 Nodulin-like Cyclin_N PF00134.23 KIY63649.1 - 2.3e-38 130.8 0.2 3.7e-38 130.2 0.2 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KIY63649.1 - 1.1e-11 44.9 0.1 2.5e-11 43.7 0.1 1.7 1 1 0 1 1 1 1 Cyclin, C-terminal domain Rhomboid PF01694.22 KIY63651.1 - 2.1e-13 50.5 18.7 1.3e-12 48.0 16.8 2.9 2 1 0 2 2 2 1 Rhomboid family Methyltransf_16 PF10294.9 KIY63652.1 - 1.3e-19 70.6 0.0 2.4e-19 69.7 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 KIY63652.1 - 0.00018 22.1 0.0 0.0012 19.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIY63652.1 - 0.0047 16.8 0.0 0.0073 16.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIY63652.1 - 0.019 15.7 0.0 0.035 14.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 KIY63652.1 - 0.027 15.1 0.0 0.078 13.6 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.14 KIY63652.1 - 0.059 12.9 0.1 0.15 11.6 0.1 1.5 1 1 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.13 KIY63652.1 - 0.099 12.0 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 KIY63652.1 - 0.1 12.4 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MethyltransfD12 PF02086.15 KIY63652.1 - 0.16 11.6 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase F-box-like PF12937.7 KIY63653.1 - 1.2e-08 34.7 0.8 3.3e-08 33.3 0.8 1.9 1 0 0 1 1 1 1 F-box-like CENP-T_C PF15511.6 KIY63654.1 - 4.9e-07 29.9 0.0 5.9e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 KIY63654.1 - 3.4e-05 23.9 0.1 4.8e-05 23.5 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 KIY63654.1 - 0.0002 21.6 0.0 0.00026 21.3 0.0 1.3 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KIY63654.1 - 0.00085 19.6 0.1 0.0016 18.7 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KIY63654.1 - 0.00094 19.5 0.2 0.0011 19.4 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KIY63654.1 - 0.058 13.5 0.0 0.067 13.3 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KIY63654.1 - 0.14 12.2 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated Histone PF00125.24 KIY63655.1 - 3.2e-50 169.9 3.8 3.6e-50 169.7 3.8 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KIY63655.1 - 2.5e-05 24.6 0.1 4.1e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KIY63655.1 - 5.1e-05 23.4 0.1 9.9e-05 22.4 0.1 1.5 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 KIY63655.1 - 0.0002 21.9 1.6 0.00026 21.6 1.6 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 KIY63655.1 - 0.00068 19.9 0.1 0.0014 18.9 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.13 KIY63655.1 - 0.087 12.9 0.1 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 Bromodomain associated TFIID-31kDa PF02291.15 KIY63655.1 - 0.11 12.6 0.1 0.17 11.9 0.1 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Polyketide_cyc PF03364.20 KIY63656.1 - 1.2e-10 41.7 0.0 1.6e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 KIY63656.1 - 1.9e-07 31.4 0.2 2.5e-07 31.0 0.2 1.5 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport F-box-like PF12937.7 KIY63657.1 - 6.1e-06 26.0 0.2 1.9e-05 24.5 0.0 2.0 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 KIY63657.1 - 0.15 12.5 3.3 51 4.5 0.1 4.2 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) 3A PF00803.18 KIY63657.1 - 0.2 10.9 0.0 0.33 10.2 0.0 1.3 1 0 0 1 1 1 0 3A/RNA2 movement protein family RhoGAP PF00620.27 KIY63658.1 - 1.8e-35 122.0 0.0 5e-35 120.6 0.0 1.7 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.23 KIY63658.1 - 4.8e-15 55.6 1.7 1.7e-14 53.8 0.1 2.3 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SKA2 PF16740.5 KIY63658.1 - 0.026 14.3 2.7 0.085 12.6 2.7 1.9 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 Baculo_PEP_C PF04513.12 KIY63658.1 - 0.12 12.5 0.7 42 4.2 0.4 3.1 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.10 KIY63658.1 - 0.19 11.9 2.6 0.55 10.4 2.6 1.8 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family TBCA PF02970.16 KIY63658.1 - 1.6 9.1 5.2 0.88 9.9 2.4 2.0 2 0 0 2 2 2 0 Tubulin binding cofactor A Histone PF00125.24 KIY63659.1 - 3e-32 111.7 1.3 3.3e-32 111.6 1.3 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KIY63659.1 - 6.1e-06 26.5 0.1 7.3e-06 26.3 0.1 1.1 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KIY63659.1 - 1.7e-05 24.9 0.2 2e-05 24.7 0.2 1.0 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 KIY63659.1 - 0.00021 21.5 0.1 0.00025 21.3 0.1 1.0 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.13 KIY63659.1 - 0.025 14.6 0.1 0.031 14.3 0.1 1.2 1 0 0 1 1 1 0 Bromodomain associated TFIID-31kDa PF02291.15 KIY63659.1 - 0.032 14.3 0.1 0.033 14.3 0.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit zf-C2H2_4 PF13894.6 KIY63660.1 - 0.0011 19.7 5.5 0.32 12.0 0.1 4.3 4 0 0 4 4 4 1 C2H2-type zinc finger TF_Zn_Ribbon PF08271.12 KIY63660.1 - 0.038 13.5 0.1 0.12 11.9 0.0 1.9 2 0 0 2 2 2 0 TFIIB zinc-binding zf-H2C2_2 PF13465.6 KIY63660.1 - 0.062 13.7 0.0 0.062 13.7 0.0 3.9 6 1 0 6 6 6 0 Zinc-finger double domain zf-C2H2 PF00096.26 KIY63660.1 - 2.2 8.9 7.0 3.5 8.3 0.0 3.8 4 0 0 4 4 4 0 Zinc finger, C2H2 type Sds3 PF08598.11 KIY63661.1 - 1.9e-06 28.0 1.8 2.3e-06 27.8 1.8 1.4 1 1 0 1 1 1 1 Sds3-like zf-H2C2_2 PF13465.6 KIY63662.1 - 4.3e-08 33.2 11.7 6.2e-07 29.6 2.0 3.9 3 1 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.26 KIY63662.1 - 7.4e-05 23.0 15.1 0.00043 20.6 3.3 3.4 3 0 0 3 3 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIY63662.1 - 9.1e-05 23.0 13.6 0.0014 19.2 2.7 3.5 4 0 0 4 4 2 2 C2H2-type zinc finger zf-met PF12874.7 KIY63662.1 - 0.00034 20.9 0.3 0.00093 19.5 0.3 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KIY63662.1 - 0.01 16.1 1.3 0.45 10.9 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Zn_clus PF00172.18 KIY63662.1 - 0.011 15.8 11.1 0.011 15.8 11.1 1.7 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_9 PF16293.5 KIY63662.1 - 0.1 12.5 2.3 0.5 10.3 0.1 2.2 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) Zn_ribbon_SprT PF17283.2 KIY63662.1 - 0.19 11.7 6.0 1.2 9.2 6.0 2.3 1 1 0 1 1 1 0 SprT-like zinc ribbon domain zf-Di19 PF05605.12 KIY63662.1 - 0.22 11.9 8.1 4.1 7.8 1.1 2.5 1 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 KIY63662.1 - 0.31 11.4 6.8 0.58 10.5 0.4 2.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Zn_Tnp_IS1 PF03811.13 KIY63662.1 - 0.97 9.2 8.6 3.6 7.4 8.6 2.0 1 0 0 1 1 1 0 InsA N-terminal domain zf-C2H2_11 PF16622.5 KIY63662.1 - 1.8 8.4 10.7 0.26 11.1 1.8 3.0 3 0 0 3 3 3 0 zinc-finger C2H2-type GST_N_3 PF13417.6 KIY63663.1 - 2.6e-07 30.9 0.0 4.8e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KIY63663.1 - 2.3e-05 24.6 0.2 4.2e-05 23.8 0.2 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KIY63663.1 - 0.0034 17.4 0.6 0.01 15.9 0.1 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KIY63663.1 - 0.071 13.3 0.0 0.17 12.1 0.0 1.6 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Nucleopor_Nup85 PF07575.13 KIY63664.1 - 2.4e-60 204.7 0.0 3.8e-60 204.0 0.0 1.3 1 1 0 1 1 1 1 Nup85 Nucleoporin Lysine_decarbox PF03641.14 KIY63665.1 - 5.9e-27 94.3 0.2 3.6e-26 91.8 0.2 1.9 1 1 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 KIY63665.1 - 2.6e-06 27.1 4.9 4.7e-06 26.3 4.9 1.5 1 1 0 1 1 1 1 SLOG cluster4 family Chromo PF00385.24 KIY63666.1 - 3.1e-11 43.0 0.2 3.9e-11 42.7 0.2 1.2 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.6 KIY63666.1 - 0.0032 17.6 0.2 0.0045 17.1 0.2 1.2 1 0 0 1 1 1 1 Polycomb-like MTF2 factor 2 DUF5427 PF10310.9 KIY63667.1 - 1.2e-62 212.5 2.1 2.3e-56 191.7 0.0 2.1 1 1 1 2 2 2 2 Family of unknown function (DUF5427) Frataxin_Cyay PF01491.16 KIY63668.1 - 2.7e-39 133.6 0.0 3e-39 133.4 0.0 1.0 1 0 0 1 1 1 1 Frataxin-like domain WD40 PF00400.32 KIY63670.1 - 1.3e-18 67.0 12.9 2.8e-05 24.8 0.3 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY63670.1 - 8.1e-06 26.0 0.1 0.46 10.8 0.0 5.1 3 1 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIY63670.1 - 1.1e-05 24.6 0.0 0.00045 19.3 0.0 2.3 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KIY63670.1 - 0.00015 21.7 0.1 0.35 10.7 0.0 3.3 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 KIY63670.1 - 0.0064 15.1 0.1 0.092 11.3 0.0 2.6 4 0 0 4 4 4 1 Cytochrome D1 heme domain Bromodomain PF00439.25 KIY63671.1 - 1.8e-35 120.9 0.2 3.7e-17 62.2 0.0 3.0 3 0 0 3 3 3 2 Bromodomain BET PF17035.5 KIY63671.1 - 3.1e-16 59.3 0.2 3.1e-16 59.3 0.2 2.2 2 0 0 2 2 2 1 Bromodomain extra-terminal - transcription regulation DUF3740 PF12548.8 KIY63671.1 - 0.06 13.8 1.7 0.17 12.3 1.7 1.8 1 0 0 1 1 1 0 Sulfatase protein DUF4168 PF13767.6 KIY63671.1 - 1.4 10.2 5.4 4.8 8.4 5.4 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4168) Macoilin PF09726.9 KIY63671.1 - 8.3 4.8 6.8 18 3.7 6.8 1.4 1 0 0 1 1 1 0 Macoilin family JHY PF15261.6 KIY63671.1 - 9.6 6.9 12.4 0.16 12.7 4.2 2.3 2 0 0 2 2 2 0 Jhy protein G-patch PF01585.23 KIY63672.1 - 6.5e-09 35.5 0.3 2.5e-08 33.7 0.0 2.1 2 0 0 2 2 2 1 G-patch domain zf-C2H2_jaz PF12171.8 KIY63672.1 - 9.3e-07 29.0 5.9 1.6e-06 28.2 5.9 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KIY63672.1 - 1.4e-05 25.3 1.3 2.4e-05 24.5 1.3 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type G-patch_2 PF12656.7 KIY63672.1 - 0.00056 19.9 0.0 0.00056 19.9 0.0 2.8 3 0 0 3 3 3 1 G-patch domain zf-C2H2_2 PF12756.7 KIY63672.1 - 0.0047 17.2 0.2 0.0079 16.5 0.2 1.3 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) Rotamase_2 PF13145.6 KIY63672.1 - 0.0058 17.5 1.3 0.014 16.2 1.3 1.6 1 0 0 1 1 1 1 PPIC-type PPIASE domain zf-C2H2_aberr PF17017.5 KIY63672.1 - 0.019 15.1 0.6 0.032 14.4 0.6 1.3 1 0 0 1 1 1 0 Aberrant zinc-finger DUF2854 PF11016.8 KIY63672.1 - 0.22 11.4 0.4 0.37 10.7 0.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2854) SAE2 PF08573.10 KIY63672.1 - 5.1 8.3 11.4 2.8 9.1 5.2 2.5 1 1 1 2 2 2 0 DNA repair protein endonuclease SAE2/CtIP C-terminus Proteasome PF00227.26 KIY63673.1 - 3.4e-36 124.5 0.0 3.9e-36 124.3 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Trans_coact PF16805.5 KIY63673.1 - 0.1 12.7 0.1 0.67 10.1 0.0 2.2 3 0 0 3 3 3 0 Phage late-transcription coactivator Rhodanese PF00581.20 KIY63674.1 - 8e-14 52.1 0.0 9.8e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain Imm8 PF15586.6 KIY63677.1 - 0.073 13.1 0.0 0.1 12.6 0.0 1.2 1 0 0 1 1 1 0 Immunity protein 8 Rhodanese PF00581.20 KIY63678.1 - 2.9e-16 59.9 0.0 5.6e-10 39.7 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain V-ATPase_C PF03223.15 KIY63679.1 - 2.6e-129 431.8 8.0 3e-129 431.7 8.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit C KH_1 PF00013.29 KIY63680.1 - 2.7e-36 123.2 0.1 1.5e-08 34.4 0.0 7.1 7 0 0 7 7 7 6 KH domain RWD PF05773.22 KIY63681.1 - 9.9e-16 58.1 0.3 2.5e-15 56.8 0.3 1.6 1 0 0 1 1 1 1 RWD domain IBR PF01485.21 KIY63681.1 - 1.7e-15 57.0 20.9 3.9e-10 39.8 5.3 3.9 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 KIY63681.1 - 0.0043 17.3 9.9 0.0043 17.3 9.9 4.6 4 1 1 5 5 5 2 Ring finger domain FYVE_2 PF02318.16 KIY63681.1 - 0.012 15.8 4.7 0.012 15.8 4.7 3.4 1 1 2 4 4 4 0 FYVE-type zinc finger zf-piccolo PF05715.13 KIY63681.1 - 0.02 15.0 8.6 0.02 15.0 8.6 3.1 3 0 0 3 3 3 0 Piccolo Zn-finger Urb2 PF10441.9 KIY63682.1 - 3e-44 151.4 1.1 1.5e-43 149.2 0.1 2.7 2 0 0 2 2 2 1 Urb2/Npa2 family DUF2670 PF10875.8 KIY63683.1 - 0.0055 16.8 4.4 0.013 15.7 4.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2670) DUF1772 PF08592.11 KIY63683.1 - 0.73 10.1 7.9 0.6 10.4 1.6 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1772) C2 PF00168.30 KIY63684.1 - 1.9e-25 89.1 0.0 3.1e-14 53.1 0.0 3.0 3 0 0 3 3 3 2 C2 domain MMM1 PF10296.9 KIY63684.1 - 0.096 11.7 0.0 0.18 10.8 0.0 1.4 1 0 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 p450 PF00067.22 KIY63685.1 - 3.4e-76 256.9 0.0 4.6e-76 256.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 F-box PF00646.33 KIY63686.1 - 0.0015 18.4 0.0 0.0042 16.9 0.0 1.8 1 0 0 1 1 1 1 F-box domain F-box PF00646.33 KIY63687.1 - 0.09 12.7 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 F-box domain zf-C2H2 PF00096.26 KIY63688.1 - 1.8e-12 46.9 9.8 2.7e-06 27.5 1.7 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIY63688.1 - 4.3e-09 36.4 8.3 0.00058 20.5 0.9 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KIY63688.1 - 2.5e-08 34.0 11.0 1.3e-06 28.5 3.7 3.1 3 0 0 3 3 3 1 Zinc-finger double domain CHORD PF04968.12 KIY63688.1 - 0.0018 19.0 3.0 0.5 11.1 0.2 2.1 1 1 1 2 2 2 2 CHORD zf-C2H2_aberr PF17017.5 KIY63688.1 - 0.0055 16.9 2.2 0.0069 16.6 2.2 1.2 1 0 0 1 1 1 1 Aberrant zinc-finger zf-TRAF PF02176.18 KIY63688.1 - 0.0062 17.2 4.4 0.014 16.0 4.4 1.6 1 1 0 1 1 1 1 TRAF-type zinc finger FOXP-CC PF16159.5 KIY63688.1 - 0.0093 16.6 0.8 1.5 9.5 0.1 2.0 1 1 1 2 2 2 1 FOXP coiled-coil domain zf-BED PF02892.15 KIY63688.1 - 0.016 15.2 6.4 0.67 10.0 0.9 2.2 1 1 1 2 2 2 0 BED zinc finger zf-met PF12874.7 KIY63688.1 - 0.03 14.7 0.1 2.4 8.6 0.0 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KIY63688.1 - 0.034 14.5 2.2 4.5 7.7 0.1 3.0 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-LYAR PF08790.11 KIY63688.1 - 0.045 13.7 0.8 8.9 6.3 0.1 2.3 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-H2C2_5 PF13909.6 KIY63688.1 - 0.25 11.1 14.7 0.32 10.8 0.2 3.3 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 KIY63688.1 - 2.5 8.2 11.7 3.4 7.8 1.5 3.0 2 2 0 2 2 2 0 C2H2-type zinc finger Fungal_trans PF04082.18 KIY63689.1 - 2.8e-24 85.6 0.1 6.2e-24 84.5 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY63689.1 - 1.8e-07 31.2 12.5 3.5e-07 30.2 12.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2121 PF09894.9 KIY63689.1 - 0.029 13.9 0.0 0.047 13.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2121) F-box PF00646.33 KIY63690.1 - 0.00027 20.7 0.3 0.00078 19.3 0.3 1.7 1 0 0 1 1 1 1 F-box domain SSP160 PF06933.11 KIY63690.1 - 0.56 8.3 3.6 0.74 7.9 3.6 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 YL1 PF05764.13 KIY63691.1 - 0.016 15.3 4.7 0.02 15.0 4.7 1.2 1 0 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.14 KIY63691.1 - 2.4 6.3 6.9 2.8 6.1 6.9 1.1 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 KIY63691.1 - 4.7 6.4 10.0 5.9 6.1 10.0 1.1 1 0 0 1 1 1 0 NOA36 protein NACHT PF05729.12 KIY63692.1 - 6.1e-08 32.8 0.0 1.9e-07 31.2 0.0 1.9 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KIY63692.1 - 4.5e-06 27.2 0.6 1.1e-05 25.8 0.1 1.9 2 0 0 2 2 2 1 AAA ATPase domain APS_kinase PF01583.20 KIY63692.1 - 0.015 15.2 0.1 0.031 14.2 0.1 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA PF00004.29 KIY63692.1 - 0.071 13.5 0.0 0.19 12.1 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KIY63692.1 - 0.17 11.0 0.0 0.38 9.9 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain WD40 PF00400.32 KIY63692.1 - 0.26 12.2 5.2 2.4 9.1 0.2 3.3 3 0 0 3 3 3 0 WD domain, G-beta repeat Ras PF00071.22 KIY63693.1 - 2e-53 180.3 0.0 2.3e-53 180.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIY63693.1 - 1.3e-29 102.8 0.0 2.4e-29 102.0 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIY63693.1 - 3.1e-13 49.5 0.0 4e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KIY63693.1 - 4.6e-06 26.7 0.0 7.9e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KIY63693.1 - 5.1e-05 22.8 0.0 6.5e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KIY63693.1 - 0.0026 17.3 0.2 0.012 15.2 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KIY63693.1 - 0.0058 16.6 0.3 0.62 9.9 0.1 2.7 1 1 1 3 3 3 1 RsgA GTPase AAA_16 PF13191.6 KIY63693.1 - 0.023 15.1 0.0 0.034 14.5 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain TniB PF05621.11 KIY63693.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein SRPRB PF09439.10 KIY63693.1 - 0.19 11.1 0.0 0.44 9.9 0.0 1.5 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KIY63693.1 - 0.37 9.9 0.6 3.1 6.9 0.2 2.0 1 1 1 2 2 2 0 G-protein alpha subunit Fucose_iso_C PF02952.17 KIY63695.1 - 0.037 13.7 0.0 0.042 13.6 0.0 1.2 1 0 0 1 1 1 0 L-fucose isomerase, C-terminal domain ChAPs PF09295.10 KIY63697.1 - 2e-144 481.4 0.0 4.7e-143 477.0 0.0 2.0 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_19 PF14559.6 KIY63697.1 - 1.1e-08 35.4 0.1 0.0013 19.2 0.0 4.2 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_15 PF13429.6 KIY63697.1 - 3.8e-05 23.1 4.3 0.11 11.7 0.3 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KIY63697.1 - 0.00058 19.9 1.0 2.7 8.4 0.0 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 KIY63697.1 - 0.00075 19.4 1.0 9.9 6.6 0.1 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 KIY63697.1 - 0.0091 16.3 0.0 6.4 7.4 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KIY63697.1 - 0.027 15.3 2.8 21 6.3 0.0 5.5 3 2 1 5 5 5 0 Tetratricopeptide repeat TPR_21 PF09976.9 KIY63697.1 - 0.049 13.3 0.0 3.2 7.4 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat-like domain TPR_1 PF00515.28 KIY63697.1 - 0.32 10.9 2.7 54 3.9 0.2 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Zn_clus PF00172.18 KIY63698.1 - 4.1e-06 26.8 8.6 8.4e-06 25.8 8.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Exo_endo_phos PF03372.23 KIY63699.1 - 4.3e-07 29.7 5.3 7.3e-07 28.9 5.3 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family TMCCDC2 PF15844.5 KIY63701.1 - 1.1 9.2 5.2 0.19 11.7 0.6 1.9 2 0 0 2 2 2 0 Transmembrane and coiled-coil domain-containing protein 2 DUF2569 PF10754.9 KIY63701.1 - 2.3 8.7 23.6 1.6 9.2 5.9 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF2569) DUF3278 PF11683.8 KIY63701.1 - 2.4 8.2 6.9 0.99 9.5 1.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3278) RTA1 PF04479.13 KIY63703.1 - 2.1e-55 187.6 2.3 3e-55 187.1 2.3 1.2 1 0 0 1 1 1 1 RTA1 like protein DUF1772 PF08592.11 KIY63704.1 - 0.071 13.4 7.5 2.2 8.6 0.1 2.8 1 1 0 2 2 2 0 Domain of unknown function (DUF1772) SdpI PF13630.6 KIY63704.1 - 0.66 10.2 0.0 0.66 10.2 0.0 2.8 2 1 1 3 3 3 0 SdpI/YhfL protein family DUF1129 PF06570.11 KIY63704.1 - 0.71 9.3 3.2 1.1 8.7 1.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) PhoLip_ATPase_C PF16212.5 KIY63704.1 - 1.5 8.5 13.0 7.9 6.1 12.7 2.0 1 1 0 1 1 1 0 Phospholipid-translocating P-type ATPase C-terminal Cytochrom_B_C PF00032.17 KIY63704.1 - 1.7 9.0 5.7 0.49 10.7 0.8 2.5 2 1 1 3 3 3 0 Cytochrome b(C-terminal)/b6/petD Y_phosphatase3 PF13350.6 KIY63706.1 - 1.9e-62 211.3 0.0 2.2e-62 211.1 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 KIY63706.1 - 0.00019 21.1 0.0 0.00027 20.6 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 KIY63706.1 - 0.00045 19.9 0.0 0.00066 19.3 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KIY63706.1 - 0.18 11.6 0.0 0.38 10.6 0.0 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 KIY63706.1 - 0.19 11.8 0.1 0.99 9.5 0.0 2.1 2 0 0 2 2 2 0 Inositol hexakisphosphate Myotub-related PF06602.14 KIY63706.1 - 0.2 10.6 0.0 0.27 10.1 0.0 1.1 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain MotA_ExbB PF01618.16 KIY63707.1 - 0.015 15.1 0.0 0.018 14.8 0.0 1.2 1 0 0 1 1 1 0 MotA/TolQ/ExbB proton channel family Abhydrolase_6 PF12697.7 KIY63708.1 - 2.6e-26 93.6 0.8 4.5e-26 92.8 0.8 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIY63708.1 - 3.7e-07 29.7 0.2 5.7e-07 29.0 0.2 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KIY63708.1 - 0.00013 21.7 0.1 0.0016 18.1 0.1 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Thioesterase PF00975.20 KIY63708.1 - 0.056 13.5 0.1 0.16 12.1 0.1 1.7 2 1 0 2 2 2 0 Thioesterase domain PGAP1 PF07819.13 KIY63708.1 - 0.071 12.8 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Pro_isomerase PF00160.21 KIY63709.1 - 3e-46 157.6 0.1 3.3e-46 157.4 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SNARE_assoc PF09335.11 KIY63711.1 - 2.1e-15 57.3 7.4 2.1e-15 57.3 7.4 2.5 2 1 0 2 2 2 1 SNARE associated Golgi protein DUF4501 PF14946.6 KIY63711.1 - 0.055 13.6 0.1 0.14 12.3 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4501) Big_4 PF07532.11 KIY63711.1 - 0.073 12.8 0.0 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 4) Wzy_C_2 PF11846.8 KIY63711.1 - 0.14 12.1 0.0 0.14 12.1 0.0 2.1 2 0 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal Amino_oxidase PF01593.24 KIY63712.1 - 0.021 14.1 0.0 0.037 13.3 0.0 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase POT1 PF02765.17 KIY63713.1 - 0.049 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Telomeric single stranded DNA binding POT1/CDC13 P19Arf_N PF07392.12 KIY63713.1 - 0.18 12.3 2.1 1 9.8 0.5 2.6 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor 2a p19Arf N-terminus F-box-like PF12937.7 KIY63714.1 - 5.5e-07 29.4 1.0 7.3e-06 25.8 0.1 2.6 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 KIY63716.1 - 3.4e-10 39.6 0.2 5.9e-10 38.9 0.2 1.4 1 0 0 1 1 1 1 F-box-like Dynamitin PF04912.14 KIY63716.1 - 0.038 13.3 0.3 0.047 13.0 0.3 1.1 1 0 0 1 1 1 0 Dynamitin Prefoldin_2 PF01920.20 KIY63716.1 - 0.053 13.5 0.6 0.076 13.0 0.6 1.2 1 0 0 1 1 1 0 Prefoldin subunit EnY2 PF10163.9 KIY63718.1 - 0.02 15.2 0.0 0.044 14.2 0.0 1.5 1 0 0 1 1 1 0 Transcription factor e(y)2 PP2C PF00481.21 KIY63719.1 - 1.9e-37 129.3 0.0 7.9e-37 127.3 0.0 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KIY63719.1 - 0.035 13.7 0.1 0.061 12.9 0.1 1.4 1 0 0 1 1 1 0 Protein phosphatase 2C Pro_isomerase PF00160.21 KIY63720.1 - 3.9e-43 147.4 0.0 5.9e-43 146.9 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD U-box PF04564.15 KIY63720.1 - 0.0087 16.2 0.0 0.019 15.1 0.0 1.5 1 0 0 1 1 1 1 U-box domain Rtf2 PF04641.12 KIY63720.1 - 0.028 13.8 0.0 2.1 7.6 0.0 2.2 2 0 0 2 2 2 0 Rtf2 RING-finger zf-NOSIP PF15906.5 KIY63720.1 - 0.033 14.3 0.0 0.083 13.0 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein zf-Nse PF11789.8 KIY63720.1 - 0.11 12.4 0.1 2.3 8.1 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Ribosomal_60s PF00428.19 KIY63720.1 - 0.39 11.3 13.4 0.12 13.0 3.3 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein zf-SCNM1 PF15803.5 KIY63721.1 - 0.00013 21.5 0.9 0.00025 20.6 0.9 1.5 1 1 0 1 1 1 1 Zinc-finger of sodium channel modifier 1 DUF2313 PF10076.9 KIY63722.1 - 0.0075 16.1 0.0 1 9.2 0.0 2.5 2 0 0 2 2 2 2 Uncharacterised protein conserved in bacteria (DUF2313) Unstab_antitox PF09720.10 KIY63723.1 - 0.46 10.6 1.9 1.4 9.1 0.5 2.4 2 0 0 2 2 2 0 Putative addiction module component PIN_2 PF10130.9 KIY63724.1 - 0.066 13.4 0.5 0.78 10.0 0.1 2.7 2 1 1 3 3 3 0 PIN domain TPD52 PF04201.15 KIY63726.1 - 0.03 13.9 0.1 0.068 12.8 0.1 1.5 1 0 0 1 1 1 0 Tumour protein D52 family RNA_pol_inhib PF16857.5 KIY63726.1 - 0.058 13.2 0.0 1 9.2 0.0 2.7 3 0 0 3 3 3 0 RNA polymerase inhibitor MFS_1 PF07690.16 KIY63727.1 - 2.1e-28 99.3 31.3 3.1e-28 98.7 29.4 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily UreD PF01774.17 KIY63728.1 - 9.1e-67 225.1 0.1 1.1e-66 224.9 0.1 1.0 1 0 0 1 1 1 1 UreD urease accessory protein RNA_pol_L_2 PF13656.6 KIY63731.1 - 5.1e-26 90.2 0.0 6.8e-26 89.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 KIY63731.1 - 1.6e-10 40.3 0.0 2.3e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Ribosomal_L27A PF00828.19 KIY63732.1 - 1e-20 74.7 0.0 1.5e-20 74.2 0.0 1.3 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A A_deaminase PF00962.22 KIY63733.1 - 5.2e-20 72.0 0.0 7.9e-20 71.4 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase MFS_1 PF07690.16 KIY63734.1 - 4e-30 104.9 21.9 5.8e-30 104.4 21.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TMEM191C PF15194.6 KIY63734.1 - 0.094 12.9 1.4 0.72 10.0 0.1 2.2 2 0 0 2 2 2 0 TMEM191C family Nup192 PF11894.8 KIY63736.1 - 1.6e-203 678.7 0.0 2e-203 678.4 0.0 1.0 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 Amidohydro_3 PF07969.11 KIY63737.1 - 0.0032 17.0 0.0 2.3 7.6 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family zf-HC3 PF16827.5 KIY63737.1 - 0.0056 16.9 1.2 4.5 7.6 0.1 3.4 3 0 0 3 3 3 1 zinc-finger DUF3379 PF11859.8 KIY63737.1 - 0.12 11.6 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3379) ORC6 PF05460.13 KIY63738.1 - 0.086 12.1 9.1 0.15 11.3 9.1 1.4 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) BIR PF00653.21 KIY63738.1 - 2.1 9.1 9.3 18 6.1 7.6 2.5 2 0 0 2 2 2 0 Inhibitor of Apoptosis domain IHABP4_N PF16174.5 KIY63738.1 - 9.6 6.8 14.9 3.8 8.1 12.3 1.6 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal HSP70 PF00012.20 KIY63740.1 - 2.2e-261 868.3 9.9 2.4e-261 868.2 9.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KIY63740.1 - 1.2e-19 70.4 1.0 9.8e-19 67.3 0.5 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FIVAR PF07554.13 KIY63740.1 - 0.004 17.9 1.5 0.39 11.5 0.1 3.0 3 0 0 3 3 3 1 FIVAR domain DDR PF08841.10 KIY63740.1 - 0.025 13.6 1.0 0.28 10.1 0.5 2.2 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.18 KIY63740.1 - 0.032 13.5 0.2 0.032 13.5 0.2 2.5 4 0 0 4 4 4 0 Hydantoinase/oxoprolinase RGS12_us2 PF16611.5 KIY63740.1 - 0.089 13.2 0.4 0.3 11.5 0.4 1.8 1 0 0 1 1 1 0 Unstructured region between RBD and GoLoco Spectrin PF00435.21 KIY63740.1 - 0.24 11.9 8.4 3 8.4 0.3 3.3 3 0 0 3 3 3 0 Spectrin repeat betaPIX_CC PF16523.5 KIY63740.1 - 0.51 10.2 2.9 9.1 6.2 0.1 2.6 2 0 0 2 2 2 0 betaPIX coiled coil Noc2 PF03715.13 KIY63741.1 - 7.4e-75 252.0 0.0 1.2e-74 251.3 0.0 1.3 1 0 0 1 1 1 1 Noc2p family RNA_pol_Rpb2_1 PF04563.15 KIY63742.1 - 5.5e-29 101.1 0.0 6.7e-29 100.9 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase beta subunit Hepatitis_core PF00906.20 KIY63744.1 - 0.78 9.3 4.6 0.89 9.1 4.6 1.1 1 0 0 1 1 1 0 Hepatitis core antigen DUF1640 PF07798.11 KIY63745.1 - 0.054 13.5 1.9 0.087 12.9 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) RR_TM4-6 PF06459.12 KIY63745.1 - 0.46 10.3 6.6 0.87 9.4 6.6 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TBK1_ULD PF18396.1 KIY63748.1 - 0.14 12.1 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain PGAP1 PF07819.13 KIY63750.1 - 2.8e-06 27.2 0.1 7e-06 25.9 0.1 1.6 1 1 0 1 1 1 1 PGAP1-like protein Palm_thioest PF02089.15 KIY63750.1 - 0.00016 21.6 0.0 0.00022 21.1 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF676 PF05057.14 KIY63750.1 - 0.00099 18.7 0.1 0.0048 16.4 0.0 1.9 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 KIY63750.1 - 0.0015 19.2 0.2 0.0015 19.2 0.2 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KIY63750.1 - 0.0031 17.2 1.4 0.033 13.8 0.2 2.6 2 1 0 2 2 2 1 alpha/beta hydrolase fold DUF915 PF06028.11 KIY63750.1 - 0.02 14.2 0.0 0.061 12.6 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Hydrolase_4 PF12146.8 KIY63750.1 - 0.11 11.7 0.0 0.26 10.5 0.0 1.6 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Thioesterase PF00975.20 KIY63750.1 - 0.12 12.5 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain LCAT PF02450.15 KIY63750.1 - 0.19 10.8 0.0 0.31 10.2 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Vps62 PF06101.11 KIY63751.1 - 3.5e-12 45.4 2.3 1.1e-11 43.8 1.2 1.9 2 0 0 2 2 2 2 Vacuolar protein sorting-associated protein 62 Pkinase PF00069.25 KIY63752.1 - 2e-54 184.7 0.0 2.6e-54 184.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY63752.1 - 3.1e-31 108.6 0.0 4.2e-31 108.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 KIY63752.1 - 2.2e-10 40.7 0.1 4.4e-10 39.8 0.1 1.5 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.6 KIY63752.1 - 3.1e-06 26.7 0.0 4.6e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KIY63752.1 - 3e-05 23.5 0.0 6e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Yop-YscD_cpl PF16697.5 KIY63752.1 - 0.00024 21.3 0.0 0.00072 19.8 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Haspin_kinase PF12330.8 KIY63752.1 - 0.076 11.9 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain MMR_HSR1 PF01926.23 KIY63753.1 - 1.5e-15 57.3 0.0 1.3e-14 54.3 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIY63753.1 - 1.3e-07 31.7 0.0 0.0002 21.3 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 KIY63753.1 - 1.6e-05 24.5 0.1 9.2e-05 22.0 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B AIG1 PF04548.16 KIY63753.1 - 0.00066 19.1 0.1 0.0014 18.0 0.1 1.5 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 KIY63753.1 - 0.021 14.9 0.0 0.071 13.2 0.0 1.9 1 0 0 1 1 1 0 Dynamin family Astro_capsid_p PF12226.8 KIY63753.1 - 1.3 8.1 11.9 2.1 7.4 11.9 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein RNA_pol_3_Rpc31 PF11705.8 KIY63753.1 - 4.3 7.5 17.0 0.21 11.8 11.0 1.9 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 DNA_pol_phi PF04931.13 KIY63753.1 - 5.7 4.9 15.0 8 4.4 15.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi Complex1_LYR PF05347.15 KIY63754.1 - 0.014 15.4 1.2 0.043 13.9 1.2 1.8 1 0 0 1 1 1 0 Complex 1 protein (LYR family) SNF2_N PF00176.23 KIY63755.1 - 3.5e-56 190.4 0.4 5.3e-56 189.8 0.4 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KIY63755.1 - 2.7e-18 66.3 0.0 5.6e-18 65.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 KIY63755.1 - 3.1e-18 66.0 1.3 2.1e-16 60.0 0.3 2.6 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 Chromo PF00385.24 KIY63755.1 - 5.1e-07 29.5 2.9 0.0016 18.3 0.1 3.2 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.15 KIY63755.1 - 5.7e-07 29.7 0.0 1.6e-06 28.2 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-PHD-like PF15446.6 KIY63755.1 - 1.1e-05 25.1 7.6 0.001 18.7 1.1 3.3 2 1 0 2 2 2 2 PHD/FYVE-zinc-finger like domain PHD_4 PF16866.5 KIY63755.1 - 0.0024 17.9 2.9 0.027 14.6 0.6 3.3 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 KIY63755.1 - 0.044 13.7 0.1 0.044 13.7 0.1 3.8 5 0 0 5 5 4 0 PHD-finger Zf_RING PF16744.5 KIY63755.1 - 0.052 13.7 1.6 0.12 12.5 0.2 2.2 2 0 0 2 2 2 0 KIAA1045 RING finger SRP54 PF00448.22 KIY63755.1 - 0.14 11.7 0.1 0.35 10.5 0.1 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain C1_1 PF00130.22 KIY63755.1 - 0.33 10.9 6.0 1.8 8.5 0.2 3.3 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_9 PF13901.6 KIY63755.1 - 0.77 9.7 3.4 7.2 6.5 1.0 2.7 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon Lar_restr_allev PF14354.6 KIY63755.1 - 7.9 6.9 12.1 22 5.5 0.4 4.6 3 2 0 3 3 3 0 Restriction alleviation protein Lar Glyco_hydro_88 PF07470.13 KIY63756.1 - 1.1e-15 57.5 0.2 1.6e-15 57.1 0.2 1.3 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 F-box PF00646.33 KIY63757.1 - 2.2e-07 30.6 0.1 5.2e-07 29.4 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KIY63757.1 - 0.00027 20.8 0.1 0.00059 19.7 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KIY63757.1 - 0.022 14.6 0.0 0.056 13.3 0.0 1.6 1 0 0 1 1 1 0 F-box HBB PF06777.11 KIY63757.1 - 0.21 11.3 0.0 4.5 6.9 0.0 2.5 3 0 0 3 3 3 0 Helical and beta-bridge domain F-box PF00646.33 KIY63758.1 - 4.8e-08 32.7 1.4 1.4e-07 31.2 1.4 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KIY63758.1 - 0.0001 22.1 0.3 0.00024 20.9 0.3 1.6 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KIY63758.1 - 0.068 13.1 0.2 0.19 11.6 0.2 1.8 1 0 0 1 1 1 0 F-box F-box-like PF12937.7 KIY63760.1 - 0.00086 19.2 0.3 0.007 16.2 0.0 2.6 2 1 0 2 2 2 1 F-box-like TFIIA PF03153.13 KIY63761.1 - 2.6 7.9 26.7 4.7 7.1 26.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit IR1-M PF12185.8 KIY63763.1 - 0.089 12.7 0.0 19 5.3 0.0 2.8 2 0 0 2 2 2 0 Nup358/RanBP2 E3 ligase domain Sporozoite_P67 PF05642.11 KIY63766.1 - 1.1 7.2 6.7 1.5 6.8 6.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Plavaka PF18759.1 KIY63769.1 - 1.8e-111 372.5 0.2 2.8e-111 371.9 0.2 1.3 1 0 0 1 1 1 1 Plavaka transposase zf-C2H2 PF00096.26 KIY63769.1 - 0.039 14.4 0.2 0.039 14.4 0.2 2.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_8 PF15909.5 KIY63769.1 - 0.13 12.6 0.4 0.51 10.7 0.1 2.2 2 0 0 2 2 2 0 C2H2-type zinc ribbon SDA1 PF05285.12 KIY63769.1 - 1.8 7.9 12.2 3.4 7.0 12.2 1.4 1 0 0 1 1 1 0 SDA1 IBR PF01485.21 KIY63771.1 - 2.3e-06 27.8 5.3 2.3e-06 27.8 5.3 2.4 2 1 0 2 2 2 1 IBR domain, a half RING-finger domain zinc_ribbon_9 PF14369.6 KIY63771.1 - 3.3 8.0 8.6 54 4.2 0.0 4.3 4 0 0 4 4 4 0 zinc-ribbon Tenui_NS3 PF05310.12 KIY63772.1 - 0.086 12.9 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Tenuivirus movement protein Aldedh PF00171.22 KIY63773.1 - 1.3e-79 267.9 0.0 1.7e-79 267.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DELLA PF12041.8 KIY63773.1 - 0.17 11.8 0.1 1.3 8.9 0.0 2.3 2 0 0 2 2 2 0 Transcriptional regulator DELLA protein N terminal MAM33 PF02330.16 KIY63774.1 - 2.5e-60 204.1 0.1 2.9e-60 203.9 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial glycoprotein DDE_3 PF13358.6 KIY63775.1 - 1.8e-08 34.3 0.1 0.003 17.3 0.0 3.5 3 0 0 3 3 3 3 DDE superfamily endonuclease Thioredoxin_8 PF13905.6 KIY63776.1 - 0.12 12.7 0.0 2.1 8.7 0.1 2.1 2 0 0 2 2 2 0 Thioredoxin-like AIP3 PF03915.13 KIY63778.1 - 4.1e-140 467.5 4.2 4.1e-140 467.5 4.2 1.7 2 0 0 2 2 2 1 Actin interacting protein 3 Sec20 PF03908.13 KIY63778.1 - 0.034 14.0 4.1 0.26 11.2 0.3 3.3 3 1 0 3 3 3 0 Sec20 Lectin_N PF03954.14 KIY63778.1 - 0.11 12.3 6.3 0.033 13.9 0.9 2.8 3 0 0 3 3 3 0 Hepatic lectin, N-terminal domain DUF1319 PF07028.11 KIY63778.1 - 1.9 8.7 5.5 63 3.8 2.1 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF1319) NPV_P10 PF05531.12 KIY63778.1 - 2.4 8.7 12.1 1.8 9.1 0.7 4.6 4 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein FliT PF05400.13 KIY63778.1 - 8.6 7.3 9.9 3.5 8.5 0.2 3.7 3 0 0 3 3 3 0 Flagellar protein FliT ApoLp-III PF07464.11 KIY63778.1 - 9.1 6.4 13.9 13 5.8 5.2 4.4 3 1 1 4 4 4 0 Apolipophorin-III precursor (apoLp-III) Syntaxin-6_N PF09177.11 KIY63778.1 - 9.7 6.8 16.5 8.8 7.0 1.9 4.8 4 1 1 5 5 5 0 Syntaxin 6, N-terminal Cellulase PF00150.18 KIY63779.1 - 1.6e-15 57.3 1.3 2.9e-15 56.4 1.3 1.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) ACC_central PF08326.12 KIY63781.1 - 3.9e-240 799.0 0.0 5.2e-240 798.6 0.0 1.2 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 KIY63781.1 - 2.7e-169 564.0 0.0 3.6e-169 563.5 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 KIY63781.1 - 4.1e-54 183.3 0.1 9.4e-53 178.8 0.0 2.5 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KIY63781.1 - 3.2e-30 104.9 0.0 9.7e-30 103.4 0.0 1.9 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KIY63781.1 - 6.5e-21 74.5 0.0 1.7e-19 69.9 0.0 3.2 4 0 0 4 4 4 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 KIY63781.1 - 1.3e-15 57.0 0.0 2.7e-15 55.9 0.0 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_3 PF02655.14 KIY63781.1 - 0.0011 19.0 0.0 0.003 17.6 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.22 KIY63781.1 - 0.032 13.8 0.0 0.078 12.5 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain ATPgrasp_Ter PF15632.6 KIY63781.1 - 0.096 12.4 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon DUF5127 PF17168.4 KIY63782.1 - 3.2e-61 207.0 1.1 3.2e-61 207.0 1.1 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 KIY63782.1 - 1.2e-36 125.9 0.0 2.3e-36 125.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 KIY63782.1 - 3.8e-33 115.3 1.7 6.9e-33 114.4 1.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) Bac_rhamnosid6H PF17389.2 KIY63782.1 - 0.00017 21.0 0.3 0.0055 16.0 0.3 2.3 1 1 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Adeno_E3_CR2 PF02439.15 KIY63782.1 - 0.00078 19.2 0.2 0.0018 18.0 0.2 1.5 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Syndecan PF01034.20 KIY63782.1 - 0.04 13.8 0.1 0.08 12.9 0.1 1.5 1 0 0 1 1 1 0 Syndecan domain Dynein_light PF01221.18 KIY63783.1 - 7.1e-40 135.2 1.1 8.2e-40 135.0 1.1 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 ATP-synt_C PF00137.21 KIY63784.1 - 2.3e-33 114.3 35.5 6.3e-22 77.7 15.1 2.3 2 0 0 2 2 2 2 ATP synthase subunit C SH PF01445.17 KIY63784.1 - 0.46 10.5 4.4 0.24 11.4 0.4 2.1 2 0 0 2 2 2 0 Viral small hydrophobic protein DUF2970 PF11174.8 KIY63784.1 - 0.82 9.6 7.7 0.33 10.8 0.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) FAD_binding_4 PF01565.23 KIY63785.1 - 8.2e-22 77.4 7.1 2.4e-21 75.9 7.1 1.8 1 1 0 1 1 1 1 FAD binding domain BBE PF08031.12 KIY63785.1 - 1.5e-12 47.4 0.4 3e-12 46.4 0.4 1.5 1 0 0 1 1 1 1 Berberine and berberine like zf-MYND PF01753.18 KIY63786.1 - 6.5e-05 22.9 12.9 0.00012 22.1 12.9 1.4 1 0 0 1 1 1 1 MYND finger Glyco_hydro_35 PF01301.19 KIY63787.1 - 7.9e-76 255.7 0.1 1.2e-75 255.1 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 KIY63787.1 - 7.3e-62 207.0 1.2 1.9e-34 118.6 0.0 2.7 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.9 KIY63787.1 - 1.6e-33 116.0 0.1 2.7e-33 115.3 0.1 1.3 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.6 KIY63787.1 - 1.6e-18 66.0 0.1 3.7e-18 64.9 0.1 1.6 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Amidohydro_2 PF04909.14 KIY63787.1 - 0.044 13.6 0.0 0.093 12.5 0.0 1.5 1 0 0 1 1 1 0 Amidohydrolase CBM-like PF14683.6 KIY63787.1 - 0.098 12.5 0.0 0.64 9.9 0.0 2.2 2 0 0 2 2 2 0 Polysaccharide lyase family 4, domain III Glyco_hydro_42 PF02449.15 KIY63787.1 - 0.11 11.8 0.1 1 8.6 0.1 2.0 1 1 0 1 1 1 0 Beta-galactosidase DcpS_C PF11969.8 KIY63788.1 - 3.2e-25 88.8 0.0 4.6e-25 88.3 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.12 KIY63788.1 - 2.9e-20 73.0 0.0 4.5e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal bZIP_2 PF07716.15 KIY63791.1 - 0.00015 21.8 9.9 0.00021 21.3 9.9 1.2 1 0 0 1 1 1 1 Basic region leucine zipper PspA_IM30 PF04012.12 KIY63791.1 - 0.00048 19.8 3.6 0.00059 19.5 3.6 1.1 1 0 0 1 1 1 1 PspA/IM30 family bZIP_1 PF00170.21 KIY63791.1 - 0.00058 19.9 9.3 0.00079 19.5 9.3 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 KIY63791.1 - 0.0042 17.6 6.9 0.0053 17.2 6.9 1.1 1 0 0 1 1 1 1 bZIP Maf transcription factor Cep57_CLD_2 PF14197.6 KIY63791.1 - 0.0062 16.6 1.5 0.0062 16.6 1.5 1.8 1 1 1 2 2 2 1 Centrosome localisation domain of PPC89 SR-25 PF10500.9 KIY63791.1 - 0.0063 16.1 1.2 0.0074 15.9 1.2 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein IMUP PF15761.5 KIY63791.1 - 0.01 16.5 0.8 0.013 16.2 0.8 1.2 1 0 0 1 1 1 0 Immortalisation up-regulated protein DUF4618 PF15397.6 KIY63791.1 - 0.019 14.4 1.4 0.023 14.1 1.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) TPR_MLP1_2 PF07926.12 KIY63791.1 - 0.049 13.7 6.8 0.066 13.3 6.8 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein TMCO5 PF14992.6 KIY63791.1 - 0.11 12.1 2.0 0.13 11.8 2.0 1.0 1 0 0 1 1 1 0 TMCO5 family DUF4407 PF14362.6 KIY63791.1 - 0.11 11.8 1.9 0.13 11.6 1.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Prominin PF05478.11 KIY63791.1 - 0.29 9.1 0.4 0.33 8.9 0.4 1.0 1 0 0 1 1 1 0 Prominin CCDC106 PF15794.5 KIY63791.1 - 2.5 7.7 11.1 1.1 8.9 1.4 2.0 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 106 DivIC PF04977.15 KIY63791.1 - 4.6 7.1 8.0 82 3.1 8.0 2.1 1 1 0 1 1 1 0 Septum formation initiator DUF3274 PF11678.8 KIY63792.1 - 0.093 12.0 0.0 0.099 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3274) Fungal_trans PF04082.18 KIY63793.1 - 2.2e-31 108.9 0.0 3.3e-31 108.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY63793.1 - 9.2e-07 28.9 8.0 1.5e-06 28.2 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugarporin_N PF11471.8 KIY63793.1 - 0.43 10.6 1.9 0.97 9.4 1.9 1.5 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Fungal_trans PF04082.18 KIY63794.1 - 2.4e-29 102.2 0.0 3.6e-29 101.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain GST_N_2 PF13409.6 KIY63795.1 - 2e-09 37.6 0.0 2.3e-08 34.2 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KIY63795.1 - 5e-06 26.8 0.0 9.7e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KIY63795.1 - 2.4e-05 24.3 0.0 4.6e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KIY63795.1 - 0.00056 20.1 0.0 0.00094 19.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KIY63795.1 - 0.0026 18.4 0.0 0.008 16.9 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase N-terminal domain Tom37 PF10568.9 KIY63795.1 - 0.028 14.7 0.0 0.045 14.1 0.0 1.3 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein Zn_clus PF00172.18 KIY63796.1 - 0.002 18.2 6.0 0.0033 17.5 6.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KIY63797.1 - 1.7e-32 112.5 0.1 2.2e-32 112.2 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain BING4CT PF08149.11 KIY63799.1 - 2.4e-36 123.4 0.0 3e-35 119.9 0.0 2.7 3 0 0 3 3 3 1 BING4CT (NUC141) domain WD40 PF00400.32 KIY63799.1 - 2.5e-05 24.9 0.5 0.0013 19.5 0.0 3.8 5 0 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY63799.1 - 0.017 15.4 0.0 1.2 9.4 0.0 3.4 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain adh_short_C2 PF13561.6 KIY63801.1 - 2.6e-54 184.3 7.5 3.5e-54 183.8 7.5 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIY63801.1 - 1.1e-40 139.2 2.5 1.6e-40 138.6 2.5 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIY63801.1 - 3.2e-08 33.7 0.4 5e-08 33.1 0.4 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KIY63801.1 - 0.066 12.3 0.0 0.15 11.2 0.0 1.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Epimerase PF01370.21 KIY63801.1 - 0.19 11.2 1.9 0.32 10.4 0.7 2.0 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family bZIP_1 PF00170.21 KIY63802.1 - 1.2e-08 34.9 5.3 2.3e-08 34.0 5.3 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KIY63802.1 - 7.5e-08 32.3 7.7 1.5e-07 31.4 7.7 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KIY63802.1 - 0.0037 17.7 4.7 0.0088 16.5 4.7 1.6 1 0 0 1 1 1 1 bZIP Maf transcription factor PspB PF06667.12 KIY63802.1 - 0.91 9.6 2.0 18 5.5 0.3 2.8 3 0 0 3 3 3 0 Phage shock protein B Nucleo_P87 PF07267.11 KIY63802.1 - 4.5 6.0 5.6 8 5.2 5.6 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 F-box-like PF12937.7 KIY63803.1 - 0.00013 21.8 0.0 0.00036 20.4 0.0 1.8 1 0 0 1 1 1 1 F-box-like Pec_lyase_C PF00544.19 KIY63805.1 - 1e-11 44.9 9.1 5.1e-10 39.3 8.3 2.8 1 1 1 2 2 2 1 Pectate lyase Beta_helix PF13229.6 KIY63805.1 - 6e-07 29.4 15.6 0.0013 18.6 9.7 2.2 1 1 1 2 2 2 2 Right handed beta helix region BHD_3 PF10405.9 KIY63806.1 - 5.3e-30 103.7 0.0 7e-30 103.3 0.0 1.2 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_2 PF10404.9 KIY63806.1 - 0.015 16.3 0.1 0.034 15.1 0.1 1.6 1 0 0 1 1 1 0 Rad4 beta-hairpin domain 2 YwpF PF14183.6 KIY63806.1 - 0.032 14.2 0.0 0.057 13.4 0.0 1.4 2 0 0 2 2 2 0 YwpF-like protein PX PF00787.24 KIY63807.1 - 5.1e-20 71.5 0.0 1.3e-19 70.3 0.0 1.7 2 0 0 2 2 2 1 PX domain BAR_3_WASP_bdg PF10456.9 KIY63807.1 - 2.1e-16 60.1 0.9 3e-13 49.8 1.2 2.2 2 0 0 2 2 2 2 WASP-binding domain of Sorting nexin protein SH3_9 PF14604.6 KIY63807.1 - 1.6e-07 31.0 0.1 3.5e-07 30.0 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KIY63807.1 - 3.2e-07 29.8 0.0 5.8e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 SH3 domain RHD3 PF05879.12 KIY63807.1 - 0.033 12.3 0.1 1.4 7.0 0.0 2.0 2 0 0 2 2 2 0 Root hair defective 3 GTP-binding protein (RHD3) Acetyltransf_10 PF13673.7 KIY63808.1 - 8.1e-12 45.2 0.0 1.1e-11 44.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIY63808.1 - 2.9e-10 40.4 0.0 3.6e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KIY63808.1 - 1.8e-09 37.9 0.0 2.4e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIY63808.1 - 3.5e-07 30.1 0.0 5.8e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 KIY63808.1 - 2.4e-05 24.4 0.0 0.00017 21.7 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KIY63808.1 - 0.0013 19.4 0.0 0.0016 19.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KIY63808.1 - 0.0069 16.5 0.0 0.012 15.8 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_16 PF05301.11 KIY63808.1 - 0.11 12.2 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase, Mec-17 GNAT_acetyltr_2 PF13718.6 KIY63808.1 - 0.17 11.3 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase 2 RRM_1 PF00076.22 KIY63809.1 - 5.8e-23 80.5 0.0 1.5e-11 44.0 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KIY63809.1 - 2e-06 27.5 0.0 0.099 12.5 0.0 3.1 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_5 PF13893.6 KIY63809.1 - 3e-05 23.6 0.0 0.00057 19.5 0.0 2.3 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KIY63809.1 - 0.064 13.4 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif Sel_put PF04328.13 KIY63811.1 - 0.091 12.8 1.7 2.4 8.3 0.0 2.7 3 0 0 3 3 3 0 Selenoprotein, putative p450 PF00067.22 KIY63812.1 - 5.4e-61 206.7 0.0 6.9e-61 206.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_M19 PF01244.21 KIY63813.1 - 6.7e-105 350.8 0.0 8.3e-105 350.5 0.0 1.1 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) MFS_1 PF07690.16 KIY63814.1 - 5e-33 114.5 25.1 4.1e-32 111.5 25.9 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily zf-MYND PF01753.18 KIY63815.1 - 9.9e-08 32.0 15.6 1.7e-07 31.2 15.6 1.4 1 0 0 1 1 1 1 MYND finger Folate_rec PF03024.14 KIY63815.1 - 0.0019 18.1 4.0 0.0031 17.4 4.0 1.3 1 0 0 1 1 1 1 Folate receptor family Peptidase_S32 PF05579.13 KIY63818.1 - 0.00059 19.1 0.1 0.00099 18.4 0.1 1.2 1 0 0 1 1 1 1 Equine arteritis virus serine endopeptidase S32 Trypsin PF00089.26 KIY63818.1 - 0.043 13.6 0.1 0.084 12.7 0.1 1.5 1 0 0 1 1 1 0 Trypsin Trypsin_2 PF13365.6 KIY63818.1 - 0.12 13.2 0.1 16 6.4 0.0 2.7 2 1 0 2 2 2 0 Trypsin-like peptidase domain APH PF01636.23 KIY63819.1 - 1e-12 48.5 0.0 1.3e-12 48.2 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KIY63819.1 - 0.0018 17.9 0.0 0.0026 17.4 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.25 KIY63819.1 - 0.0024 17.3 0.0 0.12 11.7 0.0 2.5 2 1 1 3 3 3 1 Protein kinase domain DUF1679 PF07914.11 KIY63819.1 - 0.018 13.9 0.0 0.027 13.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Fructosamin_kin PF03881.14 KIY63819.1 - 0.024 13.8 0.0 0.034 13.4 0.0 1.2 1 0 0 1 1 1 0 Fructosamine kinase Kdo PF06293.14 KIY63819.1 - 0.084 12.2 0.1 0.13 11.6 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family EcKinase PF02958.20 KIY63819.1 - 0.14 11.4 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 Ecdysteroid kinase FAD_binding_3 PF01494.19 KIY63821.1 - 2.1e-14 53.5 0.9 1.6e-11 44.0 0.2 3.0 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KIY63821.1 - 2.2e-06 27.2 1.7 0.0026 17.0 0.2 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIY63821.1 - 0.00025 21.2 0.3 0.0015 18.7 0.2 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain SE PF08491.10 KIY63821.1 - 0.012 14.6 0.0 0.027 13.5 0.0 1.5 1 0 0 1 1 1 0 Squalene epoxidase Lycopene_cycl PF05834.12 KIY63821.1 - 0.03 13.4 0.1 2.1 7.3 0.0 2.4 3 0 0 3 3 3 0 Lycopene cyclase protein DAO PF01266.24 KIY63821.1 - 0.035 13.7 1.5 0.069 12.7 1.5 1.7 1 1 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KIY63821.1 - 0.075 13.0 0.1 3.3 7.7 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding BAR_2 PF10455.9 KIY63822.1 - 2.6e-44 151.5 0.4 1.7e-42 145.6 0.4 2.0 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 KIY63822.1 - 1.4e-14 54.3 1.3 4e-14 52.8 1.3 1.7 1 1 0 1 1 1 1 BAR domain BAR_3 PF16746.5 KIY63822.1 - 0.17 11.5 1.9 0.58 9.8 0.2 2.3 2 2 0 2 2 2 0 BAR domain of APPL family FAD_binding_3 PF01494.19 KIY63824.1 - 1.2e-14 54.3 0.4 1.1e-07 31.4 0.0 2.4 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KIY63824.1 - 1.1e-07 31.3 0.8 0.04 13.2 0.2 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KIY63824.1 - 0.0018 17.6 0.0 0.015 14.6 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 KIY63824.1 - 0.0027 16.8 0.1 0.024 13.7 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KIY63824.1 - 0.0098 16.1 0.1 0.031 14.5 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KIY63824.1 - 0.1 12.6 0.2 0.93 9.5 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding DAO PF01266.24 KIY63824.1 - 0.45 10.0 2.8 0.49 9.9 1.3 1.8 1 1 0 2 2 2 0 FAD dependent oxidoreductase Peptidase_S8 PF00082.22 KIY63825.1 - 2.4e-52 178.1 2.6 2.4e-52 178.1 2.6 1.9 2 0 0 2 2 2 1 Subtilase family fn3_5 PF06280.12 KIY63825.1 - 5.3e-16 59.3 2.4 1.2e-15 58.2 2.4 1.5 1 0 0 1 1 1 1 Fn3-like domain DUF11 PF01345.18 KIY63825.1 - 0.0018 18.6 0.3 0.006 16.9 0.3 1.9 1 0 0 1 1 1 1 Domain of unknown function DUF11 DUF916 PF06030.12 KIY63825.1 - 0.0053 16.8 0.5 0.01 15.9 0.5 1.3 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF916) FixG_C PF11614.8 KIY63825.1 - 0.013 15.7 0.1 0.049 13.8 0.1 2.0 1 0 0 1 1 1 0 IG-like fold at C-terminal of FixG, putative oxidoreductase RPT PF13446.6 KIY63825.1 - 0.19 11.7 0.0 0.43 10.5 0.0 1.5 1 0 0 1 1 1 0 A repeated domain in UCH-protein Rhabdo_ncap_2 PF03216.13 KIY63826.1 - 0.062 12.8 0.0 0.075 12.5 0.0 1.1 1 0 0 1 1 1 0 Rhabdovirus nucleoprotein F-box-like PF12937.7 KIY63828.1 - 0.055 13.4 0.0 0.055 13.4 0.0 3.1 4 0 0 4 4 4 0 F-box-like F-box PF00646.33 KIY63828.1 - 0.085 12.8 0.1 0.24 11.3 0.1 1.8 1 0 0 1 1 1 0 F-box domain DUF3450 PF11932.8 KIY63830.1 - 0.024 13.9 4.0 0.029 13.7 4.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) APG6_N PF17675.1 KIY63830.1 - 0.063 13.8 2.8 0.072 13.6 2.8 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region ADIP PF11559.8 KIY63830.1 - 0.078 13.1 6.5 0.089 12.9 6.5 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding TMF_DNA_bd PF12329.8 KIY63830.1 - 0.37 10.8 4.6 0.72 9.9 2.8 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding CENP-H PF05837.12 KIY63830.1 - 0.4 11.1 4.7 0.73 10.3 4.7 1.5 1 1 0 1 1 1 0 Centromere protein H (CENP-H) OPT PF03169.15 KIY63836.1 - 0.0012 17.6 0.0 0.0018 17.0 0.0 1.2 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Tyrosinase PF00264.20 KIY63838.1 - 4.4e-51 174.3 0.9 4.4e-51 174.3 0.9 1.4 2 0 0 2 2 2 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 KIY63838.1 - 1e-17 65.0 0.0 2.1e-17 63.9 0.0 1.4 1 0 0 1 1 1 1 Tyosinase C-terminal domain PNK3P PF08645.11 KIY63839.1 - 2.1e-43 147.8 0.0 4.7e-43 146.7 0.0 1.6 2 0 0 2 2 2 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 KIY63839.1 - 7.6e-18 65.1 0.3 7.3e-07 29.4 0.0 3.6 2 1 2 4 4 4 2 AAA domain HTH_Tnp_1 PF01527.20 KIY63839.1 - 0.00038 20.7 0.8 0.071 13.4 0.0 3.0 3 0 0 3 3 3 1 Transposase Hydrolase_6 PF13344.6 KIY63839.1 - 0.026 14.6 0.1 2.5 8.2 0.0 2.8 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase Zeta_toxin PF06414.12 KIY63839.1 - 0.038 13.3 0.0 5.3 6.3 0.1 2.3 1 1 0 2 2 2 0 Zeta toxin Ribosomal_L1 PF00687.21 KIY63840.1 - 8e-56 189.0 0.4 1.9e-55 187.7 0.4 1.7 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family AAA PF00004.29 KIY63841.1 - 2.4e-39 134.8 0.3 3.7e-39 134.2 0.0 1.5 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KIY63841.1 - 4.5e-09 36.0 0.0 1.1e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 KIY63841.1 - 6.1e-07 29.3 0.0 1.2e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KIY63841.1 - 8.8e-06 25.8 0.1 3e-05 24.0 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KIY63841.1 - 9.9e-06 26.0 0.1 0.0006 20.2 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 KIY63841.1 - 1.1e-05 25.5 0.0 2.3e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 KIY63841.1 - 1.9e-05 24.8 0.0 4.7e-05 23.6 0.0 1.6 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 KIY63841.1 - 0.0001 22.5 0.0 0.00026 21.2 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.6 KIY63841.1 - 0.00016 22.0 0.3 0.002 18.4 0.3 2.4 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KIY63841.1 - 0.00021 20.7 0.2 0.0017 17.7 0.3 2.0 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI TniB PF05621.11 KIY63841.1 - 0.00043 19.7 0.0 0.74 9.2 0.0 2.3 1 1 1 2 2 2 2 Bacterial TniB protein AAA_25 PF13481.6 KIY63841.1 - 0.00055 19.6 0.4 0.13 11.8 0.1 2.8 2 1 1 3 3 3 1 AAA domain TIP49 PF06068.13 KIY63841.1 - 0.001 18.3 0.0 0.0016 17.7 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain Rad17 PF03215.15 KIY63841.1 - 0.0011 18.9 0.1 0.0032 17.4 0.1 1.7 1 1 0 1 1 1 1 Rad17 P-loop domain RNA_helicase PF00910.22 KIY63841.1 - 0.0012 19.2 0.0 0.003 17.9 0.0 1.8 1 1 0 1 1 1 1 RNA helicase AAA_24 PF13479.6 KIY63841.1 - 0.0018 18.0 0.1 0.0032 17.2 0.1 1.4 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KIY63841.1 - 0.0036 17.1 0.0 0.0062 16.3 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 KIY63841.1 - 0.0058 17.2 0.0 0.011 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 KIY63841.1 - 0.0078 15.9 0.0 0.028 14.1 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain TsaE PF02367.17 KIY63841.1 - 0.01 15.8 0.0 0.022 14.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 KIY63841.1 - 0.013 15.0 0.6 0.031 13.8 0.1 2.0 2 1 0 2 2 2 0 P-loop containing dynein motor region AAA_17 PF13207.6 KIY63841.1 - 0.016 15.6 0.1 0.034 14.6 0.1 1.5 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 KIY63841.1 - 0.017 14.9 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase SKI PF01202.22 KIY63841.1 - 0.019 15.1 0.5 0.46 10.6 0.1 2.3 2 0 0 2 2 2 0 Shikimate kinase ATPase_2 PF01637.18 KIY63841.1 - 0.019 14.9 0.0 0.07 13.0 0.0 1.8 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea FCH PF00611.23 KIY63841.1 - 0.021 15.1 0.0 0.057 13.7 0.0 1.8 1 0 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain ABC_tran PF00005.27 KIY63841.1 - 0.021 15.4 0.0 0.048 14.2 0.0 1.8 1 1 0 1 1 1 0 ABC transporter NACHT PF05729.12 KIY63841.1 - 0.022 14.7 0.1 0.044 13.7 0.1 1.5 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.6 KIY63841.1 - 0.022 15.0 0.1 0.051 13.8 0.1 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KIY63841.1 - 0.022 14.0 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Zeta toxin Parvo_NS1 PF01057.17 KIY63841.1 - 0.023 13.8 0.0 0.035 13.2 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AFG1_ATPase PF03969.16 KIY63841.1 - 0.027 13.4 0.0 1.1 8.0 0.0 2.2 2 0 0 2 2 2 0 AFG1-like ATPase Ldl_recept_b PF00058.17 KIY63841.1 - 0.029 14.9 0.9 18 5.9 0.0 4.1 5 0 0 5 5 4 0 Low-density lipoprotein receptor repeat class B tRNA_lig_kinase PF08303.11 KIY63841.1 - 0.029 14.5 0.0 0.1 12.7 0.0 1.7 2 0 0 2 2 2 0 tRNA ligase kinase domain AAA_3 PF07726.11 KIY63841.1 - 0.035 14.0 0.0 0.094 12.6 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Bac_DnaA PF00308.18 KIY63841.1 - 0.036 13.9 0.0 0.079 12.8 0.0 1.5 1 1 0 1 1 1 0 Bacterial dnaA protein ATPase PF06745.13 KIY63841.1 - 0.043 13.2 0.1 1.4 8.2 0.0 2.2 1 1 1 2 2 2 0 KaiC Sigma54_activ_2 PF14532.6 KIY63841.1 - 0.046 13.8 0.0 0.089 12.9 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF815 PF05673.13 KIY63841.1 - 0.05 12.8 0.0 0.078 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Hydin_ADK PF17213.3 KIY63841.1 - 0.13 12.5 0.6 1 9.6 0.1 2.1 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain NB-ARC PF00931.22 KIY63841.1 - 0.24 10.6 0.0 0.43 9.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain PBP PF01161.20 KIY63842.1 - 7.1e-11 42.5 0.2 2e-10 41.1 0.1 1.8 2 0 0 2 2 2 1 Phosphatidylethanolamine-binding protein FH2 PF02181.23 KIY63845.1 - 8.3e-75 252.2 4.2 8.3e-75 252.2 4.2 1.7 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 KIY63845.1 - 9.8e-35 119.9 0.3 3.4e-34 118.2 0.3 1.9 1 0 0 1 1 1 1 Diaphanous FH3 Domain Drf_GBD PF06371.13 KIY63845.1 - 2e-31 109.0 0.9 7.7e-31 107.1 0.0 2.4 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain DUF1664 PF07889.12 KIY63845.1 - 0.35 10.9 4.2 11 6.0 0.3 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 KIY63845.1 - 0.61 10.3 4.9 1.1 9.5 0.1 3.3 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family T6SS_VipA PF05591.12 KIY63845.1 - 1.7 8.4 5.3 1.3 8.8 0.6 2.9 3 0 0 3 3 3 0 Type VI secretion system, VipA, VC_A0107 or Hcp2 TPR_MLP1_2 PF07926.12 KIY63845.1 - 2.6 8.1 18.1 0.32 11.1 0.4 4.1 3 1 1 4 4 4 0 TPR/MLP1/MLP2-like protein Pox_Ag35 PF03286.14 KIY63846.1 - 3 7.6 10.1 8.5 6.1 1.5 2.4 2 0 0 2 2 2 0 Pox virus Ag35 surface protein FH2 PF02181.23 KIY63847.1 - 1.5e-83 281.0 0.0 1.5e-83 281.0 0.0 2.7 2 1 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.13 KIY63847.1 - 3.3e-28 98.5 0.2 4.1e-27 95.0 0.2 2.6 1 1 0 1 1 1 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 KIY63847.1 - 9.7e-17 61.2 0.7 3.7e-16 59.3 0.7 2.0 1 0 0 1 1 1 1 Diaphanous FH3 Domain APG6_N PF17675.1 KIY63847.1 - 0.065 13.8 0.1 0.065 13.8 0.1 4.5 3 1 0 3 3 3 0 Apg6 coiled-coil region TolA_bind_tri PF16331.5 KIY63847.1 - 0.57 10.3 8.0 5.5 7.1 0.2 3.1 2 0 0 2 2 2 0 TolA binding protein trimerisation Spc7 PF08317.11 KIY63847.1 - 3.2 6.5 20.6 1.9 7.3 0.2 2.4 2 0 0 2 2 2 0 Spc7 kinetochore protein JIP_LZII PF16471.5 KIY63847.1 - 3.9 7.7 9.0 1.8 8.8 1.3 3.7 3 0 0 3 3 3 0 JNK-interacting protein leucine zipper II FlxA PF14282.6 KIY63847.1 - 5.1 7.2 15.8 0.28 11.2 3.7 3.3 3 0 0 3 3 3 0 FlxA-like protein SOGA PF11365.8 KIY63847.1 - 6.3 8.0 18.8 0.24 12.6 3.0 3.1 2 1 1 3 3 3 0 Protein SOGA LAG1-DNAbind PF09271.11 KIY63848.1 - 4.4e-27 95.6 0.3 2e-16 61.0 0.1 2.3 1 1 1 2 2 2 2 LAG1, DNA binding BTD PF09270.10 KIY63848.1 - 1.5e-26 93.5 0.0 3e-26 92.5 0.0 1.5 1 0 0 1 1 1 1 Beta-trefoil DNA-binding domain GPP34 PF05719.11 KIY63849.1 - 9.3e-55 185.8 0.1 1.2e-54 185.5 0.1 1.2 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) p450 PF00067.22 KIY63850.1 - 1.4e-13 50.4 0.0 1.7e-13 50.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ADIP PF11559.8 KIY63851.1 - 1.3e-22 80.5 7.4 1.3e-22 80.5 7.4 3.3 2 1 0 3 3 3 1 Afadin- and alpha -actinin-Binding AAA_10 PF12846.7 KIY63851.1 - 1.3 7.9 8.1 0.062 12.2 1.0 1.9 2 0 0 2 2 2 0 AAA-like domain 2OG-FeII_Oxy_2 PF13532.6 KIY63854.1 - 3.2e-25 89.5 0.0 4.2e-25 89.1 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF872 PF05915.12 KIY63855.1 - 0.25 11.5 1.1 0.53 10.5 1.1 1.5 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) UCH PF00443.29 KIY63856.1 - 8.3e-45 153.3 0.0 1.4e-44 152.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KIY63856.1 - 6.7e-14 52.2 0.0 9.9e-11 41.8 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.20 KIY63856.1 - 4.7e-06 27.1 0.0 1.1e-05 25.9 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain Kv2channel PF03521.14 KIY63856.1 - 0.0022 17.4 0.4 0.004 16.6 0.4 1.4 1 0 0 1 1 1 1 Kv2 voltage-gated K+ channel DNA_pol_delta_4 PF04081.13 KIY63857.1 - 6.2e-26 91.3 0.2 9.8e-26 90.6 0.2 1.5 1 1 0 1 1 1 1 DNA polymerase delta, subunit 4 F-box-like PF12937.7 KIY63858.1 - 0.0093 15.8 0.4 0.023 14.6 0.4 1.7 1 0 0 1 1 1 1 F-box-like Tcf25 PF04910.14 KIY63859.1 - 9.9e-92 307.7 0.0 1.3e-91 307.3 0.0 1.2 1 0 0 1 1 1 1 Transcriptional repressor TCF25 TPR_7 PF13176.6 KIY63859.1 - 0.14 12.2 0.1 0.39 10.8 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat XAP5 PF04921.14 KIY63859.1 - 1.2 8.9 6.6 2.8 7.7 6.6 1.5 1 0 0 1 1 1 0 XAP5, circadian clock regulator SRP-alpha_N PF04086.13 KIY63859.1 - 4 7.3 13.8 7.2 6.4 13.8 1.4 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal CDC45 PF02724.14 KIY63859.1 - 4.9 5.3 13.8 0.082 11.2 5.8 1.8 2 0 0 2 2 2 0 CDC45-like protein Mitofilin PF09731.9 KIY63859.1 - 5.2 5.8 13.7 8.4 5.1 13.7 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein p450 PF00067.22 KIY63860.1 - 2.2e-27 96.0 1.9 7.1e-13 48.1 0.0 2.6 1 1 1 3 3 3 2 Cytochrome P450 PRP21_like_P PF12230.8 KIY63860.1 - 0.091 12.6 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein p450 PF00067.22 KIY63861.1 - 4.6e-57 193.8 0.0 5.5e-57 193.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PrkA PF06798.12 KIY63861.1 - 0.022 14.4 0.2 0.16 11.6 0.1 2.0 2 0 0 2 2 2 0 PrkA serine protein kinase C-terminal domain SSP160 PF06933.11 KIY63865.1 - 6.4 4.9 9.4 7.3 4.6 9.4 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 SufE PF02657.15 KIY63867.1 - 0.059 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Fe-S metabolism associated domain PPR_2 PF13041.6 KIY63868.1 - 0.53 10.5 1.7 18 5.6 0.0 3.7 5 0 0 5 5 5 0 PPR repeat family HLH PF00010.26 KIY63870.1 - 1.7e-14 53.5 0.1 2.8e-14 52.8 0.1 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF4363 PF14276.6 KIY63870.1 - 0.036 14.2 0.7 0.94 9.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) 60KD_IMP PF02096.20 KIY63871.1 - 1.7e-09 37.8 1.0 2.4e-09 37.3 1.0 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein DUF1365 PF07103.11 KIY63872.1 - 1.3e-61 208.3 0.0 2.4e-61 207.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1365) Bim_N PF06773.11 KIY63872.1 - 0.017 14.8 0.6 0.042 13.5 0.6 1.7 1 0 0 1 1 1 0 Bim protein N-terminus zf-UDP PF14569.6 KIY63874.1 - 0.00014 21.9 0.5 0.00017 21.7 0.5 1.1 1 0 0 1 1 1 1 Zinc-binding RING-finger RINGv PF12906.7 KIY63874.1 - 0.0096 16.0 6.5 0.016 15.3 6.5 1.4 1 0 0 1 1 1 1 RING-variant domain zf-CSL PF05207.13 KIY63874.1 - 0.028 14.1 0.3 0.11 12.2 0.3 2.0 1 1 1 2 2 2 0 CSL zinc finger FANCL_C PF11793.8 KIY63876.1 - 3.5e-07 30.3 2.6 5.8e-07 29.6 2.6 1.3 1 0 0 1 1 1 1 FANCL C-terminal domain RINGv PF12906.7 KIY63876.1 - 1.5e-05 25.0 6.5 2.6e-05 24.3 6.5 1.4 1 0 0 1 1 1 1 RING-variant domain zf-UDP PF14569.6 KIY63876.1 - 0.00036 20.6 0.4 0.0007 19.7 0.4 1.4 1 0 0 1 1 1 1 Zinc-binding RING-finger zf-RING_2 PF13639.6 KIY63876.1 - 0.0031 17.8 4.7 0.0048 17.2 4.7 1.3 1 0 0 1 1 1 1 Ring finger domain Zn_ribbon_17 PF17120.5 KIY63876.1 - 0.38 10.4 3.3 0.77 9.4 3.3 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 KIY63876.1 - 0.64 9.9 5.0 1.4 8.8 5.0 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Sod_Cu PF00080.20 KIY63877.1 - 4.5e-44 150.1 1.6 5.7e-44 149.7 1.6 1.1 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) zf-H2C2_5 PF13909.6 KIY63878.1 - 1.5e-21 75.8 27.6 2.7e-08 33.4 0.1 6.8 7 0 0 7 7 7 6 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 KIY63878.1 - 2.7e-21 75.0 28.2 9.3e-07 29.0 0.0 7.4 8 0 0 8 8 8 3 Zinc-finger double domain zf-C2H2 PF00096.26 KIY63878.1 - 4.2e-16 58.4 22.5 0.0007 19.9 0.4 6.2 6 0 0 6 6 6 5 Zinc finger, C2H2 type OrsD PF12013.8 KIY63878.1 - 1.8e-06 28.4 15.2 1.7 9.1 0.2 6.0 4 1 1 6 6 6 3 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_4 PF13894.6 KIY63878.1 - 1.5e-05 25.4 22.9 0.067 14.1 0.4 6.4 6 0 0 6 6 6 2 C2H2-type zinc finger FOXP-CC PF16159.5 KIY63878.1 - 9.5e-05 22.9 10.0 0.36 11.5 0.2 3.7 3 1 1 4 4 4 3 FOXP coiled-coil domain zf_C2H2_ZHX PF18387.1 KIY63878.1 - 0.0099 15.5 11.7 0.95 9.1 0.1 4.9 4 2 2 6 6 6 3 Zinc-fingers and homeoboxes C2H2 finger domain Zap1_zf2 PF18217.1 KIY63878.1 - 3.1 7.9 19.2 3.2 7.8 1.3 4.2 4 0 0 4 4 4 0 Zap1 zinc finger 2 ANAPC4_WD40 PF12894.7 KIY63879.1 - 0.065 13.5 0.0 2.1 8.7 0.0 3.0 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KIY63879.1 - 0.085 13.8 6.5 92 4.2 0.0 5.4 6 0 0 6 6 6 0 WD domain, G-beta repeat Sod_Cu PF00080.20 KIY63880.1 - 1.7e-39 135.3 2.5 2.1e-39 135.0 2.5 1.1 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) HdeA PF06411.11 KIY63881.1 - 0.25 11.6 4.8 0.074 13.2 1.4 1.9 2 0 0 2 2 2 0 HdeA/HdeB family 60KD_IMP PF02096.20 KIY63882.1 - 2.4e-08 34.1 2.4 4.3e-08 33.2 2.4 1.5 1 0 0 1 1 1 1 60Kd inner membrane protein Nudix_N_2 PF14803.6 KIY63884.1 - 0.013 15.4 0.5 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Nudix N-terminal F-box-like PF12937.7 KIY63884.1 - 0.014 15.3 0.7 0.024 14.5 0.7 1.4 1 0 0 1 1 1 0 F-box-like ASXH PF13919.6 KIY63885.1 - 2.7e-19 69.6 4.4 4.7e-18 65.5 4.4 2.2 1 1 0 1 1 1 1 Asx homology domain tRNA-synt_1 PF00133.22 KIY63886.1 - 3.6e-214 712.5 0.0 4.6e-213 708.8 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KIY63886.1 - 5.6e-36 123.8 0.3 1.4e-35 122.5 0.3 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KIY63886.1 - 1e-13 50.8 0.0 1.9e-06 26.9 0.0 4.4 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 KIY63886.1 - 1e-11 44.7 0.1 4.6e-08 32.8 0.1 2.6 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 KIY63886.1 - 0.021 14.2 0.0 0.14 11.5 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain DUF883 PF05957.13 KIY63886.1 - 0.55 10.9 5.5 1.6 9.4 5.5 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) DUF3275 PF11679.8 KIY63886.1 - 1.7 8.5 3.6 3.3 7.6 3.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) DUF1524 PF07510.11 KIY63887.1 - 1.3e-08 34.8 0.0 1.5e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) HNH_4 PF13395.6 KIY63887.1 - 0.51 10.3 2.3 7.3 6.6 2.3 2.2 1 1 0 1 1 1 0 HNH endonuclease LPMO_10 PF03067.15 KIY63888.1 - 1.1e-09 39.3 1.0 1.4e-09 38.9 1.0 1.1 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading DUF4451 PF14616.6 KIY63889.1 - 6.3e-10 39.3 0.6 7.1e-10 39.1 0.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) zf-B_box PF00643.24 KIY63889.1 - 0.0062 16.7 0.5 0.014 15.5 0.1 1.7 2 0 0 2 2 2 1 B-box zinc finger DUF4451 PF14616.6 KIY63890.1 - 4.8e-09 36.5 0.0 7.6e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) RRM_1 PF00076.22 KIY63892.1 - 0.00014 21.6 0.0 0.00027 20.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Slu7 PF11708.8 KIY63892.1 - 0.045 13.5 1.8 4 7.1 0.0 2.2 2 0 0 2 2 2 0 Pre-mRNA splicing Prp18-interacting factor S10_plectin PF03501.15 KIY63893.1 - 2.4e-44 149.3 0.2 2.9e-44 149.1 0.2 1.1 1 0 0 1 1 1 1 Plectin/S10 domain TrmB PF01978.19 KIY63893.1 - 0.078 12.9 0.0 0.12 12.3 0.0 1.4 1 1 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB E1_FCCH PF16190.5 KIY63894.1 - 0.051 13.8 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-activating enzyme E1 FCCH domain Ubiq_cyt_C_chap PF03981.12 KIY63896.1 - 2e-20 73.3 0.5 6.3e-10 39.3 0.1 2.9 2 1 0 2 2 2 2 Ubiquinol-cytochrome C chaperone Nodulin PF02451.15 KIY63896.1 - 0.1 12.0 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Nodulin ATP-synt_G PF04718.15 KIY63897.1 - 3.9e-12 46.9 0.5 2.6e-11 44.2 0.0 2.3 2 1 0 2 2 2 1 Mitochondrial ATP synthase g subunit baeRF_family3 PF18845.1 KIY63897.1 - 0.11 12.8 0.7 0.17 12.2 0.7 1.2 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 3 RVT_1 PF00078.27 KIY63898.1 - 4.3e-06 26.4 0.0 8.9e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RING_2 PF13639.6 KIY63904.1 - 1.4e-07 31.7 7.9 2.2e-07 31.1 7.9 1.3 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 KIY63904.1 - 1.5e-06 28.2 5.4 3.5e-06 27.1 5.4 1.6 1 1 0 1 1 1 1 FANCL C-terminal domain C1_1 PF00130.22 KIY63904.1 - 0.0017 18.2 1.4 0.0017 18.2 1.4 2.0 1 1 1 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-ANAPC11 PF12861.7 KIY63904.1 - 0.0017 18.3 7.3 0.005 16.9 7.3 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KIY63904.1 - 0.0066 16.7 11.5 0.034 14.4 11.2 2.1 1 1 1 2 2 2 1 RING-H2 zinc finger domain zf-RING-like PF08746.11 KIY63904.1 - 0.015 15.6 7.0 0.04 14.2 7.0 1.7 1 1 0 1 1 1 0 RING-like domain Zn_ribbon_17 PF17120.5 KIY63904.1 - 0.068 12.8 6.8 0.15 11.7 6.8 1.6 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4 PF00097.25 KIY63904.1 - 0.069 13.0 8.0 0.24 11.3 8.3 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KIY63904.1 - 0.07 13.0 10.0 0.18 11.7 10.0 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zf_RING PF16744.5 KIY63904.1 - 0.088 12.9 4.9 0.21 11.7 4.9 1.7 1 1 0 1 1 1 0 KIAA1045 RING finger RINGv PF12906.7 KIY63904.1 - 0.22 11.7 10.6 0.45 10.7 9.8 1.9 1 1 1 2 2 2 0 RING-variant domain YdjO PF14169.6 KIY63904.1 - 0.27 11.0 4.2 0.51 10.1 2.3 2.2 2 1 0 2 2 2 0 Cold-inducible protein YdjO zf-RING_4 PF14570.6 KIY63904.1 - 0.69 9.7 5.1 1.7 8.5 5.1 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 KIY63904.1 - 3.9 7.4 8.8 38 4.3 8.8 2.5 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TPR_10 PF13374.6 KIY63906.1 - 1.7e-09 37.2 0.1 0.012 15.4 0.0 4.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 KIY63906.1 - 7.2e-06 26.4 0.8 0.44 11.5 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 KIY63906.1 - 1.3e-05 25.8 2.1 0.0007 20.2 0.2 3.7 2 2 2 4 4 4 2 Tetratricopeptide repeat SHNi-TPR PF10516.9 KIY63906.1 - 0.00059 19.2 0.0 0.17 11.4 0.0 2.5 2 0 0 2 2 2 2 SHNi-TPR TPR_19 PF14559.6 KIY63906.1 - 0.056 14.0 0.2 29 5.3 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KIY63906.1 - 0.056 13.6 0.0 15 6.0 0.0 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat F-box-like PF12937.7 KIY63910.1 - 2.2e-09 37.1 0.6 3.4e-09 36.5 0.6 1.3 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY63910.1 - 0.031 14.1 2.9 3.5 7.6 0.6 2.3 2 0 0 2 2 2 0 F-box domain F-box-like_2 PF13013.6 KIY63910.1 - 0.071 13.1 0.1 0.11 12.5 0.1 1.4 1 1 0 1 1 1 0 F-box-like domain zf-MYND PF01753.18 KIY63911.1 - 5.6e-06 26.3 10.1 1.2e-05 25.3 10.1 1.6 1 0 0 1 1 1 1 MYND finger His_Phos_1 PF00300.22 KIY63913.1 - 1.7e-25 89.9 0.0 2.3e-25 89.5 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Asp PF00026.23 KIY63915.1 - 2.4e-22 79.8 0.1 3.3e-15 56.3 0.0 3.1 1 1 1 2 2 2 2 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 KIY63915.1 - 9.7e-11 42.2 0.1 0.00098 19.7 0.0 3.6 3 1 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.6 KIY63915.1 - 0.00046 20.7 0.0 1.2 9.8 0.0 3.3 3 0 0 3 3 3 2 gag-polyprotein putative aspartyl protease Rhabdo_glycop PF00974.18 KIY63915.1 - 0.041 12.3 0.0 0.069 11.6 0.0 1.3 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein TAXi_N PF14543.6 KIY63915.1 - 0.044 14.0 0.2 0.49 10.6 0.0 2.2 1 1 1 2 2 2 0 Xylanase inhibitor N-terminal Asp PF00026.23 KIY63916.1 - 1.6e-20 73.7 5.0 4.6e-18 65.7 5.0 3.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 KIY63916.1 - 0.0031 18.1 0.3 0.05 14.2 0.2 3.0 4 0 0 4 4 4 1 Aspartyl protease gag-asp_proteas PF13975.6 KIY63916.1 - 0.0041 17.6 0.0 0.82 10.3 0.0 2.7 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Tweety PF04906.13 KIY63916.1 - 0.0056 15.4 0.3 0.0087 14.8 0.3 1.2 1 0 0 1 1 1 1 Tweety stn_TNFRSF12A PF12191.8 KIY63916.1 - 0.2 11.9 0.1 1.1 9.5 0.1 2.1 2 0 0 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Glyco_hydro_15 PF00723.21 KIY63917.1 - 2.5e-98 329.8 0.6 2.9e-98 329.6 0.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.19 KIY63917.1 - 6.5e-30 102.9 0.2 1.4e-29 101.8 0.2 1.6 1 0 0 1 1 1 1 Starch binding domain DUF4950 PF16308.5 KIY63917.1 - 0.0079 16.2 0.1 0.015 15.3 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4950) Ysc84 PF04366.12 KIY63919.1 - 1.2e-44 151.2 0.0 2.1e-44 150.4 0.0 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator Sec7 PF01369.20 KIY63919.1 - 0.015 14.9 0.0 0.025 14.3 0.0 1.2 1 0 0 1 1 1 0 Sec7 domain Pkinase PF00069.25 KIY63922.1 - 4.2e-11 42.7 0.0 3e-10 39.9 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KIY63922.1 - 2.1e-07 30.1 0.0 2.6e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 KIY63922.1 - 1.1e-05 24.9 0.0 2.5e-05 23.7 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase zf-CCCH_4 PF18044.1 KIY63923.1 - 1.6e-11 43.7 17.7 8e-06 25.5 0.3 4.1 4 0 0 4 4 4 3 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KIY63923.1 - 9.6e-09 35.0 14.9 0.00023 21.1 2.8 4.0 3 2 0 3 3 3 3 Zinc finger domain zf-CCCH PF00642.24 KIY63923.1 - 3.2e-07 30.1 19.4 7.1e-06 25.8 2.0 3.6 3 1 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 KIY63923.1 - 0.00035 20.9 12.9 0.016 15.6 1.0 3.6 3 0 0 3 3 3 3 RNA-binding, Nab2-type zinc finger Torus PF16131.5 KIY63923.1 - 0.00078 20.1 12.3 0.24 12.1 1.3 3.3 2 1 1 3 3 3 2 Torus domain zf-CCCH_3 PF15663.5 KIY63923.1 - 0.016 15.5 6.3 0.023 14.9 0.9 2.3 2 0 0 2 2 2 0 Zinc-finger containing family Heme_oxygenase PF01126.20 KIY63924.1 - 6.7e-44 150.1 0.1 8.3e-44 149.8 0.1 1.1 1 0 0 1 1 1 1 Heme oxygenase ArAE_2_N PF10337.9 KIY63925.1 - 0.12 11.3 0.0 0.18 10.8 0.0 1.1 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal Methyltransf_33 PF10017.9 KIY63926.1 - 3.4e-72 243.2 0.0 6.9e-72 242.2 0.0 1.5 1 1 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.16 KIY63926.1 - 1.2e-22 80.8 2.5 5e-12 45.9 0.1 2.3 2 0 0 2 2 2 2 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 KIY63926.1 - 0.00028 21.4 0.3 0.00057 20.4 0.3 1.6 1 0 0 1 1 1 1 DinB superfamily F-box-like PF12937.7 KIY63928.1 - 1.1e-10 41.2 3.0 3.9e-10 39.5 0.5 2.8 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 KIY63928.1 - 1.3 8.9 16.6 0.075 12.9 3.9 4.4 4 1 0 4 4 4 0 F-box domain WD40 PF00400.32 KIY63929.1 - 1.4e-41 139.6 16.8 8.3e-08 32.8 0.0 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY63929.1 - 1.4e-22 79.8 0.1 3.3e-06 27.3 0.0 6.7 1 1 6 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIY63929.1 - 1.2e-09 38.3 0.1 0.00032 20.6 0.0 3.4 1 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KIY63929.1 - 2.7e-05 23.3 0.2 0.43 9.5 0.1 3.5 2 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein IKI3 PF04762.12 KIY63929.1 - 0.0024 15.9 0.3 0.0038 15.3 0.3 1.3 1 0 0 1 1 1 1 IKI3 family Coatomer_WDAD PF04053.14 KIY63929.1 - 0.017 14.2 0.0 0.023 13.8 0.0 1.2 1 0 0 1 1 1 0 Coatomer WD associated region VID27 PF08553.10 KIY63929.1 - 0.066 12.3 0.0 0.17 10.9 0.0 1.5 2 0 0 2 2 2 0 VID27 C-terminal WD40-like domain Ank_2 PF12796.7 KIY63930.1 - 2.2e-11 44.2 0.0 2.2e-07 31.3 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KIY63930.1 - 9.6e-06 26.1 0.1 0.00019 22.0 0.0 1.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIY63930.1 - 1.2e-05 25.3 0.0 0.21 12.3 0.0 3.8 3 1 1 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 KIY63930.1 - 0.0011 19.2 0.1 0.13 12.6 0.0 2.9 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 KIY63930.1 - 0.0025 18.2 0.3 0.53 10.8 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat F-box-like PF12937.7 KIY63931.1 - 3.5e-09 36.4 0.6 1.2e-08 34.7 0.6 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY63931.1 - 0.004 17.0 2.0 0.042 13.7 1.3 2.7 2 1 0 2 2 2 1 F-box domain F-box-like PF12937.7 KIY63932.1 - 8.7e-08 31.9 0.4 3.5e-07 30.0 0.4 2.1 1 0 0 1 1 1 1 F-box-like TSC22 PF01166.18 KIY63932.1 - 0.12 12.7 0.0 0.35 11.2 0.0 1.7 1 0 0 1 1 1 0 TSC-22/dip/bun family F-box PF00646.33 KIY63932.1 - 0.21 11.5 4.2 0.63 10.0 2.0 3.0 2 1 0 2 2 2 0 F-box domain LRR_4 PF12799.7 KIY63933.1 - 0.03 14.8 2.7 0.39 11.2 0.2 3.5 4 2 2 6 6 6 0 Leucine Rich repeats (2 copies) PBP1_TM PF14812.6 KIY63933.1 - 0.47 10.8 5.9 0.88 10.0 5.9 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Cwf_Cwc_15 PF04889.12 KIY63933.1 - 0.54 9.9 4.2 0.81 9.4 4.2 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 KIY63933.1 - 8 5.7 6.7 11 5.2 6.7 1.1 1 0 0 1 1 1 0 NOA36 protein DUF2457 PF10446.9 KIY63933.1 - 8.1 5.5 7.7 12 5.0 7.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) MFS_1 PF07690.16 KIY63934.1 - 5.5e-29 101.2 23.3 3.5e-27 95.3 25.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Proteasome PF00227.26 KIY63935.1 - 5.8e-59 198.8 0.0 9.1e-59 198.1 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KIY63935.1 - 8.8e-14 50.9 0.5 3.2e-13 49.1 0.1 2.2 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Peptidase_C78 PF07910.13 KIY63936.1 - 4e-45 153.9 0.0 5.1e-45 153.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C78 Piwi PF02171.17 KIY63938.1 - 1.7e-58 198.2 0.0 2.6e-58 197.6 0.0 1.3 1 0 0 1 1 1 1 Piwi domain ArgoL1 PF08699.10 KIY63938.1 - 1.7e-13 50.0 0.0 5.4e-13 48.4 0.0 2.0 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoN PF16486.5 KIY63938.1 - 6.5e-10 39.8 0.0 1.4e-09 38.7 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoMid PF16487.5 KIY63938.1 - 0.0004 20.6 0.1 0.0014 18.9 0.0 2.0 2 0 0 2 2 2 1 Mid domain of argonaute ArgoL2 PF16488.5 KIY63938.1 - 0.00046 20.5 0.1 0.0014 18.9 0.1 2.0 1 0 0 1 1 1 1 Argonaute linker 2 domain PAZ PF02170.22 KIY63938.1 - 0.00047 20.0 0.0 0.0009 19.1 0.0 1.4 1 0 0 1 1 1 1 PAZ domain AMP-binding PF00501.28 KIY63940.1 - 1e-87 294.5 0.1 1.4e-87 294.0 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KIY63940.1 - 0.008 17.1 0.4 0.02 15.9 0.4 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ApoA-II PF04711.13 KIY63941.1 - 0.041 14.0 0.2 0.16 12.1 0.0 2.0 2 1 0 2 2 2 0 Apolipoprotein A-II (ApoA-II) CREPT PF16566.5 KIY63941.1 - 0.084 13.0 3.5 0.25 11.5 2.6 1.8 1 1 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour CompInhib_SCIN PF11546.8 KIY63941.1 - 0.14 12.2 1.3 3.5 7.7 0.2 2.8 1 1 2 3 3 3 0 Staphylococcal complement inhibitor SCIN AAA_23 PF13476.6 KIY63941.1 - 0.15 12.6 4.8 0.25 11.8 4.8 1.3 1 1 0 1 1 1 0 AAA domain Cyclin_N PF00134.23 KIY63942.1 - 7.6e-10 38.6 0.2 6.7e-09 35.6 0.1 2.3 2 1 0 2 2 2 1 Cyclin, N-terminal domain ImcF-related_N PF14331.6 KIY63943.1 - 0.15 11.4 0.0 0.37 10.1 0.0 1.6 1 0 0 1 1 1 0 ImcF-related N-terminal domain Ras PF00071.22 KIY63944.1 - 3.1e-65 218.7 0.9 3.6e-65 218.5 0.9 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIY63944.1 - 5e-37 126.8 0.5 1.7e-36 125.1 0.1 1.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIY63944.1 - 4.1e-17 62.2 0.2 4.8e-17 61.9 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KIY63944.1 - 2.9e-06 27.3 0.4 0.051 13.5 0.1 2.3 1 1 1 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KIY63944.1 - 1.3e-05 24.8 0.3 4e-05 23.2 0.1 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KIY63944.1 - 2e-05 24.1 0.0 2.3e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KIY63944.1 - 2.5e-05 24.3 0.0 6.2e-05 23.1 0.0 1.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.10 KIY63944.1 - 3.4e-05 23.4 0.1 4.1e-05 23.1 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 KIY63944.1 - 0.0066 16.0 0.0 0.034 13.7 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.6 KIY63944.1 - 0.0073 16.7 0.0 0.01 16.2 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KIY63944.1 - 0.0077 16.7 0.1 0.48 10.8 0.0 2.3 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF3873 PF12989.7 KIY63944.1 - 0.017 15.5 0.1 0.035 14.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3873) AAA_5 PF07728.14 KIY63944.1 - 0.037 14.0 0.0 0.06 13.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 KIY63944.1 - 0.048 13.4 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 KIY63944.1 - 0.053 13.0 0.0 0.18 11.3 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_22 PF13401.6 KIY63944.1 - 0.055 13.7 0.0 0.089 13.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain Septin PF00735.18 KIY63944.1 - 0.086 12.1 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Septin PduV-EutP PF10662.9 KIY63944.1 - 0.089 12.5 0.1 1.3 8.8 0.0 2.2 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 KIY63944.1 - 0.1 13.1 0.0 0.14 12.7 0.0 1.4 1 1 0 1 1 1 0 ABC transporter TniB PF05621.11 KIY63944.1 - 0.14 11.6 0.0 0.27 10.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AAA_25 PF13481.6 KIY63944.1 - 0.15 11.6 0.1 1.6 8.3 0.0 2.2 2 1 0 2 2 2 0 AAA domain Phage_holin_5_2 PF16079.5 KIY63947.1 - 0.51 10.7 3.2 14 6.1 0.0 2.5 1 1 1 2 2 2 0 Phage holin family Hol44, in holin superfamily V DisA_N PF02457.16 KIY63950.1 - 0.062 12.9 0.0 0.083 12.5 0.0 1.3 1 0 0 1 1 1 0 DisA bacterial checkpoint controller nucleotide-binding WSN PF02206.18 KIY63950.1 - 0.26 11.2 0.1 0.41 10.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function Phage_holin_5_2 PF16079.5 KIY63953.1 - 0.23 11.8 2.1 8.3 6.8 0.0 2.5 1 1 1 2 2 2 0 Phage holin family Hol44, in holin superfamily V Alanine_zipper PF11839.8 KIY63960.1 - 0.015 15.7 8.3 0.015 15.7 8.3 2.2 1 1 1 2 2 2 0 Alanine-zipper, major outer membrane lipoprotein Flot PF15975.5 KIY63960.1 - 0.098 12.8 0.1 0.098 12.8 0.1 2.0 2 0 0 2 2 2 0 Flotillin Seryl_tRNA_N PF02403.22 KIY63960.1 - 0.36 11.1 6.0 0.52 10.6 6.0 1.2 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF4175 PF13779.6 KIY63960.1 - 0.49 8.2 14.0 0.64 7.9 14.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) T3SSipB PF16535.5 KIY63960.1 - 1 9.8 8.2 2.7 8.4 8.0 1.6 1 1 0 1 1 1 0 Type III cell invasion protein SipB OmpH PF03938.14 KIY63960.1 - 3.4 8.0 8.8 5 7.5 8.8 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF724 PF05266.14 KIY63960.1 - 3.6 7.4 7.8 5.6 6.8 7.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) LPP PF04728.13 KIY63960.1 - 9.5 6.7 10.3 1.7 9.1 1.9 2.7 2 1 0 2 2 2 0 Lipoprotein leucine-zipper Phage_holin_5_2 PF16079.5 KIY63961.1 - 0.076 13.4 1.4 9.2 6.7 0.1 2.5 2 0 0 2 2 2 0 Phage holin family Hol44, in holin superfamily V DDE_Tnp_1_6 PF13751.6 KIY63962.1 - 0.16 12.2 3.1 0.22 11.8 3.1 1.1 1 0 0 1 1 1 0 Transposase DDE domain Pmp3 PF01679.17 KIY63965.1 - 4.1e-22 78.1 9.2 4.5e-22 78.0 9.2 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Transferase PF02458.15 KIY63968.1 - 0.00098 17.9 0.0 0.035 12.8 0.0 2.5 3 0 0 3 3 3 2 Transferase family Transferase PF02458.15 KIY63969.1 - 5.4e-05 22.0 0.0 0.16 10.6 0.0 2.8 3 0 0 3 3 3 2 Transferase family Condensation PF00668.20 KIY63969.1 - 0.12 11.1 0.0 0.18 10.4 0.0 1.1 1 0 0 1 1 1 0 Condensation domain Transferase PF02458.15 KIY63970.1 - 4.1e-05 22.4 0.0 0.00033 19.5 0.0 2.1 2 1 0 2 2 2 1 Transferase family Citrate_bind PF16114.5 KIY63972.1 - 3.6e-89 297.0 0.1 6.6e-89 296.1 0.1 1.4 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding Citrate_synt PF00285.21 KIY63972.1 - 7.9e-18 64.7 0.1 2.7e-15 56.3 0.0 2.7 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain Ligase_CoA PF00549.19 KIY63972.1 - 5.8e-15 55.4 0.0 1.2e-14 54.4 0.0 1.6 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.19 KIY63972.1 - 5.5e-12 46.2 0.0 1.4e-11 44.9 0.0 1.8 1 0 0 1 1 1 1 CoA binding domain ATP-grasp_2 PF08442.10 KIY63972.1 - 4.3e-06 26.4 0.0 1.1e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.6 KIY63972.1 - 4.9e-05 23.2 0.0 0.00015 21.6 0.0 1.8 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain F-box-like PF12937.7 KIY63974.1 - 4.7e-10 39.2 0.3 1.3e-09 37.8 0.3 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY63974.1 - 0.045 13.6 2.1 0.16 11.9 0.2 2.7 2 1 0 2 2 2 0 F-box domain TAFII28 PF04719.14 KIY63976.1 - 6.1e-34 116.0 0.1 8.6e-34 115.5 0.1 1.2 1 0 0 1 1 1 1 hTAFII28-like protein conserved region CBFD_NFYB_HMF PF00808.23 KIY63976.1 - 0.00091 19.5 0.0 0.0015 18.8 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone NUDIX PF00293.28 KIY63980.1 - 6.1e-08 32.8 0.0 1.1e-07 31.9 0.0 1.4 1 1 0 1 1 1 1 NUDIX domain SfLAP PF11139.8 KIY63980.1 - 0.006 16.0 0.2 0.012 15.1 0.1 1.4 2 0 0 2 2 2 1 Sap, sulfolipid-1-addressing protein MFS_1 PF07690.16 KIY63981.1 - 3.8e-36 124.8 26.8 5.2e-36 124.3 26.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4381 PF14316.6 KIY63981.1 - 0.16 12.2 1.0 0.47 10.7 1.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF1656 PF07869.12 KIY63981.1 - 0.35 10.9 5.4 0.37 10.8 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1656) Glyco_hydro_88 PF07470.13 KIY63982.1 - 6.2e-26 91.3 0.2 8.5e-26 90.8 0.2 1.1 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Anoctamin PF04547.12 KIY63984.1 - 7.8e-100 334.8 1.6 9.2e-100 334.6 1.6 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel F-box-like PF12937.7 KIY63986.1 - 1.5e-08 34.4 0.2 2.4e-08 33.7 0.2 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY63986.1 - 5.4e-07 29.3 0.0 0.00049 19.9 0.0 2.3 2 0 0 2 2 2 2 F-box domain Glyco_hydro_79C PF16862.5 KIY63991.1 - 1.9e-18 67.2 0.0 9.2e-18 65.0 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolase family 79 C-terminal beta domain F-box-like PF12937.7 KIY63998.1 - 0.00028 20.7 0.1 0.0011 18.8 0.1 2.1 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.6 KIY63998.1 - 0.00029 20.6 0.9 0.0018 18.0 0.1 2.6 2 0 0 2 2 2 1 Leucine rich repeat Acetyltransf_10 PF13673.7 KIY64001.1 - 1.3e-07 31.5 0.0 1.9e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIY64001.1 - 5e-07 30.0 0.0 6.5e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KIY64001.1 - 2.3e-05 24.7 0.0 3.5e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIY64001.1 - 0.024 14.6 0.0 0.037 14.0 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_18 PF18014.1 KIY64001.1 - 0.18 11.6 0.0 0.3 10.9 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KIY64002.1 - 0.024 14.7 0.0 0.078 13.1 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain zf-MYND PF01753.18 KIY64003.1 - 1.2e-07 31.7 9.7 3.1e-07 30.4 9.7 1.8 1 0 0 1 1 1 1 MYND finger EIF4E-T PF10477.9 KIY64003.1 - 0.012 14.5 0.3 0.012 14.5 0.3 1.1 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E Spt20 PF12090.8 KIY64003.1 - 2.2 7.8 11.5 3 7.4 11.5 1.1 1 0 0 1 1 1 0 Spt20 family RRM_1 PF00076.22 KIY64004.1 - 5e-14 51.9 0.0 9.6e-14 51.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KIY64004.1 - 0.0031 17.5 0.0 0.0055 16.7 0.0 1.4 1 0 0 1 1 1 1 RNA binding motif Chromo_shadow PF01393.19 KIY64005.1 - 1.2e-12 47.7 0.2 3.1e-12 46.4 0.2 1.8 1 0 0 1 1 1 1 Chromo shadow domain Chromo PF00385.24 KIY64005.1 - 6.8e-11 41.9 1.4 1.2e-10 41.1 0.2 2.1 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain PNK3P PF08645.11 KIY64005.1 - 0.043 13.5 0.0 0.078 12.7 0.0 1.5 1 0 0 1 1 1 0 Polynucleotide kinase 3 phosphatase Dicty_REP PF05086.12 KIY64005.1 - 1.4 6.8 9.8 2 6.3 9.8 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SAPS PF04499.15 KIY64005.1 - 3.3 6.4 10.0 3.7 6.2 10.0 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein ORC6 PF05460.13 KIY64005.1 - 4 6.6 17.2 0.063 12.5 10.5 1.4 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) NPR3 PF03666.13 KIY64005.1 - 4.4 6.0 14.2 7 5.3 14.2 1.4 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SLC12 PF03522.15 KIY64005.1 - 7.4 5.5 9.8 10 5.0 9.8 1.2 1 0 0 1 1 1 0 Solute carrier family 12 DUF4551 PF15087.6 KIY64005.1 - 8 5.2 8.5 10 4.8 8.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Hid1 PF12722.7 KIY64005.1 - 8.4 4.4 12.4 9.5 4.2 12.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein ALMT PF11744.8 KIY64005.1 - 8.5 5.1 9.0 11 4.7 9.0 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter RTC4 PF14474.6 KIY64007.1 - 7.2e-27 94.0 0.0 9.4e-27 93.6 0.0 1.2 1 0 0 1 1 1 1 RTC4-like domain AICARFT_IMPCHas PF01808.18 KIY64009.1 - 5.7e-87 291.9 0.0 7.5e-87 291.5 0.0 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 KIY64009.1 - 1.2e-23 83.0 0.0 2.4e-23 82.1 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain Ribosomal_L12_N PF16320.5 KIY64009.1 - 0.23 11.2 1.2 0.54 10.0 1.2 1.5 1 0 0 1 1 1 0 Ribosomal protein L7/L12 dimerisation domain F-box-like PF12937.7 KIY64010.1 - 1.8e-08 34.1 1.3 7.9e-08 32.1 1.3 1.9 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KIY64010.1 - 0.034 14.0 2.5 1.7 8.6 1.3 2.5 2 0 0 2 2 2 0 F-box domain Glutaredoxin PF00462.24 KIY64012.1 - 7.6e-17 61.3 0.0 1.3e-16 60.5 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin NAD_binding_4 PF07993.12 KIY64013.1 - 1.8e-31 109.3 0.0 2.5e-31 108.8 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 KIY64013.1 - 2.4e-10 40.3 0.0 5.6e-10 39.1 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KIY64013.1 - 2.4e-09 37.4 0.0 6.7e-09 36.0 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site KR PF08659.10 KIY64013.1 - 0.00027 20.9 0.1 0.00054 19.9 0.1 1.5 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KIY64013.1 - 0.013 14.7 0.0 0.021 14.0 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.24 KIY64013.1 - 0.014 15.9 0.2 0.1 13.1 0.0 2.2 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Solute_trans_a PF03619.16 KIY64014.1 - 4.9e-64 216.4 20.8 6e-64 216.1 20.8 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha GtrA PF04138.14 KIY64014.1 - 7.5 6.8 13.4 0.15 12.3 0.7 2.8 2 1 0 2 2 2 0 GtrA-like protein CsbD PF05532.12 KIY64016.1 - 2.9e-16 59.1 4.9 2.7e-10 40.0 0.7 2.1 1 1 1 2 2 2 2 CsbD-like RhoGAP PF00620.27 KIY64018.1 - 8.5e-35 119.8 0.0 1.6e-34 119.0 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 KIY64018.1 - 2.6e-26 91.6 38.0 2.7e-10 40.3 7.7 4.6 4 0 0 4 4 4 4 LIM domain Pribosyltran_N PF13793.6 KIY64020.1 - 4.9e-50 168.3 0.3 2.1e-49 166.3 0.0 2.1 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 KIY64020.1 - 1e-37 130.0 2.0 5.1e-34 117.9 0.9 2.5 2 1 1 3 3 3 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 KIY64020.1 - 1.3e-15 57.3 1.4 4.9e-14 52.2 0.7 2.3 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KIY64020.1 - 4.2e-05 23.1 0.1 8.2e-05 22.1 0.1 1.5 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase OCD_Mu_crystall PF02423.15 KIY64020.1 - 0.062 12.2 1.2 0.49 9.3 0.2 2.4 2 1 1 3 3 3 0 Ornithine cyclodeaminase/mu-crystallin family ParA PF10609.9 KIY64021.1 - 1.1e-96 323.1 0.0 1.3e-96 322.9 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KIY64021.1 - 1e-09 38.5 0.0 1.5e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 KIY64021.1 - 1.5e-05 24.4 1.2 0.00087 18.6 0.1 2.8 2 1 1 3 3 3 1 Anion-transporting ATPase AAA_31 PF13614.6 KIY64021.1 - 0.0002 21.3 0.1 0.0013 18.6 0.1 2.0 1 1 0 1 1 1 1 AAA domain CBP_BcsQ PF06564.12 KIY64021.1 - 0.0016 18.0 0.0 0.0057 16.2 0.0 1.8 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ Fer4_NifH PF00142.18 KIY64021.1 - 0.004 16.7 0.0 0.48 9.8 0.0 2.6 2 1 1 3 3 3 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_25 PF13481.6 KIY64021.1 - 0.0053 16.3 0.0 0.0096 15.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_26 PF13500.6 KIY64021.1 - 0.0073 16.1 0.0 0.096 12.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KIY64021.1 - 0.013 15.4 0.0 0.027 14.4 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase NB-ARC PF00931.22 KIY64021.1 - 0.065 12.4 0.1 0.1 11.7 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.22 KIY64021.1 - 0.14 12.6 0.0 0.45 10.9 0.0 1.8 2 0 0 2 2 2 0 RNA helicase MipZ PF09140.11 KIY64021.1 - 0.17 11.2 0.0 0.44 9.8 0.0 1.7 1 1 0 1 1 1 0 ATPase MipZ NACHT PF05729.12 KIY64021.1 - 0.21 11.5 0.2 0.33 10.8 0.2 1.3 1 0 0 1 1 1 0 NACHT domain Pkinase PF00069.25 KIY64022.1 - 0.021 14.2 0.0 0.23 10.8 0.0 2.0 2 0 0 2 2 2 0 Protein kinase domain CsbD PF05532.12 KIY64023.1 - 2.1e-13 49.9 8.8 2.7e-08 33.6 1.1 2.2 1 1 1 2 2 2 2 CsbD-like RNase_H PF00075.24 KIY64024.1 - 1.3e-19 70.8 0.1 2.8e-19 69.7 0.1 1.6 1 1 0 1 1 1 1 RNase H RVT_3 PF13456.6 KIY64024.1 - 2.9e-07 30.3 0.1 0.0052 16.6 0.0 3.4 2 2 2 4 4 4 2 Reverse transcriptase-like DUF4259 PF14078.6 KIY64025.1 - 0.038 14.7 0.0 0.066 14.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4259) RNase_H PF00075.24 KIY64026.1 - 2.9e-19 69.7 0.0 6.7e-19 68.5 0.0 1.6 1 1 0 1 1 1 1 RNase H RVT_3 PF13456.6 KIY64026.1 - 0.00028 20.7 0.0 0.15 11.9 0.0 2.7 3 0 0 3 3 3 2 Reverse transcriptase-like Rad4 PF03835.15 KIY64026.1 - 0.047 13.4 0.1 0.069 12.8 0.1 1.3 1 0 0 1 1 1 0 Rad4 transglutaminase-like domain Nup54 PF13874.6 KIY64027.1 - 1.1e-34 119.6 3.6 2.3e-34 118.5 3.6 1.5 1 0 0 1 1 1 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.6 KIY64027.1 - 5.3e-26 91.3 153.4 4.7e-10 40.2 43.0 5.6 1 1 4 5 5 5 5 Nucleoporin FG repeat region Nup54_C PF18437.1 KIY64027.1 - 6.3e-05 22.8 0.3 6.3e-05 22.8 0.3 1.9 2 0 0 2 2 2 1 Nup54 C-terminal interacting domain NAD_binding_10 PF13460.6 KIY64027.1 - 0.046 13.6 0.1 0.082 12.8 0.1 1.3 1 0 0 1 1 1 0 NAD(P)H-binding BAR PF03114.18 KIY64027.1 - 0.085 12.5 0.3 0.18 11.4 0.3 1.5 1 0 0 1 1 1 0 BAR domain Focal_AT PF03623.13 KIY64027.1 - 0.16 11.9 0.7 0.31 11.0 0.7 1.4 1 0 0 1 1 1 0 Focal adhesion targeting region Acetyltransf_3 PF13302.7 KIY64028.1 - 4.1e-11 43.7 0.0 5.7e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIY64028.1 - 0.0038 17.5 0.0 0.0052 17.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family P22_Cro PF14549.6 KIY64028.1 - 0.031 14.1 0.1 0.069 13.0 0.1 1.5 1 0 0 1 1 1 0 DNA-binding transcriptional regulator Cro 2OG-FeII_Oxy_3 PF13640.6 KIY64030.1 - 1.8e-09 38.4 0.0 2.7e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 KIY64030.1 - 0.064 13.9 0.0 0.11 13.2 0.0 1.3 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Symplekin_C PF12295.8 KIY64034.1 - 2.8e-63 213.4 0.9 8.8e-63 211.8 0.9 1.9 1 0 0 1 1 1 1 Symplekin tight junction protein C terminal DUF3453 PF11935.8 KIY64034.1 - 1.5e-44 152.3 1.8 5e-43 147.3 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3453) HEAT_2 PF13646.6 KIY64034.1 - 0.0011 19.4 1.4 0.82 10.1 0.5 3.8 2 1 1 3 3 3 1 HEAT repeats HEAT PF02985.22 KIY64034.1 - 0.0094 16.1 0.1 12 6.5 0.0 3.2 2 0 0 2 2 2 2 HEAT repeat Arm PF00514.23 KIY64034.1 - 0.041 13.9 1.6 5.7 7.1 0.1 3.8 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KIY64034.1 - 0.33 11.5 3.8 11 6.6 0.1 4.3 4 0 0 4 4 4 0 HEAT-like repeat V-ATPase_G PF03179.15 KIY64035.1 - 9.8e-35 119.3 14.9 1.1e-34 119.1 14.9 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit DUF3552 PF12072.8 KIY64035.1 - 0.018 14.4 9.8 0.018 14.4 9.8 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) ATP-synt_B PF00430.18 KIY64035.1 - 0.24 11.5 16.2 0.087 12.9 12.4 1.9 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) DUF4358 PF14270.6 KIY64035.1 - 0.25 11.6 7.9 0.31 11.4 4.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4358) V-ATPase_G_2 PF16999.5 KIY64035.1 - 0.28 11.6 14.5 1 9.8 14.5 1.9 1 1 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit Mersacidin PF16934.5 KIY64038.1 - 0.066 13.0 0.1 0.62 9.9 0.1 2.3 2 0 0 2 2 2 0 Two-component Enterococcus faecalis cytolysin (EFC) Zn_ribbon_17 PF17120.5 KIY64038.1 - 0.11 12.1 0.5 0.22 11.2 0.5 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Zn_ribbon_17 PF17120.5 KIY64039.1 - 0.082 12.5 0.5 0.15 11.7 0.5 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type tRNA_U5-meth_tr PF05958.11 KIY64039.1 - 0.13 11.2 0.0 0.19 10.7 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase zf-C3H2C3 PF17122.5 KIY64039.1 - 0.19 11.8 1.6 0.42 10.7 1.6 1.5 1 0 0 1 1 1 0 Zinc-finger GTA_holin_3TM PF11351.8 KIY64040.1 - 0.33 11.5 0.1 0.33 11.5 0.1 1.5 2 0 0 2 2 2 0 Holin of 3TMs, for gene-transfer release SWIRM PF04433.17 KIY64041.1 - 2.9e-31 107.6 0.0 6e-30 103.4 0.1 2.5 2 0 0 2 2 2 1 SWIRM domain SWIRM-assoc_1 PF16495.5 KIY64041.1 - 1e-20 73.5 12.1 2.5e-20 72.2 12.1 1.7 1 0 0 1 1 1 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 KIY64041.1 - 1.5e-08 34.7 1.0 2.8e-08 33.8 0.1 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KIY64041.1 - 4.2e-06 26.9 0.0 9.8e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.17 KIY64041.1 - 3.6e-05 23.5 2.6 6.7e-05 22.6 2.6 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type Blt1 PF12754.7 KIY64041.1 - 0.0089 16.3 0.7 0.022 15.1 0.7 1.7 1 0 0 1 1 1 1 Blt1 N-terminal domain Methyltransf_32 PF13679.6 KIY64041.1 - 0.087 12.8 0.1 0.25 11.3 0.1 1.7 1 0 0 1 1 1 0 Methyltransferase domain HTH_37 PF13744.6 KIY64041.1 - 0.19 11.7 4.6 0.13 12.2 1.5 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain Pex19 PF04614.12 KIY64042.1 - 4.3e-56 190.4 9.1 5.2e-56 190.2 9.1 1.0 1 0 0 1 1 1 1 Pex19 protein family UPF0270 PF06794.12 KIY64042.1 - 0.066 13.3 0.1 0.56 10.3 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0270) Ccdc124 PF06244.12 KIY64042.1 - 0.098 13.2 0.8 0.17 12.4 0.1 1.8 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 124 /Oxs1 IF2_N PF04760.15 KIY64042.1 - 0.1 12.4 0.4 0.1 12.4 0.4 2.1 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region p450 PF00067.22 KIY64043.1 - 6.7e-70 236.1 0.0 8.1e-70 235.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MMtag PF10159.9 KIY64045.1 - 6.5e-31 106.4 2.5 6.5e-31 106.4 2.5 2.5 2 1 0 2 2 2 1 Multiple myeloma tumor-associated DUF4407 PF14362.6 KIY64045.1 - 3.5 6.9 9.9 4.5 6.5 9.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SelP_N PF04592.14 KIY64045.1 - 3.9 6.8 12.5 6.6 6.1 12.5 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region RR_TM4-6 PF06459.12 KIY64045.1 - 4.8 6.9 14.1 6.1 6.6 14.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NARP1 PF12569.8 KIY64045.1 - 5.7 5.7 13.0 9.3 5.0 13.0 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 GREB1 PF15782.5 KIY64045.1 - 8.2 3.4 7.6 9.5 3.2 7.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer WD40 PF00400.32 KIY64047.1 - 1.2e-05 26.0 14.3 0.0038 18.0 0.0 5.6 6 1 0 6 6 6 2 WD domain, G-beta repeat Zn_ribbon_17 PF17120.5 KIY64047.1 - 2.4e-05 23.9 5.8 2.4e-05 23.9 5.8 2.8 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type PHD PF00628.29 KIY64047.1 - 0.0099 15.8 10.3 0.022 14.6 3.8 2.5 2 0 0 2 2 2 1 PHD-finger Prok-RING_1 PF14446.6 KIY64047.1 - 0.83 9.6 4.7 2.2 8.3 4.7 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 DNA_pol_phi PF04931.13 KIY64047.1 - 1.4 6.9 8.3 2.5 6.1 8.3 1.3 1 0 0 1 1 1 0 DNA polymerase phi Zf_RING PF16744.5 KIY64047.1 - 2.7 8.2 7.0 2.1 8.5 4.7 2.0 1 1 1 2 2 2 0 KIAA1045 RING finger zf-LSD1 PF06943.12 KIY64047.1 - 9.3 6.2 13.7 0.41 10.5 0.5 3.5 3 0 0 3 3 3 0 LSD1 zinc finger DUF1295 PF06966.12 KIY64048.1 - 2.8e-45 154.7 0.2 3.8e-45 154.2 0.2 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 KIY64048.1 - 0.0012 19.2 0.0 0.0033 17.8 0.0 1.8 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KIY64048.1 - 0.012 16.0 0.0 0.033 14.6 0.0 1.7 1 0 0 1 1 1 0 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 KIY64048.1 - 0.021 13.6 0.3 0.033 13.0 0.3 1.3 1 0 0 1 1 1 0 Ergosterol biosynthesis ERG4/ERG24 family Steroid_dh PF02544.16 KIY64048.1 - 0.084 12.9 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 3-oxo-5-alpha-steroid 4-dehydrogenase DUF2976 PF11190.8 KIY64048.1 - 0.12 12.2 0.8 19 5.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) HAMP PF00672.25 KIY64049.1 - 1.5e-45 153.4 14.8 9.2e-08 32.4 0.1 8.1 7 0 0 7 7 7 7 HAMP domain HATPase_c PF02518.26 KIY64049.1 - 3.2e-30 104.9 0.1 8.7e-30 103.5 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KIY64049.1 - 1.1e-23 83.5 0.1 1.1e-23 83.5 0.1 2.4 3 0 0 3 3 3 1 Response regulator receiver domain HisKA PF00512.25 KIY64049.1 - 2.9e-16 59.3 3.7 3.2e-16 59.1 1.1 2.7 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain APG17 PF04108.12 KIY64049.1 - 9.9e-05 21.6 4.4 0.2 10.8 0.6 4.0 3 1 1 4 4 4 2 Autophagy protein Apg17 DUF3829 PF12889.7 KIY64049.1 - 0.00094 18.7 6.9 0.073 12.5 0.5 4.3 4 1 0 5 5 5 2 Protein of unknown function (DUF3829) Secretin_N_2 PF07655.13 KIY64049.1 - 0.17 12.4 1.2 3 8.4 0.0 3.8 4 0 0 4 4 4 0 Secretin N-terminal domain RAP-1 PF03085.15 KIY64049.1 - 8.1 6.1 15.3 11 5.6 0.2 4.3 4 0 0 4 4 4 0 Rhoptry-associated protein 1 (RAP-1) MARVEL PF01284.23 KIY64050.1 - 7.3e-10 39.0 10.6 7.3e-10 39.0 10.6 1.6 2 0 0 2 2 2 1 Membrane-associating domain Ni_hydr_CYTB PF01292.20 KIY64050.1 - 0.074 12.6 6.7 0.48 10.0 4.9 2.2 2 0 0 2 2 2 0 Prokaryotic cytochrome b561 7tm_1 PF00001.21 KIY64050.1 - 2 7.7 6.8 0.18 11.1 1.7 1.7 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) ATG27 PF09451.10 KIY64050.1 - 2.8 7.7 4.0 4.5 7.0 0.6 2.1 2 0 0 2 2 2 0 Autophagy-related protein 27 Dus PF01207.17 KIY64051.1 - 4.8e-58 196.7 0.0 5.6e-58 196.5 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 KIY64051.1 - 0.038 13.4 0.0 0.063 12.7 0.0 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein IMPDH PF00478.25 KIY64051.1 - 0.19 10.7 0.0 0.26 10.2 0.0 1.1 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain Aldolase_II PF00596.21 KIY64052.1 - 1.9e-40 138.8 0.0 2.3e-40 138.5 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain RicinB_lectin_2 PF14200.6 KIY64053.1 - 8e-23 81.0 9.7 3.1e-09 37.4 0.1 2.4 1 1 2 3 3 3 3 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 KIY64053.1 - 6.9e-20 71.6 3.3 2.2e-19 70.0 3.6 1.6 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Hira PF07569.11 KIY64054.1 - 3.9e-53 180.5 0.0 7.5e-53 179.5 0.0 1.5 1 0 0 1 1 1 1 TUP1-like enhancer of split WD40 PF00400.32 KIY64054.1 - 2.6e-30 104.0 14.6 5e-07 30.3 0.5 8.2 8 0 0 8 8 8 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY64054.1 - 2.9e-13 49.9 1.0 0.03 14.6 0.0 6.0 2 1 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 KIY64054.1 - 0.045 14.3 3.6 29 5.3 0.0 4.3 4 0 0 4 4 4 0 PQQ-like domain NAD_binding_6 PF08030.12 KIY64057.1 - 7.3e-26 91.2 0.0 1.4e-25 90.2 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 KIY64057.1 - 2.2e-19 69.8 8.6 6.3e-19 68.3 8.6 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KIY64057.1 - 3.1e-14 53.0 0.0 5.5e-10 39.3 0.0 2.5 2 0 0 2 2 2 2 FAD-binding domain Fungal_trans PF04082.18 KIY64058.1 - 2.5e-21 75.9 0.0 3.7e-21 75.3 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY64058.1 - 3.4e-10 39.9 11.5 7.6e-10 38.8 11.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-RING_9 PF13901.6 KIY64059.1 - 0.031 14.3 0.6 0.031 14.3 0.6 1.7 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon Suf PF05843.14 KIY64059.1 - 0.95 9.4 6.4 2 8.4 6.4 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) RTA1 PF04479.13 KIY64060.1 - 3.9e-62 209.5 6.9 4.9e-62 209.2 6.9 1.1 1 0 0 1 1 1 1 RTA1 like protein zf-4CXXC_R1 PF10497.9 KIY64061.1 - 3.3e-06 27.3 14.9 6.5e-06 26.3 14.9 1.4 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 GPI-anchored PF10342.9 KIY64064.1 - 9.4e-08 32.7 0.1 9.4e-08 32.7 0.1 2.1 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Sporozoite_P67 PF05642.11 KIY64064.1 - 0.0035 15.5 5.8 0.0033 15.6 5.8 1.1 1 0 0 1 1 1 1 Sporozoite P67 surface antigen Menin PF05053.13 KIY64064.1 - 0.26 9.6 1.6 0.31 9.4 1.6 1.1 1 0 0 1 1 1 0 Menin DUF515 PF04415.12 KIY64064.1 - 7.2 4.9 12.5 9.8 4.4 12.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Mito_carr PF00153.27 KIY64066.1 - 5.8e-55 183.2 1.2 1.9e-17 63.0 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein Ricin_B_lectin PF00652.22 KIY64068.1 - 8.8e-32 110.0 20.6 5e-21 75.3 6.9 2.3 1 1 2 3 3 3 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KIY64068.1 - 4.2e-20 72.3 22.0 8e-11 42.5 3.9 3.6 1 1 2 3 3 3 3 Ricin-type beta-trefoil lectin domain-like LysM PF01476.20 KIY64069.1 - 4.9e-10 39.3 0.0 6.6e-05 22.9 0.0 2.2 2 0 0 2 2 2 2 LysM domain SLAC1 PF03595.17 KIY64070.1 - 1.8e-64 218.1 39.6 2.1e-64 217.8 39.6 1.1 1 0 0 1 1 1 1 Voltage-dependent anion channel G-alpha PF00503.20 KIY64071.1 - 1.1e-120 403.1 0.8 1.3e-120 402.8 0.8 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KIY64071.1 - 1.4e-16 60.4 1.0 1.1e-11 44.5 0.0 2.7 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KIY64071.1 - 6.4e-05 22.4 1.2 0.0035 16.7 0.0 2.5 2 1 0 2 2 2 1 Gtr1/RagA G protein conserved region Roc PF08477.13 KIY64071.1 - 0.0034 17.6 0.3 2.9 8.2 0.0 2.7 3 0 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 KIY64071.1 - 0.026 14.1 0.0 7 6.1 0.0 2.4 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain zf-CHC2 PF01807.20 KIY64071.1 - 0.033 14.0 0.0 0.13 12.1 0.0 1.9 2 0 0 2 2 2 0 CHC2 zinc finger AAA_29 PF13555.6 KIY64071.1 - 0.04 13.7 0.0 0.11 12.2 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KIY64071.1 - 0.067 13.3 0.0 2.5 8.2 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 KIY64071.1 - 0.082 12.2 0.1 0.21 10.9 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family NAD_binding_10 PF13460.6 KIY64072.1 - 1.8e-08 34.5 0.2 2.8e-08 33.9 0.2 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KIY64072.1 - 4.6e-08 32.8 0.0 6.2e-07 29.1 0.0 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KIY64072.1 - 6.2e-08 32.5 0.2 1.1e-07 31.7 0.2 1.4 1 0 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 KIY64072.1 - 3e-07 30.7 0.4 5.8e-07 29.8 0.3 1.5 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_4 PF07993.12 KIY64072.1 - 2.8e-06 26.7 0.1 0.0012 18.1 0.1 2.2 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.19 KIY64072.1 - 0.00041 19.4 0.3 0.00069 18.7 0.3 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.20 KIY64072.1 - 0.00069 19.7 0.1 0.0012 18.9 0.1 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 KIY64072.1 - 0.0031 17.9 0.0 0.0055 17.1 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KIY64072.1 - 0.02 14.9 0.0 0.032 14.3 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DXP_reductoisom PF02670.16 KIY64072.1 - 0.069 13.9 0.1 0.13 12.9 0.1 1.5 1 1 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase F-box-like PF12937.7 KIY64073.1 - 0.0018 18.2 0.2 0.0041 17.0 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY64073.1 - 0.064 13.2 0.1 0.16 11.9 0.1 1.7 1 0 0 1 1 1 0 F-box domain F-box PF00646.33 KIY64074.1 - 6.3e-06 25.9 0.6 1.6e-05 24.7 0.6 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KIY64074.1 - 0.00014 21.7 0.8 0.00031 20.6 0.8 1.6 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KIY64074.1 - 0.00061 19.7 0.8 0.0022 17.9 0.1 2.0 2 0 0 2 2 2 1 F-box F-box-like_2 PF13013.6 KIY64074.1 - 1.8 8.6 5.4 20 5.2 0.1 3.6 3 1 1 4 4 4 0 F-box-like domain HI0933_like PF03486.14 KIY64075.1 - 0.23 10.1 0.0 0.34 9.6 0.0 1.1 1 0 0 1 1 1 0 HI0933-like protein Sugar_tr PF00083.24 KIY64080.1 - 6.8e-111 371.3 19.9 7.9e-111 371.1 19.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY64080.1 - 8.7e-23 80.8 31.0 7e-17 61.4 10.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KIY64080.1 - 0.00027 19.4 2.8 0.014 13.8 0.7 2.3 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family Transketolase_N PF00456.21 KIY64081.1 - 1.1e-125 419.1 0.1 1.5e-125 418.6 0.1 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 KIY64081.1 - 7.6e-40 136.5 0.0 1.3e-39 135.7 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KIY64081.1 - 1e-08 35.1 0.0 2.9e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 KIY64081.1 - 1.2e-08 34.5 0.0 2.9e-07 30.0 0.0 2.2 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 KIY64081.1 - 3e-05 23.8 1.0 0.00011 22.1 1.0 1.9 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.20 KIY64081.1 - 0.026 13.5 0.8 0.042 12.8 0.8 1.2 1 0 0 1 1 1 0 Dehydrogenase E1 component XFP_C PF09363.10 KIY64081.1 - 0.22 11.0 0.0 0.39 10.1 0.0 1.3 1 0 0 1 1 1 0 XFP C-terminal domain adh_short_C2 PF13561.6 KIY64082.1 - 2.7e-53 180.9 0.1 3.6e-53 180.5 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIY64082.1 - 1e-42 145.9 1.0 1.2e-42 145.6 1.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIY64082.1 - 2.3e-14 53.7 0.3 3.1e-14 53.3 0.3 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KIY64082.1 - 0.00013 21.5 0.1 0.00025 20.6 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KIY64082.1 - 0.0048 16.0 0.0 0.0072 15.4 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Fungal_trans PF04082.18 KIY64083.1 - 1.5e-22 79.9 0.0 2.3e-22 79.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY64083.1 - 4.8e-05 23.4 18.9 0.00015 21.8 18.9 1.8 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dak1 PF02733.17 KIY64086.1 - 1.7e-97 326.1 2.3 2.3e-97 325.7 2.3 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 KIY64086.1 - 3.2e-38 131.3 2.7 5.2e-38 130.7 2.7 1.3 1 0 0 1 1 1 1 DAK2 domain BMC PF00936.19 KIY64086.1 - 8.6 6.4 13.5 0.13 12.2 3.1 3.0 3 0 0 3 3 3 0 BMC domain Suf PF05843.14 KIY64087.1 - 0.34 10.9 10.2 0.67 9.9 10.2 1.5 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Borrelia_P83 PF05262.11 KIY64087.1 - 0.39 9.2 15.5 0.55 8.7 15.5 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein RR_TM4-6 PF06459.12 KIY64087.1 - 2.9 7.6 18.8 6.2 6.6 18.8 1.6 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Vfa1 PF08432.10 KIY64087.1 - 4.3 7.6 23.0 12 6.2 23.0 1.7 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 TMEM247 PF15444.6 KIY64087.1 - 5.5 7.0 11.1 12 5.9 11.1 1.5 1 0 0 1 1 1 0 Transmembrane protein 247 DUF1279 PF06916.13 KIY64088.1 - 2e-18 66.7 0.0 2.7e-18 66.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) DUF3325 PF11804.8 KIY64088.1 - 2.3 8.4 10.1 0.34 11.1 2.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3325) DUF1604 PF07713.13 KIY64089.1 - 4.9e-38 128.8 1.0 4.9e-38 128.8 1.0 3.0 4 0 0 4 4 4 1 Protein of unknown function (DUF1604) G-patch PF01585.23 KIY64089.1 - 3.7e-05 23.5 0.2 3.7e-05 23.5 0.2 2.4 3 0 0 3 3 3 1 G-patch domain G-patch_2 PF12656.7 KIY64089.1 - 0.11 12.7 0.7 0.56 10.3 0.1 2.6 2 0 0 2 2 2 0 G-patch domain RPEL PF02755.15 KIY64090.1 - 1.7e-13 49.7 8.5 3e-06 26.7 3.0 2.6 2 0 0 2 2 2 2 RPEL repeat AF-4 PF05110.13 KIY64090.1 - 0.017 13.2 13.3 0.016 13.3 13.3 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Corona_nucleoca PF00937.18 KIY64090.1 - 0.3 10.1 9.6 0.43 9.6 9.6 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Apt1 PF10351.9 KIY64090.1 - 1.6 7.5 5.7 2.1 7.1 5.7 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Steroid_dh PF02544.16 KIY64091.1 - 6.7e-28 97.6 4.5 1.8e-18 67.0 0.4 2.7 2 1 0 2 2 2 2 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 KIY64091.1 - 1.7e-06 27.7 0.6 3.8e-06 26.6 0.6 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) ABC_membrane PF00664.23 KIY64092.1 - 4e-47 161.2 24.5 1.2e-23 84.2 11.8 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KIY64092.1 - 4.6e-42 143.8 0.0 9.7e-26 90.9 0.1 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KIY64092.1 - 8.5e-12 45.0 3.0 0.0096 15.4 1.6 4.2 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KIY64092.1 - 5.2e-06 27.1 3.1 0.00046 20.7 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_25 PF13481.6 KIY64092.1 - 5.7e-06 26.0 0.1 0.024 14.2 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 KIY64092.1 - 1.2e-05 25.8 0.4 0.21 12.0 0.2 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 KIY64092.1 - 5.5e-05 22.8 0.8 0.15 11.9 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KIY64092.1 - 8.7e-05 22.8 0.1 1 9.6 0.1 3.3 2 1 0 2 2 2 2 AAA domain T2SSE PF00437.20 KIY64092.1 - 0.00022 20.4 0.0 0.54 9.3 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_21 PF13304.6 KIY64092.1 - 0.00059 19.7 3.1 0.7 9.6 0.0 4.1 2 2 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 KIY64092.1 - 0.00062 19.8 0.0 0.45 10.6 0.0 3.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIY64092.1 - 0.0015 18.5 0.0 1.3 8.9 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase Adeno_IVa2 PF02456.15 KIY64092.1 - 0.0019 17.1 0.0 0.15 10.8 0.0 2.5 2 0 0 2 2 2 1 Adenovirus IVa2 protein AAA_5 PF07728.14 KIY64092.1 - 0.002 18.1 0.4 4.5 7.3 0.0 4.1 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 KIY64092.1 - 0.0038 16.8 0.0 0.96 8.9 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA PF00004.29 KIY64092.1 - 0.0043 17.5 0.1 0.19 12.2 0.0 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.17 KIY64092.1 - 0.007 16.5 0.0 0.15 12.1 0.0 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_30 PF13604.6 KIY64092.1 - 0.025 14.3 0.1 6.7 6.4 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 KIY64092.1 - 0.026 14.3 0.0 0.9 9.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 KIY64092.1 - 0.033 13.6 0.0 7.3 5.9 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_11 PF13086.6 KIY64092.1 - 0.034 13.9 0.0 0.24 11.2 0.0 2.2 3 0 0 3 3 2 0 AAA domain TrwB_AAD_bind PF10412.9 KIY64092.1 - 0.036 13.0 0.4 3.7 6.3 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain RNA_helicase PF00910.22 KIY64092.1 - 0.047 14.1 0.0 3.8 7.9 0.0 2.6 2 0 0 2 2 2 0 RNA helicase IstB_IS21 PF01695.17 KIY64092.1 - 0.068 12.9 0.0 18 5.0 0.0 2.7 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_15 PF13175.6 KIY64092.1 - 0.072 12.8 0.0 0.97 9.1 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain ATP-synt_ab PF00006.25 KIY64092.1 - 0.08 12.6 0.0 11 5.6 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_33 PF13671.6 KIY64092.1 - 0.12 12.5 0.0 6.7 6.9 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 KIY64092.1 - 0.18 12.4 0.2 32 5.1 0.0 3.3 3 1 0 3 3 2 0 AAA domain PduV-EutP PF10662.9 KIY64092.1 - 0.21 11.3 0.4 7.5 6.3 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Rax2 PF12768.7 KIY64094.1 - 2.7e-45 154.5 3.7 1.3e-43 149.0 0.4 3.9 3 1 1 4 4 4 1 Cortical protein marker for cell polarity SH3_1 PF00018.28 KIY64094.1 - 2.9e-10 39.6 0.0 7e-10 38.4 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KIY64094.1 - 3.3e-07 30.1 0.1 1e-06 28.5 0.1 2.0 1 0 0 1 1 1 1 Variant SH3 domain Kelch_6 PF13964.6 KIY64094.1 - 0.0022 18.2 14.5 0.37 11.1 0.0 7.4 7 0 0 7 7 7 1 Kelch motif WD40_like PF17005.5 KIY64094.1 - 0.036 13.4 0.1 0.077 12.3 0.1 1.5 1 0 0 1 1 1 0 WD40-like domain Reg_prop PF07494.11 KIY64094.1 - 0.35 11.2 3.2 2.4 8.6 0.1 4.1 4 0 0 4 4 4 0 Two component regulator propeller Kelch_4 PF13418.6 KIY64094.1 - 1.5 8.9 8.1 0.85 9.7 0.2 4.7 4 0 0 4 4 4 0 Galactose oxidase, central domain ABC_tran PF00005.27 KIY64095.1 - 7e-30 104.3 0.1 2e-15 57.5 0.0 3.1 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KIY64095.1 - 2.3e-10 40.8 5.9 0.038 13.8 0.0 4.2 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KIY64095.1 - 7.9e-10 38.5 6.0 0.0015 18.0 0.0 4.0 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA PF00004.29 KIY64095.1 - 2.1e-05 25.0 0.0 0.21 12.0 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KIY64095.1 - 3.1e-05 24.4 0.0 0.11 12.9 0.0 2.6 2 1 0 2 2 2 2 AAA ATPase domain SbcCD_C PF13558.6 KIY64095.1 - 5e-05 23.4 0.0 0.25 11.6 0.0 2.6 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.6 KIY64095.1 - 9.4e-05 22.3 1.1 0.34 10.6 0.6 2.5 2 1 0 2 2 2 2 AAA ATPase domain NACHT PF05729.12 KIY64095.1 - 0.0001 22.3 0.9 0.037 13.9 0.0 2.5 2 0 0 2 2 2 1 NACHT domain RsgA_GTPase PF03193.16 KIY64095.1 - 0.00021 21.2 0.5 0.35 10.8 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_33 PF13671.6 KIY64095.1 - 0.00067 19.8 0.0 0.44 10.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KIY64095.1 - 0.00072 19.8 0.0 0.37 11.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 KIY64095.1 - 0.001 19.0 0.0 0.17 11.8 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain RNA_helicase PF00910.22 KIY64095.1 - 0.0012 19.2 0.0 1.5 9.3 0.0 2.7 2 0 0 2 2 2 1 RNA helicase SRP54 PF00448.22 KIY64095.1 - 0.0014 18.3 2.1 0.27 10.8 0.0 2.2 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain AAA_24 PF13479.6 KIY64095.1 - 0.0018 18.0 0.1 0.53 10.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KIY64095.1 - 0.0054 16.5 1.7 1.4 8.8 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.6 KIY64095.1 - 0.0054 17.3 0.2 1.3 9.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain Thymidylate_kin PF02223.17 KIY64095.1 - 0.0088 15.7 0.1 3.3 7.4 0.0 3.1 3 0 0 3 3 3 1 Thymidylate kinase AAA_5 PF07728.14 KIY64095.1 - 0.0096 15.9 1.8 0.22 11.5 0.1 2.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 KIY64095.1 - 0.01 15.6 0.6 0.91 9.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KIY64095.1 - 0.01 15.0 0.0 0.37 9.9 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_28 PF13521.6 KIY64095.1 - 0.012 15.9 0.6 2.7 8.2 0.1 2.4 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 KIY64095.1 - 0.032 14.2 1.6 0.16 12.0 0.1 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_13 PF13166.6 KIY64095.1 - 0.055 12.1 2.6 0.3 9.7 0.0 2.4 3 0 0 3 3 2 0 AAA domain AAA_7 PF12775.7 KIY64095.1 - 0.063 12.8 2.9 0.3 10.6 0.0 2.7 3 0 0 3 3 3 0 P-loop containing dynein motor region AAA_23 PF13476.6 KIY64095.1 - 0.082 13.4 8.5 0.12 12.9 0.3 2.7 2 1 0 2 2 2 0 AAA domain DLIC PF05783.11 KIY64095.1 - 0.18 10.6 0.0 0.3 9.9 0.0 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) MukB PF04310.12 KIY64095.1 - 0.23 11.2 0.6 29 4.4 0.1 2.6 2 0 0 2 2 2 0 MukB N-terminal NTPase_1 PF03266.15 KIY64095.1 - 0.28 11.1 2.9 9.6 6.1 0.1 3.0 4 0 0 4 4 3 0 NTPase Isy1 PF06246.12 KIY64096.1 - 3.4e-89 298.8 1.4 3.8e-89 298.6 1.4 1.0 1 0 0 1 1 1 1 Isy1-like splicing family PFK PF00365.20 KIY64097.1 - 5e-184 610.1 0.3 2.2e-100 335.7 0.1 2.9 2 1 0 2 2 2 2 Phosphofructokinase CheY-binding PF09078.11 KIY64097.1 - 0.19 11.8 0.0 0.46 10.7 0.0 1.5 1 0 0 1 1 1 0 CheY binding CRAL_TRIO PF00650.20 KIY64098.1 - 1.1e-36 125.9 0.0 2.1e-36 125.0 0.0 1.4 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KIY64098.1 - 1e-10 41.6 0.3 2.7e-10 40.3 0.3 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain UQ_con PF00179.26 KIY64099.1 - 1.1e-15 57.6 0.0 1.1e-15 57.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KIY64099.1 - 0.0056 16.9 0.0 0.0057 16.9 0.0 1.2 1 0 0 1 1 1 1 RWD domain VHS PF00790.19 KIY64100.1 - 2.3e-33 115.0 0.1 4.3e-33 114.1 0.1 1.4 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.28 KIY64100.1 - 7.1e-14 51.1 0.1 1.2e-13 50.4 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KIY64100.1 - 3.1e-13 49.3 0.1 6e-13 48.4 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KIY64100.1 - 4.6e-13 48.6 0.1 8.8e-13 47.7 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.14 KIY64100.1 - 2.5e-11 43.7 0.9 5.6e-11 42.6 0.9 1.6 1 0 0 1 1 1 1 GAT domain UIM PF02809.20 KIY64100.1 - 0.0016 18.2 0.5 0.0016 18.2 0.5 2.2 2 0 0 2 2 2 1 Ubiquitin interaction motif IKBKB_SDD PF18397.1 KIY64100.1 - 0.12 11.7 1.6 0.23 10.7 0.4 1.8 2 0 0 2 2 2 0 IQBAL scaffold dimerization domain IlvN PF07991.12 KIY64101.1 - 1.5e-46 158.0 0.1 2.3e-46 157.4 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 KIY64101.1 - 5.3e-39 133.8 0.0 7.9e-39 133.2 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.15 KIY64101.1 - 0.085 13.0 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase CotJA PF11007.8 KIY64101.1 - 0.14 12.0 0.0 0.51 10.2 0.0 2.0 1 0 0 1 1 1 0 Spore coat associated protein JA (CotJA) Mago_nashi PF02792.14 KIY64102.1 - 1.5e-75 252.1 0.2 1.7e-75 251.9 0.2 1.0 1 0 0 1 1 1 1 Mago nashi protein PQ-loop PF04193.14 KIY64103.1 - 1.1e-23 82.8 2.0 5.6e-11 42.1 0.2 2.5 2 0 0 2 2 2 2 PQ loop repeat Hydrolase_4 PF12146.8 KIY64104.1 - 8e-23 80.9 0.1 1.6e-18 66.8 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KIY64104.1 - 4e-13 50.5 0.0 5.4e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KIY64104.1 - 1.6e-11 44.4 0.2 7.8e-09 35.5 0.2 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 KIY64104.1 - 4e-07 30.1 0.1 0.00089 19.1 0.0 3.0 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 KIY64104.1 - 0.00016 21.2 0.0 0.00038 20.0 0.0 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 KIY64104.1 - 0.00019 21.1 0.0 0.087 12.4 0.0 2.1 1 1 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.18 KIY64104.1 - 0.00028 20.5 0.0 0.0014 18.2 0.0 1.9 1 1 0 1 1 1 1 Dienelactone hydrolase family Thioesterase PF00975.20 KIY64104.1 - 0.00053 20.2 0.0 0.00084 19.5 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.13 KIY64104.1 - 0.00083 19.1 0.0 0.0011 18.7 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein DUF1057 PF06342.12 KIY64104.1 - 0.0037 16.3 0.0 0.0054 15.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_5 PF12695.7 KIY64104.1 - 0.017 14.9 0.0 0.13 12.0 0.0 2.4 2 1 0 2 2 2 0 Alpha/beta hydrolase family Esterase PF00756.20 KIY64104.1 - 0.019 14.6 0.0 0.029 14.0 0.0 1.2 1 0 0 1 1 1 0 Putative esterase BAAT_C PF08840.11 KIY64104.1 - 0.029 14.3 0.0 8.4 6.3 0.0 2.2 1 1 1 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.13 KIY64104.1 - 0.065 13.1 0.2 0.16 11.8 0.2 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold FSH1 PF03959.13 KIY64104.1 - 0.13 11.9 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) PAF-AH_p_II PF03403.13 KIY64104.1 - 0.14 10.6 0.1 6.2 5.2 0.0 2.1 1 1 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II CDPS PF16715.5 KIY64107.1 - 0.018 14.7 2.6 0.023 14.3 2.6 1.1 1 0 0 1 1 1 0 Cyclodipeptide synthase RRN3 PF05327.11 KIY64107.1 - 0.1 11.1 14.8 0.13 10.8 14.8 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF2663 PF10864.8 KIY64107.1 - 0.1 13.0 2.9 0.2 12.1 2.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2663) TFB6 PF17110.5 KIY64107.1 - 0.45 10.2 13.5 1.1 9.0 13.5 1.7 1 1 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH SAPS PF04499.15 KIY64107.1 - 0.61 8.8 9.8 0.7 8.6 9.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein V_ATPase_I PF01496.19 KIY64107.1 - 1.8 6.4 3.8 2.3 6.0 3.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Nop14 PF04147.12 KIY64107.1 - 2.2 6.4 26.4 2.4 6.3 26.4 1.2 1 0 0 1 1 1 0 Nop14-like family DUF4746 PF15928.5 KIY64107.1 - 4.1 6.7 11.0 5.4 6.4 11.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF913 PF06025.12 KIY64107.1 - 8.1 5.3 7.1 9.7 5.0 7.1 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) COA2 PF17051.5 KIY64109.1 - 0.041 13.9 0.3 0.062 13.4 0.3 1.4 1 1 0 1 1 1 0 Cytochrome C oxidase assembly factor 2 ADK PF00406.22 KIY64110.1 - 2.4e-58 196.5 0.0 2.9e-58 196.2 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KIY64110.1 - 1.4e-22 80.5 0.1 3e-22 79.5 0.0 1.5 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 KIY64110.1 - 1.4e-16 60.1 0.0 3.5e-16 58.9 0.0 1.7 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_18 PF13238.6 KIY64110.1 - 0.00016 22.2 0.0 0.00039 21.0 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KIY64110.1 - 0.00066 19.8 0.0 0.0011 19.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain DDOST_48kD PF03345.14 KIY64111.1 - 1.8e-115 386.1 0.0 2.3e-115 385.8 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta Self-incomp_S1 PF05938.11 KIY64113.1 - 0.0015 19.1 0.0 0.68 10.5 0.0 3.1 1 1 2 3 3 3 1 Plant self-incompatibility protein S1 M16C_assoc PF08367.11 KIY64113.1 - 0.028 13.6 0.6 1.2 8.2 0.1 2.8 4 0 0 4 4 4 0 Peptidase M16C associated DUF5304 PF17230.2 KIY64113.1 - 0.065 13.5 1.1 1.9 8.7 0.1 2.5 1 1 1 2 2 2 0 Family of unknown function (DUF5304) Trns_repr_metal PF02583.17 KIY64113.1 - 4.5 7.7 8.3 1.5 9.3 0.3 3.6 2 1 2 4 4 4 0 Metal-sensitive transcriptional repressor DUF1691 PF07950.11 KIY64115.1 - 0.0087 16.8 0.1 0.066 13.9 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1691) DUF4538 PF15061.6 KIY64115.1 - 0.28 11.0 0.5 2.9 7.7 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4538) Swi5 PF07061.11 KIY64116.1 - 1.4e-20 73.2 1.9 1.6e-20 72.9 1.9 1.0 1 0 0 1 1 1 1 Swi5 Macoilin PF09726.9 KIY64116.1 - 0.0018 16.9 0.9 0.002 16.8 0.9 1.0 1 0 0 1 1 1 1 Macoilin family Tn7_Tnp_TnsA_C PF08721.11 KIY64116.1 - 0.0092 16.6 0.2 0.067 13.8 0.1 1.9 2 0 0 2 2 2 1 TnsA endonuclease C terminal Glyco_hydro_67N PF03648.14 KIY64116.1 - 0.022 15.0 0.3 0.026 14.8 0.3 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 67 N-terminus DUF1415 PF07209.12 KIY64116.1 - 0.046 13.5 0.8 0.057 13.2 0.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1415) Occludin_ELL PF07303.13 KIY64116.1 - 0.06 14.1 0.7 0.09 13.5 0.7 1.4 1 1 0 1 1 1 0 Occludin homology domain Shugoshin_N PF07558.11 KIY64116.1 - 0.1 12.5 0.1 0.2 11.6 0.1 1.5 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region Med21 PF11221.8 KIY64116.1 - 0.11 12.7 3.1 0.085 13.1 1.5 1.6 1 1 0 1 1 1 0 Subunit 21 of Mediator complex ABC_tran_CTD PF16326.5 KIY64116.1 - 0.25 11.6 4.1 0.97 9.7 4.1 2.0 1 1 0 1 1 1 0 ABC transporter C-terminal domain FUSC PF04632.12 KIY64116.1 - 0.26 9.8 2.0 0.28 9.7 2.0 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF3007 PF11460.8 KIY64116.1 - 0.29 11.4 1.7 12 6.2 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3007) DivIC PF04977.15 KIY64116.1 - 0.37 10.6 3.3 0.29 11.0 1.7 1.6 1 1 1 2 2 2 0 Septum formation initiator bZIP_2 PF07716.15 KIY64116.1 - 0.81 9.8 3.7 0.98 9.5 0.8 2.0 2 0 0 2 2 2 0 Basic region leucine zipper Nop14 PF04147.12 KIY64117.1 - 0.13 10.5 47.4 0.18 10.0 47.4 1.2 1 0 0 1 1 1 0 Nop14-like family Endonuc_Holl PF10107.9 KIY64117.1 - 1.7 8.5 4.3 3.7 7.4 4.3 1.5 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase BUD22 PF09073.10 KIY64117.1 - 3.9 6.7 42.2 8.6 5.6 42.2 1.5 1 0 0 1 1 1 0 BUD22 Phosphodiest PF01663.22 KIY64118.1 - 3e-12 46.8 0.2 5.6e-12 45.9 0.2 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 KIY64118.1 - 0.00042 19.8 0.4 0.0007 19.0 0.4 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 KIY64118.1 - 0.0067 15.9 0.0 0.0095 15.4 0.0 1.4 1 0 0 1 1 1 1 Sulfatase Nop14 PF04147.12 KIY64121.1 - 0.025 12.8 33.6 0.026 12.7 33.6 1.1 1 0 0 1 1 1 0 Nop14-like family Mpp10 PF04006.12 KIY64121.1 - 0.053 12.0 25.6 0.049 12.1 25.6 1.1 1 0 0 1 1 1 0 Mpp10 protein SDA1 PF05285.12 KIY64121.1 - 0.066 12.6 31.9 0.065 12.7 31.9 1.2 1 0 0 1 1 1 0 SDA1 SpoIIIAH PF12685.7 KIY64121.1 - 0.21 11.4 12.1 0.27 11.0 12.1 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein Paf1 PF03985.13 KIY64121.1 - 0.29 10.1 21.7 0.37 9.8 21.7 1.1 1 0 0 1 1 1 0 Paf1 CDC45 PF02724.14 KIY64121.1 - 0.33 9.2 24.9 0.36 9.1 24.9 1.3 1 0 0 1 1 1 0 CDC45-like protein V_ATPase_I PF01496.19 KIY64121.1 - 0.36 8.7 6.5 0.45 8.4 6.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Zip PF02535.22 KIY64121.1 - 0.98 8.6 6.1 0.93 8.6 6.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DNA_pol_phi PF04931.13 KIY64121.1 - 1.1 7.3 43.9 1.7 6.6 43.9 1.4 1 0 0 1 1 1 0 DNA polymerase phi NPR3 PF03666.13 KIY64121.1 - 1.4 7.6 9.9 1.6 7.5 9.9 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF913 PF06025.12 KIY64121.1 - 1.9 7.4 9.0 2 7.3 9.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) BUD22 PF09073.10 KIY64121.1 - 2 7.7 29.3 2 7.7 29.3 1.2 1 0 0 1 1 1 0 BUD22 CNDH2_C PF16858.5 KIY64121.1 - 4.4 7.1 19.9 4.9 6.9 19.9 1.1 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term DUF2428 PF10350.9 KIY64121.1 - 4.6 6.4 6.6 6.2 6.0 6.6 1.3 1 0 0 1 1 1 0 Putative death-receptor fusion protein (DUF2428) RR_TM4-6 PF06459.12 KIY64121.1 - 5 6.9 13.4 6.1 6.6 13.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CobT PF06213.12 KIY64121.1 - 6.7 6.0 33.5 8.4 5.7 33.5 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT MCM_bind PF09739.9 KIY64121.1 - 8.9 4.6 7.9 10 4.4 7.9 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor tRNA-synt_1g PF09334.11 KIY64123.1 - 2.9e-89 299.6 0.7 3.8e-88 295.9 0.7 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KIY64123.1 - 2.6e-18 65.6 1.6 2.1e-08 32.9 0.1 3.5 1 1 2 4 4 4 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 KIY64123.1 - 2e-07 30.7 0.0 0.0014 18.1 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Glyco_hydro_76 PF03663.14 KIY64124.1 - 2.4e-31 109.6 21.8 3e-31 109.3 21.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 DUF3775 PF12616.8 KIY64124.1 - 0.098 12.7 0.1 0.22 11.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3775) Acetyltransf_7 PF13508.7 KIY64125.1 - 0.00015 22.1 0.0 0.0003 21.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KIY64125.1 - 0.0024 17.8 0.0 0.005 16.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIY64125.1 - 0.0064 16.4 0.0 0.019 14.9 0.0 1.8 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_1 PF00583.25 KIY64125.1 - 0.0092 16.2 0.0 0.013 15.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 KIY64125.1 - 0.092 12.8 0.0 6.7 6.8 0.0 2.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain ABC2_membrane PF01061.24 KIY64126.1 - 1.9e-35 122.2 17.6 1.9e-35 122.2 17.6 2.4 3 0 0 3 3 3 1 ABC-2 type transporter ABC_tran PF00005.27 KIY64126.1 - 5.6e-22 78.7 0.0 1.6e-21 77.2 0.0 1.8 2 0 0 2 2 2 1 ABC transporter AAA_29 PF13555.6 KIY64126.1 - 0.0033 17.1 0.1 0.0086 15.8 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KIY64126.1 - 0.0047 16.8 0.1 0.015 15.2 0.1 1.8 2 0 0 2 2 2 1 RsgA GTPase AAA_21 PF13304.6 KIY64126.1 - 0.0052 16.6 0.8 0.33 10.7 0.1 2.3 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system IstB_IS21 PF01695.17 KIY64126.1 - 0.023 14.4 0.0 2.7 7.7 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_22 PF13401.6 KIY64126.1 - 0.029 14.6 0.0 0.078 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KIY64126.1 - 0.059 13.7 0.0 0.1 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain SMC_N PF02463.19 KIY64126.1 - 0.068 12.6 0.1 6.3 6.2 0.0 2.5 2 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_18 PF13238.6 KIY64126.1 - 0.07 13.7 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KIY64126.1 - 0.082 13.2 0.2 0.14 12.4 0.2 1.3 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 KIY64126.1 - 0.094 12.6 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain NACHT PF05729.12 KIY64126.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain TsaE PF02367.17 KIY64126.1 - 0.12 12.4 0.3 0.39 10.7 0.2 1.8 1 1 1 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_23 PF13476.6 KIY64126.1 - 0.13 12.8 0.0 0.21 12.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KIY64126.1 - 0.15 12.2 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF1270 PF06900.11 KIY64126.1 - 7.9 6.9 8.2 9.7 6.7 0.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1270) zf-MYND PF01753.18 KIY64127.1 - 2.4e-07 30.7 13.2 5.7e-07 29.5 13.2 1.6 1 0 0 1 1 1 1 MYND finger TMEM239 PF15841.5 KIY64127.1 - 0.047 13.6 0.2 0.11 12.4 0.0 1.7 2 0 0 2 2 2 0 Transmembrane protein 239 family zf-HIT PF04438.16 KIY64127.1 - 7.9 6.5 9.4 21 5.1 9.4 1.7 1 0 0 1 1 1 0 HIT zinc finger zf-MYND PF01753.18 KIY64128.1 - 2.7e-05 24.2 10.1 8.6e-05 22.5 10.1 1.9 1 0 0 1 1 1 1 MYND finger DUF4578 PF15147.6 KIY64128.1 - 0.087 13.7 0.0 0.21 12.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4578) E1-E2_ATPase PF00122.20 KIY64129.1 - 1e-51 175.1 3.2 1e-51 175.1 3.2 2.7 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KIY64129.1 - 5.1e-45 153.4 7.7 5.1e-45 153.4 7.7 1.7 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KIY64129.1 - 2.9e-22 80.0 0.3 1.5e-21 77.7 0.3 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KIY64129.1 - 1.4e-19 70.0 0.1 2.7e-19 69.0 0.1 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KIY64129.1 - 3e-18 65.3 0.3 7.7e-18 64.0 0.0 1.9 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KIY64129.1 - 5e-08 33.0 1.4 3.6e-06 26.9 1.1 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KIY64129.1 - 2.3e-05 24.9 0.0 7.7e-05 23.2 0.0 2.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase zf-C3HC4_3 PF13920.6 KIY64130.1 - 0.027 14.3 9.9 0.052 13.4 9.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FliO PF04347.13 KIY64130.1 - 0.042 14.2 0.0 0.17 12.2 0.0 2.1 1 1 0 1 1 1 0 Flagellar biosynthesis protein, FliO zf-RING_2 PF13639.6 KIY64130.1 - 0.044 14.1 12.0 0.071 13.4 12.0 1.4 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.25 KIY64130.1 - 0.55 10.1 13.1 0.95 9.4 13.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIY64130.1 - 1.1 9.2 11.7 1.9 8.5 11.7 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_4 PF14570.6 KIY64130.1 - 3.6 7.5 9.0 8.1 6.3 9.1 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Peptidase_M22 PF00814.25 KIY64131.1 - 0.076 12.7 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Glycoprotease family Rox3 PF08633.10 KIY64131.1 - 0.092 13.0 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 Rox3 mediator complex subunit Macoilin PF09726.9 KIY64132.1 - 0.00016 20.4 3.8 0.00022 20.0 3.8 1.1 1 0 0 1 1 1 1 Macoilin family Filament PF00038.21 KIY64132.1 - 0.011 15.4 3.0 0.019 14.6 3.0 1.4 1 0 0 1 1 1 0 Intermediate filament protein KELK PF15796.5 KIY64132.1 - 0.015 15.7 3.1 0.037 14.5 3.1 1.6 1 0 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Lzipper-MIP1 PF14389.6 KIY64132.1 - 0.017 15.4 5.5 0.18 12.1 0.3 2.6 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 SF-assemblin PF06705.11 KIY64132.1 - 0.051 12.9 1.2 0.098 12.0 1.2 1.4 1 0 0 1 1 1 0 SF-assemblin/beta giardin MscS_porin PF12795.7 KIY64132.1 - 0.052 13.1 7.3 0.1 12.1 7.3 1.5 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain UBA_e1_thiolCys PF10585.9 KIY64132.1 - 0.078 12.9 0.2 0.15 12.0 0.2 1.4 1 0 0 1 1 1 0 Ubiquitin-activating enzyme active site ADIP PF11559.8 KIY64132.1 - 0.083 13.0 6.0 0.21 11.7 6.0 1.6 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding JmjC PF02373.22 KIY64133.1 - 1.3e-10 41.7 0.2 4.4e-10 40.0 0.0 2.0 2 0 0 2 2 2 1 JmjC domain, hydroxylase Matrilin_ccoil PF10393.9 KIY64133.1 - 0.077 12.9 0.0 0.27 11.1 0.0 1.9 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin UPF0547 PF10571.9 KIY64133.1 - 0.08 13.0 0.3 0.08 13.0 0.3 2.6 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Cupin_4 PF08007.12 KIY64133.1 - 0.1 12.1 0.1 0.18 11.3 0.1 1.3 1 0 0 1 1 1 0 Cupin superfamily protein SHQ1 PF04925.15 KIY64134.1 - 1.5e-51 174.4 0.0 2.4e-51 173.8 0.0 1.2 1 0 0 1 1 1 1 SHQ1 protein PIH1_CS PF18201.1 KIY64134.1 - 0.00035 20.9 0.0 0.00074 19.9 0.0 1.5 1 0 0 1 1 1 1 PIH1 CS-like domain CS PF04969.16 KIY64134.1 - 0.071 14.1 0.0 0.13 13.3 0.0 1.5 1 0 0 1 1 1 0 CS domain Acetyltransf_15 PF17013.5 KIY64134.1 - 0.13 11.7 0.0 4.7 6.6 0.0 2.2 2 0 0 2 2 2 0 Putative acetyl-transferase Hamartin PF04388.12 KIY64135.1 - 1.6 7.3 9.5 1.8 7.1 9.5 1.1 1 0 0 1 1 1 0 Hamartin protein Glyco_tranf_2_3 PF13641.6 KIY64136.1 - 2.2e-31 109.5 0.0 3.1e-31 109.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KIY64136.1 - 3.3e-09 36.8 0.0 4.6e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KIY64136.1 - 2.5e-06 27.1 0.0 2e-05 24.2 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 21 CBP4 PF07960.11 KIY64137.1 - 1.7e-11 44.1 0.0 2.2e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 CBP4 zf-C2H2 PF00096.26 KIY64138.1 - 2.6e-11 43.3 29.4 0.0011 19.3 0.3 6.6 7 0 0 7 7 6 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIY64138.1 - 1e-10 41.5 28.7 0.015 16.1 0.2 6.6 7 0 0 7 7 6 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KIY64138.1 - 2.1e-06 27.9 25.0 0.03 14.6 2.0 6.0 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KIY64138.1 - 0.00068 19.9 17.5 0.32 11.3 0.1 4.2 1 1 3 4 4 4 1 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 KIY64138.1 - 0.0016 18.3 0.2 0.0016 18.3 0.2 5.3 6 1 0 6 6 6 1 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KIY64138.1 - 0.0073 16.6 8.8 0.11 12.8 0.2 2.6 2 1 0 2 2 2 1 C2H2-type zinc ribbon zf-met PF12874.7 KIY64138.1 - 0.013 15.9 20.5 0.45 11.0 0.8 5.3 6 0 0 6 6 6 0 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.10 KIY64138.1 - 0.014 15.5 2.3 0.014 15.5 2.3 4.0 2 2 4 6 6 6 0 Zinc ribbon domain zf-Di19 PF05605.12 KIY64138.1 - 0.015 15.6 2.4 0.015 15.6 2.4 4.4 2 2 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zinc_ribbon_5 PF13719.6 KIY64138.1 - 0.029 14.1 10.7 0.2 11.4 0.1 4.3 4 0 0 4 4 4 0 zinc-ribbon domain zinc_ribbon_9 PF14369.6 KIY64138.1 - 0.058 13.7 14.5 0.71 10.2 0.1 4.6 4 0 0 4 4 4 0 zinc-ribbon zf-C2HC_2 PF13913.6 KIY64138.1 - 0.07 13.0 10.2 0.24 11.3 0.1 4.3 4 0 0 4 4 4 0 zinc-finger of a C2HC-type zinc_ribbon_4 PF13717.6 KIY64138.1 - 0.2 11.6 11.2 3.9 7.5 0.0 4.4 4 0 0 4 4 4 0 zinc-ribbon domain zf-C3HC4_4 PF15227.6 KIY64138.1 - 0.27 11.4 11.4 6.5 7.0 0.8 4.8 4 1 1 5 5 5 0 zinc finger of C3HC4-type, RING zf-TFIIB PF13453.6 KIY64138.1 - 0.34 10.3 5.9 5.5 6.4 0.1 3.6 3 0 0 3 3 3 0 Transcription factor zinc-finger FOXP-CC PF16159.5 KIY64138.1 - 0.43 11.2 12.6 2.9 8.6 0.4 4.4 3 2 2 5 5 5 0 FOXP coiled-coil domain zf-C2H2_9 PF16293.5 KIY64138.1 - 0.56 10.1 11.8 0.99 9.3 0.0 3.9 4 1 1 5 5 4 0 C2H2 type zinc-finger (1 copy) zf-C2H2_11 PF16622.5 KIY64138.1 - 0.72 9.7 14.8 19 5.1 0.6 5.6 5 1 1 6 6 6 0 zinc-finger C2H2-type zf-H2C2_2 PF13465.6 KIY64138.1 - 2.1 8.9 27.2 0.76 10.3 0.2 6.7 7 1 0 7 7 7 0 Zinc-finger double domain TF_Zn_Ribbon PF08271.12 KIY64138.1 - 2.9 7.5 7.3 2.4 7.7 0.2 3.1 3 0 0 3 3 3 0 TFIIB zinc-binding CpXC PF14353.6 KIY64138.1 - 3.5 7.7 10.7 4 7.5 0.2 3.0 2 2 1 3 3 3 0 CpXC protein Ribosomal_S27e PF01667.17 KIY64138.1 - 4.5 7.1 6.3 6.8 6.5 0.1 3.3 4 0 0 4 4 3 0 Ribosomal protein S27 HypA PF01155.19 KIY64138.1 - 5.9 6.9 14.5 1.6 8.8 0.1 3.5 1 1 1 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C3HC4 PF00097.25 KIY64138.1 - 8.2 6.4 19.0 45 4.0 0.3 5.2 4 1 1 5 5 5 0 Zinc finger, C3HC4 type (RING finger) Nuc_sug_transp PF04142.15 KIY64140.1 - 1.3e-08 34.4 0.7 1.8e-08 33.9 0.7 1.3 1 0 0 1 1 1 1 Nucleotide-sugar transporter TPT PF03151.16 KIY64140.1 - 1.4e-07 31.2 4.8 4.8e-05 22.8 0.3 2.1 2 0 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.20 KIY64140.1 - 8.2e-07 29.3 29.6 8.8e-06 25.9 5.7 2.7 2 1 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 KIY64140.1 - 0.0011 18.3 0.5 0.0011 18.3 0.5 1.7 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport UAA PF08449.11 KIY64140.1 - 0.0077 15.5 6.3 0.012 14.8 6.3 1.2 1 0 0 1 1 1 1 UAA transporter family Trp_oprn_chp PF09534.10 KIY64140.1 - 0.11 12.3 1.7 0.16 11.8 0.5 1.8 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) CRT-like PF08627.10 KIY64140.1 - 0.67 8.8 10.2 6.1 5.7 10.2 2.3 1 1 0 1 1 1 0 CRT-like, chloroquine-resistance transporter-like zf-C2H2 PF00096.26 KIY64141.1 - 3.9e-13 49.1 45.8 0.007 16.8 0.1 9.0 9 0 0 9 9 9 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIY64141.1 - 1.6e-11 44.0 50.8 0.059 14.2 0.1 9.2 9 0 0 9 9 9 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KIY64141.1 - 4.1e-06 26.9 46.1 0.0032 17.7 0.0 8.0 9 0 0 9 9 8 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KIY64141.1 - 0.00035 20.5 0.1 0.00035 20.5 0.1 5.7 6 1 0 6 6 6 2 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KIY64141.1 - 0.0048 17.2 40.3 0.15 12.4 3.3 7.7 3 3 5 8 8 8 2 C2H2 type zinc-finger (2 copies) zf-C2H2_9 PF16293.5 KIY64141.1 - 0.012 15.4 10.0 0.28 11.1 0.0 5.0 3 2 2 5 5 5 0 C2H2 type zinc-finger (1 copy) zf-C2H2_8 PF15909.5 KIY64141.1 - 0.023 15.0 0.1 0.023 15.0 0.1 4.1 3 1 1 4 4 4 0 C2H2-type zinc ribbon zf-met PF12874.7 KIY64141.1 - 0.042 14.3 0.0 0.042 14.3 0.0 8.2 9 0 0 9 9 8 0 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 KIY64141.1 - 0.076 13.5 33.4 2.1 8.9 0.4 7.2 7 0 0 7 7 7 0 Zinc-finger double domain Tox-REase-5 PF15648.6 KIY64141.1 - 0.12 12.9 0.1 0.24 11.9 0.1 1.4 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 5 zinc_ribbon_4 PF13717.6 KIY64141.1 - 0.96 9.4 20.8 1.5 8.8 0.0 6.4 6 0 0 6 6 6 0 zinc-ribbon domain zf-C2HC_2 PF13913.6 KIY64141.1 - 1.2 9.2 0.0 1.2 9.2 0.0 5.9 6 0 0 6 6 6 0 zinc-finger of a C2HC-type zf-C2H2_11 PF16622.5 KIY64141.1 - 3.4 7.5 0.0 3.4 7.5 0.0 7.6 8 0 0 8 8 8 0 zinc-finger C2H2-type Rad50_zn_hook PF04423.14 KIY64141.1 - 8 6.4 8.0 4 7.4 0.0 3.8 4 0 0 4 4 4 0 Rad50 zinc hook motif Chorismate_bind PF00425.18 KIY64142.1 - 8.7e-92 307.3 0.0 1.2e-91 306.9 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 KIY64142.1 - 1.6e-25 90.0 0.0 1.1e-24 87.3 0.0 2.3 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region DUF3446 PF11928.8 KIY64143.1 - 0.017 15.4 0.2 0.031 14.6 0.1 1.5 1 1 0 1 1 1 0 Early growth response N-terminal domain DDE_1 PF03184.19 KIY64144.1 - 3.5e-06 26.8 0.0 7e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease SLAC1 PF03595.17 KIY64145.1 - 8.5e-70 235.6 44.8 9.6e-70 235.4 44.8 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Sugar_tr PF00083.24 KIY64148.1 - 4.5e-104 348.8 23.4 5.3e-104 348.6 23.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY64148.1 - 1.7e-14 53.5 36.5 3.4e-12 46.0 9.1 2.4 1 1 0 2 2 2 2 Major Facilitator Superfamily EPSP_synthase PF00275.20 KIY64149.1 - 4.6e-122 407.7 0.0 7.5e-122 407.0 0.0 1.3 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 KIY64149.1 - 1.6e-98 329.1 0.0 2.4e-97 325.2 0.0 2.3 2 0 0 2 2 2 1 3-dehydroquinate synthase DHquinase_I PF01487.15 KIY64149.1 - 3.5e-54 184.5 0.0 5.6e-54 183.8 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 KIY64149.1 - 1.2e-30 106.7 0.0 2.6e-29 102.4 0.0 2.3 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.11 KIY64149.1 - 4.1e-25 87.8 0.0 1e-24 86.6 0.0 1.8 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Fe-ADH_2 PF13685.6 KIY64149.1 - 1.5e-09 38.0 0.0 3.2e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Shikimate_DH PF01488.20 KIY64149.1 - 2.1e-08 34.3 0.0 6.3e-08 32.8 0.0 1.8 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase SDH_C PF18317.1 KIY64149.1 - 8.2e-07 28.7 0.2 2e-06 27.4 0.2 1.7 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Fe-ADH PF00465.19 KIY64149.1 - 0.009 14.9 1.0 0.035 12.9 0.1 2.3 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase AAA_33 PF13671.6 KIY64149.1 - 0.17 12.0 0.0 0.5 10.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain 6PF2K PF01591.18 KIY64149.1 - 0.17 11.2 0.0 0.3 10.4 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AA_permease PF00324.21 KIY64150.1 - 1.1e-98 331.0 44.9 1.3e-98 330.7 44.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KIY64150.1 - 1.6e-27 96.4 49.7 2e-27 96.1 49.7 1.0 1 0 0 1 1 1 1 Amino acid permease Per1 PF04080.13 KIY64151.1 - 1.7e-92 309.8 10.6 2.2e-92 309.5 10.6 1.1 1 0 0 1 1 1 1 Per1-like family RRM_1 PF00076.22 KIY64154.1 - 3.5e-14 52.4 0.2 1.4e-05 24.8 0.0 2.9 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KIY64154.1 - 4.3e-07 29.9 0.0 8.4e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif CI-B14_5a PF07347.12 KIY64155.1 - 0.018 14.9 0.7 0.03 14.2 0.2 1.7 1 1 0 1 1 1 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) Smg4_UPF3 PF03467.15 KIY64156.1 - 1e-46 159.2 2.2 1.4e-46 158.7 0.0 2.1 2 0 0 2 2 2 1 Smg-4/UPF3 family G_glu_transpept PF01019.21 KIY64157.1 - 2.1e-143 478.8 0.0 2.7e-143 478.5 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Asparaginase_2 PF01112.18 KIY64157.1 - 0.069 12.2 0.1 0.19 10.7 0.1 1.7 1 0 0 1 1 1 0 Asparaginase HhH-GPD PF00730.25 KIY64158.1 - 3.2e-14 53.3 0.0 5.5e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Abhydrolase_1 PF00561.20 KIY64159.1 - 5.2e-17 62.3 0.0 1e-16 61.4 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIY64159.1 - 1.1e-09 39.2 0.0 1.5e-09 38.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIY64159.1 - 4.5e-09 35.9 0.1 1.3e-08 34.5 0.1 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Amidohydro_3 PF07969.11 KIY64160.1 - 5.8e-78 263.4 0.0 7.2e-78 263.1 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 KIY64160.1 - 7e-11 42.0 0.0 1.3e-09 37.9 0.0 2.2 2 0 0 2 2 2 1 Amidohydrolase family MerE PF05052.12 KIY64161.1 - 0.17 11.8 0.2 0.17 11.8 0.2 2.2 2 1 0 2 2 2 0 MerE protein RRM_1 PF00076.22 KIY64162.1 - 4.2e-08 32.9 0.2 0.00019 21.2 0.0 4.2 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Inositol_P PF00459.25 KIY64163.1 - 1.5e-56 191.9 0.0 1.7e-56 191.7 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family BAR_3 PF16746.5 KIY64164.1 - 0.0038 17.0 1.9 0.0038 17.0 1.9 1.7 2 0 0 2 2 2 1 BAR domain of APPL family Rubrerythrin PF02915.17 KIY64164.1 - 0.0078 16.6 1.1 0.0078 16.6 1.1 2.4 2 1 0 2 2 2 1 Rubrerythrin Dynamitin PF04912.14 KIY64164.1 - 0.015 14.7 1.2 0.015 14.7 1.2 2.2 2 0 0 2 2 2 0 Dynamitin SAM_1 PF00536.30 KIY64165.1 - 0.0071 16.8 0.0 0.031 14.7 0.0 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KIY64165.1 - 0.04 14.0 0.0 0.19 11.9 0.0 2.0 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) DUF1192 PF06698.11 KIY64165.1 - 1.7 8.8 4.9 12 6.0 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) HMG_box PF00505.19 KIY64166.1 - 1.4e-09 38.2 2.8 6.7e-09 36.0 2.8 2.1 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KIY64166.1 - 0.0012 19.3 0.6 0.0012 19.3 0.6 1.9 2 1 0 2 2 2 1 HMG-box domain CMD PF02627.20 KIY64167.1 - 0.00088 19.3 0.6 0.016 15.2 0.0 2.5 2 1 0 2 2 2 1 Carboxymuconolactone decarboxylase family Mod_r PF07200.13 KIY64168.1 - 3.2e-42 144.1 3.1 4e-42 143.8 3.1 1.0 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein RPAP1_N PF08621.10 KIY64168.1 - 0.083 12.7 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 RPAP1-like, N-terminal Hypoth_Ymh PF09509.10 KIY64168.1 - 0.097 12.6 0.6 4.7 7.1 0.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (Hypoth_ymh) KH_6 PF15985.5 KIY64169.1 - 5.1e-15 55.5 0.0 1.1e-14 54.5 0.0 1.6 1 0 0 1 1 1 1 KH domain Rrp40_N PF18311.1 KIY64169.1 - 1.1e-11 44.5 1.4 1.6e-11 43.9 0.5 1.8 2 0 0 2 2 2 1 Exosome complex exonuclease Rrp40 N-terminal domain p450 PF00067.22 KIY64170.1 - 1.9e-63 214.9 0.0 2.2e-63 214.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 tRNA-synt_1g PF09334.11 KIY64171.1 - 1.6e-135 451.8 0.3 2e-135 451.5 0.3 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) WHEP-TRS PF00458.20 KIY64171.1 - 1.4e-08 34.8 4.5 2.9e-08 33.8 4.5 1.6 1 0 0 1 1 1 1 WHEP-TRS domain Anticodon_1 PF08264.13 KIY64171.1 - 4e-07 30.1 0.0 1e-06 28.8 0.0 1.8 1 1 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1 PF00133.22 KIY64171.1 - 0.00024 19.5 0.0 0.0016 16.8 0.0 2.3 2 1 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Nitroreductase PF00881.24 KIY64172.1 - 1.9e-26 93.1 0.0 2.7e-26 92.6 0.0 1.2 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 KIY64172.1 - 4e-06 26.6 0.0 0.069 12.7 0.0 2.3 2 0 0 2 2 2 2 Putative TM nitroreductase UPRTase PF14681.6 KIY64173.1 - 6.6e-76 254.4 0.0 8.2e-76 254.0 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 KIY64173.1 - 0.00039 20.0 0.0 0.0005 19.6 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Abhydrolase_1 PF00561.20 KIY64174.1 - 6.9e-22 78.3 0.2 2.3e-21 76.6 0.2 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIY64174.1 - 2.3e-15 57.8 1.1 3.7e-15 57.1 1.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIY64174.1 - 3.7e-07 29.7 0.0 7.1e-06 25.5 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 APH PF01636.23 KIY64176.1 - 4.3e-12 46.5 0.0 9e-12 45.4 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KIY64176.1 - 0.00015 21.4 0.0 0.00024 20.8 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 KIY64176.1 - 0.045 13.4 0.0 0.32 10.6 0.0 2.2 3 0 0 3 3 3 0 RIO1 family Pkinase PF00069.25 KIY64176.1 - 0.092 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain APH PF01636.23 KIY64177.1 - 3.3e-14 53.4 0.2 5.9e-14 52.6 0.2 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KIY64177.1 - 4.9e-05 23.0 0.0 7.7e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 KIY64177.1 - 0.025 14.2 0.0 0.24 11.0 0.0 2.1 2 0 0 2 2 2 0 RIO1 family Pkinase PF00069.25 KIY64177.1 - 0.056 12.8 0.0 0.14 11.5 0.0 1.6 2 0 0 2 2 2 0 Protein kinase domain SLAC1 PF03595.17 KIY64179.1 - 8.3e-53 179.7 41.3 9.8e-53 179.5 41.3 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF1494 PF07379.11 KIY64179.1 - 0.1 12.4 0.5 0.21 11.4 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1494) CDC45 PF02724.14 KIY64180.1 - 0.012 13.9 3.2 0.015 13.6 3.2 1.3 1 0 0 1 1 1 0 CDC45-like protein Afi1 PF07792.12 KIY64180.1 - 0.25 11.8 4.2 0.37 11.3 0.9 2.2 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Coilin_N PF15862.5 KIY64180.1 - 0.61 9.9 11.0 0.084 12.7 3.8 2.4 2 0 0 2 2 2 0 Coilin N-terminus BUD22 PF09073.10 KIY64180.1 - 0.78 9.0 18.8 0.021 14.2 7.6 2.7 3 0 0 3 3 3 0 BUD22 Secretin_N_2 PF07655.13 KIY64180.1 - 2.7 8.6 12.4 3.1 8.4 9.1 2.3 2 0 0 2 2 2 0 Secretin N-terminal domain DUF4614 PF15391.6 KIY64180.1 - 2.7 8.0 15.8 1.5 8.8 12.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) Macoilin PF09726.9 KIY64180.1 - 4.4 5.7 10.4 6.6 5.2 10.4 1.2 1 0 0 1 1 1 0 Macoilin family DNA_pol_phi PF04931.13 KIY64180.1 - 4.9 5.1 8.1 7.2 4.6 8.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi FAM176 PF14851.6 KIY64180.1 - 8.2 6.1 7.9 1.1 8.9 3.0 1.9 2 0 0 2 2 2 0 FAM176 family SpoIIIAH PF12685.7 KIY64180.1 - 8.8 6.1 10.3 1.6 8.5 4.9 2.2 3 0 0 3 3 3 0 SpoIIIAH-like protein MFS_1 PF07690.16 KIY64181.1 - 1.1e-14 54.1 32.6 1.4e-12 47.2 24.0 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.25 KIY64182.1 - 6.3e-70 235.5 0.0 8.1e-70 235.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY64182.1 - 7.1e-36 123.8 0.0 9.7e-36 123.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 KIY64182.1 - 1.1e-16 61.3 0.6 8.8e-10 39.1 0.0 3.4 2 1 0 2 2 2 2 Adenylate sensor of SNF1-like protein kinase UBA_2 PF08587.11 KIY64182.1 - 7.8e-07 29.1 0.0 1.9e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.6 KIY64182.1 - 1.1e-05 25.0 0.0 1.6e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KIY64182.1 - 0.0015 17.9 0.2 0.0063 15.9 0.2 1.8 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIY64182.1 - 0.0073 16.2 0.3 0.023 14.6 0.2 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KIY64182.1 - 0.021 13.8 0.0 0.032 13.2 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 KIY64182.1 - 0.033 13.8 0.1 0.071 12.7 0.1 1.5 1 0 0 1 1 1 0 RIO1 family NAD_binding_7 PF13241.6 KIY64183.1 - 3.3e-07 30.7 0.0 4e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 Putative NAD(P)-binding DAO PF01266.24 KIY64183.1 - 4.8e-07 29.7 0.1 5.4e-07 29.5 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIY64183.1 - 2.2e-06 27.2 0.0 2.2e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIY64183.1 - 7.4e-06 26.1 0.0 1e-05 25.7 0.0 1.3 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KIY64183.1 - 3.5e-05 24.3 0.1 5.1e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KIY64183.1 - 5.6e-05 22.4 0.0 6.4e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 KIY64183.1 - 0.00018 20.9 0.1 0.00021 20.7 0.1 1.1 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 KIY64183.1 - 0.00032 20.0 0.0 0.00039 19.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 KIY64183.1 - 0.00043 19.5 0.1 0.0005 19.3 0.1 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KIY64183.1 - 0.002 17.4 0.0 0.0022 17.3 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KIY64183.1 - 0.013 14.8 0.2 0.037 13.3 0.1 1.7 1 1 1 2 2 2 0 Thi4 family Shikimate_DH PF01488.20 KIY64183.1 - 0.016 15.3 0.0 0.019 15.0 0.0 1.1 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.14 KIY64183.1 - 0.023 13.4 0.0 0.026 13.3 0.0 1.1 1 0 0 1 1 1 0 HI0933-like protein FAD_oxidored PF12831.7 KIY64183.1 - 0.026 13.9 0.4 0.04 13.3 0.4 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase 3HCDH_N PF02737.18 KIY64183.1 - 0.033 14.1 0.0 0.043 13.7 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 KIY64183.1 - 0.056 13.1 0.2 0.08 12.6 0.2 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA IlvN PF07991.12 KIY64183.1 - 0.1 12.1 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain MFS_1 PF07690.16 KIY64184.1 - 2.9e-12 46.2 29.0 2.9e-12 46.2 29.0 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 KIY64184.1 - 8.3e-08 32.1 9.1 8.3e-08 32.1 9.1 2.8 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 DUF3517 PF12030.8 KIY64184.1 - 0.18 10.7 0.0 0.34 9.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3517) FmdA_AmdA PF03069.15 KIY64185.1 - 2.9e-119 398.2 0.0 3.4e-119 398.0 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family Utp11 PF03998.13 KIY64187.1 - 0.076 12.9 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Utp11 protein Pex16 PF08610.10 KIY64188.1 - 3.6e-102 341.8 1.3 4.1e-102 341.7 1.3 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) NDUFA12 PF05071.16 KIY64190.1 - 2.5e-09 37.9 1.5 3.2e-09 37.5 1.5 1.4 1 1 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Ribosomal_S17_N PF16205.5 KIY64191.1 - 4.4e-32 110.3 0.9 8.1e-32 109.4 0.9 1.5 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 KIY64191.1 - 4.2e-27 94.0 1.3 4.2e-27 94.0 1.3 1.5 2 0 0 2 2 2 1 Ribosomal protein S17 Metallophos PF00149.28 KIY64192.1 - 5.6e-37 128.2 0.0 3.2e-36 125.8 0.0 1.9 1 1 1 2 2 2 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KIY64192.1 - 1.2e-18 67.3 0.0 2e-18 66.5 0.0 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Crust_neurohorm PF01147.17 KIY64192.1 - 1.3 8.9 5.4 4.4 7.2 0.1 2.5 2 0 0 2 2 2 0 Crustacean CHH/MIH/GIH neurohormone family DUF4014 PF13198.6 KIY64193.1 - 0.34 11.3 0.1 0.34 11.3 0.1 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF4014) RRP36 PF06102.12 KIY64194.1 - 1.5e-42 145.4 21.3 2.4e-42 144.7 21.3 1.3 1 0 0 1 1 1 1 rRNA biogenesis protein RRP36 DUF4407 PF14362.6 KIY64194.1 - 4.2 6.6 7.7 7.4 5.8 7.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PHD PF00628.29 KIY64195.1 - 3.6e-13 49.2 22.9 3.3e-08 33.3 8.0 2.4 1 1 1 2 2 2 2 PHD-finger PHD_2 PF13831.6 KIY64195.1 - 5.1e-05 22.8 20.0 0.0024 17.4 1.1 2.7 3 0 0 3 3 3 2 PHD-finger C1_1 PF00130.22 KIY64195.1 - 0.00051 19.9 3.9 0.00051 19.9 3.9 2.6 2 1 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF5564 PF17719.1 KIY64195.1 - 0.022 14.9 2.1 3.6 7.8 0.1 2.6 1 1 0 2 2 2 0 Family of unknown function (DUF5564) Asparaginase_2 PF01112.18 KIY64195.1 - 0.073 12.1 0.1 0.13 11.3 0.1 1.3 1 0 0 1 1 1 0 Asparaginase C1_2 PF03107.16 KIY64195.1 - 0.077 13.3 14.7 0.058 13.7 0.9 2.5 2 0 0 2 2 2 0 C1 domain Prok-RING_1 PF14446.6 KIY64195.1 - 1.5 8.8 15.3 0.33 10.9 2.0 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PHF5 PF03660.14 KIY64195.1 - 8.7 6.6 15.4 0.98 9.7 7.1 2.3 1 1 1 2 2 2 0 PHF5-like protein PKcGMP_CC PF16808.5 KIY64197.1 - 0.0041 16.9 6.5 0.0041 16.9 6.5 2.6 2 0 0 2 2 2 1 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF812 PF05667.11 KIY64197.1 - 0.0055 15.7 3.4 0.0092 14.9 3.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Cast PF10174.9 KIY64197.1 - 0.0095 14.2 8.5 0.015 13.6 8.5 1.1 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone YL1 PF05764.13 KIY64197.1 - 0.02 15.0 0.1 0.02 15.0 0.1 3.0 3 1 0 3 3 1 0 YL1 nuclear protein VPS38 PF17649.1 KIY64197.1 - 0.025 13.5 1.4 0.038 12.9 1.4 1.2 1 0 0 1 1 1 0 Vacuolar protein sorting 38 Tropomyosin PF00261.20 KIY64197.1 - 0.15 11.4 17.3 0.26 10.6 17.3 1.3 1 0 0 1 1 1 0 Tropomyosin Exonuc_VII_L PF02601.15 KIY64197.1 - 0.22 11.1 4.9 0.43 10.1 4.9 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF641 PF04859.12 KIY64197.1 - 0.46 10.8 8.9 1.2 9.5 8.5 1.9 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) DUF16 PF01519.16 KIY64197.1 - 0.83 10.2 5.6 2.2 8.8 5.6 1.7 1 0 0 1 1 1 0 Protein of unknown function DUF16 Fib_alpha PF08702.10 KIY64197.1 - 0.97 9.6 5.5 2.4 8.3 5.5 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family BLOC1_2 PF10046.9 KIY64197.1 - 1.9 8.9 7.3 4.4 7.7 7.3 1.6 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4680 PF15730.5 KIY64197.1 - 2.1 8.7 9.6 0.27 11.6 2.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4680) DUF4200 PF13863.6 KIY64197.1 - 3.1 8.2 17.6 27 5.2 17.6 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) UPF0242 PF06785.11 KIY64197.1 - 3.2 7.8 10.0 7.1 6.7 10.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Spc7 PF08317.11 KIY64197.1 - 4.4 6.1 14.5 8.6 5.1 14.5 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein CorA PF01544.18 KIY64198.1 - 6.9e-20 71.5 0.1 3.9e-13 49.4 0.0 2.6 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein SR-25 PF10500.9 KIY64198.1 - 5.3 6.6 23.6 3.3 7.3 10.6 2.6 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein RRM_1 PF00076.22 KIY64199.1 - 1.6e-41 140.0 0.2 2e-21 75.6 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 KIY64199.1 - 2.2e-12 47.9 0.9 3.9e-10 40.7 0.9 2.5 1 1 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_3 PF08777.11 KIY64199.1 - 0.00014 21.9 0.1 0.034 14.2 0.0 2.8 2 1 0 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.6 KIY64199.1 - 0.00036 20.5 0.0 0.39 10.8 0.1 3.2 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 KIY64199.1 - 0.0037 17.1 0.0 0.41 10.5 0.0 2.4 2 0 0 2 2 2 1 Occluded RNA-recognition motif RRM_5 PF13893.6 KIY64199.1 - 0.02 14.5 0.0 2.1 8.0 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 KIY64199.1 - 0.026 14.6 0.1 3.9 7.6 0.0 2.8 2 0 0 2 2 2 0 Limkain b1 DUF1866 PF08952.11 KIY64199.1 - 0.18 11.6 0.0 0.52 10.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1866) DUF4407 PF14362.6 KIY64199.1 - 8.5 5.6 6.1 14 4.9 6.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) adh_short_C2 PF13561.6 KIY64200.1 - 5.5e-60 202.8 0.1 6.3e-60 202.6 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIY64200.1 - 1.4e-46 158.4 0.1 1.9e-46 158.0 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIY64200.1 - 1.7e-14 54.1 0.1 2.6e-14 53.6 0.1 1.1 1 0 0 1 1 1 1 KR domain Cupin_2 PF07883.11 KIY64201.1 - 1.6e-05 24.5 0.0 3.5e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 KIY64201.1 - 0.028 14.0 0.0 0.043 13.4 0.0 1.2 1 0 0 1 1 1 0 Cupin Cupin_3 PF05899.12 KIY64201.1 - 0.06 13.0 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF861) DAO PF01266.24 KIY64202.1 - 5e-24 85.5 0.0 5.9e-24 85.3 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 KIY64202.1 - 1.1e-06 29.0 0.0 2.6e-06 27.8 0.0 1.8 1 1 0 1 1 1 1 Putative NAD(P)-binding Pyr_redox_2 PF07992.14 KIY64202.1 - 6.8e-06 25.5 0.1 3.4e-05 23.2 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIY64202.1 - 4.1e-05 23.7 0.1 0.00011 22.4 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KIY64202.1 - 0.00015 22.2 0.1 0.00049 20.6 0.1 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KIY64202.1 - 0.0003 20.0 0.0 0.00055 19.1 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 KIY64202.1 - 0.00047 19.5 1.1 0.0037 16.6 0.0 2.3 3 0 0 3 3 3 1 FAD binding domain AlaDh_PNT_C PF01262.21 KIY64202.1 - 0.0011 18.3 0.0 0.0025 17.1 0.0 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 KIY64202.1 - 0.0028 16.8 0.1 0.0052 15.9 0.1 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KIY64202.1 - 0.012 14.9 0.1 0.032 13.5 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KIY64202.1 - 0.035 13.5 1.3 0.32 10.3 0.4 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Shikimate_DH PF01488.20 KIY64202.1 - 0.074 13.1 0.0 0.29 11.2 0.0 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.17 KIY64202.1 - 0.098 11.9 0.1 0.35 10.1 0.0 1.9 2 0 0 2 2 2 0 Thi4 family DUF1666 PF07891.12 KIY64202.1 - 0.16 11.6 0.1 0.25 11.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1666) DAO PF01266.24 KIY64204.1 - 8.1e-15 55.3 0.0 9.1e-15 55.1 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase HORMA PF02301.18 KIY64205.1 - 1.4e-19 70.5 0.1 1.8e-19 70.2 0.1 1.1 1 0 0 1 1 1 1 HORMA domain ATG101 PF07855.12 KIY64205.1 - 0.00084 19.4 0.1 0.0057 16.6 0.1 2.0 1 1 0 1 1 1 1 Autophagy-related protein 101 bacHORMA_2 PF18173.1 KIY64205.1 - 0.12 12.2 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial HORMA domain 2 DAOA PF15199.6 KIY64205.1 - 0.14 12.6 0.0 0.44 11.0 0.0 1.8 1 0 0 1 1 1 0 D-amino acid oxidase activator WD40 PF00400.32 KIY64206.1 - 6.4e-44 147.1 13.6 4.1e-08 33.8 0.1 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 KIY64206.1 - 1.3e-30 106.3 0.0 2.3e-30 105.5 0.0 1.3 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 KIY64206.1 - 2.9e-11 43.5 0.0 0.0012 19.1 0.0 5.1 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KIY64206.1 - 0.028 13.7 0.0 1.2 8.4 0.0 2.4 2 0 0 2 2 2 0 WD40-like domain LisH PF08513.11 KIY64206.1 - 0.18 11.8 0.0 7.1 6.7 0.0 2.4 2 0 0 2 2 2 0 LisH DUF5423 PF17461.2 KIY64207.1 - 0.036 12.9 0.1 0.041 12.7 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5423) CoatB PF10389.9 KIY64208.1 - 0.8 9.6 3.3 2 8.3 3.3 1.7 1 0 0 1 1 1 0 Bacteriophage coat protein B Meth_synt_2 PF01717.18 KIY64209.1 - 1e-15 57.9 0.0 3.2e-14 52.9 0.0 2.7 1 1 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 KIY64209.1 - 0.1 12.1 0.0 0.23 10.9 0.0 1.5 2 0 0 2 2 2 0 Cobalamin-independent synthase, N-terminal domain Ribosomal_L13e PF01294.18 KIY64210.1 - 5.3e-76 254.5 5.6 7.6e-76 254.0 5.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e zf-C2H2_4 PF13894.6 KIY64211.1 - 1.3e-05 25.6 2.9 0.17 12.8 0.6 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KIY64211.1 - 2.1e-05 24.7 1.2 5.4e-05 23.4 1.2 1.7 1 0 0 1 1 1 1 C2H2-type zinc ribbon zf-C2H2 PF00096.26 KIY64211.1 - 3.2e-05 24.1 5.7 0.074 13.5 0.9 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KIY64211.1 - 0.0092 16.4 0.3 0.0092 16.4 0.3 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-met PF12874.7 KIY64211.1 - 0.2 12.1 1.8 4.8 7.7 0.4 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KIY64211.1 - 0.26 11.7 1.9 0.97 9.8 1.8 1.9 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) p31comet PF06581.12 KIY64212.1 - 0.01 15.0 0.0 0.017 14.3 0.0 1.3 1 0 0 1 1 1 0 Mad1 and Cdc20-bound-Mad2 binding Zip PF02535.22 KIY64212.1 - 0.26 10.5 2.3 0.4 9.9 2.3 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Hid1 PF12722.7 KIY64212.1 - 2.3 6.2 3.8 3.9 5.5 3.8 1.4 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Mito_carr PF00153.27 KIY64213.1 - 3.3e-56 187.2 6.3 1.2e-23 82.8 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein PINIT PF14324.6 KIY64214.1 - 4.7e-39 134.0 3.0 7.5e-39 133.4 3.0 1.3 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.20 KIY64214.1 - 3.3e-19 68.4 7.8 6.2e-19 67.5 7.8 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 KIY64214.1 - 3.7e-08 33.0 2.3 3.7e-08 33.0 2.3 1.8 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit Rad50_zn_hook PF04423.14 KIY64214.1 - 0.13 12.1 0.0 2.4 8.1 0.0 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif CS PF04969.16 KIY64215.1 - 1.6e-16 61.1 0.2 3.2e-16 60.1 0.0 1.6 2 0 0 2 2 2 1 CS domain RWP-RK PF02042.15 KIY64217.1 - 3.7e-06 26.8 0.1 73 3.5 0.0 6.7 6 1 1 7 7 7 0 RWP-RK domain DDE_Tnp_ISAZ013 PF07592.11 KIY64217.1 - 4.6e-06 25.8 4.9 0.75 8.7 0.0 4.8 1 1 3 5 5 5 4 Rhodopirellula transposase DDE domain Sorb PF02208.16 KIY64217.1 - 1.5e-05 24.7 0.8 69 3.4 0.0 7.2 8 0 0 8 8 8 0 Sorbin homologous domain OTCace_N PF02729.21 KIY64217.1 - 3.8e-05 23.7 1.7 4.7 7.2 0.1 4.1 1 1 1 4 4 4 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain SAM_KSR1 PF13543.6 KIY64217.1 - 0.00021 21.5 0.0 8.9 6.5 0.0 4.8 1 1 4 6 6 6 1 SAM like domain present in kinase suppressor RAS 1 Uds1 PF15456.6 KIY64217.1 - 0.011 16.0 0.8 40 4.4 0.1 4.4 1 1 2 3 3 3 0 Up-regulated During Septation DUF1205 PF06722.12 KIY64217.1 - 0.17 12.0 5.9 1.1e+02 3.0 0.2 5.4 1 1 4 6 6 6 0 Protein of unknown function (DUF1205) ResIII PF04851.15 KIY64218.1 - 1e-22 81.0 0.0 2e-22 80.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KIY64218.1 - 1.7e-16 60.5 0.0 3.3e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIY64218.1 - 6e-16 58.8 0.0 7.6e-15 55.2 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF2075 PF09848.9 KIY64218.1 - 4.4e-05 22.9 0.0 7.7e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) SWI2_SNF2 PF18766.1 KIY64218.1 - 0.00013 21.7 0.0 0.00024 20.9 0.0 1.4 1 0 0 1 1 1 1 SWI2/SNF2 ATPase AAA_22 PF13401.6 KIY64218.1 - 0.01 16.1 0.0 0.026 14.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 KIY64218.1 - 0.025 13.7 0.0 0.042 12.9 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein DEAD_2 PF06733.15 KIY64218.1 - 0.045 13.4 0.0 0.093 12.3 0.0 1.4 1 0 0 1 1 1 0 DEAD_2 cobW PF02492.19 KIY64218.1 - 0.11 12.1 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain zf-C2H2_4 PF13894.6 KIY64219.1 - 7e-05 23.3 3.3 0.02 15.7 1.8 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.12 KIY64219.1 - 0.002 18.3 0.1 0.0035 17.6 0.1 1.3 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.26 KIY64219.1 - 0.0066 16.8 4.6 0.025 15.0 2.2 2.3 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-met PF12874.7 KIY64219.1 - 0.098 13.1 0.1 14 6.2 0.2 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Elf1 PF05129.13 KIY64219.1 - 0.19 11.8 1.0 0.45 10.6 1.0 1.6 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zf-H2C2_2 PF13465.6 KIY64219.1 - 0.23 12.0 5.6 3.9 8.1 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2 PF00096.26 KIY64221.1 - 3.2e-05 24.2 4.5 0.017 15.6 0.4 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIY64221.1 - 0.65 11.0 6.0 15 6.8 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger Indigoidine_A PF04227.12 KIY64223.1 - 3.6e-122 407.3 1.0 1.3e-121 405.4 0.0 2.1 2 0 0 2 2 2 1 Indigoidine synthase A like protein PfkB PF00294.24 KIY64223.1 - 1.1e-20 74.2 0.9 2.6e-11 43.4 0.0 3.0 2 1 0 2 2 2 2 pfkB family carbohydrate kinase MoaE PF02391.17 KIY64224.1 - 1.4e-39 134.8 0.1 1.7e-39 134.6 0.1 1.1 1 0 0 1 1 1 1 MoaE protein HutP PF09021.11 KIY64224.1 - 0.018 15.4 0.2 0.024 15.0 0.2 1.2 1 0 0 1 1 1 0 HutP Ion_trans PF00520.31 KIY64226.1 - 2.9e-07 30.0 0.9 3.7e-07 29.6 0.9 1.1 1 0 0 1 1 1 1 Ion transport protein Asp_protease_2 PF13650.6 KIY64227.1 - 0.048 14.3 0.0 0.095 13.4 0.0 1.5 2 0 0 2 2 2 0 Aspartyl protease PsaX PF08078.12 KIY64230.1 - 0.57 10.2 2.9 1.1 9.2 2.9 1.4 1 0 0 1 1 1 0 PsaX family HEAT PF02985.22 KIY64231.1 - 7.3e-15 53.8 7.1 0.3 11.5 0.0 7.6 8 0 0 8 8 8 5 HEAT repeat HEAT_2 PF13646.6 KIY64231.1 - 1.1e-08 35.3 11.5 0.038 14.4 0.0 6.6 4 3 2 6 6 6 3 HEAT repeats Cnd1 PF12717.7 KIY64231.1 - 2e-06 27.9 0.0 1.1 9.2 0.0 5.2 5 1 1 6 6 6 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KIY64231.1 - 0.00011 22.6 7.3 0.033 14.7 0.1 4.9 4 0 0 4 4 4 1 HEAT-like repeat Adaptin_N PF01602.20 KIY64231.1 - 0.32 9.5 0.0 1.1 7.7 0.0 1.8 2 0 0 2 2 2 0 Adaptin N terminal region Glyco_hydro_43 PF04616.14 KIY64232.1 - 7e-10 38.7 1.2 1.3e-09 37.8 1.2 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 Ribosom_S30AE_C PF16321.5 KIY64232.1 - 0.23 11.2 0.7 1.9 8.3 0.0 2.6 3 0 0 3 3 3 0 Sigma 54 modulation/S30EA ribosomal protein C terminus Asn_synthase PF00733.21 KIY64233.1 - 3.9e-95 319.5 0.0 1.4e-91 307.8 0.0 2.1 1 1 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 KIY64233.1 - 5.6e-36 123.2 0.0 9.2e-36 122.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KIY64233.1 - 4.6e-29 101.3 0.0 8.5e-29 100.5 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain NAD_synthase PF02540.17 KIY64233.1 - 0.02 14.0 0.0 0.042 13.0 0.0 1.4 1 0 0 1 1 1 0 NAD synthase CDP-OH_P_transf PF01066.21 KIY64234.1 - 7.6e-12 45.8 0.1 7.6e-12 45.8 0.1 2.3 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase SLATT_5 PF18160.1 KIY64234.1 - 0.0076 15.6 0.3 0.013 14.9 0.3 1.3 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain family 5 AAA PF00004.29 KIY64235.1 - 4.9e-35 120.8 0.0 1.1e-34 119.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KIY64235.1 - 9.6e-12 44.5 0.0 3.4e-11 42.8 0.0 2.0 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KIY64235.1 - 0.00025 21.5 0.3 0.02 15.3 0.0 3.4 2 1 0 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 KIY64235.1 - 0.00089 19.3 0.0 0.0037 17.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KIY64235.1 - 0.0018 18.5 0.1 0.036 14.3 0.0 3.0 2 1 1 3 3 3 1 AAA domain AAA_18 PF13238.6 KIY64235.1 - 0.0048 17.5 0.2 0.028 15.0 0.0 2.3 3 0 0 3 3 2 1 AAA domain AAA_11 PF13086.6 KIY64235.1 - 0.015 15.1 0.0 0.047 13.5 0.0 1.8 2 1 0 2 2 1 0 AAA domain Mg_chelatase PF01078.21 KIY64235.1 - 0.019 14.4 0.1 0.058 12.8 0.1 1.8 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 KIY64235.1 - 0.021 14.5 0.4 0.17 11.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KIY64235.1 - 0.029 14.5 0.0 0.11 12.7 0.0 2.0 2 0 0 2 2 1 0 AAA domain IstB_IS21 PF01695.17 KIY64235.1 - 0.03 14.0 0.1 0.1 12.3 0.0 1.9 2 0 0 2 2 1 0 IstB-like ATP binding protein Rad17 PF03215.15 KIY64235.1 - 0.031 14.2 0.0 0.055 13.4 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain RuvB_N PF05496.12 KIY64235.1 - 0.042 13.6 0.0 0.083 12.6 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_19 PF13245.6 KIY64235.1 - 0.043 14.2 0.1 0.15 12.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KIY64235.1 - 0.049 13.4 0.0 0.19 11.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_6 PF12774.7 KIY64235.1 - 0.051 12.5 0.0 0.092 11.7 0.0 1.3 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region AAA_28 PF13521.6 KIY64235.1 - 0.051 13.8 0.0 0.15 12.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 KIY64235.1 - 0.076 12.2 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_2 PF07724.14 KIY64235.1 - 0.1 12.7 0.0 0.28 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) TniB PF05621.11 KIY64235.1 - 0.12 11.8 0.0 6.6 6.1 0.0 3.0 2 1 1 3 3 3 0 Bacterial TniB protein RNA_helicase PF00910.22 KIY64235.1 - 0.15 12.4 0.0 0.5 10.8 0.0 1.9 2 0 0 2 2 1 0 RNA helicase AAA_7 PF12775.7 KIY64235.1 - 0.19 11.2 0.0 0.4 10.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF815 PF05673.13 KIY64235.1 - 0.21 10.7 0.0 0.33 10.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) SMC_Nse1 PF07574.13 KIY64236.1 - 1.9e-29 102.9 0.6 1.9e-29 102.9 0.6 2.9 2 2 0 2 2 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.11 KIY64236.1 - 1.9e-12 47.3 12.5 2e-11 44.0 12.0 2.2 2 0 0 2 2 2 1 RING-like domain zf-RING_2 PF13639.6 KIY64236.1 - 0.0021 18.3 9.5 0.0021 18.3 9.5 1.8 2 0 0 2 2 2 1 Ring finger domain C1_1 PF00130.22 KIY64236.1 - 0.18 11.8 13.3 0.54 10.2 8.6 2.7 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PPP4R2 PF09184.11 KIY64236.1 - 0.22 11.0 21.8 0.33 10.5 21.8 1.2 1 0 0 1 1 1 0 PPP4R2 BSP_II PF05432.11 KIY64236.1 - 0.42 10.3 34.0 0.61 9.7 34.0 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) ANAPC15 PF15243.6 KIY64236.1 - 0.55 10.7 30.1 0.49 10.8 6.7 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 zf-RING_4 PF14570.6 KIY64236.1 - 0.97 9.3 6.0 2.8 7.8 6.0 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-UDP PF14569.6 KIY64236.1 - 2.3 8.4 7.6 0.24 11.5 1.5 2.5 2 0 0 2 2 2 0 Zinc-binding RING-finger zf-C3HC4_2 PF13923.6 KIY64236.1 - 2.3 8.1 11.0 1.1 9.2 8.5 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Neur_chan_memb PF02932.16 KIY64236.1 - 7.1 6.6 7.1 9.3 6.2 7.1 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PHD_2 PF13831.6 KIY64236.1 - 8.8 6.0 8.3 7.3 6.2 5.5 2.3 1 1 1 2 2 2 0 PHD-finger Rtf2 PF04641.12 KIY64236.1 - 9.5 5.5 26.9 46 3.3 26.9 2.0 1 1 0 1 1 1 0 Rtf2 RING-finger Abhydrolase_3 PF07859.13 KIY64237.1 - 1.4e-10 41.4 0.0 2.5e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Pmp3 PF01679.17 KIY64238.1 - 5.1e-25 87.4 9.3 5.7e-25 87.3 9.3 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator DUF1328 PF07043.13 KIY64238.1 - 0.035 14.3 0.3 0.07 13.4 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1328) SUR7 PF06687.12 KIY64240.1 - 2.7e-21 76.2 10.2 3.5e-21 75.8 10.2 1.1 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.6 KIY64240.1 - 2.7e-06 27.3 3.9 4e-06 26.7 3.8 1.3 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DUF4293 PF14126.6 KIY64240.1 - 0.63 10.3 6.2 5.5 7.2 6.2 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4293) FAD_binding_3 PF01494.19 KIY64241.1 - 6.6e-20 71.6 0.1 2.2e-19 69.9 0.1 1.9 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KIY64241.1 - 6.3e-06 26.3 0.4 1.6e-05 25.0 0.4 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KIY64241.1 - 1.3e-05 24.6 0.1 1.9e-05 24.1 0.1 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KIY64241.1 - 3e-05 23.2 0.2 4.3e-05 22.7 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KIY64241.1 - 0.0002 20.6 0.3 0.00032 19.9 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KIY64241.1 - 0.00054 19.7 0.0 0.00079 19.1 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 KIY64241.1 - 0.0018 17.5 1.4 0.0026 16.9 1.4 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 KIY64241.1 - 0.002 17.5 0.1 0.004 16.6 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KIY64241.1 - 0.0079 16.7 0.8 0.016 15.8 0.8 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KIY64241.1 - 0.029 13.7 0.3 0.057 12.7 0.3 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 KIY64241.1 - 0.039 12.6 0.5 0.057 12.1 0.5 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 KIY64241.1 - 0.09 12.0 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TAL_FSA PF00923.19 KIY64241.1 - 0.16 11.3 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Transaldolase/Fructose-6-phosphate aldolase PCMT PF01135.19 KIY64243.1 - 6.9e-72 241.6 0.0 7.9e-72 241.4 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 KIY64243.1 - 1.8e-05 24.6 0.0 3e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.10 KIY64243.1 - 2.5e-05 24.1 0.0 3.5e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_25 PF13649.6 KIY64243.1 - 6.1e-05 23.6 0.0 0.00013 22.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIY64243.1 - 0.00023 21.1 0.0 0.0003 20.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 KIY64243.1 - 0.001 19.1 0.0 0.0017 18.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KIY64243.1 - 0.002 17.7 0.0 0.0037 16.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 KIY64243.1 - 0.0031 17.0 0.0 0.013 14.9 0.0 1.8 1 1 1 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 KIY64243.1 - 0.0077 16.9 0.0 0.014 16.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIY64243.1 - 0.0078 15.6 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family GidB PF02527.15 KIY64243.1 - 0.013 14.9 0.0 0.023 14.0 0.0 1.5 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G RrnaAD PF00398.20 KIY64243.1 - 0.086 11.9 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase MetW PF07021.12 KIY64243.1 - 0.11 12.1 0.0 0.24 11.0 0.0 1.6 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW Perilipin PF03036.16 KIY64244.1 - 4.8e-08 32.4 14.9 9.1e-07 28.2 0.0 2.5 1 1 1 2 2 2 1 Perilipin family Apolipoprotein PF01442.18 KIY64244.1 - 9.4e-08 32.2 5.6 1.6e-07 31.4 4.2 1.9 2 1 0 2 2 2 1 Apolipoprotein A1/A4/E domain ApoLp-III PF07464.11 KIY64244.1 - 0.0019 18.3 14.0 0.024 14.7 3.7 3.1 2 1 1 3 3 3 2 Apolipophorin-III precursor (apoLp-III) DUF4088 PF13317.6 KIY64244.1 - 0.0054 16.3 4.7 0.83 9.2 0.0 2.9 2 2 1 3 3 3 2 Protein of unknown function (DUF4088) SF-assemblin PF06705.11 KIY64244.1 - 0.024 14.0 0.3 0.1 11.9 0.1 2.0 2 1 0 2 2 2 0 SF-assemblin/beta giardin Duffy_binding PF05424.11 KIY64244.1 - 0.027 14.5 0.1 0.043 13.9 0.1 1.3 1 0 0 1 1 1 0 Duffy binding domain Gp-FAR-1 PF05823.12 KIY64244.1 - 0.039 14.3 0.4 0.19 12.1 0.0 2.0 1 1 1 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Baculo_PEP_C PF04513.12 KIY64244.1 - 0.6 10.1 8.4 0.13 12.4 2.9 2.6 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Prominin PF05478.11 KIY64244.1 - 1.5 6.6 6.9 1.5 6.7 3.4 1.8 1 1 1 2 2 2 0 Prominin BORCS6 PF10157.9 KIY64244.1 - 3 8.1 11.1 0.53 10.5 1.5 2.5 1 1 1 2 2 2 0 BLOC-1-related complex sub-unit 6 PhoU_div PF01865.16 KIY64246.1 - 0.15 11.4 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF47 GMC_oxred_N PF00732.19 KIY64247.1 - 7.3e-52 176.6 0.0 1.1e-51 176.0 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIY64247.1 - 4.9e-31 108.2 0.0 9.2e-31 107.3 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KIY64247.1 - 2.4e-05 24.5 0.3 6.1e-05 23.2 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KIY64247.1 - 4.9e-05 22.7 0.2 0.00066 19.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KIY64247.1 - 0.0011 17.9 0.1 0.0019 17.1 0.1 1.3 1 0 0 1 1 1 1 Tryptophan halogenase Pyr_redox_3 PF13738.6 KIY64247.1 - 0.0011 18.3 0.2 0.0059 15.9 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KIY64247.1 - 0.0018 17.4 0.1 0.0027 16.8 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 KIY64247.1 - 0.0025 17.4 2.5 0.0051 16.5 2.5 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KIY64247.1 - 0.022 13.5 0.7 0.039 12.7 0.7 1.3 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_2 PF00890.24 KIY64247.1 - 0.041 13.0 3.9 0.07 12.2 3.9 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.6 KIY64247.1 - 0.15 12.0 0.8 0.4 10.6 0.8 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding Peptidase_C50 PF03568.17 KIY64248.1 - 6.3e-133 443.7 0.0 9.8e-133 443.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family C50 CHAT PF12770.7 KIY64248.1 - 0.00053 19.5 0.0 0.014 14.9 0.0 2.6 1 1 1 2 2 2 1 CHAT domain DASH_Dam1 PF08653.10 KIY64248.1 - 0.28 11.0 0.8 0.95 9.3 0.8 1.9 1 0 0 1 1 1 0 DASH complex subunit Dam1 TPR_MalT PF17874.1 KIY64248.1 - 1 8.7 14.6 0.0066 15.9 3.9 2.6 3 0 0 3 3 3 0 MalT-like TPR region CHAT PF12770.7 KIY64250.1 - 1.2e-38 133.2 0.1 2.5e-38 132.1 0.1 1.5 2 0 0 2 2 2 1 CHAT domain TPR_10 PF13374.6 KIY64250.1 - 4.4e-11 42.3 18.3 0.018 14.9 0.0 10.2 12 0 0 12 12 12 3 Tetratricopeptide repeat TPR_8 PF13181.6 KIY64250.1 - 4.4e-07 29.6 5.2 11 6.5 0.0 8.8 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_12 PF13424.6 KIY64250.1 - 5.6e-05 23.4 7.1 0.57 10.5 0.0 7.5 7 2 3 10 10 10 1 Tetratricopeptide repeat TPR_2 PF07719.17 KIY64250.1 - 0.00097 19.1 4.1 1.5e+02 2.8 0.0 8.2 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_17 PF13431.6 KIY64250.1 - 0.008 16.5 0.6 5.3 7.6 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 KIY64250.1 - 2 8.2 12.3 2.5 7.9 0.0 6.2 8 0 0 8 8 8 0 TPR repeat UBA2_C PF16195.5 KIY64251.1 - 8.7 7.1 6.9 17 6.2 1.2 2.5 1 1 1 2 2 2 0 SUMO-activating enzyme subunit 2 C-terminus DTHCT PF08070.11 KIY64252.1 - 0.4 11.4 7.5 1.1 10.1 7.5 1.7 1 0 0 1 1 1 0 DTHCT (NUC029) region Abhydrolase_1 PF00561.20 KIY64253.1 - 2.8e-10 40.3 0.1 4.7e-10 39.5 0.1 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIY64253.1 - 2.2e-08 35.0 7.1 2.5e-08 34.8 6.5 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIY64253.1 - 1.4e-05 24.5 0.1 3.1e-05 23.3 0.1 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DUF915 PF06028.11 KIY64253.1 - 0.21 10.9 0.0 0.33 10.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Aminotran_1_2 PF00155.21 KIY64257.1 - 3.6e-74 250.1 0.0 4.7e-74 249.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KIY64257.1 - 4.3e-05 22.2 0.0 9.3e-05 21.1 0.0 1.4 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KIY64257.1 - 6.5e-05 22.0 0.0 0.00013 21.1 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Pertussis_S1 PF02917.14 KIY64257.1 - 0.019 14.8 0.3 0.045 13.5 0.0 1.7 2 0 0 2 2 2 0 Pertussis toxin, subunit 1 Preseq_ALAS PF09029.10 KIY64257.1 - 0.13 12.8 8.8 1.8 9.1 8.8 2.4 1 1 0 1 1 1 0 5-aminolevulinate synthase presequence UQ_con PF00179.26 KIY64259.1 - 3.1e-50 169.5 0.0 3.7e-50 169.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KIY64259.1 - 7.1e-05 22.5 0.0 9e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KIY64259.1 - 0.073 13.4 0.0 0.088 13.1 0.0 1.4 1 1 0 1 1 1 0 RWD domain Pkinase_fungal PF17667.1 KIY64265.1 - 4.1e-07 29.1 0.4 6e-07 28.6 0.4 1.2 1 0 0 1 1 1 1 Fungal protein kinase MalM PF07148.12 KIY64265.1 - 0.17 11.7 0.0 0.25 11.1 0.0 1.2 1 0 0 1 1 1 0 Maltose operon periplasmic protein precursor (MalM) DUF3126 PF11324.8 KIY64269.1 - 0.033 14.0 0.8 0.11 12.4 0.8 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3126) DUF4611 PF15387.6 KIY64269.1 - 0.16 12.2 1.9 0.3 11.3 1.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Sigma70_r1_1 PF03979.14 KIY64269.1 - 0.2 11.7 3.4 0.81 9.8 2.6 2.0 2 0 0 2 2 2 0 Sigma-70 factor, region 1.1 DUF3126 PF11324.8 KIY64270.1 - 0.097 12.5 0.0 0.31 10.9 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3126) Fungal_trans PF04082.18 KIY64271.1 - 3.7e-14 52.4 0.0 4.9e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KIY64273.1 - 2.5e-08 33.9 10.4 0.00012 22.3 1.6 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIY64273.1 - 7.1e-05 23.3 9.8 0.027 15.3 1.9 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KIY64273.1 - 0.00013 22.2 3.8 0.00013 22.2 3.8 2.7 3 0 0 3 3 3 1 Zinc-finger double domain DUF5540 PF17694.1 KIY64273.1 - 0.0053 17.2 1.8 0.047 14.2 0.3 2.6 2 0 0 2 2 2 1 Family of unknown function (DUF5540) DUF3844 PF12955.7 KIY64273.1 - 0.15 12.2 0.5 0.29 11.3 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3844) zf-H2C2_5 PF13909.6 KIY64273.1 - 0.82 9.5 5.2 2.9 7.7 1.0 2.5 2 0 0 2 2 2 0 C2H2-type zinc-finger domain Fungal_trans PF04082.18 KIY64274.1 - 1.5e-19 70.1 0.0 2e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Nrap_D3 PF17404.2 KIY64275.1 - 0.093 12.8 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 Nrap protein domain 3 OPT PF03169.15 KIY64278.1 - 2.2e-188 627.7 58.7 2.6e-188 627.6 58.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein SBP_bac_6 PF13343.6 KIY64279.1 - 2.6e-14 53.3 0.3 3.7e-14 52.7 0.3 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 KIY64279.1 - 2.2e-06 27.6 0.2 2.8e-06 27.2 0.2 1.3 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein Rad60-SLD PF11976.8 KIY64280.1 - 2.1e-22 78.7 0.1 2.5e-22 78.5 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KIY64280.1 - 3.6e-13 49.0 0.1 4.2e-13 48.8 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin family BTB PF00651.31 KIY64281.1 - 4.9e-05 23.5 0.0 9.3e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Fe-ADH PF00465.19 KIY64283.1 - 1e-50 172.6 1.3 1.4e-46 159.0 1.2 2.1 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 KIY64283.1 - 2e-29 103.1 0.0 6e-28 98.2 0.0 2.1 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.20 KIY64283.1 - 0.00042 19.5 1.4 0.013 14.7 1.4 2.5 1 1 0 1 1 1 1 3-dehydroquinate synthase Nbs1_C PF08599.10 KIY64285.1 - 0.045 13.9 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 DNA damage repair protein Nbs1 Costars PF14705.6 KIY64286.1 - 7.7e-13 48.4 0.1 3.9e-12 46.1 0.1 1.8 1 1 0 1 1 1 1 Costars 2-Hacid_dh_C PF02826.19 KIY64287.1 - 8.3e-42 142.5 0.0 1.2e-41 142.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KIY64287.1 - 2.6e-25 88.6 0.0 3.3e-25 88.3 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain F420_oxidored PF03807.17 KIY64287.1 - 6.9e-07 29.8 0.0 1.4e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 KIY64287.1 - 0.00012 22.3 0.0 0.00023 21.4 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 KIY64287.1 - 0.033 14.3 0.0 0.055 13.5 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase IlvN PF07991.12 KIY64287.1 - 0.12 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain DpnII-MboI PF18742.1 KIY64288.1 - 0.16 11.6 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 REase_DpnII-MboI MULE PF10551.9 KIY64289.1 - 2.7e-05 24.5 0.0 0.00015 22.2 0.0 2.1 2 0 0 2 2 2 1 MULE transposase domain SplA PF11132.8 KIY64289.1 - 0.058 13.2 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator protein (SplA) Pkinase_fungal PF17667.1 KIY64291.1 - 5.5e-24 84.7 0.0 3.5e-16 59.0 0.0 3.6 4 0 0 4 4 4 3 Fungal protein kinase DUF3953 PF13129.6 KIY64293.1 - 0.21 11.4 0.9 0.53 10.1 0.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3953) DDE_3 PF13358.6 KIY64294.1 - 3.5e-06 26.9 1.3 0.065 13.0 0.5 3.3 2 1 0 2 2 2 2 DDE superfamily endonuclease APG6_N PF17675.1 KIY64295.1 - 0.0017 18.9 10.0 0.0017 18.9 10.0 1.7 2 0 0 2 2 2 1 Apg6 coiled-coil region HALZ PF02183.18 KIY64295.1 - 0.0018 18.4 0.6 0.0018 18.4 0.6 2.5 2 1 0 2 2 2 1 Homeobox associated leucine zipper YabA PF06156.13 KIY64295.1 - 0.017 15.8 2.3 0.017 15.8 2.3 2.3 1 1 1 2 2 2 0 Initiation control protein YabA Adaptin_binding PF10199.9 KIY64295.1 - 0.061 13.9 5.7 0.067 13.8 4.3 1.7 1 1 1 2 2 2 0 Alpha and gamma adaptin binding protein p34 FapA PF03961.13 KIY64295.1 - 0.34 9.5 4.7 0.44 9.1 4.7 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A UPF0242 PF06785.11 KIY64295.1 - 0.4 10.8 11.4 0.11 12.6 7.7 1.7 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Jnk-SapK_ap_N PF09744.9 KIY64295.1 - 0.71 10.1 17.3 3.1 8.0 17.2 1.9 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 ADIP PF11559.8 KIY64295.1 - 2.5 8.2 11.7 1.5 8.9 9.6 1.6 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF4407 PF14362.6 KIY64295.1 - 4.9 6.4 9.2 6.9 5.9 9.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) F-box-like PF12937.7 KIY64296.1 - 0.00053 19.8 5.8 0.00053 19.8 5.8 2.2 2 1 0 2 2 2 1 F-box-like PC-Esterase PF13839.6 KIY64297.1 - 4.1e-07 30.0 0.0 0.0092 15.8 0.0 2.5 2 1 0 2 2 2 2 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Pkinase PF00069.25 KIY64298.1 - 6.9e-59 199.3 0.0 1.2e-58 198.6 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY64298.1 - 1.8e-32 112.7 0.0 4.1e-32 111.5 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY64298.1 - 1.9e-10 40.5 0.0 2.6e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KIY64298.1 - 0.00093 18.8 0.1 0.0027 17.3 0.0 1.6 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 KIY64298.1 - 0.001 19.1 0.0 0.0014 18.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KIY64298.1 - 0.0011 18.4 0.0 0.0017 17.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KIY64298.1 - 0.0017 17.4 0.0 0.0029 16.6 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KIY64298.1 - 0.014 14.2 0.0 0.021 13.6 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase zf-CCCH PF00642.24 KIY64299.1 - 2.2e-06 27.4 2.3 3.4e-06 26.8 2.3 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KIY64299.1 - 3.3e-06 27.0 5.5 4.8e-06 26.4 5.5 1.2 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 KIY64299.1 - 0.00018 21.2 2.5 0.00025 20.7 2.5 1.2 1 0 0 1 1 1 1 CCCH-type zinc finger DUF2353 PF09789.9 KIY64299.1 - 0.039 13.3 19.0 0.053 12.9 19.0 1.2 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) Torus PF16131.5 KIY64299.1 - 0.086 13.5 1.5 0.19 12.4 0.7 2.1 1 1 0 1 1 1 0 Torus domain Trypan_PARP PF05887.11 KIY64299.1 - 0.11 12.4 7.7 0.28 11.1 5.8 2.2 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Clusterin PF01093.17 KIY64299.1 - 0.29 10.1 7.0 0.42 9.6 7.0 1.2 1 0 0 1 1 1 0 Clusterin Exonuc_VII_L PF02601.15 KIY64299.1 - 1.3 8.5 8.7 2 7.9 8.7 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Borrelia_P83 PF05262.11 KIY64299.1 - 3.8 5.9 19.6 4.7 5.6 19.6 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein F-box-like PF12937.7 KIY64300.1 - 0.00011 22.0 6.9 0.00019 21.3 4.6 2.6 2 1 0 2 2 2 1 F-box-like Creatinase_N_2 PF16189.5 KIY64302.1 - 9.2e-38 129.9 0.0 2.1e-37 128.7 0.0 1.6 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 KIY64302.1 - 1.3e-24 87.1 0.0 1.7e-24 86.7 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 KIY64302.1 - 1.7e-14 53.6 0.0 3.7e-14 52.5 0.0 1.6 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 KIY64302.1 - 2.3e-13 51.0 0.0 4.3e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain F-box-like PF12937.7 KIY64304.1 - 3.4e-07 30.1 4.5 1.4e-06 28.0 4.5 1.9 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KIY64304.1 - 0.0022 17.8 1.1 0.22 11.5 1.5 2.5 2 0 0 2 2 2 2 F-box domain IHABP4_N PF16174.5 KIY64305.1 - 0.025 15.2 2.0 0.078 13.6 2.0 1.8 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal SPR1 PF15356.6 KIY64305.1 - 2.9 8.4 16.1 2.9 8.4 0.4 3.3 1 1 2 3 3 3 0 Psoriasis susceptibility locus 2 F-box-like PF12937.7 KIY64306.1 - 8.4e-05 22.4 1.8 0.00038 20.3 1.8 2.1 1 1 0 1 1 1 1 F-box-like F-box-like PF12937.7 KIY64307.1 - 2.3e-05 24.2 2.3 2.3e-05 24.2 2.3 2.3 2 1 0 2 2 2 1 F-box-like F-box-like PF12937.7 KIY64308.1 - 2.3e-07 30.6 3.8 1.2e-06 28.3 3.8 2.2 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KIY64308.1 - 0.22 11.4 3.9 3.2 7.7 1.7 2.8 3 0 0 3 3 3 0 F-box domain zf_CCCH_4 PF18345.1 KIY64309.1 - 0.00012 22.1 8.0 0.00026 20.9 8.0 1.6 1 0 0 1 1 1 1 Zinc finger domain HALZ PF02183.18 KIY64309.1 - 0.0066 16.7 9.1 4.7 7.5 0.0 4.8 3 1 4 7 7 7 2 Homeobox associated leucine zipper zf-CCCH_4 PF18044.1 KIY64309.1 - 0.033 14.0 5.1 0.054 13.3 5.1 1.4 1 0 0 1 1 1 0 CCCH-type zinc finger zf-CCCH PF00642.24 KIY64309.1 - 0.18 11.7 4.2 0.33 10.9 4.2 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF745 PF05335.13 KIY64309.1 - 0.26 11.0 53.7 0.14 11.8 1.8 3.8 1 1 1 3 3 3 0 Protein of unknown function (DUF745) MscS_porin PF12795.7 KIY64309.1 - 0.31 10.6 46.6 0.23 11.0 12.6 3.3 2 1 1 3 3 3 0 Mechanosensitive ion channel porin domain COG5 PF10392.9 KIY64309.1 - 1.2 9.3 10.2 0.49 10.6 1.0 2.6 2 0 0 2 2 2 0 Golgi transport complex subunit 5 Alanine_zipper PF11839.8 KIY64309.1 - 8.1 6.9 64.8 1.9 8.9 8.1 5.2 3 1 2 5 5 5 0 Alanine-zipper, major outer membrane lipoprotein zf-MYND PF01753.18 KIY64311.1 - 5.7e-07 29.5 9.5 1.1e-06 28.6 9.5 1.5 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KIY64311.1 - 1.3 9.4 8.3 2.7 8.4 8.3 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding adh_short PF00106.25 KIY64312.1 - 6.9e-08 32.2 0.0 1.1e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIY64312.1 - 0.058 13.3 0.1 0.08 12.8 0.1 1.2 1 0 0 1 1 1 0 KR domain DUF3842 PF12953.7 KIY64312.1 - 0.11 12.8 0.3 0.19 12.1 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3842) Aldo_ket_red PF00248.21 KIY64313.1 - 1.2e-51 175.6 0.3 1.2e-49 169.1 0.3 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family HTH_7 PF02796.15 KIY64313.1 - 0.018 15.1 0.4 0.9 9.7 0.0 3.3 4 0 0 4 4 4 0 Helix-turn-helix domain of resolvase IF2_N PF04760.15 KIY64313.1 - 0.12 12.2 0.0 0.59 10.0 0.0 2.1 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region MSA_2 PF00985.17 KIY64315.1 - 0.83 10.0 11.9 0.76 10.1 0.7 2.3 2 1 0 2 2 2 0 Merozoite Surface Antigen 2 (MSA-2) family PH PF00169.29 KIY64316.1 - 7.2e-08 32.9 0.0 1.6e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 PH domain MBOAT_2 PF13813.6 KIY64317.1 - 2.5e-15 56.5 3.0 2.5e-15 56.5 3.0 2.1 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family Rop-like PF05082.13 KIY64318.1 - 0.12 12.3 0.1 0.37 10.6 0.1 1.8 1 0 0 1 1 1 0 Rop-like F-box-like PF12937.7 KIY64319.1 - 0.14 12.1 0.8 0.29 11.1 0.8 1.6 1 0 0 1 1 1 0 F-box-like Cornichon PF03311.14 KIY64321.1 - 6.4e-52 175.0 10.2 7.4e-52 174.8 10.2 1.0 1 0 0 1 1 1 1 Cornichon protein Solute_trans_a PF03619.16 KIY64324.1 - 3.8e-86 288.9 16.6 4.7e-86 288.6 16.6 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF3262 PF11660.8 KIY64324.1 - 1.1 9.7 4.8 4.1 7.9 4.8 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3262) Dehydrin PF00257.19 KIY64325.1 - 0.018 15.6 0.0 0.024 15.2 0.0 1.1 1 0 0 1 1 1 0 Dehydrin Gpr1_Fun34_YaaH PF01184.19 KIY64328.1 - 7.2e-74 247.9 12.7 8.5e-74 247.6 12.7 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF3483 PF11982.8 KIY64328.1 - 0.27 10.9 0.1 0.27 10.9 0.1 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF3483) CPP1-like PF11833.8 KIY64329.1 - 5.5 6.6 7.9 1.9 8.1 1.9 2.2 1 1 1 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Rab3-GTPase_cat PF13890.6 KIY64330.1 - 0.034 13.8 0.1 0.034 13.8 0.1 2.1 2 0 0 2 2 2 0 Rab3 GTPase-activating protein catalytic subunit HEAT_EZ PF13513.6 KIY64331.1 - 4.8e-19 68.5 7.1 7.3e-08 32.8 0.0 7.0 5 1 2 7 7 6 4 HEAT-like repeat Importin_rep_4 PF18808.1 KIY64331.1 - 1.6e-14 53.9 2.3 1.8e-13 50.6 0.2 3.4 3 1 0 3 3 3 1 Importin repeat HEAT PF02985.22 KIY64331.1 - 4.8e-14 51.3 8.1 0.0029 17.7 0.0 8.1 8 0 0 8 8 8 3 HEAT repeat HEAT_2 PF13646.6 KIY64331.1 - 2.2e-11 44.0 2.5 4e-07 30.3 0.1 5.9 4 2 3 7 7 7 4 HEAT repeats Vac14_Fab1_bd PF12755.7 KIY64331.1 - 5.3e-11 43.0 0.0 4.6e-05 23.9 0.0 3.6 1 1 2 3 3 3 2 Vacuolar 14 Fab1-binding region DUF3385 PF11865.8 KIY64331.1 - 1.2e-06 28.5 0.1 0.15 12.0 0.0 3.8 2 1 2 4 4 4 2 Domain of unknown function (DUF3385) Cnd1 PF12717.7 KIY64331.1 - 2.1e-06 27.9 0.6 9.6e-05 22.5 0.1 2.8 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 KIY64331.1 - 5.1e-05 22.0 0.4 0.002 16.7 0.0 2.7 2 2 0 3 3 3 1 Adaptin N terminal region CLASP_N PF12348.8 KIY64331.1 - 0.00046 19.8 0.3 2.5 7.6 0.0 5.0 4 2 1 5 5 5 1 CLASP N terminal TIP120 PF08623.10 KIY64331.1 - 0.0015 18.3 0.1 2.7 7.8 0.0 3.4 3 0 0 3 3 3 1 TATA-binding protein interacting (TIP20) DUF4042 PF13251.6 KIY64331.1 - 0.0065 16.2 0.2 4.2 7.0 0.0 4.6 4 1 1 5 5 5 1 Domain of unknown function (DUF4042) Cnd3 PF12719.7 KIY64331.1 - 0.042 13.0 0.1 3.7 6.7 0.0 3.3 3 0 0 3 3 3 0 Nuclear condensing complex subunits, C-term domain Arm PF00514.23 KIY64331.1 - 0.06 13.4 0.8 5.7 7.1 0.0 3.5 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat MMS19_C PF12460.8 KIY64331.1 - 0.077 12.1 4.3 0.54 9.3 0.1 3.8 3 2 1 4 4 4 0 RNAPII transcription regulator C-terminal Cellulase PF00150.18 KIY64332.1 - 6.2e-18 65.2 0.7 1.2e-17 64.3 0.7 1.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) B12-binding PF02310.19 KIY64332.1 - 0.036 14.1 0.0 3.7 7.6 0.0 2.3 2 0 0 2 2 2 0 B12 binding domain Peptidase_M36 PF02128.15 KIY64333.1 - 6.5e-133 443.5 7.7 9.1e-133 443.0 7.7 1.2 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) XRCC1_N PF01834.16 KIY64333.1 - 0.14 12.2 0.1 0.32 11.0 0.1 1.5 1 0 0 1 1 1 0 XRCC1 N terminal domain DIM PF08194.12 KIY64333.1 - 0.14 12.4 1.0 0.32 11.2 1.0 1.6 1 0 0 1 1 1 0 DIM protein Peptidase_M4 PF01447.18 KIY64333.1 - 0.28 11.7 6.0 0.32 11.5 4.5 2.0 2 0 0 2 2 2 0 Thermolysin metallopeptidase, catalytic domain KduI PF04962.12 KIY64336.1 - 0.0019 17.5 0.0 0.0035 16.7 0.0 1.3 1 0 0 1 1 1 1 KduI/IolB family Sina PF03145.16 KIY64338.1 - 0.017 15.1 0.6 0.019 14.9 0.6 1.1 1 0 0 1 1 1 0 Seven in absentia protein family SKG6 PF08693.10 KIY64339.1 - 0.044 13.2 0.9 0.079 12.4 0.9 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Phage_holin_2_1 PF04971.12 KIY64339.1 - 0.11 12.6 0.1 0.21 11.6 0.1 1.4 1 0 0 1 1 1 0 Bacteriophage P21 holin S Adeno_E3_CR2 PF02439.15 KIY64339.1 - 0.12 12.1 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF4328 PF14219.6 KIY64339.1 - 0.14 11.7 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) F-box-like PF12937.7 KIY64342.1 - 1.9e-06 27.6 3.4 6.7e-06 25.9 3.4 2.0 1 1 0 1 1 1 1 F-box-like DUF4164 PF13747.6 KIY64342.1 - 0.0061 16.8 0.5 0.011 16.0 0.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4164) Metal_resist PF13801.6 KIY64342.1 - 0.083 13.1 1.6 11 6.2 1.6 2.2 2 0 0 2 2 2 0 Heavy-metal resistance F-box PF00646.33 KIY64342.1 - 0.1 12.5 1.1 3.1 7.8 1.8 2.9 2 0 0 2 2 2 0 F-box domain zf-C2H2_aberr PF17017.5 KIY64343.1 - 0.08 13.1 0.3 0.1 12.7 0.3 1.1 1 0 0 1 1 1 0 Aberrant zinc-finger Lipl32 PF12103.8 KIY64347.1 - 0.0029 17.3 0.0 0.0035 17.0 0.0 1.2 1 0 0 1 1 1 1 Surface lipoprotein of Spirochaetales order Baculo_PEP_C PF04513.12 KIY64348.1 - 0.0089 16.1 6.9 0.27 11.3 0.9 2.2 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus Baculo_PEP_C PF04513.12 KIY64349.1 - 0.00014 22.0 2.8 0.19 11.8 0.2 2.2 2 0 0 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1180 PF06679.12 KIY64351.1 - 0.015 15.7 0.1 0.027 14.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) GRP PF07172.11 KIY64351.1 - 0.064 13.9 0.0 0.11 13.2 0.0 1.4 1 0 0 1 1 1 0 Glycine rich protein family GMC_oxred_N PF00732.19 KIY64352.1 - 9.4e-50 169.7 0.0 1.4e-49 169.0 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIY64352.1 - 2.8e-28 99.3 0.1 5.7e-28 98.3 0.1 1.6 1 0 0 1 1 1 1 GMC oxidoreductase Ifi-6-16 PF06140.13 KIY64353.1 - 0.17 11.8 30.1 0.31 11.0 30.1 1.5 1 0 0 1 1 1 0 Interferon-induced 6-16 family Baculo_PEP_C PF04513.12 KIY64356.1 - 0.0027 17.7 4.4 0.057 13.5 4.1 2.1 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus CHDCT2 PF08074.11 KIY64356.1 - 0.13 12.5 0.1 0.52 10.5 0.1 1.9 1 1 1 2 2 2 0 CHDCT2 (NUC038) domain DNA_pol_phi PF04931.13 KIY64361.1 - 0.31 9.1 3.7 0.47 8.5 3.7 1.2 1 0 0 1 1 1 0 DNA polymerase phi SDA1 PF05285.12 KIY64361.1 - 1.4 8.3 7.9 0.08 12.4 2.6 1.5 2 0 0 2 2 2 0 SDA1 HemY_N PF07219.13 KIY64361.1 - 5.8 7.2 6.1 1.4 9.1 1.1 2.5 2 0 0 2 2 2 0 HemY protein N-terminus PPTA PF01239.22 KIY64362.1 - 1.6e-18 65.7 1.1 5.2e-08 32.4 0.1 2.8 3 0 0 3 3 3 2 Protein prenyltransferase alpha subunit repeat Plavaka PF18759.1 KIY64364.1 - 2.7e-35 122.2 0.0 4.6e-35 121.4 0.0 1.3 1 0 0 1 1 1 1 Plavaka transposase DNA_pol_A_exo1 PF01612.20 KIY64369.1 - 4.7e-14 52.5 0.0 1.4e-13 50.9 0.0 1.6 1 1 0 1 1 1 1 3'-5' exonuclease HALZ PF02183.18 KIY64370.1 - 0.01 16.0 3.3 0.011 15.9 1.0 2.1 1 1 1 2 2 2 0 Homeobox associated leucine zipper Ax_dynein_light PF10211.9 KIY64370.1 - 0.036 14.0 2.9 0.048 13.6 1.7 1.7 1 1 0 1 1 1 0 Axonemal dynein light chain YabA PF06156.13 KIY64370.1 - 0.041 14.5 6.6 0.097 13.3 6.6 1.6 1 0 0 1 1 1 0 Initiation control protein YabA KASH_CCD PF14662.6 KIY64370.1 - 0.064 13.1 6.6 0.11 12.3 6.6 1.3 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH GrpE PF01025.19 KIY64370.1 - 0.073 12.7 1.7 46 3.6 5.6 2.8 2 1 0 2 2 2 0 GrpE Cortex-I_coil PF09304.10 KIY64370.1 - 0.08 13.2 3.3 0.18 12.1 3.3 1.6 1 0 0 1 1 1 0 Cortexillin I, coiled coil DivIC PF04977.15 KIY64370.1 - 0.089 12.6 1.8 0.2 11.4 1.2 1.9 1 1 0 1 1 1 0 Septum formation initiator TSC22 PF01166.18 KIY64370.1 - 0.19 12.1 5.0 5.6 7.4 0.1 2.6 1 1 1 2 2 2 0 TSC-22/dip/bun family Cnn_1N PF07989.11 KIY64370.1 - 0.23 11.7 6.2 0.17 12.0 3.9 1.9 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 GIT_CC PF16559.5 KIY64370.1 - 0.49 10.3 5.3 0.25 11.2 1.3 2.6 2 1 1 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor Spc7 PF08317.11 KIY64373.1 - 0.025 13.4 13.5 0.055 12.3 13.1 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein Fez1 PF06818.15 KIY64373.1 - 0.03 14.8 13.1 0.029 14.8 11.8 1.5 1 1 0 1 1 1 0 Fez1 TMPIT PF07851.13 KIY64373.1 - 1.2 8.3 6.2 2 7.6 6.2 1.3 1 0 0 1 1 1 0 TMPIT-like protein ATG16 PF08614.11 KIY64373.1 - 1.8 8.8 20.5 3 8.0 20.5 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Fib_alpha PF08702.10 KIY64373.1 - 4.6 7.4 11.0 2.4 8.3 4.2 2.4 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family V_ATPase_I PF01496.19 KIY64373.1 - 4.9 5.0 9.8 7.3 4.4 9.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2408 PF10303.9 KIY64373.1 - 5.9 7.4 10.7 5.2 7.6 1.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) Tli4_N PF18443.1 KIY64374.1 - 0.024 15.0 4.3 1.9 8.9 4.3 2.5 1 1 0 1 1 1 0 Tle cognate immunity protein 4 N-terminal domain 3A PF00803.18 KIY64374.1 - 0.065 12.5 0.5 0.16 11.3 0.5 1.6 1 0 0 1 1 1 0 3A/RNA2 movement protein family IL32 PF15225.6 KIY64374.1 - 0.066 13.6 1.1 0.17 12.3 1.1 1.6 1 0 0 1 1 1 0 Interleukin 32 IF-2B PF01008.17 KIY64374.1 - 0.097 11.9 0.7 1 8.5 0.0 2.2 2 0 0 2 2 2 0 Initiation factor 2 subunit family DUF1451 PF07295.11 KIY64374.1 - 3.1 7.8 8.5 1.3 9.1 0.8 2.2 1 1 1 2 2 2 0 Zinc-ribbon containing domain TFIIA PF03153.13 KIY64374.1 - 9.4 6.1 14.6 12 5.8 14.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ABC2_membrane PF01061.24 KIY64375.1 - 2e-84 282.2 58.4 7.7e-44 149.6 24.0 2.9 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KIY64375.1 - 1.9e-38 132.0 0.0 2.6e-18 66.9 0.0 2.8 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.12 KIY64375.1 - 9e-32 108.8 0.1 9e-32 108.8 0.1 3.6 4 0 0 4 4 2 2 CDR ABC transporter ABC_trans_N PF14510.6 KIY64375.1 - 1.8e-18 66.9 0.0 1.2e-17 64.3 0.0 2.4 2 0 0 2 2 2 1 ABC-transporter N-terminal AAA_25 PF13481.6 KIY64375.1 - 4.2e-07 29.7 1.4 3.2e-06 26.8 0.2 2.6 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KIY64375.1 - 6.5e-07 29.9 0.3 0.003 17.9 0.1 2.5 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KIY64375.1 - 3.5e-05 23.8 0.0 0.0027 17.6 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_33 PF13671.6 KIY64375.1 - 0.00012 22.3 0.1 0.07 13.3 0.1 2.6 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KIY64375.1 - 0.00016 21.6 0.0 0.31 10.8 0.0 3.0 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 KIY64375.1 - 0.00027 21.5 0.0 0.013 16.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KIY64375.1 - 0.00043 20.0 0.4 0.012 15.3 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 KIY64375.1 - 0.00055 20.2 0.1 0.93 9.8 0.0 3.3 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 KIY64375.1 - 0.0015 18.4 0.1 1.2 9.0 0.0 2.7 2 0 0 2 2 2 2 NACHT domain SMC_N PF02463.19 KIY64375.1 - 0.0041 16.6 0.0 0.37 10.2 0.0 2.9 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain cobW PF02492.19 KIY64375.1 - 0.0043 16.7 1.1 0.5 9.9 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 KIY64375.1 - 0.0051 17.1 0.1 0.24 11.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KIY64375.1 - 0.0084 15.8 0.5 1.8 8.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 KIY64375.1 - 0.036 14.5 0.6 1 9.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KIY64375.1 - 0.07 13.6 0.0 18 5.8 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 KIY64375.1 - 0.1 13.1 0.0 0.26 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain PDR_assoc PF08370.11 KIY64375.1 - 0.29 10.9 6.2 0.68 9.7 0.4 3.6 3 0 0 3 3 3 0 Plant PDR ABC transporter associated ABC2_membrane_3 PF12698.7 KIY64375.1 - 8.1 5.5 45.5 2.6 7.0 20.4 3.0 2 1 0 2 2 2 0 ABC-2 family transporter protein SMC_N PF02463.19 KIY64376.1 - 2.8e-20 72.7 3.0 1.1e-19 70.8 3.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KIY64376.1 - 1.4e-10 42.0 31.2 1.4e-10 42.0 31.2 6.2 2 2 0 2 2 2 1 AAA domain AAA_15 PF13175.6 KIY64376.1 - 9.9e-06 25.5 0.1 9.9e-06 25.5 0.1 3.8 3 1 0 3 3 3 1 AAA ATPase domain AAA_29 PF13555.6 KIY64376.1 - 0.00019 21.1 0.0 0.00073 19.2 0.0 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.6 KIY64376.1 - 0.027 14.3 0.2 0.027 14.3 0.2 3.5 4 1 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 KIY64376.1 - 0.055 13.9 0.2 0.46 10.9 0.1 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 KIY64376.1 - 0.14 12.7 0.1 0.14 12.7 0.1 5.2 4 1 0 4 4 4 0 ABC transporter Avidin PF01382.17 KIY64377.1 - 9.6e-23 80.9 2.6 1.2e-22 80.5 2.6 1.1 1 0 0 1 1 1 1 Avidin family Cupin_3 PF05899.12 KIY64377.1 - 0.049 13.3 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF861) MBOAT_2 PF13813.6 KIY64378.1 - 2.4e-20 72.6 5.7 5.4e-20 71.5 5.7 1.6 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family p450 PF00067.22 KIY64381.1 - 1.2e-60 205.7 0.0 1.6e-60 205.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 peroxidase PF00141.23 KIY64382.1 - 5.5e-24 85.1 0.1 1e-23 84.3 0.1 1.4 1 0 0 1 1 1 1 Peroxidase DUF4799 PF16056.5 KIY64385.1 - 0.16 11.1 0.1 0.16 11.1 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4799) OPT PF03169.15 KIY64387.1 - 1.2e-170 569.2 52.5 1.4e-170 569.0 52.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein WD40 PF00400.32 KIY64388.1 - 2.1e-24 85.3 15.6 1.1e-05 26.1 0.0 7.2 7 1 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.8 KIY64388.1 - 4.1e-07 29.0 1.3 0.0029 16.3 0.0 3.5 3 1 1 4 4 4 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KIY64388.1 - 0.0041 17.4 0.0 8.4 6.8 0.0 4.0 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain S6OS1 PF15676.5 KIY64388.1 - 2.2 6.6 4.2 3.2 6.1 4.2 1.1 1 0 0 1 1 1 0 Six6 opposite strand transcript 1 family Glyco_transf_90 PF05686.12 KIY64389.1 - 2.6e-18 66.1 1.4 8.5e-18 64.4 0.5 2.3 2 1 0 2 2 2 1 Glycosyl transferase family 90 Ribosomal_S14 PF00253.21 KIY64390.1 - 2.3e-14 52.9 3.4 2.4e-14 52.8 3.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e PNGaseA PF12222.8 KIY64392.1 - 4.3e-112 375.2 0.1 5.5e-112 374.8 0.1 1.1 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A ADH_zinc_N PF00107.26 KIY64393.1 - 1.2e-28 99.6 0.4 1.9e-28 99.1 0.4 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KIY64393.1 - 8.1e-19 69.0 0.1 1.3e-18 68.3 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIY64393.1 - 3.1e-09 36.7 0.0 7.1e-09 35.5 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 KIY64393.1 - 0.00059 19.7 0.0 0.0014 18.5 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase S1-P1_nuclease PF02265.16 KIY64394.1 - 7.4e-60 202.9 0.0 1.6e-58 198.5 0.0 2.0 1 1 0 1 1 1 1 S1/P1 Nuclease Adeno_PX PF05829.12 KIY64394.1 - 0.47 10.4 1.3 0.85 9.5 1.3 1.4 1 0 0 1 1 1 0 Adenovirus late L2 mu core protein (Protein X) Atg14 PF10186.9 KIY64395.1 - 5e-16 58.7 0.0 9.9e-16 57.7 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 VPS38 PF17649.1 KIY64395.1 - 0.0049 15.8 1.5 4.7 6.0 0.1 3.5 4 0 0 4 4 4 2 Vacuolar protein sorting 38 DUF3552 PF12072.8 KIY64395.1 - 0.088 12.2 3.9 0.14 11.5 3.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Spc7 PF08317.11 KIY64395.1 - 0.14 11.0 0.8 0.23 10.3 0.8 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein PUF PF00806.19 KIY64396.1 - 1.4e-57 188.2 12.1 7.8e-08 31.6 0.0 8.6 9 0 0 9 9 9 8 Pumilio-family RNA binding repeat FtsL PF04999.13 KIY64397.1 - 4.4 7.4 5.4 15 5.7 0.0 2.5 3 0 0 3 3 3 0 Cell division protein FtsL DUF2023 PF09633.10 KIY64398.1 - 0.21 11.8 0.0 1.7 8.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2023) SURF4 PF02077.15 KIY64401.1 - 2.3e-91 306.1 9.3 2.7e-91 305.9 9.3 1.0 1 0 0 1 1 1 1 SURF4 family NMN_transporter PF04973.12 KIY64401.1 - 0.083 12.9 13.3 0.13 12.2 13.3 1.3 1 0 0 1 1 1 0 Nicotinamide mononucleotide transporter DoxX PF07681.12 KIY64401.1 - 3.7 8.2 22.4 1.1 9.9 3.9 3.3 2 1 1 3 3 3 0 DoxX DAO PF01266.24 KIY64403.1 - 2.7e-33 116.0 0.0 3.1e-33 115.8 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KIY64403.1 - 0.0042 17.3 1.2 0.082 13.1 0.7 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KIY64403.1 - 0.054 12.7 0.1 0.12 11.6 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NADH_dh_m_C1 PF15088.6 KIY64403.1 - 0.058 13.0 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial ApbA PF02558.16 KIY64403.1 - 0.068 12.8 0.4 0.16 11.6 0.3 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA FA_desaturase PF00487.24 KIY64404.1 - 1.8e-24 87.0 18.1 1.8e-24 87.0 18.1 1.6 1 1 1 2 2 2 1 Fatty acid desaturase Lipid_DES PF08557.10 KIY64404.1 - 3.1e-17 61.8 0.1 5.8e-17 60.9 0.1 1.5 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) NUC153 PF08159.12 KIY64405.1 - 3.3e-13 49.2 0.2 6.6e-13 48.2 0.2 1.5 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.32 KIY64405.1 - 0.0053 17.6 0.2 17 6.5 0.1 3.7 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY64405.1 - 0.04 14.2 0.0 0.11 12.8 0.0 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain YopD PF05844.12 KIY64405.1 - 1.5 7.8 4.2 0.23 10.4 0.2 1.6 2 0 0 2 2 2 0 YopD protein Tyrosinase PF00264.20 KIY64406.1 - 1.6e-16 61.3 6.2 3.5e-16 60.2 6.1 1.6 1 1 0 1 1 1 1 Common central domain of tyrosinase Gti1_Pac2 PF09729.9 KIY64407.1 - 4.5e-26 92.1 5.4 2e-24 86.7 0.0 2.8 2 1 0 3 3 3 2 Gti1/Pac2 family RAP1 PF07218.11 KIY64407.1 - 4.2 5.5 5.0 5.3 5.2 5.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF155 PF02582.14 KIY64408.1 - 4.4e-53 180.0 0.1 8.8e-53 179.0 0.1 1.5 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 GLE1 PF07817.13 KIY64409.1 - 4.8e-49 166.8 0.0 1e-48 165.8 0.0 1.5 1 0 0 1 1 1 1 GLE1-like protein Borrelia_P83 PF05262.11 KIY64409.1 - 1.3 7.5 36.2 1.8 7.0 36.2 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein Sec5 PF15469.6 KIY64410.1 - 4.9e-51 173.2 0.2 1.4e-50 171.8 0.2 1.9 1 0 0 1 1 1 1 Exocyst complex component Sec5 Vps51 PF08700.11 KIY64410.1 - 0.0069 16.4 0.6 0.026 14.6 0.0 2.4 2 0 0 2 2 2 1 Vps51/Vps67 YpM PF09144.10 KIY64410.1 - 0.17 12.1 0.2 0.45 10.7 0.1 1.7 2 0 0 2 2 2 0 Yersinia pseudo-tuberculosis mitogen Inhibitor_I66 PF16850.5 KIY64411.1 - 0.00021 21.2 0.0 0.0004 20.3 0.0 1.6 1 1 0 1 1 1 1 Peptidase inhibitor I66 Spatacsin_C PF14649.6 KIY64411.1 - 0.15 11.1 0.0 0.19 10.8 0.0 1.1 1 0 0 1 1 1 0 Spatacsin C-terminus NOA36 PF06524.12 KIY64412.1 - 0.25 10.6 11.1 0.28 10.5 11.1 1.1 1 0 0 1 1 1 0 NOA36 protein RNA_pol_3_Rpc31 PF11705.8 KIY64412.1 - 0.41 10.9 13.2 0.59 10.4 13.2 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Cwf_Cwc_15 PF04889.12 KIY64412.1 - 0.68 9.6 9.3 0.83 9.3 9.3 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF2457 PF10446.9 KIY64412.1 - 1 8.5 12.6 1.3 8.1 12.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PPP4R2 PF09184.11 KIY64412.1 - 1.7 8.1 10.2 2.5 7.6 10.2 1.3 1 0 0 1 1 1 0 PPP4R2 Nop14 PF04147.12 KIY64412.1 - 3.4 5.8 11.2 3.6 5.7 11.2 1.0 1 0 0 1 1 1 0 Nop14-like family ECR1_N PF14382.6 KIY64413.1 - 4.8e-17 61.5 0.1 1e-16 60.4 0.1 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 KIY64413.1 - 4.4e-15 55.8 0.2 7.9e-15 54.9 0.2 1.4 1 0 0 1 1 1 1 KH domain zf-4CXXC_R1 PF10497.9 KIY64414.1 - 1.5e-05 25.1 14.6 1.5e-05 25.1 14.6 1.7 2 0 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 F-box-like PF12937.7 KIY64415.1 - 8.5e-07 28.8 0.2 1.9e-06 27.6 0.2 1.7 1 0 0 1 1 1 1 F-box-like DUF3645 PF12359.8 KIY64416.1 - 3.2 7.2 6.6 15 5.1 1.0 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3645) Oxidored_FMN PF00724.20 KIY64417.1 - 3.5e-89 299.4 0.0 4e-89 299.2 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Yae1_N PF09811.9 KIY64418.1 - 7e-11 41.7 3.4 1.2e-10 40.9 3.4 1.4 1 0 0 1 1 1 1 Essential protein Yae1, N terminal FAM92 PF06730.11 KIY64418.1 - 0.0014 18.1 0.0 0.0019 17.6 0.0 1.1 1 0 0 1 1 1 1 FAM92 protein Aa_trans PF01490.18 KIY64419.1 - 4.9e-82 275.8 31.1 6.5e-82 275.4 31.1 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Oxidored_FMN PF00724.20 KIY64420.1 - 1.7e-101 339.9 0.0 2e-101 339.7 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Glycos_trans_3N PF02885.17 KIY64420.1 - 0.011 15.6 0.0 0.078 12.8 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase family, helical bundle domain Suc_Fer-like PF06999.12 KIY64421.1 - 2.6e-53 180.8 0.0 3.2e-53 180.5 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like YhfH PF14149.6 KIY64421.1 - 0.28 11.2 3.5 0.73 9.9 3.1 1.8 2 0 0 2 2 2 0 YhfH-like protein F-box-like PF12937.7 KIY64422.1 - 1.3e-07 31.4 4.4 1.5e-06 28.0 0.6 2.8 3 0 0 3 3 3 2 F-box-like AAA PF00004.29 KIY64424.1 - 3.9e-48 163.2 0.0 2.5e-41 141.2 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KIY64424.1 - 1.6e-10 40.6 0.0 5.3e-10 39.0 0.0 1.9 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KIY64424.1 - 7.7e-09 36.1 0.1 8.6e-05 23.0 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain IstB_IS21 PF01695.17 KIY64424.1 - 2.7e-07 30.5 0.0 1.2e-05 25.1 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.14 KIY64424.1 - 1.6e-05 25.1 0.0 3.7e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KIY64424.1 - 0.00042 20.3 0.6 0.0082 16.2 0.0 3.3 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KIY64424.1 - 0.00071 19.9 0.2 0.14 12.5 0.1 3.5 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KIY64424.1 - 0.0047 17.1 0.1 0.04 14.1 0.0 2.5 3 0 0 3 3 2 1 AAA domain AAA_18 PF13238.6 KIY64424.1 - 0.0061 17.1 0.0 0.17 12.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 KIY64424.1 - 0.012 15.3 0.0 0.25 11.1 0.0 3.0 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 KIY64424.1 - 0.014 14.9 0.0 0.71 9.4 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Bromodomain PF00439.25 KIY64424.1 - 0.016 15.2 0.0 0.035 14.2 0.0 1.5 1 0 0 1 1 1 0 Bromodomain AAA_30 PF13604.6 KIY64424.1 - 0.019 14.7 0.0 0.094 12.4 0.0 2.2 3 0 0 3 3 3 0 AAA domain Sigma54_activ_2 PF14532.6 KIY64424.1 - 0.021 15.0 0.0 2.8 8.0 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain RNA_helicase PF00910.22 KIY64424.1 - 0.025 15.0 0.0 0.12 12.7 0.0 2.1 2 0 0 2 2 2 0 RNA helicase AAA_28 PF13521.6 KIY64424.1 - 0.027 14.7 0.5 0.19 12.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KIY64424.1 - 0.029 13.8 0.2 0.15 11.5 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Torsin PF06309.11 KIY64424.1 - 0.039 14.1 0.0 0.87 9.7 0.0 2.3 2 0 0 2 2 2 0 Torsin AAA_25 PF13481.6 KIY64424.1 - 0.049 13.2 0.7 0.48 10.0 0.0 3.0 3 0 0 3 3 3 0 AAA domain Sigma54_activat PF00158.26 KIY64424.1 - 0.05 13.3 0.0 1.3 8.7 0.0 2.6 3 0 0 3 3 3 0 Sigma-54 interaction domain ABC_tran PF00005.27 KIY64424.1 - 0.059 13.9 0.0 0.27 11.8 0.0 2.1 1 0 0 1 1 1 0 ABC transporter PhoH PF02562.16 KIY64424.1 - 0.066 12.6 0.0 0.24 10.8 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein NACHT PF05729.12 KIY64424.1 - 0.094 12.6 0.1 0.32 10.9 0.0 2.0 2 0 0 2 2 1 0 NACHT domain TIP49 PF06068.13 KIY64424.1 - 0.13 11.5 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_11 PF13086.6 KIY64424.1 - 0.19 11.5 0.2 0.93 9.2 0.0 2.2 3 0 0 3 3 3 0 AAA domain AAA_14 PF13173.6 KIY64424.1 - 0.2 11.7 0.0 0.46 10.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 KIY64424.1 - 0.21 10.6 0.0 0.64 9.1 0.0 1.7 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 DUF3394 PF11874.8 KIY64424.1 - 0.21 11.2 0.0 0.39 10.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3394) DTHCT PF08070.11 KIY64424.1 - 2.5 8.9 18.7 0.084 13.6 3.3 3.4 3 0 0 3 3 2 0 DTHCT (NUC029) region Lipase_3 PF01764.25 KIY64425.1 - 1.8e-06 27.9 0.0 1.2e-05 25.3 0.0 1.9 1 1 1 2 2 2 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KIY64425.1 - 0.025 15.2 0.3 0.055 14.1 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase family Lipase PF00151.19 KIY64425.1 - 0.086 12.1 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Lipase PGAP1 PF07819.13 KIY64425.1 - 0.14 11.9 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein adh_short PF00106.25 KIY64426.1 - 1.5e-21 76.7 0.0 1.6e-19 70.2 0.1 2.1 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KIY64426.1 - 1.9e-13 50.6 0.0 4.9e-13 49.2 0.0 1.6 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIY64426.1 - 0.00015 21.7 0.1 0.00027 20.9 0.1 1.3 1 0 0 1 1 1 1 KR domain FAD_binding_4 PF01565.23 KIY64427.1 - 6.4e-28 97.2 1.5 9.7e-28 96.6 1.5 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KIY64427.1 - 0.086 13.0 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Berberine and berberine like zf-C2H2_8 PF15909.5 KIY64428.1 - 0.017 15.4 1.1 0.017 15.4 1.1 1.9 2 0 0 2 2 2 0 C2H2-type zinc ribbon zf-H2C2_2 PF13465.6 KIY64428.1 - 0.02 15.3 6.2 0.031 14.7 0.8 2.6 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2HC_2 PF13913.6 KIY64428.1 - 0.033 14.1 0.1 0.065 13.2 0.1 1.5 1 0 0 1 1 1 0 zinc-finger of a C2HC-type PyrI_C PF02748.15 KIY64428.1 - 0.092 12.7 0.7 0.16 11.9 0.7 1.3 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2 PF00096.26 KIY64428.1 - 0.15 12.6 0.2 0.15 12.6 0.2 2.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIY64428.1 - 0.35 11.8 8.9 0.43 11.6 0.9 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger GPR15L PF15854.5 KIY64428.1 - 3.2 8.0 4.9 5.9 7.2 4.9 1.3 1 0 0 1 1 1 0 G-protein coupled receptor ligand 15 Sugar_tr PF00083.24 KIY64429.1 - 3.4e-126 421.7 19.6 6.8e-126 420.7 19.6 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY64429.1 - 2.7e-16 59.4 34.1 1.3e-10 40.8 13.5 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2530 PF10745.9 KIY64429.1 - 1.6 9.0 7.9 0.15 12.4 0.6 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) SelK_SelG PF10961.8 KIY64429.1 - 2 9.1 8.2 60 4.3 0.1 4.6 5 0 0 5 5 5 0 Selenoprotein SelK_SelG ORF6C PF10552.9 KIY64431.1 - 0.017 15.2 0.0 0.026 14.6 0.0 1.2 1 0 0 1 1 1 0 ORF6C domain GalP_UDP_tr_C PF02744.17 KIY64431.1 - 0.031 14.0 0.0 0.041 13.6 0.0 1.1 1 0 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, C-terminal domain DUF3764 PF12594.8 KIY64431.1 - 0.051 13.6 0.0 0.084 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3764) NAD_binding_10 PF13460.6 KIY64432.1 - 2.7e-22 79.6 2.3 4.2e-22 78.9 2.3 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KIY64432.1 - 0.00025 20.6 0.0 0.00045 19.8 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KIY64432.1 - 0.00055 19.6 0.0 0.00084 19.0 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 KIY64432.1 - 0.067 12.6 0.1 0.16 11.4 0.1 1.6 1 1 1 2 2 2 0 short chain dehydrogenase Nucleoporin_FG PF13634.6 KIY64434.1 - 5e-36 123.4 163.0 6.3e-11 43.0 43.9 4.4 2 1 2 4 4 4 4 Nucleoporin FG repeat region Allexi_40kDa PF05549.11 KIY64434.1 - 0.071 12.6 1.9 0.13 11.8 1.9 1.3 1 0 0 1 1 1 0 Allexivirus 40kDa protein NmrA PF05368.13 KIY64435.1 - 1.1e-32 113.4 0.0 1.5e-32 113.1 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KIY64435.1 - 4.3e-14 52.8 0.0 1.9e-13 50.7 0.0 1.9 1 1 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KIY64435.1 - 1.4e-07 31.8 0.2 5.6e-07 29.9 0.1 1.8 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 KIY64435.1 - 2.9e-05 24.3 0.1 0.00018 21.8 0.1 2.0 2 0 0 2 2 2 1 TrkA-N domain 3Beta_HSD PF01073.19 KIY64435.1 - 7.2e-05 21.9 0.1 0.0001 21.4 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 KIY64435.1 - 0.00013 21.9 0.0 0.0002 21.3 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KIY64435.1 - 0.00022 20.8 0.1 0.00034 20.2 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 KIY64435.1 - 0.0014 19.1 0.1 0.0024 18.3 0.1 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 KIY64435.1 - 0.0071 15.6 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Shikimate_DH PF01488.20 KIY64435.1 - 0.031 14.3 0.1 0.13 12.3 0.0 2.0 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase adh_short PF00106.25 KIY64435.1 - 0.051 13.0 0.0 0.076 12.5 0.0 1.2 1 0 0 1 1 1 0 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 KIY64435.1 - 0.071 12.5 0.0 0.098 12.0 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase DapB_N PF01113.20 KIY64435.1 - 0.073 13.2 0.1 0.12 12.4 0.1 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Redoxin PF08534.10 KIY64437.1 - 4.9e-35 120.4 0.0 5.6e-35 120.2 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KIY64437.1 - 4e-12 46.1 0.0 4.4e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family HNH_2 PF13391.6 KIY64439.1 - 3.8e-05 23.7 0.1 7.2e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 HNH endonuclease TPR_9 PF13371.6 KIY64439.1 - 0.044 13.9 0.6 0.1 12.8 0.1 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Zn_ribbon_17 PF17120.5 KIY64439.1 - 0.41 10.3 2.3 0.3 10.7 0.2 1.9 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type FAD_binding_3 PF01494.19 KIY64441.1 - 3.6e-13 49.5 0.2 1.5e-12 47.5 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 KIY64441.1 - 0.00013 21.7 0.6 0.19 11.3 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIY64441.1 - 0.00043 19.6 0.9 0.012 14.8 0.4 2.1 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KIY64441.1 - 0.00058 18.7 0.7 0.038 12.7 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox PF00070.27 KIY64441.1 - 0.021 15.4 0.1 0.31 11.6 0.4 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GP67 PF17634.2 KIY64441.1 - 0.022 15.1 2.0 0.051 14.0 2.0 1.5 1 0 0 1 1 1 0 Gene product 67 Pyr_redox_3 PF13738.6 KIY64441.1 - 0.17 11.1 0.0 15 4.7 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PAC4 PF16093.5 KIY64442.1 - 2.5e-21 75.7 0.1 3.1e-21 75.3 0.1 1.1 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 Sde2_N_Ubi PF13019.6 KIY64444.1 - 0.19 11.5 0.0 0.39 10.5 0.0 1.4 1 0 0 1 1 1 0 Silencing defective 2 N-terminal ubiquitin domain HpcH_HpaI PF03328.14 KIY64446.1 - 6.7e-29 100.6 0.0 8.7e-29 100.2 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PK PF00224.21 KIY64446.1 - 0.00038 19.5 0.2 0.00056 18.9 0.2 1.2 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain zinc_ribbon_10 PF10058.9 KIY64447.1 - 2.9e-20 71.7 0.3 4.6e-20 71.1 0.3 1.3 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein Mu-like_Com PF10122.9 KIY64447.1 - 0.0054 16.2 0.1 0.0096 15.4 0.1 1.4 1 0 0 1 1 1 1 Mu-like prophage protein Com Zn-ribbon_8 PF09723.10 KIY64447.1 - 0.086 13.0 0.7 0.16 12.1 0.7 1.5 1 0 0 1 1 1 0 Zinc ribbon domain SMN PF06003.12 KIY64447.1 - 0.5 9.6 6.1 1.2 8.3 0.0 2.2 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) PhnA_Zn_Ribbon PF08274.12 KIY64447.1 - 2.3 8.2 4.7 12 6.0 4.8 1.9 1 1 1 2 2 2 0 PhnA Zinc-Ribbon Kdo_hydroxy PF11004.8 KIY64450.1 - 0.013 14.8 0.0 0.027 13.8 0.0 1.4 1 1 1 2 2 2 0 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase Baculo_PEP_C PF04513.12 KIY64451.1 - 9.3e-06 25.7 2.3 0.0038 17.3 0.4 2.1 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.11 KIY64451.1 - 0.033 14.4 5.2 0.15 12.3 1.6 2.3 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Dynamin_M PF01031.20 KIY64452.1 - 2.9e-105 351.6 0.0 6.9e-105 350.3 0.0 1.6 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 KIY64452.1 - 1.5e-55 187.8 0.0 7.4e-55 185.5 0.0 2.1 2 0 0 2 2 2 1 Dynamin family GED PF02212.18 KIY64452.1 - 3.1e-28 97.8 0.6 3.1e-28 97.8 0.6 1.9 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KIY64452.1 - 2.7e-05 24.2 0.0 0.00046 20.3 0.0 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase Sox17_18_mid PF12067.8 KIY64452.1 - 0.26 11.3 1.1 0.52 10.4 0.4 1.8 2 0 0 2 2 2 0 Sox 17/18 central domain RsgA_GTPase PF03193.16 KIY64452.1 - 1.2 9.0 4.5 13 5.6 0.0 3.7 4 0 0 4 4 4 0 RsgA GTPase Pkinase PF00069.25 KIY64454.1 - 0.00078 18.9 0.0 0.0016 17.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KIY64454.1 - 0.0046 16.9 2.5 0.013 15.4 1.9 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KIY64454.1 - 0.0082 15.5 0.1 0.015 14.7 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KIY64454.1 - 0.03 13.9 0.0 0.065 12.8 0.0 1.5 1 0 0 1 1 1 0 RIO1 family DUF3581 PF12119.8 KIY64454.1 - 0.039 13.4 0.0 0.28 10.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3581) WaaY PF06176.11 KIY64454.1 - 0.046 13.3 0.0 0.09 12.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Pkinase_Tyr PF07714.17 KIY64454.1 - 0.069 12.4 0.0 0.13 11.6 0.0 1.4 1 1 0 1 1 1 0 Protein tyrosine kinase GRDA PF04723.14 KIY64455.1 - 0.17 11.6 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 Glycine reductase complex selenoprotein A FKBP_C PF00254.28 KIY64456.1 - 5.3e-31 106.8 0.0 6.5e-31 106.5 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF3767 PF12597.8 KIY64460.1 - 2e-15 56.4 0.1 2.3e-15 56.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) Rhodanese PF00581.20 KIY64461.1 - 1.1e-07 32.3 0.0 1.5e-07 31.9 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain SL4P PF17618.2 KIY64461.1 - 0.053 13.6 0.0 0.14 12.2 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized Strongylid L4 protein Ribonuc_red_lgC PF02867.15 KIY64463.1 - 1.6e-182 607.7 0.0 2.1e-182 607.3 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 KIY64463.1 - 2.9e-23 81.7 1.7 3.3e-23 81.5 0.0 2.1 2 0 0 2 2 2 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 KIY64463.1 - 4.7e-15 55.9 1.1 7.6e-15 55.3 0.2 1.9 2 0 0 2 2 2 1 ATP cone domain Gal11_ABD1 PF18535.1 KIY64463.1 - 0.033 14.3 0.1 0.1 12.7 0.1 1.7 1 0 0 1 1 1 0 Gal11 activator-binding domain (ABD1) DUF2017 PF09438.10 KIY64463.1 - 0.13 12.2 0.7 0.25 11.2 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2017) ADH_zinc_N PF00107.26 KIY64464.1 - 7.3e-21 74.5 0.1 1.4e-20 73.6 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KIY64464.1 - 5.8e-06 26.2 0.0 1.1e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 KIY64464.1 - 0.016 16.2 0.0 0.027 15.5 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase zf-AN1 PF01428.16 KIY64466.1 - 5.1e-20 71.3 33.8 1.6e-10 40.9 8.9 2.8 3 0 0 3 3 3 2 AN1-like Zinc finger Transp_Tc5_C PF04236.15 KIY64466.1 - 0.0024 18.2 17.1 0.18 12.2 6.4 2.3 2 0 0 2 2 2 2 Tc5 transposase C-terminal domain Ribosomal_L35p PF01632.19 KIY64467.1 - 2.2e-17 63.3 10.3 2.6e-17 63.0 10.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L35 DUF4470 PF14737.6 KIY64468.1 - 3.4e-16 59.2 0.0 6.4e-16 58.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.18 KIY64468.1 - 7.5e-08 32.3 14.5 1.2e-07 31.7 14.5 1.4 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KIY64468.1 - 0.0031 17.8 12.5 0.0056 16.9 12.5 1.4 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding Chaperone_III PF07824.12 KIY64468.1 - 0.15 12.3 0.0 1.9 8.7 0.0 2.6 3 0 0 3 3 3 0 Type III secretion chaperone domain zf-HIT PF04438.16 KIY64468.1 - 2.4 8.1 7.6 4.4 7.3 7.6 1.4 1 0 0 1 1 1 0 HIT zinc finger adh_short PF00106.25 KIY64469.1 - 4.6e-22 78.4 0.1 1e-21 77.3 0.1 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIY64469.1 - 1.4e-09 37.9 0.1 2.1e-09 37.3 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIY64469.1 - 3.4e-05 23.8 0.0 5.2e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KIY64469.1 - 0.0066 15.6 0.0 0.0086 15.2 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DUF3666 PF12408.8 KIY64469.1 - 0.031 13.5 0.0 0.38 10.0 0.0 2.3 2 0 0 2 2 2 0 Ribose-5-phosphate isomerase Med18 PF09637.10 KIY64471.1 - 0.0088 15.9 0.0 0.021 14.7 0.0 1.5 1 1 1 2 2 2 1 Med18 protein Pyr_redox_2 PF07992.14 KIY64472.1 - 0.0025 17.1 0.0 0.061 12.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KIY64472.1 - 0.0048 16.3 0.0 0.011 15.1 0.0 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KIY64472.1 - 0.056 12.3 0.0 8.3 5.1 0.0 2.8 3 0 0 3 3 3 0 Tryptophan halogenase Dus PF01207.17 KIY64473.1 - 1.8e-71 240.8 0.0 2.3e-71 240.4 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) ThiG PF05690.14 KIY64473.1 - 2.6e-05 23.7 0.0 4.2e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG SOR_SNZ PF01680.17 KIY64473.1 - 0.0006 19.7 0.0 0.0056 16.5 0.0 2.1 1 1 1 2 2 2 1 SOR/SNZ family COesterase PF00135.28 KIY64475.1 - 3.2e-84 283.6 0.0 3.9e-84 283.4 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KIY64475.1 - 7.1e-08 32.6 0.7 6.3e-07 29.5 0.2 2.5 2 1 0 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.28 KIY64476.1 - 1.5e-79 268.3 0.0 1.7e-79 268.0 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KIY64476.1 - 0.0001 22.2 1.1 0.0027 17.6 0.8 2.7 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KIY64476.1 - 0.12 11.9 0.0 2.7 7.4 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family COesterase PF00135.28 KIY64477.1 - 2.3e-85 287.4 0.0 2.8e-85 287.2 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KIY64477.1 - 5.8e-08 32.9 0.2 8e-07 29.1 0.2 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KIY64477.1 - 0.038 13.5 0.1 0.065 12.7 0.1 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 KIY64477.1 - 0.29 9.9 0.0 1.4 7.7 0.0 1.8 2 0 0 2 2 2 0 Steryl acetyl hydrolase O-FucT PF10250.9 KIY64478.1 - 5e-10 39.6 0.0 8.3e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Rhodanese PF00581.20 KIY64479.1 - 5.5e-08 33.3 0.0 7.5e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain SL4P PF17618.2 KIY64479.1 - 0.014 15.4 0.0 0.15 12.2 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized Strongylid L4 protein DUF3767 PF12597.8 KIY64480.1 - 8.2e-15 54.5 0.1 9.7e-15 54.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) TPR_2 PF07719.17 KIY64482.1 - 2.9e-26 89.4 18.2 4.3e-05 23.3 0.4 8.7 9 0 0 9 9 8 7 Tetratricopeptide repeat TPR_1 PF00515.28 KIY64482.1 - 2.9e-24 83.8 11.7 0.00026 20.7 0.1 8.0 9 0 0 9 9 7 5 Tetratricopeptide repeat DnaJ PF00226.31 KIY64482.1 - 4.6e-21 74.7 0.3 1.1e-20 73.5 0.3 1.7 1 0 0 1 1 1 1 DnaJ domain TPR_11 PF13414.6 KIY64482.1 - 2.5e-19 68.7 9.8 2.1e-05 24.1 0.3 6.0 5 2 1 6 6 5 4 TPR repeat TPR_16 PF13432.6 KIY64482.1 - 3e-16 59.8 14.5 0.0021 18.7 0.6 6.2 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_9 PF13371.6 KIY64482.1 - 1.4e-15 57.1 6.4 8.8e-06 25.8 0.1 4.8 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 KIY64482.1 - 2.1e-12 47.4 15.2 0.015 15.8 0.6 7.1 4 3 2 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 KIY64482.1 - 4.6e-11 42.8 15.6 8.7e-05 22.7 0.2 6.0 4 3 2 6 6 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 KIY64482.1 - 4.5e-09 36.4 20.2 0.019 15.8 0.2 8.7 6 3 4 10 10 9 2 Tetratricopeptide repeat TPR_8 PF13181.6 KIY64482.1 - 1.5e-06 28.0 10.7 0.79 10.1 0.1 6.5 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 KIY64482.1 - 4.5e-05 23.2 11.7 1.3 9.0 0.0 6.4 6 1 1 7 7 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 KIY64482.1 - 4.6e-05 23.5 4.8 0.83 10.2 0.1 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat MIT PF04212.18 KIY64482.1 - 0.00011 22.2 8.3 0.67 10.1 0.3 4.9 5 1 1 6 6 5 2 MIT (microtubule interacting and transport) domain ANAPC3 PF12895.7 KIY64482.1 - 0.00046 20.3 4.8 0.21 11.8 0.6 4.5 4 1 1 5 5 4 1 Anaphase-promoting complex, cyclosome, subunit 3 Coatomer_E PF04733.14 KIY64482.1 - 0.0049 16.3 0.7 2 7.8 0.1 2.9 3 0 0 3 3 3 1 Coatomer epsilon subunit TPR_7 PF13176.6 KIY64482.1 - 0.0083 16.1 11.5 8.9 6.6 0.0 6.1 5 1 1 6 6 6 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 KIY64482.1 - 0.013 14.9 0.7 0.42 10.1 0.1 2.9 2 0 0 2 2 2 0 SHNi-TPR TPR_6 PF13174.6 KIY64482.1 - 0.021 15.4 10.9 22 6.0 0.1 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat ANAPC5 PF12862.7 KIY64482.1 - 0.03 14.4 0.9 19 5.4 0.0 3.3 4 0 0 4 4 3 0 Anaphase-promoting complex subunit 5 BTAD PF03704.17 KIY64482.1 - 0.095 13.1 9.6 1.3 9.5 0.8 4.1 3 2 0 3 3 3 0 Bacterial transcriptional activator domain ChAPs PF09295.10 KIY64482.1 - 0.24 10.4 0.2 6.6 5.6 0.3 2.1 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) DUF1690 PF07956.11 KIY64482.1 - 1.4 9.3 4.8 2.1 8.8 0.1 2.8 2 1 0 2 2 2 0 Protein of Unknown function (DUF1690) DUF5082 PF16888.5 KIY64482.1 - 3.1 8.1 7.1 4.7 7.5 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF5082) DUF4140 PF13600.6 KIY64482.1 - 3.5 8.1 5.5 21 5.6 0.1 3.2 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DOT1 PF08123.13 KIY64483.1 - 4e-64 215.9 0.0 5.1e-64 215.6 0.0 1.1 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_31 PF13847.6 KIY64483.1 - 0.087 12.6 0.0 0.2 11.4 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain CMAS PF02353.20 KIY64483.1 - 0.12 11.7 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase DnaJ_CXXCXGXG PF00684.19 KIY64484.1 - 7.8e-05 23.0 9.0 0.009 16.4 3.6 2.6 2 1 0 2 2 2 2 DnaJ central domain Zn_Tnp_IS91 PF14319.6 KIY64484.1 - 0.084 12.9 6.7 0.93 9.6 0.9 2.3 2 0 0 2 2 2 0 Transposase zinc-binding domain Ribosomal_S27e PF01667.17 KIY64484.1 - 0.22 11.3 2.2 0.56 10.0 0.1 2.5 3 0 0 3 3 3 0 Ribosomal protein S27 DUF5351 PF17302.2 KIY64484.1 - 0.46 10.7 6.6 1 9.6 2.2 2.8 2 1 0 2 2 2 0 Family of unknown function (DUF5351) TackOD1 PF18551.1 KIY64484.1 - 0.53 9.9 3.4 13 5.4 0.0 2.1 2 0 0 2 2 2 0 Thaumarchaeal output domain 1 Anti-TRAP PF15777.5 KIY64484.1 - 1.3 9.1 10.1 4.8 7.2 3.2 2.8 2 1 1 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein DZR PF12773.7 KIY64484.1 - 4.4 7.4 7.8 6.4 6.9 1.4 2.7 2 1 0 2 2 2 0 Double zinc ribbon zf-RING_5 PF14634.6 KIY64484.1 - 5.6 7.0 8.9 15 5.6 0.1 3.4 3 1 0 3 3 3 0 zinc-RING finger domain Glyco_hydro_18 PF00704.28 KIY64485.1 - 1.6e-20 74.1 3.6 5e-20 72.4 3.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_5_12 PF02839.14 KIY64485.1 - 1.3 9.8 10.5 0.064 13.9 3.4 2.7 2 0 0 2 2 2 0 Carbohydrate binding domain Pkinase PF00069.25 KIY64488.1 - 5.7e-73 245.5 0.0 6.6e-73 245.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY64488.1 - 4.5e-30 104.8 0.0 7.3e-30 104.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KIY64488.1 - 0.0042 16.1 0.1 0.046 12.7 0.1 2.0 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KIY64488.1 - 0.026 13.9 0.1 0.12 11.7 0.1 2.0 1 1 0 2 2 2 0 Kinase-like APH PF01636.23 KIY64488.1 - 0.11 12.4 0.3 0.44 10.4 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family GST_N_2 PF13409.6 KIY64489.1 - 1.4e-07 31.7 0.0 3.1e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KIY64489.1 - 1.1e-06 28.9 0.0 2e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KIY64489.1 - 1.7e-06 28.1 0.0 3e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KIY64489.1 - 9.7e-05 23.1 0.0 0.00059 20.5 0.0 2.2 1 1 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C PF00043.25 KIY64489.1 - 0.001 19.2 0.0 0.0016 18.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KIY64489.1 - 0.0022 18.0 0.0 0.0041 17.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 KIY64489.1 - 0.11 12.8 0.0 0.21 11.9 0.0 1.5 1 1 0 1 1 1 0 Outer mitochondrial membrane transport complex protein PAM2 PF07145.15 KIY64490.1 - 0.00072 19.1 6.9 0.059 13.1 0.4 3.6 3 0 0 3 3 3 2 Ataxin-2 C-terminal region CENP-F_leu_zip PF10473.9 KIY64490.1 - 0.13 12.3 53.8 0.074 13.1 12.1 5.4 4 1 1 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Sugar_tr PF00083.24 KIY64491.1 - 2.2e-126 422.4 16.4 2.5e-126 422.2 16.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY64491.1 - 2.1e-17 63.1 33.0 2.3e-13 49.8 15.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-MYND PF01753.18 KIY64492.1 - 6.9e-10 38.9 16.1 1.2e-09 38.1 16.1 1.4 1 0 0 1 1 1 1 MYND finger DUF4462 PF14692.6 KIY64492.1 - 0.081 12.4 0.2 0.35 10.4 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4462) GvpG PF05120.12 KIY64492.1 - 0.21 11.6 0.0 0.35 10.9 0.0 1.3 1 0 0 1 1 1 0 Gas vesicle protein G zf-C6H2 PF15801.5 KIY64492.1 - 0.55 10.6 11.5 1.3 9.4 11.5 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding BAR PF03114.18 KIY64494.1 - 3.4e-42 144.7 1.2 4.6e-42 144.3 1.2 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 KIY64494.1 - 5.1e-15 54.8 0.1 9.5e-15 53.9 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KIY64494.1 - 2.9e-13 49.4 0.1 4.8e-13 48.8 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KIY64494.1 - 2.1e-08 33.7 0.0 4.2e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Vps5 PF09325.10 KIY64494.1 - 0.025 14.2 0.9 0.093 12.3 0.5 1.9 2 0 0 2 2 2 0 Vps5 C terminal like DUF948 PF06103.11 KIY64494.1 - 0.11 12.7 0.1 2.6 8.3 0.0 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) ZZ PF00569.17 KIY64495.1 - 3e-10 39.8 2.6 5.2e-10 39.0 2.6 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type Apt1 PF10351.9 KIY64495.1 - 0.015 14.1 3.8 0.018 13.9 3.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Hid1 PF12722.7 KIY64495.1 - 1.8 6.6 4.4 2.2 6.3 4.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SPX PF03105.19 KIY64495.1 - 1.8 8.4 11.4 2.6 7.9 11.4 1.2 1 0 0 1 1 1 0 SPX domain Presenilin PF01080.17 KIY64495.1 - 7.3 5.2 6.3 10 4.8 6.3 1.1 1 0 0 1 1 1 0 Presenilin Zn_clus PF00172.18 KIY64496.1 - 1.5e-08 34.7 7.5 2.6e-08 33.9 7.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 KIY64497.1 - 0.0083 16.2 9.9 0.015 15.4 9.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Spore_YtrH PF14034.6 KIY64498.1 - 0.068 13.3 2.3 0.38 10.9 0.7 2.1 2 0 0 2 2 2 0 Sporulation protein YtrH DUF2613 PF11021.8 KIY64498.1 - 0.099 12.8 2.5 0.25 11.5 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) PsbI PF02532.14 KIY64498.1 - 0.11 12.4 0.0 0.29 11.1 0.0 1.7 1 0 0 1 1 1 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) MNHE PF01899.16 KIY64498.1 - 0.6 9.9 4.5 0.35 10.6 0.6 1.9 1 1 1 2 2 2 0 Na+/H+ ion antiporter subunit NapE PF06796.11 KIY64498.1 - 5.3 6.6 6.0 1.9 8.0 0.6 2.4 2 0 0 2 2 2 0 Periplasmic nitrate reductase protein NapE Oxysterol_BP PF01237.18 KIY64499.1 - 1.4e-83 280.8 0.1 2.1e-81 273.6 0.1 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein REV1_C PF16727.5 KIY64499.1 - 0.076 13.4 0.4 0.15 12.5 0.4 1.5 1 0 0 1 1 1 0 DNA repair protein REV1 C-terminal domain SMBP PF16785.5 KIY64499.1 - 0.12 12.6 0.2 0.21 11.8 0.2 1.3 1 0 0 1 1 1 0 Small metal-binding protein Zn_clus PF00172.18 KIY64500.1 - 0.048 13.8 9.8 0.71 10.1 3.4 2.3 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Anti-TRAP PF15777.5 KIY64500.1 - 0.62 10.1 3.9 1.3 9.1 3.9 1.5 1 0 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein Velvet PF11754.8 KIY64501.1 - 2.1e-18 67.2 0.0 1.5e-10 41.5 0.0 2.1 1 1 1 2 2 2 2 Velvet factor MDD_C PF18376.1 KIY64502.1 - 1.2e-73 246.8 0.1 1.6e-73 246.5 0.1 1.1 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 KIY64502.1 - 4.1e-07 30.1 3.6 7.2e-07 29.4 2.8 1.9 2 0 0 2 2 2 1 GHMP kinases N terminal domain SNF2_N PF00176.23 KIY64503.1 - 6.4e-70 235.6 0.1 1.7e-69 234.2 0.1 1.7 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KIY64503.1 - 2e-19 69.9 0.1 2.2e-18 66.6 0.0 2.8 4 0 0 4 4 4 1 Helicase conserved C-terminal domain HSA PF07529.13 KIY64503.1 - 9.1e-18 64.4 10.8 2.8e-17 62.8 10.8 1.9 1 0 0 1 1 1 1 HSA Bromodomain PF00439.25 KIY64503.1 - 3.9e-17 62.1 0.0 1.3e-16 60.4 0.0 1.9 1 0 0 1 1 1 1 Bromodomain SnAC PF14619.6 KIY64503.1 - 2e-09 37.9 0.5 2e-09 37.9 0.5 4.0 5 0 0 5 5 5 1 Snf2-ATP coupling, chromatin remodelling complex QLQ PF08880.11 KIY64503.1 - 2.2e-08 33.7 0.0 8.6e-08 31.8 0.0 2.1 1 0 0 1 1 1 1 QLQ ResIII PF04851.15 KIY64503.1 - 3e-07 30.6 0.0 1.3e-06 28.5 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KIY64503.1 - 1.6e-06 27.5 0.7 2.1e-05 23.9 0.0 2.4 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 DUF1965 PF09248.10 KIY64503.1 - 0.35 10.7 2.2 0.37 10.6 0.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1965) DBINO PF13892.6 KIY64503.1 - 3.8 7.9 17.8 0.31 11.4 12.3 2.0 2 0 0 2 2 2 0 DNA-binding domain Ku PF02735.16 KIY64504.1 - 3e-30 105.5 0.0 6e-30 104.5 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.11 KIY64504.1 - 5.9e-24 84.5 0.1 1.3e-23 83.4 0.1 1.6 1 0 0 1 1 1 1 Ku C terminal domain like Ku_N PF03731.15 KIY64504.1 - 5.2e-07 29.6 0.0 1.1e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 KIY64504.1 - 9.5e-05 23.0 0.1 9.5e-05 23.0 0.1 2.3 2 0 0 2 2 2 1 Ku70/Ku80 C-terminal arm VWA PF00092.28 KIY64504.1 - 0.00014 22.1 0.0 0.0017 18.6 0.0 2.5 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KIY64504.1 - 0.0014 19.2 0.0 0.0088 16.7 0.0 2.3 1 1 0 1 1 1 1 von Willebrand factor type A domain Nop10p PF04135.12 KIY64504.1 - 0.04 14.0 0.2 0.13 12.3 0.2 1.9 1 0 0 1 1 1 0 Nucleolar RNA-binding protein, Nop10p family Stealth_CR2 PF11380.8 KIY64505.1 - 7.3e-15 55.1 1.5 1.1e-09 38.4 0.2 2.7 1 1 1 2 2 2 2 Stealth protein CR2, conserved region 2 Stealth_CR1 PF17101.5 KIY64505.1 - 2.2e-07 30.5 0.1 4.7e-07 29.4 0.1 1.6 1 0 0 1 1 1 1 Stealth protein CR1, conserved region 1 Stealth_CR3 PF17102.5 KIY64505.1 - 6.2e-07 29.2 0.6 1.3e-06 28.2 0.2 1.9 2 0 0 2 2 2 1 Stealth protein CR3, conserved region 3 Stealth_CR4 PF17103.5 KIY64505.1 - 1.7e-05 24.6 0.0 3.8e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Stealth protein CR4, conserved region 4 5_3_exonuc_N PF02739.16 KIY64507.1 - 0.031 14.2 0.0 0.049 13.5 0.0 1.3 1 0 0 1 1 1 0 5'-3' exonuclease, N-terminal resolvase-like domain EthD PF07110.11 KIY64507.1 - 0.078 14.1 0.0 0.16 13.1 0.0 1.7 1 1 0 1 1 1 0 EthD domain SBDS_C PF09377.10 KIY64508.1 - 3.7e-35 120.4 1.2 7.7e-35 119.4 1.2 1.5 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.18 KIY64508.1 - 6e-33 112.8 3.6 9.7e-33 112.1 3.6 1.3 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein NdhM PF10664.9 KIY64508.1 - 0.0032 17.7 0.4 0.18 12.0 0.1 2.3 2 0 0 2 2 2 1 Cyanobacterial and plastid NDH-1 subunit M FMO-like PF00743.19 KIY64509.1 - 2e-24 85.9 0.0 1.6e-21 76.3 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KIY64509.1 - 2.5e-10 40.1 0.0 1e-08 34.8 0.0 2.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIY64509.1 - 5.4e-08 32.8 0.8 8.7e-06 25.5 0.3 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIY64509.1 - 3.2e-06 26.6 0.0 2.1e-05 23.9 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIY64509.1 - 1.1e-05 25.6 0.0 2.2e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KIY64509.1 - 1.1e-05 25.4 0.0 8.6e-05 22.6 0.0 2.4 2 1 0 2 2 2 1 FAD-NAD(P)-binding Amino_oxidase PF01593.24 KIY64509.1 - 0.0016 17.8 0.0 0.17 11.2 0.0 2.4 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 KIY64509.1 - 0.026 15.1 0.0 0.11 13.1 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KIY64509.1 - 0.039 13.1 0.1 6.8 5.7 0.0 2.5 2 1 1 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) Glu_dehyd_C PF16912.5 KIY64509.1 - 0.097 12.1 0.1 0.18 11.3 0.1 1.4 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus Glyco_hydro_18 PF00704.28 KIY64510.1 - 6.6e-65 219.9 0.3 7.6e-65 219.7 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 ANAPC4_WD40 PF12894.7 KIY64511.1 - 2.7e-12 46.8 0.0 0.61 10.4 0.0 5.6 3 2 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KIY64511.1 - 8.4e-08 32.8 6.7 4.6 8.3 0.0 6.6 6 1 0 6 6 6 3 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 KIY64511.1 - 0.051 12.6 0.0 4.9 6.1 0.0 2.2 2 0 0 2 2 2 0 Coatomer WD associated region IKI3 PF04762.12 KIY64511.1 - 0.063 11.3 0.0 4.7 5.1 0.0 2.9 3 1 1 4 4 4 0 IKI3 family FYVE PF01363.21 KIY64514.1 - 1.9e-17 63.2 5.4 4.2e-17 62.1 5.4 1.6 1 0 0 1 1 1 1 FYVE zinc finger zf-C3HC4_4 PF15227.6 KIY64514.1 - 0.049 13.8 2.5 1.2 9.4 0.1 3.1 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING IBR PF01485.21 KIY64514.1 - 0.17 12.1 5.9 0.22 11.7 2.1 2.5 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain zf-C3HC4_2 PF13923.6 KIY64514.1 - 1.3 8.9 7.8 3.1 7.7 3.0 2.6 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 KIY64514.1 - 4.6 7.5 13.2 2.9 8.1 1.2 2.7 3 0 0 3 3 3 0 B-box zinc finger SRP68 PF16969.5 KIY64516.1 - 3.2e-78 264.1 8.8 5e-78 263.5 8.8 1.3 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 GlgX_C PF18390.1 KIY64518.1 - 0.032 14.0 0.0 0.22 11.3 0.0 2.1 2 0 0 2 2 2 0 Glycogen debranching enzyme C-terminal domain CoA_trans PF01144.23 KIY64522.1 - 2e-102 341.2 4.7 2.5e-62 210.1 0.3 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 KIY64522.1 - 0.0012 18.7 0.1 0.0027 17.7 0.1 1.5 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain DUF3455 PF11937.8 KIY64523.1 - 5.5e-15 56.1 0.2 7.5e-15 55.7 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) MPP6 PF10175.9 KIY64525.1 - 3.2e-10 40.6 0.9 3.2e-10 40.6 0.9 1.8 2 0 0 2 2 2 1 M-phase phosphoprotein 6 FYVE PF01363.21 KIY64526.1 - 2.3e-17 62.9 0.9 3.8e-17 62.2 0.9 1.4 1 0 0 1 1 1 1 FYVE zinc finger Rbsn PF11464.8 KIY64526.1 - 7.1e-15 54.5 1.1 1.9e-14 53.1 1.1 1.8 1 0 0 1 1 1 1 Rabenosyn Rab binding domain FYVE_2 PF02318.16 KIY64526.1 - 0.17 12.1 0.2 0.46 10.7 0.2 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger zf-C2HC5 PF06221.13 KIY64526.1 - 0.2 11.6 9.1 0.096 12.7 6.8 1.6 2 0 0 2 2 2 0 Putative zinc finger motif, C2HC5-type IBR PF01485.21 KIY64526.1 - 0.84 9.9 4.3 1.7 9.0 4.3 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain CsbD PF05532.12 KIY64527.1 - 6.9e-16 57.9 15.3 7.7e-09 35.3 2.3 2.1 1 1 1 2 2 2 2 CsbD-like HSP9_HSP12 PF04119.12 KIY64527.1 - 0.051 14.0 0.4 0.096 13.1 0.3 1.6 1 1 0 1 1 1 0 Heat shock protein 9/12 CDC45 PF02724.14 KIY64528.1 - 9.6e-208 691.5 0.0 1.2e-207 691.2 0.0 1.0 1 0 0 1 1 1 1 CDC45-like protein IFT57 PF10498.9 KIY64528.1 - 0.12 11.4 3.3 0.19 10.7 3.3 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DUF4611 PF15387.6 KIY64528.1 - 2.1 8.6 7.0 5.6 7.3 7.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Arrestin_N PF00339.29 KIY64529.1 - 0.00046 20.3 0.0 0.0011 19.1 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain zf-Mss51 PF13824.6 KIY64530.1 - 2.5e-23 81.9 17.2 4.4e-22 77.9 17.5 2.3 1 1 1 2 2 2 2 Zinc-finger of mitochondrial splicing suppressor 51 Lar_restr_allev PF14354.6 KIY64530.1 - 2.7 8.4 8.0 5.5 7.4 8.0 1.5 1 0 0 1 1 1 0 Restriction alleviation protein Lar IGPD PF00475.18 KIY64531.1 - 8.4e-61 204.5 0.1 1.2e-60 204.1 0.1 1.2 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase MRP-S34 PF16053.5 KIY64534.1 - 4.7e-07 29.5 1.2 6.9e-07 29.0 1.2 1.2 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S34 Glu-tRNAGln PF02686.15 KIY64535.1 - 0.0027 17.9 0.0 0.0045 17.2 0.0 1.3 1 0 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit UAA PF08449.11 KIY64537.1 - 2.4e-78 263.4 13.8 2.7e-78 263.2 13.8 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 KIY64537.1 - 0.2 11.8 22.9 0.038 14.2 6.1 2.4 2 0 0 2 2 2 0 EamA-like transporter family Aldose_epim PF01263.20 KIY64538.1 - 5.6e-25 88.3 0.0 1.5e-24 86.9 0.0 1.6 1 1 0 1 1 1 1 Aldose 1-epimerase GxDLY PF14607.6 KIY64538.1 - 0.072 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 N-terminus of Esterase_SGNH_hydro-type Beta-lactamase PF00144.24 KIY64539.1 - 2.5e-39 135.4 0.6 3.9e-39 134.8 0.6 1.2 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 KIY64539.1 - 0.0021 18.5 0.2 0.0081 16.6 0.2 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF3471) bZIP_Maf PF03131.17 KIY64540.1 - 0.003 18.0 2.4 0.0059 17.1 2.4 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor KfrA_N PF11740.8 KIY64540.1 - 0.016 15.9 4.0 0.022 15.5 4.0 1.2 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term bZIP_1 PF00170.21 KIY64540.1 - 0.019 15.1 9.2 0.057 13.5 9.2 1.7 1 1 0 1 1 1 0 bZIP transcription factor bZIP_2 PF07716.15 KIY64540.1 - 0.067 13.3 9.1 0.11 12.5 9.1 1.4 1 0 0 1 1 1 0 Basic region leucine zipper BAH PF01426.18 KIY64542.1 - 0.00027 20.8 0.0 0.00039 20.3 0.0 1.3 1 0 0 1 1 1 1 BAH domain zf-RING-like PF08746.11 KIY64542.1 - 0.022 15.1 0.3 0.041 14.2 0.3 1.4 1 0 0 1 1 1 0 RING-like domain PHD PF00628.29 KIY64542.1 - 0.028 14.3 1.8 0.054 13.4 1.8 1.4 1 0 0 1 1 1 0 PHD-finger NAD_binding_1 PF00175.21 KIY64543.1 - 1.8e-05 25.3 0.0 3.7e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Putative_PNPOx PF01243.20 KIY64543.1 - 0.00055 20.1 0.0 0.027 14.6 0.0 2.8 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase FAD_binding_6 PF00970.24 KIY64543.1 - 0.0033 17.7 0.0 0.53 10.7 0.0 2.3 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KIY64543.1 - 0.014 15.5 0.0 0.26 11.4 0.0 2.3 2 0 0 2 2 2 0 Ferric reductase NAD binding domain ADH_zinc_N PF00107.26 KIY64544.1 - 4.5e-30 104.3 0.2 7.6e-30 103.5 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIY64544.1 - 3.1e-28 97.8 3.0 5.6e-28 97.0 3.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KIY64544.1 - 0.00018 22.6 0.1 0.00038 21.5 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase zf-C3HC4_3 PF13920.6 KIY64545.1 - 8.4e-11 41.6 5.5 7.8e-09 35.3 1.5 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KIY64545.1 - 0.001 18.9 4.4 0.001 18.9 4.4 2.2 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KIY64545.1 - 0.0013 19.0 6.3 0.0029 17.9 1.6 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 KIY64545.1 - 0.0057 16.6 2.7 0.05 13.6 0.7 2.3 2 0 0 2 2 2 1 zinc-RING finger domain Troponin-I_N PF11636.8 KIY64545.1 - 0.068 13.1 5.6 0.26 11.3 1.5 2.9 2 0 0 2 2 2 0 Troponin I residues 1-32 zf-C3HC4_2 PF13923.6 KIY64545.1 - 0.47 10.3 5.2 0.27 11.1 1.8 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KIY64545.1 - 8.4 6.5 9.9 9.7 6.3 1.2 2.8 3 0 0 3 3 3 0 RING-type zinc-finger ADH_zinc_N PF00107.26 KIY64546.1 - 9.1e-30 103.3 0.6 1.5e-29 102.6 0.6 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIY64546.1 - 1.6e-27 95.5 1.9 2.7e-27 94.8 1.9 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KIY64546.1 - 0.00034 21.7 0.2 0.00058 20.9 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Fer4_4 PF12800.7 KIY64546.1 - 7.9 7.3 7.5 3.6 8.3 2.2 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain PIP5K PF01504.18 KIY64547.1 - 7.6e-104 346.8 0.4 7.6e-104 346.8 0.4 1.6 2 0 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase Cwf_Cwc_15 PF04889.12 KIY64547.1 - 1.1 8.9 7.1 0.066 12.9 0.7 1.9 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Fungal_trans PF04082.18 KIY64549.1 - 3.8e-14 52.4 0.0 7.6e-14 51.4 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY64549.1 - 3.1e-05 24.0 12.6 7e-05 22.9 12.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_zinc_N PF00107.26 KIY64550.1 - 9e-30 103.3 0.6 1.5e-29 102.6 0.6 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIY64550.1 - 9.2e-28 96.3 1.8 1.6e-27 95.6 1.8 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KIY64550.1 - 0.00034 21.7 0.2 0.00058 20.9 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Fer4_4 PF12800.7 KIY64550.1 - 7.9 7.3 7.5 3.6 8.3 2.2 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Cnd1 PF12717.7 KIY64551.1 - 2.5e-48 164.2 6.7 1.6e-45 155.1 0.0 4.2 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.7 KIY64551.1 - 1.3e-25 90.1 1.2 3.5e-25 88.8 0.0 2.3 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT PF02985.22 KIY64551.1 - 0.0029 17.7 2.1 3 8.4 0.1 4.9 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.6 KIY64551.1 - 0.017 15.6 1.8 69 4.1 0.0 5.0 5 0 0 5 5 5 0 HEAT-like repeat Crp PF00325.20 KIY64551.1 - 0.026 14.2 0.1 0.091 12.4 0.1 2.0 1 0 0 1 1 1 0 Bacterial regulatory proteins, crp family RTP1_C1 PF10363.9 KIY64551.1 - 0.067 13.4 1.7 2.7 8.2 0.1 3.5 3 1 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 Xpo1 PF08389.12 KIY64551.1 - 0.28 11.2 2.3 0.84 9.7 0.1 2.8 2 1 1 3 3 3 0 Exportin 1-like protein DPBB_1 PF03330.18 KIY64552.1 - 2.6e-07 30.8 0.1 4.2e-07 30.1 0.1 1.4 1 1 0 1 1 1 1 Lytic transglycolase Ank_4 PF13637.6 KIY64553.1 - 1.1e-17 64.2 0.2 1.9e-07 31.5 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KIY64553.1 - 2.7e-14 53.0 0.1 2.5e-12 46.7 0.1 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KIY64553.1 - 2e-10 41.1 0.0 5.3e-10 39.8 0.0 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KIY64553.1 - 2.3e-10 39.8 0.1 9.9e-06 25.5 0.1 3.9 4 1 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 KIY64553.1 - 1.4e-09 37.9 0.1 0.00037 20.8 0.1 3.3 3 0 0 3 3 3 3 Ankyrin repeat AbiEi_4 PF13338.6 KIY64553.1 - 0.055 13.6 0.0 0.23 11.6 0.0 1.9 2 0 0 2 2 2 0 Transcriptional regulator, AbiEi antitoxin Mem_trans PF03547.18 KIY64554.1 - 1.7e-38 132.1 6.0 4.5e-38 130.6 6.0 1.7 1 1 0 1 1 1 1 Membrane transport protein adh_short PF00106.25 KIY64555.1 - 1.6e-21 76.7 0.0 2.7e-15 56.4 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KIY64555.1 - 2e-11 43.9 0.0 3.6e-07 30.0 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIY64555.1 - 1.1e-05 25.4 0.1 1.6e-05 24.9 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KIY64555.1 - 0.003 17.1 0.0 0.0044 16.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DTHCT PF08070.11 KIY64556.1 - 0.043 14.6 7.6 0.091 13.5 7.6 1.5 1 0 0 1 1 1 0 DTHCT (NUC029) region DUF3874 PF12990.7 KIY64556.1 - 0.096 13.0 0.0 0.17 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknonw function from B. Theta Gene description (DUF3874) NfI_DNAbd_pre-N PF10524.9 KIY64556.1 - 0.19 11.6 0.0 0.5 10.3 0.0 1.6 1 0 0 1 1 1 0 Nuclear factor I protein pre-N-terminus Rpn9_C PF18261.1 KIY64556.1 - 0.33 10.6 0.2 0.33 10.6 0.2 1.7 2 0 0 2 2 2 0 Rpn9 C-terminal helix Fer4_6 PF12837.7 KIY64558.1 - 0.12 12.5 0.4 0.12 12.5 0.4 2.4 3 0 0 3 3 3 0 4Fe-4S binding domain Asp PF00026.23 KIY64559.1 - 1.6e-60 205.2 0.0 1.9e-60 205.0 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIY64559.1 - 7.3e-10 39.4 0.4 2.9e-08 34.1 0.4 2.9 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KIY64559.1 - 0.0075 16.9 0.5 0.96 10.1 0.0 3.1 2 1 0 2 2 2 1 Aspartyl protease RF-1 PF00472.20 KIY64561.1 - 3.8e-21 75.2 2.1 5.6e-21 74.6 2.1 1.2 1 0 0 1 1 1 1 RF-1 domain Ras PF00071.22 KIY64562.1 - 7.8e-59 197.9 0.3 9.1e-59 197.7 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIY64562.1 - 8.6e-21 74.4 0.0 1.5e-20 73.6 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIY64562.1 - 1.2e-09 37.9 0.0 1.4e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KIY64562.1 - 1.1e-05 25.1 0.1 2.7e-05 23.8 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KIY64562.1 - 4.3e-05 23.5 0.0 0.1 12.5 0.0 2.3 2 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KIY64562.1 - 0.0014 18.7 0.0 0.0025 17.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 KIY64562.1 - 0.0066 15.6 0.0 0.26 10.4 0.1 2.0 2 0 0 2 2 2 1 G-protein alpha subunit FeoB_N PF02421.18 KIY64562.1 - 0.011 15.3 0.1 0.026 14.0 0.1 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B ATP_bind_1 PF03029.17 KIY64562.1 - 0.09 12.5 2.9 0.33 10.7 0.1 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein CIA30 PF08547.12 KIY64563.1 - 2.9e-26 92.4 0.0 3.7e-26 92.1 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) Cys_Met_Meta_PP PF01053.20 KIY64564.1 - 3.7e-127 424.0 0.0 4.7e-127 423.7 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme GHMP_kinases_N PF00288.26 KIY64564.1 - 7.5e-17 61.3 0.1 2.7e-16 59.5 0.1 2.1 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KIY64564.1 - 1.3e-05 25.4 0.0 3.9e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal Aminotran_1_2 PF00155.21 KIY64564.1 - 0.002 17.4 0.0 0.0033 16.6 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KIY64564.1 - 0.0073 15.7 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Met_gamma_lyase PF06838.11 KIY64564.1 - 0.013 14.1 0.0 0.069 11.7 0.0 1.9 1 1 0 1 1 1 0 Methionine gamma-lyase GalKase_gal_bdg PF10509.9 KIY64564.1 - 0.039 13.5 0.0 0.091 12.3 0.0 1.6 1 0 0 1 1 1 0 Galactokinase galactose-binding signature Beta_elim_lyase PF01212.21 KIY64564.1 - 0.092 12.0 0.1 0.18 11.0 0.1 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase RNA_pol_Rpb5_C PF01191.19 KIY64565.1 - 1.6e-31 108.0 0.1 3.6e-31 106.9 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 KIY64565.1 - 2.5e-26 92.0 0.1 4.1e-26 91.4 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.12 KIY64565.1 - 0.0048 16.9 0.0 0.015 15.3 0.0 1.8 3 0 0 3 3 3 1 Restriction endonuclease R3H PF01424.22 KIY64565.1 - 0.067 13.2 0.1 0.67 10.0 0.0 2.5 3 0 0 3 3 3 0 R3H domain WD40 PF00400.32 KIY64566.1 - 1.5e-17 63.6 0.1 0.0063 17.3 0.0 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY64566.1 - 1.2e-09 38.3 0.0 0.41 11.0 0.0 5.1 2 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIY64566.1 - 0.099 12.6 0.8 4.8 7.2 0.0 2.8 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat DEAD PF00270.29 KIY64567.1 - 2.3e-38 131.7 0.0 5.3e-38 130.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIY64567.1 - 1.3e-23 83.4 0.1 3.3e-22 78.9 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIY64567.1 - 1e-08 35.4 0.1 6.1e-08 32.9 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CDC27 PF09507.10 KIY64567.1 - 0.014 14.9 13.0 0.019 14.4 13.0 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 AAA_22 PF13401.6 KIY64567.1 - 0.082 13.2 1.0 3.7 7.8 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.6 KIY64567.1 - 0.14 12.4 0.0 0.3 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain MEA1 PF06910.11 KIY64567.1 - 2.2 8.9 9.2 1.1 9.9 6.9 1.7 2 0 0 2 2 2 0 Male enhanced antigen 1 (MEA1) Presenilin PF01080.17 KIY64567.1 - 6.1 5.5 6.7 8.3 5.1 6.7 1.2 1 0 0 1 1 1 0 Presenilin BTB PF00651.31 KIY64568.1 - 5e-18 65.4 0.0 1.1e-07 32.1 0.0 3.1 2 1 1 3 3 3 2 BTB/POZ domain RCC1 PF00415.18 KIY64568.1 - 4.4e-17 62.5 7.7 0.0018 18.9 0.0 5.5 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat Ank_4 PF13637.6 KIY64568.1 - 1.7e-10 41.2 0.5 1.6e-09 38.1 0.1 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KIY64568.1 - 3.9e-09 37.0 0.0 1.5e-08 35.1 0.0 2.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) RCC1_2 PF13540.6 KIY64568.1 - 7.4e-09 35.2 0.1 7.4e-09 35.2 0.1 4.9 6 0 0 6 6 6 1 Regulator of chromosome condensation (RCC1) repeat Ank_3 PF13606.6 KIY64568.1 - 2.9e-08 33.3 1.2 0.0033 17.8 0.1 3.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KIY64568.1 - 8e-07 29.2 1.6 0.0089 16.3 0.2 3.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KIY64568.1 - 6e-05 23.3 2.4 0.0093 16.4 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat Activator_LAG-3 PF11498.8 KIY64568.1 - 0.017 14.1 0.3 0.032 13.2 0.3 1.4 1 0 0 1 1 1 0 Transcriptional activator LAG-3 EKLF_TAD1 PF16832.5 KIY64568.1 - 1.4 8.8 5.3 4.4 7.3 5.3 1.8 1 0 0 1 1 1 0 Erythroid krueppel-like transcription factor, transactivation 1 ADH_N PF08240.12 KIY64569.1 - 3.6e-26 91.2 1.5 3.6e-26 91.2 1.5 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KIY64569.1 - 1.9e-19 69.9 0.4 2.3e-18 66.4 0.1 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KIY64569.1 - 3.4e-05 24.9 0.1 7.5e-05 23.8 0.1 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.18 KIY64569.1 - 0.1 12.8 0.0 0.24 11.7 0.0 1.6 1 1 0 1 1 1 0 TrkA-N domain SET PF00856.28 KIY64570.1 - 3.8e-11 43.7 0.2 1.6e-10 41.6 0.2 1.9 1 1 0 1 1 1 1 SET domain SopA_C PF13979.6 KIY64570.1 - 0.093 12.5 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 SopA-like catalytic domain UDG PF03167.19 KIY64572.1 - 2.3e-21 76.4 0.0 6.2e-21 75.0 0.0 1.7 1 1 0 1 1 1 1 Uracil DNA glycosylase superfamily DUF702 PF05142.12 KIY64572.1 - 0.21 12.1 2.5 0.34 11.4 2.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF702) DUF3275 PF11679.8 KIY64572.1 - 0.26 11.2 2.2 0.43 10.5 2.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) ORC6 PF05460.13 KIY64572.1 - 0.35 10.1 7.7 0.5 9.6 7.7 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) bZIP_1 PF00170.21 KIY64573.1 - 3.1e-05 24.0 4.1 4.8e-05 23.4 4.0 1.4 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KIY64573.1 - 0.00044 20.3 0.5 0.00044 20.3 0.5 1.6 2 0 0 2 2 2 1 Basic region leucine zipper Shugoshin_N PF07558.11 KIY64573.1 - 0.0028 17.5 0.0 0.0043 16.9 0.0 1.3 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region TSC22 PF01166.18 KIY64573.1 - 0.0033 17.7 0.0 0.0047 17.2 0.0 1.2 1 0 0 1 1 1 1 TSC-22/dip/bun family Nnf1 PF03980.14 KIY64573.1 - 0.056 13.8 0.1 0.062 13.7 0.1 1.1 1 0 0 1 1 1 0 Nnf1 HAP1_N PF04849.13 KIY64573.1 - 0.095 11.9 0.1 0.1 11.8 0.1 1.0 1 0 0 1 1 1 0 HAP1 N-terminal conserved region ERCC3_RAD25_C PF16203.5 KIY64574.1 - 2.6e-123 410.1 0.0 5.5e-123 409.0 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 KIY64574.1 - 9.5e-38 129.2 0.0 2.2e-37 128.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIY64574.1 - 2.1e-16 60.4 0.0 3.7e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KIY64574.1 - 7.6e-11 42.3 0.1 2e-10 41.0 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 KIY64574.1 - 3.2e-09 36.0 0.0 4.3e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain SBP_bac_6 PF13343.6 KIY64574.1 - 0.11 11.9 0.0 0.26 10.7 0.0 1.6 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein SF1-HH PF16275.5 KIY64575.1 - 5.7e-39 133.0 2.2 1.1e-38 132.1 2.2 1.5 1 0 0 1 1 1 1 Splicing factor 1 helix-hairpin domain zf-CCHC PF00098.23 KIY64575.1 - 1.1e-11 44.2 8.9 1.4e-05 24.9 0.3 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.6 KIY64575.1 - 2.6e-07 30.5 4.2 0.0002 21.2 1.3 2.5 1 1 1 2 2 2 2 Zinc knuckle KH_1 PF00013.29 KIY64575.1 - 1.2e-05 25.0 0.0 2.2e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 KH domain zf-CCHC_4 PF14392.6 KIY64575.1 - 0.0056 16.4 7.1 0.4 10.4 0.6 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.6 KIY64575.1 - 0.014 15.2 8.3 0.26 11.2 0.6 2.7 1 1 1 2 2 2 0 Zinc knuckle CCDC-167 PF15188.6 KIY64575.1 - 0.059 13.7 1.6 1.9 8.9 0.2 2.4 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Prim_Zn_Ribbon PF08273.12 KIY64575.1 - 0.11 12.8 3.2 0.24 11.7 3.2 1.5 1 0 0 1 1 1 0 Zinc-binding domain of primase-helicase DnaJ_CXXCXGXG PF00684.19 KIY64575.1 - 0.3 11.5 4.6 0.63 10.4 4.6 1.5 1 0 0 1 1 1 0 DnaJ central domain zf-CCHC_2 PF13696.6 KIY64575.1 - 5.4 6.9 10.2 0.4 10.5 0.9 2.4 2 0 0 2 2 2 0 Zinc knuckle Glyco_hydro_76 PF03663.14 KIY64576.1 - 3.9e-28 99.0 14.8 5.8e-25 88.6 0.5 2.0 2 0 0 2 2 2 2 Glycosyl hydrolase family 76 Imm35 PF15567.6 KIY64576.1 - 0.0085 16.2 0.0 0.028 14.6 0.0 1.9 2 0 0 2 2 2 1 Immunity protein 35 PP2C PF00481.21 KIY64577.1 - 1.1e-84 284.1 0.0 1.1e-84 284.1 0.0 1.5 2 0 0 2 2 2 1 Protein phosphatase 2C PP2C_2 PF13672.6 KIY64577.1 - 0.00025 20.7 0.0 0.00067 19.3 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C Amidase PF01425.21 KIY64579.1 - 1.4e-102 344.0 0.0 1.9e-102 343.6 0.0 1.2 1 0 0 1 1 1 1 Amidase WD40 PF00400.32 KIY64580.1 - 0.25 12.3 5.2 4.3 8.4 0.1 3.8 4 1 0 4 4 4 0 WD domain, G-beta repeat Self-incomp_S1 PF05938.11 KIY64581.1 - 0.00089 19.8 0.0 9.6 6.8 0.0 4.1 2 1 3 5 5 5 2 Plant self-incompatibility protein S1 Trns_repr_metal PF02583.17 KIY64581.1 - 0.06 13.7 13.0 1.9 8.9 0.2 5.1 1 1 2 4 4 4 0 Metal-sensitive transcriptional repressor Fungal_trans PF04082.18 KIY64582.1 - 5.6e-06 25.6 0.5 1.2e-05 24.5 0.5 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY64582.1 - 0.15 12.2 3.9 0.29 11.3 3.9 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1690 PF07956.11 KIY64583.1 - 1.5e-36 125.9 2.2 1.9e-36 125.6 2.2 1.1 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) Rootletin PF15035.6 KIY64583.1 - 0.0064 16.5 5.7 0.025 14.6 5.8 1.7 1 1 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion Metal_resist PF13801.6 KIY64583.1 - 0.029 14.5 2.0 0.044 14.0 2.0 1.3 1 0 0 1 1 1 0 Heavy-metal resistance STAT_int PF02865.17 KIY64583.1 - 0.052 14.0 0.5 0.075 13.5 0.5 1.4 1 0 0 1 1 1 0 STAT protein, protein interaction domain Atg14 PF10186.9 KIY64583.1 - 0.22 10.6 5.6 0.074 12.1 2.6 1.6 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Toxin_25 PF08095.11 KIY64583.1 - 1.6 8.8 5.4 6.9 6.7 5.4 2.0 1 1 0 1 1 1 0 Hefutoxin family T2SSM PF04612.12 KIY64584.1 - 0.00015 21.8 0.2 0.00028 21.0 0.2 1.3 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein M DUF4381 PF14316.6 KIY64584.1 - 0.026 14.8 0.2 0.098 12.9 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) EphA2_TM PF14575.6 KIY64584.1 - 0.12 13.2 0.0 0.32 11.9 0.0 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain PRIMA1 PF16101.5 KIY64584.1 - 0.19 11.8 4.1 0.6 10.2 1.0 2.4 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 LapA_dom PF06305.11 KIY64584.1 - 0.25 11.2 0.2 0.57 10.0 0.2 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Pkinase PF00069.25 KIY64585.1 - 2.7e-12 46.6 0.0 3.1e-12 46.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY64585.1 - 2e-06 27.3 0.0 2.5e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY64585.1 - 0.00074 18.9 0.0 0.0013 18.1 0.0 1.3 1 1 0 1 1 1 1 Kinase-like LIM PF00412.22 KIY64586.1 - 2.3e-28 98.2 21.7 1.1e-12 48.0 3.3 3.6 3 1 0 3 3 3 3 LIM domain DUF2321 PF10083.9 KIY64586.1 - 0.055 13.1 3.5 0.036 13.7 1.1 1.8 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) Myosin_head PF00063.21 KIY64587.1 - 3.1e-259 861.8 0.1 2.8e-258 858.6 0.0 2.1 2 0 0 2 2 2 1 Myosin head (motor domain) DIL PF01843.19 KIY64587.1 - 1.8e-26 92.4 1.4 1.8e-26 92.4 1.4 3.1 3 0 0 3 3 3 1 DIL domain IQ PF00612.27 KIY64587.1 - 1.5e-10 39.9 39.7 0.01 15.5 1.6 7.0 6 0 0 6 6 6 5 IQ calmodulin-binding motif Myosin_N PF02736.19 KIY64587.1 - 0.032 14.1 0.3 0.067 13.0 0.3 1.6 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain AAA_22 PF13401.6 KIY64587.1 - 0.035 14.4 0.0 0.035 14.4 0.0 2.6 2 1 0 2 2 2 0 AAA domain NACHT PF05729.12 KIY64587.1 - 0.041 13.8 0.0 0.12 12.3 0.0 1.8 1 0 0 1 1 1 0 NACHT domain Lebercilin PF15619.6 KIY64587.1 - 0.057 13.1 31.6 0.17 11.5 31.6 1.9 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease MutS_III PF05192.18 KIY64587.1 - 0.097 12.9 2.9 0.33 11.1 1.3 2.7 2 0 0 2 2 2 0 MutS domain III AAA_16 PF13191.6 KIY64587.1 - 0.94 9.8 0.0 0.94 9.8 0.0 3.4 2 1 1 3 3 3 0 AAA ATPase domain TPR_MLP1_2 PF07926.12 KIY64587.1 - 6.6 6.8 34.1 0.42 10.7 13.6 2.8 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF1664 PF07889.12 KIY64587.1 - 7.1 6.7 13.9 3.4 7.7 1.5 3.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) ING PF12998.7 KIY64587.1 - 8.7 7.0 11.9 29 5.3 11.9 1.9 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding SNCAIP_SNCA_bd PF16700.5 KIY64587.1 - 9.1 6.1 12.8 0.29 10.9 3.7 3.0 3 0 0 3 3 3 0 Synphilin-1 alpha-Synuclein-binding domain Actin PF00022.19 KIY64588.1 - 2.6e-43 148.2 0.0 1.4e-20 73.3 0.0 2.2 2 0 0 2 2 2 2 Actin DUF1539 PF07560.11 KIY64588.1 - 0.29 11.2 2.6 0.92 9.6 0.8 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1539) DUF2340 PF10209.9 KIY64589.1 - 2.8e-51 173.0 0.6 3.3e-51 172.8 0.6 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) Blt1 PF12754.7 KIY64589.1 - 0.022 15.1 0.0 0.026 14.8 0.0 1.1 1 0 0 1 1 1 0 Blt1 N-terminal domain Transp_cyt_pur PF02133.15 KIY64590.1 - 3.8e-31 108.3 32.0 6.7e-31 107.5 32.0 1.4 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Glyco_hydro_3_C PF01915.22 KIY64591.1 - 2.3e-61 207.3 0.0 4e-61 206.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KIY64591.1 - 3.4e-44 151.5 0.0 5.9e-44 150.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KIY64591.1 - 5e-19 68.2 0.0 8.8e-19 67.4 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 KIY64591.1 - 3.1e-09 36.8 0.0 6.3e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 PA14 domain zf-MYND PF01753.18 KIY64592.1 - 1.8e-08 34.3 11.5 3.5e-08 33.4 11.5 1.5 1 0 0 1 1 1 1 MYND finger Lenti_VIF_2 PF07401.12 KIY64592.1 - 0.069 12.5 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Bovine Lentivirus VIF protein Pkinase PF00069.25 KIY64594.1 - 2.2e-38 132.2 0.0 3e-38 131.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY64594.1 - 7.4e-38 130.3 0.0 9.7e-38 129.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIY64594.1 - 0.00064 18.6 0.0 0.0011 17.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Spo7_2_N PF15407.6 KIY64601.1 - 0.18 11.4 0.0 0.36 10.5 0.0 1.4 1 0 0 1 1 1 0 Sporulation protein family 7 AAA_30 PF13604.6 KIY64603.1 - 0.068 12.9 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain STE3 PF02076.15 KIY64604.1 - 1.8e-108 362.1 16.9 2.3e-108 361.8 16.9 1.1 1 0 0 1 1 1 1 Pheromone A receptor Mid2 PF04478.12 KIY64604.1 - 0.16 11.8 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor S6OS1 PF15676.5 KIY64604.1 - 0.29 9.6 0.0 0.42 9.0 0.0 1.1 1 0 0 1 1 1 0 Six6 opposite strand transcript 1 family Lipase_GDSL_2 PF13472.6 KIY64607.1 - 1.2e-12 48.6 4.1 1.4e-12 48.4 4.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KIY64607.1 - 1.8e-08 34.6 0.3 2.2e-08 34.3 0.3 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase ALGX PF16822.5 KIY64607.1 - 0.0016 18.2 0.7 0.013 15.2 0.2 2.1 2 0 0 2 2 2 1 SGNH hydrolase-like domain, acetyltransferase AlgX DUF1330 PF07045.11 KIY64607.1 - 0.058 13.7 0.1 7.9 6.9 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1330) DUF2229 PF09989.9 KIY64607.1 - 0.16 11.6 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) EzrA PF06160.12 KIY64608.1 - 0.00062 18.1 0.0 0.00091 17.5 0.0 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA KLRAQ PF10205.9 KIY64608.1 - 0.0013 18.9 3.4 0.0033 17.6 3.4 1.7 1 0 0 1 1 1 1 Predicted coiled-coil domain-containing protein Jnk-SapK_ap_N PF09744.9 KIY64608.1 - 0.0016 18.7 2.3 0.0035 17.6 2.3 1.5 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 DUF4407 PF14362.6 KIY64608.1 - 0.0018 17.7 0.2 0.0037 16.7 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) TolA_bind_tri PF16331.5 KIY64608.1 - 0.0025 17.8 1.5 0.0025 17.8 1.5 3.0 4 1 1 5 5 3 1 TolA binding protein trimerisation Laminin_II PF06009.12 KIY64608.1 - 0.0028 17.7 3.0 0.0053 16.8 3.0 1.4 1 0 0 1 1 1 1 Laminin Domain II Ribosomal_S30AE PF02482.19 KIY64608.1 - 0.0031 18.3 0.7 0.0031 18.3 0.7 1.8 2 0 0 2 2 1 1 Sigma 54 modulation protein / S30EA ribosomal protein HOOK PF05622.12 KIY64608.1 - 0.0034 15.6 1.1 0.0048 15.1 1.1 1.1 1 0 0 1 1 1 1 HOOK protein Fib_alpha PF08702.10 KIY64608.1 - 0.004 17.4 0.6 0.0075 16.5 0.6 1.4 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family KASH_CCD PF14662.6 KIY64608.1 - 0.0049 16.7 2.1 0.0077 16.1 2.1 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH AAA_13 PF13166.6 KIY64608.1 - 0.013 14.2 0.1 0.019 13.7 0.1 1.1 1 0 0 1 1 1 0 AAA domain TPR_MLP1_2 PF07926.12 KIY64608.1 - 0.043 13.9 5.5 0.081 13.0 5.5 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Mod_r PF07200.13 KIY64608.1 - 0.056 13.6 1.0 0.12 12.5 1.0 1.5 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein DUF2951 PF11166.8 KIY64608.1 - 0.11 12.7 2.4 0.36 11.1 2.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2951) DUF1664 PF07889.12 KIY64608.1 - 0.11 12.5 3.4 0.23 11.5 3.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Rhamno_transf PF11316.8 KIY64608.1 - 0.12 11.7 1.2 0.2 11.0 1.2 1.2 1 0 0 1 1 1 0 Putative rhamnosyl transferase UPF0242 PF06785.11 KIY64608.1 - 0.18 11.9 5.3 0.23 11.5 3.9 1.8 2 1 0 2 2 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4164 PF13747.6 KIY64608.1 - 0.2 12.0 6.3 0.29 11.4 3.1 2.4 3 0 0 3 3 2 0 Domain of unknown function (DUF4164) NPV_P10 PF05531.12 KIY64608.1 - 0.27 11.7 2.8 11 6.6 2.3 2.7 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF2508 PF10704.9 KIY64608.1 - 0.33 11.2 2.2 0.69 10.1 2.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2508) FliJ PF02050.16 KIY64608.1 - 0.82 9.9 8.3 4.9 7.4 8.3 2.1 1 1 1 2 2 2 0 Flagellar FliJ protein DUF16 PF01519.16 KIY64608.1 - 0.83 10.2 3.6 7.6 7.1 2.2 2.3 1 1 1 2 2 2 0 Protein of unknown function DUF16 TMPIT PF07851.13 KIY64608.1 - 0.94 8.7 2.0 1.2 8.3 0.4 1.9 2 0 0 2 2 2 0 TMPIT-like protein XhlA PF10779.9 KIY64608.1 - 2 8.7 8.5 0.17 12.1 1.6 2.6 2 1 1 3 3 3 0 Haemolysin XhlA Med9 PF07544.13 KIY64608.1 - 2.2 8.4 5.8 0.27 11.4 1.3 1.8 2 0 0 2 2 1 0 RNA polymerase II transcription mediator complex subunit 9 Snapin_Pallidin PF14712.6 KIY64608.1 - 3 8.3 6.5 6.1 7.3 4.6 2.3 1 1 0 2 2 2 0 Snapin/Pallidin SlyX PF04102.12 KIY64608.1 - 5.1 7.8 8.9 25 5.6 1.7 3.8 1 1 2 3 3 3 0 SlyX DivIC PF04977.15 KIY64608.1 - 7.7 6.4 7.7 4.5 7.1 2.6 2.6 2 1 1 3 3 2 0 Septum formation initiator DUF4061 PF13270.6 KIY64609.1 - 0.5 10.7 2.9 27 5.2 1.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4061) YL1 PF05764.13 KIY64609.1 - 2.8 8.0 29.6 4.5 7.3 29.6 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Vfa1 PF08432.10 KIY64609.1 - 8.8 6.6 15.2 7.2 6.9 12.1 2.0 1 1 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 TFIIF_alpha PF05793.12 KIY64610.1 - 0.0079 14.8 14.5 0.011 14.3 14.5 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) eIF3_subunit PF08597.10 KIY64610.1 - 0.1 12.5 11.5 0.15 12.0 11.5 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit zf-C2H2_12 PF18658.1 KIY64610.1 - 0.12 11.9 0.0 0.48 10.0 0.0 2.0 2 0 0 2 2 2 0 Zinc-finger C2H2-type STE3 PF02076.15 KIY64611.1 - 4.1e-98 328.1 15.1 4.9e-98 327.9 15.1 1.0 1 0 0 1 1 1 1 Pheromone A receptor DUF973 PF06157.11 KIY64611.1 - 0.0015 17.6 0.1 0.0024 17.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF973) Neuralized PF07177.12 KIY64612.1 - 0.14 12.1 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 Neuralized FtsL PF04999.13 KIY64615.1 - 0.025 14.6 0.3 2.8 8.0 0.1 2.3 2 0 0 2 2 2 0 Cell division protein FtsL RCDG1 PF15725.5 KIY64617.1 - 0.0098 16.3 2.4 0.014 15.8 2.4 1.4 1 0 0 1 1 1 1 Renal cancer differentiation gene 1 protein PrpF PF04303.13 KIY64623.1 - 1.1e-68 232.0 2.0 1.9e-68 231.1 2.0 1.4 1 1 0 1 1 1 1 PrpF protein Oxidored_FMN PF00724.20 KIY64624.1 - 1.7e-104 349.8 0.0 1.9e-104 349.6 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family CS PF04969.16 KIY64625.1 - 2.1e-05 25.5 0.0 3.6e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 CS domain PLDc_3 PF13918.6 KIY64625.1 - 0.00041 20.1 0.1 0.00055 19.6 0.1 1.1 1 0 0 1 1 1 1 PLD-like domain AAA_assoc_C PF09821.9 KIY64625.1 - 0.13 12.8 0.0 0.18 12.3 0.0 1.2 1 0 0 1 1 1 0 C-terminal AAA-associated domain Forkhead_N PF08430.12 KIY64625.1 - 0.16 12.6 7.5 0.22 12.1 7.5 1.2 1 0 0 1 1 1 0 Forkhead N-terminal region H2TH PF06831.14 KIY64625.1 - 0.2 11.7 0.2 0.94 9.5 0.0 2.1 3 0 0 3 3 3 0 Formamidopyrimidine-DNA glycosylase H2TH domain BC10 PF06726.12 KIY64626.1 - 5.1e-08 33.0 10.8 7.5e-08 32.5 10.8 1.2 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 SF3A2 PF16835.5 KIY64627.1 - 1.2e-36 124.9 0.2 1.8e-36 124.3 0.2 1.3 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 KIY64627.1 - 2e-06 28.0 0.7 2e-06 28.0 0.7 1.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type PRP4 PF08799.11 KIY64627.1 - 0.014 14.9 0.9 0.026 14.1 0.9 1.4 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like CactinC_cactus PF09732.9 KIY64627.1 - 0.023 14.7 0.1 0.037 14.0 0.1 1.4 1 0 0 1 1 1 0 Cactus-binding C-terminus of cactin protein DUF3995 PF13160.6 KIY64628.1 - 0.032 14.6 4.0 0.044 14.1 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3995) p450 PF00067.22 KIY64631.1 - 2.2e-77 260.8 0.0 2.5e-77 260.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.7 KIY64632.1 - 2.4e-09 37.0 0.2 2.9e-08 33.5 0.0 2.7 2 1 0 2 2 2 1 F-box-like F-box PF00646.33 KIY64632.1 - 0.045 13.6 0.2 3.8 7.5 0.0 2.9 2 0 0 2 2 2 0 F-box domain PEP-utilisers_N PF05524.13 KIY64632.1 - 0.16 12.1 0.6 0.3 11.3 0.6 1.3 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal F-box-like PF12937.7 KIY64633.1 - 1.2e-08 34.6 0.2 7.3e-08 32.2 0.1 2.4 2 1 0 2 2 2 1 F-box-like TPR_MLP1_2 PF07926.12 KIY64633.1 - 0.0047 17.0 3.4 0.0074 16.3 3.4 1.2 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein DUF2353 PF09789.9 KIY64633.1 - 0.0061 16.0 1.2 0.0088 15.4 1.2 1.1 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) GrpE PF01025.19 KIY64633.1 - 0.015 15.0 2.1 0.025 14.2 2.1 1.3 1 0 0 1 1 1 0 GrpE ADIP PF11559.8 KIY64633.1 - 0.16 12.0 4.3 0.27 11.3 4.3 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding F-box PF00646.33 KIY64633.1 - 0.19 11.7 1.8 2.8 7.9 0.2 3.2 3 0 0 3 3 3 0 F-box domain PHM7_cyt PF14703.6 KIY64633.1 - 0.27 11.4 1.3 0.73 10.0 1.3 1.5 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter TMF_DNA_bd PF12329.8 KIY64633.1 - 1.2 9.2 4.4 2.1 8.4 4.4 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding ATP-synt_E PF05680.12 KIY64634.1 - 0.39 11.1 2.1 0.98 9.8 2.1 1.6 1 0 0 1 1 1 0 ATP synthase E chain Cu-oxidase_2 PF07731.14 KIY64641.1 - 3.2e-23 82.0 1.6 1.7e-16 60.2 0.0 3.0 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KIY64641.1 - 5.6e-22 78.0 0.0 1.8e-21 76.3 0.0 1.9 1 1 0 1 1 1 1 Multicopper oxidase Cu-oxidase PF00394.22 KIY64641.1 - 9.6e-10 38.8 0.0 1.1e-08 35.4 0.0 2.4 2 0 0 2 2 2 1 Multicopper oxidase F-box-like PF12937.7 KIY64642.1 - 0.00034 20.4 0.0 0.00092 19.1 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY64642.1 - 0.0028 17.5 0.0 0.006 16.4 0.0 1.6 1 0 0 1 1 1 1 F-box domain HicA_toxin PF07927.12 KIY64643.1 - 2.1e-06 27.6 0.0 6.2e-06 26.2 0.0 1.8 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, Zn_clus PF00172.18 KIY64644.1 - 5.2e-07 29.7 8.9 5.2e-07 29.7 8.9 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugarporin_N PF11471.8 KIY64644.1 - 0.54 10.2 2.6 0.97 9.4 0.8 2.1 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension JAB PF01398.21 KIY64646.1 - 2.5e-16 59.7 0.1 3.7e-16 59.2 0.1 1.2 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 KIY64646.1 - 1e-06 28.5 0.0 1e-06 28.5 0.0 1.6 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain NPL4 PF05021.15 KIY64646.1 - 0.17 11.2 0.0 0.27 10.5 0.0 1.4 1 1 0 1 1 1 0 NPL4 family USP8_dimer PF08969.11 KIY64647.1 - 0.00046 20.4 0.1 0.00098 19.3 0.1 1.4 1 0 0 1 1 1 1 USP8 dimerisation domain GvpG PF05120.12 KIY64647.1 - 2.9 8.0 9.2 0.49 10.4 1.7 2.4 2 0 0 2 2 2 0 Gas vesicle protein G Histone PF00125.24 KIY64649.1 - 8.3e-10 39.1 0.0 9.4e-10 39.0 0.0 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 F-box-like PF12937.7 KIY64650.1 - 3.8e-06 26.7 0.9 9.3e-06 25.4 0.9 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY64650.1 - 0.65 9.9 2.9 0.93 9.5 1.3 2.2 2 0 0 2 2 2 0 F-box domain PNRC PF15365.6 KIY64651.1 - 0.00023 20.9 3.2 0.00023 20.9 3.2 3.1 3 0 0 3 3 3 1 Proline-rich nuclear receptor coactivator motif adh_short PF00106.25 KIY64652.1 - 5.4e-29 101.0 0.0 7.6e-29 100.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIY64652.1 - 1.4e-24 87.0 0.0 9.3e-24 84.3 0.0 2.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIY64652.1 - 2.6e-06 27.4 0.0 4.2e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 KR domain PALP PF00291.25 KIY64652.1 - 5.2e-05 22.8 0.0 7.3e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF1776 PF08643.10 KIY64652.1 - 0.0059 16.0 0.0 0.0075 15.7 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) RTA1 PF04479.13 KIY64653.1 - 8.3e-48 162.7 5.4 8.3e-48 162.7 5.4 1.3 1 1 0 1 1 1 1 RTA1 like protein DUF267 PF03268.14 KIY64653.1 - 0.34 9.7 3.8 0.17 10.8 0.4 1.9 2 0 0 2 2 2 0 Caenorhabditis protein of unknown function, DUF267 DAO PF01266.24 KIY64654.1 - 2.1e-41 142.7 0.2 2.7e-41 142.3 0.2 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KIY64654.1 - 0.00063 19.9 0.0 0.0013 18.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KIY64654.1 - 0.038 13.2 0.0 0.073 12.3 0.0 1.4 1 0 0 1 1 1 0 Thi4 family K_oxygenase PF13434.6 KIY64654.1 - 0.065 12.4 0.0 0.098 11.8 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) TMEM223 PF14640.6 KIY64654.1 - 0.11 12.6 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 223 MFS_1 PF07690.16 KIY64655.1 - 1e-41 143.1 46.3 2.6e-41 141.7 44.6 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIY64655.1 - 1.2e-15 57.4 10.2 1.2e-15 57.4 10.2 3.1 3 1 1 4 4 4 1 Sugar (and other) transporter GRAB PF10375.9 KIY64656.1 - 9.5e-07 28.5 1.8 1.8e-06 27.6 1.8 1.5 1 0 0 1 1 1 1 GRIP-related Arf-binding domain GldM_N PF12081.8 KIY64656.1 - 5.5e-05 23.4 16.3 0.0095 16.1 6.5 2.4 1 1 1 2 2 2 2 GldM N-terminal domain GRIP PF01465.20 KIY64656.1 - 0.0011 18.8 0.0 0.0027 17.6 0.0 1.7 1 0 0 1 1 1 1 GRIP domain ATG16 PF08614.11 KIY64656.1 - 0.0012 19.1 18.9 0.0012 19.1 18.9 3.0 2 1 1 3 3 2 1 Autophagy protein 16 (ATG16) MMPL PF03176.15 KIY64656.1 - 0.29 10.0 0.7 0.5 9.2 0.3 1.5 1 1 0 1 1 1 0 MMPL family RasGAP_C PF03836.15 KIY64656.1 - 0.36 11.0 20.1 2.3 8.4 6.8 2.7 2 0 0 2 2 2 0 RasGAP C-terminus Fez1 PF06818.15 KIY64656.1 - 0.46 10.9 47.3 0.42 11.0 8.9 3.1 1 1 2 3 3 3 0 Fez1 DUF1664 PF07889.12 KIY64656.1 - 0.66 10.0 15.5 3.4 7.7 2.5 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) MscS_porin PF12795.7 KIY64656.1 - 0.68 9.4 49.6 1.4 8.5 12.8 3.1 1 1 2 3 3 3 0 Mechanosensitive ion channel porin domain FliD_N PF02465.18 KIY64656.1 - 0.89 10.3 16.2 3 8.6 3.8 3.4 1 1 2 3 3 3 0 Flagellar hook-associated protein 2 N-terminus Golgin_A5 PF09787.9 KIY64656.1 - 4.8 6.6 50.8 0.071 12.6 11.2 2.6 1 1 1 2 2 2 0 Golgin subfamily A member 5 ERM PF00769.19 KIY64656.1 - 5 6.9 57.5 8.5 6.1 28.2 2.2 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Cob_adeno_trans PF01923.18 KIY64656.1 - 8 6.6 18.3 12 5.9 7.3 2.5 1 1 1 2 2 2 0 Cobalamin adenosyltransferase CFEM PF05730.11 KIY64657.1 - 6e-11 42.3 14.8 9.9e-11 41.6 14.8 1.4 1 0 0 1 1 1 1 CFEM domain BPS1 PF05633.11 KIY64657.1 - 5.6 5.9 8.5 6.2 5.7 8.5 1.1 1 0 0 1 1 1 0 Protein BYPASS1-related RTA1 PF04479.13 KIY64658.1 - 1.6e-45 155.2 9.0 2.1e-45 154.9 9.0 1.1 1 0 0 1 1 1 1 RTA1 like protein TMEM125 PF15109.6 KIY64658.1 - 3.1 8.2 7.7 1.3 9.4 0.5 2.7 2 1 1 3 3 3 0 TMEM125 protein family E1-E2_ATPase PF00122.20 KIY64658.1 - 4.3 6.8 5.1 5.9 6.4 1.3 2.3 2 0 0 2 2 2 0 E1-E2 ATPase DUF3754 PF12576.8 KIY64658.1 - 9.5 6.2 8.2 7 6.6 2.4 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3754) Plavaka PF18759.1 KIY64659.1 - 3.5e-65 220.3 0.0 4.2e-65 220.1 0.0 1.0 1 0 0 1 1 1 1 Plavaka transposase Plavaka PF18759.1 KIY64660.1 - 1.3e-16 60.8 0.1 1.5e-16 60.5 0.1 1.1 1 0 0 1 1 1 1 Plavaka transposase Nop14 PF04147.12 KIY64662.1 - 0.16 10.2 17.0 0.26 9.5 17.0 1.4 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 KIY64662.1 - 1.5 6.8 18.6 2.2 6.3 18.6 1.2 1 0 0 1 1 1 0 DNA polymerase phi TFIIF_alpha PF05793.12 KIY64662.1 - 5 5.6 35.0 0.22 10.1 29.1 1.8 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) p450 PF00067.22 KIY64663.1 - 2.3e-09 36.5 0.2 2.4e-09 36.5 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 Oxidored_FMN PF00724.20 KIY64664.1 - 1.1e-72 245.2 0.0 1.4e-72 244.9 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 KIY64664.1 - 0.033 13.3 0.0 0.066 12.3 0.0 1.4 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) F-box-like PF12937.7 KIY64665.1 - 1.3e-05 25.0 3.6 0.00011 22.1 0.2 3.3 3 0 0 3 3 3 1 F-box-like F-box-like PF12937.7 KIY64666.1 - 0.017 15.0 0.2 0.061 13.2 0.2 2.0 1 0 0 1 1 1 0 F-box-like Zn_clus PF00172.18 KIY64667.1 - 0.0036 17.4 13.8 0.0054 16.8 13.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SpoIIIAH PF12685.7 KIY64670.1 - 3.9 7.2 6.0 6.4 6.6 6.0 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein Aldedh PF00171.22 KIY64672.1 - 5.6e-84 282.3 0.0 7.4e-84 281.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family SNAD4 PF18750.1 KIY64675.1 - 0.0023 18.0 0.4 0.0032 17.6 0.4 1.2 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC4_like PF18774.1 KIY64675.1 - 0.064 13.2 0.2 0.08 12.9 0.2 1.2 1 0 0 1 1 1 0 APOBEC4-like -AID/APOBEC-deaminase Antimicrobial11 PF08106.11 KIY64677.1 - 0.072 13.1 0.2 0.33 11.0 0.2 2.2 1 0 0 1 1 1 0 Formaecin family SUa-2TM PF18179.1 KIY64677.1 - 0.087 12.1 0.9 0.11 11.8 0.1 1.5 2 0 0 2 2 2 0 SMODS- and Ubiquitin system-associated 2TM effector domain RR_TM4-6 PF06459.12 KIY64681.1 - 0.14 12.0 5.2 0.19 11.6 5.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF819 PF05684.12 KIY64681.1 - 0.17 10.9 0.0 0.26 10.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF819) HNH_2 PF13391.6 KIY64682.1 - 1.2e-08 35.0 0.0 2e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 HNH endonuclease UspB PF10625.9 KIY64683.1 - 0.093 12.7 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Universal stress protein B (UspB) Aldo_ket_red PF00248.21 KIY64684.1 - 1.3e-65 221.5 0.0 1.9e-65 221.0 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Bac_A_amyl_C PF18612.1 KIY64685.1 - 0.04 13.7 0.0 0.07 12.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial Alpha amylase C-terminal domain XPG_I_2 PF12813.7 KIY64689.1 - 0.15 11.5 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 XPG domain containing DNA_pol_delta_4 PF04081.13 KIY64691.1 - 9.8e-09 35.6 0.0 2.1e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase delta, subunit 4 zf-RING_UBOX PF13445.6 KIY64691.1 - 0.026 14.6 2.2 0.026 14.6 2.2 2.1 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KIY64691.1 - 0.034 14.3 2.7 0.05 13.8 0.2 2.4 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 KIY64691.1 - 0.84 9.6 9.1 2.9 7.9 9.1 1.9 1 1 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.25 KIY64691.1 - 4.2 7.3 9.2 20 5.2 9.2 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIY64691.1 - 6 7.3 9.9 27 5.2 9.9 2.2 1 1 0 1 1 1 0 Ring finger domain Prok-RING_4 PF14447.6 KIY64691.1 - 6.6 6.7 10.0 30 4.6 0.2 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 F-box-like PF12937.7 KIY64692.1 - 0.024 14.5 0.1 0.066 13.1 0.1 1.8 1 0 0 1 1 1 0 F-box-like DUF1256 PF06866.11 KIY64693.1 - 0.22 10.9 0.0 0.39 10.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1256) SSTK-IP PF15836.5 KIY64695.1 - 1 9.5 7.0 6.5 6.9 1.7 2.7 1 1 1 2 2 2 0 SSTK-interacting protein, TSSK6-activating co-chaperone protein KDZ PF18758.1 KIY64699.1 - 6.1e-53 179.7 0.2 1.1e-52 178.8 0.2 1.5 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KIY64699.1 - 1.6e-29 102.2 0.9 4e-29 100.9 0.1 2.1 2 0 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KIY64699.1 - 2.6e-05 24.3 0.0 7.2e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases KDZ PF18758.1 KIY64702.1 - 2.7e-73 246.3 0.1 5.2e-73 245.3 0.1 1.5 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Nsp2a_N PF17896.1 KIY64702.1 - 0.089 12.0 0.3 0.31 10.2 0.1 1.8 2 0 0 2 2 2 0 Replicase polyprotein 1a N-terminal domain SOG2 PF10428.9 KIY64703.1 - 0.69 9.0 10.8 0.43 9.7 8.6 1.7 2 0 0 2 2 2 0 RAM signalling pathway protein HMG_box_2 PF09011.10 KIY64704.1 - 8.6e-05 23.1 0.0 0.00027 21.5 0.0 1.9 1 0 0 1 1 1 1 HMG-box domain CsbD PF05532.12 KIY64704.1 - 9.5e-05 22.2 5.5 0.027 14.4 0.6 2.5 1 1 1 2 2 2 2 CsbD-like HMG_box PF00505.19 KIY64704.1 - 0.003 17.9 1.1 0.0086 16.5 0.0 2.3 2 0 0 2 2 2 1 HMG (high mobility group) box DUF2100 PF09873.9 KIY64705.1 - 0.07 13.0 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2100) RabGAP-TBC PF00566.18 KIY64707.1 - 1.2e-26 93.7 0.0 1.7e-26 93.2 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PLRV_ORF5 PF01690.17 KIY64707.1 - 0.0084 14.9 3.0 0.012 14.4 3.0 1.1 1 0 0 1 1 1 1 Potato leaf roll virus readthrough protein DUF3357 PF11837.8 KIY64707.1 - 0.022 15.2 0.0 0.069 13.6 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) DUF2721 PF11026.8 KIY64707.1 - 0.072 13.0 0.1 0.26 11.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) Vps39_2 PF10367.9 KIY64708.1 - 6.2e-10 39.5 0.0 1.7e-09 38.1 0.0 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.9 KIY64708.1 - 4.2e-07 30.2 1.1 1.8e-06 28.2 0.4 2.4 1 1 1 2 2 2 1 Vacuolar sorting protein 39 domain 1 Clathrin PF00637.20 KIY64708.1 - 0.029 14.2 0.4 0.14 12.0 0.1 2.2 2 0 0 2 2 2 0 Region in Clathrin and VPS CBM65_1 PF18259.1 KIY64709.1 - 0.09 12.9 0.0 0.14 12.3 0.0 1.4 1 1 0 1 1 1 0 Carbohydrate binding module 65 domain 1 Gti1_Pac2 PF09729.9 KIY64711.1 - 1.9e-45 155.2 0.1 1.1e-35 123.4 0.0 2.0 1 1 1 2 2 2 2 Gti1/Pac2 family Peptidase_M36 PF02128.15 KIY64714.1 - 2.2e-138 461.5 5.4 2.9e-138 461.1 5.4 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.13 KIY64714.1 - 1.3e-07 31.4 1.3 3.1e-07 30.1 1.3 1.6 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif DUF1202 PF06717.11 KIY64714.1 - 0.016 14.7 0.2 0.025 14.0 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1202) HHH_2 PF12826.7 KIY64714.1 - 0.14 12.3 0.0 0.4 10.8 0.0 1.7 2 0 0 2 2 2 0 Helix-hairpin-helix motif Terpene_synth_C PF03936.16 KIY64715.1 - 7.3e-06 25.5 0.0 1e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain RRM_1 PF00076.22 KIY64716.1 - 6.3e-37 125.2 0.0 8.7e-19 67.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Apolipoprotein PF01442.18 KIY64717.1 - 0.019 14.9 0.1 0.11 12.3 0.0 1.9 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Zn_clus PF00172.18 KIY64718.1 - 1.7e-05 24.9 9.6 3e-05 24.0 9.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CBS PF00571.28 KIY64720.1 - 4.9e-20 71.7 0.1 0.0003 21.1 0.1 4.4 4 0 0 4 4 4 4 CBS domain DUF3446 PF11928.8 KIY64720.1 - 0.025 14.9 0.6 0.076 13.3 0.6 1.8 1 0 0 1 1 1 0 Early growth response N-terminal domain DUF1453 PF07301.11 KIY64721.1 - 2.1 8.3 11.5 1.7 8.6 2.6 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF1453) DUF1146 PF06612.11 KIY64721.1 - 4.4 7.4 10.0 2.3 8.3 0.5 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1146) Fungal_trans PF04082.18 KIY64722.1 - 8.8e-29 100.4 0.1 1.8e-28 99.3 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY64722.1 - 6.9e-09 35.7 12.1 1.3e-08 34.9 12.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L44 PF00935.19 KIY64723.1 - 1.2e-37 128.3 11.7 1.8e-37 127.7 11.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 HMG-CoA_red PF00368.18 KIY64724.1 - 6.9e-139 462.9 3.0 9.3e-139 462.5 3.0 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Sterol-sensing PF12349.8 KIY64724.1 - 1.1e-10 41.6 0.7 2.8e-10 40.2 0.7 1.7 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 KIY64724.1 - 0.0012 17.1 0.6 0.0018 16.5 0.6 1.2 1 0 0 1 1 1 1 Patched family CAP PF00188.26 KIY64725.1 - 4.9e-20 72.6 0.4 5.6e-20 72.4 0.4 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family BTB PF00651.31 KIY64726.1 - 2.3e-05 24.6 0.0 7.1e-05 23.0 0.0 1.7 2 0 0 2 2 2 1 BTB/POZ domain ACOX PF01756.19 KIY64727.1 - 3.7e-38 130.9 0.0 6.3e-38 130.1 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 KIY64727.1 - 9.5e-14 52.0 0.0 1.6e-13 51.3 0.0 1.4 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 KIY64727.1 - 4.2e-10 39.7 0.0 1.7e-09 37.7 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 KIY64727.1 - 0.063 13.5 0.1 0.35 11.1 0.1 2.1 1 1 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain Zn_clus PF00172.18 KIY64728.1 - 3.6e-07 30.2 7.9 6.3e-07 29.4 7.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KIY64728.1 - 0.023 13.8 0.2 0.062 12.3 0.1 1.7 2 1 0 2 2 2 0 Fungal specific transcription factor domain ADH_N PF08240.12 KIY64729.1 - 7.4e-33 112.7 4.2 1.4e-32 111.9 4.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KIY64729.1 - 6.9e-17 61.6 0.0 2.1e-16 60.1 0.0 1.8 1 1 1 2 2 2 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KIY64729.1 - 9.5e-13 48.1 0.0 1.8e-12 47.2 0.0 1.5 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KIY64729.1 - 3.8e-07 31.2 0.0 5.7e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.19 KIY64729.1 - 0.0011 18.3 1.2 0.0016 17.8 1.2 1.2 1 0 0 1 1 1 1 FAD binding domain ADH_N_2 PF16884.5 KIY64729.1 - 0.014 15.3 0.0 0.13 12.1 0.0 2.2 2 0 0 2 2 2 0 N-terminal domain of oxidoreductase MAF_flag10 PF01973.18 KIY64729.1 - 0.08 12.6 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF115 Acetyltransf_3 PF13302.7 KIY64730.1 - 0.0007 20.3 0.0 0.0019 18.9 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF2569 PF10754.9 KIY64731.1 - 0.037 14.5 6.2 0.3 11.5 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2569) Metallothio_11 PF02066.15 KIY64731.1 - 0.049 13.8 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 Metallothionein family 11 ECH_1 PF00378.20 KIY64733.1 - 7.8e-30 104.0 0.0 1e-29 103.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KIY64733.1 - 4e-07 29.8 0.1 0.00091 18.8 0.0 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase ADH_N PF08240.12 KIY64734.1 - 4e-23 81.4 0.8 8.8e-23 80.3 0.8 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KIY64734.1 - 1.4e-16 60.6 0.1 5.7e-16 58.7 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KIY64734.1 - 0.00016 21.1 0.0 0.00025 20.4 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KIY64734.1 - 0.00042 19.7 0.0 0.00063 19.1 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 KIY64734.1 - 0.0035 17.3 0.0 0.0054 16.6 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 KIY64734.1 - 0.011 15.9 0.0 0.018 15.3 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ThiF PF00899.21 KIY64734.1 - 0.061 12.7 0.1 0.12 11.7 0.1 1.5 1 0 0 1 1 1 0 ThiF family GFO_IDH_MocA PF01408.22 KIY64734.1 - 0.064 14.1 0.0 0.11 13.3 0.0 1.3 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold ApbA PF02558.16 KIY64734.1 - 0.077 12.6 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.6 KIY64734.1 - 0.15 12.5 0.0 0.28 11.6 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding MIP PF00230.20 KIY64735.1 - 5.2e-45 153.9 8.6 6.4e-45 153.6 8.6 1.0 1 0 0 1 1 1 1 Major intrinsic protein DZR PF12773.7 KIY64736.1 - 0.077 13.0 0.4 0.18 11.9 0.4 1.6 1 1 0 1 1 1 0 Double zinc ribbon zf-HIT PF04438.16 KIY64736.1 - 1.4 8.8 5.9 0.12 12.3 0.7 1.8 2 0 0 2 2 2 0 HIT zinc finger TT_ORF2 PF02957.15 KIY64736.1 - 1.7 9.6 5.6 0.26 12.2 1.4 1.9 2 0 0 2 2 2 0 TT viral ORF2 Glyco_hydro_18 PF00704.28 KIY64737.1 - 1.4e-74 251.6 5.6 1.7e-74 251.4 5.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 ADH_zinc_N PF00107.26 KIY64738.1 - 1.3e-20 73.7 0.0 1.9e-20 73.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KIY64738.1 - 1.7e-17 63.3 0.0 3.8e-17 62.1 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 KIY64738.1 - 2e-08 35.3 0.0 3.8e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glyco_hydro_18 PF00704.28 KIY64739.1 - 6.7e-88 295.4 0.1 7.7e-88 295.2 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 p450 PF00067.22 KIY64740.1 - 1.6e-64 218.4 0.0 2e-64 218.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 VSG_B PF13206.6 KIY64741.1 - 0.17 11.1 4.7 0.23 10.7 4.7 1.1 1 0 0 1 1 1 0 Trypanosomal VSG domain TIG PF01833.24 KIY64742.1 - 0.094 12.8 0.1 0.11 12.6 0.1 1.1 1 0 0 1 1 1 0 IPT/TIG domain TBP PF00352.21 KIY64743.1 - 7.7e-49 163.6 0.3 5e-32 109.7 0.0 2.0 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 KIY64743.1 - 0.00016 21.7 0.0 0.52 10.5 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) Peptidase_S32 PF05579.13 KIY64744.1 - 0.00025 20.4 0.0 0.00043 19.6 0.0 1.3 1 0 0 1 1 1 1 Equine arteritis virus serine endopeptidase S32 Trypsin_2 PF13365.6 KIY64744.1 - 0.0058 17.5 0.1 1.4 9.8 0.0 2.5 2 1 0 2 2 2 1 Trypsin-like peptidase domain Peptidase_S3 PF00944.19 KIY64744.1 - 0.012 15.4 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 Alphavirus core protein Peptidase_S7 PF00949.21 KIY64744.1 - 0.042 13.7 0.1 0.096 12.5 0.1 1.5 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease Peptidase_S64 PF08192.11 KIY64744.1 - 0.075 11.5 0.0 0.11 10.9 0.0 1.1 1 0 0 1 1 1 0 Peptidase family S64 Trypsin PF00089.26 KIY64744.1 - 0.12 12.2 0.3 0.31 10.8 0.0 1.8 3 0 0 3 3 3 0 Trypsin Tim17 PF02466.19 KIY64745.1 - 0.0063 16.9 3.1 0.032 14.6 0.1 2.2 2 0 0 2 2 2 2 Tim17/Tim22/Tim23/Pmp24 family CHAT PF12770.7 KIY64746.1 - 4.4e-30 105.1 0.0 6.6e-30 104.5 0.0 1.2 1 0 0 1 1 1 1 CHAT domain Sel1 PF08238.12 KIY64746.1 - 0.035 14.8 0.1 1.2 10.0 0.0 2.9 3 0 0 3 3 3 0 Sel1 repeat TPR_11 PF13414.6 KIY64746.1 - 0.037 13.7 0.0 0.36 10.6 0.0 2.4 2 0 0 2 2 2 0 TPR repeat TPR_2 PF07719.17 KIY64746.1 - 0.09 12.9 0.0 10 6.5 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 KIY64746.1 - 0.091 12.7 0.0 1.1 9.2 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Dynamin_M PF01031.20 KIY64747.1 - 1.4e-100 336.2 0.0 3e-100 335.1 0.0 1.6 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 KIY64747.1 - 5.3e-54 182.8 0.0 1e-53 181.8 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 KIY64747.1 - 2.6e-29 101.2 2.4 2.6e-29 101.2 2.4 1.8 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KIY64747.1 - 0.00034 20.7 0.1 0.0022 18.1 0.0 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase zf-H2C2_5 PF13909.6 KIY64748.1 - 6.4e-15 54.6 9.8 4.2e-05 23.2 0.2 3.5 3 0 0 3 3 3 3 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 KIY64748.1 - 2.6e-13 49.6 14.3 3.2e-05 24.1 1.0 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIY64748.1 - 2.5e-08 34.1 13.3 0.00075 20.1 0.4 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-Di19 PF05605.12 KIY64748.1 - 3.6e-06 27.2 9.5 0.00083 19.6 3.3 2.4 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 KIY64748.1 - 0.00022 21.5 19.6 0.046 14.2 0.1 3.7 4 0 0 4 4 3 2 Zinc-finger double domain GAGA PF09237.11 KIY64748.1 - 0.00078 19.2 1.5 0.9 9.4 0.0 3.3 3 0 0 3 3 3 1 GAGA factor zf-BED PF02892.15 KIY64748.1 - 0.0038 17.2 9.7 0.37 10.9 1.7 2.8 2 1 1 3 3 3 2 BED zinc finger IBR PF01485.21 KIY64748.1 - 0.0049 17.1 3.0 0.0049 17.1 3.0 2.1 1 1 1 2 2 2 1 IBR domain, a half RING-finger domain zf_C2H2_ZHX PF18387.1 KIY64748.1 - 0.012 15.2 6.5 1.8 8.3 0.1 3.2 1 1 2 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_2 PF12756.7 KIY64748.1 - 0.017 15.5 8.3 0.6 10.5 0.3 3.1 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 KIY64748.1 - 0.088 13.1 2.3 0.19 12.1 0.0 2.4 3 0 0 3 3 2 0 Zinc-finger double-stranded RNA-binding ROS_MUCR PF05443.11 KIY64748.1 - 0.12 12.5 0.6 0.3 11.2 0.6 1.7 1 1 0 1 1 1 0 ROS/MUCR transcriptional regulator protein Zn_Tnp_IS1595 PF12760.7 KIY64748.1 - 0.13 12.3 4.0 0.44 10.6 1.9 2.3 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-met PF12874.7 KIY64748.1 - 0.13 12.7 0.2 0.46 10.9 0.0 2.0 2 0 0 2 2 1 0 Zinc-finger of C2H2 type OrsD PF12013.8 KIY64748.1 - 0.16 12.4 9.4 0.87 10.0 0.5 3.1 2 1 1 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D CpXC PF14353.6 KIY64748.1 - 0.44 10.6 4.6 6.5 6.8 0.6 2.6 1 1 2 3 3 3 0 CpXC protein zf-ribbon_3 PF13248.6 KIY64748.1 - 0.91 9.0 5.5 8 6.0 0.0 3.1 4 0 0 4 4 3 0 zinc-ribbon domain zinc_ribbon_9 PF14369.6 KIY64748.1 - 1.5 9.2 5.3 8.2 6.8 0.3 2.8 3 0 0 3 3 2 0 zinc-ribbon FOXP-CC PF16159.5 KIY64748.1 - 1.9 9.2 5.4 3 8.6 0.6 2.9 1 1 2 3 3 3 0 FOXP coiled-coil domain PolC_DP2 PF03833.13 KIY64748.1 - 2.2 6.0 4.2 2.9 5.6 4.2 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Ribosomal_L37ae PF01780.19 KIY64748.1 - 4 7.6 5.2 11 6.2 0.5 2.4 1 1 1 2 2 2 0 Ribosomal L37ae protein family Pkinase_fungal PF17667.1 KIY64749.1 - 2.3e-09 36.6 0.1 2.6e-09 36.3 0.1 1.0 1 0 0 1 1 1 1 Fungal protein kinase Shugoshin_N PF07558.11 KIY64750.1 - 1.1e-09 38.0 3.2 2.5e-09 36.8 3.2 1.6 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.11 KIY64750.1 - 1.9e-09 37.1 5.2 1.9e-09 37.1 5.2 3.3 4 0 0 4 4 4 1 Shugoshin C terminus TMPIT PF07851.13 KIY64750.1 - 0.67 9.1 1.8 1.1 8.4 1.8 1.3 1 0 0 1 1 1 0 TMPIT-like protein TelA PF05816.11 KIY64750.1 - 1 8.4 6.4 3.3 6.7 2.8 2.1 2 0 0 2 2 2 0 Toxic anion resistance protein (TelA) ZapB PF06005.12 KIY64750.1 - 2.6 8.5 7.7 6.9 7.2 7.7 1.7 1 0 0 1 1 1 0 Cell division protein ZapB p450 PF00067.22 KIY64751.1 - 2.8e-48 164.8 0.0 5.1e-48 164.0 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.25 KIY64752.1 - 1.9e-42 145.4 0.0 8.8e-22 77.7 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIY64752.1 - 8e-14 51.5 1.0 1e-07 31.6 0.2 2.8 2 1 0 2 2 2 2 Protein tyrosine kinase PrmA PF06325.13 KIY64752.1 - 0.078 12.4 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Pox_ser-thr_kin PF05445.11 KIY64752.1 - 0.17 10.8 0.0 0.24 10.3 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.22 KIY64752.1 - 0.19 11.3 0.1 0.52 9.9 0.1 1.7 1 0 0 1 1 1 0 RIO1 family F-box-like PF12937.7 KIY64753.1 - 6.6e-06 25.9 0.0 2.1e-05 24.3 0.0 1.9 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KIY64753.1 - 0.0012 19.2 0.1 0.45 11.0 0.3 3.9 4 0 0 4 4 4 1 Leucine Rich repeats (2 copies) F-box PF00646.33 KIY64753.1 - 0.013 15.3 0.0 0.069 13.1 0.0 2.3 1 1 0 1 1 1 0 F-box domain F-box-like PF12937.7 KIY64754.1 - 4.7e-08 32.8 0.9 1.3e-07 31.4 0.1 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIY64754.1 - 0.026 14.4 0.0 0.097 12.6 0.0 2.0 1 0 0 1 1 1 0 F-box domain Cwf_Cwc_15 PF04889.12 KIY64757.1 - 0.14 11.9 12.5 0.24 11.1 12.5 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PGA2 PF07543.12 KIY64757.1 - 1.2 9.1 11.0 2.4 8.1 11.0 1.5 1 0 0 1 1 1 0 Protein trafficking PGA2 RNA_pol_3_Rpc31 PF11705.8 KIY64757.1 - 2.8 8.1 17.3 6.3 7.0 17.3 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 FAM60A PF15396.6 KIY64757.1 - 7 6.6 6.9 1.7 8.6 3.2 1.7 2 0 0 2 2 2 0 Protein Family FAM60A FAD_oxidored PF12831.7 KIY64759.1 - 3e-05 23.6 0.0 0.087 12.2 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KIY64759.1 - 0.0015 17.4 0.1 3.6 6.3 0.0 3.1 3 0 0 3 3 3 2 Tryptophan halogenase DAO PF01266.24 KIY64759.1 - 0.021 14.4 0.3 3.1 7.3 0.1 2.5 2 1 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIY64759.1 - 0.14 11.3 0.1 0.61 9.3 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KIY64760.1 - 1e-61 208.8 1.8 1.4e-61 208.3 1.8 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KIY64760.1 - 9.9e-35 119.1 1.6 5e-34 116.9 0.2 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KIY64760.1 - 3.3e-19 69.2 10.0 2.1e-17 63.4 3.1 2.7 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KIY64760.1 - 8.4e-12 45.0 0.4 2.7e-10 40.0 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KIY64760.1 - 9.8e-07 28.5 0.5 2.3e-05 24.0 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KIY64760.1 - 4.2e-05 23.7 0.2 0.00013 22.1 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KIY64760.1 - 0.00013 20.8 4.9 0.017 13.8 0.3 2.5 2 1 0 2 2 2 2 HI0933-like protein DAO PF01266.24 KIY64760.1 - 0.00014 21.5 10.7 0.0013 18.4 0.0 3.3 2 1 1 3 3 3 2 FAD dependent oxidoreductase GIDA PF01134.22 KIY64760.1 - 0.00041 19.5 4.4 0.00051 19.2 0.3 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 KIY64760.1 - 0.0046 16.3 1.7 0.25 10.6 0.4 2.5 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 KIY64760.1 - 0.0047 16.0 2.9 0.031 13.4 0.7 2.4 2 0 0 2 2 2 1 FAD binding domain NAD_binding_7 PF13241.6 KIY64760.1 - 0.0081 16.6 0.4 3.6 8.1 0.3 2.5 2 0 0 2 2 2 1 Putative NAD(P)-binding K_oxygenase PF13434.6 KIY64760.1 - 0.013 14.6 0.3 0.033 13.4 0.0 1.8 2 1 2 4 4 4 0 L-lysine 6-monooxygenase (NADPH-requiring) 2-Hacid_dh_C PF02826.19 KIY64760.1 - 0.025 13.9 2.1 0.35 10.2 0.3 2.5 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 KIY64760.1 - 0.052 13.4 6.1 0.7 9.7 1.0 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 KIY64760.1 - 0.76 10.0 2.7 31 4.9 0.8 2.4 2 0 0 2 2 2 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 KIY64760.1 - 1.2 8.7 4.3 0.35 10.4 1.0 1.8 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_oxidored PF12831.7 KIY64761.1 - 0.00038 19.9 0.0 0.0033 16.9 0.0 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KIY64761.1 - 0.17 12.5 0.0 0.53 10.9 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF3373 PF11853.8 KIY64763.1 - 0.028 13.6 0.0 0.038 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) Gp_dh_C PF02800.20 KIY64767.1 - 3.5e-70 234.6 0.1 5e-70 234.2 0.1 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 KIY64767.1 - 5.4e-37 126.2 0.0 1.2e-36 125.1 0.0 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain F-box-like PF12937.7 KIY64769.1 - 1.8e-06 27.7 4.3 2.9e-06 27.1 2.1 2.3 2 0 0 2 2 2 1 F-box-like ThrE PF06738.12 KIY64770.1 - 0.06 12.7 5.1 0.087 12.2 5.1 1.1 1 0 0 1 1 1 0 Putative threonine/serine exporter F-box-like PF12937.7 KIY64772.1 - 2.2e-07 30.7 0.0 6.6e-07 29.1 0.0 1.9 1 0 0 1 1 1 1 F-box-like HOOK PF05622.12 KIY64772.1 - 0.09 10.9 0.0 0.12 10.5 0.0 1.0 1 0 0 1 1 1 0 HOOK protein AIM3 PF17096.5 KIY64773.1 - 2.1 9.3 6.3 3.8 8.5 6.3 1.4 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 p450 PF00067.22 KIY64777.1 - 4e-71 240.1 0.0 5.3e-71 239.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SelP_N PF04592.14 KIY64779.1 - 0.11 11.9 18.8 0.18 11.2 18.8 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Zip PF02535.22 KIY64779.1 - 0.57 9.3 5.2 0.72 9.0 5.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF755 PF05501.11 KIY64779.1 - 1.2 9.5 10.1 2.1 8.6 10.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) CAF20 PF17052.5 KIY64779.1 - 1.3 9.2 5.5 2.7 8.1 5.5 1.5 1 0 0 1 1 1 0 Cap associated factor CUE PF02845.16 KIY64782.1 - 3.6e-06 26.6 0.0 5.3e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 CUE domain Lon_C PF05362.13 KIY64783.1 - 1.4e-63 214.2 1.7 2e-63 213.7 1.7 1.2 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 KIY64783.1 - 8.8e-21 74.7 0.0 1.9e-20 73.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) LON_substr_bdg PF02190.16 KIY64783.1 - 7.4e-11 42.3 0.0 1.6e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA_5 PF07728.14 KIY64783.1 - 1e-08 35.3 0.0 2e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 KIY64783.1 - 8.8e-07 28.8 0.7 1.7e-06 27.8 0.1 1.9 2 1 0 2 2 1 1 Subunit ChlI of Mg-chelatase AAA_2 PF07724.14 KIY64783.1 - 7.3e-06 26.2 0.0 2.2e-05 24.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KIY64783.1 - 0.0011 19.4 3.9 0.0066 16.9 0.0 3.0 2 2 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 KIY64783.1 - 0.0019 18.0 0.1 0.01 15.6 0.0 2.2 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 KIY64783.1 - 0.013 15.4 0.0 0.034 14.0 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KIY64783.1 - 0.023 14.9 0.0 0.046 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KIY64783.1 - 0.03 14.2 0.0 0.061 13.2 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_22 PF13401.6 KIY64783.1 - 0.031 14.6 1.7 0.37 11.0 0.1 3.3 3 1 0 3 3 3 0 AAA domain NACHT PF05729.12 KIY64783.1 - 0.048 13.6 0.0 1.9 8.4 0.0 2.4 2 0 0 2 2 2 0 NACHT domain TIP49 PF06068.13 KIY64783.1 - 0.1 11.8 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain RNA_helicase PF00910.22 KIY64783.1 - 0.13 12.6 0.0 0.3 11.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase LysM PF01476.20 KIY64786.1 - 0.00055 19.9 0.0 0.0011 18.9 0.0 1.5 1 0 0 1 1 1 1 LysM domain zf-RING_5 PF14634.6 KIY64786.1 - 0.56 10.2 9.0 0.98 9.4 9.0 1.4 1 0 0 1 1 1 0 zinc-RING finger domain AAA_30 PF13604.6 KIY64787.1 - 1.2e-08 34.9 0.0 1.4e-08 34.7 0.0 1.0 1 0 0 1 1 1 1 AAA domain PIF1 PF05970.14 KIY64787.1 - 1.4e-08 34.4 0.0 1.5e-08 34.2 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_19 PF13245.6 KIY64787.1 - 8e-05 23.0 0.1 0.00012 22.5 0.1 1.3 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KIY64787.1 - 0.0069 16.7 0.0 0.025 14.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 KIY64787.1 - 0.018 14.8 0.0 0.021 14.5 0.0 1.1 1 0 0 1 1 1 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 KIY64787.1 - 0.022 14.0 0.0 0.033 13.5 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin TMP_2 PF06791.13 KIY64787.1 - 0.071 12.8 0.4 0.084 12.5 0.4 1.1 1 0 0 1 1 1 0 Prophage tail length tape measure protein IstB_IS21 PF01695.17 KIY64787.1 - 0.083 12.6 0.2 0.54 10.0 0.2 2.0 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_16 PF13191.6 KIY64787.1 - 0.11 12.9 0.0 0.18 12.2 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain Adeno_IVa2 PF02456.15 KIY64787.1 - 0.17 10.7 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein Lon_2 PF13337.6 KIY64787.1 - 0.21 10.1 0.0 0.34 9.4 0.0 1.3 1 0 0 1 1 1 0 Putative ATP-dependent Lon protease PIF1 PF05970.14 KIY64788.1 - 0.0022 17.3 0.0 0.0026 17.0 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase YadA_anchor PF03895.15 KIY64788.1 - 0.0072 16.4 0.1 0.019 15.1 0.1 1.7 1 0 0 1 1 1 1 YadA-like membrane anchor domain Prefoldin PF02996.17 KIY64791.1 - 0.036 14.0 0.1 0.053 13.4 0.1 1.2 1 0 0 1 1 1 0 Prefoldin subunit CR6_interact PF10147.9 KIY64791.1 - 0.062 13.0 5.0 0.076 12.7 5.0 1.0 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 FUSC PF04632.12 KIY64791.1 - 8.8 4.7 12.4 9.8 4.6 12.4 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family AA_permease_2 PF13520.6 KIY64792.1 - 3.1e-67 227.3 55.2 3.8e-67 227.0 55.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KIY64792.1 - 5.1e-16 58.3 49.4 7.2e-16 57.8 49.4 1.1 1 0 0 1 1 1 1 Amino acid permease Zn_clus PF00172.18 KIY64793.1 - 2.9e-07 30.5 13.9 6.2e-07 29.4 13.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KIY64793.1 - 0.00021 20.4 0.1 0.0005 19.2 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain NAD_binding_10 PF13460.6 KIY64796.1 - 5.3e-09 36.2 0.0 0.00042 20.2 0.0 2.1 2 0 0 2 2 2 2 NAD(P)H-binding adh_short_C2 PF13561.6 KIY64796.1 - 0.00013 21.6 0.0 0.00019 21.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIY64796.1 - 0.0011 18.5 0.0 0.0014 18.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Fungal_trans PF04082.18 KIY64797.1 - 1.1e-24 86.9 2.2 1.3e-24 86.7 0.3 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY64797.1 - 4.1e-08 33.2 6.8 7.9e-08 32.3 6.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FMO-like PF00743.19 KIY64798.1 - 3.6e-27 95.0 0.0 3.7e-17 62.0 0.0 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KIY64798.1 - 3.4e-15 56.1 0.0 3.7e-12 46.1 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KIY64798.1 - 4e-14 52.5 0.0 2.5e-12 46.6 0.0 2.7 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIY64798.1 - 1.4e-09 38.0 1.1 3.8e-09 36.7 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KIY64798.1 - 1.5e-08 34.2 0.2 8.8e-07 28.4 0.0 2.7 2 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KIY64798.1 - 2.1e-07 31.1 2.8 0.00087 19.3 0.2 4.2 3 1 0 3 3 3 1 FAD-NAD(P)-binding Amino_oxidase PF01593.24 KIY64798.1 - 2.6e-07 30.3 0.1 0.00035 20.0 0.0 2.6 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase Thi4 PF01946.17 KIY64798.1 - 1.8e-06 27.4 0.0 0.00067 19.0 0.0 2.2 2 0 0 2 2 2 2 Thi4 family DAO PF01266.24 KIY64798.1 - 4.4e-06 26.5 7.2 0.00033 20.3 0.0 3.6 3 1 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KIY64798.1 - 0.00023 20.4 0.0 0.00047 19.4 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 KIY64798.1 - 0.0014 18.0 0.1 0.0028 17.0 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain Glu_dehyd_C PF16912.5 KIY64798.1 - 0.0067 15.9 0.0 0.18 11.3 0.0 2.2 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus Shikimate_DH PF01488.20 KIY64798.1 - 0.011 15.9 0.0 3.8 7.6 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Malic_M PF03949.15 KIY64798.1 - 0.014 14.7 0.0 0.024 13.9 0.0 1.3 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain HI0933_like PF03486.14 KIY64798.1 - 0.016 13.9 0.0 0.033 12.9 0.0 1.5 1 0 0 1 1 1 0 HI0933-like protein AlaDh_PNT_C PF01262.21 KIY64798.1 - 0.017 14.4 0.0 0.057 12.7 0.0 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 KIY64798.1 - 0.025 15.1 0.2 3 8.5 0.1 3.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KIY64798.1 - 0.12 12.8 0.0 27 5.3 0.0 2.8 3 0 0 3 3 3 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 KIY64798.1 - 0.16 11.3 0.0 3.2 7.1 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 KIY64798.1 - 0.41 10.5 1.0 1.1 9.1 0.1 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Abhydrolase_1 PF00561.20 KIY64800.1 - 4.1e-13 49.6 0.0 2.3e-09 37.3 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIY64800.1 - 6.4e-13 48.5 0.0 7.9e-10 38.4 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 BAAT_C PF08840.11 KIY64800.1 - 6.7e-08 32.7 0.0 0.00039 20.4 0.0 2.2 2 0 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_6 PF12697.7 KIY64800.1 - 1.7e-07 32.1 0.0 3.7e-05 24.4 0.0 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KIY64800.1 - 0.00015 21.7 0.1 0.12 12.2 0.0 2.7 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase DLH PF01738.18 KIY64800.1 - 0.00015 21.4 0.0 0.0021 17.6 0.0 2.3 2 1 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 KIY64800.1 - 0.00062 19.3 0.0 0.0024 17.4 0.0 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family LIP PF03583.14 KIY64800.1 - 0.029 13.7 0.0 0.059 12.7 0.0 1.5 2 0 0 2 2 2 0 Secretory lipase Abhydro_lipase PF04083.16 KIY64800.1 - 0.04 13.5 0.0 0.1 12.2 0.0 1.6 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region AXE1 PF05448.12 KIY64800.1 - 0.13 10.9 0.0 0.52 8.9 0.0 1.8 1 1 1 2 2 2 0 Acetyl xylan esterase (AXE1) UQ_con PF00179.26 KIY64802.1 - 1.7e-47 160.6 0.0 1.9e-47 160.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KIY64802.1 - 0.0008 19.1 0.0 0.001 18.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 KIY64802.1 - 0.0087 15.9 0.1 0.017 14.9 0.1 1.5 1 1 0 1 1 1 1 UEV domain RWD PF05773.22 KIY64802.1 - 0.11 12.7 0.1 0.2 11.9 0.1 1.4 1 1 0 1 1 1 0 RWD domain bZIP_1 PF00170.21 KIY64803.1 - 0.0011 19.1 12.8 0.0018 18.3 12.8 1.5 1 1 0 1 1 1 1 bZIP transcription factor DUF2397 PF09660.10 KIY64803.1 - 0.024 13.6 4.2 0.03 13.2 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2397) bZIP_2 PF07716.15 KIY64803.1 - 0.048 13.8 12.3 0.14 12.3 12.3 1.8 1 1 0 1 1 1 0 Basic region leucine zipper bZIP_Maf PF03131.17 KIY64804.1 - 0.0023 18.4 6.5 0.0023 18.4 6.5 1.6 2 0 0 2 2 2 1 bZIP Maf transcription factor Casc1_N PF15927.5 KIY64804.1 - 0.0069 16.1 10.4 0.012 15.3 10.4 1.3 1 0 0 1 1 1 1 Cancer susceptibility candidate 1 N-terminus bZIP_1 PF00170.21 KIY64804.1 - 0.0092 16.1 10.8 0.019 15.1 10.8 1.5 1 0 0 1 1 1 1 bZIP transcription factor Jnk-SapK_ap_N PF09744.9 KIY64804.1 - 0.015 15.6 3.1 0.015 15.6 3.1 1.4 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 GHMP_kinases_C PF08544.13 KIY64804.1 - 0.02 15.2 0.6 0.27 11.6 0.0 2.2 2 1 0 2 2 2 0 GHMP kinases C terminal Mod_r PF07200.13 KIY64804.1 - 0.21 11.7 5.5 0.035 14.2 2.0 1.5 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein bZIP_2 PF07716.15 KIY64805.1 - 0.0069 16.4 1.2 0.012 15.7 1.2 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KIY64805.1 - 0.035 14.2 0.5 0.06 13.5 0.5 1.3 1 0 0 1 1 1 0 bZIP transcription factor ZapB PF06005.12 KIY64805.1 - 0.078 13.4 0.2 0.14 12.6 0.2 1.4 1 1 0 1 1 1 0 Cell division protein ZapB Prefoldin PF02996.17 KIY64806.1 - 0.079 12.9 0.0 0.38 10.7 0.0 1.9 2 0 0 2 2 2 0 Prefoldin subunit Glyco_hyd_65N_2 PF14498.6 KIY64807.1 - 1.3e-50 172.5 0.3 2.6e-50 171.5 0.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain p450 PF00067.22 KIY64808.1 - 4.9e-71 239.9 0.0 5.6e-71 239.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.18 KIY64810.1 - 9.7e-05 22.4 5.6 0.00021 21.4 5.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KIY64810.1 - 0.0055 15.8 0.1 0.014 14.5 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain PGM_PMM_I PF02878.16 KIY64811.1 - 4e-16 59.0 0.7 2.8e-07 30.3 0.0 3.0 2 1 1 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 KIY64811.1 - 4.7e-10 39.5 0.4 2.1e-09 37.4 0.3 2.2 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_II PF02879.16 KIY64811.1 - 0.014 16.0 0.0 0.09 13.4 0.0 2.5 2 1 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 KIY64811.1 - 0.045 14.0 0.2 0.11 12.7 0.2 1.7 1 1 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III SNAP PF14938.6 KIY64812.1 - 2.9e-108 361.6 18.1 3.3e-108 361.4 18.1 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_6 PF13174.6 KIY64812.1 - 0.0018 18.8 12.2 20 6.1 0.1 6.1 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 KIY64812.1 - 0.0029 17.5 9.5 1.2 9.3 0.2 5.2 4 1 1 5 5 5 1 Tetratricopeptide repeat Spatacsin_C PF14649.6 KIY64812.1 - 0.0074 15.4 6.1 0.065 12.3 0.5 2.2 2 0 0 2 2 2 2 Spatacsin C-terminus TC1 PF15063.6 KIY64812.1 - 0.012 15.4 0.8 0.88 9.5 0.1 2.5 2 0 0 2 2 2 0 Thyroid cancer protein 1 TPR_12 PF13424.6 KIY64812.1 - 0.019 15.2 20.2 0.46 10.8 3.6 4.1 1 1 4 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 KIY64812.1 - 0.4 10.9 22.6 30 5.1 0.7 6.5 5 2 2 7 7 7 0 Tetratricopeptide repeat NSF PF02071.20 KIY64812.1 - 0.55 11.2 18.6 2.8 9.1 0.3 6.6 5 1 0 5 5 5 0 Aromatic-di-Alanine (AdAR) repeat TPR_11 PF13414.6 KIY64812.1 - 0.64 9.8 16.0 2.1 8.1 0.1 5.5 6 1 1 7 7 7 0 TPR repeat DAO PF01266.24 KIY64814.1 - 4.5e-26 92.3 0.0 5.3e-26 92.0 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIY64814.1 - 1e-07 31.5 0.2 2.2e-06 27.1 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KIY64814.1 - 2.5e-06 27.9 0.0 5e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding NAD_binding_8 PF13450.6 KIY64814.1 - 8.6e-06 25.9 0.2 2.2e-05 24.6 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KIY64814.1 - 0.0001 22.8 0.0 0.00032 21.2 0.0 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KIY64814.1 - 0.00025 20.3 0.1 0.0005 19.3 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 KIY64814.1 - 0.0015 17.8 0.2 0.0033 16.7 0.2 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 KIY64814.1 - 0.0041 16.4 0.0 0.0085 15.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 KIY64814.1 - 0.005 16.0 0.1 0.0092 15.1 0.1 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 KIY64814.1 - 0.013 14.3 0.0 0.02 13.6 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 KIY64814.1 - 0.018 14.3 0.0 0.041 13.1 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KIY64814.1 - 0.078 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Amino_oxidase PF01593.24 KIY64814.1 - 0.089 12.1 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Ribosomal_L36 PF00444.18 KIY64815.1 - 2.6e-21 75.5 11.0 3.3e-21 75.2 11.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L36 Abhydrolase_4 PF08386.10 KIY64817.1 - 1e-06 28.8 0.0 2.1e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Serpentine_r_xa PF03383.15 KIY64818.1 - 0.17 11.8 0.1 0.27 11.2 0.1 1.2 1 0 0 1 1 1 0 Caenorhabditis serpentine receptor-like protein, class xa PMP1_2 PF08114.11 KIY64819.1 - 0.03 14.1 0.2 0.05 13.4 0.2 1.3 1 0 0 1 1 1 0 ATPase proteolipid family OppC_N PF12911.7 KIY64819.1 - 0.04 13.9 2.2 0.1 12.6 2.2 1.7 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Myosin_head PF00063.21 KIY64820.1 - 1.7e-218 727.2 0.0 3.8e-218 726.0 0.0 1.5 1 1 0 1 1 1 1 Myosin head (motor domain) Myosin_N PF02736.19 KIY64820.1 - 0.0037 17.1 1.8 0.0083 15.9 1.8 1.6 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain PhoH PF02562.16 KIY64820.1 - 0.016 14.7 0.1 0.032 13.7 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_16 PF13191.6 KIY64820.1 - 0.024 15.0 0.0 0.061 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KIY64820.1 - 0.038 14.3 0.0 0.12 12.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KIY64820.1 - 0.047 13.4 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain APS_kinase PF01583.20 KIY64820.1 - 0.06 13.2 0.3 0.18 11.7 0.0 1.9 2 0 0 2 2 2 0 Adenylylsulphate kinase ABC_tran PF00005.27 KIY64820.1 - 0.091 13.3 0.0 0.21 12.1 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.12 KIY64820.1 - 0.1 11.9 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin RsgA_GTPase PF03193.16 KIY64820.1 - 0.13 12.2 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase DUF722 PF05263.11 KIY64820.1 - 0.15 12.3 0.0 0.49 10.6 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF722) Integrin_alpha PF00357.20 KIY64821.1 - 0.0069 16.3 1.5 0.032 14.2 1.5 2.3 1 1 0 1 1 1 1 Integrin alpha cytoplasmic region Ras PF00071.22 KIY64823.1 - 2.4e-52 176.8 0.0 3e-52 176.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIY64823.1 - 3.8e-32 111.0 0.0 5.6e-32 110.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIY64823.1 - 7.2e-13 48.4 0.0 9.3e-13 48.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KIY64823.1 - 2.5e-06 27.2 0.0 0.00014 21.5 0.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KIY64823.1 - 0.00013 21.4 0.0 0.00015 21.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KIY64823.1 - 0.0002 21.4 0.0 0.00027 21.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KIY64823.1 - 0.00066 19.2 0.0 0.00096 18.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 KIY64823.1 - 0.0071 15.9 0.0 0.01 15.3 0.0 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region NACHT PF05729.12 KIY64823.1 - 0.0093 15.9 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 NACHT domain RsgA_GTPase PF03193.16 KIY64823.1 - 0.01 15.8 0.0 3 7.7 0.0 2.2 1 1 1 2 2 2 0 RsgA GTPase DAP3 PF10236.9 KIY64823.1 - 0.011 15.0 0.0 0.022 14.0 0.0 1.4 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 ABC_tran PF00005.27 KIY64823.1 - 0.013 16.1 0.2 0.038 14.5 0.2 1.9 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 KIY64823.1 - 0.021 15.2 0.3 0.061 13.7 0.2 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KIY64823.1 - 0.025 14.9 0.0 0.036 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 KIY64823.1 - 0.027 14.2 0.0 4.7 6.9 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Septin PF00735.18 KIY64823.1 - 0.065 12.5 0.0 0.13 11.5 0.0 1.4 2 0 0 2 2 2 0 Septin ATPase PF06745.13 KIY64823.1 - 0.069 12.5 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 KaiC AAA_29 PF13555.6 KIY64823.1 - 0.076 12.8 0.0 0.19 11.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain D-ser_dehydrat PF14031.6 KIY64824.1 - 2.3e-25 89.0 0.2 7.7e-25 87.4 0.0 2.0 2 1 0 2 2 2 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 KIY64824.1 - 1.3e-12 47.9 0.0 1.8e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Ribonuc_L-PSP PF01042.21 KIY64825.1 - 2.4e-32 111.5 0.0 2.8e-32 111.3 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP DHFR_1 PF00186.19 KIY64826.1 - 1.9e-31 108.9 0.0 2.6e-31 108.5 0.0 1.3 1 0 0 1 1 1 1 Dihydrofolate reductase NCA2 PF08637.10 KIY64827.1 - 2.9e-78 263.0 0.1 8e-78 261.5 0.1 1.5 1 1 0 1 1 1 1 ATP synthase regulation protein NCA2 DHFR_1 PF00186.19 KIY64829.1 - 7e-05 22.6 0.0 0.0001 22.1 0.0 1.4 1 1 0 1 1 1 1 Dihydrofolate reductase Bud13 PF09736.9 KIY64830.1 - 2.7e-50 170.5 13.5 2.7e-50 170.5 13.5 2.2 2 0 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex NmrA PF05368.13 KIY64831.1 - 5.8e-17 62.0 1.0 7.7e-17 61.6 1.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KIY64831.1 - 3.5e-09 36.8 0.7 3.5e-09 36.8 0.7 2.0 2 1 0 2 2 2 1 NAD(P)H-binding TrkA_N PF02254.18 KIY64831.1 - 0.00047 20.4 0.3 0.0017 18.6 0.2 1.9 1 1 1 2 2 2 1 TrkA-N domain Sacchrp_dh_NADP PF03435.18 KIY64831.1 - 0.00053 20.2 1.6 0.0011 19.2 0.5 1.9 2 1 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_2 PF03446.15 KIY64831.1 - 0.0008 19.6 0.0 0.0016 18.7 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 KIY64831.1 - 0.0012 18.7 0.4 0.0026 17.7 0.4 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KIY64831.1 - 0.0014 18.7 0.2 0.0057 16.7 0.0 1.9 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.21 KIY64831.1 - 0.0017 17.9 0.1 0.0025 17.3 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 KIY64831.1 - 0.0044 17.6 0.5 0.034 14.7 0.0 2.5 2 2 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.12 KIY64831.1 - 0.017 14.7 0.1 0.2 11.2 0.1 2.3 1 1 1 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain KR PF08659.10 KIY64831.1 - 0.046 13.6 0.2 0.12 12.3 0.2 1.7 1 1 0 1 1 1 0 KR domain ApbA PF02558.16 KIY64831.1 - 0.06 13.0 0.4 0.28 10.8 0.1 2.2 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA ADH_zinc_N PF00107.26 KIY64831.1 - 0.074 13.0 1.5 0.18 11.8 0.3 2.2 3 0 0 3 3 3 0 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KIY64831.1 - 0.12 11.7 0.0 0.37 10.1 0.0 1.9 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 KIY64831.1 - 0.14 12.2 0.5 0.27 11.3 0.1 1.6 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_7 PF13241.6 KIY64831.1 - 0.17 12.3 0.3 0.17 12.3 0.3 1.7 2 0 0 2 2 1 0 Putative NAD(P)-binding NMO PF03060.15 KIY64832.1 - 7.3e-35 120.9 1.2 1.9e-33 116.3 1.2 2.1 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KIY64832.1 - 3e-07 29.8 0.3 1.9e-05 23.9 0.0 1.9 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KIY64832.1 - 0.00035 19.7 0.5 0.00059 19.0 0.5 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KIY64832.1 - 0.00067 18.9 2.3 0.0047 16.1 2.3 1.9 1 1 0 1 1 1 1 Conserved region in glutamate synthase ADH_zinc_N PF00107.26 KIY64833.1 - 3.1e-16 59.5 0.1 1.5e-15 57.3 0.1 2.0 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIY64833.1 - 7e-10 38.8 0.1 3.4e-08 33.3 0.1 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 KIY64833.1 - 8.7e-06 25.2 0.2 1.3e-05 24.6 0.2 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KIY64833.1 - 0.0092 15.4 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Met_10 PF02475.16 KIY64833.1 - 0.0094 15.7 0.1 0.018 14.8 0.1 1.4 1 0 0 1 1 1 1 Met-10+ like-protein CoA_binding PF02629.19 KIY64833.1 - 0.021 15.5 0.0 0.088 13.5 0.0 2.0 2 0 0 2 2 2 0 CoA binding domain Methyltransf_11 PF08241.12 KIY64833.1 - 0.032 14.9 0.0 0.068 13.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Cyt-b5 PF00173.28 KIY64834.1 - 6.1e-20 71.2 0.0 9.2e-20 70.6 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain ECH_1 PF00378.20 KIY64835.1 - 1.3e-31 109.8 0.0 1.6e-31 109.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KIY64835.1 - 3.6e-14 53.0 0.0 1.5e-12 47.7 0.0 1.9 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase PTS_2-RNA PF01885.16 KIY64838.1 - 2.4e-61 206.9 0.0 2.8e-61 206.7 0.0 1.0 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family Sugar_tr PF00083.24 KIY64839.1 - 1.4e-114 383.4 27.2 1.6e-114 383.2 27.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY64839.1 - 3e-22 79.1 34.5 3e-22 79.1 34.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily RAI1 PF08652.11 KIY64841.1 - 2.3e-22 78.9 0.0 3.9e-22 78.2 0.0 1.4 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease RMI1_C PF16099.5 KIY64841.1 - 0.02 14.7 0.0 0.21 11.4 0.0 2.3 3 0 0 3 3 3 0 Recq-mediated genome instability protein 1, C-terminal OB-fold GREB1 PF15782.5 KIY64842.1 - 4.8 4.2 10.3 5.2 4.1 10.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer MDM10 PF12519.8 KIY64842.1 - 5.5 5.7 6.0 7 5.4 6.0 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Borrelia_P83 PF05262.11 KIY64842.1 - 5.6 5.3 20.6 7.1 5.0 20.6 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein SLC12 PF03522.15 KIY64842.1 - 6.3 5.7 10.1 8.4 5.3 10.1 1.1 1 0 0 1 1 1 0 Solute carrier family 12 MauJ PF17419.2 KIY64843.1 - 0.094 12.2 6.2 0.028 13.9 3.0 1.6 1 1 1 2 2 2 0 Methylamine utilization protein MauJ Herpes_UL17 PF04559.12 KIY64843.1 - 0.2 10.4 9.8 0.31 9.8 9.8 1.3 1 0 0 1 1 1 0 Herpesvirus UL17 protein TssR PF17643.1 KIY64843.1 - 2 6.2 6.6 0.33 8.8 1.3 1.9 1 1 1 2 2 2 0 Type VI secretion system, TssR Uso1_p115_C PF04871.13 KIY64843.1 - 2.1 8.7 37.1 0.72 10.2 7.9 2.7 2 1 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Fib_alpha PF08702.10 KIY64843.1 - 3.5 7.8 19.8 0.9 9.7 6.5 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Peptidase_Prp PF04327.12 KIY64844.1 - 0.039 14.2 0.1 0.074 13.3 0.1 1.4 1 0 0 1 1 1 0 Cysteine protease Prp Sacchrp_dh_C PF16653.5 KIY64845.1 - 5.1e-72 243.2 0.0 7.3e-72 242.7 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 KIY64845.1 - 7e-17 61.9 0.0 1.3e-16 61.0 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain AlaDh_PNT_N PF05222.15 KIY64845.1 - 2.2e-16 60.4 0.0 6.3e-16 58.9 0.0 1.8 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 KIY64845.1 - 2.3e-07 30.4 0.0 0.00013 21.3 0.0 2.4 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 KIY64845.1 - 0.022 15.2 0.0 0.088 13.2 0.0 2.0 2 0 0 2 2 2 0 Putative NAD(P)-binding Shikimate_DH PF01488.20 KIY64845.1 - 0.025 14.6 0.0 0.06 13.4 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GFO_IDH_MocA PF01408.22 KIY64845.1 - 0.027 15.3 0.0 0.079 13.8 0.0 1.8 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.24 KIY64845.1 - 0.053 14.0 0.0 0.18 12.3 0.0 1.9 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_3 PF03447.16 KIY64845.1 - 0.056 14.1 0.1 0.2 12.3 0.1 2.0 2 0 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain Methyltransf_15 PF09445.10 KIY64846.1 - 1.3e-37 128.9 0.0 3.8e-28 98.1 0.0 2.1 2 0 0 2 2 2 2 RNA cap guanine-N2 methyltransferase Methyltransf_25 PF13649.6 KIY64846.1 - 1.1e-07 32.4 0.0 2.1e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIY64846.1 - 1.1e-05 25.3 0.0 1.7e-05 24.7 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 KIY64846.1 - 2.6e-05 24.0 0.0 4.2e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Met_10 PF02475.16 KIY64846.1 - 3.7e-05 23.6 0.0 9.6e-05 22.2 0.0 1.6 2 0 0 2 2 2 1 Met-10+ like-protein Methyltransf_11 PF08241.12 KIY64846.1 - 7.4e-05 23.3 0.0 0.00013 22.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 KIY64846.1 - 0.0018 18.0 0.1 0.016 14.9 0.1 2.1 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_18 PF12847.7 KIY64846.1 - 0.0052 16.7 0.0 0.0093 15.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.11 KIY64846.1 - 0.015 14.3 0.0 0.021 13.8 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase PrmA PF06325.13 KIY64846.1 - 0.029 13.7 0.0 0.052 12.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KIY64846.1 - 0.033 13.8 0.0 0.055 13.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain DNA_pol3_theta PF06440.11 KIY64846.1 - 0.052 13.2 0.0 0.12 12.0 0.0 1.7 1 0 0 1 1 1 0 DNA polymerase III, theta subunit Methyltr_RsmB-F PF01189.17 KIY64846.1 - 0.053 13.2 0.0 0.08 12.6 0.0 1.2 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F SAM_MT PF04445.13 KIY64846.1 - 0.13 11.7 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase Med22 PF06179.12 KIY64847.1 - 1.3e-15 57.5 4.0 1.3e-15 57.5 4.0 1.5 1 1 1 2 2 2 1 Surfeit locus protein 5 subunit 22 of Mediator complex GATA PF00320.27 KIY64848.1 - 3.7e-15 55.2 3.6 7.2e-15 54.3 3.6 1.5 1 0 0 1 1 1 1 GATA zinc finger Bromodomain PF00439.25 KIY64849.1 - 5.1e-21 74.5 0.0 1.1e-20 73.4 0.0 1.6 1 0 0 1 1 1 1 Bromodomain Actin PF00022.19 KIY64850.1 - 2.1e-38 132.0 0.0 1.5e-36 125.9 0.0 3.0 1 1 0 1 1 1 1 Actin Glyco_hydro_3_C PF01915.22 KIY64851.1 - 4.9e-54 183.4 0.9 8.4e-54 182.6 0.1 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KIY64851.1 - 1.2e-43 149.7 0.0 2.3e-43 148.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KIY64851.1 - 7.8e-19 67.6 0.0 2.2e-18 66.1 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III-like domain Pro_isomerase PF00160.21 KIY64853.1 - 1.7e-44 151.9 0.1 2e-44 151.6 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF4716 PF15837.5 KIY64853.1 - 0.021 14.9 0.5 0.042 13.9 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4716) HSP20 PF00011.21 KIY64854.1 - 2.3e-05 24.4 0.0 0.00038 20.6 0.0 2.0 1 1 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KIY64854.1 - 0.0059 16.2 0.0 0.018 14.6 0.0 2.0 1 1 0 1 1 1 1 HSP20-like domain found in ArsA adh_short_C2 PF13561.6 KIY64855.1 - 2.6e-37 128.6 4.0 1.7e-36 125.9 4.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIY64855.1 - 1.6e-35 122.4 2.0 1.7e-35 122.3 0.8 1.7 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KIY64855.1 - 8e-07 29.1 0.5 8e-07 29.1 0.5 1.9 3 0 0 3 3 3 1 KR domain Pyr_redox PF00070.27 KIY64855.1 - 0.16 12.6 1.5 0.29 11.7 0.6 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase F-box-like PF12937.7 KIY64856.1 - 6.1e-06 26.0 4.2 6.1e-06 26.0 4.2 2.4 2 1 0 2 2 2 1 F-box-like DUF2312 PF10073.9 KIY64856.1 - 0.014 15.0 1.2 0.28 10.8 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) Prefoldin_2 PF01920.20 KIY64856.1 - 0.1 12.6 0.1 0.17 11.8 0.1 1.3 1 0 0 1 1 1 0 Prefoldin subunit F-box PF00646.33 KIY64856.1 - 1.7 8.6 6.9 6.9 6.7 1.0 3.5 3 0 0 3 3 3 0 F-box domain DUF3302 PF11742.8 KIY64857.1 - 0.0084 16.2 0.0 0.013 15.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3302) MFS_1 PF07690.16 KIY64858.1 - 4.2e-13 49.0 25.1 4.2e-13 49.0 25.1 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 KIY64858.1 - 9.7e-07 28.6 2.5 9.7e-07 28.6 2.5 2.6 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 F-box-like PF12937.7 KIY64859.1 - 3.9e-08 33.1 2.0 1.5e-07 31.2 1.7 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIY64859.1 - 0.008 16.0 1.1 5.8 6.9 0.0 2.7 2 0 0 2 2 2 2 F-box domain BCDHK_Adom3 PF10436.9 KIY64859.1 - 0.14 12.0 0.0 2.1 8.2 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase SH3_9 PF14604.6 KIY64860.1 - 2e-20 72.3 8.5 2.2e-10 40.2 1.8 2.9 2 1 0 2 2 2 2 Variant SH3 domain Cofilin_ADF PF00241.20 KIY64860.1 - 4.7e-20 71.6 0.0 8.4e-20 70.8 0.0 1.4 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SH3_1 PF00018.28 KIY64860.1 - 1e-17 63.4 8.4 2.4e-08 33.4 1.5 3.0 2 1 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 KIY64860.1 - 4.9e-12 45.3 2.6 3.6e-05 23.3 0.2 2.7 2 1 0 2 2 2 2 Variant SH3 domain F-box-like PF12937.7 KIY64861.1 - 3.6e-06 26.8 2.3 3.6e-06 26.8 2.3 2.0 2 1 0 2 2 2 1 F-box-like F-box PF00646.33 KIY64861.1 - 0.16 11.9 3.5 4 7.4 1.7 2.6 2 0 0 2 2 2 0 F-box domain MFS_1 PF07690.16 KIY64862.1 - 2.6e-36 125.3 60.0 4.3e-27 95.0 21.2 3.3 1 1 2 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 KIY64862.1 - 0.00083 18.3 10.9 0.00083 18.3 10.9 3.4 3 1 0 3 3 3 1 Sugar (and other) transporter Hva1_TUDOR PF11160.8 KIY64862.1 - 0.21 11.8 1.2 0.4 10.9 1.2 1.4 1 0 0 1 1 1 0 Hypervirulence associated proteins TUDOR domain DUF3817 PF12823.7 KIY64862.1 - 0.93 10.3 7.6 0.057 14.2 1.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3817) DUF2534 PF10749.9 KIY64862.1 - 4.5 7.5 7.2 1.8 8.8 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2534) DUF4044 PF13253.6 KIY64862.1 - 4.9 6.8 8.3 8.8 5.9 1.7 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4044) F-box-like PF12937.7 KIY64863.1 - 4.7e-09 36.0 0.9 5.3e-07 29.4 0.3 2.7 2 0 0 2 2 2 2 F-box-like F-box PF00646.33 KIY64863.1 - 0.002 18.0 3.6 0.61 10.0 0.2 3.4 3 0 0 3 3 3 2 F-box domain TetR_C_33 PF13305.6 KIY64863.1 - 0.13 13.0 0.0 0.29 11.9 0.0 1.6 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain SGL PF08450.12 KIY64864.1 - 0.00021 21.0 0.0 0.00038 20.1 0.0 1.4 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region CHZ PF09649.10 KIY64865.1 - 1.3e-12 46.9 0.9 4.1e-12 45.4 0.9 1.9 1 0 0 1 1 1 1 Histone chaperone domain CHZ Myc_N PF01056.18 KIY64865.1 - 0.00085 19.3 8.2 0.00085 19.3 8.2 1.3 1 1 0 1 1 1 1 Myc amino-terminal region DNA_pol_phi PF04931.13 KIY64865.1 - 0.013 13.6 23.0 0.014 13.5 23.0 1.0 1 0 0 1 1 1 0 DNA polymerase phi Prok-TraM PF09228.10 KIY64865.1 - 0.016 15.6 0.5 0.023 15.1 0.5 1.3 1 0 0 1 1 1 0 Prokaryotic Transcriptional repressor TraM DUF5534 PF17686.1 KIY64865.1 - 0.42 10.8 2.3 0.59 10.4 2.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5534) ANAPC15 PF15243.6 KIY64865.1 - 1.7 9.1 19.0 0.37 11.2 11.3 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 DUF2457 PF10446.9 KIY64865.1 - 2.1 7.4 19.3 2.6 7.1 19.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) BUD22 PF09073.10 KIY64865.1 - 6 6.1 23.8 6.5 6.0 23.8 1.0 1 0 0 1 1 1 0 BUD22 Autophagy_N PF03986.13 KIY64869.1 - 3e-42 143.8 0.3 6.4e-42 142.7 0.0 1.7 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.15 KIY64869.1 - 8.4e-17 61.5 0.2 1.6e-16 60.6 0.2 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 KIY64869.1 - 1.1e-12 47.2 2.9 2.2e-12 46.2 2.9 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Pterin_4a PF01329.19 KIY64870.1 - 7.8e-07 29.2 1.3 2.1e-06 27.8 1.3 1.8 1 1 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase BNR_4 PF15892.5 KIY64872.1 - 0.053 12.9 0.0 0.055 12.8 0.0 1.1 1 0 0 1 1 1 0 BNR repeat-containing family member TPR_10 PF13374.6 KIY64874.1 - 3e-07 30.1 10.1 0.85 9.6 0.0 5.7 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 KIY64874.1 - 5.9e-06 25.9 1.2 8 6.8 0.1 4.9 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 KIY64874.1 - 8.6e-06 26.2 5.1 0.67 10.9 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 KIY64874.1 - 1.4e-05 25.7 6.9 8.3 7.2 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat PSP PF04046.16 KIY64874.1 - 1.4e-05 24.8 0.0 0.57 10.1 0.0 4.3 4 0 0 4 4 4 1 PSP TPR_11 PF13414.6 KIY64874.1 - 4.3e-05 23.1 3.5 2.5 7.9 0.1 5.4 5 2 0 5 5 5 2 TPR repeat DUF3675 PF12428.8 KIY64874.1 - 5.2e-05 23.8 0.7 0.66 10.6 0.0 3.1 2 1 1 3 3 3 2 Protein of unknown function (DUF3675) TPR_2 PF07719.17 KIY64874.1 - 0.00013 21.8 0.8 8.2 6.8 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat DUF3280 PF11684.8 KIY64874.1 - 0.00044 20.7 0.0 1.1 9.7 0.0 3.6 2 1 2 4 4 4 1 Protein of unknown function (DUF2380) TPR_12 PF13424.6 KIY64874.1 - 0.0045 17.3 19.2 0.15 12.4 1.3 5.4 3 2 1 5 5 5 2 Tetratricopeptide repeat SOAR PF16533.5 KIY64874.1 - 0.023 14.6 0.0 8.9 6.4 0.0 3.0 1 1 2 3 3 3 0 STIM1 Orai1-activating region DUF3209 PF11483.8 KIY64874.1 - 0.097 13.1 1.9 17 5.9 0.1 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3209) TPR_19 PF14559.6 KIY64874.1 - 4.8 7.8 9.9 37 4.9 0.4 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat AAA_16 PF13191.6 KIY64875.1 - 8.2e-11 42.6 0.2 5.3e-10 39.9 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 KIY64875.1 - 2.3e-08 34.1 0.2 2.5e-07 30.7 0.0 2.5 2 1 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 KIY64875.1 - 0.0001 22.6 0.0 0.00035 20.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 KIY64875.1 - 0.00066 20.2 0.0 0.018 15.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KIY64875.1 - 0.028 14.8 0.0 0.08 13.3 0.0 1.8 1 0 0 1 1 1 0 RNA helicase NTPase_1 PF03266.15 KIY64875.1 - 0.047 13.6 0.0 0.083 12.8 0.0 1.5 1 0 0 1 1 1 0 NTPase AAA PF00004.29 KIY64875.1 - 0.049 14.1 0.4 0.37 11.2 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 KIY64875.1 - 0.049 13.4 0.1 0.29 10.9 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain Fib_alpha PF08702.10 KIY64875.1 - 0.1 12.8 3.1 0.15 12.3 2.3 1.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family CHORD PF04968.12 KIY64878.1 - 1.3e-45 153.9 12.5 2.1e-22 79.6 5.0 2.3 2 0 0 2 2 2 2 CHORD CS PF04969.16 KIY64878.1 - 1.1e-12 48.8 0.2 2e-12 48.0 0.2 1.4 1 0 0 1 1 1 1 CS domain An_peroxidase PF03098.15 KIY64878.1 - 0.1 11.1 0.1 0.14 10.7 0.1 1.1 1 0 0 1 1 1 0 Animal haem peroxidase BTK PF00779.19 KIY64878.1 - 0.36 10.7 12.5 2.2 8.1 0.2 4.0 4 1 0 4 4 4 0 BTK motif DNA_pol3_delta PF06144.13 KIY64879.1 - 0.11 12.3 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase III, delta subunit Fic PF02661.18 KIY64880.1 - 7.5e-12 46.0 0.0 1.1e-11 45.4 0.0 1.3 1 0 0 1 1 1 1 Fic/DOC family Peptidase_M36 PF02128.15 KIY64881.1 - 6.2e-137 456.7 3.8 8.7e-137 456.2 3.8 1.2 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) Peptidase_M4_C PF02868.15 KIY64881.1 - 2.1e-06 27.7 0.1 5.7e-06 26.3 0.1 1.7 1 0 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain FTP PF07504.13 KIY64881.1 - 0.0074 16.1 1.0 0.017 15.0 1.0 1.6 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif Fungal_trans PF04082.18 KIY64882.1 - 1.5e-27 96.3 0.0 2.6e-27 95.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY64882.1 - 1.2e-09 38.1 8.8 2.2e-09 37.3 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Exop_C PF18559.1 KIY64882.1 - 0.13 12.1 0.0 0.32 10.9 0.0 1.6 2 0 0 2 2 2 0 Galactose-binding domain-like GTP_EFTU PF00009.27 KIY64883.1 - 2.6e-34 118.5 1.2 1.3e-32 113.0 1.2 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 KIY64883.1 - 1.5e-27 95.7 0.1 5.3e-27 94.0 0.1 1.9 1 0 0 1 1 1 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 KIY64883.1 - 5e-09 36.2 0.1 1.5e-08 34.7 0.1 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 KIY64883.1 - 9.8e-05 21.9 0.0 0.0002 20.9 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KIY64883.1 - 0.0022 17.4 0.0 0.0051 16.3 0.0 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 KIY64883.1 - 0.021 14.4 0.0 0.047 13.3 0.0 1.6 1 0 0 1 1 1 0 Ras family GTP_EFTU_D2 PF03144.25 KIY64883.1 - 0.033 14.6 2.3 14 6.1 0.2 3.9 4 0 0 4 4 4 0 Elongation factor Tu domain 2 PduV-EutP PF10662.9 KIY64883.1 - 0.045 13.5 1.8 0.17 11.7 0.3 2.4 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 KIY64883.1 - 0.046 13.3 0.1 0.12 11.9 0.1 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B ALIX_LYPXL_bnd PF13949.6 KIY64883.1 - 0.051 12.9 0.7 0.094 12.0 0.7 1.3 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV Roc PF08477.13 KIY64883.1 - 0.071 13.3 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Mito_carr PF00153.27 KIY64884.1 - 5.3e-10 39.1 0.0 0.0083 16.0 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.19 KIY64884.1 - 1.3 9.5 7.1 5.7 7.4 4.9 3.0 1 1 2 3 3 3 0 Tim17/Tim22/Tim23/Pmp24 family S1 PF00575.23 KIY64885.1 - 0.11 12.8 0.0 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 S1 RNA binding domain WD40 PF00400.32 KIY64887.1 - 0.003 18.3 2.0 7 7.7 0.0 3.8 3 0 0 3 3 3 2 WD domain, G-beta repeat DUF3575 PF12099.8 KIY64887.1 - 0.028 13.7 0.0 0.065 12.5 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3575) PALB2_WD40 PF16756.5 KIY64887.1 - 0.061 12.2 0.4 0.094 11.6 0.0 1.5 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain GATase_2 PF00310.21 KIY64888.1 - 5.8e-178 591.9 0.0 8.6e-178 591.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 KIY64888.1 - 5.8e-155 516.0 0.0 1.1e-154 515.0 0.0 1.5 1 0 0 1 1 1 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 KIY64888.1 - 1.8e-112 375.4 0.0 1.6e-110 369.0 0.0 2.2 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 KIY64888.1 - 5.8e-86 287.0 3.5 9.9e-86 286.2 3.5 1.4 1 0 0 1 1 1 1 GXGXG motif Pyr_redox_2 PF07992.14 KIY64888.1 - 3.4e-25 88.9 0.0 1.5e-24 86.7 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 KIY64888.1 - 6.8e-22 77.4 0.1 1.3e-21 76.5 0.1 1.5 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster NAD_binding_8 PF13450.6 KIY64888.1 - 4e-09 36.6 0.0 1.4e-08 34.8 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KIY64888.1 - 4.2e-08 32.8 0.6 0.0011 18.3 0.0 3.5 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIY64888.1 - 9.3e-08 32.5 0.1 0.0001 22.8 0.0 3.7 3 1 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIY64888.1 - 2.2e-07 30.8 0.2 0.00078 19.1 0.1 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 KIY64888.1 - 2.7e-06 26.3 0.1 2.7e-06 26.3 0.1 1.8 2 0 0 2 2 2 1 HI0933-like protein Amino_oxidase PF01593.24 KIY64888.1 - 6.1e-05 22.5 0.0 0.0001 21.7 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FMN_dh PF01070.18 KIY64888.1 - 0.00025 20.2 0.8 0.011 14.8 1.1 2.8 3 0 0 3 3 3 1 FMN-dependent dehydrogenase FAD_binding_2 PF00890.24 KIY64888.1 - 0.0012 18.0 0.0 0.0012 18.0 0.0 3.0 4 0 0 4 4 3 1 FAD binding domain FAD_oxidored PF12831.7 KIY64888.1 - 0.0018 17.7 0.1 0.0018 17.7 0.1 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KIY64888.1 - 0.0037 16.5 0.6 0.012 14.9 0.0 2.0 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 KIY64888.1 - 0.0042 16.4 0.0 0.0089 15.3 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 KIY64888.1 - 0.0048 16.2 0.1 0.44 9.8 0.0 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 KIY64888.1 - 0.0069 16.8 0.4 1.6 9.2 0.0 2.7 2 0 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_2 PF03446.15 KIY64888.1 - 0.017 15.3 0.1 0.053 13.7 0.1 1.9 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_9 PF13454.6 KIY64888.1 - 0.024 14.7 0.1 0.083 12.9 0.0 2.0 2 0 0 2 2 1 0 FAD-NAD(P)-binding ApbA PF02558.16 KIY64888.1 - 0.026 14.2 0.3 0.055 13.1 0.3 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.12 KIY64888.1 - 0.033 13.2 0.2 0.097 11.7 0.1 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein 3HCDH_N PF02737.18 KIY64888.1 - 0.037 13.9 0.1 0.088 12.7 0.1 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KIY64888.1 - 0.037 13.4 0.0 0.19 11.1 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 KIY64888.1 - 0.082 12.9 0.0 0.21 11.5 0.0 1.7 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FMO-like PF00743.19 KIY64888.1 - 0.09 11.2 0.0 2.9 6.2 0.0 2.8 3 0 0 3 3 3 0 Flavin-binding monooxygenase-like UDPG_MGDP_dh_N PF03721.14 KIY64888.1 - 0.097 12.2 0.1 0.19 11.3 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GATase_6 PF13522.6 KIY64888.1 - 0.12 12.6 0.1 0.36 11.0 0.1 1.8 1 0 0 1 1 1 0 Glutamine amidotransferase domain F420_oxidored PF03807.17 KIY64888.1 - 0.17 12.5 1.0 0.46 11.1 0.1 2.2 2 0 0 2 2 1 0 NADP oxidoreductase coenzyme F420-dependent AdoHcyase_NAD PF00670.21 KIY64888.1 - 0.23 11.5 2.5 20 5.2 0.1 3.3 3 0 0 3 3 3 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain GIDA PF01134.22 KIY64888.1 - 0.57 9.2 7.4 0.067 12.3 0.1 2.8 3 0 0 3 3 3 0 Glucose inhibited division protein A Glyco_hydro_cc PF11790.8 KIY64890.1 - 2.9e-41 141.6 0.5 3.4e-41 141.4 0.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Glyco_hydro_30 PF02055.16 KIY64890.1 - 0.016 14.2 0.0 0.022 13.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 30 TIM-barrel domain F-box-like PF12937.7 KIY64891.1 - 1.2e-09 37.9 0.4 2.3e-09 37.0 0.4 1.5 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KIY64891.1 - 0.14 12.1 1.3 3.1 7.8 0.6 2.2 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.7 KIY64892.1 - 0.0003 20.6 0.3 0.00093 19.0 0.3 1.8 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KIY64893.1 - 4.1e-05 23.4 1.3 0.00014 21.7 1.3 1.9 1 0 0 1 1 1 1 F-box-like Acetyltransf_13 PF13880.6 KIY64894.1 - 2e-16 59.7 0.0 3.5e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.6 KIY64894.1 - 3e-07 30.1 0.4 5e-07 29.4 0.4 1.4 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_7 PF13508.7 KIY64894.1 - 0.0016 18.8 0.0 0.0041 17.5 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KIY64894.1 - 0.024 14.6 0.0 0.04 13.9 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIY64894.1 - 0.041 14.1 0.0 0.07 13.4 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Zn-C2H2_12 PF18112.1 KIY64894.1 - 0.083 13.4 0.1 0.14 12.6 0.1 1.4 1 0 0 1 1 1 0 Autophagy receptor zinc finger-C2H2 domain Cadherin_C_2 PF16492.5 KIY64895.1 - 0.061 14.1 1.7 0.13 13.0 1.7 1.5 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal DUF2156 PF09924.9 KIY64897.1 - 5.3e-15 55.2 0.0 1.4e-14 53.8 0.0 1.6 1 1 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) Abhydrolase_3 PF07859.13 KIY64898.1 - 7.4e-24 84.8 0.1 3.7e-19 69.4 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KIY64898.1 - 1.5e-09 37.2 0.0 2.8e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Steryl acetyl hydrolase Hydrolase_4 PF12146.8 KIY64898.1 - 0.00038 19.8 0.0 0.00077 18.8 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thg1 PF04446.12 KIY64899.1 - 1.2e-47 161.0 0.0 2e-47 160.3 0.0 1.4 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.6 KIY64899.1 - 1.9e-43 147.5 4.8 9.9e-43 145.2 4.8 1.9 1 1 0 1 1 1 1 Thg1 C terminal domain HMG_box PF00505.19 KIY64901.1 - 1.7e-17 63.5 1.1 1.9e-17 63.4 1.1 1.0 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KIY64901.1 - 3.5e-08 33.9 0.7 3.9e-08 33.8 0.7 1.0 1 0 0 1 1 1 1 HMG-box domain Adaptin_N PF01602.20 KIY64902.1 - 1.5e-93 314.2 6.5 2.1e-93 313.7 6.5 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.6 KIY64902.1 - 3.1e-58 195.3 0.0 7.5e-58 194.1 0.0 1.7 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.12 KIY64902.1 - 9.2e-54 181.2 0.0 2.3e-53 179.9 0.0 1.8 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT_2 PF13646.6 KIY64902.1 - 3.4e-11 43.4 1.3 0.0078 16.6 0.0 5.9 1 1 4 6 6 6 4 HEAT repeats HEAT PF02985.22 KIY64902.1 - 3.8e-08 32.9 0.1 0.19 12.1 0.0 5.7 5 0 0 5 5 4 1 HEAT repeat Cnd1 PF12717.7 KIY64902.1 - 4.1e-08 33.4 7.0 8.6e-05 22.6 0.1 3.7 1 1 2 3 3 3 3 non-SMC mitotic condensation complex subunit 1 DUF5578 PF17741.1 KIY64902.1 - 7e-06 25.7 4.9 0.045 13.2 1.1 3.2 1 1 2 3 3 3 2 Family of unknown function (DUF5578) RTP1_C1 PF10363.9 KIY64902.1 - 2e-05 24.7 2.0 0.073 13.3 0.0 3.4 3 0 0 3 3 3 2 Required for nuclear transport of RNA pol II C-terminus 1 DUF5071 PF16804.5 KIY64902.1 - 0.004 17.4 1.7 0.2 11.9 0.0 3.7 1 1 2 4 4 4 1 Domain of unknown function (DUF5071) DNA_alkylation PF08713.11 KIY64902.1 - 0.041 13.6 0.2 1.7 8.3 0.0 2.9 3 0 0 3 3 3 0 DNA alkylation repair enzyme ParcG PF10274.9 KIY64902.1 - 0.041 14.0 1.9 4.4 7.4 0.0 2.9 3 0 0 3 3 3 0 Parkin co-regulated protein Gemini_V2 PF01524.17 KIY64902.1 - 0.16 12.2 0.0 2.5 8.4 0.0 2.7 2 0 0 2 2 2 0 Geminivirus V2 protein Meis_PKNOX_N PF16493.5 KIY64902.1 - 0.17 12.2 0.7 1.1 9.7 0.2 2.7 2 0 0 2 2 1 0 N-terminal of Homeobox Meis and PKNOX1 RasGEF_N_2 PF14663.6 KIY64902.1 - 0.41 11.1 2.1 35 4.9 0.1 3.9 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain R3H PF01424.22 KIY64904.1 - 1.1e-09 38.2 0.1 2.1e-09 37.2 0.1 1.5 1 0 0 1 1 1 1 R3H domain RRM_1 PF00076.22 KIY64904.1 - 6.6e-07 29.1 0.0 1.5e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UQ_con PF00179.26 KIY64906.1 - 2.6e-43 147.0 0.0 3e-43 146.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KIY64906.1 - 0.00034 20.9 0.0 0.00038 20.7 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.13 KIY64906.1 - 0.055 13.3 0.0 0.081 12.8 0.0 1.3 1 1 0 1 1 1 0 UEV domain EF-hand_4 PF12763.7 KIY64907.1 - 2.7e-30 104.4 0.0 1.2e-13 50.9 0.0 3.4 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand UBA PF00627.31 KIY64907.1 - 4e-07 29.8 0.1 8e-07 28.8 0.1 1.5 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_7 PF13499.6 KIY64907.1 - 0.0015 18.9 0.0 0.23 11.9 0.0 3.4 3 0 0 3 3 3 1 EF-hand domain pair DUF1720 PF08226.11 KIY64907.1 - 0.0034 17.7 20.4 0.0034 17.7 20.4 6.5 6 1 0 6 6 5 1 Domain of unknown function (DUF1720) UBA_3 PF09288.10 KIY64907.1 - 0.015 15.1 0.4 0.12 12.2 0.0 2.5 3 0 0 3 3 3 0 Fungal ubiquitin-associated domain HBS1_N PF08938.10 KIY64907.1 - 0.075 13.3 0.6 0.18 12.1 0.0 2.0 2 0 0 2 2 1 0 HBS1 N-terminus CENP-F_leu_zip PF10473.9 KIY64907.1 - 1.7 8.7 23.7 5.4 7.0 23.5 1.9 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 EMC3_TMCO1 PF01956.16 KIY64907.1 - 2.1 8.1 4.3 5.1 6.8 4.3 1.6 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Synaptobrevin PF00957.21 KIY64907.1 - 3.4 7.5 4.2 7.7 6.4 4.2 1.6 1 0 0 1 1 1 0 Synaptobrevin Exonuc_VII_L PF02601.15 KIY64907.1 - 4.5 6.7 18.4 7.7 6.0 18.4 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Spc7 PF08317.11 KIY64907.1 - 6.4 5.6 30.3 2.4 7.0 8.5 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein V_ATPase_I PF01496.19 KIY64907.1 - 8 4.2 12.0 13 3.5 12.0 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Autophagy_act_C PF03987.15 KIY64909.1 - 0.089 13.4 0.1 0.24 12.0 0.0 1.8 2 0 0 2 2 2 0 Autophagocytosis associated protein, active-site domain Peptidase_S9 PF00326.21 KIY64911.1 - 3.5e-11 43.0 0.0 6.6e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KIY64911.1 - 0.0011 18.7 0.6 0.0035 17.0 0.3 2.0 1 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 KIY64911.1 - 0.0026 17.6 0.0 1.9 8.3 0.0 2.5 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 KIY64911.1 - 0.0073 15.6 0.1 0.25 10.6 0.0 2.3 1 1 0 2 2 2 1 Serine aminopeptidase, S33 3HBOH PF10605.9 KIY64911.1 - 0.0075 14.6 0.0 0.011 14.0 0.0 1.1 1 0 0 1 1 1 1 3HB-oligomer hydrolase (3HBOH) Esterase PF00756.20 KIY64911.1 - 0.021 14.4 0.5 0.04 13.6 0.5 1.4 1 0 0 1 1 1 0 Putative esterase Tannase PF07519.11 KIY64911.1 - 0.058 12.3 0.0 0.09 11.7 0.0 1.2 1 0 0 1 1 1 0 Tannase and feruloyl esterase Striatin PF08232.12 KIY64912.1 - 1.2e-50 172.2 3.9 8.4e-50 169.4 0.0 2.3 2 0 0 2 2 2 1 Striatin family WD40 PF00400.32 KIY64912.1 - 1e-38 130.6 5.5 7.9e-07 29.7 0.1 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY64912.1 - 7e-11 42.3 0.0 0.015 15.5 0.0 5.8 2 2 1 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 KIY64912.1 - 1.5e-06 27.3 0.0 0.065 12.0 0.1 3.7 2 2 2 4 4 4 2 Nup133 N terminal like Nup160 PF11715.8 KIY64912.1 - 0.0056 15.4 0.6 2.2 6.8 0.0 4.0 2 2 1 5 5 5 1 Nucleoporin Nup120/160 PQQ_2 PF13360.6 KIY64912.1 - 0.026 14.1 0.0 0.068 12.7 0.0 1.6 2 0 0 2 2 2 0 PQQ-like domain YAcAr PF10686.9 KIY64912.1 - 0.031 14.2 0.0 0.08 12.9 0.0 1.6 1 0 0 1 1 1 0 YspA, cpYpsA-related SLOG family Herpes_capsid PF06112.11 KIY64913.1 - 0.73 9.9 10.2 1.1 9.2 10.2 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein DUF4614 PF15391.6 KIY64914.1 - 1.2 9.1 12.5 1.9 8.4 12.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) PI-PLC-C1 PF16670.5 KIY64916.1 - 0.26 10.3 0.3 7 5.6 0.0 2.8 3 1 1 4 4 4 0 Phosphoinositide phospholipase C, Ca2+-dependent FAD_binding_4 PF01565.23 KIY64917.1 - 1.8e-28 99.0 4.8 3e-28 98.3 4.8 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KIY64917.1 - 3e-12 46.4 3.0 6.5e-12 45.4 3.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like OTT_1508_deam PF14441.6 KIY64919.1 - 7.6e-07 29.1 0.0 1.7e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 OTT_1508-like deaminase Hydrolase_4 PF12146.8 KIY64920.1 - 0.00024 20.4 0.0 0.0012 18.2 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KIY64920.1 - 0.00094 18.9 0.0 0.029 14.0 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Ribosomal_S21 PF01165.20 KIY64922.1 - 1.4e-11 43.9 1.4 2.3e-11 43.2 1.4 1.4 1 0 0 1 1 1 1 Ribosomal protein S21 RWD PF05773.22 KIY64923.1 - 3.2e-18 66.1 0.1 5.6e-18 65.3 0.1 1.4 1 0 0 1 1 1 1 RWD domain DFRP_C PF16543.5 KIY64923.1 - 2.3e-07 31.2 9.7 2.3e-07 31.2 9.7 2.5 1 1 1 2 2 2 1 DRG Family Regulatory Proteins, Tma46 Spc7_C2 PF15577.6 KIY64923.1 - 0.022 14.8 0.0 0.052 13.6 0.0 1.6 1 0 0 1 1 1 0 Spc7_C2 Cyclin_N PF00134.23 KIY64925.1 - 4.5e-15 55.5 1.6 3e-14 52.9 0.6 2.4 2 1 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KIY64925.1 - 0.00042 20.4 0.1 0.091 12.9 0.0 2.6 2 1 0 2 2 2 2 Cyclin, C-terminal domain TFIIB PF00382.19 KIY64925.1 - 0.00061 19.8 0.8 0.003 17.6 0.0 2.1 2 0 0 2 2 2 1 Transcription factor TFIIB repeat SHS2_FTSA PF02491.20 KIY64925.1 - 0.19 12.1 0.0 0.33 11.4 0.0 1.3 1 0 0 1 1 1 0 SHS2 domain inserted in FTSA IF-2B PF01008.17 KIY64926.1 - 4.2e-59 200.1 0.0 8.4e-59 199.1 0.0 1.4 1 1 0 1 1 1 1 Initiation factor 2 subunit family PGBA_N PF15436.6 KIY64926.1 - 0.083 12.5 0.0 9.4 5.8 0.0 2.2 2 0 0 2 2 2 0 Plasminogen-binding protein pgbA N-terminal DUF1265 PF06887.14 KIY64927.1 - 0.17 11.9 0.4 1 9.4 0.0 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1265) Peptidase_M24 PF00557.24 KIY64928.1 - 5.6e-51 173.2 0.0 7.1e-51 172.9 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 KIY64928.1 - 1.6e-18 66.8 8.7 2.8e-18 66.0 8.7 1.4 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 KIY64928.1 - 4.2e-05 23.6 4.4 9.8e-05 22.4 4.4 1.7 1 0 0 1 1 1 1 MYND finger Sugar_tr PF00083.24 KIY64929.1 - 1.2e-122 410.1 21.3 1.4e-122 409.9 21.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY64929.1 - 4.3e-21 75.2 61.3 5.1e-20 71.7 34.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Hydrophobin PF01185.18 KIY64930.1 - 3.3e-09 37.3 11.1 4e-09 37.0 11.1 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Waikav_capsid_1 PF12264.8 KIY64930.1 - 0.058 12.9 0.1 0.068 12.7 0.1 1.1 1 0 0 1 1 1 0 Waikavirus capsid protein 1 Acyltransferase PF01553.21 KIY64931.1 - 1e-11 44.6 0.0 7.5e-11 41.8 0.0 2.2 1 1 0 1 1 1 1 Acyltransferase CLASP_N PF12348.8 KIY64932.1 - 3e-24 85.8 0.0 1.4e-06 28.1 0.0 5.0 5 0 0 5 5 5 4 CLASP N terminal HEAT PF02985.22 KIY64932.1 - 3.9e-08 32.9 23.2 0.62 10.5 0.0 10.9 13 0 0 13 13 13 3 HEAT repeat HEAT_2 PF13646.6 KIY64932.1 - 9.6e-08 32.3 23.5 0.1 13.0 0.0 9.9 8 3 1 10 10 10 3 HEAT repeats Cnd1 PF12717.7 KIY64932.1 - 3.8e-07 30.3 3.6 0.37 10.8 0.1 6.7 6 2 0 6 6 6 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 KIY64932.1 - 0.012 14.2 0.6 2.9 6.3 0.0 3.9 4 0 0 4 4 4 0 Adaptin N terminal region Nipped-B_C PF12830.7 KIY64932.1 - 0.11 12.4 0.4 3.3 7.6 0.0 3.2 4 0 0 4 4 4 0 Sister chromatid cohesion C-terminus HEAT_EZ PF13513.6 KIY64932.1 - 0.28 11.7 8.8 6.1 7.5 0.0 6.7 7 2 0 7 7 7 0 HEAT-like repeat TAN PF11640.8 KIY64932.1 - 0.33 11.1 7.2 1.5 8.9 0.1 4.6 6 0 0 6 6 6 0 Telomere-length maintenance and DNA damage repair MMS19_N PF14500.6 KIY64932.1 - 2.6 7.6 6.2 64 3.0 0.1 5.4 6 2 0 7 7 7 0 Dos2-interacting transcription regulator of RNA-Pol-II OTT_1508_deam PF14441.6 KIY64933.1 - 4.6e-08 33.0 0.1 9.4e-08 32.0 0.1 1.5 1 0 0 1 1 1 1 OTT_1508-like deaminase NOC3p PF07540.11 KIY64934.1 - 2e-29 101.9 0.0 6.6e-29 100.2 0.0 2.0 1 0 0 1 1 1 1 Nucleolar complex-associated protein CBF PF03914.17 KIY64934.1 - 3.5e-18 66.2 0.0 2.6e-17 63.4 0.0 2.4 1 1 0 2 2 2 1 CBF/Mak21 family BCL_N PF04714.13 KIY64934.1 - 0.14 12.2 1.0 0.45 10.6 0.1 2.2 2 0 0 2 2 2 0 BCL7, N-terminal conserver region TEA PF01285.18 KIY64935.1 - 5.9e-16 58.3 0.1 9.2e-16 57.7 0.1 1.3 1 0 0 1 1 1 1 TEA/ATTS domain ANAPC4 PF12896.7 KIY64935.1 - 0.021 14.4 0.1 0.028 13.9 0.1 1.1 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 4 zf-C2H2_12 PF18658.1 KIY64935.1 - 0.075 12.6 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger C2H2-type UEV PF05743.13 KIY64936.1 - 2.3e-35 121.1 0.0 3.6e-35 120.5 0.0 1.3 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.10 KIY64936.1 - 7.1e-28 96.4 0.2 1.3e-27 95.5 0.2 1.4 1 0 0 1 1 1 1 Vps23 core domain UQ_con PF00179.26 KIY64936.1 - 0.11 12.1 0.0 0.26 10.9 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-conjugating enzyme THOC7 PF05615.13 KIY64936.1 - 0.19 12.0 0.1 0.42 10.9 0.1 1.5 1 0 0 1 1 1 0 Tho complex subunit 7 MSC PF09402.10 KIY64937.1 - 4.8e-68 230.1 0.0 6.2e-68 229.7 0.0 1.1 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.7 KIY64937.1 - 8.7e-11 41.3 0.0 1.6e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 HeH/LEM domain DCR PF14047.6 KIY64937.1 - 0.054 13.7 0.1 0.15 12.3 0.1 1.7 1 0 0 1 1 1 0 Dppa2/4 conserved region PC_rep PF01851.22 KIY64937.1 - 1.1 9.8 3.7 0.59 10.7 0.2 2.5 2 1 1 3 3 3 0 Proteasome/cyclosome repeat MutS_V PF00488.21 KIY64938.1 - 2.3e-56 190.8 0.0 7.3e-56 189.2 0.0 1.9 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KIY64938.1 - 2.4e-32 112.7 3.8 1.5e-31 110.1 1.7 2.3 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 KIY64938.1 - 3.2e-07 30.6 0.0 7.7e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 KIY64938.1 - 7.3e-05 23.1 0.6 0.0011 19.3 0.1 2.8 2 1 0 2 2 2 1 MutS domain II DOG1 PF14144.6 KIY64938.1 - 0.14 12.4 0.5 1.9 8.8 0.1 2.8 2 0 0 2 2 2 0 Seed dormancy control DUF935 PF06074.12 KIY64939.1 - 0.00062 18.6 0.4 0.00086 18.2 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF935) SSP160 PF06933.11 KIY64939.1 - 0.00092 17.6 11.8 0.0011 17.3 11.8 1.0 1 0 0 1 1 1 1 Special lobe-specific silk protein SSP160 Syntaxin-6_N PF09177.11 KIY64939.1 - 0.033 14.7 0.1 0.15 12.7 0.0 1.7 1 1 0 2 2 2 0 Syntaxin 6, N-terminal MGC-24 PF05283.11 KIY64939.1 - 4.6 7.7 8.0 8.2 6.9 8.0 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin MAPEG PF01124.18 KIY64941.1 - 1.4e-15 57.4 2.8 1.7e-15 57.1 2.8 1.1 1 0 0 1 1 1 1 MAPEG family Ferric_reduct PF01794.19 KIY64942.1 - 7.8e-19 68.0 10.6 7.8e-19 68.0 10.6 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KIY64942.1 - 2.6e-14 53.6 0.1 2.1e-10 40.9 0.0 3.2 3 0 0 3 3 3 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KIY64942.1 - 2.4e-09 37.2 0.0 4.3e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 FAD-binding domain Tmemb_14 PF03647.13 KIY64942.1 - 0.65 10.8 3.1 4.4 8.1 3.1 2.5 1 1 0 1 1 1 0 Transmembrane proteins 14C Ctr PF04145.15 KIY64943.1 - 1.2e-27 97.4 2.0 1.4e-27 97.1 2.0 1.0 1 0 0 1 1 1 1 Ctr copper transporter family Glyoxalase PF00903.25 KIY64944.1 - 2.3e-24 86.0 0.2 3.1e-24 85.6 0.2 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KIY64944.1 - 3.9e-06 27.1 0.0 8.9e-06 25.9 0.0 1.6 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 KIY64944.1 - 4.2e-06 27.5 0.0 5.5e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_2 PF12681.7 KIY64944.1 - 0.0047 16.8 0.1 0.33 10.9 0.1 2.2 1 1 0 1 1 1 1 Glyoxalase-like domain CppA_N PF14506.6 KIY64944.1 - 0.012 15.7 0.0 0.016 15.3 0.0 1.2 1 0 0 1 1 1 0 CppA N-terminal Glyoxalase_3 PF13468.6 KIY64944.1 - 0.014 15.5 0.0 0.032 14.3 0.0 1.7 2 0 0 2 2 2 0 Glyoxalase-like domain STE3 PF02076.15 KIY64945.1 - 2.9e-98 328.7 13.2 3.4e-98 328.4 13.2 1.1 1 0 0 1 1 1 1 Pheromone A receptor DUF973 PF06157.11 KIY64945.1 - 0.0027 16.8 0.0 0.004 16.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF973) HemY_N PF07219.13 KIY64945.1 - 0.038 14.2 0.0 0.084 13.1 0.0 1.6 1 0 0 1 1 1 0 HemY protein N-terminus PDR_assoc PF08370.11 KIY64945.1 - 0.05 13.3 0.9 0.16 11.7 0.9 1.8 1 0 0 1 1 1 0 Plant PDR ABC transporter associated PALP PF00291.25 KIY64946.1 - 4e-61 207.0 0.0 1e-59 202.4 0.0 2.0 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Myb_DNA-binding PF00249.31 KIY64947.1 - 3.8e-11 43.0 0.2 8.5e-11 41.9 0.2 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain SWIRM PF04433.17 KIY64947.1 - 4.5e-09 36.5 0.1 1.5e-08 34.9 0.0 1.9 2 1 0 2 2 2 1 SWIRM domain Myb_DNA-bind_6 PF13921.6 KIY64947.1 - 0.00022 21.4 0.0 0.00061 20.0 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.17 KIY64947.1 - 0.058 13.2 7.5 0.15 11.9 7.5 1.6 1 0 0 1 1 1 0 Zinc finger, ZZ type F-box PF00646.33 KIY64948.1 - 0.00048 19.9 0.2 0.0013 18.5 0.2 1.7 1 0 0 1 1 1 1 F-box domain JMY PF15871.5 KIY64948.1 - 0.0016 17.8 0.6 0.0025 17.2 0.6 1.3 1 0 0 1 1 1 1 Junction-mediating and -regulatory protein F-box-like PF12937.7 KIY64948.1 - 0.026 14.4 0.4 0.12 12.3 0.1 2.3 3 0 0 3 3 3 0 F-box-like zf-RING_4 PF14570.6 KIY64948.1 - 0.14 12.0 5.1 0.1 12.4 2.7 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain F-box_4 PF15966.5 KIY64948.1 - 0.27 11.2 3.3 0.42 10.5 0.0 2.9 3 0 0 3 3 3 0 F-box F-box PF00646.33 KIY64949.1 - 0.0047 16.8 2.7 0.02 14.8 0.5 2.7 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KIY64949.1 - 0.016 15.1 2.4 0.34 10.8 0.3 2.7 2 0 0 2 2 2 0 F-box-like Glyco_transf_18 PF15024.6 KIY64949.1 - 0.035 12.7 0.0 0.057 12.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 18 zf-RING_4 PF14570.6 KIY64949.1 - 0.74 9.7 7.0 3.1 7.7 7.0 2.0 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain F-box PF00646.33 KIY64951.1 - 0.0013 18.5 0.0 0.0013 18.5 0.0 2.8 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.7 KIY64951.1 - 0.0033 17.3 0.1 0.015 15.2 0.1 2.2 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KIY64951.1 - 0.095 12.6 0.0 0.3 11.0 0.0 1.9 1 0 0 1 1 1 0 F-box Con-6 PF10346.9 KIY64953.1 - 2.4e-07 30.7 0.1 2.4e-07 30.7 0.1 1.6 2 0 0 2 2 2 1 Conidiation protein 6 MTBP_mid PF14919.6 KIY64953.1 - 0.21 10.8 0.0 0.21 10.7 0.0 1.0 1 0 0 1 1 1 0 MDM2-binding O-FucT PF10250.9 KIY64954.1 - 2.8e-15 56.9 0.0 5.9e-15 55.8 0.0 1.5 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Glyco_transf_11 PF01531.16 KIY64954.1 - 0.067 12.4 0.0 0.17 11.1 0.0 1.6 2 0 0 2 2 2 0 Glycosyl transferase family 11 GST_N_2 PF13409.6 KIY64955.1 - 2.3e-08 34.2 0.0 5.1e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 KIY64955.1 - 6.9e-07 29.9 0.0 1.7e-06 28.7 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_N_3 PF13417.6 KIY64955.1 - 1.2e-06 28.9 0.0 2.3e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KIY64955.1 - 1.3e-05 25.5 0.0 3.8e-05 23.9 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KIY64955.1 - 0.00028 21.0 0.0 0.00061 19.9 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KIY64955.1 - 0.0007 19.8 0.0 0.0011 19.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 KIY64955.1 - 0.0035 17.6 0.0 0.0052 17.1 0.0 1.3 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.6 KIY64955.1 - 0.014 15.4 0.0 0.021 14.9 0.0 1.4 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain PKcGMP_CC PF16808.5 KIY64956.1 - 0.26 11.2 4.6 0.38 10.6 4.6 1.2 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Baculo_PEP_C PF04513.12 KIY64957.1 - 0.76 9.8 4.1 13 5.8 0.2 2.9 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Peptidase_S10 PF00450.22 KIY64958.1 - 5.3e-88 296.2 0.4 6.4e-88 295.9 0.4 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase V-SNARE PF05008.15 KIY64959.1 - 4.4e-20 71.9 2.2 4.4e-20 71.9 2.2 2.1 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 KIY64959.1 - 5.2e-14 52.3 3.8 5.2e-14 52.3 3.8 2.2 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 KIY64959.1 - 0.00049 20.0 0.7 0.00092 19.1 0.1 1.7 2 0 0 2 2 2 1 Sec20 Exonuc_VII_L PF02601.15 KIY64959.1 - 0.023 14.3 4.9 0.12 11.9 4.9 1.8 1 1 0 1 1 1 0 Exonuclease VII, large subunit Orf78 PF06024.12 KIY64959.1 - 0.038 14.3 0.1 0.069 13.5 0.1 1.5 1 0 0 1 1 1 0 Orf78 (ac78) Nbl1_Borealin_N PF10444.9 KIY64959.1 - 0.051 13.2 0.1 1.7 8.4 0.1 2.7 1 1 1 2 2 2 0 Nbl1 / Borealin N terminal Prominin PF05478.11 KIY64959.1 - 0.054 11.5 1.2 0.077 10.9 1.2 1.6 1 1 0 1 1 1 0 Prominin Pox_EPC_I2-L1 PF12575.8 KIY64959.1 - 0.055 13.7 0.9 0.12 12.7 0.9 1.5 1 0 0 1 1 1 0 Poxvirus entry protein complex L1 and I2 LXG PF04740.12 KIY64959.1 - 0.29 10.8 2.9 2.5 7.8 0.1 2.3 2 1 0 2 2 2 0 LXG domain of WXG superfamily MR_MLE_N PF02746.16 KIY64960.1 - 0.022 15.0 4.0 0.037 14.3 3.8 1.6 1 1 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Baculo_PEP_C PF04513.12 KIY64960.1 - 0.076 13.1 6.1 1.1 9.3 0.2 2.4 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus CHDCT2 PF08074.11 KIY64960.1 - 0.12 12.6 0.1 0.28 11.4 0.0 1.6 1 1 0 1 1 1 0 CHDCT2 (NUC038) domain FAM199X PF15814.5 KIY64960.1 - 0.27 10.3 5.0 0.4 9.7 5.0 1.3 1 0 0 1 1 1 0 Protein family FAM199X SAP130_C PF16014.5 KIY64960.1 - 1.5 7.8 9.5 1.8 7.6 9.5 1.2 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus TMF_DNA_bd PF12329.8 KIY64961.1 - 0.00057 19.8 1.8 0.00089 19.2 1.8 1.3 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding Jacalin PF01419.17 KIY64961.1 - 0.011 15.6 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 Jacalin-like lectin domain Atg14 PF10186.9 KIY64961.1 - 0.045 12.8 0.9 0.063 12.4 0.9 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FPP PF05911.11 KIY64961.1 - 0.072 11.3 2.0 0.09 10.9 2.0 1.0 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil bZIP_1 PF00170.21 KIY64961.1 - 0.072 13.2 1.0 0.13 12.4 1.0 1.4 1 0 0 1 1 1 0 bZIP transcription factor Filament PF00038.21 KIY64961.1 - 0.08 12.5 2.1 0.11 12.1 2.1 1.1 1 0 0 1 1 1 0 Intermediate filament protein YabA PF06156.13 KIY64961.1 - 0.081 13.6 1.1 0.15 12.8 1.1 1.4 1 0 0 1 1 1 0 Initiation control protein YabA ZapB PF06005.12 KIY64961.1 - 0.092 13.2 1.0 0.17 12.4 1.0 1.5 1 1 0 1 1 1 0 Cell division protein ZapB ATG16 PF08614.11 KIY64961.1 - 0.13 12.5 4.4 0.18 12.0 4.4 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF4472 PF14739.6 KIY64961.1 - 0.17 12.6 2.5 0.25 12.1 2.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) UPF0242 PF06785.11 KIY64961.1 - 0.28 11.3 2.1 0.42 10.7 2.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4618 PF15397.6 KIY64961.1 - 0.32 10.4 3.3 0.5 9.7 3.3 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) Lectin_N PF03954.14 KIY64961.1 - 3.8 7.2 6.1 13 5.6 0.5 2.1 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain FAM184 PF15665.5 KIY64962.1 - 0.00091 19.1 1.9 0.0017 18.2 0.8 1.8 1 1 1 2 2 2 1 Family with sequence similarity 184, A and B NRBF2 PF08961.10 KIY64962.1 - 0.033 13.8 0.9 0.048 13.3 0.9 1.2 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator CENP-Q PF13094.6 KIY64962.1 - 0.36 11.0 6.0 0.53 10.5 6.0 1.2 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit FA_desaturase PF00487.24 KIY64963.1 - 4.7e-25 88.9 17.9 9.8e-25 87.8 17.9 1.4 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 KIY64963.1 - 0.00016 21.9 0.0 0.00037 20.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Pkinase PF00069.25 KIY64964.1 - 5.8e-15 55.4 0.0 1.1e-14 54.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY64964.1 - 5.4e-08 32.4 0.0 1e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIY64964.1 - 1.6e-05 23.9 0.1 2.5e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KIY64964.1 - 0.064 13.2 0.0 0.55 10.1 0.0 2.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family AA_kinase PF00696.28 KIY64964.1 - 0.14 11.7 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Amino acid kinase family Fasciclin PF02469.22 KIY64965.1 - 2.9e-28 98.6 0.0 3.5e-17 62.8 0.0 3.8 2 2 0 2 2 2 2 Fasciclin domain LMSTEN PF07988.12 KIY64965.1 - 0.16 11.5 0.8 0.39 10.2 0.8 1.6 1 0 0 1 1 1 0 LMSTEN motif PhoLip_ATPase_C PF16212.5 KIY64966.1 - 4e-52 177.4 23.0 4e-52 177.4 23.0 2.6 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KIY64966.1 - 4e-17 61.7 4.2 1e-16 60.3 4.2 1.7 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KIY64966.1 - 5.8e-14 52.9 0.7 4.5e-11 43.4 0.7 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KIY64966.1 - 2.1e-13 50.2 0.0 2.1e-13 50.2 0.0 2.5 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 KIY64966.1 - 3.6e-08 33.4 0.0 3.8e-07 30.1 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KIY64966.1 - 0.0013 18.6 0.0 0.0025 17.6 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Stm1_N PF09598.10 KIY64966.1 - 0.037 14.9 1.1 0.081 13.8 1.1 1.5 1 0 0 1 1 1 0 Stm1 ER PF01133.17 KIY64966.1 - 0.047 13.7 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 Enhancer of rudimentary JTB PF05439.12 KIY64967.1 - 0.0011 19.0 3.9 0.004 17.2 3.8 1.9 1 1 0 1 1 1 1 Jumping translocation breakpoint protein (JTB) DLH PF01738.18 KIY64968.1 - 2.6e-19 69.6 0.1 9.1e-19 67.9 0.1 1.7 1 1 0 1 1 1 1 Dienelactone hydrolase family DLH PF01738.18 KIY64969.1 - 2.1e-19 69.9 0.0 3.2e-19 69.3 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 KIY64969.1 - 0.012 15.3 0.0 0.12 12.0 0.0 2.1 1 1 1 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIY64969.1 - 0.093 13.3 0.1 0.14 12.8 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DLH PF01738.18 KIY64970.1 - 5.4e-22 78.4 0.5 3.5e-21 75.8 0.5 1.9 1 1 0 1 1 1 1 Dienelactone hydrolase family NUDIX_2 PF13869.6 KIY64970.1 - 0.051 13.2 0.0 0.073 12.6 0.0 1.2 1 0 0 1 1 1 0 Nucleotide hydrolase Abhydrolase_1 PF00561.20 KIY64970.1 - 0.13 11.9 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DLH PF01738.18 KIY64972.1 - 1.7e-17 63.7 0.0 1.1e-16 61.0 0.0 1.9 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 KIY64972.1 - 0.044 14.4 0.0 0.066 13.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family PRRSV_2b PF07069.11 KIY64972.1 - 0.064 13.8 0.1 0.18 12.3 0.0 1.8 2 0 0 2 2 2 0 Porcine reproductive and respiratory syndrome virus 2b Tcp11 PF05794.13 KIY64973.1 - 2.7e-77 260.7 0.0 4.7e-77 259.9 0.0 1.3 1 1 0 1 1 1 1 T-complex protein 11 TFCD_C PF12612.8 KIY64974.1 - 7.2e-38 130.3 0.1 5.3e-37 127.5 0.0 2.7 3 0 0 3 3 3 1 Tubulin folding cofactor D C terminal Cnd1 PF12717.7 KIY64974.1 - 4.2e-05 23.7 0.5 0.078 13.0 0.0 5.2 6 1 0 6 6 6 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KIY64974.1 - 0.00028 20.9 7.7 0.27 11.6 0.1 6.7 6 0 0 6 6 6 1 HEAT repeat RTP1_C1 PF10363.9 KIY64974.1 - 0.0019 18.4 0.0 1.3 9.2 0.0 3.4 2 2 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 KIY64974.1 - 0.0026 18.2 4.1 18 6.0 0.0 5.2 5 0 0 5 5 5 1 HEAT-like repeat Vac14_Fab1_bd PF12755.7 KIY64974.1 - 0.0064 17.1 0.3 0.85 10.3 0.0 3.9 5 0 0 5 5 5 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 KIY64974.1 - 0.034 12.7 6.0 5.6 5.4 0.1 4.5 4 1 0 5 5 5 0 Adaptin N terminal region HEAT_2 PF13646.6 KIY64974.1 - 0.093 13.1 9.5 0.56 10.6 0.1 5.2 5 2 0 5 5 5 0 HEAT repeats ATP-synt_ab PF00006.25 KIY64975.1 - 2.6e-67 226.6 0.0 3.6e-67 226.1 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 KIY64975.1 - 1.2e-12 48.2 0.7 2.2e-12 47.3 0.7 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DUF3533 PF12051.8 KIY64975.1 - 0.15 10.9 0.0 0.25 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) Glyoxal_oxid_N PF07250.11 KIY64977.1 - 9.7e-30 103.5 0.4 2.6e-15 56.3 0.0 4.5 3 1 2 5 5 5 3 Glyoxal oxidase N-terminus DUF1929 PF09118.11 KIY64977.1 - 1.5e-22 79.6 0.0 3e-22 78.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.6 KIY64977.1 - 0.048 13.7 9.4 0.46 10.5 0.2 4.4 5 0 0 5 5 5 0 Galactose oxidase, central domain DUF4588 PF15251.6 KIY64979.1 - 8.8e-06 25.7 1.0 1.3e-05 25.1 1.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4588) PRP1_N PF06424.12 KIY64980.1 - 9.2e-51 172.1 6.0 9.2e-51 172.1 6.0 2.3 2 0 0 2 2 2 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 KIY64980.1 - 6.7e-27 91.9 31.1 0.0028 18.4 0.0 13.8 4 3 11 15 15 15 8 Tetratricopeptide repeat TPR_19 PF14559.6 KIY64980.1 - 1.1e-17 64.3 9.9 0.00018 22.0 0.2 8.7 5 3 5 10 10 10 5 Tetratricopeptide repeat TPR_2 PF07719.17 KIY64980.1 - 6.5e-08 32.1 3.9 10 6.5 0.0 9.2 10 0 0 10 10 8 1 Tetratricopeptide repeat TPR_16 PF13432.6 KIY64980.1 - 1.6e-07 31.9 17.0 0.028 15.1 0.0 7.4 6 2 1 8 8 7 2 Tetratricopeptide repeat TPR_6 PF13174.6 KIY64980.1 - 2.8e-06 27.6 13.4 0.18 12.5 0.0 8.7 11 0 0 11 11 7 2 Tetratricopeptide repeat TPR_9 PF13371.6 KIY64980.1 - 9.1e-05 22.5 9.2 4.8 7.4 0.0 5.9 6 0 0 6 6 5 2 Tetratricopeptide repeat Suf PF05843.14 KIY64980.1 - 0.0001 22.4 3.7 2.2 8.2 0.0 5.9 6 1 1 7 7 7 1 Suppressor of forked protein (Suf) TPR_12 PF13424.6 KIY64980.1 - 0.00022 21.4 9.4 0.34 11.2 0.0 6.5 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 KIY64980.1 - 0.00023 21.3 0.2 46 4.7 0.0 7.1 8 1 1 9 9 7 0 Tetratricopeptide repeat TPR_11 PF13414.6 KIY64980.1 - 0.0023 17.6 0.2 0.21 11.3 0.0 4.2 4 1 0 4 4 4 1 TPR repeat Thioredoxin_3 PF13192.6 KIY64980.1 - 0.064 13.3 0.1 1.6 8.8 0.0 3.2 3 0 0 3 3 3 0 Thioredoxin domain ANAPC3 PF12895.7 KIY64980.1 - 0.084 13.1 0.7 16 5.8 0.1 4.2 5 0 0 5 5 4 0 Anaphase-promoting complex, cyclosome, subunit 3 UPF0184 PF03670.13 KIY64980.1 - 0.19 12.1 1.1 0.8 10.1 1.1 2.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) TPR_8 PF13181.6 KIY64980.1 - 0.85 10.0 10.8 1e+02 3.5 0.0 7.5 12 0 0 12 12 7 0 Tetratricopeptide repeat TPR_10 PF13374.6 KIY64980.1 - 4.7 7.2 7.1 23 5.1 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat BUD22 PF09073.10 KIY64981.1 - 1.1e-69 235.9 39.7 4.9e-68 230.4 39.7 2.1 1 1 0 1 1 1 1 BUD22 Trp_halogenase PF04820.14 KIY64982.1 - 0.015 14.2 0.0 0.41 9.5 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase Glyco_hydro_17 PF00332.18 KIY64983.1 - 5.5e-15 55.7 6.1 2.2e-10 40.7 1.1 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 17 Pyr_redox_2 PF07992.14 KIY64985.1 - 0.0012 18.1 0.0 0.0025 17.1 0.0 1.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KIY64985.1 - 0.0015 17.4 0.0 0.63 8.8 0.0 2.7 3 0 0 3 3 3 2 Tryptophan halogenase Pyr_redox PF00070.27 KIY64985.1 - 0.018 15.6 0.0 0.036 14.6 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIY64985.1 - 0.057 13.0 0.2 1.9 8.0 0.1 2.6 1 1 2 3 3 3 0 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KIY64985.1 - 0.09 12.1 0.0 0.55 9.5 0.0 1.9 1 1 0 1 1 1 0 FAD dependent oxidoreductase Drf_GBD PF06371.13 KIY64986.1 - 9.8e-16 57.9 0.0 4.2e-12 46.0 0.1 2.9 3 0 0 3 3 3 2 Diaphanous GTPase-binding Domain TPR_12 PF13424.6 KIY64987.1 - 1.1e-10 41.6 2.0 0.0099 16.1 0.0 4.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 KIY64987.1 - 1.1e-08 34.5 2.0 0.21 11.8 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 KIY64987.1 - 1.3e-08 34.3 0.0 0.043 13.9 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KIY64987.1 - 1.2e-07 31.2 1.5 0.37 10.7 0.5 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat MIT PF04212.18 KIY64987.1 - 4.7e-05 23.4 0.1 0.039 14.0 0.0 3.0 3 0 0 3 3 3 2 MIT (microtubule interacting and transport) domain TPR_8 PF13181.6 KIY64987.1 - 8.2e-05 22.5 2.2 0.55 10.6 0.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 KIY64987.1 - 0.00016 21.4 4.1 0.61 10.0 0.1 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KIY64987.1 - 0.001 19.7 0.3 0.27 12.1 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 KIY64987.1 - 0.39 10.4 1.5 5.4 6.8 0.1 2.9 3 0 0 3 3 3 0 TPR repeat TPR_6 PF13174.6 KIY64987.1 - 1.1 10.0 3.5 17 6.3 0.1 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat Polyketide_cyc2 PF10604.9 KIY64988.1 - 0.048 13.9 0.2 0.71 10.1 0.2 2.1 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport ADH_zinc_N PF00107.26 KIY64989.1 - 1e-22 80.5 0.0 1.8e-22 79.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KIY64989.1 - 2.4e-10 41.6 0.0 4.4e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KIY64989.1 - 1.9e-08 34.2 0.0 3.6e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase TrkA_N PF02254.18 KIY64989.1 - 0.017 15.4 0.0 0.035 14.4 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain AAA_16 PF13191.6 KIY64990.1 - 1.8e-05 25.2 0.0 4.6e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain RNA12 PF10443.9 KIY64990.1 - 0.0012 17.6 0.0 4.3 6.0 0.0 3.1 2 1 1 3 3 3 3 RNA12 protein ATPase_2 PF01637.18 KIY64990.1 - 0.0096 15.9 0.0 0.022 14.7 0.0 1.6 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea DUF829 PF05705.14 KIY64991.1 - 3.9e-36 125.2 0.0 5.2e-36 124.8 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Pkinase PF00069.25 KIY64992.1 - 4.6e-44 150.8 0.0 1.5e-26 93.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIY64992.1 - 1.2e-19 70.6 0.0 6.9e-11 41.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KIY64992.1 - 2.2e-07 30.5 0.0 0.00054 19.4 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 KIY64992.1 - 0.0034 17.3 0.0 0.046 13.6 0.0 2.3 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kelch_5 PF13854.6 KIY64993.1 - 3.2e-20 71.7 0.3 7.8e-05 22.6 0.0 5.6 5 0 0 5 5 5 4 Kelch motif Kelch_4 PF13418.6 KIY64993.1 - 4.3e-18 65.1 12.1 0.00013 21.9 0.0 7.0 7 0 0 7 7 7 3 Galactose oxidase, central domain Kelch_6 PF13964.6 KIY64993.1 - 4.4e-15 55.4 5.6 0.0032 17.7 0.2 5.7 5 1 1 6 6 6 4 Kelch motif Kelch_3 PF13415.6 KIY64993.1 - 1.4e-10 41.2 21.7 0.0019 18.5 1.0 7.1 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_2 PF07646.15 KIY64993.1 - 5.7e-09 35.6 1.6 0.81 9.8 0.0 5.7 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.25 KIY64993.1 - 2.4e-08 33.4 0.0 0.12 12.0 0.0 4.9 4 0 0 4 4 4 3 Kelch motif SKG6 PF08693.10 KIY64993.1 - 0.024 14.1 4.2 0.058 12.8 4.2 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF1180 PF06679.12 KIY64993.1 - 0.13 12.7 0.0 0.13 12.7 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1180) DNA_pol3_tau_4 PF12168.8 KIY64993.1 - 5.1 7.7 6.4 1.4 9.5 0.6 2.3 2 0 0 2 2 2 0 DNA polymerase III subunits tau domain IV DnaB-binding DnaJ_C PF01556.18 KIY64996.1 - 2.1e-18 66.8 0.0 3.1e-18 66.3 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KIY64996.1 - 6.4e-15 55.0 0.0 1.1e-14 54.2 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain DUF908 PF06012.12 KIY64996.1 - 0.54 9.6 6.6 0.82 9.0 6.6 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Pribosyl_synth PF14572.6 KIY64997.1 - 0.083 12.9 0.0 0.083 12.9 0.0 1.7 2 0 0 2 2 2 0 Phosphoribosyl synthetase-associated domain NARP1 PF12569.8 KIY64997.1 - 0.24 10.3 12.1 0.43 9.4 12.1 1.5 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 RNB PF00773.19 KIY64998.1 - 6e-45 154.0 0.0 9.7e-45 153.3 0.0 1.4 1 0 0 1 1 1 1 RNB domain HAS-barrel PF09378.10 KIY64998.1 - 0.12 12.6 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 HAS barrel domain Glyco_hydro_10 PF00331.20 KIY64999.1 - 2.5e-108 362.0 0.0 2.9e-108 361.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.18 KIY64999.1 - 2.4e-11 43.4 12.6 4.5e-11 42.5 12.6 1.5 1 0 0 1 1 1 1 Fungal cellulose binding domain MSP1_C PF07462.11 KIY64999.1 - 0.62 8.7 3.5 0.86 8.2 3.5 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus DEAD PF00270.29 KIY65000.1 - 9.5e-35 119.9 0.3 2e-34 118.9 0.1 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIY65000.1 - 4.9e-28 97.7 0.7 1.4e-27 96.3 0.2 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 KIY65000.1 - 0.032 13.9 0.0 0.069 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain FAM193_C PF15914.5 KIY65000.1 - 0.1 12.4 0.1 0.23 11.2 0.1 1.6 1 0 0 1 1 1 0 FAM193 family C-terminal FAD_binding_3 PF01494.19 KIY65001.1 - 5.3e-13 48.9 0.0 1.7e-11 44.0 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KIY65001.1 - 0.0022 17.3 0.2 0.0091 15.3 0.2 1.9 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIY65001.1 - 0.004 16.8 0.1 1.5 8.3 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KIY65001.1 - 0.013 15.7 0.4 0.086 13.1 0.4 2.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KIY65001.1 - 0.026 13.6 0.2 0.089 11.9 0.3 1.7 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.12 KIY65001.1 - 0.029 13.4 0.1 0.37 9.8 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Rx_N PF18052.1 KIY65001.1 - 0.048 13.9 0.8 0.12 12.7 0.8 1.6 1 0 0 1 1 1 0 Rx N-terminal domain HI0933_like PF03486.14 KIY65001.1 - 0.11 11.1 0.1 9.2 4.8 0.2 2.1 2 0 0 2 2 2 0 HI0933-like protein CE2_N PF17996.1 KIY65002.1 - 6.6e-06 26.1 0.0 0.016 15.2 0.0 2.5 2 0 0 2 2 2 2 Carbohydrate esterase 2 N-terminal Herpes_gE PF02480.16 KIY65002.1 - 0.008 15.0 0.0 0.012 14.4 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Gly-zipper_YMGG PF13441.6 KIY65002.1 - 0.012 15.4 0.8 0.026 14.2 0.8 1.5 1 0 0 1 1 1 0 YMGG-like Gly-zipper DUF2690 PF10901.8 KIY65002.1 - 0.018 15.3 0.1 0.046 14.0 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2690) Yip1 PF04893.17 KIY65002.1 - 0.031 14.0 0.1 0.047 13.4 0.1 1.3 1 0 0 1 1 1 0 Yip1 domain PetG PF02529.15 KIY65002.1 - 0.054 13.4 0.8 0.099 12.5 0.8 1.4 1 0 0 1 1 1 0 Cytochrome B6-F complex subunit 5 PTP_tm PF18861.1 KIY65002.1 - 0.099 12.6 0.1 2 8.4 0.0 2.3 2 0 0 2 2 2 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J LRR_4 PF12799.7 KIY65004.1 - 0.012 16.0 0.5 12 6.5 0.1 3.2 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) Peptidase_C98 PF15499.6 KIY65004.1 - 0.19 11.2 0.0 0.28 10.6 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase LRR_2 PF07723.13 KIY65004.1 - 1.4 9.7 3.4 36 5.2 0.1 3.6 4 0 0 4 4 4 0 Leucine Rich Repeat zf-C2H2_jaz PF12171.8 KIY65005.1 - 1.3e-08 34.9 5.6 0.0011 19.2 0.6 3.2 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KIY65005.1 - 9.2e-07 29.2 10.7 0.022 15.6 0.5 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KIY65005.1 - 0.00014 22.1 11.5 0.0049 17.2 0.5 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-met PF12874.7 KIY65005.1 - 0.00068 20.0 8.3 0.043 14.2 0.3 3.1 3 0 0 3 3 3 2 Zinc-finger of C2H2 type XPA_N PF01286.18 KIY65005.1 - 0.0022 18.0 3.0 1.3 9.1 0.2 3.2 3 0 0 3 3 3 1 XPA protein N-terminal C1_1 PF00130.22 KIY65005.1 - 0.0023 17.8 6.5 0.029 14.2 1.8 2.3 1 1 1 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2H2_11 PF16622.5 KIY65005.1 - 0.0053 16.5 8.0 0.03 14.1 0.5 2.7 3 0 0 3 3 3 2 zinc-finger C2H2-type zf-FPG_IleRS PF06827.14 KIY65005.1 - 0.0054 16.6 4.9 0.048 13.5 1.9 3.1 2 1 0 2 2 2 1 Zinc finger found in FPG and IleRS LIM PF00412.22 KIY65005.1 - 0.0059 16.8 4.9 0.018 15.3 1.5 2.3 1 1 1 2 2 2 1 LIM domain Vps36-NZF-N PF16988.5 KIY65005.1 - 0.025 14.0 3.4 1.2 8.6 0.4 2.6 1 1 1 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Zn_ribbon_2 PF12674.7 KIY65005.1 - 0.029 15.0 1.7 1.2 9.8 0.8 2.4 2 0 0 2 2 2 0 Putative zinc ribbon domain DiS_P_DiS PF06750.13 KIY65005.1 - 0.033 14.3 1.0 0.86 9.8 0.4 2.3 1 1 1 2 2 2 0 Bacterial Peptidase A24 N-terminal domain zf-Di19 PF05605.12 KIY65005.1 - 0.036 14.3 10.2 0.73 10.2 1.3 2.6 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Zn-ribbon_8 PF09723.10 KIY65005.1 - 0.041 14.0 4.3 0.21 11.7 0.3 2.6 1 1 1 2 2 2 0 Zinc ribbon domain zinc_ribbon_15 PF17032.5 KIY65005.1 - 0.092 13.5 4.6 2 9.2 4.4 2.2 1 1 1 2 2 2 0 zinc-ribbon family zf_UBZ PF18439.1 KIY65005.1 - 0.19 11.4 5.1 12 5.5 0.6 3.2 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-C2H2_2 PF12756.7 KIY65005.1 - 0.23 11.8 8.8 1.5 9.2 0.8 2.7 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) FYVE PF01363.21 KIY65005.1 - 0.57 10.4 9.4 2.9 8.1 9.4 2.1 1 1 0 1 1 1 0 FYVE zinc finger zf-C2H2_9 PF16293.5 KIY65005.1 - 0.67 9.9 3.0 15 5.5 0.2 3.0 2 1 1 3 3 3 0 C2H2 type zinc-finger (1 copy) DZR PF12773.7 KIY65005.1 - 1.1 9.3 7.8 13 5.9 7.8 2.2 1 1 0 1 1 1 0 Double zinc ribbon zf-C2H2_6 PF13912.6 KIY65005.1 - 3.4 7.8 10.2 0.56 10.3 0.8 2.7 3 0 0 3 3 2 0 C2H2-type zinc finger YhfH PF14149.6 KIY65005.1 - 3.8 7.6 6.8 14 5.8 0.1 2.8 3 0 0 3 3 3 0 YhfH-like protein zinc_ribbon_2 PF13240.6 KIY65005.1 - 5.9 6.7 7.6 5.9 6.7 0.0 2.9 3 0 0 3 3 3 0 zinc-ribbon domain DNA_meth_N PF18284.1 KIY65006.1 - 0.21 11.5 0.5 2.4 8.1 0.5 2.2 1 1 1 2 2 2 0 DNA methylase N-terminal domain F-box-like PF12937.7 KIY65007.1 - 2.1e-11 43.5 2.2 2.9e-10 39.8 0.2 2.8 2 0 0 2 2 2 1 F-box-like F-box-like_2 PF13013.6 KIY65007.1 - 0.017 15.1 0.3 0.65 10.0 0.3 2.6 1 1 0 1 1 1 0 F-box-like domain LRR_4 PF12799.7 KIY65007.1 - 0.094 13.2 5.2 15 6.2 0.1 4.2 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) WD40_4 PF16300.5 KIY65008.1 - 0.089 12.7 0.9 3.6 7.6 0.3 2.8 2 1 0 2 2 2 0 Type of WD40 repeat Ank_4 PF13637.6 KIY65010.1 - 1.8e-24 85.7 0.7 6.2e-13 49.0 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KIY65010.1 - 4.4e-22 77.9 0.5 7.1e-13 48.5 0.1 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KIY65010.1 - 2.8e-20 72.7 0.1 4.6e-20 72.0 0.1 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KIY65010.1 - 4.8e-17 61.6 1.2 1e-06 28.9 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 KIY65010.1 - 5.3e-17 60.2 0.0 2.3e-06 27.5 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Gti1_Pac2 PF09729.9 KIY65011.1 - 1.8e-47 161.8 0.4 5.4e-38 130.9 0.2 2.0 1 1 1 2 2 2 2 Gti1/Pac2 family DUF5479 PF17575.2 KIY65011.1 - 0.018 15.6 0.0 0.027 15.0 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5479) UPF0086 PF01868.16 KIY65011.1 - 0.094 12.6 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function UPF0086 Aldo_ket_red PF00248.21 KIY65012.1 - 3.6e-39 134.7 0.0 5.8e-37 127.5 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family HSBP1 PF06825.12 KIY65013.1 - 2.5e-19 68.9 4.9 3.3e-19 68.5 4.9 1.2 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Baculo_PEP_C PF04513.12 KIY65013.1 - 0.014 15.5 0.1 0.018 15.1 0.1 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus FdhE PF04216.12 KIY65013.1 - 0.039 13.8 0.0 0.043 13.7 0.0 1.0 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation Gp58 PF07902.11 KIY65013.1 - 0.076 11.3 0.1 0.085 11.1 0.1 1.0 1 0 0 1 1 1 0 gp58-like protein SF-assemblin PF06705.11 KIY65013.1 - 0.091 12.1 0.1 0.11 11.8 0.1 1.1 1 0 0 1 1 1 0 SF-assemblin/beta giardin Sacchrp_dh_NADP PF03435.18 KIY65015.1 - 3.1e-18 66.3 0.1 4.7e-18 65.7 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 KIY65015.1 - 0.00022 21.3 0.1 0.00036 20.6 0.1 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 KIY65015.1 - 0.0061 17.1 0.0 0.016 15.7 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent EAV_GS PF01309.18 KIY65015.1 - 0.019 14.6 0.1 0.25 11.0 0.0 2.2 1 1 1 2 2 2 0 Equine arteritis virus small envelope glycoprotein NAD_binding_10 PF13460.6 KIY65015.1 - 0.061 13.2 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 NAD(P)H-binding Trehalase PF01204.18 KIY65017.1 - 3.6e-120 402.2 0.9 6e-110 368.5 0.0 2.1 2 0 0 2 2 2 2 Trehalase GDE_C PF06202.14 KIY65017.1 - 0.0014 17.7 0.1 0.0025 16.8 0.1 1.5 1 1 0 1 1 1 1 Amylo-alpha-1,6-glucosidase HLH PF00010.26 KIY65018.1 - 1.1e-16 60.5 5.6 2.4e-10 40.2 0.9 3.1 2 1 1 3 3 3 2 Helix-loop-helix DNA-binding domain Gti1_Pac2 PF09729.9 KIY65019.1 - 7.3e-52 176.1 0.8 6e-41 140.5 0.2 2.0 1 1 1 2 2 2 2 Gti1/Pac2 family RRM_1 PF00076.22 KIY65020.1 - 1.8e-08 34.1 0.0 4e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.17 KIY65020.1 - 4.8e-06 26.8 0.2 1.2e-05 25.5 0.2 1.7 1 0 0 1 1 1 1 PWI domain DNA_methylase PF00145.17 KIY65020.1 - 0.027 13.8 3.0 0.057 12.8 3.0 1.5 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase ExbD PF02472.16 KIY65020.1 - 0.6 10.3 4.2 0.4 10.8 0.8 2.2 2 0 0 2 2 2 0 Biopolymer transport protein ExbD/TolR Mac PF12464.8 KIY65020.1 - 2.8 8.3 6.6 44 4.4 2.4 3.4 2 1 1 3 3 3 0 Maltose acetyltransferase Macro PF01661.21 KIY65021.1 - 6.1e-21 74.7 0.0 7.1e-21 74.4 0.0 1.1 1 0 0 1 1 1 1 Macro domain HIT PF01230.23 KIY65022.1 - 5.7e-24 84.7 0.1 9e-24 84.1 0.1 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KIY65022.1 - 1.6e-09 38.2 0.1 2.6e-09 37.5 0.1 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 KIY65022.1 - 0.00016 21.5 0.4 0.00035 20.4 0.4 1.6 1 1 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 DIOX_N PF14226.6 KIY65023.1 - 8.4e-33 113.6 0.0 1.2e-32 113.1 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KIY65023.1 - 1.1e-18 67.6 0.0 2.1e-18 66.7 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily XFP_N PF09364.10 KIY65023.1 - 0.11 11.2 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 XFP N-terminal domain SLAC1 PF03595.17 KIY65024.1 - 1.6e-57 195.2 45.5 1.8e-57 195.0 45.5 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel RSN1_7TM PF02714.15 KIY65025.1 - 3e-85 285.9 23.1 3e-85 285.9 23.1 1.7 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KIY65025.1 - 1.5e-37 128.8 4.9 1.5e-37 128.8 4.9 2.4 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KIY65025.1 - 2.8e-32 112.4 0.0 4.8e-32 111.6 0.0 1.4 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 KIY65025.1 - 9.2e-06 25.7 0.1 2e-05 24.6 0.1 1.6 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter DUF1772 PF08592.11 KIY65025.1 - 9.5 6.5 9.7 0.29 11.4 0.5 3.1 2 2 0 2 2 2 0 Domain of unknown function (DUF1772) RAP1 PF07218.11 KIY65026.1 - 0.9 7.7 3.9 1.1 7.5 3.9 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PhoD PF09423.10 KIY65027.1 - 1.4e-05 24.3 0.3 0.12 11.4 0.0 2.5 3 0 0 3 3 3 2 PhoD-like phosphatase APC1_C PF18122.1 KIY65028.1 - 5.6e-30 104.5 0.0 1.2e-29 103.4 0.0 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex sub unit 1 C-terminal domain ANAPC1 PF12859.7 KIY65028.1 - 1e-06 29.3 4.4 0.0014 19.2 0.0 3.0 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 1 PC_rep PF01851.22 KIY65028.1 - 0.00018 21.8 5.3 1.1 9.8 0.1 5.2 5 0 0 5 5 5 2 Proteasome/cyclosome repeat 2Fe-2S_thioredx PF01257.19 KIY65030.1 - 5.4e-59 198.2 0.0 6.5e-59 197.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin UQ_con PF00179.26 KIY65032.1 - 3.9e-19 68.7 0.0 5.8e-19 68.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KIY65032.1 - 0.0099 16.2 0.0 0.019 15.2 0.0 1.5 1 0 0 1 1 1 1 RWD domain Rubredoxin PF00301.20 KIY65032.1 - 0.06 13.4 1.7 0.13 12.3 0.2 2.1 2 0 0 2 2 2 0 Rubredoxin NYN PF01936.18 KIY65034.1 - 2.2e-07 31.4 0.0 4.3e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 NYN domain NYN PF01936.18 KIY65036.1 - 3.2e-07 30.9 0.0 6e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 NYN domain Med1 PF10744.9 KIY65037.1 - 0.0013 17.9 0.0 0.17 10.9 0.0 2.2 2 0 0 2 2 2 2 Mediator of RNA polymerase II transcription subunit 1 NYN PF01936.18 KIY65038.1 - 2.3e-22 80.1 0.0 3.3e-22 79.6 0.0 1.2 1 0 0 1 1 1 1 NYN domain Actin PF00022.19 KIY65039.1 - 6.3e-28 97.5 0.0 2e-23 82.7 0.0 2.5 2 1 0 2 2 2 2 Actin Actin_micro PF17003.5 KIY65039.1 - 3.3e-12 46.3 0.8 4.7e-05 22.7 0.1 3.1 3 0 0 3 3 3 2 Putative actin-like family FtsA PF14450.6 KIY65039.1 - 0.055 13.9 0.0 0.4 11.1 0.0 2.2 1 1 0 1 1 1 0 Cell division protein FtsA PilM_2 PF11104.8 KIY65039.1 - 0.078 12.0 0.0 6.4 5.7 0.0 2.2 2 0 0 2 2 2 0 Type IV pilus assembly protein PilM; Mog1 PF04603.12 KIY65041.1 - 5e-41 140.3 0.5 5.9e-41 140.1 0.5 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein GvpO PF05800.11 KIY65041.1 - 0.29 11.1 1.7 16 5.5 0.1 2.9 2 1 0 3 3 3 0 Gas vesicle synthesis protein GvpO RNase_T PF00929.24 KIY65042.1 - 3.1e-18 66.9 0.0 5.4e-18 66.1 0.0 1.4 1 1 0 1 1 1 1 Exonuclease CMS1 PF14617.6 KIY65043.1 - 6.7e-72 241.8 0.6 8.3e-72 241.5 0.6 1.0 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.29 KIY65043.1 - 0.0037 17.1 0.0 0.0067 16.2 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Ribosomal_S17_N PF16205.5 KIY65043.1 - 0.029 14.7 1.0 0.059 13.7 1.0 1.5 1 0 0 1 1 1 0 Ribosomal_S17 N-terminal CDC45 PF02724.14 KIY65043.1 - 2.2 6.5 5.1 2.4 6.3 5.1 1.1 1 0 0 1 1 1 0 CDC45-like protein L31 PF09784.9 KIY65044.1 - 6.3e-43 145.4 0.1 7e-43 145.2 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 PRP21_like_P PF12230.8 KIY65045.1 - 2.5e-49 168.1 10.8 2.5e-49 168.1 10.8 1.7 2 0 0 2 2 2 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 KIY65045.1 - 3.5e-33 113.4 1.3 5.4e-16 58.3 0.0 2.5 2 0 0 2 2 2 2 Surp module ubiquitin PF00240.23 KIY65045.1 - 3.2e-10 39.6 0.0 8.7e-10 38.2 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family zf_UBZ PF18439.1 KIY65045.1 - 0.0096 15.5 0.4 0.019 14.5 0.4 1.5 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger Rad60-SLD PF11976.8 KIY65045.1 - 0.042 13.7 0.0 0.096 12.5 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Helitron_like_N PF14214.6 KIY65050.1 - 2.1e-08 34.6 0.0 2.2e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Helitron_like_N PF14214.6 KIY65051.1 - 9.1e-09 35.8 0.0 1.8e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.14 KIY65052.1 - 5.1e-12 45.6 0.0 5.3e-12 45.6 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KIY65052.1 - 3e-09 36.9 0.0 3.8e-09 36.6 0.0 1.0 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KIY65052.1 - 4.4e-06 27.1 0.1 7.6e-06 26.3 0.1 1.4 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KIY65052.1 - 0.00037 20.8 0.0 0.00071 19.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KIY65052.1 - 0.064 13.6 0.1 0.16 12.3 0.1 1.7 1 1 1 2 2 2 0 AAA ATPase domain NTPase_1 PF03266.15 KIY65052.1 - 0.13 12.2 0.0 16 5.4 0.0 2.1 2 0 0 2 2 2 0 NTPase Mg_chelatase PF01078.21 KIY65052.1 - 0.14 11.5 0.0 0.27 10.6 0.0 1.5 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KIY65052.1 - 0.19 11.4 1.0 0.9 9.2 0.2 2.1 1 1 1 2 2 2 0 IstB-like ATP binding protein PIF1 PF05970.14 KIY65053.1 - 0.014 14.6 0.0 0.016 14.4 0.0 1.1 1 0 0 1 1 1 0 PIF1-like helicase Chitin_synth_2 PF03142.15 KIY65055.1 - 1.2e-235 783.2 0.4 1.6e-235 782.8 0.4 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 KIY65055.1 - 2.6e-100 336.6 0.0 2.5e-99 333.4 0.0 2.1 1 1 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.28 KIY65055.1 - 3.7e-18 65.4 0.2 5.7e-13 48.8 0.0 2.8 2 1 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain DEK_C PF08766.11 KIY65055.1 - 1.6e-15 56.8 0.1 4.1e-15 55.4 0.1 1.8 1 0 0 1 1 1 1 DEK C terminal domain Glyco_tranf_2_3 PF13641.6 KIY65055.1 - 9.2e-15 55.2 0.0 1.2e-12 48.2 0.0 2.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 KIY65055.1 - 6.5e-13 49.0 3.4 2.2e-12 47.3 3.4 1.9 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 KIY65055.1 - 5.6e-08 32.8 0.0 0.00021 21.1 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KIY65055.1 - 5e-05 22.8 0.0 0.011 15.2 0.0 2.6 2 0 0 2 2 2 2 Glycosyl transferase family 21 DSPc PF00782.20 KIY65056.1 - 2e-48 163.6 0.0 2.5e-32 111.5 0.0 2.3 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 KIY65056.1 - 0.00014 22.1 0.8 0.052 13.8 0.1 2.4 2 0 0 2 2 2 2 Rit1 DUSP-like domain Y_phosphatase PF00102.27 KIY65056.1 - 0.035 13.7 0.9 0.047 13.2 0.1 1.7 2 0 0 2 2 2 0 Protein-tyrosine phosphatase Myotub-related PF06602.14 KIY65056.1 - 0.11 11.4 0.4 10 5.0 0.0 2.1 2 0 0 2 2 2 0 Myotubularin-like phosphatase domain His_Phos_2 PF00328.22 KIY65057.1 - 2.9e-55 188.2 0.0 4.3e-55 187.6 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Avidin PF01382.17 KIY65058.1 - 6.1e-25 87.9 4.3 7.6e-25 87.6 4.3 1.1 1 0 0 1 1 1 1 Avidin family Avidin PF01382.17 KIY65059.1 - 3.7e-26 91.9 7.1 4.3e-26 91.6 7.1 1.1 1 0 0 1 1 1 1 Avidin family Avidin PF01382.17 KIY65060.1 - 8.6e-26 90.7 7.0 1e-25 90.5 7.0 1.0 1 0 0 1 1 1 1 Avidin family Avidin PF01382.17 KIY65061.1 - 6.1e-27 94.4 4.5 7.1e-27 94.2 4.5 1.0 1 0 0 1 1 1 1 Avidin family Abhydrolase_3 PF07859.13 KIY65063.1 - 4.8e-15 56.0 0.0 7.9e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KIY65063.1 - 8.3e-07 28.2 0.0 5.9e-06 25.4 0.0 2.3 2 1 0 2 2 2 1 Steryl acetyl hydrolase MFS_2 PF13347.6 KIY65067.1 - 1.1e-13 50.5 12.0 1.1e-13 50.5 12.0 2.3 2 0 0 2 2 2 1 MFS/sugar transport protein MFS_1 PF07690.16 KIY65067.1 - 4.6e-09 35.7 34.2 4.6e-09 35.7 34.2 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily BT1 PF03092.16 KIY65067.1 - 0.021 13.0 4.6 0.034 12.4 4.6 1.3 1 0 0 1 1 1 0 BT1 family Avidin PF01382.17 KIY65068.1 - 3.3e-24 85.6 10.9 3.9e-24 85.3 10.9 1.1 1 0 0 1 1 1 1 Avidin family MVL PF12151.8 KIY65068.1 - 0.7 9.8 8.2 4.9 7.1 1.8 3.1 2 1 1 3 3 3 0 Mannan-binding protein Pkinase PF00069.25 KIY65070.1 - 0.017 14.5 0.0 0.068 12.5 0.0 1.9 1 1 0 2 2 2 0 Protein kinase domain RhoGAP PF00620.27 KIY65071.1 - 3.1e-10 40.1 0.3 7.1e-10 38.9 0.0 1.7 2 0 0 2 2 2 1 RhoGAP domain DEP PF00610.21 KIY65071.1 - 2.3e-07 30.8 0.0 3.9e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) FCH PF00611.23 KIY65071.1 - 0.00011 22.4 0.0 0.00026 21.2 0.0 1.7 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain Ribonucleas_3_3 PF14622.6 KIY65072.1 - 8e-10 39.0 0.0 1.4e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.26 KIY65072.1 - 2.2e-05 25.1 0.0 5.4e-05 23.8 0.0 1.7 2 0 0 2 2 2 1 Double-stranded RNA binding motif Ribonuclease_3 PF00636.26 KIY65072.1 - 0.001 19.6 0.0 0.0019 18.8 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease III domain PhzC-PhzF PF02567.16 KIY65073.1 - 4.3e-31 108.4 0.0 5.3e-31 108.1 0.0 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Pro_racemase PF05544.11 KIY65073.1 - 0.00012 21.2 0.0 0.00018 20.7 0.0 1.2 1 0 0 1 1 1 1 Proline racemase SopA_C PF13979.6 KIY65073.1 - 0.053 13.3 0.0 0.088 12.5 0.0 1.3 1 0 0 1 1 1 0 SopA-like catalytic domain ABC_tran PF00005.27 KIY65074.1 - 8.4e-27 94.4 0.0 2.1e-26 93.1 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KIY65074.1 - 1.3e-10 41.6 1.8 0.00011 22.1 0.1 2.5 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KIY65074.1 - 1.5e-07 31.1 0.0 0.0061 16.0 0.0 2.2 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 KIY65074.1 - 3.5e-06 27.0 0.0 0.0002 21.2 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 KIY65074.1 - 0.00065 20.3 0.0 0.0011 19.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KIY65074.1 - 0.0017 18.1 0.0 0.0034 17.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 KIY65074.1 - 0.005 17.2 0.2 0.021 15.2 0.1 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 KIY65074.1 - 0.0072 16.1 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KIY65074.1 - 0.023 14.0 0.0 0.048 12.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.6 KIY65074.1 - 0.027 14.7 0.0 0.22 11.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_27 PF13514.6 KIY65074.1 - 0.034 13.8 0.0 0.061 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KIY65074.1 - 0.13 12.3 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.25 KIY65074.1 - 0.15 11.7 0.0 0.52 9.9 0.1 1.7 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Peptidase_M20 PF01546.28 KIY65075.1 - 1.3e-28 100.1 0.0 3.8e-28 98.6 0.0 1.8 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KIY65075.1 - 2.1e-09 37.3 0.0 4.2e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KIY65075.1 - 6.6e-05 22.7 0.0 0.00011 21.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KIY65076.1 - 4.7e-30 104.8 0.2 6.9e-30 104.3 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KIY65076.1 - 8.9e-10 38.5 0.0 1.9e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KIY65076.1 - 0.0011 18.7 0.1 0.003 17.3 0.1 1.7 1 1 0 1 1 1 1 Peptidase family M28 ADH_zinc_N PF00107.26 KIY65077.1 - 1.2e-10 41.5 0.0 2.6e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIY65077.1 - 2e-07 30.8 0.0 3.7e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KIY65077.1 - 0.005 17.9 0.0 0.0083 17.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase MgtE_N PF03448.17 KIY65077.1 - 0.15 12.7 0.0 0.46 11.1 0.0 1.8 2 0 0 2 2 2 0 MgtE intracellular N domain zf_CCCH_4 PF18345.1 KIY65078.1 - 5.6e-16 58.0 15.2 5.7e-08 32.6 4.6 2.0 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 KIY65078.1 - 6.5e-15 54.5 8.1 1.6e-07 31.0 1.6 2.1 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH PF00642.24 KIY65078.1 - 2.1e-13 49.8 4.8 2.1e-06 27.5 1.5 2.1 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KIY65078.1 - 7.3e-09 36.3 7.5 0.00045 20.9 1.2 2.0 1 1 1 2 2 2 2 Torus domain zf-CCCH_2 PF14608.6 KIY65078.1 - 1.6e-07 31.5 10.9 0.0019 18.6 1.7 2.2 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 KIY65078.1 - 2.4e-06 27.7 2.9 2.6e-06 27.6 2.9 1.1 1 0 0 1 1 1 1 Zinc-finger containing family Defensin_int PF17858.1 KIY65078.1 - 0.0026 17.7 4.3 0.016 15.2 1.0 2.2 1 1 0 2 2 2 1 Platypus intermediate defensin-like peptide Lustrin_cystein PF14625.6 KIY65078.1 - 1.1 9.6 9.0 4.3 7.8 1.3 2.1 1 1 1 2 2 2 0 Lustrin, cysteine-rich repeated domain IBR PF01485.21 KIY65079.1 - 0.00024 21.2 5.7 0.00055 20.1 5.7 1.6 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 KIY65079.1 - 0.01 16.1 0.3 0.01 16.1 0.3 3.3 2 1 1 3 3 3 0 Ring finger domain RRM_1 PF00076.22 KIY65079.1 - 0.012 15.4 0.0 0.64 9.9 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Prok-RING_2 PF14445.6 KIY65079.1 - 0.15 12.2 3.6 1.1 9.5 2.6 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 2 Coronavirus_5 PF05528.11 KIY65079.1 - 3.3 7.8 6.6 78 3.4 1.1 3.9 4 0 0 4 4 4 0 Coronavirus gene 5 protein YEATS PF03366.16 KIY65080.1 - 0.011 15.6 0.0 0.021 14.8 0.0 1.5 1 0 0 1 1 1 0 YEATS family CbtA PF09490.10 KIY65082.1 - 0.61 9.8 8.3 0.2 11.4 4.9 1.9 1 1 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) DUF1308 PF07000.11 KIY65083.1 - 1.3e-05 25.2 1.6 0.0085 16.0 0.1 3.7 3 1 1 4 4 4 2 Protein of unknown function (DUF1308) DUF4757 PF15949.5 KIY65083.1 - 0.028 14.9 1.8 0.028 14.9 1.8 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4757) Vps16_C PF04840.12 KIY65084.1 - 0.09 11.8 12.3 0.65 9.0 1.3 3.4 1 1 2 3 3 3 0 Vps16, C-terminal region MRP_L53 PF10780.9 KIY65084.1 - 0.27 11.5 2.0 9.4 6.5 0.1 3.7 3 0 0 3 3 3 0 39S ribosomal protein L53/MRP-L53 DUF5304 PF17230.2 KIY65084.1 - 2 8.7 0.0 2 8.7 0.0 3.4 2 1 1 3 3 3 0 Family of unknown function (DUF5304) Peptidase_S10 PF00450.22 KIY65085.1 - 4.5e-94 316.2 0.0 5.7e-94 315.9 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.7 KIY65085.1 - 0.0022 18.6 0.1 0.047 14.3 0.1 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Adaptin_N PF01602.20 KIY65086.1 - 6.2e-143 477.1 8.9 7.2e-143 476.9 8.9 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 KIY65086.1 - 2.9e-22 79.1 0.2 5.9e-22 78.1 0.2 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 KIY65086.1 - 6.5e-10 39.3 11.0 1.1e-07 32.0 0.3 4.6 4 2 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KIY65086.1 - 0.016 15.4 2.5 85 3.8 0.0 5.4 5 0 0 5 5 5 0 HEAT repeat HEAT_2 PF13646.6 KIY65086.1 - 0.018 15.4 5.3 1.6 9.2 0.2 4.7 5 0 0 5 5 5 0 HEAT repeats Peptidase_M73 PF12389.8 KIY65086.1 - 0.059 13.2 0.2 0.099 12.5 0.2 1.3 1 0 0 1 1 1 0 Camelysin metallo-endopeptidase FAA_hydrolase_N PF09298.11 KIY65086.1 - 0.13 12.4 0.1 0.59 10.3 0.1 2.2 1 0 0 1 1 1 0 Fumarylacetoacetase N-terminal CN_hydrolase PF00795.22 KIY65087.1 - 3.9e-41 141.1 0.0 5.7e-41 140.6 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 KIY65087.1 - 3.6e-22 78.7 0.0 2.3e-21 76.0 0.0 2.1 1 1 0 1 1 1 1 NAD synthase CTP_transf_like PF01467.26 KIY65088.1 - 3e-14 53.4 0.0 4.2e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase-like 2OG-FeII_Oxy_3 PF13640.6 KIY65089.1 - 1.1e-11 45.5 0.0 3e-11 44.1 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Chromo PF00385.24 KIY65090.1 - 0.15 12.0 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Integrase_H2C2 PF17921.1 KIY65092.1 - 2.7e-07 30.6 0.6 4.4e-07 29.9 0.6 1.3 1 0 0 1 1 1 1 Integrase zinc binding domain SNF2_N PF00176.23 KIY65092.1 - 0.098 11.4 0.1 0.1 11.3 0.1 1.1 1 0 0 1 1 1 0 SNF2 family N-terminal domain PIF1 PF05970.14 KIY65096.1 - 0.0082 15.3 0.0 0.0094 15.2 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase PIF1 PF05970.14 KIY65097.1 - 6.6e-14 51.8 0.0 7.6e-14 51.7 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KIY65097.1 - 4.8e-09 36.2 0.0 5.7e-09 36.0 0.0 1.0 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KIY65097.1 - 2.3e-05 24.7 0.3 5.3e-05 23.6 0.3 1.6 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KIY65097.1 - 0.00028 21.2 0.0 0.00035 20.8 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.6 KIY65097.1 - 0.013 15.3 0.0 0.016 15.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system IstB_IS21 PF01695.17 KIY65097.1 - 0.028 14.2 0.2 0.13 12.0 0.2 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein Bac_DnaA PF00308.18 KIY65097.1 - 0.34 10.7 0.9 24 4.7 0.0 2.8 1 1 2 3 3 3 0 Bacterial dnaA protein Helitron_like_N PF14214.6 KIY65099.1 - 2.3e-08 34.5 0.0 4.3e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Helitron_like_N PF14214.6 KIY65100.1 - 2.6e-15 57.2 0.1 3.4e-15 56.8 0.1 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus SLC35F PF06027.12 KIY65100.1 - 0.16 11.5 0.0 0.22 11.0 0.0 1.1 1 0 0 1 1 1 0 Solute carrier family 35 Viral_NABP PF05515.11 KIY65101.1 - 0.12 12.3 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Viral nucleic acid binding FAM176 PF14851.6 KIY65102.1 - 0.032 13.9 0.7 0.062 13.0 0.2 1.7 2 0 0 2 2 2 0 FAM176 family Tropomyosin PF00261.20 KIY65104.1 - 0.0019 17.6 2.7 0.0024 17.3 2.7 1.1 1 0 0 1 1 1 1 Tropomyosin zf-RING_14 PF17978.1 KIY65104.1 - 0.026 15.0 2.2 0.045 14.2 2.2 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain APG6_N PF17675.1 KIY65104.1 - 0.043 14.3 0.3 0.062 13.8 0.3 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region SO_alpha_A3 PF17806.1 KIY65104.1 - 0.13 12.6 0.3 7.6 6.9 0.1 2.2 2 0 0 2 2 2 0 Sarcosine oxidase A3 domain RabGAP-TBC PF00566.18 KIY65105.1 - 0.052 13.2 0.2 0.091 12.4 0.2 1.4 1 0 0 1 1 1 0 Rab-GTPase-TBC domain TrpP PF17099.5 KIY65107.1 - 0.057 13.2 0.9 0.11 12.2 0.0 1.8 2 0 0 2 2 2 0 Tryptophan transporter TrpP Brix PF04427.18 KIY65109.1 - 1.1e-25 90.9 0.0 1.6e-25 90.3 0.0 1.3 1 0 0 1 1 1 1 Brix domain HMG_box PF00505.19 KIY65110.1 - 2.9e-10 40.4 0.7 5.2e-10 39.6 0.7 1.4 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KIY65110.1 - 3.1e-05 24.5 0.1 3.6e-05 24.3 0.1 1.1 1 0 0 1 1 1 1 HMG-box domain PTR2 PF00854.21 KIY65111.1 - 9.7e-80 268.3 5.4 1.3e-79 267.9 5.4 1.1 1 0 0 1 1 1 1 POT family Sugar_tr PF00083.24 KIY65111.1 - 1.4 7.7 19.6 1 8.2 7.1 3.0 2 1 0 2 2 2 0 Sugar (and other) transporter GDA1_CD39 PF01150.17 KIY65112.1 - 1.2e-97 327.3 0.0 1.6e-97 326.9 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.16 KIY65112.1 - 0.055 12.9 0.0 0.086 12.3 0.0 1.2 1 0 0 1 1 1 0 Ppx/GppA phosphatase family Tmemb_14 PF03647.13 KIY65114.1 - 9.1e-18 64.8 5.5 1.1e-17 64.5 5.5 1.1 1 0 0 1 1 1 1 Transmembrane proteins 14C NUT PF12881.7 KIY65115.1 - 5 5.4 6.8 5 5.4 6.8 1.1 1 0 0 1 1 1 0 NUT protein Methyltransf_28 PF02636.17 KIY65116.1 - 1.4e-39 136.3 0.0 1.9e-39 135.9 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_12 PF08242.12 KIY65116.1 - 0.0021 18.8 0.0 0.0088 16.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain RrnaAD PF00398.20 KIY65116.1 - 0.0081 15.3 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase NepR PF18557.1 KIY65116.1 - 0.18 11.5 0.9 3.4 7.4 0.4 2.4 2 0 0 2 2 2 0 Anti-sigma factor NepR PRMT5 PF05185.16 KIY65116.1 - 0.19 11.6 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase MMS19_N PF14500.6 KIY65117.1 - 3.2e-94 315.4 0.1 2.9e-93 312.2 0.0 2.6 2 0 0 2 2 2 1 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.8 KIY65117.1 - 7.3e-89 298.8 0.3 1.1e-87 294.8 0.0 2.9 3 0 0 3 3 3 1 RNAPII transcription regulator C-terminal HEAT_EZ PF13513.6 KIY65117.1 - 1.1e-05 25.8 5.0 0.022 15.3 0.4 6.4 7 1 1 8 8 8 1 HEAT-like repeat HEAT_2 PF13646.6 KIY65117.1 - 8.2e-05 22.9 13.3 0.0077 16.6 0.3 6.3 6 1 0 7 7 7 1 HEAT repeats HEAT PF02985.22 KIY65117.1 - 0.16 12.3 9.4 85 3.8 0.0 6.9 7 0 0 7 7 7 0 HEAT repeat DUF3385 PF11865.8 KIY65117.1 - 0.16 11.8 0.2 5.7 6.8 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3385) Tti2 PF10521.9 KIY65117.1 - 0.47 10.0 2.4 7 6.1 0.1 3.6 3 1 0 3 3 3 0 Tti2 family HEAT_PBS PF03130.16 KIY65117.1 - 0.86 10.5 2.9 64 4.7 0.0 4.1 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat DASH_Dam1 PF08653.10 KIY65118.1 - 1.2e-14 53.8 0.1 1.9e-14 53.2 0.1 1.3 1 0 0 1 1 1 1 DASH complex subunit Dam1 DUF2397 PF09660.10 KIY65118.1 - 0.017 14.1 6.7 0.026 13.4 6.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2397) NDUF_B7 PF05676.13 KIY65119.1 - 1.9e-30 104.3 2.4 2.3e-30 104.1 2.4 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) SelR PF01641.18 KIY65121.1 - 1.8e-53 179.7 0.4 2.1e-53 179.5 0.4 1.0 1 0 0 1 1 1 1 SelR domain Yippee-Mis18 PF03226.14 KIY65121.1 - 0.0055 16.9 0.1 0.0095 16.1 0.1 1.5 1 1 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DZR PF12773.7 KIY65121.1 - 0.038 14.0 0.4 3.8 7.6 0.1 2.3 2 0 0 2 2 2 0 Double zinc ribbon zinc_ribbon_10 PF10058.9 KIY65121.1 - 0.073 12.8 0.1 1.2 9.0 0.0 2.2 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein MBOAT_2 PF13813.6 KIY65122.1 - 1.8e-15 56.9 1.3 1.8e-15 56.9 1.3 1.9 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family MBOAT_2 PF13813.6 KIY65123.1 - 6.6e-13 48.7 1.4 6.6e-13 48.7 1.4 2.4 2 1 0 2 2 2 1 Membrane bound O-acyl transferase family PulG PF11773.8 KIY65124.1 - 0.0099 15.7 0.8 0.013 15.3 0.8 1.2 1 0 0 1 1 1 1 Type II secretory pathway pseudopilin DYW_deaminase PF14432.6 KIY65124.1 - 0.06 13.2 0.9 0.064 13.1 0.9 1.1 1 0 0 1 1 1 0 DYW family of nucleic acid deaminases Pkinase PF00069.25 KIY65126.1 - 9.2e-67 225.2 0.0 1.1e-66 225.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY65126.1 - 2.9e-44 151.3 0.0 3.7e-44 150.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY65126.1 - 2.2e-09 37.1 0.0 3.2e-06 26.7 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 KIY65126.1 - 7.2e-06 25.0 0.0 1.2e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KIY65126.1 - 0.0025 17.2 0.0 0.0037 16.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KIY65126.1 - 0.0092 15.6 0.0 0.013 15.1 0.0 1.4 1 1 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KIY65126.1 - 0.012 15.5 0.0 0.9 9.4 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family AXE1 PF05448.12 KIY65126.1 - 0.017 13.8 0.0 0.021 13.5 0.0 1.1 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) ABC_membrane PF00664.23 KIY65127.1 - 1.9e-54 185.2 29.7 2.2e-27 96.4 13.9 3.5 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 KIY65127.1 - 5.7e-44 150.0 0.2 9e-27 94.3 0.1 2.8 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KIY65127.1 - 1.1e-12 47.9 3.7 0.004 16.6 0.1 4.2 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KIY65127.1 - 2.1e-06 28.4 2.2 0.00086 19.9 0.0 2.7 3 0 0 3 3 2 2 AAA domain AAA_21 PF13304.6 KIY65127.1 - 5.3e-06 26.5 3.4 0.08 12.7 0.1 4.4 3 1 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KIY65127.1 - 8.8e-05 22.9 2.6 0.24 11.8 0.0 2.9 3 0 0 3 3 2 2 AAA ATPase domain AAA_29 PF13555.6 KIY65127.1 - 0.00032 20.4 0.1 1.1 9.0 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.6 KIY65127.1 - 0.00036 20.1 0.0 0.82 9.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 KIY65127.1 - 0.00061 19.9 0.2 0.56 10.3 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIY65127.1 - 0.0012 18.8 0.0 0.54 10.1 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase DUF87 PF01935.17 KIY65127.1 - 0.0015 18.7 0.2 0.04 14.0 0.1 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain T2SSE PF00437.20 KIY65127.1 - 0.0017 17.5 0.2 0.18 10.8 0.0 2.6 3 0 0 3 3 3 1 Type II/IV secretion system protein ATPase_2 PF01637.18 KIY65127.1 - 0.0017 18.3 0.0 0.14 12.1 0.0 2.7 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_7 PF12775.7 KIY65127.1 - 0.0022 17.6 0.0 0.5 9.9 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_5 PF07728.14 KIY65127.1 - 0.0025 17.8 0.2 6.9 6.7 0.1 3.8 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 KIY65127.1 - 0.0026 17.5 0.0 5 6.8 0.0 3.2 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_22 PF13401.6 KIY65127.1 - 0.0028 17.9 0.4 3.1 8.1 0.0 3.0 2 1 0 2 2 2 1 AAA domain Adeno_IVa2 PF02456.15 KIY65127.1 - 0.0032 16.3 0.8 0.03 13.1 0.0 2.4 3 0 0 3 3 3 1 Adenovirus IVa2 protein AAA PF00004.29 KIY65127.1 - 0.0032 17.9 0.6 0.23 11.9 0.2 3.2 3 2 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 KIY65127.1 - 0.0064 16.3 0.1 0.055 13.2 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain DPM3 PF08285.11 KIY65127.1 - 0.013 15.6 10.4 0.087 13.0 0.1 4.0 3 0 0 3 3 3 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) AAA_18 PF13238.6 KIY65127.1 - 0.027 15.0 0.0 15 6.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 KIY65127.1 - 0.027 14.5 0.8 1.6 8.8 0.0 2.8 2 0 0 2 2 2 0 Dynamin family FtsK_SpoIIIE PF01580.18 KIY65127.1 - 0.043 13.2 0.1 5.5 6.3 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family ResIII PF04851.15 KIY65127.1 - 0.061 13.3 0.0 3.9 7.4 0.0 2.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit RNA_helicase PF00910.22 KIY65127.1 - 0.086 13.2 0.0 14 6.1 0.0 2.7 2 0 0 2 2 2 0 RNA helicase PduV-EutP PF10662.9 KIY65127.1 - 0.092 12.5 0.3 4.8 6.9 0.0 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Roc PF08477.13 KIY65127.1 - 0.11 12.7 0.1 18 5.6 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase PhoH PF02562.16 KIY65127.1 - 0.11 11.9 0.0 1.9 7.9 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein Pox_A32 PF04665.12 KIY65127.1 - 0.15 11.5 0.3 4.3 6.7 0.1 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_11 PF13086.6 KIY65127.1 - 0.18 11.6 0.3 0.99 9.1 0.1 2.3 2 1 0 2 2 1 0 AAA domain GWT1 PF06423.12 KIY65127.1 - 1.7 8.8 5.6 4.9 7.3 0.0 3.5 3 0 0 3 3 3 0 GWT1 Nucleoporin_N PF08801.11 KIY65128.1 - 5.3e-69 233.0 0.0 1e-68 232.1 0.0 1.4 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 KIY65128.1 - 2.9e-28 99.0 1.8 4.2e-28 98.4 1.8 1.2 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal adh_short PF00106.25 KIY65129.1 - 1.7e-12 47.2 0.0 2.7e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIY65129.1 - 3.3e-08 33.4 0.1 4.3e-08 33.0 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase RINGv PF12906.7 KIY65130.1 - 1.7e-12 47.2 3.8 2.6e-12 46.6 3.8 1.3 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 KIY65130.1 - 0.0031 17.8 6.2 0.0047 17.2 6.2 1.3 1 0 0 1 1 1 1 Ring finger domain PHD PF00628.29 KIY65130.1 - 0.35 10.8 3.9 0.56 10.1 3.9 1.3 1 0 0 1 1 1 0 PHD-finger Mito_carr PF00153.27 KIY65131.1 - 1.1e-34 118.3 0.1 2.3e-17 62.7 0.1 2.7 3 0 0 3 3 3 2 Mitochondrial carrier protein RNase_T PF00929.24 KIY65132.1 - 4.9e-07 30.5 0.0 5.6e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Exonuclease DUF3025 PF11227.8 KIY65132.1 - 0.0025 17.6 0.0 0.0035 17.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3025) Sulfotransfer_4 PF17784.1 KIY65132.1 - 0.039 13.8 0.1 0.69 9.7 0.0 2.0 2 0 0 2 2 2 0 Sulfotransferase domain PPR_2 PF13041.6 KIY65134.1 - 5.2e-06 26.5 0.0 9.8e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 PPR repeat family TPR_19 PF14559.6 KIY65134.1 - 0.028 14.9 0.8 0.028 14.9 0.8 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat FAST_1 PF06743.15 KIY65134.1 - 0.043 13.8 0.0 0.14 12.1 0.0 1.8 1 0 0 1 1 1 0 FAST kinase-like protein, subdomain 1 Cut8 PF08559.10 KIY65135.1 - 1.3e-12 47.8 0.0 1.2e-11 44.7 0.0 2.2 1 1 0 1 1 1 1 Cut8, nuclear proteasome tether protein MARVEL PF01284.23 KIY65137.1 - 0.012 15.7 8.4 0.06 13.4 8.4 1.9 1 1 0 1 1 1 0 Membrane-associating domain FtsX PF02687.21 KIY65137.1 - 0.1 13.1 5.5 0.74 10.3 5.5 2.2 1 1 0 1 1 1 0 FtsX-like permease family DUF996 PF06195.13 KIY65137.1 - 0.18 12.1 6.8 2.2 8.5 6.8 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF996) Rrp15p PF07890.12 KIY65138.1 - 6.8e-25 87.9 13.1 1.9e-24 86.5 13.1 1.8 1 1 0 1 1 1 1 Rrp15p Ndc1_Nup PF09531.10 KIY65138.1 - 1.6 7.3 3.1 1.9 7.1 3.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup MRP-S28 PF10213.9 KIY65139.1 - 2.9e-27 95.6 0.0 4.7e-27 94.9 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein DUF866 PF05907.13 KIY65140.1 - 1.1e-58 197.5 0.4 1.3e-58 197.4 0.4 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Zn_ribbon_SprT PF17283.2 KIY65140.1 - 0.01 15.7 1.1 0.021 14.7 1.1 1.5 1 1 0 1 1 1 0 SprT-like zinc ribbon domain EPF PF17181.4 KIY65140.1 - 0.13 12.3 1.9 0.21 11.6 1.9 1.4 1 0 0 1 1 1 0 Epidermal patterning factor proteins DUF4379 PF14311.6 KIY65140.1 - 0.47 10.8 4.4 1.5 9.3 2.5 2.3 1 1 1 2 2 2 0 Probable Zinc-ribbon domain HalOD2 PF18547.1 KIY65140.1 - 0.48 10.4 3.6 2.3 8.2 0.1 2.9 3 0 0 3 3 3 0 Halobacterial output domain 2 DIL PF01843.19 KIY65141.1 - 1e-25 90.0 2.9 1.1e-25 89.9 1.5 1.8 2 0 0 2 2 2 1 DIL domain Ank_5 PF13857.6 KIY65141.1 - 6.1e-07 29.6 0.0 2.8e-06 27.5 0.0 2.2 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KIY65141.1 - 2.1e-06 28.2 0.0 8.2e-06 26.3 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KIY65141.1 - 2.2e-06 28.1 0.0 3.4e-05 24.3 0.0 2.9 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIY65141.1 - 3.4e-05 23.9 0.0 0.0013 19.1 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 KIY65141.1 - 7.2e-05 23.1 0.3 0.036 14.5 0.0 3.9 4 0 0 4 4 4 1 Ankyrin repeat MARVEL PF01284.23 KIY65142.1 - 0.00039 20.5 6.7 0.00056 20.0 6.7 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF1270 PF06900.11 KIY65142.1 - 0.058 13.8 1.3 0.058 13.8 1.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1270) PrgI PF12666.7 KIY65142.1 - 4.1 8.2 7.9 0.2 12.4 1.1 2.2 3 0 0 3 3 3 0 PrgI family protein p450 PF00067.22 KIY65143.1 - 1.6e-51 175.6 0.0 1.8e-51 175.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CLTH PF10607.9 KIY65144.1 - 6.7e-32 110.4 0.0 8.9e-32 110.0 0.0 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 KIY65144.1 - 6.9e-11 41.7 0.2 1.4e-10 40.7 0.2 1.6 1 0 0 1 1 1 1 LisH FPRL1_inhibitor PF16104.5 KIY65144.1 - 0.022 14.9 0.0 0.062 13.4 0.0 1.7 2 0 0 2 2 2 0 Formyl peptide receptor-like 1 inhibitory protein GntR PF00392.21 KIY65144.1 - 0.03 14.0 1.0 0.14 11.9 0.1 2.2 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family TINF2_N PF14973.6 KIY65144.1 - 0.068 13.5 0.1 0.15 12.4 0.1 1.6 1 0 0 1 1 1 0 TERF1-interacting nuclear factor 2 N-terminus CN_hydrolase PF00795.22 KIY65145.1 - 2e-52 178.1 0.0 2.2e-52 178.0 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase SR-25 PF10500.9 KIY65146.1 - 0.022 14.4 13.3 0.026 14.1 9.7 2.0 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein ORC6 PF05460.13 KIY65146.1 - 0.028 13.7 4.6 0.034 13.4 4.6 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) PAP1 PF08601.10 KIY65146.1 - 0.032 14.0 4.7 0.038 13.7 4.7 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 Macoilin PF09726.9 KIY65146.1 - 0.08 11.5 3.7 0.091 11.3 3.7 1.0 1 0 0 1 1 1 0 Macoilin family DUF2859 PF11072.8 KIY65146.1 - 0.16 11.7 1.4 11 5.7 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2859) Corona_nucleoca PF00937.18 KIY65146.1 - 0.59 9.1 8.8 0.74 8.8 8.8 1.0 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein CCDC106 PF15794.5 KIY65146.1 - 0.86 9.3 7.7 0.15 11.7 2.4 1.9 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 Septin PF00735.18 KIY65147.1 - 5.8e-120 399.8 0.0 5.8e-120 399.8 0.0 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 KIY65147.1 - 1.7e-07 31.3 0.5 5e-07 29.8 0.0 2.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KIY65147.1 - 0.0002 21.0 4.0 0.0071 15.9 0.0 3.4 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KIY65147.1 - 0.00029 20.8 0.7 0.00029 20.8 0.7 3.3 3 1 0 3 3 3 1 RsgA GTPase AAA_22 PF13401.6 KIY65147.1 - 0.00047 20.4 0.1 0.0046 17.2 0.0 2.6 2 2 0 2 2 2 1 AAA domain Ras PF00071.22 KIY65147.1 - 0.0023 17.5 0.0 0.028 14.0 0.0 2.5 2 0 0 2 2 2 1 Ras family Dynamin_N PF00350.23 KIY65147.1 - 0.0024 17.9 4.1 1.5 8.8 0.0 3.3 3 0 0 3 3 3 2 Dynamin family AAA_16 PF13191.6 KIY65147.1 - 0.0049 17.3 0.0 0.017 15.5 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 KIY65147.1 - 0.0057 16.4 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AIG1 PF04548.16 KIY65147.1 - 0.0063 15.9 0.6 0.017 14.4 0.0 2.1 2 0 0 2 2 2 1 AIG1 family Roc PF08477.13 KIY65147.1 - 0.019 15.2 0.0 0.066 13.4 0.0 2.0 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 KIY65147.1 - 0.023 15.2 6.9 0.043 14.3 0.9 2.8 2 1 0 2 2 2 0 ABC transporter Sec1 PF00995.23 KIY65147.1 - 0.12 11.5 1.2 0.25 10.5 0.1 1.8 2 0 0 2 2 2 0 Sec1 family Exonuc_VII_L PF02601.15 KIY65147.1 - 0.19 11.2 3.5 0.34 10.4 3.5 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit AAA_23 PF13476.6 KIY65147.1 - 0.64 10.5 9.8 42 4.5 9.8 2.3 1 1 0 1 1 1 0 AAA domain DUF87 PF01935.17 KIY65147.1 - 0.76 9.8 3.4 5 7.2 0.1 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain Strep_SA_rep PF06696.11 KIY65147.1 - 2.9 8.0 12.6 0.27 11.3 3.7 2.6 1 1 1 2 2 2 0 Streptococcal surface antigen repeat DUF4407 PF14362.6 KIY65147.1 - 3.3 7.0 8.3 0.25 10.6 3.5 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) ATP_bind_1 PF03029.17 KIY65147.1 - 4.1 7.1 8.4 9.7 5.9 0.1 3.4 3 1 0 3 3 3 0 Conserved hypothetical ATP binding protein p450 PF00067.22 KIY65149.1 - 2e-35 122.5 0.1 5.5e-34 117.7 0.0 2.5 2 1 0 2 2 2 2 Cytochrome P450 Abhydrolase_6 PF12697.7 KIY65150.1 - 9.9e-11 42.7 4.3 1.8e-10 41.8 4.3 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KIY65150.1 - 1.6e-09 37.8 0.0 1.1e-05 25.2 0.2 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIY65150.1 - 5e-06 25.9 0.1 0.00018 20.8 0.0 2.7 2 1 0 2 2 2 1 Serine aminopeptidase, S33 DUF1057 PF06342.12 KIY65150.1 - 0.00018 20.6 0.0 0.00025 20.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_4 PF08386.10 KIY65150.1 - 0.0018 18.4 0.0 0.0057 16.7 0.0 1.8 2 0 0 2 2 2 1 TAP-like protein DUF2048 PF09752.9 KIY65150.1 - 0.021 14.0 0.0 0.093 11.8 0.0 1.9 2 0 0 2 2 2 0 Abhydrolase domain containing 18 Ser_hydrolase PF06821.13 KIY65150.1 - 0.12 12.2 0.5 8.9 6.1 0.0 3.3 3 1 0 3 3 3 0 Serine hydrolase DUF202 PF02656.15 KIY65151.1 - 2.5e-13 50.2 1.9 2.5e-13 50.2 1.9 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) FixQ PF05545.11 KIY65151.1 - 8.8 6.4 7.8 0.37 10.8 1.4 2.0 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ Pkinase_fungal PF17667.1 KIY65152.1 - 1.4e-22 80.1 1.2 3.9e-14 52.3 0.1 3.0 1 1 1 2 2 2 2 Fungal protein kinase Kdo PF06293.14 KIY65152.1 - 0.013 14.8 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KIY65152.1 - 0.013 14.4 0.0 0.02 13.9 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 KIY65152.1 - 0.013 15.4 0.3 0.047 13.6 0.3 2.0 1 1 0 1 1 1 0 Phosphotransferase enzyme family DUF440 PF04269.12 KIY65152.1 - 0.12 12.7 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF440 LRR_4 PF12799.7 KIY65155.1 - 0.15 12.5 2.0 3.4 8.2 0.1 3.5 2 1 3 5 5 5 0 Leucine Rich repeats (2 copies) SQS_PSY PF00494.19 KIY65156.1 - 9.1e-35 120.4 0.0 1.3e-34 119.9 0.0 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase VQ PF05678.14 KIY65156.1 - 0.12 11.8 0.0 0.25 10.8 0.0 1.5 1 0 0 1 1 1 0 VQ motif DNA_pol3_delta2 PF13177.6 KIY65157.1 - 6.2e-14 52.1 0.1 1e-13 51.4 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 KIY65157.1 - 1.3e-06 28.8 0.5 3.6e-06 27.4 0.5 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 KIY65157.1 - 0.00048 20.5 0.7 0.0013 19.1 0.0 2.1 3 0 0 3 3 3 1 Replication factor C C-terminal domain Rad17 PF03215.15 KIY65157.1 - 0.0051 16.7 0.0 0.012 15.5 0.0 1.8 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 KIY65157.1 - 0.013 15.7 0.8 0.085 13.1 0.8 2.3 1 1 0 1 1 1 0 AAA domain DNA_pol3_delta PF06144.13 KIY65157.1 - 0.014 15.2 0.0 0.027 14.3 0.0 1.5 1 1 0 1 1 1 0 DNA polymerase III, delta subunit AAA_16 PF13191.6 KIY65157.1 - 0.015 15.7 0.1 0.048 14.0 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain TSC21 PF15217.6 KIY65157.1 - 0.039 13.9 0.1 0.067 13.1 0.1 1.3 1 0 0 1 1 1 0 TSC21 family RuvB_N PF05496.12 KIY65157.1 - 0.12 12.2 0.0 5.3 6.8 0.0 2.4 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Herpes_TK_C PF08465.10 KIY65157.1 - 0.13 12.0 0.0 0.32 10.8 0.0 1.7 1 0 0 1 1 1 0 Thymidine kinase from Herpesvirus C-terminal AAA_33 PF13671.6 KIY65157.1 - 0.14 12.3 0.1 0.75 9.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain Phyto-Amp PF15438.6 KIY65157.1 - 0.18 11.7 0.1 0.26 11.1 0.1 1.2 1 0 0 1 1 1 0 Antigenic membrane protein of phytoplasma Zip PF02535.22 KIY65158.1 - 1.6e-44 152.5 19.2 2.8e-42 145.2 19.2 2.2 1 1 0 1 1 1 1 ZIP Zinc transporter NUDIX PF00293.28 KIY65159.1 - 6.8e-13 48.8 0.2 9.4e-13 48.3 0.2 1.2 1 0 0 1 1 1 1 NUDIX domain BaffR-Tall_bind PF09256.10 KIY65160.1 - 0.13 12.0 0.1 0.26 11.1 0.1 1.5 1 0 0 1 1 1 0 BAFF-R, TALL-1 binding CFC PF09443.10 KIY65160.1 - 0.33 10.8 4.7 0.16 11.8 0.9 2.2 2 0 0 2 2 2 0 Cripto_Frl-1_Cryptic (CFC) TEA PF01285.18 KIY65161.1 - 5.5e-20 71.2 0.0 9.9e-20 70.4 0.0 1.4 1 0 0 1 1 1 1 TEA/ATTS domain EC042_2821 PF18740.1 KIY65161.1 - 0.12 12.2 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 EC042_2821-lke REase ATP_synt_H PF05493.13 KIY65162.1 - 1.4e-20 73.5 5.0 1.6e-20 73.3 5.0 1.0 1 0 0 1 1 1 1 ATP synthase subunit H DUF4131 PF13567.6 KIY65162.1 - 0.0027 17.4 1.4 0.0028 17.3 1.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4131) YibE_F PF07907.11 KIY65162.1 - 0.027 13.9 1.7 0.03 13.8 1.7 1.0 1 0 0 1 1 1 0 YibE/F-like protein SLATT_1 PF18181.1 KIY65162.1 - 0.067 13.1 0.7 0.077 12.9 0.7 1.1 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 S_4TM PF18159.1 KIY65162.1 - 0.12 11.6 1.9 0.14 11.5 1.9 1.0 1 0 0 1 1 1 0 SMODS-associating 4TM effector domain Phage_holin_3_6 PF07332.11 KIY65162.1 - 0.24 11.4 4.1 0.29 11.2 4.1 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Methyltransf_23 PF13489.6 KIY65163.1 - 0.0012 18.7 0.0 0.0065 16.3 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIY65163.1 - 0.19 12.5 0.0 16 6.3 0.0 2.8 2 1 0 2 2 2 0 Methyltransferase domain HD PF01966.22 KIY65164.1 - 7.5e-06 26.2 0.2 2.9e-05 24.3 0.2 1.9 1 1 0 1 1 1 1 HD domain DUF3421 PF11901.8 KIY65165.1 - 1.1e-30 106.0 0.0 2.4e-30 104.8 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3421) SR-25 PF10500.9 KIY65165.1 - 0.0011 18.6 15.6 0.0014 18.3 15.6 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Tim54 PF11711.8 KIY65165.1 - 0.32 9.7 2.5 0.4 9.4 2.5 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 TFIIF_alpha PF05793.12 KIY65165.1 - 1.9 7.0 16.7 2.4 6.6 16.7 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Med19 PF10278.9 KIY65165.1 - 3.4 7.6 21.7 5.4 6.9 21.7 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 RhoGAP PF00620.27 KIY65166.1 - 6.5e-42 142.9 0.0 4.9e-41 140.1 0.0 2.1 2 0 0 2 2 2 1 RhoGAP domain RasGEF PF00617.19 KIY65166.1 - 5.2e-12 46.3 0.0 6.7e-11 42.7 0.0 2.5 2 0 0 2 2 2 1 RasGEF domain PH_9 PF15410.6 KIY65166.1 - 0.0011 19.4 0.0 0.0025 18.2 0.0 1.6 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KIY65166.1 - 0.0037 17.8 0.0 0.0077 16.7 0.0 1.5 1 0 0 1 1 1 1 PH domain RasGEF_N PF00618.20 KIY65166.1 - 0.0098 16.1 0.2 0.3 11.3 0.1 3.3 2 1 0 2 2 2 1 RasGEF N-terminal motif KilA-N PF04383.13 KIY65167.1 - 0.0024 17.7 0.0 0.006 16.4 0.0 1.6 1 1 0 1 1 1 1 KilA-N domain SOG2 PF10428.9 KIY65167.1 - 0.037 13.2 6.3 0.044 13.0 6.3 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein TFIIF_alpha PF05793.12 KIY65167.1 - 9.9 4.6 8.9 13 4.2 8.9 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Acetyltransf_3 PF13302.7 KIY65168.1 - 1.1e-16 61.7 0.0 1.6e-16 61.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIY65168.1 - 5.7e-11 42.7 0.0 7.6e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 KIY65168.1 - 2e-08 34.1 0.0 3.2e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KIY65168.1 - 4.2e-05 23.7 0.0 0.00011 22.4 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KIY65168.1 - 6.1e-05 23.4 0.0 8.8e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KIY65168.1 - 0.00054 19.9 0.0 0.00083 19.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIY65168.1 - 0.022 14.7 0.0 0.042 13.8 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Mito_carr PF00153.27 KIY65169.1 - 1.2e-64 214.3 0.9 1.6e-22 79.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein WD40 PF00400.32 KIY65170.1 - 1.3e-41 139.8 18.9 3.8e-08 33.8 0.5 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.8 KIY65170.1 - 0.0099 14.6 1.4 3.6 6.1 0.4 3.6 1 1 2 3 3 3 1 Nucleoporin Nup120/160 CbiG_N PF11760.8 KIY65170.1 - 0.12 12.4 0.1 7.5 6.6 0.0 2.9 2 1 1 3 3 3 0 Cobalamin synthesis G N-terminal Staphostatin_B PF09023.10 KIY65172.1 - 0.17 11.9 2.2 0.21 11.7 2.2 1.2 1 0 0 1 1 1 0 Staphostatin B LsmAD PF06741.13 KIY65174.1 - 1.4e-27 96.0 1.4 1.4e-27 96.0 1.4 2.4 2 0 0 2 2 2 1 LsmAD domain SM-ATX PF14438.6 KIY65174.1 - 0.00037 20.6 0.1 0.00093 19.3 0.1 1.6 1 0 0 1 1 1 1 Ataxin 2 SM domain SARAF PF06682.12 KIY65174.1 - 1.3 8.6 6.2 3.3 7.3 6.2 1.7 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis PepSY_TM PF03929.16 KIY65174.1 - 2.7 7.6 4.8 13 5.4 4.8 2.1 1 0 0 1 1 1 0 PepSY-associated TM region PseudoU_synth_1 PF01416.20 KIY65175.1 - 4.3e-24 85.1 0.0 1.8e-23 83.1 0.0 2.0 2 0 0 2 2 2 1 tRNA pseudouridine synthase Pkinase PF00069.25 KIY65176.1 - 8e-31 107.4 0.0 4.8e-30 104.8 0.0 2.1 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY65176.1 - 1e-19 70.9 0.0 3.3e-19 69.2 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY65176.1 - 0.016 14.5 0.0 0.049 13.0 0.0 1.6 1 1 0 1 1 1 0 Kinase-like PBD PF00786.28 KIY65177.1 - 0.036 14.4 0.1 0.081 13.3 0.1 1.5 1 0 0 1 1 1 0 P21-Rho-binding domain Lipase_GDSL_2 PF13472.6 KIY65178.1 - 0.00015 22.2 2.6 0.00027 21.4 2.6 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KIY65178.1 - 0.061 13.3 0.0 0.19 11.6 0.0 2.0 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase RNA_pol_I_A49 PF06870.12 KIY65180.1 - 1e-98 330.7 0.1 1.2e-98 330.5 0.1 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor DUF3806 PF12713.7 KIY65180.1 - 0.012 15.3 0.0 0.032 14.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3806) BP28CT PF08146.12 KIY65181.1 - 2e-19 70.0 1.3 5.9e-19 68.5 1.3 1.9 1 0 0 1 1 1 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 KIY65181.1 - 1.5e-12 47.9 5.1 4e-12 46.5 0.8 4.1 3 0 0 3 3 3 1 U3 small nucleolar RNA-associated protein 10 TetR_C_18 PF17923.1 KIY65181.1 - 0.12 12.9 1.3 19 5.8 0.1 3.0 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain HEAT PF02985.22 KIY65181.1 - 2.6 8.6 8.5 15 6.2 0.2 4.9 4 0 0 4 4 4 0 HEAT repeat Aldo_ket_red PF00248.21 KIY65182.1 - 2.4e-43 148.4 0.2 2.3e-41 141.9 0.2 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Glyco_hydro_15 PF00723.21 KIY65183.1 - 1.7e-97 327.0 0.2 1.9e-97 326.9 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 RdRP PF05183.12 KIY65184.1 - 5.8e-158 527.2 0.0 7.1e-158 526.9 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Metallophos PF00149.28 KIY65185.1 - 7.4e-11 42.9 1.3 1.7e-10 41.7 1.3 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KIY65185.1 - 0.00035 20.8 0.2 0.017 15.3 0.2 2.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Membr_traf_MHD PF10540.9 KIY65186.1 - 2.4e-25 89.5 0.2 1.5e-12 47.9 0.0 2.8 1 1 1 2 2 2 2 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.30 KIY65186.1 - 5.3e-09 36.3 0.0 2.8e-08 34.0 0.0 2.2 2 0 0 2 2 2 1 C2 domain DUF810 PF05664.11 KIY65186.1 - 8.7e-06 24.6 3.0 1.1e-05 24.2 0.1 2.1 2 0 0 2 2 2 1 Plant family of unknown function (DUF810) RdRP PF05183.12 KIY65187.1 - 4.7e-162 540.7 0.0 6e-162 540.3 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase ATP_sub_h PF10775.9 KIY65189.1 - 0.031 14.2 1.0 0.052 13.5 1.0 1.4 1 0 0 1 1 1 0 ATP synthase complex subunit h zf-C2H2_4 PF13894.6 KIY65190.1 - 0.00033 21.2 13.3 0.021 15.6 1.0 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KIY65190.1 - 0.00043 20.6 13.1 0.02 15.3 1.4 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KIY65190.1 - 0.67 10.5 11.4 6.4 7.4 0.8 3.4 2 1 1 3 3 3 0 Zinc-finger double domain p450 PF00067.22 KIY65192.1 - 1.7e-74 251.3 0.0 2.1e-74 251.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Terpene_synth_C PF03936.16 KIY65193.1 - 5e-06 26.1 0.0 7e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Cu-oxidase_2 PF07731.14 KIY65195.1 - 1.3e-28 99.4 3.0 1.3e-19 70.3 0.5 4.2 4 0 0 4 4 4 3 Multicopper oxidase Cu-oxidase_3 PF07732.15 KIY65195.1 - 7.7e-27 93.7 0.0 2e-26 92.3 0.0 1.8 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase PF00394.22 KIY65195.1 - 1.5e-10 41.5 0.0 3.5e-10 40.2 0.0 1.7 1 1 0 1 1 1 1 Multicopper oxidase PGI PF00342.19 KIY65196.1 - 1.1e-234 779.6 0.5 1.2e-234 779.4 0.5 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase Glyco_hydro_6 PF01341.17 KIY65197.1 - 7e-100 334.7 0.8 8.9e-100 334.3 0.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 Glyco_hydro_6 PF01341.17 KIY65198.1 - 1.4e-97 327.1 0.6 1.8e-97 326.8 0.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 CBM_1 PF00734.18 KIY65198.1 - 3.7e-11 42.8 10.9 9e-11 41.5 10.9 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain Metallophos PF00149.28 KIY65199.1 - 1.2e-10 42.3 0.0 2.5e-10 41.2 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase FBPase_2 PF06874.11 KIY65199.1 - 0.0014 17.0 0.2 0.046 12.0 0.0 2.2 2 0 0 2 2 2 2 Firmicute fructose-1,6-bisphosphatase DnaJ PF00226.31 KIY65200.1 - 5.8e-16 58.4 1.2 5.8e-16 58.4 1.2 2.0 2 0 0 2 2 2 1 DnaJ domain Pectate_lyase_3 PF12708.7 KIY65201.1 - 1.6e-92 309.2 12.9 2.3e-77 259.7 6.4 2.7 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 KIY65201.1 - 4.7e-07 29.4 0.6 0.035 13.8 0.0 2.9 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Epimerase PF01370.21 KIY65202.1 - 0.0078 15.7 0.0 0.012 15.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_2 PF03446.15 KIY65203.1 - 3.9e-36 124.6 0.4 6.5e-36 123.9 0.4 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KIY65203.1 - 7.1e-30 103.8 0.0 2.5e-29 102.0 0.0 1.9 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 KIY65203.1 - 0.01 16.4 0.0 0.02 15.5 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.12 KIY65203.1 - 0.044 13.4 0.0 0.28 10.7 0.0 2.3 2 1 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Cytochrom_B561 PF03188.16 KIY65205.1 - 7.1e-13 48.9 7.3 9.5e-13 48.5 6.7 1.5 1 1 0 1 1 1 1 Eukaryotic cytochrome b561 Sdh_cyt PF01127.22 KIY65205.1 - 0.046 13.8 0.4 0.046 13.8 0.4 2.9 2 1 1 3 3 3 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF4079 PF13301.6 KIY65205.1 - 4.2 7.5 8.4 8.6 6.5 6.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF4079) MAT1 PF06391.13 KIY65207.1 - 1.6e-54 184.8 16.1 2.4e-54 184.3 16.1 1.2 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 KIY65207.1 - 1.5e-21 76.0 8.1 2.6e-21 75.2 8.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIY65207.1 - 4.4e-05 23.4 7.0 0.00017 21.5 7.2 1.8 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KIY65207.1 - 5e-05 23.1 6.1 0.0001 22.1 6.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KIY65207.1 - 7.1e-05 22.6 6.7 0.00014 21.7 6.7 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIY65207.1 - 9.2e-05 22.7 6.7 0.00016 21.9 6.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KIY65207.1 - 0.00013 21.7 7.7 0.0003 20.5 7.8 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KIY65207.1 - 0.0023 17.9 2.4 0.0023 17.9 2.4 2.2 1 1 1 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KIY65207.1 - 0.011 15.5 9.4 0.21 11.5 9.7 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KIY65207.1 - 0.046 14.0 2.4 0.1 12.9 2.4 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_4 PF14570.6 KIY65207.1 - 0.09 12.6 4.7 0.64 9.9 2.0 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain MCD_N PF17408.2 KIY65207.1 - 0.32 11.1 2.2 1.9 8.7 1.8 2.2 2 0 0 2 2 2 0 Malonyl-CoA decarboxylase N-terminal domain DUF3797 PF12677.7 KIY65207.1 - 1.5 8.8 7.2 0.24 11.3 0.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3797) zf-C3HC4_4 PF15227.6 KIY65207.1 - 1.8 8.8 7.7 18 5.6 8.3 2.3 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING Usp PF00582.26 KIY65207.1 - 3.2 8.3 6.3 5.5 7.5 6.3 1.3 1 0 0 1 1 1 0 Universal stress protein family WD40 PF00400.32 KIY65208.1 - 8.2e-21 73.9 6.1 1.3e-08 35.3 0.1 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat Alpha-2-MRAP_C PF06401.11 KIY65208.1 - 0.027 14.4 0.3 0.05 13.6 0.0 1.5 2 0 0 2 2 2 0 Alpha-2-macroglobulin RAP, C-terminal domain Nup160 PF11715.8 KIY65208.1 - 0.036 12.7 1.2 0.74 8.4 0.5 2.6 2 1 0 2 2 2 0 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KIY65208.1 - 0.051 12.3 0.2 4.1 6.0 0.0 2.4 2 1 1 3 3 3 0 Nup133 N terminal like ANAPC4_WD40 PF12894.7 KIY65208.1 - 0.052 13.9 0.1 0.5 10.7 0.0 2.5 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Baculo_E66 PF04850.12 KIY65208.1 - 0.22 10.3 0.0 0.39 9.5 0.0 1.3 1 0 0 1 1 1 0 Baculovirus E66 occlusion-derived virus envelope protein ATP_bind_1 PF03029.17 KIY65209.1 - 4.1e-73 246.1 0.0 4.9e-73 245.9 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_33 PF13671.6 KIY65209.1 - 0.075 13.2 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.10 KIY65209.1 - 0.17 11.3 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Helicase_C PF00271.31 KIY65210.1 - 7.1e-18 65.0 0.0 1e-16 61.2 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KIY65210.1 - 3.3e-17 62.8 0.0 1e-16 61.2 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 KIY65210.1 - 3.1e-09 37.4 0.1 1.3e-08 35.4 0.1 2.3 1 0 0 1 1 1 1 RecQ zinc-binding ResIII PF04851.15 KIY65210.1 - 0.00028 20.9 0.0 0.00095 19.2 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KIY65210.1 - 0.081 13.2 0.9 0.59 10.4 0.9 2.3 1 1 0 1 1 1 0 AAA domain RQC PF09382.10 KIY65210.1 - 0.083 12.7 0.3 0.5 10.2 0.1 2.3 2 0 0 2 2 2 0 RQC domain ZapB PF06005.12 KIY65210.1 - 1.1 9.7 5.8 0.74 10.3 2.5 2.3 2 0 0 2 2 2 0 Cell division protein ZapB DivIC PF04977.15 KIY65210.1 - 1.3 8.9 4.3 4.4 7.2 4.3 1.9 1 0 0 1 1 1 0 Septum formation initiator Sec7 PF01369.20 KIY65211.1 - 2.9e-65 219.4 0.1 5.1e-65 218.6 0.1 1.4 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 KIY65211.1 - 2.5e-19 69.7 0.0 7.9e-18 64.9 0.0 2.7 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 KIY65211.1 - 0.0019 18.0 1.1 0.81 9.6 0.0 4.4 4 0 0 4 4 4 1 Domain of unknown function (DUF1981) F-box-like PF12937.7 KIY65212.1 - 0.0002 21.2 6.4 0.00036 20.4 4.6 2.2 2 1 0 2 2 2 1 F-box-like F-box PF00646.33 KIY65212.1 - 0.043 13.7 0.7 0.18 11.7 0.7 2.0 1 1 0 1 1 1 0 F-box domain OAS1_C PF10421.9 KIY65212.1 - 0.044 13.3 0.6 0.094 12.2 0.1 1.7 1 1 1 2 2 2 0 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus F-box-like PF12937.7 KIY65213.1 - 1.1e-11 44.4 1.5 3.5e-11 42.8 1.5 1.9 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KIY65214.1 - 9.4e-10 38.2 1.0 2.3e-09 37.0 1.0 1.7 1 0 0 1 1 1 1 F-box-like Bestrophin PF01062.21 KIY65215.1 - 1.5e-35 123.1 0.1 1.2e-20 74.1 0.0 2.2 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel DUF4229 PF14012.6 KIY65215.1 - 0.38 10.9 3.0 0.89 9.7 3.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) Porin_3 PF01459.22 KIY65216.1 - 1.1e-66 225.1 6.2 1.2e-66 225.0 6.2 1.0 1 0 0 1 1 1 1 Eukaryotic porin SpoIIP PF07454.11 KIY65216.1 - 0.025 14.0 0.1 0.04 13.4 0.1 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) F-box-like PF12937.7 KIY65218.1 - 8.5e-07 28.8 0.2 1.7e-06 27.8 0.2 1.5 1 0 0 1 1 1 1 F-box-like DUF4327 PF14217.6 KIY65218.1 - 0.028 14.5 0.6 0.063 13.4 0.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4327) F-box PF00646.33 KIY65218.1 - 0.031 14.2 0.3 0.065 13.1 0.3 1.6 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 KIY65220.1 - 1e-06 28.5 0.1 2.4e-06 27.3 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY65220.1 - 0.011 15.5 1.0 0.029 14.2 0.0 2.1 2 0 0 2 2 2 0 F-box domain F-box PF00646.33 KIY65221.1 - 0.0043 16.9 0.5 0.015 15.1 0.5 2.0 1 0 0 1 1 1 1 F-box domain DUF3760 PF12586.8 KIY65221.1 - 0.048 13.9 2.2 0.12 12.5 2.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3760) F-box-like PF12937.7 KIY65222.1 - 0.0012 18.7 0.2 0.0012 18.7 0.2 2.2 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 KIY65222.1 - 0.0034 17.2 0.1 0.013 15.3 0.1 2.1 1 0 0 1 1 1 1 F-box domain LRR_8 PF13855.6 KIY65222.1 - 0.026 14.3 2.4 4.4 7.1 1.8 3.0 3 0 0 3 3 3 0 Leucine rich repeat F-box-like PF12937.7 KIY65223.1 - 2.6e-07 30.4 2.0 2.6e-07 30.4 2.0 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIY65223.1 - 0.04 13.8 7.5 5 7.1 0.2 4.1 4 0 0 4 4 4 0 F-box domain THOC7 PF05615.13 KIY65223.1 - 0.044 14.1 0.3 0.092 13.0 0.3 1.4 1 0 0 1 1 1 0 Tho complex subunit 7 F-box-like PF12937.7 KIY65224.1 - 1e-06 28.5 1.9 1e-06 28.5 1.9 2.2 2 0 0 2 2 2 1 F-box-like PPP4R2 PF09184.11 KIY65224.1 - 1.2 8.7 23.2 2.3 7.8 23.2 1.4 1 0 0 1 1 1 0 PPP4R2 F-box PF00646.33 KIY65224.1 - 1.4 8.9 5.2 32 4.6 1.3 3.4 2 1 0 2 2 2 0 F-box domain ADH_zinc_N PF00107.26 KIY65225.1 - 3.8e-12 46.3 0.0 6.7e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIY65225.1 - 1e-09 38.3 0.0 4.1e-09 36.3 0.0 1.9 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KIY65225.1 - 0.0021 19.1 0.0 0.0039 18.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Acetyltransf_3 PF13302.7 KIY65226.1 - 9.4e-18 65.2 0.0 1.1e-17 65.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIY65226.1 - 1e-06 29.0 0.0 1.5e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 KIY65226.1 - 0.0041 16.8 0.0 0.0061 16.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Arb2 PF09757.9 KIY65226.1 - 0.031 13.4 0.0 0.046 12.8 0.0 1.2 1 0 0 1 1 1 0 Arb2 domain FR47 PF08445.10 KIY65226.1 - 0.094 12.7 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein Peptidase_C14 PF00656.22 KIY65227.1 - 3.9e-39 135.1 0.0 5.1e-39 134.7 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.6 KIY65227.1 - 0.0018 18.3 0.0 0.0077 16.2 0.0 2.0 2 1 0 2 2 2 1 Raptor N-terminal CASPase like domain Salt_tol_Pase PF09506.10 KIY65227.1 - 0.075 11.8 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 Glucosylglycerol-phosphate phosphatase (Salt_tol_Pase) Na_Ca_ex PF01699.24 KIY65228.1 - 2.4e-16 60.1 36.4 2.5e-12 47.0 13.3 3.5 4 1 0 4 4 4 2 Sodium/calcium exchanger protein YccF PF03733.13 KIY65228.1 - 6.1e-14 52.5 11.8 6.1e-14 52.5 11.8 3.8 3 0 0 3 3 3 1 Inner membrane component domain BUD22 PF09073.10 KIY65228.1 - 0.0048 16.3 0.0 0.01 15.2 0.0 1.5 1 1 0 1 1 1 1 BUD22 Oxidored_FMN PF00724.20 KIY65229.1 - 7.9e-92 308.1 0.0 9e-92 307.9 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Osmo_CC PF08946.10 KIY65230.1 - 2.8 8.3 5.1 1.1 9.6 1.0 2.1 2 0 0 2 2 2 0 Osmosensory transporter coiled coil Zn_clus PF00172.18 KIY65231.1 - 4.5e-08 33.1 9.2 7.1e-08 32.4 9.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KIY65231.1 - 0.03 13.3 0.1 0.047 12.7 0.1 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain ArsB PF02040.15 KIY65232.1 - 1.6e-11 44.2 24.0 1.1e-08 34.8 12.9 2.1 2 0 0 2 2 2 2 Arsenical pump membrane protein His_Phos_2 PF00328.22 KIY65234.1 - 1.4e-06 27.9 0.1 0.00012 21.5 0.0 2.4 1 1 2 3 3 3 2 Histidine phosphatase superfamily (branch 2) DUF4453 PF14627.6 KIY65234.1 - 0.085 13.0 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4453) Pyr_redox_dim PF02852.22 KIY65240.1 - 0.15 12.3 0.0 0.53 10.6 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Integrase_H2C2 PF17921.1 KIY65241.1 - 0.038 14.1 0.1 0.077 13.1 0.1 1.5 1 0 0 1 1 1 0 Integrase zinc binding domain DUF2205 PF10224.9 KIY65243.1 - 1.5e-05 24.9 3.5 1.5e-05 24.9 3.5 2.3 1 1 1 2 2 2 1 Short coiled-coil protein zf-GRF PF06839.12 KIY65243.1 - 0.00017 21.6 0.7 0.00027 21.0 0.7 1.3 1 0 0 1 1 1 1 GRF zinc finger ATG16 PF08614.11 KIY65243.1 - 0.00017 21.9 16.7 0.0021 18.3 17.0 2.1 1 1 0 1 1 1 1 Autophagy protein 16 (ATG16) DUF812 PF05667.11 KIY65243.1 - 0.0008 18.4 8.3 0.001 18.1 8.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Jnk-SapK_ap_N PF09744.9 KIY65243.1 - 0.0021 18.3 15.4 0.0033 17.7 15.4 1.4 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 Cnn_1N PF07989.11 KIY65243.1 - 0.0028 17.8 14.3 0.049 13.8 8.4 2.3 2 0 0 2 2 2 1 Centrosomin N-terminal motif 1 BRE1 PF08647.11 KIY65243.1 - 0.005 16.9 11.9 0.0091 16.0 11.9 1.4 1 0 0 1 1 1 1 BRE1 E3 ubiquitin ligase CALCOCO1 PF07888.11 KIY65243.1 - 0.01 14.7 20.4 0.061 12.2 20.5 1.8 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like GAS PF13851.6 KIY65243.1 - 0.017 14.5 17.2 0.023 14.1 17.2 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding EzrA PF06160.12 KIY65243.1 - 0.022 13.0 12.2 0.029 12.6 12.2 1.0 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DUF2937 PF11157.8 KIY65243.1 - 0.031 14.0 2.1 0.046 13.4 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) ADIP PF11559.8 KIY65243.1 - 0.033 14.3 15.0 0.032 14.3 13.4 1.7 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding SlyX PF04102.12 KIY65243.1 - 0.046 14.3 12.3 1.7 9.3 2.3 2.7 1 1 1 2 2 2 0 SlyX DUF641 PF04859.12 KIY65243.1 - 0.047 14.0 9.8 0.075 13.4 9.8 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) DUF4407 PF14362.6 KIY65243.1 - 0.052 12.9 8.8 0.072 12.4 8.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PMC2NT PF08066.12 KIY65243.1 - 0.057 14.1 2.1 0.1 13.3 1.2 2.0 1 1 1 2 2 1 0 PMC2NT (NUC016) domain DivIC PF04977.15 KIY65243.1 - 0.063 13.1 20.3 0.5 10.2 6.7 3.2 1 1 2 3 3 3 0 Septum formation initiator Lebercilin PF15619.6 KIY65243.1 - 0.073 12.7 15.9 0.13 11.9 15.9 1.3 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease DUF4472 PF14739.6 KIY65243.1 - 0.076 13.8 11.8 0.14 12.9 11.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) ZapB PF06005.12 KIY65243.1 - 0.077 13.5 24.5 0.74 10.3 5.1 2.8 1 1 2 3 3 3 0 Cell division protein ZapB Phage_GPO PF05929.11 KIY65243.1 - 0.094 12.3 4.3 0.12 11.9 4.3 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase ERM PF00769.19 KIY65243.1 - 0.11 12.2 24.0 0.16 11.8 24.0 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family FAM76 PF16046.5 KIY65243.1 - 0.14 11.5 2.8 0.22 10.8 2.8 1.3 1 0 0 1 1 1 0 FAM76 protein Seryl_tRNA_N PF02403.22 KIY65243.1 - 0.15 12.3 11.1 0.26 11.6 11.1 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain TMF_TATA_bd PF12325.8 KIY65243.1 - 0.18 12.1 15.9 0.3 11.3 15.9 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding FlxA PF14282.6 KIY65243.1 - 0.18 11.8 7.1 0.34 10.9 7.1 1.5 1 0 0 1 1 1 0 FlxA-like protein Fib_alpha PF08702.10 KIY65243.1 - 0.22 11.7 6.8 0.45 10.7 5.5 1.8 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family FapA PF03961.13 KIY65243.1 - 0.3 9.6 8.6 0.4 9.2 8.6 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF4795 PF16043.5 KIY65243.1 - 0.46 10.1 8.7 0.28 10.8 6.2 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) Atg14 PF10186.9 KIY65243.1 - 0.47 9.5 11.2 0.71 8.9 11.2 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 KASH_CCD PF14662.6 KIY65243.1 - 0.55 10.0 18.4 15 5.3 18.2 2.1 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH TMPIT PF07851.13 KIY65243.1 - 0.59 9.3 7.7 0.81 8.9 7.7 1.1 1 0 0 1 1 1 0 TMPIT-like protein UPF0242 PF06785.11 KIY65243.1 - 0.62 10.1 14.8 1.1 9.3 14.8 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus NRBF2 PF08961.10 KIY65243.1 - 0.63 9.6 11.3 0.073 12.7 1.9 2.2 1 1 1 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator V_ATPase_I PF01496.19 KIY65243.1 - 0.65 7.8 8.6 0.87 7.4 8.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3450 PF11932.8 KIY65243.1 - 0.67 9.2 15.1 2.8 7.2 13.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) BLOC1_2 PF10046.9 KIY65243.1 - 0.67 10.3 7.3 8.8 6.7 3.4 2.2 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4337 PF14235.6 KIY65243.1 - 0.68 10.0 7.3 1 9.5 7.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) FmiP_Thoc5 PF09766.9 KIY65243.1 - 0.91 8.7 10.3 1.2 8.4 10.3 1.1 1 0 0 1 1 1 0 Fms-interacting protein/Thoc5 DUF1664 PF07889.12 KIY65243.1 - 0.94 9.5 5.3 1.9 8.5 3.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF724 PF05266.14 KIY65243.1 - 1.1 9.0 15.4 1.1 9.0 1.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) bZIP_1 PF00170.21 KIY65243.1 - 1.1 9.4 20.1 0.13 12.4 2.9 2.9 1 1 2 3 3 3 0 bZIP transcription factor Vac_Fusion PF02346.16 KIY65243.1 - 1.2 8.8 4.3 4.6 7.0 0.3 2.2 2 0 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 XRN_M PF17846.1 KIY65243.1 - 1.5 7.7 7.7 2.1 7.2 7.7 1.1 1 0 0 1 1 1 0 Xrn1 helical domain YabA PF06156.13 KIY65243.1 - 1.6 9.4 13.0 0.66 10.6 1.9 2.3 1 1 1 2 2 2 0 Initiation control protein YabA Exonuc_VII_L PF02601.15 KIY65243.1 - 2.3 7.7 7.5 3.1 7.3 7.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Prefoldin_2 PF01920.20 KIY65243.1 - 2.4 8.1 15.2 2.7 8.0 1.9 2.6 1 1 0 2 2 2 0 Prefoldin subunit FUSC PF04632.12 KIY65243.1 - 3.3 6.1 5.5 4.2 5.8 5.5 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family APG6_N PF17675.1 KIY65243.1 - 4.8 7.7 23.9 9.6 6.7 23.9 1.5 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF2681 PF10883.8 KIY65243.1 - 5 7.6 10.4 4.8 7.7 7.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2681) 5_nucleotid PF05761.14 KIY65243.1 - 5.4 5.8 8.2 7.3 5.4 8.2 1.1 1 0 0 1 1 1 0 5' nucleotidase family Seadorna_VP6 PF07407.11 KIY65243.1 - 6 5.7 7.8 2.1 7.2 0.2 2.0 1 1 1 2 2 2 0 Seadornavirus VP6 protein PRKG1_interact PF15898.5 KIY65243.1 - 6.1 7.8 18.1 12 6.8 17.8 1.6 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain Csm1_N PF18504.1 KIY65243.1 - 6.6 7.2 17.2 1.5 9.2 10.0 2.9 2 1 1 3 3 3 0 Csm1 N-terminal domain Vfa1 PF08432.10 KIY65243.1 - 7.6 6.8 12.4 3 8.2 0.3 2.2 1 1 1 2 2 2 0 AAA-ATPase Vps4-associated protein 1 TMF_DNA_bd PF12329.8 KIY65243.1 - 8.4 6.5 22.4 0.81 9.7 14.5 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF4375 PF14300.6 KIY65244.1 - 0.1 12.9 0.1 0.19 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4375) IPK PF03770.16 KIY65247.1 - 6e-47 160.1 0.0 8.2e-47 159.6 0.0 1.2 1 0 0 1 1 1 1 Inositol polyphosphate kinase Glyco_hydro_62 PF03664.13 KIY65249.1 - 0.012 14.9 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 62 PIG-S PF10510.9 KIY65250.1 - 0.18 10.6 1.3 0.22 10.3 1.3 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein BUD22 PF09073.10 KIY65250.1 - 0.28 10.5 10.3 0.33 10.3 10.3 1.0 1 0 0 1 1 1 0 BUD22 SCP1201-deam PF14428.6 KIY65250.1 - 0.41 10.5 2.2 2.5 8.0 1.6 2.0 1 1 1 2 2 2 0 SCP1.201-like deaminase Cauli_VI PF01693.16 KIY65251.1 - 5.2e-05 23.5 0.3 0.00016 21.9 0.3 1.9 1 0 0 1 1 1 1 Caulimovirus viroplasmin DUF4128 PF13554.6 KIY65253.1 - 0.0043 17.1 0.0 0.0076 16.3 0.0 1.3 1 0 0 1 1 1 1 Bacteriophage related domain of unknown function KDZ PF18758.1 KIY65255.1 - 3.6e-46 157.6 0.0 6.1e-46 156.8 0.0 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KIY65255.1 - 6.1e-29 100.3 0.0 1.4e-28 99.1 0.0 1.7 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KIY65255.1 - 0.0031 17.6 0.1 0.018 15.2 0.0 2.3 3 0 0 3 3 3 1 CxC1 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 KIY65255.1 - 0.088 12.7 0.0 0.088 12.7 0.0 2.8 3 0 0 3 3 3 0 CxC3 like cysteine cluster associated with KDZ transposases Herpes_ORF11 PF04797.13 KIY65256.1 - 0.11 11.3 0.1 0.15 10.8 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus dUTPase protein MpPF26 PF07666.11 KIY65256.1 - 2.4 8.3 17.4 0.12 12.4 2.7 3.0 2 1 1 3 3 3 0 M penetrans paralogue family 26 zinc_ribbon_15 PF17032.5 KIY65257.1 - 1.1e-05 26.1 0.1 1.7e-05 25.5 0.1 1.3 1 0 0 1 1 1 1 zinc-ribbon family Zn_Tnp_IS1595 PF12760.7 KIY65257.1 - 0.003 17.5 0.3 0.008 16.1 0.3 1.7 1 1 0 1 1 1 1 Transposase zinc-ribbon domain FYVE_2 PF02318.16 KIY65257.1 - 0.12 12.6 1.6 4.9 7.4 0.1 2.0 2 0 0 2 2 2 0 FYVE-type zinc finger RecR PF02132.15 KIY65257.1 - 0.2 11.2 1.6 4.4 7.0 0.2 2.2 2 0 0 2 2 2 0 RecR protein PWWP PF00855.17 KIY65258.1 - 0.054 13.9 0.1 0.11 12.9 0.0 1.6 2 0 0 2 2 2 0 PWWP domain ORC6 PF05460.13 KIY65258.1 - 0.24 10.7 2.0 0.27 10.5 2.0 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) GATA PF00320.27 KIY65259.1 - 5.8e-26 89.8 20.1 1.6e-13 50.0 6.8 2.5 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 KIY65259.1 - 1.3e-06 27.8 2.5 0.001 18.6 0.1 2.5 2 0 0 2 2 2 2 TFIIB zinc-binding DZR PF12773.7 KIY65259.1 - 0.019 15.0 8.7 0.48 10.5 0.7 3.0 1 1 2 3 3 3 0 Double zinc ribbon Cytochrom_c3_2 PF14537.6 KIY65259.1 - 0.81 10.2 7.1 3 8.4 7.4 1.9 1 1 1 2 2 2 0 Cytochrome c3 Zn-ribbon_8 PF09723.10 KIY65259.1 - 1 9.6 6.4 15 5.8 0.9 2.8 2 1 1 3 3 3 0 Zinc ribbon domain NMD3 PF04981.13 KIY65259.1 - 1.6 8.1 5.4 1.6 8.1 0.3 2.1 1 1 1 2 2 2 0 NMD3 family eIF-5_eIF-2B PF01873.17 KIY65259.1 - 2 8.3 8.0 5.2 7.0 1.3 2.2 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Auto_anti-p27 PF06677.12 KIY65259.1 - 4 7.7 7.2 2.6 8.3 0.9 2.5 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Cytochrome_C7 PF14522.6 KIY65259.1 - 4.5 7.3 9.7 33 4.6 9.7 2.2 1 1 0 1 1 1 0 Cytochrome c7 and related cytochrome c Plavaka PF18759.1 KIY65261.1 - 4.7e-117 390.8 0.0 6.5e-117 390.4 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase zf-met PF12874.7 KIY65261.1 - 0.0041 17.5 0.3 0.013 15.8 0.3 1.9 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KIY65261.1 - 0.0042 17.8 2.6 0.01 16.6 0.8 2.7 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2 PF00096.26 KIY65261.1 - 0.019 15.4 0.9 0.019 15.4 0.9 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KIY65261.1 - 0.15 12.4 1.2 0.23 11.8 0.1 1.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Ribosomal_S5_C PF03719.15 KIY65265.1 - 0.25 10.8 0.9 1.6 8.3 0.0 2.7 4 0 0 4 4 4 0 Ribosomal protein S5, C-terminal domain Ubiquitin_2 PF14560.6 KIY65269.1 - 0.15 12.5 0.0 0.28 11.7 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain FSH1 PF03959.13 KIY65270.1 - 6.9e-33 114.1 0.0 1.2e-32 113.3 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Pox_Ag35 PF03286.14 KIY65270.1 - 0.9 9.3 3.1 1.8 8.3 3.1 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Nup35_RRM PF05172.13 KIY65271.1 - 6.2e-06 26.1 0.0 2.4e-05 24.2 0.0 1.8 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Glyco_hydro_31 PF01055.26 KIY65272.1 - 2.2e-145 485.2 6.2 3e-145 484.8 6.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KIY65272.1 - 7.2e-14 51.9 0.0 2.2e-13 50.3 0.0 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like DUF5110 PF17137.4 KIY65272.1 - 1.3e-06 28.5 0.1 3.3e-06 27.3 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) Gb3_synth PF04572.12 KIY65272.1 - 0.097 12.8 0.1 0.21 11.8 0.1 1.4 1 0 0 1 1 1 0 Alpha 1,4-glycosyltransferase conserved region DUF4968 PF16338.5 KIY65272.1 - 0.19 12.1 0.0 0.41 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4968) IBN_N PF03810.19 KIY65274.1 - 2e-07 30.8 0.0 3.5e-05 23.6 0.0 3.2 3 0 0 3 3 3 1 Importin-beta N-terminal domain RTP1_C1 PF10363.9 KIY65274.1 - 8.9e-05 22.6 0.3 0.0039 17.4 0.1 3.2 1 1 1 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 Cnd1 PF12717.7 KIY65274.1 - 0.0001 22.4 1.0 0.0051 16.9 0.2 3.0 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 KIY65274.1 - 0.0025 16.5 1.9 0.0025 16.5 1.9 3.1 4 0 0 4 4 4 1 Adaptin N terminal region Thiamine_BP PF01910.17 KIY65274.1 - 0.0026 17.6 0.2 1.8 8.6 0.1 2.8 2 0 0 2 2 2 2 Thiamine-binding protein HEAT PF02985.22 KIY65274.1 - 0.012 15.8 0.2 19 5.9 0.0 4.0 3 0 0 3 3 2 0 HEAT repeat HEAT_2 PF13646.6 KIY65274.1 - 0.019 15.3 7.7 0.069 13.5 0.0 4.7 5 0 0 5 5 4 0 HEAT repeats V-ATPase_H_C PF11698.8 KIY65274.1 - 0.13 12.4 0.0 0.45 10.6 0.0 2.0 1 0 0 1 1 1 0 V-ATPase subunit H Tti2 PF10521.9 KIY65274.1 - 0.19 11.3 2.2 0.41 10.1 0.2 2.7 3 1 0 3 3 3 0 Tti2 family GP17 PF17420.2 KIY65274.1 - 1.2 9.3 5.0 10 6.3 5.5 2.2 2 0 0 2 2 2 0 Superinfection exclusion gene product 17 DUF2457 PF10446.9 KIY65274.1 - 9 5.3 12.6 13 4.8 12.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Arrestin_C PF02752.22 KIY65276.1 - 0.018 15.5 0.0 2.6 8.5 0.0 2.3 2 0 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain Bac_rhamnosid PF05592.11 KIY65276.1 - 0.2 11.7 0.0 0.36 10.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase concanavalin-like domain Brix PF04427.18 KIY65277.1 - 2e-36 125.9 0.1 2.9e-36 125.4 0.1 1.2 1 0 0 1 1 1 1 Brix domain TRAM_LAG1_CLN8 PF03798.16 KIY65278.1 - 7.8e-28 97.6 10.9 9.8e-28 97.2 10.9 1.1 1 0 0 1 1 1 1 TLC domain Per1 PF04080.13 KIY65278.1 - 0.11 12.3 2.7 0.16 11.7 2.7 1.3 1 0 0 1 1 1 0 Per1-like family Vps54 PF07928.12 KIY65279.1 - 6.6e-51 172.3 2.2 2.2e-50 170.6 2.2 2.0 1 0 0 1 1 1 1 Vps54-like protein Vps54_N PF10475.9 KIY65279.1 - 0.00023 20.5 0.1 0.00045 19.6 0.1 1.5 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex COG5 PF10392.9 KIY65279.1 - 0.005 17.0 2.8 0.005 17.0 2.8 2.6 3 0 0 3 3 3 1 Golgi transport complex subunit 5 DUF2889 PF11136.8 KIY65279.1 - 0.012 15.9 0.3 0.029 14.7 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2889) DUF2451 PF10474.9 KIY65279.1 - 0.02 14.7 0.4 0.062 13.1 0.4 1.8 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2451) Sec8_exocyst PF04048.14 KIY65279.1 - 0.076 12.9 1.2 0.25 11.2 0.9 2.1 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain Phycobilisome PF00502.19 KIY65279.1 - 0.099 12.6 0.1 0.22 11.5 0.1 1.6 1 0 0 1 1 1 0 Phycobilisome protein UTP25 PF06862.12 KIY65279.1 - 0.12 11.1 0.5 0.21 10.3 0.5 1.3 1 0 0 1 1 1 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 L51_S25_CI-B8 PF05047.16 KIY65280.1 - 1.4e-08 34.5 0.1 3e-08 33.4 0.1 1.6 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain FYVE PF01363.21 KIY65281.1 - 0.032 14.3 17.2 0.075 13.2 3.5 2.6 2 1 0 2 2 2 0 FYVE zinc finger Siva PF05458.12 KIY65281.1 - 0.055 13.2 20.9 0.027 14.2 12.6 2.2 2 0 0 2 2 2 0 Cd27 binding protein (Siva) FYVE_2 PF02318.16 KIY65281.1 - 7.1 6.9 16.6 2.5 8.3 5.5 2.3 2 0 0 2 2 2 0 FYVE-type zinc finger E1-E2_ATPase PF00122.20 KIY65282.1 - 0.055 13.0 0.3 0.086 12.4 0.3 1.2 1 0 0 1 1 1 0 E1-E2 ATPase DUF1713 PF08213.11 KIY65283.1 - 2.8e-07 30.3 19.3 4.5e-07 29.7 19.3 1.3 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) DUF5541 PF17695.1 KIY65283.1 - 0.054 13.9 0.2 0.12 12.9 0.0 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5541) Dynamin_M PF01031.20 KIY65284.1 - 3.4e-29 102.0 0.0 7.5e-28 97.6 0.0 2.4 1 1 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 KIY65284.1 - 7.4e-29 101.0 0.0 2.1e-28 99.5 0.0 1.8 2 0 0 2 2 2 1 Dynamin family GED PF02212.18 KIY65284.1 - 7.2e-08 32.5 0.6 2.2e-07 30.9 0.2 2.1 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KIY65284.1 - 0.00041 20.4 0.4 0.005 16.9 0.4 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP-bdg_N PF13167.6 KIY65284.1 - 0.014 16.1 0.0 0.044 14.4 0.0 1.8 1 0 0 1 1 1 0 GTP-binding GTPase N-terminal AAA_16 PF13191.6 KIY65284.1 - 0.059 13.7 0.1 0.33 11.3 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.27 KIY65284.1 - 0.077 13.5 0.0 0.21 12.1 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Syja_N PF02383.18 KIY65285.1 - 1.5e-93 313.7 0.0 1.9e-93 313.3 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.8 KIY65285.1 - 1.8e-30 105.0 0.0 3.7e-30 104.0 0.0 1.5 1 0 0 1 1 1 1 Inositol phosphatase AAA_21 PF13304.6 KIY65285.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF1131 PF06572.12 KIY65287.1 - 0.03 14.0 0.1 0.043 13.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1131) F-box-like PF12937.7 KIY65288.1 - 1.6e-07 31.1 0.1 4.1e-07 29.8 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KIY65289.1 - 6.2e-09 35.6 0.3 1.4e-08 34.5 0.3 1.6 1 0 0 1 1 1 1 F-box-like SID-1_RNA_chan PF13965.6 KIY65290.1 - 0.038 12.4 2.5 0.045 12.2 2.5 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Tetraspanin PF00335.20 KIY65290.1 - 0.87 9.3 5.0 1.1 8.9 5.0 1.3 1 0 0 1 1 1 0 Tetraspanin family Proteasome PF00227.26 KIY65291.1 - 2.2e-49 167.5 0.1 2.7e-49 167.3 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit AA_permease PF00324.21 KIY65292.1 - 1.5e-116 389.9 31.0 1.7e-116 389.7 31.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KIY65292.1 - 1.5e-23 83.3 37.1 2.1e-23 82.9 37.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KIY65293.1 - 8e-112 374.3 37.3 9.1e-112 374.1 37.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KIY65293.1 - 4.1e-20 72.0 42.3 5.7e-20 71.5 42.3 1.1 1 0 0 1 1 1 1 Amino acid permease LIM PF00412.22 KIY65294.1 - 2.4e-14 53.3 22.6 8.9e-10 38.7 5.3 3.8 4 0 0 4 4 4 3 LIM domain zf_UBZ PF18439.1 KIY65294.1 - 0.083 12.5 0.0 0.083 12.5 0.0 4.7 5 1 1 6 6 6 0 Ubiquitin-Binding Zinc Finger DHHC PF01529.20 KIY65295.1 - 1.6e-30 105.9 7.8 1.6e-30 105.9 7.8 1.8 2 0 0 2 2 2 1 DHHC palmitoyltransferase ABC_export PF16962.5 KIY65296.1 - 0.37 9.2 1.5 0.27 9.7 0.2 1.4 2 0 0 2 2 2 0 Putative ABC exporter IF4E PF01652.18 KIY65297.1 - 1.6e-52 177.5 0.0 2.3e-52 177.0 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DUF1102 PF06510.11 KIY65297.1 - 0.1 12.8 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1102) Ribosomal_L7Ae PF01248.26 KIY65298.1 - 9.7e-25 86.1 0.1 1.2e-24 85.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 KIY65298.1 - 0.00051 20.1 0.0 0.00058 20.0 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.6 KIY65298.1 - 0.00098 19.0 0.0 0.0015 18.4 0.0 1.3 1 0 0 1 1 1 1 PELOTA RNA binding domain UQ_con PF00179.26 KIY65299.1 - 1.7e-47 160.6 0.0 1.9e-47 160.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KIY65299.1 - 0.00022 20.9 0.0 0.00026 20.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KIY65299.1 - 0.04 14.2 1.4 0.12 12.7 1.4 1.7 1 1 0 1 1 1 0 RWD domain DDE_1 PF03184.19 KIY65300.1 - 1e-07 31.8 0.0 1.1e-06 28.5 0.0 2.3 2 0 0 2 2 2 1 DDE superfamily endonuclease Borrelia_P83 PF05262.11 KIY65300.1 - 0.0039 15.8 0.6 0.0055 15.3 0.6 1.2 1 0 0 1 1 1 1 Borrelia P83/100 protein RNA_polI_A34 PF08208.11 KIY65300.1 - 0.015 15.4 1.6 0.028 14.5 1.6 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 UIM PF02809.20 KIY65303.1 - 0.0014 18.4 12.0 0.27 11.3 0.5 2.9 2 0 0 2 2 2 2 Ubiquitin interaction motif CLZ PF16526.5 KIY65303.1 - 0.14 12.5 1.3 0.27 11.6 0.0 2.2 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels PspA_IM30 PF04012.12 KIY65303.1 - 0.42 10.2 5.8 0.076 12.6 0.6 2.0 2 0 0 2 2 2 0 PspA/IM30 family TMF_TATA_bd PF12325.8 KIY65303.1 - 1.1 9.5 0.0 1.1 9.5 0.0 2.9 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding Pkinase PF00069.25 KIY65304.1 - 6.3e-67 225.7 0.0 7.7e-67 225.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY65304.1 - 5.9e-29 101.1 0.0 7.8e-29 100.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KIY65304.1 - 0.028 13.4 0.0 0.039 12.9 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain WD40 PF00400.32 KIY65304.1 - 0.043 14.7 0.0 0.12 13.3 0.0 1.8 1 0 0 1 1 1 0 WD domain, G-beta repeat APH PF01636.23 KIY65304.1 - 0.059 13.3 0.0 0.14 12.0 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 KIY65304.1 - 0.13 11.6 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LRR_4 PF12799.7 KIY65305.1 - 0.0012 19.2 0.1 0.13 12.8 0.0 3.4 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) Clathrin_lg_ch PF01086.17 KIY65306.1 - 1.7e-43 149.3 1.4 2e-43 149.1 1.4 1.2 1 0 0 1 1 1 1 Clathrin light chain HSP70 PF00012.20 KIY65306.1 - 0.11 10.6 1.9 0.12 10.5 1.9 1.1 1 0 0 1 1 1 0 Hsp70 protein RsbRD_N PF14361.6 KIY65306.1 - 0.16 12.6 2.8 0.26 12.0 2.8 1.3 1 0 0 1 1 1 0 RsbT co-antagonist protein rsbRD N-terminal domain PGP_phosphatase PF09419.10 KIY65307.1 - 4.1e-42 143.7 0.0 5.7e-42 143.2 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 KIY65307.1 - 0.021 14.9 0.0 0.037 14.1 0.0 1.3 1 0 0 1 1 1 0 HAD-hyrolase-like IGPS PF00218.21 KIY65308.1 - 9e-85 283.9 0.0 1.5e-84 283.2 0.0 1.3 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase GATase PF00117.28 KIY65308.1 - 5.6e-44 150.2 0.0 9.7e-44 149.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I PRAI PF00697.22 KIY65308.1 - 1.7e-39 135.6 0.1 9.2e-19 68.0 0.0 3.3 2 1 1 3 3 3 3 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Peptidase_C26 PF07722.13 KIY65308.1 - 1.5e-07 31.4 0.1 5.4e-07 29.6 0.1 1.9 1 1 0 1 1 1 1 Peptidase C26 QRPTase_C PF01729.19 KIY65308.1 - 0.0014 18.4 0.1 0.054 13.3 0.1 2.8 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain Pex24p PF06398.11 KIY65309.1 - 1.1e-33 116.7 0.0 1.4e-33 116.4 0.0 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin VirB8 PF04335.13 KIY65309.1 - 0.044 13.6 0.0 0.074 12.9 0.0 1.3 1 0 0 1 1 1 0 VirB8 protein SIR2 PF02146.17 KIY65310.1 - 1.1e-25 90.6 0.0 1.3e-22 80.6 0.0 3.0 1 1 0 1 1 1 1 Sir2 family API5 PF05918.11 KIY65311.1 - 5.2 5.8 13.5 0.089 11.6 3.7 2.1 2 0 0 2 2 2 0 Apoptosis inhibitory protein 5 (API5) Glyco_hydro_88 PF07470.13 KIY65312.1 - 3.3e-09 36.3 1.0 4.2e-09 36.0 0.4 1.4 2 0 0 2 2 2 1 Glycosyl Hydrolase Family 88 Hydrolase_4 PF12146.8 KIY65313.1 - 1.2e-49 168.8 0.0 1.4e-49 168.5 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KIY65313.1 - 2.5e-12 47.9 0.4 3.2e-12 47.5 0.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KIY65313.1 - 2.2e-09 37.4 0.3 9.5e-08 32.0 0.3 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold AXE1 PF05448.12 KIY65313.1 - 0.16 10.6 0.5 0.33 9.6 0.0 1.7 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.21 KIY65313.1 - 0.22 11.0 1.2 2.7 7.4 0.0 2.4 2 1 0 2 2 2 0 Prolyl oligopeptidase family Ntox24 PF15529.6 KIY65314.1 - 0.11 12.8 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial toxin 24 PB1 PF00564.24 KIY65315.1 - 2.7e-12 46.5 0.0 4.6e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 PB1 domain TPR_2 PF07719.17 KIY65315.1 - 4.3e-09 35.8 1.9 0.19 11.9 0.2 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 KIY65315.1 - 3.4e-08 33.0 1.2 0.68 9.9 0.0 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 KIY65315.1 - 1.8e-06 27.7 1.0 1.1 9.6 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KIY65315.1 - 5.4e-05 23.4 0.8 0.024 14.9 0.0 3.3 2 1 2 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 KIY65315.1 - 0.013 15.2 0.2 0.054 13.2 0.0 2.3 2 0 0 2 2 2 0 TPR repeat TPR_7 PF13176.6 KIY65315.1 - 0.092 12.8 0.5 20 5.5 0.1 3.9 3 1 0 3 3 3 0 Tetratricopeptide repeat Zn_clus PF00172.18 KIY65316.1 - 1.3e-07 31.6 10.8 4.1e-07 30.0 10.8 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KIY65316.1 - 3.6e-06 26.2 0.0 6e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain MGTL PF17059.5 KIY65316.1 - 0.17 11.7 1.1 0.59 10.0 1.1 1.8 1 0 0 1 1 1 0 MgtA leader peptide Ndc1_Nup PF09531.10 KIY65317.1 - 3.5e-63 214.3 22.7 2e-62 211.8 22.7 1.8 1 1 0 1 1 1 1 Nucleoporin protein Ndc1-Nup ABC_membrane PF00664.23 KIY65318.1 - 2.1e-52 178.5 5.0 2.9e-52 178.0 5.0 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KIY65318.1 - 1.3e-30 106.7 0.0 3.8e-30 105.2 0.0 1.8 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KIY65318.1 - 1.5e-05 24.5 0.1 0.0058 16.1 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KIY65318.1 - 6.3e-05 23.4 2.7 8.2e-05 23.0 0.1 2.6 3 1 1 4 4 4 1 AAA ATPase domain DUF87 PF01935.17 KIY65318.1 - 0.031 14.4 0.1 0.061 13.4 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 KIY65318.1 - 0.082 12.7 0.2 0.24 11.2 0.2 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain NUDIX PF00293.28 KIY65319.1 - 1.7e-15 57.2 0.0 3.3e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.11 KIY65319.1 - 5.7e-09 36.6 0.0 1.1e-08 35.6 0.0 1.5 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.11 KIY65319.1 - 0.0037 16.9 0.7 0.0069 16.0 0.7 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain HrpB2 PF09487.10 KIY65320.1 - 0.06 13.8 0.5 0.099 13.1 0.5 1.4 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB2) Band_7 PF01145.25 KIY65320.1 - 0.27 11.2 2.5 0.39 10.7 2.5 1.4 1 0 0 1 1 1 0 SPFH domain / Band 7 family RHH_6 PF16762.5 KIY65320.1 - 0.41 11.3 2.8 2.1 9.1 0.1 2.4 1 1 2 3 3 3 0 Ribbon-helix-helix domain DUF4770 PF15994.5 KIY65321.1 - 1.8 8.7 15.9 3.3 7.9 10.5 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) eIF-3_zeta PF05091.12 KIY65321.1 - 3.7 6.4 20.6 0.18 10.8 12.8 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF2149 PF09919.9 KIY65321.1 - 4.5 7.6 5.2 8.8 6.7 5.2 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2149) DUF1764 PF08576.10 KIY65321.1 - 6 7.8 17.3 0.15 12.9 7.0 3.1 4 0 0 4 4 4 0 Eukaryotic protein of unknown function (DUF1764) SpoIIP PF07454.11 KIY65321.1 - 6.8 6.1 14.0 1 8.8 8.3 2.2 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Folate_carrier PF01770.18 KIY65321.1 - 9.1 4.9 7.1 16 4.1 7.1 1.3 1 0 0 1 1 1 0 Reduced folate carrier Gemini_mov PF01708.16 KIY65322.1 - 0.13 12.1 0.7 0.37 10.6 0.2 2.1 2 0 0 2 2 2 0 Geminivirus putative movement protein DUF3112 PF11309.8 KIY65322.1 - 0.32 10.4 5.0 0.71 9.3 5.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3112) Pox_A14 PF05767.12 KIY65322.1 - 3.6 7.8 7.3 0.93 9.7 2.0 2.2 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 Glyco_hydro_12 PF01670.16 KIY65324.1 - 2.2e-43 148.8 9.8 2.5e-43 148.6 9.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 Multi_Drug_Res PF00893.19 KIY65324.1 - 0.061 14.0 0.1 0.13 13.0 0.1 1.5 1 0 0 1 1 1 0 Small Multidrug Resistance protein G-alpha PF00503.20 KIY65328.1 - 5.2e-114 381.1 0.6 6.1e-114 380.9 0.6 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KIY65328.1 - 3.8e-16 59.0 2.3 1.1e-11 44.5 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KIY65328.1 - 9.2e-05 21.9 1.1 0.0049 16.2 0.0 2.4 2 1 0 2 2 2 1 Gtr1/RagA G protein conserved region Roc PF08477.13 KIY65328.1 - 0.0036 17.5 0.2 2.7 8.2 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KIY65328.1 - 0.041 14.0 0.1 1.7 8.7 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_29 PF13555.6 KIY65328.1 - 0.06 13.1 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain zf-CHC2 PF01807.20 KIY65328.1 - 0.079 12.8 0.0 0.28 11.0 0.0 1.8 2 0 0 2 2 2 0 CHC2 zinc finger FtsK_SpoIIIE PF01580.18 KIY65328.1 - 0.1 11.9 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Arylesterase PF01731.20 KIY65329.1 - 9.9e-06 25.7 0.0 0.0017 18.5 0.0 2.3 2 0 0 2 2 2 2 Arylesterase Str_synth PF03088.16 KIY65329.1 - 5.4e-05 23.2 0.0 0.0012 18.9 0.0 2.6 3 0 0 3 3 3 1 Strictosidine synthase SGL PF08450.12 KIY65329.1 - 0.00032 20.4 0.0 0.041 13.5 0.0 2.4 1 1 0 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 KIY65329.1 - 0.0035 17.3 1.1 0.24 11.5 0.0 3.7 4 0 0 4 4 4 1 NHL repeat Lactonase PF10282.9 KIY65329.1 - 0.02 14.1 0.0 0.097 11.9 0.0 1.8 1 1 0 1 1 1 0 Lactonase, 7-bladed beta-propeller HNH_2 PF13391.6 KIY65330.1 - 0.00011 22.3 0.0 0.00035 20.6 0.0 1.9 2 0 0 2 2 2 1 HNH endonuclease Peptidase_M28 PF04389.17 KIY65331.1 - 4.1e-26 91.9 0.0 6.6e-26 91.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KIY65331.1 - 3.2e-07 30.2 0.0 5.3e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Sigma70_ner PF04546.13 KIY65332.1 - 0.18 11.7 8.7 0.32 10.9 8.7 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region zf-H2C2_5 PF13909.6 KIY65333.1 - 9e-05 22.1 15.2 0.0072 16.1 5.0 3.0 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 KIY65333.1 - 0.063 13.7 8.2 1.1 9.8 0.3 3.6 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2 PF00096.26 KIY65333.1 - 0.12 12.8 10.8 0.3 11.6 0.3 3.6 3 0 0 3 3 3 0 Zinc finger, C2H2 type DUF4551 PF15087.6 KIY65333.1 - 3.2 6.5 8.9 4.6 5.9 8.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Glyco_hydro_62 PF03664.13 KIY65334.1 - 6.9e-129 429.0 11.3 7.9e-129 428.8 11.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 RRM_1 PF00076.22 KIY65336.1 - 2.3e-28 97.8 0.0 1.4e-13 50.4 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KIY65336.1 - 5.5e-10 39.2 0.1 0.00015 21.8 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif Pkinase PF00069.25 KIY65339.1 - 6.2e-67 225.7 0.0 7.2e-67 225.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY65339.1 - 3e-33 115.2 0.0 3.8e-33 114.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY65339.1 - 0.00057 19.3 0.0 0.0009 18.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like zf-H2C2_5 PF13909.6 KIY65341.1 - 9.3e-09 34.9 5.3 0.00032 20.4 0.2 2.7 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 KIY65341.1 - 8.7e-05 22.8 11.3 0.11 12.9 0.1 4.3 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KIY65341.1 - 0.0001 22.6 3.0 0.026 15.0 0.2 2.8 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KIY65341.1 - 0.12 13.3 15.5 0.3 12.0 1.0 4.1 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KIY65341.1 - 0.41 10.7 4.7 11 6.1 0.1 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-UBP PF02148.19 KIY65341.1 - 6.6 7.1 10.8 30 5.1 10.4 2.4 1 1 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein ARTD15_N PF18084.1 KIY65343.1 - 0.049 13.9 0.0 0.082 13.2 0.0 1.5 1 1 0 1 1 1 0 ARTD15 N-terminal domain Sec39 PF08314.11 KIY65344.1 - 4.9e-12 45.2 0.0 3.7e-10 39.0 0.0 2.2 1 1 0 1 1 1 1 Secretory pathway protein Sec39 BLOC1_2 PF10046.9 KIY65345.1 - 0.0086 16.4 4.6 1.3 9.4 0.4 2.3 2 0 0 2 2 2 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 TMF_DNA_bd PF12329.8 KIY65345.1 - 0.021 14.8 3.6 0.021 14.8 3.6 2.5 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding KLRAQ PF10205.9 KIY65345.1 - 0.45 10.8 6.2 1.3 9.3 3.7 2.2 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein Spc7 PF08317.11 KIY65345.1 - 2.1 7.2 12.6 2.3 7.1 9.6 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein ANAPC4_WD40 PF12894.7 KIY65346.1 - 1e-08 35.4 0.0 0.00018 21.7 0.0 3.3 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KIY65346.1 - 2.7e-06 28.0 0.3 0.0013 19.5 0.0 4.3 4 0 0 4 4 4 1 WD domain, G-beta repeat CzcE PF16986.5 KIY65346.1 - 0.14 12.5 0.5 15 6.0 0.1 3.1 3 0 0 3 3 3 0 Heavy-metal resistance protein CzcE Na_H_Exchanger PF00999.21 KIY65349.1 - 6.3e-57 193.1 23.7 7.3e-57 192.9 23.7 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Kinocilin PF15033.6 KIY65350.1 - 0.13 11.9 0.4 0.38 10.4 0.4 1.9 1 0 0 1 1 1 0 Kinocilin protein ABC1 PF03109.16 KIY65351.1 - 4.6e-29 101.0 0.0 1e-28 99.9 0.0 1.6 2 0 0 2 2 2 1 ABC1 family Herpes_LMP1 PF05297.11 KIY65352.1 - 1.6 7.8 3.3 92 2.1 0.0 2.1 2 0 0 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) DUF2427 PF10348.9 KIY65352.1 - 6.4 6.6 9.3 0.24 11.2 0.5 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF2427) MscL PF01741.18 KIY65353.1 - 0.034 14.4 0.6 0.65 10.3 0.2 2.4 2 0 0 2 2 2 0 Large-conductance mechanosensitive channel, MscL PIG-P PF08510.12 KIY65353.1 - 0.42 10.5 5.0 3.9 7.4 2.7 2.9 3 0 0 3 3 3 0 PIG-P Methyltransf_25 PF13649.6 KIY65354.1 - 6.1e-18 65.3 0.0 1e-17 64.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIY65354.1 - 1.1e-14 54.8 0.0 1.6e-14 54.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIY65354.1 - 1.2e-12 48.0 0.0 1.5e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIY65354.1 - 2.3e-11 43.7 0.0 2.8e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIY65354.1 - 1.3e-07 32.3 0.0 3.6e-07 30.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIY65354.1 - 7.4e-07 28.7 0.0 1e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 KIY65354.1 - 3.7e-06 26.4 0.0 4.3e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase TPMT PF05724.11 KIY65354.1 - 0.00021 21.0 0.0 0.00033 20.4 0.0 1.2 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) TehB PF03848.14 KIY65354.1 - 0.00065 19.2 0.0 0.00095 18.6 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB PCMT PF01135.19 KIY65354.1 - 0.0053 16.5 0.0 0.007 16.1 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 KIY65354.1 - 0.0091 15.6 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain NodS PF05401.11 KIY65354.1 - 0.034 13.7 0.0 0.047 13.3 0.0 1.1 1 0 0 1 1 1 0 Nodulation protein S (NodS) PrmA PF06325.13 KIY65354.1 - 0.045 13.1 0.0 0.058 12.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) UPF0146 PF03686.13 KIY65354.1 - 0.059 13.2 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) UDPG_MGDP_dh_N PF03721.14 KIY65354.1 - 0.15 11.6 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Uso1_p115_C PF04871.13 KIY65355.1 - 4.2 7.8 5.0 0.8 10.1 0.6 1.8 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Ribosomal_L31e PF01198.19 KIY65356.1 - 1.4e-38 131.0 0.8 1.7e-38 130.7 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e AAA_10 PF12846.7 KIY65356.1 - 0.045 12.7 0.0 0.055 12.4 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain CFEM PF05730.11 KIY65357.1 - 1.2e-11 44.5 10.1 1.5e-11 44.2 10.1 1.1 1 0 0 1 1 1 1 CFEM domain PHD PF00628.29 KIY65358.1 - 5.5e-07 29.4 4.2 5.5e-07 29.4 4.2 4.0 4 1 1 5 5 5 1 PHD-finger Cutinase PF01083.22 KIY65359.1 - 2.9e-25 89.2 0.0 1.7e-24 86.7 0.0 1.9 2 0 0 2 2 2 1 Cutinase Abhydrolase_6 PF12697.7 KIY65359.1 - 0.00027 21.6 0.6 0.00037 21.2 0.6 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PE-PPE PF08237.11 KIY65359.1 - 0.027 14.0 0.0 0.039 13.5 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain VirJ PF06057.11 KIY65359.1 - 0.033 14.1 0.0 0.054 13.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Lipase_3 PF01764.25 KIY65359.1 - 0.13 12.1 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Cutinase PF01083.22 KIY65360.1 - 6e-23 81.7 0.0 2e-22 80.0 0.0 1.8 1 1 0 1 1 1 1 Cutinase Abhydrolase_6 PF12697.7 KIY65360.1 - 3.8e-05 24.4 1.3 5e-05 24.0 1.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PE-PPE PF08237.11 KIY65360.1 - 0.015 14.9 0.0 0.023 14.3 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain DUF3089 PF11288.8 KIY65360.1 - 0.049 13.2 0.0 0.095 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Abhydrolase_2 PF02230.16 KIY65360.1 - 0.17 11.6 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase EF-hand_1 PF00036.32 KIY65362.1 - 1.4e-38 127.5 12.3 4.4e-10 38.4 0.0 4.8 4 1 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KIY65362.1 - 1.3e-33 115.2 2.2 1.1e-15 57.8 0.6 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KIY65362.1 - 4.9e-31 104.0 5.2 1.3e-09 37.2 0.1 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 KIY65362.1 - 1.1e-29 102.0 10.8 2.7e-13 49.5 0.1 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 KIY65362.1 - 3.4e-26 89.5 6.2 1.6e-06 27.3 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 KIY65362.1 - 3.2e-16 59.4 0.2 2.3e-09 37.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 KIY65362.1 - 7.1e-09 35.6 0.6 0.0018 18.2 0.1 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KIY65362.1 - 3.2e-07 30.6 0.0 0.033 14.5 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 KIY65362.1 - 1.2e-06 28.4 0.2 0.043 13.8 0.0 3.3 3 1 1 4 4 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 KIY65362.1 - 4.5e-06 26.7 1.1 2.2e-05 24.4 0.1 2.3 2 2 0 2 2 2 1 Ca2+ insensitive EF hand TerB PF05099.13 KIY65362.1 - 0.00048 20.1 0.3 0.47 10.4 0.0 2.3 1 1 1 2 2 2 2 Tellurite resistance protein TerB Caleosin PF05042.13 KIY65362.1 - 0.00057 19.9 0.3 0.43 10.5 0.0 3.0 1 1 2 3 3 3 1 Caleosin related protein EF-hand_11 PF08976.11 KIY65362.1 - 0.0013 19.5 0.0 1 10.2 0.0 2.1 1 1 1 2 2 2 2 EF-hand domain DUF3349 PF11829.8 KIY65362.1 - 0.0018 19.0 0.2 1.5 9.6 0.0 2.8 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) DUF4497 PF14924.6 KIY65362.1 - 0.003 18.0 0.0 1.1 9.8 0.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF4497) DUF1103 PF06513.11 KIY65362.1 - 0.0031 17.2 0.8 0.0034 17.0 0.8 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) MotA_activ PF09114.10 KIY65362.1 - 0.0048 17.0 0.3 0.079 13.1 0.0 2.3 1 1 0 2 2 2 1 Transcription factor MotA, activation domain RNA_pol_Rpb4 PF03874.16 KIY65362.1 - 0.0049 17.2 0.4 3 8.2 0.1 2.6 3 0 0 3 3 3 1 RNA polymerase Rpb4 SurA_N_2 PF13623.6 KIY65362.1 - 0.0063 16.4 0.4 0.41 10.5 0.1 2.2 1 1 1 2 2 2 1 SurA N-terminal domain EF-hand_14 PF17959.1 KIY65362.1 - 0.011 16.0 0.1 5.8 7.3 0.0 2.4 1 1 1 2 2 2 0 EF-hand domain DUF1811 PF08838.10 KIY65362.1 - 0.03 14.5 0.0 7.5 6.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1811) Poly_export PF02563.16 KIY65362.1 - 0.032 14.5 0.1 0.77 10.0 0.0 2.6 2 2 1 3 3 3 0 Polysaccharide biosynthesis/export protein Spore_III_AB PF09548.10 KIY65362.1 - 0.036 14.2 0.3 0.078 13.1 0.2 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) SurA_N_3 PF13624.6 KIY65362.1 - 0.058 13.2 0.3 0.31 10.8 0.1 1.9 1 1 1 2 2 2 0 SurA N-terminal domain Fe_hyd_lg_C PF02906.14 KIY65362.1 - 0.08 12.6 0.4 0.14 11.8 0.4 1.5 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain Dockerin_1 PF00404.18 KIY65362.1 - 0.13 12.4 5.6 5.1 7.4 0.4 3.0 1 1 2 3 3 3 0 Dockerin type I domain Glyco_hydro_12 PF01670.16 KIY65363.1 - 3.5e-35 121.9 12.4 4.1e-35 121.7 12.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 EF-hand_1 PF00036.32 KIY65364.1 - 6.5e-30 100.4 6.8 9.5e-10 37.3 0.4 3.1 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 KIY65364.1 - 2.6e-23 82.2 1.0 3.3e-15 56.3 0.1 2.0 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KIY65364.1 - 7e-23 80.2 5.5 1.5e-09 37.5 0.3 3.0 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 KIY65364.1 - 5e-22 75.9 3.1 2.2e-08 33.3 0.0 3.2 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.6 KIY65364.1 - 1.1e-17 62.7 4.2 4.1e-06 26.0 0.0 3.2 3 0 0 3 3 3 3 EF hand EF-hand_9 PF14658.6 KIY65364.1 - 5.5e-10 39.4 0.1 0.0002 21.6 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 KIY65364.1 - 1.3e-05 25.1 1.3 0.0058 16.6 0.1 2.1 1 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KIY65364.1 - 0.00022 21.5 0.0 0.0097 16.2 0.0 2.0 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region DUF5580 PF17743.1 KIY65364.1 - 0.00029 19.5 0.0 0.00033 19.3 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5580) Dockerin_1 PF00404.18 KIY65364.1 - 0.0026 17.9 1.2 0.4 10.9 0.2 2.8 1 1 2 3 3 3 2 Dockerin type I domain UPF0154 PF03672.13 KIY65364.1 - 0.004 17.2 0.0 0.16 12.0 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0154) EF-hand_11 PF08976.11 KIY65364.1 - 0.0059 17.5 0.0 0.083 13.8 0.0 1.9 1 1 1 2 2 2 1 EF-hand domain S4_2 PF13275.6 KIY65364.1 - 0.031 14.1 0.1 0.062 13.1 0.0 1.5 2 0 0 2 2 2 0 S4 domain Caleosin PF05042.13 KIY65364.1 - 0.076 12.9 0.1 3.5 7.5 0.0 2.5 1 1 2 3 3 3 0 Caleosin related protein DUF4497 PF14924.6 KIY65364.1 - 0.086 13.3 0.0 0.11 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4497) MecA_N PF05223.11 KIY65364.1 - 0.1 12.9 0.1 1 9.6 0.0 1.9 1 1 1 2 2 2 0 NTF2-like N-terminal transpeptidase domain EFhand_Ca_insen PF08726.10 KIY65364.1 - 0.12 12.5 0.6 0.88 9.7 0.2 2.4 2 1 0 2 2 2 0 Ca2+ insensitive EF hand PAM2 PF07145.15 KIY65365.1 - 0.083 12.6 0.5 0.23 11.2 0.5 1.8 1 0 0 1 1 1 0 Ataxin-2 C-terminal region PHD PF00628.29 KIY65366.1 - 6.1e-08 32.4 5.8 1e-07 31.8 5.8 1.4 1 0 0 1 1 1 1 PHD-finger CFEM PF05730.11 KIY65366.1 - 0.0095 16.0 1.6 0.013 15.6 1.6 1.3 1 0 0 1 1 1 1 CFEM domain Clat_adaptor_s PF01217.20 KIY65367.1 - 4.6e-16 59.0 0.0 1.4e-15 57.5 0.0 1.7 1 1 0 1 1 1 1 Clathrin adaptor complex small chain DUF3835 PF12927.7 KIY65367.1 - 0.12 13.2 0.0 0.2 12.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3835) ING PF12998.7 KIY65368.1 - 6.3e-14 52.4 0.1 9.8e-14 51.8 0.1 1.2 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 KIY65368.1 - 7.1e-07 29.0 7.3 1.2e-06 28.3 7.3 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 KIY65368.1 - 0.0062 16.8 2.9 0.017 15.4 2.9 1.8 1 1 0 1 1 1 1 PHD-like zinc-binding domain zf-met PF12874.7 KIY65368.1 - 0.033 14.6 0.1 0.065 13.6 0.1 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type Mo25 PF08569.11 KIY65369.1 - 1.7e-132 441.8 6.5 1.9e-132 441.6 6.5 1.0 1 0 0 1 1 1 1 Mo25-like Condensin2nSMC PF12422.8 KIY65369.1 - 0.1 12.8 2.2 1.8 8.8 2.2 2.4 1 1 0 1 1 1 0 Condensin II non structural maintenance of chromosomes subunit DNA_methylase PF00145.17 KIY65370.1 - 2.5e-30 106.0 0.0 4.6e-25 88.7 0.0 2.9 2 1 0 2 2 2 2 C-5 cytosine-specific DNA methylase NmrA PF05368.13 KIY65373.1 - 1.1e-08 34.9 0.9 0.00061 19.4 0.1 2.7 2 1 0 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.6 KIY65373.1 - 1.6e-08 34.6 0.0 0.00017 21.5 0.0 2.3 2 0 0 2 2 2 2 NAD(P)H-binding Epimerase PF01370.21 KIY65373.1 - 0.00013 21.5 0.0 0.00082 18.9 0.0 2.2 1 1 1 3 3 3 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KIY65373.1 - 0.00048 19.3 0.0 0.0012 18.0 0.0 1.6 2 0 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KIY65373.1 - 0.0055 15.9 0.0 0.12 11.5 0.0 2.1 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KIY65373.1 - 0.006 16.0 0.0 0.0091 15.4 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Semialdhyde_dh PF01118.24 KIY65373.1 - 0.019 15.4 0.0 0.051 14.0 0.0 1.8 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 KIY65373.1 - 0.062 13.4 0.0 0.14 12.3 0.0 1.7 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_4 PF07993.12 KIY65373.1 - 0.067 12.3 0.0 0.14 11.3 0.0 1.5 1 0 0 1 1 1 0 Male sterility protein KR PF08659.10 KIY65373.1 - 0.13 12.1 0.0 0.37 10.7 0.0 1.6 1 1 0 1 1 1 0 KR domain MR_MLE_C PF13378.6 KIY65374.1 - 7e-54 182.7 0.0 9e-54 182.3 0.0 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KIY65374.1 - 2.3e-20 73.0 0.0 3.8e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Filament PF00038.21 KIY65375.1 - 0.0062 16.2 1.3 0.015 14.9 1.2 1.5 1 1 0 1 1 1 1 Intermediate filament protein CENP-Q PF13094.6 KIY65375.1 - 0.0097 16.1 1.4 0.5 10.6 0.8 2.4 1 1 1 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit Baculo_PEP_C PF04513.12 KIY65375.1 - 0.017 15.2 2.1 1.3 9.1 0.0 2.5 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Flagellin_N PF00669.20 KIY65375.1 - 0.075 13.1 2.7 0.16 12.1 2.7 1.5 1 0 0 1 1 1 0 Bacterial flagellin N-terminal helical region GARP PF16731.5 KIY65375.1 - 0.12 12.0 3.8 3.3 7.4 0.1 2.6 1 1 1 2 2 2 0 Glutamic acid/alanine-rich protein of Trypanosoma SKA2 PF16740.5 KIY65375.1 - 0.13 12.0 1.3 1.3 8.8 0.3 2.2 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 TACC_C PF05010.14 KIY65375.1 - 0.13 12.0 0.2 0.22 11.3 0.2 1.2 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal BAR_3_WASP_bdg PF10456.9 KIY65375.1 - 0.17 11.3 0.1 0.28 10.6 0.1 1.3 1 0 0 1 1 1 0 WASP-binding domain of Sorting nexin protein TPR_MLP1_2 PF07926.12 KIY65375.1 - 0.26 11.4 1.9 0.51 10.4 1.9 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein TBCC_N PF16752.5 KIY65375.1 - 0.29 11.6 1.2 6.2 7.3 0.1 2.5 1 1 1 2 2 2 0 Tubulin-specific chaperone C N-terminal domain ATG16 PF08614.11 KIY65375.1 - 2.7 8.1 10.6 0.084 13.1 2.3 2.5 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) SKA1 PF07160.12 KIY65375.1 - 4.4 7.1 6.6 1.7 8.5 0.3 2.6 2 1 1 3 3 3 0 Spindle and kinetochore-associated protein 1 adh_short_C2 PF13561.6 KIY65376.1 - 2.6e-58 197.3 0.2 3.2e-58 197.0 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIY65376.1 - 1.7e-46 158.2 0.9 2.1e-46 157.9 0.9 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIY65376.1 - 3e-10 40.3 1.3 4.6e-10 39.7 1.3 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KIY65376.1 - 3.2e-06 26.8 0.0 6e-06 25.9 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 KIY65376.1 - 0.022 14.2 0.0 0.03 13.7 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) DUF3455 PF11937.8 KIY65377.1 - 2.3e-26 93.1 0.0 2.9e-26 92.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) Oxidored_FMN PF00724.20 KIY65378.1 - 8.8e-34 117.3 0.0 1.1e-33 116.9 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Aldedh PF00171.22 KIY65379.1 - 2.6e-117 392.2 0.0 3e-117 392.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family F-box-like PF12937.7 KIY65380.1 - 5.8e-05 22.9 1.3 0.00018 21.4 1.3 1.9 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KIY65381.1 - 9e-09 35.1 0.3 1.6e-08 34.3 0.3 1.5 1 1 0 1 1 1 1 F-box-like HSA PF07529.13 KIY65382.1 - 1.4e-11 44.5 0.1 1.4e-11 44.5 0.1 4.9 6 0 0 6 6 6 1 HSA Myb_DNA-bind_6 PF13921.6 KIY65382.1 - 5.9e-07 29.6 0.0 2.2e-06 27.8 0.0 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KIY65382.1 - 0.0065 16.6 0.1 0.014 15.5 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain F-box-like PF12937.7 KIY65383.1 - 1.1e-10 41.2 2.2 2.6e-10 40.0 1.3 2.1 2 0 0 2 2 2 1 F-box-like FAD_binding_7 PF03441.14 KIY65384.1 - 1.7e-45 155.0 0.6 2.9e-45 154.2 0.6 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 KIY65384.1 - 2.5e-20 73.1 0.2 5e-20 72.1 0.2 1.5 1 0 0 1 1 1 1 DNA photolyase SOG2 PF10428.9 KIY65385.1 - 1.1e-93 315.2 8.0 1.1e-93 315.2 8.0 2.8 3 0 0 3 3 3 1 RAM signalling pathway protein LRR_8 PF13855.6 KIY65385.1 - 1.3e-18 66.5 13.8 2.8e-09 36.6 0.6 2.8 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 KIY65385.1 - 6e-09 36.0 1.9 5.8e-05 23.4 0.5 2.9 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KIY65385.1 - 0.0028 17.2 0.1 0.0062 16.1 0.1 1.5 1 0 0 1 1 1 1 Leucine-rich repeat zf-C2H2 PF00096.26 KIY65387.1 - 8.7e-11 41.7 14.5 5.2e-05 23.5 1.0 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 KIY65387.1 - 4e-10 39.3 9.6 0.0011 18.6 0.1 3.5 3 0 0 3 3 3 3 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 KIY65387.1 - 8.9e-09 35.5 13.5 0.00063 20.4 0.5 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KIY65387.1 - 5.9e-06 26.5 23.5 0.0054 17.1 0.1 4.3 4 0 0 4 4 4 2 Zinc-finger double domain zf-Di19 PF05605.12 KIY65387.1 - 0.0059 16.9 14.1 0.082 13.2 5.3 2.6 1 1 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 KIY65387.1 - 0.0069 16.7 6.2 0.38 11.1 0.2 2.4 1 1 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 KIY65387.1 - 0.018 15.4 0.0 0.047 14.1 0.0 1.7 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf_C2H2_ZHX PF18387.1 KIY65387.1 - 0.033 13.8 7.3 1.9 8.2 0.1 3.4 1 1 2 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_jaz PF12171.8 KIY65387.1 - 0.06 13.7 1.3 0.13 12.6 0.0 2.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Zn_Tnp_IS1595 PF12760.7 KIY65387.1 - 0.13 12.3 6.2 0.52 10.3 1.9 2.5 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-BED PF02892.15 KIY65387.1 - 0.18 11.9 7.5 0.13 12.3 1.0 2.5 2 0 0 2 2 2 0 BED zinc finger zinc_ribbon_9 PF14369.6 KIY65387.1 - 0.21 11.9 2.1 8.2 6.8 0.3 2.8 2 0 0 2 2 2 0 zinc-ribbon IBR PF01485.21 KIY65387.1 - 0.51 10.6 11.5 0.044 14.0 4.7 2.2 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain GAGA PF09237.11 KIY65387.1 - 0.71 9.7 5.0 0.85 9.5 0.0 2.7 1 1 2 3 3 3 0 GAGA factor Elf1 PF05129.13 KIY65387.1 - 1.7 8.8 8.1 7.4 6.7 0.1 2.8 1 1 2 3 3 3 0 Transcription elongation factor Elf1 like Zn-C2H2_12 PF18112.1 KIY65387.1 - 1.9 9.1 4.5 2.8 8.5 0.6 3.1 2 1 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain OrsD PF12013.8 KIY65387.1 - 2.2 8.8 12.4 0.76 10.2 0.8 3.1 1 1 2 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-nanos PF05741.13 KIY65387.1 - 4.4 7.6 8.3 8.3 6.7 2.1 2.6 1 1 0 2 2 2 0 Nanos RNA binding domain Ribosomal_L37ae PF01780.19 KIY65387.1 - 6 7.0 5.9 20 5.4 0.4 2.6 1 1 1 2 2 2 0 Ribosomal L37ae protein family PolC_DP2 PF03833.13 KIY65387.1 - 6.3 4.5 5.4 8.4 4.1 5.4 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Cu-oxidase_3 PF07732.15 KIY65388.1 - 2.1e-40 137.5 8.0 3.6e-40 136.7 2.1 3.2 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KIY65388.1 - 9.7e-36 122.5 4.1 2.4e-31 108.3 0.1 3.0 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 KIY65388.1 - 1.4e-34 119.5 0.0 2.6e-34 118.6 0.0 1.4 1 0 0 1 1 1 1 Multicopper oxidase Phosphoesterase PF04185.14 KIY65389.1 - 9.5e-31 107.3 5.6 1e-29 103.8 5.3 2.0 1 1 0 1 1 1 1 Phosphoesterase family Sulfatase PF00884.23 KIY65389.1 - 3.4e-05 23.4 0.8 5.4e-05 22.7 0.8 1.4 1 0 0 1 1 1 1 Sulfatase ABC_membrane PF00664.23 KIY65390.1 - 2.8e-62 210.9 29.0 1.1e-35 123.7 12.2 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KIY65390.1 - 2e-51 174.1 0.0 5.7e-31 107.9 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KIY65390.1 - 3.2e-09 36.5 2.7 0.0072 15.8 0.1 4.3 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KIY65390.1 - 2.4e-05 24.4 1.1 0.049 13.7 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 KIY65390.1 - 2.7e-05 23.8 0.4 0.16 11.8 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 KIY65390.1 - 8.5e-05 22.5 2.4 0.1 12.4 0.1 3.2 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KIY65390.1 - 0.00022 21.7 0.6 0.74 10.2 0.0 3.0 3 0 0 3 3 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KIY65390.1 - 0.00052 19.9 1.4 0.26 11.2 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase ATP_bind_1 PF03029.17 KIY65390.1 - 0.0013 18.6 1.3 12 5.5 0.0 3.6 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_30 PF13604.6 KIY65390.1 - 0.0049 16.6 0.8 3 7.5 0.2 2.7 3 0 0 3 3 2 2 AAA domain AAA_7 PF12775.7 KIY65390.1 - 0.0057 16.2 1.0 2.4 7.6 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_24 PF13479.6 KIY65390.1 - 0.0095 15.7 0.2 4.7 6.9 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 KIY65390.1 - 0.013 16.0 0.4 0.12 12.9 0.0 3.7 3 1 1 4 4 3 0 AAA domain TsaE PF02367.17 KIY65390.1 - 0.019 15.0 0.1 0.34 10.9 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 KIY65390.1 - 0.025 14.8 2.4 1.4 9.1 0.1 3.2 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.12 KIY65390.1 - 0.037 13.3 0.5 9.6 5.4 0.1 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_15 PF13175.6 KIY65390.1 - 0.038 13.7 4.7 2 8.1 0.0 3.1 2 1 1 3 3 3 0 AAA ATPase domain Roc PF08477.13 KIY65390.1 - 0.042 14.1 1.3 11 6.2 0.1 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_33 PF13671.6 KIY65390.1 - 0.049 13.8 1.3 4.5 7.4 0.0 3.1 3 0 0 3 3 3 0 AAA domain NACHT PF05729.12 KIY65390.1 - 0.06 13.3 1.9 0.28 11.1 0.2 2.7 3 0 0 3 3 3 0 NACHT domain AAA_25 PF13481.6 KIY65390.1 - 0.067 12.8 0.1 1.3 8.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 KIY65390.1 - 0.072 12.7 1.8 0.22 11.1 0.2 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TrwB_AAD_bind PF10412.9 KIY65390.1 - 0.14 11.1 1.3 5.1 5.9 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain DEAD PF00270.29 KIY65390.1 - 0.25 11.1 0.4 41 3.9 0.0 3.1 3 0 0 3 3 3 0 DEAD/DEAH box helicase NB-ARC PF00931.22 KIY65390.1 - 0.29 10.3 1.6 14 4.8 0.2 2.5 2 0 0 2 2 2 0 NB-ARC domain DUF87 PF01935.17 KIY65390.1 - 1.1 9.3 8.2 0.56 10.2 0.7 3.5 3 1 1 4 4 4 0 Helicase HerA, central domain DUF4337 PF14235.6 KIY65390.1 - 3.7 7.7 6.3 5.1 7.2 3.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) RNA_pol_Rpc4 PF05132.14 KIY65390.1 - 4.1 7.8 5.3 2.7 8.4 1.5 2.2 2 0 0 2 2 2 0 RNA polymerase III RPC4 Fungal_trans PF04082.18 KIY65392.1 - 2.2e-14 53.2 0.1 2.7e-14 52.8 0.1 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain SMI1_KNR4 PF09346.10 KIY65393.1 - 2.2e-25 89.6 0.0 5.2e-25 88.4 0.0 1.6 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) Tup_N PF08581.10 KIY65394.1 - 0.0024 18.1 2.9 0.0043 17.3 1.3 2.2 1 1 1 2 2 2 1 Tup N-terminal CENP-F_leu_zip PF10473.9 KIY65394.1 - 0.03 14.4 10.8 0.055 13.5 10.8 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fzo_mitofusin PF04799.13 KIY65394.1 - 0.037 13.6 3.5 0.071 12.7 3.5 1.4 1 0 0 1 1 1 0 fzo-like conserved region YscO PF07321.12 KIY65394.1 - 0.039 13.9 11.5 0.1 12.6 11.5 1.7 1 1 0 1 1 1 0 Type III secretion protein YscO PI3K_P85_iSH2 PF16454.5 KIY65394.1 - 0.093 12.3 7.3 0.15 11.7 7.3 1.3 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain GAS PF13851.6 KIY65394.1 - 0.45 9.8 9.1 0.73 9.1 9.1 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Pox_A_type_inc PF04508.12 KIY65394.1 - 0.54 10.2 3.4 4.5 7.3 0.6 2.9 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat F-box-like PF12937.7 KIY65395.1 - 3.7e-09 36.3 2.8 1.2e-08 34.7 2.8 2.0 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KIY65395.1 - 0.1 12.5 2.6 0.42 10.6 0.1 2.9 2 0 0 2 2 2 0 F-box domain ABC_tran_CTD PF16326.5 KIY65395.1 - 0.18 12.1 2.4 0.45 10.8 2.4 1.6 1 0 0 1 1 1 0 ABC transporter C-terminal domain LRR_4 PF12799.7 KIY65395.1 - 1.7 9.2 8.7 2.9 8.4 0.2 4.0 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KIY65396.1 - 2.6e-05 24.0 4.3 2.6e-05 24.0 4.3 2.6 2 1 0 2 2 2 1 F-box-like F-box PF00646.33 KIY65396.1 - 0.009 15.9 0.2 0.06 13.3 0.2 2.6 1 0 0 1 1 1 1 F-box domain VHS PF00790.19 KIY65399.1 - 1.8e-37 128.3 0.6 4.7e-37 127.0 0.0 1.9 2 0 0 2 2 2 1 VHS domain FYVE PF01363.21 KIY65399.1 - 4.6e-17 61.9 7.4 7.4e-17 61.3 7.4 1.3 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.20 KIY65399.1 - 9.7e-07 28.3 9.5 0.00093 19.0 2.8 2.8 2 0 0 2 2 2 2 Ubiquitin interaction motif FYVE_2 PF02318.16 KIY65399.1 - 0.016 15.4 5.5 0.033 14.4 5.5 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger C1_1 PF00130.22 KIY65399.1 - 0.018 14.9 3.5 0.018 14.9 3.5 1.7 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) GAT PF03127.14 KIY65399.1 - 0.019 15.3 0.0 0.043 14.1 0.0 1.7 1 0 0 1 1 1 0 GAT domain DZR PF12773.7 KIY65399.1 - 0.27 11.3 9.1 3.8 7.6 0.7 2.4 1 1 2 3 3 3 0 Double zinc ribbon Joubert PF15392.6 KIY65399.1 - 0.47 10.1 4.1 0.8 9.4 4.1 1.3 1 0 0 1 1 1 0 Joubert syndrome-associated RNA_pol_Rpb1_1 PF04997.12 KIY65400.1 - 1.4e-107 359.7 0.0 2e-107 359.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 KIY65400.1 - 3.6e-104 347.9 0.1 5.2e-104 347.4 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KIY65400.1 - 4.2e-74 248.3 0.0 7.4e-74 247.5 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 KIY65400.1 - 1.2e-64 217.7 0.2 2.4e-64 216.7 0.2 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_7 PF04990.12 KIY65400.1 - 6.4e-47 158.9 0.1 1.7e-46 157.6 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_3 PF04983.18 KIY65400.1 - 1.1e-46 158.7 0.0 3.1e-46 157.2 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 KIY65400.1 - 9.8e-37 125.2 0.0 2.1e-36 124.1 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 KIY65400.1 - 7.8e-14 51.2 251.9 0.024 15.0 9.8 15.5 13 2 0 15 15 15 12 RNA polymerase Rpb1 C-terminal repeat Pkinase PF00069.25 KIY65401.1 - 4e-37 128.0 0.0 5e-37 127.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY65401.1 - 6.3e-16 58.4 0.0 3.2e-15 56.1 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIY65401.1 - 0.033 13.0 0.0 0.044 12.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase LppA PF16708.5 KIY65401.1 - 0.1 12.5 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Lipoprotein confined to pathogenic Mycobacterium GST_N_3 PF13417.6 KIY65402.1 - 1.4e-09 38.2 0.0 2.4e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KIY65402.1 - 4.4e-09 36.5 0.0 6.8e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KIY65402.1 - 1e-07 32.2 0.0 1.7e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KIY65402.1 - 0.00024 21.1 0.1 0.00048 20.1 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KIY65402.1 - 0.00081 19.6 0.1 0.005 17.0 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KIY65402.1 - 0.0028 18.2 0.0 0.0054 17.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 KIY65402.1 - 0.0094 16.2 0.0 0.017 15.3 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin GST_C_3 PF14497.6 KIY65402.1 - 0.11 12.6 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain F-box-like PF12937.7 KIY65404.1 - 8.4e-08 32.0 0.7 1.9e-07 30.8 0.7 1.7 1 0 0 1 1 1 1 F-box-like F-box_5 PF18511.1 KIY65404.1 - 0.18 11.4 0.9 20 4.8 0.0 2.9 3 0 0 3 3 3 0 F-box YlbD_coat PF14071.6 KIY65405.1 - 0.056 13.7 1.9 0.26 11.5 1.9 1.9 1 1 0 1 1 1 0 Putative coat protein Coq4 PF05019.13 KIY65407.1 - 0.18 11.1 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 ADH_zinc_N PF00107.26 KIY65408.1 - 6.1e-20 71.5 0.0 1.1e-19 70.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KIY65408.1 - 2.8e-17 62.6 0.0 5.4e-17 61.7 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 KIY65408.1 - 2.2e-07 32.0 0.0 3.9e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DNA_ligase_OB_2 PF14743.6 KIY65408.1 - 0.02 14.9 0.1 0.06 13.4 0.0 1.8 2 0 0 2 2 2 0 DNA ligase OB-like domain TrkA_N PF02254.18 KIY65408.1 - 0.029 14.6 0.0 0.067 13.5 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Pkinase PF00069.25 KIY65409.1 - 5.1e-23 81.8 0.0 6.9e-23 81.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KIY65409.1 - 7.7e-09 35.8 0.5 0.00046 20.2 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KIY65409.1 - 1.3e-07 31.2 0.0 1.6e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KIY65409.1 - 0.0044 16.4 0.1 0.0086 15.5 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KIY65409.1 - 0.0076 15.9 0.0 0.01 15.4 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 KIY65409.1 - 0.03 13.1 0.2 0.042 12.6 0.2 1.1 1 0 0 1 1 1 0 Fungal protein kinase Fructosamin_kin PF03881.14 KIY65409.1 - 0.16 11.1 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 Fructosamine kinase DUF3237 PF11578.8 KIY65410.1 - 0.024 14.5 0.1 0.1 12.4 0.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3237) zf-H2C2_5 PF13909.6 KIY65413.1 - 0.021 14.6 0.1 0.052 13.3 0.1 1.6 1 0 0 1 1 1 0 C2H2-type zinc-finger domain Aldo_ket_red PF00248.21 KIY65414.1 - 4.4e-77 259.2 0.0 5e-77 259.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ADH_zinc_N PF00107.26 KIY65415.1 - 3.2e-20 72.4 0.0 6e-20 71.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KIY65415.1 - 5.9e-13 48.7 0.0 1.8e-11 43.9 0.0 2.5 2 1 0 2 2 2 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 KIY65415.1 - 1.5e-07 32.5 0.0 2.7e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.21 KIY65415.1 - 0.021 14.5 1.6 0.034 13.9 1.6 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase zf-MYND PF01753.18 KIY65416.1 - 0.00022 21.3 13.1 0.00056 19.9 13.1 1.8 1 0 0 1 1 1 1 MYND finger CH PF00307.31 KIY65416.1 - 0.15 12.3 0.0 0.42 10.8 0.0 1.8 1 0 0 1 1 1 0 Calponin homology (CH) domain Phe_tRNA-synt_N PF02912.18 KIY65416.1 - 0.23 11.4 0.1 0.5 10.3 0.1 1.5 1 0 0 1 1 1 0 Aminoacyl tRNA synthetase class II, N-terminal domain Neuralized PF07177.12 KIY65419.1 - 0.2 11.7 0.0 0.35 10.9 0.0 1.4 1 0 0 1 1 1 0 Neuralized SRF-TF PF00319.18 KIY65421.1 - 7.7e-21 73.3 0.0 1.2e-20 72.8 0.0 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF1387 PF07139.11 KIY65421.1 - 0.97 9.1 4.8 1.3 8.6 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) CDC45 PF02724.14 KIY65421.1 - 1 7.6 4.9 1.2 7.3 4.9 1.0 1 0 0 1 1 1 0 CDC45-like protein Rrn6 PF10214.9 KIY65421.1 - 1.2 7.5 7.6 1.5 7.2 7.6 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF842 PF05811.13 KIY65422.1 - 0.0026 17.4 0.5 0.0031 17.2 0.5 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) zf-H2C2_5 PF13909.6 KIY65422.1 - 0.034 13.9 0.0 0.09 12.5 0.0 1.7 1 0 0 1 1 1 0 C2H2-type zinc-finger domain PX PF00787.24 KIY65422.1 - 0.047 13.7 0.1 0.055 13.4 0.1 1.1 1 0 0 1 1 1 0 PX domain zf-C2H2 PF00096.26 KIY65422.1 - 0.33 11.5 4.4 14 6.3 2.6 2.8 2 1 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIY65422.1 - 1 10.4 6.3 2 9.5 0.0 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger Lactamase_B_2 PF12706.7 KIY65423.1 - 4.1e-32 111.3 0.2 6.6e-32 110.7 0.2 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KIY65423.1 - 3.2e-11 43.4 0.0 4.4e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KIY65423.1 - 0.047 13.7 0.1 0.22 11.5 0.0 2.0 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily Sensor PF13796.6 KIY65424.1 - 0.28 11.2 19.4 0.037 14.1 12.1 2.1 1 1 1 2 2 2 0 Putative sensor SLATT_1 PF18181.1 KIY65424.1 - 0.55 10.2 4.0 12 5.8 1.5 2.5 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 NPC1_N PF16414.5 KIY65425.1 - 4.8e-81 271.9 9.0 6.9e-81 271.4 9.0 1.2 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus Patched PF02460.18 KIY65425.1 - 5.2e-65 220.0 5.7 1.7e-36 125.7 0.1 3.1 3 0 0 3 3 3 3 Patched family Sterol-sensing PF12349.8 KIY65425.1 - 8.7e-44 149.0 15.9 4.3e-24 85.1 0.4 3.6 3 0 0 3 3 3 2 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.19 KIY65425.1 - 1.5e-06 26.3 4.7 3e-06 25.2 4.7 1.4 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family Folate_rec PF03024.14 KIY65425.1 - 0.00074 19.4 1.0 0.0016 18.3 1.0 1.5 1 0 0 1 1 1 1 Folate receptor family SIR2 PF02146.17 KIY65426.1 - 1.6e-35 122.6 0.1 8.3e-34 117.0 0.1 2.8 1 1 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 KIY65426.1 - 0.016 14.9 0.0 0.17 11.6 0.0 2.1 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain zinc_ribbon_5 PF13719.6 KIY65426.1 - 0.12 12.2 0.9 5.9 6.7 0.3 2.7 2 0 0 2 2 2 0 zinc-ribbon domain PNTB PF02233.16 KIY65426.1 - 0.26 10.1 0.0 1 8.2 0.0 1.7 2 0 0 2 2 2 0 NAD(P) transhydrogenase beta subunit zinc_ribbon_4 PF13717.6 KIY65426.1 - 0.28 11.1 2.6 1 9.3 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain MRP-S26 PF14943.6 KIY65427.1 - 0.0035 17.3 0.0 0.0052 16.7 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosome subunit S26 Kelch_4 PF13418.6 KIY65428.1 - 4.9e-15 55.3 7.8 9.1e-05 22.4 0.0 6.4 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_6 PF13964.6 KIY65428.1 - 1.2e-14 54.0 7.5 5.7e-05 23.2 0.1 6.7 7 0 0 7 7 7 3 Kelch motif Kelch_2 PF07646.15 KIY65428.1 - 5.2e-10 38.9 1.8 0.092 12.8 0.0 6.3 6 0 0 6 6 6 2 Kelch motif Kelch_5 PF13854.6 KIY65428.1 - 1e-09 38.2 1.7 0.075 13.1 0.0 5.6 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.6 KIY65428.1 - 4.7e-09 36.3 7.9 0.021 15.1 0.0 5.6 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_1 PF01344.25 KIY65428.1 - 3.4e-07 29.7 6.4 0.0021 17.6 0.0 5.5 6 0 0 6 6 6 2 Kelch motif zf-MYND PF01753.18 KIY65428.1 - 0.0015 18.5 11.3 0.0034 17.5 11.3 1.6 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KIY65428.1 - 0.005 17.1 14.2 0.011 16.1 14.2 1.5 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding TPR_1 PF00515.28 KIY65428.1 - 0.077 12.9 0.1 0.46 10.4 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat ABC_membrane PF00664.23 KIY65429.1 - 4e-57 193.9 31.7 1.2e-29 103.9 13.4 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KIY65429.1 - 4.2e-53 179.5 0.1 1e-29 103.8 0.1 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KIY65429.1 - 3.2e-10 39.8 0.4 0.056 12.9 0.0 4.2 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KIY65429.1 - 1.4e-08 34.8 0.2 0.0055 16.8 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.6 KIY65429.1 - 7.4e-07 29.3 0.5 0.062 13.1 0.0 3.0 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KIY65429.1 - 9.7e-07 28.4 0.0 0.039 13.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KIY65429.1 - 1.8e-06 28.5 1.0 0.054 13.9 0.4 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 KIY65429.1 - 6.2e-06 26.9 0.0 0.16 12.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.23 KIY65429.1 - 1.9e-05 24.8 0.1 0.034 14.2 0.0 2.5 2 0 0 2 2 2 2 Dynamin family RsgA_GTPase PF03193.16 KIY65429.1 - 2.4e-05 24.3 0.0 0.17 11.7 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_30 PF13604.6 KIY65429.1 - 9.4e-05 22.2 0.6 0.55 9.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.18 KIY65429.1 - 9.7e-05 21.8 0.0 0.16 11.3 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_25 PF13481.6 KIY65429.1 - 0.00058 19.5 0.1 0.016 14.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 KIY65429.1 - 0.0012 18.6 0.0 0.23 11.1 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain Roc PF08477.13 KIY65429.1 - 0.0016 18.7 0.1 2.8 8.2 0.0 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase DUF87 PF01935.17 KIY65429.1 - 0.0028 17.8 0.9 1.2 9.2 0.0 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_22 PF13401.6 KIY65429.1 - 0.0033 17.7 1.2 3.3 8.0 0.1 3.2 3 0 0 3 3 3 1 AAA domain AAA_7 PF12775.7 KIY65429.1 - 0.0089 15.6 0.0 2.5 7.6 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region Zeta_toxin PF06414.12 KIY65429.1 - 0.0091 15.3 0.3 1.4 8.2 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin NB-ARC PF00931.22 KIY65429.1 - 0.017 14.3 0.1 3 6.9 0.0 2.5 3 0 0 3 3 2 0 NB-ARC domain NACHT PF05729.12 KIY65429.1 - 0.017 15.0 0.1 5.7 6.8 0.0 2.5 2 0 0 2 2 2 0 NACHT domain IstB_IS21 PF01695.17 KIY65429.1 - 0.021 14.6 0.2 44 3.7 0.0 3.5 3 0 0 3 3 3 0 IstB-like ATP binding protein DUF815 PF05673.13 KIY65429.1 - 0.022 13.9 0.5 3.4 6.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) SbcCD_C PF13558.6 KIY65429.1 - 0.03 14.6 0.0 4.6 7.6 0.0 3.0 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit ATP-synt_ab PF00006.25 KIY65429.1 - 0.032 13.9 0.0 9.3 5.8 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain TrwB_AAD_bind PF10412.9 KIY65429.1 - 0.042 12.7 0.3 1.7 7.4 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain cobW PF02492.19 KIY65429.1 - 0.058 13.0 0.6 4.6 6.8 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 KIY65429.1 - 0.09 11.7 0.4 6.1 5.7 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MobB PF03205.14 KIY65429.1 - 0.13 12.1 0.2 11 5.9 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B TsaE PF02367.17 KIY65429.1 - 0.16 11.9 0.1 21 5.1 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 KIY65429.1 - 0.47 11.0 1.4 37 4.9 0.1 3.0 2 1 1 3 3 3 0 AAA domain NAD_binding_1 PF00175.21 KIY65430.1 - 2e-11 44.5 0.0 2.4e-10 41.0 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KIY65430.1 - 9.1e-10 38.8 0.0 1.9e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KIY65430.1 - 3.7e-09 36.9 0.0 2.4e-05 24.5 0.0 2.1 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 KIY65430.1 - 0.092 13.0 0.0 0.32 11.2 0.0 1.9 2 0 0 2 2 2 0 Siderophore-interacting FAD-binding domain Sedlin_N PF04628.13 KIY65431.1 - 6.6e-35 120.1 0.1 5e-34 117.2 0.1 1.9 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 KIY65431.1 - 1.4e-06 28.3 0.0 2.7e-06 27.4 0.1 1.5 2 0 0 2 2 2 1 Sybindin-like family LapA_dom PF06305.11 KIY65432.1 - 0.029 14.2 0.0 0.062 13.1 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain SKG6 PF08693.10 KIY65432.1 - 0.21 11.0 0.9 0.5 9.8 0.9 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Rhomboid PF01694.22 KIY65433.1 - 3.6e-23 82.2 7.6 5.1e-23 81.7 6.7 1.7 2 0 0 2 2 2 1 Rhomboid family DUF1751 PF08551.10 KIY65433.1 - 0.0044 17.6 0.1 0.01 16.4 0.0 1.7 1 1 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) CDP-OH_P_transf PF01066.21 KIY65434.1 - 1.1e-12 48.5 0.2 3.5e-12 46.9 0.2 1.8 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase BOP1NT PF08145.12 KIY65435.1 - 9.8e-104 346.9 8.6 1.3e-103 346.4 8.6 1.2 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 KIY65435.1 - 4e-22 78.1 8.5 1.2e-06 29.1 0.0 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY65435.1 - 8.4e-07 29.2 0.2 2.8 8.3 0.0 4.2 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Actin PF00022.19 KIY65436.1 - 6.2e-115 384.1 0.0 7e-115 383.9 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KIY65436.1 - 1.4e-06 27.3 0.0 0.0074 15.1 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein HNH_2 PF13391.6 KIY65437.1 - 5.6e-06 26.4 0.0 1.1e-05 25.4 0.0 1.6 1 1 0 1 1 1 1 HNH endonuclease RELT PF12606.8 KIY65437.1 - 0.6 9.1 2.5 4 6.5 1.4 2.2 2 0 0 2 2 2 0 Tumour necrosis factor receptor superfamily member 19 GAS2 PF02187.17 KIY65438.1 - 5.9e-12 45.5 0.2 1.9e-11 43.9 0.2 1.8 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Beta-lactamase PF00144.24 KIY65440.1 - 1.7e-46 159.0 0.0 3.3e-46 158.1 0.0 1.3 1 1 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.6 KIY65440.1 - 0.0053 16.4 0.0 0.11 12.0 0.0 2.1 2 0 0 2 2 2 1 Beta-lactamase enzyme family Peptidase_S11 PF00768.20 KIY65440.1 - 0.12 11.7 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase Glyco_hydro_43 PF04616.14 KIY65441.1 - 9.7e-25 87.4 0.2 1.4e-24 86.9 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_43 PF04616.14 KIY65442.1 - 5.9e-24 84.9 0.6 7.7e-24 84.5 0.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Ribosomal_S11 PF00411.19 KIY65443.1 - 4.1e-12 46.5 0.0 5.1e-10 39.7 0.0 2.3 2 0 0 2 2 2 2 Ribosomal protein S11 UCR_UQCRX_QCR9 PF05365.12 KIY65444.1 - 7.6e-25 86.6 4.2 8.4e-25 86.5 4.2 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Flavokinase PF01687.17 KIY65445.1 - 5.3e-32 110.4 0.0 6.7e-32 110.1 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase Trp_oprn_chp PF09534.10 KIY65446.1 - 0.045 13.5 4.9 0.65 9.8 2.1 2.1 1 1 1 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) TFIIA PF03153.13 KIY65447.1 - 0.0093 16.0 3.9 0.013 15.5 3.9 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit GREB1 PF15782.5 KIY65447.1 - 3.4 4.7 12.9 4.2 4.4 12.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Lin-8 PF03353.15 KIY65447.1 - 7.2 6.1 8.1 12 5.4 8.1 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF1479 PF07350.12 KIY65448.1 - 1.9e-134 448.5 0.0 2.3e-134 448.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.13 KIY65448.1 - 0.0017 18.7 0.6 0.64 10.2 0.3 3.0 2 2 0 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) Diphthamide_syn PF01866.17 KIY65449.1 - 1.4e-89 300.5 0.0 1.1e-55 189.2 0.0 2.1 2 0 0 2 2 2 2 Putative diphthamide synthesis protein Glyco_hydro_16 PF00722.21 KIY65450.1 - 2.2e-22 79.4 0.3 3.1e-22 78.9 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF1080 PF06439.11 KIY65450.1 - 0.057 13.5 0.2 0.25 11.5 0.2 1.8 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1080) Lipase_GDSL_2 PF13472.6 KIY65451.1 - 2.4e-11 44.4 4.7 3e-11 44.1 4.7 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KIY65451.1 - 1.5e-07 31.6 0.1 1.9e-07 31.2 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase GPI-anchored PF10342.9 KIY65452.1 - 0.096 13.5 0.0 0.13 13.1 0.0 1.3 1 0 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Myc_target_1 PF15179.6 KIY65454.1 - 0.028 14.3 1.3 0.046 13.6 0.1 1.9 2 0 0 2 2 2 0 Myc target protein 1 DUF2052 PF09747.9 KIY65454.1 - 4.2 7.4 10.0 1.3 9.2 3.1 2.2 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Spore_coat_CotO PF14153.6 KIY65454.1 - 5.2 7.0 9.7 0.71 9.8 2.4 2.3 2 0 0 2 2 2 0 Spore coat protein CotO TIMELESS_C PF05029.13 KIY65454.1 - 6.3 5.8 12.3 0.071 12.3 4.7 1.5 2 0 0 2 2 2 0 Timeless protein C terminal region Zn_clus PF00172.18 KIY65455.1 - 0.037 14.1 1.2 0.037 14.1 1.2 2.8 2 1 1 3 3 3 0 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-CCCH_4 PF18044.1 KIY65456.1 - 4.4e-07 29.6 8.7 0.0023 17.7 1.0 2.3 2 0 0 2 2 2 2 CCCH-type zinc finger Torus PF16131.5 KIY65456.1 - 2.4e-05 25.0 6.7 0.0021 18.7 0.7 2.5 1 1 1 2 2 2 2 Torus domain zf_CCCH_4 PF18345.1 KIY65456.1 - 3.4e-05 23.7 14.2 0.00034 20.6 2.5 2.3 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH PF00642.24 KIY65456.1 - 8.7e-05 22.3 7.8 0.0015 18.4 1.6 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 KIY65456.1 - 0.00022 21.4 1.3 0.00039 20.6 1.3 1.3 1 0 0 1 1 1 1 Zinc-finger containing family DJ-1_PfpI PF01965.24 KIY65457.1 - 4.4e-16 59.1 0.0 8.7e-16 58.2 0.0 1.5 1 1 0 1 1 1 1 DJ-1/PfpI family RNase_H PF00075.24 KIY65458.1 - 0.014 15.5 0.0 0.031 14.4 0.0 1.5 1 0 0 1 1 1 0 RNase H Glyco_hydro_18 PF00704.28 KIY65459.1 - 9.3e-11 42.0 2.1 6.2e-10 39.3 0.1 1.9 1 1 1 2 2 2 2 Glycosyl hydrolases family 18 GHL6 PF14871.6 KIY65459.1 - 0.062 13.5 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 DUF1955 PF09205.10 KIY65460.1 - 0.065 13.0 0.1 0.09 12.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1955) Kdo PF06293.14 KIY65465.1 - 0.01 15.2 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KIY65465.1 - 0.23 10.8 0.0 0.37 10.1 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain BNR PF02012.20 KIY65468.1 - 2 8.8 4.2 0.54 10.5 0.6 2.2 2 0 0 2 2 2 0 BNR/Asp-box repeat Beta-lactamase PF00144.24 KIY65470.1 - 2.2e-33 115.9 0.0 4.3e-33 114.9 0.0 1.3 1 1 0 1 1 1 1 Beta-lactamase WD40 PF00400.32 KIY65471.1 - 2.1e-57 189.7 19.9 3.8e-08 33.9 0.7 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.10 KIY65471.1 - 3.1e-24 85.1 1.8 5.3e-24 84.3 1.8 1.4 1 0 0 1 1 1 1 Tup N-terminal ANAPC4_WD40 PF12894.7 KIY65471.1 - 6.6e-21 74.4 0.6 0.00023 21.4 0.0 6.2 2 2 5 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KIY65471.1 - 2.1e-09 37.1 0.3 0.0071 15.7 0.0 5.1 6 1 1 7 7 7 2 WD40-like domain Ge1_WD40 PF16529.5 KIY65471.1 - 6.4e-08 31.9 1.1 1.2 8.1 0.0 5.8 2 2 4 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 KIY65471.1 - 0.00096 18.6 0.3 8.2 5.7 0.0 3.5 3 1 1 4 4 4 2 Neuroblastoma-amplified sequence, N terminal Tropomyosin PF00261.20 KIY65471.1 - 0.0026 17.2 0.8 0.0037 16.7 0.8 1.1 1 0 0 1 1 1 1 Tropomyosin eIF2A PF08662.11 KIY65471.1 - 0.015 15.2 0.0 6.9 6.5 0.0 3.2 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KIY65471.1 - 0.14 10.7 0.2 7.5 5.1 0.0 3.5 2 1 3 5 5 5 0 Nucleoporin Nup120/160 F-box-like PF12937.7 KIY65474.1 - 4.2e-06 26.6 0.3 1.2e-05 25.1 0.3 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY65474.1 - 0.39 10.6 6.6 4.4 7.3 0.8 3.3 3 0 0 3 3 3 0 F-box domain Pec_lyase_C PF00544.19 KIY65475.1 - 6.1e-10 39.0 9.2 7.9e-09 35.4 9.2 2.2 1 1 0 1 1 1 1 Pectate lyase STE3 PF02076.15 KIY65476.1 - 5.8e-45 153.7 17.8 7.4e-45 153.4 17.8 1.1 1 0 0 1 1 1 1 Pheromone A receptor DUF898 PF05987.13 KIY65476.1 - 0.55 9.2 9.0 2.7 7.0 9.0 2.1 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF898) RNase_H PF00075.24 KIY65477.1 - 0.13 12.4 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 RNase H FA_desaturase PF00487.24 KIY65478.1 - 7e-19 68.6 26.7 1.7e-18 67.4 26.7 1.6 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 KIY65478.1 - 0.0051 17.0 0.1 0.0097 16.1 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) zf-C2H2_4 PF13894.6 KIY65479.1 - 6.9e-07 29.6 10.7 0.00079 20.1 1.1 4.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KIY65479.1 - 7.5e-06 26.1 9.9 0.0051 17.2 1.0 3.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KIY65479.1 - 0.00045 20.5 7.7 0.021 15.2 1.0 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2HE PF16278.5 KIY65479.1 - 0.0021 18.5 1.2 0.0044 17.4 0.2 2.1 1 1 1 2 2 2 1 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_8 PF15909.5 KIY65479.1 - 0.032 14.5 1.0 0.032 14.5 1.0 2.0 2 0 0 2 2 2 0 C2H2-type zinc ribbon zf-Di19 PF05605.12 KIY65479.1 - 0.038 14.3 3.7 0.055 13.8 2.5 1.9 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 KIY65479.1 - 0.098 12.7 3.7 0.58 10.2 0.1 2.8 3 0 0 3 3 3 0 C2H2-type zinc finger Zn_clus PF00172.18 KIY65479.1 - 0.14 12.4 7.6 0.49 10.6 6.7 2.3 1 1 1 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_jaz PF12171.8 KIY65479.1 - 0.22 11.9 10.6 0.98 9.8 0.2 4.4 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KIY65479.1 - 5.4 7.5 18.0 1.3 9.5 0.2 4.6 6 0 0 6 6 6 0 Zinc-finger of C2H2 type PAP2 PF01569.21 KIY65480.1 - 2.3e-27 95.4 2.1 6.7e-27 93.9 2.1 1.7 1 1 0 1 1 1 1 PAP2 superfamily p450 PF00067.22 KIY65482.1 - 1.4e-66 225.2 0.0 3.3e-66 223.9 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 PPR_2 PF13041.6 KIY65484.1 - 7.6e-12 45.2 1.0 6.7e-07 29.4 0.1 4.7 4 1 1 5 5 5 3 PPR repeat family PPR_long PF17177.4 KIY65484.1 - 2.2e-09 37.0 0.8 0.033 13.6 0.0 3.6 3 0 0 3 3 3 3 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 KIY65484.1 - 2.7e-06 27.2 4.9 21 5.6 0.0 7.7 8 1 0 8 8 8 1 PPR repeat PPR_1 PF12854.7 KIY65484.1 - 1.4e-05 24.7 0.0 0.073 12.8 0.0 4.8 5 1 0 5 5 5 1 PPR repeat PPR_3 PF13812.6 KIY65484.1 - 4.3e-05 23.5 0.0 0.0019 18.3 0.0 3.1 3 0 0 3 3 3 1 Pentatricopeptide repeat domain TPR_14 PF13428.6 KIY65484.1 - 0.83 10.6 16.1 43 5.3 0.0 7.8 7 2 2 9 9 9 0 Tetratricopeptide repeat Nrap_D4 PF17405.2 KIY65485.1 - 1.4e-50 171.6 0.0 2.6e-50 170.7 0.0 1.5 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D2 PF17403.2 KIY65485.1 - 5.7e-40 136.6 0.0 2.5e-39 134.5 0.0 2.1 3 0 0 3 3 3 1 Nrap protein PAP/OAS-like domain Nrap_D3 PF17404.2 KIY65485.1 - 1.4e-39 135.8 0.0 3.8e-39 134.3 0.0 1.8 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap_D5 PF17406.2 KIY65485.1 - 8.5e-35 119.9 0.0 1.4e-33 115.9 0.0 2.5 2 0 0 2 2 2 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D6 PF17407.2 KIY65485.1 - 8.2e-34 116.7 0.0 2.3e-33 115.3 0.0 1.8 2 0 0 2 2 2 1 Nrap protein domain 6 Nrap PF03813.14 KIY65485.1 - 4e-31 108.1 0.0 7.1e-31 107.3 0.0 1.4 1 0 0 1 1 1 1 Nrap protein domain 1 Rep_fac-A_C PF08646.10 KIY65487.1 - 1.9e-42 144.4 0.6 3e-38 130.8 0.0 2.4 2 0 0 2 2 2 2 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 KIY65487.1 - 1.3e-35 121.3 1.0 1.9e-33 114.3 0.1 3.0 3 0 0 3 3 3 1 Replication protein A OB domain tRNA_anti-codon PF01336.25 KIY65487.1 - 4.5e-16 58.6 0.3 3.9e-12 46.0 0.0 3.5 3 0 0 3 3 3 1 OB-fold nucleic acid binding domain Rep-A_N PF04057.12 KIY65487.1 - 7e-12 45.3 0.1 1.6e-11 44.1 0.1 1.6 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain DUF223 PF02721.14 KIY65487.1 - 0.00032 20.9 0.1 0.00072 19.8 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF223 DUF4539 PF15072.6 KIY65487.1 - 0.0061 16.6 0.0 0.15 12.1 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4539) tRNA_anti_2 PF13742.6 KIY65487.1 - 0.0075 16.4 0.2 0.42 10.8 0.0 2.6 3 0 0 3 3 3 1 OB-fold nucleic acid binding domain BTB PF00651.31 KIY65487.1 - 0.027 14.7 0.1 0.13 12.5 0.0 2.2 3 0 0 3 3 3 0 BTB/POZ domain CDC24_OB3 PF17244.2 KIY65487.1 - 0.036 13.8 1.9 7.1 6.3 0.1 3.3 3 1 1 4 4 4 0 Cell division control protein 24, OB domain 3 DUF5521 PF17659.1 KIY65487.1 - 0.049 11.5 0.0 0.1 10.5 0.0 1.4 2 0 0 2 2 2 0 Family of unknown function (DUF5521) OrfB_Zn_ribbon PF07282.11 KIY65487.1 - 0.13 12.2 0.6 0.28 11.1 0.6 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain IDO PF01231.18 KIY65488.1 - 5.5e-117 391.2 0.0 6.5e-117 391.0 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase ECH_2 PF16113.5 KIY65489.1 - 6.8e-103 344.7 0.2 3.9e-75 253.4 0.0 2.4 2 1 1 3 3 3 2 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 KIY65489.1 - 2.9e-26 92.3 0.0 2.4e-25 89.3 0.0 2.0 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase CAP_GLY PF01302.25 KIY65490.1 - 1.1e-19 70.2 0.2 1.9e-19 69.4 0.2 1.4 1 0 0 1 1 1 1 CAP-Gly domain LRR_8 PF13855.6 KIY65490.1 - 1.5e-08 34.2 13.8 0.038 13.8 0.0 5.1 3 3 3 6 6 6 5 Leucine rich repeat LRR_9 PF14580.6 KIY65490.1 - 7.1e-07 28.9 2.2 0.00025 20.6 0.1 3.2 1 1 3 4 4 4 3 Leucine-rich repeat LRR_4 PF12799.7 KIY65490.1 - 5.9e-05 23.3 17.8 2.4 8.7 0.1 6.6 6 1 1 7 7 7 5 Leucine Rich repeats (2 copies) RRM_1 PF00076.22 KIY65491.1 - 3.6e-26 90.8 0.0 3.6e-13 49.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KIY65491.1 - 0.015 15.4 0.0 0.04 14.0 0.0 1.8 1 1 0 1 1 1 0 RNA recognition motif RRM_3 PF08777.11 KIY65491.1 - 0.047 13.7 0.0 0.61 10.2 0.0 2.1 2 0 0 2 2 2 0 RNA binding motif Nup35_RRM_2 PF14605.6 KIY65491.1 - 0.087 12.8 0.0 0.81 9.7 0.0 2.2 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Aminotran_5 PF00266.19 KIY65492.1 - 1.2e-91 307.5 0.1 1.4e-91 307.3 0.1 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KIY65492.1 - 3.5e-07 29.8 0.1 4.7e-07 29.4 0.1 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 KIY65492.1 - 0.0004 19.0 0.1 0.00058 18.5 0.1 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DUF1681 PF07933.14 KIY65493.1 - 3.3e-50 169.7 0.0 3.8e-50 169.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) Lipase_GDSL PF00657.22 KIY65494.1 - 3.3e-05 24.0 0.0 8.3e-05 22.7 0.0 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 KIY65494.1 - 9.5e-05 22.9 0.0 0.00017 22.1 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family CSN8_PSD8_EIF3K PF10075.9 KIY65495.1 - 1.6e-20 73.6 0.3 3.4e-19 69.2 0.3 2.1 1 1 0 1 1 1 1 CSN8/PSMD8/EIF3K family Pro_3_hydrox_C PF05373.11 KIY65495.1 - 0.0091 16.1 0.0 0.018 15.1 0.0 1.5 1 0 0 1 1 1 1 L-proline 3-hydroxylase, C-terminal AAA PF00004.29 KIY65496.1 - 6.5e-85 282.2 0.0 7.6e-42 142.9 0.0 2.8 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KIY65496.1 - 8.2e-22 76.8 0.4 5.8e-12 45.2 0.2 2.5 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 KIY65496.1 - 5.6e-13 49.6 0.6 5.5e-08 33.4 0.0 3.4 2 1 0 3 3 3 2 AAA ATPase domain RuvB_N PF05496.12 KIY65496.1 - 1.6e-12 47.5 0.0 0.0005 19.9 0.0 3.6 3 1 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KIY65496.1 - 4.1e-11 43.0 0.0 3.3e-05 23.9 0.0 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KIY65496.1 - 2.6e-10 40.7 0.0 0.00053 20.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KIY65496.1 - 7.6e-09 36.0 0.6 0.00013 22.3 0.0 4.2 2 2 0 3 3 3 1 AAA domain AAA_33 PF13671.6 KIY65496.1 - 4.6e-08 33.3 0.0 0.00021 21.4 0.0 2.8 2 1 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 KIY65496.1 - 1.1e-07 31.7 0.0 0.00047 19.9 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein TIP49 PF06068.13 KIY65496.1 - 9.9e-07 28.3 0.0 0.019 14.2 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_14 PF13173.6 KIY65496.1 - 1.4e-05 25.1 0.0 0.019 15.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain Rad17 PF03215.15 KIY65496.1 - 0.00027 20.9 0.4 0.4 10.6 0.0 3.3 2 2 1 3 3 3 1 Rad17 P-loop domain TsaE PF02367.17 KIY65496.1 - 0.00034 20.6 0.0 0.18 11.8 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 KIY65496.1 - 0.00043 19.7 0.1 0.3 10.4 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 KIY65496.1 - 0.00063 19.1 0.0 0.025 13.8 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_7 PF12775.7 KIY65496.1 - 0.00068 19.2 0.0 0.6 9.6 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_18 PF13238.6 KIY65496.1 - 0.00079 20.0 0.0 0.0091 16.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KIY65496.1 - 0.00083 19.0 2.1 2.4 7.7 0.1 4.2 2 2 2 4 4 4 1 AAA domain RNA_helicase PF00910.22 KIY65496.1 - 0.0011 19.3 0.0 0.29 11.5 0.0 2.4 2 0 0 2 2 2 1 RNA helicase AAA_11 PF13086.6 KIY65496.1 - 0.0012 18.7 0.0 0.05 13.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.11 KIY65496.1 - 0.0031 17.4 0.0 1.9 8.4 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KIY65496.1 - 0.0059 16.5 0.1 0.2 11.5 0.0 3.2 3 1 1 4 4 4 1 NACHT domain AAA_28 PF13521.6 KIY65496.1 - 0.0074 16.5 0.0 0.17 12.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 KIY65496.1 - 0.0081 15.9 0.0 0.11 12.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 KIY65496.1 - 0.017 14.9 0.1 1.6 8.4 0.0 3.2 4 1 0 4 4 2 0 Sigma-54 interaction domain PhoH PF02562.16 KIY65496.1 - 0.017 14.6 0.2 0.48 9.8 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein Bac_DnaA PF00308.18 KIY65496.1 - 0.024 14.5 0.0 0.17 11.7 0.0 2.3 2 2 0 2 2 2 0 Bacterial dnaA protein AAA_30 PF13604.6 KIY65496.1 - 0.025 14.3 0.0 0.16 11.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 KIY65496.1 - 0.028 14.2 0.0 0.41 10.4 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DAP3 PF10236.9 KIY65496.1 - 0.028 13.6 0.0 0.11 11.6 0.0 1.8 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_19 PF13245.6 KIY65496.1 - 0.05 13.9 0.0 0.58 10.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 KIY65496.1 - 0.12 11.7 0.0 22 4.3 0.0 2.7 2 0 0 2 2 2 0 KaiC AFG1_ATPase PF03969.16 KIY65496.1 - 0.12 11.2 0.0 0.76 8.6 0.0 2.0 2 0 0 2 2 2 0 AFG1-like ATPase IPT PF01745.16 KIY65496.1 - 0.18 11.1 0.1 1.2 8.5 0.1 2.1 2 0 0 2 2 2 0 Isopentenyl transferase MscS_porin PF12795.7 KIY65497.1 - 0.031 13.8 5.5 0.045 13.3 5.5 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain DUF4715 PF15835.5 KIY65497.1 - 0.068 13.2 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4715) GDA1_CD39 PF01150.17 KIY65497.1 - 0.085 11.5 0.1 0.12 11.0 0.1 1.1 1 0 0 1 1 1 0 GDA1/CD39 (nucleoside phosphatase) family NAD_binding_10 PF13460.6 KIY65498.1 - 7.7e-06 25.9 0.0 1e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Pyr_redox_2 PF07992.14 KIY65499.1 - 5.1e-11 42.3 0.0 7e-06 25.5 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Malic_M PF03949.15 KIY65499.1 - 0.013 14.8 0.1 0.023 14.0 0.1 1.3 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain DAO PF01266.24 KIY65499.1 - 0.016 14.8 0.1 0.15 11.7 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KIY65499.1 - 0.02 14.9 0.0 0.25 11.3 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.17 KIY65499.1 - 0.17 11.1 0.1 0.3 10.3 0.1 1.3 1 0 0 1 1 1 0 Thi4 family EURL PF06937.11 KIY65500.1 - 0.068 12.6 0.0 0.099 12.0 0.0 1.1 1 0 0 1 1 1 0 EURL protein 6PGD PF00393.19 KIY65501.1 - 7.6e-126 419.3 0.0 9.3e-126 419.1 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KIY65501.1 - 1.4e-50 171.5 0.0 2.1e-50 171.0 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KIY65501.1 - 0.0045 17.5 0.1 0.0091 16.6 0.1 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 KIY65501.1 - 0.1 11.9 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CoatB PF10389.9 KIY65501.1 - 3.5 7.5 6.3 18 5.2 1.5 2.5 2 0 0 2 2 2 0 Bacteriophage coat protein B Oxysterol_BP PF01237.18 KIY65502.1 - 1.8e-112 375.9 0.7 6.7e-112 374.0 0.7 1.8 1 1 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.6 KIY65502.1 - 1e-17 64.2 1.3 1.4e-17 63.7 0.1 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 KIY65502.1 - 1.9e-08 34.8 0.2 6.3e-08 33.1 0.0 2.0 2 0 0 2 2 2 1 PH domain Glucosamine_iso PF01182.20 KIY65503.1 - 4.7e-72 242.5 0.0 5.4e-72 242.3 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Aminotran_4 PF01063.19 KIY65504.1 - 7.8e-29 101.1 0.0 1.5e-28 100.2 0.0 1.4 1 1 0 1 1 1 1 Amino-transferase class IV DSPc PF00782.20 KIY65505.1 - 1.8e-21 76.3 0.0 3e-20 72.4 0.0 2.4 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KIY65505.1 - 0.012 15.1 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Sortilin-Vps10 PF15902.5 KIY65506.1 - 1.8e-12 46.8 9.9 0.0071 15.2 0.1 6.0 4 2 0 5 5 5 4 Sortilin, neurotensin receptor 3, CBM_1 PF00734.18 KIY65506.1 - 2.1e-11 43.6 10.3 5.2e-11 42.3 10.3 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain BNR_6 PF15899.5 KIY65506.1 - 0.00057 19.7 9.7 0.18 12.0 0.2 5.9 5 0 0 5 5 5 1 BNR-Asp box repeat BNR_2 PF13088.6 KIY65506.1 - 0.0039 16.5 18.0 1 8.6 0.0 6.5 4 2 1 5 5 5 3 BNR repeat-like domain BNR PF02012.20 KIY65506.1 - 0.0048 16.7 46.6 0.57 10.4 0.9 10.9 11 0 0 11 11 11 3 BNR/Asp-box repeat DUF2452 PF10504.9 KIY65506.1 - 0.12 11.8 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2452) adh_short PF00106.25 KIY65507.1 - 1.2e-31 109.8 2.2 1.8e-31 109.1 2.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIY65507.1 - 1.2e-25 90.5 3.0 2.5e-25 89.4 3.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIY65507.1 - 4.9e-07 29.8 1.3 7.2e-07 29.3 1.1 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KIY65507.1 - 5.1e-06 26.1 0.2 6.9e-06 25.7 0.2 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KIY65507.1 - 6.7e-05 22.9 0.4 0.00016 21.6 0.4 1.6 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 KIY65507.1 - 0.02 14.0 2.1 0.16 11.0 0.2 2.1 2 0 0 2 2 2 0 RmlD substrate binding domain DUF1776 PF08643.10 KIY65507.1 - 0.03 13.7 0.1 0.66 9.3 0.0 2.0 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.15 KIY65507.1 - 0.09 11.9 0.4 0.14 11.3 0.2 1.4 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KIY65507.1 - 0.11 11.9 0.2 0.13 11.6 0.2 1.3 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase Sortilin-Vps10 PF15902.5 KIY65508.1 - 1.5e-12 47.0 7.4 0.0036 16.2 0.1 6.4 6 1 0 6 6 6 4 Sortilin, neurotensin receptor 3, BNR_6 PF15899.5 KIY65508.1 - 1e-05 25.1 17.5 0.31 11.2 0.1 7.9 8 0 0 8 8 8 3 BNR-Asp box repeat BNR PF02012.20 KIY65508.1 - 0.00014 21.4 37.1 1.3 9.3 0.1 9.7 9 0 0 9 9 9 4 BNR/Asp-box repeat BNR_2 PF13088.6 KIY65508.1 - 0.063 12.6 15.7 16 4.7 0.0 6.8 3 2 2 6 6 6 0 BNR repeat-like domain DUF2452 PF10504.9 KIY65508.1 - 0.27 10.7 0.0 0.49 9.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2452) DWNN PF08783.11 KIY65510.1 - 3.1e-27 94.7 0.1 6.2e-27 93.7 0.1 1.5 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.6 KIY65510.1 - 1.8e-10 40.4 6.5 3.7e-10 39.4 6.5 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 KIY65510.1 - 2.3e-07 30.6 1.7 5.1e-07 29.5 1.7 1.6 1 0 0 1 1 1 1 Zinc knuckle U-box PF04564.15 KIY65510.1 - 0.0018 18.4 0.0 0.0066 16.6 0.0 1.9 2 0 0 2 2 2 1 U-box domain zf-CCHC_3 PF13917.6 KIY65510.1 - 0.0041 17.0 0.5 0.012 15.6 0.5 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 KIY65510.1 - 0.035 13.8 0.8 0.035 13.8 0.8 1.9 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger zf_C2H2_10 PF18414.1 KIY65510.1 - 0.035 13.6 0.8 0.035 13.6 0.8 2.0 2 0 0 2 2 2 0 C2H2 type zinc-finger zf-C3HC4_3 PF13920.6 KIY65510.1 - 0.43 10.5 11.2 0.051 13.4 5.1 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KIY65510.1 - 1.9 8.4 13.8 0.11 12.4 7.3 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIY65510.1 - 2.7 8.4 13.3 0.067 13.5 6.8 1.7 2 0 0 2 2 2 0 Ring finger domain zf_UBZ PF18439.1 KIY65510.1 - 4.2 7.1 8.0 2.5 7.8 0.1 2.9 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-RING_5 PF14634.6 KIY65510.1 - 4.3 7.4 12.8 0.44 10.5 7.1 2.1 2 0 0 2 2 2 0 zinc-RING finger domain zf-Tim10_DDP PF02953.15 KIY65511.1 - 1.5e-22 79.0 1.2 1.5e-22 79.0 1.2 1.4 1 1 1 2 2 2 1 Tim10/DDP family zinc finger Acyltransferase PF01553.21 KIY65512.1 - 4.2e-20 71.7 0.0 6.3e-20 71.2 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 KIY65512.1 - 2.2e-07 30.9 0.0 5.3e-05 23.2 0.0 2.4 2 0 0 2 2 2 2 Acyltransferase C-terminus Aa_trans PF01490.18 KIY65513.1 - 6e-32 110.8 34.4 6.9e-32 110.7 34.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein CoxIIa PF08113.11 KIY65513.1 - 0.0034 17.1 1.5 0.025 14.4 1.5 2.6 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IIa family F-box PF00646.33 KIY65514.1 - 0.07 13.0 0.1 0.43 10.5 0.1 2.4 1 0 0 1 1 1 0 F-box domain DUF4248 PF14053.6 KIY65514.1 - 0.091 12.8 0.1 0.18 11.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4248) F-box-like PF12937.7 KIY65514.1 - 1.1 9.2 6.6 0.24 11.3 0.3 3.3 5 0 0 5 5 5 0 F-box-like Hydrolase_4 PF12146.8 KIY65515.1 - 8.7e-06 25.2 0.0 0.00094 18.5 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KIY65515.1 - 0.0028 18.3 9.3 0.0033 18.0 0.0 3.4 3 1 0 3 3 3 2 Alpha/beta hydrolase family Aconitase PF00330.20 KIY65516.1 - 1.2e-151 505.8 0.0 1.5e-151 505.5 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KIY65516.1 - 1.2e-33 116.2 0.0 2.1e-33 115.4 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF5453 PF17534.2 KIY65517.1 - 0.19 11.7 8.9 0.061 13.3 5.0 2.1 2 1 1 3 3 3 0 Family of unknown function (DUF5453) adh_short_C2 PF13561.6 KIY65518.1 - 1e-54 185.6 2.1 1.3e-54 185.3 2.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIY65518.1 - 1.8e-52 177.7 1.9 2.3e-52 177.3 1.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIY65518.1 - 9.8e-08 32.1 1.0 1.4e-07 31.6 1.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KIY65518.1 - 0.021 14.3 0.1 0.064 12.7 0.1 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 KIY65518.1 - 0.037 13.4 0.1 0.072 12.4 0.1 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain CAP PF00188.26 KIY65519.1 - 4.2e-20 72.9 2.8 6.7e-20 72.2 2.8 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Ribonuc_red_lgC PF02867.15 KIY65519.1 - 0.069 11.7 0.1 0.091 11.3 0.1 1.1 1 0 0 1 1 1 0 Ribonucleotide reductase, barrel domain ubiquitin PF00240.23 KIY65521.1 - 1.5e-170 553.2 25.4 1.9e-33 114.0 0.5 5.0 5 0 0 5 5 5 5 Ubiquitin family Rad60-SLD PF11976.8 KIY65521.1 - 2.6e-78 257.8 27.8 4.3e-15 55.3 0.6 5.0 5 0 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KIY65521.1 - 3e-28 98.1 12.9 0.00064 20.1 0.1 6.9 5 5 0 5 5 5 5 Ubiquitin-like domain TBK1_ULD PF18396.1 KIY65521.1 - 1.6e-19 69.6 5.6 0.047 13.6 0.0 5.2 5 0 0 5 5 5 5 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 KIY65521.1 - 1.2e-17 64.0 4.5 0.16 12.1 0.0 6.0 5 4 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 KIY65521.1 - 1.7e-17 63.5 11.5 0.063 13.6 0.1 5.1 5 0 0 5 5 5 5 Ubiquitin-like domain DUF2407 PF10302.9 KIY65521.1 - 5.3e-16 59.1 2.2 0.55 10.8 0.0 5.2 1 1 0 5 5 5 5 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 KIY65521.1 - 3.1e-12 46.6 0.7 1.6 8.5 0.0 5.1 1 1 4 5 5 5 5 Silencing defective 2 N-terminal ubiquitin domain Methyltrans_RNA PF04452.14 KIY65521.1 - 3.7e-09 36.3 1.8 1.4 8.2 0.0 4.2 4 0 0 4 4 4 4 RNA methyltransferase Ubiquitin_4 PF18036.1 KIY65521.1 - 1.2e-07 31.7 32.7 21 5.2 0.2 9.9 10 0 0 10 10 10 0 Ubiquitin-like domain Big_7 PF17957.1 KIY65521.1 - 1.6e-07 32.0 0.6 41 5.0 0.0 5.1 5 0 0 5 5 5 0 Bacterial Ig domain DUF2870 PF11069.8 KIY65521.1 - 1.9e-07 31.4 0.0 40 4.7 0.0 5.8 5 0 0 5 5 5 0 Protein of unknown function (DUF2870) TmoB PF06234.12 KIY65521.1 - 4.7e-07 29.8 0.1 40 4.4 0.0 5.8 5 0 0 5 5 5 0 Toluene-4-monooxygenase system protein B (TmoB) DUF3861 PF12977.7 KIY65521.1 - 5.8e-07 29.6 5.6 18 5.6 0.0 5.2 5 0 0 5 5 5 0 Domain of Unknown Function with PDB structure (DUF3861) ACT_5 PF13710.6 KIY65521.1 - 1.2e-06 28.2 6.5 15 5.5 0.0 5.3 5 0 0 5 5 5 0 ACT domain UDP-g_GGTase PF06427.11 KIY65521.1 - 4.3e-06 26.8 6.0 9.6 6.4 0.0 4.9 5 0 0 5 5 5 0 UDP-glucose:Glycoprotein Glucosyltransferase DUF969 PF06149.12 KIY65521.1 - 2.3e-05 23.9 0.1 29 4.0 0.0 4.8 5 0 0 5 5 5 0 Protein of unknown function (DUF969) ACT_4 PF13291.6 KIY65521.1 - 6e-05 23.6 2.2 97 3.7 0.0 5.2 5 0 0 5 5 5 0 ACT domain DUF493 PF04359.14 KIY65521.1 - 0.00037 21.0 0.1 1.9e+02 2.7 0.0 4.9 5 0 0 5 5 5 0 Protein of unknown function (DUF493) ORF11CD3 PF10549.9 KIY65521.1 - 0.0007 19.7 0.0 1.2e+02 2.9 0.0 5.1 5 0 0 5 5 5 0 ORF11CD3 domain ProRS-C_2 PF09181.10 KIY65521.1 - 0.008 16.3 8.5 85 3.4 0.1 5.1 5 0 0 5 5 5 0 Prolyl-tRNA synthetase, C-terminal FlgD_ig PF13860.6 KIY65521.1 - 0.052 13.4 13.5 57 3.7 0.1 5.3 5 0 0 5 5 5 0 FlgD Ig-like domain Tash_PEST PF07708.11 KIY65521.1 - 0.19 11.9 36.0 8 6.8 1.4 5.3 5 0 0 5 5 5 0 Tash protein PEST motif Phage_sheath_1N PF17481.2 KIY65521.1 - 0.46 11.0 12.5 1e+02 3.5 0.1 4.9 1 1 1 3 3 3 0 Phage tail sheath protein beta-sandwich domain YcgR_2 PF12945.7 KIY65521.1 - 2.4 8.4 7.6 3.2e+02 1.6 0.0 4.8 5 0 0 5 5 5 0 Flagellar protein YcgR PI3K_p85B PF02192.16 KIY65521.1 - 3 7.6 12.6 1.3e+02 2.5 0.1 5.1 5 0 0 5 5 5 0 PI3-kinase family, p85-binding domain Cnl2_NKP2 PF09447.10 KIY65521.1 - 3.1 8.0 14.4 1.3e+02 2.8 0.1 5.3 5 0 0 5 5 5 0 Cnl2/NKP2 family protein Ribosomal_S4e PF00900.20 KIY65521.1 - 5.8 6.9 11.7 1.7e+02 2.2 0.1 5.6 5 0 0 5 5 5 0 Ribosomal family S4e N2227 PF07942.12 KIY65522.1 - 2.5e-94 315.5 0.0 3.1e-94 315.2 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.6 KIY65522.1 - 4.2e-08 33.2 0.0 1.6e-07 31.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIY65522.1 - 4.1e-06 27.4 0.0 0.0002 21.9 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIY65522.1 - 2.4e-05 25.0 0.0 0.00032 21.4 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIY65522.1 - 0.0028 17.5 0.0 0.059 13.2 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIY65522.1 - 0.0036 18.0 0.0 0.1 13.3 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain FAD_binding_6 PF00970.24 KIY65523.1 - 3e-33 114.1 0.0 4.8e-33 113.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KIY65523.1 - 1.4e-32 112.5 0.0 2.1e-32 112.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 KIY65523.1 - 0.0008 19.6 0.0 0.011 15.9 0.0 2.1 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 KIY65523.1 - 0.21 11.8 0.0 0.39 10.9 0.0 1.5 1 1 0 1 1 1 0 Siderophore-interacting FAD-binding domain LRR_4 PF12799.7 KIY65524.1 - 4.7e-08 33.2 3.3 0.48 10.9 0.0 7.3 6 2 2 8 8 8 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KIY65524.1 - 0.00026 20.8 2.8 4.1 7.7 0.0 6.6 7 0 0 7 7 7 1 Leucine Rich repeat OmpA PF00691.20 KIY65526.1 - 0.029 14.8 0.0 0.029 14.7 0.0 1.0 1 0 0 1 1 1 0 OmpA family Phage_integrase PF00589.22 KIY65528.1 - 1.9e-06 27.8 0.0 4.4e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Phage integrase family PSP1 PF04468.12 KIY65529.1 - 5e-31 106.8 0.8 8.3e-31 106.1 0.8 1.4 1 0 0 1 1 1 1 PSP1 C-terminal conserved region IBR PF01485.21 KIY65530.1 - 2.6e-07 30.7 18.6 2.6e-05 24.4 7.2 4.1 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain TRAF6_Z2 PF18048.1 KIY65530.1 - 0.54 10.4 0.1 0.54 10.4 0.1 3.6 4 0 0 4 4 4 0 TNF receptor-associated factor 6 zinc finger 2 Rad50_zn_hook PF04423.14 KIY65530.1 - 2.6 7.9 9.8 3.2 7.7 2.1 2.8 2 1 0 2 2 2 0 Rad50 zinc hook motif IBR PF01485.21 KIY65531.1 - 0.0001 22.5 7.0 0.0001 22.5 7.0 3.6 4 0 0 4 4 4 2 IBR domain, a half RING-finger domain zf-RING_14 PF17978.1 KIY65531.1 - 0.016 15.6 1.9 0.016 15.6 1.9 2.5 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain DUF4428 PF14471.6 KIY65531.1 - 0.024 14.6 3.5 0.062 13.2 3.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) zinc_ribbon_9 PF14369.6 KIY65531.1 - 0.2 12.0 0.1 0.2 12.0 0.1 3.7 4 0 0 4 4 4 0 zinc-ribbon Cornichon PF03311.14 KIY65532.1 - 4.2 7.7 6.7 3.5 8.0 0.0 2.9 3 1 0 3 3 3 0 Cornichon protein ATP_bind_1 PF03029.17 KIY65534.1 - 1e-72 244.8 0.0 1.2e-72 244.6 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein KTI12 PF08433.10 KIY65534.1 - 0.082 12.3 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_33 PF13671.6 KIY65534.1 - 0.12 12.5 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain CLP1_P PF16575.5 KIY65534.1 - 0.13 12.1 0.0 0.25 11.1 0.0 1.6 1 1 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop DEAD PF00270.29 KIY65535.1 - 9.1e-17 61.4 0.0 1.7e-16 60.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIY65535.1 - 3.3e-14 53.2 0.1 1.4e-13 51.1 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 KIY65535.1 - 2.6e-09 37.7 0.1 9.4e-09 35.9 0.1 2.1 1 0 0 1 1 1 1 RecQ zinc-binding ResIII PF04851.15 KIY65535.1 - 7.3e-05 22.8 0.0 0.00023 21.2 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KIY65535.1 - 0.22 11.8 2.2 0.88 9.8 1.2 2.5 2 1 0 2 2 2 0 AAA domain DUF4315 PF14193.6 KIY65535.1 - 1.2 9.2 10.0 2.3 8.3 6.4 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4315) FlxA PF14282.6 KIY65535.1 - 1.7 8.7 10.9 1.6 8.8 6.6 2.5 2 0 0 2 2 2 0 FlxA-like protein Spc24 PF08286.11 KIY65535.1 - 8.7 6.6 7.5 2.3 8.5 2.3 2.4 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 CPSF_A PF03178.15 KIY65538.1 - 1.9e-77 260.8 0.0 2.9e-77 260.1 0.0 1.3 1 0 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.9 KIY65538.1 - 1.8e-19 69.8 0.0 2.8e-19 69.1 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term PTP_N PF12453.8 KIY65538.1 - 0.5 10.1 2.5 15 5.4 0.4 2.8 2 0 0 2 2 2 0 Protein tyrosine phosphatase N terminal Toxin_GhoT_OrtT PF10753.9 KIY65539.1 - 0.00039 20.6 2.6 51 4.2 0.0 4.9 5 0 0 5 5 5 4 Toxin GhoT_OrtT Lyase_1 PF00206.20 KIY65539.1 - 0.00069 19.1 0.2 23 4.2 0.0 3.8 2 2 2 4 4 4 4 Lyase DUF3328 PF11807.8 KIY65540.1 - 3.5e-45 154.5 0.3 4.1e-45 154.2 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Rbsn PF11464.8 KIY65541.1 - 0.12 12.2 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 Rabenosyn Rab binding domain Sel1 PF08238.12 KIY65544.1 - 4.7e-13 49.3 15.0 1.8e-06 28.4 0.2 5.5 5 0 0 5 5 5 3 Sel1 repeat TPR_8 PF13181.6 KIY65544.1 - 0.0032 17.5 0.2 0.053 13.8 0.0 3.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 KIY65544.1 - 0.0036 17.3 2.4 0.0068 16.4 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KIY65544.1 - 0.0059 16.4 0.0 0.02 14.7 0.0 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.6 KIY65544.1 - 0.66 10.7 2.2 42 5.1 0.2 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat 2-oxoacid_dh PF00198.23 KIY65545.1 - 3.7e-79 265.5 0.1 5e-79 265.0 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KIY65545.1 - 1.5e-18 66.4 1.2 2.8e-18 65.5 1.2 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 KIY65545.1 - 3.7e-05 23.5 0.0 0.0091 15.8 0.0 2.4 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_3 PF13437.6 KIY65545.1 - 0.00019 22.1 0.1 0.08 13.6 0.0 2.4 1 1 1 2 2 2 2 HlyD family secretion protein GCV_H PF01597.19 KIY65545.1 - 0.00027 20.8 0.4 0.00056 19.8 0.4 1.5 1 0 0 1 1 1 1 Glycine cleavage H-protein HlyD_D23 PF16576.5 KIY65545.1 - 0.011 15.0 0.1 0.064 12.5 0.0 1.9 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion RnfC_N PF13375.6 KIY65545.1 - 0.015 15.3 0.1 0.042 13.8 0.1 1.8 1 1 0 1 1 1 0 RnfC Barrel sandwich hybrid domain eIF3_subunit PF08597.10 KIY65545.1 - 1.2 9.0 14.0 1.9 8.4 14.0 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Mitofilin PF09731.9 KIY65545.1 - 2.1 7.1 10.2 2.7 6.7 10.2 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein RR_TM4-6 PF06459.12 KIY65545.1 - 8.5 6.1 8.3 12 5.6 8.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Homoserine_dh PF00742.19 KIY65546.1 - 7.2e-49 166.0 0.0 9.4e-49 165.7 0.0 1.1 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 KIY65546.1 - 1.7e-21 77.0 0.0 2.6e-21 76.5 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.24 KIY65546.1 - 0.00043 20.7 0.0 0.0012 19.3 0.0 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DUF3142 PF11340.8 KIY65546.1 - 0.052 13.4 0.0 0.1 12.4 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3142) NCE101 PF11654.8 KIY65546.1 - 0.096 12.4 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 Non-classical export protein 1 F-box-like PF12937.7 KIY65547.1 - 0.0077 16.1 4.3 0.081 12.8 4.3 2.6 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KIY65547.1 - 0.01 15.7 2.4 0.017 15.0 0.5 2.5 2 1 0 2 2 2 0 F-box domain YCII PF03795.14 KIY65548.1 - 1.1e-07 32.1 0.0 1.4e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 YCII-related domain DUF1786 PF08735.10 KIY65548.1 - 0.069 12.4 0.0 0.069 12.4 0.0 1.0 1 0 0 1 1 1 0 Putative pyruvate format-lyase activating enzyme (DUF1786) ECH_1 PF00378.20 KIY65549.1 - 6.7e-84 281.1 0.1 8.1e-84 280.8 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KIY65549.1 - 3e-36 125.6 0.2 1.4e-32 113.5 0.1 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 KIY65549.1 - 0.0023 17.9 0.1 0.056 13.4 0.0 2.2 2 0 0 2 2 2 1 Peptidase family S49 QCR10 PF09796.9 KIY65550.1 - 0.17 12.0 0.2 0.37 10.9 0.1 1.7 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Pkinase_fungal PF17667.1 KIY65552.1 - 1.5e-19 70.1 0.0 2.2e-19 69.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KIY65552.1 - 0.00011 22.2 0.0 0.00019 21.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KIY65552.1 - 0.0032 16.9 0.0 0.0051 16.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KIY65552.1 - 0.0053 16.4 0.0 0.008 15.8 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 KIY65552.1 - 0.034 13.1 0.0 0.046 12.6 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain EcKinase PF02958.20 KIY65552.1 - 0.15 11.4 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase PCI PF01399.27 KIY65553.1 - 3.6e-06 27.4 1.3 0.0024 18.3 0.0 3.7 3 0 0 3 3 3 2 PCI domain PEMT PF04191.13 KIY65554.1 - 4.9e-34 116.9 2.6 9.9e-34 115.9 2.6 1.5 1 0 0 1 1 1 1 Phospholipid methyltransferase DUF3925 PF13063.6 KIY65554.1 - 1.9 8.8 4.9 4.5 7.6 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3925) TauD PF02668.16 KIY65555.1 - 4.5e-53 180.8 0.3 6.5e-53 180.2 0.3 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 KIY65555.1 - 7.9e-09 36.0 0.0 1.7e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF971) CsiD PF08943.10 KIY65555.1 - 0.011 14.9 0.0 0.032 13.4 0.0 1.6 1 1 0 1 1 1 0 CsiD DUF2399 PF09664.10 KIY65555.1 - 0.15 11.9 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2399) RRM_1 PF00076.22 KIY65556.1 - 2.2e-08 33.8 0.0 3.5e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CBP_GIL PF10995.8 KIY65556.1 - 0.091 11.4 0.0 0.12 11.0 0.0 1.1 1 0 0 1 1 1 0 Cellulose biosynthesis GIL ICMT PF04140.14 KIY65557.1 - 2.1e-10 40.9 0.1 3.1e-09 37.1 0.0 2.2 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family ERG4_ERG24 PF01222.17 KIY65557.1 - 2.3e-08 33.2 0.0 3.9e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family PEMT PF04191.13 KIY65557.1 - 5e-07 30.1 0.1 5.6e-06 26.7 0.1 2.1 1 1 1 2 2 2 1 Phospholipid methyltransferase RRM_1 PF00076.22 KIY65558.1 - 2.1e-10 40.3 0.0 0.00026 20.7 0.0 3.2 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KIY65558.1 - 3.2e-06 27.2 0.0 0.0022 18.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif SF3b10 PF07189.11 KIY65561.1 - 2.1e-30 104.6 0.0 2.6e-30 104.4 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) Sugar_tr PF00083.24 KIY65562.1 - 2.4e-88 297.0 18.9 2.8e-88 296.8 18.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY65562.1 - 7.7e-24 84.3 29.0 5.8e-22 78.1 19.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Nepo_coat_N PF03689.15 KIY65565.1 - 0.056 13.4 0.1 0.068 13.1 0.1 1.1 1 0 0 1 1 1 0 Nepovirus coat protein, N-terminal domain DEAD PF00270.29 KIY65566.1 - 4.4e-44 150.3 0.7 4.4e-44 150.3 0.7 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIY65566.1 - 4.2e-33 114.0 0.5 1.8e-31 108.7 0.1 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIY65566.1 - 3.9e-06 27.0 0.0 7.2e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KIY65566.1 - 0.00013 22.4 0.4 0.0037 17.6 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KIY65566.1 - 0.00076 19.2 0.0 0.0013 18.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 KIY65566.1 - 0.096 12.2 0.1 0.13 11.8 0.1 1.3 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 KIY65566.1 - 0.11 12.8 1.1 0.36 11.1 0.3 2.3 2 1 0 2 2 2 0 AAA domain Flavi_DEAD PF07652.14 KIY65566.1 - 0.11 12.4 0.1 0.46 10.4 0.1 2.2 1 1 0 1 1 1 0 Flavivirus DEAD domain Tubulin PF00091.25 KIY65567.1 - 6.6e-59 199.4 0.0 9.7e-59 198.9 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KIY65567.1 - 3e-34 117.9 0.1 7.4e-34 116.6 0.0 1.7 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KIY65567.1 - 0.002 18.5 0.8 0.0043 17.3 0.0 1.9 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain DUF1117 PF06547.12 KIY65567.1 - 0.1 13.2 0.1 0.24 12.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1117) SKN1 PF03935.15 KIY65569.1 - 1.8e-187 623.7 2.1 2.3e-187 623.4 2.1 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) SAD_SRA PF02182.17 KIY65570.1 - 1.4e-48 164.5 0.0 1.6e-48 164.3 0.0 1.0 1 0 0 1 1 1 1 SAD/SRA domain Peptidase_S32 PF05579.13 KIY65571.1 - 0.011 14.9 0.2 0.019 14.2 0.2 1.3 1 0 0 1 1 1 0 Equine arteritis virus serine endopeptidase S32 F-box-like PF12937.7 KIY65572.1 - 6.8e-07 29.1 1.6 2.4e-06 27.3 1.6 2.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY65572.1 - 0.0048 16.7 0.1 0.016 15.1 0.1 1.9 1 0 0 1 1 1 1 F-box domain F-box-like_2 PF13013.6 KIY65572.1 - 0.0053 16.7 0.2 0.077 13.0 0.0 2.5 2 1 0 2 2 2 1 F-box-like domain TSC22 PF01166.18 KIY65572.1 - 0.06 13.7 0.1 0.13 12.5 0.1 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family LRR_4 PF12799.7 KIY65572.1 - 0.06 13.8 0.6 9.8 6.8 0.0 4.1 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) DASH_Dad2 PF08654.10 KIY65572.1 - 0.14 12.5 0.1 0.39 11.1 0.1 1.7 1 0 0 1 1 1 0 DASH complex subunit Dad2 ADIP PF11559.8 KIY65572.1 - 0.15 12.2 0.2 0.25 11.4 0.2 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding F-box-like PF12937.7 KIY65573.1 - 1.1e-06 28.4 0.2 3.8e-06 26.7 0.2 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY65573.1 - 0.00045 20.0 0.1 0.0014 18.4 0.1 1.9 1 0 0 1 1 1 1 F-box domain CorA PF01544.18 KIY65573.1 - 0.016 14.6 0.1 0.14 11.4 0.1 2.2 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF3450 PF11932.8 KIY65573.1 - 0.041 13.2 0.1 0.086 12.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) F-box-like_2 PF13013.6 KIY65573.1 - 0.053 13.5 0.3 0.25 11.3 0.1 2.3 2 1 0 2 2 2 0 F-box-like domain ADIP PF11559.8 KIY65573.1 - 0.13 12.4 0.2 0.2 11.7 0.2 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding ORF6C PF10552.9 KIY65573.1 - 0.21 11.7 0.0 0.35 10.9 0.0 1.3 1 0 0 1 1 1 0 ORF6C domain RRM_1 PF00076.22 KIY65574.1 - 4.5e-18 64.8 0.0 9.2e-08 31.8 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.11 KIY65574.1 - 0.001 19.1 0.0 0.49 10.5 0.0 2.3 2 0 0 2 2 2 2 RNA binding domain MAGE PF01454.19 KIY65575.1 - 2.3e-47 161.5 0.0 3e-47 161.1 0.0 1.2 1 0 0 1 1 1 1 MAGE family p450 PF00067.22 KIY65578.1 - 9.2e-40 136.8 0.0 1e-39 136.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Zn-C2H2_12 PF18112.1 KIY65579.1 - 0.16 12.4 0.2 0.35 11.4 0.2 1.5 1 0 0 1 1 1 0 Autophagy receptor zinc finger-C2H2 domain zf-MYND PF01753.18 KIY65580.1 - 4.7e-08 33.0 11.6 9.6e-08 32.0 11.6 1.6 1 0 0 1 1 1 1 MYND finger Peptidase_S32 PF05579.13 KIY65581.1 - 0.12 11.5 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Equine arteritis virus serine endopeptidase S32 Polysacc_deac_1 PF01522.21 KIY65582.1 - 1.7e-25 89.3 0.0 2.7e-25 88.7 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DSPc PF00782.20 KIY65583.1 - 1.3e-31 109.1 0.0 1.6e-31 108.9 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 KIY65583.1 - 0.00028 21.1 0.1 0.00041 20.6 0.1 1.2 1 0 0 1 1 1 1 Rit1 DUSP-like domain Y_phosphatase PF00102.27 KIY65583.1 - 0.009 15.6 0.0 0.012 15.2 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KIY65583.1 - 0.027 14.6 0.0 0.034 14.3 0.0 1.1 1 0 0 1 1 1 0 Inositol hexakisphosphate CDKN3 PF05706.12 KIY65583.1 - 0.027 14.1 0.0 0.035 13.8 0.0 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Glu_syn_central PF04898.14 KIY65583.1 - 0.028 13.9 0.0 0.034 13.6 0.0 1.1 1 0 0 1 1 1 0 Glutamate synthase central domain Myotub-related PF06602.14 KIY65583.1 - 0.18 10.7 0.0 0.21 10.5 0.0 1.1 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain zf-MYND PF01753.18 KIY65584.1 - 1.7e-07 31.2 12.9 3.8e-07 30.1 12.9 1.6 1 0 0 1 1 1 1 MYND finger DUF4752 PF15944.5 KIY65586.1 - 0.089 12.9 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4752) DAO PF01266.24 KIY65587.1 - 2.5e-33 116.1 5.6 6.7e-33 114.7 5.6 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 KIY65587.1 - 0.00045 20.6 0.0 0.00075 19.9 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Pyr_redox_2 PF07992.14 KIY65587.1 - 0.00069 18.9 0.0 0.00099 18.4 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIY65587.1 - 0.001 19.3 0.5 0.0029 17.8 0.5 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KIY65587.1 - 0.0035 16.5 2.4 0.0056 15.8 2.4 1.5 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 KIY65587.1 - 0.015 15.9 0.3 0.037 14.6 0.3 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.25 KIY65587.1 - 0.016 14.7 2.4 1.4 8.3 3.3 2.6 2 1 1 3 3 3 0 short chain dehydrogenase 3HCDH_N PF02737.18 KIY65587.1 - 0.017 15.0 0.1 0.025 14.5 0.1 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 KIY65587.1 - 0.018 14.6 1.1 0.029 13.9 1.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 KIY65587.1 - 0.022 14.4 0.7 0.04 13.6 0.7 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.6 KIY65587.1 - 0.026 13.8 0.4 0.038 13.2 0.4 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KIY65587.1 - 0.03 13.6 1.0 0.049 12.9 1.0 1.3 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 KIY65587.1 - 0.065 12.5 0.6 0.11 11.7 0.6 1.3 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.22 KIY65587.1 - 0.14 11.2 0.4 0.19 10.8 0.4 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A TrkA_N PF02254.18 KIY65587.1 - 0.15 12.3 0.6 0.27 11.5 0.6 1.4 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_2 PF03446.15 KIY65587.1 - 0.15 12.2 0.1 1.5 8.9 0.0 2.1 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase HI0933_like PF03486.14 KIY65587.1 - 0.25 10.0 0.7 0.36 9.5 0.7 1.2 1 0 0 1 1 1 0 HI0933-like protein Glyco_hydro_61 PF03443.14 KIY65590.1 - 1.1e-63 214.9 0.0 1.2e-63 214.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NAD_binding_10 PF13460.6 KIY65591.1 - 2.1e-22 79.9 0.0 2.4e-22 79.7 0.0 1.0 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KIY65591.1 - 0.0011 18.6 0.0 0.0025 17.4 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KIY65591.1 - 0.0039 16.7 0.0 0.0076 15.7 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KIY65591.1 - 0.018 14.2 0.0 4.3 6.4 0.0 2.1 2 0 0 2 2 2 0 Male sterility protein Sacchrp_dh_NADP PF03435.18 KIY65591.1 - 0.05 13.9 0.0 0.079 13.2 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain 3Beta_HSD PF01073.19 KIY65591.1 - 0.073 12.1 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KIY65591.1 - 0.11 11.9 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase DnaJ PF00226.31 KIY65593.1 - 2e-10 40.6 0.0 3.7e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain IDO PF01231.18 KIY65594.1 - 4.6e-132 440.9 0.0 6.6e-131 437.1 0.0 1.9 1 1 0 1 1 1 1 Indoleamine 2,3-dioxygenase Met_gamma_lyase PF06838.11 KIY65594.1 - 0.047 12.2 0.0 0.067 11.7 0.0 1.1 1 0 0 1 1 1 0 Methionine gamma-lyase SOCS_box PF07525.16 KIY65595.1 - 0.038 14.4 0.0 0.073 13.5 0.0 1.5 1 0 0 1 1 1 0 SOCS box DAO PF01266.24 KIY65596.1 - 2.9e-05 23.8 0.0 3.5e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase zf-C2H2_jaz PF12171.8 KIY65599.1 - 1.8e-19 69.5 30.9 8.9e-06 25.9 0.7 7.0 6 1 1 7 7 7 5 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KIY65599.1 - 3.4e-18 64.8 28.3 0.13 13.1 0.2 7.4 7 0 0 7 7 7 7 C2H2-type zinc finger zf-met PF12874.7 KIY65599.1 - 3.4e-12 46.3 26.6 0.0029 17.9 0.3 7.0 7 0 0 7 7 7 4 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 KIY65599.1 - 1.8e-11 43.8 30.4 0.14 12.7 0.5 7.4 7 0 0 7 7 7 5 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 KIY65599.1 - 6e-06 26.5 26.9 0.79 10.1 0.2 6.6 2 2 5 7 7 7 5 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 KIY65599.1 - 0.024 14.4 16.5 7.7 6.4 0.2 6.4 6 0 0 6 6 6 0 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 KIY65599.1 - 0.051 13.6 0.2 0.051 13.6 0.2 6.1 7 0 0 7 7 7 0 C2H2-type zinc finger Rad50_zn_hook PF04423.14 KIY65599.1 - 1.4 8.8 12.5 12 5.9 0.2 4.3 5 0 0 5 5 5 0 Rad50 zinc hook motif zf-C2HC_2 PF13913.6 KIY65599.1 - 8 6.5 17.5 22 5.1 0.0 6.0 6 1 0 6 6 6 0 zinc-finger of a C2HC-type ETRAMP PF09716.10 KIY65601.1 - 0.12 12.4 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Styelin PF17562.2 KIY65602.1 - 0.096 13.1 0.0 0.26 11.7 0.0 1.7 2 0 0 2 2 2 0 Styelin DSPc PF00782.20 KIY65603.1 - 1.9e-26 92.4 0.0 9e-22 77.3 0.0 3.3 2 1 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KIY65603.1 - 0.043 13.4 0.0 0.073 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase CAF1A PF12253.8 KIY65604.1 - 0.045 13.9 2.8 0.1 12.8 2.8 1.5 1 0 0 1 1 1 0 Chromatin assembly factor 1 subunit A Isochorismatase PF00857.20 KIY65605.1 - 9e-14 52.0 0.0 1.4e-13 51.4 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family zf-ribbon_3 PF13248.6 KIY65607.1 - 0.067 12.6 0.2 0.14 11.6 0.2 1.5 1 0 0 1 1 1 0 zinc-ribbon domain zf-C2H2_4 PF13894.6 KIY65607.1 - 0.11 13.4 1.6 0.24 12.3 1.6 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger zf-BED PF02892.15 KIY65607.1 - 0.12 12.4 1.4 0.23 11.5 1.4 1.4 1 0 0 1 1 1 0 BED zinc finger CpXC PF14353.6 KIY65607.1 - 0.16 12.0 0.3 0.31 11.1 0.3 1.3 1 0 0 1 1 1 0 CpXC protein zf-C2HE PF16278.5 KIY65607.1 - 0.88 10.1 2.7 1.7 9.2 2.7 1.4 1 0 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger Zn_clus PF00172.18 KIY65608.1 - 0.074 13.2 29.2 0.97 9.6 2.6 3.7 3 0 0 3 3 3 0 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KIY65609.1 - 1.1e-44 152.8 35.8 1.1e-44 152.8 35.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIY65609.1 - 2.6e-11 43.1 8.7 2.6e-11 43.1 8.7 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 KIY65609.1 - 2.4e-05 23.8 8.8 2.4e-05 23.8 8.8 2.1 3 1 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB MAGI_u5 PF16666.5 KIY65609.1 - 0.58 10.3 2.2 0.97 9.6 2.2 1.3 1 0 0 1 1 1 0 Unstructured region on MAGI CSN7a_helixI PF18392.1 KIY65610.1 - 0.11 12.4 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 COP9 signalosome complex subunit 7a helix I domain zf-UBP PF02148.19 KIY65611.1 - 0.18 12.2 2.5 0.33 11.3 2.5 1.4 1 0 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein Sec23_trunk PF04811.15 KIY65613.1 - 6.5e-51 173.2 0.0 1.9e-50 171.7 0.0 1.7 2 0 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 KIY65613.1 - 1.3e-23 82.8 0.3 3.7e-23 81.3 0.3 1.9 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 KIY65613.1 - 7.5e-18 65.1 0.6 1.4e-17 64.2 0.6 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 KIY65613.1 - 5.2e-15 55.2 0.9 2.2e-14 53.2 1.4 1.8 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KIY65613.1 - 2.6e-06 27.2 0.0 1.7e-05 24.6 0.0 2.2 2 0 0 2 2 2 1 Gelsolin repeat zf-FPG_IleRS PF06827.14 KIY65613.1 - 1.3 8.9 3.7 2.9 7.8 3.7 1.6 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS Fungal_trans PF04082.18 KIY65614.1 - 3.6e-20 72.1 0.0 6.3e-20 71.3 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY65614.1 - 7.1e-10 38.8 12.4 1.3e-09 38.0 12.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PQQ_3 PF13570.6 KIY65614.1 - 0.065 13.7 0.2 0.45 11.1 0.0 2.6 2 0 0 2 2 2 0 PQQ-like domain zf-RING_10 PF16685.5 KIY65614.1 - 0.28 11.4 5.6 0.57 10.4 5.6 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 SUIM_assoc PF16619.5 KIY65614.1 - 2.3 8.3 7.0 2.2 8.4 2.7 2.9 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Herpes_capsid PF06112.11 KIY65617.1 - 3.3 7.8 12.7 6 6.9 12.7 1.5 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein K1377 PF15352.6 KIY65618.1 - 3.3 5.8 14.9 8.6 4.5 14.9 1.5 1 1 0 1 1 1 0 Susceptibility to monomelic amyotrophy Mcp5_PH PF12814.7 KIY65620.1 - 3.9e-43 146.5 0.2 8.5e-43 145.4 0.2 1.6 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.29 KIY65620.1 - 0.00014 22.3 0.0 0.00035 21.1 0.0 1.7 1 0 0 1 1 1 1 PH domain CCDC144C PF14915.6 KIY65620.1 - 2.3 7.3 29.3 0.086 11.9 16.0 2.8 3 0 0 3 3 3 0 CCDC144C protein coiled-coil region KIF1B PF12423.8 KIY65620.1 - 4.7 7.7 10.2 17 5.9 0.9 4.5 4 0 0 4 4 4 0 Kinesin protein 1B MAD PF05557.13 KIY65620.1 - 6.2 5.1 28.6 0.043 12.2 20.1 1.6 2 0 0 2 2 2 0 Mitotic checkpoint protein V_ATPase_I PF01496.19 KIY65620.1 - 6.5 4.5 6.5 10 3.9 6.5 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DIOX_N PF14226.6 KIY65621.1 - 1.2e-19 71.2 0.3 1.6e-18 67.6 0.0 2.5 3 0 0 3 3 3 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KIY65621.1 - 7.6e-13 48.8 0.1 3e-12 46.9 0.0 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily RNA_pol_L_2 PF13656.6 KIY65623.1 - 9.6e-28 95.8 0.0 1.2e-27 95.5 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 KIY65623.1 - 1.2e-07 31.0 0.0 1.9e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain UPF0184 PF03670.13 KIY65623.1 - 0.095 13.1 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) Zn_clus PF00172.18 KIY65624.1 - 2e-09 37.4 5.5 3.2e-09 36.7 5.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Paralemmin PF03285.15 KIY65624.1 - 0.11 12.1 0.0 0.16 11.5 0.0 1.1 1 0 0 1 1 1 0 Paralemmin DUF2855 PF11017.8 KIY65625.1 - 3.4e-102 342.7 0.0 3.9e-102 342.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2855) Copper-fist PF00649.18 KIY65628.1 - 1.9e-22 78.5 1.1 1.9e-22 78.5 1.1 2.0 2 0 0 2 2 2 1 Copper fist DNA binding domain UbiA PF01040.18 KIY65633.1 - 1.4e-36 126.1 15.9 1.9e-36 125.7 15.9 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Lactamase_B_2 PF12706.7 KIY65634.1 - 5e-06 26.2 0.2 0.0027 17.3 0.2 2.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain DRMBL PF07522.14 KIY65634.1 - 0.0026 17.9 0.0 0.007 16.5 0.0 1.7 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B PF00753.27 KIY65634.1 - 0.0055 16.7 0.8 0.17 11.9 0.8 2.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.12 KIY65634.1 - 0.086 12.8 0.0 0.39 10.7 0.0 2.1 2 0 0 2 2 2 0 Zn-dependent metallo-hydrolase RNA specificity domain Glyco_hydro_61 PF03443.14 KIY65638.1 - 4.7e-49 167.1 0.1 5.8e-49 166.8 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Glyco_hydro_61 PF03443.14 KIY65639.1 - 1.5e-45 155.6 0.1 1.9e-45 155.3 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DinB PF05163.12 KIY65639.1 - 0.032 14.1 0.0 4.7 7.1 0.0 2.1 1 1 1 2 2 2 0 DinB family OPT PF03169.15 KIY65641.1 - 5.1e-174 580.3 49.7 5.8e-174 580.1 49.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Cyclin_C PF02984.19 KIY65641.1 - 0.13 12.3 0.1 2 8.5 0.0 2.3 2 0 0 2 2 2 0 Cyclin, C-terminal domain DUF3938 PF13074.6 KIY65641.1 - 0.6 10.4 5.6 2.4 8.5 0.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3938) CRAL_TRIO_2 PF13716.6 KIY65642.1 - 8.9e-30 103.7 0.1 1.7e-29 102.7 0.1 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain RhoGAP PF00620.27 KIY65642.1 - 2.1e-28 99.1 0.0 3.8e-28 98.2 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain CRAL_TRIO PF00650.20 KIY65642.1 - 1.9e-05 24.5 0.1 8.3e-05 22.4 0.1 1.9 1 1 0 1 1 1 1 CRAL/TRIO domain Peptidase_C62 PF12380.8 KIY65643.1 - 0.074 12.2 0.0 0.1 11.7 0.0 1.1 1 0 0 1 1 1 0 Gill-associated viral 3C-like peptidase UbiA PF01040.18 KIY65644.1 - 1.8e-36 125.7 14.6 2.3e-36 125.4 14.6 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family MLTR_LBD PF17765.1 KIY65645.1 - 0.2 11.8 0.0 0.26 11.4 0.0 1.1 1 0 0 1 1 1 0 MmyB-like transcription regulator ligand binding domain Far-17a_AIG1 PF04750.14 KIY65646.1 - 2.5e-19 69.4 1.6 3.8e-19 68.8 1.6 1.2 1 1 0 1 1 1 1 FAR-17a/AIG1-like protein Far-17a_AIG1 PF04750.14 KIY65647.1 - 1.1e-28 99.9 2.4 1.3e-28 99.7 2.4 1.1 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein zf-C2H2_jaz PF12171.8 KIY65648.1 - 9.7e-05 22.5 0.1 0.0002 21.5 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 KIY65648.1 - 0.0048 17.3 1.1 0.0048 17.3 1.1 2.9 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIY65648.1 - 0.011 16.5 0.4 0.011 16.5 0.4 2.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 KIY65648.1 - 0.25 10.8 4.4 6.5 6.3 0.6 2.8 2 1 0 2 2 2 0 zinc-ribbon domain APH PF01636.23 KIY65649.1 - 1.1e-13 51.6 0.0 4.1e-13 49.8 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 KIY65649.1 - 7.7e-06 25.0 0.0 0.0056 15.6 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) EcKinase PF02958.20 KIY65649.1 - 0.0008 18.8 0.0 0.0015 17.9 0.0 1.4 1 0 0 1 1 1 1 Ecdysteroid kinase Kdo PF06293.14 KIY65649.1 - 0.068 12.5 0.0 11 5.4 0.0 2.3 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family UbiA PF01040.18 KIY65650.1 - 9.5e-37 126.7 14.9 1.2e-36 126.3 14.9 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family YceG_bac PF14266.6 KIY65651.1 - 0.19 10.6 0.0 0.27 10.1 0.0 1.1 1 0 0 1 1 1 0 Putative component of 'biosynthetic module' F-box-like PF12937.7 KIY65653.1 - 1.2e-06 28.3 2.2 3.9e-06 26.7 2.2 1.9 1 1 0 1 1 1 1 F-box-like DUF4164 PF13747.6 KIY65653.1 - 0.0011 19.2 0.3 0.0025 18.1 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4164) F-box-like PF12937.7 KIY65654.1 - 3.8e-06 26.7 0.5 1.3e-05 25.0 0.5 2.0 1 1 0 1 1 1 1 F-box-like LRR_8 PF13855.6 KIY65654.1 - 0.36 10.6 2.9 0.38 10.6 0.1 2.6 3 0 0 3 3 3 0 Leucine rich repeat F-box-like PF12937.7 KIY65655.1 - 2.7e-06 27.1 1.9 8.4e-06 25.6 1.9 1.9 1 1 0 1 1 1 1 F-box-like F-box-like PF12937.7 KIY65658.1 - 4e-07 29.8 2.5 2e-06 27.6 2.5 2.1 1 1 0 1 1 1 1 F-box-like DUF2730 PF10805.8 KIY65658.1 - 0.074 13.1 0.3 0.15 12.2 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) DUF4502 PF14950.6 KIY65661.1 - 0.059 12.8 0.2 0.079 12.4 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4502) Ribosomal_S7 PF00177.21 KIY65662.1 - 0.06 13.0 0.0 0.065 12.9 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein S7p/S5e TPR_10 PF13374.6 KIY65662.1 - 0.18 11.7 0.6 0.27 11.2 0.6 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat Sugar_tr PF00083.24 KIY65663.1 - 8.3e-121 404.0 12.3 9.5e-121 403.8 12.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY65663.1 - 2.8e-16 59.4 29.9 2.5e-13 49.7 12.1 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily BAR PF03114.18 KIY65664.1 - 7.8e-40 137.0 9.2 1e-39 136.6 9.2 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 KIY65664.1 - 2.3e-13 49.5 0.8 3.7e-13 48.9 0.1 1.8 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KIY65664.1 - 1.7e-12 47.0 0.1 3e-12 46.2 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KIY65664.1 - 1.1e-08 34.6 0.0 2.1e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain BAR_3 PF16746.5 KIY65664.1 - 0.00046 20.0 2.9 0.0011 18.8 2.9 1.5 1 0 0 1 1 1 1 BAR domain of APPL family FbpA PF05833.11 KIY65664.1 - 0.0079 15.0 3.6 0.014 14.2 3.6 1.3 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) Cas_Cas1 PF01867.16 KIY65664.1 - 0.014 14.6 0.4 0.021 14.0 0.4 1.3 1 0 0 1 1 1 0 CRISPR associated protein Cas1 MscS_TM PF12794.7 KIY65664.1 - 2 7.2 2.9 3.1 6.6 2.9 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 AAA_23 PF13476.6 KIY65664.1 - 4.7 7.7 7.4 6.5 7.2 6.2 1.9 1 1 0 1 1 1 0 AAA domain SWIB PF02201.18 KIY65666.1 - 9e-23 80.0 0.0 1.9e-22 78.9 0.0 1.6 1 0 0 1 1 1 1 SWIB/MDM2 domain Pkinase PF00069.25 KIY65667.1 - 1.1e-36 126.5 0.0 3.3e-35 121.7 0.0 2.5 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY65667.1 - 3.1e-19 69.3 0.0 5.5e-19 68.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HSP90 PF00183.18 KIY65668.1 - 8.9e-222 737.6 26.8 1e-221 737.3 26.8 1.0 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 KIY65668.1 - 2.6e-13 50.4 0.0 4.9e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KIY65668.1 - 1.4e-10 41.1 0.1 4.2e-10 39.6 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Cofac_haem_bdg PF04187.13 KIY65668.1 - 0.16 11.9 0.0 0.43 10.5 0.0 1.8 1 0 0 1 1 1 0 Haem-binding uptake, Tiki superfamily, ChaN U3_assoc_6 PF08640.11 KIY65669.1 - 1.7e-29 101.7 3.3 1.3e-27 95.7 2.8 2.6 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 NRDE-2 PF08424.10 KIY65669.1 - 0.00038 19.7 0.0 0.071 12.2 0.0 3.2 2 1 1 3 3 3 2 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 KIY65669.1 - 0.022 15.5 9.4 2.2 9.4 0.0 6.4 5 2 3 8 8 8 0 Tetratricopeptide repeat Arg_decarbox_C PF17944.1 KIY65669.1 - 0.098 13.2 0.9 0.42 11.2 0.3 2.5 2 0 0 2 2 2 0 Arginine decarboxylase C-terminal helical extension CDT1_C PF16679.5 KIY65669.1 - 0.15 12.5 0.1 0.15 12.5 0.1 2.4 2 0 0 2 2 2 0 DNA replication factor Cdt1 C-terminal domain Ribosomal_S21 PF01165.20 KIY65669.1 - 0.31 10.8 2.4 11 5.9 0.6 3.0 2 0 0 2 2 2 0 Ribosomal protein S21 Forkhead PF00250.18 KIY65671.1 - 4.1e-12 46.2 0.0 6.8e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain CHCH PF06747.13 KIY65672.1 - 1.9e-08 34.2 3.1 2.8e-08 33.7 3.1 1.3 1 0 0 1 1 1 1 CHCH domain GCK PF07802.11 KIY65672.1 - 0.00011 22.6 0.7 0.00012 22.4 0.7 1.1 1 0 0 1 1 1 1 GCK domain DUF4472 PF14739.6 KIY65674.1 - 3.4e-06 27.8 3.1 0.059 14.1 0.1 2.6 2 1 0 2 2 2 2 Domain of unknown function (DUF4472) DUF4640 PF15480.6 KIY65674.1 - 0.0086 15.9 11.6 0.37 10.5 6.8 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4640) Macoilin PF09726.9 KIY65674.1 - 0.025 13.2 19.7 0.036 12.6 19.7 1.2 1 0 0 1 1 1 0 Macoilin family CLZ PF16526.5 KIY65674.1 - 0.028 14.8 3.7 3.9 7.9 0.2 3.4 2 2 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4893 PF16233.5 KIY65674.1 - 0.036 13.7 2.2 0.56 9.8 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4893) Lectin_N PF03954.14 KIY65674.1 - 0.083 12.6 4.3 2.4 7.9 0.3 2.5 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain Apt1 PF10351.9 KIY65674.1 - 0.1 11.5 14.5 0.11 11.3 13.5 1.5 1 1 0 1 1 1 0 Golgi-body localisation protein domain MoCF_biosynth PF00994.24 KIY65674.1 - 0.15 11.7 3.4 5.4 6.7 0.3 2.5 2 0 0 2 2 2 0 Probable molybdopterin binding domain BST2 PF16716.5 KIY65674.1 - 0.28 11.8 4.0 15 6.3 0.3 2.8 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 HisK_N PF09385.10 KIY65674.1 - 0.33 10.9 2.0 12 5.9 0.1 2.6 3 0 0 3 3 3 0 Histidine kinase N terminal Med9 PF07544.13 KIY65674.1 - 0.53 10.4 3.5 16 5.7 0.3 2.5 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 PI3K_1B_p101 PF10486.9 KIY65674.1 - 4.1 5.1 8.9 5.7 4.6 8.9 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit PAP1 PF08601.10 KIY65674.1 - 5.6 6.6 26.3 0.15 11.8 19.9 1.6 2 0 0 2 2 2 0 Transcription factor PAP1 ALS_ss_C PF10369.9 KIY65676.1 - 1.6e-18 66.6 0.1 5.9e-17 61.6 0.0 2.3 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.25 KIY65676.1 - 3.9e-13 48.9 0.0 8.2e-13 47.9 0.0 1.6 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.6 KIY65676.1 - 1.9e-06 27.6 0.0 3.6e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 ACT domain COG5 PF10392.9 KIY65678.1 - 1.1e-25 90.3 2.4 3.4e-25 88.8 1.1 2.5 3 0 0 3 3 3 1 Golgi transport complex subunit 5 Vps51 PF08700.11 KIY65678.1 - 0.00019 21.4 0.1 0.0013 18.8 0.1 2.5 1 1 0 1 1 1 1 Vps51/Vps67 COG2 PF06148.11 KIY65678.1 - 0.088 12.9 2.7 0.2 11.7 0.8 2.6 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 NPV_P10 PF05531.12 KIY65678.1 - 0.097 13.2 4.2 18 5.9 0.1 3.5 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein NifW PF03206.14 KIY65678.1 - 0.13 12.8 0.3 2.5 8.7 0.0 3.0 3 0 0 3 3 3 0 Nitrogen fixation protein NifW Sec5 PF15469.6 KIY65678.1 - 0.18 11.6 0.5 1.3 8.8 0.1 2.3 2 0 0 2 2 2 0 Exocyst complex component Sec5 Dor1 PF04124.12 KIY65678.1 - 0.34 9.5 4.5 1.1 7.8 0.8 2.3 2 0 0 2 2 2 0 Dor1-like family Zw10 PF06248.13 KIY65678.1 - 0.45 9.0 3.3 0.31 9.6 1.0 1.9 2 1 0 2 2 2 0 Centromere/kinetochore Zw10 Mod_r PF07200.13 KIY65678.1 - 0.57 10.3 3.4 1 9.5 0.2 2.7 3 0 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Baculo_PEP_C PF04513.12 KIY65678.1 - 0.65 10.0 11.8 4.3 7.4 0.9 4.6 3 2 2 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus PE PF00934.20 KIY65678.1 - 4.7 7.6 11.4 3 8.2 0.1 4.2 5 1 1 6 6 6 0 PE family DUF3759 PF12585.8 KIY65679.1 - 0.077 13.0 0.0 0.22 11.6 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3759) LRR_4 PF12799.7 KIY65680.1 - 0.21 12.1 0.4 5 7.7 0.0 3.2 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) DUF2461 PF09365.10 KIY65681.1 - 1e-78 264.0 0.0 1e-78 264.0 0.0 1.6 2 0 0 2 2 2 1 Conserved hypothetical protein (DUF2461) DTHCT PF08070.11 KIY65681.1 - 0.0001 23.0 10.4 0.00023 21.8 10.4 1.6 1 0 0 1 1 1 1 DTHCT (NUC029) region NARP1 PF12569.8 KIY65681.1 - 6.7 5.5 8.4 9.3 5.0 8.4 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Ribosomal_L11_N PF03946.14 KIY65682.1 - 8e-24 83.3 0.1 1.2e-23 82.7 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 KIY65682.1 - 2.7e-17 63.1 0.3 4.6e-17 62.3 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Cyclin PF08613.11 KIY65683.1 - 3.9e-29 102.1 0.1 5.7e-29 101.5 0.1 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 KIY65683.1 - 1.8e-05 24.5 1.5 5.8e-05 22.8 1.3 1.8 1 1 1 2 2 2 1 Cyclin, N-terminal domain UCH PF00443.29 KIY65684.1 - 1.2e-24 87.3 0.0 1.6e-24 86.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KIY65684.1 - 3.4e-11 43.3 0.2 6.4e-11 42.4 0.2 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein HECT_2 PF09814.9 KIY65685.1 - 1.9e-52 178.4 0.0 2.7e-52 177.9 0.0 1.2 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding DUF3421 PF11901.8 KIY65687.1 - 6e-24 84.3 0.0 7e-20 71.1 0.0 1.9 1 1 1 2 2 2 2 Protein of unknown function (DUF3421) Polysacc_deac_1 PF01522.21 KIY65688.1 - 1.5e-16 60.4 0.0 2.8e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Pkinase PF00069.25 KIY65689.1 - 2.3e-25 89.5 0.0 3.7e-24 85.5 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY65689.1 - 3e-12 46.4 0.1 3.9e-09 36.2 0.0 2.8 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KIY65689.1 - 4.8e-08 32.7 0.0 6e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KIY65689.1 - 0.0035 17.3 1.4 0.0053 16.7 0.5 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KIY65689.1 - 0.022 14.1 0.1 0.038 13.3 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4679 PF15728.5 KIY65689.1 - 1.9 7.4 27.2 1.5 7.8 25.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4679) Sec62 PF03839.16 KIY65690.1 - 4.1e-35 121.3 0.8 5.9e-35 120.7 0.8 1.4 1 1 0 1 1 1 1 Translocation protein Sec62 Polysacc_deac_1 PF01522.21 KIY65692.1 - 3.4e-24 85.1 0.0 8.6e-24 83.8 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide deacetylase MFS_1 PF07690.16 KIY65693.1 - 1.5e-22 80.0 83.4 6.8e-21 74.6 48.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily F-box-like PF12937.7 KIY65694.1 - 1.4e-06 28.0 3.1 4.4e-06 26.5 3.1 1.8 1 1 0 1 1 1 1 F-box-like F-box-like_2 PF13013.6 KIY65694.1 - 0.0039 17.1 0.2 0.0048 16.9 0.2 1.4 1 1 0 1 1 1 1 F-box-like domain APG6_N PF17675.1 KIY65694.1 - 0.04 14.5 0.0 0.063 13.8 0.0 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region TMF_TATA_bd PF12325.8 KIY65694.1 - 0.082 13.1 0.1 0.13 12.5 0.1 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding TPD52 PF04201.15 KIY65694.1 - 0.095 12.3 0.1 0.15 11.6 0.1 1.2 1 0 0 1 1 1 0 Tumour protein D52 family Pectate_lyase PF03211.13 KIY65696.1 - 1e-75 253.8 5.9 1.1e-75 253.6 5.9 1.0 1 0 0 1 1 1 1 Pectate lyase dsrm PF00035.26 KIY65697.1 - 3.3e-06 27.7 0.0 3.9e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Double-stranded RNA binding motif zf-XS PF03470.14 KIY65697.1 - 0.043 14.1 0.1 0.061 13.6 0.1 1.2 1 0 0 1 1 1 0 XS zinc finger domain DUF3104 PF11302.8 KIY65697.1 - 0.093 12.5 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3104) RhoGEF PF00621.20 KIY65698.1 - 5.4e-64 215.8 0.9 1.8e-32 113.0 0.1 2.3 2 0 0 2 2 2 2 RhoGEF domain CNH PF00780.22 KIY65698.1 - 4.6e-58 197.0 0.0 7.3e-58 196.3 0.0 1.2 1 0 0 1 1 1 1 CNH domain PH_5 PF15405.6 KIY65698.1 - 2.7e-13 50.2 0.0 6.1e-13 49.0 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain DEP PF00610.21 KIY65698.1 - 0.00024 21.1 0.0 0.00062 19.8 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH PF00169.29 KIY65698.1 - 0.048 14.2 0.0 1.3 9.6 0.0 2.9 2 1 0 2 2 2 0 PH domain Acetyltransf_3 PF13302.7 KIY65699.1 - 3.8e-19 69.7 0.1 4.9e-19 69.4 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIY65699.1 - 2.4e-12 47.1 0.0 3.3e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 KIY65699.1 - 6.7e-09 36.1 0.0 9.4e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KIY65699.1 - 1.5e-07 31.4 0.0 2.6e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KIY65699.1 - 3.5e-07 30.5 0.0 5e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIY65699.1 - 1.2e-06 28.4 0.0 2.1e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 KIY65699.1 - 2.4e-05 24.0 0.0 9.3e-05 22.1 0.0 1.7 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain CDC45 PF02724.14 KIY65700.1 - 0.077 11.3 23.5 0.12 10.6 23.5 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF2828 PF11443.8 KIY65700.1 - 0.14 10.2 13.6 0.22 9.6 13.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) LMBR1 PF04791.16 KIY65700.1 - 0.21 10.5 2.4 0.2 10.5 2.4 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein FAM60A PF15396.6 KIY65700.1 - 1.6 8.7 22.9 1 9.3 18.6 2.0 2 0 0 2 2 2 0 Protein Family FAM60A DUF262 PF03235.14 KIY65700.1 - 5.2 7.2 10.7 12 6.0 10.7 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF262 UBX PF00789.20 KIY65701.1 - 2.9e-11 43.4 0.5 6.9e-11 42.2 0.1 1.9 2 0 0 2 2 2 1 UBX domain UBA PF00627.31 KIY65701.1 - 2.1e-05 24.3 0.1 7.9e-05 22.5 0.0 2.1 2 0 0 2 2 2 1 UBA/TS-N domain ROS_MUCR PF05443.11 KIY65701.1 - 0.11 12.5 0.2 0.11 12.5 0.2 2.5 1 1 0 2 2 2 0 ROS/MUCR transcriptional regulator protein zinc_ribbon_4 PF13717.6 KIY65701.1 - 0.15 12.0 0.1 0.31 11.0 0.1 1.6 1 0 0 1 1 1 0 zinc-ribbon domain zf-C2H2_2 PF12756.7 KIY65701.1 - 0.15 12.4 1.3 0.25 11.7 0.4 1.8 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Hamartin PF04388.12 KIY65701.1 - 3.2 6.3 13.0 3.7 6.1 13.0 1.1 1 0 0 1 1 1 0 Hamartin protein F-box-like PF12937.7 KIY65702.1 - 4.1e-08 33.0 0.5 1.6e-07 31.1 0.5 2.1 1 0 0 1 1 1 1 F-box-like LisH PF08513.11 KIY65703.1 - 4.3e-07 29.7 0.1 6.7e-07 29.0 0.1 1.3 1 0 0 1 1 1 1 LisH Lipase_GDSL PF00657.22 KIY65704.1 - 4.5e-10 39.8 0.0 9.2e-10 38.8 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 KIY65704.1 - 0.00016 22.1 0.1 0.00061 20.2 0.1 1.9 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family F-box-like PF12937.7 KIY65705.1 - 0.0005 19.9 0.3 0.001 18.9 0.3 1.6 1 0 0 1 1 1 1 F-box-like AAA PF00004.29 KIY65706.1 - 1.2e-43 148.7 0.0 2.8e-14 53.7 0.0 5.9 5 0 0 5 5 5 4 ATPase family associated with various cellular activities (AAA) AAA_12 PF13087.6 KIY65706.1 - 3e-39 134.7 0.0 6.3e-39 133.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KIY65706.1 - 2.7e-24 86.4 33.5 5.4e-21 75.6 0.0 6.5 6 0 0 6 6 5 3 AAA domain AAA_19 PF13245.6 KIY65706.1 - 1e-19 71.3 0.1 6.7e-08 33.0 0.0 5.7 6 1 0 6 6 4 3 AAA domain AAA_30 PF13604.6 KIY65706.1 - 1.9e-16 60.3 14.1 0.00058 19.6 0.0 6.6 6 0 0 6 6 5 5 AAA domain AAA_lid_6 PF17866.1 KIY65706.1 - 8.4e-16 57.9 5.4 1e-06 28.8 0.2 4.6 4 0 0 4 4 3 2 AAA lid domain AAA_5 PF07728.14 KIY65706.1 - 3.8e-13 49.6 0.1 0.015 15.3 0.0 4.8 4 0 0 4 4 4 3 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KIY65706.1 - 1.4e-09 37.9 0.7 0.014 15.2 0.0 5.0 5 0 0 5 5 4 2 Holliday junction DNA helicase RuvB P-loop domain Viral_helicase1 PF01443.18 KIY65706.1 - 4.2e-09 36.5 0.3 0.36 10.5 0.0 5.7 6 0 0 6 6 6 2 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.22 KIY65706.1 - 1.6e-08 34.8 0.1 0.91 9.9 0.0 4.8 4 0 0 4 4 4 1 RNA helicase Mg_chelatase PF01078.21 KIY65706.1 - 1.9e-08 33.9 0.8 0.61 9.4 0.0 4.4 4 0 0 4 4 4 3 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 KIY65706.1 - 2e-08 34.6 13.8 0.23 11.8 0.0 8.3 7 2 1 8 8 7 2 AAA domain AAA_16 PF13191.6 KIY65706.1 - 2.5e-06 28.0 12.3 0.0082 16.5 0.1 6.0 5 0 0 5 5 4 1 AAA ATPase domain IstB_IS21 PF01695.17 KIY65706.1 - 2.9e-06 27.1 0.1 3.2 7.5 0.0 4.5 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_24 PF13479.6 KIY65706.1 - 6.7e-06 26.0 9.3 2 8.1 0.0 5.8 5 1 0 5 5 5 2 AAA domain DUF2075 PF09848.9 KIY65706.1 - 8.1e-06 25.3 5.2 0.12 11.6 0.0 6.3 5 2 0 5 5 5 1 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 KIY65706.1 - 3.5e-05 23.3 2.5 1.5 8.2 0.0 4.6 5 0 0 5 5 4 2 PhoH-like protein Torsin PF06309.11 KIY65706.1 - 4.1e-05 23.7 0.1 7.4 6.7 0.0 4.4 4 0 0 4 4 4 0 Torsin AAA_33 PF13671.6 KIY65706.1 - 6.2e-05 23.2 16.5 0.22 11.7 0.1 5.6 5 1 0 5 5 4 2 AAA domain Sigma54_activat PF00158.26 KIY65706.1 - 0.00046 19.9 0.3 4.1 7.1 0.0 4.7 4 1 0 4 4 4 1 Sigma-54 interaction domain TsaE PF02367.17 KIY65706.1 - 0.0012 18.8 1.9 3 7.9 0.1 3.9 4 0 0 4 4 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 KIY65706.1 - 0.0019 18.2 0.2 6.3 6.7 0.0 4.2 4 0 0 4 4 4 0 RsgA GTPase AAA_7 PF12775.7 KIY65706.1 - 0.0025 17.3 4.9 0.62 9.6 0.0 4.2 4 0 0 4 4 4 1 P-loop containing dynein motor region 6PF2K PF01591.18 KIY65706.1 - 0.0032 16.8 0.2 0.047 13.0 0.0 3.0 3 0 0 3 3 3 1 6-phosphofructo-2-kinase NTPase_1 PF03266.15 KIY65706.1 - 0.004 17.1 2.6 9.6 6.1 0.0 4.6 5 0 0 5 5 4 0 NTPase SRP54 PF00448.22 KIY65706.1 - 0.0042 16.7 3.6 1.4 8.5 0.0 4.4 5 0 0 5 5 5 1 SRP54-type protein, GTPase domain KTI12 PF08433.10 KIY65706.1 - 0.0043 16.5 0.1 3 7.2 0.0 3.6 3 0 0 3 3 3 1 Chromatin associated protein KTI12 DEAD PF00270.29 KIY65706.1 - 0.0047 16.7 0.3 0.91 9.3 0.0 4.0 4 0 0 4 4 4 1 DEAD/DEAH box helicase AAA_18 PF13238.6 KIY65706.1 - 0.0048 17.4 17.1 2.7 8.5 0.0 6.2 6 0 0 6 6 4 1 AAA domain ResIII PF04851.15 KIY65706.1 - 0.0051 16.8 11.0 0.016 15.2 0.0 5.1 6 0 0 6 6 4 1 Type III restriction enzyme, res subunit ATPase PF06745.13 KIY65706.1 - 0.01 15.2 3.9 7.2 5.9 0.0 4.4 5 0 0 5 5 4 0 KaiC AAA_25 PF13481.6 KIY65706.1 - 0.027 14.1 8.6 2.9 7.4 0.0 5.5 6 0 0 6 6 5 0 AAA domain Helicase_RecD PF05127.14 KIY65706.1 - 0.057 13.3 0.0 2.2 8.1 0.0 3.5 4 0 0 4 4 3 0 Helicase CbiA PF01656.23 KIY65706.1 - 0.17 11.9 3.2 9.9 6.2 0.0 4.2 4 0 0 4 4 4 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_28 PF13521.6 KIY65706.1 - 0.44 10.8 22.8 0.97 9.7 0.0 5.5 6 0 0 6 6 4 0 AAA domain NACHT PF05729.12 KIY65706.1 - 0.81 9.6 6.9 24 4.8 0.0 4.2 4 0 0 4 4 4 0 NACHT domain ADK PF00406.22 KIY65706.1 - 6.7 6.8 8.1 24 5.0 0.0 4.1 4 0 0 4 4 3 0 Adenylate kinase Mt_ATP-synt_B PF05405.14 KIY65707.1 - 3.3e-42 143.9 7.7 4e-42 143.6 7.7 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) ComK PF06338.11 KIY65707.1 - 0.0093 15.6 0.9 0.2 11.3 0.3 2.2 1 1 1 2 2 2 1 ComK protein DUF5623 PF18536.1 KIY65707.1 - 0.011 16.0 1.8 0.024 14.9 0.7 1.9 1 1 0 2 2 2 0 Domain of unknown function (DUF5623) PE PF00934.20 KIY65707.1 - 0.044 14.1 1.4 0.044 14.1 1.4 1.9 3 0 0 3 3 3 0 PE family Fib_alpha PF08702.10 KIY65707.1 - 0.11 12.7 5.5 0.16 12.1 5.5 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Peptidase_C10 PF01640.17 KIY65707.1 - 0.16 12.3 0.9 0.19 12.0 0.9 1.2 1 0 0 1 1 1 0 Peptidase C10 family DUF2175 PF09943.9 KIY65707.1 - 0.45 10.8 4.7 0.57 10.5 1.4 2.5 1 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) RTA1 PF04479.13 KIY65708.1 - 5.2e-40 137.3 3.5 7.6e-40 136.7 3.5 1.2 1 0 0 1 1 1 1 RTA1 like protein DUF4386 PF14329.6 KIY65708.1 - 0.00078 19.4 0.3 0.00078 19.4 0.3 1.7 2 1 0 2 2 2 1 Domain of unknown function (DUF4386) TraP PF07296.11 KIY65708.1 - 0.1 11.8 1.0 0.2 10.8 0.1 1.9 1 1 1 2 2 2 0 TraP protein N-glycanase_N PF09112.10 KIY65708.1 - 0.24 11.2 1.1 2.4 7.9 0.2 2.2 1 1 1 2 2 2 0 Peptide-N-glycosidase F, N terminal KASH PF10541.9 KIY65708.1 - 1.2 9.4 5.2 4.7 7.6 2.4 2.3 2 0 0 2 2 2 0 Nuclear envelope localisation domain HSF_DNA-bind PF00447.17 KIY65710.1 - 1.3e-28 99.5 0.5 2.1e-28 98.8 0.5 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding DUF4606 PF15379.6 KIY65710.1 - 0.033 14.4 0.1 0.063 13.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4606) Totivirus_coat PF05518.11 KIY65710.1 - 0.093 10.8 3.6 0.12 10.5 3.6 1.0 1 0 0 1 1 1 0 Totivirus coat protein Thaumatin PF00314.17 KIY65712.1 - 1.7e-11 44.2 6.4 3.3e-11 43.2 6.4 1.5 1 1 0 1 1 1 1 Thaumatin family Pkinase PF00069.25 KIY65713.1 - 2.8e-50 171.1 0.2 3.4e-50 170.8 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY65713.1 - 8.4e-27 94.1 0.1 1.1e-26 93.7 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY65713.1 - 2.3e-05 23.8 0.0 4.4e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KIY65713.1 - 0.00097 18.5 0.8 0.0015 17.9 0.8 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIY65713.1 - 0.0077 16.2 0.1 0.25 11.3 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KIY65713.1 - 0.0099 14.7 0.0 0.015 14.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 KIY65713.1 - 0.015 14.9 0.2 0.036 13.7 0.0 1.7 2 0 0 2 2 2 0 RIO1 family PRP38 PF03371.15 KIY65714.1 - 6.1e-59 198.8 0.2 7.4e-59 198.5 0.2 1.1 1 0 0 1 1 1 1 PRP38 family DUF1645 PF07816.11 KIY65714.1 - 0.0037 17.9 11.8 0.0057 17.3 11.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1645) PRP38_assoc PF12871.7 KIY65714.1 - 0.036 14.7 32.8 0.065 13.8 32.8 1.4 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term DUF2457 PF10446.9 KIY65714.1 - 2 7.5 16.8 2.4 7.2 16.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RSRP PF17069.5 KIY65714.1 - 2.4 7.6 41.1 3.5 7.1 41.1 1.2 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 Ribosomal_L27A PF00828.19 KIY65715.1 - 1e-32 113.5 0.0 1.4e-32 113.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Pkinase PF00069.25 KIY65716.1 - 1.7e-69 234.1 0.0 2.2e-69 233.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY65716.1 - 1.3e-42 145.9 0.0 1.7e-42 145.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY65716.1 - 4.5e-07 29.5 0.0 2.9e-06 26.8 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KIY65716.1 - 0.00086 18.7 0.1 0.0016 17.8 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIY65716.1 - 0.0032 17.4 0.8 0.31 10.9 0.0 2.7 2 1 1 3 3 3 1 Phosphotransferase enzyme family FTA2 PF13095.6 KIY65716.1 - 0.0073 16.0 0.2 0.02 14.5 0.1 1.8 1 1 1 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 YrbL-PhoP_reg PF10707.9 KIY65716.1 - 0.023 14.2 0.0 0.046 13.2 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.22 KIY65716.1 - 0.033 13.8 0.0 0.062 12.9 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 KIY65716.1 - 0.089 11.6 0.2 0.17 10.6 0.0 1.4 2 0 0 2 2 2 0 Fungal protein kinase Radical_SAM_C PF16199.5 KIY65716.1 - 0.13 12.3 0.1 0.53 10.3 0.0 2.0 2 0 0 2 2 2 0 Radical_SAM C-terminal domain Seadorna_VP7 PF07387.11 KIY65716.1 - 0.14 11.1 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 F-box-like PF12937.7 KIY65718.1 - 3.4e-10 39.6 1.4 9.2e-10 38.3 1.4 1.8 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.6 KIY65718.1 - 0.14 12.2 0.4 0.79 9.7 0.4 2.2 1 1 0 1 1 1 0 F-box-like domain PALP PF00291.25 KIY65719.1 - 1.4e-59 202.0 1.2 1.8e-59 201.6 1.2 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Type_III_YscG PF09477.10 KIY65720.1 - 0.79 9.8 9.8 8.6 6.5 0.1 4.9 4 1 2 6 6 6 0 Bacterial type II secretion system chaperone protein (type_III_yscG) CLP1_P PF16575.5 KIY65721.1 - 2.9e-34 118.5 0.0 5.1e-34 117.7 0.0 1.4 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_14 PF13173.6 KIY65721.1 - 0.001 19.1 0.0 0.0024 17.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KIY65721.1 - 0.0091 15.9 0.0 0.014 15.3 0.0 1.2 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 KIY65721.1 - 0.16 12.4 0.1 0.44 11.0 0.0 1.7 2 0 0 2 2 2 0 RNA helicase FtsK_SpoIIIE PF01580.18 KIY65721.1 - 0.18 11.2 0.0 0.29 10.4 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family ADH_N PF08240.12 KIY65723.1 - 3.2e-27 94.6 2.1 3.7e-27 94.3 0.7 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KIY65723.1 - 8.8e-21 74.2 0.2 2.2e-20 73.0 0.2 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KIY65723.1 - 8.7e-07 30.1 0.0 1.6e-06 29.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KIY65723.1 - 1.2e-05 24.8 0.6 2.5e-05 23.7 0.6 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Glu_dehyd_C PF16912.5 KIY65723.1 - 2.6e-05 23.8 1.9 9e-05 22.1 1.9 1.9 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus TrkA_N PF02254.18 KIY65723.1 - 0.00034 20.8 0.2 0.00079 19.7 0.2 1.6 1 0 0 1 1 1 1 TrkA-N domain Pyr_redox_3 PF13738.6 KIY65723.1 - 0.12 11.6 0.1 0.2 10.9 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase IPPT PF01715.17 KIY65725.1 - 7.5e-59 199.3 0.4 2.3e-58 197.7 0.4 1.7 1 1 0 1 1 1 1 IPP transferase IPT PF01745.16 KIY65725.1 - 0.00039 19.9 0.0 0.0011 18.5 0.0 1.7 1 0 0 1 1 1 1 Isopentenyl transferase Sigma54_CBD PF04963.13 KIY65725.1 - 0.055 13.3 0.0 0.097 12.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 factor, core binding domain AAA PF00004.29 KIY65725.1 - 0.095 13.1 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.17 KIY65725.1 - 0.14 12.2 1.3 0.48 10.5 0.1 2.4 2 1 1 3 3 3 0 Helicase HerA, central domain AAA_18 PF13238.6 KIY65725.1 - 0.28 11.7 2.5 0.35 11.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KIY65725.1 - 1.2 9.3 5.5 0.25 11.5 0.3 2.5 2 1 0 2 2 2 0 AAA domain DHDPS PF00701.22 KIY65726.1 - 4.6e-28 97.8 0.0 5.3e-28 97.5 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family CbiD PF01888.17 KIY65726.1 - 0.099 11.9 0.7 0.28 10.4 0.1 1.8 2 0 0 2 2 2 0 CbiD tRNA-synt_2 PF00152.20 KIY65726.1 - 0.23 10.5 0.0 0.37 9.8 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class II (D, K and N) Ank_5 PF13857.6 KIY65728.1 - 8e-13 48.3 0.1 2.1e-05 24.7 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KIY65728.1 - 4.1e-12 46.4 0.0 1e-07 32.4 0.0 3.1 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KIY65728.1 - 1e-10 42.1 0.0 1.6e-10 41.4 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KIY65728.1 - 4.8e-10 38.8 0.2 0.00012 22.2 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 KIY65728.1 - 6.9e-09 35.8 0.7 0.0016 18.8 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeat Pkinase PF00069.25 KIY65729.1 - 2.6e-41 141.7 0.0 7.4e-41 140.2 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY65729.1 - 6.2e-18 65.0 0.0 1e-17 64.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KIY65729.1 - 0.01 15.2 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIY65729.1 - 0.048 13.6 0.0 0.13 12.2 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KIY65729.1 - 0.06 12.7 0.0 0.096 12.0 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 KIY65729.1 - 0.23 10.2 0.0 0.33 9.7 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 KIY65729.1 - 0.24 10.3 0.0 0.35 9.8 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain PHD PF00628.29 KIY65730.1 - 1.1e-15 57.2 19.9 2.4e-08 33.7 9.4 3.2 3 0 0 3 3 3 2 PHD-finger PHD_2 PF13831.6 KIY65730.1 - 0.0018 17.8 15.0 0.1 12.2 0.8 3.3 3 0 0 3 3 3 2 PHD-finger zf-PHD-like PF15446.6 KIY65730.1 - 0.0024 17.5 4.0 0.13 11.9 2.9 2.8 2 0 0 2 2 2 1 PHD/FYVE-zinc-finger like domain zf-RING-like PF08746.11 KIY65730.1 - 0.89 9.9 12.9 4.4 7.7 0.2 2.4 2 0 0 2 2 2 0 RING-like domain Aminotran_1_2 PF00155.21 KIY65731.1 - 1.4e-38 133.1 0.0 1.6e-38 132.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KIY65731.1 - 0.17 10.4 0.0 0.26 9.8 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme BCDHK_Adom3 PF10436.9 KIY65732.1 - 9.5e-36 123.1 0.0 1.3e-35 122.7 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KIY65732.1 - 6.6e-11 42.7 0.0 5.5e-08 33.3 0.0 2.3 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KIY65732.1 - 0.0025 17.6 0.0 0.0041 17.0 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TPR_2 PF07719.17 KIY65733.1 - 6.2e-30 100.9 8.4 0.00018 21.3 0.0 8.6 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_1 PF00515.28 KIY65733.1 - 4.7e-28 95.8 3.1 6.6e-06 25.7 0.0 7.9 9 0 0 9 9 7 6 Tetratricopeptide repeat ANAPC3 PF12895.7 KIY65733.1 - 6.2e-24 84.0 3.2 2e-08 34.3 0.0 5.9 4 2 2 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 KIY65733.1 - 3.5e-21 73.6 0.4 0.00036 20.5 0.0 7.1 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_12 PF13424.6 KIY65733.1 - 5.6e-20 71.4 10.9 1.5e-09 38.0 0.1 6.7 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 KIY65733.1 - 2.8e-14 53.5 3.1 1.9e-07 31.6 0.0 5.5 4 1 2 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 KIY65733.1 - 2.5e-13 50.3 1.3 0.015 15.8 0.3 5.9 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 KIY65733.1 - 6.4e-13 48.2 6.7 7.4e-06 25.6 0.1 6.7 4 2 3 7 7 7 3 TPR repeat TPR_17 PF13431.6 KIY65733.1 - 9.2e-12 44.5 2.8 1.6 9.2 0.0 8.7 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_7 PF13176.6 KIY65733.1 - 2.9e-11 42.6 6.5 0.021 14.8 0.0 7.1 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 KIY65733.1 - 5.2e-10 39.3 11.7 0.44 11.5 0.0 8.0 6 3 3 9 9 9 2 Tetratricopeptide repeat TPR_10 PF13374.6 KIY65733.1 - 1.8e-08 34.0 5.2 0.069 13.0 0.0 6.1 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 KIY65733.1 - 2.7e-07 30.8 7.7 0.59 10.9 0.0 6.8 8 0 0 8 8 6 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KIY65733.1 - 2.6e-05 24.2 2.4 0.00067 19.7 0.0 4.1 4 1 1 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat TPR_15 PF13429.6 KIY65733.1 - 6e-05 22.4 0.0 1.5 8.0 0.0 4.9 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 KIY65733.1 - 9.9e-05 22.4 6.7 3.5 7.8 0.0 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KIY65733.1 - 0.0035 16.8 2.5 0.065 12.6 0.2 3.2 2 1 1 3 3 3 1 MalT-like TPR region TPR_21 PF09976.9 KIY65733.1 - 0.016 14.9 0.1 33 4.1 0.0 4.4 4 1 0 4 4 4 0 Tetratricopeptide repeat-like domain Coatomer_E PF04733.14 KIY65733.1 - 0.047 13.1 0.7 1.8 7.9 0.0 3.0 3 1 1 4 4 4 0 Coatomer epsilon subunit TPR_3 PF07720.12 KIY65733.1 - 0.048 13.7 1.3 16 5.6 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.18 KIY65733.1 - 0.085 12.9 0.5 35 4.6 0.0 4.4 5 0 0 5 5 4 0 MIT (microtubule interacting and transport) domain Glyco_hydro_18 PF00704.28 KIY65734.1 - 5.7e-74 249.6 9.7 6.7e-74 249.4 9.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 zf-MYND PF01753.18 KIY65735.1 - 6.9e-10 38.8 11.8 1.1e-09 38.2 11.8 1.4 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KIY65735.1 - 0.00026 21.2 9.8 0.00044 20.5 9.8 1.4 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding DSPc PF00782.20 KIY65736.1 - 5e-27 94.3 0.0 8.7e-27 93.5 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase2 PF03162.13 KIY65736.1 - 0.013 15.0 0.0 0.039 13.5 0.0 1.6 2 0 0 2 2 2 0 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 KIY65736.1 - 0.056 13.4 0.0 0.096 12.6 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family TRAPPC-Trs85 PF12739.7 KIY65736.1 - 0.076 12.0 0.6 0.13 11.2 0.6 1.3 1 0 0 1 1 1 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Rhodanese PF00581.20 KIY65736.1 - 0.13 12.8 0.0 0.47 11.0 0.0 2.0 2 0 0 2 2 2 0 Rhodanese-like domain Y_phosphatase PF00102.27 KIY65736.1 - 0.14 11.7 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Amidohydro_2 PF04909.14 KIY65737.1 - 1.3e-17 64.6 0.0 2e-17 63.9 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.21 KIY65737.1 - 2.7e-06 27.0 0.0 5.1e-05 22.8 0.0 2.0 2 0 0 2 2 2 1 TatD related DNase Sulfotransfer_4 PF17784.1 KIY65737.1 - 0.16 11.8 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 Sulfotransferase domain PAP_assoc PF03828.19 KIY65738.1 - 1.3e-17 63.7 0.1 2.5e-17 62.8 0.1 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KIY65738.1 - 1.6e-05 25.1 0.0 4.3e-05 23.7 0.0 1.7 2 0 0 2 2 2 1 Nucleotidyltransferase domain Polbeta PF18765.1 KIY65738.1 - 0.053 13.6 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase TPR_14 PF13428.6 KIY65738.1 - 1.2 10.1 3.1 1.7 9.7 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat SCP2_2 PF13530.6 KIY65739.1 - 0.065 13.6 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 Sterol carrier protein domain GalP_UDP_tr_C PF02744.17 KIY65739.1 - 0.19 11.5 0.0 0.26 11.0 0.0 1.2 1 0 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, C-terminal domain MFS_1 PF07690.16 KIY65741.1 - 1.2e-18 67.2 37.3 1.2e-18 67.2 37.3 2.5 1 1 1 2 2 2 1 Major Facilitator Superfamily TraG_N PF07916.11 KIY65741.1 - 0.042 12.7 5.7 0.1 11.4 0.4 2.2 2 0 0 2 2 2 0 TraG-like protein, N-terminal region ATP-synt_S1 PF05827.12 KIY65742.1 - 0.084 12.7 1.1 0.15 11.9 1.1 1.5 1 0 0 1 1 1 0 Vacuolar ATP synthase subunit S1 (ATP6S1) 7tm_1 PF00001.21 KIY65743.1 - 0.24 10.7 10.4 0.25 10.6 8.9 1.8 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) DUF4149 PF13664.6 KIY65745.1 - 1.7 9.0 7.1 0.74 10.2 0.4 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4149) adh_short PF00106.25 KIY65747.1 - 1.4e-15 57.3 0.0 3.5e-15 56.0 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIY65747.1 - 1.7e-11 44.2 0.0 3.1e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIY65747.1 - 1.4e-06 28.4 0.0 2.2e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 KR domain POB3_N PF17292.2 KIY65749.1 - 6.4e-29 100.2 7.7 5.9e-28 97.1 0.2 2.8 3 0 0 3 3 3 2 POB3-like N-terminal PH domain SSrecog PF03531.14 KIY65749.1 - 2.8e-23 81.6 0.0 8.7e-23 80.0 0.0 1.9 1 0 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.12 KIY65749.1 - 2.4e-19 69.5 0.0 4.9e-19 68.5 0.0 1.5 1 0 0 1 1 1 1 Histone chaperone Rttp106-like CH PF00307.31 KIY65750.1 - 8.2e-45 151.5 0.0 7.6e-23 80.8 0.0 2.5 2 0 0 2 2 2 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.10 KIY65750.1 - 1.3e-14 54.1 0.1 1.1e-13 51.1 0.0 2.6 3 0 0 3 3 3 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.8 KIY65750.1 - 5.9e-13 48.5 0.1 4.1e-08 32.9 0.1 2.8 2 1 0 2 2 2 2 CAMSAP CH domain EF-hand_6 PF13405.6 KIY65750.1 - 0.01 15.7 0.1 0.039 13.9 0.0 2.1 2 0 0 2 2 1 0 EF-hand domain LUC7 PF03194.15 KIY65750.1 - 0.016 14.8 1.1 0.039 13.6 1.1 1.6 1 0 0 1 1 1 0 LUC7 N_terminus Pox_A28 PF04584.14 KIY65750.1 - 0.058 13.6 1.0 0.15 12.3 1.0 1.7 1 0 0 1 1 1 0 Poxvirus A28 family COG2 PF06148.11 KIY65750.1 - 0.093 12.8 2.8 0.14 12.2 0.5 2.5 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 PC_rep PF01851.22 KIY65750.1 - 0.12 12.9 0.2 26 5.5 0.0 2.9 3 0 0 3 3 2 0 Proteasome/cyclosome repeat Baculo_PEP_C PF04513.12 KIY65750.1 - 0.19 11.7 4.5 0.29 11.2 1.9 2.7 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus CENP-F_leu_zip PF10473.9 KIY65750.1 - 0.75 9.8 5.9 0.17 11.9 1.8 2.1 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Exonuc_VII_L PF02601.15 KIY65750.1 - 5 6.6 7.3 0.88 9.1 1.9 2.0 2 0 0 2 2 2 0 Exonuclease VII, large subunit BST2 PF16716.5 KIY65750.1 - 5.1 7.7 5.4 2.1 9.0 0.7 2.6 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 Med9 PF07544.13 KIY65750.1 - 7.9 6.7 6.5 8.6 6.5 1.5 3.3 3 1 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 p450 PF00067.22 KIY65751.1 - 2.8e-63 214.3 0.6 9.1e-63 212.6 0.6 1.7 1 1 0 1 1 1 1 Cytochrome P450 zf-4CXXC_R1 PF10497.9 KIY65751.1 - 7.9e-08 32.4 15.0 2.2e-07 31.0 11.8 2.4 2 0 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 BORCS7 PF16088.5 KIY65752.1 - 0.017 15.4 2.9 0.017 15.4 2.9 3.5 4 3 0 4 4 4 0 BLOC-1-related complex sub-unit 7 DUF883 PF05957.13 KIY65752.1 - 0.032 14.8 3.7 0.032 14.8 3.7 6.7 1 1 5 6 6 6 0 Bacterial protein of unknown function (DUF883) GAS PF13851.6 KIY65752.1 - 1.6 8.1 70.9 0.72 9.2 17.0 4.0 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding Filament PF00038.21 KIY65752.1 - 3.2 7.2 71.4 0.65 9.5 24.8 4.0 1 1 3 4 4 4 0 Intermediate filament protein MFS_1 PF07690.16 KIY65753.1 - 9.8e-17 60.9 40.7 9.8e-17 60.9 40.7 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily EMC3_TMCO1 PF01956.16 KIY65753.1 - 0.016 14.9 0.8 0.031 14.0 0.8 1.3 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Glutaredoxin PF00462.24 KIY65754.1 - 2.8e-15 56.3 0.0 4.1e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_3 PF13192.6 KIY65754.1 - 0.00057 19.9 0.0 0.00099 19.1 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin domain DUF836 PF05768.14 KIY65754.1 - 0.0028 18.0 0.0 0.0039 17.6 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Toxin-deaminase PF14424.6 KIY65754.1 - 0.0035 17.4 0.2 0.0049 17.0 0.2 1.2 1 0 0 1 1 1 1 The BURPS668_1122 family of deaminases Filamin PF00630.19 KIY65754.1 - 0.029 15.2 0.1 0.035 14.9 0.1 1.1 1 0 0 1 1 1 0 Filamin/ABP280 repeat Thioredoxin_2 PF13098.6 KIY65754.1 - 0.096 13.1 0.0 0.13 12.7 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain Ribosomal_L33 PF00471.20 KIY65754.1 - 0.11 13.0 0.1 0.18 12.3 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein L33 MatE PF01554.18 KIY65757.1 - 6.3e-51 172.2 30.4 3.5e-30 104.8 9.4 2.5 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 KIY65757.1 - 2.2e-08 34.3 5.5 2.2e-08 34.3 5.5 3.5 4 1 0 4 4 4 1 Polysaccharide biosynthesis C-terminal domain HemY_N PF07219.13 KIY65757.1 - 1.3 9.3 5.2 20 5.4 0.4 3.8 3 0 0 3 3 3 0 HemY protein N-terminus Melibiase_2 PF16499.5 KIY65758.1 - 2e-57 194.6 1.1 2.8e-57 194.0 1.1 1.2 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 KIY65758.1 - 3.3e-14 52.7 0.2 8e-14 51.5 0.2 1.7 1 0 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 KIY65758.1 - 7.1e-06 25.2 0.0 1.1e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Melibiase DJ-1_PfpI PF01965.24 KIY65759.1 - 9.2e-12 45.1 0.0 1.2e-11 44.7 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family PHD PF00628.29 KIY65764.1 - 2e-05 24.4 12.2 3.7e-05 23.5 12.2 1.5 1 0 0 1 1 1 1 PHD-finger F-box-like PF12937.7 KIY65766.1 - 0.0014 18.5 5.4 0.006 16.5 2.4 3.0 2 0 0 2 2 2 1 F-box-like TctA PF01970.16 KIY65767.1 - 0.008 14.9 1.1 0.011 14.5 1.1 1.2 1 0 0 1 1 1 1 Tripartite tricarboxylate transporter TctA family CoA_transf_3 PF02515.17 KIY65768.1 - 1.5e-61 208.5 0.0 1.7e-61 208.4 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III zf-CCCH PF00642.24 KIY65770.1 - 0.0059 16.5 0.7 0.013 15.4 0.7 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KIY65770.1 - 0.085 12.9 1.2 0.17 12.0 1.2 1.6 1 0 0 1 1 1 0 Zinc finger domain EST1_DNA_bind PF10373.9 KIY65771.1 - 4.9e-09 36.1 0.0 2.1e-06 27.4 0.0 2.2 2 0 0 2 2 2 2 Est1 DNA/RNA binding domain Plavaka PF18759.1 KIY65772.1 - 5.5e-113 377.4 0.0 1e-112 376.5 0.0 1.5 2 0 0 2 2 2 1 Plavaka transposase p450 PF00067.22 KIY65773.1 - 2.7e-15 56.1 0.0 6.2e-15 54.9 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Glyco_hydro_20 PF00728.22 KIY65773.1 - 0.2 11.0 0.0 0.22 10.9 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 20, catalytic domain DEAD PF00270.29 KIY65774.1 - 9.3e-15 54.8 0.0 3.6e-14 52.9 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 KIY65774.1 - 0.0057 16.7 0.0 0.013 15.5 0.0 1.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KIY65774.1 - 0.018 15.4 0.0 0.14 12.5 0.0 2.1 2 0 0 2 2 2 0 Helicase conserved C-terminal domain Peptidase_S64 PF08192.11 KIY65775.1 - 0.0055 15.3 0.0 0.11 11.0 0.0 2.1 2 0 0 2 2 2 2 Peptidase family S64 DUF4551 PF15087.6 KIY65777.1 - 0.0092 14.9 0.4 0.01 14.7 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4551) BPD_transp_2 PF02653.16 KIY65777.1 - 0.016 14.3 0.3 0.02 14.0 0.3 1.0 1 0 0 1 1 1 0 Branched-chain amino acid transport system / permease component Profilin PF00235.19 KIY65778.1 - 3.7e-46 156.5 0.1 4.1e-46 156.4 0.1 1.0 1 0 0 1 1 1 1 Profilin HK PF02110.15 KIY65783.1 - 2.7e-75 252.9 2.0 4.2e-75 252.3 2.0 1.3 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.17 KIY65783.1 - 1.9e-54 183.8 0.2 3.4e-54 182.9 0.2 1.4 1 0 0 1 1 1 1 Thiamine monophosphate synthase VirC1 PF07015.11 KIY65783.1 - 0.04 13.2 0.3 0.56 9.5 0.2 2.1 2 0 0 2 2 2 0 VirC1 protein SabA_adhesion PF18304.1 KIY65783.1 - 0.045 13.0 0.1 0.084 12.1 0.1 1.4 1 0 0 1 1 1 0 SabA N-terminal extracellular adhesion domain AMP-binding PF00501.28 KIY65785.1 - 1.9e-48 165.1 0.0 2.7e-48 164.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Hexapep PF00132.24 KIY65785.1 - 9.6e-10 37.8 6.2 0.027 14.2 0.1 7.0 7 1 0 7 7 7 4 Bacterial transferase hexapeptide (six repeats) PP-binding PF00550.25 KIY65785.1 - 1.1e-09 38.5 0.6 2.3e-09 37.5 0.0 1.8 2 0 0 2 2 2 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KIY65785.1 - 0.0054 17.7 0.0 0.54 11.3 0.0 2.6 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Hexapep_2 PF14602.6 KIY65785.1 - 0.0095 15.7 10.9 2.3 8.0 0.3 5.5 5 1 1 6 6 6 3 Hexapeptide repeat of succinyl-transferase 4HBT_2 PF13279.6 KIY65786.1 - 3.1e-15 56.7 0.0 4.6e-15 56.2 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 KIY65786.1 - 2.9e-05 24.4 0.0 5.4e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily Acyl-ACP_TE PF01643.17 KIY65786.1 - 0.0017 17.7 0.0 0.0092 15.3 0.0 1.9 2 0 0 2 2 2 1 Acyl-ACP thioesterase Chromo PF00385.24 KIY65788.1 - 2.9e-05 23.9 3.3 5.8e-05 22.9 3.3 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain F-box-like PF12937.7 KIY65789.1 - 4.6e-09 36.0 2.2 6.6e-09 35.5 0.1 2.4 2 0 0 2 2 2 1 F-box-like F-box-like_2 PF13013.6 KIY65789.1 - 0.00076 19.4 0.1 0.0027 17.6 0.1 1.9 1 0 0 1 1 1 1 F-box-like domain LRR_4 PF12799.7 KIY65789.1 - 0.024 15.1 2.7 6.2 7.4 0.1 4.2 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KIY65789.1 - 0.053 13.3 0.7 3 7.7 0.1 3.0 2 0 0 2 2 2 0 Leucine rich repeat Hist_deacetyl PF00850.19 KIY65790.1 - 3.5e-78 263.2 0.0 4.3e-78 262.9 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain HNH_2 PF13391.6 KIY65791.1 - 0.13 12.4 0.2 1.6 8.9 0.0 2.3 2 0 0 2 2 2 0 HNH endonuclease AAA PF00004.29 KIY65792.1 - 2.7e-95 315.8 0.0 3.1e-46 157.1 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KIY65792.1 - 1.9e-24 85.2 9.5 1.7e-12 46.9 0.4 3.2 3 0 0 3 3 3 2 AAA+ lid domain CDC48_N PF02359.18 KIY65792.1 - 7.1e-19 67.8 0.2 2.9e-18 65.8 0.2 2.0 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 KIY65792.1 - 3e-14 53.0 0.0 1.6e-05 24.7 0.0 3.1 3 1 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KIY65792.1 - 2e-13 50.8 0.0 1.6e-07 31.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) CDC48_2 PF02933.17 KIY65792.1 - 2.6e-12 46.3 0.0 5.4e-12 45.3 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_33 PF13671.6 KIY65792.1 - 6.3e-12 45.9 0.0 4.9e-06 26.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 KIY65792.1 - 2.3e-11 43.9 0.1 4.2e-05 23.6 0.1 3.6 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KIY65792.1 - 5e-10 40.0 0.0 0.0019 18.6 0.0 4.2 2 2 0 2 2 2 2 AAA ATPase domain TIP49 PF06068.13 KIY65792.1 - 1.9e-09 37.2 0.1 0.0016 17.7 0.1 2.5 2 1 0 2 2 2 2 TIP49 P-loop domain AAA_22 PF13401.6 KIY65792.1 - 4.5e-09 36.7 0.1 0.026 14.8 0.0 3.9 2 2 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 KIY65792.1 - 8.5e-08 31.8 0.4 0.0055 16.1 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 KIY65792.1 - 2.7e-07 31.2 0.0 0.009 16.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 KIY65792.1 - 3.5e-07 30.1 0.0 0.019 14.7 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein Vps4_C PF09336.10 KIY65792.1 - 3.7e-07 30.0 0.2 1.4e-05 25.0 0.0 2.9 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain RNA_helicase PF00910.22 KIY65792.1 - 1.4e-06 28.7 0.0 0.023 15.1 0.0 2.9 2 0 0 2 2 2 2 RNA helicase AAA_14 PF13173.6 KIY65792.1 - 1.4e-06 28.4 0.0 0.024 14.7 0.0 2.9 3 0 0 3 3 2 2 AAA domain ATPase PF06745.13 KIY65792.1 - 1.6e-06 27.6 0.1 0.4 10.0 0.0 3.4 3 0 0 3 3 3 2 KaiC AAA_7 PF12775.7 KIY65792.1 - 2.2e-06 27.3 0.0 0.01 15.3 0.0 2.8 2 1 0 2 2 2 2 P-loop containing dynein motor region AAA_25 PF13481.6 KIY65792.1 - 3.7e-06 26.7 0.4 0.39 10.3 0.0 3.5 2 1 0 3 3 3 2 AAA domain Parvo_NS1 PF01057.17 KIY65792.1 - 5.9e-06 25.6 0.1 0.0055 15.8 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_28 PF13521.6 KIY65792.1 - 1.1e-05 25.8 0.0 0.073 13.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 KIY65792.1 - 1.9e-05 24.5 0.1 0.18 11.5 0.0 3.0 3 0 0 3 3 2 2 AAA domain DUF815 PF05673.13 KIY65792.1 - 2e-05 23.9 0.0 0.0063 15.7 0.0 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 KIY65792.1 - 2.1e-05 24.3 0.0 0.38 10.5 0.0 3.1 2 1 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.27 KIY65792.1 - 3e-05 24.6 0.0 0.15 12.6 0.0 3.5 2 1 0 2 2 2 1 ABC transporter AAA_17 PF13207.6 KIY65792.1 - 0.00011 22.7 0.0 0.91 9.9 0.0 2.9 2 0 0 2 2 2 2 AAA domain Bac_DnaA PF00308.18 KIY65792.1 - 0.00011 22.2 0.0 0.4 10.5 0.0 2.4 2 0 0 2 2 2 2 Bacterial dnaA protein TsaE PF02367.17 KIY65792.1 - 0.00016 21.7 0.0 0.16 11.9 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ResIII PF04851.15 KIY65792.1 - 0.00016 21.7 0.0 0.12 12.4 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit PhoH PF02562.16 KIY65792.1 - 0.00019 21.0 0.3 0.68 9.3 0.1 2.4 2 0 0 2 2 2 2 PhoH-like protein AAA_3 PF07726.11 KIY65792.1 - 0.00022 21.1 0.0 0.56 10.1 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 KIY65792.1 - 0.00085 19.2 0.8 0.89 9.3 0.0 2.8 3 0 0 3 3 2 1 AAA domain NACHT PF05729.12 KIY65792.1 - 0.00087 19.2 0.1 0.21 11.5 0.0 2.9 3 0 0 3 3 3 1 NACHT domain Viral_helicase1 PF01443.18 KIY65792.1 - 0.0014 18.4 0.0 0.15 11.8 0.0 2.6 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 KIY65792.1 - 0.0017 18.2 0.7 1.4 8.6 0.0 2.8 3 0 0 3 3 2 1 AAA domain ATPase_2 PF01637.18 KIY65792.1 - 0.0017 18.3 0.1 2.8 7.8 0.0 3.4 3 1 0 3 3 2 1 ATPase domain predominantly from Archaea DUF2075 PF09848.9 KIY65792.1 - 0.0029 16.9 0.0 1.3 8.1 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 KIY65792.1 - 0.003 17.9 2.6 3 8.2 0.0 4.1 5 1 0 6 6 4 1 AAA domain Zeta_toxin PF06414.12 KIY65792.1 - 0.0032 16.8 0.0 2 7.6 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin Sigma54_activ_2 PF14532.6 KIY65792.1 - 0.0039 17.3 0.0 3.7 7.7 0.0 2.9 3 0 0 3 3 2 0 Sigma-54 interaction domain T2SSE PF00437.20 KIY65792.1 - 0.0086 15.2 0.0 0.31 10.0 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein NB-ARC PF00931.22 KIY65792.1 - 0.01 15.1 0.0 0.65 9.1 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain NTPase_1 PF03266.15 KIY65792.1 - 0.013 15.4 1.6 3.6 7.5 0.0 4.1 4 0 0 4 4 4 0 NTPase Molydop_binding PF01568.21 KIY65792.1 - 0.013 15.5 0.0 0.028 14.5 0.0 1.5 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain UFD1 PF03152.14 KIY65792.1 - 0.013 15.0 0.0 0.03 13.8 0.0 1.5 1 1 0 1 1 1 0 Ubiquitin fusion degradation protein UFD1 IPT PF01745.16 KIY65792.1 - 0.021 14.2 0.0 2.3 7.5 0.0 2.2 2 0 0 2 2 2 0 Isopentenyl transferase Cytidylate_kin PF02224.18 KIY65792.1 - 0.028 14.2 0.0 4.3 7.0 0.0 2.8 2 0 0 2 2 2 0 Cytidylate kinase KAP_NTPase PF07693.14 KIY65792.1 - 0.035 13.3 0.0 0.6 9.3 0.0 2.5 2 1 0 3 3 3 0 KAP family P-loop domain AFG1_ATPase PF03969.16 KIY65792.1 - 0.063 12.2 0.0 5.9 5.7 0.0 2.2 2 0 0 2 2 2 0 AFG1-like ATPase Cytidylate_kin2 PF13189.6 KIY65792.1 - 0.12 12.5 0.3 2.3 8.3 0.0 2.6 3 0 0 3 3 2 0 Cytidylate kinase-like family Hydin_ADK PF17213.3 KIY65792.1 - 0.16 12.3 1.2 21 5.3 0.0 3.6 4 0 0 4 4 4 0 Hydin Adenylate kinase-like domain Zot PF05707.12 KIY65792.1 - 0.18 11.4 0.0 6.7 6.3 0.0 2.9 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_6 PF12774.7 KIY65792.1 - 0.19 10.7 0.1 11 4.9 0.0 2.4 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region CAP_GLY PF01302.25 KIY65793.1 - 3.2e-26 91.1 1.4 5.3e-26 90.4 1.4 1.4 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.6 KIY65793.1 - 3.9e-20 72.1 0.0 1.5e-19 70.2 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin-like domain ubiquitin PF00240.23 KIY65793.1 - 0.035 13.9 0.0 0.077 12.8 0.0 1.7 1 1 0 1 1 1 0 Ubiquitin family F-box-like PF12937.7 KIY65794.1 - 0.00016 21.5 0.3 0.00047 20.0 0.1 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIY65794.1 - 0.0019 18.0 0.1 0.01 15.7 0.0 2.3 2 0 0 2 2 2 1 F-box domain LRR_1 PF00560.33 KIY65794.1 - 0.065 13.8 0.1 14 6.8 0.0 3.5 2 0 0 2 2 2 0 Leucine Rich Repeat LRR_6 PF13516.6 KIY65794.1 - 0.19 11.9 0.1 18 5.7 0.0 3.4 3 0 0 3 3 3 0 Leucine Rich repeat TFIIS_C PF01096.18 KIY65795.1 - 4.7e-21 74.3 5.6 4.7e-21 74.3 5.6 2.6 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 KIY65795.1 - 1.1e-08 34.8 0.6 1.1e-08 34.8 0.6 2.6 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.7 KIY65795.1 - 5.4e-06 26.3 5.7 0.0054 16.7 1.2 2.3 2 0 0 2 2 2 2 Transposase zinc-ribbon domain PhnA_Zn_Ribbon PF08274.12 KIY65795.1 - 0.0086 16.0 8.7 0.17 11.9 0.3 3.2 3 0 0 3 3 3 2 PhnA Zinc-Ribbon TF_Zn_Ribbon PF08271.12 KIY65795.1 - 0.091 12.3 4.0 0.74 9.4 2.0 2.9 2 1 1 3 3 3 0 TFIIB zinc-binding Zn-ribbon_8 PF09723.10 KIY65795.1 - 0.32 11.2 6.1 13 6.0 0.5 3.9 4 0 0 4 4 4 0 Zinc ribbon domain DUF3797 PF12677.7 KIY65795.1 - 0.36 10.7 7.1 6.2 6.8 0.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF3797) zinc-ribbons_6 PF07191.12 KIY65795.1 - 0.72 9.9 10.8 7.9e+02 0.1 10.8 3.0 1 1 0 1 1 1 0 zinc-ribbons zf-TFIIB PF13453.6 KIY65795.1 - 2.5 7.5 8.6 0.31 10.4 0.3 2.8 2 1 0 2 2 2 0 Transcription factor zinc-finger zinc_ribbon_4 PF13717.6 KIY65795.1 - 3.4 7.6 10.4 2.4 8.1 0.5 3.7 4 0 0 4 4 4 0 zinc-ribbon domain zinc_ribbon_15 PF17032.5 KIY65795.1 - 6 7.7 10.7 1.7e+02 3.0 10.6 2.7 1 1 1 2 2 2 0 zinc-ribbon family SPRY PF00622.28 KIY65796.1 - 9.8e-13 48.3 0.0 1.5e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 SPRY domain ADH_zinc_N PF00107.26 KIY65797.1 - 2.8e-11 43.5 0.1 5.3e-11 42.6 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIY65797.1 - 1.7e-10 40.8 0.0 1e-09 38.2 0.0 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KIY65797.1 - 0.00072 20.6 0.0 0.0015 19.6 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Semialdhyde_dh PF01118.24 KIY65797.1 - 0.0013 19.2 0.1 0.0018 18.7 0.1 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 KIY65798.1 - 6.5e-12 45.6 0.1 1e-11 45.0 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIY65798.1 - 2.4e-09 37.0 0.0 1.2e-08 34.8 0.0 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Semialdhyde_dh PF01118.24 KIY65798.1 - 0.0009 19.7 0.1 0.0017 18.8 0.1 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.6 KIY65798.1 - 0.011 16.8 0.0 0.018 16.1 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase F-box-like PF12937.7 KIY65799.1 - 0.0001 22.1 0.3 0.00093 19.0 0.2 2.8 2 1 0 2 2 2 1 F-box-like DAGAT PF03982.13 KIY65800.1 - 6.3e-95 317.5 0.0 9e-95 317.0 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase ADH_zinc_N PF00107.26 KIY65801.1 - 1.2e-12 48.0 0.1 4.4e-12 46.1 0.1 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIY65801.1 - 6.6e-11 42.1 0.0 9.9e-10 38.3 0.0 2.4 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KIY65801.1 - 7.8e-05 23.7 0.0 0.00018 22.5 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase MFS_1 PF07690.16 KIY65803.1 - 8.6e-30 103.8 33.2 1.3e-29 103.3 33.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily F-box-like PF12937.7 KIY65804.1 - 3.7e-07 29.9 0.2 1.7e-06 27.8 0.2 2.3 1 0 0 1 1 1 1 F-box-like DPBB_1 PF03330.18 KIY65805.1 - 4.5e-05 23.6 0.1 7e-05 23.0 0.1 1.4 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 KIY65805.1 - 0.0043 16.9 0.1 0.0053 16.6 0.1 1.1 1 0 0 1 1 1 1 Barwin family F-box-like PF12937.7 KIY65807.1 - 0.017 15.0 0.3 0.04 13.8 0.3 1.6 1 0 0 1 1 1 0 F-box-like MFS_1 PF07690.16 KIY65808.1 - 1.5e-38 132.7 46.6 7.4e-29 100.8 10.7 2.7 1 1 1 3 3 3 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KIY65808.1 - 5.2e-10 38.7 17.8 2.1e-06 26.8 0.4 3.6 2 2 1 4 4 4 3 MFS_1 like family Sugar_tr PF00083.24 KIY65808.1 - 5.8e-09 35.3 4.8 5.8e-09 35.3 4.8 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.6 KIY65808.1 - 7.9e-09 34.6 28.2 6.5e-06 25.0 15.1 2.3 2 1 0 2 2 2 2 MFS/sugar transport protein OATP PF03137.20 KIY65808.1 - 9.1e-06 24.2 1.6 9.1e-06 24.2 1.6 2.8 2 1 1 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family UNC-93 PF05978.16 KIY65808.1 - 0.72 9.6 7.0 0.07 12.8 1.1 2.2 2 0 0 2 2 2 0 Ion channel regulatory protein UNC-93 SecE PF00584.20 KIY65808.1 - 2.9 7.9 6.0 5.2 7.1 0.3 3.1 2 0 0 2 2 2 0 SecE/Sec61-gamma subunits of protein translocation complex F-box-like PF12937.7 KIY65810.1 - 9e-09 35.1 0.1 2.1e-08 33.9 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY65810.1 - 0.0013 18.6 0.4 2.6 8.0 0.1 3.2 3 1 0 3 3 3 2 F-box domain FTSW_RODA_SPOVE PF01098.19 KIY65810.1 - 0.061 12.3 0.3 0.088 11.8 0.3 1.2 1 0 0 1 1 1 0 Cell cycle protein TPR_2 PF07719.17 KIY65811.1 - 1e-06 28.4 0.4 0.064 13.4 0.2 2.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KIY65811.1 - 1.3e-06 28.0 0.3 0.051 13.4 0.2 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 KIY65811.1 - 0.00014 22.1 0.1 0.53 10.6 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 KIY65811.1 - 0.042 14.7 0.0 1.8 9.6 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3856 PF12968.7 KIY65811.1 - 0.11 12.6 0.2 0.19 11.8 0.2 1.6 1 1 0 1 1 1 0 Domain of Unknown Function (DUF3856) Baculo_LEF-11 PF06385.12 KIY65811.1 - 0.13 12.8 0.0 0.31 11.6 0.0 1.6 1 0 0 1 1 1 0 Baculovirus LEF-11 protein TPR_11 PF13414.6 KIY65811.1 - 0.19 11.5 0.6 1.6 8.5 0.2 2.3 2 0 0 2 2 2 0 TPR repeat TPR_16 PF13432.6 KIY65811.1 - 0.27 11.9 1.8 3.1 8.5 0.2 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat RINGv PF12906.7 KIY65813.1 - 5e-16 58.6 7.7 8.7e-16 57.8 7.7 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 KIY65813.1 - 0.019 15.3 9.5 0.032 14.6 9.5 1.4 1 0 0 1 1 1 0 Ring finger domain zf-ANAPC11 PF12861.7 KIY65813.1 - 1.2 9.2 4.4 2.5 8.2 4.4 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 KIY65813.1 - 1.7 8.5 7.4 3 7.7 7.4 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Pec_lyase_C PF00544.19 KIY65815.1 - 5.7e-47 160.0 4.9 8e-47 159.5 4.9 1.2 1 0 0 1 1 1 1 Pectate lyase Flagellar_put PF12611.8 KIY65815.1 - 3.4 7.5 5.7 10 6.0 0.7 3.0 2 1 0 2 2 2 0 Putative flagellar EBP PF05241.12 KIY65816.1 - 0.014 14.8 5.6 0.02 14.4 5.6 1.2 1 0 0 1 1 1 0 Emopamil binding protein F-box-like PF12937.7 KIY65817.1 - 0.0025 17.7 0.3 0.0055 16.6 0.3 1.6 1 0 0 1 1 1 1 F-box-like DLH PF01738.18 KIY65818.1 - 4.2e-24 85.3 0.0 4.8e-24 85.1 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 KIY65818.1 - 0.014 15.1 0.0 0.28 10.8 0.1 2.3 1 1 1 2 2 2 0 alpha/beta hydrolase fold MFS_1 PF07690.16 KIY65819.1 - 7.3e-43 146.8 35.2 1e-42 146.4 35.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIY65819.1 - 9.5e-13 47.8 5.7 9.5e-13 47.8 5.7 2.3 2 2 0 2 2 2 1 Sugar (and other) transporter DEAD PF00270.29 KIY65820.1 - 1.2e-45 155.4 0.0 1.9e-45 154.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIY65820.1 - 2.4e-29 101.9 0.0 5.9e-29 100.7 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIY65820.1 - 0.015 15.3 0.0 0.042 13.9 0.0 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit CMS1 PF14617.6 KIY65820.1 - 0.099 12.0 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit ERCC3_RAD25_C PF16203.5 KIY65820.1 - 0.22 10.7 0.0 0.34 10.1 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase SdpI PF13630.6 KIY65821.1 - 0.33 11.1 0.0 0.33 11.1 0.0 3.7 2 2 1 3 3 3 0 SdpI/YhfL protein family Cytochrom_B_C PF00032.17 KIY65821.1 - 3.8 7.9 7.7 0.96 9.8 0.7 2.9 2 1 1 3 3 3 0 Cytochrome b(C-terminal)/b6/petD PCI PF01399.27 KIY65822.1 - 0.00012 22.5 0.2 0.00026 21.5 0.2 1.5 1 0 0 1 1 1 1 PCI domain Arginosuc_synth PF00764.19 KIY65823.1 - 1.6e-153 511.6 0.0 1.9e-153 511.4 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 KIY65823.1 - 0.00031 20.3 0.0 0.00066 19.2 0.0 1.5 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 KIY65823.1 - 0.013 14.4 0.0 0.02 13.7 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase Mito_carr PF00153.27 KIY65824.1 - 1.3e-45 153.3 0.2 1.2e-15 57.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3082 PF11282.8 KIY65824.1 - 0.14 12.4 2.2 0.5 10.6 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3082) Abhydrolase_1 PF00561.20 KIY65828.1 - 3.9e-18 66.0 0.1 6.6e-18 65.3 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 KIY65828.1 - 1.3e-08 34.9 0.0 2.5e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein SNO PF01174.19 KIY65831.1 - 8.2e-50 169.3 0.0 2.9e-49 167.5 0.0 1.7 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 KIY65831.1 - 4.8e-08 32.8 0.0 6.4e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_S51 PF03575.17 KIY65831.1 - 3.2e-05 23.7 0.0 4.7e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S51 DJ-1_PfpI PF01965.24 KIY65831.1 - 0.036 13.9 0.0 0.057 13.2 0.0 1.2 1 0 0 1 1 1 0 DJ-1/PfpI family Epimerase PF01370.21 KIY65832.1 - 3.4e-16 59.4 0.0 4.8e-16 59.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KIY65832.1 - 2.2e-11 43.3 0.0 3.7e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KIY65832.1 - 1.1e-09 38.4 0.1 1e-08 35.3 0.1 2.2 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KIY65832.1 - 2.9e-07 30.3 0.1 1e-06 28.5 0.1 1.9 2 0 0 2 2 2 1 NmrA-like family NAD_binding_4 PF07993.12 KIY65832.1 - 1.6e-06 27.5 0.0 1.7e-05 24.2 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 KIY65832.1 - 0.0001 21.5 0.0 0.00032 20.0 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KIY65832.1 - 0.00019 21.0 0.0 0.00034 20.1 0.0 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase KR PF08659.10 KIY65832.1 - 0.0013 18.7 0.0 0.0023 17.9 0.0 1.5 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 KIY65832.1 - 0.14 11.6 0.1 0.25 10.8 0.1 1.4 1 0 0 1 1 1 0 short chain dehydrogenase adh_short PF00106.25 KIY65833.1 - 1e-13 51.2 0.0 5e-12 45.7 0.1 2.5 1 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIY65833.1 - 0.0016 18.0 0.0 0.003 17.2 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Shikimate_DH PF01488.20 KIY65833.1 - 0.013 15.5 0.0 0.065 13.3 0.0 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DUF2263 PF10021.9 KIY65834.1 - 6.9e-45 153.0 0.0 9.5e-45 152.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Got1 PF04178.12 KIY65835.1 - 3.5e-18 66.1 15.8 4.6e-18 65.7 15.8 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family PhaG_MnhG_YufB PF03334.14 KIY65835.1 - 2.4 8.5 11.0 0.26 11.5 4.2 2.2 1 1 1 2 2 2 0 Na+/H+ antiporter subunit MFS_1 PF07690.16 KIY65836.1 - 3.5e-18 65.7 31.7 1e-17 64.1 28.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Ribosomal_60s PF00428.19 KIY65837.1 - 8.6 7.0 13.6 25 5.5 13.6 1.7 1 1 1 2 2 2 0 60s Acidic ribosomal protein WD40 PF00400.32 KIY65838.1 - 2.8e-40 135.6 21.7 1.6e-08 35.1 0.2 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY65838.1 - 1.9e-09 37.7 0.8 0.087 13.1 0.0 4.9 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIY65838.1 - 0.001 17.8 7.2 0.0038 15.9 0.2 3.5 3 1 2 5 5 5 2 Nucleoporin Nup120/160 PD40 PF07676.12 KIY65838.1 - 0.0017 18.2 1.2 5.9 7.0 0.0 4.6 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 KIY65838.1 - 0.0022 16.6 0.2 0.12 10.8 0.3 2.3 2 1 0 2 2 2 1 Cytochrome D1 heme domain DUF1416 PF07210.12 KIY65838.1 - 0.073 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1416) WD40_like PF17005.5 KIY65838.1 - 0.21 10.9 0.0 14 4.8 0.0 2.2 2 0 0 2 2 2 0 WD40-like domain BTB PF00651.31 KIY65839.1 - 2e-06 28.0 0.0 3e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KIY65840.1 - 2.7e-06 27.6 0.0 5.1e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain DarT PF14487.6 KIY65840.1 - 0.17 11.7 0.0 0.39 10.5 0.0 1.5 2 0 0 2 2 2 0 ssDNA thymidine ADP-ribosyltransferase, DarT TMEM223 PF14640.6 KIY65841.1 - 0.00013 22.2 0.0 0.00017 21.8 0.0 1.1 1 0 0 1 1 1 1 Transmembrane protein 223 DUF2905 PF11146.8 KIY65842.1 - 0.064 13.4 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2905) WD40 PF00400.32 KIY65843.1 - 6.2e-20 71.2 18.1 0.0009 20.0 0.0 7.2 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY65843.1 - 3.1e-12 46.6 1.6 0.0046 17.2 0.1 4.4 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain IU_nuc_hydro PF01156.19 KIY65844.1 - 2.8e-55 188.1 0.0 3.4e-55 187.8 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase bZIP_1 PF00170.21 KIY65845.1 - 8e-07 29.1 2.9 1.6e-06 28.1 2.9 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KIY65845.1 - 0.0024 17.9 2.6 0.0042 17.2 2.6 1.4 1 0 0 1 1 1 1 Basic region leucine zipper Herpes_BLRF2 PF05812.12 KIY65845.1 - 0.0065 16.6 0.3 0.011 15.8 0.3 1.4 1 0 0 1 1 1 1 Herpesvirus BLRF2 protein DUF773 PF05600.12 KIY65845.1 - 0.018 13.8 0.1 0.022 13.5 0.1 1.1 1 0 0 1 1 1 0 CDK5 regulatory subunit-associated protein 3 HALZ PF02183.18 KIY65845.1 - 0.025 14.8 0.4 0.047 13.9 0.4 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper TSC22 PF01166.18 KIY65845.1 - 0.042 14.2 1.0 0.059 13.7 0.2 1.6 2 0 0 2 2 2 0 TSC-22/dip/bun family Shugoshin_N PF07558.11 KIY65845.1 - 0.051 13.4 0.5 0.086 12.7 0.5 1.3 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region Fungal_TACC PF12709.7 KIY65845.1 - 0.052 14.0 0.0 0.092 13.2 0.0 1.5 1 0 0 1 1 1 0 Fungal Transforming acidic coiled-coil (TACC) proteins DUF648 PF04890.13 KIY65845.1 - 0.14 11.9 0.0 0.17 11.6 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF648) CASP_C PF08172.12 KIY65845.1 - 0.29 10.4 2.4 0.51 9.6 2.4 1.3 1 0 0 1 1 1 0 CASP C terminal Nudix_N_2 PF14803.6 KIY65848.1 - 0.12 12.4 2.5 11 6.1 0.2 2.4 2 0 0 2 2 2 0 Nudix N-terminal DUF35_N PF12172.8 KIY65848.1 - 1.1 9.1 6.7 0.52 10.3 0.9 2.6 3 0 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) BTB PF00651.31 KIY65849.1 - 6.3e-06 26.4 0.0 8.4e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KIY65850.1 - 0.0022 18.2 0.0 0.0036 17.5 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain DJ-1_PfpI PF01965.24 KIY65851.1 - 1.1e-18 67.6 0.0 1.2e-18 67.5 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family Cons_hypoth698 PF03601.14 KIY65851.1 - 0.056 12.3 0.2 0.08 11.8 0.2 1.1 1 0 0 1 1 1 0 Conserved hypothetical protein 698 MutS_V PF00488.21 KIY65854.1 - 0.14 12.2 0.0 0.16 12.0 0.0 1.0 1 0 0 1 1 1 0 MutS domain V Herpes_LMP1 PF05297.11 KIY65855.1 - 8.3 5.5 14.0 10 5.2 14.0 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Sorting_nexin PF03700.13 KIY65858.1 - 0.013 16.1 0.5 0.05 14.2 0.0 2.2 2 0 0 2 2 2 0 Sorting nexin, N-terminal domain BRO1 PF03097.18 KIY65859.1 - 2.6e-102 342.5 1.1 4e-102 341.9 1.1 1.3 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 KIY65859.1 - 2.2e-67 227.4 9.1 4.3e-67 226.5 9.1 1.5 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV ING PF12998.7 KIY65859.1 - 0.0089 16.6 4.9 0.017 15.7 0.7 3.1 2 1 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding Trypan_PARP PF05887.11 KIY65859.1 - 0.02 14.8 11.6 0.037 14.0 11.6 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Rx_N PF18052.1 KIY65859.1 - 4.1 7.7 7.9 1.2 9.4 0.3 3.2 3 0 0 3 3 3 0 Rx N-terminal domain Arylesterase PF01731.20 KIY65861.1 - 3.4e-06 27.2 1.3 1.9e-05 24.7 0.4 2.6 2 1 0 2 2 2 1 Arylesterase SGL PF08450.12 KIY65861.1 - 0.00046 19.9 0.0 0.001 18.7 0.0 1.7 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 KIY65861.1 - 0.011 15.8 0.0 0.035 14.2 0.0 1.8 1 0 0 1 1 1 0 Strictosidine synthase Na_Ca_ex PF01699.24 KIY65862.1 - 1.2e-44 151.9 50.1 8.8e-28 97.2 14.7 2.9 3 0 0 3 3 3 2 Sodium/calcium exchanger protein SpoVAB PF13782.6 KIY65862.1 - 0.0096 16.2 5.4 0.038 14.3 5.4 2.1 1 0 0 1 1 1 1 Stage V sporulation protein AB DUF4381 PF14316.6 KIY65862.1 - 0.15 12.3 1.4 1 9.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Asparaginase_2 PF01112.18 KIY65863.1 - 5.7e-69 232.5 0.1 6.7e-53 179.7 0.0 2.1 2 0 0 2 2 2 2 Asparaginase Alpha-amylase PF00128.24 KIY65864.1 - 1.8e-24 87.0 0.0 5.7e-24 85.3 0.0 1.6 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.16 KIY65864.1 - 1.1e-05 23.8 0.0 0.065 11.4 0.0 3.1 3 0 0 3 3 3 3 Glycosyl hydrolase family 70 DUF1939 PF09154.10 KIY65864.1 - 0.00035 20.7 0.0 0.0013 18.9 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1939) Sugar_tr PF00083.24 KIY65865.1 - 3.6e-72 243.7 24.5 4.1e-72 243.5 24.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY65865.1 - 1.6e-20 73.4 34.7 3.1e-19 69.1 24.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily GPI-anchored PF10342.9 KIY65866.1 - 0.019 15.7 0.9 0.019 15.7 0.9 1.9 2 0 0 2 2 2 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family BslA PF17735.1 KIY65866.1 - 0.049 13.6 0.2 0.081 12.9 0.2 1.4 1 0 0 1 1 1 0 Biofilm surface layer A ADH_N_2 PF16884.5 KIY65868.1 - 4.8e-27 94.0 0.0 8.1e-27 93.3 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 KIY65868.1 - 4e-16 59.2 0.1 6e-16 58.6 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KIY65868.1 - 1.6e-08 35.7 0.0 2.8e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.21 KIY65868.1 - 0.089 12.5 0.1 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Mad3_BUB1_I PF08311.12 KIY65869.1 - 1.6e-35 121.7 0.6 2.7e-35 121.0 0.6 1.4 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.25 KIY65869.1 - 6.3e-13 48.7 0.0 1.5e-12 47.4 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY65869.1 - 2.3e-07 30.3 0.0 3.8e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Mad3_BUB1_II PF08171.11 KIY65869.1 - 3.2e-05 24.0 0.0 7.7e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Mad3/BUB1 homology region 2 Mad3_BUB1_I_2 PF17014.5 KIY65869.1 - 0.008 16.3 0.1 0.029 14.5 0.0 1.9 3 0 0 3 3 3 1 Putative Mad3/BUB1 like region 1 protein Kdo PF06293.14 KIY65869.1 - 0.039 13.3 0.0 0.072 12.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ferritin_2 PF13668.6 KIY65870.1 - 1.7e-43 148.0 3.3 2.7e-43 147.4 3.3 1.3 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.17 KIY65870.1 - 0.055 13.9 0.4 0.3 11.5 0.3 2.1 1 1 1 2 2 2 0 Rubrerythrin Isochorismatase PF00857.20 KIY65871.1 - 5.7e-15 55.9 0.0 7.6e-15 55.5 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family Pectate_lyase PF03211.13 KIY65872.1 - 8.3e-86 286.7 6.3 9.4e-86 286.5 6.3 1.0 1 0 0 1 1 1 1 Pectate lyase Cellulase PF00150.18 KIY65873.1 - 3.6e-48 164.4 0.0 4.5e-48 164.1 0.0 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) UPF0016 PF01169.19 KIY65874.1 - 1e-44 150.7 17.2 1.4e-22 79.8 5.0 2.1 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 TauE PF01925.19 KIY65874.1 - 0.0054 16.4 12.3 0.27 10.8 12.3 2.2 1 1 0 1 1 1 1 Sulfite exporter TauE/SafE Cad PF03596.13 KIY65874.1 - 0.013 15.4 0.0 0.028 14.3 0.0 1.5 1 0 0 1 1 1 0 Cadmium resistance transporter DUF1182 PF06681.13 KIY65874.1 - 0.025 14.2 0.4 0.3 10.6 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1182) LysE PF01810.18 KIY65874.1 - 0.64 9.5 13.3 0.57 9.6 2.4 2.4 2 0 0 2 2 2 0 LysE type translocator TerC PF03741.16 KIY65874.1 - 1.3 8.7 6.6 0.92 9.2 0.4 2.4 2 0 0 2 2 2 0 Integral membrane protein TerC family ATP_synt_H PF05493.13 KIY65874.1 - 1.3 9.5 12.6 5.2 7.6 3.1 3.3 2 1 1 3 3 3 0 ATP synthase subunit H DUF4131 PF13567.6 KIY65874.1 - 1.5 8.4 6.8 7.6 6.2 2.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Fungal_trans PF04082.18 KIY65875.1 - 3.1e-13 49.4 0.0 5.1e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY65875.1 - 2.1e-09 37.4 9.8 3.4e-09 36.7 9.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain G-patch_2 PF12656.7 KIY65876.1 - 2.8e-22 78.6 0.1 8.4e-22 77.0 0.1 1.9 1 0 0 1 1 1 1 G-patch domain G-patch PF01585.23 KIY65876.1 - 0.015 15.2 2.2 0.027 14.3 0.7 2.1 2 0 0 2 2 2 0 G-patch domain ORF6C PF10552.9 KIY65876.1 - 0.1 12.7 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 ORF6C domain Alk_phosphatase PF00245.20 KIY65877.1 - 7.7e-66 222.7 0.0 1e-65 222.3 0.0 1.2 1 0 0 1 1 1 1 Alkaline phosphatase Sulfatase PF00884.23 KIY65877.1 - 7.7e-06 25.5 0.0 1.5e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KIY65877.1 - 1.1e-05 25.2 0.0 1.8e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 KIY65877.1 - 0.085 12.2 1.3 0.15 11.4 0.3 1.8 2 0 0 2 2 2 0 Metalloenzyme superfamily DUF229 PF02995.17 KIY65877.1 - 0.25 9.9 0.1 0.39 9.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) DUF2298 PF10060.9 KIY65879.1 - 0.16 10.7 5.7 0.27 9.9 5.7 1.3 1 1 0 1 1 1 0 Uncharacterized membrane protein (DUF2298) DUF2079 PF09852.9 KIY65879.1 - 2.4 6.9 8.3 0.036 12.9 0.7 1.6 3 0 0 3 3 3 0 Predicted membrane protein (DUF2079) DUF996 PF06195.13 KIY65879.1 - 3.7 7.8 12.7 0.55 10.5 5.4 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF996) Yip1 PF04893.17 KIY65880.1 - 1.3e-15 57.5 14.5 1.9e-15 57.0 14.5 1.2 1 0 0 1 1 1 1 Yip1 domain DUF1282 PF06930.12 KIY65880.1 - 0.0032 17.3 8.6 0.0048 16.7 8.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1282) Sad1_UNC PF07738.13 KIY65881.1 - 1.7e-28 99.2 0.0 5.1e-12 46.0 0.0 3.3 3 0 0 3 3 3 3 Sad1 / UNC-like C-terminal Syntaxin_2 PF14523.6 KIY65881.1 - 0.024 15.0 1.6 0.024 15.0 1.6 1.8 2 0 0 2 2 2 0 Syntaxin-like protein Sugarporin_N PF11471.8 KIY65881.1 - 0.033 14.2 3.5 0.63 10.1 0.9 2.9 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension DUF2630 PF10944.8 KIY65881.1 - 0.58 10.6 4.5 4.2 7.9 1.6 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2630) Fib_alpha PF08702.10 KIY65881.1 - 0.84 9.8 3.2 6 7.1 2.7 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Baculo_PEP_C PF04513.12 KIY65881.1 - 1.5 8.8 3.0 1.4 9.0 0.9 1.9 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Exonuc_VII_L PF02601.15 KIY65881.1 - 2 7.9 7.4 0.074 12.6 1.0 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit TPR_MLP1_2 PF07926.12 KIY65881.1 - 3.1 7.8 8.6 7.8 6.6 8.5 1.7 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein YL1_C PF08265.11 KIY65884.1 - 1.8e-15 56.3 1.7 2.8e-15 55.8 1.7 1.3 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain B-block_TFIIIC PF04182.12 KIY65885.1 - 3.6e-07 30.2 0.3 0.00019 21.5 0.0 3.7 4 0 0 4 4 4 1 B-block binding subunit of TFIIIC MarR_2 PF12802.7 KIY65885.1 - 0.016 15.1 0.4 11 6.0 0.0 3.8 4 0 0 4 4 4 0 MarR family SelB-wing_2 PF09106.11 KIY65885.1 - 0.031 14.5 0.0 30 4.9 0.0 4.6 5 0 0 5 5 5 0 Elongation factor SelB, winged helix PRELI PF04707.14 KIY65886.1 - 1.1e-35 122.8 0.0 1.3e-35 122.6 0.0 1.0 1 0 0 1 1 1 1 PRELI-like family ABC_membrane_2 PF06472.15 KIY65887.1 - 1.1e-83 280.8 0.6 1.4e-83 280.4 0.6 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 KIY65887.1 - 2.7e-17 63.6 0.0 5.2e-17 62.7 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KIY65887.1 - 0.00022 21.1 0.0 0.00037 20.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KIY65887.1 - 0.0049 17.4 0.0 0.016 15.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KIY65887.1 - 0.0089 15.7 0.0 0.022 14.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_7 PF12775.7 KIY65887.1 - 0.035 13.6 0.0 0.061 12.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region SMC_N PF02463.19 KIY65887.1 - 0.048 13.1 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Rad17 PF03215.15 KIY65887.1 - 0.049 13.6 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain IstB_IS21 PF01695.17 KIY65887.1 - 0.054 13.2 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_16 PF13191.6 KIY65887.1 - 0.098 13.0 0.1 0.26 11.6 0.1 1.7 1 0 0 1 1 1 0 AAA ATPase domain TnpV PF14198.6 KIY65887.1 - 0.12 12.4 0.1 0.37 10.8 0.1 1.8 1 0 0 1 1 1 0 Transposon-encoded protein TnpV AAA_15 PF13175.6 KIY65887.1 - 0.3 10.7 0.5 0.51 10.0 0.0 1.5 2 0 0 2 2 2 0 AAA ATPase domain NT5C PF06941.12 KIY65888.1 - 1.2e-07 31.8 0.0 2.4e-06 27.5 0.1 2.1 2 0 0 2 2 2 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) NIF PF03031.18 KIY65888.1 - 4.9e-06 26.4 0.0 9.9e-06 25.4 0.0 1.6 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase HAD_2 PF13419.6 KIY65888.1 - 0.0016 18.6 0.0 0.0026 17.9 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD PF12710.7 KIY65888.1 - 0.004 17.6 0.0 0.006 17.0 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.14 KIY65888.1 - 0.017 14.7 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) Pkinase PF00069.25 KIY65889.1 - 5.4e-68 229.2 0.0 8.9e-68 228.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY65889.1 - 7.2e-41 140.2 0.0 1.9e-40 138.8 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY65889.1 - 1.6e-07 30.9 0.0 3.9e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KIY65889.1 - 0.00082 18.3 0.0 0.0016 17.3 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KIY65889.1 - 0.014 14.8 0.2 0.027 13.8 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 KIY65889.1 - 0.034 13.2 0.0 0.074 12.1 0.0 1.5 1 0 0 1 1 1 0 Seadornavirus VP7 Vta1_C PF18097.1 KIY65889.1 - 0.045 13.5 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Vta1 C-terminal domain FTA2 PF13095.6 KIY65889.1 - 0.069 12.8 0.1 0.24 11.0 0.0 1.9 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KIY65889.1 - 0.084 12.8 0.0 0.26 11.1 0.0 1.9 1 0 0 1 1 1 0 Phosphotransferase enzyme family DASH_Duo1 PF08651.10 KIY65889.1 - 0.19 11.5 1.1 0.57 10.0 0.0 2.4 2 0 0 2 2 2 0 DASH complex subunit Duo1 MMR_HSR1_Xtn PF16897.5 KIY65890.1 - 3e-42 143.0 0.6 5.5e-42 142.1 0.6 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 KIY65890.1 - 3e-21 75.6 0.1 9.1e-21 74.1 0.0 1.9 1 1 1 2 2 2 1 50S ribosome-binding GTPase TGS PF02824.21 KIY65890.1 - 1.5e-19 69.7 0.0 2.6e-19 69.0 0.0 1.4 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 KIY65890.1 - 1.8e-12 47.0 0.0 3.5e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KIY65890.1 - 3.9e-05 23.8 0.1 0.34 11.0 0.0 2.5 1 1 1 2 2 2 2 Dynamin family MeaB PF03308.16 KIY65890.1 - 0.003 16.6 0.1 0.048 12.6 0.0 2.3 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 KIY65890.1 - 0.0098 16.3 0.1 0.025 14.9 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.10 KIY65890.1 - 0.011 15.2 0.0 0.02 14.3 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 KIY65890.1 - 0.02 14.8 0.1 0.15 12.0 0.0 2.3 2 1 0 2 2 2 0 RsgA GTPase AAA_28 PF13521.6 KIY65890.1 - 0.03 14.5 0.1 0.064 13.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain MCM PF00493.23 KIY65890.1 - 0.056 12.5 0.2 0.19 10.8 0.0 1.8 2 0 0 2 2 2 0 MCM P-loop domain AAA_22 PF13401.6 KIY65890.1 - 0.068 13.4 0.0 0.16 12.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain Roc PF08477.13 KIY65890.1 - 0.098 12.9 0.0 0.41 10.9 0.0 2.2 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase SGTA_dimer PF16546.5 KIY65891.1 - 4.7e-25 87.1 0.3 4.7e-25 87.1 0.3 1.7 2 0 0 2 2 2 1 Homodimerisation domain of SGTA TPR_1 PF00515.28 KIY65891.1 - 3.3e-19 67.8 2.2 2.4e-06 27.1 0.0 3.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 KIY65891.1 - 5.2e-17 61.3 2.2 3.4e-10 39.4 0.2 2.5 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.17 KIY65891.1 - 7.9e-17 60.0 1.7 4.2e-05 23.3 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 KIY65891.1 - 1e-11 44.0 4.7 0.013 15.6 0.1 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 KIY65891.1 - 5.5e-10 38.9 0.5 0.00064 19.9 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 KIY65891.1 - 1.8e-09 37.6 0.2 0.018 15.8 0.0 3.7 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KIY65891.1 - 6.9e-08 33.0 5.7 1.6e-05 25.5 0.1 2.7 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KIY65891.1 - 2.9e-07 30.7 2.9 0.00087 19.5 1.1 2.8 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 KIY65891.1 - 7.8e-07 28.7 0.2 0.017 15.1 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 KIY65891.1 - 1.6e-06 27.8 0.6 0.061 13.2 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KIY65891.1 - 0.00037 20.9 0.5 1.1 9.8 0.1 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 KIY65891.1 - 0.0044 17.1 0.1 0.18 11.9 0.0 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 KIY65891.1 - 0.0055 17.3 1.5 7.5 7.4 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat DUF4603 PF15376.6 KIY65891.1 - 0.024 12.0 1.5 0.033 11.6 1.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) TPR_15 PF13429.6 KIY65891.1 - 0.045 13.0 0.1 0.073 12.3 0.1 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat BTAD PF03704.17 KIY65891.1 - 0.12 12.8 0.1 1.4 9.3 0.0 2.0 1 1 0 2 2 2 0 Bacterial transcriptional activator domain Prp19 PF08606.11 KIY65892.1 - 1.1e-31 108.6 2.2 1.9e-31 107.9 2.2 1.4 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.32 KIY65892.1 - 3.5e-11 43.4 0.1 0.072 14.0 0.0 5.8 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY65892.1 - 8.2e-08 32.5 0.0 0.32 11.3 0.0 4.3 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain U-box PF04564.15 KIY65892.1 - 7.6e-05 22.8 0.0 0.0002 21.5 0.0 1.7 1 0 0 1 1 1 1 U-box domain Frtz PF11768.8 KIY65892.1 - 0.0013 17.1 0.0 0.0023 16.3 0.0 1.4 1 0 0 1 1 1 1 WD repeat-containing and planar cell polarity effector protein Fritz zf-Nse PF11789.8 KIY65892.1 - 0.0028 17.4 0.0 0.0057 16.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Hira PF07569.11 KIY65892.1 - 0.1 12.3 0.2 2.7 7.6 0.0 2.2 2 0 0 2 2 2 0 TUP1-like enhancer of split DUF4073 PF13285.6 KIY65892.1 - 0.1 12.2 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4073) BCOR PF15808.5 KIY65892.1 - 0.12 12.6 0.3 0.22 11.7 0.1 1.5 2 0 0 2 2 2 0 BCL-6 co-repressor, non-ankyrin-repeat region Myb_DNA-binding PF00249.31 KIY65893.1 - 6.2e-36 122.3 6.9 3.3e-13 49.6 0.0 3.6 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KIY65893.1 - 6.1e-34 116.1 3.1 1.1e-14 54.4 0.2 3.6 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_2 PF08914.11 KIY65893.1 - 0.0013 18.9 0.2 0.033 14.4 0.2 2.9 2 1 1 3 3 3 1 Rap1 Myb domain Rap1_C PF11626.8 KIY65893.1 - 0.014 15.5 2.5 5.7 7.1 0.0 3.2 1 1 2 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain MADF_DNA_bdg PF10545.9 KIY65893.1 - 0.03 14.6 0.7 0.18 12.2 0.4 2.4 3 0 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like zf-C2H2 PF00096.26 KIY65893.1 - 0.097 13.2 5.5 0.4 11.2 1.6 3.3 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIY65893.1 - 0.14 13.1 10.0 12 7.1 0.1 4.9 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 KIY65893.1 - 1.7 8.8 3.7 0.61 10.2 0.7 1.7 2 0 0 2 2 2 0 Aberrant zinc-finger WD40 PF00400.32 KIY65894.1 - 3e-34 116.5 14.1 8.1e-09 36.0 0.4 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY65894.1 - 7.7e-09 35.7 0.1 0.26 11.6 0.1 4.4 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 KIY65894.1 - 0.0028 17.3 0.1 0.47 10.0 0.0 2.8 2 1 1 3 3 3 1 PQQ-like domain Cytochrom_D1 PF02239.16 KIY65894.1 - 0.005 15.4 0.0 1.8 7.0 0.0 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain PD40 PF07676.12 KIY65894.1 - 0.1 12.6 0.4 5.9 6.9 0.2 2.6 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat MCM PF00493.23 KIY65896.1 - 7.1e-96 319.6 0.1 1.1e-95 319.0 0.1 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KIY65896.1 - 7.1e-34 116.4 0.0 1.3e-33 115.6 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KIY65896.1 - 9.2e-23 80.5 2.0 1.7e-22 79.6 2.0 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KIY65896.1 - 4.5e-15 56.1 0.0 1.3e-14 54.7 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KIY65896.1 - 7e-08 32.1 0.1 1.8e-06 27.5 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KIY65896.1 - 0.0055 16.6 0.0 0.018 14.9 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KIY65896.1 - 0.017 14.9 0.1 0.051 13.3 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain TFIIF_alpha PF05793.12 KIY65896.1 - 2.2 6.8 18.3 3.2 6.2 18.3 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) RINT1_TIP1 PF04437.13 KIY65897.1 - 1.5e-92 311.1 0.0 3.5e-92 309.9 0.0 1.6 2 0 0 2 2 2 1 RINT-1 / TIP-1 family RNB PF00773.19 KIY65897.1 - 0.011 15.0 2.3 0.27 10.5 2.4 2.2 2 0 0 2 2 2 0 RNB domain Baculo_PEP_C PF04513.12 KIY65897.1 - 0.33 11.0 5.7 3.4 7.7 2.1 3.2 2 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Pro_CA PF00484.19 KIY65898.1 - 1.3e-12 48.3 0.0 1.6e-12 47.9 0.0 1.2 1 0 0 1 1 1 1 Carbonic anhydrase Lactamase_B_2 PF12706.7 KIY65899.1 - 7.6e-24 84.3 0.0 1.1e-16 61.0 0.0 2.2 1 1 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KIY65899.1 - 5.1e-05 23.4 0.2 0.0017 18.4 0.0 2.3 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily DeoRC PF00455.22 KIY65899.1 - 0.18 11.7 0.1 0.44 10.5 0.0 1.6 2 0 0 2 2 2 0 DeoR C terminal sensor domain PRELI PF04707.14 KIY65900.1 - 3.9e-34 117.7 0.0 4.9e-34 117.4 0.0 1.1 1 0 0 1 1 1 1 PRELI-like family Bac_DnaA PF00308.18 KIY65900.1 - 0.023 14.5 0.0 0.032 14.1 0.0 1.1 1 0 0 1 1 1 0 Bacterial dnaA protein RIC1 PF07064.13 KIY65901.1 - 1.9e-96 322.4 0.5 2.6e-96 321.9 0.5 1.2 1 0 0 1 1 1 1 RIC1 PD40 PF07676.12 KIY65901.1 - 0.007 16.3 0.6 2.2 8.3 0.2 3.0 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat ANAPC4_WD40 PF12894.7 KIY65901.1 - 0.05 13.9 0.1 3.7 7.9 0.0 3.5 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain BolA PF01722.18 KIY65902.1 - 1.2e-15 57.6 0.0 1.9e-15 56.9 0.0 1.4 1 1 0 1 1 1 1 BolA-like protein RGS PF00615.19 KIY65903.1 - 4.1e-08 33.5 0.0 6.2e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain Pox_A14 PF05767.12 KIY65903.1 - 0.88 9.8 2.7 8.9 6.6 0.4 2.6 1 1 1 2 2 2 0 Poxvirus virion envelope protein A14 OPT PF03169.15 KIY65904.1 - 7.1e-174 579.8 58.2 8.1e-174 579.7 58.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein zinc_ribbon_11 PF11682.8 KIY65905.1 - 0.032 14.3 0.0 0.05 13.6 0.0 1.4 1 0 0 1 1 1 0 Probable zinc-ribbon TauD PF02668.16 KIY65906.1 - 3e-52 178.1 0.3 3.7e-52 177.8 0.3 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DIE2_ALG10 PF04922.12 KIY65907.1 - 5.4e-123 411.2 13.1 6.4e-123 410.9 13.1 1.1 1 0 0 1 1 1 1 DIE2/ALG10 family SAM_decarbox PF01536.16 KIY65910.1 - 1.8e-114 382.5 0.0 2.2e-114 382.2 0.0 1.1 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase APG5 PF04106.12 KIY65911.1 - 5.6e-63 212.6 0.0 1e-62 211.7 0.0 1.4 2 0 0 2 2 2 1 Autophagy protein Apg5 Dfp1_Him1_M PF08630.10 KIY65912.1 - 9.4e-25 87.3 1.2 2e-24 86.2 0.0 2.2 2 0 0 2 2 2 1 Dfp1/Him1, central region zf-DBF PF07535.12 KIY65912.1 - 3.7e-20 71.8 1.2 6.7e-20 70.9 1.2 1.5 1 0 0 1 1 1 1 DBF zinc finger Zn_clus PF00172.18 KIY65913.1 - 2.7e-08 33.8 28.7 0.00023 21.2 13.7 2.4 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain PMP1_2 PF08114.11 KIY65916.1 - 0.069 12.9 0.4 0.14 11.9 0.4 1.5 1 0 0 1 1 1 0 ATPase proteolipid family zf-C2H2_2 PF12756.7 KIY65917.1 - 2.9e-35 120.6 3.3 1.1e-29 102.8 0.3 2.3 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 KIY65917.1 - 1.2e-08 35.0 2.6 1.2e-08 35.0 2.6 2.0 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KIY65917.1 - 3.3e-08 33.6 3.1 3.3e-08 33.6 3.1 2.9 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KIY65917.1 - 0.00025 21.6 6.4 0.087 13.7 0.2 4.0 3 0 0 3 3 3 1 C2H2-type zinc finger BUD22 PF09073.10 KIY65917.1 - 0.00058 19.3 3.8 0.00093 18.7 3.8 1.3 1 0 0 1 1 1 1 BUD22 zf-C2H2 PF00096.26 KIY65917.1 - 0.0015 18.9 10.3 0.062 13.8 0.7 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-DBF PF07535.12 KIY65917.1 - 0.1 12.8 2.3 0.23 11.6 1.1 2.2 2 0 0 2 2 2 0 DBF zinc finger CDC45 PF02724.14 KIY65917.1 - 0.22 9.8 3.4 0.27 9.5 3.4 1.2 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 KIY65917.1 - 1.5 8.6 7.2 0.13 12.0 1.6 1.9 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 HA2 PF04408.23 KIY65918.1 - 1.3e-21 76.9 0.0 1.3e-21 76.9 0.0 4.2 2 1 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KIY65918.1 - 1.6e-18 66.8 0.3 4.3e-18 65.4 0.3 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KIY65918.1 - 2.2e-15 57.0 0.0 5.7e-15 55.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KIY65918.1 - 8.3e-08 32.2 0.1 3.6e-07 30.1 0.0 2.1 2 1 1 3 3 3 1 DEAD/DEAH box helicase AAA_30 PF13604.6 KIY65918.1 - 4.1e-05 23.4 0.1 9.5e-05 22.2 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KIY65918.1 - 0.00077 19.7 0.1 0.0041 17.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KIY65918.1 - 0.0012 19.2 0.1 0.0012 19.2 0.1 2.2 3 0 0 3 3 3 1 AAA domain T2SSE PF00437.20 KIY65918.1 - 0.01 14.9 0.0 0.02 14.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein ResIII PF04851.15 KIY65918.1 - 0.14 12.1 1.7 3.1 7.8 0.0 3.1 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit WD40 PF00400.32 KIY65919.1 - 3.2e-13 49.9 7.3 0.0031 18.3 0.0 5.6 5 1 1 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY65919.1 - 6.7e-07 29.5 0.1 0.066 13.5 0.0 4.0 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain DASH_Spc34 PF08657.10 KIY65920.1 - 0.0026 17.6 1.0 0.3 10.9 0.0 2.2 2 0 0 2 2 2 1 DASH complex subunit Spc34 IMD PF08397.11 KIY65920.1 - 0.0038 16.6 0.6 0.006 16.0 0.6 1.2 1 0 0 1 1 1 1 IRSp53/MIM homology domain Spc7 PF08317.11 KIY65920.1 - 0.0042 16.0 2.0 0.0064 15.4 2.0 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF724 PF05266.14 KIY65920.1 - 0.0072 16.2 1.1 0.012 15.5 1.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF724) Jnk-SapK_ap_N PF09744.9 KIY65920.1 - 0.0081 16.4 2.5 0.015 15.5 2.5 1.4 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 LCD1 PF09798.9 KIY65920.1 - 0.023 13.2 0.7 0.031 12.8 0.7 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein DUF641 PF04859.12 KIY65920.1 - 0.047 14.0 2.2 0.078 13.3 2.2 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Fmp27_WPPW PF10359.9 KIY65920.1 - 0.42 9.4 3.4 0.6 8.9 3.4 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Uso1_p115_C PF04871.13 KIY65920.1 - 1.1 9.6 5.4 2.5 8.5 5.4 1.5 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF2203 PF09969.9 KIY65920.1 - 1.1 9.9 3.7 9.4 7.0 3.1 2.5 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) DOCK_N PF16172.5 KIY65921.1 - 8.7e-115 383.6 0.0 1.2e-114 383.2 0.0 1.2 1 0 0 1 1 1 1 DOCK N-terminus DHR-2 PF06920.13 KIY65921.1 - 6.9e-70 236.2 0.0 1.8e-69 234.8 0.0 1.7 1 1 0 1 1 1 1 Dock homology region 2 DOCK-C2 PF14429.6 KIY65921.1 - 5.8e-48 163.3 0.0 1.8e-47 161.7 0.0 1.9 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins Dynamitin PF04912.14 KIY65924.1 - 1.1e-56 192.9 7.6 1.1e-55 189.6 7.6 2.2 1 1 0 1 1 1 1 Dynamitin TPR_MLP1_2 PF07926.12 KIY65924.1 - 0.0019 18.3 4.9 0.0019 18.3 4.9 2.5 3 0 0 3 3 3 1 TPR/MLP1/MLP2-like protein Baculo_PEP_C PF04513.12 KIY65924.1 - 0.0036 17.4 3.3 0.055 13.5 1.1 3.0 3 1 1 4 4 4 1 Baculovirus polyhedron envelope protein, PEP, C terminus Prefoldin_2 PF01920.20 KIY65924.1 - 0.0048 16.8 1.8 0.39 10.7 1.5 3.2 2 1 0 2 2 2 1 Prefoldin subunit Spc7 PF08317.11 KIY65924.1 - 0.016 14.1 0.5 0.032 13.1 0.5 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein Perilipin PF03036.16 KIY65924.1 - 0.028 13.5 0.5 0.049 12.6 0.5 1.3 1 0 0 1 1 1 0 Perilipin family Fib_alpha PF08702.10 KIY65924.1 - 0.045 13.9 0.0 0.12 12.5 0.1 1.7 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Sigma70_ner PF04546.13 KIY65924.1 - 0.079 12.8 2.3 0.22 11.4 0.2 2.4 2 1 0 2 2 2 0 Sigma-70, non-essential region Tropomyosin_1 PF12718.7 KIY65924.1 - 1.3 9.2 6.8 0.78 9.9 1.9 2.7 3 0 0 3 3 3 0 Tropomyosin like Apolipoprotein PF01442.18 KIY65924.1 - 1.9 8.3 15.3 0.28 11.0 2.5 3.7 5 0 0 5 5 5 0 Apolipoprotein A1/A4/E domain Mito_carr PF00153.27 KIY65925.1 - 2.7e-61 203.5 1.8 4.5e-21 74.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DEAD PF00270.29 KIY65926.1 - 7.3e-34 117.0 0.0 1e-33 116.5 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIY65926.1 - 2.6e-28 98.6 0.0 5.3e-28 97.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIY65926.1 - 0.00031 20.8 0.0 0.00071 19.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CDC45 PF02724.14 KIY65926.1 - 0.0014 17.0 0.6 0.0019 16.6 0.6 1.1 1 0 0 1 1 1 1 CDC45-like protein SWIRM-assoc_2 PF16496.5 KIY65926.1 - 0.039 12.8 4.6 0.06 12.2 4.6 1.2 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal TLP-20 PF06088.11 KIY65926.1 - 0.15 11.9 1.3 0.29 11.0 1.3 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) UPF0239 PF06783.11 KIY65926.1 - 0.8 9.9 6.0 1.8 8.8 6.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0239) Nop14 PF04147.12 KIY65926.1 - 2.9 6.0 11.1 4.9 5.2 11.1 1.3 1 0 0 1 1 1 0 Nop14-like family Clathrin PF00637.20 KIY65927.1 - 1e-19 70.9 0.0 2.2e-14 53.5 0.6 2.6 2 0 0 2 2 2 2 Region in Clathrin and VPS VPS11_C PF12451.8 KIY65927.1 - 4.9e-12 45.9 0.2 4.9e-12 45.9 0.2 2.0 2 0 0 2 2 2 1 Vacuolar protein sorting protein 11 C terminal zf-C3H2C3 PF17122.5 KIY65927.1 - 1.5e-06 28.1 9.0 2.6e-06 27.4 9.0 1.4 1 0 0 1 1 1 1 Zinc-finger zf-C3HC4_2 PF13923.6 KIY65927.1 - 0.0012 18.7 9.3 0.002 17.9 9.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 KIY65927.1 - 0.035 14.0 1.9 0.073 13.0 1.9 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_2 PF13639.6 KIY65927.1 - 0.053 13.9 9.9 0.098 13.0 9.9 1.5 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.6 KIY65927.1 - 0.07 13.1 8.9 0.12 12.4 8.9 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Mut7-C PF01927.16 KIY65927.1 - 0.12 12.4 2.2 0.2 11.8 0.9 2.0 2 0 0 2 2 2 0 Mut7-C RNAse domain zf-rbx1 PF12678.7 KIY65927.1 - 0.25 11.6 7.9 0.55 10.6 7.9 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain TPR_2 PF07719.17 KIY65927.1 - 0.27 11.5 2.5 2.5 8.4 0.1 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-RING_UBOX PF13445.6 KIY65927.1 - 2.7 8.1 8.6 5.5 7.1 8.6 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_11 PF17123.5 KIY65927.1 - 6 6.7 7.3 13 5.6 7.3 1.6 1 0 0 1 1 1 0 RING-like zinc finger zf-C3HC4 PF00097.25 KIY65927.1 - 7.2 6.6 10.1 13 5.7 10.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ATP-synt_J PF04911.12 KIY65928.1 - 3.2e-21 74.6 0.4 4.5e-21 74.2 0.4 1.2 1 0 0 1 1 1 1 ATP synthase j chain GEN1_C PF18380.1 KIY65929.1 - 1.8e-19 70.6 2.2 1.8e-19 70.6 2.2 4.2 3 2 0 3 3 3 1 Holliday junction resolvase Gen1 C-terminal domain XPG_I PF00867.18 KIY65929.1 - 3.2e-17 62.7 0.3 1.2e-16 60.8 0.0 2.1 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.17 KIY65929.1 - 2.2e-07 31.3 1.4 2.5e-07 31.1 0.0 1.9 2 0 0 2 2 2 1 XPG N-terminal domain EVC2_like PF12297.8 KIY65929.1 - 0.87 8.2 5.5 1.4 7.6 5.5 1.2 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein NARP1 PF12569.8 KIY65929.1 - 7.6 5.3 8.9 15 4.3 8.9 1.4 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 CDC73_C PF05179.14 KIY65930.1 - 7.5e-54 181.7 0.9 1.6e-53 180.6 0.9 1.5 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal CDC73_N PF16050.5 KIY65930.1 - 1.9e-08 34.0 0.5 0.0048 16.3 0.0 2.3 1 1 1 2 2 2 2 Paf1 complex subunit CDC73 N-terminal DSPc PF00782.20 KIY65931.1 - 1.3e-25 89.8 0.0 3.1e-25 88.5 0.0 1.7 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DUF4484 PF14831.6 KIY65931.1 - 0.083 12.9 0.6 0.17 11.9 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) Amidohydro_1 PF01979.20 KIY65932.1 - 2.5e-65 221.0 3.2 3.7e-65 220.5 3.2 1.2 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 KIY65932.1 - 1.5e-57 193.1 0.6 3.4e-57 192.0 0.6 1.6 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.20 KIY65932.1 - 2.3e-41 139.8 0.1 6.3e-41 138.4 0.1 1.8 1 0 0 1 1 1 1 Urease beta subunit Urease_gamma PF00547.18 KIY65932.1 - 4.6e-39 132.7 0.6 1.6e-38 131.0 0.2 2.1 2 0 0 2 2 2 1 Urease, gamma subunit Amidohydro_3 PF07969.11 KIY65932.1 - 0.00037 20.1 0.5 0.0015 18.0 0.1 2.2 2 0 0 2 2 2 1 Amidohydrolase family Peptidase_M17 PF00883.21 KIY65934.1 - 2.9e-120 401.2 0.1 3.7e-120 400.9 0.1 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 KIY65934.1 - 1e-05 25.4 0.0 2.2e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain bZIP_2 PF07716.15 KIY65935.1 - 8.6e-07 28.9 9.1 1.4e-06 28.3 9.1 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KIY65935.1 - 1.3e-05 25.2 8.2 2e-05 24.6 8.2 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 KIY65935.1 - 0.0074 16.8 2.8 0.0099 16.4 2.8 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor Herpes_DNAp_acc PF04929.12 KIY65935.1 - 0.94 8.4 6.0 1.1 8.2 6.0 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor R2K_3 PF14243.6 KIY65936.1 - 0.016 15.2 0.5 0.036 14.1 0.5 1.6 1 0 0 1 1 1 0 ATP-grasp domain, R2K clade family 3 DUF3662 PF12401.8 KIY65936.1 - 0.066 13.6 0.3 2.9 8.3 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2662) DUF5068 PF16781.5 KIY65936.1 - 0.15 11.8 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5068) TTL PF03133.15 KIY65936.1 - 0.16 11.1 0.2 0.36 9.9 0.0 1.6 2 0 0 2 2 2 0 Tubulin-tyrosine ligase family TP_methylase PF00590.20 KIY65937.1 - 1.4e-41 142.8 0.5 1.4e-41 142.8 0.5 1.7 2 0 0 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.6 KIY65937.1 - 7.6e-14 52.0 0.0 1.9e-13 50.7 0.0 1.7 1 1 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 KIY65937.1 - 1.2e-11 44.0 0.0 2.1e-07 30.4 0.0 2.4 2 0 0 2 2 2 2 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 KIY65937.1 - 1.5e-09 37.1 0.1 3.5e-09 35.9 0.1 1.7 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central SRP14 PF02290.15 KIY65938.1 - 6.2e-19 68.2 0.1 6.2e-19 68.2 0.1 1.9 2 1 0 2 2 2 1 Signal recognition particle 14kD protein MARVEL PF01284.23 KIY65939.1 - 5.5e-12 45.9 14.0 6.4e-12 45.7 14.0 1.1 1 0 0 1 1 1 1 Membrane-associating domain ABC2_membrane_3 PF12698.7 KIY65939.1 - 0.13 11.4 11.5 0.21 10.7 11.5 1.3 1 1 0 1 1 1 0 ABC-2 family transporter protein Malic_M PF03949.15 KIY65940.1 - 1.6e-86 289.8 0.0 2.2e-86 289.3 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 KIY65940.1 - 2e-60 203.7 0.0 3.1e-60 203.1 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain F-box PF00646.33 KIY65941.1 - 0.37 10.7 2.1 1.5 8.8 0.2 3.0 3 0 0 3 3 3 0 F-box domain F-box-like PF12937.7 KIY65943.1 - 1.9e-07 30.9 3.6 1.9e-07 30.9 3.6 2.5 2 0 0 2 2 2 1 F-box-like Pec_lyase_C PF00544.19 KIY65944.1 - 5.1e-36 124.2 10.6 6.9e-36 123.8 10.6 1.2 1 0 0 1 1 1 1 Pectate lyase DLH PF01738.18 KIY65945.1 - 2.7e-20 72.9 0.0 3.1e-20 72.6 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_C14 PF00656.22 KIY65948.1 - 5e-19 69.2 0.0 9.1e-19 68.4 0.0 1.3 1 0 0 1 1 1 1 Caspase domain Lactamase_B_2 PF12706.7 KIY65949.1 - 1.1e-12 47.9 1.4 2.6e-12 46.7 1.4 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KIY65949.1 - 7.6e-06 26.1 0.0 1.6e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily PDEase_II PF02112.15 KIY65949.1 - 0.018 14.1 0.0 0.029 13.5 0.0 1.2 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II Enolase_C PF00113.22 KIY65950.1 - 1.2e-144 481.0 0.1 1.6e-144 480.6 0.1 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 KIY65950.1 - 6.4e-59 197.8 0.1 1.1e-58 197.1 0.1 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 KIY65950.1 - 3.8e-08 33.2 0.0 7.1e-08 32.3 0.0 1.4 1 1 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 KIY65950.1 - 0.0018 17.5 0.1 0.0045 16.2 0.1 1.6 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus Cu_amine_oxid PF01179.20 KIY65952.1 - 1.1e-156 521.9 0.0 1.3e-156 521.6 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 KIY65952.1 - 5.5e-17 62.0 0.0 1.3e-16 60.8 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 KIY65952.1 - 1.3e-05 25.3 0.0 2.8e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain CorA PF01544.18 KIY65953.1 - 5.4e-30 104.7 4.8 5.5e-27 94.8 1.9 2.4 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein DUF5360 PF17314.2 KIY65953.1 - 0.074 13.1 2.3 0.14 12.2 1.8 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF5360) Abhydrolase_1 PF00561.20 KIY65954.1 - 8e-14 51.9 0.5 7.3e-10 38.9 0.3 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIY65954.1 - 6.3e-12 46.6 2.0 9.2e-12 46.0 2.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIY65954.1 - 7.5e-09 35.2 0.1 1.5e-07 31.0 0.1 2.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 FSH1 PF03959.13 KIY65954.1 - 0.034 13.8 0.0 0.17 11.5 0.0 2.0 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Dus PF01207.17 KIY65955.1 - 2.9e-51 174.4 0.0 4.5e-51 173.8 0.0 1.3 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Shisa PF13908.6 KIY65956.1 - 0.00067 20.0 0.1 0.001 19.3 0.1 1.2 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator DUF3894 PF13033.6 KIY65956.1 - 0.028 14.5 0.5 0.048 13.8 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3894) Orf78 PF06024.12 KIY65956.1 - 0.066 13.5 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 Orf78 (ac78) CD225 PF04505.12 KIY65956.1 - 0.086 13.0 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Interferon-induced transmembrane protein TRIQK PF15168.6 KIY65956.1 - 0.19 11.7 1.0 0.47 10.4 0.5 1.8 2 0 0 2 2 2 0 Triple QxxK/R motif-containing protein family Abhydrolase_1 PF00561.20 KIY65957.1 - 4.3e-14 52.8 0.0 1.8e-13 50.7 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIY65957.1 - 1.4e-12 48.7 0.0 2e-12 48.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIY65957.1 - 2.3e-08 33.6 0.0 7e-05 22.2 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Pkinase PF00069.25 KIY65960.1 - 1.2e-71 241.2 0.0 1.7e-71 240.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY65960.1 - 7.8e-52 176.1 0.0 1.1e-51 175.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIY65960.1 - 1.8e-05 23.7 0.0 3.5e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KIY65960.1 - 0.00015 21.2 0.0 0.0018 17.7 0.0 2.2 2 0 0 2 2 2 1 Kinase-like DUF1241 PF06840.11 KIY65960.1 - 0.0013 18.4 0.1 0.0024 17.5 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1241) Haspin_kinase PF12330.8 KIY65960.1 - 0.0037 16.3 0.0 0.26 10.2 0.0 2.1 2 0 0 2 2 2 2 Haspin like kinase domain APH PF01636.23 KIY65961.1 - 9.6e-16 58.4 0.2 1.4e-15 57.9 0.2 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KIY65961.1 - 0.011 15.4 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase HMGL-like PF00682.19 KIY65962.1 - 7.4e-79 265.0 0.3 1.1e-78 264.5 0.3 1.2 1 0 0 1 1 1 1 HMGL-like Glyco_hydro_18 PF00704.28 KIY65964.1 - 1.3e-21 77.7 5.5 5e-21 75.7 5.6 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 CBFD_NFYB_HMF PF00808.23 KIY65965.1 - 2.2e-26 91.9 0.2 3e-26 91.5 0.2 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KIY65965.1 - 1.7e-05 25.2 0.0 2.3e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KIY65965.1 - 0.0031 17.6 0.0 0.0039 17.3 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID-18kDa PF02269.16 KIY65965.1 - 0.0037 17.2 0.0 0.0053 16.8 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.13 KIY65965.1 - 0.014 15.4 0.0 0.022 14.7 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated TFIID_20kDa PF03847.13 KIY65965.1 - 0.03 14.8 0.0 0.071 13.6 0.0 1.6 2 0 0 2 2 2 0 Transcription initiation factor TFIID subunit A CENP-X PF09415.10 KIY65965.1 - 0.047 14.0 0.1 0.072 13.4 0.1 1.4 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Calreticulin PF00262.18 KIY65966.1 - 1.2e-158 527.8 7.8 1.8e-158 527.2 7.8 1.3 1 0 0 1 1 1 1 Calreticulin family GTP_EFTU PF00009.27 KIY65966.1 - 2.3e-43 148.0 0.0 3.7e-43 147.3 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 KIY65966.1 - 1.9e-37 128.6 1.8 4.5e-37 127.3 1.8 1.7 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 KIY65966.1 - 5.4e-24 84.3 0.0 1.3e-23 83.1 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 KIY65966.1 - 9.1e-22 76.9 0.0 2e-21 75.8 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KIY65966.1 - 1.6e-09 38.0 0.0 3.6e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 KIY65966.1 - 1.1e-06 28.7 0.5 4.8e-05 23.4 0.0 3.4 4 0 0 4 4 4 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 KIY65966.1 - 1.2e-05 25.3 0.1 3.1e-05 24.0 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KIY65966.1 - 0.015 14.7 0.0 0.038 13.4 0.0 1.6 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Prefoldin_2 PF01920.20 KIY65967.1 - 1.2e-18 67.0 8.5 1.5e-18 66.6 8.5 1.1 1 0 0 1 1 1 1 Prefoldin subunit Mei5 PF10376.9 KIY65967.1 - 0.0053 16.6 2.8 0.0077 16.1 2.8 1.2 1 0 0 1 1 1 1 Double-strand recombination repair protein Tropomyosin_1 PF12718.7 KIY65967.1 - 0.01 16.0 0.6 0.01 16.0 0.6 2.0 2 0 0 2 2 2 0 Tropomyosin like BPS1 PF05633.11 KIY65967.1 - 0.077 12.0 2.4 0.088 11.8 2.4 1.0 1 0 0 1 1 1 0 Protein BYPASS1-related LPP PF04728.13 KIY65967.1 - 0.099 13.0 0.4 0.099 13.0 0.4 2.1 2 1 0 2 2 2 0 Lipoprotein leucine-zipper FliD_C PF07195.12 KIY65967.1 - 0.12 11.8 5.5 0.43 10.0 0.7 2.0 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Cep57_MT_bd PF06657.13 KIY65967.1 - 0.25 11.8 8.2 2.8 8.5 0.5 2.2 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Spc24 PF08286.11 KIY65967.1 - 0.65 10.3 6.1 0.4 10.9 1.2 2.0 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Ax_dynein_light PF10211.9 KIY65967.1 - 2.7 7.9 10.5 0.36 10.7 2.3 2.0 1 1 1 2 2 2 0 Axonemal dynein light chain SGL PF08450.12 KIY65969.1 - 1.8e-05 24.5 0.1 2.8e-05 23.8 0.1 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region SGL PF08450.12 KIY65970.1 - 5.7e-05 22.8 0.0 8.4e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region SGL PF08450.12 KIY65971.1 - 0.0015 18.2 0.0 0.0024 17.5 0.0 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 KIY65971.1 - 0.0048 17.1 0.5 0.019 15.1 0.0 2.4 3 0 0 3 3 3 1 Arylesterase Dimer_Tnp_hAT PF05699.14 KIY65974.1 - 4.3e-07 29.6 0.0 4.7e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF2180 PF09947.9 KIY65975.1 - 0.041 13.9 0.2 0.083 12.9 0.2 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2180) CBM60 PF16841.5 KIY65975.1 - 0.056 13.9 0.1 0.12 12.9 0.1 1.5 1 0 0 1 1 1 0 Ca-dependent carbohydrate-binding module xylan-binding Mac PF12464.8 KIY65975.1 - 0.11 12.7 2.0 0.31 11.3 2.0 1.7 1 0 0 1 1 1 0 Maltose acetyltransferase zf-FLZ PF04570.14 KIY65975.1 - 0.17 11.4 5.1 0.19 11.2 0.4 2.5 1 1 1 2 2 2 0 zinc-finger of the FCS-type, C2-C2 Cag12 PF13117.6 KIY65976.1 - 0.12 12.9 0.0 0.39 11.3 0.0 1.9 1 0 0 1 1 1 0 Cag pathogenicity island protein Cag12 MMM1 PF10296.9 KIY65977.1 - 6.7e-08 31.9 0.0 2.7e-07 30.0 0.0 1.8 1 1 1 2 2 2 1 Maintenance of mitochondrial morphology protein 1 PH_11 PF15413.6 KIY65977.1 - 0.013 15.9 0.0 0.033 14.6 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain PH PF00169.29 KIY65977.1 - 0.081 13.4 0.0 0.35 11.4 0.0 2.1 1 1 0 1 1 1 0 PH domain PH_9 PF15410.6 KIY65977.1 - 0.12 12.7 0.0 0.3 11.5 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain Rsm22 PF09243.10 KIY65980.1 - 7.3e-39 133.7 0.0 2.2e-37 128.9 0.0 3.0 1 1 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 DUF2615 PF11027.8 KIY65981.1 - 0.064 13.4 0.0 0.067 13.3 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) dsrm PF00035.26 KIY65982.1 - 1.5e-06 28.8 0.0 1.7e-06 28.6 0.0 1.1 1 0 0 1 1 1 1 Double-stranded RNA binding motif eIF_4G1 PF12152.8 KIY65982.1 - 0.11 12.6 0.1 0.17 12.1 0.0 1.4 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4G1 WD40 PF00400.32 KIY65983.1 - 7.3e-40 134.2 20.0 9.8e-08 32.6 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY65983.1 - 3.3e-16 59.4 0.0 0.0032 17.7 0.1 5.5 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIY65983.1 - 0.0036 17.2 0.0 4.1 7.3 0.0 2.6 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KIY65983.1 - 0.014 14.4 0.2 3.9 6.3 0.0 3.5 2 1 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KIY65983.1 - 0.031 13.6 0.0 7.4 5.8 0.0 3.4 2 1 1 3 3 3 0 WD40-like domain PQQ_2 PF13360.6 KIY65983.1 - 0.039 13.5 0.1 1.6 8.2 0.0 2.1 1 1 0 2 2 2 0 PQQ-like domain DUF5012 PF16404.5 KIY65984.1 - 0.023 14.8 0.2 0.041 14.0 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5012) MRC1 PF09444.10 KIY65984.1 - 2.5 8.6 5.0 24 5.4 0.2 2.7 3 0 0 3 3 3 0 MRC1-like domain Macoilin PF09726.9 KIY65985.1 - 5.2e-05 22.0 12.6 6.3e-05 21.8 12.6 1.2 1 0 0 1 1 1 1 Macoilin family Syntaxin_2 PF14523.6 KIY65985.1 - 0.012 16.0 11.4 0.012 16.0 11.4 2.8 2 2 0 2 2 2 0 Syntaxin-like protein HMMR_N PF15905.5 KIY65985.1 - 0.11 12.0 38.1 0.41 10.1 37.7 1.9 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal HTH_WhiA PF02650.14 KIY65985.1 - 0.22 11.9 0.3 0.22 11.9 0.3 2.9 3 0 0 3 3 3 0 WhiA C-terminal HTH domain Rootletin PF15035.6 KIY65985.1 - 2 8.4 36.9 45 4.0 35.9 2.9 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Lebercilin PF15619.6 KIY65985.1 - 2.2 7.9 42.0 1.1 8.9 36.2 2.9 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease ENT PF03735.14 KIY65985.1 - 5 7.3 10.8 0.13 12.3 1.4 2.8 3 0 0 3 3 3 0 ENT domain FUSC PF04632.12 KIY65985.1 - 6.2 5.2 14.0 1.1 7.7 9.8 1.6 1 1 0 1 1 1 0 Fusaric acid resistance protein family DUF948 PF06103.11 KIY65985.1 - 6.5 7.1 22.0 1.4 9.2 2.9 3.8 1 1 3 4 4 4 0 Bacterial protein of unknown function (DUF948) Laminin_II PF06009.12 KIY65985.1 - 8.4 6.4 27.0 9.8 6.2 5.3 3.3 1 1 2 3 3 3 0 Laminin Domain II Tropomyosin PF00261.20 KIY65985.1 - 9.3 5.5 41.3 1.8 7.9 25.9 2.3 1 1 1 2 2 2 0 Tropomyosin MscS_porin PF12795.7 KIY65986.1 - 0.011 15.3 2.2 0.021 14.4 1.0 1.7 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain Pox_A_type_inc PF04508.12 KIY65986.1 - 2.2 8.3 6.5 1.1 9.2 0.4 2.8 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Evr1_Alr PF04777.13 KIY65987.1 - 1.8e-27 95.7 0.1 2.7e-27 95.2 0.1 1.2 1 0 0 1 1 1 1 Erv1 / Alr family Clat_adaptor_s PF01217.20 KIY65988.1 - 7.2e-57 191.3 3.0 7.9e-57 191.2 3.0 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Ribosomal_L1 PF00687.21 KIY65989.1 - 6e-18 65.3 0.0 7.2e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family NTP_transf_8 PF12281.8 KIY65989.1 - 0.051 13.6 0.8 0.098 12.7 0.8 1.4 1 0 0 1 1 1 0 Nucleotidyltransferase F-box-like PF12937.7 KIY65990.1 - 0.0029 17.5 0.7 0.007 16.2 0.7 1.7 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.6 KIY65990.1 - 0.11 12.5 0.2 0.2 11.7 0.2 1.4 1 0 0 1 1 1 0 F-box-like domain CAF1A PF12253.8 KIY65991.1 - 0.053 13.7 0.2 0.13 12.5 0.2 1.6 1 0 0 1 1 1 0 Chromatin assembly factor 1 subunit A Dynamitin PF04912.14 KIY65991.1 - 0.16 11.3 1.0 0.23 10.8 1.0 1.1 1 0 0 1 1 1 0 Dynamitin IPPT PF01715.17 KIY65992.1 - 0.004 17.0 0.0 0.0061 16.4 0.0 1.2 1 0 0 1 1 1 1 IPP transferase 4HBT_3 PF13622.6 KIY65995.1 - 5.2e-14 53.1 0.1 7.7e-14 52.5 0.1 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily Cyclase_polyket PF04673.12 KIY65997.1 - 0.18 12.1 1.0 0.29 11.4 1.0 1.3 1 0 0 1 1 1 0 Polyketide synthesis cyclase Oberon_cc PF16312.5 KIY65997.1 - 0.42 10.5 4.9 1 9.3 4.8 1.7 1 1 1 2 2 2 0 Coiled-coil region of Oberon CBFD_NFYB_HMF PF00808.23 KIY65998.1 - 2.6e-18 66.1 2.6 2.6e-18 66.1 2.6 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KIY65998.1 - 7.6e-14 52.2 0.4 7.6e-14 52.2 0.4 1.4 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.10 KIY65998.1 - 0.023 15.0 0.1 0.045 14.1 0.1 1.5 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Sel1 PF08238.12 KIY65999.1 - 5.2e-10 39.7 26.1 0.0014 19.2 0.8 6.4 7 0 0 7 7 7 4 Sel1 repeat TPR_2 PF07719.17 KIY65999.1 - 0.87 9.9 7.3 1.6 9.1 0.5 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 KIY65999.1 - 1.5 8.8 7.3 1.8 8.5 0.7 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat polyprenyl_synt PF00348.17 KIY66001.1 - 9.7e-64 214.9 0.0 1.1e-63 214.7 0.0 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase Lipase_3 PF01764.25 KIY66002.1 - 9.3e-08 32.0 0.1 2.1e-06 27.6 0.1 2.2 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KIY66002.1 - 0.074 13.6 0.5 0.34 11.5 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase family RRM_1 PF00076.22 KIY66003.1 - 2.9e-18 65.4 0.0 2.5e-11 43.3 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Acetyltransf_3 PF13302.7 KIY66004.1 - 2.3e-06 28.4 0.0 3.1e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain F-box-like PF12937.7 KIY66005.1 - 5.4e-05 23.0 0.0 0.00011 22.0 0.0 1.5 1 0 0 1 1 1 1 F-box-like Lipase_GDSL_2 PF13472.6 KIY66006.1 - 0.00012 22.6 0.0 0.00015 22.3 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KIY66006.1 - 0.00088 19.3 0.0 0.0019 18.2 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Stealth_CR1 PF17101.5 KIY66007.1 - 6.4e-09 35.4 0.1 1.9e-08 33.8 0.1 1.9 1 0 0 1 1 1 1 Stealth protein CR1, conserved region 1 Stealth_CR2 PF11380.8 KIY66007.1 - 8.7e-08 32.3 0.9 0.00092 19.4 0.1 2.7 1 1 1 2 2 2 2 Stealth protein CR2, conserved region 2 Stealth_CR3 PF17102.5 KIY66007.1 - 4.7e-06 26.4 1.9 5.4e-06 26.2 0.1 2.1 2 0 0 2 2 2 1 Stealth protein CR3, conserved region 3 Stealth_CR4 PF17103.5 KIY66007.1 - 0.081 12.8 0.5 0.22 11.4 0.0 1.9 2 0 0 2 2 2 0 Stealth protein CR4, conserved region 4 COesterase PF00135.28 KIY66008.1 - 4.8e-83 279.8 0.0 6e-83 279.4 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KIY66008.1 - 7.8e-06 25.9 2.4 0.001 18.9 0.2 2.7 2 1 1 3 3 3 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KIY66008.1 - 0.038 13.5 0.2 0.067 12.6 0.2 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family IBR PF01485.21 KIY66010.1 - 3.7e-11 43.1 34.6 2.9e-07 30.6 12.9 3.2 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain Pro_isomerase PF00160.21 KIY66011.1 - 5.5e-46 156.7 0.3 6.1e-46 156.6 0.3 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD AA_synth PF06684.11 KIY66012.1 - 0.054 13.0 0.1 0.12 11.9 0.0 1.5 2 0 0 2 2 2 0 Amino acid synthesis Hid1 PF12722.7 KIY66012.1 - 0.89 7.6 16.1 1.4 7.0 16.1 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Presenilin PF01080.17 KIY66012.1 - 1.5 7.5 7.4 2.8 6.6 7.4 1.6 1 0 0 1 1 1 0 Presenilin Abhydrolase_6 PF12697.7 KIY66013.1 - 7.3e-18 66.0 1.4 9.1e-18 65.7 1.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIY66013.1 - 2e-08 33.8 0.1 8.6e-06 25.2 0.1 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Lipase_3 PF01764.25 KIY66013.1 - 0.00064 19.6 0.0 0.001 19.0 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Arrestin_N PF00339.29 KIY66014.1 - 5.3e-06 26.5 0.1 1.2e-05 25.4 0.1 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KIY66014.1 - 0.0054 17.2 0.1 8.5 6.8 0.0 3.1 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain KH_6 PF15985.5 KIY66014.1 - 0.059 13.7 0.1 0.13 12.7 0.1 1.5 1 0 0 1 1 1 0 KH domain Rad60-SLD_2 PF13881.6 KIY66015.1 - 1.5e-14 54.1 0.0 2.1e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KIY66015.1 - 0.001 18.8 0.0 0.0073 16.0 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin family Aldo_ket_red PF00248.21 KIY66016.1 - 2.5e-67 227.2 0.0 3.2e-67 226.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ERCC4 PF02732.15 KIY66017.1 - 0.0031 17.7 0.1 0.011 16.0 0.0 1.9 1 1 0 1 1 1 1 ERCC4 domain Atg14 PF10186.9 KIY66017.1 - 0.014 14.5 7.9 0.021 13.9 7.0 1.7 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Sigma54_CBD PF04963.13 KIY66017.1 - 0.024 14.5 1.0 0.3 10.9 0.3 2.6 3 0 0 3 3 3 0 Sigma-54 factor, core binding domain Peptidase_M16_C PF05193.21 KIY66017.1 - 0.027 14.5 0.1 0.076 13.0 0.1 1.7 2 0 0 2 2 2 0 Peptidase M16 inactive domain DUF3450 PF11932.8 KIY66017.1 - 0.081 12.2 11.1 0.16 11.2 11.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) APG6_N PF17675.1 KIY66017.1 - 0.25 11.8 11.0 0.69 10.4 11.0 1.7 1 0 0 1 1 1 0 Apg6 coiled-coil region RR_TM4-6 PF06459.12 KIY66017.1 - 0.72 9.6 12.2 1.6 8.5 12.2 1.6 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DGCR6 PF07324.11 KIY66017.1 - 1.8 8.1 9.6 3.2 7.3 9.6 1.3 1 0 0 1 1 1 0 DiGeorge syndrome critical region 6 (DGCR6) protein Caprin-1_C PF12287.8 KIY66017.1 - 3.6 7.6 9.0 0.12 12.5 1.1 2.0 2 0 0 2 2 2 0 Cytoplasmic activation/proliferation-associated protein-1 C term Mitoc_mL59 PF18126.1 KIY66017.1 - 3.6 7.9 13.7 9.4 6.6 13.7 1.7 1 0 0 1 1 1 0 Mitochondrial ribosomal protein mL59 Membralin PF09746.9 KIY66017.1 - 6 5.8 5.5 9.6 5.1 5.5 1.2 1 0 0 1 1 1 0 Tumour-associated protein zf-C2H2 PF00096.26 KIY66018.1 - 2.6e-07 30.7 17.1 0.00019 21.7 2.2 4.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KIY66018.1 - 0.00015 22.0 0.7 0.00015 22.0 0.7 2.7 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 KIY66018.1 - 0.00018 21.8 3.5 0.00018 21.8 3.5 2.9 2 0 0 2 2 2 1 Zinc-finger double domain zf-met PF12874.7 KIY66018.1 - 0.00075 19.8 0.8 0.00075 19.8 0.8 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KIY66018.1 - 0.0018 19.0 1.7 0.0018 19.0 1.7 3.9 3 0 0 3 3 3 1 C2H2-type zinc finger FOXP-CC PF16159.5 KIY66018.1 - 0.58 10.8 16.4 0.97 10.1 0.4 3.0 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 KIY66018.1 - 1 9.7 7.0 3 8.2 7.0 1.8 1 0 0 1 1 1 0 C2H2-type zinc ribbon EF-hand_6 PF13405.6 KIY66019.1 - 3.5e-11 42.1 3.9 4.7e-05 23.0 0.2 3.4 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 KIY66019.1 - 1.9e-10 41.1 2.2 3.7e-06 27.3 0.1 2.5 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 KIY66019.1 - 4.8e-07 28.9 5.7 0.022 14.3 0.2 4.1 4 0 0 4 4 4 2 EF hand EF-hand_9 PF14658.6 KIY66019.1 - 0.0005 20.3 0.0 0.38 11.1 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 KIY66019.1 - 0.0081 15.6 0.7 0.28 10.8 0.2 2.6 2 0 0 2 2 2 1 EF hand DUF2666 PF10869.8 KIY66019.1 - 0.12 12.6 0.0 2.3 8.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2666) PI-PLC-X PF00388.19 KIY66020.1 - 0.00012 21.7 0.0 0.00023 20.8 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Kelch_3 PF13415.6 KIY66021.1 - 1.8e-38 130.1 6.1 5.8e-11 42.4 0.4 6.7 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_4 PF13418.6 KIY66021.1 - 1.5e-35 121.0 14.8 4.9e-11 42.5 0.8 6.6 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 KIY66021.1 - 1.6e-32 110.9 5.4 2.4e-05 24.2 0.0 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 KIY66021.1 - 2.6e-32 110.0 7.4 2.9e-09 36.9 0.6 6.6 4 2 2 6 6 6 6 Kelch motif Kelch_1 PF01344.25 KIY66021.1 - 3.4e-29 100.2 4.9 3.3e-10 39.4 0.6 6.5 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.15 KIY66021.1 - 7.7e-25 85.9 3.6 7.1e-06 25.8 0.2 6.7 6 0 0 6 6 6 6 Kelch motif DUF641 PF04859.12 KIY66021.1 - 0.0005 20.4 2.2 0.0005 20.4 2.2 7.7 5 1 2 7 7 7 2 Plant protein of unknown function (DUF641) BLOC1_2 PF10046.9 KIY66021.1 - 0.0089 16.3 0.5 0.0089 16.3 0.5 6.8 5 3 5 10 10 9 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fez1 PF06818.15 KIY66021.1 - 0.013 16.0 2.7 0.013 16.0 2.7 6.2 2 1 3 5 5 2 0 Fez1 TolA_bind_tri PF16331.5 KIY66021.1 - 0.039 14.0 0.3 0.039 14.0 0.3 8.9 7 4 2 10 10 10 0 TolA binding protein trimerisation DASH_Hsk3 PF08227.11 KIY66021.1 - 0.067 13.6 8.7 0.27 11.6 0.5 4.7 3 0 0 3 3 3 0 DASH complex subunit Hsk3 like Rootletin PF15035.6 KIY66021.1 - 10 6.1 83.2 0.014 15.5 8.0 5.7 1 1 4 5 5 4 0 Ciliary rootlet component, centrosome cohesion Pga1 PF10333.9 KIY66023.1 - 0.042 13.7 0.9 0.22 11.4 0.1 2.3 2 1 0 2 2 2 0 GPI-Mannosyltransferase II co-activator zf-C2H2 PF00096.26 KIY66024.1 - 7.8e-11 41.8 11.6 7e-06 26.2 3.2 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIY66024.1 - 1.1e-09 38.3 9.2 0.00026 21.5 2.0 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KIY66024.1 - 5.4e-08 32.9 10.3 2e-05 24.8 0.2 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KIY66024.1 - 9.8e-05 22.5 2.9 0.0031 17.7 0.4 2.2 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KIY66024.1 - 0.00054 20.3 1.3 0.014 15.8 0.3 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type Zn_ribbon_SprT PF17283.2 KIY66024.1 - 0.0021 17.9 5.8 0.015 15.2 1.0 2.2 2 0 0 2 2 2 1 SprT-like zinc ribbon domain zf-C2HC_2 PF13913.6 KIY66024.1 - 0.0044 16.9 6.2 0.081 12.8 0.4 2.7 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.6 KIY66024.1 - 0.0052 16.8 4.6 0.034 14.1 0.6 2.3 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KIY66024.1 - 0.022 15.1 2.3 0.094 13.1 0.4 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-LYAR PF08790.11 KIY66024.1 - 0.041 13.8 1.3 0.18 11.7 0.1 2.3 2 1 0 2 2 2 0 LYAR-type C2HC zinc finger zf-UBP PF02148.19 KIY66024.1 - 0.07 13.5 2.1 4.1 7.8 1.5 2.1 1 1 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein ADK_lid PF05191.14 KIY66024.1 - 0.2 11.7 2.6 0.66 10.0 0.2 2.2 2 0 0 2 2 2 0 Adenylate kinase, active site lid zf-C2H2_11 PF16622.5 KIY66024.1 - 0.32 10.8 6.4 2.5 7.9 1.8 2.2 2 0 0 2 2 2 0 zinc-finger C2H2-type FYDLN_acid PF09538.10 KIY66024.1 - 1.4 9.6 2.8 42 4.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) mono-CXXC PF15626.6 KIY66026.1 - 1.8 9.0 6.7 3.6 8.0 6.7 1.4 1 0 0 1 1 1 0 single CXXC unit GARS_A PF01071.19 KIY66027.1 - 8.9e-81 270.3 0.0 1.3e-80 269.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.15 KIY66027.1 - 2.1e-34 118.2 0.0 8.1e-34 116.3 0.0 2.1 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.22 KIY66027.1 - 3.5e-33 114.9 0.0 8.7e-33 113.7 0.0 1.6 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.16 KIY66027.1 - 6.8e-29 100.0 0.8 1.7e-28 98.7 0.8 1.8 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 KIY66027.1 - 3.4e-15 56.5 0.4 2.5e-14 53.7 0.7 2.3 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain CPSase_L_D2 PF02786.17 KIY66027.1 - 0.00064 19.3 0.0 0.0012 18.4 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.14 KIY66027.1 - 0.01 15.9 0.0 0.026 14.6 0.0 1.7 2 0 0 2 2 2 0 ATP-grasp domain Sugar_tr PF00083.24 KIY66028.1 - 3.2e-47 161.4 4.6 4.2e-47 161.0 4.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY66028.1 - 1e-22 80.6 14.1 2e-14 53.3 0.1 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KIY66028.1 - 0.00064 19.1 0.9 0.0012 18.2 0.3 1.8 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB WD40 PF00400.32 KIY66030.1 - 2.8e-13 50.1 15.9 9.3e-06 26.3 0.1 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 KIY66030.1 - 7.7e-13 48.5 0.0 5.4e-12 45.8 0.0 2.4 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex eIF2A PF08662.11 KIY66030.1 - 2e-05 24.5 0.1 0.0021 17.9 0.0 2.4 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 KIY66030.1 - 0.00057 20.1 0.8 0.19 12.1 0.1 3.0 2 2 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Amidase PF01425.21 KIY66032.1 - 4e-115 385.3 0.0 4.8e-115 385.1 0.0 1.1 1 0 0 1 1 1 1 Amidase DUF3439 PF11921.8 KIY66032.1 - 0.041 13.8 0.0 0.081 12.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Romo1 PF10247.9 KIY66034.1 - 1.8e-22 79.5 8.9 2.2e-22 79.2 8.9 1.1 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Pex2_Pex12 PF04757.14 KIY66035.1 - 8.9e-23 81.1 5.4 8.7e-22 77.8 5.4 2.0 1 1 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 KIY66035.1 - 1.6e-09 37.5 8.1 2.3e-09 37.0 8.1 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIY66035.1 - 3.6e-08 33.6 11.8 5.8e-08 33.0 11.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KIY66035.1 - 1.7e-07 31.0 9.5 2.6e-07 30.4 9.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KIY66035.1 - 2.5e-07 30.4 10.1 3.7e-07 29.9 10.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KIY66035.1 - 4.6e-07 29.6 8.0 7.3e-07 28.9 8.0 1.2 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KIY66035.1 - 1.6e-06 28.0 9.4 2.4e-06 27.4 9.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KIY66035.1 - 7.6e-06 25.9 5.2 1.8e-05 24.6 5.1 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 KIY66035.1 - 3.1e-05 24.1 8.1 6.3e-05 23.2 8.1 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 KIY66035.1 - 0.0069 16.5 9.9 0.013 15.7 9.9 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 KIY66035.1 - 0.012 15.7 3.3 0.023 14.8 3.3 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_10 PF16685.5 KIY66035.1 - 0.45 10.7 6.5 0.79 9.9 6.5 1.3 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_4 PF14570.6 KIY66035.1 - 0.76 9.6 8.9 1.4 8.8 8.9 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain LSM PF01423.22 KIY66036.1 - 8.1e-15 54.3 0.2 1e-14 53.9 0.2 1.3 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 KIY66036.1 - 0.0039 16.8 0.1 0.0067 16.1 0.1 1.4 1 0 0 1 1 1 1 Hfq protein AAA_6 PF12774.7 KIY66037.1 - 4.7e-126 420.2 0.0 6.3e-125 416.5 0.0 2.9 2 1 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KIY66037.1 - 2.2e-115 386.0 10.2 2.2e-115 386.0 10.2 2.7 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 KIY66037.1 - 8.3e-73 244.1 1.0 8.3e-73 244.1 1.0 4.6 5 1 0 5 5 5 1 ATP-binding dynein motor region AAA_8 PF12780.7 KIY66037.1 - 8.8e-66 221.9 0.0 2.4e-65 220.5 0.0 1.8 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 KIY66037.1 - 7.1e-49 166.7 0.0 2.6e-48 164.8 0.0 2.1 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 KIY66037.1 - 2.9e-43 147.5 0.0 5.7e-36 123.7 0.0 4.8 4 0 0 4 4 4 2 P-loop containing dynein motor region MT PF12777.7 KIY66037.1 - 1.4e-40 139.4 7.0 2.5e-40 138.6 7.0 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 KIY66037.1 - 1.1e-36 126.1 0.0 2.2e-36 125.2 0.0 1.5 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 KIY66037.1 - 2.2e-29 102.0 0.0 4.4e-28 97.8 0.0 2.8 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 KIY66037.1 - 1.3e-27 96.5 0.0 3.8e-12 46.4 0.0 6.1 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 KIY66037.1 - 3.7e-18 65.8 0.2 2.5e-17 63.2 0.0 2.6 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA PF00004.29 KIY66037.1 - 5.1e-13 49.6 0.0 0.0057 17.1 0.0 5.0 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KIY66037.1 - 2.7e-12 47.1 0.0 0.022 15.0 0.0 5.4 4 0 0 4 4 4 2 AAA domain AAA_33 PF13671.6 KIY66037.1 - 7.4e-11 42.4 0.4 0.15 12.2 0.0 5.9 6 0 0 6 6 6 3 AAA domain AAA_16 PF13191.6 KIY66037.1 - 1.6e-08 35.1 0.0 0.67 10.3 0.0 6.2 5 0 0 5 5 5 1 AAA ATPase domain AAA_18 PF13238.6 KIY66037.1 - 2.2e-08 34.7 0.0 0.086 13.4 0.0 5.3 4 0 0 4 4 4 2 AAA domain T2SSE PF00437.20 KIY66037.1 - 5.5e-06 25.6 0.0 0.024 13.7 0.0 3.5 3 0 0 3 3 3 1 Type II/IV secretion system protein Mg_chelatase PF01078.21 KIY66037.1 - 1.1e-05 24.9 1.1 0.51 9.7 0.0 3.6 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI FtsK_SpoIIIE PF01580.18 KIY66037.1 - 0.00011 21.6 0.0 0.28 10.5 0.0 3.7 3 0 0 3 3 3 1 FtsK/SpoIIIE family AAA_30 PF13604.6 KIY66037.1 - 0.00015 21.6 0.3 13 5.5 0.0 4.5 4 0 0 4 4 4 0 AAA domain AAA_lid_1 PF17857.1 KIY66037.1 - 0.0002 21.5 0.8 0.0014 18.8 0.0 2.8 2 0 0 2 2 2 1 AAA+ lid domain AAA_14 PF13173.6 KIY66037.1 - 0.00023 21.2 0.0 1.6 8.8 0.0 4.6 4 0 0 4 4 4 1 AAA domain AAA_19 PF13245.6 KIY66037.1 - 0.00027 21.3 4.4 0.43 10.9 0.0 5.2 5 0 0 5 5 5 1 AAA domain IstB_IS21 PF01695.17 KIY66037.1 - 0.00036 20.3 0.6 0.73 9.5 0.0 4.3 4 0 0 4 4 4 1 IstB-like ATP binding protein Rad17 PF03215.15 KIY66037.1 - 0.0004 20.4 0.1 25 4.7 0.0 5.4 5 0 0 5 5 5 0 Rad17 P-loop domain RNA_helicase PF00910.22 KIY66037.1 - 0.0013 19.1 0.0 10 6.6 0.0 4.5 4 0 0 4 4 4 0 RNA helicase AAA_29 PF13555.6 KIY66037.1 - 0.0013 18.4 0.1 0.85 9.4 0.0 3.5 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_24 PF13479.6 KIY66037.1 - 0.0022 17.7 0.1 34 4.1 0.0 4.9 4 0 0 4 4 4 0 AAA domain ABC_tran PF00005.27 KIY66037.1 - 0.0025 18.4 0.3 12 6.4 0.0 4.5 4 0 0 4 4 3 0 ABC transporter AAA_25 PF13481.6 KIY66037.1 - 0.0085 15.7 0.0 0.59 9.7 0.0 3.7 3 0 0 3 3 3 1 AAA domain AAA_21 PF13304.6 KIY66037.1 - 0.0087 15.9 0.2 5.8 6.6 0.0 3.0 3 0 0 3 3 2 0 AAA domain, putative AbiEii toxin, Type IV TA system RuvB_N PF05496.12 KIY66037.1 - 0.061 13.1 0.1 3.6 7.3 0.0 3.2 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 KIY66037.1 - 0.07 13.1 0.7 16 5.5 0.0 3.9 4 0 0 4 4 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 KIY66037.1 - 0.074 13.0 1.5 39 4.1 0.1 4.6 5 0 0 5 5 4 0 NACHT domain PduV-EutP PF10662.9 KIY66037.1 - 0.11 12.2 0.3 12 5.7 0.1 3.4 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation SRP54 PF00448.22 KIY66037.1 - 0.16 11.6 2.1 42 3.7 0.1 3.8 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain GHMP_kinases_N PF00288.26 KIY66038.1 - 1.7e-10 41.0 0.0 3.4e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KIY66038.1 - 0.011 16.1 0.0 0.032 14.6 0.0 1.8 1 1 0 1 1 1 0 GHMP kinases C terminal S1 PF00575.23 KIY66039.1 - 8.7e-56 186.2 30.9 9.4e-12 45.1 0.2 10.6 10 0 0 10 10 10 9 S1 RNA binding domain TPR_19 PF14559.6 KIY66039.1 - 5.2e-06 26.9 0.2 0.21 12.1 0.0 3.2 2 1 2 4 4 4 2 Tetratricopeptide repeat Suf PF05843.14 KIY66039.1 - 8.7e-05 22.6 0.2 8.7e-05 22.6 0.2 4.1 2 1 2 4 4 4 2 Suppressor of forked protein (Suf) NRDE-2 PF08424.10 KIY66039.1 - 0.00015 21.0 3.7 0.3 10.2 0.5 3.5 1 1 1 3 3 3 2 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 KIY66039.1 - 0.00062 20.4 0.6 21 6.3 0.1 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat S1_2 PF13509.6 KIY66039.1 - 0.00098 19.1 5.3 4.6 7.4 0.0 6.7 7 0 0 7 7 7 1 S1 domain PCB_OB PF17092.5 KIY66039.1 - 0.0046 17.7 3.8 6.8 7.5 0.1 5.3 4 2 0 5 5 5 1 Penicillin-binding protein OB-like domain TPR_21 PF09976.9 KIY66039.1 - 0.013 15.2 0.8 0.033 13.9 0.8 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain TPR_16 PF13432.6 KIY66039.1 - 0.018 15.6 0.0 9.9 6.9 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 KIY66039.1 - 0.12 12.9 0.0 6.8 7.3 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TRAM PF01938.20 KIY66039.1 - 0.2 11.7 7.5 4.3 7.4 0.0 4.2 4 1 1 5 5 5 0 TRAM domain ProQ_C PF17516.2 KIY66039.1 - 1.9 8.0 5.2 4.4 6.8 0.1 4.0 4 0 0 4 4 4 0 ProQ C-terminal domain DUF2470 PF10615.9 KIY66041.1 - 4.9e-16 59.1 0.0 7.5e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) DUF4499 PF14934.6 KIY66041.1 - 1.6e-08 34.8 0.3 2.6e-08 34.1 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4499) Rib PF08428.10 KIY66041.1 - 0.071 13.1 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Rib/alpha-like repeat Sugar_tr PF00083.24 KIY66042.1 - 3.4e-86 289.9 21.5 4e-86 289.7 21.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY66042.1 - 3.2e-27 95.4 28.8 3.2e-27 95.4 28.8 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 KIY66042.1 - 0.33 9.2 14.1 0.55 8.4 6.4 2.9 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family F-box-like PF12937.7 KIY66044.1 - 3.1e-07 30.2 2.5 8.4e-07 28.8 2.5 1.7 1 1 0 1 1 1 1 F-box-like F-box-like_2 PF13013.6 KIY66044.1 - 0.017 15.1 0.5 0.035 14.1 0.3 1.5 1 1 0 1 1 1 0 F-box-like domain F-box PF00646.33 KIY66044.1 - 0.017 15.0 3.4 1.2 9.1 0.5 2.3 2 0 0 2 2 2 0 F-box domain PEP-utilisers_N PF05524.13 KIY66044.1 - 0.085 13.0 0.1 0.1 12.8 0.1 1.2 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal Med9 PF07544.13 KIY66044.1 - 0.092 12.9 0.1 0.12 12.5 0.1 1.2 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 DUF4618 PF15397.6 KIY66044.1 - 0.12 11.8 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) Tektin PF03148.14 KIY66044.1 - 0.15 10.8 0.1 0.16 10.7 0.1 1.1 1 0 0 1 1 1 0 Tektin family BORCS8 PF10167.9 KIY66044.1 - 0.16 11.9 0.0 0.2 11.6 0.0 1.1 1 0 0 1 1 1 0 BLOC-1-related complex sub-unit 8 SKA1 PF07160.12 KIY66044.1 - 0.18 11.6 0.0 0.21 11.4 0.0 1.1 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 AIP3 PF03915.13 KIY66045.1 - 0.0022 17.1 2.0 0.0028 16.8 0.7 1.7 1 1 1 2 2 2 2 Actin interacting protein 3 Syntaxin-6_N PF09177.11 KIY66045.1 - 0.0024 18.4 2.7 0.012 16.2 0.1 2.6 3 0 0 3 3 3 1 Syntaxin 6, N-terminal DUF2207 PF09972.9 KIY66045.1 - 0.0064 15.3 0.5 0.012 14.5 0.0 1.7 2 0 0 2 2 2 1 Predicted membrane protein (DUF2207) PHM7_cyt PF14703.6 KIY66045.1 - 0.014 15.7 0.4 0.17 12.1 0.0 2.3 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter FapA PF03961.13 KIY66045.1 - 0.024 13.3 0.3 0.12 11.0 0.0 2.0 2 0 0 2 2 2 0 Flagellar Assembly Protein A DUF601 PF04642.12 KIY66045.1 - 0.024 14.1 0.4 0.054 13.0 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF601 DivIC PF04977.15 KIY66045.1 - 0.042 13.6 2.4 6 6.7 0.2 3.0 3 0 0 3 3 3 0 Septum formation initiator Suppressor_APC PF11414.8 KIY66045.1 - 0.043 13.9 0.4 12 6.0 0.0 2.4 2 0 0 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein ETRAMP PF09716.10 KIY66045.1 - 0.05 13.7 0.0 0.14 12.2 0.0 2.0 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF5063 PF16702.5 KIY66045.1 - 0.063 13.7 0.1 9.3 6.6 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5063) CHDCT2 PF08074.11 KIY66045.1 - 0.1 12.8 0.6 0.46 10.6 0.2 2.1 2 0 0 2 2 2 0 CHDCT2 (NUC038) domain AAA_13 PF13166.6 KIY66045.1 - 0.11 11.1 6.9 0.069 11.8 2.7 2.2 1 1 0 2 2 2 0 AAA domain MCU PF04678.13 KIY66045.1 - 0.12 12.5 0.3 2.7 8.1 0.0 2.8 3 0 0 3 3 3 0 Mitochondrial calcium uniporter ABC_tran_Xtn PF12848.7 KIY66045.1 - 0.14 12.2 0.0 0.14 12.2 0.0 3.4 4 0 0 4 4 4 0 ABC transporter FliJ PF02050.16 KIY66045.1 - 0.14 12.4 6.6 1.9 8.7 0.2 3.4 4 0 0 4 4 4 0 Flagellar FliJ protein DUF5082 PF16888.5 KIY66045.1 - 0.27 11.5 0.1 0.27 11.5 0.1 2.7 4 0 0 4 4 3 0 Domain of unknown function (DUF5082) PLU-1 PF08429.11 KIY66045.1 - 0.32 10.1 5.1 0.32 10.1 0.2 2.4 3 0 0 3 3 3 0 PLU-1-like protein DUF641 PF04859.12 KIY66045.1 - 0.45 10.8 5.4 0.26 11.6 0.2 2.7 3 0 0 3 3 3 0 Plant protein of unknown function (DUF641) TcdA_TcdB_pore PF12920.7 KIY66045.1 - 0.46 8.7 4.7 0.66 8.1 4.5 1.4 1 1 0 1 1 1 0 TcdA/TcdB pore forming domain DUF3091 PF11291.8 KIY66045.1 - 0.57 10.4 5.2 0.53 10.5 0.4 3.1 2 2 1 3 3 3 0 Protein of unknown function (DUF3091) BLOC1_2 PF10046.9 KIY66045.1 - 2 8.8 6.8 3.5 8.0 0.1 3.6 3 1 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fzo_mitofusin PF04799.13 KIY66045.1 - 4.2 6.9 5.7 1.8 8.1 0.4 2.8 3 1 1 4 4 4 0 fzo-like conserved region SpoIIIAH PF12685.7 KIY66046.1 - 0.0018 18.1 6.6 0.0022 17.8 6.6 1.1 1 0 0 1 1 1 1 SpoIIIAH-like protein CorA PF01544.18 KIY66046.1 - 0.0051 16.2 0.6 0.0068 15.8 0.6 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Zip PF02535.22 KIY66046.1 - 0.049 12.9 4.7 0.058 12.6 4.7 1.3 1 1 0 1 1 1 0 ZIP Zinc transporter FlaC_arch PF05377.11 KIY66046.1 - 0.051 14.0 0.7 1.1 9.8 0.0 2.2 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DNA_pol_phi PF04931.13 KIY66046.1 - 3.9 5.5 20.7 5.1 5.1 20.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi Presenilin PF01080.17 KIY66046.1 - 4.1 6.1 5.3 4.9 5.8 5.3 1.1 1 0 0 1 1 1 0 Presenilin F-box-like PF12937.7 KIY66048.1 - 9.3e-09 35.1 3.7 1.8e-08 34.1 0.0 2.8 3 0 0 3 3 3 1 F-box-like F-box_5 PF18511.1 KIY66048.1 - 0.001 18.6 0.1 0.0028 17.2 0.1 1.8 1 1 0 1 1 1 1 F-box F-box PF00646.33 KIY66048.1 - 0.011 15.6 0.2 0.12 12.2 0.2 2.7 1 1 0 1 1 1 0 F-box domain LRR_8 PF13855.6 KIY66049.1 - 0.026 14.3 0.9 2.6 7.9 0.0 3.1 2 1 0 3 3 3 0 Leucine rich repeat LRR_4 PF12799.7 KIY66049.1 - 0.23 12.0 1.6 20 5.8 0.0 3.3 2 1 0 2 2 2 0 Leucine Rich repeats (2 copies) PI-PLC-X PF00388.19 KIY66050.1 - 1.2e-07 31.4 0.0 1.7e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain F-box-like PF12937.7 KIY66051.1 - 3.7e-09 36.3 0.5 1.1e-08 34.9 0.1 2.1 2 0 0 2 2 2 1 F-box-like F-box_5 PF18511.1 KIY66051.1 - 0.0011 18.5 0.0 0.0025 17.3 0.0 1.6 1 0 0 1 1 1 1 F-box F-box PF00646.33 KIY66051.1 - 0.0016 18.2 0.6 0.023 14.6 0.1 3.0 2 1 0 2 2 2 1 F-box domain Choline_kin_N PF04428.14 KIY66051.1 - 0.024 14.3 0.1 3.2 7.5 0.0 3.0 2 0 0 2 2 2 0 Choline kinase N terminus AbiEi_4 PF13338.6 KIY66051.1 - 0.45 10.7 1.9 22 5.3 0.4 2.6 2 1 0 2 2 2 0 Transcriptional regulator, AbiEi antitoxin UDG PF03167.19 KIY66052.1 - 5.6e-21 75.1 0.0 8e-21 74.6 0.0 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily NuiA PF07924.11 KIY66052.1 - 0.16 12.4 0.0 0.24 11.8 0.0 1.3 1 0 0 1 1 1 0 Nuclease A inhibitor-like protein F-box-like PF12937.7 KIY66053.1 - 2.6e-07 30.4 0.3 8.4e-07 28.8 0.1 2.0 2 0 0 2 2 2 1 F-box-like F-box_5 PF18511.1 KIY66053.1 - 0.0014 18.1 0.2 0.0035 16.9 0.2 1.6 1 0 0 1 1 1 1 F-box F-box PF00646.33 KIY66053.1 - 0.0093 15.8 0.8 0.2 11.6 0.0 3.3 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.7 KIY66054.1 - 2.8e-07 30.3 0.1 9.6e-07 28.6 0.1 2.0 1 0 0 1 1 1 1 F-box-like F-box_5 PF18511.1 KIY66054.1 - 0.00059 19.4 0.3 0.0031 17.1 0.0 2.3 3 0 0 3 3 3 1 F-box F-box PF00646.33 KIY66054.1 - 0.023 14.6 0.2 0.13 12.2 0.2 2.5 1 1 0 1 1 1 0 F-box domain zf-C3HC4_2 PF13923.6 KIY66055.1 - 7.8e-12 44.8 8.5 7.8e-12 44.8 8.5 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIY66055.1 - 3e-09 36.6 8.9 3e-09 36.6 8.9 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KIY66055.1 - 9e-09 35.1 12.0 4.4e-08 32.8 7.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) SAP PF02037.27 KIY66055.1 - 1.2e-08 34.5 0.1 2.4e-08 33.5 0.1 1.5 1 0 0 1 1 1 1 SAP domain zf-C3HC4_4 PF15227.6 KIY66055.1 - 1.7e-08 34.5 9.2 1.7e-08 34.5 9.2 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 KIY66055.1 - 2.4e-08 33.8 9.7 2.4e-08 33.8 9.7 1.9 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 KIY66055.1 - 8.8e-08 32.4 8.8 8.8e-08 32.4 8.8 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 KIY66055.1 - 8.9e-08 32.0 9.7 8.9e-08 32.0 9.7 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_6 PF14835.6 KIY66055.1 - 4e-07 29.8 5.3 2e-05 24.4 2.5 2.3 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 KIY66055.1 - 3.7e-05 23.8 5.7 8.9e-05 22.6 5.7 1.6 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-rbx1 PF12678.7 KIY66055.1 - 6.1e-05 23.2 12.6 0.00013 22.1 7.4 3.1 2 1 0 2 2 2 1 RING-H2 zinc finger domain U-box PF04564.15 KIY66055.1 - 0.00015 21.9 0.0 0.009 16.2 0.0 2.9 3 0 0 3 3 3 1 U-box domain zf-RING_4 PF14570.6 KIY66055.1 - 0.0022 17.7 4.0 0.0022 17.7 4.0 2.9 3 0 0 3 3 3 1 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 KIY66055.1 - 0.01 15.7 14.0 0.019 14.8 8.6 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Rtf2 PF04641.12 KIY66055.1 - 0.029 13.7 8.0 0.12 11.7 8.0 2.1 1 1 0 1 1 1 0 Rtf2 RING-finger zf-Nse PF11789.8 KIY66055.1 - 0.032 14.0 3.4 0.032 14.0 3.4 1.8 2 0 0 2 2 1 0 Zinc-finger of the MIZ type in Nse subunit zf-Di19 PF05605.12 KIY66055.1 - 0.58 10.5 4.1 8 6.9 0.2 3.3 4 0 0 4 4 3 0 Drought induced 19 protein (Di19), zinc-binding zf-P11 PF03854.14 KIY66055.1 - 1.1 9.0 10.8 7.1 6.4 5.8 3.2 2 1 0 2 2 2 0 P-11 zinc finger zf-ANAPC11 PF12861.7 KIY66055.1 - 1.3 9.2 7.9 1.4 9.1 3.9 2.7 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C2H2_4 PF13894.6 KIY66055.1 - 2.8 9.0 10.2 14 6.9 0.7 4.0 3 1 0 3 3 3 0 C2H2-type zinc finger DZR PF12773.7 KIY66055.1 - 8.3 6.5 14.3 23 5.1 0.2 2.6 2 1 0 2 2 2 0 Double zinc ribbon MBOAT_2 PF13813.6 KIY66056.1 - 2.4e-19 69.4 3.2 2.4e-19 69.4 3.2 2.2 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family MFS_1 PF07690.16 KIY66057.1 - 4.9e-36 124.4 25.6 8.6e-36 123.6 25.6 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIY66057.1 - 8.1e-31 107.4 21.5 1e-29 103.8 21.5 2.5 1 1 0 1 1 1 1 Sugar (and other) transporter Cytochrome-c551 PF10643.9 KIY66057.1 - 0.023 14.3 0.1 0.049 13.2 0.1 1.6 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 FAD-oxidase_C PF02913.19 KIY66058.1 - 4.5e-53 180.4 0.1 6.4e-53 179.9 0.1 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KIY66058.1 - 2.3e-28 98.7 0.0 3.6e-28 98.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Cast PF10174.9 KIY66059.1 - 0.00045 18.6 2.3 0.00062 18.1 2.3 1.1 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone GAS PF13851.6 KIY66059.1 - 0.00088 18.7 4.0 0.0013 18.2 4.0 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding FAM76 PF16046.5 KIY66059.1 - 0.0036 16.7 0.5 0.0048 16.3 0.5 1.1 1 0 0 1 1 1 1 FAM76 protein EzrA PF06160.12 KIY66059.1 - 0.0038 15.5 0.8 0.0052 15.0 0.8 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA SHE3 PF17078.5 KIY66059.1 - 0.0075 16.0 3.1 0.011 15.4 3.1 1.2 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 Fib_alpha PF08702.10 KIY66059.1 - 0.0084 16.3 1.8 0.016 15.4 1.8 1.4 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family LRRFIP PF09738.9 KIY66059.1 - 0.016 14.7 2.7 0.025 14.1 2.7 1.3 1 0 0 1 1 1 0 LRRFIP family Filament PF00038.21 KIY66059.1 - 0.016 14.8 5.0 0.022 14.3 5.0 1.1 1 0 0 1 1 1 0 Intermediate filament protein DHR10 PF18595.1 KIY66059.1 - 0.02 14.9 4.7 0.034 14.2 4.7 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain HrpB7 PF09486.10 KIY66059.1 - 0.021 15.2 2.0 0.033 14.6 2.0 1.3 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) SlyX PF04102.12 KIY66059.1 - 0.023 15.3 5.7 0.21 12.2 1.3 2.4 1 1 1 2 2 2 0 SlyX UPF0242 PF06785.11 KIY66059.1 - 0.025 14.7 5.3 0.09 12.9 5.3 1.8 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ABC_tran_CTD PF16326.5 KIY66059.1 - 0.049 13.9 5.3 1.6 9.0 0.4 2.4 2 0 0 2 2 2 0 ABC transporter C-terminal domain DUF4349 PF14257.6 KIY66059.1 - 0.058 12.8 1.6 0.11 12.0 1.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) DUF641 PF04859.12 KIY66059.1 - 0.074 13.4 2.8 0.97 9.8 2.6 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) YlqD PF11068.8 KIY66059.1 - 0.11 12.9 2.9 0.17 12.3 2.9 1.2 1 0 0 1 1 1 0 YlqD protein TMF_DNA_bd PF12329.8 KIY66059.1 - 0.13 12.3 6.3 0.28 11.2 5.9 1.7 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF1664 PF07889.12 KIY66059.1 - 0.15 12.1 0.8 0.24 11.4 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) BRE1 PF08647.11 KIY66059.1 - 0.26 11.4 6.0 0.83 9.8 6.0 1.8 1 1 0 1 1 1 0 BRE1 E3 ubiquitin ligase Spc7 PF08317.11 KIY66059.1 - 0.3 9.9 5.1 0.42 9.4 5.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein TMPIT PF07851.13 KIY66059.1 - 0.39 9.9 1.0 0.54 9.5 1.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein MUG113 PF13455.6 KIY66061.1 - 4e-16 59.4 0.1 1.2e-15 57.9 0.0 1.8 2 0 0 2 2 2 1 Meiotically up-regulated gene 113 T5orf172 PF10544.9 KIY66061.1 - 3.4e-12 46.8 0.0 1.4e-10 41.6 0.0 2.4 2 0 0 2 2 2 1 T5orf172 domain ATG16 PF08614.11 KIY66063.1 - 0.0055 17.0 2.2 0.0095 16.2 2.2 1.4 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) PKcGMP_CC PF16808.5 KIY66063.1 - 0.14 12.0 0.4 0.33 10.8 0.4 1.6 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase ZapB PF06005.12 KIY66063.1 - 0.46 11.0 3.1 0.68 10.4 1.8 1.9 1 1 1 2 2 2 0 Cell division protein ZapB UCH_1 PF13423.6 KIY66064.1 - 3.4e-82 276.6 0.0 4.4e-82 276.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 KIY66064.1 - 5.8e-21 75.7 0.0 1.4e-20 74.5 0.0 1.7 2 0 0 2 2 2 1 Exonuclease UCH PF00443.29 KIY66064.1 - 0.0003 20.4 0.0 0.0007 19.2 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase WD40 PF00400.32 KIY66064.1 - 0.097 13.6 0.6 21 6.2 0.0 4.1 4 0 0 4 4 4 0 WD domain, G-beta repeat zf-RING_4 PF14570.6 KIY66065.1 - 3e-21 74.9 11.8 4.9e-21 74.3 11.8 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 KIY66065.1 - 3.4e-05 23.6 10.2 5.8e-05 22.9 10.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KIY66065.1 - 0.0048 16.7 9.9 0.093 12.6 5.3 2.5 1 1 1 2 2 2 2 Prokaryotic RING finger family 4 Baculo_IE-1 PF05290.11 KIY66065.1 - 0.052 13.5 3.6 0.11 12.5 3.6 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-RING_2 PF13639.6 KIY66065.1 - 0.067 13.5 13.0 0.12 12.7 13.0 1.4 1 0 0 1 1 1 0 Ring finger domain zf-UDP PF14569.6 KIY66065.1 - 0.076 13.1 3.9 0.17 12.0 3.9 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-C3HC4_2 PF13923.6 KIY66065.1 - 1.8 8.5 12.8 3.6 7.5 12.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KIY66065.1 - 2 8.5 7.1 6.3 6.9 7.4 1.8 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.25 KIY66065.1 - 4.6 7.2 13.3 8.1 6.4 13.3 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Epimerase PF01370.21 KIY66066.1 - 3.2e-16 59.5 0.2 1e-15 57.9 0.2 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KIY66066.1 - 2.5e-09 37.3 0.1 3.7e-09 36.7 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KIY66066.1 - 4.7e-09 35.8 0.0 4.9e-05 22.6 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.19 KIY66066.1 - 1.5e-08 34.0 0.0 2.7e-08 33.2 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 KIY66066.1 - 1.1e-06 28.4 0.4 2e-06 27.5 0.4 1.4 1 0 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 KIY66066.1 - 0.00059 19.3 0.0 0.00088 18.8 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase bZIP_2 PF07716.15 KIY66067.1 - 0.017 15.2 2.0 1.6 8.8 0.3 2.7 3 0 0 3 3 3 0 Basic region leucine zipper TSC22 PF01166.18 KIY66067.1 - 0.026 14.8 0.3 3.4 8.1 0.1 2.8 2 1 1 3 3 3 0 TSC-22/dip/bun family bZIP_1 PF00170.21 KIY66067.1 - 0.033 14.3 0.5 0.28 11.3 0.1 2.5 3 0 0 3 3 3 0 bZIP transcription factor GIT_CC PF16559.5 KIY66067.1 - 0.16 11.8 0.5 10 6.0 0.0 3.0 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor ADIP PF11559.8 KIY66067.1 - 0.23 11.5 1.0 0.45 10.6 0.2 1.7 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding TAFA PF12020.8 KIY66068.1 - 0.026 15.0 3.9 0.026 15.0 3.9 1.8 2 1 0 2 2 2 0 TAFA family Cupin_8 PF13621.6 KIY66069.1 - 1.5e-30 106.8 0.1 2e-30 106.3 0.1 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 KIY66069.1 - 3.5e-06 26.7 0.0 6.9e-06 25.7 0.0 1.6 1 1 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 KIY66069.1 - 1.2e-05 25.8 0.0 2.2e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 KIY66069.1 - 0.0016 18.1 0.0 0.0058 16.3 0.0 1.9 2 0 0 2 2 2 1 Cupin domain Cupin_1 PF00190.22 KIY66069.1 - 0.03 13.9 0.0 0.067 12.8 0.0 1.6 1 1 0 1 1 1 0 Cupin Cupin_3 PF05899.12 KIY66069.1 - 0.091 12.5 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) DUF3535 PF12054.8 KIY66070.1 - 2.3e-97 327.0 4.7 2e-95 320.6 0.0 4.0 5 0 0 5 5 5 1 Domain of unknown function (DUF3535) SNF2_N PF00176.23 KIY66070.1 - 1.4e-63 214.8 0.0 2.5e-63 213.9 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KIY66070.1 - 3.1e-16 59.7 0.0 7.1e-16 58.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.22 KIY66070.1 - 1.5e-11 43.5 20.8 0.29 11.5 0.0 9.8 10 0 0 10 10 9 4 HEAT repeat Vac14_Fab1_bd PF12755.7 KIY66070.1 - 7.4e-06 26.5 0.1 0.13 12.8 0.0 2.9 2 0 0 2 2 2 2 Vacuolar 14 Fab1-binding region ResIII PF04851.15 KIY66070.1 - 0.0011 19.0 0.0 0.0033 17.4 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HEAT_2 PF13646.6 KIY66070.1 - 0.0084 16.5 12.1 28 5.2 0.1 7.8 7 2 1 8 8 8 0 HEAT repeats HEAT_EZ PF13513.6 KIY66070.1 - 0.011 16.2 16.2 6.4 7.4 0.0 8.4 7 1 0 7 7 7 0 HEAT-like repeat DUF3385 PF11865.8 KIY66070.1 - 0.022 14.7 0.0 0.068 13.1 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3385) CLASP_N PF12348.8 KIY66070.1 - 0.1 12.2 0.0 0.79 9.2 0.0 2.6 2 0 0 2 2 2 0 CLASP N terminal TAF6_C PF07571.13 KIY66070.1 - 0.14 12.5 0.0 13 6.2 0.0 3.8 3 0 0 3 3 3 0 TAF6 C-terminal HEAT repeat domain Arm PF00514.23 KIY66070.1 - 0.16 12.1 0.2 5.4 7.2 0.0 3.6 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat FMO-like PF00743.19 KIY66071.1 - 4.1e-44 150.9 0.0 4.3e-35 121.1 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KIY66071.1 - 3.8e-23 82.2 0.0 7.7e-21 74.6 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KIY66071.1 - 2e-13 50.3 0.0 3.3e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KIY66071.1 - 1.6e-10 40.7 0.0 2.9e-09 36.5 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 KIY66071.1 - 6.6e-06 25.6 0.0 0.14 11.4 0.0 3.2 3 0 0 3 3 3 2 FAD binding domain NAD_binding_8 PF13450.6 KIY66071.1 - 7.8e-06 26.0 0.4 0.0011 19.2 0.0 3.0 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KIY66071.1 - 1.9e-05 24.7 0.0 8e-05 22.7 0.0 2.0 1 1 1 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 KIY66071.1 - 0.00014 21.2 0.0 0.011 14.9 0.0 2.3 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 KIY66071.1 - 0.0016 18.1 0.3 2.2 7.8 0.0 3.2 1 1 1 3 3 3 2 FAD dependent oxidoreductase HI0933_like PF03486.14 KIY66071.1 - 0.0035 16.1 0.5 0.074 11.7 0.1 2.7 3 0 0 3 3 3 1 HI0933-like protein Shikimate_DH PF01488.20 KIY66071.1 - 0.0049 16.9 0.1 0.42 10.7 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 KIY66071.1 - 0.016 15.6 0.0 0.55 10.7 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding FAD_binding_2 PF00890.24 KIY66071.1 - 0.024 13.7 0.2 1.1 8.3 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain ELFV_dehydrog PF00208.21 KIY66071.1 - 0.048 13.4 0.0 0.083 12.6 0.0 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Pyr_redox PF00070.27 KIY66071.1 - 0.058 13.9 0.5 2.2 8.9 0.0 2.6 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KIY66071.1 - 0.14 11.2 0.7 12 4.8 0.0 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A DEAD PF00270.29 KIY66073.1 - 4.8e-14 52.5 0.0 8.8e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIY66073.1 - 2e-08 34.5 0.0 4e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4451 PF14616.6 KIY66074.1 - 0.013 15.7 6.7 3.8 7.7 0.1 3.7 2 1 1 4 4 4 0 Domain of unknown function (DUF4451) Eapp_C PF10238.9 KIY66074.1 - 0.05 13.7 0.2 24 5.0 0.3 3.4 3 1 0 3 3 3 0 E2F-associated phosphoprotein ArsA_ATPase PF02374.15 KIY66075.1 - 8.9e-103 343.6 2.1 1.1e-102 343.3 2.1 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 KIY66075.1 - 1.4e-10 41.4 0.7 1.5e-09 38.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 KIY66075.1 - 4e-07 30.1 0.0 1e-06 28.8 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain SRP54 PF00448.22 KIY66075.1 - 0.0056 16.3 0.8 0.17 11.5 0.2 2.5 1 1 1 2 2 2 1 SRP54-type protein, GTPase domain CBP_BcsQ PF06564.12 KIY66075.1 - 0.013 15.0 0.0 0.054 13.0 0.0 1.8 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ Fer4_NifH PF00142.18 KIY66075.1 - 0.049 13.1 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family F-box-like PF12937.7 KIY66076.1 - 6.5e-09 35.6 0.3 1.5e-08 34.3 0.3 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY66076.1 - 0.037 13.9 0.6 0.28 11.1 0.6 2.5 1 1 0 1 1 1 0 F-box domain Symplekin_C PF12295.8 KIY66076.1 - 0.041 14.0 0.5 3.6 7.6 0.1 2.5 2 1 0 2 2 2 0 Symplekin tight junction protein C terminal p450 PF00067.22 KIY66077.1 - 6.5e-71 239.5 0.0 1.2e-70 238.6 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 MIF4G PF02854.19 KIY66079.1 - 2.4e-26 92.7 1.0 4e-26 92.0 1.0 1.3 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.17 KIY66079.1 - 2.2e-21 75.9 0.4 3.9e-20 71.9 0.1 2.9 2 1 0 2 2 2 1 MA3 domain PhoLip_ATPase_C PF16212.5 KIY66080.1 - 1.4e-70 237.9 27.0 2.5e-70 237.1 27.0 1.5 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KIY66080.1 - 1.1e-22 79.4 1.0 1.1e-22 79.4 1.0 2.2 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KIY66080.1 - 1.4e-13 51.6 2.0 5.5e-07 30.1 0.2 3.4 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KIY66080.1 - 6.8e-11 42.1 0.0 2.6e-10 40.3 0.0 1.9 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 KIY66080.1 - 1.5e-05 24.6 0.0 1.5e-05 24.6 0.0 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KIY66080.1 - 5.1e-05 23.1 0.5 0.0043 16.8 0.2 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KIY66080.1 - 0.076 13.4 0.1 1.9 8.9 0.1 2.5 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase RGS12_usC PF16612.5 KIY66082.1 - 0.2 12.1 0.2 0.36 11.3 0.2 1.4 1 0 0 1 1 1 0 C-terminal unstructured region of RGS12 FKBP_C PF00254.28 KIY66086.1 - 2e-30 105.0 0.0 2.5e-30 104.6 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase GramPos_pilinBB PF16569.5 KIY66086.1 - 0.1 13.5 0.0 0.14 13.0 0.0 1.1 1 0 0 1 1 1 0 Gram-positive pilin backbone subunit 2, Cna-B-like domain p450 PF00067.22 KIY66090.1 - 8.1e-68 229.2 0.0 1.4e-67 228.4 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Peptidase_S15 PF02129.18 KIY66091.1 - 1.2e-12 48.1 0.2 2.1e-12 47.2 0.1 1.4 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 KIY66091.1 - 1.6e-10 40.7 0.0 2.7e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KIY66091.1 - 1.3e-07 31.5 0.0 0.0038 16.9 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIY66091.1 - 1.3e-05 25.9 0.9 1.9e-05 25.4 0.9 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KIY66091.1 - 0.00049 19.6 0.2 0.053 13.0 0.3 2.5 2 1 0 2 2 2 1 Prolyl oligopeptidase family Smoa_sbd PF17885.1 KIY66091.1 - 0.0094 16.1 0.0 0.023 14.8 0.0 1.6 1 1 0 1 1 1 1 Styrene monooxygenase A putative substrate binding domain DLH PF01738.18 KIY66091.1 - 0.013 15.0 0.0 1.2 8.6 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family LIP PF03583.14 KIY66091.1 - 0.098 12.0 0.1 0.16 11.3 0.1 1.3 1 0 0 1 1 1 0 Secretory lipase Peptidase_S15 PF02129.18 KIY66092.1 - 2.4e-16 60.1 0.3 3.2e-16 59.7 0.3 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 KIY66092.1 - 2.3e-13 50.0 0.1 4.2e-13 49.1 0.1 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KIY66092.1 - 7e-10 39.9 0.2 1.6e-09 38.7 0.1 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KIY66092.1 - 7.7e-08 32.3 0.1 9.8e-05 22.1 0.2 2.2 1 1 0 2 2 2 2 alpha/beta hydrolase fold DLH PF01738.18 KIY66092.1 - 3.5e-07 30.0 0.1 0.0013 18.3 0.1 2.3 2 0 0 2 2 2 2 Dienelactone hydrolase family Peptidase_S9 PF00326.21 KIY66092.1 - 3.3e-06 26.7 0.2 0.0036 16.8 0.2 2.4 2 0 0 2 2 2 2 Prolyl oligopeptidase family Ser_hydrolase PF06821.13 KIY66092.1 - 0.00085 19.2 0.0 0.0015 18.4 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase AXE1 PF05448.12 KIY66092.1 - 0.057 12.1 0.1 1.2 7.8 0.1 2.3 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) Smoa_sbd PF17885.1 KIY66092.1 - 0.12 12.4 0.0 0.59 10.3 0.0 2.1 2 0 0 2 2 2 0 Styrene monooxygenase A putative substrate binding domain F-box-like PF12937.7 KIY66093.1 - 7.7e-07 28.9 0.0 1.8e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY66093.1 - 0.015 15.1 0.1 0.11 12.4 0.1 2.6 1 1 0 1 1 1 0 F-box domain Erf4 PF10256.9 KIY66094.1 - 1.4e-27 96.1 0.0 1.6e-27 95.9 0.0 1.0 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family bZIP_1 PF00170.21 KIY66095.1 - 7.8e-11 41.9 13.4 1.3e-10 41.2 13.4 1.4 1 0 0 1 1 1 1 bZIP transcription factor SHE3 PF17078.5 KIY66095.1 - 3e-05 23.9 6.1 4.3e-05 23.3 6.1 1.2 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 bZIP_2 PF07716.15 KIY66095.1 - 0.00045 20.2 15.3 0.00045 20.2 15.3 2.2 1 1 1 2 2 2 1 Basic region leucine zipper APC_u15 PF16636.5 KIY66095.1 - 0.048 14.1 0.7 0.048 14.1 0.7 2.8 2 1 1 3 3 3 0 Unstructured region on APC between APC_crr regions 5 and 6 DUF724 PF05266.14 KIY66095.1 - 0.063 13.1 5.9 0.18 11.7 5.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF724) bZIP_Maf PF03131.17 KIY66095.1 - 0.091 13.3 11.4 0.18 12.4 11.4 1.5 1 1 0 1 1 1 0 bZIP Maf transcription factor SlyX PF04102.12 KIY66095.1 - 0.18 12.5 2.3 0.37 11.4 2.3 1.5 1 0 0 1 1 1 0 SlyX TSC22 PF01166.18 KIY66095.1 - 0.29 11.5 2.7 0.98 9.8 2.7 1.8 1 1 0 1 1 1 0 TSC-22/dip/bun family UPF0242 PF06785.11 KIY66095.1 - 0.46 10.6 5.6 0.71 9.9 5.6 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DivIC PF04977.15 KIY66095.1 - 0.46 10.3 7.5 0.8 9.5 7.5 1.4 1 0 0 1 1 1 0 Septum formation initiator DUF5094 PF17015.5 KIY66095.1 - 0.91 9.6 5.1 1.6 8.8 5.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) ZapB PF06005.12 KIY66095.1 - 1.3 9.5 9.5 0.48 10.9 6.7 1.7 1 1 0 1 1 1 0 Cell division protein ZapB GvpL_GvpF PF06386.11 KIY66095.1 - 1.5 8.6 4.4 2.4 8.0 4.4 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF GIT_CC PF16559.5 KIY66095.1 - 1.7 8.5 5.1 3.5 7.6 5.1 1.5 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor MCPVI PF02993.14 KIY66095.1 - 2.1 8.1 10.8 3.1 7.6 0.8 2.6 2 0 0 2 2 2 0 Minor capsid protein VI NRBF2 PF08961.10 KIY66095.1 - 4 7.0 8.1 2.2 7.9 4.8 2.1 2 0 0 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator Brr6_like_C_C PF10104.9 KIY66096.1 - 6.8e-33 113.3 0.2 8.8e-33 112.9 0.2 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain CLP_protease PF00574.23 KIY66097.1 - 3.5e-74 248.6 0.1 2.8e-73 245.7 0.1 1.9 1 1 0 1 1 1 1 Clp protease TPR_12 PF13424.6 KIY66098.1 - 4e-13 49.5 1.9 2.4e-07 30.9 0.3 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 KIY66098.1 - 6.6e-09 35.4 6.7 6.6e-06 25.8 0.0 3.9 4 0 0 4 4 3 2 Tetratricopeptide repeat NB-ARC PF00931.22 KIY66098.1 - 6.4e-07 28.8 0.0 1.2e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain TPR_4 PF07721.14 KIY66098.1 - 2.4e-06 27.6 3.7 1.6 9.6 0.0 4.8 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KIY66098.1 - 4.5e-06 27.0 1.1 0.21 12.5 0.0 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat NACHT PF05729.12 KIY66098.1 - 6.9e-06 26.1 0.1 2.2e-05 24.4 0.0 1.9 2 0 0 2 2 1 1 NACHT domain TPR_19 PF14559.6 KIY66098.1 - 0.00033 21.1 1.2 0.11 13.0 0.1 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat CbiA PF01656.23 KIY66098.1 - 0.00037 20.5 0.0 0.0005 20.1 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.6 KIY66098.1 - 0.00097 19.4 0.0 0.003 17.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain TPR_6 PF13174.6 KIY66098.1 - 0.0018 18.8 1.2 6.5 7.6 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 KIY66098.1 - 0.0066 16.5 0.5 11 6.4 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat ATPase_2 PF01637.18 KIY66098.1 - 0.007 16.3 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_16 PF13191.6 KIY66098.1 - 0.0073 16.7 3.4 0.092 13.1 2.6 2.7 2 1 0 2 2 1 1 AAA ATPase domain CBP_BcsQ PF06564.12 KIY66098.1 - 0.021 14.3 0.1 0.038 13.5 0.1 1.4 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsQ AAA_31 PF13614.6 KIY66098.1 - 0.029 14.3 0.0 0.051 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KIY66098.1 - 0.094 12.4 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain TPR_8 PF13181.6 KIY66098.1 - 0.096 13.0 0.1 49 4.5 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat IstB_IS21 PF01695.17 KIY66098.1 - 0.096 12.4 0.2 0.21 11.3 0.0 1.7 2 0 0 2 2 1 0 IstB-like ATP binding protein PhoH PF02562.16 KIY66098.1 - 0.1 12.0 0.0 0.25 10.8 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein TPR_7 PF13176.6 KIY66098.1 - 0.11 12.6 2.5 24 5.3 0.0 4.1 4 0 0 4 4 3 0 Tetratricopeptide repeat AAA_18 PF13238.6 KIY66098.1 - 0.13 12.8 0.0 0.26 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KIY66098.1 - 0.14 11.4 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.14 KIY66098.1 - 0.16 12.0 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TPR_1 PF00515.28 KIY66098.1 - 2.3 8.2 4.4 27 4.8 0.1 3.1 4 0 0 4 4 2 0 Tetratricopeptide repeat CLP_protease PF00574.23 KIY66099.1 - 5.8e-39 133.9 0.3 1.3e-38 132.7 0.3 1.5 1 1 0 1 1 1 1 Clp protease EF-hand_1 PF00036.32 KIY66100.1 - 4.6e-22 75.9 1.4 6.8e-06 25.3 0.0 4.8 4 1 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 KIY66100.1 - 3.8e-20 70.0 0.4 1.6e-05 24.5 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 KIY66100.1 - 2.3e-19 69.6 0.0 2.3e-09 37.5 0.0 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KIY66100.1 - 3.5e-17 61.0 0.1 0.001 18.5 0.0 4.5 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 KIY66100.1 - 1.4e-14 53.7 0.9 2.8e-09 36.7 0.1 3.8 3 1 0 3 3 3 2 EF-hand domain pair HHV-5_US34A PF17087.5 KIY66100.1 - 0.091 12.9 0.1 0.15 12.2 0.1 1.2 1 0 0 1 1 1 0 Herpesvirus US34A protein family EF-hand_9 PF14658.6 KIY66100.1 - 0.12 12.8 0.1 11 6.5 0.0 3.4 3 1 0 3 3 3 0 EF-hand domain GUN4 PF05419.12 KIY66100.1 - 0.13 12.3 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 GUN4-like Piwi PF02171.17 KIY66101.1 - 1.4e-81 274.1 0.0 2e-81 273.5 0.0 1.3 1 0 0 1 1 1 1 Piwi domain ArgoL1 PF08699.10 KIY66101.1 - 1.3e-06 27.9 1.0 4.2e-06 26.3 1.0 1.9 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoN PF16486.5 KIY66101.1 - 0.00028 21.5 0.0 0.0006 20.4 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoMid PF16487.5 KIY66101.1 - 0.007 16.6 0.1 0.019 15.2 0.1 1.7 1 0 0 1 1 1 1 Mid domain of argonaute PAZ PF02170.22 KIY66101.1 - 0.032 14.0 0.0 0.06 13.2 0.0 1.4 1 0 0 1 1 1 0 PAZ domain ArgoL2 PF16488.5 KIY66101.1 - 0.14 12.5 0.0 0.44 10.9 0.0 2.0 1 0 0 1 1 1 0 Argonaute linker 2 domain Zn_clus PF00172.18 KIY66102.1 - 2.5e-06 27.5 4.8 4.8e-06 26.6 4.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Nop16 PF09420.10 KIY66103.1 - 1.3e-52 178.9 0.5 1.5e-52 178.7 0.5 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 QCR10 PF09796.9 KIY66104.1 - 5.3e-21 74.4 0.1 6.1e-21 74.2 0.1 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) HAD_2 PF13419.6 KIY66105.1 - 3.3e-08 33.8 0.0 5.5e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KIY66105.1 - 0.00019 21.4 0.0 0.0004 20.4 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 KIY66105.1 - 0.0019 18.5 0.0 0.0086 16.4 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Acid_PPase PF12689.7 KIY66105.1 - 0.028 14.3 0.0 0.042 13.7 0.0 1.3 1 0 0 1 1 1 0 Acid Phosphatase AP_endonuc_2 PF01261.24 KIY66105.1 - 0.1 12.0 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Got1 PF04178.12 KIY66106.1 - 2.4e-29 102.0 22.7 3.1e-29 101.7 22.7 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family DUF3040 PF11239.8 KIY66106.1 - 1.6 9.1 12.5 3.7 7.9 4.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) tRNA-synt_2 PF00152.20 KIY66108.1 - 1.8e-89 299.9 0.0 2.6e-89 299.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KIY66108.1 - 4e-11 42.7 0.1 7.5e-11 41.9 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain FMN_red PF03358.15 KIY66108.1 - 0.17 11.6 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 NADPH-dependent FMN reductase DUF3510 PF12022.8 KIY66108.1 - 1.7 9.1 4.0 22 5.4 3.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3510) PPTA PF01239.22 KIY66109.1 - 1.5e-49 164.3 16.1 6.2e-10 38.5 0.1 5.5 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat TPR_17 PF13431.6 KIY66109.1 - 0.14 12.6 0.2 26 5.5 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF4246 PF14033.6 KIY66110.1 - 3.7e-130 435.1 0.0 4.9e-130 434.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) Helicase_C PF00271.31 KIY66111.1 - 6.8e-17 61.8 0.1 3.7e-16 59.4 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KIY66111.1 - 1.8e-15 57.2 0.1 2.8e-15 56.5 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 KIY66111.1 - 6.1e-06 26.9 0.0 1.5e-05 25.6 0.0 1.7 1 0 0 1 1 1 1 RecQ zinc-binding EF-hand_7 PF13499.6 KIY66111.1 - 0.0034 17.8 0.0 0.0092 16.4 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair DprA_WH PF17782.1 KIY66111.1 - 0.041 14.0 0.1 0.083 13.0 0.1 1.5 1 0 0 1 1 1 0 DprA winged helix domain HTH_Crp_2 PF13545.6 KIY66111.1 - 0.11 12.4 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain DUF4246 PF14033.6 KIY66112.1 - 3.5e-137 458.2 0.0 4.2e-137 458.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) F-box-like PF12937.7 KIY66113.1 - 0.00064 19.6 2.5 0.00083 19.2 0.4 2.3 2 1 0 2 2 2 1 F-box-like HAGH_C PF16123.5 KIY66114.1 - 5.3e-20 71.7 0.0 9.2e-20 71.0 0.0 1.4 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 KIY66114.1 - 5.5e-07 29.8 3.0 3.1e-05 24.1 3.0 2.3 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KIY66114.1 - 0.017 14.6 0.1 0.095 12.2 0.1 2.1 1 1 0 1 1 1 0 Beta-lactamase superfamily domain PepSY_TM PF03929.16 KIY66115.1 - 0.0007 19.4 0.0 0.00087 19.0 0.0 1.1 1 0 0 1 1 1 1 PepSY-associated TM region EphA2_TM PF14575.6 KIY66115.1 - 0.044 14.7 0.0 0.067 14.1 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain BatA PF07584.11 KIY66115.1 - 0.051 14.0 0.0 0.085 13.2 0.0 1.3 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal 7tm_7 PF08395.12 KIY66115.1 - 0.19 10.9 0.0 0.24 10.6 0.0 1.1 1 0 0 1 1 1 0 7tm Chemosensory receptor SKG6 PF08693.10 KIY66115.1 - 6.5 6.2 6.6 13 5.3 6.6 1.6 1 1 0 1 1 1 0 Transmembrane alpha-helix domain SRP54 PF00448.22 KIY66116.1 - 7.5e-47 159.5 0.5 1.1e-45 155.7 0.5 2.6 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.13 KIY66116.1 - 1.3e-43 150.0 12.2 3.9e-42 145.2 7.9 2.6 1 1 1 2 2 2 1 Signal recognition particle, alpha subunit, N-terminal SRP54_N PF02881.19 KIY66116.1 - 1.2e-07 31.9 0.0 6.3e-07 29.5 0.0 2.3 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain MeaB PF03308.16 KIY66116.1 - 3.1e-06 26.4 0.6 2.5e-05 23.4 0.1 2.4 2 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 KIY66116.1 - 0.007 16.6 0.1 0.091 13.0 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.6 KIY66116.1 - 0.0076 16.0 0.0 0.021 14.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KIY66116.1 - 0.0097 15.6 0.0 0.022 14.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 KIY66116.1 - 0.011 15.8 0.0 0.032 14.3 0.0 1.8 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 KIY66116.1 - 0.012 14.8 0.6 1.8 7.7 0.1 2.5 1 1 1 2 2 2 0 Anion-transporting ATPase NTPase_1 PF03266.15 KIY66116.1 - 0.022 14.6 0.1 0.07 13.0 0.1 1.8 1 1 0 1 1 1 0 NTPase Fer4_NifH PF00142.18 KIY66116.1 - 0.033 13.6 0.0 0.072 12.5 0.0 1.5 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_31 PF13614.6 KIY66116.1 - 0.074 13.0 0.1 1.6 8.6 0.0 2.3 1 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KIY66116.1 - 0.081 13.3 0.0 1.4 9.3 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain MMR_HSR1 PF01926.23 KIY66116.1 - 0.12 12.4 0.9 1.3 9.1 0.9 2.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase Glyco_hydro_61 PF03443.14 KIY66117.1 - 1.7e-48 165.3 0.0 2.1e-48 165.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 F-box-like PF12937.7 KIY66118.1 - 1.7e-06 27.8 0.9 4.7e-06 26.4 0.9 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY66118.1 - 0.0021 17.9 0.0 0.0092 15.8 0.0 2.2 1 1 0 1 1 1 1 F-box domain HTH_50 PF18024.1 KIY66118.1 - 0.092 12.4 0.2 0.22 11.1 0.2 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain LRR_4 PF12799.7 KIY66118.1 - 0.12 12.8 1.0 6.9 7.2 0.1 3.1 1 1 2 3 3 3 0 Leucine Rich repeats (2 copies) TPR_14 PF13428.6 KIY66119.1 - 1.7e-11 43.9 23.4 1.1 10.3 0.1 11.9 11 3 3 14 14 12 3 Tetratricopeptide repeat TPR_19 PF14559.6 KIY66119.1 - 2.5e-07 31.1 4.2 0.34 11.4 0.4 5.3 4 0 0 4 4 4 2 Tetratricopeptide repeat Suf PF05843.14 KIY66119.1 - 1.2e-06 28.8 9.0 0.00032 20.8 0.4 5.7 5 1 0 6 6 6 1 Suppressor of forked protein (Suf) Mad3_BUB1_I PF08311.12 KIY66119.1 - 1.3e-06 28.4 7.2 1.7 8.7 0.2 6.4 5 1 1 6 6 6 3 Mad3/BUB1 homology region 1 TPR_2 PF07719.17 KIY66119.1 - 6.8e-06 25.8 16.1 0.4 10.9 0.2 7.9 9 0 0 9 9 8 3 Tetratricopeptide repeat NRDE-2 PF08424.10 KIY66119.1 - 2.3e-05 23.7 6.5 0.11 11.6 0.1 5.5 2 2 2 5 5 5 2 NRDE-2, necessary for RNA interference TPR_12 PF13424.6 KIY66119.1 - 0.0024 18.1 7.6 4.7 7.6 0.4 5.8 5 1 0 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 KIY66119.1 - 0.0028 17.4 3.4 19 5.3 0.0 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 KIY66119.1 - 0.0052 16.9 9.7 27 5.3 0.0 7.0 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 KIY66119.1 - 0.009 16.0 3.2 8.2 6.7 0.0 6.4 8 0 0 8 8 8 1 Tetratricopeptide repeat HAT PF02184.16 KIY66119.1 - 0.08 12.9 11.0 3.7 7.6 0.1 6.6 7 0 0 7 7 7 0 HAT (Half-A-TPR) repeat DUF5339 PF17274.2 KIY66119.1 - 1.3 9.9 5.3 12 6.8 0.4 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5339) CEP209_CC5 PF16574.5 KIY66119.1 - 2.2 8.5 7.3 0.19 11.9 1.2 2.4 3 0 0 3 3 2 0 Coiled-coil region of centrosome protein CE290 TPR_16 PF13432.6 KIY66119.1 - 2.2 9.0 9.7 12 6.7 0.1 5.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KIY66119.1 - 2.9 8.7 10.3 88 4.1 0.0 6.3 7 0 0 7 7 6 0 Tetratricopeptide repeat ADH_zinc_N PF00107.26 KIY66120.1 - 1.7e-12 47.5 0.0 2.7e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIY66120.1 - 2.4e-09 37.0 0.0 3.9e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KIY66120.1 - 1.7e-05 25.9 0.0 2.5e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KIY66121.1 - 1.9e-11 44.1 0.0 3.1e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIY66121.1 - 9.3e-09 35.1 0.0 1.7e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KIY66121.1 - 0.00018 22.6 0.0 0.00028 21.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Dioxygenase_C PF00775.21 KIY66123.1 - 9.6e-08 31.7 0.2 1.6e-07 31.0 0.2 1.3 1 0 0 1 1 1 1 Dioxygenase HMG_box PF00505.19 KIY66124.1 - 3.3e-10 40.2 0.0 5.7e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KIY66124.1 - 0.0025 18.4 0.0 0.0047 17.5 0.0 1.5 1 0 0 1 1 1 1 HMG-box domain Brix PF04427.18 KIY66129.1 - 4.2e-45 154.2 0.0 5.8e-45 153.8 0.0 1.2 1 0 0 1 1 1 1 Brix domain BUD22 PF09073.10 KIY66129.1 - 0.44 9.8 29.8 0.82 8.9 29.8 1.4 1 0 0 1 1 1 0 BUD22 Paf1 PF03985.13 KIY66129.1 - 0.53 9.2 20.4 0.7 8.8 20.4 1.2 1 0 0 1 1 1 0 Paf1 PPL5 PF18168.1 KIY66129.1 - 2.5 7.3 8.5 6.4 6.0 8.5 1.7 1 1 0 1 1 1 0 Prim-pol family 5 Nop25 PF09805.9 KIY66129.1 - 7.7 7.0 27.5 17 5.8 27.5 1.5 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Dioxygenase_C PF00775.21 KIY66130.1 - 3.7e-08 33.0 0.2 6.7e-08 32.2 0.2 1.4 1 0 0 1 1 1 1 Dioxygenase Goodbye PF17109.5 KIY66135.1 - 1.9e-07 31.5 0.0 4.2e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 fungal STAND N-terminal Goodbye domain GP3_package PF16677.5 KIY66135.1 - 0.098 12.8 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 DNA-packaging protein gp3 PAH PF02671.21 KIY66135.1 - 0.12 12.6 0.2 0.48 10.6 0.1 2.0 2 0 0 2 2 2 0 Paired amphipathic helix repeat zf-MYND PF01753.18 KIY66136.1 - 1.2e-08 34.9 10.0 2.8e-08 33.7 10.0 1.7 1 0 0 1 1 1 1 MYND finger Meleagrin PF08189.11 KIY66136.1 - 0.2 11.4 6.9 1 9.1 6.9 2.3 1 0 0 1 1 1 0 Meleagrin/Cygnin family zf-MYND PF01753.18 KIY66138.1 - 4.7e-09 36.2 5.7 4.7e-09 36.2 5.7 1.9 2 0 0 2 2 2 1 MYND finger zf-MYND PF01753.18 KIY66139.1 - 9.5e-10 38.4 7.3 1.8e-09 37.5 7.3 1.5 1 0 0 1 1 1 1 MYND finger Alginate_lyase PF05426.12 KIY66141.1 - 2.2e-14 53.7 2.1 3.7e-13 49.6 2.1 2.0 1 1 0 1 1 1 1 Alginate lyase ABC_tran PF00005.27 KIY66142.1 - 1.9e-15 57.6 0.0 5e-15 56.2 0.0 1.7 2 0 0 2 2 2 1 ABC transporter ABC_ATPase PF09818.9 KIY66142.1 - 2.2e-05 23.4 0.2 0.032 13.1 0.2 2.2 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_16 PF13191.6 KIY66142.1 - 0.0012 19.2 0.0 0.0019 18.6 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 KIY66142.1 - 0.0021 17.6 0.1 0.42 10.0 0.0 2.2 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KIY66142.1 - 0.0034 17.1 0.1 0.0076 16.0 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 KIY66142.1 - 0.0062 16.4 0.2 0.036 13.9 0.1 2.0 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KIY66142.1 - 0.016 14.9 0.0 0.023 14.4 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KIY66142.1 - 0.03 14.6 0.0 0.16 12.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 KIY66142.1 - 0.037 13.1 0.1 0.12 11.5 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_24 PF13479.6 KIY66142.1 - 0.063 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KIY66142.1 - 0.097 12.7 0.0 2.4 8.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KIY66142.1 - 0.11 13.0 0.0 0.18 12.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 KIY66142.1 - 0.15 12.2 0.0 0.29 11.2 0.0 1.4 1 0 0 1 1 1 0 Dynamin family Zeta_toxin PF06414.12 KIY66142.1 - 0.15 11.3 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin ATPase_2 PF01637.18 KIY66142.1 - 0.17 11.8 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Phosphorylase PF00343.20 KIY66143.1 - 4.4e-296 983.9 0.0 5.1e-296 983.7 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase HA70_C PF17993.1 KIY66143.1 - 0.13 12.3 0.0 9.8 6.2 0.0 2.5 2 0 0 2 2 2 0 Haemagglutinin 70 C-terminal domain Pkinase PF00069.25 KIY66144.1 - 8.1e-35 120.4 0.2 2.5e-34 118.9 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY66144.1 - 2e-23 83.0 0.0 3e-23 82.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIY66144.1 - 1.5e-05 24.0 0.0 2.4e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KIY66144.1 - 0.0028 17.0 0.6 0.005 16.2 0.6 1.4 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KIY66144.1 - 0.0034 16.4 0.0 0.0082 15.1 0.0 1.6 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KIY66144.1 - 0.0072 16.3 0.5 0.021 14.8 0.1 1.9 2 1 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 KIY66144.1 - 0.015 14.9 1.1 0.04 13.5 0.1 2.1 2 0 0 2 2 2 0 RIO1 family Seadorna_VP7 PF07387.11 KIY66144.1 - 0.049 12.7 0.2 0.084 11.9 0.2 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 PIP49_C PF12260.8 KIY66144.1 - 0.086 12.5 0.3 0.19 11.3 0.0 1.7 2 0 0 2 2 2 0 Protein-kinase domain of FAM69 PCI PF01399.27 KIY66145.1 - 1.6e-09 38.2 0.2 2.2e-08 34.5 0.0 2.6 3 0 0 3 3 3 1 PCI domain MFS_1 PF07690.16 KIY66146.1 - 5e-29 101.3 32.3 6.7e-29 100.9 32.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily NCE101 PF11654.8 KIY66146.1 - 0.081 12.6 0.0 0.29 10.9 0.0 1.9 1 0 0 1 1 1 0 Non-classical export protein 1 zf-C2H2 PF00096.26 KIY66147.1 - 0.00046 20.5 6.2 0.057 13.9 0.4 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIY66147.1 - 0.00054 20.6 7.4 0.14 13.1 0.8 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KIY66147.1 - 0.039 13.7 2.0 0.63 9.8 0.1 2.7 2 0 0 2 2 2 0 zinc-finger C2H2-type NMO PF03060.15 KIY66148.1 - 1.6e-39 136.2 9.8 6.1e-38 131.0 9.8 2.4 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KIY66148.1 - 6.4e-09 35.3 0.0 3.3e-07 29.7 0.0 2.1 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KIY66148.1 - 0.0001 21.4 0.7 0.0001 21.4 0.7 1.8 2 0 0 2 2 2 1 FMN-dependent dehydrogenase DHO_dh PF01180.21 KIY66148.1 - 0.015 14.5 0.4 0.028 13.6 0.4 1.5 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase Glu_synthase PF01645.17 KIY66148.1 - 0.023 13.8 3.4 0.052 12.7 3.4 1.5 1 1 0 1 1 1 0 Conserved region in glutamate synthase Thaumatin PF00314.17 KIY66150.1 - 1.5e-14 54.2 5.9 3.5e-14 52.9 1.6 2.0 1 1 1 2 2 2 2 Thaumatin family Pkinase PF00069.25 KIY66151.1 - 2.8e-25 89.2 0.1 1.1e-24 87.3 0.1 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY66151.1 - 4.5e-19 68.7 0.0 6.3e-19 68.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 KIY66151.1 - 1.3e-05 24.9 0.0 2e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 KIY66151.1 - 0.056 12.7 0.0 0.082 12.2 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Coatamer_beta_C PF07718.12 KIY66152.1 - 0.047 13.6 0.0 0.047 13.6 0.0 1.1 1 0 0 1 1 1 0 Coatomer beta C-terminal region Nop52 PF05997.12 KIY66152.1 - 0.14 12.0 0.0 0.14 12.0 0.0 1.1 1 0 0 1 1 1 0 Nucleolar protein,Nop52 Myb_DNA-bind_3 PF12776.7 KIY66153.1 - 9.2e-09 36.2 0.0 1.2e-08 35.8 0.0 1.2 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 KIY66153.1 - 3e-06 27.5 0.0 4e-06 27.1 0.0 1.4 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 KIY66153.1 - 0.011 15.9 0.0 0.026 14.7 0.0 1.6 1 1 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KIY66154.1 - 1.9e-16 59.9 0.0 4.6e-10 39.5 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KIY66154.1 - 1.8e-11 44.1 0.0 1.4e-05 25.3 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 KIY66154.1 - 0.0018 18.3 0.0 0.16 12.0 0.0 2.3 2 0 0 2 2 2 1 SLIDE Pkinase PF00069.25 KIY66155.1 - 1.3e-26 93.6 0.0 1.7e-26 93.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY66155.1 - 4.5e-16 58.9 0.0 6e-16 58.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 KIY66155.1 - 4e-07 29.8 0.0 8.5e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 KIY66155.1 - 1.9e-05 23.6 0.1 2.8e-05 23.1 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KIY66155.1 - 0.00045 20.2 0.8 0.00084 19.3 0.1 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KIY66155.1 - 0.011 14.7 0.0 0.015 14.2 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase PF00069.25 KIY66156.1 - 3e-20 72.7 0.0 3.7e-20 72.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY66156.1 - 2.3e-11 43.5 0.0 2.9e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 KIY66156.1 - 2.3e-05 24.1 0.0 3.7e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KIY66156.1 - 0.0003 20.8 0.8 0.00044 20.3 0.1 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KIY66156.1 - 0.00047 19.0 0.3 0.00063 18.6 0.3 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KIY66156.1 - 0.0012 18.2 0.0 0.01 15.2 0.1 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KIY66156.1 - 0.011 14.7 0.0 0.015 14.3 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 KIY66156.1 - 0.095 11.7 0.1 0.14 11.2 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Cation_efflux PF01545.21 KIY66157.1 - 2.1e-21 76.6 6.4 2.5e-21 76.3 6.4 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KIY66157.1 - 8.8e-12 45.0 1.3 1.4e-11 44.4 1.3 1.3 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter WW PF00397.26 KIY66160.1 - 5.3e-09 36.0 1.8 1.1e-08 35.0 1.8 1.6 1 0 0 1 1 1 1 WW domain DUF2076 PF09849.9 KIY66160.1 - 0.95 9.4 24.2 0.023 14.7 16.6 1.8 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) TraT PF05818.12 KIY66160.1 - 4.8 6.8 5.0 8 6.1 5.0 1.3 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein LCCL PF03815.19 KIY66161.1 - 4.1e-15 55.7 0.0 7.4e-15 54.8 0.0 1.4 1 0 0 1 1 1 1 LCCL domain UcrQ PF02939.16 KIY66161.1 - 0.019 14.9 0.0 0.046 13.6 0.0 1.6 1 0 0 1 1 1 0 UcrQ family GDI PF00996.18 KIY66162.1 - 2.8e-221 734.6 0.1 3.2e-221 734.4 0.1 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor PemK_toxin PF02452.17 KIY66162.1 - 0.1 13.0 0.6 1.3 9.5 0.5 2.6 2 1 1 3 3 3 0 PemK-like, MazF-like toxin of type II toxin-antitoxin system Myb_DNA-bind_2 PF08914.11 KIY66163.1 - 0.032 14.4 6.3 0.22 11.7 0.0 3.1 3 0 0 3 3 3 0 Rap1 Myb domain Aldedh PF00171.22 KIY66164.1 - 1.6e-130 435.7 0.0 1.9e-130 435.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KIY66164.1 - 0.0004 19.6 0.0 0.00087 18.4 0.0 1.5 2 0 0 2 2 2 1 Acyl-CoA reductase (LuxC) Mito_carr PF00153.27 KIY66165.1 - 3.8e-31 106.9 8.9 2e-15 56.5 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Cgr1 PF03879.14 KIY66166.1 - 2.5e-26 92.1 22.6 2.8e-26 92.0 22.6 1.0 1 0 0 1 1 1 1 Cgr1 family Macoilin PF09726.9 KIY66166.1 - 1.8 7.0 11.3 1.8 7.0 11.3 1.0 1 0 0 1 1 1 0 Macoilin family Mpv17_PMP22 PF04117.12 KIY66167.1 - 4.1e-10 39.8 1.2 6.5e-10 39.1 1.2 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family DUF4229 PF14012.6 KIY66167.1 - 0.43 10.7 0.1 0.43 10.7 0.1 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF4229) Methyltransf_2 PF00891.18 KIY66168.1 - 1.3e-23 83.4 0.1 4.8e-20 71.7 0.0 2.2 2 0 0 2 2 2 2 O-methyltransferase domain RPA_C PF08784.11 KIY66168.1 - 0.00077 20.1 0.0 0.0016 19.0 0.0 1.5 1 0 0 1 1 1 1 Replication protein A C terminal Methyltransf_12 PF08242.12 KIY66168.1 - 0.0011 19.7 0.0 0.0031 18.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain HTH_36 PF13730.6 KIY66168.1 - 0.15 12.0 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Filament PF00038.21 KIY66169.1 - 1.8e-05 24.5 102.0 0.0016 18.1 8.0 6.4 2 1 3 5 5 5 3 Intermediate filament protein Spc7 PF08317.11 KIY66169.1 - 2.8e-05 23.2 128.8 0.0066 15.4 16.7 7.2 1 1 6 7 7 7 5 Spc7 kinetochore protein BST2 PF16716.5 KIY66169.1 - 0.0057 17.2 7.9 0.0057 17.2 7.9 9.7 3 3 6 9 9 9 2 Bone marrow stromal antigen 2 DHR10 PF18595.1 KIY66169.1 - 0.0073 16.4 5.5 0.0073 16.4 5.5 9.4 4 2 3 8 8 8 3 Designed helical repeat protein 10 domain CENP-F_leu_zip PF10473.9 KIY66169.1 - 0.0084 16.1 17.8 0.0084 16.1 17.8 8.0 1 1 5 7 7 7 4 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.12 KIY66169.1 - 0.15 12.1 73.7 0.26 11.4 1.8 9.7 2 1 6 9 9 9 0 Protein of unknown function (DUF1664) DUF1825 PF08855.10 KIY66169.1 - 1.2 9.1 4.9 0.52 10.3 0.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1825) DUF3584 PF12128.8 KIY66169.1 - 2.4 5.6 119.6 0.0044 14.6 58.3 4.2 1 1 3 4 4 4 0 Protein of unknown function (DUF3584) DUF5082 PF16888.5 KIY66169.1 - 3.2 8.1 77.0 0.1 12.9 1.1 8.5 4 3 6 10 10 10 0 Domain of unknown function (DUF5082) Fez1 PF06818.15 KIY66169.1 - 7.2 7.0 111.8 0.027 14.9 15.9 7.4 2 1 6 8 8 8 0 Fez1 His_Phos_1 PF00300.22 KIY66170.1 - 1.1e-36 126.4 0.0 1.4e-36 126.0 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) HD PF01966.22 KIY66171.1 - 4.4e-14 52.8 0.2 1.4e-13 51.1 0.0 1.9 2 1 0 2 2 2 1 HD domain DUF2027 PF09640.10 KIY66171.1 - 0.09 12.4 1.4 0.19 11.3 1.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2027) Glyco_hydro_2_N PF02837.18 KIY66172.1 - 2e-12 47.3 0.6 8.3e-12 45.3 0.6 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain BetaGal_dom4_5 PF13364.6 KIY66172.1 - 4.1e-05 24.1 0.3 0.00013 22.5 0.3 1.9 1 0 0 1 1 1 1 Beta-galactosidase jelly roll domain Glyco_hydro_2 PF00703.21 KIY66172.1 - 0.00034 21.2 0.1 0.0021 18.7 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Sec39 PF08314.11 KIY66173.1 - 8e-91 305.7 0.0 1.1e-90 305.3 0.0 1.0 1 0 0 1 1 1 1 Secretory pathway protein Sec39 TPR_14 PF13428.6 KIY66173.1 - 0.15 13.0 1.8 1.9 9.5 0.8 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat WD40 PF00400.32 KIY66174.1 - 4.9e-25 87.3 0.5 1.1e-06 29.2 0.0 5.9 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY66174.1 - 1.2e-09 38.3 0.1 0.31 11.4 0.0 4.6 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 KIY66174.1 - 0.00052 19.7 0.0 0.00084 19.0 0.0 1.4 1 0 0 1 1 1 1 PQQ-like domain Cytochrom_D1 PF02239.16 KIY66174.1 - 0.084 11.4 0.0 0.26 9.8 0.0 1.8 2 0 0 2 2 2 0 Cytochrome D1 heme domain HhH-GPD PF00730.25 KIY66175.1 - 3.8e-15 56.3 0.0 8.2e-15 55.2 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KIY66175.1 - 1.3e-06 28.0 0.0 4.4e-06 26.3 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix motif PBP1_TM PF14812.6 KIY66175.1 - 0.56 10.6 8.3 1.5 9.3 8.3 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal WD40 PF00400.32 KIY66176.1 - 2.1e-35 120.2 16.7 6.6e-11 42.6 0.1 8.1 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY66176.1 - 1e-09 38.6 1.5 0.011 16.1 0.0 4.5 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIY66176.1 - 5.7e-07 28.8 1.5 0.14 11.1 0.0 4.1 2 2 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 KIY66176.1 - 0.0015 17.4 0.2 0.17 10.6 0.0 3.1 2 2 2 4 4 4 1 Nup133 N terminal like Hira PF07569.11 KIY66176.1 - 0.0015 18.3 0.1 0.75 9.5 0.0 3.0 1 1 2 3 3 3 2 TUP1-like enhancer of split PALB2_WD40 PF16756.5 KIY66176.1 - 0.0016 17.4 2.0 0.0043 16.0 0.1 2.5 3 0 0 3 3 3 1 Partner and localizer of BRCA2 WD40 domain Nup160 PF11715.8 KIY66176.1 - 0.021 13.5 0.3 1.3 7.6 0.0 3.0 2 2 0 3 3 3 0 Nucleoporin Nup120/160 PTPlike_phytase PF14566.6 KIY66178.1 - 3.7e-07 30.4 0.0 9.8e-07 29.0 0.0 1.7 1 1 1 2 2 2 1 Inositol hexakisphosphate DSPc PF00782.20 KIY66178.1 - 1e-05 25.4 0.0 1.2e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KIY66178.1 - 4.4e-05 23.6 0.1 0.00026 21.0 0.1 2.0 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 KIY66178.1 - 0.00029 20.5 0.0 0.00038 20.1 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 KIY66178.1 - 0.0046 16.6 0.0 0.007 16.0 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family DUF442 PF04273.13 KIY66178.1 - 0.01 15.9 0.0 0.017 15.2 0.0 1.4 1 1 0 1 1 1 1 Putative phosphatase (DUF442) CDKN3 PF05706.12 KIY66178.1 - 0.031 13.9 0.0 0.041 13.6 0.0 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) HhH-GPD PF00730.25 KIY66179.1 - 8.8e-18 64.7 0.0 1.6e-17 63.9 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KIY66179.1 - 6.2e-05 22.7 0.0 0.00014 21.5 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif Sialidase PF02973.16 KIY66179.1 - 0.13 11.7 0.0 0.61 9.6 0.1 1.9 1 1 1 2 2 2 0 Sialidase, N-terminal domain HHH_5 PF14520.6 KIY66179.1 - 1 10.0 3.1 6.8 7.4 0.0 2.8 3 0 0 3 3 3 0 Helix-hairpin-helix domain TFIIIC_delta PF12657.7 KIY66180.1 - 3.1e-23 82.7 1.5 6.4e-23 81.6 1.5 1.6 1 0 0 1 1 1 1 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.7 KIY66180.1 - 4.4e-20 71.5 0.6 1e-19 70.3 0.6 1.6 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex Zn_clus PF00172.18 KIY66181.1 - 3.1e-07 30.4 12.8 4.8e-07 29.8 12.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BNR_4 PF15892.5 KIY66182.1 - 2.3e-75 253.5 6.4 3.3e-75 253.0 6.4 1.2 1 0 0 1 1 1 1 BNR repeat-containing family member DUF3533 PF12051.8 KIY66183.1 - 1.2e-85 287.8 13.5 1.4e-85 287.5 13.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) adh_short PF00106.25 KIY66184.1 - 1.8e-12 47.2 0.0 2.9e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIY66184.1 - 2.7e-12 46.8 0.0 4.1e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIY66184.1 - 2.8e-06 27.4 0.0 4.5e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 KIY66184.1 - 2.5e-05 24.6 0.0 6.9e-05 23.1 0.0 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain LCM PF04072.14 KIY66184.1 - 0.0047 16.9 0.0 0.0077 16.2 0.0 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase DUF3842 PF12953.7 KIY66184.1 - 0.048 14.0 0.2 0.083 13.3 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3842) F420_oxidored PF03807.17 KIY66184.1 - 0.14 12.8 0.2 0.3 11.7 0.2 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent EF1G PF00647.19 KIY66185.1 - 2.7e-41 140.0 0.0 4.1e-41 139.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C_3 PF14497.6 KIY66185.1 - 8.1e-09 35.6 0.0 2.3e-08 34.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KIY66185.1 - 9.3e-09 35.5 0.0 9.3e-09 35.5 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KIY66185.1 - 1.1e-07 32.0 1.4 1.9e-07 31.2 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KIY66185.1 - 1.2e-06 28.5 0.0 3.4e-06 27.0 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KIY66185.1 - 5.3e-05 23.6 0.0 0.00015 22.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain SspB PF04386.13 KIY66185.1 - 0.078 12.9 2.8 0.12 12.2 2.8 1.2 1 0 0 1 1 1 0 Stringent starvation protein B Ribosomal_60s PF00428.19 KIY66185.1 - 0.4 11.3 6.1 0.85 10.3 6.1 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein Pox_Ag35 PF03286.14 KIY66185.1 - 0.44 10.3 5.5 0.61 9.8 5.5 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein OAD_gamma PF04277.13 KIY66185.1 - 1.6 9.3 7.9 3.3 8.4 7.9 1.5 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain G_glu_transpept PF01019.21 KIY66186.1 - 5.5e-144 480.7 0.0 6.3e-144 480.5 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Prefoldin_2 PF01920.20 KIY66187.1 - 7.8e-18 64.4 8.3 8.8e-18 64.2 8.3 1.1 1 0 0 1 1 1 1 Prefoldin subunit End3 PF12761.7 KIY66187.1 - 0.0082 16.3 2.8 0.011 16.0 2.8 1.2 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 ADIP PF11559.8 KIY66187.1 - 0.099 12.7 8.3 0.16 12.1 3.7 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding MCU PF04678.13 KIY66187.1 - 0.2 11.7 3.9 0.26 11.4 3.9 1.2 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Prefoldin PF02996.17 KIY66187.1 - 0.23 11.4 8.7 0.45 10.4 4.4 2.1 1 1 1 2 2 2 0 Prefoldin subunit FlaC_arch PF05377.11 KIY66187.1 - 0.39 11.1 4.8 9.1 6.8 0.0 2.6 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) MIP-T3_C PF17749.1 KIY66187.1 - 1.2 9.1 9.8 0.22 11.5 5.7 1.7 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region Swi5 PF07061.11 KIY66187.1 - 1.7 8.8 8.2 12 6.1 0.2 2.3 1 1 1 2 2 2 0 Swi5 Uso1_p115_C PF04871.13 KIY66187.1 - 1.8 9.0 9.8 5.1 7.5 9.8 1.8 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF2205 PF10224.9 KIY66187.1 - 2.5 8.1 6.7 16 5.6 0.3 2.8 1 1 2 3 3 3 0 Short coiled-coil protein DivIC PF04977.15 KIY66187.1 - 3.5 7.5 11.4 0.67 9.8 0.7 2.5 2 1 0 2 2 2 0 Septum formation initiator APG6_N PF17675.1 KIY66187.1 - 6.3 7.3 11.2 25 5.4 11.2 1.8 1 1 0 1 1 1 0 Apg6 coiled-coil region Ribosomal_S17 PF00366.20 KIY66188.1 - 2e-19 69.4 1.9 2.8e-19 69.0 1.9 1.2 1 0 0 1 1 1 1 Ribosomal protein S17 ILVD_EDD PF00920.21 KIY66188.1 - 0.0038 15.9 0.5 0.0053 15.4 0.0 1.3 2 0 0 2 2 2 1 Dehydratase family Herpes_DNAp_acc PF04929.12 KIY66189.1 - 0.013 14.5 5.2 0.019 14.0 5.2 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DUF3246 PF11596.8 KIY66189.1 - 0.3 10.5 5.0 0.078 12.4 1.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) CDC45 PF02724.14 KIY66189.1 - 0.45 8.7 8.7 0.74 8.0 8.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Peptidase_M41 PF01434.18 KIY66190.1 - 2.3e-58 197.2 0.0 2.3e-58 197.2 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M41 AAA PF00004.29 KIY66190.1 - 6.9e-43 146.2 0.0 1.3e-42 145.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KIY66190.1 - 5e-13 48.6 0.1 1.3e-12 47.2 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 KIY66190.1 - 2.2e-11 44.1 0.0 4.8e-11 43.0 0.0 1.6 1 0 0 1 1 1 1 FtsH Extracellular AAA_16 PF13191.6 KIY66190.1 - 0.0016 18.8 0.1 0.059 13.7 0.1 2.8 1 1 1 2 2 2 1 AAA ATPase domain TIP49 PF06068.13 KIY66190.1 - 0.0038 16.5 0.0 0.0078 15.4 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 KIY66190.1 - 0.0056 16.7 0.0 0.021 14.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KIY66190.1 - 0.013 15.2 0.0 0.035 13.9 0.0 1.7 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KIY66190.1 - 0.015 15.6 0.5 0.3 11.3 0.1 2.8 3 1 0 3 3 2 0 AAA domain AAA_2 PF07724.14 KIY66190.1 - 0.035 14.2 0.0 0.14 12.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 KIY66190.1 - 0.036 13.8 0.1 0.12 12.1 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_17 PF13207.6 KIY66190.1 - 0.097 13.1 0.6 0.3 11.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KIY66190.1 - 0.16 11.3 0.0 0.44 9.9 0.1 1.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Dimer_Tnp_hAT PF05699.14 KIY66191.1 - 2.7e-19 68.7 0.3 3.5e-19 68.4 0.3 1.1 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RA PF00788.23 KIY66193.1 - 2.1e-10 41.1 0.0 1.2e-08 35.4 0.0 2.8 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain SH3_1 PF00018.28 KIY66193.1 - 1.1e-06 28.2 0.4 2.1e-05 24.0 0.0 2.4 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KIY66193.1 - 0.0092 15.8 0.0 0.021 14.7 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Ribosomal_60s PF00428.19 KIY66194.1 - 8e-30 103.3 11.1 9.8e-30 103.0 11.1 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF3824 PF12868.7 KIY66194.1 - 0.37 11.5 5.8 0.52 11.0 5.8 1.2 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Cytomega_UL84 PF06284.11 KIY66194.1 - 0.53 8.7 1.5 0.66 8.4 1.5 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein DUF3833 PF12915.7 KIY66195.1 - 0.24 11.0 0.0 0.4 10.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3833) zf-rbx1 PF12678.7 KIY66196.1 - 1.1e-12 48.1 3.3 1.8e-12 47.4 3.3 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KIY66196.1 - 1e-10 41.7 4.7 2.1e-10 40.7 4.7 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KIY66196.1 - 7e-08 32.2 3.5 1.2e-07 31.5 3.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KIY66196.1 - 2.5e-06 27.4 3.8 4.8e-06 26.5 3.8 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KIY66196.1 - 7.2e-06 25.7 4.2 7.2e-06 25.7 4.2 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KIY66196.1 - 1e-05 25.3 3.4 0.00037 20.3 1.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KIY66196.1 - 2.4e-05 24.3 0.4 5.1e-05 23.3 0.4 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 KIY66196.1 - 0.00012 21.9 2.9 0.00031 20.7 2.9 1.7 1 1 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KIY66196.1 - 0.00015 21.6 2.7 0.0003 20.6 2.7 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 KIY66196.1 - 0.00056 19.5 0.7 0.0013 18.3 0.7 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 KIY66196.1 - 0.0063 16.2 5.4 0.073 12.8 5.4 2.3 1 1 0 1 1 1 1 RING-like zinc finger zf-C3HC4_4 PF15227.6 KIY66196.1 - 0.0087 16.2 1.7 0.022 14.9 1.7 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 KIY66196.1 - 0.045 13.9 0.5 0.095 12.9 0.5 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.11 KIY66196.1 - 0.29 11.5 2.4 0.55 10.6 2.4 1.4 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.6 KIY66196.1 - 3 7.7 5.0 1.3 8.9 1.9 1.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Sec16_C PF12931.7 KIY66197.1 - 0.0015 18.3 0.0 0.0028 17.4 0.0 1.4 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 SRA1 PF07304.11 KIY66197.1 - 0.72 9.6 0.0 0.72 9.6 0.0 3.6 4 1 1 5 5 5 0 Steroid receptor RNA activator (SRA1) MIF PF01187.18 KIY66199.1 - 3.9e-17 62.6 0.0 4.4e-17 62.4 0.0 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Tam41_Mmp37 PF09139.11 KIY66200.1 - 8.9e-109 363.8 0.0 1e-108 363.6 0.0 1.0 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial STE3 PF02076.15 KIY66201.1 - 0.00091 18.5 0.3 0.00091 18.5 0.3 2.8 2 1 0 3 3 3 2 Pheromone A receptor DUF5336 PF17270.2 KIY66201.1 - 0.94 9.1 4.9 0.26 10.9 0.4 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5336) COPIIcoated_ERV PF07970.12 KIY66202.1 - 3.2e-36 125.3 1.0 4.7e-36 124.7 1.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 KIY66202.1 - 7.6e-21 74.3 0.0 1.3e-20 73.5 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) CBFD_NFYB_HMF PF00808.23 KIY66203.1 - 7.6e-20 71.0 1.5 1.3e-19 70.2 1.5 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KIY66203.1 - 2.6e-13 50.5 0.7 4e-13 49.9 0.7 1.5 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.10 KIY66203.1 - 0.036 14.4 0.1 0.063 13.6 0.1 1.4 1 0 0 1 1 1 0 CENP-S associating Centromere protein X CH PF00307.31 KIY66204.1 - 2.7e-73 243.1 0.0 3e-18 66.0 0.0 4.8 4 1 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KIY66204.1 - 2.6e-05 24.0 0.0 3.5 7.5 0.0 4.4 5 0 0 5 5 5 3 CAMSAP CH domain Glyco_hydro_31 PF01055.26 KIY66206.1 - 7.8e-91 305.5 5.2 1.2e-90 304.9 5.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NTP_transferase PF00483.23 KIY66207.1 - 7.8e-39 133.7 0.0 2.1e-38 132.3 0.0 1.8 2 0 0 2 2 2 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 KIY66207.1 - 5.8e-07 30.0 0.1 1.7e-06 28.5 0.1 1.7 1 1 0 1 1 1 1 MobA-like NTP transferase domain MannoseP_isomer PF01050.18 KIY66207.1 - 5.6e-05 23.1 0.1 9.5e-05 22.3 0.1 1.4 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase DUF364 PF04016.12 KIY66207.1 - 0.035 13.7 0.1 0.088 12.4 0.1 1.6 1 0 0 1 1 1 0 Putative heavy-metal chelation IspD PF01128.19 KIY66207.1 - 0.13 12.0 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase DivIC PF04977.15 KIY66207.1 - 1.5 8.7 5.5 0.28 11.0 1.9 1.6 2 0 0 2 2 2 0 Septum formation initiator Ribosomal_L4 PF00573.22 KIY66208.1 - 1.3e-38 132.6 0.9 2e-38 132.0 0.9 1.3 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 KIY66208.1 - 4.3e-29 100.4 1.3 4.3e-29 100.4 1.3 2.1 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain DUF5549 PF17703.1 KIY66208.1 - 5.9 6.5 6.2 0.49 10.0 0.6 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5549) PHD PF00628.29 KIY66209.1 - 2.1e-10 40.3 4.2 3.5e-10 39.6 4.2 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KIY66209.1 - 0.00014 21.4 2.0 0.00024 20.6 2.0 1.4 1 0 0 1 1 1 1 PHD-finger PHD_4 PF16866.5 KIY66209.1 - 0.16 12.1 4.0 0.34 11.0 4.0 1.5 1 0 0 1 1 1 0 PHD-finger tRNA-synt_His PF13393.6 KIY66211.1 - 3.5e-38 131.6 0.8 6.9e-34 117.5 0.0 2.7 3 0 0 3 3 3 2 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 KIY66211.1 - 8.7e-11 41.8 0.4 1.9e-10 40.7 0.4 1.6 1 0 0 1 1 1 1 Anticodon binding domain UPF0164 PF03687.13 KIY66211.1 - 0.03 13.1 0.1 0.049 12.4 0.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0164) Metal_resist PF13801.6 KIY66211.1 - 0.048 13.9 0.4 0.12 12.5 0.4 1.7 1 0 0 1 1 1 0 Heavy-metal resistance tRNA-synt_2 PF00152.20 KIY66211.1 - 0.1 11.7 0.0 0.29 10.2 0.0 1.8 2 0 0 2 2 2 0 tRNA synthetases class II (D, K and N) Glyco_hydro_31 PF01055.26 KIY66213.1 - 2.8e-88 297.0 1.0 4.2e-88 296.5 1.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KIY66213.1 - 0.033 14.5 0.0 0.28 11.6 0.0 2.5 2 0 0 2 2 2 0 Galactose mutarotase-like HMG_box PF00505.19 KIY66214.1 - 3.9e-16 59.2 0.3 4.4e-16 59.1 0.3 1.0 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KIY66214.1 - 1.1e-05 25.9 0.1 1.2e-05 25.8 0.1 1.1 1 0 0 1 1 1 1 HMG-box domain RRM_1 PF00076.22 KIY66215.1 - 6.1e-22 77.2 0.0 7.4e-22 77.0 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KIY66215.1 - 0.00089 19.3 0.0 0.0012 18.9 0.0 1.3 1 1 0 1 1 1 1 RNA recognition motif RRM_5 PF13893.6 KIY66215.1 - 0.081 12.5 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ABC_membrane PF00664.23 KIY66216.1 - 4.4e-36 125.0 7.9 4.4e-36 125.0 7.9 1.5 2 0 0 2 2 2 1 ABC transporter transmembrane region ABC_tran PF00005.27 KIY66216.1 - 3.3e-35 121.6 0.0 6.3e-35 120.7 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KIY66216.1 - 7.8e-05 22.2 0.3 0.0047 16.4 0.3 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KIY66216.1 - 0.00036 21.0 0.3 0.0014 19.1 0.3 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KIY66216.1 - 0.0018 18.0 0.3 0.0052 16.5 0.3 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 KIY66216.1 - 0.003 17.8 0.0 0.023 15.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KIY66216.1 - 0.011 15.6 0.0 0.03 14.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KIY66216.1 - 0.022 14.5 0.0 0.037 13.7 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain G-alpha PF00503.20 KIY66216.1 - 0.082 12.1 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit RsgA_GTPase PF03193.16 KIY66216.1 - 0.15 11.9 0.2 0.56 10.1 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase APS_kinase PF01583.20 KIY66216.1 - 0.17 11.8 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_28 PF13521.6 KIY66216.1 - 0.25 11.6 0.3 7 6.9 0.0 2.6 2 1 0 3 3 3 0 AAA domain PrgI PF12666.7 KIY66219.1 - 0.019 15.6 0.4 0.019 15.6 0.4 3.4 3 1 1 4 4 4 0 PrgI family protein LST1 PF05083.13 KIY66219.1 - 0.49 10.7 1.5 1.2 9.5 1.5 1.6 1 0 0 1 1 1 0 LST-1 protein EcsB PF05975.12 KIY66219.1 - 9.1 5.0 14.9 2.2 7.0 5.0 2.2 2 0 0 2 2 2 0 Bacterial ABC transporter protein EcsB Peroxin-13_N PF04088.13 KIY66220.1 - 2.5e-37 128.4 8.1 7e-33 113.9 8.1 2.2 1 1 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.17 KIY66220.1 - 7.1e-11 41.6 0.0 1.3e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KIY66220.1 - 7.2e-10 38.3 2.3 0.00057 19.4 0.0 2.3 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 KIY66220.1 - 2.1e-08 33.9 0.1 4e-08 33.0 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain Bestrophin PF01062.21 KIY66221.1 - 5.9e-36 124.4 1.5 4.8e-20 72.1 0.3 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel Bot1p PF12298.8 KIY66221.1 - 0.048 13.8 0.3 0.94 9.6 0.0 2.4 2 0 0 2 2 2 0 Eukaryotic mitochondrial regulator protein La PF05383.17 KIY66222.1 - 1.6e-17 63.3 0.2 3.4e-17 62.3 0.2 1.5 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 KIY66222.1 - 6.5e-09 35.5 0.0 1.6e-08 34.2 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KIY66222.1 - 0.0028 17.7 0.0 0.012 15.6 0.0 2.0 2 0 0 2 2 2 1 RNA binding motif RRM_7 PF16367.5 KIY66222.1 - 0.0035 17.4 0.0 0.0074 16.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif DarA_C PF18789.1 KIY66222.1 - 0.02 15.2 0.0 0.052 13.9 0.0 1.8 1 0 0 1 1 1 0 Defence against restriction A C-terminal API5 PF05918.11 KIY66222.1 - 2 7.1 4.0 3.2 6.5 4.0 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Joubert PF15392.6 KIY66227.1 - 0.28 10.8 4.0 0.43 10.2 4.0 1.3 1 0 0 1 1 1 0 Joubert syndrome-associated Plavaka PF18759.1 KIY66228.1 - 9.6e-31 107.2 0.1 1.9e-30 106.2 0.1 1.4 1 0 0 1 1 1 1 Plavaka transposase PH_9 PF15410.6 KIY66229.1 - 0.00077 19.8 0.0 0.0011 19.3 0.0 1.2 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KIY66229.1 - 0.099 13.2 0.0 0.13 12.7 0.0 1.2 1 0 0 1 1 1 0 PH domain Hist_deacetyl PF00850.19 KIY66231.1 - 8.8e-82 275.0 0.0 1.2e-81 274.6 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain NmrA PF05368.13 KIY66232.1 - 1.3e-26 93.6 0.2 1.6e-26 93.3 0.2 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KIY66232.1 - 1.8e-11 44.3 0.3 3.4e-10 40.1 0.3 2.2 1 1 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KIY66232.1 - 2.3e-07 31.1 0.3 4.4e-07 30.2 0.3 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KIY66232.1 - 1.7e-05 24.4 0.1 2.5e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KIY66232.1 - 0.00011 22.2 0.2 0.0002 21.3 0.2 1.3 1 0 0 1 1 1 1 KR domain Semialdhyde_dh PF01118.24 KIY66232.1 - 0.00036 21.0 0.2 0.0007 20.0 0.2 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 KIY66232.1 - 0.0005 19.3 0.0 0.00076 18.7 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 KIY66232.1 - 0.0019 17.3 0.1 0.0032 16.5 0.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Shikimate_DH PF01488.20 KIY66232.1 - 0.019 15.0 0.2 0.034 14.2 0.2 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DapB_N PF01113.20 KIY66232.1 - 0.037 14.1 0.2 0.071 13.2 0.2 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus GDP_Man_Dehyd PF16363.5 KIY66232.1 - 0.1 12.0 0.1 0.14 11.5 0.1 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase PglD_N PF17836.1 KIY66232.1 - 0.13 12.9 0.0 0.35 11.5 0.0 1.8 1 0 0 1 1 1 0 PglD N-terminal domain DUF1638 PF07796.11 KIY66232.1 - 0.14 12.2 0.0 14 5.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1638) DUF2674 PF10879.8 KIY66232.1 - 0.14 11.7 0.1 0.31 10.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2674) Glyco_hydro_76 PF03663.14 KIY66233.1 - 0.043 13.3 10.1 0.24 10.9 1.8 2.3 1 1 1 2 2 2 0 Glycosyl hydrolase family 76 Gram_pos_anchor PF00746.21 KIY66233.1 - 6.3 6.8 9.8 3 7.9 3.0 3.3 2 1 0 2 2 2 0 LPXTG cell wall anchor motif Gram_pos_anchor PF00746.21 KIY66234.1 - 1.6 8.7 6.5 0.84 9.6 3.1 2.3 2 1 0 2 2 2 0 LPXTG cell wall anchor motif AIM5 PF17050.5 KIY66235.1 - 0.35 11.7 0.2 0.35 11.7 0.2 1.9 2 0 0 2 2 2 0 Altered inheritance of mitochondria 5 RNA_pol_Rpb1_1 PF04997.12 KIY66237.1 - 9.9e-87 291.2 0.0 1.5e-86 290.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 KIY66237.1 - 7.8e-81 271.4 0.0 1.1e-80 270.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KIY66237.1 - 2.8e-72 242.3 0.0 6e-72 241.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 KIY66237.1 - 4.3e-38 130.7 0.0 1.1e-37 129.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 KIY66237.1 - 1.9e-30 105.0 0.0 4.6e-30 103.7 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 DUF1317 PF07026.11 KIY66237.1 - 0.022 14.6 0.0 0.05 13.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1317) zf-RING_7 PF02591.15 KIY66237.1 - 0.026 14.7 0.2 0.81 9.9 0.0 2.8 2 0 0 2 2 2 0 C4-type zinc ribbon domain ATG11 PF10377.9 KIY66238.1 - 1.4e-25 89.8 0.0 4.6e-25 88.2 0.0 1.9 1 0 0 1 1 1 1 Autophagy-related protein 11 ZapB PF06005.12 KIY66238.1 - 8.5e-05 22.9 37.9 0.035 14.5 1.3 6.0 4 2 1 6 6 6 3 Cell division protein ZapB IFT57 PF10498.9 KIY66238.1 - 0.00025 20.2 14.1 0.00025 20.2 14.1 2.9 1 1 1 2 2 1 1 Intra-flagellar transport protein 57 HALZ PF02183.18 KIY66238.1 - 0.00084 19.5 21.8 0.012 15.8 0.1 7.0 4 2 3 7 7 7 2 Homeobox associated leucine zipper APG17 PF04108.12 KIY66238.1 - 0.017 14.3 27.1 0.51 9.4 0.0 5.6 5 1 1 6 6 6 0 Autophagy protein Apg17 DUF1664 PF07889.12 KIY66238.1 - 0.2 11.7 21.8 0.056 13.5 1.2 4.9 3 1 2 6 6 6 0 Protein of unknown function (DUF1664) Scaffolding_pro PF11418.8 KIY66238.1 - 1.6 9.3 4.3 22 5.7 0.2 3.0 2 0 0 2 2 2 0 Phi29 scaffolding protein YabA PF06156.13 KIY66238.1 - 1.7 9.3 28.9 0.85 10.3 0.6 5.0 4 1 1 5 5 5 0 Initiation control protein YabA Phage_GP20 PF06810.11 KIY66238.1 - 2.3 8.0 21.6 1.2 8.9 1.4 3.8 2 1 1 3 3 3 0 Phage minor structural protein GP20 SHE3 PF17078.5 KIY66238.1 - 2.5 7.8 24.0 0.3 10.8 4.1 3.2 2 2 1 3 3 3 0 SWI5-dependent HO expression protein 3 Spc7 PF08317.11 KIY66238.1 - 2.5 6.9 43.5 0.14 11.0 3.2 3.7 1 1 3 4 4 3 0 Spc7 kinetochore protein Bacillus_HBL PF05791.11 KIY66238.1 - 7.6 6.3 7.7 22 4.8 1.0 2.5 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF2156 PF09924.9 KIY66240.1 - 1.5e-16 60.3 0.0 2.1e-16 59.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) SMC_ScpB PF04079.16 KIY66240.1 - 0.14 11.8 0.0 0.38 10.3 0.0 1.7 2 0 0 2 2 2 0 Segregation and condensation complex subunit ScpB PDEase_II PF02112.15 KIY66241.1 - 2.5e-43 148.5 0.0 2.3e-42 145.3 0.0 2.1 1 1 0 1 1 1 1 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.7 KIY66241.1 - 0.0009 18.8 0.1 0.0017 17.9 0.1 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain FB_lectin PF07367.11 KIY66243.1 - 5.4e-59 198.1 0.5 6e-59 198.0 0.5 1.0 1 0 0 1 1 1 1 Fungal fruit body lectin DUF2156 PF09924.9 KIY66246.1 - 4.1e-15 55.6 0.0 5.4e-15 55.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) Abhydrolase_3 PF07859.13 KIY66247.1 - 8e-20 71.6 0.0 1.5e-17 64.2 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KIY66247.1 - 1.4e-06 27.4 0.0 2.6e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Steryl acetyl hydrolase Hydrolase_4 PF12146.8 KIY66247.1 - 4.5e-05 22.8 0.0 8.4e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PigN PF04987.14 KIY66248.1 - 5.4e-123 411.2 38.2 6.7e-123 410.9 38.2 1.1 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 KIY66248.1 - 6.5e-10 39.1 0.8 1.3e-07 31.6 0.4 2.3 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KIY66248.1 - 2.1e-06 27.4 0.1 3.3e-06 26.7 0.1 1.3 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 KIY66248.1 - 0.0036 16.7 0.1 0.0059 16.0 0.1 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily DUF2516 PF10724.9 KIY66248.1 - 6.6 7.1 7.7 15 5.9 0.1 3.8 2 2 1 3 3 3 0 Protein of unknown function (DUF2516) DJ-1_PfpI PF01965.24 KIY66249.1 - 7e-16 58.5 0.0 1.2e-15 57.7 0.0 1.4 1 1 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI PF01965.24 KIY66250.1 - 9.8e-13 48.2 0.0 1.3e-12 47.8 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family DUF2156 PF09924.9 KIY66251.1 - 9.2e-16 57.7 0.0 1.4e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) SMC_ScpB PF04079.16 KIY66251.1 - 0.16 11.6 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 Segregation and condensation complex subunit ScpB KH_8 PF17903.1 KIY66252.1 - 2.7e-32 110.7 0.1 1.3e-31 108.5 0.0 2.1 2 0 0 2 2 2 1 Krr1 KH1 domain KH_1 PF00013.29 KIY66252.1 - 0.0011 18.8 0.0 0.0021 17.8 0.0 1.5 1 0 0 1 1 1 1 KH domain KH_4 PF13083.6 KIY66252.1 - 0.041 13.8 0.0 0.094 12.6 0.0 1.6 1 0 0 1 1 1 0 KH domain TRAP_alpha PF03896.16 KIY66253.1 - 0.07 12.3 0.0 0.1 11.8 0.0 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Endonuclease_NS PF01223.23 KIY66255.1 - 1.9e-55 188.1 0.0 2.5e-55 187.8 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease zf-C2H2_4 PF13894.6 KIY66256.1 - 0.013 16.2 3.7 0.5 11.3 0.2 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KIY66256.1 - 0.088 13.3 0.2 0.088 13.3 0.2 3.7 4 1 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KIY66256.1 - 0.47 10.8 0.2 0.47 10.8 0.2 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding HMG_box PF00505.19 KIY66257.1 - 1e-17 64.3 3.9 2.3e-17 63.1 3.9 1.5 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KIY66257.1 - 3.4e-12 46.8 1.3 4.1e-12 46.5 1.3 1.1 1 0 0 1 1 1 1 HMG-box domain MATalpha_HMGbox PF04769.12 KIY66257.1 - 0.022 14.1 0.0 0.024 13.9 0.0 1.1 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 HMG-box DUF2805 PF10985.8 KIY66257.1 - 0.029 14.8 0.6 0.042 14.2 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2805) HMG_box PF00505.19 KIY66258.1 - 0.029 14.8 0.5 0.058 13.8 0.1 1.7 2 0 0 2 2 2 0 HMG (high mobility group) box HPS3_Mid PF14762.6 KIY66258.1 - 0.087 11.6 0.1 0.11 11.2 0.1 1.1 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 3, middle region V-ATPase_H_N PF03224.14 KIY66259.1 - 3e-83 279.7 4.2 3e-83 279.7 4.2 1.6 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 KIY66259.1 - 4.9e-42 142.8 2.5 1.1e-41 141.6 0.1 2.6 3 0 0 3 3 3 1 V-ATPase subunit H HEAT PF02985.22 KIY66259.1 - 2.6e-05 24.1 3.2 0.11 12.9 0.0 5.0 6 0 0 6 6 6 1 HEAT repeat HEAT_2 PF13646.6 KIY66259.1 - 0.00013 22.3 0.6 0.4 11.1 0.1 3.9 3 1 0 3 3 3 1 HEAT repeats Arm_2 PF04826.13 KIY66259.1 - 0.00069 19.1 0.1 0.066 12.7 0.0 2.4 2 0 0 2 2 2 1 Armadillo-like Arm PF00514.23 KIY66259.1 - 0.0025 17.8 0.1 0.58 10.3 0.0 3.9 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat Uso1_p115_head PF04869.14 KIY66259.1 - 0.0061 15.7 0.7 0.0094 15.1 0.7 1.3 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region DUF4042 PF13251.6 KIY66259.1 - 0.074 12.7 0.3 0.31 10.7 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4042) DUF974 PF06159.13 KIY66260.1 - 4.6e-76 255.9 0.0 6e-76 255.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF974) DUF3640 PF12342.8 KIY66260.1 - 0.041 13.6 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3640) Esterase_phd PF10503.9 KIY66261.1 - 0.0085 15.6 0.2 0.013 15.0 0.2 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase Esterase PF00756.20 KIY66261.1 - 0.022 14.4 0.1 0.036 13.7 0.1 1.3 1 0 0 1 1 1 0 Putative esterase Peptidase_S9 PF00326.21 KIY66261.1 - 0.095 12.2 0.6 2.1 7.8 0.5 2.3 1 1 1 2 2 2 0 Prolyl oligopeptidase family Esterase_phd PF10503.9 KIY66262.1 - 0.00015 21.4 0.7 0.00028 20.5 0.7 1.5 1 1 0 1 1 1 1 Esterase PHB depolymerase Esterase PF00756.20 KIY66262.1 - 0.0073 16.0 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 KIY66262.1 - 0.11 12.0 0.4 0.26 10.7 0.4 1.7 2 1 0 2 2 2 0 Prolyl oligopeptidase family MRP-L46 PF11788.8 KIY66263.1 - 1e-14 55.3 0.1 2.2e-14 54.2 0.1 1.6 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.28 KIY66263.1 - 0.00035 20.6 0.0 0.00085 19.4 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain DNA_pol_B PF00136.21 KIY66264.1 - 1.7e-97 327.0 0.0 2.3e-97 326.6 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 KIY66264.1 - 1.1e-22 80.7 0.0 7.2e-11 41.8 0.0 2.2 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 KIY66264.1 - 9e-14 51.7 6.1 2.1e-13 50.5 6.1 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 KIY66264.1 - 0.15 10.9 0.0 0.24 10.2 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral AGTRAP PF06396.11 KIY66265.1 - 0.031 14.1 0.2 0.066 13.0 0.2 1.6 1 1 0 1 1 1 0 Angiotensin II, type I receptor-associated protein (AGTRAP) GPI-anchored PF10342.9 KIY66266.1 - 0.05 14.4 0.2 0.083 13.7 0.2 1.4 1 1 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family GPI-anchored PF10342.9 KIY66267.1 - 4.3e-07 30.6 0.1 6.8e-07 30.0 0.1 1.4 1 1 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Flocculin PF00624.18 KIY66267.1 - 0.077 13.3 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 Flocculin repeat Cwf_Cwc_15 PF04889.12 KIY66268.1 - 4.5e-84 282.0 24.0 5.1e-84 281.9 24.0 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein MFAP1 PF06991.11 KIY66268.1 - 0.016 15.1 21.9 0.029 14.2 21.9 1.5 1 0 0 1 1 1 0 Microfibril-associated/Pre-mRNA processing Nop14 PF04147.12 KIY66268.1 - 0.21 9.7 21.4 0.26 9.5 21.4 1.1 1 0 0 1 1 1 0 Nop14-like family TFIIF_alpha PF05793.12 KIY66268.1 - 0.31 9.6 22.5 0.42 9.2 22.5 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC27 PF09507.10 KIY66268.1 - 0.72 9.2 20.1 0.95 8.8 20.1 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 BBS2_C PF14782.6 KIY66268.1 - 3.9 6.1 7.1 1.1 7.9 0.9 2.0 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, C-terminal Tetraspanin PF00335.20 KIY66269.1 - 2.3e-05 24.2 15.5 3.7e-05 23.6 15.5 1.3 1 1 0 1 1 1 1 Tetraspanin family DUF4191 PF13829.6 KIY66269.1 - 0.86 8.9 0.0 0.86 8.9 0.0 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4191) Gram_pos_anchor PF00746.21 KIY66269.1 - 1.2 9.2 7.7 1.2 9.1 0.0 3.4 4 0 0 4 4 4 0 LPXTG cell wall anchor motif SieB PF14163.6 KIY66269.1 - 5.6 6.5 8.6 2.1 7.8 1.3 2.8 2 1 1 3 3 3 0 Super-infection exclusion protein B Ribosomal_L14 PF00238.19 KIY66270.1 - 2.3e-34 118.1 0.0 3e-34 117.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Bmt2 PF11968.8 KIY66271.1 - 5.1e-59 199.8 0.0 6.9e-59 199.4 0.0 1.1 1 0 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Methyltransf_23 PF13489.6 KIY66271.1 - 0.00026 20.9 0.0 0.00067 19.5 0.0 1.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIY66271.1 - 0.0012 19.6 0.0 0.0044 17.7 0.0 2.0 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIY66271.1 - 0.0015 19.1 0.0 0.012 16.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain NodS PF05401.11 KIY66271.1 - 0.087 12.4 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) Ribosomal_S2 PF00318.20 KIY66275.1 - 1.5e-53 181.3 0.0 1.3e-29 103.0 0.0 2.2 1 1 1 2 2 2 2 Ribosomal protein S2 HSP70 PF00012.20 KIY66276.1 - 3.3e-237 788.5 4.6 4.1e-237 788.2 4.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KIY66276.1 - 3.1e-15 55.8 0.1 3.4e-14 52.4 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein BcrAD_BadFG PF01869.20 KIY66276.1 - 0.0075 15.8 0.1 1.9 7.9 0.0 2.5 2 1 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family FGGY_C PF02782.16 KIY66276.1 - 0.011 15.5 0.0 0.025 14.3 0.0 1.6 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.10 KIY66276.1 - 0.026 13.5 0.4 0.21 10.5 0.1 2.2 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain DUF1539 PF07560.11 KIY66276.1 - 0.061 13.4 0.0 2.4 8.2 0.0 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1539) CRM1_C PF08767.11 KIY66278.1 - 7.3e-127 423.0 0.5 3.3e-125 417.5 0.0 3.0 2 1 1 3 3 3 1 CRM1 C terminal Xpo1 PF08389.12 KIY66278.1 - 1.2e-40 139.1 6.7 1e-39 136.0 6.7 2.8 2 0 0 2 2 2 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 KIY66278.1 - 2.4e-33 113.6 4.2 7.3e-33 112.0 4.2 1.9 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 KIY66278.1 - 2.7e-30 104.2 1.4 2.7e-30 104.2 1.4 2.7 2 0 0 2 2 2 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 KIY66278.1 - 2.6e-19 68.4 2.9 2.6e-19 68.4 2.9 2.6 2 0 0 2 2 2 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 KIY66278.1 - 2e-12 46.8 0.0 8.7e-12 44.8 0.0 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain Symplekin_C PF12295.8 KIY66278.1 - 0.023 14.8 0.2 3.7 7.6 0.0 3.0 2 0 0 2 2 2 0 Symplekin tight junction protein C terminal Calsequestrin PF01216.17 KIY66279.1 - 0.096 11.7 0.1 0.11 11.5 0.1 1.1 1 0 0 1 1 1 0 Calsequestrin Spc24 PF08286.11 KIY66280.1 - 1.6e-08 34.7 0.1 1.6e-08 34.7 0.1 2.2 1 1 1 2 2 2 1 Spc24 subunit of Ndc80 Tweety PF04906.13 KIY66280.1 - 0.12 11.0 1.1 0.34 9.5 0.9 1.9 2 0 0 2 2 2 0 Tweety BAR_2 PF10455.9 KIY66280.1 - 0.14 11.3 6.2 0.19 10.8 6.2 1.2 1 0 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking DUF2203 PF09969.9 KIY66280.1 - 0.35 11.6 6.3 0.52 11.0 4.1 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF4072 PF13284.6 KIY66280.1 - 0.44 11.0 3.4 12 6.4 0.1 3.8 3 1 1 4 4 4 0 Domain of unknown function (DUF4072) Phage_GPO PF05929.11 KIY66280.1 - 0.46 10.1 9.5 0.76 9.3 9.5 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Baculo_p24 PF05073.12 KIY66280.1 - 0.56 10.0 3.3 0.84 9.4 3.1 1.4 1 1 0 1 1 1 0 Baculovirus P24 capsid protein DUF1818 PF08848.11 KIY66280.1 - 0.76 9.9 3.5 0.76 9.9 0.8 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF1818) Cortex-I_coil PF09304.10 KIY66280.1 - 1.2 9.4 12.9 0.72 10.1 4.5 2.4 1 1 1 2 2 2 0 Cortexillin I, coiled coil AAA PF00004.29 KIY66281.1 - 6.4e-15 55.7 0.0 1.4e-14 54.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 KIY66281.1 - 2.9e-12 46.7 0.0 1.5e-10 41.1 0.0 2.3 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.11 KIY66281.1 - 1.2e-10 41.6 0.0 3.4e-10 40.2 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain Rad17 PF03215.15 KIY66281.1 - 2.3e-08 34.2 0.0 5.1e-08 33.1 0.0 1.6 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_assoc_2 PF16193.5 KIY66281.1 - 1.7e-06 28.3 0.0 5e-06 26.8 0.0 1.8 1 0 0 1 1 1 1 AAA C-terminal domain AAA_22 PF13401.6 KIY66281.1 - 1.8e-05 25.1 0.0 0.0003 21.1 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KIY66281.1 - 5e-05 23.8 0.1 0.00029 21.2 0.1 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 KIY66281.1 - 0.00014 21.9 0.0 0.00041 20.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 KIY66281.1 - 0.00018 21.4 0.0 0.0003 20.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KIY66281.1 - 0.00033 20.4 0.0 0.00095 18.9 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 KIY66281.1 - 0.0024 17.6 0.0 0.005 16.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KIY66281.1 - 0.0036 16.7 0.0 0.082 12.3 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 KIY66281.1 - 0.0039 16.9 0.0 0.01 15.6 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KIY66281.1 - 0.0042 16.6 0.0 0.0075 15.8 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_2 PF07724.14 KIY66281.1 - 0.0081 16.3 0.0 0.015 15.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) ResIII PF04851.15 KIY66281.1 - 0.0088 16.1 0.0 0.048 13.7 0.0 2.0 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KIY66281.1 - 0.021 14.6 0.2 0.39 10.5 0.0 2.8 2 1 1 4 4 4 0 DEAD/DEAH box helicase AAA_19 PF13245.6 KIY66281.1 - 0.024 15.0 0.0 0.15 12.4 0.0 2.1 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.13 KIY66281.1 - 0.034 13.3 0.0 0.05 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DUF2075 PF09848.9 KIY66281.1 - 0.047 12.9 0.0 0.091 12.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_28 PF13521.6 KIY66281.1 - 0.057 13.7 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KIY66281.1 - 0.059 13.9 0.0 0.14 12.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain DNA_pol3_delta PF06144.13 KIY66281.1 - 0.059 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase III, delta subunit CAF1A PF12253.8 KIY66282.1 - 2e-20 72.7 5.9 5.2e-20 71.4 5.9 1.8 1 0 0 1 1 1 1 Chromatin assembly factor 1 subunit A SAC3_GANP PF03399.16 KIY66283.1 - 9.5e-14 51.5 0.3 5.8e-13 48.9 0.3 2.0 1 1 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 KIY66283.1 - 0.00041 20.3 0.0 0.0037 17.2 0.0 2.5 2 1 0 2 2 2 1 CSN8/PSMD8/EIF3K family DUF4777 PF16007.5 KIY66283.1 - 0.13 12.5 0.0 0.32 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4777) HMG_box PF00505.19 KIY66284.1 - 5.4e-15 55.6 0.2 1.1e-14 54.6 0.2 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KIY66284.1 - 0.0051 17.4 0.3 0.014 16.0 0.3 1.7 1 0 0 1 1 1 1 HMG-box domain Cpn60_TCP1 PF00118.24 KIY66285.1 - 1.6e-145 485.5 12.8 1.9e-145 485.3 12.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Sua5_yciO_yrdC PF01300.18 KIY66285.1 - 0.0034 16.9 0.0 0.008 15.7 0.0 1.6 1 0 0 1 1 1 1 Telomere recombination TPR_2 PF07719.17 KIY66286.1 - 1.1e-27 93.8 11.8 0.0085 16.1 0.1 9.6 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_1 PF00515.28 KIY66286.1 - 2.3e-23 81.0 11.7 0.0002 21.0 0.1 7.8 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_19 PF14559.6 KIY66286.1 - 2.2e-17 63.3 11.1 0.00022 21.7 0.0 7.7 7 1 1 8 8 7 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KIY66286.1 - 8.9e-17 61.1 14.6 8e-12 45.2 0.8 4.8 4 1 0 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 KIY66286.1 - 6.9e-16 57.1 6.3 0.53 10.6 0.0 7.9 8 0 0 8 8 7 5 Tetratricopeptide repeat TPR_14 PF13428.6 KIY66286.1 - 1.2e-15 56.9 11.8 0.0037 17.9 0.1 9.8 5 2 4 9 9 9 3 Tetratricopeptide repeat TPR_11 PF13414.6 KIY66286.1 - 1.3e-13 50.4 0.7 0.021 14.5 0.0 7.3 6 2 3 9 9 9 3 TPR repeat TPR_17 PF13431.6 KIY66286.1 - 2.8e-13 49.2 3.0 0.1 13.0 0.0 7.5 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 KIY66286.1 - 1.6e-12 47.8 13.7 0.00038 21.1 0.1 7.4 6 1 0 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.6 KIY66286.1 - 2.3e-08 34.2 15.1 0.13 12.6 0.8 8.4 5 2 3 9 9 9 2 Tetratricopeptide repeat TPR_7 PF13176.6 KIY66286.1 - 2.5e-08 33.3 9.4 2 8.6 0.1 8.9 10 1 0 10 10 9 2 Tetratricopeptide repeat TPR_9 PF13371.6 KIY66286.1 - 3.4e-08 33.5 5.6 0.00023 21.2 0.1 4.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 KIY66286.1 - 2.9e-07 30.7 7.3 6.8 7.6 0.0 8.5 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_15 PF13429.6 KIY66286.1 - 0.012 14.9 12.8 1.3 8.2 0.0 4.8 4 1 1 5 5 5 0 Tetratricopeptide repeat PPTA PF01239.22 KIY66286.1 - 0.11 12.3 0.1 0.4 10.5 0.1 2.0 1 0 0 1 1 1 0 Protein prenyltransferase alpha subunit repeat TPR_10 PF13374.6 KIY66286.1 - 0.5 10.3 4.8 7.1 6.6 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat SOG2 PF10428.9 KIY66286.1 - 5.8 6.0 11.2 8.9 5.4 11.2 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein SRR1 PF07985.12 KIY66288.1 - 6.3e-14 51.8 0.0 1.1e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 SRR1 Pre-PUA PF17832.1 KIY66289.1 - 2.2e-24 85.9 0.1 3.4e-24 85.3 0.1 1.3 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 KIY66289.1 - 2.8e-15 56.1 0.1 7.7e-15 54.6 0.1 1.7 1 1 0 1 1 1 1 PUA domain DUF1947 PF09183.10 KIY66289.1 - 0.028 14.7 0.1 0.058 13.7 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1947) RhgB_N PF09284.10 KIY66290.1 - 7.7e-101 336.8 2.7 1.1e-100 336.4 2.7 1.2 1 0 0 1 1 1 1 Rhamnogalacturonan lyase B, N-terminal CBM-like PF14683.6 KIY66290.1 - 5.1e-37 127.3 0.0 1.4e-36 125.8 0.0 1.8 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.6 KIY66290.1 - 4.1e-20 71.3 2.1 1.1e-19 69.9 2.1 1.8 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.6 KIY66290.1 - 0.00017 21.8 0.8 0.00061 20.0 0.8 1.9 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 KIY66290.1 - 0.029 14.4 0.3 0.17 11.9 0.1 2.1 2 0 0 2 2 2 0 CarboxypepD_reg-like domain EI24 PF07264.11 KIY66291.1 - 6.1e-32 111.3 14.7 8e-32 110.9 14.7 1.1 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) DUF2254 PF10011.9 KIY66291.1 - 0.51 9.1 4.4 0.8 8.5 4.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) Lipase_GDSL_2 PF13472.6 KIY66292.1 - 1.5e-27 97.1 0.1 2.9e-27 96.2 0.1 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KIY66292.1 - 6.8e-19 68.6 0.0 9.3e-19 68.2 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase UQ_con PF00179.26 KIY66293.1 - 2.4e-40 137.4 0.2 2.7e-40 137.3 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KIY66293.1 - 0.003 17.3 0.0 0.0036 17.0 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KIY66293.1 - 0.053 13.8 0.1 0.061 13.6 0.1 1.3 1 0 0 1 1 1 0 RWD domain SPRY PF00622.28 KIY66294.1 - 2.1e-11 44.0 0.0 2.1e-08 34.3 0.0 2.5 2 0 0 2 2 2 2 SPRY domain RPAP3_C PF13877.6 KIY66296.1 - 5.9e-17 62.0 0.1 1.6e-16 60.6 0.0 1.6 2 0 0 2 2 2 1 Potential Monad-binding region of RPAP3 TPR_1 PF00515.28 KIY66296.1 - 1.6e-12 46.6 0.3 8e-07 28.6 0.3 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KIY66296.1 - 1.2e-10 40.6 1.7 0.001 19.0 0.2 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 KIY66296.1 - 7e-08 32.0 0.0 0.013 15.2 0.0 2.3 2 0 0 2 2 2 2 TPR repeat TPR_16 PF13432.6 KIY66296.1 - 3.2e-06 27.7 6.6 0.00013 22.5 2.6 2.8 3 1 1 4 4 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 KIY66296.1 - 1.1e-05 25.5 0.4 0.002 18.4 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KIY66296.1 - 1.7e-05 25.2 0.1 0.022 15.3 0.0 2.6 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 KIY66296.1 - 5.8e-05 23.2 0.3 0.0077 16.4 0.2 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KIY66296.1 - 0.00018 21.3 0.8 0.18 11.9 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 KIY66296.1 - 0.00027 20.9 0.3 0.24 11.7 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 KIY66296.1 - 0.0009 19.5 1.1 0.02 15.1 0.7 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KIY66296.1 - 0.0013 18.8 0.1 0.0032 17.5 0.1 1.6 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.6 KIY66296.1 - 0.0063 17.2 1.2 0.48 11.4 0.2 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 KIY66296.1 - 0.029 15.0 0.4 40 5.1 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KIY66296.1 - 0.13 12.5 0.1 3.4 8.0 0.0 2.4 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 PilN_bio_d PF18222.1 KIY66296.1 - 0.13 12.7 0.0 0.2 12.1 0.0 1.3 1 0 0 1 1 1 0 PilN biogenesis protein dimerization domain Linker_histone PF00538.19 KIY66297.1 - 9.9e-23 80.3 2.1 3.8e-22 78.4 0.0 2.8 2 1 0 3 3 3 1 linker histone H1 and H5 family RF-1 PF00472.20 KIY66298.1 - 3.5e-23 81.7 5.6 3.5e-23 81.7 5.6 2.2 2 1 1 3 3 3 1 RF-1 domain DUF2250 PF10007.9 KIY66298.1 - 0.15 12.2 2.3 0.3 11.2 2.3 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) TMEM214 PF10151.9 KIY66298.1 - 0.18 10.2 6.3 0.26 9.7 6.3 1.2 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator U1snRNP70_N PF12220.8 KIY66298.1 - 0.73 10.5 10.7 0.81 10.4 5.5 2.5 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal B277 PF17623.2 KIY66298.1 - 7.5 5.5 7.5 11 4.9 7.5 1.2 1 0 0 1 1 1 0 Domain of unknown function CAP_N PF01213.19 KIY66299.1 - 2.2e-99 332.9 0.1 2.9e-99 332.6 0.1 1.1 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 KIY66299.1 - 2e-58 196.5 2.5 2.6e-58 196.1 2.5 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 KIY66299.1 - 0.036 13.8 4.6 0.071 12.9 4.6 1.5 1 1 0 1 1 1 0 Tubulin binding cofactor C DEC-1_N PF04625.13 KIY66299.1 - 1.6 7.6 29.5 0.24 10.4 4.0 2.3 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region ATP12 PF07542.11 KIY66301.1 - 4.8e-42 143.1 1.1 6e-42 142.8 0.3 1.6 2 0 0 2 2 2 1 ATP12 chaperone protein Nt_Gln_amidase PF09764.9 KIY66302.1 - 3.3e-53 180.1 0.3 3.8e-53 179.8 0.3 1.0 1 0 0 1 1 1 1 N-terminal glutamine amidase RHD_dimer PF16179.5 KIY66302.1 - 0.11 12.5 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 Rel homology dimerisation domain BTB PF00651.31 KIY66303.1 - 1.1e-05 25.6 0.0 1.9e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KIY66305.1 - 0.00029 21.0 0.0 0.0011 19.2 0.0 1.9 1 1 1 2 2 2 1 BTB/POZ domain Malic_M PF03949.15 KIY66306.1 - 2.5e-88 295.7 0.0 3.4e-88 295.3 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 KIY66306.1 - 2.8e-69 232.6 0.0 4.3e-69 232.0 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain VitK2_biosynth PF02621.14 KIY66306.1 - 0.032 13.8 0.0 0.067 12.7 0.0 1.5 1 0 0 1 1 1 0 Menaquinone biosynthesis NYN PF01936.18 KIY66307.1 - 1.4e-14 54.8 0.0 2.2e-14 54.2 0.0 1.3 1 0 0 1 1 1 1 NYN domain NYN PF01936.18 KIY66308.1 - 1.5e-15 57.9 0.0 2.2e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 NYN domain PRIMA1 PF16101.5 KIY66308.1 - 2.9 8.0 8.4 3.1 7.9 6.9 1.8 1 1 0 1 1 1 0 Proline-rich membrane anchor 1 adh_short_C2 PF13561.6 KIY66309.1 - 1.6e-51 175.2 3.6 7.4e-50 169.7 3.6 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIY66309.1 - 8.8e-46 155.8 1.0 1.1e-45 155.6 1.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIY66309.1 - 1e-12 48.3 0.1 1.6e-12 47.7 0.1 1.3 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KIY66309.1 - 0.0014 18.5 0.3 0.0023 17.9 0.3 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 KIY66309.1 - 0.01 16.5 0.1 0.029 15.1 0.0 1.8 1 1 1 2 2 2 0 Methyltransferase domain UDPG_MGDP_dh_N PF03721.14 KIY66309.1 - 0.12 11.9 0.1 0.23 11.0 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ESP PF16590.5 KIY66310.1 - 0.03 14.6 0.0 0.062 13.6 0.0 1.6 1 0 0 1 1 1 0 Exocrine gland-secreting peptide NP1-WLL PF11733.8 KIY66310.1 - 0.3 10.8 3.3 0.43 10.3 3.3 1.1 1 0 0 1 1 1 0 Non-capsid protein NP1 Pkinase_fungal PF17667.1 KIY66311.1 - 3.5e-07 29.3 0.0 4.2e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Abhydrolase_6 PF12697.7 KIY66312.1 - 2.4e-14 54.5 1.8 7.4e-14 52.9 1.8 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KIY66312.1 - 2.7e-14 53.4 0.1 5.3e-14 52.5 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIY66312.1 - 2.5e-05 23.7 0.0 4e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 KIY66312.1 - 0.024 13.3 0.0 0.049 12.3 0.0 1.5 1 0 0 1 1 1 0 Ndr family Kelch_4 PF13418.6 KIY66314.1 - 0.0053 16.7 5.1 3.8 7.6 0.1 4.1 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_3 PF13415.6 KIY66314.1 - 0.43 10.9 0.0 0.43 10.9 0.0 3.5 4 0 0 4 4 4 0 Galactose oxidase, central domain COesterase PF00135.28 KIY66315.1 - 7.1e-65 219.8 0.0 8.7e-65 219.5 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KIY66315.1 - 1.7e-14 54.2 0.1 2.8e-14 53.5 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold NUDIX PF00293.28 KIY66316.1 - 3.3e-09 36.9 0.0 5.4e-08 32.9 0.0 2.2 1 1 0 1 1 1 1 NUDIX domain NIF PF03031.18 KIY66317.1 - 1.7e-21 76.6 0.0 3.4e-21 75.6 0.0 1.5 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase ubiquitin PF00240.23 KIY66317.1 - 6.2e-07 29.1 0.0 1.2e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family F-box PF00646.33 KIY66318.1 - 0.0014 18.4 0.4 0.0034 17.2 0.4 1.6 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KIY66318.1 - 0.0048 16.8 0.1 0.0087 15.9 0.1 1.4 1 0 0 1 1 1 1 F-box F-box-like PF12937.7 KIY66318.1 - 0.047 13.6 0.1 0.08 12.8 0.1 1.4 1 0 0 1 1 1 0 F-box-like Sld7_C PF18596.1 KIY66319.1 - 3.7e-06 27.0 0.2 1e-05 25.6 0.2 1.7 1 1 0 1 1 1 1 Sld7 C-terminal domain YIF1 PF03878.15 KIY66320.1 - 1.3e-85 286.7 0.5 1.7e-85 286.4 0.5 1.1 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.17 KIY66320.1 - 2.8e-05 23.9 3.5 4.5e-05 23.2 3.5 1.3 1 0 0 1 1 1 1 Yip1 domain YwiC PF14256.6 KIY66320.1 - 0.2 12.0 7.4 0.59 10.5 7.4 1.8 1 1 0 1 1 1 0 YwiC-like protein Pyr_redox_2 PF07992.14 KIY66321.1 - 1.2e-43 149.5 0.0 1.8e-43 148.9 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.32 KIY66321.1 - 1.2e-11 43.3 1.5 4.3e-06 25.9 0.3 2.4 2 0 0 2 2 2 2 EF hand Pyr_redox PF00070.27 KIY66321.1 - 2.7e-10 40.6 0.5 9e-07 29.4 0.0 3.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase EF-hand_7 PF13499.6 KIY66321.1 - 1.8e-09 37.9 3.2 1.7e-07 31.6 0.8 1.9 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KIY66321.1 - 7.1e-09 34.9 0.2 0.003 17.4 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 KIY66321.1 - 8.6e-08 31.3 0.7 0.00059 19.2 0.1 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 KIY66321.1 - 8.6e-05 22.3 0.4 0.15 12.0 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair Pyr_redox_3 PF13738.6 KIY66321.1 - 0.012 14.9 2.2 1.1 8.4 1.7 2.9 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase EF-hand_4 PF12763.7 KIY66321.1 - 0.06 13.3 1.0 1.4 8.9 0.1 2.3 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand Death_2 PF14786.6 KIY66321.1 - 0.068 13.1 0.1 0.16 11.9 0.1 1.6 1 0 0 1 1 1 0 Tube Death domain DUF16 PF01519.16 KIY66321.1 - 0.1 13.1 0.8 0.23 12.0 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF16 SPARC_Ca_bdg PF10591.9 KIY66321.1 - 0.11 12.9 0.3 5 7.5 0.0 2.4 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region NAD_binding_7 PF13241.6 KIY66321.1 - 0.12 12.8 0.0 0.87 10.1 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding SPX PF03105.19 KIY66322.1 - 1.6e-34 120.5 8.2 4.9e-24 86.0 1.3 2.1 1 1 1 2 2 2 2 SPX domain CitMHS PF03600.16 KIY66322.1 - 6.6e-29 101.1 42.5 3.2e-26 92.3 22.8 2.2 1 1 1 2 2 2 2 Citrate transporter Na_sulph_symp PF00939.19 KIY66322.1 - 9.6e-29 100.7 27.3 1.4e-28 100.2 27.3 1.2 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CDC45 PF02724.14 KIY66322.1 - 0.21 9.9 1.7 0.29 9.4 1.7 1.1 1 0 0 1 1 1 0 CDC45-like protein F-box-like PF12937.7 KIY66323.1 - 3.9e-06 26.7 0.7 1e-05 25.3 0.2 2.1 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 KIY66323.1 - 5e-05 23.1 0.0 0.00017 21.4 0.0 1.9 2 0 0 2 2 2 1 F-box domain CMAS PF02353.20 KIY66324.1 - 2.9e-65 220.3 0.2 3.6e-65 220.0 0.2 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 KIY66324.1 - 1.8e-15 57.3 0.0 1.1e-14 54.8 0.0 2.4 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIY66324.1 - 2.1e-14 54.0 0.2 7.1e-14 52.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIY66324.1 - 1.6e-10 41.1 0.0 2.7e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIY66324.1 - 4.5e-08 33.8 0.0 1.6e-07 32.0 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIY66324.1 - 2.8e-07 30.5 0.0 5.4e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 KIY66324.1 - 4.7e-06 26.3 0.0 2e-05 24.3 0.0 1.8 2 0 0 2 2 2 1 Histone methylation protein DOT1 MTS PF05175.14 KIY66324.1 - 0.002 17.7 0.0 0.0033 17.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 KIY66324.1 - 0.0055 16.5 0.0 0.0092 15.8 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 KIY66324.1 - 0.008 15.6 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltr_RsmB-F PF01189.17 KIY66324.1 - 0.0082 15.8 0.0 0.024 14.3 0.0 1.7 2 0 0 2 2 2 1 16S rRNA methyltransferase RsmB/F MetW PF07021.12 KIY66324.1 - 0.045 13.4 0.0 0.099 12.2 0.0 1.6 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Coatomer_WDAD PF04053.14 KIY66325.1 - 9.1e-146 486.4 0.0 7.3e-145 483.4 0.0 1.9 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 KIY66325.1 - 1.4e-35 120.7 9.6 4.7e-07 30.4 0.0 8.5 9 0 0 9 9 9 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY66325.1 - 1.5e-08 34.8 0.1 0.0061 16.8 0.0 5.9 4 2 3 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIY66325.1 - 5.9e-05 21.9 0.6 0.039 12.6 0.1 3.2 2 1 2 4 4 4 2 Nucleoporin Nup120/160 Peptidase_M50 PF02163.22 KIY66327.1 - 2.6e-08 33.4 4.3 5.4e-05 22.6 0.2 2.7 2 1 0 2 2 2 2 Peptidase family M50 DUF2877 PF11392.8 KIY66327.1 - 0.087 13.5 0.0 0.17 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2877) Rab5ip PF07019.12 KIY66327.1 - 0.3 11.7 6.4 0.095 13.3 0.6 2.5 2 0 0 2 2 2 0 Rab5-interacting protein (Rab5ip) WD40 PF00400.32 KIY66328.1 - 4.4e-19 68.5 4.0 2.2e-05 25.1 0.2 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY66328.1 - 0.00083 19.6 0.1 12 6.3 0.0 4.7 2 2 4 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIY66328.1 - 0.0012 18.7 0.0 1.6 8.6 0.0 3.2 3 2 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 KIY66328.1 - 0.07 11.7 0.1 2 6.8 0.0 2.6 1 1 1 2 2 2 0 Cytochrome D1 heme domain IKI3 PF04762.12 KIY66328.1 - 0.11 10.4 0.0 2.8 5.8 0.0 2.2 2 0 0 2 2 2 0 IKI3 family PTPRCAP PF15713.5 KIY66328.1 - 0.57 10.5 8.8 0.078 13.3 4.1 2.0 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated Glyco_hydro_43 PF04616.14 KIY66329.1 - 5e-41 140.9 1.4 6.2e-41 140.6 1.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 ATP-synt_Eps PF04627.13 KIY66330.1 - 3.2e-21 75.0 2.7 3.9e-21 74.8 2.7 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain PikAIV_N PF18605.1 KIY66330.1 - 0.28 10.8 4.4 0.4 10.3 4.4 1.3 1 0 0 1 1 1 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain FMO-like PF00743.19 KIY66331.1 - 5.8e-29 100.9 0.6 7.7e-28 97.2 0.6 2.4 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KIY66331.1 - 2e-23 83.1 0.0 3e-19 69.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KIY66331.1 - 1.3e-16 60.7 0.1 6.5e-11 42.0 0.0 2.6 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KIY66331.1 - 4.2e-12 45.9 0.0 4.8e-07 29.3 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 KIY66331.1 - 9.1e-07 29.4 0.0 0.061 13.9 0.0 3.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KIY66331.1 - 2e-06 27.3 0.0 3.8e-05 23.1 0.0 2.4 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KIY66331.1 - 1.3e-05 25.3 0.0 5e-05 23.4 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain 2-Hacid_dh_C PF02826.19 KIY66331.1 - 4.8e-05 22.8 0.1 0.14 11.5 0.0 2.4 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.24 KIY66331.1 - 5e-05 23.1 0.9 0.06 12.9 0.2 3.3 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KIY66331.1 - 7.5e-05 22.8 0.6 1 9.4 0.0 3.3 3 0 0 3 3 3 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KIY66331.1 - 8.6e-05 21.7 0.1 0.34 9.9 0.0 3.4 4 0 0 4 4 4 2 Lycopene cyclase protein HI0933_like PF03486.14 KIY66331.1 - 0.00024 19.9 0.6 0.0093 14.7 0.1 2.6 2 0 0 2 2 2 1 HI0933-like protein IlvN PF07991.12 KIY66331.1 - 0.00045 19.8 0.0 0.15 11.6 0.0 2.4 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Thi4 PF01946.17 KIY66331.1 - 0.00062 19.1 0.2 0.063 12.5 0.0 2.7 3 0 0 3 3 3 1 Thi4 family Shikimate_DH PF01488.20 KIY66331.1 - 0.00091 19.3 0.0 0.54 10.3 0.0 2.5 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 KIY66331.1 - 0.0028 18.1 0.0 0.2 12.1 0.1 2.9 2 1 0 2 2 2 1 Putative NAD(P)-binding 3HCDH_N PF02737.18 KIY66331.1 - 0.0046 16.9 0.0 2 8.3 0.0 2.4 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 KIY66331.1 - 0.0077 16.5 0.3 3.3 8.0 0.0 3.0 3 0 0 3 3 3 1 TrkA-N domain F420_oxidored PF03807.17 KIY66331.1 - 0.013 16.0 0.0 20 5.8 0.0 3.4 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent FAD_binding_2 PF00890.24 KIY66331.1 - 0.019 14.1 1.2 0.051 12.7 1.0 1.8 2 0 0 2 2 2 0 FAD binding domain ApbA PF02558.16 KIY66331.1 - 0.024 14.3 0.0 1.6 8.3 0.0 2.3 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.14 KIY66331.1 - 0.11 12.1 0.0 0.28 10.7 0.0 1.6 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF498 PF04430.14 KIY66331.1 - 0.13 12.4 0.0 0.94 9.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF498/DUF598) GIDA PF01134.22 KIY66331.1 - 0.23 10.5 5.5 3.4 6.7 0.4 2.5 3 0 0 3 3 3 0 Glucose inhibited division protein A Ribosomal_L38e PF01781.18 KIY66332.1 - 8.1e-34 115.5 1.6 9.3e-34 115.4 1.6 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family NPA PF16469.5 KIY66332.1 - 0.0057 17.2 0.1 0.0064 17.1 0.1 1.1 1 0 0 1 1 1 1 Nematode polyprotein allergen ABA-1 E1-E2_ATPase PF00122.20 KIY66333.1 - 2.6e-22 79.2 0.1 5e-22 78.3 0.1 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KIY66333.1 - 1.5e-14 54.8 0.0 2.8e-07 31.0 0.0 2.6 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KIY66333.1 - 1.6e-06 28.1 0.0 3.7e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KIY66333.1 - 0.011 15.5 0.0 0.038 13.7 0.0 1.9 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Glucos_trans_II PF14264.6 KIY66333.1 - 0.28 10.5 8.0 0.063 12.6 0.6 2.6 3 0 0 3 3 3 0 Glucosyl transferase GtrII G-alpha PF00503.20 KIY66334.1 - 1.3e-94 317.3 0.0 1.5e-94 317.1 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KIY66334.1 - 3e-10 39.8 0.1 8.5e-07 28.6 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family GTP_EFTU PF00009.27 KIY66334.1 - 0.082 12.4 0.0 0.99 8.9 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KIY66334.1 - 0.093 12.1 0.0 14 5.0 0.1 2.3 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region Vps55 PF04133.14 KIY66334.1 - 0.12 12.3 0.0 0.49 10.4 0.0 1.8 2 0 0 2 2 2 0 Vacuolar protein sorting 55 Sec63 PF02889.16 KIY66335.1 - 1.6e-25 89.7 0.2 2.8e-25 88.9 0.2 1.3 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.29 KIY66335.1 - 6.7e-16 58.6 0.2 1e-14 54.7 0.2 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIY66335.1 - 1.1e-09 38.7 0.0 4.4e-09 36.7 0.0 2.1 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIY66335.1 - 0.0019 18.2 0.0 0.047 13.7 0.0 2.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KIY66335.1 - 0.098 12.9 0.0 0.37 11.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain EF-hand_7 PF13499.6 KIY66336.1 - 4.7e-12 46.2 0.0 7.8e-07 29.5 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KIY66336.1 - 3.6e-11 42.0 0.2 0.00029 20.5 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 KIY66336.1 - 8.6e-10 37.5 0.0 0.00078 18.8 0.0 3.5 3 1 0 3 3 3 2 EF hand EF-hand_9 PF14658.6 KIY66336.1 - 9e-07 29.1 0.0 0.004 17.5 0.0 2.5 2 1 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 KIY66336.1 - 6.3e-05 22.7 0.1 0.00069 19.4 0.0 2.5 3 1 0 3 3 3 1 EF-hand domain pair EF-hand_11 PF08976.11 KIY66336.1 - 0.067 14.1 0.0 0.11 13.3 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain UPF0154 PF03672.13 KIY66336.1 - 0.13 12.3 0.0 6.6 6.9 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) ExbD PF02472.16 KIY66336.1 - 0.19 11.9 0.0 2.1 8.5 0.0 2.0 2 0 0 2 2 2 0 Biopolymer transport protein ExbD/TolR DDE_Tnp_IS66_C PF13817.6 KIY66336.1 - 0.22 11.8 0.2 0.6 10.4 0.1 1.7 2 0 0 2 2 2 0 IS66 C-terminal element SapB_1 PF05184.15 KIY66336.1 - 0.22 11.6 0.0 6.4 6.9 0.0 2.1 2 0 0 2 2 2 0 Saposin-like type B, region 1 SseC PF04888.12 KIY66338.1 - 0.011 15.4 9.0 0.014 15.0 9.0 1.2 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family CHDCT2 PF08074.11 KIY66338.1 - 0.012 15.8 0.4 0.027 14.6 0.2 1.7 2 1 0 2 2 2 0 CHDCT2 (NUC038) domain Baculo_PEP_C PF04513.12 KIY66338.1 - 0.017 15.2 7.4 0.15 12.1 0.9 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Tape_meas_lam_C PF09718.10 KIY66338.1 - 0.079 13.1 7.0 0.1 12.7 5.5 1.9 2 0 0 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) DUF5427 PF10310.9 KIY66338.1 - 0.15 11.0 0.2 0.21 10.5 0.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) FAM199X PF15814.5 KIY66338.1 - 0.24 10.4 6.4 0.29 10.1 6.4 1.2 1 0 0 1 1 1 0 Protein family FAM199X Helo_like_N PF17111.5 KIY66338.1 - 3.7 6.8 4.3 0.87 8.9 1.0 1.6 2 0 0 2 2 2 0 Fungal N-terminal domain of STAND proteins NolX PF05819.11 KIY66338.1 - 4.1 6.6 10.4 3.7 6.8 8.3 1.9 1 1 1 2 2 2 0 NolX protein FSA_C PF10479.9 KIY66338.1 - 9.3 4.2 7.3 11 4.0 7.3 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus DUF543 PF04418.12 KIY66339.1 - 5.9e-28 96.7 0.4 6.4e-28 96.5 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF543) BRO1 PF03097.18 KIY66340.1 - 5.1e-115 384.4 0.1 1.3e-114 383.1 0.1 1.6 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 KIY66340.1 - 1.5e-49 168.9 0.4 2.4e-49 168.2 0.4 1.4 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV ORC6 PF05460.13 KIY66340.1 - 0.097 11.9 0.0 0.097 11.9 0.0 2.4 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) Synaphin PF05835.12 KIY66340.1 - 0.22 11.8 2.7 0.51 10.6 2.7 1.5 1 0 0 1 1 1 0 Synaphin protein Adap_comp_sub PF00928.21 KIY66343.1 - 2.2e-91 305.9 0.0 5.5e-91 304.6 0.0 1.6 2 0 0 2 2 2 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KIY66343.1 - 3.4e-07 30.3 1.1 6.3e-07 29.4 1.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Thaumatin PF00314.17 KIY66344.1 - 4.4e-68 229.1 8.4 5.1e-68 228.9 8.4 1.0 1 0 0 1 1 1 1 Thaumatin family DAO PF01266.24 KIY66345.1 - 1e-34 120.7 0.3 1.3e-34 120.4 0.3 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KIY66345.1 - 5.1e-07 29.2 0.1 8.8e-07 28.4 0.1 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 KIY66345.1 - 1.4e-06 28.4 0.3 3.9e-06 27.0 0.3 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KIY66345.1 - 0.0016 17.6 0.2 0.0024 17.0 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 KIY66345.1 - 0.0017 17.8 0.0 0.39 10.0 0.0 2.8 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 KIY66345.1 - 0.0035 16.6 0.0 1.3 8.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KIY66345.1 - 0.0055 16.0 0.1 0.0088 15.3 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KIY66345.1 - 0.026 13.2 0.1 0.042 12.6 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_9 PF13454.6 KIY66345.1 - 0.077 13.0 0.1 0.72 9.8 0.0 2.5 2 1 0 2 2 2 0 FAD-NAD(P)-binding AA_permease_2 PF13520.6 KIY66346.1 - 1.1e-40 139.8 44.5 1.4e-40 139.5 44.5 1.1 1 0 0 1 1 1 1 Amino acid permease DUF3915 PF13054.6 KIY66347.1 - 0.0038 17.2 0.2 0.0067 16.4 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3915) PEX11 PF05648.14 KIY66347.1 - 0.19 11.2 0.1 0.37 10.2 0.1 1.4 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) DUF4770 PF15994.5 KIY66347.1 - 0.22 11.7 4.0 0.44 10.8 4.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Sugar_tr PF00083.24 KIY66349.1 - 3.9e-109 365.5 20.7 4.9e-109 365.2 20.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY66349.1 - 2.3e-19 69.5 21.9 2.3e-19 69.5 21.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2574 PF10836.8 KIY66351.1 - 0.11 12.4 2.4 0.62 10.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2574) DUF2975 PF11188.8 KIY66351.1 - 0.39 10.6 3.2 0.69 9.8 3.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) Trehalase PF01204.18 KIY66353.1 - 4.3e-167 557.0 0.0 5.3e-167 556.7 0.0 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 KIY66353.1 - 3e-14 52.4 0.1 5e-14 51.7 0.1 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain Sugar_tr PF00083.24 KIY66354.1 - 6.2e-126 420.9 17.6 1.1e-125 420.1 17.6 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY66354.1 - 1.7e-16 60.1 32.0 9.1e-12 44.6 6.5 2.4 1 1 0 2 2 2 2 Major Facilitator Superfamily SelK_SelG PF10961.8 KIY66354.1 - 0.48 11.1 1.9 60 4.3 0.1 3.8 3 0 0 3 3 3 0 Selenoprotein SelK_SelG DUF2530 PF10745.9 KIY66354.1 - 1.4 9.2 7.1 0.2 11.9 0.4 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) Nop10p PF04135.12 KIY66357.1 - 2.6e-22 78.6 0.4 3.1e-22 78.4 0.4 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family Phytoreo_S7 PF07236.11 KIY66357.1 - 0.085 11.2 0.0 0.089 11.1 0.0 1.0 1 0 0 1 1 1 0 Phytoreovirus S7 protein Fungal_trans PF04082.18 KIY66359.1 - 9.5e-34 116.6 0.0 1.6e-33 115.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY66359.1 - 1.1e-06 28.6 12.7 1.7e-06 28.0 12.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sds3 PF08598.11 KIY66360.1 - 1.1e-20 74.5 6.3 1.1e-20 74.5 6.3 2.4 2 1 0 2 2 2 1 Sds3-like Ferritin_2 PF13668.6 KIY66361.1 - 1.1e-43 148.7 3.1 1.6e-43 148.2 3.1 1.2 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.17 KIY66361.1 - 0.16 12.3 0.1 0.71 10.3 0.1 1.9 1 1 1 2 2 2 0 Rubrerythrin PQ-loop PF04193.14 KIY66362.1 - 7.6e-18 64.1 9.8 2.9e-11 43.0 0.9 3.8 4 1 1 5 5 5 2 PQ loop repeat GET2 PF08690.10 KIY66362.1 - 0.5 10.0 0.9 0.72 9.5 0.9 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 Ca_chan_IQ PF08763.11 KIY66363.1 - 0.19 12.0 0.0 0.35 11.1 0.0 1.3 1 0 0 1 1 1 0 Voltage gated calcium channel IQ domain Fer2 PF00111.27 KIY66364.1 - 1.5e-09 37.6 0.2 2.2e-09 37.1 0.2 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Sugar_tr PF00083.24 KIY66365.1 - 3.7e-125 418.3 20.4 4.8e-125 418.0 20.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY66365.1 - 7.7e-15 54.7 38.6 7.2e-10 38.3 9.1 2.4 1 1 0 2 2 2 2 Major Facilitator Superfamily DUF2530 PF10745.9 KIY66365.1 - 1.5 9.1 7.3 0.15 12.3 0.9 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) SelK_SelG PF10961.8 KIY66365.1 - 1.6 9.4 7.3 23 5.7 0.3 4.3 4 0 0 4 4 4 0 Selenoprotein SelK_SelG BTB PF00651.31 KIY66366.1 - 0.0023 18.2 0.0 0.0041 17.3 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain DUF4355 PF14265.6 KIY66366.1 - 2.7 8.3 9.8 4.6 7.5 9.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) TGT PF01702.18 KIY66367.1 - 2.5e-29 102.5 0.0 9.5e-20 71.0 0.0 2.5 2 1 0 2 2 2 2 Queuine tRNA-ribosyltransferase zf-C3HC4_3 PF13920.6 KIY66367.1 - 0.052 13.4 0.1 0.087 12.7 0.1 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PriCT_2 PF08707.11 KIY66368.1 - 0.032 14.6 0.1 0.074 13.4 0.1 1.6 1 0 0 1 1 1 0 Primase C terminal 2 (PriCT-2) SKG6 PF08693.10 KIY66368.1 - 0.061 12.7 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain TrbC PF04956.13 KIY66368.1 - 0.074 13.3 0.2 0.17 12.1 0.1 1.7 2 0 0 2 2 2 0 TrbC/VIRB2 family RAP1 PF07218.11 KIY66368.1 - 0.93 7.7 8.1 1.3 7.2 8.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Sporozoite_P67 PF05642.11 KIY66368.1 - 8.3 4.3 10.3 15 3.5 10.3 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TMEM154 PF15102.6 KIY66369.1 - 0.00043 20.2 0.1 0.0007 19.5 0.1 1.3 1 0 0 1 1 1 1 TMEM154 protein family EphA2_TM PF14575.6 KIY66369.1 - 0.0083 17.0 0.1 0.031 15.2 0.0 1.9 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain BatD PF13584.6 KIY66369.1 - 0.03 13.2 0.0 0.041 12.7 0.0 1.1 1 0 0 1 1 1 0 Oxygen tolerance DUF5527 PF17665.1 KIY66369.1 - 0.033 13.7 0.0 0.057 12.9 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5527) Hydrophob_seed PF14547.6 KIY66369.1 - 0.042 14.1 0.3 0.11 12.7 0.3 1.7 1 0 0 1 1 1 0 Hydrophobic seed protein Rod_cone_degen PF15201.6 KIY66369.1 - 0.099 12.8 0.3 0.93 9.6 0.0 2.7 3 0 0 3 3 3 0 Progressive rod-cone degeneration Sporozoite_P67 PF05642.11 KIY66369.1 - 0.3 9.1 5.3 0.35 8.9 5.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SPX PF03105.19 KIY66370.1 - 0.037 14.0 2.1 0.045 13.7 2.1 1.0 1 0 0 1 1 1 0 SPX domain DUF4470 PF14737.6 KIY66372.1 - 1.1e-21 76.8 0.0 4.4e-21 74.9 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4470) zf-MYND PF01753.18 KIY66372.1 - 9.8e-09 35.2 11.6 1.8e-08 34.3 11.6 1.5 1 0 0 1 1 1 1 MYND finger Meleagrin PF08189.11 KIY66372.1 - 1.3 8.8 5.0 2.6 7.8 4.6 1.8 1 1 0 1 1 1 0 Meleagrin/Cygnin family zf-C6H2 PF15801.5 KIY66372.1 - 1.6 9.1 7.8 4 7.8 7.8 1.7 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-HIT PF04438.16 KIY66372.1 - 2.8 7.9 7.1 5 7.1 7.1 1.4 1 0 0 1 1 1 0 HIT zinc finger Prefoldin PF02996.17 KIY66373.1 - 3.5e-26 91.5 0.1 1.6e-25 89.4 0.1 1.8 1 1 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 KIY66373.1 - 0.042 13.8 0.3 0.43 10.6 0.1 2.1 2 0 0 2 2 2 0 Prefoldin subunit zf-MYST PF17772.1 KIY66374.1 - 0.049 13.2 2.4 0.065 12.8 1.0 1.9 2 0 0 2 2 2 0 MYST family zinc finger domain TFIIS_C PF01096.18 KIY66374.1 - 0.094 12.6 0.7 1.3 9.0 0.1 2.3 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) XPA_N PF01286.18 KIY66374.1 - 0.17 12.0 1.1 6.5 6.9 0.1 2.5 2 0 0 2 2 2 0 XPA protein N-terminal zf-C2H2_4 PF13894.6 KIY66374.1 - 0.37 11.8 6.9 0.45 11.5 0.7 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KIY66374.1 - 3.5 8.2 10.9 0.78 10.3 2.5 3.5 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2 PF00096.26 KIY66374.1 - 7.5 7.2 9.7 0.33 11.5 0.8 2.8 3 0 0 3 3 3 0 Zinc finger, C2H2 type HMG_box PF00505.19 KIY66375.1 - 8.2e-11 42.2 1.0 1.1e-10 41.7 1.0 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KIY66375.1 - 0.0021 18.6 0.5 0.0027 18.3 0.5 1.2 1 0 0 1 1 1 1 HMG-box domain OTT_1508_deam PF14441.6 KIY66376.1 - 0.033 14.2 0.0 0.078 13.0 0.0 1.8 1 0 0 1 1 1 0 OTT_1508-like deaminase Nucleolin_bd PF16725.5 KIY66376.1 - 0.2 11.3 0.0 0.42 10.3 0.0 1.4 1 0 0 1 1 1 0 Nucleolin binding domain Nic96 PF04097.14 KIY66378.1 - 1.7e-140 469.5 0.0 2.2e-140 469.1 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 TPR_14 PF13428.6 KIY66378.1 - 0.56 11.2 4.7 59 4.9 0.1 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat p450 PF00067.22 KIY66379.1 - 3.5e-71 240.3 0.0 5e-71 239.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KIY66380.1 - 6.7e-65 219.6 0.0 1e-64 219.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_61 PF03443.14 KIY66381.1 - 8.1e-68 228.4 0.0 9.7e-68 228.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 F-box-like PF12937.7 KIY66382.1 - 2.1e-06 27.5 0.5 6.2e-05 22.8 0.0 2.6 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIY66382.1 - 0.01 15.7 3.3 2 8.4 1.1 3.0 2 0 0 2 2 2 0 F-box domain DUF4270 PF14092.6 KIY66384.1 - 0.086 11.9 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4270) F-box-like PF12937.7 KIY66385.1 - 1e-05 25.3 0.0 2.2e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KIY66386.1 - 8.2e-06 25.6 1.8 1.7e-05 24.6 0.2 2.2 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 KIY66388.1 - 3.8e-06 26.7 5.7 2.6e-05 24.0 5.7 2.4 1 1 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KIY66388.1 - 0.15 12.5 0.2 2.6 8.6 0.1 2.9 2 1 2 4 4 4 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KIY66389.1 - 1.6e-06 27.9 0.1 3.8e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KIY66390.1 - 7.6e-07 28.9 1.0 2.7e-06 27.1 1.0 2.0 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KIY66390.1 - 0.088 12.7 0.4 0.53 10.2 0.4 2.3 1 1 0 1 1 1 0 F-box domain BTB PF00651.31 KIY66391.1 - 2.6e-07 30.8 0.1 1.2e-06 28.7 0.0 2.1 2 1 1 3 3 3 1 BTB/POZ domain Ras PF00071.22 KIY66392.1 - 6.9e-52 175.3 0.0 7.8e-52 175.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIY66392.1 - 2.8e-23 82.4 0.0 3.7e-23 82.0 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIY66392.1 - 1.9e-07 30.7 0.0 4e-07 29.6 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family AAA_16 PF13191.6 KIY66392.1 - 0.016 15.6 0.0 0.046 14.1 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 KIY66392.1 - 0.023 14.6 0.0 1.1 9.1 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase Gtr1_RagA PF04670.12 KIY66392.1 - 0.024 14.0 0.0 0.026 13.9 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KIY66392.1 - 0.098 12.1 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 KIY66392.1 - 0.14 11.9 0.0 9.3 6.0 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Gpi1 PF05024.15 KIY66393.1 - 3.6e-62 209.8 7.3 6.3e-62 209.0 7.3 1.4 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) OPT PF03169.15 KIY66394.1 - 1.4e-129 433.5 42.0 1.7e-129 433.3 42.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF420 PF04238.12 KIY66394.1 - 7 6.9 8.4 0.25 11.6 0.4 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF420) OPT PF03169.15 KIY66395.1 - 3.8e-133 445.3 44.7 4.4e-133 445.1 44.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein TB2_DP1_HVA22 PF03134.19 KIY66395.1 - 3.9 7.5 10.4 0.34 10.9 0.3 3.4 2 1 1 3 3 3 0 TB2/DP1, HVA22 family F-box-like PF12937.7 KIY66396.1 - 0.0024 17.7 0.6 0.0064 16.4 0.6 1.8 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KIY66396.1 - 0.33 11.4 2.3 5.3 7.6 0.5 3.1 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KIY66399.1 - 0.00033 20.5 0.1 0.00084 19.2 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY66399.1 - 0.028 14.3 0.2 0.19 11.6 0.2 2.3 1 1 0 1 1 1 0 F-box domain F-box-like_2 PF13013.6 KIY66399.1 - 0.099 12.6 0.0 0.3 11.1 0.0 1.8 1 1 0 1 1 1 0 F-box-like domain F-box-like PF12937.7 KIY66400.1 - 2.1e-05 24.3 0.1 5.3e-05 23.0 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY66400.1 - 0.035 14.0 1.7 0.18 11.8 0.2 2.8 2 1 0 2 2 2 0 F-box domain F-box-like_2 PF13013.6 KIY66400.1 - 0.11 12.5 0.0 0.44 10.5 0.0 2.0 2 1 0 2 2 2 0 F-box-like domain SH3_1 PF00018.28 KIY66401.1 - 1.8e-05 24.2 1.7 2.8e-05 23.6 0.0 2.2 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KIY66401.1 - 0.00021 21.1 0.0 0.00021 21.1 0.0 2.6 3 1 0 3 3 3 1 Variant SH3 domain SH3_2 PF07653.17 KIY66401.1 - 0.0093 15.6 0.0 0.026 14.2 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Coa1 PF08695.10 KIY66402.1 - 2.9e-32 110.9 0.1 3.8e-32 110.5 0.1 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 DUF4307 PF14155.6 KIY66402.1 - 0.21 11.4 0.4 3.7 7.4 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4307) LysM PF01476.20 KIY66403.1 - 8.2e-15 54.6 0.2 4.1e-06 26.8 0.1 2.3 2 0 0 2 2 2 2 LysM domain DUF4772 PF15997.5 KIY66403.1 - 0.044 14.4 0.4 1 10.0 0.0 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4772) DUF3246 PF11596.8 KIY66403.1 - 3.7 6.9 15.2 0.1 12.0 5.5 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3246) PhzC-PhzF PF02567.16 KIY66405.1 - 8.1e-36 123.9 0.0 1.1e-35 123.5 0.0 1.1 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Aminotran_1_2 PF00155.21 KIY66406.1 - 3.8e-29 102.0 0.0 4.7e-29 101.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 KIY66406.1 - 1.6e-13 50.3 0.0 2.7e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase dbPDZ_assoc PF16610.5 KIY66406.1 - 0.12 12.7 0.1 0.33 11.2 0.1 1.7 1 0 0 1 1 1 0 Unstructured region between two PDZ domains on Dlg5 Tox-ODYAM1 PF15642.6 KIY66406.1 - 0.21 10.5 0.0 0.51 9.3 0.0 1.6 2 0 0 2 2 2 0 Toxin in Odyssella and Amoebophilus OPT PF03169.15 KIY66407.1 - 3.1e-162 541.4 53.3 3.9e-162 541.1 53.3 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein BofA PF07441.11 KIY66407.1 - 0.022 15.0 5.4 0.12 12.6 5.4 2.3 1 0 0 1 1 1 0 SigmaK-factor processing regulatory protein BofA Na_H_Exchanger PF00999.21 KIY66408.1 - 1.6e-61 208.2 25.5 2e-61 207.9 25.5 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF21 PF01595.20 KIY66408.1 - 0.76 9.5 5.9 0.51 10.0 1.6 2.4 2 0 0 2 2 2 0 Cyclin M transmembrane N-terminal domain AA_permease PF00324.21 KIY66409.1 - 3.2e-117 392.1 30.1 3.9e-117 391.8 30.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KIY66409.1 - 1.3e-36 126.3 32.9 1.9e-36 125.8 32.9 1.2 1 0 0 1 1 1 1 Amino acid permease Innexin PF00876.18 KIY66409.1 - 0.017 14.5 1.2 0.045 13.0 1.2 1.6 1 0 0 1 1 1 0 Innexin RdRP PF05183.12 KIY66410.1 - 1.7e-161 538.9 0.0 2.3e-161 538.4 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase GMC_oxred_N PF00732.19 KIY66412.1 - 2.8e-55 187.8 0.2 3.9e-55 187.3 0.2 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIY66412.1 - 1e-24 87.7 0.0 1.9e-24 86.9 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KIY66412.1 - 8.6e-05 22.7 0.1 0.0013 19.0 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KIY66412.1 - 0.00021 20.5 1.4 0.04 13.0 0.3 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KIY66412.1 - 0.00065 19.0 0.0 0.053 12.8 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIY66412.1 - 0.0034 17.0 1.9 0.0034 17.0 1.9 2.1 2 1 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KIY66412.1 - 0.0065 15.6 0.0 0.01 14.9 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 KIY66412.1 - 0.12 12.4 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Arm PF00514.23 KIY66413.1 - 1.6e-07 31.1 10.0 1 9.5 0.1 6.4 6 0 0 6 6 6 5 Armadillo/beta-catenin-like repeat Pkinase_Tyr PF07714.17 KIY66414.1 - 1.3e-11 44.3 0.0 1.6e-06 27.6 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KIY66414.1 - 2.5e-08 33.6 0.0 7e-08 32.2 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 KIY66414.1 - 0.02 14.8 0.0 0.022 14.7 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF2306 PF10067.9 KIY66415.1 - 0.0067 16.6 0.5 0.013 15.7 0.5 1.5 1 0 0 1 1 1 1 Predicted membrane protein (DUF2306) DUF420 PF04238.12 KIY66415.1 - 0.06 13.6 0.2 0.079 13.2 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF420) DUF2306 PF10067.9 KIY66416.1 - 3.9e-08 33.6 0.9 6.9e-08 32.8 0.9 1.4 1 0 0 1 1 1 1 Predicted membrane protein (DUF2306) AA_permease PF00324.21 KIY66417.1 - 9.1e-140 466.4 34.9 1.1e-139 466.2 34.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KIY66417.1 - 4.4e-37 127.9 38.0 5.8e-37 127.5 38.0 1.1 1 0 0 1 1 1 1 Amino acid permease 7tm_7 PF08395.12 KIY66417.1 - 2.8 7.0 9.4 0.79 8.9 0.1 2.7 3 0 0 3 3 3 0 7tm Chemosensory receptor MS_channel PF00924.18 KIY66418.1 - 1.9e-12 47.2 2.6 1.9e-12 47.2 2.6 1.6 2 0 0 2 2 2 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 KIY66418.1 - 1.4e-05 24.2 0.2 3e-05 23.2 0.2 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KIY66418.1 - 0.00022 20.9 0.1 0.0006 19.5 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 KIY66418.1 - 0.00053 19.4 0.3 0.0017 17.7 0.3 1.9 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 KIY66418.1 - 0.001 19.5 0.0 0.0029 18.0 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain pair Ac110_PIF PF07280.11 KIY66418.1 - 0.0064 16.3 3.3 0.016 15.0 3.3 1.7 1 0 0 1 1 1 1 Per os infectivity factor AC110 DUF2207 PF09972.9 KIY66418.1 - 0.073 11.8 1.2 0.83 8.3 0.1 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) MMPL PF03176.15 KIY66418.1 - 0.096 11.6 2.9 0.19 10.6 2.9 1.5 1 0 0 1 1 1 0 MMPL family DUF1129 PF06570.11 KIY66418.1 - 6.9 6.1 7.8 1.7 8.1 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Sugar_tr PF00083.24 KIY66419.1 - 1.8e-50 172.2 11.9 3.4e-50 171.2 11.9 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY66419.1 - 4.5e-23 81.7 17.6 4.5e-23 81.7 17.6 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1218 PF06749.12 KIY66420.1 - 0.0079 16.7 4.8 1.6 9.3 2.2 3.3 2 1 0 2 2 2 2 Protein of unknown function (DUF1218) MARVEL PF01284.23 KIY66420.1 - 0.45 10.5 8.1 0.18 11.9 2.5 2.3 1 1 1 2 2 2 0 Membrane-associating domain DUF2306 PF10067.9 KIY66422.1 - 0.003 17.8 2.9 0.003 17.8 2.9 1.5 2 0 0 2 2 2 1 Predicted membrane protein (DUF2306) DUF3169 PF11368.8 KIY66422.1 - 0.84 9.1 6.7 0.44 10.0 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3169) SprB PF13573.6 KIY66423.1 - 0.021 14.6 0.2 0.087 12.6 0.2 2.1 1 0 0 1 1 1 0 SprB repeat DUF3039 PF11238.8 KIY66423.1 - 0.69 9.7 2.1 3 7.7 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3039) PorA PF11271.8 KIY66424.1 - 0.041 13.2 0.5 0.054 12.8 0.5 1.1 1 0 0 1 1 1 0 Porin PorA COPI_C PF06957.11 KIY66424.1 - 0.086 11.6 2.2 0.12 11.1 2.2 1.1 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Clathrin_H_link PF13838.6 KIY66426.1 - 0.096 12.6 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Clathrin-H-link Lipase_3 PF01764.25 KIY66428.1 - 1.4e-29 102.8 0.0 1.8e-29 102.5 0.0 1.1 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 KIY66428.1 - 0.0076 15.8 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 KIY66428.1 - 0.12 13.0 0.2 0.17 12.5 0.2 1.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family WD40 PF00400.32 KIY66429.1 - 1.2e-14 54.5 13.9 1.9e-05 25.3 4.2 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat eIF2A PF08662.11 KIY66429.1 - 7.2e-05 22.7 0.0 0.15 11.9 0.0 2.2 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 KIY66429.1 - 9.6e-05 22.6 0.2 0.14 12.5 0.0 4.2 2 1 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain DUF1961 PF09224.11 KIY66429.1 - 0.14 11.5 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1961) Stealth_CR2 PF11380.8 KIY66430.1 - 9.2e-16 58.0 1.4 9.5e-10 38.6 0.0 3.7 4 0 0 4 4 4 2 Stealth protein CR2, conserved region 2 Stealth_CR3 PF17102.5 KIY66430.1 - 5.4e-07 29.4 1.0 5.4e-07 29.4 1.0 2.2 2 0 0 2 2 2 1 Stealth protein CR3, conserved region 3 Stealth_CR1 PF17101.5 KIY66430.1 - 0.0069 16.1 1.6 0.015 15.0 1.6 1.6 1 0 0 1 1 1 1 Stealth protein CR1, conserved region 1 EF-hand_5 PF13202.6 KIY66430.1 - 0.16 11.6 0.1 0.62 9.7 0.0 2.1 2 0 0 2 2 2 0 EF hand GMC_oxred_N PF00732.19 KIY66431.1 - 5.5e-49 167.1 0.0 2.4e-48 165.0 0.0 2.0 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIY66431.1 - 1e-30 107.2 0.0 1.7e-30 106.4 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Retrotrans_gag PF03732.17 KIY66433.1 - 0.00032 20.9 0.2 0.00053 20.2 0.2 1.3 1 0 0 1 1 1 1 Retrotransposon gag protein Pkinase PF00069.25 KIY66434.1 - 2.6e-52 177.8 0.0 8.8e-52 176.1 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY66434.1 - 4.3e-30 104.9 0.0 1.3e-28 100.0 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 KIY66434.1 - 3.9e-09 36.7 0.0 9.6e-09 35.5 0.0 1.7 1 1 0 1 1 1 1 FHA domain Kinase-like PF14531.6 KIY66434.1 - 1.4e-05 24.5 0.0 2.2e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KIY66434.1 - 6.8e-05 22.3 0.0 0.00011 21.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIY66434.1 - 0.015 15.2 0.1 0.036 14.0 0.1 1.8 1 0 0 1 1 1 0 Phosphotransferase enzyme family Peptidase_M24 PF00557.24 KIY66435.1 - 7.7e-42 143.3 0.0 1.2e-41 142.7 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N_2 PF16189.5 KIY66435.1 - 1.2e-40 139.2 0.0 4.9e-39 134.0 0.0 2.4 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Peptidase_M24_C PF16188.5 KIY66435.1 - 2.9e-20 72.1 0.8 7e-20 70.9 0.8 1.7 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 KIY66435.1 - 6.9e-15 55.9 0.0 1.3e-14 55.0 0.0 1.5 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain DUF3302 PF11742.8 KIY66436.1 - 0.16 12.1 0.2 0.16 12.1 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3302) Sec6 PF06046.13 KIY66437.1 - 2.5e-145 485.1 0.4 2.5e-145 485.1 0.4 1.4 2 0 0 2 2 2 1 Exocyst complex component Sec6 Fes1 PF08609.10 KIY66437.1 - 0.0056 17.5 1.4 0.045 14.6 0.1 3.2 3 0 0 3 3 3 1 Nucleotide exchange factor Fes1 HECT PF00632.25 KIY66437.1 - 0.092 12.2 0.1 0.17 11.3 0.1 1.3 1 0 0 1 1 1 0 HECT-domain (ubiquitin-transferase) DASH_Duo1 PF08651.10 KIY66437.1 - 1.1 9.1 3.7 7.3 6.5 0.3 3.9 2 1 1 3 3 3 0 DASH complex subunit Duo1 NPV_P10 PF05531.12 KIY66437.1 - 1.1 9.7 4.5 3 8.4 2.3 3.0 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein FAD_binding_3 PF01494.19 KIY66438.1 - 2.7e-24 86.1 0.0 8.8e-12 44.9 0.0 2.3 2 1 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 KIY66438.1 - 1.9e-11 43.7 0.1 0.00051 19.2 0.0 3.1 3 0 0 3 3 3 3 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KIY66438.1 - 1.4e-06 27.8 0.0 0.00019 20.8 0.0 2.3 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 KIY66438.1 - 2e-05 23.8 0.0 3.2e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase Trp_halogenase PF04820.14 KIY66438.1 - 2.3e-05 23.5 0.0 0.045 12.6 0.0 2.9 3 0 0 3 3 3 2 Tryptophan halogenase NAD_binding_9 PF13454.6 KIY66438.1 - 2.9e-05 24.1 0.0 0.003 17.6 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 KIY66438.1 - 0.0018 17.6 0.0 0.0033 16.7 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 KIY66438.1 - 0.0034 16.7 0.0 0.71 9.1 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KIY66438.1 - 0.011 14.5 0.0 0.18 10.4 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_2 PF00890.24 KIY66438.1 - 0.034 13.2 0.3 0.073 12.1 0.3 1.5 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.24 KIY66438.1 - 0.044 13.4 0.1 0.2 11.2 0.1 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KIY66438.1 - 0.055 13.7 0.1 0.15 12.3 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KIY66438.1 - 0.17 11.2 0.6 0.56 9.5 0.5 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase Malate_synthase PF01274.22 KIY66439.1 - 3.9e-201 668.9 0.0 4.7e-201 668.6 0.0 1.0 1 0 0 1 1 1 1 Malate synthase CHD5 PF04420.14 KIY66440.1 - 6.8e-57 191.8 4.0 9e-57 191.4 4.0 1.1 1 0 0 1 1 1 1 CHD5-like protein Lipoprotein_6 PF01441.19 KIY66440.1 - 0.0033 17.5 0.1 0.0046 17.0 0.1 1.2 1 0 0 1 1 1 1 Lipoprotein BHD_2 PF10404.9 KIY66440.1 - 0.023 15.6 0.4 0.59 11.1 0.2 2.3 2 0 0 2 2 2 0 Rad4 beta-hairpin domain 2 ABC_membrane_3 PF13748.6 KIY66440.1 - 0.13 11.5 0.3 0.15 11.2 0.3 1.1 1 0 0 1 1 1 0 ABC transporter transmembrane region DUF565 PF04483.12 KIY66440.1 - 0.73 10.4 3.2 28 5.3 3.2 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF565) Glycos_transf_1 PF00534.20 KIY66441.1 - 1.6e-29 102.6 0.0 4.9e-29 101.1 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KIY66441.1 - 8e-25 87.8 0.0 1.4e-24 87.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 KIY66441.1 - 6.7e-23 81.6 0.0 1.7e-22 80.3 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KIY66441.1 - 9.6e-12 45.6 1.0 2.2e-10 41.2 0.0 2.8 1 1 2 3 3 3 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 KIY66441.1 - 0.0025 18.1 0.1 0.065 13.6 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferases group 1 HMG_CoA_synt_C PF08540.10 KIY66443.1 - 2.9e-87 292.9 0.1 3.5e-87 292.6 0.1 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 KIY66443.1 - 1.4e-83 279.0 0.1 2e-83 278.5 0.1 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal ACP_syn_III PF08545.10 KIY66443.1 - 0.026 14.4 1.3 0.066 13.1 0.1 2.3 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF3641 PF12345.8 KIY66443.1 - 0.031 14.3 0.0 2.8 8.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3641) FAD_binding_3 PF01494.19 KIY66444.1 - 4.5e-64 216.9 0.0 5.8e-64 216.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 KIY66444.1 - 2.9e-05 23.3 0.9 4.8e-05 22.6 0.9 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KIY66444.1 - 3.2e-05 23.3 0.1 6.6e-05 22.3 0.1 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 KIY66444.1 - 9.3e-05 22.6 0.6 0.00031 20.9 0.6 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KIY66444.1 - 0.00022 20.6 0.7 0.0021 17.3 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIY66444.1 - 0.00046 20.7 0.8 0.033 14.7 0.3 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KIY66444.1 - 0.0015 17.3 0.5 0.0025 16.6 0.5 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.7 KIY66444.1 - 0.0021 17.5 0.0 0.0027 17.1 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 KIY66444.1 - 0.0022 17.6 0.2 0.0086 15.7 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KIY66444.1 - 0.0085 15.0 0.2 0.013 14.4 0.2 1.2 1 0 0 1 1 1 1 Tryptophan halogenase Lycopene_cycl PF05834.12 KIY66444.1 - 0.0094 15.0 0.2 0.014 14.5 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KIY66444.1 - 0.011 15.1 0.0 0.017 14.4 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KIY66444.1 - 0.057 12.5 0.4 0.088 11.9 0.4 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Tma16 PF11176.8 KIY66445.1 - 7.8e-44 149.1 2.3 9.9e-44 148.8 2.3 1.1 1 0 0 1 1 1 1 Translation machinery-associated protein 16 Med10 PF09748.9 KIY66446.1 - 6.7e-20 71.3 0.0 8.2e-20 71.0 0.0 1.1 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex CAP PF00188.26 KIY66447.1 - 4.3e-25 89.0 2.8 5.4e-25 88.7 2.8 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family PGA2 PF07543.12 KIY66448.1 - 0.041 13.9 3.4 0.066 13.2 3.4 1.4 1 0 0 1 1 1 0 Protein trafficking PGA2 PBP1_TM PF14812.6 KIY66448.1 - 0.13 12.7 4.3 0.14 12.5 2.2 2.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PI-PLC-X PF00388.19 KIY66449.1 - 1.9e-55 186.4 0.0 6.9e-55 184.6 0.0 2.0 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KIY66449.1 - 2.1e-44 150.5 0.0 4.4e-44 149.5 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 KIY66449.1 - 9.7e-10 38.7 0.0 1.3e-08 35.1 0.0 2.7 2 1 0 2 2 2 1 C2 domain EF-hand_10 PF14788.6 KIY66449.1 - 0.00011 22.0 0.9 0.0003 20.6 0.9 1.8 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 KIY66449.1 - 0.052 14.0 8.4 0.15 12.5 4.8 2.7 1 1 2 3 3 3 0 EF-hand domain pair PH_14 PF17787.1 KIY66449.1 - 0.083 12.7 0.0 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 PH domain PH_12 PF16457.5 KIY66449.1 - 0.089 13.3 0.0 0.31 11.6 0.0 2.0 1 0 0 1 1 1 0 Pleckstrin homology domain EF-hand_6 PF13405.6 KIY66449.1 - 2.1 8.5 5.8 12 6.2 2.3 3.2 3 0 0 3 3 3 0 EF-hand domain EF-hand_1 PF00036.32 KIY66449.1 - 6.2 6.6 5.8 14 5.5 0.9 3.4 3 1 1 4 4 4 0 EF hand TFIIB PF00382.19 KIY66450.1 - 1.4e-36 124.3 0.9 4.7e-17 61.8 0.2 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 KIY66450.1 - 1.2e-25 89.7 4.2 1.2e-25 89.7 4.2 2.4 2 0 0 2 2 2 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.12 KIY66450.1 - 1.7e-07 30.7 1.5 3.6e-07 29.6 1.5 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 KIY66450.1 - 0.00015 21.5 1.2 0.014 15.1 0.3 2.3 2 0 0 2 2 2 1 Cyclin, N-terminal domain DZR PF12773.7 KIY66450.1 - 0.11 12.6 0.4 0.21 11.6 0.4 1.4 1 0 0 1 1 1 0 Double zinc ribbon Auto_anti-p27 PF06677.12 KIY66450.1 - 0.14 12.4 0.6 0.25 11.5 0.6 1.4 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-RRN7 PF11781.8 KIY66450.1 - 0.47 10.2 6.0 0.038 13.7 1.1 1.8 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 HTH_AsnC-type PF13404.6 KIY66450.1 - 0.86 9.5 0.0 0.86 9.5 0.0 2.8 3 0 0 3 3 3 0 AsnC-type helix-turn-helix domain Rtf2 PF04641.12 KIY66450.1 - 1.3 8.4 12.3 0.27 10.6 0.7 2.4 2 0 0 2 2 2 0 Rtf2 RING-finger Rrn6 PF10214.9 KIY66450.1 - 1.6 7.2 6.3 0.13 10.8 0.4 1.8 2 0 0 2 2 2 0 RNA polymerase I-specific transcription-initiation factor DAO PF01266.24 KIY66452.1 - 1.4e-24 87.4 0.1 1.7e-24 87.1 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 KIY66452.1 - 0.00015 22.1 0.0 0.00029 21.2 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Pyr_redox_2 PF07992.14 KIY66452.1 - 0.00055 19.3 0.0 0.0012 18.2 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIY66452.1 - 0.00068 19.8 0.3 0.0015 18.7 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KIY66452.1 - 0.0035 17.9 0.1 0.0075 16.8 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KIY66452.1 - 0.009 15.1 0.1 0.014 14.5 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 KIY66452.1 - 0.016 14.5 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 KIY66452.1 - 0.085 12.2 0.1 3.1 7.1 0.3 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.22 KIY66452.1 - 0.088 11.9 0.1 0.16 11.0 0.1 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_binding_3 PF01494.19 KIY66452.1 - 0.18 11.1 0.0 0.41 9.9 0.0 1.6 1 0 0 1 1 1 0 FAD binding domain DUF4611 PF15387.6 KIY66453.1 - 0.7 10.1 3.0 1.4 9.2 3.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) GCIP PF13324.6 KIY66453.1 - 5 6.6 4.7 7.7 6.0 4.7 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting DUF5022 PF16425.5 KIY66455.1 - 0.1 12.0 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5022) zf-SCNM1 PF15803.5 KIY66455.1 - 0.24 11.1 0.1 0.24 11.1 0.1 1.9 2 0 0 2 2 2 0 Zinc-finger of sodium channel modifier 1 Arm PF00514.23 KIY66456.1 - 0.0098 15.9 0.7 1.7 8.8 0.0 4.4 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat Phage_integrase PF00589.22 KIY66456.1 - 0.2 11.4 0.2 1.3 8.8 0.0 2.3 3 0 0 3 3 3 0 Phage integrase family MOZART1 PF12554.8 KIY66457.1 - 3.7e-26 90.7 0.9 4.5e-26 90.4 0.9 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated Zds_C PF08632.10 KIY66458.1 - 7.8e-29 99.2 0.2 1.3e-28 98.5 0.2 1.3 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term LEA_3 PF03242.13 KIY66458.1 - 0.35 11.6 0.1 0.35 11.6 0.1 3.1 3 0 0 3 3 3 0 Late embryogenesis abundant protein HyaE PF07449.11 KIY66459.1 - 0.045 13.7 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE DNA_pol_phi PF04931.13 KIY66459.1 - 2 6.4 5.7 3 5.8 5.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi FAM176 PF14851.6 KIY66459.1 - 2.8 7.6 7.1 2.5 7.7 5.4 1.7 2 0 0 2 2 2 0 FAM176 family CENP-B_dimeris PF09026.10 KIY66459.1 - 5.8 7.4 10.9 12 6.3 10.9 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Mito_carr PF00153.27 KIY66460.1 - 5.5e-64 212.1 3.9 1.1e-21 76.5 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein eIF3g PF12353.8 KIY66461.1 - 1e-43 148.7 2.8 1e-43 148.7 2.8 1.6 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 KIY66461.1 - 9.4e-17 60.6 0.1 1.7e-16 59.8 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KIY66461.1 - 0.039 13.9 0.0 0.066 13.2 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KIY66461.1 - 0.047 13.7 1.4 0.1 12.7 0.0 2.2 3 0 0 3 3 3 0 RNA binding motif RRM_occluded PF16842.5 KIY66461.1 - 0.049 13.5 0.0 0.37 10.7 0.0 2.2 2 0 0 2 2 2 0 Occluded RNA-recognition motif PHM7_cyt PF14703.6 KIY66461.1 - 0.28 11.4 4.0 13 6.0 0.2 3.0 2 1 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter Myc_N PF01056.18 KIY66462.1 - 0.043 13.7 2.0 0.061 13.2 2.0 1.1 1 0 0 1 1 1 0 Myc amino-terminal region CENP-B_dimeris PF09026.10 KIY66462.1 - 0.71 10.3 10.6 1.6 9.1 10.6 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain TFIIS_M PF07500.14 KIY66463.1 - 2.4e-31 108.5 0.7 6.3e-31 107.2 0.7 1.7 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 KIY66463.1 - 2.9e-19 68.6 9.8 5.4e-19 67.8 9.8 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 KIY66463.1 - 1e-09 38.3 1.1 2.8e-09 36.9 0.3 2.2 2 0 0 2 2 2 1 TFIIS helical bundle-like domain zinc_ribbon_4 PF13717.6 KIY66463.1 - 0.12 12.3 4.2 0.16 11.9 0.4 2.6 2 0 0 2 2 2 0 zinc-ribbon domain TF_Zn_Ribbon PF08271.12 KIY66463.1 - 0.19 11.3 1.7 0.42 10.2 1.7 1.7 1 1 0 1 1 1 0 TFIIB zinc-binding Striatin PF08232.12 KIY66463.1 - 2 9.0 6.9 13 6.3 1.7 2.2 2 0 0 2 2 2 0 Striatin family SlyX PF04102.12 KIY66464.1 - 0.015 15.9 0.1 0.38 11.4 0.0 2.6 2 0 0 2 2 2 0 SlyX Trp_halogenase PF04820.14 KIY66465.1 - 0.00024 20.1 0.0 0.28 10.0 0.0 3.0 3 0 0 3 3 3 2 Tryptophan halogenase FAD_oxidored PF12831.7 KIY66465.1 - 0.00058 19.3 0.0 0.0015 18.0 0.0 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIY66465.1 - 0.042 13.1 0.1 0.15 11.3 0.0 1.7 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KIY66467.1 - 7.2e-05 21.8 0.0 0.0018 17.2 0.0 2.3 2 0 0 2 2 2 1 Tryptophan halogenase DRMBL PF07522.14 KIY66467.1 - 0.021 15.0 0.0 0.042 14.0 0.0 1.4 1 0 0 1 1 1 0 DNA repair metallo-beta-lactamase DAO PF01266.24 KIY66467.1 - 0.059 12.9 0.0 0.085 12.4 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Glyco_transf_15 PF01793.16 KIY66469.1 - 8.8e-121 403.1 5.9 1.1e-120 402.8 5.9 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DUF5106 PF17127.4 KIY66469.1 - 0.1 12.9 0.5 0.22 11.8 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) NAP PF00956.18 KIY66470.1 - 0.11 11.6 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Nucleosome assembly protein (NAP) DUF4245 PF14030.6 KIY66471.1 - 0.025 14.6 10.6 0.031 14.3 10.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4245) Fungal_trans PF04082.18 KIY66473.1 - 7.2e-10 38.3 0.0 1.3e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2_4 PF13894.6 KIY66473.1 - 1.9e-07 31.3 9.5 0.0015 19.2 1.2 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KIY66473.1 - 2e-06 27.9 9.1 0.0063 16.9 1.1 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KIY66473.1 - 0.0025 18.2 2.3 0.0025 18.2 2.3 3.6 3 1 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KIY66473.1 - 0.008 16.4 6.4 0.16 12.3 0.1 2.8 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding Zn-C2H2_12 PF18112.1 KIY66473.1 - 0.036 14.5 0.6 0.091 13.2 0.6 1.6 1 0 0 1 1 1 0 Autophagy receptor zinc finger-C2H2 domain Zn_clus PF00172.18 KIY66473.1 - 0.06 13.5 7.9 0.18 12.0 7.9 1.8 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_2 PF12756.7 KIY66473.1 - 0.12 12.8 7.0 4.6 7.6 1.1 2.6 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.12 KIY66473.1 - 0.13 12.5 3.6 0.47 10.8 3.6 2.0 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 KIY66473.1 - 4.2 7.9 11.1 2.7 8.5 0.2 3.2 3 0 0 3 3 3 0 Zinc-finger of C2H2 type MFS_1 PF07690.16 KIY66474.1 - 3e-28 98.8 29.9 3e-28 98.8 29.9 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Zn_ribbon_17 PF17120.5 KIY66475.1 - 6.5e-10 38.5 11.6 6.5e-10 38.5 11.6 1.9 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type WD40 PF00400.32 KIY66475.1 - 0.0011 19.7 0.3 0.0011 19.7 0.3 5.1 3 1 0 3 3 3 1 WD domain, G-beta repeat RWD PF05773.22 KIY66475.1 - 0.02 15.2 0.0 0.041 14.2 0.0 1.4 1 0 0 1 1 1 0 RWD domain DZR PF12773.7 KIY66475.1 - 5.3 7.1 13.9 2.3 8.3 11.2 1.8 2 0 0 2 2 2 0 Double zinc ribbon DUF2385 PF09539.10 KIY66476.1 - 0.0084 16.6 0.2 0.018 15.6 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2385) HAD_2 PF13419.6 KIY66477.1 - 5.2e-17 62.5 0.0 1.1e-16 61.4 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KIY66477.1 - 2.9e-11 44.1 0.5 5.7e-09 36.6 0.5 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KIY66477.1 - 0.0005 20.5 0.0 0.00079 19.9 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 KIY66477.1 - 0.00072 19.6 0.0 0.76 9.9 0.0 2.5 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase zf-ZPR1 PF03367.13 KIY66478.1 - 4.6e-111 367.8 0.8 5.6e-58 195.3 0.0 2.1 2 0 0 2 2 2 2 ZPR1 zinc-finger domain HypA PF01155.19 KIY66478.1 - 0.007 16.4 2.6 1.9 8.5 0.1 2.6 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn-ribbon_8 PF09723.10 KIY66478.1 - 0.01 16.0 5.7 4.3 7.5 0.1 3.7 3 0 0 3 3 3 0 Zinc ribbon domain zinc-ribbons_6 PF07191.12 KIY66478.1 - 0.028 14.4 1.7 2.5 8.2 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbons DnaJ_CXXCXGXG PF00684.19 KIY66478.1 - 0.071 13.5 3.5 0.76 10.2 0.5 2.4 2 0 0 2 2 2 0 DnaJ central domain Lar_restr_allev PF14354.6 KIY66478.1 - 0.78 10.2 4.2 3.2 8.2 0.2 2.8 2 1 0 2 2 2 0 Restriction alleviation protein Lar DZR PF12773.7 KIY66478.1 - 1.6 8.8 7.4 3.4 7.7 0.2 3.1 2 1 1 3 3 3 0 Double zinc ribbon zinc_ribbon_2 PF13240.6 KIY66478.1 - 2.1 8.2 10.6 5.5 6.8 0.4 3.7 4 0 0 4 4 4 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 KIY66478.1 - 2.2 7.8 7.1 4.5 6.8 0.2 3.3 3 0 0 3 3 3 0 zinc-ribbon domain Fungal_trans PF04082.18 KIY66479.1 - 0.00032 19.8 0.4 0.00067 18.8 0.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY66479.1 - 0.00042 20.4 5.5 0.00042 20.4 5.5 2.6 2 1 1 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.26 KIY66479.1 - 0.00097 19.5 7.1 0.00097 19.5 7.1 3.4 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIY66479.1 - 0.0031 18.2 19.2 0.01 16.6 4.9 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KIY66479.1 - 0.01 16.3 20.0 0.024 15.1 9.9 3.1 3 0 0 3 3 3 0 Zinc-finger double domain zf-met PF12874.7 KIY66479.1 - 0.014 15.8 1.0 0.014 15.8 1.0 2.8 3 0 0 3 3 3 0 Zinc-finger of C2H2 type BolA PF01722.18 KIY66479.1 - 0.2 12.0 4.1 0.45 10.8 4.1 1.5 1 0 0 1 1 1 0 BolA-like protein zf-C2H2_jaz PF12171.8 KIY66479.1 - 0.49 10.7 11.7 0.06 13.6 1.9 2.9 2 1 1 3 3 3 0 Zinc-finger double-stranded RNA-binding PSI_integrin PF17205.3 KIY66479.1 - 0.77 9.6 5.6 0.091 12.5 0.6 2.1 2 0 0 2 2 2 0 Integrin plexin domain zf-H2C2_5 PF13909.6 KIY66479.1 - 9.8 6.0 16.0 3.7 7.4 2.6 2.7 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf_CCCH_4 PF18345.1 KIY66480.1 - 4.9e-20 70.9 36.1 6e-06 26.1 1.8 4.7 4 0 0 4 4 4 4 Zinc finger domain IBR PF01485.21 KIY66480.1 - 7.5e-15 54.9 19.6 4.1e-11 42.9 3.2 4.6 4 1 0 4 4 4 2 IBR domain, a half RING-finger domain Torus PF16131.5 KIY66480.1 - 6.7e-14 52.5 18.6 0.00014 22.5 0.5 4.6 1 1 3 4 4 4 4 Torus domain zf-CCCH PF00642.24 KIY66480.1 - 3.3e-13 49.2 29.3 0.0027 17.6 2.8 4.9 4 0 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 KIY66480.1 - 8.6e-12 44.7 0.0 1.8e-05 24.5 0.0 4.1 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_4 PF18044.1 KIY66480.1 - 1e-10 41.2 31.4 0.00014 21.5 2.3 4.7 4 0 0 4 4 4 4 CCCH-type zinc finger zf-CCCH_3 PF15663.5 KIY66480.1 - 3.6e-10 40.0 11.8 0.00012 22.3 1.4 3.8 3 0 0 3 3 3 2 Zinc-finger containing family zf-RING_UBOX PF13445.6 KIY66480.1 - 1.1e-05 25.4 6.3 1.1e-05 25.4 6.3 3.5 3 1 0 3 3 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KIY66480.1 - 0.00051 20.1 8.1 0.00051 20.1 8.1 4.0 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 KIY66480.1 - 0.0016 18.3 11.3 0.0016 18.3 11.3 4.3 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KIY66480.1 - 0.002 18.0 7.7 0.002 18.0 7.7 4.8 4 1 1 5 5 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIY66480.1 - 0.0058 16.6 9.8 0.0058 16.6 9.8 4.9 3 2 1 4 4 1 1 zinc-RING finger domain zf-CCCH_2 PF14608.6 KIY66480.1 - 0.13 12.8 41.6 0.039 14.4 5.2 5.6 5 0 0 5 5 5 0 RNA-binding, Nab2-type zinc finger zf-CCHH PF10283.9 KIY66480.1 - 2.5 8.2 7.4 5.3 7.1 0.6 3.1 2 0 0 2 2 2 0 PBZ domain Glyco_hydro_92 PF07971.12 KIY66481.1 - 1.8e-122 409.6 1.1 2.1e-122 409.4 1.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 KIY66481.1 - 2.7e-52 178.1 0.0 4.6e-52 177.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain TetR_C_31 PF17940.1 KIY66482.1 - 0.095 12.9 0.1 0.12 12.6 0.1 1.2 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain HlyIII PF03006.20 KIY66484.1 - 7.2e-39 133.8 18.6 1e-38 133.3 18.6 1.2 1 0 0 1 1 1 1 Haemolysin-III related Pept_tRNA_hydro PF01195.19 KIY66485.1 - 8.6e-28 97.4 0.0 1e-27 97.1 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase Arrestin_N PF00339.29 KIY66486.1 - 0.00054 20.0 0.1 0.0082 16.2 0.0 2.5 1 1 1 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Aspzincin_M35 PF14521.6 KIY66487.1 - 6.6e-41 140.2 8.2 6.6e-41 140.2 8.2 1.5 2 0 0 2 2 2 1 Lysine-specific metallo-endopeptidase HRXXH PF13933.6 KIY66487.1 - 0.096 12.2 4.5 0.63 9.6 0.3 2.1 1 1 1 2 2 2 0 Putative peptidase family F-box-like PF12937.7 KIY66488.1 - 0.00052 19.9 2.2 0.0023 17.8 2.2 2.2 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KIY66488.1 - 1.8 8.5 4.7 4.1 7.4 0.1 3.2 4 0 0 4 4 4 0 F-box domain LRR_8 PF13855.6 KIY66488.1 - 2.9 7.7 7.1 0.62 9.9 1.7 2.6 3 1 0 3 3 3 0 Leucine rich repeat Pkinase_Tyr PF07714.17 KIY66492.1 - 7.1e-35 120.5 0.0 1e-34 120.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIY66492.1 - 1.9e-30 106.1 0.0 3e-30 105.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KIY66492.1 - 0.0006 18.7 0.0 0.00097 18.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 KIY66493.1 - 4.7e-31 108.0 0.0 6.5e-31 107.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIY66493.1 - 9.3e-29 100.6 0.0 1.3e-28 100.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KIY66493.1 - 0.04 12.7 0.0 0.14 10.9 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase SEP PF08059.13 KIY66496.1 - 8.2e-22 77.6 0.0 1.7e-21 76.6 0.0 1.6 1 0 0 1 1 1 1 SEP domain UBX PF00789.20 KIY66496.1 - 4.9e-14 52.3 0.0 7.7e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 UBX domain Ammonium_transp PF00909.21 KIY66497.1 - 9e-115 383.5 28.6 1e-114 383.4 28.6 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family NOA36 PF06524.12 KIY66500.1 - 0.64 9.3 3.7 1.4 8.2 3.7 1.5 1 0 0 1 1 1 0 NOA36 protein PMP1_2 PF08114.11 KIY66501.1 - 0.051 13.3 1.2 0.12 12.1 1.2 1.5 1 0 0 1 1 1 0 ATPase proteolipid family DUF5510 PF17629.2 KIY66501.1 - 0.063 13.2 0.5 0.13 12.2 0.5 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5510) USP8_dimer PF08969.11 KIY66502.1 - 0.027 14.7 0.3 0.05 13.8 0.3 1.4 1 0 0 1 1 1 0 USP8 dimerisation domain L27_1 PF09058.10 KIY66502.1 - 0.2 11.7 1.5 0.8 9.7 0.2 2.2 2 0 0 2 2 2 0 L27_1 Metal_resist PF13801.6 KIY66502.1 - 4.5 7.5 10.0 2 8.6 5.4 2.4 2 0 0 2 2 2 0 Heavy-metal resistance Pkinase PF00069.25 KIY66503.1 - 1.8e-10 40.7 0.0 2e-10 40.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY66503.1 - 2.1e-10 40.3 0.0 2.4e-10 40.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase zf-Mss51 PF13824.6 KIY66504.1 - 0.059 13.5 1.0 0.11 12.6 1.0 1.4 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Pkinase PF00069.25 KIY66505.1 - 1.2e-13 51.0 0.0 1.6e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY66505.1 - 3.2e-13 49.6 0.0 3.9e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Gal11_ABD1 PF18535.1 KIY66508.1 - 0.005 16.9 0.0 0.0061 16.6 0.0 1.1 1 0 0 1 1 1 1 Gal11 activator-binding domain (ABD1) Phage_holin_5_2 PF16079.5 KIY66509.1 - 0.07 13.5 1.9 4.6 7.6 0.0 2.6 1 1 0 2 2 2 0 Phage holin family Hol44, in holin superfamily V Pheromone PF08015.11 KIY66511.1 - 0.3 12.2 2.2 11 7.2 2.2 2.4 1 1 0 1 1 1 0 Fungal mating-type pheromone STE3 PF02076.15 KIY66513.1 - 8.9e-102 340.2 23.5 1.1e-101 339.9 23.5 1.1 1 0 0 1 1 1 1 Pheromone A receptor Glucan_synthase PF02364.15 KIY66513.1 - 0.25 9.4 2.2 0.39 8.8 2.2 1.2 1 0 0 1 1 1 0 1,3-beta-glucan synthase component Abhydrolase_9_N PF15420.6 KIY66513.1 - 2.3 8.2 11.1 0.23 11.5 0.4 3.1 2 1 1 3 3 3 0 Alpha/beta-hydrolase family N-terminus DUF4510 PF14971.6 KIY66514.1 - 0.18 12.1 0.7 0.28 11.5 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4510) BCS1_N PF08740.11 KIY66516.1 - 7.9e-45 153.1 4.4 7.9e-45 153.1 4.4 2.9 4 0 0 4 4 3 1 BCS1 N terminal AAA PF00004.29 KIY66516.1 - 2.3e-14 53.9 0.0 8.3e-07 29.5 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 KIY66516.1 - 0.00094 18.4 0.0 0.0018 17.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_29 PF13555.6 KIY66516.1 - 0.0026 17.4 0.0 0.018 14.8 0.0 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 KIY66516.1 - 0.005 17.2 3.3 0.0078 16.6 0.1 2.7 2 1 0 2 2 2 1 AAA ATPase domain Viral_helicase1 PF01443.18 KIY66516.1 - 0.0051 16.6 0.1 0.012 15.4 0.0 1.7 1 1 0 1 1 1 1 Viral (Superfamily 1) RNA helicase SR-25 PF10500.9 KIY66516.1 - 0.0086 15.7 6.9 0.0086 15.7 6.9 4.1 4 0 0 4 4 3 1 Nuclear RNA-splicing-associated protein CPSF100_C PF13299.6 KIY66516.1 - 0.0093 16.2 10.1 0.037 14.2 3.3 2.6 3 0 0 3 3 2 1 Cleavage and polyadenylation factor 2 C-terminal MITF_TFEB_C_3_N PF15951.5 KIY66516.1 - 0.033 14.8 4.0 0.098 13.3 4.0 1.9 1 0 0 1 1 1 0 MITF/TFEB/TFEC/TFE3 N-terminus Rrn6 PF10214.9 KIY66516.1 - 0.034 12.6 12.5 0.027 13.0 8.8 2.1 2 0 0 2 2 2 0 RNA polymerase I-specific transcription-initiation factor Ferlin_C PF16165.5 KIY66516.1 - 0.049 13.6 4.1 1.6 8.7 1.9 2.3 2 0 0 2 2 2 0 Ferlin C-terminus ABC_tran PF00005.27 KIY66516.1 - 0.073 13.6 1.2 0.17 12.4 0.0 2.1 2 0 0 2 2 2 0 ABC transporter GAGA_bind PF06217.12 KIY66516.1 - 0.077 13.3 2.3 0.41 10.9 2.2 2.0 2 0 0 2 2 2 0 GAGA binding protein-like family AAA_33 PF13671.6 KIY66516.1 - 0.17 12.1 0.0 0.17 12.1 0.0 2.4 2 0 0 2 2 1 0 AAA domain AAA_23 PF13476.6 KIY66516.1 - 0.46 11.0 9.0 13 6.2 0.0 3.0 3 0 0 3 3 3 0 AAA domain U1snRNP70_N PF12220.8 KIY66516.1 - 0.81 10.4 11.3 0.18 12.5 5.3 2.6 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal AAA_11 PF13086.6 KIY66516.1 - 1.2 8.9 7.6 6.9 6.4 1.3 2.9 2 1 1 3 3 3 0 AAA domain AAA_18 PF13238.6 KIY66516.1 - 1.3 9.6 6.4 1.9 9.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain BRF1 PF07741.13 KIY66516.1 - 2.1 8.8 14.1 1.5 9.2 7.6 2.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain Rtf2 PF04641.12 KIY66516.1 - 3.4 7.0 11.9 0.12 11.8 2.2 2.2 2 0 0 2 2 2 0 Rtf2 RING-finger AP3D1 PF06375.11 KIY66516.1 - 4.3 7.6 22.8 0.32 11.2 5.6 3.1 3 0 0 3 3 3 0 AP-3 complex subunit delta-1 ECH_1 PF00378.20 KIY66522.1 - 2.2e-20 73.0 0.2 3.4e-20 72.4 0.2 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KIY66522.1 - 1.8e-06 27.7 0.2 2.7e-06 27.1 0.2 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 KIY66522.1 - 0.0079 16.2 0.5 2.9 7.8 0.1 2.2 2 0 0 2 2 2 2 Peptidase family S49 ECH_1 PF00378.20 KIY66523.1 - 4.6e-21 75.3 0.0 6.6e-21 74.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KIY66523.1 - 4.7e-05 23.0 0.1 9.5e-05 22.0 0.0 1.5 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 KIY66523.1 - 0.11 12.4 0.4 0.38 10.7 0.1 1.8 2 0 0 2 2 2 0 Peptidase family S49 ABC_tran PF00005.27 KIY66524.1 - 1.2e-22 80.9 0.0 2.3e-22 80.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KIY66524.1 - 2.6e-05 23.8 0.1 0.058 12.8 0.1 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KIY66524.1 - 2.9e-05 24.0 0.0 0.00083 19.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KIY66524.1 - 0.00019 22.0 0.0 0.00042 20.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KIY66524.1 - 0.00021 21.0 0.0 0.00049 19.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KIY66524.1 - 0.0004 20.3 0.0 0.00084 19.3 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 KIY66524.1 - 0.00059 20.3 0.1 0.0025 18.2 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_15 PF13175.6 KIY66524.1 - 0.0016 18.3 0.0 0.0082 15.9 0.0 2.1 3 0 0 3 3 3 1 AAA ATPase domain MMR_HSR1 PF01926.23 KIY66524.1 - 0.0037 17.3 0.1 0.011 15.8 0.1 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 KIY66524.1 - 0.005 17.1 0.0 0.019 15.2 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KIY66524.1 - 0.015 15.5 0.0 0.034 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KIY66524.1 - 0.015 15.0 0.0 0.045 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain BLOC1_2 PF10046.9 KIY66524.1 - 0.017 15.4 0.0 0.037 14.3 0.0 1.5 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 KAP_NTPase PF07693.14 KIY66524.1 - 0.018 14.3 0.0 0.033 13.4 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain Ploopntkinase3 PF18751.1 KIY66524.1 - 0.028 14.3 0.0 0.053 13.4 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_14 PF13173.6 KIY66524.1 - 0.058 13.4 0.0 0.32 11.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain ABC_ATPase PF09818.9 KIY66524.1 - 0.072 11.9 0.0 0.27 10.0 0.0 1.8 2 0 0 2 2 2 0 Predicted ATPase of the ABC class Zeta_toxin PF06414.12 KIY66524.1 - 0.082 12.2 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.6 KIY66524.1 - 0.095 12.9 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Vut_1 PF02592.15 KIY66524.1 - 0.11 12.9 0.4 0.24 11.7 0.4 1.5 1 0 0 1 1 1 0 Putative vitamin uptake transporter FtsK_SpoIIIE PF01580.18 KIY66524.1 - 0.13 11.6 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Asp PF00026.23 KIY66525.1 - 2.4e-69 234.2 0.0 2.8e-69 234.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIY66525.1 - 2.2e-10 41.1 0.1 8.6e-08 32.6 0.1 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KIY66525.1 - 9.9e-05 22.9 0.3 3.4 8.4 0.0 3.5 3 0 0 3 3 3 2 Aspartyl protease Pkinase PF00069.25 KIY66526.1 - 1.1e-49 169.2 0.0 2.4e-49 168.1 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY66526.1 - 3.7e-19 69.0 0.0 7.9e-19 67.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 KIY66526.1 - 0.0099 15.5 0.2 0.03 13.9 0.2 1.8 1 1 0 1 1 1 1 RIO1 family IBP39 PF11422.8 KIY66526.1 - 0.16 11.8 0.1 1.9 8.2 0.0 2.2 2 0 0 2 2 2 0 Initiator binding protein 39 kDa CompInhib_SCIN PF11546.8 KIY66528.1 - 0.026 14.6 0.8 3.3 7.8 0.1 2.7 1 1 1 3 3 3 0 Staphylococcal complement inhibitor SCIN PPP4R2 PF09184.11 KIY66528.1 - 0.03 13.9 4.1 0.038 13.6 4.1 1.1 1 0 0 1 1 1 0 PPP4R2 Syntaxin_2 PF14523.6 KIY66528.1 - 0.2 12.0 4.8 1.3 9.5 0.5 2.3 1 1 1 2 2 2 0 Syntaxin-like protein ApoA-II PF04711.13 KIY66529.1 - 0.054 13.6 0.3 0.2 11.8 0.1 2.0 2 1 1 3 3 3 0 Apolipoprotein A-II (ApoA-II) DUF948 PF06103.11 KIY66529.1 - 0.08 13.2 0.2 3.7 7.9 0.2 2.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) PPP4R2 PF09184.11 KIY66529.1 - 0.17 11.5 4.2 0.21 11.1 4.2 1.1 1 0 0 1 1 1 0 PPP4R2 Syntaxin_2 PF14523.6 KIY66529.1 - 0.35 11.3 2.9 0.78 10.1 0.5 2.3 1 1 1 2 2 2 0 Syntaxin-like protein Ku_C PF03730.14 KIY66529.1 - 4.6 8.0 6.7 1.7 9.4 2.5 2.3 1 1 2 3 3 3 0 Ku70/Ku80 C-terminal arm CRF1 PF10380.9 KIY66530.1 - 0.054 13.8 0.4 0.5 10.7 0.0 2.1 2 0 0 2 2 2 0 Transcription factor CRF1 Bindin PF02084.15 KIY66531.1 - 0.01 16.1 5.5 0.013 15.8 5.5 1.2 1 0 0 1 1 1 0 Bindin Med15 PF09606.10 KIY66531.1 - 0.83 8.3 17.2 0.87 8.2 17.2 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Pyr_redox_2 PF07992.14 KIY66532.1 - 1.1e-46 159.4 6.3 1.5e-46 159.0 6.3 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 KIY66532.1 - 8.4e-17 60.9 0.0 1.9e-16 59.7 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Reductase_C PF14759.6 KIY66532.1 - 5.5e-10 39.7 0.0 1.6e-09 38.2 0.0 1.8 1 0 0 1 1 1 1 Reductase C-terminal Pyr_redox PF00070.27 KIY66532.1 - 3.8e-09 37.0 2.5 3.8e-09 37.0 2.5 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KIY66532.1 - 3e-07 30.0 2.8 3e-07 30.0 2.8 1.7 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KIY66532.1 - 1e-05 24.8 0.4 0.057 12.5 0.1 2.6 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Rieske_2 PF13806.6 KIY66532.1 - 1.1e-05 25.3 0.0 2.8e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain HI0933_like PF03486.14 KIY66532.1 - 0.00021 20.1 0.4 0.43 9.2 0.0 3.0 3 0 0 3 3 3 2 HI0933-like protein DAO PF01266.24 KIY66532.1 - 0.00023 20.9 0.4 0.38 10.3 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.24 KIY66532.1 - 0.0004 19.8 0.7 0.071 12.4 0.1 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 KIY66532.1 - 0.0012 18.9 2.5 3.7 7.5 0.1 3.3 3 0 0 3 3 3 2 FAD-NAD(P)-binding IMS PF00817.20 KIY66533.1 - 9.1e-42 142.6 0.0 1.5e-41 141.9 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 KIY66533.1 - 1.1e-14 55.1 0.0 1.8e-13 51.2 0.0 2.5 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain zf_UBZ PF18439.1 KIY66533.1 - 8.8e-07 28.4 3.4 0.00052 19.6 0.7 2.4 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger IMS_HHH PF11798.8 KIY66533.1 - 0.025 14.9 0.0 0.069 13.5 0.0 1.8 1 0 0 1 1 1 0 IMS family HHH motif 7tm_1 PF00001.21 KIY66534.1 - 1.3e-06 28.0 5.6 1.4e-06 27.9 4.6 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) TRAP_alpha PF03896.16 KIY66535.1 - 0.00046 19.5 0.0 0.00062 19.1 0.0 1.2 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit MitoNEET_N PF10660.9 KIY66535.1 - 0.046 13.7 0.1 0.16 12.0 0.1 1.9 2 0 0 2 2 2 0 Iron-containing outer mitochondrial membrane protein N-terminus Ribosomal_L28e PF01778.17 KIY66536.1 - 1.8e-38 131.8 2.6 1.8e-38 131.8 2.6 1.9 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.14 KIY66536.1 - 1.1e-27 96.6 22.2 1.1e-27 96.6 22.2 2.6 1 1 1 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.10 KIY66536.1 - 0.00017 21.1 25.2 0.00024 20.6 25.2 1.2 1 0 0 1 1 1 1 BUD22 PYC_OADA PF02436.18 KIY66536.1 - 0.18 11.5 3.6 0.34 10.6 3.3 1.6 1 1 0 1 1 1 0 Conserved carboxylase domain BSP_II PF05432.11 KIY66536.1 - 0.78 9.4 21.3 1.1 8.9 21.3 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Nop14 PF04147.12 KIY66536.1 - 2.7 6.1 35.0 3.6 5.7 35.0 1.1 1 0 0 1 1 1 0 Nop14-like family TFIIF_alpha PF05793.12 KIY66536.1 - 2.7 6.5 35.4 3.8 6.0 35.4 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PI3K_1B_p101 PF10486.9 KIY66536.1 - 3 5.5 11.1 3.7 5.2 11.1 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit SAPS PF04499.15 KIY66536.1 - 7.6 5.2 11.8 11 4.7 11.8 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein COesterase PF00135.28 KIY66537.1 - 4.6e-53 180.9 0.0 6.1e-53 180.4 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KIY66537.1 - 5.4e-06 26.4 0.0 1.1e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thiolase_N PF00108.23 KIY66538.1 - 1.4e-12 47.5 1.0 4.8e-11 42.5 1.0 2.7 1 1 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KIY66538.1 - 8.3e-09 35.2 0.0 5.7e-08 32.4 0.0 2.3 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KIY66538.1 - 3.2e-06 26.9 1.8 0.029 14.0 0.6 2.5 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KIY66538.1 - 0.0025 17.6 0.5 0.15 11.9 0.1 2.7 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III IF3_C PF00707.22 KIY66539.1 - 0.00028 20.8 0.0 0.0007 19.5 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain Peptidase_M75 PF09375.10 KIY66539.1 - 0.0036 16.8 0.2 0.0043 16.6 0.2 1.2 1 0 0 1 1 1 1 Imelysin Amidase PF01425.21 KIY66539.1 - 0.0063 15.5 0.3 0.0079 15.2 0.3 1.1 1 0 0 1 1 1 1 Amidase PPR_2 PF13041.6 KIY66540.1 - 2.9e-07 30.5 0.1 0.0056 16.9 0.0 4.6 5 1 0 5 5 5 2 PPR repeat family PPR_3 PF13812.6 KIY66540.1 - 0.00019 21.5 0.3 0.00069 19.6 0.0 2.1 2 0 0 2 2 2 1 Pentatricopeptide repeat domain PPR PF01535.20 KIY66540.1 - 0.00068 19.7 0.7 4.7 7.7 0.0 4.4 4 0 0 4 4 4 1 PPR repeat PPR_1 PF12854.7 KIY66540.1 - 0.002 17.8 0.0 0.02 14.6 0.0 2.6 3 0 0 3 3 3 1 PPR repeat HCMVantigenic_N PF12154.8 KIY66540.1 - 0.29 11.3 4.7 0.17 12.0 2.2 2.0 2 0 0 2 2 2 0 Glycoprotein B N-terminal antigenic domain of HCMV 7tm_1 PF00001.21 KIY66541.1 - 1.3 8.3 7.3 1.6 7.9 7.3 1.4 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Acetyltransf_3 PF13302.7 KIY66542.1 - 1.4e-13 51.7 0.1 2e-13 51.2 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIY66542.1 - 6.5e-07 29.6 0.0 1.5e-06 28.4 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KIY66542.1 - 0.00014 22.2 0.0 0.00024 21.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIY66542.1 - 0.00065 19.6 0.0 0.0014 18.6 0.0 1.6 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 KIY66542.1 - 0.077 12.7 0.0 0.28 10.9 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain DUF1295 PF06966.12 KIY66543.1 - 1.7e-31 109.6 10.5 6.1e-31 107.7 8.6 2.5 1 1 1 2 2 2 1 Protein of unknown function (DUF1295) ICMT PF04140.14 KIY66543.1 - 0.047 14.1 0.0 0.38 11.2 0.0 2.5 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Sugar_tr PF00083.24 KIY66544.1 - 5.6e-56 190.3 17.8 7.2e-56 189.9 17.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY66544.1 - 2.1e-19 69.6 26.6 2.1e-19 69.6 26.6 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Complex1_LYR PF05347.15 KIY66545.1 - 1.2e-10 41.3 1.0 1.5e-10 40.9 0.1 1.7 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KIY66545.1 - 0.0043 17.8 0.5 0.0055 17.4 0.5 1.2 1 0 0 1 1 1 1 Complex1_LYR-like zf-C3HC PF07967.13 KIY66547.1 - 1.5e-28 99.5 0.0 4.5e-25 88.2 0.0 2.4 2 0 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.10 KIY66547.1 - 7e-16 58.2 0.4 2.3e-11 43.7 0.0 3.1 2 1 0 2 2 2 2 Rsm1-like DM PF00751.18 KIY66547.1 - 2.4 8.1 7.6 7 6.6 0.2 2.8 3 0 0 3 3 3 0 DM DNA binding domain Glyco_hydro_43 PF04616.14 KIY66548.1 - 3.3e-42 144.8 7.6 3.8e-42 144.6 7.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 DTW PF03942.15 KIY66548.1 - 0.11 12.2 0.1 0.15 11.7 0.1 1.3 1 1 0 1 1 1 0 DTW domain Oxidored_FMN PF00724.20 KIY66549.1 - 2e-98 329.8 0.0 2.2e-98 329.7 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family IML1 PF12257.8 KIY66550.1 - 1.2e-113 379.1 0.0 1.6e-113 378.6 0.0 1.2 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 KIY66550.1 - 1.9e-18 66.3 0.0 3.7e-18 65.3 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) ABC_tran PF00005.27 KIY66551.1 - 3e-21 76.4 0.0 4.6e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KIY66551.1 - 4.1e-07 30.1 0.3 0.00097 19.0 0.1 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KIY66551.1 - 0.0012 18.6 0.0 0.0025 17.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 KIY66551.1 - 0.0019 17.7 0.1 0.021 14.3 0.0 1.9 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain NACHT PF05729.12 KIY66551.1 - 0.0096 15.8 0.4 0.047 13.6 0.1 1.9 2 0 0 2 2 2 1 NACHT domain SbcCD_C PF13558.6 KIY66551.1 - 0.011 16.0 0.9 0.052 13.8 0.2 2.3 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 KIY66551.1 - 0.011 15.4 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KIY66551.1 - 0.015 15.7 0.2 0.02 15.3 0.2 1.5 1 1 0 1 1 1 0 AAA ATPase domain TsaE PF02367.17 KIY66551.1 - 0.045 13.7 0.0 0.095 12.7 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 KIY66551.1 - 0.083 13.2 0.2 0.21 11.9 0.2 1.8 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KIY66551.1 - 0.13 12.1 0.1 0.21 11.5 0.1 1.3 1 0 0 1 1 1 0 RsgA GTPase NB-ARC PF00931.22 KIY66551.1 - 0.14 11.3 0.0 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain ABC_ATPase PF09818.9 KIY66551.1 - 0.25 10.1 0.3 8.5 5.0 0.0 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class Nucleoporin_FG PF13634.6 KIY66552.1 - 7.3e-06 26.7 33.9 7.4e-05 23.5 16.9 15.4 4 2 6 10 10 10 3 Nucleoporin FG repeat region ANAPC4_WD40 PF12894.7 KIY66552.1 - 0.00021 21.5 0.0 0.0036 17.6 0.0 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain NUP214 PF16755.5 KIY66552.1 - 0.063 12.5 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 TAF6_C PF07571.13 KIY66553.1 - 1.9e-16 60.2 0.1 4.8e-16 58.9 0.1 1.6 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 KIY66553.1 - 2.2e-15 56.6 0.2 4e-15 55.7 0.2 1.4 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 KIY66553.1 - 0.0003 21.2 0.4 0.00059 20.2 0.4 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 KIY66553.1 - 0.021 14.8 0.0 0.054 13.5 0.0 1.6 1 0 0 1 1 1 0 Bromodomain associated RITA PF17066.5 KIY66553.1 - 0.032 13.8 0.3 0.055 13.1 0.3 1.3 1 0 0 1 1 1 0 RBPJ-interacting and tubulin associated protein CBFD_NFYB_HMF PF00808.23 KIY66553.1 - 0.18 12.1 0.1 0.41 11.0 0.1 1.7 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone NAD_binding_10 PF13460.6 KIY66554.1 - 0.033 14.1 0.0 0.057 13.3 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding GPI-anchored PF10342.9 KIY66555.1 - 8.5e-08 32.9 0.1 8.5e-08 32.9 0.1 2.0 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family AIF_C PF14721.6 KIY66555.1 - 0.0017 18.7 0.1 0.0024 18.2 0.1 1.2 1 0 0 1 1 1 1 Apoptosis-inducing factor, mitochondrion-associated, C-term SSP160 PF06933.11 KIY66555.1 - 0.091 11.0 17.4 0.12 10.6 17.4 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF515 PF04415.12 KIY66555.1 - 6.7 5.0 12.9 8.8 4.6 12.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) SH3_9 PF14604.6 KIY66556.1 - 6.8e-14 51.5 0.0 1.2e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KIY66556.1 - 2.9e-13 49.2 0.1 4.5e-13 48.6 0.1 1.2 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KIY66556.1 - 1.4e-11 43.9 0.0 2.2e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Pex14_N PF04695.13 KIY66556.1 - 2.1 9.0 12.4 0.35 11.5 6.2 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Abhydrolase_1 PF00561.20 KIY66558.1 - 6.9e-17 61.9 0.3 1.3e-13 51.2 0.2 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIY66558.1 - 6.5e-14 53.1 0.0 8e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIY66558.1 - 7.4e-10 38.5 0.0 1.4e-09 37.6 0.0 1.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 KIY66558.1 - 0.00095 19.1 0.0 0.011 15.7 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 KIY66558.1 - 0.012 15.7 0.0 0.021 14.9 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein Esterase PF00756.20 KIY66558.1 - 0.048 13.3 0.0 0.13 11.9 0.0 1.6 2 0 0 2 2 2 0 Putative esterase DNA_primase_S PF01896.19 KIY66559.1 - 5.6e-48 163.3 0.0 7.5e-48 162.9 0.0 1.2 1 0 0 1 1 1 1 DNA primase small subunit Stealth_CR4 PF17103.5 KIY66559.1 - 0.11 12.4 0.1 0.35 10.8 0.1 1.8 1 0 0 1 1 1 0 Stealth protein CR4, conserved region 4 AA_permease PF00324.21 KIY66560.1 - 1e-122 410.2 40.2 1.1e-122 410.0 40.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KIY66560.1 - 2.5e-30 105.7 45.9 3.5e-30 105.2 45.9 1.1 1 0 0 1 1 1 1 Amino acid permease DnaJ PF00226.31 KIY66561.1 - 1.4e-21 76.4 1.8 2.9e-21 75.4 1.8 1.5 1 0 0 1 1 1 1 DnaJ domain Epimerase PF01370.21 KIY66562.1 - 2.7e-15 56.5 0.0 4e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KIY66562.1 - 5e-10 39.6 0.0 1.3e-09 38.2 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KIY66562.1 - 4.4e-08 32.5 0.0 5.6e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KIY66562.1 - 0.0001 21.6 0.0 0.0071 15.5 0.0 2.3 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.13 KIY66562.1 - 0.00037 20.1 0.3 0.00093 18.8 0.2 1.7 2 0 0 2 2 2 1 NmrA-like family GDP_Man_Dehyd PF16363.5 KIY66562.1 - 0.0039 16.6 0.0 0.013 14.9 0.1 1.8 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 KIY66562.1 - 0.082 12.4 0.4 0.15 11.5 0.1 1.7 2 0 0 2 2 2 0 short chain dehydrogenase ubiquitin PF00240.23 KIY66563.1 - 2.7e-34 116.8 0.4 3e-34 116.6 0.4 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KIY66563.1 - 5.1e-15 55.1 0.3 5.7e-15 54.9 0.3 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KIY66563.1 - 6.9e-06 26.4 0.1 3.1e-05 24.3 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 KIY66563.1 - 0.0019 18.1 0.0 0.0022 17.9 0.0 1.2 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 KIY66563.1 - 0.002 18.5 0.1 0.0022 18.3 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 KIY66563.1 - 0.0031 17.6 0.1 0.0072 16.4 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 KIY66563.1 - 0.018 15.1 0.2 2.5 8.2 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin-like domain DUF2407 PF10302.9 KIY66563.1 - 0.02 15.5 0.1 0.023 15.2 0.1 1.1 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain LysM PF01476.20 KIY66564.1 - 5.1e-09 36.1 0.0 7.3e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 LysM domain Actino_peptide PF14408.6 KIY66564.1 - 0.04 14.0 0.0 0.084 13.0 0.0 1.5 1 0 0 1 1 1 0 Ribosomally synthesised peptide in actinomycetes DUF903 PF06004.12 KIY66564.1 - 0.16 11.9 0.2 0.48 10.4 0.3 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF903) F-box PF00646.33 KIY66567.1 - 1.5e-06 27.9 0.3 3e-06 27.0 0.3 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KIY66567.1 - 0.0019 18.0 0.4 0.004 17.0 0.4 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY66568.1 - 0.027 14.4 0.4 0.056 13.3 0.4 1.5 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 KIY66568.1 - 0.033 14.1 0.5 0.08 12.9 0.5 1.7 1 0 0 1 1 1 0 F-box-like F-box_4 PF15966.5 KIY66568.1 - 0.08 12.8 0.1 0.17 11.8 0.1 1.4 1 0 0 1 1 1 0 F-box F-box PF00646.33 KIY66569.1 - 3.4e-06 26.8 2.6 7.3e-06 25.7 2.6 1.6 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KIY66569.1 - 0.0029 17.5 0.1 0.0077 16.1 0.1 1.8 1 0 0 1 1 1 1 F-box Man-6-P_recep PF02157.15 KIY66569.1 - 0.029 13.5 0.6 0.052 12.6 0.6 1.4 1 0 0 1 1 1 0 Mannose-6-phosphate receptor F-box-like PF12937.7 KIY66569.1 - 0.029 14.2 4.0 0.03 14.2 0.5 2.4 2 1 1 3 3 3 0 F-box-like UxaC PF02614.14 KIY66569.1 - 0.031 13.1 0.7 0.044 12.6 0.7 1.1 1 0 0 1 1 1 0 Glucuronate isomerase NTP_transferase PF00483.23 KIY66570.1 - 1.2e-41 142.9 0.0 4.4e-41 141.1 0.0 1.8 2 0 0 2 2 2 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 KIY66570.1 - 2.2e-07 31.3 0.0 5.1e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 MobA-like NTP transferase domain MannoseP_isomer PF01050.18 KIY66570.1 - 0.00071 19.5 0.0 0.0012 18.7 0.0 1.4 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase DUF364 PF04016.12 KIY66570.1 - 0.016 14.8 0.0 0.034 13.7 0.0 1.5 1 0 0 1 1 1 0 Putative heavy-metal chelation Herpes_IE68 PF02479.16 KIY66570.1 - 0.13 11.9 0.0 1.9 8.1 0.0 2.2 2 0 0 2 2 2 0 Herpesvirus immediate early protein F-box-like PF12937.7 KIY66572.1 - 5.5e-07 29.4 0.7 3e-06 27.0 0.7 2.3 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KIY66572.1 - 0.0046 16.8 1.8 2.5 8.1 0.0 3.7 3 0 0 3 3 3 1 F-box domain DUF4250 PF14056.6 KIY66572.1 - 0.049 13.6 0.1 0.13 12.2 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4250) DivIC PF04977.15 KIY66572.1 - 0.14 12.0 0.5 0.27 11.0 0.5 1.4 1 0 0 1 1 1 0 Septum formation initiator Metallophos PF00149.28 KIY66574.1 - 4.3e-07 30.6 0.5 6.7e-06 26.7 0.5 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KIY66574.1 - 5.6e-07 29.9 0.1 2.4e-05 24.6 0.1 2.7 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Lactamase_B_3 PF13483.6 KIY66574.1 - 0.02 14.8 0.0 1.1 9.2 0.0 2.2 2 0 0 2 2 2 0 Beta-lactamase superfamily domain DUF1899 PF08953.11 KIY66575.1 - 3.4e-27 94.1 0.1 6.4e-27 93.2 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 KIY66575.1 - 3.1e-17 62.2 0.2 7.6e-17 60.9 0.2 1.7 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 KIY66575.1 - 4.3e-12 46.3 8.5 0.003 18.3 0.3 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY66575.1 - 5.5e-08 33.0 0.2 0.0047 17.2 0.0 4.1 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain VID27 PF08553.10 KIY66575.1 - 0.0046 16.1 0.1 0.011 14.9 0.0 1.5 2 0 0 2 2 2 1 VID27 C-terminal WD40-like domain APC_N_CC PF16689.5 KIY66575.1 - 0.021 14.9 0.5 0.042 13.9 0.5 1.4 1 0 0 1 1 1 0 Coiled-coil N-terminus of APC, dimerisation domain Ig_GlcNase PF18368.1 KIY66577.1 - 0.017 15.3 0.0 0.046 13.9 0.0 1.7 2 0 0 2 2 2 0 Exo-beta-D-glucosaminidase Ig-fold domain Homeodomain PF00046.29 KIY66578.1 - 1.6e-10 40.7 1.4 2.5e-10 40.0 1.4 1.3 1 0 0 1 1 1 1 Homeodomain DUF2152 PF10222.9 KIY66578.1 - 0.16 10.3 0.1 0.2 10.0 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2152) F-box-like PF12937.7 KIY66579.1 - 9.9e-06 25.4 0.0 4.7e-05 23.2 0.0 2.3 2 1 0 2 2 2 1 F-box-like F-box PF00646.33 KIY66579.1 - 0.069 13.1 0.0 15 5.6 0.0 2.9 2 0 0 2 2 2 0 F-box domain DisA-linker PF10635.9 KIY66579.1 - 0.079 12.7 0.1 0.22 11.3 0.1 1.7 2 0 0 2 2 2 0 DisA bacterial checkpoint controller linker region SlyX PF04102.12 KIY66579.1 - 0.092 13.4 3.6 0.13 12.9 0.3 2.5 2 0 0 2 2 2 0 SlyX Troponin PF00992.20 KIY66579.1 - 0.096 13.0 0.0 0.17 12.2 0.0 1.3 1 0 0 1 1 1 0 Troponin Fanconi_A_N PF15865.5 KIY66579.1 - 0.13 11.6 0.4 0.29 10.5 0.1 1.7 2 0 0 2 2 2 0 Fanconi anaemia group A protein N terminus DUF1269 PF06897.12 KIY66579.1 - 0.2 11.9 0.1 0.78 10.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1269) YjcZ PF13990.6 KIY66579.1 - 0.88 8.9 3.3 7.6 5.8 0.3 2.1 1 1 1 2 2 2 0 YjcZ-like protein F-box-like PF12937.7 KIY66581.1 - 2.4e-06 27.3 0.0 0.00012 21.9 0.0 3.1 2 1 0 2 2 2 1 F-box-like F-box PF00646.33 KIY66581.1 - 0.076 12.9 0.1 16 5.5 0.0 2.9 2 0 0 2 2 2 0 F-box domain CBM_21 PF03370.13 KIY66583.1 - 7e-26 90.6 0.0 1.1e-25 89.9 0.0 1.3 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 KIY66583.1 - 1.4e-07 32.0 0.1 2.7e-07 31.1 0.1 1.4 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) DUF3402 PF11882.8 KIY66583.1 - 2.2 7.3 3.9 15 4.6 0.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3402) HSF_DNA-bind PF00447.17 KIY66584.1 - 1e-31 109.4 2.8 2.7e-31 108.1 1.4 2.2 2 0 0 2 2 2 1 HSF-type DNA-binding Response_reg PF00072.24 KIY66584.1 - 9.1e-26 90.2 0.2 1.2e-24 86.7 0.2 2.7 2 0 0 2 2 2 1 Response regulator receiver domain Leu_zip PF15294.6 KIY66584.1 - 0.0045 16.5 0.1 0.0084 15.7 0.1 1.4 1 0 0 1 1 1 1 Leucine zipper EzrA PF06160.12 KIY66584.1 - 0.042 12.0 0.0 0.068 11.3 0.0 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Fungal_trans PF04082.18 KIY66585.1 - 6.7e-19 67.9 0.0 2.5e-18 66.1 0.0 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY66585.1 - 3.6e-07 30.2 10.5 5.7e-07 29.5 10.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugarporin_N PF11471.8 KIY66585.1 - 0.027 14.4 0.0 0.063 13.3 0.0 1.5 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension zf-4CXXC_R1 PF10497.9 KIY66586.1 - 1.6e-14 53.9 29.0 3.1e-08 33.8 8.6 2.4 2 0 0 2 2 2 2 Zinc-finger domain of monoamine-oxidase A repressor R1 tRNA_int_endo PF01974.17 KIY66587.1 - 3.8e-12 46.1 0.0 6.5e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain MmcB-like PF06319.12 KIY66587.1 - 0.092 12.4 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 DNA repair protein MmcB-like DUF4407 PF14362.6 KIY66587.1 - 1.5 8.1 9.2 2.1 7.6 9.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PIEZO PF15917.5 KIY66587.1 - 3.5 7.1 5.7 4.8 6.6 5.7 1.1 1 0 0 1 1 1 0 Piezo NAD_binding_10 PF13460.6 KIY66588.1 - 4e-11 43.1 0.1 6.6e-11 42.4 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KIY66588.1 - 2.4e-10 40.4 0.1 4.1e-10 39.6 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 KIY66588.1 - 0.00014 22.2 0.1 0.00029 21.1 0.1 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KIY66588.1 - 0.00016 21.2 0.0 0.002 17.7 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KIY66588.1 - 0.00026 20.3 0.0 0.04 13.1 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein DapB_N PF01113.20 KIY66588.1 - 0.0046 17.1 0.1 0.008 16.3 0.1 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus 3Beta_HSD PF01073.19 KIY66588.1 - 0.0058 15.7 0.1 0.013 14.5 0.1 1.6 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 KIY66588.1 - 0.0079 16.6 0.0 0.017 15.5 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KIY66588.1 - 0.015 15.4 0.1 0.029 14.4 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase MM_CoA_mutase PF01642.22 KIY66588.1 - 0.059 11.9 0.1 3.8 5.9 0.0 2.1 2 0 0 2 2 2 0 Methylmalonyl-CoA mutase Peptidase_M20 PF01546.28 KIY66589.1 - 1.4e-33 116.3 0.0 2.1e-33 115.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KIY66589.1 - 4.6e-12 45.8 0.8 1.6e-11 44.1 0.8 1.9 1 1 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KIY66589.1 - 0.0015 18.2 0.0 0.0028 17.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 zf-C2H2 PF00096.26 KIY66591.1 - 5e-06 26.7 28.3 0.026 15.0 0.2 5.7 6 0 0 6 6 6 3 Zinc finger, C2H2 type OrsD PF12013.8 KIY66591.1 - 5.1e-06 26.9 4.7 0.92 10.0 0.3 3.6 3 0 0 3 3 3 3 Orsellinic acid/F9775 biosynthesis cluster protein D zf-H2C2_2 PF13465.6 KIY66591.1 - 0.024 15.0 0.5 0.024 15.0 0.5 5.2 5 0 0 5 5 5 0 Zinc-finger double domain FOXP-CC PF16159.5 KIY66591.1 - 0.027 15.1 9.9 2.6 8.7 0.2 3.8 1 1 2 3 3 3 0 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 KIY66591.1 - 0.04 14.8 20.7 1.5 9.8 0.0 5.4 5 0 0 5 5 5 0 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KIY66591.1 - 0.16 12.3 11.8 0.083 13.2 1.6 3.5 2 2 1 3 3 3 0 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 KIY66591.1 - 5.9 7.3 0.0 5.9 7.3 0.0 3.8 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 KIY66593.1 - 1.3e-06 28.6 29.9 0.0083 16.5 0.1 6.1 6 0 0 6 6 6 3 Zinc-finger double domain zf-C2H2 PF00096.26 KIY66593.1 - 1e-05 25.7 35.0 0.018 15.5 0.7 6.5 6 0 0 6 6 6 3 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 KIY66593.1 - 0.00028 20.6 29.5 0.00066 19.4 0.0 4.8 5 0 0 5 5 5 2 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 KIY66593.1 - 0.0023 18.6 37.8 0.59 11.1 1.0 6.3 6 0 0 6 6 6 3 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 KIY66593.1 - 0.088 12.9 5.2 14 5.8 0.0 3.2 2 1 1 3 3 3 0 Aberrant zinc-finger OrsD PF12013.8 KIY66593.1 - 0.09 13.2 19.9 3.8 8.0 0.1 5.3 3 1 2 5 5 5 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2HE PF16278.5 KIY66593.1 - 1.3 9.6 10.6 1.2 9.6 4.5 3.1 3 0 0 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf_C2H2_ZHX PF18387.1 KIY66593.1 - 4.4 7.0 17.2 6.5 6.5 0.7 4.5 3 2 1 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain FOXP-CC PF16159.5 KIY66593.1 - 7.1 7.3 13.0 26 5.5 1.6 3.8 2 1 1 3 3 3 0 FOXP coiled-coil domain zf-H2C2_2 PF13465.6 KIY66594.1 - 5.7e-08 32.8 34.3 0.015 15.7 1.0 7.2 7 1 0 7 7 7 4 Zinc-finger double domain zf-C2H2 PF00096.26 KIY66594.1 - 0.059 13.9 51.5 0.065 13.7 6.9 6.8 7 1 1 8 8 8 0 Zinc finger, C2H2 type FOXP-CC PF16159.5 KIY66594.1 - 0.52 11.0 0.1 0.52 11.0 0.1 4.6 4 1 2 6 6 6 0 FOXP coiled-coil domain DUF1936 PF09151.10 KIY66594.1 - 2.8 7.9 0.0 2.8 7.9 0.0 4.4 6 0 0 6 6 6 0 Domain of unknown function (DUF1936) SPX PF03105.19 KIY66594.1 - 6.5 6.6 11.8 10 5.9 11.8 1.2 1 0 0 1 1 1 0 SPX domain F-box-like PF12937.7 KIY66595.1 - 2.8e-05 23.9 0.1 0.0001 22.1 0.1 2.0 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KIY66597.1 - 9.1e-09 35.1 0.6 4.3e-08 32.9 0.1 2.4 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 KIY66597.1 - 0.05 13.5 0.1 0.67 9.9 0.1 2.8 1 1 0 1 1 1 0 F-box domain zf-H2C2_2 PF13465.6 KIY66598.1 - 9.9e-10 38.4 36.2 0.0011 19.3 0.1 7.1 7 0 0 7 7 7 4 Zinc-finger double domain zf-H2C2_5 PF13909.6 KIY66598.1 - 2.7e-06 27.0 24.3 0.00013 21.6 0.3 5.4 5 0 0 5 5 5 2 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 KIY66598.1 - 4.8e-06 26.7 34.9 0.2 12.2 0.1 6.3 6 0 0 6 6 6 4 Zinc finger, C2H2 type OrsD PF12013.8 KIY66598.1 - 0.0021 18.5 17.5 0.92 10.0 0.2 4.9 5 0 0 5 5 5 2 Orsellinic acid/F9775 biosynthesis cluster protein D zf_C2H2_ZHX PF18387.1 KIY66598.1 - 0.008 15.8 15.8 0.15 11.7 0.2 4.3 3 1 1 4 4 4 2 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_4 PF13894.6 KIY66598.1 - 0.2 12.6 35.5 7.4 7.7 0.2 6.6 6 0 0 6 6 6 0 C2H2-type zinc finger Sina PF03145.16 KIY66598.1 - 3.5 7.5 18.2 12 5.7 0.3 3.1 2 1 1 3 3 3 0 Seven in absentia protein family zf-C2HE PF16278.5 KIY66598.1 - 7.9 7.0 12.2 1.6 9.3 4.1 3.5 3 1 0 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-H2C2_5 PF13909.6 KIY66599.1 - 0.0009 18.9 18.4 0.019 14.7 1.2 4.3 4 0 0 4 4 4 3 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 KIY66599.1 - 0.014 15.8 33.1 0.042 14.3 1.4 5.8 6 0 0 6 6 6 0 Zinc finger, C2H2 type FOXP-CC PF16159.5 KIY66599.1 - 0.021 15.5 10.2 1.1 9.9 3.1 4.0 1 1 2 3 3 3 0 FOXP coiled-coil domain OrsD PF12013.8 KIY66599.1 - 2.3 8.7 15.2 4.8 7.7 0.1 4.7 4 1 0 5 5 5 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-MYND PF01753.18 KIY66600.1 - 3.1e-09 36.8 14.0 4.8e-09 36.1 14.0 1.3 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KIY66600.1 - 0.0055 17.0 12.3 0.01 16.1 12.3 1.4 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding PolC_DP2 PF03833.13 KIY66600.1 - 0.007 14.3 0.3 0.019 12.8 0.4 1.6 2 0 0 2 2 2 1 DNA polymerase II large subunit DP2 SPO22 PF08631.10 KIY66602.1 - 0.00039 20.0 0.6 0.00057 19.5 0.6 1.2 1 0 0 1 1 1 1 Meiosis protein SPO22/ZIP4 like TPR_19 PF14559.6 KIY66602.1 - 0.011 16.2 0.6 0.033 14.7 0.6 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat CPSase_L_D3 PF02787.19 KIY66602.1 - 0.05 14.0 0.1 0.086 13.2 0.1 1.5 1 0 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain FAM176 PF14851.6 KIY66602.1 - 0.086 12.5 2.0 0.16 11.7 2.0 1.5 1 0 0 1 1 1 0 FAM176 family TPR_14 PF13428.6 KIY66602.1 - 4.7 8.3 6.2 1.8 9.6 0.6 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-H2C2_2 PF13465.6 KIY66606.1 - 0.00015 22.0 1.0 0.00015 22.0 1.0 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-H2C2_5 PF13909.6 KIY66606.1 - 0.0031 17.2 10.2 0.27 11.0 0.1 3.5 3 0 0 3 3 3 2 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 KIY66606.1 - 0.11 13.0 0.7 0.11 13.0 0.7 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIY66606.1 - 0.61 11.1 15.5 0.42 11.6 0.6 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-UBP PF02148.19 KIY66606.1 - 1.5 9.2 5.8 8 6.9 0.6 2.4 1 1 1 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein ORC6 PF05460.13 KIY66607.1 - 0.14 11.4 4.2 0.2 10.9 4.2 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) bZIP_1 PF00170.21 KIY66609.1 - 2.3e-06 27.6 7.4 0.00038 20.5 2.9 2.2 2 0 0 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.15 KIY66609.1 - 0.0031 17.6 2.6 0.0031 17.6 2.6 2.5 3 0 0 3 3 3 2 Basic region leucine zipper YabA PF06156.13 KIY66609.1 - 0.15 12.7 0.0 0.25 12.0 0.0 1.4 1 0 0 1 1 1 0 Initiation control protein YabA Shugoshin_N PF07558.11 KIY66609.1 - 0.39 10.6 2.2 2.6 8.0 0.8 2.2 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region F-box-like PF12937.7 KIY66610.1 - 4.3e-07 29.7 0.2 1.6e-06 27.9 0.2 2.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY66610.1 - 0.015 15.2 0.1 0.14 12.1 0.1 2.5 1 1 0 1 1 1 0 F-box domain FlxA PF14282.6 KIY66610.1 - 0.026 14.5 0.1 0.043 13.8 0.1 1.2 1 0 0 1 1 1 0 FlxA-like protein DUF5082 PF16888.5 KIY66610.1 - 0.14 12.4 0.5 0.27 11.5 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) NPV_P10 PF05531.12 KIY66610.1 - 0.27 11.7 1.1 0.66 10.5 1.1 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein F-box-like PF12937.7 KIY66611.1 - 2.4e-06 27.3 0.7 8.2e-06 25.6 0.7 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY66611.1 - 4.3e-05 23.3 0.3 0.00084 19.2 0.3 2.6 1 1 0 1 1 1 1 F-box domain HTH_21 PF13276.6 KIY66612.1 - 0.06 13.5 0.9 0.14 12.3 0.9 1.6 1 0 0 1 1 1 0 HTH-like domain Peptidase_Mx PF15887.5 KIY66612.1 - 0.063 12.7 0.1 0.11 11.9 0.1 1.4 1 0 0 1 1 1 0 Putative zinc-binding metallo-peptidase HAMP PF00672.25 KIY66612.1 - 0.18 12.2 0.1 0.34 11.3 0.1 1.5 1 0 0 1 1 1 0 HAMP domain Alpha_kinase PF02816.18 KIY66613.1 - 2.2e-09 37.7 0.0 2.7e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 Alpha-kinase family Hamartin PF04388.12 KIY66615.1 - 0.087 11.5 13.9 0.13 10.9 13.9 1.2 1 0 0 1 1 1 0 Hamartin protein Metal_resist PF13801.6 KIY66615.1 - 1.8 8.8 9.3 5.9 7.1 9.3 1.9 1 0 0 1 1 1 0 Heavy-metal resistance F-box-like PF12937.7 KIY66616.1 - 5.6e-07 29.4 0.3 1.9e-06 27.7 0.3 2.0 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KIY66616.1 - 0.0066 16.3 0.7 0.12 12.3 0.7 2.6 1 1 0 1 1 1 1 F-box domain PAS_9 PF13426.7 KIY66617.1 - 3.4e-25 88.3 0.0 4.2e-17 62.3 0.0 2.1 2 0 0 2 2 2 2 PAS domain PAS_3 PF08447.12 KIY66617.1 - 7e-20 71.1 0.0 6.2e-13 48.8 0.0 3.0 2 1 0 2 2 2 2 PAS fold PAS PF00989.25 KIY66617.1 - 5.3e-16 58.6 0.0 6.9e-09 35.7 0.0 2.6 2 1 0 2 2 2 2 PAS fold PAS_4 PF08448.10 KIY66617.1 - 4.1e-08 33.4 0.0 0.0011 19.3 0.0 2.8 2 2 0 2 2 2 2 PAS fold PAS_8 PF13188.7 KIY66617.1 - 1.8e-07 31.0 0.0 0.0025 17.8 0.0 2.3 2 0 0 2 2 2 2 PAS domain PAS_11 PF14598.6 KIY66617.1 - 2.5e-05 24.4 0.0 4.6e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 PAS domain F-box-like PF12937.7 KIY66618.1 - 2e-08 34.0 0.1 4.4e-08 32.9 0.1 1.6 1 0 0 1 1 1 1 F-box-like FlxA PF14282.6 KIY66618.1 - 0.00076 19.4 0.3 0.0012 18.8 0.3 1.2 1 0 0 1 1 1 1 FlxA-like protein F-box PF00646.33 KIY66618.1 - 0.023 14.6 0.1 4.7 7.2 0.0 2.6 2 0 0 2 2 2 0 F-box domain CENP-F_leu_zip PF10473.9 KIY66618.1 - 0.067 13.2 0.3 0.13 12.3 0.3 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3450 PF11932.8 KIY66618.1 - 0.097 12.0 0.1 0.15 11.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) AIP3 PF03915.13 KIY66618.1 - 0.32 10.1 0.5 0.45 9.6 0.5 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 GPI-anchored PF10342.9 KIY66619.1 - 4.8e-07 30.5 0.1 7.2e-07 29.9 0.1 1.3 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Arginase PF00491.21 KIY66621.1 - 5.1e-84 282.1 0.3 6.1e-84 281.8 0.3 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 KIY66621.1 - 0.026 14.7 0.2 0.042 14.1 0.2 1.2 1 0 0 1 1 1 0 UPF0489 domain OPT PF03169.15 KIY66622.1 - 2.5e-128 429.4 49.4 2.8e-128 429.2 49.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein PAP_assoc PF03828.19 KIY66623.1 - 5.9e-12 45.6 0.0 1.3e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KIY66623.1 - 0.00032 20.9 0.0 0.00083 19.6 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain Abhydrolase_3 PF07859.13 KIY66624.1 - 1.4e-48 165.5 0.2 6.7e-48 163.3 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KIY66624.1 - 2.8e-15 56.0 0.0 1.7e-14 53.5 0.0 1.9 1 1 0 1 1 1 1 Steryl acetyl hydrolase COesterase PF00135.28 KIY66624.1 - 0.0066 15.4 0.1 0.017 14.0 0.0 1.6 2 0 0 2 2 2 1 Carboxylesterase family Peptidase_S9 PF00326.21 KIY66624.1 - 0.024 14.1 0.0 0.046 13.2 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KIY66624.1 - 0.059 12.6 0.0 0.14 11.4 0.0 1.6 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Amidohydro_3 PF07969.11 KIY66625.1 - 4.6e-14 52.7 0.2 5.1e-06 26.2 0.0 2.5 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.20 KIY66625.1 - 3.7e-11 42.9 0.0 9.6e-07 28.4 0.0 2.5 2 0 0 2 2 2 2 Amidohydrolase family PD40 PF07676.12 KIY66625.1 - 7.3e-09 35.3 2.1 9.4e-06 25.4 0.1 3.9 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat MFS_1 PF07690.16 KIY66626.1 - 2.8e-30 105.4 42.7 2.8e-30 105.4 42.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Lipase_GDSL_2 PF13472.6 KIY66627.1 - 9.6e-16 58.7 0.4 1.2e-15 58.3 0.4 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KIY66627.1 - 1.5e-05 25.1 0.0 2.5e-05 24.3 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase RE_AccI PF09545.10 KIY66627.1 - 0.077 12.0 0.0 0.11 11.5 0.0 1.1 1 0 0 1 1 1 0 AccI restriction endonuclease HisG_C PF08029.11 KIY66627.1 - 0.079 13.1 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 HisG, C-terminal domain TENA_THI-4 PF03070.16 KIY66628.1 - 9.3e-07 28.9 0.0 3.2e-06 27.1 0.0 1.7 1 1 0 1 1 1 1 TENA/THI-4/PQQC family Abhydrolase_3 PF07859.13 KIY66629.1 - 3.3e-64 216.6 0.0 4.1e-64 216.3 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KIY66629.1 - 8.6e-09 34.8 0.2 3e-08 33.0 0.2 1.7 1 1 0 1 1 1 1 Carboxylesterase family Say1_Mug180 PF10340.9 KIY66629.1 - 0.00014 20.8 0.0 0.0002 20.4 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 KIY66629.1 - 0.0004 19.9 0.0 0.001 18.6 0.0 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 KIY66629.1 - 0.001 18.0 0.0 0.0015 17.5 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme APH PF01636.23 KIY66631.1 - 2.4e-09 37.5 0.0 4.6e-09 36.6 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KIY66631.1 - 0.032 13.8 0.0 0.05 13.2 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Ras PF00071.22 KIY66635.1 - 1.5e-52 177.5 0.0 1.7e-52 177.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIY66635.1 - 2.4e-19 69.7 0.0 3.4e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIY66635.1 - 1.6e-07 30.9 0.0 2.3e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family PET117 PF15786.5 KIY66635.1 - 0.045 14.0 0.0 0.068 13.4 0.0 1.3 1 0 0 1 1 1 0 PET assembly of cytochrome c oxidase, mitochondrial GTP_EFTU PF00009.27 KIY66635.1 - 0.064 12.8 0.0 0.48 9.9 0.0 2.2 1 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Rnk_N PF14760.6 KIY66635.1 - 0.077 13.5 2.1 0.26 11.8 0.4 2.1 2 0 0 2 2 2 0 Rnk N-terminus Pyr_redox_2 PF07992.14 KIY66636.1 - 5.4e-17 62.0 0.2 5.3e-08 32.4 0.1 2.6 1 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KIY66636.1 - 0.0028 16.8 0.0 0.007 15.5 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KIY66636.1 - 0.014 14.7 1.4 1 8.5 0.7 2.5 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIY66636.1 - 0.02 15.1 0.1 0.15 12.3 0.0 2.5 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KIY66636.1 - 0.034 14.2 0.1 3 7.8 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding DUF2345 PF10106.9 KIY66636.1 - 0.057 13.3 0.1 0.14 12.0 0.1 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2345) HI0933_like PF03486.14 KIY66636.1 - 0.12 11.0 0.2 0.53 8.9 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein DAO PF01266.24 KIY66636.1 - 0.23 11.0 3.5 0.66 9.5 0.6 2.5 2 1 1 3 3 3 0 FAD dependent oxidoreductase Acetyltransf_10 PF13673.7 KIY66638.1 - 5.5e-05 23.1 0.0 0.0001 22.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KIY66638.1 - 0.01 16.2 0.1 0.02 15.3 0.1 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIY66638.1 - 0.016 15.2 0.0 0.043 13.8 0.0 1.8 1 1 1 2 2 2 0 FR47-like protein Acetyltransf_1 PF00583.25 KIY66638.1 - 0.052 13.8 0.0 0.089 13.0 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.6 KIY66638.1 - 0.12 12.5 0.0 0.3 11.2 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DHHC PF01529.20 KIY66639.1 - 1.3e-33 115.9 10.2 1.3e-33 115.9 10.2 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ribosomal_L40e PF01020.17 KIY66639.1 - 0.015 15.2 2.1 0.037 13.9 2.1 1.6 1 0 0 1 1 1 0 Ribosomal L40e family Yip1 PF04893.17 KIY66639.1 - 0.26 11.0 9.9 1.5 8.5 4.9 2.4 2 0 0 2 2 2 0 Yip1 domain ESSS PF10183.9 KIY66639.1 - 0.32 11.2 0.7 0.64 10.3 0.7 1.5 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF1272 PF06906.11 KIY66639.1 - 8.4 6.6 11.1 0.35 11.0 5.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) Phosducin PF02114.16 KIY66640.1 - 6.7e-08 31.8 0.0 1e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Phosducin NmrA PF05368.13 KIY66644.1 - 1.9e-37 129.1 0.0 2.4e-37 128.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KIY66644.1 - 5.8e-11 42.6 0.0 8.5e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KIY66644.1 - 0.00087 18.8 0.0 0.0013 18.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KIY66644.1 - 0.023 13.7 0.0 0.033 13.2 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 KIY66644.1 - 0.11 13.0 0.1 0.19 12.1 0.1 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.13 KIY66645.1 - 4.1e-35 121.4 0.0 5e-35 121.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KIY66645.1 - 6.9e-14 52.2 0.1 1e-13 51.6 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KIY66645.1 - 2.4e-06 27.2 0.1 4.1e-06 26.4 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 KIY66645.1 - 0.00064 20.2 0.0 0.00097 19.6 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KIY66645.1 - 0.0014 17.7 0.0 0.002 17.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KIY66645.1 - 0.13 11.4 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Male sterility protein Biotin_lipoyl PF00364.22 KIY66646.1 - 5.7e-19 67.7 0.9 1.1e-18 66.8 0.9 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 KIY66646.1 - 6e-07 29.7 0.0 1.8e-06 28.1 0.0 1.9 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 KIY66646.1 - 0.00045 20.0 0.0 0.0058 16.4 0.0 2.4 2 0 0 2 2 2 1 Biotin-lipoyl like DUF1631 PF07793.11 KIY66646.1 - 0.035 12.5 1.7 0.046 12.2 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) Kdo PF06293.14 KIY66647.1 - 1e-07 31.5 0.0 5.8e-06 25.8 0.0 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIY66647.1 - 1.4e-06 28.4 0.0 0.00019 21.4 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family EcKinase PF02958.20 KIY66647.1 - 6e-06 25.8 0.0 7.6e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Pkinase PF00069.25 KIY66647.1 - 4.7e-05 22.9 0.0 6.5e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 KIY66647.1 - 0.0054 16.3 0.0 0.037 13.6 0.0 2.0 1 1 0 1 1 1 1 RIO1 family Pkinase_Tyr PF07714.17 KIY66647.1 - 0.052 12.8 0.0 0.072 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase zf-C2H2 PF00096.26 KIY66649.1 - 1e-09 38.3 12.9 7e-05 23.1 1.9 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIY66649.1 - 1.6e-05 25.3 12.0 0.0023 18.6 1.4 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KIY66649.1 - 0.00022 21.5 4.4 0.00022 21.5 4.4 3.2 3 0 0 3 3 3 1 Zinc-finger double domain FOXP-CC PF16159.5 KIY66649.1 - 0.00051 20.6 2.9 0.17 12.5 0.5 2.4 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 KIY66649.1 - 0.051 13.6 1.0 0.051 13.6 1.0 2.7 2 1 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 KIY66649.1 - 0.92 9.6 4.8 13 5.8 1.1 2.2 1 1 0 2 2 2 0 Aberrant zinc-finger zf-C2H2_11 PF16622.5 KIY66649.1 - 5.2 6.9 10.2 1.4 8.8 3.0 2.4 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-H2C2_5 PF13909.6 KIY66649.1 - 5.9 6.7 14.7 1.2 9.0 1.1 3.0 3 0 0 3 3 3 0 C2H2-type zinc-finger domain Rad1 PF02144.16 KIY66650.1 - 5.4e-74 248.7 0.0 6.2e-74 248.5 0.0 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Sterol-sensing PF12349.8 KIY66652.1 - 1.1e-33 116.3 5.0 2.5e-33 115.1 5.0 1.6 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 KIY66652.1 - 1.3e-10 40.1 3.0 1.8e-10 39.6 3.0 1.1 1 0 0 1 1 1 1 Patched family DUF2373 PF10180.9 KIY66653.1 - 0.029 14.2 0.1 0.06 13.2 0.1 1.6 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) ALIX_LYPXL_bnd PF13949.6 KIY66654.1 - 0.086 12.1 0.2 0.097 12.0 0.2 1.0 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV PCI PF01399.27 KIY66655.1 - 2.2e-23 82.7 0.0 2.1e-22 79.6 0.0 2.7 3 0 0 3 3 3 1 PCI domain Rpn3_C PF08375.11 KIY66655.1 - 7.1e-20 71.2 2.6 1e-19 70.7 0.8 2.3 2 0 0 2 2 2 1 Proteasome regulatory subunit C-terminal ATP-synt_10 PF05176.14 KIY66655.1 - 0.024 13.9 0.1 0.057 12.7 0.1 1.6 1 0 0 1 1 1 0 ATP10 protein TPR_2 PF07719.17 KIY66655.1 - 0.036 14.2 0.2 0.036 14.2 0.2 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 KIY66655.1 - 2 8.8 5.6 5.9 7.3 0.2 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 KIY66655.1 - 8.5 6.4 6.1 8.2 6.4 0.2 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat GWT1 PF06423.12 KIY66656.1 - 9.4e-41 139.4 1.3 1.6e-40 138.6 0.0 2.1 3 0 0 3 3 3 1 GWT1 Glyco_hydro_16 PF00722.21 KIY66657.1 - 1.8e-09 37.3 0.0 7.4e-09 35.3 0.0 2.0 2 1 1 3 3 3 1 Glycosyl hydrolases family 16 E1-E2_ATPase PF00122.20 KIY66658.1 - 5.5e-49 166.1 0.0 5.5e-49 166.1 0.0 2.8 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 KIY66658.1 - 1.3e-18 68.1 2.4 4.1e-18 66.4 2.4 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KIY66658.1 - 2e-12 46.6 0.1 5.7e-12 45.1 0.1 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KIY66658.1 - 0.00022 21.1 0.0 0.001 18.9 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KIY66658.1 - 0.0068 16.5 0.0 0.017 15.2 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) NAD_binding_10 PF13460.6 KIY66660.1 - 6.4e-05 22.9 0.0 0.38 10.6 0.0 3.1 2 1 0 2 2 2 2 NAD(P)H-binding adh_short PF00106.25 KIY66660.1 - 0.00015 21.3 0.0 0.00022 20.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIY66660.1 - 0.16 11.5 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Pox_A3L PF05288.11 KIY66660.1 - 0.17 11.9 0.0 0.37 10.8 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A3L Protein ADH_zinc_N PF00107.26 KIY66661.1 - 7.1e-12 45.4 1.7 8.7e-12 45.1 0.6 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIY66661.1 - 1.2e-09 38.0 0.0 6e-09 35.8 0.0 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KIY66661.1 - 5.2e-05 24.3 0.0 8.4e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NMD3 PF04981.13 KIY66662.1 - 8e-80 267.8 0.4 1.1e-79 267.3 0.4 1.2 1 0 0 1 1 1 1 NMD3 family NinF PF05810.12 KIY66662.1 - 0.023 14.6 1.0 0.066 13.1 0.3 2.1 2 0 0 2 2 2 0 NinF protein DZR PF12773.7 KIY66662.1 - 0.083 12.9 8.0 2.4 8.3 8.4 2.6 1 1 0 1 1 1 0 Double zinc ribbon FAD_binding_3 PF01494.19 KIY66663.1 - 9.1e-20 71.2 0.0 1.6e-19 70.4 0.0 1.3 1 1 0 1 1 1 1 FAD binding domain SE PF08491.10 KIY66663.1 - 0.0064 15.6 0.0 0.41 9.6 0.0 2.4 2 0 0 2 2 2 2 Squalene epoxidase NAD_binding_8 PF13450.6 KIY66663.1 - 0.035 14.3 0.1 0.13 12.5 0.1 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DUF4362 PF14275.6 KIY66664.1 - 0.16 12.3 0.2 0.58 10.5 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4362) Integrase_H2C2 PF17921.1 KIY66666.1 - 2.1e-06 27.7 0.6 4.1e-06 26.8 0.6 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 KIY66668.1 - 0.0096 16.5 0.0 0.016 15.8 0.0 1.4 1 1 0 1 1 1 1 Aspartyl protease F-box-like PF12937.7 KIY66669.1 - 6.9e-06 25.9 1.0 6.9e-06 25.9 1.0 2.3 2 1 0 2 2 2 1 F-box-like F-box PF00646.33 KIY66669.1 - 8.5 6.4 13.5 2.1 8.3 0.1 4.1 4 0 0 4 4 4 0 F-box domain Glyco_transf_24 PF18404.1 KIY66670.1 - 2.6e-142 473.0 0.4 4.4e-142 472.2 0.4 1.4 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 KIY66670.1 - 6.7e-63 213.0 0.1 4.7e-61 207.0 0.0 2.7 3 1 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_12 PF18400.1 KIY66670.1 - 1.5e-49 168.4 0.0 2.4e-49 167.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 KIY66670.1 - 1.4e-38 131.3 0.0 2.5e-38 130.5 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Thioredoxin_13 PF18401.1 KIY66670.1 - 4.1e-38 130.4 0.2 2.8e-36 124.4 0.2 3.1 3 0 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_15 PF18403.1 KIY66670.1 - 1.2e-30 107.1 0.0 9.1e-29 100.9 0.0 3.0 3 0 0 3 3 3 1 Thioredoxin-like domain Glyco_transf_8 PF01501.20 KIY66670.1 - 3e-05 23.7 0.0 5.4e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Methyltransf_30 PF05430.11 KIY66675.1 - 0.18 11.7 0.0 0.34 10.8 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase Coatomer_WDAD PF04053.14 KIY66676.1 - 1.5e-134 449.4 0.0 2.2e-134 448.9 0.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.11 KIY66676.1 - 4.1e-110 368.3 0.0 6.3e-110 367.7 0.0 1.2 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 KIY66676.1 - 2e-45 151.8 10.0 4.3e-08 33.7 0.5 8.3 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY66676.1 - 6.3e-12 45.6 0.0 0.0071 16.6 0.0 6.0 4 1 3 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain TPR_14 PF13428.6 KIY66676.1 - 0.0092 16.7 5.2 11 7.1 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat Cytochrom_D1 PF02239.16 KIY66676.1 - 0.028 13.0 0.0 0.053 12.0 0.0 1.4 1 0 0 1 1 1 0 Cytochrome D1 heme domain Nup160 PF11715.8 KIY66676.1 - 0.036 12.7 3.8 1.8 7.1 0.0 3.6 2 1 2 4 4 4 0 Nucleoporin Nup120/160 Clathrin PF00637.20 KIY66676.1 - 0.13 12.1 0.0 0.32 10.9 0.0 1.7 1 0 0 1 1 1 0 Region in Clathrin and VPS TPR_2 PF07719.17 KIY66676.1 - 0.16 12.2 1.8 27 5.2 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1275 PF06912.11 KIY66678.1 - 7e-31 107.6 17.0 8.9e-31 107.3 17.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Zip PF02535.22 KIY66679.1 - 9.2 5.4 7.2 11 5.2 7.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter zf_UBZ PF18439.1 KIY66681.1 - 0.051 13.2 2.6 0.057 13.0 0.4 2.2 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-C2H2_2 PF12756.7 KIY66681.1 - 0.065 13.6 2.6 1.5 9.2 0.4 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-ACC PF17848.1 KIY66681.1 - 0.066 13.3 0.1 0.066 13.3 0.1 1.8 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain zf-C2HC5 PF06221.13 KIY66681.1 - 0.069 13.2 0.5 38 4.4 0.0 3.1 3 0 0 3 3 3 0 Putative zinc finger motif, C2HC5-type zf-Di19 PF05605.12 KIY66681.1 - 0.23 11.8 4.1 2.3 8.6 0.3 2.4 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Rad54_N PF08658.10 KIY66682.1 - 0.22 11.7 1.1 0.39 10.8 0.2 1.7 2 0 0 2 2 2 0 Rad54 N terminal zf-MYND PF01753.18 KIY66683.1 - 7.2e-06 26.0 16.4 2.3e-05 24.4 16.4 1.9 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 KIY66683.1 - 1.1 9.4 7.8 2.6 8.2 7.8 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 GMC_oxred_N PF00732.19 KIY66684.1 - 1.5e-50 172.2 0.0 2e-50 171.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIY66684.1 - 1.3e-28 100.3 0.0 2.6e-28 99.3 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_3 PF13738.6 KIY66684.1 - 0.00054 19.3 0.0 0.0066 15.7 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIY66684.1 - 0.0044 17.2 0.1 0.013 15.7 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KIY66684.1 - 0.0059 15.9 0.1 0.01 15.1 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 KIY66684.1 - 0.0074 15.4 0.1 0.017 14.2 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KIY66684.1 - 0.014 14.6 0.1 0.2 10.9 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIY66684.1 - 0.022 14.3 2.7 0.099 12.2 0.9 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KIY66684.1 - 0.047 12.7 0.2 0.077 12.0 0.2 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.14 KIY66684.1 - 0.048 12.4 0.2 0.13 10.9 0.1 1.7 2 0 0 2 2 2 0 HI0933-like protein Glyco_hydro_61 PF03443.14 KIY66686.1 - 1.2e-61 208.2 0.0 1.5e-61 208.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Aldedh PF00171.22 KIY66687.1 - 9.7e-105 350.7 0.1 1.2e-104 350.5 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Glyco_hydro_4C PF11975.8 KIY66687.1 - 0.12 12.4 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase C-terminal domain Pro_isomerase PF00160.21 KIY66688.1 - 7e-39 133.6 0.0 1.1e-38 133.0 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 KIY66688.1 - 1.3e-15 57.0 0.0 2.4e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1992 PF09350.10 KIY66689.1 - 2.3e-20 72.5 0.1 8.9e-20 70.6 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1992) Antimicrobial22 PF16047.5 KIY66689.1 - 8.4 6.4 6.7 1.6 8.6 0.4 2.2 2 0 0 2 2 2 0 Frog antimicrobial peptide Coiled-coil_56 PF09813.9 KIY66690.1 - 4.8e-06 26.5 0.0 6.6e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 FAA_hydrolase PF01557.18 KIY66691.1 - 1.5e-58 198.1 0.0 2e-58 197.7 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Mgm101p PF06420.12 KIY66692.1 - 7.1e-86 286.0 0.0 9.4e-86 285.6 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 DUF2868 PF11067.8 KIY66692.1 - 0.065 12.7 0.0 0.068 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) Rubella_Capsid PF05750.11 KIY66692.1 - 0.071 12.7 3.7 0.034 13.8 1.3 1.6 2 0 0 2 2 2 0 Rubella capsid protein Prothymosin PF03247.14 KIY66693.1 - 0.15 12.5 0.1 0.15 12.5 0.1 1.6 2 0 0 2 2 2 0 Prothymosin/parathymosin family EHN PF06441.12 KIY66694.1 - 2.2e-35 121.3 1.0 3.2e-34 117.6 0.0 2.2 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KIY66694.1 - 2.6e-14 53.5 0.0 4.1e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIY66694.1 - 6.2e-06 27.0 0.4 1.2e-05 26.1 0.4 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family RCR PF12273.8 KIY66695.1 - 0.39 11.4 6.3 0.14 12.9 2.1 2.4 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red EHN PF06441.12 KIY66696.1 - 7.5e-36 122.8 0.8 8.9e-35 119.3 0.0 2.3 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KIY66696.1 - 1.5e-12 47.7 0.1 2.6e-12 46.9 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIY66696.1 - 0.00085 20.0 5.9 0.00085 20.0 5.9 2.3 2 1 0 2 2 2 1 Alpha/beta hydrolase family GDPD PF03009.17 KIY66698.1 - 6.4e-30 104.7 0.0 1.5e-29 103.6 0.0 1.6 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 KIY66698.1 - 0.0061 17.0 0.1 0.021 15.3 0.1 1.9 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Acyltransferase PF01553.21 KIY66699.1 - 5.2e-27 94.1 0.0 8.6e-27 93.4 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase RDD PF06271.12 KIY66699.1 - 0.69 10.1 4.2 2.3 8.4 0.0 2.4 2 0 0 2 2 2 0 RDD family DUF4504 PF14953.6 KIY66701.1 - 5.4e-07 29.3 0.3 6.7e-05 22.4 0.3 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4504) SET PF00856.28 KIY66705.1 - 2.3e-08 34.6 0.1 3.8e-08 33.9 0.1 1.3 1 0 0 1 1 1 1 SET domain zf-MYND PF01753.18 KIY66705.1 - 1.2e-05 25.3 18.4 1.2e-05 25.3 18.4 1.8 2 0 0 2 2 2 1 MYND finger PolC_DP2 PF03833.13 KIY66705.1 - 1.2 6.9 3.1 1.5 6.6 3.1 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 SKN1 PF03935.15 KIY66706.1 - 7.8e-188 624.9 0.7 8.9e-188 624.7 0.7 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Abhydrolase_1 PF00561.20 KIY66707.1 - 2.9e-15 56.6 0.4 3.4e-14 53.1 0.4 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIY66707.1 - 3.2e-14 54.1 1.3 4.6e-14 53.5 1.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIY66707.1 - 7.2e-14 51.6 0.2 1.7e-13 50.4 0.2 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KIY66707.1 - 0.00057 19.4 0.5 0.077 12.5 0.1 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_4 PF08386.10 KIY66707.1 - 0.0015 18.6 0.0 0.0026 17.8 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein BAAT_C PF08840.11 KIY66707.1 - 0.0071 16.3 0.0 0.028 14.3 0.0 1.8 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_5 PF12695.7 KIY66707.1 - 0.029 14.1 0.0 4.3 7.1 0.0 2.4 2 0 0 2 2 2 0 Alpha/beta hydrolase family DLH PF01738.18 KIY66707.1 - 0.051 13.1 0.4 9 5.8 0.1 2.6 2 1 0 2 2 2 0 Dienelactone hydrolase family Nop14 PF04147.12 KIY66708.1 - 2.3e-284 946.0 14.1 3e-284 945.6 14.1 1.1 1 0 0 1 1 1 1 Nop14-like family Noc2 PF03715.13 KIY66708.1 - 0.0052 16.1 0.1 0.013 14.8 0.0 1.6 1 1 0 1 1 1 1 Noc2p family T6PP_N PF18572.1 KIY66708.1 - 0.064 13.1 3.0 0.055 13.3 0.4 2.3 2 0 0 2 2 2 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain Menin PF05053.13 KIY66708.1 - 0.12 10.7 8.1 0.32 9.3 8.1 1.6 1 0 0 1 1 1 0 Menin HRCT1 PF15758.5 KIY66708.1 - 0.18 12.8 0.3 0.49 11.4 0.3 1.7 1 0 0 1 1 1 0 Histidine-rich carboxyl terminus protein 1 Aldo_ket_red PF00248.21 KIY66709.1 - 6.6e-27 94.5 0.0 1.3e-26 93.5 0.0 1.4 1 1 0 1 1 1 1 Aldo/keto reductase family DER1 PF04511.15 KIY66710.1 - 4.4e-38 131.1 2.2 5.2e-38 130.9 2.2 1.1 1 0 0 1 1 1 1 Der1-like family GATA PF00320.27 KIY66714.1 - 6.3e-10 38.5 3.7 8.6e-10 38.1 3.7 1.2 1 0 0 1 1 1 1 GATA zinc finger ArfGap PF01412.18 KIY66714.1 - 0.017 15.2 0.1 0.018 15.1 0.1 1.1 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf Haem_bd PF14376.6 KIY66714.1 - 0.035 14.0 0.3 0.039 13.9 0.3 1.1 1 0 0 1 1 1 0 Haem-binding domain DZR PF12773.7 KIY66714.1 - 0.062 13.3 2.2 0.69 10.0 2.5 1.9 1 1 1 2 2 2 0 Double zinc ribbon eIF-3_zeta PF05091.12 KIY66718.1 - 2.8e-200 666.7 0.0 3.2e-200 666.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) NARG2_C PF10505.9 KIY66718.1 - 0.22 11.0 0.0 16 4.9 0.0 2.1 2 0 0 2 2 2 0 NMDA receptor-regulated gene protein 2 C-terminus RRM_1 PF00076.22 KIY66719.1 - 5.2e-16 58.2 0.0 1e-15 57.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KIY66719.1 - 0.00034 20.7 0.0 0.00074 19.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif RRM_5 PF13893.6 KIY66719.1 - 0.00058 19.5 0.0 0.00091 18.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TrkA_C PF02080.21 KIY66719.1 - 0.11 12.3 0.0 0.32 10.9 0.0 1.7 2 0 0 2 2 2 0 TrkA-C domain YL1 PF05764.13 KIY66719.1 - 0.19 11.8 25.6 0.3 11.2 25.6 1.3 1 0 0 1 1 1 0 YL1 nuclear protein RR_TM4-6 PF06459.12 KIY66719.1 - 3.3 7.5 11.3 4.5 7.0 11.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Hid1 PF12722.7 KIY66719.1 - 4.2 5.4 6.3 4.8 5.2 6.3 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein zf-MYND PF01753.18 KIY66720.1 - 3.3e-11 43.1 15.4 6.2e-11 42.2 15.4 1.5 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 KIY66720.1 - 0.081 13.0 3.3 0.14 12.3 3.3 1.4 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-C6H2 PF15801.5 KIY66720.1 - 1 9.7 14.8 0.22 11.8 11.3 1.7 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding zf-HIT PF04438.16 KIY66720.1 - 2.4 8.1 8.3 4.3 7.3 8.3 1.4 1 0 0 1 1 1 0 HIT zinc finger PAP_central PF04928.17 KIY66721.1 - 3.6e-109 363.5 0.0 4.6e-109 363.2 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 KIY66721.1 - 6.5e-55 185.4 0.0 1.2e-54 184.5 0.0 1.5 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 KIY66721.1 - 1.6e-10 41.1 0.0 3.6e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Nrap_D2 PF17403.2 KIY66721.1 - 0.0069 16.2 0.1 0.047 13.5 0.1 2.2 2 0 0 2 2 2 1 Nrap protein PAP/OAS-like domain Polbeta PF18765.1 KIY66721.1 - 0.079 13.1 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase Arf PF00025.21 KIY66722.1 - 1e-35 122.8 0.0 2.3e-35 121.6 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KIY66722.1 - 7.1e-11 41.9 0.0 3.3e-06 26.5 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 KIY66722.1 - 9.2e-09 35.6 0.0 1.5e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KIY66722.1 - 6.3e-07 29.1 0.0 8.8e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 KIY66722.1 - 1.9e-06 27.4 0.0 3.3e-06 26.7 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KIY66722.1 - 3e-05 24.1 0.0 4.9e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KIY66722.1 - 3.8e-05 23.2 0.0 4.7e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KIY66722.1 - 0.00016 21.3 0.0 0.075 12.6 0.0 2.1 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AAA_23 PF13476.6 KIY66722.1 - 0.00055 20.5 0.7 0.001 19.6 0.7 1.6 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 KIY66722.1 - 0.003 18.1 0.2 0.0067 16.9 0.1 1.6 2 0 0 2 2 2 1 ABC transporter cobW PF02492.19 KIY66722.1 - 0.0039 16.8 0.0 0.3 10.7 0.1 2.4 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 KIY66722.1 - 0.006 16.9 0.0 0.014 15.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KIY66722.1 - 0.0077 16.1 0.0 1.4 8.8 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_30 PF13604.6 KIY66722.1 - 0.013 15.2 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KIY66722.1 - 0.022 14.5 0.0 0.05 13.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 KIY66722.1 - 0.027 14.8 0.2 0.055 13.9 0.2 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 KIY66722.1 - 0.049 13.8 0.0 0.095 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KIY66722.1 - 0.05 14.1 0.1 0.1 13.2 0.1 1.8 1 1 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 KIY66722.1 - 0.058 13.1 0.0 0.093 12.4 0.0 1.3 1 0 0 1 1 1 0 Thymidylate kinase NACHT PF05729.12 KIY66722.1 - 0.12 12.3 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 NACHT domain Glyco_hydro_3_C PF01915.22 KIY66723.1 - 8.3e-44 150.0 0.0 1.7e-43 149.0 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KIY66723.1 - 1.3e-39 136.5 0.0 2e-39 135.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KIY66723.1 - 1.5e-20 73.1 0.0 3.6e-20 71.8 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain HEPN_SAV_6107 PF18726.1 KIY66724.1 - 0.25 11.9 2.3 1 9.9 0.1 2.6 2 1 1 3 3 3 0 SAV_6107-like HEPN PQ-loop PF04193.14 KIY66726.1 - 2.8e-19 68.6 3.2 1.5e-12 47.0 1.9 2.7 2 0 0 2 2 2 2 PQ loop repeat ER_lumen_recept PF00810.18 KIY66726.1 - 9.3e-05 23.3 2.8 0.00014 22.7 2.8 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor ADH_zinc_N PF00107.26 KIY66728.1 - 2.5e-19 69.6 0.0 4.7e-19 68.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KIY66728.1 - 2.9e-13 49.6 0.1 6.1e-13 48.6 0.1 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 KIY66728.1 - 0.0011 20.0 0.0 0.0023 19.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase EPF PF17181.4 KIY66729.1 - 0.0028 17.6 0.4 0.004 17.1 0.4 1.2 1 0 0 1 1 1 1 Epidermal patterning factor proteins XPB_DRD PF18458.1 KIY66729.1 - 0.06 13.2 0.0 0.088 12.7 0.0 1.3 1 0 0 1 1 1 0 Xeroderma pigmentosum group B helicase damage recognition domain RRM_1 PF00076.22 KIY66730.1 - 8.3e-23 80.0 0.3 5.9e-12 45.2 0.0 2.6 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KIY66730.1 - 4.1e-12 45.8 0.0 6.5e-07 29.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KIY66730.1 - 0.00029 20.6 0.1 0.0038 17.1 0.0 2.2 2 1 0 2 2 2 1 Occluded RNA-recognition motif Totivirus_coat PF05518.11 KIY66730.1 - 0.075 11.1 0.1 0.099 10.7 0.1 1.1 1 0 0 1 1 1 0 Totivirus coat protein PHM7_cyt PF14703.6 KIY66730.1 - 0.18 12.0 2.1 4.6 7.5 0.4 2.9 2 2 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Glyco_transf_8 PF01501.20 KIY66731.1 - 0.019 14.5 0.0 0.052 13.1 0.0 1.7 2 0 0 2 2 2 0 Glycosyl transferase family 8 Nucleotid_trans PF03407.16 KIY66731.1 - 0.11 12.5 0.2 0.96 9.4 0.5 2.0 2 0 0 2 2 2 0 Nucleotide-diphospho-sugar transferase TPR_2 PF07719.17 KIY66732.1 - 3.5e-16 57.9 1.5 3.2e-06 26.8 0.0 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 KIY66732.1 - 1e-14 53.6 0.1 6.4e-06 25.8 0.0 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 KIY66732.1 - 1.7e-14 53.2 5.6 2.1e-06 27.3 0.0 4.3 2 2 2 4 4 4 4 TPR repeat TPR_19 PF14559.6 KIY66732.1 - 1.3e-11 44.8 0.5 0.00016 22.1 0.4 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 KIY66732.1 - 4.1e-11 42.5 0.2 0.018 15.4 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 KIY66732.1 - 4.5e-11 43.2 0.1 0.00021 21.8 0.4 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 KIY66732.1 - 1.1e-10 41.7 1.4 0.0025 18.1 0.2 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KIY66732.1 - 1.2e-10 41.3 4.4 0.012 16.3 0.0 5.2 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 KIY66732.1 - 3.3e-08 33.1 0.5 0.064 13.5 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 KIY66732.1 - 3.7e-07 29.7 2.4 0.079 13.0 0.1 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 KIY66732.1 - 1.9e-05 25.0 0.1 0.41 11.4 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KIY66732.1 - 0.0002 21.5 0.1 0.55 10.5 0.0 2.2 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 KIY66732.1 - 0.00023 20.9 5.6 0.15 12.0 0.5 3.5 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_15 PF13429.6 KIY66732.1 - 0.00053 19.3 0.1 0.00078 18.7 0.1 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_9 PF13371.6 KIY66732.1 - 0.0014 18.7 0.1 0.38 10.9 0.2 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat MIT PF04212.18 KIY66732.1 - 0.0054 16.8 1.1 0.33 11.1 0.2 2.7 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain TPR_4 PF07721.14 KIY66732.1 - 0.025 15.1 4.6 2.3 9.1 0.1 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_20 PF14561.6 KIY66732.1 - 0.043 14.1 0.3 0.24 11.7 0.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC5 PF12862.7 KIY66732.1 - 0.054 13.6 0.1 0.22 11.6 0.0 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 LSM PF01423.22 KIY66733.1 - 3e-07 30.0 0.0 3.4e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 LSM domain PS_Dcarbxylase PF02666.15 KIY66734.1 - 5.2e-70 235.1 0.0 1.1e-68 230.7 0.0 2.0 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase Chitin_synth_2 PF03142.15 KIY66735.1 - 4e-235 781.4 0.1 6e-235 780.8 0.1 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 KIY66735.1 - 1.2e-135 453.4 0.0 8.4e-135 450.6 0.0 2.2 2 1 0 2 2 2 1 Myosin head (motor domain) DEK_C PF08766.11 KIY66735.1 - 3.3e-19 68.6 0.0 1.5e-18 66.5 0.0 2.2 2 0 0 2 2 2 1 DEK C terminal domain Cyt-b5 PF00173.28 KIY66735.1 - 1.2e-10 41.3 0.4 7.6e-06 26.0 0.1 3.0 2 1 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_tranf_2_3 PF13641.6 KIY66735.1 - 1.4e-09 38.2 0.1 1.5e-07 31.5 0.1 3.2 3 0 0 3 3 3 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 KIY66735.1 - 1.2e-08 35.1 4.2 1.2e-08 35.1 4.2 2.4 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 KIY66735.1 - 0.0015 18.4 0.0 1.7 8.4 0.0 2.7 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_hydro_3 PF00933.21 KIY66736.1 - 1.1e-78 264.9 0.0 1.5e-78 264.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Chitin_synth_1 PF01644.17 KIY66737.1 - 5.4e-78 260.6 0.1 8e-78 260.0 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KIY66737.1 - 6.9e-26 90.0 0.1 1.5e-25 88.9 0.1 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KIY66737.1 - 1e-24 87.1 4.4 1.5e-18 66.7 0.2 2.5 3 0 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KIY66737.1 - 2.8e-05 24.1 5.8 2.8e-05 24.1 5.8 2.6 1 1 1 2 2 2 1 Glycosyl transferase family group 2 GYR PF02756.14 KIY66737.1 - 0.05 13.3 2.7 0.11 12.2 2.7 1.6 1 0 0 1 1 1 0 GYR motif TPR_1 PF00515.28 KIY66738.1 - 7.5e-07 28.7 0.0 0.099 12.5 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KIY66738.1 - 0.00066 20.3 28.2 5.5 8.1 0.2 9.1 6 3 4 10 10 10 4 Tetratricopeptide repeat TPR_2 PF07719.17 KIY66738.1 - 0.011 15.7 18.8 1.4 9.2 0.0 8.0 9 1 0 9 9 9 0 Tetratricopeptide repeat MIT PF04212.18 KIY66738.1 - 0.15 12.2 0.9 0.98 9.5 0.0 2.8 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_8 PF13181.6 KIY66738.1 - 0.19 12.0 2.1 1.6e+02 2.9 0.0 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_17 PF13431.6 KIY66738.1 - 1.2 9.7 6.3 6.2 7.4 0.0 5.2 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_6 PF13174.6 KIY66738.1 - 1.2 9.9 10.8 13 6.7 1.2 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 KIY66738.1 - 3.1 8.4 15.5 15 6.2 0.3 6.0 7 0 0 7 7 7 0 Tetratricopeptide repeat EPF PF17181.4 KIY66740.1 - 0.0026 17.7 0.3 0.0035 17.3 0.3 1.3 1 0 0 1 1 1 1 Epidermal patterning factor proteins XPB_DRD PF18458.1 KIY66740.1 - 0.058 13.3 0.0 0.088 12.7 0.0 1.3 1 0 0 1 1 1 0 Xeroderma pigmentosum group B helicase damage recognition domain FliT PF05400.13 KIY66741.1 - 5.9 7.8 6.3 9.1 7.2 0.4 3.0 3 0 0 3 3 3 0 Flagellar protein FliT DHHC PF01529.20 KIY66742.1 - 6.4e-28 97.5 7.0 6.4e-28 97.5 7.0 1.7 2 0 0 2 2 2 1 DHHC palmitoyltransferase 7tm_7 PF08395.12 KIY66742.1 - 0.0037 16.5 7.2 0.0056 15.9 7.2 1.2 1 0 0 1 1 1 1 7tm Chemosensory receptor MIS13 PF08202.11 KIY66743.1 - 3.1e-10 39.8 0.5 6.7e-10 38.7 0.5 1.5 1 0 0 1 1 1 1 Mis12-Mtw1 protein family DEAD PF00270.29 KIY66744.1 - 8.6e-31 107.0 0.0 1.5e-30 106.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIY66744.1 - 1.3e-22 80.2 0.0 1.1e-21 77.3 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIY66744.1 - 6.8e-05 22.9 0.0 0.00011 22.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Ribosomal_L2_C PF03947.18 KIY66745.1 - 8.8e-50 168.1 1.4 1.9e-49 167.0 1.4 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 KIY66745.1 - 1.9e-22 79.0 0.3 4.2e-22 77.9 0.3 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain ADH_zinc_N PF00107.26 KIY66746.1 - 6.2e-12 45.6 0.0 1.1e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Porphobil_deam PF01379.20 KIY66747.1 - 6.3e-66 221.8 0.0 9.2e-66 221.2 0.0 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 KIY66747.1 - 6.5e-21 74.5 0.3 1.5e-20 73.3 0.3 1.6 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain CENP-T_C PF15511.6 KIY66748.1 - 4.9e-07 29.9 0.0 5.9e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 KIY66748.1 - 3.4e-05 23.9 0.1 4.8e-05 23.5 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 KIY66748.1 - 0.0002 21.6 0.0 0.00026 21.3 0.0 1.3 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KIY66748.1 - 0.00085 19.6 0.1 0.0016 18.7 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KIY66748.1 - 0.00094 19.5 0.2 0.0011 19.4 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KIY66748.1 - 0.058 13.5 0.0 0.067 13.3 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KIY66748.1 - 0.14 12.2 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated Ctr PF04145.15 KIY66749.1 - 5.1e-33 114.8 3.7 6.6e-33 114.4 3.7 1.1 1 0 0 1 1 1 1 Ctr copper transporter family ArsP_1 PF03773.13 KIY66749.1 - 0.00015 21.0 0.2 0.00018 20.8 0.2 1.1 1 0 0 1 1 1 1 Predicted permease CPBP PF02517.16 KIY66749.1 - 0.018 15.4 10.1 0.022 15.1 1.1 2.1 2 0 0 2 2 2 0 CPBP intramembrane metalloprotease DUF3561 PF12084.8 KIY66749.1 - 2.7 8.1 9.4 2 8.5 5.7 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF3561) Pkinase PF00069.25 KIY66750.1 - 1.3e-75 254.1 0.0 1.6e-75 253.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY66750.1 - 2e-36 125.6 0.0 2.9e-36 125.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY66750.1 - 2.1e-08 33.8 0.0 1.6e-07 30.9 0.0 1.9 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KIY66750.1 - 0.0012 17.8 0.0 0.002 17.0 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KIY66750.1 - 0.0015 17.6 0.3 0.0079 15.2 0.3 1.9 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KIY66750.1 - 0.0016 17.8 0.4 0.0041 16.5 0.4 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIY66750.1 - 0.11 12.5 0.1 1.4 8.7 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family TIP49 PF06068.13 KIY66752.1 - 2.4e-156 520.3 1.3 3.3e-156 519.9 1.3 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 KIY66752.1 - 5.7e-20 71.2 1.0 4.4e-19 68.4 0.9 2.4 2 0 0 2 2 2 1 TIP49 AAA-lid domain AAA PF00004.29 KIY66752.1 - 5.9e-09 36.4 0.3 1e-05 25.9 0.1 2.8 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KIY66752.1 - 1.7e-06 27.9 0.2 0.0039 16.9 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain DnaB_C PF03796.15 KIY66752.1 - 2.9e-05 23.6 0.6 5.4e-05 22.6 0.6 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.6 KIY66752.1 - 0.00075 19.9 0.1 0.0029 18.0 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 KIY66752.1 - 0.0028 17.1 2.6 0.046 13.1 0.3 2.6 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 KIY66752.1 - 0.006 16.9 1.1 0.063 13.6 1.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KIY66752.1 - 0.0063 16.5 0.4 6.3 6.8 0.0 3.2 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 KIY66752.1 - 0.0076 15.8 0.1 0.029 14.0 0.1 1.9 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KIY66752.1 - 0.0083 16.4 0.0 0.25 11.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain DNA_pol3_delta PF06144.13 KIY66752.1 - 0.14 12.0 0.0 0.37 10.6 0.0 1.7 2 0 0 2 2 2 0 DNA polymerase III, delta subunit eIF-1a PF01176.19 KIY66753.1 - 1.4e-23 82.4 0.1 2e-23 81.9 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 UbiA PF01040.18 KIY66754.1 - 6.4e-15 55.1 12.9 9e-15 54.7 12.9 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family Vps35 PF03635.17 KIY66755.1 - 8.5e-301 999.8 2.9 9.9e-301 999.6 2.9 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 MecA PF05389.12 KIY66755.1 - 0.0012 18.6 0.3 0.0032 17.1 0.3 1.7 1 0 0 1 1 1 1 Negative regulator of genetic competence (MecA) CLASP_N PF12348.8 KIY66755.1 - 0.093 12.3 0.1 24 4.4 0.0 3.3 3 0 0 3 3 3 0 CLASP N terminal RPN2_C PF18004.1 KIY66755.1 - 0.86 9.5 7.4 0.088 12.7 2.2 1.9 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain PTPRCAP PF15713.5 KIY66755.1 - 1.3 9.3 8.3 0.066 13.5 1.5 2.1 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated DUF4484 PF14831.6 KIY66755.1 - 1.8 8.5 5.6 0.37 10.8 0.4 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4484) GOLD_2 PF13897.6 KIY66755.1 - 1.9 9.0 5.2 2.3 8.7 0.5 2.4 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking U1snRNP70_N PF12220.8 KIY66755.1 - 8.2 7.2 9.5 16 6.2 0.2 3.1 3 0 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal TIP49 PF06068.13 KIY66756.1 - 7.9e-156 518.6 0.0 9.6e-156 518.4 0.0 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 KIY66756.1 - 4.3e-19 68.4 0.1 9.5e-19 67.3 0.1 1.6 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 KIY66756.1 - 1.1e-10 42.1 0.1 2.7e-06 27.9 0.1 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KIY66756.1 - 2.9e-08 33.6 0.0 1.9e-06 27.7 0.0 2.5 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KIY66756.1 - 9.1e-06 26.0 0.2 0.2 11.9 0.2 2.5 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KIY66756.1 - 1e-05 26.0 0.0 0.00016 22.1 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 KIY66756.1 - 3.8e-05 23.7 0.2 0.027 14.4 0.1 2.4 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 KIY66756.1 - 0.00055 19.6 2.8 0.00057 19.5 0.5 2.2 3 1 0 3 3 3 1 AAA domain AAA_28 PF13521.6 KIY66756.1 - 0.00099 19.4 0.2 0.0024 18.1 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.6 KIY66756.1 - 0.0052 17.1 1.5 0.14 12.5 1.5 2.6 1 1 0 1 1 1 1 AAA domain DnaB_C PF03796.15 KIY66756.1 - 0.014 14.8 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_lid_2 PF17863.1 KIY66756.1 - 0.021 14.6 0.1 0.053 13.4 0.1 1.6 1 0 0 1 1 1 0 AAA lid domain Zeta_toxin PF06414.12 KIY66756.1 - 0.04 13.2 0.1 0.078 12.2 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin Sigma54_activat PF00158.26 KIY66756.1 - 0.042 13.5 0.0 4 7.1 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain Mg_chelatase PF01078.21 KIY66756.1 - 0.064 12.6 0.1 0.41 10.0 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 KIY66756.1 - 0.067 13.7 0.1 0.19 12.3 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_7 PF12775.7 KIY66756.1 - 0.078 12.5 0.1 1.7 8.2 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region ResIII PF04851.15 KIY66756.1 - 0.078 13.0 0.0 1.6 8.7 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 KIY66756.1 - 0.08 12.7 0.1 0.16 11.7 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.6 KIY66756.1 - 0.089 13.0 0.1 0.78 9.9 0.0 2.5 4 0 0 4 4 4 0 AAA domain DUF2075 PF09848.9 KIY66756.1 - 0.12 11.6 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PseudoU_synth_1 PF01416.20 KIY66756.1 - 0.14 12.7 0.0 0.37 11.3 0.0 1.8 1 1 0 1 1 1 0 tRNA pseudouridine synthase DUF2013 PF09431.10 KIY66757.1 - 6.9e-53 178.5 1.3 6.9e-53 178.5 1.3 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2013) Rcd1 PF04078.13 KIY66757.1 - 0.12 11.6 0.3 0.74 9.1 0.1 2.0 2 0 0 2 2 2 0 Cell differentiation family, Rcd1-like PTCB-BRCT PF12738.7 KIY66758.1 - 4.4e-30 103.4 0.4 1.4e-11 44.2 0.0 3.7 3 0 0 3 3 3 3 twin BRCT domain BRCT PF00533.26 KIY66758.1 - 4.3e-28 97.5 0.0 3.9e-09 36.8 0.0 4.4 4 0 0 4 4 4 4 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KIY66758.1 - 1.9e-14 53.8 0.0 0.00021 21.6 0.0 4.5 4 0 0 4 4 4 4 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 KIY66758.1 - 3.5e-09 36.8 0.0 4e-05 23.8 0.0 3.4 3 0 0 3 3 3 2 DNA ligase 3 BRCT domain NIBRIN_BRCT_II PF16508.5 KIY66758.1 - 0.00022 21.5 0.0 0.00063 20.1 0.0 1.8 1 0 0 1 1 1 1 Second BRCT domain on Nijmegen syndrome breakage protein DUF3808 PF10300.9 KIY66759.1 - 7.3e-76 255.8 0.2 2.1e-75 254.3 0.1 1.8 2 1 0 2 2 2 1 Protein of unknown function (DUF3808) TPR_12 PF13424.6 KIY66759.1 - 3.2e-05 24.2 0.4 0.96 9.8 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KIY66759.1 - 3.3e-05 24.3 0.6 1.1 10.3 0.1 5.2 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 KIY66759.1 - 4.3e-05 23.3 2.6 0.13 12.4 0.5 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 KIY66759.1 - 0.00023 21.8 0.5 0.45 11.2 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KIY66759.1 - 0.0033 17.9 0.0 15 6.2 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 KIY66759.1 - 0.0039 17.7 0.4 4.1 8.2 0.1 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 KIY66759.1 - 0.0064 16.6 5.1 0.42 11.0 0.3 4.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_4 PF07721.14 KIY66759.1 - 0.012 16.1 0.0 16 6.4 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 KIY66759.1 - 0.38 10.6 1.6 25 4.9 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat F-box-like PF12937.7 KIY66760.1 - 1e-07 31.7 0.1 2.6e-07 30.4 0.1 1.8 1 0 0 1 1 1 1 F-box-like Med13_C PF06333.12 KIY66761.1 - 2.8e-48 164.9 0.0 2.8e-48 164.9 0.0 3.1 3 1 0 3 3 3 1 Mediator complex subunit 13 C-terminal domain Med13_N PF11597.8 KIY66761.1 - 1.7e-26 93.4 0.4 1.7e-26 93.4 0.4 1.7 2 0 0 2 2 2 1 Mediator complex subunit 13 N-terminal MID_MedPIWI PF18296.1 KIY66761.1 - 0.043 13.6 0.0 0.22 11.3 0.0 2.1 1 1 0 2 2 2 0 MID domain of medPIWI MerR PF00376.23 KIY66761.1 - 0.082 12.7 0.0 0.28 11.0 0.0 1.9 1 0 0 1 1 1 0 MerR family regulatory protein Astro_capsid_p PF12226.8 KIY66761.1 - 0.4 9.8 2.4 0.69 9.0 2.4 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein p450 PF00067.22 KIY66762.1 - 9e-72 242.3 0.0 1.4e-70 238.4 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 zf-MYND PF01753.18 KIY66763.1 - 1.9e-09 37.4 2.4 1.9e-09 37.4 2.4 2.0 2 0 0 2 2 2 1 MYND finger F-box-like PF12937.7 KIY66764.1 - 4.6e-08 32.8 3.4 1.7e-07 31.0 3.4 2.1 1 1 0 1 1 1 1 F-box-like eIF3_N PF09440.10 KIY66765.1 - 2.3e-46 157.5 1.6 2.3e-46 157.5 1.6 2.3 3 0 0 3 3 3 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 KIY66765.1 - 9.3e-09 35.7 0.1 3e-08 34.1 0.1 1.9 1 0 0 1 1 1 1 PCI domain R3H PF01424.22 KIY66766.1 - 3.2e-09 36.7 0.3 5.5e-09 35.9 0.3 1.4 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.17 KIY66766.1 - 3.7e-07 30.1 51.2 6.8e-05 22.8 12.7 13.6 15 1 0 15 15 15 7 NF-X1 type zinc finger F-box-like PF12937.7 KIY66767.1 - 7.8e-06 25.7 2.7 2.2e-05 24.2 2.7 1.9 1 1 0 1 1 1 1 F-box-like DUF2433 PF10360.9 KIY66768.1 - 5.7e-44 149.2 0.4 5.7e-44 149.2 0.4 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2433) RRM_1 PF00076.22 KIY66768.1 - 9e-07 28.6 0.0 1.8e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4358 PF14270.6 KIY66768.1 - 0.14 12.5 0.1 0.3 11.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4358) Metallophos PF00149.28 KIY66768.1 - 0.15 12.5 0.0 0.28 11.7 0.0 1.5 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase Sortilin-Vps10 PF15902.5 KIY66769.1 - 3.5e-282 935.8 6.9 4.5e-149 497.1 0.9 2.2 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 KIY66769.1 - 1.5e-93 311.8 16.6 1e-49 169.1 3.6 2.5 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 KIY66769.1 - 2.6e-09 35.7 40.8 3.7 7.9 0.1 12.4 11 0 0 11 11 11 4 BNR/Asp-box repeat BNR_2 PF13088.6 KIY66769.1 - 9.2e-05 21.9 2.5 4.9 6.4 0.0 5.5 5 1 0 5 5 5 3 BNR repeat-like domain PSII_BNR PF14870.6 KIY66769.1 - 0.00092 18.6 5.4 2.3 7.4 0.0 5.2 5 1 1 6 6 6 3 Photosynthesis system II assembly factor YCF48 CHB_HEX_C PF03174.13 KIY66769.1 - 0.0099 15.8 3.2 11 6.1 0.1 4.9 6 1 1 7 7 7 2 Chitobiase/beta-hexosaminidase C-terminal domain Fe_dep_repr_C PF02742.15 KIY66769.1 - 0.024 14.7 0.1 0.29 11.2 0.0 2.6 3 0 0 3 3 3 0 Iron dependent repressor, metal binding and dimerisation domain Pro_CA PF00484.19 KIY66770.1 - 1.6e-19 70.7 0.0 2e-19 70.4 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase F-box-like PF12937.7 KIY66771.1 - 0.00054 19.8 0.0 0.0015 18.4 0.0 1.8 1 1 0 1 1 1 1 F-box-like Glyco_hydro_115 PF15979.5 KIY66773.1 - 2.9e-141 470.8 0.3 4.1e-141 470.3 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 115 GH115_C PF17829.1 KIY66773.1 - 8e-50 169.0 0.0 1.5e-49 168.2 0.0 1.5 1 0 0 1 1 1 1 Gylcosyl hydrolase family 115 C-terminal domain GPI-anchored PF10342.9 KIY66774.1 - 2.9e-07 31.2 2.9 2.9e-07 31.2 2.9 2.1 1 1 1 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DLH PF01738.18 KIY66778.1 - 3.7e-18 65.9 0.0 4.3e-18 65.7 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Ehrlichia_rpt PF09528.10 KIY66779.1 - 0.19 11.2 0.1 0.33 10.5 0.1 1.3 1 0 0 1 1 1 0 Ehrlichia tandem repeat (Ehrlichia_rpt) Lustrin_cystein PF14625.6 KIY66779.1 - 2.6 8.5 6.4 1.1 9.7 0.7 2.2 2 0 0 2 2 2 0 Lustrin, cysteine-rich repeated domain Amidohydro_2 PF04909.14 KIY66781.1 - 2e-18 67.2 0.1 2.7e-18 66.8 0.1 1.2 1 0 0 1 1 1 1 Amidohydrolase DUF4449 PF14613.6 KIY66782.1 - 4.4e-34 118.0 0.5 4.4e-34 118.0 0.5 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) MLTR_LBD PF17765.1 KIY66782.1 - 0.3 11.2 2.0 1.2 9.2 0.1 2.7 3 1 0 3 3 3 0 MmyB-like transcription regulator ligand binding domain FUSC PF04632.12 KIY66782.1 - 5.2 5.5 4.3 30 2.9 1.3 2.3 2 0 0 2 2 2 0 Fusaric acid resistance protein family LapA_dom PF06305.11 KIY66783.1 - 6.2 6.7 6.5 19 5.2 0.0 2.9 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain F-box-like PF12937.7 KIY66784.1 - 7.6e-06 25.7 0.1 1.6e-05 24.7 0.1 1.5 1 0 0 1 1 1 1 F-box-like SNF2_N PF00176.23 KIY66785.1 - 1.4e-56 191.8 0.0 1.5e-48 165.3 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 KIY66785.1 - 3.3e-15 56.4 0.0 1.7e-14 54.1 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIY66785.1 - 1e-06 28.9 0.0 2e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 KIY66785.1 - 1.3e-05 24.9 3.3 1.3e-05 24.9 3.3 2.4 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.29 KIY66785.1 - 5e-05 23.1 0.0 0.00013 21.8 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_2 PF13639.6 KIY66785.1 - 0.00013 22.3 5.1 0.00013 22.3 5.1 2.6 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KIY66785.1 - 0.00014 21.6 3.5 0.00014 21.6 3.5 2.6 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KIY66785.1 - 0.00062 20.0 1.8 0.00062 20.0 1.8 1.9 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 KIY66785.1 - 0.0011 18.8 3.4 0.0011 18.8 3.4 2.2 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 KIY66785.1 - 0.0013 18.5 1.8 0.0035 17.1 1.8 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 KIY66785.1 - 0.0069 16.2 3.6 0.0069 16.2 3.6 2.1 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KIY66785.1 - 0.015 15.4 2.8 0.015 15.4 2.8 2.0 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 KIY66785.1 - 0.017 15.1 0.1 0.017 15.1 0.1 2.9 2 2 1 3 3 2 0 RING-type zinc-finger zf-ANAPC11 PF12861.7 KIY66785.1 - 0.026 14.6 0.7 0.07 13.2 0.7 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Roughex PF06020.11 KIY66786.1 - 0.071 12.2 2.2 0.077 12.1 2.2 1.1 1 0 0 1 1 1 0 Drosophila roughex protein Nucleo_P87 PF07267.11 KIY66786.1 - 0.27 10.1 1.1 0.26 10.1 1.1 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 VWA PF00092.28 KIY66787.1 - 0.0012 19.2 0.0 0.0087 16.3 0.0 2.2 1 1 1 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.6 KIY66787.1 - 0.016 15.9 0.0 0.043 14.5 0.0 1.9 1 1 0 1 1 1 0 von Willebrand factor type A domain Copine PF07002.16 KIY66787.1 - 0.025 14.1 0.0 0.043 13.3 0.0 1.4 1 0 0 1 1 1 0 Copine Ribosomal_S4 PF00163.19 KIY66788.1 - 2.3e-12 47.7 0.9 3.2e-12 47.2 0.9 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.25 KIY66788.1 - 1.9e-11 43.5 0.0 3.1e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 S4 domain LIM_bind PF01803.16 KIY66789.1 - 6.3e-53 179.8 0.0 6.3e-53 179.8 0.0 3.2 3 0 0 3 3 3 1 LIM-domain binding protein DUF4407 PF14362.6 KIY66789.1 - 0.077 12.3 2.3 0.11 11.8 2.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SpoIIP PF07454.11 KIY66789.1 - 0.08 12.4 7.5 0.14 11.6 7.5 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF913 PF06025.12 KIY66789.1 - 0.17 10.8 0.8 0.3 10.0 0.8 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) CPSF100_C PF13299.6 KIY66789.1 - 0.38 10.9 4.4 0.88 9.7 4.4 1.5 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal RR_TM4-6 PF06459.12 KIY66789.1 - 0.74 9.6 6.2 1.6 8.5 6.2 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PIP5K PF01504.18 KIY66789.1 - 1 8.5 4.2 1.8 7.7 4.2 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase G0-G1_switch_2 PF15103.6 KIY66789.1 - 1.5 9.2 5.1 3.8 8.0 5.1 1.6 1 0 0 1 1 1 0 G0/G1 switch protein 2 Band_3_cyto PF07565.13 KIY66789.1 - 2.2 8.0 6.1 4.7 6.9 6.1 1.4 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Neur_chan_memb PF02932.16 KIY66789.1 - 5.5 7.0 8.8 0.18 11.8 0.9 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region EPL1 PF10513.9 KIY66789.1 - 9.9 6.5 13.5 0.76 10.1 8.1 1.8 2 0 0 2 2 2 0 Enhancer of polycomb-like p450 PF00067.22 KIY66792.1 - 1.7e-53 182.0 0.3 8.9e-53 179.7 0.3 2.0 1 1 0 1 1 1 1 Cytochrome P450 FmdA_AmdA PF03069.15 KIY66793.1 - 1.1e-160 534.6 0.0 1.3e-160 534.4 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family zf-MYND PF01753.18 KIY66794.1 - 1.9e-07 31.0 14.8 1.9e-07 31.0 14.8 2.1 2 0 0 2 2 2 1 MYND finger Rhodanese_C PF12368.8 KIY66794.1 - 0.31 11.4 6.6 0.71 10.3 6.6 1.5 1 0 0 1 1 1 0 Rhodanase C-terminal DUF2721 PF11026.8 KIY66795.1 - 0.011 15.7 3.8 0.043 13.7 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) Insulin_TMD PF17870.1 KIY66795.1 - 0.17 12.0 0.5 0.17 12.0 0.5 2.4 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment DUF2207 PF09972.9 KIY66795.1 - 0.52 9.0 4.5 3.1 6.4 4.7 1.8 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Abhydrolase_1 PF00561.20 KIY66796.1 - 1.1e-15 58.0 0.1 6.4e-15 55.5 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIY66796.1 - 6.7e-15 56.3 0.2 9.9e-15 55.7 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 KIY66796.1 - 8.7e-09 35.8 0.0 1.1e-08 35.5 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Hydrolase_4 PF12146.8 KIY66796.1 - 3.2e-08 33.1 0.0 4.1e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 KIY66796.1 - 3.7e-07 30.1 0.1 0.00012 21.9 0.2 2.2 1 1 1 2 2 2 2 PGAP1-like protein DUF676 PF05057.14 KIY66796.1 - 3.6e-05 23.4 0.0 6.2e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Chlorophyllase2 PF12740.7 KIY66796.1 - 0.0045 15.9 0.0 0.0065 15.4 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 KIY66796.1 - 0.034 13.1 0.1 0.055 12.5 0.1 1.3 1 0 0 1 1 1 0 Chlorophyllase DUF2048 PF09752.9 KIY66796.1 - 0.18 10.9 0.0 0.54 9.3 0.0 1.8 1 1 0 1 1 1 0 Abhydrolase domain containing 18 Esterase PF00756.20 KIY66796.1 - 0.19 11.4 0.1 0.39 10.3 0.1 1.4 1 0 0 1 1 1 0 Putative esterase p450 PF00067.22 KIY66797.1 - 1.8e-69 234.7 0.1 4.8e-69 233.3 0.1 1.6 1 1 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.18 KIY66799.1 - 1.8e-11 43.6 0.1 3e-11 42.9 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY66799.1 - 6.9e-08 32.5 8.0 6.9e-08 32.5 8.0 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-H2C2_2 PF13465.6 KIY66799.1 - 4.4e-05 23.7 2.8 4.4e-05 23.7 2.8 3.8 3 1 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.26 KIY66799.1 - 0.0053 17.1 0.6 0.0053 17.1 0.6 3.9 5 0 0 5 5 5 2 Zinc finger, C2H2 type zf-met PF12874.7 KIY66799.1 - 0.011 16.2 3.4 0.22 12.0 0.5 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type PSI_integrin PF17205.3 KIY66799.1 - 0.027 14.2 1.2 0.027 14.2 1.2 2.7 2 1 1 3 3 3 0 Integrin plexin domain zf-C2H2_6 PF13912.6 KIY66799.1 - 0.055 13.5 0.3 0.055 13.5 0.3 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_4 PF13894.6 KIY66799.1 - 0.065 14.1 1.5 0.065 14.1 1.5 4.8 5 0 0 5 5 5 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KIY66799.1 - 0.92 9.9 8.0 6.2 7.2 0.1 3.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding DHO_dh PF01180.21 KIY66800.1 - 1.2e-15 57.5 0.0 4e-15 55.8 0.0 1.7 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase HMG_box PF00505.19 KIY66801.1 - 1.2e-11 44.8 0.0 1.5e-11 44.5 0.0 1.1 1 0 0 1 1 1 1 HMG (high mobility group) box SprT-like PF10263.9 KIY66802.1 - 1e-27 96.2 0.3 1.8e-27 95.4 0.3 1.4 1 0 0 1 1 1 1 SprT-like family Zn_ribbon_SprT PF17283.2 KIY66802.1 - 3.4e-05 23.7 3.1 9.1e-05 22.3 3.1 1.8 1 0 0 1 1 1 1 SprT-like zinc ribbon domain DUF4379 PF14311.6 KIY66802.1 - 0.8 10.1 5.4 1.6 9.1 4.6 2.0 1 1 0 1 1 1 0 Probable Zinc-ribbon domain zf-H2C2_2 PF13465.6 KIY66804.1 - 7.6e-06 26.1 2.7 0.00097 19.5 0.3 3.3 3 1 0 3 3 3 2 Zinc-finger double domain zf-H2C2_5 PF13909.6 KIY66804.1 - 4.8e-05 23.0 11.1 0.0015 18.2 0.1 3.2 3 1 0 3 3 3 2 C2H2-type zinc-finger domain OrsD PF12013.8 KIY66804.1 - 0.00031 21.2 4.2 0.12 12.8 0.6 2.2 2 0 0 2 2 2 2 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2 PF00096.26 KIY66804.1 - 0.012 16.0 13.7 0.064 13.7 0.1 2.8 3 0 0 3 3 3 0 Zinc finger, C2H2 type FOXP-CC PF16159.5 KIY66804.1 - 0.019 15.6 0.7 3 8.5 0.0 2.1 1 1 1 2 2 2 0 FOXP coiled-coil domain Pacifastin_I PF05375.13 KIY66804.1 - 0.043 13.5 0.3 5.1 6.9 0.0 2.3 2 0 0 2 2 2 0 Pacifastin inhibitor (LCMII) zf-C2H2_4 PF13894.6 KIY66804.1 - 0.27 12.2 10.5 0.88 10.6 0.1 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger MFAP1 PF06991.11 KIY66805.1 - 1.4e-64 217.9 28.1 1.4e-64 217.9 28.1 3.1 1 1 0 2 2 2 1 Microfibril-associated/Pre-mRNA processing NAD_binding_8 PF13450.6 KIY66805.1 - 9.7e-15 54.6 0.0 2.3e-14 53.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KIY66805.1 - 0.00017 21.3 2.5 0.0088 15.7 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KIY66805.1 - 0.0063 16.5 0.0 0.017 15.1 0.0 1.7 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 KIY66805.1 - 0.023 13.9 0.0 0.054 12.7 0.0 1.6 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 KIY66805.1 - 0.058 12.6 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Thi4 family DJ-1_PfpI PF01965.24 KIY66806.1 - 4.7e-17 62.3 0.0 6.8e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family DUF411 PF04214.13 KIY66807.1 - 0.11 12.4 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF NmrA PF05368.13 KIY66810.1 - 6.6e-29 101.1 0.0 8e-29 100.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KIY66810.1 - 3.1e-12 46.8 0.0 1.2e-11 44.8 0.0 1.9 1 1 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KIY66810.1 - 1.4e-07 31.8 0.2 2.4e-07 31.1 0.2 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 KIY66810.1 - 0.00085 19.3 0.1 0.0014 18.6 0.1 1.3 1 0 0 1 1 1 1 KR domain TrkA_N PF02254.18 KIY66810.1 - 0.0057 16.9 0.3 0.018 15.3 0.1 1.8 2 0 0 2 2 2 1 TrkA-N domain Epimerase PF01370.21 KIY66810.1 - 0.021 14.3 0.0 0.03 13.8 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 KIY66810.1 - 0.085 13.3 0.1 0.14 12.6 0.1 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 KIY66810.1 - 0.12 12.5 0.1 0.21 11.7 0.1 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus UMP1 PF05348.11 KIY66811.1 - 1.4e-36 125.2 0.1 1.8e-36 124.9 0.1 1.0 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 SPRY PF00622.28 KIY66812.1 - 9.4e-23 80.6 0.0 1.4e-22 80.0 0.0 1.3 1 0 0 1 1 1 1 SPRY domain CLTH PF10607.9 KIY66812.1 - 4e-20 72.2 0.0 5.4e-20 71.8 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 KIY66812.1 - 3.4e-06 26.8 0.3 1.2e-05 25.0 0.0 2.1 2 0 0 2 2 2 1 LisH LisH_TPL PF17814.1 KIY66812.1 - 0.18 11.5 0.0 0.41 10.4 0.0 1.5 1 0 0 1 1 1 0 LisH-like dimerisation domain FtsQ PF03799.15 KIY66813.1 - 0.072 13.9 0.0 0.34 11.7 0.0 2.1 1 1 0 1 1 1 0 Cell division protein FtsQ Tim17 PF02466.19 KIY66819.1 - 0.039 14.3 6.0 0.4 11.1 0.1 3.7 4 0 0 4 4 4 0 Tim17/Tim22/Tim23/Pmp24 family TMEM135_C_rich PF15982.5 KIY66819.1 - 0.091 13.4 0.9 0.85 10.2 0.3 2.8 2 1 0 2 2 2 0 N-terminal cysteine-rich region of Transmembrane protein 135 Aminotran_5 PF00266.19 KIY66820.1 - 2.5e-39 135.3 0.0 3.1e-39 135.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KIY66820.1 - 0.006 15.8 0.0 0.0097 15.1 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II PikAIV_N PF18605.1 KIY66824.1 - 0.02 14.4 0.6 0.037 13.6 0.6 1.5 1 0 0 1 1 1 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain DUF2312 PF10073.9 KIY66824.1 - 0.03 14.0 0.1 0.053 13.2 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2312) bZIP_2 PF07716.15 KIY66824.1 - 0.037 14.1 3.1 0.073 13.2 3.1 1.5 1 0 0 1 1 1 0 Basic region leucine zipper DivIC PF04977.15 KIY66824.1 - 0.041 13.7 0.2 0.065 13.0 0.2 1.3 1 0 0 1 1 1 0 Septum formation initiator Shugoshin_N PF07558.11 KIY66824.1 - 0.11 12.3 0.6 0.22 11.4 0.6 1.5 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region TSC22 PF01166.18 KIY66824.1 - 0.19 12.1 1.2 0.31 11.4 1.2 1.3 1 0 0 1 1 1 0 TSC-22/dip/bun family DUF5067 PF16729.5 KIY66825.1 - 0.041 13.8 0.0 0.1 12.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5067) F-box-like PF12937.7 KIY66827.1 - 1.8e-07 30.9 2.4 1.1e-06 28.4 1.5 2.5 2 1 0 2 2 2 1 F-box-like Glyco_hydro_88 PF07470.13 KIY66828.1 - 9.7e-14 51.2 0.1 1.4e-13 50.7 0.1 1.1 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 DEAD PF00270.29 KIY66829.1 - 6.4e-46 156.3 0.0 4.5e-45 153.6 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIY66829.1 - 1.8e-33 115.2 0.0 1.9e-29 102.2 0.0 3.1 2 1 1 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 KIY66829.1 - 1.6e-06 28.2 0.0 4.6e-06 26.7 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KIY66829.1 - 0.023 13.9 1.3 0.025 13.8 0.0 1.7 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase UTP25 PF06862.12 KIY66829.1 - 0.028 13.2 0.0 0.064 12.0 0.0 1.5 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 CMS1 PF14617.6 KIY66829.1 - 0.13 11.5 0.0 0.13 11.5 0.0 3.0 2 2 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit CCDC53 PF10152.9 KIY66829.1 - 0.83 10.1 7.0 1.6 9.1 7.0 1.5 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex FAM60A PF15396.6 KIY66829.1 - 5.4 7.0 7.3 8.4 6.3 7.3 1.3 1 0 0 1 1 1 0 Protein Family FAM60A XRCC4 PF06632.12 KIY66829.1 - 5.7 5.7 12.7 8.5 5.1 12.7 1.2 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 PRA1 PF03208.19 KIY66830.1 - 1.5 8.5 7.6 59 3.3 7.3 2.7 3 0 0 3 3 3 0 PRA1 family protein DUF805 PF05656.14 KIY66830.1 - 4.1 7.9 6.4 11 6.5 6.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF805) E1-E2_ATPase PF00122.20 KIY66830.1 - 7 6.1 10.0 28 4.2 0.0 2.3 1 1 2 3 3 3 0 E1-E2 ATPase Spore_YtrH PF14034.6 KIY66831.1 - 0.044 13.9 3.7 0.19 11.9 1.5 2.3 2 0 0 2 2 2 0 Sporulation protein YtrH DUF805 PF05656.14 KIY66831.1 - 5.3 7.5 5.7 13 6.3 5.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF805) Glyphos_transf PF04464.14 KIY66832.1 - 0.16 10.9 0.0 0.2 10.6 0.0 1.1 1 0 0 1 1 1 0 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase Peroxidase_2 PF01328.17 KIY66833.1 - 2.1e-51 175.1 0.0 2.5e-51 174.9 0.0 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 WD40 PF00400.32 KIY66834.1 - 0.042 14.7 0.2 48 5.1 0.0 4.1 5 0 0 5 5 5 0 WD domain, G-beta repeat DPPIV_N PF00930.21 KIY66834.1 - 0.09 11.5 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF3261 PF11659.8 KIY66834.1 - 0.11 12.3 0.0 0.31 10.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3261) Glyco_trans_2_3 PF13632.6 KIY66835.1 - 0.0062 16.5 0.1 0.01 15.7 0.1 1.3 1 1 0 1 1 1 1 Glycosyl transferase family group 2 FtsX PF02687.21 KIY66835.1 - 1.6 9.2 12.1 55 4.3 7.3 3.1 2 1 0 2 2 2 0 FtsX-like permease family LRRNT PF01462.18 KIY66837.1 - 0.00083 18.9 1.1 0.0013 18.4 0.4 1.7 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain Forkhead PF00250.18 KIY66838.1 - 1.2e-07 31.9 0.0 2e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Forkhead domain DNA_pol_B PF00136.21 KIY66839.1 - 2.2e-114 382.7 0.0 3e-114 382.3 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.10 KIY66839.1 - 2.8e-52 177.2 0.8 5.8e-52 176.1 0.8 1.6 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 KIY66839.1 - 4.1e-26 91.9 0.2 1.7e-25 89.9 0.2 2.0 1 1 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.8 KIY66839.1 - 1.4e-20 73.2 7.8 4.6e-20 71.5 7.8 2.0 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal KR PF08659.10 KIY66839.1 - 0.039 13.9 0.0 0.078 12.9 0.0 1.4 1 0 0 1 1 1 0 KR domain DNA_pol_B_2 PF03175.13 KIY66839.1 - 0.04 12.8 0.0 0.09 11.6 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral Voltage_CLC PF00654.20 KIY66841.1 - 1.8e-84 284.0 30.1 1.8e-84 284.0 30.1 1.9 1 1 1 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 KIY66841.1 - 4.4e-06 27.1 0.0 0.012 16.0 0.0 2.6 2 0 0 2 2 2 2 CBS domain Med4 PF10018.9 KIY66842.1 - 5.3e-22 78.4 0.0 7.8e-22 77.9 0.0 1.2 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 CortBP2 PF09727.9 KIY66842.1 - 0.036 14.0 1.0 0.052 13.5 1.0 1.2 1 0 0 1 1 1 0 Cortactin-binding protein-2 ABC_tran_CTD PF16326.5 KIY66842.1 - 0.64 10.3 6.0 14 6.0 3.0 2.4 2 0 0 2 2 2 0 ABC transporter C-terminal domain IBR PF01485.21 KIY66843.1 - 7.3e-06 26.1 17.2 0.0055 16.9 7.4 3.1 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain zinc_ribbon_9 PF14369.6 KIY66843.1 - 0.0035 17.5 7.1 0.43 10.9 0.4 4.3 4 0 0 4 4 4 1 zinc-ribbon ADD_ATRX PF17981.1 KIY66843.1 - 0.016 15.1 3.9 0.016 15.1 3.9 2.2 2 0 0 2 2 2 0 Cysteine Rich ADD domain Zn-ribbon_8 PF09723.10 KIY66843.1 - 0.03 14.4 6.7 9.2 6.5 0.4 3.8 3 0 0 3 3 3 0 Zinc ribbon domain zf-TFIIB PF13453.6 KIY66843.1 - 0.036 13.4 8.2 1.2 8.5 0.0 3.6 3 0 0 3 3 3 0 Transcription factor zinc-finger zf-ACC PF17848.1 KIY66843.1 - 0.15 12.1 1.0 0.15 12.1 1.0 3.7 3 0 0 3 3 3 0 Acetyl-coA carboxylase zinc finger domain zf-UDP PF14569.6 KIY66843.1 - 0.3 11.2 13.1 0.05 13.7 3.1 3.3 2 2 1 3 3 3 0 Zinc-binding RING-finger DSPc PF00782.20 KIY66844.1 - 8.2e-26 90.4 0.0 9.6e-26 90.2 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KIY66844.1 - 0.00023 20.8 0.0 0.00029 20.5 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 KIY66844.1 - 0.00094 19.5 0.0 0.0014 18.9 0.0 1.3 1 0 0 1 1 1 1 Rit1 DUSP-like domain Myotub-related PF06602.14 KIY66844.1 - 0.095 11.6 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain Melibiase_2 PF16499.5 KIY66845.1 - 3e-18 66.0 2.4 7.3e-11 41.8 0.8 2.1 1 1 1 2 2 2 2 Alpha galactosidase A Melibiase_C PF17801.1 KIY66845.1 - 5.4e-08 32.8 0.0 9.3e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain Glyco_hydro_97 PF10566.9 KIY66845.1 - 0.00054 19.3 0.0 0.0022 17.4 0.0 1.8 1 1 0 1 1 1 1 Glycoside hydrolase 97 Thaumatin PF00314.17 KIY66846.1 - 1.8e-28 99.6 1.6 2e-28 99.5 1.6 1.0 1 0 0 1 1 1 1 Thaumatin family Glyco_hydro_64 PF16483.5 KIY66846.1 - 0.13 11.6 0.0 0.13 11.5 0.0 1.0 1 0 0 1 1 1 0 Beta-1,3-glucanase F-box-like PF12937.7 KIY66848.1 - 4.2e-05 23.3 0.5 0.00011 22.0 0.5 1.7 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KIY66848.1 - 0.0028 18.0 1.1 0.2 12.1 0.2 3.4 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) Zip PF02535.22 KIY66849.1 - 1.2e-58 199.0 18.0 1.5e-58 198.6 18.0 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Cation_ATPase_C PF00689.21 KIY66849.1 - 1.6 8.4 8.9 0.38 10.4 0.4 2.7 2 1 1 3 3 3 0 Cation transporting ATPase, C-terminus PTR2 PF00854.21 KIY66850.1 - 6.7e-79 265.6 7.5 9.3e-79 265.1 7.5 1.2 1 0 0 1 1 1 1 POT family Thaumatin PF00314.17 KIY66851.1 - 5.7e-71 238.6 13.5 6.5e-71 238.4 13.5 1.0 1 0 0 1 1 1 1 Thaumatin family Glyco_hydro_64 PF16483.5 KIY66851.1 - 1.7e-05 24.3 0.2 3.7e-05 23.2 0.0 1.5 1 1 1 2 2 2 1 Beta-1,3-glucanase LRR_4 PF12799.7 KIY66852.1 - 0.19 12.2 0.8 19 5.9 0.0 3.1 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KIY66853.1 - 5.7e-07 29.3 1.4 1.8e-06 27.7 1.4 1.8 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KIY66853.1 - 0.036 14.0 0.0 3.1 7.8 0.0 2.4 2 0 0 2 2 2 0 F-box domain RNase_P_Rpp14 PF01900.19 KIY66854.1 - 5.3e-27 94.1 0.0 6.7e-27 93.7 0.0 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family ABC_tran_Xtn PF12848.7 KIY66854.1 - 0.098 12.7 1.0 6.8 6.8 0.1 2.2 1 1 1 2 2 2 0 ABC transporter Thaumatin PF00314.17 KIY66855.1 - 3.4e-10 39.9 1.7 3.8e-10 39.8 1.7 1.0 1 0 0 1 1 1 1 Thaumatin family PQQ PF01011.21 KIY66855.1 - 0.081 12.9 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 PQQ enzyme repeat F-box-like PF12937.7 KIY66856.1 - 8.6e-06 25.5 0.4 3.3e-05 23.7 0.4 2.0 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KIY66857.1 - 0.13 12.7 0.1 17 6.0 0.1 2.8 1 1 1 2 2 2 0 Leucine Rich repeats (2 copies) PseudoU_synth_2 PF00849.22 KIY66858.1 - 4.8e-28 98.3 0.2 7.1e-28 97.7 0.2 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase DUF2975 PF11188.8 KIY66859.1 - 0.0088 15.9 1.6 0.0088 15.9 1.6 3.1 2 1 0 2 2 2 1 Protein of unknown function (DUF2975) F-box-like PF12937.7 KIY66860.1 - 9.4e-09 35.0 2.4 1.9e-08 34.0 2.4 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY66860.1 - 0.033 14.1 0.2 0.088 12.7 0.2 1.8 1 0 0 1 1 1 0 F-box domain DUF2408 PF10303.9 KIY66861.1 - 5.2e-61 205.1 8.0 2.6e-41 141.4 0.1 4.9 4 1 0 4 4 4 4 Protein of unknown function (DUF2408) ParD_antitoxin PF03693.14 KIY66861.1 - 0.086 13.3 0.5 33 5.0 0.3 3.0 2 1 0 2 2 2 0 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH Snapin_Pallidin PF14712.6 KIY66861.1 - 0.14 12.6 11.2 8.2 6.9 0.0 5.6 6 1 0 6 6 6 0 Snapin/Pallidin Med9 PF07544.13 KIY66861.1 - 0.33 11.1 1.9 3.1 8.0 0.1 3.3 4 0 0 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 Baculo_PEP_C PF04513.12 KIY66861.1 - 4.2 7.4 6.9 3.9 7.5 1.4 3.1 3 1 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Tropomyosin_1 PF12718.7 KIY66862.1 - 6e-45 152.9 30.9 7.1e-45 152.7 30.9 1.0 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.20 KIY66862.1 - 1.1e-10 41.3 29.4 2.7e-05 23.7 9.1 3.0 1 1 2 3 3 3 3 Tropomyosin Uso1_p115_C PF04871.13 KIY66862.1 - 0.0017 18.7 15.0 0.0017 18.7 15.0 2.5 1 1 1 2 2 2 1 Uso1 / p115 like vesicle tethering protein, C terminal region DUF3450 PF11932.8 KIY66862.1 - 0.0061 15.9 23.9 0.15 11.4 9.3 2.1 1 1 0 2 2 2 2 Protein of unknown function (DUF3450) DUF724 PF05266.14 KIY66862.1 - 0.01 15.7 23.1 0.61 9.9 7.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) APG6_N PF17675.1 KIY66862.1 - 0.014 15.9 18.9 0.014 15.9 18.9 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region GAS PF13851.6 KIY66862.1 - 0.015 14.7 28.7 0.13 11.6 8.3 2.0 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF4200 PF13863.6 KIY66862.1 - 0.03 14.7 30.5 0.059 13.8 8.1 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) TPR_MLP1_2 PF07926.12 KIY66862.1 - 0.062 13.4 30.6 0.83 9.7 7.6 2.7 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Cep57_CLD_2 PF14197.6 KIY66862.1 - 0.069 13.2 26.6 0.5 10.5 3.8 3.6 1 1 1 3 3 3 0 Centrosome localisation domain of PPC89 DUF1664 PF07889.12 KIY66862.1 - 0.11 12.5 15.4 0.067 13.2 7.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Laminin_II PF06009.12 KIY66862.1 - 0.11 12.4 14.6 0.55 10.3 6.7 2.5 1 1 2 3 3 3 0 Laminin Domain II Alanine_zipper PF11839.8 KIY66862.1 - 0.2 12.0 9.5 0.19 12.1 2.3 2.9 2 1 1 3 3 3 0 Alanine-zipper, major outer membrane lipoprotein DUF4407 PF14362.6 KIY66862.1 - 0.22 10.8 18.6 0.3 10.4 18.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CENP-F_leu_zip PF10473.9 KIY66862.1 - 0.27 11.3 30.8 3.4 7.7 27.7 2.8 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Jnk-SapK_ap_N PF09744.9 KIY66862.1 - 0.29 11.4 30.0 0.068 13.4 17.0 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Tup_N PF08581.10 KIY66862.1 - 0.3 11.4 25.0 0.078 13.3 4.4 3.0 1 1 2 3 3 3 0 Tup N-terminal HMMR_N PF15905.5 KIY66862.1 - 0.32 10.4 29.0 0.74 9.2 29.0 1.5 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal DUF919 PF06034.11 KIY66862.1 - 0.45 10.4 16.9 0.067 13.0 6.0 2.8 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF919) CLZ PF16526.5 KIY66862.1 - 0.47 10.9 20.9 0.68 10.3 6.9 2.9 1 1 1 3 3 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels KxDL PF10241.9 KIY66862.1 - 0.49 10.7 16.0 2.6 8.4 4.6 2.8 2 1 1 3 3 3 0 Uncharacterized conserved protein Fib_alpha PF08702.10 KIY66862.1 - 0.55 10.4 15.8 0.073 13.2 7.5 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family EzrA PF06160.12 KIY66862.1 - 0.55 8.3 24.5 0.14 10.3 9.8 2.0 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA DUF5082 PF16888.5 KIY66862.1 - 0.58 10.4 17.9 0.37 11.1 11.1 3.4 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) Fez1 PF06818.15 KIY66862.1 - 0.68 10.3 24.9 1.7 9.0 12.5 2.0 1 1 1 2 2 2 0 Fez1 HrpB7 PF09486.10 KIY66862.1 - 0.75 10.2 19.5 4 7.8 4.0 2.6 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) BRE1 PF08647.11 KIY66862.1 - 0.8 9.8 23.4 0.5 10.5 11.0 3.0 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase Rootletin PF15035.6 KIY66862.1 - 1 9.4 23.2 0.44 10.5 13.0 2.2 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion DHR10 PF18595.1 KIY66862.1 - 1.2 9.2 30.3 2.1 8.4 9.5 2.8 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain Occludin_ELL PF07303.13 KIY66862.1 - 1.3 9.8 17.0 4.1 8.2 4.7 2.8 1 1 3 4 4 4 0 Occludin homology domain DUF3584 PF12128.8 KIY66862.1 - 1.3 6.4 24.4 1.8 6.0 24.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Flagellin_C PF00700.21 KIY66862.1 - 1.3 9.4 5.6 2.3 8.6 0.3 3.0 2 2 1 3 3 3 0 Bacterial flagellin C-terminal helical region AAA_13 PF13166.6 KIY66862.1 - 1.4 7.5 20.3 2 7.0 20.3 1.2 1 0 0 1 1 1 0 AAA domain BLOC1_2 PF10046.9 KIY66862.1 - 1.5 9.2 21.4 0.51 10.7 8.9 2.7 1 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ADIP PF11559.8 KIY66862.1 - 1.8 8.6 27.0 1.1 9.3 4.0 3.0 1 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Spc7 PF08317.11 KIY66862.1 - 2.3 7.0 29.3 10 4.9 14.8 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein NPV_P10 PF05531.12 KIY66862.1 - 2.4 8.7 10.3 38 4.8 4.3 3.6 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein UPF0242 PF06785.11 KIY66862.1 - 2.7 8.1 29.5 0.24 11.5 15.7 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus V_ATPase_I PF01496.19 KIY66862.1 - 2.9 5.7 14.2 3.6 5.4 14.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family T3SSipB PF16535.5 KIY66862.1 - 3.3 8.2 16.7 45 4.5 16.7 2.2 1 1 0 1 1 1 0 Type III cell invasion protein SipB Exonuc_VII_L PF02601.15 KIY66862.1 - 3.9 7.0 17.5 23 4.4 17.5 1.9 1 1 0 1 1 1 0 Exonuclease VII, large subunit PI3K_P85_iSH2 PF16454.5 KIY66862.1 - 4.3 6.9 22.9 18 4.9 23.0 1.7 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain FUSC PF04632.12 KIY66862.1 - 4.6 5.7 6.4 5 5.5 6.4 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Sec34 PF04136.15 KIY66862.1 - 5.3 6.9 15.2 0.48 10.3 6.3 2.3 1 1 0 2 2 2 0 Sec34-like family DegS PF05384.11 KIY66862.1 - 5.5 6.5 22.8 6 6.3 10.4 2.7 1 1 2 3 3 3 0 Sensor protein DegS DUF5320 PF17253.2 KIY66862.1 - 6.7 7.9 15.8 2.4 9.3 2.9 3.3 2 1 1 3 3 3 0 Family of unknown function (DUF5320) TMPIT PF07851.13 KIY66862.1 - 6.7 5.9 20.3 0.82 8.9 10.7 2.0 1 1 1 2 2 2 0 TMPIT-like protein NmrA PF05368.13 KIY66863.1 - 6.1e-17 62.0 0.1 8.3e-17 61.5 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KIY66863.1 - 4.4e-10 39.7 0.1 7.1e-10 39.1 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KIY66863.1 - 4.5e-06 27.0 0.2 8.3e-06 26.1 0.2 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KIY66863.1 - 0.00016 21.2 0.0 0.0034 16.9 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 KIY66863.1 - 0.00024 21.2 0.0 0.00044 20.3 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 KIY66863.1 - 0.00032 21.1 0.1 0.00054 20.4 0.1 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding TrkA_N PF02254.18 KIY66863.1 - 0.00038 20.7 0.4 0.0013 19.0 0.2 1.9 2 0 0 2 2 2 1 TrkA-N domain NAD_binding_2 PF03446.15 KIY66863.1 - 0.00081 19.6 0.0 0.0013 18.9 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KIY66863.1 - 0.00098 19.7 0.0 0.0031 18.1 0.0 1.9 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 KIY66863.1 - 0.0067 16.3 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KIY66863.1 - 0.01 15.2 0.4 0.028 13.7 0.1 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.16 KIY66863.1 - 0.035 13.7 0.0 0.094 12.4 0.0 1.8 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA adh_short PF00106.25 KIY66863.1 - 0.058 12.8 0.0 0.15 11.5 0.0 1.7 2 0 0 2 2 2 0 short chain dehydrogenase NAD_Gly3P_dh_N PF01210.23 KIY66863.1 - 0.073 13.0 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2-Hacid_dh_C PF02826.19 KIY66863.1 - 0.16 11.3 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Sacchrp_dh_C PF16653.5 KIY66865.1 - 6.4e-88 295.3 0.0 1.1e-87 294.6 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Spermine_synth PF01564.17 KIY66865.1 - 1.4e-66 223.5 0.0 2.7e-66 222.6 0.0 1.5 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 KIY66865.1 - 1e-24 86.1 1.2 1.9e-24 85.3 0.1 2.0 2 0 0 2 2 2 1 Spermidine synthase tetramerisation domain Sacchrp_dh_NADP PF03435.18 KIY66865.1 - 6.5e-22 78.2 2.3 1.8e-21 76.8 0.1 2.1 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Methyltransf_25 PF13649.6 KIY66865.1 - 1.2e-06 29.2 0.0 0.00026 21.6 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain Shikimate_DH PF01488.20 KIY66865.1 - 4.5e-06 26.8 0.0 2.6e-05 24.3 0.0 2.0 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 KIY66865.1 - 0.0041 17.0 0.1 0.0071 16.3 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Methyltransf_12 PF08242.12 KIY66865.1 - 0.0043 17.8 0.0 0.034 14.9 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.7 KIY66865.1 - 0.13 12.2 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Homeodomain PF00046.29 KIY66866.1 - 2.9e-19 68.7 0.9 4.6e-19 68.0 0.9 1.3 1 0 0 1 1 1 1 Homeodomain Pkinase PF00069.25 KIY66867.1 - 8.7e-46 156.4 0.0 1.2e-45 155.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY66867.1 - 8.2e-31 107.2 0.0 1.2e-30 106.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Fungal_trans PF04082.18 KIY66868.1 - 1.6e-18 66.7 0.0 2.3e-18 66.2 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY66868.1 - 5.8e-05 23.1 11.9 0.00011 22.3 11.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sec7 PF01369.20 KIY66870.1 - 4.8e-25 88.3 0.0 6.6e-25 87.9 0.0 1.2 1 0 0 1 1 1 1 Sec7 domain IQ_SEC7_PH PF16453.5 KIY66870.1 - 0.098 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 PH domain Peptidase_S41 PF03572.18 KIY66871.1 - 3.7e-06 26.6 0.0 8.2e-06 25.5 0.0 1.6 1 1 0 1 1 1 1 Peptidase family S41 DSPc PF00782.20 KIY66872.1 - 2.7e-26 92.0 0.0 3.9e-26 91.4 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KIY66872.1 - 0.0013 18.3 0.0 0.0022 17.6 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 KIY66872.1 - 0.062 13.0 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Pkinase PF00069.25 KIY66873.1 - 3.6e-39 134.7 0.0 5.8e-39 134.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY66873.1 - 3.8e-14 52.6 0.0 3.1e-12 46.4 0.0 2.6 2 1 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KIY66873.1 - 0.00039 20.4 1.6 0.0055 16.7 0.1 2.7 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KIY66873.1 - 0.0005 18.9 0.0 0.00072 18.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KIY66873.1 - 0.03 13.7 0.7 0.085 12.2 0.1 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KIY66873.1 - 0.041 13.2 0.0 2.2 7.5 0.0 2.2 2 0 0 2 2 2 0 Kinase-like DUF1679 PF07914.11 KIY66873.1 - 0.23 10.3 0.0 0.36 9.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) MIF4G PF02854.19 KIY66874.1 - 1.1e-48 165.6 3.3 1.2e-34 119.8 0.1 2.7 2 0 0 2 2 2 2 MIF4G domain Upf2 PF04050.14 KIY66874.1 - 5.7e-25 88.6 3.4 5.7e-25 88.6 3.4 3.0 1 1 1 2 2 2 1 Up-frameshift suppressor 2 DUF2457 PF10446.9 KIY66874.1 - 0.0079 15.4 16.9 0.017 14.3 16.9 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) SporV_AA PF12164.8 KIY66874.1 - 0.02 15.3 0.9 0.059 13.7 0.1 2.1 2 0 0 2 2 2 0 Stage V sporulation protein AA Mis12 PF05859.12 KIY66874.1 - 0.073 13.1 3.7 2.6 8.1 1.2 3.3 2 1 0 2 2 2 0 Mis12 protein NOA36 PF06524.12 KIY66874.1 - 1.4 8.2 12.5 2.7 7.2 12.5 1.4 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 KIY66874.1 - 1.9 9.0 21.3 2.7 8.5 19.1 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain FAM176 PF14851.6 KIY66874.1 - 4.2 7.0 6.8 16 5.1 6.8 2.0 1 0 0 1 1 1 0 FAM176 family Pes-10 PF07149.11 KIY66874.1 - 7.4 5.5 13.2 1.2 8.1 8.5 2.0 2 0 0 2 2 2 0 Pes-10 CDC45 PF02724.14 KIY66874.1 - 9.1 4.4 11.5 19 3.4 11.5 1.5 1 0 0 1 1 1 0 CDC45-like protein FAM76 PF16046.5 KIY66875.1 - 0.003 17.0 0.5 0.0054 16.1 0.5 1.4 1 0 0 1 1 1 1 FAM76 protein DUF4386 PF14329.6 KIY66875.1 - 0.14 12.0 0.1 0.24 11.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4386) CEP63 PF17045.5 KIY66875.1 - 0.39 10.6 13.8 0.6 10.0 13.8 1.2 1 0 0 1 1 1 0 Centrosomal protein of 63 kDa Cortex-I_coil PF09304.10 KIY66875.1 - 0.89 9.8 10.1 1.8 8.8 10.1 1.4 1 0 0 1 1 1 0 Cortexillin I, coiled coil CENP-H PF05837.12 KIY66875.1 - 1.5 9.3 13.0 2.9 8.3 13.0 1.5 1 0 0 1 1 1 0 Centromere protein H (CENP-H) NPV_P10 PF05531.12 KIY66875.1 - 1.5 9.4 4.0 6.1 7.4 0.7 2.8 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein PRP1_N PF06424.12 KIY66875.1 - 6 7.3 9.5 39 4.6 0.1 2.5 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal DUF1664 PF07889.12 KIY66875.1 - 6 6.9 7.8 12 5.9 7.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF4407 PF14362.6 KIY66875.1 - 8.4 5.6 9.4 14 4.9 9.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Aldo_ket_red PF00248.21 KIY66876.1 - 1.1e-66 225.1 0.1 1.2e-66 224.9 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HAD_2 PF13419.6 KIY66877.1 - 1.2e-12 48.3 0.0 1.6e-12 47.9 0.0 1.3 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KIY66877.1 - 3.9e-12 46.9 0.0 5.2e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KIY66877.1 - 1.4e-06 28.3 0.0 2.7e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like PqqD PF05402.12 KIY66877.1 - 0.011 16.0 0.0 0.019 15.2 0.0 1.4 1 0 0 1 1 1 0 Coenzyme PQQ synthesis protein D (PqqD) MAP17 PF15807.5 KIY66878.1 - 0.016 15.5 4.1 0.021 15.0 0.1 2.0 1 1 1 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DUF966 PF06136.13 KIY66878.1 - 1.8 8.2 9.8 2 8.1 9.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DUF4674 PF15719.5 KIY66878.1 - 3.7 7.6 6.1 5.1 7.1 6.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4674) Presenilin PF01080.17 KIY66878.1 - 9.8 4.8 10.6 14 4.3 10.6 1.3 1 0 0 1 1 1 0 Presenilin Hid1 PF12722.7 KIY66878.1 - 9.8 4.2 9.4 11 4.0 9.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Zip PF02535.22 KIY66878.1 - 9.9 5.3 8.0 17 4.5 8.0 1.4 1 1 0 1 1 1 0 ZIP Zinc transporter SNase PF00565.17 KIY66879.1 - 1.8e-57 192.5 0.1 3.3e-16 59.7 0.0 6.1 5 1 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.24 KIY66879.1 - 2.4e-20 72.8 0.0 4.2e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 Tudor domain Agenet PF05641.12 KIY66879.1 - 0.007 16.8 0.1 0.059 13.8 0.0 2.7 3 0 0 3 3 3 1 Agenet domain GDC-P PF02347.16 KIY66880.1 - 9.7e-181 601.3 0.0 2.9e-170 566.8 0.0 2.8 3 0 0 3 3 3 2 Glycine cleavage system P-protein Aminotran_5 PF00266.19 KIY66880.1 - 1.8e-05 23.9 0.0 7.1e-05 21.9 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KIY66880.1 - 0.00042 19.7 0.0 0.0008 18.8 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Form_Nir_trans PF01226.17 KIY66881.1 - 7.6e-76 254.5 20.5 8.9e-76 254.3 20.5 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter RRM_2 PF04059.12 KIY66882.1 - 3.2e-34 117.0 0.9 4.1e-34 116.7 0.9 1.1 1 0 0 1 1 1 1 RNA recognition motif 2 BRAP2 PF07576.12 KIY66882.1 - 0.0015 18.7 0.3 0.0023 18.1 0.3 1.3 1 1 0 1 1 1 1 BRCA1-associated protein 2 RRM_1 PF00076.22 KIY66882.1 - 0.022 14.6 0.0 0.039 13.8 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_S6 PF01250.17 KIY66884.1 - 8.7e-25 86.8 0.0 1.1e-24 86.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 LETM1 PF07766.13 KIY66885.1 - 8.1e-13 48.3 0.1 3.1e-09 36.6 0.0 2.1 1 1 1 2 2 2 2 LETM1-like protein adh_short_C2 PF13561.6 KIY66886.1 - 1e-55 188.9 3.2 1.2e-55 188.6 3.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIY66886.1 - 7.9e-42 142.9 2.2 1.1e-41 142.5 2.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIY66886.1 - 1.9e-10 41.0 3.2 4.3e-10 39.8 3.2 1.5 1 1 0 1 1 1 1 KR domain ThiF PF00899.21 KIY66886.1 - 0.0071 15.7 0.4 0.038 13.3 0.4 2.2 1 1 0 1 1 1 1 ThiF family Methyltransf_25 PF13649.6 KIY66886.1 - 0.042 14.5 0.0 0.12 13.1 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Cpn60_TCP1 PF00118.24 KIY66887.1 - 1.2e-162 541.9 0.8 1.5e-162 541.6 0.8 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Utp14 PF04615.13 KIY66888.1 - 0.2 10.2 3.7 0.22 10.0 3.7 1.1 1 0 0 1 1 1 0 Utp14 protein DUF5585 PF17823.1 KIY66888.1 - 0.43 9.5 56.8 0.64 8.9 56.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5585) Hamartin PF04388.12 KIY66888.1 - 3 6.4 21.9 3.9 6.0 21.9 1.0 1 0 0 1 1 1 0 Hamartin protein PRCC PF10253.9 KIY66888.1 - 4.4 8.0 18.5 0.34 11.7 12.8 1.9 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting SOG2 PF10428.9 KIY66888.1 - 9.5 5.3 28.3 13 4.8 28.3 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein E1-E2_ATPase PF00122.20 KIY66889.1 - 8.8e-32 110.1 0.0 2.3e-31 108.7 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase P5-ATPase PF12409.8 KIY66889.1 - 1.5e-25 89.7 0.0 3.3e-25 88.6 0.0 1.6 1 0 0 1 1 1 1 P5-type ATPase cation transporter Hydrolase PF00702.26 KIY66889.1 - 1.6e-18 67.8 0.6 1.1e-08 35.7 0.1 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 KIY66889.1 - 9.9e-07 28.6 3.6 2.7e-06 27.2 3.6 1.7 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 KIY66889.1 - 1.2e-05 25.3 0.0 2.8e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KIY66889.1 - 0.0047 16.6 0.0 0.01 15.5 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus CARMIL_C PF16000.5 KIY66889.1 - 0.062 12.9 4.2 0.097 12.3 4.2 1.2 1 0 0 1 1 1 0 CARMIL C-terminus Hydrolase_3 PF08282.12 KIY66889.1 - 0.23 11.1 0.0 0.37 10.5 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase ABC_tran PF00005.27 KIY66891.1 - 1.5e-43 148.6 0.0 7.9e-24 84.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KIY66891.1 - 3.4e-41 141.7 30.3 1.9e-23 83.5 10.4 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 KIY66891.1 - 8.3e-11 41.7 0.3 0.041 13.3 0.0 4.2 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 KIY66891.1 - 3.1e-07 30.2 0.0 0.011 15.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 KIY66891.1 - 4.3e-07 30.6 0.6 0.00019 22.0 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KIY66891.1 - 3.1e-06 27.2 0.2 0.027 14.3 0.0 3.4 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system T2SSE PF00437.20 KIY66891.1 - 1.1e-05 24.7 0.0 0.0012 18.0 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_29 PF13555.6 KIY66891.1 - 2.4e-05 24.0 2.8 0.019 14.7 0.1 3.2 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KIY66891.1 - 2.6e-05 24.7 0.3 0.087 13.2 0.0 2.7 2 1 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KIY66891.1 - 9.6e-05 22.3 0.1 0.066 13.1 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 KIY66891.1 - 0.00049 20.4 0.7 0.28 11.5 0.0 3.3 2 1 0 2 2 2 1 AAA domain cobW PF02492.19 KIY66891.1 - 0.00053 19.6 1.5 0.0052 16.4 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 KIY66891.1 - 0.00065 19.8 0.1 0.55 10.3 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF87 PF01935.17 KIY66891.1 - 0.00078 19.6 0.6 0.016 15.3 0.2 2.3 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_30 PF13604.6 KIY66891.1 - 0.0017 18.1 0.3 0.14 11.9 0.0 3.4 4 0 0 4 4 4 1 AAA domain IstB_IS21 PF01695.17 KIY66891.1 - 0.0029 17.4 0.1 2.9 7.6 0.0 3.0 3 0 0 3 3 2 1 IstB-like ATP binding protein AAA_7 PF12775.7 KIY66891.1 - 0.0029 17.1 0.0 0.25 10.8 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region NACHT PF05729.12 KIY66891.1 - 0.0038 17.1 0.4 0.53 10.2 0.0 2.7 2 0 0 2 2 2 1 NACHT domain ResIII PF04851.15 KIY66891.1 - 0.0048 16.9 0.0 0.28 11.2 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit FtsK_SpoIIIE PF01580.18 KIY66891.1 - 0.0058 16.0 0.2 1 8.7 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family RecA PF00154.21 KIY66891.1 - 0.0069 15.9 0.2 0.87 9.0 0.0 2.8 3 0 0 3 3 3 1 recA bacterial DNA recombination protein AAA_18 PF13238.6 KIY66891.1 - 0.0077 16.8 0.0 2.7 8.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 KIY66891.1 - 0.0081 15.4 0.1 0.14 11.3 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) DEAD PF00270.29 KIY66891.1 - 0.0082 15.9 0.6 11 5.7 0.0 3.2 2 1 0 2 2 2 0 DEAD/DEAH box helicase PhoH PF02562.16 KIY66891.1 - 0.011 15.2 0.1 0.65 9.4 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein TrwB_AAD_bind PF10412.9 KIY66891.1 - 0.012 14.5 0.1 4.1 6.2 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Pox_A32 PF04665.12 KIY66891.1 - 0.017 14.6 0.1 2.5 7.5 0.0 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_5 PF07728.14 KIY66891.1 - 0.029 14.4 0.6 14 5.6 0.0 3.1 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_15 PF13175.6 KIY66891.1 - 0.042 13.6 0.1 0.3 10.7 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain Adeno_IVa2 PF02456.15 KIY66891.1 - 0.044 12.6 0.1 0.95 8.2 0.0 2.1 2 0 0 2 2 2 0 Adenovirus IVa2 protein ATPase_2 PF01637.18 KIY66891.1 - 0.048 13.6 0.0 0.42 10.5 0.0 2.4 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 KIY66891.1 - 0.068 12.9 0.0 11 5.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KIY66891.1 - 0.087 13.2 0.1 25 5.3 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Dynamin_N PF00350.23 KIY66891.1 - 0.12 12.4 0.3 22 5.1 0.1 2.4 2 0 0 2 2 2 0 Dynamin family SbcCD_C PF13558.6 KIY66891.1 - 0.13 12.5 0.5 4 7.8 0.2 2.9 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit ATPase PF06745.13 KIY66891.1 - 0.14 11.5 0.2 2.5 7.4 0.0 2.2 2 0 0 2 2 2 0 KaiC AAA PF00004.29 KIY66891.1 - 0.16 12.4 0.1 2.2 8.7 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KIY66891.1 - 0.17 12.1 0.6 6.6 6.9 0.1 2.7 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KIY66891.1 - 0.17 11.8 0.3 6.8 6.6 0.1 3.0 3 0 0 3 3 3 0 NTPase Nop25 PF09805.9 KIY66892.1 - 6.3e-22 78.5 16.4 6.3e-22 78.5 16.4 2.3 2 0 0 2 2 2 1 Nucleolar protein 12 (25kDa) DUF4551 PF15087.6 KIY66892.1 - 6.4 5.5 9.3 7.8 5.2 9.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Nexin_C PF08628.12 KIY66892.1 - 8.7 7.0 7.8 0.41 11.2 1.3 2.0 3 0 0 3 3 3 0 Sorting nexin C terminal FAM72 PF14976.6 KIY66893.1 - 2.3e-15 57.0 6.4 2.2e-14 53.8 6.4 2.0 1 1 0 1 1 1 1 FAM72 protein V-SNARE_C PF12352.8 KIY66894.1 - 4.9e-16 58.8 1.0 1.1e-15 57.6 1.0 1.6 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 KIY66894.1 - 1.8e-06 27.7 1.3 9.8e-06 25.4 0.0 2.2 2 0 0 2 2 2 1 Sec20 THOC7 PF05615.13 KIY66894.1 - 0.019 15.3 6.8 0.049 13.9 6.8 1.8 1 1 0 1 1 1 0 Tho complex subunit 7 Prefoldin_2 PF01920.20 KIY66894.1 - 0.03 14.3 4.0 0.12 12.3 3.4 2.0 2 0 0 2 2 2 0 Prefoldin subunit NDUF_C2 PF06374.11 KIY66894.1 - 0.15 12.2 0.0 1.7 8.9 0.0 2.2 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) JAKMIP_CC3 PF16034.5 KIY66894.1 - 0.18 11.7 5.4 0.25 11.3 5.2 1.6 1 1 0 1 1 1 0 JAKMIP CC3 domain Lactamase_B PF00753.27 KIY66895.1 - 4.3e-06 26.9 0.1 7.4e-06 26.1 0.1 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KIY66895.1 - 7.3e-05 22.4 0.0 0.00015 21.3 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain ubiquitin PF00240.23 KIY66896.1 - 1.5e-170 553.2 25.4 1.9e-33 114.0 0.5 5.0 5 0 0 5 5 5 5 Ubiquitin family Rad60-SLD PF11976.8 KIY66896.1 - 2.6e-78 257.8 27.8 4.3e-15 55.3 0.6 5.0 5 0 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KIY66896.1 - 3e-28 98.1 12.9 0.00064 20.1 0.1 6.9 5 5 0 5 5 5 5 Ubiquitin-like domain TBK1_ULD PF18396.1 KIY66896.1 - 1.7e-19 69.6 5.6 0.047 13.6 0.0 5.2 5 0 0 5 5 5 5 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 KIY66896.1 - 1.2e-17 64.0 4.5 0.16 12.1 0.0 6.0 5 4 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 KIY66896.1 - 2.7e-17 62.9 12.0 0.063 13.6 0.1 5.1 5 0 0 5 5 5 5 Ubiquitin-like domain DUF2407 PF10302.9 KIY66896.1 - 5.6e-16 59.0 2.3 0.49 11.0 0.0 5.2 1 1 1 5 5 5 5 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 KIY66896.1 - 3.9e-12 46.3 0.7 1.8 8.4 0.0 5.1 1 1 4 5 5 5 5 Silencing defective 2 N-terminal ubiquitin domain Methyltrans_RNA PF04452.14 KIY66896.1 - 3.7e-09 36.2 1.8 1.4 8.2 0.0 4.2 4 0 0 4 4 4 4 RNA methyltransferase Ubiquitin_4 PF18036.1 KIY66896.1 - 1.2e-07 31.7 32.7 21 5.2 0.2 9.9 10 0 0 10 10 10 0 Ubiquitin-like domain Big_7 PF17957.1 KIY66896.1 - 1.6e-07 32.0 0.6 41 5.0 0.0 5.1 5 0 0 5 5 5 0 Bacterial Ig domain DUF2870 PF11069.8 KIY66896.1 - 1.9e-07 31.3 0.0 40 4.7 0.0 5.8 5 0 0 5 5 5 0 Protein of unknown function (DUF2870) TmoB PF06234.12 KIY66896.1 - 4.7e-07 29.8 0.1 40 4.4 0.0 5.8 5 0 0 5 5 5 0 Toluene-4-monooxygenase system protein B (TmoB) DUF3861 PF12977.7 KIY66896.1 - 5.8e-07 29.6 5.6 18 5.6 0.0 5.2 5 0 0 5 5 5 0 Domain of Unknown Function with PDB structure (DUF3861) ACT_5 PF13710.6 KIY66896.1 - 1.2e-06 28.2 6.5 15 5.5 0.0 5.3 5 0 0 5 5 5 0 ACT domain UDP-g_GGTase PF06427.11 KIY66896.1 - 4.3e-06 26.8 6.0 9.6 6.4 0.0 4.9 5 0 0 5 5 5 0 UDP-glucose:Glycoprotein Glucosyltransferase DUF969 PF06149.12 KIY66896.1 - 2.5e-05 23.8 0.2 29 4.0 0.0 4.8 5 0 0 5 5 5 0 Protein of unknown function (DUF969) ACT_4 PF13291.6 KIY66896.1 - 6e-05 23.6 2.2 97 3.7 0.0 5.2 5 0 0 5 5 5 0 ACT domain DUF493 PF04359.14 KIY66896.1 - 0.00037 21.0 0.1 1.9e+02 2.7 0.0 4.9 5 0 0 5 5 5 0 Protein of unknown function (DUF493) ORF11CD3 PF10549.9 KIY66896.1 - 0.00069 19.7 0.0 1.2e+02 2.9 0.0 5.1 5 0 0 5 5 5 0 ORF11CD3 domain ProRS-C_2 PF09181.10 KIY66896.1 - 0.008 16.3 8.5 85 3.4 0.1 5.1 5 0 0 5 5 5 0 Prolyl-tRNA synthetase, C-terminal FlgD_ig PF13860.6 KIY66896.1 - 0.052 13.4 13.5 57 3.7 0.1 5.3 5 0 0 5 5 5 0 FlgD Ig-like domain Tash_PEST PF07708.11 KIY66896.1 - 0.19 11.9 36.0 8 6.8 1.4 5.3 5 0 0 5 5 5 0 Tash protein PEST motif Phage_sheath_1N PF17481.2 KIY66896.1 - 0.47 11.0 12.5 1e+02 3.5 0.1 4.9 1 1 1 3 3 3 0 Phage tail sheath protein beta-sandwich domain YcgR_2 PF12945.7 KIY66896.1 - 2.4 8.4 7.6 3.2e+02 1.6 0.0 4.8 5 0 0 5 5 5 0 Flagellar protein YcgR PI3K_p85B PF02192.16 KIY66896.1 - 3 7.6 12.6 1.3e+02 2.5 0.1 5.1 5 0 0 5 5 5 0 PI3-kinase family, p85-binding domain Cnl2_NKP2 PF09447.10 KIY66896.1 - 3.1 8.0 14.4 1.3e+02 2.8 0.1 5.3 5 0 0 5 5 5 0 Cnl2/NKP2 family protein Ribosomal_S4e PF00900.20 KIY66896.1 - 5.8 6.9 11.7 1.7e+02 2.2 0.1 5.6 5 0 0 5 5 5 0 Ribosomal family S4e Pkinase PF00069.25 KIY66897.1 - 7.1e-61 205.9 0.0 1.1e-60 205.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY66897.1 - 7.3e-26 91.0 0.0 7.4e-15 54.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.24 KIY66897.1 - 4.9e-05 23.9 6.9 4.9e-05 23.9 6.9 3.8 3 0 0 3 3 3 1 Protein kinase C terminal domain APH PF01636.23 KIY66897.1 - 0.0087 16.0 1.5 1.7 8.5 0.3 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KIY66897.1 - 0.018 14.4 0.0 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KIY66897.1 - 0.021 14.1 0.2 2 7.6 0.0 2.6 3 0 0 3 3 3 0 Kinase-like FTA2 PF13095.6 KIY66897.1 - 0.056 13.1 0.0 5.9 6.4 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Rhodanese PF00581.20 KIY66898.1 - 4.9e-06 27.0 0.0 1e-05 26.0 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Transferase PF02458.15 KIY66900.1 - 6e-07 28.5 0.2 4.1e-06 25.7 0.0 2.1 2 1 0 2 2 2 1 Transferase family DUF3136 PF11334.8 KIY66900.1 - 0.087 12.6 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3136) Sugar_tr PF00083.24 KIY66901.1 - 2.3e-93 313.5 19.5 2.6e-93 313.3 19.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY66901.1 - 3e-24 85.6 27.0 3e-24 85.6 27.0 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 KIY66901.1 - 5.3e-05 21.7 0.4 5.3e-05 21.7 0.4 2.3 1 1 1 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family DUF1211 PF06736.11 KIY66901.1 - 0.0096 16.3 4.5 0.052 14.0 4.5 2.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1211) Ribosomal_S12 PF17487.2 KIY66901.1 - 0.025 15.3 0.3 0.025 15.3 0.3 2.3 2 0 0 2 2 2 0 Ribosomal protein S12 DUF3767 PF12597.8 KIY66901.1 - 0.2 11.5 1.0 0.75 9.6 1.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3767) Sugar_tr PF00083.24 KIY66902.1 - 2.5e-97 326.6 19.0 2.9e-97 326.4 19.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY66902.1 - 1.9e-27 96.1 28.5 4e-27 95.1 23.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KIY66902.1 - 3.6e-07 28.9 0.9 3.6e-07 28.9 0.9 2.6 1 1 2 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family DUF1129 PF06570.11 KIY66902.1 - 0.031 13.8 0.6 0.031 13.8 0.6 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1129) DUF1211 PF06736.11 KIY66902.1 - 0.13 12.8 3.2 0.39 11.2 3.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1211) Ribosomal_S12 PF17487.2 KIY66902.1 - 0.27 12.0 0.2 0.27 12.0 0.2 2.7 2 0 0 2 2 2 0 Ribosomal protein S12 AhpC-TSA PF00578.21 KIY66903.1 - 2.3e-16 59.8 0.0 2.3e-10 40.5 0.0 2.0 2 0 0 2 2 2 2 AhpC/TSA family Redoxin PF08534.10 KIY66903.1 - 8e-07 28.9 0.0 6.9e-06 25.8 0.0 1.9 1 1 0 1 1 1 1 Redoxin Pyridoxal_deC PF00282.19 KIY66904.1 - 2.3e-101 339.2 0.0 2.8e-101 339.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KIY66904.1 - 0.007 15.4 0.0 0.011 14.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V IGPS PF00218.21 KIY66905.1 - 1.2e-89 299.9 0.0 1.3e-89 299.7 0.0 1.0 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase QRPTase_C PF01729.19 KIY66905.1 - 0.00045 20.0 0.4 0.00089 19.1 0.4 1.5 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain NanE PF04131.14 KIY66905.1 - 0.019 14.2 0.1 0.046 12.9 0.1 1.7 1 1 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase His_biosynth PF00977.21 KIY66905.1 - 0.023 14.2 0.0 0.059 12.8 0.0 1.7 2 0 0 2 2 2 0 Histidine biosynthesis protein WD40 PF00400.32 KIY66907.1 - 2.1e-35 120.1 24.2 2.5e-07 31.3 0.0 7.9 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY66907.1 - 2.5e-07 30.9 0.1 0.00092 19.5 0.0 3.4 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIY66907.1 - 9.8e-07 27.8 1.4 0.01 14.5 0.0 4.1 4 1 1 5 5 5 2 Nucleoporin Nup120/160 F-box-like PF12937.7 KIY66907.1 - 1.9e-06 27.6 0.2 4.2e-06 26.6 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY66907.1 - 0.018 14.9 1.4 0.06 13.2 1.4 1.9 1 1 0 1 1 1 0 F-box domain CDtoxinA PF03498.14 KIY66907.1 - 0.059 12.9 0.0 0.42 10.2 0.0 2.2 2 0 0 2 2 2 0 Cytolethal distending toxin A/C domain Ge1_WD40 PF16529.5 KIY66907.1 - 0.084 11.8 1.1 7.9 5.3 0.2 3.4 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KIY66907.1 - 0.17 11.2 0.0 0.43 9.9 0.0 1.8 2 0 0 2 2 2 0 WD40-like domain AIG1 PF04548.16 KIY66908.1 - 2.1e-07 30.5 0.2 2.1e-07 30.5 0.2 2.5 3 1 0 3 3 3 1 AIG1 family Septin PF00735.18 KIY66908.1 - 9.4e-05 21.8 0.0 0.0002 20.7 0.0 1.5 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KIY66908.1 - 0.00029 20.9 0.0 0.001 19.2 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIY66908.1 - 0.0092 15.9 0.8 0.28 11.1 0.0 2.7 3 0 0 3 3 3 1 RsgA GTPase PLU-1 PF08429.11 KIY66908.1 - 0.0097 15.1 8.4 0.051 12.8 8.4 1.9 1 1 0 1 1 1 1 PLU-1-like protein Ras PF00071.22 KIY66908.1 - 0.015 14.9 0.2 0.16 11.5 0.0 2.4 2 0 0 2 2 2 0 Ras family Roc PF08477.13 KIY66908.1 - 0.038 14.2 0.0 0.16 12.2 0.0 2.2 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_5 PF07728.14 KIY66908.1 - 0.06 13.4 0.0 0.17 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Metal_resist PF13801.6 KIY66908.1 - 0.066 13.4 3.7 0.095 12.9 2.4 1.9 1 1 0 1 1 1 0 Heavy-metal resistance AAA_33 PF13671.6 KIY66908.1 - 0.082 13.1 1.2 5.5 7.1 0.0 3.2 4 0 0 4 4 4 0 AAA domain AAA_23 PF13476.6 KIY66908.1 - 0.083 13.4 6.5 0.11 13.0 0.7 2.9 2 1 0 2 2 2 0 AAA domain Pox_A32 PF04665.12 KIY66908.1 - 0.11 12.0 0.3 0.29 10.6 0.0 1.8 2 0 0 2 2 2 0 Poxvirus A32 protein Dynamin_N PF00350.23 KIY66908.1 - 0.74 9.9 0.0 0.74 9.9 0.0 2.6 3 1 0 3 3 3 0 Dynamin family DUF4854 PF16146.5 KIY66908.1 - 7.4 7.0 9.0 17 5.8 0.1 3.7 3 1 1 4 4 4 0 Domain of unknown function (DUF4854) adh_short PF00106.25 KIY66909.1 - 4.6e-41 140.4 0.5 6.6e-41 139.9 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIY66909.1 - 9.8e-23 80.9 0.1 1.4e-22 80.4 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIY66909.1 - 0.00054 19.9 0.1 0.0013 18.7 0.1 1.6 1 1 0 1 1 1 1 KR domain Pyr_redox_2 PF07992.14 KIY66909.1 - 0.0091 15.3 0.1 0.022 14.0 0.1 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Glyco_tran_WecB PF03808.13 KIY66909.1 - 0.048 13.6 0.0 0.19 11.7 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family zf-H2C2_2 PF13465.6 KIY66910.1 - 0.0042 17.4 2.3 0.021 15.2 0.5 2.4 2 0 0 2 2 2 1 Zinc-finger double domain Lar_restr_allev PF14354.6 KIY66910.1 - 0.033 14.6 0.2 0.062 13.7 0.2 1.5 1 0 0 1 1 1 0 Restriction alleviation protein Lar Zn_Tnp_IS1595 PF12760.7 KIY66910.1 - 0.055 13.5 0.4 0.089 12.8 0.4 1.3 1 0 0 1 1 1 0 Transposase zinc-ribbon domain PHD_Oberon PF07227.11 KIY66910.1 - 0.11 12.3 0.1 0.16 11.8 0.1 1.1 1 0 0 1 1 1 0 PHD - plant homeodomain finger protein Vps36-NZF-N PF16988.5 KIY66910.1 - 1 8.8 4.4 0.73 9.3 1.0 2.2 1 1 1 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain MRG PF05712.13 KIY66911.1 - 8.3e-53 178.6 0.5 8.3e-53 178.6 0.5 1.4 2 0 0 2 2 2 1 MRG Tudor-knot PF11717.8 KIY66911.1 - 7.5e-10 38.6 1.2 1.6e-09 37.5 0.9 1.8 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain Chromo PF00385.24 KIY66911.1 - 0.0057 16.5 1.5 0.016 15.1 1.5 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain YchF-GTPase_C PF06071.13 KIY66912.1 - 5.1e-34 116.3 0.4 1.7e-33 114.7 0.1 2.1 3 0 0 3 3 3 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 KIY66912.1 - 8.6e-20 70.9 0.0 2e-19 69.7 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KIY66912.1 - 4.4e-07 29.5 0.0 9.2e-07 28.5 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B MeaB PF03308.16 KIY66912.1 - 0.004 16.2 0.5 0.03 13.3 0.0 2.2 2 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Methyltransf_2 PF00891.18 KIY66913.1 - 9.5e-19 67.5 0.0 1.2e-17 63.9 0.0 2.1 1 1 0 1 1 1 1 O-methyltransferase domain Methyltransf_12 PF08242.12 KIY66913.1 - 0.00027 21.6 0.0 0.00063 20.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIY66913.1 - 0.00085 20.0 0.0 0.002 18.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIY66913.1 - 0.05 13.4 0.0 0.099 12.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 KIY66913.1 - 0.066 13.0 0.0 0.17 11.7 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KIY66913.1 - 0.08 12.5 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_4 PF02390.17 KIY66913.1 - 0.13 11.7 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_2 PF00891.18 KIY66914.1 - 4.8e-21 75.0 0.2 7.5e-20 71.1 0.2 2.1 1 1 0 1 1 1 1 O-methyltransferase domain Methyltransf_12 PF08242.12 KIY66914.1 - 0.0011 19.7 0.0 0.0031 18.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIY66914.1 - 0.0012 18.7 0.0 0.0026 17.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIY66914.1 - 0.0023 18.6 0.0 0.0065 17.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_5 PF01795.19 KIY66914.1 - 0.024 14.1 0.0 0.15 11.5 0.0 2.0 2 0 0 2 2 2 0 MraW methylase family MTS PF05175.14 KIY66914.1 - 0.038 13.5 0.0 0.085 12.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain HTH_AraC PF00165.23 KIY66914.1 - 0.046 13.8 0.0 0.1 12.8 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family Glyco_hydro_92 PF07971.12 KIY66915.1 - 3.3e-133 445.0 0.5 3.9e-133 444.7 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 KIY66915.1 - 9.4e-56 189.4 2.3 1.6e-55 188.6 0.4 2.1 2 1 0 2 2 2 1 Glycosyl hydrolase family 92 N-terminal domain Dockerin_1 PF00404.18 KIY66915.1 - 0.034 14.3 0.0 0.18 12.0 0.0 2.1 2 0 0 2 2 2 0 Dockerin type I domain FGE-sulfatase PF03781.16 KIY66916.1 - 3e-19 69.6 2.5 7.4e-11 42.1 0.2 2.2 2 0 0 2 2 2 2 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 KIY66916.1 - 1e-07 32.5 1.8 2.2e-07 31.4 1.8 1.6 1 0 0 1 1 1 1 DinB superfamily NAD_binding_10 PF13460.6 KIY66917.1 - 1e-08 35.3 1.8 0.003 17.5 0.8 2.3 1 1 1 2 2 2 2 NAD(P)H-binding NmrA PF05368.13 KIY66917.1 - 1.8e-08 34.2 0.1 3.9e-08 33.1 0.1 1.5 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 KIY66917.1 - 4.4e-05 22.8 0.1 0.0025 17.0 0.1 2.2 1 1 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 KIY66917.1 - 0.0054 16.2 0.1 0.06 12.8 0.1 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 KIY66917.1 - 0.0067 16.6 0.3 0.18 11.9 0.3 2.3 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Sacchrp_dh_NADP PF03435.18 KIY66917.1 - 0.011 16.0 0.2 0.04 14.2 0.2 1.9 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain ATP_bind_2 PF03668.15 KIY66917.1 - 0.036 13.4 0.0 0.053 12.8 0.0 1.2 1 0 0 1 1 1 0 P-loop ATPase protein family Semialdhyde_dh PF01118.24 KIY66917.1 - 0.059 13.8 0.3 0.33 11.4 0.2 2.2 1 1 1 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 KIY66918.1 - 8.8e-10 38.8 0.1 0.0011 18.9 0.1 2.2 1 1 1 2 2 2 2 NAD(P)H-binding NmrA PF05368.13 KIY66918.1 - 1.6e-08 34.4 0.1 3e-08 33.5 0.1 1.4 1 1 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 KIY66918.1 - 0.01 15.0 0.0 0.03 13.5 0.0 1.7 1 1 1 2 2 2 0 Male sterility protein Sacchrp_dh_NADP PF03435.18 KIY66918.1 - 0.014 15.6 0.1 0.051 13.8 0.1 1.9 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Yae1_N PF09811.9 KIY66919.1 - 1.5e-09 37.4 3.1 2.6e-09 36.6 3.1 1.4 1 0 0 1 1 1 1 Essential protein Yae1, N terminal ADH_N PF08240.12 KIY66921.1 - 2.2e-21 75.8 0.4 3.9e-21 75.0 0.4 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KIY66921.1 - 2e-11 44.0 0.0 4.3e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KIY66921.1 - 9.4e-05 21.8 0.0 0.00015 21.2 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KIY66921.1 - 0.00025 20.4 0.1 0.0013 18.1 0.0 2.0 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 KIY66921.1 - 0.0098 16.1 0.5 0.045 13.9 0.1 2.1 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NADH_4Fe-4S PF10589.9 KIY66921.1 - 0.15 12.1 1.6 0.24 11.5 0.6 1.8 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region GMC_oxred_N PF00732.19 KIY66922.1 - 1.6e-61 208.3 0.0 2e-61 208.0 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIY66922.1 - 4.4e-33 114.8 0.1 8e-33 114.0 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_3 PF13738.6 KIY66922.1 - 0.00075 18.8 0.0 0.53 9.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KIY66922.1 - 0.003 16.7 0.1 0.0064 15.6 0.1 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KIY66922.1 - 0.0038 16.5 0.1 0.25 10.5 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIY66922.1 - 0.0042 16.7 1.2 0.051 13.1 0.5 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KIY66922.1 - 0.0076 15.5 0.1 0.013 14.7 0.1 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 KIY66922.1 - 0.0078 16.4 0.3 0.02 15.1 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KIY66922.1 - 0.0081 15.3 0.2 0.27 10.3 0.1 2.3 2 0 0 2 2 2 1 FAD binding domain Glyco_hydro_28 PF00295.17 KIY66923.1 - 2.3e-72 243.8 19.2 2.9e-72 243.5 19.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Chlam_PMP PF02415.17 KIY66923.1 - 0.28 11.8 4.0 24 5.7 1.3 3.5 2 1 0 2 2 2 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat BTB PF00651.31 KIY66924.1 - 1.7e-06 28.2 0.0 3.1e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Phage_TAC_12 PF12363.8 KIY66924.1 - 0.021 15.2 0.0 0.035 14.5 0.0 1.3 1 0 0 1 1 1 0 Phage tail assembly chaperone protein, TAC Glucosamine_iso PF01182.20 KIY66925.1 - 1.7e-18 67.3 0.0 2.8e-18 66.6 0.0 1.4 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase FAD_binding_8 PF08022.12 KIY66925.1 - 0.053 13.6 0.0 0.093 12.8 0.0 1.3 1 0 0 1 1 1 0 FAD-binding domain UPF0029 PF01205.19 KIY66926.1 - 1.4e-22 80.0 0.0 1.9e-22 79.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 GMC_oxred_N PF00732.19 KIY66928.1 - 7e-56 189.8 0.0 8.9e-56 189.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIY66928.1 - 1.8e-31 109.6 0.0 2.8e-31 109.0 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KIY66928.1 - 0.014 14.4 0.2 0.026 13.6 0.2 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 KIY66928.1 - 0.022 13.9 0.5 1.5 7.8 0.0 2.3 2 0 0 2 2 2 0 FAD binding domain NAD_binding_8 PF13450.6 KIY66928.1 - 0.078 13.2 1.3 0.25 11.6 0.3 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KIY66928.1 - 0.18 11.0 0.0 0.34 10.1 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Glyco_hydro_35 PF01301.19 KIY66929.1 - 1.4e-74 251.6 0.1 2.1e-74 251.0 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 KIY66929.1 - 2e-58 195.9 0.5 3.1e-31 108.3 0.0 2.7 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.9 KIY66929.1 - 3.2e-41 141.1 0.7 5.4e-41 140.4 0.7 1.3 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.6 KIY66929.1 - 1.8e-18 65.9 0.0 5.5e-18 64.3 0.0 1.9 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Amidohydro_2 PF04909.14 KIY66929.1 - 0.028 14.2 0.0 0.075 12.8 0.0 1.7 1 0 0 1 1 1 0 Amidohydrolase MR_MLE_C PF13378.6 KIY66930.1 - 4.2e-47 160.5 0.4 4.3e-46 157.2 0.4 2.1 1 1 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KIY66930.1 - 3.4e-07 30.5 0.0 7.9e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.11 KIY66930.1 - 0.0046 16.1 0.0 0.0075 15.4 0.0 1.3 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus Peptidase_C25_C PF03785.14 KIY66930.1 - 0.012 15.5 0.1 0.021 14.7 0.1 1.4 1 0 0 1 1 1 0 Peptidase family C25, C terminal ig-like domain ADH_zinc_N PF00107.26 KIY66931.1 - 1.3e-21 76.9 0.1 2.4e-21 76.1 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KIY66931.1 - 8.1e-18 64.3 0.0 1.9e-17 63.1 0.0 1.7 2 0 0 2 2 2 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 KIY66931.1 - 3.8e-05 24.7 0.0 0.00012 23.1 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Cons_hypoth698 PF03601.14 KIY66932.1 - 0.049 12.5 0.4 0.049 12.5 0.4 2.4 1 1 1 2 2 2 0 Conserved hypothetical protein 698 Sugar_tr PF00083.24 KIY66933.1 - 2.8e-89 300.1 13.8 3.5e-89 299.8 13.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY66933.1 - 1.3e-24 86.8 21.4 1.8e-24 86.4 21.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DMT_6 PF04342.12 KIY66933.1 - 0.054 13.7 0.9 0.73 10.1 0.0 2.6 2 1 0 2 2 2 0 Putative member of DMT superfamily (DUF486) CSTF2_hinge PF14327.6 KIY66935.1 - 1.2e-24 86.5 0.3 2.8e-24 85.3 0.3 1.6 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 KIY66935.1 - 1.8e-22 78.9 0.0 2.9e-22 78.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 KIY66935.1 - 6.5e-12 44.8 1.8 1.4e-11 43.8 1.8 1.5 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal RRM_7 PF16367.5 KIY66935.1 - 0.011 15.8 0.0 0.028 14.5 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif SPATA3 PF15662.5 KIY66935.1 - 0.45 11.1 10.2 0.7 10.5 10.2 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated protein 3 family TFIIA PF03153.13 KIY66935.1 - 8.8 6.2 9.0 11 5.9 9.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4470 PF14737.6 KIY66936.1 - 3.4e-26 91.3 0.3 7.5e-26 90.2 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.18 KIY66936.1 - 1.4e-08 34.6 14.3 3e-08 33.6 14.3 1.5 1 0 0 1 1 1 1 MYND finger zf-C2H2_jaz PF12171.8 KIY66938.1 - 0.0017 18.6 4.1 0.01 16.1 0.1 3.1 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KIY66938.1 - 0.0022 18.7 25.5 0.066 14.1 1.3 4.4 4 1 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.26 KIY66938.1 - 0.0025 18.2 28.3 0.008 16.6 1.2 4.2 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-met PF12874.7 KIY66938.1 - 0.0025 18.2 5.0 0.53 10.8 0.2 3.3 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 KIY66938.1 - 0.33 11.3 7.0 0.16 12.3 4.4 1.8 2 0 0 2 2 2 0 C2H2-type zinc ribbon SKN1 PF03935.15 KIY66939.1 - 3e-182 606.5 7.1 7.8e-181 601.8 7.1 2.0 1 1 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Glyco_hydro_16 PF00722.21 KIY66939.1 - 0.00014 21.4 0.0 0.12 11.9 0.0 2.4 2 0 0 2 2 2 2 Glycosyl hydrolases family 16 FAD_binding_4 PF01565.23 KIY66940.1 - 2.6e-17 62.9 0.1 5e-17 61.9 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KIY66940.1 - 7.3e-08 32.4 0.2 4.4e-07 29.9 0.1 2.3 2 0 0 2 2 2 1 Berberine and berberine like MSA-2c PF12238.8 KIY66942.1 - 0.36 10.8 2.1 0.46 10.5 2.1 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c TrkH PF02386.16 KIY66946.1 - 5.9e-93 312.0 9.8 3.5e-92 309.5 1.9 2.1 2 0 0 2 2 2 2 Cation transport protein Nro1 PF12753.7 KIY66949.1 - 0.12 11.3 0.6 8.6 5.2 0.0 2.2 2 0 0 2 2 2 0 Nuclear pore complex subunit Nro1 O-FucT PF10250.9 KIY66950.1 - 3.5e-11 43.4 0.0 6e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Baseplate_J PF04865.14 KIY66951.1 - 0.028 13.6 0.0 0.04 13.1 0.0 1.1 1 0 0 1 1 1 0 Baseplate J-like protein RNA_helicase PF00910.22 KIY66951.1 - 0.071 13.5 0.1 0.099 13.0 0.1 1.3 1 0 0 1 1 1 0 RNA helicase MFS_1 PF07690.16 KIY66952.1 - 2.9e-36 125.1 29.0 5.8e-36 124.1 29.3 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Epimerase PF01370.21 KIY66955.1 - 2e-10 40.6 0.0 3.5e-10 39.7 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KIY66955.1 - 0.052 12.9 0.1 0.17 11.3 0.0 1.9 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase MoeA_C PF03454.15 KIY66955.1 - 0.071 13.3 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 MoeA C-terminal region (domain IV) Mito_carr PF00153.27 KIY66956.1 - 4.3e-63 209.3 6.0 8.2e-22 76.9 0.3 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein V4R PF02830.18 KIY66956.1 - 0.16 12.0 0.4 0.46 10.5 0.0 2.0 2 0 0 2 2 2 0 V4R domain Tim17 PF02466.19 KIY66956.1 - 0.71 10.3 5.9 18 5.7 0.0 3.4 1 1 1 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family Endostatin PF06482.11 KIY66957.1 - 0.27 10.7 1.2 0.34 10.3 1.2 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Zip PF02535.22 KIY66957.1 - 0.85 8.8 5.2 1 8.5 5.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Peptidase_M35 PF02102.15 KIY66958.1 - 1.1e-31 110.0 17.9 1.5e-31 109.6 17.9 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 KIY66958.1 - 7.7e-22 78.4 6.3 1.5e-21 77.4 6.3 1.5 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase HRXXH PF13933.6 KIY66958.1 - 5.5e-06 26.1 5.6 1.1e-05 25.1 5.6 1.5 1 1 0 1 1 1 1 Putative peptidase family TrkA_C PF02080.21 KIY66958.1 - 0.11 12.3 0.1 16 5.4 0.1 2.4 2 0 0 2 2 2 0 TrkA-C domain p450 PF00067.22 KIY66959.1 - 4.1e-58 197.3 0.0 5.1e-58 196.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Amino_oxidase PF01593.24 KIY66960.1 - 1.7e-21 77.0 0.0 4.9e-20 72.2 0.0 2.3 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KIY66960.1 - 2.6e-14 53.2 0.0 1.9e-13 50.4 0.0 2.4 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KIY66960.1 - 3e-07 30.4 0.4 1.2e-05 25.1 0.4 2.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KIY66960.1 - 1.8e-06 28.1 0.0 0.0079 16.2 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KIY66960.1 - 0.0024 17.2 0.0 0.033 13.4 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIY66960.1 - 0.0093 16.5 0.1 0.098 13.2 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KIY66960.1 - 0.015 14.4 0.0 0.034 13.2 0.0 1.6 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 KIY66960.1 - 0.033 13.4 0.0 0.05 12.8 0.0 1.2 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 KIY66960.1 - 0.042 12.6 0.0 0.82 8.3 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Glyco_hydro_92 PF07971.12 KIY66961.1 - 3.9e-130 434.9 3.4 5e-130 434.5 3.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 KIY66961.1 - 4.8e-56 190.3 0.9 7.3e-56 189.7 0.9 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain NT-C2 PF10358.9 KIY66963.1 - 7.4e-18 64.7 0.1 1.2e-16 60.7 0.1 2.1 1 1 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins EFTUD2 PF16004.5 KIY66963.1 - 0.014 16.0 0.0 4.4 7.9 0.0 2.2 2 0 0 2 2 2 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus Rtt106 PF08512.12 KIY66964.1 - 9.8e-17 61.2 0.0 2.6e-16 59.8 0.0 1.7 2 0 0 2 2 2 1 Histone chaperone Rttp106-like PH_18 PF18469.1 KIY66964.1 - 0.2 11.7 0.1 0.36 10.8 0.1 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain Nop14 PF04147.12 KIY66964.1 - 4.4 5.4 15.4 7.9 4.5 15.4 1.4 1 0 0 1 1 1 0 Nop14-like family zf-C2H2 PF00096.26 KIY66965.1 - 8e-05 22.9 6.2 0.02 15.4 0.7 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIY66965.1 - 0.081 13.8 0.7 0.081 13.8 0.7 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KIY66965.1 - 0.31 11.4 7.5 0.29 11.4 2.0 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding O-FucT PF10250.9 KIY66967.1 - 2.1e-11 44.2 0.0 1.8e-10 41.1 0.0 2.0 2 0 0 2 2 2 1 GDP-fucose protein O-fucosyltransferase PIG-P PF08510.12 KIY66968.1 - 1.6e-33 115.2 1.1 1.9e-33 114.9 1.1 1.1 1 0 0 1 1 1 1 PIG-P DPM2 PF07297.12 KIY66968.1 - 0.93 9.8 9.3 2.4 8.5 9.2 1.7 1 1 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) ABC2_membrane_3 PF12698.7 KIY66968.1 - 5.8 5.9 7.9 7.3 5.6 7.9 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein F-box-like PF12937.7 KIY66971.1 - 4.6e-09 36.0 0.9 8.7e-09 35.1 0.9 1.5 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KIY66971.1 - 0.0018 18.1 1.8 0.36 10.8 0.4 2.2 2 0 0 2 2 2 2 F-box domain F-box-like_2 PF13013.6 KIY66971.1 - 0.042 13.8 0.3 0.11 12.5 0.3 1.7 1 1 0 1 1 1 0 F-box-like domain FCD PF07729.12 KIY66973.1 - 0.045 14.2 0.1 0.079 13.4 0.1 1.4 1 0 0 1 1 1 0 FCD domain LRR_2 PF07723.13 KIY66974.1 - 0.065 13.9 1.4 2 9.2 0.1 2.8 2 0 0 2 2 2 0 Leucine Rich Repeat zf-Di19 PF05605.12 KIY66975.1 - 0.18 12.1 0.2 0.18 12.1 0.2 1.7 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.26 KIY66975.1 - 1.7 9.3 4.6 14 6.4 0.2 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF4470 PF14737.6 KIY66977.1 - 7.1e-22 77.4 0.0 1.3e-21 76.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.18 KIY66977.1 - 6.1e-10 39.0 12.4 1.2e-09 38.1 12.4 1.5 1 0 0 1 1 1 1 MYND finger Utp12 PF04003.12 KIY66977.1 - 0.16 12.3 0.0 0.33 11.3 0.0 1.5 1 0 0 1 1 1 0 Dip2/Utp12 Family zf-HIT PF04438.16 KIY66977.1 - 1.5 8.7 6.3 2.6 8.0 6.3 1.4 1 0 0 1 1 1 0 HIT zinc finger p450 PF00067.22 KIY66978.1 - 1.5e-76 258.0 0.0 1.9e-76 257.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Laminin_II PF06009.12 KIY66981.1 - 0.022 14.7 5.3 0.097 12.7 0.2 3.3 3 0 0 3 3 3 0 Laminin Domain II NPV_P10 PF05531.12 KIY66981.1 - 1.8 9.1 13.0 0.94 10.0 0.4 4.6 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.12 KIY66981.1 - 5 7.2 6.9 41 4.2 0.4 3.9 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF5610 PF18433.1 KIY66981.1 - 8.9 6.9 7.7 0.94 10.0 1.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF5610) Beta_helix PF13229.6 KIY66982.1 - 4.7e-08 33.0 15.2 4.8e-06 26.5 6.9 2.5 2 1 1 3 3 3 2 Right handed beta helix region Chondroitinas_B PF14592.6 KIY66982.1 - 2.2e-07 30.1 0.0 6.1e-07 28.7 0.0 1.7 2 0 0 2 2 2 1 Chondroitinase B DUF1565 PF07602.11 KIY66982.1 - 0.014 14.8 0.4 0.014 14.8 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1565) FA_hydroxylase PF04116.13 KIY66983.1 - 8.8e-25 87.6 19.3 8.8e-25 87.6 19.3 1.8 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily zf-C2H2 PF00096.26 KIY66984.1 - 1.2e-05 25.5 19.5 0.0099 16.3 0.8 3.3 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIY66984.1 - 3.3e-05 24.4 19.1 0.35 11.8 0.4 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger FOXP-CC PF16159.5 KIY66984.1 - 0.00026 21.5 13.4 0.015 15.9 0.9 3.2 1 1 2 3 3 3 2 FOXP coiled-coil domain zf-H2C2_2 PF13465.6 KIY66984.1 - 0.0015 18.9 2.7 0.0015 18.9 2.7 3.6 4 0 0 4 4 4 1 Zinc-finger double domain zf-H2C2_5 PF13909.6 KIY66984.1 - 0.0016 18.1 16.0 0.01 15.6 0.4 2.5 2 0 0 2 2 2 2 C2H2-type zinc-finger domain KdpC PF02669.15 KIY66984.1 - 0.0045 16.8 0.1 0.0067 16.3 0.1 1.2 1 0 0 1 1 1 1 K+-transporting ATPase, c chain zf-Di19 PF05605.12 KIY66984.1 - 0.015 15.6 12.3 0.22 11.9 1.6 2.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-met2 PF12907.7 KIY66984.1 - 0.024 14.8 1.9 0.024 14.8 1.9 3.3 3 0 0 3 3 3 0 Zinc-binding zf-BED PF02892.15 KIY66984.1 - 0.9 9.6 12.0 3.8 7.6 0.9 2.5 2 0 0 2 2 2 0 BED zinc finger zf-C2H2_2 PF12756.7 KIY66984.1 - 8 6.9 10.4 7.4 7.0 1.6 2.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Fungal_trans PF04082.18 KIY66985.1 - 8.1e-24 84.1 0.0 4.3e-23 81.7 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY66985.1 - 7.3e-08 32.4 11.4 1.3e-07 31.6 11.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box-like PF12937.7 KIY66987.1 - 2.2e-07 30.7 0.9 2.2e-07 30.7 0.9 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIY66987.1 - 5.5e-05 22.9 0.0 0.00031 20.5 0.0 2.3 1 1 1 2 2 2 1 F-box domain F-box-like PF12937.7 KIY66988.1 - 7.1e-08 32.2 1.6 2.3e-07 30.6 1.6 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY66988.1 - 0.0015 18.4 1.7 0.0032 17.3 0.2 2.5 2 1 0 2 2 2 1 F-box domain F-box-like PF12937.7 KIY66990.1 - 2.7e-08 33.6 1.0 5.3e-08 32.6 1.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY66990.1 - 5.6e-06 26.1 0.6 1.3e-05 24.9 0.6 1.6 1 0 0 1 1 1 1 F-box domain DUF5082 PF16888.5 KIY66990.1 - 0.0087 16.3 0.2 0.012 15.9 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF5082) Prefoldin PF02996.17 KIY66990.1 - 0.016 15.1 0.1 0.024 14.6 0.1 1.2 1 0 0 1 1 1 0 Prefoldin subunit DASH_Spc19 PF08287.11 KIY66990.1 - 0.021 14.7 0.7 0.029 14.3 0.7 1.1 1 0 0 1 1 1 0 Spc19 CorA PF01544.18 KIY66990.1 - 0.025 13.9 0.1 0.027 13.8 0.1 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Prefoldin_2 PF01920.20 KIY66990.1 - 0.049 13.6 0.0 0.067 13.1 0.0 1.2 1 0 0 1 1 1 0 Prefoldin subunit Cep57_MT_bd PF06657.13 KIY66990.1 - 0.059 13.8 0.0 0.1 13.0 0.0 1.3 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 TRAF_BIRC3_bd PF16673.5 KIY66990.1 - 0.06 13.1 0.0 0.095 12.5 0.0 1.3 1 0 0 1 1 1 0 TNF receptor-associated factor BIRC3 binding domain F-box-like_2 PF13013.6 KIY66990.1 - 0.084 12.9 0.1 0.16 12.0 0.1 1.7 1 1 0 1 1 1 0 F-box-like domain BAR_3 PF16746.5 KIY66990.1 - 0.11 12.1 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 BAR domain of APPL family GOLGA2L5 PF15070.6 KIY66990.1 - 0.16 10.6 0.0 0.18 10.4 0.0 1.0 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 DASH_Dam1 PF08653.10 KIY66990.1 - 0.17 11.7 0.1 0.25 11.2 0.1 1.3 1 0 0 1 1 1 0 DASH complex subunit Dam1 F-box-like PF12937.7 KIY66991.1 - 1.4e-06 28.1 0.8 1.4e-06 28.1 0.8 2.3 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 KIY66991.1 - 0.0051 16.7 0.1 0.012 15.5 0.1 1.6 1 0 0 1 1 1 1 F-box domain Agglutinin PF07468.11 KIY66991.1 - 0.11 12.7 0.0 0.18 12.0 0.0 1.2 1 0 0 1 1 1 0 Agglutinin domain BK_channel_a PF03493.18 KIY66991.1 - 0.17 12.1 0.0 0.31 11.2 0.0 1.3 1 0 0 1 1 1 0 Calcium-activated BK potassium channel alpha subunit LRR_6 PF13516.6 KIY66992.1 - 6.3e-13 47.7 23.4 0.00073 19.4 0.0 9.4 10 0 0 10 10 10 5 Leucine Rich repeat LRR_1 PF00560.33 KIY66992.1 - 8.2e-07 28.7 3.9 15 6.6 0.0 7.0 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_4 PF12799.7 KIY66992.1 - 3.6e-06 27.2 21.6 0.0057 17.1 1.0 5.4 4 1 2 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KIY66992.1 - 0.0027 17.4 21.7 2.6 7.9 6.2 6.6 3 1 4 7 7 7 4 Leucine rich repeat RCC1 PF00415.18 KIY66994.1 - 1.7e-55 185.4 6.4 5.5e-11 42.9 0.1 8.0 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KIY66994.1 - 2.1e-29 100.6 27.2 1.9e-07 30.7 0.2 7.1 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat SUKH-3 PF14433.6 KIY66994.1 - 0.00082 19.9 0.8 21 5.6 0.0 4.4 2 1 3 5 5 5 2 SUKH-3 immunity protein Pkinase_fungal PF17667.1 KIY66996.1 - 2.1e-19 69.6 0.0 7.6e-19 67.8 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Pkinase PF00069.25 KIY66996.1 - 0.00038 19.9 0.0 0.0006 19.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain RRN9 PF10680.9 KIY66996.1 - 0.14 12.5 0.4 0.33 11.3 0.4 1.7 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor Pkinase_fungal PF17667.1 KIY66997.1 - 1e-17 64.0 0.0 1.4e-17 63.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KIY66997.1 - 0.0085 16.0 0.0 0.012 15.5 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KIY66997.1 - 0.0091 15.6 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KIY66997.1 - 0.032 13.6 0.0 0.055 12.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family EcKinase PF02958.20 KIY66997.1 - 0.18 11.1 0.0 0.29 10.4 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase RRM_1 PF00076.22 KIY66998.1 - 2.3e-06 27.3 0.0 5.9e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 KIY66999.1 - 4.9e-23 80.7 0.0 8.4e-11 41.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KIY66999.1 - 0.00012 22.1 0.1 0.76 9.9 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif RRM_3 PF08777.11 KIY66999.1 - 0.00021 21.3 0.0 0.27 11.3 0.0 2.3 2 0 0 2 2 2 2 RNA binding motif Ion_trans PF00520.31 KIY67001.1 - 9.8e-120 398.3 94.7 3.5e-38 131.2 7.1 5.1 5 0 0 5 5 5 5 Ion transport protein PKD_channel PF08016.12 KIY67001.1 - 0.00072 18.3 11.3 0.00072 18.3 11.3 7.5 6 2 1 7 7 7 4 Polycystin cation channel DC_STAMP PF07782.13 KIY67003.1 - 1.4 8.7 5.5 0.46 10.3 2.2 1.8 2 0 0 2 2 2 0 DC-STAMP-like protein DUF951 PF06107.11 KIY67004.1 - 0.027 14.4 0.8 3.4 7.6 0.1 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF951) E6 PF00518.17 KIY67004.1 - 0.11 12.9 0.9 1.8 9.0 0.1 2.3 1 1 1 2 2 2 0 Early Protein (E6) COX7C PF02935.16 KIY67006.1 - 2.7e-08 33.9 2.7 3.2e-08 33.7 2.7 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc Polysacc_synt_4 PF04669.13 KIY67008.1 - 1.8e-17 63.6 0.2 3e-15 56.3 0.2 2.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis DivIC PF04977.15 KIY67008.1 - 0.074 12.8 7.5 0.14 11.9 7.5 1.5 1 0 0 1 1 1 0 Septum formation initiator Presenilin PF01080.17 KIY67008.1 - 1.6 7.4 2.8 1.7 7.3 2.8 1.2 1 0 0 1 1 1 0 Presenilin F-box-like PF12937.7 KIY67009.1 - 1.6e-07 31.1 1.7 1.6e-07 31.1 1.7 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIY67009.1 - 7.1 6.6 9.9 2 8.4 2.9 3.2 3 1 0 3 3 3 0 F-box domain F-box-like PF12937.7 KIY67010.1 - 2.1e-08 33.9 4.9 5.9e-08 32.5 0.4 3.1 3 1 0 3 3 3 1 F-box-like F-box PF00646.33 KIY67010.1 - 0.039 13.8 1.4 0.53 10.2 0.5 2.9 2 0 0 2 2 2 0 F-box domain GMC_oxred_N PF00732.19 KIY67011.1 - 8.8e-57 192.7 0.0 1.1e-56 192.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIY67011.1 - 4.7e-30 105.0 0.0 8.8e-30 104.1 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_3 PF13738.6 KIY67011.1 - 7.5e-05 22.1 0.0 0.0026 17.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIY67011.1 - 0.0017 18.6 0.6 0.0051 17.0 0.6 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KIY67011.1 - 0.0035 16.5 0.6 0.0053 15.9 0.6 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KIY67011.1 - 0.014 14.5 1.3 0.028 13.5 1.3 1.5 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.14 KIY67011.1 - 0.032 13.5 0.1 0.088 12.0 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KIY67011.1 - 0.039 12.6 0.1 0.071 11.8 0.1 1.4 1 0 0 1 1 1 0 HI0933-like protein DAO PF01266.24 KIY67011.1 - 0.043 13.4 3.4 0.073 12.6 0.6 2.4 3 0 0 3 3 3 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KIY67011.1 - 0.14 11.4 0.3 0.25 10.6 0.3 1.3 1 0 0 1 1 1 0 FAD binding domain F-box-like PF12937.7 KIY67012.1 - 5.2e-07 29.5 0.1 5.2e-07 29.5 0.1 2.7 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 KIY67012.1 - 0.27 11.2 3.2 0.61 10.0 0.3 2.8 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.7 KIY67013.1 - 8.2e-08 32.0 1.9 8.2e-08 32.0 1.9 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIY67013.1 - 0.75 9.7 7.8 0.37 10.7 3.3 2.7 2 1 0 2 2 2 0 F-box domain F-box-like PF12937.7 KIY67014.1 - 2.5e-06 27.3 0.4 7.4e-06 25.8 0.4 1.9 1 0 0 1 1 1 1 F-box-like Methyltransf_2 PF00891.18 KIY67016.1 - 1.2e-18 67.2 0.0 1.3e-15 57.2 0.0 2.1 2 0 0 2 2 2 2 O-methyltransferase domain RNA_pol_Rpc34 PF05158.12 KIY67016.1 - 0.0021 17.5 0.0 0.0033 16.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit tify PF06200.14 KIY67016.1 - 0.049 13.0 0.0 0.11 11.8 0.0 1.6 1 0 0 1 1 1 0 tify domain RPA_C PF08784.11 KIY67016.1 - 0.087 13.5 0.0 0.18 12.4 0.0 1.5 1 0 0 1 1 1 0 Replication protein A C terminal Dimerisation PF08100.11 KIY67016.1 - 0.15 12.1 0.0 0.47 10.5 0.0 1.9 1 0 0 1 1 1 0 Dimerisation domain Sulfate_transp PF00916.20 KIY67017.1 - 2e-57 194.7 16.6 2e-57 194.7 16.6 1.5 2 0 0 2 2 2 1 Sulfate permease family cNMP_binding PF00027.29 KIY67017.1 - 2.4e-13 50.0 0.0 5e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.21 KIY67017.1 - 8.1e-12 44.8 0.0 1.6e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 KIY67017.1 - 0.037 14.4 0.0 0.093 13.1 0.0 1.6 1 0 0 1 1 1 0 STAS domain TPR_1 PF00515.28 KIY67018.1 - 5.3e-32 108.3 18.0 0.001 18.8 0.0 11.0 10 1 0 10 10 10 7 Tetratricopeptide repeat TPR_2 PF07719.17 KIY67018.1 - 8.4e-30 100.5 25.6 0.002 18.1 0.5 11.2 12 0 0 12 12 12 7 Tetratricopeptide repeat TPR_8 PF13181.6 KIY67018.1 - 3.2e-20 70.6 11.1 0.0011 19.0 0.1 9.8 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_16 PF13432.6 KIY67018.1 - 9.8e-19 67.7 17.7 4.9e-05 23.9 0.0 6.1 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_12 PF13424.6 KIY67018.1 - 1.3e-15 57.4 13.4 0.047 14.0 0.1 7.4 5 2 3 8 8 8 6 Tetratricopeptide repeat TPR_17 PF13431.6 KIY67018.1 - 2.3e-15 55.7 7.0 0.044 14.2 0.4 7.8 7 1 1 8 8 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 KIY67018.1 - 3.3e-15 55.5 17.3 0.0023 18.6 0.0 8.4 7 2 2 9 9 8 3 Tetratricopeptide repeat TPR_19 PF14559.6 KIY67018.1 - 6.2e-15 55.5 16.5 0.00028 21.3 0.7 6.3 4 1 1 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 KIY67018.1 - 2.9e-12 45.7 4.9 0.017 15.1 0.0 6.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 KIY67018.1 - 1.8e-10 40.3 13.5 0.00045 19.8 0.0 8.0 6 2 3 9 9 9 3 TPR repeat TPR_9 PF13371.6 KIY67018.1 - 2.6e-10 40.3 6.7 0.072 13.2 0.0 5.9 5 2 0 6 6 6 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KIY67018.1 - 1.5e-07 31.5 8.2 0.63 10.3 0.0 5.0 3 1 2 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 KIY67018.1 - 6.1e-05 22.6 6.9 8.4e-05 22.1 0.8 3.0 2 1 0 3 3 3 1 MalT-like TPR region TPR_10 PF13374.6 KIY67018.1 - 0.0047 16.8 18.3 1.4 8.9 0.1 7.4 8 0 0 8 8 8 1 Tetratricopeptide repeat CSTF_C PF14304.6 KIY67018.1 - 0.0075 15.8 0.1 0.016 14.7 0.1 1.6 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal DUF3856 PF12968.7 KIY67018.1 - 0.014 15.5 3.3 0.88 9.6 0.1 4.1 3 2 1 4 4 4 0 Domain of Unknown Function (DUF3856) BTAD PF03704.17 KIY67018.1 - 0.067 13.6 8.4 20 5.6 0.1 3.8 3 1 1 4 4 4 0 Bacterial transcriptional activator domain HrpB1_HrpK PF09613.10 KIY67018.1 - 0.07 12.8 0.0 4.6 6.9 0.0 2.6 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_6 PF13174.6 KIY67018.1 - 0.081 13.6 14.8 40 5.1 0.0 7.0 8 1 0 8 8 6 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 KIY67018.1 - 0.22 11.5 2.9 2.7 8.1 0.1 3.5 4 0 0 4 4 3 0 Putative TPR-like repeat DUF4810 PF16068.5 KIY67018.1 - 0.23 12.0 1.8 14 6.3 0.1 4.0 3 1 1 4 4 4 0 Domain of unknown function (DUF4810) TPR_20 PF14561.6 KIY67018.1 - 1.9 8.9 13.2 9.2 6.7 0.6 5.2 4 1 1 5 5 5 0 Tetratricopeptide repeat Methyltransf_2 PF00891.18 KIY67020.1 - 1e-13 51.1 0.0 2.4e-13 49.9 0.0 1.7 1 1 0 1 1 1 1 O-methyltransferase domain RNA_pol_Rpc34 PF05158.12 KIY67020.1 - 0.0036 16.7 0.0 0.0054 16.1 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit HTH_IclR PF09339.10 KIY67020.1 - 0.0079 16.0 0.2 0.19 11.5 0.0 2.9 3 0 0 3 3 3 1 IclR helix-turn-helix domain RPA_C PF08784.11 KIY67020.1 - 0.0096 16.6 0.0 0.024 15.3 0.0 1.6 1 0 0 1 1 1 1 Replication protein A C terminal DprA_WH PF17782.1 KIY67020.1 - 0.087 13.0 0.1 0.21 11.7 0.1 1.6 1 0 0 1 1 1 0 DprA winged helix domain NSs PF11073.8 KIY67020.1 - 0.096 12.1 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Rift valley fever virus non structural protein (NSs) like Methyltransf_2 PF00891.18 KIY67021.1 - 1.1e-15 57.5 0.0 2.4e-15 56.4 0.0 1.6 1 1 0 1 1 1 1 O-methyltransferase domain RPA_C PF08784.11 KIY67021.1 - 0.0062 17.2 0.0 0.021 15.5 0.0 1.8 2 0 0 2 2 2 1 Replication protein A C terminal DprA_WH PF17782.1 KIY67021.1 - 0.096 12.8 0.3 0.47 10.6 0.1 2.2 2 0 0 2 2 2 0 DprA winged helix domain NUDIX_2 PF13869.6 KIY67022.1 - 2.3e-84 281.7 0.0 2.6e-84 281.5 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase Tetraspanin PF00335.20 KIY67023.1 - 0.0018 18.0 4.4 0.0018 18.0 4.4 3.0 4 0 0 4 4 4 1 Tetraspanin family AMP-binding PF00501.28 KIY67026.1 - 7.4e-37 126.9 0.0 2.8e-36 125.1 0.0 1.7 2 0 0 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.12 KIY67026.1 - 1e-17 64.2 0.0 1.8e-17 63.4 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 KIY67026.1 - 3.7e-08 33.1 0.0 6.1e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KIY67026.1 - 1.8e-05 25.0 0.0 4.3e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site CcmH PF03918.14 KIY67028.1 - 0.043 13.1 0.0 0.065 12.5 0.0 1.3 1 0 0 1 1 1 0 Cytochrome C biogenesis protein DUF2207 PF09972.9 KIY67028.1 - 0.045 12.5 0.1 0.046 12.5 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) FA_desaturase PF00487.24 KIY67028.1 - 0.045 13.6 0.2 0.052 13.4 0.2 1.2 1 0 0 1 1 1 0 Fatty acid desaturase EbsA PF17255.2 KIY67028.1 - 0.2 12.0 2.4 0.33 11.3 2.4 1.3 1 0 0 1 1 1 0 EbsA-like protein F-box-like PF12937.7 KIY67029.1 - 3.9e-05 23.5 2.4 0.00013 21.8 0.2 2.8 2 1 0 2 2 2 1 F-box-like F-box PF00646.33 KIY67029.1 - 0.013 15.4 0.3 0.013 15.4 0.3 2.7 2 1 0 2 2 2 0 F-box domain F-box-like PF12937.7 KIY67030.1 - 1e-05 25.3 0.1 3.6e-05 23.6 0.1 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY67030.1 - 0.008 16.0 1.0 0.021 14.7 0.4 2.1 2 1 0 2 2 2 1 F-box domain Xan_ur_permease PF00860.20 KIY67031.1 - 4.3e-27 94.8 27.3 4e-17 62.0 8.9 2.5 2 1 0 2 2 2 2 Permease family Sulfate_transp PF00916.20 KIY67031.1 - 0.0007 18.4 14.8 0.0007 18.4 14.8 2.5 1 1 1 2 2 2 1 Sulfate permease family MFS_MOT1 PF16983.5 KIY67031.1 - 0.02 15.3 5.7 0.02 15.3 5.7 2.8 2 0 0 2 2 2 0 Molybdate transporter of MFS superfamily F-box-like PF12937.7 KIY67032.1 - 1.6e-07 31.1 0.1 8.7e-07 28.7 0.0 2.4 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 KIY67033.1 - 1.3e-06 28.2 0.6 4e-06 26.6 0.2 2.2 2 0 0 2 2 2 1 F-box-like Peptidase_M43 PF05572.13 KIY67034.1 - 3.7e-16 59.4 0.2 5.7e-16 58.8 0.2 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 KIY67034.1 - 0.0026 18.0 1.6 0.0026 18.0 1.6 1.7 2 1 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 KIY67034.1 - 0.0048 17.4 0.1 0.0095 16.4 0.1 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M7 PF02031.16 KIY67034.1 - 0.0085 16.2 0.6 0.019 15.1 0.6 1.7 1 1 0 1 1 1 1 Streptomyces extracellular neutral proteinase (M7) family Peptidase_M66 PF10462.9 KIY67034.1 - 0.019 13.9 0.5 0.028 13.4 0.5 1.2 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M10 PF00413.24 KIY67034.1 - 0.022 14.6 0.0 0.029 14.2 0.0 1.3 1 0 0 1 1 1 0 Matrixin Reprolysin_4 PF13583.6 KIY67034.1 - 0.085 12.5 0.1 0.15 11.7 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like AhpC-TSA PF00578.21 KIY67035.1 - 2.1e-30 105.2 0.0 2.8e-30 104.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KIY67035.1 - 8.5e-11 41.8 0.0 1.8e-10 40.7 0.0 1.5 2 0 0 2 2 2 1 Redoxin 1-cysPrx_C PF10417.9 KIY67035.1 - 9.2e-10 38.2 0.1 1.8e-09 37.3 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin RhoGEF PF00621.20 KIY67037.1 - 1.8e-10 41.4 0.0 2.9e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain Transposase_21 PF02992.14 KIY67041.1 - 0.00015 21.1 0.0 0.00019 20.7 0.0 1.2 1 0 0 1 1 1 1 Transposase family tnp2 Ribonuc_2-5A PF06479.12 KIY67044.1 - 2.5e-45 153.7 0.3 4.4e-45 152.9 0.3 1.4 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.25 KIY67044.1 - 4.6e-39 134.4 0.0 4.1e-30 105.0 0.0 2.6 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIY67044.1 - 3.2e-20 72.5 0.0 2.6e-17 63.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase PQQ PF01011.21 KIY67044.1 - 0.0021 17.9 0.0 0.016 15.1 0.0 2.3 2 0 0 2 2 2 1 PQQ enzyme repeat APH PF01636.23 KIY67044.1 - 0.034 14.1 0.0 0.079 12.9 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KIY67044.1 - 0.035 12.9 0.0 0.11 11.3 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase PQQ_2 PF13360.6 KIY67044.1 - 0.098 12.2 0.0 0.4 10.2 0.0 2.0 1 1 0 1 1 1 0 PQQ-like domain Kdo PF06293.14 KIY67044.1 - 0.14 11.5 0.1 0.39 10.0 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-H2C2_2 PF13465.6 KIY67045.1 - 0.00023 21.5 0.6 0.00023 21.5 0.6 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.26 KIY67045.1 - 0.081 13.4 20.7 0.088 13.3 0.0 4.5 4 1 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIY67045.1 - 9.3 7.4 19.0 1.5 9.9 0.6 3.9 5 0 0 5 5 5 0 C2H2-type zinc finger Lactamase_B PF00753.27 KIY67047.1 - 2.1e-12 47.4 0.2 3.5e-12 46.7 0.2 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KIY67047.1 - 8.4e-05 22.2 0.3 0.00023 20.7 0.1 1.9 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Glyco_hydro_76 PF03663.14 KIY67050.1 - 1.3e-30 107.2 20.7 2.3e-30 106.4 20.7 1.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 KIY67050.1 - 0.0033 16.6 7.5 0.0051 15.9 0.2 2.6 2 1 1 3 3 3 2 Glycosyl Hydrolase Family 88 GYF_2 PF14237.6 KIY67050.1 - 0.028 14.2 0.0 0.38 10.6 0.0 2.4 2 0 0 2 2 2 0 GYF domain 2 Abhydrolase_3 PF07859.13 KIY67051.1 - 7e-12 45.7 0.0 2.4e-11 43.9 0.0 1.9 3 0 0 3 3 3 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KIY67051.1 - 1.5e-06 27.3 0.0 2.5e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Steryl acetyl hydrolase zf-C2H2_12 PF18658.1 KIY67052.1 - 0.072 12.7 0.1 0.2 11.2 0.1 1.7 1 0 0 1 1 1 0 Zinc-finger C2H2-type VEG PF06257.11 KIY67052.1 - 0.15 12.1 0.2 0.3 11.2 0.2 1.5 1 0 0 1 1 1 0 Biofilm formation stimulator VEG DNA_RNApol_7kD PF03604.13 KIY67052.1 - 0.5 10.1 3.6 1.9 8.2 0.0 2.7 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit DUF5127 PF17168.4 KIY67053.1 - 7.1e-60 202.6 0.7 7.1e-60 202.6 0.7 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 KIY67053.1 - 1.2e-40 138.9 0.6 3.2e-40 137.6 0.6 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 KIY67053.1 - 1.8e-34 119.6 3.3 4.5e-34 118.3 3.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) Bac_rhamnosid6H PF17389.2 KIY67053.1 - 0.0026 17.1 2.6 0.88 8.8 0.1 2.7 3 0 0 3 3 3 2 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Tetraspanin PF00335.20 KIY67054.1 - 3.4e-05 23.7 3.9 5.1e-05 23.1 3.9 1.3 1 1 0 1 1 1 1 Tetraspanin family SARAF PF06682.12 KIY67054.1 - 0.028 14.1 0.1 0.046 13.4 0.1 1.3 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DUF2417 PF10329.9 KIY67054.1 - 0.35 10.2 6.2 0.51 9.7 6.2 1.4 1 1 0 1 1 1 0 Region of unknown function (DUF2417) DUF2569 PF10754.9 KIY67054.1 - 1.1 9.7 7.7 0.23 11.9 4.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2569) DUF3754 PF12576.8 KIY67054.1 - 5.8 6.9 5.1 56 3.7 4.7 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3754) zf-C2H2 PF00096.26 KIY67055.1 - 4.3e-13 48.9 22.0 0.00076 19.8 0.1 5.6 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KIY67055.1 - 6.4e-09 35.9 27.0 0.0092 16.4 0.4 5.4 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 KIY67055.1 - 5.1e-08 33.1 20.3 0.009 16.8 0.1 5.4 5 0 0 5 5 5 4 C2H2-type zinc finger OrsD PF12013.8 KIY67055.1 - 0.018 15.5 19.8 9 6.8 0.0 5.9 5 2 1 6 6 6 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_3rep PF18868.1 KIY67055.1 - 0.088 13.5 1.5 0.14 12.8 0.1 2.1 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-H2C2_5 PF13909.6 KIY67055.1 - 0.16 11.7 23.9 6.6 6.6 0.3 6.1 6 0 0 6 6 6 0 C2H2-type zinc-finger domain FOXP-CC PF16159.5 KIY67055.1 - 3.1 8.5 9.7 79 4.0 0.2 4.4 2 2 2 4 4 4 0 FOXP coiled-coil domain zf-H2C2_2 PF13465.6 KIY67056.1 - 0.0052 17.2 2.6 0.066 13.7 0.0 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KIY67056.1 - 1.4 10.0 10.4 29 5.9 0.2 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger MFS_1 PF07690.16 KIY67057.1 - 8.8e-26 90.7 22.9 1.4e-25 90.0 22.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF5127 PF17168.4 KIY67059.1 - 2.6e-63 213.8 1.5 2.6e-63 213.8 1.5 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 KIY67059.1 - 5.3e-39 133.6 1.4 1.4e-38 132.3 1.4 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 KIY67059.1 - 4.8e-36 124.7 4.0 1.2e-35 123.5 4.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) Bac_rhamnosid6H PF17389.2 KIY67059.1 - 0.00058 19.2 1.6 0.019 14.3 1.5 2.3 1 1 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain SKG6 PF08693.10 KIY67059.1 - 0.076 12.4 0.0 0.18 11.3 0.0 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF2046 PF09755.9 KIY67059.1 - 0.24 10.6 0.2 0.35 10.1 0.2 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein H4 (DUF2046) PEP-CTERM PF07589.11 KIY67059.1 - 1.6 8.9 4.1 6.1 7.1 4.1 2.1 1 0 0 1 1 1 0 PEP-CTERM motif HNH_2 PF13391.6 KIY67060.1 - 6.8e-09 35.7 0.0 2e-08 34.2 0.0 1.9 1 0 0 1 1 1 1 HNH endonuclease SET PF00856.28 KIY67062.1 - 3.1e-20 73.2 0.1 1.7e-19 70.8 0.1 1.9 1 1 0 1 1 1 1 SET domain N-SET PF11764.8 KIY67063.1 - 6.5e-05 23.1 0.0 6.5e-05 23.1 0.0 3.7 2 1 1 3 3 3 1 COMPASS (Complex proteins associated with Set1p) component N RRM_1 PF00076.22 KIY67063.1 - 0.0023 17.7 0.0 0.0047 16.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CDRT4 PF15213.6 KIY67063.1 - 0.79 10.3 0.0 0.79 10.3 0.0 3.5 2 1 1 3 3 3 0 CMT1A duplicated region transcript 4 protein DDHD PF02862.17 KIY67063.1 - 4.8 7.3 9.3 11 6.2 9.3 1.6 1 0 0 1 1 1 0 DDHD domain DUF202 PF02656.15 KIY67064.1 - 0.12 12.9 0.0 0.17 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF202) EphA2_TM PF14575.6 KIY67064.1 - 0.19 12.6 0.0 0.33 11.9 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.15 KIY67064.1 - 0.25 11.1 1.1 0.41 10.5 1.1 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 RCR PF12273.8 KIY67064.1 - 0.59 10.8 23.6 1.1 9.9 23.6 1.7 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red RNase_P_Rpp14 PF01900.19 KIY67065.1 - 0.058 13.6 0.0 0.075 13.3 0.0 1.3 1 0 0 1 1 1 0 Rpp14/Pop5 family Chal_sti_synt_C PF02797.15 KIY67065.1 - 0.093 12.7 0.0 0.1 12.6 0.0 1.1 1 0 0 1 1 1 0 Chalcone and stilbene synthases, C-terminal domain NmrA PF05368.13 KIY67066.1 - 5.6e-09 35.9 0.1 8.1e-09 35.4 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KIY67066.1 - 8.9e-09 35.5 0.8 1.5e-08 34.7 0.8 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KIY67066.1 - 1e-05 25.1 0.0 0.0073 15.8 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KIY67066.1 - 3.8e-05 22.8 0.0 5.7e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KIY67066.1 - 0.00019 20.7 0.0 0.00033 19.9 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Peptidase_M48_N PF16491.5 KIY67067.1 - 1.4e-60 204.3 4.9 1.4e-60 204.3 4.9 2.1 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 KIY67067.1 - 3.4e-33 115.1 0.2 2.3e-21 76.4 0.0 3.2 3 0 0 3 3 3 3 Peptidase family M48 zf-RING_2 PF13639.6 KIY67070.1 - 7.2e-05 23.0 4.8 7.2e-05 23.0 4.8 1.7 2 0 0 2 2 2 1 Ring finger domain SWIM PF04434.17 KIY67070.1 - 0.0032 17.1 0.3 0.0055 16.3 0.3 1.4 1 0 0 1 1 1 1 SWIM zinc finger PHD PF00628.29 KIY67070.1 - 0.012 15.5 6.5 0.019 14.8 6.5 1.4 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.8 KIY67070.1 - 0.042 14.0 5.8 0.053 13.7 4.6 1.7 2 0 0 2 2 2 0 FANCL C-terminal domain Prok-RING_1 PF14446.6 KIY67070.1 - 0.76 9.8 6.3 0.22 11.4 3.0 1.8 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-C3HC4_3 PF13920.6 KIY67070.1 - 3 7.8 5.5 13 5.8 5.5 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) C1_1 PF00130.22 KIY67070.1 - 7.5 6.5 7.1 1.7 8.6 3.3 1.8 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase PF00069.25 KIY67073.1 - 7.3e-06 25.5 0.0 1.9e-05 24.2 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KIY67073.1 - 0.0013 18.1 0.0 0.0023 17.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIY67073.1 - 0.0092 15.9 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KIY67073.1 - 0.027 13.7 0.1 0.28 10.4 0.0 2.4 3 0 0 3 3 3 0 Protein tyrosine kinase WaaY PF06176.11 KIY67073.1 - 0.14 11.7 0.0 0.81 9.3 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide core biosynthesis protein (WaaY) Polysacc_deac_1 PF01522.21 KIY67074.1 - 4.8e-31 107.2 0.0 1.6e-30 105.5 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide deacetylase F-box PF00646.33 KIY67076.1 - 0.036 13.9 0.2 0.059 13.3 0.2 1.3 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 KIY67076.1 - 0.053 13.4 0.6 0.081 12.8 0.6 1.3 1 0 0 1 1 1 0 F-box-like Cytochrom_B561 PF03188.16 KIY67078.1 - 3.3e-14 53.2 7.1 7.3e-14 52.1 7.1 1.6 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 CDH-cyt PF16010.5 KIY67078.1 - 4.9e-14 52.4 0.9 9.5e-14 51.5 0.9 1.4 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase DOMON PF03351.17 KIY67078.1 - 6.2e-09 36.1 0.2 1.2e-08 35.2 0.2 1.4 1 0 0 1 1 1 1 DOMON domain DUF2427 PF10348.9 KIY67078.1 - 0.0031 17.3 3.6 0.012 15.4 3.6 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2427) MerC PF03203.14 KIY67078.1 - 0.11 13.0 0.4 0.11 13.0 0.4 3.5 3 1 1 4 4 4 0 MerC mercury resistance protein p450 PF00067.22 KIY67079.1 - 3.7e-72 243.5 0.0 5.4e-72 243.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 TetR_C_30 PF17939.1 KIY67079.1 - 0.15 12.3 0.0 0.91 9.8 0.0 2.3 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Abhydrolase_3 PF07859.13 KIY67080.1 - 2.9e-47 161.3 0.2 9.2e-47 159.6 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KIY67080.1 - 6.2e-13 48.4 0.0 3.1e-12 46.0 0.0 1.9 1 1 0 1 1 1 1 Steryl acetyl hydrolase COesterase PF00135.28 KIY67080.1 - 3.7e-05 22.8 0.0 0.0024 16.8 0.0 2.2 2 0 0 2 2 2 2 Carboxylesterase family Peptidase_S9 PF00326.21 KIY67080.1 - 0.0074 15.8 0.0 0.019 14.4 0.0 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 KIY67080.1 - 0.0077 16.1 0.0 0.017 15.0 0.0 1.5 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase DUF1664 PF07889.12 KIY67083.1 - 0.0058 16.7 1.3 0.0076 16.3 1.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) Spc7 PF08317.11 KIY67083.1 - 0.0092 14.9 2.8 0.01 14.7 2.8 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein HALZ PF02183.18 KIY67083.1 - 0.018 15.3 2.8 0.22 11.8 0.2 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper Med4 PF10018.9 KIY67083.1 - 0.12 12.0 2.1 0.15 11.8 2.1 1.1 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 Wbp11 PF09429.10 KIY67083.1 - 0.36 11.3 3.4 0.51 10.8 3.1 1.5 1 1 0 1 1 1 0 WW domain binding protein 11 ZapB PF06005.12 KIY67083.1 - 1.2 9.7 11.1 7.8 7.0 11.1 2.1 1 1 0 1 1 1 0 Cell division protein ZapB YabA PF06156.13 KIY67083.1 - 2.8 8.6 6.1 16 6.2 6.2 1.9 1 1 1 2 2 2 0 Initiation control protein YabA AcetylCoA_hyd_C PF13336.6 KIY67085.1 - 0.12 12.3 0.1 0.21 11.5 0.1 1.3 1 0 0 1 1 1 0 Acetyl-CoA hydrolase/transferase C-terminal domain CoatB PF10389.9 KIY67085.1 - 1.1 9.2 6.5 1.4 8.8 0.2 3.1 3 0 0 3 3 3 0 Bacteriophage coat protein B DJ-1_PfpI PF01965.24 KIY67086.1 - 7.7e-15 55.1 0.0 1.1e-14 54.6 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family AMPKBI PF04739.15 KIY67087.1 - 1.6e-24 86.0 0.9 7.7e-24 83.8 0.9 2.1 1 1 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interaction domain AMPK1_CBM PF16561.5 KIY67087.1 - 1.5e-10 41.1 0.0 2.5e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase adh_short_C2 PF13561.6 KIY67088.1 - 3.6e-39 134.7 1.1 1.8e-38 132.4 1.1 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIY67088.1 - 8.3e-37 126.5 0.4 1.5e-36 125.7 0.4 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIY67088.1 - 2.2e-05 24.4 1.1 3.1e-05 23.9 0.1 1.8 2 0 0 2 2 2 1 KR domain 3HCDH_N PF02737.18 KIY67088.1 - 0.023 14.6 1.4 0.031 14.2 0.3 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AA_permease_2 PF13520.6 KIY67089.1 - 0.0031 16.4 3.3 0.0035 16.3 3.3 1.1 1 0 0 1 1 1 1 Amino acid permease Cytochrom_B_C PF00032.17 KIY67089.1 - 0.016 15.5 3.4 0.017 15.4 2.0 1.7 1 1 1 2 2 2 0 Cytochrome b(C-terminal)/b6/petD DUF3810 PF12725.7 KIY67089.1 - 0.035 13.5 0.6 0.045 13.1 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) ATP_synt_H PF05493.13 KIY67089.1 - 0.26 11.8 4.9 0.62 10.6 4.9 1.6 1 0 0 1 1 1 0 ATP synthase subunit H GWT1 PF06423.12 KIY67089.1 - 0.42 10.7 3.8 0.44 10.6 3.3 1.4 1 1 0 1 1 1 0 GWT1 Glyoxal_oxid_N PF07250.11 KIY67090.1 - 4.9e-35 120.9 0.0 5.2e-26 91.3 0.0 3.4 3 0 0 3 3 3 2 Glyoxal oxidase N-terminus DUF1929 PF09118.11 KIY67090.1 - 2.8e-24 85.2 0.0 5.8e-24 84.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.6 KIY67090.1 - 0.00053 20.0 0.1 1.4 9.0 0.1 3.3 2 0 0 2 2 2 2 Galactose oxidase, central domain F-box-like PF12937.7 KIY67091.1 - 0.012 15.5 1.3 0.018 14.9 0.1 1.9 2 0 0 2 2 2 0 F-box-like RP-C_C PF11800.8 KIY67093.1 - 0.3 11.2 4.3 0.45 10.6 4.3 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region SOG2 PF10428.9 KIY67093.1 - 0.35 10.0 17.8 0.46 9.6 17.8 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein MCM_bind PF09739.9 KIY67093.1 - 1 7.7 5.1 1.4 7.3 5.1 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor RHD3 PF05879.12 KIY67094.1 - 5.3e-244 811.8 2.4 1.2e-243 810.6 2.4 1.5 1 1 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.19 KIY67094.1 - 8.6e-07 28.5 0.2 1.7e-06 27.5 0.2 1.5 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.23 KIY67094.1 - 3e-06 27.3 0.0 7.8e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KIY67094.1 - 1.9e-05 24.8 0.8 3.6e-05 23.9 0.0 1.8 2 0 0 2 2 2 1 Dynamin family AAA_28 PF13521.6 KIY67094.1 - 0.0016 18.7 0.4 0.0063 16.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain TK PF00265.18 KIY67094.1 - 0.02 14.8 0.0 0.04 13.8 0.0 1.5 1 0 0 1 1 1 0 Thymidine kinase Roc PF08477.13 KIY67094.1 - 0.061 13.5 0.1 0.19 11.9 0.1 1.9 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KIY67094.1 - 0.12 12.0 0.1 0.26 10.8 0.1 1.5 1 0 0 1 1 1 0 Ras family ABC_tran PF00005.27 KIY67094.1 - 0.12 12.9 0.1 2.6 8.6 0.0 2.3 2 0 0 2 2 2 0 ABC transporter MFS_1 PF07690.16 KIY67095.1 - 3.4e-36 124.9 24.8 3.4e-36 124.9 24.8 1.4 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KIY67095.1 - 4.9e-10 39.3 3.5 4.9e-10 39.3 3.5 2.1 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB BCS1_N PF08740.11 KIY67095.1 - 0.097 12.6 0.2 0.19 11.7 0.2 1.4 1 0 0 1 1 1 0 BCS1 N terminal CrgA PF06781.12 KIY67095.1 - 8.5 6.5 6.7 19 5.4 1.3 2.9 2 0 0 2 2 2 0 Cell division protein CrgA Nkap_C PF06047.11 KIY67096.1 - 9.3e-41 138.1 3.0 9.3e-41 138.1 3.0 2.3 2 1 0 2 2 2 1 NF-kappa-B-activating protein C-terminal domain FAM60A PF15396.6 KIY67096.1 - 9.1 6.2 17.9 1.2 9.1 11.9 2.2 2 0 0 2 2 2 0 Protein Family FAM60A Glyco_hydro_18 PF00704.28 KIY67098.1 - 4.4e-08 33.2 0.7 1.4e-07 31.6 0.7 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Glutaredoxin PF00462.24 KIY67099.1 - 9.2e-08 32.2 0.1 5.4e-07 29.7 0.1 2.1 1 1 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.6 KIY67099.1 - 0.0017 18.7 0.0 0.0028 18.1 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain RNA_pol_3_Rpc31 PF11705.8 KIY67100.1 - 0.79 9.9 20.1 2.5 8.3 20.1 1.8 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Nop25 PF09805.9 KIY67100.1 - 0.91 10.0 15.8 1.7 9.1 15.8 1.5 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) CNDH2_C PF16858.5 KIY67100.1 - 1.2 9.0 10.7 2.7 7.8 10.7 1.6 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term DDHD PF02862.17 KIY67100.1 - 4.1 7.5 6.7 77 3.3 6.7 2.1 1 1 0 1 1 1 0 DDHD domain NOA36 PF06524.12 KIY67100.1 - 7.4 5.8 13.1 19 4.4 13.1 1.7 1 0 0 1 1 1 0 NOA36 protein Plavaka PF18759.1 KIY67102.1 - 1.5e-107 359.6 0.1 2.4e-107 358.9 0.1 1.3 1 0 0 1 1 1 1 Plavaka transposase DUF3752 PF12572.8 KIY67104.1 - 3.8e-37 128.2 11.4 3.8e-37 128.2 11.4 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3752) Acetyltransf_3 PF13302.7 KIY67105.1 - 3.7e-19 69.8 0.0 4.3e-19 69.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIY67105.1 - 1.2e-06 28.8 0.0 1.6e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 KIY67105.1 - 0.017 14.8 0.0 0.029 14.0 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain CheR_N PF03705.15 KIY67105.1 - 0.053 13.3 0.0 0.15 11.8 0.0 1.6 2 0 0 2 2 2 0 CheR methyltransferase, all-alpha domain FR47 PF08445.10 KIY67105.1 - 0.1 12.6 0.3 0.88 9.6 0.1 2.1 2 0 0 2 2 2 0 FR47-like protein Peptidase_M3 PF01432.20 KIY67106.1 - 1.8e-133 446.2 0.0 2.4e-133 445.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.6 KIY67106.1 - 0.036 13.7 0.3 0.063 12.9 0.3 1.3 1 0 0 1 1 1 0 Peptidase M50B-like Arf PF00025.21 KIY67107.1 - 2.6e-41 141.0 0.0 3.2e-41 140.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KIY67107.1 - 1.9e-18 66.6 0.0 2.2e-18 66.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIY67107.1 - 3.9e-14 52.9 0.0 5.4e-14 52.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KIY67107.1 - 2.3e-08 33.7 0.0 2.7e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KIY67107.1 - 5.4e-07 29.2 0.0 6.1e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KIY67107.1 - 1.3e-05 25.3 0.0 1.7e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 KIY67107.1 - 1.8e-05 24.1 0.6 0.00022 20.5 0.1 2.3 2 1 0 2 2 2 1 G-protein alpha subunit Dynamin_N PF00350.23 KIY67107.1 - 0.0031 17.6 0.1 0.42 10.7 0.2 2.2 1 1 1 2 2 2 1 Dynamin family ATP_bind_1 PF03029.17 KIY67107.1 - 0.0082 15.9 0.1 0.67 9.7 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 KIY67107.1 - 0.01 15.4 0.0 0.017 14.7 0.0 1.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain DUF4508 PF14969.6 KIY67107.1 - 0.091 13.0 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4508) UPF1_Zn_bind PF09416.10 KIY67107.1 - 0.1 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 RNA helicase (UPF2 interacting domain) zf-MYND PF01753.18 KIY67108.1 - 0.013 15.5 7.9 0.024 14.7 7.9 1.4 1 0 0 1 1 1 0 MYND finger zf-HIT PF04438.16 KIY67108.1 - 0.58 10.1 8.1 2.9 7.8 8.1 2.1 1 1 0 1 1 1 0 HIT zinc finger Myticin-prepro PF10690.9 KIY67108.1 - 4.1 7.7 7.2 13 6.1 3.0 2.4 2 0 0 2 2 2 0 Myticin pre-proprotein from the mussel Sugar_tr PF00083.24 KIY67110.1 - 1.1e-86 291.6 21.9 1.2e-86 291.4 21.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY67110.1 - 1.1e-30 106.8 35.4 5.2e-23 81.5 16.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KIY67110.1 - 1.6e-06 26.8 2.0 1.6e-06 26.8 2.0 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 KIY67110.1 - 0.0021 16.4 6.4 0.011 14.0 5.0 2.3 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.7 KIY67110.1 - 0.032 13.1 13.5 0.14 11.0 3.6 2.2 2 0 0 2 2 2 0 MFS_1 like family HAT_KAT11 PF08214.11 KIY67111.1 - 3.3e-42 145.0 0.0 4.6e-42 144.6 0.0 1.1 1 0 0 1 1 1 1 Histone acetylation protein Fcf2 PF08698.11 KIY67113.1 - 3e-29 101.2 0.0 6.9e-29 100.1 0.0 1.6 1 0 0 1 1 1 1 Fcf2 pre-rRNA processing AF-4 PF05110.13 KIY67113.1 - 0.06 11.4 11.3 0.08 11.0 11.3 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein IMUP PF15761.5 KIY67113.1 - 0.064 14.0 5.7 0.19 12.4 5.7 1.8 1 0 0 1 1 1 0 Immortalisation up-regulated protein Mito_carr PF00153.27 KIY67114.1 - 1.1e-54 182.3 2.8 3.3e-20 71.8 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein HTH_Tnp_Tc5 PF03221.16 KIY67115.1 - 3.8e-15 55.7 0.1 6.9e-15 54.8 0.1 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_23 PF13384.6 KIY67115.1 - 0.0009 19.0 2.4 0.41 10.5 0.1 3.2 3 0 0 3 3 3 2 Homeodomain-like domain Sigma70_r4 PF04545.16 KIY67115.1 - 0.0026 17.2 0.1 2.1 7.9 0.0 2.4 2 0 0 2 2 2 2 Sigma-70, region 4 CENP-B_N PF04218.13 KIY67115.1 - 0.0075 15.9 0.0 0.049 13.3 0.0 2.0 2 0 0 2 2 2 1 CENP-B N-terminal DNA-binding domain MarR_2 PF12802.7 KIY67115.1 - 0.019 14.8 0.0 1.2 9.1 0.0 2.4 2 0 0 2 2 2 0 MarR family HTH_3 PF01381.22 KIY67115.1 - 0.067 13.3 0.1 0.95 9.6 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix HTH_38 PF13936.6 KIY67115.1 - 0.09 12.5 0.5 1.9 8.3 0.1 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_36 PF13730.6 KIY67115.1 - 0.12 12.4 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Neisseria_TspB PF05616.13 KIY67115.1 - 0.87 8.0 6.4 1.3 7.4 6.4 1.2 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein PH_4 PF15404.6 KIY67116.1 - 4.6e-18 65.6 0.1 9.9e-09 35.2 0.0 3.0 2 1 1 3 3 3 2 Pleckstrin homology domain PH PF00169.29 KIY67116.1 - 0.012 16.1 0.1 8 7.0 0.0 3.1 3 0 0 3 3 3 0 PH domain PH_9 PF15410.6 KIY67116.1 - 0.089 13.2 0.4 5.6 7.4 0.0 3.2 3 0 0 3 3 3 0 Pleckstrin homology domain RRM_1 PF00076.22 KIY67117.1 - 1.4e-16 60.1 0.0 2.4e-16 59.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RL PF17797.1 KIY67117.1 - 0.013 15.5 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 RL domain PhoU PF01895.19 KIY67118.1 - 0.15 12.6 0.0 0.32 11.5 0.0 1.5 1 0 0 1 1 1 0 PhoU domain COesterase PF00135.28 KIY67119.1 - 5.4e-75 253.2 0.0 7.4e-75 252.8 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KIY67119.1 - 5.5e-08 32.9 0.1 2.1e-07 31.0 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KIY67119.1 - 0.096 12.1 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family p450 PF00067.22 KIY67120.1 - 6.6e-67 226.2 0.0 1.7e-66 224.9 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 Sas10 PF09368.10 KIY67121.1 - 4.2e-27 94.4 4.3 4.2e-27 94.4 4.3 2.9 4 0 0 4 4 4 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 KIY67121.1 - 7.8e-06 26.4 0.3 7.8e-06 26.4 0.3 2.3 2 0 0 2 2 2 1 Sas10/Utp3/C1D family Ribosom_S12_S23 PF00164.25 KIY67122.1 - 3.2e-31 107.3 0.9 3.9e-31 107.0 0.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Prok-E2_D PF14460.6 KIY67122.1 - 0.0056 16.4 0.1 0.023 14.4 0.1 1.8 2 0 0 2 2 2 1 Prokaryotic E2 family D DUF2462 PF09495.10 KIY67123.1 - 3.3e-21 75.8 10.8 3.7e-21 75.7 10.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2462) NAD_binding_10 PF13460.6 KIY67124.1 - 2.3e-13 50.5 0.0 1.2e-12 48.1 0.0 1.9 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 KIY67124.1 - 2.2e-11 43.8 0.0 2.9e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KIY67124.1 - 2.1e-10 40.5 0.1 1.3e-09 37.9 0.1 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KIY67124.1 - 1.1e-09 37.7 0.0 1.1e-08 34.4 0.0 2.0 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KIY67124.1 - 7.9e-08 31.7 0.0 6.7e-06 25.4 0.0 2.5 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KIY67124.1 - 9.1e-06 25.0 0.2 0.00031 20.0 0.0 2.3 2 1 0 2 2 2 1 Male sterility protein GDP_Man_Dehyd PF16363.5 KIY67124.1 - 0.0052 16.2 0.0 0.0074 15.7 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 KIY67124.1 - 0.013 14.9 0.0 0.025 14.0 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase KR PF08659.10 KIY67124.1 - 0.039 13.9 0.0 0.14 12.1 0.0 1.9 3 0 0 3 3 3 0 KR domain adh_short_C2 PF13561.6 KIY67124.1 - 0.058 12.9 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.15 KIY67124.1 - 0.16 11.0 0.0 0.38 9.8 0.0 1.6 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Tom22 PF04281.13 KIY67125.1 - 3.1e-37 127.4 1.3 3.5e-37 127.3 1.3 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 MatE PF01554.18 KIY67125.1 - 0.13 11.9 0.0 0.17 11.5 0.0 1.1 1 0 0 1 1 1 0 MatE Zn_clus PF00172.18 KIY67126.1 - 6e-09 35.9 10.5 9.4e-09 35.3 10.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KIY67126.1 - 0.00019 20.6 0.2 0.0016 17.5 0.1 2.3 2 1 0 2 2 2 1 Fungal specific transcription factor domain Pet127 PF08634.10 KIY67127.1 - 3.8e-99 331.6 0.1 5.5e-99 331.0 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial protein Pet127 DUF4686 PF15742.5 KIY67128.1 - 0.011 14.9 7.3 0.021 14.0 7.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4686) Fez1 PF06818.15 KIY67128.1 - 0.59 10.6 4.5 1.4 9.3 4.1 1.7 1 1 0 1 1 1 0 Fez1 Spc7 PF08317.11 KIY67128.1 - 0.82 8.5 9.0 0.2 10.5 1.4 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein HIP1_clath_bdg PF16515.5 KIY67128.1 - 2.1 9.0 7.1 0.67 10.6 3.5 2.1 2 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 RPN13_C PF16550.5 KIY67130.1 - 3e-25 88.6 0.0 5.6e-25 87.7 0.0 1.5 1 1 0 1 1 1 1 UCH-binding domain Proteasom_Rpn13 PF04683.13 KIY67130.1 - 3.1e-23 82.1 0.0 4.4e-23 81.6 0.0 1.2 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor DUF2205 PF10224.9 KIY67131.1 - 3.5e-09 36.5 1.3 4.3e-09 36.2 1.3 1.1 1 0 0 1 1 1 1 Short coiled-coil protein Paramyxo_P PF01806.17 KIY67131.1 - 0.0041 16.6 0.3 0.0048 16.4 0.3 1.0 1 0 0 1 1 1 1 Paramyxovirinae P phosphoprotein C-terminal region YabA PF06156.13 KIY67131.1 - 0.011 16.3 0.6 0.012 16.2 0.6 1.1 1 0 0 1 1 1 0 Initiation control protein YabA RBD-FIP PF09457.10 KIY67131.1 - 0.021 14.8 0.8 0.04 13.8 0.0 1.7 2 0 0 2 2 2 0 FIP domain Herpes_IE2_3 PF03361.14 KIY67131.1 - 0.04 13.8 0.0 0.042 13.7 0.0 1.1 1 0 0 1 1 1 0 Herpes virus intermediate/early protein 2/3 gpW PF02831.15 KIY67131.1 - 0.056 13.3 1.3 0.088 12.7 1.3 1.3 1 0 0 1 1 1 0 gpW Endotoxin_C2 PF18449.1 KIY67131.1 - 0.058 13.7 3.5 1.2 9.5 0.4 2.2 2 0 0 2 2 2 0 Delta endotoxin DivIC PF04977.15 KIY67131.1 - 0.18 11.6 1.9 0.23 11.2 1.9 1.2 1 0 0 1 1 1 0 Septum formation initiator F-box-like PF12937.7 KIY67132.1 - 9.6e-07 28.6 1.3 2.2e-06 27.5 0.5 1.9 2 0 0 2 2 2 1 F-box-like DUF155 PF02582.14 KIY67133.1 - 9.5e-49 165.9 0.1 2.2e-48 164.7 0.0 1.6 2 0 0 2 2 2 1 Uncharacterised ACR, YagE family COG1723 CAF1A PF12253.8 KIY67133.1 - 0.18 12.0 1.3 1 9.6 0.0 2.3 2 0 0 2 2 2 0 Chromatin assembly factor 1 subunit A zinc_ribbon_16 PF17034.5 KIY67134.1 - 3.7e-18 65.9 6.3 7.5e-18 64.9 6.3 1.5 1 0 0 1 1 1 1 Zinc-ribbon like family WD40 PF00400.32 KIY67134.1 - 0.0015 19.3 0.6 39 5.3 0.0 5.5 5 0 0 5 5 5 0 WD domain, G-beta repeat DUF3653 PF12375.8 KIY67134.1 - 0.14 12.3 0.0 0.43 10.7 0.0 1.8 1 0 0 1 1 1 0 Phage protein Zn_ribbon_recom PF13408.6 KIY67134.1 - 0.22 12.0 3.2 0.74 10.4 3.2 1.9 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain Zn_ribbon_17 PF17120.5 KIY67134.1 - 0.5 10.0 13.3 0.042 13.5 7.5 2.1 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type GIDA PF01134.22 KIY67135.1 - 5.1e-150 499.9 0.0 6.3e-150 499.6 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 KIY67135.1 - 8.6e-59 199.2 0.0 1.4e-58 198.5 0.0 1.3 1 0 0 1 1 1 1 GidA associated domain Pyr_redox_2 PF07992.14 KIY67135.1 - 5.7e-07 29.1 0.7 3e-06 26.7 0.2 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KIY67135.1 - 5.8e-06 25.9 0.1 1e-05 25.1 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KIY67135.1 - 0.00043 19.5 0.7 0.00085 18.5 0.7 1.5 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KIY67135.1 - 0.00085 18.1 0.6 0.076 11.7 0.2 2.4 2 0 0 2 2 2 2 HI0933-like protein AlaDh_PNT_C PF01262.21 KIY67135.1 - 0.0052 16.1 0.1 0.011 15.1 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 KIY67135.1 - 0.01 16.4 0.2 0.032 14.8 0.2 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KIY67135.1 - 0.084 12.1 0.0 0.21 10.8 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIY67135.1 - 0.11 12.1 0.3 2.9 7.4 0.3 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KIY67135.1 - 0.18 11.0 0.1 0.3 10.3 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Sdh5 PF03937.16 KIY67137.1 - 9.6e-28 96.0 0.7 1.2e-27 95.6 0.7 1.2 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase MGTL PF17059.5 KIY67137.1 - 8 6.4 14.5 1.5 8.7 1.6 3.7 3 0 0 3 3 3 0 MgtA leader peptide Prenyltrans PF00432.21 KIY67138.1 - 5.4e-55 182.8 8.6 1.3e-10 40.8 0.1 6.2 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat Usp PF00582.26 KIY67139.1 - 5.1e-20 72.4 0.1 5.1e-20 72.4 0.1 2.3 2 0 0 2 2 2 1 Universal stress protein family Thioesterase PF00975.20 KIY67140.1 - 3.9e-06 27.1 0.1 7.9e-06 26.2 0.0 1.5 2 0 0 2 2 2 1 Thioesterase domain Cullin PF00888.22 KIY67142.1 - 7.2e-177 589.7 6.4 9.4e-177 589.4 6.4 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KIY67142.1 - 2e-26 91.8 1.0 2e-26 91.8 1.0 2.1 2 0 0 2 2 2 1 Cullin protein neddylation domain MFS_1 PF07690.16 KIY67143.1 - 4.2e-18 65.4 19.9 4.9e-18 65.2 19.9 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily DIOX_N PF14226.6 KIY67144.1 - 3.9e-15 56.6 0.0 8.1e-15 55.6 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KIY67144.1 - 8.2e-14 51.9 0.1 1.6e-13 51.0 0.1 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ERF PF04404.12 KIY67144.1 - 0.005 16.7 0.1 0.044 13.6 0.0 2.1 2 0 0 2 2 2 1 ERF superfamily Polysacc_deac_1 PF01522.21 KIY67145.1 - 2.5e-31 108.2 0.0 4.7e-31 107.3 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase WW PF00397.26 KIY67146.1 - 7.4e-05 22.8 3.1 0.00016 21.7 3.1 1.6 1 0 0 1 1 1 1 WW domain DUF2196 PF09962.9 KIY67147.1 - 0.056 13.4 0.1 3.9 7.5 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2196) Pkinase PF00069.25 KIY67148.1 - 1.1e-57 195.4 0.0 1.3e-57 195.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY67148.1 - 8.3e-14 51.5 0.0 1.1e-13 51.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KIY67148.1 - 3.1e-06 27.3 0.1 0.00028 20.9 0.1 2.3 1 1 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KIY67148.1 - 0.0028 16.5 0.0 0.0044 15.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KIY67148.1 - 0.0071 15.7 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KIY67148.1 - 0.032 13.8 0.0 0.062 12.9 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Ribosomal_S8e PF01201.22 KIY67149.1 - 4.3e-56 188.9 1.3 6.6e-56 188.3 1.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S8e An_peroxidase PF03098.15 KIY67149.1 - 0.023 13.3 0.2 1.1 7.8 0.1 2.0 2 0 0 2 2 2 0 Animal haem peroxidase Metallophos PF00149.28 KIY67150.1 - 3e-09 37.7 0.0 4.5e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ALAD PF00490.21 KIY67151.1 - 1.3e-121 405.7 0.0 1.5e-121 405.4 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase HP1451_C PF18472.1 KIY67151.1 - 0.13 12.2 0.1 0.26 11.3 0.1 1.4 1 0 0 1 1 1 0 HP1451 C-terminal domain LSM PF01423.22 KIY67152.1 - 3.4e-15 55.5 0.2 4.4e-15 55.1 0.2 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KIY67152.1 - 0.015 15.4 0.0 0.018 15.2 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain Fungal_trans PF04082.18 KIY67153.1 - 4.7e-19 68.4 0.0 8.1e-19 67.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY67153.1 - 0.0002 21.4 15.1 0.00038 20.5 15.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1335 PF07056.11 KIY67153.1 - 0.0083 16.2 0.0 0.017 15.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1335) BSD PF03909.17 KIY67154.1 - 5.4e-08 32.7 0.1 6.3e-07 29.3 0.0 2.4 2 0 0 2 2 2 1 BSD domain CPSase_sm_chain PF00988.22 KIY67155.1 - 8.6e-45 151.7 0.0 1.4e-44 151.0 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 KIY67155.1 - 5.4e-37 127.4 0.0 7.2e-37 127.0 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KIY67155.1 - 3.3e-08 33.6 0.3 2.6e-06 27.3 0.3 2.8 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.24 KIY67155.1 - 0.0081 16.0 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 DJ-1/PfpI family Nse4_C PF08743.10 KIY67157.1 - 3.8e-27 94.4 0.1 3.8e-27 94.4 0.1 1.9 2 0 0 2 2 2 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 KIY67157.1 - 2.5e-15 56.3 0.3 5.2e-15 55.3 0.3 1.5 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE SNF2_N PF00176.23 KIY67158.1 - 1.6e-65 221.1 0.0 2.8e-65 220.3 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 KIY67158.1 - 3.5e-19 68.5 0.0 9.1e-19 67.2 0.0 1.7 1 0 0 1 1 1 1 HIRAN domain zf-PARP PF00645.18 KIY67158.1 - 2.5e-12 47.5 0.0 7.2e-12 46.0 0.0 1.9 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Helicase_C PF00271.31 KIY67158.1 - 1.5e-11 44.6 0.0 2.5e-05 24.6 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 KIY67158.1 - 5.3e-09 36.3 0.0 1.3e-08 35.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 KIY67158.1 - 1.7e-07 31.0 6.6 3.7e-07 29.9 6.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIY67158.1 - 6.1e-07 29.7 5.7 1.3e-06 28.7 5.7 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KIY67158.1 - 7.2e-06 25.8 7.2 1.3e-05 24.9 7.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIY67158.1 - 1.1e-05 25.3 7.4 2.2e-05 24.3 7.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KIY67158.1 - 1.3e-05 24.9 6.3 1.3e-05 24.9 6.3 1.8 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.29 KIY67158.1 - 5.2e-05 23.1 0.0 0.00011 22.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-rbx1 PF12678.7 KIY67158.1 - 6e-05 23.2 4.9 0.00015 22.0 4.9 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KIY67158.1 - 0.00039 20.4 2.1 0.00078 19.4 2.1 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 KIY67158.1 - 0.0027 17.7 7.1 0.0056 16.7 7.1 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KIY67158.1 - 0.039 13.8 7.2 0.051 13.4 5.8 1.9 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 WW PF00397.26 KIY67158.1 - 0.039 14.0 0.3 0.095 12.8 0.3 1.6 1 0 0 1 1 1 0 WW domain zf-RING_4 PF14570.6 KIY67158.1 - 0.052 13.4 3.9 0.13 12.1 3.9 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF1272 PF06906.11 KIY67158.1 - 0.14 12.3 5.3 0.26 11.4 5.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-RING_11 PF17123.5 KIY67158.1 - 0.97 9.2 6.6 1.9 8.3 6.6 1.5 1 0 0 1 1 1 0 RING-like zinc finger zf-C3HC4_4 PF15227.6 KIY67158.1 - 2.5 8.3 5.9 7.2 6.9 5.9 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING RicinB_lectin_2 PF14200.6 KIY67159.1 - 2.8e-21 76.0 6.2 2.2e-11 44.3 0.3 2.5 1 1 2 3 3 3 3 Ricin-type beta-trefoil lectin domain-like SpaA PF17802.1 KIY67159.1 - 0.0021 18.3 0.1 0.0044 17.3 0.0 1.6 2 0 0 2 2 2 1 Prealbumin-like fold domain DUF5633 PF18656.1 KIY67159.1 - 0.0066 16.3 0.5 0.015 15.2 0.2 1.7 1 1 0 1 1 1 1 Family of unknown function (DUF5633) DIPSY PF11763.8 KIY67159.1 - 0.085 13.0 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 Cell-wall adhesin ligand-binding C-terminal UDPGP PF01704.18 KIY67160.1 - 1e-194 647.0 0.8 1.2e-194 646.8 0.8 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase XPG_I PF00867.18 KIY67163.1 - 3.6e-06 27.2 0.0 5.9e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 XPG I-region DUF3135 PF11333.8 KIY67163.1 - 0.098 12.9 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3135) SAP PF02037.27 KIY67165.1 - 0.0026 17.5 0.1 0.0055 16.4 0.1 1.5 1 0 0 1 1 1 1 SAP domain Phage_HK97_TLTM PF06120.11 KIY67166.1 - 0.047 12.9 1.2 0.13 11.4 1.0 1.8 2 0 0 2 2 2 0 Tail length tape measure protein FliT PF05400.13 KIY67166.1 - 0.14 13.0 10.4 0.071 13.9 8.0 1.8 2 0 0 2 2 2 0 Flagellar protein FliT Ribosomal_S7 PF00177.21 KIY67167.1 - 4.6e-36 123.7 2.4 5.6e-36 123.4 2.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e DUF1318 PF07027.12 KIY67168.1 - 1.6 9.3 4.6 1.2 9.6 0.2 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1318) Ndc1_Nup PF09531.10 KIY67169.1 - 2.9 6.5 10.7 0.41 9.3 0.6 2.1 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup WD40 PF00400.32 KIY67170.1 - 1.8e-28 98.2 11.3 2e-05 25.2 0.0 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY67170.1 - 4.8e-08 33.2 0.1 0.2 12.0 0.0 4.7 1 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KIY67170.1 - 7.4e-05 22.2 0.1 0.01 15.2 0.0 2.9 2 1 1 3 3 3 1 WD40-like domain PQQ_2 PF13360.6 KIY67170.1 - 0.0034 17.0 0.7 0.062 12.9 0.3 2.7 1 1 2 3 3 3 3 PQQ-like domain DUF5046 PF16465.5 KIY67170.1 - 0.011 15.2 0.1 0.68 9.3 0.0 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF5046) BBS2_Mid PF14783.6 KIY67170.1 - 0.033 14.2 0.0 5.2 7.2 0.0 3.5 4 1 1 5 5 5 0 Ciliary BBSome complex subunit 2, middle region PQQ PF01011.21 KIY67170.1 - 0.041 13.8 0.0 17 5.6 0.0 3.5 4 0 0 4 4 4 0 PQQ enzyme repeat Me-amine-dh_H PF06433.11 KIY67170.1 - 0.13 11.1 0.0 0.23 10.3 0.0 1.5 1 0 0 1 1 1 0 Methylamine dehydrogenase heavy chain (MADH) F-box-like PF12937.7 KIY67171.1 - 1.4e-06 28.1 1.2 4.3e-06 26.5 1.2 1.9 1 0 0 1 1 1 1 F-box-like PAN_1 PF00024.26 KIY67172.1 - 0.019 14.9 0.8 0.035 14.1 0.8 1.5 1 0 0 1 1 1 0 PAN domain PAN_4 PF14295.6 KIY67172.1 - 0.052 13.5 1.1 0.052 13.5 1.1 1.8 2 0 0 2 2 2 0 PAN domain EPF PF17181.4 KIY67172.1 - 0.21 11.6 1.4 0.45 10.6 1.4 1.4 1 0 0 1 1 1 0 Epidermal patterning factor proteins Scs3p PF10261.9 KIY67173.1 - 3.5e-43 147.9 8.3 3.8e-34 118.3 0.3 2.1 1 1 1 2 2 2 2 Inositol phospholipid synthesis and fat-storage-inducing TM Mito_carr PF00153.27 KIY67174.1 - 3e-17 62.3 7.0 1.9e-08 34.1 0.4 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein RskA PF10099.9 KIY67174.1 - 0.14 12.5 0.8 2.1 8.6 0.1 2.4 2 1 0 2 2 2 0 Anti-sigma-K factor rskA NmrA PF05368.13 KIY67175.1 - 1.7e-29 103.1 0.0 2.1e-29 102.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KIY67175.1 - 5.9e-15 55.6 0.1 1.9e-14 54.0 0.1 1.8 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KIY67175.1 - 2.3e-05 24.0 0.0 3.5e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KIY67175.1 - 9.5e-05 22.7 0.0 0.00017 21.9 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 KIY67175.1 - 0.00053 20.0 0.0 0.0009 19.2 0.0 1.3 1 0 0 1 1 1 1 KR domain Semialdhyde_dh PF01118.24 KIY67175.1 - 0.0009 19.7 0.1 0.0016 18.9 0.1 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KIY67175.1 - 0.00093 18.3 0.0 0.0015 17.6 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KIY67175.1 - 0.0043 16.3 0.0 0.0073 15.5 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Shikimate_DH PF01488.20 KIY67175.1 - 0.0057 16.7 0.1 0.015 15.4 0.0 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase GDP_Man_Dehyd PF16363.5 KIY67175.1 - 0.022 14.2 0.0 0.035 13.5 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase DapB_N PF01113.20 KIY67175.1 - 0.031 14.4 0.1 0.053 13.6 0.1 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus AlaDh_PNT_C PF01262.21 KIY67175.1 - 0.044 13.1 0.3 0.095 12.0 0.1 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Acetyltransf_3 PF13302.7 KIY67176.1 - 9.8e-16 58.7 0.0 1.2e-15 58.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIY67176.1 - 9.4e-07 29.1 0.1 1.4e-06 28.6 0.1 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 KIY67176.1 - 0.0032 17.2 0.0 0.0075 16.0 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain DMA PF03474.14 KIY67176.1 - 0.023 14.3 0.0 0.04 13.5 0.0 1.3 1 0 0 1 1 1 0 DMRTA motif Acetyltransf_7 PF13508.7 KIY67176.1 - 0.077 13.4 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain ARPC4 PF05856.12 KIY67177.1 - 4.3e-79 263.9 6.8 4.8e-79 263.8 6.8 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) FKBP_C PF00254.28 KIY67178.1 - 2.2e-32 111.2 0.1 5.6e-32 109.9 0.1 1.7 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 KIY67178.1 - 2.5e-14 53.7 1.6 7.6e-14 52.2 0.0 2.2 2 0 0 2 2 2 1 Nucleoplasmin-like domain RCR PF12273.8 KIY67178.1 - 0.1 13.3 1.6 0.27 11.9 1.6 1.7 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red YL1 PF05764.13 KIY67178.1 - 3.6 7.6 24.6 0.87 9.7 15.4 2.1 2 0 0 2 2 2 0 YL1 nuclear protein Yae1_N PF09811.9 KIY67179.1 - 0.0034 17.1 8.5 0.018 14.7 3.5 2.8 3 0 0 3 3 3 1 Essential protein Yae1, N terminal Amidohydro_2 PF04909.14 KIY67179.1 - 0.046 13.5 0.0 0.082 12.7 0.0 1.5 1 0 0 1 1 1 0 Amidohydrolase DUF4795 PF16043.5 KIY67179.1 - 0.12 12.0 4.9 0.19 11.3 4.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) DUF4326 PF14216.6 KIY67179.1 - 0.12 13.1 0.8 0.27 12.0 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4326) GAS PF13851.6 KIY67179.1 - 0.7 9.2 14.8 0.91 8.8 13.8 1.6 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding MCU PF04678.13 KIY67179.1 - 1.1 9.4 5.7 2 8.5 5.7 1.4 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Spc7 PF08317.11 KIY67179.1 - 1.5 7.6 14.5 2.3 7.0 14.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Exonuc_VII_L PF02601.15 KIY67179.1 - 1.8 8.0 10.6 2.7 7.5 10.6 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit V_ATPase_I PF01496.19 KIY67179.1 - 7.2 4.4 7.1 9.3 4.0 7.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family BST2 PF16716.5 KIY67179.1 - 9.8 6.8 11.5 11 6.7 8.1 2.2 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 Glyco_hydro_1 PF00232.18 KIY67180.1 - 5.8e-151 502.9 0.3 7.1e-151 502.7 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Glyco_hydro_cc PF11790.8 KIY67180.1 - 0.079 12.5 0.0 3.3 7.2 0.0 2.5 2 1 1 3 3 3 0 Glycosyl hydrolase catalytic core Mersacidin PF16934.5 KIY67180.1 - 0.088 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Two-component Enterococcus faecalis cytolysin (EFC) SET PF00856.28 KIY67181.1 - 1.7e-12 48.1 0.1 1.7e-11 44.8 0.0 2.4 2 1 0 2 2 2 1 SET domain Stm1_N PF09598.10 KIY67181.1 - 1.1 10.2 7.8 3.3 8.6 7.8 1.8 1 0 0 1 1 1 0 Stm1 AbiJ_NTD4 PF18863.1 KIY67182.1 - 0.0055 17.2 1.2 0.032 14.7 1.1 2.0 2 0 0 2 2 2 1 AbiJ N-terminal domain 4 F-box PF00646.33 KIY67182.1 - 0.021 14.7 0.1 2 8.4 0.0 2.9 3 0 0 3 3 3 0 F-box domain IGR PF09597.10 KIY67183.1 - 0.13 12.4 0.0 0.35 11.0 0.0 1.7 1 0 0 1 1 1 0 IGR protein motif DUF3825 PF12873.7 KIY67183.1 - 0.14 11.6 0.1 0.23 10.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3825) Pyrophosphatase PF00719.19 KIY67185.1 - 7.6e-59 198.1 0.1 9.6e-59 197.8 0.1 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase GCP_C_terminal PF04130.13 KIY67186.1 - 2.5e-30 106.0 0.1 4.4e-30 105.2 0.1 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KIY67186.1 - 1.3e-20 74.3 0.1 1.1e-18 67.9 0.0 2.6 2 1 0 2 2 2 1 Gamma tubulin complex component N-terminal UvrD-helicase PF00580.21 KIY67187.1 - 1.5e-62 211.9 0.0 3.3e-62 210.8 0.0 1.5 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 KIY67187.1 - 1.7e-33 116.0 0.0 2.8e-33 115.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain UvrD_C PF13361.6 KIY67187.1 - 3.2e-32 112.3 0.0 2.4e-31 109.4 0.0 2.2 3 0 0 3 3 3 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 KIY67187.1 - 2.3e-05 24.2 0.0 0.0025 17.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 KIY67187.1 - 8.7e-05 22.4 0.1 0.16 11.7 0.0 2.3 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.6 KIY67187.1 - 0.013 15.3 1.0 0.028 14.2 0.3 1.8 2 1 0 2 2 2 0 AAA domain UPF0149 PF03695.13 KIY67187.1 - 0.13 12.5 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0149) ApbA_C PF08546.11 KIY67188.1 - 3.9e-23 82.0 0.0 6.9e-23 81.2 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 KIY67188.1 - 3.9e-13 49.3 0.0 8e-13 48.3 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Aldo_ket_red PF00248.21 KIY67189.1 - 8.2e-42 143.4 0.0 1.5e-41 142.5 0.0 1.4 1 1 0 1 1 1 1 Aldo/keto reductase family PB1 PF00564.24 KIY67190.1 - 1.2e-11 44.4 0.0 2.3e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 PB1 domain TEA PF01285.18 KIY67191.1 - 3e-22 78.4 0.0 5.2e-22 77.7 0.0 1.4 1 0 0 1 1 1 1 TEA/ATTS domain Collagen_mid PF15984.5 KIY67192.1 - 0.024 14.4 0.1 0.036 13.8 0.1 1.2 1 0 0 1 1 1 0 Bacterial collagen, middle region Ceramidase_alk PF04734.13 KIY67193.1 - 8.4e-212 704.3 0.1 9.9e-212 704.1 0.1 1.1 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 KIY67193.1 - 5.8e-51 172.7 0.4 1e-50 171.9 0.4 1.4 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal F-box-like PF12937.7 KIY67194.1 - 1.9e-08 34.0 0.0 6.7e-08 32.3 0.0 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY67194.1 - 7.7e-05 22.5 0.5 0.00045 20.0 0.1 2.5 2 0 0 2 2 2 1 F-box domain MMR_HSR1 PF01926.23 KIY67195.1 - 1.7e-15 57.1 0.0 1.1e-14 54.5 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KIY67195.1 - 3.4e-06 26.7 0.0 7.4e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KIY67195.1 - 0.00026 20.9 0.0 0.006 16.5 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 KIY67195.1 - 0.0015 18.6 0.7 0.0093 16.0 0.2 2.3 1 1 1 2 2 2 1 Dynamin family PduV-EutP PF10662.9 KIY67195.1 - 0.091 12.5 0.0 2.2 8.0 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AIG1 PF04548.16 KIY67195.1 - 0.097 12.0 0.0 0.44 9.8 0.0 1.9 2 0 0 2 2 2 0 AIG1 family Roc PF08477.13 KIY67195.1 - 0.14 12.4 0.1 0.59 10.4 0.0 1.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Methyltransf_25 PF13649.6 KIY67197.1 - 1.1e-15 58.1 0.0 2.2e-15 57.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIY67197.1 - 3.5e-13 50.0 0.0 6.6e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIY67197.1 - 4.9e-09 35.9 0.0 7.6e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KIY67197.1 - 2.2e-08 34.1 0.0 5.2e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIY67197.1 - 2.2e-05 24.3 0.0 6.7e-05 22.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIY67197.1 - 4.6e-05 24.1 0.0 0.00011 22.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KIY67197.1 - 6.3e-05 22.4 0.0 0.00011 21.6 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_4 PF02390.17 KIY67197.1 - 0.0021 17.6 0.0 0.0087 15.5 0.0 2.0 3 0 0 3 3 3 1 Putative methyltransferase CMAS PF02353.20 KIY67197.1 - 0.0065 15.8 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_29 PF03141.16 KIY67197.1 - 0.012 14.2 0.0 0.017 13.7 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase MetW PF07021.12 KIY67197.1 - 0.081 12.5 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW FtsJ PF01728.19 KIY67197.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase DUF3071 PF11268.8 KIY67197.1 - 0.15 12.2 0.1 0.32 11.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3071) MTS PF05175.14 KIY67197.1 - 0.16 11.5 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_8 PF05148.15 KIY67197.1 - 0.18 11.7 0.0 0.62 9.9 0.0 1.8 1 1 0 1 1 1 0 Hypothetical methyltransferase WD40 PF00400.32 KIY67198.1 - 2.6e-19 69.2 10.3 0.0061 17.4 0.1 8.5 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY67198.1 - 6.1e-05 23.3 0.1 6.5 7.1 0.0 5.1 5 1 1 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KIY67198.1 - 0.038 13.3 0.0 0.077 12.3 0.0 1.5 1 0 0 1 1 1 0 WD40-like domain DUF1883 PF08980.10 KIY67198.1 - 0.17 11.8 0.1 1.2 9.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1883) YccV-like PF08755.11 KIY67199.1 - 8.1e-21 74.4 0.1 1.9e-20 73.2 0.0 1.6 2 0 0 2 2 2 1 Hemimethylated DNA-binding protein YccV like Transglut_core2 PF13369.6 KIY67199.1 - 4.9e-09 35.9 0.0 8.1e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 Transglutaminase-like superfamily F-box-like PF12937.7 KIY67199.1 - 0.0043 16.9 0.1 0.02 14.8 0.1 2.2 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY67199.1 - 0.037 13.9 0.7 0.18 11.7 0.1 2.5 2 0 0 2 2 2 0 F-box domain Nop52 PF05997.12 KIY67200.1 - 2.8e-69 233.2 0.0 3.9e-69 232.7 0.0 1.2 1 0 0 1 1 1 1 Nucleolar protein,Nop52 MMS19_N PF14500.6 KIY67200.1 - 1.2e-05 25.0 0.0 0.0001 22.0 0.0 2.0 2 0 0 2 2 2 1 Dos2-interacting transcription regulator of RNA-Pol-II Transthyretin PF00576.21 KIY67201.1 - 1.7e-34 118.8 0.0 3.8e-34 117.7 0.0 1.5 1 1 0 1 1 1 1 HIUase/Transthyretin family CarboxypepD_reg PF13620.6 KIY67201.1 - 0.018 15.3 0.0 0.075 13.3 0.0 2.0 1 1 0 1 1 1 0 Carboxypeptidase regulatory-like domain DUF2057 PF09829.9 KIY67201.1 - 0.14 12.3 0.0 0.19 11.9 0.0 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) UQ_con PF00179.26 KIY67202.1 - 7.9e-39 132.5 0.1 1e-38 132.2 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 KIY67202.1 - 0.045 13.6 0.1 0.071 13.0 0.1 1.4 1 1 0 1 1 1 0 UEV domain RWD PF05773.22 KIY67202.1 - 0.084 13.2 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 RWD domain F-box-like PF12937.7 KIY67203.1 - 1.6e-07 31.1 0.3 1.6e-07 31.1 0.3 2.8 4 0 0 4 4 4 1 F-box-like F-box PF00646.33 KIY67203.1 - 0.047 13.6 0.3 0.047 13.6 0.3 2.4 2 0 0 2 2 2 0 F-box domain APG6_N PF17675.1 KIY67204.1 - 0.0031 18.0 0.8 0.0074 16.8 0.8 1.6 1 0 0 1 1 1 1 Apg6 coiled-coil region GAS PF13851.6 KIY67204.1 - 0.075 12.4 0.2 0.2 11.0 0.2 1.6 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Chorismate_bind PF00425.18 KIY67205.1 - 4.2e-70 236.3 0.0 5.8e-70 235.8 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.28 KIY67205.1 - 5.9e-27 94.7 0.0 8.8e-27 94.1 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 KIY67205.1 - 3.6e-12 46.7 0.0 2e-11 44.3 0.0 2.0 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 KIY67205.1 - 0.00013 21.8 0.0 0.00026 20.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase C26 RTP1_C1 PF10363.9 KIY67206.1 - 0.074 13.2 0.0 2 8.6 0.0 2.7 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 MMS19_N PF14500.6 KIY67206.1 - 0.15 11.6 0.6 1.8 8.1 0.0 2.7 3 0 0 3 3 3 0 Dos2-interacting transcription regulator of RNA-Pol-II HEAT PF02985.22 KIY67206.1 - 2.2 8.8 7.4 0.84 10.1 0.1 4.0 5 0 0 5 5 5 0 HEAT repeat dCMP_cyt_deam_1 PF00383.23 KIY67207.1 - 4.6e-26 90.7 2.5 6.7e-26 90.1 2.5 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KIY67207.1 - 1.6e-14 53.9 0.4 2.4e-14 53.3 0.4 1.2 1 0 0 1 1 1 1 MafB19-like deaminase MGAT2 PF05060.14 KIY67207.1 - 0.11 11.5 0.3 0.16 11.0 0.3 1.2 1 0 0 1 1 1 0 N-acetylglucosaminyltransferase II (MGAT2) SNAD4 PF18750.1 KIY67207.1 - 0.24 11.6 1.3 0.46 10.6 1.3 1.5 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 RNase_P_pop3 PF08228.11 KIY67208.1 - 2.7e-16 60.0 0.3 8.7e-11 42.1 0.0 2.8 2 1 0 2 2 2 2 RNase P subunit Pop3 Arrestin_C PF02752.22 KIY67209.1 - 9.5e-11 42.3 0.0 5.1e-10 39.9 0.0 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KIY67209.1 - 0.045 13.8 0.0 0.14 12.2 0.0 1.9 1 0 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain Vta1 PF04652.16 KIY67210.1 - 5.1e-47 159.5 0.6 5.7e-47 159.3 0.6 1.0 1 0 0 1 1 1 1 Vta1 like Zw10 PF06248.13 KIY67211.1 - 0.092 11.3 0.3 0.13 10.8 0.3 1.1 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 Amidohydro_3 PF07969.11 KIY67212.1 - 1.4e-81 275.4 0.0 1.7e-81 275.1 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 KIY67212.1 - 1e-09 38.2 0.0 5.4e-09 35.8 0.0 1.9 2 0 0 2 2 2 1 Amidohydrolase family ScsC_N PF18312.1 KIY67212.1 - 0.026 14.3 0.3 0.049 13.4 0.3 1.4 1 0 0 1 1 1 0 Copper resistance protein ScsC N-terminal domain Peptidase_M3 PF01432.20 KIY67213.1 - 2.6e-132 442.4 0.0 3.2e-132 442.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 MFS_1 PF07690.16 KIY67214.1 - 6.5e-37 127.3 35.3 6.5e-37 127.3 35.3 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIY67214.1 - 2.1e-07 30.2 12.9 2.1e-07 30.2 12.9 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter Glyco_hydro_61 PF03443.14 KIY67215.1 - 9.3e-23 81.2 0.0 2e-22 80.2 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 MIP PF00230.20 KIY67216.1 - 5.5e-41 140.7 15.3 6.9e-41 140.4 15.3 1.1 1 0 0 1 1 1 1 Major intrinsic protein DUF5381 PF17353.2 KIY67216.1 - 0.36 10.6 4.8 0.84 9.4 4.8 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5381) Pkinase PF00069.25 KIY67217.1 - 2.1e-36 125.7 0.0 3.5e-36 124.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY67217.1 - 3.1e-36 125.0 0.0 4.2e-36 124.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KIY67217.1 - 0.013 15.4 0.1 0.031 14.2 0.1 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family PMI_typeI PF01238.21 KIY67218.1 - 1.3e-116 389.9 0.0 1.5e-116 389.7 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.11 KIY67218.1 - 2.2e-05 24.1 0.1 0.039 13.7 0.0 2.3 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.19 KIY67218.1 - 2.5e-05 24.2 0.1 0.13 12.2 0.0 3.3 3 0 0 3 3 3 2 AraC-like ligand binding domain Cupin_6 PF12852.7 KIY67218.1 - 0.0065 16.2 0.0 0.19 11.5 0.0 2.3 2 0 0 2 2 2 1 Cupin AraC_N PF06719.13 KIY67218.1 - 0.056 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 AraC-type transcriptional regulator N-terminus Herpes_UL55 PF04537.12 KIY67218.1 - 0.15 12.0 0.0 0.8 9.7 0.0 1.9 1 1 1 2 2 2 0 Herpesvirus UL55 protein zf-C3HC4_3 PF13920.6 KIY67219.1 - 2.7e-10 40.0 17.5 4.1e-07 29.7 7.4 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-NOSIP PF15906.5 KIY67219.1 - 9.7e-10 38.5 0.6 2.1e-09 37.4 0.6 1.6 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-RING_UBOX PF13445.6 KIY67219.1 - 1.3e-07 31.5 15.7 0.00077 19.4 1.2 2.6 2 0 0 2 2 2 2 RING-type zinc-finger Rtf2 PF04641.12 KIY67219.1 - 3.6e-07 29.8 1.4 3.6e-07 29.8 1.4 2.6 2 1 1 3 3 3 1 Rtf2 RING-finger zf-RING_5 PF14634.6 KIY67219.1 - 7.2e-07 29.1 17.6 1.5e-05 24.8 7.4 2.6 2 0 0 2 2 2 2 zinc-RING finger domain zf-RING_2 PF13639.6 KIY67219.1 - 1.1e-06 28.8 18.1 0.0013 19.0 7.8 2.4 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_2 PF13923.6 KIY67219.1 - 1.8e-06 27.7 21.0 0.00062 19.6 10.3 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIY67219.1 - 5.9e-06 26.0 20.8 0.00087 19.1 10.0 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KIY67219.1 - 6.1e-06 26.0 19.9 8.9e-06 25.5 2.0 3.3 2 1 1 3 3 3 2 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KIY67219.1 - 0.00023 21.3 15.3 0.069 13.3 1.6 2.6 2 1 0 2 2 2 2 zinc finger of C3HC4-type, RING FYVE PF01363.21 KIY67219.1 - 0.0022 18.1 11.8 0.0022 18.1 3.2 2.7 2 1 0 2 2 2 1 FYVE zinc finger Bindin PF02084.15 KIY67219.1 - 0.036 14.4 1.0 0.058 13.7 1.0 1.3 1 0 0 1 1 1 0 Bindin FCP1_C PF09309.10 KIY67219.1 - 0.056 13.3 6.3 0.053 13.4 5.0 1.6 2 0 0 2 2 2 0 FCP1, C-terminal Asparaginase_2 PF01112.18 KIY67219.1 - 0.061 12.4 0.1 0.096 11.7 0.1 1.2 1 0 0 1 1 1 0 Asparaginase DivIC PF04977.15 KIY67219.1 - 0.19 11.5 13.4 0.049 13.4 5.3 2.2 2 0 0 2 2 2 0 Septum formation initiator DZR PF12773.7 KIY67219.1 - 1 9.4 15.1 1.1 9.4 6.3 3.0 2 1 0 2 2 2 0 Double zinc ribbon Vps39_2 PF10367.9 KIY67219.1 - 1.7 9.2 14.6 0.93 10.0 3.4 3.1 2 1 1 3 3 3 0 Vacuolar sorting protein 39 domain 2 zinc-ribbons_6 PF07191.12 KIY67219.1 - 3.2 7.8 14.5 0.48 10.4 5.5 2.6 2 0 0 2 2 2 0 zinc-ribbons Mei5 PF10376.9 KIY67219.1 - 4.3 7.1 10.9 0.039 13.8 2.1 2.0 3 0 0 3 3 3 0 Double-strand recombination repair protein Fungal_trans PF04082.18 KIY67220.1 - 2e-19 69.7 0.0 3.7e-19 68.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY67220.1 - 4.2e-07 30.0 9.7 7.7e-07 29.1 9.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Striatin PF08232.12 KIY67220.1 - 0.00015 22.4 0.3 0.00026 21.6 0.3 1.2 1 0 0 1 1 1 1 Striatin family Lar_restr_allev PF14354.6 KIY67220.1 - 4.1 7.9 7.1 2.4 8.6 4.3 2.0 2 0 0 2 2 2 0 Restriction alleviation protein Lar DUF21 PF01595.20 KIY67221.1 - 1.6e-35 122.4 0.1 2.7e-35 121.7 0.1 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 KIY67221.1 - 1.4e-05 25.4 0.3 0.071 13.6 0.1 3.1 3 0 0 3 3 3 2 CBS domain Aminotran_1_2 PF00155.21 KIY67222.1 - 9.9e-52 176.3 0.0 1.2e-41 143.1 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KIY67222.1 - 0.0043 16.4 0.0 0.0064 15.8 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase OKR_DC_1 PF01276.20 KIY67222.1 - 0.0062 15.3 0.0 0.012 14.4 0.0 1.3 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain zf-RVT PF13966.6 KIY67223.1 - 0.016 15.9 0.8 0.025 15.3 0.8 1.3 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase CpXC PF14353.6 KIY67223.1 - 0.042 13.9 0.1 0.049 13.7 0.1 1.1 1 0 0 1 1 1 0 CpXC protein Aminotran_3 PF00202.21 KIY67224.1 - 1.3e-111 373.1 0.0 1.6e-111 372.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KIY67224.1 - 3e-05 23.4 0.0 4.2e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KIY67224.1 - 0.00096 18.5 0.0 0.0016 17.8 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase GST_N_3 PF13417.6 KIY67226.1 - 5.1e-12 46.0 0.1 1.2e-11 44.8 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KIY67226.1 - 5.8e-10 39.3 0.0 9.5e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KIY67226.1 - 6.5e-05 22.9 0.4 0.00015 21.7 0.1 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KIY67226.1 - 0.0011 19.2 0.0 0.0022 18.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KIY67226.1 - 0.0072 16.5 0.0 0.018 15.2 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 KIY67226.1 - 0.015 15.6 0.0 0.025 14.9 0.0 1.3 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein GST_N_3 PF13417.6 KIY67227.1 - 5.3e-13 49.2 0.1 1.4e-12 47.9 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KIY67227.1 - 6.6e-11 42.4 0.0 1.5e-10 41.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KIY67227.1 - 1.6e-06 28.1 1.5 1.8e-06 27.9 0.4 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KIY67227.1 - 3.9e-06 27.0 0.4 6.9e-06 26.2 0.1 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KIY67227.1 - 0.0084 16.8 0.1 0.42 11.4 0.0 2.7 2 1 1 3 3 3 1 Glutathione S-transferase N-terminal domain GST_C_3 PF14497.6 KIY67227.1 - 0.019 15.1 0.0 0.053 13.7 0.0 1.8 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Plasmod_MYXSPDY PF07981.11 KIY67227.1 - 0.066 13.2 0.2 0.15 12.1 0.2 1.6 1 0 0 1 1 1 0 Plasmodium repeat_MYXSPDY GST_N PF02798.20 KIY67227.1 - 0.098 13.0 0.1 1.5 9.2 0.0 2.8 2 1 0 2 2 2 0 Glutathione S-transferase, N-terminal domain zf-MYND PF01753.18 KIY67228.1 - 1.4e-05 25.1 11.7 2.3e-05 24.4 11.7 1.3 1 0 0 1 1 1 1 MYND finger HLH PF00010.26 KIY67229.1 - 1.3e-08 34.7 0.0 2.9e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PKcGMP_CC PF16808.5 KIY67229.1 - 0.035 14.0 0.5 0.062 13.2 0.5 1.3 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase AAA_12 PF13087.6 KIY67230.1 - 1.9e-44 151.7 0.0 3.3e-44 150.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KIY67230.1 - 3.5e-27 95.8 0.0 3e-13 50.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KIY67230.1 - 4.4e-14 52.6 0.0 1.2e-13 51.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KIY67230.1 - 1.9e-10 41.3 0.0 1.1e-09 38.8 0.0 2.3 2 1 0 2 2 1 1 AAA domain PhoH PF02562.16 KIY67230.1 - 8.7e-05 22.1 0.0 0.0011 18.5 0.0 2.2 1 1 0 1 1 1 1 PhoH-like protein ResIII PF04851.15 KIY67230.1 - 0.00018 21.6 0.0 0.00042 20.4 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 KIY67230.1 - 0.00024 20.7 0.0 0.0013 18.3 0.0 2.0 1 1 1 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 KIY67230.1 - 0.003 17.8 0.0 0.027 14.8 0.0 2.5 1 1 1 2 2 2 1 AAA domain T2SSE PF00437.20 KIY67230.1 - 0.029 13.5 0.0 0.059 12.4 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Mg_chelatase PF01078.21 KIY67230.1 - 0.095 12.1 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF2075 PF09848.9 KIY67230.1 - 0.11 11.7 0.0 0.24 10.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.6 KIY67230.1 - 0.14 12.5 0.0 0.3 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 KIY67230.1 - 0.16 12.4 0.0 0.42 11.0 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) zf-C2H2_4 PF13894.6 KIY67230.1 - 0.26 12.2 1.3 0.78 10.8 1.3 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger zf-Di19 PF05605.12 KIY67230.1 - 0.8 10.1 4.9 0.41 11.0 0.9 2.5 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Catalase PF00199.19 KIY67231.1 - 1.7e-185 616.6 0.0 2.1e-185 616.3 0.0 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 KIY67231.1 - 1e-17 64.1 0.1 2.5e-17 62.8 0.1 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive p450 PF00067.22 KIY67232.1 - 6.8e-60 203.1 0.0 8.6e-60 202.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.7 KIY67234.1 - 7.8e-08 32.1 1.0 7.8e-08 32.1 1.0 2.0 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 KIY67235.1 - 1.5e-07 31.2 0.0 4.2e-07 29.7 0.0 1.9 1 1 0 1 1 1 1 F-box-like LRR_8 PF13855.6 KIY67235.1 - 0.027 14.2 0.1 2.5 8.0 0.1 2.5 2 0 0 2 2 2 0 Leucine rich repeat F-box PF00646.33 KIY67235.1 - 0.055 13.4 0.2 3.4 7.7 0.0 2.6 2 0 0 2 2 2 0 F-box domain adh_short PF00106.25 KIY67236.1 - 1.9e-33 115.6 0.1 3.2e-33 114.8 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIY67236.1 - 5.1e-30 104.8 0.0 7.8e-30 104.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIY67236.1 - 7.6e-06 26.0 2.0 2.8e-05 24.1 0.4 2.2 1 1 1 2 2 2 1 KR domain FAD_binding_4 PF01565.23 KIY67237.1 - 3.5e-26 91.6 3.8 5.9e-26 90.9 3.8 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KIY67237.1 - 0.00021 21.3 0.7 0.00038 20.5 0.1 1.8 2 0 0 2 2 2 1 Berberine and berberine like SUI1 PF01253.22 KIY67241.1 - 4.8e-25 87.9 0.7 9.1e-25 87.0 0.7 1.4 1 0 0 1 1 1 1 Translation initiation factor SUI1 Img2 PF05046.14 KIY67241.1 - 0.063 13.6 0.3 0.15 12.3 0.3 1.7 1 0 0 1 1 1 0 Mitochondrial large subunit ribosomal protein (Img2) CYSTM PF12734.7 KIY67242.1 - 0.00052 20.3 16.3 0.00052 20.3 16.3 3.3 2 2 0 2 2 2 1 Cysteine-rich TM module stress tolerance F-box-like PF12937.7 KIY67243.1 - 0.00055 19.8 0.7 0.0017 18.2 0.0 2.3 3 0 0 3 3 3 1 F-box-like M157 PF11624.8 KIY67243.1 - 0.046 13.1 0.0 0.085 12.2 0.0 1.4 1 0 0 1 1 1 0 MHC class I-like protein M157 DUF3760 PF12586.8 KIY67243.1 - 0.084 13.1 0.5 0.37 11.0 0.5 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3760) DUF913 PF06025.12 KIY67243.1 - 0.22 10.5 0.5 0.41 9.6 0.1 1.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) NmrA PF05368.13 KIY67245.1 - 1e-43 149.6 0.3 1.3e-43 149.2 0.3 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KIY67245.1 - 6.5e-15 55.5 0.1 1e-14 54.9 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KIY67245.1 - 3.7e-06 26.6 0.1 7.8e-06 25.5 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family CbiJ PF02571.14 KIY67245.1 - 0.096 12.1 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Precorrin-6x reductase CbiJ/CobK 3Beta_HSD PF01073.19 KIY67245.1 - 0.12 11.4 0.0 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Abhydrolase_6 PF12697.7 KIY67246.1 - 0.0042 17.7 0.9 0.0064 17.1 0.3 1.7 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 KIY67246.1 - 0.0098 15.7 0.0 0.024 14.4 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 KIY67246.1 - 0.02 14.6 0.0 0.031 14.0 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Thioesterase PF00975.20 KIY67246.1 - 0.02 15.0 0.0 0.035 14.2 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Chlorophyllase2 PF12740.7 KIY67246.1 - 0.04 12.8 0.0 0.059 12.3 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Hydrolase_4 PF12146.8 KIY67246.1 - 0.091 12.0 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF1749 PF08538.10 KIY67246.1 - 0.13 11.3 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) DUF2974 PF11187.8 KIY67246.1 - 0.13 11.8 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) RicinB_lectin_2 PF14200.6 KIY67247.1 - 1.1e-09 38.9 4.6 1.7e-07 31.8 0.3 2.4 1 1 2 3 3 3 3 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 KIY67247.1 - 0.025 14.8 0.3 2.4 8.4 0.0 2.3 1 1 1 2 2 2 0 Ricin-type beta-trefoil lectin domain adh_short_C2 PF13561.6 KIY67248.1 - 4e-32 111.6 0.4 6.7e-32 110.9 0.4 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIY67248.1 - 3.9e-31 108.0 0.3 5.6e-31 107.5 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIY67248.1 - 0.01 15.8 0.5 0.018 14.9 0.0 1.6 2 0 0 2 2 2 1 KR domain adh_short PF00106.25 KIY67249.1 - 0.017 14.6 0.1 0.032 13.7 0.1 1.5 1 1 0 1 1 1 0 short chain dehydrogenase Thioredoxin PF00085.20 KIY67249.1 - 0.076 13.0 0.0 0.097 12.7 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Iso_dh PF00180.20 KIY67250.1 - 2.4e-74 250.6 0.0 3e-74 250.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DHFR_2 PF06442.11 KIY67250.1 - 0.12 12.2 0.0 28 4.6 0.0 2.6 2 0 0 2 2 2 0 R67 dihydrofolate reductase Rbx_binding PF18113.1 KIY67250.1 - 0.15 11.9 0.0 0.37 10.6 0.0 1.6 1 0 0 1 1 1 0 Rubredoxin binding C-terminal domain UDPG_MGDP_dh_N PF03721.14 KIY67251.1 - 3.3e-61 206.1 0.0 5.8e-61 205.3 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.15 KIY67251.1 - 6.9e-34 116.4 0.1 3.3e-33 114.3 0.1 2.0 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.19 KIY67251.1 - 6.4e-31 106.4 0.0 1.3e-30 105.4 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain Sacchrp_dh_NADP PF03435.18 KIY67251.1 - 0.041 14.1 0.2 0.35 11.1 0.0 2.6 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 KIY67251.1 - 0.094 13.3 0.1 11 6.7 0.1 3.2 3 1 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent DJ-1_PfpI PF01965.24 KIY67252.1 - 4.6e-38 130.6 0.0 5.2e-38 130.4 0.0 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 KIY67252.1 - 0.028 14.1 0.0 0.049 13.3 0.0 1.4 1 0 0 1 1 1 0 ThiJ/PfpI family-like GATase_3 PF07685.14 KIY67252.1 - 0.035 13.7 0.0 0.048 13.3 0.0 1.1 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain RITA PF17066.5 KIY67252.1 - 0.056 13.0 0.0 0.08 12.5 0.0 1.2 1 0 0 1 1 1 0 RBPJ-interacting and tubulin associated protein Pkinase PF00069.25 KIY67253.1 - 7e-35 120.7 0.0 1e-34 120.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY67253.1 - 5.3e-33 114.4 0.0 6.9e-33 114.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Sec8_exocyst PF04048.14 KIY67255.1 - 0.037 13.9 1.0 0.06 13.2 1.0 1.3 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain TPR_MLP1_2 PF07926.12 KIY67255.1 - 1.7 8.7 13.7 1.2 9.2 12.2 1.5 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Thioredoxin_4 PF13462.6 KIY67255.1 - 4.5 7.4 7.3 4.3 7.5 5.3 1.8 1 1 1 2 2 2 0 Thioredoxin Pkinase PF00069.25 KIY67256.1 - 2.9e-57 194.0 0.0 4.9e-31 108.1 0.0 3.4 3 0 0 3 3 3 3 Protein kinase domain HGTP_anticodon2 PF12745.7 KIY67256.1 - 3.4e-27 95.6 1.5 6.8e-27 94.6 0.0 2.2 2 1 0 2 2 2 1 Anticodon binding domain of tRNAs Pkinase_Tyr PF07714.17 KIY67256.1 - 1.1e-26 93.7 0.0 9.5e-14 51.3 0.0 3.5 3 0 0 3 3 3 3 Protein tyrosine kinase RWD PF05773.22 KIY67256.1 - 1.6e-16 60.6 0.0 4.9e-16 59.1 0.0 1.9 1 0 0 1 1 1 1 RWD domain APH PF01636.23 KIY67256.1 - 0.0017 18.3 2.2 0.0036 17.3 0.0 2.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KIY67256.1 - 0.07 11.9 0.0 0.15 10.8 0.0 1.6 1 0 0 1 1 1 0 Fungal protein kinase FAM60A PF15396.6 KIY67256.1 - 0.12 12.4 0.4 20 5.1 0.1 3.1 3 0 0 3 3 3 0 Protein Family FAM60A CENP-N PF05238.13 KIY67256.1 - 0.12 11.6 0.5 0.9 8.8 0.0 2.0 2 0 0 2 2 2 0 Kinetochore protein CHL4 like Haspin_kinase PF12330.8 KIY67256.1 - 0.13 11.1 0.0 0.26 10.2 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Methyltransf_16 PF10294.9 KIY67257.1 - 1.4e-19 70.5 0.0 3.8e-19 69.1 0.0 1.6 1 1 1 2 2 2 1 Lysine methyltransferase Methyltransf_23 PF13489.6 KIY67257.1 - 0.00078 19.3 0.0 0.085 12.7 0.0 2.2 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 KIY67257.1 - 0.0078 16.9 0.0 0.025 15.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KIY67257.1 - 0.045 13.3 0.0 0.14 11.7 0.0 1.9 3 0 0 3 3 3 0 Methyltransferase small domain AAA_12 PF13087.6 KIY67258.1 - 9.6e-35 120.0 0.0 2.2e-34 118.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KIY67258.1 - 3.1e-20 73.1 0.1 5.7e-11 42.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KIY67258.1 - 1.2e-16 61.0 0.0 3.1e-16 59.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KIY67258.1 - 8.9e-14 52.1 0.1 3.6e-13 50.1 0.0 2.1 3 0 0 3 3 2 1 AAA domain Helicase_RecD PF05127.14 KIY67258.1 - 3.4e-05 23.8 0.0 9.1e-05 22.4 0.0 1.7 1 1 0 1 1 1 1 Helicase PhoH PF02562.16 KIY67258.1 - 0.00017 21.1 0.0 0.00044 19.8 0.0 1.7 1 0 0 1 1 1 1 PhoH-like protein AAA_16 PF13191.6 KIY67258.1 - 0.00029 21.3 0.0 0.00069 20.0 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain Herpes_ori_bp PF02399.15 KIY67258.1 - 0.00033 18.9 0.0 0.00054 18.2 0.0 1.2 1 0 0 1 1 1 1 Origin of replication binding protein DEAD PF00270.29 KIY67258.1 - 0.003 17.3 0.1 0.027 14.2 0.1 2.3 2 1 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 KIY67258.1 - 0.02 14.9 0.0 0.054 13.5 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA PF00004.29 KIY67258.1 - 0.043 14.2 0.0 0.21 12.0 0.0 2.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 KIY67258.1 - 0.082 12.1 0.3 0.35 10.1 0.1 2.1 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 KIY67258.1 - 0.089 13.1 0.0 0.7 10.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 KIY67258.1 - 0.11 12.3 0.5 22 4.7 0.0 3.0 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase AAA_12 PF13087.6 KIY67259.1 - 3.7e-34 118.1 0.0 2.8e-33 115.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KIY67259.1 - 1.2e-25 90.8 0.1 5.2e-12 46.1 0.0 2.6 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.6 KIY67259.1 - 3.7e-17 62.7 0.0 2e-16 60.3 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KIY67259.1 - 6.4e-13 49.3 0.0 2e-12 47.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KIY67259.1 - 2.8e-06 27.8 0.0 1.8e-05 25.2 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain ResIII PF04851.15 KIY67259.1 - 6.6e-06 26.2 0.0 1.2e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 KIY67259.1 - 9.6e-06 25.5 0.0 0.22 11.3 0.0 3.2 2 1 0 2 2 2 2 Viral (Superfamily 1) RNA helicase PhoH PF02562.16 KIY67259.1 - 1e-05 25.1 0.0 0.00014 21.4 0.0 2.2 1 1 0 1 1 1 1 PhoH-like protein DUF2075 PF09848.9 KIY67259.1 - 5e-05 22.7 0.0 0.022 14.0 0.0 3.1 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.14 KIY67259.1 - 9e-05 22.4 0.0 0.00034 20.5 0.0 2.0 1 1 0 1 1 1 1 Helicase IstB_IS21 PF01695.17 KIY67259.1 - 0.00097 18.9 0.0 0.0031 17.2 0.0 1.8 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_22 PF13401.6 KIY67259.1 - 0.0012 19.1 0.1 0.0069 16.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain DEAD PF00270.29 KIY67259.1 - 0.0014 18.4 0.0 0.0034 17.2 0.0 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA PF00004.29 KIY67259.1 - 0.0037 17.7 0.0 0.0091 16.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KIY67259.1 - 0.0052 16.0 0.0 0.0089 15.2 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_28 PF13521.6 KIY67259.1 - 0.016 15.5 0.1 0.048 13.9 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_18 PF13238.6 KIY67259.1 - 0.022 15.3 0.0 0.099 13.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain PPV_E1_C PF00519.17 KIY67259.1 - 0.027 13.3 0.0 0.043 12.7 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase NTPase_1 PF03266.15 KIY67259.1 - 0.041 13.8 2.0 1.2 9.1 0.1 3.7 4 0 0 4 4 4 0 NTPase T2SSE PF00437.20 KIY67259.1 - 0.044 12.9 0.0 0.073 12.1 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_25 PF13481.6 KIY67259.1 - 0.044 13.4 0.0 0.092 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KIY67259.1 - 0.051 13.7 0.0 0.18 12.0 0.0 2.0 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 KIY67259.1 - 0.073 12.5 0.0 3.3 7.1 0.0 2.4 2 0 0 2 2 2 0 Bacterial TniB protein AAA_23 PF13476.6 KIY67259.1 - 0.091 13.3 0.1 0.21 12.1 0.0 1.7 2 0 0 2 2 1 0 AAA domain NACHT PF05729.12 KIY67259.1 - 0.094 12.6 0.2 2.3 8.1 0.0 3.1 3 1 1 4 4 4 0 NACHT domain MeaB PF03308.16 KIY67259.1 - 0.11 11.5 0.0 0.41 9.6 0.0 1.9 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 KIY67259.1 - 0.12 12.1 0.4 0.23 11.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain DAP3 PF10236.9 KIY67259.1 - 0.14 11.3 0.0 0.32 10.1 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 ATPase PF06745.13 KIY67259.1 - 0.15 11.3 0.0 0.41 10.0 0.0 1.6 2 0 0 2 2 2 0 KaiC UvrD-helicase PF00580.21 KIY67259.1 - 0.18 11.3 0.0 0.52 9.8 0.0 1.8 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain XPG_N PF00752.17 KIY67260.1 - 9.4e-30 103.1 0.0 2.1e-29 101.9 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 KIY67260.1 - 1.2e-25 89.7 0.0 3.2e-25 88.3 0.0 1.8 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.7 KIY67260.1 - 0.00025 20.6 0.0 0.00063 19.3 0.0 1.7 1 0 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.20 KIY67260.1 - 0.014 15.9 0.1 0.13 12.9 0.0 2.6 4 0 0 4 4 4 0 5'-3' exonuclease, C-terminal SAM fold NDUF_B8 PF05821.11 KIY67261.1 - 0.054 13.4 0.7 0.089 12.7 0.7 1.3 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) Methyltransf_25 PF13649.6 KIY67262.1 - 1.2e-12 48.3 0.0 2.5e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIY67262.1 - 4.2e-09 36.5 0.0 7.4e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIY67262.1 - 1.9e-08 34.8 0.0 4.3e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIY67262.1 - 6.7e-07 28.9 0.0 1.1e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KIY67262.1 - 1.2e-05 25.1 0.0 2.3e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KIY67262.1 - 0.002 18.3 0.0 0.0042 17.2 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_2 PF00891.18 KIY67262.1 - 0.0047 16.2 0.0 0.0076 15.6 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_12 PF08242.12 KIY67262.1 - 0.011 16.5 0.0 0.021 15.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KIY67262.1 - 0.042 13.4 0.0 0.093 12.3 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_4 PF02390.17 KIY67262.1 - 0.05 13.1 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase PrmA PF06325.13 KIY67262.1 - 0.18 11.1 0.0 0.32 10.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) COesterase PF00135.28 KIY67263.1 - 4e-60 204.1 0.0 5.3e-60 203.7 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KIY67263.1 - 1.1e-07 31.9 0.1 5.2e-07 29.7 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KIY67264.1 - 3.4e-20 72.4 0.0 3.7e-20 72.3 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Pec_lyase_C PF00544.19 KIY67265.1 - 3.5e-39 134.6 9.2 5.4e-39 134.0 9.2 1.2 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 KIY67265.1 - 1.7e-05 24.7 12.2 5.7e-05 23.0 12.2 1.8 1 1 0 1 1 1 1 Right handed beta helix region MRVI1 PF05781.12 KIY67266.1 - 0.11 11.2 4.1 0.26 9.9 4.1 1.6 1 1 0 1 1 1 0 MRVI1 protein Metallophos PF00149.28 KIY67267.1 - 1.1e-35 124.0 0.6 1.5e-35 123.6 0.6 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KIY67267.1 - 0.0034 17.8 0.2 0.0066 16.9 0.2 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Glyco_hydro_65N PF03636.15 KIY67267.1 - 0.029 14.0 0.0 0.048 13.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain Cpn60_TCP1 PF00118.24 KIY67268.1 - 2.2e-153 511.5 1.9 2.5e-153 511.3 1.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Kisspeptin PF15152.6 KIY67269.1 - 0.13 13.1 2.3 0.14 13.0 0.6 1.9 1 1 1 2 2 2 0 Kisspeptin Methyltransf_31 PF13847.6 KIY67270.1 - 4.5e-15 55.8 0.0 6.9e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIY67270.1 - 1.4e-06 28.9 0.1 8e-06 26.5 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIY67270.1 - 8.9e-06 26.4 0.0 1.8e-05 25.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIY67270.1 - 2e-05 24.5 0.0 9.1e-05 22.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIY67270.1 - 0.00013 22.5 0.0 0.01 16.5 0.0 2.9 3 0 0 3 3 3 1 Methyltransferase domain MTS PF05175.14 KIY67270.1 - 0.00027 20.5 0.0 0.00082 19.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_32 PF13679.6 KIY67270.1 - 0.01 15.8 0.0 0.014 15.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 KIY67270.1 - 0.011 15.0 0.0 0.17 11.2 0.0 2.0 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase PCMT PF01135.19 KIY67270.1 - 0.046 13.5 0.0 0.063 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DnaJ PF00226.31 KIY67271.1 - 0.0057 16.8 0.0 0.0076 16.3 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.13 KIY67271.1 - 0.0086 16.1 0.0 0.01 15.9 0.0 1.1 1 0 0 1 1 1 1 Pam16 Dyp_perox PF04261.12 KIY67271.1 - 0.047 12.7 0.0 0.052 12.5 0.0 1.1 1 0 0 1 1 1 0 Dyp-type peroxidase family DUF3808 PF10300.9 KIY67272.1 - 3.6e-62 210.7 0.4 1.2e-60 205.7 0.4 2.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_16 PF13432.6 KIY67272.1 - 1.8e-05 25.3 1.4 0.4 11.4 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KIY67272.1 - 0.051 13.7 5.2 1.1 9.5 0.6 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 KIY67272.1 - 0.07 13.2 0.2 18 5.7 0.0 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 KIY67272.1 - 0.17 12.2 4.7 4.3 7.7 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Piwi PF02171.17 KIY67273.1 - 3.6e-68 230.0 0.0 1.2e-64 218.5 0.0 3.0 2 1 0 2 2 2 2 Piwi domain ArgoL1 PF08699.10 KIY67273.1 - 1e-12 47.5 0.0 2.6e-12 46.2 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoMid PF16487.5 KIY67273.1 - 2.2e-11 43.8 0.1 6e-11 42.5 0.1 1.8 1 0 0 1 1 1 1 Mid domain of argonaute ArgoN PF16486.5 KIY67273.1 - 4.1e-09 37.2 0.0 1.1e-08 35.8 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL2 PF16488.5 KIY67273.1 - 2.1e-06 27.9 0.0 1.2e-05 25.6 0.0 2.3 2 0 0 2 2 2 1 Argonaute linker 2 domain PH PF00169.29 KIY67274.1 - 3.8e-05 24.1 0.0 0.00027 21.4 0.0 2.3 2 0 0 2 2 2 1 PH domain PH_9 PF15410.6 KIY67274.1 - 0.08 13.3 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain OST_IS PF18246.1 KIY67274.1 - 0.12 12.7 0.1 0.27 11.5 0.1 1.5 1 0 0 1 1 1 0 Oligosaccharyltransferase Insert domain NOA36 PF06524.12 KIY67274.1 - 4.4 6.5 7.2 9.2 5.5 7.2 1.4 1 0 0 1 1 1 0 NOA36 protein Citrate_synt PF00285.21 KIY67275.1 - 3.4e-100 335.6 0.0 4.4e-100 335.2 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain SAP130_C PF16014.5 KIY67276.1 - 7.9 5.4 10.3 9.2 5.2 10.3 1.1 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus Pcc1 PF09341.10 KIY67277.1 - 6.3e-25 87.1 0.4 7.2e-25 86.9 0.4 1.0 1 0 0 1 1 1 1 Transcription factor Pcc1 Peptidase_M24 PF00557.24 KIY67278.1 - 2.8e-15 56.6 0.1 4.7e-15 55.9 0.1 1.4 1 1 0 1 1 1 1 Metallopeptidase family M24 GPI-anchored PF10342.9 KIY67279.1 - 1.2e-05 25.9 0.2 1.2e-05 25.9 0.2 2.2 1 1 1 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4971 PF16341.5 KIY67279.1 - 1.8 8.4 4.7 2.2 8.1 0.2 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4971) Abhydrolase_1 PF00561.20 KIY67280.1 - 2e-18 67.0 0.0 3.4e-17 63.0 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIY67280.1 - 1.2e-08 34.5 0.0 0.00095 18.5 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KIY67280.1 - 1.7e-08 35.4 0.1 2.2e-08 35.0 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KIY67280.1 - 0.00027 20.5 0.0 0.00041 19.9 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 KIY67280.1 - 0.0098 15.6 0.0 0.023 14.3 0.0 1.6 1 0 0 1 1 1 1 Putative esterase DUF2920 PF11144.8 KIY67280.1 - 0.028 13.6 0.0 0.052 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Ser_hydrolase PF06821.13 KIY67280.1 - 0.03 14.2 0.1 0.057 13.3 0.1 1.4 1 0 0 1 1 1 0 Serine hydrolase Abhydrolase_2 PF02230.16 KIY67280.1 - 0.046 13.5 0.0 1.8 8.3 0.0 2.4 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 KIY67281.1 - 6.6e-33 114.4 0.0 8.5e-33 114.1 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIY67281.1 - 3.6e-10 40.8 0.1 5.3e-10 40.3 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIY67281.1 - 3.9e-10 39.4 0.0 1.5e-09 37.5 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 FGGY_C PF02782.16 KIY67282.1 - 2.8e-44 151.3 0.0 3.9e-44 150.8 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KIY67282.1 - 1.1e-20 74.2 0.1 7.4e-20 71.6 0.1 2.3 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Hexokinase_1 PF00349.21 KIY67282.1 - 0.052 13.4 0.0 0.089 12.7 0.0 1.4 1 0 0 1 1 1 0 Hexokinase BcrAD_BadFG PF01869.20 KIY67282.1 - 0.083 12.4 0.2 0.78 9.2 0.0 2.2 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Mitofilin PF09731.9 KIY67283.1 - 4.3e-26 92.0 2.2 4.6e-26 91.9 2.2 1.0 1 0 0 1 1 1 1 Mitochondrial inner membrane protein ArnB_C PF18677.1 KIY67283.1 - 0.012 15.7 0.6 0.014 15.5 0.6 1.2 1 1 0 1 1 1 0 Archaellum regulatory network B, C-terminal domain Hpt PF01627.23 KIY67283.1 - 0.013 15.8 0.1 0.016 15.4 0.1 1.2 1 0 0 1 1 1 0 Hpt domain LPD39 PF18858.1 KIY67283.1 - 0.014 15.5 0.4 0.016 15.3 0.4 1.0 1 0 0 1 1 1 0 Large polyvalent protein associated domain 39 GCN5L1 PF06320.13 KIY67283.1 - 0.042 14.0 0.2 0.055 13.6 0.1 1.3 1 1 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) AMP-binding PF00501.28 KIY67284.1 - 1.5e-82 277.5 0.0 1.9e-82 277.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KIY67284.1 - 2.4e-11 44.4 1.7 4.1e-11 43.7 0.9 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Pkinase PF00069.25 KIY67285.1 - 2.1e-55 188.0 0.0 2.5e-55 187.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY67285.1 - 3.4e-33 115.0 0.0 4.1e-33 114.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY67285.1 - 6.9e-05 22.3 0.0 0.00011 21.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KIY67285.1 - 0.00028 19.8 0.0 0.00028 19.8 0.0 1.2 1 1 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KIY67285.1 - 0.01 15.2 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KIY67285.1 - 0.012 15.3 0.0 0.038 13.6 0.0 1.8 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Seadorna_VP7 PF07387.11 KIY67285.1 - 0.082 11.9 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 YrbL-PhoP_reg PF10707.9 KIY67285.1 - 0.2 11.2 0.0 0.33 10.4 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL E1_dh PF00676.20 KIY67286.1 - 2.1e-110 368.4 0.0 2.6e-110 368.1 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 KIY67286.1 - 7.1e-06 25.4 0.1 1.6e-05 24.3 0.0 1.5 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 KIY67286.1 - 0.0012 18.7 0.6 0.0012 18.7 0.6 1.6 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain NYN PF01936.18 KIY67287.1 - 2e-11 44.6 0.0 2.6e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 NYN domain GreA_GreB_N PF03449.15 KIY67290.1 - 0.046 13.9 0.9 0.2 11.9 0.1 2.2 2 0 0 2 2 2 0 Transcription elongation factor, N-terminal DUF1993 PF09351.10 KIY67290.1 - 0.11 12.7 0.8 0.65 10.1 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF1993) Sec2p PF06428.11 KIY67290.1 - 0.11 12.5 1.1 0.25 11.4 1.1 1.5 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p Striatin PF08232.12 KIY67290.1 - 0.12 13.0 3.3 0.23 12.0 3.3 1.5 1 0 0 1 1 1 0 Striatin family DUF2333 PF10095.9 KIY67290.1 - 0.15 11.0 1.8 0.24 10.4 1.8 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2333) RFamide_26RFa PF11109.8 KIY67290.1 - 0.16 12.5 1.9 0.47 11.0 1.9 1.8 1 0 0 1 1 1 0 Orexigenic neuropeptide Qrfp/P518 Spc7 PF08317.11 KIY67290.1 - 0.2 10.5 3.4 0.24 10.2 1.2 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein Uds1 PF15456.6 KIY67290.1 - 1.2 9.3 11.3 1.1 9.4 8.1 2.6 2 1 0 2 2 2 0 Up-regulated During Septation T2SSM PF04612.12 KIY67290.1 - 2.6 8.1 6.4 0.56 10.3 0.7 2.4 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M DUF1347 PF07079.11 KIY67291.1 - 0.02 13.5 0.3 0.034 12.7 0.2 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1347) GPHR_N PF12537.8 KIY67291.1 - 0.61 10.2 0.1 0.61 10.2 0.1 2.5 3 0 0 3 3 3 0 The Golgi pH Regulator (GPHR) Family N-terminal COX4_pro PF03626.14 KIY67292.1 - 0.17 12.3 0.3 0.17 12.3 0.3 2.7 2 0 0 2 2 2 0 Prokaryotic Cytochrome C oxidase subunit IV Collagen PF01391.18 KIY67294.1 - 0.031 14.0 4.6 0.068 12.9 4.6 1.4 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) Rgp1 PF08737.10 KIY67296.1 - 2.6e-49 168.5 0.0 6.8e-49 167.2 0.0 1.8 2 0 0 2 2 2 1 Rgp1 Arrestin_C PF02752.22 KIY67296.1 - 1.1e-06 29.1 0.1 0.058 13.8 0.0 3.5 3 0 0 3 3 3 3 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KIY67296.1 - 0.00043 20.3 0.0 0.13 12.3 0.0 3.0 2 1 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Dicty_CAR PF05462.11 KIY67297.1 - 0.022 13.9 0.3 0.23 10.6 0.0 2.2 1 1 1 2 2 2 0 Slime mold cyclic AMP receptor DUF3318 PF11780.8 KIY67297.1 - 0.022 14.7 2.5 0.038 13.9 2.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3318) CitMHS PF03600.16 KIY67297.1 - 7.5 5.6 12.0 9.4 5.3 12.0 1.1 1 0 0 1 1 1 0 Citrate transporter Nop16 PF09420.10 KIY67298.1 - 0.032 14.3 1.3 0.041 13.9 1.3 1.3 1 0 0 1 1 1 0 Ribosome biogenesis protein Nop16 SDA1 PF05285.12 KIY67298.1 - 0.16 11.3 6.6 0.21 11.0 6.6 1.1 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 KIY67298.1 - 3.8 5.5 8.6 4.2 5.3 8.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 KIY67298.1 - 9.7 4.3 7.2 12 4.1 7.2 1.0 1 0 0 1 1 1 0 CDC45-like protein ATG16 PF08614.11 KIY67299.1 - 0.0073 16.6 1.5 0.0073 16.6 1.5 2.9 3 1 1 4 4 4 1 Autophagy protein 16 (ATG16) GIT_CC PF16559.5 KIY67299.1 - 0.15 11.9 0.8 0.31 10.9 0.8 1.5 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor DivIC PF04977.15 KIY67299.1 - 1.1 9.1 3.0 0.77 9.6 0.3 2.1 2 0 0 2 2 2 0 Septum formation initiator Forkhead PF00250.18 KIY67301.1 - 0.0014 18.8 0.0 0.0016 18.6 0.0 1.1 1 0 0 1 1 1 1 Forkhead domain Exo_endo_phos PF03372.23 KIY67302.1 - 4.1e-08 33.0 0.0 5.2e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DAO PF01266.24 KIY67303.1 - 2e-16 60.6 0.0 2.3e-16 60.4 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_4 PF07993.12 KIY67304.1 - 9.7e-35 120.0 0.0 2.1e-34 118.9 0.0 1.6 2 0 0 2 2 2 1 Male sterility protein AMP-binding PF00501.28 KIY67304.1 - 2.3e-27 95.7 0.0 5.4e-27 94.4 0.0 1.7 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 KIY67304.1 - 1.4e-10 41.0 0.0 4.3e-10 39.5 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KIY67304.1 - 1.8e-09 37.8 0.0 5.2e-09 36.3 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site KR PF08659.10 KIY67304.1 - 0.00058 19.8 0.0 0.0011 19.0 0.0 1.5 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KIY67304.1 - 0.007 15.5 0.1 0.013 14.7 0.1 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 KIY67304.1 - 0.031 14.6 0.1 3.4 7.9 0.1 3.1 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 KIY67304.1 - 0.19 12.2 0.2 5.2 7.5 0.1 3.0 3 0 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain DAO PF01266.24 KIY67306.1 - 8.5e-25 88.1 0.0 1e-24 87.8 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIY67306.1 - 3e-05 23.4 0.0 0.00012 21.4 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KIY67306.1 - 7.3e-05 23.2 0.0 0.00015 22.2 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding NAD_binding_8 PF13450.6 KIY67306.1 - 0.00052 20.2 0.1 0.0016 18.6 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KIY67306.1 - 0.0015 17.8 0.0 0.0028 16.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 KIY67306.1 - 0.0065 17.0 0.5 0.019 15.5 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KIY67306.1 - 0.0073 15.6 0.0 0.017 14.4 0.0 1.5 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 KIY67306.1 - 0.014 14.7 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KIY67306.1 - 0.016 14.3 0.0 0.047 12.8 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.22 KIY67306.1 - 0.018 14.2 0.0 0.037 13.1 0.0 1.5 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 KIY67306.1 - 0.13 11.6 0.3 1.8 7.8 0.1 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase ApbA PF02558.16 KIY67306.1 - 0.13 11.9 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA PRP3 PF08572.10 KIY67308.1 - 1.3e-67 227.8 4.4 1.3e-67 227.8 4.4 1.8 2 0 0 2 2 2 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 KIY67308.1 - 2.3e-42 144.5 0.7 5.2e-42 143.4 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) ESM4 PF15952.5 KIY67308.1 - 0.088 13.2 0.6 0.24 11.8 0.6 1.7 1 0 0 1 1 1 0 Enhancer of split M4 family Peptidase_M20 PF01546.28 KIY67309.1 - 5.8e-30 104.5 0.1 8.6e-30 104.0 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KIY67309.1 - 2e-11 43.8 0.0 5.7e-11 42.3 0.0 1.9 1 1 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KIY67309.1 - 7.7e-05 22.5 0.1 0.00024 20.8 0.1 1.7 1 1 0 1 1 1 1 Peptidase family M28 zf-H2C2_2 PF13465.6 KIY67310.1 - 1.3e-24 85.5 34.2 5.9e-07 29.6 0.5 6.6 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2 PF00096.26 KIY67310.1 - 1.2e-22 79.0 49.6 1.2e-05 25.5 1.3 8.4 9 0 0 9 9 9 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIY67310.1 - 1.2e-18 66.1 44.1 0.00019 22.0 1.2 8.0 8 0 0 8 8 8 5 C2H2-type zinc finger FOXP-CC PF16159.5 KIY67310.1 - 5.2e-08 33.4 38.0 0.022 15.4 0.8 7.7 4 2 3 7 7 7 3 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 KIY67310.1 - 1.2e-05 25.5 17.9 0.035 14.4 1.3 4.3 2 1 1 4 4 4 2 C2H2-type zinc ribbon zf-C2H2_11 PF16622.5 KIY67310.1 - 2.8e-05 23.8 23.4 0.029 14.1 0.4 5.9 6 0 0 6 6 6 3 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 KIY67310.1 - 0.00031 21.0 17.9 0.63 10.4 0.5 4.4 3 2 0 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2H2_3rep PF18868.1 KIY67310.1 - 0.0052 17.5 12.7 3.7 8.2 0.0 4.8 2 2 1 5 5 5 1 Zinc finger C2H2-type, 3 repeats zf-C2H2_jaz PF12171.8 KIY67310.1 - 0.0069 16.7 17.8 0.021 15.1 0.4 4.6 6 0 0 6 6 5 2 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KIY67310.1 - 0.01 15.6 3.8 0.01 15.6 3.8 6.9 7 1 0 7 7 7 0 C2H2-type zinc-finger domain zf-C2HE PF16278.5 KIY67310.1 - 0.044 14.2 0.4 0.044 14.2 0.4 3.8 4 1 0 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_6 PF13912.6 KIY67310.1 - 0.12 12.4 27.0 0.23 11.5 1.5 6.1 6 0 0 6 6 6 0 C2H2-type zinc finger PyrI_C PF02748.15 KIY67310.1 - 0.14 12.1 5.1 0.16 11.9 0.3 2.8 2 1 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf_C2H2_ZHX PF18387.1 KIY67310.1 - 1.2 8.9 15.9 7.4 6.3 1.0 4.5 4 0 0 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_9 PF16293.5 KIY67310.1 - 1.4 8.8 7.6 65 3.5 0.0 4.4 4 0 0 4 4 4 0 C2H2 type zinc-finger (1 copy) MCM_OB PF17207.3 KIY67310.1 - 8 6.3 11.5 3.8 7.4 2.4 2.8 1 1 2 3 3 3 0 MCM OB domain Zf_RING PF16744.5 KIY67310.1 - 8.1 6.6 11.0 2.4 8.3 1.0 3.4 3 0 0 3 3 3 0 KIAA1045 RING finger C1_4 PF07975.12 KIY67310.1 - 9.2 6.6 14.3 0.37 11.1 1.8 3.7 2 1 2 4 4 4 0 TFIIH C1-like domain adh_short PF00106.25 KIY67311.1 - 1.8e-50 171.1 0.8 2.3e-50 170.8 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIY67311.1 - 1e-49 169.2 0.4 1.3e-49 168.9 0.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIY67311.1 - 5.3e-09 36.2 0.5 5.3e-09 36.2 0.5 1.6 2 0 0 2 2 2 1 KR domain THF_DHG_CYH_C PF02882.19 KIY67311.1 - 0.12 11.7 0.1 0.63 9.3 0.0 2.0 1 1 1 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain P34-Arc PF04045.14 KIY67312.1 - 1.3e-110 368.8 0.1 1.6e-110 368.5 0.1 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc Transferase PF02458.15 KIY67313.1 - 8.7e-35 120.2 0.0 6.7e-29 100.8 0.0 3.1 2 1 0 2 2 2 2 Transferase family DNA_ligase_A_M PF01068.21 KIY67314.1 - 4.1e-51 173.5 0.1 6.7e-51 172.8 0.1 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KIY67314.1 - 2.5e-41 141.9 1.0 3.3e-41 141.5 0.1 1.7 2 0 0 2 2 2 1 DNA ligase N terminus BRCT_2 PF16589.5 KIY67314.1 - 4.9e-18 65.3 0.1 5.4e-08 33.1 0.1 3.1 2 1 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain RNA_ligase PF09414.10 KIY67314.1 - 1.2e-13 51.7 0.5 2.2e-13 50.8 0.1 1.7 2 0 0 2 2 2 1 RNA ligase DNA_ligase_A_C PF04679.15 KIY67314.1 - 1.9e-13 50.8 0.0 1.7e-12 47.8 0.0 2.7 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region BRCT PF00533.26 KIY67314.1 - 2.7e-05 24.4 0.1 0.04 14.3 0.0 3.1 2 1 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain Inovirus_Gp2 PF11726.8 KIY67314.1 - 0.038 14.0 0.5 0.14 12.1 0.1 2.1 3 0 0 3 3 3 0 Inovirus Gp2 Pkinase PF00069.25 KIY67315.1 - 5.3e-66 222.7 0.0 9.8e-66 221.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY67315.1 - 3.1e-36 125.0 0.0 5.6e-36 124.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY67315.1 - 0.00015 21.2 0.0 0.00027 20.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KIY67315.1 - 0.004 16.5 0.1 0.0069 15.8 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIY67315.1 - 0.0054 16.7 0.6 0.027 14.4 0.0 2.3 2 1 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KIY67315.1 - 0.0063 15.5 0.7 0.011 14.7 0.0 1.6 2 0 0 2 2 2 1 Haspin like kinase domain Fungal_KA1 PF16797.5 KIY67315.1 - 0.0084 15.8 0.1 0.019 14.7 0.1 1.5 1 0 0 1 1 1 1 Fungal kinase associated-1 domain RIO1 PF01163.22 KIY67315.1 - 0.039 13.6 0.4 0.6 9.7 0.0 2.2 1 1 1 2 2 2 0 RIO1 family Forkhead PF00250.18 KIY67316.1 - 6.4e-23 80.8 0.1 1.3e-22 79.9 0.1 1.5 1 0 0 1 1 1 1 Forkhead domain Palm_thioest PF02089.15 KIY67317.1 - 1.6e-81 273.7 0.0 2.4e-81 273.2 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 KIY67317.1 - 0.011 15.4 0.1 0.024 14.3 0.1 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold Amidohydro_1 PF01979.20 KIY67319.1 - 4.8e-13 49.1 0.0 2e-10 40.5 0.0 2.5 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 KIY67319.1 - 5.6e-12 45.9 4.4 1.8e-07 31.0 0.0 3.0 3 0 0 3 3 3 2 Amidohydrolase family HhH-GPD PF00730.25 KIY67321.1 - 3e-11 43.7 0.0 4.3e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KIY67321.1 - 0.011 15.6 0.0 0.035 14.0 0.0 1.8 2 0 0 2 2 2 0 Helix-hairpin-helix motif HMG_box PF00505.19 KIY67322.1 - 1.2e-09 38.4 7.4 1.3e-08 35.1 7.4 2.2 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KIY67322.1 - 1.1e-08 35.5 2.5 2.8e-08 34.2 2.5 1.6 1 0 0 1 1 1 1 HMG-box domain Methyltransf_22 PF13383.6 KIY67323.1 - 1.1e-21 77.6 0.0 1.3e-21 77.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 KIY67323.1 - 7.5e-05 22.8 0.0 0.00011 22.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain BTB PF00651.31 KIY67324.1 - 0.00063 20.0 0.0 0.0013 19.0 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain DHO_dh PF01180.21 KIY67325.1 - 5.5e-95 318.0 0.0 6.9e-95 317.6 0.0 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.18 KIY67325.1 - 0.021 13.9 0.3 1.1 8.2 0.7 2.6 2 1 0 2 2 2 0 FMN-dependent dehydrogenase Dus PF01207.17 KIY67325.1 - 0.071 12.2 0.0 9.9 5.1 0.0 2.5 1 1 0 2 2 2 0 Dihydrouridine synthase (Dus) NMO PF03060.15 KIY67325.1 - 0.11 11.9 0.1 0.22 10.9 0.1 1.4 1 0 0 1 1 1 0 Nitronate monooxygenase EspB_PE PF18625.1 KIY67325.1 - 0.16 12.5 5.0 1.1 9.7 1.3 3.0 1 1 2 3 3 3 0 ESX-1 secreted protein B PE domain CENP-B_dimeris PF09026.10 KIY67326.1 - 4.4 7.7 10.9 10 6.6 10.9 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PhoU PF01895.19 KIY67328.1 - 0.033 14.6 0.4 0.35 11.4 0.0 2.4 2 0 0 2 2 2 0 PhoU domain Spc7 PF08317.11 KIY67330.1 - 0.00072 18.5 9.1 0.0013 17.7 5.6 2.3 3 0 0 3 3 3 1 Spc7 kinetochore protein DUF4164 PF13747.6 KIY67330.1 - 0.0013 19.0 17.8 0.25 11.6 1.0 3.6 2 1 1 3 3 3 2 Domain of unknown function (DUF4164) Vps51 PF08700.11 KIY67330.1 - 0.0044 17.1 8.5 1.3 9.2 0.1 4.1 2 1 1 3 3 3 2 Vps51/Vps67 Baculo_PEP_C PF04513.12 KIY67330.1 - 0.026 14.6 9.3 0.51 10.4 2.2 3.6 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1359 PF07097.11 KIY67330.1 - 0.037 14.2 0.1 0.1 12.8 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1359) APG6_N PF17675.1 KIY67330.1 - 0.042 14.4 11.1 5.5 7.5 6.2 3.9 3 1 1 4 4 4 0 Apg6 coiled-coil region Tmemb_cc2 PF10267.9 KIY67330.1 - 0.049 12.8 6.7 0.0096 15.1 3.4 1.4 2 0 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein DUF1548 PF07579.11 KIY67330.1 - 0.067 13.5 0.1 0.16 12.3 0.1 1.6 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1548) ApoC-I PF04691.12 KIY67330.1 - 0.1 12.5 0.2 2.2 8.3 0.0 2.9 3 0 0 3 3 3 0 Apolipoprotein C-I (ApoC-1) DUF4559 PF15112.6 KIY67330.1 - 0.25 11.0 4.0 0.39 10.3 4.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) LPP PF04728.13 KIY67330.1 - 0.26 11.7 9.5 6.7 7.2 0.0 4.7 3 1 2 5 5 5 0 Lipoprotein leucine-zipper DUF3086 PF11285.8 KIY67330.1 - 0.27 10.3 3.3 0.82 8.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3086) DUF1664 PF07889.12 KIY67330.1 - 0.36 10.9 9.2 3.4 7.7 1.4 3.6 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) JIP_LZII PF16471.5 KIY67330.1 - 0.42 10.8 8.9 7.9 6.7 0.1 4.3 4 1 0 4 4 3 0 JNK-interacting protein leucine zipper II DUF848 PF05852.11 KIY67330.1 - 0.45 10.6 5.5 0.15 12.1 2.2 2.0 2 1 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) XhlA PF10779.9 KIY67330.1 - 0.63 10.3 3.7 46 4.3 0.3 3.8 2 1 1 3 3 3 0 Haemolysin XhlA DUF4618 PF15397.6 KIY67330.1 - 0.68 9.3 9.8 1.3 8.4 3.2 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4618) SOGA PF11365.8 KIY67330.1 - 0.68 11.1 9.8 8.7 7.6 0.2 3.6 4 0 0 4 4 4 0 Protein SOGA DUF4795 PF16043.5 KIY67330.1 - 0.74 9.4 8.4 4.2 6.9 6.3 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4795) TolA_bind_tri PF16331.5 KIY67330.1 - 0.74 9.9 12.0 1.2 9.3 0.1 4.6 3 2 1 4 4 4 0 TolA binding protein trimerisation NPV_P10 PF05531.12 KIY67330.1 - 0.81 10.2 8.5 1.2 9.6 0.4 4.3 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein Syntaxin_2 PF14523.6 KIY67330.1 - 0.91 9.9 7.5 49 4.4 3.5 3.3 2 1 1 3 3 3 0 Syntaxin-like protein Prominin PF05478.11 KIY67330.1 - 0.94 7.4 3.2 3.2 5.6 2.9 1.7 1 1 1 2 2 2 0 Prominin bZIP_1 PF00170.21 KIY67330.1 - 1.1 9.5 6.6 13 5.9 0.1 4.3 5 0 0 5 5 5 0 bZIP transcription factor Seryl_tRNA_N PF02403.22 KIY67330.1 - 1.3 9.3 6.5 1.3 9.3 1.7 2.9 3 1 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Tropomyosin_1 PF12718.7 KIY67330.1 - 2.3 8.4 9.8 2.7 8.1 2.2 2.9 3 1 0 3 3 3 0 Tropomyosin like Prefoldin_2 PF01920.20 KIY67330.1 - 2.6 8.0 8.4 37 4.3 0.1 4.1 4 1 0 4 4 4 0 Prefoldin subunit FlxA PF14282.6 KIY67330.1 - 3 7.9 6.1 45 4.1 0.5 3.4 3 0 0 3 3 3 0 FlxA-like protein HALZ PF02183.18 KIY67330.1 - 3.2 8.1 8.8 2.2 8.6 0.0 4.0 4 0 0 4 4 4 0 Homeobox associated leucine zipper TMF_TATA_bd PF12325.8 KIY67330.1 - 4.1 7.7 12.5 3.1 8.1 1.8 3.9 1 1 3 4 4 4 0 TATA element modulatory factor 1 TATA binding WXG100 PF06013.12 KIY67330.1 - 5.4 7.3 8.0 3.3 8.0 0.8 3.9 2 2 1 4 4 4 0 Proteins of 100 residues with WXG Fez1 PF06818.15 KIY67330.1 - 6.4 7.2 10.3 4.9 7.6 1.6 2.7 1 1 2 3 3 3 0 Fez1 DUF2373 PF10180.9 KIY67331.1 - 2.9e-18 65.4 0.4 5.3e-18 64.6 0.4 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) DUF3362 PF11842.8 KIY67331.1 - 0.7 10.2 8.3 3.4 8.0 0.4 3.1 2 1 0 3 3 3 0 Domain of unknown function (DUF3362) Cytochrom_B558a PF05038.13 KIY67331.1 - 8.8 5.9 6.6 14 5.2 6.0 1.6 1 1 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit Arf PF00025.21 KIY67332.1 - 3e-71 238.5 0.0 3.5e-71 238.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KIY67332.1 - 1.7e-13 50.8 0.0 2.2e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 KIY67332.1 - 2.6e-13 49.9 0.1 2e-08 33.8 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 KIY67332.1 - 5.9e-12 45.4 0.0 8e-12 44.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 KIY67332.1 - 1.9e-11 43.8 0.0 2.1e-11 43.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KIY67332.1 - 3e-09 36.6 0.0 3.7e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KIY67332.1 - 0.0002 21.4 0.0 0.00034 20.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase NOG1 PF06858.14 KIY67332.1 - 0.061 13.1 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) DUF1917 PF08939.10 KIY67333.1 - 2.7e-18 66.8 0.3 4.9e-18 66.0 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1917) EPL1 PF10513.9 KIY67334.1 - 2.9e-17 63.5 0.0 7.5e-17 62.2 0.0 1.7 1 0 0 1 1 1 1 Enhancer of polycomb-like TauD PF02668.16 KIY67335.1 - 4.8e-29 102.0 0.0 6.1e-29 101.6 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.16 KIY67336.1 - 3.2e-17 62.5 33.4 4.3e-17 62.1 33.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 KIY67336.1 - 2.7e-09 36.9 4.8 2.7e-09 36.9 4.8 2.2 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Sugar_tr PF00083.24 KIY67336.1 - 0.0003 19.8 16.9 0.002 17.1 16.8 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter ATPase_gene1 PF09527.10 KIY67336.1 - 0.065 13.4 0.4 0.065 13.4 0.4 3.3 3 0 0 3 3 3 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter AbrB PF05145.12 KIY67336.1 - 4.1 6.3 11.7 1.1 8.2 2.8 2.5 2 1 0 2 2 2 0 Transition state regulatory protein AbrB F-box-like PF12937.7 KIY67337.1 - 3e-08 33.4 1.1 8.3e-08 32.0 1.1 1.8 1 0 0 1 1 1 1 F-box-like CLASP_N PF12348.8 KIY67338.1 - 6.2e-70 235.3 0.0 2e-64 217.3 0.0 2.8 3 0 0 3 3 3 2 CLASP N terminal HEAT PF02985.22 KIY67338.1 - 8.2e-08 31.9 0.0 3.2 8.3 0.0 5.8 5 0 0 5 5 5 2 HEAT repeat Cnd1 PF12717.7 KIY67338.1 - 0.00018 21.6 0.0 0.27 11.3 0.0 3.5 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KIY67338.1 - 0.00035 21.0 0.0 0.47 11.0 0.0 3.5 2 0 0 2 2 2 2 HEAT-like repeat Cohesin_HEAT PF12765.7 KIY67338.1 - 0.058 13.7 0.0 3.8 7.9 0.0 3.1 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion MMS19_C PF12460.8 KIY67338.1 - 0.12 11.5 0.0 0.25 10.4 0.0 1.4 1 0 0 1 1 1 0 RNAPII transcription regulator C-terminal RINGv PF12906.7 KIY67340.1 - 0.002 18.2 8.8 0.0035 17.4 8.8 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_4 PF14570.6 KIY67340.1 - 2.1 8.2 7.1 5 7.0 6.8 1.8 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain CBFD_NFYB_HMF PF00808.23 KIY67342.1 - 1e-19 70.6 1.3 2.1e-19 69.6 1.3 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KIY67342.1 - 0.0029 18.0 0.2 0.0076 16.6 0.0 1.7 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 KH_10 PF17905.1 KIY67342.1 - 0.063 13.7 0.2 0.17 12.3 0.1 1.8 1 1 1 2 2 2 0 GLD-3 KH domain 5 LSM PF01423.22 KIY67343.1 - 1.9e-21 75.5 0.0 2.1e-21 75.4 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KIY67343.1 - 0.023 14.8 0.0 0.029 14.5 0.0 1.1 1 0 0 1 1 1 0 Ataxin 2 SM domain Rdx PF10262.9 KIY67344.1 - 5.2e-25 87.4 0.0 6.3e-25 87.2 0.0 1.1 1 0 0 1 1 1 1 Rdx family AAA PF00004.29 KIY67345.1 - 1.2e-33 116.3 0.0 2e-33 115.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KIY67345.1 - 1.6e-08 34.9 0.2 5.3e-07 30.0 0.2 2.9 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 KIY67345.1 - 6.8e-08 33.1 0.1 2.1e-07 31.5 0.0 1.9 2 0 0 2 2 1 1 AAA ATPase domain AAA_2 PF07724.14 KIY67345.1 - 4.8e-06 26.8 0.0 9.2e-06 25.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 KIY67345.1 - 2.2e-05 25.0 0.0 4.6e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KIY67345.1 - 2.4e-05 24.4 0.0 4.5e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KIY67345.1 - 7.4e-05 22.8 0.2 0.031 14.2 0.2 2.2 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_24 PF13479.6 KIY67345.1 - 7.5e-05 22.5 0.0 0.00018 21.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KIY67345.1 - 0.00012 22.3 0.3 0.00032 20.9 0.0 2.0 2 1 0 2 2 1 1 AAA domain DUF815 PF05673.13 KIY67345.1 - 0.00013 21.3 0.0 0.011 14.9 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 KIY67345.1 - 0.00049 19.9 0.0 0.0012 18.6 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 KIY67345.1 - 0.00051 20.0 0.2 0.0017 18.3 0.2 2.0 1 1 0 1 1 1 1 NACHT domain TsaE PF02367.17 KIY67345.1 - 0.00086 19.3 0.0 0.0026 17.7 0.0 1.8 2 0 0 2 2 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE TIP49 PF06068.13 KIY67345.1 - 0.0013 18.0 0.0 0.0019 17.5 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 KIY67345.1 - 0.0013 18.8 0.1 0.0031 17.5 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 KIY67345.1 - 0.0013 18.4 1.1 0.29 10.7 0.0 2.9 2 1 1 3 3 3 1 AAA domain AAA_28 PF13521.6 KIY67345.1 - 0.0014 18.9 0.0 0.0049 17.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain KAP_NTPase PF07693.14 KIY67345.1 - 0.0017 17.7 0.0 0.16 11.2 0.0 2.3 1 1 1 2 2 2 1 KAP family P-loop domain AAA_30 PF13604.6 KIY67345.1 - 0.0021 17.8 0.0 0.0049 16.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 KIY67345.1 - 0.0023 17.7 0.1 0.0046 16.7 0.1 1.7 1 1 0 1 1 1 1 Cytidylate kinase RNA_helicase PF00910.22 KIY67345.1 - 0.0034 17.8 0.0 0.0085 16.5 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_11 PF13086.6 KIY67345.1 - 0.0038 17.1 0.5 0.0038 17.1 0.5 2.0 2 1 0 2 2 1 1 AAA domain IstB_IS21 PF01695.17 KIY67345.1 - 0.004 16.9 0.0 0.012 15.3 0.0 1.8 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_17 PF13207.6 KIY67345.1 - 0.0082 16.6 0.0 0.034 14.6 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA_7 PF12775.7 KIY67345.1 - 0.011 15.3 0.0 0.026 14.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region Viral_helicase1 PF01443.18 KIY67345.1 - 0.016 15.0 0.0 0.031 14.0 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 KIY67345.1 - 0.019 15.3 0.7 0.21 11.9 0.4 2.6 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KIY67345.1 - 0.019 15.5 0.0 0.037 14.6 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Rad17 PF03215.15 KIY67345.1 - 0.028 14.3 0.1 0.1 12.5 0.0 2.0 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_3 PF07726.11 KIY67345.1 - 0.045 13.6 0.0 0.13 12.1 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 KIY67345.1 - 0.047 12.9 0.0 0.081 12.2 0.0 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Mg_chelatase PF01078.21 KIY67345.1 - 0.058 12.8 0.1 0.15 11.5 0.0 1.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI PduV-EutP PF10662.9 KIY67345.1 - 0.075 12.8 0.1 0.22 11.3 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation PhoH PF02562.16 KIY67345.1 - 0.085 12.3 0.0 0.47 9.9 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein CPT PF07931.12 KIY67345.1 - 0.093 12.6 0.0 0.25 11.1 0.0 1.8 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein DnaB_C PF03796.15 KIY67345.1 - 0.11 11.7 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_13 PF13166.6 KIY67345.1 - 0.12 11.0 0.0 0.19 10.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KIY67345.1 - 0.13 12.8 0.0 0.26 11.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 KIY67345.1 - 0.15 11.4 0.4 1.7 7.9 0.0 2.5 2 1 1 3 3 3 0 KaiC Glyco_transf_21 PF13506.6 KIY67346.1 - 6.9e-30 103.8 0.3 4.3e-22 78.4 0.0 2.2 1 1 1 2 2 2 2 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 KIY67346.1 - 1.9e-17 64.0 0.1 2.3e-17 63.7 0.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 KIY67346.1 - 6.2e-05 23.0 1.6 6.2e-05 23.0 1.6 1.8 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 KIY67346.1 - 0.0013 18.6 0.0 0.002 17.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Aminotran_3 PF00202.21 KIY67347.1 - 2.6e-98 329.3 0.0 3.7e-98 328.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KIY67348.1 - 4.6e-77 259.7 0.0 6.2e-77 259.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KIY67348.1 - 1.1e-05 24.9 0.0 2.2e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 KIY67348.1 - 1.9e-05 23.4 0.0 3.7e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KIY67348.1 - 0.00033 19.7 0.0 0.00066 18.7 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KIY67348.1 - 0.00054 19.4 0.0 0.00096 18.6 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pertussis_S1 PF02917.14 KIY67348.1 - 0.0037 17.1 0.0 0.017 14.9 0.0 2.0 2 0 0 2 2 2 1 Pertussis toxin, subunit 1 Preseq_ALAS PF09029.10 KIY67348.1 - 0.065 13.7 5.8 1.9 9.0 5.5 3.0 2 1 0 2 2 2 0 5-aminolevulinate synthase presequence Acyl-CoA_dh_1 PF00441.24 KIY67349.1 - 2.6e-28 99.1 0.4 3.7e-28 98.6 0.4 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KIY67349.1 - 1.1e-17 64.0 0.0 5.4e-17 61.8 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KIY67349.1 - 8.7e-12 45.7 0.1 2.4e-11 44.3 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KIY67349.1 - 5.7e-10 39.6 0.3 1e-09 38.8 0.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain RRM_1 PF00076.22 KIY67350.1 - 1.1e-16 60.4 0.1 2.5e-16 59.3 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L19 PF01245.20 KIY67350.1 - 1.3e-14 54.1 0.1 2.3e-14 53.3 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L19 DUF4201 PF13870.6 KIY67350.1 - 0.018 14.7 1.6 0.031 14.0 1.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) GPS2_interact PF15784.5 KIY67350.1 - 0.019 15.4 4.3 0.046 14.2 4.3 1.6 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain V_ATPase_I PF01496.19 KIY67350.1 - 0.17 9.8 1.1 0.23 9.3 1.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PEARLI-4 PF05278.12 KIY67350.1 - 0.92 9.0 7.1 0.36 10.4 4.1 1.7 2 0 0 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) DUF4637 PF15470.6 KIY67350.1 - 1.6 8.4 6.9 1.2 8.8 5.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4637) IMD PF08397.11 KIY67351.1 - 1.7e-07 30.8 0.9 2.6e-07 30.2 0.9 1.2 1 0 0 1 1 1 1 IRSp53/MIM homology domain BTB PF00651.31 KIY67353.1 - 0.0082 16.4 0.1 0.035 14.3 0.0 2.1 2 1 0 2 2 2 1 BTB/POZ domain Clathrin PF00637.20 KIY67353.1 - 0.11 12.4 0.0 0.3 11.0 0.0 1.7 1 1 1 2 2 2 0 Region in Clathrin and VPS Fungal_trans PF04082.18 KIY67354.1 - 1.4e-27 96.4 0.0 4.1e-27 94.9 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY67354.1 - 8.7e-09 35.4 11.3 1.6e-08 34.5 11.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SPX PF03105.19 KIY67354.1 - 9 6.1 17.7 64 3.3 16.9 2.1 2 0 0 2 2 2 0 SPX domain DUF4551 PF15087.6 KIY67354.1 - 9.1 5.0 9.1 18 4.0 9.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Aldo_ket_red PF00248.21 KIY67355.1 - 5.6e-63 212.9 0.1 6.8e-63 212.6 0.1 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family RAG2 PF03089.14 KIY67355.1 - 0.14 11.1 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Recombination activating protein 2 tRNA-synt_2 PF00152.20 KIY67356.1 - 7.7e-90 301.2 0.0 2.3e-89 299.6 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KIY67356.1 - 8.2e-11 41.7 0.0 1.6e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Herpes_UL4 PF03277.13 KIY67357.1 - 0.17 11.5 0.2 0.22 11.1 0.2 1.1 1 0 0 1 1 1 0 Herpesvirus UL4 family DUF443 PF04276.12 KIY67358.1 - 0.003 17.4 0.3 0.55 10.0 0.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF443) WAPL PF07814.13 KIY67358.1 - 0.053 12.3 0.2 0.07 11.9 0.2 1.1 1 0 0 1 1 1 0 Wings apart-like protein regulation of heterochromatin RNA_pol_Rpc34 PF05158.12 KIY67359.1 - 2.4e-72 244.1 3.0 1.2e-64 218.9 0.5 2.3 2 0 0 2 2 2 2 RNA polymerase Rpc34 subunit RPA_C PF08784.11 KIY67359.1 - 0.03 15.0 0.5 0.11 13.2 0.0 2.1 2 0 0 2 2 2 0 Replication protein A C terminal DUF3504 PF12012.8 KIY67359.1 - 0.2 11.5 0.0 0.2 11.5 0.0 3.4 2 1 0 2 2 2 0 Domain of unknown function (DUF3504) Ribosomal_S25 PF03297.15 KIY67359.1 - 0.22 11.8 0.2 0.22 11.8 0.2 4.4 2 1 2 4 4 4 0 S25 ribosomal protein BUD22 PF09073.10 KIY67359.1 - 1.8 7.8 43.5 3.4 6.9 43.5 1.3 1 0 0 1 1 1 0 BUD22 Macoilin PF09726.9 KIY67359.1 - 9.6 4.6 18.8 15 4.0 18.8 1.2 1 0 0 1 1 1 0 Macoilin family F-box-like PF12937.7 KIY67360.1 - 1.1e-06 28.4 0.5 3.7e-06 26.7 0.5 1.9 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KIY67360.1 - 0.00071 19.4 2.9 1.4 8.8 0.0 2.9 2 0 0 2 2 2 2 F-box domain PAP1 PF08601.10 KIY67360.1 - 0.87 9.3 2.2 1.3 8.7 2.2 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 F-box-like PF12937.7 KIY67361.1 - 2.7e-08 33.6 1.5 7.4e-08 32.2 1.5 1.8 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KIY67361.1 - 0.00039 20.2 6.2 0.24 11.4 0.1 2.9 3 0 0 3 3 3 2 F-box domain F-box-like PF12937.7 KIY67362.1 - 5e-08 32.7 0.4 1.4e-07 31.2 0.4 1.9 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KIY67362.1 - 0.00071 19.4 6.1 0.27 11.2 0.0 2.7 2 0 0 2 2 2 2 F-box domain LRR_4 PF12799.7 KIY67362.1 - 0.15 12.5 0.1 75 4.0 0.0 4.4 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) DUF4140 PF13600.6 KIY67362.1 - 0.22 12.0 1.4 2.3 8.7 0.4 2.4 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF410 PF04190.13 KIY67363.1 - 9.3e-73 245.2 0.0 1.1e-72 244.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF410) TPR_2 PF07719.17 KIY67363.1 - 0.069 13.3 1.2 0.88 9.8 0.1 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KIY67363.1 - 0.13 12.5 0.1 28 5.0 0.1 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 ACPS PF01648.20 KIY67364.1 - 3.1e-11 43.4 0.0 4.6e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily E3_binding PF02817.17 KIY67364.1 - 0.17 12.3 0.0 1.2 9.6 0.0 2.2 2 0 0 2 2 2 0 e3 binding domain PfkB PF00294.24 KIY67365.1 - 1.1e-14 54.4 0.0 1.5e-14 54.0 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 KIY67365.1 - 0.0024 17.3 0.0 0.0033 16.9 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Cullin PF00888.22 KIY67366.1 - 4.4e-18 65.3 0.0 6.6e-18 64.7 0.0 1.1 1 0 0 1 1 1 1 Cullin family ANAPC2 PF08672.11 KIY67366.1 - 1.2e-14 54.5 0.0 2.4e-14 53.5 0.0 1.6 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 cwf21 PF08312.12 KIY67367.1 - 2.6e-12 46.7 5.7 2.6e-12 46.7 5.7 2.6 2 0 0 2 2 2 1 cwf21 domain Abhydrolase_1 PF00561.20 KIY67368.1 - 1.5e-20 73.9 0.0 1.6e-19 70.6 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIY67368.1 - 2.1e-17 64.5 7.5 2.4e-17 64.3 4.9 2.2 2 1 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIY67368.1 - 5.4e-16 58.6 0.0 2.2e-12 46.8 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Esterase PF00756.20 KIY67368.1 - 2.7e-06 27.2 0.0 4.7e-06 26.4 0.0 1.5 1 1 0 1 1 1 1 Putative esterase LIDHydrolase PF10230.9 KIY67368.1 - 0.00048 19.8 0.0 0.0012 18.4 0.0 1.6 2 0 0 2 2 2 1 Lipid-droplet associated hydrolase Ndr PF03096.14 KIY67368.1 - 0.0024 16.6 0.0 0.0062 15.3 0.0 1.6 2 0 0 2 2 2 1 Ndr family Ser_hydrolase PF06821.13 KIY67368.1 - 0.0049 16.8 0.0 0.0093 15.8 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase BAAT_C PF08840.11 KIY67368.1 - 0.005 16.8 0.0 1.2 9.0 0.0 2.2 2 0 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.13 KIY67368.1 - 0.018 14.9 0.0 2.5 7.9 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 KIY67368.1 - 0.05 13.4 0.0 0.15 11.8 0.0 1.8 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase DUF2423 PF10338.9 KIY67369.1 - 1e-13 51.2 5.3 2.6e-13 50.0 5.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2423) Pan3_PK PF18101.1 KIY67369.1 - 0.24 11.3 0.1 0.31 11.0 0.1 1.1 1 0 0 1 1 1 0 Pan3 Pseudokinase domain Collectrin PF16959.5 KIY67370.1 - 0.083 12.7 2.7 1.5 8.6 0.4 2.4 2 0 0 2 2 2 0 Renal amino acid transporter RIX1 PF08167.12 KIY67371.1 - 1.1e-36 126.3 8.5 3.9e-35 121.3 5.0 2.6 2 1 0 2 2 2 2 rRNA processing/ribosome biogenesis PCNP PF15473.6 KIY67371.1 - 0.038 14.7 1.1 0.13 13.0 1.1 1.9 1 0 0 1 1 1 0 PEST, proteolytic signal-containing nuclear protein family zf-C2H2 PF00096.26 KIY67372.1 - 0.00077 19.8 0.8 0.00077 19.8 0.8 2.4 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KIY67372.1 - 0.0039 17.4 1.0 0.0082 16.4 1.0 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KIY67372.1 - 0.014 16.2 0.7 0.014 16.2 0.7 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger SARA PF11409.8 KIY67372.1 - 0.016 15.4 1.4 0.041 14.1 1.4 1.7 1 1 0 1 1 1 0 Smad anchor for receptor activation (SARA) zf-H2C2_2 PF13465.6 KIY67372.1 - 0.018 15.5 0.5 0.018 15.5 0.5 2.5 2 0 0 2 2 2 0 Zinc-finger double domain zf-HYPF PF07503.12 KIY67372.1 - 0.039 13.7 0.7 0.039 13.7 0.7 1.9 2 0 0 2 2 2 0 HypF finger DUF1390 PF07150.11 KIY67372.1 - 0.059 13.1 0.1 0.083 12.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1390) HPIP PF15226.6 KIY67372.1 - 0.1 13.0 0.4 0.12 12.8 0.4 1.3 1 0 0 1 1 1 0 HCF-1 beta-propeller-interacting protein family Zn_Tnp_IS1595 PF12760.7 KIY67372.1 - 0.1 12.6 4.2 0.12 12.4 2.9 1.8 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Zn_ribbon_SprT PF17283.2 KIY67372.1 - 4.6 7.2 10.4 6.1 6.8 2.8 2.3 1 1 1 2 2 2 0 SprT-like zinc ribbon domain F-box PF00646.33 KIY67373.1 - 0.00014 21.6 0.1 0.00044 20.0 0.1 1.9 1 0 0 1 1 1 1 F-box domain Pkinase PF00069.25 KIY67374.1 - 2.8e-71 240.0 0.0 4.1e-71 239.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY67374.1 - 1.7e-38 132.4 0.0 2.7e-38 131.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY67374.1 - 1.7e-06 27.6 0.0 2.9e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like KA1 PF02149.19 KIY67374.1 - 0.00011 21.9 0.0 0.00021 21.0 0.0 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 RIO1 PF01163.22 KIY67374.1 - 0.0071 16.0 0.1 0.013 15.1 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 KIY67374.1 - 0.0083 15.1 0.2 0.016 14.2 0.2 1.4 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KIY67374.1 - 0.03 14.3 0.0 0.076 12.9 0.0 1.8 1 0 0 1 1 1 0 Phosphotransferase enzyme family Phage_T7_Capsid PF05396.11 KIY67374.1 - 0.11 12.9 0.0 0.39 11.1 0.0 1.9 1 0 0 1 1 1 0 Phage T7 capsid assembly protein YrbL-PhoP_reg PF10707.9 KIY67374.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Pkinase_fungal PF17667.1 KIY67374.1 - 1.4 7.6 3.8 0.47 9.2 0.0 2.0 2 0 0 2 2 2 0 Fungal protein kinase HD PF01966.22 KIY67378.1 - 4.5e-07 30.1 0.0 6.6e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 HD domain F-box-like PF12937.7 KIY67380.1 - 7.4e-05 22.6 1.5 0.00021 21.1 1.5 1.8 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KIY67380.1 - 0.0095 16.3 1.0 1.8 9.1 0.5 3.3 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) Acetyltransf_3 PF13302.7 KIY67381.1 - 0.01 16.5 0.1 0.02 15.5 0.0 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain CCG PF02754.16 KIY67383.1 - 0.037 14.2 0.3 0.039 14.2 0.3 1.1 1 0 0 1 1 1 0 Cysteine-rich domain Acetyltransf_3 PF13302.7 KIY67384.1 - 3.8e-05 24.4 0.0 7.2e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PEP-utilisers_N PF05524.13 KIY67384.1 - 0.0084 16.3 0.1 0.014 15.5 0.1 1.3 1 0 0 1 1 1 1 PEP-utilising enzyme, N-terminal SMBP PF16785.5 KIY67384.1 - 0.14 12.4 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 Small metal-binding protein Zn_clus PF00172.18 KIY67385.1 - 3e-09 36.8 7.6 6.2e-09 35.8 7.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PSI_integrin PF17205.3 KIY67385.1 - 0.0051 16.5 0.6 0.012 15.4 0.6 1.6 1 0 0 1 1 1 1 Integrin plexin domain zf-HC3 PF16827.5 KIY67386.1 - 0.25 11.6 2.1 3.5 7.9 0.1 2.9 3 0 0 3 3 3 0 zinc-finger SUR7 PF06687.12 KIY67387.1 - 2.8e-11 43.4 11.2 6.8e-11 42.2 11.1 1.7 1 1 0 1 1 1 1 SUR7/PalI family DuoxA PF10204.9 KIY67387.1 - 0.0061 15.6 2.3 0.01 14.9 2.3 1.3 1 0 0 1 1 1 1 Dual oxidase maturation factor Trp_oprn_chp PF09534.10 KIY67387.1 - 0.037 13.8 0.7 0.058 13.2 0.7 1.3 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) TMEM52 PF14979.6 KIY67387.1 - 0.041 13.8 0.1 8.5 6.3 0.0 2.3 2 0 0 2 2 2 0 Transmembrane 52 GPR_Gpa2_C PF11970.8 KIY67387.1 - 0.11 12.6 0.3 4.9 7.3 0.0 2.4 1 1 1 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 C-term DUF4293 PF14126.6 KIY67387.1 - 2.8 8.2 8.3 0.91 9.8 2.3 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4293) CsbD PF05532.12 KIY67389.1 - 0.00035 20.4 5.1 0.00035 20.4 5.1 1.7 1 1 1 2 2 2 1 CsbD-like RNA_pol PF00940.19 KIY67395.1 - 1.4e-176 587.4 0.0 1.9e-176 587.0 0.0 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 KIY67395.1 - 4.5e-79 266.3 0.0 7.4e-79 265.6 0.0 1.4 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal zf-H2C2_2 PF13465.6 KIY67396.1 - 0.024 15.0 2.4 0.025 15.0 0.2 2.3 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 KIY67396.1 - 0.25 12.3 0.6 0.25 12.3 0.6 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KIY67396.1 - 3.2 8.4 8.0 15 6.2 0.2 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2 PF00096.26 KIY67397.1 - 2.5e-08 33.9 15.7 0.0087 16.5 0.8 5.0 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIY67397.1 - 8e-06 26.3 13.9 0.78 10.8 0.2 5.3 5 0 0 5 5 5 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KIY67397.1 - 0.00058 20.2 1.8 0.012 16.0 0.7 5.0 6 0 0 6 6 6 3 Zinc-finger double domain FOXP-CC PF16159.5 KIY67397.1 - 0.0022 18.6 0.5 0.14 12.8 0.1 2.5 2 0 0 2 2 2 1 FOXP coiled-coil domain OrsD PF12013.8 KIY67397.1 - 0.0031 17.9 4.7 0.35 11.3 0.3 4.0 4 0 0 4 4 4 1 Orsellinic acid/F9775 biosynthesis cluster protein D zf-H2C2_5 PF13909.6 KIY67397.1 - 0.0052 16.5 7.2 0.022 14.5 0.7 3.5 3 0 0 3 3 3 1 C2H2-type zinc-finger domain zf-C2H2_8 PF15909.5 KIY67397.1 - 0.08 13.3 1.4 6 7.2 0.1 3.1 3 0 0 3 3 3 0 C2H2-type zinc ribbon zf-Di19 PF05605.12 KIY67397.1 - 0.45 10.8 10.3 5.2 7.4 1.1 3.8 2 2 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_aberr PF17017.5 KIY67397.1 - 0.57 10.3 3.4 42 4.2 0.3 3.3 3 1 1 4 4 4 0 Aberrant zinc-finger zf-C2H2 PF00096.26 KIY67398.1 - 2e-07 31.1 13.5 0.021 15.2 0.8 4.9 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KIY67398.1 - 0.00014 22.1 14.0 0.029 14.8 0.7 4.7 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KIY67398.1 - 0.00033 21.2 13.9 1.9 9.5 0.2 5.4 5 0 0 5 5 5 3 C2H2-type zinc finger FOXP-CC PF16159.5 KIY67398.1 - 0.013 16.1 0.5 0.35 11.5 0.1 2.4 2 0 0 2 2 2 0 FOXP coiled-coil domain zf-H2C2_5 PF13909.6 KIY67398.1 - 0.026 14.3 6.2 0.041 13.6 0.3 3.2 3 0 0 3 3 3 0 C2H2-type zinc-finger domain OrsD PF12013.8 KIY67398.1 - 0.09 13.2 5.3 0.87 10.1 0.3 3.8 4 0 0 4 4 4 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-Di19 PF05605.12 KIY67398.1 - 1.7 9.0 8.2 14 6.0 1.1 3.7 2 2 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Bgal_small_N PF02929.17 KIY67399.1 - 0.058 13.0 0.0 0.077 12.6 0.0 1.1 1 0 0 1 1 1 0 Beta galactosidase small chain IATP PF04568.12 KIY67400.1 - 1e-07 32.3 2.5 1.6e-07 31.7 2.5 1.5 1 1 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP Sec2p PF06428.11 KIY67400.1 - 0.0081 16.1 3.6 0.01 15.8 3.6 1.2 1 0 0 1 1 1 1 GDP/GTP exchange factor Sec2p TMF_DNA_bd PF12329.8 KIY67400.1 - 0.012 15.6 4.9 0.015 15.3 4.9 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Spc7 PF08317.11 KIY67400.1 - 0.016 14.1 4.4 0.02 13.8 4.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein UPF0449 PF15136.6 KIY67400.1 - 0.035 14.6 0.5 0.042 14.3 0.5 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 SlyX PF04102.12 KIY67400.1 - 0.039 14.6 2.5 0.055 14.1 2.5 1.4 1 0 0 1 1 1 0 SlyX CC2-LZ PF16516.5 KIY67400.1 - 0.043 14.2 3.7 0.053 13.9 3.7 1.2 1 0 0 1 1 1 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF4140 PF13600.6 KIY67400.1 - 0.045 14.2 1.0 0.055 13.9 1.0 1.3 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) CRISPR_Cas2 PF09827.9 KIY67400.1 - 0.077 13.2 0.3 0.17 12.1 0.2 1.6 1 1 0 1 1 1 0 CRISPR associated protein Cas2 ATP_sub_h PF10775.9 KIY67401.1 - 9e-27 92.9 1.1 1.5e-26 92.2 1.1 1.3 1 0 0 1 1 1 1 ATP synthase complex subunit h His_Phos_1 PF00300.22 KIY67402.1 - 1.5e-31 109.6 0.0 1.8e-30 106.1 0.0 1.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Gti1_Pac2 PF09729.9 KIY67403.1 - 2.9e-28 99.2 0.2 5.2e-26 91.8 0.3 2.2 1 1 0 2 2 2 2 Gti1/Pac2 family LPD15 PF18828.1 KIY67403.1 - 0.021 14.7 0.1 6.4 6.7 0.1 2.3 2 0 0 2 2 2 0 Large polyvalent-protein-associated domain 15 AIM3 PF17096.5 KIY67403.1 - 0.11 13.4 1.0 0.15 13.0 0.1 1.8 2 0 0 2 2 2 0 Altered inheritance of mitochondria protein 3 Tubulin_3 PF14881.6 KIY67404.1 - 4.3e-32 111.2 0.0 7.7e-32 110.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.9 KIY67404.1 - 5.6e-25 87.9 0.0 1e-24 87.1 0.0 1.4 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin PF00091.25 KIY67404.1 - 0.0085 16.3 0.0 0.049 13.8 0.0 2.0 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain DUF481 PF04338.12 KIY67405.1 - 0.033 14.2 0.1 0.033 14.2 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF481 TMEM72 PF16054.5 KIY67405.1 - 0.2 11.3 0.0 0.36 10.5 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein family 72 FMN_dh PF01070.18 KIY67406.1 - 3.9e-104 348.4 0.0 5.1e-104 348.0 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 KIY67406.1 - 1.3e-05 24.3 0.2 0.0015 17.7 0.1 2.1 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KIY67406.1 - 0.00044 19.5 0.1 0.00067 18.9 0.1 1.1 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.14 KIY67406.1 - 0.0071 15.7 0.0 2.8 7.2 0.1 2.3 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG Amidohydro_3 PF07969.11 KIY67408.1 - 0.0012 18.4 0.3 7.9 5.8 0.0 3.2 1 1 2 3 3 3 3 Amidohydrolase family HRM PF02793.22 KIY67408.1 - 0.023 15.0 0.1 21 5.5 0.0 3.7 4 0 0 4 4 4 0 Hormone receptor domain Podoplanin PF05808.11 KIY67409.1 - 0.016 15.3 0.3 0.077 13.1 0.1 2.0 2 1 0 2 2 2 0 Podoplanin Peptidase_M24 PF00557.24 KIY67410.1 - 2.6e-56 190.6 0.0 3.7e-56 190.1 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KIY67410.1 - 3.6e-40 136.5 0.0 6.9e-40 135.6 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain DUF5497 PF17601.2 KIY67410.1 - 0.013 15.8 0.1 0.037 14.4 0.1 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5497) Thaumatin PF00314.17 KIY67411.1 - 1.1e-72 244.1 16.0 1.3e-72 243.9 16.0 1.0 1 0 0 1 1 1 1 Thaumatin family Glyco_hydro_64 PF16483.5 KIY67411.1 - 0.0043 16.4 0.9 0.011 15.1 0.0 1.9 2 0 0 2 2 2 1 Beta-1,3-glucanase WHH PF14414.6 KIY67412.1 - 0.059 13.2 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 A nuclease of the HNH/ENDO VII superfamily with conserved WHH 2OG-FeII_Oxy PF03171.20 KIY67413.1 - 8e-05 23.1 0.0 0.00071 20.0 0.0 2.2 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Peptidase_M20 PF01546.28 KIY67415.1 - 8e-32 110.6 0.0 1.4e-31 109.8 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KIY67415.1 - 1.1e-12 47.9 0.0 2.2e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KIY67415.1 - 0.0013 18.5 0.0 0.0037 17.0 0.0 1.8 1 1 0 1 1 1 1 Peptidase family M28 p450 PF00067.22 KIY67416.1 - 4.4e-77 259.8 0.0 1.4e-76 258.1 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 TrmO_C PF18389.1 KIY67416.1 - 0.016 15.3 0.1 0.052 13.7 0.0 1.8 2 0 0 2 2 2 0 TrmO C-terminal domain SET PF00856.28 KIY67417.1 - 1.2e-16 61.6 0.1 3.2e-16 60.2 0.0 1.8 1 1 0 1 1 1 1 SET domain Pre-SET PF05033.16 KIY67417.1 - 3.4e-08 34.1 6.2 3.4e-08 34.1 6.2 2.0 2 0 0 2 2 2 1 Pre-SET motif DUF4418 PF14387.6 KIY67418.1 - 0.036 14.3 0.1 0.072 13.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4418) Glyco_transf_28 PF03033.20 KIY67419.1 - 5.4e-31 107.5 0.0 9.5e-31 106.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.20 KIY67419.1 - 1.4e-23 82.9 0.4 1.3e-15 57.2 0.0 3.3 3 0 0 3 3 3 2 GRAM domain PH PF00169.29 KIY67419.1 - 6.1e-14 52.4 0.3 1.3e-12 48.1 0.3 2.6 2 0 0 2 2 2 1 PH domain PH_6 PF15406.6 KIY67419.1 - 2.6e-07 30.9 0.0 1.5e-06 28.5 0.0 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain UDPGT PF00201.18 KIY67419.1 - 9.7e-06 24.6 0.0 2.2e-05 23.5 0.0 1.5 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH_11 PF15413.6 KIY67419.1 - 9.2e-05 22.8 1.2 0.014 15.8 1.2 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 KIY67419.1 - 0.0026 17.8 0.1 0.0056 16.8 0.1 1.6 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 KIY67419.1 - 0.0075 16.5 0.1 0.016 15.5 0.1 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain SUR7 PF06687.12 KIY67420.1 - 2.2e-17 63.4 1.1 1.8e-16 60.4 1.1 1.9 1 1 1 2 2 2 1 SUR7/PalI family DUF2427 PF10348.9 KIY67420.1 - 0.028 14.2 1.1 0.028 14.2 1.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) Cadherin_C_2 PF16492.5 KIY67420.1 - 0.89 10.3 5.7 4 8.3 1.4 2.6 2 1 0 2 2 2 0 Cadherin cytoplasmic C-terminal Fig1 PF12351.8 KIY67420.1 - 1.2 9.0 10.7 2 8.3 6.2 2.2 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 Ac76 PF05814.11 KIY67420.1 - 8.9 6.4 9.2 0.69 10.0 0.1 2.5 3 0 0 3 3 3 0 Orf76 (Ac76) F-box-like PF12937.7 KIY67421.1 - 0.00012 21.9 0.1 0.00039 20.2 0.0 1.9 1 1 0 1 1 1 1 F-box-like DCB PF16213.5 KIY67422.1 - 1.1e-51 175.1 1.5 1.1e-51 175.1 1.5 2.3 2 0 0 2 2 2 1 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 KIY67422.1 - 2e-50 170.8 1.8 2e-50 170.8 1.8 3.7 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Mon2_C PF16206.5 KIY67422.1 - 3.6e-24 85.0 0.5 4e-13 48.4 0.6 4.0 3 2 0 3 3 3 2 C-terminal region of Mon2 protein DUF1981 PF09324.10 KIY67422.1 - 4.3e-05 23.3 1.0 0.0023 17.8 0.0 3.8 5 0 0 5 5 5 1 Domain of unknown function (DUF1981) RTP1_C1 PF10363.9 KIY67422.1 - 0.0083 16.3 0.0 0.079 13.1 0.0 2.7 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 Glyco_hydro_72 PF03198.14 KIY67423.1 - 4.1e-90 302.2 0.2 4.1e-90 302.2 0.2 1.7 2 0 0 2 2 2 1 Glucanosyltransferase X8 PF07983.13 KIY67423.1 - 4.2e-17 62.6 3.9 1.1e-16 61.3 3.9 1.7 1 0 0 1 1 1 1 X8 domain RRM_1 PF00076.22 KIY67424.1 - 1.2e-14 53.8 0.1 1.6e-14 53.4 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 KIY67424.1 - 9.8e-07 28.6 1.9 9.8e-07 28.6 1.9 1.9 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.6 KIY67424.1 - 0.00019 21.2 0.7 0.00019 21.2 0.7 2.4 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_5 PF14787.6 KIY67424.1 - 0.00073 19.2 2.1 0.0017 18.0 2.1 1.6 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.6 KIY67424.1 - 0.0026 17.7 0.0 0.0067 16.4 0.0 1.7 1 0 0 1 1 1 1 Zinc knuckle RRM_7 PF16367.5 KIY67424.1 - 0.042 14.0 0.0 0.16 12.1 0.0 1.8 1 1 1 2 2 2 0 RNA recognition motif RhoGAP PF00620.27 KIY67425.1 - 5.6e-38 130.1 0.1 1.2e-37 129.0 0.1 1.6 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.23 KIY67425.1 - 7.8e-09 35.7 0.0 3.2e-08 33.7 0.0 2.1 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain Ysc84 PF04366.12 KIY67427.1 - 1.8e-39 134.4 0.3 3e-39 133.7 0.3 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_1 PF00018.28 KIY67427.1 - 3.4e-17 61.8 0.1 8.6e-17 60.5 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KIY67427.1 - 1.6e-14 53.5 0.0 4.2e-14 52.1 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 KIY67427.1 - 3.2e-13 49.1 0.0 2.4e-12 46.3 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain Piwi PF02171.17 KIY67428.1 - 1.6e-85 287.0 0.0 2.2e-85 286.6 0.0 1.1 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 KIY67428.1 - 1.5e-19 71.0 0.0 3.6e-19 69.7 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 KIY67428.1 - 2.6e-19 68.6 0.3 9.8e-19 66.8 0.1 2.1 2 0 0 2 2 2 1 Argonaute linker 1 domain ArgoL2 PF16488.5 KIY67428.1 - 4.3e-12 46.2 0.0 1.5e-11 44.5 0.0 2.0 1 0 0 1 1 1 1 Argonaute linker 2 domain PAZ PF02170.22 KIY67428.1 - 2.3e-11 43.6 0.0 4.2e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 PAZ domain ArgoMid PF16487.5 KIY67428.1 - 0.0027 17.9 0.0 0.0066 16.7 0.0 1.7 1 0 0 1 1 1 1 Mid domain of argonaute NCE101 PF11654.8 KIY67429.1 - 0.14 11.9 0.1 0.28 10.9 0.1 1.4 1 0 0 1 1 1 0 Non-classical export protein 1 NUDIX PF00293.28 KIY67430.1 - 2.2e-05 24.5 0.0 3.9e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain F-box-like PF12937.7 KIY67431.1 - 0.00035 20.4 0.2 0.0011 18.9 0.2 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY67431.1 - 0.0067 16.3 0.0 0.022 14.6 0.0 1.9 1 0 0 1 1 1 1 F-box domain DLH PF01738.18 KIY67433.1 - 1.6e-12 47.4 0.0 2.2e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family HKR_ArcB_TM PF18415.1 KIY67434.1 - 4.8 8.1 9.7 0.51 11.2 0.8 3.0 3 1 0 3 3 3 0 Histidine kinase receptor ArcB trans-membrane domain VMA21 PF09446.10 KIY67435.1 - 5.5e-10 39.2 7.3 8.1e-10 38.7 7.3 1.3 1 0 0 1 1 1 1 VMA21-like domain Wzz PF02706.15 KIY67435.1 - 0.067 13.5 0.1 0.12 12.7 0.1 1.3 1 0 0 1 1 1 0 Chain length determinant protein Alg6_Alg8 PF03155.15 KIY67436.1 - 1.8e-168 561.5 31.4 2.1e-168 561.3 31.4 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family adh_short_C2 PF13561.6 KIY67437.1 - 2e-55 187.9 0.1 5.2e-54 183.3 0.1 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIY67437.1 - 2.3e-50 170.8 2.0 3.1e-49 167.1 2.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIY67437.1 - 6e-11 42.6 0.3 1.4e-10 41.4 0.1 1.6 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KIY67437.1 - 1.4e-06 27.9 0.1 3.7e-06 26.6 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KIY67437.1 - 0.0075 15.7 0.1 0.017 14.6 0.0 1.5 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KIY67437.1 - 0.088 12.4 1.7 0.11 12.0 0.3 1.8 2 0 0 2 2 2 0 NmrA-like family THF_DHG_CYH_C PF02882.19 KIY67437.1 - 0.093 12.0 0.1 0.3 10.4 0.1 1.8 1 1 1 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain RmlD_sub_bind PF04321.17 KIY67437.1 - 0.13 11.3 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Rxt3 PF08642.10 KIY67438.1 - 0.00061 20.6 0.8 0.0068 17.2 0.0 2.4 2 0 0 2 2 2 1 Histone deacetylation protein Rxt3 ubiquitin PF00240.23 KIY67440.1 - 4.9e-11 42.2 0.0 8.8e-11 41.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KIY67440.1 - 0.0013 18.6 0.0 0.0025 17.6 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Blt1 PF12754.7 KIY67440.1 - 0.0015 18.8 0.6 0.0027 18.0 0.6 1.4 1 0 0 1 1 1 1 Blt1 N-terminal domain Rad60-SLD_2 PF13881.6 KIY67440.1 - 0.0025 17.9 0.0 0.005 16.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Polysacc_deac_1 PF01522.21 KIY67441.1 - 2e-33 114.9 0.0 4.5e-33 113.8 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 KIY67441.1 - 0.0094 15.2 0.0 0.018 14.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 NAP PF00956.18 KIY67442.1 - 8.3e-25 87.5 4.6 1.2e-22 80.4 1.7 3.2 1 1 1 2 2 2 2 Nucleosome assembly protein (NAP) DUF4462 PF14692.6 KIY67442.1 - 0.16 11.5 0.0 1.1 8.8 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4462) Syja_N PF02383.18 KIY67443.1 - 2e-83 280.4 0.0 2.4e-83 280.1 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain OAM_alpha PF16552.5 KIY67443.1 - 0.053 13.4 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 D-ornithine 4,5-aminomutase alpha-subunit LRR_9 PF14580.6 KIY67444.1 - 2.2e-66 222.6 0.9 3.1e-65 218.9 0.1 2.0 2 0 0 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.7 KIY67444.1 - 1.4e-08 34.9 7.8 5.1e-05 23.5 2.6 3.4 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KIY67444.1 - 5.8e-07 29.2 4.5 1.9e-06 27.5 4.5 2.0 2 0 0 2 2 2 1 Leucine rich repeat SLX9 PF15341.6 KIY67444.1 - 0.034 14.5 1.1 0.058 13.8 1.1 1.3 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 DUF4149 PF13664.6 KIY67445.1 - 1.5e-20 73.4 2.8 1.5e-20 73.4 2.8 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) PDR_assoc PF08370.11 KIY67445.1 - 0.046 13.5 0.2 0.046 13.5 0.2 2.0 2 0 0 2 2 2 0 Plant PDR ABC transporter associated Vma12 PF11712.8 KIY67445.1 - 0.077 13.1 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Band_7_C PF16200.5 KIY67445.1 - 0.083 12.9 0.1 0.15 12.1 0.1 1.3 1 0 0 1 1 1 0 C-terminal region of band_7 Aldedh PF00171.22 KIY67446.1 - 2.7e-157 524.0 3.6 3.1e-157 523.8 3.6 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family UCR_TM PF02921.14 KIY67447.1 - 2.1e-12 47.4 2.3 8.8e-12 45.3 2.3 2.1 1 1 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.26 KIY67447.1 - 7.3e-12 45.1 0.0 1.3e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain MFS_1 PF07690.16 KIY67448.1 - 2.7e-31 108.8 30.1 8.9e-31 107.1 24.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily NPL4 PF05021.15 KIY67449.1 - 4.4e-99 331.7 0.0 5.8e-99 331.3 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 KIY67449.1 - 2.7e-65 219.0 0.0 4.8e-65 218.1 0.0 1.4 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region DUF5393 PF17371.2 KIY67449.1 - 0.06 11.5 0.2 0.098 10.8 0.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5393) UN_NPL4 PF11543.8 KIY67449.1 - 0.062 13.8 0.0 0.14 12.7 0.0 1.6 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 bZIP_2 PF07716.15 KIY67450.1 - 9.4e-10 38.4 10.5 1.2e-08 34.9 10.6 2.1 1 1 1 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.21 KIY67450.1 - 4.1e-05 23.6 6.4 9.1e-05 22.5 6.4 1.5 1 1 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 KIY67450.1 - 0.0029 18.1 0.4 0.0053 17.3 0.4 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor CCDC85 PF10226.9 KIY67450.1 - 0.15 11.7 4.9 0.039 13.6 0.6 1.8 1 1 1 2 2 2 0 CCDC85 family Thr_synth_N PF14821.6 KIY67453.1 - 1.3e-26 92.5 0.0 3.5e-26 91.2 0.0 1.8 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.25 KIY67453.1 - 1.9e-21 76.8 0.0 3.9e-21 75.7 0.0 1.5 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme zf-rbx1 PF12678.7 KIY67454.1 - 2.3e-24 85.4 12.8 3.1e-24 85.0 12.8 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KIY67454.1 - 1.1e-16 60.6 9.5 1.4e-16 60.3 9.5 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 KIY67454.1 - 5.9e-06 26.5 15.2 0.00025 21.3 15.2 2.3 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KIY67454.1 - 4.5e-05 23.2 3.7 4.5e-05 23.2 3.7 2.5 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIY67454.1 - 0.00092 19.0 11.5 0.017 15.0 11.5 2.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KIY67454.1 - 0.0057 16.4 2.5 0.0057 16.4 2.5 2.4 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 KIY67454.1 - 0.2 11.5 10.9 0.7 9.8 4.5 2.6 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KIY67454.1 - 0.24 11.4 7.2 0.88 9.6 7.2 2.0 1 1 0 1 1 1 0 RING-type zinc-finger FANCL_C PF11793.8 KIY67454.1 - 0.41 10.9 9.6 1.7 8.8 9.7 1.9 1 1 1 2 2 2 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 KIY67454.1 - 0.48 10.1 14.1 60 3.4 14.1 2.3 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type MFS_1 PF07690.16 KIY67456.1 - 6.7e-22 77.9 38.1 7.9e-17 61.2 17.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Med9 PF07544.13 KIY67457.1 - 0.00042 20.3 6.0 0.00079 19.5 6.0 1.4 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 DUF601 PF04642.12 KIY67457.1 - 0.0068 15.9 7.1 0.011 15.3 7.1 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF601 Med21 PF11221.8 KIY67457.1 - 2.4 8.4 14.7 0.12 12.6 7.4 2.2 2 0 0 2 2 2 0 Subunit 21 of Mediator complex zf-C3HC4_3 PF13920.6 KIY67458.1 - 5.7e-08 32.5 5.7 5.7e-08 32.5 5.7 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIY67458.1 - 4.8e-07 29.5 6.3 4.8e-07 29.5 6.3 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIY67458.1 - 1.2e-06 28.3 5.5 1.2e-06 28.3 5.5 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 KIY67458.1 - 2.4e-06 27.8 8.2 2.4e-06 27.8 8.2 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KIY67458.1 - 3.2e-06 26.9 9.4 3.2e-06 26.9 9.4 2.3 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KIY67458.1 - 3.7e-06 26.8 9.5 8.4e-06 25.7 9.5 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KIY67458.1 - 5.3e-05 23.3 4.8 5.3e-05 23.3 4.8 2.1 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 KIY67458.1 - 0.00027 20.7 0.7 0.00027 20.7 0.7 1.8 2 0 0 2 2 2 1 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 KIY67458.1 - 0.00033 20.5 4.2 0.00033 20.5 4.2 1.9 2 1 0 2 2 1 1 Prokaryotic RING finger family 4 Pellino PF04710.14 KIY67458.1 - 0.00076 18.3 0.2 0.0011 17.7 0.2 1.1 1 0 0 1 1 1 1 Pellino DUF1639 PF07797.14 KIY67458.1 - 0.02 14.9 0.4 0.044 13.8 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1639) FYVE PF01363.21 KIY67458.1 - 0.022 14.9 2.4 0.022 14.9 2.4 2.4 2 0 0 2 2 2 0 FYVE zinc finger NPV_P10 PF05531.12 KIY67458.1 - 0.027 14.9 0.0 0.057 13.9 0.0 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Zn_ribbon_17 PF17120.5 KIY67458.1 - 0.066 12.8 4.6 0.069 12.8 3.2 1.7 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type DUF1272 PF06906.11 KIY67458.1 - 0.96 9.6 5.9 13 5.9 0.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) zf-rbx1 PF12678.7 KIY67458.1 - 0.97 9.8 4.9 2.5 8.5 4.9 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain HypA PF01155.19 KIY67458.1 - 4.7 7.3 5.9 6 6.9 0.1 2.5 2 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 KIY67458.1 - 4.8 7.3 10.2 1.9 8.6 2.1 2.8 1 1 1 2 2 2 0 Double zinc ribbon TPT PF03151.16 KIY67459.1 - 2.1e-36 125.8 13.6 2.6e-36 125.5 13.6 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 KIY67459.1 - 6.5e-09 35.4 12.2 1.2e-08 34.5 12.2 1.5 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 KIY67459.1 - 0.003 17.7 32.7 0.11 12.6 12.0 2.5 2 0 0 2 2 2 2 EamA-like transporter family NAD_binding_5 PF07994.12 KIY67460.1 - 3e-144 480.3 0.0 3.5e-144 480.1 0.0 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 KIY67460.1 - 1.9e-45 153.6 0.0 3.4e-45 152.8 0.0 1.5 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Malic_M PF03949.15 KIY67461.1 - 3e-89 298.7 0.0 3.8e-89 298.4 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 KIY67461.1 - 4.9e-68 228.5 0.0 6.9e-68 228.0 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain TBCC PF07986.12 KIY67462.1 - 1.5e-26 92.5 4.1 2.5e-26 91.7 4.1 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C TBCC_N PF16752.5 KIY67462.1 - 4.7e-09 36.7 0.3 9.7e-09 35.7 0.3 1.4 1 0 0 1 1 1 1 Tubulin-specific chaperone C N-terminal domain DUF4482 PF14818.6 KIY67462.1 - 0.088 13.7 0.0 0.15 12.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4482) Bromo_TP PF07524.13 KIY67463.1 - 6.1e-11 42.2 0.3 9.4e-11 41.6 0.3 1.3 1 0 0 1 1 1 1 Bromodomain associated Histone PF00125.24 KIY67463.1 - 0.0039 17.6 0.1 0.0081 16.5 0.1 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 KIY67463.1 - 0.0051 17.0 0.0 0.012 15.8 0.0 1.6 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) DUF2514 PF10721.9 KIY67463.1 - 0.007 16.4 0.2 0.007 16.4 0.2 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2514) TFIID-31kDa PF02291.15 KIY67463.1 - 0.11 12.6 0.0 0.3 11.2 0.0 1.7 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit TFIID-18kDa PF02269.16 KIY67463.1 - 0.19 11.8 0.0 0.37 10.9 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit AAA_11 PF13086.6 KIY67465.1 - 6.4e-61 206.4 0.2 6.4e-61 206.4 0.2 2.1 2 0 0 2 2 1 1 AAA domain AAA_12 PF13087.6 KIY67465.1 - 1e-59 201.5 0.0 1.9e-59 200.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KIY67465.1 - 9.1e-09 35.4 0.1 0.0061 16.3 0.0 3.0 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 KIY67465.1 - 3.1e-07 30.3 0.0 5.5e-05 23.0 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KIY67465.1 - 3.5e-06 27.4 0.0 4.2e-05 23.9 0.0 2.7 2 1 0 2 2 2 1 AAA domain ResIII PF04851.15 KIY67465.1 - 3.3e-05 23.9 0.0 0.00069 19.6 0.0 2.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD_C_2 PF13538.6 KIY67465.1 - 6.2e-05 22.7 0.1 0.00034 20.4 0.0 2.2 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 KIY67465.1 - 0.00044 19.9 0.1 0.02 14.4 0.1 2.5 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain Vfa1 PF08432.10 KIY67465.1 - 0.0088 16.4 1.3 0.0088 16.4 1.3 1.9 2 0 0 2 2 2 1 AAA-ATPase Vps4-associated protein 1 UvrD_C PF13361.6 KIY67465.1 - 0.016 14.6 0.0 0.034 13.5 0.0 1.6 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain DUF2075 PF09848.9 KIY67465.1 - 0.088 12.0 0.6 4.5 6.4 0.0 2.9 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 KIY67465.1 - 0.13 12.6 0.1 5.5 7.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain RPN2_C PF18004.1 KIY67465.1 - 2 8.3 8.9 0.46 10.4 5.2 1.8 2 0 0 2 2 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Asp PF00026.23 KIY67468.1 - 0.00033 20.2 0.0 0.0049 16.3 0.0 2.0 2 0 0 2 2 2 2 Eukaryotic aspartyl protease ApbA PF02558.16 KIY67469.1 - 1e-18 67.4 0.0 1.8e-18 66.6 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 KIY67469.1 - 7.4e-18 65.0 0.0 3.1e-15 56.5 0.0 2.3 2 0 0 2 2 2 2 Ketopantoate reductase PanE/ApbA C terminal NAD_binding_7 PF13241.6 KIY67469.1 - 0.00077 19.9 0.0 0.0014 19.1 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Pyr_redox PF00070.27 KIY67469.1 - 0.0022 18.5 0.1 0.0066 17.0 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.21 KIY67469.1 - 0.014 14.8 0.1 0.023 14.0 0.1 1.3 1 0 0 1 1 1 0 ThiF family Sacchrp_dh_NADP PF03435.18 KIY67469.1 - 0.021 15.1 0.0 0.039 14.2 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 KIY67469.1 - 0.16 12.1 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase IlvN PF07991.12 KIY67469.1 - 0.18 11.4 0.1 0.33 10.5 0.1 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Epimerase PF01370.21 KIY67470.1 - 2e-18 66.7 0.0 2.9e-18 66.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KIY67470.1 - 4.3e-12 46.3 0.0 5e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KIY67470.1 - 3.1e-10 39.5 0.0 4.1e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KIY67470.1 - 2.6e-09 37.0 0.0 1.3e-07 31.4 0.0 2.3 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase DapB_N PF01113.20 KIY67470.1 - 0.0034 17.5 0.1 0.0053 16.9 0.1 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus RmlD_sub_bind PF04321.17 KIY67470.1 - 0.0048 16.0 0.0 0.013 14.7 0.0 1.7 1 1 0 1 1 1 1 RmlD substrate binding domain Sacchrp_dh_NADP PF03435.18 KIY67470.1 - 0.0052 17.0 0.1 0.021 15.1 0.0 1.9 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain ELFV_dehydrog PF00208.21 KIY67470.1 - 0.012 15.3 0.0 0.018 14.8 0.0 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase TrkA_N PF02254.18 KIY67470.1 - 0.057 13.7 0.0 0.086 13.1 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain NmrA PF05368.13 KIY67470.1 - 0.14 11.7 0.2 0.57 9.7 0.2 1.9 1 1 0 1 1 1 0 NmrA-like family DUF2107 PF09880.9 KIY67470.1 - 0.15 12.2 0.0 0.29 11.3 0.0 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2107) 2-Hacid_dh_C PF02826.19 KIY67470.1 - 0.16 11.3 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 KIY67470.1 - 0.42 9.7 0.9 5.4 6.1 0.9 2.2 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Ribosomal_S30 PF04758.14 KIY67472.1 - 8.9e-28 96.3 7.7 1.1e-27 96.0 7.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S30 DIOX_N PF14226.6 KIY67473.1 - 1.6e-29 103.0 0.0 2.7e-29 102.3 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KIY67473.1 - 5.4e-16 58.9 0.0 1.1e-15 57.9 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fungal_trans PF04082.18 KIY67474.1 - 3.3e-07 29.6 0.0 6.4e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY67474.1 - 9.1e-07 28.9 8.2 1.9e-06 27.9 8.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pet127 PF08634.10 KIY67476.1 - 4e-40 138.0 0.0 2e-39 135.7 0.0 1.8 1 1 0 1 1 1 1 Mitochondrial protein Pet127 bZIP_1 PF00170.21 KIY67477.1 - 1.7e-07 31.2 3.5 1.7e-07 31.2 3.5 1.5 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 KIY67477.1 - 3.7e-06 26.9 3.9 3.7e-06 26.9 3.9 1.9 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 KIY67477.1 - 0.0054 17.2 2.6 0.0095 16.4 2.6 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor Peripla_BP_7 PF18610.1 KIY67477.1 - 0.049 13.8 0.1 0.13 12.5 0.1 1.7 1 0 0 1 1 1 0 Periplasmic binding protein domain CTK3 PF12243.8 KIY67478.1 - 5.2e-37 126.6 0.0 7.4e-37 126.1 0.0 1.2 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.8 KIY67478.1 - 1e-23 83.3 3.7 1e-23 83.3 3.7 2.5 2 0 0 2 2 2 1 CTD kinase subunit gamma CTK3 C-terminus DUF1840 PF08895.11 KIY67478.1 - 0.35 11.2 4.4 0.73 10.2 4.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) Sec62 PF03839.16 KIY67478.1 - 0.43 10.1 2.8 0.56 9.7 2.8 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 U79_P34 PF03064.16 KIY67478.1 - 0.45 9.8 8.9 0.74 9.1 8.9 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 CDC45 PF02724.14 KIY67478.1 - 0.49 8.6 9.4 0.56 8.4 9.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Tmemb_9 PF05434.11 KIY67478.1 - 3 7.7 6.4 5.9 6.8 6.4 1.4 1 0 0 1 1 1 0 TMEM9 Peptidase_S49_N PF08496.10 KIY67478.1 - 3.2 7.8 5.6 5.2 7.1 5.6 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Cation_efflux PF01545.21 KIY67479.1 - 7.4e-07 29.1 1.1 2.7e-06 27.2 1.1 1.8 1 1 0 1 1 1 1 Cation efflux family GTP1_OBG PF01018.22 KIY67480.1 - 5.3e-42 143.0 3.8 6.5e-30 103.8 0.9 2.7 3 0 0 3 3 3 2 GTP1/OBG MMR_HSR1 PF01926.23 KIY67480.1 - 5.8e-19 68.3 0.0 1e-18 67.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.19 KIY67480.1 - 3.6e-05 23.4 0.0 0.1 12.1 0.0 2.2 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain FeoB_N PF02421.18 KIY67480.1 - 0.0014 18.2 0.0 0.0024 17.4 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B ABC_tran PF00005.27 KIY67480.1 - 0.03 14.9 0.0 0.073 13.6 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Arf PF00025.21 KIY67480.1 - 0.036 13.5 0.0 7.7 5.9 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family MeaB PF03308.16 KIY67480.1 - 0.098 11.6 0.1 1.2 8.1 0.1 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 KIY67480.1 - 0.2 11.7 0.0 0.41 10.7 0.0 1.6 1 1 0 1 1 1 0 Dynamin family Pterin_bind PF00809.22 KIY67481.1 - 3.2e-66 223.5 1.0 4.9e-66 222.9 1.0 1.3 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.20 KIY67481.1 - 7.2e-36 123.1 0.0 1.5e-35 122.1 0.0 1.5 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) FolB PF02152.18 KIY67481.1 - 1.7e-25 89.7 1.4 7.7e-14 52.2 0.3 2.7 3 0 0 3 3 3 2 Dihydroneopterin aldolase Lipase_GDSL_2 PF13472.6 KIY67481.1 - 0.021 15.3 0.4 0.065 13.6 0.4 1.9 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family MLD PF11647.8 KIY67481.1 - 0.051 13.9 0.0 0.14 12.5 0.0 1.7 1 0 0 1 1 1 0 Membrane Localization Domain Peptidase_S24 PF00717.23 KIY67482.1 - 1.6e-06 28.0 0.0 3.4e-06 26.9 0.0 1.6 1 1 1 2 2 2 1 Peptidase S24-like DUF4761 PF15958.5 KIY67482.1 - 0.14 12.3 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4761) Abhydrolase_6 PF12697.7 KIY67483.1 - 4.7e-18 66.6 1.4 6.6e-18 66.1 1.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KIY67483.1 - 4e-11 43.0 1.2 8.3e-11 42.0 0.8 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIY67483.1 - 6.8e-11 41.9 0.1 9.4e-11 41.4 0.1 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 KIY67483.1 - 0.056 13.3 0.1 0.12 12.2 0.1 1.5 1 0 0 1 1 1 0 Serine hydrolase Thioesterase PF00975.20 KIY67483.1 - 0.083 13.0 0.3 0.16 12.0 0.3 1.7 1 1 0 1 1 1 0 Thioesterase domain PGAP1 PF07819.13 KIY67483.1 - 0.088 12.5 1.9 2 8.0 0.4 2.5 2 1 1 3 3 3 0 PGAP1-like protein PDZ_3 PF17815.1 KIY67483.1 - 0.13 12.2 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 PDZ domain Protoglobin PF11563.8 KIY67485.1 - 1.2e-38 132.5 0.2 1.4e-38 132.3 0.2 1.0 1 0 0 1 1 1 1 Protoglobin Amidohydro_1 PF01979.20 KIY67487.1 - 6.7e-10 38.8 0.0 1e-07 31.6 0.0 2.6 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 KIY67487.1 - 8.2e-09 35.4 5.8 0.00012 21.7 0.2 3.1 3 1 0 3 3 3 2 Amidohydrolase family Sec10 PF07393.11 KIY67488.1 - 1.4e-131 440.2 0.0 1.8e-131 439.9 0.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box PF00646.33 KIY67488.1 - 4.2e-06 26.5 0.1 1.1e-05 25.1 0.1 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KIY67488.1 - 0.0005 19.9 0.1 0.0096 15.8 0.1 2.4 2 0 0 2 2 2 1 F-box-like HMGL-like PF00682.19 KIY67488.1 - 0.032 13.8 0.3 0.057 13.0 0.3 1.3 1 0 0 1 1 1 0 HMGL-like RDV-p3 PF09231.10 KIY67488.1 - 0.13 10.0 0.0 0.2 9.3 0.0 1.2 1 0 0 1 1 1 0 Rice dwarf virus p3 ATP11 PF06644.11 KIY67490.1 - 5.9e-72 242.7 0.0 6.9e-72 242.5 0.0 1.0 1 0 0 1 1 1 1 ATP11 protein Kinesin PF00225.23 KIY67491.1 - 2.2e-79 266.8 0.0 3.7e-79 266.1 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KIY67491.1 - 2.8e-15 56.5 0.1 5e-12 46.0 0.0 3.3 4 0 0 4 4 4 2 Microtubule binding Spc7 PF08317.11 KIY67492.1 - 1.7e-55 188.1 15.7 2.3e-55 187.7 15.7 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein FolB PF02152.18 KIY67492.1 - 0.003 18.1 0.8 0.008 16.7 0.8 1.7 1 0 0 1 1 1 1 Dihydroneopterin aldolase Rhabdo_M1 PF03342.13 KIY67492.1 - 0.0069 15.8 1.7 0.012 15.0 1.7 1.3 1 0 0 1 1 1 1 Rhabdovirus M1 matrix protein (M1 polymerase-associated protein) CENP-F_leu_zip PF10473.9 KIY67492.1 - 0.016 15.2 14.8 0.066 13.2 4.9 2.7 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_13 PF13166.6 KIY67492.1 - 0.032 12.9 7.7 0.045 12.4 7.7 1.2 1 0 0 1 1 1 0 AAA domain Bacillus_HBL PF05791.11 KIY67492.1 - 0.033 14.0 5.2 0.42 10.4 1.3 2.8 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Fib_alpha PF08702.10 KIY67492.1 - 0.047 13.9 0.9 0.047 13.9 0.9 2.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF4407 PF14362.6 KIY67492.1 - 0.082 12.2 8.9 0.17 11.2 8.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GAS PF13851.6 KIY67492.1 - 0.082 12.2 13.8 0.018 14.4 9.2 2.0 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding DUF1664 PF07889.12 KIY67492.1 - 0.16 12.0 2.7 0.15 12.1 0.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 KIY67492.1 - 0.28 11.2 3.0 0.5 10.4 1.9 1.9 2 1 0 2 2 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4164 PF13747.6 KIY67492.1 - 0.3 11.4 8.9 0.32 11.3 4.4 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4164) ERM PF00769.19 KIY67492.1 - 0.48 10.2 17.7 0.019 14.8 10.7 1.9 2 0 0 2 2 2 0 Ezrin/radixin/moesin family FapA PF03961.13 KIY67492.1 - 0.75 8.3 3.5 1 7.9 3.5 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DivIC PF04977.15 KIY67492.1 - 0.88 9.4 6.3 0.71 9.7 2.2 2.6 1 1 2 3 3 3 0 Septum formation initiator Prefoldin_2 PF01920.20 KIY67492.1 - 1.6 8.7 9.4 13 5.8 3.4 2.8 1 1 2 3 3 3 0 Prefoldin subunit SlyX PF04102.12 KIY67492.1 - 3.5 8.3 7.6 0.65 10.7 0.9 3.1 3 1 0 3 3 2 0 SlyX TMF_DNA_bd PF12329.8 KIY67492.1 - 4.1 7.5 12.3 7.3 6.7 2.3 2.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding TMPIT PF07851.13 KIY67492.1 - 8.3 5.6 8.0 6 6.0 5.2 1.8 1 1 1 2 2 2 0 TMPIT-like protein ArAE_2_N PF10337.9 KIY67494.1 - 0.22 10.5 1.7 0.21 10.6 1.7 1.1 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal DivIVA PF05103.13 KIY67494.1 - 1.4 9.0 11.1 1.8 8.7 11.1 1.2 1 0 0 1 1 1 0 DivIVA protein DUF883 PF05957.13 KIY67494.1 - 2.3 8.8 10.2 11 6.7 1.1 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) p450 PF00067.22 KIY67496.1 - 6.1e-55 186.8 0.0 7.9e-55 186.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DASH_Duo1 PF08651.10 KIY67496.1 - 0.18 11.6 0.0 4.1 7.3 0.0 2.7 2 1 0 2 2 2 0 DASH complex subunit Duo1 Acatn PF13000.7 KIY67497.1 - 5.7e-152 507.0 28.9 4.7e-71 239.9 15.8 3.5 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 TauE PF01925.19 KIY67497.1 - 0.0043 16.7 3.7 0.0043 16.7 3.7 2.3 2 1 0 2 2 2 1 Sulfite exporter TauE/SafE GYF PF02213.16 KIY67498.1 - 8.9e-17 60.5 0.2 1.8e-16 59.5 0.2 1.5 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 KIY67498.1 - 0.0079 16.0 0.2 0.022 14.6 0.2 1.8 1 0 0 1 1 1 1 GYF domain 2 PA28_beta PF02252.18 KIY67499.1 - 1.9e-55 186.5 0.7 2.5e-55 186.1 0.7 1.2 1 0 0 1 1 1 1 Proteasome activator pa28 beta subunit PA28_alpha PF02251.18 KIY67499.1 - 2.8e-07 30.5 0.0 8.7e-07 28.9 0.0 1.9 1 0 0 1 1 1 1 Proteasome activator pa28 alpha subunit HEPN_DZIP3 PF18738.1 KIY67499.1 - 0.048 13.4 0.7 0.23 11.2 0.1 2.3 3 0 0 3 3 3 0 DZIP3/ hRUL138-like HEPN CRISPR_Cas2 PF09827.9 KIY67499.1 - 0.16 12.1 0.5 0.43 10.8 0.1 1.9 2 0 0 2 2 2 0 CRISPR associated protein Cas2 L51_S25_CI-B8 PF05047.16 KIY67501.1 - 2.6e-09 36.8 0.0 4.1e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain RNA_pol_Rpb4 PF03874.16 KIY67503.1 - 2.4e-21 76.3 0.9 3.4e-21 75.8 0.9 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 Fungal_trans PF04082.18 KIY67505.1 - 4.4e-25 88.2 0.0 6.6e-25 87.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY67505.1 - 2.5e-05 24.3 10.2 5.8e-05 23.1 10.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Utp12 PF04003.12 KIY67506.1 - 7.3e-24 84.1 0.1 1.2e-23 83.4 0.1 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family WD40 PF00400.32 KIY67506.1 - 0.00011 22.9 0.1 1.3 10.1 0.0 4.0 4 0 0 4 4 4 2 WD domain, G-beta repeat UTP15_C PF09384.10 KIY67506.1 - 0.078 12.7 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 UTP15 C terminal Pkinase PF00069.25 KIY67507.1 - 5.4e-75 252.2 0.0 6.7e-75 251.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY67507.1 - 4.2e-35 121.3 0.0 7.1e-35 120.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KIY67507.1 - 0.00079 18.5 0.0 0.024 13.6 0.0 2.1 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KIY67507.1 - 0.0017 17.7 0.0 0.004 16.5 0.0 1.6 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KIY67507.1 - 0.029 14.0 0.0 0.52 9.9 0.0 2.2 2 0 0 2 2 2 0 RIO1 family APH PF01636.23 KIY67507.1 - 0.045 13.7 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family HATPase_c PF02518.26 KIY67508.1 - 1.1e-27 96.8 0.1 2.7e-27 95.5 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KIY67508.1 - 3.3e-19 69.1 0.0 4.8e-18 65.4 0.0 2.6 2 0 0 2 2 2 1 Response regulator receiver domain AAA_16 PF13191.6 KIY67508.1 - 5.3e-16 59.5 2.5 2.7e-14 53.9 0.2 3.5 3 0 0 3 3 3 1 AAA ATPase domain HisKA PF00512.25 KIY67508.1 - 4.3e-14 52.3 0.0 1.7e-13 50.4 0.0 2.2 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.6 KIY67508.1 - 7.4e-10 39.3 0.0 2.3e-09 37.7 0.0 1.9 1 0 0 1 1 1 1 GAF domain Pkinase PF00069.25 KIY67508.1 - 1.9e-07 30.7 0.0 7.9e-07 28.7 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain GAF PF01590.26 KIY67508.1 - 9.1e-07 29.6 0.1 4.7e-06 27.3 0.0 2.2 2 0 0 2 2 2 1 GAF domain Pkinase_Tyr PF07714.17 KIY67508.1 - 0.00013 21.4 0.0 0.00027 20.3 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase GAF_3 PF13492.6 KIY67508.1 - 0.00014 22.2 0.0 0.00041 20.7 0.0 1.8 1 0 0 1 1 1 1 GAF domain AAA_22 PF13401.6 KIY67508.1 - 0.00029 21.1 1.8 0.0061 16.8 0.1 3.3 2 1 0 2 2 2 1 AAA domain DUF3369 PF11849.8 KIY67508.1 - 0.0085 16.3 0.1 0.087 13.0 0.1 2.8 1 1 0 1 1 1 1 Domain of unknown function (DUF3369) NACHT PF05729.12 KIY67508.1 - 0.042 13.8 7.3 0.15 12.0 2.4 3.4 2 1 0 2 2 2 0 NACHT domain AAA_5 PF07728.14 KIY67508.1 - 0.17 11.9 0.3 24 4.9 0.0 3.0 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Dna2 PF08696.11 KIY67509.1 - 1.5e-56 191.5 0.1 3.2e-56 190.4 0.1 1.5 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_12 PF13087.6 KIY67509.1 - 3.3e-50 170.5 0.0 6.3e-50 169.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KIY67509.1 - 3.7e-12 46.6 0.0 7.2e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KIY67509.1 - 2.2e-09 37.3 0.0 1e-08 35.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KIY67509.1 - 4e-06 27.2 0.0 9.9e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain Cas_Cas4 PF01930.17 KIY67509.1 - 6e-05 23.2 0.3 0.00051 20.2 0.3 2.4 1 1 0 1 1 1 1 Domain of unknown function DUF83 Helicase_RecD PF05127.14 KIY67509.1 - 0.0043 16.9 0.0 0.0083 16.0 0.0 1.5 1 0 0 1 1 1 1 Helicase SRP54 PF00448.22 KIY67509.1 - 0.0051 16.5 0.2 0.0096 15.6 0.2 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_29 PF13555.6 KIY67509.1 - 0.014 15.1 0.1 0.036 13.8 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 KIY67509.1 - 0.037 14.4 0.0 0.096 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 KIY67509.1 - 0.043 14.0 0.0 0.32 11.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain MobB PF03205.14 KIY67509.1 - 0.05 13.5 0.1 0.13 12.1 0.1 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.6 KIY67509.1 - 0.066 13.8 0.1 0.18 12.3 0.1 1.7 1 0 0 1 1 1 0 AAA domain UvrD-helicase PF00580.21 KIY67509.1 - 0.08 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain AAA_25 PF13481.6 KIY67509.1 - 0.089 12.4 0.1 0.48 10.0 0.0 2.2 3 0 0 3 3 3 0 AAA domain AAA_5 PF07728.14 KIY67509.1 - 0.12 12.4 0.2 0.83 9.7 0.1 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA PF00004.29 KIY67509.1 - 0.14 12.6 0.0 0.51 10.8 0.1 2.0 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KIY67509.1 - 0.18 11.3 0.1 0.35 10.4 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region DEAD PF00270.29 KIY67510.1 - 6.7e-38 130.2 0.1 1.3e-37 129.2 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIY67510.1 - 5.3e-29 100.8 0.1 3.9e-26 91.6 0.0 2.6 2 1 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 KIY67510.1 - 1.6e-08 34.7 0.0 2.7e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit VIT PF08487.10 KIY67511.1 - 8.2e-27 93.6 0.0 1.6e-26 92.7 0.0 1.5 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 KIY67511.1 - 1.6e-25 89.9 0.0 2.5e-25 89.2 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KIY67511.1 - 4.9e-16 59.5 0.0 1.1e-15 58.3 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KIY67511.1 - 1.5e-11 44.9 0.0 3.1e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 KIY67511.1 - 1.9e-06 27.4 0.0 3.7e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein VIT_2 PF13757.6 KIY67511.1 - 7.4e-05 22.6 0.0 0.00021 21.1 0.0 1.8 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain DUF2201 PF09967.9 KIY67511.1 - 0.02 15.0 0.0 0.052 13.7 0.0 1.7 1 0 0 1 1 1 0 VWA-like domain (DUF2201) Mito_carr PF00153.27 KIY67512.1 - 1.7e-53 178.5 0.9 5e-19 68.0 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein DEAD PF00270.29 KIY67513.1 - 3.7e-37 127.8 0.1 6.5e-37 127.0 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIY67513.1 - 1.2e-25 90.0 0.0 1.1e-24 86.9 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIY67513.1 - 1.3e-06 28.5 0.0 2.6e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 KIY67513.1 - 0.044 13.1 0.1 0.044 13.1 0.1 2.4 3 0 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit Aft1_HRR PF11787.8 KIY67513.1 - 0.21 12.8 1.8 0.56 11.4 1.8 1.8 1 0 0 1 1 1 0 Aft1 HRR domain HMG_box PF00505.19 KIY67514.1 - 1.5e-05 25.3 2.0 4.8e-05 23.7 2.0 1.9 1 1 0 1 1 1 1 HMG (high mobility group) box MATalpha_HMGbox PF04769.12 KIY67514.1 - 0.01 15.1 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 HMG-box DUF1459 PF07312.11 KIY67514.1 - 0.063 13.5 0.4 0.28 11.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1459) PolyA_pol PF01743.20 KIY67515.1 - 1.9e-15 57.4 0.0 3.2e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 KIY67515.1 - 2.2e-06 27.3 0.0 5.5e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.6 KIY67515.1 - 0.029 14.3 0.0 0.05 13.6 0.0 1.4 1 0 0 1 1 1 0 tRNA nucleotidyltransferase domain 2 putative Arm PF00514.23 KIY67517.1 - 1.5e-70 231.3 31.2 4.8e-13 48.6 0.1 11.8 11 1 1 12 12 12 10 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KIY67517.1 - 8.6e-18 64.5 7.2 0.0022 18.5 0.3 8.2 7 1 1 8 8 8 4 HEAT-like repeat HEAT_2 PF13646.6 KIY67517.1 - 1.5e-16 60.5 6.2 0.0099 16.3 0.1 7.5 3 3 5 8 8 8 6 HEAT repeats HEAT PF02985.22 KIY67517.1 - 2.3e-13 49.2 16.8 0.18 12.1 0.0 10.1 10 0 0 10 10 10 4 HEAT repeat Adaptin_N PF01602.20 KIY67517.1 - 1.2e-11 43.9 7.0 1.2e-07 30.7 0.3 2.9 2 1 1 3 3 3 2 Adaptin N terminal region Arm_2 PF04826.13 KIY67517.1 - 1.1e-10 41.4 7.0 5.1e-07 29.4 1.2 2.5 1 1 0 2 2 2 2 Armadillo-like KAP PF05804.12 KIY67517.1 - 2.8e-08 32.4 1.2 4.1e-08 31.9 1.2 1.2 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.14 KIY67517.1 - 1.7e-07 30.8 7.4 0.0034 16.7 2.4 4.3 2 1 1 3 3 3 3 V-ATPase subunit H Cnd1 PF12717.7 KIY67517.1 - 3.4e-06 27.2 5.2 0.014 15.4 0.1 4.6 2 2 3 5 5 5 3 non-SMC mitotic condensation complex subunit 1 DUF3361 PF11841.8 KIY67517.1 - 0.00052 20.0 5.4 1.1 9.1 0.1 3.8 1 1 1 3 3 3 2 Domain of unknown function (DUF3361) HEAT_PBS PF03130.16 KIY67517.1 - 0.0054 17.3 8.5 1.1e+02 3.9 0.2 7.5 8 2 0 8 8 7 0 PBS lyase HEAT-like repeat V-ATPase_H_C PF11698.8 KIY67517.1 - 0.0083 16.2 2.5 32 4.7 0.1 4.7 1 1 5 6 6 6 0 V-ATPase subunit H YqfD PF06898.11 KIY67517.1 - 0.12 11.2 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD Atx10homo_assoc PF09759.9 KIY67517.1 - 0.5 10.4 3.7 2.3 8.3 0.1 3.5 2 1 3 5 5 5 0 Spinocerebellar ataxia type 10 protein domain Glyco_hydro_16 PF00722.21 KIY67518.1 - 1.1e-05 25.0 0.1 4.2e-05 23.1 0.0 1.9 2 1 0 2 2 2 1 Glycosyl hydrolases family 16 BAG PF02179.16 KIY67519.1 - 1.1e-05 25.7 0.0 2.3e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 BAG domain Pkinase PF00069.25 KIY67520.1 - 6.3e-56 189.7 0.0 7.8e-56 189.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY67520.1 - 1.2e-42 146.0 0.0 1.5e-42 145.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIY67520.1 - 1.4e-06 27.4 0.1 2.1e-06 26.8 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KIY67520.1 - 8.7e-06 25.2 0.0 1.2e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KIY67520.1 - 0.0012 18.2 0.1 0.0023 17.3 0.1 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIY67520.1 - 0.0027 17.6 0.1 0.11 12.4 0.2 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KIY67520.1 - 0.072 12.0 0.1 0.14 11.1 0.1 1.4 1 0 0 1 1 1 0 Haspin like kinase domain MRP-L27 PF09809.9 KIY67521.1 - 1.5e-09 37.7 0.3 2.2e-09 37.1 0.3 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 GST_C_3 PF14497.6 KIY67522.1 - 6.8e-27 93.6 0.4 1.3e-26 92.7 0.4 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KIY67522.1 - 0.0006 20.0 0.1 0.001 19.2 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KIY67522.1 - 0.025 14.9 0.5 0.87 10.0 0.0 2.6 3 0 0 3 3 3 0 Glutathione S-transferase, N-terminal domain BAF1_ABF1 PF04684.13 KIY67522.1 - 0.068 12.2 0.3 0.093 11.8 0.3 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor GST_C_2 PF13410.6 KIY67522.1 - 0.12 12.4 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF3591 PF12157.8 KIY67523.1 - 1.4e-186 620.5 0.8 2.3e-186 619.8 0.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.6 KIY67523.1 - 0.00012 21.9 2.1 0.00025 20.8 2.1 1.5 1 0 0 1 1 1 1 Zinc knuckle TFIIF_beta PF02270.15 KIY67523.1 - 0.00068 19.7 0.1 0.0015 18.6 0.1 1.6 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain zf-CCHC PF00098.23 KIY67523.1 - 0.81 9.9 3.3 1.4 9.1 3.3 1.4 1 0 0 1 1 1 0 Zinc knuckle ERCC4 PF02732.15 KIY67524.1 - 4.5e-16 59.4 0.0 1.2e-15 58.1 0.0 1.7 2 0 0 2 2 2 1 ERCC4 domain HHH_8 PF14716.6 KIY67524.1 - 0.0023 18.3 0.0 0.0062 16.9 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain DUF508 PF04370.12 KIY67524.1 - 0.17 11.6 4.0 0.42 10.3 4.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF508) F-box-like PF12937.7 KIY67525.1 - 1.8e-08 34.1 0.0 7.3e-08 32.2 0.0 2.1 1 1 0 1 1 1 1 F-box-like Oxidored_FMN PF00724.20 KIY67527.1 - 5.4e-67 226.5 0.0 6.5e-67 226.2 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 KIY67527.1 - 0.087 11.9 0.1 0.42 9.6 0.0 1.9 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) HEM4 PF02602.15 KIY67528.1 - 3.7e-31 108.3 0.0 4.6e-31 108.0 0.0 1.1 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Arm PF00514.23 KIY67529.1 - 4.8e-12 45.5 23.4 5.2e-06 26.3 0.0 8.2 9 0 0 9 9 8 2 Armadillo/beta-catenin-like repeat HEAT PF02985.22 KIY67529.1 - 3.6e-08 33.0 22.6 0.0067 16.6 0.1 9.4 10 0 0 10 10 9 3 HEAT repeat HEAT_2 PF13646.6 KIY67529.1 - 5.6e-08 33.1 20.7 0.34 11.3 0.1 9.1 4 4 4 9 9 9 3 HEAT repeats HEAT_EZ PF13513.6 KIY67529.1 - 5.9e-05 23.5 12.5 1.1 9.8 0.0 6.6 6 0 0 6 6 6 3 HEAT-like repeat Adaptin_N PF01602.20 KIY67529.1 - 0.00014 20.6 8.1 0.00019 20.1 0.5 3.5 1 1 0 2 2 2 1 Adaptin N terminal region Cnd1 PF12717.7 KIY67529.1 - 0.001 19.1 6.8 0.21 11.6 0.0 5.2 5 2 0 6 6 6 1 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 KIY67529.1 - 0.0018 17.9 0.0 0.012 15.2 0.0 2.4 2 0 0 2 2 2 1 CLASP N terminal V-ATPase_H_C PF11698.8 KIY67529.1 - 0.015 15.4 0.1 0.13 12.4 0.0 2.7 3 1 1 4 4 4 0 V-ATPase subunit H RasGEF_N_2 PF14663.6 KIY67529.1 - 0.024 15.0 2.7 10 6.6 0.0 4.2 3 1 0 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain RTP1_C1 PF10363.9 KIY67529.1 - 0.063 13.5 4.0 0.16 12.2 0.1 3.4 3 1 1 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 Cohesin_HEAT PF12765.7 KIY67529.1 - 0.46 10.8 3.1 2 8.8 0.0 3.5 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion Abhydrolase_1 PF00561.20 KIY67532.1 - 5.6e-21 75.3 0.1 3.7e-16 59.6 0.1 2.3 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIY67532.1 - 2.4e-18 67.5 0.9 2.4e-18 67.5 0.9 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIY67532.1 - 2.4e-14 53.2 0.0 4.8e-12 45.6 0.0 2.0 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 KIY67532.1 - 0.00026 21.1 0.0 0.0005 20.1 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Peptidase_S9 PF00326.21 KIY67532.1 - 0.00043 19.8 0.0 0.008 15.7 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Esterase_phd PF10503.9 KIY67532.1 - 0.0006 19.4 0.0 0.86 9.1 0.0 2.2 2 0 0 2 2 2 2 Esterase PHB depolymerase DLH PF01738.18 KIY67532.1 - 0.0027 17.3 0.2 1.1 8.8 0.2 3.0 2 1 0 2 2 2 1 Dienelactone hydrolase family BAAT_C PF08840.11 KIY67532.1 - 0.0078 16.2 0.1 0.24 11.3 0.1 2.1 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_5 PF12695.7 KIY67532.1 - 0.029 14.2 0.1 2.3 7.9 0.1 2.9 3 1 0 3 3 3 0 Alpha/beta hydrolase family DUF2048 PF09752.9 KIY67532.1 - 0.082 12.0 0.1 0.12 11.5 0.1 1.1 1 0 0 1 1 1 0 Abhydrolase domain containing 18 Beta-APP PF03494.13 KIY67532.1 - 0.14 12.0 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) Mob1_phocein PF03637.17 KIY67533.1 - 9.7e-25 87.5 0.1 1.7e-24 86.8 0.1 1.3 1 0 0 1 1 1 1 Mob1/phocein family RdRP PF05183.12 KIY67534.1 - 2.1e-95 320.6 0.0 2.9e-95 320.1 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Glyco_hydro_28 PF00295.17 KIY67535.1 - 2.4e-41 141.9 0.3 2.4e-41 141.9 0.3 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 28 Beta_helix PF13229.6 KIY67535.1 - 0.0091 15.9 11.8 0.017 15.0 4.7 2.8 1 1 1 2 2 2 2 Right handed beta helix region ApbA PF02558.16 KIY67536.1 - 4e-33 114.2 0.1 5.9e-33 113.7 0.1 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 KIY67536.1 - 8.5e-27 93.8 0.1 1.9e-26 92.7 0.1 1.7 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal ThiF PF00899.21 KIY67536.1 - 0.11 11.8 0.1 0.43 9.9 0.0 1.9 2 0 0 2 2 2 0 ThiF family Fungal_trans PF04082.18 KIY67537.1 - 1.4e-21 76.7 0.0 2.2e-21 76.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY67537.1 - 1.6e-07 31.4 12.4 2.8e-07 30.5 12.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GTP_EFTU PF00009.27 KIY67538.1 - 5.7e-53 179.3 0.0 8.1e-53 178.8 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 KIY67538.1 - 2.3e-16 59.6 0.0 6.9e-16 58.1 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus MMR_HSR1 PF01926.23 KIY67538.1 - 6.3e-05 23.0 0.0 0.00058 19.9 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 KIY67538.1 - 0.0036 17.7 2.1 0.016 15.6 1.5 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MobB PF03205.14 KIY67538.1 - 0.018 14.9 0.0 7.7 6.4 0.0 2.7 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B RsgA_GTPase PF03193.16 KIY67538.1 - 0.095 12.6 0.0 1.5 8.7 0.0 2.5 2 1 1 3 3 3 0 RsgA GTPase Bromodomain PF00439.25 KIY67539.1 - 2e-19 69.4 0.0 6.7e-19 67.7 0.0 1.9 2 0 0 2 2 2 1 Bromodomain Bromo_TP PF07524.13 KIY67539.1 - 7.2e-06 25.9 0.0 1.3e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated RNA_polI_A34 PF08208.11 KIY67539.1 - 0.15 12.1 12.6 0.28 11.2 12.6 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Cnd2 PF05786.14 KIY67539.1 - 5 5.7 9.8 9.7 4.7 9.8 1.3 1 0 0 1 1 1 0 Condensin complex subunit 2 FancD2 PF14631.6 KIY67539.1 - 7.4 3.8 5.0 11 3.3 5.0 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease OPT PF03169.15 KIY67540.1 - 1.2e-145 486.6 42.5 1.4e-145 486.4 42.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein MFS_1 PF07690.16 KIY67541.1 - 1.7e-25 89.7 29.4 1.7e-25 89.7 29.4 2.0 1 1 0 2 2 2 1 Major Facilitator Superfamily RXT2_N PF08595.11 KIY67542.1 - 1.8 8.6 8.6 8.7 6.4 1.7 2.4 2 0 0 2 2 2 0 RXT2-like, N-terminal Exo_endo_phos PF03372.23 KIY67543.1 - 1.5e-10 41.0 2.0 3.2e-10 39.9 2.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Flavodoxin_1 PF00258.25 KIY67544.1 - 1.1e-25 90.6 0.0 2.4e-25 89.4 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.20 KIY67544.1 - 4.4e-24 85.3 0.0 6.6e-24 84.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 KIY67544.1 - 2.5e-12 47.4 0.0 4.5e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain UPF0086 PF01868.16 KIY67545.1 - 2.1e-28 98.1 0.0 3.6e-28 97.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function UPF0086 DUF2070 PF09843.9 KIY67546.1 - 0.64 8.2 10.4 0.88 7.8 10.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Thioredoxin PF00085.20 KIY67547.1 - 2.3e-57 191.4 0.1 6.4e-28 96.8 0.2 2.3 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.12 KIY67547.1 - 1.9e-22 80.0 0.8 1.9e-22 80.0 0.8 1.9 2 0 0 2 2 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain OST3_OST6 PF04756.13 KIY67547.1 - 3.8e-18 65.9 0.0 4e-09 36.2 0.0 2.4 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 KIY67547.1 - 1.7e-17 63.8 0.1 4.3e-10 40.0 0.1 2.7 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KIY67547.1 - 5.5e-11 42.6 0.4 0.054 13.8 0.1 4.3 2 2 2 4 4 4 4 Thioredoxin-like AhpC-TSA PF00578.21 KIY67547.1 - 2.9e-10 40.1 0.1 0.00025 21.0 0.0 2.5 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_6 PF13848.6 KIY67547.1 - 3.2e-09 37.0 0.0 0.00023 21.1 0.2 2.9 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KIY67547.1 - 7.1e-08 32.5 0.1 0.0016 18.6 0.0 2.7 3 0 0 3 3 3 2 Thioredoxin-like Redoxin PF08534.10 KIY67547.1 - 1.5e-07 31.2 0.1 0.009 15.7 0.1 2.4 2 0 0 2 2 2 2 Redoxin ERp29_N PF07912.13 KIY67547.1 - 1.8e-07 31.3 0.2 0.02 15.0 0.1 2.4 2 0 0 2 2 2 2 ERp29, N-terminal domain HyaE PF07449.11 KIY67547.1 - 3.2e-05 23.8 0.0 0.25 11.3 0.0 2.5 2 0 0 2 2 2 2 Hydrogenase-1 expression protein HyaE TraF PF13728.6 KIY67547.1 - 3.6e-05 23.7 0.3 0.17 11.7 0.0 2.5 3 0 0 3 3 2 2 F plasmid transfer operon protein Thioredoxin_3 PF13192.6 KIY67547.1 - 0.00015 21.8 0.0 0.74 9.9 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin domain Glutaredoxin PF00462.24 KIY67547.1 - 0.0047 17.1 2.7 0.65 10.2 0.3 3.4 2 2 0 2 2 2 1 Glutaredoxin Thioredoxin_9 PF14595.6 KIY67547.1 - 0.0076 16.0 0.0 2 8.2 0.0 2.5 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_5 PF13743.6 KIY67547.1 - 0.073 12.7 1.1 6.3 6.4 0.0 3.2 4 0 0 4 4 4 0 Thioredoxin Thioredoxin_4 PF13462.6 KIY67547.1 - 0.29 11.3 4.1 2.3 8.3 0.2 3.1 3 1 1 4 4 4 0 Thioredoxin Fungal_trans PF04082.18 KIY67548.1 - 1.6e-13 50.3 0.0 2.8e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY67548.1 - 7.2e-07 29.2 11.0 7.2e-07 29.2 11.0 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KIY67549.1 - 2.1e-15 56.5 0.0 4.3e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY67549.1 - 5e-07 29.7 10.1 8.4e-07 29.0 10.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Exo_endo_phos PF03372.23 KIY67550.1 - 3.1e-10 40.0 0.0 4.6e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RLL PF10036.9 KIY67550.1 - 0.0034 17.3 0.7 0.0043 16.9 0.0 1.5 2 0 0 2 2 2 1 RNA transcription, translation and transport factor protein Exo_endo_phos_2 PF14529.6 KIY67550.1 - 0.018 14.8 0.0 0.13 12.2 0.0 2.2 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase Scm3 PF10384.9 KIY67550.1 - 0.025 14.3 0.2 0.064 13.0 0.2 1.6 1 0 0 1 1 1 0 Centromere protein Scm3 OTU PF02338.19 KIY67551.1 - 3.5e-05 24.3 0.0 6.2e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease DUF155 PF02582.14 KIY67552.1 - 1e-41 143.0 0.0 1.3e-41 142.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Exo70 PF03081.15 KIY67553.1 - 2.7e-38 132.0 0.0 1.2e-37 129.9 0.0 1.8 2 0 0 2 2 2 1 Exo70 exocyst complex subunit Herpes_ICP4_N PF03584.15 KIY67553.1 - 0.041 13.7 0.0 1.4 8.8 0.0 2.7 2 1 1 3 3 3 0 Herpesvirus ICP4-like protein N-terminal region 4HBT PF03061.22 KIY67555.1 - 2.6e-13 50.1 0.1 5.1e-13 49.2 0.0 1.5 2 0 0 2 2 2 1 Thioesterase superfamily 4HBT_2 PF13279.6 KIY67555.1 - 1.4e-06 28.8 0.0 1.7e-06 28.5 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 KIY67555.1 - 0.00076 18.8 0.6 0.0013 18.1 0.6 1.3 1 0 0 1 1 1 1 Acyl-ACP thioesterase ATG27 PF09451.10 KIY67556.1 - 2.5e-20 73.5 0.0 3.1e-20 73.1 0.0 1.1 1 0 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.18 KIY67556.1 - 6.5e-05 23.0 0.0 0.047 13.8 0.0 2.1 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat Macoilin PF09726.9 KIY67557.1 - 0.056 12.0 27.3 0.077 11.5 27.3 1.2 1 0 0 1 1 1 0 Macoilin family SelP_N PF04592.14 KIY67557.1 - 1.9 7.8 15.0 0.72 9.2 12.6 1.5 1 1 1 2 2 2 0 Selenoprotein P, N terminal region SOG2 PF10428.9 KIY67557.1 - 6.6 5.8 31.3 8.1 5.5 31.3 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein DUF812 PF05667.11 KIY67557.1 - 7.4 5.3 6.9 8.6 5.1 6.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) HSP20 PF00011.21 KIY67558.1 - 1.2e-16 60.7 0.1 4.4e-10 39.6 0.0 2.1 1 1 1 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KIY67558.1 - 5.3e-10 38.7 0.0 1e-09 37.8 0.0 1.5 1 1 0 1 1 1 1 HSP20-like domain found in ArsA GvpH PF05455.11 KIY67558.1 - 0.0069 16.5 0.4 0.014 15.5 0.0 1.7 1 1 1 2 2 2 1 GvpH CBFD_NFYB_HMF PF00808.23 KIY67559.1 - 0.00014 22.1 0.0 0.00024 21.3 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DIOX_N PF14226.6 KIY67560.1 - 2.5e-28 99.2 0.0 4.1e-28 98.5 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KIY67560.1 - 2.8e-18 66.3 0.0 4.8e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF3318 PF11780.8 KIY67560.1 - 0.19 11.7 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3318) tRNA_bind PF01588.20 KIY67561.1 - 1.1e-28 99.2 0.0 1.8e-28 98.5 0.0 1.4 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C PF00043.25 KIY67561.1 - 0.0029 17.8 1.0 0.0055 16.9 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KIY67561.1 - 0.094 12.9 0.0 0.24 11.6 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain IHABP4_N PF16174.5 KIY67561.1 - 3.7 8.1 10.9 7.4 7.1 10.9 1.5 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal Glyco_hydro_88 PF07470.13 KIY67562.1 - 1.5e-16 60.4 0.7 2.4e-16 59.8 0.3 1.4 2 0 0 2 2 2 1 Glycosyl Hydrolase Family 88 Pro_isomerase PF00160.21 KIY67563.1 - 1.7e-53 181.1 0.0 2e-53 180.9 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Tyr_Deacylase PF02580.16 KIY67564.1 - 4.5e-48 163.4 0.0 5.3e-48 163.2 0.0 1.1 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase adh_short_C2 PF13561.6 KIY67565.1 - 1.1e-52 178.9 0.0 1.4e-52 178.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIY67565.1 - 1e-35 123.0 0.2 1.3e-35 122.6 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIY67565.1 - 2.2e-11 44.0 0.1 3.8e-11 43.2 0.1 1.3 1 0 0 1 1 1 1 KR domain Glu_dehyd_C PF16912.5 KIY67565.1 - 0.013 15.0 0.0 0.031 13.8 0.0 1.5 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus YjeF_N PF03853.15 KIY67565.1 - 0.017 15.0 0.0 0.49 10.3 0.0 2.2 2 0 0 2 2 2 0 YjeF-related protein N-terminus Pyr_redox_2 PF07992.14 KIY67565.1 - 0.06 12.6 0.0 0.084 12.1 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HA2 PF04408.23 KIY67566.1 - 2.2e-26 92.3 0.1 2.2e-26 92.3 0.1 2.6 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KIY67566.1 - 4.3e-20 71.9 0.0 1.3e-19 70.3 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KIY67566.1 - 1.2e-10 41.7 0.1 2.6e-09 37.4 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 KIY67566.1 - 4.3e-08 33.1 0.0 9.4e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KIY67566.1 - 2.9e-06 27.6 0.0 9.3e-06 26.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 KIY67566.1 - 0.0049 16.2 0.3 0.015 14.5 0.0 1.9 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 KIY67566.1 - 0.011 15.4 0.5 0.029 14.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KIY67566.1 - 0.015 15.6 0.0 0.039 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 KIY67566.1 - 0.016 14.6 0.0 0.03 13.6 0.0 1.4 1 0 0 1 1 1 0 KaiC ResIII PF04851.15 KIY67566.1 - 0.028 14.4 2.1 0.13 12.3 0.0 2.7 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit AAA_23 PF13476.6 KIY67566.1 - 0.21 12.1 14.5 0.46 11.0 0.0 3.2 3 0 0 3 3 3 0 AAA domain MFS_1 PF07690.16 KIY67567.1 - 1.2e-40 139.5 58.1 3.2e-40 138.1 43.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3522 PF12036.8 KIY67567.1 - 0.047 14.0 3.2 1.5 9.1 0.1 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3522) DnaJ_C PF01556.18 KIY67568.1 - 5.9e-37 127.0 0.0 8.2e-37 126.6 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KIY67568.1 - 2.2e-22 78.9 2.7 3.2e-22 78.4 2.7 1.2 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KIY67568.1 - 7.9e-10 39.0 17.3 7.9e-10 39.0 17.3 2.1 1 1 1 2 2 2 2 DnaJ central domain Anti-TRAP PF15777.5 KIY67568.1 - 0.84 9.6 21.1 0.35 10.9 5.7 3.1 1 1 2 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 KIY67568.1 - 6.3 6.9 9.7 3 7.9 1.5 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA SET PF00856.28 KIY67569.1 - 3e-05 24.5 0.0 0.013 15.9 0.0 2.3 1 1 1 2 2 2 2 SET domain Pkinase PF00069.25 KIY67570.1 - 1.1e-62 211.8 0.1 1.3e-62 211.6 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY67570.1 - 7.1e-20 71.4 0.0 9.7e-20 70.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KIY67570.1 - 1.7e-07 31.4 0.0 0.00017 21.6 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KIY67570.1 - 0.0072 15.1 0.0 0.012 14.4 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Choline_kinase PF01633.20 KIY67570.1 - 0.11 12.1 0.0 0.26 10.8 0.0 1.7 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 KIY67570.1 - 0.11 11.8 0.2 0.19 11.0 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Glyco_hydro_18 PF00704.28 KIY67572.1 - 5.7e-20 72.3 0.8 1e-19 71.4 0.8 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_5_12 PF02839.14 KIY67572.1 - 0.00032 21.1 21.1 0.0014 19.1 6.0 3.6 3 0 0 3 3 3 2 Carbohydrate binding domain CBM_5_12_2 PF14600.6 KIY67572.1 - 0.0016 18.4 15.8 0.14 12.2 3.9 2.8 2 0 0 2 2 2 2 Cellulose-binding domain DNA_pol_A_exo1 PF01612.20 KIY67573.1 - 1.9e-14 53.8 0.0 2.4e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 3'-5' exonuclease SSP160 PF06933.11 KIY67573.1 - 2.4 6.2 10.3 3.4 5.8 10.3 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 SPX PF03105.19 KIY67574.1 - 1.5 8.6 8.6 1.7 8.5 8.6 1.1 1 0 0 1 1 1 0 SPX domain BATS PF06968.13 KIY67576.1 - 4.7e-23 81.1 0.1 2.3e-22 78.9 0.0 2.1 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 KIY67576.1 - 9.2e-17 61.9 0.1 1.5e-16 61.2 0.1 1.3 1 0 0 1 1 1 1 Radical SAM superfamily LTXXQ PF07813.12 KIY67576.1 - 0.1 13.3 1.0 0.34 11.6 0.1 2.3 2 0 0 2 2 2 0 LTXXQ motif family protein BTG PF07742.12 KIY67578.1 - 2.1e-15 56.6 0.0 3.2e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 BTG family RAP1 PF07218.11 KIY67578.1 - 0.33 9.2 3.1 0.42 8.8 3.1 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) AF-4 PF05110.13 KIY67578.1 - 0.9 7.6 6.5 1.1 7.2 6.5 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Ribosomal_S27e PF01667.17 KIY67579.1 - 1.6e-28 98.1 4.6 2e-28 97.9 4.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 DUF3795 PF12675.7 KIY67579.1 - 0.03 14.7 1.1 0.24 11.8 1.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3795) Mu-like_Com PF10122.9 KIY67579.1 - 0.17 11.4 2.3 4.8 6.7 0.3 2.3 1 1 1 2 2 2 0 Mu-like prophage protein Com zf-C2HC5 PF06221.13 KIY67579.1 - 0.52 10.3 5.8 0.24 11.4 3.7 1.7 2 1 0 2 2 2 0 Putative zinc finger motif, C2HC5-type OAD_gamma PF04277.13 KIY67581.1 - 0.001 19.6 0.0 0.0013 19.3 0.0 1.2 1 0 0 1 1 1 1 Oxaloacetate decarboxylase, gamma chain Histone PF00125.24 KIY67583.1 - 3e-49 166.7 3.3 3.4e-49 166.6 3.3 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KIY67583.1 - 2.6e-05 24.5 0.1 4.3e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KIY67583.1 - 5.6e-05 23.2 0.1 0.0001 22.4 0.1 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 KIY67583.1 - 0.00076 19.7 0.1 0.0015 18.8 0.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PAF PF15715.5 KIY67583.1 - 0.0009 19.8 2.0 0.0011 19.5 2.0 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain Bromo_TP PF07524.13 KIY67583.1 - 0.087 12.8 0.1 0.15 12.1 0.1 1.4 1 0 0 1 1 1 0 Bromodomain associated RXT2_N PF08595.11 KIY67584.1 - 0.0077 16.3 0.0 0.11 12.5 0.0 2.3 2 0 0 2 2 2 1 RXT2-like, N-terminal BLM10_mid PF16507.5 KIY67585.1 - 4.3e-192 639.4 0.0 7.1e-192 638.7 0.0 1.4 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 KIY67585.1 - 1.3e-31 108.3 0.1 1.2e-30 105.2 0.0 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) HEAT PF02985.22 KIY67585.1 - 6.7e-08 32.1 9.3 0.025 14.8 0.1 7.5 7 0 0 7 7 7 2 HEAT repeat HEAT_2 PF13646.6 KIY67585.1 - 8.9e-07 29.2 6.7 0.019 15.3 0.0 6.0 6 1 0 6 6 6 2 HEAT repeats Arm PF00514.23 KIY67585.1 - 0.089 12.9 2.9 0.16 12.0 0.0 3.2 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KIY67585.1 - 0.18 12.3 1.1 15 6.2 0.1 4.6 5 1 1 6 6 6 0 HEAT-like repeat Translin PF01997.16 KIY67587.1 - 5.3e-66 222.5 0.0 6.2e-66 222.3 0.0 1.0 1 0 0 1 1 1 1 Translin family MCM PF00493.23 KIY67588.1 - 1.3e-103 345.0 0.3 3.4e-103 343.6 0.0 1.8 3 0 0 3 3 3 1 MCM P-loop domain MCM_OB PF17207.3 KIY67588.1 - 1.2e-33 115.6 0.0 2.9e-33 114.4 0.0 1.6 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KIY67588.1 - 1.4e-30 105.6 0.6 3.5e-30 104.3 0.6 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KIY67588.1 - 6.2e-15 55.7 0.1 1.4e-14 54.5 0.1 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KIY67588.1 - 6.1e-07 29.0 0.0 0.00025 20.5 0.0 2.5 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KIY67588.1 - 3.6e-05 23.8 0.0 7.9e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KIY67588.1 - 0.00012 21.9 0.8 0.00064 19.6 0.1 2.6 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase_C PF13335.6 KIY67588.1 - 0.024 15.2 0.5 0.27 11.9 0.1 2.9 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI C-terminal AAA PF00004.29 KIY67588.1 - 0.082 13.3 0.1 0.31 11.5 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) zf-C2H2 PF00096.26 KIY67590.1 - 5.4e-09 36.0 8.5 7.2e-07 29.3 0.3 4.0 5 0 0 5 5 5 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIY67590.1 - 6.3e-06 26.6 6.8 0.00057 20.5 0.1 3.8 5 0 0 5 5 5 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KIY67590.1 - 0.00017 21.9 13.4 0.042 14.3 2.0 3.5 4 0 0 4 4 4 2 Zinc-finger double domain zf_ZIC PF18366.1 KIY67590.1 - 0.0097 16.0 0.8 1.6 8.9 0.2 2.4 2 0 0 2 2 2 2 Zic proteins zinc finger domain zf-C2H2_jaz PF12171.8 KIY67590.1 - 0.015 15.6 2.2 0.51 10.7 0.1 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KIY67590.1 - 0.064 13.3 0.0 0.064 13.3 0.0 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger TRAF6_Z2 PF18048.1 KIY67590.1 - 0.073 13.2 1.7 0.16 12.1 0.2 2.4 2 0 0 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 zf-C2H2_3rep PF18868.1 KIY67590.1 - 0.16 12.6 1.1 3.1 8.5 0.1 2.5 1 1 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats Med6 PF04934.14 KIY67591.1 - 2.6e-36 124.3 0.9 5e-36 123.4 0.9 1.4 1 0 0 1 1 1 1 MED6 mediator sub complex component MitMem_reg PF13012.6 KIY67592.1 - 1.1e-25 90.2 0.1 2e-25 89.4 0.1 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 KIY67592.1 - 2.2e-15 56.7 0.0 4.2e-15 55.8 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease TIM21 PF08294.11 KIY67593.1 - 6.8e-22 77.9 0.0 1.4e-17 64.0 0.0 2.5 2 0 0 2 2 2 2 TIM21 ATP-synt_F PF01990.17 KIY67594.1 - 2.2e-33 114.4 0.1 2.6e-33 114.2 0.1 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit PIN_8 PF18476.1 KIY67594.1 - 0.031 14.1 0.1 0.037 13.9 0.1 1.1 1 0 0 1 1 1 0 PIN like domain Rad21_Rec8_N PF04825.13 KIY67594.1 - 0.13 12.5 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 N terminus of Rad21 / Rec8 like protein DUF2759 PF10958.8 KIY67594.1 - 0.18 11.5 0.0 9.8 6.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2759) SGT1 PF07093.11 KIY67595.1 - 2e-94 317.1 22.3 3e-91 306.7 22.3 3.3 1 1 0 1 1 1 1 SGT1 protein F-box-like PF12937.7 KIY67597.1 - 1.1e-07 31.6 0.2 2.8e-07 30.3 0.0 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIY67597.1 - 0.0026 17.6 2.1 0.014 15.2 0.1 3.1 3 0 0 3 3 3 1 F-box domain LRR_9 PF14580.6 KIY67597.1 - 0.1 12.1 0.0 0.85 9.1 0.1 2.1 2 0 0 2 2 2 0 Leucine-rich repeat PET PF06297.14 KIY67598.1 - 0.089 13.1 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 PET Domain Leucyl-specific PF14795.6 KIY67598.1 - 0.099 12.7 0.1 0.58 10.3 0.0 2.2 2 1 0 2 2 2 0 Leucine-tRNA synthetase-specific domain Clat_adaptor_s PF01217.20 KIY67599.1 - 1.3e-43 148.3 0.2 2e-43 147.7 0.2 1.3 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Osmo_CC PF08946.10 KIY67599.1 - 0.099 12.9 0.1 0.19 12.0 0.1 1.4 1 0 0 1 1 1 0 Osmosensory transporter coiled coil Pkinase PF00069.25 KIY67600.1 - 1e-39 136.5 0.0 5e-19 68.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIY67600.1 - 6.1e-12 45.4 0.0 1.4e-06 27.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIY67600.1 - 0.057 12.2 0.6 0.16 10.7 0.4 1.6 1 1 1 2 2 2 0 Fungal protein kinase Pkinase PF00069.25 KIY67601.1 - 2.5e-47 161.5 0.0 3.5e-27 95.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIY67601.1 - 1.5e-34 119.5 0.0 1.3e-21 77.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIY67601.1 - 3.4e-06 26.1 0.0 5.5e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KIY67601.1 - 0.0096 15.3 0.0 0.077 12.3 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Choline_sulf_C PF12411.8 KIY67601.1 - 0.14 12.0 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 Choline sulfatase enzyme C terminal DUF1640 PF07798.11 KIY67603.1 - 8.6e-56 188.7 8.8 9.8e-56 188.5 8.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) DUF5082 PF16888.5 KIY67603.1 - 0.0026 18.1 1.8 1.3 9.3 0.6 2.8 2 1 0 2 2 2 2 Domain of unknown function (DUF5082) T2SSK PF03934.13 KIY67603.1 - 0.007 15.8 0.2 0.01 15.3 0.2 1.2 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein K DotU PF09850.9 KIY67603.1 - 0.012 15.3 3.4 0.1 12.3 0.1 2.8 2 1 1 3 3 3 0 Type VI secretion system protein DotU Phage_GP20 PF06810.11 KIY67603.1 - 0.035 13.9 4.4 0.047 13.5 4.4 1.1 1 0 0 1 1 1 0 Phage minor structural protein GP20 V-ATPase_G PF03179.15 KIY67603.1 - 0.26 11.8 5.9 0.12 12.9 1.0 2.5 2 1 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit Flagellin_N PF00669.20 KIY67603.1 - 0.37 10.9 6.0 0.12 12.5 2.2 2.0 2 1 0 3 3 3 0 Bacterial flagellin N-terminal helical region NAD_binding_10 PF13460.6 KIY67604.1 - 8.2e-29 100.8 0.0 9.4e-29 100.6 0.0 1.0 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KIY67604.1 - 1.2e-07 31.6 0.1 2.7e-07 30.4 0.0 1.7 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KIY67604.1 - 0.00051 19.6 0.0 0.0006 19.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KIY67604.1 - 0.12 12.7 0.2 0.34 11.2 0.0 1.8 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain C2 PF00168.30 KIY67605.1 - 7.2e-16 58.4 0.0 1e-07 32.1 0.0 2.2 2 0 0 2 2 2 2 C2 domain MTS PF05175.14 KIY67606.1 - 1.7e-08 34.2 0.0 6.1e-06 25.9 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase small domain Methyltransf_24 PF13578.6 KIY67606.1 - 0.006 17.6 0.0 0.013 16.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIY67606.1 - 0.1 13.4 0.0 0.21 12.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Mito_carr PF00153.27 KIY67607.1 - 1.1e-20 73.4 0.0 1.7e-07 31.1 0.0 4.6 3 2 0 3 3 3 3 Mitochondrial carrier protein C2 PF00168.30 KIY67608.1 - 1.8e-82 272.3 0.4 2.4e-19 69.6 0.1 5.4 5 0 0 5 5 5 5 C2 domain DUF2484 PF10658.9 KIY67608.1 - 0.042 14.2 0.6 0.076 13.3 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2484) MMM1 PF10296.9 KIY67608.1 - 0.056 12.5 0.0 0.18 10.8 0.0 1.8 2 0 0 2 2 2 0 Maintenance of mitochondrial morphology protein 1 WW PF00397.26 KIY67609.1 - 5.3e-08 32.8 3.4 5.3e-08 32.8 3.4 2.0 2 0 0 2 2 2 1 WW domain BPL_LplA_LipB PF03099.19 KIY67610.1 - 1.1e-07 31.8 0.0 1.7e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family GDPD PF03009.17 KIY67612.1 - 7.1e-34 117.7 0.0 8.7e-34 117.4 0.0 1.1 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 KIY67612.1 - 4.8e-05 23.7 0.4 4.8e-05 23.7 0.4 2.7 3 0 0 3 3 3 1 Glycerophosphoryl diester phosphodiesterase family CHCH PF06747.13 KIY67613.1 - 1.6e-05 24.9 4.7 2.4e-05 24.3 4.7 1.3 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 KIY67613.1 - 0.0033 17.4 4.0 0.0051 16.8 4.0 1.3 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, NDUF_B7 PF05676.13 KIY67613.1 - 0.016 15.0 1.3 0.02 14.6 1.3 1.2 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Pet191_N PF10203.9 KIY67613.1 - 0.046 14.0 3.8 0.16 12.3 3.6 1.8 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.10 KIY67613.1 - 0.094 12.8 4.0 0.26 11.3 3.5 1.8 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like F-box-like PF12937.7 KIY67615.1 - 1.3e-08 34.5 0.1 3.6e-08 33.2 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY67615.1 - 3.5e-08 33.1 0.1 1.1e-07 31.5 0.1 1.9 1 0 0 1 1 1 1 F-box domain ArfGap PF01412.18 KIY67615.1 - 0.91 9.6 4.8 0.35 11.0 0.5 2.4 2 1 1 3 3 3 0 Putative GTPase activating protein for Arf NUDIX PF00293.28 KIY67617.1 - 2.9e-09 37.1 0.0 5.4e-09 36.2 0.0 1.6 1 1 0 1 1 1 1 NUDIX domain Sugar_tr PF00083.24 KIY67618.1 - 2.8e-91 306.6 19.8 3.3e-91 306.4 19.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY67618.1 - 5.9e-25 87.9 33.9 5.3e-15 55.2 12.4 2.8 2 1 0 3 3 3 2 Major Facilitator Superfamily MFS_4 PF06779.14 KIY67618.1 - 0.023 14.0 17.9 0.053 12.8 7.4 2.4 2 0 0 2 2 2 0 Uncharacterised MFS-type transporter YbfB TPR_19 PF14559.6 KIY67618.1 - 0.16 12.5 0.1 0.28 11.7 0.1 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TRI12 PF06609.13 KIY67618.1 - 0.54 8.6 10.6 0.027 12.9 4.4 1.8 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) zf-H2C2_2 PF13465.6 KIY67619.1 - 0.0078 16.6 16.1 0.061 13.8 0.9 3.4 3 0 0 3 3 3 2 Zinc-finger double domain FOXP-CC PF16159.5 KIY67619.1 - 0.02 15.5 8.8 1.6 9.4 0.0 4.0 3 2 1 4 4 4 0 FOXP coiled-coil domain F-box PF00646.33 KIY67620.1 - 5e-07 29.4 3.2 8.7e-07 28.7 1.0 2.5 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KIY67620.1 - 2.4e-05 24.1 1.4 8.6e-05 22.4 0.3 2.3 2 0 0 2 2 2 1 F-box-like F-box_4 PF15966.5 KIY67620.1 - 0.016 15.0 1.3 0.079 12.8 0.1 2.2 2 0 0 2 2 2 0 F-box Cas9_REC PF16592.5 KIY67620.1 - 0.05 12.3 0.0 0.071 11.8 0.0 1.1 1 0 0 1 1 1 0 REC lobe of CRISPR-associated endonuclease Cas9 ESCRT-II PF05871.12 KIY67620.1 - 0.075 13.3 1.3 0.13 12.5 1.3 1.4 1 0 0 1 1 1 0 ESCRT-II complex subunit AMP-binding PF00501.28 KIY67621.1 - 7.5e-90 301.5 0.1 1e-89 301.1 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KIY67621.1 - 0.0093 16.9 0.0 0.037 15.0 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain F-box PF00646.33 KIY67622.1 - 2.9e-06 27.0 1.1 9.8e-06 25.3 1.1 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KIY67622.1 - 1.6e-05 24.7 0.2 7e-05 22.6 0.2 2.2 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KIY67622.1 - 0.045 13.6 1.4 0.068 13.0 0.1 2.0 2 0 0 2 2 2 0 F-box Speriolin_C PF15059.6 KIY67622.1 - 0.14 12.3 0.1 0.25 11.5 0.1 1.3 1 0 0 1 1 1 0 Speriolin C-terminus Ribosomal_S27e PF01667.17 KIY67622.1 - 7.2 6.4 11.5 0.27 11.0 0.6 3.5 4 0 0 4 4 4 0 Ribosomal protein S27 Na_H_Exchanger PF00999.21 KIY67623.1 - 3.2e-75 253.3 34.7 3.9e-75 253.0 34.7 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF2062 PF09835.9 KIY67623.1 - 0.033 14.0 6.7 1.7 8.5 1.0 3.6 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2062) DUF202 PF02656.15 KIY67624.1 - 0.0003 21.2 3.2 0.0011 19.4 1.6 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Connexin PF00029.19 KIY67624.1 - 0.19 11.5 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 Connexin PD40 PF07676.12 KIY67625.1 - 0.6 10.1 0.0 0.6 10.1 0.0 2.7 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Hamartin PF04388.12 KIY67625.1 - 9.8 4.7 27.9 5.9 5.4 17.4 2.1 1 1 1 2 2 2 0 Hamartin protein SnoaL_2 PF12680.7 KIY67626.1 - 0.019 15.6 0.0 0.029 15.0 0.0 1.3 1 1 0 1 1 1 0 SnoaL-like domain Tox-PL-2 PF15643.6 KIY67626.1 - 0.19 11.8 0.0 0.31 11.2 0.0 1.3 1 0 0 1 1 1 0 Papain fold toxin 2 FtsJ PF01728.19 KIY67627.1 - 9.9e-10 38.8 0.0 1.5e-09 38.3 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Vault_4 PF17796.1 KIY67627.1 - 0.052 13.6 0.2 0.17 12.0 0.1 1.9 2 0 0 2 2 2 0 Major Vault Protein repeat domain Polysacc_synt_4 PF04669.13 KIY67627.1 - 0.061 12.9 0.0 0.15 11.6 0.0 1.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis Glyco_hydro_67M PF07488.12 KIY67627.1 - 0.089 11.9 0.1 0.16 11.0 0.1 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 67 middle domain Suv3_C_1 PF18147.1 KIY67629.1 - 0.14 12.0 0.1 0.28 11.1 0.1 1.5 1 0 0 1 1 1 0 Suv3 C-terminal domain 1 ASF1_hist_chap PF04729.13 KIY67630.1 - 4.7e-63 211.7 0.0 5.7e-63 211.5 0.0 1.1 1 0 0 1 1 1 1 ASF1 like histone chaperone RasGEF PF00617.19 KIY67631.1 - 7.1e-28 98.0 0.0 1.5e-27 97.0 0.0 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KIY67631.1 - 5.7e-09 36.2 0.8 1.3e-08 35.0 0.8 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif CtIP_N PF10482.9 KIY67631.1 - 0.74 9.9 2.0 1.2 9.2 0.3 2.0 2 0 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain AAA_12 PF13087.6 KIY67632.1 - 3.6e-43 147.5 0.0 5.4e-43 146.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KIY67632.1 - 6.3e-27 95.0 0.0 1.9e-13 50.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KIY67632.1 - 4.3e-15 55.9 0.0 1.2e-14 54.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KIY67632.1 - 3.4e-12 46.9 0.0 1.9e-11 44.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KIY67632.1 - 3.1e-05 23.8 0.0 1.8 8.2 0.0 3.5 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 KIY67632.1 - 5e-05 23.0 0.0 0.098 12.2 0.0 2.2 2 0 0 2 2 2 2 UvrD/REP helicase N-terminal domain PhoH PF02562.16 KIY67632.1 - 8.5e-05 22.1 0.0 0.19 11.1 0.0 2.2 2 0 0 2 2 2 2 PhoH-like protein ResIII PF04851.15 KIY67632.1 - 0.00049 20.1 0.0 0.0014 18.7 0.0 1.8 2 0 0 2 2 1 1 Type III restriction enzyme, res subunit zf-met PF12874.7 KIY67632.1 - 0.0022 18.3 0.3 0.0022 18.3 0.3 4.5 3 2 0 3 3 3 1 Zinc-finger of C2H2 type AAA_16 PF13191.6 KIY67632.1 - 0.0068 16.8 0.0 0.016 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KIY67632.1 - 0.0078 16.5 0.0 0.023 15.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain zf_UBZ PF18439.1 KIY67632.1 - 0.0096 15.5 2.1 7.3 6.3 0.6 3.3 3 0 0 3 3 3 1 Ubiquitin-Binding Zinc Finger UvrD_C_2 PF13538.6 KIY67632.1 - 0.058 13.2 1.0 0.19 11.5 0.2 2.3 2 1 0 2 2 1 0 UvrD-like helicase C-terminal domain AAA PF00004.29 KIY67632.1 - 0.072 13.5 0.0 0.28 11.6 0.0 2.1 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) Bac_DnaA PF00308.18 KIY67632.1 - 0.08 12.8 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_7 PF12775.7 KIY67632.1 - 0.1 12.1 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Helicase_RecD PF05127.14 KIY67632.1 - 0.11 12.4 0.0 0.65 9.8 0.0 2.1 2 0 0 2 2 2 0 Helicase AAA_5 PF07728.14 KIY67632.1 - 0.17 11.9 0.0 0.42 10.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) zf-C2H2_jaz PF12171.8 KIY67632.1 - 0.25 11.7 8.8 6.3 7.2 0.2 3.8 3 1 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Ribosomal_L37ae PF01780.19 KIY67632.1 - 1.9 8.6 9.5 33 4.6 0.1 3.1 2 1 0 2 2 2 0 Ribosomal L37ae protein family zf-C3H1 PF10650.9 KIY67632.1 - 4.7 7.0 6.5 0.59 9.9 0.8 2.4 2 0 0 2 2 2 0 Putative zinc-finger domain HsbA PF12296.8 KIY67633.1 - 8.7e-28 97.2 5.8 8.7e-28 97.2 5.8 2.2 2 1 0 2 2 2 1 Hydrophobic surface binding protein A NPV_P10 PF05531.12 KIY67633.1 - 0.0021 18.5 1.2 0.068 13.6 0.1 2.5 2 0 0 2 2 2 1 Nucleopolyhedrovirus P10 protein Neurensin PF14927.6 KIY67633.1 - 0.091 12.5 0.1 0.16 11.7 0.1 1.3 1 0 0 1 1 1 0 Neurensin Baculo_PEP_C PF04513.12 KIY67633.1 - 1.4 9.0 7.7 1.3 9.1 1.9 2.8 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus SnoaL_2 PF12680.7 KIY67634.1 - 0.00018 22.1 0.3 0.00035 21.2 0.3 1.6 1 1 0 1 1 1 1 SnoaL-like domain SnoaL_3 PF13474.6 KIY67634.1 - 0.015 15.5 0.1 0.023 15.0 0.1 1.5 1 1 0 1 1 1 0 SnoaL-like domain DUF4440 PF14534.6 KIY67634.1 - 0.1 13.0 0.1 0.15 12.5 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4440) Dioxygenase_C PF00775.21 KIY67636.1 - 5.9e-08 32.4 0.1 1.1e-07 31.4 0.1 1.4 1 0 0 1 1 1 1 Dioxygenase DUF2717 PF10911.8 KIY67637.1 - 0.11 12.2 0.2 9.1 6.1 0.0 2.6 2 2 0 2 2 2 0 Protein of unknown function (DUF2717) Spherulin4 PF12138.8 KIY67637.1 - 0.14 11.8 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 Spherulation-specific family 4 DUF983 PF06170.12 KIY67637.1 - 0.28 11.6 2.8 4.5 7.7 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF983) AAA_12 PF13087.6 KIY67638.1 - 3.2e-43 147.7 0.0 5.9e-43 146.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KIY67638.1 - 2.4e-25 89.8 0.0 1.1e-11 45.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KIY67638.1 - 1.2e-11 44.7 0.0 4.7e-11 42.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KIY67638.1 - 1.4e-10 41.7 0.0 8e-10 39.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 KIY67638.1 - 5e-06 26.3 0.0 0.035 13.6 0.0 2.3 2 0 0 2 2 2 2 UvrD/REP helicase N-terminal domain PhoH PF02562.16 KIY67638.1 - 0.0001 21.9 0.0 0.092 12.2 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein zf-met PF12874.7 KIY67638.1 - 0.0002 21.6 0.4 0.0002 21.6 0.4 3.7 5 0 0 5 5 4 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KIY67638.1 - 0.016 15.4 0.7 0.016 15.4 0.7 3.1 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding AAA PF00004.29 KIY67638.1 - 0.022 15.2 0.2 0.15 12.5 0.0 2.5 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 KIY67638.1 - 0.023 14.7 0.0 0.048 13.6 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit UvrD_C_2 PF13538.6 KIY67638.1 - 0.034 14.0 0.8 0.15 11.9 0.8 2.1 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_5 PF07728.14 KIY67638.1 - 0.056 13.5 0.0 0.16 12.0 0.0 1.8 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 KIY67638.1 - 0.074 12.6 0.0 0.21 11.1 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 KIY67638.1 - 0.1 12.0 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 KIY67638.1 - 0.11 12.8 0.0 0.49 10.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain ASH PF15780.5 KIY67638.1 - 0.5 10.6 2.6 16 5.8 2.2 2.9 1 1 1 2 2 2 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin zf-RRPl_C4 PF17026.5 KIY67638.1 - 0.92 9.6 2.8 6.1 7.0 0.0 2.3 2 0 0 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type zf-UBP PF02148.19 KIY67638.1 - 2.1 8.7 12.9 48 4.4 11.9 2.7 1 1 1 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein zf_UBZ PF18439.1 KIY67638.1 - 2.9 7.6 4.6 8.3 6.1 1.6 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-C2H2 PF00096.26 KIY67639.1 - 7.9e-12 44.9 32.6 0.0025 18.2 0.2 7.4 7 0 0 7 7 7 5 Zinc finger, C2H2 type FOXP-CC PF16159.5 KIY67639.1 - 7.9e-11 42.4 32.2 0.016 15.8 0.1 7.1 2 2 5 7 7 7 5 FOXP coiled-coil domain zf-H2C2_2 PF13465.6 KIY67639.1 - 3.7e-08 33.5 1.9 7.8e-06 26.1 0.2 7.3 8 0 0 8 8 8 3 Zinc-finger double domain zf-H2C2_5 PF13909.6 KIY67639.1 - 3.7e-08 33.0 27.9 0.039 13.7 0.2 7.0 6 0 0 6 6 6 5 C2H2-type zinc-finger domain OrsD PF12013.8 KIY67639.1 - 1e-07 32.4 24.4 0.41 11.1 2.0 6.9 5 2 2 7 7 7 5 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_8 PF15909.5 KIY67639.1 - 0.00081 19.6 20.6 0.0023 18.2 0.5 3.9 2 2 2 4 4 4 2 C2H2-type zinc ribbon Glutaredoxin PF00462.24 KIY67639.1 - 0.07 13.4 3.0 36 4.7 0.0 3.9 4 0 0 4 4 4 0 Glutaredoxin DUF1936 PF09151.10 KIY67639.1 - 1.9 8.5 22.7 12 5.9 0.3 6.4 7 0 0 7 7 7 0 Domain of unknown function (DUF1936) F-box PF00646.33 KIY67640.1 - 5e-06 26.3 2.2 6.9e-06 25.8 0.0 2.4 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KIY67640.1 - 5.9e-05 22.9 0.0 5.9e-05 22.9 0.0 2.6 3 0 0 3 3 3 1 F-box-like Phage_int_SAM_1 PF02899.17 KIY67640.1 - 0.1 12.9 5.1 0.67 10.3 0.2 3.3 2 1 1 3 3 3 0 Phage integrase, N-terminal SAM-like domain CCDC106 PF15794.5 KIY67640.1 - 0.38 10.4 6.5 0.88 9.2 6.5 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 F-box-like PF12937.7 KIY67642.1 - 0.00046 20.0 0.0 0.001 18.9 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY67642.1 - 0.0015 18.4 0.1 0.003 17.4 0.1 1.5 1 0 0 1 1 1 1 F-box domain RicinB_lectin_2 PF14200.6 KIY67643.1 - 1.6e-13 51.2 12.3 1.6e-12 48.0 1.3 2.9 1 1 1 3 3 3 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 KIY67643.1 - 0.00069 19.9 3.3 0.018 15.3 0.1 2.2 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain FGF PF00167.18 KIY67643.1 - 0.061 13.4 0.0 0.08 13.1 0.0 1.3 1 1 0 1 1 1 0 Fibroblast growth factor Fascin PF06268.13 KIY67643.1 - 0.076 13.2 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 Fascin domain G-alpha PF00503.20 KIY67644.1 - 1.4e-112 376.4 0.0 1.6e-112 376.2 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KIY67644.1 - 5.5e-12 45.5 0.2 1.4e-08 34.4 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family Zeta_toxin PF06414.12 KIY67644.1 - 0.0018 17.6 0.0 0.0046 16.3 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin TniB PF05621.11 KIY67644.1 - 0.008 15.6 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 Bacterial TniB protein Roc PF08477.13 KIY67644.1 - 0.0089 16.2 0.0 2.3 8.5 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 KIY67644.1 - 0.2 11.0 0.4 10 5.4 0.1 2.3 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region zf-H2C2_2 PF13465.6 KIY67645.1 - 1.4e-11 44.2 32.4 8.6e-06 26.0 0.5 7.1 6 1 1 7 7 7 4 Zinc-finger double domain FOXP-CC PF16159.5 KIY67645.1 - 5.9e-10 39.6 32.8 0.17 12.5 0.6 6.4 1 1 5 6 6 6 5 FOXP coiled-coil domain zf-C2H2 PF00096.26 KIY67645.1 - 0.00012 22.3 28.9 1 9.9 0.0 7.3 7 0 0 7 7 7 3 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 KIY67645.1 - 0.027 14.2 1.6 0.027 14.2 1.6 7.2 7 0 0 7 7 7 0 C2H2-type zinc-finger domain DUF1936 PF09151.10 KIY67645.1 - 0.61 10.0 0.1 0.61 10.0 0.1 5.0 6 0 0 6 6 6 0 Domain of unknown function (DUF1936) Apt1 PF10351.9 KIY67645.1 - 2.4 6.9 4.9 3.2 6.5 4.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain F-box PF00646.33 KIY67647.1 - 1e-07 31.6 0.3 3.5e-07 29.9 0.3 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KIY67647.1 - 2.7e-06 27.2 0.1 1e-05 25.3 0.1 2.0 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KIY67647.1 - 0.032 14.1 0.3 0.12 12.2 0.1 2.0 2 0 0 2 2 2 0 F-box Bap31 PF05529.12 KIY67648.1 - 6.1e-46 155.6 5.2 6.1e-46 155.6 5.2 1.4 2 0 0 2 2 2 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 KIY67648.1 - 1.4e-12 47.4 3.4 2.5e-12 46.6 3.4 1.3 1 0 0 1 1 1 1 Bap31/Bap29 cytoplasmic coiled-coil domain Cluap1 PF10234.9 KIY67648.1 - 0.037 13.4 0.1 0.057 12.8 0.1 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 DUF883 PF05957.13 KIY67648.1 - 0.093 13.3 0.5 0.093 13.3 0.5 1.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF948 PF06103.11 KIY67648.1 - 0.2 11.9 1.0 0.85 9.9 0.0 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DivIC PF04977.15 KIY67648.1 - 0.71 9.7 3.3 2.5 7.9 1.9 2.1 2 0 0 2 2 2 0 Septum formation initiator DPM3 PF08285.11 KIY67648.1 - 2.5 8.4 4.8 9.2 6.5 0.2 2.6 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) UCH PF00443.29 KIY67649.1 - 3.6e-38 131.5 0.0 5e-38 131.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KIY67649.1 - 2e-11 44.1 0.7 6.4e-10 39.1 0.7 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 KIY67649.1 - 1.1e-06 28.2 0.0 2.2e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family EF1_GNE PF00736.19 KIY67651.1 - 4.1e-33 113.4 1.9 8.1e-33 112.5 1.9 1.5 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 KIY67651.1 - 1.7e-13 50.7 4.4 1.7e-13 50.7 4.4 2.6 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_2 PF13410.6 KIY67651.1 - 0.00088 19.3 0.2 0.012 15.6 0.0 2.5 2 1 1 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KIY67651.1 - 0.003 17.7 0.1 0.0081 16.3 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KIY67651.1 - 0.0044 17.2 0.3 0.013 15.7 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain VbhA PF18495.1 KIY67651.1 - 0.0094 15.8 0.3 7 6.6 0.2 3.0 2 0 0 2 2 2 2 Antitoxin VbhA adh_short PF00106.25 KIY67655.1 - 1.4e-11 44.2 0.0 1.6e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIY67655.1 - 0.00014 21.5 0.0 0.00017 21.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Shikimate_DH PF01488.20 KIY67655.1 - 0.001 19.1 0.1 0.0016 18.6 0.1 1.3 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase KR PF08659.10 KIY67655.1 - 0.0012 18.8 0.0 0.0016 18.4 0.0 1.1 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KIY67655.1 - 0.0019 18.1 0.0 0.0025 17.7 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KIY67655.1 - 0.012 16.1 0.0 0.018 15.6 0.0 1.3 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Pyr_redox_2 PF07992.14 KIY67655.1 - 0.045 13.0 0.1 0.053 12.7 0.1 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Polysacc_synt_2 PF02719.15 KIY67655.1 - 0.053 12.6 0.0 0.065 12.4 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Methyltransf_16 PF10294.9 KIY67655.1 - 0.092 12.5 0.0 0.1 12.3 0.0 1.1 1 0 0 1 1 1 0 Lysine methyltransferase LDcluster4 PF18306.1 KIY67655.1 - 0.11 12.1 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 SLOG cluster4 family GIDA PF01134.22 KIY67655.1 - 0.12 11.5 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox PF00070.27 KIY67655.1 - 0.12 12.9 0.1 0.18 12.4 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KIY67655.1 - 0.14 12.7 0.0 0.18 12.3 0.0 1.2 1 0 0 1 1 1 0 Putative NAD(P)-binding adh_short PF00106.25 KIY67656.1 - 2.7e-08 33.5 0.0 5e-08 32.6 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIY67656.1 - 1.1e-06 28.4 0.0 3.5e-06 26.8 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 5_nucleotid_C PF02872.18 KIY67658.1 - 6.4e-27 94.7 0.0 1.4e-26 93.6 0.0 1.6 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 KIY67658.1 - 5.6e-07 30.3 0.1 1.1e-06 29.3 0.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase F-box-like PF12937.7 KIY67660.1 - 4.9e-09 35.9 1.5 4.9e-09 35.9 1.5 2.0 2 0 0 2 2 2 1 F-box-like Glyco_hydro_38N PF01074.22 KIY67661.1 - 4.3e-81 272.5 0.1 6.4e-81 271.9 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 KIY67661.1 - 6.7e-50 170.1 0.0 1e-49 169.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 KIY67661.1 - 3.5e-27 94.4 0.0 1.8e-26 92.1 0.0 2.1 2 0 0 2 2 2 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 KIY67661.1 - 3.7e-08 33.4 0.1 7.5e-08 32.4 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Glyco_hydro_57 PF03065.15 KIY67661.1 - 0.14 11.4 0.0 0.3 10.2 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 COesterase PF00135.28 KIY67662.1 - 1.8e-81 274.5 0.0 1.3e-79 268.5 0.0 2.0 1 1 0 1 1 1 1 Carboxylesterase family p450 PF00067.22 KIY67663.1 - 7.6e-63 212.9 0.0 1.2e-62 212.1 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Ribonuclease_3 PF00636.26 KIY67664.1 - 6e-37 126.5 0.0 7.2e-19 68.4 0.0 2.7 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KIY67664.1 - 1.1e-23 83.7 0.0 3.2e-12 46.7 0.0 3.2 2 1 0 2 2 2 2 Ribonuclease-III-like Helicase_C PF00271.31 KIY67664.1 - 4.1e-16 59.3 0.1 9.5e-16 58.1 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIY67664.1 - 1.6e-15 57.5 0.0 3.1e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Dicer_dimer PF03368.14 KIY67664.1 - 5.4e-15 55.3 0.7 2.5e-14 53.2 0.1 2.3 2 0 0 2 2 2 1 Dicer dimerisation domain DEAD PF00270.29 KIY67664.1 - 7.3e-14 51.9 0.0 1.5e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 KIY67664.1 - 9.2e-06 25.5 0.0 1.6e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 SWI2/SNF2 ATPase F-box-like PF12937.7 KIY67665.1 - 0.00099 19.0 0.0 0.0023 17.8 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY67665.1 - 0.04 13.8 0.0 0.5 10.3 0.0 2.4 2 0 0 2 2 2 0 F-box domain DUF2420 PF10336.9 KIY67667.1 - 3.5e-06 27.0 0.0 6.4e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) SCP2_2 PF13530.6 KIY67668.1 - 0.11 12.9 0.0 0.23 11.8 0.0 1.5 1 0 0 1 1 1 0 Sterol carrier protein domain DUF1324 PF07038.11 KIY67669.1 - 0.06 13.6 0.1 0.11 12.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1324) HTH_9 PF08221.11 KIY67670.1 - 2.8e-17 62.6 2.2 1.6e-13 50.5 0.3 3.6 3 0 0 3 3 3 2 RNA polymerase III subunit RPC82 helix-turn-helix domain RNA_pol_Rpc82 PF05645.13 KIY67670.1 - 1.5e-15 57.7 3.5 4.6e-13 49.5 1.1 3.5 3 1 0 3 3 3 2 RNA polymerase III subunit RPC82 TFIIE_alpha PF02002.17 KIY67670.1 - 9.5e-10 38.3 3.7 1.1e-07 31.7 0.1 3.9 4 0 0 4 4 4 2 TFIIE alpha subunit COesterase PF00135.28 KIY67671.1 - 3.6e-87 293.4 0.0 1.8e-85 287.8 0.0 2.0 1 1 0 1 1 1 1 Carboxylesterase family ULD PF16534.5 KIY67672.1 - 0.11 12.6 0.0 0.29 11.2 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-like oligomerisation domain of SATB UPF0060 PF02694.15 KIY67672.1 - 6.5 7.0 13.6 1.5 9.1 2.4 3.5 3 1 1 4 4 4 0 Uncharacterised BCR, YnfA/UPF0060 family DUF1328 PF07043.13 KIY67672.1 - 7.6 6.8 10.9 6.5 7.1 0.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1328) Aldedh PF00171.22 KIY67673.1 - 3.9e-67 226.8 0.0 5e-67 226.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family F-box-like PF12937.7 KIY67675.1 - 2.6e-07 30.4 2.5 2.6e-07 30.4 2.5 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIY67675.1 - 0.38 10.7 7.9 0.28 11.1 3.6 2.9 2 1 0 2 2 2 0 F-box domain F-box-like PF12937.7 KIY67676.1 - 4e-07 29.8 0.4 4e-07 29.8 0.4 2.4 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 KIY67676.1 - 0.0066 16.3 1.2 0.038 13.9 0.4 2.8 2 1 0 2 2 2 1 F-box domain TRI5 PF06330.11 KIY67676.1 - 0.033 13.0 0.2 0.057 12.3 0.2 1.3 1 0 0 1 1 1 0 Trichodiene synthase (TRI5) F-box-like PF12937.7 KIY67677.1 - 2.6e-07 30.4 1.2 2.6e-07 30.4 1.2 2.6 3 1 0 3 3 3 1 F-box-like F-box PF00646.33 KIY67677.1 - 0.031 14.2 2.0 0.8 9.7 0.0 3.1 3 0 0 3 3 3 0 F-box domain PEPCK_ATP PF01293.20 KIY67678.1 - 1.6e-217 722.7 0.0 1.9e-217 722.5 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase ABC_tran PF00005.27 KIY67678.1 - 0.044 14.3 0.0 0.081 13.4 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 KIY67678.1 - 0.073 12.8 0.1 0.24 11.2 0.1 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.6 KIY67678.1 - 0.11 12.6 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 KIY67678.1 - 0.21 10.9 0.1 0.45 9.8 0.1 1.5 1 0 0 1 1 1 0 KaiC Epimerase PF01370.21 KIY67679.1 - 6.3e-12 45.5 0.0 2.2e-06 27.3 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KIY67679.1 - 2.7e-05 23.4 0.0 0.00017 20.8 0.0 2.1 2 1 0 2 2 2 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KIY67679.1 - 6e-05 22.3 0.0 0.00013 21.3 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 KIY67679.1 - 0.00031 20.2 0.0 0.0027 17.1 0.0 2.1 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KIY67679.1 - 0.00038 19.7 0.0 0.00064 18.9 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 KIY67679.1 - 0.00043 19.9 0.0 0.00065 19.3 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KIY67679.1 - 0.0048 16.8 0.0 0.0072 16.2 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KIY67679.1 - 0.043 12.8 0.0 0.16 10.9 0.0 1.8 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 KIY67679.1 - 0.053 13.9 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.10 KIY67679.1 - 0.087 12.7 0.0 0.2 11.5 0.0 1.6 1 1 0 1 1 1 0 KR domain Peptidase_M43 PF05572.13 KIY67680.1 - 3.2e-15 56.4 0.3 6.3e-15 55.4 0.0 1.6 2 0 0 2 2 2 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 KIY67680.1 - 0.0069 16.6 2.7 0.062 13.4 2.7 2.1 1 1 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M57 PF12388.8 KIY67680.1 - 0.013 15.1 0.4 1.1 8.8 0.0 2.1 2 0 0 2 2 2 0 Dual-action HEIGH metallo-peptidase Reprolysin_4 PF13583.6 KIY67680.1 - 0.048 13.3 1.1 0.092 12.4 0.1 1.8 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 KIY67680.1 - 0.052 14.1 0.0 0.2 12.2 0.0 1.9 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KIY67680.1 - 0.096 12.6 0.1 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DNA_ligase_ZBD PF03119.16 KIY67680.1 - 0.1 12.6 0.6 1.1 9.3 0.1 2.3 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain Nucleoporin_FG PF13634.6 KIY67681.1 - 1.2e-09 38.9 202.7 0.001 19.8 8.3 11.6 4 1 8 12 12 12 6 Nucleoporin FG repeat region LIN37 PF15306.6 KIY67681.1 - 0.13 12.4 2.2 0.56 10.4 2.2 2.1 1 0 0 1 1 1 0 LIN37 RNA12 PF10443.9 KIY67682.1 - 6.4e-115 384.4 2.1 7e-112 374.4 0.1 2.3 2 1 0 2 2 2 1 RNA12 protein AAA_16 PF13191.6 KIY67682.1 - 2.8e-05 24.6 0.5 0.00044 20.7 0.4 2.6 1 1 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 KIY67682.1 - 0.00041 20.3 0.0 0.003 17.5 0.0 2.2 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 KIY67682.1 - 0.0024 18.2 0.1 0.012 15.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KIY67682.1 - 0.0069 16.1 0.1 0.047 13.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KIY67682.1 - 0.0075 16.7 0.1 0.057 13.8 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 KIY67682.1 - 0.0085 16.0 0.0 0.12 12.3 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase T2SSE PF00437.20 KIY67682.1 - 0.0097 15.0 0.0 0.028 13.5 0.0 1.7 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_7 PF12775.7 KIY67682.1 - 0.02 14.4 0.0 0.08 12.5 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region cobW PF02492.19 KIY67682.1 - 0.024 14.2 0.0 0.05 13.2 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 KIY67682.1 - 0.036 14.2 0.0 0.12 12.5 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_24 PF13479.6 KIY67682.1 - 0.036 13.8 0.0 0.065 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain RraB PF06877.11 KIY67682.1 - 0.039 14.7 0.4 0.64 10.8 0.1 2.5 2 0 0 2 2 2 0 Regulator of ribonuclease activity B RRM_1 PF00076.22 KIY67682.1 - 0.078 12.8 0.0 0.32 10.9 0.0 2.0 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NB-ARC PF00931.22 KIY67682.1 - 0.1 11.8 0.1 0.39 9.9 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain ATP_bind_1 PF03029.17 KIY67682.1 - 0.1 12.3 0.1 1.1 9.0 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF4154 PF13689.6 KIY67682.1 - 0.12 12.6 0.1 0.28 11.4 0.1 1.5 1 0 0 1 1 1 0 YfiR/HmsC-like AAA_6 PF12774.7 KIY67682.1 - 0.15 11.0 0.0 0.3 10.0 0.0 1.4 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region AAA_23 PF13476.6 KIY67682.1 - 0.79 10.2 2.7 1.8 9.1 0.0 2.6 2 1 0 2 2 2 0 AAA domain SKN1 PF03935.15 KIY67683.1 - 0.0026 16.2 0.0 0.011 14.1 0.0 1.9 3 0 0 3 3 3 1 Beta-glucan synthesis-associated protein (SKN1) CrgA PF06781.12 KIY67683.1 - 0.0096 16.0 0.0 0.019 15.0 0.0 1.4 1 0 0 1 1 1 1 Cell division protein CrgA Tubulin PF00091.25 KIY67684.1 - 1.4e-69 234.2 0.0 2.7e-69 233.3 0.0 1.5 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KIY67684.1 - 4.4e-45 152.9 0.5 8e-45 152.1 0.1 1.6 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KIY67684.1 - 0.0013 19.0 0.0 0.0045 17.3 0.0 1.9 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 KIY67684.1 - 0.0035 17.0 0.0 0.0067 16.1 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Hrs_helical PF12210.8 KIY67684.1 - 0.015 15.8 0.3 0.037 14.6 0.3 1.6 1 0 0 1 1 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate F-box-like PF12937.7 KIY67686.1 - 4.2e-07 29.8 2.4 7.9e-06 25.7 1.0 2.8 2 0 0 2 2 2 2 F-box-like Pkinase PF00069.25 KIY67687.1 - 3.5e-19 69.2 0.0 5.2e-19 68.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY67687.1 - 1.4e-13 50.8 0.0 3.7e-13 49.4 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase MBF1 PF08523.10 KIY67688.1 - 1.3e-24 86.4 2.4 4.5e-24 84.7 3.0 1.6 2 0 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 KIY67688.1 - 1.6e-13 50.5 0.1 2.9e-13 49.6 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 KIY67688.1 - 3.2e-05 24.2 0.0 5.5e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 KIY67688.1 - 0.00097 19.1 0.0 0.0017 18.3 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain F-box-like PF12937.7 KIY67689.1 - 2.8e-06 27.1 1.8 6.8e-06 25.9 0.4 2.5 2 1 0 2 2 2 1 F-box-like Glyco_hydro_16 PF00722.21 KIY67690.1 - 1.8e-21 76.4 0.2 2.2e-21 76.1 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF1080 PF06439.11 KIY67690.1 - 0.0099 16.0 0.0 0.015 15.4 0.0 1.3 1 1 0 1 1 1 1 Domain of Unknown Function (DUF1080) WD40 PF00400.32 KIY67692.1 - 1.7e-39 133.1 18.6 1.2e-05 26.0 0.1 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.7 KIY67692.1 - 5.1e-12 45.5 0.2 1.1e-11 44.5 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY67692.1 - 7.8e-10 38.4 0.1 1.6e-09 37.4 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KIY67692.1 - 8.7e-05 22.4 0.1 0.00045 20.1 0.0 2.2 2 0 0 2 2 2 1 F-box Nup160 PF11715.8 KIY67692.1 - 0.0002 20.2 2.9 0.067 11.8 0.0 3.5 2 2 2 4 4 4 2 Nucleoporin Nup120/160 CSTF_C PF14304.6 KIY67692.1 - 0.089 12.4 0.3 0.22 11.1 0.3 1.6 1 0 0 1 1 1 0 Transcription termination and cleavage factor C-terminal NUDIX PF00293.28 KIY67693.1 - 2.1e-14 53.7 0.4 3.5e-11 43.3 0.1 2.4 1 1 1 2 2 2 2 NUDIX domain HhH-GPD PF00730.25 KIY67693.1 - 0.03 14.8 0.0 0.052 14.0 0.0 1.3 1 0 0 1 1 1 0 HhH-GPD superfamily base excision DNA repair protein ArAE_2_N PF10337.9 KIY67696.1 - 4.4e-49 167.8 0.5 4.4e-49 167.8 0.5 1.8 2 0 0 2 2 2 1 Putative ER transporter, 6TM, N-terminal ArAE_2 PF10334.9 KIY67696.1 - 2.5e-35 122.4 0.3 1.5e-34 119.8 0.1 2.3 3 0 0 3 3 3 1 Aromatic acid exporter family member 2 FUSC_2 PF13515.6 KIY67696.1 - 2e-08 34.4 11.9 2e-08 34.4 11.9 3.9 3 1 0 3 3 3 1 Fusaric acid resistance protein-like DUF3963 PF13124.6 KIY67696.1 - 0.012 15.5 2.4 0.046 13.7 2.4 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3963) Herpes_LMP1 PF05297.11 KIY67696.1 - 0.038 13.2 0.3 0.1 11.8 0.3 1.7 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DUF2244 PF10003.9 KIY67696.1 - 7.7 6.2 7.2 3.8 7.2 0.1 2.8 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) Pkinase PF00069.25 KIY67698.1 - 1.2e-63 214.9 0.0 1.4e-63 214.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY67698.1 - 1.2e-24 87.0 0.0 1.6e-24 86.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY67698.1 - 0.00023 20.6 0.0 0.00048 19.5 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KIY67698.1 - 0.0015 18.5 0.1 0.093 12.6 0.0 2.7 2 1 1 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KIY67698.1 - 0.009 15.6 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase FTA2 PF13095.6 KIY67698.1 - 0.081 12.5 0.0 0.24 11.0 0.0 1.7 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KIY67698.1 - 0.13 11.5 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Hid1 PF12722.7 KIY67699.1 - 1.1e-173 579.5 0.0 1.3e-173 579.3 0.0 1.0 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 KIY67699.1 - 7.8e-85 285.6 0.0 1e-84 285.2 0.0 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein YqgB PF11036.8 KIY67699.1 - 0.058 13.1 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Virulence promoting factor GATA PF00320.27 KIY67700.1 - 2.3e-15 55.9 4.7 5.6e-15 54.6 4.7 1.7 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.12 KIY67700.1 - 0.00074 19.0 0.6 0.0017 17.9 0.6 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding Tyrosinase PF00264.20 KIY67701.1 - 1.1e-51 176.3 2.4 2e-51 175.4 2.4 1.5 1 0 0 1 1 1 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 KIY67701.1 - 3.3e-25 89.1 0.0 5.3e-25 88.4 0.0 1.3 1 0 0 1 1 1 1 Tyosinase C-terminal domain Arylsulfotran_2 PF14269.6 KIY67702.1 - 5.3e-70 236.2 0.7 7.5e-70 235.7 0.7 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KIY67702.1 - 1.5e-14 53.7 0.5 1.7e-13 50.3 0.5 2.3 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Glyco_hydro_63 PF03200.16 KIY67704.1 - 1.7e-157 525.1 0.0 1.7e-156 521.8 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 KIY67704.1 - 1.4e-52 179.0 0.0 4.4e-52 177.4 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 63 N-terminal domain Trehalase PF01204.18 KIY67704.1 - 0.00078 18.4 0.0 0.0012 17.8 0.0 1.2 1 0 0 1 1 1 1 Trehalase Rad51 PF08423.11 KIY67705.1 - 1.1e-24 87.1 0.0 1.3e-24 86.9 0.0 1.1 1 0 0 1 1 1 1 Rad51 AMP-binding PF00501.28 KIY67707.1 - 7.7e-24 84.1 0.0 1e-23 83.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Linker_histone PF00538.19 KIY67708.1 - 1.1e-21 76.9 0.4 5.5e-21 74.7 0.0 2.4 2 1 1 3 3 3 1 linker histone H1 and H5 family Linker_histone PF00538.19 KIY67709.1 - 6.1e-21 74.6 0.0 6.1e-21 74.6 0.0 2.3 2 1 0 2 2 2 1 linker histone H1 and H5 family Adeno_terminal PF02459.15 KIY67709.1 - 0.023 13.1 0.2 0.032 12.6 0.2 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein Nop14 PF04147.12 KIY67710.1 - 0.26 9.4 15.0 0.38 8.9 15.0 1.2 1 0 0 1 1 1 0 Nop14-like family Nop25 PF09805.9 KIY67710.1 - 6 7.3 10.4 22 5.5 0.2 2.6 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) RRM_1 PF00076.22 KIY67711.1 - 1.8e-26 91.7 0.0 3.6e-12 45.9 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PUF PF00806.19 KIY67711.1 - 8.5e-22 75.6 0.0 4.3e-05 23.0 0.0 5.7 5 0 0 5 5 5 5 Pumilio-family RNA binding repeat RRM_occluded PF16842.5 KIY67711.1 - 4.9e-05 23.1 0.0 0.065 13.1 0.0 2.6 2 0 0 2 2 2 2 Occluded RNA-recognition motif Sulfate_transp PF00916.20 KIY67713.1 - 2.4e-118 395.2 13.0 3.1e-118 394.9 13.0 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KIY67713.1 - 9.5e-08 31.7 0.0 1.8e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 KIY67713.1 - 6.7e-05 23.3 14.8 0.00027 21.3 4.0 2.9 2 1 0 2 2 2 2 Molybdate transporter of MFS superfamily STAS_2 PF13466.6 KIY67713.1 - 0.086 13.2 0.0 0.29 11.5 0.0 1.9 1 0 0 1 1 1 0 STAS domain DUF2627 PF11118.8 KIY67713.1 - 2 9.1 6.1 4.1 8.1 0.3 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2627) Yip1 PF04893.17 KIY67714.1 - 0.019 14.7 14.2 0.29 10.8 5.4 2.1 1 1 1 2 2 2 0 Yip1 domain DUF2383 PF09537.10 KIY67716.1 - 0.0011 19.3 3.7 0.19 12.1 0.5 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF2383) bZIP_1 PF00170.21 KIY67716.1 - 0.019 15.1 7.1 0.5 10.5 1.1 2.8 2 1 0 2 2 2 0 bZIP transcription factor YabA PF06156.13 KIY67716.1 - 1.7 9.3 7.0 19 6.0 0.2 2.5 2 0 0 2 2 2 0 Initiation control protein YabA Fib_alpha PF08702.10 KIY67716.1 - 5.1 7.3 6.5 1.7 8.8 0.2 2.6 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family DivIVA PF05103.13 KIY67716.1 - 7.5 6.7 19.8 2.9 8.0 0.4 3.1 3 0 0 3 3 3 0 DivIVA protein HECT PF00632.25 KIY67718.1 - 1e-92 310.9 0.0 1.3e-92 310.5 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 KIY67718.1 - 6.6e-37 125.3 17.0 2.3e-12 46.7 2.2 3.5 3 0 0 3 3 3 3 WW domain C2 PF00168.30 KIY67718.1 - 2.8e-20 72.5 0.1 8.2e-20 71.0 0.1 1.8 1 0 0 1 1 1 1 C2 domain TFIIA PF03153.13 KIY67718.1 - 1.6 8.6 4.4 2.4 8.1 4.4 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pox_MCEL PF03291.16 KIY67719.1 - 1.6e-85 287.1 0.0 2.6e-85 286.5 0.0 1.3 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 KIY67719.1 - 7.6e-14 52.2 0.0 1.7e-13 51.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIY67719.1 - 5.7e-11 42.4 0.0 1e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIY67719.1 - 8.2e-10 39.3 0.0 1.6e-09 38.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIY67719.1 - 1.3e-08 34.9 0.0 1.9e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIY67719.1 - 2.3e-08 34.6 0.0 5.9e-08 33.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KIY67719.1 - 0.003 17.1 0.0 0.007 15.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain NNMT_PNMT_TEMT PF01234.17 KIY67719.1 - 0.014 14.6 0.0 0.024 13.8 0.0 1.3 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family MetW PF07021.12 KIY67719.1 - 0.076 12.6 0.0 0.22 11.1 0.0 1.8 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW Methyltransf_4 PF02390.17 KIY67719.1 - 0.13 11.7 0.0 0.28 10.7 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase F-box-like PF12937.7 KIY67720.1 - 6.3e-06 26.0 0.1 2.1e-05 24.3 0.1 2.0 1 1 0 1 1 1 1 F-box-like Peptidase_M24 PF00557.24 KIY67721.1 - 1.8e-58 197.7 0.0 2.3e-58 197.3 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KIY67721.1 - 8.2e-19 67.5 0.0 1.6e-18 66.6 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Forkhead PF00250.18 KIY67722.1 - 0.0008 19.6 0.0 0.0015 18.8 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain Atg8 PF02991.16 KIY67724.1 - 6e-52 174.2 0.2 7.1e-52 174.0 0.2 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 KIY67724.1 - 3.8e-07 30.4 0.0 4.7e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 G-patch PF01585.23 KIY67725.1 - 8.2e-13 48.0 4.0 2.1e-12 46.7 1.5 2.7 3 0 0 3 3 3 1 G-patch domain RRM_1 PF00076.22 KIY67725.1 - 4.4e-07 29.6 0.8 0.027 14.3 0.1 3.4 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch_2 PF12656.7 KIY67725.1 - 3.5e-05 23.8 1.4 0.00012 22.1 1.4 1.9 1 0 0 1 1 1 1 G-patch domain RED_N PF07808.13 KIY67725.1 - 0.014 14.9 0.1 0.031 13.8 0.1 1.5 1 0 0 1 1 1 0 RED-like protein N-terminal region zf-C2H2 PF00096.26 KIY67725.1 - 0.1 13.1 1.1 0.25 11.9 1.1 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIY67725.1 - 0.15 13.0 1.0 0.38 11.7 1.0 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KIY67725.1 - 0.32 11.3 6.1 0.22 11.9 2.7 2.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding CaATP_NAI PF12515.8 KIY67726.1 - 0.17 11.5 3.1 0.53 9.9 3.1 1.8 1 1 0 1 1 1 0 Ca2+-ATPase N terminal autoinhibitory domain PBP PF01161.20 KIY67727.1 - 1.8e-10 41.3 0.0 2.5e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Metallothio_11 PF02066.15 KIY67727.1 - 0.055 13.7 0.1 0.15 12.2 0.1 1.7 1 0 0 1 1 1 0 Metallothionein family 11 DNA_pol_E_B PF04042.16 KIY67728.1 - 5.4e-30 104.3 0.0 8e-30 103.8 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Pol_alpha_B_N PF08418.10 KIY67728.1 - 7.6e-20 71.9 3.0 2.4e-10 40.8 0.3 2.2 1 1 0 2 2 2 2 DNA polymerase alpha subunit B N-terminal Metallophos_3 PF14582.6 KIY67728.1 - 0.0024 17.2 0.0 0.0087 15.4 0.0 1.7 2 0 0 2 2 2 1 Metallophosphoesterase, calcineurin superfamily Endosulfine PF04667.17 KIY67729.1 - 1.2e-23 83.0 0.1 1.9e-23 82.4 0.1 1.3 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region ABC2_membrane_2 PF12679.7 KIY67731.1 - 0.062 12.6 3.9 0.091 12.0 3.9 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein MFS_1 PF07690.16 KIY67732.1 - 8.4e-28 97.3 42.8 1.6e-27 96.4 33.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily E1-E2_ATPase PF00122.20 KIY67733.1 - 1.6e-40 138.6 15.3 3.1e-30 105.1 0.4 3.2 3 1 1 4 4 4 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 KIY67733.1 - 3.8e-26 91.9 10.1 4.7e-26 91.6 4.0 2.4 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KIY67733.1 - 1.3e-17 64.8 0.2 1.1e-16 61.8 0.2 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KIY67733.1 - 6.8e-16 58.1 0.0 1.3e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KIY67733.1 - 1.8e-11 43.6 0.2 7.2e-11 41.6 0.2 2.2 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KIY67733.1 - 0.00067 19.5 0.7 0.0028 17.4 0.4 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hist_deacetyl PF00850.19 KIY67734.1 - 3.6e-78 263.2 0.7 2.5e-77 260.4 0.0 2.2 2 1 1 3 3 3 1 Histone deacetylase domain Arb2 PF09757.9 KIY67734.1 - 2.5e-24 85.8 0.1 4.8e-24 84.9 0.0 1.5 2 0 0 2 2 2 1 Arb2 domain Rotamase_3 PF13616.6 KIY67736.1 - 1.1e-17 64.6 0.3 2.5e-17 63.5 0.1 1.7 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 KIY67736.1 - 5.8e-15 56.0 1.9 1.1e-14 55.1 0.6 2.0 1 1 1 2 2 2 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 KIY67736.1 - 0.0021 18.9 4.8 0.018 15.8 4.8 2.0 1 1 0 1 1 1 1 PPIC-type PPIASE domain Fungal_trans PF04082.18 KIY67737.1 - 5.9e-19 68.1 0.1 9.7e-19 67.4 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY67737.1 - 1.3e-08 34.8 12.5 2.2e-08 34.1 12.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.13 KIY67737.1 - 0.00075 19.6 0.0 0.0017 18.5 0.0 1.5 1 0 0 1 1 1 1 Gal4-like dimerisation domain Prot_inhib_II PF02428.15 KIY67737.1 - 9.6 6.7 10.0 58 4.2 9.9 2.1 1 1 1 2 2 2 0 Potato type II proteinase inhibitor family Condensation PF00668.20 KIY67738.1 - 9.7e-178 591.5 0.0 2.3e-41 141.9 0.0 5.2 5 0 0 5 5 5 5 Condensation domain AMP-binding PF00501.28 KIY67738.1 - 2.5e-165 550.2 0.0 9.1e-69 232.1 0.0 4.2 3 1 0 3 3 3 3 AMP-binding enzyme PP-binding PF00550.25 KIY67738.1 - 4.1e-55 184.0 2.7 1.6e-12 47.5 0.0 5.9 5 0 0 5 5 5 5 Phosphopantetheine attachment site WES_acyltransf PF03007.16 KIY67738.1 - 2.2e-07 30.9 0.1 0.27 10.9 0.0 5.2 5 0 0 5 5 5 2 Wax ester synthase-like Acyl-CoA acyltransferase domain AMP-binding_C PF13193.6 KIY67738.1 - 7.3e-06 26.9 0.0 0.16 13.0 0.0 3.1 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain DUF1380 PF07128.12 KIY67738.1 - 0.11 12.7 0.4 0.71 10.1 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1380) CX9C PF16860.5 KIY67739.1 - 2e-05 24.5 0.5 0.00018 21.5 0.5 2.0 1 1 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, UPF0203 PF05254.12 KIY67739.1 - 0.0075 16.5 1.2 0.02 15.1 1.2 1.6 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0203) Cmc1 PF08583.10 KIY67739.1 - 0.019 15.0 0.8 0.03 14.4 0.2 1.6 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like ADH_zinc_N PF00107.26 KIY67741.1 - 9.3e-25 87.1 1.5 1.7e-24 86.3 1.5 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KIY67741.1 - 3.7e-18 66.9 0.1 5.6e-18 66.3 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIY67741.1 - 7.9e-09 35.4 0.0 1.9e-08 34.2 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 KIY67741.1 - 0.05 13.5 0.0 0.33 10.9 0.0 2.3 2 1 0 2 2 2 0 N-terminal domain of oxidoreductase UPF0172 PF03665.13 KIY67742.1 - 2.6e-47 161.3 0.0 3.1e-47 161.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) ADH_zinc_N_2 PF13602.6 KIY67743.1 - 6.9e-17 62.7 0.0 1.3e-16 61.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KIY67743.1 - 9.2e-17 61.2 0.4 1.7e-16 60.4 0.4 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIY67743.1 - 5.4e-11 42.3 0.1 9.5e-08 31.9 0.0 2.6 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 KIY67743.1 - 0.0039 17.1 0.0 0.0078 16.1 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase TrkA_N PF02254.18 KIY67743.1 - 0.016 15.4 0.1 0.038 14.2 0.0 1.7 2 0 0 2 2 2 0 TrkA-N domain DeoRC PF00455.22 KIY67743.1 - 0.024 14.6 0.1 0.037 14.0 0.1 1.2 1 0 0 1 1 1 0 DeoR C terminal sensor domain SBP_bac_3 PF00497.20 KIY67743.1 - 0.04 13.4 0.0 0.054 12.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 Abhydrolase_3 PF07859.13 KIY67744.1 - 8.1e-23 81.4 0.0 1e-22 81.1 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KIY67744.1 - 5.4e-11 42.0 0.0 9e-11 41.2 0.0 1.3 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_6 PF12697.7 KIY67744.1 - 0.0061 17.2 0.2 0.013 16.1 0.2 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family MCM PF00493.23 KIY67746.1 - 3.4e-100 333.8 0.0 4.8e-100 333.3 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KIY67746.1 - 2.1e-37 127.8 0.0 3.6e-37 127.0 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KIY67746.1 - 7.2e-26 90.4 1.5 2.6e-25 88.6 0.8 2.5 2 0 0 2 2 2 1 MCM AAA-lid domain MCM2_N PF12619.8 KIY67746.1 - 4.8e-12 46.4 8.9 4.8e-12 46.4 8.9 2.8 4 0 0 4 4 4 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.6 KIY67746.1 - 1e-11 45.3 0.0 3.7e-11 43.5 0.0 1.9 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KIY67746.1 - 9.4e-08 31.7 0.0 5.5e-06 25.9 0.0 2.5 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KIY67746.1 - 2.6e-06 27.5 0.0 6e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KIY67746.1 - 0.00017 21.4 0.1 0.0055 16.6 0.0 2.8 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KIY67746.1 - 0.0028 17.4 0.1 0.026 14.2 0.1 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain SelR PF01641.18 KIY67746.1 - 0.013 15.6 0.2 4.8 7.3 0.1 2.4 2 0 0 2 2 2 0 SelR domain PetN PF03742.14 KIY67747.1 - 0.094 12.6 2.1 0.59 10.1 2.1 2.3 1 1 0 1 1 1 0 PetN ATP_bind_1 PF03029.17 KIY67748.1 - 3e-73 246.5 0.1 4.1e-73 246.1 0.1 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 KIY67748.1 - 7.9e-06 25.5 0.0 0.0026 17.3 0.0 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_24 PF13479.6 KIY67748.1 - 1.8e-05 24.6 0.1 0.00026 20.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KIY67748.1 - 0.00034 20.7 0.0 0.0041 17.2 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KIY67748.1 - 0.00073 19.1 0.1 0.0049 16.4 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_33 PF13671.6 KIY67748.1 - 0.00089 19.4 0.0 0.003 17.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 KIY67748.1 - 0.0015 18.5 0.0 0.0031 17.5 0.0 1.5 1 0 0 1 1 1 1 NACHT domain G-alpha PF00503.20 KIY67748.1 - 0.0016 17.7 0.0 0.076 12.2 0.0 2.5 2 0 0 2 2 2 1 G-protein alpha subunit SRP54 PF00448.22 KIY67748.1 - 0.0019 17.9 0.0 0.51 9.9 0.0 2.7 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain NTPase_1 PF03266.15 KIY67748.1 - 0.0027 17.6 0.0 0.16 11.9 0.0 2.3 2 0 0 2 2 2 1 NTPase cobW PF02492.19 KIY67748.1 - 0.0031 17.1 0.0 2.9 7.4 0.0 2.4 2 1 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain TsaE PF02367.17 KIY67748.1 - 0.011 15.7 0.0 0.034 14.2 0.0 1.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PduV-EutP PF10662.9 KIY67748.1 - 0.015 15.0 0.2 0.69 9.7 0.0 2.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Zeta_toxin PF06414.12 KIY67748.1 - 0.024 13.9 0.2 0.099 11.9 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin NB-ARC PF00931.22 KIY67748.1 - 0.025 13.8 0.0 0.074 12.2 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain AAA_16 PF13191.6 KIY67748.1 - 0.039 14.3 0.0 0.12 12.8 0.0 1.8 2 1 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.6 KIY67748.1 - 0.056 14.0 0.5 0.64 10.6 0.0 2.7 2 1 1 3 3 3 0 AAA domain RsgA_GTPase PF03193.16 KIY67748.1 - 0.09 12.7 0.0 28 4.6 0.0 3.0 3 0 0 3 3 3 0 RsgA GTPase AAA_30 PF13604.6 KIY67748.1 - 0.091 12.5 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KIY67748.1 - 0.11 12.8 0.0 1.1 9.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain Arf PF00025.21 KIY67748.1 - 0.15 11.5 0.0 1 8.8 0.0 2.3 3 0 0 3 3 3 0 ADP-ribosylation factor family KAP_NTPase PF07693.14 KIY67748.1 - 0.16 11.2 0.0 0.4 9.9 0.0 1.9 1 1 0 1 1 1 0 KAP family P-loop domain FtsK_SpoIIIE PF01580.18 KIY67748.1 - 0.35 10.2 2.0 1.9 7.8 0.1 2.6 2 2 0 3 3 3 0 FtsK/SpoIIIE family Pkinase PF00069.25 KIY67749.1 - 8.5e-73 245.0 0.0 9.5e-73 244.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY67749.1 - 2.5e-34 118.7 0.0 3.3e-34 118.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KIY67749.1 - 4.8e-05 22.5 0.2 0.0001 21.4 0.2 1.5 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KIY67749.1 - 0.0037 17.2 1.9 0.0067 16.4 0.2 2.1 3 0 0 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 KIY67749.1 - 0.017 14.4 2.9 0.026 13.9 1.7 1.9 2 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 KIY67749.1 - 0.028 13.5 0.1 0.045 12.8 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Kinase-like PF14531.6 KIY67749.1 - 0.063 12.6 0.0 0.15 11.4 0.0 1.7 2 0 0 2 2 2 0 Kinase-like ADH_zinc_N PF00107.26 KIY67750.1 - 6.8e-25 87.5 0.9 1.2e-24 86.7 0.9 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KIY67750.1 - 1.2e-14 55.5 0.0 2.1e-14 54.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIY67750.1 - 2.2e-08 33.9 0.0 5.2e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 KIY67750.1 - 0.025 13.9 0.1 0.045 13.0 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Cpn10 PF00166.21 KIY67750.1 - 0.2 11.7 1.2 3 7.9 0.1 3.0 4 0 0 4 4 4 0 Chaperonin 10 Kd subunit Metallophos PF00149.28 KIY67751.1 - 2.8e-15 57.4 0.3 3.7e-15 57.0 0.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KIY67751.1 - 2.4e-05 24.6 0.0 4.2e-05 23.8 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 KIY67751.1 - 0.017 14.4 0.0 0.41 9.9 0.0 2.5 2 1 0 2 2 2 0 Metallophosphoesterase, calcineurin superfamily NADH_B2 PF14813.6 KIY67752.1 - 0.0053 16.5 0.0 0.0059 16.4 0.0 1.1 1 0 0 1 1 1 1 NADH dehydrogenase 1 beta subcomplex subunit 2 Oxidored_FMN PF00724.20 KIY67755.1 - 7.3e-61 206.3 0.0 8.9e-61 206.0 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 KIY67755.1 - 0.00046 19.4 0.0 0.00082 18.6 0.0 1.4 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) KAR9 PF08580.10 KIY67756.1 - 2 6.8 5.4 2.5 6.5 5.4 1.3 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Zn_clus PF00172.18 KIY67757.1 - 7.2e-09 35.6 13.1 1.3e-08 34.8 13.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short_C2 PF13561.6 KIY67759.1 - 1e-13 51.4 0.0 1.3e-13 51.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIY67759.1 - 7.7e-12 45.1 0.0 9.9e-12 44.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase DUF2703 PF10865.8 KIY67759.1 - 0.086 13.0 0.5 0.18 12.0 0.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF2703) DUF1776 PF08643.10 KIY67759.1 - 0.089 12.1 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) DUF3235 PF11574.8 KIY67759.1 - 0.096 13.6 0.0 0.13 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3235) MFS_1 PF07690.16 KIY67760.1 - 7.3e-39 133.7 38.8 1.3e-38 132.8 37.9 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIY67760.1 - 2.8e-09 36.4 10.3 2.8e-09 36.4 10.3 3.2 3 1 0 3 3 3 1 Sugar (and other) transporter Pkinase_fungal PF17667.1 KIY67762.1 - 2.8e-10 39.6 0.0 3.4e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase DnaJ PF00226.31 KIY67763.1 - 6e-18 64.7 0.1 8e-18 64.3 0.1 1.2 1 0 0 1 1 1 1 DnaJ domain CTP_transf_1 PF01148.20 KIY67764.1 - 0.032 14.0 3.0 0.053 13.3 3.0 1.4 1 1 0 1 1 1 0 Cytidylyltransferase family YjbE PF11106.8 KIY67764.1 - 0.31 11.3 11.1 0.39 11.0 1.4 2.8 2 0 0 2 2 2 0 Exopolysaccharide production protein YjbE Cpn60_TCP1 PF00118.24 KIY67768.1 - 5.2e-81 272.7 11.9 1.9e-80 270.9 11.9 1.7 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Pho88 PF10032.9 KIY67769.1 - 5.5e-66 221.3 0.0 6.2e-66 221.1 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) DUF2156 PF09924.9 KIY67770.1 - 1e-14 54.3 0.0 1.5e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) SMC_ScpB PF04079.16 KIY67770.1 - 0.027 14.1 0.0 0.045 13.4 0.0 1.3 1 0 0 1 1 1 0 Segregation and condensation complex subunit ScpB Pinin_SDK_memA PF04696.13 KIY67771.1 - 2.8e-12 46.8 0.6 2.8e-12 46.8 0.6 2.1 1 1 1 2 2 2 1 pinin/SDK/memA/ protein conserved region ADH_zinc_N PF00107.26 KIY67772.1 - 8.8e-19 67.8 0.0 1.4e-18 67.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KIY67772.1 - 3.8e-18 65.3 0.0 7.7e-18 64.4 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 KIY67772.1 - 0.00011 23.3 0.0 0.0002 22.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase SET PF00856.28 KIY67773.1 - 3.8e-10 40.4 0.0 3.9e-09 37.1 0.0 2.6 2 1 0 2 2 2 1 SET domain TPR_2 PF07719.17 KIY67773.1 - 8.3 6.8 7.1 9 6.7 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat PH PF00169.29 KIY67774.1 - 1.5e-05 25.5 0.0 2.8e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 PH domain FA_desaturase PF00487.24 KIY67775.1 - 9e-21 74.9 27.7 9e-21 74.9 27.7 2.1 1 1 1 2 2 2 1 Fatty acid desaturase DUF3474 PF11960.8 KIY67775.1 - 0.14 12.3 0.1 0.3 11.3 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) FA_desaturase PF00487.24 KIY67776.1 - 7e-22 78.5 36.5 8.6e-22 78.2 35.8 1.4 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 KIY67776.1 - 0.022 15.0 0.0 0.044 14.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) FGGY_C PF02782.16 KIY67776.1 - 0.094 12.4 0.1 0.22 11.2 0.0 1.6 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain DUF3089 PF11288.8 KIY67777.1 - 0.064 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Peptidase_S11 PF00768.20 KIY67777.1 - 0.1 12.0 0.1 1.4 8.3 0.0 2.1 2 0 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase Aldo_ket_red PF00248.21 KIY67778.1 - 5.3e-48 163.7 0.0 6e-48 163.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF1719 PF08224.11 KIY67778.1 - 0.11 11.6 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1719) SET PF00856.28 KIY67780.1 - 4.1e-09 37.0 0.0 3.1e-08 34.2 0.0 2.3 1 1 0 1 1 1 1 SET domain Polyketide_cyc2 PF10604.9 KIY67781.1 - 3.8e-05 24.0 0.1 0.00013 22.2 0.1 1.8 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 KIY67781.1 - 0.00046 20.4 0.0 0.00073 19.8 0.0 1.5 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 KIY67782.1 - 4.6e-05 23.7 0.0 8.4e-05 22.9 0.0 1.5 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 KIY67782.1 - 5.1e-05 23.5 0.1 9.1e-05 22.7 0.1 1.4 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport SRP_TPR_like PF17004.5 KIY67783.1 - 0.00016 21.7 0.0 0.00048 20.1 0.0 1.7 1 1 0 1 1 1 1 Putative TPR-like repeat SRP72 PF08492.12 KIY67783.1 - 0.0007 20.0 1.6 0.0058 17.0 0.1 2.4 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_6 PF13174.6 KIY67783.1 - 0.016 15.8 0.0 0.038 14.6 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 KIY67783.1 - 0.11 12.7 0.2 0.34 11.1 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-C2H2_4 PF13894.6 KIY67785.1 - 1.3 10.1 7.6 0.89 10.6 1.0 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger Trp_halogenase PF04820.14 KIY67786.1 - 5.4e-05 22.2 0.2 0.013 14.4 0.0 3.0 3 0 0 3 3 3 2 Tryptophan halogenase FAD_oxidored PF12831.7 KIY67786.1 - 0.0074 15.7 0.3 0.4 10.0 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Cellulase PF00150.18 KIY67787.1 - 3.5e-10 39.8 0.1 3.5e-10 39.8 0.1 1.8 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) T3SS_needle_E PF08988.10 KIY67787.1 - 0.13 12.5 0.1 0.29 11.3 0.0 1.6 2 0 0 2 2 2 0 Type III secretion system, cytoplasmic E component of needle Pkinase PF00069.25 KIY67788.1 - 4.2e-67 226.3 0.0 5e-67 226.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY67788.1 - 2.8e-31 108.8 0.0 3.8e-31 108.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KIY67788.1 - 0.00046 19.6 0.2 0.00077 18.9 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KIY67788.1 - 0.00073 18.9 0.0 0.0013 18.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KIY67788.1 - 0.007 15.4 0.0 0.01 14.8 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KIY67788.1 - 0.061 13.2 1.2 0.34 10.8 0.4 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KIY67788.1 - 0.12 11.4 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Ammonium_transp PF00909.21 KIY67790.1 - 4.9e-114 381.1 27.2 5.6e-114 380.9 27.2 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family zf-LITAF-like PF10601.9 KIY67790.1 - 5.4 7.4 6.8 3.1e+02 1.7 0.0 4.6 5 0 0 5 5 5 0 LITAF-like zinc ribbon domain Zn_clus PF00172.18 KIY67791.1 - 1.3e-05 25.3 9.1 2.2e-05 24.5 9.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.25 KIY67791.1 - 0.013 15.5 0.0 0.036 14.1 0.0 1.7 1 0 0 1 1 1 0 PAS fold HLH PF00010.26 KIY67793.1 - 5e-11 42.4 0.1 1e-10 41.4 0.1 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain THOC7 PF05615.13 KIY67793.1 - 0.035 14.4 2.2 0.054 13.8 2.2 1.4 1 1 0 1 1 1 0 Tho complex subunit 7 DivIC PF04977.15 KIY67793.1 - 0.15 11.9 0.2 0.36 10.6 0.0 1.7 2 0 0 2 2 2 0 Septum formation initiator Ras PF00071.22 KIY67794.1 - 2.8e-55 186.4 0.0 3.2e-55 186.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIY67794.1 - 1.1e-22 80.5 0.0 1.5e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIY67794.1 - 4.8e-07 29.4 0.0 8e-07 28.7 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KIY67794.1 - 0.0021 17.5 0.0 0.0031 17.0 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KIY67794.1 - 0.19 11.0 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region SET PF00856.28 KIY67795.1 - 4.3e-11 43.5 0.0 3.5e-10 40.5 0.0 2.5 1 1 0 1 1 1 1 SET domain TPR_11 PF13414.6 KIY67795.1 - 0.085 12.6 0.0 0.3 10.8 0.0 2.0 1 0 0 1 1 1 0 TPR repeat TPR_2 PF07719.17 KIY67795.1 - 0.25 11.5 0.0 0.25 11.5 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Smr PF01713.21 KIY67796.1 - 2.3e-07 31.0 0.1 6.8e-07 29.6 0.1 1.8 1 0 0 1 1 1 1 Smr domain DUF1771 PF08590.10 KIY67796.1 - 0.00042 20.6 3.9 0.00087 19.6 3.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) DUF2015 PF09435.10 KIY67797.1 - 3.1e-36 123.6 0.0 3.7e-36 123.4 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) FHA PF00498.26 KIY67798.1 - 1.5e-14 54.1 0.0 2.2e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KIY67798.1 - 6.8e-06 26.3 0.0 1.1e-05 25.6 0.0 1.3 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain DUF5127 PF17168.4 KIY67800.1 - 1.6e-57 194.9 0.9 3.1e-57 194.0 0.9 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF1793 PF08760.11 KIY67800.1 - 8.9e-31 107.6 1.4 2e-30 106.5 1.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF4965 PF16335.5 KIY67800.1 - 7e-26 90.9 0.3 1.6e-25 89.7 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4965) NolB PF17398.2 KIY67801.1 - 0.057 13.8 0.3 0.71 10.3 0.1 2.6 2 0 0 2 2 2 0 Nodulation protein NolB Pkinase_Tyr PF07714.17 KIY67802.1 - 3.3e-24 85.6 0.0 3.9e-24 85.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIY67802.1 - 2.3e-17 63.2 0.0 2.8e-17 63.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KIY67802.1 - 0.14 12.1 0.2 0.19 11.6 0.2 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Epimerase PF01370.21 KIY67803.1 - 3.9e-10 39.6 0.0 7.2e-06 25.6 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KIY67803.1 - 1.3e-05 25.2 0.1 3e-05 24.0 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KIY67803.1 - 4.9e-05 22.5 0.0 0.001 18.1 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KIY67803.1 - 0.00041 19.8 0.0 0.0007 19.1 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KIY67803.1 - 0.00076 19.1 0.0 0.0011 18.5 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 KIY67803.1 - 0.097 11.8 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein DXP_reductoisom PF02670.16 KIY67803.1 - 0.18 12.5 0.0 0.29 11.8 0.0 1.3 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase LVIVD PF08309.11 KIY67804.1 - 0.12 11.7 0.0 0.28 10.5 0.0 1.6 1 0 0 1 1 1 0 LVIVD repeat Pkinase_Tyr PF07714.17 KIY67806.1 - 3.9e-36 124.7 0.0 5.1e-36 124.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIY67806.1 - 4.3e-32 111.5 0.0 6e-32 111.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KIY67806.1 - 0.0067 15.8 0.0 0.01 15.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KIY67806.1 - 0.011 15.0 0.1 0.019 14.3 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KIY67806.1 - 0.043 12.6 0.1 0.07 11.9 0.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 KIY67806.1 - 0.054 13.4 0.4 0.11 12.4 0.4 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 KIY67806.1 - 0.19 11.3 0.0 0.35 10.4 0.0 1.4 1 0 0 1 1 1 0 RIO1 family NMO PF03060.15 KIY67807.1 - 2.4e-48 165.3 0.2 3.6e-48 164.6 0.2 1.3 1 1 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.18 KIY67807.1 - 0.00012 21.2 1.8 0.00017 20.8 1.8 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 KIY67807.1 - 0.00025 20.2 0.6 0.00025 20.2 0.6 1.7 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain Cyto_heme_lyase PF01265.17 KIY67808.1 - 1.3e-50 172.7 6.4 2.4e-49 168.5 6.4 2.0 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase zf-H2C2_5 PF13909.6 KIY67809.1 - 0.0052 16.5 4.2 0.012 15.4 4.2 1.6 1 0 0 1 1 1 1 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 KIY67809.1 - 0.035 14.6 4.8 0.035 14.6 4.8 2.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIY67809.1 - 0.05 14.5 3.4 0.16 12.8 3.4 2.0 1 0 0 1 1 1 0 C2H2-type zinc finger Forkhead PF00250.18 KIY67811.1 - 3.9e-15 55.9 0.0 7.1e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain zf-C2H2 PF00096.26 KIY67811.1 - 5.2e-05 23.5 18.7 0.0018 18.6 0.8 4.0 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIY67811.1 - 8e-05 23.1 15.9 0.0062 17.3 0.5 4.2 4 0 0 4 4 4 2 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KIY67811.1 - 0.0051 16.5 8.3 0.036 13.8 0.1 3.4 3 0 0 3 3 3 2 C2H2-type zinc-finger domain zf-C2HE PF16278.5 KIY67811.1 - 0.027 14.9 0.2 0.086 13.3 0.2 1.8 1 0 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_2 PF12756.7 KIY67811.1 - 0.51 10.7 3.1 25 5.3 0.0 3.2 3 0 0 3 3 3 0 C2H2 type zinc-finger (2 copies) Ribosomal_L16 PF00252.18 KIY67813.1 - 0.02 14.9 0.1 0.025 14.6 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein L16p/L10e L27 PF02828.16 KIY67813.1 - 0.03 14.1 0.1 9.1 6.1 0.0 2.3 2 0 0 2 2 2 0 L27 domain Cofilin_ADF PF00241.20 KIY67814.1 - 0.017 15.0 0.0 0.035 13.9 0.0 1.6 1 0 0 1 1 1 0 Cofilin/tropomyosin-type actin-binding protein PH PF00169.29 KIY67814.1 - 0.028 14.9 0.7 0.11 13.1 0.1 2.3 2 0 0 2 2 2 0 PH domain Macoilin PF09726.9 KIY67814.1 - 0.053 12.1 13.5 0.066 11.8 13.5 1.1 1 0 0 1 1 1 0 Macoilin family p450 PF00067.22 KIY67815.1 - 7.1e-72 242.6 0.0 1.7e-71 241.4 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 SRI PF08236.11 KIY67815.1 - 0.15 12.2 0.4 0.35 11.1 0.4 1.5 1 0 0 1 1 1 0 SRI (Set2 Rpb1 interacting) domain p450 PF00067.22 KIY67816.1 - 5.9e-70 236.3 0.0 1.4e-69 235.0 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Oxidored_FMN PF00724.20 KIY67817.1 - 3e-104 349.0 0.0 3.5e-104 348.8 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DPPIV_N PF00930.21 KIY67818.1 - 1.7e-106 356.0 2.4 2.3e-106 355.6 2.4 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 KIY67818.1 - 1.2e-45 155.6 2.5 1.8e-45 155.0 2.5 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 KIY67818.1 - 1.5e-05 24.7 4.4 5.5e-05 22.9 4.2 2.0 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.7 KIY67818.1 - 0.0014 19.2 0.5 0.0041 17.8 0.5 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 KIY67818.1 - 0.0016 18.3 0.0 0.0029 17.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 KIY67818.1 - 0.0035 17.0 0.2 0.0074 16.0 0.1 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold AXE1 PF05448.12 KIY67818.1 - 0.013 14.2 0.1 0.021 13.5 0.1 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) COesterase PF00135.28 KIY67818.1 - 0.025 13.5 0.1 0.036 12.9 0.1 1.1 1 0 0 1 1 1 0 Carboxylesterase family PD40 PF07676.12 KIY67818.1 - 0.051 13.5 2.9 1.2 9.2 0.1 3.3 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat DLH PF01738.18 KIY67818.1 - 0.15 11.6 0.0 0.29 10.6 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family LRR_6 PF13516.6 KIY67819.1 - 0.077 13.1 0.2 3.1 8.1 0.0 2.8 2 0 0 2 2 2 0 Leucine Rich repeat LRR_4 PF12799.7 KIY67819.1 - 0.11 13.0 4.6 51 4.5 0.1 4.2 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KIY67819.1 - 0.11 12.3 2.1 1.8 8.4 0.0 3.1 3 0 0 3 3 3 0 Leucine rich repeat FXR_C1 PF16096.5 KIY67820.1 - 0.037 14.2 2.9 0.069 13.4 2.9 1.4 1 0 0 1 1 1 0 Fragile X-related 1 protein C-terminal region 2 DUF4680 PF15730.5 KIY67820.1 - 0.084 13.2 3.5 0.14 12.5 3.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4680) DUF4257 PF14074.6 KIY67821.1 - 0.096 12.9 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4257) DUF2063 PF09836.9 KIY67821.1 - 0.13 12.5 0.0 0.24 11.7 0.0 1.4 1 0 0 1 1 1 0 Putative DNA-binding domain Prefoldin PF02996.17 KIY67822.1 - 5.5e-27 94.1 0.2 8.8e-27 93.4 0.1 1.4 1 1 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 KIY67822.1 - 0.021 14.8 4.6 0.42 10.6 0.1 2.2 2 0 0 2 2 2 0 Prefoldin subunit Fib_alpha PF08702.10 KIY67822.1 - 0.027 14.7 1.2 2.5 8.3 0.1 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 KIY67822.1 - 0.028 14.4 2.4 4 7.5 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Cep57_MT_bd PF06657.13 KIY67822.1 - 0.049 14.1 3.7 0.063 13.7 0.5 2.2 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Ntox28 PF15605.6 KIY67822.1 - 0.052 13.8 0.4 6.5 7.1 0.1 2.1 2 0 0 2 2 2 0 Bacterial toxin 28 TACC_C PF05010.14 KIY67822.1 - 0.055 13.3 5.0 0.41 10.4 1.4 2.1 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal TMF_TATA_bd PF12325.8 KIY67822.1 - 0.1 12.8 0.5 0.1 12.8 0.5 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding COG2 PF06148.11 KIY67822.1 - 0.12 12.4 1.9 3.6 7.7 0.1 2.2 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DHR10 PF18595.1 KIY67822.1 - 0.14 12.2 4.1 0.5 10.4 0.8 2.3 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain Baculo_PEP_C PF04513.12 KIY67822.1 - 0.16 12.0 5.0 4.9 7.2 0.6 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus FlaC_arch PF05377.11 KIY67822.1 - 1 9.8 4.5 2.5 8.6 0.3 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) GAS PF13851.6 KIY67822.1 - 1.4 8.2 7.6 0.53 9.6 1.9 2.0 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding GIT_CC PF16559.5 KIY67822.1 - 6.7 6.7 9.5 2.3 8.2 1.8 2.7 2 1 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor PRiA4_ORF3 PF07929.11 KIY67823.1 - 1.4e-28 99.8 0.0 4.1e-28 98.2 0.0 1.7 1 1 0 1 1 1 1 Plasmid pRiA4b ORF-3-like protein zf-MYND PF01753.18 KIY67823.1 - 2.2e-07 30.8 15.6 3.7e-07 30.1 15.6 1.4 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KIY67823.1 - 0.013 15.8 12.8 0.023 15.0 12.8 1.5 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-HIT PF04438.16 KIY67823.1 - 2 8.3 8.7 4.7 7.2 8.7 1.6 1 0 0 1 1 1 0 HIT zinc finger Abhydrolase_3 PF07859.13 KIY67824.1 - 4.8e-11 42.9 0.0 6.5e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KIY67824.1 - 7.8e-10 38.1 0.0 1.2e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_3 PF07859.13 KIY67825.1 - 1.1e-13 51.6 0.0 1.5e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KIY67825.1 - 4.7e-08 32.3 0.0 7.5e-08 31.6 0.0 1.3 1 0 0 1 1 1 1 Steryl acetyl hydrolase bZIP_2 PF07716.15 KIY67826.1 - 4e-07 30.0 6.0 6e-07 29.5 6.0 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KIY67826.1 - 0.018 15.2 4.1 0.028 14.5 4.1 1.2 1 0 0 1 1 1 0 bZIP transcription factor FAM199X PF15814.5 KIY67826.1 - 0.068 12.2 3.0 0.081 12.0 3.0 1.1 1 0 0 1 1 1 0 Protein family FAM199X CCDC-167 PF15188.6 KIY67826.1 - 0.087 13.2 3.7 0.12 12.7 3.7 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 PTN13_u3 PF16599.5 KIY67826.1 - 0.16 12.0 4.1 0.21 11.6 4.1 1.1 1 0 0 1 1 1 0 Unstructured linker region on PTN13 protein between PDZ IMUP PF15761.5 KIY67826.1 - 2.1 9.1 6.7 1.9 9.2 5.6 1.4 1 1 0 1 1 1 0 Immortalisation up-regulated protein Gtr1_RagA PF04670.12 KIY67827.1 - 1.4e-85 286.4 0.1 1.7e-85 286.1 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.22 KIY67827.1 - 5.9e-08 32.5 0.0 8.7e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIY67827.1 - 1.1e-07 32.1 0.0 2.1e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIY67827.1 - 5.8e-07 29.1 0.0 8.4e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KIY67827.1 - 4.7e-06 26.7 0.0 7.8e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KIY67827.1 - 0.0042 16.5 0.0 0.0066 15.9 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 KIY67827.1 - 0.027 14.2 0.0 0.17 11.6 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 KIY67827.1 - 0.11 12.2 0.1 0.23 11.2 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KIY67827.1 - 0.13 11.7 0.2 0.53 9.8 0.1 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region RsgA_GTPase PF03193.16 KIY67827.1 - 0.18 11.7 0.3 3.4 7.5 0.1 2.5 2 1 0 2 2 2 0 RsgA GTPase G-alpha PF00503.20 KIY67827.1 - 0.46 9.6 1.6 8.3 5.4 0.4 2.4 1 1 0 2 2 2 0 G-protein alpha subunit Pkinase PF00069.25 KIY67828.1 - 3.4e-26 92.2 0.0 4.7e-26 91.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY67828.1 - 1.4e-09 37.6 0.0 7.5e-06 25.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 KIY67828.1 - 0.0035 16.7 0.0 0.0051 16.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIY67828.1 - 0.0041 17.1 0.1 0.0061 16.5 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Oxidored_FMN PF00724.20 KIY67829.1 - 4.5e-102 341.8 0.0 5.1e-102 341.6 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Oxidored_FMN PF00724.20 KIY67830.1 - 1.7e-96 323.4 0.0 2e-96 323.3 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AF-4 PF05110.13 KIY67831.1 - 0.0069 14.6 10.1 0.0092 14.1 10.1 1.0 1 0 0 1 1 1 1 AF-4 proto-oncoprotein Zn_clus PF00172.18 KIY67831.1 - 0.053 13.7 10.2 0.5 10.5 0.6 2.4 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box-like PF12937.7 KIY67832.1 - 0.0011 18.8 2.0 0.0027 17.6 0.3 2.5 2 1 0 2 2 2 1 F-box-like Peptidase_M24 PF00557.24 KIY67833.1 - 2.8e-44 151.3 0.0 4e-44 150.8 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 KIY67833.1 - 1.6e-05 25.6 0.0 2.5e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain HSP20 PF00011.21 KIY67834.1 - 0.00046 20.3 0.0 0.0073 16.4 0.0 2.2 2 0 0 2 2 2 1 Hsp20/alpha crystallin family 2OG-FeII_Oxy_2 PF13532.6 KIY67841.1 - 7.2e-22 78.5 0.0 1.1e-21 78.0 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Rrn6 PF10214.9 KIY67841.1 - 2.2 6.7 11.3 3.1 6.2 11.3 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor PAC4 PF16093.5 KIY67843.1 - 3.4e-19 68.8 0.1 4e-19 68.6 0.1 1.1 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 gpW PF02831.15 KIY67846.1 - 0.061 13.2 0.1 0.83 9.6 0.1 2.3 2 0 0 2 2 2 0 gpW aGPT-Pplase2 PF18724.1 KIY67846.1 - 0.095 12.5 0.0 3.9 7.2 0.0 2.2 2 0 0 2 2 2 0 Alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 2 ERG4_ERG24 PF01222.17 KIY67847.1 - 2.4e-126 422.0 9.1 2.7e-126 421.8 9.1 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 KIY67847.1 - 1.2e-05 24.9 0.1 4.1e-05 23.2 0.1 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.13 KIY67847.1 - 4.9e-05 23.7 1.7 0.0003 21.1 0.0 3.1 3 0 0 3 3 3 1 Phospholipid methyltransferase DctQ PF04290.12 KIY67847.1 - 0.0035 17.2 3.0 0.0035 17.2 3.0 2.5 2 0 0 2 2 2 1 Tripartite ATP-independent periplasmic transporters, DctQ component ICMT PF04140.14 KIY67847.1 - 0.012 16.0 2.6 0.014 15.8 0.0 2.5 3 0 0 3 3 3 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family G-alpha PF00503.20 KIY67848.1 - 5.6e-114 381.0 0.2 6.9e-114 380.7 0.2 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KIY67848.1 - 2.4e-15 56.4 0.5 7.3e-10 38.6 0.1 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 KIY67848.1 - 0.00073 19.8 0.3 0.13 12.4 0.1 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 KIY67848.1 - 0.00074 18.9 0.1 1.1 8.6 0.0 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region CPT PF07931.12 KIY67848.1 - 0.022 14.6 0.1 2 8.2 0.1 2.3 1 1 1 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_29 PF13555.6 KIY67848.1 - 0.052 13.3 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain CHAT PF12770.7 KIY67849.1 - 2.9e-33 115.5 0.0 4.4e-33 114.9 0.0 1.2 1 0 0 1 1 1 1 CHAT domain DUF2267 PF10025.9 KIY67849.1 - 0.0061 16.8 1.3 0.31 11.3 0.0 3.0 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2267) Ank_4 PF13637.6 KIY67849.1 - 0.0078 16.8 0.2 0.073 13.7 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KIY67849.1 - 0.088 13.2 0.0 0.28 11.5 0.0 1.9 1 0 0 1 1 1 0 Ankyrin repeats (many copies) TPR_16 PF13432.6 KIY67849.1 - 7.7 7.3 9.4 0.26 12.0 0.6 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Ank_4 PF13637.6 KIY67850.1 - 7e-18 64.7 0.0 1.2e-07 32.1 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KIY67850.1 - 1e-17 64.5 0.1 1.2e-16 61.1 0.1 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KIY67850.1 - 7.8e-17 61.1 0.9 1.2e-06 28.7 0.0 2.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KIY67850.1 - 3.1e-16 59.0 0.4 0.0011 19.3 0.0 3.0 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 KIY67850.1 - 5.5e-14 50.9 0.0 0.0012 19.2 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Glyco_hydro_16 PF00722.21 KIY67851.1 - 6.6e-07 29.0 0.0 3.8e-06 26.5 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 DUF1372 PF07116.11 KIY67852.1 - 0.14 12.4 0.0 0.28 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1372) Sugar_tr PF00083.24 KIY67855.1 - 1.1e-34 120.2 23.1 1.8e-34 119.4 23.1 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY67855.1 - 2.6e-30 105.5 34.2 2.2e-24 86.1 18.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Amino_oxidase PF01593.24 KIY67857.1 - 4.4e-31 108.7 0.0 5.9e-31 108.2 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KIY67857.1 - 2.2e-11 43.8 1.7 3.1e-11 43.3 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KIY67857.1 - 1.7e-06 27.8 0.0 0.00037 20.2 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIY67857.1 - 0.00081 18.7 0.0 0.82 8.8 0.0 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIY67857.1 - 0.0014 19.1 0.1 2.1 9.0 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KIY67857.1 - 0.0021 17.3 0.8 0.0027 17.0 0.0 1.5 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.6 KIY67857.1 - 0.073 13.1 0.0 0.073 13.1 0.0 2.3 3 0 0 3 3 3 0 FAD-NAD(P)-binding MCRA PF06100.11 KIY67857.1 - 0.18 10.5 0.0 0.3 9.8 0.0 1.4 1 0 0 1 1 1 0 MCRA family Suc_Fer-like PF06999.12 KIY67860.1 - 6e-27 94.8 0.0 7e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Flagellin_N PF00669.20 KIY67861.1 - 0.037 14.1 5.0 0.056 13.6 4.6 1.4 1 1 0 1 1 1 0 Bacterial flagellin N-terminal helical region PE PF00934.20 KIY67861.1 - 0.14 12.5 0.7 0.14 12.5 0.7 2.6 1 1 2 3 3 3 0 PE family FIVAR PF07554.13 KIY67861.1 - 3.7 8.4 8.7 2 9.2 1.7 2.2 1 1 1 2 2 2 0 FIVAR domain DUF4203 PF13886.6 KIY67864.1 - 0.00031 20.5 20.3 0.00059 19.6 20.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) TFIIE_alpha PF02002.17 KIY67866.1 - 3.7e-18 65.3 0.6 3.7e-18 65.3 0.6 1.9 2 0 0 2 2 2 1 TFIIE alpha subunit TFIIE-A_C PF11521.8 KIY67866.1 - 9.3e-06 25.9 2.1 2.9e-05 24.3 0.5 2.6 2 0 0 2 2 2 1 C-terminal general transcription factor TFIIE alpha TF_Zn_Ribbon PF08271.12 KIY67866.1 - 0.00016 21.1 1.4 0.00038 19.9 1.4 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding RecO_N_2 PF13114.6 KIY67866.1 - 0.0013 18.4 0.1 0.0028 17.3 0.1 1.5 1 0 0 1 1 1 1 RecO N terminal Zn_ribbon_SprT PF17283.2 KIY67866.1 - 0.006 16.5 0.1 0.016 15.1 0.1 1.7 1 0 0 1 1 1 1 SprT-like zinc ribbon domain zf-TFIIIC PF12660.7 KIY67866.1 - 0.065 13.2 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Putative zinc-finger of transcription factor IIIC complex Rrf2 PF02082.20 KIY67866.1 - 0.13 12.7 0.0 0.32 11.4 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator MarR_2 PF12802.7 KIY67866.1 - 0.14 12.0 0.0 0.79 9.7 0.0 2.3 2 0 0 2 2 2 0 MarR family HTH_Crp_2 PF13545.6 KIY67866.1 - 0.15 12.1 0.0 0.34 10.9 0.0 1.6 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain zf-MYND PF01753.18 KIY67867.1 - 5.7e-06 26.3 13.3 1.7e-05 24.8 13.3 1.9 1 1 0 1 1 1 1 MYND finger MFS_1 PF07690.16 KIY67869.1 - 2.4e-35 122.1 26.1 2.4e-35 122.1 26.1 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 KIY67869.1 - 5.2e-06 26.0 9.3 8.5e-06 25.3 9.3 1.3 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB TRI12 PF06609.13 KIY67869.1 - 1.7e-05 23.5 3.5 2.5e-05 22.9 3.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 KIY67869.1 - 0.037 12.3 4.4 0.013 13.8 1.2 1.8 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Glyco_hydro_16 PF00722.21 KIY67871.1 - 8.6e-07 28.6 0.0 1.9e-06 27.5 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 SPX PF03105.19 KIY67872.1 - 3.8 7.3 15.7 7.4 6.4 15.7 1.5 1 1 0 1 1 1 0 SPX domain Fungal_trans PF04082.18 KIY67873.1 - 6.5e-29 100.8 0.0 1.3e-28 99.8 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY67873.1 - 5.6e-08 32.8 8.0 1.1e-07 31.9 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cpn60_TCP1 PF00118.24 KIY67874.1 - 1.1e-146 489.4 0.6 1.2e-146 489.2 0.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family EAL PF00563.20 KIY67874.1 - 0.087 12.3 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 EAL domain ABC2_membrane PF01061.24 KIY67875.1 - 1.3e-69 233.8 49.6 4.5e-39 134.0 21.5 2.9 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KIY67875.1 - 2.8e-38 131.5 0.0 3.4e-18 66.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KIY67875.1 - 3.6e-33 113.3 1.5 3.8e-26 90.8 0.0 3.3 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.6 KIY67875.1 - 1e-10 42.1 0.0 3.2e-10 40.5 0.0 1.9 1 0 0 1 1 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 KIY67875.1 - 3.6e-10 39.5 28.0 1.9e-07 30.5 11.4 3.0 2 1 0 3 3 3 2 ABC-2 family transporter protein AAA_16 PF13191.6 KIY67875.1 - 1.5e-06 28.7 0.1 0.0023 18.3 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KIY67875.1 - 2.6e-06 27.4 0.2 3.9e-05 23.6 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_33 PF13671.6 KIY67875.1 - 5.4e-05 23.4 0.1 0.42 10.8 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.6 KIY67875.1 - 0.0001 22.6 0.2 0.15 12.3 0.2 3.0 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KIY67875.1 - 0.00022 21.7 0.0 0.021 15.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KIY67875.1 - 0.00039 20.1 1.0 0.13 12.1 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_28 PF13521.6 KIY67875.1 - 0.00089 19.5 0.8 0.088 13.0 0.8 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KIY67875.1 - 0.0017 18.3 0.2 1.6 8.7 0.2 2.7 3 0 0 3 3 3 1 NACHT domain AAA_25 PF13481.6 KIY67875.1 - 0.0025 17.4 0.4 0.022 14.3 0.2 2.2 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KIY67875.1 - 0.0026 17.8 0.6 0.91 9.6 0.3 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_21 PF13304.6 KIY67875.1 - 0.0031 17.4 0.0 0.3 10.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_17 PF13207.6 KIY67875.1 - 0.0065 16.9 0.1 1.6 9.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 KIY67875.1 - 0.011 15.2 0.0 1.1 8.7 0.0 3.0 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain dNK PF01712.19 KIY67875.1 - 0.012 15.4 0.0 3.7 7.3 0.0 2.3 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA_30 PF13604.6 KIY67875.1 - 0.017 14.8 0.1 0.51 10.0 0.1 2.3 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 KIY67875.1 - 0.1 12.0 0.6 7 5.9 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family Ploopntkinase3 PF18751.1 KIY67875.1 - 0.1 12.5 0.1 2.8 7.8 0.0 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 RNA_helicase PF00910.22 KIY67875.1 - 0.11 12.9 0.1 20 5.6 0.0 2.7 2 0 0 2 2 2 0 RNA helicase T2SSE PF00437.20 KIY67875.1 - 0.22 10.5 0.2 20 4.1 0.2 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein TsaE PF02367.17 KIY67875.1 - 0.24 11.4 1.2 1.8 8.6 0.2 2.5 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 KIY67875.1 - 0.25 10.6 0.6 3.1 7.0 0.4 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_24 PF13479.6 KIY67875.1 - 0.26 11.0 0.5 6 6.5 0.4 2.3 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 KIY67875.1 - 0.65 10.3 1.9 28 5.0 0.0 3.5 4 0 0 4 4 3 0 Putative exonuclease SbcCD, C subunit cobW PF02492.19 KIY67875.1 - 0.87 9.2 3.7 1.6 8.3 1.2 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain UQ_con PF00179.26 KIY67876.1 - 8.2e-53 177.8 0.0 9.2e-53 177.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KIY67876.1 - 0.0068 16.7 0.0 0.0079 16.5 0.0 1.2 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 KIY67876.1 - 0.021 14.6 0.0 0.024 14.3 0.0 1.1 1 0 0 1 1 1 0 Prokaryotic E2 family B UEV PF05743.13 KIY67876.1 - 0.041 13.7 0.0 0.063 13.1 0.0 1.3 1 0 0 1 1 1 0 UEV domain KR PF08659.10 KIY67877.1 - 0.00011 22.2 0.0 0.0002 21.3 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 KIY67877.1 - 0.001 18.6 0.0 0.002 17.6 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Cytochrom_B561 PF03188.16 KIY67878.1 - 0.025 14.7 0.8 0.025 14.7 0.8 2.3 2 1 0 2 2 2 0 Eukaryotic cytochrome b561 Zn_clus PF00172.18 KIY67879.1 - 3e-08 33.7 11.0 4.9e-08 33.0 11.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KIY67880.1 - 8.3e-30 103.7 0.0 1.5e-29 102.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY67880.1 - 8e-07 29.1 11.8 1.5e-06 28.2 11.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain KAR9 PF08580.10 KIY67880.1 - 0.17 10.4 3.9 0.26 9.8 3.9 1.2 1 0 0 1 1 1 0 Yeast cortical protein KAR9 SPC25 PF06703.11 KIY67881.1 - 1.8e-52 177.4 0.0 2.2e-52 177.1 0.0 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) HEAT_2 PF13646.6 KIY67882.1 - 1.2e-10 41.7 2.3 0.08 13.3 0.0 6.3 4 1 0 4 4 4 3 HEAT repeats HEAT_EZ PF13513.6 KIY67882.1 - 1.2e-06 28.9 12.8 0.21 12.1 0.3 7.5 7 0 0 7 7 7 2 HEAT-like repeat HEAT PF02985.22 KIY67882.1 - 3.4e-06 26.8 16.1 4.9 7.7 0.0 10.1 12 0 0 12 12 12 2 HEAT repeat Adaptin_N PF01602.20 KIY67882.1 - 5.3e-06 25.3 0.2 0.0097 14.5 0.0 3.0 2 1 0 2 2 2 2 Adaptin N terminal region Cnd1 PF12717.7 KIY67882.1 - 0.00024 21.2 0.1 5.1 7.1 0.1 4.0 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 UME PF08064.13 KIY67882.1 - 0.0003 20.7 0.7 1.5 8.8 0.0 5.4 5 0 0 5 5 5 1 UME (NUC010) domain Vac14_Fab1_bd PF12755.7 KIY67882.1 - 0.0081 16.7 0.0 4.4 8.0 0.0 3.0 2 0 0 2 2 2 1 Vacuolar 14 Fab1-binding region Arm PF00514.23 KIY67882.1 - 0.025 14.6 3.3 0.039 14.0 0.1 3.2 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat V-ATPase_H_C PF11698.8 KIY67882.1 - 0.16 12.1 0.0 19 5.4 0.0 3.4 4 0 0 4 4 4 0 V-ATPase subunit H Phage_integrase PF00589.22 KIY67883.1 - 2.5e-05 24.1 0.0 5.7e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Phage integrase family GXWXG PF14231.6 KIY67887.1 - 0.11 12.6 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 GXWXG protein HOOK PF05622.12 KIY67892.1 - 0.0017 16.6 28.1 0.0017 16.6 28.1 2.0 1 1 0 2 2 2 1 HOOK protein BRE1 PF08647.11 KIY67892.1 - 0.25 11.4 35.1 0.79 9.8 16.6 3.6 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase AphA_like PF14557.6 KIY67892.1 - 0.38 10.4 5.2 0.16 11.7 1.0 2.4 2 1 1 3 3 3 0 Putative AphA-like transcriptional regulator Caveolin PF01146.17 KIY67893.1 - 7.9 6.5 9.6 12 5.8 2.1 2.3 1 1 1 2 2 2 0 Caveolin Mg_trans_NIPA PF05653.14 KIY67894.1 - 3.8e-82 275.7 32.2 5e-82 275.3 32.2 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KIY67894.1 - 1.6e-07 31.6 9.4 1.6e-07 31.6 9.4 3.5 2 2 0 3 3 3 2 EamA-like transporter family CoA_binding_2 PF13380.6 KIY67895.1 - 2.5e-33 115.0 0.0 2.8e-33 114.9 0.0 1.0 1 0 0 1 1 1 1 CoA binding domain CoA_binding PF02629.19 KIY67895.1 - 0.0093 16.6 0.0 0.012 16.3 0.0 1.2 1 0 0 1 1 1 1 CoA binding domain F-box-like PF12937.7 KIY67896.1 - 0.013 15.4 1.1 0.027 14.4 1.1 1.5 1 0 0 1 1 1 0 F-box-like COG2 PF06148.11 KIY67896.1 - 0.22 11.6 0.3 0.6 10.2 0.1 1.9 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 CDP-OH_P_transf PF01066.21 KIY67897.1 - 6e-18 65.4 0.1 6e-18 65.4 0.1 2.6 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase F-box-like PF12937.7 KIY67898.1 - 1e-10 41.4 1.2 4.8e-08 32.8 0.5 2.6 2 0 0 2 2 2 2 F-box-like F-box PF00646.33 KIY67898.1 - 0.00013 21.7 2.2 0.003 17.4 0.3 2.8 2 0 0 2 2 2 1 F-box domain Codanin-1_C PF15296.6 KIY67898.1 - 0.17 11.9 0.1 0.44 10.6 0.1 1.7 1 0 0 1 1 1 0 Codanin-1 C-terminus AFG1_ATPase PF03969.16 KIY67899.1 - 5.2e-47 160.5 0.0 2.4e-42 145.1 0.0 3.0 2 1 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.6 KIY67899.1 - 3.5e-06 27.5 0.1 1.3e-05 25.7 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KIY67899.1 - 0.0026 18.2 0.0 0.0061 17.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KIY67899.1 - 0.012 15.9 0.0 0.031 14.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KIY67899.1 - 0.022 14.5 0.0 0.049 13.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.6 KIY67899.1 - 0.024 14.8 0.0 0.055 13.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KIY67899.1 - 0.032 14.6 0.2 0.35 11.2 0.2 2.2 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KIY67899.1 - 0.06 12.9 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KIY67899.1 - 0.066 12.9 0.0 2.6 7.7 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF2075 PF09848.9 KIY67899.1 - 0.13 11.5 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.12 KIY67899.1 - 0.14 11.4 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_11 PF13086.6 KIY67899.1 - 0.2 11.4 0.0 0.31 10.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KIY67899.1 - 0.21 12.0 0.0 0.4 11.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase SCP-1 PF05483.12 KIY67900.1 - 5.6e-05 21.4 3.3 6.3e-05 21.2 3.3 1.0 1 0 0 1 1 1 1 Synaptonemal complex protein 1 (SCP-1) DUF812 PF05667.11 KIY67900.1 - 0.00025 20.1 6.7 0.00028 19.9 6.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF812) JIP_LZII PF16471.5 KIY67900.1 - 0.008 16.3 1.9 0.012 15.7 1.6 1.5 1 1 0 1 1 1 1 JNK-interacting protein leucine zipper II DUF3288 PF11691.8 KIY67900.1 - 0.03 14.4 0.4 0.062 13.4 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3288) DivIC PF04977.15 KIY67900.1 - 0.052 13.3 1.6 0.052 13.3 1.6 2.1 1 1 1 2 2 2 0 Septum formation initiator DUF5496 PF17600.2 KIY67900.1 - 0.057 13.5 0.0 0.092 12.8 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5496) APC_N_CC PF16689.5 KIY67900.1 - 0.083 13.0 0.8 1.1 9.3 0.5 2.6 2 1 0 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain ADIP PF11559.8 KIY67900.1 - 0.093 12.8 5.0 0.12 12.5 5.0 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF2570 PF10828.8 KIY67900.1 - 0.098 12.5 4.1 0.15 11.8 1.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) Hemagglutinin PF00509.18 KIY67900.1 - 0.15 10.5 1.2 0.16 10.3 1.2 1.0 1 0 0 1 1 1 0 Haemagglutinin APG6_N PF17675.1 KIY67900.1 - 0.3 11.6 9.0 0.52 10.8 9.0 1.5 1 1 0 1 1 1 0 Apg6 coiled-coil region F-box-like PF12937.7 KIY67901.1 - 1.7e-09 37.4 4.7 1.2e-08 34.7 0.4 3.7 5 0 0 5 5 5 1 F-box-like F-box PF00646.33 KIY67901.1 - 0.00059 19.6 5.0 0.0012 18.6 0.2 3.2 3 0 0 3 3 3 1 F-box domain BACK PF07707.15 KIY67901.1 - 0.011 15.9 0.0 0.024 14.8 0.0 1.5 1 0 0 1 1 1 0 BTB And C-terminal Kelch F-box-like PF12937.7 KIY67902.1 - 0.0011 18.8 0.5 0.0031 17.4 0.1 2.0 2 0 0 2 2 2 1 F-box-like bZIP_1 PF00170.21 KIY67903.1 - 2.9e-10 40.1 11.0 4.6e-09 36.2 6.8 2.2 2 0 0 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.15 KIY67903.1 - 5.8e-09 35.9 16.2 3.9e-08 33.2 8.4 2.3 2 0 0 2 2 2 2 Basic region leucine zipper bZIP_Maf PF03131.17 KIY67903.1 - 0.03 14.8 4.9 0.03 14.8 4.9 1.8 2 0 0 2 2 2 0 bZIP Maf transcription factor HALZ PF02183.18 KIY67903.1 - 0.088 13.0 1.1 0.68 10.2 0.0 2.2 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF724 PF05266.14 KIY67903.1 - 0.16 11.8 0.4 0.23 11.3 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) HAP1_N PF04849.13 KIY67903.1 - 0.34 10.1 2.2 0.3 10.3 0.7 1.5 1 1 0 1 1 1 0 HAP1 N-terminal conserved region DUF5384 PF17358.2 KIY67903.1 - 1.4 9.0 12.8 0.035 14.2 6.5 1.4 2 0 0 2 2 2 0 Family of unknown function (DUF5384) Methyltransf_22 PF13383.6 KIY67904.1 - 0.00039 20.1 0.2 0.0006 19.5 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase domain F-box-like PF12937.7 KIY67905.1 - 1.4e-05 24.9 1.1 4.2e-05 23.3 1.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY67905.1 - 0.37 10.7 3.7 12 5.9 1.8 2.5 2 0 0 2 2 2 0 F-box domain TMF_DNA_bd PF12329.8 KIY67906.1 - 4.3e-05 23.4 20.0 0.0033 17.4 11.8 2.6 2 0 0 2 2 2 2 TATA element modulatory factor 1 DNA binding DUF4201 PF13870.6 KIY67906.1 - 0.0087 15.8 8.1 0.0087 15.8 8.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) HALZ PF02183.18 KIY67906.1 - 0.022 15.0 8.1 0.7 10.2 2.1 2.6 1 1 1 2 2 2 0 Homeobox associated leucine zipper ZapB PF06005.12 KIY67906.1 - 0.026 14.9 10.6 0.026 14.9 10.6 2.6 2 2 0 2 2 2 0 Cell division protein ZapB DUF5344 PF17279.2 KIY67906.1 - 0.14 12.7 2.6 0.99 10.0 0.1 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5344) CENP-F_leu_zip PF10473.9 KIY67906.1 - 0.16 12.0 14.6 0.046 13.8 9.5 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 JIP_LZII PF16471.5 KIY67906.1 - 0.26 11.5 10.1 0.59 10.3 10.1 1.6 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II YabA PF06156.13 KIY67906.1 - 0.9 10.2 10.3 9.9 6.9 8.5 2.7 1 1 2 3 3 3 0 Initiation control protein YabA CALCOCO1 PF07888.11 KIY67906.1 - 0.91 8.3 23.0 1.3 7.8 23.0 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like ADIP PF11559.8 KIY67906.1 - 0.93 9.6 22.3 0.1 12.7 12.8 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF3450 PF11932.8 KIY67906.1 - 1 8.6 15.8 0.76 9.0 5.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Syntaxin-6_N PF09177.11 KIY67906.1 - 1.4 9.6 11.1 19 5.9 0.2 2.8 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Spc7 PF08317.11 KIY67906.1 - 1.6 7.5 21.7 1.1 8.0 16.3 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein DivIC PF04977.15 KIY67906.1 - 1.7 8.4 24.8 0.31 10.8 4.6 4.3 2 2 2 4 4 4 0 Septum formation initiator KxDL PF10241.9 KIY67906.1 - 2.2 8.6 9.5 1.1 9.6 5.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein KASH_CCD PF14662.6 KIY67906.1 - 2.9 7.7 20.6 0.89 9.4 15.5 2.2 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH Tropomyosin_1 PF12718.7 KIY67906.1 - 3.6 7.7 23.2 0.69 10.1 2.5 2.3 2 0 0 2 2 2 0 Tropomyosin like bZIP_1 PF00170.21 KIY67906.1 - 3.9 7.6 15.2 1.2 9.2 2.5 3.0 2 1 1 3 3 3 0 bZIP transcription factor TPR_MLP1_2 PF07926.12 KIY67906.1 - 4.2 7.5 21.6 12 6.0 10.5 2.7 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein APG6_N PF17675.1 KIY67906.1 - 5.3 7.6 26.5 0.24 11.9 15.3 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region CENP-H PF05837.12 KIY67906.1 - 5.9 7.3 16.7 0.39 11.2 7.8 2.3 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Fib_alpha PF08702.10 KIY67906.1 - 9.1 6.5 9.2 8.7 6.5 4.6 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Mito_carr PF00153.27 KIY67907.1 - 3.3e-62 206.5 4.7 1e-20 73.4 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein zf-C2H2 PF00096.26 KIY67908.1 - 6.2e-14 51.6 14.0 0.00016 21.9 1.4 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KIY67908.1 - 4.9e-09 36.2 7.1 6.3e-06 26.4 0.1 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KIY67908.1 - 3e-08 33.8 11.6 0.006 17.3 0.8 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KIY67908.1 - 0.0044 17.3 4.0 5.6 7.4 0.0 3.3 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding C1_4 PF07975.12 KIY67908.1 - 0.0064 16.7 3.5 0.012 15.8 2.8 1.8 1 1 1 2 2 2 1 TFIIH C1-like domain zf-C2H2_8 PF15909.5 KIY67908.1 - 0.015 15.6 2.7 0.021 15.1 0.8 2.0 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-met PF12874.7 KIY67908.1 - 0.029 14.8 5.8 3.1 8.3 0.1 3.8 4 0 0 4 4 4 0 Zinc-finger of C2H2 type Zn_ribbon_SprT PF17283.2 KIY67908.1 - 0.15 12.0 4.8 4 7.4 0.1 2.3 2 0 0 2 2 2 0 SprT-like zinc ribbon domain Sigma70_ner PF04546.13 KIY67908.1 - 0.31 10.9 9.0 1.4 8.8 0.8 2.4 2 0 0 2 2 2 0 Sigma-70, non-essential region zf-C2H2_6 PF13912.6 KIY67908.1 - 0.5 10.4 8.2 15 5.8 0.3 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger Mut7-C PF01927.16 KIY67908.1 - 1.4 9.0 3.5 2.7 8.1 1.5 2.4 3 0 0 3 3 3 0 Mut7-C RNAse domain CENP-B_dimeris PF09026.10 KIY67908.1 - 4 7.9 15.4 1.6 9.1 1.0 3.1 3 0 0 3 3 3 0 Centromere protein B dimerisation domain Glyco_hydro_18 PF00704.28 KIY67910.1 - 2.5e-58 198.3 0.1 3e-58 198.0 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_114 PF03537.13 KIY67910.1 - 0.048 13.0 0.0 0.079 12.3 0.0 1.3 1 0 0 1 1 1 0 Glycoside-hydrolase family GH114 DUF4849 PF16141.5 KIY67910.1 - 0.24 10.6 0.0 0.91 8.7 0.0 1.7 1 1 1 2 2 2 0 Putative glycoside hydrolase Family 18, chitinase_18 Pkinase PF00069.25 KIY67911.1 - 1.6e-69 234.2 0.0 2.1e-69 233.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY67911.1 - 2.6e-36 125.2 0.0 3.4e-36 124.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 KIY67911.1 - 1.3e-18 67.1 0.7 2.4e-18 66.3 0.3 1.7 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 KIY67911.1 - 1.6e-05 25.1 0.0 3.5e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Kinase-like PF14531.6 KIY67911.1 - 2e-05 24.1 0.0 6.9e-05 22.3 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KIY67911.1 - 0.0019 17.6 0.1 0.0043 16.4 0.1 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KIY67911.1 - 0.0028 16.6 0.1 0.0041 16.1 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KIY67911.1 - 0.0061 16.5 0.0 0.016 15.1 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KIY67911.1 - 0.11 11.3 0.0 0.2 10.4 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase DUF3516 PF12029.8 KIY67911.1 - 0.16 11.0 0.1 0.23 10.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3516) Fungal_trans PF04082.18 KIY67912.1 - 8.6e-15 54.5 0.0 1.3e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain F-box PF00646.33 KIY67914.1 - 0.0021 17.9 0.2 0.02 14.8 0.1 2.6 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KIY67914.1 - 0.045 13.7 1.0 0.12 12.3 0.5 2.1 2 0 0 2 2 2 0 F-box-like Gti1_Pac2 PF09729.9 KIY67915.1 - 3e-21 76.3 6.4 7.4e-19 68.5 0.0 3.0 2 2 1 3 3 3 2 Gti1/Pac2 family DUF836 PF05768.14 KIY67916.1 - 0.051 14.0 0.0 0.099 13.1 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) GST_N_3 PF13417.6 KIY67916.1 - 0.13 12.7 0.0 0.52 10.8 0.0 2.0 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Prok-RING_1 PF14446.6 KIY67918.1 - 1.7 8.6 6.2 4.4 7.3 6.2 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-AN1 PF01428.16 KIY67918.1 - 9.1 6.5 7.1 0.43 10.8 1.4 1.7 2 0 0 2 2 2 0 AN1-like Zinc finger adh_short PF00106.25 KIY67920.1 - 5.9e-32 110.7 0.0 4.4e-27 94.8 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KIY67920.1 - 9.5e-22 77.7 0.0 1.2e-19 70.8 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIY67920.1 - 5.5e-06 26.4 0.0 8.7e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KIY67920.1 - 0.0065 16.0 0.0 0.0084 15.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family SMC_hinge PF06470.13 KIY67920.1 - 0.0079 16.5 0.0 0.015 15.6 0.0 1.4 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain CRISPR_Cas2 PF09827.9 KIY67920.1 - 0.18 12.0 0.0 0.39 10.9 0.0 1.5 1 0 0 1 1 1 0 CRISPR associated protein Cas2 PX PF00787.24 KIY67921.1 - 1.1e-11 44.7 0.0 1.7e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 PX domain peroxidase PF00141.23 KIY67923.1 - 2.8e-47 161.4 0.0 4.4e-47 160.7 0.0 1.3 1 0 0 1 1 1 1 Peroxidase CAP59_mtransfer PF11735.8 KIY67924.1 - 1.8e-66 224.3 0.0 2.4e-66 223.9 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 FixQ PF05545.11 KIY67924.1 - 0.18 11.8 0.1 0.18 11.8 0.1 1.9 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ TBK1_ULD PF18396.1 KIY67928.1 - 0.025 14.5 0.0 0.099 12.6 0.0 1.9 1 1 1 2 2 2 0 TANK binding kinase 1 ubiquitin-like domain Pkinase PF00069.25 KIY67931.1 - 1.8e-60 204.6 0.0 8.3e-40 136.8 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIY67931.1 - 2.7e-27 95.7 0.0 3e-22 79.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.24 KIY67931.1 - 5.4e-12 45.9 0.0 1.2e-11 44.8 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.6 KIY67931.1 - 2.8e-07 30.2 0.0 0.00093 18.6 0.0 2.3 2 0 0 2 2 2 2 Kinase-like PAS_9 PF13426.7 KIY67931.1 - 7.3e-05 23.0 0.0 0.00021 21.5 0.0 1.7 1 0 0 1 1 1 1 PAS domain APH PF01636.23 KIY67931.1 - 0.0017 18.3 0.0 0.0041 17.1 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KIY67931.1 - 0.0046 16.4 0.0 0.0082 15.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KIY67931.1 - 0.0055 16.3 0.0 4.1 7.0 0.0 2.4 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 PAS_4 PF08448.10 KIY67931.1 - 0.0063 16.7 0.1 0.018 15.3 0.1 1.8 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 KIY67931.1 - 0.0097 15.9 0.1 0.022 14.8 0.1 1.6 1 0 0 1 1 1 1 PAS fold Haspin_kinase PF12330.8 KIY67931.1 - 0.011 14.7 0.9 0.021 13.8 0.0 1.8 2 0 0 2 2 2 0 Haspin like kinase domain RIO1 PF01163.22 KIY67931.1 - 0.11 12.1 0.0 0.26 10.9 0.0 1.6 1 0 0 1 1 1 0 RIO1 family PAS_11 PF14598.6 KIY67931.1 - 0.17 12.0 0.0 0.34 11.0 0.0 1.5 1 0 0 1 1 1 0 PAS domain DUF2007 PF09413.10 KIY67931.1 - 0.18 12.0 0.0 0.38 11.0 0.0 1.5 1 0 0 1 1 1 0 Putative prokaryotic signal transducing protein Seadorna_VP7 PF07387.11 KIY67931.1 - 0.19 10.8 0.0 0.33 10.0 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 zinc-ribbons_6 PF07191.12 KIY67931.1 - 0.59 10.2 1.8 1.1 9.3 1.8 1.4 1 0 0 1 1 1 0 zinc-ribbons Ribosomal_S18 PF01084.20 KIY67932.1 - 7.1e-14 51.8 0.1 2.4e-13 50.1 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein S18 JAB PF01398.21 KIY67933.1 - 1.1e-32 112.4 0.2 1.9e-32 111.7 0.2 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 KIY67933.1 - 8.9e-15 55.1 0.9 1.6e-14 54.3 0.9 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 KIY67933.1 - 2e-06 27.6 0.0 3.5e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain DUF5624 PF18538.1 KIY67933.1 - 0.097 12.8 0.1 0.18 11.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5624) CTD_bind PF04818.13 KIY67934.1 - 0.00069 20.4 0.0 0.0018 19.1 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase II-binding domain. Zn-C2H2_12 PF18112.1 KIY67934.1 - 0.068 13.7 2.8 3.8 8.1 0.1 2.8 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_4 PF13894.6 KIY67934.1 - 0.19 12.7 5.1 2.4 9.2 0.2 3.7 4 0 0 4 4 4 0 C2H2-type zinc finger Ribosomal_L6 PF00347.23 KIY67935.1 - 7.9e-25 87.3 3.9 1.9e-14 54.1 1.8 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Flavi_capsid PF01003.19 KIY67935.1 - 0.041 13.6 0.2 0.069 12.9 0.2 1.3 1 0 0 1 1 1 0 Flavivirus capsid protein C HAD_2 PF13419.6 KIY67936.1 - 5.5e-08 33.1 0.0 2e-07 31.3 0.0 1.8 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KIY67936.1 - 4.3e-07 30.4 0.0 4.3e-06 27.2 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KIY67936.1 - 0.00042 20.3 0.0 0.0008 19.4 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Acid_PPase PF12689.7 KIY67936.1 - 0.0062 16.4 0.0 0.033 14.0 0.0 1.9 2 0 0 2 2 2 1 Acid Phosphatase DUF2608 PF11019.8 KIY67936.1 - 0.0072 15.8 0.0 1.3 8.4 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2608) UPF0183 PF03676.14 KIY67937.1 - 8.3e-60 203.1 0.0 1.3e-59 202.4 0.0 1.3 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0183) DNA_pol_E_B PF04042.16 KIY67938.1 - 4.9e-44 150.2 0.6 8e-44 149.5 0.6 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 KIY67938.1 - 0.008 16.3 0.1 0.015 15.4 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain Apt1 PF10351.9 KIY67939.1 - 3e-69 234.1 0.0 3e-69 234.1 0.0 2.1 2 0 0 2 2 2 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.9 KIY67939.1 - 1.1e-53 182.8 0.0 1.7e-28 99.8 0.1 2.2 1 1 1 2 2 2 2 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.9 KIY67939.1 - 5.3e-32 111.1 0.0 1.1e-31 110.1 0.0 1.6 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 KIY67939.1 - 2.3e-27 95.8 0.0 6.5e-27 94.4 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.9 KIY67939.1 - 2.6e-11 44.1 0.0 7.2e-11 42.7 0.0 1.8 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2985 PF11204.8 KIY67942.1 - 8.4e-28 96.3 1.5 1.5e-27 95.5 1.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) TruD PF01142.18 KIY67943.1 - 4.1e-74 249.9 0.2 4.5e-71 239.9 0.1 3.0 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) FoP_duplication PF13865.6 KIY67943.1 - 5.1 7.7 32.7 4 8.0 18.2 3.4 3 0 0 3 3 3 0 C-terminal duplication domain of Friend of PRMT1 MFS_1 PF07690.16 KIY67944.1 - 9.8e-32 110.2 24.0 1.6e-30 106.2 14.5 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIY67944.1 - 2.2e-06 26.8 1.9 2.2e-06 26.8 1.9 2.4 1 1 1 2 2 2 1 Sugar (and other) transporter MFS_5 PF05631.14 KIY67944.1 - 0.00031 19.8 0.7 0.0019 17.2 0.1 2.1 2 0 0 2 2 2 1 Sugar-tranasporters, 12 TM PIN_4 PF13638.6 KIY67945.1 - 7.6e-23 81.2 0.2 1.5e-22 80.3 0.2 1.5 1 0 0 1 1 1 1 PIN domain Gly_transf_sug PF04488.15 KIY67946.1 - 3e-21 75.9 0.0 6e-21 74.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 KIY67946.1 - 0.25 10.6 0.3 0.43 9.8 0.3 1.3 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain DegT_DnrJ_EryC1 PF01041.17 KIY67947.1 - 0.0071 15.7 0.0 0.0087 15.4 0.0 1.0 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family DUF2721 PF11026.8 KIY67947.1 - 0.033 14.1 0.2 0.045 13.7 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) Snapin_Pallidin PF14712.6 KIY67947.1 - 0.036 14.5 1.1 0.051 14.0 1.1 1.3 1 0 0 1 1 1 0 Snapin/Pallidin Pox_C4_C10 PF03336.13 KIY67947.1 - 0.082 12.0 0.1 0.1 11.7 0.1 1.1 1 0 0 1 1 1 0 Poxvirus C4/C10 protein DUF3629 PF12302.8 KIY67947.1 - 0.13 11.7 0.9 0.15 11.5 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3629) RhoGEF PF00621.20 KIY67948.1 - 5.6e-33 114.7 0.2 1.2e-32 113.6 0.2 1.6 1 0 0 1 1 1 1 RhoGEF domain DUF3496 PF12001.8 KIY67948.1 - 0.064 13.6 0.2 0.064 13.6 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3496) DUF5553 PF17707.1 KIY67949.1 - 0.16 11.4 0.1 0.23 10.9 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5553) PPI_Ypi1 PF07491.11 KIY67950.1 - 3.2e-25 87.7 1.0 6.3e-25 86.8 1.0 1.4 1 0 0 1 1 1 1 Protein phosphatase inhibitor Ferric_reduct PF01794.19 KIY67951.1 - 1.9e-19 70.0 3.4 1.9e-19 70.0 3.4 1.8 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KIY67951.1 - 3.1e-11 43.3 0.0 5.5e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 KIY67951.1 - 4.4e-08 33.4 0.0 0.00063 19.9 0.0 2.3 1 1 1 2 2 2 2 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 KIY67951.1 - 0.12 13.1 0.0 27 5.4 0.0 2.6 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain THOC7 PF05615.13 KIY67953.1 - 2.2e-27 95.9 5.7 2.2e-27 95.9 5.7 1.8 1 1 1 2 2 2 1 Tho complex subunit 7 HCMV_UL139 PF12507.8 KIY67953.1 - 0.087 13.2 2.2 12 6.3 0.2 2.4 1 1 0 2 2 2 0 Human Cytomegalovirus UL139 protein zf-C4H2 PF10146.9 KIY67953.1 - 0.1 12.9 4.9 0.12 12.6 4.9 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein DUF1664 PF07889.12 KIY67953.1 - 0.23 11.5 5.6 0.22 11.6 1.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) TMPIT PF07851.13 KIY67953.1 - 0.34 10.1 3.8 0.48 9.6 3.8 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF724 PF05266.14 KIY67953.1 - 1.4 8.7 5.1 2.9 7.7 4.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF724) DUF4200 PF13863.6 KIY67953.1 - 1.5 9.2 10.6 2.4 8.6 3.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) FUSC PF04632.12 KIY67953.1 - 2.1 6.8 3.9 2.6 6.5 3.9 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family V_ATPase_I PF01496.19 KIY67953.1 - 3.9 5.3 5.3 5.1 4.9 5.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc7 PF08317.11 KIY67953.1 - 4.4 6.1 12.5 3.8 6.3 9.8 1.9 1 1 0 1 1 1 0 Spc7 kinetochore protein Lactamase_B_2 PF12706.7 KIY67954.1 - 9.3e-14 51.4 0.1 2.4e-08 33.8 0.0 2.4 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.6 KIY67954.1 - 8.2e-06 25.4 0.0 1.5e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B PF00753.27 KIY67954.1 - 1.3e-05 25.3 0.6 3.6e-05 23.9 0.4 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily MutS_V PF00488.21 KIY67955.1 - 2.9e-83 278.6 0.1 4.7e-83 277.8 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KIY67955.1 - 7.6e-36 124.1 0.8 1.8e-35 122.9 0.8 1.6 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 KIY67955.1 - 8e-15 55.0 0.7 8e-15 55.0 0.7 2.2 2 0 0 2 2 2 1 MutS family domain IV MutS_II PF05188.17 KIY67955.1 - 3.7e-13 49.9 0.0 2e-12 47.6 0.0 2.2 3 0 0 3 3 3 1 MutS domain II MutS_I PF01624.20 KIY67955.1 - 6.2e-07 29.7 0.0 1.7e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 MutS domain I FTA4 PF13093.6 KIY67955.1 - 0.075 12.9 0.3 0.92 9.4 0.1 2.7 1 1 1 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 AAA_27 PF13514.6 KIY67955.1 - 0.087 12.4 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain LOH1CR12 PF10158.9 KIY67955.1 - 0.19 11.8 2.3 3.1 7.8 0.1 3.6 4 0 0 4 4 4 0 Tumour suppressor protein AAA_23 PF13476.6 KIY67955.1 - 0.25 11.8 3.1 8.3 6.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain Amidohydro_1 PF01979.20 KIY67956.1 - 9.3e-10 38.3 0.0 3.2e-09 36.6 0.0 1.8 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_3 PF07969.11 KIY67956.1 - 2.3e-09 37.3 1.9 1.6e-08 34.5 0.1 2.7 3 0 0 3 3 3 1 Amidohydrolase family RhoGEF PF00621.20 KIY67957.1 - 8e-17 62.1 0.0 5.4e-16 59.4 0.0 2.2 1 1 0 1 1 1 1 RhoGEF domain PH PF00169.29 KIY67957.1 - 0.14 12.7 0.0 0.32 11.5 0.0 1.6 1 0 0 1 1 1 0 PH domain DUF5310 PF17237.2 KIY67958.1 - 3.5e-16 58.8 4.1 5.4e-16 58.2 4.1 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5310) LRR_6 PF13516.6 KIY67959.1 - 1.6e-13 49.5 8.2 0.086 12.9 0.0 8.1 7 0 0 7 7 7 5 Leucine Rich repeat LRR_4 PF12799.7 KIY67959.1 - 8.6e-10 38.7 8.6 0.036 14.5 0.0 7.1 6 1 3 9 9 9 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KIY67959.1 - 0.00024 21.2 11.9 15 6.6 0.0 7.5 7 1 0 7 7 7 2 Leucine Rich Repeat LRR_8 PF13855.6 KIY67959.1 - 1 9.2 10.8 1.4 8.7 0.0 5.1 5 2 1 6 6 6 0 Leucine rich repeat Myb_DNA-binding PF00249.31 KIY67960.1 - 4.2e-24 84.5 6.8 6.1e-12 45.5 0.7 3.8 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KIY67960.1 - 3.2e-20 72.1 0.0 1.1e-12 47.9 0.2 3.7 2 1 1 3 3 3 2 Myb-like DNA-binding domain Rap1_C PF11626.8 KIY67960.1 - 0.034 14.2 0.0 0.13 12.4 0.0 2.0 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain MADF_DNA_bdg PF10545.9 KIY67960.1 - 0.21 12.0 5.1 3.6 8.0 0.1 3.8 3 1 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF2052 PF09747.9 KIY67961.1 - 1.3e-06 28.7 19.7 1.5e-05 25.3 19.7 2.1 1 1 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) Acetyltransf_7 PF13508.7 KIY67963.1 - 3.1e-09 37.1 0.0 7.2e-09 36.0 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIY67963.1 - 5e-08 33.2 0.0 7.4e-08 32.6 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KIY67963.1 - 2e-07 31.0 0.0 3.4e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIY67963.1 - 5.5e-07 29.5 0.0 1.1e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 KIY67963.1 - 0.0057 17.3 0.6 0.061 14.0 0.6 2.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain MOZ_SAS PF01853.18 KIY67963.1 - 0.029 14.0 0.0 0.053 13.2 0.0 1.4 1 0 0 1 1 1 0 MOZ/SAS family Acetyltransf_CG PF14542.6 KIY67963.1 - 0.056 13.6 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DUF2370 PF10176.9 KIY67964.1 - 5.5e-75 251.9 0.0 9.1e-75 251.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) Sigma70_r4_2 PF08281.12 KIY67964.1 - 0.064 12.9 0.1 0.13 11.9 0.1 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 DUF4064 PF13273.6 KIY67964.1 - 0.2 11.9 1.3 0.57 10.5 1.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) OMPdecase PF00215.24 KIY67966.1 - 2.6e-70 236.5 0.1 3.2e-70 236.2 0.1 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family LDcluster4 PF18306.1 KIY67966.1 - 0.016 14.8 1.1 0.026 14.1 1.1 1.2 1 0 0 1 1 1 0 SLOG cluster4 family HD PF01966.22 KIY67967.1 - 2.2e-14 53.7 0.6 5.3e-14 52.5 0.2 1.9 2 0 0 2 2 2 1 HD domain PDEase_I PF00233.19 KIY67967.1 - 0.025 14.3 0.1 0.045 13.5 0.1 1.4 1 0 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase HDOD PF08668.12 KIY67967.1 - 0.12 11.9 0.0 0.77 9.2 0.0 2.1 2 0 0 2 2 2 0 HDOD domain Pkinase PF00069.25 KIY67968.1 - 2.2e-62 210.8 0.1 3e-62 210.4 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY67968.1 - 6e-36 124.1 0.1 7.9e-36 123.7 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY67968.1 - 3.2e-08 33.2 0.0 5.7e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KIY67968.1 - 0.00022 20.2 0.0 0.00035 19.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KIY67968.1 - 0.013 15.4 0.1 0.022 14.7 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 KIY67968.1 - 0.013 14.8 0.2 0.15 11.4 0.1 2.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KIY67968.1 - 0.03 13.3 0.2 0.041 12.8 0.2 1.2 1 0 0 1 1 1 0 Haspin like kinase domain p450 PF00067.22 KIY67969.1 - 9e-73 245.6 0.0 1.1e-72 245.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Not1 PF04054.15 KIY67972.1 - 1.1e-127 426.0 0.3 3e-127 424.5 0.3 1.9 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 KIY67972.1 - 2.6e-86 288.6 0.2 1.1e-84 283.4 0.0 2.6 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain DUF3819 PF12842.7 KIY67972.1 - 4.6e-53 179.1 0.2 1.2e-52 177.7 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) CNOT1_TTP_bind PF16417.5 KIY67972.1 - 6.1e-53 178.8 0.0 1.3e-52 177.8 0.0 1.5 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain CNOT1_HEAT PF16418.5 KIY67972.1 - 5.1e-46 156.5 0.2 1.3e-45 155.1 0.2 1.7 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 HEAT repeat FdhE PF04216.12 KIY67972.1 - 0.16 11.8 0.1 0.53 10.1 0.1 2.0 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation CDC50 PF03381.15 KIY67973.1 - 9.4e-94 314.0 0.5 1.2e-93 313.7 0.5 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family MCM_bind PF09739.9 KIY67975.1 - 6.9e-71 239.4 0.0 3.4e-62 210.7 0.0 3.0 1 1 0 2 2 2 2 Mini-chromosome maintenance replisome factor MCM_lid PF17855.1 KIY67975.1 - 0.0024 18.2 0.1 0.0043 17.4 0.1 1.4 1 0 0 1 1 1 1 MCM AAA-lid domain FMO-like PF00743.19 KIY67976.1 - 3.6e-12 45.5 0.0 1.1e-05 24.1 0.0 3.1 3 1 0 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KIY67976.1 - 1.9e-08 33.9 0.0 0.0058 15.9 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KIY67976.1 - 2.1e-08 33.8 0.0 0.02 14.2 0.1 3.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIY67976.1 - 2.5e-08 34.0 0.0 1e-07 32.1 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KIY67976.1 - 2.4e-05 23.7 0.6 0.18 10.9 0.0 3.2 4 0 0 4 4 4 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KIY67976.1 - 0.00011 22.3 1.3 0.0019 18.2 0.0 3.1 4 0 0 4 4 4 1 FAD-NAD(P)-binding DAO PF01266.24 KIY67976.1 - 0.00018 21.2 1.8 0.0024 17.5 0.1 2.7 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KIY67976.1 - 0.00073 20.0 0.0 0.052 14.1 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 KIY67976.1 - 0.0014 18.5 0.0 0.0032 17.4 0.0 1.6 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.17 KIY67976.1 - 0.0051 16.1 0.0 0.22 10.8 0.0 2.2 2 0 0 2 2 2 1 Thi4 family NAD_binding_2 PF03446.15 KIY67976.1 - 0.014 15.6 0.0 0.047 13.9 0.0 1.8 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase HI0933_like PF03486.14 KIY67976.1 - 0.014 14.2 0.0 0.027 13.2 0.0 1.5 2 0 0 2 2 2 0 HI0933-like protein 2-Hacid_dh_C PF02826.19 KIY67976.1 - 0.084 12.2 0.0 6.9 6.0 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 KIY67976.1 - 0.1 12.6 0.0 0.28 11.2 0.0 1.7 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.20 KIY67976.1 - 0.13 12.4 0.0 5.1 7.2 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 KIY67976.1 - 0.14 11.2 0.0 0.39 9.7 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain AlaDh_PNT_C PF01262.21 KIY67976.1 - 0.15 11.3 0.1 0.34 10.2 0.0 1.5 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain F-box-like PF12937.7 KIY67978.1 - 2.1e-06 27.5 1.4 5.5e-06 26.2 1.4 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY67978.1 - 0.23 11.4 1.4 30 4.6 0.0 2.6 2 0 0 2 2 2 0 F-box domain Hist_deacetyl PF00850.19 KIY67979.1 - 4.1e-80 269.5 0.0 4.9e-80 269.3 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain GST_N_3 PF13417.6 KIY67980.1 - 4.3e-11 43.1 0.0 7.4e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KIY67980.1 - 2.7e-10 40.4 0.1 6.8e-10 39.1 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Tom37 PF10568.9 KIY67980.1 - 0.015 15.6 0.0 0.024 14.9 0.0 1.3 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein GST_C PF00043.25 KIY67980.1 - 0.026 14.7 0.0 0.044 14.0 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KIY67980.1 - 0.041 13.9 0.1 0.14 12.2 0.1 2.0 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KIY67980.1 - 0.066 13.4 0.0 0.19 11.9 0.0 1.8 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KIY67981.1 - 6.4e-10 39.3 0.0 1.3e-09 38.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KIY67981.1 - 2.2e-08 34.3 0.0 4.1e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KIY67981.1 - 0.0025 18.0 0.0 0.0053 17.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KIY67981.1 - 0.007 16.4 0.1 0.017 15.1 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KIY67982.1 - 1.8e-08 34.7 0.1 5e-08 33.2 0.1 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KIY67982.1 - 4.3e-08 33.3 0.0 9.5e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Tom37 PF10568.9 KIY67982.1 - 0.02 15.2 0.0 0.04 14.2 0.0 1.5 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.6 KIY67982.1 - 0.021 14.8 0.1 0.043 13.8 0.1 1.7 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain CRAL_TRIO PF00650.20 KIY67983.1 - 6.1e-33 113.8 0.0 9.6e-33 113.2 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KIY67983.1 - 2.3e-10 40.5 1.5 5.8e-10 39.2 1.5 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain EMG1 PF03587.14 KIY67984.1 - 1.9e-76 256.1 0.0 2.2e-76 255.8 0.0 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase DUF1348 PF07080.11 KIY67985.1 - 7.8e-62 207.0 2.3 8.9e-62 206.8 2.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) DUF4440 PF14534.6 KIY67985.1 - 1.4e-05 25.4 0.0 1.8e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_2 PF12680.7 KIY67985.1 - 2.6e-05 24.8 0.3 3.5e-05 24.4 0.3 1.2 1 0 0 1 1 1 1 SnoaL-like domain GST_N_3 PF13417.6 KIY67986.1 - 4e-08 33.6 0.0 7.8e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KIY67986.1 - 3.5e-06 27.2 0.0 6.4e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 KIY67986.1 - 0.014 16.1 0.0 0.065 14.0 0.0 1.9 1 1 1 2 2 2 0 Glutathione S-transferase N-terminal domain Tom37 PF10568.9 KIY67986.1 - 0.03 14.6 0.0 0.048 14.0 0.0 1.3 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein DUF1828 PF08861.10 KIY67987.1 - 0.042 14.1 1.3 0.24 11.7 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF1828 Csm1_N PF18504.1 KIY67987.1 - 0.27 11.6 16.0 0.32 11.4 2.7 3.2 2 1 1 3 3 3 0 Csm1 N-terminal domain RTC PF01137.21 KIY67988.1 - 2.3e-84 282.0 0.1 2.6e-84 281.8 0.1 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 KIY67988.1 - 3.3e-23 82.2 1.5 5.5e-23 81.4 1.5 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain Peptidase_M43 PF05572.13 KIY67989.1 - 3e-07 30.5 0.0 1e-06 28.7 0.0 1.8 2 0 0 2 2 2 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 KIY67989.1 - 0.0029 17.8 0.1 0.0054 16.9 0.1 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M43 PF05572.13 KIY67990.1 - 2e-11 44.0 0.1 5.1e-11 42.7 0.1 1.6 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_4 PF13583.6 KIY67990.1 - 0.0063 16.2 0.1 0.018 14.7 0.1 1.8 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KIY67990.1 - 0.013 15.6 0.8 0.032 14.4 0.5 1.6 1 1 0 1 1 1 0 Metallo-peptidase family M12 Peptidase_M66 PF10462.9 KIY67990.1 - 0.022 13.7 1.0 0.036 13.0 1.0 1.2 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M10 PF00413.24 KIY67990.1 - 0.031 14.1 0.0 0.052 13.4 0.0 1.4 1 1 0 1 1 1 0 Matrixin Reprolysin_3 PF13582.6 KIY67990.1 - 0.053 14.0 0.4 0.12 12.9 0.4 1.8 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Tim17 PF02466.19 KIY67991.1 - 1.4e-22 80.2 8.3 2.2e-22 79.5 8.3 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family F-box-like PF12937.7 KIY67992.1 - 2.4e-08 33.8 0.2 7.7e-08 32.1 0.2 2.0 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KIY67994.1 - 2.2e-08 33.8 0.2 4.7e-08 32.8 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY67994.1 - 0.041 13.8 0.3 0.37 10.7 0.3 2.6 1 1 0 1 1 1 0 F-box domain F-box-like_2 PF13013.6 KIY67994.1 - 0.068 13.1 0.1 0.27 11.2 0.0 1.9 2 0 0 2 2 2 0 F-box-like domain LRR_4 PF12799.7 KIY67994.1 - 0.087 13.3 0.3 36 5.0 0.0 3.4 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) MHB PF16525.5 KIY67994.1 - 0.092 13.0 0.0 0.25 11.6 0.0 1.7 1 0 0 1 1 1 0 Haemophore, haem-binding AcetylCoA_hydro PF02550.15 KIY67997.1 - 2e-48 165.0 0.0 3.2e-48 164.4 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.6 KIY67997.1 - 3.3e-41 140.8 0.0 5.2e-41 140.1 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain DUF4010 PF13194.6 KIY67998.1 - 0.19 11.4 9.5 0.85 9.3 9.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4010) DUF2839 PF10999.8 KIY67998.1 - 0.97 9.8 4.6 0.3 11.5 0.5 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2839) F-box-like PF12937.7 KIY67999.1 - 1e-07 31.7 1.1 2.6e-07 30.4 1.1 1.7 1 0 0 1 1 1 1 F-box-like HOOK PF05622.12 KIY68000.1 - 9.9e-59 199.2 53.6 9.9e-59 199.2 53.6 2.4 1 1 0 2 2 2 1 HOOK protein DUF4407 PF14362.6 KIY68000.1 - 0.0031 16.9 15.0 0.0031 16.9 15.0 5.0 1 1 5 6 6 6 2 Domain of unknown function (DUF4407) NYD-SP28_assoc PF14775.6 KIY68000.1 - 0.0033 17.5 19.0 0.074 13.2 2.9 4.9 3 0 0 3 3 3 3 Sperm tail C-terminal domain CEP63 PF17045.5 KIY68000.1 - 0.0044 17.0 20.1 0.0044 17.0 20.1 5.6 2 2 1 4 4 4 1 Centrosomal protein of 63 kDa Spc7 PF08317.11 KIY68000.1 - 0.0048 15.8 13.4 0.0048 15.8 13.4 5.4 2 2 2 5 5 5 2 Spc7 kinetochore protein DUF641 PF04859.12 KIY68000.1 - 0.0075 16.6 7.1 0.0075 16.6 7.1 6.9 3 3 5 8 8 8 2 Plant protein of unknown function (DUF641) DUF3800 PF12686.7 KIY68000.1 - 0.043 14.4 0.0 77 4.0 2.1 3.9 2 2 0 2 2 2 0 Protein of unknown function (DUF3800) Fez1 PF06818.15 KIY68000.1 - 4.3 7.7 82.4 0.33 11.4 11.4 5.2 2 2 2 4 4 4 0 Fez1 Surfac_D-trimer PF09006.11 KIY68000.1 - 6.2 6.8 0.0 6.2 6.8 0.0 6.0 7 1 1 8 8 8 0 Lung surfactant protein D coiled-coil trimerisation HSF_DNA-bind PF00447.17 KIY68001.1 - 4.5e-28 97.7 0.7 4.5e-28 97.7 0.7 1.6 2 0 0 2 2 2 1 HSF-type DNA-binding Use1 PF09753.9 KIY68001.1 - 0.0078 16.0 0.3 0.0097 15.7 0.3 1.2 1 0 0 1 1 1 1 Membrane fusion protein Use1 Leu_zip PF15294.6 KIY68001.1 - 0.027 14.0 0.1 0.036 13.6 0.1 1.2 1 0 0 1 1 1 0 Leucine zipper APG6_N PF17675.1 KIY68001.1 - 0.05 14.1 1.2 0.11 13.0 1.2 1.6 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF3450 PF11932.8 KIY68001.1 - 0.073 12.4 2.6 0.099 11.9 1.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) Gp58 PF07902.11 KIY68001.1 - 0.21 9.8 0.1 0.27 9.5 0.1 1.1 1 0 0 1 1 1 0 gp58-like protein KIX PF02172.16 KIY68001.1 - 0.23 11.7 2.5 6.2 7.2 0.1 2.9 2 2 1 3 3 3 0 KIX domain Snapin_Pallidin PF14712.6 KIY68001.1 - 0.69 10.4 4.2 0.48 10.9 1.7 2.1 2 1 0 2 2 2 0 Snapin/Pallidin Inhibitor_I66 PF16850.5 KIY68002.1 - 5.2e-05 23.1 0.0 8.5e-05 22.5 0.0 1.4 1 1 0 1 1 1 1 Peptidase inhibitor I66 RicinB_lectin_2 PF14200.6 KIY68002.1 - 0.00035 21.2 0.1 0.87 10.4 0.0 2.9 1 1 2 3 3 3 3 Ricin-type beta-trefoil lectin domain-like Aldo_ket_red PF00248.21 KIY68003.1 - 5.6e-42 143.9 0.0 4.5e-41 141.0 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family EzrA PF06160.12 KIY68004.1 - 0.0068 14.6 0.7 0.0097 14.1 0.7 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA DUF2353 PF09789.9 KIY68004.1 - 0.018 14.4 4.1 0.027 13.9 4.1 1.1 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) GATase PF00117.28 KIY68005.1 - 4.7e-07 29.8 0.0 8.2e-07 29.0 0.0 1.4 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Alpha-amylase PF00128.24 KIY68006.1 - 3.7e-49 168.1 0.3 5.2e-49 167.6 0.3 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.11 KIY68006.1 - 8.3e-10 38.8 0.0 1.7e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) Sugar_tr PF00083.24 KIY68007.1 - 2.7e-75 254.0 13.1 3.5e-75 253.6 13.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY68007.1 - 1e-20 74.0 27.0 1e-20 74.0 27.0 2.0 1 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KIY68007.1 - 0.003 16.1 5.5 0.003 16.1 5.5 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) DUF5325 PF17259.2 KIY68007.1 - 2.1 8.3 7.6 1.1 9.2 2.4 3.0 2 0 0 2 2 2 0 Family of unknown function (DUF5325) Acyl-CoA_dh_M PF02770.19 KIY68008.1 - 0.00072 19.7 0.0 0.0014 18.7 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_M PF02770.19 KIY68009.1 - 0.0019 18.3 0.0 0.0049 17.0 0.0 1.8 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cas_Csy2 PF09614.10 KIY68010.1 - 0.24 10.7 0.6 0.45 9.8 0.6 1.5 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csy2) 7tm_1 PF00001.21 KIY68012.1 - 2.5 7.4 6.7 3.8 6.8 6.7 1.3 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) GMC_oxred_N PF00732.19 KIY68013.1 - 4.4e-65 220.0 0.0 6.5e-65 219.4 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIY68013.1 - 1.4e-34 119.6 0.0 3e-34 118.6 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KIY68013.1 - 1.6e-06 27.5 0.1 2.4e-06 26.9 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KIY68013.1 - 6.6e-05 22.2 0.0 0.0048 16.0 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 KIY68013.1 - 0.0014 17.9 0.1 0.0034 16.7 0.1 1.6 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 KIY68013.1 - 0.023 13.9 0.0 0.041 13.1 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KIY68013.1 - 0.024 13.7 0.0 0.53 9.3 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.14 KIY68013.1 - 0.037 12.7 0.5 0.064 11.9 0.5 1.3 1 0 0 1 1 1 0 HI0933-like protein SUR7 PF06687.12 KIY68014.1 - 9.3e-16 58.1 10.8 1.5e-15 57.4 10.8 1.4 1 1 0 1 1 1 1 SUR7/PalI family Clc-like PF07062.12 KIY68014.1 - 0.00072 19.1 1.6 0.00072 19.1 1.6 2.1 2 0 0 2 2 2 1 Clc-like DUF805 PF05656.14 KIY68014.1 - 0.011 16.1 2.3 0.011 16.1 2.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF805) AHD PF17793.1 KIY68014.1 - 0.05 13.4 0.0 0.076 12.8 0.0 1.3 1 0 0 1 1 1 0 ANC1 homology domain (AHD) FLILHELTA PF10306.9 KIY68014.1 - 0.17 12.3 0.6 0.36 11.2 0.4 1.7 1 1 0 1 1 1 0 Hypothetical protein FLILHELTA LRR_9 PF14580.6 KIY68015.1 - 0.035 13.6 1.0 0.076 12.5 0.8 1.6 1 1 0 1 1 1 0 Leucine-rich repeat LRR_4 PF12799.7 KIY68015.1 - 0.038 14.4 4.1 2.1 8.9 3.2 2.6 1 1 0 2 2 2 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KIY68015.1 - 0.2 11.8 1.3 8 6.8 0.1 3.1 3 0 0 3 3 3 0 Leucine Rich repeat RL10P_insert PF17777.1 KIY68016.1 - 1.6e-22 79.3 0.0 2.7e-22 78.5 0.0 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 KIY68016.1 - 8.5e-20 70.8 0.0 1.2e-19 70.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 DUF3146 PF11344.8 KIY68016.1 - 0.041 13.6 0.1 0.073 12.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3146) RANK_CRD_2 PF18278.1 KIY68016.1 - 0.07 13.3 0.2 0.14 12.3 0.2 1.5 1 0 0 1 1 1 0 Receptor activator of the NF-KB cysteine-rich repeat domain 2 HEAT_2 PF13646.6 KIY68017.1 - 3.8e-34 116.9 1.6 2.2e-14 53.6 0.0 4.1 2 2 2 4 4 4 4 HEAT repeats HEAT_PBS PF03130.16 KIY68017.1 - 7.9e-22 75.7 0.9 0.0012 19.4 0.1 6.5 7 0 0 7 7 7 5 PBS lyase HEAT-like repeat HEAT PF02985.22 KIY68017.1 - 5.1e-13 48.1 0.2 0.027 14.7 0.0 5.8 5 0 0 5 5 5 3 HEAT repeat HEAT_EZ PF13513.6 KIY68017.1 - 0.00011 22.7 2.0 0.15 12.6 0.1 4.5 3 2 2 5 5 5 1 HEAT-like repeat Arm PF00514.23 KIY68017.1 - 0.00017 21.5 0.1 0.02 14.9 0.0 3.5 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat DUF3385 PF11865.8 KIY68017.1 - 0.0064 16.4 0.0 0.14 12.1 0.0 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF3385) Cnd1 PF12717.7 KIY68017.1 - 0.11 12.6 0.0 6.1 6.9 0.0 3.2 2 2 2 4 4 4 0 non-SMC mitotic condensation complex subunit 1 RTBV_P12 PF06361.11 KIY68017.1 - 0.14 12.5 0.5 3.9 7.9 0.0 2.5 3 0 0 3 3 3 0 Rice tungro bacilliform virus P12 protein MAS20 PF02064.15 KIY68019.1 - 0.05 13.7 0.6 0.25 11.5 0.4 2.3 2 0 0 2 2 2 0 MAS20 protein import receptor Lipase_3 PF01764.25 KIY68021.1 - 8.2e-26 90.6 0.0 1.2e-25 90.0 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KIY68021.1 - 0.0011 19.6 0.1 0.0017 19.0 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KIY68021.1 - 0.0016 18.1 0.0 0.002 17.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF3530 PF12048.8 KIY68021.1 - 0.0067 15.9 0.0 0.008 15.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3530) Thioesterase PF00975.20 KIY68021.1 - 0.031 14.4 0.0 0.049 13.7 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Hydrolase_4 PF12146.8 KIY68021.1 - 0.048 12.9 0.0 0.072 12.3 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 CdiA_C_tRNase PF18664.1 KIY68021.1 - 0.087 13.0 0.1 2.6 8.3 0.1 2.3 2 0 0 2 2 2 0 CdiA C-terminal tRNase domain LCAT PF02450.15 KIY68021.1 - 0.19 10.8 0.0 0.23 10.6 0.0 1.1 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase LIDHydrolase PF10230.9 KIY68021.1 - 0.22 11.0 0.0 0.33 10.5 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase TauD PF02668.16 KIY68022.1 - 4e-47 161.3 0.0 5.2e-47 160.9 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family F-box-like PF12937.7 KIY68024.1 - 4.4e-10 39.3 0.2 1.2e-09 37.9 0.2 1.8 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KIY68024.1 - 0.0085 16.5 4.7 0.31 11.5 1.2 4.1 4 0 0 4 4 4 1 Leucine Rich repeats (2 copies) TMF_TATA_bd PF12325.8 KIY68024.1 - 0.059 13.6 0.2 0.14 12.4 0.2 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding F-box-like_2 PF13013.6 KIY68024.1 - 0.063 13.3 0.0 0.2 11.6 0.0 1.9 1 0 0 1 1 1 0 F-box-like domain zf-HC5HC2H_2 PF13832.6 KIY68025.1 - 7.6e-17 61.5 9.5 7.6e-17 61.5 9.5 4.6 3 1 0 4 4 4 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KIY68025.1 - 7.7e-12 45.3 11.0 7.7e-12 45.3 11.0 5.6 4 2 1 5 5 5 1 PHD-like zinc-binding domain PHD PF00628.29 KIY68025.1 - 2.2e-08 33.8 11.6 2.2e-08 33.8 11.6 5.9 6 0 0 6 6 6 3 PHD-finger BAH PF01426.18 KIY68025.1 - 7.4e-08 32.3 0.1 2.2e-07 30.8 0.0 1.7 2 0 0 2 2 2 1 BAH domain zf-RING_7 PF02591.15 KIY68025.1 - 0.11 12.7 5.3 0.63 10.3 0.1 3.6 3 0 0 3 3 3 0 C4-type zinc ribbon domain Evr1_Alr PF04777.13 KIY68025.1 - 0.9 10.0 6.7 0.5 10.9 0.4 3.1 3 0 0 3 3 3 0 Erv1 / Alr family Glycos_transf_2 PF00535.26 KIY68027.1 - 1.8e-25 89.7 0.0 2.2e-25 89.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KIY68027.1 - 4.7e-10 39.7 0.0 9.7e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 KIY68027.1 - 0.00064 19.3 0.0 0.0014 18.1 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Thi4 PF01946.17 KIY68027.1 - 0.12 11.6 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Yuri_gagarin PF15934.5 KIY68028.1 - 0.021 14.6 4.1 0.032 14.1 3.0 1.8 1 1 0 1 1 1 0 Yuri gagarin BST2 PF16716.5 KIY68028.1 - 0.26 11.9 10.5 0.51 11.0 4.9 2.9 2 1 1 3 3 3 0 Bone marrow stromal antigen 2 Ntox28 PF15605.6 KIY68028.1 - 0.35 11.1 3.4 20 5.5 1.4 3.1 2 1 1 3 3 3 0 Bacterial toxin 28 FlxA PF14282.6 KIY68028.1 - 2.1 8.4 8.7 3.8 7.6 0.2 2.5 2 0 0 2 2 2 0 FlxA-like protein Ran_BP1 PF00638.18 KIY68029.1 - 1.2e-15 57.8 0.0 2.3e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain WLM PF08325.10 KIY68030.1 - 3.6e-40 138.1 0.2 1.5e-39 136.1 0.0 2.0 2 0 0 2 2 2 1 WLM domain ubiquitin PF00240.23 KIY68030.1 - 3.2e-08 33.2 0.0 7.9e-08 31.9 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family TBK1_ULD PF18396.1 KIY68030.1 - 0.013 15.4 0.0 0.028 14.3 0.0 1.6 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_2 PF14560.6 KIY68030.1 - 0.09 13.2 0.0 0.24 11.9 0.0 1.7 1 1 0 1 1 1 0 Ubiquitin-like domain DUF45 PF01863.17 KIY68030.1 - 0.37 10.8 3.5 7.6 6.5 0.2 3.0 2 2 1 3 3 3 0 Protein of unknown function DUF45 MutS_V PF00488.21 KIY68031.1 - 6.2e-64 215.5 0.1 1.2e-63 214.6 0.1 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KIY68031.1 - 2.3e-37 129.1 0.1 5.8e-37 127.8 0.1 1.7 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 KIY68031.1 - 3.5e-34 117.4 0.1 7.9e-34 116.3 0.1 1.6 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 KIY68031.1 - 2.3e-13 50.6 0.1 1.8e-12 47.7 0.0 2.5 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 KIY68031.1 - 0.0028 17.9 0.1 0.008 16.5 0.1 1.9 1 0 0 1 1 1 1 MutS family domain IV AAA_27 PF13514.6 KIY68031.1 - 0.021 14.4 0.0 0.066 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF2203 PF09969.9 KIY68031.1 - 0.07 13.9 0.0 9.4 7.0 0.0 3.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) AAA_23 PF13476.6 KIY68031.1 - 3.8 8.0 7.9 1.6 9.2 0.0 3.3 3 0 0 3 3 3 0 AAA domain Abhydrolase_1 PF00561.20 KIY68033.1 - 2.1e-15 57.0 0.0 1.1e-14 54.7 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIY68033.1 - 2.1e-09 38.3 0.1 2.9e-09 37.9 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIY68033.1 - 2.4e-09 36.8 0.0 0.00014 21.2 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Esterase PF00756.20 KIY68033.1 - 0.0011 18.7 0.0 0.0018 18.0 0.0 1.4 1 0 0 1 1 1 1 Putative esterase DLH PF01738.18 KIY68033.1 - 0.082 12.4 0.0 0.35 10.4 0.0 1.9 2 0 0 2 2 2 0 Dienelactone hydrolase family FMO-like PF00743.19 KIY68034.1 - 8.7e-23 80.5 0.5 8.6e-17 60.8 0.1 2.4 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KIY68034.1 - 6.9e-19 68.2 0.0 6.1e-18 65.1 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KIY68034.1 - 6.4e-16 58.4 0.0 4.8e-06 26.0 0.0 3.1 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KIY68034.1 - 9.8e-10 38.2 0.1 7.7e-07 28.7 0.0 3.0 3 0 0 3 3 3 1 FAD binding domain Pyr_redox PF00070.27 KIY68034.1 - 4.1e-09 36.9 1.4 0.0082 16.7 0.0 3.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIY68034.1 - 2.1e-08 34.2 0.0 1.5e-06 28.3 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KIY68034.1 - 3.2e-08 33.1 0.0 6.1e-07 28.9 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KIY68034.1 - 1.9e-07 31.0 0.0 0.0027 17.3 0.0 2.7 3 0 0 3 3 3 2 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 KIY68034.1 - 7.4e-06 25.4 0.1 0.00049 19.5 0.0 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.14 KIY68034.1 - 7.8e-06 24.8 0.0 0.00011 21.0 0.0 2.3 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.12 KIY68034.1 - 8e-06 25.1 0.4 0.0089 15.1 0.4 3.1 2 1 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 KIY68034.1 - 0.00012 22.1 0.3 0.017 15.1 0.0 3.2 2 1 1 3 3 3 1 FAD-NAD(P)-binding Shikimate_DH PF01488.20 KIY68034.1 - 0.00029 20.9 0.0 0.94 9.5 0.0 2.5 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 KIY68034.1 - 0.00055 19.9 0.5 0.6 10.0 0.1 2.3 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 KIY68034.1 - 0.00062 20.2 0.0 1.2 9.6 0.0 2.6 3 0 0 3 3 2 2 Putative NAD(P)-binding FAD_binding_2 PF00890.24 KIY68034.1 - 0.00089 18.4 0.1 0.0026 16.9 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain TrkA_N PF02254.18 KIY68034.1 - 0.0019 18.4 0.0 0.045 14.0 0.0 2.4 2 0 0 2 2 2 1 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 KIY68034.1 - 0.0021 17.6 0.0 0.0038 16.8 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Amino_oxidase PF01593.24 KIY68034.1 - 0.0037 16.6 0.0 0.41 9.9 0.0 3.0 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.21 KIY68034.1 - 0.0075 15.6 0.0 0.02 14.2 0.0 1.6 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.16 KIY68034.1 - 0.0093 15.6 0.2 0.089 12.4 0.0 2.4 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA SnoaL_2 PF12680.7 KIY68034.1 - 0.01 16.4 0.2 1.6 9.4 0.0 2.7 2 0 0 2 2 2 0 SnoaL-like domain FAD_oxidored PF12831.7 KIY68034.1 - 0.013 14.9 0.5 0.4 10.0 0.1 2.2 1 1 1 2 2 2 0 FAD dependent oxidoreductase IlvN PF07991.12 KIY68034.1 - 0.04 13.5 0.2 4.1 7.0 0.0 2.3 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Thi4 PF01946.17 KIY68034.1 - 0.077 12.2 0.1 3 7.0 0.0 2.5 2 0 0 2 2 2 0 Thi4 family Glu_dehyd_C PF16912.5 KIY68034.1 - 0.087 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus Trp_halogenase PF04820.14 KIY68034.1 - 0.15 10.9 0.2 1 8.1 0.2 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Utp14 PF04615.13 KIY68035.1 - 6.5e-188 626.8 67.2 6.5e-188 626.8 67.2 3.0 1 1 1 2 2 2 1 Utp14 protein AA_kinase PF00696.28 KIY68036.1 - 3.6e-36 125.0 0.0 9.7e-36 123.6 0.0 1.7 1 1 0 1 1 1 1 Amino acid kinase family ACT PF01842.25 KIY68036.1 - 3.1e-11 42.8 0.3 6e-06 25.9 0.1 2.6 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.6 KIY68036.1 - 7.1e-10 38.5 1.0 9.7e-07 28.5 0.3 3.0 3 0 0 3 3 3 2 ACT domain TFIIA_gamma_C PF02751.14 KIY68037.1 - 1.1e-22 79.9 0.8 1.8e-22 79.2 0.8 1.4 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.16 KIY68037.1 - 4.9e-16 58.5 0.5 7.3e-16 57.9 0.5 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain F-box-like PF12937.7 KIY68038.1 - 4.1e-05 23.4 0.8 0.00014 21.6 0.8 2.0 1 1 0 1 1 1 1 F-box-like F-box-like PF12937.7 KIY68039.1 - 0.06 13.3 1.3 0.17 11.8 1.3 1.9 1 0 0 1 1 1 0 F-box-like Glyco_hydro_47 PF01532.20 KIY68040.1 - 9.9e-115 384.0 0.0 5.8e-114 381.5 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 Methyltransf_23 PF13489.6 KIY68041.1 - 1.5e-14 54.2 0.0 2.5e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIY68041.1 - 1.9e-12 47.8 0.0 3.9e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIY68041.1 - 1.7e-11 44.6 0.0 3.2e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIY68041.1 - 3.6e-08 34.0 0.0 6.7e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIY68041.1 - 9.2e-05 22.3 0.0 0.00017 21.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KIY68041.1 - 0.054 13.0 0.0 0.1 12.1 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase small domain DUF5566 PF17721.1 KIY68041.1 - 0.06 13.6 0.1 0.1 12.9 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5566) Methyltransf_24 PF13578.6 KIY68041.1 - 0.074 14.1 0.0 0.17 13.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain COesterase PF00135.28 KIY68042.1 - 1e-73 249.0 0.0 1.5e-73 248.4 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 KIY68042.1 - 2.8e-05 23.7 0.1 8e-05 22.2 0.0 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family HAD PF12710.7 KIY68042.1 - 0.0017 18.8 0.3 0.11 12.9 0.0 2.6 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Abhydrolase_3 PF07859.13 KIY68042.1 - 0.05 13.4 0.0 0.089 12.6 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold rpo132 PF12415.8 KIY68045.1 - 0.14 11.5 0.0 0.48 9.8 0.0 1.9 1 0 0 1 1 1 0 Poxvirus DNA dependent RNA polymerase Methyltransf_23 PF13489.6 KIY68048.1 - 2e-11 44.0 0.0 3.9e-11 43.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIY68048.1 - 5.6e-11 43.1 0.0 1.5e-10 41.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIY68048.1 - 2.1e-10 41.1 0.0 4.6e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIY68048.1 - 5e-07 30.3 0.0 1.4e-06 28.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIY68048.1 - 0.0014 18.5 0.0 0.0052 16.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KIY68048.1 - 0.021 14.4 0.0 0.04 13.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_24 PF13578.6 KIY68048.1 - 0.055 14.5 0.0 0.11 13.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.17 KIY68048.1 - 0.15 11.5 0.0 0.3 10.5 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase CHAT PF12770.7 KIY68050.1 - 4.4e-40 137.9 0.3 6.7e-40 137.3 0.3 1.3 1 0 0 1 1 1 1 CHAT domain TPR_11 PF13414.6 KIY68050.1 - 3.4e-05 23.4 1.1 1.6 8.5 0.0 6.4 8 0 0 8 8 8 1 TPR repeat TPR_10 PF13374.6 KIY68050.1 - 0.00065 19.5 7.2 0.74 9.8 0.0 7.4 9 0 0 9 9 9 1 Tetratricopeptide repeat DUF2267 PF10025.9 KIY68050.1 - 0.0087 16.3 0.1 9.5 6.5 0.0 3.7 3 0 0 3 3 3 2 Uncharacterized conserved protein (DUF2267) TPR_14 PF13428.6 KIY68050.1 - 0.037 14.9 15.0 39 5.4 0.0 8.7 8 1 1 9 9 9 0 Tetratricopeptide repeat TPR_16 PF13432.6 KIY68050.1 - 0.56 10.9 10.6 14 6.4 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat KH_1 PF00013.29 KIY68053.1 - 6.5e-10 38.7 0.1 1.1e-07 31.6 0.0 2.5 2 1 0 2 2 2 2 KH domain RhoGEF PF00621.20 KIY68054.1 - 2.4e-65 220.2 0.0 1.9e-33 116.3 0.0 3.2 3 0 0 3 3 3 2 RhoGEF domain CNH PF00780.22 KIY68054.1 - 3.3e-59 200.8 0.0 4.9e-59 200.2 0.0 1.2 1 0 0 1 1 1 1 CNH domain PH_5 PF15405.6 KIY68054.1 - 4.7e-13 49.4 0.0 9.8e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain DEP PF00610.21 KIY68054.1 - 0.00011 22.1 0.0 0.00027 21.0 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) VWA_3_C PF18571.1 KIY68055.1 - 0.071 13.0 0.1 0.64 9.9 0.0 2.2 2 0 0 2 2 2 0 von Willebrand factor type A C-terminal domain Fungal_trans PF04082.18 KIY68056.1 - 3.6e-21 75.4 0.0 6.9e-21 74.5 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY68056.1 - 1.7e-07 31.3 10.3 3.5e-07 30.2 10.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HpcH_HpaI PF03328.14 KIY68058.1 - 1.4e-31 109.4 0.1 1.7e-31 109.1 0.1 1.2 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PK PF00224.21 KIY68058.1 - 0.0018 17.2 0.3 0.0036 16.2 0.2 1.5 1 1 0 1 1 1 1 Pyruvate kinase, barrel domain Yip1 PF04893.17 KIY68059.1 - 0.039 13.7 0.2 0.058 13.1 0.2 1.2 1 0 0 1 1 1 0 Yip1 domain Ndc1_Nup PF09531.10 KIY68059.1 - 0.057 12.1 5.1 0.091 11.4 5.1 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Phage_holin_2_4 PF16082.5 KIY68059.1 - 0.066 13.0 0.1 0.066 13.0 0.1 2.1 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like DUF4328 PF14219.6 KIY68059.1 - 0.089 12.3 0.3 0.16 11.5 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4328) TraL PF07178.11 KIY68059.1 - 0.32 11.5 0.4 0.58 10.7 0.4 1.3 1 0 0 1 1 1 0 TraL protein Beta-APP PF03494.13 KIY68059.1 - 2.5 8.0 12.8 0.12 12.2 6.4 2.0 2 0 0 2 2 2 0 Beta-amyloid peptide (beta-APP) SKG6 PF08693.10 KIY68059.1 - 6.7 6.2 7.9 0.47 9.9 1.9 2.2 2 0 0 2 2 2 0 Transmembrane alpha-helix domain RRM_1 PF00076.22 KIY68060.1 - 4.7e-06 26.3 0.0 7.9e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Btz PF09405.10 KIY68060.1 - 0.035 14.4 0.0 0.059 13.6 0.0 1.4 1 0 0 1 1 1 0 CASC3/Barentsz eIF4AIII binding Calcipressin PF04847.12 KIY68060.1 - 0.096 12.4 0.0 7.8 6.2 0.0 2.2 2 0 0 2 2 2 0 Calcipressin YbfN PF13982.6 KIY68061.1 - 0.087 13.1 0.2 0.19 12.0 0.2 1.5 1 0 0 1 1 1 0 YbfN-like lipoprotein DAO PF01266.24 KIY68064.1 - 4e-46 158.2 0.1 4.6e-46 158.0 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIY68064.1 - 2.9e-06 26.7 0.0 0.0017 17.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIY68064.1 - 4.4e-06 26.8 0.0 1.1e-05 25.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KIY68064.1 - 6.7e-06 25.4 0.1 0.042 12.9 0.1 2.1 2 0 0 2 2 2 2 FAD binding domain Amino_oxidase PF01593.24 KIY68064.1 - 2.8e-05 23.6 0.1 0.15 11.4 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 KIY68064.1 - 4.1e-05 24.1 0.0 0.0028 18.2 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KIY68064.1 - 0.0011 18.2 0.0 0.82 8.7 0.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KIY68064.1 - 0.0019 17.5 0.0 0.01 15.1 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KIY68064.1 - 0.0051 16.9 0.0 0.01 15.9 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.14 KIY68064.1 - 0.0053 15.5 0.0 1.6 7.3 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein K_oxygenase PF13434.6 KIY68064.1 - 0.029 13.5 0.0 0.078 12.1 0.0 1.6 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KIY68064.1 - 0.03 14.3 0.1 0.2 11.7 0.0 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding TrkA_N PF02254.18 KIY68064.1 - 0.048 13.9 0.0 0.092 13.0 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Thi4 PF01946.17 KIY68064.1 - 0.071 12.3 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Ank_4 PF13637.6 KIY68065.1 - 0.00011 22.6 0.6 4.1 8.1 0.1 4.4 3 1 2 5 5 5 2 Ankyrin repeats (many copies) SAP PF02037.27 KIY68065.1 - 0.0032 17.2 0.0 0.0055 16.4 0.0 1.4 1 0 0 1 1 1 1 SAP domain SnoaL_2 PF12680.7 KIY68065.1 - 0.17 12.6 0.5 53 4.5 0.0 3.2 2 1 1 3 3 3 0 SnoaL-like domain DUF4407 PF14362.6 KIY68067.1 - 0.055 12.8 0.3 0.066 12.5 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) F-box-like PF12937.7 KIY68068.1 - 0.0041 17.0 0.2 0.0097 15.8 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY68068.1 - 0.04 13.8 1.6 0.15 12.0 0.1 2.7 2 1 0 2 2 2 0 F-box domain DPBB_1 PF03330.18 KIY68069.1 - 7.4e-05 23.0 0.3 0.00016 21.9 0.3 1.7 1 1 0 1 1 1 1 Lytic transglycolase DUF2673 PF10880.8 KIY68069.1 - 0.13 12.4 0.2 0.19 11.9 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2673) 2-Hacid_dh_C PF02826.19 KIY68070.1 - 1.4e-52 177.6 0.0 1.7e-52 177.3 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 KIY68070.1 - 1.9e-05 24.9 0.0 4.3e-05 23.7 0.0 1.5 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh PF00389.30 KIY68070.1 - 0.01 15.5 0.0 0.013 15.2 0.0 1.1 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain IlvN PF07991.12 KIY68070.1 - 0.031 13.8 0.0 0.047 13.3 0.0 1.2 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain 2-Hacid_dh_C PF02826.19 KIY68071.1 - 2.9e-52 176.6 0.0 3.9e-52 176.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KIY68071.1 - 2.5e-14 53.1 0.0 3.1e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KIY68071.1 - 3.7e-05 23.9 0.0 7.9e-05 22.9 0.0 1.5 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 KIY68071.1 - 0.047 13.2 0.0 0.083 12.5 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain 2-Hacid_dh PF00389.30 KIY68072.1 - 4.5e-06 26.4 0.0 4.8e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Glyco_transf_49 PF13896.6 KIY68073.1 - 6.2e-66 223.0 3.2 8.5e-53 179.8 0.3 2.0 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Stomoxyn PF11585.8 KIY68073.1 - 0.043 13.8 0.0 0.15 12.1 0.0 1.9 1 0 0 1 1 1 0 Insect antimicrobial peptide, stomoxyn Glyco_tranf_2_4 PF13704.6 KIY68073.1 - 0.16 12.5 1.0 0.91 10.1 0.5 2.4 2 1 0 2 2 2 0 Glycosyl transferase family 2 Abhydrolase_6 PF12697.7 KIY68074.1 - 1.9e-06 28.6 0.1 2.6e-06 28.2 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Glyco_hydro_88 PF07470.13 KIY68075.1 - 1.2e-21 77.2 0.6 5e-21 75.1 0.3 1.8 1 1 0 1 1 1 1 Glycosyl Hydrolase Family 88 Rad60-SLD_2 PF13881.6 KIY68077.1 - 4.3e-12 46.1 0.0 5.8e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KIY68077.1 - 0.0097 15.6 0.0 0.031 14.0 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin family WD40 PF00400.32 KIY68080.1 - 3.6e-07 30.8 16.8 0.0044 17.8 0.2 5.6 6 1 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY68080.1 - 0.00029 21.1 0.1 0.25 11.7 0.0 3.4 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain CAP59_mtransfer PF11735.8 KIY68081.1 - 3.7e-73 246.2 0.0 4.5e-73 245.9 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 BcrAD_BadFG PF01869.20 KIY68082.1 - 5.6e-15 55.6 0.0 9.1e-15 54.9 0.0 1.4 1 1 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family DUF5593 PF18007.1 KIY68082.1 - 0.15 12.8 0.2 0.59 10.9 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5593) FGGY_N PF00370.21 KIY68082.1 - 0.18 11.3 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain Lyase_aromatic PF00221.19 KIY68083.1 - 4e-150 500.5 0.2 4e-150 500.5 0.2 1.3 2 0 0 2 2 2 1 Aromatic amino acid lyase zf-C2H2 PF00096.26 KIY68084.1 - 0.0001 22.5 2.8 0.0029 18.0 0.3 2.6 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIY68084.1 - 0.0023 18.6 1.7 0.23 12.4 0.2 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger AT_hook PF02178.19 KIY68084.1 - 0.84 9.7 23.9 1.5 8.9 4.1 4.3 4 0 0 4 4 4 0 AT hook motif Fcf1 PF04900.12 KIY68085.1 - 3.9e-38 129.8 2.2 6.3e-38 129.2 2.2 1.3 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 KIY68085.1 - 3.3e-13 49.9 0.5 4e-12 46.5 0.0 2.0 2 0 0 2 2 2 1 PIN like domain Porin_OmpG PF09381.10 KIY68085.1 - 0.21 11.3 0.0 0.29 10.9 0.0 1.1 1 0 0 1 1 1 0 Outer membrane protein G (OmpG) RNA_lig_T4_1 PF09511.10 KIY68086.1 - 3.6e-81 272.2 0.0 6.8e-81 271.3 0.0 1.5 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.11 KIY68086.1 - 5.4e-27 94.9 0.0 1.1e-26 93.9 0.0 1.5 1 0 0 1 1 1 1 tRNA ligase kinase domain tRNA_lig_CPD PF08302.11 KIY68086.1 - 2.4e-19 69.8 0.0 6.1e-19 68.5 0.0 1.6 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain AAA_17 PF13207.6 KIY68086.1 - 0.0014 19.0 1.1 0.062 13.7 0.0 3.4 4 0 0 4 4 4 1 AAA domain KTI12 PF08433.10 KIY68086.1 - 0.0044 16.5 1.2 0.053 13.0 0.1 2.7 2 1 1 3 3 3 1 Chromatin associated protein KTI12 AAA_18 PF13238.6 KIY68086.1 - 0.036 14.6 0.0 0.12 12.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain DUF4531 PF15041.6 KIY68086.1 - 0.091 12.9 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4531) Cytochrom_B_C PF00032.17 KIY68088.1 - 0.3 11.4 4.8 0.1 12.9 0.7 2.4 2 1 0 2 2 2 0 Cytochrome b(C-terminal)/b6/petD CPSase_L_D2 PF02786.17 KIY68089.1 - 7.2e-100 332.8 0.1 1e-75 253.9 0.0 2.5 3 0 0 3 3 3 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 KIY68089.1 - 4.1e-42 143.4 0.2 9.6e-42 142.2 0.2 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 KIY68089.1 - 4.7e-14 52.3 0.0 9.6e-06 25.3 0.0 2.7 3 0 0 3 3 3 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KIY68089.1 - 9.4e-12 44.9 0.0 5.3e-05 22.8 0.0 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 KIY68089.1 - 9.8e-08 31.8 0.0 0.0014 18.3 0.0 2.8 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_5 PF13549.6 KIY68089.1 - 5.8e-06 25.9 0.0 0.016 14.6 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_3 PF02655.14 KIY68089.1 - 0.0015 18.6 0.0 0.093 12.8 0.0 2.5 2 0 0 2 2 2 1 ATP-grasp domain MGS PF02142.22 KIY68089.1 - 0.0053 16.9 0.0 0.045 14.0 0.0 2.6 2 0 0 2 2 2 1 MGS-like domain Peptidase_M17_N PF02789.17 KIY68089.1 - 0.082 12.8 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 Cytosol aminopeptidase family, N-terminal domain APH PF01636.23 KIY68090.1 - 2.6e-39 135.6 0.0 3.5e-39 135.2 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KIY68090.1 - 7.1e-05 22.5 0.0 0.00024 20.8 0.0 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase EcKinase PF02958.20 KIY68090.1 - 0.00027 20.4 0.0 0.00041 19.8 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Sel1 PF08238.12 KIY68091.1 - 3.4e-23 81.6 28.9 3.7e-05 24.3 0.1 9.2 9 1 0 9 9 9 6 Sel1 repeat TPR_6 PF13174.6 KIY68091.1 - 0.00031 21.2 5.8 31 5.5 0.0 6.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 KIY68091.1 - 0.0057 16.6 5.4 0.034 14.2 0.3 4.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KIY68091.1 - 0.057 14.1 19.0 0.065 13.9 1.4 5.2 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 KIY68091.1 - 0.073 13.3 8.6 5.1 7.6 1.4 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 KIY68091.1 - 8.1 6.5 13.4 4.4 7.3 0.6 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 KIY68091.1 - 9 6.7 16.8 3.2 8.1 0.5 4.8 5 1 0 5 5 5 0 Tetratricopeptide repeat RNase_T PF00929.24 KIY68092.1 - 1.7e-32 113.2 0.0 2e-32 113.0 0.0 1.0 1 0 0 1 1 1 1 Exonuclease DUF5051 PF16473.5 KIY68092.1 - 0.00072 19.6 0.0 0.0011 18.9 0.0 1.3 1 1 0 1 1 1 1 3' exoribonuclease, RNase T-like PPTA PF01239.22 KIY68093.1 - 7.8e-11 41.3 20.3 2.6e-05 23.8 0.6 4.8 4 0 0 4 4 4 4 Protein prenyltransferase alpha subunit repeat MIF4G PF02854.19 KIY68094.1 - 5.8e-56 189.5 4.9 1.1e-55 188.6 4.9 1.5 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.8 KIY68094.1 - 5.9e-16 58.4 0.0 1.7e-15 57.0 0.0 1.8 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 MA3 PF02847.17 KIY68094.1 - 1.2e-05 25.2 0.1 1.2e-05 25.2 0.1 2.3 3 0 0 3 3 3 1 MA3 domain F-box-like PF12937.7 KIY68095.1 - 3.3e-05 23.7 2.9 0.00011 22.1 2.9 1.9 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KIY68095.1 - 9.7 6.2 8.8 0.76 9.7 1.7 2.8 3 0 0 3 3 3 0 F-box domain O-FucT PF10250.9 KIY68096.1 - 1.4e-12 48.0 0.0 3e-12 46.9 0.0 1.5 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Band_7 PF01145.25 KIY68096.1 - 0.047 13.7 0.0 0.55 10.2 0.0 2.2 2 0 0 2 2 2 0 SPFH domain / Band 7 family SWIB PF02201.18 KIY68097.1 - 5.5e-27 93.5 0.2 9.3e-27 92.7 0.2 1.4 1 0 0 1 1 1 1 SWIB/MDM2 domain Mucin PF01456.17 KIY68097.1 - 0.006 16.6 0.4 0.0083 16.1 0.4 1.2 1 0 0 1 1 1 1 Mucin-like glycoprotein PI3K_1B_p101 PF10486.9 KIY68097.1 - 0.014 13.2 6.2 0.016 13.1 6.2 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit CDC45 PF02724.14 KIY68097.1 - 0.4 8.9 20.9 0.61 8.3 20.9 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF1179 PF06678.11 KIY68097.1 - 4 7.5 6.1 10 6.2 6.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1179) GREB1 PF15782.5 KIY68097.1 - 4 4.4 7.3 4.6 4.2 7.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer MIF4G PF02854.19 KIY68098.1 - 2.5e-84 282.2 4.3 8.6e-50 169.3 2.7 3.2 3 0 0 3 3 3 3 MIF4G domain eIF_4G1 PF12152.8 KIY68098.1 - 3.2e-11 43.2 0.0 6.9e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 zf-CCCH_4 PF18044.1 KIY68098.1 - 0.0002 21.1 12.2 0.015 15.1 3.3 3.4 3 0 0 3 3 3 2 CCCH-type zinc finger MA3 PF02847.17 KIY68098.1 - 0.029 14.3 0.1 0.29 11.1 0.0 2.7 2 0 0 2 2 2 0 MA3 domain DUF4551 PF15087.6 KIY68098.1 - 0.077 11.8 6.4 0.16 10.8 6.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF4872 PF16169.5 KIY68098.1 - 0.15 11.8 0.0 0.61 9.8 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4872) C2 PF00168.30 KIY68099.1 - 1.3e-82 272.7 0.3 1.1e-21 77.1 0.1 5.7 6 0 0 6 6 6 5 C2 domain SMP_LBD PF17047.5 KIY68099.1 - 0.01 15.3 0.0 0.17 11.3 0.0 2.2 1 1 0 1 1 1 0 Synaptotagmin-like mitochondrial-lipid-binding domain Nucleo_P87 PF07267.11 KIY68100.1 - 4 6.2 8.9 4.4 6.1 8.9 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Arrestin_C PF02752.22 KIY68101.1 - 1.7e-14 54.4 0.3 5.8e-14 52.7 0.3 2.0 1 1 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KIY68101.1 - 1.6e-08 34.8 0.0 1.5e-07 31.6 0.0 2.5 3 1 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 KIY68101.1 - 0.0022 17.8 0.0 0.0055 16.4 0.0 1.6 1 0 0 1 1 1 1 Arrestin_N terminal like Rb_C PF08934.10 KIY68101.1 - 0.058 13.2 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Rb C-terminal domain DUF3830 PF12903.7 KIY68102.1 - 0.099 12.3 0.0 0.14 11.8 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3830) DUF1177 PF06675.11 KIY68102.1 - 0.11 11.3 0.0 0.63 8.8 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1177) Abhydrolase_3 PF07859.13 KIY68103.1 - 1e-38 133.3 0.0 4.3e-33 114.9 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KIY68103.1 - 4e-08 32.5 0.0 1.1e-07 31.1 0.0 1.6 2 0 0 2 2 2 1 Steryl acetyl hydrolase COesterase PF00135.28 KIY68103.1 - 0.17 10.8 0.1 0.38 9.6 0.0 1.6 2 0 0 2 2 2 0 Carboxylesterase family F-box-like PF12937.7 KIY68104.1 - 9.7e-07 28.6 0.2 2.9e-06 27.1 0.2 1.9 1 0 0 1 1 1 1 F-box-like STAS_2 PF13466.6 KIY68104.1 - 0.013 15.8 1.6 0.02 15.2 0.1 2.1 2 0 0 2 2 2 0 STAS domain F-box-like PF12937.7 KIY68105.1 - 3.3e-06 26.9 1.7 8e-06 25.7 0.9 2.2 2 0 0 2 2 2 1 F-box-like STAS_2 PF13466.6 KIY68105.1 - 0.04 14.3 0.9 0.12 12.7 0.0 2.2 2 0 0 2 2 2 0 STAS domain Aldo_ket_red PF00248.21 KIY68109.1 - 1.5e-42 145.8 0.2 1.5e-40 139.2 0.2 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family VitK2_biosynth PF02621.14 KIY68109.1 - 0.098 12.2 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Menaquinone biosynthesis Cu_bind_like PF02298.17 KIY68110.1 - 0.0014 18.6 4.2 0.27 11.3 0.6 3.5 2 2 0 2 2 2 2 Plastocyanin-like domain Copper-bind PF00127.20 KIY68110.1 - 0.0019 18.6 1.6 0.2 12.1 0.0 3.0 2 2 0 2 2 2 2 Copper binding proteins, plastocyanin/azurin family Strep_pep PF14404.6 KIY68110.1 - 0.0044 17.2 0.2 2.8 8.3 0.1 2.5 2 0 0 2 2 2 2 Ribosomally synthesized peptide in Streptomyces species Aldo_ket_red PF00248.21 KIY68111.1 - 4.9e-64 216.4 0.1 5.8e-64 216.1 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family SNF2_N PF00176.23 KIY68112.1 - 1.2e-68 231.4 1.6 2.4e-68 230.4 0.3 1.8 1 1 1 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KIY68112.1 - 1.4e-18 67.2 0.0 3.5e-18 66.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KIY68112.1 - 0.00073 19.3 0.3 0.018 14.8 0.0 2.9 2 1 0 2 2 2 1 DEAD/DEAH box helicase FAM76 PF16046.5 KIY68112.1 - 0.12 11.7 4.6 0.21 10.9 0.3 2.4 2 0 0 2 2 2 0 FAM76 protein HypA PF01155.19 KIY68112.1 - 0.6 10.1 5.2 0.65 10.0 1.8 2.7 3 1 0 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF1272 PF06906.11 KIY68112.1 - 1.8 8.7 4.6 3.6 7.7 1.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) CLN3 PF02487.17 KIY68113.1 - 4.6e-127 424.4 7.0 8.3e-127 423.5 7.0 1.4 1 1 0 1 1 1 1 CLN3 protein MFS_1 PF07690.16 KIY68113.1 - 0.15 10.9 19.1 0.23 10.3 18.5 1.7 1 1 1 2 2 2 0 Major Facilitator Superfamily F-box-like PF12937.7 KIY68114.1 - 1.6e-07 31.1 1.0 6.1e-07 29.2 0.3 2.4 2 0 0 2 2 2 1 F-box-like LRR_8 PF13855.6 KIY68114.1 - 0.1 12.4 1.0 24 4.8 0.1 3.1 3 0 0 3 3 3 0 Leucine rich repeat Fungal_trans PF04082.18 KIY68115.1 - 2.4e-07 30.1 0.0 5.3e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain TB2_DP1_HVA22 PF03134.19 KIY68116.1 - 1.2e-27 95.6 4.3 2.3e-27 94.7 4.3 1.5 1 0 0 1 1 1 1 TB2/DP1, HVA22 family GDP_Man_Dehyd PF16363.5 KIY68117.1 - 1.7e-158 527.4 0.0 1.9e-158 527.2 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KIY68117.1 - 2.8e-73 246.3 0.0 3.8e-73 245.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KIY68117.1 - 0.00013 21.2 0.0 0.00021 20.5 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KIY68117.1 - 0.0041 16.3 0.0 0.0068 15.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 KIY68117.1 - 0.078 12.5 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family NAD_binding_10 PF13460.6 KIY68117.1 - 0.12 12.2 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding CoaE PF01121.20 KIY68118.1 - 1.4e-63 213.8 0.0 1.8e-63 213.5 0.0 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 KIY68118.1 - 7.8e-05 23.2 0.3 0.00091 19.8 0.3 2.1 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KIY68118.1 - 0.0026 18.0 0.1 0.046 14.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 KIY68118.1 - 0.014 15.8 0.2 0.13 12.7 0.2 2.1 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KIY68118.1 - 0.018 15.2 0.2 0.27 11.4 0.2 2.2 1 1 0 1 1 1 0 AAA domain RNA_GG_bind PF10258.9 KIY68118.1 - 0.19 11.8 0.0 0.61 10.2 0.0 1.8 2 0 0 2 2 2 0 PHAX RNA-binding domain Far-17a_AIG1 PF04750.14 KIY68120.1 - 2.6e-28 98.7 5.1 3.1e-28 98.5 5.1 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein DUF4870 PF09685.10 KIY68120.1 - 0.063 13.4 2.0 0.15 12.2 2.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4870) Trep_Strep PF09605.10 KIY68120.1 - 0.098 12.6 7.3 0.084 12.8 5.5 1.7 2 0 0 2 2 2 0 Hypothetical bacterial integral membrane protein (Trep_Strep) DUF1440 PF07274.12 KIY68120.1 - 0.17 12.3 1.9 0.22 11.9 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1440) Glyco_hydro_7 PF00840.20 KIY68121.1 - 9.5e-208 690.2 17.6 1.1e-207 690.0 17.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Sec62 PF03839.16 KIY68122.1 - 1.3e-53 181.7 2.7 3.2e-53 180.4 2.7 1.5 1 1 0 1 1 1 1 Translocation protein Sec62 DUF3413 PF11893.8 KIY68122.1 - 1.4 8.0 6.3 2.2 7.4 6.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3413) MFS_1 PF07690.16 KIY68125.1 - 1.1e-16 60.7 40.7 1.7e-16 60.1 40.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 KIY68125.1 - 1.3e-13 51.0 6.5 1.3e-13 51.0 6.5 2.3 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 CPP1-like PF11833.8 KIY68125.1 - 5.7 6.6 8.8 2.3 7.8 3.5 2.4 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like ArgJ PF01960.18 KIY68126.1 - 5.3e-145 482.9 3.9 6.1e-145 482.7 3.9 1.0 1 0 0 1 1 1 1 ArgJ family ddrB-ParB PF18763.1 KIY68126.1 - 0.07 13.2 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 ddrB-like ParB superfamily domain RhoGAP PF00620.27 KIY68127.1 - 1e-07 31.9 0.0 2.1e-07 30.9 0.0 1.5 1 1 0 1 1 1 1 RhoGAP domain ADH_zinc_N PF00107.26 KIY68128.1 - 3.4e-26 91.8 0.5 5e-26 91.2 0.5 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KIY68128.1 - 1.6e-15 58.3 0.0 2.6e-15 57.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIY68128.1 - 1.4e-07 31.4 0.0 2.8e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 KIY68128.1 - 4.4e-07 29.6 0.2 6e-07 29.2 0.2 1.1 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_N_2 PF16884.5 KIY68128.1 - 0.032 14.1 0.0 0.081 12.8 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 KIY68129.1 - 1.4e-26 93.0 0.2 2.1e-26 92.4 0.2 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KIY68129.1 - 2.7e-18 67.3 0.0 5.6e-18 66.3 0.0 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIY68129.1 - 4.8e-06 26.4 0.0 1.2e-05 25.2 0.0 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 KIY68129.1 - 0.071 13.0 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase G-alpha PF00503.20 KIY68130.1 - 5.4e-105 351.4 0.0 6.4e-105 351.2 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KIY68130.1 - 2.3e-12 46.7 0.0 2.6e-09 36.8 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 KIY68130.1 - 0.0008 19.6 0.0 1.5 9.1 0.0 2.7 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 KIY68130.1 - 0.0039 16.8 0.0 0.29 10.7 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain TniB PF05621.11 KIY68130.1 - 0.026 13.9 0.0 0.051 13.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein Gtr1_RagA PF04670.12 KIY68130.1 - 0.06 12.7 0.0 4 6.7 0.0 2.3 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region DUF4410 PF14366.6 KIY68133.1 - 0.12 12.3 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4410) TPR_19 PF14559.6 KIY68134.1 - 2.1e-10 41.0 3.0 0.00012 22.5 0.1 3.9 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 KIY68134.1 - 7.5e-09 35.7 1.6 0.014 16.2 0.2 4.1 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 KIY68134.1 - 7e-07 29.8 1.2 0.038 14.7 0.0 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 KIY68134.1 - 2.4e-06 27.6 3.9 0.073 13.2 0.1 3.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 KIY68134.1 - 6.2e-05 22.9 0.0 0.068 13.4 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 KIY68134.1 - 0.00013 21.8 3.0 0.2 11.8 0.0 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 KIY68134.1 - 0.00051 19.7 0.0 0.28 11.1 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 KIY68134.1 - 0.00058 20.3 2.5 0.035 14.8 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 KIY68134.1 - 0.018 14.2 2.6 0.04 13.1 2.6 1.6 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_17 PF13431.6 KIY68134.1 - 0.021 15.2 1.9 6.2 7.4 0.1 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat CotJB PF12652.7 KIY68134.1 - 0.024 14.9 0.2 0.13 12.5 0.1 2.3 1 1 1 2 2 2 0 CotJB protein TPR_12 PF13424.6 KIY68134.1 - 0.033 14.5 2.2 2 8.8 0.5 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 KIY68134.1 - 0.094 12.8 0.8 6.8 7.0 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat HBM PF16591.5 KIY68134.1 - 0.2 11.0 2.0 3.7 6.9 0.0 2.6 2 1 0 3 3 3 0 Helical bimodular sensor domain BTB PF00651.31 KIY68135.1 - 0.00025 21.3 0.0 0.00061 20.0 0.0 1.7 2 0 0 2 2 2 1 BTB/POZ domain Skp1_POZ PF03931.15 KIY68135.1 - 0.13 12.4 0.0 0.32 11.2 0.0 1.6 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain Urm1 PF09138.11 KIY68136.1 - 1.2e-37 128.1 0.1 1.4e-37 128.0 0.1 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 KIY68136.1 - 1.9e-06 28.4 0.0 2.4e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 ThiS family ThiS-like PF14453.6 KIY68136.1 - 0.021 14.9 0.3 0.076 13.1 0.0 2.0 2 0 0 2 2 2 0 ThiS-like ubiquitin DHHA2 PF02833.14 KIY68137.1 - 3.4e-28 98.6 0.0 5.3e-28 98.0 0.0 1.3 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.20 KIY68137.1 - 7.6e-12 45.4 0.0 1.5e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 DHH family STAG PF08514.11 KIY68138.1 - 3.8e-34 117.0 0.1 3.8e-34 117.0 0.1 2.8 2 1 1 3 3 3 1 STAG domain HEAT_2 PF13646.6 KIY68138.1 - 0.00017 21.9 0.0 0.00086 19.7 0.0 2.4 1 0 0 1 1 1 1 HEAT repeats YL1 PF05764.13 KIY68138.1 - 0.0016 18.6 0.0 0.0016 18.6 0.0 6.9 5 3 1 6 6 6 1 YL1 nuclear protein HEAT PF02985.22 KIY68138.1 - 0.0035 17.5 0.0 0.27 11.6 0.0 3.7 2 0 0 2 2 2 1 HEAT repeat RTP1_C1 PF10363.9 KIY68138.1 - 0.007 16.5 0.0 0.021 15.0 0.0 1.8 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 1 MIT PF04212.18 KIY68140.1 - 0.0055 16.7 0.2 0.024 14.7 0.2 1.9 1 1 0 1 1 1 1 MIT (microtubule interacting and transport) domain PKcGMP_CC PF16808.5 KIY68140.1 - 0.012 15.4 0.3 0.023 14.5 0.3 1.4 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Lant_dehydr_C PF14028.6 KIY68140.1 - 0.049 13.2 0.9 0.1 12.1 0.9 1.4 1 0 0 1 1 1 0 Lantibiotic biosynthesis dehydratase C-term HMMR_N PF15905.5 KIY68140.1 - 0.05 13.1 4.8 0.13 11.7 4.8 1.7 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal UPF0242 PF06785.11 KIY68140.1 - 0.34 11.0 4.4 0.54 10.3 4.4 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF641 PF04859.12 KIY68140.1 - 0.55 10.6 5.0 5.1 7.4 0.3 2.3 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) HVSL PF09749.9 KIY68141.1 - 2.7e-47 161.3 0.0 3.1e-47 161.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein 2_5_RNA_ligase2 PF13563.6 KIY68141.1 - 1e-09 38.5 0.0 1.6e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.16 KIY68141.1 - 0.0023 18.1 0.2 0.0077 16.4 0.0 2.0 2 0 0 2 2 2 1 LigT like Phosphoesterase Methyltransf_16 PF10294.9 KIY68142.1 - 6.7e-14 52.0 0.0 9.3e-14 51.5 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Nif11 PF07862.11 KIY68142.1 - 0.034 14.5 0.1 0.11 12.8 0.1 1.9 2 0 0 2 2 2 0 Nif11 domain Glutaredoxin PF00462.24 KIY68143.1 - 7.5e-21 74.1 0.0 4e-18 65.4 0.0 2.3 2 0 0 2 2 2 2 Glutaredoxin Thioredoxin PF00085.20 KIY68143.1 - 1.7e-13 50.5 0.0 4.2e-13 49.2 0.0 1.6 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.6 KIY68143.1 - 7.2e-06 26.2 0.0 0.0006 20.1 0.0 2.4 1 1 1 2 2 2 1 Thioredoxin-like HyaE PF07449.11 KIY68143.1 - 0.00011 22.1 0.0 0.0012 18.8 0.0 2.5 2 1 0 2 2 2 1 Hydrogenase-1 expression protein HyaE SH3BGR PF04908.15 KIY68143.1 - 0.005 17.0 0.0 0.016 15.4 0.0 1.8 1 1 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Thioredoxin_2 PF13098.6 KIY68143.1 - 0.0056 17.1 0.0 0.14 12.6 0.0 2.6 1 1 1 2 2 2 1 Thioredoxin-like domain Thioredoxin_3 PF13192.6 KIY68143.1 - 0.0073 16.3 0.1 0.071 13.2 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin domain Big_4 PF07532.11 KIY68144.1 - 0.032 14.0 1.3 0.074 12.8 1.3 1.6 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 4) Promethin PF16015.5 KIY68145.1 - 3.4e-07 30.2 22.8 5.2e-07 29.6 22.8 1.3 1 0 0 1 1 1 1 Promethin DUF2070 PF09843.9 KIY68145.1 - 1.8 6.8 9.4 2.1 6.5 9.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Transp_cyt_pur PF02133.15 KIY68146.1 - 2.5e-88 296.8 37.8 3.1e-88 296.5 37.8 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin TrbC PF04956.13 KIY68146.1 - 0.003 17.8 2.7 0.014 15.6 2.7 2.2 1 0 0 1 1 1 1 TrbC/VIRB2 family MFS_1 PF07690.16 KIY68147.1 - 2e-47 161.9 59.6 2.1e-47 161.8 55.0 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KIY68147.1 - 5.4e-16 58.1 21.2 6.8e-16 57.8 21.1 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KIY68147.1 - 5.1e-12 45.4 13.4 5.1e-12 45.4 13.4 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter Fungal_trans PF04082.18 KIY68148.1 - 1.3e-30 106.4 0.0 1.9e-30 105.8 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY68148.1 - 0.00052 20.1 6.0 0.0012 19.0 6.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mating_C PF12737.7 KIY68148.1 - 0.13 11.4 1.6 0.24 10.6 1.6 1.3 1 0 0 1 1 1 0 C-terminal domain of homeodomain 1 Lactamase_B_2 PF12706.7 KIY68150.1 - 6.9e-34 117.1 0.3 1.4e-33 116.1 0.3 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KIY68150.1 - 1.6e-14 54.2 0.0 3.6e-14 53.0 0.0 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KIY68150.1 - 9e-05 22.6 0.8 0.00049 20.2 0.1 2.5 2 2 1 3 3 3 1 Metallo-beta-lactamase superfamily TLP1_add_C PF18313.1 KIY68150.1 - 0.0097 15.8 0.0 0.022 14.7 0.0 1.6 1 0 0 1 1 1 1 Thiolase-like protein type 1 additional C-terminal domain DUF3533 PF12051.8 KIY68151.1 - 1.2e-82 277.9 14.3 1.5e-82 277.6 14.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) Peptidase_M43 PF05572.13 KIY68152.1 - 2.4e-16 60.0 0.5 2.4e-16 60.0 0.5 1.6 2 0 0 2 2 2 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 KIY68152.1 - 8.9e-09 35.8 0.3 1.3e-08 35.2 0.3 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 KIY68152.1 - 5.2e-07 30.2 0.0 1e-06 29.2 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KIY68152.1 - 0.0013 18.6 0.1 0.0016 18.4 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KIY68152.1 - 0.0087 15.7 1.9 0.014 15.1 0.4 1.9 1 1 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 KIY68152.1 - 0.026 14.4 0.0 0.041 13.7 0.0 1.4 1 1 0 1 1 1 0 Matrixin Metallopep PF12044.8 KIY68152.1 - 0.037 12.6 0.1 0.055 12.1 0.1 1.2 1 0 0 1 1 1 0 Putative peptidase family DUF4953 PF16313.5 KIY68152.1 - 0.048 12.9 1.5 0.053 12.7 0.3 1.6 2 0 0 2 2 2 0 Met-zincin zf-C2H2 PF00096.26 KIY68153.1 - 1.6e-07 31.4 9.7 0.00033 21.0 2.4 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIY68153.1 - 2.5e-06 27.9 11.2 0.0048 17.6 1.9 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KIY68153.1 - 1.6e-05 25.1 9.7 0.0001 22.5 1.1 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_11 PF16622.5 KIY68153.1 - 0.0097 15.6 0.2 0.0097 15.6 0.2 2.4 2 0 0 2 2 2 1 zinc-finger C2H2-type zf-met PF12874.7 KIY68153.1 - 0.013 15.9 4.9 0.053 13.9 0.5 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 KIY68153.1 - 0.019 14.9 9.2 0.023 14.6 3.7 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type C1_1 PF00130.22 KIY68153.1 - 0.048 13.5 2.2 0.12 12.3 2.2 1.7 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2H2_jaz PF12171.8 KIY68153.1 - 0.067 13.5 0.2 0.067 13.5 0.2 2.0 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KIY68153.1 - 0.067 13.0 0.2 0.067 13.0 0.2 3.1 3 0 0 3 3 2 0 C2H2-type zinc-finger domain zf-SNAP50_C PF12251.8 KIY68153.1 - 0.14 11.8 2.9 0.18 11.4 2.9 1.2 1 0 0 1 1 1 0 snRNA-activating protein of 50kDa MW C terminal zf-C2H2_6 PF13912.6 KIY68153.1 - 0.43 10.6 5.8 3.6 7.7 1.1 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 KIY68153.1 - 0.66 10.1 4.9 19 5.4 1.6 2.9 3 0 0 3 3 3 0 Zinc ribbon domain zf-C2H2_2 PF12756.7 KIY68153.1 - 1.4 9.3 5.3 3 8.2 0.6 2.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Actin_micro PF17003.5 KIY68153.1 - 2.2 7.4 3.1 11 5.1 0.3 2.0 1 1 1 2 2 2 0 Putative actin-like family zf-HC5HC2H PF13771.6 KIY68154.1 - 2.3e-06 27.8 2.4 4.7e-06 26.8 2.4 1.6 1 1 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 KIY68154.1 - 3.8e-05 23.8 2.6 7.3e-05 22.9 2.6 1.6 1 1 0 1 1 1 1 PHD-zinc-finger like domain zf-rbx1 PF12678.7 KIY68154.1 - 0.056 13.7 0.6 0.13 12.5 0.6 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain FANCL_C PF11793.8 KIY68154.1 - 0.12 12.6 0.8 0.21 11.8 0.8 1.3 1 0 0 1 1 1 0 FANCL C-terminal domain CHAT PF12770.7 KIY68155.1 - 1e-34 120.3 0.0 2.3e-34 119.2 0.0 1.6 1 0 0 1 1 1 1 CHAT domain TPR_10 PF13374.6 KIY68155.1 - 2.5e-23 81.2 37.1 0.03 14.2 0.4 17.0 18 0 0 18 18 18 9 Tetratricopeptide repeat TPR_12 PF13424.6 KIY68155.1 - 2.9e-13 49.9 30.2 0.17 12.2 0.0 14.8 13 3 2 17 17 17 5 Tetratricopeptide repeat TPR_8 PF13181.6 KIY68155.1 - 2.8e-07 30.2 8.2 57 4.3 0.0 12.0 15 0 0 15 15 15 0 Tetratricopeptide repeat TPR_11 PF13414.6 KIY68155.1 - 5.6e-06 25.9 1.6 1.6 8.5 0.0 8.6 10 0 0 10 10 10 1 TPR repeat TPR_2 PF07719.17 KIY68155.1 - 7.8e-05 22.5 17.6 40 4.7 0.0 12.2 16 0 0 16 16 16 0 Tetratricopeptide repeat TPR_17 PF13431.6 KIY68155.1 - 0.017 15.5 0.0 23 5.7 0.0 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat STAT2_C PF12188.8 KIY68155.1 - 0.018 14.9 0.2 0.45 10.5 0.0 3.2 3 0 0 3 3 3 0 Signal transducer and activator of transcription 2 C terminal TPR_6 PF13174.6 KIY68155.1 - 0.075 13.7 1.7 26 5.7 0.0 5.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 KIY68155.1 - 1 9.5 19.3 9.3 6.5 0.0 9.5 11 0 0 11 11 11 0 Tetratricopeptide repeat CHAT PF12770.7 KIY68156.1 - 5.4e-41 140.9 0.3 7.3e-41 140.5 0.3 1.1 1 0 0 1 1 1 1 CHAT domain DUF627 PF04781.12 KIY68156.1 - 0.051 13.6 0.0 0.58 10.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF627) Melibiase_2 PF16499.5 KIY68157.1 - 5e-19 68.6 0.3 3.6e-11 42.8 0.2 2.1 2 0 0 2 2 2 2 Alpha galactosidase A Melibiase_C PF17801.1 KIY68157.1 - 8.3e-09 35.4 1.4 9.5e-09 35.2 0.1 1.8 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Glyco_hydro_97 PF10566.9 KIY68157.1 - 0.0041 16.4 0.0 0.019 14.2 0.0 1.9 1 1 0 1 1 1 1 Glycoside hydrolase 97 F-box-like PF12937.7 KIY68159.1 - 6.6e-06 25.9 0.2 1.6e-05 24.7 0.2 1.7 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KIY68159.1 - 0.51 10.8 7.9 2.3 8.8 0.8 3.8 2 2 2 4 4 4 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KIY68160.1 - 2.2e-06 27.5 0.1 6e-06 26.1 0.1 1.8 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KIY68160.1 - 0.0056 17.1 2.6 1.1 9.7 2.4 3.9 3 1 2 5 5 5 3 Leucine Rich repeats (2 copies) DUF4154 PF13689.6 KIY68160.1 - 0.068 13.4 0.0 0.96 9.7 0.0 2.2 2 0 0 2 2 2 0 YfiR/HmsC-like LRR_2 PF07723.13 KIY68160.1 - 0.24 12.1 8.0 0.75 10.6 0.1 3.8 4 0 0 4 4 4 0 Leucine Rich Repeat Mito_carr PF00153.27 KIY68161.1 - 2.4e-60 200.4 0.8 6.3e-22 77.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein F-box-like PF12937.7 KIY68163.1 - 2.2e-06 27.5 0.0 1.1e-05 25.3 0.0 2.2 2 0 0 2 2 2 1 F-box-like CAP59_mtransfer PF11735.8 KIY68164.1 - 8.3e-37 127.2 0.0 1.4e-36 126.5 0.0 1.3 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 CD225 PF04505.12 KIY68165.1 - 0.035 14.2 0.8 12 6.1 0.0 2.8 2 0 0 2 2 2 0 Interferon-induced transmembrane protein ATPase_gene1 PF09527.10 KIY68165.1 - 0.22 11.7 5.5 0.18 12.0 3.4 1.9 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter DUF3817 PF12823.7 KIY68165.1 - 1.6 9.6 11.9 0.58 11.0 1.2 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF3817) DUF996 PF06195.13 KIY68165.1 - 3.8 7.8 9.3 0.33 11.2 2.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF996) ELO PF01151.18 KIY68166.1 - 0.0079 15.8 0.2 0.0079 15.8 0.2 2.1 2 1 0 2 2 2 1 GNS1/SUR4 family SCFA_trans PF02667.14 KIY68166.1 - 0.023 13.7 1.8 0.16 10.9 0.9 2.0 2 0 0 2 2 2 0 Short chain fatty acid transporter DUF92 PF01940.16 KIY68167.1 - 1.2e-75 253.9 9.0 1.4e-75 253.7 9.0 1.0 1 0 0 1 1 1 1 Integral membrane protein DUF92 F-box-like PF12937.7 KIY68168.1 - 2.7e-07 30.4 0.1 1e-06 28.5 0.0 2.0 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 KIY68169.1 - 2.9e-05 23.9 0.1 6.6e-05 22.7 0.1 1.6 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KIY68169.1 - 2.9 8.4 7.1 3.5 8.2 0.2 4.0 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) LRR_4 PF12799.7 KIY68170.1 - 1.9e-36 123.5 7.4 2.6e-08 34.0 0.0 7.0 2 1 2 6 6 6 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KIY68170.1 - 9.2e-31 105.4 2.0 5.3e-09 35.7 0.2 5.1 4 1 0 4 4 4 4 Leucine rich repeat LRR_9 PF14580.6 KIY68170.1 - 1.3e-18 67.1 1.4 1.8e-07 30.8 0.6 4.0 1 1 2 4 4 4 3 Leucine-rich repeat LRR_6 PF13516.6 KIY68170.1 - 1.4e-10 40.4 0.6 0.56 10.4 0.0 6.8 9 0 0 9 9 9 4 Leucine Rich repeat LRR_1 PF00560.33 KIY68170.1 - 2.1e-10 39.7 5.9 3.7 8.5 0.0 9.5 11 0 0 11 11 11 1 Leucine Rich Repeat FNIP PF05725.12 KIY68170.1 - 0.022 14.9 7.7 0.13 12.5 0.9 3.7 3 2 0 3 3 3 0 FNIP Repeat UDPGT PF00201.18 KIY68171.1 - 2.8e-19 69.3 0.0 3.9e-19 68.8 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_trans_1_3 PF13528.6 KIY68171.1 - 0.14 11.4 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 DUF1918 PF08940.11 KIY68172.1 - 0.56 9.9 6.8 0.074 12.7 1.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1918) F-box-like PF12937.7 KIY68173.1 - 2.1e-05 24.3 0.7 8.7e-05 22.3 0.7 2.0 2 0 0 2 2 2 1 F-box-like BAALC_N PF06989.12 KIY68173.1 - 0.11 12.9 0.5 0.24 11.8 0.5 1.5 1 0 0 1 1 1 0 BAALC N-terminus HLH PF00010.26 KIY68174.1 - 2.8e-06 27.2 0.1 6.2e-06 26.1 0.1 1.7 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Rab_bind PF16704.5 KIY68174.1 - 0.011 15.8 0.1 0.05 13.6 0.0 2.1 2 0 0 2 2 2 0 Rab binding domain F-box-like PF12937.7 KIY68175.1 - 0.00016 21.5 0.1 0.00063 19.6 0.0 2.1 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 KIY68176.1 - 0.00036 20.4 0.0 0.0012 18.6 0.0 2.0 1 0 0 1 1 1 1 F-box-like Glycogen_syn PF05693.13 KIY68177.1 - 0 1105.6 0.0 0 1105.4 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.20 KIY68177.1 - 1.4e-06 27.9 0.0 0.00048 19.7 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 KIY68177.1 - 1.9e-06 27.7 0.3 4.4e-06 26.6 0.3 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_1_4 PF13692.6 KIY68177.1 - 6.3e-06 26.7 0.0 0.0043 17.5 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KIY68177.1 - 2.6e-05 24.3 1.0 4.6e-05 23.5 1.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 KIY68177.1 - 8.7e-05 23.0 0.1 0.00022 21.7 0.1 1.7 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain UDPGT PF00201.18 KIY68178.1 - 9.1e-20 70.9 0.0 1.5e-19 70.2 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase UDPGT PF00201.18 KIY68179.1 - 5.8e-19 68.2 0.0 8.4e-19 67.7 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_trans_1_3 PF13528.6 KIY68179.1 - 0.18 11.0 0.0 0.26 10.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 1 Proteasome PF00227.26 KIY68180.1 - 2.7e-28 98.7 0.1 3.3e-28 98.5 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Peptidase_C14 PF00656.22 KIY68181.1 - 5.4e-29 101.9 0.0 8.2e-29 101.3 0.0 1.2 1 0 0 1 1 1 1 Caspase domain SUZ PF12752.7 KIY68181.1 - 4.3 8.2 10.5 2.7 8.8 5.0 2.8 2 0 0 2 2 2 0 SUZ domain CarD_CdnL_TRCF PF02559.16 KIY68182.1 - 0.084 13.6 0.0 0.15 12.8 0.0 1.4 1 0 0 1 1 1 0 CarD-like/TRCF domain STE PF02200.16 KIY68183.1 - 1.4e-53 179.9 0.0 2.3e-53 179.3 0.0 1.3 1 0 0 1 1 1 1 STE like transcription factor zf-C2H2 PF00096.26 KIY68183.1 - 2.2e-10 40.4 13.8 2.7e-06 27.5 1.1 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIY68183.1 - 1.7e-07 31.5 9.9 0.00064 20.3 0.3 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KIY68183.1 - 0.00011 22.5 11.0 0.0011 19.3 2.8 3.7 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_8 PF15909.5 KIY68183.1 - 0.0027 18.0 0.4 0.0061 16.8 0.4 1.5 1 0 0 1 1 1 1 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 KIY68183.1 - 0.015 15.6 3.9 2.2 8.7 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KIY68183.1 - 0.03 14.3 0.2 0.03 14.3 0.2 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2HE PF16278.5 KIY68183.1 - 0.051 14.0 6.0 3.7 8.1 1.8 2.5 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-H2C2_5 PF13909.6 KIY68183.1 - 0.41 10.4 7.3 3.3 7.6 0.1 2.9 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2HC_2 PF13913.6 KIY68183.1 - 2.4 8.2 5.4 0.3 11.0 0.4 2.0 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Redoxin PF08534.10 KIY68185.1 - 7.7e-28 97.1 0.0 9.5e-28 96.8 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KIY68185.1 - 7.2e-12 45.3 0.0 9.3e-12 45.0 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Peptidase_C14 PF00656.22 KIY68186.1 - 6.9e-33 114.6 0.0 1e-32 114.1 0.0 1.2 1 0 0 1 1 1 1 Caspase domain Goodbye PF17109.5 KIY68187.1 - 8.3e-06 26.2 0.0 1.5e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 fungal STAND N-terminal Goodbye domain CNOT1_CAF1_bind PF16415.5 KIY68187.1 - 0.0015 18.0 0.1 0.0022 17.4 0.1 1.2 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain RNA_pol_Rpb2_2 PF04561.14 KIY68187.1 - 0.018 14.7 0.0 0.026 14.1 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 2 TANGO2 PF05742.12 KIY68189.1 - 1.1e-48 166.5 0.0 3.4e-48 164.9 0.0 1.7 1 1 0 1 1 1 1 Transport and Golgi organisation 2 Cas_Csx9 PF09658.10 KIY68189.1 - 0.12 11.5 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csx9) LPMO_10 PF03067.15 KIY68190.1 - 4.6e-11 43.7 0.3 6.2e-11 43.3 0.3 1.2 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading DnaJ-X PF14308.6 KIY68191.1 - 5.3e-44 150.2 10.6 1e-43 149.3 0.2 2.9 2 1 1 3 3 3 2 X-domain of DnaJ-containing DnaJ PF00226.31 KIY68191.1 - 1.6e-24 85.8 1.2 5.9e-24 84.0 0.2 2.3 2 0 0 2 2 2 1 DnaJ domain HscB_4_cys PF18256.1 KIY68191.1 - 0.047 13.5 0.4 0.12 12.2 0.4 1.6 1 0 0 1 1 1 0 Co-chaperone HscB tetracysteine metal binding motif CagY_M PF07337.11 KIY68191.1 - 3.6 7.3 7.2 4.6 7.0 0.3 2.5 2 0 0 2 2 2 0 DC-EC Repeat CBF PF03914.17 KIY68192.1 - 9.6e-42 142.9 4.8 7.6e-41 140.0 0.0 3.1 3 0 0 3 3 3 1 CBF/Mak21 family Cnd1 PF12717.7 KIY68192.1 - 0.00085 19.4 0.1 0.0021 18.1 0.1 1.6 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 KIY68192.1 - 0.015 13.8 0.1 0.03 12.9 0.1 1.4 1 0 0 1 1 1 0 Adaptin N terminal region RTP1_C1 PF10363.9 KIY68192.1 - 0.051 13.8 0.1 0.13 12.5 0.1 1.7 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 1 R_equi_Vir PF05526.11 KIY68192.1 - 0.11 12.3 0.0 0.31 10.9 0.0 1.7 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein Pkinase PF00069.25 KIY68193.1 - 5.6e-06 25.9 0.0 8.2e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY68193.1 - 0.13 11.6 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.25 KIY68194.1 - 4.2e-05 23.0 0.0 6.9e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.25 KIY68195.1 - 0.00024 20.6 0.0 0.00034 20.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Gag_p24 PF00607.20 KIY68195.1 - 0.17 11.8 0.1 0.25 11.2 0.1 1.2 1 0 0 1 1 1 0 gag gene protein p24 (core nucleocapsid protein) Alpha_L_fucos PF01120.17 KIY68196.1 - 1.9e-34 119.6 0.0 1.2e-33 117.0 0.0 2.0 1 1 0 1 1 1 1 Alpha-L-fucosidase F5_F8_type_C PF00754.25 KIY68196.1 - 5.2e-05 23.4 0.0 0.00013 22.0 0.0 1.6 1 0 0 1 1 1 1 F5/8 type C domain Amidase PF01425.21 KIY68198.1 - 5.2e-57 193.8 2.8 6.4e-57 193.5 2.8 1.0 1 0 0 1 1 1 1 Amidase JHD PF17811.1 KIY68200.1 - 1.7e-09 38.1 0.0 3.7e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Jumonji helical domain PHD PF00628.29 KIY68200.1 - 2e-07 30.8 7.8 3.3e-07 30.1 7.8 1.4 1 0 0 1 1 1 1 PHD-finger JmjC PF02373.22 KIY68200.1 - 2.3e-07 31.3 1.0 4.5e-06 27.1 1.0 2.4 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 KIY68200.1 - 0.0035 17.1 0.1 0.071 12.8 0.1 2.3 1 1 0 1 1 1 1 Cupin-like domain Prok-RING_1 PF14446.6 KIY68200.1 - 0.0062 16.4 3.9 0.011 15.6 3.9 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 PHD_2 PF13831.6 KIY68200.1 - 0.039 13.5 5.0 0.075 12.6 5.0 1.4 1 0 0 1 1 1 0 PHD-finger GPI PF06560.11 KIY68200.1 - 0.16 11.3 0.0 0.31 10.3 0.0 1.4 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) zf-HC5HC2H PF13771.6 KIY68200.1 - 0.34 11.2 1.5 0.71 10.2 1.5 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain C1_1 PF00130.22 KIY68200.1 - 0.43 10.5 4.5 0.96 9.4 4.5 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 KIY68200.1 - 5 7.5 5.2 0.94 9.8 1.3 1.7 2 0 0 2 2 2 0 C1 domain Cu-oxidase_3 PF07732.15 KIY68202.1 - 1.6e-27 95.9 1.8 2.8e-26 91.9 0.2 2.6 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KIY68202.1 - 7.8e-27 93.7 2.5 3.7e-21 75.3 0.0 3.7 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 KIY68202.1 - 6.2e-13 49.2 0.0 5.3e-10 39.6 0.0 2.5 2 1 0 2 2 2 2 Multicopper oxidase Helicase_C PF00271.31 KIY68203.1 - 2.7e-15 56.7 0.0 8.7e-15 55.0 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HA2 PF04408.23 KIY68203.1 - 2.3e-13 50.4 0.0 5.2e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KIY68203.1 - 2.5e-09 37.4 0.0 6.4e-09 36.1 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 KIY68203.1 - 3.8e-06 26.8 0.0 1.3e-05 25.1 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KIY68203.1 - 0.001 19.4 0.1 0.0037 17.5 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KIY68203.1 - 0.0019 17.9 0.0 0.0034 17.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KIY68203.1 - 0.039 14.3 0.0 0.077 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 KIY68203.1 - 0.13 11.2 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein USP7_ICP0_bdg PF12436.8 KIY68203.1 - 0.22 10.8 0.0 0.36 10.1 0.0 1.3 1 0 0 1 1 1 0 ICP0-binding domain of Ubiquitin-specific protease 7 AAA_23 PF13476.6 KIY68203.1 - 0.25 11.8 0.0 0.47 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF572 PF04502.13 KIY68204.1 - 1.3e-80 271.5 8.9 1.5e-80 271.4 8.9 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) zf-FCS PF06467.14 KIY68204.1 - 0.015 15.2 1.0 0.54 10.2 0.1 2.3 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif DUF866 PF05907.13 KIY68204.1 - 0.046 13.6 0.8 0.087 12.7 0.8 1.5 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) Tetraspanin PF00335.20 KIY68206.1 - 1.3e-06 28.3 14.3 3.4e-06 26.9 14.3 1.7 1 1 0 1 1 1 1 Tetraspanin family DUF485 PF04341.12 KIY68206.1 - 1.1 9.2 6.0 0.64 10.0 2.4 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF485 Cpn60_TCP1 PF00118.24 KIY68207.1 - 6.2e-144 480.3 13.0 7.1e-144 480.1 13.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF5442 PF17514.2 KIY68207.1 - 0.03 14.5 0.1 0.073 13.3 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5442) CRM1_repeat PF18777.1 KIY68207.1 - 0.068 12.7 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat PMT PF02366.18 KIY68208.1 - 1.4e-80 270.4 16.9 2.9e-80 269.4 16.9 1.6 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KIY68208.1 - 5e-67 225.4 13.4 5e-67 225.4 13.4 2.2 3 0 0 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KIY68208.1 - 9.1e-40 136.5 0.0 1.8e-39 135.5 0.0 1.4 1 0 0 1 1 1 1 MIR domain PMT_2 PF13231.6 KIY68208.1 - 0.00084 19.6 11.2 0.00084 19.6 11.2 2.9 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase DUF1435 PF07256.12 KIY68208.1 - 0.081 13.0 3.0 6.4 7.0 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1435) SbcCD_C PF13558.6 KIY68208.1 - 0.12 12.6 0.0 0.29 11.4 0.0 1.6 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit DUF1240 PF06836.12 KIY68208.1 - 0.27 11.8 3.6 27 5.4 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF1240) Ifi-6-16 PF06140.13 KIY68209.1 - 7.1e-07 29.1 4.2 1.5e-06 28.0 4.2 1.5 1 0 0 1 1 1 1 Interferon-induced 6-16 family Acetate_kinase PF00871.17 KIY68209.1 - 0.014 14.1 0.1 0.018 13.7 0.1 1.1 1 0 0 1 1 1 0 Acetokinase family RRM_1 PF00076.22 KIY68211.1 - 4.8e-12 45.5 0.0 5.4e-12 45.4 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KIY68211.1 - 6.8e-07 28.9 0.0 8.2e-07 28.7 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KIY68211.1 - 0.001 18.9 0.2 0.0017 18.1 0.2 1.4 1 1 0 1 1 1 1 Occluded RNA-recognition motif Limkain-b1 PF11608.8 KIY68211.1 - 0.028 14.5 0.1 0.036 14.1 0.1 1.4 1 1 0 1 1 1 0 Limkain b1 Nup35_RRM_2 PF14605.6 KIY68211.1 - 0.029 14.4 0.0 0.052 13.6 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RNase_PH PF01138.21 KIY68212.1 - 2.7e-18 66.8 0.0 5e-18 65.9 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 DUF1749 PF08538.10 KIY68213.1 - 0.047 12.8 0.0 0.084 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Abhydrolase_5 PF12695.7 KIY68213.1 - 0.086 12.6 0.0 0.4 10.4 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 KIY68213.1 - 0.17 10.8 0.0 0.32 9.9 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme zf-MYND PF01753.18 KIY68214.1 - 4e-08 33.2 10.6 7.4e-08 32.4 10.6 1.4 1 0 0 1 1 1 1 MYND finger Ifi-6-16 PF06140.13 KIY68215.1 - 1.2e-06 28.3 4.7 2.8e-06 27.1 4.7 1.6 1 0 0 1 1 1 1 Interferon-induced 6-16 family DUF3726 PF12525.8 KIY68215.1 - 0.044 13.9 1.1 0.22 11.6 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3726) LcrR PF09621.10 KIY68217.1 - 0.042 13.3 0.0 0.061 12.8 0.0 1.3 1 0 0 1 1 1 0 Type III secretion system regulator (LcrR) COesterase PF00135.28 KIY68218.1 - 1.6e-13 50.4 0.0 2.3e-09 36.7 0.0 2.3 1 1 1 2 2 2 2 Carboxylesterase family DASH_Duo1 PF08651.10 KIY68219.1 - 0.018 14.8 0.2 0.087 12.6 0.1 2.1 1 1 1 2 2 2 0 DASH complex subunit Duo1 p450 PF00067.22 KIY68220.1 - 1.5e-34 119.6 0.2 1.3e-33 116.5 0.1 2.0 1 1 1 2 2 2 2 Cytochrome P450 zf-C4H2 PF10146.9 KIY68221.1 - 0.15 12.3 0.0 0.32 11.3 0.0 1.6 2 0 0 2 2 2 0 Zinc finger-containing protein Myb_DNA-binding PF00249.31 KIY68224.1 - 6.9e-37 125.4 6.6 3.7e-13 49.4 1.0 3.1 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KIY68224.1 - 5.3e-25 87.4 1.1 1.6e-12 47.4 0.1 3.1 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_2 PF08914.11 KIY68224.1 - 0.00041 20.5 0.1 1.3 9.3 0.0 3.1 3 0 0 3 3 3 2 Rap1 Myb domain SLIDE PF09111.10 KIY68224.1 - 0.0063 16.5 0.0 1.8 8.6 0.0 2.8 1 1 2 3 3 3 1 SLIDE MADF_DNA_bdg PF10545.9 KIY68224.1 - 0.023 15.0 1.5 3.6 8.0 0.1 3.0 3 0 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_7 PF15963.5 KIY68224.1 - 0.025 14.5 0.0 1.8 8.5 0.0 2.8 2 1 1 3 3 3 0 Myb DNA-binding like SANT_DAMP1_like PF16282.5 KIY68224.1 - 0.052 13.8 0.4 1.3 9.3 0.0 2.6 2 1 1 3 3 3 0 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_4 PF13837.6 KIY68224.1 - 0.064 13.6 8.8 0.9 10.0 1.5 3.4 3 1 0 3 3 3 0 Myb/SANT-like DNA-binding domain HMG_box PF00505.19 KIY68227.1 - 1.1e-12 48.1 2.2 2.5e-12 47.0 2.2 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KIY68227.1 - 7.3e-05 23.3 1.5 0.00017 22.1 1.5 1.6 1 0 0 1 1 1 1 HMG-box domain GST_N PF02798.20 KIY68228.1 - 1.7e-17 63.5 0.0 1.2e-16 60.7 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KIY68228.1 - 8e-15 54.8 0.2 1.6e-14 53.8 0.1 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KIY68228.1 - 1e-12 48.2 0.0 2.8e-12 46.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KIY68228.1 - 6.3e-10 39.2 0.0 1.2e-09 38.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KIY68228.1 - 3.8e-07 30.2 0.0 6.6e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KIY68228.1 - 2e-06 27.7 0.0 3.4e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain p450 PF00067.22 KIY68230.1 - 8.8e-54 183.0 0.0 1.1e-53 182.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 zf-C2H2 PF00096.26 KIY68231.1 - 4.6e-10 39.4 14.2 6e-05 23.3 1.5 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KIY68231.1 - 0.00011 22.2 7.5 0.046 13.7 0.9 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_4 PF13894.6 KIY68231.1 - 0.00011 22.7 13.0 0.03 15.2 1.1 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KIY68231.1 - 0.0011 19.3 14.2 0.13 12.7 1.2 4.5 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_11 PF16622.5 KIY68231.1 - 0.019 14.7 1.1 0.019 14.7 1.1 1.8 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 KIY68231.1 - 0.22 11.8 5.7 3 8.3 0.4 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 KIY68231.1 - 0.42 10.9 6.7 0.4 11.0 0.3 2.8 2 1 1 3 3 3 0 C2H2-type zinc ribbon zf-met PF12874.7 KIY68231.1 - 1 9.8 6.5 1.2 9.6 0.4 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2HE PF16278.5 KIY68231.1 - 5.1 7.6 6.2 1.1 9.8 0.4 2.4 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger AMP-binding PF00501.28 KIY68232.1 - 2.6e-87 293.2 0.0 3.3e-87 292.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KIY68232.1 - 4e-15 56.6 2.0 4.3e-15 56.5 0.6 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Lactonase PF10282.9 KIY68236.1 - 3.1e-37 128.6 0.3 3.7e-37 128.4 0.3 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller XRN1_D1 PF18332.1 KIY68238.1 - 9e-41 139.8 0.0 1.4e-40 139.1 0.0 1.2 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D1 domain SH3_12 PF18129.1 KIY68238.1 - 2.9e-22 78.5 0.8 8.3e-22 77.1 0.8 1.8 1 0 0 1 1 1 1 Xrn1 SH3-like domain XRN1_D2_D3 PF18334.1 KIY68238.1 - 6.3e-11 42.3 0.0 2.1e-10 40.7 0.0 1.9 2 0 0 2 2 2 1 Exoribonuclease Xrn1 D2/D3 domain PSII_Pbs27 PF13326.6 KIY68239.1 - 0.11 12.8 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 Photosystem II Pbs27 Ecl1 PF12855.7 KIY68241.1 - 9.2 7.4 13.9 13 7.0 13.9 1.1 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins zf-MYND PF01753.18 KIY68242.1 - 0.00025 21.1 14.9 0.00025 21.1 14.9 2.1 2 0 0 2 2 2 1 MYND finger DUF5561 PF17716.1 KIY68242.1 - 0.26 10.5 0.0 0.26 10.5 0.0 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5561) zf-MYND PF01753.18 KIY68243.1 - 0.00086 19.3 18.1 0.00086 19.3 18.1 1.8 2 0 0 2 2 2 1 MYND finger zf-MYND PF01753.18 KIY68244.1 - 0.00064 19.8 17.0 0.0015 18.6 17.0 1.6 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KIY68244.1 - 0.24 11.8 9.8 0.5 10.7 9.8 1.5 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 KIY68245.1 - 8.5e-06 25.8 17.8 1.6e-05 24.9 17.8 1.5 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KIY68245.1 - 0.29 11.5 8.1 0.6 10.5 8.1 1.5 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding YesK PF14150.6 KIY68246.1 - 2.3 8.4 7.9 0.81 9.9 1.0 3.0 2 1 1 3 3 3 0 YesK-like protein p450 PF00067.22 KIY68248.1 - 8.3e-16 57.8 0.0 1.1e-15 57.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Retrotran_gag_2 PF14223.6 KIY68249.1 - 5e-17 61.8 0.1 8.1e-17 61.2 0.1 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type rve PF00665.26 KIY68249.1 - 3.4e-14 53.0 0.0 1.3e-13 51.1 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.6 KIY68249.1 - 7.8e-13 48.1 1.5 1.6e-12 47.1 0.0 2.2 2 0 0 2 2 2 1 GAG-pre-integrase domain RVT_2 PF07727.14 KIY68249.1 - 1.3e-05 25.0 0.0 2.2e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 KIY68249.1 - 0.00054 20.2 1.1 0.0014 18.9 0.1 2.2 2 0 0 2 2 2 1 Retrotransposon gag protein rve_3 PF13683.6 KIY68249.1 - 0.0016 18.2 0.0 0.0058 16.4 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain zf-CCHC PF00098.23 KIY68249.1 - 0.03 14.4 1.1 0.067 13.3 1.1 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-C2H2_10 PF16588.5 KIY68249.1 - 0.2 11.4 0.5 0.37 10.6 0.5 1.5 1 0 0 1 1 1 0 C2H2 zinc-finger p450 PF00067.22 KIY68250.1 - 1.4e-38 132.9 0.0 2.3e-38 132.1 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 DUF382 PF04037.13 KIY68251.1 - 3.5e-56 188.8 0.2 3.5e-56 188.8 0.2 2.8 2 1 1 3 3 3 1 Domain of unknown function (DUF382) PSP PF04046.16 KIY68251.1 - 3.7e-17 61.9 4.8 8e-17 60.8 4.8 1.6 1 0 0 1 1 1 1 PSP UPRTase PF14681.6 KIY68252.1 - 3.5e-37 127.9 0.1 7.9e-37 126.7 0.1 1.6 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase HAD PF12710.7 KIY68252.1 - 2e-17 64.2 0.0 4.7e-17 63.0 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase AAA_17 PF13207.6 KIY68252.1 - 1.6e-11 44.7 0.0 5e-11 43.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain Hydrolase PF00702.26 KIY68252.1 - 7.3e-05 23.1 0.0 0.00011 22.5 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Pribosyltran PF00156.27 KIY68252.1 - 0.00015 21.3 1.0 0.00058 19.4 0.2 2.3 2 1 0 2 2 2 1 Phosphoribosyl transferase domain RNA_Me_trans PF04252.13 KIY68252.1 - 0.0003 20.4 0.0 0.00052 19.6 0.0 1.3 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase ATPase_2 PF01637.18 KIY68252.1 - 0.0022 17.9 0.0 0.0044 17.0 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Peptidase_U4 PF03419.13 KIY68252.1 - 0.0073 15.6 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 Sporulation factor SpoIIGA ABC_tran PF00005.27 KIY68252.1 - 0.0096 16.4 0.0 0.023 15.2 0.0 1.6 1 0 0 1 1 1 1 ABC transporter KAP_NTPase PF07693.14 KIY68252.1 - 0.015 14.5 0.0 0.027 13.7 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain AAA_16 PF13191.6 KIY68252.1 - 0.032 14.6 0.0 0.14 12.5 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain RsgA_GTPase PF03193.16 KIY68252.1 - 0.056 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase Virul_Fac PF10139.9 KIY68252.1 - 0.087 11.0 0.0 0.13 10.4 0.0 1.1 1 0 0 1 1 1 0 Putative bacterial virulence factor PRTase_2 PF15609.6 KIY68252.1 - 0.12 11.9 0.1 0.52 9.8 0.1 2.0 2 0 0 2 2 2 0 Phosphoribosyl transferase AAA_14 PF13173.6 KIY68252.1 - 0.18 11.9 0.0 0.49 10.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain Glyco_hydro_88 PF07470.13 KIY68255.1 - 1.6e-16 60.4 0.2 2.5e-16 59.7 0.2 1.3 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 EMP24_GP25L PF01105.24 KIY68256.1 - 1e-43 149.4 0.0 1.2e-43 149.2 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF2569 PF10754.9 KIY68256.1 - 0.0094 16.4 0.2 0.016 15.7 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2569) F-box-like PF12937.7 KIY68257.1 - 5.6e-06 26.2 0.8 1.7e-05 24.6 0.2 2.1 2 0 0 2 2 2 1 F-box-like MHYT PF03707.16 KIY68258.1 - 0.5 10.6 3.1 3.8 7.8 0.1 2.3 2 0 0 2 2 2 0 Bacterial signalling protein N terminal repeat zf-C2H2 PF00096.26 KIY68259.1 - 4.7e-09 36.2 12.0 0.0002 21.6 2.6 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KIY68259.1 - 1.4e-06 28.5 2.5 1.4e-06 28.5 2.5 4.1 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_8 PF15909.5 KIY68259.1 - 0.00037 20.8 0.4 0.00037 20.8 0.4 1.7 2 0 0 2 2 2 1 C2H2-type zinc ribbon zf-C2H2_4 PF13894.6 KIY68259.1 - 0.038 14.8 1.5 0.038 14.8 1.5 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger ARS2 PF04959.13 KIY68259.1 - 0.12 12.7 3.1 0.057 13.8 0.6 1.7 1 1 1 2 2 2 0 Arsenite-resistance protein 2 zf-C2H2_aberr PF17017.5 KIY68259.1 - 4.4 7.4 5.7 19 5.3 5.7 1.8 1 1 1 2 2 2 0 Aberrant zinc-finger zf-H2C2_5 PF13909.6 KIY68259.1 - 9 6.2 11.0 5.1 6.9 1.7 2.7 2 0 0 2 2 2 0 C2H2-type zinc-finger domain OB_NTP_bind PF07717.16 KIY68260.1 - 2.2e-22 79.2 0.0 9.7e-22 77.1 0.0 2.2 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 KIY68260.1 - 1.2e-21 77.0 0.0 1.2e-21 77.0 0.0 1.9 2 0 0 2 2 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KIY68260.1 - 2.4e-10 40.7 0.0 1.2e-09 38.5 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KIY68260.1 - 1.5e-07 31.3 0.9 3e-07 30.4 0.9 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase SRP54 PF00448.22 KIY68260.1 - 0.0002 21.0 0.9 0.00087 19.0 0.9 1.9 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_22 PF13401.6 KIY68260.1 - 0.00082 19.7 0.0 0.0029 17.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KIY68260.1 - 0.0013 19.1 0.3 0.0025 18.2 0.3 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KIY68260.1 - 0.0075 16.0 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KIY68260.1 - 0.011 14.8 0.0 0.027 13.5 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein PTPlike_phytase PF14566.6 KIY68260.1 - 0.017 15.3 0.0 0.034 14.3 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate AAA_7 PF12775.7 KIY68260.1 - 0.017 14.6 1.9 0.15 11.6 0.0 2.8 3 0 0 3 3 3 0 P-loop containing dynein motor region DUF2075 PF09848.9 KIY68260.1 - 0.024 13.9 0.0 0.048 12.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Flavi_DEAD PF07652.14 KIY68260.1 - 0.031 14.3 0.3 0.074 13.0 0.3 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain ATPase PF06745.13 KIY68260.1 - 0.04 13.3 0.0 0.086 12.2 0.0 1.5 1 0 0 1 1 1 0 KaiC PhoH PF02562.16 KIY68260.1 - 0.045 13.2 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein ABC_tran PF00005.27 KIY68260.1 - 0.08 13.5 0.0 0.19 12.3 0.0 1.6 1 0 0 1 1 1 0 ABC transporter ResIII PF04851.15 KIY68260.1 - 0.15 12.1 0.2 2.5 8.1 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit ATPase_2 PF01637.18 KIY68260.1 - 0.15 11.9 0.0 0.32 10.9 0.0 1.5 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea HA2 PF04408.23 KIY68261.1 - 3.8e-20 72.2 0.0 6.9e-20 71.3 0.0 1.4 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KIY68261.1 - 2.4e-18 66.2 0.0 8.1e-18 64.6 0.0 1.9 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold SRP54 PF00448.22 KIY68261.1 - 0.00034 20.3 0.3 0.002 17.8 0.1 2.3 2 1 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_22 PF13401.6 KIY68261.1 - 0.00039 20.7 0.0 0.00098 19.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 KIY68261.1 - 0.0097 15.7 0.6 0.021 14.6 0.1 1.8 2 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_19 PF13245.6 KIY68261.1 - 0.01 16.2 0.0 0.02 15.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KIY68261.1 - 0.012 14.8 0.0 0.024 13.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.27 KIY68261.1 - 0.015 15.9 0.0 0.03 14.8 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_30 PF13604.6 KIY68261.1 - 0.027 14.2 0.0 0.048 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 KIY68261.1 - 0.039 13.0 0.4 0.08 12.0 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_7 PF12775.7 KIY68261.1 - 0.063 12.8 0.1 0.14 11.7 0.1 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase PF06745.13 KIY68261.1 - 0.075 12.4 0.1 0.24 10.7 0.0 1.8 2 0 0 2 2 2 0 KaiC Septin PF00735.18 KIY68262.1 - 3.2e-112 374.4 0.4 4.8e-112 373.8 0.4 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KIY68262.1 - 8e-08 32.4 0.1 2.4e-07 30.8 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIY68262.1 - 2.8e-06 27.3 0.3 3.1e-05 23.9 0.2 2.5 2 1 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 KIY68262.1 - 2.8e-06 27.0 1.9 0.00039 20.0 0.0 2.8 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain Roc PF08477.13 KIY68262.1 - 0.00021 21.5 0.0 0.00047 20.4 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 KIY68262.1 - 0.0011 19.4 0.4 0.0054 17.1 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KIY68262.1 - 0.0012 19.1 1.8 0.0048 17.2 0.1 2.6 2 1 1 3 3 3 1 AAA domain PduV-EutP PF10662.9 KIY68262.1 - 0.0032 17.2 0.3 0.15 11.8 0.1 2.5 1 1 1 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AIG1 PF04548.16 KIY68262.1 - 0.0037 16.6 0.0 0.0095 15.3 0.0 1.7 1 0 0 1 1 1 1 AIG1 family ABC_tran PF00005.27 KIY68262.1 - 0.0043 17.6 0.1 0.012 16.1 0.0 1.8 2 0 0 2 2 2 1 ABC transporter AAA_7 PF12775.7 KIY68262.1 - 0.0097 15.4 0.1 0.018 14.5 0.1 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region Ras PF00071.22 KIY68262.1 - 0.012 15.2 0.1 0.039 13.6 0.1 1.9 1 1 0 1 1 1 0 Ras family Casc1_N PF15927.5 KIY68262.1 - 0.018 14.8 6.5 0.058 13.1 6.5 1.8 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus AAA_24 PF13479.6 KIY68262.1 - 0.03 14.0 0.2 0.08 12.7 0.2 1.8 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KIY68262.1 - 0.04 13.1 0.0 0.063 12.5 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain NACHT PF05729.12 KIY68262.1 - 0.063 13.2 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.6 KIY68262.1 - 0.075 13.1 0.5 0.15 12.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 KIY68262.1 - 0.082 13.0 6.7 1.2 9.2 0.1 3.1 2 1 1 3 3 3 0 Dynamin family AAA_25 PF13481.6 KIY68262.1 - 0.12 11.9 0.9 0.33 10.5 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KIY68262.1 - 0.14 11.9 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain FeoB_N PF02421.18 KIY68262.1 - 0.19 11.3 0.2 0.79 9.2 0.2 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B Bac_DnaA PF00308.18 KIY68262.1 - 0.4 10.5 4.2 3.9 7.2 0.7 2.8 2 1 0 2 2 2 0 Bacterial dnaA protein SAS4 PF15460.6 KIY68262.1 - 8.1 6.6 13.8 2.4 8.3 1.1 3.3 2 2 1 3 3 3 0 Something about silencing, SAS, complex subunit 4 S36_mt PF10937.8 KIY68265.1 - 4.8e-07 31.4 0.3 0.0055 18.3 0.5 2.3 1 1 1 2 2 2 2 Ribosomal protein S36, mitochondrial S36_mt PF10937.8 KIY68266.1 - 2.2e-06 29.2 6.9 0.0068 18.0 0.1 3.9 2 2 2 4 4 4 2 Ribosomal protein S36, mitochondrial PAGK PF15284.6 KIY68266.1 - 0.18 11.7 8.6 2 8.4 0.3 3.5 3 1 0 3 3 3 0 Phage-encoded virulence factor Lipase_GDSL PF00657.22 KIY68267.1 - 3.5e-09 36.9 0.0 4e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 KIY68267.1 - 0.00018 22.0 0.4 0.00033 21.1 0.4 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Sorb PF02208.16 KIY68267.1 - 0.034 14.0 0.1 0.088 12.7 0.1 1.7 1 0 0 1 1 1 0 Sorbin homologous domain Lipase_GDSL PF00657.22 KIY68268.1 - 2.8e-10 40.5 0.0 4.3e-10 39.9 0.0 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 KIY68268.1 - 0.00051 20.5 1.5 0.00097 19.6 1.5 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family F-box-like PF12937.7 KIY68269.1 - 9.8e-09 35.0 2.5 1.6e-08 34.3 1.1 2.1 2 0 0 2 2 2 1 F-box-like GPS2_interact PF15784.5 KIY68269.1 - 0.046 14.2 0.0 0.092 13.2 0.0 1.4 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain CAMP_factor PF07373.11 KIY68269.1 - 0.11 12.1 0.1 0.24 11.0 0.1 1.5 1 0 0 1 1 1 0 CAMP factor (Cfa) OB_NTP_bind PF07717.16 KIY68270.1 - 1e-22 80.3 0.0 4e-22 78.4 0.0 2.1 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 KIY68270.1 - 2.5e-22 79.2 0.0 2.5e-22 79.2 0.0 2.1 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KIY68270.1 - 5.9e-11 42.7 0.0 2.4e-10 40.7 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KIY68270.1 - 1.7e-07 31.2 0.2 3.5e-07 30.2 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase SRP54 PF00448.22 KIY68270.1 - 2.2e-05 24.2 0.5 0.00012 21.8 0.5 2.0 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_22 PF13401.6 KIY68270.1 - 0.00078 19.7 0.0 0.0025 18.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KIY68270.1 - 0.0013 19.1 0.2 0.0025 18.1 0.2 1.4 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 KIY68270.1 - 0.0043 16.4 0.0 0.0088 15.3 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 KIY68270.1 - 0.0045 16.7 0.0 0.008 15.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain PTPlike_phytase PF14566.6 KIY68270.1 - 0.0084 16.2 0.0 0.017 15.3 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate AAA_7 PF12775.7 KIY68270.1 - 0.01 15.4 0.1 0.2 11.1 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region ResIII PF04851.15 KIY68270.1 - 0.015 15.3 0.1 2.7 8.0 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.14 KIY68270.1 - 0.021 14.8 0.4 0.046 13.7 0.4 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain PhoH PF02562.16 KIY68270.1 - 0.057 12.9 0.0 0.17 11.3 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein T2SSE PF00437.20 KIY68270.1 - 0.057 12.5 0.0 0.1 11.6 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.27 KIY68270.1 - 0.11 13.0 0.0 0.25 11.8 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_14 PF13173.6 KIY68270.1 - 0.13 12.3 0.0 2 8.5 0.0 2.5 1 1 0 1 1 1 0 AAA domain ADH_zinc_N PF00107.26 KIY68271.1 - 3.9e-19 68.9 0.0 6.1e-19 68.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KIY68271.1 - 1.5e-14 53.8 0.0 3.9e-14 52.4 0.0 1.7 2 0 0 2 2 2 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 KIY68271.1 - 2.4e-08 35.1 0.0 4.2e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Aminotran_1_2 PF00155.21 KIY68271.1 - 0.11 11.6 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II TrkA_N PF02254.18 KIY68271.1 - 0.17 12.2 0.0 0.34 11.2 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Mid2 PF04478.12 KIY68272.1 - 1.6e-05 24.8 0.0 3.2e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor SKG6 PF08693.10 KIY68272.1 - 0.00049 19.5 1.4 0.001 18.4 1.4 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain CD34_antigen PF06365.12 KIY68272.1 - 0.046 13.3 0.0 0.085 12.4 0.0 1.4 1 0 0 1 1 1 0 CD34/Podocalyxin family DUF2207 PF09972.9 KIY68272.1 - 0.046 12.5 0.0 0.062 12.1 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) G6B PF15096.6 KIY68272.1 - 0.049 13.4 0.0 0.085 12.6 0.0 1.3 1 0 0 1 1 1 0 G6B family ATP-synt_C PF00137.21 KIY68272.1 - 0.074 13.4 2.0 0.13 12.6 2.0 1.4 1 0 0 1 1 1 0 ATP synthase subunit C NCU-G1 PF15065.6 KIY68272.1 - 0.13 11.3 0.1 0.2 10.6 0.1 1.3 1 0 0 1 1 1 0 Lysosomal transcription factor, NCU-G1 SKG6 PF08693.10 KIY68274.1 - 0.0071 15.7 1.5 0.018 14.4 1.5 1.8 1 0 0 1 1 1 1 Transmembrane alpha-helix domain PTP_tm PF18861.1 KIY68274.1 - 0.034 14.2 0.3 0.063 13.3 0.3 1.4 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Cellulase PF00150.18 KIY68275.1 - 1.2e-31 110.3 0.1 1.9e-31 109.5 0.1 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) NmrA PF05368.13 KIY68276.1 - 8.2e-17 61.5 0.1 1.1e-16 61.2 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KIY68276.1 - 1.1e-06 28.6 0.1 4.7e-05 23.4 0.1 2.1 2 0 0 2 2 2 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KIY68276.1 - 0.00011 22.4 0.1 0.0002 21.6 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 KIY68276.1 - 0.00027 21.5 0.1 0.0054 17.3 0.0 2.5 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.18 KIY68276.1 - 0.00075 19.8 0.1 0.0013 18.9 0.1 1.4 1 0 0 1 1 1 1 TrkA-N domain 3HCDH_N PF02737.18 KIY68276.1 - 0.0012 18.8 0.0 0.0021 18.0 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 KIY68276.1 - 0.0035 17.4 0.0 0.0081 16.2 0.0 1.7 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_2 PF03446.15 KIY68276.1 - 0.0062 16.7 0.0 0.011 15.9 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Epimerase PF01370.21 KIY68276.1 - 0.011 15.2 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 KIY68276.1 - 0.013 14.9 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 KIY68276.1 - 0.026 14.5 0.5 0.053 13.5 0.1 1.7 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Shikimate_DH PF01488.20 KIY68276.1 - 0.036 14.1 0.0 0.063 13.3 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase CHAT PF12770.7 KIY68278.1 - 1.4e-38 133.0 0.2 3.5e-38 131.7 0.1 1.8 2 0 0 2 2 2 1 CHAT domain TPR_10 PF13374.6 KIY68278.1 - 4.3e-17 61.4 15.1 0.0018 18.1 0.0 10.1 12 0 0 12 12 12 4 Tetratricopeptide repeat TPR_8 PF13181.6 KIY68278.1 - 3.9e-12 45.4 2.5 0.12 12.6 0.0 9.2 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_11 PF13414.6 KIY68278.1 - 1.7e-08 34.0 0.4 4.4 7.1 0.0 8.4 9 0 0 9 9 9 1 TPR repeat TPR_2 PF07719.17 KIY68278.1 - 5.2e-08 32.4 6.8 6.2 7.2 0.0 9.2 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_12 PF13424.6 KIY68278.1 - 1.6e-07 31.5 13.3 0.42 10.9 0.0 9.7 10 2 2 12 12 12 3 Tetratricopeptide repeat TPR_1 PF00515.28 KIY68278.1 - 1.1e-06 28.1 5.2 7.2 6.6 0.1 8.3 10 0 0 10 10 10 1 Tetratricopeptide repeat DUF627 PF04781.12 KIY68278.1 - 0.0041 17.1 1.5 30 4.7 0.0 5.6 6 0 0 6 6 6 0 Protein of unknown function (DUF627) Thiol_cytolysin PF01289.19 KIY68278.1 - 0.22 10.4 0.0 0.71 8.7 0.0 1.7 2 0 0 2 2 2 0 Thiol-activated cytolysin TPR_14 PF13428.6 KIY68278.1 - 0.91 10.5 19.7 73 4.6 0.0 9.9 10 1 1 11 11 11 0 Tetratricopeptide repeat Vta1_C PF18097.1 KIY68278.1 - 2.8 7.7 4.9 6.9 6.5 0.1 3.6 3 0 0 3 3 3 0 Vta1 C-terminal domain CENP-T_C PF15511.6 KIY68279.1 - 3.8e-07 30.2 0.0 4.6e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 KIY68279.1 - 2.7e-05 24.3 0.1 3.8e-05 23.8 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 KIY68279.1 - 0.00016 21.9 0.0 0.0002 21.6 0.0 1.3 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KIY68279.1 - 0.00067 19.9 0.1 0.0013 19.0 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KIY68279.1 - 0.00078 19.8 0.2 0.00084 19.7 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KIY68279.1 - 0.048 13.7 0.0 0.054 13.6 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KIY68279.1 - 0.11 12.5 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated SRP9-21 PF05486.12 KIY68281.1 - 3.3e-11 43.4 0.5 1.7e-09 37.9 0.5 2.4 1 1 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) GDPD PF03009.17 KIY68281.1 - 0.063 13.0 0.1 0.07 12.8 0.1 1.0 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family RBR PF17208.3 KIY68282.1 - 4.2 8.1 11.4 1.4 9.7 1.1 2.7 2 1 1 3 3 3 0 RNA binding Region Mid1 PF12929.7 KIY68283.1 - 4.1e-57 194.3 0.1 5.7e-57 193.8 0.1 1.1 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.22 KIY68283.1 - 0.00012 22.7 4.0 0.0051 17.4 0.7 2.6 2 1 0 2 2 2 2 Fz domain Pur_ac_phosph_N PF16656.5 KIY68283.1 - 0.0099 16.4 0.1 0.025 15.1 0.1 1.8 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain CHAT PF12770.7 KIY68286.1 - 1e-35 123.6 0.0 1.9e-35 122.7 0.0 1.4 1 0 0 1 1 1 1 CHAT domain TPR_10 PF13374.6 KIY68286.1 - 4.7e-16 58.1 18.8 5.5e-05 22.9 0.2 10.6 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_12 PF13424.6 KIY68286.1 - 7.1e-07 29.4 14.2 2.2 8.6 0.0 8.5 6 3 4 10 10 9 2 Tetratricopeptide repeat TPR_8 PF13181.6 KIY68286.1 - 0.00096 19.2 0.7 18 5.9 0.0 6.9 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_2 PF07719.17 KIY68286.1 - 0.0049 16.9 3.2 1.7e+02 2.7 0.0 7.5 8 1 0 8 8 8 0 Tetratricopeptide repeat Sel1 PF08238.12 KIY68286.1 - 0.006 17.2 0.1 1.6 9.5 0.0 4.5 4 0 0 4 4 4 1 Sel1 repeat TPR_11 PF13414.6 KIY68286.1 - 0.0075 15.9 0.9 47 3.8 0.0 6.0 7 0 0 7 7 7 0 TPR repeat TPR_MalT PF17874.1 KIY68286.1 - 0.027 13.9 2.0 20 4.4 0.0 3.6 3 1 0 4 4 4 0 MalT-like TPR region CclA_1 PF16942.5 KIY68286.1 - 0.028 14.7 0.0 0.81 10.0 0.0 2.4 2 0 0 2 2 2 0 Putative cyclic bacteriocin TPR_16 PF13432.6 KIY68286.1 - 0.18 12.4 8.7 2.5 8.8 0.1 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 KIY68286.1 - 1.3 10.1 11.7 45 5.2 0.0 6.4 6 0 0 6 6 6 0 Tetratricopeptide repeat CHAT PF12770.7 KIY68287.1 - 9.1e-43 146.7 0.1 1.6e-42 145.9 0.1 1.4 1 0 0 1 1 1 1 CHAT domain TPR_10 PF13374.6 KIY68287.1 - 4.8e-15 54.9 8.7 0.22 11.5 0.0 8.9 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_12 PF13424.6 KIY68287.1 - 0.00036 20.8 11.9 0.012 15.8 0.4 6.8 3 1 6 9 9 9 1 Tetratricopeptide repeat TPR_2 PF07719.17 KIY68287.1 - 0.014 15.5 7.3 21 5.5 0.0 6.8 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_8 PF13181.6 KIY68287.1 - 0.03 14.5 1.3 93 3.6 0.0 5.9 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_19 PF14559.6 KIY68287.1 - 1.6 9.3 4.3 1e+02 3.5 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat RT_RNaseH PF17917.1 KIY68288.1 - 1.6e-26 92.6 0.0 3.4e-26 91.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 KIY68288.1 - 3.2e-15 56.0 0.6 8.9e-15 54.6 0.6 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 KIY68288.1 - 4.1e-14 52.4 0.0 9.3e-14 51.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 KIY68288.1 - 4.1e-08 33.4 0.2 1.5e-07 31.6 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain Retrotrans_gag PF03732.17 KIY68288.1 - 0.0066 16.7 0.1 0.066 13.5 0.2 2.5 2 0 0 2 2 2 1 Retrotransposon gag protein RVT_1 PF00078.27 KIY68288.1 - 0.0071 15.9 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_3 PF13456.6 KIY68288.1 - 0.028 14.2 0.0 0.056 13.2 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase-like TPR_10 PF13374.6 KIY68289.1 - 1.3e-06 28.0 1.0 0.043 13.7 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 KIY68289.1 - 0.0065 16.6 0.8 0.21 11.9 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 KIY68289.1 - 0.035 13.8 0.8 1.8 8.3 0.2 3.4 3 0 0 3 3 3 0 TPR repeat TPR_2 PF07719.17 KIY68289.1 - 0.071 13.3 1.9 3.2 8.1 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat CbiA PF01656.23 KIY68289.1 - 0.077 13.1 0.0 0.15 12.1 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain CHAT PF12770.7 KIY68290.1 - 1.8e-35 122.8 0.1 3.1e-34 118.7 0.1 2.4 1 1 0 1 1 1 1 CHAT domain TPR_10 PF13374.6 KIY68290.1 - 3.8e-10 39.3 4.3 9.1 6.3 0.0 9.5 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_8 PF13181.6 KIY68290.1 - 1.1e-05 25.2 0.0 0.51 10.7 0.0 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat Sel1 PF08238.12 KIY68290.1 - 0.0049 17.5 0.0 11 6.9 0.0 4.3 4 0 0 4 4 4 1 Sel1 repeat TPR_2 PF07719.17 KIY68290.1 - 0.05 13.7 6.9 11 6.4 0.0 6.6 7 0 0 7 7 7 0 Tetratricopeptide repeat MIT PF04212.18 KIY68290.1 - 0.14 12.2 0.1 35 4.6 0.0 3.8 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain DUF3007 PF11460.8 KIY68290.1 - 0.16 12.2 0.1 2.5 8.4 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3007) ORC2 PF04084.14 KIY68291.1 - 2.1e-84 283.3 0.0 2.5e-84 283.0 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 K_trans PF02705.16 KIY68292.1 - 6.6e-169 562.8 14.0 9e-169 562.4 14.0 1.2 1 0 0 1 1 1 1 K+ potassium transporter F-box-like PF12937.7 KIY68293.1 - 3.3e-08 33.3 0.6 1.1e-07 31.6 0.6 2.0 1 1 0 1 1 1 1 F-box-like Lipase_GDSL_3 PF14606.6 KIY68293.1 - 0.076 13.2 0.0 0.22 11.7 0.0 1.7 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family F-box PF00646.33 KIY68293.1 - 1.8 8.6 4.6 8.6 6.4 0.1 2.6 2 0 0 2 2 2 0 F-box domain MFS_1 PF07690.16 KIY68294.1 - 8.2e-21 74.3 38.6 4.5e-16 58.7 19.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Reprolysin_4 PF13583.6 KIY68295.1 - 4.2e-49 167.0 2.5 8.6e-49 165.9 2.5 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KIY68295.1 - 9.2e-47 159.7 8.6 9.2e-47 159.7 8.6 2.7 2 1 1 3 3 3 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 KIY68295.1 - 3.4e-42 144.6 4.8 3.4e-42 144.6 4.8 2.2 2 1 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 KIY68295.1 - 8.4e-16 58.5 26.4 8.4e-16 58.5 26.4 4.7 3 1 0 3 3 3 1 Disintegrin Reprolysin_3 PF13582.6 KIY68295.1 - 2.2e-13 50.8 1.5 7.3e-13 49.1 0.1 2.5 2 1 1 3 3 3 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.19 KIY68295.1 - 3.4e-06 27.1 7.6 1.6e-05 24.9 7.6 2.1 1 1 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Pep_M12B_propep PF01562.19 KIY68295.1 - 3.2e-05 24.2 0.0 6.3e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Reprolysin family propeptide ADAM_CR_2 PF17771.1 KIY68295.1 - 0.0026 18.2 13.2 0.0026 18.2 13.2 4.1 2 1 1 3 3 3 1 ADAM cysteine-rich domain Peptidase_M66 PF10462.9 KIY68295.1 - 0.1 11.5 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 Peptidase M66 Stealth_CR2 PF11380.8 KIY68296.1 - 2.3e-10 40.6 0.1 6e-07 29.6 0.0 3.3 4 0 0 4 4 4 2 Stealth protein CR2, conserved region 2 Stealth_CR3 PF17102.5 KIY68296.1 - 1.8e-08 34.1 0.5 1.8e-08 34.1 0.5 1.8 2 0 0 2 2 2 1 Stealth protein CR3, conserved region 3 Stealth_CR1 PF17101.5 KIY68296.1 - 0.0015 18.2 0.0 0.0035 17.0 0.0 1.7 1 0 0 1 1 1 1 Stealth protein CR1, conserved region 1 Stealth_CR4 PF17103.5 KIY68296.1 - 0.047 13.6 0.1 0.097 12.6 0.1 1.5 1 0 0 1 1 1 0 Stealth protein CR4, conserved region 4 DJ-1_PfpI PF01965.24 KIY68297.1 - 3.2e-15 56.3 0.0 4.3e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family DPBB_1 PF03330.18 KIY68298.1 - 0.037 14.3 0.0 0.046 14.0 0.0 1.3 1 1 0 1 1 1 0 Lytic transglycolase Ndc80_HEC PF03801.13 KIY68300.1 - 2.8e-24 85.5 0.1 1.6e-23 83.0 0.0 2.1 2 0 0 2 2 2 1 HEC/Ndc80p family DUF5631 PF18645.1 KIY68300.1 - 0.16 12.4 4.0 0.47 10.9 0.1 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5631) Pkinase PF00069.25 KIY68301.1 - 6.8e-44 150.2 0.0 3e-43 148.1 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY68301.1 - 4.1e-24 85.3 0.0 1.4e-23 83.5 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY68301.1 - 2.4e-05 23.8 0.0 3.3e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KIY68301.1 - 3.8e-05 23.7 0.0 7.1e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KIY68301.1 - 0.00028 19.8 0.0 0.00043 19.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 KIY68301.1 - 0.00063 19.4 0.0 0.00093 18.8 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Pox_ser-thr_kin PF05445.11 KIY68301.1 - 0.12 11.3 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase F-box-like PF12937.7 KIY68303.1 - 4e-05 23.4 0.2 0.00029 20.7 0.0 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIY68303.1 - 8.5e-05 22.3 0.1 0.0003 20.6 0.1 2.0 1 0 0 1 1 1 1 F-box domain Rtf2 PF04641.12 KIY68305.1 - 0.0045 16.4 3.3 0.005 16.3 3.3 1.0 1 0 0 1 1 1 1 Rtf2 RING-finger PIN_4 PF13638.6 KIY68305.1 - 0.052 13.8 2.9 0.066 13.5 2.9 1.1 1 0 0 1 1 1 0 PIN domain GspL_C PF12693.7 KIY68306.1 - 0.02 14.8 0.1 0.021 14.7 0.1 1.1 1 0 0 1 1 1 0 GspL periplasmic domain AP-5_subunit_s1 PF15001.6 KIY68307.1 - 0.18 11.7 2.4 0.37 10.7 2.4 1.4 1 0 0 1 1 1 0 AP-5 complex subunit sigma-1 Kelch_6 PF13964.6 KIY68308.1 - 3.4e-20 71.6 5.3 7.4e-05 22.9 0.0 5.6 4 1 1 5 5 5 4 Kelch motif Kelch_4 PF13418.6 KIY68308.1 - 6.2e-20 70.9 4.6 3.4e-06 27.0 0.0 4.9 4 1 1 5 5 5 4 Galactose oxidase, central domain Kelch_1 PF01344.25 KIY68308.1 - 4.5e-19 67.8 3.3 4.6e-06 26.1 0.1 5.1 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.15 KIY68308.1 - 3.9e-15 55.1 1.5 0.0011 18.8 0.0 5.7 5 0 0 5 5 5 3 Kelch motif Kelch_5 PF13854.6 KIY68308.1 - 2.7e-13 49.6 0.9 0.00047 20.1 0.0 4.5 4 0 0 4 4 4 3 Kelch motif Kelch_3 PF13415.6 KIY68308.1 - 3.6e-08 33.5 11.3 0.00021 21.5 0.0 6.1 6 1 0 6 6 6 2 Galactose oxidase, central domain Fibrinogen_C PF00147.18 KIY68308.1 - 0.12 12.2 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Fibrinogen beta and gamma chains, C-terminal globular domain Putative_PNPOx PF01243.20 KIY68309.1 - 4.3e-20 71.7 0.0 6.5e-20 71.1 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PNP_phzG_C PF10590.9 KIY68309.1 - 1.4e-18 66.7 2.9 3.3e-18 65.5 2.9 1.7 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxase_2 PF12766.7 KIY68309.1 - 1.2e-05 25.8 0.0 2.2e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyrid_ox_like PF16242.5 KIY68309.1 - 0.018 14.7 0.0 0.03 13.9 0.0 1.4 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase like DCP1 PF06058.13 KIY68311.1 - 3.7e-26 91.3 0.0 2.1e-25 89.0 0.0 2.0 1 1 0 1 1 1 1 Dcp1-like decapping family MR_MLE_N PF02746.16 KIY68311.1 - 0.21 11.8 0.5 0.4 10.9 0.5 1.4 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain HNH_2 PF13391.6 KIY68312.1 - 0.11 12.6 0.0 0.27 11.4 0.0 1.7 1 0 0 1 1 1 0 HNH endonuclease Sec1 PF00995.23 KIY68314.1 - 7.2e-124 415.1 0.0 8.3e-124 414.9 0.0 1.0 1 0 0 1 1 1 1 Sec1 family EF-hand_14 PF17959.1 KIY68314.1 - 0.096 13.0 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain F-box-like PF12937.7 KIY68315.1 - 2e-07 30.8 1.4 3.4e-07 30.0 1.4 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY68315.1 - 0.017 15.0 0.9 0.054 13.4 0.9 1.8 1 1 0 1 1 1 0 F-box domain Sec2p PF06428.11 KIY68316.1 - 6.4e-09 35.7 11.6 6.4e-09 35.7 11.6 4.1 2 2 1 4 4 4 1 GDP/GTP exchange factor Sec2p ISG65-75 PF11727.8 KIY68316.1 - 0.00065 19.0 4.4 0.00065 19.0 4.4 2.1 2 0 0 2 2 2 1 Invariant surface glycoprotein NBP1 PF08537.10 KIY68316.1 - 0.011 15.1 1.5 0.011 15.1 1.5 2.4 2 0 0 2 2 2 0 Fungal Nap binding protein NBP1 DUF641 PF04859.12 KIY68316.1 - 0.026 14.8 3.4 0.026 14.8 3.4 2.6 2 1 0 2 2 1 0 Plant protein of unknown function (DUF641) ADIP PF11559.8 KIY68316.1 - 0.17 12.0 22.3 0.59 10.2 1.7 2.4 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding NAP PF00956.18 KIY68316.1 - 0.2 10.8 2.7 0.19 10.9 0.3 1.9 2 0 0 2 2 2 0 Nucleosome assembly protein (NAP) Exonuc_VII_L PF02601.15 KIY68316.1 - 0.46 10.0 9.9 0.44 10.1 3.7 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF1043 PF06295.12 KIY68316.1 - 0.73 9.8 10.8 0.16 12.0 6.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) DUF4407 PF14362.6 KIY68316.1 - 2.7 7.3 14.9 1.4 8.2 5.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Herpes_UL25 PF01499.16 KIY68316.1 - 5.9 5.3 7.3 0.62 8.5 1.9 1.9 2 0 0 2 2 2 0 Herpesvirus UL25 family Spc7 PF08317.11 KIY68316.1 - 6.2 5.6 26.8 4.9 5.9 13.9 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein CENP-K PF11802.8 KIY68316.1 - 6.8 6.2 16.4 1.2 8.6 8.1 2.1 2 0 0 2 2 2 0 Centromere-associated protein K FapA PF03961.13 KIY68316.1 - 9.4 4.7 18.4 0.66 8.5 8.2 2.0 2 0 0 2 2 2 0 Flagellar Assembly Protein A dCMP_cyt_deam_1 PF00383.23 KIY68317.1 - 9.3e-21 73.6 0.1 1.2e-20 73.2 0.1 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KIY68317.1 - 9.9e-18 64.2 0.0 1.2e-17 64.0 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase SNAD4 PF18750.1 KIY68317.1 - 2.9e-05 24.1 0.0 4.5e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 NAD2 PF18782.1 KIY68317.1 - 0.00011 22.4 0.0 0.00016 21.9 0.0 1.2 1 0 0 1 1 1 1 Novel AID APOBEC clade 2 Bd3614-deam PF14439.6 KIY68317.1 - 0.00018 21.6 4.4 0.061 13.4 0.1 2.2 1 1 1 2 2 2 2 Bd3614-like deaminase APOBEC2 PF18772.1 KIY68317.1 - 0.0013 18.8 0.0 0.0018 18.4 0.0 1.2 1 0 0 1 1 1 1 APOBEC2 NAD1 PF18778.1 KIY68317.1 - 0.004 17.2 0.0 0.0057 16.8 0.0 1.2 1 0 0 1 1 1 1 Novel AID APOBEC clade 1 APOBEC3 PF18771.1 KIY68317.1 - 0.0047 17.1 0.0 0.0068 16.5 0.0 1.2 1 0 0 1 1 1 1 APOBEC3 APOBEC_N PF08210.11 KIY68317.1 - 0.018 15.0 0.0 0.021 14.7 0.0 1.1 1 0 0 1 1 1 0 APOBEC-like N-terminal domain Pkinase PF00069.25 KIY68318.1 - 7.3e-60 202.6 0.0 1.2e-59 201.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY68318.1 - 1.3e-30 106.5 0.0 2.4e-30 105.7 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIY68318.1 - 0.0032 16.3 0.0 0.0045 15.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KIY68318.1 - 0.021 14.2 0.0 0.054 12.8 0.0 1.5 1 1 0 1 1 1 0 Kinase-like Seadorna_VP7 PF07387.11 KIY68318.1 - 0.075 12.1 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 KIY68318.1 - 0.21 11.5 0.0 0.36 10.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KIY68318.1 - 0.27 10.1 0.0 0.43 9.5 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain PTPA PF03095.15 KIY68319.1 - 5e-127 423.5 0.0 5.7e-127 423.3 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein FAD_binding_3 PF01494.19 KIY68320.1 - 1.2e-13 51.1 0.0 7e-12 45.3 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 KIY68320.1 - 3.3e-07 30.2 0.1 0.0025 17.5 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIY68320.1 - 5.4e-05 22.6 0.8 0.00075 18.8 0.3 2.1 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KIY68320.1 - 0.00056 19.1 0.2 0.0029 16.8 0.3 1.9 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 KIY68320.1 - 0.00061 18.9 0.1 0.1 11.6 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein HI0933_like PF03486.14 KIY68320.1 - 0.00075 18.3 0.1 0.72 8.5 0.1 2.1 2 0 0 2 2 2 2 HI0933-like protein Amino_oxidase PF01593.24 KIY68320.1 - 0.00075 18.9 0.4 0.037 13.3 0.4 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KIY68320.1 - 0.0015 18.7 0.8 0.0044 17.2 0.8 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KIY68320.1 - 0.041 14.4 0.3 0.14 12.8 0.3 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KIY68320.1 - 0.045 13.1 0.5 0.074 12.4 0.5 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KIY68320.1 - 0.14 11.4 0.1 0.93 8.7 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KIY68320.1 - 0.18 10.8 0.3 0.28 10.2 0.3 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Cys_Met_Meta_PP PF01053.20 KIY68322.1 - 9.3e-142 472.1 0.0 1.1e-141 471.9 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KIY68322.1 - 1.7e-10 40.8 0.2 3.6e-10 39.7 0.2 1.5 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 KIY68322.1 - 2.2e-10 40.3 0.1 4.2e-10 39.3 0.1 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KIY68322.1 - 1.2e-08 34.3 0.6 1.8e-08 33.8 0.2 1.6 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KIY68322.1 - 1.3e-07 31.3 0.0 2.7e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.11 KIY68322.1 - 0.0032 16.0 0.1 0.0043 15.6 0.1 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase SepSecS PF05889.13 KIY68322.1 - 0.054 12.2 0.0 0.075 11.7 0.0 1.1 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS GDC-P PF02347.16 KIY68322.1 - 0.06 12.2 0.0 0.085 11.7 0.0 1.1 1 0 0 1 1 1 0 Glycine cleavage system P-protein ABC_sub_bind PF04392.12 KIY68322.1 - 0.094 11.9 0.4 0.23 10.7 0.0 1.7 2 0 0 2 2 2 0 ABC transporter substrate binding protein Fungal_trans PF04082.18 KIY68323.1 - 4.2e-20 71.9 0.1 7.8e-20 71.0 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY68323.1 - 0.0001 22.3 13.6 0.0001 22.3 13.6 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HSBP1 PF06825.12 KIY68323.1 - 0.038 13.8 1.0 0.13 12.2 0.1 2.1 2 0 0 2 2 2 0 Heat shock factor binding protein 1 Fungal_trans PF04082.18 KIY68324.1 - 2.8e-14 52.8 0.0 6.5e-14 51.6 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain EAP30 PF04157.16 KIY68325.1 - 1.2e-36 126.2 0.0 1.9e-36 125.6 0.0 1.3 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.8 KIY68325.1 - 2.3e-16 59.7 0.0 4.4e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 zf-RanBP PF00641.18 KIY68325.1 - 1.8e-06 27.2 5.3 0.0033 16.7 1.8 2.5 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others Vps36-NZF-N PF16988.5 KIY68325.1 - 0.0072 15.7 6.8 0.013 14.8 0.1 3.0 2 1 1 3 3 3 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain DZR PF12773.7 KIY68325.1 - 2.6 8.1 8.0 11 6.1 8.1 2.0 1 1 0 1 1 1 0 Double zinc ribbon zf-Sec23_Sec24 PF04810.15 KIY68325.1 - 3 8.0 8.2 18 5.5 1.7 3.1 3 1 0 3 3 3 0 Sec23/Sec24 zinc finger Amidohydro_1 PF01979.20 KIY68326.1 - 4.8e-43 147.8 0.0 5.7e-43 147.5 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KIY68326.1 - 0.00018 21.1 0.1 0.031 13.8 0.1 2.1 2 0 0 2 2 2 2 Amidohydrolase family NmrA PF05368.13 KIY68327.1 - 9.8e-16 58.0 0.0 1.3e-15 57.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KIY68327.1 - 8.5e-07 29.0 0.0 1.2e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding BPS PF08947.10 KIY68328.1 - 0.019 14.8 0.6 0.056 13.3 0.6 1.8 1 0 0 1 1 1 0 BPS (Between PH and SH2) SlyX PF04102.12 KIY68328.1 - 0.083 13.5 0.6 0.083 13.5 0.6 3.2 2 1 1 3 3 3 0 SlyX DUF16 PF01519.16 KIY68328.1 - 9.4 6.8 9.4 3.1e+02 1.9 9.4 2.4 1 1 0 1 1 1 0 Protein of unknown function DUF16 COPIIcoated_ERV PF07970.12 KIY68329.1 - 3.7e-80 268.9 0.1 5.4e-80 268.4 0.1 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 KIY68329.1 - 2.3e-26 91.9 0.1 2.3e-26 91.9 0.1 1.8 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) CAF1 PF04857.20 KIY68330.1 - 1.1e-20 74.1 0.2 2.4e-11 43.4 0.0 2.5 1 1 1 2 2 2 2 CAF1 family ribonuclease RNase_H_2 PF13482.6 KIY68330.1 - 0.0024 17.9 0.0 0.0038 17.2 0.0 1.3 1 0 0 1 1 1 1 RNase_H superfamily AAA_16 PF13191.6 KIY68331.1 - 0.012 16.1 0.0 0.025 15.0 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.12 KIY68331.1 - 0.024 13.9 0.0 0.037 13.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.12 KIY68331.1 - 0.13 12.2 0.0 0.43 10.5 0.0 1.8 2 0 0 2 2 2 0 NACHT domain AAA_22 PF13401.6 KIY68331.1 - 0.13 12.5 0.0 0.21 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 KIY68331.1 - 0.25 10.3 0.0 0.36 9.8 0.0 1.1 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB SH3_9 PF14604.6 KIY68332.1 - 4.2e-25 87.4 0.3 5.1e-14 51.9 0.1 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 KIY68332.1 - 4e-22 77.5 0.2 6.1e-11 41.8 0.1 2.5 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 KIY68332.1 - 1.3e-17 63.2 0.1 3.5e-09 36.2 0.1 2.4 2 0 0 2 2 2 2 Variant SH3 domain FCH PF00611.23 KIY68332.1 - 9.4e-16 57.9 2.1 1.4e-15 57.3 0.3 2.3 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain C1_1 PF00130.22 KIY68332.1 - 2e-12 46.8 5.1 3.2e-12 46.1 5.1 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_3 PF08239.11 KIY68332.1 - 0.00071 19.8 0.0 0.0015 18.8 0.0 1.5 1 0 0 1 1 1 1 Bacterial SH3 domain AMA-1 PF02430.15 KIY68332.1 - 0.0037 16.3 1.4 0.006 15.6 1.4 1.3 1 0 0 1 1 1 1 Apical membrane antigen 1 PHD_2 PF13831.6 KIY68332.1 - 0.23 11.0 2.3 0.57 9.8 2.3 1.6 1 0 0 1 1 1 0 PHD-finger C1_2 PF03107.16 KIY68332.1 - 0.25 11.7 2.3 0.56 10.6 2.3 1.6 1 0 0 1 1 1 0 C1 domain Sugar_tr PF00083.24 KIY68333.1 - 2.1e-125 419.2 20.9 5.3e-125 417.8 20.9 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY68333.1 - 6.9e-17 61.4 35.0 4.3e-11 42.3 10.9 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2530 PF10745.9 KIY68333.1 - 0.34 11.2 6.0 0.19 12.0 0.7 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) GPI-anchored PF10342.9 KIY68334.1 - 7.2e-06 26.7 0.0 7.2e-06 26.7 0.0 2.1 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.6 KIY68334.1 - 0.058 13.2 0.0 0.14 11.9 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) Carn_acyltransf PF00755.20 KIY68335.1 - 9.7e-193 642.0 0.0 1.1e-192 641.8 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase zf-C2H2_4 PF13894.6 KIY68336.1 - 0.00014 22.4 0.2 0.019 15.7 0.0 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger DUF4606 PF15379.6 KIY68336.1 - 0.0027 17.9 1.0 0.047 13.9 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4606) zf-C2H2 PF00096.26 KIY68336.1 - 0.0056 17.1 0.3 0.33 11.5 0.0 2.5 2 0 0 2 2 2 1 Zinc finger, C2H2 type Tup_N PF08581.10 KIY68336.1 - 0.021 15.1 4.3 0.56 10.6 3.1 2.2 1 1 1 2 2 2 0 Tup N-terminal JAKMIP_CC3 PF16034.5 KIY68336.1 - 0.021 14.8 0.9 0.033 14.1 0.9 1.2 1 0 0 1 1 1 0 JAKMIP CC3 domain Casc1_N PF15927.5 KIY68336.1 - 0.025 14.3 1.5 0.036 13.7 1.5 1.2 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus zf-Di19 PF05605.12 KIY68336.1 - 0.033 14.5 0.9 0.059 13.7 0.9 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding DZR PF12773.7 KIY68336.1 - 0.062 13.3 0.4 0.12 12.4 0.4 1.4 1 0 0 1 1 1 0 Double zinc ribbon OrfB_Zn_ribbon PF07282.11 KIY68336.1 - 0.15 12.0 0.2 0.28 11.1 0.2 1.4 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Aldo_ket_red PF00248.21 KIY68338.1 - 5e-71 239.3 0.0 5.7e-71 239.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Peptidase_C39 PF03412.15 KIY68338.1 - 0.021 14.7 0.0 0.047 13.5 0.0 1.5 1 0 0 1 1 1 0 Peptidase C39 family Aldo_ket_red PF00248.21 KIY68339.1 - 9e-73 245.0 0.0 1e-72 244.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Ribosomal_L23 PF00276.20 KIY68341.1 - 1e-10 41.8 0.0 2.3e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L23 F-box-like PF12937.7 KIY68341.1 - 2.9e-05 23.8 0.2 7.2e-05 22.6 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KIY68342.1 - 4e-06 26.6 0.5 8.9e-06 25.5 0.5 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY68342.1 - 4.2e-05 23.3 1.0 0.00011 21.9 1.0 1.7 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KIY68342.1 - 0.025 14.4 0.2 0.075 12.9 0.1 1.7 2 0 0 2 2 2 0 F-box Aminotran_1_2 PF00155.21 KIY68343.1 - 3.1e-40 138.5 0.0 4.1e-40 138.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KIY68343.1 - 0.00072 18.2 0.0 0.0012 17.5 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Zn_clus PF00172.18 KIY68344.1 - 2.4e-06 27.6 7.1 3.1e-06 27.2 7.1 1.1 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GMP_synt_C PF00958.22 KIY68346.1 - 6.8e-44 147.8 0.2 1.2e-43 147.1 0.2 1.4 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 KIY68346.1 - 5.4e-37 127.4 0.0 1e-36 126.5 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.17 KIY68346.1 - 1.3e-11 44.1 0.1 1.8e-06 27.3 0.0 2.3 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 KIY68346.1 - 3.4e-11 43.3 0.0 7.3e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 tRNA_Me_trans PF03054.16 KIY68346.1 - 0.0036 16.1 0.1 0.0064 15.3 0.1 1.4 1 0 0 1 1 1 1 tRNA methyl transferase QueC PF06508.13 KIY68346.1 - 0.0043 16.6 0.0 0.046 13.2 0.0 2.0 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC ThiI PF02568.14 KIY68346.1 - 0.016 14.8 0.1 0.031 13.9 0.1 1.4 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) HOASN PF14515.6 KIY68346.1 - 0.1 13.0 0.3 0.21 12.0 0.3 1.4 1 0 0 1 1 1 0 Haem-oxygenase-associated N-terminal helices ATP_bind_3 PF01171.20 KIY68346.1 - 0.14 11.9 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 PP-loop family Arginosuc_synth PF00764.19 KIY68346.1 - 0.16 11.2 0.1 0.28 10.4 0.1 1.3 1 0 0 1 1 1 0 Arginosuccinate synthase sCache_like PF16736.5 KIY68346.1 - 0.22 11.6 0.0 0.41 10.7 0.0 1.4 1 0 0 1 1 1 0 Single Cache-like Herpes_UL37_2 PF07413.11 KIY68346.1 - 0.23 10.7 0.0 0.36 10.0 0.0 1.2 1 0 0 1 1 1 0 Betaherpesvirus immediate-early glycoprotein UL37 SGL PF08450.12 KIY68347.1 - 9.6e-25 87.6 0.0 1.4e-24 87.0 0.0 1.3 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 KIY68347.1 - 9.5e-05 22.4 0.0 0.00025 21.1 0.0 1.8 1 0 0 1 1 1 1 Strictosidine synthase Arylesterase PF01731.20 KIY68347.1 - 0.00068 19.8 0.0 0.0023 18.1 0.0 1.8 1 0 0 1 1 1 1 Arylesterase Kelch_3 PF13415.6 KIY68347.1 - 0.0014 18.9 3.4 4.4 7.7 0.2 3.5 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_4 PF13418.6 KIY68347.1 - 0.0018 18.2 0.6 22 5.2 0.1 3.5 3 0 0 3 3 3 2 Galactose oxidase, central domain BAG PF02179.16 KIY68348.1 - 8.6e-09 35.7 0.0 2.9e-08 34.0 0.0 1.9 1 0 0 1 1 1 1 BAG domain HTH_ABP1_N PF18107.1 KIY68348.1 - 0.2 11.4 0.6 0.5 10.1 0.6 1.7 1 0 0 1 1 1 0 Fission yeast centromere protein N-terminal domain CLTH PF10607.9 KIY68349.1 - 1.4e-24 86.6 0.0 2.6e-24 85.8 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain Metallophos PF00149.28 KIY68350.1 - 4.1e-14 53.6 0.4 9.6e-14 52.4 0.4 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KIY68350.1 - 1.6e-05 25.1 0.0 0.0014 18.9 0.0 2.3 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain Mito_fiss_reg PF05308.11 KIY68352.1 - 0.63 10.1 6.9 0.12 12.4 1.3 1.9 1 1 1 2 2 2 0 Mitochondrial fission regulator DUF1192 PF06698.11 KIY68352.1 - 4 7.6 6.5 0.18 11.9 0.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) E1-E2_ATPase PF00122.20 KIY68356.1 - 2.6 7.5 5.4 16 5.0 4.3 2.1 2 0 0 2 2 2 0 E1-E2 ATPase Trypsin_2 PF13365.6 KIY68358.1 - 0.00027 21.9 0.2 0.0075 17.2 0.2 2.5 1 1 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_S32 PF05579.13 KIY68358.1 - 0.0013 18.0 0.0 0.0023 17.2 0.0 1.3 1 0 0 1 1 1 1 Equine arteritis virus serine endopeptidase S32 Peptidase_S3 PF00944.19 KIY68358.1 - 0.18 11.6 0.1 0.36 10.6 0.1 1.5 1 0 0 1 1 1 0 Alphavirus core protein BUD22 PF09073.10 KIY68359.1 - 0.38 10.0 5.2 0.45 9.8 5.2 1.1 1 0 0 1 1 1 0 BUD22 adh_short PF00106.25 KIY68360.1 - 2.9e-44 150.9 0.4 3.9e-44 150.5 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIY68360.1 - 2.1e-32 112.6 0.1 3e-32 112.1 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIY68360.1 - 1.1e-08 35.2 0.5 3.6e-08 33.5 0.5 1.8 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 KIY68360.1 - 0.013 14.9 0.0 0.2 11.0 0.0 2.1 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) ADH_zinc_N PF00107.26 KIY68360.1 - 0.044 13.8 0.2 0.33 10.9 0.0 2.1 1 1 1 2 2 2 0 Zinc-binding dehydrogenase MFS_1 PF07690.16 KIY68361.1 - 2.1e-40 138.8 50.5 4.5e-40 137.6 50.5 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIY68361.1 - 2.4e-08 33.3 16.6 2.4e-08 33.3 16.6 3.8 2 2 1 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 KIY68361.1 - 3.7e-07 29.0 15.2 4.9e-07 28.6 15.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 KIY68361.1 - 1.7 6.9 21.0 0.0095 14.3 4.5 2.9 2 2 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family F-box PF00646.33 KIY68362.1 - 0.003 17.4 0.2 0.014 15.2 0.2 2.1 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KIY68362.1 - 0.0092 15.9 0.2 0.028 14.3 0.0 1.9 2 0 0 2 2 2 1 F-box-like pPIWI_RE_Z PF18155.1 KIY68362.1 - 0.13 12.2 0.1 0.7 9.7 0.0 2.1 2 0 0 2 2 2 0 pPIWI RE three-gene island domain Z TauD PF02668.16 KIY68363.1 - 8.2e-51 173.4 0.4 1e-50 173.0 0.4 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family adh_short PF00106.25 KIY68364.1 - 1.5e-43 148.6 0.0 2e-43 148.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIY68364.1 - 5.7e-32 111.1 0.0 7e-32 110.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 KIY68364.1 - 5.4e-08 32.6 0.0 5.9e-07 29.1 0.0 2.0 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) KR PF08659.10 KIY68364.1 - 1.6e-07 31.4 0.1 2.4e-07 30.8 0.1 1.2 1 0 0 1 1 1 1 KR domain ADH_zinc_N PF00107.26 KIY68364.1 - 0.015 15.3 0.1 0.13 12.3 0.0 2.2 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Epimerase PF01370.21 KIY68364.1 - 0.056 12.9 0.1 0.24 10.8 0.1 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KIY68364.1 - 0.089 11.9 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain TauD PF02668.16 KIY68365.1 - 2.9e-49 168.3 0.4 3.6e-49 168.0 0.4 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Fungal_trans PF04082.18 KIY68366.1 - 2.9e-17 62.6 0.0 4.6e-17 61.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Mito_carr PF00153.27 KIY68368.1 - 2.5e-27 94.6 8.1 6e-17 61.4 0.1 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein Mito_carr PF00153.27 KIY68369.1 - 5.1e-30 103.2 6.2 2.5e-17 62.5 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4203 PF13886.6 KIY68369.1 - 0.11 12.1 2.1 0.11 12.1 0.1 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4203) Deltameth_res PF16020.5 KIY68369.1 - 0.13 12.2 0.1 0.5 10.3 0.0 2.1 2 0 0 2 2 2 0 Deltamethrin resistance AMP-binding PF00501.28 KIY68370.1 - 8.4e-88 294.8 0.1 1.1e-87 294.4 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KIY68370.1 - 9.2e-12 45.8 0.5 2.9e-11 44.2 0.5 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain F-box-like PF12937.7 KIY68371.1 - 8.6e-05 22.4 1.9 0.00093 19.0 1.9 2.6 1 1 0 1 1 1 1 F-box-like F-box_5 PF18511.1 KIY68371.1 - 0.049 13.2 0.4 0.049 13.2 0.4 1.6 2 0 0 2 2 2 0 F-box G-alpha PF00503.20 KIY68372.1 - 7.6e-91 304.9 0.0 9.1e-91 304.6 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KIY68372.1 - 9.6e-13 48.0 0.1 2.4e-07 30.4 0.0 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family AAA_29 PF13555.6 KIY68372.1 - 0.001 18.8 0.0 0.093 12.5 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF815 PF05673.13 KIY68372.1 - 0.0027 16.9 0.1 0.0047 16.1 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Roc PF08477.13 KIY68372.1 - 0.012 15.8 0.0 1.5 9.1 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 KIY68372.1 - 0.014 14.9 0.0 0.024 14.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AAA_24 PF13479.6 KIY68372.1 - 0.037 13.7 0.0 0.071 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain PAP2 PF01569.21 KIY68373.1 - 7.4e-16 58.1 9.6 2e-15 56.7 9.6 1.7 1 0 0 1 1 1 1 PAP2 superfamily LRR_8 PF13855.6 KIY68376.1 - 4.9e-07 29.4 2.2 5.4e-07 29.3 0.8 1.9 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 KIY68376.1 - 9.3e-07 29.1 3.0 3.9e-05 23.9 0.2 3.3 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) zf-CSL PF05207.13 KIY68376.1 - 0.074 12.8 0.1 0.16 11.7 0.1 1.5 1 0 0 1 1 1 0 CSL zinc finger DHBP_synthase PF00926.19 KIY68377.1 - 1.1e-85 286.0 0.0 1.3e-85 285.8 0.0 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase PS_Dcarbxylase PF02666.15 KIY68378.1 - 1.4e-46 158.5 0.0 2.3e-46 157.9 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase TraK PF06586.11 KIY68379.1 - 0.068 12.9 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 TraK protein ADH_zinc_N PF00107.26 KIY68380.1 - 7.8e-23 80.9 0.2 1.3e-22 80.1 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KIY68380.1 - 4.5e-16 58.7 0.0 9.3e-16 57.7 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 KIY68380.1 - 1.6e-11 45.4 0.0 2.5e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Asp PF00026.23 KIY68381.1 - 1.1e-67 228.7 3.3 1.4e-67 228.4 3.3 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIY68381.1 - 2.5e-10 40.9 4.2 2e-09 37.9 1.0 2.8 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KIY68381.1 - 0.063 13.9 5.9 3.2 8.5 0.2 3.6 2 1 0 3 3 3 0 Aspartyl protease SBF_like PF13593.6 KIY68384.1 - 3.2e-86 289.5 24.8 3.7e-86 289.3 24.8 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) DUF2838 PF10998.8 KIY68384.1 - 0.013 15.7 0.9 0.042 14.1 0.9 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2838) Phage_holin_3_1 PF05106.12 KIY68384.1 - 0.21 12.0 5.1 0.31 11.5 0.0 2.9 3 0 0 3 3 3 0 Phage holin family (Lysis protein S) SPC25 PF06703.11 KIY68385.1 - 10 5.9 7.6 0.56 10.0 0.3 2.2 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Alpha-L-AF_C PF06964.12 KIY68387.1 - 2.9e-38 131.6 2.3 5.4e-38 130.7 2.3 1.5 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain CBM_4_9 PF02018.17 KIY68387.1 - 0.0095 16.2 0.1 0.027 14.8 0.0 1.8 2 0 0 2 2 2 1 Carbohydrate binding domain 2OG-FeII_Oxy_2 PF13532.6 KIY68388.1 - 1.5e-16 61.2 0.0 1.9e-16 60.8 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RXT2_N PF08595.11 KIY68389.1 - 8.2 6.4 8.1 24 4.9 0.3 2.3 1 1 1 2 2 2 0 RXT2-like, N-terminal adh_short PF00106.25 KIY68390.1 - 6.1e-44 149.8 0.0 9.4e-44 149.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIY68390.1 - 1.6e-29 103.2 0.0 2.4e-29 102.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIY68390.1 - 1.8e-08 34.5 0.0 4e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KIY68390.1 - 0.0013 18.2 0.0 0.0017 17.8 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 KIY68390.1 - 0.0042 17.0 0.0 0.0057 16.6 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KIY68390.1 - 0.091 12.2 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family PIG-P PF08510.12 KIY68391.1 - 0.82 9.6 8.9 1 9.3 5.0 2.8 2 1 0 2 2 2 0 PIG-P Amidohydro_1 PF01979.20 KIY68393.1 - 4.4e-12 46.0 0.0 2.2e-07 30.5 0.0 3.3 3 0 0 3 3 3 2 Amidohydrolase family Amidohydro_3 PF07969.11 KIY68393.1 - 6.5e-11 42.4 1.6 4.2e-06 26.5 0.0 2.9 3 0 0 3 3 3 2 Amidohydrolase family Oxidored_FMN PF00724.20 KIY68395.1 - 1.9e-72 244.4 0.0 2.4e-72 244.1 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF346 PF03984.13 KIY68395.1 - 0.025 14.3 0.3 0.056 13.2 0.3 1.5 1 0 0 1 1 1 0 Repeat of unknown function (DUF346) 4HBT PF03061.22 KIY68396.1 - 2.8e-09 37.2 0.1 5e-09 36.4 0.1 1.5 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 KIY68396.1 - 0.0068 16.7 0.0 0.008 16.5 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily ESPR PF13018.6 KIY68396.1 - 0.081 12.7 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 Extended Signal Peptide of Type V secretion system PH PF00169.29 KIY68400.1 - 2.8e-14 53.5 0.1 7.7e-14 52.1 0.1 1.7 1 0 0 1 1 1 1 PH domain SH3_1 PF00018.28 KIY68400.1 - 4e-13 48.7 0.6 9.1e-13 47.6 0.6 1.6 1 0 0 1 1 1 1 SH3 domain SAM_1 PF00536.30 KIY68400.1 - 1e-12 48.3 0.1 3.4e-12 46.6 0.1 2.0 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_9 PF14604.6 KIY68400.1 - 1.7e-12 47.0 0.2 3.6e-12 46.0 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain SAM_2 PF07647.17 KIY68400.1 - 3.8e-12 46.1 0.0 9e-12 44.9 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_2 PF07653.17 KIY68400.1 - 1.9e-09 37.1 0.2 4.2e-09 36.0 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain SAM_3 PF18016.1 KIY68400.1 - 0.0011 18.7 0.0 0.0024 17.6 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 KIY68400.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain LRR_4 PF12799.7 KIY68404.1 - 0.094 13.2 0.1 3.3 8.3 0.0 3.4 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) Thiolase_N PF00108.23 KIY68405.1 - 5.4e-74 248.8 2.5 1.1e-73 247.9 1.9 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KIY68405.1 - 5.6e-43 145.5 0.3 1.2e-42 144.5 0.3 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KIY68405.1 - 0.0007 19.2 1.4 0.0092 15.6 0.6 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain VCBS PF13517.6 KIY68406.1 - 3.9e-26 91.4 17.7 4e-10 40.1 0.0 4.7 3 1 2 5 5 5 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Polo_box_2 PF18531.1 KIY68406.1 - 0.041 14.0 0.0 0.081 13.1 0.0 1.5 1 0 0 1 1 1 0 Polo box domain FG-GAP PF01839.23 KIY68406.1 - 0.042 14.0 21.1 1.2 9.3 0.0 6.7 7 0 0 7 7 7 0 FG-GAP repeat Itfg2 PF15907.5 KIY68406.1 - 0.059 12.4 0.1 3.8 6.4 0.0 2.5 3 0 0 3 3 3 0 Integrin-alpha FG-GAP repeat-containing protein 2 TcdB_toxin_midN PF12256.8 KIY68406.1 - 0.19 11.0 6.1 36 3.7 0.0 4.9 3 1 2 5 5 5 0 Insecticide toxin TcdB middle/N-terminal region RepA_C PF04796.12 KIY68407.1 - 0.074 13.1 0.4 0.19 11.8 0.2 1.7 1 1 1 2 2 2 0 Plasmid encoded RepA protein Abhydrolase_1 PF00561.20 KIY68408.1 - 6.9e-22 78.3 0.0 3.4e-17 63.0 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 KIY68408.1 - 2.2e-16 59.8 0.0 5e-16 58.7 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Peptidase_S9 PF00326.21 KIY68408.1 - 0.14 11.6 0.1 0.94 8.9 0.1 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family GRDP-like PF07173.12 KIY68410.1 - 1.9e-21 77.2 1.4 1.8e-16 61.1 0.0 3.1 2 1 1 3 3 3 3 Glycine-rich domain-containing protein-like GRDP-like PF07173.12 KIY68411.1 - 2.9e-21 76.6 0.1 4.3e-16 59.9 0.0 2.7 2 1 0 2 2 2 2 Glycine-rich domain-containing protein-like NUDIX PF00293.28 KIY68412.1 - 5.4e-12 45.9 0.0 1.3e-11 44.7 0.0 1.6 2 0 0 2 2 2 1 NUDIX domain Hydrolase_4 PF12146.8 KIY68414.1 - 2e-15 56.8 0.0 3.2e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KIY68414.1 - 5.3e-15 55.7 0.1 4.2e-11 43.0 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIY68414.1 - 4.4e-13 50.3 1.5 7.9e-13 49.5 1.5 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 KIY68414.1 - 0.00011 21.9 0.0 0.088 12.3 0.0 2.1 2 0 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_5 PF12695.7 KIY68414.1 - 0.0011 18.7 0.0 0.16 11.7 0.0 2.8 3 0 0 3 3 3 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KIY68414.1 - 0.034 13.6 0.0 0.12 11.9 0.0 1.9 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_4 PF08386.10 KIY68414.1 - 0.048 13.8 0.0 0.073 13.2 0.0 1.2 1 0 0 1 1 1 0 TAP-like protein Abhydrolase_2 PF02230.16 KIY68414.1 - 0.081 12.7 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Thaumatin PF00314.17 KIY68415.1 - 1.2e-69 234.2 11.1 1.4e-69 234.0 11.1 1.0 1 0 0 1 1 1 1 Thaumatin family Glyco_hydro_64 PF16483.5 KIY68415.1 - 0.01 15.1 0.0 0.018 14.3 0.0 1.4 1 1 0 1 1 1 0 Beta-1,3-glucanase MBOAT_2 PF13813.6 KIY68416.1 - 3.4e-19 68.9 3.2 1e-18 67.4 3.2 1.9 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Rab5ip PF07019.12 KIY68418.1 - 2.4e-21 76.1 2.4 2.9e-21 75.8 2.4 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) Semialdhyde_dhC PF02774.18 KIY68419.1 - 4.1e-40 137.8 0.0 8.7e-40 136.7 0.0 1.5 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 KIY68419.1 - 4.8e-28 98.0 0.0 8.3e-28 97.3 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DXP_reductoisom PF02670.16 KIY68419.1 - 0.13 13.0 0.1 0.62 10.8 0.0 2.1 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase DapB_N PF01113.20 KIY68419.1 - 0.14 12.3 0.0 0.27 11.4 0.0 1.6 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus RNase_PH PF01138.21 KIY68420.1 - 4.9e-25 88.5 0.0 8.3e-25 87.8 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KIY68420.1 - 7.5e-05 22.7 0.0 0.00013 21.9 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 AAA_16 PF13191.6 KIY68421.1 - 0.027 14.9 0.0 0.055 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 KIY68421.1 - 0.15 11.9 0.0 0.45 10.4 0.0 1.7 1 0 0 1 1 1 0 NACHT domain Peptidase_M24 PF00557.24 KIY68422.1 - 3.9e-45 154.1 0.1 4.5e-45 153.9 0.1 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 DPBB_1 PF03330.18 KIY68423.1 - 3.6e-06 27.1 0.1 5.8e-06 26.5 0.1 1.3 1 0 0 1 1 1 1 Lytic transglycolase Clathrin PF00637.20 KIY68424.1 - 3.6e-25 88.5 0.2 1.6e-24 86.4 0.1 2.2 2 0 0 2 2 2 1 Region in Clathrin and VPS WD40 PF00400.32 KIY68424.1 - 0.00028 21.6 0.0 0.0015 19.3 0.0 2.3 1 0 0 1 1 1 1 WD domain, G-beta repeat zf-RING_2 PF13639.6 KIY68424.1 - 0.00085 19.6 2.5 0.006 16.9 0.6 2.4 2 0 0 2 2 2 1 Ring finger domain Vps39_2 PF10367.9 KIY68424.1 - 0.00097 19.6 0.1 0.0079 16.6 0.0 2.3 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 Zn_ribbon_17 PF17120.5 KIY68424.1 - 0.15 11.7 1.6 0.35 10.5 1.6 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FYVE_2 PF02318.16 KIY68424.1 - 0.17 12.1 0.3 0.5 10.6 0.3 1.8 1 0 0 1 1 1 0 FYVE-type zinc finger Vps39_1 PF10366.9 KIY68424.1 - 0.23 11.8 0.4 7 7.0 0.1 3.0 1 1 2 3 3 3 0 Vacuolar sorting protein 39 domain 1 ART-PolyVal PF18760.1 KIY68424.1 - 0.28 12.2 1.5 14 6.7 0.0 2.7 3 0 0 3 3 3 0 ADP-Ribosyltransferase in polyvalent proteins zf-C3H2C3 PF17122.5 KIY68424.1 - 0.42 10.7 2.5 0.37 10.8 0.1 2.2 2 0 0 2 2 2 0 Zinc-finger zf-C3HC4 PF00097.25 KIY68424.1 - 0.75 9.7 4.9 0.58 10.1 1.7 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KIY68424.1 - 0.78 9.8 5.8 0.15 12.1 0.6 2.3 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING_5 PF14634.6 KIY68424.1 - 0.88 9.6 3.7 4.3 7.4 3.7 2.2 1 1 0 1 1 1 0 zinc-RING finger domain MRI PF15325.6 KIY68424.1 - 1.1 10.4 10.5 4.4 8.4 10.5 2.1 1 0 0 1 1 1 0 Modulator of retrovirus infection zf-C3HC4_2 PF13923.6 KIY68424.1 - 3 7.8 7.4 10 6.0 4.5 2.8 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KIY68424.1 - 3.1 7.8 8.1 8.9 6.3 0.7 3.1 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KIY68424.1 - 4.2 7.3 6.7 3.9 7.4 0.1 2.7 3 0 0 3 3 2 0 Zinc finger, C3HC4 type (RING finger) MAD PF05557.13 KIY68425.1 - 2.8e-40 138.4 62.0 1.2e-38 133.0 62.0 2.0 1 1 0 1 1 1 1 Mitotic checkpoint protein ATG16 PF08614.11 KIY68425.1 - 0.0079 16.4 7.6 0.0079 16.4 7.6 6.3 2 1 3 5 5 5 2 Autophagy protein 16 (ATG16) FliJ PF02050.16 KIY68425.1 - 0.44 10.8 0.1 0.44 10.8 0.1 6.9 3 1 4 7 7 7 0 Flagellar FliJ protein LPP PF04728.13 KIY68425.1 - 1.2 9.5 12.8 1.6 9.1 0.7 5.4 4 1 1 5 5 5 0 Lipoprotein leucine-zipper TMCO5 PF14992.6 KIY68425.1 - 3.6 7.1 63.9 0.15 11.6 6.7 4.2 2 1 1 4 4 4 0 TMCO5 family Spc7 PF08317.11 KIY68425.1 - 3.6 6.4 80.5 0.021 13.7 20.6 5.7 2 1 4 6 6 6 0 Spc7 kinetochore protein AAA-ATPase_like PF09820.9 KIY68426.1 - 0.15 11.4 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Predicted AAA-ATPase fn3_2 PF16893.5 KIY68428.1 - 1.4e-38 130.9 0.2 3.2e-38 129.8 0.2 1.6 2 0 0 2 2 2 1 Fibronectin type III domain CHS5_N PF16892.5 KIY68428.1 - 1.2e-26 92.4 0.1 2.1e-26 91.6 0.1 1.5 1 0 0 1 1 1 1 Chitin biosynthesis protein CHS5 N-terminus BRCT PF00533.26 KIY68428.1 - 1.3e-07 31.9 0.0 2.1e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KIY68428.1 - 4e-06 26.7 0.1 0.0001 22.2 0.0 2.9 2 1 0 2 2 2 1 twin BRCT domain fn3 PF00041.21 KIY68428.1 - 7.7e-06 26.2 0.9 3.4e-05 24.1 0.9 2.0 1 1 0 1 1 1 1 Fibronectin type III domain DUF3006 PF11213.8 KIY68428.1 - 0.0013 18.9 0.0 0.0022 18.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3006) Pkinase PF00069.25 KIY68429.1 - 7.4e-61 205.8 0.0 8.9e-61 205.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY68429.1 - 3.5e-29 101.9 0.0 6.4e-29 101.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY68429.1 - 0.00074 18.9 0.8 0.0016 17.8 0.8 1.5 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KIY68429.1 - 0.041 12.8 0.1 0.054 12.4 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 KIY68429.1 - 0.081 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Orexin_rec2 PF03827.13 KIY68429.1 - 0.17 11.9 0.3 0.4 10.7 0.1 1.6 2 0 0 2 2 2 0 Orexin receptor type 2 AAA_16 PF13191.6 KIY68430.1 - 0.041 14.3 0.0 0.14 12.5 0.0 1.9 1 1 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 KIY68430.1 - 0.18 11.7 0.0 0.56 10.1 0.0 1.8 2 0 0 2 2 2 0 NACHT domain Xan_ur_permease PF00860.20 KIY68433.1 - 3.8e-63 213.5 28.5 1e-42 146.3 12.8 2.1 2 0 0 2 2 2 2 Permease family Phage_holin_2_3 PF16080.5 KIY68433.1 - 1.6 8.5 4.1 0.83 9.5 0.3 2.5 2 0 0 2 2 2 0 Bacteriophage holin family HP1 PAC4 PF16093.5 KIY68434.1 - 2.1e-22 79.1 0.1 2.8e-22 78.7 0.1 1.2 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 FAD_binding_4 PF01565.23 KIY68435.1 - 3.4e-18 65.7 0.2 5.8e-18 65.0 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain ALO PF04030.14 KIY68435.1 - 2.6e-06 27.5 0.3 4.4e-05 23.4 0.1 2.7 2 1 0 2 2 2 1 D-arabinono-1,4-lactone oxidase FAD-oxidase_C PF02913.19 KIY68435.1 - 0.081 12.5 0.0 12 5.5 0.0 2.3 2 0 0 2 2 2 0 FAD linked oxidases, C-terminal domain FAD_binding_5 PF00941.21 KIY68435.1 - 0.14 11.9 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain in molybdopterin dehydrogenase PSCyt3 PF07627.11 KIY68436.1 - 0.1 12.9 0.4 35 4.8 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1588) Spc7 PF08317.11 KIY68438.1 - 0.00097 18.1 3.4 0.0016 17.4 3.4 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein Filament PF00038.21 KIY68438.1 - 0.0013 18.4 4.8 0.0021 17.7 4.8 1.4 1 0 0 1 1 1 1 Intermediate filament protein Exonuc_VII_L PF02601.15 KIY68438.1 - 0.0089 15.6 2.5 0.012 15.2 2.5 1.2 1 0 0 1 1 1 1 Exonuclease VII, large subunit Laminin_II PF06009.12 KIY68438.1 - 0.0095 15.9 0.4 0.021 14.9 0.3 1.6 1 1 0 1 1 1 1 Laminin Domain II DUF4200 PF13863.6 KIY68438.1 - 0.017 15.5 5.4 0.029 14.8 5.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) TACC_C PF05010.14 KIY68438.1 - 0.022 14.5 3.9 0.035 13.9 3.9 1.2 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal TPR_MLP1_2 PF07926.12 KIY68438.1 - 0.025 14.6 12.7 0.045 13.8 2.0 2.6 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Golgin_A5 PF09787.9 KIY68438.1 - 0.026 14.0 7.9 0.04 13.4 7.9 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 Cep57_CLD PF14073.6 KIY68438.1 - 0.052 13.6 7.3 0.091 12.8 7.3 1.4 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 FAM184 PF15665.5 KIY68438.1 - 0.14 11.9 9.2 0.26 11.0 9.2 1.3 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B OmpH PF03938.14 KIY68438.1 - 0.18 12.2 7.1 1.7 9.0 7.1 2.2 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) SYCE1 PF15233.6 KIY68438.1 - 0.3 11.1 8.2 0.51 10.4 8.2 1.3 1 0 0 1 1 1 0 Synaptonemal complex central element protein 1 COG6 PF06419.11 KIY68438.1 - 0.42 8.8 4.1 0.63 8.2 4.1 1.1 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 DUF4407 PF14362.6 KIY68438.1 - 0.48 9.7 7.5 0.83 9.0 7.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SPATA1_C PF15743.5 KIY68438.1 - 0.59 10.2 6.9 2.2 8.3 2.5 2.3 1 1 1 2 2 2 0 Spermatogenesis-associated C-terminus BRE1 PF08647.11 KIY68438.1 - 0.79 9.8 6.8 0.33 11.0 2.0 2.3 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase DUF3552 PF12072.8 KIY68438.1 - 2.1 7.7 9.5 3.5 7.0 9.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) HAUS6_N PF14661.6 KIY68438.1 - 3.8 7.0 7.3 7.2 6.1 7.3 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus CCDC-167 PF15188.6 KIY68438.1 - 6.4 7.2 6.8 1 9.8 1.0 2.4 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Jnk-SapK_ap_N PF09744.9 KIY68438.1 - 7.9 6.7 14.8 26 5.0 14.8 1.8 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 Cep57_CLD PF14073.6 KIY68439.1 - 0.0011 19.0 4.3 0.0017 18.4 4.3 1.2 1 0 0 1 1 1 1 Centrosome localisation domain of Cep57 PilJ PF13675.6 KIY68439.1 - 0.077 13.0 6.0 0.13 12.3 3.4 2.3 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF4407 PF14362.6 KIY68439.1 - 0.15 11.4 6.1 0.22 10.8 6.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Abhydrolase_1 PF00561.20 KIY68439.1 - 0.21 11.2 1.1 1.6 8.3 0.0 2.5 3 0 0 3 3 3 0 alpha/beta hydrolase fold Golgin_A5 PF09787.9 KIY68439.1 - 0.22 10.9 8.1 0.33 10.4 8.1 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 OmpH PF03938.14 KIY68439.1 - 0.93 9.8 13.0 5.3 7.4 13.0 2.0 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) TMPIT PF07851.13 KIY68439.1 - 0.97 8.6 3.1 1.5 8.0 3.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF4140 PF13600.6 KIY68439.1 - 3.8 8.0 7.1 21 5.6 0.4 2.6 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Fib_alpha PF08702.10 KIY68439.1 - 4.7 7.4 5.6 12 6.0 5.6 1.7 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Exonuc_VII_L PF02601.15 KIY68439.1 - 6.7 6.2 7.9 9.9 5.6 7.9 1.4 1 1 0 1 1 1 0 Exonuclease VII, large subunit FGGY_C PF02782.16 KIY68440.1 - 0.16 11.7 0.0 0.57 9.9 0.0 1.8 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain Pkinase PF00069.25 KIY68441.1 - 1.1e-55 188.9 0.0 1.7e-55 188.3 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY68441.1 - 5.2e-23 81.6 0.0 9e-23 80.9 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY68441.1 - 3.9e-08 33.0 0.0 1.2e-07 31.4 0.0 1.8 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 KIY68441.1 - 0.00021 21.3 0.0 0.00029 20.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KIY68441.1 - 0.00041 19.8 0.0 0.00073 19.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KIY68441.1 - 0.00046 19.1 0.0 0.00053 18.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 KIY68441.1 - 0.0018 18.0 0.0 0.031 13.9 0.0 2.2 1 1 1 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Pkinase_C PF00433.24 KIY68441.1 - 0.014 16.1 0.2 0.032 14.9 0.2 1.6 1 0 0 1 1 1 0 Protein kinase C terminal domain Haspin_kinase PF12330.8 KIY68441.1 - 0.045 12.7 0.0 0.06 12.3 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 KIY68441.1 - 0.12 12.0 0.0 0.29 10.7 0.0 1.6 2 0 0 2 2 2 0 RIO1 family Peptidase_M28 PF04389.17 KIY68442.1 - 1.3e-31 109.8 0.1 2.3e-31 109.1 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KIY68442.1 - 0.0085 15.8 0.0 0.02 14.6 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Pkinase PF00069.25 KIY68443.1 - 1.1e-59 202.0 0.0 2.8e-59 200.6 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY68443.1 - 2.3e-26 92.6 0.0 6.5e-26 91.2 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY68443.1 - 1.1e-11 44.6 0.0 4.3e-11 42.7 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KIY68443.1 - 3.8e-06 25.9 0.0 6.3e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KIY68443.1 - 2.5e-05 24.4 0.4 7.5e-05 22.8 0.0 2.0 3 0 0 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 KIY68443.1 - 0.00034 20.0 0.0 0.0006 19.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KIY68443.1 - 0.0028 16.7 0.0 0.0038 16.2 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 KIY68443.1 - 0.11 12.1 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 RIO1 family adh_short_C2 PF13561.6 KIY68444.1 - 1.5e-39 135.9 0.1 8.5e-39 133.5 0.1 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIY68444.1 - 3.9e-36 124.4 0.4 2e-35 122.0 0.4 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIY68444.1 - 9.6e-07 28.9 0.4 1.5e-06 28.2 0.4 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KIY68444.1 - 0.00038 20.0 0.1 0.032 13.7 0.2 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 KIY68444.1 - 0.0079 16.1 0.2 0.016 15.1 0.2 1.6 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 KIY68444.1 - 0.018 14.2 0.0 0.037 13.1 0.0 1.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein DUF2347 PF09804.9 KIY68445.1 - 2.9e-32 112.4 0.0 2e-14 53.9 0.0 3.0 1 1 1 2 2 2 2 Uncharacterized conserved protein (DUF2347) Avl9 PF09794.9 KIY68445.1 - 0.00078 18.2 0.0 1.1 7.9 0.0 2.5 2 1 1 3 3 3 2 Transport protein Avl9 HMG_box PF00505.19 KIY68446.1 - 5.3e-12 46.0 0.0 6.3e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KIY68446.1 - 0.0039 17.8 0.2 0.0081 16.7 0.2 1.6 1 1 0 1 1 1 1 HMG-box domain IBR PF01485.21 KIY68447.1 - 2.8e-13 49.9 39.3 2.4e-09 37.3 16.9 4.5 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-C3HC4_2 PF13923.6 KIY68447.1 - 0.0014 18.4 0.8 0.0014 18.4 0.8 5.1 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIY68447.1 - 0.0038 17.1 4.2 0.0038 17.1 4.2 5.0 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KIY68447.1 - 0.28 11.1 28.7 0.18 11.7 3.2 4.2 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIY68447.1 - 9.8 6.6 35.3 0.057 13.8 4.8 4.3 2 1 1 3 3 3 0 Ring finger domain ADH_zinc_N PF00107.26 KIY68450.1 - 4.3e-28 97.9 1.2 8.4e-28 96.9 1.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIY68450.1 - 6.1e-28 96.9 2.3 1.1e-27 96.1 2.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KIY68450.1 - 2.1e-05 25.6 0.6 4e-05 24.7 0.6 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Fer4_4 PF12800.7 KIY68450.1 - 1.7 9.4 5.3 2 9.1 1.4 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Asp PF00026.23 KIY68451.1 - 6.4e-69 232.8 0.9 7.7e-69 232.5 0.9 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIY68451.1 - 2.4e-12 47.5 4.5 4.4e-08 33.6 0.4 2.6 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KIY68451.1 - 0.035 14.7 3.1 0.83 10.3 1.6 3.5 2 1 1 3 3 3 0 Aspartyl protease Pkinase PF00069.25 KIY68452.1 - 4.5e-65 219.6 0.0 4.5e-65 219.6 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY68452.1 - 1.4e-29 103.2 0.0 2.1e-29 102.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY68452.1 - 1.7e-08 34.2 0.0 3.5e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KIY68452.1 - 5.6e-05 23.2 0.7 0.057 13.3 0.4 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KIY68452.1 - 0.00039 19.3 13.1 0.0064 15.3 12.6 2.3 1 1 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 KIY68452.1 - 0.00094 18.9 0.1 0.42 10.2 0.0 3.1 3 0 0 3 3 3 2 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 KIY68452.1 - 0.0013 17.8 0.0 0.0023 16.9 0.0 1.4 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KIY68452.1 - 0.013 14.8 0.6 0.19 11.1 0.6 2.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KIY68452.1 - 0.042 13.5 0.0 0.042 13.5 0.0 3.1 4 0 0 4 4 4 0 RIO1 family PSS PF03034.15 KIY68453.1 - 5.8e-116 387.0 11.0 7.4e-116 386.7 11.0 1.1 1 0 0 1 1 1 1 Phosphatidyl serine synthase PET PF06297.14 KIY68453.1 - 0.037 14.3 0.0 0.089 13.1 0.0 1.6 1 0 0 1 1 1 0 PET Domain TMEM169 PF15052.6 KIY68453.1 - 1.6 8.8 7.7 3.7 7.7 3.0 2.8 2 0 0 2 2 2 0 TMEM169 protein family DDE_Tnp_IS66_C PF13817.6 KIY68454.1 - 0.12 12.6 0.0 0.64 10.3 0.0 2.1 2 0 0 2 2 2 0 IS66 C-terminal element DUF4491 PF14898.6 KIY68455.1 - 2 8.9 6.6 16 6.0 6.6 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4491) PLDc_2 PF13091.6 KIY68459.1 - 5.8e-18 65.1 0.2 1.5e-06 28.2 0.0 3.5 3 0 0 3 3 3 3 PLD-like domain PLDc PF00614.22 KIY68459.1 - 7.9e-17 60.7 3.1 6.5e-09 35.6 0.3 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif Fungal_trans PF04082.18 KIY68460.1 - 8.1e-09 34.9 0.1 1.4e-08 34.1 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY68460.1 - 3.4e-07 30.3 11.4 3.4e-07 30.3 11.4 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Paralemmin PF03285.15 KIY68460.1 - 0.041 13.5 0.1 0.065 12.8 0.1 1.2 1 0 0 1 1 1 0 Paralemmin VCX_VCY PF15231.6 KIY68460.1 - 0.062 14.0 2.0 0.13 13.0 2.0 1.5 1 0 0 1 1 1 0 Variable charge X/Y family SPA PF08616.10 KIY68462.1 - 4.9e-34 116.7 0.0 8.7e-34 115.9 0.0 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis Afi1 PF07792.12 KIY68462.1 - 8e-16 58.7 0.2 5.1e-13 49.7 0.3 2.6 2 0 0 2 2 2 2 Docking domain of Afi1 for Arf3 in vesicle trafficking Avl9 PF09794.9 KIY68462.1 - 0.1 11.2 0.0 1.7 7.3 0.0 2.6 2 1 1 3 3 3 0 Transport protein Avl9 SLAC1 PF03595.17 KIY68463.1 - 2.5e-56 191.3 41.6 3.1e-56 191.0 41.6 1.1 1 0 0 1 1 1 1 Voltage-dependent anion channel NOG1_N PF17835.1 KIY68466.1 - 6.2e-50 169.3 0.7 6.2e-50 169.3 0.7 2.0 2 0 0 2 2 2 1 NOG1 N-terminal helical domain NOG1 PF06858.14 KIY68466.1 - 1.7e-26 91.8 0.1 3.5e-26 90.7 0.1 1.6 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) NOGCT PF08155.11 KIY68466.1 - 6.3e-26 90.1 0.7 6.3e-26 90.1 0.7 2.2 2 0 0 2 2 1 1 NOGCT (NUC087) domain MMR_HSR1 PF01926.23 KIY68466.1 - 1.5e-16 60.5 0.0 3.7e-16 59.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KIY68466.1 - 1.9e-11 43.7 0.0 5.3e-11 42.3 0.0 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KIY68466.1 - 0.0013 18.8 0.9 1.7 8.7 0.0 2.8 2 1 1 3 3 3 2 Dynamin family RsgA_GTPase PF03193.16 KIY68466.1 - 0.0052 16.7 0.0 2.9 7.8 0.0 2.9 2 1 0 2 2 2 1 RsgA GTPase MMR_HSR1_Xtn PF16897.5 KIY68466.1 - 0.039 14.0 0.1 0.34 10.9 0.0 2.4 1 1 1 2 2 2 0 C-terminal region of MMR_HSR1 domain Sushi_2 PF09014.10 KIY68466.1 - 0.074 12.9 0.2 0.2 11.6 0.2 1.7 1 0 0 1 1 1 0 Beta-2-glycoprotein-1 fifth domain AIG1 PF04548.16 KIY68466.1 - 0.09 12.1 0.0 0.19 11.0 0.0 1.6 1 0 0 1 1 1 0 AIG1 family AAA_16 PF13191.6 KIY68466.1 - 0.093 13.1 0.0 0.88 9.9 0.0 2.5 3 0 0 3 3 3 0 AAA ATPase domain DUF4611 PF15387.6 KIY68466.1 - 9.4 6.5 12.8 15 5.8 3.6 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) MFS_1 PF07690.16 KIY68467.1 - 1.2e-20 73.7 48.9 2.5e-13 49.7 22.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pec_lyase_C PF00544.19 KIY68468.1 - 6.4e-48 163.1 6.6 9.9e-48 162.5 6.6 1.3 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 KIY68468.1 - 1.6e-05 24.8 17.3 0.0066 16.3 8.6 2.3 1 1 1 2 2 2 2 Right handed beta helix region Disaggr_assoc PF08480.10 KIY68468.1 - 0.0058 16.5 11.1 0.0066 16.3 2.3 2.7 1 1 1 2 2 2 2 Disaggregatase related Fimbrillin_C PF15495.6 KIY68468.1 - 0.033 14.6 0.0 0.088 13.3 0.0 1.7 1 0 0 1 1 1 0 Major fimbrial subunit protein type IV, Fimbrillin, C-terminal Pkinase PF00069.25 KIY68469.1 - 2.8e-62 210.5 0.0 3.8e-62 210.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY68469.1 - 9.6e-25 87.3 0.0 1.3e-24 86.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY68469.1 - 4e-08 32.9 0.0 9e-08 31.8 0.0 1.6 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 KIY68469.1 - 0.0042 16.7 0.1 1.6 8.3 0.0 2.4 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KIY68469.1 - 0.0045 16.9 0.1 0.099 12.5 0.1 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KIY68469.1 - 0.016 14.6 0.0 0.049 13.0 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cullin_binding PF03556.15 KIY68470.1 - 9.5e-31 106.7 0.0 1.5e-30 106.1 0.0 1.3 1 0 0 1 1 1 1 Cullin binding UBA_4 PF14555.6 KIY68470.1 - 4.2e-09 36.1 0.0 8.1e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain F-box-like PF12937.7 KIY68471.1 - 0.00027 20.7 0.4 0.00087 19.1 0.4 1.9 1 0 0 1 1 1 1 F-box-like Pkinase PF00069.25 KIY68472.1 - 1e-47 162.7 0.0 1.3e-47 162.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY68472.1 - 2.3e-26 92.6 0.0 3.2e-26 92.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY68472.1 - 2e-05 24.1 0.0 3.2e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KIY68472.1 - 0.0001 21.2 0.8 0.00014 20.8 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KIY68472.1 - 0.0027 17.7 0.0 0.0046 16.9 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KIY68472.1 - 0.011 15.2 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KIY68472.1 - 0.032 13.8 0.1 0.45 10.1 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase PF00069.25 KIY68473.1 - 4.5e-52 177.0 0.0 1.4e-51 175.4 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY68473.1 - 1.2e-27 96.8 0.0 3.8e-27 95.2 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY68473.1 - 2e-07 30.7 0.0 9.9e-07 28.3 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KIY68473.1 - 3.9e-05 23.1 0.0 6.9e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIY68473.1 - 0.0012 18.9 0.1 0.002 18.1 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KIY68473.1 - 0.0078 15.8 0.0 0.019 14.6 0.0 1.6 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 KIY68473.1 - 0.0094 14.9 0.0 0.014 14.3 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KIY68473.1 - 0.05 12.4 0.4 0.2 10.4 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase NAD_binding_10 PF13460.6 KIY68474.1 - 6.9e-25 88.0 0.7 1.1e-24 87.3 0.7 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KIY68474.1 - 0.0022 17.5 0.0 0.0042 16.6 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Get5_C PF18514.1 KIY68474.1 - 0.22 11.3 1.3 21 4.9 0.1 3.3 3 0 0 3 3 3 0 Get5 C-terminal domain Aminotran_3 PF00202.21 KIY68475.1 - 6e-116 387.4 0.0 7.5e-116 387.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III MFS_1 PF07690.16 KIY68475.1 - 1.2e-19 70.5 50.0 5.9e-16 58.3 34.3 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Aminotran_1_2 PF00155.21 KIY68475.1 - 0.0011 18.2 0.0 0.0016 17.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DUF373 PF04123.13 KIY68475.1 - 0.056 12.9 0.5 0.096 12.1 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF373) F-box PF00646.33 KIY68476.1 - 0.00016 21.4 0.4 0.00058 19.7 0.2 2.1 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KIY68476.1 - 0.00048 20.0 0.6 0.001 18.9 0.6 1.6 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KIY68476.1 - 0.0034 17.2 0.0 0.0079 16.1 0.0 1.5 1 0 0 1 1 1 1 F-box TMCO5 PF14992.6 KIY68476.1 - 0.026 14.1 0.2 0.043 13.4 0.2 1.3 1 0 0 1 1 1 0 TMCO5 family adh_short_C2 PF13561.6 KIY68477.1 - 6.9e-49 166.5 0.0 1.2e-48 165.7 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIY68477.1 - 1.6e-46 158.2 0.0 2.3e-46 157.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIY68477.1 - 1.6e-10 41.2 0.8 1.1e-09 38.4 0.1 2.0 1 1 1 2 2 2 1 KR domain Epimerase PF01370.21 KIY68477.1 - 0.0012 18.4 0.0 0.0028 17.2 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 KIY68477.1 - 0.0026 17.7 0.4 0.0052 16.7 0.4 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1776 PF08643.10 KIY68477.1 - 0.023 14.1 0.0 0.031 13.6 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Pyr_redox PF00070.27 KIY68477.1 - 0.055 14.0 1.9 0.15 12.6 0.9 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase RmlD_sub_bind PF04321.17 KIY68477.1 - 0.078 12.1 0.1 0.12 11.4 0.1 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain FTR PF01913.18 KIY68477.1 - 0.14 12.1 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 Formylmethanofuran-tetrahydromethanopterin formyltransferase Methyltransf_16 PF10294.9 KIY68478.1 - 3.2e-07 30.3 0.0 0.013 15.3 0.0 2.4 2 0 0 2 2 2 2 Lysine methyltransferase Methyltransf_23 PF13489.6 KIY68478.1 - 0.018 14.9 0.0 0.059 13.2 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain S1-P1_nuclease PF02265.16 KIY68479.1 - 8.4e-39 133.9 0.1 3.8e-34 118.6 0.0 3.0 3 0 0 3 3 3 3 S1/P1 Nuclease ChlamPMP_M PF07548.11 KIY68480.1 - 0.02 14.8 0.0 0.029 14.3 0.0 1.2 1 0 0 1 1 1 0 Chlamydia polymorphic membrane protein middle domain Acyltransferase PF01553.21 KIY68481.1 - 4.9e-15 55.3 0.0 8.9e-15 54.5 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Zn_clus PF00172.18 KIY68482.1 - 9.6e-05 22.4 5.8 0.00015 21.8 5.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KIY68483.1 - 9e-19 67.5 0.0 1.4e-18 66.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY68483.1 - 2.4e-08 34.0 7.4 4.8e-08 33.0 7.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Kinesin_assoc PF16183.5 KIY68483.1 - 0.11 12.7 0.2 0.19 11.9 0.2 1.3 1 0 0 1 1 1 0 Kinesin-associated adh_short_C2 PF13561.6 KIY68484.1 - 1.7e-51 175.1 4.2 4.8e-51 173.6 4.2 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIY68484.1 - 1.2e-38 132.5 2.8 3.1e-38 131.2 2.8 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIY68484.1 - 4.1e-08 33.3 2.1 3.9e-06 26.9 2.3 2.8 2 1 0 2 2 2 1 KR domain Aldedh PF00171.22 KIY68485.1 - 5.1e-124 414.3 0.1 6.1e-124 414.0 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family SHE3 PF17078.5 KIY68486.1 - 0.0013 18.5 5.2 0.0013 18.5 5.2 5.6 4 2 1 5 5 5 2 SWI5-dependent HO expression protein 3 Spc7 PF08317.11 KIY68486.1 - 0.0022 16.9 15.7 0.0022 16.9 15.7 5.4 2 1 4 6 6 6 4 Spc7 kinetochore protein TMF_DNA_bd PF12329.8 KIY68486.1 - 0.0056 16.7 75.6 0.069 13.2 1.0 9.8 3 2 7 10 10 10 7 TATA element modulatory factor 1 DNA binding DUF4201 PF13870.6 KIY68486.1 - 0.0085 15.8 9.0 0.0085 15.8 9.0 6.6 4 2 3 7 7 7 2 Domain of unknown function (DUF4201) Fez1 PF06818.15 KIY68486.1 - 0.066 13.7 78.4 0.36 11.3 9.6 5.4 2 2 3 5 5 5 0 Fez1 Abhydrolase_6 PF12697.7 KIY68488.1 - 7.4e-13 49.6 3.7 8.9e-13 49.3 3.7 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIY68488.1 - 4.5e-06 26.1 0.0 5.1e-06 25.9 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 HMGL-like PF00682.19 KIY68489.1 - 5.7e-50 170.3 0.0 6.6e-50 170.1 0.0 1.0 1 0 0 1 1 1 1 HMGL-like PDEase_I PF00233.19 KIY68490.1 - 9.7e-54 182.6 0.1 1.6e-53 181.9 0.1 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.22 KIY68490.1 - 0.023 14.9 0.0 0.04 14.1 0.0 1.4 1 0 0 1 1 1 0 HD domain F-box-like PF12937.7 KIY68491.1 - 1.9e-05 24.5 1.0 5.2e-05 23.0 1.0 1.8 1 0 0 1 1 1 1 F-box-like DUF1731 PF08338.11 KIY68491.1 - 0.14 12.0 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1731) Sugar_tr PF00083.24 KIY68494.1 - 9e-116 387.4 29.1 1e-115 387.2 29.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY68494.1 - 2.9e-21 75.8 37.6 1.3e-18 67.1 26.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily SLATT_1 PF18181.1 KIY68496.1 - 2.4 8.1 4.7 0.92 9.4 1.2 2.0 2 1 1 3 3 3 0 SMODS and SLOG-associating 2TM effector domain 1 Glyco_hydro_7 PF00840.20 KIY68497.1 - 3.4e-206 685.1 16.2 4e-206 684.9 16.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 CBM_1 PF00734.18 KIY68497.1 - 1e-10 41.4 7.2 1e-10 41.4 7.2 3.9 4 1 0 4 4 4 1 Fungal cellulose binding domain O-FucT PF10250.9 KIY68498.1 - 3.3e-14 53.3 0.0 1.2e-13 51.4 0.0 2.0 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Abhydrolase_6 PF12697.7 KIY68499.1 - 1.7e-09 38.6 1.3 3.1e-09 37.8 1.3 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIY68499.1 - 3.8e-08 32.9 0.2 1.2e-06 28.0 0.0 2.1 1 1 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KIY68499.1 - 1.2e-06 28.4 0.2 8.7e-05 22.3 0.0 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold DUF1749 PF08538.10 KIY68499.1 - 5.6e-06 25.7 0.0 9.1e-06 25.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Peptidase_S9 PF00326.21 KIY68499.1 - 1.7e-05 24.4 0.1 5.9e-05 22.6 0.1 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family DUF915 PF06028.11 KIY68499.1 - 0.012 15.0 0.0 0.02 14.2 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_2 PF02230.16 KIY68499.1 - 0.015 15.1 0.0 0.46 10.2 0.0 2.4 2 1 1 3 3 3 0 Phospholipase/Carboxylesterase Patatin PF01734.22 KIY68499.1 - 0.015 15.5 0.0 0.018 15.3 0.0 1.2 1 0 0 1 1 1 0 Patatin-like phospholipase Esterase PF00756.20 KIY68499.1 - 0.12 12.0 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Putative esterase DUF1057 PF06342.12 KIY68499.1 - 0.17 10.9 0.0 0.26 10.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) zf-MYND PF01753.18 KIY68500.1 - 6.5e-05 22.9 7.9 0.00011 22.2 7.9 1.4 1 0 0 1 1 1 1 MYND finger BCDHK_Adom3 PF10436.9 KIY68502.1 - 8.3e-65 217.6 0.0 1.5e-64 216.7 0.0 1.4 1 1 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KIY68502.1 - 2e-13 50.8 0.0 4.1e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KIY68502.1 - 0.0013 18.6 0.0 0.0027 17.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase BTB PF00651.31 KIY68503.1 - 0.01 16.0 0.0 0.015 15.5 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain Apolipo_F PF15148.6 KIY68503.1 - 0.025 14.1 0.0 0.072 12.6 0.0 1.7 2 0 0 2 2 2 0 Apolipoprotein F F-box-like PF12937.7 KIY68506.1 - 0.00078 19.3 0.4 0.0017 18.2 0.4 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY68506.1 - 0.013 15.4 0.2 0.034 14.0 0.2 1.7 1 0 0 1 1 1 0 F-box domain M16C_assoc PF08367.11 KIY68507.1 - 0.0081 15.3 0.0 0.099 11.8 0.0 2.5 3 0 0 3 3 3 1 Peptidase M16C associated PAR1 PF06521.11 KIY68507.1 - 0.26 10.9 5.5 0.34 10.5 0.5 2.7 1 1 2 3 3 3 0 PAR1 protein F-box PF00646.33 KIY68509.1 - 0.063 13.2 0.1 0.15 12.0 0.1 1.6 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 KIY68509.1 - 0.097 12.6 0.1 0.18 11.7 0.1 1.4 1 0 0 1 1 1 0 F-box-like Filament PF00038.21 KIY68512.1 - 0.00066 19.4 25.3 0.00066 19.4 25.3 2.1 2 0 0 2 2 2 1 Intermediate filament protein Na_Ca_ex PF01699.24 KIY68513.1 - 5.6e-14 52.4 23.1 2.1e-07 31.0 10.3 3.1 2 1 1 3 3 3 3 Sodium/calcium exchanger protein DUF3981 PF13139.6 KIY68513.1 - 0.59 10.5 4.4 2.2 8.7 1.3 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3981) Pox_I5 PF04713.12 KIY68513.1 - 0.8 9.8 8.4 2.6 8.2 0.7 4.0 4 0 0 4 4 4 0 Poxvirus protein I5 DUF667 PF05018.13 KIY68515.1 - 4.6e-17 62.3 0.0 6.3e-09 35.8 0.0 3.1 2 1 0 2 2 2 2 Protein of unknown function (DUF667) F-box-like PF12937.7 KIY68516.1 - 0.00077 19.3 0.2 0.0023 17.8 0.2 1.9 1 0 0 1 1 1 1 F-box-like DUF4614 PF15391.6 KIY68517.1 - 0.62 10.0 5.9 1.3 9.0 5.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Herpes_capsid PF06112.11 KIY68517.1 - 1.1 9.3 11.3 1.8 8.6 11.3 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein F-box PF00646.33 KIY68518.1 - 0.01 15.7 1.0 0.053 13.4 0.4 2.2 2 0 0 2 2 2 0 F-box domain M16C_assoc PF08367.11 KIY68519.1 - 0.0097 15.1 0.0 0.099 11.8 0.0 2.4 3 0 0 3 3 3 1 Peptidase M16C associated PAR1 PF06521.11 KIY68519.1 - 0.026 14.2 2.5 0.076 12.6 0.4 2.2 1 1 1 2 2 2 0 PAR1 protein GTP-bdg_N PF13167.6 KIY68519.1 - 0.081 13.6 0.0 0.37 11.5 0.0 2.1 1 1 2 3 3 3 0 GTP-binding GTPase N-terminal Trp_oprn_chp PF09534.10 KIY68520.1 - 0.0039 17.0 0.1 0.005 16.6 0.1 1.3 1 0 0 1 1 1 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) SfLAP PF11139.8 KIY68520.1 - 0.025 14.0 0.1 0.036 13.5 0.1 1.2 1 0 0 1 1 1 0 Sap, sulfolipid-1-addressing protein Herpes_gE PF02480.16 KIY68520.1 - 0.028 13.2 0.1 0.074 11.8 0.0 1.6 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E LapA_dom PF06305.11 KIY68520.1 - 0.054 13.3 0.5 0.082 12.7 0.5 1.2 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF4381 PF14316.6 KIY68520.1 - 0.061 13.6 0.1 0.094 13.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) AJAP1_PANP_C PF15298.6 KIY68520.1 - 0.08 13.1 0.4 0.08 13.1 0.4 2.1 1 1 1 2 2 2 0 AJAP1/PANP C-terminus m04gp34like PF12216.8 KIY68520.1 - 0.093 12.3 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Immune evasion protein OAD_gamma PF04277.13 KIY68520.1 - 0.1 13.2 1.6 0.14 12.7 0.1 2.1 2 1 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain IgaA PF07095.11 KIY68520.1 - 0.15 10.0 0.0 0.19 9.7 0.0 1.0 1 0 0 1 1 1 0 Intracellular growth attenuator protein IgaA EphA2_TM PF14575.6 KIY68520.1 - 0.16 12.8 0.0 0.22 12.4 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain CD34_antigen PF06365.12 KIY68520.1 - 0.24 10.9 0.0 0.37 10.3 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family TMEM100 PF16311.5 KIY68520.1 - 0.27 10.8 2.0 0.41 10.2 1.2 1.7 1 1 1 2 2 2 0 Transmembrane protein 100 TMEM51 PF15345.6 KIY68520.1 - 7.6 6.3 9.3 0.87 9.4 0.2 2.3 1 1 1 2 2 2 0 Transmembrane protein 51 Trp_oprn_chp PF09534.10 KIY68522.1 - 0.001 18.9 0.0 0.0013 18.5 0.0 1.3 1 0 0 1 1 1 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) TMEM51 PF15345.6 KIY68522.1 - 0.018 14.9 1.3 0.26 11.1 0.0 2.2 2 0 0 2 2 2 0 Transmembrane protein 51 EphA2_TM PF14575.6 KIY68522.1 - 0.049 14.5 0.0 0.13 13.2 0.0 1.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Herpes_gE PF02480.16 KIY68522.1 - 0.05 12.4 1.0 0.17 10.6 0.1 1.9 1 1 0 2 2 2 0 Alphaherpesvirus glycoprotein E DUF4381 PF14316.6 KIY68522.1 - 0.061 13.6 0.0 0.096 12.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) IgaA PF07095.11 KIY68522.1 - 0.24 9.3 0.0 0.3 9.0 0.0 1.1 1 0 0 1 1 1 0 Intracellular growth attenuator protein IgaA Adeno_E3_CR2 PF02439.15 KIY68522.1 - 0.6 9.9 5.5 1.3 8.8 5.5 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 AJAP1_PANP_C PF15298.6 KIY68522.1 - 1.6 8.9 7.1 0.24 11.6 1.3 2.0 1 1 1 2 2 2 0 AJAP1/PANP C-terminus LapA_dom PF06305.11 KIY68522.1 - 4.5 7.2 4.6 0.46 10.3 0.2 1.5 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Rbsn PF11464.8 KIY68523.1 - 0.13 12.1 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 Rabenosyn Rab binding domain KKLCAg1 PF15204.6 KIY68523.1 - 0.72 10.0 3.4 1.7 8.8 3.4 1.6 1 1 0 1 1 1 0 Kita-kyushu lung cancer antigen 1 adh_short PF00106.25 KIY68525.1 - 2.3e-38 131.7 1.8 4.3e-38 130.7 1.8 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIY68525.1 - 1.6e-29 103.1 0.1 2.3e-29 102.6 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIY68525.1 - 6.3e-08 32.7 1.4 7.6e-08 32.5 0.2 1.6 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KIY68525.1 - 0.0011 18.5 1.3 0.0027 17.2 1.3 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KIY68525.1 - 0.0047 16.8 0.5 0.0083 16.0 0.5 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KIY68525.1 - 0.02 14.4 0.5 0.03 13.9 0.5 1.2 1 0 0 1 1 1 0 NmrA-like family Glyco_transf_28 PF03033.20 KIY68525.1 - 0.17 11.9 0.1 0.36 10.9 0.0 1.6 2 0 0 2 2 2 0 Glycosyltransferase family 28 N-terminal domain Pyr_redox_2 PF07992.14 KIY68526.1 - 1.1e-30 106.9 0.2 1.7e-30 106.3 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIY68526.1 - 1.5e-09 38.3 1.1 5.4e-07 30.1 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KIY68526.1 - 3.5e-06 27.1 0.2 0.15 12.0 0.0 3.3 3 0 0 3 3 3 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KIY68526.1 - 0.0049 16.0 0.0 6.6 5.7 0.0 3.2 2 1 1 3 3 3 2 Lycopene cyclase protein DAO PF01266.24 KIY68526.1 - 0.092 12.3 5.8 3.7 7.0 0.5 3.0 2 1 1 3 3 3 0 FAD dependent oxidoreductase K_oxygenase PF13434.6 KIY68526.1 - 0.11 11.6 0.0 3.1 6.9 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.22 KIY68526.1 - 0.2 10.7 9.8 0.84 8.6 0.0 4.0 5 0 0 5 5 5 0 Glucose inhibited division protein A Aldo_ket_red PF00248.21 KIY68527.1 - 1.1e-42 146.3 0.0 5.3e-41 140.7 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family SET PF00856.28 KIY68528.1 - 0.0075 16.7 0.0 0.013 15.9 0.0 1.4 1 0 0 1 1 1 1 SET domain Abhydrolase_1 PF00561.20 KIY68529.1 - 7.2e-15 55.3 0.0 8.7e-15 55.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIY68529.1 - 6.7e-13 49.7 0.0 8.5e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIY68529.1 - 4.7e-09 35.9 0.0 9.3e-09 34.9 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 KIY68529.1 - 0.0022 17.7 0.0 0.0029 17.3 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.16 KIY68529.1 - 0.075 12.8 0.0 2.9 7.6 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Tenui_PVC2 PF06656.11 KIY68530.1 - 0.12 10.3 0.0 0.16 9.8 0.0 1.1 1 0 0 1 1 1 0 Tenuivirus PVC2 protein COesterase PF00135.28 KIY68532.1 - 0.0006 18.8 0.0 0.0006 18.8 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Herpes_capsid PF06112.11 KIY68533.1 - 3.3 7.8 23.5 5.2 7.1 23.5 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein HMG_box PF00505.19 KIY68534.1 - 0.0037 17.6 1.2 0.0062 16.9 1.2 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box Ccdc124 PF06244.12 KIY68534.1 - 0.036 14.6 2.0 0.036 14.6 2.0 1.4 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 124 /Oxs1 zf-MYND PF01753.18 KIY68535.1 - 7.6e-05 22.7 18.1 0.00018 21.5 18.1 1.6 1 0 0 1 1 1 1 MYND finger DUF3681 PF12442.8 KIY68535.1 - 0.09 13.2 0.0 0.29 11.6 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3681) Peptidase_M64 PF09471.10 KIY68537.1 - 0.05 13.2 0.5 0.17 11.4 0.1 1.8 1 1 1 2 2 2 0 IgA Peptidase M64 Reprolysin_4 PF13583.6 KIY68537.1 - 0.13 11.9 0.1 0.21 11.2 0.1 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like PS_Dcarbxylase PF02666.15 KIY68538.1 - 1e-54 185.1 0.0 1.7e-54 184.4 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 KIY68538.1 - 1.7e-36 124.6 0.0 1.1e-19 70.6 0.0 2.5 2 0 0 2 2 2 2 C2 domain EF-hand_6 PF13405.6 KIY68538.1 - 0.15 12.1 0.2 0.56 10.3 0.0 2.1 2 0 0 2 2 2 0 EF-hand domain Ras PF00071.22 KIY68540.1 - 6.2e-51 172.2 0.0 7.4e-51 172.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIY68540.1 - 3.3e-29 101.5 0.0 4.6e-29 101.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIY68540.1 - 2.4e-11 43.4 0.0 3.7e-11 42.8 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KIY68540.1 - 1.3e-05 25.2 0.0 3.6e-05 23.8 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KIY68540.1 - 0.00012 21.7 0.0 0.00098 18.7 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain HNH_2 PF13391.6 KIY68543.1 - 0.0064 16.6 0.0 0.012 15.8 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease Tyrosinase PF00264.20 KIY68544.1 - 1.7e-48 165.8 1.7 1.8e-48 165.8 0.1 1.8 2 0 0 2 2 2 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 KIY68544.1 - 3.4e-30 105.2 0.0 5.6e-30 104.5 0.0 1.4 1 0 0 1 1 1 1 Tyosinase C-terminal domain Glyco_transf_15 PF01793.16 KIY68545.1 - 1.6e-119 398.9 2.4 2.3e-119 398.5 2.4 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase RRM_1 PF00076.22 KIY68547.1 - 6.3e-42 141.2 0.0 1.3e-20 72.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KIY68547.1 - 2.1e-05 24.5 0.0 0.082 13.0 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 KIY68547.1 - 0.0011 18.9 0.0 0.72 9.9 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif SET_assoc PF11767.8 KIY68547.1 - 0.024 14.3 0.0 1.1 9.0 0.0 2.3 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated Tyrosinase PF00264.20 KIY68548.1 - 1.1e-19 71.7 0.4 1.5e-19 71.2 0.4 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase HTH_33 PF13592.6 KIY68549.1 - 0.00059 19.4 0.0 0.00084 18.9 0.0 1.2 1 0 0 1 1 1 1 Winged helix-turn helix DDE_3 PF13358.6 KIY68550.1 - 5.6e-08 32.7 0.0 6.2e-08 32.5 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KIY68551.1 - 1.7e-08 34.3 0.0 2.3e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF2624 PF11116.8 KIY68551.1 - 0.22 12.4 0.0 0.26 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2624) Darcynin PF17074.5 KIY68552.1 - 0.18 12.1 0.2 0.36 11.0 0.2 1.4 1 0 0 1 1 1 0 Darcynin, domain of unknown function Rep_1 PF01446.17 KIY68554.1 - 0.11 12.0 0.2 0.13 11.7 0.2 1.0 1 0 0 1 1 1 0 Replication protein DUF3961 PF13106.6 KIY68555.1 - 0.11 12.2 0.0 12 5.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3961) PknH_C PF14032.6 KIY68556.1 - 0.041 13.7 0.2 0.041 13.7 0.2 1.1 1 0 0 1 1 1 0 PknH-like extracellular domain Zn_clus PF00172.18 KIY68561.1 - 7.8e-09 35.5 7.2 2e-08 34.2 7.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain His_Me_b4a2 PF18275.1 KIY68563.1 - 0.11 12.5 0.9 0.24 11.5 0.9 1.5 1 0 0 1 1 1 0 His-Me finger endonuclease beta4-alpha2 domain zf-C2H2 PF00096.26 KIY68563.1 - 9.3 6.9 7.9 4.3 8.0 0.6 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2 PF00096.26 KIY68564.1 - 0.00019 21.7 3.5 0.00022 21.5 0.5 2.4 2 1 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIY68564.1 - 0.0055 17.4 2.2 0.011 16.6 0.3 2.2 2 0 0 2 2 2 1 C2H2-type zinc finger DUF4380 PF14315.6 KIY68564.1 - 0.0065 15.4 0.1 0.0074 15.2 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4380) zf-C2H2_jaz PF12171.8 KIY68564.1 - 0.018 15.3 0.2 0.043 14.1 0.2 1.6 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 KIY68564.1 - 0.033 14.6 4.8 0.089 13.3 0.8 2.4 2 0 0 2 2 2 0 Zinc-finger double domain FOXP-CC PF16159.5 KIY68564.1 - 1.4 9.6 5.5 4.7 7.9 0.5 2.4 1 1 1 2 2 2 0 FOXP coiled-coil domain HNH_2 PF13391.6 KIY68566.1 - 0.027 14.6 0.1 0.068 13.3 0.1 1.7 1 0 0 1 1 1 0 HNH endonuclease COX4 PF02936.14 KIY68567.1 - 2.8e-34 118.1 0.0 3.3e-34 117.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF1138 PF06592.13 KIY68567.1 - 0.14 12.2 0.0 0.69 10.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1138) AhpC-TSA PF00578.21 KIY68569.1 - 1.3e-27 96.2 0.0 1.7e-27 95.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KIY68569.1 - 7e-17 61.5 0.0 9.2e-17 61.1 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 KIY68569.1 - 0.089 12.9 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme Myticin-prepro PF10690.9 KIY68571.1 - 0.075 13.3 0.2 0.16 12.3 0.2 1.5 1 0 0 1 1 1 0 Myticin pre-proprotein from the mussel zf-H2C2_2 PF13465.6 KIY68572.1 - 4e-10 39.6 8.9 2.1e-06 27.9 0.5 3.9 4 0 0 4 4 4 2 Zinc-finger double domain Ogr_Delta PF04606.12 KIY68572.1 - 0.00042 20.2 1.6 0.55 10.3 0.1 2.7 1 1 2 3 3 3 2 Ogr/Delta-like zinc finger zf-C2H2 PF00096.26 KIY68572.1 - 0.00069 19.9 19.7 0.05 14.1 0.2 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type OrsD PF12013.8 KIY68572.1 - 0.29 11.6 15.2 3.3 8.2 0.3 3.0 2 1 1 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf_C2H2_ZHX PF18387.1 KIY68572.1 - 1.4 8.7 14.2 0.88 9.3 0.3 3.1 1 1 2 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_4 PF13894.6 KIY68572.1 - 2.1 9.4 16.7 9.3 7.4 2.8 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger p450 PF00067.22 KIY68574.1 - 2.8e-61 207.7 0.0 5.6e-61 206.7 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Sporozoite_P67 PF05642.11 KIY68575.1 - 0.065 11.3 2.0 0.077 11.1 2.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen GATA PF00320.27 KIY68576.1 - 2.6e-16 58.9 3.4 5.7e-16 57.8 3.4 1.6 1 0 0 1 1 1 1 GATA zinc finger ArfGap PF01412.18 KIY68576.1 - 0.0031 17.6 0.0 0.0058 16.7 0.0 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf TF_Zn_Ribbon PF08271.12 KIY68576.1 - 0.0071 15.8 0.7 0.0071 15.8 0.7 1.8 2 0 0 2 2 2 1 TFIIB zinc-binding DUF1192 PF06698.11 KIY68576.1 - 0.088 12.9 0.4 0.58 10.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) DUF1480 PF07351.13 KIY68577.1 - 0.1 12.9 0.0 4.4 7.6 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1480) zf-MYND PF01753.18 KIY68581.1 - 0.032 14.3 5.4 0.049 13.7 5.4 1.3 1 0 0 1 1 1 0 MYND finger Bacillus_PapR PF05968.11 KIY68582.1 - 0.016 15.1 0.1 0.033 14.0 0.1 1.5 1 0 0 1 1 1 0 Bacillus PapR protein zf-MYND PF01753.18 KIY68583.1 - 9.1e-07 28.9 13.9 1.6e-06 28.0 13.9 1.4 1 0 0 1 1 1 1 MYND finger TBK1_ULD PF18396.1 KIY68586.1 - 0.011 15.7 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain DUF4803 PF16061.5 KIY68586.1 - 0.12 11.8 0.1 0.19 11.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4803) PsbP PF01789.16 KIY68587.1 - 0.02 15.0 0.1 0.035 14.2 0.1 1.3 1 0 0 1 1 1 0 PsbP zf-RING_5 PF14634.6 KIY68589.1 - 0.0018 18.2 9.0 0.0073 16.2 9.0 1.9 1 1 0 1 1 1 1 zinc-RING finger domain zf-H2C2_2 PF13465.6 KIY68589.1 - 0.027 14.9 4.6 0.47 11.0 0.2 2.5 2 0 0 2 2 2 0 Zinc-finger double domain zf-C3HC4_2 PF13923.6 KIY68589.1 - 0.027 14.3 3.9 0.027 14.3 3.9 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Hamartin PF04388.12 KIY68589.1 - 0.11 11.1 0.2 0.12 11.0 0.2 1.1 1 0 0 1 1 1 0 Hamartin protein ADP_PFK_GK PF04587.15 KIY68589.1 - 0.12 11.0 0.1 0.15 10.6 0.1 1.1 1 0 0 1 1 1 0 ADP-specific Phosphofructokinase/Glucokinase conserved region zf-ANAPC11 PF12861.7 KIY68589.1 - 0.22 11.6 7.4 0.047 13.7 2.9 2.0 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-CHY PF05495.12 KIY68589.1 - 0.26 11.8 5.8 0.43 11.1 5.8 1.3 1 0 0 1 1 1 0 CHY zinc finger TerY_C PF15616.6 KIY68589.1 - 0.35 11.0 3.3 0.24 11.5 0.7 1.9 1 1 1 2 2 2 0 TerY-C metal binding domain DZR PF12773.7 KIY68589.1 - 0.45 10.6 6.4 11 6.2 6.9 2.3 1 1 1 2 2 2 0 Double zinc ribbon zf-ribbon_3 PF13248.6 KIY68589.1 - 0.55 9.7 0.1 0.55 9.7 0.1 3.0 4 0 0 4 4 4 0 zinc-ribbon domain Zn_Tnp_IS91 PF14319.6 KIY68589.1 - 0.91 9.6 6.2 0.35 10.9 1.6 2.1 1 1 1 2 2 2 0 Transposase zinc-binding domain zf-RING_2 PF13639.6 KIY68589.1 - 1.6 9.1 10.6 6.5 7.2 10.7 2.0 1 1 1 2 2 2 0 Ring finger domain zf-ACC PF17848.1 KIY68589.1 - 2.8 8.1 6.0 14 5.9 0.1 2.9 3 0 0 3 3 3 0 Acetyl-coA carboxylase zinc finger domain zf-C3HC4 PF00097.25 KIY68589.1 - 5.1 7.1 13.0 33 4.4 13.0 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 KIY68589.1 - 6 6.8 8.9 21 5.1 8.9 2.0 1 1 0 1 1 1 0 PHD-finger Hexapep PF00132.24 KIY68593.1 - 5e-10 38.7 16.9 4e-05 23.2 3.8 3.8 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) W2 PF02020.18 KIY68593.1 - 1.2e-09 38.2 0.0 1.2e-09 38.2 0.0 3.0 2 1 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon NTP_transferase PF00483.23 KIY68593.1 - 8.4e-08 32.1 0.0 1.3e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep_2 PF14602.6 KIY68593.1 - 8.5e-05 22.2 14.5 0.0011 18.7 3.3 3.5 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase NTP_transf_3 PF12804.7 KIY68593.1 - 9.5e-05 22.8 0.0 0.00016 22.0 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain DUF4954 PF16314.5 KIY68593.1 - 0.00031 19.0 1.0 0.0006 18.1 1.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) Fucokinase PF07959.12 KIY68593.1 - 0.00047 19.2 0.6 0.00074 18.6 0.6 1.2 1 0 0 1 1 1 1 L-fucokinase Ist1 PF03398.14 KIY68595.1 - 2.9e-37 128.1 0.0 4.5e-37 127.5 0.0 1.3 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway RabGAP-TBC PF00566.18 KIY68595.1 - 7.8e-11 42.0 0.1 1.6e-09 37.7 0.0 2.2 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Methyltransf_31 PF13847.6 KIY68596.1 - 0.0031 17.3 0.0 0.0061 16.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIY68596.1 - 0.0036 18.0 0.0 0.0071 17.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIY68596.1 - 0.023 15.4 0.0 0.04 14.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 KIY68596.1 - 0.21 10.8 0.0 0.31 10.2 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Methyltransf_16 PF10294.9 KIY68598.1 - 8.3e-23 81.0 0.0 1.1e-22 80.6 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 KIY68598.1 - 0.0079 16.0 0.0 0.011 15.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KIY68598.1 - 0.053 13.1 0.0 0.072 12.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain RhoGEF PF00621.20 KIY68599.1 - 1e-18 68.3 0.0 4e-14 53.3 0.0 2.3 2 0 0 2 2 2 2 RhoGEF domain CitMHS PF03600.16 KIY68600.1 - 0.037 13.2 0.1 0.037 13.2 0.1 1.4 2 0 0 2 2 2 0 Citrate transporter WBP-1 PF11669.8 KIY68600.1 - 0.88 10.2 0.0 0.88 10.2 0.0 2.5 3 0 0 3 3 3 0 WW domain-binding protein 1 Lyase_1 PF00206.20 KIY68601.1 - 3e-92 309.4 0.0 1.6e-91 307.0 0.0 1.8 2 0 0 2 2 2 1 Lyase ASL_C2 PF14698.6 KIY68601.1 - 2.8e-24 85.7 0.1 6.6e-24 84.5 0.1 1.7 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal Syntaxin PF00804.25 KIY68602.1 - 2.2e-34 118.9 7.4 3.1e-34 118.4 7.4 1.2 1 0 0 1 1 1 1 Syntaxin SNARE PF05739.19 KIY68602.1 - 3.3e-08 33.4 0.2 9.1e-08 32.0 0.2 1.9 1 0 0 1 1 1 1 SNARE domain Syntaxin_2 PF14523.6 KIY68602.1 - 6.6e-07 29.6 7.4 1.6e-06 28.4 4.1 2.2 2 0 0 2 2 2 1 Syntaxin-like protein VitD-bind_III PF09164.10 KIY68602.1 - 0.0096 15.9 0.1 0.024 14.6 0.1 1.6 1 0 0 1 1 1 1 Vitamin D binding protein, domain III DUF4988 PF16378.5 KIY68602.1 - 0.011 15.5 2.0 3.8 7.2 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function Tweety PF04906.13 KIY68602.1 - 0.023 13.4 0.9 0.48 9.0 0.1 2.2 2 0 0 2 2 2 0 Tweety DUF2939 PF11159.8 KIY68602.1 - 0.03 14.8 2.5 0.064 13.7 1.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2939) MCPsignal PF00015.21 KIY68602.1 - 0.032 14.1 1.1 0.032 14.1 1.1 2.3 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DASH_Dam1 PF08653.10 KIY68602.1 - 0.078 12.8 0.5 0.41 10.5 0.1 2.2 2 0 0 2 2 2 0 DASH complex subunit Dam1 Vac_Fusion PF02346.16 KIY68602.1 - 0.24 11.1 1.6 1.5 8.5 0.1 2.7 3 0 0 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 Spectrin PF00435.21 KIY68602.1 - 0.45 11.0 6.6 4.8 7.7 0.1 2.8 3 0 0 3 3 3 0 Spectrin repeat SKA1 PF07160.12 KIY68602.1 - 0.85 9.4 7.8 0.81 9.5 0.5 2.7 1 1 0 2 2 2 0 Spindle and kinetochore-associated protein 1 CdvA PF18822.1 KIY68602.1 - 6.8 6.5 10.5 3.9 7.3 0.2 3.6 3 1 0 3 3 3 0 CdvA-like coiled-coil domain Tropomyosin_1 PF12718.7 KIY68602.1 - 9.4 6.4 10.7 47 4.1 1.3 2.4 1 1 1 2 2 2 0 Tropomyosin like zf-AN1 PF01428.16 KIY68603.1 - 2.7e-10 40.2 8.1 2.7e-10 40.2 8.1 1.7 1 1 0 1 1 1 1 AN1-like Zinc finger IBR PF01485.21 KIY68603.1 - 0.064 13.5 9.8 0.076 13.2 9.1 1.5 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain DUF971 PF06155.12 KIY68603.1 - 0.1 13.3 1.8 0.13 12.9 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF971) Aminotran_1_2 PF00155.21 KIY68604.1 - 3.1e-85 286.5 0.0 3.5e-85 286.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Phos_pyr_kin PF08543.12 KIY68605.1 - 1.4e-81 273.5 0.0 6.3e-80 268.1 0.0 2.2 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.16 KIY68605.1 - 7.1e-42 143.6 0.1 1e-41 143.1 0.1 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.24 KIY68605.1 - 0.00023 20.6 0.0 0.074 12.3 0.0 2.3 2 0 0 2 2 2 2 pfkB family carbohydrate kinase HK PF02110.15 KIY68605.1 - 0.82 9.0 2.6 2.1 7.7 0.0 2.5 3 0 0 3 3 3 0 Hydroxyethylthiazole kinase family RNA_polI_A34 PF08208.11 KIY68606.1 - 5.9e-26 91.8 9.8 5.9e-26 91.8 9.8 1.8 2 0 0 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 MFS_1 PF07690.16 KIY68607.1 - 1.1e-19 70.6 19.6 1.8e-19 69.9 19.6 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Nodulin-like PF06813.13 KIY68607.1 - 8.5e-18 64.7 4.2 8.5e-18 64.7 4.2 2.1 2 0 0 2 2 2 1 Nodulin-like NFACT-R_1 PF05670.13 KIY68608.1 - 1.8e-40 137.9 0.0 2.9e-40 137.3 0.0 1.3 1 0 0 1 1 1 1 NFACT protein RNA binding domain CE2_N PF17996.1 KIY68608.1 - 0.09 12.8 0.6 1.5 8.8 0.4 2.2 2 0 0 2 2 2 0 Carbohydrate esterase 2 N-terminal Aminotran_5 PF00266.19 KIY68609.1 - 1e-33 116.9 0.0 1.4e-33 116.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V PAC2 PF09754.9 KIY68609.1 - 0.038 14.0 0.0 0.23 11.4 0.0 2.0 2 0 0 2 2 2 0 PAC2 family IMUP PF15761.5 KIY68610.1 - 0.0091 16.7 1.8 0.0091 16.7 1.8 1.7 2 0 0 2 2 2 1 Immortalisation up-regulated protein ANAPC_CDC26 PF10471.9 KIY68610.1 - 0.024 15.5 0.3 0.024 15.5 0.3 1.7 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 DUF755 PF05501.11 KIY68610.1 - 6 7.2 12.1 0.14 12.4 4.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF755) HSP90 PF00183.18 KIY68611.1 - 5.8e-227 754.7 23.4 7.1e-227 754.4 23.4 1.0 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 KIY68611.1 - 3.4e-13 50.1 0.1 6.3e-13 49.2 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KIY68611.1 - 6.6e-11 42.2 0.1 1.9e-10 40.7 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SlyX PF04102.12 KIY68612.1 - 0.0044 17.6 2.3 0.0044 17.6 2.3 6.0 4 1 2 6 6 6 1 SlyX DHR10 PF18595.1 KIY68612.1 - 0.0074 16.3 4.7 0.0074 16.3 4.7 3.4 2 1 1 3 3 3 1 Designed helical repeat protein 10 domain Phage_int_SAM_1 PF02899.17 KIY68612.1 - 0.02 15.2 12.7 0.021 15.1 1.0 4.2 4 0 0 4 4 3 0 Phage integrase, N-terminal SAM-like domain TMPIT PF07851.13 KIY68612.1 - 0.035 13.4 15.3 0.51 9.5 6.1 2.3 2 0 0 2 2 2 0 TMPIT-like protein FUSC-like PF12805.7 KIY68612.1 - 0.088 11.9 9.5 0.083 12.0 2.7 3.2 3 0 0 3 3 3 0 FUSC-like inner membrane protein yccS Filament PF00038.21 KIY68612.1 - 0.17 11.5 23.8 0.13 11.8 9.3 2.7 1 1 0 2 2 2 0 Intermediate filament protein ATG16 PF08614.11 KIY68612.1 - 0.24 11.6 31.6 0.18 12.0 8.6 3.3 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) DUF641 PF04859.12 KIY68612.1 - 0.36 11.2 19.4 0.24 11.7 2.9 3.9 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) Occludin_ELL PF07303.13 KIY68612.1 - 0.38 11.5 16.9 5 7.9 0.7 3.7 2 1 2 4 4 4 0 Occludin homology domain Noelin-1 PF12308.8 KIY68612.1 - 0.7 9.9 5.2 0.37 10.8 0.3 2.8 2 0 0 2 2 2 0 Neurogenesis glycoprotein Fib_alpha PF08702.10 KIY68612.1 - 0.8 9.9 17.5 0.52 10.5 6.9 3.0 3 0 0 3 3 2 0 Fibrinogen alpha/beta chain family Trimer_CC PF08954.11 KIY68612.1 - 1 9.0 11.2 20 4.8 0.1 4.2 4 0 0 4 4 4 0 Trimerisation motif DUF724 PF05266.14 KIY68612.1 - 2.2 8.1 18.6 0.46 10.3 4.0 2.9 3 0 0 3 3 2 0 Protein of unknown function (DUF724) Spc7 PF08317.11 KIY68612.1 - 2.2 7.1 24.6 1.6 7.5 13.0 2.7 1 1 1 2 2 2 0 Spc7 kinetochore protein ADIP PF11559.8 KIY68612.1 - 2.7 8.1 23.4 3.4 7.7 2.4 3.9 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Uso1_p115_C PF04871.13 KIY68612.1 - 3.3 8.1 27.2 1.1 9.6 4.8 3.2 3 0 0 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region Laminin_II PF06009.12 KIY68612.1 - 3.7 7.6 10.1 6 6.9 0.2 3.1 1 1 0 2 2 2 0 Laminin Domain II Lzipper-MIP1 PF14389.6 KIY68612.1 - 4 7.8 12.4 1.1 9.6 3.4 3.6 3 0 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 Golgin_A5 PF09787.9 KIY68612.1 - 6.3 6.2 26.7 3.1 7.2 6.1 2.6 1 1 0 2 2 2 0 Golgin subfamily A member 5 FapA PF03961.13 KIY68612.1 - 7.7 5.0 14.8 2.7 6.5 1.3 2.2 2 0 0 2 2 2 0 Flagellar Assembly Protein A V-SNARE PF05008.15 KIY68612.1 - 8.8 6.8 18.5 0.37 11.2 0.3 4.2 3 1 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus NAC PF01849.18 KIY68613.1 - 4.8e-20 71.3 0.0 8.7e-20 70.5 0.0 1.4 1 0 0 1 1 1 1 NAC domain UBA_4 PF14555.6 KIY68613.1 - 0.027 14.3 0.0 0.054 13.3 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain Methyltransf_11 PF08241.12 KIY68614.1 - 0.00018 22.1 0.0 0.00035 21.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIY68614.1 - 0.005 17.5 0.0 0.009 16.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIY68614.1 - 0.069 13.0 0.0 0.078 12.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 KIY68614.1 - 0.16 11.8 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain AAA PF00004.29 KIY68615.1 - 1.6e-44 151.6 0.1 4.7e-44 150.0 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KIY68615.1 - 1.6e-09 37.6 0.1 6.5e-09 35.6 0.0 2.1 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 KIY68615.1 - 4.9e-09 36.3 0.1 1.3e-08 34.9 0.1 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KIY68615.1 - 1.1e-07 32.4 0.1 3.6e-05 24.2 0.0 2.9 2 1 0 3 3 3 1 AAA ATPase domain AAA_2 PF07724.14 KIY68615.1 - 1.7e-06 28.3 0.0 4.2e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 KIY68615.1 - 6.2e-06 25.6 0.0 1.3e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 KIY68615.1 - 0.00023 21.2 0.0 0.0014 18.7 0.0 2.2 3 0 0 3 3 2 1 AAA domain RuvB_N PF05496.12 KIY68615.1 - 0.00035 20.4 0.0 0.0011 18.7 0.0 1.8 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 KIY68615.1 - 0.00042 20.6 0.0 0.0012 19.1 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_18 PF13238.6 KIY68615.1 - 0.00044 20.8 0.0 0.0057 17.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_lid_3 PF17862.1 KIY68615.1 - 0.0011 18.8 0.0 0.0025 17.6 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain RNA_helicase PF00910.22 KIY68615.1 - 0.0013 19.1 0.0 0.003 17.9 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_22 PF13401.6 KIY68615.1 - 0.0015 18.9 4.0 0.012 15.9 0.1 2.9 2 1 1 3 3 2 1 AAA domain TsaE PF02367.17 KIY68615.1 - 0.0016 18.5 0.0 0.005 16.8 0.0 1.9 2 0 0 2 2 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE NTPase_1 PF03266.15 KIY68615.1 - 0.0022 17.9 0.0 0.012 15.5 0.0 2.2 2 0 0 2 2 2 1 NTPase AAA_30 PF13604.6 KIY68615.1 - 0.0028 17.4 0.2 0.0074 16.0 0.2 1.8 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KIY68615.1 - 0.0036 16.8 0.1 0.023 14.2 0.1 2.1 1 1 0 1 1 1 1 P-loop containing dynein motor region CENP-F_leu_zip PF10473.9 KIY68615.1 - 0.0056 16.7 1.3 0.012 15.6 1.3 1.5 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IstB_IS21 PF01695.17 KIY68615.1 - 0.0062 16.3 0.1 0.021 14.6 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_33 PF13671.6 KIY68615.1 - 0.0068 16.6 0.0 0.017 15.3 0.0 1.8 2 0 0 2 2 1 1 AAA domain TniB PF05621.11 KIY68615.1 - 0.0082 15.6 0.0 0.53 9.7 0.0 2.3 2 0 0 2 2 2 1 Bacterial TniB protein Mg_chelatase PF01078.21 KIY68615.1 - 0.0083 15.5 0.1 0.019 14.3 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 KIY68615.1 - 0.0097 15.1 0.0 0.019 14.2 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_3 PF07726.11 KIY68615.1 - 0.011 15.6 0.0 0.026 14.4 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 KIY68615.1 - 0.013 15.0 0.3 0.052 13.1 0.1 1.9 1 1 1 2 2 2 0 AAA domain NACHT PF05729.12 KIY68615.1 - 0.018 14.9 0.1 0.078 12.9 0.0 2.0 2 0 0 2 2 2 0 NACHT domain AAA_24 PF13479.6 KIY68615.1 - 0.019 14.7 0.1 0.043 13.5 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KIY68615.1 - 0.028 14.2 0.3 0.069 12.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KIY68615.1 - 0.045 14.1 0.1 0.13 12.6 0.1 1.7 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KIY68615.1 - 0.048 13.4 0.1 1.1 9.0 0.0 2.6 3 0 0 3 3 2 0 Sigma-54 interaction domain AFG1_ATPase PF03969.16 KIY68615.1 - 0.055 12.3 0.4 0.13 11.2 0.0 1.7 2 0 0 2 2 2 0 AFG1-like ATPase ATPase_2 PF01637.18 KIY68615.1 - 0.082 12.8 0.5 0.6 10.0 0.0 2.5 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea ABC_tran PF00005.27 KIY68615.1 - 0.082 13.4 0.4 0.54 10.8 0.1 2.7 2 2 0 2 2 2 0 ABC transporter Bac_DnaA PF00308.18 KIY68615.1 - 0.092 12.6 0.0 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 Bacterial dnaA protein Parvo_NS1 PF01057.17 KIY68615.1 - 0.15 11.2 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 cobW PF02492.19 KIY68615.1 - 0.17 11.4 0.0 0.31 10.6 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 KIY68615.1 - 2.3 8.7 6.2 3.2 8.2 0.0 2.3 2 0 0 2 2 1 0 AAA domain P5CR_dimer PF14748.6 KIY68616.1 - 9.2e-39 131.9 2.6 1.5e-38 131.2 1.6 1.8 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 KIY68616.1 - 6.5e-10 39.5 0.0 1.8e-07 31.7 0.0 2.6 2 0 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent Glyco_tran_28_C PF04101.16 KIY68617.1 - 2.4e-26 92.7 0.0 2.7e-26 92.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Calcipressin PF04847.12 KIY68617.1 - 0.14 11.9 0.0 11 5.7 0.0 2.1 2 0 0 2 2 2 0 Calcipressin Thiolase_N PF00108.23 KIY68618.1 - 1.5e-85 286.7 0.6 1.5e-85 286.7 0.6 1.4 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KIY68618.1 - 2e-40 137.3 0.6 2e-40 137.3 0.6 1.9 2 0 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III_C PF08541.10 KIY68618.1 - 0.1 12.8 0.0 0.3 11.3 0.0 1.8 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Kdo PF06293.14 KIY68619.1 - 0.063 12.6 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kdo PF06293.14 KIY68620.1 - 0.018 14.4 0.0 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Flavin_Reduct PF01613.18 KIY68621.1 - 0.03 14.4 0.0 0.061 13.4 0.0 1.5 1 0 0 1 1 1 0 Flavin reductase like domain ATP-synt_DE PF00401.20 KIY68621.1 - 0.19 12.0 9.6 0.37 11.1 9.6 1.4 1 0 0 1 1 1 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain NYD-SP28_assoc PF14775.6 KIY68621.1 - 0.48 10.6 3.6 2.7 8.2 1.1 2.4 2 0 0 2 2 2 0 Sperm tail C-terminal domain Pkinase PF00069.25 KIY68622.1 - 1.7e-62 211.2 0.0 5.6e-62 209.5 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY68622.1 - 3.9e-33 114.8 0.0 2.3e-32 112.3 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 KIY68622.1 - 4.6e-16 58.4 0.0 7.8e-16 57.6 0.0 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.14 KIY68622.1 - 5.1e-06 26.0 0.2 8.8e-06 25.2 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KIY68622.1 - 9.1e-05 21.9 0.0 0.00016 21.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KIY68622.1 - 0.00045 19.3 0.2 0.00081 18.4 0.2 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KIY68622.1 - 0.0012 18.8 0.1 0.0046 16.9 0.1 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family PPP4R2 PF09184.11 KIY68623.1 - 1.3e-19 71.0 0.0 2.2e-19 70.2 0.0 1.3 1 0 0 1 1 1 1 PPP4R2 rRNA_processing PF08524.11 KIY68624.1 - 7.4e-06 26.1 12.4 6.6e-05 23.0 12.4 2.0 1 1 0 1 1 1 1 rRNA processing SUI1 PF01253.22 KIY68625.1 - 5.7e-27 94.1 0.4 7.3e-27 93.7 0.4 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 SNRNP27 PF08648.12 KIY68626.1 - 3.7e-29 100.6 0.7 6.5e-29 99.8 0.7 1.4 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins F-box-like PF12937.7 KIY68628.1 - 0.01 15.7 0.9 0.052 13.4 0.1 2.4 2 0 0 2 2 2 0 F-box-like RRM_1 PF00076.22 KIY68629.1 - 6.1e-11 42.0 0.0 1.7e-10 40.6 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NYN PF01936.18 KIY68630.1 - 4.3e-25 88.9 0.0 6.8e-25 88.3 0.0 1.2 1 0 0 1 1 1 1 NYN domain GBP_C PF02841.14 KIY68631.1 - 0.017 14.5 10.9 0.025 14.0 10.9 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Flavin_Reduct PF01613.18 KIY68631.1 - 0.039 14.0 0.0 0.075 13.1 0.0 1.4 1 0 0 1 1 1 0 Flavin reductase like domain PAP2 PF01569.21 KIY68632.1 - 2.8e-31 108.1 1.3 5.6e-31 107.1 1.3 1.5 1 0 0 1 1 1 1 PAP2 superfamily DUF5510 PF17629.2 KIY68632.1 - 0.19 11.7 0.3 0.64 10.0 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5510) DNA_pol_phi PF04931.13 KIY68633.1 - 7.7e-225 748.5 12.0 7.7e-225 748.5 12.0 1.9 3 0 0 3 3 3 1 DNA polymerase phi Pol_alpha_B_N PF08418.10 KIY68635.1 - 0.063 13.2 2.1 0.086 12.8 2.1 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal RCC1 PF00415.18 KIY68636.1 - 8.7e-21 74.3 15.0 3.9e-09 37.0 0.1 8.0 7 1 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KIY68636.1 - 9.3e-11 41.2 20.9 4e-06 26.5 0.4 6.8 7 0 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat SIS_2 PF13580.6 KIY68636.1 - 0.091 12.8 0.1 0.4 10.7 0.0 2.1 3 0 0 3 3 3 0 SIS domain NIF PF03031.18 KIY68637.1 - 6.2e-19 68.3 0.1 8.8e-19 67.8 0.1 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DPBB_1 PF03330.18 KIY68638.1 - 4.3e-06 26.9 0.1 3.7e-05 23.9 0.0 2.1 2 0 0 2 2 2 1 Lytic transglycolase Barwin PF00967.17 KIY68638.1 - 0.0035 17.2 0.0 0.0076 16.1 0.0 1.6 1 0 0 1 1 1 1 Barwin family SOG2 PF10428.9 KIY68638.1 - 4.8 6.3 17.0 6.4 5.8 17.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein BRF1 PF07741.13 KIY68639.1 - 6.7e-07 29.6 2.3 4e-06 27.1 0.7 2.5 2 1 0 2 2 2 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.12 KIY68639.1 - 0.0059 16.1 1.3 0.012 15.2 1.3 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding TFIIB PF00382.19 KIY68639.1 - 0.0073 16.3 0.8 0.019 15.0 0.1 2.1 2 0 0 2 2 2 1 Transcription factor TFIIB repeat Adeno_terminal PF02459.15 KIY68639.1 - 0.41 9.0 2.8 0.63 8.4 2.8 1.2 1 0 0 1 1 1 0 Adenoviral DNA terminal protein Glycos_transf_1 PF00534.20 KIY68640.1 - 9.9e-19 67.5 0.0 2.1e-18 66.5 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KIY68640.1 - 4.7e-12 46.5 0.0 1.1e-11 45.3 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KIY68640.1 - 0.00051 20.4 0.0 0.0013 19.1 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Gluconate_2-dh3 PF13618.6 KIY68640.1 - 0.2 11.9 0.0 0.56 10.4 0.0 1.8 2 0 0 2 2 2 0 Gluconate 2-dehydrogenase subunit 3 APH PF01636.23 KIY68641.1 - 1.2e-07 31.9 5.1 1.4e-05 25.1 0.6 3.0 2 2 1 3 3 3 2 Phosphotransferase enzyme family RIO1 PF01163.22 KIY68641.1 - 0.00088 18.9 0.0 0.0017 18.0 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KIY68641.1 - 0.051 12.9 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KIY68641.1 - 0.2 11.0 0.0 0.35 10.2 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain Plavaka PF18759.1 KIY68642.1 - 1.9e-13 50.4 1.2 2.9e-13 49.7 1.2 1.3 1 0 0 1 1 1 1 Plavaka transposase p450 PF00067.22 KIY68643.1 - 1.4e-53 182.4 0.1 4.2e-53 180.7 0.1 1.7 1 1 0 1 1 1 1 Cytochrome P450 DUF3829 PF12889.7 KIY68643.1 - 0.12 11.9 0.2 0.2 11.1 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3829) CagE_TrbE_VirB PF03135.14 KIY68643.1 - 0.23 11.6 0.5 0.95 9.5 0.6 1.8 1 1 1 2 2 2 0 CagE, TrbE, VirB family, component of type IV transporter system RRM_1 PF00076.22 KIY68644.1 - 7.5e-48 160.2 0.0 1.6e-16 59.9 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 KIY68644.1 - 0.005 16.9 0.0 1.1 9.3 0.0 3.3 3 1 0 3 3 3 1 Limkain b1 RRM_5 PF13893.6 KIY68644.1 - 0.0062 16.1 0.0 12 5.5 0.0 3.1 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KIY68644.1 - 0.0097 15.9 0.0 5 7.2 0.0 3.1 3 0 0 3 3 3 1 RNA binding motif DUF3343 PF11823.8 KIY68644.1 - 0.02 14.3 0.0 0.06 12.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3343) Presenilin PF01080.17 KIY68644.1 - 3.4 6.3 3.7 4.4 6.0 3.7 1.1 1 0 0 1 1 1 0 Presenilin Apt1 PF10351.9 KIY68644.1 - 7.8 5.2 13.8 9.9 4.9 13.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain F-box-like PF12937.7 KIY68646.1 - 6.1e-07 29.2 3.8 6e-06 26.1 0.8 3.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIY68646.1 - 0.56 10.1 0.1 0.56 10.1 0.1 3.2 3 0 0 3 3 3 0 F-box domain F-box-like PF12937.7 KIY68647.1 - 7.2e-08 32.2 1.2 1.9e-07 30.8 0.2 2.3 2 1 0 2 2 2 1 F-box-like Abhydrolase_1 PF00561.20 KIY68650.1 - 2.7e-24 86.2 0.4 3.5e-24 85.9 0.4 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIY68650.1 - 7.9e-14 52.8 0.8 1e-13 52.4 0.8 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIY68650.1 - 0.03 13.6 0.0 0.66 9.2 0.0 2.4 2 1 0 2 2 2 0 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 KIY68650.1 - 0.11 11.4 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Peripla_BP_3 PF13377.6 KIY68650.1 - 0.12 12.7 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 Periplasmic binding protein-like domain Glyco_transf_20 PF00982.21 KIY68652.1 - 1.2e-149 499.0 0.0 1.7e-149 498.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 KIY68652.1 - 2.3e-66 223.3 0.0 6.5e-66 221.8 0.0 1.7 2 0 0 2 2 2 1 Trehalose-phosphatase RNase_II_C_S1 PF18614.1 KIY68652.1 - 0.11 12.5 0.3 0.47 10.4 0.2 2.1 2 0 0 2 2 2 0 RNase II-type exonuclease C-terminal S1 domain Aldedh PF00171.22 KIY68653.1 - 3.3e-90 302.8 0.0 4e-90 302.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Peptidase_S41 PF03572.18 KIY68655.1 - 1.5e-05 24.6 0.0 3.5e-05 23.5 0.0 1.5 1 1 0 1 1 1 1 Peptidase family S41 Abhydrolase_1 PF00561.20 KIY68656.1 - 3.7e-23 82.5 0.7 4.8e-23 82.1 0.7 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIY68656.1 - 6.5e-14 53.1 1.5 8e-14 52.8 1.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIY68656.1 - 0.05 12.9 0.0 0.24 10.7 0.0 2.2 1 1 0 1 1 1 0 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 KIY68656.1 - 0.16 10.9 0.0 0.24 10.3 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme DUF5133 PF17196.4 KIY68658.1 - 0.16 12.2 0.9 0.5 10.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF5133) Fungus-induced PF10917.8 KIY68660.1 - 0.1 12.9 0.1 0.1 12.9 0.1 1.9 2 0 0 2 2 2 0 Fungus-induced protein MULE PF10551.9 KIY68663.1 - 5.8e-06 26.6 0.0 1.1e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 MULE transposase domain SWIM PF04434.17 KIY68663.1 - 0.029 14.0 0.0 0.068 12.8 0.0 1.7 1 0 0 1 1 1 0 SWIM zinc finger MULE PF10551.9 KIY68664.1 - 4.6e-12 46.2 0.0 1e-11 45.0 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain ADH_zinc_N PF00107.26 KIY68665.1 - 1.2e-20 73.8 0.3 1.6e-19 70.2 0.2 2.5 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KIY68665.1 - 8.8e-17 62.4 0.3 1.5e-14 55.2 0.1 2.9 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIY68665.1 - 0.028 14.3 0.0 0.06 13.2 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain CsbD PF05532.12 KIY68666.1 - 5.5e-14 51.8 14.5 1.4e-07 31.3 1.9 2.1 1 1 1 2 2 2 2 CsbD-like HSP9_HSP12 PF04119.12 KIY68666.1 - 0.094 13.1 1.9 0.17 12.3 0.3 2.2 2 1 0 2 2 2 0 Heat shock protein 9/12 Peptidase_M35 PF02102.15 KIY68667.1 - 2.7e-35 121.9 16.5 3.3e-35 121.6 16.5 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 KIY68667.1 - 2.5e-22 80.0 4.1 3.9e-22 79.4 4.1 1.3 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase HRXXH PF13933.6 KIY68667.1 - 4.5e-07 29.7 4.5 8.1e-07 28.9 4.5 1.4 1 1 0 1 1 1 1 Putative peptidase family TPP_enzyme_N PF02776.18 KIY68669.1 - 8e-34 116.7 0.0 1.4e-33 115.9 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KIY68669.1 - 8.7e-15 54.8 0.0 2.2e-14 53.5 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KIY68669.1 - 9.4e-14 51.3 0.0 2.1e-13 50.2 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain EMP24_GP25L PF01105.24 KIY68670.1 - 2e-35 122.4 0.0 2.6e-35 122.0 0.0 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Cyclin_N PF00134.23 KIY68671.1 - 4.4e-15 55.5 0.2 7.8e-15 54.7 0.2 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 KIY68671.1 - 3.1e-12 47.2 0.1 3.1e-12 47.2 0.1 2.3 2 1 0 2 2 2 1 Cyclin Serglycin PF04360.12 KIY68671.1 - 0.021 14.8 1.2 0.035 14.1 1.2 1.3 1 0 0 1 1 1 0 Serglycin TEBP_beta PF07404.11 KIY68671.1 - 0.15 11.4 3.1 0.25 10.6 3.1 1.3 1 0 0 1 1 1 0 Telomere-binding protein beta subunit (TEBP beta) DJ-1_PfpI PF01965.24 KIY68672.1 - 1.1e-15 57.8 0.0 2.4e-10 40.5 0.0 2.1 1 1 1 2 2 2 2 DJ-1/PfpI family ThiJ_like PF17124.5 KIY68672.1 - 0.0033 17.2 0.0 0.029 14.1 0.0 2.0 1 1 1 2 2 2 1 ThiJ/PfpI family-like AIM24 PF01987.17 KIY68673.1 - 7.9e-51 172.7 0.2 9.2e-51 172.5 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 CTP_transf_like PF01467.26 KIY68674.1 - 4.7e-05 23.6 0.0 0.00022 21.4 0.0 2.0 1 1 0 1 1 1 1 Cytidylyltransferase-like LexA_DNA_bind PF01726.16 KIY68674.1 - 0.085 12.6 0.6 0.63 9.9 0.0 2.5 3 0 0 3 3 3 0 LexA DNA binding domain Kin17_mid PF10357.9 KIY68675.1 - 1.8e-50 170.1 1.0 3.3e-50 169.2 1.0 1.4 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein zf-met PF12874.7 KIY68675.1 - 0.0018 18.6 5.3 0.0043 17.4 5.3 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KIY68675.1 - 0.12 12.6 4.4 0.36 11.2 4.4 1.9 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KIY68675.1 - 0.21 12.0 4.5 0.15 12.4 1.5 2.0 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) ABC_tran PF00005.27 KIY68677.1 - 1.2e-19 71.2 0.0 1.9e-19 70.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KIY68677.1 - 2.4e-07 30.4 0.1 0.017 14.6 0.8 2.1 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KIY68677.1 - 1.9e-06 27.9 0.1 0.0035 17.2 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KIY68677.1 - 4.6e-05 23.3 0.0 0.00019 21.3 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 KIY68677.1 - 0.0016 19.0 0.0 0.0032 18.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KIY68677.1 - 0.005 16.5 0.1 0.009 15.7 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 KIY68677.1 - 0.0051 17.2 0.2 0.0098 16.3 0.2 1.7 1 1 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.13 KIY68677.1 - 0.011 14.9 0.0 0.021 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_30 PF13604.6 KIY68677.1 - 0.016 14.9 0.0 0.17 11.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KIY68677.1 - 0.017 15.6 0.1 0.23 12.0 0.0 2.6 3 0 0 3 3 3 0 AAA domain RsgA_GTPase PF03193.16 KIY68677.1 - 0.023 14.6 0.0 0.041 13.8 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_22 PF13401.6 KIY68677.1 - 0.042 14.1 0.0 0.47 10.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 KIY68677.1 - 0.1 11.8 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit AAA_27 PF13514.6 KIY68677.1 - 0.11 12.1 0.0 0.27 10.8 0.0 1.6 2 0 0 2 2 2 0 AAA domain MTS_N PF08468.11 KIY68677.1 - 0.13 12.3 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain N-terminal DUF87 PF01935.17 KIY68677.1 - 0.16 12.0 0.2 0.4 10.7 0.2 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain Peptidase_C54 PF03416.19 KIY68678.1 - 2.4e-99 332.2 0.0 2.9e-99 332.0 0.0 1.0 1 0 0 1 1 1 1 Peptidase family C54 TerY_C PF15616.6 KIY68681.1 - 0.011 15.8 0.5 0.011 15.8 0.5 2.2 2 0 0 2 2 2 0 TerY-C metal binding domain DUF1658 PF07871.11 KIY68682.1 - 0.071 13.1 1.7 0.074 13.0 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1658) Ndufs5 PF10200.9 KIY68688.1 - 0.00039 20.6 0.3 0.00048 20.3 0.3 1.2 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF3128 PF11326.8 KIY68688.1 - 0.84 10.1 5.3 3.2 8.2 5.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) PAS_10 PF13596.6 KIY68689.1 - 0.12 13.0 0.0 0.16 12.6 0.0 1.2 1 0 0 1 1 1 0 PAS domain Cation_ATPase_C PF00689.21 KIY68691.1 - 4.6e-51 173.1 4.1 4.6e-51 173.1 4.1 2.8 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KIY68691.1 - 8.5e-41 139.5 0.5 8.5e-41 139.5 0.5 2.5 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 KIY68691.1 - 2.6e-21 75.5 0.0 7e-21 74.1 0.0 1.8 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KIY68691.1 - 1.3e-18 68.1 3.4 2.4e-16 60.6 3.4 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KIY68691.1 - 5.7e-09 35.5 0.6 3e-08 33.2 0.0 2.5 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KIY68691.1 - 0.00011 22.0 0.3 0.011 15.5 0.3 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase DUF3533 PF12051.8 KIY68692.1 - 3.8e-88 296.0 14.6 4.9e-88 295.6 14.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) PMP1_2 PF08114.11 KIY68692.1 - 0.031 14.0 1.0 0.14 11.9 1.0 2.2 1 0 0 1 1 1 0 ATPase proteolipid family TMEM40 PF15817.5 KIY68692.1 - 0.19 11.5 5.9 0.045 13.5 0.9 2.5 1 1 0 2 2 2 0 Transmembrane protein 40 family Phage_holin_3_6 PF07332.11 KIY68694.1 - 0.13 12.3 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III LapA_dom PF06305.11 KIY68694.1 - 0.33 10.8 1.0 0.55 10.1 1.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain ADH_N PF08240.12 KIY68695.1 - 1.7e-28 98.7 6.4 5.2e-28 97.1 1.7 2.4 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KIY68695.1 - 2.2e-21 76.2 0.2 3.9e-21 75.4 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KIY68695.1 - 4.3e-10 39.4 0.2 2.6e-09 36.9 0.2 2.1 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KIY68695.1 - 0.00011 23.3 0.0 0.00023 22.2 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KIY68695.1 - 0.0023 17.2 0.5 0.0023 17.2 0.5 2.1 2 1 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 KIY68695.1 - 0.011 15.3 0.1 0.026 14.1 0.1 1.7 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.18 KIY68695.1 - 0.044 14.0 0.1 0.083 13.2 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain Chlam_OMP6 PF03504.13 KIY68695.1 - 0.062 13.6 0.0 0.31 11.4 0.0 2.2 3 0 0 3 3 3 0 Chlamydia cysteine-rich outer membrane protein 6 YdfZ PF14001.6 KIY68695.1 - 0.074 13.5 0.3 0.46 10.9 0.0 2.4 2 0 0 2 2 2 0 YdfZ protein Gpr1_Fun34_YaaH PF01184.19 KIY68699.1 - 2.1e-42 145.1 13.0 2.6e-42 144.8 13.0 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family GLTP PF08718.11 KIY68700.1 - 1.2e-34 119.8 0.2 1.6e-33 116.1 0.2 2.0 1 1 0 1 1 1 1 Glycolipid transfer protein (GLTP) Abhydrolase_6 PF12697.7 KIY68701.1 - 1.6e-10 42.0 0.2 1.6e-10 42.0 0.2 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KIY68701.1 - 0.0082 15.6 0.0 0.028 13.9 0.0 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KIY68701.1 - 0.012 14.9 0.0 0.021 14.1 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KIY68701.1 - 0.013 15.1 0.0 0.027 14.1 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.20 KIY68701.1 - 0.066 12.8 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Putative esterase SPT2 PF08243.11 KIY68702.1 - 1e-15 58.2 9.2 1e-15 58.2 9.2 3.3 2 1 1 3 3 3 1 SPT2 chromatin protein SPA PF08616.10 KIY68703.1 - 5.7e-08 32.7 0.0 9.5e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis CysG_dimeriser PF10414.9 KIY68703.1 - 0.14 11.9 0.0 0.33 10.7 0.0 1.7 1 0 0 1 1 1 0 Sirohaem synthase dimerisation region WD40 PF00400.32 KIY68704.1 - 7e-46 153.3 19.7 1.9e-10 41.1 0.6 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY68704.1 - 4.5e-18 65.3 1.2 0.00031 21.0 0.1 5.4 3 3 4 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIY68704.1 - 8.7e-09 34.8 0.0 0.18 10.7 0.0 4.6 2 1 3 5 5 5 4 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KIY68704.1 - 3.6e-06 27.0 0.0 0.009 15.9 0.1 2.6 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 KIY68704.1 - 0.0068 14.5 1.2 1.7 6.5 0.2 2.5 2 1 0 2 2 2 2 IKI3 family Lactonase PF10282.9 KIY68704.1 - 0.018 14.3 0.0 4.2 6.5 0.0 2.8 1 1 1 3 3 3 0 Lactonase, 7-bladed beta-propeller PD40 PF07676.12 KIY68704.1 - 0.06 13.3 1.8 2.2 8.3 0.2 3.2 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat SnoaL_2 PF12680.7 KIY68706.1 - 1.1e-06 29.2 0.0 1.9e-06 28.5 0.0 1.4 1 1 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 KIY68706.1 - 3.7e-05 23.5 0.1 4.8e-05 23.1 0.1 1.2 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase cobW PF02492.19 KIY68707.1 - 5.1e-33 114.1 0.0 6.1e-33 113.9 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 KIY68707.1 - 0.00091 18.3 0.0 0.056 12.4 0.0 2.1 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 KIY68707.1 - 0.007 16.4 0.0 0.015 15.4 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 KIY68707.1 - 0.054 14.0 0.0 0.086 13.4 0.0 1.3 1 0 0 1 1 1 0 ABC transporter TIP49 PF06068.13 KIY68707.1 - 0.056 12.6 0.0 0.081 12.1 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_5 PF07728.14 KIY68707.1 - 0.077 13.0 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KIY68707.1 - 0.1 13.2 0.0 0.15 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KIY68707.1 - 0.11 12.3 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein TsaE PF02367.17 KIY68707.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE T2SSE PF00437.20 KIY68707.1 - 0.12 11.4 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Zeta_toxin PF06414.12 KIY68707.1 - 0.13 11.5 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin GTP_EFTU PF00009.27 KIY68707.1 - 0.17 11.4 0.1 1.7 8.2 0.1 2.4 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain DUF1996 PF09362.10 KIY68708.1 - 1.3e-78 264.2 0.3 1.9e-78 263.7 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) DUF515 PF04415.12 KIY68708.1 - 0.6 8.4 5.0 0.78 8.1 5.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Sporozoite_P67 PF05642.11 KIY68708.1 - 1.2 7.1 5.8 1.6 6.7 5.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RSRP PF17069.5 KIY68708.1 - 2.7 7.5 16.9 4.2 6.9 16.9 1.2 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 Mog1 PF04603.12 KIY68709.1 - 1.8e-40 138.5 0.1 2.1e-40 138.3 0.1 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein MFS_1 PF07690.16 KIY68710.1 - 1.1e-26 93.7 29.7 1.1e-26 93.7 29.7 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Zip PF02535.22 KIY68711.1 - 0.34 10.1 2.1 0.41 9.8 2.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4834 PF16118.5 KIY68711.1 - 8.3 7.4 8.4 2 9.4 3.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) NmrA PF05368.13 KIY68712.1 - 1.7e-40 139.0 0.0 2.1e-40 138.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KIY68712.1 - 7e-12 45.6 0.0 1e-11 45.1 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KIY68712.1 - 0.00025 20.6 0.1 0.00036 20.1 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KIY68712.1 - 0.0047 16.0 0.0 0.0064 15.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 KIY68712.1 - 0.0095 16.4 0.1 0.015 15.7 0.1 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Arch_fla_DE PF04659.13 KIY68713.1 - 0.049 13.5 0.1 0.11 12.4 0.1 1.6 1 0 0 1 1 1 0 Archaeal flagella protein Transketolase_N PF00456.21 KIY68716.1 - 5.1e-16 58.5 0.5 6.8e-15 54.9 0.5 2.1 1 1 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transketolase_C PF02780.20 KIY68716.1 - 1.8e-07 31.1 0.0 3.6e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain Transket_pyr PF02779.24 KIY68716.1 - 1.6e-05 24.6 0.6 5.3e-05 23.0 0.2 2.1 2 1 0 2 2 2 1 Transketolase, pyrimidine binding domain TPP_enzyme_C PF02775.21 KIY68716.1 - 0.00014 21.7 0.1 0.00069 19.4 0.1 2.0 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.20 KIY68716.1 - 0.0038 16.2 0.0 0.0071 15.3 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component Peptidase_M36 PF02128.15 KIY68719.1 - 1.2e-138 462.3 6.1 1.5e-138 462.0 6.1 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) Peptidase_M4_C PF02868.15 KIY68719.1 - 0.001 19.0 0.0 0.0026 17.6 0.0 1.6 1 0 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain Peptidase_M36 PF02128.15 KIY68720.1 - 2.8e-132 441.4 5.1 3.6e-132 441.0 5.1 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.13 KIY68720.1 - 0.00091 19.0 0.2 0.0022 17.8 0.2 1.7 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif F-box-like PF12937.7 KIY68722.1 - 0.0015 18.4 0.1 0.0039 17.1 0.1 1.8 1 0 0 1 1 1 1 F-box-like Homeodomain PF00046.29 KIY68723.1 - 5.3e-15 55.0 1.1 1.2e-14 53.9 1.1 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KIY68723.1 - 0.021 14.7 0.1 0.055 13.4 0.1 1.7 1 0 0 1 1 1 0 Homeobox KN domain Kinesin PF00225.23 KIY68725.1 - 1.1e-89 300.6 0.0 2e-89 299.8 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KIY68725.1 - 1.3e-23 83.6 0.0 3.6e-23 82.2 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding Pro_dh PF01619.18 KIY68725.1 - 0.012 15.2 1.4 0.02 14.4 1.4 1.3 1 0 0 1 1 1 0 Proline dehydrogenase PhoH PF02562.16 KIY68725.1 - 0.15 11.5 0.6 0.82 9.1 0.1 2.1 2 0 0 2 2 2 0 PhoH-like protein Peptidase_M20 PF01546.28 KIY68726.1 - 4.2e-33 114.8 0.0 5.2e-33 114.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KIY68726.1 - 3.7e-09 36.5 0.0 6.7e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KIY68726.1 - 0.0038 16.9 0.0 0.0072 16.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Vps39_1 PF10366.9 KIY68727.1 - 1.6e-26 92.7 0.2 8.1e-26 90.4 0.0 2.4 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.9 KIY68727.1 - 1.9e-21 76.5 0.1 5e-21 75.2 0.1 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.22 KIY68727.1 - 3.2e-15 56.5 0.0 5.9e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 CNH domain Clathrin PF00637.20 KIY68727.1 - 1.3e-10 41.4 2.6 9.4e-08 32.0 1.3 2.6 2 0 0 2 2 2 2 Region in Clathrin and VPS TPR_19 PF14559.6 KIY68727.1 - 0.00029 21.3 8.1 0.038 14.5 0.1 3.9 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 KIY68727.1 - 0.13 13.1 5.1 9.9 7.3 0.1 4.3 3 1 1 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KIY68727.1 - 1.6 9.0 5.5 1.2 9.4 0.1 3.2 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 KIY68727.1 - 2.5 8.1 13.5 7.2 6.6 0.1 4.4 4 1 1 5 5 5 0 Tetratricopeptide repeat Ank_2 PF12796.7 KIY68729.1 - 7.4e-23 80.9 0.0 1.1e-06 29.2 0.0 4.8 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KIY68729.1 - 1.8e-20 73.0 2.5 0.0025 18.3 0.0 6.2 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 KIY68729.1 - 6.8e-19 67.7 4.6 0.00026 21.2 0.0 5.6 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 KIY68729.1 - 3.6e-15 55.6 0.1 0.025 15.0 0.0 7.4 7 0 0 7 7 7 4 Ankyrin repeat Ank_3 PF13606.6 KIY68729.1 - 1.3e-14 52.8 1.4 0.005 17.2 0.0 7.5 7 1 0 7 7 7 3 Ankyrin repeat TAP_C PF03943.13 KIY68730.1 - 0.0022 17.6 0.0 0.0054 16.3 0.0 1.7 1 0 0 1 1 1 1 TAP C-terminal domain UBA_4 PF14555.6 KIY68730.1 - 0.0046 16.8 0.0 0.01 15.6 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain LRR_9 PF14580.6 KIY68730.1 - 0.01 15.3 0.2 0.019 14.5 0.2 1.3 1 0 0 1 1 1 0 Leucine-rich repeat NTF2 PF02136.20 KIY68730.1 - 0.085 13.4 0.0 5.2 7.7 0.0 3.1 3 0 0 3 3 3 0 Nuclear transport factor 2 (NTF2) domain LRR_8 PF13855.6 KIY68730.1 - 2.3 8.1 7.9 11 5.9 4.5 2.6 1 1 0 2 2 2 0 Leucine rich repeat LRR_1 PF00560.33 KIY68730.1 - 3.6 8.5 4.5 1.5e+02 3.6 0.0 3.4 2 1 0 2 2 2 0 Leucine Rich Repeat HAD_2 PF13419.6 KIY68731.1 - 1.3e-22 80.8 0.0 1.9e-22 80.2 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KIY68731.1 - 3.7e-10 40.4 0.0 1.9e-09 38.1 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KIY68731.1 - 1.2e-05 25.2 0.0 2.1e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 KIY68731.1 - 0.0012 19.3 0.0 0.0016 18.9 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Phasin PF05597.11 KIY68732.1 - 0.14 12.2 0.1 0.14 12.2 0.1 2.6 3 0 0 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Snapin_Pallidin PF14712.6 KIY68732.1 - 9 6.8 7.6 9.1 6.8 1.0 2.9 3 0 0 3 3 3 0 Snapin/Pallidin FMN_dh PF01070.18 KIY68734.1 - 1.3e-79 267.8 0.0 4.5e-50 170.6 0.0 2.0 1 1 1 2 2 2 2 FMN-dependent dehydrogenase DHO_dh PF01180.21 KIY68734.1 - 0.0099 15.1 0.1 0.024 13.8 0.0 1.7 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase ThiG PF05690.14 KIY68734.1 - 0.028 13.7 0.0 2.8 7.2 0.0 2.5 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG IMPDH PF00478.25 KIY68734.1 - 0.048 12.7 0.0 0.088 11.8 0.0 1.5 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain HMD PF03201.16 KIY68734.1 - 0.22 11.8 0.5 2.9 8.2 0.1 2.4 2 0 0 2 2 2 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase FabA PF07977.13 KIY68736.1 - 0.23 11.1 0.2 0.35 10.5 0.2 1.2 1 0 0 1 1 1 0 FabA-like domain SlyX PF04102.12 KIY68737.1 - 0.032 14.9 0.9 0.032 14.9 0.9 2.0 2 0 0 2 2 2 0 SlyX DUF3918 PF13056.6 KIY68737.1 - 0.13 11.9 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3918) ERAP1_C PF11838.8 KIY68739.1 - 3.2e-68 230.6 0.9 7.4e-68 229.4 0.2 1.8 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 KIY68739.1 - 1.3e-64 217.7 0.0 2.3e-64 216.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 KIY68739.1 - 8.8e-43 146.7 0.2 1.6e-41 142.5 0.2 2.3 1 1 0 1 1 1 1 Peptidase M1 N-terminal domain FAD_binding_3 PF01494.19 KIY68740.1 - 6.2e-20 71.7 0.8 2.2e-10 40.3 0.1 2.4 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KIY68740.1 - 0.00037 20.6 0.1 0.0015 18.8 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KIY68740.1 - 0.00093 18.9 0.2 0.0018 17.9 0.2 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KIY68740.1 - 0.0046 17.0 0.1 0.018 15.0 0.1 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KIY68740.1 - 0.0049 16.1 0.3 0.05 12.8 0.3 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KIY68740.1 - 0.023 13.5 0.2 0.28 10.0 0.1 2.0 1 1 1 2 2 2 0 Tryptophan halogenase RPN7 PF10602.9 KIY68741.1 - 1e-49 168.6 0.4 1.8e-49 167.8 0.1 1.6 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.27 KIY68741.1 - 7.1e-18 65.1 0.2 3e-17 63.1 0.0 2.1 2 1 0 2 2 2 1 PCI domain FeoB_Cyto PF17910.1 KIY68741.1 - 0.088 13.4 1.1 0.24 12.0 1.1 1.8 1 0 0 1 1 1 0 FeoB cytosolic helical domain TPX2 PF06886.11 KIY68741.1 - 9.9 6.5 10.1 0.15 12.3 0.7 2.3 1 1 1 2 2 2 0 Targeting protein for Xklp2 (TPX2) CK_II_beta PF01214.18 KIY68742.1 - 0.023 14.5 0.0 0.038 13.8 0.0 1.3 1 0 0 1 1 1 0 Casein kinase II regulatory subunit Complex1_51K PF01512.17 KIY68743.1 - 7e-48 162.4 0.0 1.1e-47 161.7 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 KIY68743.1 - 7.3e-32 109.3 0.2 1.4e-31 108.4 0.2 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 KIY68743.1 - 9.2e-09 35.0 0.0 2.2e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 SLBB domain ABC2_membrane PF01061.24 KIY68744.1 - 1.5e-69 233.6 59.6 1.1e-39 136.1 23.5 2.9 4 0 0 4 4 3 2 ABC-2 type transporter ABC_tran PF00005.27 KIY68744.1 - 1.8e-40 138.6 0.0 3.6e-19 69.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KIY68744.1 - 5.8e-33 112.7 3.7 3.2e-28 97.5 0.1 3.1 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.6 KIY68744.1 - 4.2e-12 46.5 1.3 7e-11 42.6 0.1 3.0 3 0 0 3 3 2 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 KIY68744.1 - 5e-10 39.0 42.9 2.1e-05 23.8 20.1 2.9 2 1 0 2 2 2 2 ABC-2 family transporter protein RsgA_GTPase PF03193.16 KIY68744.1 - 9.7e-09 35.3 0.6 9.3e-07 28.9 0.2 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KIY68744.1 - 2.6e-07 31.2 0.2 0.0027 18.1 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KIY68744.1 - 2.2e-06 28.0 0.4 0.027 14.8 0.3 3.1 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KIY68744.1 - 6.5e-05 22.6 0.2 0.097 12.4 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_33 PF13671.6 KIY68744.1 - 0.00018 21.7 0.2 0.89 9.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 KIY68744.1 - 0.0012 18.5 0.7 0.12 12.0 0.1 3.1 3 0 0 3 3 3 1 AAA domain cobW PF02492.19 KIY68744.1 - 0.0015 18.2 0.7 0.23 11.0 0.1 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 KIY68744.1 - 0.0017 18.4 0.4 1 9.5 0.2 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_18 PF13238.6 KIY68744.1 - 0.0024 18.4 0.0 0.59 10.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KIY68744.1 - 0.0028 17.6 1.8 0.12 12.3 0.2 2.5 2 0 0 2 2 2 1 NACHT domain AAA_17 PF13207.6 KIY68744.1 - 0.0046 17.4 0.1 2.7 8.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain dNK PF01712.19 KIY68744.1 - 0.0053 16.6 0.0 0.19 11.6 0.0 2.3 2 0 0 2 2 2 1 Deoxynucleoside kinase AAA_28 PF13521.6 KIY68744.1 - 0.0055 17.0 1.0 0.67 10.2 0.4 2.7 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KIY68744.1 - 0.01 15.7 0.1 4.2 7.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Zeta_toxin PF06414.12 KIY68744.1 - 0.024 13.9 0.3 3 7.1 0.1 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_30 PF13604.6 KIY68744.1 - 0.033 13.9 1.1 0.69 9.6 0.2 2.8 3 0 0 3 3 3 0 AAA domain Ploopntkinase3 PF18751.1 KIY68744.1 - 0.071 13.0 0.4 1.5 8.7 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 Rad17 PF03215.15 KIY68744.1 - 0.11 12.4 0.0 8.9 6.2 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain AAA PF00004.29 KIY68744.1 - 0.12 12.8 0.2 2.6 8.5 0.2 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 KIY68744.1 - 0.13 12.2 1.1 0.29 11.2 0.1 2.0 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_13 PF13166.6 KIY68744.1 - 0.18 10.4 0.1 1.8 7.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 KIY68744.1 - 0.18 11.0 0.1 8.3 5.6 0.1 2.2 2 0 0 2 2 2 0 Septin AAA_23 PF13476.6 KIY68744.1 - 0.19 12.2 0.0 0.43 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KIY68744.1 - 0.26 11.2 1.5 2 8.3 0.2 2.7 3 0 0 3 3 3 0 NTPase PduV-EutP PF10662.9 KIY68744.1 - 0.84 9.4 2.3 4.7 6.9 0.1 2.7 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Ribosomal_L10 PF00466.20 KIY68746.1 - 3.3e-25 88.1 0.7 1.9e-24 85.7 0.1 2.1 2 0 0 2 2 2 1 Ribosomal protein L10 Ribosomal_60s PF00428.19 KIY68746.1 - 3.8e-22 78.7 13.3 4.8e-22 78.3 10.3 2.1 2 0 0 2 2 2 1 60s Acidic ribosomal protein RL10P_insert PF17777.1 KIY68746.1 - 6.7e-22 77.3 0.1 1.2e-21 76.5 0.1 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P CBM_21 PF03370.13 KIY68748.1 - 3.7e-25 88.3 0.0 6.1e-25 87.6 0.0 1.4 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 KIY68748.1 - 3.3e-08 34.0 0.0 9.4e-08 32.5 0.0 1.7 2 0 0 2 2 2 1 Starch/carbohydrate-binding module (family 53) Pkinase PF00069.25 KIY68749.1 - 1.2e-34 119.8 0.0 7.3e-34 117.3 0.0 2.1 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY68749.1 - 1.1e-21 77.4 0.0 2e-19 69.9 0.0 3.0 2 1 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 KIY68749.1 - 0.00024 20.5 0.0 0.00047 19.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KIY68749.1 - 0.082 12.2 0.0 5.8 6.1 0.0 2.1 2 0 0 2 2 2 0 Kinase-like DRAT PF07357.11 KIY68750.1 - 0.17 11.1 1.1 0.3 10.2 1.1 1.3 1 0 0 1 1 1 0 Dinitrogenase reductase ADP-ribosyltransferase (DRAT) V_ATPase_I PF01496.19 KIY68750.1 - 0.71 7.7 1.8 12 3.6 0.2 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF724 PF05266.14 KIY68750.1 - 0.81 9.5 6.6 1.3 8.8 0.4 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF724) Fungal_trans PF04082.18 KIY68751.1 - 1.6e-08 34.0 0.1 2.8e-08 33.1 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY68751.1 - 5.5e-07 29.6 13.3 9.4e-07 28.9 13.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dna2 PF08696.11 KIY68752.1 - 0.39 10.5 2.3 3 7.6 2.3 2.0 1 1 0 1 1 1 0 DNA replication factor Dna2 V_ATPase_I PF01496.19 KIY68753.1 - 0 1067.1 0.0 0 1066.9 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family SlyX PF04102.12 KIY68753.1 - 0.057 14.0 1.8 0.37 11.4 1.3 2.5 3 0 0 3 3 3 0 SlyX ABC_tran PF00005.27 KIY68755.1 - 2.8e-42 144.5 0.0 5e-20 72.4 0.0 3.8 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KIY68755.1 - 1.5e-17 64.4 2.7 5.3e-07 29.7 0.3 4.7 2 2 1 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KIY68755.1 - 1.6e-13 50.6 0.2 0.0016 17.9 0.0 4.3 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KIY68755.1 - 9.4e-08 31.7 0.1 0.015 15.0 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KIY68755.1 - 2.9e-06 27.9 6.9 0.0013 19.3 0.0 3.1 3 1 0 3 3 2 2 AAA domain DUF87 PF01935.17 KIY68755.1 - 3.2e-06 27.4 0.0 0.0019 18.4 0.0 3.0 3 0 0 3 3 2 1 Helicase HerA, central domain AAA_18 PF13238.6 KIY68755.1 - 4.6e-06 27.2 0.1 0.015 15.8 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.6 KIY68755.1 - 8.2e-06 26.1 0.0 0.18 12.1 0.0 3.6 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.23 KIY68755.1 - 4.5e-05 23.5 0.0 0.26 11.4 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIY68755.1 - 6.8e-05 22.8 0.0 0.22 11.4 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_15 PF13175.6 KIY68755.1 - 6.8e-05 22.7 0.0 0.29 10.8 0.0 3.0 3 0 0 3 3 2 2 AAA ATPase domain AAA_16 PF13191.6 KIY68755.1 - 7.1e-05 23.3 0.1 0.13 12.6 0.0 3.7 4 0 0 4 4 3 1 AAA ATPase domain RNA_helicase PF00910.22 KIY68755.1 - 0.0001 22.6 0.0 0.45 10.9 0.0 2.9 2 0 0 2 2 2 2 RNA helicase AAA PF00004.29 KIY68755.1 - 0.00013 22.4 0.0 2.8 8.4 0.0 4.2 4 1 1 5 5 5 2 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 KIY68755.1 - 0.00015 21.8 0.1 1.1 9.1 0.0 3.6 3 0 0 3 3 3 1 ATPase domain predominantly from Archaea NACHT PF05729.12 KIY68755.1 - 0.00039 20.4 0.1 0.74 9.7 0.0 2.7 2 0 0 2 2 2 2 NACHT domain AAA_28 PF13521.6 KIY68755.1 - 0.00075 19.8 0.0 1.3 9.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 KIY68755.1 - 0.00093 19.4 0.0 2.5 8.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain Chromo PF00385.24 KIY68755.1 - 0.0015 18.4 0.1 0.0034 17.3 0.1 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain MeaB PF03308.16 KIY68755.1 - 0.0016 17.5 0.5 0.24 10.3 0.1 2.7 3 0 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_7 PF12775.7 KIY68755.1 - 0.0026 17.3 0.1 2.8 7.4 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region HEAT_2 PF13646.6 KIY68755.1 - 0.0047 17.3 7.4 2.2 8.7 2.7 4.0 2 1 2 4 4 3 2 HEAT repeats SbcCD_C PF13558.6 KIY68755.1 - 0.012 15.9 0.1 1 9.7 0.0 3.4 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 KIY68755.1 - 0.012 15.4 1.3 4.9 6.8 0.2 3.4 4 0 0 4 4 3 0 AAA domain AAA_13 PF13166.6 KIY68755.1 - 0.02 13.6 0.0 2 6.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 KIY68755.1 - 0.024 13.8 0.6 2.6 7.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Roc PF08477.13 KIY68755.1 - 0.028 14.6 0.0 11 6.3 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NB-ARC PF00931.22 KIY68755.1 - 0.029 13.6 0.0 5.1 6.2 0.0 2.7 3 0 0 3 3 3 0 NB-ARC domain AAA_24 PF13479.6 KIY68755.1 - 0.042 13.6 3.5 2.4 7.8 0.0 2.9 4 0 0 4 4 3 0 AAA domain CLP1_P PF16575.5 KIY68755.1 - 0.049 13.4 1.4 14 5.5 0.0 3.3 3 0 0 3 3 3 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_5 PF07728.14 KIY68755.1 - 0.049 13.6 4.6 18 5.3 0.1 4.5 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) TsaE PF02367.17 KIY68755.1 - 0.071 13.1 0.0 17 5.4 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 KIY68755.1 - 0.078 13.0 0.1 12 6.0 0.1 3.5 3 1 0 3 3 3 0 AAA domain Dynamin_N PF00350.23 KIY68755.1 - 0.083 12.9 0.0 1.2 9.2 0.0 2.4 2 0 0 2 2 2 0 Dynamin family U3snoRNP10 PF12397.8 KIY68755.1 - 0.083 13.2 1.1 0.33 11.3 1.1 2.1 1 1 0 1 1 1 0 U3 small nucleolar RNA-associated protein 10 NTPase_1 PF03266.15 KIY68755.1 - 0.09 12.7 0.0 11 5.9 0.0 2.6 2 0 0 2 2 2 0 NTPase FtsK_SpoIIIE PF01580.18 KIY68755.1 - 0.12 11.8 0.1 2 7.7 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family cobW PF02492.19 KIY68755.1 - 0.25 10.9 1.7 15 5.2 0.1 3.2 4 0 0 4 4 3 0 CobW/HypB/UreG, nucleotide-binding domain HEAT PF02985.22 KIY68755.1 - 1.3 9.5 5.7 8.3 7.0 0.0 4.5 5 0 0 5 5 3 0 HEAT repeat Biotin_lipoyl PF00364.22 KIY68756.1 - 7.3e-12 45.0 0.1 1.1e-11 44.4 0.1 1.3 1 0 0 1 1 1 1 Biotin-requiring enzyme BTB PF00651.31 KIY68758.1 - 0.00032 20.9 0.0 0.00064 19.9 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KIY68759.1 - 0.0017 18.6 0.0 0.0041 17.3 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KIY68760.1 - 0.0012 19.0 0.0 0.003 17.8 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain DUF4293 PF14126.6 KIY68761.1 - 0.0012 19.1 1.3 0.0012 19.1 1.3 2.2 1 1 0 2 2 2 1 Domain of unknown function (DUF4293) Methyltransf_23 PF13489.6 KIY68762.1 - 1.7e-17 63.7 0.1 2.4e-17 63.3 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIY68762.1 - 3.1e-17 63.0 0.1 5.8e-17 62.2 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIY68762.1 - 1.6e-16 60.4 0.0 2e-16 60.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIY68762.1 - 3.9e-15 56.3 0.0 6.1e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIY68762.1 - 6e-11 43.0 0.0 9.5e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 KIY68762.1 - 3.3e-06 26.3 0.0 3.9e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_32 PF13679.6 KIY68762.1 - 4.5e-06 26.7 0.0 5.3e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KIY68762.1 - 1.7e-05 24.4 0.0 2.3e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.19 KIY68762.1 - 2.7e-05 24.4 0.0 3.4e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 KIY68762.1 - 9.7e-05 21.8 0.0 0.00033 20.1 0.0 1.8 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family NodS PF05401.11 KIY68762.1 - 0.00032 20.4 0.0 0.00052 19.7 0.0 1.4 1 1 0 1 1 1 1 Nodulation protein S (NodS) MetW PF07021.12 KIY68762.1 - 0.00051 19.7 0.0 0.0011 18.6 0.0 1.5 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW RrnaAD PF00398.20 KIY68762.1 - 0.001 18.2 0.0 0.0014 17.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase CMAS PF02353.20 KIY68762.1 - 0.0024 17.2 0.0 0.0029 17.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.13 KIY68762.1 - 0.0028 17.1 0.0 0.0033 16.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_33 PF10017.9 KIY68762.1 - 0.0043 16.3 0.3 0.71 9.0 0.0 2.1 1 1 1 2 2 2 2 Histidine-specific methyltransferase, SAM-dependent NMT1 PF09084.11 KIY68762.1 - 0.0066 16.4 0.0 0.011 15.7 0.0 1.4 1 1 0 1 1 1 1 NMT1/THI5 like Methyltransf_15 PF09445.10 KIY68762.1 - 0.011 15.4 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase AdoMet_MTase PF07757.13 KIY68762.1 - 0.013 15.8 0.0 0.023 15.0 0.0 1.4 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase TPMT PF05724.11 KIY68762.1 - 0.02 14.5 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) DREV PF05219.12 KIY68762.1 - 0.048 12.7 0.0 0.071 12.2 0.0 1.4 1 1 0 1 1 1 0 DREV methyltransferase PCMT PF01135.19 KIY68762.1 - 0.054 13.2 0.0 0.086 12.6 0.0 1.3 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TMIE PF16038.5 KIY68763.1 - 0.05 13.4 0.3 0.074 12.9 0.3 1.2 1 0 0 1 1 1 0 TMIE protein HemY_N PF07219.13 KIY68763.1 - 0.059 13.6 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 HemY protein N-terminus Shisa PF13908.6 KIY68763.1 - 0.094 12.9 1.1 0.21 11.8 0.0 1.9 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator DUF3437 PF11919.8 KIY68763.1 - 0.13 12.2 0.2 0.3 11.0 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3437) Tmemb_9 PF05434.11 KIY68763.1 - 0.16 11.9 0.0 0.23 11.3 0.0 1.1 1 0 0 1 1 1 0 TMEM9 TnpW PF14202.6 KIY68763.1 - 0.18 11.6 0.0 0.36 10.7 0.0 1.5 1 0 0 1 1 1 0 Transposon-encoded protein TnpW C_GCAxxG_C_C PF09719.10 KIY68763.1 - 0.2 11.9 0.0 0.28 11.5 0.0 1.2 1 0 0 1 1 1 0 Putative redox-active protein (C_GCAxxG_C_C) DUF5305 PF17231.2 KIY68763.1 - 0.3 10.5 0.0 0.42 10.0 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Orf78 PF06024.12 KIY68763.1 - 0.36 11.2 0.8 0.74 10.1 0.7 1.5 1 1 0 1 1 1 0 Orf78 (ac78) HMG_box PF00505.19 KIY68764.1 - 2.9e-07 30.8 5.2 6.7e-07 29.6 5.2 1.6 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KIY68764.1 - 0.00071 20.1 1.3 0.00091 19.8 1.3 1.2 1 0 0 1 1 1 1 HMG-box domain Glyoxalase_3 PF13468.6 KIY68765.1 - 6.2e-28 98.1 0.0 8.5e-28 97.6 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Cerato-platanin PF07249.12 KIY68766.1 - 3.5e-33 114.2 1.9 4e-33 114.0 1.9 1.0 1 0 0 1 1 1 1 Cerato-platanin Barwin PF00967.17 KIY68766.1 - 0.027 14.3 0.5 0.049 13.5 0.5 1.6 1 1 0 1 1 1 0 Barwin family Ccdc124 PF06244.12 KIY68769.1 - 9.8e-29 100.5 13.3 9.8e-29 100.5 13.3 2.2 2 1 0 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 Calcipressin PF04847.12 KIY68770.1 - 1.6e-31 109.5 0.0 2.5e-31 108.9 0.0 1.3 1 1 0 1 1 1 1 Calcipressin F-box-like PF12937.7 KIY68771.1 - 8.3e-09 35.2 0.4 2.7e-08 33.6 0.4 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY68771.1 - 0.0018 18.1 0.1 0.0071 16.2 0.1 2.1 1 0 0 1 1 1 1 F-box domain F-box-like_2 PF13013.6 KIY68771.1 - 0.093 12.7 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 F-box-like domain TRI5 PF06330.11 KIY68773.1 - 2.2e-16 59.7 0.0 2.9e-16 59.3 0.0 1.1 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) TRI5 PF06330.11 KIY68774.1 - 2.6e-08 33.1 0.0 2.9e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) GCP_N_terminal PF17681.1 KIY68774.1 - 0.061 12.9 0.0 0.09 12.4 0.0 1.2 1 0 0 1 1 1 0 Gamma tubulin complex component N-terminal Per1 PF04080.13 KIY68776.1 - 5.9e-95 317.9 8.4 7.1e-95 317.6 8.4 1.1 1 0 0 1 1 1 1 Per1-like family Ceramidase PF05875.12 KIY68776.1 - 0.12 11.7 8.9 4.9 6.5 8.9 2.1 1 1 0 1 1 1 0 Ceramidase Pectate_lyase_3 PF12708.7 KIY68777.1 - 3.7e-95 317.8 18.8 1.4e-82 276.7 10.4 2.8 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 KIY68777.1 - 4.4e-05 23.1 6.5 0.038 13.7 0.1 3.4 3 0 0 3 3 3 2 N terminal extension of bacteriophage endosialidase PP2C PF00481.21 KIY68778.1 - 9.1e-27 94.3 0.0 1.4e-26 93.7 0.0 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KIY68778.1 - 7.4e-06 25.7 0.0 3e-05 23.8 0.0 2.0 2 1 0 2 2 2 1 Protein phosphatase 2C SpoIIE PF07228.12 KIY68778.1 - 0.0069 16.3 0.0 0.12 12.3 0.0 2.2 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) Sugar_tr PF00083.24 KIY68779.1 - 1.2e-77 261.7 36.9 1.5e-77 261.4 36.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY68779.1 - 5.1e-26 91.4 45.1 7.1e-23 81.1 34.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily NmrA PF05368.13 KIY68783.1 - 9.8e-20 71.1 0.1 6.3e-18 65.2 0.0 2.3 1 1 1 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.6 KIY68783.1 - 6.3e-07 29.5 0.0 0.0052 16.7 0.0 2.8 1 1 1 2 2 2 2 NAD(P)H-binding NmrA PF05368.13 KIY68784.1 - 1.8e-28 99.7 0.0 2.1e-28 99.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KIY68784.1 - 2.8e-08 33.8 0.1 1.1e-07 31.9 0.1 1.9 1 1 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KIY68784.1 - 1e-06 29.1 0.7 2e-06 28.1 0.6 1.6 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KIY68784.1 - 0.0019 17.7 0.1 0.0033 16.9 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KIY68784.1 - 0.0068 16.3 0.2 0.012 15.6 0.2 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KIY68784.1 - 0.0073 15.5 0.3 0.011 14.9 0.3 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DapB_N PF01113.20 KIY68784.1 - 0.0088 16.2 0.3 0.018 15.2 0.3 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.25 KIY68784.1 - 0.028 13.9 0.1 0.045 13.2 0.1 1.3 1 0 0 1 1 1 0 short chain dehydrogenase 3Beta_HSD PF01073.19 KIY68784.1 - 0.031 13.3 0.8 0.045 12.7 0.3 1.5 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KIY68784.1 - 0.059 12.5 0.0 0.094 11.9 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein Semialdhyde_dh PF01118.24 KIY68784.1 - 0.14 12.6 0.2 0.26 11.7 0.2 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Furin-like_2 PF15913.5 KIY68785.1 - 3.2e-07 30.5 15.6 3.2e-07 30.5 15.6 6.9 2 1 5 7 7 7 3 Furin-like repeat, cysteine-rich VSP PF03302.13 KIY68785.1 - 0.00024 20.1 162.7 0.0079 15.1 12.1 6.6 1 1 5 6 6 6 5 Giardia variant-specific surface protein EGF_2 PF07974.13 KIY68785.1 - 0.0024 18.2 13.1 0.0024 18.2 13.1 12.7 12 4 0 12 12 12 2 EGF-like domain Laminin_EGF PF00053.24 KIY68785.1 - 0.014 15.5 21.2 0.014 15.5 21.2 9.8 2 2 6 8 8 8 0 Laminin EGF domain DUF4381 PF14316.6 KIY68785.1 - 0.023 14.9 0.8 0.041 14.1 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) MBOAT_2 PF13813.6 KIY68786.1 - 1.4e-18 66.9 5.0 1.4e-18 66.9 5.0 2.3 3 0 0 3 3 3 1 Membrane bound O-acyl transferase family SNARE_assoc PF09335.11 KIY68786.1 - 0.051 14.1 3.4 5.9 7.4 1.1 2.5 2 0 0 2 2 2 0 SNARE associated Golgi protein MBOAT_2 PF13813.6 KIY68787.1 - 1.6e-20 73.2 3.7 3.2e-20 72.2 3.7 1.5 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family DUF1600 PF07667.11 KIY68787.1 - 0.043 14.0 0.7 3.4 7.9 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1600) F-box PF00646.33 KIY68788.1 - 0.00053 19.8 0.1 0.036 14.0 0.0 2.9 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KIY68788.1 - 0.0011 18.8 0.0 0.0028 17.5 0.0 1.8 1 0 0 1 1 1 1 F-box-like SnoaL_2 PF12680.7 KIY68789.1 - 3.2e-05 24.5 0.1 6.1e-05 23.6 0.0 1.4 2 0 0 2 2 2 1 SnoaL-like domain Ada3 PF10198.9 KIY68790.1 - 1.8e-24 86.4 0.3 1.8e-24 86.4 0.3 3.0 3 1 0 3 3 3 1 Histone acetyltransferases subunit 3 OmpH PF03938.14 KIY68790.1 - 1.8 8.9 11.4 0.5 10.7 3.2 2.7 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) F-box-like PF12937.7 KIY68791.1 - 0.032 14.1 0.1 0.11 12.4 0.0 2.1 2 0 0 2 2 2 0 F-box-like tRNA-synt_1b PF00579.25 KIY68792.1 - 4.7e-72 242.8 0.0 5.8e-72 242.5 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) tRNA-synt_1f PF01921.18 KIY68792.1 - 0.065 12.1 0.0 0.51 9.2 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (K) Mak10 PF04112.13 KIY68793.1 - 5.5e-49 165.9 0.0 9.8e-49 165.1 0.0 1.4 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase DUF3079 PF11278.8 KIY68793.1 - 0.052 13.4 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3079) p450 PF00067.22 KIY68796.1 - 1.8e-62 211.6 0.0 4.7e-62 210.3 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 TRI5 PF06330.11 KIY68797.1 - 7e-09 35.0 0.0 7.8e-09 34.9 0.0 1.0 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) TRI5 PF06330.11 KIY68798.1 - 1.1e-14 54.1 0.0 1.8e-14 53.4 0.0 1.3 1 1 0 1 1 1 1 Trichodiene synthase (TRI5) Transket_pyr PF02779.24 KIY68799.1 - 1.2e-64 217.2 0.0 1.9e-64 216.6 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 KIY68799.1 - 3.4e-60 203.5 0.0 4.9e-60 203.0 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 KIY68799.1 - 2.3e-52 176.7 0.0 4.1e-52 175.9 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 KIY68799.1 - 1.5e-17 62.9 0.5 3e-17 61.9 0.5 1.5 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus PH PF00169.29 KIY68800.1 - 7.3e-13 48.9 0.1 9.4e-13 48.6 0.1 1.1 1 0 0 1 1 1 1 PH domain PBD PF00786.28 KIY68800.1 - 2e-08 34.5 0.3 3.9e-08 33.5 0.3 1.5 1 0 0 1 1 1 1 P21-Rho-binding domain PH_11 PF15413.6 KIY68800.1 - 0.00021 21.7 0.5 0.0006 20.2 0.5 1.8 1 1 0 1 1 1 1 Pleckstrin homology domain Pkinase PF00069.25 KIY68803.1 - 1e-21 77.5 0.0 1.4e-10 41.0 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIY68803.1 - 5.1e-09 35.8 0.0 0.0029 16.9 0.0 2.7 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIY68803.1 - 4.9e-05 22.3 0.0 0.1 11.3 0.0 2.1 1 1 1 2 2 2 2 Fungal protein kinase APH PF01636.23 KIY68803.1 - 0.003 17.5 2.7 0.43 10.4 1.3 2.8 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 KIY68803.1 - 0.16 11.3 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HSP70 PF00012.20 KIY68804.1 - 7.7e-79 265.5 7.3 7.7e-79 265.5 7.3 3.0 2 1 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 KIY68804.1 - 0.0002 20.3 0.5 0.00042 19.2 0.5 1.6 1 1 0 1 1 1 1 MreB/Mbl protein BcrAD_BadFG PF01869.20 KIY68804.1 - 0.001 18.6 0.1 0.0024 17.4 0.1 1.6 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family ADH_zinc_N_2 PF13602.6 KIY68804.1 - 0.098 13.7 0.1 2.4 9.2 0.0 2.7 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Aminotran_3 PF00202.21 KIY68805.1 - 1.5e-94 317.0 0.0 1.7e-94 316.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KIY68805.1 - 7e-05 22.2 0.0 0.00012 21.4 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class I and II DUF3533 PF12051.8 KIY68806.1 - 6.2e-87 292.0 19.7 7.2e-87 291.8 19.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) ABC2_membrane_3 PF12698.7 KIY68806.1 - 1.5e-07 30.9 21.5 2e-07 30.5 21.5 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein Nup84_Nup100 PF04121.13 KIY68807.1 - 1.2e-126 423.7 0.0 3.8e-126 422.1 0.0 1.7 1 1 0 1 1 1 1 Nuclear pore protein 84 / 107 zf-MYND PF01753.18 KIY68808.1 - 5.8e-10 39.1 15.4 5.8e-10 39.1 15.4 4.6 3 1 0 3 3 3 1 MYND finger zf-C6H2 PF15801.5 KIY68808.1 - 0.0021 18.4 14.3 0.0021 18.4 14.3 3.7 3 1 1 4 4 4 1 zf-MYND-like zinc finger, mRNA-binding Senescence_reg PF04520.13 KIY68813.1 - 1.2 9.9 7.4 1.8 9.3 6.3 1.5 1 1 0 1 1 1 0 Senescence regulator RRM_1 PF00076.22 KIY68816.1 - 8.7e-12 44.7 0.1 1.4e-11 44.0 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TP2 PF01254.18 KIY68816.1 - 0.53 10.9 12.6 0.05 14.2 5.0 2.3 2 0 0 2 2 2 0 Nuclear transition protein 2 Citrate_synt PF00285.21 KIY68817.1 - 9.9e-98 327.5 0.0 1.2e-97 327.2 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Methyltransf_4 PF02390.17 KIY68818.1 - 4.7e-53 179.2 0.0 5.9e-53 178.9 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 KIY68818.1 - 0.00011 22.9 0.0 0.00068 20.3 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIY68818.1 - 0.0026 18.4 0.1 0.015 15.9 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 KIY68818.1 - 0.014 15.0 0.0 0.14 11.7 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase small domain Vault PF01505.18 KIY68818.1 - 0.051 13.7 0.3 0.88 9.8 0.0 2.3 2 0 0 2 2 2 0 Major Vault Protein repeat domain Methyltransf_12 PF08242.12 KIY68818.1 - 0.06 14.1 0.0 0.21 12.4 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.6 KIY68818.1 - 0.074 12.8 0.0 0.22 11.3 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Abhydrolase_1 PF00561.20 KIY68819.1 - 1.5e-14 54.3 0.0 2.2e-14 53.7 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIY68819.1 - 1.4e-09 38.9 0.1 1.8e-09 38.5 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIY68819.1 - 2.4e-09 36.8 0.0 4.8e-09 35.8 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 KIY68819.1 - 4.8e-05 23.3 0.3 0.22 11.3 0.0 2.5 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase Esterase PF00756.20 KIY68819.1 - 0.0022 17.7 0.0 0.0033 17.1 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Ndr PF03096.14 KIY68819.1 - 0.0064 15.2 0.0 0.01 14.6 0.0 1.2 1 0 0 1 1 1 1 Ndr family Peptidase_S9 PF00326.21 KIY68819.1 - 0.019 14.5 0.1 0.061 12.8 0.1 1.9 2 1 0 2 2 2 0 Prolyl oligopeptidase family SET PF00856.28 KIY68820.1 - 7.5e-13 49.2 0.0 1.2e-12 48.5 0.0 1.4 1 0 0 1 1 1 1 SET domain zf-MYND PF01753.18 KIY68820.1 - 3.1e-09 36.8 14.1 3.1e-09 36.8 14.1 3.3 2 1 0 2 2 2 1 MYND finger DHHC PF01529.20 KIY68821.1 - 1.7e-33 115.6 5.9 1.7e-33 115.6 5.9 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase HMG_CoA_synt_C PF08540.10 KIY68821.1 - 0.18 11.4 0.0 0.3 10.7 0.0 1.3 1 0 0 1 1 1 0 Hydroxymethylglutaryl-coenzyme A synthase C terminal DUF1772 PF08592.11 KIY68821.1 - 0.31 11.3 2.6 0.68 10.2 0.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF1772) FYVE PF01363.21 KIY68821.1 - 7.9 6.7 9.8 48 4.2 10.1 2.0 1 1 0 1 1 1 0 FYVE zinc finger HSF_DNA-bind PF00447.17 KIY68822.1 - 1.5e-22 80.0 0.0 2.4e-22 79.3 0.0 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding DUF179 PF02622.15 KIY68822.1 - 0.036 14.0 0.2 0.076 13.0 0.2 1.5 1 1 0 1 1 1 0 Uncharacterized ACR, COG1678 TMEM135_C_rich PF15982.5 KIY68823.1 - 5.7e-05 23.7 0.0 0.0002 22.0 0.0 1.9 2 0 0 2 2 2 1 N-terminal cysteine-rich region of Transmembrane protein 135 DHDPS PF00701.22 KIY68824.1 - 7.5e-42 143.0 0.0 9e-42 142.8 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Rad51 PF08423.11 KIY68825.1 - 0.0012 18.2 0.0 0.0022 17.3 0.0 1.4 1 1 0 1 1 1 1 Rad51 AAA_25 PF13481.6 KIY68825.1 - 0.0085 15.7 0.0 0.029 13.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain DUF5401 PF17380.2 KIY68826.1 - 0.0071 14.5 4.8 0.012 13.8 4.8 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5401) OrsD PF12013.8 KIY68826.1 - 0.014 15.8 1.3 0.07 13.6 0.0 2.2 2 0 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_jaz PF12171.8 KIY68826.1 - 0.036 14.4 0.0 0.079 13.3 0.0 1.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KIY68826.1 - 0.13 12.6 0.1 0.27 11.7 0.1 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KIY68826.1 - 0.16 12.3 0.0 0.27 11.6 0.0 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) CTU2 PF10288.9 KIY68826.1 - 0.46 10.7 4.1 0.16 12.2 0.3 2.0 2 0 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 PEARLI-4 PF05278.12 KIY68826.1 - 0.83 9.2 8.9 1.5 8.3 8.9 1.3 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) UbiA PF01040.18 KIY68827.1 - 9.2e-17 61.2 9.1 1.3e-16 60.6 9.1 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family DnaJ PF00226.31 KIY68828.1 - 2.5e-23 82.0 0.6 8.8e-23 80.2 0.6 2.0 1 0 0 1 1 1 1 DnaJ domain zf-met PF12874.7 KIY68828.1 - 1.6e-09 37.9 7.2 2.1e-08 34.3 1.0 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KIY68828.1 - 2.2e-08 34.1 5.5 3.7e-08 33.5 0.3 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 KIY68828.1 - 1.1e-06 28.7 3.7 0.025 15.0 0.6 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 KIY68828.1 - 3.6e-06 27.2 4.3 0.0099 16.2 0.2 3.0 3 0 0 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KIY68828.1 - 1.7e-05 25.3 2.3 0.094 13.6 0.1 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KIY68828.1 - 0.00015 21.7 5.8 0.001 19.0 0.5 2.4 2 0 0 2 2 2 1 C2H2-type zinc finger Phage_int_SAM_4 PF13495.6 KIY68828.1 - 0.031 14.7 0.4 12 6.5 0.0 2.8 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain zf-C2H2_3 PF13878.6 KIY68828.1 - 0.13 12.1 0.3 0.4 10.5 0.3 1.8 1 0 0 1 1 1 0 zinc-finger of acetyl-transferase ESCO zf-H2C2_2 PF13465.6 KIY68828.1 - 0.17 12.4 0.1 36 5.0 0.0 2.7 2 0 0 2 2 2 0 Zinc-finger double domain CTU2 PF10288.9 KIY68828.1 - 6.7 7.0 7.8 9.1 6.6 0.9 2.9 3 0 0 3 3 3 0 Cytoplasmic tRNA 2-thiolation protein 2 zf-Tim10_DDP PF02953.15 KIY68829.1 - 9.6e-18 63.6 0.7 1.4e-17 63.1 0.7 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger FANCI_S3 PF14677.6 KIY68829.1 - 0.063 13.0 0.1 0.073 12.8 0.1 1.2 1 0 0 1 1 1 0 FANCI solenoid 3 DUF2116 PF09889.9 KIY68829.1 - 0.11 12.5 0.1 0.18 11.8 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Homeodomain PF00046.29 KIY68830.1 - 8.7e-19 67.1 2.9 1.6e-18 66.3 2.9 1.4 1 0 0 1 1 1 1 Homeodomain U1snRNP70_N PF12220.8 KIY68831.1 - 3.5e-24 85.2 3.3 6e-24 84.5 3.3 1.4 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.22 KIY68831.1 - 3.2e-17 62.1 0.0 5.1e-17 61.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KIY68831.1 - 0.053 13.1 0.0 0.08 12.5 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UbiA PF01040.18 KIY68832.1 - 2.5e-52 177.7 22.5 3.3e-52 177.3 22.5 1.0 1 0 0 1 1 1 1 UbiA prenyltransferase family SID-1_RNA_chan PF13965.6 KIY68832.1 - 0.076 11.4 0.0 0.12 10.8 0.0 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 p450 PF00067.22 KIY68833.1 - 3.8e-63 213.9 0.0 9.4e-63 212.5 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 P22_AR_C PF10548.9 KIY68833.1 - 0.058 13.6 0.1 0.37 11.0 0.0 2.1 2 0 0 2 2 2 0 P22AR C-terminal domain Oxidored_molyb PF00174.19 KIY68834.1 - 5.3e-55 185.7 0.0 7.9e-55 185.1 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 KIY68834.1 - 2.7e-16 59.8 0.4 5.3e-16 58.9 0.4 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain COX6B PF02297.17 KIY68835.1 - 8.6e-20 70.8 5.5 1e-19 70.5 5.5 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CX9C PF16860.5 KIY68835.1 - 0.072 13.1 1.1 0.11 12.5 1.1 1.3 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Prp18 PF02840.15 KIY68836.1 - 2.2e-61 206.1 0.1 2.2e-61 206.1 0.1 1.7 2 0 0 2 2 2 1 Prp18 domain PRP4 PF08799.11 KIY68836.1 - 4.2e-12 45.4 4.6 9.6e-12 44.2 3.6 2.2 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like Pinin_SDK_memA PF04696.13 KIY68836.1 - 0.018 15.1 12.1 0.051 13.6 10.0 2.6 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region SRP-alpha_N PF04086.13 KIY68836.1 - 2.2 8.1 8.4 3.4 7.5 8.4 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal p450 PF00067.22 KIY68837.1 - 1.3e-60 205.5 0.0 2.2e-60 204.7 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Oxidored_molyb PF00174.19 KIY68838.1 - 9.6e-57 191.3 0.0 1.4e-56 190.8 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 KIY68838.1 - 2.6e-13 50.2 1.9 5e-13 49.3 1.9 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Pro_isomerase PF00160.21 KIY68839.1 - 3.5e-43 147.6 0.0 5.5e-43 147.0 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ras PF00071.22 KIY68840.1 - 1.7e-49 167.5 0.1 1.9e-49 167.4 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIY68840.1 - 5.6e-21 75.0 0.0 7.9e-21 74.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 KIY68840.1 - 3.6e-06 27.0 0.7 0.0035 17.3 0.1 2.2 1 1 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KIY68840.1 - 1.5e-05 24.6 0.2 0.00012 21.6 0.2 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Septin PF00735.18 KIY68840.1 - 0.00017 21.0 0.0 0.42 9.8 0.0 2.1 2 0 0 2 2 2 2 Septin MMR_HSR1 PF01926.23 KIY68840.1 - 0.0002 21.4 0.1 0.00034 20.7 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF2075 PF09848.9 KIY68840.1 - 0.0075 15.6 0.4 1.6 7.9 0.1 2.1 1 1 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) ImcF-related_N PF14331.6 KIY68840.1 - 0.025 13.9 0.0 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 ImcF-related N-terminal domain AAA_16 PF13191.6 KIY68840.1 - 0.031 14.7 0.0 0.038 14.4 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KIY68840.1 - 0.042 14.1 0.1 0.57 10.5 0.1 2.3 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KIY68840.1 - 0.043 14.0 0.1 0.12 12.5 0.0 1.7 1 1 1 2 2 2 0 AAA domain AAA_25 PF13481.6 KIY68840.1 - 0.095 12.3 0.0 0.22 11.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain CbiA PF01656.23 KIY68840.1 - 0.66 10.0 2.6 20 5.3 2.6 2.1 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain DEAD PF00270.29 KIY68841.1 - 7.5e-52 175.6 0.0 5.2e-51 172.9 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIY68841.1 - 7.3e-32 110.0 0.0 2e-30 105.4 0.0 2.5 2 1 1 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIY68841.1 - 2.1e-08 34.3 0.0 5e-08 33.1 0.0 1.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KIY68841.1 - 0.0021 17.8 0.0 0.028 14.1 0.0 2.4 1 1 0 1 1 1 1 AAA domain UTP25 PF06862.12 KIY68841.1 - 0.011 14.6 0.0 0.41 9.4 0.0 2.4 2 1 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 MFS_1 PF07690.16 KIY68842.1 - 1.3e-31 109.8 44.5 3.9e-29 101.7 37.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Dynamin_N PF00350.23 KIY68843.1 - 4.3e-42 144.0 0.1 1.3e-41 142.5 0.0 1.9 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.20 KIY68843.1 - 2.2e-09 37.0 0.0 1.1e-08 34.6 0.0 2.2 3 0 0 3 3 3 1 Dynamin central region MMR_HSR1 PF01926.23 KIY68843.1 - 0.00015 21.9 0.0 0.00051 20.1 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase ApoO PF09769.9 KIY68843.1 - 0.088 12.8 0.2 0.43 10.5 0.0 2.1 2 0 0 2 2 2 0 Apolipoprotein O AAA_16 PF13191.6 KIY68843.1 - 0.16 12.4 0.4 1.4 9.2 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_15 PF13175.6 KIY68843.1 - 0.23 11.1 1.8 0.86 9.2 0.1 2.2 2 0 0 2 2 2 0 AAA ATPase domain DUF883 PF05957.13 KIY68843.1 - 0.32 11.6 3.4 3.1 8.5 0.0 3.4 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 KIY68843.1 - 1.5 9.4 5.3 11 6.7 0.0 3.8 4 1 0 4 4 4 0 YtxH-like protein Glyco_hydro_18 PF00704.28 KIY68844.1 - 1.3e-24 87.5 4.2 4e-24 85.9 4.1 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 DUF4188 PF13826.6 KIY68844.1 - 0.061 13.7 0.0 0.13 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4188) SCP2 PF02036.17 KIY68846.1 - 2.2e-24 85.8 1.2 2.9e-24 85.5 1.2 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 KIY68846.1 - 5.5e-07 29.9 0.5 6.7e-07 29.6 0.5 1.2 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal SCP2_2 PF13530.6 KIY68846.1 - 0.0074 16.7 0.1 0.0089 16.4 0.1 1.1 1 0 0 1 1 1 1 Sterol carrier protein domain TLP1_add_C PF18313.1 KIY68846.1 - 0.05 13.6 0.1 1.7 8.6 0.1 2.2 1 1 1 2 2 2 0 Thiolase-like protein type 1 additional C-terminal domain Serinc PF03348.15 KIY68847.1 - 9.7e-161 535.5 13.3 1.1e-160 535.3 13.3 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) Aconitase PF00330.20 KIY68848.1 - 2.3e-109 366.4 0.1 2.4e-108 363.1 0.1 2.1 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KIY68848.1 - 9.6e-20 71.2 0.1 2.7e-19 69.8 0.1 1.8 1 1 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.13 KIY68848.1 - 0.089 11.5 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF521) DUF5068 PF16781.5 KIY68848.1 - 0.089 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5068) Aldolase_II PF00596.21 KIY68849.1 - 2.4e-42 145.0 0.3 3e-42 144.6 0.3 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Tox-MPTase4 PF15640.6 KIY68849.1 - 0.062 13.2 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Metallopeptidase toxin 4 TauD PF02668.16 KIY68850.1 - 6.4e-37 127.8 0.0 9.2e-37 127.3 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 KIY68850.1 - 3.6e-17 62.8 0.1 6.8e-17 61.9 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF971) CsiD PF08943.10 KIY68850.1 - 0.0011 18.1 0.1 0.0065 15.6 0.0 1.9 2 0 0 2 2 2 1 CsiD POTRA_2 PF08479.11 KIY68851.1 - 0.22 11.4 0.0 0.43 10.5 0.0 1.4 1 0 0 1 1 1 0 POTRA domain, ShlB-type PI3Ka PF00613.20 KIY68853.1 - 2.2e-54 183.7 0.2 3.5e-54 183.0 0.2 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 KIY68853.1 - 5.9e-46 157.3 0.0 9.2e-32 110.8 0.0 2.3 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 KIY68853.1 - 1.3e-38 132.1 0.0 2.3e-38 131.2 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 DnaJ PF00226.31 KIY68854.1 - 1.2e-15 57.4 0.2 2.6e-15 56.3 0.2 1.6 1 0 0 1 1 1 1 DnaJ domain cobW PF02492.19 KIY68855.1 - 4.4e-38 130.6 0.0 6.4e-38 130.1 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 KIY68855.1 - 0.011 15.7 0.0 0.021 14.8 0.0 1.4 1 0 0 1 1 1 0 Cobalamin synthesis protein cobW C-terminal domain DUF1574 PF07611.11 KIY68855.1 - 0.023 14.1 0.0 0.029 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1574) Adaptin_N PF01602.20 KIY68856.1 - 6.6e-97 325.2 0.0 1e-96 324.6 0.0 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KIY68856.1 - 3.6e-13 49.9 0.7 1.2e-12 48.1 0.1 2.3 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KIY68856.1 - 0.008 16.5 6.6 0.3 11.5 0.0 4.5 3 2 1 4 4 4 1 HEAT repeats HEAT PF02985.22 KIY68856.1 - 0.024 14.9 0.6 6.7 7.3 0.0 4.0 3 0 0 3 3 3 0 HEAT repeat Nop14 PF04147.12 KIY68856.1 - 7.7 4.6 14.1 13 3.8 14.1 1.3 1 0 0 1 1 1 0 Nop14-like family Frag1 PF10277.9 KIY68857.1 - 7.4e-32 110.7 6.3 7.4e-32 110.7 6.3 3.2 3 0 0 3 3 3 2 Frag1/DRAM/Sfk1 family OPT PF03169.15 KIY68861.1 - 6.9e-128 427.9 52.1 8e-128 427.7 52.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Peptidase_M20 PF01546.28 KIY68862.1 - 7.7e-35 120.5 0.0 1.4e-34 119.7 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KIY68862.1 - 2e-11 43.7 0.0 6.1e-11 42.2 0.0 1.9 1 1 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KIY68862.1 - 0.091 12.4 0.0 0.38 10.4 0.0 1.9 1 1 0 1 1 1 0 Peptidase family M28 R3H PF01424.22 KIY68862.1 - 0.1 12.6 0.1 0.56 10.2 0.0 2.2 2 0 0 2 2 2 0 R3H domain HECT PF00632.25 KIY68863.1 - 4.2e-82 276.1 0.0 6e-82 275.6 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Arm PF00514.23 KIY68863.1 - 0.02 15.0 8.3 0.29 11.2 0.0 5.2 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat UIM PF02809.20 KIY68863.1 - 0.06 13.3 0.2 0.33 11.0 0.2 2.3 1 0 0 1 1 1 0 Ubiquitin interaction motif Nse4-Nse3_bdg PF15412.6 KIY68863.1 - 0.074 13.2 0.8 0.36 11.0 0.1 2.5 2 0 0 2 2 2 0 Binding domain of Nse4/EID3 to Nse3-MAGE Ribosomal_S4e PF00900.20 KIY68866.1 - 3.5e-36 123.0 0.1 8.9e-36 121.7 0.1 1.7 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.5 KIY68866.1 - 3.1e-27 93.9 0.0 5.4e-27 93.2 0.0 1.4 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 KIY68866.1 - 5.1e-22 77.7 4.0 4e-21 74.8 5.4 1.8 2 0 0 2 2 2 1 RS4NT (NUC023) domain KOW PF00467.29 KIY68866.1 - 3.3e-06 26.9 1.3 3.3e-06 26.9 1.3 2.1 2 0 0 2 2 2 1 KOW motif S4 PF01479.25 KIY68866.1 - 0.00094 18.9 1.3 0.00098 18.8 0.2 1.6 2 0 0 2 2 2 1 S4 domain DUF1287 PF06940.11 KIY68866.1 - 0.12 12.0 0.1 0.32 10.6 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1287) ComC PF03047.14 KIY68866.1 - 0.19 11.5 0.1 0.38 10.6 0.1 1.4 1 0 0 1 1 1 0 COMC family DUF2781 PF10914.8 KIY68867.1 - 6.5e-37 127.2 15.1 7.5e-37 127.0 15.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) F-box-like PF12937.7 KIY68868.1 - 5e-09 35.9 1.1 1e-08 34.9 1.1 1.5 1 0 0 1 1 1 1 F-box-like TPT PF03151.16 KIY68869.1 - 3.2e-56 190.8 23.0 3.9e-56 190.5 23.0 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KIY68869.1 - 7.3e-12 45.6 28.5 9.1e-07 29.1 12.3 2.5 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 KIY68869.1 - 2.6e-09 36.7 22.1 3.2e-09 36.4 22.1 1.1 1 0 0 1 1 1 1 UAA transporter family PSII PF00421.19 KIY68869.1 - 0.025 13.3 1.1 0.036 12.7 0.1 1.7 2 0 0 2 2 2 0 Photosystem II protein TMEM100 PF16311.5 KIY68869.1 - 0.55 9.8 6.6 0.4 10.3 0.1 2.9 3 0 0 3 3 3 0 Transmembrane protein 100 Multi_Drug_Res PF00893.19 KIY68869.1 - 4.1 8.1 10.6 4.1 8.1 1.1 3.5 3 0 0 3 3 3 0 Small Multidrug Resistance protein CRAL_TRIO PF00650.20 KIY68870.1 - 1.2e-25 90.1 0.0 1.7e-25 89.6 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KIY68870.1 - 2.8e-05 24.2 0.2 7.3e-05 22.9 0.0 1.8 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KIY68870.1 - 0.17 12.1 0.1 0.32 11.1 0.1 1.4 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain DAO PF01266.24 KIY68871.1 - 1.7e-07 31.1 0.0 2e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Fe-ADH PF00465.19 KIY68873.1 - 2.1e-90 303.2 0.0 2.7e-90 302.8 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 KIY68873.1 - 6.9e-12 45.6 0.0 8.2e-07 29.0 0.0 2.3 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Ribosomal_L37ae PF01780.19 KIY68876.1 - 1.2e-41 140.7 11.3 1.4e-41 140.5 11.3 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-RING_13 PF17977.1 KIY68876.1 - 0.00029 20.9 1.0 0.00041 20.4 1.0 1.2 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Zn_Tnp_IS1595 PF12760.7 KIY68876.1 - 0.002 18.1 1.6 0.0033 17.4 1.6 1.4 1 0 0 1 1 1 1 Transposase zinc-ribbon domain zf-FCS PF06467.14 KIY68876.1 - 0.014 15.3 2.3 0.83 9.6 0.2 2.3 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif A2L_zn_ribbon PF08792.10 KIY68876.1 - 0.11 12.2 3.3 5.4 6.9 0.1 2.2 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-BED PF02892.15 KIY68876.1 - 0.17 11.9 4.1 5.3 7.2 0.3 2.2 1 1 1 2 2 2 0 BED zinc finger zf-H2C2_2 PF13465.6 KIY68876.1 - 0.25 11.8 3.9 1.7 9.2 0.9 2.3 1 1 1 2 2 2 0 Zinc-finger double domain C1_2 PF03107.16 KIY68876.1 - 0.36 11.2 2.5 1.2 9.5 2.5 1.8 1 1 0 1 1 1 0 C1 domain RabGAP-TBC PF00566.18 KIY68877.1 - 3.4e-50 170.7 0.0 5.2e-50 170.1 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain APG6_N PF17675.1 KIY68877.1 - 0.14 12.6 2.8 0.13 12.8 1.2 1.7 2 0 0 2 2 2 0 Apg6 coiled-coil region BAF1_ABF1 PF04684.13 KIY68877.1 - 0.17 10.9 0.5 0.29 10.2 0.5 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Muted PF14942.6 KIY68877.1 - 0.44 10.9 2.1 3 8.2 0.2 2.2 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein GST_N PF02798.20 KIY68878.1 - 7.8e-15 55.0 0.0 1.6e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KIY68878.1 - 1e-14 54.5 0.0 1.7e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KIY68878.1 - 1.6e-11 44.4 0.0 2.8e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KIY68878.1 - 3.1e-07 30.5 0.0 5.5e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KIY68878.1 - 4.6e-07 30.1 0.0 1e-06 28.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KIY68878.1 - 1.8e-05 24.7 0.1 3.4e-05 23.8 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Cu-oxidase PF00394.22 KIY68879.1 - 5.2e-47 159.9 0.0 5.3e-44 150.1 0.0 3.0 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 KIY68879.1 - 2e-37 128.0 6.3 2.5e-34 117.9 0.1 3.8 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KIY68879.1 - 3.4e-37 127.1 1.9 2.7e-35 120.9 0.2 3.5 4 0 0 4 4 4 1 Multicopper oxidase GH3 PF03321.13 KIY68879.1 - 0.31 9.9 0.0 0.42 9.4 0.0 1.1 1 0 0 1 1 1 0 GH3 auxin-responsive promoter DnaJ PF00226.31 KIY68880.1 - 2.1e-10 40.6 0.2 1.2e-09 38.2 0.0 2.2 2 0 0 2 2 2 1 DnaJ domain DUF2371 PF10177.9 KIY68880.1 - 0.088 13.0 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) Beta_helix PF13229.6 KIY68883.1 - 2.9 7.7 6.7 1.9 8.3 1.8 2.8 2 1 0 2 2 2 0 Right handed beta helix region Abhydrolase_1 PF00561.20 KIY68884.1 - 7.7e-43 147.0 0.0 1.6e-42 146.0 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIY68884.1 - 0.019 15.6 3.8 0.031 14.9 3.8 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Paf1 PF03985.13 KIY68885.1 - 9.9e-69 232.4 1.0 1.2e-68 232.1 1.0 1.1 1 0 0 1 1 1 1 Paf1 adh_short_C2 PF13561.6 KIY68887.1 - 5.7e-40 137.3 0.1 6.6e-40 137.1 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIY68887.1 - 4.3e-35 121.0 0.0 5.2e-35 120.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIY68887.1 - 1e-12 48.4 0.0 2.1e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KIY68887.1 - 0.00011 21.7 0.0 0.0002 20.9 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.8 KIY68887.1 - 0.00082 19.1 0.1 1 9.1 0.0 2.4 2 0 0 2 2 2 2 NAD(P)H binding domain of trans-2-enoyl-CoA reductase RmlD_sub_bind PF04321.17 KIY68887.1 - 0.0023 17.1 0.0 0.0034 16.5 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 KIY68887.1 - 0.0028 17.6 0.0 0.0059 16.5 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding Bactofilin PF04519.13 KIY68887.1 - 0.0044 17.3 0.2 0.031 14.5 0.1 2.2 2 0 0 2 2 2 1 Polymer-forming cytoskeletal GDP_Man_Dehyd PF16363.5 KIY68887.1 - 0.0089 15.5 0.0 0.043 13.2 0.0 1.8 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase DUF1776 PF08643.10 KIY68887.1 - 0.043 13.2 0.0 0.064 12.6 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) NmrA PF05368.13 KIY68887.1 - 0.053 13.1 0.1 0.086 12.4 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family Esterase_phd PF10503.9 KIY68888.1 - 0.0024 17.4 0.3 0.014 14.9 0.3 2.2 1 1 1 2 2 2 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 KIY68888.1 - 0.01 15.3 0.2 0.076 12.5 0.2 2.1 1 1 1 2 2 2 0 Prolyl oligopeptidase family Esterase PF00756.20 KIY68888.1 - 0.019 14.6 0.0 0.044 13.4 0.0 1.5 2 0 0 2 2 2 0 Putative esterase Sof1 PF04158.14 KIY68889.1 - 8.2e-27 93.3 9.1 1.6e-26 92.4 9.1 1.5 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.32 KIY68889.1 - 1.4e-22 79.5 11.5 7.3e-08 33.0 0.2 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat Pectinesterase PF01095.19 KIY68890.1 - 1.9e-36 125.3 7.1 2.4e-36 125.0 7.1 1.0 1 0 0 1 1 1 1 Pectinesterase ssDBP PF17878.1 KIY68890.1 - 0.16 12.2 1.3 0.57 10.4 0.1 2.4 2 0 0 2 2 2 0 Single-stranded DNA-binding protein Zip PF02535.22 KIY68891.1 - 0.76 8.9 2.9 0.81 8.8 2.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Hid1 PF12722.7 KIY68891.1 - 1.1 7.3 4.0 1.2 7.2 4.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein WD40 PF00400.32 KIY68892.1 - 2.7e-06 28.0 7.1 0.58 11.1 0.1 5.2 4 1 0 4 4 4 3 WD domain, G-beta repeat CPSF_A PF03178.15 KIY68892.1 - 0.057 12.7 0.0 1.4 8.2 0.0 2.2 2 0 0 2 2 2 0 CPSF A subunit region Nup160 PF11715.8 KIY68892.1 - 0.057 12.1 0.0 0.17 10.5 0.0 1.7 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Cyclin_N PF00134.23 KIY68893.1 - 5.7e-40 136.0 0.3 2.2e-39 134.1 0.1 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KIY68893.1 - 8.4e-10 38.8 0.2 1.9e-09 37.6 0.2 1.6 1 1 0 1 1 1 1 Cyclin, C-terminal domain Med3 PF11593.8 KIY68893.1 - 0.064 12.4 0.7 0.093 11.9 0.7 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal RSV_NS2 PF03113.14 KIY68893.1 - 0.18 11.8 0.0 0.34 11.0 0.0 1.3 1 0 0 1 1 1 0 Respiratory synctial virus non-structural protein NS2 Aldedh PF00171.22 KIY68894.1 - 4.5e-18 65.0 2.2 2.6e-15 55.9 0.3 2.1 2 0 0 2 2 2 2 Aldehyde dehydrogenase family URO-D PF01208.17 KIY68894.1 - 0.012 14.8 0.0 0.021 14.0 0.0 1.3 1 0 0 1 1 1 0 Uroporphyrinogen decarboxylase (URO-D) SHNi-TPR PF10516.9 KIY68895.1 - 3e-15 55.4 0.1 6.1e-14 51.2 0.0 2.4 2 0 0 2 2 2 1 SHNi-TPR TPR_12 PF13424.6 KIY68895.1 - 1.3e-12 47.9 5.4 2.4e-05 24.5 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KIY68895.1 - 1.3e-07 31.1 0.0 0.003 17.3 0.3 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 KIY68895.1 - 2.2e-06 27.5 1.1 0.013 15.7 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KIY68895.1 - 6.7e-06 25.8 4.7 0.025 14.7 0.8 3.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 KIY68895.1 - 0.00012 21.7 0.4 0.019 14.6 0.2 3.2 2 1 0 2 2 2 1 TPR repeat TPR_16 PF13432.6 KIY68895.1 - 0.00013 22.5 2.2 0.12 13.1 1.0 3.4 2 2 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 KIY68895.1 - 0.002 17.9 0.0 0.68 9.9 0.0 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 KIY68895.1 - 0.011 15.7 0.1 0.84 9.8 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4693 PF15764.5 KIY68895.1 - 0.041 13.5 0.1 0.061 12.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4693) TPR_14 PF13428.6 KIY68895.1 - 0.08 13.8 2.4 12 7.0 0.2 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 KIY68895.1 - 0.23 12.0 2.8 10 6.7 0.1 3.6 2 1 1 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 KIY68895.1 - 0.3 11.2 0.1 0.3 11.2 0.1 3.0 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain BRO1 PF03097.18 KIY68896.1 - 2.6e-14 52.8 0.0 4.4e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 BRO1-like domain dsDNA_bind PF01984.20 KIY68897.1 - 6.3e-28 97.3 2.2 6.8e-28 97.2 2.2 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain TetR_C_11 PF16859.5 KIY68897.1 - 0.0074 16.6 3.5 0.01 16.2 3.5 1.1 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain PCI PF01399.27 KIY68897.1 - 0.13 12.8 0.0 0.17 12.4 0.0 1.2 1 0 0 1 1 1 0 PCI domain TFIIA PF03153.13 KIY68898.1 - 2.9 7.8 14.8 4.9 7.0 14.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Methyltransf_25 PF13649.6 KIY68899.1 - 4e-11 43.5 0.1 6.9e-11 42.7 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIY68899.1 - 1.8e-10 41.3 0.0 3.2e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIY68899.1 - 9.4e-10 38.5 0.0 1.3e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIY68899.1 - 0.015 15.2 0.0 0.021 14.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 KIY68899.1 - 0.043 13.1 0.0 0.065 12.6 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 KIY68899.1 - 0.046 13.7 0.0 0.065 13.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.12 KIY68899.1 - 0.059 12.9 0.0 0.096 12.3 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW MTS PF05175.14 KIY68899.1 - 0.14 11.6 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Glyco_hydro_47 PF01532.20 KIY68900.1 - 2.2e-128 429.1 0.0 2.6e-128 428.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF4407 PF14362.6 KIY68900.1 - 0.13 11.6 2.9 0.21 10.9 2.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FGGY_N PF00370.21 KIY68901.1 - 1e-61 208.6 0.0 1.1e-29 103.8 0.0 2.3 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 KIY68901.1 - 3.4e-61 206.4 2.0 5.1e-61 205.9 2.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain ANTH PF07651.16 KIY68903.1 - 2.4e-51 174.3 0.0 3.3e-51 173.9 0.0 1.2 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.20 KIY68903.1 - 0.012 15.7 0.0 0.022 14.8 0.0 1.4 1 0 0 1 1 1 0 ENTH domain DUF1720 PF08226.11 KIY68903.1 - 0.013 15.9 5.3 0.013 15.9 5.3 7.3 2 2 2 6 6 6 0 Domain of unknown function (DUF1720) APG17 PF04108.12 KIY68904.1 - 5.8e-70 236.4 15.9 6.6e-70 236.2 15.9 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 DUF4201 PF13870.6 KIY68904.1 - 0.01 15.6 0.1 0.01 15.6 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4201) OKR_DC_1_N PF03709.15 KIY68904.1 - 0.056 13.7 0.3 0.25 11.7 0.1 2.2 2 0 0 2 2 2 0 Orn/Lys/Arg decarboxylase, N-terminal domain DUF2664 PF10867.8 KIY68904.1 - 0.058 13.8 0.8 0.058 13.8 0.8 3.3 4 0 0 4 4 3 0 Protein of unknown function (DUF2664) Cor1 PF04803.12 KIY68904.1 - 0.061 13.5 0.1 0.061 13.5 0.1 3.0 3 0 0 3 3 3 0 Cor1/Xlr/Xmr conserved region Stimulus_sens_1 PF13756.6 KIY68904.1 - 0.24 12.0 2.1 0.67 10.6 0.5 2.6 2 0 0 2 2 2 0 Stimulus-sensing domain Spectrin_like PF18373.1 KIY68904.1 - 0.47 10.5 10.4 0.26 11.4 1.6 3.8 3 1 1 4 4 4 0 Spectrin like domain Glutaredoxin2_C PF04399.13 KIY68904.1 - 0.48 10.3 3.2 5.9 6.7 0.0 3.6 3 1 1 4 4 4 0 Glutaredoxin 2, C terminal domain KxDL PF10241.9 KIY68904.1 - 0.51 10.6 6.4 2.8 8.3 0.0 3.6 4 0 0 4 4 4 0 Uncharacterized conserved protein Vir_act_alpha_C PF10400.9 KIY68904.1 - 1.6 9.4 8.2 8.7 7.1 0.4 3.6 3 0 0 3 3 3 0 Virulence activator alpha C-term Synaptonemal_3 PF15191.6 KIY68904.1 - 2 8.2 7.7 6.6 6.6 0.6 3.1 3 0 0 3 3 3 0 Synaptonemal complex central element protein 3 NPV_P10 PF05531.12 KIY68904.1 - 2 8.9 9.1 3.4 8.2 0.5 4.0 3 2 1 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 KIY68904.1 - 3.8 7.6 11.9 4.6 7.3 1.0 4.4 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) FF PF01846.19 KIY68905.1 - 1.7e-34 117.7 3.5 1.6e-12 47.4 0.0 6.2 6 0 0 6 6 6 5 FF domain WW PF00397.26 KIY68905.1 - 1.6e-12 47.2 17.0 4.7e-06 26.6 6.1 2.6 2 0 0 2 2 2 2 WW domain Kei1 PF08552.11 KIY68906.1 - 2.8e-47 161.1 4.4 3.9e-47 160.6 4.4 1.2 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 IF4E PF01652.18 KIY68907.1 - 2.5e-54 183.4 0.0 2.9e-54 183.1 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E EthD PF07110.11 KIY68908.1 - 1.2e-10 42.4 0.2 1.6e-10 42.0 0.2 1.2 1 0 0 1 1 1 1 EthD domain BBS2_N PF14781.6 KIY68908.1 - 0.021 14.7 0.0 0.029 14.3 0.0 1.2 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, N-terminal MmlI PF09448.10 KIY68908.1 - 0.04 14.4 0.0 0.082 13.4 0.0 1.4 1 1 0 1 1 1 0 Methylmuconolactone methyl-isomerase SRF-TF PF00319.18 KIY68908.1 - 0.076 12.5 0.1 0.23 11.0 0.3 1.7 2 0 0 2 2 2 0 SRF-type transcription factor (DNA-binding and dimerisation domain) EthD PF07110.11 KIY68909.1 - 3.4e-13 50.6 0.7 4.1e-13 50.3 0.7 1.1 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 KIY68909.1 - 3.2e-05 24.3 0.1 4.3e-05 23.9 0.1 1.1 1 0 0 1 1 1 1 Methylmuconolactone methyl-isomerase DUF3489 PF11994.8 KIY68909.1 - 0.032 14.3 0.0 0.059 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3489) vATP-synt_AC39 PF01992.16 KIY68909.1 - 0.056 12.9 0.0 0.056 12.9 0.0 1.2 1 0 0 1 1 1 0 ATP synthase (C/AC39) subunit MBOAT_2 PF13813.6 KIY68910.1 - 1.6e-10 41.1 1.6 3e-10 40.2 1.6 1.5 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Glyco_hydro_61 PF03443.14 KIY68911.1 - 2.7e-46 158.1 0.0 3.3e-46 157.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 YL1 PF05764.13 KIY68912.1 - 0.0039 17.4 9.8 0.0056 16.8 9.8 1.3 1 0 0 1 1 1 1 YL1 nuclear protein CDC45 PF02724.14 KIY68912.1 - 0.045 12.1 9.9 0.059 11.7 9.9 1.1 1 0 0 1 1 1 0 CDC45-like protein eIF3_subunit PF08597.10 KIY68912.1 - 0.68 9.8 12.6 0.91 9.4 12.6 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Glyco_hydro_71 PF03659.14 KIY68913.1 - 5.3e-119 397.4 0.1 6.1e-119 397.2 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Ribosomal_L21p PF00829.21 KIY68914.1 - 2.7e-26 91.8 0.9 3.2e-26 91.5 0.9 1.1 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein UvrA_inter PF17760.1 KIY68914.1 - 0.0058 16.7 0.0 0.0087 16.1 0.0 1.3 1 0 0 1 1 1 1 UvrA interaction domain CAMSAP_CC1 PF17095.5 KIY68914.1 - 0.14 12.0 1.1 0.21 11.4 1.1 1.3 1 0 0 1 1 1 0 Spectrin-binding region of Ca2+-Calmodulin ATP-synt_ab PF00006.25 KIY68915.1 - 3.6e-73 245.8 0.0 5e-73 245.3 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 KIY68915.1 - 4.3e-43 146.6 0.1 7.3e-43 145.9 0.1 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 KIY68915.1 - 1.5e-17 63.8 0.8 4.1e-17 62.5 0.8 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain F-box-like PF12937.7 KIY68916.1 - 5.6e-09 35.8 3.6 1e-08 34.9 1.5 2.6 2 0 0 2 2 2 1 F-box-like HMG_box PF00505.19 KIY68917.1 - 0.026 14.9 0.1 0.08 13.4 0.1 1.8 1 1 0 1 1 1 0 HMG (high mobility group) box MATalpha_HMGbox PF04769.12 KIY68917.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 HMG-box adh_short_C2 PF13561.6 KIY68918.1 - 5.1e-44 150.6 0.4 1.5e-42 145.7 0.4 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIY68918.1 - 9.6e-39 132.9 0.5 2e-38 131.8 0.5 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIY68918.1 - 3.7e-05 23.7 0.5 0.0001 22.3 0.1 1.8 2 0 0 2 2 2 1 KR domain 3HCDH_N PF02737.18 KIY68918.1 - 0.019 14.9 2.1 0.034 14.0 0.7 2.1 2 1 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glyco_hydro_18 PF00704.28 KIY68919.1 - 2.8e-55 188.2 5.2 3.5e-55 187.9 5.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 PX PF00787.24 KIY68919.1 - 2.1e-11 43.8 0.0 4.3e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 PX domain GHL15 PF14885.6 KIY68919.1 - 0.015 15.3 0.2 0.025 14.6 0.2 1.3 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase family 15 GEMIN8 PF15348.6 KIY68920.1 - 0.68 10.2 8.3 0.8 10.0 8.3 1.1 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 Fungal_trans PF04082.18 KIY68921.1 - 2.8e-11 43.0 0.1 5.6e-11 42.0 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY68921.1 - 0.00014 21.9 7.8 0.00023 21.2 7.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIIA PF03153.13 KIY68921.1 - 0.32 10.9 24.5 0.33 10.9 14.3 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Pkinase PF00069.25 KIY68923.1 - 2.4e-42 145.1 0.0 2.6e-42 145.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY68923.1 - 4.7e-20 72.0 0.0 5.9e-20 71.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KIY68923.1 - 1.6e-05 24.9 0.1 5e-05 23.3 0.1 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KIY68923.1 - 5.9e-05 22.5 0.0 7.7e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KIY68923.1 - 0.005 15.8 0.0 0.0071 15.3 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 KIY68923.1 - 0.0089 15.1 0.1 0.013 14.6 0.1 1.1 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.14 KIY68923.1 - 0.078 12.3 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KIY68923.1 - 0.15 11.6 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.25 KIY68924.1 - 6.6e-47 160.1 0.0 8.4e-47 159.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY68924.1 - 8.1e-25 87.6 0.0 1.2e-24 87.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIY68924.1 - 0.00017 20.5 0.4 0.00032 19.6 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KIY68924.1 - 0.00036 20.5 2.2 0.066 13.1 0.0 3.1 2 1 0 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 KIY68924.1 - 0.0063 15.9 0.0 0.0098 15.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PBAN PF05874.11 KIY68924.1 - 0.026 14.4 0.3 0.14 12.0 0.0 2.1 2 0 0 2 2 2 0 Pheromone biosynthesis activating neuropeptide (PBAN) Kinase-like PF14531.6 KIY68924.1 - 0.05 12.9 0.0 0.083 12.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Seadorna_VP7 PF07387.11 KIY68924.1 - 0.079 12.0 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 zf-H2C2_5 PF13909.6 KIY68930.1 - 2.5e-06 27.1 20.6 0.041 13.6 0.0 5.7 6 0 0 6 6 6 4 C2H2-type zinc-finger domain ssDBP PF17878.1 KIY68930.1 - 0.14 12.4 1.6 6.4 7.1 0.4 2.4 2 0 0 2 2 2 0 Single-stranded DNA-binding protein zf-C2H2_jaz PF12171.8 KIY68930.1 - 0.33 11.3 0.2 0.33 11.3 0.2 2.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 KIY68930.1 - 9.5 6.9 24.0 0.36 11.3 0.6 5.6 6 0 0 6 6 6 0 Zinc-finger double domain DUF2706 PF10913.8 KIY68931.1 - 0.082 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2706) GGACT PF06094.12 KIY68932.1 - 2.6e-18 66.8 0.0 3.3e-18 66.5 0.0 1.1 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like SARS_lipid_bind PF09399.10 KIY68932.1 - 0.14 12.3 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 SARS lipid binding protein Catalase PF00199.19 KIY68934.1 - 7.4e-176 584.9 0.1 9.5e-176 584.5 0.1 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 KIY68934.1 - 1e-15 57.6 0.0 2.3e-15 56.5 0.0 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive CHB_HEX_C_1 PF13290.6 KIY68934.1 - 0.025 14.6 0.0 0.075 13.1 0.0 1.8 1 0 0 1 1 1 0 Chitobiase/beta-hexosaminidase C-terminal domain Fn3_assoc PF13287.6 KIY68934.1 - 0.053 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Fn3 associated DUF4903 PF16246.5 KIY68934.1 - 0.15 11.7 0.0 0.32 10.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4903) MFS_1 PF07690.16 KIY68935.1 - 3e-20 72.4 20.8 4.4e-20 71.9 20.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Pkinase PF00069.25 KIY68940.1 - 8.7e-49 166.2 0.0 1.1e-48 165.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY68940.1 - 1e-26 93.8 0.0 1.4e-26 93.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KIY68940.1 - 0.00076 19.5 0.0 0.0016 18.4 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KIY68940.1 - 0.081 12.2 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 KIY68940.1 - 0.094 12.1 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1264 PF06884.11 KIY68941.1 - 0.069 12.7 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1264) Pkinase PF00069.25 KIY68942.1 - 1e-41 143.0 0.0 1.6e-41 142.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY68942.1 - 6e-23 81.4 0.0 8.2e-23 81.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KIY68942.1 - 0.00013 22.0 0.0 0.00022 21.2 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KIY68942.1 - 0.00042 19.7 0.0 0.00058 19.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KIY68942.1 - 0.052 12.9 0.0 0.11 11.8 0.0 1.5 1 1 0 1 1 1 0 Kinase-like Haspin_kinase PF12330.8 KIY68942.1 - 0.1 11.5 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain CRAL_TRIO PF00650.20 KIY68943.1 - 1e-24 87.0 0.0 1.4e-24 86.6 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KIY68943.1 - 1.2e-09 38.2 0.0 2.2e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KIY68943.1 - 0.0026 17.9 0.0 0.0037 17.4 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain zf-H2C2_5 PF13909.6 KIY68944.1 - 3.4e-06 26.7 0.1 8.4e-06 25.4 0.1 1.7 1 0 0 1 1 1 1 C2H2-type zinc-finger domain Pho86 PF11124.8 KIY68944.1 - 0.04 13.4 0.0 0.046 13.2 0.0 1.1 1 0 0 1 1 1 0 Inorganic phosphate transporter Pho86 OrsD PF12013.8 KIY68944.1 - 0.066 13.7 2.3 0.31 11.5 0.1 2.5 1 1 2 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-H2C2_5 PF13909.6 KIY68945.1 - 1.1e-05 25.1 28.1 0.02 14.6 0.6 6.6 7 0 0 7 7 7 3 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 KIY68945.1 - 0.012 16.1 0.8 0.012 16.1 0.8 6.4 7 0 0 7 7 7 0 Zinc finger, C2H2 type DUF1192 PF06698.11 KIY68945.1 - 0.014 15.5 0.6 0.036 14.1 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) zf_C2H2_ZHX PF18387.1 KIY68945.1 - 0.052 13.2 22.1 7.9 6.2 0.0 5.6 3 3 3 6 6 6 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_aberr PF17017.5 KIY68945.1 - 0.077 13.1 3.4 0.1 12.8 0.3 2.3 2 0 0 2 2 2 0 Aberrant zinc-finger DNA_pol_phi PF04931.13 KIY68945.1 - 2.3 6.2 5.8 3.1 5.8 5.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi zf-met PF12874.7 KIY68945.1 - 3.3 8.2 10.7 8.8 6.9 0.0 4.1 4 0 0 4 4 4 0 Zinc-finger of C2H2 type DUF1936 PF09151.10 KIY68945.1 - 3.5 7.6 5.8 14 5.7 0.3 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1936) OrsD PF12013.8 KIY68945.1 - 7.8 7.0 30.2 3.3 8.2 0.6 6.7 4 2 3 7 7 7 0 Orsellinic acid/F9775 biosynthesis cluster protein D PEMT PF04191.13 KIY68946.1 - 1.5e-47 160.3 14.6 7.2e-27 93.9 0.1 4.0 5 0 0 5 5 5 2 Phospholipid methyltransferase HECW_N PF16562.5 KIY68946.1 - 0.082 12.7 0.1 0.18 11.6 0.1 1.5 1 0 0 1 1 1 0 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 ICMT PF04140.14 KIY68947.1 - 5e-15 55.7 1.1 6.2e-14 52.2 1.1 2.5 1 1 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KIY68947.1 - 1.6e-09 38.1 0.8 1.1e-08 35.4 0.8 2.2 1 1 0 1 1 1 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 KIY68947.1 - 0.0001 21.2 0.0 0.00014 20.7 0.0 1.4 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 KIY68947.1 - 0.026 14.0 0.1 0.039 13.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) DUF2232 PF09991.9 KIY68947.1 - 0.036 13.2 0.5 0.036 13.2 0.5 2.1 1 1 0 2 2 2 0 Predicted membrane protein (DUF2232) Sugar_tr PF00083.24 KIY68948.1 - 3.3e-38 131.7 18.7 4.7e-38 131.2 18.7 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY68948.1 - 6e-31 107.7 32.1 6e-31 107.7 32.1 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Mucin PF01456.17 KIY68949.1 - 0.55 10.2 8.2 1 9.3 8.2 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Sugar_tr PF00083.24 KIY68950.1 - 7.8e-98 328.3 23.0 9.1e-98 328.0 23.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY68950.1 - 2.3e-21 76.1 22.0 2.3e-21 76.1 22.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3562 PF12085.8 KIY68955.1 - 0.032 13.9 0.0 0.068 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3562) Mlo PF03094.15 KIY68955.1 - 0.076 11.4 0.0 0.11 10.8 0.0 1.2 1 0 0 1 1 1 0 Mlo family Rot1 PF10681.9 KIY68956.1 - 1.6e-37 129.1 3.7 1.8e-37 128.9 3.7 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal Bmp PF02608.14 KIY68956.1 - 0.063 12.2 0.0 0.085 11.8 0.0 1.1 1 0 0 1 1 1 0 ABC transporter substrate-binding protein PnrA-like NICE-1 PF15845.5 KIY68957.1 - 0.038 14.8 0.7 0.096 13.5 0.7 1.7 1 0 0 1 1 1 0 Cysteine-rich C-terminal 1 family F-box-like_2 PF13013.6 KIY68958.1 - 0.017 15.1 0.0 5.4 7.0 0.0 2.4 2 0 0 2 2 2 0 F-box-like domain Phage_holin_5_2 PF16079.5 KIY68960.1 - 7.1 7.0 7.0 5.2 7.5 0.0 2.6 2 1 1 3 3 3 0 Phage holin family Hol44, in holin superfamily V CDKN3 PF05706.12 KIY68961.1 - 0.064 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) RIO1 PF01163.22 KIY68962.1 - 0.092 12.3 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 KIY68962.1 - 0.13 12.2 1.5 2.2 8.1 0.1 2.8 2 1 1 3 3 3 0 Phosphotransferase enzyme family NST1 PF13945.6 KIY68969.1 - 2.5e-49 168.0 0.0 2.5e-49 168.0 0.0 3.2 2 1 1 3 3 3 1 Salt tolerance down-regulator Nop14 PF04147.12 KIY68969.1 - 1.3e-06 27.0 35.0 0.00019 19.9 24.2 2.1 2 0 0 2 2 2 2 Nop14-like family Paf1 PF03985.13 KIY68969.1 - 0.0074 15.3 1.8 0.0074 15.3 1.8 3.1 3 0 0 3 3 3 1 Paf1 BUD22 PF09073.10 KIY68969.1 - 0.037 13.4 40.7 0.31 10.4 4.9 2.3 2 0 0 2 2 2 0 BUD22 SDA1 PF05285.12 KIY68969.1 - 1.6 8.1 51.6 2.4 7.5 8.4 2.5 2 0 0 2 2 2 0 SDA1 PCM1_C PF15717.5 KIY68971.1 - 0.037 12.7 1.8 0.037 12.7 1.8 1.1 1 0 0 1 1 1 0 Pericentriolar material 1 C terminus MFS_1 PF07690.16 KIY68972.1 - 8.4e-42 143.4 24.4 8.4e-42 143.4 24.4 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIY68972.1 - 1.4e-08 34.1 6.5 3.4e-08 32.8 6.5 1.6 1 0 0 1 1 1 1 Sugar (and other) transporter CE2_N PF17996.1 KIY68973.1 - 4.6e-07 29.8 0.1 0.013 15.5 0.1 2.4 2 0 0 2 2 2 2 Carbohydrate esterase 2 N-terminal DUF5640 PF18692.1 KIY68973.1 - 0.055 13.5 0.1 16 5.6 0.0 2.7 2 1 0 2 2 2 0 Family of unknown function (DUF5640) SWM_repeat PF13753.6 KIY68973.1 - 0.1 12.8 0.2 14 5.9 0.0 3.6 2 2 2 4 4 4 0 Putative flagellar system-associated repeat Glyco_hydro_61 PF03443.14 KIY68975.1 - 9.3e-26 91.0 0.0 1.4e-25 90.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Nop14 PF04147.12 KIY68975.1 - 4.9 5.2 10.0 6.5 4.8 10.0 1.0 1 0 0 1 1 1 0 Nop14-like family SpoIIIAH PF12685.7 KIY68975.1 - 5 6.9 10.3 7.8 6.3 10.3 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein DUF908 PF06012.12 KIY68975.1 - 7 6.0 9.4 12 5.2 9.4 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Thaumatin PF00314.17 KIY68976.1 - 4.5e-67 225.8 7.6 5.1e-67 225.6 7.6 1.0 1 0 0 1 1 1 1 Thaumatin family WD40 PF00400.32 KIY68977.1 - 1.5e-21 76.2 3.4 9e-05 23.2 0.0 7.2 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY68977.1 - 2.2e-12 47.1 0.3 0.00063 20.0 0.0 5.1 4 1 1 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIY68977.1 - 9.7e-05 22.3 0.1 0.072 13.0 0.1 3.1 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.14 KIY68977.1 - 0.00068 18.8 0.0 1.8 7.5 0.0 2.9 2 1 0 2 2 2 2 Coatomer WD associated region TFIIIC_delta PF12657.7 KIY68977.1 - 0.026 14.4 0.7 0.77 9.7 0.2 2.6 2 0 0 2 2 2 0 Transcription factor IIIC subunit delta N-term PD40 PF07676.12 KIY68977.1 - 0.051 13.5 1.2 6 6.9 0.0 4.0 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KIY68977.1 - 0.058 12.3 0.1 6.4 5.6 0.0 3.1 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Proteasome_A_N PF10584.9 KIY68977.1 - 0.16 11.7 0.3 40 4.0 0.1 3.3 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature BBS2_Mid PF14783.6 KIY68977.1 - 0.17 12.0 0.2 2.5 8.2 0.0 2.8 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region adh_short_C2 PF13561.6 KIY68978.1 - 2.4e-31 109.1 0.5 1.2e-30 106.8 0.5 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIY68978.1 - 4.9e-28 97.9 2.2 1.1e-27 96.7 0.1 2.4 2 1 0 2 2 2 1 short chain dehydrogenase adh_short PF00106.25 KIY68979.1 - 6.9e-38 130.1 0.2 8.9e-38 129.7 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIY68979.1 - 5.3e-36 124.4 0.3 1.1e-35 123.2 0.3 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIY68979.1 - 1.2e-06 28.6 0.7 1.2e-06 28.6 0.7 1.8 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KIY68979.1 - 0.025 14.0 0.1 1.8 8.0 0.1 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 KIY68979.1 - 0.12 12.2 0.4 0.26 11.2 0.4 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KIY68979.1 - 0.24 11.4 1.3 0.76 9.8 0.9 1.8 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase FHA PF00498.26 KIY68980.1 - 4.1e-09 36.6 0.0 7.7e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 FHA domain FTA4 PF13093.6 KIY68980.1 - 0.0021 18.0 3.4 0.024 14.5 3.4 2.1 1 1 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 TPR_MLP1_2 PF07926.12 KIY68980.1 - 0.044 13.8 14.6 0.38 10.8 10.9 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein HalX PF08663.10 KIY68980.1 - 0.16 12.3 0.0 0.16 12.3 0.0 2.9 3 1 1 4 4 4 0 HalX domain DUF724 PF05266.14 KIY68980.1 - 0.48 10.2 10.3 0.3 10.9 7.8 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Baculo_PEP_C PF04513.12 KIY68980.1 - 0.7 9.9 4.0 2.5 8.1 1.9 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2203 PF09969.9 KIY68980.1 - 1.6 9.5 8.0 0.85 10.3 2.7 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Spectrin PF00435.21 KIY68980.1 - 2.1 8.9 10.7 0.91 10.0 0.7 2.7 1 1 1 2 2 2 0 Spectrin repeat Spc7 PF08317.11 KIY68980.1 - 3 6.6 13.7 8 5.2 13.4 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein FliD_N PF02465.18 KIY68980.1 - 3.1 8.6 6.0 11 6.8 1.3 2.7 1 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus APG6_N PF17675.1 KIY68980.1 - 7 7.2 18.6 2.5 8.6 0.7 2.3 1 1 2 3 3 3 0 Apg6 coiled-coil region DUF4200 PF13863.6 KIY68980.1 - 7.2 7.0 12.6 2.6 8.5 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Cytochrom_B562 PF07361.11 KIY68980.1 - 9.2 7.0 8.9 12 6.6 4.4 2.4 1 1 1 2 2 2 0 Cytochrome b562 Thaumatin PF00314.17 KIY68981.1 - 7.8e-69 231.6 8.7 8.9e-69 231.4 8.7 1.0 1 0 0 1 1 1 1 Thaumatin family PQQ PF01011.21 KIY68981.1 - 0.046 13.7 0.1 0.12 12.3 0.1 1.7 1 0 0 1 1 1 0 PQQ enzyme repeat Ribosomal_L27e PF01777.18 KIY68983.1 - 6.5e-36 122.5 3.6 1e-35 121.9 3.6 1.3 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 KIY68983.1 - 0.013 15.4 1.1 0.049 13.6 1.1 2.1 1 0 0 1 1 1 0 KOW motif Hydrophobin PF01185.18 KIY68984.1 - 2.9e-15 56.6 10.5 2.9e-15 56.6 10.5 1.5 2 0 0 2 2 2 1 Fungal hydrophobin Toxin_12 PF07740.12 KIY68984.1 - 1.4 9.7 8.3 17 6.2 1.4 3.0 2 0 0 2 2 2 0 Ion channel inhibitory toxin TFIIS_C PF01096.18 KIY68985.1 - 2.3e-10 40.1 2.3 2.3e-10 40.1 2.3 2.8 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 KIY68985.1 - 2.1e-08 33.9 9.2 3e-08 33.4 1.4 3.7 4 0 0 4 4 4 1 RNA polymerases M/15 Kd subunit Lar_restr_allev PF14354.6 KIY68985.1 - 0.0064 16.9 0.5 0.0064 16.9 0.5 2.4 2 1 0 2 2 2 1 Restriction alleviation protein Lar zf-ACC PF17848.1 KIY68985.1 - 0.04 14.0 5.1 24 5.1 0.1 4.0 4 0 0 4 4 4 0 Acetyl-coA carboxylase zinc finger domain CpXC PF14353.6 KIY68985.1 - 0.16 12.1 5.2 0.77 9.8 0.9 2.7 1 1 1 2 2 2 0 CpXC protein zf_UBZ PF18439.1 KIY68985.1 - 0.37 10.4 11.6 2.8 7.6 0.1 3.9 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_2 PF13240.6 KIY68985.1 - 0.86 9.4 8.1 0.87 9.4 0.1 3.5 3 0 0 3 3 3 0 zinc-ribbon domain zf-RRN7 PF11781.8 KIY68985.1 - 3 7.6 8.2 3.7 7.3 0.1 3.3 3 0 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zf-C2H2 PF00096.26 KIY68986.1 - 1.2e-10 41.3 10.6 4.8e-05 23.6 2.6 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIY68986.1 - 1.6e-08 34.7 7.5 0.00065 20.3 1.3 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KIY68986.1 - 1.4e-07 31.7 4.0 0.00077 19.8 0.2 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-met PF12874.7 KIY68986.1 - 8.6e-06 26.0 1.3 4.1e-05 23.8 0.3 2.5 2 1 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KIY68986.1 - 0.00011 22.4 2.0 0.0032 17.7 0.1 2.8 2 1 1 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KIY68986.1 - 0.00038 20.4 2.5 0.0032 17.4 0.3 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KIY68986.1 - 0.051 13.5 7.1 0.5 10.3 1.2 2.8 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-Di19 PF05605.12 KIY68986.1 - 0.11 12.8 1.5 14 6.1 0.0 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 KIY68988.1 - 1.4e-12 47.4 23.8 4.9e-05 23.6 0.1 5.2 5 0 0 5 5 5 3 Zinc-finger double domain zf-H2C2_5 PF13909.6 KIY68988.1 - 1.4e-07 31.1 16.8 0.0043 16.8 0.4 4.7 4 0 0 4 4 4 4 C2H2-type zinc-finger domain zf-Di19 PF05605.12 KIY68988.1 - 0.00021 21.5 2.1 0.00021 21.5 2.1 2.8 3 0 0 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 KIY68988.1 - 0.0048 17.6 20.7 0.011 16.5 0.4 4.6 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KIY68988.1 - 0.0074 16.7 26.2 0.38 11.3 0.7 4.9 5 0 0 5 5 5 3 Zinc finger, C2H2 type Zap1_zf2 PF18217.1 KIY68988.1 - 0.025 14.6 13.5 0.094 12.7 0.1 4.2 4 0 0 4 4 4 0 Zap1 zinc finger 2 FOXP-CC PF16159.5 KIY68988.1 - 2.3 8.9 22.3 4.5 8.0 0.3 4.6 2 1 3 5 5 5 0 FOXP coiled-coil domain KDZ PF18758.1 KIY68994.1 - 5.6e-48 163.5 0.6 9.6e-48 162.7 0.6 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KIY68994.1 - 2e-28 98.6 0.0 4.7e-28 97.5 0.0 1.6 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KIY68994.1 - 1.4e-06 28.4 0.0 4e-06 26.9 0.0 1.8 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases MukB PF04310.12 KIY68994.1 - 0.012 15.5 0.3 0.031 14.1 0.3 1.6 1 0 0 1 1 1 0 MukB N-terminal eIF-5_eIF-2B PF01873.17 KIY68998.1 - 8.1e-41 138.6 0.2 1.5e-40 137.8 0.2 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.12 KIY68998.1 - 0.001 18.5 0.2 0.0022 17.5 0.2 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding IF2_N PF04760.15 KIY68998.1 - 0.0086 15.9 0.0 0.024 14.5 0.0 1.7 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region zf-HYPF PF07503.12 KIY68998.1 - 0.091 12.6 0.1 18 5.2 0.0 2.4 2 0 0 2 2 2 0 HypF finger Arc_trans_TRASH PF08394.10 KIY68998.1 - 1.5 9.2 4.6 14 6.1 0.0 2.6 1 1 1 2 2 2 0 Archaeal TRASH domain ATP-synt PF00231.19 KIY68999.1 - 4.6e-77 259.5 2.2 5.1e-77 259.3 2.2 1.0 1 0 0 1 1 1 1 ATP synthase OmpA PF00691.20 KIY68999.1 - 0.18 12.2 1.5 1.1 9.7 0.2 2.8 4 0 0 4 4 4 0 OmpA family Glyco_hydro_28 PF00295.17 KIY69001.1 - 1.6e-67 227.9 12.4 1.9e-67 227.6 12.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Cadherin_5 PF17892.1 KIY69001.1 - 0.0079 16.2 3.1 0.051 13.5 0.1 2.9 2 1 0 2 2 2 1 Cadherin-like domain Hexokinase_2 PF03727.16 KIY69002.1 - 2.5e-82 275.9 0.0 3.4e-82 275.5 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KIY69002.1 - 5.7e-69 232.0 0.0 8e-69 231.5 0.0 1.2 1 0 0 1 1 1 1 Hexokinase FGGY_N PF00370.21 KIY69002.1 - 0.1 12.2 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain Ribosomal_L14 PF00238.19 KIY69003.1 - 5.8e-45 152.3 1.3 6.5e-45 152.2 1.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Fungal_trans PF04082.18 KIY69004.1 - 5e-16 58.5 0.8 8.2e-16 57.8 0.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY69004.1 - 1.4e-07 31.5 8.9 1.4e-07 31.5 8.9 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3673 PF12425.8 KIY69004.1 - 0.13 12.2 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3673) Pkinase_Tyr PF07714.17 KIY69009.1 - 4.1e-37 127.9 0.0 5.1e-37 127.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIY69009.1 - 5.5e-35 121.0 0.0 7.3e-35 120.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KIY69009.1 - 0.0021 16.9 0.0 0.0028 16.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase GMC_oxred_N PF00732.19 KIY69010.1 - 8.4e-31 107.4 0.0 1.2e-30 106.9 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIY69010.1 - 3.3e-25 89.3 0.0 9.1e-25 87.9 0.0 1.8 2 0 0 2 2 2 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 KIY69010.1 - 3.7e-05 23.1 0.0 0.0046 16.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIY69010.1 - 0.0019 18.4 3.2 0.011 16.0 1.6 3.0 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KIY69010.1 - 0.038 13.6 3.5 0.75 9.3 1.9 2.9 3 0 0 3 3 3 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KIY69010.1 - 0.041 13.0 2.1 0.2 10.7 0.9 2.1 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.6 KIY69010.1 - 0.041 13.1 0.1 1.1 8.4 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pro_isomerase PF00160.21 KIY69011.1 - 3.1e-45 154.3 0.1 4.7e-45 153.7 0.1 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.17 KIY69011.1 - 9.2e-06 25.4 9.6 0.0071 16.4 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KIY69011.1 - 1.1e-05 25.1 1.5 0.016 15.0 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 KIY69011.1 - 0.0067 16.7 0.4 4.2 7.7 0.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KIY69011.1 - 0.013 16.1 2.3 3.4 8.4 0.1 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 KIY69011.1 - 0.067 12.9 1.7 7.4 6.3 0.1 2.8 2 1 1 3 3 3 0 TPR repeat TPR_6 PF13174.6 KIY69011.1 - 0.35 11.6 4.6 3.3 8.5 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Aminotran_4 PF01063.19 KIY69012.1 - 2.7e-28 99.4 0.0 3.6e-28 99.0 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV tRNA_U5-meth_tr PF05958.11 KIY69013.1 - 1.1e-17 64.1 0.0 4.4e-17 62.1 0.0 1.8 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_15 PF09445.10 KIY69013.1 - 1.1e-06 28.3 0.0 2e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Cons_hypoth95 PF03602.15 KIY69013.1 - 2.4e-06 27.3 0.0 4.3e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_25 PF13649.6 KIY69013.1 - 3.8e-06 27.5 0.1 1.3e-05 25.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIY69013.1 - 5.1e-06 26.4 0.0 8.4e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KIY69013.1 - 5.8e-06 25.9 0.0 1e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 KIY69013.1 - 0.0021 18.7 0.0 0.0082 16.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIY69013.1 - 0.005 17.6 0.0 0.025 15.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 KIY69013.1 - 0.0058 16.1 0.0 0.0095 15.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) TRM PF02005.16 KIY69013.1 - 0.018 14.2 0.0 0.031 13.4 0.0 1.3 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase Exo_endo_phos PF03372.23 KIY69014.1 - 6.3e-07 29.1 0.0 1.5e-06 27.9 0.1 1.6 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family INPP5B_PH PF16776.5 KIY69014.1 - 7.2e-05 22.5 0.3 0.0086 15.8 0.0 2.6 3 0 0 3 3 3 2 Type II inositol 1,4,5-trisphosphate 5-phosphatase PH domain HABP4_PAI-RBP1 PF04774.15 KIY69015.1 - 6.4e-05 23.8 1.0 8.9e-05 23.3 1.0 1.2 1 0 0 1 1 1 1 Hyaluronan / mRNA binding family Sugar_tr PF00083.24 KIY69016.1 - 2.3e-14 53.1 18.7 1.9e-13 50.1 18.7 2.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY69016.1 - 1.5e-12 47.1 47.4 5.3e-07 28.9 16.1 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2583 PF10762.9 KIY69016.1 - 0.28 11.6 2.6 0.27 11.7 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2583) MoCF_biosynth PF00994.24 KIY69017.1 - 6.6e-34 116.6 0.0 1.3e-33 115.7 0.0 1.5 1 0 0 1 1 1 1 Probable molybdopterin binding domain Sugar-bind PF04198.13 KIY69017.1 - 0.028 13.5 0.0 3 6.9 0.0 2.2 2 0 0 2 2 2 0 Putative sugar-binding domain Abhydrolase_6 PF12697.7 KIY69018.1 - 5.3e-18 66.4 1.7 5.3e-18 66.4 1.7 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KIY69018.1 - 1.4e-05 24.8 0.0 0.00011 22.0 0.0 2.3 2 1 1 3 3 3 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIY69018.1 - 0.002 17.4 0.0 0.012 14.8 0.0 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_8 PF06259.12 KIY69018.1 - 0.0099 15.5 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase Lipase_3 PF01764.25 KIY69018.1 - 0.15 11.9 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_5 PF12695.7 KIY69018.1 - 0.18 11.5 0.0 0.45 10.3 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase family Peptidase_S10 PF00450.22 KIY69018.1 - 0.18 11.1 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 Serine carboxypeptidase MFS_1 PF07690.16 KIY69019.1 - 6.9e-33 114.0 31.0 3.2e-32 111.8 31.4 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily GPI-anchored PF10342.9 KIY69020.1 - 0.00025 21.8 0.0 0.00031 21.4 0.0 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family F-box-like PF12937.7 KIY69021.1 - 2.9e-07 30.3 1.3 1.1e-06 28.4 1.1 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIY69021.1 - 0.0032 17.3 1.4 0.29 11.1 1.4 2.9 2 1 0 2 2 2 1 F-box domain PH PF00169.29 KIY69022.1 - 0.00022 21.7 0.3 0.00087 19.8 0.0 2.2 2 0 0 2 2 2 1 PH domain CDC45 PF02724.14 KIY69023.1 - 5.2 5.2 11.7 3.3 5.9 9.7 1.6 2 0 0 2 2 2 0 CDC45-like protein ABC_tran PF00005.27 KIY69024.1 - 4.2e-47 160.1 0.1 5.2e-23 82.1 0.0 2.9 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 KIY69024.1 - 1.6e-21 76.1 3.4 3.8e-21 74.9 2.5 2.1 2 0 0 2 2 1 1 ABC transporter AAA_21 PF13304.6 KIY69024.1 - 3.2e-15 56.7 8.2 5.5e-05 23.1 0.1 4.2 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KIY69024.1 - 2.2e-09 37.1 0.4 0.15 11.5 0.0 4.3 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KIY69024.1 - 1.1e-08 35.8 0.8 0.0082 16.7 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 KIY69024.1 - 1.6e-08 35.1 0.1 0.00012 22.5 0.1 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 KIY69024.1 - 2.5e-08 33.5 0.5 0.0024 17.6 0.1 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain NACHT PF05729.12 KIY69024.1 - 4.9e-06 26.6 0.1 0.09 12.7 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_15 PF13175.6 KIY69024.1 - 1.2e-05 25.2 8.3 0.32 10.6 0.0 4.4 2 2 2 4 4 4 2 AAA ATPase domain RsgA_GTPase PF03193.16 KIY69024.1 - 3.1e-05 24.0 1.6 0.039 13.9 0.0 3.3 3 0 0 3 3 3 1 RsgA GTPase MMR_HSR1 PF01926.23 KIY69024.1 - 6.9e-05 22.9 0.1 0.18 11.9 0.0 3.0 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA_30 PF13604.6 KIY69024.1 - 0.00019 21.2 0.0 0.024 14.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KIY69024.1 - 0.00023 21.4 0.0 0.76 10.0 0.0 3.0 2 1 1 3 3 2 2 AAA domain AAA_28 PF13521.6 KIY69024.1 - 0.00053 20.3 0.0 0.17 12.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 KIY69024.1 - 0.00078 18.7 0.0 1.1 8.3 0.0 2.6 2 0 0 2 2 2 2 NB-ARC domain RNA_helicase PF00910.22 KIY69024.1 - 0.001 19.4 1.3 3 8.3 0.0 3.3 3 0 0 3 3 3 1 RNA helicase AAA_24 PF13479.6 KIY69024.1 - 0.0011 18.7 0.3 2 8.1 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 KIY69024.1 - 0.0015 19.0 0.1 3.4 8.2 0.0 3.5 3 1 0 3 3 3 1 AAA domain FtsK_SpoIIIE PF01580.18 KIY69024.1 - 0.0018 17.7 0.1 0.7 9.2 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_33 PF13671.6 KIY69024.1 - 0.0021 18.2 0.1 4.4 7.5 0.0 3.2 3 1 0 3 3 3 1 AAA domain AAA_25 PF13481.6 KIY69024.1 - 0.0024 17.5 0.1 9.1 5.8 0.0 3.7 3 0 0 3 3 3 0 AAA domain ATP-synt_ab PF00006.25 KIY69024.1 - 0.0029 17.3 0.5 0.58 9.8 0.0 3.1 3 1 0 4 4 3 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_14 PF13173.6 KIY69024.1 - 0.0047 17.0 0.0 11 6.1 0.0 4.1 5 0 0 5 5 4 0 AAA domain AAA PF00004.29 KIY69024.1 - 0.0052 17.2 0.3 6.2 7.3 0.2 3.8 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.17 KIY69024.1 - 0.0052 16.9 10.0 0.96 9.5 0.5 4.9 4 2 2 6 6 6 2 Helicase HerA, central domain G-alpha PF00503.20 KIY69024.1 - 0.009 15.2 0.3 2.4 7.2 0.0 3.1 2 1 0 2 2 2 1 G-protein alpha subunit NTPase_1 PF03266.15 KIY69024.1 - 0.011 15.7 2.1 1 9.2 0.1 3.4 4 0 0 4 4 3 0 NTPase Roc PF08477.13 KIY69024.1 - 0.011 16.0 0.0 7.7 6.8 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_5 PF07728.14 KIY69024.1 - 0.012 15.6 0.4 7 6.7 0.1 3.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Dynamin_N PF00350.23 KIY69024.1 - 0.013 15.6 8.6 0.65 10.0 0.0 4.2 2 2 1 3 3 3 0 Dynamin family AAA_13 PF13166.6 KIY69024.1 - 0.024 13.3 2.7 0.6 8.7 0.0 3.1 3 1 0 3 3 3 0 AAA domain DUF815 PF05673.13 KIY69024.1 - 0.028 13.6 0.2 6.5 5.8 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 KIY69024.1 - 0.038 13.7 0.0 3 7.5 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_7 PF12775.7 KIY69024.1 - 0.053 13.0 0.0 7.9 5.9 0.0 2.6 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_27 PF13514.6 KIY69024.1 - 0.057 13.0 0.0 12 5.4 0.0 3.0 3 0 0 3 3 2 0 AAA domain DAP3 PF10236.9 KIY69024.1 - 0.074 12.2 2.0 6.7 5.8 0.1 3.0 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 SbcCD_C PF13558.6 KIY69024.1 - 0.093 13.0 0.1 3.1 8.1 0.0 3.0 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit MukB PF04310.12 KIY69024.1 - 0.095 12.5 0.0 3 7.6 0.0 2.9 3 0 0 3 3 3 0 MukB N-terminal ATPase PF06745.13 KIY69024.1 - 0.11 11.9 0.4 11 5.3 0.0 3.1 3 0 0 3 3 3 0 KaiC TsaE PF02367.17 KIY69024.1 - 0.14 12.2 0.3 15 5.6 0.0 3.3 2 1 1 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Pox_A32 PF04665.12 KIY69024.1 - 0.19 11.2 1.5 4.4 6.7 0.0 3.0 3 0 0 3 3 3 0 Poxvirus A32 protein zf-C2H2 PF00096.26 KIY69026.1 - 2.5e-06 27.6 13.3 4.6e-05 23.6 2.2 3.4 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KIY69026.1 - 0.0011 19.3 2.9 0.0011 19.3 2.9 4.7 5 1 0 5 5 5 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KIY69026.1 - 0.045 14.6 1.7 0.045 14.6 1.7 3.8 3 1 1 4 4 4 0 C2H2-type zinc finger FOXP-CC PF16159.5 KIY69026.1 - 0.13 12.9 0.5 0.13 12.9 0.5 2.7 2 1 1 3 3 3 0 FOXP coiled-coil domain zf-met PF12874.7 KIY69026.1 - 1.8 9.1 14.7 1.1 9.7 0.6 3.2 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Ribosomal_S11 PF00411.19 KIY69028.1 - 1.8e-46 157.1 1.3 2.2e-46 156.8 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 CBM_25 PF03423.13 KIY69028.1 - 0.027 14.7 0.0 0.057 13.7 0.0 1.5 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) MAD PF05557.13 KIY69030.1 - 0.017 13.6 36.9 0.12 10.7 21.9 2.0 1 1 1 2 2 2 0 Mitotic checkpoint protein STAG PF08514.11 KIY69030.1 - 0.076 12.9 0.2 0.076 12.9 0.2 2.7 2 1 2 4 4 4 0 STAG domain TPR_MLP1_2 PF07926.12 KIY69030.1 - 0.19 11.8 44.4 1.5 8.9 9.4 3.4 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein DUF745 PF05335.13 KIY69030.1 - 0.4 10.4 35.4 0.33 10.6 15.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Syntaxin-6_N PF09177.11 KIY69030.1 - 0.49 11.0 19.7 0.33 11.5 6.4 2.8 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Spc7 PF08317.11 KIY69030.1 - 0.58 9.0 36.5 1.3 7.9 12.8 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein Filament PF00038.21 KIY69030.1 - 0.65 9.5 37.3 0.3 10.6 12.6 2.1 1 1 1 2 2 2 0 Intermediate filament protein DUF1664 PF07889.12 KIY69030.1 - 0.69 10.0 16.7 1.2 9.1 2.1 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF812 PF05667.11 KIY69030.1 - 1.3 7.8 26.8 1.8 7.3 26.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) GAS PF13851.6 KIY69030.1 - 5 6.4 33.5 0.21 10.9 7.5 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Fez1 PF06818.15 KIY69030.1 - 5.5 7.4 35.8 0.93 9.9 10.1 2.2 1 1 1 2 2 2 0 Fez1 zf-C4H2 PF10146.9 KIY69030.1 - 6.3 7.0 26.8 0.065 13.5 6.5 2.6 1 1 1 2 2 2 0 Zinc finger-containing protein CENP-F_leu_zip PF10473.9 KIY69030.1 - 7.7 6.5 34.8 0.35 10.9 17.8 2.6 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fib_alpha PF08702.10 KIY69030.1 - 8.6 6.5 18.1 4.5 7.5 2.7 2.5 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family THOC7 PF05615.13 KIY69030.1 - 9.1 6.6 39.3 0.093 13.0 11.8 3.0 1 1 1 2 2 1 0 Tho complex subunit 7 Dioxygenase_C PF00775.21 KIY69031.1 - 0.00021 20.8 0.0 0.00044 19.8 0.0 1.6 1 1 0 1 1 1 1 Dioxygenase F-box-like PF12937.7 KIY69032.1 - 0.0009 19.1 0.1 0.002 18.0 0.1 1.6 1 0 0 1 1 1 1 F-box-like AIRC PF00731.20 KIY69033.1 - 1.4e-58 196.6 3.9 3.6e-58 195.4 3.9 1.7 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.22 KIY69033.1 - 1e-53 181.5 0.0 1.5e-53 180.9 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 KIY69033.1 - 5.8e-17 61.1 0.0 1.3e-16 60.0 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 KIY69033.1 - 0.0076 15.8 0.0 0.045 13.3 0.0 1.9 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus CCDC106 PF15794.5 KIY69035.1 - 5.5 6.6 6.4 1.2 8.8 2.9 1.5 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 BTB_2 PF02214.22 KIY69036.1 - 4e-05 23.9 0.0 0.0006 20.1 0.0 2.4 2 0 0 2 2 2 1 BTB/POZ domain AAA PF00004.29 KIY69037.1 - 5.4e-44 149.8 0.0 9.7e-44 149.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KIY69037.1 - 1.5e-11 43.9 0.1 3.1e-11 42.9 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 KIY69037.1 - 1.3e-07 31.9 0.0 2.9e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KIY69037.1 - 2.5e-06 27.5 0.0 9.9e-06 25.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KIY69037.1 - 4.8e-06 27.1 0.1 6.5e-05 23.4 0.0 2.3 1 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KIY69037.1 - 7.2e-06 26.3 0.1 0.0039 17.5 0.1 2.5 1 1 0 1 1 1 1 AAA domain Prot_ATP_ID_OB PF16450.5 KIY69037.1 - 5.6e-05 23.0 0.7 0.00014 21.8 0.7 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain RuvB_N PF05496.12 KIY69037.1 - 9.8e-05 22.2 0.0 0.00022 21.0 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KIY69037.1 - 0.00038 21.0 0.2 0.017 15.7 0.0 2.8 3 0 0 3 3 3 1 AAA domain TIP49 PF06068.13 KIY69037.1 - 0.0013 18.0 0.0 0.0029 16.9 0.0 1.5 1 1 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 KIY69037.1 - 0.0014 18.8 0.0 0.0032 17.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KIY69037.1 - 0.0018 18.1 0.0 0.0049 16.6 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein PhoH PF02562.16 KIY69037.1 - 0.0045 16.5 0.0 0.13 11.7 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein AAA_3 PF07726.11 KIY69037.1 - 0.0076 16.1 0.0 0.016 15.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 KIY69037.1 - 0.0078 15.6 0.1 0.018 14.5 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 KIY69037.1 - 0.0087 16.3 0.0 0.02 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 KIY69037.1 - 0.01 15.2 0.0 0.035 13.5 0.0 1.8 2 0 0 2 2 2 0 KaiC AAA_24 PF13479.6 KIY69037.1 - 0.016 14.9 0.0 0.099 12.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 KIY69037.1 - 0.02 14.6 0.1 0.11 12.2 0.0 2.2 2 1 0 2 2 2 0 Sigma-54 interaction domain TsaE PF02367.17 KIY69037.1 - 0.02 14.9 0.0 0.041 13.9 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 KIY69037.1 - 0.026 13.7 0.0 0.048 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_14 PF13173.6 KIY69037.1 - 0.034 14.2 0.0 0.061 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KIY69037.1 - 0.038 13.5 0.0 0.07 12.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_25 PF13481.6 KIY69037.1 - 0.048 13.2 0.0 0.17 11.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF2072 PF09845.9 KIY69037.1 - 0.048 13.9 0.1 0.097 12.9 0.1 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein RNA_helicase PF00910.22 KIY69037.1 - 0.05 14.0 0.0 0.091 13.2 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Parvo_NS1 PF01057.17 KIY69037.1 - 0.06 12.4 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DivIC PF04977.15 KIY69037.1 - 0.072 12.9 0.2 0.21 11.4 0.2 1.8 1 0 0 1 1 1 0 Septum formation initiator Zeta_toxin PF06414.12 KIY69037.1 - 0.085 12.1 0.0 0.19 11.0 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_13 PF13166.6 KIY69037.1 - 0.091 11.4 0.1 4 6.0 0.1 2.1 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 KIY69037.1 - 0.14 11.9 0.2 0.41 10.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KIY69037.1 - 0.14 12.5 0.0 0.51 10.7 0.0 1.9 2 0 0 2 2 1 0 AAA domain NACHT PF05729.12 KIY69037.1 - 0.16 11.9 0.0 0.64 9.9 0.0 1.9 1 1 1 2 2 2 0 NACHT domain ThrE PF06738.12 KIY69038.1 - 2.4e-50 171.2 26.6 1.3e-48 165.5 11.4 2.2 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 KIY69038.1 - 5.2e-11 42.8 4.6 5.2e-11 42.8 4.6 2.5 2 0 0 2 2 2 2 Threonine/Serine exporter, ThrE NCBP3 PF10309.9 KIY69038.1 - 0.16 11.9 0.0 0.36 10.7 0.0 1.5 1 0 0 1 1 1 0 Nuclear cap-binding protein subunit 3 CGI-121 PF08617.10 KIY69039.1 - 4e-52 176.6 0.4 4.6e-52 176.4 0.4 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Thioredoxin PF00085.20 KIY69040.1 - 3.9e-56 187.4 0.1 1.5e-28 98.8 0.0 3.2 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.6 KIY69040.1 - 3.5e-22 79.2 0.0 6e-11 42.6 0.0 4.0 3 1 1 4 4 4 4 Thioredoxin-like domain OST3_OST6 PF04756.13 KIY69040.1 - 2.4e-12 46.8 0.0 0.00026 20.5 0.0 3.4 3 1 0 3 3 3 3 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 KIY69040.1 - 2.7e-06 27.6 0.0 0.008 16.5 0.0 4.1 3 1 1 4 4 4 1 Thioredoxin-like Thioredoxin_2 PF13098.6 KIY69040.1 - 2.6e-05 24.6 0.2 0.0024 18.3 0.0 2.9 2 1 0 2 2 2 1 Thioredoxin-like domain AhpC-TSA PF00578.21 KIY69040.1 - 0.0015 18.4 0.0 0.012 15.5 0.0 2.4 2 0 0 2 2 2 1 AhpC/TSA family TraF PF13728.6 KIY69040.1 - 0.002 18.0 0.0 0.17 11.7 0.0 2.4 2 0 0 2 2 2 1 F plasmid transfer operon protein Thioredoxin_3 PF13192.6 KIY69040.1 - 0.0088 16.1 0.1 0.34 11.0 0.0 2.6 2 0 0 2 2 2 1 Thioredoxin domain Thioredoxin_7 PF13899.6 KIY69040.1 - 0.1 12.8 0.2 1.1 9.5 0.0 2.6 2 0 0 2 2 2 0 Thioredoxin-like Thioredoxin_4 PF13462.6 KIY69040.1 - 0.12 12.5 1.3 25 5.0 0.2 3.8 3 1 1 4 4 4 0 Thioredoxin 4HBT_3 PF13622.6 KIY69041.1 - 3.9e-14 53.5 0.0 5.8e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily HMG_box PF00505.19 KIY69042.1 - 1.3e-10 41.5 0.1 3.3e-10 40.2 0.1 1.8 1 0 0 1 1 1 1 HMG (high mobility group) box rve_3 PF13683.6 KIY69043.1 - 0.087 12.6 0.2 18 5.2 0.0 3.3 3 0 0 3 3 3 0 Integrase core domain p450 PF00067.22 KIY69044.1 - 1e-58 199.2 0.0 1.2e-58 199.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4131 PF13567.6 KIY69045.1 - 6.5 6.4 7.4 0.83 9.3 2.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Complex1_49kDa PF00346.19 KIY69046.1 - 1.8e-119 397.9 0.0 2.2e-119 397.5 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 KIY69046.1 - 0.01 14.8 0.0 0.016 14.1 0.0 1.3 1 0 0 1 1 1 0 Nickel-dependent hydrogenase UbiA PF01040.18 KIY69047.1 - 6.5e-15 55.1 8.3 9.3e-15 54.6 8.3 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family UbiA PF01040.18 KIY69048.1 - 9.4e-16 57.9 4.2 5e-09 35.8 1.5 2.1 1 1 1 2 2 2 2 UbiA prenyltransferase family Ribosomal_S28e PF01200.18 KIY69050.1 - 5.7e-29 99.9 1.2 7.2e-29 99.6 1.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S28e MS_channel PF00924.18 KIY69051.1 - 1.5e-20 73.6 1.5 4e-20 72.2 1.5 1.7 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 KIY69051.1 - 2.4e-06 26.7 0.2 5.9e-06 25.5 0.2 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KIY69051.1 - 2.1e-05 24.1 0.1 6e-05 22.7 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 KIY69051.1 - 0.00031 21.1 0.0 0.00096 19.6 0.0 1.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 KIY69051.1 - 0.00047 19.5 0.2 0.0015 17.9 0.2 1.9 1 0 0 1 1 1 1 EF hand DUF3098 PF11297.8 KIY69051.1 - 0.23 11.1 3.7 0.17 11.5 1.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3098) adh_short PF00106.25 KIY69052.1 - 1.9e-28 99.2 0.0 3.1e-25 88.8 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KIY69052.1 - 1.3e-17 64.1 0.0 1.1e-16 61.1 0.1 1.9 1 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIY69052.1 - 9.2e-09 35.5 0.1 1.3e-08 34.9 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KIY69052.1 - 3.9e-07 29.8 0.0 5e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KIY69052.1 - 0.00012 21.6 0.0 0.00017 21.1 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Sacchrp_dh_NADP PF03435.18 KIY69052.1 - 0.00022 21.5 0.1 0.00037 20.7 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 KIY69052.1 - 0.025 14.5 0.2 0.048 13.5 0.2 1.4 1 0 0 1 1 1 0 NAD(P)H-binding PALP PF00291.25 KIY69052.1 - 0.042 13.3 0.0 0.067 12.6 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme NAD_binding_4 PF07993.12 KIY69052.1 - 0.054 12.7 0.1 0.081 12.1 0.1 1.4 1 1 0 1 1 1 0 Male sterility protein NmrA PF05368.13 KIY69052.1 - 0.057 13.0 0.1 0.086 12.4 0.1 1.2 1 0 0 1 1 1 0 NmrA-like family 3Beta_HSD PF01073.19 KIY69052.1 - 0.059 12.4 0.0 0.088 11.8 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KIY69052.1 - 0.21 10.7 0.0 0.26 10.4 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Alginate_lyase PF05426.12 KIY69057.1 - 7.9e-15 55.1 1.8 3.6e-13 49.7 2.0 2.1 2 0 0 2 2 2 2 Alginate lyase RA PF00788.23 KIY69058.1 - 3.4e-14 53.2 0.0 2.6e-11 44.0 0.0 3.7 4 0 0 4 4 4 1 Ras association (RalGDS/AF-6) domain SH3_1 PF00018.28 KIY69058.1 - 8.1e-05 22.1 0.0 0.00016 21.2 0.0 1.5 1 0 0 1 1 1 1 SH3 domain Par3_HAL_N_term PF12053.8 KIY69058.1 - 0.0078 16.4 0.1 0.025 14.8 0.1 1.9 1 0 0 1 1 1 1 N-terminal of Par3 and HAL proteins SH3_9 PF14604.6 KIY69058.1 - 0.046 13.6 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 Variant SH3 domain RNA_pol_A_bac PF01000.26 KIY69059.1 - 1.2e-22 80.4 0.0 2.1e-22 79.6 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 KIY69059.1 - 6e-20 70.4 0.0 8.8e-20 69.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Ribosomal_S10 PF00338.22 KIY69060.1 - 3.3e-27 94.6 0.3 4.1e-27 94.3 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Acetyltransf_1 PF00583.25 KIY69062.1 - 4.7e-07 30.1 0.0 7.7e-07 29.4 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KIY69062.1 - 5e-06 26.5 0.0 7e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KIY69062.1 - 7.1e-06 26.4 0.0 3.7e-05 24.1 0.0 1.9 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KIY69062.1 - 0.021 14.9 0.0 0.032 14.3 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 KIY69062.1 - 0.031 14.4 0.1 0.07 13.3 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIY69062.1 - 0.17 11.9 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein Aminotran_3 PF00202.21 KIY69063.1 - 2.2e-41 141.9 0.0 3.1e-21 75.5 0.0 2.5 3 0 0 3 3 3 2 Aminotransferase class-III AAA_26 PF13500.6 KIY69063.1 - 8.6e-17 61.6 0.0 1.7e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain NAT PF04768.13 KIY69064.1 - 2.7e-42 144.3 0.0 4.3e-42 143.7 0.0 1.3 1 0 0 1 1 1 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase AA_kinase PF00696.28 KIY69064.1 - 2e-28 99.6 0.4 6.3e-28 98.0 0.0 1.9 2 0 0 2 2 2 1 Amino acid kinase family Semialdhyde_dh PF01118.24 KIY69064.1 - 7.4e-28 97.4 0.0 2.1e-27 96.0 0.0 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Semialdhyde_dhC PF02774.18 KIY69064.1 - 1.8e-06 28.1 0.0 2.9e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Thiolase_N PF00108.23 KIY69065.1 - 2.1e-64 217.4 0.0 3e-64 216.9 0.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KIY69065.1 - 3e-39 133.4 0.4 6.7e-39 132.3 0.4 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 KIY69065.1 - 0.0021 17.9 0.5 0.17 11.8 0.0 2.8 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 KIY69065.1 - 0.0076 15.9 0.5 0.0076 15.9 0.5 2.3 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain DUF1708 PF08101.11 KIY69066.1 - 3.4e-23 82.5 0.0 3.5e-21 75.9 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF1708) ETF_alpha PF00766.19 KIY69066.1 - 0.079 13.0 0.0 0.21 11.6 0.0 1.7 1 0 0 1 1 1 0 Electron transfer flavoprotein FAD-binding domain PTS-HPr PF00381.19 KIY69066.1 - 0.1 12.9 0.8 0.31 11.3 0.8 1.8 1 0 0 1 1 1 0 PTS HPr component phosphorylation site WGR PF05406.15 KIY69066.1 - 0.17 12.0 0.4 0.37 10.9 0.4 1.5 1 0 0 1 1 1 0 WGR domain DUF2613 PF11021.8 KIY69066.1 - 0.27 11.4 8.3 2.8 8.1 8.3 2.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) Fungal_trans PF04082.18 KIY69067.1 - 2.3e-12 46.5 0.1 4.5e-12 45.6 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY69067.1 - 9.5e-08 32.0 12.9 1.7e-07 31.2 12.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-RING_10 PF16685.5 KIY69067.1 - 1.6 8.9 4.9 3.5 7.8 4.9 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 SNARE_assoc PF09335.11 KIY69068.1 - 2.9e-09 37.4 5.9 2.9e-09 37.4 5.9 2.2 3 0 0 3 3 3 1 SNARE associated Golgi protein SfLAP PF11139.8 KIY69068.1 - 0.013 15.0 0.5 0.06 12.8 0.3 2.0 1 1 1 2 2 2 0 Sap, sulfolipid-1-addressing protein ARID PF01388.21 KIY69069.1 - 4.3e-14 53.0 0.0 1.1e-13 51.6 0.0 1.8 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain FAD_binding_4 PF01565.23 KIY69070.1 - 3.8e-20 72.0 1.4 9.4e-20 70.8 1.4 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KIY69070.1 - 3.3e-10 39.9 0.1 7.2e-10 38.8 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like GRAS PF03514.14 KIY69070.1 - 0.098 11.6 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 GRAS domain family DUF572 PF04502.13 KIY69071.1 - 3.1e-68 230.9 0.0 3.5e-68 230.7 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) Fibrillarin PF01269.17 KIY69072.1 - 2.8e-104 347.2 0.0 3.5e-104 346.9 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 KIY69072.1 - 0.00076 19.2 0.0 0.0012 18.6 0.0 1.3 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 KIY69072.1 - 0.072 12.8 0.1 0.12 12.1 0.1 1.4 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltr_RsmB-F PF01189.17 KIY69072.1 - 0.13 11.9 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 KIY69072.1 - 0.17 12.0 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase DUF4448 PF14610.6 KIY69073.1 - 9.2e-07 28.8 0.0 1.4e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) GPI-anchored PF10342.9 KIY69073.1 - 0.0013 19.5 1.9 0.0019 18.9 0.9 1.9 1 1 1 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family SKG6 PF08693.10 KIY69073.1 - 0.0057 16.0 0.7 0.011 15.2 0.7 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4328 PF14219.6 KIY69073.1 - 0.096 12.2 0.1 0.17 11.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) DUF2207 PF09972.9 KIY69073.1 - 0.16 10.7 0.0 0.21 10.3 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) RTA1 PF04479.13 KIY69074.1 - 1.1e-62 211.4 1.3 1.1e-62 211.4 1.3 1.4 2 0 0 2 2 2 1 RTA1 like protein Terpene_synth_C PF03936.16 KIY69075.1 - 0.034 13.5 0.0 0.055 12.8 0.0 1.3 1 0 0 1 1 1 0 Terpene synthase family, metal binding domain Arch_fla_DE PF04659.13 KIY69075.1 - 0.049 13.5 0.1 0.097 12.5 0.1 1.5 1 0 0 1 1 1 0 Archaeal flagella protein WD40 PF00400.32 KIY69076.1 - 7.6e-17 61.4 6.2 0.029 15.2 0.1 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.8 KIY69076.1 - 0.079 11.6 0.3 0.21 10.2 0.1 1.8 2 0 0 2 2 2 0 Nucleoporin Nup120/160 DSPc PF00782.20 KIY69077.1 - 2.6e-25 88.8 0.0 3.1e-25 88.5 0.0 1.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DUF442 PF04273.13 KIY69077.1 - 8.1e-05 22.7 0.0 0.00014 21.9 0.0 1.3 1 0 0 1 1 1 1 Putative phosphatase (DUF442) Y_phosphatase PF00102.27 KIY69077.1 - 0.0062 16.1 0.0 0.0072 15.9 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 KIY69077.1 - 0.036 14.4 0.0 0.055 13.8 0.0 1.3 1 0 0 1 1 1 0 Rit1 DUSP-like domain TatD_DNase PF01026.21 KIY69077.1 - 0.09 12.1 0.0 0.091 12.1 0.0 1.1 1 0 0 1 1 1 0 TatD related DNase CDKN3 PF05706.12 KIY69077.1 - 0.11 12.2 0.1 0.15 11.8 0.1 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase3 PF13350.6 KIY69077.1 - 0.18 11.8 0.0 0.7 9.8 0.0 1.9 1 1 0 1 1 1 0 Tyrosine phosphatase family Vps51 PF08700.11 KIY69078.1 - 3.8e-22 78.2 0.3 5.4e-22 77.7 0.3 1.2 1 0 0 1 1 1 1 Vps51/Vps67 COG5 PF10392.9 KIY69078.1 - 0.00033 20.8 0.9 0.00048 20.3 0.9 1.1 1 0 0 1 1 1 1 Golgi transport complex subunit 5 Dor1 PF04124.12 KIY69078.1 - 0.00074 18.3 1.3 0.00089 18.0 1.3 1.1 1 0 0 1 1 1 1 Dor1-like family DivIC PF04977.15 KIY69078.1 - 0.18 11.6 0.7 8.8 6.2 0.1 2.1 1 1 1 2 2 2 0 Septum formation initiator DUF4717 PF15838.5 KIY69079.1 - 0.51 10.4 2.6 1.3 9.1 1.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4717) Cyt-b5 PF00173.28 KIY69080.1 - 1.8e-23 82.5 0.1 2.4e-23 82.0 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NDUF_C2 PF06374.11 KIY69082.1 - 0.0017 18.4 0.0 0.0019 18.3 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) TPR_2 PF07719.17 KIY69083.1 - 4.3e-05 23.3 0.1 0.0025 17.8 0.0 3.2 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KIY69083.1 - 0.00038 20.2 0.5 0.0026 17.5 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF4919 PF16266.5 KIY69083.1 - 0.0031 17.5 0.1 0.0056 16.7 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4919) TPR_17 PF13431.6 KIY69083.1 - 0.021 15.2 0.0 0.19 12.2 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 KIY69083.1 - 0.026 15.0 0.0 0.06 13.9 0.0 1.7 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 KIY69083.1 - 0.063 14.1 0.4 0.9 10.5 0.0 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 KIY69083.1 - 0.072 13.3 0.8 0.8 10.1 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4407 PF14362.6 KIY69083.1 - 0.15 11.4 1.2 0.19 11.0 1.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MIF PF01187.18 KIY69084.1 - 2.1e-21 76.3 0.0 2.3e-21 76.2 0.0 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Diphthamide_syn PF01866.17 KIY69086.1 - 4.8e-102 341.5 0.0 5.8e-102 341.2 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Phosphonate-bd PF12974.7 KIY69088.1 - 1e-05 25.3 0.0 2.3e-05 24.1 0.0 1.5 1 1 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1 PF09084.11 KIY69088.1 - 0.00091 19.2 0.0 0.0012 18.8 0.0 1.2 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 KIY69088.1 - 0.011 15.4 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 0 NMT1-like family NMT1_3 PF16868.5 KIY69088.1 - 0.031 13.7 0.0 0.051 13.0 0.0 1.3 1 0 0 1 1 1 0 NMT1-like family RMI1_N PF08585.12 KIY69089.1 - 3.2e-36 125.1 0.0 4.2e-36 124.7 0.0 1.2 1 0 0 1 1 1 1 RecQ mediated genome instability protein Telomerase_RBD PF12009.8 KIY69092.1 - 9.6e-41 139.0 0.4 1.9e-40 138.1 0.4 1.5 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.27 KIY69092.1 - 0.045 13.3 0.0 0.085 12.4 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Glyoxalase_2 PF12681.7 KIY69092.1 - 0.12 12.3 0.1 0.29 11.1 0.1 1.6 1 0 0 1 1 1 0 Glyoxalase-like domain GSHPx PF00255.19 KIY69093.1 - 1.4e-40 137.2 0.2 1.9e-40 136.8 0.2 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 KIY69093.1 - 3.7e-05 23.6 0.1 0.00013 21.9 0.1 1.8 1 1 0 1 1 1 1 AhpC/TSA family DUF5126 PF17166.4 KIY69093.1 - 0.0071 16.2 0.0 0.016 15.1 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF5126) Redoxin PF08534.10 KIY69093.1 - 0.019 14.7 0.0 0.035 13.8 0.0 1.5 1 1 0 1 1 1 0 Redoxin Baculo_LEF-3 PF05847.11 KIY69093.1 - 0.031 13.5 0.0 0.034 13.3 0.0 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus late expression factor 3 (LEF-3) Phosphonate-bd PF12974.7 KIY69093.1 - 0.1 12.2 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein GMC_oxred_N PF00732.19 KIY69094.1 - 3.3e-67 227.0 0.0 4.1e-67 226.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIY69094.1 - 2.1e-35 122.3 0.0 3.5e-35 121.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KIY69094.1 - 8.3e-06 25.1 1.0 1.4e-05 24.3 1.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 KIY69094.1 - 1.6e-05 24.7 1.7 0.00019 21.1 1.7 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KIY69094.1 - 6.2e-05 23.2 0.1 0.00017 21.8 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KIY69094.1 - 0.00028 20.1 1.7 0.00036 19.7 0.7 1.6 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 KIY69094.1 - 0.00029 20.2 0.2 0.00051 19.4 0.2 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 KIY69094.1 - 0.006 15.9 0.4 0.017 14.4 0.2 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KIY69094.1 - 0.0096 14.7 0.4 0.014 14.1 0.4 1.2 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 KIY69094.1 - 0.048 12.7 0.2 0.076 12.1 0.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 KIY69094.1 - 0.11 12.5 0.1 0.28 11.2 0.1 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding Trp_halogenase PF04820.14 KIY69094.1 - 0.53 9.1 2.1 0.29 9.9 0.2 1.5 2 0 0 2 2 2 0 Tryptophan halogenase UDG PF03167.19 KIY69095.1 - 1.9e-15 57.2 0.0 2.9e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily eIF-5_eIF-2B PF01873.17 KIY69096.1 - 1.5e-38 131.3 0.0 2.8e-38 130.4 0.0 1.5 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 KIY69096.1 - 5.2e-23 81.0 2.8 2.5e-22 78.8 0.1 2.7 3 0 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon ACBP PF00887.19 KIY69097.1 - 9.5e-30 102.7 0.3 1.1e-29 102.5 0.3 1.1 1 0 0 1 1 1 1 Acyl CoA binding protein PH PF00169.29 KIY69098.1 - 4.1e-38 130.1 0.1 5.8e-19 68.6 0.1 2.2 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 KIY69098.1 - 3.5e-19 69.2 3.2 2.8e-07 30.9 0.0 3.5 2 1 0 2 2 2 2 Pleckstrin homology domain PH_3 PF14593.6 KIY69098.1 - 8.2e-13 48.4 0.1 2.6e-06 27.5 0.1 3.5 3 1 0 3 3 3 3 PH domain PH_8 PF15409.6 KIY69098.1 - 2.2e-11 43.9 1.7 8.2e-05 22.8 0.2 2.9 3 0 0 3 3 3 2 Pleckstrin homology domain PH_9 PF15410.6 KIY69098.1 - 2.5e-05 24.6 1.0 0.27 11.6 0.6 3.1 2 1 0 2 2 2 2 Pleckstrin homology domain PH_13 PF16652.5 KIY69098.1 - 0.015 15.1 0.1 2.4 7.9 0.0 2.5 2 1 0 2 2 2 0 Pleckstrin homology domain PH_4 PF15404.6 KIY69098.1 - 0.061 13.1 0.1 3.1 7.6 0.0 2.5 2 0 0 2 2 2 0 Pleckstrin homology domain PH_2 PF08458.10 KIY69098.1 - 0.063 13.6 0.0 4.7 7.6 0.0 2.4 2 0 0 2 2 2 0 Plant pleckstrin homology-like region Fungal_trans_2 PF11951.8 KIY69099.1 - 9.3e-22 77.4 0.0 1.1e-21 77.1 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans_2 PF11951.8 KIY69100.1 - 1.6e-44 152.3 0.1 2e-44 151.9 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY69100.1 - 2.8e-05 24.2 7.3 5e-05 23.3 7.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RPA_interact_N PF14766.6 KIY69100.1 - 0.05 13.2 0.2 0.12 12.0 0.2 1.6 1 0 0 1 1 1 0 Replication protein A interacting N-terminal TRAM_LAG1_CLN8 PF03798.16 KIY69101.1 - 4e-32 111.6 18.0 4e-32 111.6 18.0 1.9 2 0 0 2 2 2 1 TLC domain Ndc1_Nup PF09531.10 KIY69101.1 - 6.1 5.4 13.9 1.7 7.2 10.0 1.9 1 1 1 2 2 2 0 Nucleoporin protein Ndc1-Nup EB1 PF03271.17 KIY69102.1 - 3.8e-16 59.0 1.2 3.8e-16 59.0 1.2 1.8 2 0 0 2 2 2 1 EB1-like C-terminal motif CH PF00307.31 KIY69102.1 - 1.5e-06 28.3 0.6 2.5e-06 27.6 0.6 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain Herpes_UL6 PF01763.16 KIY69102.1 - 0.0067 15.0 0.0 0.0095 14.5 0.0 1.2 1 0 0 1 1 1 1 Herpesvirus UL6 like CH_2 PF06294.11 KIY69102.1 - 0.047 13.8 0.3 0.074 13.2 0.3 1.3 1 0 0 1 1 1 0 CH-like domain in sperm protein SUIM_assoc PF16619.5 KIY69102.1 - 0.095 12.8 0.1 0.17 12.0 0.1 1.4 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 MOR2-PAG1_C PF14225.6 KIY69102.1 - 0.15 11.9 0.1 0.26 11.1 0.1 1.3 1 0 0 1 1 1 0 Cell morphogenesis C-terminal FMN_red PF03358.15 KIY69103.1 - 2.2e-09 37.2 0.1 3.3e-09 36.7 0.1 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 KIY69103.1 - 2e-06 27.6 0.1 2.7e-06 27.2 0.1 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 KIY69103.1 - 0.0041 17.3 0.3 0.017 15.3 0.3 2.0 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.7 KIY69103.1 - 0.13 12.4 0.0 1 9.6 0.0 2.0 2 0 0 2 2 2 0 Flavodoxin domain p450 PF00067.22 KIY69104.1 - 6.4e-72 242.8 0.0 7.6e-72 242.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Med26 PF08711.11 KIY69105.1 - 1.9e-08 34.2 0.0 1e-07 31.8 0.0 2.3 2 0 0 2 2 2 1 TFIIS helical bundle-like domain F-box-like PF12937.7 KIY69106.1 - 0.15 12.0 0.5 0.43 10.5 0.3 1.9 2 0 0 2 2 2 0 F-box-like PEX11 PF05648.14 KIY69107.1 - 3.2e-09 36.6 0.2 9.6e-09 35.0 0.2 1.8 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Peptidase_S10 PF00450.22 KIY69108.1 - 5.8e-59 200.6 1.5 2.3e-48 165.6 2.0 2.4 2 1 0 2 2 2 2 Serine carboxypeptidase F_actin_cap_B PF01115.17 KIY69109.1 - 3.7e-106 354.1 0.0 4.3e-106 353.9 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Cupin_1 PF00190.22 KIY69110.1 - 9.7e-39 132.4 0.0 2e-18 66.4 0.0 2.1 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 KIY69110.1 - 1e-28 98.8 0.2 1e-13 50.8 0.1 2.7 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.19 KIY69110.1 - 1.3e-08 34.8 0.1 0.0002 21.3 0.0 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_3 PF05899.12 KIY69110.1 - 1.7e-08 34.0 0.0 0.0027 17.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) MannoseP_isomer PF01050.18 KIY69110.1 - 2.5e-06 27.5 0.0 1.2e-05 25.3 0.0 1.8 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase Cupin_4 PF08007.12 KIY69110.1 - 0.00019 21.0 0.1 0.025 14.0 0.1 2.1 2 0 0 2 2 2 2 Cupin superfamily protein ARD PF03079.14 KIY69110.1 - 0.012 15.8 0.1 0.68 10.1 0.0 2.2 2 0 0 2 2 2 0 ARD/ARD' family 3-HAO PF06052.12 KIY69110.1 - 0.013 15.1 0.0 2.9 7.5 0.0 2.3 2 0 0 2 2 2 0 3-hydroxyanthranilic acid dioxygenase G-alpha PF00503.20 KIY69111.1 - 2.7e-121 405.1 0.0 3.1e-121 404.9 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KIY69111.1 - 3.5e-13 49.4 1.1 2.3e-10 40.2 0.0 2.8 3 0 0 3 3 3 2 ADP-ribosylation factor family Ras PF00071.22 KIY69111.1 - 7.1e-05 22.4 0.1 0.008 15.8 0.0 2.3 2 0 0 2 2 2 1 Ras family Roc PF08477.13 KIY69111.1 - 0.0004 20.6 0.0 1.4 9.1 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 KIY69111.1 - 0.0011 18.4 0.2 0.0042 16.5 0.0 1.9 2 0 0 2 2 2 1 Bacterial TniB protein Gtr1_RagA PF04670.12 KIY69111.1 - 0.0035 16.7 0.2 1.6 8.0 0.0 2.5 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region AAA_24 PF13479.6 KIY69111.1 - 0.004 16.9 0.0 0.13 11.9 0.0 2.3 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KIY69111.1 - 0.033 14.1 0.0 8 6.3 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase AAA_29 PF13555.6 KIY69111.1 - 0.086 12.6 0.0 0.24 11.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATP_bind_1 PF03029.17 KIY69111.1 - 0.095 12.5 0.1 0.85 9.3 0.1 2.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 KIY69111.1 - 0.1 12.1 0.0 1.4 8.4 0.1 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Pro_isomerase PF00160.21 KIY69112.1 - 7.2e-48 162.8 0.0 8.2e-48 162.6 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD VTC PF09359.10 KIY69113.1 - 4.5e-96 321.5 0.8 2e-95 319.3 0.0 2.4 3 0 0 3 3 3 1 VTC domain SPX PF03105.19 KIY69113.1 - 3.5e-12 46.9 38.4 4e-06 27.0 0.6 4.8 2 2 1 4 4 4 3 SPX domain DUF202 PF02656.15 KIY69113.1 - 3.8e-10 40.1 1.6 7.2e-10 39.2 1.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF202) Sigma70_ner PF04546.13 KIY69113.1 - 0.0054 16.6 1.9 0.0054 16.6 1.9 2.5 2 1 0 2 2 2 1 Sigma-70, non-essential region Herpes_UL25 PF01499.16 KIY69113.1 - 0.033 12.7 0.2 0.058 11.9 0.2 1.3 1 0 0 1 1 1 0 Herpesvirus UL25 family Gtr1_RagA PF04670.12 KIY69114.1 - 3.4e-46 157.5 0.0 5.2e-46 156.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 KIY69114.1 - 7.3e-07 28.8 0.0 1.5e-06 27.8 0.0 1.5 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KIY69114.1 - 6.6e-05 23.0 0.0 0.00014 21.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KIY69114.1 - 0.00027 20.4 0.0 0.00046 19.7 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 KIY69114.1 - 0.0011 19.1 0.0 0.002 18.3 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_14 PF13173.6 KIY69114.1 - 0.0021 18.1 0.0 0.0047 16.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain G-alpha PF00503.20 KIY69114.1 - 0.0054 15.9 0.0 0.0078 15.4 0.0 1.3 1 0 0 1 1 1 1 G-protein alpha subunit AAA_16 PF13191.6 KIY69114.1 - 0.0067 16.8 0.0 0.019 15.4 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain PI3K_C2 PF00792.24 KIY69114.1 - 0.016 15.1 0.0 0.056 13.4 0.0 1.7 1 1 1 2 2 2 0 Phosphoinositide 3-kinase C2 TetR_C_15 PF17918.1 KIY69114.1 - 0.018 15.8 0.2 0.055 14.2 0.2 1.9 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Ras PF00071.22 KIY69114.1 - 0.12 12.0 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Ras family DUF815 PF05673.13 KIY69114.1 - 0.14 11.3 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DUF1729 PF08354.10 KIY69115.1 - 2.4e-142 474.0 0.2 8.5e-142 472.2 0.0 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF1729) Acyl_transf_1 PF00698.21 KIY69115.1 - 4.1e-74 249.9 0.1 6.4e-72 242.7 0.0 3.4 4 0 0 4 4 4 1 Acyl transferase domain Fas_alpha_ACP PF18325.1 KIY69115.1 - 7.2e-72 241.0 0.0 1.8e-71 239.7 0.0 1.8 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain FAS_I_H PF18314.1 KIY69115.1 - 6e-68 228.5 0.0 1.4e-67 227.2 0.0 1.7 1 0 0 1 1 1 1 Fatty acid synthase type I helical domain FAS_meander PF17951.1 KIY69115.1 - 1.2e-42 145.1 0.0 2.7e-42 144.0 0.0 1.6 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain SAT PF16073.5 KIY69115.1 - 2e-33 116.1 0.0 3.8e-33 115.2 0.0 1.5 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis MaoC_dehydratas PF01575.19 KIY69115.1 - 2.9e-28 97.9 0.1 2.7e-27 94.8 0.0 2.6 3 0 0 3 3 3 1 MaoC like domain ketoacyl-synt PF00109.26 KIY69115.1 - 3.8e-24 85.7 1.1 7.8e-24 84.6 1.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain FAS_N PF17828.1 KIY69115.1 - 4.7e-23 81.6 0.4 9.1e-23 80.7 0.4 1.5 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta Ketoacyl-synt_C PF02801.22 KIY69115.1 - 8.9e-17 61.2 0.0 2.3e-16 59.9 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ACPS PF01648.20 KIY69115.1 - 4.9e-14 52.4 0.0 1.1e-13 51.3 0.0 1.6 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily MaoC_dehydrat_N PF13452.6 KIY69115.1 - 2.8e-11 43.7 0.5 1.2e-10 41.7 0.0 2.4 3 0 0 3 3 2 1 N-terminal half of MaoC dehydratase adh_short PF00106.25 KIY69115.1 - 6.4e-10 38.8 0.0 6.8e-07 28.9 0.0 2.5 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KIY69115.1 - 1.5e-05 24.7 0.0 0.00021 21.0 0.0 2.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIY69115.1 - 0.0024 17.8 0.1 0.021 14.7 0.0 2.5 2 0 0 2 2 2 1 KR domain Cyclin_N PF00134.23 KIY69116.1 - 1.4e-13 50.7 0.1 9.3e-12 44.8 0.1 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain TFIIB PF00382.19 KIY69116.1 - 0.0043 17.1 0.0 0.043 13.9 0.0 2.5 2 0 0 2 2 2 1 Transcription factor TFIIB repeat Cyclin_C PF02984.19 KIY69116.1 - 0.085 12.9 0.7 1.1 9.4 0.1 2.4 2 0 0 2 2 2 0 Cyclin, C-terminal domain vATP-synt_AC39 PF01992.16 KIY69117.1 - 1.5e-117 392.8 0.1 1.7e-117 392.7 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit TLP1_add_C PF18313.1 KIY69117.1 - 0.063 13.2 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 Thiolase-like protein type 1 additional C-terminal domain CE2_N PF17996.1 KIY69118.1 - 0.1 12.6 0.0 0.42 10.6 0.0 1.9 2 0 0 2 2 2 0 Carbohydrate esterase 2 N-terminal NCBP3 PF10309.9 KIY69119.1 - 8.9e-10 38.3 0.0 1.4e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 FoP_duplication PF13865.6 KIY69119.1 - 4.7e-06 27.1 35.1 0.00024 21.6 12.6 3.3 2 1 2 4 4 4 2 C-terminal duplication domain of Friend of PRMT1 CRAL_TRIO PF00650.20 KIY69120.1 - 5.6e-32 110.7 0.0 8.5e-32 110.1 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KIY69120.1 - 3.4e-05 23.9 0.1 8e-05 22.7 0.1 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain zf-CCHC_3 PF13917.6 KIY69121.1 - 3.1e-15 55.8 1.8 5.9e-15 54.9 1.8 1.5 1 0 0 1 1 1 1 Zinc knuckle Tmemb_cc2 PF10267.9 KIY69121.1 - 0.1 11.7 8.7 0.11 11.6 8.7 1.0 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein CCDC106 PF15794.5 KIY69121.1 - 0.35 10.6 13.0 0.44 10.2 13.0 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 SR-25 PF10500.9 KIY69121.1 - 0.59 9.7 27.8 0.062 12.9 23.9 1.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein eIF3g PF12353.8 KIY69121.1 - 0.68 10.3 6.0 0.14 12.6 1.6 1.9 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G FancD2 PF14631.6 KIY69121.1 - 1.7 6.0 3.5 2 5.7 3.5 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease CDC45 PF02724.14 KIY69121.1 - 2.7 6.2 12.7 3 6.0 12.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Menin PF05053.13 KIY69121.1 - 8 4.7 7.3 8.5 4.6 7.3 1.0 1 0 0 1 1 1 0 Menin Macoilin PF09726.9 KIY69121.1 - 8.1 4.9 12.1 8.7 4.8 12.1 1.1 1 0 0 1 1 1 0 Macoilin family Nucleo_P87 PF07267.11 KIY69121.1 - 8.2 5.2 6.3 9.1 5.0 6.3 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Mannitol_dh_C PF08125.13 KIY69122.1 - 5.2e-50 170.2 0.0 7.6e-50 169.7 0.0 1.3 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 KIY69122.1 - 3.1e-21 76.1 0.0 6.8e-21 75.0 0.0 1.6 1 0 0 1 1 1 1 Mannitol dehydrogenase Rossmann domain UDPG_MGDP_dh_N PF03721.14 KIY69122.1 - 0.027 14.0 0.0 0.042 13.4 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 KIY69122.1 - 0.051 13.5 1.1 0.2 11.5 0.0 2.5 3 1 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Mannitol_dh_C PF08125.13 KIY69123.1 - 1.5e-48 165.5 0.0 3.3e-48 164.3 0.0 1.6 2 0 0 2 2 2 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 KIY69123.1 - 2.7e-20 73.1 0.1 5.7e-20 72.0 0.1 1.6 1 0 0 1 1 1 1 Mannitol dehydrogenase Rossmann domain UDPG_MGDP_dh_N PF03721.14 KIY69123.1 - 0.029 13.9 0.0 0.054 13.1 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 KIY69123.1 - 0.065 13.1 0.1 0.26 11.1 0.0 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain N6-adenineMlase PF10237.9 KIY69124.1 - 2.9e-39 134.4 0.0 3.6e-39 134.2 0.0 1.1 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase T2SSE_N PF05157.15 KIY69124.1 - 0.0078 16.5 0.2 0.037 14.3 0.2 2.0 1 1 1 2 2 2 1 Type II secretion system (T2SS), protein E, N-terminal domain Cons_hypoth95 PF03602.15 KIY69124.1 - 0.034 13.8 0.0 0.052 13.2 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 GNAT_acetyltr_2 PF13718.6 KIY69124.1 - 0.19 11.1 0.0 0.27 10.6 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase 2 DUF2034 PF10356.9 KIY69125.1 - 9.1e-19 67.6 0.9 6.1e-08 32.3 0.1 3.0 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.12 KIY69125.1 - 5.1e-05 23.3 0.0 8.2e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Restriction endonuclease SEN1_N PF12726.7 KIY69126.1 - 1.1e-110 371.2 0.3 1.4e-110 370.7 0.3 1.2 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.6 KIY69126.1 - 1.9e-67 227.8 0.5 1.9e-67 227.8 0.5 2.6 2 1 0 2 2 1 1 AAA domain AAA_12 PF13087.6 KIY69126.1 - 8.2e-57 192.1 0.0 1.6e-56 191.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KIY69126.1 - 1.9e-13 50.6 0.2 8e-09 35.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KIY69126.1 - 3.1e-10 40.6 0.0 2e-09 37.9 0.0 2.3 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KIY69126.1 - 3.8e-05 23.5 0.1 0.034 13.9 0.0 3.5 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 KIY69126.1 - 0.00027 20.9 0.2 0.72 9.7 0.0 2.9 2 0 0 2 2 2 2 Helicase AAA_16 PF13191.6 KIY69126.1 - 0.0029 18.0 0.5 0.019 15.4 0.1 2.8 2 1 0 2 2 1 1 AAA ATPase domain AAA_25 PF13481.6 KIY69126.1 - 0.0051 16.4 0.9 0.016 14.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 KIY69126.1 - 0.012 15.7 0.0 0.052 13.5 0.0 2.1 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA PF00004.29 KIY69126.1 - 0.013 16.0 0.5 0.11 12.9 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) UvrD-helicase PF00580.21 KIY69126.1 - 0.044 13.3 0.0 0.044 13.3 0.0 3.4 2 2 1 3 3 2 0 UvrD/REP helicase N-terminal domain AAA_28 PF13521.6 KIY69126.1 - 0.083 13.1 0.7 5.3 7.3 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KIY69126.1 - 0.22 11.8 3.6 1.2 9.4 0.0 3.7 5 0 0 5 5 5 0 AAA domain Translin PF01997.16 KIY69127.1 - 9.2e-50 169.5 0.0 1.1e-49 169.3 0.0 1.0 1 0 0 1 1 1 1 Translin family SOAR PF16533.5 KIY69127.1 - 0.051 13.5 0.1 0.086 12.8 0.1 1.3 1 0 0 1 1 1 0 STIM1 Orai1-activating region DUF1325 PF07039.11 KIY69128.1 - 1.4e-32 112.5 0.0 2.8e-32 111.5 0.0 1.5 2 0 0 2 2 2 1 SGF29 tudor-like domain Agenet PF05641.12 KIY69128.1 - 0.011 16.2 0.0 0.46 11.0 0.0 2.2 2 0 0 2 2 2 0 Agenet domain Tudor_3 PF18115.1 KIY69128.1 - 0.025 14.4 0.2 0.23 11.3 0.1 2.4 3 0 0 3 3 3 0 DNA repair protein Crb2 Tudor domain CDC45 PF02724.14 KIY69129.1 - 8.8 4.5 12.6 12 4.1 12.6 1.2 1 0 0 1 1 1 0 CDC45-like protein MFS_1 PF07690.16 KIY69130.1 - 2.2e-33 115.7 31.5 2.2e-33 115.7 31.5 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily YpmT PF17431.2 KIY69130.1 - 0.11 12.6 0.4 0.81 9.8 0.2 2.6 2 0 0 2 2 2 0 Uncharacterized YmpT-like OATP PF03137.20 KIY69130.1 - 0.32 9.2 4.7 0.032 12.5 0.2 1.7 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 KIY69131.1 - 1.5e-35 122.8 26.4 1.5e-35 122.8 26.4 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily PCI PF01399.27 KIY69133.1 - 4.7e-20 72.1 0.4 7.5e-19 68.2 0.0 2.7 2 1 0 2 2 2 1 PCI domain RPN5_C PF18098.1 KIY69133.1 - 3.6e-05 23.8 0.3 3.6e-05 23.8 0.3 2.8 3 0 0 3 3 3 1 26S proteasome regulatory subunit RPN5 C-terminal domain YvbH_ext PF11724.8 KIY69133.1 - 0.045 14.1 0.2 1.1 9.7 0.0 2.6 2 0 0 2 2 2 0 YvbH-like oligomerisation region F-box-like PF12937.7 KIY69134.1 - 0.092 12.7 0.4 0.38 10.7 0.1 2.2 2 0 0 2 2 2 0 F-box-like Drc1-Sld2 PF11719.8 KIY69135.1 - 6.6e-16 58.9 16.5 9.7e-16 58.4 16.5 1.3 1 1 0 1 1 1 1 DNA replication and checkpoint protein adh_short PF00106.25 KIY69137.1 - 5.2e-48 163.1 0.0 6.6e-48 162.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIY69137.1 - 3.9e-36 124.8 0.0 4.9e-36 124.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIY69137.1 - 1.3e-07 31.7 0.0 3.4e-07 30.3 0.0 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KIY69137.1 - 3.9e-07 29.8 0.0 1.1e-06 28.3 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 KIY69137.1 - 8e-05 22.1 0.0 0.00025 20.5 0.0 1.9 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) GDP_Man_Dehyd PF16363.5 KIY69137.1 - 0.00011 21.8 0.0 0.00019 21.0 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KIY69137.1 - 0.00028 20.1 0.0 0.00041 19.5 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 KIY69137.1 - 0.00065 19.6 0.0 0.00091 19.2 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding PI-PLC-X PF00388.19 KIY69138.1 - 0.0024 17.5 0.1 0.004 16.8 0.1 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain DUF512 PF04459.12 KIY69138.1 - 0.015 14.5 0.0 0.022 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF512) PI-PLC-C1 PF16670.5 KIY69138.1 - 0.018 14.2 1.3 3.3 6.7 0.0 2.8 2 1 1 3 3 3 0 Phosphoinositide phospholipase C, Ca2+-dependent NMO PF03060.15 KIY69138.1 - 0.18 11.2 0.0 0.46 9.8 0.0 1.6 2 0 0 2 2 2 0 Nitronate monooxygenase HpcH_HpaI PF03328.14 KIY69139.1 - 1e-29 103.3 0.0 1.2e-29 103.0 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family TPR_14 PF13428.6 KIY69140.1 - 1.5e-23 81.5 26.2 0.0035 18.0 0.1 11.8 6 3 7 13 13 13 8 Tetratricopeptide repeat HAT PF02184.16 KIY69140.1 - 1.5e-23 82.4 57.4 7.4e-08 32.2 0.8 14.0 15 1 0 15 15 15 6 HAT (Half-A-TPR) repeat TPR_19 PF14559.6 KIY69140.1 - 1.8e-16 60.4 2.1 0.028 14.9 0.0 8.0 6 1 3 9 9 9 5 Tetratricopeptide repeat TPR_16 PF13432.6 KIY69140.1 - 7.7e-10 39.3 7.0 0.065 13.9 0.0 6.4 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 KIY69140.1 - 1.4e-09 37.3 10.5 0.19 11.9 0.4 7.8 9 0 0 9 9 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 KIY69140.1 - 3.4e-09 36.4 3.2 0.0036 17.6 0.0 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat Suf PF05843.14 KIY69140.1 - 1.1e-07 32.2 18.3 0.22 11.5 1.3 6.2 3 2 2 5 5 5 3 Suppressor of forked protein (Suf) TPR_15 PF13429.6 KIY69140.1 - 2.6e-07 30.1 27.4 0.0049 16.1 1.9 5.5 2 2 3 5 5 5 5 Tetratricopeptide repeat TPR_8 PF13181.6 KIY69140.1 - 2.9e-07 30.2 2.5 0.2 12.0 0.3 7.3 7 0 0 7 7 7 1 Tetratricopeptide repeat SNAP PF14938.6 KIY69140.1 - 4.7e-06 26.2 5.1 0.00088 18.8 0.2 3.5 4 0 0 4 4 4 2 Soluble NSF attachment protein, SNAP TPR_1 PF00515.28 KIY69140.1 - 4e-05 23.2 1.1 0.77 9.7 0.4 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KIY69140.1 - 0.00017 21.6 0.8 1.7 8.8 0.1 4.9 5 0 0 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.6 KIY69140.1 - 0.00058 19.7 5.6 2.4 8.4 0.1 5.7 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 KIY69140.1 - 0.00062 20.0 3.5 0.72 10.2 0.1 6.0 6 1 1 7 7 6 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 KIY69140.1 - 0.00087 19.3 23.3 0.62 10.0 1.7 7.0 5 2 3 8 8 8 2 Mad3/BUB1 homology region 1 TPR_9 PF13371.6 KIY69140.1 - 0.019 15.1 6.3 22 5.3 0.2 5.0 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 KIY69140.1 - 0.033 14.8 12.8 49 4.9 0.1 8.1 8 0 0 8 8 8 0 Tetratricopeptide repeat c-SKI_SMAD_bind PF08782.10 KIY69140.1 - 0.043 14.1 1.9 0.61 10.3 0.2 3.2 3 0 0 3 3 3 0 c-SKI Smad4 binding domain GATase_5 PF13507.6 KIY69141.1 - 1.4e-82 276.7 0.0 2e-82 276.2 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 KIY69141.1 - 7e-37 127.0 0.3 2.2e-26 92.8 0.1 2.3 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 KIY69141.1 - 2.1e-25 88.9 0.0 6.4e-24 84.2 0.0 2.5 1 1 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 KIY69141.1 - 8.9e-21 74.2 0.0 2.1e-20 73.0 0.0 1.7 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain AIRS PF00586.24 KIY69141.1 - 1.4 9.6 7.1 1.1 9.9 1.1 2.8 2 1 0 2 2 2 0 AIR synthase related protein, N-terminal domain Ribonuclease_T2 PF00445.18 KIY69142.1 - 6e-40 137.4 0.3 8.1e-40 137.0 0.3 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family ParA PF10609.9 KIY69143.1 - 5.1e-90 301.2 0.1 6.1e-90 301.0 0.1 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KIY69143.1 - 8.6e-07 29.1 0.0 5.2e-06 26.5 0.0 2.2 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 KIY69143.1 - 6.8e-05 22.9 0.0 0.02 14.8 0.1 2.3 2 0 0 2 2 2 2 AAA domain ArsA_ATPase PF02374.15 KIY69143.1 - 7.5e-05 22.0 0.3 0.0041 16.4 0.1 2.1 2 0 0 2 2 2 1 Anion-transporting ATPase MipZ PF09140.11 KIY69143.1 - 0.00077 18.8 0.0 0.0046 16.3 0.0 2.0 1 1 0 1 1 1 1 ATPase MipZ AAA_25 PF13481.6 KIY69143.1 - 0.0082 15.7 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain Desulfoferrod_N PF06397.12 KIY69143.1 - 0.032 13.9 0.3 0.076 12.6 0.3 1.7 1 0 0 1 1 1 0 Desulfoferrodoxin, N-terminal domain RsgA_GTPase PF03193.16 KIY69143.1 - 0.049 13.5 0.1 0.099 12.5 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_26 PF13500.6 KIY69143.1 - 0.076 12.8 0.3 1.8 8.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KIY69143.1 - 0.13 12.6 0.4 0.17 12.2 0.4 1.4 1 1 0 1 1 1 0 AAA ATPase domain CBP_BcsQ PF06564.12 KIY69143.1 - 0.14 11.6 0.0 0.47 9.9 0.0 1.8 1 1 0 1 1 1 0 Cellulose biosynthesis protein BcsQ NB-ARC PF00931.22 KIY69143.1 - 0.2 10.8 0.1 0.36 10.0 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain DSPc PF00782.20 KIY69146.1 - 2.5e-21 75.9 0.0 3.3e-21 75.5 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain CWC25 PF12542.8 KIY69149.1 - 5.7e-25 88.2 0.4 5.7e-25 88.2 0.4 4.1 3 1 1 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.9 KIY69149.1 - 8.3e-14 51.5 12.4 8.3e-14 51.5 12.4 4.2 3 1 1 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR DUF1754 PF08555.10 KIY69149.1 - 6.3 7.7 25.5 0.11 13.4 9.1 3.1 3 0 0 3 3 3 0 Eukaryotic family of unknown function (DUF1754) Ion_trans PF00520.31 KIY69150.1 - 2e-05 23.9 3.8 2.8e-05 23.5 3.8 1.1 1 0 0 1 1 1 1 Ion transport protein ANTH PF07651.16 KIY69152.1 - 3e-70 236.4 0.0 3e-70 236.4 0.0 3.3 3 1 0 3 3 3 1 ANTH domain I_LWEQ PF01608.17 KIY69152.1 - 2.4e-53 180.5 7.1 2.4e-53 180.5 7.1 6.1 5 1 1 6 6 6 1 I/LWEQ domain ENTH PF01417.20 KIY69152.1 - 0.0022 18.0 0.0 0.019 15.0 0.0 2.8 1 0 0 1 1 1 1 ENTH domain TcdB_N PF12918.7 KIY69152.1 - 0.013 15.8 0.2 0.091 13.1 0.2 2.6 1 0 0 1 1 1 0 TcdB toxin N-terminal helical domain PKcGMP_CC PF16808.5 KIY69152.1 - 0.37 10.7 0.0 0.37 10.7 0.0 4.6 5 0 0 5 5 5 0 Coiled-coil N-terminus of cGMP-dependent protein kinase FAA_hydro_N_2 PF18288.1 KIY69152.1 - 0.62 10.5 6.6 1 9.8 0.8 3.8 2 1 1 3 3 3 0 Fumarylacetoacetase N-terminal domain 2 SURF1 PF02104.15 KIY69153.1 - 1.9e-42 145.5 0.0 2.4e-42 145.1 0.0 1.1 1 0 0 1 1 1 1 SURF1 family Syntaxin-18_N PF10496.9 KIY69154.1 - 0.4 11.0 3.4 1.2 9.5 0.5 2.5 2 0 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus Myb_DNA-bind_7 PF15963.5 KIY69155.1 - 3.6e-22 78.0 0.1 3.6e-22 78.0 0.1 2.1 3 0 0 3 3 3 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 KIY69155.1 - 5.6e-09 36.0 0.0 1.2e-08 35.1 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KIY69155.1 - 0.00013 22.2 0.0 0.00033 20.8 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Beta-lactamase PF00144.24 KIY69156.1 - 2.2e-41 142.2 0.0 3.4e-41 141.6 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.20 KIY69156.1 - 0.054 12.9 0.0 0.12 11.8 0.0 1.5 2 0 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase Beta-lactamase2 PF13354.6 KIY69156.1 - 0.07 12.7 0.0 7.7 6.1 0.0 2.3 2 0 0 2 2 2 0 Beta-lactamase enzyme family Epimerase PF01370.21 KIY69157.1 - 2.1e-13 50.3 0.0 6.7e-13 48.7 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KIY69157.1 - 3.9e-11 42.6 0.0 0.0002 20.5 0.0 2.7 2 2 0 2 2 2 2 RmlD substrate binding domain NAD_binding_10 PF13460.6 KIY69157.1 - 5.1e-11 42.8 0.0 8.1e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KIY69157.1 - 1.7e-10 40.3 0.0 2e-05 23.8 0.0 2.1 1 1 1 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 KIY69157.1 - 3.1e-05 24.2 0.0 6.7e-05 23.1 0.0 1.7 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain adh_short_C2 PF13561.6 KIY69157.1 - 0.00045 19.9 0.0 0.0019 17.8 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase TrkA_N PF02254.18 KIY69157.1 - 0.00048 20.4 0.0 0.0009 19.5 0.0 1.5 1 1 0 1 1 1 1 TrkA-N domain NmrA PF05368.13 KIY69157.1 - 0.00059 19.5 0.1 0.00099 18.7 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 KIY69157.1 - 0.0034 16.9 0.0 0.0049 16.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.12 KIY69157.1 - 0.0037 16.5 0.0 0.01 15.0 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein 2-Hacid_dh_C PF02826.19 KIY69157.1 - 0.01 15.2 0.0 0.044 13.1 0.0 1.9 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain KR PF08659.10 KIY69157.1 - 0.017 15.0 0.0 0.026 14.4 0.0 1.2 1 0 0 1 1 1 0 KR domain ApbA PF02558.16 KIY69157.1 - 0.028 14.1 0.0 0.17 11.5 0.0 2.1 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.23 KIY69157.1 - 0.03 14.3 0.0 0.059 13.3 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.20 KIY69157.1 - 0.041 14.0 0.0 0.065 13.3 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 KIY69157.1 - 0.07 13.7 0.0 0.16 12.5 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DUF3472 PF11958.8 KIY69158.1 - 3.2e-53 180.7 5.6 3.2e-53 180.7 5.6 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3472) DUF5077 PF16871.5 KIY69158.1 - 5.2e-51 173.3 0.6 7.5e-51 172.7 0.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5077) DUF5077 PF16871.5 KIY69159.1 - 2.8e-60 203.5 3.5 4.3e-60 202.9 3.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5077) DUF3472 PF11958.8 KIY69159.1 - 3.7e-55 187.1 4.0 7.3e-55 186.1 4.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3472) CBM-like PF14683.6 KIY69159.1 - 0.00066 19.6 0.8 0.05 13.5 0.3 2.4 2 0 0 2 2 2 2 Polysaccharide lyase family 4, domain III MFS_1 PF07690.16 KIY69160.1 - 5.8e-52 176.8 26.6 2.8e-46 158.1 19.1 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIY69160.1 - 1.8e-13 50.2 9.2 1.8e-13 50.2 9.2 3.2 3 0 0 3 3 3 3 Sugar (and other) transporter MFS_3 PF05977.13 KIY69160.1 - 7.5e-08 31.2 3.9 7.5e-08 31.2 3.9 2.3 3 0 0 3 3 3 1 Transmembrane secretion effector TRI12 PF06609.13 KIY69160.1 - 7.6e-07 27.9 5.2 7.6e-07 27.9 5.2 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 KIY69160.1 - 0.053 12.4 12.9 0.033 13.1 9.2 2.3 2 1 0 2 2 2 0 MFS_1 like family HORMA PF02301.18 KIY69161.1 - 1.4e-07 31.3 0.7 2.2e-07 30.7 0.2 1.7 1 1 0 1 1 1 1 HORMA domain DUF5427 PF10310.9 KIY69161.1 - 3.1 6.7 6.7 4.7 6.1 6.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5427) PX PF00787.24 KIY69162.1 - 5.4e-22 77.9 0.9 3e-21 75.5 0.9 2.0 2 0 0 2 2 2 1 PX domain Vps5 PF09325.10 KIY69162.1 - 5.6e-09 35.9 7.1 0.00055 19.5 0.1 2.4 1 1 0 2 2 2 2 Vps5 C terminal like BAR PF03114.18 KIY69162.1 - 0.00028 20.6 2.1 0.28 10.8 0.4 3.3 3 0 0 3 3 3 1 BAR domain PEP-utilisers_N PF05524.13 KIY69162.1 - 0.039 14.1 1.3 0.12 12.5 0.2 2.3 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal Sec34 PF04136.15 KIY69162.1 - 0.1 12.5 1.2 0.76 9.6 0.0 2.5 2 0 0 2 2 2 0 Sec34-like family GrpE PF01025.19 KIY69162.1 - 0.16 11.6 2.2 1.2 8.8 1.5 2.3 2 0 0 2 2 2 0 GrpE Lung_7-TM_R PF06814.13 KIY69163.1 - 2.6e-65 220.6 17.7 3.2e-65 220.3 17.7 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor TPR_12 PF13424.6 KIY69163.1 - 0.018 15.3 0.1 0.038 14.3 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF202 PF02656.15 KIY69163.1 - 0.7 10.4 0.0 0.7 10.4 0.0 4.0 3 1 0 3 3 3 0 Domain of unknown function (DUF202) RNA_pol_Rpb2_6 PF00562.28 KIY69164.1 - 1.2e-126 422.9 0.3 1.9e-126 422.3 0.3 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KIY69164.1 - 6.9e-67 224.9 0.1 9.9e-67 224.4 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 KIY69164.1 - 3.4e-49 167.1 0.1 6.2e-49 166.2 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 KIY69164.1 - 1.6e-33 115.0 0.3 4.2e-33 113.6 0.1 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.13 KIY69164.1 - 5.7e-26 90.6 1.0 1.1e-25 89.7 0.3 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 KIY69164.1 - 1.5e-25 89.2 0.2 3.5e-25 88.0 0.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 KIY69164.1 - 8.2e-19 67.9 2.5 2e-18 66.7 1.7 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 5 MRNIP PF15749.5 KIY69164.1 - 0.14 12.9 0.6 0.39 11.5 0.6 1.7 1 0 0 1 1 1 0 MRN-interacting protein C1_2 PF03107.16 KIY69164.1 - 0.44 10.9 2.8 2.7 8.4 2.8 2.2 1 1 0 1 1 1 0 C1 domain Fructosamin_kin PF03881.14 KIY69165.1 - 9.1e-64 215.4 0.0 1.1e-63 215.1 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 KIY69165.1 - 2.4e-05 24.4 0.0 0.0001 22.3 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family LMWPc PF01451.21 KIY69166.1 - 0.12 12.8 0.7 0.33 11.3 0.7 1.7 1 0 0 1 1 1 0 Low molecular weight phosphotyrosine protein phosphatase AP_endonuc_2 PF01261.24 KIY69167.1 - 2.3e-32 112.2 0.1 4e-32 111.4 0.1 1.4 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel PBP_sp32 PF07222.12 KIY69167.1 - 0.2 11.1 1.4 0.3 10.5 1.4 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Glyco_transf_8 PF01501.20 KIY69169.1 - 1.4e-20 74.0 0.0 4.1e-20 72.4 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 8 Zip PF02535.22 KIY69169.1 - 0.41 9.8 8.8 0.7 9.1 8.8 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter ABC1 PF03109.16 KIY69170.1 - 1.7e-22 79.8 0.0 1.6e-11 44.4 0.0 2.7 2 0 0 2 2 2 2 ABC1 family APH PF01636.23 KIY69170.1 - 0.14 12.1 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Cohesin_load PF10345.9 KIY69171.1 - 2.7e-08 32.7 0.0 0.011 14.3 0.0 2.8 2 1 0 2 2 2 2 Cohesin loading factor Homeodomain PF00046.29 KIY69172.1 - 1.9e-11 43.6 2.8 1.1e-10 41.2 0.1 2.8 3 0 0 3 3 3 1 Homeodomain Homeobox_KN PF05920.11 KIY69172.1 - 6.2e-06 26.0 0.1 5.5e-05 23.0 0.1 2.3 2 0 0 2 2 2 1 Homeobox KN domain GlutR_dimer PF00745.20 KIY69172.1 - 0.048 14.1 0.5 0.087 13.3 0.5 1.3 1 0 0 1 1 1 0 Glutamyl-tRNAGlu reductase, dimerisation domain TetR_C_32 PF09209.11 KIY69172.1 - 0.13 12.3 0.4 0.22 11.5 0.4 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain FAM199X PF15814.5 KIY69174.1 - 0.28 10.2 3.7 0.56 9.2 3.7 1.4 1 0 0 1 1 1 0 Protein family FAM199X DUF1741 PF08427.10 KIY69176.1 - 1.2e-34 120.0 0.5 1.2e-34 120.0 0.5 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1741) PPR_2 PF13041.6 KIY69177.1 - 1.8e-21 76.1 3.0 5e-05 23.4 0.1 8.3 7 2 1 8 8 8 5 PPR repeat family PPR_3 PF13812.6 KIY69177.1 - 8e-13 48.3 0.8 0.49 10.5 0.0 7.2 6 2 2 8 8 8 5 Pentatricopeptide repeat domain PPR PF01535.20 KIY69177.1 - 1.1e-05 25.3 3.8 0.0049 17.0 0.7 6.2 9 0 0 9 9 9 1 PPR repeat PPR_1 PF12854.7 KIY69177.1 - 0.00025 20.7 0.5 0.74 9.6 0.0 5.1 5 0 0 5 5 5 1 PPR repeat PPR_long PF17177.4 KIY69177.1 - 0.01 15.2 0.2 2.7 7.3 0.1 3.4 3 0 0 3 3 3 0 Pentacotripeptide-repeat region of PRORP SecE PF00584.20 KIY69178.1 - 6.1e-15 54.9 0.0 7e-15 54.7 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex DUF5373 PF17343.2 KIY69179.1 - 0.095 12.5 2.1 0.28 11.0 2.1 1.9 1 1 0 1 1 1 0 Family of unknown function (DUF5373) Vps51 PF08700.11 KIY69180.1 - 5.8e-11 42.3 0.9 2.2e-10 40.5 0.9 2.0 1 0 0 1 1 1 1 Vps51/Vps67 Nop14 PF04147.12 KIY69180.1 - 0.45 8.7 4.8 0.077 11.2 0.6 1.7 2 0 0 2 2 2 0 Nop14-like family MBOAT_2 PF13813.6 KIY69181.1 - 7.7e-16 58.1 4.0 7.7e-16 58.1 4.0 2.2 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family DUF4849 PF16141.5 KIY69181.1 - 0.21 10.8 0.0 0.29 10.4 0.0 1.1 1 0 0 1 1 1 0 Putative glycoside hydrolase Family 18, chitinase_18 DUF1751 PF08551.10 KIY69182.1 - 8.4e-22 77.6 3.4 1.5e-21 76.8 3.4 1.4 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 KIY69182.1 - 0.17 11.9 6.7 0.58 10.2 6.7 1.8 1 1 0 1 1 1 0 Rhomboid family MBOAT_2 PF13813.6 KIY69183.1 - 4e-10 39.8 5.3 8.6e-10 38.8 5.3 1.6 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family RicinB_lectin_2 PF14200.6 KIY69184.1 - 1e-08 35.8 0.1 1.9e-05 25.3 0.0 2.3 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 KIY69184.1 - 0.0079 16.5 0.0 0.12 12.6 0.0 2.1 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain zf-RING_2 PF13639.6 KIY69185.1 - 1.2e-10 41.5 9.7 1.8e-10 41.0 9.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KIY69185.1 - 1.9e-10 40.4 9.8 2.8e-10 39.9 9.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KIY69185.1 - 4e-10 39.4 5.8 5.5e-10 39.0 5.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIY69185.1 - 1.2e-08 34.6 9.9 1.8e-08 34.1 9.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KIY69185.1 - 1.6e-08 34.4 6.4 6.5e-08 32.5 6.7 1.8 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 KIY69185.1 - 4.6e-07 30.0 9.9 1.1e-06 28.8 9.9 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KIY69185.1 - 6.8e-07 29.1 8.4 1e-06 28.6 8.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KIY69185.1 - 0.00071 19.7 11.9 0.0012 19.0 11.9 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KIY69185.1 - 0.0011 18.8 10.3 0.013 15.4 10.5 2.1 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 KIY69185.1 - 0.002 17.8 7.5 0.002 17.8 7.5 1.7 2 0 0 2 2 2 1 RING-like zinc finger zf-ANAPC11 PF12861.7 KIY69185.1 - 0.0055 16.7 5.4 0.013 15.6 5.4 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger UBZ_FAAP20 PF15750.5 KIY69185.1 - 0.22 11.5 4.2 8.2 6.5 0.8 2.5 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger zf-P11 PF03854.14 KIY69185.1 - 0.24 11.1 5.6 1.3 8.7 5.8 1.9 1 1 1 2 2 2 0 P-11 zinc finger zf-RING_4 PF14570.6 KIY69185.1 - 0.35 10.7 8.5 0.94 9.3 8.4 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Rad50_zn_hook PF04423.14 KIY69185.1 - 0.5 10.2 1.7 28 4.7 0.0 2.5 3 0 0 3 3 3 0 Rad50 zinc hook motif DUF1754 PF08555.10 KIY69186.1 - 8.2e-16 58.6 10.2 1.3e-15 58.0 10.2 1.3 1 0 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) Serglycin PF04360.12 KIY69186.1 - 0.00038 20.4 0.3 0.00045 20.2 0.3 1.2 1 0 0 1 1 1 1 Serglycin IATP PF04568.12 KIY69186.1 - 0.085 13.3 6.1 0.091 13.2 4.5 1.8 1 1 1 2 2 2 0 Mitochondrial ATPase inhibitor, IATP WSD PF15613.6 KIY69187.1 - 0.011 16.2 1.7 0.034 14.6 1.7 2.1 1 1 0 1 1 1 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif Glycos_transf_2 PF00535.26 KIY69189.1 - 5.2e-33 114.2 0.0 6.6e-33 113.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KIY69189.1 - 1.5e-13 51.2 0.0 2e-13 50.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 KIY69189.1 - 0.00081 18.9 0.0 0.0011 18.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7N PF13733.6 KIY69189.1 - 0.009 15.6 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_tranf_2_4 PF13704.6 KIY69189.1 - 0.026 15.0 0.1 0.079 13.5 0.1 1.7 1 1 0 1 1 1 0 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KIY69189.1 - 0.18 11.2 0.0 0.3 10.5 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 21 THUMP PF02926.17 KIY69190.1 - 1e-10 41.9 0.7 1.9e-10 41.0 0.7 1.6 1 0 0 1 1 1 1 THUMP domain SMC_N PF02463.19 KIY69191.1 - 2.4e-66 223.3 33.9 9e-66 221.5 33.9 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KIY69191.1 - 9.1e-20 71.1 0.4 5.7e-19 68.5 0.0 2.6 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KIY69191.1 - 1.8e-13 51.0 0.8 4.2e-06 26.8 0.1 3.2 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KIY69191.1 - 5.7e-13 49.3 2.9 5.7e-13 49.3 2.9 4.2 4 2 0 4 4 4 1 AAA ATPase domain AAA_23 PF13476.6 KIY69191.1 - 8.3e-08 33.0 23.4 8.3e-08 33.0 23.4 7.2 3 2 1 4 4 4 1 AAA domain AAA_29 PF13555.6 KIY69191.1 - 4e-05 23.3 0.0 8.6e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain MscS_porin PF12795.7 KIY69191.1 - 0.0018 17.9 47.1 0.0032 17.1 22.9 6.5 4 2 3 7 7 7 2 Mechanosensitive ion channel porin domain KxDL PF10241.9 KIY69191.1 - 0.2 12.0 0.1 0.2 12.0 0.1 7.2 5 2 2 7 7 7 0 Uncharacterized conserved protein ABC_tran PF00005.27 KIY69191.1 - 0.36 11.3 0.0 0.36 11.3 0.0 6.1 6 3 0 6 6 6 0 ABC transporter Clathrin PF00637.20 KIY69192.1 - 9.8e-202 661.0 31.4 1.6e-32 112.3 0.3 7.8 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_propel PF01394.20 KIY69192.1 - 1.7e-36 122.7 0.2 1.1e-07 31.8 0.1 6.8 6 0 0 6 6 6 5 Clathrin propeller repeat Clathrin_H_link PF13838.6 KIY69192.1 - 9.9e-33 111.9 0.1 4.6e-32 109.7 0.1 2.3 1 0 0 1 1 1 1 Clathrin-H-link Clathrin-link PF09268.10 KIY69192.1 - 1.6e-11 43.4 0.1 1.6e-11 43.4 0.1 3.0 3 0 0 3 3 3 1 Clathrin, heavy-chain linker Coatomer_WDAD PF04053.14 KIY69192.1 - 0.0011 18.1 9.6 0.79 8.7 0.1 4.6 5 0 0 5 5 5 2 Coatomer WD associated region TPR_1 PF00515.28 KIY69192.1 - 0.029 14.2 7.8 16 5.5 0.2 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 KIY69192.1 - 0.088 13.7 17.8 41 5.4 0.0 9.7 10 1 1 11 11 9 0 Tetratricopeptide repeat TPR_2 PF07719.17 KIY69192.1 - 0.23 11.6 11.2 43 4.6 0.4 6.6 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_7 PF13176.6 KIY69192.1 - 0.75 10.0 9.4 41 4.5 0.2 6.1 7 0 0 7 7 7 0 Tetratricopeptide repeat DUF1720 PF08226.11 KIY69192.1 - 0.94 9.9 7.7 3.1 8.3 7.7 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1720) TPR_8 PF13181.6 KIY69192.1 - 1.9 8.9 7.3 8.1 6.9 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat Atx10homo_assoc PF09759.9 KIY69193.1 - 2.1e-24 85.4 0.0 4.7e-24 84.3 0.0 1.5 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain SH3_1 PF00018.28 KIY69194.1 - 5e-15 54.8 1.4 3e-06 26.7 0.0 2.8 3 0 0 3 3 3 2 SH3 domain SH3_9 PF14604.6 KIY69194.1 - 5.5e-13 48.6 0.0 5e-05 23.1 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 KIY69194.1 - 7.3e-08 32.0 4.0 3.1e-07 30.0 0.4 2.8 3 0 0 3 3 3 1 Variant SH3 domain RA PF00788.23 KIY69194.1 - 1.3e-07 32.1 0.0 2.6e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SH3_3 PF08239.11 KIY69194.1 - 0.023 15.0 1.8 0.094 13.0 1.9 1.9 2 0 0 2 2 2 0 Bacterial SH3 domain DUF16 PF01519.16 KIY69194.1 - 0.041 14.4 0.0 0.093 13.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function DUF16 SH3_4 PF06347.13 KIY69194.1 - 0.045 13.6 1.0 0.19 11.6 1.0 2.0 1 0 0 1 1 1 0 Bacterial SH3 domain FliD_C PF07195.12 KIY69194.1 - 0.071 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus Leo1 PF04004.13 KIY69195.1 - 8.4e-43 146.1 0.6 1.8e-42 145.0 0.0 1.9 2 0 0 2 2 2 1 Leo1-like protein DUF4245 PF14030.6 KIY69195.1 - 8 6.4 8.0 19 5.2 2.3 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF4245) ArsB PF02040.15 KIY69197.1 - 4.2e-11 42.8 22.4 3.1e-08 33.4 13.7 2.1 2 0 0 2 2 2 2 Arsenical pump membrane protein CitMHS PF03600.16 KIY69197.1 - 5.1e-08 32.5 26.2 5.1e-08 32.5 26.2 2.3 1 1 1 2 2 2 2 Citrate transporter CorA PF01544.18 KIY69198.1 - 3.4e-12 46.3 10.8 1.6e-11 44.0 10.8 1.9 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Suppressor_APC PF11414.8 KIY69198.1 - 0.075 13.1 0.3 0.19 11.8 0.3 1.7 1 0 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein Vma12 PF11712.8 KIY69199.1 - 1.4e-11 44.6 0.0 1.9e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF4231 PF14015.6 KIY69199.1 - 0.0084 16.6 1.5 0.014 15.9 1.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4231) MFS_1 PF07690.16 KIY69199.1 - 0.021 13.8 0.0 0.029 13.3 0.0 1.2 1 0 0 1 1 1 0 Major Facilitator Superfamily Cation_efflux PF01545.21 KIY69199.1 - 0.028 14.1 0.0 0.038 13.7 0.0 1.2 1 0 0 1 1 1 0 Cation efflux family FAM176 PF14851.6 KIY69199.1 - 0.04 13.6 0.1 0.081 12.6 0.0 1.5 2 0 0 2 2 2 0 FAM176 family Transp_cyt_pur PF02133.15 KIY69200.1 - 8.1e-31 107.3 29.7 1.1e-30 106.8 29.7 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF2208 PF09973.9 KIY69202.1 - 0.24 11.0 0.1 0.33 10.6 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) Pkinase PF00069.25 KIY69203.1 - 7.7e-72 241.8 0.0 8.7e-72 241.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY69203.1 - 2.8e-31 108.7 0.0 3.5e-31 108.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KIY69203.1 - 0.0015 17.6 0.1 0.0072 15.3 0.1 1.9 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KIY69203.1 - 0.0044 16.4 0.0 0.013 14.9 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KIY69203.1 - 0.0049 16.8 0.2 0.011 15.7 0.2 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KIY69203.1 - 0.16 11.0 0.0 0.24 10.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Ras PF00071.22 KIY69204.1 - 1.3e-50 171.2 0.0 1.5e-50 171.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIY69204.1 - 8.1e-21 74.5 0.0 1.1e-20 74.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIY69204.1 - 2.8e-06 26.9 0.0 3.5e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KIY69204.1 - 0.0011 18.5 0.0 0.0017 17.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Skp1_POZ PF03931.15 KIY69204.1 - 0.0098 16.1 0.8 0.018 15.2 0.1 1.6 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain MMR_HSR1 PF01926.23 KIY69204.1 - 0.019 15.0 0.0 0.03 14.4 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KIY69204.1 - 0.023 14.0 0.0 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KIY69204.1 - 0.1 12.5 0.0 11 5.9 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 KIY69204.1 - 0.14 12.5 0.0 0.25 11.7 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain NOP19 PF10863.8 KIY69205.1 - 0.071 12.9 0.2 0.11 12.4 0.2 1.2 1 0 0 1 1 1 0 Nucleolar protein 19 RsbU_N PF08673.10 KIY69206.1 - 0.08 13.0 2.4 46 4.2 0.1 3.2 1 1 2 3 3 3 0 Phosphoserine phosphatase RsbU, N-terminal domain SAM_Exu PF18609.1 KIY69206.1 - 0.17 12.0 6.7 0.56 10.3 1.2 2.9 1 1 2 3 3 3 0 Exuperantia SAM-like domain Fib_alpha PF08702.10 KIY69206.1 - 0.61 10.3 5.4 3.1 8.0 2.3 2.3 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family DUF4709 PF15821.5 KIY69206.1 - 2 8.7 11.6 15 5.9 0.4 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4709) Oxidored_FMN PF00724.20 KIY69208.1 - 9.3e-74 248.7 0.0 1.2e-73 248.3 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF346 PF03984.13 KIY69208.1 - 0.0053 16.5 0.1 0.013 15.2 0.1 1.7 1 0 0 1 1 1 1 Repeat of unknown function (DUF346) MEDS PF14417.6 KIY69208.1 - 0.2 11.5 0.0 0.47 10.3 0.0 1.6 1 0 0 1 1 1 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain Mus7 PF09462.10 KIY69211.1 - 3.5e-12 46.0 0.0 4.9e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 Mus7/MMS22 family PAP2_3 PF14378.6 KIY69212.1 - 2.8e-25 89.1 22.6 2.8e-25 89.1 22.6 2.0 1 1 1 2 2 2 1 PAP2 superfamily PAP2 PF01569.21 KIY69212.1 - 8e-09 35.4 8.7 8e-09 35.4 8.7 3.0 3 0 0 3 3 3 1 PAP2 superfamily HSF_DNA-bind PF00447.17 KIY69213.1 - 4.5e-26 91.3 0.1 8.2e-26 90.5 0.1 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding DUF3435 PF11917.8 KIY69213.1 - 0.0076 15.2 2.3 0.011 14.7 1.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3435) Zwint PF15556.6 KIY69213.1 - 0.017 14.6 2.8 0.029 13.9 2.8 1.4 1 0 0 1 1 1 0 ZW10 interactor GCN5L1 PF06320.13 KIY69213.1 - 1.7 8.9 4.6 9.5 6.4 1.0 3.1 4 0 0 4 4 4 0 GCN5-like protein 1 (GCN5L1) Cation_efflux PF01545.21 KIY69214.1 - 2.7e-40 138.2 32.0 2.7e-40 138.2 32.0 3.1 2 1 0 2 2 2 1 Cation efflux family TFIIF_alpha PF05793.12 KIY69214.1 - 9 4.8 10.7 12 4.3 10.7 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Oxidored_FMN PF00724.20 KIY69215.1 - 1.6e-73 247.9 0.0 2e-73 247.6 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF346 PF03984.13 KIY69215.1 - 0.009 15.8 0.1 0.022 14.5 0.1 1.6 1 0 0 1 1 1 1 Repeat of unknown function (DUF346) Acetyltransf_9 PF13527.7 KIY69219.1 - 6.2e-06 26.3 0.0 1.4e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KIY69219.1 - 0.034 14.6 0.0 0.066 13.6 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain alpha-hel2 PF14456.6 KIY69221.1 - 0.31 10.3 1.2 0.51 9.6 1.2 1.2 1 0 0 1 1 1 0 Alpha-helical domain 2 SH3_1 PF00018.28 KIY69222.1 - 6.9e-16 57.6 1.3 7.6e-07 28.7 0.1 2.9 2 1 0 2 2 2 2 SH3 domain SAM_2 PF07647.17 KIY69222.1 - 8.9e-16 57.8 0.0 1.8e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KIY69222.1 - 2.2e-11 44.0 0.0 4.2e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_9 PF14604.6 KIY69222.1 - 2.7e-11 43.2 1.6 8.5e-05 22.3 0.1 2.8 2 0 0 2 2 2 2 Variant SH3 domain RA PF00788.23 KIY69222.1 - 9.9e-07 29.3 0.0 1.9e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SH3_2 PF07653.17 KIY69222.1 - 3.2e-05 23.5 0.4 0.0042 16.7 0.1 2.6 2 0 0 2 2 2 1 Variant SH3 domain SH3_3 PF08239.11 KIY69222.1 - 0.0087 16.3 4.6 0.37 11.1 0.6 2.7 2 0 0 2 2 2 2 Bacterial SH3 domain DnaJ PF00226.31 KIY69223.1 - 1.3e-20 73.3 1.4 1.6e-20 73.0 0.4 1.6 2 0 0 2 2 2 1 DnaJ domain WD40 PF00400.32 KIY69224.1 - 2.9e-13 50.0 5.4 0.051 14.5 0.3 6.8 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY69224.1 - 4.4e-11 42.9 0.2 0.0022 18.3 0.0 4.5 4 0 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_alt PF14077.6 KIY69224.1 - 0.017 15.0 0.1 0.038 13.9 0.1 1.5 1 0 0 1 1 1 0 Alternative WD40 repeat motif Nup160 PF11715.8 KIY69224.1 - 0.044 12.4 0.1 0.21 10.2 0.0 1.9 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Pectate_lyase_3 PF12708.7 KIY69225.1 - 5.5e-94 314.0 20.4 4.4e-83 278.4 10.3 2.7 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 KIY69225.1 - 1.2e-06 28.1 4.0 0.0064 16.2 0.1 2.9 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase DUF1771 PF08590.10 KIY69226.1 - 1.9e-16 60.2 6.8 3.9e-16 59.2 6.8 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) zf_CCCH_4 PF18345.1 KIY69226.1 - 6.4e-08 32.4 8.8 6.1e-06 26.1 1.6 2.8 2 1 0 2 2 2 2 Zinc finger domain zf-CCCH PF00642.24 KIY69226.1 - 5.4e-07 29.4 7.0 3.9e-05 23.5 0.7 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KIY69226.1 - 3.1e-06 27.9 3.8 9e-05 23.1 0.1 2.4 1 1 1 2 2 2 1 Torus domain Smr PF01713.21 KIY69226.1 - 6.1e-05 23.3 0.0 0.00015 22.1 0.0 1.7 1 0 0 1 1 1 1 Smr domain zf-C3H1 PF10650.9 KIY69226.1 - 0.00043 20.0 3.1 0.013 15.3 0.4 2.4 2 0 0 2 2 2 1 Putative zinc-finger domain zf-CCCH_2 PF14608.6 KIY69226.1 - 0.00047 20.5 6.7 0.13 12.8 0.8 2.4 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger LuxE PF04443.12 KIY69226.1 - 0.007 15.4 0.0 0.01 14.9 0.0 1.1 1 0 0 1 1 1 1 Acyl-protein synthetase, LuxE zf-CCCH_3 PF15663.5 KIY69226.1 - 0.24 11.6 5.9 5.7 7.2 0.4 2.3 1 1 1 2 2 2 0 Zinc-finger containing family zf-CCCH_4 PF18044.1 KIY69226.1 - 0.35 10.7 11.9 3 7.7 5.0 3.2 2 1 0 2 2 2 0 CCCH-type zinc finger Cation_efflux PF01545.21 KIY69227.1 - 1.1e-42 146.0 1.3 1.6e-42 145.5 1.3 1.2 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KIY69227.1 - 3.8e-06 26.9 0.0 7.8e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter DUF21 PF01595.20 KIY69228.1 - 0.17 11.6 0.5 0.31 10.7 0.5 1.4 1 0 0 1 1 1 0 Cyclin M transmembrane N-terminal domain CDC45 PF02724.14 KIY69228.1 - 1.4 7.2 12.0 1.6 7.0 12.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.7 KIY69228.1 - 1.8 6.6 4.3 1.9 6.5 4.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Mg_trans_NIPA PF05653.14 KIY69231.1 - 1.9e-92 309.5 13.2 2.3e-92 309.3 13.2 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KIY69231.1 - 0.02 15.1 3.7 0.02 15.1 3.7 2.9 3 0 0 3 3 3 0 EamA-like transporter family Cys_Met_Meta_PP PF01053.20 KIY69232.1 - 4.1e-21 74.9 0.0 5.2e-21 74.6 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KIY69232.1 - 0.0093 15.2 0.0 0.015 14.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Glyco_hydro_47 PF01532.20 KIY69234.1 - 7.4e-151 503.1 1.8 8.4e-151 502.9 1.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF3644 PF12358.8 KIY69234.1 - 0.17 12.4 0.8 0.66 10.5 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3644) TPR_MLP1_2 PF07926.12 KIY69235.1 - 0.0034 17.5 13.6 0.014 15.5 6.3 2.2 2 0 0 2 2 2 2 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 KIY69235.1 - 0.028 13.3 9.4 0.2 10.5 5.1 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein Fib_alpha PF08702.10 KIY69235.1 - 0.035 14.3 7.4 0.079 13.2 3.6 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Wtap PF17098.5 KIY69235.1 - 0.08 12.9 5.5 4.5 7.2 0.1 2.4 2 0 0 2 2 2 0 WTAP/Mum2p family DUF724 PF05266.14 KIY69235.1 - 0.11 12.4 8.0 0.084 12.7 4.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF5339 PF17274.2 KIY69235.1 - 0.19 12.6 2.2 15 6.5 0.0 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5339) DUF4201 PF13870.6 KIY69235.1 - 0.21 11.3 7.4 0.55 9.9 2.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) APG6_N PF17675.1 KIY69235.1 - 0.42 11.1 11.0 2.8 8.5 5.0 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region CENP-H PF05837.12 KIY69235.1 - 0.49 10.8 8.8 12 6.3 0.1 2.5 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Vps5 PF09325.10 KIY69235.1 - 0.53 9.8 7.7 4.6 6.7 0.2 2.2 2 0 0 2 2 2 0 Vps5 C terminal like FH2 PF02181.23 KIY69235.1 - 0.69 9.0 6.0 3.5 6.6 0.1 2.1 2 0 0 2 2 2 0 Formin Homology 2 Domain ATG16 PF08614.11 KIY69235.1 - 0.72 10.0 10.1 2.1 8.5 5.2 2.2 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Fez1 PF06818.15 KIY69235.1 - 0.91 9.9 12.0 8 6.9 12.2 1.9 1 1 1 2 2 2 0 Fez1 T3SSipB PF16535.5 KIY69235.1 - 2 8.9 10.3 0.21 12.1 3.3 2.3 3 0 0 3 3 3 0 Type III cell invasion protein SipB DUF4140 PF13600.6 KIY69235.1 - 2.3 8.7 6.0 3.2 8.2 0.2 2.8 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) COG2 PF06148.11 KIY69235.1 - 3.3 7.8 7.2 11 6.1 2.1 2.3 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Fungal_trans PF04082.18 KIY69236.1 - 7.8e-20 71.0 0.6 1.6e-19 70.0 0.6 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY69236.1 - 2.1e-05 24.5 9.8 4e-05 23.6 9.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GMC_oxred_N PF00732.19 KIY69237.1 - 9.4e-66 222.2 0.0 1.7e-65 221.3 0.0 1.4 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIY69237.1 - 1.9e-31 109.5 0.0 3.1e-31 108.8 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KIY69237.1 - 7e-05 23.0 0.1 0.00022 21.4 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KIY69237.1 - 0.00013 21.3 0.1 0.00022 20.6 0.1 1.3 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 KIY69237.1 - 0.00042 20.0 0.1 0.011 15.3 0.1 2.7 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KIY69237.1 - 0.0054 15.9 0.4 0.045 12.8 0.1 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KIY69237.1 - 0.013 14.8 0.0 0.042 13.1 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KIY69237.1 - 0.048 12.7 0.1 0.07 12.2 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Tissue_fac PF01108.17 KIY69238.1 - 0.027 14.3 0.6 0.037 13.9 0.6 1.3 1 0 0 1 1 1 0 Tissue factor Zn_clus PF00172.18 KIY69239.1 - 3e-22 78.4 59.3 1.2e-08 34.9 12.2 5.9 5 1 0 5 5 5 5 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 KIY69240.1 - 1.4e-06 28.3 7.3 1.4e-06 28.3 7.3 2.9 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain LSM PF01423.22 KIY69242.1 - 2.4e-20 72.0 0.0 2.9e-20 71.7 0.0 1.1 1 0 0 1 1 1 1 LSM domain HEAT_EZ PF13513.6 KIY69243.1 - 2.5e-17 63.0 11.0 1.2e-12 48.0 0.0 7.0 8 2 0 8 8 8 2 HEAT-like repeat HEAT_2 PF13646.6 KIY69243.1 - 5.5e-15 55.5 8.7 0.014 15.8 0.0 6.7 5 2 1 7 7 7 3 HEAT repeats HEAT PF02985.22 KIY69243.1 - 1.7e-14 52.6 8.4 2.7e-05 24.0 0.0 9.0 10 0 0 10 10 9 2 HEAT repeat IBN_N PF03810.19 KIY69243.1 - 4.8e-12 45.6 0.5 2.3e-10 40.2 0.6 3.2 3 0 0 3 3 3 1 Importin-beta N-terminal domain Arm PF00514.23 KIY69243.1 - 1.9e-08 34.1 4.9 0.042 13.9 0.1 6.2 6 1 1 7 7 7 2 Armadillo/beta-catenin-like repeat MMS19_C PF12460.8 KIY69243.1 - 2.2e-07 30.4 2.0 0.052 12.7 0.0 4.1 4 0 0 4 4 4 3 RNAPII transcription regulator C-terminal Cnd1 PF12717.7 KIY69243.1 - 4.1e-05 23.7 1.0 0.073 13.1 0.0 4.0 2 2 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 KIY69243.1 - 0.00049 18.8 3.5 0.22 10.0 0.1 3.1 2 2 0 2 2 2 2 Adaptin N terminal region DUF3385 PF11865.8 KIY69243.1 - 0.0011 18.9 2.6 2.3 8.1 0.2 4.5 4 2 1 5 5 5 3 Domain of unknown function (DUF3385) CLASP_N PF12348.8 KIY69243.1 - 0.0019 17.8 0.8 23 4.4 0.0 4.3 2 2 2 4 4 4 0 CLASP N terminal Dopey_N PF04118.14 KIY69243.1 - 0.021 13.9 1.4 3.1 6.8 0.0 4.0 5 0 0 5 5 5 0 Dopey, N-terminal CTK3 PF12243.8 KIY69243.1 - 0.088 12.8 1.4 59 3.7 0.2 4.0 3 1 1 4 4 4 0 CTD kinase subunit gamma CTK3 WXG100 PF06013.12 KIY69244.1 - 0.11 12.7 0.1 0.35 11.1 0.1 1.8 1 0 0 1 1 1 0 Proteins of 100 residues with WXG zf-MYND PF01753.18 KIY69246.1 - 3.6e-06 27.0 9.3 6e-06 26.2 9.3 1.4 1 0 0 1 1 1 1 MYND finger Pkinase PF00069.25 KIY69247.1 - 4.2e-72 242.7 0.0 5.5e-72 242.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY69247.1 - 1.2e-33 116.6 0.0 1.7e-33 116.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 KIY69247.1 - 2e-11 44.4 0.1 1.1e-09 38.8 0.1 3.0 1 1 0 1 1 1 1 Adenylate sensor of SNF1-like protein kinase UBA_2 PF08587.11 KIY69247.1 - 7.3e-08 32.4 0.0 1.4e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.6 KIY69247.1 - 1.7e-07 30.8 0.0 2.6e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KIY69247.1 - 0.0028 17.0 0.1 0.023 14.0 0.1 2.0 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KIY69247.1 - 0.003 16.5 0.0 0.0045 16.0 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 KIY69247.1 - 0.03 13.9 0.0 0.051 13.2 0.0 1.2 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 KIY69247.1 - 0.11 12.4 0.0 0.47 10.3 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Zn_clus PF00172.18 KIY69249.1 - 0.00025 21.1 19.1 0.00061 19.8 19.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SF-assemblin PF06705.11 KIY69249.1 - 0.084 12.2 0.1 0.16 11.3 0.1 1.4 1 0 0 1 1 1 0 SF-assemblin/beta giardin Zn_clus PF00172.18 KIY69250.1 - 2.2e-06 27.7 11.9 3.4e-06 27.1 11.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BMFP PF04380.13 KIY69250.1 - 0.061 13.8 0.2 0.16 12.5 0.2 1.7 1 0 0 1 1 1 0 Membrane fusogenic activity DUF2076 PF09849.9 KIY69250.1 - 0.19 11.7 0.0 0.29 11.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Glyco_hydro_31 PF01055.26 KIY69252.1 - 3.6e-117 392.3 1.1 4.6e-117 391.9 1.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KIY69252.1 - 4.4e-18 65.4 0.2 2.1e-17 63.2 0.2 2.2 2 0 0 2 2 2 1 Galactose mutarotase-like Amidohydro_3 PF07969.11 KIY69253.1 - 5e-89 299.9 0.2 6.1e-89 299.6 0.2 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 KIY69253.1 - 1.4e-13 50.9 0.0 1.5e-11 44.2 0.0 2.7 2 1 0 2 2 2 2 Amidohydrolase family CTP_transf_like PF01467.26 KIY69254.1 - 2.6e-25 89.3 0.0 3.9e-25 88.7 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase-like Sugar_tr PF00083.24 KIY69255.1 - 1.1e-98 331.0 27.8 1.3e-98 330.9 27.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY69255.1 - 7e-28 97.5 20.8 7e-28 97.5 20.8 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sigma70_r4 PF04545.16 KIY69255.1 - 0.021 14.4 0.5 0.23 11.0 0.1 2.3 2 0 0 2 2 2 0 Sigma-70, region 4 DUF21 PF01595.20 KIY69255.1 - 0.24 11.1 3.7 4.7 6.9 0.1 2.5 2 1 0 2 2 2 0 Cyclin M transmembrane N-terminal domain eIF2_C PF09173.11 KIY69256.1 - 1e-34 118.7 0.5 2.5e-34 117.4 0.5 1.7 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 KIY69256.1 - 1.1e-21 77.3 1.6 2e-20 73.2 1.6 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KIY69256.1 - 3.7e-12 46.5 1.0 6.1e-12 45.8 0.2 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 KIY69256.1 - 0.0012 18.8 1.2 0.0085 16.0 0.2 2.3 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 KIY69256.1 - 0.0053 16.8 0.0 0.012 15.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 KIY69256.1 - 0.017 15.2 1.3 0.028 14.4 0.2 1.9 2 0 0 2 2 2 0 C-terminal region of MMR_HSR1 domain F-box-like PF12937.7 KIY69257.1 - 2.9e-06 27.1 2.6 8.4e-06 25.6 2.6 1.9 1 0 0 1 1 1 1 F-box-like eIF-5a PF01287.20 KIY69258.1 - 6.5e-29 99.8 0.2 9.2e-29 99.4 0.2 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold PCMD PF13201.6 KIY69258.1 - 0.0064 16.3 0.0 0.0083 15.9 0.0 1.2 1 0 0 1 1 1 1 Putative carbohydrate metabolism domain EFP_N PF08207.12 KIY69258.1 - 0.009 16.0 0.1 0.015 15.3 0.1 1.4 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain LIM PF00412.22 KIY69259.1 - 1e-21 76.9 13.1 1.8e-11 44.1 2.5 2.1 2 0 0 2 2 2 2 LIM domain zf_C2HC_14 PF18574.1 KIY69259.1 - 0.25 11.2 0.0 0.25 11.2 0.0 3.1 4 0 0 4 4 4 0 C2HC Zing finger domain GPI-anchored PF10342.9 KIY69260.1 - 6.4e-08 33.3 3.2 8.6e-08 32.8 0.6 2.0 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Sen15 PF09631.10 KIY69261.1 - 5.8e-19 68.2 0.0 8.1e-19 67.8 0.0 1.1 1 0 0 1 1 1 1 Sen15 protein Stealth_CR2 PF11380.8 KIY69262.1 - 2.5e-12 46.9 2.0 2.1e-06 27.8 0.1 3.0 1 1 0 2 2 2 2 Stealth protein CR2, conserved region 2 Stealth_CR1 PF17101.5 KIY69262.1 - 1.1e-07 31.5 0.2 2.3e-07 30.4 0.2 1.5 1 0 0 1 1 1 1 Stealth protein CR1, conserved region 1 Stealth_CR3 PF17102.5 KIY69262.1 - 2.2e-07 30.7 0.3 2.2e-07 30.7 0.3 1.9 2 0 0 2 2 2 1 Stealth protein CR3, conserved region 3 Stealth_CR4 PF17103.5 KIY69262.1 - 2.8e-06 27.1 0.0 6.1e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Stealth protein CR4, conserved region 4 Lactamase_B_2 PF12706.7 KIY69263.1 - 2.1e-14 53.5 1.7 5.6e-07 29.3 0.1 2.8 3 0 0 3 3 3 2 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.6 KIY69263.1 - 1.3e-08 34.4 0.0 2.5e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B PF00753.27 KIY69263.1 - 1.7e-05 24.9 0.4 5.5e-05 23.3 0.4 1.8 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Epimerase PF01370.21 KIY69264.1 - 1.2e-16 60.9 0.0 9.1e-16 58.0 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KIY69264.1 - 9e-07 29.0 0.0 2e-06 27.8 0.0 1.5 2 0 0 2 2 2 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KIY69264.1 - 4.7e-06 25.8 0.0 6.9e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KIY69264.1 - 7.1e-05 22.4 0.0 0.00014 21.4 0.0 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 KIY69264.1 - 0.014 14.9 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase NmrA PF05368.13 KIY69264.1 - 0.047 13.3 1.1 0.048 13.2 0.2 1.5 2 0 0 2 2 2 0 NmrA-like family NAD_binding_4 PF07993.12 KIY69264.1 - 0.21 10.7 0.1 4.5 6.3 0.1 2.1 1 1 1 2 2 2 0 Male sterility protein zf-RanBP PF00641.18 KIY69265.1 - 4.1e-06 26.0 17.2 0.00023 20.4 2.9 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others DAHP_synth_1 PF00793.20 KIY69266.1 - 4.2e-99 330.9 0.0 5.1e-99 330.6 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family PIH1 PF08190.12 KIY69267.1 - 2.1e-19 69.6 0.0 3.2e-19 69.0 0.0 1.2 1 0 0 1 1 1 1 PIH1 N-terminal domain PQQ PF01011.21 KIY69268.1 - 0.068 13.1 0.9 8.5 6.5 0.1 2.5 2 0 0 2 2 2 0 PQQ enzyme repeat EKR PF10371.9 KIY69268.1 - 0.07 12.9 0.1 6.8 6.6 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function CotJA PF11007.8 KIY69268.1 - 0.088 12.7 0.0 55 3.7 0.0 3.1 3 0 0 3 3 3 0 Spore coat associated protein JA (CotJA) MtN3_slv PF03083.16 KIY69268.1 - 0.13 12.3 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 Sugar efflux transporter for intercellular exchange PPI_Ypi1 PF07491.11 KIY69268.1 - 0.72 9.7 3.7 3.9 7.4 0.4 2.3 1 1 1 2 2 2 0 Protein phosphatase inhibitor DUF3328 PF11807.8 KIY69269.1 - 2e-39 135.7 3.3 2.2e-39 135.5 3.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF4224 PF13986.6 KIY69269.1 - 0.13 12.2 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4224) Glyco_hydro_47 PF01532.20 KIY69270.1 - 1.6e-151 505.3 0.0 1.9e-151 505.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 GlcNAc_2-epim PF07221.11 KIY69270.1 - 0.1 11.8 0.0 4.8 6.3 0.0 2.7 3 0 0 3 3 3 0 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) UPF0242 PF06785.11 KIY69271.1 - 0.0052 16.9 1.8 0.0052 16.9 1.8 5.3 2 1 2 4 4 4 1 Uncharacterised protein family (UPF0242) N-terminus CreD PF06123.12 KIY69271.1 - 0.091 11.5 0.3 0.19 10.5 0.3 1.4 1 0 0 1 1 1 0 Inner membrane protein CreD NPV_P10 PF05531.12 KIY69271.1 - 2.1 8.9 8.5 1.1 9.8 0.9 3.9 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein CAP59_mtransfer PF11735.8 KIY69273.1 - 3.1e-69 233.3 0.0 4e-69 233.0 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 VHS PF00790.19 KIY69274.1 - 3.9e-13 49.5 0.0 7.4e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 KIY69274.1 - 9.6e-08 32.2 0.1 2.8e-07 30.7 0.1 1.8 1 0 0 1 1 1 1 GAT domain DUF3638 PF12340.8 KIY69275.1 - 8.1e-81 270.6 0.4 1.7e-80 269.6 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 KIY69275.1 - 3.2e-19 68.0 1.2 1.8e-18 65.6 0.1 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3645) ATP-synt_E PF05680.12 KIY69276.1 - 2.2 8.7 4.9 18 5.7 0.4 2.2 2 0 0 2 2 2 0 ATP synthase E chain Chitin_synth_2 PF03142.15 KIY69277.1 - 5.2e-276 916.3 0.0 6.7e-276 916.0 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 KIY69277.1 - 1.4e-11 44.7 0.3 4.3e-11 43.1 0.3 1.9 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KIY69277.1 - 6.3e-08 32.8 0.0 1.5e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KIY69277.1 - 0.0013 18.3 0.0 0.042 13.3 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 KIY69277.1 - 0.19 11.5 0.0 1.3 8.9 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase family 2 SKN1 PF03935.15 KIY69279.1 - 3.4e-188 626.1 4.0 3.9e-188 625.9 4.0 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) PCNA_N PF00705.18 KIY69280.1 - 2.9e-52 175.7 2.2 2.9e-52 175.7 2.2 2.1 2 1 1 3 3 3 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 KIY69280.1 - 3.1e-40 137.3 0.5 6.6e-20 71.6 0.0 2.8 3 0 0 3 3 3 2 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.13 KIY69280.1 - 0.00019 21.0 0.0 0.00076 19.0 0.0 1.9 2 0 0 2 2 2 1 Rad9 Nop14 PF04147.12 KIY69280.1 - 0.0021 16.4 32.4 0.0027 16.0 32.4 1.1 1 0 0 1 1 1 1 Nop14-like family YL1 PF05764.13 KIY69280.1 - 0.0026 17.9 34.1 0.0048 17.0 34.1 1.5 1 0 0 1 1 1 1 YL1 nuclear protein Rad1 PF02144.16 KIY69280.1 - 0.0035 16.4 12.1 0.15 11.1 12.1 2.9 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Drc1-Sld2 PF11719.8 KIY69280.1 - 0.0053 16.4 17.6 0.0074 15.9 17.6 1.3 1 0 0 1 1 1 1 DNA replication and checkpoint protein Lin-8 PF03353.15 KIY69280.1 - 0.036 13.6 16.7 0.058 13.0 15.5 1.8 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist SDA1 PF05285.12 KIY69280.1 - 0.071 12.5 42.2 0.1 12.0 42.2 1.2 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 KIY69280.1 - 0.27 10.5 37.9 0.4 10.0 37.9 1.2 1 0 0 1 1 1 0 BUD22 SLC12 PF03522.15 KIY69280.1 - 2.8 6.9 12.8 3.7 6.5 12.8 1.2 1 0 0 1 1 1 0 Solute carrier family 12 SAPS PF04499.15 KIY69280.1 - 8.1 5.1 17.4 11 4.6 17.4 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Presenilin PF01080.17 KIY69280.1 - 8.5 5.0 16.3 12 4.5 16.3 1.2 1 0 0 1 1 1 0 Presenilin Hid1 PF12722.7 KIY69280.1 - 10 4.1 14.7 13 3.8 14.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein ubiquitin PF00240.23 KIY69282.1 - 7.8e-20 70.4 0.2 1.4e-19 69.6 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 KIY69282.1 - 2e-10 40.3 0.3 2e-10 40.3 0.3 2.8 3 0 0 3 3 3 1 UBA/TS-N domain DUF2407 PF10302.9 KIY69282.1 - 6.3e-07 29.9 0.0 9.8e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD PF11976.8 KIY69282.1 - 1.6e-06 27.9 0.0 2.6e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 KIY69282.1 - 0.00016 21.6 0.0 0.00028 20.7 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 KIY69282.1 - 0.0034 17.5 0.1 0.0063 16.6 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 KIY69282.1 - 0.02 14.9 0.7 0.49 10.5 0.7 2.2 1 1 0 1 1 1 0 Ubiquitin-like domain Ubiquitin_5 PF18037.1 KIY69282.1 - 0.057 13.8 0.1 0.11 12.9 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain CUE PF02845.16 KIY69282.1 - 0.088 12.5 0.2 0.36 10.6 0.0 2.2 2 0 0 2 2 2 0 CUE domain Ubiquitin_2 PF14560.6 KIY69282.1 - 0.15 12.5 0.2 0.47 10.9 0.2 1.7 1 1 0 1 1 1 0 Ubiquitin-like domain STI1 PF17830.1 KIY69282.1 - 2.7 8.0 15.7 4.5 7.3 6.5 3.0 1 1 1 2 2 2 0 STI1 domain MFS_1 PF07690.16 KIY69283.1 - 8.1e-40 136.8 34.7 8.1e-40 136.8 34.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIY69283.1 - 2.2e-11 43.3 12.1 2.2e-11 43.3 12.1 2.9 1 1 0 3 3 3 1 Sugar (and other) transporter RRM_1 PF00076.22 KIY69284.1 - 8.2e-30 102.4 0.2 4.8e-15 55.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KIY69284.1 - 9.8e-11 41.6 0.0 1.9e-05 24.7 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif OB_RNB PF08206.11 KIY69284.1 - 0.002 17.8 0.0 0.39 10.5 0.0 2.8 2 0 0 2 2 2 1 Ribonuclease B OB domain Nup35_RRM_2 PF14605.6 KIY69284.1 - 0.044 13.8 0.0 10 6.2 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KIY69284.1 - 0.18 11.8 0.0 28 4.8 0.0 2.3 2 0 0 2 2 2 0 RNA binding motif ENTH PF01417.20 KIY69285.1 - 1.4e-50 170.5 0.1 2.8e-50 169.6 0.1 1.5 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 KIY69285.1 - 4.9e-05 22.4 0.0 4.9e-05 22.4 0.0 1.9 2 0 0 2 2 2 1 ANTH domain DUF1846 PF08903.11 KIY69285.1 - 0.37 9.3 3.0 0.6 8.6 3.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1846) Pectinesterase PF01095.19 KIY69286.1 - 1.4e-30 106.1 0.1 6.1e-25 87.6 0.1 2.1 1 1 1 2 2 2 2 Pectinesterase polyprenyl_synt PF00348.17 KIY69288.1 - 1.6e-14 53.6 0.1 2.2e-12 46.6 0.2 2.9 2 1 0 2 2 2 1 Polyprenyl synthetase ELFV_dehydrog PF00208.21 KIY69289.1 - 1.2e-54 185.6 0.0 2e-54 184.9 0.0 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 KIY69289.1 - 1.8e-21 75.5 0.0 3.3e-16 58.1 0.0 2.3 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase PliI PF16743.5 KIY69289.1 - 0.063 13.0 0.1 1.2 8.9 0.0 2.4 2 0 0 2 2 2 0 Periplasmic lysozyme inhibitor of I-type lysozyme NifU PF01106.17 KIY69290.1 - 0.0019 18.3 0.0 1.3 9.2 0.0 2.5 2 0 0 2 2 2 2 NifU-like domain PEP-utilisers_N PF05524.13 KIY69290.1 - 0.057 13.6 0.1 2.4 8.4 0.0 2.4 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal Herpes_capsid PF06112.11 KIY69290.1 - 4.8 7.2 17.0 9.2 6.3 17.0 1.5 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Glyco_hydro_16 PF00722.21 KIY69291.1 - 5.2e-05 22.8 0.1 8.5e-05 22.1 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Glyco_hydro_20 PF00728.22 KIY69292.1 - 1.1e-89 301.4 0.1 1.2e-89 301.1 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 KIY69292.1 - 9.7e-13 49.0 0.0 2e-12 48.0 0.0 1.6 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 KIY69292.1 - 1e-07 32.7 0.0 2.2e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 ENTH PF01417.20 KIY69293.1 - 9.6e-45 151.7 0.2 1.4e-44 151.1 0.2 1.2 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 KIY69293.1 - 0.014 14.4 0.0 0.02 13.9 0.0 1.2 1 0 0 1 1 1 0 ANTH domain VHS PF00790.19 KIY69293.1 - 0.084 12.7 0.1 0.15 11.9 0.1 1.4 1 0 0 1 1 1 0 VHS domain zf-MYND PF01753.18 KIY69294.1 - 4.9e-08 32.9 13.1 9.3e-08 32.0 13.1 1.5 1 0 0 1 1 1 1 MYND finger Ribosomal_L5_C PF00673.21 KIY69295.1 - 8.5e-21 73.9 0.0 1.3e-20 73.3 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 KIY69295.1 - 2e-18 66.5 2.0 2e-18 66.5 0.1 2.0 3 0 0 3 3 3 1 Ribosomal protein L5 Orn_Arg_deC_N PF02784.16 KIY69296.1 - 3.1e-77 259.3 0.0 4.1e-77 258.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 KIY69296.1 - 6.9e-18 64.7 0.0 7.4e-18 64.6 0.0 1.3 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Proteasome PF00227.26 KIY69297.1 - 9.2e-32 110.1 0.0 1.1e-31 109.8 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Glyco_hydro_71 PF03659.14 KIY69298.1 - 7.2e-123 410.1 5.3 8.4e-123 409.9 5.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Cys_Met_Meta_PP PF01053.20 KIY69299.1 - 5.3e-118 393.9 0.3 1.7e-116 388.9 0.3 2.0 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Met_gamma_lyase PF06838.11 KIY69299.1 - 0.00023 19.8 0.0 0.00034 19.2 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase Aminotran_1_2 PF00155.21 KIY69299.1 - 0.02 14.1 0.0 0.033 13.4 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II Cpn10 PF00166.21 KIY69300.1 - 1.6e-26 92.1 0.0 1.9e-26 92.0 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Rax2 PF12768.7 KIY69302.1 - 0.012 15.1 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity RAP1 PF07218.11 KIY69302.1 - 2.3 6.4 5.3 2.9 6.1 5.3 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Phage_CI_C PF16452.5 KIY69303.1 - 0.024 14.9 0.1 1.5 9.2 0.1 3.1 2 1 1 3 3 3 0 Bacteriophage CI repressor C-terminal domain Lin0512_fam PF09585.10 KIY69303.1 - 0.071 13.2 0.4 0.14 12.2 0.4 1.6 1 0 0 1 1 1 0 Conserved hypothetical protein (Lin0512_fam) Ribosomal_L23eN PF03939.13 KIY69304.1 - 9.2e-25 86.6 10.2 9.2e-25 86.6 10.2 1.9 2 0 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 KIY69304.1 - 5e-16 58.8 1.5 5e-16 58.8 1.5 2.4 2 2 0 2 2 2 1 Ribosomal protein L23 SRPRB PF09439.10 KIY69304.1 - 0.02 14.3 0.1 0.026 13.9 0.1 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Metallophos_2 PF12850.7 KIY69307.1 - 9.4e-16 58.4 0.1 1.3e-15 57.9 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 KIY69307.1 - 1.4e-05 25.7 3.5 0.024 15.2 0.3 2.8 2 1 1 3 3 3 2 Calcineurin-like phosphoesterase DUF2793 PF10983.8 KIY69307.1 - 0.1 12.5 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2793) Proteasome PF00227.26 KIY69308.1 - 6.2e-54 182.4 0.1 8.4e-54 182.0 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KIY69308.1 - 1.3e-13 50.3 0.1 2.9e-13 49.2 0.1 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature UvrD_C PF13361.6 KIY69309.1 - 9.2e-10 38.4 0.0 2.2e-08 33.9 0.0 2.7 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 KIY69309.1 - 1.1e-07 32.3 0.0 3.9e-07 30.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 KIY69309.1 - 5.9e-06 26.0 1.8 0.00014 21.5 0.0 2.7 3 0 0 3 3 3 1 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 KIY69309.1 - 1.2e-05 25.6 0.0 0.0032 17.7 0.0 3.5 3 0 0 3 3 3 1 AAA domain UvrD_C_2 PF13538.6 KIY69309.1 - 0.00014 21.6 0.0 0.46 10.3 0.0 2.6 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain AAA_12 PF13087.6 KIY69309.1 - 0.04 13.5 0.0 0.23 11.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KIY69309.1 - 0.073 12.8 0.0 0.39 10.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 KIY69309.1 - 0.15 12.1 1.3 0.49 10.4 0.1 2.3 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit DEAD PF00270.29 KIY69309.1 - 0.17 11.6 0.0 0.38 10.5 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase TPR_2 PF07719.17 KIY69309.1 - 0.39 11.0 1.8 12 6.3 0.3 3.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Het-C PF07217.11 KIY69310.1 - 3.5e-214 712.5 0.0 4.5e-214 712.1 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C His_Phos_2 PF00328.22 KIY69311.1 - 2e-31 109.7 0.0 2.5e-31 109.4 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) His_Phos_1 PF00300.22 KIY69311.1 - 0.0016 18.2 0.0 0.0034 17.1 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF4170 PF13773.6 KIY69311.1 - 0.093 12.9 0.0 0.24 11.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4170) Nipped-B_C PF12830.7 KIY69312.1 - 1.3e-54 185.1 2.1 6.3e-54 182.8 1.8 2.4 2 0 0 2 2 2 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 KIY69312.1 - 5.8e-13 48.9 0.7 5.8e-13 48.9 0.7 2.6 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.22 KIY69312.1 - 0.00084 19.4 1.3 2.4 8.6 0.0 4.7 4 0 0 4 4 4 1 HEAT repeat SIL1 PF16782.5 KIY69312.1 - 0.0014 18.0 1.7 0.044 13.0 0.0 3.3 4 0 0 4 4 4 1 Nucleotide exchange factor SIL1 Adaptin_N PF01602.20 KIY69312.1 - 0.036 12.6 0.1 0.036 12.6 0.1 2.7 3 0 0 3 3 3 0 Adaptin N terminal region M11L PF11099.8 KIY69312.1 - 0.047 14.0 3.3 1.4 9.2 0.1 2.9 3 0 0 3 3 3 0 Apoptosis regulator M11L like TAN PF11640.8 KIY69312.1 - 0.26 11.4 4.3 30 4.7 0.0 4.3 5 0 0 5 5 5 0 Telomere-length maintenance and DNA damage repair ETF PF01012.21 KIY69313.1 - 1.3e-44 152.3 0.4 1.6e-44 151.9 0.4 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Thioredoxin PF00085.20 KIY69314.1 - 9.7e-24 83.3 0.0 1e-23 83.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 KIY69314.1 - 1.9e-07 31.2 0.2 4e-07 30.1 0.2 1.6 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.6 KIY69314.1 - 1.6e-05 25.1 0.0 0.0024 18.2 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 KIY69314.1 - 3.2e-05 24.3 0.2 9.4e-05 22.8 0.2 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 KIY69314.1 - 4.3e-05 23.0 0.0 4.5e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 KIY69314.1 - 5.2e-05 23.2 0.1 0.00079 19.3 0.0 1.9 1 1 1 2 2 2 1 AhpC/TSA family Thioredoxin_9 PF14595.6 KIY69314.1 - 0.0038 17.0 0.0 0.0044 16.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.10 KIY69314.1 - 0.0044 16.7 0.3 0.039 13.7 0.1 1.9 1 1 1 2 2 2 1 Redoxin TraF PF13728.6 KIY69314.1 - 0.0064 16.3 0.0 0.0074 16.1 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein Phosducin PF02114.16 KIY69314.1 - 0.033 13.1 0.0 0.036 13.0 0.0 1.0 1 0 0 1 1 1 0 Phosducin dCMP_cyt_deam_1 PF00383.23 KIY69315.1 - 2.6e-24 85.0 0.1 3.6e-24 84.6 0.1 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KIY69315.1 - 3.1e-22 78.8 0.0 4.2e-22 78.4 0.0 1.3 1 0 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 KIY69315.1 - 0.00069 19.7 1.6 0.026 14.6 1.6 2.1 1 1 0 1 1 1 1 Bd3614-like deaminase SNAD4 PF18750.1 KIY69315.1 - 0.0018 18.3 0.0 0.0028 17.7 0.0 1.2 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC2 PF18772.1 KIY69315.1 - 0.01 15.9 0.0 0.014 15.4 0.0 1.1 1 0 0 1 1 1 0 APOBEC2 NAD1 PF18778.1 KIY69315.1 - 0.011 15.8 0.0 0.016 15.3 0.0 1.2 1 0 0 1 1 1 0 Novel AID APOBEC clade 1 APOBEC3 PF18771.1 KIY69315.1 - 0.014 15.5 0.0 0.025 14.7 0.0 1.4 1 0 0 1 1 1 0 APOBEC3 APOBEC1 PF18769.1 KIY69315.1 - 0.024 14.9 0.0 0.038 14.3 0.0 1.2 1 0 0 1 1 1 0 APOBEC1 APOBEC4_like PF18774.1 KIY69315.1 - 0.027 14.4 0.0 0.041 13.8 0.0 1.2 1 0 0 1 1 1 0 APOBEC4-like -AID/APOBEC-deaminase APOBEC_N PF08210.11 KIY69315.1 - 0.055 13.4 0.0 0.074 12.9 0.0 1.2 1 0 0 1 1 1 0 APOBEC-like N-terminal domain Pkinase PF00069.25 KIY69316.1 - 2e-72 243.8 0.0 3.7e-72 242.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY69316.1 - 1e-49 169.2 0.0 2.2e-49 168.1 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY69316.1 - 0.0034 16.7 0.0 0.1 11.9 0.0 2.4 2 0 0 2 2 2 1 Kinase-like RICTOR_N PF14664.6 KIY69316.1 - 0.017 14.1 9.6 0.049 12.6 0.3 2.7 1 1 1 2 2 2 0 Rapamycin-insensitive companion of mTOR, N-term Pkinase_fungal PF17667.1 KIY69316.1 - 0.018 13.8 0.0 0.031 13.0 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase DUF4704 PF15787.5 KIY69316.1 - 0.04 13.2 5.2 8.2 5.6 0.2 3.8 3 1 1 4 4 4 0 Domain of unknown function (DUF4704) RTA1 PF04479.13 KIY69317.1 - 7e-63 212.0 4.4 8.8e-63 211.6 4.4 1.1 1 0 0 1 1 1 1 RTA1 like protein DNA_pol_A_exo1 PF01612.20 KIY69320.1 - 5.1e-48 163.1 0.5 7.9e-48 162.5 0.5 1.3 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.12 KIY69320.1 - 6.1e-22 78.1 2.9 8.9e-22 77.6 1.2 2.3 3 0 0 3 3 3 1 PMC2NT (NUC016) domain HRDC PF00570.23 KIY69320.1 - 1.6e-12 47.2 0.0 3.7e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 HRDC domain MFS_1 PF07690.16 KIY69321.1 - 1.4e-50 172.2 20.9 3.2e-50 171.0 19.8 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIY69321.1 - 9.3e-14 51.1 19.1 1.5e-11 43.9 0.6 3.2 3 0 0 3 3 3 3 Sugar (and other) transporter OATP PF03137.20 KIY69321.1 - 0.0012 17.2 6.8 0.002 16.5 0.2 2.8 2 1 1 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family Fe-S_biosyn PF01521.20 KIY69322.1 - 1.8e-21 76.4 0.0 2.4e-21 76.0 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis MIP PF00230.20 KIY69323.1 - 3.3e-26 92.4 9.5 9e-26 91.0 9.5 1.5 1 1 0 1 1 1 1 Major intrinsic protein Peptidase_M64 PF09471.10 KIY69326.1 - 1.2e-30 107.0 0.0 2e-30 106.2 0.0 1.3 1 1 0 1 1 1 1 IgA Peptidase M64 SusF_SusE PF16411.5 KIY69326.1 - 0.016 15.8 0.0 0.16 12.5 0.0 2.6 2 1 2 4 4 4 0 Outer membrane protein SusF_SusE Ig_2 PF13895.6 KIY69326.1 - 0.077 13.3 0.0 0.31 11.4 0.0 2.0 2 0 0 2 2 2 0 Immunoglobulin domain Nas2_N PF18265.1 KIY69327.1 - 1.6e-25 88.8 0.0 2.2e-25 88.4 0.0 1.2 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_6 PF17820.1 KIY69327.1 - 3.5e-08 33.2 0.2 1.6e-07 31.1 0.1 2.0 2 0 0 2 2 2 1 PDZ domain GRASP55_65 PF04495.14 KIY69327.1 - 1.8e-06 28.3 0.0 2.5e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ_2 PF13180.6 KIY69327.1 - 8.4e-05 22.8 0.0 0.0002 21.6 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KIY69327.1 - 0.011 16.1 0.1 0.028 14.8 0.0 1.8 2 1 0 2 2 2 0 PDZ domain Orthopox_A49R PF06489.11 KIY69327.1 - 0.16 12.2 0.1 0.25 11.6 0.1 1.2 1 0 0 1 1 1 0 Orthopoxvirus A49R protein 4HBT PF03061.22 KIY69328.1 - 4e-09 36.7 0.2 6.7e-09 36.0 0.2 1.3 1 0 0 1 1 1 1 Thioesterase superfamily F-box-like PF12937.7 KIY69329.1 - 0.024 14.5 0.1 0.087 12.7 0.1 2.0 1 0 0 1 1 1 0 F-box-like Ribosomal_L5_C PF00673.21 KIY69330.1 - 1.3e-25 89.4 0.0 1.9e-25 88.8 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 KIY69330.1 - 0.035 14.4 0.2 0.076 13.4 0.2 1.5 1 0 0 1 1 1 0 Ribosomal protein L5 FIST PF08495.10 KIY69331.1 - 3.5e-06 27.2 0.0 6.4e-06 26.3 0.0 1.6 1 1 0 1 1 1 1 FIST N domain Aldo_ket_red PF00248.21 KIY69332.1 - 6.2e-49 166.8 0.0 7.2e-48 163.3 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family HTH_23 PF13384.6 KIY69332.1 - 0.008 15.9 0.1 10 6.1 0.0 3.5 3 0 0 3 3 3 2 Homeodomain-like domain Homeodomain PF00046.29 KIY69332.1 - 0.41 10.5 2.8 7.6 6.5 0.0 2.6 3 0 0 3 3 3 0 Homeodomain zf-C2H2_4 PF13894.6 KIY69333.1 - 6.1e-06 26.6 9.4 0.00031 21.3 1.2 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KIY69333.1 - 1.6e-05 25.1 9.2 0.0047 17.3 2.9 3.1 2 1 0 2 2 2 2 Zinc finger, C2H2 type zf-BED PF02892.15 KIY69333.1 - 0.0032 17.5 5.5 0.2 11.7 0.4 3.1 3 0 0 3 3 3 2 BED zinc finger zf-met2 PF12907.7 KIY69333.1 - 0.094 12.9 0.5 0.21 11.7 0.5 1.6 1 0 0 1 1 1 0 Zinc-binding zf-CCHC_2 PF13696.6 KIY69333.1 - 0.22 11.4 4.0 0.39 10.6 0.7 2.6 2 0 0 2 2 2 0 Zinc knuckle zf-H2C2_2 PF13465.6 KIY69333.1 - 0.54 10.8 6.3 7.6 7.2 0.3 3.1 3 0 0 3 3 3 0 Zinc-finger double domain Ribonucleas_3_3 PF14622.6 KIY69334.1 - 3e-16 59.7 0.0 8.2e-16 58.3 0.0 1.7 1 1 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 KIY69334.1 - 0.0047 17.5 0.0 0.0098 16.5 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease III domain Ribosomal_60s PF00428.19 KIY69334.1 - 6.7 7.4 7.2 1.1 9.9 3.2 1.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein FA_desaturase PF00487.24 KIY69335.1 - 7.9e-16 58.6 22.4 1.3e-15 57.9 22.4 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 KIY69335.1 - 1e-12 48.0 0.0 2.2e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain G-alpha PF00503.20 KIY69336.1 - 2.3e-99 332.9 0.0 2.8e-99 332.6 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KIY69336.1 - 2e-10 40.4 3.2 3.1e-07 30.0 0.4 2.7 2 2 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KIY69336.1 - 0.017 14.5 2.9 0.69 9.2 0.1 2.8 2 1 1 3 3 3 0 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KIY69336.1 - 0.032 14.3 0.0 3.3 7.8 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase Roc PF08477.13 KIY69336.1 - 0.11 12.7 0.2 5.7 7.2 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 KIY69336.1 - 0.16 11.8 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain adh_short PF00106.25 KIY69337.1 - 3.3e-18 65.9 0.0 5.3e-18 65.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIY69337.1 - 2e-17 63.5 0.0 2.7e-17 63.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase YjeF_N PF03853.15 KIY69337.1 - 0.074 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 YjeF-related protein N-terminus 3HCDH_N PF02737.18 KIY69337.1 - 0.09 12.6 0.2 0.15 12.0 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Peptidase_M16 PF00675.20 KIY69338.1 - 8.5e-53 178.3 0.1 2.3e-52 176.9 0.1 1.7 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KIY69338.1 - 4.1e-40 137.8 0.0 6.9e-38 130.5 0.0 2.7 3 0 0 3 3 3 2 Peptidase M16 inactive domain DUF563 PF04577.14 KIY69339.1 - 1.3e-19 71.2 0.1 3.2e-19 69.9 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF563) TfoX_N PF04993.13 KIY69339.1 - 0.0088 16.2 0.0 2.5 8.4 0.0 2.9 3 0 0 3 3 3 2 TfoX N-terminal domain DUF1372 PF07116.11 KIY69340.1 - 0.14 12.4 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1372) RNase_H PF00075.24 KIY69342.1 - 4.4e-13 49.6 0.0 1.2e-12 48.2 0.0 1.7 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.6 KIY69342.1 - 4.7e-06 27.2 0.5 1.9e-05 25.3 0.5 2.1 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase RVT_1 PF00078.27 KIY69343.1 - 1.8e-06 27.7 0.0 3.5e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Syntaxin_2 PF14523.6 KIY69344.1 - 1.4e-22 80.0 7.7 2.8e-21 75.7 4.2 2.3 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.19 KIY69344.1 - 5.8e-12 45.4 0.6 5.8e-12 45.4 0.6 1.9 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 KIY69344.1 - 8e-08 32.2 8.7 2.7e-07 30.5 8.7 1.8 1 1 0 1 1 1 1 Syntaxin MCPsignal PF00015.21 KIY69344.1 - 0.026 14.3 1.8 0.064 13.1 0.2 2.1 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF16 PF01519.16 KIY69344.1 - 0.19 12.2 4.9 0.16 12.5 0.4 2.4 2 1 0 2 2 2 0 Protein of unknown function DUF16 DUF2730 PF10805.8 KIY69344.1 - 0.2 11.8 2.1 0.92 9.6 0.4 2.6 2 2 0 2 2 2 0 Protein of unknown function (DUF2730) Prominin PF05478.11 KIY69344.1 - 0.23 9.4 4.6 0.14 10.1 0.2 1.8 1 1 0 2 2 2 0 Prominin DUF3708 PF12501.8 KIY69344.1 - 0.35 10.7 5.8 0.14 12.0 0.6 2.2 2 1 0 2 2 2 0 Phosphate ATP-binding cassette transporter Synaptobrevin PF00957.21 KIY69344.1 - 8.5 6.3 6.8 7.4 6.4 1.8 2.8 2 1 0 2 2 2 0 Synaptobrevin Peptidase_M16 PF00675.20 KIY69346.1 - 6.6e-20 71.6 0.0 1e-19 71.0 0.0 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) DNA_ligase_A_C PF04679.15 KIY69346.1 - 0.13 12.8 0.0 2.2 9.0 0.0 2.5 1 1 1 2 2 2 0 ATP dependent DNA ligase C terminal region MRP-L28 PF09812.9 KIY69347.1 - 4.7e-11 43.1 3.4 7.7e-10 39.1 1.6 2.2 1 1 1 2 2 2 1 Mitochondrial ribosomal protein L28 Lant_dehydr_C PF14028.6 KIY69347.1 - 0.023 14.3 1.1 0.029 13.9 1.1 1.1 1 0 0 1 1 1 0 Lantibiotic biosynthesis dehydratase C-term DUF4375 PF14300.6 KIY69347.1 - 0.041 14.2 0.1 0.072 13.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4375) Glyco_hydro_9 PF00759.19 KIY69347.1 - 0.079 12.4 0.0 0.084 12.3 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 9 PCI PF01399.27 KIY69348.1 - 1.4e-18 67.3 0.4 3.8e-18 65.9 0.4 1.8 1 0 0 1 1 1 1 PCI domain DUF5517 PF17639.2 KIY69348.1 - 0.2 12.0 7.4 0.17 12.2 0.8 3.3 3 1 0 3 3 3 0 Family of unknown function (DUF5517) YL1 PF05764.13 KIY69348.1 - 1 9.4 4.0 1.9 8.6 4.0 1.4 1 0 0 1 1 1 0 YL1 nuclear protein Granulin PF00396.18 KIY69349.1 - 0.084 13.2 28.3 1.2 9.5 5.5 3.4 1 1 2 3 3 3 0 Granulin PIP5K PF01504.18 KIY69350.1 - 9.7e-47 159.5 0.5 4.4e-38 131.1 0.4 2.4 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 KIY69350.1 - 4.4e-22 78.4 0.0 7.3e-22 77.6 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 KIY69350.1 - 7.9e-17 61.2 13.6 1.8e-16 60.0 13.6 1.7 1 0 0 1 1 1 1 FYVE zinc finger IBR PF01485.21 KIY69350.1 - 0.14 12.4 11.9 0.068 13.4 7.2 2.4 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain Bromodomain PF00439.25 KIY69351.1 - 5.2e-46 154.6 0.0 9.1e-18 64.1 0.0 3.7 3 0 0 3 3 3 3 Bromodomain Peptidase_M1 PF01433.20 KIY69351.1 - 5.8e-08 32.6 0.0 9.4e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 KIY69351.1 - 0.019 15.2 0.5 0.35 11.0 0.1 2.3 2 0 0 2 2 2 0 Peptidase M1 N-terminal domain LTV PF04180.14 KIY69352.1 - 2.2e-103 346.9 1.8 9e-93 312.0 9.0 2.0 1 1 1 2 2 2 2 Low temperature viability protein KMP11 PF03037.16 KIY69352.1 - 0.19 12.6 2.6 0.63 10.9 2.6 1.9 1 0 0 1 1 1 0 Kinetoplastid membrane protein 11 KIP1 PF07765.12 KIY69352.1 - 0.33 11.1 4.3 0.22 11.7 1.2 2.3 3 0 0 3 3 3 0 KIP1-like protein Ribosomal_S25 PF03297.15 KIY69353.1 - 2.2 8.5 7.3 5.7 7.2 7.3 1.6 1 0 0 1 1 1 0 S25 ribosomal protein zf-MYND PF01753.18 KIY69354.1 - 9.3e-11 41.6 10.2 1.8e-10 40.7 9.4 1.9 1 1 1 2 2 2 1 MYND finger VATC PF18716.1 KIY69354.1 - 1.1 9.1 7.1 4.9 7.1 7.1 2.2 1 1 0 1 1 1 0 Vms1-associating treble clef domain adh_short PF00106.25 KIY69355.1 - 1.3e-23 83.5 0.7 3.1e-20 72.5 0.3 2.2 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KIY69355.1 - 4.3e-11 42.8 0.0 6.1e-10 39.0 0.1 2.0 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIY69355.1 - 4.6e-05 23.4 0.1 7.9e-05 22.6 0.1 1.3 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.20 KIY69355.1 - 0.11 12.6 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Nup188 PF10487.9 KIY69357.1 - 3e-42 144.6 0.0 1.6e-40 138.9 0.0 3.1 2 1 0 2 2 2 1 Nucleoporin subcomplex protein binding to Pom34 Nup188_C PF18378.1 KIY69357.1 - 8.4e-07 28.1 1.0 3.8e-06 26.0 1.0 2.0 2 0 0 2 2 2 1 Nuclear pore protein NUP188 C-terminal domain Nup192 PF11894.8 KIY69357.1 - 0.00063 17.0 0.0 0.007 13.6 0.0 2.5 3 1 0 3 3 3 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 F-box-like PF12937.7 KIY69358.1 - 0.00012 21.9 0.1 0.00039 20.3 0.1 1.9 1 1 0 1 1 1 1 F-box-like Msap1 PF17077.5 KIY69358.1 - 0.051 12.8 0.0 0.073 12.2 0.0 1.2 1 0 0 1 1 1 0 Mitotic spindle associated protein SHE1 HLH PF00010.26 KIY69360.1 - 5.9e-13 48.6 1.8 5.9e-13 48.6 1.8 2.7 2 1 1 3 3 3 2 Helix-loop-helix DNA-binding domain DUF4553 PF15090.6 KIY69360.1 - 0.037 13.0 2.8 0.048 12.7 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4553) DUF632 PF04782.12 KIY69360.1 - 0.059 12.7 1.0 0.077 12.3 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF632) Mei5_like PF17021.5 KIY69360.1 - 0.84 9.7 4.3 0.26 11.3 0.4 1.9 1 1 1 2 2 2 0 Putative double-strand recombination repair-like AC_N PF16214.5 KIY69360.1 - 3.2 6.8 4.7 4.1 6.4 4.7 1.1 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region MASE2 PF05230.11 KIY69361.1 - 0.013 15.5 0.5 0.013 15.5 0.5 2.1 3 0 0 3 3 3 0 MASE2 domain DUF4234 PF14018.6 KIY69361.1 - 0.021 15.0 0.2 0.021 15.0 0.2 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4234) PEX11 PF05648.14 KIY69361.1 - 0.061 12.8 0.1 0.08 12.4 0.1 1.3 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) MPC PF03650.13 KIY69361.1 - 0.066 13.3 0.4 0.066 13.3 0.4 1.5 2 0 0 2 2 2 0 Mitochondrial pyruvate carriers Phage_holin_2_3 PF16080.5 KIY69361.1 - 0.33 10.8 6.1 1.4 8.7 2.3 2.8 3 0 0 3 3 3 0 Bacteriophage holin family HP1 TMEM237 PF15383.6 KIY69361.1 - 4.5 6.3 5.8 0.58 9.2 1.0 1.8 1 1 0 2 2 2 0 Transmembrane protein 237 HLH PF00010.26 KIY69362.1 - 7e-10 38.7 1.3 7e-10 38.7 1.3 2.4 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain FapA PF03961.13 KIY69362.1 - 0.08 11.5 0.9 0.11 11.1 0.9 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Cnn_1N PF07989.11 KIY69362.1 - 0.21 11.7 3.3 0.18 12.0 0.6 1.9 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 CENP-F_leu_zip PF10473.9 KIY69362.1 - 0.6 10.1 5.5 0.83 9.7 5.5 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CCDC-167 PF15188.6 KIY69362.1 - 1.1 9.6 4.7 2.9 8.3 4.6 1.7 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 DivIC PF04977.15 KIY69362.1 - 1.8 8.4 6.3 0.56 10.0 0.5 2.2 2 0 0 2 2 2 0 Septum formation initiator TBCA PF02970.16 KIY69363.1 - 1.2e-15 57.6 1.6 1.3e-15 57.5 1.3 1.3 1 1 0 1 1 1 1 Tubulin binding cofactor A Med11 PF10280.9 KIY69364.1 - 8.4e-09 36.0 0.0 9.5e-09 35.8 0.0 1.2 1 1 0 1 1 1 1 Mediator complex protein ABC_tran PF00005.27 KIY69365.1 - 2.2e-24 86.5 0.0 1.4e-14 54.8 0.0 2.8 3 0 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 KIY69365.1 - 3.4e-07 30.4 1.8 0.063 13.1 0.2 3.2 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 KIY69365.1 - 0.00017 21.8 0.0 0.48 10.7 0.0 2.7 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 KIY69365.1 - 0.0058 16.4 0.0 0.014 15.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain NACHT PF05729.12 KIY69365.1 - 0.046 13.6 0.0 0.11 12.4 0.0 1.7 2 0 0 2 2 2 0 NACHT domain DUF3584 PF12128.8 KIY69365.1 - 0.067 10.7 0.0 0.093 10.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Ploopntkinase1 PF18748.1 KIY69365.1 - 0.096 12.2 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase1 SMC_N PF02463.19 KIY69365.1 - 0.12 11.9 0.0 14 5.1 0.0 2.3 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain GDP_Man_Dehyd PF16363.5 KIY69366.1 - 5.6e-47 160.7 0.0 4.4e-46 157.8 0.0 1.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KIY69366.1 - 5.1e-41 140.7 0.0 7.1e-41 140.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KIY69366.1 - 5.7e-11 41.9 0.0 4e-07 29.3 0.0 3.0 2 1 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KIY69366.1 - 1.5e-10 40.7 0.0 7.5e-10 38.4 0.0 1.9 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KIY69366.1 - 5.3e-09 35.6 0.0 3.9e-08 32.8 0.0 2.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 KIY69366.1 - 6.2e-08 32.8 0.0 6.5e-07 29.4 0.0 2.1 1 1 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 KIY69366.1 - 3.1e-06 26.6 0.0 8.7e-06 25.1 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.25 KIY69366.1 - 0.00074 19.0 0.1 0.0031 17.0 0.1 1.9 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.6 KIY69366.1 - 0.0067 16.3 0.0 0.34 10.8 0.0 2.3 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KIY69367.1 - 1.2e-44 153.0 0.0 6.8e-44 150.6 0.0 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KIY69367.1 - 1.6e-40 139.1 0.0 2.6e-40 138.4 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KIY69367.1 - 4.4e-11 42.3 0.0 7.6e-08 31.7 0.0 3.2 2 1 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KIY69367.1 - 9.8e-09 34.7 0.0 2.6e-08 33.3 0.0 1.6 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KIY69367.1 - 1.3e-08 34.3 0.2 9.7e-08 31.5 0.1 2.5 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 KIY69367.1 - 8.8e-07 28.3 0.0 2.3e-06 27.0 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein KR PF08659.10 KIY69367.1 - 2.1e-06 27.8 0.0 9.8e-06 25.6 0.0 2.0 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KIY69367.1 - 0.0051 16.7 0.0 0.097 12.6 0.0 2.3 1 1 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 KIY69367.1 - 0.031 13.7 0.1 0.3 10.5 0.0 2.0 1 1 1 2 2 2 0 short chain dehydrogenase zf-C3HC4_3 PF13920.6 KIY69368.1 - 3.9e-08 33.0 7.5 8.1e-08 32.0 7.5 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KIY69368.1 - 1.4e-05 24.8 7.9 5.3e-05 23.0 7.9 2.0 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KIY69368.1 - 2.2e-05 24.2 7.3 8.5e-05 22.3 7.5 1.8 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIY69368.1 - 0.00015 21.7 10.0 0.00035 20.5 10.0 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KIY69368.1 - 0.00015 22.0 9.6 0.00024 21.3 9.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KIY69368.1 - 0.0003 20.8 5.7 0.0003 20.8 5.7 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KIY69368.1 - 0.00063 19.5 4.7 0.00063 19.5 4.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KIY69368.1 - 0.29 11.3 9.2 0.95 9.7 9.3 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF755 PF05501.11 KIY69368.1 - 1.9 8.7 9.8 3.3 8.0 9.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Pellino PF04710.14 KIY69368.1 - 9.7 4.7 8.0 0.23 10.1 1.8 1.4 2 0 0 2 2 2 0 Pellino CHAT PF12770.7 KIY69369.1 - 6.7e-35 120.9 0.0 8.6e-35 120.5 0.0 1.1 1 0 0 1 1 1 1 CHAT domain CENP-F_leu_zip PF10473.9 KIY69370.1 - 0.003 17.6 7.0 0.003 17.6 7.0 1.7 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4337 PF14235.6 KIY69370.1 - 0.019 15.1 4.2 0.039 14.1 4.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) FlxA PF14282.6 KIY69370.1 - 0.12 12.4 4.1 0.27 11.2 4.1 1.6 1 0 0 1 1 1 0 FlxA-like protein EMP24_GP25L PF01105.24 KIY69370.1 - 0.12 12.3 0.3 0.21 11.5 0.3 1.3 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Mgr1 PF08602.10 KIY69370.1 - 0.18 10.6 1.1 0.38 9.5 1.1 1.6 1 1 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit DUF3450 PF11932.8 KIY69370.1 - 0.21 10.9 3.8 0.32 10.2 3.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF4355 PF14265.6 KIY69370.1 - 0.3 11.3 8.3 0.34 11.1 6.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) DivIC PF04977.15 KIY69370.1 - 2.7 7.8 6.3 3.3 7.6 4.4 2.1 1 1 1 2 2 2 0 Septum formation initiator TSC22 PF01166.18 KIY69370.1 - 2.9 8.3 5.6 0.85 10.0 2.3 1.8 2 0 0 2 2 2 0 TSC-22/dip/bun family Spc7 PF08317.11 KIY69370.1 - 3 6.6 8.8 4.5 6.1 8.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein ZapB PF06005.12 KIY69370.1 - 3.3 8.2 10.6 4.2 7.9 9.3 1.8 1 1 0 1 1 1 0 Cell division protein ZapB Het-C PF07217.11 KIY69371.1 - 9.7e-213 707.7 0.0 1.3e-212 707.3 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C DUF4573 PF15140.6 KIY69371.1 - 0.048 13.5 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4573) DUF4175 PF13779.6 KIY69371.1 - 5.5 4.8 7.1 9.6 4.0 7.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Glyco_hydro_114 PF03537.13 KIY69372.1 - 1.1e-46 159.0 2.0 1.4e-46 158.7 2.0 1.0 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 Optomotor-blind PF11078.8 KIY69372.1 - 0.023 15.2 0.1 0.042 14.4 0.1 1.4 1 0 0 1 1 1 0 Optomotor-blind protein N-terminal region DUF2992 PF11208.8 KIY69373.1 - 0.011 16.0 1.2 11 6.3 2.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2992) Tup_N PF08581.10 KIY69373.1 - 0.24 11.7 6.0 0.18 12.1 4.1 1.8 1 1 1 2 2 2 0 Tup N-terminal Chitin_synth_1 PF01644.17 KIY69374.1 - 3.5e-72 241.7 0.4 5.7e-72 241.0 0.4 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KIY69374.1 - 4e-27 94.0 0.0 1.6e-26 92.0 0.1 2.0 2 0 0 2 2 2 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KIY69374.1 - 1e-25 90.4 1.7 3.8e-21 75.3 0.0 2.3 1 1 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KIY69374.1 - 2.2e-06 27.7 10.1 2.1e-05 24.5 10.1 2.5 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KIY69374.1 - 0.016 15.1 0.0 0.03 14.2 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Phage_holin_3_6 PF07332.11 KIY69376.1 - 1.2 9.2 10.4 0.43 10.6 3.6 2.9 2 1 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Myc_N PF01056.18 KIY69378.1 - 0.0091 15.9 2.7 0.0091 15.9 2.7 1.4 1 1 0 1 1 1 1 Myc amino-terminal region MPS2 PF17060.5 KIY69378.1 - 0.29 10.3 2.7 0.46 9.7 2.7 1.2 1 0 0 1 1 1 0 Monopolar spindle protein 2 Swi5 PF07061.11 KIY69378.1 - 1.3 9.1 4.1 0.71 10.0 0.7 2.0 1 1 1 2 2 2 0 Swi5 F-box-like PF12937.7 KIY69379.1 - 7.6e-06 25.7 0.0 4.7e-05 23.2 0.0 2.5 1 1 0 1 1 1 1 F-box-like LSDAT_prok PF18171.1 KIY69379.1 - 0.14 11.4 0.0 5.4 6.2 0.0 2.1 2 0 0 2 2 2 0 SLOG in TRPM, prokaryote F-box-like PF12937.7 KIY69380.1 - 3.8e-05 23.5 0.0 8.5e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 F-box-like Pkinase PF00069.25 KIY69381.1 - 9.6e-26 90.7 0.0 1.2e-25 90.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY69381.1 - 3.3e-13 49.5 0.0 4.1e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIY69381.1 - 6e-08 31.9 0.0 8.2e-08 31.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KIY69381.1 - 0.0022 18.0 0.0 0.018 14.9 0.0 2.2 3 0 0 3 3 3 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 KIY69381.1 - 0.076 12.0 0.1 0.11 11.5 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DDE_3 PF13358.6 KIY69383.1 - 1.7e-08 34.3 0.1 2.3e-08 33.9 0.1 1.3 1 1 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KIY69384.1 - 1.3e-07 31.5 0.0 1.5e-07 31.3 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.6 KIY69385.1 - 8.8e-06 25.7 2.2 1.5e-05 24.9 1.9 1.6 1 1 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.6 KIY69385.1 - 7.6e-05 22.8 4.5 0.00011 22.2 4.5 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_38 PF13936.6 KIY69385.1 - 0.00031 20.4 0.3 0.0005 19.8 0.3 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 KIY69385.1 - 0.0013 18.5 1.0 0.0022 17.7 1.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain TrmB PF01978.19 KIY69385.1 - 0.011 15.6 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Sigma70_r4_2 PF08281.12 KIY69385.1 - 0.018 14.7 0.0 0.032 13.9 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_IclR PF09339.10 KIY69385.1 - 0.036 13.9 0.0 0.082 12.7 0.0 1.6 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_AraC PF00165.23 KIY69385.1 - 0.063 13.4 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family SnoaL_2 PF12680.7 KIY69385.1 - 0.085 13.5 0.0 0.14 12.8 0.0 1.3 1 1 0 1 1 1 0 SnoaL-like domain Pkinase PF00069.25 KIY69386.1 - 4e-26 92.0 0.0 4.9e-26 91.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY69386.1 - 3.8e-13 49.3 0.0 4.6e-13 49.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIY69386.1 - 1.5e-08 33.9 0.1 1.9e-08 33.5 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KIY69386.1 - 0.0024 17.9 0.0 0.018 14.9 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 KIY69386.1 - 0.1 11.6 0.1 0.14 11.1 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase CDC27 PF09507.10 KIY69387.1 - 0.051 12.9 6.1 0.073 12.4 6.1 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 NIF PF03031.18 KIY69388.1 - 1.6e-21 76.7 0.1 1.9e-20 73.2 0.0 2.4 2 1 0 2 2 2 1 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.7 KIY69388.1 - 1.3e-09 37.8 0.1 3.1e-09 36.7 0.1 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 KIY69388.1 - 2.9e-09 37.2 0.0 5.8e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 KIY69388.1 - 5.6e-05 23.4 0.1 0.00013 22.2 0.1 1.6 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain BRCT_2 PF16589.5 KIY69388.1 - 0.017 15.5 0.0 0.036 14.5 0.0 1.5 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain Ndc1_Nup PF09531.10 KIY69388.1 - 0.15 10.8 0.9 0.26 9.9 0.9 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Ntox5 PF15543.6 KIY69388.1 - 0.16 11.8 0.0 0.41 10.5 0.0 1.7 1 0 0 1 1 1 0 Bacterial toxin 5 Piwi PF02171.17 KIY69389.1 - 1.8e-69 234.3 0.0 2.7e-69 233.7 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 KIY69389.1 - 6.2e-11 43.1 0.0 1.2e-10 42.2 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 KIY69389.1 - 2.8e-05 23.7 0.0 8e-05 22.2 0.0 1.9 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoMid PF16487.5 KIY69389.1 - 0.001 19.3 0.0 0.0034 17.6 0.0 2.0 1 0 0 1 1 1 1 Mid domain of argonaute RBD-FIP PF09457.10 KIY69389.1 - 0.078 12.9 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 FIP domain VRR_NUC PF08774.11 KIY69390.1 - 0.0064 16.6 0.0 0.015 15.3 0.0 1.6 1 1 0 1 1 1 1 VRR-NUC domain Homeodomain PF00046.29 KIY69391.1 - 1.7e-29 101.4 4.8 1.5e-15 56.7 0.8 2.4 2 0 0 2 2 2 2 Homeodomain Homeobox_KN PF05920.11 KIY69391.1 - 2.6e-06 27.2 2.8 0.054 13.4 0.0 3.1 3 0 0 3 3 3 2 Homeobox KN domain YdaS_antitoxin PF15943.5 KIY69391.1 - 0.00055 19.7 0.1 0.11 12.4 0.0 2.3 2 0 0 2 2 2 2 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HOCHOB PF17943.1 KIY69391.1 - 0.0014 19.3 0.0 0.64 10.7 0.0 2.3 2 0 0 2 2 2 2 Homeobox-cysteine loop-homeobox DUF4129 PF13559.6 KIY69391.1 - 0.076 13.3 1.0 0.3 11.4 0.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4129) Fumble PF03630.14 KIY69392.1 - 2.3e-130 434.6 0.0 2.9e-130 434.3 0.0 1.1 1 0 0 1 1 1 1 Fumble Adaptin_N PF01602.20 KIY69393.1 - 1.5e-112 376.9 0.0 2.1e-112 376.3 0.0 1.2 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 KIY69393.1 - 1.8e-54 184.0 1.4 4.3e-54 182.8 1.4 1.7 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 KIY69393.1 - 1.9e-34 118.3 0.0 4.4e-34 117.1 0.0 1.7 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 KIY69393.1 - 8.4e-16 58.1 0.5 1.1e-08 35.3 0.0 5.7 2 2 6 8 8 8 4 HEAT repeats Cnd1 PF12717.7 KIY69393.1 - 3e-07 30.6 2.8 0.087 12.9 0.1 4.4 3 1 0 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KIY69393.1 - 0.0053 16.9 4.3 7.5 7.1 0.1 5.5 5 0 0 5 5 5 1 HEAT repeat HEAT_PBS PF03130.16 KIY69393.1 - 0.16 12.7 0.9 37 5.4 0.0 5.0 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat An_peroxidase PF03098.15 KIY69396.1 - 5e-09 35.3 0.1 0.00041 19.1 0.0 2.8 2 1 1 3 3 3 2 Animal haem peroxidase Pec_lyase_C PF00544.19 KIY69399.1 - 1.7e-35 122.5 7.9 2.3e-35 122.1 7.9 1.1 1 0 0 1 1 1 1 Pectate lyase ADH_zinc_N PF00107.26 KIY69400.1 - 4.2e-30 104.4 0.3 6.5e-30 103.8 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KIY69400.1 - 4.3e-17 63.4 0.1 6.8e-17 62.8 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIY69400.1 - 2.1e-10 40.5 0.0 5.2e-09 36.0 0.0 2.7 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain UBN_AB PF14075.6 KIY69401.1 - 9.7e-38 130.0 0.0 1.7e-37 129.3 0.0 1.3 1 0 0 1 1 1 1 Ubinuclein conserved middle domain HUN PF08729.10 KIY69401.1 - 5.3e-15 55.1 0.6 1.4e-14 53.8 0.6 1.8 1 0 0 1 1 1 1 HPC2 and ubinuclein domain HECT PF00632.25 KIY69402.1 - 3.6e-92 309.1 0.0 5.8e-92 308.4 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.27 KIY69402.1 - 0.014 15.1 0.3 0.045 13.6 0.3 2.0 1 0 0 1 1 1 0 IQ calmodulin-binding motif UQ_con PF00179.26 KIY69403.1 - 3.5e-41 140.1 0.0 4.7e-41 139.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 KIY69403.1 - 0.038 13.8 0.0 0.065 13.1 0.0 1.3 1 0 0 1 1 1 0 UEV domain Exo_endo_phos PF03372.23 KIY69404.1 - 9.6e-16 58.0 0.0 2.5e-15 56.6 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.12 KIY69404.1 - 9.6e-06 25.6 1.6 0.0027 17.7 0.1 2.4 2 0 0 2 2 2 2 GRF zinc finger UIM PF02809.20 KIY69404.1 - 0.0074 16.1 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin interaction motif Exo_endo_phos_2 PF14529.6 KIY69404.1 - 0.055 13.3 0.0 3.7 7.4 0.0 2.6 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase DUF943 PF06092.12 KIY69404.1 - 0.16 11.6 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Enterobacterial putative membrane protein (DUF943) NAM-associated PF14303.6 KIY69404.1 - 3.1 8.5 9.6 7.2 7.3 9.5 1.6 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain Herpes_UL51 PF04540.13 KIY69405.1 - 0.072 12.8 0.7 0.13 11.9 0.7 1.3 1 0 0 1 1 1 0 Herpesvirus UL51 protein SURF6 PF04935.12 KIY69409.1 - 5.6e-42 143.8 37.0 5.6e-42 143.8 37.0 2.1 2 0 0 2 2 2 2 Surfeit locus protein 6 RRP14 PF15459.6 KIY69409.1 - 2.8e-16 59.8 7.7 2.8e-16 59.8 7.7 4.5 4 1 0 4 4 4 1 60S ribosome biogenesis protein Rrp14 CDH-cyt PF16010.5 KIY69410.1 - 1e-50 172.0 0.6 2.1e-50 170.9 0.6 1.5 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase GMC_oxred_C PF05199.13 KIY69410.1 - 3.6e-21 76.2 0.0 8.2e-21 75.0 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 KIY69410.1 - 7.2e-18 65.0 0.0 3.7e-17 62.6 0.0 2.2 1 1 1 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KIY69410.1 - 8.4e-07 28.4 0.0 8.4e-06 25.1 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KIY69410.1 - 6.1e-06 26.4 0.0 1.8e-05 24.8 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KIY69410.1 - 5.6e-05 22.6 0.1 0.0085 15.4 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KIY69410.1 - 0.00011 21.5 0.1 0.00019 20.8 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KIY69410.1 - 0.00011 21.5 0.1 0.00022 20.6 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIY69410.1 - 0.00031 20.4 0.0 0.0054 16.4 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KIY69410.1 - 0.0023 16.7 0.0 0.01 14.6 0.0 1.8 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 KIY69410.1 - 0.016 14.5 0.1 0.037 13.3 0.1 1.5 1 0 0 1 1 1 0 Thi4 family Amino_oxidase PF01593.24 KIY69410.1 - 0.034 13.4 0.0 0.081 12.2 0.0 1.6 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 KIY69410.1 - 0.2 10.7 0.1 0.29 10.1 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Pre-SET PF05033.16 KIY69411.1 - 9.5e-15 55.2 7.1 9.5e-15 55.2 7.1 2.6 2 1 0 2 2 2 1 Pre-SET motif SET PF00856.28 KIY69411.1 - 1e-14 55.3 0.4 2.5e-14 54.0 0.4 1.7 1 1 0 1 1 1 1 SET domain Sod_Fe_C PF02777.18 KIY69412.1 - 2e-33 114.6 0.0 3.4e-33 113.9 0.0 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KIY69412.1 - 4.4e-31 107.2 2.0 4.4e-31 107.2 2.0 2.0 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain DNA_pol_A_exo1 PF01612.20 KIY69413.1 - 1.1e-13 51.3 0.0 9.8e-10 38.4 0.0 2.2 2 0 0 2 2 2 2 3'-5' exonuclease Hydantoinase_B PF02538.14 KIY69414.1 - 4.2e-207 688.6 0.9 4.8e-207 688.5 0.9 1.0 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase PTR2 PF00854.21 KIY69416.1 - 2.4e-77 260.4 5.0 3.4e-77 259.9 5.0 1.2 1 0 0 1 1 1 1 POT family MFS_1 PF07690.16 KIY69416.1 - 4.2e-10 39.1 26.5 1.2e-08 34.3 19.0 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIY69416.1 - 0.00022 20.2 2.5 0.00022 20.2 2.5 3.1 3 1 1 4 4 4 2 Sugar (and other) transporter LETM1 PF07766.13 KIY69416.1 - 0.23 10.8 0.2 0.4 10.0 0.2 1.3 1 0 0 1 1 1 0 LETM1-like protein L51_S25_CI-B8 PF05047.16 KIY69417.1 - 1e-10 41.4 0.0 1.2e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Methyltransf_2 PF00891.18 KIY69417.1 - 0.14 11.4 0.0 0.14 11.4 0.0 1.1 1 0 0 1 1 1 0 O-methyltransferase domain RGS PF00615.19 KIY69419.1 - 1.1e-09 38.5 0.9 0.00016 21.9 0.3 2.9 2 1 0 2 2 2 2 Regulator of G protein signaling domain Fox-1_C PF12414.8 KIY69419.1 - 0.073 13.5 0.1 0.17 12.3 0.1 1.6 1 0 0 1 1 1 0 Calcitonin gene-related peptide regulator C terminal SGL PF08450.12 KIY69420.1 - 1.2e-30 106.9 0.0 2.2e-30 106.1 0.0 1.4 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 KIY69420.1 - 2.2e-06 27.7 0.0 1.3e-05 25.2 0.0 2.3 2 1 0 2 2 2 1 Strictosidine synthase Arylesterase PF01731.20 KIY69420.1 - 3.5e-06 27.1 0.0 3.9e-05 23.8 0.0 2.6 1 1 1 2 2 2 1 Arylesterase PD40 PF07676.12 KIY69420.1 - 0.015 15.2 0.1 0.065 13.2 0.0 2.1 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Glyco_hydro_88 PF07470.13 KIY69421.1 - 2.4e-65 220.9 9.5 2.9e-65 220.6 9.5 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Glyco_hydro_127 PF07944.12 KIY69421.1 - 0.01 14.4 0.8 0.022 13.3 0.6 1.5 1 1 0 1 1 1 0 Beta-L-arabinofuranosidase, GH127 Glyco_hydro_76 PF03663.14 KIY69421.1 - 0.047 13.2 14.0 2.8 7.4 0.4 3.8 2 1 1 3 3 3 0 Glycosyl hydrolase family 76 Hfx_Cass5 PF18287.1 KIY69421.1 - 0.11 12.8 0.4 2.5 8.3 0.1 2.4 1 1 1 2 2 2 0 Integron Cassette Protein Hfx_Cass5 HMG_box PF00505.19 KIY69423.1 - 4.5e-14 52.6 8.8 2.6e-07 30.9 0.0 3.0 3 1 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.10 KIY69423.1 - 2.7e-10 40.7 2.6 0.00036 21.1 0.7 2.6 2 0 0 2 2 2 2 HMG-box domain DUF1731 PF08338.11 KIY69424.1 - 0.058 13.2 0.1 0.14 12.0 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1731) PfkB PF00294.24 KIY69424.1 - 0.21 10.9 0.0 0.32 10.3 0.0 1.2 1 0 0 1 1 1 0 pfkB family carbohydrate kinase WD40 PF00400.32 KIY69425.1 - 2.4e-55 183.2 17.3 4.4e-08 33.7 0.0 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.10 KIY69425.1 - 5.8e-26 90.6 7.4 8.9e-26 90.0 7.4 1.3 1 0 0 1 1 1 1 Tup N-terminal ANAPC4_WD40 PF12894.7 KIY69425.1 - 2.1e-18 66.4 0.1 0.00065 20.0 0.0 6.0 1 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KIY69425.1 - 7.8e-09 35.3 0.0 0.061 12.6 0.0 5.3 5 1 0 5 5 5 3 WD40-like domain Ge1_WD40 PF16529.5 KIY69425.1 - 2.2e-06 26.9 1.0 1.3 7.9 0.0 4.9 2 2 4 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIY69425.1 - 0.0003 20.6 0.5 1.3 9.0 0.0 5.0 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 KIY69425.1 - 0.00051 18.7 2.4 0.044 12.3 0.1 3.2 2 2 1 3 3 3 1 Cytochrome D1 heme domain Nup160 PF11715.8 KIY69425.1 - 0.0049 15.6 0.2 0.58 8.7 0.0 3.4 3 1 1 4 4 4 1 Nucleoporin Nup120/160 Nbas_N PF15492.6 KIY69425.1 - 0.013 14.8 0.1 7.8 5.7 0.0 3.1 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal VID27 PF08553.10 KIY69425.1 - 0.022 13.8 0.4 3.3 6.7 0.0 3.2 3 1 0 4 4 4 0 VID27 C-terminal WD40-like domain OEP PF02321.18 KIY69425.1 - 0.77 9.5 3.6 1.3 8.8 3.6 1.3 1 0 0 1 1 1 0 Outer membrane efflux protein STE3 PF02076.15 KIY69427.1 - 2e-71 240.6 19.0 2.3e-71 240.4 19.0 1.0 1 0 0 1 1 1 1 Pheromone A receptor BCS1_N PF08740.11 KIY69428.1 - 1.3e-38 132.8 4.1 1.3e-38 132.8 4.1 2.0 2 0 0 2 2 2 1 BCS1 N terminal AAA PF00004.29 KIY69428.1 - 7e-17 62.1 0.0 1.1e-15 58.3 0.0 2.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KIY69428.1 - 0.003 18.0 0.0 0.0078 16.6 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.13 KIY69428.1 - 0.01 15.0 0.0 0.023 13.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RuvB_N PF05496.12 KIY69428.1 - 0.046 13.5 0.0 0.093 12.5 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KIY69428.1 - 0.048 14.2 1.3 0.2 12.2 0.0 2.6 3 0 0 3 3 3 0 AAA domain Aconitase PF00330.20 KIY69429.1 - 2.8e-150 501.3 0.1 3.8e-150 500.9 0.1 1.2 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KIY69429.1 - 1.5e-42 145.0 0.0 2.9e-42 144.1 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain HisKA PF00512.25 KIY69430.1 - 0.68 10.0 2.6 1.2 9.2 0.2 2.6 3 0 0 3 3 3 0 His Kinase A (phospho-acceptor) domain Meckelin PF09773.9 KIY69430.1 - 3.6 5.6 7.6 5.3 5.0 7.6 1.2 1 0 0 1 1 1 0 Meckelin (Transmembrane protein 67) cEGF PF12662.7 KIY69430.1 - 5.6 7.0 6.8 22 5.1 0.1 3.0 2 0 0 2 2 2 0 Complement Clr-like EGF-like Sugar_tr PF00083.24 KIY69431.1 - 1.7e-102 343.7 25.3 1.9e-102 343.5 25.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY69431.1 - 5.5e-29 101.2 51.2 3.7e-28 98.5 26.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PUCC PF03209.15 KIY69431.1 - 0.00049 19.2 9.3 0.00049 19.2 9.3 2.0 2 1 0 2 2 2 1 PUCC protein Pyr_redox_2 PF07992.14 KIY69432.1 - 6.3e-51 173.4 0.0 9.4e-51 172.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIY69432.1 - 6.6e-09 36.2 0.0 1.8e-07 31.6 0.0 2.9 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KIY69432.1 - 0.092 12.0 0.0 5.9 6.0 0.0 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KIY69432.1 - 0.12 12.4 0.6 4.1 7.4 0.1 3.0 2 1 0 2 2 2 0 FAD-NAD(P)-binding Ferric_reduct PF01794.19 KIY69433.1 - 1.3e-18 67.4 8.3 1.3e-18 67.4 8.3 1.8 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KIY69433.1 - 1e-11 44.8 0.0 1.8e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 KIY69433.1 - 4e-06 27.0 0.0 0.0014 18.8 0.0 2.2 1 1 0 2 2 2 2 Ferric reductase NAD binding domain DUF4405 PF14358.6 KIY69433.1 - 0.015 15.8 0.2 0.072 13.6 0.2 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4405) DUF2985 PF11204.8 KIY69433.1 - 0.032 14.4 0.1 0.1 12.7 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2985) DUF3533 PF12051.8 KIY69434.1 - 2e-90 303.5 13.8 2.3e-90 303.2 13.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) DUF1201 PF06716.11 KIY69434.1 - 0.063 13.3 0.6 0.36 10.9 0.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1201) DUF1970 PF09301.10 KIY69434.1 - 0.083 13.1 0.1 0.24 11.6 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1970) Pkinase PF00069.25 KIY69435.1 - 1.1e-72 244.6 0.0 1.3e-72 244.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY69435.1 - 6.8e-35 120.6 0.0 9.3e-35 120.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 KIY69435.1 - 2.5e-13 50.5 3.5 7.8e-13 48.9 2.9 2.2 2 0 0 2 2 2 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 KIY69435.1 - 1.8e-05 23.8 0.0 2.7e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KIY69435.1 - 0.0034 16.8 0.0 0.0072 15.7 0.0 1.5 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 KIY69435.1 - 0.047 13.3 0.0 1.3 8.6 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KIY69435.1 - 0.12 12.3 0.1 0.37 10.7 0.1 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 KIY69435.1 - 0.21 10.9 0.0 0.34 10.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Paf67 PF10255.9 KIY69436.1 - 3.5e-167 556.5 0.0 4.6e-167 556.1 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_16 PF13432.6 KIY69436.1 - 0.0072 17.0 0.0 1.3 9.8 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 KIY69436.1 - 0.014 15.4 0.0 0.13 12.5 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat CSN8_PSD8_EIF3K PF10075.9 KIY69436.1 - 0.068 13.2 0.5 9.4 6.2 0.0 2.8 3 0 0 3 3 3 0 CSN8/PSMD8/EIF3K family TPR_1 PF00515.28 KIY69436.1 - 0.086 12.7 0.0 0.39 10.6 0.0 2.2 3 0 0 3 3 3 0 Tetratricopeptide repeat MBOAT_2 PF13813.6 KIY69437.1 - 2.6e-16 59.7 3.1 2.6e-16 59.7 3.1 2.2 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family Plavaka PF18759.1 KIY69438.1 - 1.7e-34 119.5 0.0 2.8e-34 118.8 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase BNR PF02012.20 KIY69438.1 - 0.45 10.7 4.2 0.2 11.8 0.2 2.7 2 0 0 2 2 2 0 BNR/Asp-box repeat DEC-1_N PF04625.13 KIY69439.1 - 2.5 7.0 13.5 0.052 12.6 6.1 1.7 1 1 0 2 2 2 0 DEC-1 protein, N-terminal region DUF966 PF06136.13 KIY69440.1 - 0.023 14.4 0.1 0.024 14.3 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) MIF4G_like_2 PF09090.11 KIY69445.1 - 6.5e-66 222.5 0.0 1.1e-65 221.8 0.0 1.4 1 0 0 1 1 1 1 MIF4G like MIF4G_like PF09088.11 KIY69445.1 - 4.4e-64 215.8 0.0 8e-64 214.9 0.0 1.5 1 0 0 1 1 1 1 MIF4G like O-FucT PF10250.9 KIY69447.1 - 0.011 15.5 0.1 0.015 15.0 0.1 1.2 1 0 0 1 1 1 0 GDP-fucose protein O-fucosyltransferase DAP3 PF10236.9 KIY69448.1 - 8.5e-61 205.8 0.0 1e-60 205.5 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.6 KIY69448.1 - 1.2e-05 25.7 0.0 2.2e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 KIY69448.1 - 0.004 17.1 0.0 0.01 15.8 0.0 1.6 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_7 PF12775.7 KIY69448.1 - 0.042 13.4 0.0 0.087 12.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_19 PF13245.6 KIY69448.1 - 0.048 14.0 0.0 0.12 12.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KIY69448.1 - 0.15 12.2 0.0 0.65 10.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain SUZ PF12752.7 KIY69449.1 - 3.2e-11 43.8 3.0 3.2e-11 43.8 3.0 2.8 3 0 0 3 3 3 1 SUZ domain Pkinase PF00069.25 KIY69450.1 - 7.3e-33 114.1 0.0 1e-32 113.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY69450.1 - 3.2e-12 46.3 0.0 7.8e-12 45.0 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY69450.1 - 0.0013 18.2 0.1 0.051 12.9 0.1 2.4 2 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KIY69450.1 - 0.0033 16.3 0.0 0.013 14.3 0.0 1.7 1 1 0 2 2 2 1 Fungal protein kinase RIO1 PF01163.22 KIY69450.1 - 0.019 14.6 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 KIY69450.1 - 0.053 12.9 0.0 0.085 12.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KIY69450.1 - 0.26 10.9 0.0 0.51 9.9 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Ribo_biogen_C PF04034.13 KIY69451.1 - 2.6e-52 175.9 0.0 3.5e-52 175.5 0.0 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 KIY69451.1 - 4.9e-15 55.1 0.1 8e-15 54.4 0.1 1.4 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI SAP PF02037.27 KIY69453.1 - 3e-05 23.7 0.7 6.7e-05 22.5 0.7 1.5 1 0 0 1 1 1 1 SAP domain Melibiase_C PF17801.1 KIY69457.1 - 4.8e-15 55.4 0.3 6.7e-15 54.9 0.3 1.2 1 0 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase_2 PF16499.5 KIY69457.1 - 0.0049 16.1 0.1 0.0083 15.3 0.1 1.4 1 0 0 1 1 1 1 Alpha galactosidase A F-box-like PF12937.7 KIY69458.1 - 6.4e-06 26.0 0.2 1.3e-05 25.0 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KIY69459.1 - 0.00013 21.8 3.5 0.00034 20.5 3.5 1.8 1 0 0 1 1 1 1 F-box-like Methyltransf_2 PF00891.18 KIY69460.1 - 8.1e-23 80.8 0.0 2.9e-22 79.0 0.0 1.8 1 1 0 1 1 1 1 O-methyltransferase domain Methyltransf_23 PF13489.6 KIY69460.1 - 0.00046 20.0 0.0 0.00087 19.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain HTH_IclR PF09339.10 KIY69460.1 - 0.042 13.7 0.0 0.15 11.9 0.0 1.9 1 0 0 1 1 1 0 IclR helix-turn-helix domain Dimerisation2 PF16864.5 KIY69460.1 - 0.098 12.6 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Dimerisation domain HTH_24 PF13412.6 KIY69460.1 - 0.29 10.7 2.2 0.39 10.3 0.1 2.3 2 1 1 3 3 3 0 Winged helix-turn-helix DNA-binding RSN1_7TM PF02714.15 KIY69462.1 - 7.1e-76 255.1 22.7 7.3e-76 255.1 21.4 1.7 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KIY69462.1 - 4.4e-37 127.3 0.2 4.4e-37 127.3 0.2 2.7 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KIY69462.1 - 3.2e-36 125.2 0.0 4.8e-36 124.6 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter FLILHELTA PF10306.9 KIY69464.1 - 8.1e-11 42.2 0.0 1.2e-10 41.6 0.0 1.2 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA DUF1279 PF06916.13 KIY69464.1 - 0.012 16.1 0.0 0.017 15.7 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1279) DNA_pol_B_thumb PF14791.6 KIY69465.1 - 9e-22 77.0 0.2 2.7e-21 75.5 0.2 1.9 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.6 KIY69465.1 - 4.1e-17 62.4 0.1 1.4e-16 60.7 0.0 2.0 2 0 0 2 2 2 1 DNA polymerase beta palm HHH_8 PF14716.6 KIY69465.1 - 6.2e-08 32.9 0.0 2.2e-07 31.1 0.0 2.0 1 0 0 1 1 1 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.9 KIY69465.1 - 3.7e-07 29.9 0.0 8.8e-07 28.7 0.0 1.6 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_5 PF14520.6 KIY69465.1 - 0.014 16.0 0.0 1.7 9.3 0.0 2.8 2 0 0 2 2 2 0 Helix-hairpin-helix domain IMS_C PF11799.8 KIY69465.1 - 0.09 13.5 0.0 0.23 12.2 0.0 1.7 1 0 0 1 1 1 0 impB/mucB/samB family C-terminal domain BRCT_2 PF16589.5 KIY69465.1 - 0.14 12.6 0.0 0.3 11.5 0.0 1.6 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain PDGF_N PF04692.13 KIY69465.1 - 7.3 7.4 7.5 15 6.5 4.9 2.7 2 1 0 2 2 2 0 Platelet-derived growth factor, N terminal region Actin PF00022.19 KIY69468.1 - 7.7e-85 284.9 0.0 1.1e-83 281.1 0.0 1.9 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KIY69468.1 - 0.019 13.8 0.0 2.1 7.1 0.0 2.3 2 1 0 2 2 2 0 MreB/Mbl protein Spore_coat_CotO PF14153.6 KIY69469.1 - 0.0086 16.0 6.9 0.43 10.5 4.4 2.2 2 0 0 2 2 2 2 Spore coat protein CotO NPR3 PF03666.13 KIY69469.1 - 3.4 6.4 9.9 0.13 11.0 3.3 1.8 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 MDM10 PF12519.8 KIY69469.1 - 3.7 6.3 7.1 0.37 9.6 2.4 1.7 2 0 0 2 2 2 0 Mitochondrial distribution and morphology protein 10 Harakiri PF15196.6 KIY69469.1 - 4.6 7.8 6.0 1.2 9.6 1.3 2.1 2 0 0 2 2 2 0 Activator of apoptosis harakiri Pet100 PF09803.9 KIY69469.1 - 5.5 7.6 9.7 0.075 13.6 1.3 2.1 2 0 0 2 2 2 0 Pet100 RNA_pol_Rpc4 PF05132.14 KIY69469.1 - 8.6 6.8 6.8 0.98 9.8 1.9 1.9 2 0 0 2 2 2 0 RNA polymerase III RPC4 Ribosomal_L35Ae PF01247.18 KIY69470.1 - 3e-44 149.1 0.3 3.4e-44 148.9 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 KIY69470.1 - 0.0036 17.5 0.0 1.8 8.8 0.0 2.1 2 0 0 2 2 2 2 RimM N-terminal domain Calici_MSP PF05752.11 KIY69470.1 - 0.095 12.5 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Calicivirus minor structural protein Acyl-CoA_dh_N PF02771.16 KIY69471.1 - 1.1e-28 100.1 0.0 1.8e-28 99.4 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 KIY69471.1 - 2.6e-23 82.9 0.0 5e-23 82.0 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KIY69471.1 - 1.5e-19 69.9 0.0 3.1e-19 69.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KIY69471.1 - 0.00012 22.4 0.2 0.00038 20.8 0.2 1.8 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyclin_N PF00134.23 KIY69472.1 - 3.9e-10 39.6 0.0 6.3e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 KIY69472.1 - 6.6e-07 29.8 0.0 1.5e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 Cyclin Acetyltransf_1 PF00583.25 KIY69473.1 - 9.4e-08 32.3 0.0 1.3e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KIY69473.1 - 0.00016 21.6 0.0 0.00028 20.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 KIY69473.1 - 0.00023 21.5 0.0 0.00044 20.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KIY69473.1 - 0.00098 19.3 0.0 0.0018 18.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KIY69473.1 - 0.0011 19.6 0.0 0.0015 19.2 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KIY69473.1 - 0.02 14.8 0.0 0.037 14.0 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain AAA_16 PF13191.6 KIY69474.1 - 0.0028 18.1 0.0 0.0052 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain Mating_N PF12731.7 KIY69474.1 - 0.16 12.1 0.0 0.29 11.2 0.0 1.4 1 0 0 1 1 1 0 Mating-type protein beta 1 Zeta_toxin PF06414.12 KIY69474.1 - 0.17 11.2 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_5 PF07728.14 KIY69474.1 - 0.2 11.7 0.0 0.64 10.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Rer1 PF03248.13 KIY69475.1 - 6.9e-77 257.0 1.4 8e-77 256.8 1.4 1.0 1 0 0 1 1 1 1 Rer1 family DUF4191 PF13829.6 KIY69475.1 - 0.11 11.8 0.9 6.8 6.0 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) UPF0029 PF01205.19 KIY69477.1 - 2e-27 95.6 0.0 3.1e-27 95.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 Terpene_synth_C PF03936.16 KIY69478.1 - 1.2e-05 24.8 0.0 1.6e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain ATP_Ca_trans_C PF12424.8 KIY69479.1 - 0.048 14.1 0.5 0.24 11.9 0.0 2.1 2 0 0 2 2 2 0 Plasma membrane calcium transporter ATPase C terminal zf-CCCH_2 PF14608.6 KIY69480.1 - 1.5e-11 44.3 41.3 5.3e-05 23.5 2.7 4.3 4 0 0 4 4 4 3 RNA-binding, Nab2-type zinc finger zf-C3H1 PF10650.9 KIY69480.1 - 0.012 15.4 9.6 1.9 8.3 0.1 3.7 3 0 0 3 3 3 0 Putative zinc-finger domain Omega-toxin PF06357.11 KIY69480.1 - 0.1 12.4 0.3 0.1 12.4 0.3 3.2 4 0 0 4 4 4 0 Omega-atracotoxin IMUP PF15761.5 KIY69482.1 - 0.2 12.4 6.0 4.6 8.0 1.6 2.4 2 0 0 2 2 2 0 Immortalisation up-regulated protein bZIP_1 PF00170.21 KIY69483.1 - 6.2e-09 35.8 10.6 1.1e-08 35.1 10.6 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KIY69483.1 - 3.4e-06 27.0 11.5 3.4e-06 27.0 11.5 1.6 2 0 0 2 2 2 1 Basic region leucine zipper ABC_tran_CTD PF16326.5 KIY69483.1 - 0.095 13.0 0.9 0.17 12.1 0.9 1.3 1 0 0 1 1 1 0 ABC transporter C-terminal domain TMEM70 PF06979.12 KIY69485.1 - 8.4e-05 23.0 1.8 0.00012 22.4 1.8 1.2 1 0 0 1 1 1 1 Assembly, mitochondrial proton-transport ATP synth complex Abhydrolase_1 PF00561.20 KIY69487.1 - 3e-09 36.9 0.0 5.3e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIY69487.1 - 8.6e-06 25.2 0.0 2.1e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KIY69487.1 - 0.1 12.1 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 Prolyl oligopeptidase family DUF3048 PF11258.8 KIY69487.1 - 0.15 12.2 0.3 0.64 10.1 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3048) N-terminal domain Plavaka PF18759.1 KIY69492.1 - 9.7e-112 373.4 0.2 1.3e-111 372.9 0.2 1.2 1 0 0 1 1 1 1 Plavaka transposase zf-C2H2 PF00096.26 KIY69492.1 - 0.72 10.4 5.1 0.23 12.0 0.4 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type Sigma70_ner PF04546.13 KIY69492.1 - 2.7 7.8 4.3 4.5 7.1 4.3 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region EPL1 PF10513.9 KIY69493.1 - 1e-20 74.7 0.2 2.3e-20 73.6 0.1 1.6 2 0 0 2 2 2 1 Enhancer of polycomb-like Cyclase PF04199.13 KIY69494.1 - 3.1e-28 98.7 0.1 3.8e-28 98.4 0.1 1.1 1 0 0 1 1 1 1 Putative cyclase APC_r PF05923.12 KIY69494.1 - 7 6.5 5.5 4.7 7.1 0.3 2.4 2 0 0 2 2 2 0 APC repeat BTB PF00651.31 KIY69495.1 - 1.2e-05 25.5 0.0 0.0062 16.8 0.0 2.4 2 0 0 2 2 2 2 BTB/POZ domain BTB PF00651.31 KIY69496.1 - 0.00023 21.4 0.0 0.00074 19.7 0.0 1.8 1 1 1 2 2 2 1 BTB/POZ domain DASH_Dad2 PF08654.10 KIY69496.1 - 0.04 14.3 0.1 0.063 13.7 0.1 1.3 1 0 0 1 1 1 0 DASH complex subunit Dad2 EcoEI_R_C PF08463.10 KIY69496.1 - 0.088 12.9 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 EcoEI R protein C-terminal CTP_transf_like PF01467.26 KIY69497.1 - 1e-25 90.6 0.0 1.4e-25 90.2 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase-like DUF1908 PF08926.11 KIY69497.1 - 0.031 13.4 0.0 0.044 12.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1908) AAA PF00004.29 KIY69498.1 - 3.8e-17 63.0 0.0 9.5e-17 61.7 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KIY69498.1 - 4.3e-09 37.0 0.0 3.3e-08 34.1 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain BAH PF01426.18 KIY69498.1 - 2.6e-07 30.5 0.0 1e-06 28.6 0.0 2.0 2 0 0 2 2 2 1 BAH domain AAA_22 PF13401.6 KIY69498.1 - 4.7e-07 30.2 0.0 8.9e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_lid_10 PF17872.1 KIY69498.1 - 8.8e-05 22.6 0.1 0.00023 21.2 0.1 1.6 1 0 0 1 1 1 1 AAA lid domain DUF2075 PF09848.9 KIY69498.1 - 0.00055 19.3 0.0 0.0011 18.3 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 KIY69498.1 - 0.0026 18.1 0.0 0.0057 17.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KIY69498.1 - 0.028 14.2 0.0 0.062 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain MetW PF07021.12 KIY69498.1 - 0.077 12.6 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW NACHT PF05729.12 KIY69498.1 - 0.1 12.5 0.0 0.33 10.9 0.0 1.8 1 1 0 1 1 1 0 NACHT domain CDC45 PF02724.14 KIY69498.1 - 0.68 8.2 3.9 1.2 7.4 3.9 1.3 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 KIY69498.1 - 1.8 6.7 4.0 2.5 6.2 4.0 1.2 1 0 0 1 1 1 0 Nop14-like family YL1 PF05764.13 KIY69498.1 - 7.6 6.6 8.8 2.3 8.2 3.8 2.4 2 0 0 2 2 2 0 YL1 nuclear protein Glyco_hydro_11 PF00457.17 KIY69499.1 - 0.033 13.8 0.2 0.24 11.0 0.2 2.0 1 1 0 1 1 1 0 Glycosyl hydrolases family 11 APH PF01636.23 KIY69500.1 - 6.8e-09 36.0 0.5 1.2e-08 35.2 0.5 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KIY69500.1 - 8.7e-07 28.7 0.0 1.3e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase ketoacyl-synt PF00109.26 KIY69501.1 - 3.5e-78 262.7 0.0 6.5e-78 261.8 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KIY69501.1 - 2.9e-51 174.9 0.0 4.9e-50 170.9 0.0 2.2 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KIY69501.1 - 1.7e-35 121.6 0.2 3.3e-35 120.6 0.2 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain SAT PF16073.5 KIY69501.1 - 1.1e-24 87.5 2.2 1.6e-22 80.4 0.0 2.8 2 1 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis PS-DH PF14765.6 KIY69501.1 - 1.9e-24 86.5 0.0 3.2e-24 85.7 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.25 KIY69501.1 - 1.9e-21 76.1 4.7 1.6e-10 41.2 0.1 3.2 3 0 0 3 3 3 2 Phosphopantetheine attachment site Thioesterase PF00975.20 KIY69501.1 - 1.3e-18 67.9 0.0 4.2e-18 66.3 0.0 1.8 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 KIY69501.1 - 7.2e-06 26.8 2.7 2e-05 25.3 0.0 2.9 3 0 0 3 3 3 1 Alpha/beta hydrolase family KAsynt_C_assoc PF16197.5 KIY69501.1 - 6.7e-05 23.3 0.0 0.00014 22.2 0.0 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 KIY69501.1 - 0.00038 19.9 0.1 0.0007 19.0 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain DUF2974 PF11187.8 KIY69501.1 - 0.08 12.5 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) HSP70 PF00012.20 KIY69502.1 - 3.6e-262 870.9 14.2 4.1e-262 870.7 14.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KIY69502.1 - 4.9e-14 51.9 6.5 6e-13 48.3 0.4 2.7 3 0 0 3 3 3 2 MreB/Mbl protein StbA PF06406.11 KIY69502.1 - 0.019 14.2 0.3 0.32 10.2 0.0 2.4 1 1 1 2 2 2 0 StbA protein FGGY_C PF02782.16 KIY69502.1 - 0.02 14.6 0.0 0.049 13.3 0.0 1.7 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 KIY69502.1 - 0.12 12.8 5.5 16 6.0 0.0 4.1 3 1 0 3 3 3 0 Cell division protein FtsA F-box-like PF12937.7 KIY69504.1 - 0.047 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 F-box-like adh_short PF00106.25 KIY69505.1 - 1.9e-41 141.7 0.0 3e-41 141.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIY69505.1 - 3.6e-28 98.7 0.0 4.8e-28 98.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIY69505.1 - 6.7e-11 42.4 0.5 1.9e-09 37.7 0.5 2.1 1 1 0 1 1 1 1 KR domain Na_H_Exchanger PF00999.21 KIY69505.1 - 0.0021 17.0 1.9 0.0034 16.2 1.9 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Epimerase PF01370.21 KIY69505.1 - 0.0054 16.2 0.0 0.013 15.0 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family SUR7 PF06687.12 KIY69506.1 - 2.9e-21 76.1 13.4 3.8e-21 75.7 13.4 1.1 1 0 0 1 1 1 1 SUR7/PalI family Bacteriocin_IId PF09221.10 KIY69506.1 - 0.073 13.3 1.3 0.073 13.3 1.3 2.0 2 0 0 2 2 2 0 Bacteriocin class IId cyclical uberolysin-like TcdA_TcdB_pore PF12920.7 KIY69506.1 - 0.21 9.8 3.1 0.27 9.4 3.1 1.1 1 0 0 1 1 1 0 TcdA/TcdB pore forming domain Zip PF02535.22 KIY69507.1 - 2.8e-56 191.2 14.1 6.8e-56 189.9 14.1 1.5 1 1 0 1 1 1 1 ZIP Zinc transporter Foie-gras_1 PF11817.8 KIY69509.1 - 3.8e-36 125.0 1.3 2.1e-33 116.0 0.4 2.9 2 1 0 2 2 2 1 Foie gras liver health family 1 Gryzun PF07919.12 KIY69509.1 - 6.7e-14 51.6 0.0 3.6e-09 35.9 0.0 2.4 2 1 0 2 2 2 2 Gryzun, putative trafficking through Golgi TPR_12 PF13424.6 KIY69509.1 - 0.00098 19.4 1.0 0.065 13.5 0.0 3.6 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KIY69509.1 - 0.0027 17.6 0.3 0.032 14.2 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TRAPPC10 PF12584.8 KIY69509.1 - 0.013 15.2 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 Trafficking protein particle complex subunit 10, TRAPPC10 TPR_8 PF13181.6 KIY69509.1 - 0.013 15.6 0.0 0.082 13.2 0.0 2.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Gryzun-like PF12742.7 KIY69509.1 - 0.035 14.1 0.0 0.066 13.2 0.0 1.4 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking TPR_1 PF00515.28 KIY69509.1 - 0.097 12.5 0.0 0.097 12.5 0.0 3.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Transglut_C PF00927.22 KIY69509.1 - 0.15 12.2 0.0 1 9.6 0.0 2.4 2 0 0 2 2 2 0 Transglutaminase family, C-terminal ig like domain TPR_2 PF07719.17 KIY69509.1 - 0.19 11.9 0.0 0.19 11.9 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4820 PF16091.5 KIY69509.1 - 0.19 11.0 0.0 0.35 10.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Prenyltransf PF01255.19 KIY69510.1 - 3.9e-73 245.7 0.0 4.9e-73 245.4 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase DUF262 PF03235.14 KIY69511.1 - 2.1e-14 54.2 1.7 6.9e-12 46.0 0.1 2.7 2 1 1 3 3 3 2 Protein of unknown function DUF262 PetG PF02529.15 KIY69512.1 - 0.81 9.6 3.2 0.84 9.5 0.9 2.2 2 0 0 2 2 2 0 Cytochrome B6-F complex subunit 5 SPX PF03105.19 KIY69512.1 - 1.9 8.3 7.6 2.8 7.8 7.6 1.2 1 0 0 1 1 1 0 SPX domain zf-C2H2 PF00096.26 KIY69513.1 - 6.2e-14 51.6 4.0 2.9e-06 27.4 0.9 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KIY69513.1 - 1.4e-11 44.3 2.5 7.6e-05 23.0 0.1 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KIY69513.1 - 7.5e-10 38.8 3.5 0.0001 22.9 0.6 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KIY69513.1 - 7.2e-06 25.7 2.6 0.00023 20.8 0.3 2.2 2 0 0 2 2 2 1 zinc-finger C2H2-type zf-BED PF02892.15 KIY69513.1 - 0.00028 20.8 1.0 0.038 14.0 0.1 2.2 2 0 0 2 2 2 1 BED zinc finger zf-H2C2_5 PF13909.6 KIY69513.1 - 0.00063 19.5 1.8 0.073 12.8 0.2 2.5 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 KIY69513.1 - 0.00076 19.4 2.3 0.0058 16.6 0.2 2.4 2 1 0 2 2 2 1 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KIY69513.1 - 0.0016 18.3 2.6 0.025 14.5 0.5 2.4 2 0 0 2 2 2 1 zinc-finger of a C2HC-type zf-met PF12874.7 KIY69513.1 - 0.011 16.1 0.4 0.036 14.5 0.2 2.0 2 0 0 2 2 2 0 Zinc-finger of C2H2 type C1_2 PF03107.16 KIY69513.1 - 0.013 15.7 1.3 0.074 13.4 1.3 1.9 1 1 0 1 1 1 0 C1 domain zf-C2H2_jaz PF12171.8 KIY69513.1 - 0.032 14.5 0.1 0.34 11.3 0.1 2.1 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DUF3268 PF11672.8 KIY69513.1 - 0.038 14.3 0.4 0.046 14.1 0.4 1.1 1 0 0 1 1 1 0 zinc-finger-containing domain Zn-ribbon_8 PF09723.10 KIY69513.1 - 0.09 12.9 0.4 13 6.0 0.0 2.2 2 0 0 2 2 2 0 Zinc ribbon domain FYVE PF01363.21 KIY69513.1 - 0.63 10.2 4.1 1.8 8.8 0.6 2.0 1 1 1 2 2 2 0 FYVE zinc finger zf-C2H2 PF00096.26 KIY69514.1 - 6.9e-06 26.2 0.1 6.9e-06 26.2 0.1 1.9 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIY69514.1 - 0.00017 22.1 0.2 0.00017 22.1 0.2 2.5 3 0 0 3 3 3 1 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KIY69514.1 - 0.00034 20.9 0.9 0.029 14.8 0.7 2.7 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KIY69514.1 - 0.014 15.7 0.1 0.033 14.5 0.1 1.7 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 KIY69514.1 - 0.049 13.6 0.1 0.081 12.9 0.1 1.3 1 0 0 1 1 1 0 zinc-finger of a C2HC-type PyrI_C PF02748.15 KIY69514.1 - 0.052 13.5 0.2 0.09 12.7 0.2 1.3 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain BTB PF00651.31 KIY69515.1 - 0.0011 19.1 0.0 0.0022 18.2 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain DUF3435 PF11917.8 KIY69516.1 - 0.063 12.2 1.2 0.089 11.7 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) Prp19 PF08606.11 KIY69516.1 - 0.14 12.2 2.6 0.26 11.3 2.6 1.4 1 0 0 1 1 1 0 Prp19/Pso4-like Ribosomal_L19e PF01280.20 KIY69517.1 - 4.6e-63 211.6 11.4 4.6e-63 211.6 11.4 1.8 2 0 0 2 2 2 1 Ribosomal protein L19e Lant_dehydr_C PF14028.6 KIY69517.1 - 0.0014 18.3 0.8 0.0014 18.3 0.8 1.4 1 1 0 1 1 1 1 Lantibiotic biosynthesis dehydratase C-term DUF349 PF03993.12 KIY69517.1 - 0.095 13.0 7.4 0.58 10.5 2.6 2.7 2 1 0 2 2 2 0 Domain of Unknown Function (DUF349) TAL_FSA PF00923.19 KIY69518.1 - 7.5e-93 311.0 0.0 8.9e-93 310.7 0.0 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Rtf2 PF04641.12 KIY69519.1 - 4.7e-74 249.1 0.8 5.6e-74 248.8 0.8 1.0 1 0 0 1 1 1 1 Rtf2 RING-finger zf-NOSIP PF15906.5 KIY69519.1 - 0.00033 20.7 0.0 0.00078 19.5 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-Nse PF11789.8 KIY69519.1 - 0.00052 19.8 0.2 0.086 12.7 0.0 2.9 3 0 0 3 3 3 1 Zinc-finger of the MIZ type in Nse subunit MRP-S31 PF15433.6 KIY69519.1 - 0.18 11.5 3.7 0.28 10.8 3.7 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 DUF1178 PF06676.11 KIY69519.1 - 1.4 9.3 6.0 3 8.2 6.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1178) Prok-RING_4 PF14447.6 KIY69519.1 - 5.3 7.0 6.9 3.6 7.5 0.1 3.0 4 0 0 4 4 4 0 Prokaryotic RING finger family 4 Tyr-DNA_phospho PF06087.12 KIY69520.1 - 1.9e-54 185.2 0.0 3.1e-54 184.5 0.0 1.2 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.6 KIY69520.1 - 0.016 15.1 0.0 0.09 12.7 0.0 2.1 2 0 0 2 2 2 0 PLD-like domain UIM PF02809.20 KIY69520.1 - 0.022 14.7 3.5 0.11 12.5 3.5 2.3 1 0 0 1 1 1 0 Ubiquitin interaction motif KorB_C PF06613.11 KIY69520.1 - 0.065 13.2 1.0 2.5 8.2 0.0 3.2 4 0 0 4 4 4 0 KorB C-terminal beta-barrel domain ALG11_N PF15924.5 KIY69521.1 - 3.3e-86 288.7 0.5 4.7e-86 288.2 0.5 1.2 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 KIY69521.1 - 6e-27 94.3 0.0 9.2e-27 93.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KIY69521.1 - 3.5e-14 53.4 0.1 6.8e-14 52.5 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KIY69521.1 - 0.00085 19.7 0.0 0.0019 18.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Steroid_dh PF02544.16 KIY69522.1 - 6.5e-33 113.8 0.1 1e-32 113.2 0.1 1.3 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase ubiquitin PF00240.23 KIY69522.1 - 8.7e-06 25.4 0.0 1.5e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Jiraiya PF15038.6 KIY69524.1 - 0.049 13.1 8.1 2 7.8 0.1 2.3 2 0 0 2 2 2 0 Jiraiya CcmH PF03918.14 KIY69524.1 - 0.26 10.6 0.0 0.26 10.6 0.0 1.7 2 0 0 2 2 2 0 Cytochrome C biogenesis protein Orai-1 PF07856.12 KIY69524.1 - 3 7.5 6.7 7.4 6.2 6.4 1.7 2 1 0 2 2 2 0 Mediator of CRAC channel activity BPD_transp_1 PF00528.22 KIY69524.1 - 7.6 6.2 16.3 6 6.6 1.6 2.4 2 0 0 2 2 2 0 Binding-protein-dependent transport system inner membrane component F-box-like PF12937.7 KIY69525.1 - 8.9e-06 25.5 1.4 2.3e-05 24.2 0.4 2.2 2 0 0 2 2 2 1 F-box-like CsbD PF05532.12 KIY69526.1 - 4.7e-12 45.6 14.4 9.4e-08 31.8 2.4 2.1 1 1 1 2 2 2 2 CsbD-like Pkinase PF00069.25 KIY69527.1 - 4.3e-37 127.9 0.0 4.9e-37 127.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY69527.1 - 2.7e-14 53.1 0.0 5.4e-14 52.1 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY69527.1 - 1.6e-07 30.9 0.0 1.8e-07 30.8 0.0 1.0 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KIY69527.1 - 0.019 14.4 0.0 0.026 13.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIY69527.1 - 0.024 14.6 0.0 0.086 12.8 0.0 1.8 2 1 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KIY69527.1 - 0.072 11.9 0.0 0.084 11.6 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Cpn60_TCP1 PF00118.24 KIY69528.1 - 8.8e-166 552.3 1.2 1e-165 552.1 1.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF627 PF04781.12 KIY69528.1 - 0.16 12.0 0.0 0.99 9.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF627) Ribosomal_S5_C PF03719.15 KIY69529.1 - 3.6e-15 55.2 0.0 7.6e-15 54.1 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 KIY69529.1 - 5.5e-11 42.3 0.2 1.4e-10 41.0 0.2 1.7 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain GPHH PF16905.5 KIY69529.1 - 0.22 11.3 0.4 19 5.1 0.0 3.0 3 0 0 3 3 3 0 Voltage-dependent L-type calcium channel, IQ-associated AMP-binding PF00501.28 KIY69530.1 - 2.3e-41 141.8 0.0 3.1e-41 141.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KIY69530.1 - 0.00076 19.3 0.0 0.0014 18.5 0.0 1.5 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus DUF4200 PF13863.6 KIY69531.1 - 0.37 11.2 8.9 0.69 10.3 8.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Spc24 PF08286.11 KIY69531.1 - 0.92 9.8 5.3 0.42 10.9 1.2 2.3 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 SOGA PF11365.8 KIY69531.1 - 1.7 9.8 6.1 1.6 9.9 2.4 2.4 2 0 0 2 2 2 0 Protein SOGA Fib_alpha PF08702.10 KIY69531.1 - 3.1 8.0 7.7 8.4 6.6 7.5 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family PIEZO PF15917.5 KIY69531.1 - 3.1 7.2 7.9 7.3 6.0 7.9 1.6 1 0 0 1 1 1 0 Piezo ERM PF00769.19 KIY69531.1 - 5.5 6.7 18.6 0.99 9.2 15.1 1.5 2 0 0 2 2 2 0 Ezrin/radixin/moesin family Fzo_mitofusin PF04799.13 KIY69531.1 - 6.9 6.2 7.0 5.4 6.5 0.3 2.2 1 1 1 2 2 2 0 fzo-like conserved region SMN PF06003.12 KIY69532.1 - 0.084 12.1 0.2 0.084 12.1 0.2 2.5 2 1 1 3 3 3 0 Survival motor neuron protein (SMN) Aminotran_5 PF00266.19 KIY69533.1 - 6.6e-14 51.6 0.0 4.2e-13 49.0 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KIY69533.1 - 2.3e-05 23.9 0.3 0.00079 18.8 0.1 2.2 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 KIY69533.1 - 6.1e-05 22.4 0.0 0.00011 21.5 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II PfkB PF00294.24 KIY69534.1 - 1.5e-65 221.5 0.9 1.8e-65 221.3 0.9 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase RCC1 PF00415.18 KIY69535.1 - 4.3e-26 91.3 14.8 2e-05 25.1 0.0 7.4 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KIY69535.1 - 2.9e-17 62.0 26.5 1.1e-08 34.6 0.1 7.6 8 1 0 8 8 8 5 Regulator of chromosome condensation (RCC1) repeat Use1 PF09753.9 KIY69536.1 - 1.1e-14 54.8 0.0 3.6e-13 49.8 0.0 2.1 2 0 0 2 2 2 2 Membrane fusion protein Use1 Mito_carr PF00153.27 KIY69538.1 - 7.4e-72 237.4 5.9 1.3e-25 89.1 0.0 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KIY69538.1 - 0.0027 16.9 0.5 0.91 8.6 0.0 3.0 1 1 1 3 3 3 2 Gammaproteobacterial serine protease Ribosomal_L18p PF00861.22 KIY69538.1 - 0.021 15.2 0.5 0.42 11.0 0.0 2.6 3 0 0 3 3 3 0 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast GCP_C_terminal PF04130.13 KIY69539.1 - 4.9e-52 177.3 0.0 1e-51 176.3 0.0 1.5 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KIY69539.1 - 0.00016 21.4 0.0 0.00027 20.7 0.0 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal SPT_ssu-like PF11779.8 KIY69540.1 - 4e-12 45.6 2.3 5.7e-12 45.1 2.3 1.2 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like SPT_ssu-like PF11779.8 KIY69541.1 - 6.3e-14 51.3 6.5 8.5e-14 50.9 6.5 1.2 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like DUF2367 PF10164.9 KIY69542.1 - 7.1e-06 26.5 4.9 2.5e-05 24.7 4.9 1.9 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2367) DUF2378 PF09536.10 KIY69542.1 - 0.17 11.7 0.0 0.25 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2378) Methyltransf_25 PF13649.6 KIY69543.1 - 1.9e-13 50.9 0.1 7.4e-13 49.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIY69543.1 - 5e-12 45.9 0.6 1.3e-11 44.5 0.2 1.6 1 1 1 2 2 2 1 Methyltransferase domain PrmA PF06325.13 KIY69543.1 - 1.2e-11 44.5 0.1 1.7e-11 44.1 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 KIY69543.1 - 3e-10 40.6 0.0 7.4e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIY69543.1 - 1.2e-08 34.9 0.0 3.3e-08 33.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KIY69543.1 - 1.5e-07 31.0 0.1 2.3e-07 30.4 0.1 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 KIY69543.1 - 6.1e-07 28.7 0.0 9.7e-07 28.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_12 PF08242.12 KIY69543.1 - 1.9e-06 28.5 0.0 3.7e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KIY69543.1 - 5.1e-06 26.1 0.2 8.9e-06 25.3 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 KIY69543.1 - 8.6e-05 22.5 0.0 0.00014 21.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIY69543.1 - 8.7e-05 22.0 0.1 0.00014 21.2 0.1 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 KIY69543.1 - 0.00057 19.7 0.1 0.0015 18.4 0.0 1.6 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.9 KIY69543.1 - 0.00094 19.0 0.1 0.0015 18.3 0.1 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_32 PF13679.6 KIY69543.1 - 0.0014 18.6 0.0 0.0026 17.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 KIY69543.1 - 0.0026 17.2 1.2 0.01 15.3 0.3 2.3 1 1 1 2 2 2 1 Tellurite resistance protein TehB FtsJ PF01728.19 KIY69543.1 - 0.0032 17.6 0.0 0.0056 16.8 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Cons_hypoth95 PF03602.15 KIY69543.1 - 0.0072 16.0 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_24 PF13578.6 KIY69543.1 - 0.052 14.6 0.0 0.11 13.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain PRMT5 PF05185.16 KIY69543.1 - 0.12 12.2 0.0 0.19 11.6 0.0 1.4 1 1 0 1 1 1 0 PRMT5 arginine-N-methyltransferase RhoGAP PF00620.27 KIY69544.1 - 4.4e-31 107.8 0.0 8e-31 106.9 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain Glyco_hydro_63 PF03200.16 KIY69545.1 - 1.5e-08 33.9 8.5 1.5e-06 27.3 1.1 3.9 3 1 0 3 3 3 2 Glycosyl hydrolase family 63 C-terminal domain Lac_bphage_repr PF06543.12 KIY69545.1 - 0.093 12.7 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 Lactococcus bacteriophage repressor P_C PF06640.11 KIY69546.1 - 0.57 10.3 4.2 1.3 9.1 4.2 1.6 1 0 0 1 1 1 0 P protein C-terminus BRCT_2 PF16589.5 KIY69547.1 - 3e-09 37.2 0.0 7.9e-09 35.8 0.0 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain VASt PF16016.5 KIY69548.1 - 3.2e-39 134.8 0.1 5.4e-39 134.1 0.1 1.4 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 KIY69548.1 - 7.1e-23 80.7 0.0 1.4e-22 79.7 0.0 1.5 1 0 0 1 1 1 1 GRAM domain CLZ PF16526.5 KIY69548.1 - 0.092 13.1 0.3 0.29 11.5 0.2 1.9 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels F-box-like PF12937.7 KIY69549.1 - 9.5e-06 25.4 0.4 9.5e-06 25.4 0.4 2.3 2 0 0 2 2 2 1 F-box-like SKN1 PF03935.15 KIY69552.1 - 5.6e-184 612.2 1.1 6.2e-184 612.1 1.1 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Transferase PF02458.15 KIY69553.1 - 1.5e-32 112.9 0.0 4.5e-32 111.3 0.0 1.6 1 1 0 1 1 1 1 Transferase family Condensation PF00668.20 KIY69553.1 - 0.033 12.9 0.0 0.36 9.4 0.0 1.9 2 0 0 2 2 2 0 Condensation domain GTP_EFTU PF00009.27 KIY69554.1 - 3e-18 66.1 0.0 6.3e-18 65.0 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KIY69554.1 - 4.2e-06 27.0 0.0 1.2e-05 25.6 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KIY69554.1 - 0.00028 21.2 1.2 0.0013 19.1 0.2 2.8 3 0 0 3 3 3 1 Elongation factor Tu domain 2 Mcl1_mid PF12341.8 KIY69555.1 - 8.4e-75 251.9 0.0 1.4e-72 244.6 0.0 3.1 3 0 0 3 3 3 1 Minichromosome loss protein, Mcl1, middle region WD40 PF00400.32 KIY69555.1 - 3.2e-15 56.2 6.4 0.0057 17.5 0.2 7.0 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY69555.1 - 5.6e-11 42.6 0.3 0.011 16.0 0.0 5.6 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain HPS3_N PF14761.6 KIY69555.1 - 0.029 13.9 0.1 5.4 6.5 0.1 2.4 2 0 0 2 2 2 0 Hermansky-Pudlak syndrome 3 eIF2A PF08662.11 KIY69555.1 - 0.082 12.8 0.2 2.5 8.0 0.0 2.6 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KIY69555.1 - 0.21 10.9 0.1 13 5.0 0.0 2.8 2 1 1 3 3 3 0 WD40-like domain RrnaAD PF00398.20 KIY69556.1 - 2.6e-21 75.9 0.0 1e-20 73.9 0.0 1.8 1 1 0 1 1 1 1 Ribosomal RNA adenine dimethylase p450 PF00067.22 KIY69557.1 - 1.8e-49 168.8 0.0 2.6e-49 168.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Ytca PF17090.5 KIY69558.1 - 0.016 15.7 0.3 0.016 15.7 0.3 2.7 2 1 1 3 3 3 0 Uncharacterised protein family RrnaAD PF00398.20 KIY69559.1 - 1.4e-57 194.8 0.0 1.7e-57 194.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 KIY69559.1 - 2e-07 31.6 0.0 4.3e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIY69559.1 - 2.4e-05 24.9 0.0 5.9e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KIY69559.1 - 4.6e-05 23.3 0.0 7.6e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 KIY69559.1 - 0.00013 21.8 0.0 0.00023 21.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIY69559.1 - 0.00032 21.4 0.0 0.00077 20.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KIY69559.1 - 0.00082 19.0 0.0 0.0023 17.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain CMAS PF02353.20 KIY69559.1 - 0.0015 17.9 0.0 0.0033 16.7 0.0 1.5 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.18 KIY69559.1 - 0.0035 16.7 0.0 0.0061 15.9 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain DREV PF05219.12 KIY69559.1 - 0.017 14.3 0.0 0.028 13.5 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Met_10 PF02475.16 KIY69559.1 - 0.021 14.6 0.1 0.18 11.5 0.0 2.1 2 0 0 2 2 2 0 Met-10+ like-protein Methyltransf_31 PF13847.6 KIY69559.1 - 0.023 14.5 0.0 0.035 13.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_28 PF02636.17 KIY69559.1 - 0.034 13.8 0.0 0.07 12.8 0.0 1.5 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Ubie_methyltran PF01209.18 KIY69559.1 - 0.037 13.4 0.0 0.059 12.7 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family NodS PF05401.11 KIY69559.1 - 0.052 13.2 0.0 0.091 12.4 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) PhyH PF05721.13 KIY69560.1 - 6.6e-46 157.2 0.0 8.1e-46 156.9 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) FRD2 PF03197.13 KIY69560.1 - 0.16 12.3 0.0 0.28 11.5 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage FRD2 protein PH_10 PF15411.6 KIY69561.1 - 1.7e-36 125.1 0.0 3.7e-36 124.1 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 KIY69561.1 - 7.6e-31 107.8 1.3 1.2e-30 107.1 1.3 1.4 1 0 0 1 1 1 1 RhoGEF domain PB1 PF00564.24 KIY69561.1 - 9.5e-18 63.9 0.0 2e-17 62.9 0.0 1.6 1 0 0 1 1 1 1 PB1 domain CDC24 PF06395.11 KIY69561.1 - 3.3e-11 43.3 0.0 6.2e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 CDC24 Calponin DDE_Tnp_1_4 PF13701.6 KIY69561.1 - 0.068 11.4 0.0 0.11 10.7 0.0 1.2 1 0 0 1 1 1 0 Transposase DDE domain group 1 CAP_GLY PF01302.25 KIY69562.1 - 1.9e-08 34.2 1.1 4e-07 29.9 0.8 2.6 2 0 0 2 2 2 1 CAP-Gly domain BTB PF00651.31 KIY69562.1 - 5.5e-08 33.0 0.0 1.1e-06 28.8 0.0 2.7 3 0 0 3 3 3 1 BTB/POZ domain Mpv17_PMP22 PF04117.12 KIY69563.1 - 2.2e-21 75.8 1.5 2.2e-21 75.8 1.5 1.6 2 0 0 2 2 2 1 Mpv17 / PMP22 family FA_desaturase PF00487.24 KIY69563.1 - 0.17 11.7 3.1 0.26 11.1 2.5 1.4 1 1 0 1 1 1 0 Fatty acid desaturase Claudin_3 PF06653.11 KIY69564.1 - 0.0065 16.4 1.3 0.0065 16.4 1.3 1.9 2 0 0 2 2 2 1 Tight junction protein, Claudin-like CsbD PF05532.12 KIY69565.1 - 4.9e-12 45.5 2.8 5.2e-06 26.3 3.1 2.1 1 1 1 2 2 2 2 CsbD-like Abhydrolase_6 PF12697.7 KIY69566.1 - 1.5e-12 48.6 0.0 2.3e-12 48.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KIY69566.1 - 6.9e-08 32.4 0.6 2.3e-07 30.8 0.5 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIY69566.1 - 7.6e-05 22.1 0.1 0.001 18.4 0.1 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 KIY69566.1 - 0.017 14.2 0.0 0.025 13.6 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase zf-MYND PF01753.18 KIY69567.1 - 1.8e-09 37.5 20.0 4.5e-09 36.2 19.3 1.9 1 1 1 2 2 2 1 MYND finger zf-C6H2 PF15801.5 KIY69567.1 - 0.03 14.6 9.9 0.054 13.8 9.9 1.4 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-Mss51 PF13824.6 KIY69567.1 - 2.3 8.4 7.1 6 7.0 7.1 1.7 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.18 KIY69568.1 - 7.5e-10 38.7 15.6 3e-09 36.8 14.5 2.2 1 1 1 2 2 2 2 MYND finger zf-C6H2 PF15801.5 KIY69568.1 - 0.018 15.4 7.0 0.043 14.1 7.0 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Fungal_trans PF04082.18 KIY69570.1 - 3.9e-08 32.7 0.1 7.2e-08 31.8 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY69570.1 - 2.7e-07 30.6 11.3 5e-07 29.7 11.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GPI2 PF06432.11 KIY69575.1 - 1.3e-75 254.5 10.3 1.6e-75 254.2 10.3 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase CoA_binding_3 PF13727.6 KIY69575.1 - 1 9.4 6.8 0.18 11.8 2.5 1.9 2 0 0 2 2 2 0 CoA-binding domain Transketolase_N PF00456.21 KIY69576.1 - 2e-151 503.7 0.0 2.6e-151 503.3 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 KIY69576.1 - 1e-43 149.1 0.0 2.2e-43 148.0 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KIY69576.1 - 9.9e-14 51.3 0.0 2.1e-13 50.3 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 KIY69576.1 - 6.3e-06 25.6 0.2 1.8e-05 24.1 0.3 1.7 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 KIY69576.1 - 7.4e-05 22.6 0.4 0.0006 19.6 0.4 2.5 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.20 KIY69576.1 - 0.0054 15.7 0.0 0.0095 14.9 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component zf-C2HC_2 PF13913.6 KIY69577.1 - 0.13 12.2 2.7 0.3 11.0 2.7 1.7 1 0 0 1 1 1 0 zinc-finger of a C2HC-type zf-C2H2_4 PF13894.6 KIY69577.1 - 2 9.5 7.9 4.8 8.3 1.0 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger RNase_T PF00929.24 KIY69578.1 - 3.1e-11 44.1 0.0 4.7e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 KIY69578.1 - 0.13 11.9 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 3'-5' exonuclease Cmc1 PF08583.10 KIY69579.1 - 1.2e-14 54.0 3.1 1.6e-14 53.7 3.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like NDUF_B7 PF05676.13 KIY69579.1 - 0.0031 17.2 0.7 0.0052 16.5 0.7 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) NIP_1 PF08995.10 KIY69579.1 - 0.0083 16.5 0.0 0.011 16.1 0.0 1.1 1 0 0 1 1 1 1 Necrosis inducing protein-1 DUF928 PF06051.12 KIY69579.1 - 0.035 14.0 0.1 0.037 13.9 0.1 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF928) Pannexin_like PF12534.8 KIY69579.1 - 0.067 12.3 1.1 0.075 12.1 1.1 1.0 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 GCK PF07802.11 KIY69579.1 - 0.084 13.3 2.7 0.11 12.9 2.4 1.5 1 1 0 1 1 1 0 GCK domain DUF3128 PF11326.8 KIY69579.1 - 2.4 8.6 7.8 9.6 6.7 7.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) Glyco_hydro_31 PF01055.26 KIY69580.1 - 8.9e-117 391.0 1.0 1.1e-116 390.6 1.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KIY69580.1 - 1.1e-16 60.9 0.2 2.2e-16 59.9 0.2 1.6 1 0 0 1 1 1 1 Galactose mutarotase-like V_ATPase_I PF01496.19 KIY69581.1 - 0.093 10.6 1.0 0.12 10.2 1.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family UQ_con PF00179.26 KIY69582.1 - 2.4e-48 163.3 0.0 2.8e-48 163.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme HA2 PF04408.23 KIY69583.1 - 1e-21 77.3 0.0 1e-21 77.3 0.0 3.7 4 0 0 4 4 4 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KIY69583.1 - 2.4e-14 53.4 0.0 7.3e-14 51.9 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KIY69583.1 - 9.5e-14 51.7 0.0 2.6e-13 50.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KIY69583.1 - 9.6e-08 32.0 0.0 2.9e-07 30.4 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KIY69583.1 - 4.4e-05 23.8 0.5 0.00018 21.8 0.5 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KIY69583.1 - 0.00084 19.7 0.0 0.0021 18.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 KIY69583.1 - 0.001 18.4 0.0 0.002 17.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 KIY69583.1 - 0.0021 17.8 0.0 0.0056 16.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KIY69583.1 - 0.02 14.0 0.0 0.041 12.9 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein ATPase PF06745.13 KIY69583.1 - 0.032 13.6 0.1 0.065 12.6 0.1 1.4 1 0 0 1 1 1 0 KaiC ABC_tran PF00005.27 KIY69583.1 - 0.046 14.2 0.1 0.43 11.1 0.0 2.7 2 0 0 2 2 2 0 ABC transporter PhoH PF02562.16 KIY69583.1 - 0.058 12.8 0.0 0.19 11.2 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein AAA_25 PF13481.6 KIY69583.1 - 0.09 12.3 0.0 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KIY69583.1 - 0.11 12.5 0.1 0.82 9.7 0.1 2.3 1 1 0 1 1 1 0 AAA domain Cyclin_N PF00134.23 KIY69586.1 - 2.3e-08 33.8 0.0 4.4e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Tup_N PF08581.10 KIY69586.1 - 0.051 13.9 0.4 0.25 11.7 0.0 2.0 2 0 0 2 2 2 0 Tup N-terminal Snf7 PF03357.21 KIY69587.1 - 4.5e-39 133.8 22.3 6e-39 133.4 20.0 1.9 2 0 0 2 2 2 1 Snf7 PAC1 PF16094.5 KIY69587.1 - 0.31 10.2 2.2 0.18 10.9 0.3 1.4 2 0 0 2 2 2 0 Proteasome assembly chaperone 4 YlqD PF11068.8 KIY69587.1 - 0.52 10.7 15.3 1.9 8.8 6.3 2.2 1 1 1 2 2 2 0 YlqD protein Remorin_C PF03763.13 KIY69587.1 - 9.3 6.2 13.4 0.58 10.1 7.2 2.1 1 1 1 2 2 2 0 Remorin, C-terminal region SKG6 PF08693.10 KIY69588.1 - 0.08 12.4 0.4 0.15 11.5 0.4 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Beta-APP PF03494.13 KIY69588.1 - 1 9.2 7.4 2.3 8.2 7.4 1.6 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) Sec20 PF03908.13 KIY69589.1 - 0.28 11.1 1.1 0.49 10.4 0.1 1.9 2 0 0 2 2 2 0 Sec20 Pyridoxal_deC PF00282.19 KIY69590.1 - 9.5e-64 215.4 0.0 1.2e-63 215.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KIY69590.1 - 6.1e-05 22.1 0.0 0.00011 21.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V OKR_DC_1 PF01276.20 KIY69590.1 - 0.07 11.8 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain PAP2 PF01569.21 KIY69591.1 - 1.8e-23 82.8 1.7 1.8e-23 82.8 1.7 1.6 2 0 0 2 2 2 1 PAP2 superfamily DUF2530 PF10745.9 KIY69591.1 - 0.0077 16.4 1.7 0.76 10.1 0.1 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF2530) Trns_repr_metal PF02583.17 KIY69594.1 - 0.43 11.0 5.8 0.6 10.5 0.1 3.4 2 2 1 3 3 3 0 Metal-sensitive transcriptional repressor RNA_pol_Rpb2_6 PF00562.28 KIY69596.1 - 7.5e-123 410.4 0.0 1e-122 410.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KIY69596.1 - 3.1e-55 186.9 0.0 5.3e-55 186.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 KIY69596.1 - 1.3e-28 99.2 0.1 3.1e-28 98.0 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 KIY69596.1 - 2.2e-25 89.4 0.0 1.8e-24 86.4 0.0 2.3 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 KIY69596.1 - 2.5e-25 88.5 1.4 9.3e-25 86.7 0.6 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 KIY69596.1 - 1e-19 70.5 0.0 2.2e-19 69.4 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 KIY69596.1 - 6.3e-11 42.7 0.2 1.7e-10 41.3 0.2 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 zf-AN1 PF01428.16 KIY69598.1 - 3.3e-14 52.8 24.7 5.3e-08 32.9 10.1 2.6 2 1 0 2 2 2 2 AN1-like Zinc finger Herpes_pp85 PF04637.12 KIY69598.1 - 0.87 7.9 2.7 1.4 7.2 2.7 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Nop PF01798.18 KIY69599.1 - 7.9e-86 287.3 0.0 7.9e-86 287.3 0.0 2.0 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 KIY69599.1 - 1e-20 73.8 2.1 1e-20 73.8 2.1 2.7 2 0 0 2 2 2 1 NOP5NT (NUC127) domain Glyco_hydro_43 PF04616.14 KIY69600.1 - 6.4e-21 74.9 3.2 6.4e-21 74.9 3.2 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 43 CBM_35 PF16990.5 KIY69600.1 - 2.8e-06 27.6 2.1 1.4e-05 25.3 1.6 2.1 2 0 0 2 2 2 1 Carbohydrate binding module (family 35) DAGK_cat PF00781.24 KIY69601.1 - 8.9e-16 57.7 0.0 1.5e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Tmemb_170 PF10190.9 KIY69603.1 - 1.6e-08 34.8 7.7 3.4e-06 27.4 2.8 2.0 2 0 0 2 2 2 2 Putative transmembrane protein 170 Nop PF01798.18 KIY69604.1 - 6.5e-85 284.3 0.2 1.4e-84 283.2 0.2 1.5 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 KIY69604.1 - 6.2e-20 71.3 0.1 2.6e-19 69.4 0.1 2.2 1 0 0 1 1 1 1 NOP5NT (NUC127) domain U1snRNP70_N PF12220.8 KIY69604.1 - 4.5 8.0 13.1 15 6.3 3.3 2.9 3 0 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF2264 PF10022.9 KIY69605.1 - 7e-143 476.0 0.1 8.6e-143 475.7 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) Glyco_transf_4 PF13439.6 KIY69606.1 - 4.4e-21 75.6 0.3 6.7e-21 75.0 0.3 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 KIY69606.1 - 2.1e-17 63.2 0.0 1.8e-16 60.1 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KIY69606.1 - 6.3e-11 43.0 0.0 2.6e-10 41.0 0.1 1.8 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.6 KIY69606.1 - 6.1e-05 23.5 0.0 0.00081 19.8 0.0 2.5 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KIY69606.1 - 0.021 15.2 0.0 0.06 13.7 0.0 1.9 1 1 0 1 1 1 0 Glycosyl transferases group 1 COesterase PF00135.28 KIY69607.1 - 1.7e-87 294.5 0.0 2e-87 294.2 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KIY69607.1 - 4e-06 26.8 0.0 5.8e-05 23.0 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Torus PF16131.5 KIY69609.1 - 6.9e-40 136.1 1.0 1.1e-39 135.4 1.0 1.3 1 0 0 1 1 1 1 Torus domain Nup35_RRM_2 PF14605.6 KIY69609.1 - 2.1e-05 24.4 0.0 4e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_1 PF00076.22 KIY69609.1 - 0.016 15.0 0.1 0.042 13.7 0.1 1.8 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_4 PF18044.1 KIY69609.1 - 0.017 14.9 4.9 0.032 14.0 4.9 1.4 1 0 0 1 1 1 0 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KIY69609.1 - 0.08 13.0 5.3 0.14 12.2 5.3 1.4 1 0 0 1 1 1 0 Zinc finger domain zf-CCCH PF00642.24 KIY69609.1 - 0.28 11.1 6.3 0.55 10.2 6.3 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PhoD PF09423.10 KIY69610.1 - 8.6e-37 126.9 0.1 1.9e-36 125.8 0.1 1.5 1 1 0 1 1 1 1 PhoD-like phosphatase UPF0669 PF17065.5 KIY69611.1 - 0.14 11.9 0.0 0.22 11.3 0.0 1.2 1 0 0 1 1 1 0 Putative cytokine, C6ORF120 UPF0669 PF17065.5 KIY69612.1 - 0.12 12.1 0.0 0.52 10.0 0.0 1.9 2 0 0 2 2 2 0 Putative cytokine, C6ORF120 AAA PF00004.29 KIY69613.1 - 2.5e-60 202.7 0.0 5.4e-44 149.8 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KIY69613.1 - 6.4e-09 36.4 0.0 0.0076 16.6 0.0 3.8 3 0 0 3 3 3 2 AAA ATPase domain AAA_5 PF07728.14 KIY69613.1 - 1.8e-07 31.2 0.1 0.023 14.7 0.0 3.0 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KIY69613.1 - 7e-07 29.8 0.0 0.051 14.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_lid_3 PF17862.1 KIY69613.1 - 1.9e-05 24.4 7.4 0.03 14.1 0.5 2.7 2 0 0 2 2 2 2 AAA+ lid domain AAA_22 PF13401.6 KIY69613.1 - 4.1e-05 23.9 0.1 0.0086 16.4 0.0 3.1 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 KIY69613.1 - 0.00088 19.1 0.0 0.0071 16.1 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 KIY69613.1 - 0.00099 19.1 0.2 0.71 9.9 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 KIY69613.1 - 0.0014 19.0 0.0 0.07 13.5 0.0 2.5 2 0 0 2 2 2 1 RNA helicase ATPase PF06745.13 KIY69613.1 - 0.0016 17.8 0.2 0.0036 16.7 0.0 1.6 2 0 0 2 2 1 1 KaiC AAA_2 PF07724.14 KIY69613.1 - 0.002 18.3 0.0 0.022 14.9 0.0 2.6 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_6 PF12774.7 KIY69613.1 - 0.0027 16.8 0.0 0.28 10.1 0.0 2.2 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region AAA_14 PF13173.6 KIY69613.1 - 0.003 17.6 0.0 1.1 9.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 KIY69613.1 - 0.0058 16.6 0.0 0.75 9.7 0.0 2.3 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_25 PF13481.6 KIY69613.1 - 0.0088 15.6 0.1 0.067 12.8 0.1 2.3 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.13 KIY69613.1 - 0.012 14.8 0.0 1.5 7.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 KIY69613.1 - 0.012 15.3 0.0 1.4 8.6 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain Mg_chelatase PF01078.21 KIY69613.1 - 0.012 15.0 0.3 0.083 12.3 0.1 2.3 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KIY69613.1 - 0.017 15.0 0.0 0.77 9.6 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KIY69613.1 - 0.018 14.6 0.0 0.12 11.8 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region TIP49 PF06068.13 KIY69613.1 - 0.024 13.9 0.0 0.065 12.4 0.0 1.7 1 0 0 1 1 1 0 TIP49 P-loop domain Parvo_NS1 PF01057.17 KIY69613.1 - 0.025 13.7 0.0 0.042 12.9 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 IstB_IS21 PF01695.17 KIY69613.1 - 0.028 14.2 0.0 0.057 13.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Vps4_C PF09336.10 KIY69613.1 - 0.032 14.2 0.0 0.15 12.1 0.0 2.1 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain AAA_33 PF13671.6 KIY69613.1 - 0.064 13.4 0.0 0.89 9.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KIY69613.1 - 0.072 12.8 0.1 0.18 11.5 0.0 1.6 2 0 0 2 2 1 0 AAA domain NB-ARC PF00931.22 KIY69613.1 - 0.079 12.1 0.0 14 4.8 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_28 PF13521.6 KIY69613.1 - 0.088 13.1 0.0 1.2 9.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 KIY69613.1 - 0.14 12.6 0.0 6 7.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KIY69613.1 - 0.17 11.2 0.0 21 4.3 0.0 2.8 3 0 0 3 3 3 0 Zeta toxin Pkinase PF00069.25 KIY69614.1 - 1.1e-60 205.2 0.0 1.5e-60 204.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY69614.1 - 1.5e-32 112.9 0.1 2.2e-32 112.4 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 KIY69614.1 - 9.8e-11 41.9 0.0 1.9e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KIY69614.1 - 2.8e-06 27.6 0.0 7.1e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Kdo PF06293.14 KIY69614.1 - 3e-05 23.5 0.0 4.8e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIY69614.1 - 0.00054 20.0 1.0 0.074 13.0 0.0 2.9 3 1 0 4 4 4 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KIY69614.1 - 0.00072 18.4 0.0 0.0011 17.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KIY69614.1 - 0.0023 17.3 0.0 0.0032 16.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KIY69614.1 - 0.11 12.1 0.2 0.21 11.2 0.2 1.4 1 0 0 1 1 1 0 RIO1 family CN_hydrolase PF00795.22 KIY69615.1 - 2e-56 191.3 0.0 2.2e-56 191.1 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Actin PF00022.19 KIY69616.1 - 2e-147 491.1 0.0 1.2e-146 488.5 0.0 1.8 1 1 0 1 1 1 1 Actin Methyltransf_29 PF03141.16 KIY69616.1 - 0.063 11.8 0.0 0.11 11.0 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Mis14 PF08641.12 KIY69617.1 - 9e-05 22.8 1.5 0.00019 21.7 1.5 1.7 1 1 0 1 1 1 1 Kinetochore protein Mis14 like MAJIN PF15077.6 KIY69617.1 - 0.061 13.1 0.1 0.075 12.8 0.1 1.3 1 0 0 1 1 1 0 Membrane-anchored junction protein F-box-like PF12937.7 KIY69618.1 - 4.7e-10 39.2 0.1 1.3e-09 37.8 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KIY69619.1 - 2.3e-09 37.0 0.1 6.6e-09 35.5 0.1 1.9 1 0 0 1 1 1 1 F-box-like Thioredoxin PF00085.20 KIY69619.1 - 0.012 15.5 0.0 0.027 14.4 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin Gar1 PF04410.14 KIY69622.1 - 1.4e-34 119.1 0.0 1.5e-34 119.0 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region BamHI PF02923.15 KIY69622.1 - 0.058 13.1 0.0 0.069 12.9 0.0 1.1 1 0 0 1 1 1 0 Restriction endonuclease BamHI Pilin PF00114.19 KIY69623.1 - 0.17 12.8 1.2 0.42 11.6 0.1 2.0 1 1 1 2 2 2 0 Pilin (bacterial filament) Sel1 PF08238.12 KIY69624.1 - 9.2e-50 166.0 23.6 3.5e-09 37.1 0.0 7.7 8 0 0 8 8 8 7 Sel1 repeat ANAPC3 PF12895.7 KIY69624.1 - 1.7 8.9 7.9 0.26 11.5 1.1 3.1 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 PGK PF00162.19 KIY69625.1 - 1.4e-145 485.0 0.2 1.6e-145 484.9 0.2 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase DUF4061 PF13270.6 KIY69626.1 - 0.65 10.3 4.1 1.2 9.6 4.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4061) Atg14 PF10186.9 KIY69626.1 - 6.7 5.7 10.1 9.3 5.2 10.1 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 2OG-FeII_Oxy_3 PF13640.6 KIY69627.1 - 1e-10 42.4 0.0 2.1e-10 41.4 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Mpp10 PF04006.12 KIY69627.1 - 0.11 10.9 20.9 0.16 10.4 20.9 1.1 1 0 0 1 1 1 0 Mpp10 protein PPP4R2 PF09184.11 KIY69627.1 - 0.23 11.0 16.4 0.33 10.5 16.4 1.2 1 0 0 1 1 1 0 PPP4R2 Presenilin PF01080.17 KIY69627.1 - 0.49 9.1 3.6 0.59 8.8 3.6 1.1 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 KIY69627.1 - 0.63 8.3 13.2 0.82 7.9 13.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Myc_N PF01056.18 KIY69627.1 - 0.91 9.3 9.2 1.5 8.6 9.2 1.3 1 0 0 1 1 1 0 Myc amino-terminal region Nop14 PF04147.12 KIY69627.1 - 1.2 7.2 23.8 1.6 6.8 23.8 1.1 1 0 0 1 1 1 0 Nop14-like family SAPS PF04499.15 KIY69627.1 - 1.5 7.5 4.9 1.9 7.1 4.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein BUD22 PF09073.10 KIY69627.1 - 1.6 8.0 19.9 2.3 7.5 19.9 1.1 1 0 0 1 1 1 0 BUD22 SpoIIIAH PF12685.7 KIY69627.1 - 1.8 8.3 10.2 2.9 7.7 10.2 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein SDA1 PF05285.12 KIY69627.1 - 2.3 7.5 22.6 3.4 7.0 22.6 1.2 1 0 0 1 1 1 0 SDA1 RR_TM4-6 PF06459.12 KIY69627.1 - 6.9 6.4 11.7 11 5.8 11.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SDA1 PF05285.12 KIY69629.1 - 8.6e-87 291.8 46.0 5.3e-46 157.6 12.2 3.1 2 1 1 3 3 3 3 SDA1 NUC130_3NT PF08158.12 KIY69629.1 - 3.5e-25 88.1 0.5 7.8e-24 83.8 0.0 2.9 3 0 0 3 3 3 1 NUC130/3NT domain Menin PF05053.13 KIY69629.1 - 1.2 7.4 10.4 1.9 6.7 9.3 1.8 2 0 0 2 2 2 0 Menin YlqD PF11068.8 KIY69629.1 - 2.5 8.5 8.3 0.89 9.9 4.3 2.2 2 0 0 2 2 2 0 YlqD protein EMC3_TMCO1 PF01956.16 KIY69629.1 - 4 7.1 5.0 4.6 6.9 0.3 2.5 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like DUF1043 PF06295.12 KIY69629.1 - 7.1 6.6 8.6 14 5.7 6.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) zf-MYND PF01753.18 KIY69630.1 - 1.8e-08 34.3 9.1 4.1e-08 33.2 9.1 1.6 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.18 KIY69631.1 - 3.5e-08 33.4 9.7 3.5e-08 33.4 9.7 1.8 2 0 0 2 2 2 1 MYND finger DUF3198 PF11433.8 KIY69631.1 - 0.14 12.1 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3198) TP2 PF01254.18 KIY69631.1 - 0.16 12.6 3.4 0.33 11.6 3.4 1.4 1 0 0 1 1 1 0 Nuclear transition protein 2 PWI PF01480.17 KIY69632.1 - 4.1e-10 39.8 0.0 7.2e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 PWI domain RRM_1 PF00076.22 KIY69632.1 - 5.5e-06 26.1 0.0 0.011 15.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.24 KIY69632.1 - 5.6e-06 26.1 6.6 9.4e-06 25.4 6.6 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_3 PF08777.11 KIY69632.1 - 9.5e-05 22.4 0.1 0.0088 16.1 0.0 2.6 2 0 0 2 2 2 1 RNA binding motif zf_CCCH_4 PF18345.1 KIY69632.1 - 0.0048 16.9 8.9 0.0081 16.2 8.9 1.4 1 0 0 1 1 1 1 Zinc finger domain Limkain-b1 PF11608.8 KIY69632.1 - 0.1 12.7 0.0 5.3 7.2 0.0 2.5 2 0 0 2 2 2 0 Limkain b1 PRKG1_interact PF15898.5 KIY69632.1 - 1.2 10.0 4.6 2.6 9.0 4.6 1.5 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain ResIII PF04851.15 KIY69633.1 - 7.6e-21 74.9 0.0 1.5e-20 73.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KIY69633.1 - 6.7e-20 71.5 0.0 1.5e-19 70.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KIY69633.1 - 9.4e-19 67.8 0.0 4.7e-17 62.3 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Use1 PF09753.9 KIY69635.1 - 0.0019 18.0 0.0 0.0021 17.8 0.0 1.1 1 0 0 1 1 1 1 Membrane fusion protein Use1 PTH2 PF01981.16 KIY69636.1 - 3.2e-42 143.5 0.4 4.8e-42 143.0 0.4 1.3 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Oxidored_q2 PF00420.24 KIY69637.1 - 9.2 6.0 10.3 2 8.1 0.4 2.9 2 1 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Sgf11 PF08209.11 KIY69638.1 - 3.8e-09 35.9 0.3 3.8e-09 35.9 0.3 1.8 2 0 0 2 2 2 1 Sgf11 (transcriptional regulation protein) zf-Di19 PF05605.12 KIY69638.1 - 0.018 15.3 2.5 0.88 9.9 0.3 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding SWIRM-assoc_2 PF16496.5 KIY69638.1 - 4.5 6.0 8.3 5.7 5.7 8.3 1.1 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal Clr2_transil PF16761.5 KIY69639.1 - 5.2e-21 75.3 0.1 1.1e-20 74.2 0.1 1.6 1 0 0 1 1 1 1 Transcription-silencing protein, cryptic loci regulator Clr2 Clr2 PF10383.9 KIY69639.1 - 2.7e-13 50.9 0.0 7.5e-13 49.5 0.0 1.8 1 0 0 1 1 1 1 Transcription-silencing protein Clr2 Beta_elim_lyase PF01212.21 KIY69640.1 - 2e-70 237.4 0.0 2.7e-70 237.0 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase zf-met2 PF12907.7 KIY69641.1 - 5.8e-14 51.9 4.8 9e-14 51.3 4.8 1.3 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.14 KIY69641.1 - 2.7e-06 28.1 14.5 2.7e-06 28.1 14.5 1.4 2 0 0 2 2 2 1 4F5 protein family Lipocalin_2 PF08212.12 KIY69641.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.2 1 1 0 1 1 1 0 Lipocalin-like domain zf-Tim10_DDP PF02953.15 KIY69642.1 - 1.2e-17 63.3 1.0 1.4e-17 63.0 1.0 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Neuroparsin PF07327.11 KIY69642.1 - 0.023 15.2 1.1 4.5 7.8 0.7 2.1 1 1 1 2 2 2 0 Neuroparsin DUF2116 PF09889.9 KIY69642.1 - 0.15 12.0 0.1 0.15 12.0 0.1 1.4 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) WD40 PF00400.32 KIY69643.1 - 8.5e-07 29.6 29.1 0.28 12.1 0.0 9.8 11 1 1 12 12 12 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY69643.1 - 8.4e-06 26.0 0.0 0.1 12.9 0.0 4.5 5 0 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Lactonase PF10282.9 KIY69643.1 - 0.02 14.1 0.0 0.71 9.1 0.0 2.9 3 0 0 3 3 3 0 Lactonase, 7-bladed beta-propeller Mpv17_PMP22 PF04117.12 KIY69644.1 - 1.5e-23 82.8 0.6 2.9e-23 81.9 0.6 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family PTH2 PF01981.16 KIY69646.1 - 1.2e-27 96.5 0.0 1.8e-27 95.9 0.0 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 DEAD PF00270.29 KIY69647.1 - 2.6e-45 154.4 0.1 5.1e-45 153.4 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIY69647.1 - 1.6e-25 89.6 0.1 1.8e-24 86.2 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KIY69647.1 - 2.7e-17 62.7 0.5 2.7e-17 62.7 0.5 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KIY69647.1 - 0.00014 21.9 0.0 0.00032 20.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KIY69647.1 - 0.085 13.1 0.1 0.51 10.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain UPF0121 PF03661.13 KIY69648.1 - 6.4e-37 127.2 7.1 7.4e-37 127.0 7.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) CBS PF00571.28 KIY69650.1 - 1.3e-31 108.8 6.4 6.1e-09 36.2 0.0 5.1 5 0 0 5 5 5 4 CBS domain PB1 PF00564.24 KIY69650.1 - 9.2e-10 38.3 0.2 2.9e-09 36.7 0.2 1.9 1 1 0 1 1 1 1 PB1 domain Ribosomal_60s PF00428.19 KIY69650.1 - 0.54 10.9 7.3 2.9 8.5 0.7 3.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein GFO_IDH_MocA PF01408.22 KIY69651.1 - 9.1e-22 78.1 0.0 1.3e-21 77.7 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 KIY69651.1 - 0.0046 17.6 0.1 0.0085 16.7 0.1 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.24 KIY69651.1 - 0.031 14.7 0.0 0.052 14.0 0.0 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Abhydrolase_3 PF07859.13 KIY69652.1 - 9.3e-14 51.8 0.2 4.3e-13 49.6 0.2 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KIY69652.1 - 3.1e-08 33.0 0.1 4.6e-08 32.4 0.1 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.7 KIY69652.1 - 0.00032 21.4 0.1 0.0004 21.0 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KIY69652.1 - 0.00037 20.0 0.1 0.0011 18.5 0.1 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KIY69652.1 - 0.0072 15.6 0.0 0.0091 15.3 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 KIY69652.1 - 0.019 14.7 0.0 0.99 9.1 0.0 2.1 2 0 0 2 2 2 0 PGAP1-like protein DUF915 PF06028.11 KIY69652.1 - 0.087 12.1 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) DUF1749 PF08538.10 KIY69652.1 - 0.18 10.8 0.0 0.29 10.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Band_7 PF01145.25 KIY69653.1 - 1.9e-24 86.6 0.5 3.4e-24 85.8 0.5 1.4 1 1 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 KIY69653.1 - 0.00021 20.5 1.5 0.00026 20.2 1.5 1.1 1 0 0 1 1 1 1 SigmaW regulon antibacterial RRM_1 PF00076.22 KIY69654.1 - 2.7e-54 180.9 0.0 2.2e-19 69.0 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KIY69654.1 - 1.7e-08 34.1 0.0 0.00015 21.3 0.0 3.2 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KIY69654.1 - 1.4e-06 28.1 0.0 0.0003 20.6 0.0 3.1 3 0 0 3 3 3 1 Occluded RNA-recognition motif Cas_Cas2CT1978 PF09707.10 KIY69654.1 - 0.0067 16.5 0.0 4.8 7.3 0.0 2.5 2 0 0 2 2 2 2 CRISPR-associated protein (Cas_Cas2CT1978) RRM_7 PF16367.5 KIY69654.1 - 0.011 15.8 0.0 0.2 11.8 0.0 2.7 2 1 0 2 2 2 0 RNA recognition motif Nup35_RRM_2 PF14605.6 KIY69654.1 - 0.021 14.8 0.1 18 5.4 0.0 3.2 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif TMEM247 PF15444.6 KIY69655.1 - 0.42 10.6 1.7 0.48 10.4 1.7 1.1 1 0 0 1 1 1 0 Transmembrane protein 247 ATG16 PF08614.11 KIY69656.1 - 3.6e-48 164.5 22.4 3.6e-48 164.5 22.4 1.5 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) MPS2 PF17060.5 KIY69656.1 - 0.013 14.8 5.8 0.018 14.3 5.8 1.2 1 0 0 1 1 1 0 Monopolar spindle protein 2 DUF4407 PF14362.6 KIY69656.1 - 0.058 12.7 14.9 0.11 11.9 14.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) VanY PF02557.17 KIY69656.1 - 0.32 10.8 4.0 0.45 10.3 0.4 2.4 2 0 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase TMF_TATA_bd PF12325.8 KIY69656.1 - 0.44 10.8 22.8 0.052 13.8 11.7 3.0 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding Fez1 PF06818.15 KIY69656.1 - 0.73 10.3 17.9 0.73 10.2 8.6 2.3 1 1 1 2 2 2 0 Fez1 Atg14 PF10186.9 KIY69656.1 - 0.88 8.6 12.0 1.4 7.9 12.0 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 YabA PF06156.13 KIY69656.1 - 1.4 9.6 17.6 0.12 13.0 3.5 2.9 2 1 1 3 3 3 0 Initiation control protein YabA DUF1664 PF07889.12 KIY69656.1 - 1.9 8.6 7.9 2.6 8.1 1.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) FlgN PF05130.12 KIY69656.1 - 3.4 8.1 20.9 1.5 9.3 15.2 2.3 1 1 0 2 2 2 0 FlgN protein Fib_alpha PF08702.10 KIY69656.1 - 3.5 7.8 19.0 0.34 11.1 10.0 2.5 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family ERM PF00769.19 KIY69656.1 - 3.9 7.2 24.5 0.067 13.0 17.3 1.6 2 0 0 2 2 2 0 Ezrin/radixin/moesin family SOGA PF11365.8 KIY69656.1 - 4 8.6 15.5 0.97 10.6 5.3 3.0 2 1 1 3 3 3 0 Protein SOGA DUF3574 PF12098.8 KIY69656.1 - 5.3 6.9 7.1 2.7 7.8 0.2 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF3574) Ras PF00071.22 KIY69657.1 - 9.4e-58 194.4 0.2 1.1e-57 194.2 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIY69657.1 - 2.1e-32 111.8 0.0 3.6e-32 111.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIY69657.1 - 7.3e-14 51.6 0.0 9.2e-14 51.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KIY69657.1 - 1.1e-07 31.9 0.0 2.3e-07 30.9 0.0 1.5 1 1 1 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KIY69657.1 - 4.1e-07 29.6 0.0 5.2e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KIY69657.1 - 3.7e-06 26.6 0.0 0.00015 21.3 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KIY69657.1 - 5e-05 23.3 0.3 0.0045 16.9 0.1 2.3 1 1 0 2 2 2 1 RsgA GTPase ATP_bind_1 PF03029.17 KIY69657.1 - 0.0004 20.2 0.4 0.017 14.9 0.1 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 KIY69657.1 - 0.00063 19.5 0.1 0.15 11.8 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Septin PF00735.18 KIY69657.1 - 0.0011 18.3 0.3 0.046 13.0 0.0 2.3 2 1 0 2 2 2 1 Septin cobW PF02492.19 KIY69657.1 - 0.0015 18.1 0.0 0.0053 16.4 0.0 1.8 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain SRPRB PF09439.10 KIY69657.1 - 0.0065 15.9 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 KIY69657.1 - 0.0069 16.7 0.0 0.017 15.4 0.0 1.7 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 KIY69657.1 - 0.0084 16.5 0.1 0.016 15.6 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 KIY69657.1 - 0.014 15.4 0.1 0.043 13.8 0.1 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 KIY69657.1 - 0.017 14.9 0.0 0.034 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KIY69657.1 - 0.018 14.6 0.0 0.031 13.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 KIY69657.1 - 0.023 15.3 0.0 0.93 10.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KIY69657.1 - 0.049 13.5 0.7 0.091 12.7 0.0 1.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 KIY69657.1 - 0.05 13.5 0.1 0.09 12.7 0.0 1.5 2 0 0 2 2 2 0 NTPase Glyco_hydro_75 PF07335.11 KIY69657.1 - 0.065 13.5 0.0 0.11 12.7 0.0 1.5 1 1 0 1 1 1 0 Fungal chitosanase of glycosyl hydrolase group 75 NACHT PF05729.12 KIY69657.1 - 0.076 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 KIY69657.1 - 0.13 12.8 0.1 0.49 10.9 0.0 1.9 2 0 0 2 2 2 0 ABC transporter Glyco_transf_8 PF01501.20 KIY69658.1 - 3.3e-29 102.2 0.0 9.3e-29 100.7 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 8 Methyltransf_24 PF13578.6 KIY69658.1 - 7.6e-15 55.8 0.1 1.8e-14 54.6 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Glyco_transf_24 PF18404.1 KIY69658.1 - 0.00015 21.3 0.0 0.0002 20.8 0.0 1.3 1 0 0 1 1 1 1 Glucosyltransferase 24 Methyltransf_3 PF01596.17 KIY69658.1 - 0.0038 16.4 0.0 0.013 14.7 0.0 1.7 1 1 0 1 1 1 1 O-methyltransferase Epimerase PF01370.21 KIY69659.1 - 1.1e-38 133.1 0.0 1.6e-38 132.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KIY69659.1 - 1.3e-22 80.6 0.0 2.2e-22 79.9 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Glycos_transf_2 PF00535.26 KIY69659.1 - 1e-16 61.2 0.2 2.5e-16 60.0 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase family 2 3Beta_HSD PF01073.19 KIY69659.1 - 1.3e-12 47.3 0.0 2.1e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KIY69659.1 - 2.8e-09 37.1 0.0 5.5e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 KIY69659.1 - 1.7e-07 30.6 0.0 2.8e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KIY69659.1 - 6.7e-07 28.7 0.0 0.00023 20.4 0.2 3.4 3 1 0 3 3 3 1 Polysaccharide biosynthesis protein Glyco_tranf_2_3 PF13641.6 KIY69659.1 - 6.2e-05 23.0 0.1 0.00056 19.9 0.0 2.6 3 0 0 3 3 3 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 KIY69659.1 - 0.0001 22.3 0.0 0.00022 21.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_2 PF10111.9 KIY69659.1 - 0.002 17.6 0.0 0.0037 16.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 NmrA PF05368.13 KIY69659.1 - 0.0029 17.2 0.0 0.0054 16.3 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family TrkA_N PF02254.18 KIY69659.1 - 0.0045 17.2 0.0 0.012 15.8 0.0 1.8 1 0 0 1 1 1 1 TrkA-N domain adh_short PF00106.25 KIY69659.1 - 0.021 14.3 0.0 0.049 13.1 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase NAD_binding_4 PF07993.12 KIY69659.1 - 0.025 13.8 0.0 0.13 11.4 0.0 2.1 1 1 1 2 2 2 0 Male sterility protein Glyco_transf_21 PF13506.6 KIY69659.1 - 0.035 13.6 0.0 0.083 12.4 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 21 KR PF08659.10 KIY69659.1 - 0.097 12.6 0.1 0.26 11.2 0.1 1.7 1 0 0 1 1 1 0 KR domain DUF4523 PF15023.6 KIY69661.1 - 0.032 14.1 0.0 0.058 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4523) Tim17 PF02466.19 KIY69662.1 - 3.6e-14 53.1 0.3 6e-14 52.4 0.3 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family zf-C2H2 PF00096.26 KIY69663.1 - 1.8e-08 34.4 14.9 0.0015 18.9 0.6 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 KIY69663.1 - 2.2e-08 33.7 10.1 0.0089 15.8 0.3 3.5 3 0 0 3 3 3 3 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 KIY69663.1 - 4e-05 24.1 11.1 0.0028 18.3 0.4 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KIY69663.1 - 0.0094 16.3 15.2 0.065 13.7 0.2 4.6 5 0 0 5 5 5 2 Zinc-finger double domain GAGA PF09237.11 KIY69663.1 - 0.024 14.4 0.1 0.024 14.4 0.1 2.5 4 0 0 4 4 4 0 GAGA factor zf-Di19 PF05605.12 KIY69663.1 - 0.039 14.2 6.0 0.71 10.2 0.1 2.7 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf_C2H2_ZHX PF18387.1 KIY69663.1 - 0.32 10.7 7.4 4 7.2 0.2 3.1 1 1 2 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_2 PF12756.7 KIY69663.1 - 0.44 10.9 6.3 5.6 7.3 0.8 2.6 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) OrsD PF12013.8 KIY69663.1 - 0.59 10.6 9.1 8.1 6.9 0.2 3.2 2 1 1 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-BED PF02892.15 KIY69663.1 - 2.5 8.2 9.5 0.13 12.3 2.1 2.7 2 1 0 2 2 2 0 BED zinc finger Pkinase_Tyr PF07714.17 KIY69665.1 - 5.1e-38 130.8 0.0 6.5e-38 130.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIY69665.1 - 2.3e-31 109.1 0.0 3.2e-31 108.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 KIY69665.1 - 0.12 11.9 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Pkinase_Tyr PF07714.17 KIY69666.1 - 6.2e-27 94.5 0.0 8.2e-27 94.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIY69666.1 - 1.1e-25 90.6 0.0 1.5e-25 90.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinesin PF00225.23 KIY69667.1 - 7e-85 284.9 0.0 1e-84 284.3 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KIY69667.1 - 1.6e-17 63.8 0.0 2.7e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 Microtubule binding Caskin-tail PF16632.5 KIY69667.1 - 0.17 12.3 0.3 3 8.3 0.2 2.6 2 0 0 2 2 2 0 C-terminal region of Caskin zf-MYND PF01753.18 KIY69668.1 - 3.3e-08 33.5 12.0 6.7e-08 32.5 12.0 1.5 1 0 0 1 1 1 1 MYND finger BTB PF00651.31 KIY69670.1 - 9.2e-06 25.9 0.0 7.5e-05 22.9 0.0 2.2 2 0 0 2 2 2 1 BTB/POZ domain Ras PF00071.22 KIY69671.1 - 2.7e-51 173.4 0.1 3.1e-51 173.2 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIY69671.1 - 2.4e-18 66.5 0.0 4.3e-18 65.7 0.0 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 KIY69671.1 - 0.00022 20.8 0.0 0.00067 19.2 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Arf PF00025.21 KIY69671.1 - 0.00043 19.8 0.0 0.00051 19.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KIY69671.1 - 0.0017 18.3 0.0 0.1 12.5 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 KIY69671.1 - 0.016 14.7 0.1 1.1 8.7 0.0 2.8 1 1 2 3 3 3 0 Ferrous iron transport protein B MMR_HSR1 PF01926.23 KIY69671.1 - 0.063 13.4 0.0 0.22 11.6 0.0 1.9 1 1 1 2 2 2 0 50S ribosome-binding GTPase Yippee-Mis18 PF03226.14 KIY69674.1 - 9.6e-17 61.1 0.2 1.1e-16 61.0 0.2 1.0 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 KIY69674.1 - 0.012 15.9 0.4 0.017 15.4 0.4 1.3 1 1 0 1 1 1 0 C-terminal domain of RIG-I Peptidase_C48 PF02902.19 KIY69675.1 - 1.4e-42 146.0 1.4 1.9e-42 145.5 1.4 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Complex1_30kDa PF00329.19 KIY69676.1 - 3.7e-45 153.5 0.0 5.1e-45 153.0 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit BCAS2 PF05700.11 KIY69677.1 - 7.1e-63 212.0 11.0 7.9e-63 211.9 11.0 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) Mesd PF10185.9 KIY69677.1 - 0.0068 16.4 0.2 0.012 15.5 0.2 1.4 1 0 0 1 1 1 1 Chaperone for wingless signalling and trafficking of LDL receptor Spectrin PF00435.21 KIY69677.1 - 0.011 16.3 5.4 0.028 14.9 4.5 2.3 2 1 0 2 2 2 0 Spectrin repeat DUF4355 PF14265.6 KIY69677.1 - 0.028 14.7 1.5 0.049 13.9 0.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4355) DUF3037 PF11236.8 KIY69677.1 - 0.049 14.1 0.3 0.1 13.1 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3037) LRR_RI_capping PF18779.1 KIY69677.1 - 0.073 12.7 0.2 0.18 11.5 0.2 1.6 1 0 0 1 1 1 0 Capping Ribonuclease inhibitor Leucine Rich Repeat Lzipper-MIP1 PF14389.6 KIY69677.1 - 0.97 9.8 10.2 0.23 11.8 5.0 2.3 2 1 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 APG6_N PF17675.1 KIY69677.1 - 2.4 8.7 12.6 0.23 12.0 5.6 2.4 1 1 0 2 2 2 0 Apg6 coiled-coil region CLZ PF16526.5 KIY69677.1 - 5.1 7.5 10.7 0.19 12.1 2.9 2.7 3 1 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels bZIP_1 PF00170.21 KIY69677.1 - 5.2 7.2 8.1 25 5.1 3.1 3.3 2 1 1 3 3 3 0 bZIP transcription factor Atg14 PF10186.9 KIY69679.1 - 0.092 11.8 1.5 0.13 11.3 1.5 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 HIP1_clath_bdg PF16515.5 KIY69679.1 - 1.4 9.6 4.5 1.4 9.6 2.3 2.0 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 TIMELESS PF04821.14 KIY69680.1 - 2.4e-50 171.4 0.0 2.4e-50 171.4 0.0 2.8 3 0 0 3 3 3 1 Timeless protein TIMELESS_C PF05029.13 KIY69680.1 - 2.2e-07 30.4 6.5 2.2e-07 30.4 6.5 3.3 1 1 2 3 3 3 1 Timeless protein C terminal region PA26 PF04636.13 KIY69680.1 - 3.1 6.6 6.2 5.1 5.9 6.2 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF4228 PF14009.6 KIY69680.1 - 3.9 7.8 17.6 3 8.2 14.4 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4228) Pal1 PF08316.11 KIY69680.1 - 4.5 8.0 7.5 3.1 8.6 5.0 1.9 1 1 0 2 2 2 0 Pal1 cell morphology protein ATP-grasp_2 PF08442.10 KIY69681.1 - 5.6e-71 238.3 0.8 5.6e-71 238.3 0.8 1.7 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.19 KIY69681.1 - 7.3e-26 90.8 0.2 1.6e-25 89.7 0.2 1.6 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 KIY69681.1 - 7.3e-09 35.4 0.7 1.9e-08 34.0 0.1 1.9 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.19 KIY69681.1 - 0.00082 19.2 0.2 0.0034 17.2 0.0 2.0 2 1 1 3 3 3 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain DinB_2 PF12867.7 KIY69682.1 - 4e-05 24.1 0.3 5.4e-05 23.7 0.3 1.1 1 0 0 1 1 1 1 DinB superfamily EpmC PF04315.12 KIY69682.1 - 0.069 12.8 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Elongation factor P hydroxylase Pkinase PF00069.25 KIY69683.1 - 9.9e-31 107.1 0.0 3.6e-30 105.2 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY69683.1 - 2.9e-05 23.5 0.1 0.0035 16.7 0.1 2.8 1 1 0 1 1 1 1 Protein tyrosine kinase DUF3337 PF11816.8 KIY69684.1 - 1.2e-36 126.1 0.0 2e-36 125.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) WD40 PF00400.32 KIY69684.1 - 3.1e-17 62.6 16.6 0.0016 19.2 0.5 6.8 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY69684.1 - 0.01 16.1 0.0 1.9 8.8 0.0 3.1 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIY69684.1 - 0.011 14.7 0.0 0.12 11.3 0.0 2.2 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein RAWUL PF16207.5 KIY69684.1 - 0.014 16.1 0.0 0.028 15.1 0.0 1.5 1 0 0 1 1 1 0 RAWUL domain RING finger- and WD40-associated ubiquitin-like PALB2_WD40 PF16756.5 KIY69684.1 - 0.025 13.5 3.7 1.5 7.7 0.0 2.7 3 0 0 3 3 3 0 Partner and localizer of BRCA2 WD40 domain Nup160 PF11715.8 KIY69684.1 - 0.36 9.4 4.2 2.4 6.7 0.0 3.1 4 0 0 4 4 4 0 Nucleoporin Nup120/160 Caps_synth_CapC PF14102.6 KIY69685.1 - 0.69 10.4 7.0 7.8 7.0 0.8 2.2 2 0 0 2 2 2 0 Capsule biosynthesis CapC Hist_deacetyl PF00850.19 KIY69686.1 - 8.7e-86 288.2 0.0 1.1e-85 287.8 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain DUF1256 PF06866.11 KIY69686.1 - 0.016 14.6 0.0 0.029 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1256) NIL PF09383.10 KIY69686.1 - 0.047 13.6 0.0 0.087 12.7 0.0 1.4 1 0 0 1 1 1 0 NIL domain XPA_C PF05181.12 KIY69687.1 - 3.3e-23 81.4 1.4 6.1e-23 80.5 1.4 1.5 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.18 KIY69687.1 - 0.23 11.5 11.4 0.14 12.2 5.5 2.6 2 0 0 2 2 2 0 XPA protein N-terminal zf_UBZ PF18439.1 KIY69687.1 - 8 6.1 8.8 20 4.9 0.5 3.3 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger 4HBT_3 PF13622.6 KIY69688.1 - 2.3e-54 185.3 0.0 2.9e-54 185.0 0.0 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 KIY69688.1 - 5.3e-22 78.1 0.0 7.3e-17 61.4 0.0 3.2 2 1 1 3 3 3 2 Acyl-CoA thioesterase 4HBT PF03061.22 KIY69688.1 - 0.089 13.2 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 Thioesterase superfamily Nuclease_act PF08133.11 KIY69688.1 - 0.47 10.7 1.7 6.2 7.2 0.0 2.6 2 0 0 2 2 2 0 Anticodon nuclease activator family DnaJ PF00226.31 KIY69689.1 - 7.4e-20 70.8 0.0 4e-19 68.5 0.0 2.2 2 0 0 2 2 2 1 DnaJ domain SMN PF06003.12 KIY69689.1 - 0.11 11.8 6.3 0.33 10.2 1.2 2.2 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) DUF4337 PF14235.6 KIY69689.1 - 3.4 7.8 4.1 5.9 7.0 4.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) MFS_1 PF07690.16 KIY69690.1 - 2.1e-31 109.1 62.5 3.1e-29 102.0 31.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIY69690.1 - 3.2e-07 29.6 25.7 1.1e-06 27.8 4.2 2.7 2 1 1 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 KIY69690.1 - 5.5e-05 21.8 0.9 5.5e-05 21.8 0.9 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 KIY69690.1 - 0.014 14.3 0.9 0.014 14.3 0.9 2.7 2 1 0 2 2 2 0 MFS_1 like family Chalcone_2 PF16035.5 KIY69691.1 - 9.5e-28 97.4 0.8 1.7e-16 60.7 0.0 2.2 1 1 1 2 2 2 2 Chalcone isomerase like Chalcone_3 PF16036.5 KIY69691.1 - 0.027 14.6 0.0 0.048 13.8 0.0 1.5 1 1 0 1 1 1 0 Chalcone isomerase-like BLM10_mid PF16507.5 KIY69692.1 - 2.2e-178 594.2 0.0 5.4e-178 592.9 0.0 1.6 2 0 0 2 2 2 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 KIY69692.1 - 2.2e-31 107.6 0.5 4.8e-29 100.1 0.1 4.3 4 0 0 4 4 4 1 Domain of unknown function (DUF3437) HEAT PF02985.22 KIY69692.1 - 0.00011 22.1 3.3 0.0026 17.9 0.1 4.6 4 0 0 4 4 4 1 HEAT repeat HEAT_2 PF13646.6 KIY69692.1 - 0.00015 22.1 1.1 0.015 15.7 0.0 4.4 5 0 0 5 5 5 1 HEAT repeats Vac14_Fab1_bd PF12755.7 KIY69692.1 - 0.037 14.6 0.0 0.33 11.6 0.0 2.7 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region NopRA1 PF16201.5 KIY69692.1 - 0.094 12.3 4.5 0.43 10.1 0.0 4.0 5 0 0 5 5 5 0 Nucleolar pre-ribosomal-associated protein 1 RRN3 PF05327.11 KIY69692.1 - 0.1 11.1 0.1 0.25 9.8 0.1 1.6 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 HEAT_EZ PF13513.6 KIY69692.1 - 0.48 11.0 1.7 8.8 7.0 0.0 3.8 4 0 0 4 4 4 0 HEAT-like repeat zf-CCCH PF00642.24 KIY69693.1 - 2e-18 65.8 14.3 2.4e-10 40.0 3.0 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KIY69693.1 - 3.5e-09 36.4 13.6 1.2e-06 28.3 3.7 2.4 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 KIY69693.1 - 1.4e-07 31.1 11.5 0.00012 21.8 1.0 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger Torus PF16131.5 KIY69693.1 - 0.052 14.3 9.5 0.41 11.4 1.4 2.6 1 1 1 2 2 2 0 Torus domain zf-CCCH_2 PF14608.6 KIY69693.1 - 0.057 13.9 8.5 0.16 12.5 0.2 2.4 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Choline_kinase PF01633.20 KIY69694.1 - 5.6e-49 166.6 0.0 7.5e-49 166.2 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 KIY69694.1 - 2.4e-12 47.3 0.1 3.8e-12 46.7 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family ACT_7 PF13840.6 KIY69695.1 - 7.3e-20 70.5 0.0 2.6e-12 46.4 0.0 2.4 2 0 0 2 2 2 2 ACT domain ACT PF01842.25 KIY69695.1 - 0.021 14.6 0.1 1.6 8.6 0.0 3.0 3 0 0 3 3 3 0 ACT domain Alpha-amylase_C PF02806.18 KIY69696.1 - 1.4e-24 86.4 0.0 3.2e-24 85.2 0.0 1.7 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 KIY69696.1 - 6e-21 74.6 0.1 2.9e-20 72.4 0.0 2.1 2 0 0 2 2 2 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 KIY69696.1 - 2e-11 44.0 0.0 2.1e-09 37.4 0.1 2.3 1 1 1 2 2 2 2 Alpha amylase, catalytic domain CAP PF00188.26 KIY69700.1 - 8.8e-20 71.8 2.4 1.1e-19 71.5 2.4 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Prefoldin_2 PF01920.20 KIY69702.1 - 5.1e-22 77.8 2.3 6.6e-22 77.5 2.3 1.1 1 0 0 1 1 1 1 Prefoldin subunit Phage_Mu_Gam PF07352.12 KIY69702.1 - 2.5e-05 24.2 2.2 3.1e-05 23.9 2.2 1.2 1 0 0 1 1 1 1 Bacteriophage Mu Gam like protein DUF4924 PF16271.5 KIY69702.1 - 0.014 15.4 0.2 0.019 15.0 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4924) PqqD PF05402.12 KIY69702.1 - 0.051 13.9 0.1 0.54 10.6 0.0 2.1 2 0 0 2 2 2 0 Coenzyme PQQ synthesis protein D (PqqD) KORA PF16509.5 KIY69702.1 - 0.06 13.6 0.0 0.1 12.9 0.0 1.4 1 0 0 1 1 1 0 TrfB plasmid transcriptional repressor EF-hand_8 PF13833.6 KIY69702.1 - 0.11 12.3 0.0 0.43 10.5 0.0 2.0 1 1 1 2 2 2 0 EF-hand domain pair Fer4 PF00037.27 KIY69703.1 - 5.8e-14 51.2 17.5 1.9e-08 33.8 4.5 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 KIY69703.1 - 1.1e-12 48.4 9.4 1.7e-12 47.7 9.4 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 KIY69703.1 - 9.2e-11 42.5 8.7 2.2e-05 25.3 0.6 2.3 1 1 1 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 KIY69703.1 - 1.1e-09 38.3 32.2 4e-06 26.9 12.4 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_10 PF13237.6 KIY69703.1 - 1.1e-08 35.0 22.0 3e-06 27.2 12.5 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 KIY69703.1 - 1.2e-08 35.2 3.1 0.00019 21.8 0.2 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 KIY69703.1 - 1.4e-08 34.8 9.9 2.3e-08 34.1 9.9 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 KIY69703.1 - 4.5e-07 29.7 17.8 0.00042 20.3 5.4 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 KIY69703.1 - 1.2e-06 28.2 11.7 0.0025 17.8 1.7 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 KIY69703.1 - 6.6e-06 26.2 11.0 0.00032 21.0 1.9 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 KIY69703.1 - 0.00013 22.4 10.8 0.023 15.2 12.5 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_13 PF13370.6 KIY69703.1 - 0.0036 17.8 12.6 0.23 12.0 1.2 2.5 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I c-SKI_SMAD_bind PF08782.10 KIY69703.1 - 0.0092 16.2 5.7 0.63 10.3 0.4 2.4 1 1 1 2 2 2 2 c-SKI Smad4 binding domain Fer4_18 PF13746.6 KIY69703.1 - 0.041 14.1 9.1 0.67 10.2 1.1 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 KIY69703.1 - 0.24 12.4 16.3 0.37 11.8 4.1 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_22 PF17179.4 KIY69703.1 - 0.36 11.7 11.9 1.5 9.7 1.5 2.3 1 1 2 3 3 3 0 4Fe-4S dicluster domain EPF PF17181.4 KIY69703.1 - 0.6 10.2 5.3 0.43 10.6 0.5 2.2 2 0 0 2 2 2 0 Epidermal patterning factor proteins ETF_QO PF05187.13 KIY69703.1 - 0.77 9.9 7.1 3.3 7.9 0.8 2.3 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S BRE1 PF08647.11 KIY69704.1 - 0.067 13.3 3.3 0.11 12.6 3.3 1.3 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase bZIP_2 PF07716.15 KIY69704.1 - 0.44 10.7 3.2 0.6 10.2 1.9 1.9 1 1 0 1 1 1 0 Basic region leucine zipper GRIM-19 PF06212.12 KIY69705.1 - 1.7e-27 96.0 0.0 2e-27 95.8 0.0 1.0 1 0 0 1 1 1 1 GRIM-19 protein HMG_box PF00505.19 KIY69706.1 - 7.7e-13 48.7 19.3 6.5e-07 29.7 6.5 3.4 3 1 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.10 KIY69706.1 - 1.8e-12 47.7 13.0 7.4e-06 26.5 1.5 2.5 2 0 0 2 2 2 2 HMG-box domain T3SSipB PF16535.5 KIY69706.1 - 0.066 13.7 2.6 0.12 12.8 2.6 1.4 1 0 0 1 1 1 0 Type III cell invasion protein SipB Acetyltransf_10 PF13673.7 KIY69708.1 - 1e-10 41.6 0.0 1.3e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KIY69708.1 - 6.1e-05 23.4 0.0 8.2e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIY69708.1 - 0.00012 22.2 0.0 0.00017 21.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_5 PF13444.6 KIY69708.1 - 0.012 16.3 0.0 0.033 14.9 0.0 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF5313 PF17240.2 KIY69708.1 - 0.033 14.6 0.0 0.051 14.0 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5313) PPR_2 PF13041.6 KIY69709.1 - 5e-50 167.5 0.3 4.7e-08 33.1 0.0 11.6 6 2 5 11 11 11 10 PPR repeat family PPR_3 PF13812.6 KIY69709.1 - 1.2e-39 134.2 0.0 3.7e-10 39.7 0.0 8.7 6 2 3 9 9 9 6 Pentatricopeptide repeat domain PPR PF01535.20 KIY69709.1 - 1.5e-34 115.8 9.4 0.058 13.7 0.2 14.3 15 0 0 15 15 15 9 PPR repeat PPR_1 PF12854.7 KIY69709.1 - 3.5e-19 68.2 0.0 0.0058 16.3 0.0 8.9 10 0 0 10 10 10 5 PPR repeat PPR_long PF17177.4 KIY69709.1 - 3.8e-16 59.1 0.0 1.4e-07 31.1 0.0 5.4 4 1 1 6 6 6 3 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 KIY69709.1 - 6.3e-05 23.5 16.8 13 6.9 0.0 10.3 11 2 1 12 12 12 2 Tetratricopeptide repeat TPR_19 PF14559.6 KIY69709.1 - 0.0002 21.8 1.6 6.6 7.3 0.0 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_4 PF07721.14 KIY69709.1 - 0.037 14.6 15.5 24 5.9 0.1 7.1 7 0 0 7 7 7 0 Tetratricopeptide repeat ECSIT PF06239.11 KIY69709.1 - 0.11 11.6 0.0 1.5 7.9 0.0 2.5 1 1 1 2 2 2 0 Evolutionarily conserved signalling intermediate in Toll pathway ArfGap PF01412.18 KIY69710.1 - 6.2e-33 113.3 0.1 1.3e-32 112.3 0.1 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Velvet PF11754.8 KIY69711.1 - 1.1e-79 267.9 0.0 1.3e-79 267.7 0.0 1.0 1 0 0 1 1 1 1 Velvet factor Vac14_Fig4_bd PF11916.8 KIY69712.1 - 1.2e-78 262.8 7.2 1.9e-78 262.2 7.2 1.3 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 KIY69712.1 - 3.5e-28 98.0 0.5 6e-23 81.3 0.1 4.6 4 1 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 KIY69712.1 - 2.2e-09 36.8 0.1 0.03 14.6 0.0 5.8 5 0 0 5 5 5 2 HEAT repeat Cnd1 PF12717.7 KIY69712.1 - 0.00016 21.8 0.6 1.5 8.8 0.4 3.7 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 KIY69712.1 - 0.00085 18.9 0.1 6.7 6.2 0.0 3.5 3 1 0 3 3 3 1 CLASP N terminal HEAT_EZ PF13513.6 KIY69712.1 - 0.00098 19.6 3.3 8.5 7.0 0.0 5.6 5 2 2 7 7 7 2 HEAT-like repeat HEAT_2 PF13646.6 KIY69712.1 - 0.017 15.5 0.4 11 6.5 0.1 3.7 3 1 0 3 3 3 0 HEAT repeats RibD_C PF01872.17 KIY69713.1 - 8.4e-36 123.7 0.0 9.8e-36 123.5 0.0 1.0 1 0 0 1 1 1 1 RibD C-terminal domain SNARE PF05739.19 KIY69714.1 - 4.3e-09 36.2 0.3 6.6e-09 35.6 0.3 1.3 1 0 0 1 1 1 1 SNARE domain Fusion_gly PF00523.18 KIY69714.1 - 0.019 13.2 0.0 0.022 13.0 0.0 1.1 1 0 0 1 1 1 0 Fusion glycoprotein F0 Importin_rep_4 PF18808.1 KIY69714.1 - 0.11 12.8 0.3 0.29 11.4 0.1 1.7 1 1 1 2 2 2 0 Importin repeat Syndecan PF01034.20 KIY69714.1 - 0.39 10.7 2.9 0.75 9.7 2.7 1.6 2 0 0 2 2 2 0 Syndecan domain OppC_N PF12911.7 KIY69714.1 - 1.8 8.6 6.2 3.2 7.8 6.2 1.3 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Y_phosphatase3 PF13350.6 KIY69715.1 - 3e-62 210.6 0.0 3.5e-62 210.4 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 KIY69715.1 - 0.00044 19.9 0.0 0.00072 19.2 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 KIY69715.1 - 0.0028 17.2 0.0 0.0038 16.8 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KIY69715.1 - 0.013 15.6 0.0 0.039 14.1 0.0 1.8 1 1 0 1 1 1 0 Inositol hexakisphosphate DNA_mis_repair PF01119.19 KIY69716.1 - 3.3e-13 49.4 0.3 5.3e-11 42.2 0.3 2.4 1 1 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 KIY69716.1 - 1.4e-09 37.9 0.0 3.2e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KIY69716.1 - 7.3e-07 29.7 0.0 1.6e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.11 KIY69716.1 - 2.1e-05 24.3 0.1 0.00032 20.5 0.1 2.6 1 1 0 1 1 1 1 MutL C terminal dimerisation domain DUF202 PF02656.15 KIY69717.1 - 7.4e-19 68.0 1.1 7.4e-19 68.0 1.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF5504 PF17608.2 KIY69717.1 - 0.45 10.6 0.1 0.45 10.6 0.1 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5504) PsbN PF02468.15 KIY69717.1 - 9.9 6.1 6.8 6.4 6.7 0.5 2.4 2 0 0 2 2 2 0 Photosystem II reaction centre N protein (psbN) Carboxyl_trans PF01039.22 KIY69718.1 - 2.1e-127 425.7 0.0 2.7e-127 425.4 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain Las1 PF04031.13 KIY69720.1 - 8e-47 159.2 0.3 2.5e-46 157.6 0.2 1.9 2 0 0 2 2 2 1 Las1-like ABC_tran PF00005.27 KIY69721.1 - 3.4e-48 163.6 0.0 6.5e-30 104.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KIY69721.1 - 9.4e-40 137.0 21.0 5.5e-25 88.6 5.2 2.7 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 KIY69721.1 - 8e-10 38.5 0.9 0.0023 17.4 0.1 3.8 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KIY69721.1 - 1.8e-05 25.0 0.3 0.17 12.2 0.1 3.4 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KIY69721.1 - 0.00052 19.7 0.8 0.28 11.0 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.6 KIY69721.1 - 0.0062 16.1 0.0 2.3 7.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 KIY69721.1 - 0.011 14.8 0.0 2.3 7.2 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_16 PF13191.6 KIY69721.1 - 0.017 15.5 0.0 2.1 8.7 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_24 PF13479.6 KIY69721.1 - 0.027 14.2 0.0 0.091 12.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 KIY69721.1 - 0.034 14.3 0.0 0.089 12.9 0.0 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain ATPase PF06745.13 KIY69721.1 - 0.044 13.1 0.3 3.4 6.9 0.0 2.3 2 0 0 2 2 2 0 KaiC AAA_23 PF13476.6 KIY69721.1 - 0.053 14.0 0.2 10 6.5 0.1 2.3 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KIY69721.1 - 0.066 12.4 0.5 3.6 6.7 0.0 3.2 4 0 0 4 4 4 0 NB-ARC domain FtsK_SpoIIIE PF01580.18 KIY69721.1 - 0.081 12.3 0.4 14 5.0 0.0 2.5 3 0 0 3 3 3 0 FtsK/SpoIIIE family NACHT PF05729.12 KIY69721.1 - 0.15 12.0 0.8 12 5.8 0.1 2.6 2 0 0 2 2 2 0 NACHT domain MMR_HSR1 PF01926.23 KIY69721.1 - 0.15 12.2 0.0 5.3 7.2 0.0 2.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase cobW PF02492.19 KIY69721.1 - 0.57 9.7 2.3 1.1 8.8 0.3 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MFS_1 PF07690.16 KIY69722.1 - 6.5e-07 28.6 0.6 7.7e-07 28.3 0.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily PUCC PF03209.15 KIY69722.1 - 0.056 12.5 0.1 0.072 12.1 0.1 1.1 1 0 0 1 1 1 0 PUCC protein DUF2062 PF09835.9 KIY69722.1 - 0.078 12.8 0.1 0.1 12.5 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) Vps5 PF09325.10 KIY69724.1 - 4.7e-16 59.1 1.5 6.6e-16 58.6 1.5 1.1 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 KIY69724.1 - 2.2e-09 37.3 1.9 2.5e-09 37.1 0.0 2.1 3 0 0 3 3 3 1 PX domain DUF4570 PF15134.6 KIY69724.1 - 0.053 13.5 0.4 0.15 12.1 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) Baculo_F PF12259.8 KIY69724.1 - 0.073 11.6 1.7 0.1 11.1 1.7 1.1 1 0 0 1 1 1 0 Baculovirus F protein TruD PF01142.18 KIY69724.1 - 0.25 10.1 4.4 0.9 8.3 0.1 2.1 1 1 1 2 2 2 0 tRNA pseudouridine synthase D (TruD) Glyco_hydro_17 PF00332.18 KIY69725.1 - 1.2e-07 31.6 5.4 5.4e-06 26.2 0.8 2.5 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 ETRAMP PF09716.10 KIY69725.1 - 0.031 14.3 0.0 0.068 13.2 0.0 1.5 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF2613 PF11021.8 KIY69725.1 - 0.29 11.3 10.4 0.28 11.3 0.4 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2613) GTP_cyclohydro2 PF00925.20 KIY69726.1 - 8.1e-58 194.6 0.0 1.4e-57 193.9 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase II TMEM171 PF15471.6 KIY69727.1 - 0.027 13.5 0.0 0.033 13.2 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein family 171 TFR_dimer PF04253.15 KIY69729.1 - 6.4e-19 68.2 0.1 1.5e-17 63.8 0.0 2.6 3 0 0 3 3 3 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 KIY69729.1 - 8.6e-17 61.5 0.1 2e-15 57.0 0.1 2.2 1 1 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KIY69729.1 - 5.6e-10 39.1 0.0 1.8e-09 37.5 0.0 1.9 1 1 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 KIY69729.1 - 0.015 15.0 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 Nicastrin PF05450.15 KIY69729.1 - 0.063 12.7 0.8 0.098 12.1 0.0 1.6 2 0 0 2 2 2 0 Nicastrin Iso_dh PF00180.20 KIY69730.1 - 3.1e-121 404.8 0.0 3.7e-121 404.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase NOB1_Zn_bind PF08772.11 KIY69731.1 - 2.3e-29 101.3 0.6 4.1e-29 100.6 0.6 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like PIN_6 PF17146.4 KIY69731.1 - 2.7e-27 95.1 0.0 4.8e-27 94.3 0.0 1.4 1 0 0 1 1 1 1 PIN domain of ribonuclease zf-NADH-PPase PF09297.11 KIY69731.1 - 0.17 11.6 2.3 0.95 9.2 0.2 2.4 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain P21-Arc PF04062.14 KIY69732.1 - 5.5e-75 251.2 0.0 6.1e-75 251.0 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit Ion_trans PF00520.31 KIY69733.1 - 0.29 10.3 21.6 7.7 5.7 21.6 2.4 1 1 0 1 1 1 0 Ion transport protein Sld5 PF05916.11 KIY69734.1 - 1.1e-22 80.5 0.1 1.5e-22 80.1 0.1 1.2 1 0 0 1 1 1 1 GINS complex protein Haspin_kinase PF12330.8 KIY69735.1 - 8.4e-56 189.5 0.0 1.2e-55 189.0 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain DTHCT PF08070.11 KIY69735.1 - 4.7 8.0 17.8 0.38 11.5 7.5 3.3 2 1 1 3 3 3 0 DTHCT (NUC029) region SKN1 PF03935.15 KIY69736.1 - 1.2e-189 630.9 0.4 1.4e-189 630.7 0.4 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Spermine_synth PF01564.17 KIY69737.1 - 0.0062 16.0 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 Spermine/spermidine synthase domain DUF3602 PF12223.8 KIY69738.1 - 1.8e-22 79.7 31.4 6.2e-09 36.3 4.1 5.5 1 1 5 6 6 6 6 Protein of unknown function (DUF3602) UCH PF00443.29 KIY69739.1 - 2.5e-50 171.4 0.0 3.4e-50 171.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KIY69739.1 - 1.5e-22 80.6 0.0 1.8e-21 77.1 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 KIY69739.1 - 0.00021 20.8 1.8 1.3 8.4 1.7 3.1 2 1 0 2 2 2 2 Ubiquitin-specific peptidase-like, SUMO isopeptidase Peptidase_C12 PF01088.21 KIY69739.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase, family 1 zf_UBZ PF18439.1 KIY69739.1 - 1.2 8.8 3.3 0.34 10.5 0.3 1.7 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger APH PF01636.23 KIY69740.1 - 2.1e-12 47.5 0.0 7.8e-12 45.6 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family PTPA PF03095.15 KIY69740.1 - 0.024 14.1 0.0 0.04 13.4 0.0 1.2 1 0 0 1 1 1 0 Phosphotyrosyl phosphate activator (PTPA) protein PP2C PF00481.21 KIY69741.1 - 2e-31 109.6 0.0 7e-29 101.2 0.0 2.2 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KIY69741.1 - 0.0063 16.2 0.0 0.018 14.7 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C zf-C2H2 PF00096.26 KIY69743.1 - 0.0023 18.3 15.6 0.0034 17.7 0.7 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIY69743.1 - 0.0096 16.7 0.5 0.0096 16.7 0.5 3.8 4 1 0 4 4 4 1 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KIY69743.1 - 0.038 14.4 11.1 0.08 13.4 0.2 3.8 3 1 0 3 3 3 0 Zinc-finger double domain F-box PF00646.33 KIY69744.1 - 2.1e-07 30.6 3.2 4e-07 29.8 1.2 2.5 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KIY69744.1 - 0.00039 20.3 1.4 0.00092 19.1 1.4 1.7 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KIY69744.1 - 0.0082 16.0 0.6 0.0082 16.0 0.6 2.3 2 0 0 2 2 2 1 F-box BTB PF00651.31 KIY69745.1 - 6.1e-07 29.7 0.1 2.7e-06 27.6 0.1 1.9 2 0 0 2 2 2 1 BTB/POZ domain SOG2 PF10428.9 KIY69745.1 - 2.2 7.4 15.0 0.012 14.9 3.9 2.1 2 0 0 2 2 2 0 RAM signalling pathway protein DIOX_N PF14226.6 KIY69746.1 - 3.6e-28 98.7 0.2 5.6e-28 98.1 0.2 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KIY69746.1 - 4.5e-15 56.0 0.0 9.6e-15 54.9 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RCC1 PF00415.18 KIY69747.1 - 8.9e-60 199.1 17.1 6.4e-13 49.1 0.6 7.3 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KIY69747.1 - 1.8e-36 123.2 40.7 4.7e-08 32.6 0.6 8.2 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat YhfZ_C PF14503.6 KIY69747.1 - 0.034 13.7 0.0 0.053 13.1 0.0 1.2 1 0 0 1 1 1 0 YhfZ C-terminal domain Hira PF07569.11 KIY69747.1 - 0.049 13.4 0.0 14 5.3 0.0 2.8 3 0 0 3 3 3 0 TUP1-like enhancer of split PQQ_3 PF13570.6 KIY69747.1 - 0.055 14.0 1.6 9.8 6.8 0.0 3.8 3 0 0 3 3 3 0 PQQ-like domain SUKH-3 PF14433.6 KIY69747.1 - 0.071 13.6 0.5 1.1e+02 3.2 0.0 4.1 4 0 0 4 4 4 0 SUKH-3 immunity protein SPASM PF13186.6 KIY69747.1 - 0.094 13.2 0.0 15 6.2 0.0 3.1 3 0 0 3 3 3 0 Iron-sulfur cluster-binding domain Reg_prop PF07494.11 KIY69747.1 - 0.097 12.9 0.0 81 4.0 0.0 3.6 3 0 0 3 3 3 0 Two component regulator propeller Aldedh PF00171.22 KIY69748.1 - 2e-145 484.8 0.1 2.5e-145 484.5 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KIY69748.1 - 0.0028 16.8 0.0 0.0043 16.1 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) Snf7 PF03357.21 KIY69749.1 - 9.2e-47 158.8 14.3 1.1e-46 158.6 14.3 1.0 1 0 0 1 1 1 1 Snf7 DUF1319 PF07028.11 KIY69749.1 - 0.0067 16.6 1.2 0.023 14.9 0.2 2.3 1 1 0 2 2 2 1 Protein of unknown function (DUF1319) NPV_P10 PF05531.12 KIY69749.1 - 0.034 14.6 4.1 2.5 8.6 0.8 3.4 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Prefoldin_2 PF01920.20 KIY69749.1 - 0.053 13.5 12.5 0.64 10.0 0.0 3.4 2 1 0 3 3 3 0 Prefoldin subunit DUF5344 PF17279.2 KIY69749.1 - 0.072 13.7 9.2 0.35 11.5 4.7 3.1 1 1 1 2 2 2 0 Family of unknown function (DUF5344) ChaB PF06150.12 KIY69749.1 - 0.15 12.7 0.1 0.33 11.6 0.1 1.5 1 0 0 1 1 1 0 ChaB AAA_19 PF13245.6 KIY69749.1 - 0.24 11.7 2.5 0.53 10.6 2.5 1.5 1 1 0 1 1 1 0 AAA domain DUF2730 PF10805.8 KIY69749.1 - 1.6 8.9 6.8 1 9.5 0.3 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF2730) FlaC_arch PF05377.11 KIY69749.1 - 2.1 8.8 9.0 5.8 7.4 0.1 3.9 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) FapA PF03961.13 KIY69749.1 - 2.1 6.8 10.3 1.3 7.6 1.7 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A Uso1_p115_C PF04871.13 KIY69749.1 - 2.6 8.4 13.7 6 7.3 9.8 2.7 2 1 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Snf7 PF03357.21 KIY69750.1 - 4.8e-11 42.6 10.7 6.6e-11 42.1 10.7 1.2 1 0 0 1 1 1 1 Snf7 DMSP_lyase PF16867.5 KIY69750.1 - 0.0091 15.7 0.1 0.018 14.7 0.1 1.5 1 0 0 1 1 1 1 Dimethlysulfonioproprionate lyase BLOC1S3 PF15753.5 KIY69750.1 - 0.011 15.8 0.8 0.023 14.9 0.8 1.5 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 FAM117 PF15388.6 KIY69750.1 - 0.034 13.6 1.2 0.061 12.7 0.3 1.6 1 1 1 2 2 2 0 Protein Family FAM117 Ist1 PF03398.14 KIY69750.1 - 0.06 13.3 2.7 0.092 12.7 2.7 1.2 1 0 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway YlqD PF11068.8 KIY69750.1 - 0.069 13.5 6.6 0.52 10.7 1.5 2.3 1 1 0 2 2 2 0 YlqD protein Cnn_1N PF07989.11 KIY69750.1 - 3.1 8.0 7.2 14 5.9 2.8 3.0 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 Abhydrolase_1 PF00561.20 KIY69752.1 - 1.2e-41 143.1 0.0 3.5e-41 141.6 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 KIY69752.1 - 0.00012 21.9 0.1 0.0002 21.1 0.1 1.4 1 0 0 1 1 1 1 Putative esterase RFC1 PF08519.12 KIY69753.1 - 1.7e-55 187.5 0.0 1e-54 185.0 0.0 2.2 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.26 KIY69753.1 - 6e-12 45.8 0.0 1.7e-11 44.4 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 KIY69753.1 - 2.4e-10 40.9 0.0 6.7e-10 39.5 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KIY69753.1 - 1.7e-05 24.8 0.0 4.4e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain Sigma54_activat PF00158.26 KIY69753.1 - 0.0082 15.9 0.1 0.016 14.9 0.1 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_30 PF13604.6 KIY69753.1 - 0.016 15.0 0.1 0.016 15.0 0.1 2.3 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 KIY69753.1 - 0.016 15.6 1.4 0.033 14.6 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_assoc_2 PF16193.5 KIY69753.1 - 0.02 15.2 0.0 0.079 13.3 0.0 2.0 1 0 0 1 1 1 0 AAA C-terminal domain AAA_14 PF13173.6 KIY69753.1 - 0.036 14.1 0.0 0.096 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain DNA_pol3_delta PF06144.13 KIY69753.1 - 0.039 13.7 0.1 0.039 13.7 0.1 3.2 4 0 0 4 4 4 0 DNA polymerase III, delta subunit RuvB_N PF05496.12 KIY69753.1 - 0.1 12.4 0.0 0.3 10.8 0.0 1.8 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KIY69753.1 - 0.15 12.0 0.1 1.2 9.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 KIY69753.1 - 0.16 11.9 0.1 0.36 10.7 0.1 1.6 1 0 0 1 1 1 0 NTPase AAA_22 PF13401.6 KIY69753.1 - 0.18 12.1 0.3 0.96 9.7 0.3 2.2 1 1 0 1 1 1 0 AAA domain DUF2681 PF10883.8 KIY69753.1 - 0.68 10.4 4.5 3.5 8.1 4.5 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) AAA_28 PF13521.6 KIY69753.1 - 2.4 8.4 5.4 2.2 8.5 0.1 2.6 2 0 0 2 2 2 0 AAA domain PPR_2 PF13041.6 KIY69754.1 - 3.8e-38 129.5 12.6 4.8e-08 33.1 0.0 13.1 13 1 1 14 14 14 7 PPR repeat family PPR PF01535.20 KIY69754.1 - 2.4e-28 96.4 28.1 0.00016 21.7 0.1 14.2 17 0 0 17 17 16 6 PPR repeat PPR_1 PF12854.7 KIY69754.1 - 2.6e-16 59.0 12.7 0.0038 16.9 0.0 10.7 12 0 0 12 12 12 3 PPR repeat PPR_long PF17177.4 KIY69754.1 - 1.3e-14 54.1 3.7 9.1e-11 41.5 0.1 3.9 5 0 0 5 5 5 2 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 KIY69754.1 - 4.1e-14 52.4 5.0 8e-05 22.6 0.0 8.5 10 0 0 10 10 9 2 Pentatricopeptide repeat domain TPR_6 PF13174.6 KIY69754.1 - 0.0077 16.8 3.1 9.9 7.0 0.0 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 KIY69754.1 - 0.04 14.4 1.2 37 4.9 0.0 5.9 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_4 PF07721.14 KIY69754.1 - 0.079 13.6 0.7 14 6.6 0.2 4.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_MalT PF17874.1 KIY69754.1 - 0.11 11.9 1.5 1.8 7.8 0.1 3.3 3 1 0 3 3 3 0 MalT-like TPR region Nucleopor_Nup85 PF07575.13 KIY69754.1 - 0.18 10.3 0.0 1.2 7.6 0.0 2.1 2 0 0 2 2 2 0 Nup85 Nucleoporin TPR_16 PF13432.6 KIY69754.1 - 2 9.1 13.4 3.3 8.4 0.1 6.4 7 0 0 7 7 7 0 Tetratricopeptide repeat Syja_N PF02383.18 KIY69755.1 - 2.7e-71 240.5 0.0 3.9e-71 240.0 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain Erv26 PF04148.13 KIY69755.1 - 1.4e-64 217.7 4.9 2.3e-64 217.0 4.9 1.3 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 TMEM239 PF15841.5 KIY69755.1 - 0.024 14.6 1.0 0.069 13.1 1.0 1.7 1 0 0 1 1 1 0 Transmembrane protein 239 family Unstab_antitox PF09720.10 KIY69755.1 - 0.18 11.9 0.3 14 5.8 0.0 2.6 2 0 0 2 2 2 0 Putative addiction module component Erv26 PF04148.13 KIY69756.1 - 1.7e-64 217.5 4.6 2e-64 217.2 4.6 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 TMEM239 PF15841.5 KIY69756.1 - 0.013 15.4 2.5 0.013 15.4 2.5 2.4 2 1 1 3 3 3 0 Transmembrane protein 239 family DUF2909 PF11137.8 KIY69756.1 - 0.051 13.5 0.1 0.12 12.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2909) WD40 PF00400.32 KIY69757.1 - 4.2e-22 78.0 7.3 3.6e-07 30.8 0.8 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY69757.1 - 2.4e-09 37.4 0.1 0.003 17.8 0.0 4.3 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Iso_dh PF00180.20 KIY69758.1 - 2.8e-98 329.3 0.0 3.2e-98 329.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase BOFC_N PF08977.10 KIY69758.1 - 0.12 12.4 0.0 0.71 9.9 0.0 2.1 2 0 0 2 2 2 0 Bypass of Forespore C, N terminal RNA_pol_I_TF PF04090.12 KIY69760.1 - 1e-07 31.6 0.4 4.7e-06 26.2 0.0 2.1 1 1 1 2 2 2 2 RNA polymerase I specific initiation factor DUF5102 PF17104.5 KIY69761.1 - 2e-71 241.4 0.0 2.6e-71 241.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF5102) Gp49 PF05973.14 KIY69761.1 - 0.21 11.8 0.0 0.34 11.1 0.0 1.3 1 0 0 1 1 1 0 Phage derived protein Gp49-like (DUF891) Dioxygenase_C PF00775.21 KIY69763.1 - 3.8e-07 29.7 0.0 7.4e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Dioxygenase GATA PF00320.27 KIY69765.1 - 1.1e-25 88.9 20.4 2e-15 56.1 4.1 2.6 2 0 0 2 2 2 2 GATA zinc finger DUF1752 PF08550.10 KIY69765.1 - 1.2e-11 44.2 0.7 2.6e-11 43.1 0.7 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Zn-ribbon_8 PF09723.10 KIY69765.1 - 0.011 15.8 5.5 1 9.6 0.2 2.6 2 0 0 2 2 2 0 Zinc ribbon domain Auto_anti-p27 PF06677.12 KIY69765.1 - 0.048 13.8 6.5 0.42 10.8 1.1 3.0 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) eIF-5_eIF-2B PF01873.17 KIY69765.1 - 0.11 12.4 6.2 4 7.4 0.9 2.5 2 0 0 2 2 2 0 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.12 KIY69765.1 - 0.19 11.3 8.2 0.15 11.6 1.3 2.6 2 0 0 2 2 2 0 TFIIB zinc-binding zinc_ribbon_4 PF13717.6 KIY69765.1 - 0.51 10.3 4.3 1.2 9.1 0.1 3.1 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_9 PF14369.6 KIY69765.1 - 0.59 10.4 2.7 0.81 10.0 0.8 2.2 2 0 0 2 2 2 0 zinc-ribbon Cytochrom_c3_2 PF14537.6 KIY69765.1 - 1.2 9.6 9.0 5.5 7.5 1.6 2.7 1 1 2 3 3 3 0 Cytochrome c3 zf-ribbon_3 PF13248.6 KIY69765.1 - 1.5 8.3 6.0 3.4 7.2 0.1 3.4 3 0 0 3 3 3 0 zinc-ribbon domain Elf1 PF05129.13 KIY69765.1 - 2.1 8.5 5.9 2.3 8.3 0.1 2.8 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like OTT_1508_deam PF14441.6 KIY69765.1 - 3.1 7.9 5.1 21 5.2 0.2 2.8 3 0 0 3 3 3 0 OTT_1508-like deaminase OrfB_Zn_ribbon PF07282.11 KIY69765.1 - 4 7.4 9.5 2.1 8.4 2.1 2.6 2 0 0 2 2 2 0 Putative transposase DNA-binding domain DZR PF12773.7 KIY69765.1 - 4.9 7.3 10.5 48 4.1 10.6 2.4 1 1 0 1 1 1 0 Double zinc ribbon AhpC-TSA PF00578.21 KIY69766.1 - 8.3e-37 125.9 0.0 1.2e-36 125.4 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.9 KIY69766.1 - 1.4e-14 53.6 0.0 2.4e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.10 KIY69766.1 - 5e-13 49.0 0.0 6.4e-13 48.7 0.0 1.1 1 0 0 1 1 1 1 Redoxin Glutaredoxin PF00462.24 KIY69767.1 - 1.1e-18 67.2 0.0 1.4e-18 66.8 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.6 KIY69767.1 - 0.0002 21.8 0.1 0.0003 21.2 0.1 1.4 1 1 0 1 1 1 1 Thioredoxin-like domain DUF836 PF05768.14 KIY69767.1 - 0.00057 20.2 0.0 0.00068 20.0 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_3 PF13192.6 KIY69767.1 - 0.0035 17.3 0.0 0.0056 16.7 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin domain Thioredoxin PF00085.20 KIY69767.1 - 0.043 13.8 0.1 0.063 13.3 0.1 1.3 1 1 0 1 1 1 0 Thioredoxin Thioredoxin_7 PF13899.6 KIY69767.1 - 0.14 12.4 0.0 0.27 11.4 0.0 1.6 1 1 0 1 1 1 0 Thioredoxin-like DSBA PF01323.20 KIY69767.1 - 0.15 11.8 0.2 0.4 10.4 0.1 1.7 2 0 0 2 2 2 0 DSBA-like thioredoxin domain RNase_H2_suC PF08615.11 KIY69768.1 - 3.9e-18 66.0 0.0 5.1e-18 65.6 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) DUF2834 PF11196.8 KIY69770.1 - 3.9e-09 36.7 18.6 0.00022 21.5 0.3 3.8 3 1 0 3 3 3 2 Protein of unknown function (DUF2834) zf-H2C2_5 PF13909.6 KIY69771.1 - 0.00021 21.0 4.0 0.0043 16.8 1.3 2.5 2 0 0 2 2 2 1 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 KIY69771.1 - 0.0065 16.9 5.8 0.18 12.4 0.3 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type FOXP-CC PF16159.5 KIY69771.1 - 0.058 14.0 0.1 0.058 14.0 0.1 2.2 2 1 1 3 3 3 0 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 KIY69771.1 - 0.19 12.6 5.9 0.28 12.1 0.7 2.8 3 0 0 3 3 3 0 C2H2-type zinc finger OrsD PF12013.8 KIY69771.1 - 0.21 12.0 6.0 9.1 6.8 2.4 2.6 2 0 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D DIOX_N PF14226.6 KIY69772.1 - 5.4e-19 69.1 1.3 2.4e-18 67.0 0.0 2.4 3 0 0 3 3 3 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KIY69772.1 - 7.5e-12 45.6 0.1 1.3e-11 44.8 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TAF1_subA PF14929.6 KIY69773.1 - 0.062 12.7 0.0 0.07 12.5 0.0 1.2 1 0 0 1 1 1 0 TAF RNA Polymerase I subunit A Img2 PF05046.14 KIY69774.1 - 7e-19 67.9 0.0 8.6e-19 67.6 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) BTB PF00651.31 KIY69778.1 - 5.4e-05 23.4 0.0 9.2e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Sulfate_transp PF00916.20 KIY69779.1 - 3.8e-89 299.1 17.4 5.5e-89 298.6 17.4 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KIY69779.1 - 2e-15 56.5 0.0 3.4e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 KIY69779.1 - 1.4e-05 25.3 0.0 4.2e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 STAS domain FAD_binding_4 PF01565.23 KIY69781.1 - 1.7e-09 37.5 0.0 0.00062 19.5 0.1 2.8 2 1 0 2 2 2 2 FAD binding domain BBE PF08031.12 KIY69781.1 - 5.3e-08 32.8 0.1 1e-07 31.9 0.1 1.4 1 0 0 1 1 1 1 Berberine and berberine like KH_1 PF00013.29 KIY69781.1 - 0.16 11.9 0.0 0.35 10.7 0.0 1.5 1 0 0 1 1 1 0 KH domain Aldo_ket_red PF00248.21 KIY69782.1 - 3.2e-44 151.3 0.2 1e-43 149.7 0.2 1.7 1 1 0 1 1 1 1 Aldo/keto reductase family Hydrolase_4 PF12146.8 KIY69783.1 - 8.1e-05 22.0 0.0 0.00022 20.5 0.0 1.7 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Con-6 PF10346.9 KIY69784.1 - 6.5e-42 141.3 8.3 4.8e-14 52.1 0.3 3.1 3 0 0 3 3 3 3 Conidiation protein 6 SpoIIIAH PF12685.7 KIY69784.1 - 0.081 12.7 2.6 7.5 6.3 0.1 2.9 1 1 2 3 3 3 0 SpoIIIAH-like protein PAG PF15347.6 KIY69786.1 - 0.0004 19.5 0.0 0.0006 18.9 0.0 1.3 1 0 0 1 1 1 1 Phosphoprotein associated with glycosphingolipid-enriched Mucin15 PF15672.5 KIY69786.1 - 0.001 18.7 0.1 0.001 18.7 0.1 1.9 2 0 0 2 2 2 1 Cell-membrane associated Mucin15 Tweety PF04906.13 KIY69786.1 - 0.0059 15.3 0.0 0.0085 14.8 0.0 1.1 1 0 0 1 1 1 1 Tweety DUF4690 PF15756.5 KIY69786.1 - 0.15 12.7 0.2 0.15 12.7 0.2 2.9 3 2 2 5 5 5 0 Small Novel Rich in Cartilage Adeno_E3_CR2 PF02439.15 KIY69786.1 - 0.2 11.5 0.2 0.68 9.7 0.0 1.9 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 Peptidase_C2 PF00648.21 KIY69787.1 - 6.1e-16 58.3 0.0 9.3e-16 57.7 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 KIY69787.1 - 2e-14 54.1 0.0 0.0002 21.7 0.0 5.0 3 2 0 3 3 3 2 Calpain large subunit, domain III MIT PF04212.18 KIY69787.1 - 8.5e-07 29.0 3.5 1.7e-06 28.0 3.5 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain E1-E2_ATPase PF00122.20 KIY69789.1 - 2.1e-49 167.5 0.5 2.1e-49 167.5 0.5 2.8 4 0 0 4 4 4 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KIY69789.1 - 4.1e-35 121.1 1.8 5.6e-35 120.7 0.3 2.0 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KIY69789.1 - 1.2e-18 68.1 3.5 3.3e-18 66.7 2.0 2.4 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KIY69789.1 - 2.4e-13 50.0 0.0 6.3e-12 45.4 0.0 2.8 3 0 0 3 3 3 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KIY69789.1 - 7.9e-09 35.1 0.0 1.7e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KIY69789.1 - 1.6e-05 24.8 1.7 0.0022 17.8 0.8 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase RseC_MucC PF04246.12 KIY69789.1 - 0.00012 22.0 0.4 0.00072 19.5 0.0 2.5 2 0 0 2 2 2 1 Positive regulator of sigma(E), RseC/MucC Glyco_hydro_71 PF03659.14 KIY69790.1 - 2.3e-127 424.9 9.0 2.9e-127 424.6 9.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Sacchrp_dh_NADP PF03435.18 KIY69793.1 - 1e-16 61.4 0.1 1.6e-16 60.7 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 KIY69793.1 - 0.0013 18.6 0.1 0.0023 17.8 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Shikimate_DH PF01488.20 KIY69793.1 - 0.014 15.4 0.0 0.023 14.7 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.24 KIY69793.1 - 0.033 14.6 0.0 0.11 12.9 0.0 1.9 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DUF1232 PF06803.12 KIY69793.1 - 0.038 13.8 0.0 0.074 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1232) Efg1 PF10153.9 KIY69795.1 - 1e-34 119.3 10.0 1e-34 119.3 10.0 1.9 2 0 0 2 2 2 1 rRNA-processing protein Efg1 MukF_M PF17192.4 KIY69795.1 - 0.09 12.5 0.2 0.14 11.8 0.2 1.4 1 0 0 1 1 1 0 MukF middle domain Cep57_MT_bd PF06657.13 KIY69795.1 - 0.25 11.8 5.0 0.08 13.4 1.5 1.9 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 FeoB_Cyto PF17910.1 KIY69795.1 - 0.42 11.2 3.8 1 9.9 3.7 2.0 1 1 0 1 1 1 0 FeoB cytosolic helical domain DUF1690 PF07956.11 KIY69795.1 - 5.4 7.4 14.6 0.32 11.4 6.1 2.5 2 2 0 2 2 2 0 Protein of Unknown function (DUF1690) IKI3 PF04762.12 KIY69796.1 - 1.7e-246 820.6 0.0 2e-191 638.4 0.0 2.1 1 1 1 2 2 2 2 IKI3 family ATPase_2 PF01637.18 KIY69798.1 - 4.4e-15 56.2 0.0 2.5e-07 30.8 0.0 2.2 2 0 0 2 2 2 2 ATPase domain predominantly from Archaea AAA_16 PF13191.6 KIY69798.1 - 1.1e-08 35.7 1.2 1.4e-07 32.0 1.2 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KIY69798.1 - 0.00041 20.8 0.0 0.17 12.3 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RNA12 PF10443.9 KIY69798.1 - 0.00052 18.9 0.0 0.01 14.6 0.0 2.1 2 0 0 2 2 2 1 RNA12 protein AAA_22 PF13401.6 KIY69798.1 - 0.0018 18.6 0.1 0.087 13.1 0.0 2.8 3 0 0 3 3 3 1 AAA domain ResIII PF04851.15 KIY69798.1 - 0.054 13.5 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_28 PF13521.6 KIY69798.1 - 0.071 13.3 0.1 0.24 11.7 0.1 2.0 1 1 0 1 1 1 0 AAA domain Aminotran_5 PF00266.19 KIY69799.1 - 1.9e-21 76.4 0.0 4.2e-21 75.3 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class-V UPF0014 PF03649.13 KIY69800.1 - 3.6e-70 236.1 21.7 4.2e-70 235.8 21.7 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0014) Tubulin_2 PF13809.6 KIY69800.1 - 0.18 11.0 0.1 0.25 10.5 0.1 1.2 1 0 0 1 1 1 0 Tubulin like Cyt_bd_oxida_II PF02322.15 KIY69801.1 - 0.013 14.9 0.6 0.034 13.5 0.1 1.8 2 0 0 2 2 2 0 Cytochrome bd terminal oxidase subunit II DUF2102 PF09875.9 KIY69803.1 - 0.23 11.2 0.0 0.6 9.9 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2102) Rit1_C PF17184.4 KIY69804.1 - 1.6e-95 319.7 0.0 2e-95 319.3 0.0 1.1 1 0 0 1 1 1 1 Rit1 N-terminal domain Init_tRNA_PT PF04179.12 KIY69804.1 - 1.3e-24 86.7 0.0 6.1e-24 84.4 0.0 2.0 2 0 0 2 2 2 1 Rit1 DUSP-like domain DUF4097 PF13349.6 KIY69805.1 - 0.12 11.7 1.0 0.71 9.2 1.1 1.8 1 1 0 1 1 1 0 Putative adhesin OPT PF03169.15 KIY69806.1 - 1.1e-179 599.1 45.3 1.3e-179 598.8 45.3 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Nop14 PF04147.12 KIY69807.1 - 0.65 8.1 4.3 0.81 7.8 4.3 1.1 1 0 0 1 1 1 0 Nop14-like family HAD PF12710.7 KIY69808.1 - 8.2e-22 78.5 0.0 1e-21 78.2 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 KIY69808.1 - 9.7e-07 28.4 0.0 2.1e-06 27.3 0.0 1.5 2 0 0 2 2 2 1 Putative Phosphatase Hydrolase PF00702.26 KIY69808.1 - 0.00045 20.6 1.0 0.042 14.1 0.0 3.0 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 KIY69808.1 - 0.0017 17.9 0.0 0.0051 16.4 0.0 1.8 1 1 1 2 2 2 1 Pyrimidine 5'-nucleotidase (UMPH-1) p450 PF00067.22 KIY69809.1 - 4.3e-23 81.8 0.0 6.8e-23 81.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Acetyltransf_7 PF13508.7 KIY69810.1 - 2.5e-05 24.6 0.0 4.6e-05 23.8 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIY69810.1 - 6.7e-05 23.1 0.0 9e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KIY69810.1 - 0.0015 18.5 0.0 0.002 18.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF4453 PF14627.6 KIY69810.1 - 0.044 13.9 0.0 1 9.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4453) CDH-cyt PF16010.5 KIY69812.1 - 1e-53 181.8 0.2 1.2e-53 181.5 0.2 1.1 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase MBG_2 PF18676.1 KIY69812.1 - 0.23 12.1 2.9 4.3 8.0 0.1 2.5 2 1 0 2 2 2 0 MBG domain (YGX type) SNF2_N PF00176.23 KIY69814.1 - 9.1e-49 166.0 0.4 2.5e-48 164.6 0.0 1.9 2 0 0 2 2 2 1 SNF2 family N-terminal domain zf-C3HC4_3 PF13920.6 KIY69814.1 - 2.8e-08 33.5 4.4 4.6e-08 32.8 4.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIY69814.1 - 5.1e-07 29.9 8.7 1e-06 29.0 8.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KIY69814.1 - 1.1e-06 28.4 7.5 2e-06 27.6 7.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KIY69814.1 - 1.4e-06 28.0 9.1 2.7e-06 27.1 9.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KIY69814.1 - 1e-05 25.3 6.7 1.9e-05 24.4 6.7 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KIY69814.1 - 0.00021 21.2 8.6 0.00038 20.4 8.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Helicase_C PF00271.31 KIY69814.1 - 0.00033 21.0 0.1 0.001 19.4 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_UBOX PF13445.6 KIY69814.1 - 0.0013 18.7 5.4 0.0044 17.0 5.3 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KIY69814.1 - 0.01 15.8 2.6 0.021 14.8 2.6 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KIY69814.1 - 0.027 14.7 6.6 0.065 13.5 6.6 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 KIY69814.1 - 0.092 12.9 7.7 0.18 12.0 7.7 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF913 PF06025.12 KIY69814.1 - 0.25 10.3 1.8 11 4.8 0.0 2.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) DZR PF12773.7 KIY69814.1 - 1.2 9.3 3.3 2.6 8.1 3.3 1.6 1 0 0 1 1 1 0 Double zinc ribbon zf-RING_4 PF14570.6 KIY69814.1 - 1.6 8.6 6.2 3.3 7.6 6.2 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Uso1_p115_head PF04869.14 KIY69815.1 - 3.3e-46 157.8 0.0 2.3e-43 148.5 0.0 3.4 2 1 0 2 2 2 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.13 KIY69815.1 - 1.7e-11 44.6 22.0 1.7e-11 44.6 22.0 1.6 2 0 0 2 2 1 1 Uso1 / p115 like vesicle tethering protein, C terminal region Spc7 PF08317.11 KIY69815.1 - 0.001 18.1 4.4 0.0016 17.4 4.4 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein TMF_TATA_bd PF12325.8 KIY69815.1 - 0.0011 19.1 12.6 0.0028 17.9 12.6 1.7 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding NPV_P10 PF05531.12 KIY69815.1 - 0.0098 16.3 4.5 0.027 14.9 3.1 2.5 2 1 0 2 2 2 1 Nucleopolyhedrovirus P10 protein SlyX PF04102.12 KIY69815.1 - 0.024 15.3 7.5 1.9 9.2 1.9 3.0 1 1 1 2 2 2 0 SlyX MMS19_N PF14500.6 KIY69815.1 - 0.034 13.7 0.1 0.39 10.3 0.1 2.3 1 1 1 2 2 2 0 Dos2-interacting transcription regulator of RNA-Pol-II NDT80_PhoG PF05224.12 KIY69815.1 - 0.057 13.6 0.4 1.2 9.3 0.2 2.2 2 0 0 2 2 2 0 NDT80 / PhoG like DNA-binding family Ribosomal_60s PF00428.19 KIY69815.1 - 0.066 13.8 12.5 18 6.0 0.1 3.7 3 0 0 3 3 3 0 60s Acidic ribosomal protein TMF_DNA_bd PF12329.8 KIY69815.1 - 0.12 12.3 14.8 0.27 11.3 6.0 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding COMP PF11598.8 KIY69815.1 - 0.12 12.8 0.2 0.44 11.1 0.2 1.9 1 0 0 1 1 1 0 Cartilage oligomeric matrix protein T2SSF PF00482.23 KIY69815.1 - 0.19 11.7 2.4 0.58 10.1 2.4 1.8 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F MIF4G_like_2 PF09090.11 KIY69815.1 - 0.23 10.9 5.0 0.13 11.7 2.9 1.6 2 0 0 2 2 2 0 MIF4G like ABC_tran_CTD PF16326.5 KIY69815.1 - 0.28 11.5 10.8 53 4.2 9.2 3.6 2 1 1 3 3 3 0 ABC transporter C-terminal domain UPF0242 PF06785.11 KIY69815.1 - 0.34 11.0 4.8 0.71 9.9 4.8 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF16 PF01519.16 KIY69815.1 - 0.46 11.0 7.9 7.1 7.2 0.2 2.4 1 1 1 2 2 2 0 Protein of unknown function DUF16 Seryl_tRNA_N PF02403.22 KIY69815.1 - 1.5 9.1 7.8 3.8 7.8 7.8 1.7 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Fib_alpha PF08702.10 KIY69815.1 - 1.8 8.8 5.6 4.1 7.6 5.6 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family FliJ PF02050.16 KIY69815.1 - 1.8 8.8 12.5 22 5.3 12.6 2.2 1 1 0 1 1 1 0 Flagellar FliJ protein Pec_lyase_C PF00544.19 KIY69816.1 - 1.3e-43 149.1 4.8 1.8e-43 148.6 4.8 1.1 1 0 0 1 1 1 1 Pectate lyase Ank_4 PF13637.6 KIY69817.1 - 1.4e-05 25.5 0.0 0.0038 17.8 0.0 3.0 1 1 2 3 3 3 1 Ankyrin repeats (many copies) zf-MYND PF01753.18 KIY69817.1 - 3.3e-05 23.9 17.3 3.3e-05 23.9 17.3 2.0 2 0 0 2 2 2 1 MYND finger Ank_5 PF13857.6 KIY69817.1 - 0.12 12.7 0.0 3.4 8.1 0.0 2.7 2 1 0 2 2 2 0 Ankyrin repeats (many copies) Ank_4 PF13637.6 KIY69818.1 - 0.00014 22.3 0.0 0.0024 18.4 0.0 2.6 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Aminotran_5 PF00266.19 KIY69819.1 - 3.6e-24 85.4 0.0 5.8e-24 84.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DSPc PF00782.20 KIY69820.1 - 1.3e-30 105.9 0.0 1.5e-30 105.7 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 KIY69820.1 - 0.00087 19.6 0.0 0.0013 19.0 0.0 1.3 1 0 0 1 1 1 1 Rit1 DUSP-like domain CDKN3 PF05706.12 KIY69820.1 - 0.00097 18.8 0.0 0.0014 18.4 0.0 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase PF00102.27 KIY69820.1 - 0.01 15.4 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 KIY69820.1 - 0.069 12.7 0.0 0.13 11.9 0.0 1.5 2 0 0 2 2 2 0 Tyrosine phosphatase family ER_lumen_recept PF00810.18 KIY69822.1 - 1.3e-56 191.6 8.5 1.8e-56 191.0 8.5 1.2 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 KIY69822.1 - 0.00063 19.5 8.3 0.051 13.3 0.2 4.0 3 1 1 4 4 4 2 PQ loop repeat LPD39 PF18858.1 KIY69823.1 - 0.06 13.4 0.1 0.1 12.7 0.1 1.3 1 0 0 1 1 1 0 Large polyvalent protein associated domain 39 N2227 PF07942.12 KIY69824.1 - 3.4e-43 147.8 0.0 5.1e-33 114.4 0.0 2.1 1 1 1 2 2 2 2 N2227-like protein Methyltransf_23 PF13489.6 KIY69824.1 - 0.009 15.9 0.0 0.023 14.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIY69824.1 - 0.021 15.6 0.0 0.2 12.4 0.0 2.3 2 1 0 2 2 2 0 Methyltransferase domain Trp_halogenase PF04820.14 KIY69826.1 - 1.6e-05 24.0 0.1 0.0072 15.2 0.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase FAD_oxidored PF12831.7 KIY69826.1 - 0.18 11.1 0.0 1.2 8.4 0.0 2.0 1 1 0 1 1 1 0 FAD dependent oxidoreductase adh_short_C2 PF13561.6 KIY69827.1 - 6.6e-53 179.7 3.8 8.7e-53 179.3 3.8 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIY69827.1 - 7.5e-49 165.8 2.0 9.3e-49 165.5 2.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIY69827.1 - 1.1e-11 44.9 1.1 1.8e-11 44.3 1.1 1.2 1 0 0 1 1 1 1 KR domain Coq4 PF05019.13 KIY69828.1 - 1.9e-98 328.2 0.0 2.4e-98 327.9 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 p450 PF00067.22 KIY69829.1 - 7.8e-70 235.9 0.0 9.2e-70 235.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ribosomal_S8 PF00410.19 KIY69831.1 - 3.4e-24 85.2 0.1 4.4e-24 84.8 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Ribosomal_S17e PF00833.18 KIY69832.1 - 3.2e-58 195.0 0.1 3.8e-58 194.7 0.1 1.1 1 0 0 1 1 1 1 Ribosomal S17 GFA PF04828.14 KIY69834.1 - 3.2e-12 46.6 1.8 2e-05 24.9 0.1 2.8 2 1 1 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme NAD_binding_10 PF13460.6 KIY69835.1 - 1.3e-11 44.7 0.1 2e-11 44.1 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KIY69835.1 - 4.5e-11 42.7 0.1 7.6e-11 42.0 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KIY69835.1 - 8.6e-05 22.1 0.0 0.001 18.6 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KIY69835.1 - 9e-05 21.8 0.0 0.045 12.9 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein Sacchrp_dh_NADP PF03435.18 KIY69835.1 - 9.8e-05 22.6 0.1 0.00021 21.6 0.1 1.6 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain DapB_N PF01113.20 KIY69835.1 - 0.0011 19.0 0.1 0.0019 18.3 0.1 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus 3Beta_HSD PF01073.19 KIY69835.1 - 0.0015 17.6 0.0 0.0063 15.6 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 KIY69835.1 - 0.0019 18.6 0.0 0.0036 17.7 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KIY69835.1 - 0.055 13.5 0.1 0.1 12.7 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF5056 PF16479.5 KIY69836.1 - 0.067 13.4 1.1 0.14 12.4 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF5056) ADH_zinc_N PF00107.26 KIY69837.1 - 1.6e-17 63.7 0.0 2.5e-17 63.1 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KIY69837.1 - 2e-14 53.4 0.0 5.7e-14 51.9 0.0 1.6 2 0 0 2 2 2 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 KIY69837.1 - 4.9e-08 34.1 0.0 8.5e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase p450 PF00067.22 KIY69838.1 - 6.6e-72 242.7 0.0 8.3e-72 242.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ndc1_Nup PF09531.10 KIY69839.1 - 0.58 8.8 4.2 0.62 8.7 4.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TraV PF09676.10 KIY69839.1 - 1.2 10.1 13.0 0.37 11.8 10.3 1.5 2 0 0 2 2 2 0 Type IV conjugative transfer system lipoprotein (TraV) IDO PF01231.18 KIY69843.1 - 7.3e-129 430.3 0.1 1.1e-127 426.5 0.1 1.9 1 1 0 1 1 1 1 Indoleamine 2,3-dioxygenase HCO3_cotransp PF00955.21 KIY69845.1 - 7.2e-73 246.1 8.5 1.8e-37 129.3 0.1 2.9 1 1 1 2 2 2 2 HCO3- transporter family zf-MYND PF01753.18 KIY69846.1 - 2.1e-09 37.3 11.2 5.9e-09 35.9 11.2 1.9 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KIY69846.1 - 0.22 11.9 5.8 0.69 10.3 5.8 1.9 1 1 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding MFS_1 PF07690.16 KIY69847.1 - 2.9e-39 135.0 31.2 2.9e-39 135.0 31.2 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIY69847.1 - 3.4e-07 29.5 15.7 3.4e-07 29.5 15.7 1.8 2 0 0 2 2 2 1 Sugar (and other) transporter Polysacc_deac_1 PF01522.21 KIY69848.1 - 2.5e-28 98.4 0.0 3.6e-28 97.9 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase ADH_zinc_N PF00107.26 KIY69849.1 - 3.5e-14 52.9 0.7 6.2e-14 52.1 0.7 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIY69849.1 - 8.9e-11 41.6 0.0 3.9e-10 39.6 0.0 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KIY69849.1 - 4.1e-05 24.7 0.0 7.1e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Semialdhyde_dh PF01118.24 KIY69849.1 - 0.081 13.4 0.4 0.13 12.7 0.4 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Fungal_trans PF04082.18 KIY69850.1 - 1.4e-25 89.9 0.0 2.2e-25 89.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY69850.1 - 3.2e-09 36.7 9.7 5.7e-09 36.0 9.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.13 KIY69850.1 - 0.0044 17.2 0.0 0.01 16.0 0.0 1.6 1 0 0 1 1 1 1 Gal4-like dimerisation domain APH PF01636.23 KIY69852.1 - 2.8e-19 70.0 3.3 4.6e-19 69.3 3.3 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KIY69852.1 - 0.028 14.0 0.0 0.044 13.4 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase PBP1_TM PF14812.6 KIY69853.1 - 7.7 7.0 6.5 8.3 6.9 0.9 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Glyco_hydro_7 PF00840.20 KIY69854.1 - 1.8e-209 695.9 15.6 2e-209 695.8 15.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 TPR_2 PF07719.17 KIY69855.1 - 9.7e-29 97.1 28.3 0.00049 20.0 0.0 13.8 15 1 1 16 16 15 7 Tetratricopeptide repeat TPR_1 PF00515.28 KIY69855.1 - 2e-24 84.3 13.2 0.00016 21.4 0.1 10.5 12 0 0 12 12 12 5 Tetratricopeptide repeat TPR_19 PF14559.6 KIY69855.1 - 7.6e-22 77.6 23.5 0.00098 19.6 1.5 10.6 10 1 1 11 11 10 7 Tetratricopeptide repeat TPR_8 PF13181.6 KIY69855.1 - 1.9e-19 68.1 16.3 0.011 15.9 0.0 11.1 12 0 0 12 12 10 5 Tetratricopeptide repeat TPR_12 PF13424.6 KIY69855.1 - 4.3e-18 65.4 44.2 6.7e-07 29.5 2.0 11.1 8 4 3 11 11 11 5 Tetratricopeptide repeat TPR_7 PF13176.6 KIY69855.1 - 1.7e-09 37.0 11.4 0.11 12.5 0.0 9.0 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_6 PF13174.6 KIY69855.1 - 4e-09 36.5 29.5 0.00011 22.6 0.8 10.9 14 0 0 14 14 13 3 Tetratricopeptide repeat TPR_11 PF13414.6 KIY69855.1 - 2.5e-06 27.1 12.5 1.7 8.4 0.0 9.5 7 3 2 9 9 9 1 TPR repeat ANAPC3 PF12895.7 KIY69855.1 - 1.5e-05 25.1 6.9 1.2 9.4 0.1 6.2 5 1 1 6 6 6 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 KIY69855.1 - 1.9e-05 25.1 42.8 0.85 10.6 0.1 13.8 13 3 4 17 17 14 3 Tetratricopeptide repeat TPR_17 PF13431.6 KIY69855.1 - 5.5e-05 23.3 12.1 9 6.9 0.0 9.5 11 0 0 11 11 9 1 Tetratricopeptide repeat TPR_16 PF13432.6 KIY69855.1 - 7.8e-05 23.2 37.8 0.16 12.7 0.0 10.9 10 2 5 15 15 12 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KIY69855.1 - 0.22 11.6 8.4 24 5.1 0.4 5.4 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat DUF4129 PF13559.6 KIY69857.1 - 0.073 13.3 0.1 0.16 12.2 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4129) F-box-like PF12937.7 KIY69857.1 - 0.14 12.1 0.7 0.45 10.4 0.7 2.0 1 1 0 1 1 1 0 F-box-like Piwi PF02171.17 KIY69858.1 - 6.5e-78 262.0 0.0 9.3e-78 261.5 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 KIY69858.1 - 3.3e-13 50.4 0.0 1.2e-12 48.6 0.0 2.0 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 KIY69858.1 - 2.4e-09 36.7 0.0 9.1e-09 34.9 0.0 2.0 1 0 0 1 1 1 1 Argonaute linker 1 domain PAZ PF02170.22 KIY69858.1 - 0.011 15.6 0.0 0.026 14.3 0.0 1.6 1 0 0 1 1 1 0 PAZ domain ArgoL2 PF16488.5 KIY69858.1 - 0.021 15.2 0.0 0.072 13.5 0.0 2.0 1 0 0 1 1 1 0 Argonaute linker 2 domain Fungal_trans PF04082.18 KIY69860.1 - 2e-08 33.6 0.3 3.9e-08 32.7 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY69860.1 - 0.0029 17.7 9.1 0.0054 16.8 9.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-H2C2_2 PF13465.6 KIY69861.1 - 6.4e-08 32.7 28.9 2.4e-05 24.6 0.7 4.9 5 0 0 5 5 5 3 Zinc-finger double domain zf-H2C2_5 PF13909.6 KIY69861.1 - 0.00056 19.6 0.5 0.00056 19.6 0.5 5.4 6 0 0 6 6 5 3 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 KIY69861.1 - 0.0011 19.3 1.8 0.024 15.1 0.4 5.4 6 1 0 6 6 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIY69861.1 - 0.0011 19.6 28.4 0.17 12.8 2.2 5.6 5 0 0 5 5 5 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KIY69861.1 - 0.024 14.9 0.9 16 5.9 0.0 3.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KIY69861.1 - 0.068 13.6 5.9 0.18 12.2 0.0 3.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 KIY69861.1 - 0.089 13.1 11.5 0.85 10.0 2.0 2.3 1 1 1 2 2 2 0 C2H2-type zinc ribbon Rad54_N PF08658.10 KIY69861.1 - 0.12 12.5 0.9 0.67 10.1 0.3 2.0 2 0 0 2 2 2 0 Rad54 N terminal OrsD PF12013.8 KIY69861.1 - 0.33 11.4 12.8 13 6.3 0.4 4.3 3 2 1 4 4 4 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-Di19 PF05605.12 KIY69861.1 - 0.44 10.9 22.3 0.59 10.5 6.4 3.2 1 1 3 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding FOXP-CC PF16159.5 KIY69861.1 - 1.8 9.2 11.7 24 5.7 0.1 4.5 3 2 2 5 5 5 0 FOXP coiled-coil domain EF1G PF00647.19 KIY69862.1 - 3.4e-41 139.6 0.0 7e-41 138.6 0.0 1.5 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 KIY69862.1 - 6.3e-12 45.5 0.7 5.8e-11 42.5 0.0 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KIY69862.1 - 5e-07 30.0 0.0 1.5e-06 28.4 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KIY69862.1 - 9.6e-07 29.1 0.0 1.8e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KIY69862.1 - 1.4e-06 28.4 0.7 3.6e-06 27.1 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KIY69862.1 - 4.8e-06 26.5 0.0 1.4e-05 25.0 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 KIY69862.1 - 0.0002 21.1 0.0 0.00074 19.3 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Pox_Ag35 PF03286.14 KIY69862.1 - 1.6 8.5 8.8 2.4 7.9 8.8 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein OAD_gamma PF04277.13 KIY69862.1 - 2.9 8.5 8.4 6.5 7.4 8.4 1.6 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain BTB PF00651.31 KIY69863.1 - 0.0014 18.8 0.1 0.0099 16.1 0.1 2.2 1 1 0 1 1 1 1 BTB/POZ domain DUF1748 PF08520.10 KIY69863.1 - 0.069 13.1 0.1 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF1748) RB_B PF01857.20 KIY69863.1 - 0.14 12.2 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Retinoblastoma-associated protein B domain BTB PF00651.31 KIY69864.1 - 0.007 16.6 0.1 0.044 14.0 0.1 2.1 1 1 0 1 1 1 1 BTB/POZ domain BPD_transp_2 PF02653.16 KIY69865.1 - 0.02 14.1 0.1 0.02 14.1 0.1 2.0 2 0 0 2 2 2 0 Branched-chain amino acid transport system / permease component DJ-1_PfpI PF01965.24 KIY69866.1 - 5.4e-12 45.8 0.0 7.1e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family GMC_oxred_N PF00732.19 KIY69867.1 - 6.2e-55 186.7 0.0 8.1e-55 186.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIY69867.1 - 2.5e-30 105.9 0.0 5e-30 104.9 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KIY69867.1 - 0.0023 17.1 0.1 0.0036 16.4 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Aminotran_1_2 PF00155.21 KIY69867.1 - 0.027 13.7 0.0 2.5 7.2 0.0 2.1 2 0 0 2 2 2 0 Aminotransferase class I and II Thi4 PF01946.17 KIY69867.1 - 0.033 13.4 0.1 0.065 12.5 0.1 1.4 1 0 0 1 1 1 0 Thi4 family NAD_binding_8 PF13450.6 KIY69867.1 - 0.056 13.7 0.1 0.2 11.9 0.1 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 KIY69867.1 - 0.18 10.6 0.0 0.27 10.1 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase bZIP_1 PF00170.21 KIY69868.1 - 4.1e-09 36.4 0.7 6.4e-09 35.8 0.7 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KIY69868.1 - 3.3e-08 33.5 2.3 5.1e-08 32.9 2.3 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KIY69868.1 - 0.0025 18.3 1.6 0.0044 17.5 1.6 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor GvpL_GvpF PF06386.11 KIY69868.1 - 0.079 12.9 0.6 0.11 12.4 0.6 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF G-alpha PF00503.20 KIY69869.1 - 5.2e-96 321.9 0.0 6.2e-96 321.6 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KIY69869.1 - 1.1e-13 51.0 1.5 9.7e-09 34.9 0.1 3.0 2 2 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KIY69869.1 - 0.00077 18.9 0.2 0.21 10.9 0.0 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 KIY69869.1 - 0.0053 17.0 0.1 2.2 8.5 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 KIY69869.1 - 0.055 13.2 0.1 0.12 12.2 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain CPT PF07931.12 KIY69869.1 - 0.079 12.8 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein DUF1043 PF06295.12 KIY69869.1 - 0.082 12.9 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) MMR_HSR1 PF01926.23 KIY69869.1 - 0.1 12.7 0.0 5.1 7.2 0.0 2.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase Hemerythrin PF01814.23 KIY69870.1 - 1.4e-09 38.7 3.6 1.9e-09 38.3 3.6 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain GxGYxYP_N PF16216.5 KIY69870.1 - 0.081 13.1 0.1 0.1 12.8 0.1 1.2 1 0 0 1 1 1 0 GxGYxY sequence motif in domain of unknown function N-terminal DUF4185 PF13810.6 KIY69871.1 - 7.6e-14 51.7 3.7 9.8e-14 51.3 3.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4185) tRNA-synt_2 PF00152.20 KIY69872.1 - 2.9e-80 269.7 0.0 3.7e-80 269.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KIY69872.1 - 2.7e-08 33.7 0.0 4.3e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KIY69872.1 - 0.029 13.9 0.0 1.9 7.9 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) TPR_MLP1_2 PF07926.12 KIY69873.1 - 2.6e-23 82.5 19.1 2.6e-23 82.5 19.1 9.0 4 4 4 8 8 8 4 TPR/MLP1/MLP2-like protein ZapB PF06005.12 KIY69873.1 - 0.00082 19.8 2.9 0.00082 19.8 2.9 12.7 4 3 3 7 7 7 1 Cell division protein ZapB Leu_zip PF15294.6 KIY69873.1 - 0.0011 18.5 10.2 0.0011 18.5 10.2 7.0 1 1 5 7 7 7 2 Leucine zipper DUF3800 PF12686.7 KIY69873.1 - 0.34 11.6 2.0 1e+02 3.5 2.7 4.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) F-box-like PF12937.7 KIY69874.1 - 5.2e-05 23.1 5.9 0.00018 21.3 4.4 2.6 2 1 0 2 2 2 1 F-box-like F-box PF00646.33 KIY69874.1 - 0.0059 16.4 3.2 19 5.3 2.6 3.6 3 0 0 3 3 3 2 F-box domain Hydrolase_4 PF12146.8 KIY69875.1 - 2.5e-50 171.0 0.0 3e-50 170.7 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KIY69875.1 - 1.6e-11 45.3 0.0 2e-11 44.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KIY69875.1 - 6.7e-10 39.0 0.0 2.1e-08 34.1 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KIY69875.1 - 0.017 14.6 0.3 0.17 11.4 0.3 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 KIY69875.1 - 0.12 12.2 0.3 1.7 8.4 0.0 2.3 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Cellulase PF00150.18 KIY69876.1 - 9.2e-10 38.4 0.3 2e-09 37.3 0.2 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Radical_SAM PF04055.21 KIY69876.1 - 0.049 14.0 0.0 0.083 13.3 0.0 1.3 1 0 0 1 1 1 0 Radical SAM superfamily EthD PF07110.11 KIY69878.1 - 9.8e-12 45.9 0.1 1.3e-11 45.5 0.1 1.1 1 0 0 1 1 1 1 EthD domain SinI PF08671.10 KIY69878.1 - 0.05 13.4 0.1 0.098 12.5 0.1 1.5 1 0 0 1 1 1 0 Anti-repressor SinI CM_2 PF01817.21 KIY69879.1 - 2.1e-06 28.0 0.2 0.0012 19.2 0.0 2.7 3 0 0 3 3 3 2 Chorismate mutase type II Glyco_hydro_12 PF01670.16 KIY69880.1 - 1.7e-33 116.4 9.8 2e-33 116.2 9.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 zf-RING_2 PF13639.6 KIY69881.1 - 5e-11 42.8 2.7 5e-11 42.8 2.7 1.9 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 KIY69881.1 - 6.4e-11 41.8 2.1 6.4e-11 41.8 2.1 2.0 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 KIY69881.1 - 2.6e-07 30.5 1.1 5.1e-07 29.5 1.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain PA PF02225.22 KIY69881.1 - 7.2e-07 29.1 0.0 1.5e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 PA domain zf-C3HC4_2 PF13923.6 KIY69881.1 - 2e-05 24.3 2.6 4.1e-05 23.3 2.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KIY69881.1 - 8.4e-05 22.5 1.9 0.0071 16.3 0.1 2.6 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KIY69881.1 - 0.00012 21.8 1.4 0.00029 20.6 1.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIY69881.1 - 0.00013 21.8 1.9 0.00013 21.8 1.9 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KIY69881.1 - 0.00022 21.4 6.4 0.0011 19.2 5.5 2.6 2 1 0 2 2 2 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KIY69881.1 - 0.015 15.1 2.8 0.015 15.1 2.8 1.8 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KIY69881.1 - 0.025 14.6 2.2 0.048 13.7 1.1 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KIY69881.1 - 0.13 11.9 1.9 0.29 10.8 1.9 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 KIY69881.1 - 0.28 11.4 3.0 1.9 8.7 3.0 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain Polysacc_deac_1 PF01522.21 KIY69883.1 - 0.00016 21.6 0.0 0.00027 20.9 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase ABC_tran PF00005.27 KIY69884.1 - 2e-25 89.9 0.0 4.9e-25 88.6 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KIY69884.1 - 1.3e-10 41.6 1.1 0.00048 20.0 0.1 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KIY69884.1 - 5.1e-07 29.3 0.1 0.0081 15.6 0.1 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 KIY69884.1 - 7.7e-07 29.1 0.0 0.00017 21.4 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 KIY69884.1 - 0.004 17.7 0.0 0.0074 16.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KIY69884.1 - 0.0056 17.1 0.1 0.022 15.1 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KIY69884.1 - 0.0088 15.8 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 KIY69884.1 - 0.019 14.7 0.0 0.036 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_27 PF13514.6 KIY69884.1 - 0.026 14.1 0.0 0.048 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KIY69884.1 - 0.04 14.2 0.0 0.59 10.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KIY69884.1 - 0.053 12.8 0.0 0.096 12.0 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin NepR PF18557.1 KIY69884.1 - 0.13 11.9 0.9 0.36 10.5 0.2 2.1 2 0 0 2 2 2 0 Anti-sigma factor NepR Phosphodiest PF01663.22 KIY69885.1 - 3.8e-79 266.9 2.8 5e-79 266.5 2.8 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Acetyltransf_10 PF13673.7 KIY69887.1 - 4.9e-09 36.2 0.0 6.8e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIY69887.1 - 1.2e-08 35.2 0.1 2.1e-08 34.4 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KIY69887.1 - 4.4e-07 30.2 0.0 5.9e-07 29.8 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIY69887.1 - 1.3e-05 25.0 0.0 2e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 KIY69887.1 - 4.9e-05 23.4 0.0 7.9e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Q_salvage PF10343.9 KIY69889.1 - 3.1e-92 309.1 0.0 3.9e-92 308.8 0.0 1.1 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family Na_H_Exchanger PF00999.21 KIY69891.1 - 1.1e-38 133.1 36.5 1.5e-38 132.6 36.5 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family SK_channel PF03530.14 KIY69891.1 - 8.3 6.4 7.9 0.74 9.8 1.4 2.3 1 1 1 2 2 2 0 Calcium-activated SK potassium channel ADH_zinc_N PF00107.26 KIY69892.1 - 2.6e-12 46.8 0.0 4.1e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIY69892.1 - 1.5e-07 31.2 0.0 3.3e-07 30.1 0.0 1.5 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KIY69892.1 - 5.8e-06 27.4 0.0 9.4e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DnaJ PF00226.31 KIY69893.1 - 4e-12 46.1 1.9 2.1e-11 43.8 1.9 2.2 1 1 0 1 1 1 1 DnaJ domain Folliculin PF11704.8 KIY69893.1 - 8.8 6.2 8.5 9.3 6.1 0.0 2.4 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport ADH_zinc_N PF00107.26 KIY69894.1 - 1.3e-12 47.8 0.0 2e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIY69894.1 - 7.3e-08 32.3 0.0 1.5e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KIY69894.1 - 2.9e-07 31.6 0.0 4.2e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Peptidase_M20 PF01546.28 KIY69896.1 - 3e-35 121.8 0.0 3.7e-35 121.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KIY69896.1 - 4.5e-09 36.2 0.0 9.7e-09 35.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KIY69896.1 - 0.0093 15.7 0.0 0.021 14.5 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M28 Ax_dynein_light PF10211.9 KIY69896.1 - 0.037 14.0 0.0 0.061 13.3 0.0 1.2 1 0 0 1 1 1 0 Axonemal dynein light chain GYF PF02213.16 KIY69897.1 - 0.092 12.4 0.3 0.15 11.7 0.3 1.3 1 0 0 1 1 1 0 GYF domain FtsJ PF01728.19 KIY69898.1 - 1.7e-46 158.6 0.0 2.2e-46 158.2 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Pkinase PF00069.25 KIY69899.1 - 1.2e-61 208.4 0.0 8.9e-61 205.5 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY69899.1 - 1.2e-37 129.6 0.0 1.1e-23 83.8 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KIY69899.1 - 0.00024 20.5 0.0 0.00052 19.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KIY69899.1 - 0.0014 18.6 9.8 0.056 13.4 0.0 3.3 3 0 0 3 3 3 2 Phosphotransferase enzyme family DMAP1_like PF17024.5 KIY69899.1 - 0.16 12.1 3.8 0.34 11.0 0.2 2.9 3 0 0 3 3 3 0 Putative DMAP1-like UPF0061 PF02696.14 KIY69899.1 - 0.69 8.6 8.6 1.1 8.0 8.6 1.2 1 0 0 1 1 1 0 Uncharacterized ACR, YdiU/UPF0061 family Zn_clus PF00172.18 KIY69900.1 - 3.2e-08 33.6 6.5 3.2e-08 33.6 6.5 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2189 PF09955.9 KIY69900.1 - 0.11 12.8 0.1 0.49 10.7 0.1 2.0 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2189) Osmo_CC PF08946.10 KIY69900.1 - 0.14 12.4 0.6 1.5 9.2 0.3 2.2 2 0 0 2 2 2 0 Osmosensory transporter coiled coil Abhydrolase_6 PF12697.7 KIY69901.1 - 3e-16 60.7 1.8 4.3e-16 60.2 1.8 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIY69901.1 - 0.00044 19.6 0.0 0.00074 18.9 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Spo7 PF03907.13 KIY69902.1 - 1.3e-33 116.3 2.7 2.1e-32 112.4 2.7 2.1 1 1 0 1 1 1 1 Spo7-like protein Tmemb_18A PF09771.9 KIY69902.1 - 0.084 13.3 1.3 0.43 11.0 1.3 2.1 1 1 0 1 1 1 0 Transmembrane protein 188 DUF4227 PF14004.6 KIY69902.1 - 0.096 12.7 0.1 0.25 11.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4227) Aminotran_1_2 PF00155.21 KIY69903.1 - 2.8e-56 191.3 0.0 3.3e-56 191.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KIY69903.1 - 0.052 12.1 0.0 0.12 10.9 0.0 1.5 1 1 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KIY69903.1 - 0.12 11.3 0.0 0.27 10.1 0.0 1.5 2 0 0 2 2 2 0 Aminotransferase class-V Cellulase PF00150.18 KIY69904.1 - 6.7e-52 176.6 0.9 8.7e-52 176.3 0.9 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 KIY69904.1 - 2e-13 50.0 9.1 2e-13 50.0 9.1 3.1 4 0 0 4 4 4 1 Fungal cellulose binding domain F-box PF00646.33 KIY69905.1 - 1.1e-05 25.1 2.0 1.7e-05 24.5 0.4 2.2 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KIY69905.1 - 0.00088 19.1 3.3 0.0035 17.2 0.3 2.8 2 0 0 2 2 2 1 F-box-like F-box_4 PF15966.5 KIY69905.1 - 0.0032 17.3 0.0 0.009 15.9 0.0 1.8 1 0 0 1 1 1 1 F-box LytTR PF04397.15 KIY69905.1 - 0.05 13.8 0.7 0.12 12.6 0.1 1.8 2 0 0 2 2 2 0 LytTr DNA-binding domain Linocin_M18 PF04454.12 KIY69905.1 - 0.07 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Encapsulating protein for peroxidase DZR PF12773.7 KIY69905.1 - 4.2 7.5 5.9 8.3 6.5 0.5 2.9 3 0 0 3 3 3 0 Double zinc ribbon Spindle_Spc25 PF08234.12 KIY69906.1 - 7.6e-20 70.9 0.0 1.3e-19 70.1 0.0 1.4 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 Spc7 PF08317.11 KIY69906.1 - 0.0075 15.2 11.1 0.012 14.5 11.2 1.3 1 1 0 1 1 1 1 Spc7 kinetochore protein FUSC PF04632.12 KIY69906.1 - 0.035 12.7 5.7 0.046 12.3 5.7 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family CENP-F_leu_zip PF10473.9 KIY69906.1 - 0.078 13.0 10.2 0.1 12.6 9.0 1.7 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_16 PF13191.6 KIY69906.1 - 0.27 11.6 1.8 0.38 11.1 1.8 1.2 1 0 0 1 1 1 0 AAA ATPase domain Atg14 PF10186.9 KIY69906.1 - 2.4 7.2 6.5 3.1 6.8 6.5 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 XRN_M PF17846.1 KIY69906.1 - 2.7 6.9 6.8 3.5 6.5 6.8 1.1 1 0 0 1 1 1 0 Xrn1 helical domain JIP_LZII PF16471.5 KIY69906.1 - 8.1 6.7 11.1 7.9 6.7 1.5 2.8 2 1 1 3 3 3 0 JNK-interacting protein leucine zipper II APG6_N PF17675.1 KIY69906.1 - 8.9 6.8 15.1 28 5.2 15.1 1.8 1 1 0 1 1 1 0 Apg6 coiled-coil region PEARLI-4 PF05278.12 KIY69906.1 - 9.6 5.7 11.2 2 8.0 6.5 1.8 1 1 1 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) Prok-RING_2 PF14445.6 KIY69907.1 - 0.053 13.7 0.0 0.085 13.0 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 HSP20 PF00011.21 KIY69908.1 - 1.5e-25 89.3 0.1 1.9e-25 89.0 0.1 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KIY69908.1 - 1.3e-09 37.5 0.0 1.8e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 HSP20-like domain found in ArsA BON PF04972.17 KIY69908.1 - 0.027 14.8 0.1 0.057 13.7 0.0 1.6 2 0 0 2 2 2 0 BON domain CS PF04969.16 KIY69908.1 - 0.13 13.3 0.0 0.19 12.8 0.0 1.4 1 0 0 1 1 1 0 CS domain F-box-like PF12937.7 KIY69909.1 - 3.6e-08 33.2 0.7 9.5e-08 31.8 0.7 1.8 1 0 0 1 1 1 1 F-box-like DUF899 PF05988.12 KIY69909.1 - 0.011 15.2 0.0 0.019 14.5 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF899) F-box PF00646.33 KIY69909.1 - 0.41 10.6 4.8 6.7 6.7 1.5 3.0 2 0 0 2 2 2 0 F-box domain DER1 PF04511.15 KIY69910.1 - 1.4e-30 106.7 0.2 1.6e-30 106.4 0.2 1.0 1 0 0 1 1 1 1 Der1-like family HSP20 PF00011.21 KIY69911.1 - 7.1e-27 93.5 0.1 9.3e-27 93.2 0.1 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KIY69911.1 - 2.7e-11 42.9 0.0 3.7e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 HSP20-like domain found in ArsA BON PF04972.17 KIY69911.1 - 0.0064 16.8 0.1 0.034 14.5 0.0 2.0 2 0 0 2 2 2 1 BON domain 4HBT_2 PF13279.6 KIY69912.1 - 2.9e-06 27.8 0.0 4.3e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT_2 PF13279.6 KIY69913.1 - 4.3e-05 24.0 0.0 8.1e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF2271 PF10029.9 KIY69913.1 - 0.15 11.7 0.0 0.33 10.6 0.0 1.5 1 0 0 1 1 1 0 Predicted periplasmic protein (DUF2271) SRP19 PF01922.17 KIY69915.1 - 2.5e-24 86.0 0.0 3.2e-24 85.7 0.0 1.2 1 0 0 1 1 1 1 SRP19 protein HSP20 PF00011.21 KIY69917.1 - 6.7e-27 93.6 0.1 8.8e-27 93.2 0.1 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KIY69917.1 - 1.1e-11 44.1 0.0 1.6e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 HSP20-like domain found in ArsA BON PF04972.17 KIY69917.1 - 0.0092 16.3 0.1 0.051 13.9 0.0 2.0 2 0 0 2 2 2 1 BON domain CS PF04969.16 KIY69917.1 - 0.094 13.7 0.0 0.14 13.2 0.0 1.3 1 0 0 1 1 1 0 CS domain HMA PF00403.26 KIY69917.1 - 0.11 13.0 0.0 1.9 9.0 0.0 2.1 2 0 0 2 2 2 0 Heavy-metal-associated domain FKBP26_C PF18046.1 KIY69917.1 - 0.15 12.2 0.0 21 5.3 0.0 2.3 2 0 0 2 2 2 0 FKBP26_C-terminal AP3D1 PF06375.11 KIY69919.1 - 2.5 8.3 12.2 0.059 13.6 4.8 1.9 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 ETF_QO PF05187.13 KIY69920.1 - 3.6e-36 123.4 1.6 6.2e-29 100.2 0.1 2.5 1 1 1 2 2 2 2 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S NAD_binding_8 PF13450.6 KIY69920.1 - 8e-07 29.2 0.1 2.2e-06 27.8 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KIY69920.1 - 4e-05 23.4 2.8 7e-05 22.6 1.1 2.0 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIY69920.1 - 4.6e-05 22.8 0.0 6.6e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KIY69920.1 - 0.00012 21.4 0.0 0.00074 18.8 0.1 1.9 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 KIY69920.1 - 0.00029 20.1 1.9 0.00046 19.4 1.9 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KIY69920.1 - 0.00039 19.3 0.9 0.00055 18.7 0.9 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 KIY69920.1 - 0.00076 18.8 0.6 0.0012 18.2 0.6 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KIY69920.1 - 0.0013 18.0 0.3 0.0021 17.4 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 KIY69920.1 - 0.0028 17.7 0.5 0.0091 16.0 0.3 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding Fer4_7 PF12838.7 KIY69920.1 - 0.02 15.5 0.5 0.061 13.9 0.5 1.8 2 0 0 2 2 1 0 4Fe-4S dicluster domain FAD_oxidored PF12831.7 KIY69920.1 - 0.022 14.1 0.2 0.035 13.5 0.2 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KIY69920.1 - 0.029 13.4 0.3 0.047 12.7 0.3 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein K_oxygenase PF13434.6 KIY69920.1 - 0.13 11.3 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.22 KIY69920.1 - 0.17 10.9 0.2 0.26 10.3 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Fer4_6 PF12837.7 KIY69920.1 - 1.8 8.8 4.3 1.3 9.2 1.1 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain zf-C2H2 PF00096.26 KIY69921.1 - 4.3e-09 36.3 15.2 4.6e-05 23.6 2.1 3.8 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIY69921.1 - 2.1e-05 25.0 10.2 0.0016 19.1 0.6 3.8 4 0 0 4 4 4 2 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KIY69921.1 - 0.0073 16.0 4.6 0.044 13.5 0.8 2.6 2 0 0 2 2 2 1 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KIY69921.1 - 0.018 15.3 0.1 0.055 13.8 0.1 1.8 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KIY69921.1 - 0.018 15.0 2.8 0.066 13.2 0.1 2.8 3 0 0 3 3 3 0 C2H2-type zinc finger DUF3039 PF11238.8 KIY69921.1 - 0.11 12.2 0.4 0.23 11.3 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3039) zf-H2C2_2 PF13465.6 KIY69921.1 - 0.16 12.4 12.8 4.5 7.9 0.3 3.7 3 0 0 3 3 3 0 Zinc-finger double domain zf-Di19 PF05605.12 KIY69921.1 - 0.61 10.4 4.8 0.29 11.4 2.3 1.8 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding FOXP-CC PF16159.5 KIY69921.1 - 0.65 10.7 3.2 18 6.1 0.1 2.3 1 1 1 2 2 2 0 FOXP coiled-coil domain GAGA PF09237.11 KIY69921.1 - 2.4 8.1 7.1 5.2 6.9 1.1 2.4 1 1 1 2 2 2 0 GAGA factor Glyco_hydro_43 PF04616.14 KIY69923.1 - 4.3e-29 101.7 0.0 5.6e-29 101.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Polysacc_deac_1 PF01522.21 KIY69924.1 - 9.6e-07 28.7 0.0 1.5e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Abhydrolase_2 PF02230.16 KIY69925.1 - 8e-14 52.0 0.0 1.7e-13 50.9 0.0 1.6 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 KIY69925.1 - 0.0011 19.7 0.2 0.0014 19.3 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 KIY69925.1 - 0.11 12.4 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 KIY69925.1 - 0.13 11.9 0.0 6.5 6.3 0.0 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold AAA_16 PF13191.6 KIY69927.1 - 0.033 14.6 0.0 0.19 12.1 0.0 2.2 2 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 KIY69927.1 - 0.15 12.3 0.3 12 6.2 0.3 2.5 1 1 0 1 1 1 0 AAA domain MFS_1 PF07690.16 KIY69929.1 - 3.2e-12 46.1 31.7 2.9e-10 39.6 16.5 3.2 3 0 0 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.6 KIY69929.1 - 2.1e-11 43.1 20.1 8.8e-11 41.0 20.1 2.1 1 1 0 1 1 1 1 MFS/sugar transport protein BT1 PF03092.16 KIY69929.1 - 0.051 11.8 7.4 0.012 13.9 3.8 1.7 2 0 0 2 2 2 0 BT1 family DUF1634 PF07843.11 KIY69929.1 - 2 8.6 7.3 0.81 9.8 0.3 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF1634) SecY PF00344.20 KIY69930.1 - 1.8e-72 244.2 10.1 2.3e-72 243.8 10.1 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 KIY69930.1 - 7.9e-19 67.2 0.2 2.2e-18 65.8 0.2 1.8 1 0 0 1 1 1 1 Plug domain of Sec61p DUF2929 PF11151.8 KIY69930.1 - 0.26 11.6 7.7 0.17 12.2 1.6 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2929) F-box-like PF12937.7 KIY69932.1 - 0.011 15.6 0.1 1.1 9.2 0.0 2.7 2 0 0 2 2 2 0 F-box-like SnoaL_2 PF12680.7 KIY69933.1 - 6.3e-08 33.2 0.0 8.7e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain Pmp3 PF01679.17 KIY69934.1 - 3.1e-19 68.9 2.6 3.6e-19 68.7 2.6 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Thymidylat_synt PF00303.19 KIY69935.1 - 1.8e-106 355.2 0.0 2e-106 355.0 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase TM_helix PF05552.12 KIY69936.1 - 0.06 13.3 0.3 0.12 12.4 0.3 1.4 1 0 0 1 1 1 0 Conserved TM helix DUF1688 PF07958.11 KIY69937.1 - 1.7e-176 587.0 0.0 2e-176 586.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) PHP PF02811.19 KIY69938.1 - 1.1e-09 38.8 0.3 3.4e-09 37.2 0.3 1.7 1 1 0 1 1 1 1 PHP domain Pkinase PF00069.25 KIY69939.1 - 7.6e-74 248.4 0.0 9.4e-74 248.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY69939.1 - 4.1e-32 111.5 0.0 5.9e-32 111.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY69939.1 - 2.5e-06 27.0 0.0 6.1e-06 25.8 0.0 1.6 1 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KIY69939.1 - 9.9e-06 24.6 0.0 1.8e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KIY69939.1 - 0.00065 19.1 0.0 0.0012 18.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIY69939.1 - 0.018 14.9 0.0 0.039 13.9 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family SNF5 PF04855.12 KIY69941.1 - 1.9e-60 204.6 0.6 3.7e-60 203.7 0.6 1.5 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 zf-MYND PF01753.18 KIY69942.1 - 1.7e-12 47.2 13.8 1.7e-12 47.2 13.8 2.0 2 0 0 2 2 2 1 MYND finger zf-C6H2 PF15801.5 KIY69942.1 - 0.011 16.1 7.8 0.011 16.1 7.8 2.1 2 1 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 KIY69943.1 - 2.4e-11 43.5 17.2 2.4e-11 43.5 17.2 2.0 2 0 0 2 2 2 1 MYND finger Peptidase_C14 PF00656.22 KIY69944.1 - 4.8e-16 59.5 0.0 3.2e-14 53.5 0.0 2.2 1 1 0 1 1 1 1 Caspase domain Metallothio_11 PF02066.15 KIY69944.1 - 0.031 14.4 0.1 0.065 13.4 0.1 1.5 1 0 0 1 1 1 0 Metallothionein family 11 WD40 PF00400.32 KIY69945.1 - 2e-21 75.9 8.8 1.1e-05 26.1 0.0 6.7 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY69945.1 - 0.00095 19.4 0.0 0.098 13.0 0.0 3.5 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 KIY69945.1 - 0.035 12.9 0.0 10 4.7 0.0 3.1 2 1 0 2 2 2 0 Nup133 N terminal like Cytochrom_D1 PF02239.16 KIY69945.1 - 0.037 12.6 0.1 0.49 8.9 0.1 2.2 1 1 0 1 1 1 0 Cytochrome D1 heme domain WD40_like PF17005.5 KIY69945.1 - 0.11 11.8 0.0 14 4.9 0.0 2.5 2 0 0 2 2 2 0 WD40-like domain HBM PF16591.5 KIY69946.1 - 0.0022 17.4 3.8 0.0037 16.7 3.8 1.4 1 1 0 1 1 1 1 Helical bimodular sensor domain APG6_N PF17675.1 KIY69946.1 - 0.014 15.9 6.7 0.017 15.6 6.7 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region HD_3 PF13023.6 KIY69946.1 - 0.025 14.5 1.1 0.031 14.2 1.1 1.1 1 0 0 1 1 1 0 HD domain Med29 PF11568.8 KIY69946.1 - 0.03 14.5 0.1 0.038 14.2 0.1 1.2 1 0 0 1 1 1 0 Mediator complex subunit 29 ATG16 PF08614.11 KIY69946.1 - 0.031 14.5 6.7 0.038 14.2 6.7 1.0 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Rabaptin PF03528.15 KIY69946.1 - 0.036 12.8 3.3 0.038 12.7 3.3 1.1 1 0 0 1 1 1 0 Rabaptin FUSC PF04632.12 KIY69946.1 - 0.16 10.5 0.7 0.16 10.4 0.7 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family F-box-like PF12937.7 KIY69947.1 - 0.016 15.1 0.2 0.038 13.9 0.1 1.6 2 0 0 2 2 2 0 F-box-like DUF202 PF02656.15 KIY69947.1 - 0.056 13.9 0.4 0.12 12.8 0.2 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF202) Abhydrolase_6 PF12697.7 KIY69948.1 - 1.7e-19 71.3 0.8 2.2e-19 70.9 0.8 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIY69948.1 - 5.6e-05 22.5 0.0 0.0021 17.4 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 KIY69951.1 - 9.1e-14 51.8 0.0 1.5e-13 51.1 0.0 1.4 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 KIY69951.1 - 0.00068 20.3 0.7 0.00085 20.0 0.7 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 KIY69951.1 - 0.022 14.6 0.0 0.031 14.1 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 KIY69951.1 - 0.16 11.6 0.1 7.8 6.1 0.0 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold Polysacc_deac_1 PF01522.21 KIY69952.1 - 3.7e-16 59.1 0.0 5.7e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 KIY69952.1 - 3.6e-06 26.8 0.0 1.2e-05 25.0 0.0 1.9 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) DUF2194 PF09960.9 KIY69952.1 - 0.088 11.1 0.0 0.12 10.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2194) F-box-like PF12937.7 KIY69956.1 - 5.9e-07 29.3 1.0 1.1e-06 28.4 1.0 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY69956.1 - 4.1e-05 23.4 0.9 4.1e-05 23.4 0.9 1.7 2 0 0 2 2 2 1 F-box domain ApoO PF09769.9 KIY69957.1 - 2.4e-24 85.8 0.0 3.2e-24 85.4 0.0 1.2 1 0 0 1 1 1 1 Apolipoprotein O DEAD PF00270.29 KIY69958.1 - 8.6e-45 152.6 0.0 1.7e-44 151.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIY69958.1 - 3.7e-19 69.1 0.0 1.9e-18 66.8 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KIY69958.1 - 7.8e-19 67.7 0.0 1.6e-18 66.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KIY69958.1 - 1.1e-05 25.6 0.0 3.2e-05 24.0 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KIY69959.1 - 3.2e-17 62.9 0.0 1.4e-16 60.8 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIY69959.1 - 1e-13 51.6 0.0 8.1e-13 48.7 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIY69959.1 - 3.8e-08 33.5 0.0 3.5e-06 27.1 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.14 KIY69959.1 - 0.14 11.5 0.2 0.22 10.8 0.2 1.2 1 0 0 1 1 1 0 SecA DEAD-like domain PhoH PF02562.16 KIY69959.1 - 0.16 11.4 0.1 0.34 10.3 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA-ATPase_like PF09820.9 KIY69960.1 - 0.076 12.4 0.1 0.17 11.3 0.0 1.5 1 1 0 1 1 1 0 Predicted AAA-ATPase Utp12 PF04003.12 KIY69960.1 - 0.14 12.5 1.5 1.1 9.6 0.3 2.2 2 0 0 2 2 2 0 Dip2/Utp12 Family DUF4407 PF14362.6 KIY69960.1 - 0.37 10.1 6.6 0.59 9.4 6.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ARGLU PF15346.6 KIY69960.1 - 0.66 9.9 8.2 1.2 9.0 8.2 1.5 1 1 0 1 1 1 0 Arginine and glutamate-rich 1 DASH_Spc19 PF08287.11 KIY69960.1 - 9.9 6.0 15.3 6.9 6.5 0.1 3.0 2 1 1 3 3 3 0 Spc19 AAA_18 PF13238.6 KIY69962.1 - 1.5e-31 109.6 0.0 2.1e-31 109.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KIY69962.1 - 5.6e-06 26.8 0.0 1.3e-05 25.6 0.0 1.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 KIY69962.1 - 3.2e-05 24.2 0.1 9.2e-05 22.7 0.0 1.8 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 KIY69962.1 - 4.7e-05 23.6 0.1 0.019 15.1 0.0 2.2 1 1 1 2 2 2 1 AAA domain dNK PF01712.19 KIY69962.1 - 0.00017 21.5 0.1 0.23 11.3 0.0 2.2 2 0 0 2 2 2 2 Deoxynucleoside kinase AAA_17 PF13207.6 KIY69962.1 - 0.00026 21.4 0.0 0.00066 20.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KIY69962.1 - 0.00032 21.0 0.0 0.00055 20.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain SKI PF01202.22 KIY69962.1 - 0.0011 19.1 0.0 0.0017 18.5 0.0 1.3 1 1 0 1 1 1 1 Shikimate kinase Thymidylate_kin PF02223.17 KIY69962.1 - 0.0084 15.8 0.0 1.6 8.4 0.0 2.1 2 0 0 2 2 2 1 Thymidylate kinase AAA_16 PF13191.6 KIY69962.1 - 0.01 16.2 0.1 0.035 14.5 0.0 1.9 1 1 0 1 1 1 0 AAA ATPase domain KTI12 PF08433.10 KIY69962.1 - 0.01 15.3 0.0 0.021 14.3 0.0 1.5 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Herpes_Helicase PF02689.14 KIY69962.1 - 0.011 13.7 0.1 1.2 7.0 0.0 2.0 2 0 0 2 2 2 0 Helicase MeaB PF03308.16 KIY69962.1 - 0.019 14.0 1.1 0.08 11.9 0.1 2.0 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NTPase_1 PF03266.15 KIY69962.1 - 0.02 14.8 0.2 0.27 11.1 0.0 2.2 2 0 0 2 2 2 0 NTPase RuvB_N PF05496.12 KIY69962.1 - 0.024 14.4 0.0 0.04 13.7 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Arnt_C PF18583.1 KIY69962.1 - 0.034 13.8 1.1 4.2 7.0 0.0 2.4 3 0 0 3 3 2 0 Aminoarabinose transferase C-terminal domain ATPase PF06745.13 KIY69962.1 - 0.036 13.4 0.5 0.66 9.3 0.0 2.1 2 0 0 2 2 2 0 KaiC ABC_tran PF00005.27 KIY69962.1 - 0.036 14.6 0.0 0.058 13.9 0.0 1.6 1 1 0 1 1 1 0 ABC transporter CPT PF07931.12 KIY69962.1 - 0.043 13.6 0.0 0.077 12.8 0.0 1.5 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Rad17 PF03215.15 KIY69962.1 - 0.046 13.6 0.0 0.07 13.0 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain Zeta_toxin PF06414.12 KIY69962.1 - 0.049 12.9 0.0 0.089 12.1 0.0 1.5 2 0 0 2 2 2 0 Zeta toxin AAA_14 PF13173.6 KIY69962.1 - 0.051 13.6 0.0 0.13 12.3 0.0 1.6 1 1 0 2 2 2 0 AAA domain DUF2075 PF09848.9 KIY69962.1 - 0.074 12.3 0.0 0.15 11.3 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.6 KIY69962.1 - 0.076 12.7 0.0 0.14 11.9 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KIY69962.1 - 0.081 13.3 0.1 0.19 12.0 0.1 1.6 1 0 0 1 1 1 0 AAA domain PerC PF06069.11 KIY69962.1 - 0.084 13.1 0.3 0.23 11.7 0.2 1.7 2 0 0 2 2 2 0 PerC transcriptional activator RNA_helicase PF00910.22 KIY69962.1 - 0.092 13.1 0.0 0.2 12.1 0.0 1.6 2 0 0 2 2 1 0 RNA helicase AAA_30 PF13604.6 KIY69962.1 - 0.099 12.4 0.2 0.26 11.0 0.1 1.8 2 0 0 2 2 2 0 AAA domain ADK PF00406.22 KIY69962.1 - 0.11 12.6 0.0 2.6 8.1 0.0 2.2 2 0 0 2 2 2 0 Adenylate kinase CoaE PF01121.20 KIY69962.1 - 0.11 12.2 0.1 4 7.1 0.0 2.1 2 0 0 2 2 2 0 Dephospho-CoA kinase Viral_helicase1 PF01443.18 KIY69962.1 - 0.14 11.8 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AA_permease PF00324.21 KIY69963.1 - 1.1e-128 429.9 37.9 1.3e-128 429.6 37.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KIY69963.1 - 4.7e-33 114.6 40.7 6.2e-33 114.3 40.7 1.1 1 0 0 1 1 1 1 Amino acid permease DUF3382 PF11862.8 KIY69963.1 - 3.5 8.0 15.4 0.53 10.6 0.8 3.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3382) ECH_1 PF00378.20 KIY69964.1 - 4.2e-23 81.9 0.0 6.8e-23 81.3 0.0 1.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KIY69964.1 - 3e-16 59.8 0.0 3.7e-16 59.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Diphtheria_C PF02763.14 KIY69964.1 - 0.12 12.0 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Diphtheria toxin, C domain Aldo_ket_red PF00248.21 KIY69966.1 - 4.5e-54 183.6 0.0 5.1e-54 183.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family OTU PF02338.19 KIY69967.1 - 2e-24 86.5 0.0 4.9e-24 85.2 0.0 1.6 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 KIY69967.1 - 0.0015 18.0 0.0 1.1 8.6 0.0 2.2 1 1 1 2 2 2 2 Peptidase C65 Otubain NAM-associated PF14303.6 KIY69967.1 - 0.013 16.2 4.2 0.019 15.7 4.2 1.2 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain DUF722 PF05263.11 KIY69968.1 - 0.12 12.6 0.0 0.17 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF722) Adaptin_N PF01602.20 KIY69969.1 - 1.7e-122 409.7 6.5 2.2e-122 409.3 6.5 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KIY69969.1 - 1.1e-56 191.3 3.9 2.3e-52 177.3 0.1 3.7 2 1 1 3 3 3 3 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KIY69969.1 - 5.9e-14 52.2 9.6 7.8e-06 26.2 0.5 5.4 4 1 2 6 6 6 4 HEAT repeats HEAT PF02985.22 KIY69969.1 - 5.8e-07 29.2 6.9 0.14 12.5 0.2 6.9 8 0 0 8 8 8 2 HEAT repeat Arm PF00514.23 KIY69969.1 - 0.00033 20.6 1.1 0.096 12.8 0.0 4.7 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 KIY69969.1 - 0.0036 16.9 0.1 0.081 12.5 0.0 3.0 3 0 0 3 3 3 1 CLASP N terminal UNC45-central PF11701.8 KIY69969.1 - 0.021 14.8 0.3 2.1 8.3 0.1 3.0 2 1 0 2 2 2 0 Myosin-binding striated muscle assembly central HEAT_EZ PF13513.6 KIY69969.1 - 0.04 14.4 1.0 1.2e+02 3.3 0.1 5.0 5 0 0 5 5 5 0 HEAT-like repeat CENP-B_dimeris PF09026.10 KIY69969.1 - 5.2 7.5 9.4 11 6.4 9.4 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Pneumo_NS1 PF03438.13 KIY69970.1 - 0.049 13.8 0.1 0.092 12.9 0.1 1.5 1 0 0 1 1 1 0 Pneumovirus NS1 protein adh_short PF00106.25 KIY69971.1 - 7.8e-54 182.1 1.6 1.1e-53 181.6 1.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIY69971.1 - 7.1e-35 120.6 1.6 8.8e-35 120.4 1.6 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIY69971.1 - 4.2e-14 52.9 0.4 5.5e-14 52.5 0.4 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KIY69971.1 - 0.00098 18.6 0.0 0.0014 18.1 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) THF_DHG_CYH_C PF02882.19 KIY69971.1 - 0.0021 17.4 0.4 0.014 14.7 0.1 2.2 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.8 KIY69971.1 - 0.0026 17.5 0.9 0.0053 16.5 0.9 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Helicase_RecD PF05127.14 KIY69971.1 - 0.0051 16.7 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 Helicase Epimerase PF01370.21 KIY69971.1 - 0.0077 15.7 0.9 0.021 14.3 0.9 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 KIY69971.1 - 0.038 13.9 0.2 0.063 13.2 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 KIY69971.1 - 0.1 12.0 0.0 0.27 10.6 0.0 1.6 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase HSP70 PF00012.20 KIY69973.1 - 1.5e-260 865.5 6.1 1.7e-260 865.4 6.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KIY69973.1 - 2.9e-16 59.2 0.3 4.2e-15 55.4 0.1 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 KIY69973.1 - 0.0032 17.2 0.0 0.0073 16.0 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 KIY69973.1 - 0.061 12.6 0.2 0.15 11.3 0.2 1.6 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase zf-MYND PF01753.18 KIY69974.1 - 0.00017 21.6 13.5 0.00032 20.7 13.5 1.4 1 0 0 1 1 1 1 MYND finger LELP1 PF15042.6 KIY69974.1 - 0.33 11.3 8.6 0.65 10.4 8.6 1.4 1 0 0 1 1 1 0 Late cornified envelope-like proline-rich protein 1 2OG-FeII_Oxy_2 PF13532.6 KIY69975.1 - 1.9e-37 129.4 0.0 2.4e-34 119.2 0.0 2.3 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily Kelch_2 PF07646.15 KIY69976.1 - 0.069 13.2 0.4 0.14 12.2 0.4 1.5 1 0 0 1 1 1 0 Kelch motif LETM1 PF07766.13 KIY69977.1 - 1.1e-101 339.7 0.9 1.1e-101 339.7 0.9 2.2 2 0 0 2 2 2 1 LETM1-like protein EF-hand_6 PF13405.6 KIY69977.1 - 8.8e-05 22.1 0.4 7 6.9 0.0 4.3 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 KIY69977.1 - 0.00026 20.8 0.1 0.0015 18.3 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain pair SAP PF02037.27 KIY69977.1 - 0.00034 20.3 0.1 0.004 16.9 0.0 2.8 2 0 0 2 2 2 1 SAP domain EF-hand_7 PF13499.6 KIY69977.1 - 0.00094 19.6 5.4 0.37 11.3 0.2 4.8 4 1 0 4 4 4 1 EF-hand domain pair EF-hand_1 PF00036.32 KIY69977.1 - 0.0014 18.0 1.7 0.51 10.0 0.0 4.4 5 0 0 5 5 5 1 EF hand ABC_tran PF00005.27 KIY69977.1 - 0.11 13.0 4.1 0.1 13.1 2.3 1.9 2 0 0 2 2 2 0 ABC transporter DALR_1 PF05746.15 KIY69977.1 - 0.42 10.8 8.9 0.58 10.3 5.5 2.6 2 1 0 2 2 2 0 DALR anticodon binding domain SET PF00856.28 KIY69977.1 - 0.49 10.8 4.3 0.91 9.9 3.6 1.9 1 1 0 1 1 1 0 SET domain Helo_like_N PF17111.5 KIY69978.1 - 8.3e-15 54.7 0.2 2.6e-14 53.1 0.1 1.8 1 1 0 1 1 1 1 Fungal N-terminal domain of STAND proteins Ank_2 PF12796.7 KIY69978.1 - 4.8e-14 52.7 0.4 3.7e-13 49.9 0.1 2.6 3 0 0 3 3 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KIY69978.1 - 7.3e-11 42.4 7.8 3.3e-09 37.1 0.1 5.0 5 0 0 5 5 4 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KIY69978.1 - 5.6e-10 39.3 3.0 9e-07 29.1 0.2 3.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIY69978.1 - 7.4e-10 38.2 3.3 0.025 15.1 0.0 5.4 6 0 0 6 6 4 2 Ankyrin repeat NACHT PF05729.12 KIY69978.1 - 4.1e-09 36.6 0.0 9.7e-09 35.4 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Ank PF00023.30 KIY69978.1 - 1.5e-08 34.7 6.6 0.00094 19.5 0.1 5.2 4 0 0 4 4 4 2 Ankyrin repeat AAA_16 PF13191.6 KIY69978.1 - 9.6e-07 29.3 0.1 3.7e-06 27.4 0.1 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KIY69978.1 - 0.0001 22.6 0.1 0.00074 19.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.20 KIY69978.1 - 0.031 14.2 0.0 0.058 13.3 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA PF00004.29 KIY69978.1 - 0.036 14.5 0.0 0.15 12.5 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) HeLo PF14479.6 KIY69978.1 - 0.052 13.4 1.0 0.11 12.3 0.4 1.9 1 1 1 2 2 2 0 Prion-inhibition and propagation NB-ARC PF00931.22 KIY69978.1 - 0.065 12.4 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_14 PF13173.6 KIY69978.1 - 0.14 12.2 0.0 1.8 8.6 0.0 2.3 1 1 0 1 1 1 0 AAA domain Utp13 PF08625.11 KIY69978.1 - 0.9 9.4 3.3 3.2 7.7 0.1 3.0 3 0 0 3 3 3 0 Utp13 specific WD40 associated domain Wbp11 PF09429.10 KIY69978.1 - 1.9 8.9 3.8 3.4 8.1 0.5 2.7 2 1 1 3 3 3 0 WW domain binding protein 11 ox_reductase_C PF08635.10 KIY69979.1 - 5.4e-71 236.8 0.1 7.8e-71 236.3 0.1 1.2 1 0 0 1 1 1 1 Putative oxidoreductase C terminal domain GFO_IDH_MocA PF01408.22 KIY69979.1 - 1.8e-23 83.6 0.0 3.3e-23 82.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KIY69979.1 - 0.0059 16.6 0.0 0.011 15.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Ax_dynein_light PF10211.9 KIY69980.1 - 0.00033 20.7 2.9 0.00038 20.5 2.9 1.1 1 0 0 1 1 1 1 Axonemal dynein light chain Rx_N PF18052.1 KIY69980.1 - 0.0014 18.8 3.4 0.0022 18.2 3.4 1.2 1 0 0 1 1 1 1 Rx N-terminal domain Caldesmon PF02029.15 KIY69980.1 - 0.0064 15.3 4.9 0.008 15.0 4.9 1.1 1 0 0 1 1 1 1 Caldesmon UPF0242 PF06785.11 KIY69980.1 - 0.013 15.6 3.3 0.017 15.3 3.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus YjcZ PF13990.6 KIY69980.1 - 0.05 13.0 0.4 0.065 12.6 0.4 1.2 1 0 0 1 1 1 0 YjcZ-like protein Herpes_UL6 PF01763.16 KIY69980.1 - 0.065 11.8 3.5 0.083 11.4 3.5 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like T2SSF PF00482.23 KIY69980.1 - 0.093 12.7 0.4 0.13 12.2 0.4 1.2 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F IFP_35_N PF07334.13 KIY69980.1 - 0.79 9.8 4.7 1.6 8.8 4.7 1.5 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus DivIC PF04977.15 KIY69980.1 - 1.1 9.1 5.3 1.6 8.5 5.3 1.3 1 0 0 1 1 1 0 Septum formation initiator PIG-Y PF15159.6 KIY69981.1 - 2e-20 73.4 3.5 2.3e-20 73.3 3.5 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y DHHC PF01529.20 KIY69981.1 - 8.5 6.5 6.4 7.3 6.7 0.4 2.0 1 1 1 2 2 2 0 DHHC palmitoyltransferase zf-C2HE PF16278.5 KIY69982.1 - 1.8e-15 57.1 2.1 1.9e-15 57.0 0.4 2.0 2 0 0 2 2 2 1 C2HE / C2H2 / C2HC zinc-binding finger DcpS_C PF11969.8 KIY69982.1 - 5.6e-13 49.4 1.1 7.5e-13 49.0 0.1 1.7 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 KIY69982.1 - 2e-11 44.5 0.0 5.1e-11 43.2 0.0 1.6 1 0 0 1 1 1 1 HIT domain Gti1_Pac2 PF09729.9 KIY69984.1 - 1.9e-43 148.7 1.5 1.6e-33 116.3 0.2 2.1 1 1 1 2 2 2 2 Gti1/Pac2 family SHR3_chaperone PF08229.11 KIY69986.1 - 2.3e-35 121.3 0.0 2.7e-35 121.1 0.0 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 CPP1-like PF11833.8 KIY69986.1 - 0.047 13.3 0.2 0.11 12.1 0.2 1.6 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like RsfS PF02410.15 KIY69987.1 - 3.8e-06 27.2 0.0 6.3e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation Sfi1 PF08457.10 KIY69989.1 - 4.6e-26 91.5 101.4 1.3e-14 53.6 39.8 4.8 1 1 3 4 4 4 4 Sfi1 spindle body protein CLTH PF10607.9 KIY69989.1 - 1.3e-21 77.1 0.0 2.3e-21 76.2 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 KIY69989.1 - 2.6e-05 24.1 0.1 5.1e-05 23.2 0.1 1.5 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.12 KIY69989.1 - 0.089 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Rtf2 RING-finger Fungal_trans PF04082.18 KIY69992.1 - 6.7e-14 51.5 0.0 1.2e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY69992.1 - 0.00022 21.3 9.6 0.00036 20.6 9.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RabGAP-TBC PF00566.18 KIY69993.1 - 2.1e-28 99.5 0.1 3.7e-14 52.9 0.0 2.3 2 0 0 2 2 2 2 Rab-GTPase-TBC domain DUF1484 PF07363.11 KIY69993.1 - 0.054 14.5 0.0 0.15 13.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1484) Peptidase_C13 PF01650.18 KIY69994.1 - 2.1e-42 145.4 0.1 2.7e-42 145.1 0.1 1.1 1 0 0 1 1 1 1 Peptidase C13 family ArgoMid PF16487.5 KIY69994.1 - 0.17 12.2 0.0 0.43 10.9 0.0 1.7 1 0 0 1 1 1 0 Mid domain of argonaute RabGAP-TBC PF00566.18 KIY69995.1 - 1.3e-40 139.3 5.4 1.6e-38 132.6 1.5 2.3 2 0 0 2 2 2 2 Rab-GTPase-TBC domain OTT_1508_deam PF14441.6 KIY69996.1 - 6.4e-05 22.9 0.0 0.00016 21.6 0.0 1.7 1 0 0 1 1 1 1 OTT_1508-like deaminase OTT_1508_deam PF14441.6 KIY69997.1 - 2.1e-05 24.4 0.0 5.9e-05 23.0 0.0 1.8 1 1 0 1 1 1 1 OTT_1508-like deaminase Rad33 PF08730.10 KIY69997.1 - 0.012 15.6 0.0 0.029 14.3 0.0 1.7 2 0 0 2 2 2 0 Rad33 Ribosomal_S21e PF01249.18 KIY69998.1 - 2e-40 136.8 0.1 2.2e-40 136.6 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e Cupredoxin_1 PF13473.6 KIY69999.1 - 5.5e-05 23.2 0.0 0.28 11.3 0.0 2.5 2 0 0 2 2 2 2 Cupredoxin-like domain Copper-bind PF00127.20 KIY69999.1 - 0.0042 17.5 1.8 0.64 10.5 0.1 3.1 2 1 1 3 3 3 2 Copper binding proteins, plastocyanin/azurin family Cu_bind_like PF02298.17 KIY69999.1 - 0.0068 16.4 7.9 0.88 9.6 0.7 3.3 2 2 0 2 2 2 2 Plastocyanin-like domain DUF2187 PF09953.9 KIY69999.1 - 0.12 12.4 0.0 11 6.1 0.0 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2187) Cadherin_tail PF15974.5 KIY69999.1 - 0.14 12.5 1.4 0.22 11.8 1.4 1.3 1 0 0 1 1 1 0 Cadherin C-terminal cytoplasmic tail, catenin-binding region Pkinase_Tyr PF07714.17 KIY70000.1 - 1.2e-49 169.0 0.0 2.9e-49 167.7 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 KIY70000.1 - 8.9e-36 123.6 0.0 1.5e-25 90.0 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Kdo PF06293.14 KIY70000.1 - 0.0014 18.0 0.0 0.0033 16.8 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KIY70000.1 - 0.011 15.3 0.0 0.027 14.1 0.0 1.5 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 KIY70000.1 - 0.07 13.0 0.0 0.3 11.0 0.0 2.0 1 0 0 1 1 1 0 Phosphotransferase enzyme family G-patch PF01585.23 KIY70001.1 - 1.2e-09 37.9 3.8 3.5e-09 36.4 3.8 1.8 1 0 0 1 1 1 1 G-patch domain MMS1_N PF10433.9 KIY70002.1 - 1.4e-44 152.6 0.0 2.3e-44 151.8 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 KIY70002.1 - 8.7e-29 100.8 0.0 1.6e-28 100.0 0.0 1.4 1 0 0 1 1 1 1 CPSF A subunit region USP7_ICP0_bdg PF12436.8 KIY70003.1 - 5.8e-88 294.3 0.0 1e-86 290.2 0.0 2.5 3 0 0 3 3 3 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 KIY70003.1 - 7.8e-66 221.7 0.2 1.4e-62 211.1 0.1 2.5 2 0 0 2 2 2 2 Ubiquitin-specific protease C-terminal UCH PF00443.29 KIY70003.1 - 3e-50 171.1 0.1 4.8e-50 170.4 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KIY70003.1 - 1.8e-21 77.1 0.0 4.7e-21 75.7 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 KIY70003.1 - 3.5e-07 30.4 0.0 1.4e-06 28.4 0.0 2.0 2 0 0 2 2 2 1 MATH domain ubiquitin PF00240.23 KIY70003.1 - 0.0077 16.0 0.2 1.8 8.4 0.0 4.1 4 0 0 4 4 4 1 Ubiquitin family CRPV_capsid PF08762.10 KIY70003.1 - 0.025 14.2 0.0 0.051 13.2 0.0 1.4 1 0 0 1 1 1 0 CRPV capsid protein like Cys_rich_VLP PF14194.6 KIY70003.1 - 0.14 12.3 0.1 0.31 11.2 0.1 1.5 1 0 0 1 1 1 0 Cysteine-rich VLP CAMSAP_CC1 PF17095.5 KIY70003.1 - 2.4 8.1 8.0 5.3 7.0 8.0 1.5 1 0 0 1 1 1 0 Spectrin-binding region of Ca2+-Calmodulin DUF2956 PF11169.8 KIY70005.1 - 0.1 12.8 2.0 0.23 11.7 2.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) CytochromB561_N PF09786.9 KIY70005.1 - 0.93 8.4 5.3 2.1 7.3 5.3 1.5 1 0 0 1 1 1 0 Cytochrome B561, N terminal B56 PF01603.20 KIY70007.1 - 1.1e-186 620.8 4.9 1.3e-186 620.6 4.9 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.7 KIY70007.1 - 0.09 12.7 2.1 1.9 8.4 0.3 2.4 2 0 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Citrate_synt PF00285.21 KIY70008.1 - 1.6e-97 326.9 0.0 2e-97 326.5 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain DUF2269 PF10027.9 KIY70008.1 - 0.04 14.0 0.1 0.092 12.8 0.0 1.6 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2269) Sec66 PF09802.9 KIY70009.1 - 3.1e-55 186.5 0.0 3.7e-55 186.3 0.0 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 SpoU_methylase PF00588.19 KIY70010.1 - 4.6e-29 101.4 0.0 5.3e-29 101.2 0.0 1.0 1 0 0 1 1 1 1 SpoU rRNA Methylase family DUF765 PF05570.11 KIY70010.1 - 0.12 12.6 0.2 0.23 11.7 0.2 1.3 1 0 0 1 1 1 0 Circovirus protein of unknown function (DUF765) DNA_primase_lrg PF04104.14 KIY70011.1 - 8.7e-79 264.7 0.3 1.2e-78 264.2 0.3 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit B56 PF01603.20 KIY70012.1 - 7.1e-186 618.2 0.3 8.3e-186 617.9 0.3 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) B56 PF01603.20 KIY70013.1 - 8.1e-186 618.0 0.0 9.5e-186 617.7 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) DUF4097 PF13349.6 KIY70014.1 - 0.0017 17.7 0.0 0.0034 16.8 0.0 1.5 1 0 0 1 1 1 1 Putative adhesin FUN14 PF04930.15 KIY70015.1 - 5.3e-19 68.4 1.3 1.1e-18 67.4 1.3 1.5 1 0 0 1 1 1 1 FUN14 family Methyltr_RsmB-F PF01189.17 KIY70016.1 - 1.3e-76 256.8 0.0 1.8e-76 256.2 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 KIY70016.1 - 1.3e-08 35.2 0.0 4.4e-08 33.5 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of 16S rRNA methyltransferase RsmF Met_10 PF02475.16 KIY70016.1 - 0.0002 21.2 0.0 0.00034 20.4 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein PCMT PF01135.19 KIY70016.1 - 0.0091 15.8 0.0 0.014 15.1 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 KIY70016.1 - 0.023 14.5 0.0 0.043 13.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.12 KIY70016.1 - 0.054 13.2 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_25 PF13649.6 KIY70016.1 - 0.064 14.0 0.0 0.22 12.2 0.0 2.0 1 0 0 1 1 1 0 Methyltransferase domain SnoaL PF07366.12 KIY70017.1 - 3e-07 30.3 0.0 4e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 KIY70017.1 - 2.2e-06 28.2 0.0 3.5e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain Ebp2 PF05890.12 KIY70022.1 - 2.7e-86 289.5 14.0 5.4e-86 288.5 14.0 1.5 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 Glyco_hydro_18 PF00704.28 KIY70023.1 - 2.8e-75 254.0 9.7 4.9e-75 253.1 9.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_5_12 PF02839.14 KIY70023.1 - 0.0038 17.7 4.5 0.013 16.1 4.5 2.0 1 0 0 1 1 1 1 Carbohydrate binding domain CBM_5_12_2 PF14600.6 KIY70023.1 - 1.5 8.8 9.0 0.1 12.5 2.9 2.3 2 0 0 2 2 2 0 Cellulose-binding domain Zn_clus PF00172.18 KIY70024.1 - 1.9e-09 37.5 4.5 3.9e-09 36.5 4.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KIY70024.1 - 0.00067 18.8 0.3 0.0009 18.3 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Nuf2 PF03800.14 KIY70025.1 - 1.1e-29 103.3 0.0 3.2e-29 101.8 0.0 1.8 1 0 0 1 1 1 1 Nuf2 family DHR10 PF18595.1 KIY70025.1 - 7.2e-28 97.0 15.3 7.2e-28 97.0 15.3 3.6 3 0 0 3 3 3 1 Designed helical repeat protein 10 domain Laminin_II PF06009.12 KIY70025.1 - 0.0016 18.5 1.0 0.0016 18.5 1.0 3.8 1 1 2 3 3 3 1 Laminin Domain II Spc7 PF08317.11 KIY70025.1 - 0.0018 17.3 38.4 0.033 13.1 16.6 3.1 1 1 2 3 3 3 2 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 KIY70025.1 - 0.03 14.4 39.7 0.7 10.0 0.7 4.2 1 1 2 4 4 4 0 TPR/MLP1/MLP2-like protein DUF1664 PF07889.12 KIY70025.1 - 0.049 13.7 21.3 0.088 12.9 2.6 4.1 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) DUF4201 PF13870.6 KIY70025.1 - 0.074 12.8 37.6 0.04 13.6 10.8 3.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4201) KASH_CCD PF14662.6 KIY70025.1 - 0.076 12.8 38.8 0.48 10.2 12.5 3.2 1 1 2 3 3 3 0 Coiled-coil region of CCDC155 or KASH Filament PF00038.21 KIY70025.1 - 0.19 11.3 40.7 0.79 9.3 30.6 2.4 1 1 1 2 2 2 0 Intermediate filament protein MscS_porin PF12795.7 KIY70025.1 - 0.29 10.7 29.4 1.7 8.2 7.6 2.5 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain GAT PF03127.14 KIY70025.1 - 0.58 10.5 16.3 1.3 9.4 0.5 4.3 2 1 2 4 4 4 0 GAT domain DUF4407 PF14362.6 KIY70025.1 - 1.3 8.3 27.1 2.9 7.2 8.2 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4407) OmpH PF03938.14 KIY70025.1 - 1.7 9.0 37.5 2.9 8.2 12.7 3.5 1 1 1 3 3 3 0 Outer membrane protein (OmpH-like) IFT57 PF10498.9 KIY70025.1 - 1.7 7.5 28.8 1.1 8.2 9.5 3.3 1 1 2 3 3 3 0 Intra-flagellar transport protein 57 BLOC1_2 PF10046.9 KIY70025.1 - 1.7 9.0 26.0 1.2 9.5 0.1 4.8 1 1 4 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fez1 PF06818.15 KIY70025.1 - 2.7 8.4 35.9 7.6 6.9 13.5 2.6 1 1 1 2 2 2 0 Fez1 HrpB7 PF09486.10 KIY70025.1 - 6.6 7.1 37.5 0.51 10.7 6.1 3.3 1 1 3 4 4 4 0 Bacterial type III secretion protein (HrpB7) CENP-F_leu_zip PF10473.9 KIY70025.1 - 6.8 6.7 42.2 0.69 9.9 16.5 4.1 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Golgin_A5 PF09787.9 KIY70025.1 - 9.6 5.6 38.0 6 6.2 13.5 2.4 1 1 1 2 2 2 0 Golgin subfamily A member 5 Helicase_C PF00271.31 KIY70026.1 - 1.5e-19 70.4 0.0 3.6e-19 69.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KIY70026.1 - 9.3e-15 54.8 0.0 1.4e-14 54.2 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KIY70026.1 - 0.0026 17.8 0.0 0.0041 17.1 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DASH_Hsk3 PF08227.11 KIY70026.1 - 0.074 13.4 0.4 0.67 10.4 0.1 2.4 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like SWI2_SNF2 PF18766.1 KIY70026.1 - 0.089 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 SWI2/SNF2 ATPase SecA_DEAD PF07517.14 KIY70026.1 - 0.11 11.8 0.0 0.28 10.4 0.0 1.6 1 1 0 1 1 1 0 SecA DEAD-like domain GalP_UDP_transf PF01087.22 KIY70028.1 - 1.1e-57 195.5 0.0 2.1e-57 194.5 0.0 1.5 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 KIY70028.1 - 2.7e-49 167.1 0.0 2e-48 164.3 0.0 2.0 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain DcpS_C PF11969.8 KIY70028.1 - 0.014 15.8 0.6 0.043 14.3 0.6 1.7 1 1 0 1 1 1 0 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 KIY70028.1 - 0.016 15.9 0.4 0.1 13.4 0.7 2.2 2 1 0 2 2 2 0 HIT domain DUF3721 PF12518.8 KIY70028.1 - 0.6 10.0 2.4 6.6 6.7 0.7 2.5 2 0 0 2 2 2 0 Protein of unknown function DEAD PF00270.29 KIY70029.1 - 4.3e-44 150.4 0.0 1.5e-43 148.6 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIY70029.1 - 9.6e-26 90.3 0.0 6.7e-25 87.6 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIY70029.1 - 2e-05 24.7 0.0 0.00091 19.3 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-CCHC_4 PF14392.6 KIY70029.1 - 0.016 14.9 1.1 0.035 13.8 1.1 1.6 1 0 0 1 1 1 0 Zinc knuckle ERCC3_RAD25_C PF16203.5 KIY70029.1 - 0.025 13.8 0.0 0.025 13.8 0.0 1.9 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase zf-CCHC PF00098.23 KIY70029.1 - 0.04 14.0 1.3 0.073 13.2 1.3 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 KIY70029.1 - 0.042 13.7 1.2 0.082 12.7 1.2 1.5 1 0 0 1 1 1 0 Zinc knuckle F-box-like PF12937.7 KIY70030.1 - 1.5e-07 31.2 0.9 4.7e-07 29.6 0.9 2.0 1 0 0 1 1 1 1 F-box-like RapA_C PF12137.8 KIY70030.1 - 0.13 11.3 0.1 0.18 10.8 0.1 1.2 1 0 0 1 1 1 0 RNA polymerase recycling family C-terminal F-box PF00646.33 KIY70030.1 - 0.62 10.0 5.5 17 5.4 5.5 3.0 1 1 0 1 1 1 0 F-box domain Zn_clus PF00172.18 KIY70031.1 - 1.7e-07 31.2 12.9 1.7e-07 31.2 12.9 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AF-4 PF05110.13 KIY70034.1 - 1.2 7.1 6.2 1.5 6.8 6.2 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein COG4 PF08318.12 KIY70035.1 - 1.2e-94 317.2 0.0 1.8e-94 316.6 0.0 1.3 1 0 0 1 1 1 1 COG4 transport protein RINT1_TIP1 PF04437.13 KIY70035.1 - 0.00057 18.9 0.4 0.0012 17.9 0.4 1.6 1 1 0 1 1 1 1 RINT-1 / TIP-1 family AAA_assoc PF14363.6 KIY70035.1 - 0.0034 17.7 0.2 0.015 15.6 0.0 2.2 2 0 0 2 2 2 1 Domain associated at C-terminal with AAA SKA2 PF16740.5 KIY70035.1 - 0.043 13.6 0.4 0.92 9.3 0.1 3.0 1 1 0 2 2 2 0 Spindle and kinetochore-associated protein 2 Pkip-1 PF06878.11 KIY70035.1 - 0.11 12.6 0.2 0.38 10.8 0.1 2.0 2 0 0 2 2 2 0 Pkip-1 protein JIP_LZII PF16471.5 KIY70035.1 - 0.11 12.7 0.7 1.7 8.9 0.6 2.8 1 1 0 1 1 1 0 JNK-interacting protein leucine zipper II FUSC PF04632.12 KIY70035.1 - 0.81 8.1 6.6 0.17 10.4 2.3 1.9 2 0 0 2 2 2 0 Fusaric acid resistance protein family FliT PF05400.13 KIY70035.1 - 8.6 7.3 9.2 0.37 11.6 0.7 3.0 3 0 0 3 3 3 0 Flagellar protein FliT AHH PF14412.6 KIY70036.1 - 0.62 10.1 2.4 1.6 8.8 0.0 2.2 2 0 0 2 2 2 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH rRNA_proc-arch PF13234.6 KIY70037.1 - 9.6e-85 284.8 0.0 2.2e-84 283.6 0.0 1.6 2 0 0 2 2 2 1 rRNA-processing arch domain DSHCT PF08148.12 KIY70037.1 - 3.5e-54 182.9 0.4 9.6e-54 181.5 0.4 1.8 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 KIY70037.1 - 6.3e-18 65.1 0.1 3.2e-17 62.9 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIY70037.1 - 7.2e-07 29.5 0.0 2.8e-06 27.6 0.0 2.1 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIY70037.1 - 0.00036 20.6 0.0 0.0012 18.9 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 KIY70037.1 - 0.0034 16.5 0.0 0.02 14.0 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_22 PF13401.6 KIY70037.1 - 0.13 12.5 0.0 0.47 10.7 0.0 2.0 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.25 KIY70038.1 - 1.9e-53 181.6 0.1 2.7e-53 181.0 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY70038.1 - 1e-18 67.5 0.1 1.8e-18 66.8 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KIY70038.1 - 0.01 15.8 0.0 0.022 14.7 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 KIY70038.1 - 0.054 13.1 0.3 0.12 12.0 0.3 1.5 1 0 0 1 1 1 0 RIO1 family ABC1 PF03109.16 KIY70038.1 - 0.15 12.2 0.0 0.32 11.1 0.0 1.4 1 0 0 1 1 1 0 ABC1 family MINDY_DUB PF04424.13 KIY70040.1 - 4.2e-28 97.7 0.0 1.1e-27 96.3 0.0 1.7 2 0 0 2 2 2 1 MINDY deubiquitinase Pertussis_S1 PF02917.14 KIY70040.1 - 0.04 13.7 0.0 0.065 13.0 0.0 1.3 1 0 0 1 1 1 0 Pertussis toxin, subunit 1 Glyco_hydro_18 PF00704.28 KIY70041.1 - 3.8e-75 253.5 9.3 3.8e-75 253.5 9.3 1.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 CBM_5_12 PF02839.14 KIY70041.1 - 0.0006 20.3 5.7 0.0021 18.6 5.7 2.0 1 0 0 1 1 1 1 Carbohydrate binding domain Laminin_B PF00052.18 KIY70041.1 - 0.097 12.6 0.1 0.17 11.8 0.1 1.4 1 0 0 1 1 1 0 Laminin B (Domain IV) PPR_2 PF13041.6 KIY70043.1 - 0.0067 16.6 0.0 0.033 14.4 0.0 2.3 2 1 0 2 2 2 1 PPR repeat family Methyltransf_16 PF10294.9 KIY70044.1 - 7.9e-19 68.0 0.0 9.1e-19 67.8 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 KIY70044.1 - 0.013 14.9 0.1 0.019 14.3 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) GidB PF02527.15 KIY70044.1 - 0.086 12.2 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G TPR_10 PF13374.6 KIY70045.1 - 2.1e-38 129.1 21.0 8.9e-06 25.4 0.4 7.9 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_12 PF13424.6 KIY70045.1 - 4.4e-33 113.4 23.2 1.9e-09 37.6 3.0 6.9 2 1 4 7 7 7 6 Tetratricopeptide repeat NACHT PF05729.12 KIY70045.1 - 0.00014 21.9 0.0 0.00029 20.8 0.0 1.6 1 0 0 1 1 1 1 NACHT domain TPR_19 PF14559.6 KIY70045.1 - 0.00026 21.4 14.1 0.33 11.5 0.0 5.5 6 0 0 6 6 5 2 Tetratricopeptide repeat AAA_30 PF13604.6 KIY70045.1 - 0.0014 18.4 0.8 0.0099 15.6 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 KIY70045.1 - 0.0032 17.9 0.1 0.019 15.4 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain ATPase PF06745.13 KIY70045.1 - 0.0034 16.8 0.0 0.011 15.1 0.0 1.8 1 0 0 1 1 1 1 KaiC AAA_19 PF13245.6 KIY70045.1 - 0.0035 17.7 0.0 0.017 15.5 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KIY70045.1 - 0.0088 16.3 0.0 0.053 13.8 0.0 2.4 3 0 0 3 3 3 1 AAA domain NB-ARC PF00931.22 KIY70045.1 - 0.0096 15.1 0.0 0.033 13.4 0.0 1.8 1 1 0 1 1 1 1 NB-ARC domain DUF2075 PF09848.9 KIY70045.1 - 0.023 14.0 0.0 0.041 13.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 KIY70045.1 - 0.11 12.6 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_14 PF13173.6 KIY70045.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KIY70045.1 - 0.12 12.2 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain TPR_16 PF13432.6 KIY70045.1 - 0.23 12.1 27.7 2.7 8.7 3.2 6.4 4 1 2 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 KIY70045.1 - 9.2 6.8 9.9 20 5.7 0.1 4.1 4 0 0 4 4 3 0 Tetratricopeptide repeat HAMP PF00672.25 KIY70046.1 - 1.1e-44 150.6 24.1 2.7e-07 30.9 0.4 9.1 7 2 1 8 8 8 7 HAMP domain HATPase_c PF02518.26 KIY70046.1 - 6.6e-30 103.9 0.1 2.7e-29 102.0 0.1 2.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KIY70046.1 - 2.4e-23 82.4 0.8 6e-23 81.1 0.1 2.1 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 KIY70046.1 - 3.2e-17 62.3 0.6 1.8e-16 59.9 0.6 2.5 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain DUF3829 PF12889.7 KIY70046.1 - 0.00016 21.3 2.9 1.6 8.1 0.0 4.3 4 2 0 5 5 5 2 Protein of unknown function (DUF3829) APG17 PF04108.12 KIY70046.1 - 0.00025 20.3 0.2 2.9 6.9 0.4 3.7 2 1 3 5 5 5 3 Autophagy protein Apg17 DUF1843 PF08898.10 KIY70046.1 - 0.016 15.7 5.8 65 4.1 0.0 6.3 6 1 0 6 6 6 0 Domain of unknown function (DUF1843) HATPase_c_3 PF13589.6 KIY70046.1 - 0.058 13.2 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF4279 PF14106.6 KIY70046.1 - 0.11 12.7 0.0 28 4.9 0.0 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4279) T4SS PF07996.11 KIY70046.1 - 0.2 12.0 7.2 12 6.3 0.2 4.1 4 0 0 4 4 4 0 Type IV secretion system proteins CENP-F_leu_zip PF10473.9 KIY70046.1 - 0.62 10.1 9.1 24 4.9 0.3 5.3 5 1 0 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF948 PF06103.11 KIY70046.1 - 1.6 9.0 44.8 6.8 7.0 4.7 9.7 1 1 5 6 6 6 0 Bacterial protein of unknown function (DUF948) CPL PF08144.11 KIY70047.1 - 1.3e-38 132.6 0.1 4.7e-35 121.0 0.0 3.9 4 0 0 4 4 4 3 CPL (NUC119) domain Acid_PPase PF12689.7 KIY70048.1 - 1.3e-64 217.1 0.0 1.4e-64 217.0 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase Hydrolase PF00702.26 KIY70048.1 - 0.096 13.0 0.0 1.2 9.3 0.0 2.0 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase PHD PF00628.29 KIY70049.1 - 7.1e-06 25.8 10.5 1.1e-05 25.2 10.5 1.3 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KIY70049.1 - 0.014 14.9 3.1 0.025 14.1 3.1 1.4 1 0 0 1 1 1 0 PHD-finger ING PF12998.7 KIY70049.1 - 0.059 14.0 0.0 0.084 13.5 0.0 1.2 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding zf-HC5HC2H PF13771.6 KIY70049.1 - 0.15 12.3 8.3 0.048 13.9 2.7 2.1 1 1 1 2 2 2 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 KIY70049.1 - 0.17 12.1 6.0 0.15 12.2 2.2 2.1 1 1 1 2 2 2 0 PHD-zinc-finger like domain F-box-like PF12937.7 KIY70050.1 - 1.3e-05 25.0 0.7 3.4e-05 23.7 0.7 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY70050.1 - 0.025 14.5 3.0 3.7 7.6 0.3 2.8 2 0 0 2 2 2 0 F-box domain DUF913 PF06025.12 KIY70050.1 - 0.051 12.6 0.3 0.077 12.0 0.3 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RNA_pol_Rpc4 PF05132.14 KIY70050.1 - 0.26 11.7 1.4 0.45 10.9 1.4 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 Mpp10 PF04006.12 KIY70050.1 - 0.67 8.3 28.5 0.93 7.9 28.5 1.1 1 0 0 1 1 1 0 Mpp10 protein SAPS PF04499.15 KIY70050.1 - 1.1 8.0 5.9 1.6 7.4 5.9 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF2457 PF10446.9 KIY70050.1 - 1.6 7.8 41.6 2.5 7.2 41.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CDC45 PF02724.14 KIY70050.1 - 1.6 6.9 21.1 2.6 6.2 21.1 1.2 1 0 0 1 1 1 0 CDC45-like protein F-box-like PF12937.7 KIY70051.1 - 4.7e-06 26.4 0.3 1.2e-05 25.1 0.3 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY70051.1 - 0.77 9.7 5.4 3.7 7.5 0.1 3.0 3 0 0 3 3 3 0 F-box domain SlyX PF04102.12 KIY70051.1 - 1.4 9.6 4.2 3.9 8.1 4.2 1.7 1 0 0 1 1 1 0 SlyX F-box-like PF12937.7 KIY70052.1 - 3.5e-07 30.0 0.0 1e-06 28.5 0.0 1.9 1 1 0 1 1 1 1 F-box-like ATG16 PF08614.11 KIY70052.1 - 0.039 14.2 2.5 0.059 13.6 2.5 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) PUFD PF16553.5 KIY70052.1 - 0.15 12.2 0.2 1.2 9.3 0.0 2.6 4 0 0 4 4 4 0 BCORL-PCGF1-binding domain F-box PF00646.33 KIY70052.1 - 0.18 11.7 3.9 6.6 6.7 0.0 3.0 3 0 0 3 3 3 0 F-box domain RNase_PH PF01138.21 KIY70053.1 - 3.2e-18 66.5 0.0 5e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KIY70053.1 - 2.5e-08 33.8 0.0 4.6e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Trm112p PF03966.16 KIY70054.1 - 3.7e-20 72.3 0.5 6.7e-20 71.4 0.5 1.4 1 1 0 1 1 1 1 Trm112p-like protein Pan3_PK PF18101.1 KIY70055.1 - 2e-63 212.5 0.1 2.9e-63 211.9 0.1 1.3 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 KIY70055.1 - 0.001 18.5 0.0 0.003 17.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY70055.1 - 0.027 13.7 0.0 0.066 12.5 0.0 1.6 2 0 0 2 2 2 0 Protein tyrosine kinase TFA2_Winged_2 PF18121.1 KIY70056.1 - 8.8e-20 70.2 0.1 2e-19 69.0 0.1 1.7 1 0 0 1 1 1 1 TFA2 Winged helix domain 2 TFIIE_beta PF02186.15 KIY70056.1 - 1.7e-16 60.2 1.2 5.5e-16 58.6 0.8 2.0 2 0 0 2 2 2 1 TFIIE beta subunit core domain DUF903 PF06004.12 KIY70056.1 - 0.024 14.5 0.1 0.058 13.3 0.1 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF903) Methyltransf_31 PF13847.6 KIY70056.1 - 0.036 13.8 0.0 0.058 13.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF3293 PF11697.8 KIY70056.1 - 0.089 13.3 0.0 0.3 11.6 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3293) F-box-like PF12937.7 KIY70059.1 - 7.3e-06 25.8 0.0 2e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KIY70059.1 - 4.1 8.0 6.2 3.9 8.0 0.1 3.6 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) Glyco_transf_20 PF00982.21 KIY70060.1 - 2e-128 429.1 0.0 3e-128 428.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 KIY70060.1 - 2.1e-20 72.9 0.0 4e-20 71.9 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase Ldh_1_N PF00056.23 KIY70062.1 - 7.3e-48 162.2 0.1 1.8e-47 161.0 0.0 1.6 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 KIY70062.1 - 2.5e-44 151.1 0.0 3.5e-44 150.7 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.19 KIY70062.1 - 0.0042 16.1 0.0 0.0057 15.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family PEP_hydrolase PF09370.10 KIY70062.1 - 0.029 13.6 0.0 1.8 7.7 0.0 2.2 2 0 0 2 2 2 0 Phosphoenolpyruvate hydrolase-like Glyco_hydro_4 PF02056.16 KIY70062.1 - 0.03 13.9 0.1 0.15 11.6 0.1 2.1 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase STb_secrete PF09075.10 KIY70062.1 - 0.18 11.9 0.0 3.3 7.9 0.0 2.4 2 0 0 2 2 2 0 Heat-stable enterotoxin B, secretory THF_DHG_CYH_C PF02882.19 KIY70062.1 - 0.44 9.8 2.9 3 7.2 0.1 2.9 1 1 1 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain AA_permease_2 PF13520.6 KIY70063.1 - 2.6e-53 181.4 42.2 3.2e-53 181.1 42.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KIY70063.1 - 3.1e-20 72.2 33.7 4.2e-20 71.8 33.7 1.2 1 0 0 1 1 1 1 Amino acid permease Phage_holin_5_1 PF06946.11 KIY70063.1 - 0.0029 17.9 1.1 0.012 15.9 0.7 2.4 1 1 0 1 1 1 1 Bacteriophage A118-like holin, Hol118 AAA_12 PF13087.6 KIY70065.1 - 1.4e-41 142.4 0.0 2.4e-41 141.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KIY70065.1 - 2e-27 96.7 0.1 4.1e-17 62.8 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KIY70065.1 - 1.9e-10 41.3 0.0 1.4e-09 38.4 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KIY70065.1 - 4.3e-08 33.1 0.0 5.4e-07 29.5 0.0 2.5 1 1 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 KIY70065.1 - 4.6e-05 23.4 0.0 0.0013 18.6 0.0 2.8 3 0 0 3 3 3 1 Helicase UvrD-helicase PF00580.21 KIY70065.1 - 0.00016 21.3 0.0 0.00037 20.1 0.0 1.6 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain ResIII PF04851.15 KIY70065.1 - 0.0013 18.8 0.0 0.0022 18.0 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 KIY70065.1 - 0.0018 18.1 0.0 2.4 7.8 0.0 3.2 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 KIY70065.1 - 0.012 15.9 0.0 0.027 14.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain UvrD_C_2 PF13538.6 KIY70065.1 - 0.019 14.8 0.0 0.045 13.6 0.0 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain UvrD_C PF13361.6 KIY70065.1 - 0.042 13.2 0.0 0.41 10.0 0.1 2.0 1 1 1 2 2 2 0 UvrD-like helicase C-terminal domain AAA_16 PF13191.6 KIY70065.1 - 0.042 14.2 0.0 0.094 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain DUF3850 PF12961.7 KIY70065.1 - 0.091 12.8 0.0 0.51 10.4 0.0 2.2 3 0 0 3 3 2 0 Domain of unknown function (DUF3850) AAA_5 PF07728.14 KIY70065.1 - 0.098 12.7 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF2075 PF09848.9 KIY70065.1 - 0.11 11.7 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Tropomyosin_1 PF12718.7 KIY70066.1 - 0.0021 18.2 13.0 0.052 13.7 3.7 3.0 2 1 0 2 2 2 2 Tropomyosin like Methyltransf_25 PF13649.6 KIY70066.1 - 0.025 15.3 0.1 0.049 14.3 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain Trimer_CC PF08954.11 KIY70066.1 - 2 8.0 7.4 7.4 6.2 0.2 3.7 3 1 0 3 3 3 0 Trimerisation motif DEAD PF00270.29 KIY70067.1 - 1.7e-19 70.3 0.0 2e-17 63.5 0.0 2.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIY70067.1 - 4.6e-14 52.7 0.0 1.2e-13 51.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIY70067.1 - 0.0024 17.9 0.0 0.0064 16.5 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit GNAT_like PF18407.1 KIY70068.1 - 0.32 11.4 2.4 0.32 11.4 0.2 2.1 2 0 0 2 2 2 0 GCN5-related N-acetyltransferase like domain Baculo_PEP_C PF04513.12 KIY70068.1 - 6.3 6.8 8.3 3.6e+02 1.1 8.2 3.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus F-box-like PF12937.7 KIY70070.1 - 2.6e-06 27.2 0.0 7.2e-06 25.8 0.0 1.8 1 0 0 1 1 1 1 F-box-like Cyt-b5 PF00173.28 KIY70072.1 - 1.6e-13 50.6 0.0 2.1e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain bZIP_1 PF00170.21 KIY70073.1 - 2.3e-06 27.6 5.0 2.3e-06 27.6 5.0 1.7 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 KIY70073.1 - 0.00022 21.2 10.2 0.00053 20.0 10.2 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KIY70073.1 - 0.0054 17.2 4.0 0.0054 17.2 4.0 1.5 2 0 0 2 2 2 1 bZIP Maf transcription factor F-box-like PF12937.7 KIY70075.1 - 3.6e-08 33.2 2.3 1.2e-07 31.5 2.3 1.8 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KIY70075.1 - 0.0038 17.1 1.2 0.96 9.4 0.1 2.3 2 0 0 2 2 2 2 F-box domain PI3K_P85_iSH2 PF16454.5 KIY70075.1 - 0.15 11.6 0.1 0.2 11.2 0.1 1.2 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain HMG_box PF00505.19 KIY70076.1 - 6.9e-17 61.6 4.1 8.4e-17 61.4 4.1 1.1 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KIY70076.1 - 1.5e-12 47.9 2.4 1.7e-12 47.8 2.4 1.0 1 0 0 1 1 1 1 HMG-box domain Carbpep_Y_N PF05388.11 KIY70076.1 - 0.015 15.8 0.3 0.018 15.6 0.3 1.2 1 0 0 1 1 1 0 Carboxypeptidase Y pro-peptide SAP30_Sin3_bdg PF13867.6 KIY70076.1 - 0.071 13.5 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 Sin3 binding region of histone deacetylase complex subunit SAP30 AIG2_2 PF13772.6 KIY70077.1 - 5.3e-05 23.5 0.5 0.0016 18.8 0.3 2.6 2 1 0 2 2 2 1 AIG2-like family GGACT PF06094.12 KIY70077.1 - 0.00095 19.8 0.0 0.0014 19.2 0.0 1.4 1 1 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like HCNGP PF07818.13 KIY70078.1 - 3.3e-30 104.6 0.6 3.3e-30 104.6 0.6 1.8 2 0 0 2 2 2 1 HCNGP-like protein ABC_tran PF00005.27 KIY70079.1 - 1.6e-46 158.2 0.0 6.6e-29 101.2 0.1 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KIY70079.1 - 8.2e-46 156.9 24.8 7e-24 84.9 7.0 2.8 2 1 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 KIY70079.1 - 7.5e-11 41.9 6.3 0.0047 16.4 3.6 4.2 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KIY70079.1 - 1.5e-06 28.7 0.3 0.095 13.1 0.2 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 KIY70079.1 - 2.1e-06 27.8 3.4 0.064 13.1 0.4 4.2 3 1 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system T2SSE PF00437.20 KIY70079.1 - 5.3e-05 22.4 0.5 0.071 12.2 0.1 2.8 3 0 0 3 3 3 2 Type II/IV secretion system protein MMR_HSR1 PF01926.23 KIY70079.1 - 7.3e-05 22.8 0.0 0.12 12.4 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_25 PF13481.6 KIY70079.1 - 8.2e-05 22.3 0.0 0.29 10.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KIY70079.1 - 0.00018 21.2 2.4 0.39 10.5 0.1 3.1 3 0 0 3 3 3 2 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 KIY70079.1 - 0.00058 19.3 0.4 0.07 12.5 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_23 PF13476.6 KIY70079.1 - 0.0012 19.4 2.1 0.067 13.7 0.1 3.0 3 0 0 3 3 3 1 AAA domain DUF87 PF01935.17 KIY70079.1 - 0.0041 17.2 2.2 0.35 10.9 0.2 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_7 PF12775.7 KIY70079.1 - 0.0051 16.3 0.1 3.9 6.9 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region RsgA_GTPase PF03193.16 KIY70079.1 - 0.0095 15.8 0.2 3.9 7.3 0.0 2.7 3 0 0 3 3 3 1 RsgA GTPase DEAD PF00270.29 KIY70079.1 - 0.057 13.2 0.8 7 6.4 0.4 2.9 2 1 0 2 2 2 0 DEAD/DEAH box helicase Dynamin_N PF00350.23 KIY70079.1 - 0.065 13.3 5.4 0.66 10.0 0.1 3.0 3 0 0 3 3 3 0 Dynamin family Adeno_IVa2 PF02456.15 KIY70079.1 - 0.087 11.6 0.2 2.7 6.7 0.0 2.7 3 0 0 3 3 3 0 Adenovirus IVa2 protein AAA_22 PF13401.6 KIY70079.1 - 0.099 12.9 2.5 13 6.1 0.0 3.2 2 1 0 2 2 2 0 AAA domain AAA PF00004.29 KIY70079.1 - 0.13 12.7 1.1 13 6.2 0.0 3.0 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) DnaB_bind PF10410.9 KIY70079.1 - 0.13 12.4 0.0 0.42 10.8 0.0 1.8 1 0 0 1 1 1 0 DnaB-helicase binding domain of primase TrwB_AAD_bind PF10412.9 KIY70079.1 - 0.14 11.1 0.4 6.5 5.6 0.1 2.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Zeta_toxin PF06414.12 KIY70079.1 - 0.17 11.2 0.1 4.8 6.4 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin DUF2976 PF11190.8 KIY70079.1 - 0.17 11.7 2.0 8.1 6.3 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2976) IstB_IS21 PF01695.17 KIY70079.1 - 0.17 11.6 2.5 8 6.1 0.0 3.2 3 0 0 3 3 3 0 IstB-like ATP binding protein cobW PF02492.19 KIY70079.1 - 0.19 11.3 0.6 3.3 7.2 0.2 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.14 KIY70079.1 - 0.2 11.7 0.9 39 4.2 0.0 3.3 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) ResIII PF04851.15 KIY70079.1 - 0.22 11.5 0.2 11 6.0 0.0 3.0 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit AAA_15 PF13175.6 KIY70079.1 - 0.24 11.1 0.9 1.7 8.3 0.0 2.4 3 0 0 3 3 2 0 AAA ATPase domain AAA_30 PF13604.6 KIY70079.1 - 0.28 10.9 1.3 8.4 6.1 0.0 2.9 3 0 0 3 3 3 0 AAA domain Pox_A32 PF04665.12 KIY70079.1 - 6.9 6.0 5.3 12 5.3 0.1 2.5 3 0 0 3 3 2 0 Poxvirus A32 protein F-box-like PF12937.7 KIY70080.1 - 0.00012 21.8 0.0 0.00045 20.1 0.0 2.1 2 1 0 2 2 2 1 F-box-like LRR_4 PF12799.7 KIY70080.1 - 0.051 14.0 0.2 78 3.9 0.1 4.5 5 1 0 5 5 5 0 Leucine Rich repeats (2 copies) TEA PF01285.18 KIY70081.1 - 6e-21 74.3 0.1 9.9e-21 73.6 0.1 1.4 1 0 0 1 1 1 1 TEA/ATTS domain DMRL_synthase PF00885.19 KIY70082.1 - 2.7e-56 189.3 0.0 4e-56 188.8 0.0 1.3 1 1 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase BTB PF00651.31 KIY70083.1 - 6.7e-05 23.1 0.0 0.00014 22.1 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain LppA PF16708.5 KIY70083.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Lipoprotein confined to pathogenic Mycobacterium Peroxidase_2 PF01328.17 KIY70084.1 - 1.6e-48 165.7 0.0 1.9e-48 165.5 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 LRR_10 PF18805.1 KIY70084.1 - 0.087 12.5 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Leucine-rich repeat RabGAP-TBC PF00566.18 KIY70085.1 - 6e-11 42.4 0.0 1.3e-10 41.3 0.0 1.6 2 0 0 2 2 2 1 Rab-GTPase-TBC domain TilS_C PF11734.8 KIY70085.1 - 0.038 13.4 0.2 0.13 11.7 0.1 1.8 2 0 0 2 2 2 0 TilS substrate C-terminal domain SH3_2 PF07653.17 KIY70086.1 - 0.00011 21.8 0.0 0.00015 21.4 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain ArsA_ATPase PF02374.15 KIY70086.1 - 0.035 13.3 0.0 0.039 13.1 0.0 1.1 1 0 0 1 1 1 0 Anion-transporting ATPase Epimerase PF01370.21 KIY70087.1 - 1.2e-20 74.1 0.1 1.7e-20 73.5 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KIY70087.1 - 1.2e-13 51.4 0.2 2.4e-13 50.4 0.2 1.6 1 1 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KIY70087.1 - 4.1e-09 35.8 0.0 5.6e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KIY70087.1 - 2.6e-08 33.7 0.0 3.2e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KIY70087.1 - 3.6e-06 26.7 0.1 6.1e-06 26.0 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 KIY70087.1 - 5.7e-05 22.4 0.0 0.21 10.7 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein adh_short PF00106.25 KIY70087.1 - 0.029 13.8 0.1 0.056 12.9 0.1 1.5 1 0 0 1 1 1 0 short chain dehydrogenase Beta-lactamase PF00144.24 KIY70088.1 - 5.5e-33 114.6 1.9 8.9e-33 113.9 1.9 1.2 1 0 0 1 1 1 1 Beta-lactamase GrlR PF16518.5 KIY70088.1 - 0.098 12.6 0.1 0.24 11.4 0.1 1.7 1 1 0 1 1 1 0 T3SS negative regulator,GrlR PQQ_3 PF13570.6 KIY70088.1 - 0.25 11.9 5.2 0.37 11.3 0.1 3.3 4 0 0 4 4 4 0 PQQ-like domain Fungal_trans PF04082.18 KIY70089.1 - 9.5e-15 54.3 0.0 3.8e-14 52.4 0.0 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY70089.1 - 2.2e-07 30.8 10.8 4.5e-07 29.9 10.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Flavin_Reduct PF01613.18 KIY70090.1 - 1.5e-32 112.8 0.2 1.8e-32 112.5 0.2 1.1 1 0 0 1 1 1 1 Flavin reductase like domain BTB PF00651.31 KIY70091.1 - 0.0018 18.5 0.0 0.0043 17.3 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain p450 PF00067.22 KIY70092.1 - 2.4e-58 198.0 0.0 2.9e-58 197.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF2183 PF09949.9 KIY70093.1 - 2.3e-26 92.0 0.0 5.5e-26 90.8 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) LNS2 PF08235.13 KIY70093.1 - 0.03 13.8 0.0 0.055 12.9 0.0 1.4 1 0 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) MBOAT_2 PF13813.6 KIY70094.1 - 2.4e-18 66.2 0.7 7.6e-18 64.6 0.7 1.9 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family PRK PF00485.18 KIY70095.1 - 1.4e-05 24.9 0.0 2e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 KIY70095.1 - 0.00068 20.2 0.0 0.002 18.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KIY70095.1 - 0.00083 19.5 0.0 0.0015 18.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 KIY70095.1 - 0.0042 16.6 0.0 0.0058 16.1 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 NB-ARC PF00931.22 KIY70095.1 - 0.089 12.0 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_17 PF13207.6 KIY70095.1 - 0.14 12.6 0.0 0.68 10.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 KIY70095.1 - 0.14 11.1 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF98 PF01947.16 KIY70096.1 - 0.0034 17.4 0.0 0.0046 16.9 0.0 1.2 1 0 0 1 1 1 1 p-hydroxybenzoic acid synthase SIR2 PF02146.17 KIY70097.1 - 6.7e-62 208.5 0.0 1.2e-61 207.7 0.0 1.4 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.13 KIY70097.1 - 7.1e-06 25.9 0.1 2.1e-05 24.3 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.22 KIY70097.1 - 0.00025 20.8 0.2 0.21 11.3 0.0 2.4 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain Paired_CXXCH_1 PF09699.10 KIY70097.1 - 0.0082 15.9 3.0 0.026 14.3 2.6 2.2 2 0 0 2 2 2 1 Doubled CXXCH motif (Paired_CXXCH_1) Cytochrom_CIII PF02085.16 KIY70097.1 - 0.026 14.9 2.7 0.052 13.9 2.7 1.4 1 0 0 1 1 1 0 Class III cytochrome C family CutC PF03932.14 KIY70097.1 - 0.11 12.0 0.0 0.26 10.7 0.0 1.6 2 0 0 2 2 2 0 CutC family Cytochrom_c3_2 PF14537.6 KIY70097.1 - 1.3 9.6 5.7 3.9 8.0 5.8 1.8 1 1 1 2 2 2 0 Cytochrome c3 Cytochrome_C7 PF14522.6 KIY70097.1 - 8.3 6.5 8.9 15 5.7 0.6 2.4 1 1 2 3 3 3 0 Cytochrome c7 and related cytochrome c DUF952 PF06108.12 KIY70099.1 - 2.2e-16 59.6 0.0 3.1e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF952) zf-RING_UBOX PF13445.6 KIY70100.1 - 9.6e-08 31.9 3.0 2.6e-07 30.5 3.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KIY70100.1 - 1.4e-07 31.2 2.3 1.4e-07 31.2 2.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIY70100.1 - 4.7e-06 26.4 5.7 1.7e-05 24.6 5.7 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KIY70100.1 - 8.8e-06 25.5 8.2 7.7e-05 22.5 1.4 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIY70100.1 - 1.2e-05 25.5 1.9 1.2e-05 25.5 1.9 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.6 KIY70100.1 - 3.8e-05 23.8 3.5 3.8e-05 23.8 3.5 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 KIY70100.1 - 3.8e-05 23.5 6.5 8.9e-05 22.4 6.5 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_6 PF14835.6 KIY70100.1 - 0.0014 18.5 0.2 0.0035 17.2 0.2 1.7 1 0 0 1 1 1 1 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 KIY70100.1 - 0.0021 17.9 2.3 0.0021 17.9 2.3 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 KIY70100.1 - 0.014 15.0 0.4 0.014 15.0 0.4 1.9 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_10 PF16685.5 KIY70100.1 - 0.044 13.9 2.0 0.099 12.8 2.0 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-rbx1 PF12678.7 KIY70100.1 - 0.77 10.1 7.3 4.2 7.7 7.3 2.1 1 1 0 1 1 1 0 RING-H2 zinc finger domain Atg14 PF10186.9 KIY70100.1 - 1.3 8.1 12.1 2.4 7.1 12.1 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TMPIT PF07851.13 KIY70100.1 - 3.5 6.8 7.8 5.2 6.2 7.8 1.2 1 0 0 1 1 1 0 TMPIT-like protein ATG16 PF08614.11 KIY70100.1 - 4.4 7.5 22.8 0.088 13.0 14.9 1.9 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) zf-C2H2_8 PF15909.5 KIY70101.1 - 0.00043 20.5 5.3 0.0021 18.3 0.7 2.9 3 1 0 3 3 3 1 C2H2-type zinc ribbon zf-C2H2_4 PF13894.6 KIY70101.1 - 0.063 14.1 0.3 0.063 14.1 0.3 4.3 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KIY70101.1 - 0.7 10.5 22.0 0.57 10.8 0.5 4.4 4 0 0 4 4 4 0 Zinc finger, C2H2 type ATG101 PF07855.12 KIY70103.1 - 5.3e-36 123.9 0.1 5.9e-36 123.8 0.1 1.0 1 0 0 1 1 1 1 Autophagy-related protein 101 FAD_binding_3 PF01494.19 KIY70105.1 - 1.1e-21 77.4 0.0 1.4e-21 77.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 KIY70105.1 - 3.5e-07 29.7 0.0 4.3e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KIY70105.1 - 2.8e-05 23.5 0.5 0.00011 21.6 0.2 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIY70105.1 - 0.00015 22.0 0.9 0.00046 20.4 0.9 1.9 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.10 KIY70105.1 - 0.00025 20.2 0.0 0.00096 18.3 0.0 1.8 1 1 0 1 1 1 1 Squalene epoxidase GIDA PF01134.22 KIY70105.1 - 0.00046 19.4 0.2 0.00081 18.6 0.2 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KIY70105.1 - 0.00072 18.9 0.9 0.18 11.0 0.6 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIY70105.1 - 0.0032 17.1 1.7 0.0081 15.8 1.4 1.7 1 1 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KIY70105.1 - 0.0039 16.0 0.3 0.0067 15.2 0.3 1.5 1 1 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.7 KIY70105.1 - 0.01 15.2 0.7 0.021 14.2 0.7 1.6 1 1 0 1 1 1 0 FAD dependent oxidoreductase Amino_oxidase PF01593.24 KIY70105.1 - 0.011 15.0 0.1 0.94 8.7 0.0 2.5 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 KIY70105.1 - 0.13 12.9 0.4 0.35 11.4 0.4 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Gly-zipper_Omp PF13488.6 KIY70106.1 - 4.1 7.5 5.2 7.3 6.7 5.2 1.3 1 0 0 1 1 1 0 Glycine zipper GST_N_3 PF13417.6 KIY70107.1 - 5.2e-11 42.8 0.1 8.6e-11 42.1 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KIY70107.1 - 5.1e-08 33.1 0.0 1e-07 32.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KIY70107.1 - 1.3e-06 28.7 0.1 3.8e-06 27.2 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KIY70107.1 - 4.5e-06 26.6 0.4 8.5e-06 25.7 0.4 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KIY70107.1 - 6.2e-05 23.1 0.1 0.00058 20.0 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KIY70107.1 - 8.8e-05 23.0 0.0 0.00016 22.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KIY70107.1 - 0.00034 20.8 0.0 0.00059 20.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 KIY70107.1 - 0.0037 17.5 0.0 0.008 16.4 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin zf-MYND PF01753.18 KIY70108.1 - 3.2e-06 27.1 16.6 3.2e-06 27.1 16.6 2.6 2 0 0 2 2 2 1 MYND finger adh_short_C2 PF13561.6 KIY70109.1 - 1.7e-49 168.5 4.2 6.1e-49 166.7 4.2 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIY70109.1 - 6.3e-33 113.9 1.5 1.8e-32 112.4 1.5 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIY70109.1 - 0.00013 22.0 0.2 0.056 13.4 0.0 2.8 3 0 0 3 3 3 2 KR domain GATA PF00320.27 KIY70110.1 - 1.2e-13 50.3 2.5 2.9e-13 49.2 2.5 1.6 1 0 0 1 1 1 1 GATA zinc finger ERM PF00769.19 KIY70110.1 - 5.8e-05 23.0 12.6 7.9e-05 22.6 12.6 1.3 1 0 0 1 1 1 1 Ezrin/radixin/moesin family DUF4407 PF14362.6 KIY70110.1 - 0.27 10.6 8.6 0.35 10.2 8.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Borrelia_P83 PF05262.11 KIY70110.1 - 0.47 8.9 8.0 0.52 8.8 8.0 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Hid1 PF12722.7 KIY70110.1 - 1.1 7.3 2.6 1.4 7.0 2.6 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDC45 PF02724.14 KIY70110.1 - 1.9 6.7 9.6 2.8 6.1 9.6 1.2 1 0 0 1 1 1 0 CDC45-like protein OrfB_IS605 PF01385.19 KIY70110.1 - 4.7 7.5 11.8 4.8 7.4 10.4 1.7 1 1 0 1 1 1 0 Probable transposase DUF3527 PF12043.8 KIY70110.1 - 5.4 6.5 6.2 9.1 5.7 6.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3527) XRN_M PF17846.1 KIY70110.1 - 6 5.7 6.4 8.3 5.2 6.4 1.2 1 0 0 1 1 1 0 Xrn1 helical domain EthD PF07110.11 KIY70111.1 - 4.9e-14 53.3 0.8 5.8e-14 53.0 0.8 1.1 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 KIY70111.1 - 1.6e-06 28.6 0.0 2e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 Methylmuconolactone methyl-isomerase DUF3489 PF11994.8 KIY70111.1 - 0.14 12.2 0.0 0.3 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3489) Peroxidase_2 PF01328.17 KIY70112.1 - 1.6e-49 169.0 0.0 2e-49 168.6 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 LRR_10 PF18805.1 KIY70112.1 - 0.091 12.4 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Leucine-rich repeat zf-C2H2_4 PF13894.6 KIY70117.1 - 0.075 13.9 0.6 0.25 12.3 0.6 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger CLP1_N PF16573.5 KIY70120.1 - 4.5e-32 110.1 0.0 7.7e-32 109.4 0.0 1.4 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor CLP1_P PF16575.5 KIY70120.1 - 5.9e-32 111.0 0.0 3.4e-31 108.5 0.0 2.1 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Clp1 PF06807.14 KIY70120.1 - 8.5e-29 100.4 0.0 1.4e-28 99.6 0.0 1.4 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 ATP_bind_1 PF03029.17 KIY70120.1 - 0.0013 18.6 0.0 0.0022 17.8 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 KIY70120.1 - 0.0052 16.9 0.1 0.02 15.0 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase TniB PF05621.11 KIY70120.1 - 0.037 13.4 0.0 0.11 11.9 0.0 1.8 1 0 0 1 1 1 0 Bacterial TniB protein Roc PF08477.13 KIY70120.1 - 0.042 14.1 0.0 0.1 12.8 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KIY70120.1 - 0.046 13.1 0.0 0.22 11.0 0.0 1.9 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 KIY70120.1 - 0.077 12.7 0.1 2.2 8.0 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 KIY70120.1 - 0.12 12.8 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 KIY70120.1 - 0.13 11.9 0.2 0.32 10.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KIY70120.1 - 0.15 11.9 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea HMA PF00403.26 KIY70122.1 - 1.8e-09 37.9 0.5 3.4e-09 37.0 0.5 1.5 1 1 0 1 1 1 1 Heavy-metal-associated domain MBOAT_2 PF13813.6 KIY70124.1 - 2.6e-16 59.6 4.8 2.6e-16 59.6 4.8 1.9 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family Abhydrolase_9_N PF15420.6 KIY70124.1 - 0.019 15.0 1.1 0.019 15.0 1.1 2.1 2 1 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus DUF2304 PF10066.9 KIY70124.1 - 0.021 15.0 1.5 0.24 11.6 0.2 2.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) Adhesin_P1_N PF18652.1 KIY70126.1 - 0.36 10.9 3.7 2.7 8.0 1.3 3.2 2 1 1 3 3 3 0 Adhesin P1 N-terminal domain HD_3 PF13023.6 KIY70127.1 - 3e-42 144.3 1.6 3.5e-42 144.1 1.6 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 KIY70127.1 - 3.7e-10 39.8 0.4 5.2e-10 39.4 0.4 1.3 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 KIY70127.1 - 1.7e-07 31.5 0.1 2.6e-07 30.9 0.1 1.3 1 0 0 1 1 1 1 HD domain DUF3523 PF12037.8 KIY70127.1 - 0.12 11.7 0.3 0.17 11.2 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) RCC1 PF00415.18 KIY70128.1 - 2.9e-41 139.9 16.1 4.1e-12 46.5 0.1 6.9 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KIY70128.1 - 5e-24 83.5 17.5 2.8e-08 33.3 0.3 5.4 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat PHD PF00628.29 KIY70128.1 - 2.8e-10 39.9 5.8 2.8e-10 39.9 5.8 2.4 2 0 0 2 2 2 1 PHD-finger C1_1 PF00130.22 KIY70128.1 - 0.0021 17.9 0.3 0.0021 17.9 0.3 2.4 3 0 0 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 KIY70128.1 - 0.01 16.1 1.5 0.01 16.1 1.5 2.1 2 0 0 2 2 2 0 C1 domain Prok-RING_1 PF14446.6 KIY70128.1 - 0.022 14.7 2.2 0.022 14.7 2.2 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 TFIIA PF03153.13 KIY70128.1 - 0.033 14.2 25.1 0.042 13.8 25.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-rbx1 PF12678.7 KIY70128.1 - 0.34 11.2 6.1 0.72 10.2 3.9 2.4 2 0 0 2 2 2 0 RING-H2 zinc finger domain DZR PF12773.7 KIY70128.1 - 5.6 7.1 11.4 37 4.4 7.1 3.2 2 1 1 3 3 3 0 Double zinc ribbon zf-C2H2_4 PF13894.6 KIY70129.1 - 9.4e-05 22.9 2.1 0.07 14.0 0.1 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger IBR PF01485.21 KIY70129.1 - 0.0033 17.6 2.3 0.006 16.8 2.3 1.4 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain zf-H2C2_2 PF13465.6 KIY70129.1 - 0.0039 17.6 1.8 0.0049 17.2 0.3 2.1 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.26 KIY70129.1 - 0.017 15.5 3.2 1.5 9.4 0.2 3.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-TRAF PF02176.18 KIY70129.1 - 0.046 14.4 5.3 1.4 9.6 1.3 2.4 1 1 1 2 2 2 0 TRAF-type zinc finger zf-C2H2_11 PF16622.5 KIY70129.1 - 0.051 13.3 0.5 0.051 13.3 0.5 1.8 2 0 0 2 2 2 0 zinc-finger C2H2-type zinc_ribbon_4 PF13717.6 KIY70129.1 - 0.077 12.9 0.3 0.18 11.7 0.3 1.6 1 0 0 1 1 1 0 zinc-ribbon domain Macoilin PF09726.9 KIY70129.1 - 1.6 7.2 4.0 1.9 7.0 4.0 1.1 1 0 0 1 1 1 0 Macoilin family adh_short PF00106.25 KIY70130.1 - 2.7e-38 131.4 0.1 3.6e-38 131.0 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIY70130.1 - 1.4e-31 109.9 0.0 1.9e-31 109.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIY70130.1 - 3.3e-11 43.4 1.5 5.1e-10 39.6 1.2 2.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KIY70130.1 - 0.013 14.9 0.0 0.24 10.8 0.0 2.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KIY70130.1 - 0.02 14.8 0.0 0.43 10.4 0.0 2.1 1 1 0 1 1 1 0 NAD(P)H-binding YlzJ PF14035.6 KIY70131.1 - 0.13 12.5 0.1 0.41 10.9 0.0 1.8 2 0 0 2 2 2 0 YlzJ-like protein zf-C2H2_4 PF13894.6 KIY70131.1 - 0.88 10.6 7.9 10 7.3 0.1 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KIY70131.1 - 1.8 8.4 4.7 0.78 9.5 1.2 2.3 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-DNL PF05180.12 KIY70132.1 - 1.5e-31 108.1 0.5 1.9e-31 107.8 0.5 1.1 1 0 0 1 1 1 1 DNL zinc finger zinc_ribbon_4 PF13717.6 KIY70132.1 - 0.01 15.7 0.1 4.2 7.4 0.0 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Elf1 PF05129.13 KIY70132.1 - 0.019 15.0 0.8 0.03 14.3 0.8 1.2 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like SGL PF08450.12 KIY70133.1 - 2.8e-27 95.9 0.0 4.7e-27 95.1 0.0 1.4 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 KIY70133.1 - 0.0002 21.4 0.0 0.0014 18.7 0.0 2.2 1 1 0 1 1 1 1 Strictosidine synthase PD40 PF07676.12 KIY70133.1 - 0.035 14.0 0.0 0.089 12.8 0.0 1.7 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat Arylesterase PF01731.20 KIY70133.1 - 0.12 12.6 0.0 0.95 9.7 0.0 2.3 2 0 0 2 2 2 0 Arylesterase SoxE PF06525.11 KIY70133.1 - 0.13 11.7 0.0 0.44 10.0 0.0 1.8 1 1 1 2 2 2 0 Sulfocyanin (SoxE) domain 2-Hacid_dh_C PF02826.19 KIY70134.1 - 2.5e-45 154.0 0.0 3.5e-45 153.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KIY70134.1 - 8.6e-22 77.2 0.0 1.2e-21 76.8 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KIY70134.1 - 1.4e-06 28.6 0.0 3.6e-06 27.2 0.0 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AlaDh_PNT_C PF01262.21 KIY70134.1 - 0.0022 17.3 0.0 0.58 9.4 0.0 2.3 1 1 1 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 KIY70134.1 - 0.014 15.5 0.0 0.52 10.4 0.0 2.5 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DUF3884 PF13024.6 KIY70134.1 - 0.014 14.9 0.0 0.06 12.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3884) Chromo PF00385.24 KIY70136.1 - 2.2e-10 40.3 0.0 3.3e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.8 KIY70136.1 - 0.013 15.3 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain DUF960 PF06124.11 KIY70138.1 - 0.063 13.9 0.0 0.16 12.6 0.0 1.6 2 0 0 2 2 2 0 Staphylococcal protein of unknown function (DUF960) gag-asp_proteas PF13975.6 KIY70139.1 - 0.028 15.0 0.0 0.1 13.2 0.0 2.0 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Phage_rep_org_N PF09681.10 KIY70139.1 - 2.6 8.0 4.5 2.3 8.2 0.1 2.3 2 0 0 2 2 2 0 N-terminal phage replisome organiser (Phage_rep_org_N) Zn_clus PF00172.18 KIY70142.1 - 7e-07 29.3 8.1 1.3e-06 28.4 8.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TRAPPC-Trs85 PF12739.7 KIY70143.1 - 2.7e-35 122.1 0.0 1.3e-28 100.2 0.0 2.5 2 0 0 2 2 2 2 ER-Golgi trafficking TRAPP I complex 85 kDa subunit TRAPPC9-Trs120 PF08626.11 KIY70143.1 - 0.032 11.6 0.0 0.048 11.0 0.0 1.1 1 0 0 1 1 1 0 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Pep3_Vps18 PF05131.14 KIY70145.1 - 9e-49 165.1 0.0 1.8e-48 164.2 0.0 1.5 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 KIY70145.1 - 1.7e-10 40.9 0.0 2.8e-05 24.0 0.0 2.9 2 1 0 2 2 2 2 Region in Clathrin and VPS Vps39_2 PF10367.9 KIY70145.1 - 9.6e-06 26.0 0.0 2.9e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 zf-C3HC4_2 PF13923.6 KIY70145.1 - 0.00035 20.4 2.5 0.00035 20.4 2.5 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIY70145.1 - 0.0014 18.5 1.0 0.0014 18.5 1.0 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 KIY70145.1 - 0.0026 18.0 4.0 0.0027 18.0 0.9 2.4 2 0 0 2 2 2 1 Ring finger domain Zn_ribbon_17 PF17120.5 KIY70145.1 - 0.0036 16.9 1.8 0.011 15.4 1.8 1.7 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type TPR_2 PF07719.17 KIY70145.1 - 0.0062 16.6 3.4 1 9.6 0.1 3.0 1 1 1 2 2 2 2 Tetratricopeptide repeat zf-RING_UBOX PF13445.6 KIY70145.1 - 0.015 15.3 2.5 0.025 14.6 1.0 2.1 2 0 0 2 2 2 0 RING-type zinc-finger Zf_RING PF16744.5 KIY70145.1 - 0.061 13.4 0.3 0.15 12.2 0.3 1.6 1 0 0 1 1 1 0 KIAA1045 RING finger zf-RING_11 PF17123.5 KIY70145.1 - 0.073 12.8 9.6 0.022 14.5 5.8 2.2 2 0 0 2 2 2 0 RING-like zinc finger NopRA1 PF16201.5 KIY70145.1 - 0.077 12.6 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 Nucleolar pre-ribosomal-associated protein 1 TPR_1 PF00515.28 KIY70145.1 - 0.49 10.3 1.9 5 7.1 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Prok-RING_4 PF14447.6 KIY70145.1 - 1.8 8.5 6.1 17 5.4 0.0 2.7 3 0 0 3 3 2 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KIY70145.1 - 3.1 7.7 5.7 0.48 10.3 1.0 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Pkinase_Tyr PF07714.17 KIY70147.1 - 1e-40 139.7 0.0 4.4e-29 101.6 0.0 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KIY70147.1 - 1.3e-29 103.3 0.0 1.3e-23 83.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Kdo PF06293.14 KIY70147.1 - 0.006 16.0 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIY70147.1 - 0.012 15.5 0.0 0.028 14.3 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family CDC24 PF06395.11 KIY70147.1 - 0.013 15.7 0.0 0.09 13.0 0.0 2.1 1 1 0 1 1 1 0 CDC24 Calponin RIO1 PF01163.22 KIY70147.1 - 0.036 13.7 0.3 0.084 12.5 0.0 1.7 2 0 0 2 2 2 0 RIO1 family PH_10 PF15411.6 KIY70147.1 - 0.061 13.6 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain Seipin PF06775.14 KIY70148.1 - 5.2e-20 72.4 0.0 8.7e-19 68.4 0.0 2.0 1 1 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) Oxidored_FMN PF00724.20 KIY70149.1 - 4.3e-62 210.3 0.0 5.9e-62 209.9 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family 3HCDH_RFF PF18321.1 KIY70149.1 - 0.0018 18.7 0.7 0.0051 17.2 0.1 2.1 2 0 0 2 2 2 1 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain Dus PF01207.17 KIY70149.1 - 0.012 14.7 0.0 0.027 13.6 0.0 1.6 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) F-box-like PF12937.7 KIY70150.1 - 1.8e-06 27.7 4.1 3.9e-06 26.7 0.1 2.7 3 0 0 3 3 3 1 F-box-like LRR_4 PF12799.7 KIY70150.1 - 0.11 13.0 7.1 8.9 6.9 0.1 4.7 3 3 1 4 4 4 0 Leucine Rich repeats (2 copies) Longin_2 PF18639.1 KIY70150.1 - 0.13 12.1 0.0 0.62 9.9 0.0 1.9 2 0 0 2 2 2 0 Yeast longin domain DUF21 PF01595.20 KIY70151.1 - 1.2e-29 103.3 0.1 1.8e-29 102.7 0.1 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 KIY70151.1 - 0.00027 21.3 0.2 1.4 9.4 0.0 3.5 3 0 0 3 3 3 2 CBS domain LMWPc PF01451.21 KIY70152.1 - 2.9e-35 121.7 0.0 3.3e-35 121.6 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase SH3BGR PF04908.15 KIY70153.1 - 9.4e-11 41.8 0.0 2.7e-10 40.3 0.0 1.8 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Shisa PF13908.6 KIY70154.1 - 2.1 8.6 0.0 2.1 8.6 0.0 3.2 1 1 0 2 2 2 0 Wnt and FGF inhibitory regulator LapA_dom PF06305.11 KIY70155.1 - 0.023 14.5 0.1 0.045 13.6 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain TatD_DNase PF01026.21 KIY70156.1 - 6.5e-48 163.3 0.0 8e-48 163.0 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Thiolase_N PF00108.23 KIY70157.1 - 6.4e-72 242.0 0.1 9.5e-72 241.5 0.1 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KIY70157.1 - 2.9e-46 156.1 0.8 2.9e-46 156.1 0.8 2.0 3 0 0 3 3 3 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 KIY70157.1 - 0.0005 19.9 5.2 0.011 15.6 0.1 3.3 4 0 0 4 4 4 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 KIY70157.1 - 0.0018 17.9 2.0 0.0054 16.3 0.8 2.2 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.10 KIY70157.1 - 0.11 12.7 0.0 0.29 11.3 0.0 1.7 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal AJAP1_PANP_C PF15298.6 KIY70158.1 - 0.096 12.9 0.6 0.3 11.3 0.6 1.8 1 0 0 1 1 1 0 AJAP1/PANP C-terminus p450 PF00067.22 KIY70159.1 - 1.2e-39 136.3 0.0 1.4e-39 136.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short_C2 PF13561.6 KIY70160.1 - 1.2e-45 156.0 0.0 2.4e-45 154.9 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIY70160.1 - 6e-38 130.3 0.2 9.1e-38 129.7 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIY70160.1 - 5.7e-07 29.6 0.1 9.9e-07 28.8 0.1 1.4 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KIY70160.1 - 0.021 14.2 0.0 0.031 13.6 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Rav1p_C PF12234.8 KIY70161.1 - 1.2e-193 645.0 0.0 1.9e-193 644.4 0.0 1.2 1 0 0 1 1 1 1 RAVE protein 1 C terminal DAGAT PF03982.13 KIY70162.1 - 1e-98 330.0 0.0 1.3e-98 329.6 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Rer1 PF03248.13 KIY70162.1 - 0.083 12.6 2.1 0.18 11.6 2.1 1.5 1 0 0 1 1 1 0 Rer1 family SKN1 PF03935.15 KIY70163.1 - 3.9e-192 639.1 1.9 4.5e-192 638.9 1.9 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) SNAPc_SNAP43 PF09808.9 KIY70165.1 - 2.7e-05 24.2 0.0 3.7e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 Ima1_N PF09779.9 KIY70166.1 - 3.8e-30 105.5 4.6 6.6e-30 104.7 4.6 1.3 1 0 0 1 1 1 1 Ima1 N-terminal domain zinc_ribbon_9 PF14369.6 KIY70166.1 - 0.0017 18.5 14.8 0.018 15.3 4.2 3.4 3 0 0 3 3 3 1 zinc-ribbon Zn_Tnp_IS1595 PF12760.7 KIY70166.1 - 0.0046 16.9 3.0 0.014 15.4 0.1 2.9 3 0 0 3 3 3 1 Transposase zinc-ribbon domain HypA PF01155.19 KIY70166.1 - 0.029 14.4 2.4 0.095 12.7 0.3 2.4 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 KIY70166.1 - 0.1 12.7 7.8 2.7 8.1 0.4 2.7 2 1 0 2 2 2 0 Double zinc ribbon OrfB_Zn_ribbon PF07282.11 KIY70166.1 - 0.3 11.0 5.2 0.19 11.7 2.6 1.9 2 0 0 2 2 2 0 Putative transposase DNA-binding domain zf-RING_4 PF14570.6 KIY70166.1 - 0.88 9.4 5.3 0.83 9.5 1.7 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zinc_ribbon_10 PF10058.9 KIY70166.1 - 2.3 8.0 13.9 1.5 8.6 3.1 2.7 3 0 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein Zn-ribbon_8 PF09723.10 KIY70166.1 - 4.2 7.6 10.1 7.5 6.8 2.1 2.9 3 0 0 3 3 3 0 Zinc ribbon domain Zn_ribbon_SprT PF17283.2 KIY70166.1 - 8 6.5 10.3 10 6.1 3.1 3.5 3 0 0 3 3 3 0 SprT-like zinc ribbon domain zinc-ribbons_6 PF07191.12 KIY70166.1 - 9.9 6.2 10.5 5.4 7.1 0.9 2.9 2 1 0 2 2 2 0 zinc-ribbons HMG_box PF00505.19 KIY70167.1 - 0.00055 20.3 4.9 0.0046 17.3 1.9 2.4 2 0 0 2 2 2 2 HMG (high mobility group) box CaMBD PF02888.16 KIY70169.1 - 0.0077 16.4 0.1 0.021 15.0 0.0 1.9 2 0 0 2 2 2 1 Calmodulin binding domain HMG_box PF00505.19 KIY70171.1 - 0.00026 21.3 2.8 0.0091 16.4 0.2 2.3 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box PF00505.19 KIY70174.1 - 3.3e-11 43.4 0.6 7.2e-11 42.3 0.6 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KIY70174.1 - 0.0014 19.1 0.3 0.0029 18.2 0.3 1.6 1 0 0 1 1 1 1 HMG-box domain GFA PF04828.14 KIY70175.1 - 9.9e-14 51.5 0.1 1.4e-13 51.0 0.1 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Fungal_trans PF04082.18 KIY70176.1 - 3.9e-06 26.1 0.1 6.4e-06 25.4 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY70176.1 - 0.00025 21.1 10.7 0.00047 20.2 10.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GFA PF04828.14 KIY70177.1 - 1.2e-13 51.2 0.2 1.6e-13 50.8 0.2 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Fasciclin PF02469.22 KIY70178.1 - 3.2e-71 237.5 0.0 4e-18 65.9 0.0 5.6 5 1 0 5 5 5 5 Fasciclin domain Mito_carr PF00153.27 KIY70178.1 - 1.1e-58 195.1 5.3 1.4e-19 69.7 0.2 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein UQ_con PF00179.26 KIY70179.1 - 6.4e-20 71.2 0.0 1.1e-19 70.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Glyco_hydro_43 PF04616.14 KIY70180.1 - 1.2e-33 116.7 1.3 1.6e-33 116.2 1.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KIY70180.1 - 2e-23 83.2 0.0 3.2e-23 82.5 0.0 1.4 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain ThrE PF06738.12 KIY70181.1 - 1.1e-47 162.5 5.2 1.1e-47 162.5 5.2 2.2 2 0 0 2 2 2 1 Putative threonine/serine exporter ThrE_2 PF12821.7 KIY70181.1 - 4.1e-07 30.2 10.7 4.1e-07 30.2 10.7 2.5 2 1 0 2 2 2 1 Threonine/Serine exporter, ThrE Sacchrp_dh_C PF16653.5 KIY70182.1 - 9.3e-63 212.8 0.0 1.4e-62 212.2 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 KIY70182.1 - 6.4e-26 91.2 0.0 1e-25 90.5 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 KIY70182.1 - 1.5e-06 28.3 0.0 2.5e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 KIY70182.1 - 0.00028 20.8 0.0 0.00048 20.1 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding TrkA_N PF02254.18 KIY70182.1 - 0.096 13.0 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Semialdhyde_dh PF01118.24 KIY70182.1 - 0.13 12.7 0.0 0.22 12.0 0.0 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain GMC_oxred_N PF00732.19 KIY70183.1 - 2.1e-55 188.2 0.1 4.5e-55 187.1 0.0 1.6 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIY70183.1 - 1.5e-30 106.6 0.0 2.6e-30 105.8 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KIY70183.1 - 2.6e-05 24.4 0.0 8e-05 22.8 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KIY70183.1 - 0.0002 20.7 0.0 0.018 14.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KIY70183.1 - 0.0015 17.7 0.1 0.012 14.8 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 KIY70183.1 - 0.0018 17.6 0.0 0.018 14.3 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KIY70183.1 - 0.0019 17.3 0.1 0.0033 16.5 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 KIY70183.1 - 0.0025 17.5 1.3 0.013 15.1 0.3 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KIY70183.1 - 0.0089 14.8 0.3 0.05 12.3 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 KIY70183.1 - 0.056 12.7 0.1 0.11 11.7 0.1 1.4 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.6 KIY70183.1 - 0.11 12.5 0.2 0.29 11.1 0.1 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding Serglycin PF04360.12 KIY70183.1 - 0.35 10.8 1.8 0.72 9.8 1.8 1.4 1 0 0 1 1 1 0 Serglycin MFS_1 PF07690.16 KIY70184.1 - 2.1e-12 46.7 46.8 1.4e-08 34.1 30.6 2.7 2 1 2 4 4 4 2 Major Facilitator Superfamily SNF2_N PF00176.23 KIY70185.1 - 2.2e-71 240.4 0.0 3.1e-71 239.9 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KIY70185.1 - 1.5e-14 54.2 0.0 3.7e-14 53.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.6 KIY70185.1 - 0.00042 20.2 1.3 0.00042 20.2 1.3 1.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KIY70185.1 - 0.0037 17.1 2.3 0.01 15.7 2.3 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KIY70185.1 - 0.086 12.7 0.6 0.28 11.1 0.6 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 KIY70185.1 - 0.091 12.8 0.0 4.5 7.2 0.1 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit zinc-ribbon_6 PF10005.9 KIY70185.1 - 4.2 8.1 5.5 20 6.0 5.5 2.2 1 1 0 1 1 1 0 zinc-ribbon domain Ribonucleas_3_3 PF14622.6 KIY70187.1 - 2.6e-07 30.8 0.0 4e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.26 KIY70187.1 - 2.8e-05 24.7 0.3 6.8e-05 23.5 0.3 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif Vps62 PF06101.11 KIY70188.1 - 1.7e-07 30.0 2.8 5.2e-07 28.3 0.6 2.1 2 0 0 2 2 2 2 Vacuolar protein sorting-associated protein 62 Sec3_C PF09763.9 KIY70189.1 - 2.9e-151 505.3 0.8 3.8e-151 504.9 0.8 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.6 KIY70189.1 - 3.1e-20 72.1 0.2 6.3e-20 71.1 0.2 1.6 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH F-box PF00646.33 KIY70191.1 - 1.7e-06 27.7 1.5 2e-06 27.5 0.3 1.8 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KIY70191.1 - 2.4e-06 27.3 1.8 3.4e-06 26.8 0.5 1.9 2 0 0 2 2 2 1 F-box-like RVT_1 PF00078.27 KIY70192.1 - 1.7e-09 37.5 0.0 2.8e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 KIY70193.1 - 5.3e-08 32.6 0.0 6.7e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4577 PF15145.6 KIY70194.1 - 0.0049 16.9 1.0 0.096 12.7 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4577) SlyX PF04102.12 KIY70194.1 - 0.058 14.0 2.5 0.11 13.1 0.2 2.6 3 0 0 3 3 3 0 SlyX DUF89 PF01937.19 KIY70194.1 - 0.075 12.0 0.1 0.12 11.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF89 DUF1640 PF07798.11 KIY70194.1 - 0.13 12.3 1.6 0.38 10.8 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) Tup_N PF08581.10 KIY70194.1 - 0.26 11.6 0.6 0.79 10.1 0.2 1.9 2 0 0 2 2 2 0 Tup N-terminal Tup_N PF08581.10 KIY70195.1 - 0.00018 21.8 0.4 0.00027 21.2 0.4 1.2 1 0 0 1 1 1 1 Tup N-terminal CENP-F_leu_zip PF10473.9 KIY70195.1 - 0.00029 20.9 0.9 0.00037 20.5 0.9 1.2 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HOOK PF05622.12 KIY70195.1 - 0.0023 16.2 0.7 0.0025 16.0 0.7 1.0 1 0 0 1 1 1 1 HOOK protein APG6_N PF17675.1 KIY70195.1 - 0.0058 17.2 3.2 0.0077 16.8 3.2 1.2 1 0 0 1 1 1 1 Apg6 coiled-coil region DUF4140 PF13600.6 KIY70195.1 - 0.0079 16.6 5.7 0.65 10.5 4.1 2.4 2 1 0 2 2 2 1 N-terminal domain of unknown function (DUF4140) HAUS5 PF14817.6 KIY70195.1 - 0.008 15.0 1.6 0.0087 14.9 1.6 1.0 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 5 GAS PF13851.6 KIY70195.1 - 0.013 14.8 1.4 0.017 14.5 1.4 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding GrpE PF01025.19 KIY70195.1 - 0.035 13.8 0.9 0.046 13.4 0.9 1.2 1 0 0 1 1 1 0 GrpE Spc7 PF08317.11 KIY70195.1 - 0.069 12.0 0.6 0.075 11.9 0.6 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Atg14 PF10186.9 KIY70195.1 - 0.078 12.1 0.6 0.096 11.8 0.6 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 AAA_13 PF13166.6 KIY70195.1 - 0.091 11.4 0.9 0.11 11.2 0.9 1.0 1 0 0 1 1 1 0 AAA domain DUF1664 PF07889.12 KIY70195.1 - 0.16 12.0 0.3 0.23 11.5 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Spc24 PF08286.11 KIY70195.1 - 0.58 10.4 2.3 1.9 8.8 2.3 1.8 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 NAT PF04768.13 KIY70196.1 - 2.5e-35 121.6 0.3 2.2e-20 73.0 0.0 2.2 2 0 0 2 2 2 2 NAT, N-acetyltransferase, of N-acetylglutamate synthase F-box-like PF12937.7 KIY70197.1 - 5.5e-10 39.0 1.9 1.3e-09 37.8 0.3 2.6 2 1 0 2 2 2 1 F-box-like F-box-like PF12937.7 KIY70198.1 - 2.6e-08 33.6 0.1 1.3e-07 31.4 0.1 2.2 1 1 0 1 1 1 1 F-box-like DUF2353 PF09789.9 KIY70198.1 - 0.0021 17.5 0.7 0.0033 16.8 0.7 1.2 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) PAP_assoc PF03828.19 KIY70198.1 - 0.018 15.2 0.0 0.046 13.9 0.0 1.6 1 0 0 1 1 1 0 Cid1 family poly A polymerase TPR_MLP1_2 PF07926.12 KIY70198.1 - 0.021 14.9 4.6 0.04 14.0 4.6 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 KIY70198.1 - 0.032 13.1 2.9 0.051 12.5 2.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein OmpH PF03938.14 KIY70198.1 - 0.13 12.6 2.1 0.23 11.8 2.1 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) FliJ PF02050.16 KIY70198.1 - 0.14 12.4 5.9 0.31 11.3 5.9 1.5 1 0 0 1 1 1 0 Flagellar FliJ protein GrpE PF01025.19 KIY70198.1 - 0.22 11.2 3.4 0.38 10.4 3.4 1.3 1 0 0 1 1 1 0 GrpE UPF0242 PF06785.11 KIY70198.1 - 0.29 11.2 2.9 0.51 10.4 2.9 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TMF_DNA_bd PF12329.8 KIY70198.1 - 0.36 10.9 2.4 0.81 9.7 2.4 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Laminin_I PF06008.14 KIY70198.1 - 0.41 10.3 5.7 0.66 9.6 5.7 1.2 1 0 0 1 1 1 0 Laminin Domain I APG6_N PF17675.1 KIY70198.1 - 0.96 10.0 9.1 2 8.9 9.1 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region ABC_tran_CTD PF16326.5 KIY70198.1 - 1.9 8.8 6.2 1.6 9.0 4.0 1.9 2 0 0 2 2 2 0 ABC transporter C-terminal domain DivIC PF04977.15 KIY70198.1 - 2.8 7.8 5.1 2.1 8.2 3.1 1.8 1 1 0 1 1 1 0 Septum formation initiator ADIP PF11559.8 KIY70198.1 - 2.9 8.0 7.3 1.8 8.6 5.1 1.7 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding F-box-like PF12937.7 KIY70199.1 - 4e-08 33.0 1.5 1.2e-07 31.5 1.5 1.9 1 1 0 1 1 1 1 F-box-like MFS_1 PF07690.16 KIY70200.1 - 1.2e-43 149.4 31.2 1.2e-43 149.4 31.2 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIY70200.1 - 9.9e-15 54.3 8.0 9.9e-15 54.3 8.0 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter DUF2198 PF09964.9 KIY70200.1 - 0.16 12.1 3.7 0.3 11.2 0.7 2.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2198) DAPG_hydrolase PF18089.1 KIY70201.1 - 0.094 12.3 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 DAPG hydrolase PhiG domain ApbA_C PF08546.11 KIY70202.1 - 8.4e-09 35.7 0.0 9.2e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal PhoLip_ATPase_C PF16212.5 KIY70204.1 - 3.5e-70 236.6 31.9 3.5e-70 236.6 31.9 1.9 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KIY70204.1 - 6.5e-23 80.2 0.4 1.7e-22 78.9 0.4 1.7 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 KIY70204.1 - 4.2e-15 55.6 0.0 1e-14 54.3 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KIY70204.1 - 8.7e-14 52.3 1.7 6.3e-09 36.4 0.9 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KIY70204.1 - 2.3e-05 24.0 0.1 2.3e-05 24.0 0.1 4.1 5 1 0 5 5 5 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KIY70204.1 - 0.0023 17.7 0.1 0.057 13.2 0.1 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Herpes_LMP1 PF05297.11 KIY70204.1 - 0.12 11.6 0.0 0.28 10.3 0.0 1.5 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Ribosomal_L37e PF01907.19 KIY70205.1 - 1.8e-26 92.1 12.0 3.3e-26 91.2 12.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.7 KIY70205.1 - 0.0063 16.5 1.5 0.0096 15.9 1.5 1.3 1 0 0 1 1 1 1 Double zinc ribbon SelR PF01641.18 KIY70205.1 - 0.011 15.8 0.9 0.013 15.6 0.9 1.3 1 1 0 1 1 1 0 SelR domain HypA PF01155.19 KIY70205.1 - 0.019 15.0 0.4 0.026 14.6 0.4 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA LIM PF00412.22 KIY70205.1 - 0.028 14.7 2.2 0.04 14.2 2.2 1.3 1 0 0 1 1 1 0 LIM domain Ribosomal_S14 PF00253.21 KIY70205.1 - 0.34 10.7 7.3 0.42 10.4 0.3 2.8 1 1 1 2 2 2 0 Ribosomal protein S14p/S29e zinc_ribbon_2 PF13240.6 KIY70205.1 - 0.58 10.0 4.5 10 6.0 0.8 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-C3HC4_2 PF13923.6 KIY70205.1 - 1.3 8.9 5.8 8.9 6.3 6.6 1.8 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Sugar_tr PF00083.24 KIY70206.1 - 1.1e-112 377.2 25.3 1.3e-112 377.0 25.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY70206.1 - 4.8e-23 81.6 32.8 3.8e-20 72.1 23.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Cation_ATPase_C PF00689.21 KIY70206.1 - 9 6.0 14.1 0.83 9.3 6.2 2.6 2 1 0 2 2 2 0 Cation transporting ATPase, C-terminus O-FucT PF10250.9 KIY70208.1 - 2.6e-13 50.4 0.0 3.7e-13 49.9 0.0 1.1 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Kinesin PF00225.23 KIY70210.1 - 1.3e-96 323.5 0.0 1.8e-96 323.0 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KIY70210.1 - 1.7e-53 180.6 0.0 3.1e-53 179.7 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding TPR_MLP1_2 PF07926.12 KIY70210.1 - 0.00018 21.6 20.1 0.0016 18.5 7.0 2.5 1 1 1 2 2 2 2 TPR/MLP1/MLP2-like protein ATG16 PF08614.11 KIY70210.1 - 0.00045 20.5 21.2 0.004 17.4 21.1 2.2 1 1 0 1 1 1 1 Autophagy protein 16 (ATG16) CCDC144C PF14915.6 KIY70210.1 - 0.0016 17.6 9.6 0.0026 16.9 9.6 1.3 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region Spc7 PF08317.11 KIY70210.1 - 0.0017 17.3 15.9 0.076 11.9 4.4 2.2 1 1 1 2 2 2 2 Spc7 kinetochore protein Fez1 PF06818.15 KIY70210.1 - 0.0027 18.2 18.4 0.018 15.5 2.5 2.4 1 1 1 2 2 2 1 Fez1 KASH_CCD PF14662.6 KIY70210.1 - 0.004 17.0 13.1 0.0072 16.2 13.1 1.4 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH FPP PF05911.11 KIY70210.1 - 0.0043 15.3 10.9 0.013 13.8 10.9 1.5 1 1 0 1 1 1 1 Filament-like plant protein, long coiled-coil HMMR_N PF15905.5 KIY70210.1 - 0.025 14.1 9.4 0.048 13.1 9.4 1.4 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Uso1_p115_C PF04871.13 KIY70210.1 - 0.027 14.8 15.6 0.064 13.6 15.6 1.6 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF4407 PF14362.6 KIY70210.1 - 0.029 13.7 5.1 0.045 13.1 5.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SKA1 PF07160.12 KIY70210.1 - 0.054 13.3 5.7 0.42 10.4 1.0 2.5 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 Spc29 PF17082.5 KIY70210.1 - 0.078 12.8 5.5 0.21 11.4 4.2 2.1 1 1 1 2 2 2 0 Spindle Pole Component 29 DUF3584 PF12128.8 KIY70210.1 - 0.082 10.4 10.9 0.12 9.8 10.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) UPF0242 PF06785.11 KIY70210.1 - 0.13 12.3 13.5 0.1 12.7 9.9 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Leu_zip PF15294.6 KIY70210.1 - 0.14 11.7 9.3 0.14 11.7 6.7 1.7 1 1 0 1 1 1 0 Leucine zipper Golgin_A5 PF09787.9 KIY70210.1 - 0.21 11.0 12.5 0.37 10.2 12.5 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 zf-C4H2 PF10146.9 KIY70210.1 - 0.23 11.8 7.1 0.65 10.3 7.1 1.8 1 0 0 1 1 1 0 Zinc finger-containing protein IFT57 PF10498.9 KIY70210.1 - 0.23 10.4 8.8 0.84 8.5 8.8 1.7 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 HIP1_clath_bdg PF16515.5 KIY70210.1 - 0.41 11.3 16.4 4 8.1 1.5 3.2 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Filament PF00038.21 KIY70210.1 - 0.45 10.0 17.6 1.7 8.2 10.4 2.1 1 1 1 2 2 2 0 Intermediate filament protein DUF745 PF05335.13 KIY70210.1 - 0.46 10.2 13.8 0.12 12.1 4.1 2.7 2 1 0 3 3 2 0 Protein of unknown function (DUF745) Macoilin PF09726.9 KIY70210.1 - 0.47 8.9 9.2 0.86 8.1 9.2 1.3 1 0 0 1 1 1 0 Macoilin family MscS_porin PF12795.7 KIY70210.1 - 0.76 9.3 12.2 10 5.6 12.1 2.3 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain Med9 PF07544.13 KIY70210.1 - 0.85 9.7 9.9 8.4 6.6 3.7 2.8 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Atg14 PF10186.9 KIY70210.1 - 0.89 8.6 12.5 3.2 6.8 12.5 1.9 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DivIC PF04977.15 KIY70210.1 - 0.9 9.4 23.2 0.2 11.5 3.5 4.1 2 1 2 4 4 4 0 Septum formation initiator CENP-F_leu_zip PF10473.9 KIY70210.1 - 1 9.4 18.2 11 6.0 13.5 2.5 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Lebercilin PF15619.6 KIY70210.1 - 1.1 8.8 17.7 2.6 7.6 0.7 2.5 1 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Sec8_exocyst PF04048.14 KIY70210.1 - 1.5 8.7 4.0 7.4 6.5 0.3 3.3 2 1 2 4 4 3 0 Sec8 exocyst complex component specific domain HemX PF04375.14 KIY70210.1 - 1.5 8.0 10.4 1.6 8.0 3.5 2.2 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase Tup_N PF08581.10 KIY70210.1 - 1.8 8.9 8.7 3.6 7.9 0.8 3.2 1 1 2 3 3 3 0 Tup N-terminal OmpH PF03938.14 KIY70210.1 - 1.9 8.8 12.0 6.4 7.1 6.7 2.4 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) DivIVA PF05103.13 KIY70210.1 - 2 8.5 11.0 0.62 10.2 5.3 2.7 2 0 0 2 2 2 0 DivIVA protein FlaC_arch PF05377.11 KIY70210.1 - 2.3 8.7 11.1 11 6.5 1.6 4.0 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) COG2 PF06148.11 KIY70210.1 - 2.9 8.0 10.0 3.8 7.6 2.1 2.9 1 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 AAA_13 PF13166.6 KIY70210.1 - 3 6.4 10.1 9 4.8 10.2 1.7 1 1 0 1 1 1 0 AAA domain Occludin_ELL PF07303.13 KIY70210.1 - 3.3 8.5 6.2 34 5.2 1.3 2.6 1 1 1 2 2 2 0 Occludin homology domain DUF1664 PF07889.12 KIY70210.1 - 3.6 7.6 6.5 14 5.8 1.5 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) CENP-H PF05837.12 KIY70210.1 - 3.7 8.0 16.1 3.8 8.0 6.3 3.1 3 0 0 3 3 3 0 Centromere protein H (CENP-H) Laminin_II PF06009.12 KIY70210.1 - 4.1 7.4 8.6 10 6.2 0.5 2.8 1 1 1 2 2 2 0 Laminin Domain II FUSC PF04632.12 KIY70210.1 - 5.3 5.5 5.9 7.9 4.9 5.9 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF641 PF04859.12 KIY70210.1 - 6.7 7.1 11.1 3e+02 1.7 11.1 2.8 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) Fib_alpha PF08702.10 KIY70210.1 - 7.5 6.7 6.0 27 4.9 2.1 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family UQ_con PF00179.26 KIY70213.1 - 1.8e-18 66.5 0.0 2.6e-18 66.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Pro_isomerase PF00160.21 KIY70215.1 - 1e-39 136.3 0.2 2.3e-39 135.2 0.0 1.7 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF2852 PF11014.8 KIY70216.1 - 0.033 14.3 0.2 0.14 12.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) adh_short_C2 PF13561.6 KIY70217.1 - 2.8e-39 135.0 0.0 4.6e-38 131.1 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIY70217.1 - 2.4e-36 125.0 0.0 3.8e-36 124.4 0.0 1.3 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIY70217.1 - 4.8e-09 36.4 0.0 8.9e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KIY70217.1 - 0.057 12.5 0.0 0.078 12.1 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KIY70217.1 - 0.083 12.3 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase DUF1776 PF08643.10 KIY70217.1 - 0.099 12.0 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Peptidase_S41 PF03572.18 KIY70218.1 - 2.3e-05 24.0 0.0 4.1e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family S41 Fungal_trans PF04082.18 KIY70219.1 - 7.8e-08 31.7 0.0 1.4e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY70219.1 - 0.00042 20.4 11.6 0.00072 19.6 11.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.32 KIY70220.1 - 2.8e-08 34.3 13.4 0.0011 19.8 0.3 4.5 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY70220.1 - 0.00027 21.1 0.0 0.92 9.8 0.0 3.5 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Lactonase PF10282.9 KIY70220.1 - 0.032 13.5 0.0 0.062 12.6 0.0 1.4 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller BUD22 PF09073.10 KIY70220.1 - 0.63 9.3 21.3 0.98 8.7 21.3 1.2 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 KIY70220.1 - 8.6 4.5 12.2 16 3.6 12.2 1.4 1 0 0 1 1 1 0 CDC45-like protein F1F0-ATPsyn_F PF10791.9 KIY70222.1 - 8.3e-27 93.5 0.0 1e-26 93.2 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.9 KIY70222.1 - 0.1 13.0 0.0 0.14 12.6 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial F1F0-ATP synthase, subunit f 2HCT PF03390.15 KIY70222.1 - 0.11 11.1 0.1 0.14 10.7 0.1 1.1 1 0 0 1 1 1 0 2-hydroxycarboxylate transporter family zf-CCCH PF00642.24 KIY70223.1 - 0.00037 20.3 6.9 0.0032 17.3 0.5 2.7 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KIY70223.1 - 0.29 11.3 0.6 0.29 11.3 0.6 3.1 4 0 0 4 4 4 0 Zinc finger domain zf-CCCH_4 PF18044.1 KIY70223.1 - 3.3 7.6 0.1 3.3 7.6 0.1 3.1 3 1 0 3 3 3 0 CCCH-type zinc finger RRS1 PF04939.12 KIY70224.1 - 0.18 11.7 0.1 0.4 10.5 0.1 1.5 1 0 0 1 1 1 0 Ribosome biogenesis regulatory protein (RRS1) MCU PF04678.13 KIY70227.1 - 1.5e-30 106.6 0.0 2.4e-30 105.9 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial calcium uniporter Aminotran_1_2 PF00155.21 KIY70228.1 - 1.3e-34 120.0 0.0 1.8e-34 119.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Ribosomal_S13_N PF08069.12 KIY70228.1 - 0.033 14.2 0.0 0.1 12.7 0.0 1.8 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain Copper-fist PF00649.18 KIY70231.1 - 1e-21 76.1 2.1 1e-21 76.1 2.1 2.3 1 1 1 2 2 2 1 Copper fist DNA binding domain zinc-ribbons_6 PF07191.12 KIY70231.1 - 0.0032 17.4 3.4 0.0044 17.0 3.4 1.2 1 0 0 1 1 1 1 zinc-ribbons MFS_1 PF07690.16 KIY70232.1 - 1.3e-23 83.6 36.7 1.3e-19 70.3 15.5 2.4 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIY70232.1 - 0.00027 19.9 12.5 0.00027 19.9 12.5 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 KIY70232.1 - 0.00087 18.2 19.4 0.059 12.2 11.8 2.8 2 1 0 2 2 2 2 MFS_1 like family MaoC_dehydratas PF01575.19 KIY70234.1 - 2.1e-25 88.7 0.0 3.7e-25 87.9 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain DUF4646 PF15496.6 KIY70235.1 - 0.0006 20.4 0.0 0.0049 17.5 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4646) CDC27 PF09507.10 KIY70236.1 - 1.3 8.3 33.0 1.8 7.9 33.0 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Borrelia_P83 PF05262.11 KIY70236.1 - 9.8 4.5 31.1 12 4.3 31.1 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein EthD PF07110.11 KIY70237.1 - 5.7e-07 30.6 0.2 0.00034 21.7 0.0 2.4 2 0 0 2 2 2 2 EthD domain DUF4286 PF14114.6 KIY70237.1 - 0.00095 19.6 0.0 0.038 14.5 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4286) ABM PF03992.16 KIY70237.1 - 0.056 13.6 0.2 7.2 6.8 0.0 2.5 2 0 0 2 2 2 0 Antibiotic biosynthesis monooxygenase Aspzincin_M35 PF14521.6 KIY70238.1 - 4.7e-42 144.0 6.7 1e-41 142.9 6.7 1.6 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase HRXXH PF13933.6 KIY70238.1 - 0.0029 17.2 4.0 0.45 10.0 0.4 2.2 1 1 1 2 2 2 2 Putative peptidase family Pkinase PF00069.25 KIY70239.1 - 1.9e-15 57.0 0.0 7.2e-15 55.1 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain WD40 PF00400.32 KIY70239.1 - 4.8e-14 52.5 14.3 4e-07 30.6 0.3 6.1 5 0 0 5 5 5 4 WD domain, G-beta repeat HEAT PF02985.22 KIY70239.1 - 1.4e-10 40.5 7.1 0.013 15.7 0.1 5.8 6 0 0 6 6 6 3 HEAT repeat Pkinase_Tyr PF07714.17 KIY70239.1 - 2.1e-07 30.5 0.0 5e-06 26.0 0.0 2.8 2 1 0 2 2 2 1 Protein tyrosine kinase HEAT_2 PF13646.6 KIY70239.1 - 0.00011 22.5 0.1 18 5.8 0.0 4.4 3 1 1 4 4 4 2 HEAT repeats Cnd1 PF12717.7 KIY70239.1 - 0.0096 16.0 4.8 2.6 8.1 0.3 3.5 2 2 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Cohesin_HEAT PF12765.7 KIY70239.1 - 0.81 10.1 3.6 12 6.3 0.0 3.2 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion AAA_5 PF07728.14 KIY70240.1 - 4.7e-65 217.8 0.0 2.6e-27 95.5 0.0 3.7 3 0 0 3 3 3 3 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KIY70240.1 - 0.0037 17.7 0.1 2 8.8 0.0 3.7 3 1 1 4 4 4 2 AAA ATPase domain HSP20 PF00011.21 KIY70241.1 - 0.0001 22.4 0.0 0.0094 16.1 0.0 2.3 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KIY70241.1 - 0.00074 19.0 0.1 0.0037 16.8 0.1 2.1 1 1 0 1 1 1 1 HSP20-like domain found in ArsA NAD_binding_6 PF08030.12 KIY70242.1 - 3.3e-37 128.0 0.0 5.4e-37 127.3 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KIY70242.1 - 7.9e-23 80.6 0.0 2e-22 79.3 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 KIY70242.1 - 6.8e-15 55.3 9.3 6.8e-15 55.3 9.3 2.4 1 1 1 2 2 2 1 Ferric reductase like transmembrane component zf-MYND PF01753.18 KIY70243.1 - 1.3e-12 47.6 36.3 2e-11 43.8 14.5 3.4 3 0 0 3 3 3 2 MYND finger zf-Mss51 PF13824.6 KIY70243.1 - 8.1 6.6 17.6 2.9 8.0 5.8 2.8 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Amidohydro_1 PF01979.20 KIY70246.1 - 4.1e-19 69.1 2.0 6.7e-16 58.5 0.2 2.8 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 KIY70246.1 - 7.2e-10 38.9 2.0 5.7e-06 26.1 0.1 2.2 2 0 0 2 2 2 2 Amidohydrolase family ORC_WH_C PF18137.1 KIY70248.1 - 1.4e-41 141.9 0.0 2.4e-41 141.1 0.0 1.4 1 0 0 1 1 1 1 Origin recognition complex winged helix C-terminal ORC3_N PF07034.11 KIY70248.1 - 1.6e-29 103.1 0.7 2.2e-28 99.3 0.2 2.5 2 1 0 2 2 2 1 Origin recognition complex (ORC) subunit 3 N-terminus MCM PF00493.23 KIY70249.1 - 1.3e-96 322.1 0.0 1.8e-96 321.5 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KIY70249.1 - 1.9e-37 127.9 0.3 3.2e-37 127.2 0.3 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KIY70249.1 - 3.2e-27 94.8 0.7 7.5e-27 93.6 0.2 1.9 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 KIY70249.1 - 1.5e-17 64.0 1.1 3.3e-17 63.0 0.0 2.2 3 0 0 3 3 3 1 MCM N-terminal domain AAA_5 PF07728.14 KIY70249.1 - 5.2e-08 33.0 0.0 1.5e-07 31.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KIY70249.1 - 3.9e-07 29.7 0.0 0.00011 21.6 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KIY70249.1 - 5.3e-05 23.1 0.0 0.00099 19.0 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KIY70249.1 - 0.0044 17.4 0.0 0.02 15.2 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain Sigma54_activat PF00158.26 KIY70249.1 - 0.0072 16.0 0.0 2.2 8.0 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain DUF3256 PF11644.8 KIY70249.1 - 0.041 13.4 0.0 0.071 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3256) AAA PF00004.29 KIY70249.1 - 0.077 13.4 0.0 0.2 12.1 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zn_clus PF00172.18 KIY70250.1 - 1e-07 31.9 5.9 2.3e-07 30.8 5.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KIY70250.1 - 0.0001 21.5 0.4 0.0002 20.5 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Noelin-1 PF12308.8 KIY70250.1 - 0.076 13.0 0.1 0.15 12.1 0.1 1.4 1 0 0 1 1 1 0 Neurogenesis glycoprotein DUF2802 PF10975.8 KIY70250.1 - 0.15 12.2 2.1 4.4 7.5 1.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2802) Sporozoite_P67 PF05642.11 KIY70250.1 - 0.25 9.4 0.3 0.34 8.9 0.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen VIT1 PF01988.19 KIY70251.1 - 8.6e-65 218.6 3.0 1e-64 218.4 3.0 1.1 1 0 0 1 1 1 1 VIT family Adeno_E3 PF06040.11 KIY70251.1 - 0.037 14.2 0.0 0.072 13.3 0.0 1.5 1 0 0 1 1 1 0 Adenovirus E3 protein SLATT_fungal PF18142.1 KIY70251.1 - 1.2 9.1 6.1 0.91 9.5 0.0 2.3 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain SYF2 PF08231.12 KIY70252.1 - 1e-59 201.5 12.1 1e-59 201.5 12.1 2.0 1 1 1 2 2 2 1 SYF2 splicing factor Ead_Ea22 PF13935.6 KIY70252.1 - 3.4 8.3 14.8 0.67 10.6 4.3 2.7 1 1 1 2 2 2 0 Ead/Ea22-like protein 2OG-FeII_Oxy_2 PF13532.6 KIY70253.1 - 1.9e-19 70.7 0.0 4e-19 69.6 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RFX5_DNA_bdg PF14621.6 KIY70253.1 - 1.8 8.3 7.6 0.38 10.5 2.6 2.2 1 1 1 2 2 2 0 RFX5 DNA-binding domain zf-C2HC5 PF06221.13 KIY70253.1 - 5.3 7.1 7.1 1.7 8.7 1.6 2.4 2 0 0 2 2 2 0 Putative zinc finger motif, C2HC5-type FYVE PF01363.21 KIY70253.1 - 6.7 6.9 10.8 0.16 12.2 1.7 2.7 3 0 0 3 3 3 0 FYVE zinc finger HLH PF00010.26 KIY70254.1 - 3.3e-13 49.4 0.3 7.2e-13 48.3 0.3 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF3984 PF13136.6 KIY70254.1 - 0.91 8.9 15.5 0.2 11.1 9.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3984) PBP1_TM PF14812.6 KIY70254.1 - 1.1 9.6 11.8 4.6 7.7 0.8 3.7 3 1 1 4 4 4 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2183 PF09949.9 KIY70255.1 - 3.4e-23 81.8 0.0 5.6e-23 81.1 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) Abhydrolase_6 PF12697.7 KIY70257.1 - 3.6e-14 53.9 2.6 3.6e-14 53.9 2.6 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KIY70257.1 - 5.1e-06 26.3 0.0 9e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIY70257.1 - 2.6e-05 23.6 0.0 8.8e-05 21.9 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KIY70257.1 - 0.01 15.3 0.0 0.029 13.8 0.0 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF2920 PF11144.8 KIY70257.1 - 0.028 13.6 0.0 0.042 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Lipase_3 PF01764.25 KIY70257.1 - 0.03 14.2 0.2 0.088 12.7 0.2 1.7 2 0 0 2 2 2 0 Lipase (class 3) PGAP1 PF07819.13 KIY70257.1 - 0.21 11.3 0.0 0.33 10.6 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Pkinase PF00069.25 KIY70258.1 - 3.6e-40 138.0 0.0 5.1e-40 137.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY70258.1 - 3e-15 56.2 0.0 2.5e-14 53.2 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY70258.1 - 5.8e-07 29.1 0.0 8.2e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KIY70258.1 - 0.00064 19.7 0.1 0.026 14.5 0.0 2.3 2 1 0 2 2 2 1 Phosphotransferase enzyme family Ribosomal_S10 PF00338.22 KIY70260.1 - 1.6e-18 66.7 0.0 4.6e-18 65.2 0.0 1.8 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e WD40 PF00400.32 KIY70261.1 - 6.6e-24 83.7 9.7 1.2e-07 32.3 0.1 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY70261.1 - 1.7e-07 31.4 0.6 0.055 13.8 0.0 4.4 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIY70261.1 - 0.0077 15.2 0.0 0.081 11.9 0.0 2.2 2 0 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 KIY70261.1 - 0.0091 14.8 0.0 3.6 6.2 0.0 2.9 2 1 1 3 3 3 2 Nup133 N terminal like Cytochrom_D1 PF02239.16 KIY70261.1 - 0.023 13.3 0.0 0.051 12.1 0.0 1.6 2 0 0 2 2 2 0 Cytochrome D1 heme domain WD40_like PF17005.5 KIY70261.1 - 0.035 13.4 0.0 1.3 8.3 0.0 2.4 2 1 1 3 3 3 0 WD40-like domain Nup160 PF11715.8 KIY70261.1 - 0.13 10.9 0.3 2.3 6.7 0.0 2.9 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Ribonuclease PF00545.20 KIY70262.1 - 4.1e-08 33.9 0.0 5.1e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 ribonuclease Ribonuclease PF00545.20 KIY70263.1 - 4.4e-08 33.8 0.0 5.4e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 ribonuclease DUF3632 PF12311.8 KIY70264.1 - 9.5e-30 104.3 3.4 1.5e-29 103.7 3.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Pkinase PF00069.25 KIY70265.1 - 2e-64 217.5 0.0 2.4e-64 217.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY70265.1 - 1.9e-27 96.2 0.0 2.7e-27 95.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY70265.1 - 3.3e-06 26.6 0.0 4.7e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KIY70265.1 - 0.00013 21.4 0.0 0.00021 20.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KIY70265.1 - 0.00079 19.1 0.0 0.0014 18.3 0.0 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KIY70265.1 - 0.0018 18.2 0.2 0.58 10.0 0.2 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KIY70265.1 - 0.0066 15.4 0.0 0.012 14.6 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Borealin PF10512.9 KIY70266.1 - 8.5e-05 22.5 2.5 0.00028 20.8 0.9 2.5 3 0 0 3 3 3 1 Cell division cycle-associated protein 8 PMT PF02366.18 KIY70267.1 - 1.1e-80 270.7 18.1 2e-80 269.9 18.1 1.4 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KIY70267.1 - 3.6e-55 186.7 14.4 3.6e-55 186.7 14.4 2.3 2 0 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KIY70267.1 - 6.3e-26 91.4 0.1 9.6e-26 90.8 0.1 1.2 1 0 0 1 1 1 1 MIR domain F-box-like PF12937.7 KIY70268.1 - 0.0054 16.6 0.9 0.015 15.2 0.0 2.3 3 0 0 3 3 3 1 F-box-like LRR_4 PF12799.7 KIY70268.1 - 0.38 11.2 3.1 3.9 8.0 0.0 4.0 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) Glyco_transf_20 PF00982.21 KIY70269.1 - 1.6e-185 617.3 0.0 1.5e-184 614.2 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase family 20 Glyco_trans_1_4 PF13692.6 KIY70269.1 - 0.00031 21.2 0.0 0.00067 20.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Nbl1_Borealin_N PF10444.9 KIY70270.1 - 1.8e-05 24.3 1.5 4.5e-05 23.0 0.2 2.3 3 0 0 3 3 3 1 Nbl1 / Borealin N terminal Borealin PF10512.9 KIY70270.1 - 5.9e-05 23.0 2.1 5.9e-05 23.0 2.1 3.2 3 1 0 3 3 3 2 Cell division cycle-associated protein 8 CENP-U PF13097.6 KIY70270.1 - 0.055 13.4 2.1 0.26 11.2 0.0 2.5 2 0 0 2 2 2 0 CENP-A nucleosome associated complex (NAC) subunit APH PF01636.23 KIY70271.1 - 2.2e-13 50.7 0.0 3.8e-13 49.9 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KIY70271.1 - 0.019 14.6 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase RseA_C PF03873.13 KIY70271.1 - 0.18 12.0 0.9 0.49 10.7 0.9 1.7 1 0 0 1 1 1 0 Anti sigma-E protein RseA, C-terminal domain Hist_deacetyl PF00850.19 KIY70273.1 - 1.2e-81 274.5 0.0 1.7e-81 274.1 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Ras PF00071.22 KIY70274.1 - 4.5e-41 140.2 0.1 5.2e-41 140.0 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIY70274.1 - 1.5e-16 60.7 0.0 2.1e-16 60.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIY70274.1 - 7e-07 28.9 0.0 7.6e-07 28.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KIY70274.1 - 8.2e-05 22.7 0.0 0.00017 21.7 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase ATPase_2 PF01637.18 KIY70274.1 - 0.00023 21.2 0.1 0.00068 19.6 0.1 1.7 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_14 PF13173.6 KIY70274.1 - 0.0014 18.6 0.0 0.0039 17.2 0.0 1.7 2 0 0 2 2 2 1 AAA domain G-alpha PF00503.20 KIY70274.1 - 0.0047 16.1 0.0 0.0057 15.9 0.0 1.4 1 1 0 1 1 1 1 G-protein alpha subunit RsgA_GTPase PF03193.16 KIY70274.1 - 0.01 15.8 0.0 4.1 7.3 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase AAA_28 PF13521.6 KIY70274.1 - 0.015 15.6 0.0 0.039 14.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 KIY70274.1 - 0.027 14.2 0.1 1.8 8.3 0.0 2.3 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein SRPRB PF09439.10 KIY70274.1 - 0.038 13.4 0.0 0.055 12.9 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit TniB PF05621.11 KIY70274.1 - 0.079 12.4 0.2 0.66 9.4 0.0 2.3 3 0 0 3 3 3 0 Bacterial TniB protein Dynamin_N PF00350.23 KIY70274.1 - 0.087 12.9 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 Dynamin family AAA_16 PF13191.6 KIY70274.1 - 0.094 13.1 0.0 0.094 13.1 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain DNA_ligase_A_M PF01068.21 KIY70275.1 - 3.4e-29 101.9 0.0 6e-29 101.2 0.0 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KIY70275.1 - 1.3e-15 58.1 0.0 1.4e-13 51.5 0.0 2.3 2 0 0 2 2 2 2 DNA ligase N terminus RNA_ligase PF09414.10 KIY70275.1 - 1.8e-05 25.1 0.0 4.2e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 RNA ligase PPTA PF01239.22 KIY70276.1 - 2.4e-40 135.1 12.9 6e-09 35.3 0.0 5.6 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat DPBB_1 PF03330.18 KIY70277.1 - 0.0001 22.5 0.1 0.00018 21.7 0.1 1.5 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 KIY70277.1 - 0.026 14.4 0.2 0.044 13.6 0.1 1.4 1 1 0 1 1 1 0 Barwin family Zn_clus PF00172.18 KIY70278.1 - 7.2e-09 35.6 9.3 1.1e-08 35.0 9.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KIY70278.1 - 0.0059 15.5 1.6 0.0087 14.9 1.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY70279.1 - 6.3e-09 35.8 9.4 1e-08 35.2 9.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KIY70279.1 - 0.00031 19.7 1.7 0.00048 19.1 1.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY70280.1 - 2e-09 37.4 8.5 3.4e-09 36.7 8.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KIY70280.1 - 0.00049 19.0 0.9 0.00074 18.4 0.9 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.24 KIY70281.1 - 2e-110 369.7 17.3 2.4e-110 369.5 17.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY70281.1 - 2e-19 69.8 24.5 2e-19 69.8 24.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KIY70281.1 - 3.2e-05 22.7 0.2 3.2e-05 22.7 0.2 3.0 2 1 1 3 3 3 1 MFS/sugar transport protein TRI12 PF06609.13 KIY70281.1 - 0.00015 20.4 0.8 0.00015 20.4 0.8 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) ABC_membrane PF00664.23 KIY70282.1 - 1.5e-63 215.0 35.7 5.9e-35 121.2 12.9 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KIY70282.1 - 3.6e-51 173.3 0.0 1.2e-29 103.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KIY70282.1 - 2.7e-05 23.7 0.0 1.2 8.5 0.0 3.8 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KIY70282.1 - 4.3e-05 23.5 1.4 1.9 8.2 0.1 3.4 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KIY70282.1 - 4.3e-05 23.9 0.2 0.15 12.5 0.1 2.5 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KIY70282.1 - 0.00012 22.1 0.1 0.32 10.9 0.1 2.6 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KIY70282.1 - 0.00016 21.7 0.8 0.26 11.4 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF4574 PF15141.6 KIY70282.1 - 0.00042 20.2 0.0 0.0015 18.4 0.0 1.9 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex assembly factor 3 AAA_29 PF13555.6 KIY70282.1 - 0.0032 17.2 0.3 0.36 10.6 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain Dynamin_N PF00350.23 KIY70282.1 - 0.013 15.6 0.6 2.3 8.3 0.1 2.5 2 0 0 2 2 2 0 Dynamin family cobW PF02492.19 KIY70282.1 - 0.021 14.4 0.3 0.61 9.6 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 KIY70282.1 - 0.029 14.9 1.8 1.1 9.7 0.1 2.4 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KIY70282.1 - 0.049 13.4 0.7 21 4.8 0.0 3.3 4 0 0 4 4 4 0 IstB-like ATP binding protein Roc PF08477.13 KIY70282.1 - 0.094 12.9 0.2 33 4.7 0.0 3.2 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase MeaB PF03308.16 KIY70282.1 - 0.1 11.5 0.3 4.4 6.2 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ATP-synt_ab PF00006.25 KIY70282.1 - 0.12 12.0 0.2 2.3 7.8 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Zeta_toxin PF06414.12 KIY70282.1 - 0.23 10.7 0.1 8.5 5.6 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin MobB PF03205.14 KIY70282.1 - 0.27 11.1 0.8 2.7 7.9 0.1 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.17 KIY70282.1 - 0.62 10.1 6.5 3.5 7.6 0.1 3.0 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_22 PF13401.6 KIY70282.1 - 0.94 9.8 4.8 5.7 7.2 0.1 3.3 3 1 0 3 3 2 0 AAA domain CK_II_beta PF01214.18 KIY70283.1 - 8.1e-80 266.9 0.0 9.6e-80 266.7 0.0 1.0 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Glyco_hydro_43 PF04616.14 KIY70284.1 - 9.5e-46 156.4 3.5 1.1e-45 156.2 3.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Suf PF05843.14 KIY70285.1 - 2.4e-69 234.6 1.3 1.1e-68 232.4 0.0 2.7 4 0 0 4 4 4 1 Suppressor of forked protein (Suf) TPR_14 PF13428.6 KIY70285.1 - 2.5e-06 27.8 8.2 0.016 16.0 0.1 6.9 5 2 2 7 7 7 1 Tetratricopeptide repeat TPR_6 PF13174.6 KIY70285.1 - 9.3e-05 22.8 1.5 0.045 14.4 0.0 5.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 KIY70285.1 - 0.0067 16.9 0.8 5.3 7.6 0.1 3.8 3 1 0 3 3 3 1 Tetratricopeptide repeat DUF5082 PF16888.5 KIY70285.1 - 0.092 13.0 0.0 0.43 10.9 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) RP-C_C PF11800.8 KIY70285.1 - 4.9 7.2 5.7 10 6.1 0.7 2.9 3 0 0 3 3 3 0 Replication protein C C-terminal region tRNA-synt_1d PF00750.19 KIY70286.1 - 5.3e-107 357.8 4.4 7.2e-107 357.3 4.4 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 KIY70286.1 - 1.5e-18 67.1 0.0 2.7e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 DALR anticodon binding domain Guanylate_kin PF00625.21 KIY70287.1 - 1.5e-62 210.5 0.0 2e-62 210.1 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.6 KIY70287.1 - 4e-08 33.8 0.0 8.7e-08 32.7 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 KIY70287.1 - 7.7e-06 26.1 0.0 6.6e-05 23.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KIY70287.1 - 0.00016 22.0 0.0 0.00034 20.9 0.0 1.6 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KIY70287.1 - 0.00024 21.2 0.0 0.00051 20.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_18 PF13238.6 KIY70287.1 - 0.00038 21.0 0.0 0.0011 19.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KIY70287.1 - 0.0011 18.9 0.1 0.0056 16.6 0.1 1.9 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 KIY70287.1 - 0.0014 19.0 0.0 0.0043 17.4 0.0 1.8 2 0 0 2 2 2 1 RNA helicase RsgA_GTPase PF03193.16 KIY70287.1 - 0.0014 18.5 0.0 0.0025 17.7 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_5 PF07728.14 KIY70287.1 - 0.0036 17.3 0.1 0.029 14.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA PF00004.29 KIY70287.1 - 0.0039 17.6 0.0 0.014 15.8 0.0 1.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 KIY70287.1 - 0.0052 17.3 0.0 0.01 16.3 0.0 1.5 2 0 0 2 2 2 1 ABC transporter Rad17 PF03215.15 KIY70287.1 - 0.0099 15.8 0.0 0.023 14.6 0.0 1.6 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_29 PF13555.6 KIY70287.1 - 0.01 15.5 0.2 0.023 14.4 0.0 1.6 2 0 0 2 2 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 KIY70287.1 - 0.011 15.3 0.0 0.024 14.1 0.0 1.5 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_14 PF13173.6 KIY70287.1 - 0.021 14.9 0.0 0.059 13.4 0.0 1.9 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KIY70287.1 - 0.022 14.5 0.1 0.028 14.1 0.1 1.6 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 KIY70287.1 - 0.041 13.8 0.0 0.078 12.9 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Roc PF08477.13 KIY70287.1 - 0.084 13.1 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase WEMBL PF05701.11 KIY70287.1 - 0.086 11.5 0.0 0.11 11.1 0.0 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light AAA_17 PF13207.6 KIY70287.1 - 0.11 12.9 0.1 1 9.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KIY70287.1 - 0.18 11.2 0.0 0.27 10.6 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Pox_A32 PF04665.12 KIY70287.1 - 0.18 11.2 0.0 0.5 9.8 0.0 1.7 2 0 0 2 2 2 0 Poxvirus A32 protein Pkinase PF00069.25 KIY70288.1 - 1.1e-61 208.5 0.0 1.7e-61 207.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY70288.1 - 7.8e-33 113.8 0.0 1.1e-32 113.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY70288.1 - 3.3e-10 39.7 0.0 6e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KIY70288.1 - 1.7e-05 23.8 0.0 3e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KIY70288.1 - 3.5e-05 23.3 0.6 6.9e-05 22.3 0.1 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIY70288.1 - 0.0014 18.6 0.5 0.0028 17.6 0.5 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 KIY70288.1 - 0.059 13.0 0.1 4 7.0 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 KIY70288.1 - 0.15 11.0 0.1 0.23 10.4 0.1 1.4 1 0 0 1 1 1 0 Haspin like kinase domain SCA7 PF08313.12 KIY70290.1 - 3.1e-23 81.5 1.7 1.1e-22 79.7 1.7 1.9 1 0 0 1 1 1 1 SCA7, zinc-binding domain MAS20 PF02064.15 KIY70290.1 - 0.0082 16.2 1.6 0.0082 16.2 1.6 2.2 2 0 0 2 2 2 1 MAS20 protein import receptor tRNA-synt_2b PF00587.25 KIY70291.1 - 9.3e-38 130.0 1.0 1.2e-37 129.6 0.1 1.6 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 KIY70291.1 - 2.4e-18 66.3 8.6 2.4e-18 66.3 8.6 1.7 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain Swi3 PF07962.12 KIY70291.1 - 0.064 13.3 0.1 0.17 11.9 0.1 1.7 1 0 0 1 1 1 0 Replication Fork Protection Component Swi3 DUF3450 PF11932.8 KIY70291.1 - 0.47 9.7 6.0 0.78 9.0 6.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Maf PF02545.14 KIY70293.1 - 3.7e-44 150.5 0.0 4.3e-44 150.3 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein LSM PF01423.22 KIY70294.1 - 9.8e-19 66.8 1.4 1.3e-18 66.4 1.4 1.2 1 0 0 1 1 1 1 LSM domain BPL_C PF02237.17 KIY70294.1 - 0.019 14.9 0.2 0.035 14.0 0.2 1.4 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain SM-ATX PF14438.6 KIY70294.1 - 0.029 14.5 0.1 0.037 14.2 0.1 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain RRM_1 PF00076.22 KIY70296.1 - 1.9e-31 107.7 0.0 3.7e-16 58.7 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KIY70296.1 - 3.1e-05 24.0 0.0 8.8e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 RNA binding motif Nup35_RRM_2 PF14605.6 KIY70296.1 - 0.00026 20.9 0.0 0.0027 17.7 0.0 2.3 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif SUIM_assoc PF16619.5 KIY70296.1 - 0.0065 16.5 6.9 0.024 14.7 6.9 2.0 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 RRM_5 PF13893.6 KIY70296.1 - 0.011 15.3 0.0 0.028 14.0 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KIY70296.1 - 0.032 14.3 0.0 0.86 9.8 0.1 3.0 3 0 0 3 3 3 0 RNA recognition motif Secretin_N_2 PF07655.13 KIY70296.1 - 0.18 12.4 5.3 19 5.9 5.7 3.0 2 0 0 2 2 2 0 Secretin N-terminal domain SARAF PF06682.12 KIY70296.1 - 2.5 7.7 8.5 0.27 10.8 1.1 2.5 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis Aldo_ket_red PF00248.21 KIY70297.1 - 2.1e-68 230.7 0.0 2.6e-68 230.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Hepar_II_III PF07940.13 KIY70298.1 - 1.6e-10 41.0 1.2 2.7e-10 40.3 1.2 1.3 1 0 0 1 1 1 1 Heparinase II/III-like protein Rick_17kDa_Anti PF05433.15 KIY70298.1 - 0.021 14.7 0.3 0.049 13.5 0.3 1.6 1 0 0 1 1 1 0 Glycine zipper 2TM domain Fungal_trans PF04082.18 KIY70299.1 - 7.4e-20 71.1 0.3 1.7e-19 69.9 0.3 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY70299.1 - 0.00023 21.2 13.0 0.00052 20.1 13.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PilJ PF13675.6 KIY70299.1 - 0.088 12.8 0.4 0.27 11.3 0.1 2.0 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term JAKMIP_CC3 PF16034.5 KIY70299.1 - 0.09 12.7 0.1 0.21 11.5 0.1 1.5 1 0 0 1 1 1 0 JAKMIP CC3 domain Acyl_transf_2 PF02273.15 KIY70299.1 - 0.18 11.0 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 Acyl transferase TFIID_30kDa PF03540.13 KIY70300.1 - 5.2e-26 90.3 0.0 8e-26 89.7 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit Bromo_TP PF07524.13 KIY70300.1 - 0.0015 18.5 0.1 0.26 11.3 0.0 2.2 2 0 0 2 2 2 2 Bromodomain associated DUF3464 PF11947.8 KIY70300.1 - 0.026 14.3 0.0 0.037 13.8 0.0 1.1 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Ribosomal_60s PF00428.19 KIY70300.1 - 0.047 14.3 2.4 0.98 10.1 0.0 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein FAD_binding_3 PF01494.19 KIY70301.1 - 3.2e-17 62.8 0.0 1.2e-16 60.9 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KIY70301.1 - 1e-06 28.8 0.0 3.4e-06 27.2 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KIY70301.1 - 2.1e-05 24.3 0.2 0.0019 17.9 0.1 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 KIY70301.1 - 2.6e-05 23.7 0.1 0.0041 16.5 0.0 2.7 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 KIY70301.1 - 0.00019 20.8 0.4 0.0024 17.2 0.1 2.0 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KIY70301.1 - 0.00057 19.1 0.1 0.00093 18.4 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KIY70301.1 - 0.0006 18.6 0.0 0.016 13.9 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 KIY70301.1 - 0.024 13.9 0.0 0.16 11.2 0.0 2.1 2 0 0 2 2 2 0 Thi4 family FAD_oxidored PF12831.7 KIY70301.1 - 0.071 12.4 0.0 0.096 12.0 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase polyprenyl_synt PF00348.17 KIY70302.1 - 6.6e-63 212.1 0.0 2.6e-62 210.2 0.0 1.8 1 1 0 1 1 1 1 Polyprenyl synthetase DUF3429 PF11911.8 KIY70303.1 - 6.1e-39 133.6 14.3 8.1e-39 133.2 14.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) FAD_binding_4 PF01565.23 KIY70304.1 - 6e-15 55.2 0.1 1e-14 54.4 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KIY70304.1 - 2.4e-10 40.4 0.4 6.1e-10 39.1 0.4 1.7 1 0 0 1 1 1 1 Berberine and berberine like Synaptobrevin PF00957.21 KIY70305.1 - 4.7e-15 55.1 0.8 9.2e-15 54.2 0.8 1.4 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 KIY70305.1 - 2e-12 47.0 0.0 3.8e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain hDGE_amylase PF14701.6 KIY70306.1 - 1.6e-160 535.0 0.0 2.1e-160 534.6 0.0 1.1 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 KIY70306.1 - 1.3e-120 402.9 0.0 1.7e-120 402.5 0.0 1.1 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 KIY70306.1 - 1.4e-78 264.1 0.0 2.3e-78 263.4 0.0 1.4 1 0 0 1 1 1 1 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 KIY70306.1 - 6.8e-21 74.2 0.0 1.5e-20 73.1 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme zf-C3HC4 PF00097.25 KIY70308.1 - 1.8e-09 37.3 9.3 2e-09 37.2 6.9 2.4 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH PF00642.24 KIY70308.1 - 2.1e-07 30.7 27.4 3.3e-05 23.7 2.6 4.0 3 1 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.6 KIY70308.1 - 2.5e-07 30.5 9.9 1e-06 28.5 8.5 2.7 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIY70308.1 - 3.8e-07 30.3 7.5 3.8e-07 30.3 7.5 3.2 2 1 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 KIY70308.1 - 5.3e-07 29.5 6.8 5.3e-07 29.5 6.8 2.5 2 1 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KIY70308.1 - 7.9e-07 29.0 1.7 7.9e-07 29.0 1.7 2.5 2 1 1 3 3 3 1 RING-type zinc-finger zf_CCCH_4 PF18345.1 KIY70308.1 - 1.4e-06 28.2 7.5 1.4e-06 28.2 7.5 4.6 4 1 0 4 4 4 1 Zinc finger domain zf-C3HC4_2 PF13923.6 KIY70308.1 - 1.9e-05 24.4 2.2 1.9e-05 24.4 2.2 4.1 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KIY70308.1 - 3.7e-05 23.9 3.7 3.7e-05 23.9 3.7 2.6 3 1 1 4 4 4 1 RING-H2 zinc finger domain Torus PF16131.5 KIY70308.1 - 4.4e-05 24.1 16.7 7.1e-05 23.5 0.5 3.7 2 2 1 3 3 3 2 Torus domain zf-CCCH_4 PF18044.1 KIY70308.1 - 0.00065 19.4 4.7 0.00065 19.4 4.7 4.2 5 0 0 5 5 4 2 CCCH-type zinc finger Prok-RING_4 PF14447.6 KIY70308.1 - 0.001 18.9 6.0 0.001 18.9 6.0 2.6 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KIY70308.1 - 0.0018 18.4 7.4 0.011 15.8 7.5 2.4 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING Tmpp129 PF10272.9 KIY70308.1 - 0.0097 15.2 3.2 0.015 14.6 3.2 1.3 1 0 0 1 1 1 1 Putative transmembrane protein precursor YyzF PF14116.6 KIY70308.1 - 0.1 12.6 3.5 4.2 7.5 0.3 3.5 3 0 0 3 3 3 0 YyzF-like protein zf-RING_11 PF17123.5 KIY70308.1 - 0.27 11.0 7.7 0.47 10.3 5.7 2.4 2 1 0 2 2 2 0 RING-like zinc finger FANCL_C PF11793.8 KIY70308.1 - 0.59 10.3 9.6 0.89 9.8 7.1 2.6 2 1 0 2 2 2 0 FANCL C-terminal domain zf-CCCH_2 PF14608.6 KIY70308.1 - 0.9 10.1 28.8 2.5 8.7 3.0 3.8 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger zf-ANAPC11 PF12861.7 KIY70308.1 - 4.6 7.4 13.3 0.16 12.1 5.2 2.8 2 2 1 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-CCCH_3 PF15663.5 KIY70308.1 - 8.5 6.6 16.4 0.24 11.6 2.3 3.3 2 2 2 4 4 4 0 Zinc-finger containing family SAGA-Tad1 PF12767.7 KIY70309.1 - 8.9e-27 94.3 0.2 1.7e-26 93.4 0.2 1.4 1 1 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit TAF4 PF05236.14 KIY70309.1 - 0.022 14.5 0.2 0.036 13.8 0.2 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family DUF1707 PF08044.11 KIY70309.1 - 0.046 13.8 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1707) Glyco_hydro_61 PF03443.14 KIY70310.1 - 9.3e-38 130.2 0.3 1.5e-37 129.5 0.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 RNA_pol_Rpc4 PF05132.14 KIY70311.1 - 3.3e-28 99.0 1.3 3.3e-28 99.0 1.3 2.9 3 2 0 3 3 3 1 RNA polymerase III RPC4 Protocadherin PF08374.11 KIY70311.1 - 0.17 11.8 0.1 0.33 10.9 0.1 1.5 1 0 0 1 1 1 0 Protocadherin DUF1957 PF09210.11 KIY70312.1 - 0.25 11.8 1.2 3.1 8.2 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1957) RecQ_Zn_bind PF16124.5 KIY70313.1 - 0.051 14.3 2.3 0.35 11.6 0.6 2.3 2 0 0 2 2 2 0 RecQ zinc-binding DEAD PF00270.29 KIY70314.1 - 3.8e-17 62.6 0.0 1.7e-16 60.5 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 KIY70314.1 - 0.00078 19.5 0.0 0.0017 18.4 0.0 1.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KIY70314.1 - 0.0014 19.0 0.0 0.0095 16.3 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Pribosyltran PF00156.27 KIY70315.1 - 0.0048 16.4 0.1 0.011 15.3 0.1 1.6 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Mito_carr PF00153.27 KIY70316.1 - 1.1e-65 217.6 2.0 2.9e-22 78.4 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KIY70316.1 - 0.0087 15.2 2.3 0.71 9.0 0.2 3.1 1 1 2 3 3 3 2 Gammaproteobacterial serine protease Fer2_2 PF01799.20 KIY70317.1 - 0.019 15.0 0.0 0.036 14.1 0.0 1.4 1 0 0 1 1 1 0 [2Fe-2S] binding domain SET PF00856.28 KIY70318.1 - 5.7e-12 46.3 0.0 2e-10 41.3 0.0 2.4 1 1 0 1 1 1 1 SET domain Orthopox_A43R PF06517.11 KIY70318.1 - 0.0057 16.5 0.2 0.22 11.3 0.1 2.2 2 0 0 2 2 2 2 Orthopoxvirus A43R protein Myosin_head PF00063.21 KIY70319.1 - 5.4e-257 854.4 0.0 1.4e-256 853.0 0.0 1.8 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_N PF02736.19 KIY70319.1 - 8.8e-11 41.5 0.7 3e-10 39.8 0.7 2.0 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Myosin_tail_1 PF01576.19 KIY70319.1 - 6.7e-10 37.5 289.0 1.6e-06 26.3 106.7 5.3 1 1 2 3 3 3 3 Myosin tail AAA_22 PF13401.6 KIY70319.1 - 0.037 14.3 0.0 0.037 14.3 0.0 5.7 6 2 0 6 6 6 0 AAA domain DUF3621 PF12285.8 KIY70319.1 - 7.2 7.1 9.1 1.1 9.6 2.8 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3621) MFS_1 PF07690.16 KIY70320.1 - 2.7e-40 138.4 33.1 2.7e-40 138.4 33.1 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIY70320.1 - 2.3e-07 30.0 9.1 2.3e-07 30.0 9.1 1.9 2 1 0 2 2 2 1 Sugar (and other) transporter Caveolin PF01146.17 KIY70320.1 - 0.076 13.0 7.3 0.11 12.4 0.2 2.8 2 0 0 2 2 2 0 Caveolin Ribosomal_S19 PF00203.21 KIY70322.1 - 3.7e-31 106.9 0.2 5.4e-31 106.3 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 FliH PF02108.16 KIY70322.1 - 0.18 11.9 0.0 0.22 11.6 0.0 1.1 1 0 0 1 1 1 0 Flagellar assembly protein FliH Ribosomal_60s PF00428.19 KIY70323.1 - 5.2e-29 100.7 6.8 6.1e-29 100.4 6.8 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein PBP PF01161.20 KIY70324.1 - 1.1e-18 67.8 0.1 1.3e-18 67.6 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein CBM_20 PF00686.19 KIY70325.1 - 9.7e-31 105.5 0.2 2.1e-30 104.5 0.2 1.6 1 0 0 1 1 1 1 Starch binding domain Alpha-amylase PF00128.24 KIY70325.1 - 1.6e-16 60.8 0.0 4.7e-16 59.3 0.0 1.6 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Cerato-platanin PF07249.12 KIY70325.1 - 0.055 13.6 4.1 0.04 14.0 1.6 2.1 2 0 0 2 2 2 0 Cerato-platanin F-box-like PF12937.7 KIY70326.1 - 0.0023 17.8 1.0 0.0066 16.3 1.0 1.9 1 1 0 1 1 1 1 F-box-like DSPc PF00782.20 KIY70327.1 - 3.1e-28 98.2 0.1 3.7e-28 98.0 0.1 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 KIY70327.1 - 1.6e-05 25.1 0.1 2.5e-05 24.5 0.1 1.2 1 0 0 1 1 1 1 Rit1 DUSP-like domain Y_phosphatase PF00102.27 KIY70327.1 - 0.0036 16.9 0.0 0.0043 16.7 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KIY70327.1 - 0.028 14.5 0.0 0.039 14.1 0.0 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate Myotub-related PF06602.14 KIY70327.1 - 0.043 12.7 0.0 0.056 12.4 0.0 1.2 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain UCR_14kD PF02271.16 KIY70328.1 - 1.7e-36 124.2 1.1 2e-36 124.0 1.1 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit NDK PF00334.19 KIY70329.1 - 1.2e-53 180.7 0.0 1.4e-53 180.5 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase SNF2_N PF00176.23 KIY70330.1 - 1.8e-47 161.8 0.0 2.6e-47 161.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KIY70330.1 - 4e-23 81.9 0.0 1e-19 70.9 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 KIY70330.1 - 5.7e-05 22.4 0.0 0.00012 21.3 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 KIY70330.1 - 0.00014 21.9 0.0 0.0011 18.9 0.0 2.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_34 PF13872.6 KIY70330.1 - 0.081 11.8 0.1 5.1 5.9 0.0 2.4 2 0 0 2 2 2 0 P-loop containing NTP hydrolase pore-1 VIGSSK PF14773.6 KIY70330.1 - 0.088 12.9 0.0 0.25 11.5 0.0 1.7 1 0 0 1 1 1 0 Helicase-associated putative binding domain, C-terminal WD40 PF00400.32 KIY70331.1 - 1.8e-58 193.1 19.5 5.7e-10 39.6 0.2 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY70331.1 - 9e-18 64.4 5.0 0.0036 17.6 0.2 6.1 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIY70331.1 - 1.3e-10 41.5 0.6 0.0029 17.5 0.1 3.9 1 1 3 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KIY70331.1 - 1.1e-07 30.9 10.2 0.15 10.7 0.3 5.2 2 2 4 6 6 6 4 Nucleoporin Nup120/160 WD40_like PF17005.5 KIY70331.1 - 1.1e-05 24.9 0.8 0.072 12.4 0.0 3.4 2 2 2 4 4 4 2 WD40-like domain Ge1_WD40 PF16529.5 KIY70331.1 - 6.8e-05 22.0 9.3 0.81 8.6 0.1 4.5 2 2 1 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein CDtoxinA PF03498.14 KIY70331.1 - 0.00049 19.7 1.2 0.022 14.3 0.2 2.4 1 1 1 2 2 2 1 Cytolethal distending toxin A/C domain Pectate_lyase22 PF14583.6 KIY70331.1 - 0.0016 17.2 0.1 0.012 14.3 0.0 2.1 1 1 1 2 2 2 1 Oligogalacturonate lyase Kelch_6 PF13964.6 KIY70331.1 - 0.012 15.8 1.0 8 6.9 0.1 2.9 2 0 0 2 2 2 0 Kelch motif DUF1513 PF07433.11 KIY70331.1 - 0.03 13.4 1.0 11 5.0 0.1 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF1513) Coatomer_WDAD PF04053.14 KIY70331.1 - 0.051 12.6 1.2 0.28 10.2 0.0 2.2 2 1 1 3 3 3 0 Coatomer WD associated region Utp8 PF10395.9 KIY70331.1 - 0.22 10.0 0.0 0.46 8.9 0.0 1.4 1 1 0 1 1 1 0 Utp8 family CAP_N PF01213.19 KIY70331.1 - 5.1 6.5 7.9 7.9 5.9 7.9 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Ras PF00071.22 KIY70332.1 - 4.8e-34 117.3 0.4 5.7e-34 117.1 0.4 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIY70332.1 - 1.9e-25 89.4 0.4 3.2e-25 88.7 0.1 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIY70332.1 - 7.5e-08 32.0 0.1 9.8e-08 31.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KIY70332.1 - 3.2e-07 30.0 0.4 4.1e-07 29.6 0.4 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DLIC PF05783.11 KIY70332.1 - 0.009 14.9 0.3 1 8.1 0.0 2.1 1 1 1 2 2 2 2 Dynein light intermediate chain (DLIC) TniB PF05621.11 KIY70332.1 - 0.021 14.2 0.0 2.3 7.6 0.0 2.3 2 1 0 2 2 2 0 Bacterial TniB protein G-alpha PF00503.20 KIY70332.1 - 0.044 13.0 1.5 0.12 11.5 0.1 2.2 1 1 1 2 2 2 0 G-protein alpha subunit MMR_HSR1 PF01926.23 KIY70332.1 - 0.11 12.5 0.0 0.18 11.9 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase Transcrip_reg PF01709.20 KIY70333.1 - 1.7e-62 211.0 0.0 1.9e-62 210.8 0.0 1.0 1 0 0 1 1 1 1 Transcriptional regulator Glyco_hydro_127 PF07944.12 KIY70334.1 - 2e-21 76.1 0.0 3.6e-21 75.2 0.0 1.4 1 0 0 1 1 1 1 Beta-L-arabinofuranosidase, GH127 GUN4_N PF16416.5 KIY70335.1 - 0.0045 16.9 0.0 0.051 13.6 0.0 2.1 1 1 0 1 1 1 1 ARM-like repeat domain, GUN4-N terminal SnoaL_3 PF13474.6 KIY70335.1 - 0.019 15.3 0.1 0.026 14.8 0.1 1.2 1 0 0 1 1 1 0 SnoaL-like domain DUF4440 PF14534.6 KIY70335.1 - 0.02 15.3 0.1 0.041 14.3 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4440) SCO1-SenC PF02630.14 KIY70336.1 - 5e-48 162.4 0.1 8.2e-48 161.7 0.1 1.3 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 KIY70336.1 - 2.6e-08 33.8 0.1 4.3e-07 29.9 0.1 2.2 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 KIY70336.1 - 3.4e-06 27.3 0.2 7.4e-06 26.2 0.2 1.6 1 1 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 KIY70336.1 - 0.065 12.9 0.2 1.2 8.8 0.2 2.4 1 1 0 1 1 1 0 Redoxin ATG7_N PF16420.5 KIY70337.1 - 9.9e-84 281.5 0.0 1.2e-83 281.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 KIY70337.1 - 2.5e-46 158.0 0.0 4.1e-46 157.3 0.0 1.3 1 0 0 1 1 1 1 ThiF family 2-Hacid_dh_C PF02826.19 KIY70337.1 - 0.21 10.9 0.0 1.7 7.9 0.0 2.3 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CAP_GLY PF01302.25 KIY70338.1 - 3.9e-18 65.2 1.6 6.5e-18 64.5 1.6 1.4 1 0 0 1 1 1 1 CAP-Gly domain CLIP1_ZNF PF16641.5 KIY70338.1 - 0.0029 17.5 16.1 0.09 12.7 1.7 2.4 2 0 0 2 2 2 2 CLIP1 zinc knuckle zf-CCHC_4 PF14392.6 KIY70338.1 - 0.43 10.4 3.9 6.9 6.5 0.3 2.6 2 0 0 2 2 2 0 Zinc knuckle HTH_IclR PF09339.10 KIY70339.1 - 0.027 14.3 0.1 0.027 14.3 0.1 2.2 3 0 0 3 3 3 0 IclR helix-turn-helix domain F-box-like PF12937.7 KIY70339.1 - 0.11 12.4 3.3 0.31 11.0 3.3 1.8 1 1 0 1 1 1 0 F-box-like GDI PF00996.18 KIY70340.1 - 4.3e-45 154.0 0.0 5.4e-45 153.7 0.0 1.1 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.6 KIY70340.1 - 0.0041 17.3 0.0 0.01 16.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain PNTB PF02233.16 KIY70341.1 - 0.18 10.7 0.1 0.35 9.7 0.1 1.4 1 0 0 1 1 1 0 NAD(P) transhydrogenase beta subunit bZIP_1 PF00170.21 KIY70342.1 - 2.1e-06 27.7 8.0 3.6e-06 27.0 8.0 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KIY70342.1 - 4.3e-05 23.5 13.4 0.001 19.1 7.0 2.3 1 1 1 2 2 2 2 Basic region leucine zipper SlyX PF04102.12 KIY70342.1 - 0.026 15.1 0.5 0.026 15.1 0.5 2.0 2 0 0 2 2 2 0 SlyX bZIP_Maf PF03131.17 KIY70342.1 - 0.17 12.4 5.2 0.33 11.5 5.2 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor Scm3 PF10384.9 KIY70347.1 - 6.3e-07 29.0 0.1 1.5e-06 27.8 0.1 1.7 1 0 0 1 1 1 1 Centromere protein Scm3 Cullin PF00888.22 KIY70348.1 - 1.9e-184 614.8 13.1 3e-184 614.1 13.1 1.3 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KIY70348.1 - 1.2e-26 92.5 3.8 5.4e-26 90.4 3.6 2.3 2 0 0 2 2 2 1 Cullin protein neddylation domain UCH PF00443.29 KIY70350.1 - 1.6e-31 109.8 0.0 2.4e-31 109.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KIY70350.1 - 1.7e-05 24.6 2.3 7.4e-05 22.5 2.3 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF1351 PF07083.11 KIY70350.1 - 0.0047 16.7 0.2 0.0076 16.0 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1351) DEAD PF00270.29 KIY70351.1 - 1.7e-43 148.4 0.0 2.6e-43 147.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIY70351.1 - 2.1e-22 79.5 0.0 1.4e-20 73.7 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIY70351.1 - 2.8e-07 30.7 0.0 4.9e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KIY70351.1 - 4.8e-05 23.2 0.1 0.00015 21.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KIY70351.1 - 0.0012 19.2 0.0 0.0019 18.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain ERCC3_RAD25_C PF16203.5 KIY70351.1 - 0.0022 17.2 0.0 0.0046 16.2 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase UvrD-helicase PF00580.21 KIY70351.1 - 0.034 13.7 0.0 0.051 13.1 0.0 1.3 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain DUF1897 PF09005.10 KIY70351.1 - 0.11 12.0 0.3 0.25 10.9 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1897) DIOX_N PF14226.6 KIY70352.1 - 9e-31 107.1 0.8 1.2e-30 106.7 0.1 1.6 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KIY70352.1 - 4.5e-20 72.0 0.0 8.5e-20 71.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF2385 PF09539.10 KIY70352.1 - 0.094 13.3 0.0 0.63 10.6 0.0 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2385) Transp_cyt_pur PF02133.15 KIY70353.1 - 1.4e-77 261.3 40.0 1.8e-77 261.0 40.0 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Phage_holin_Dp1 PF16938.5 KIY70353.1 - 0.29 11.4 2.0 0.48 10.7 0.5 2.2 2 0 0 2 2 2 0 Putative phage holin Dp-1 HNH_2 PF13391.6 KIY70354.1 - 4.5e-07 29.9 0.0 1.1e-06 28.7 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease Alpha-amylase PF00128.24 KIY70355.1 - 7.3e-116 387.4 0.3 1.5e-115 386.4 0.1 1.5 2 0 0 2 2 2 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 KIY70355.1 - 1.4e-09 37.9 0.0 2.7e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain DUF3459 PF11941.8 KIY70355.1 - 0.0022 18.3 0.0 0.0071 16.6 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3459) hDGE_amylase PF14701.6 KIY70355.1 - 0.0057 15.8 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain Glyco_hydro_42C PF08533.10 KIY70355.1 - 0.064 13.0 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Beta-galactosidase C-terminal domain Thy1 PF02511.15 KIY70355.1 - 0.098 12.4 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Thymidylate synthase complementing protein Ribosomal_L1 PF00687.21 KIY70356.1 - 1.4e-47 162.1 2.4 1.6e-47 161.9 2.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family AbiEi_3 PF11459.8 KIY70357.1 - 0.073 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin, Type IV TA system CortBP2 PF09727.9 KIY70357.1 - 0.53 10.2 4.1 0.1 12.5 0.5 1.7 2 0 0 2 2 2 0 Cortactin-binding protein-2 Cep57_CLD PF14073.6 KIY70358.1 - 3e-05 24.1 6.9 3e-05 24.1 6.9 1.9 3 0 0 3 3 3 1 Centrosome localisation domain of Cep57 zf-C4H2 PF10146.9 KIY70358.1 - 0.0058 17.0 3.4 0.016 15.6 3.4 1.7 1 0 0 1 1 1 1 Zinc finger-containing protein TSC22 PF01166.18 KIY70358.1 - 0.065 13.6 3.0 5.1 7.5 0.1 3.2 3 0 0 3 3 3 0 TSC-22/dip/bun family Sp38 PF07354.12 KIY70358.1 - 0.18 11.3 0.1 0.58 9.6 0.1 1.9 2 0 0 2 2 2 0 Zona-pellucida-binding protein (Sp38) GFD1 PF17331.2 KIY70358.1 - 0.77 10.0 3.6 0.82 9.9 1.5 2.2 2 0 0 2 2 2 0 GFD1 mRNA transport factor Pkinase PF00069.25 KIY70359.1 - 4e-40 137.8 0.0 4.8e-22 78.6 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KIY70359.1 - 3e-12 46.4 0.0 2.2e-09 37.0 0.0 2.8 2 1 0 2 2 2 2 Protein tyrosine kinase FTA2 PF13095.6 KIY70359.1 - 0.025 14.2 0.0 0.063 12.9 0.0 1.7 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KIY70359.1 - 0.028 14.3 0.0 0.18 11.7 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KIY70359.1 - 0.11 11.3 0.0 0.2 10.4 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 KIY70359.1 - 0.11 11.8 0.0 4.1 6.6 0.0 2.7 3 0 0 3 3 3 0 Kinase-like Glyco_hydro_43 PF04616.14 KIY70360.1 - 6.3e-06 25.7 2.0 1e-05 25.0 2.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 zf-C3HC4_3 PF13920.6 KIY70361.1 - 8.1e-07 28.8 8.0 8.1e-07 28.8 8.0 3.7 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-H2C2_5 PF13909.6 KIY70361.1 - 0.00035 20.2 1.3 0.0056 16.4 0.0 3.4 2 0 0 2 2 2 1 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 KIY70361.1 - 0.62 10.6 0.0 0.4 11.2 2.5 5.2 6 0 0 6 6 6 0 Zinc finger, C2H2 type Band_7 PF01145.25 KIY70363.1 - 3.2e-24 85.9 3.8 4.8e-24 85.3 3.8 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Clathrin_bdg PF15045.6 KIY70364.1 - 0.068 13.2 0.1 0.16 12.0 0.1 1.5 1 0 0 1 1 1 0 Clathrin-binding box of Aftiphilin, vesicle trafficking HEPN_RiboL-PSP PF18735.1 KIY70364.1 - 0.13 12.2 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 RiboL-PSP-HEPN p450 PF00067.22 KIY70366.1 - 8.3e-32 110.5 0.0 1.2e-31 109.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Lon_2 PF13337.6 KIY70366.1 - 0.05 12.2 0.0 0.076 11.6 0.0 1.2 1 0 0 1 1 1 0 Putative ATP-dependent Lon protease Peroxin-3 PF04882.12 KIY70367.1 - 2.1e-82 277.6 0.4 2.3e-81 274.2 0.4 2.0 1 1 0 1 1 1 1 Peroxin-3 PQQ_3 PF13570.6 KIY70368.1 - 0.039 14.5 0.2 0.17 12.4 0.2 2.1 1 0 0 1 1 1 0 PQQ-like domain Secretin_N_2 PF07655.13 KIY70368.1 - 0.1 13.2 7.7 0.23 12.0 7.7 1.6 1 0 0 1 1 1 0 Secretin N-terminal domain Serglycin PF04360.12 KIY70368.1 - 0.41 10.6 13.3 1.7 8.6 13.3 1.9 1 1 0 1 1 1 0 Serglycin RAP1 PF07218.11 KIY70368.1 - 8.2 4.6 7.8 11 4.1 7.8 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) BUD22 PF09073.10 KIY70369.1 - 0.093 12.1 5.8 0.092 12.1 5.8 1.1 1 0 0 1 1 1 0 BUD22 SPX PF03105.19 KIY70369.1 - 0.19 11.6 7.9 0.18 11.7 7.9 1.1 1 0 0 1 1 1 0 SPX domain DUF4614 PF15391.6 KIY70369.1 - 0.33 10.9 15.0 0.49 10.4 15.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) SOG2 PF10428.9 KIY70369.1 - 1.6 7.9 16.9 1.8 7.7 16.9 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein Tmemb_cc2 PF10267.9 KIY70369.1 - 2.5 7.2 8.3 3 6.9 8.3 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein PAP1 PF08601.10 KIY70369.1 - 4.6 6.9 19.2 5.3 6.7 19.2 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 Apt1 PF10351.9 KIY70369.1 - 6.1 5.6 15.7 7.7 5.3 15.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 KIY70369.1 - 7.8 4.9 16.2 9.8 4.6 16.2 1.1 1 0 0 1 1 1 0 Macoilin family ATF7IP_BD PF16788.5 KIY70369.1 - 8 6.5 12.0 13 5.8 12.0 1.3 1 0 0 1 1 1 0 ATF-interacting protein binding domain p450 PF00067.22 KIY70370.1 - 1.5e-68 231.7 0.0 2.1e-68 231.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 ubiquitin PF00240.23 KIY70371.1 - 0.00012 21.8 0.0 0.00017 21.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KIY70371.1 - 0.00024 20.9 0.0 0.00037 20.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like SCP2 PF02036.17 KIY70371.1 - 0.013 16.0 0.0 0.02 15.4 0.0 1.3 1 0 0 1 1 1 0 SCP-2 sterol transfer family TUG-UBL1 PF11470.8 KIY70371.1 - 0.069 13.4 0.0 0.22 11.8 0.0 1.8 2 0 0 2 2 2 0 TUG ubiquitin-like domain Atg29_N PF18388.1 KIY70372.1 - 1.1e-13 50.8 1.4 1.1e-13 50.8 1.4 1.8 2 0 0 2 2 2 1 Atg29 N-terminal domain SMN PF06003.12 KIY70372.1 - 0.048 12.9 9.0 0.056 12.7 3.0 2.2 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) CobT PF06213.12 KIY70372.1 - 0.4 10.0 5.5 17 4.7 4.1 2.2 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT UPF0029 PF01205.19 KIY70373.1 - 1.4e-29 102.5 0.0 2.3e-29 101.8 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.22 KIY70373.1 - 2.9e-06 27.6 0.0 4.7e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 RWD domain UQ_con PF00179.26 KIY70373.1 - 0.082 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-conjugating enzyme Zn_clus PF00172.18 KIY70374.1 - 6.3e-05 23.0 6.7 0.00012 22.2 6.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KIY70374.1 - 0.0002 20.5 0.0 0.00032 19.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MoCF_biosynth PF00994.24 KIY70375.1 - 1.4e-59 199.8 0.1 3e-32 111.3 0.0 2.4 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.17 KIY70375.1 - 7.2e-36 123.3 0.4 1.2e-35 122.6 0.4 1.4 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.15 KIY70375.1 - 1.1e-14 54.4 0.0 2.5e-14 53.2 0.0 1.7 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) DASH_Spc19 PF08287.11 KIY70376.1 - 1.3e-20 73.9 1.4 5.7e-20 71.8 1.4 1.8 1 1 0 1 1 1 1 Spc19 TrkA_C PF02080.21 KIY70376.1 - 0.085 12.7 0.0 0.45 10.4 0.0 2.0 2 0 0 2 2 2 0 TrkA-C domain Myc-LZ PF02344.15 KIY70376.1 - 0.18 11.9 0.2 0.18 11.9 0.2 2.2 2 0 0 2 2 2 0 Myc leucine zipper domain Peptidase_S10 PF00450.22 KIY70377.1 - 1.7e-102 343.9 0.1 2.3e-102 343.5 0.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase stn_TNFRSF12A PF12191.8 KIY70377.1 - 0.12 12.6 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain TMEM51 PF15345.6 KIY70377.1 - 0.13 12.0 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein 51 TFIID-18kDa PF02269.16 KIY70378.1 - 1.4e-32 111.6 0.1 3.4e-32 110.3 0.1 1.7 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit TFIIE-A_C PF11521.8 KIY70378.1 - 0.023 15.0 1.3 0.051 13.9 1.3 1.7 1 0 0 1 1 1 0 C-terminal general transcription factor TFIIE alpha Adaptin_binding PF10199.9 KIY70378.1 - 0.077 13.6 1.1 0.15 12.7 1.1 1.5 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 S100PBPR PF15427.6 KIY70378.1 - 0.75 9.0 4.2 1.2 8.3 3.5 1.6 1 1 0 2 2 2 0 S100P-binding protein PI3_PI4_kinase PF00454.27 KIY70380.1 - 1.9e-46 158.9 0.0 3.6e-46 158.0 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 KIY70380.1 - 1.6e-33 116.3 0.4 1.6e-33 116.3 0.4 1.9 2 0 0 2 2 2 1 FAT domain UME PF08064.13 KIY70380.1 - 3.3e-18 65.5 0.7 1.4e-17 63.5 0.7 2.2 1 0 0 1 1 1 1 UME (NUC010) domain FATC PF02260.20 KIY70380.1 - 8.4e-08 31.9 0.0 2.6e-07 30.3 0.0 2.0 1 0 0 1 1 1 1 FATC domain HEAT PF02985.22 KIY70380.1 - 5.8e-06 26.1 0.2 0.042 14.1 0.0 5.2 5 0 0 5 5 5 1 HEAT repeat Cnd1 PF12717.7 KIY70380.1 - 2.8e-05 24.2 0.0 0.0021 18.1 0.0 3.0 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 DUF3385 PF11865.8 KIY70380.1 - 0.0011 19.0 0.0 0.0095 15.9 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3385) TIP120 PF08623.10 KIY70380.1 - 0.018 14.8 0.0 0.16 11.7 0.0 2.6 2 0 0 2 2 2 0 TATA-binding protein interacting (TIP20) HEAT_EZ PF13513.6 KIY70380.1 - 0.076 13.5 0.2 30 5.2 0.0 4.1 3 0 0 3 3 3 0 HEAT-like repeat Antimicrobial_2 PF08023.12 KIY70380.1 - 0.16 12.5 0.0 0.51 10.9 0.0 1.9 1 0 0 1 1 1 0 Frog antimicrobial peptide COX7a PF02238.15 KIY70381.1 - 9.6e-11 41.9 0.1 1.1e-10 41.7 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VII YEATS PF03366.16 KIY70382.1 - 1.5e-33 114.6 0.1 2.2e-33 114.0 0.1 1.3 1 0 0 1 1 1 1 YEATS family TPD52 PF04201.15 KIY70382.1 - 0.1 12.2 0.3 0.51 9.9 0.1 1.9 2 0 0 2 2 2 0 Tumour protein D52 family Thioredoxin_4 PF13462.6 KIY70383.1 - 1.9e-10 41.1 0.0 3.8e-10 40.2 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin zf-CHY PF05495.12 KIY70384.1 - 1.4e-13 51.1 17.5 2.7e-13 50.2 17.5 1.4 1 0 0 1 1 1 1 CHY zinc finger Cys_rich_KTR PF14205.6 KIY70384.1 - 7.3e-06 25.7 7.3 0.0019 18.0 2.2 2.8 2 1 1 3 3 3 2 Cysteine-rich KTR Zn_Tnp_IS1595 PF12760.7 KIY70384.1 - 0.0083 16.1 9.4 0.57 10.2 6.0 2.5 2 0 0 2 2 2 2 Transposase zinc-ribbon domain HypA PF01155.19 KIY70384.1 - 0.012 15.6 1.8 0.012 15.6 1.8 2.2 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn-ribbon_8 PF09723.10 KIY70384.1 - 0.022 14.9 3.2 0.022 14.9 3.2 2.6 2 1 0 2 2 2 0 Zinc ribbon domain DUF3797 PF12677.7 KIY70384.1 - 0.039 13.9 4.5 0.56 10.1 0.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF3797) DpnI PF06044.12 KIY70384.1 - 0.5 10.0 6.4 4.2 7.0 2.4 2.2 1 1 1 2 2 2 0 Dam-replacing family C1_4 PF07975.12 KIY70384.1 - 0.56 10.5 13.0 1.3 9.3 0.6 3.1 1 1 2 3 3 3 0 TFIIH C1-like domain zinc_ribbon_4 PF13717.6 KIY70384.1 - 1 9.3 0.1 1 9.3 0.1 4.2 4 0 0 4 4 4 0 zinc-ribbon domain zinc_ribbon_2 PF13240.6 KIY70384.1 - 2.9 7.7 12.5 2.3 8.0 0.4 3.2 3 0 0 3 3 3 0 zinc-ribbon domain Evr1_Alr PF04777.13 KIY70384.1 - 3.1 8.3 9.2 23 5.6 9.2 2.4 1 1 0 1 1 1 0 Erv1 / Alr family zinc_ribbon_9 PF14369.6 KIY70384.1 - 3.2 8.1 12.6 0.31 11.3 2.9 3.0 2 2 1 3 3 3 0 zinc-ribbon Zn_Tnp_IS91 PF14319.6 KIY70384.1 - 6.3 6.9 14.0 7.7 6.6 2.5 2.3 1 1 1 2 2 2 0 Transposase zinc-binding domain DUF4379 PF14311.6 KIY70384.1 - 6.5 7.2 12.5 0.57 10.6 0.6 2.6 3 0 0 3 3 3 0 Probable Zinc-ribbon domain zf-H2C2_2 PF13465.6 KIY70384.1 - 7.1 7.2 11.5 2.9 8.5 0.3 3.4 3 1 0 3 3 3 0 Zinc-finger double domain CDC14 PF08045.11 KIY70385.1 - 2.1e-31 109.1 0.0 3.2e-26 92.1 0.0 2.5 2 1 0 2 2 2 2 Cell division control protein 14, SIN component SPX PF03105.19 KIY70385.1 - 0.079 12.9 5.8 0.11 12.4 5.8 1.2 1 0 0 1 1 1 0 SPX domain CytochromB561_N PF09786.9 KIY70385.1 - 0.15 11.0 7.9 0.17 10.8 7.9 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal CNH PF00780.22 KIY70389.1 - 0.0065 16.1 0.0 0.15 11.6 0.0 2.2 2 0 0 2 2 2 1 CNH domain PH_9 PF15410.6 KIY70389.1 - 0.088 13.2 0.0 0.39 11.1 0.0 1.9 2 0 0 2 2 2 0 Pleckstrin homology domain TRP PF06011.12 KIY70390.1 - 1.2e-29 103.3 11.0 3.6e-29 101.7 11.0 1.7 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel E1_DerP2_DerF2 PF02221.15 KIY70390.1 - 0.032 14.7 0.0 0.06 13.8 0.0 1.5 1 0 0 1 1 1 0 ML domain DUF2973 PF11189.8 KIY70390.1 - 0.096 12.8 0.0 0.31 11.1 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2973) COesterase PF00135.28 KIY70392.1 - 2.9e-66 224.4 1.8 6.4e-66 223.3 1.8 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KIY70392.1 - 4.1e-06 26.8 0.4 0.02 14.8 0.1 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold Bacillus_HBL PF05791.11 KIY70393.1 - 0.062 13.1 2.2 0.11 12.4 1.3 1.8 1 1 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) DUF5082 PF16888.5 KIY70393.1 - 0.55 10.5 8.6 1.3 9.3 8.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) RasGAP_C PF03836.15 KIY70393.1 - 0.75 9.9 7.7 0.65 10.2 1.3 2.5 1 1 1 2 2 2 0 RasGAP C-terminus OmpH PF03938.14 KIY70393.1 - 0.89 9.9 21.2 1.9 8.9 3.2 2.8 1 1 2 3 3 3 0 Outer membrane protein (OmpH-like) NPV_P10 PF05531.12 KIY70393.1 - 2 8.9 7.8 0.96 10.0 2.8 3.0 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein IF2_N PF04760.15 KIY70394.1 - 0.16 11.8 0.1 0.65 9.9 0.0 1.9 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region Aha1_N PF09229.11 KIY70395.1 - 4.5e-30 104.6 0.0 6.8e-30 104.1 0.0 1.3 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 KIY70395.1 - 2.9e-15 56.6 0.3 7.3e-14 52.1 0.0 2.5 3 0 0 3 3 3 1 Activator of Hsp90 ATPase homolog 1-like protein Pox_Ag35 PF03286.14 KIY70396.1 - 0.11 12.3 4.2 0.15 11.8 4.2 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein FAM176 PF14851.6 KIY70396.1 - 1.5 8.4 4.5 1.2 8.8 2.7 1.7 2 0 0 2 2 2 0 FAM176 family F-box-like PF12937.7 KIY70398.1 - 0.021 14.7 2.1 0.077 12.9 2.1 2.0 1 1 0 1 1 1 0 F-box-like LRR_4 PF12799.7 KIY70398.1 - 0.069 13.6 0.3 71 4.0 0.0 4.1 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) PLA2_B PF01735.18 KIY70399.1 - 3.3e-109 365.5 0.0 4.5e-109 365.1 0.0 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Acetyltransf_1 PF00583.25 KIY70400.1 - 6.8e-14 52.1 0.0 8e-14 51.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KIY70400.1 - 6.8e-10 39.2 0.0 9.4e-10 38.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KIY70400.1 - 7.6e-10 38.8 0.0 9.1e-10 38.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIY70400.1 - 2.3e-07 30.7 0.0 3.3e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_15 PF17013.5 KIY70400.1 - 0.015 14.7 0.1 0.02 14.3 0.1 1.2 1 0 0 1 1 1 0 Putative acetyl-transferase Acetyltransf_4 PF13420.7 KIY70400.1 - 0.021 15.0 0.0 0.2 11.8 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain DUF4407 PF14362.6 KIY70401.1 - 0.0067 15.8 2.5 0.008 15.6 1.5 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4407) COG5 PF10392.9 KIY70401.1 - 0.01 16.0 0.5 0.02 15.1 0.5 1.3 1 0 0 1 1 1 0 Golgi transport complex subunit 5 HR1 PF02185.16 KIY70401.1 - 0.17 12.0 5.9 1.8 8.7 0.4 3.4 3 2 1 4 4 4 0 Hr1 repeat APG6_N PF17675.1 KIY70401.1 - 0.27 11.8 8.5 0.7 10.4 8.5 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region SpecificRecomb PF10136.9 KIY70401.1 - 0.37 9.0 1.0 0.48 8.7 1.0 1.1 1 0 0 1 1 1 0 Site-specific recombinase HIP1_clath_bdg PF16515.5 KIY70401.1 - 1.1 9.9 8.4 0.81 10.3 0.6 2.3 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 SlyX PF04102.12 KIY70401.1 - 1.3 9.7 5.5 44 4.8 0.2 3.6 2 1 0 2 2 2 0 SlyX PLA2_B PF01735.18 KIY70403.1 - 5.9e-104 348.2 0.0 8.5e-104 347.7 0.0 1.2 1 0 0 1 1 1 1 Lysophospholipase catalytic domain zf-RING_14 PF17978.1 KIY70403.1 - 0.069 13.6 0.0 0.14 12.6 0.0 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FAD_binding_3 PF01494.19 KIY70404.1 - 6.1e-21 75.1 0.3 1.5e-20 73.7 0.3 1.6 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KIY70404.1 - 0.00047 19.9 0.4 0.00071 19.3 0.1 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KIY70404.1 - 0.0011 19.2 0.6 0.004 17.4 0.3 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KIY70404.1 - 0.0033 16.7 0.6 0.094 11.9 0.6 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 KIY70404.1 - 0.011 14.8 0.0 0.017 14.2 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase Lycopene_cycl PF05834.12 KIY70404.1 - 0.042 12.9 1.1 0.41 9.6 0.1 2.3 2 1 0 2 2 2 0 Lycopene cyclase protein Thi4 PF01946.17 KIY70404.1 - 0.23 10.7 0.3 0.51 9.5 0.2 1.6 2 0 0 2 2 2 0 Thi4 family Trp_halogenase PF04820.14 KIY70404.1 - 0.23 10.3 1.7 0.26 10.1 0.2 1.8 3 0 0 3 3 3 0 Tryptophan halogenase KTI12 PF08433.10 KIY70406.1 - 6.1e-76 255.5 0.0 6.7e-76 255.3 0.0 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 KIY70406.1 - 1.6e-14 54.3 0.1 3.8e-14 53.1 0.1 1.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KIY70406.1 - 0.00087 19.8 0.0 0.0015 19.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain Mit_ribos_Mrp51 PF11709.8 KIY70408.1 - 1.7e-13 50.9 1.7 3.3e-12 46.7 0.6 2.9 2 1 0 2 2 2 1 Mitochondrial ribosomal protein subunit FAD_binding_3 PF01494.19 KIY70410.1 - 7.2e-22 78.1 0.0 5.7e-21 75.2 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KIY70410.1 - 5.9e-05 23.2 0.5 0.00018 21.7 0.5 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 KIY70410.1 - 0.00084 18.3 0.0 0.0014 17.6 0.0 1.5 1 0 0 1 1 1 1 Tryptophan halogenase HI0933_like PF03486.14 KIY70410.1 - 0.0054 15.5 1.2 0.28 9.8 0.7 2.1 2 0 0 2 2 2 1 HI0933-like protein Amino_oxidase PF01593.24 KIY70410.1 - 0.0087 15.4 0.4 0.28 10.4 0.0 2.5 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 KIY70410.1 - 0.032 13.4 0.0 0.65 9.2 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIY70410.1 - 0.038 13.6 0.6 0.066 12.8 0.6 1.6 1 1 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KIY70410.1 - 0.048 13.7 0.1 1.2 9.1 0.1 2.6 1 1 0 1 1 1 0 FAD-NAD(P)-binding Thi4 PF01946.17 KIY70410.1 - 0.049 12.9 0.3 0.1 11.8 0.3 1.5 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 KIY70410.1 - 0.11 13.1 0.1 20 5.8 0.4 3.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Chs7 PF12271.8 KIY70412.1 - 1.4e-75 254.4 5.4 1.6e-75 254.2 5.4 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone DUF3464 PF11947.8 KIY70412.1 - 0.47 10.2 2.2 1.1 9.0 2.2 1.7 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Cpta_toxin PF07254.12 KIY70412.1 - 1.5 8.8 5.1 3.2 7.8 5.1 1.7 1 1 0 1 1 1 0 Membrane-bound toxin component of toxin-antitoxin system COPI_assoc PF08507.10 KIY70413.1 - 0.47 10.5 6.4 0.39 10.8 0.9 2.1 2 0 0 2 2 2 0 COPI associated protein CD20 PF04103.15 KIY70413.1 - 0.52 10.4 4.5 0.17 12.0 0.7 2.1 2 0 0 2 2 2 0 CD20-like family FAD_binding_3 PF01494.19 KIY70414.1 - 6.6e-20 71.6 0.1 1.1e-10 41.3 0.1 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KIY70414.1 - 0.00096 19.3 1.1 0.0025 18.0 1.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 KIY70414.1 - 0.032 13.1 0.0 0.086 11.7 0.0 1.7 2 0 0 2 2 2 0 Tryptophan halogenase SE PF08491.10 KIY70414.1 - 0.05 12.6 0.0 0.086 11.9 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase Pyr_redox_2 PF07992.14 KIY70414.1 - 0.069 12.4 0.5 2.8 7.1 0.4 2.2 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Ribosomal_L37 PF08561.10 KIY70416.1 - 1.6e-16 60.9 10.3 2.5e-14 53.8 0.6 2.2 1 1 0 2 2 2 2 Mitochondrial ribosomal protein L37 CENP-C_C PF11699.8 KIY70417.1 - 1.9e-22 79.2 0.0 3.7e-22 78.3 0.0 1.5 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.11 KIY70417.1 - 0.0015 18.2 0.0 0.0031 17.2 0.0 1.6 1 0 0 1 1 1 1 Cupin domain tRNA_Me_trans PF03054.16 KIY70418.1 - 1.2e-108 363.1 0.0 1.4e-108 362.8 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase NAD_synthase PF02540.17 KIY70418.1 - 2.2e-07 30.2 0.0 0.00025 20.3 0.0 2.5 2 1 0 2 2 2 2 NAD synthase ATP_bind_3 PF01171.20 KIY70418.1 - 0.022 14.5 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 PP-loop family Asn_synthase PF00733.21 KIY70418.1 - 0.13 11.9 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Asparagine synthase QueC PF06508.13 KIY70418.1 - 0.18 11.2 0.0 1.6 8.2 0.0 2.0 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC Apt1 PF10351.9 KIY70419.1 - 0.12 11.2 4.8 0.12 11.2 4.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain CCDC24 PF15669.5 KIY70419.1 - 0.48 10.3 5.0 0.72 9.7 5.0 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family Macoilin PF09726.9 KIY70419.1 - 0.49 8.9 5.0 0.48 8.9 5.0 1.1 1 0 0 1 1 1 0 Macoilin family DUF3123 PF11321.8 KIY70419.1 - 1.7 9.4 7.4 0.15 12.7 0.8 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3123) CCDC106 PF15794.5 KIY70419.1 - 2.6 7.7 6.0 3.9 7.1 6.0 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 F-box-like PF12937.7 KIY70420.1 - 1.9e-07 30.9 0.1 7.9e-07 28.9 0.1 2.2 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KIY70420.1 - 0.071 13.6 0.1 1.5e+02 3.0 0.0 4.5 4 1 0 5 5 5 0 Leucine Rich repeats (2 copies) TPP_enzyme_N PF02776.18 KIY70422.1 - 1.5e-54 184.1 0.1 4.8e-54 182.6 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KIY70422.1 - 3e-47 160.2 0.1 3.7e-46 156.7 0.1 2.5 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KIY70422.1 - 8.9e-42 142.1 1.4 2.2e-41 140.8 0.5 2.1 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.19 KIY70422.1 - 0.052 13.3 0.0 0.095 12.4 0.0 1.4 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg SAPS PF04499.15 KIY70423.1 - 2.6e-116 389.3 0.0 3.3e-116 389.0 0.0 1.1 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein PAP_assoc PF03828.19 KIY70427.1 - 3.2e-17 62.5 0.1 9.4e-17 61.0 0.1 1.9 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KIY70427.1 - 1.8e-11 44.2 0.1 6.5e-10 39.2 0.0 2.5 2 0 0 2 2 2 1 Nucleotidyltransferase domain Polbeta PF18765.1 KIY70427.1 - 0.059 13.5 0.4 0.28 11.3 0.0 2.1 2 0 0 2 2 2 0 Polymerase beta, Nucleotidyltransferase Ank_2 PF12796.7 KIY70428.1 - 1.2e-05 25.9 0.0 2.7e-05 24.7 0.0 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KIY70428.1 - 2.2e-05 24.4 0.1 0.015 15.8 0.0 3.7 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 KIY70428.1 - 0.00034 20.9 0.1 0.22 11.9 0.0 3.5 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 KIY70428.1 - 0.023 15.1 0.0 0.23 12.0 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeat AMP-binding PF00501.28 KIY70429.1 - 2.2e-22 79.3 0.0 3.2e-22 78.7 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Thioesterase PF00975.20 KIY70429.1 - 1.7e-17 64.4 0.0 3e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain PP-binding PF00550.25 KIY70429.1 - 0.1 13.0 0.0 0.44 10.9 0.0 2.2 1 1 0 1 1 1 0 Phosphopantetheine attachment site AMP-binding PF00501.28 KIY70430.1 - 1.3e-22 80.1 0.1 2.3e-22 79.2 0.1 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Thioesterase PF00975.20 KIY70430.1 - 3.6e-16 60.0 0.0 6.1e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain PP-binding PF00550.25 KIY70430.1 - 0.0039 17.5 0.0 0.027 14.8 0.0 2.4 1 1 0 1 1 1 1 Phosphopantetheine attachment site Adap_comp_sub PF00928.21 KIY70431.1 - 9.4e-83 277.6 0.1 1.2e-82 277.2 0.1 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KIY70431.1 - 3.5e-07 30.3 2.8 6e-07 29.5 2.8 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF5618 PF18498.1 KIY70431.1 - 0.065 13.4 0.2 0.22 11.7 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5618) DUF11 PF01345.18 KIY70431.1 - 2.4 8.5 5.0 1.1 9.6 2.1 1.9 2 0 0 2 2 2 0 Domain of unknown function DUF11 FAA_hydrolase PF01557.18 KIY70434.1 - 9.3e-58 195.5 0.0 1.1e-57 195.2 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Herpes_glycop PF01528.16 KIY70435.1 - 0.0091 14.9 0.8 0.016 14.1 0.8 1.3 1 0 0 1 1 1 1 Herpesvirus glycoprotein M EphA2_TM PF14575.6 KIY70435.1 - 0.037 14.9 0.2 0.084 13.8 0.2 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Phage_Gp23 PF10669.9 KIY70435.1 - 0.064 13.6 0.0 0.097 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) DUF4834 PF16118.5 KIY70435.1 - 0.11 13.5 0.2 0.25 12.3 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) CD34_antigen PF06365.12 KIY70435.1 - 0.22 11.1 0.2 0.32 10.5 0.2 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family UreE_N PF02814.15 KIY70435.1 - 7.6 6.2 6.3 0.95 9.1 1.2 2.1 2 0 0 2 2 2 0 UreE urease accessory protein, N-terminal domain MGC-24 PF05283.11 KIY70436.1 - 0.0081 16.6 0.2 0.0081 16.6 0.2 2.2 2 1 0 2 2 2 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF2207 PF09972.9 KIY70436.1 - 0.02 13.7 0.0 0.028 13.2 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) SlyX PF04102.12 KIY70436.1 - 0.023 15.3 4.7 0.81 10.4 0.0 3.3 3 0 0 3 3 3 0 SlyX Gram_pos_anchor PF00746.21 KIY70436.1 - 0.1 12.6 1.3 0.26 11.3 1.3 1.8 1 0 0 1 1 1 0 LPXTG cell wall anchor motif DUF5305 PF17231.2 KIY70436.1 - 0.1 12.0 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) SOGA PF11365.8 KIY70436.1 - 0.31 12.2 1.3 0.56 11.4 1.3 1.4 1 0 0 1 1 1 0 Protein SOGA VPDSG-CTERM PF18205.1 KIY70436.1 - 0.7 9.8 4.1 2.3 8.1 4.1 2.0 1 0 0 1 1 1 0 VPDSG-CTERM motif TolA_bind_tri PF16331.5 KIY70436.1 - 1.1 9.3 7.2 7.8 6.7 0.1 2.3 2 0 0 2 2 2 0 TolA binding protein trimerisation RdRP_5 PF07925.11 KIY70436.1 - 1.2 6.4 3.2 0.63 7.4 0.3 1.7 2 0 0 2 2 2 0 Reovirus RNA-dependent RNA polymerase lambda 3 SnoaL PF07366.12 KIY70437.1 - 0.16 11.8 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase CENP-C_C PF11699.8 KIY70439.1 - 3.5e-20 72.0 0.0 7.6e-20 70.9 0.0 1.5 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.11 KIY70439.1 - 1.3e-09 37.6 0.0 4.1e-09 36.0 0.0 1.8 1 1 1 2 2 2 1 Cupin domain AraC_binding PF02311.19 KIY70439.1 - 3.3e-07 30.3 0.0 6.2e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_3 PF05899.12 KIY70439.1 - 0.0021 17.7 0.0 0.0042 16.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_1 PF00190.22 KIY70439.1 - 0.0031 17.1 0.0 0.0055 16.3 0.0 1.4 1 0 0 1 1 1 1 Cupin DUF1056 PF06341.11 KIY70439.1 - 0.0087 16.3 0.1 6.2 7.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1056) Cupin_6 PF12852.7 KIY70439.1 - 0.036 13.8 0.0 0.065 13.0 0.0 1.4 1 0 0 1 1 1 0 Cupin EutQ PF06249.12 KIY70439.1 - 0.22 11.3 0.0 0.38 10.5 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ Med3 PF11593.8 KIY70439.1 - 1.2 8.2 5.1 1.7 7.8 5.1 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Plavaka PF18759.1 KIY70442.1 - 5.4e-93 311.8 0.4 2.7e-92 309.4 0.4 2.0 1 1 0 1 1 1 1 Plavaka transposase zf-C2H2 PF00096.26 KIY70442.1 - 9.7 6.9 7.8 0.45 11.1 1.6 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF1771 PF08590.10 KIY70445.1 - 0.94 9.9 14.7 0.062 13.7 9.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1771) CE2_N PF17996.1 KIY70449.1 - 0.0018 18.3 0.1 3.2 7.8 0.0 3.1 2 1 0 2 2 2 2 Carbohydrate esterase 2 N-terminal FHA PF00498.26 KIY70452.1 - 1.4e-13 51.0 0.0 4.7e-13 49.3 0.0 1.9 1 0 0 1 1 1 1 FHA domain zf-RING_11 PF17123.5 KIY70452.1 - 1.8e-11 43.5 7.8 3.2e-11 42.8 7.8 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 KIY70452.1 - 1.9e-08 34.5 10.3 2.9e-08 33.9 10.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KIY70452.1 - 3.6e-05 23.5 10.4 5.7e-05 22.9 10.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIY70452.1 - 5e-05 23.1 9.9 8e-05 22.4 9.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KIY70452.1 - 0.00063 20.0 7.3 0.0013 18.9 7.3 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KIY70452.1 - 0.00079 19.4 2.0 0.0013 18.7 2.0 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 KIY70452.1 - 0.0018 18.2 8.6 0.003 17.5 8.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KIY70452.1 - 0.014 15.4 9.6 0.025 14.6 9.6 1.4 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KIY70452.1 - 0.016 15.4 1.8 0.035 14.3 1.8 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING PHD PF00628.29 KIY70452.1 - 0.044 13.7 5.2 0.082 12.8 5.2 1.4 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_3 PF13920.6 KIY70452.1 - 0.051 13.4 6.5 0.082 12.8 6.5 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KIY70452.1 - 0.18 11.4 4.9 0.3 10.7 4.9 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 KIY70452.1 - 0.81 9.6 8.2 1.4 8.8 8.2 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 CDC45 PF02724.14 KIY70452.1 - 7.4 4.7 8.3 11 4.2 8.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Trp_halogenase PF04820.14 KIY70453.1 - 0.00028 19.8 0.0 0.038 12.9 0.0 2.9 3 0 0 3 3 3 1 Tryptophan halogenase Endotoxin_mid PF09131.10 KIY70453.1 - 0.0029 17.3 0.1 0.0084 15.8 0.0 1.8 2 0 0 2 2 2 1 Bacillus thuringiensis delta-Endotoxin, middle domain Pyr_redox_2 PF07992.14 KIY70453.1 - 0.0099 15.1 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIY70453.1 - 0.064 12.8 0.0 1.3 8.5 0.0 2.2 1 1 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 KIY70453.1 - 0.1 13.2 0.0 0.2 12.2 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MDH PF02315.16 KIY70453.1 - 0.2 11.7 0.2 5.9 7.0 0.1 2.4 1 1 1 2 2 2 0 Methanol dehydrogenase beta subunit Rot1 PF10681.9 KIY70456.1 - 2.2e-42 144.9 0.8 2.5e-42 144.8 0.8 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal Myb_DNA-binding PF00249.31 KIY70459.1 - 5.4e-36 122.5 5.7 1.8e-11 44.0 0.8 3.7 4 0 0 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KIY70459.1 - 4.2e-24 84.5 0.7 1.2e-10 41.5 0.0 3.8 2 1 2 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KIY70459.1 - 0.00024 20.9 0.0 0.8 9.6 0.0 2.8 2 1 0 2 2 2 2 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 KIY70459.1 - 0.039 14.3 3.4 3 8.3 1.3 3.4 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_2 PF08914.11 KIY70459.1 - 0.064 13.4 0.2 4.1 7.6 0.0 2.7 2 1 0 2 2 2 0 Rap1 Myb domain G_path_suppress PF15991.5 KIY70459.1 - 1.2 9.2 3.6 1.8 8.6 3.6 1.2 1 0 0 1 1 1 0 G-protein pathway suppressor SR-25 PF10500.9 KIY70459.1 - 1.8 8.1 6.9 3.6 7.1 6.9 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Herpes_pp85 PF04637.12 KIY70459.1 - 5.3 5.3 5.4 7 4.9 5.4 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Chromo PF00385.24 KIY70461.1 - 5.2e-12 45.5 0.0 8.2e-12 44.9 0.0 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.8 KIY70461.1 - 0.32 10.9 3.6 0.4 10.6 1.0 2.5 2 1 0 2 2 2 0 RNA binding activity-knot of a chromodomain DUSP PF06337.12 KIY70464.1 - 0.097 13.3 0.1 0.52 11.0 0.0 2.2 2 0 0 2 2 2 0 DUSP domain DFRP_C PF16543.5 KIY70464.1 - 1.6 9.3 6.9 0.19 12.2 2.3 1.8 2 0 0 2 2 2 0 DRG Family Regulatory Proteins, Tma46 F-box-like PF12937.7 KIY70465.1 - 0.095 12.6 0.8 0.25 11.2 0.8 1.8 1 0 0 1 1 1 0 F-box-like PknH_C PF14032.6 KIY70466.1 - 0.032 14.1 3.1 0.047 13.5 2.7 1.6 1 1 0 1 1 1 0 PknH-like extracellular domain His_Phos_1 PF00300.22 KIY70467.1 - 7.7e-15 55.1 0.1 2.5e-14 53.5 0.1 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Histone PF00125.24 KIY70468.1 - 5.6e-17 62.3 0.0 6.8e-17 62.1 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 KIY70468.1 - 1.8e-16 59.6 1.2 3.5e-16 58.6 1.2 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 KIY70468.1 - 1.4e-06 28.5 0.0 1.8e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone O-FucT PF10250.9 KIY70469.1 - 1.1e-13 51.7 0.0 2.2e-12 47.4 0.0 2.5 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase MFS_1 PF07690.16 KIY70470.1 - 3.4e-26 92.0 33.7 1.1e-25 90.3 19.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 KIY70471.1 - 2.8e-40 138.4 36.9 2.8e-40 138.4 36.9 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIY70471.1 - 1e-05 24.6 25.6 0.00037 19.5 25.8 3.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_3 PF05977.13 KIY70471.1 - 0.0014 17.2 5.0 0.0014 17.2 5.0 2.0 2 0 0 2 2 2 1 Transmembrane secretion effector Metallophos PF00149.28 KIY70472.1 - 2e-36 126.4 0.0 2.7e-36 126.0 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 KIY70472.1 - 0.0053 16.4 0.0 0.0078 15.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain STPPase_N PF16891.5 KIY70472.1 - 0.013 15.9 0.6 0.034 14.6 0.6 1.7 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain ELYS PF13934.6 KIY70473.1 - 3.5e-40 138.3 0.6 4.8e-40 137.9 0.6 1.2 1 0 0 1 1 1 1 Nuclear pore complex assembly HpcH_HpaI PF03328.14 KIY70478.1 - 7.7e-30 103.7 0.0 1e-29 103.3 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PK PF00224.21 KIY70478.1 - 0.00053 19.0 0.1 0.0008 18.4 0.1 1.2 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain rhaM PF05336.13 KIY70478.1 - 0.066 13.3 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 L-rhamnose mutarotase DUF3581 PF12119.8 KIY70478.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3581) Aldo_ket_red PF00248.21 KIY70478.1 - 0.16 11.1 0.0 0.39 9.9 0.0 1.6 2 0 0 2 2 2 0 Aldo/keto reductase family Ctr PF04145.15 KIY70479.1 - 1.5e-35 123.0 2.8 1.8e-35 122.8 2.8 1.1 1 0 0 1 1 1 1 Ctr copper transporter family Vmethyltransf PF01660.17 KIY70479.1 - 0.05 12.5 0.1 0.065 12.1 0.1 1.1 1 0 0 1 1 1 0 Viral methyltransferase DUF2530 PF10745.9 KIY70479.1 - 0.052 13.8 1.5 0.055 13.7 0.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) Fungal_trans PF04082.18 KIY70480.1 - 2e-22 79.5 0.1 1.6e-21 76.5 0.0 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY70480.1 - 9e-09 35.3 8.3 1.6e-08 34.5 8.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.25 KIY70482.1 - 2.5e-45 154.9 0.0 3.6e-45 154.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY70482.1 - 2.4e-26 92.6 0.0 3.4e-26 92.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY70482.1 - 1.7e-05 24.3 0.0 0.0001 21.7 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KIY70482.1 - 0.0018 18.2 0.3 0.0063 16.5 0.3 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 KIY70482.1 - 0.0031 16.6 1.3 0.0042 16.1 0.1 1.7 2 0 0 2 2 2 1 Poxvirus serine/threonine protein kinase Kdo PF06293.14 KIY70482.1 - 0.1 11.9 0.1 0.16 11.3 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Transp_cyt_pur PF02133.15 KIY70484.1 - 1.4e-144 482.1 35.3 1.7e-144 481.9 35.3 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin MgtC PF02308.16 KIY70484.1 - 0.57 10.6 5.1 14 6.1 0.0 3.3 2 1 1 3 3 3 0 MgtC family PSI_PsaJ PF01701.18 KIY70484.1 - 1.6 9.3 5.4 7.3 7.2 0.8 3.9 3 0 0 3 3 3 0 Photosystem I reaction centre subunit IX / PsaJ Raf1_HTH PF18579.1 KIY70485.1 - 0.14 11.8 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 Rubisco accumulation factor 1 helix turn helix domain SMYLE_N PF18615.1 KIY70489.1 - 0.14 11.7 4.2 0.25 10.9 4.2 1.3 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain FAM176 PF14851.6 KIY70489.1 - 1 9.0 6.1 3.1 7.5 6.1 1.8 1 0 0 1 1 1 0 FAM176 family Use1 PF09753.9 KIY70489.1 - 4.7 6.9 8.8 8.3 6.0 8.8 1.3 1 0 0 1 1 1 0 Membrane fusion protein Use1 FGF-BP1 PF06473.12 KIY70489.1 - 8.7 6.1 14.3 0.8 9.5 0.3 2.2 2 0 0 2 2 2 0 FGF binding protein 1 (FGF-BP1) MFS_1 PF07690.16 KIY70492.1 - 1e-20 74.0 46.9 1.2e-20 73.8 39.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Zn_clus PF00172.18 KIY70494.1 - 0.0012 18.9 9.8 0.0022 18.1 9.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4195 PF13836.6 KIY70496.1 - 0.085 13.0 1.4 0.14 12.2 1.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4195) MFS_1 PF07690.16 KIY70497.1 - 1.5e-19 70.1 66.5 1.7e-18 66.7 32.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4239 PF14023.6 KIY70497.1 - 0.32 10.7 2.0 0.3 10.8 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4239) DDE_Tnp_4 PF13359.6 KIY70502.1 - 1.4e-06 28.1 0.0 2.1e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Nop14 PF04147.12 KIY70502.1 - 0.014 13.6 1.1 0.018 13.3 1.1 1.1 1 0 0 1 1 1 0 Nop14-like family CCSAP PF15748.5 KIY70502.1 - 0.038 14.2 5.3 0.06 13.5 5.3 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Sigma70_ner PF04546.13 KIY70502.1 - 0.06 13.2 2.4 0.091 12.6 1.6 1.6 2 0 0 2 2 2 0 Sigma-70, non-essential region SR-25 PF10500.9 KIY70502.1 - 0.12 12.0 7.7 0.18 11.4 7.7 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CCDC106 PF15794.5 KIY70502.1 - 0.22 11.2 2.7 0.3 10.8 1.5 1.7 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 Cwf_Cwc_15 PF04889.12 KIY70502.1 - 1.5 8.5 10.0 2.5 7.8 10.0 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein JAKMIP_CC3 PF16034.5 KIY70502.1 - 1.6 8.6 7.8 0.28 11.1 3.7 1.6 2 0 0 2 2 2 0 JAKMIP CC3 domain RRM_1 PF00076.22 KIY70506.1 - 1.1e-12 47.6 0.0 1.8e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 KIY70506.1 - 0.00031 21.2 0.0 0.00057 20.4 0.0 1.4 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 RRM_occluded PF16842.5 KIY70506.1 - 0.01 15.6 0.0 0.022 14.6 0.0 1.5 1 0 0 1 1 1 0 Occluded RNA-recognition motif 6PF2K PF01591.18 KIY70507.1 - 2.4e-59 200.3 0.0 4.4e-59 199.5 0.0 1.4 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KIY70507.1 - 1.6e-23 83.5 0.0 8.8e-19 68.0 0.0 2.5 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) KTI12 PF08433.10 KIY70507.1 - 0.0039 16.7 0.0 0.007 15.9 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 KIY70507.1 - 0.0047 17.1 0.0 0.012 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.20 KIY70507.1 - 0.11 12.3 0.1 0.2 11.5 0.1 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase Toprim_3 PF13362.6 KIY70507.1 - 0.14 12.6 0.0 0.35 11.3 0.0 1.6 1 0 0 1 1 1 0 Toprim domain DUF5381 PF17353.2 KIY70508.1 - 9.5 5.9 9.6 0.2 11.4 0.2 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF5381) MFS_1 PF07690.16 KIY70509.1 - 1.8e-19 69.9 59.2 4.7e-18 65.2 26.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily N_methyl PF07963.12 KIY70509.1 - 0.058 13.0 0.2 0.058 13.0 0.2 2.2 2 0 0 2 2 2 0 Prokaryotic N-terminal methylation motif MFS_1 PF07690.16 KIY70510.1 - 4.2e-20 72.0 40.6 8.1e-16 57.9 12.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MHYT PF03707.16 KIY70510.1 - 7.2 6.9 12.6 6.6 7.0 0.5 4.2 4 0 0 4 4 4 0 Bacterial signalling protein N terminal repeat Acetyltransf_1 PF00583.25 KIY70512.1 - 3.4e-10 40.2 0.0 4.3e-10 39.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KIY70512.1 - 3.9e-07 30.4 0.1 5.6e-07 29.9 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KIY70512.1 - 1.4e-05 25.1 0.0 2.1e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIY70512.1 - 6.5e-05 22.8 0.1 0.00013 21.8 0.1 1.6 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 KIY70512.1 - 9.8e-05 23.1 0.0 0.00012 22.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 KIY70512.1 - 0.0064 16.5 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase Acetyltransf_1 PF00583.25 KIY70513.1 - 1.1e-06 28.8 0.0 1.4e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_13 PF13880.6 KIY70513.1 - 0.00012 21.9 0.0 0.00026 20.9 0.0 1.4 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase Acetyltransf_7 PF13508.7 KIY70513.1 - 0.00013 22.3 0.0 0.00019 21.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KIY70513.1 - 0.0041 17.8 0.1 0.006 17.3 0.1 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIY70513.1 - 0.026 14.5 0.0 0.056 13.4 0.0 1.5 1 1 0 1 1 1 0 FR47-like protein Acetyltransf_15 PF17013.5 KIY70513.1 - 0.046 13.2 0.0 0.047 13.1 0.0 1.1 1 0 0 1 1 1 0 Putative acetyl-transferase Acetyltransf_10 PF13673.7 KIY70513.1 - 0.09 12.7 0.0 0.14 12.1 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KIY70513.1 - 0.099 12.7 0.0 0.37 10.9 0.0 2.0 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Glyco_transf_8 PF01501.20 KIY70515.1 - 1.8e-14 53.9 0.0 3.9e-14 52.8 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 8 Glyco_transf_24 PF18404.1 KIY70515.1 - 0.00069 19.1 0.0 0.001 18.6 0.0 1.2 1 0 0 1 1 1 1 Glucosyltransferase 24 MFS_1 PF07690.16 KIY70516.1 - 6e-26 91.2 50.1 1.1e-24 87.1 23.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4079 PF13301.6 KIY70516.1 - 0.26 11.4 4.6 0.89 9.7 0.8 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4079) LppA PF16708.5 KIY70517.1 - 0.11 12.4 0.2 0.21 11.5 0.2 1.4 1 0 0 1 1 1 0 Lipoprotein confined to pathogenic Mycobacterium Histone PF00125.24 KIY70519.1 - 4.4e-23 82.1 1.9 5.8e-23 81.7 1.9 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KIY70519.1 - 2.8e-05 24.3 1.2 3.7e-05 23.9 0.1 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KIY70519.1 - 0.00035 21.0 0.0 0.00055 20.4 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CENP-W PF15510.6 KIY70519.1 - 0.056 13.7 0.0 0.089 13.0 0.0 1.3 1 0 0 1 1 1 0 CENP-W protein Bt_P21 PF05560.11 KIY70519.1 - 0.097 12.3 0.1 0.12 12.0 0.1 1.2 1 0 0 1 1 1 0 Bacillus thuringiensis P21 molecular chaperone protein Histone PF00125.24 KIY70520.1 - 1.3e-16 61.2 0.0 1.6e-16 60.9 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 KIY70520.1 - 6.4e-16 57.8 1.5 1.2e-15 56.9 1.5 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 KIY70520.1 - 1.4e-06 28.5 0.0 1.9e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone MerT PF02411.15 KIY70521.1 - 0.018 15.1 0.1 0.043 13.8 0.1 1.7 1 0 0 1 1 1 0 MerT mercuric transport protein PMSR PF01625.21 KIY70528.1 - 7.6e-59 198.3 0.3 9.2e-59 198.0 0.3 1.1 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase AAA_lid_2 PF17863.1 KIY70529.1 - 0.011 15.5 0.2 0.031 14.1 0.2 1.7 1 0 0 1 1 1 0 AAA lid domain F-box-like PF12937.7 KIY70530.1 - 8.6e-07 28.8 0.2 3.1e-06 27.0 0.2 2.0 1 1 0 1 1 1 1 F-box-like Arrestin_C PF02752.22 KIY70533.1 - 2.7e-07 31.1 0.0 2.1e-05 25.0 0.0 2.7 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain RNase_PH PF01138.21 KIY70535.1 - 9.2e-12 45.6 0.5 1.7e-11 44.7 0.4 1.6 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KIY70535.1 - 6.3e-06 26.1 0.0 1.3e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 FAD_binding_2 PF00890.24 KIY70536.1 - 4.8e-126 421.2 2.6 6e-126 420.9 2.6 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 KIY70536.1 - 2.9e-41 140.4 0.4 4.3e-41 139.9 0.4 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 KIY70536.1 - 1.8e-05 24.2 0.5 0.0016 17.8 0.1 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KIY70536.1 - 2.6e-05 23.6 0.3 0.019 14.2 0.1 2.7 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.22 KIY70536.1 - 3.4e-05 23.1 1.3 0.0099 15.0 2.5 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_3 PF01494.19 KIY70536.1 - 0.0021 17.4 0.2 0.0038 16.5 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 KIY70536.1 - 0.003 16.7 0.0 0.0053 15.9 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.14 KIY70536.1 - 0.11 11.1 1.7 0.25 10.0 0.5 2.2 4 0 0 4 4 4 0 HI0933-like protein DAO PF01266.24 KIY70536.1 - 0.16 11.5 1.8 0.34 10.4 1.8 1.7 1 1 0 1 1 1 0 FAD dependent oxidoreductase F-box-like PF12937.7 KIY70538.1 - 0.036 14.0 0.6 0.036 14.0 0.6 2.6 2 0 0 2 2 2 0 F-box-like His_Me_b4a2 PF18275.1 KIY70538.1 - 1.3 9.1 4.7 0.91 9.6 1.9 2.1 2 0 0 2 2 2 0 His-Me finger endonuclease beta4-alpha2 domain MBOAT_2 PF13813.6 KIY70539.1 - 4.9e-16 58.8 4.6 4.9e-16 58.8 4.6 2.1 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family HATPase_c PF02518.26 KIY70540.1 - 3.3e-22 79.1 0.0 6.9e-22 78.1 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KIY70540.1 - 2e-17 63.3 0.1 5.3e-16 58.8 0.1 2.3 1 1 0 1 1 1 1 Response regulator receiver domain BRCT PF00533.26 KIY70540.1 - 0.16 12.4 0.0 0.58 10.6 0.0 2.0 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain zf-C3HC4 PF00097.25 KIY70541.1 - 7.4e-08 32.1 9.1 1.4e-07 31.3 9.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIY70541.1 - 4.9e-07 30.0 9.4 9.2e-07 29.1 9.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KIY70541.1 - 3.7e-06 26.7 7.3 6.6e-06 25.9 7.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIY70541.1 - 4.3e-06 26.6 8.4 7.7e-06 25.8 8.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KIY70541.1 - 8.5e-05 22.5 7.0 0.0002 21.3 7.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Prominin PF05478.11 KIY70541.1 - 0.0002 19.5 8.7 0.00025 19.1 8.7 1.1 1 0 0 1 1 1 1 Prominin Apolipoprotein PF01442.18 KIY70541.1 - 0.0022 17.9 17.5 0.12 12.3 0.0 2.2 1 1 1 2 2 2 1 Apolipoprotein A1/A4/E domain JIP_LZII PF16471.5 KIY70541.1 - 0.0065 16.6 7.2 0.008 16.3 3.0 2.6 2 0 0 2 2 2 1 JNK-interacting protein leucine zipper II zf-C3HC4_4 PF15227.6 KIY70541.1 - 0.0077 16.4 10.1 0.018 15.2 10.1 1.7 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING ADIP PF11559.8 KIY70541.1 - 0.0077 16.3 12.5 0.0077 16.3 12.5 2.2 1 1 1 2 2 2 1 Afadin- and alpha -actinin-Binding zf-C3HC4_2 PF13923.6 KIY70541.1 - 0.024 14.5 10.3 0.07 13.0 10.3 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PRKG1_interact PF15898.5 KIY70541.1 - 0.039 14.8 9.1 0.039 14.8 9.1 2.4 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain AAA_15 PF13175.6 KIY70541.1 - 0.044 13.5 4.2 0.057 13.1 4.2 1.2 1 0 0 1 1 1 0 AAA ATPase domain zf-RING_11 PF17123.5 KIY70541.1 - 0.053 13.3 5.3 0.12 12.1 5.3 1.7 1 0 0 1 1 1 0 RING-like zinc finger DUF3584 PF12128.8 KIY70541.1 - 0.064 10.8 18.4 0.082 10.4 18.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ATG16 PF08614.11 KIY70541.1 - 0.085 13.1 22.8 0.13 12.5 22.8 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Prok-RING_4 PF14447.6 KIY70541.1 - 0.15 12.0 7.6 0.31 10.9 7.6 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DUF4795 PF16043.5 KIY70541.1 - 0.16 11.6 13.5 1.5 8.4 7.4 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4795) ParB PF08775.10 KIY70541.1 - 0.17 12.4 10.7 0.26 11.8 1.6 2.3 1 1 1 2 2 2 0 ParB family ApoO PF09769.9 KIY70541.1 - 0.2 11.6 2.6 5.7 6.9 0.7 2.4 2 0 0 2 2 2 0 Apolipoprotein O Occludin_ELL PF07303.13 KIY70541.1 - 0.46 11.2 11.2 0.2 12.4 2.5 2.3 1 1 1 2 2 2 0 Occludin homology domain CASP_C PF08172.12 KIY70541.1 - 0.61 9.4 14.0 0.8 9.0 14.0 1.1 1 0 0 1 1 1 0 CASP C terminal DUF948 PF06103.11 KIY70541.1 - 0.68 10.2 6.8 9.1 6.6 1.2 2.5 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) APG6_N PF17675.1 KIY70541.1 - 0.75 10.3 21.5 2.1 8.9 11.7 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region OmpH PF03938.14 KIY70541.1 - 0.83 10.0 22.3 0.12 12.7 8.0 2.2 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Peptidase_S46 PF10459.9 KIY70541.1 - 1.1 7.9 15.7 0.17 10.5 5.2 2.0 1 1 1 2 2 2 0 Peptidase S46 TPR_MLP1_2 PF07926.12 KIY70541.1 - 1.4 9.0 24.7 10 6.2 22.6 2.7 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein V_ATPase_I PF01496.19 KIY70541.1 - 3.1 5.6 11.3 4.5 5.1 11.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family COMMD1_N PF17221.3 KIY70541.1 - 5.2 7.4 8.4 0.54 10.6 2.0 2.1 1 1 1 2 2 2 0 COMMD1 N-terminal domain Spc7 PF08317.11 KIY70541.1 - 6 5.7 18.8 8.9 5.1 18.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein YabA PF06156.13 KIY70541.1 - 6.4 7.5 16.4 10 6.8 3.0 2.8 1 1 1 2 2 2 0 Initiation control protein YabA NPV_P10 PF05531.12 KIY70541.1 - 8.4 6.9 10.1 4.8 7.7 2.9 3.0 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein zf-RING_UBOX PF13445.6 KIY70542.1 - 9e-10 38.4 2.5 9e-10 38.4 2.5 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KIY70542.1 - 1.1e-09 38.0 6.2 2.2e-09 37.0 6.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KIY70542.1 - 3.1e-09 36.5 7.5 1.1e-08 34.7 7.5 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIY70542.1 - 7.6e-09 35.8 7.4 1.9e-08 34.5 7.4 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KIY70542.1 - 9.2e-09 35.0 7.3 2.2e-08 33.8 7.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KIY70542.1 - 1.7e-08 34.5 8.9 1.7e-08 34.5 8.9 1.7 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 KIY70542.1 - 5.7e-08 32.6 6.5 1.2e-07 31.6 6.5 1.6 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KIY70542.1 - 2.4e-05 24.1 4.9 5.6e-05 22.9 4.9 1.6 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 KIY70542.1 - 0.0013 18.4 4.6 0.0041 16.8 4.6 1.9 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_4 PF14570.6 KIY70542.1 - 0.0042 16.8 6.7 0.011 15.5 6.7 1.8 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.6 KIY70542.1 - 0.011 15.6 6.7 0.024 14.5 6.7 1.7 1 1 0 1 1 1 0 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 KIY70542.1 - 0.056 13.7 4.4 0.19 12.1 4.4 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger domain NMD3 PF04981.13 KIY70542.1 - 0.22 10.9 3.0 0.2 11.1 1.8 1.4 1 1 0 1 1 1 0 NMD3 family HypA PF01155.19 KIY70542.1 - 0.29 11.2 3.6 0.48 10.5 0.2 2.4 2 1 0 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-RING_10 PF16685.5 KIY70542.1 - 2 8.6 8.2 2.1 8.5 4.9 2.2 2 0 0 2 2 2 0 zinc RING finger of MSL2 FYVE PF01363.21 KIY70542.1 - 4.6 7.5 10.2 1.6 8.9 4.9 2.9 2 1 0 2 2 2 0 FYVE zinc finger CDP-OH_P_transf PF01066.21 KIY70544.1 - 6.3e-14 52.5 1.0 6.3e-14 52.5 1.0 2.3 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF5632 PF18646.1 KIY70544.1 - 0.047 13.7 0.1 0.1 12.6 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5632) PACT_coil_coil PF10495.9 KIY70545.1 - 3e-17 63.0 0.0 3e-17 63.0 0.0 4.3 3 1 0 3 3 3 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein Matrilin_ccoil PF10393.9 KIY70545.1 - 3.4 7.6 9.5 6.1 6.8 0.1 4.8 5 0 0 5 5 5 0 Trimeric coiled-coil oligomerisation domain of matrilin Glyco_hydro_3_C PF01915.22 KIY70546.1 - 1.7e-63 214.3 0.0 2.7e-63 213.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KIY70546.1 - 2.5e-39 135.5 0.0 5.9e-39 134.3 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KIY70546.1 - 1.2e-24 86.2 0.1 2.7e-24 85.1 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 KIY70546.1 - 3.9e-11 43.0 0.0 8.6e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 PA14 domain DUF1752 PF08550.10 KIY70547.1 - 1.7e-07 30.9 10.2 1.7e-07 30.9 10.2 1.9 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1752) Hydrophobin PF01185.18 KIY70549.1 - 3e-10 40.6 7.1 4.9e-10 39.9 6.9 1.4 1 1 0 1 1 1 1 Fungal hydrophobin zf-RING_2 PF13639.6 KIY70551.1 - 7.4e-08 32.6 5.8 5.9e-07 29.7 2.4 2.2 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 KIY70551.1 - 8.9e-08 32.3 5.0 2.6e-07 30.8 5.0 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KIY70551.1 - 1.1e-06 28.4 0.2 2.1e-06 27.5 0.2 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KIY70551.1 - 6.5e-05 22.6 2.5 0.00056 19.6 0.1 2.3 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 KIY70551.1 - 0.00017 21.5 1.1 0.0003 20.7 1.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KIY70551.1 - 0.00031 20.7 0.7 0.00075 19.5 0.7 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KIY70551.1 - 0.00039 20.4 0.7 0.00069 19.6 0.7 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 KIY70551.1 - 0.00073 19.3 2.9 0.00076 19.3 0.8 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KIY70551.1 - 0.00085 18.9 0.8 0.0018 17.8 0.8 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 KIY70551.1 - 0.0011 18.8 6.7 0.0017 18.2 3.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KIY70551.1 - 0.0021 17.9 1.0 0.0021 17.9 1.0 1.8 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 RINGv PF12906.7 KIY70551.1 - 0.043 13.9 0.7 0.099 12.8 0.7 1.6 1 0 0 1 1 1 0 RING-variant domain DUF3565 PF12088.8 KIY70551.1 - 0.11 12.5 0.7 0.23 11.4 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3565) FANCL_C PF11793.8 KIY70551.1 - 0.28 11.4 2.6 0.9 9.8 2.6 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.11 KIY70551.1 - 0.42 10.9 1.8 0.74 10.2 1.8 1.4 1 0 0 1 1 1 0 RING-like domain zf-C3H2C3 PF17122.5 KIY70551.1 - 1.5 8.9 4.6 3.5 7.8 4.6 1.6 1 1 0 1 1 1 0 Zinc-finger zf-C3HC4_4 PF15227.6 KIY70551.1 - 2.3 8.4 4.1 0.4 10.9 0.6 1.6 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING HscB_4_cys PF18256.1 KIY70552.1 - 0.076 12.8 0.3 0.3 10.9 0.1 2.1 2 0 0 2 2 2 0 Co-chaperone HscB tetracysteine metal binding motif SGP PF17228.2 KIY70552.1 - 0.66 10.9 5.9 0.2 12.5 1.0 2.4 2 0 0 2 2 2 0 Sulphur globule protein Aminotran_5 PF00266.19 KIY70553.1 - 1.1e-17 64.1 0.1 2e-17 63.2 0.1 1.3 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KIY70553.1 - 5.5e-05 22.5 0.0 7.7e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KIY70553.1 - 0.11 11.7 0.6 0.54 9.5 0.6 1.8 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family SLATT_4 PF18186.1 KIY70554.1 - 0.45 10.1 5.1 0.11 12.1 1.0 1.9 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 4 TRIQK PF15168.6 KIY70554.1 - 0.46 10.4 4.3 7.8 6.5 0.0 3.1 3 0 0 3 3 3 0 Triple QxxK/R motif-containing protein family DUF456 PF04306.13 KIY70554.1 - 1.9 8.8 6.6 0.54 10.5 0.7 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF456) DUF1430 PF07242.11 KIY70554.1 - 2.5 8.4 8.2 4.8 7.5 1.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1430) zf-H2C2_2 PF13465.6 KIY70555.1 - 2.7e-09 37.0 14.3 1.8e-06 28.1 1.9 3.9 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 KIY70555.1 - 7.4e-09 35.6 17.1 0.00034 20.9 0.8 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 KIY70555.1 - 6.9e-06 25.7 9.1 0.00015 21.5 0.1 3.0 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KIY70555.1 - 0.21 11.9 2.4 2.2 8.6 1.4 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KIY70555.1 - 0.56 11.2 18.2 0.87 10.6 2.3 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-TRAF PF02176.18 KIY70555.1 - 0.57 10.9 8.8 1.3 9.7 0.7 2.3 2 0 0 2 2 2 0 TRAF-type zinc finger zf-met PF12874.7 KIY70555.1 - 3.6 8.1 8.3 0.55 10.7 0.5 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type ERG4_ERG24 PF01222.17 KIY70556.1 - 9.1e-129 430.0 23.8 1e-128 429.8 23.8 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 KIY70556.1 - 8.8e-05 22.1 5.6 8.8e-05 22.1 5.6 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) ICMT PF04140.14 KIY70556.1 - 0.054 13.9 1.7 0.085 13.3 0.1 2.2 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Lamprin PF06403.11 KIY70556.1 - 0.086 12.8 0.3 0.16 11.9 0.3 1.4 1 0 0 1 1 1 0 Lamprin MFS_1 PF07690.16 KIY70557.1 - 3.7e-33 114.9 34.8 5.2e-33 114.4 32.5 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF998 PF06197.13 KIY70557.1 - 2.2 7.8 23.0 0.53 9.8 10.2 3.6 2 2 0 2 2 2 0 Protein of unknown function (DUF998) AMP-binding PF00501.28 KIY70558.1 - 2.2e-74 250.6 0.4 2.2e-74 250.6 0.4 1.6 2 0 0 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.6 KIY70558.1 - 0.00013 22.9 0.8 0.00032 21.6 0.1 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Corona_NS3b PF03053.14 KIY70558.1 - 0.0017 18.1 1.7 0.0017 18.1 1.7 1.7 2 0 0 2 2 2 1 ORF3b coronavirus protein DUF4079 PF13301.6 KIY70558.1 - 0.041 14.0 2.8 0.039 14.1 1.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4079) FAD_binding_4 PF01565.23 KIY70559.1 - 3.1e-26 91.8 3.2 4.9e-26 91.1 3.2 1.3 1 0 0 1 1 1 1 FAD binding domain Peptidase_C15 PF01470.17 KIY70560.1 - 3.9e-11 43.5 0.0 3.4e-06 27.4 0.0 2.1 2 0 0 2 2 2 2 Pyroglutamyl peptidase Ribosomal_L18A PF01775.17 KIY70561.1 - 5e-56 188.0 0.7 6.2e-56 187.7 0.7 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A Questin_oxidase PF14027.6 KIY70562.1 - 5.7e-86 289.1 0.1 6.9e-86 288.9 0.1 1.1 1 0 0 1 1 1 1 Questin oxidase-like DUF4451 PF14616.6 KIY70563.1 - 0.00082 19.6 4.9 0.27 11.4 0.2 2.9 3 0 0 3 3 3 2 Domain of unknown function (DUF4451) KAR9 PF08580.10 KIY70565.1 - 2e-24 86.2 29.3 2e-24 86.2 29.3 2.8 2 2 0 2 2 2 1 Yeast cortical protein KAR9 GAS2 PF02187.17 KIY70565.1 - 0.00014 21.9 0.1 0.00081 19.4 0.0 2.1 2 0 0 2 2 2 1 Growth-Arrest-Specific Protein 2 Domain Hist_deacetyl PF00850.19 KIY70566.1 - 7.3e-57 193.2 0.0 9.6e-57 192.8 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain TAL_FSA PF00923.19 KIY70567.1 - 9.9e-44 149.8 0.1 1.2e-43 149.5 0.1 1.1 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase HTH_Tnp_Mu_2 PF09039.11 KIY70567.1 - 0.17 11.9 0.0 0.36 10.9 0.0 1.5 1 0 0 1 1 1 0 Mu DNA binding, I gamma subdomain Proteasome PF00227.26 KIY70568.1 - 5.3e-36 123.9 0.0 6.6e-36 123.6 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit MFS_1 PF07690.16 KIY70570.1 - 1.1e-17 64.1 54.1 7.9e-10 38.2 23.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MARVEL PF01284.23 KIY70571.1 - 0.001 19.1 12.9 0.0016 18.5 12.9 1.3 1 0 0 1 1 1 1 Membrane-associating domain COX1 PF00115.20 KIY70571.1 - 0.0097 14.8 7.4 0.011 14.6 7.1 1.3 1 1 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I DUF3318 PF11780.8 KIY70571.1 - 0.34 10.9 0.2 0.34 10.9 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3318) DUF5373 PF17343.2 KIY70571.1 - 0.44 10.4 2.1 0.61 9.9 0.8 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5373) DUF3040 PF11239.8 KIY70571.1 - 5.6 7.3 6.8 1.7 9.0 1.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3040) Phage_holin_1 PF04531.13 KIY70571.1 - 5.7 7.5 5.6 1.7 9.2 0.5 2.3 2 1 0 2 2 2 0 Bacteriophage holin TPR_19 PF14559.6 KIY70574.1 - 7.2e-05 23.2 1.6 0.36 11.4 0.3 2.7 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KIY70574.1 - 0.00012 22.6 1.2 0.53 11.0 2.4 3.0 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 KIY70574.1 - 0.0011 19.6 8.0 12 7.0 0.0 5.7 4 2 2 6 6 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KIY70574.1 - 0.011 15.9 0.2 6 7.2 0.0 2.6 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 KIY70574.1 - 0.022 14.9 2.6 1.2 9.4 0.5 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 KIY70574.1 - 0.058 13.7 0.3 15 5.9 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 KIY70574.1 - 0.082 12.8 0.0 0.83 9.6 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 KIY70574.1 - 0.12 12.5 0.1 43 4.6 0.1 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 KIY70574.1 - 0.13 12.8 0.3 3.1 8.4 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 KIY70574.1 - 0.18 12.1 0.0 19 5.8 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat CRIM PF16978.5 KIY70575.1 - 4.5e-41 140.3 0.2 1.8e-40 138.4 0.0 2.1 2 0 0 2 2 2 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1_PH PF16979.5 KIY70575.1 - 2.7e-31 108.1 0.1 4.8e-31 107.3 0.1 1.4 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology TUG-UBL1 PF11470.8 KIY70575.1 - 2.6e-05 24.4 0.0 5.5e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 TUG ubiquitin-like domain RBD PF02196.15 KIY70575.1 - 0.00058 19.9 0.0 0.0016 18.4 0.0 1.8 1 0 0 1 1 1 1 Raf-like Ras-binding domain RA PF00788.23 KIY70575.1 - 0.0012 19.4 0.0 0.012 16.2 0.0 2.3 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain Clr2_transil PF16761.5 KIY70576.1 - 2.3e-21 76.4 0.9 4.8e-21 75.4 0.9 1.6 1 0 0 1 1 1 1 Transcription-silencing protein, cryptic loci regulator Clr2 Clr2 PF10383.9 KIY70576.1 - 4.5e-13 50.2 0.0 1.5e-12 48.5 0.0 1.9 2 0 0 2 2 2 1 Transcription-silencing protein Clr2 PWWP PF00855.17 KIY70576.1 - 0.04 14.3 0.0 0.1 13.0 0.0 1.7 1 0 0 1 1 1 0 PWWP domain Ferritin_2 PF13668.6 KIY70577.1 - 1.6e-43 148.1 5.2 2.4e-43 147.6 5.2 1.3 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.17 KIY70577.1 - 0.051 14.0 1.5 0.21 12.0 1.3 2.0 1 1 1 2 2 2 0 Rubrerythrin Inv-AAD PF18785.1 KIY70578.1 - 1.5e-27 96.0 0.0 2e-27 95.6 0.0 1.1 1 0 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase dCMP_cyt_deam_1 PF00383.23 KIY70578.1 - 1.2e-16 60.5 0.2 1.8e-16 59.9 0.2 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KIY70578.1 - 7.9e-07 28.9 0.1 1e-06 28.6 0.1 1.3 1 0 0 1 1 1 1 MafB19-like deaminase APOBEC_N PF08210.11 KIY70578.1 - 0.0023 17.9 0.1 0.023 14.6 0.1 2.0 1 1 0 1 1 1 1 APOBEC-like N-terminal domain XOO_2897-deam PF14440.6 KIY70578.1 - 0.058 13.5 0.0 0.091 12.9 0.0 1.3 1 0 0 1 1 1 0 Xanthomonas XOO_2897-like deaminase WD40 PF00400.32 KIY70579.1 - 1.8e-20 72.9 18.3 0.0085 16.9 0.0 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KIY70579.1 - 0.0017 17.4 0.9 0.21 10.5 0.0 3.4 2 2 2 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIY70579.1 - 0.0023 16.7 2.5 2 6.9 0.1 3.4 2 1 1 3 3 3 3 Nucleoporin Nup120/160 MFS_1 PF07690.16 KIY70580.1 - 1.2e-11 44.1 40.1 1.2e-11 44.1 40.1 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.16 KIY70580.1 - 1.9e-05 24.4 10.2 1.9e-05 24.4 10.2 3.3 3 1 0 3 3 3 1 Ion channel regulatory protein UNC-93 p450 PF00067.22 KIY70581.1 - 2.2e-59 201.4 0.0 2.8e-59 201.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ABC2_membrane PF01061.24 KIY70581.1 - 0.13 11.7 0.0 0.26 10.7 0.0 1.5 1 0 0 1 1 1 0 ABC-2 type transporter Pkinase PF00069.25 KIY70582.1 - 1.6e-59 201.4 0.0 1.6e-58 198.1 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY70582.1 - 1.1e-23 83.9 0.4 3.4e-18 65.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 KIY70582.1 - 3.1e-05 23.1 0.0 5e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KIY70582.1 - 0.0062 16.5 1.0 0.39 10.6 0.4 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KIY70582.1 - 0.0099 15.2 1.3 0.038 13.3 0.2 2.4 2 1 0 2 2 2 1 Kinase-like Pkinase_C PF00433.24 KIY70582.1 - 0.015 16.0 0.0 0.036 14.8 0.0 1.7 1 0 0 1 1 1 0 Protein kinase C terminal domain Kdo PF06293.14 KIY70582.1 - 0.022 14.1 0.5 0.069 12.5 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KIY70582.1 - 0.034 12.9 0.0 0.067 12.0 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Seadorna_VP7 PF07387.11 KIY70582.1 - 0.051 12.6 0.0 0.095 11.7 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 D123 PF07065.14 KIY70583.1 - 3.5e-83 279.3 0.0 4.4e-83 278.9 0.0 1.0 1 0 0 1 1 1 1 D123 Helicase_C_2 PF13307.6 KIY70584.1 - 4.8e-53 179.8 0.0 1.5e-52 178.2 0.0 1.9 2 0 0 2 2 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 KIY70584.1 - 2.8e-43 147.6 0.0 3.2e-42 144.1 0.0 2.5 1 1 0 1 1 1 1 DEAD_2 ResIII PF04851.15 KIY70584.1 - 2.7e-05 24.2 0.0 0.0074 16.3 0.0 2.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit PhoH PF02562.16 KIY70584.1 - 0.00012 21.6 0.0 0.029 13.8 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein AAA_22 PF13401.6 KIY70584.1 - 0.00033 20.9 0.6 1.7 8.9 0.1 3.3 2 0 0 2 2 2 2 AAA domain DEAD PF00270.29 KIY70584.1 - 0.0024 17.7 0.1 0.058 13.2 0.0 2.5 3 0 0 3 3 3 1 DEAD/DEAH box helicase AAA_25 PF13481.6 KIY70584.1 - 0.012 15.2 0.1 0.046 13.3 0.1 2.0 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 KIY70584.1 - 0.037 13.1 1.4 0.067 12.2 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_30 PF13604.6 KIY70584.1 - 0.05 13.3 0.0 0.6 9.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KIY70584.1 - 0.11 12.9 0.4 1.2 9.5 0.2 2.7 1 1 0 1 1 1 0 AAA domain DUF3619 PF12279.8 KIY70584.1 - 2.2 8.6 7.3 0.29 11.5 2.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3619) SIR2 PF02146.17 KIY70585.1 - 6e-29 101.2 0.0 8.9e-29 100.7 0.0 1.3 1 0 0 1 1 1 1 Sir2 family Sugar_tr PF00083.24 KIY70586.1 - 9.5e-76 255.5 25.4 1.2e-75 255.1 25.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY70586.1 - 1.5e-14 53.7 42.4 1.6e-11 43.7 20.7 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily F-box-like PF12937.7 KIY70587.1 - 3e-08 33.4 2.4 9.3e-08 31.8 2.4 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY70587.1 - 0.012 15.5 2.4 3.3 7.7 0.0 2.7 2 0 0 2 2 2 0 F-box domain F-box-like_2 PF13013.6 KIY70587.1 - 0.039 13.9 0.4 0.093 12.7 0.4 1.7 1 0 0 1 1 1 0 F-box-like domain ZZ PF00569.17 KIY70588.1 - 4.8e-12 45.5 11.2 1e-07 31.7 7.0 2.2 2 0 0 2 2 2 2 Zinc finger, ZZ type C1_2 PF03107.16 KIY70588.1 - 1.4e-05 25.3 13.1 0.0043 17.3 8.9 2.2 2 0 0 2 2 2 2 C1 domain DUF3795 PF12675.7 KIY70588.1 - 0.0067 16.8 3.9 0.067 13.6 1.6 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3795) zf-B_box PF00643.24 KIY70588.1 - 0.96 9.7 9.5 8.5 6.6 3.3 2.8 3 0 0 3 3 3 0 B-box zinc finger Pantoate_ligase PF02569.15 KIY70589.1 - 9.6e-92 306.9 0.0 1.2e-91 306.6 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase Hormone_3 PF00159.18 KIY70589.1 - 0.019 15.0 0.1 0.037 14.1 0.1 1.5 1 0 0 1 1 1 0 Pancreatic hormone peptide Cript PF10235.9 KIY70590.1 - 4.8e-26 91.1 3.2 4.8e-26 91.1 3.2 1.5 1 1 1 2 2 2 1 Microtubule-associated protein CRIPT DZR PF12773.7 KIY70590.1 - 0.00041 20.3 2.6 0.00041 20.3 2.6 2.0 2 0 0 2 2 2 1 Double zinc ribbon DUF2039 PF10217.9 KIY70590.1 - 0.0032 17.8 5.7 0.0032 17.8 5.7 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2039) zinc_ribbon_2 PF13240.6 KIY70590.1 - 0.0095 15.6 9.8 4.8 7.0 4.5 3.2 3 0 0 3 3 3 2 zinc-ribbon domain Gin PF10764.9 KIY70590.1 - 0.01 15.8 7.3 0.35 10.9 0.0 3.2 2 1 0 3 3 3 0 Inhibitor of sigma-G Gin Rhodanese_C PF12368.8 KIY70590.1 - 0.045 14.1 7.1 0.08 13.3 2.7 2.1 2 0 0 2 2 2 0 Rhodanase C-terminal zf_UBZ PF18439.1 KIY70590.1 - 2.3 7.9 7.9 17 5.1 0.1 3.1 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger RhaA PF06134.11 KIY70591.1 - 0.053 12.6 0.0 0.085 12.0 0.0 1.2 1 0 0 1 1 1 0 L-rhamnose isomerase (RhaA) Methyltransf_16 PF10294.9 KIY70592.1 - 1.2e-19 70.7 0.0 1.6e-19 70.3 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 KIY70592.1 - 2e-06 27.5 0.0 3.3e-06 26.8 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase small domain GidB PF02527.15 KIY70592.1 - 3.6e-06 26.4 0.0 5.7e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G Methyltransf_31 PF13847.6 KIY70592.1 - 0.00032 20.5 0.0 0.0004 20.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIY70592.1 - 0.0011 19.7 0.0 0.0019 18.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIY70592.1 - 0.008 16.8 0.0 0.014 16.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIY70592.1 - 0.0085 16.8 0.0 0.014 16.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIY70592.1 - 0.016 15.0 0.0 0.039 13.8 0.0 1.5 1 1 1 2 2 2 0 Methyltransferase domain DUF938 PF06080.12 KIY70592.1 - 0.036 13.8 0.0 0.05 13.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF938) SNF2_N PF00176.23 KIY70594.1 - 1.2e-15 57.1 0.1 6.1e-12 44.9 0.0 2.6 2 0 0 2 2 2 2 SNF2 family N-terminal domain DNA_methylase PF00145.17 KIY70594.1 - 5.6e-15 55.5 0.0 5.6e-15 55.5 0.0 2.8 3 1 0 3 3 3 1 C-5 cytosine-specific DNA methylase ResIII PF04851.15 KIY70594.1 - 0.0016 18.5 0.1 0.011 15.8 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CTD_bind PF04818.13 KIY70595.1 - 0.00063 20.5 0.0 0.0018 19.0 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase II-binding domain. PET117 PF15786.5 KIY70596.1 - 2.4e-25 88.6 3.1 2.7e-25 88.4 3.1 1.0 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial DUF4006 PF13179.6 KIY70596.1 - 0.17 11.8 0.1 0.26 11.2 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF4006) Dicer_dimer PF03368.14 KIY70597.1 - 0.0028 17.8 0.1 0.015 15.4 0.0 2.2 2 0 0 2 2 2 1 Dicer dimerisation domain F-box-like PF12937.7 KIY70598.1 - 1.6e-06 27.9 0.2 1.6e-05 24.7 0.0 2.9 4 1 0 4 4 4 1 F-box-like Ank_2 PF12796.7 KIY70599.1 - 2.4e-11 44.1 0.1 4.7e-05 23.9 0.2 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KIY70599.1 - 1e-07 32.3 0.4 4.5e-05 23.9 0.2 3.3 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIY70599.1 - 1.1e-06 28.5 0.2 0.079 13.6 0.1 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 KIY70599.1 - 2.3e-06 27.8 5.5 0.00085 19.7 0.5 3.3 3 0 0 3 3 3 2 Ankyrin repeat KilA-N PF04383.13 KIY70599.1 - 0.00017 21.4 0.1 0.0055 16.5 0.1 2.5 1 1 0 1 1 1 1 KilA-N domain Ank_5 PF13857.6 KIY70599.1 - 0.0017 18.6 0.6 0.11 12.8 0.0 3.1 3 1 0 3 3 3 1 Ankyrin repeats (many copies) zf-MYND PF01753.18 KIY70600.1 - 2.9e-07 30.5 13.4 6.4e-07 29.3 13.4 1.6 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KIY70600.1 - 0.72 10.2 12.6 1.4 9.3 12.6 1.5 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Hexapep PF00132.24 KIY70603.1 - 3.6e-09 36.0 18.4 4.4e-08 32.5 2.0 4.0 4 1 0 5 5 5 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KIY70603.1 - 0.00022 20.9 10.2 0.00097 18.8 1.0 2.9 2 1 1 3 3 3 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 KIY70603.1 - 0.0026 16.7 0.1 0.0042 16.1 0.1 1.2 1 0 0 1 1 1 1 L-fucokinase adh_short_C2 PF13561.6 KIY70605.1 - 1.7e-48 165.2 0.1 2e-48 165.0 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIY70605.1 - 4.7e-37 127.3 0.0 6.4e-37 126.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIY70605.1 - 5.4e-05 23.2 0.1 7.7e-05 22.7 0.1 1.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KIY70605.1 - 0.00035 20.1 0.1 0.0025 17.3 0.0 2.2 3 0 0 3 3 3 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KIY70605.1 - 0.0027 17.2 0.0 0.0043 16.5 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KIY70605.1 - 0.066 12.3 0.0 0.099 11.8 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3HCDH_N PF02737.18 KIY70605.1 - 0.1 12.4 0.0 0.25 11.2 0.0 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 KIY70605.1 - 0.11 11.6 0.0 0.86 8.6 0.0 2.1 1 1 0 1 1 1 0 RmlD substrate binding domain Septin PF00735.18 KIY70606.1 - 3.4e-107 357.9 0.0 5.5e-107 357.2 0.0 1.3 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KIY70606.1 - 8.2e-06 25.9 0.0 1.7e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KIY70606.1 - 0.00041 19.9 1.4 0.0031 17.1 0.2 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KIY70606.1 - 0.0069 16.5 1.4 0.75 9.8 0.0 2.9 2 1 1 3 3 3 1 Dynamin family AIG1 PF04548.16 KIY70606.1 - 0.0077 15.6 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 AIG1 family AAA_33 PF13671.6 KIY70606.1 - 0.044 14.0 0.1 0.15 12.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 KIY70606.1 - 0.058 13.3 0.6 0.058 13.3 0.6 2.5 3 1 0 3 3 3 0 RsgA GTPase Roc PF08477.13 KIY70606.1 - 0.059 13.6 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase IIGP PF05049.13 KIY70606.1 - 0.083 11.9 0.3 0.23 10.5 0.1 1.7 1 1 0 2 2 2 0 Interferon-inducible GTPase (IIGP) Gasdermin_C PF17708.1 KIY70606.1 - 0.18 11.9 4.1 0.19 11.8 2.9 1.6 2 0 0 2 2 2 0 Gasdermin PUB domain YIF1 PF03878.15 KIY70607.1 - 1.3e-82 277.0 0.3 1.4e-82 276.8 0.3 1.0 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.17 KIY70607.1 - 0.0026 17.5 7.8 0.0057 16.4 7.7 1.6 1 1 0 1 1 1 1 Yip1 domain SPC12 PF06645.13 KIY70608.1 - 1.8e-28 98.4 2.6 2e-28 98.2 2.6 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) DUF3379 PF11859.8 KIY70608.1 - 0.21 10.9 0.4 0.23 10.8 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3379) F-box-like PF12937.7 KIY70609.1 - 4.5e-07 29.6 0.3 1.1e-06 28.4 0.3 1.7 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.6 KIY70609.1 - 0.0039 16.9 1.0 2.8 7.8 0.0 4.2 4 0 0 4 4 4 1 Leucine rich repeat LRR_4 PF12799.7 KIY70609.1 - 0.027 14.9 2.5 8.3 7.0 0.0 4.7 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) BAR PF03114.18 KIY70610.1 - 5.3e-51 173.6 0.1 6.2e-51 173.3 0.1 1.0 1 0 0 1 1 1 1 BAR domain LPD39 PF18858.1 KIY70610.1 - 0.0085 16.2 5.0 0.2 11.7 0.8 2.6 2 1 0 3 3 3 2 Large polyvalent protein associated domain 39 Arfaptin PF06456.13 KIY70610.1 - 0.024 14.2 1.6 0.26 10.8 1.6 2.2 1 1 0 1 1 1 0 Arfaptin-like domain SYF2 PF08231.12 KIY70610.1 - 0.028 14.8 2.0 0.051 14.0 1.9 1.6 1 1 0 1 1 1 0 SYF2 splicing factor IFT57 PF10498.9 KIY70610.1 - 0.06 12.3 0.0 0.11 11.4 0.0 1.4 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Glyco_hydro_61 PF03443.14 KIY70611.1 - 5.9e-50 170.1 0.2 1.1e-49 169.1 0.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 SOG2 PF10428.9 KIY70611.1 - 0.28 10.3 13.0 0.35 10.0 13.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein PRCC PF10253.9 KIY70611.1 - 3.6 8.3 13.0 5.7 7.7 13.0 1.3 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting RIBIOP_C PF04950.12 KIY70613.1 - 1.5e-118 395.4 0.0 2.5e-118 394.8 0.0 1.3 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 KIY70613.1 - 1.5e-17 63.5 0.0 1.1e-16 60.7 0.0 2.3 1 1 0 1 1 1 1 AARP2CN (NUC121) domain DUF2205 PF10224.9 KIY70615.1 - 0.64 10.0 5.8 0.31 11.0 2.2 2.4 2 0 0 2 2 2 0 Short coiled-coil protein EMP24_GP25L PF01105.24 KIY70615.1 - 2.8 7.8 4.0 6.8 6.6 4.0 1.6 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD PIG-U PF06728.13 KIY70616.1 - 4.7e-99 332.0 28.7 5.5e-99 331.8 28.7 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Big_7 PF17957.1 KIY70617.1 - 0.029 15.2 1.5 0.056 14.2 1.5 1.8 1 1 0 1 1 1 0 Bacterial Ig domain A2M PF00207.22 KIY70617.1 - 0.041 13.7 0.0 0.56 10.1 0.0 2.1 2 0 0 2 2 2 0 Alpha-2-macroglobulin family BioY PF02632.14 KIY70617.1 - 0.059 13.4 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 BioY family Fn3-like PF14310.6 KIY70617.1 - 0.15 12.2 0.0 0.54 10.4 0.0 1.8 2 0 0 2 2 2 0 Fibronectin type III-like domain F-box-like PF12937.7 KIY70618.1 - 1.6e-05 24.7 0.6 4e-05 23.4 0.6 1.7 1 0 0 1 1 1 1 F-box-like zf-C2H2 PF00096.26 KIY70619.1 - 8.7e-09 35.4 11.4 0.00032 21.0 1.0 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIY70619.1 - 7.8e-06 26.3 9.8 0.024 15.5 0.5 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KIY70619.1 - 1.3e-05 25.4 2.4 0.11 12.8 1.0 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KIY70619.1 - 0.00037 20.4 3.4 0.098 12.7 0.1 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 KIY70619.1 - 0.004 17.5 3.5 1.2 9.6 0.0 2.8 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf_UBZ PF18439.1 KIY70619.1 - 0.016 14.8 5.8 0.79 9.4 0.6 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 KIY70619.1 - 0.016 15.3 5.1 0.045 13.9 5.1 1.7 1 1 0 1 1 1 0 Zinc ribbon domain zf-LYAR PF08790.11 KIY70619.1 - 0.041 13.8 4.8 0.59 10.1 0.8 2.6 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger Terminase_GpA PF05876.12 KIY70619.1 - 0.042 12.4 1.3 0.053 12.1 1.3 1.1 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) ADK_lid PF05191.14 KIY70619.1 - 0.081 12.9 2.4 0.23 11.5 2.4 1.9 1 1 0 1 1 1 0 Adenylate kinase, active site lid Zn_Tnp_IS1595 PF12760.7 KIY70619.1 - 0.099 12.6 4.1 1.6 8.7 0.6 2.4 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-C2H2_11 PF16622.5 KIY70619.1 - 0.12 12.1 3.9 4.2 7.2 0.1 2.7 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-BED PF02892.15 KIY70619.1 - 0.15 12.1 4.5 5 7.2 1.0 2.7 1 1 1 2 2 2 0 BED zinc finger C1_4 PF07975.12 KIY70619.1 - 0.16 12.2 1.7 0.59 10.4 1.6 2.0 1 1 1 2 2 2 0 TFIIH C1-like domain HypA PF01155.19 KIY70619.1 - 0.19 11.8 0.5 0.3 11.1 0.5 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-HYPF PF07503.12 KIY70619.1 - 0.2 11.5 4.1 3.9 7.3 0.5 2.6 2 0 0 2 2 2 0 HypF finger zf-C2HC_2 PF13913.6 KIY70619.1 - 0.22 11.5 9.2 0.3 11.0 1.3 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Zn_ribbon_SprT PF17283.2 KIY70619.1 - 0.25 11.3 7.2 1.5 8.8 0.5 2.6 2 0 0 2 2 2 0 SprT-like zinc ribbon domain zinc_ribbon_4 PF13717.6 KIY70619.1 - 0.33 10.9 2.1 14 5.7 0.2 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf-Di19 PF05605.12 KIY70619.1 - 1.3 9.4 6.6 0.41 11.0 3.6 1.8 2 0 0 2 2 1 0 Drought induced 19 protein (Di19), zinc-binding zf-nanos PF05741.13 KIY70619.1 - 3.3 8.0 7.9 0.29 11.4 0.8 2.7 3 0 0 3 3 2 0 Nanos RNA binding domain zf-H2C2_2 PF13465.6 KIY70619.1 - 6.6 7.3 13.7 3.6 8.2 0.6 2.8 2 1 1 3 3 2 0 Zinc-finger double domain DUF629 PF04780.12 KIY70619.1 - 8.4 4.8 5.6 39 2.6 5.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF629) F-box-like PF12937.7 KIY70620.1 - 3.2e-08 33.3 2.1 1.9e-07 30.9 0.5 2.7 2 1 0 2 2 2 1 F-box-like AbfS_sensor PF18225.1 KIY70620.1 - 0.26 11.2 0.5 3.6 7.6 0.1 2.5 2 0 0 2 2 2 0 Sensor histidine kinase (AbfS) sensor domain Metallophos PF00149.28 KIY70621.1 - 2.9e-36 125.9 0.5 3.7e-36 125.6 0.5 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KIY70621.1 - 0.072 13.6 0.8 0.16 12.5 0.8 1.6 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain F-box-like PF12937.7 KIY70622.1 - 7.7e-07 28.9 0.4 1.8e-06 27.7 0.4 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY70622.1 - 0.035 14.0 0.0 0.14 12.1 0.0 2.0 2 1 0 2 2 2 0 F-box domain CRAL_TRIO PF00650.20 KIY70623.1 - 3.4e-13 49.6 0.0 5e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain Voltage_CLC PF00654.20 KIY70625.1 - 8.3e-88 295.0 34.5 8.3e-88 295.0 34.5 1.5 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 KIY70625.1 - 4e-11 43.2 0.8 5.6e-05 23.5 0.0 2.7 2 0 0 2 2 2 2 CBS domain F-box-like PF12937.7 KIY70626.1 - 5.1e-10 39.1 0.0 1.7e-09 37.4 0.0 2.0 1 0 0 1 1 1 1 F-box-like Hs1pro-1_N PF07231.12 KIY70626.1 - 0.028 14.2 0.8 0.12 12.1 0.4 2.1 1 1 0 2 2 2 0 Hs1pro-1 N-terminus CLIP PF12032.8 KIY70626.1 - 0.11 12.9 0.0 0.26 11.6 0.0 1.6 1 0 0 1 1 1 0 Regulatory CLIP domain of proteinases F-box PF00646.33 KIY70627.1 - 0.01 15.7 0.5 0.06 13.2 0.4 2.4 2 0 0 2 2 2 0 F-box domain DUF4745 PF15923.5 KIY70627.1 - 0.11 12.5 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4745) zf-CCCH PF00642.24 KIY70628.1 - 2.1e-09 37.0 2.7 4.8e-09 35.9 2.7 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.6 KIY70628.1 - 1.8e-06 27.7 6.7 3.5e-06 26.8 6.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf_CCCH_4 PF18345.1 KIY70628.1 - 1.5e-05 24.9 4.4 3e-05 23.9 4.4 1.6 1 0 0 1 1 1 1 Zinc finger domain zf-RING_5 PF14634.6 KIY70628.1 - 1.8e-05 24.6 9.8 3e-05 23.9 9.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KIY70628.1 - 3.7e-05 23.7 7.5 7.4e-05 22.7 7.5 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_10 PF16685.5 KIY70628.1 - 7.2e-05 22.8 2.3 7.2e-05 22.8 2.3 1.6 2 0 0 2 2 1 1 zinc RING finger of MSL2 zf-C3HC4_2 PF13923.6 KIY70628.1 - 0.00015 21.5 9.5 0.00029 20.6 9.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIY70628.1 - 0.00026 20.8 10.0 0.0005 19.9 10.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIY70628.1 - 0.0006 20.1 8.5 0.0012 19.2 8.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 KIY70628.1 - 0.0008 19.5 6.9 0.0019 18.3 6.9 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-CCCH_4 PF18044.1 KIY70628.1 - 0.0013 18.4 2.9 0.003 17.3 2.9 1.7 1 0 0 1 1 1 1 CCCH-type zinc finger Prok-RING_4 PF14447.6 KIY70628.1 - 0.092 12.6 7.4 0.17 11.8 7.4 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-Nse PF11789.8 KIY70628.1 - 0.12 12.2 3.1 0.22 11.4 3.1 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C2H2_jaz PF12171.8 KIY70628.1 - 3.3 8.1 7.0 12 6.4 0.1 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding bZIP_2 PF07716.15 KIY70629.1 - 7.3e-11 42.0 11.3 7.3e-11 42.0 11.3 2.2 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 KIY70629.1 - 0.0013 18.8 10.9 0.0013 18.8 10.9 2.1 2 1 0 2 2 2 1 bZIP transcription factor Shugoshin_N PF07558.11 KIY70629.1 - 0.0048 16.7 0.1 0.0088 15.9 0.1 1.5 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region HDV_ag PF01517.18 KIY70629.1 - 0.017 14.9 10.6 0.016 15.0 7.1 2.0 2 0 0 2 2 2 0 Hepatitis delta virus delta antigen bZIP_Maf PF03131.17 KIY70629.1 - 0.024 15.1 3.4 0.061 13.8 3.4 1.6 1 0 0 1 1 1 0 bZIP Maf transcription factor TSC22 PF01166.18 KIY70629.1 - 0.057 13.7 0.4 0.11 12.8 0.4 1.4 1 0 0 1 1 1 0 TSC-22/dip/bun family DUF4778 PF16008.5 KIY70629.1 - 0.068 13.2 0.8 0.1 12.7 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) WD40_alt PF14077.6 KIY70629.1 - 0.15 12.0 1.6 0.27 11.1 1.6 1.3 1 0 0 1 1 1 0 Alternative WD40 repeat motif Metallophos PF00149.28 KIY70630.1 - 4.5e-35 122.0 0.1 5.7e-35 121.7 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KIY70630.1 - 0.033 14.4 0.0 0.048 13.8 0.0 1.2 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain BTAD PF03704.17 KIY70631.1 - 0.0097 16.3 3.1 0.0097 16.3 3.1 2.3 1 1 1 2 2 2 1 Bacterial transcriptional activator domain DivIC PF04977.15 KIY70631.1 - 0.062 13.1 13.2 3.4 7.5 0.6 3.7 2 1 1 3 3 3 0 Septum formation initiator ZapB PF06005.12 KIY70631.1 - 0.48 10.9 21.4 0.13 12.7 0.5 3.9 2 1 2 4 4 4 0 Cell division protein ZapB GIT_CC PF16559.5 KIY70631.1 - 0.91 9.4 3.5 29 4.6 0.0 3.2 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor FlaC_arch PF05377.11 KIY70631.1 - 2.6 8.5 6.4 23 5.5 0.1 3.8 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) YabA PF06156.13 KIY70631.1 - 3.1 8.5 9.3 34 5.2 0.4 3.1 1 1 2 3 3 3 0 Initiation control protein YabA TMF_DNA_bd PF12329.8 KIY70631.1 - 4.3 7.4 17.1 3 7.9 1.7 3.7 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding HALZ PF02183.18 KIY70631.1 - 4.4 7.6 6.9 13 6.1 0.8 3.5 3 0 0 3 3 3 0 Homeobox associated leucine zipper LysM PF01476.20 KIY70632.1 - 5.6e-06 26.3 0.0 1.9e-05 24.6 0.0 1.8 2 0 0 2 2 2 1 LysM domain SUZ PF12752.7 KIY70633.1 - 0.055 14.2 1.2 8.2 7.3 0.4 2.5 2 0 0 2 2 2 0 SUZ domain ATP-synt_C PF00137.21 KIY70634.1 - 4.8e-26 90.9 25.2 1.7e-15 57.1 11.7 2.4 2 0 0 2 2 2 2 ATP synthase subunit C G0-G1_switch_2 PF15103.6 KIY70634.1 - 0.055 13.9 0.5 0.94 9.9 0.1 2.2 2 0 0 2 2 2 0 G0/G1 switch protein 2 MerR-DNA-bind PF09278.11 KIY70635.1 - 0.051 14.1 0.7 8.8 7.0 0.0 3.7 4 0 0 4 4 4 0 MerR, DNA binding SET PF00856.28 KIY70636.1 - 9.3e-17 61.9 0.0 1.6e-16 61.2 0.0 1.4 1 0 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.11 KIY70636.1 - 1.8e-09 38.3 0.0 3.7e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding CUE PF02845.16 KIY70637.1 - 7.3e-10 38.4 0.0 2e-09 36.9 0.1 1.7 2 0 0 2 2 2 1 CUE domain F-box-like PF12937.7 KIY70641.1 - 1.1e-07 31.6 0.2 5.2e-07 29.4 0.2 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIY70641.1 - 3.5 7.6 6.4 12 6.0 3.3 3.4 2 1 0 2 2 2 0 F-box domain GLTP PF08718.11 KIY70642.1 - 1.9e-46 158.0 0.0 2.4e-46 157.7 0.0 1.1 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) GAF_2 PF13185.6 KIY70643.1 - 0.00012 22.4 0.0 0.00021 21.6 0.0 1.3 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 KIY70643.1 - 0.0039 17.8 0.0 0.0055 17.3 0.0 1.2 1 0 0 1 1 1 1 GAF domain DUF1577 PF07614.11 KIY70643.1 - 0.27 10.3 0.0 0.37 9.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1577) tRNA-synt_1e PF01406.19 KIY70644.1 - 8.6e-126 419.3 0.1 8.6e-126 419.3 0.1 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 KIY70644.1 - 2.6e-08 33.1 0.6 0.00016 20.5 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KIY70644.1 - 2.2e-05 23.0 0.0 0.0085 14.4 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) DALR_2 PF09190.11 KIY70644.1 - 0.001 19.5 0.0 0.001 19.5 0.0 2.8 3 0 0 3 3 3 1 DALR domain tRNA-synt_1c PF00749.21 KIY70644.1 - 0.056 12.3 0.6 0.12 11.2 0.0 1.9 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain Gti1_Pac2 PF09729.9 KIY70645.1 - 7.9e-29 101.0 0.1 1.2e-24 87.4 0.1 2.1 1 1 1 2 2 2 2 Gti1/Pac2 family Gti1_Pac2 PF09729.9 KIY70646.1 - 4.2e-21 75.8 0.2 4.2e-21 75.8 0.2 3.3 2 2 1 3 3 3 2 Gti1/Pac2 family TFIIA PF03153.13 KIY70647.1 - 2.8e-53 182.4 9.8 1.4e-36 127.4 3.5 2.1 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit Nucleoporin_FG PF13634.6 KIY70648.1 - 0.024 15.5 7.3 0.036 14.9 7.3 1.2 1 0 0 1 1 1 0 Nucleoporin FG repeat region YdfA_immunity PF12127.8 KIY70648.1 - 5.3 6.0 7.0 6.9 5.6 7.0 1.1 1 0 0 1 1 1 0 SigmaW regulon antibacterial DUF747 PF05346.11 KIY70649.1 - 2.6e-107 359.0 2.5 3.3e-107 358.7 2.5 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family DUF1463 PF07316.11 KIY70649.1 - 0.14 12.0 0.2 0.24 11.3 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1463) DRIM PF07539.12 KIY70650.1 - 7.7e-154 513.4 1.7 7.7e-154 513.4 1.7 4.9 6 1 0 6 6 6 1 Down-regulated in metastasis MMS19_N PF14500.6 KIY70650.1 - 0.0016 18.0 1.7 0.046 13.3 1.4 3.2 2 0 0 2 2 2 1 Dos2-interacting transcription regulator of RNA-Pol-II PLN_propep PF16485.5 KIY70650.1 - 0.0057 16.3 0.1 0.024 14.3 0.1 2.1 1 0 0 1 1 1 1 Protealysin propeptide RRP36 PF06102.12 KIY70650.1 - 0.012 15.6 2.6 0.024 14.6 2.1 1.7 2 0 0 2 2 2 0 rRNA biogenesis protein RRP36 FAD_binding_1 PF00667.20 KIY70650.1 - 0.098 12.2 0.1 0.27 10.8 0.1 1.7 1 0 0 1 1 1 0 FAD binding domain Condensin2nSMC PF12422.8 KIY70650.1 - 0.42 10.8 9.5 0.49 10.6 0.2 4.9 6 0 0 6 6 6 0 Condensin II non structural maintenance of chromosomes subunit Sec7_N PF12783.7 KIY70650.1 - 0.44 10.4 7.7 4.7 7.1 0.3 4.5 2 1 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF4632 PF15451.6 KIY70650.1 - 0.5 10.5 4.0 13 6.0 0.1 3.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4632) F-box-like PF12937.7 KIY70651.1 - 3.4e-06 26.9 2.5 1.3e-05 25.0 2.5 2.1 1 0 0 1 1 1 1 F-box-like Baculo_PEP_C PF04513.12 KIY70651.1 - 0.13 12.3 0.6 0.41 10.7 0.6 1.8 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus F-box-like PF12937.7 KIY70652.1 - 1.2e-06 28.3 3.6 2.8e-06 27.1 0.3 3.1 3 1 0 3 3 3 1 F-box-like DivIC PF04977.15 KIY70652.1 - 0.011 15.5 0.1 0.044 13.6 0.1 1.9 2 0 0 2 2 2 0 Septum formation initiator TMF_TATA_bd PF12325.8 KIY70652.1 - 0.025 14.8 0.0 0.064 13.5 0.0 1.6 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding F-box PF00646.33 KIY70652.1 - 0.36 10.8 2.1 51 3.9 0.2 3.5 3 0 0 3 3 3 0 F-box domain OsmC PF02566.19 KIY70653.1 - 8e-13 48.7 0.0 1.3e-12 48.0 0.0 1.3 1 0 0 1 1 1 1 OsmC-like protein F-box-like PF12937.7 KIY70654.1 - 5.9e-05 22.9 0.6 0.00029 20.7 0.6 2.2 2 1 0 2 2 2 1 F-box-like Muted PF14942.6 KIY70654.1 - 0.039 14.3 0.0 0.044 14.1 0.0 1.2 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein LRR_2 PF07723.13 KIY70655.1 - 0.017 15.8 0.4 1.8 9.4 0.0 3.5 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_4 PF12799.7 KIY70655.1 - 0.032 14.6 3.5 5.4 7.6 0.2 4.7 4 2 1 5 5 5 0 Leucine Rich repeats (2 copies) MMS1_N PF10433.9 KIY70657.1 - 1e-155 519.2 0.0 1.4e-155 518.7 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 KIY70657.1 - 4.3e-89 299.0 0.0 1.2e-88 297.6 0.0 1.8 2 0 0 2 2 2 1 CPSF A subunit region zf-MYND PF01753.18 KIY70658.1 - 4.4e-08 33.1 13.0 8.6e-08 32.1 13.0 1.5 1 0 0 1 1 1 1 MYND finger F-box-like PF12937.7 KIY70661.1 - 0.0045 16.9 0.2 0.0045 16.9 0.2 2.3 2 0 0 2 2 2 1 F-box-like Skp1_POZ PF03931.15 KIY70662.1 - 0.00056 20.0 0.0 0.0061 16.7 0.0 2.1 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain Voldacs PF03517.13 KIY70663.1 - 1.3e-26 93.4 0.9 1.8e-26 93.0 0.9 1.2 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling ABC_membrane PF00664.23 KIY70664.1 - 5.3e-47 160.8 21.3 1.1e-25 90.9 4.4 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KIY70664.1 - 3.7e-42 144.1 0.2 9.4e-27 94.2 0.2 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KIY70664.1 - 2.6e-12 46.6 5.9 0.00093 18.7 0.4 4.2 2 2 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KIY70664.1 - 1.2e-05 25.8 0.6 0.0083 16.5 0.2 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 KIY70664.1 - 3e-05 24.6 0.4 0.0021 18.6 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KIY70664.1 - 4.1e-05 23.2 1.0 0.069 12.7 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.6 KIY70664.1 - 0.00021 21.0 1.9 0.24 11.2 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SSE PF00437.20 KIY70664.1 - 0.00044 19.4 0.4 0.085 11.9 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein DUF87 PF01935.17 KIY70664.1 - 0.00091 19.4 0.5 0.038 14.1 0.1 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_22 PF13401.6 KIY70664.1 - 0.00096 19.4 2.0 1.6 9.0 0.0 3.3 2 1 0 2 2 2 2 AAA domain AAA_21 PF13304.6 KIY70664.1 - 0.0016 18.4 6.0 1.2 8.9 0.1 4.4 4 1 0 5 5 4 1 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 KIY70664.1 - 0.0032 17.5 0.3 0.81 9.8 0.1 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase DEAD PF00270.29 KIY70664.1 - 0.0051 16.6 1.3 3.9 7.2 1.0 3.3 2 1 0 2 2 2 1 DEAD/DEAH box helicase AAA PF00004.29 KIY70664.1 - 0.0055 17.1 0.9 4.5 7.7 0.0 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KIY70664.1 - 0.0092 15.5 0.2 5.2 6.5 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region RsgA_GTPase PF03193.16 KIY70664.1 - 0.0097 15.8 0.5 1.8 8.4 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase ResIII PF04851.15 KIY70664.1 - 0.017 15.1 0.0 5.5 7.0 0.0 3.1 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit Adeno_IVa2 PF02456.15 KIY70664.1 - 0.024 13.5 0.1 0.11 11.2 0.0 1.9 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_5 PF07728.14 KIY70664.1 - 0.046 13.7 1.3 20 5.2 0.1 3.8 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 KIY70664.1 - 0.059 13.1 0.2 1.3 8.7 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KIY70664.1 - 0.082 13.5 0.0 8.9 6.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 KIY70664.1 - 0.089 12.1 1.1 8.6 5.6 0.1 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family Dynamin_N PF00350.23 KIY70664.1 - 0.093 12.8 0.8 9.3 6.3 0.0 2.4 2 0 0 2 2 2 0 Dynamin family Pox_A32 PF04665.12 KIY70664.1 - 0.11 11.9 2.1 9.3 5.6 0.2 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein IstB_IS21 PF01695.17 KIY70664.1 - 0.13 12.0 2.7 6.7 6.4 0.0 3.0 4 0 0 4 4 2 0 IstB-like ATP binding protein AAA_15 PF13175.6 KIY70664.1 - 0.29 10.8 0.0 3.8 7.1 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain cobW PF02492.19 KIY70664.1 - 0.44 10.1 1.7 2.1 7.9 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 KIY70664.1 - 1.1 9.0 8.4 0.93 9.2 0.0 3.3 3 1 0 3 3 2 0 AAA domain Chlorophyllase2 PF12740.7 KIY70665.1 - 0.035 13.0 0.0 0.092 11.6 0.0 1.6 2 0 0 2 2 2 0 Chlorophyllase enzyme YscO PF07321.12 KIY70666.1 - 0.00055 19.9 0.4 0.00055 19.9 0.4 1.9 3 0 0 3 3 1 1 Type III secretion protein YscO TT_ORF2 PF02957.15 KIY70666.1 - 0.024 15.6 3.0 0.024 15.6 3.0 3.1 3 0 0 3 3 3 0 TT viral ORF2 Suppressor_APC PF11414.8 KIY70666.1 - 0.042 13.9 1.3 0.093 12.8 1.3 1.6 1 0 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein GAS PF13851.6 KIY70666.1 - 0.056 12.8 0.2 0.096 12.0 0.2 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding TMF_TATA_bd PF12325.8 KIY70666.1 - 0.063 13.5 0.6 0.12 12.7 0.6 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Takusan PF04822.13 KIY70666.1 - 0.095 12.6 0.2 0.24 11.3 0.2 1.7 1 0 0 1 1 1 0 Takusan PilJ PF13675.6 KIY70666.1 - 0.096 12.7 0.3 0.26 11.3 0.3 1.7 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term DZR PF12773.7 KIY70666.1 - 0.14 12.2 1.5 0.28 11.2 1.5 1.5 1 0 0 1 1 1 0 Double zinc ribbon DUF4201 PF13870.6 KIY70666.1 - 0.14 11.9 1.4 0.24 11.1 1.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) JIP_LZII PF16471.5 KIY70666.1 - 0.18 12.0 0.3 0.18 12.0 0.3 1.7 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II FliJ PF02050.16 KIY70666.1 - 3.8 7.7 8.5 0.079 13.2 1.5 1.7 2 0 0 2 2 1 0 Flagellar FliJ protein ATG16 PF08614.11 KIY70666.1 - 4.1 7.6 10.1 0.15 12.3 0.9 2.6 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) Solute_trans_a PF03619.16 KIY70667.1 - 3.3e-95 318.6 11.0 4e-95 318.3 11.0 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha zf-MYND PF01753.18 KIY70669.1 - 9.6e-08 32.0 10.6 2.1e-07 30.9 10.6 1.6 1 0 0 1 1 1 1 MYND finger HEAT_EZ PF13513.6 KIY70670.1 - 1.7e-24 85.9 13.8 1.4e-14 54.2 0.0 8.2 7 1 1 8 8 8 3 HEAT-like repeat HEAT PF02985.22 KIY70670.1 - 6.1e-19 66.5 10.9 0.00026 21.0 0.0 8.3 7 0 0 7 7 7 5 HEAT repeat HEAT_2 PF13646.6 KIY70670.1 - 1.7e-14 54.0 0.3 1.1e-05 25.7 0.0 6.7 5 3 3 8 8 8 3 HEAT repeats Vac14_Fab1_bd PF12755.7 KIY70670.1 - 4.2e-08 33.7 0.0 0.033 14.8 0.1 4.1 4 1 1 5 5 3 3 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KIY70670.1 - 1.4e-06 28.4 0.1 0.4 10.7 0.1 4.4 4 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 DUF3437 PF11919.8 KIY70670.1 - 1.4e-05 24.9 0.1 1.4 8.9 0.0 4.8 4 0 0 4 4 4 1 Domain of unknown function (DUF3437) Tti2 PF10521.9 KIY70670.1 - 0.00033 20.3 0.3 0.38 10.2 0.0 3.3 2 1 1 3 3 3 2 Tti2 family TAF1_subA PF14929.6 KIY70670.1 - 0.00037 20.0 0.1 0.00062 19.3 0.1 1.3 1 0 0 1 1 1 1 TAF RNA Polymerase I subunit A Adaptin_N PF01602.20 KIY70670.1 - 0.00058 18.5 0.6 0.021 13.4 0.0 3.3 4 0 0 4 4 4 1 Adaptin N terminal region IBN_N PF03810.19 KIY70670.1 - 0.0046 16.8 0.0 0.017 15.0 0.0 2.1 1 0 0 1 1 1 1 Importin-beta N-terminal domain RTP1_C1 PF10363.9 KIY70670.1 - 0.015 15.4 0.0 0.11 12.6 0.0 2.6 3 0 0 3 3 1 0 Required for nuclear transport of RNA pol II C-terminus 1 Cohesin_HEAT PF12765.7 KIY70670.1 - 0.022 15.1 0.7 3.3 8.1 0.1 3.5 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion CbeA_antitoxin PF06154.11 KIY70670.1 - 0.051 14.2 0.0 0.14 12.7 0.0 1.7 1 0 0 1 1 1 0 CbeA_antitoxin, type IV, cytoskeleton bundling-enhancing factor A MMS19_C PF12460.8 KIY70670.1 - 0.058 12.5 0.1 0.25 10.4 0.0 2.1 3 0 0 3 3 3 0 RNAPII transcription regulator C-terminal Arm PF00514.23 KIY70670.1 - 0.24 11.5 7.5 18 5.5 0.0 5.5 6 0 0 6 6 5 0 Armadillo/beta-catenin-like repeat XPC-binding PF09280.11 KIY70670.1 - 4.2 7.2 7.3 3.7 7.4 0.1 3.9 4 0 0 4 4 3 0 XPC-binding domain F-box-like PF12937.7 KIY70672.1 - 0.00097 19.0 0.0 0.0026 17.6 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY70672.1 - 0.0034 17.2 0.0 0.011 15.6 0.0 1.9 1 0 0 1 1 1 1 F-box domain EnY2 PF10163.9 KIY70673.1 - 5.7e-11 42.6 0.2 7e-11 42.4 0.2 1.2 1 0 0 1 1 1 1 Transcription factor e(y)2 DEAD PF00270.29 KIY70674.1 - 3e-43 147.6 0.1 4.5e-43 147.0 0.1 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIY70674.1 - 1.2e-28 99.7 0.6 3.3e-27 95.0 0.4 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.6 KIY70674.1 - 0.011 15.1 0.1 0.022 14.1 0.1 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit GST_N PF02798.20 KIY70675.1 - 4.7e-20 71.7 0.0 8.6e-20 70.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KIY70675.1 - 4.8e-17 62.1 0.0 8e-17 61.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KIY70675.1 - 3.2e-10 40.2 0.0 1.2e-09 38.3 0.0 1.9 1 1 1 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KIY70675.1 - 5.4e-08 32.9 0.0 7.8e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KIY70675.1 - 0.00033 20.6 0.0 0.00055 19.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KIY70675.1 - 0.0066 16.6 0.0 0.012 15.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Lipl32 PF12103.8 KIY70678.1 - 0.0054 16.4 0.1 0.0066 16.1 0.1 1.2 1 0 0 1 1 1 1 Surface lipoprotein of Spirochaetales order zf-C3HC4_3 PF13920.6 KIY70679.1 - 1e-13 50.9 6.4 1e-13 50.9 6.4 2.8 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KIY70679.1 - 4.8e-10 39.1 6.0 4.8e-10 39.1 6.0 3.0 3 1 1 4 4 3 1 Prokaryotic RING finger family 4 FYVE PF01363.21 KIY70679.1 - 1.2e-07 31.7 6.1 1.2e-07 31.7 6.1 2.7 2 1 0 2 2 1 1 FYVE zinc finger zf-RING_2 PF13639.6 KIY70679.1 - 1.5e-06 28.4 5.7 1.5e-06 28.4 5.7 2.7 2 1 0 2 2 2 1 Ring finger domain FYVE_2 PF02318.16 KIY70679.1 - 3.7e-05 23.9 4.1 3.7e-05 23.9 4.1 3.3 3 1 0 3 3 3 1 FYVE-type zinc finger zf-C3HC4 PF00097.25 KIY70679.1 - 8.7e-05 22.3 6.7 8.7e-05 22.3 6.7 3.3 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KIY70679.1 - 0.0026 17.6 6.4 0.0026 17.6 6.4 3.3 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-P11 PF03854.14 KIY70679.1 - 0.0072 16.0 4.0 0.0072 16.0 4.0 3.0 3 0 0 3 3 3 1 P-11 zinc finger zf-UDP PF14569.6 KIY70679.1 - 0.35 11.0 13.0 0.97 9.6 2.5 2.7 2 0 0 2 2 2 0 Zinc-binding RING-finger zf-RING_5 PF14634.6 KIY70679.1 - 4.3 7.4 21.5 0.059 13.3 4.8 2.8 2 1 0 2 2 2 0 zinc-RING finger domain Pro-rich PF15240.6 KIY70679.1 - 8 6.7 50.1 2.5 8.4 1.7 2.6 3 0 0 3 3 3 0 Proline-rich Histone PF00125.24 KIY70680.1 - 1.1e-50 171.4 3.0 1.2e-50 171.3 3.0 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KIY70680.1 - 2.6e-05 24.5 0.1 4e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KIY70680.1 - 6.2e-05 23.1 0.6 9.7e-05 22.4 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 KIY70680.1 - 0.0011 19.2 1.2 0.0014 18.9 0.1 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PAF PF15715.5 KIY70680.1 - 0.0028 18.2 1.9 0.0036 17.9 1.9 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain Bromo_TP PF07524.13 KIY70680.1 - 0.086 12.9 0.1 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 Bromodomain associated TFIID-31kDa PF02291.15 KIY70680.1 - 0.11 12.6 0.3 0.17 12.0 0.1 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Ank_2 PF12796.7 KIY70683.1 - 7.1e-07 29.7 0.0 0.025 15.2 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KIY70683.1 - 1.7e-05 24.9 0.0 1.2 9.9 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 KIY70683.1 - 0.00015 22.1 0.7 0.43 11.1 0.0 3.8 3 1 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 KIY70683.1 - 0.00041 20.6 0.3 0.013 15.8 0.1 2.8 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 KIY70683.1 - 0.0028 18.2 0.1 4 8.1 0.0 3.6 3 2 1 5 5 5 2 Ankyrin repeats (many copies) Abhydrolase_1 PF00561.20 KIY70684.1 - 2.4e-15 56.9 0.0 4.7e-15 55.9 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIY70684.1 - 1.5e-08 35.5 0.3 2e-08 35.2 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIY70684.1 - 0.00014 21.2 0.0 0.0019 17.5 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DLH PF01738.18 KIY70684.1 - 0.078 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family Peptidase_S10 PF00450.22 KIY70685.1 - 8.1e-105 351.6 0.0 1e-104 351.3 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase F-box PF00646.33 KIY70686.1 - 3.4e-05 23.6 0.0 7.3e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KIY70686.1 - 0.026 14.4 0.0 0.069 13.1 0.0 1.7 1 0 0 1 1 1 0 F-box-like F-box-like PF12937.7 KIY70688.1 - 0.00027 20.8 1.2 0.00087 19.1 1.2 2.0 1 0 0 1 1 1 1 F-box-like TPT PF03151.16 KIY70689.1 - 4.1e-22 78.9 18.3 5.5e-22 78.5 18.3 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family TMEM238 PF15125.6 KIY70689.1 - 0.15 12.2 7.6 0.67 10.2 7.6 2.2 1 0 0 1 1 1 0 TMEM238 protein family EamA PF00892.20 KIY70689.1 - 0.52 10.5 36.7 0.093 12.9 12.0 2.2 2 0 0 2 2 2 0 EamA-like transporter family MAPEG PF01124.18 KIY70690.1 - 2.9e-14 53.1 0.1 3.4e-14 52.9 0.1 1.0 1 0 0 1 1 1 1 MAPEG family EXS PF03124.14 KIY70691.1 - 3e-61 207.6 15.4 3.4e-61 207.4 15.4 1.0 1 0 0 1 1 1 1 EXS family Abhydrolase_6 PF12697.7 KIY70692.1 - 0.0086 16.7 0.1 0.039 14.6 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 KIY70692.1 - 0.011 15.5 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIY70692.1 - 0.055 12.7 0.0 0.088 12.1 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 KIY70692.1 - 0.16 10.9 0.0 0.25 10.2 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme NTF2 PF02136.20 KIY70694.1 - 9.4e-30 103.7 0.0 1.4e-29 103.1 0.0 1.3 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 KIY70694.1 - 2.7e-10 39.9 0.1 4.6e-10 39.2 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KIY70694.1 - 0.049 13.5 0.1 0.093 12.6 0.1 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif RRM_3 PF08777.11 KIY70694.1 - 0.066 13.3 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 RNA binding motif PQ-loop PF04193.14 KIY70695.1 - 4.2e-30 103.3 6.7 4.1e-16 58.5 1.0 2.6 2 0 0 2 2 2 2 PQ loop repeat ER_lumen_recept PF00810.18 KIY70695.1 - 0.061 14.1 2.4 0.28 12.0 0.3 2.4 2 1 0 2 2 2 0 ER lumen protein retaining receptor Terpene_synth_C PF03936.16 KIY70696.1 - 3.3e-06 26.6 0.0 7.6e-06 25.5 0.0 1.5 2 0 0 2 2 2 1 Terpene synthase family, metal binding domain TRI5 PF06330.11 KIY70696.1 - 0.018 13.9 0.1 0.033 13.1 0.0 1.5 2 0 0 2 2 2 0 Trichodiene synthase (TRI5) MFS_1 PF07690.16 KIY70697.1 - 7.8e-25 87.5 25.2 4e-20 72.0 6.2 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIY70697.1 - 9.7e-05 21.4 11.9 9.7e-05 21.4 11.9 1.7 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 KIY70697.1 - 3 6.6 19.6 0.25 10.2 0.4 3.3 2 2 1 3 3 3 0 MFS_1 like family Glyco_hydro_28 PF00295.17 KIY70699.1 - 5.5e-37 127.6 7.9 1e-36 126.6 7.9 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.6 KIY70699.1 - 0.055 13.3 15.1 0.065 13.1 13.0 2.2 1 1 1 2 2 2 0 Right handed beta helix region Vps16_C PF04840.12 KIY70700.1 - 6.3e-83 278.5 0.1 8.6e-83 278.0 0.1 1.1 1 0 0 1 1 1 1 Vps16, C-terminal region Vps16_N PF04841.13 KIY70700.1 - 1.8e-81 274.0 0.0 2.3e-81 273.7 0.0 1.1 1 0 0 1 1 1 1 Vps16, N-terminal region Arrestin_N PF00339.29 KIY70701.1 - 0.0032 17.6 0.0 0.11 12.5 0.0 2.8 3 0 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain RmlD_sub_bind PF04321.17 KIY70702.1 - 3.3e-55 187.2 0.0 3.9e-55 187.0 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 KIY70702.1 - 3.8e-23 82.2 0.0 4.9e-23 81.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KIY70702.1 - 6.1e-08 32.4 0.0 1e-07 31.7 0.0 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KIY70702.1 - 1.4e-07 31.0 0.1 5e-06 25.9 0.0 2.7 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 KIY70702.1 - 1.3e-05 24.6 0.0 0.00021 20.5 0.0 2.5 2 1 0 2 2 2 1 Male sterility protein EXS PF03124.14 KIY70704.1 - 1e-64 219.0 9.4 1.2e-64 218.8 9.4 1.0 1 0 0 1 1 1 1 EXS family Glyco_transf_8C PF08437.10 KIY70704.1 - 0.11 12.6 2.6 0.9 9.7 0.6 2.4 2 0 0 2 2 2 0 Glycosyl transferase family 8 C-terminal SPX PF03105.19 KIY70705.1 - 1.7e-47 163.2 16.1 1.7e-27 97.4 4.4 2.1 1 1 1 2 2 2 2 SPX domain EXS PF03124.14 KIY70705.1 - 0.00038 19.9 1.0 0.00062 19.2 1.0 1.3 1 0 0 1 1 1 1 EXS family Sulfotransfer_3 PF13469.6 KIY70705.1 - 0.0022 18.4 0.2 0.0054 17.1 0.0 1.7 2 0 0 2 2 2 1 Sulfotransferase family FAM153 PF15722.5 KIY70705.1 - 0.0081 16.5 0.1 0.0081 16.5 0.1 1.9 2 0 0 2 2 2 1 FAM153 family P4Ha_N PF08336.11 KIY70705.1 - 0.19 11.7 3.1 1.3 9.0 1.6 2.3 2 1 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Euplotes_phero PF05842.11 KIY70706.1 - 1.5 9.4 6.9 8.2 7.0 3.3 2.3 1 1 1 2 2 2 0 Euplotes octocarinatus mating pheromone protein Fasciclin PF02469.22 KIY70707.1 - 3.2e-12 46.8 0.0 4.3e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 Fasciclin domain F-box-like PF12937.7 KIY70708.1 - 0.015 15.2 0.3 0.057 13.3 0.1 2.1 2 0 0 2 2 2 0 F-box-like DMAP_binding PF06464.11 KIY70708.1 - 0.021 15.7 0.0 0.085 13.7 0.0 1.8 2 0 0 2 2 2 0 DMAP1-binding Domain F-box PF00646.33 KIY70708.1 - 0.033 14.1 0.2 0.071 13.0 0.2 1.5 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 KIY70709.1 - 0.01 15.7 0.0 0.024 14.5 0.0 1.6 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 KIY70709.1 - 0.015 15.2 0.0 0.037 13.9 0.0 1.7 1 0 0 1 1 1 0 F-box domain F-box PF00646.33 KIY70710.1 - 0.0016 18.2 0.0 0.0081 16.0 0.0 2.2 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KIY70710.1 - 0.031 14.2 0.0 0.24 11.3 0.0 2.3 2 0 0 2 2 2 0 F-box-like Peptidase_S8 PF00082.22 KIY70711.1 - 3.6e-34 118.4 7.8 5.9e-34 117.7 7.8 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KIY70711.1 - 6.2e-15 55.6 0.0 1.1e-14 54.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 DUF2076 PF09849.9 KIY70713.1 - 0.011 15.9 5.4 0.012 15.7 5.4 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Glyco_hydro_11 PF00457.17 KIY70714.1 - 1.4e-73 246.3 15.6 1.7e-73 246.1 15.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 F-box-like PF12937.7 KIY70715.1 - 0.00017 21.4 2.4 0.00048 20.0 2.4 1.7 1 1 0 1 1 1 1 F-box-like F-box-like PF12937.7 KIY70716.1 - 2.4e-06 27.4 3.2 5.5e-06 26.2 3.2 1.7 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KIY70717.1 - 1.2e-09 37.8 1.7 3.9e-09 36.2 1.7 1.9 1 0 0 1 1 1 1 F-box-like PelD_GGDEF PF16963.5 KIY70717.1 - 0.13 12.1 0.0 0.32 10.8 0.0 1.7 1 0 0 1 1 1 0 PelD GGDEF domain F-box PF00646.33 KIY70717.1 - 6.9 6.7 7.8 9.6 6.2 3.7 3.2 3 1 0 3 3 3 0 F-box domain adh_short_C2 PF13561.6 KIY70718.1 - 2e-46 158.4 0.5 2.4e-46 158.2 0.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIY70718.1 - 1.1e-38 132.7 0.4 1.4e-38 132.3 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIY70718.1 - 9.8e-15 54.9 0.3 1.3e-14 54.5 0.3 1.2 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 KIY70718.1 - 4.4e-06 25.9 0.1 5.4e-06 25.6 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KIY70718.1 - 5.7e-06 26.0 0.0 9.1e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KIY70718.1 - 0.00013 21.5 0.0 0.00038 20.0 0.0 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase DUF1776 PF08643.10 KIY70718.1 - 0.001 18.5 0.0 0.0015 18.0 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.15 KIY70718.1 - 0.027 13.6 0.1 0.038 13.1 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ELFV_dehydrog PF00208.21 KIY70718.1 - 0.062 13.0 0.0 0.085 12.6 0.0 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Mem_trans PF03547.18 KIY70719.1 - 5.2e-17 61.3 5.9 3.1e-16 58.8 5.9 1.8 1 1 0 1 1 1 1 Membrane transport protein ADH_zinc_N PF00107.26 KIY70720.1 - 9.2e-30 103.3 0.9 1.5e-29 102.6 0.9 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIY70720.1 - 1.1e-26 92.9 2.0 1.7e-26 92.2 2.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KIY70720.1 - 3.5e-07 31.4 0.2 6.3e-07 30.5 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Fer4_4 PF12800.7 KIY70720.1 - 4.4 8.0 6.6 3.6 8.3 2.2 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain ApbA PF02558.16 KIY70722.1 - 8.4e-17 61.2 0.0 1.3e-16 60.6 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 KIY70722.1 - 1.2e-15 57.8 0.0 1.5e-13 51.1 0.0 2.3 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ThiF PF00899.21 KIY70722.1 - 0.1 11.9 0.2 0.18 11.1 0.2 1.3 1 0 0 1 1 1 0 ThiF family ApbA PF02558.16 KIY70723.1 - 1.1e-16 60.8 0.0 1.7e-16 60.2 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 KIY70723.1 - 6.8e-14 52.2 0.1 3e-12 46.8 0.0 2.6 3 0 0 3 3 3 1 Ketopantoate reductase PanE/ApbA C terminal ThiF PF00899.21 KIY70723.1 - 0.00075 18.9 0.1 0.0023 17.4 0.0 1.7 2 0 0 2 2 2 1 ThiF family Shikimate_DH PF01488.20 KIY70723.1 - 0.021 14.9 0.1 0.047 13.8 0.1 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase UcrQ PF02939.16 KIY70724.1 - 1.9e-24 85.3 2.2 2.4e-24 85.0 2.2 1.1 1 0 0 1 1 1 1 UcrQ family OTT_1508_deam PF14441.6 KIY70725.1 - 1e-06 28.6 0.1 2.1e-06 27.6 0.1 1.6 1 0 0 1 1 1 1 OTT_1508-like deaminase Glyco_hydro_17 PF00332.18 KIY70726.1 - 4.3e-09 36.4 1.3 1.5e-06 28.0 0.1 2.2 2 1 0 2 2 2 2 Glycosyl hydrolases family 17 AF-4 PF05110.13 KIY70726.1 - 0.29 9.2 6.4 0.4 8.7 6.4 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein SR-25 PF10500.9 KIY70726.1 - 9.1 5.8 14.1 15 5.1 14.1 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein F-box-like PF12937.7 KIY70727.1 - 2.8e-08 33.5 0.3 1.2e-07 31.5 0.3 2.2 1 0 0 1 1 1 1 F-box-like GMC_oxred_N PF00732.19 KIY70729.1 - 2.2e-64 217.7 0.0 2.8e-64 217.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIY70729.1 - 4.6e-36 124.5 0.0 7.9e-36 123.7 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KIY70729.1 - 5.7e-07 29.0 0.1 0.003 16.7 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KIY70729.1 - 1.1e-06 28.1 0.1 0.0053 16.0 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KIY70729.1 - 1.1e-05 24.8 0.0 0.035 13.3 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KIY70729.1 - 0.00015 21.0 0.0 0.00022 20.4 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 KIY70729.1 - 0.0024 17.2 0.0 0.0067 15.7 0.1 1.6 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 KIY70729.1 - 0.0052 16.4 0.5 0.018 14.6 0.5 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KIY70729.1 - 0.014 15.6 1.4 0.026 14.7 0.1 2.1 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KIY70729.1 - 0.021 13.5 0.1 0.067 11.9 0.1 1.7 2 0 0 2 2 2 0 HI0933-like protein BTB PF00651.31 KIY70730.1 - 1.5e-09 38.1 0.6 2.4e-09 37.4 0.6 1.3 1 0 0 1 1 1 1 BTB/POZ domain DUF2605 PF10792.9 KIY70730.1 - 0.13 12.2 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2605) OTT_1508_deam PF14441.6 KIY70731.1 - 1.6e-11 44.0 0.9 3e-11 43.2 0.9 1.4 1 0 0 1 1 1 1 OTT_1508-like deaminase WD40 PF00400.32 KIY70735.1 - 4.9e-38 128.5 26.6 5.8e-08 33.3 0.0 12.1 12 0 0 12 12 12 7 WD domain, G-beta repeat Utp12 PF04003.12 KIY70735.1 - 4.8e-26 91.2 0.0 7.5e-26 90.5 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 KIY70735.1 - 5.9e-21 74.6 0.0 0.077 13.3 0.0 9.0 2 2 5 9 9 9 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIY70735.1 - 2.4e-07 30.0 4.9 1.1 8.1 0.1 5.9 4 2 1 6 6 6 3 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KIY70735.1 - 0.00014 21.7 0.0 9 6.4 0.0 4.8 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat ELYS-bb PF16687.5 KIY70735.1 - 0.00033 19.4 0.0 0.00069 18.3 0.0 1.5 1 0 0 1 1 1 1 beta-propeller of ELYS nucleoporin Cytochrom_D1 PF02239.16 KIY70735.1 - 0.0036 15.9 0.5 6.2 5.2 0.0 3.5 3 0 0 3 3 3 2 Cytochrome D1 heme domain WD40_like PF17005.5 KIY70735.1 - 0.0043 16.4 0.1 1.1 8.5 0.0 4.1 5 0 0 5 5 5 1 WD40-like domain RAB3GAP2_N PF14655.6 KIY70735.1 - 0.0047 16.2 0.1 0.067 12.4 0.0 2.9 4 0 0 4 4 4 1 Rab3 GTPase-activating protein regulatory subunit N-terminus Nbas_N PF15492.6 KIY70735.1 - 0.021 14.2 0.9 12 5.1 0.0 4.4 3 2 1 5 5 5 0 Neuroblastoma-amplified sequence, N terminal DUF1513 PF07433.11 KIY70735.1 - 0.031 13.4 0.0 2.8 7.0 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1513) PQQ_3 PF13570.6 KIY70735.1 - 8.4 7.0 10.8 1.3 9.6 0.2 4.7 5 1 0 5 5 5 0 PQQ-like domain Peptidase_S10 PF00450.22 KIY70737.1 - 7.9e-86 289.1 0.3 9.5e-86 288.8 0.3 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase DUF1363 PF07101.11 KIY70738.1 - 0.019 15.3 0.1 0.024 14.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1363) DUF4748 PF15932.5 KIY70741.1 - 0.0098 15.6 0.2 0.014 15.1 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4748) TMEM89 PF15098.6 KIY70741.1 - 0.17 12.0 0.0 0.2 11.8 0.0 1.1 1 0 0 1 1 1 0 TMEM89 protein family Rad51 PF08423.11 KIY70743.1 - 2.3e-08 33.6 0.0 3.3e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Rad51 CbiA PF01656.23 KIY70743.1 - 0.0027 17.8 0.0 0.0044 17.1 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ATPase PF06745.13 KIY70743.1 - 0.0048 16.3 0.0 0.007 15.7 0.0 1.2 1 0 0 1 1 1 1 KaiC PAXNEB PF05625.11 KIY70743.1 - 0.021 14.0 0.7 0.045 12.9 0.2 1.8 1 1 1 2 2 2 0 PAXNEB protein RecA PF00154.21 KIY70743.1 - 0.031 13.8 0.0 0.054 12.9 0.0 1.3 1 0 0 1 1 1 0 recA bacterial DNA recombination protein WD40 PF00400.32 KIY70744.1 - 6.8e-11 42.5 13.6 0.44 11.5 0.2 7.3 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY70744.1 - 0.012 15.9 0.1 0.28 11.5 0.0 2.9 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 KIY70744.1 - 0.015 15.8 1.0 0.26 11.8 0.1 3.4 4 0 0 4 4 4 0 PQQ-like domain Muted PF14942.6 KIY70744.1 - 3.8 7.8 9.2 0.044 14.1 1.7 1.5 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein Tyrosinase PF00264.20 KIY70745.1 - 1.8e-50 172.3 2.9 3.6e-50 171.3 2.9 1.5 1 0 0 1 1 1 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 KIY70745.1 - 2.7e-25 89.4 0.0 4.3e-25 88.7 0.0 1.3 1 0 0 1 1 1 1 Tyosinase C-terminal domain DUF4515 PF14988.6 KIY70746.1 - 0.017 15.0 0.0 0.019 14.8 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) Aminotran_1_2 PF00155.21 KIY70749.1 - 1.4e-42 146.2 0.0 1.5e-42 146.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KIY70749.1 - 1.3e-06 28.0 0.1 2e-06 27.4 0.1 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 KIY70749.1 - 3.1e-05 22.7 0.0 4.8e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KIY70749.1 - 0.016 14.2 0.0 0.041 12.8 0.0 1.6 2 0 0 2 2 2 0 Aminotransferase class-V Beta_elim_lyase PF01212.21 KIY70749.1 - 0.088 12.1 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase Aldo_ket_red PF00248.21 KIY70751.1 - 5.7e-79 265.4 0.0 6.4e-79 265.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF5020 PF16412.5 KIY70751.1 - 0.067 13.0 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5020) Aldo_ket_red PF00248.21 KIY70752.1 - 5.2e-71 239.2 0.0 5.9e-71 239.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 KIY70753.1 - 2.1e-74 250.4 0.0 2.4e-74 250.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 KIY70754.1 - 1e-77 261.2 0.0 1.2e-77 261.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Fungal_trans PF04082.18 KIY70755.1 - 4.4e-18 65.3 0.2 9.3e-18 64.2 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY70755.1 - 0.00053 20.0 11.8 0.00095 19.2 11.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CCDC14 PF15254.6 KIY70755.1 - 0.42 9.2 6.9 0.61 8.7 6.9 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 14 TFIIA PF03153.13 KIY70755.1 - 0.63 10.0 14.4 1.1 9.2 14.4 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-MYND PF01753.18 KIY70757.1 - 1.1e-09 38.2 33.0 6.6e-09 35.7 12.3 3.7 4 0 0 4 4 4 2 MYND finger zf-MYND PF01753.18 KIY70758.1 - 3.6e-06 27.0 16.7 3.6e-06 27.0 16.7 3.9 4 0 0 4 4 4 2 MYND finger Coronavirus_5 PF05528.11 KIY70758.1 - 0.062 13.3 3.6 5.3 7.1 0.4 2.6 2 0 0 2 2 2 0 Coronavirus gene 5 protein DUF2752 PF10825.8 KIY70758.1 - 0.22 11.6 4.0 0.66 10.1 0.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2752) DUF1489 PF07370.11 KIY70759.1 - 0.026 14.2 0.0 0.033 13.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1489) Aminotran_5 PF00266.19 KIY70760.1 - 1.6e-26 93.1 0.0 2.3e-26 92.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V B12-binding PF02310.19 KIY70760.1 - 0.093 12.8 1.8 0.11 12.5 0.1 1.9 2 0 0 2 2 2 0 B12 binding domain DUF2067 PF09840.9 KIY70760.1 - 0.12 11.9 0.2 0.23 11.0 0.2 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2067) Aminotran_5 PF00266.19 KIY70761.1 - 1.1e-24 87.1 0.0 1.5e-24 86.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Hairy_orange PF07527.13 KIY70761.1 - 0.2 11.9 1.2 21 5.4 0.0 3.2 3 0 0 3 3 3 0 Hairy Orange LEA_3 PF03242.13 KIY70762.1 - 5.8 7.7 10.4 4 8.2 5.5 3.0 2 0 0 2 2 2 0 Late embryogenesis abundant protein NUDIX PF00293.28 KIY70763.1 - 3e-12 46.7 0.0 4.3e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Prenyltrans PF00432.21 KIY70764.1 - 4.1e-30 103.2 13.9 2.6e-06 27.0 1.8 6.0 5 1 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 KIY70764.1 - 0.00015 21.0 0.0 0.52 9.4 0.0 2.6 3 0 0 3 3 3 2 Squalene-hopene cyclase N-terminal domain zf-primase PF09329.11 KIY70765.1 - 2e-15 56.3 2.9 3.7e-15 55.5 2.9 1.5 1 0 0 1 1 1 1 Primase zinc finger CitX PF03802.14 KIY70765.1 - 0.039 13.7 3.7 2 8.2 0.2 2.3 1 1 0 2 2 2 0 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase VPS11_C PF12451.8 KIY70765.1 - 4.1 7.7 4.9 0.43 10.8 0.3 1.8 2 0 0 2 2 2 0 Vacuolar protein sorting protein 11 C terminal PAT1 PF09770.9 KIY70766.1 - 5.5e-97 326.0 61.0 2.3e-95 320.6 61.0 2.7 1 1 0 1 1 1 1 Topoisomerase II-associated protein PAT1 DUF979 PF06166.12 KIY70766.1 - 0.25 10.5 0.7 0.4 9.8 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF979) NMO PF03060.15 KIY70767.1 - 8.9e-46 156.8 0.2 1.4e-45 156.1 0.2 1.3 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KIY70767.1 - 0.00046 19.3 0.0 0.0039 16.2 0.0 2.1 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KIY70767.1 - 0.017 14.1 3.4 0.027 13.5 3.4 1.2 1 0 0 1 1 1 0 FMN-dependent dehydrogenase RRM_1 PF00076.22 KIY70768.1 - 4.5e-20 71.2 0.0 1.3e-13 50.5 0.0 2.4 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 KIY70768.1 - 0.021 14.9 0.3 0.27 11.4 0.2 2.6 3 0 0 3 3 3 0 Limkain b1 RRM_occluded PF16842.5 KIY70768.1 - 0.16 11.8 0.0 0.58 10.1 0.0 1.8 2 0 0 2 2 2 0 Occluded RNA-recognition motif SAC3_GANP PF03399.16 KIY70771.1 - 6.2e-21 75.0 5.0 3.5e-19 69.3 5.0 2.1 1 1 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 KIY70771.1 - 0.00039 20.4 0.3 0.0011 19.0 0.3 1.8 1 1 0 1 1 1 1 CSN8/PSMD8/EIF3K family Cytochrom_C1 PF02167.15 KIY70772.1 - 2.9e-96 321.4 0.0 3.6e-96 321.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 KIY70772.1 - 0.00088 19.6 0.0 0.0018 18.5 0.0 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 KIY70772.1 - 0.0042 18.2 0.1 0.011 16.9 0.1 2.0 1 1 0 1 1 1 1 Cytochrome c Velvet PF11754.8 KIY70774.1 - 1.2e-25 90.9 0.1 5.4e-13 49.5 0.0 2.0 1 1 1 2 2 2 2 Velvet factor TMEM171 PF15471.6 KIY70775.1 - 2.2 7.2 4.0 3.4 6.5 4.0 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 AAA_33 PF13671.6 KIY70777.1 - 7.3e-17 61.9 0.0 2.4e-09 37.5 0.0 2.9 2 1 1 3 3 3 2 AAA domain KTI12 PF08433.10 KIY70777.1 - 4e-05 23.2 0.0 0.011 15.2 0.0 2.1 1 1 1 2 2 2 2 Chromatin associated protein KTI12 AAA_18 PF13238.6 KIY70777.1 - 0.00034 21.2 0.1 0.022 15.3 0.1 2.2 1 1 1 2 2 2 1 AAA domain tRNA_lig_kinase PF08303.11 KIY70777.1 - 0.00051 20.2 0.0 0.00088 19.4 0.0 1.3 1 0 0 1 1 1 1 tRNA ligase kinase domain AAA_16 PF13191.6 KIY70777.1 - 0.0012 19.2 0.0 0.0027 18.1 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KIY70777.1 - 0.0057 16.4 0.0 0.031 14.0 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 KIY70777.1 - 0.05 13.9 0.0 0.091 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain dNK PF01712.19 KIY70777.1 - 0.077 12.8 0.0 0.8 9.5 0.0 2.2 2 1 0 2 2 2 0 Deoxynucleoside kinase Zeta_toxin PF06414.12 KIY70777.1 - 0.11 11.8 0.0 0.33 10.2 0.0 1.8 2 1 0 2 2 2 0 Zeta toxin Mg_chelatase PF01078.21 KIY70777.1 - 0.14 11.5 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ATP_bind_1 PF03029.17 KIY70777.1 - 0.24 11.1 0.0 0.4 10.4 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein PX PF00787.24 KIY70778.1 - 5.6e-22 77.9 0.2 1.7e-21 76.3 0.0 2.0 2 0 0 2 2 2 1 PX domain Vps5 PF09325.10 KIY70778.1 - 5.5e-06 26.1 9.1 0.001 18.7 1.6 2.1 2 0 0 2 2 2 2 Vps5 C terminal like LuxT_C PF18285.1 KIY70778.1 - 0.032 14.7 0.1 0.12 12.9 0.1 1.9 1 0 0 1 1 1 0 Tetracycline repressor LuxT C-terminal domain DUF4391 PF14335.6 KIY70778.1 - 0.06 13.0 3.3 0.037 13.7 1.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4391) DUF5339 PF17274.2 KIY70778.1 - 0.27 12.1 3.2 0.92 10.4 0.7 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5339) DUF3450 PF11932.8 KIY70778.1 - 0.34 10.2 11.2 0.02 14.2 4.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) FAM92 PF06730.11 KIY70778.1 - 0.39 10.1 3.2 0.32 10.4 0.6 2.0 2 0 0 2 2 2 0 FAM92 protein Exonuc_VII_L PF02601.15 KIY70778.1 - 0.59 9.7 4.7 4.2 6.8 1.1 2.3 2 0 0 2 2 2 0 Exonuclease VII, large subunit FapA PF03961.13 KIY70778.1 - 5.9 5.4 6.8 0.52 8.9 0.9 1.8 2 0 0 2 2 2 0 Flagellar Assembly Protein A Inositol_P PF00459.25 KIY70779.1 - 6.6e-52 176.7 0.1 3e-51 174.5 0.1 1.8 1 1 0 1 1 1 1 Inositol monophosphatase family TRAUB PF08164.12 KIY70780.1 - 2.1e-29 101.8 0.0 2.1e-29 101.8 0.0 2.2 2 1 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.6 KIY70780.1 - 1e-21 78.1 0.3 1e-21 78.1 0.3 3.1 3 0 0 3 3 3 1 Apoptosis antagonizing transcription factor Pheromone PF08015.11 KIY70780.1 - 0.36 11.9 3.4 0.53 11.4 1.1 2.5 2 1 0 2 2 2 0 Fungal mating-type pheromone CDC45 PF02724.14 KIY70780.1 - 0.77 8.0 12.2 1.2 7.3 12.2 1.3 1 0 0 1 1 1 0 CDC45-like protein SpoIIIAH PF12685.7 KIY70780.1 - 0.82 9.5 6.8 1.7 8.5 6.8 1.5 1 0 0 1 1 1 0 SpoIIIAH-like protein DUF3347 PF11827.8 KIY70780.1 - 7.2 6.8 9.4 1.1 9.5 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3347) MIF PF01187.18 KIY70781.1 - 8.2e-15 55.1 0.0 9.2e-15 54.9 0.0 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) NIR_SIR PF01077.22 KIY70783.1 - 1.2e-44 151.6 0.0 4e-40 136.9 0.0 2.5 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain Flavodoxin_1 PF00258.25 KIY70783.1 - 3.2e-27 95.5 0.0 5.5e-27 94.7 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin NIR_SIR_ferr PF03460.17 KIY70783.1 - 1.9e-21 75.7 0.0 1.1e-12 47.6 0.0 3.5 2 1 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain POR_N PF01855.19 KIY70783.1 - 1.7e-05 24.7 0.0 3.1e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg tRNA_int_endo PF01974.17 KIY70784.1 - 3.6e-17 62.2 0.2 1.1e-16 60.7 0.2 1.7 1 1 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 KIY70784.1 - 0.0035 17.0 0.0 0.1 12.3 0.0 2.3 2 0 0 2 2 2 1 tRNA intron endonuclease, N-terminal domain Actin PF00022.19 KIY70785.1 - 5.6e-36 124.0 0.0 2.4e-35 122.0 0.0 1.7 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KIY70785.1 - 0.00012 21.0 0.0 0.00024 20.0 0.0 1.4 1 0 0 1 1 1 1 MreB/Mbl protein ADH_N PF08240.12 KIY70786.1 - 3.9e-25 87.8 2.1 8.7e-25 86.7 2.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KIY70786.1 - 6.8e-12 45.5 0.0 1.2e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KIY70786.1 - 0.0026 17.3 0.2 0.025 14.1 0.2 2.0 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus NAD_binding_9 PF13454.6 KIY70786.1 - 0.099 12.6 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 FAD-NAD(P)-binding ADH_zinc_N_2 PF13602.6 KIY70786.1 - 0.12 13.4 0.0 0.4 11.7 0.0 1.9 2 0 0 2 2 2 0 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.14 KIY70786.1 - 0.17 11.5 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF4139 PF13598.6 KIY70787.1 - 6.7e-33 114.2 0.0 1.2e-31 110.1 0.0 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF4139) DUF4140 PF13600.6 KIY70787.1 - 7.6e-15 55.1 3.3 3e-14 53.2 0.5 2.4 2 0 0 2 2 2 1 N-terminal domain of unknown function (DUF4140) PDZ_2 PF13180.6 KIY70787.1 - 0.00047 20.4 1.0 0.0017 18.6 0.6 2.1 1 1 1 2 2 2 1 PDZ domain CSD2 PF17876.1 KIY70787.1 - 0.26 11.5 2.5 0.78 10.0 0.5 2.3 2 0 0 2 2 2 0 Cold shock domain Nucleoporin_FG PF13634.6 KIY70787.1 - 8.2 7.4 53.5 0.17 12.7 18.0 3.2 2 1 1 3 3 3 0 Nucleoporin FG repeat region BNR_2 PF13088.6 KIY70788.1 - 1.9e-14 53.7 3.3 2.5e-09 36.8 0.2 2.3 1 1 1 2 2 2 2 BNR repeat-like domain BNR PF02012.20 KIY70788.1 - 4.3e-05 22.9 15.3 2.3 8.6 0.2 5.1 4 0 0 4 4 4 4 BNR/Asp-box repeat BNR_3 PF13859.6 KIY70788.1 - 0.012 14.9 4.1 0.18 11.1 2.1 2.6 1 1 1 2 2 2 0 BNR repeat-like domain Sortilin-Vps10 PF15902.5 KIY70788.1 - 0.13 11.0 2.0 1.7 7.4 2.0 2.5 1 1 0 1 1 1 0 Sortilin, neurotensin receptor 3, NGP1NT PF08153.12 KIY70789.1 - 5e-49 165.8 0.1 1e-48 164.8 0.1 1.5 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 KIY70789.1 - 1.7e-17 63.6 0.1 1.9e-13 50.5 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 KIY70789.1 - 8.4e-06 25.4 0.4 0.00012 21.7 0.1 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KIY70789.1 - 8.8e-05 22.5 0.0 0.00023 21.1 0.0 1.7 1 1 0 1 1 1 1 RsgA GTPase GTP_EFTU PF00009.27 KIY70789.1 - 0.0006 19.4 0.3 0.075 12.6 0.1 2.9 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF2722 PF10846.8 KIY70789.1 - 0.014 14.3 1.7 0.026 13.5 1.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Arf PF00025.21 KIY70789.1 - 0.02 14.4 0.0 0.4 10.1 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family Roc PF08477.13 KIY70789.1 - 0.038 14.2 0.1 5.8 7.2 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 KIY70789.1 - 0.068 12.5 0.0 0.15 11.4 0.0 1.6 1 0 0 1 1 1 0 AIG1 family Nop14 PF04147.12 KIY70789.1 - 0.072 11.3 12.6 0.1 10.8 12.6 1.1 1 0 0 1 1 1 0 Nop14-like family NOG1 PF06858.14 KIY70789.1 - 0.12 12.2 0.2 0.25 11.2 0.2 1.5 1 0 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) Dynamin_N PF00350.23 KIY70789.1 - 1.9 8.5 10.2 3 7.9 0.2 4.1 3 1 1 4 4 4 0 Dynamin family CDC45 PF02724.14 KIY70789.1 - 1.9 6.7 9.7 3 6.0 9.7 1.2 1 0 0 1 1 1 0 CDC45-like protein SQHop_cyclase_N PF13249.6 KIY70790.1 - 4.3e-50 170.5 0.1 3.1e-42 144.6 0.0 3.8 3 1 1 4 4 4 2 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 KIY70790.1 - 2.1e-48 165.1 4.0 2.1e-46 158.5 2.2 2.7 2 1 1 3 3 3 3 Squalene-hopene cyclase C-terminal domain Prenyltrans PF00432.21 KIY70790.1 - 3.2e-28 97.2 9.5 6e-10 38.7 0.5 5.6 6 0 0 6 6 6 3 Prenyltransferase and squalene oxidase repeat Pec_lyase PF09492.10 KIY70790.1 - 5e-05 22.8 0.4 10 5.4 0.0 4.7 3 1 2 5 5 5 2 Pectic acid lyase DUF4817 PF16087.5 KIY70790.1 - 0.46 10.3 1.8 0.56 10.1 0.4 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain (DUF4817) Complex1_LYR PF05347.15 KIY70791.1 - 3.4e-05 23.8 2.8 0.00011 22.1 2.8 2.0 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Cnd2 PF05786.14 KIY70792.1 - 1.7e-138 463.6 11.5 3.2e-137 459.3 11.4 2.0 1 1 0 1 1 1 1 Condensin complex subunit 2 Ribosomal_L7Ae PF01248.26 KIY70793.1 - 1.2e-22 79.5 0.0 1.3e-22 79.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family LRR_4 PF12799.7 KIY70794.1 - 0.015 15.7 0.1 0.7 10.4 0.0 3.5 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KIY70794.1 - 0.085 12.8 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 F-box-like DNA_pol_B PF00136.21 KIY70795.1 - 8.7e-147 489.5 0.3 1.2e-146 489.1 0.3 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 KIY70795.1 - 3.4e-80 269.7 0.0 6.4e-80 268.8 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 KIY70795.1 - 5.9e-18 65.1 8.8 1.4e-17 63.9 8.8 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_exo2 PF10108.9 KIY70795.1 - 0.00047 19.9 0.0 0.0009 19.0 0.0 1.4 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB DNA_pol_B_2 PF03175.13 KIY70795.1 - 0.0014 17.6 0.7 0.018 14.0 0.0 2.2 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral bVLRF1 PF18826.1 KIY70796.1 - 7.1e-62 207.7 0.0 1.2e-61 207.0 0.0 1.4 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor PMM PF03332.13 KIY70797.1 - 4e-110 366.8 1.8 4.7e-110 366.6 1.8 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 KIY70797.1 - 8.3e-06 25.7 0.0 3.2e-05 23.8 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KIY70797.1 - 0.018 15.3 0.2 0.025 14.8 0.2 1.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase HAD PF12710.7 KIY70797.1 - 0.087 13.2 0.4 2.5 8.4 0.0 2.7 3 1 0 3 3 3 0 haloacid dehalogenase-like hydrolase zf-C2H2_aberr PF17017.5 KIY70798.1 - 0.001 19.2 2.3 0.018 15.2 0.5 2.4 1 1 1 2 2 2 1 Aberrant zinc-finger zf-Di19 PF05605.12 KIY70798.1 - 0.0037 17.5 2.4 0.0037 17.5 2.4 1.7 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.26 KIY70798.1 - 2.3 8.8 9.9 5.4 7.7 1.5 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type EPF PF17181.4 KIY70800.1 - 0.0046 16.9 0.4 0.0079 16.2 0.4 1.4 1 0 0 1 1 1 1 Epidermal patterning factor proteins DNA_ligase_IV PF11411.8 KIY70800.1 - 0.01 15.9 0.3 1.1 9.5 0.0 2.2 2 0 0 2 2 2 0 DNA ligase IV XPB_DRD PF18458.1 KIY70800.1 - 0.096 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Xeroderma pigmentosum group B helicase damage recognition domain MFS_1 PF07690.16 KIY70801.1 - 1.9e-33 115.9 29.7 1e-24 87.1 3.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIY70801.1 - 5.4e-13 48.6 22.2 3.6e-08 32.7 16.5 1.6 1 1 1 2 2 2 2 Sugar (and other) transporter ICMT PF04140.14 KIY70802.1 - 4.6e-14 52.6 0.1 6.7e-13 48.9 0.1 2.4 1 1 1 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KIY70802.1 - 6.5e-08 32.9 0.1 7.7e-07 29.5 0.0 2.2 2 0 0 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 KIY70802.1 - 0.0016 17.3 0.0 0.015 14.1 0.0 2.0 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 KIY70802.1 - 0.0041 16.7 0.0 0.0057 16.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) GPI-anchored PF10342.9 KIY70803.1 - 1.8e-06 28.6 1.3 9.4e-06 26.3 1.3 1.9 1 1 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF1295 PF06966.12 KIY70804.1 - 4.9e-53 180.1 2.3 6.7e-53 179.6 2.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.13 KIY70804.1 - 0.00096 19.5 2.3 0.0011 19.3 0.0 2.2 2 1 0 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.14 KIY70804.1 - 0.004 17.5 1.3 0.013 15.9 0.0 2.3 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Tim44 PF04280.15 KIY70805.1 - 8.8e-30 103.8 0.2 2.3e-29 102.4 0.2 1.8 1 0 0 1 1 1 1 Tim44-like domain CENP-F_N PF10481.9 KIY70805.1 - 0.00054 19.7 5.7 0.00082 19.1 5.7 1.2 1 0 0 1 1 1 1 Cenp-F N-terminal domain UTP15_C PF09384.10 KIY70805.1 - 0.04 13.6 2.0 5.6 6.6 0.1 3.7 3 1 0 4 4 4 0 UTP15 C terminal BORCS7 PF16088.5 KIY70805.1 - 0.084 13.1 2.8 0.093 13.0 0.2 2.4 2 1 1 3 3 3 0 BLOC-1-related complex sub-unit 7 DMPK_coil PF08826.10 KIY70805.1 - 0.085 13.0 2.6 0.13 12.4 0.3 2.4 1 1 1 2 2 2 0 DMPK coiled coil domain like Ribosomal_S20p PF01649.18 KIY70805.1 - 0.17 12.6 2.2 0.86 10.3 0.1 2.8 2 0 0 2 2 2 0 Ribosomal protein S20 DivIC PF04977.15 KIY70805.1 - 0.2 11.4 1.4 0.73 9.7 1.4 2.0 1 0 0 1 1 1 0 Septum formation initiator GARP PF16731.5 KIY70805.1 - 1.5 8.4 11.5 0.22 11.2 7.0 1.8 1 1 1 2 2 2 0 Glutamic acid/alanine-rich protein of Trypanosoma APH PF01636.23 KIY70806.1 - 1.8e-16 60.8 0.3 3.1e-16 60.1 0.3 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KIY70806.1 - 8.8e-05 22.2 0.0 0.00014 21.5 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 KIY70806.1 - 0.012 15.2 0.0 0.15 11.7 0.0 2.2 2 0 0 2 2 2 0 RIO1 family Usp PF00582.26 KIY70807.1 - 1.3e-14 54.9 0.1 2e-14 54.3 0.1 1.2 1 0 0 1 1 1 1 Universal stress protein family DUF4113 PF13438.6 KIY70807.1 - 0.073 13.2 0.0 0.61 10.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4113) EamA PF00892.20 KIY70808.1 - 3.2e-06 27.4 7.0 3.2e-06 27.4 7.0 2.1 2 0 0 2 2 2 2 EamA-like transporter family UCR_6-4kD PF08997.10 KIY70808.1 - 0.36 10.8 2.9 0.55 10.2 0.1 2.8 3 0 0 3 3 3 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein CPSase_L_D2 PF02786.17 KIY70809.1 - 8.2e-80 267.3 0.1 1.5e-79 266.4 0.1 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 KIY70809.1 - 1.4e-67 227.3 0.0 2.8e-67 226.3 0.0 1.5 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 KIY70809.1 - 4.2e-40 136.7 0.0 8.8e-40 135.7 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KIY70809.1 - 2.7e-29 101.4 0.0 8.1e-29 99.9 0.0 1.9 2 0 0 2 2 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 KIY70809.1 - 1.2e-28 100.4 0.0 2.7e-28 99.3 0.0 1.6 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 KIY70809.1 - 1.2e-16 60.3 4.6 3.3e-16 58.9 4.6 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 KIY70809.1 - 2.5e-09 36.8 4.9 0.00032 20.5 0.2 2.8 2 1 1 3 3 3 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 KIY70809.1 - 6.1e-09 35.7 0.0 1.2e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KIY70809.1 - 1e-06 28.4 0.1 2.4e-06 27.2 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 KIY70809.1 - 5.6e-06 26.5 0.0 1.3e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain HlyD_D23 PF16576.5 KIY70809.1 - 4.2e-05 22.9 1.0 0.0047 16.2 0.1 2.4 1 1 1 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 KIY70809.1 - 0.00069 20.3 1.8 1.7 9.4 0.0 2.9 2 0 0 2 2 2 2 HlyD family secretion protein GCV_H PF01597.19 KIY70809.1 - 0.0008 19.3 0.9 0.0047 16.8 0.6 2.4 2 0 0 2 2 2 1 Glycine cleavage H-protein GARS_A PF01071.19 KIY70809.1 - 0.0021 17.9 0.0 0.0041 16.9 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain NQRA PF05896.11 KIY70809.1 - 0.0021 17.5 0.4 0.0061 16.0 0.4 1.8 1 0 0 1 1 1 1 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) ATP-grasp_4 PF13535.6 KIY70809.1 - 0.0052 16.4 0.0 0.011 15.3 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain RnfC_N PF13375.6 KIY70809.1 - 0.017 15.1 0.9 0.083 12.9 1.0 2.1 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain ATPgrasp_ST PF14397.6 KIY70809.1 - 0.035 13.4 0.0 0.082 12.1 0.0 1.6 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp DUF2118 PF09891.9 KIY70809.1 - 0.053 13.5 1.0 0.74 9.8 1.1 2.5 2 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2118) LSM PF01423.22 KIY70810.1 - 1.1e-16 60.2 0.0 1.5e-16 59.8 0.0 1.1 1 0 0 1 1 1 1 LSM domain SHR3_chaperone PF08229.11 KIY70812.1 - 1.3e-42 144.9 0.3 1.4e-42 144.8 0.3 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 RhoGAP PF00620.27 KIY70813.1 - 8.2e-42 142.6 0.0 1.4e-41 141.8 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 KIY70813.1 - 4.1e-15 56.2 0.0 9e-15 55.1 0.0 1.6 1 0 0 1 1 1 1 PH domain PX PF00787.24 KIY70813.1 - 8.1e-08 32.2 0.0 2.3e-07 30.8 0.0 1.8 1 0 0 1 1 1 1 PX domain PH_8 PF15409.6 KIY70813.1 - 0.0048 17.1 0.1 0.016 15.5 0.0 1.8 2 0 0 2 2 2 1 Pleckstrin homology domain SDH_alpha PF03313.15 KIY70814.1 - 4.2e-101 338.0 2.7 5.3e-101 337.7 2.7 1.1 1 0 0 1 1 1 1 Serine dehydratase alpha chain SDH_beta PF03315.15 KIY70814.1 - 2e-58 197.2 0.0 3.7e-58 196.3 0.0 1.4 1 0 0 1 1 1 1 Serine dehydratase beta chain TMEM43 PF07787.12 KIY70816.1 - 0.046 13.1 0.0 0.047 13.1 0.0 1.0 1 0 0 1 1 1 0 Transmembrane protein 43 NARP1 PF12569.8 KIY70818.1 - 7.4e-142 473.9 9.4 6.9e-139 464.1 6.1 3.2 2 1 0 2 2 2 2 NMDA receptor-regulated protein 1 TPR_14 PF13428.6 KIY70818.1 - 1.7e-15 56.4 14.4 0.00058 20.5 0.0 9.6 8 1 1 9 9 8 3 Tetratricopeptide repeat TPR_2 PF07719.17 KIY70818.1 - 2.1e-14 52.4 24.4 0.0036 17.3 0.0 10.6 11 0 0 11 11 10 4 Tetratricopeptide repeat TPR_1 PF00515.28 KIY70818.1 - 2.1e-12 46.3 9.9 0.00029 20.5 0.3 7.4 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_11 PF13414.6 KIY70818.1 - 1.1e-10 41.0 4.2 0.0027 17.4 0.1 6.4 7 0 0 7 7 7 2 TPR repeat ANAPC3 PF12895.7 KIY70818.1 - 5e-09 36.3 6.7 0.047 13.9 0.0 6.0 4 2 2 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 KIY70818.1 - 1e-07 32.0 10.2 0.013 15.6 0.2 6.0 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_4 PF07721.14 KIY70818.1 - 2.7e-07 30.6 10.4 0.065 13.9 0.1 6.5 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 KIY70818.1 - 6.6e-07 29.9 19.8 3.9 8.2 0.0 9.0 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_19 PF14559.6 KIY70818.1 - 7.1e-07 29.7 27.4 0.017 15.6 0.1 8.0 8 2 2 10 10 8 4 Tetratricopeptide repeat TPR_12 PF13424.6 KIY70818.1 - 3.8e-06 27.1 15.5 0.072 13.4 0.8 6.7 6 2 0 6 6 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 KIY70818.1 - 6.3e-06 26.2 3.7 0.048 14.0 0.0 6.5 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_7 PF13176.6 KIY70818.1 - 1.2e-05 24.9 6.2 0.71 10.0 0.0 5.9 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 KIY70818.1 - 4.3e-05 23.4 17.4 0.041 14.1 0.0 8.1 9 0 0 9 9 7 1 Tetratricopeptide repeat PPR PF01535.20 KIY70818.1 - 0.024 14.9 0.6 27 5.3 0.0 4.8 6 0 0 6 6 5 0 PPR repeat SRP_TPR_like PF17004.5 KIY70818.1 - 0.026 14.6 4.3 1 9.4 0.0 4.7 5 2 2 7 7 6 0 Putative TPR-like repeat Fis1_TPR_C PF14853.6 KIY70818.1 - 0.027 14.6 6.9 11 6.1 0.0 5.4 6 0 0 6 6 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.6 KIY70818.1 - 0.14 12.8 24.9 5.8 7.8 0.0 8.4 10 0 0 10 10 7 0 Tetratricopeptide repeat TMEM214 PF10151.9 KIY70818.1 - 0.19 10.2 1.7 5.5 5.3 0.0 2.1 2 0 0 2 2 2 0 TMEM214, C-terminal, caspase 4 activator Nucleoporin_FG2 PF15967.5 KIY70821.1 - 0.091 11.3 2.5 0.095 11.2 2.5 1.1 1 0 0 1 1 1 0 Nucleoporin FG repeated region SPA PF08616.10 KIY70823.1 - 0.04 13.9 1.1 0.39 10.7 0.0 2.4 1 1 1 2 2 2 0 Stabilization of polarity axis p450 PF00067.22 KIY70824.1 - 2.6e-72 244.1 0.0 3.4e-72 243.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KIY70825.1 - 2.4e-72 244.2 0.0 2.9e-72 243.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 zf-RING_5 PF14634.6 KIY70826.1 - 7.3e-07 29.0 5.7 1.2e-06 28.4 5.7 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KIY70826.1 - 2.4e-06 27.3 6.0 3.6e-06 26.7 6.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIY70826.1 - 0.0004 20.2 6.9 0.0007 19.4 6.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KIY70826.1 - 0.0019 18.2 3.9 0.0042 17.1 3.9 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 KIY70826.1 - 0.0064 16.8 6.9 0.011 16.1 6.9 1.4 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 KIY70826.1 - 0.015 15.1 6.9 0.029 14.2 6.9 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KIY70826.1 - 0.12 12.3 6.2 0.25 11.2 6.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KIY70826.1 - 1.1 9.4 6.6 2.4 8.4 6.6 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 KIY70826.1 - 3.7 7.7 6.2 8.5 6.6 6.2 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-BED PF02892.15 KIY70828.1 - 0.0048 16.9 0.4 0.016 15.2 0.4 1.9 1 0 0 1 1 1 1 BED zinc finger zf-C2H2_4 PF13894.6 KIY70829.1 - 0.074 13.9 1.0 0.12 13.2 0.2 1.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KIY70829.1 - 0.51 10.9 3.3 0.36 11.4 0.5 2.0 2 0 0 2 2 2 0 Zinc-finger double domain ADH_N PF08240.12 KIY70830.1 - 1e-30 105.8 3.9 2.2e-30 104.7 3.9 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KIY70830.1 - 1.5e-15 57.4 0.0 2.6e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KIY70830.1 - 4.1e-11 42.8 0.0 5.7e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KIY70830.1 - 1.7e-06 29.1 0.0 3e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Sacchrp_dh_NADP PF03435.18 KIY70830.1 - 0.00022 21.5 0.0 0.00043 20.6 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain FAD_binding_3 PF01494.19 KIY70830.1 - 0.0013 18.0 1.1 0.002 17.4 1.1 1.3 1 0 0 1 1 1 1 FAD binding domain Staph_opine_DH PF10100.9 KIY70830.1 - 0.0094 14.6 0.0 0.012 14.2 0.0 1.1 1 0 0 1 1 1 1 Staphylopine dehydrogenase NAD_binding_7 PF13241.6 KIY70830.1 - 0.011 16.1 0.0 0.019 15.4 0.0 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding NADH_4Fe-4S PF10589.9 KIY70830.1 - 0.079 13.0 0.2 0.079 13.0 0.2 1.8 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region ADH_N_2 PF16884.5 KIY70830.1 - 0.2 11.6 0.0 0.65 9.9 0.0 1.8 2 0 0 2 2 2 0 N-terminal domain of oxidoreductase PhnA_Zn_Ribbon PF08274.12 KIY70832.1 - 0.046 13.7 0.0 0.081 12.9 0.0 1.4 1 0 0 1 1 1 0 PhnA Zinc-Ribbon Lar_restr_allev PF14354.6 KIY70832.1 - 0.17 12.3 0.7 0.35 11.3 0.7 1.4 1 0 0 1 1 1 0 Restriction alleviation protein Lar HlyIII PF03006.20 KIY70833.1 - 2e-48 165.0 18.3 2.6e-48 164.7 18.3 1.1 1 0 0 1 1 1 1 Haemolysin-III related O-FucT PF10250.9 KIY70834.1 - 4.8e-06 26.5 0.0 7.3e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase BPD_transp_1 PF00528.22 KIY70835.1 - 0.021 14.5 0.5 0.032 13.9 0.5 1.2 1 0 0 1 1 1 0 Binding-protein-dependent transport system inner membrane component Cyt-b5 PF00173.28 KIY70836.1 - 2.9e-17 62.6 0.1 5.9e-17 61.6 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 KIY70836.1 - 5.9e-14 52.6 19.5 6.1e-14 52.5 14.4 2.3 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily YppF PF14178.6 KIY70836.1 - 0.13 12.1 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 YppF-like protein Hexapep_2 PF14602.6 KIY70838.1 - 2.1e-13 49.8 4.6 2.2e-09 36.9 3.4 2.5 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.24 KIY70838.1 - 2.4e-12 46.1 4.3 4.7e-10 38.8 2.5 2.5 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Mac PF12464.8 KIY70838.1 - 3.9e-07 30.2 0.0 6.8e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Maltose acetyltransferase adh_short PF00106.25 KIY70839.1 - 2.4e-34 118.5 0.0 3.9e-29 101.5 0.0 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KIY70839.1 - 6e-22 78.3 0.0 5.7e-18 65.3 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIY70839.1 - 1.9e-08 34.4 0.0 3e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KIY70839.1 - 3.5e-07 29.9 0.0 5.2e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KIY70839.1 - 4.4e-05 22.7 0.0 6.3e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KIY70839.1 - 0.00028 20.4 0.1 0.0013 18.2 0.0 1.8 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Sacchrp_dh_NADP PF03435.18 KIY70839.1 - 0.043 14.1 0.0 0.12 12.6 0.1 1.7 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 KIY70839.1 - 0.077 13.1 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 KIY70839.1 - 0.17 11.8 0.1 0.28 11.1 0.1 1.3 1 0 0 1 1 1 0 NAD(P)H-binding Glyco_hydro_16 PF00722.21 KIY70840.1 - 0.00024 20.6 0.9 0.00024 20.6 0.9 2.0 1 1 0 2 2 2 1 Glycosyl hydrolases family 16 PATR PF12951.7 KIY70840.1 - 0.069 13.3 1.7 0.11 12.6 0.1 2.2 2 0 0 2 2 2 0 Passenger-associated-transport-repeat Abhydrolase_6 PF12697.7 KIY70841.1 - 7.1e-11 43.1 0.0 9.7e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KIY70841.1 - 3.8e-09 36.6 0.2 8.8e-09 35.4 0.2 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIY70841.1 - 0.019 14.3 0.1 0.041 13.1 0.1 1.5 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Pkinase PF00069.25 KIY70842.1 - 7.8e-41 140.2 0.0 1.2e-40 139.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY70842.1 - 3.9e-16 59.1 0.0 7.3e-16 58.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase His_Phos_2 PF00328.22 KIY70843.1 - 1.9e-18 67.0 0.0 1.8e-16 60.5 0.0 2.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Cyclin_N PF00134.23 KIY70844.1 - 9.7e-35 119.1 0.8 1.7e-34 118.3 0.8 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KIY70844.1 - 1.7e-19 70.0 0.0 6.3e-19 68.2 0.0 1.9 2 0 0 2 2 2 1 Cyclin, C-terminal domain Pro_CA PF00484.19 KIY70845.1 - 1.5e-13 51.3 0.1 4.4e-13 49.8 0.1 1.7 1 1 0 1 1 1 1 Carbonic anhydrase zf-CSL PF05207.13 KIY70846.1 - 1.7e-21 75.7 0.7 1.7e-21 75.7 0.7 1.6 2 0 0 2 2 2 1 CSL zinc finger Zn-ribbon_8 PF09723.10 KIY70846.1 - 0.0021 18.1 0.8 0.0037 17.3 0.8 1.4 1 0 0 1 1 1 1 Zinc ribbon domain GAGA PF09237.11 KIY70846.1 - 0.07 12.9 0.2 0.1 12.4 0.2 1.3 1 0 0 1 1 1 0 GAGA factor Lar_restr_allev PF14354.6 KIY70846.1 - 0.086 13.2 0.2 0.15 12.5 0.2 1.4 1 1 0 1 1 1 0 Restriction alleviation protein Lar zinc_ribbon_4 PF13717.6 KIY70846.1 - 0.097 12.6 0.5 0.16 12.0 0.5 1.3 1 0 0 1 1 1 0 zinc-ribbon domain Terminase_GpA PF05876.12 KIY70846.1 - 0.18 10.3 0.6 0.26 9.8 0.6 1.4 1 1 0 1 1 1 0 Phage terminase large subunit (GpA) Pro_CA PF00484.19 KIY70847.1 - 4.2e-14 53.1 0.4 7.4e-14 52.3 0.4 1.4 1 0 0 1 1 1 1 Carbonic anhydrase HMG_box PF00505.19 KIY70848.1 - 1.9e-10 41.0 5.3 5.1e-10 39.6 5.3 1.8 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KIY70848.1 - 0.00012 22.6 3.9 0.00041 20.9 3.9 1.9 1 0 0 1 1 1 1 HMG-box domain RhgB_N PF09284.10 KIY70849.1 - 4.5e-102 340.9 6.4 4.5e-102 340.9 6.4 1.5 2 0 0 2 2 2 1 Rhamnogalacturonan lyase B, N-terminal CBM-like PF14683.6 KIY70849.1 - 2.3e-35 121.9 0.0 7.3e-35 120.3 0.0 1.9 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.6 KIY70849.1 - 3.1e-21 74.9 2.5 1.2e-20 73.0 2.5 2.1 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.6 KIY70849.1 - 7.4e-05 22.9 1.7 0.00021 21.5 1.7 1.9 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF1522 PF07482.11 KIY70849.1 - 0.015 15.6 0.4 0.015 15.6 0.4 3.1 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1522) DUF1768 PF08719.11 KIY70850.1 - 1.2e-49 168.6 0.0 1.4e-49 168.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) SNF2_N PF00176.23 KIY70851.1 - 1.2e-56 191.9 0.3 2.6e-56 190.9 0.3 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KIY70851.1 - 1.2e-12 48.1 0.0 3.4e-12 46.7 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIY70851.1 - 1.6e-07 31.5 0.0 4.2e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4_2 PF13923.6 KIY70851.1 - 0.00026 20.8 5.8 0.00026 20.8 5.8 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIY70851.1 - 0.0022 17.8 10.1 0.0045 16.8 10.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) SWI2_SNF2 PF18766.1 KIY70851.1 - 0.0026 17.5 0.7 0.0051 16.5 0.1 1.8 2 0 0 2 2 2 1 SWI2/SNF2 ATPase zf-RING_2 PF13639.6 KIY70851.1 - 0.0051 17.1 9.0 0.011 16.0 9.0 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KIY70851.1 - 0.0091 16.0 9.3 0.025 14.6 9.3 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KIY70851.1 - 0.011 15.6 7.9 0.025 14.6 7.9 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KIY70851.1 - 2.3 8.1 11.4 7.7 6.5 11.4 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF913 PF06025.12 KIY70851.1 - 6.7 5.6 6.2 0.9 8.4 0.2 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Aldedh PF00171.22 KIY70852.1 - 1.3e-125 419.6 0.0 1.4e-125 419.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KIY70852.1 - 2.7e-06 26.7 0.0 3.8e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) Proteasome PF00227.26 KIY70853.1 - 4e-47 160.2 0.1 4.8e-47 159.9 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 KIY70853.1 - 2.3e-12 46.1 0.1 2.3e-12 46.1 0.1 1.8 2 0 0 2 2 2 1 Proteasome beta subunits C terminal NAD_Gly3P_dh_C PF07479.14 KIY70853.1 - 0.078 13.3 0.1 0.18 12.0 0.0 1.6 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus Glyco_hydro_16 PF00722.21 KIY70854.1 - 0.0039 16.7 0.0 0.0062 16.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF983 PF06170.12 KIY70855.1 - 0.46 10.9 2.2 0.3 11.5 0.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF983) F-box-like PF12937.7 KIY70856.1 - 3.7e-09 36.3 1.0 1e-08 34.9 1.0 1.8 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KIY70856.1 - 0.29 11.1 6.0 1.9 8.5 1.9 3.0 2 0 0 2 2 2 0 F-box domain CAF-1_p150 PF11600.8 KIY70857.1 - 4.6 6.9 13.3 3.3 7.4 11.5 1.5 1 1 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal HMG_box PF00505.19 KIY70858.1 - 3.3e-09 37.0 2.2 6.8e-09 36.0 2.2 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KIY70858.1 - 0.00071 20.1 1.0 0.0016 19.0 1.0 1.5 1 0 0 1 1 1 1 HMG-box domain Ribosomal_L27A PF00828.19 KIY70858.1 - 0.18 12.5 0.2 0.31 11.7 0.2 1.3 1 0 0 1 1 1 0 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A GST_N_2 PF13409.6 KIY70859.1 - 2.3e-19 69.5 0.0 4.5e-19 68.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KIY70859.1 - 2.3e-12 46.8 0.0 4.7e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KIY70859.1 - 1.7e-08 34.5 0.0 3.4e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KIY70859.1 - 9.5e-05 22.7 0.0 0.0021 18.4 0.0 2.3 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KIY70859.1 - 0.003 17.7 0.0 0.0056 16.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain QIL1 PF15884.5 KIY70859.1 - 0.078 13.6 0.0 0.92 10.1 0.0 2.3 2 0 0 2 2 2 0 MICOS complex subunit MIC13, QIL1 Pmp3 PF01679.17 KIY70860.1 - 9e-25 86.6 11.4 1.1e-24 86.3 11.4 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator CBS PF00571.28 KIY70861.1 - 7.5e-11 42.3 0.0 0.00071 20.0 0.0 2.6 2 1 1 3 3 3 2 CBS domain RNase_3_N PF18497.1 KIY70861.1 - 0.19 11.9 0.3 3.7 7.8 0.0 2.2 1 1 1 2 2 2 0 Ribonuclease III N-terminal domain AdoHcyase PF05221.17 KIY70864.1 - 1.5e-133 444.6 0.0 2e-74 250.5 0.0 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 KIY70864.1 - 1.9e-83 278.4 1.6 2.8e-83 277.8 1.6 1.2 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 KIY70864.1 - 2.7e-07 30.1 0.1 5.4e-07 29.1 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 KIY70864.1 - 0.0002 21.0 0.1 0.00033 20.3 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 KIY70864.1 - 0.0017 18.6 0.0 0.0041 17.4 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain ELFV_dehydrog PF00208.21 KIY70864.1 - 0.042 13.6 0.1 0.066 12.9 0.1 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 3HCDH_N PF02737.18 KIY70864.1 - 0.059 13.3 0.2 0.1 12.4 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 KIY70864.1 - 0.077 13.5 0.4 0.24 11.9 0.2 2.0 2 0 0 2 2 2 0 Putative NAD(P)-binding F420_oxidored PF03807.17 KIY70864.1 - 0.086 13.4 0.1 0.23 12.0 0.1 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Mitochondr_Som1 PF11093.8 KIY70865.1 - 2.1e-07 30.8 0.3 2.6e-07 30.5 0.3 1.2 1 0 0 1 1 1 1 Mitochondrial export protein Som1 Tup_N PF08581.10 KIY70866.1 - 0.13 12.6 0.8 0.24 11.7 0.8 1.3 1 0 0 1 1 1 0 Tup N-terminal TRAF_BIRC3_bd PF16673.5 KIY70866.1 - 0.21 11.4 1.0 0.41 10.5 1.0 1.4 1 0 0 1 1 1 0 TNF receptor-associated factor BIRC3 binding domain Csm1_N PF18504.1 KIY70866.1 - 0.29 11.5 1.4 0.51 10.7 1.4 1.3 1 0 0 1 1 1 0 Csm1 N-terminal domain Herpes_US12 PF05363.12 KIY70866.1 - 0.52 11.1 5.5 0.34 11.6 0.3 2.9 3 0 0 3 3 3 0 Herpesvirus US12 family GST_N PF02798.20 KIY70867.1 - 1.6e-16 60.4 0.0 3e-16 59.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KIY70867.1 - 6.1e-11 42.6 0.0 1.5e-10 41.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KIY70867.1 - 5.9e-10 39.3 0.2 1.4e-09 38.1 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KIY70867.1 - 0.084 13.1 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KIY70867.1 - 0.17 12.0 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Tht1 PF04163.12 KIY70868.1 - 5e-18 65.2 1.0 6.6e-18 64.8 1.0 1.1 1 0 0 1 1 1 1 Tht1-like nuclear fusion protein La PF05383.17 KIY70869.1 - 2e-16 59.8 0.0 3.2e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 La domain PPP4R2 PF09184.11 KIY70869.1 - 4.8 6.7 6.1 9.6 5.7 6.1 1.5 1 0 0 1 1 1 0 PPP4R2 Pmp3 PF01679.17 KIY70870.1 - 2.7e-21 75.5 11.7 3.4e-21 75.2 11.7 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator NapE PF06796.11 KIY70870.1 - 0.089 12.3 0.4 0.19 11.2 0.4 1.5 1 0 0 1 1 1 0 Periplasmic nitrate reductase protein NapE RRF PF01765.19 KIY70871.1 - 5e-28 98.1 0.2 9.4e-28 97.2 0.2 1.4 1 0 0 1 1 1 1 Ribosome recycling factor CDC14 PF08045.11 KIY70871.1 - 0.1 11.7 0.2 0.16 11.0 0.2 1.2 1 0 0 1 1 1 0 Cell division control protein 14, SIN component Mito_carr PF00153.27 KIY70872.1 - 2.4e-59 197.2 0.5 8.1e-21 73.8 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein G-alpha PF00503.20 KIY70873.1 - 7.3e-111 370.7 0.0 8.7e-111 370.5 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KIY70873.1 - 5.5e-11 42.2 0.1 5.9e-07 29.1 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family AAA_29 PF13555.6 KIY70873.1 - 0.0055 16.4 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain TniB PF05621.11 KIY70873.1 - 0.013 14.9 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Gtr1_RagA PF04670.12 KIY70873.1 - 0.029 13.7 0.1 6.9 5.9 0.1 2.3 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region Roc PF08477.13 KIY70873.1 - 0.054 13.7 0.0 2.5 8.4 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Pkinase PF00069.25 KIY70874.1 - 3e-70 236.6 0.0 3.7e-70 236.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY70874.1 - 2.3e-32 112.3 0.0 3e-32 111.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY70874.1 - 1.1e-05 24.9 0.0 1.7e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KIY70874.1 - 4.3e-05 22.9 0.0 7.7e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KIY70874.1 - 0.00052 18.9 0.0 0.00098 18.0 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KIY70874.1 - 0.0011 19.0 0.0 0.013 15.4 0.0 2.2 1 1 0 2 2 2 1 Phosphotransferase enzyme family Protoglobin PF11563.8 KIY70875.1 - 3.3e-38 131.1 0.1 3.9e-38 130.8 0.1 1.1 1 0 0 1 1 1 1 Protoglobin Pkinase PF00069.25 KIY70876.1 - 4.4e-26 91.8 0.0 5.1e-26 91.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY70876.1 - 3.7e-23 82.1 0.0 4e-23 82.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Glyco_hydro_28 PF00295.17 KIY70879.1 - 3.4e-56 190.7 20.0 4.3e-56 190.3 20.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 DUF1565 PF07602.11 KIY70879.1 - 4.9e-07 29.4 4.3 1e-06 28.3 4.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1565) CYSTM PF12734.7 KIY70880.1 - 2.7e-07 30.8 41.6 0.0024 18.2 41.6 2.8 1 1 0 1 1 1 1 Cysteine-rich TM module stress tolerance Na_Ca_ex PF01699.24 KIY70881.1 - 9.2e-36 123.1 31.2 1.8e-19 70.2 12.7 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF1129 PF06570.11 KIY70881.1 - 0.017 14.6 0.6 0.017 14.6 0.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Otopetrin PF03189.13 KIY70881.1 - 0.23 10.2 1.6 0.44 9.3 1.6 1.4 1 0 0 1 1 1 0 Otopetrin Pox_A14 PF05767.12 KIY70881.1 - 5.2 7.3 7.7 0.59 10.3 0.1 3.2 3 1 0 3 3 3 0 Poxvirus virion envelope protein A14 Zn_clus PF00172.18 KIY70882.1 - 1.4e-07 31.5 11.4 2.2e-07 30.9 11.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Rhodopsin_N PF10413.9 KIY70883.1 - 0.12 12.3 0.2 0.84 9.5 0.0 2.1 2 0 0 2 2 2 0 Amino terminal of the G-protein receptor rhodopsin DUF2017 PF09438.10 KIY70885.1 - 0.064 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2017) Peptidase_S15 PF02129.18 KIY70887.1 - 5e-07 29.6 0.1 2e-06 27.6 0.0 1.8 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 KIY70887.1 - 0.0031 17.0 0.0 0.0057 16.2 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KIY70887.1 - 0.0032 17.2 0.1 0.0052 16.5 0.1 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 KIY70887.1 - 0.034 13.8 0.0 0.21 11.2 0.0 1.9 1 1 0 1 1 1 0 Putative esterase DNA_RNApol_7kD PF03604.13 KIY70888.1 - 5.4e-17 61.2 5.6 6.9e-17 60.8 5.6 1.1 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit zinc_ribbon_10 PF10058.9 KIY70888.1 - 0.0033 17.1 0.5 0.15 11.8 0.1 2.2 2 0 0 2 2 2 1 Predicted integral membrane zinc-ribbon metal-binding protein MCM_OB PF17207.3 KIY70888.1 - 0.005 16.7 0.3 0.0051 16.7 0.3 1.1 1 0 0 1 1 1 1 MCM OB domain Anti-TRAP PF15777.5 KIY70888.1 - 0.02 14.9 0.1 0.026 14.5 0.1 1.3 1 0 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein zinc-ribbon_6 PF10005.9 KIY70888.1 - 0.022 15.4 0.7 0.13 12.9 1.0 1.8 1 1 1 2 2 2 0 zinc-ribbon domain DZR PF12773.7 KIY70888.1 - 0.023 14.7 0.7 0.032 14.2 0.7 1.3 1 0 0 1 1 1 0 Double zinc ribbon zf_UBZ PF18439.1 KIY70888.1 - 0.029 14.0 1.9 3.6 7.3 0.1 2.2 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 KIY70888.1 - 0.029 14.5 2.4 0.057 13.5 2.4 1.5 1 1 0 1 1 1 0 Zinc ribbon domain HypA PF01155.19 KIY70888.1 - 0.034 14.2 0.4 0.037 14.1 0.4 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_4 PF13717.6 KIY70888.1 - 0.2 11.6 3.6 2.5 8.1 3.6 2.1 1 1 0 1 1 1 0 zinc-ribbon domain zf-trcl PF13451.6 KIY70888.1 - 0.22 11.4 5.4 4.5 7.2 0.2 2.2 1 1 1 2 2 2 0 Probable zinc-ribbon domain Zn_ribbon_recom PF13408.6 KIY70888.1 - 0.33 11.5 0.5 0.33 11.5 0.5 2.4 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain Glyco_transf_15 PF01793.16 KIY70889.1 - 3.7e-129 430.6 5.6 4.4e-129 430.4 5.6 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Glyco_transf_15 PF01793.16 KIY70890.1 - 7.8e-124 413.1 8.6 9.6e-124 412.8 8.6 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Porin_3 PF01459.22 KIY70891.1 - 3.9e-72 243.0 1.3 4.6e-72 242.7 1.3 1.0 1 0 0 1 1 1 1 Eukaryotic porin F-box-like PF12937.7 KIY70892.1 - 0.015 15.2 1.3 0.032 14.1 0.1 2.3 2 0 0 2 2 2 0 F-box-like SpoIIE PF07228.12 KIY70893.1 - 3.7e-08 33.5 0.0 8.4e-08 32.4 0.0 1.6 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 KIY70893.1 - 0.0015 18.2 0.0 0.0029 17.3 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C DNA_pol3_gamma3 PF12169.8 KIY70893.1 - 0.18 11.7 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III subunits gamma and tau domain III TPR_19 PF14559.6 KIY70894.1 - 0.0031 18.0 0.2 0.0031 18.0 0.2 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat Sel1 PF08238.12 KIY70894.1 - 0.011 16.5 1.0 2.1 9.1 0.1 3.2 2 0 0 2 2 2 0 Sel1 repeat TPR_12 PF13424.6 KIY70894.1 - 0.016 15.5 9.2 0.75 10.1 0.3 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 KIY70894.1 - 0.056 13.6 5.0 0.17 12.0 0.1 4.1 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF2225 PF09986.9 KIY70894.1 - 0.079 12.7 0.0 0.59 9.8 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) DUF29 PF01724.16 KIY70894.1 - 0.15 12.2 0.6 0.76 10.0 0.5 2.2 1 1 1 2 2 2 0 Domain of unknown function DUF29 TPR_10 PF13374.6 KIY70894.1 - 0.88 9.5 4.4 31 4.6 0.6 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KIY70894.1 - 1.5 9.9 11.3 6.7 7.8 0.4 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat p450 PF00067.22 KIY70895.1 - 3.8e-75 253.4 0.0 4.2e-75 253.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TMEM191C PF15194.6 KIY70896.1 - 0.01 16.0 6.2 0.07 13.3 0.4 2.4 2 0 0 2 2 2 0 TMEM191C family DUF563 PF04577.14 KIY70898.1 - 2.9e-08 34.1 0.0 6.2e-08 33.0 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF563) XdhC_C PF13478.6 KIY70898.1 - 0.13 12.7 0.1 0.41 11.1 0.1 1.9 1 0 0 1 1 1 0 XdhC Rossmann domain DUF4164 PF13747.6 KIY70899.1 - 1.5 9.1 16.2 2.4 8.5 4.8 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) APG6_N PF17675.1 KIY70899.1 - 4.1 7.9 16.1 0.92 10.0 0.4 2.7 2 1 0 2 2 2 0 Apg6 coiled-coil region AAA_12 PF13087.6 KIY70900.1 - 1.4e-34 119.5 0.0 2.5e-34 118.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KIY70900.1 - 9.5e-28 97.7 0.0 3.5e-27 95.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KIY70900.1 - 5e-10 39.4 0.2 9.8e-05 22.1 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.6 KIY70900.1 - 3.6e-07 30.6 0.1 1.2e-05 25.7 0.1 2.4 1 1 0 1 1 1 1 AAA domain zf-CCCH_4 PF18044.1 KIY70900.1 - 2.5e-06 27.2 2.8 2.5e-06 27.2 2.8 3.6 3 0 0 3 3 3 2 CCCH-type zinc finger zf-CCCH PF00642.24 KIY70900.1 - 0.00034 20.4 3.3 0.00034 20.4 3.3 4.0 4 0 0 4 4 4 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF2075 PF09848.9 KIY70900.1 - 0.00053 19.3 0.1 1.1 8.4 0.0 3.3 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) zf_CCCH_4 PF18345.1 KIY70900.1 - 0.0041 17.1 3.8 0.0041 17.1 3.8 3.8 3 0 0 3 3 3 2 Zinc finger domain AAA_22 PF13401.6 KIY70900.1 - 0.025 14.8 0.1 4.1 7.7 0.0 3.0 2 0 0 2 2 2 0 AAA domain DUF4618 PF15397.6 KIY70900.1 - 9.2 5.6 6.4 2.1 7.7 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4618) RAI16-like PF10257.9 KIY70901.1 - 1.1e-71 241.6 0.0 1.5e-71 241.2 0.0 1.2 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein DnaJ PF00226.31 KIY70902.1 - 7e-20 70.9 0.1 2.1e-19 69.4 0.1 1.9 1 0 0 1 1 1 1 DnaJ domain PAP2 PF01569.21 KIY70903.1 - 3e-10 40.0 14.8 1.2e-07 31.6 13.2 2.6 1 1 0 1 1 1 1 PAP2 superfamily DUF212 PF02681.14 KIY70903.1 - 0.00086 19.4 0.7 0.019 15.1 0.1 2.5 2 0 0 2 2 2 1 Divergent PAP2 family MRP-L20 PF12824.7 KIY70904.1 - 8.1e-17 61.9 4.6 1.1e-16 61.5 4.6 1.4 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 SMC_N PF02463.19 KIY70905.1 - 1.3e-28 100.0 0.0 6.4e-28 97.7 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KIY70905.1 - 2e-10 41.5 28.7 2e-10 41.5 28.7 5.2 3 2 0 3 3 3 1 AAA domain AAA_15 PF13175.6 KIY70905.1 - 3.3e-10 40.2 0.1 3.3e-10 40.2 0.1 3.2 2 2 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 KIY70905.1 - 7.2e-07 29.3 0.1 0.0014 18.5 0.2 3.0 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KIY70905.1 - 0.00031 20.4 0.1 0.0013 18.5 0.0 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC_tran PF00005.27 KIY70905.1 - 0.077 13.5 0.0 0.077 13.5 0.0 5.2 4 2 1 5 5 5 0 ABC transporter E1_dh PF00676.20 KIY70906.1 - 9.1e-87 290.8 0.0 1.2e-86 290.4 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TP_methylase PF00590.20 KIY70908.1 - 1.5e-21 77.3 0.0 2.2e-21 76.8 0.0 1.2 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases F-box PF00646.33 KIY70909.1 - 0.0035 17.2 0.1 0.014 15.2 0.1 2.0 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KIY70909.1 - 0.0089 15.9 0.2 0.0089 15.9 0.2 2.8 3 0 0 3 3 3 1 F-box-like DUF3638 PF12340.8 KIY70910.1 - 8e-79 264.1 0.3 1.7e-78 263.1 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 KIY70910.1 - 4.6e-17 61.1 0.4 1.2e-16 59.8 0.4 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) Apolipoprotein PF01442.18 KIY70910.1 - 0.28 11.0 3.0 0.5 10.2 0.0 2.9 3 0 0 3 3 3 0 Apolipoprotein A1/A4/E domain DUF3552 PF12072.8 KIY70911.1 - 0.0048 16.3 5.3 0.033 13.6 1.9 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF3552) DUF4013 PF13197.6 KIY70911.1 - 0.04 13.8 0.0 0.058 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4013) DUF1090 PF06476.12 KIY70911.1 - 0.12 12.5 2.5 6.4 6.9 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1090) DUF2418 PF10332.9 KIY70912.1 - 1.7e-28 98.9 0.7 3.1e-28 98.1 0.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2418) zf-RING_2 PF13639.6 KIY70913.1 - 2.4e-09 37.4 10.6 4.1e-09 36.6 10.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KIY70913.1 - 3.6e-09 36.4 9.9 6.3e-09 35.6 9.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KIY70913.1 - 3.9e-09 36.2 9.4 6.4e-09 35.5 9.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KIY70913.1 - 3.6e-08 33.1 5.4 5.7e-08 32.5 5.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KIY70913.1 - 4.2e-06 27.0 7.3 1e-05 25.7 7.3 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KIY70913.1 - 4.5e-06 26.6 7.6 8.7e-06 25.7 7.6 1.5 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KIY70913.1 - 2.7e-05 23.9 7.2 4.9e-05 23.1 7.2 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KIY70913.1 - 7.7e-05 22.6 9.2 0.00013 21.9 9.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KIY70913.1 - 0.023 14.7 2.8 0.047 13.8 2.8 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 KIY70913.1 - 0.026 14.7 10.4 0.045 13.9 10.4 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 KIY70913.1 - 0.055 13.2 8.0 0.11 12.3 8.0 1.5 1 0 0 1 1 1 0 RING-like zinc finger Siva PF05458.12 KIY70913.1 - 0.1 12.2 3.6 0.5 10.0 2.9 2.0 2 0 0 2 2 2 0 Cd27 binding protein (Siva) zf-RING_10 PF16685.5 KIY70913.1 - 0.35 11.0 4.1 0.67 10.1 4.1 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_6 PF14835.6 KIY70913.1 - 0.84 9.5 4.8 1.5 8.7 4.8 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein IBR PF01485.21 KIY70913.1 - 2.5 8.4 9.1 2.8 8.2 7.4 2.0 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain Pkinase PF00069.25 KIY70914.1 - 5e-25 88.4 0.0 7e-25 87.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY70914.1 - 7e-14 51.7 0.0 1.8e-13 50.4 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase DEAD_2 PF06733.15 KIY70915.1 - 2.4e-51 173.8 0.0 4.7e-51 172.9 0.0 1.5 1 0 0 1 1 1 1 DEAD_2 HBB PF06777.11 KIY70915.1 - 2e-44 151.5 2.1 8.6e-39 133.2 0.3 2.5 2 0 0 2 2 2 2 Helical and beta-bridge domain Helicase_C_2 PF13307.6 KIY70915.1 - 1.3e-43 149.2 0.0 2.5e-43 148.2 0.0 1.5 1 0 0 1 1 1 1 Helicase C-terminal domain ResIII PF04851.15 KIY70915.1 - 0.0019 18.2 0.9 0.083 12.9 0.0 2.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Meis_PKNOX_N PF16493.5 KIY70915.1 - 0.09 13.1 0.0 3.2 8.1 0.0 2.6 2 0 0 2 2 2 0 N-terminal of Homeobox Meis and PKNOX1 Glucan_synthase PF02364.15 KIY70916.1 - 0 1300.5 0.0 0 1300.0 0.0 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 KIY70916.1 - 1.5e-43 148.2 0.1 4.2e-43 146.8 0.1 1.8 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 zf-CCCH PF00642.24 KIY70917.1 - 0.0051 16.7 2.1 0.0082 16.0 2.1 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Seryl_tRNA_N PF02403.22 KIY70917.1 - 0.012 15.8 14.5 0.18 12.1 4.5 3.6 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain EzrA PF06160.12 KIY70917.1 - 0.039 12.1 11.2 0.081 11.1 4.3 2.3 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA Rh5 PF18515.1 KIY70917.1 - 0.11 11.7 1.4 4.5 6.5 0.0 2.9 3 0 0 3 3 3 0 Rh5 coiled-coil domain FUSC PF04632.12 KIY70917.1 - 0.13 10.8 9.5 1.4 7.3 0.1 2.1 1 1 1 2 2 2 0 Fusaric acid resistance protein family SHE3 PF17078.5 KIY70917.1 - 0.23 11.2 8.5 0.3 10.8 5.6 2.4 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 Exonuc_VII_L PF02601.15 KIY70917.1 - 0.44 10.1 11.7 0.17 11.4 8.9 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit Spore_III_AB PF09548.10 KIY70917.1 - 0.92 9.6 8.0 0.22 11.6 2.7 2.3 1 1 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) GrpE PF01025.19 KIY70917.1 - 1.1 9.0 15.5 0.39 10.4 7.3 2.4 1 1 1 2 2 2 0 GrpE V_ATPase_I PF01496.19 KIY70917.1 - 1.9 6.3 8.2 3.2 5.5 8.2 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Sec34 PF04136.15 KIY70917.1 - 2.2 8.2 8.6 1.4 8.8 5.2 2.2 2 0 0 2 2 2 0 Sec34-like family Atg14 PF10186.9 KIY70917.1 - 9.7 5.2 10.3 1.5 7.9 0.9 2.2 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Peptidase_M41 PF01434.18 KIY70919.1 - 2.5e-52 177.5 0.1 5.1e-52 176.5 0.1 1.5 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 KIY70919.1 - 7.3e-43 146.2 0.0 2e-42 144.7 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KIY70919.1 - 1.1e-09 37.9 0.0 3e-09 36.5 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 KIY70919.1 - 6.4e-05 22.8 0.1 0.00029 20.6 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KIY70919.1 - 8.4e-05 22.6 0.0 0.00034 20.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KIY70919.1 - 0.0001 22.8 4.3 0.0019 18.6 0.1 3.0 2 1 0 3 3 3 1 AAA ATPase domain TIP49 PF06068.13 KIY70919.1 - 0.00015 21.1 0.0 0.00026 20.3 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 KIY70919.1 - 0.00036 20.8 0.2 0.0054 17.0 0.2 2.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KIY70919.1 - 0.0046 17.1 0.0 0.016 15.3 0.0 2.0 2 0 0 2 2 1 1 AAA domain Mg_chelatase PF01078.21 KIY70919.1 - 0.006 16.0 0.3 0.013 14.9 0.3 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 KIY70919.1 - 0.0063 17.1 0.0 0.021 15.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KIY70919.1 - 0.0064 16.8 0.1 0.031 14.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KIY70919.1 - 0.0096 15.7 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Sigma54_activat PF00158.26 KIY70919.1 - 0.013 15.3 0.3 0.59 9.8 0.0 2.5 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_25 PF13481.6 KIY70919.1 - 0.014 15.0 5.7 0.21 11.1 0.4 2.9 2 1 1 3 3 3 0 AAA domain AAA_2 PF07724.14 KIY70919.1 - 0.035 14.2 0.0 0.097 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) NACHT PF05729.12 KIY70919.1 - 0.037 13.9 0.1 0.18 11.7 0.1 2.1 2 0 0 2 2 2 0 NACHT domain AAA_7 PF12775.7 KIY70919.1 - 0.043 13.3 0.1 0.21 11.1 0.1 2.0 1 1 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 KIY70919.1 - 0.052 13.6 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 KIY70919.1 - 0.054 12.7 0.0 0.12 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_17 PF13207.6 KIY70919.1 - 0.094 13.1 0.5 0.39 11.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 KIY70919.1 - 0.19 11.1 0.2 0.89 8.9 0.0 2.1 2 0 0 2 2 2 0 KaiC DUF1180 PF06679.12 KIY70919.1 - 0.34 11.3 2.6 0.63 10.4 2.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) GCIP PF13324.6 KIY70920.1 - 3.3e-31 108.9 0.0 3.9e-31 108.6 0.0 1.1 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting GIT1_C PF12205.8 KIY70920.1 - 0.024 14.7 0.1 0.32 11.1 0.0 2.3 2 0 0 2 2 2 0 G protein-coupled receptor kinase-interacting protein 1 C term DUF3348 PF11828.8 KIY70921.1 - 0.0041 16.8 2.2 0.0065 16.2 2.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3348) PBP1_TM PF14812.6 KIY70921.1 - 9.7 6.6 9.6 56 4.2 9.6 2.4 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FBPase PF00316.20 KIY70922.1 - 1.2e-74 249.9 0.9 1.6e-74 249.5 0.9 1.2 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Inositol_P PF00459.25 KIY70922.1 - 0.002 17.7 0.0 0.0039 16.7 0.0 1.4 1 0 0 1 1 1 1 Inositol monophosphatase family zf-H2C2_2 PF13465.6 KIY70923.1 - 4.6e-23 80.6 30.2 4.7e-09 36.3 0.1 6.2 6 0 0 6 6 6 3 Zinc-finger double domain zf-C2H2 PF00096.26 KIY70923.1 - 8.8e-19 66.8 37.7 5.1e-05 23.5 0.4 4.9 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIY70923.1 - 9.5e-11 41.6 31.4 0.0068 17.2 0.6 5.0 5 0 0 5 5 5 4 C2H2-type zinc finger zf-met PF12874.7 KIY70923.1 - 2.3e-05 24.6 10.4 0.18 12.2 0.2 4.1 4 0 0 4 4 4 3 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KIY70923.1 - 0.0002 21.1 16.5 0.0046 16.7 0.5 4.5 4 0 0 4 4 4 2 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KIY70923.1 - 0.00053 20.2 8.6 0.9 9.9 0.4 4.2 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 KIY70923.1 - 0.00093 19.8 4.0 0.17 12.5 0.5 3.2 2 1 1 3 3 3 1 FOXP coiled-coil domain DUF448 PF04296.13 KIY70923.1 - 0.059 13.2 0.1 6.3 6.7 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF448) SDP_N PF12278.8 KIY70923.1 - 0.23 11.6 2.0 0.77 9.9 2.0 1.8 1 0 0 1 1 1 0 Sex determination protein N terminal zf-C2H2_aberr PF17017.5 KIY70923.1 - 3.1 7.9 6.9 38 4.4 0.0 3.4 2 1 1 4 4 4 0 Aberrant zinc-finger PE PF00934.20 KIY70923.1 - 6.4 7.2 10.5 3.3 8.1 7.3 2.0 2 0 0 2 2 2 0 PE family zf-CGNR PF11706.8 KIY70923.1 - 8.6 6.3 12.6 34 4.4 0.1 4.0 3 1 0 3 3 3 0 CGNR zinc finger zf-LYAR PF08790.11 KIY70923.1 - 9.5 6.2 8.0 81 3.2 0.1 4.1 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger Pmp3 PF01679.17 KIY70924.1 - 6.1e-15 55.2 3.0 8.1e-15 54.8 3.0 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator rve_3 PF13683.6 KIY70924.1 - 0.03 14.1 0.2 0.063 13.1 0.2 1.6 1 0 0 1 1 1 0 Integrase core domain AAA_21 PF13304.6 KIY70924.1 - 0.05 13.4 1.2 0.064 13.1 1.2 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system PNGaseA PF12222.8 KIY70925.1 - 1.7e-133 445.7 0.5 2.4e-133 445.2 0.5 1.1 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A PCI PF01399.27 KIY70926.1 - 3.3e-16 59.7 0.7 1.1e-15 58.0 0.1 2.2 3 0 0 3 3 3 1 PCI domain eIF3m_C_helix PF18005.1 KIY70926.1 - 1.2e-13 50.4 0.6 2.7e-13 49.4 0.6 1.6 1 0 0 1 1 1 1 eIF3 subunit M, C-terminal helix Rrf2 PF02082.20 KIY70926.1 - 0.081 13.3 0.1 0.26 11.7 0.1 1.8 1 1 1 2 2 2 0 Transcriptional regulator tRNA-synt_2d PF01409.20 KIY70927.1 - 1e-46 159.4 0.1 1.1e-26 93.8 0.0 2.1 1 1 1 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 KIY70927.1 - 1.7e-22 79.6 0.0 4e-22 78.4 0.0 1.7 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain Med17 PF10156.9 KIY70927.1 - 0.027 13.2 0.0 0.027 13.2 0.0 1.1 1 0 0 1 1 1 0 Subunit 17 of Mediator complex PI3_PI4_kinase PF00454.27 KIY70928.1 - 1.1e-33 117.1 0.0 1.6e-32 113.3 0.0 2.2 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.8 KIY70928.1 - 0.0009 19.2 0.1 0.011 15.7 0.0 2.8 3 0 0 3 3 3 1 Yeast phosphatidylinositol-4-OH kinase Pik1 DUF4135 PF13575.6 KIY70928.1 - 0.081 12.2 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) OST3_OST6 PF04756.13 KIY70929.1 - 3.2e-92 309.0 0.0 3.7e-92 308.8 0.0 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin PF00085.20 KIY70929.1 - 0.00013 21.9 0.0 0.00021 21.3 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_6 PF13848.6 KIY70929.1 - 0.13 12.2 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain GrpE PF01025.19 KIY70930.1 - 4.7e-42 143.5 0.0 6.2e-42 143.1 0.0 1.1 1 0 0 1 1 1 1 GrpE FTHFS PF01268.19 KIY70931.1 - 2.2e-254 844.8 0.1 4.7e-254 843.7 0.0 1.6 2 0 0 2 2 2 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 KIY70931.1 - 2.1e-64 215.7 1.1 2.1e-64 215.7 1.1 2.0 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 KIY70931.1 - 6.6e-35 119.9 0.1 1.4e-34 118.8 0.1 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain OCD_Mu_crystall PF02423.15 KIY70931.1 - 0.018 14.0 0.1 0.035 13.0 0.1 1.4 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family Alpha-amylase PF00128.24 KIY70932.1 - 3.3e-17 63.1 5.1 4.4e-16 59.4 1.3 3.3 2 1 0 2 2 2 1 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.11 KIY70932.1 - 1.8e-14 54.0 0.0 1.8e-14 54.0 0.0 1.7 2 0 0 2 2 2 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 KIY70932.1 - 2.9e-07 30.2 0.0 5.4e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Pkinase PF00069.25 KIY70933.1 - 2.2e-69 233.8 0.0 3e-69 233.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY70933.1 - 1.1e-46 159.3 0.0 1.6e-46 158.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase SAM_2 PF07647.17 KIY70933.1 - 8.7e-14 51.4 0.1 1.7e-13 50.5 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KIY70933.1 - 1.5e-10 41.4 0.1 3.1e-10 40.4 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ras_bdg_2 PF14847.6 KIY70933.1 - 2.6e-07 30.9 0.0 5e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Ras-binding domain of Byr2 Kinase-like PF14531.6 KIY70933.1 - 4.7e-06 26.1 0.0 0.00031 20.1 0.0 2.5 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KIY70933.1 - 7.3e-05 21.7 0.7 0.00011 21.1 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase SAM_4 PF18017.1 KIY70933.1 - 0.017 15.1 0.0 0.034 14.1 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Kdo PF06293.14 KIY70933.1 - 0.098 12.0 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SDA1 PF05285.12 KIY70933.1 - 0.56 9.6 10.5 0.87 8.9 10.5 1.2 1 0 0 1 1 1 0 SDA1 MaoC_dehydratas PF01575.19 KIY70934.1 - 0.0074 15.8 0.0 0.017 14.7 0.0 1.6 1 0 0 1 1 1 1 MaoC like domain Histone PF00125.24 KIY70935.1 - 7.7e-23 81.3 2.9 1e-22 80.9 2.9 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KIY70935.1 - 3.3e-05 24.1 0.1 6.8e-05 23.1 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KIY70935.1 - 0.00041 20.8 0.0 0.00064 20.2 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DUF1018 PF06252.12 KIY70935.1 - 0.024 15.6 0.3 0.041 14.9 0.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1018) YscO-like PF16789.5 KIY70935.1 - 0.044 13.8 0.1 0.052 13.6 0.1 1.1 1 0 0 1 1 1 0 YscO-like protein ORC6 PF05460.13 KIY70935.1 - 0.58 9.4 7.0 0.73 9.0 7.0 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) PRCC PF10253.9 KIY70936.1 - 1.9e-24 87.7 12.4 1.9e-24 87.7 12.4 2.8 2 2 0 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting Cellulase PF00150.18 KIY70937.1 - 3e-15 56.4 0.9 3e-15 56.4 0.9 2.1 2 0 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) tRNA-synt_1d PF00750.19 KIY70938.1 - 5.7e-92 308.3 3.4 2.8e-52 177.8 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (R) DALR_1 PF05746.15 KIY70938.1 - 3.3e-21 75.7 0.1 7.3e-21 74.6 0.1 1.6 1 0 0 1 1 1 1 DALR anticodon binding domain DUF2828 PF11443.8 KIY70939.1 - 1.1e-217 724.1 0.0 1.3e-217 723.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) Prok-RING_2 PF14445.6 KIY70939.1 - 0.14 12.4 0.0 19 5.5 0.0 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 2 FoP_duplication PF13865.6 KIY70939.1 - 9.9 6.8 7.8 20 5.8 7.8 1.4 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 RRM_1 PF00076.22 KIY70940.1 - 1.6e-09 37.4 0.0 5.5e-06 26.1 0.0 2.9 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PUF PF00806.19 KIY70941.1 - 3.1e-67 218.7 1.2 3e-10 39.2 0.0 8.2 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Kinesin PF00225.23 KIY70942.1 - 4.5e-111 371.0 2.7 6.7e-111 370.4 0.4 2.4 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KIY70942.1 - 1e-27 96.9 0.0 4.6e-27 94.8 0.0 2.2 1 0 0 1 1 1 1 Microtubule binding DUF465 PF04325.13 KIY70942.1 - 7.6e-07 29.1 2.5 7.6e-07 29.1 2.5 3.2 2 0 0 2 2 2 1 Protein of unknown function (DUF465) Tropomyosin_1 PF12718.7 KIY70942.1 - 0.012 15.7 4.1 0.012 15.7 4.1 6.5 2 1 4 7 7 7 0 Tropomyosin like TFA2_Winged_2 PF18121.1 KIY70942.1 - 0.077 12.7 1.1 1.7 8.4 0.4 3.6 3 0 0 3 3 3 0 TFA2 Winged helix domain 2 DUF272 PF03312.15 KIY70942.1 - 0.92 9.8 3.2 1.1 9.5 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF272) Pro_Al_protease PF02983.14 KIY70942.1 - 4.5 7.4 5.9 3.4 7.8 1.7 3.2 2 0 0 2 2 2 0 Alpha-lytic protease prodomain Elf1 PF05129.13 KIY70943.1 - 7.6e-28 96.4 2.1 8.4e-28 96.2 2.1 1.0 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like zf-CHY PF05495.12 KIY70943.1 - 0.019 15.4 1.5 0.026 15.0 1.5 1.2 1 0 0 1 1 1 0 CHY zinc finger PHD_4 PF16866.5 KIY70943.1 - 0.021 14.9 0.3 0.027 14.6 0.3 1.3 1 0 0 1 1 1 0 PHD-finger GAIN_A PF18619.1 KIY70943.1 - 0.091 13.0 0.8 0.14 12.4 0.8 1.3 1 0 0 1 1 1 0 GPCR-Autoproteolysis-INducing (GAIN) subdomain A zf-Sec23_Sec24 PF04810.15 KIY70943.1 - 0.16 12.1 3.4 1.4 9.0 0.4 2.3 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger DEAD PF00270.29 KIY70944.1 - 8.1e-10 38.7 0.0 9.7e-10 38.5 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase MFS_1 PF07690.16 KIY70945.1 - 2.4e-40 138.6 43.4 2.9e-40 138.3 36.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIY70945.1 - 1.2e-14 54.1 6.5 1.2e-14 54.1 6.5 1.8 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 KIY70945.1 - 5.9e-11 41.5 1.8 5.9e-11 41.5 1.8 1.4 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 KIY70945.1 - 4.1e-07 29.6 2.8 4.1e-07 29.6 2.8 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB MFS_1 PF07690.16 KIY70946.1 - 2.4e-39 135.3 17.0 2.4e-39 135.3 17.0 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIY70946.1 - 3.8e-13 49.1 5.3 3.8e-13 49.1 5.3 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 KIY70946.1 - 6.5e-09 34.8 3.6 6.5e-09 34.8 3.6 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 KIY70946.1 - 1e-05 25.0 3.8 1e-05 25.0 3.8 2.4 3 0 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB FPN1 PF06963.12 KIY70946.1 - 0.009 14.6 0.1 0.009 14.6 0.1 1.5 2 0 0 2 2 2 1 Ferroportin1 (FPN1) Wzy_C PF04932.15 KIY70946.1 - 0.12 12.1 0.1 0.12 12.1 0.1 3.7 3 2 0 3 3 3 0 O-Antigen ligase ANAPC4_WD40 PF12894.7 KIY70948.1 - 5.2e-11 42.7 0.0 0.0019 18.4 0.0 5.6 4 2 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KIY70948.1 - 5.1e-08 33.4 0.6 0.019 15.8 0.1 5.2 4 0 0 4 4 4 2 WD domain, G-beta repeat eIF2A PF08662.11 KIY70948.1 - 0.00026 20.9 0.0 0.31 10.9 0.0 4.3 3 2 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 KIY70948.1 - 0.0095 14.5 0.0 0.27 9.7 0.0 2.8 3 0 0 3 3 3 1 Cytochrome D1 heme domain Nbas_N PF15492.6 KIY70948.1 - 0.012 15.0 0.3 5.6 6.2 0.0 3.1 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Peptidase_S9_N PF02897.15 KIY70948.1 - 0.15 10.9 0.0 0.48 9.2 0.0 1.8 2 0 0 2 2 2 0 Prolyl oligopeptidase, N-terminal beta-propeller domain Ge1_WD40 PF16529.5 KIY70948.1 - 0.15 11.0 0.0 1.1 8.2 0.0 2.1 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein ABC_membrane PF00664.23 KIY70949.1 - 1.3e-49 169.4 30.6 2.1e-28 99.8 13.9 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KIY70949.1 - 1.9e-43 148.3 0.0 8e-23 81.5 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KIY70949.1 - 1.5e-07 31.1 0.4 0.0046 16.4 0.1 3.9 3 1 1 4 4 4 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KIY70949.1 - 1.9e-06 27.9 0.9 0.02 15.0 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.6 KIY70949.1 - 3e-06 27.3 4.8 0.29 10.9 0.1 3.8 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KIY70949.1 - 8.7e-05 22.2 0.8 0.47 10.2 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KIY70949.1 - 0.00086 19.3 0.3 1.6 8.6 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_25 PF13481.6 KIY70949.1 - 0.0015 18.1 0.1 0.19 11.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KIY70949.1 - 0.0038 17.6 1.2 3.2 8.1 0.0 2.9 2 1 0 2 2 2 2 AAA ATPase domain Dynamin_N PF00350.23 KIY70949.1 - 0.0047 17.0 3.3 0.54 10.3 0.3 2.7 2 0 0 2 2 2 2 Dynamin family AAA_23 PF13476.6 KIY70949.1 - 0.022 15.3 0.0 2.5 8.6 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KIY70949.1 - 0.037 13.8 1.6 27 4.4 0.0 3.3 3 0 0 3 3 3 0 AAA domain DUF815 PF05673.13 KIY70949.1 - 0.045 12.9 1.3 1.1 8.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Roc PF08477.13 KIY70949.1 - 0.073 13.3 0.2 6.7 7.0 0.1 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NB-ARC PF00931.22 KIY70949.1 - 0.16 11.2 0.2 3.3 6.8 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain Zeta_toxin PF06414.12 KIY70949.1 - 0.19 11.0 0.2 11 5.2 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin cobW PF02492.19 KIY70949.1 - 0.24 11.0 1.2 13 5.3 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 KIY70949.1 - 0.28 11.4 2.1 30 4.9 0.0 3.0 3 0 0 3 3 3 0 AAA domain TrwB_AAD_bind PF10412.9 KIY70949.1 - 0.35 9.7 1.5 7.8 5.3 0.1 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain FtsK_SpoIIIE PF01580.18 KIY70949.1 - 0.48 9.7 1.7 22 4.3 0.2 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF87 PF01935.17 KIY70949.1 - 0.86 9.6 2.3 1.8 8.6 0.2 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain WGG PF10273.9 KIY70950.1 - 7.1e-29 100.3 0.2 7.1e-29 100.3 0.2 1.7 2 0 0 2 2 2 1 Pre-rRNA-processing protein TSR2 HEPN_AbiU2 PF18734.1 KIY70950.1 - 0.014 15.0 0.0 0.016 14.7 0.0 1.2 1 0 0 1 1 1 0 AbiU2 CAF20 PF17052.5 KIY70950.1 - 0.13 12.4 1.1 0.38 10.9 1.1 1.8 1 1 0 1 1 1 0 Cap associated factor Med17 PF10156.9 KIY70950.1 - 0.16 10.7 0.9 0.16 10.6 0.9 1.1 1 0 0 1 1 1 0 Subunit 17 of Mediator complex RRP7 PF12923.7 KIY70950.1 - 0.17 12.0 0.2 0.17 12.0 0.2 2.5 1 1 1 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain F-box-like PF12937.7 KIY70951.1 - 9.2e-10 38.3 0.1 2.2e-09 37.0 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY70951.1 - 0.00081 19.2 1.5 0.024 14.5 1.5 2.7 1 1 0 1 1 1 1 F-box domain Lustrin_cystein PF14625.6 KIY70951.1 - 0.079 13.3 5.0 0.076 13.4 1.1 2.3 2 0 0 2 2 2 0 Lustrin, cysteine-rich repeated domain ADH_N PF08240.12 KIY70953.1 - 2.4e-29 101.4 0.8 4e-29 100.7 0.8 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KIY70953.1 - 6.4e-27 94.1 0.8 1.1e-26 93.3 0.8 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KIY70953.1 - 0.00021 22.3 0.2 0.00045 21.3 0.2 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 KIY70953.1 - 0.019 14.4 0.8 0.2 11.1 0.1 2.2 2 0 0 2 2 2 0 short chain dehydrogenase SfLAP PF11139.8 KIY70953.1 - 0.11 11.9 0.6 0.28 10.6 0.6 1.6 1 1 0 1 1 1 0 Sap, sulfolipid-1-addressing protein NRDE-2 PF08424.10 KIY70954.1 - 4.1e-58 197.0 5.7 4.1e-58 197.0 5.7 2.2 2 0 0 2 2 2 1 NRDE-2, necessary for RNA interference Rhamno_transf PF11316.8 KIY70954.1 - 0.61 9.4 3.7 2.5 7.4 1.4 2.3 2 0 0 2 2 2 0 Putative rhamnosyl transferase Draxin PF15550.6 KIY70954.1 - 0.72 9.7 7.7 1.5 8.6 7.7 1.4 1 0 0 1 1 1 0 Draxin TPR_14 PF13428.6 KIY70954.1 - 1.1 10.2 28.1 1.2 10.1 0.1 7.4 8 1 1 9 9 9 0 Tetratricopeptide repeat TPR_16 PF13432.6 KIY70954.1 - 3.5 8.3 15.9 0.4 11.4 1.4 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat UPF0113_N PF17833.1 KIY70955.1 - 5.9e-31 106.9 0.0 9.6e-31 106.2 0.0 1.3 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 KIY70955.1 - 5.4e-27 93.9 0.0 9.8e-27 93.0 0.0 1.4 1 0 0 1 1 1 1 UPF0113 PUA domain HpuA PF16960.5 KIY70955.1 - 0.019 14.2 0.0 0.021 14.0 0.0 1.1 1 0 0 1 1 1 0 Haemoglobin-haptoglobin utilisation, porphyrin transporter PP1 PF07430.11 KIY70955.1 - 0.13 12.4 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Phloem filament protein PP1 cystatin-like domain ADH_N PF08240.12 KIY70956.1 - 2.7e-29 101.2 0.8 4.7e-29 100.5 0.8 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KIY70956.1 - 8.9e-27 93.6 0.7 1.5e-26 92.9 0.7 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KIY70956.1 - 0.00018 22.5 0.2 0.0004 21.5 0.2 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 KIY70956.1 - 0.025 14.0 1.6 0.18 11.3 0.2 2.2 2 0 0 2 2 2 0 short chain dehydrogenase SfLAP PF11139.8 KIY70956.1 - 0.076 12.4 0.4 0.22 10.9 0.4 1.7 1 1 0 1 1 1 0 Sap, sulfolipid-1-addressing protein Syntaxin_2 PF14523.6 KIY70957.1 - 0.051 14.0 1.2 0.099 13.0 0.3 1.9 2 0 0 2 2 2 0 Syntaxin-like protein PKS_DE PF18369.1 KIY70957.1 - 0.19 12.3 0.3 0.66 10.6 0.3 2.0 1 0 0 1 1 1 0 Polyketide synthase dimerisation element domain F-box-like PF12937.7 KIY70958.1 - 1.8e-07 30.9 0.1 6.3e-07 29.2 0.1 2.0 1 1 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KIY70958.1 - 0.0031 17.9 3.1 1.6 9.3 0.2 5.0 3 1 0 4 4 4 1 Leucine Rich repeats (2 copies) F-box PF00646.33 KIY70958.1 - 0.015 15.2 0.2 0.015 15.2 0.2 2.2 2 1 0 2 2 2 0 F-box domain XPG_N PF00752.17 KIY70958.1 - 0.042 14.3 0.0 0.086 13.3 0.0 1.5 1 0 0 1 1 1 0 XPG N-terminal domain F-box-like PF12937.7 KIY70959.1 - 4.3e-07 29.7 0.5 1.6e-06 27.9 0.0 2.3 2 1 0 2 2 2 1 F-box-like F-box PF00646.33 KIY70959.1 - 0.11 12.4 0.0 0.59 10.1 0.0 2.3 1 1 0 1 1 1 0 F-box domain F-box-like PF12937.7 KIY70960.1 - 6.3e-06 26.0 0.1 1.3e-05 25.0 0.1 1.5 1 0 0 1 1 1 1 F-box-like Oxidored_FMN PF00724.20 KIY70962.1 - 5.1e-94 315.3 0.0 5.9e-94 315.1 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family MBOAT_2 PF13813.6 KIY70964.1 - 8.5e-13 48.4 5.0 8.5e-13 48.4 5.0 1.9 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family BBP1_C PF15272.6 KIY70965.1 - 0.36 10.6 3.6 0.65 9.8 3.6 1.3 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal DUF4407 PF14362.6 KIY70965.1 - 2.4 7.5 7.2 3.9 6.7 7.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DivIVA PF05103.13 KIY70965.1 - 4.3 7.4 8.3 12 6.0 8.3 1.7 1 0 0 1 1 1 0 DivIVA protein WD40 PF00400.32 KIY70966.1 - 8.6e-18 64.4 11.5 0.002 18.9 0.1 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY70966.1 - 2.6e-06 27.7 3.2 0.00076 19.7 0.5 4.0 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIY70966.1 - 1.1e-05 24.6 0.5 0.049 12.6 0.1 4.2 3 2 2 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PPR_2 PF13041.6 KIY70968.1 - 1.4e-29 102.0 0.1 1e-10 41.6 0.0 7.9 7 2 2 9 9 9 4 PPR repeat family PPR PF01535.20 KIY70968.1 - 4.2e-21 73.7 0.0 0.00015 21.8 0.0 8.7 9 0 0 9 9 9 4 PPR repeat PPR_3 PF13812.6 KIY70968.1 - 1.5e-20 73.0 0.0 3.7e-08 33.3 0.0 5.0 3 2 2 5 5 5 3 Pentatricopeptide repeat domain PPR_1 PF12854.7 KIY70968.1 - 1.3e-12 47.2 0.0 0.019 14.7 0.0 6.1 6 0 0 6 6 6 3 PPR repeat PPR_long PF17177.4 KIY70968.1 - 4.6e-12 45.8 0.1 0.0003 20.2 0.0 3.8 4 0 0 4 4 4 3 Pentacotripeptide-repeat region of PRORP TPR_19 PF14559.6 KIY70968.1 - 0.0023 18.4 1.5 0.12 12.9 1.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KIY70968.1 - 0.0053 17.5 5.2 1.4 9.9 0.5 4.4 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 KIY70968.1 - 0.0072 16.9 1.7 0.72 10.5 0.4 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat Snf7 PF03357.21 KIY70969.1 - 6.5e-29 100.7 14.2 7.8e-29 100.5 14.2 1.0 1 0 0 1 1 1 1 Snf7 DUF2524 PF10732.9 KIY70971.1 - 0.014 15.7 0.3 0.017 15.4 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2524) Sugar_tr PF00083.24 KIY70972.1 - 1.1e-109 367.4 9.4 1.3e-109 367.1 9.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY70972.1 - 1.4e-31 109.8 37.6 1.7e-26 93.0 19.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ThiD2 PF17792.1 KIY70972.1 - 0.077 13.5 0.0 0.12 12.9 0.0 1.2 1 0 0 1 1 1 0 ThiD2 family DUF1156 PF06634.12 KIY70972.1 - 0.078 13.1 0.9 0.49 10.5 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1156) SPC25 PF06703.11 KIY70972.1 - 0.74 9.6 2.1 1.9 8.3 2.1 1.6 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Peptidase_M49 PF03571.15 KIY70973.1 - 2.5e-221 735.9 0.0 3e-221 735.6 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 2C_adapt PF08793.10 KIY70973.1 - 0.085 13.1 0.1 0.18 12.0 0.1 1.5 1 0 0 1 1 1 0 2-cysteine adaptor domain LRR_4 PF12799.7 KIY70974.1 - 0.031 14.7 2.9 18 5.9 0.0 4.1 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) YozE_SAM_like PF06855.12 KIY70974.1 - 0.04 14.1 0.1 0.11 12.7 0.1 1.7 1 0 0 1 1 1 0 YozE SAM-like fold F-box-like PF12937.7 KIY70975.1 - 3e-10 39.8 0.5 5.1e-10 39.1 0.5 1.4 1 0 0 1 1 1 1 F-box-like CDC37_M PF08565.11 KIY70975.1 - 0.0099 15.8 0.0 0.013 15.4 0.0 1.1 1 0 0 1 1 1 1 Cdc37 Hsp90 binding domain F-box PF00646.33 KIY70975.1 - 0.022 14.6 1.3 0.12 12.2 1.3 2.1 1 1 0 1 1 1 0 F-box domain DHC PF09626.10 KIY70975.1 - 0.091 13.6 0.0 0.14 13.1 0.0 1.3 1 0 0 1 1 1 0 Dihaem cytochrome c Peptidase_M36 PF02128.15 KIY70976.1 - 2.4e-133 444.9 3.2 3.3e-133 444.4 3.2 1.2 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) Peptidase_M4_C PF02868.15 KIY70976.1 - 0.005 16.7 0.2 0.012 15.5 0.2 1.6 1 0 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain HHH_2 PF12826.7 KIY70976.1 - 0.037 14.1 0.2 0.21 11.7 0.0 2.1 2 0 0 2 2 2 0 Helix-hairpin-helix motif PepSY PF03413.19 KIY70976.1 - 0.042 14.4 0.2 0.089 13.4 0.2 1.6 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain Ribosomal_60s PF00428.19 KIY70976.1 - 2.9 8.5 8.5 19 6.0 8.5 2.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein MeMO_Hyd_G PF02964.16 KIY70977.1 - 0.012 15.6 0.0 0.02 14.9 0.0 1.3 1 0 0 1 1 1 0 Methane monooxygenase, hydrolase gamma chain Fungal_trans PF04082.18 KIY70978.1 - 1.4e-28 99.7 0.1 2.6e-28 98.8 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY70978.1 - 9.9e-10 38.4 8.3 1.5e-09 37.8 8.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugarporin_N PF11471.8 KIY70978.1 - 0.58 10.1 2.2 0.79 9.7 0.0 2.2 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension Gly_transf_sug PF04488.15 KIY70979.1 - 9.1e-06 26.2 0.0 3e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 KIY70979.1 - 0.035 13.5 0.3 0.054 12.9 0.3 1.2 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein PK PF00224.21 KIY70980.1 - 1.7e-164 546.8 0.9 2.2e-164 546.4 0.9 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 KIY70980.1 - 8.5e-32 109.8 0.0 2.3e-31 108.5 0.0 1.8 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 KIY70980.1 - 0.0004 19.6 0.8 0.0012 18.0 0.9 1.8 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.25 KIY70980.1 - 0.0049 15.9 0.0 0.039 13.0 0.0 2.0 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain RVT_1 PF00078.27 KIY70981.1 - 1.4e-09 37.8 0.0 4.4e-09 36.2 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) CtsR_C PF17727.1 KIY70981.1 - 0.14 12.3 0.6 0.38 10.9 0.6 1.6 1 0 0 1 1 1 0 CtsR C-terminal dimerization domain Mito_carr PF00153.27 KIY70982.1 - 7.4e-59 195.7 1.1 6.4e-20 70.9 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Colicin_V PF02674.16 KIY70982.1 - 9.7 6.1 7.1 13 5.7 0.2 3.0 3 0 0 3 3 3 0 Colicin V production protein AAA_28 PF13521.6 KIY70983.1 - 4.2e-23 82.4 0.2 5e-23 82.1 0.2 1.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KIY70983.1 - 0.0003 21.2 0.0 0.00042 20.8 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain dNK PF01712.19 KIY70983.1 - 0.00045 20.1 0.0 0.00058 19.8 0.0 1.2 1 0 0 1 1 1 1 Deoxynucleoside kinase AAA_22 PF13401.6 KIY70983.1 - 0.00061 20.1 0.1 0.0015 18.8 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KIY70983.1 - 0.0015 18.7 0.1 0.0035 17.5 0.1 1.9 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KIY70983.1 - 0.0015 18.5 0.0 0.0019 18.2 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_18 PF13238.6 KIY70983.1 - 0.0021 18.6 0.0 0.0037 17.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KIY70983.1 - 0.0031 17.3 0.0 0.0037 17.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 KIY70983.1 - 0.0055 16.1 0.0 0.21 11.0 0.0 2.2 2 0 0 2 2 2 1 Bacterial TniB protein AAA_2 PF07724.14 KIY70983.1 - 0.0072 16.5 0.0 0.01 15.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.22 KIY70983.1 - 0.009 16.4 0.0 0.019 15.3 0.0 1.6 1 1 0 1 1 1 1 RNA helicase ABC_tran PF00005.27 KIY70983.1 - 0.0094 16.5 0.0 0.013 16.0 0.0 1.5 1 1 0 1 1 1 1 ABC transporter PduV-EutP PF10662.9 KIY70983.1 - 0.01 15.6 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.15 KIY70983.1 - 0.027 14.4 0.0 0.038 13.9 0.0 1.3 1 0 0 1 1 1 0 NTPase AAA PF00004.29 KIY70983.1 - 0.029 14.8 0.0 0.068 13.6 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATP_bind_1 PF03029.17 KIY70983.1 - 0.045 13.5 0.0 0.089 12.6 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Roc PF08477.13 KIY70983.1 - 0.047 13.9 0.0 0.075 13.2 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 KIY70983.1 - 0.052 13.3 0.0 0.091 12.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Cytidylate_kin PF02224.18 KIY70983.1 - 0.056 13.2 0.0 0.073 12.8 0.0 1.5 1 1 0 1 1 1 0 Cytidylate kinase SRPRB PF09439.10 KIY70983.1 - 0.079 12.4 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Mg_chelatase PF01078.21 KIY70983.1 - 0.082 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI MMR_HSR1 PF01926.23 KIY70983.1 - 0.1 12.7 0.0 0.12 12.4 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase SRP54 PF00448.22 KIY70983.1 - 0.12 12.0 0.0 0.33 10.5 0.0 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain GTP_EFTU PF00009.27 KIY70983.1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.5 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain RdRP PF05183.12 KIY70984.1 - 1.9e-96 324.1 0.0 2.5e-96 323.6 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase nos_propeller PF18764.1 KIY70984.1 - 0.16 11.9 0.2 2.2 8.2 0.0 2.6 3 0 0 3 3 3 0 Nitrous oxide reductase propeller repeat AAA_12 PF13087.6 KIY70985.1 - 1.4e-28 99.9 0.0 1.7e-28 99.6 0.0 1.1 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 KIY70985.1 - 0.0028 17.5 0.0 0.0065 16.3 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain DUF4203 PF13886.6 KIY70986.1 - 5.4e-55 186.2 27.7 7.4e-55 185.7 27.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) Mucin PF01456.17 KIY70986.1 - 0.3 11.1 14.4 0.72 9.8 14.4 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein DEAD PF00270.29 KIY70987.1 - 9.3e-20 71.1 0.3 1.4e-19 70.5 0.3 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIY70987.1 - 2.7e-06 27.7 0.0 1.4e-05 25.4 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 KIY70987.1 - 0.00065 18.5 0.0 0.001 17.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain MOR2-PAG1_mid PF14228.6 KIY70987.1 - 0.011 13.5 0.0 0.015 13.0 0.0 1.1 1 0 0 1 1 1 0 Cell morphogenesis central region Zwilch PF09817.9 KIY70988.1 - 0.094 11.1 0.0 0.11 10.9 0.0 1.0 1 0 0 1 1 1 0 RZZ complex, subunit zwilch Abhydrolase_1 PF00561.20 KIY70989.1 - 9.3e-06 25.5 0.0 9.3e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIY70989.1 - 1.1e-05 26.2 0.1 1.2e-05 26.0 0.1 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 KIY70989.1 - 0.00057 19.7 0.0 0.00058 19.6 0.0 1.1 1 0 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.8 KIY70989.1 - 0.0011 18.2 0.0 0.0012 18.2 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KIY70989.1 - 0.0095 16.1 0.0 0.011 15.9 0.0 1.1 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_3 PF07859.13 KIY70989.1 - 0.012 15.5 0.0 0.012 15.5 0.0 1.1 1 0 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.20 KIY70989.1 - 0.074 12.7 0.0 0.074 12.7 0.0 1.1 1 0 0 1 1 1 0 Putative esterase CoA_binding PF02629.19 KIY70990.1 - 6.7e-26 90.8 0.6 1.4e-25 89.8 0.1 1.8 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 KIY70990.1 - 5.1e-24 84.8 0.1 8.8e-24 84.1 0.1 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 KIY70990.1 - 4.7e-10 39.4 0.0 1.3e-09 37.9 0.0 1.8 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 KIY70990.1 - 1e-05 26.0 0.0 2.6e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 CoA binding domain GFO_IDH_MocA PF01408.22 KIY70990.1 - 0.017 15.9 0.1 0.051 14.4 0.0 1.9 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Ribosomal_S16 PF00886.19 KIY70991.1 - 1.4e-21 76.3 0.0 1.7e-21 76.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S16 Cutinase PF01083.22 KIY70994.1 - 6.5e-28 97.9 0.2 7.9e-28 97.6 0.2 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 KIY70994.1 - 0.0033 17.0 0.0 0.0044 16.6 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_2 PF02230.16 KIY70994.1 - 0.19 11.5 0.2 0.78 9.5 0.1 1.8 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase LSM PF01423.22 KIY70995.1 - 1.4e-19 69.5 0.1 1.6e-19 69.4 0.1 1.0 1 0 0 1 1 1 1 LSM domain Mlf1IP PF10248.9 KIY70995.1 - 0.23 11.4 0.0 0.31 11.0 0.0 1.1 1 0 0 1 1 1 0 Myelodysplasia-myeloid leukemia factor 1-interacting protein Peptidase_M14 PF00246.24 KIY70996.1 - 2e-52 178.8 0.1 1.3e-51 176.1 0.1 1.9 1 1 0 1 1 1 1 Zinc carboxypeptidase Heme_oxygenase PF01126.20 KIY70996.1 - 0.14 11.9 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 Heme oxygenase DNA_pol_phi PF04931.13 KIY70996.1 - 0.43 8.6 11.2 0.53 8.3 11.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi SDA1 PF05285.12 KIY70996.1 - 1.3 8.4 14.8 1.8 7.9 14.8 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 KIY70996.1 - 2.8 6.2 4.5 3.6 5.8 4.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 KIY70996.1 - 2.8 6.1 6.4 3.7 5.6 6.4 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 KIY70996.1 - 5.3 6.3 8.8 7.7 5.7 8.8 1.1 1 0 0 1 1 1 0 BUD22 ACBP PF00887.19 KIY70997.1 - 4.4e-18 65.3 0.2 8e-18 64.4 0.2 1.4 1 0 0 1 1 1 1 Acyl CoA binding protein Ank_4 PF13637.6 KIY70997.1 - 5.7e-14 52.3 0.0 3.7e-09 36.9 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KIY70997.1 - 4.8e-12 46.3 0.0 9.2e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KIY70997.1 - 6.2e-11 41.5 0.0 1.4e-05 25.1 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 KIY70997.1 - 3.7e-09 36.7 0.0 7.4e-08 32.5 0.0 2.5 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 KIY70997.1 - 4.4e-09 36.4 0.0 5.8e-07 29.7 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat DUF1843 PF08898.10 KIY70997.1 - 0.016 15.7 0.1 1.1 9.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) FAD_binding_4 PF01565.23 KIY71000.1 - 5.9e-31 107.1 1.7 9.5e-31 106.4 1.7 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KIY71000.1 - 0.008 16.3 0.8 0.062 13.4 0.0 2.7 3 0 0 3 3 3 1 Berberine and berberine like Nop14 PF04147.12 KIY71000.1 - 3 5.9 24.9 4.5 5.4 24.9 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 KIY71000.1 - 4.6 5.4 13.1 7.7 4.7 13.1 1.3 1 0 0 1 1 1 0 CDC45-like protein Abhydrolase_3 PF07859.13 KIY71001.1 - 7.9e-23 81.4 0.0 9.2e-19 68.1 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KIY71001.1 - 2.2e-11 43.3 0.0 3.2e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Hydrolase_4 PF12146.8 KIY71001.1 - 0.00028 20.2 0.0 0.00059 19.2 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Xpo1 PF08389.12 KIY71002.1 - 1.2e-23 83.8 0.0 1.1e-21 77.4 0.0 3.1 3 0 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.19 KIY71002.1 - 2.2e-06 27.5 0.3 0.00069 19.5 0.7 3.4 2 1 1 3 3 3 2 Importin-beta N-terminal domain GATase_4 PF13230.6 KIY71003.1 - 4.9e-21 74.8 0.0 1.6e-20 73.2 0.0 1.7 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.6 KIY71003.1 - 1.1e-09 38.6 0.0 2e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DHquinase_II PF01220.19 KIY71004.1 - 8.5e-61 203.6 0.0 9.6e-61 203.5 0.0 1.0 1 0 0 1 1 1 1 Dehydroquinase class II ABA_GPCR PF12430.8 KIY71005.1 - 5.4e-35 120.8 2.1 5.4e-35 120.8 2.1 2.4 2 1 1 3 3 3 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 KIY71005.1 - 9.6e-12 44.8 0.0 2e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 The Golgi pH Regulator (GPHR) Family N-terminal DUF3085 PF11284.8 KIY71005.1 - 0.0062 16.8 0.0 0.014 15.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3085) GWT1 PF06423.12 KIY71005.1 - 0.12 12.4 3.1 1.9 8.6 0.2 2.7 2 1 1 3 3 3 0 GWT1 WD40 PF00400.32 KIY71006.1 - 2.1e-10 41.0 0.0 0.0004 21.1 0.0 2.7 2 0 0 2 2 2 2 WD domain, G-beta repeat Tim17 PF02466.19 KIY71007.1 - 0.0034 17.7 6.5 0.018 15.4 6.1 2.0 1 1 1 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family Gly-zipper_Omp PF13488.6 KIY71007.1 - 0.021 14.8 2.1 0.021 14.8 2.1 2.8 2 1 0 2 2 2 0 Glycine zipper BRCT_2 PF16589.5 KIY71008.1 - 8.3e-19 67.8 0.0 6.5e-08 32.9 0.0 2.4 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KIY71008.1 - 1.8e-06 28.3 0.2 0.0014 19.0 0.0 3.0 2 1 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain Myb_DNA-bind_2 PF08914.11 KIY71008.1 - 0.074 13.2 0.3 0.17 12.1 0.3 1.6 1 0 0 1 1 1 0 Rap1 Myb domain BRCT_2 PF16589.5 KIY71009.1 - 1.4e-16 60.6 0.0 1.3e-10 41.5 0.0 2.4 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KIY71009.1 - 6e-06 26.6 0.0 0.029 14.8 0.0 2.9 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain Haem_degrading PF03928.14 KIY71010.1 - 1.3e-27 96.2 0.0 1.6e-27 95.9 0.0 1.1 1 0 0 1 1 1 1 Haem-degrading Cutinase PF01083.22 KIY71011.1 - 1e-24 87.4 0.5 1.3e-24 87.1 0.5 1.0 1 0 0 1 1 1 1 Cutinase 2-Hacid_dh_C PF02826.19 KIY71012.1 - 8.7e-51 171.8 0.0 1.5e-50 171.0 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KIY71012.1 - 7e-35 119.6 0.0 9.2e-35 119.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KIY71012.1 - 0.0073 16.5 0.0 0.02 15.0 0.0 1.8 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 KIY71012.1 - 0.0073 16.4 0.0 0.014 15.5 0.0 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ACT PF01842.25 KIY71012.1 - 0.022 14.5 0.0 0.062 13.1 0.0 1.8 1 0 0 1 1 1 0 ACT domain F-box-like PF12937.7 KIY71013.1 - 9.8e-10 38.2 1.5 9.8e-10 38.2 1.5 1.8 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 KIY71013.1 - 0.065 13.7 5.3 15 6.1 0.0 5.0 4 2 1 5 5 5 0 Leucine Rich repeats (2 copies) Ribosomal_L4 PF00573.22 KIY71014.1 - 1.6e-60 204.1 0.0 2e-60 203.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Haem_oxygenas_2 PF14518.6 KIY71014.1 - 0.054 13.3 0.0 0.066 13.0 0.0 1.3 1 0 0 1 1 1 0 Iron-containing redox enzyme Ribosomal_S9 PF00380.19 KIY71015.1 - 4.9e-32 111.0 0.5 5.6e-32 110.8 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 BRCT_2 PF16589.5 KIY71016.1 - 8.3e-07 29.3 0.0 0.00022 21.6 0.0 2.4 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KIY71016.1 - 0.019 15.3 0.0 0.17 12.3 0.0 2.2 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain FA_desaturase PF00487.24 KIY71017.1 - 1.3e-26 94.0 21.7 2.2e-26 93.3 21.7 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 KIY71017.1 - 7.3e-09 35.7 0.0 1.8e-08 34.4 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF3821 PF12863.7 KIY71017.1 - 0.04 13.8 0.0 0.072 13.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3821) Pal1 PF08316.11 KIY71018.1 - 3.6e-15 56.9 0.5 3.6e-15 56.9 0.5 2.0 2 1 0 2 2 2 1 Pal1 cell morphology protein His_biosynth PF00977.21 KIY71019.1 - 1.6e-44 152.1 0.3 6.6e-44 150.1 0.3 2.0 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.28 KIY71019.1 - 1.6e-15 57.4 0.0 2.5e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 KIY71019.1 - 2.6e-06 27.2 0.0 5.7e-06 26.1 0.0 1.6 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain SNO PF01174.19 KIY71019.1 - 5.1e-05 23.2 0.0 0.0027 17.6 0.0 2.4 2 0 0 2 2 2 1 SNO glutamine amidotransferase family Peptidase_C26 PF07722.13 KIY71019.1 - 0.052 13.3 0.0 7.5 6.2 0.0 2.8 3 0 0 3 3 3 0 Peptidase C26 Peptidase_S51 PF03575.17 KIY71019.1 - 0.14 11.8 0.0 0.49 10.0 0.0 1.8 2 0 0 2 2 2 0 Peptidase family S51 FAD_binding_8 PF08022.12 KIY71020.1 - 9.9e-22 77.1 0.0 2e-21 76.1 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 KIY71020.1 - 2.7e-21 76.3 0.0 6.2e-21 75.1 0.0 1.6 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 KIY71020.1 - 8e-19 68.0 11.7 8e-19 68.0 11.7 2.3 1 1 1 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.21 KIY71020.1 - 0.014 16.0 0.0 0.2 12.3 0.0 2.2 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain His_Phos_2 PF00328.22 KIY71023.1 - 9.3e-35 120.7 0.0 1e-34 120.5 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) GATA PF00320.27 KIY71024.1 - 4.7e-14 51.7 7.0 5.1e-14 51.6 5.6 1.8 2 0 0 2 2 2 1 GATA zinc finger PAS PF00989.25 KIY71024.1 - 1.4e-07 31.5 0.0 3e-07 30.4 0.0 1.6 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 KIY71024.1 - 1.6e-05 25.0 0.0 5.8e-05 23.3 0.0 1.8 2 0 0 2 2 2 1 PAS domain PAS_3 PF08447.12 KIY71024.1 - 0.00049 20.3 0.0 0.0009 19.5 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 KIY71024.1 - 0.0035 17.6 0.0 0.0071 16.6 0.0 1.5 1 0 0 1 1 1 1 PAS fold F-box-like PF12937.7 KIY71025.1 - 9e-05 22.3 0.5 0.0002 21.2 0.5 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY71025.1 - 0.023 14.6 0.7 0.083 12.8 0.7 2.0 1 0 0 1 1 1 0 F-box domain LRR_2 PF07723.13 KIY71025.1 - 0.6 10.9 0.0 0.6 10.9 0.0 3.7 4 0 0 4 4 4 0 Leucine Rich Repeat Acyl-CoA_dh_1 PF00441.24 KIY71026.1 - 7.3e-42 143.1 1.2 1.7e-41 141.9 0.6 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KIY71026.1 - 4.8e-33 114.2 0.0 9.8e-33 113.2 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KIY71026.1 - 5.5e-25 87.4 0.0 1.1e-24 86.4 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KIY71026.1 - 9.4e-18 64.8 0.1 1.2e-16 61.2 0.1 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 KIY71026.1 - 0.021 14.5 0.3 0.1 12.3 0.3 1.9 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Zn_clus PF00172.18 KIY71027.1 - 1.9e-09 37.5 14.7 3e-09 36.8 14.7 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.32 KIY71030.1 - 1.2e-12 48.1 14.4 0.013 16.3 0.1 6.6 5 2 2 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY71030.1 - 4.7e-09 36.4 0.0 0.00063 20.0 0.0 3.6 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain DPPIV_N PF00930.21 KIY71030.1 - 0.0018 17.1 2.7 0.056 12.2 0.2 2.9 2 1 1 3 3 3 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region eIF2A PF08662.11 KIY71030.1 - 0.0025 17.7 0.3 0.34 10.7 0.0 3.5 4 1 0 4 4 4 1 Eukaryotic translation initiation factor eIF2A DUF5114 PF17141.4 KIY71030.1 - 0.062 13.8 0.0 0.15 12.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5114) DASH_Dad3 PF08656.10 KIY71031.1 - 5.6e-20 71.2 0.3 4.3e-19 68.4 0.3 1.9 2 0 0 2 2 2 1 DASH complex subunit Dad3 Ins_P5_2-kin PF06090.12 KIY71032.1 - 1.1e-81 274.9 0.0 1.4e-81 274.5 0.0 1.0 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase DUF1759 PF03564.15 KIY71032.1 - 0.12 12.3 0.1 0.31 11.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) BRCT_2 PF16589.5 KIY71033.1 - 1.4e-05 25.4 0.0 3.5e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Myb_DNA-bind_2 PF08914.11 KIY71033.1 - 0.00019 21.5 1.5 0.00059 20.0 1.5 1.9 1 1 0 1 1 1 1 Rap1 Myb domain Rap1-DNA-bind PF09197.10 KIY71033.1 - 4.4 8.0 7.6 0.31 11.6 0.5 2.7 2 0 0 2 2 2 0 Rap1, DNA-binding DUF4578 PF15147.6 KIY71033.1 - 6.4 7.7 7.4 0.95 10.4 2.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4578) MMM1 PF10296.9 KIY71035.1 - 1.3e-14 54.0 0.3 1.1e-10 41.1 0.1 2.2 2 0 0 2 2 2 2 Maintenance of mitochondrial morphology protein 1 KIF1B PF12423.8 KIY71035.1 - 0.16 12.4 2.8 0.38 11.2 2.8 1.6 1 0 0 1 1 1 0 Kinesin protein 1B Ku PF02735.16 KIY71036.1 - 1.7e-32 112.8 0.0 4.1e-32 111.5 0.0 1.6 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 KIY71036.1 - 1.2e-19 70.9 0.0 2e-19 70.2 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 KIY71036.1 - 4.7e-18 65.7 0.2 1.5e-17 64.1 0.2 1.9 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm SAP PF02037.27 KIY71036.1 - 1.9e-09 37.0 0.1 3.7e-09 36.1 0.1 1.5 1 0 0 1 1 1 1 SAP domain VWA_2 PF13519.6 KIY71036.1 - 0.053 14.2 0.0 0.77 10.4 0.0 2.3 2 0 0 2 2 2 0 von Willebrand factor type A domain Radical_SAM_C PF16199.5 KIY71037.1 - 1.9e-29 101.5 0.0 3.5e-29 100.6 0.0 1.5 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 KIY71037.1 - 4.9e-17 62.8 0.1 1.2e-16 61.5 0.0 1.7 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 KIY71037.1 - 8e-11 42.2 0.1 1.6e-10 41.2 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KIY71037.1 - 2.3e-06 27.5 0.0 6.1e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KIY71037.1 - 0.0022 18.4 0.1 0.011 16.2 0.0 2.2 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIY71037.1 - 0.096 12.7 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein GDA1_CD39 PF01150.17 KIY71038.1 - 1.4e-100 337.0 0.0 1.9e-100 336.5 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.16 KIY71038.1 - 0.026 14.0 0.0 0.04 13.3 0.0 1.2 1 0 0 1 1 1 0 Ppx/GppA phosphatase family ArAE_2_N PF10337.9 KIY71039.1 - 3e-61 207.9 17.0 2e-59 201.9 11.6 3.0 2 1 0 2 2 2 2 Putative ER transporter, 6TM, N-terminal ArAE_2 PF10334.9 KIY71039.1 - 2e-31 109.6 0.0 3.6e-31 108.8 0.0 1.4 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 FUSC_2 PF13515.6 KIY71039.1 - 4.7e-08 33.2 17.8 4.7e-08 33.2 17.8 3.6 2 1 0 2 2 2 1 Fusaric acid resistance protein-like TMEM237 PF15383.6 KIY71039.1 - 3.7 6.6 5.0 0.92 8.5 0.9 2.1 3 0 0 3 3 3 0 Transmembrane protein 237 DUF4537 PF15057.6 KIY71041.1 - 4.7e-05 23.4 0.0 0.00012 22.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) PWWP PF00855.17 KIY71041.1 - 0.056 13.9 0.9 1.2 9.5 0.2 2.7 2 0 0 2 2 2 0 PWWP domain DIOX_N PF14226.6 KIY71042.1 - 5e-14 53.1 0.0 7.9e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KIY71042.1 - 5.6e-13 49.2 0.3 1.3e-12 48.1 0.1 1.9 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily MutL_C PF08676.11 KIY71044.1 - 4e-26 91.5 0.0 9.1e-26 90.4 0.0 1.6 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 KIY71044.1 - 3.7e-20 71.8 0.0 7.1e-20 70.9 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 KIY71044.1 - 4.8e-14 52.4 0.5 1.4e-13 50.9 0.5 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KIY71044.1 - 4.6e-06 27.1 0.5 1.3e-05 25.6 0.1 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PI3K_1B_p101 PF10486.9 KIY71044.1 - 3.8 5.2 7.7 6.5 4.4 7.7 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit WD40 PF00400.32 KIY71046.1 - 5.5e-41 137.8 24.7 1.3e-05 25.8 0.1 7.9 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.7 KIY71046.1 - 7.6e-13 48.1 3.2 1.9e-12 46.8 3.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY71046.1 - 4.5e-09 36.0 1.2 4.5e-09 36.0 1.2 2.2 2 0 0 2 2 2 1 F-box domain ANAPC4_WD40 PF12894.7 KIY71046.1 - 3.2e-08 33.8 0.3 3.2 8.1 0.0 5.4 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIY71046.1 - 1.9e-05 23.5 7.1 0.16 10.6 0.4 5.1 3 2 1 5 5 5 2 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 KIY71046.1 - 0.12 11.3 5.4 3.3 6.5 0.1 3.3 4 1 1 5 5 5 0 Partner and localizer of BRCA2 WD40 domain Hira PF07569.11 KIY71046.1 - 4.1 7.1 5.1 61 3.2 0.0 4.3 5 1 2 7 7 7 0 TUP1-like enhancer of split Fungal_trans PF04082.18 KIY71047.1 - 4.2e-16 58.8 0.1 8.3e-16 57.8 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY71047.1 - 1.3e-05 25.2 8.2 2.3e-05 24.4 8.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PrkA PF06798.12 KIY71052.1 - 0.015 14.9 1.3 0.021 14.4 0.9 1.5 1 1 1 2 2 2 0 PrkA serine protein kinase C-terminal domain Presenilin PF01080.17 KIY71056.1 - 2.7 6.7 3.4 4.1 6.1 3.4 1.2 1 0 0 1 1 1 0 Presenilin KDZ PF18758.1 KIY71058.1 - 1.8e-46 158.6 0.0 2.9e-46 157.9 0.0 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KIY71058.1 - 4.9e-30 103.8 0.6 5.7e-29 100.4 0.5 2.3 2 0 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KIY71058.1 - 1.7e-05 24.9 0.2 5.5e-05 23.3 0.2 1.9 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases YTH PF04146.15 KIY71060.1 - 1.5e-38 132.4 0.1 3.5e-38 131.1 0.1 1.7 1 0 0 1 1 1 1 YT521-B-like domain CN_hydrolase PF00795.22 KIY71061.1 - 1.3e-33 116.4 0.0 1.7e-33 116.0 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Aminotran_1_2 PF00155.21 KIY71062.1 - 1e-33 117.1 0.0 1.3e-33 116.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II PFU PF09070.11 KIY71064.1 - 1.8e-43 147.3 0.0 4.6e-43 146.1 0.0 1.7 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) PUL PF08324.11 KIY71064.1 - 7e-39 133.7 0.1 9.3e-39 133.3 0.1 1.2 1 0 0 1 1 1 1 PUL domain WD40 PF00400.32 KIY71064.1 - 9.4e-30 102.2 14.6 1.7e-06 28.7 0.2 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat BBS2_Mid PF14783.6 KIY71064.1 - 9e-06 25.7 0.0 0.015 15.4 0.0 3.1 2 1 1 3 3 3 3 Ciliary BBSome complex subunit 2, middle region Na_Ca_ex PF01699.24 KIY71065.1 - 1.2e-36 125.9 42.5 5.4e-21 75.1 19.0 2.6 3 0 0 3 3 3 2 Sodium/calcium exchanger protein His_Phos_1 PF00300.22 KIY71066.1 - 1.7e-39 135.5 0.1 2.2e-39 135.1 0.1 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) GH131_N PF18271.1 KIY71067.1 - 2.5e-55 187.9 1.8 2.5e-55 187.9 1.8 1.9 2 1 0 2 2 2 1 Glycoside hydrolase 131 catalytic N-terminal domain DUF4012 PF13196.6 KIY71068.1 - 0.095 13.2 0.8 3.4 8.1 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4012) Atg14 PF10186.9 KIY71068.1 - 3.8 6.5 11.3 6.7 5.7 11.3 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 APG6_N PF17675.1 KIY71068.1 - 5 7.7 31.7 0.79 10.3 13.5 3.2 2 1 1 3 3 3 0 Apg6 coiled-coil region Septin PF00735.18 KIY71069.1 - 1.9e-114 381.7 0.8 2.3e-114 381.5 0.8 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KIY71069.1 - 1.9e-09 37.6 0.1 4.3e-09 36.5 0.1 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 KIY71069.1 - 3.2e-07 29.9 0.0 7e-07 28.8 0.0 1.6 2 0 0 2 2 2 1 AIG1 family RsgA_GTPase PF03193.16 KIY71069.1 - 1.5e-06 28.2 0.2 4.3e-05 23.5 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 KIY71069.1 - 1.9e-06 27.5 0.5 0.00035 20.2 0.1 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KIY71069.1 - 3.7e-05 23.8 0.6 0.078 13.0 0.2 2.4 1 1 1 2 2 2 2 Dynamin family AAA_16 PF13191.6 KIY71069.1 - 0.00015 22.2 0.0 0.00045 20.7 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.22 KIY71069.1 - 0.00041 19.6 0.0 0.00064 19.0 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain T2SSE PF00437.20 KIY71069.1 - 0.0012 18.0 0.0 0.0023 17.0 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein RuvB_N PF05496.12 KIY71069.1 - 0.0018 18.0 0.1 0.86 9.3 0.0 2.2 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain FtsK_SpoIIIE PF01580.18 KIY71069.1 - 0.0019 17.6 0.0 0.0048 16.3 0.0 1.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family ABC_tran PF00005.27 KIY71069.1 - 0.0019 18.7 0.0 0.0045 17.5 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_7 PF12775.7 KIY71069.1 - 0.0065 16.0 0.5 0.076 12.5 0.1 2.3 1 1 1 2 2 2 1 P-loop containing dynein motor region Ras PF00071.22 KIY71069.1 - 0.008 15.8 0.3 0.044 13.4 0.1 2.1 2 0 0 2 2 2 1 Ras family Roc PF08477.13 KIY71069.1 - 0.011 16.0 0.0 0.022 15.0 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 KIY71069.1 - 0.016 15.5 0.0 0.029 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KIY71069.1 - 0.037 14.1 0.5 0.28 11.2 0.1 2.4 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KIY71069.1 - 0.037 13.8 0.0 0.073 12.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Gtr1_RagA PF04670.12 KIY71069.1 - 0.054 12.8 0.2 0.48 9.7 0.0 2.1 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region IIGP PF05049.13 KIY71069.1 - 0.063 12.3 0.2 0.13 11.3 0.1 1.5 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) G-alpha PF00503.20 KIY71069.1 - 0.086 12.0 0.4 0.89 8.6 0.1 1.9 1 1 1 2 2 2 0 G-protein alpha subunit DUF815 PF05673.13 KIY71069.1 - 0.14 11.3 0.0 0.27 10.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 KIY71069.1 - 0.16 11.6 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_23 PF13476.6 KIY71069.1 - 0.33 11.4 1.3 0.57 10.6 1.3 1.7 1 1 0 1 1 1 0 AAA domain SH3_1 PF00018.28 KIY71070.1 - 4.7e-07 29.3 0.0 7.7e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KIY71070.1 - 4.8e-07 29.5 0.0 7.7e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain hSH3 PF14603.6 KIY71070.1 - 0.00082 19.8 0.0 0.0013 19.1 0.0 1.2 1 0 0 1 1 1 1 Helically-extended SH3 domain SH3_2 PF07653.17 KIY71070.1 - 0.0022 17.6 0.0 0.0043 16.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Amnionless PF14828.6 KIY71070.1 - 0.0063 15.4 0.1 0.011 14.6 0.1 1.4 1 1 0 1 1 1 1 Amnionless TMEM154 PF15102.6 KIY71070.1 - 0.063 13.2 0.0 0.063 13.2 0.0 2.3 1 1 1 2 2 1 0 TMEM154 protein family SPX PF03105.19 KIY71070.1 - 0.066 13.1 4.4 0.085 12.8 4.4 1.2 1 0 0 1 1 1 0 SPX domain DUF2207 PF09972.9 KIY71070.1 - 0.13 11.0 0.0 0.17 10.6 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Apt1 PF10351.9 KIY71070.1 - 0.15 10.9 2.4 0.16 10.8 2.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF1180 PF06679.12 KIY71070.1 - 3.2 8.1 19.4 1.1 9.7 9.9 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1180) MAP65_ASE1 PF03999.12 KIY71070.1 - 8.2 5.0 5.3 9.8 4.7 5.3 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) SRP40_C PF05022.12 KIY71071.1 - 5.3e-27 94.5 0.4 1.6e-26 92.9 0.4 1.9 1 0 0 1 1 1 1 SRP40, C-terminal domain ATP_bind_3 PF01171.20 KIY71072.1 - 5e-38 130.7 0.0 7.7e-38 130.1 0.0 1.3 1 0 0 1 1 1 1 PP-loop family T3SSipB PF16535.5 KIY71072.1 - 0.041 14.3 0.4 0.041 14.3 0.4 1.6 2 0 0 2 2 2 0 Type III cell invasion protein SipB CwfJ_C_1 PF04677.15 KIY71073.1 - 7.8e-30 103.3 0.0 1.3e-29 102.5 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 zf-CCHC_2 PF13696.6 KIY71073.1 - 3.6e-22 77.8 18.1 4e-11 42.5 0.8 3.5 3 0 0 3 3 3 3 Zinc knuckle CwfJ_C_2 PF04676.14 KIY71073.1 - 2.7e-14 53.8 0.0 5.5e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 zf-CCHC PF00098.23 KIY71073.1 - 2e-08 33.9 15.8 0.00035 20.5 0.1 4.0 4 0 0 4 4 4 3 Zinc knuckle Zn_ribbon_SprT PF17283.2 KIY71073.1 - 0.0035 17.2 2.2 2.9 7.9 0.0 3.3 3 0 0 3 3 3 1 SprT-like zinc ribbon domain UDG PF03167.19 KIY71073.1 - 0.12 12.4 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Uracil DNA glycosylase superfamily Endonuclease_7 PF02945.15 KIY71073.1 - 0.29 11.1 1.2 0.91 9.5 1.2 1.8 1 0 0 1 1 1 0 Recombination endonuclease VII zf-CCHC_6 PF15288.6 KIY71073.1 - 8.6 6.3 6.7 47 3.9 0.7 3.2 2 0 0 2 2 2 0 Zinc knuckle Lipase_3 PF01764.25 KIY71074.1 - 1.3e-28 99.7 0.0 1.8e-28 99.2 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KIY71074.1 - 5.2e-05 23.9 0.2 7.6e-05 23.4 0.2 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 KIY71074.1 - 0.001 18.8 0.1 0.0015 18.3 0.1 1.2 1 0 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.8 KIY71074.1 - 0.0057 15.9 0.1 0.0091 15.3 0.1 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KIY71074.1 - 0.012 15.3 0.0 0.018 14.7 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.20 KIY71074.1 - 0.023 14.4 0.1 0.042 13.5 0.1 1.4 1 0 0 1 1 1 0 Putative esterase PE-PPE PF08237.11 KIY71074.1 - 0.098 12.2 0.1 0.17 11.4 0.1 1.4 1 0 0 1 1 1 0 PE-PPE domain 5_nucleotid_C PF02872.18 KIY71075.1 - 8.4e-31 107.3 0.1 1.8e-30 106.2 0.1 1.5 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 KIY71075.1 - 2.7e-12 47.6 0.8 4.7e-12 46.8 0.8 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase HSP70 PF00012.20 KIY71076.1 - 6.6e-253 840.3 5.0 7.5e-253 840.1 5.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KIY71076.1 - 4.5e-19 68.4 0.8 4.4e-18 65.2 0.5 2.1 2 0 0 2 2 2 1 MreB/Mbl protein Hydantoinase_A PF01968.18 KIY71076.1 - 0.004 16.5 0.3 0.009 15.3 0.1 1.7 1 1 0 1 1 1 1 Hydantoinase/oxoprolinase FGGY_C PF02782.16 KIY71076.1 - 0.17 11.6 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Glyco_trans_2_3 PF13632.6 KIY71077.1 - 4.5e-55 186.6 0.2 4.5e-55 186.6 0.2 2.3 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KIY71077.1 - 9.5e-05 22.4 0.0 0.00019 21.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KIY71077.1 - 0.0077 16.1 0.5 0.018 14.8 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 2 CBF PF03914.17 KIY71078.1 - 2.3e-29 102.6 1.3 2.3e-29 102.6 1.3 3.1 3 1 0 3 3 3 2 CBF/Mak21 family Glyco_hydro_31 PF01055.26 KIY71079.1 - 3.1e-120 402.3 0.5 4.3e-120 401.9 0.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KIY71079.1 - 7.5e-18 64.6 0.2 2.4e-17 63.0 0.2 2.0 1 0 0 1 1 1 1 Galactose mutarotase-like Glyco_hydro_16 PF00722.21 KIY71080.1 - 1.1e-05 25.0 0.0 2.8e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DPBB_1 PF03330.18 KIY71080.1 - 0.0028 17.9 0.0 0.01 16.1 0.0 2.0 2 0 0 2 2 2 1 Lytic transglycolase UCH PF00443.29 KIY71081.1 - 2e-42 145.5 0.0 2.8e-42 145.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KIY71081.1 - 2.3e-06 27.4 0.0 0.01 15.5 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Choline_transpo PF04515.12 KIY71082.1 - 1.3e-32 113.3 7.3 1.3e-32 113.3 7.3 2.9 1 1 0 2 2 2 1 Plasma-membrane choline transporter Thaumatin PF00314.17 KIY71083.1 - 1.5e-17 63.9 1.4 1.5e-17 63.9 1.4 1.4 1 1 0 1 1 1 1 Thaumatin family DUF4135 PF13575.6 KIY71084.1 - 0.038 13.3 0.1 0.21 10.9 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4135) Methyltransf_2 PF00891.18 KIY71085.1 - 1.1e-19 70.6 0.0 5.2e-19 68.4 0.0 1.8 1 1 0 1 1 1 1 O-methyltransferase domain DOT1 PF08123.13 KIY71085.1 - 0.03 13.9 0.0 0.047 13.2 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_25 PF13649.6 KIY71085.1 - 0.12 13.1 0.0 0.27 12.0 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain RNA_pol_Rpc34 PF05158.12 KIY71085.1 - 0.13 11.6 0.0 0.2 11.0 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase Rpc34 subunit UPF1_Zn_bind PF09416.10 KIY71087.1 - 9e-45 152.4 8.8 1.3e-44 151.9 8.8 1.2 1 0 0 1 1 1 1 RNA helicase (UPF2 interacting domain) Vps36-NZF-N PF16988.5 KIY71087.1 - 0.26 10.7 3.2 7.5 6.0 1.0 2.6 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-H2C2_2 PF13465.6 KIY71087.1 - 6.6 7.4 8.4 14 6.3 0.5 3.4 2 1 1 3 3 3 0 Zinc-finger double domain Cyclin_N PF00134.23 KIY71088.1 - 3.2e-11 43.1 0.0 4.9e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 KIY71088.1 - 8.1e-07 29.5 0.1 1.4e-06 28.8 0.1 1.5 1 1 0 1 1 1 1 Cyclin SPX PF03105.19 KIY71088.1 - 3.2 7.6 5.3 42 3.9 5.3 2.0 1 1 0 1 1 1 0 SPX domain zf-C4H2 PF10146.9 KIY71089.1 - 1.1e-07 32.4 5.4 1.1e-07 32.4 5.4 1.6 2 0 0 2 2 2 1 Zinc finger-containing protein PRIMA1 PF16101.5 KIY71089.1 - 0.024 14.7 3.3 0.047 13.7 3.3 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Fez1 PF06818.15 KIY71089.1 - 0.061 13.8 9.4 0.079 13.4 9.4 1.1 1 0 0 1 1 1 0 Fez1 KASH_CCD PF14662.6 KIY71089.1 - 0.075 12.8 10.8 0.1 12.4 10.8 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH DUF3450 PF11932.8 KIY71089.1 - 0.096 12.0 8.7 0.18 11.1 8.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) HemY_N PF07219.13 KIY71089.1 - 0.11 12.8 1.3 11 6.3 0.4 2.4 2 1 0 2 2 2 0 HemY protein N-terminus DUF4972 PF16342.5 KIY71089.1 - 0.16 11.7 3.9 1.7 8.4 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4972) DUF1664 PF07889.12 KIY71089.1 - 0.26 11.3 3.4 0.39 10.8 3.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Exonuc_VII_L PF02601.15 KIY71089.1 - 0.69 9.4 5.9 0.86 9.1 5.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4239 PF14023.6 KIY71089.1 - 0.79 9.4 2.6 1.1 9.0 2.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) YlqD PF11068.8 KIY71089.1 - 2.3 8.6 10.6 1.5 9.2 6.9 2.0 1 1 1 2 2 2 0 YlqD protein TMPIT PF07851.13 KIY71089.1 - 3.2 6.9 4.3 4.4 6.4 4.3 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF2205 PF10224.9 KIY71089.1 - 3.5 7.7 10.4 1.8 8.6 5.6 2.8 1 1 0 2 2 2 0 Short coiled-coil protein FUSC PF04632.12 KIY71089.1 - 4 5.8 5.9 4.7 5.6 5.9 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Atg14 PF10186.9 KIY71089.1 - 6.4 5.8 12.1 9.1 5.3 12.1 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Acetyltransf_1 PF00583.25 KIY71090.1 - 6.7e-09 36.0 0.0 8.8e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KIY71090.1 - 2.5e-06 27.8 0.0 3.4e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KIY71090.1 - 4.4e-05 23.4 0.0 6.3e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIY71090.1 - 0.00059 19.7 0.0 0.0012 18.8 0.0 1.5 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 KIY71090.1 - 0.0007 19.8 0.0 0.00097 19.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KIY71090.1 - 0.059 13.5 0.1 0.1 12.7 0.1 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Yip1 PF04893.17 KIY71091.1 - 0.042 13.6 0.1 0.074 12.8 0.1 1.4 1 0 0 1 1 1 0 Yip1 domain Syndecan PF01034.20 KIY71091.1 - 0.062 13.2 0.2 0.13 12.2 0.2 1.5 1 0 0 1 1 1 0 Syndecan domain zf-RING_UBOX PF13445.6 KIY71092.1 - 4.1e-08 33.1 3.1 4.1e-08 33.1 3.1 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 KIY71092.1 - 5.7e-06 26.6 10.2 2.1e-05 24.7 5.7 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 KIY71092.1 - 1.4e-05 24.9 1.3 1.4e-05 24.9 1.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KIY71092.1 - 2.6e-05 24.0 5.3 2.6e-05 24.0 5.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 KIY71092.1 - 3.5e-05 23.6 0.4 7.4e-05 22.5 0.4 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.6 KIY71092.1 - 6.2e-05 22.9 8.9 0.00084 19.3 4.6 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KIY71092.1 - 0.00011 22.0 7.6 0.0012 18.6 3.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KIY71092.1 - 0.00014 22.0 4.4 0.00036 20.6 1.3 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KIY71092.1 - 0.00017 21.4 6.5 0.0013 18.5 1.5 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KIY71092.1 - 0.012 15.9 6.7 0.023 15.0 2.3 2.5 2 0 0 2 2 2 0 RING-H2 zinc finger domain DivIC PF04977.15 KIY71092.1 - 0.015 15.1 1.3 0.025 14.3 1.3 1.3 1 0 0 1 1 1 0 Septum formation initiator HALZ PF02183.18 KIY71092.1 - 0.031 14.5 0.6 0.06 13.6 0.6 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper DUF5089 PF17002.5 KIY71092.1 - 0.034 14.0 3.5 0.052 13.4 3.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5089) YojJ PF10372.9 KIY71092.1 - 0.046 13.8 0.1 0.097 12.8 0.1 1.5 1 0 0 1 1 1 0 Bacterial membrane-spanning protein N-terminus zf-ANAPC11 PF12861.7 KIY71092.1 - 0.053 13.6 6.5 1.1 9.4 3.7 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger CLZ PF16526.5 KIY71092.1 - 0.088 13.2 0.9 0.17 12.2 0.9 1.5 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4164 PF13747.6 KIY71092.1 - 0.097 13.0 0.9 0.17 12.2 0.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) DUF334 PF03904.13 KIY71092.1 - 0.14 11.7 0.5 0.18 11.3 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF334) Zn_ribbon_17 PF17120.5 KIY71092.1 - 0.25 11.0 7.8 0.044 13.4 3.3 1.9 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type FYVE PF01363.21 KIY71092.1 - 3.4 7.9 9.8 22 5.3 9.2 2.5 1 1 1 2 2 2 0 FYVE zinc finger CEBP_ZZ PF16366.5 KIY71092.1 - 4.1 7.7 8.3 2 8.7 4.6 2.1 2 0 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain LUC7 PF03194.15 KIY71092.1 - 8.5 6.0 8.0 0.7 9.5 2.6 1.7 2 0 0 2 2 2 0 LUC7 N_terminus Med12 PF09497.10 KIY71093.1 - 1.1e-25 89.6 0.0 4.6e-25 87.7 0.0 2.2 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 Med12-LCEWAV PF12145.8 KIY71093.1 - 0.002 17.1 0.1 0.12 11.2 0.0 2.2 1 1 1 2 2 2 2 Eukaryotic Mediator 12 subunit domain DNA_pol_lambd_f PF10391.9 KIY71093.1 - 0.049 13.5 0.0 0.15 11.9 0.0 1.8 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda Mito_carr PF00153.27 KIY71094.1 - 1.2e-53 179.0 6.4 6.1e-21 74.1 0.1 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF2085 PF09858.9 KIY71094.1 - 0.05 14.1 0.2 0.2 12.1 0.0 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2085) Glyco_hydro_43 PF04616.14 KIY71095.1 - 3.3e-71 240.0 0.1 5.6e-71 239.2 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KIY71095.1 - 1.4e-33 116.3 0.0 2.3e-33 115.6 0.0 1.2 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain DUF746 PF05344.11 KIY71096.1 - 0.0069 16.2 0.3 0.79 9.6 0.1 2.5 2 0 0 2 2 2 1 Domain of Unknown Function (DUF746) DUF773 PF05600.12 KIY71096.1 - 0.24 10.1 3.5 0.52 9.0 3.5 1.5 1 0 0 1 1 1 0 CDK5 regulatory subunit-associated protein 3 HAUS2 PF15003.6 KIY71096.1 - 0.66 9.7 4.6 6 6.5 1.3 2.6 3 0 0 3 3 3 0 HAUS augmin-like complex subunit 2 DUF3552 PF12072.8 KIY71096.1 - 8.5 5.7 14.4 17 4.7 14.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) GIY-YIG PF01541.24 KIY71097.1 - 1.5e-12 47.6 0.0 2.8e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 GIY-YIG catalytic domain AT_hook PF02178.19 KIY71097.1 - 0.0018 17.9 7.7 0.026 14.4 3.7 3.0 2 0 0 2 2 2 1 AT hook motif Prok-RING_1 PF14446.6 KIY71097.1 - 0.024 14.5 0.8 0.024 14.5 0.8 1.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 DZR PF12773.7 KIY71097.1 - 0.52 10.4 5.4 0.29 11.2 2.2 2.0 2 0 0 2 2 2 0 Double zinc ribbon OrfB_Zn_ribbon PF07282.11 KIY71097.1 - 0.93 9.5 2.6 1.2 9.1 0.9 2.0 2 0 0 2 2 2 0 Putative transposase DNA-binding domain PLDc_2 PF13091.6 KIY71099.1 - 4.4e-18 65.4 0.2 1.6e-07 31.3 0.0 3.4 3 0 0 3 3 3 3 PLD-like domain PLDc PF00614.22 KIY71099.1 - 1.3e-16 60.0 5.1 7.1e-09 35.5 0.7 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif Peptidase_M19 PF01244.21 KIY71101.1 - 6.4e-106 354.1 0.0 7.6e-106 353.9 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Peptidase_C12 PF01088.21 KIY71102.1 - 1.1e-52 178.9 0.0 1.5e-52 178.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 KIY71102.1 - 1.1e-11 44.4 0.0 2e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases Med31 PF05669.12 KIY71103.1 - 9.2e-36 121.7 10.6 1.1e-35 121.5 10.6 1.1 1 0 0 1 1 1 1 SOH1 TPT PF03151.16 KIY71104.1 - 1.9e-27 96.4 10.9 2.6e-27 96.0 10.9 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KIY71104.1 - 1.3e-09 38.3 29.4 2.6e-05 24.4 11.7 2.3 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 KIY71104.1 - 3.1e-05 23.3 14.5 0.0001 21.6 14.5 1.8 1 1 0 1 1 1 1 UAA transporter family PUNUT PF16913.5 KIY71104.1 - 0.008 15.4 15.6 0.013 14.7 15.6 1.3 1 0 0 1 1 1 1 Purine nucleobase transmembrane transport Zn_clus PF00172.18 KIY71105.1 - 3.6e-05 23.8 9.9 5.6e-05 23.2 9.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KIY71105.1 - 3.8e-05 22.9 0.2 5.1e-05 22.4 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain EB1_binding PF05937.11 KIY71105.1 - 0.43 11.2 5.9 0.71 10.5 5.9 1.3 1 0 0 1 1 1 0 EB-1 Binding Domain Apolipoprotein PF01442.18 KIY71106.1 - 0.011 15.6 8.3 0.019 14.8 8.3 1.4 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 KIY71106.1 - 0.15 12.7 19.4 0.049 14.2 4.1 2.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 KIY71106.1 - 0.24 12.0 18.6 1.3e+04 -3.2 18.6 2.9 1 1 0 1 1 1 0 YtxH-like protein DUF4407 PF14362.6 KIY71106.1 - 0.82 9.0 6.6 1.1 8.5 6.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Borrelia_P83 PF05262.11 KIY71106.1 - 7.3 5.0 17.6 9.6 4.6 17.6 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein G-alpha PF00503.20 KIY71108.1 - 2.6e-111 372.2 0.0 3.1e-111 372.0 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KIY71108.1 - 1.3e-08 34.5 0.0 1.4e-05 24.6 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 KIY71108.1 - 0.0062 16.7 0.0 1.8 8.8 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 KIY71108.1 - 0.022 14.5 0.0 0.07 12.9 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.27 KIY71108.1 - 0.072 12.6 0.0 1.1 8.8 0.0 2.1 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KIY71108.1 - 0.11 11.8 0.1 8 5.7 0.1 2.2 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_24 PF13479.6 KIY71108.1 - 0.12 12.1 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 KIY71108.1 - 0.16 11.4 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Fungal_trans PF04082.18 KIY71109.1 - 3e-14 52.7 0.0 5e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KIY71109.1 - 1e-06 28.8 12.7 0.00078 19.8 5.5 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KIY71109.1 - 1.2e-06 28.6 2.7 1.2e-06 28.6 2.7 2.9 3 0 0 3 3 3 1 Zinc-finger double domain Zn_clus PF00172.18 KIY71109.1 - 2.6e-06 27.5 10.1 2.6e-06 27.5 10.1 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.6 KIY71109.1 - 0.00012 22.6 12.6 0.0028 18.4 3.6 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KIY71109.1 - 0.024 14.6 6.4 0.12 12.4 0.4 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KIY71109.1 - 0.089 12.6 3.4 0.28 11.0 3.4 1.9 1 0 0 1 1 1 0 C2H2-type zinc-finger domain zf-C2H2_11 PF16622.5 KIY71109.1 - 0.14 12.0 5.0 0.32 10.8 1.3 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type F-box-like PF12937.7 KIY71111.1 - 0.011 15.6 0.0 0.031 14.2 0.0 1.8 1 0 0 1 1 1 0 F-box-like FAD_binding_2 PF00890.24 KIY71113.1 - 3.9e-90 302.9 1.6 4.9e-90 302.6 1.6 1.1 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.28 KIY71113.1 - 9.6e-23 80.1 0.0 1.7e-21 76.2 0.0 2.5 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.24 KIY71113.1 - 7.5e-13 48.8 1.3 1.8e-12 47.5 1.3 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KIY71113.1 - 7.8e-11 42.0 1.5 1.8e-10 40.8 1.5 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KIY71113.1 - 8.8e-10 38.7 0.4 5.5e-09 36.1 0.2 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KIY71113.1 - 2.9e-09 36.6 0.7 3.4e-08 33.1 0.4 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KIY71113.1 - 5.3e-07 29.2 0.3 8.1e-07 28.6 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 KIY71113.1 - 1.6e-06 27.5 1.6 0.00018 20.7 1.4 2.4 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.14 KIY71113.1 - 0.00013 20.8 6.9 0.00029 19.6 0.8 2.7 3 0 0 3 3 3 1 HI0933-like protein Pyr_redox_3 PF13738.6 KIY71113.1 - 0.00019 20.8 0.5 0.22 10.8 0.4 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KIY71113.1 - 0.0003 20.2 1.7 0.0056 16.0 0.4 2.6 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.21 KIY71113.1 - 0.00098 18.5 2.9 0.0022 17.3 0.9 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 KIY71113.1 - 0.0019 17.5 2.6 0.021 14.1 0.8 2.5 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 KIY71113.1 - 0.004 17.7 1.3 0.029 14.9 0.3 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KIY71113.1 - 0.015 14.4 0.3 0.024 13.7 0.3 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_7 PF13241.6 KIY71113.1 - 0.016 15.6 0.0 0.032 14.7 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding NAD_binding_9 PF13454.6 KIY71113.1 - 0.02 14.9 0.8 0.41 10.6 0.8 2.4 1 1 0 1 1 1 0 FAD-NAD(P)-binding 3HCDH_N PF02737.18 KIY71113.1 - 0.19 11.6 0.2 0.32 10.8 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AAA_18 PF13238.6 KIY71114.1 - 1.5e-06 28.8 0.3 8.9e-06 26.3 0.3 2.0 1 1 0 1 1 1 1 AAA domain PRK PF00485.18 KIY71114.1 - 0.0014 18.4 0.2 0.0086 15.8 0.2 2.0 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.6 KIY71114.1 - 0.0019 18.4 0.0 0.32 11.1 0.0 2.2 2 1 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 KIY71114.1 - 0.052 12.8 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_28 PF13521.6 KIY71114.1 - 0.06 13.6 0.2 0.17 12.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 KIY71114.1 - 0.13 11.3 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_2 PF07724.14 KIY71115.1 - 6.7e-47 159.8 0.0 1.2e-44 152.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 KIY71115.1 - 2.1e-33 114.4 0.7 2.1e-33 114.4 0.7 2.3 1 1 1 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 KIY71115.1 - 4e-20 71.7 0.4 1.4e-19 69.9 0.4 2.1 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 KIY71115.1 - 7.6e-20 71.7 0.2 2.1e-10 41.2 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KIY71115.1 - 6.1e-17 61.9 0.0 2.6e-11 43.7 0.0 3.2 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KIY71115.1 - 8.6e-10 39.0 1.3 0.0042 17.4 0.0 4.3 4 2 0 4 4 4 2 AAA domain AAA_16 PF13191.6 KIY71115.1 - 1.1e-09 39.0 7.7 0.0006 20.2 0.1 4.7 3 2 1 5 5 4 2 AAA ATPase domain Sigma54_activat PF00158.26 KIY71115.1 - 6.5e-08 32.5 0.0 4.7e-06 26.4 0.0 2.6 2 1 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 KIY71115.1 - 7.2e-06 25.5 0.2 0.41 10.0 0.0 3.2 2 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 KIY71115.1 - 1e-05 26.1 1.5 0.007 16.9 0.0 3.2 3 0 0 3 3 3 1 ABC transporter AAA_14 PF13173.6 KIY71115.1 - 1.5e-05 25.1 0.0 0.044 13.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 KIY71115.1 - 1.8e-05 24.3 0.0 0.037 13.6 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_18 PF13238.6 KIY71115.1 - 1.9e-05 25.2 0.0 0.21 12.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 KIY71115.1 - 5.5e-05 23.5 3.7 0.81 9.9 0.0 4.8 4 1 0 4 4 4 2 AAA domain RsgA_GTPase PF03193.16 KIY71115.1 - 0.00016 21.6 0.0 0.52 10.2 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase IstB_IS21 PF01695.17 KIY71115.1 - 0.00023 20.9 0.1 0.51 10.1 0.0 2.8 3 0 0 3 3 2 2 IstB-like ATP binding protein AAA_24 PF13479.6 KIY71115.1 - 0.00024 20.9 0.0 0.21 11.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 KIY71115.1 - 0.00035 20.3 0.9 0.97 9.2 0.0 3.6 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Roc PF08477.13 KIY71115.1 - 0.00056 20.1 0.0 0.47 10.7 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase ATPase_2 PF01637.18 KIY71115.1 - 0.001 19.1 8.6 1.2 9.0 0.0 4.3 3 2 2 5 5 5 2 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 KIY71115.1 - 0.0036 17.7 0.0 2.5 8.5 0.0 2.7 2 0 0 2 2 2 1 RNA helicase NACHT PF05729.12 KIY71115.1 - 0.0086 16.0 0.0 0.58 10.0 0.0 2.5 2 0 0 2 2 2 1 NACHT domain T2SSE PF00437.20 KIY71115.1 - 0.0098 15.0 0.0 0.043 12.9 0.0 2.0 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_25 PF13481.6 KIY71115.1 - 0.012 15.1 0.0 0.37 10.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KIY71115.1 - 0.014 14.7 0.1 6.6 5.9 0.0 3.0 3 0 0 3 3 3 0 Zeta toxin AAA_19 PF13245.6 KIY71115.1 - 0.016 15.5 0.9 0.55 10.6 0.0 3.1 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KIY71115.1 - 0.017 14.8 0.0 7.4 6.4 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain Bac_DnaA PF00308.18 KIY71115.1 - 0.018 14.9 0.0 8 6.2 0.0 2.4 2 0 0 2 2 2 0 Bacterial dnaA protein TsaE PF02367.17 KIY71115.1 - 0.027 14.5 0.0 8.4 6.4 0.0 2.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MCM PF00493.23 KIY71115.1 - 0.033 13.3 0.3 2.9 6.9 0.0 3.0 2 1 0 2 2 2 0 MCM P-loop domain DNA_pol3_delta2 PF13177.6 KIY71115.1 - 0.036 13.8 0.0 0.65 9.8 0.0 2.7 1 1 0 1 1 1 0 DNA polymerase III, delta subunit AAA_3 PF07726.11 KIY71115.1 - 0.037 13.9 0.2 9 6.2 0.1 3.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KIY71115.1 - 0.04 13.6 0.5 6.2 6.5 0.0 3.4 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KIY71115.1 - 0.062 13.5 0.1 15 5.7 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 KIY71115.1 - 0.064 13.0 3.5 25 4.6 0.0 3.5 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system SRP54 PF00448.22 KIY71115.1 - 0.079 12.6 0.9 2.4 7.7 0.0 2.8 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain PduV-EutP PF10662.9 KIY71115.1 - 0.087 12.6 0.0 0.8 9.4 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 KIY71115.1 - 0.096 12.8 0.1 18 5.5 0.0 2.9 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_23 PF13476.6 KIY71115.1 - 0.4 11.2 15.6 1.1 9.7 0.0 3.2 2 1 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KIY71115.1 - 0.83 9.5 4.6 13 5.6 0.0 3.5 5 0 0 5 5 2 0 NTPase AAA_17 PF13207.6 KIY71115.1 - 1.3 9.4 4.6 18 5.8 0.2 3.6 3 1 0 3 3 3 0 AAA domain FliJ PF02050.16 KIY71115.1 - 8.9 6.6 11.0 1.2 9.3 6.0 2.1 2 0 0 2 2 1 0 Flagellar FliJ protein MFS_1 PF07690.16 KIY71116.1 - 3.5e-33 115.0 21.4 4.7e-32 111.3 20.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KIY71116.1 - 3.7e-05 23.2 1.8 6e-05 22.5 0.2 2.0 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB RE_SinI PF09570.10 KIY71116.1 - 0.055 12.7 0.0 0.09 12.0 0.0 1.4 1 0 0 1 1 1 0 SinI restriction endonuclease AA_permease PF00324.21 KIY71117.1 - 2.8e-109 365.9 40.5 3.5e-109 365.5 40.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KIY71117.1 - 5.9e-30 104.4 47.3 6.9e-30 104.2 47.3 1.0 1 0 0 1 1 1 1 Amino acid permease PAS_3 PF08447.12 KIY71118.1 - 0.063 13.6 0.0 0.18 12.1 0.0 1.7 1 0 0 1 1 1 0 PAS fold HATPase_c PF02518.26 KIY71120.1 - 2.6e-46 156.8 0.1 5.5e-23 81.6 0.2 2.6 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KIY71120.1 - 1.3e-43 147.7 0.2 2.4e-21 76.0 0.0 2.6 2 0 0 2 2 2 2 Response regulator receiver domain HisKA PF00512.25 KIY71120.1 - 1.4e-19 69.8 0.1 2.6e-11 43.4 0.1 3.4 2 1 0 2 2 2 2 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 KIY71120.1 - 0.00042 20.2 0.0 0.0067 16.3 0.0 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_8 PF13188.7 KIY71120.1 - 0.00081 19.3 0.1 0.0058 16.6 0.0 2.5 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 KIY71120.1 - 0.0022 18.2 0.0 2.5 8.4 0.0 2.9 2 0 0 2 2 2 2 PAS fold PAS PF00989.25 KIY71120.1 - 0.038 14.0 0.0 0.091 12.8 0.0 1.7 1 0 0 1 1 1 0 PAS fold O-FucT PF10250.9 KIY71121.1 - 9.2e-09 35.4 0.0 8.1e-07 29.0 0.0 2.8 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Hydrolase_like PF13242.6 KIY71122.1 - 1.7e-23 82.5 0.0 6.1e-23 80.7 0.0 2.0 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 KIY71122.1 - 9.8e-19 67.3 0.0 1.7e-18 66.6 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KIY71122.1 - 0.0027 17.8 0.0 0.014 15.5 0.0 2.0 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KIY71122.1 - 0.0047 17.3 0.0 4.3 7.6 0.0 2.5 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase MyTH4 PF00784.17 KIY71123.1 - 1.1e-29 103.0 0.0 2.5e-29 101.9 0.0 1.6 1 0 0 1 1 1 1 MyTH4 domain RhoGAP PF00620.27 KIY71123.1 - 4e-28 98.2 0.0 7e-28 97.4 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain WW PF00397.26 KIY71123.1 - 8.9e-10 38.5 4.8 8.8e-06 25.7 2.4 2.6 2 0 0 2 2 2 2 WW domain EIF_2_alpha PF07541.12 KIY71126.1 - 3.8e-35 120.5 0.0 6.7e-35 119.7 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 KIY71126.1 - 2.3e-12 47.1 0.8 4.7e-12 46.1 0.8 1.5 1 0 0 1 1 1 1 S1 RNA binding domain Hist_deacetyl PF00850.19 KIY71127.1 - 4.7e-89 298.9 0.0 7e-89 298.3 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.9 KIY71127.1 - 4.4e-34 117.8 0.0 7.4e-34 117.0 0.0 1.4 1 0 0 1 1 1 1 Arb2 domain p450 PF00067.22 KIY71128.1 - 1.1e-66 225.5 0.0 3.3e-66 223.9 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KIY71129.1 - 3.4e-68 230.5 0.0 4.2e-68 230.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 TBPIP PF07106.13 KIY71130.1 - 1.1e-09 38.1 0.0 2e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 TBPIP/Hop2 winged helix domain Phage_GP20 PF06810.11 KIY71130.1 - 0.0014 18.4 2.5 0.0022 17.8 2.5 1.2 1 0 0 1 1 1 1 Phage minor structural protein GP20 Lebercilin PF15619.6 KIY71130.1 - 0.011 15.4 0.9 0.018 14.7 0.9 1.2 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease ZapB PF06005.12 KIY71130.1 - 0.045 14.2 3.1 0.099 13.1 3.1 1.6 1 1 0 1 1 1 0 Cell division protein ZapB DivIC PF04977.15 KIY71130.1 - 0.49 10.2 2.0 1.1 9.1 2.0 1.6 1 1 0 1 1 1 0 Septum formation initiator Ras PF00071.22 KIY71131.1 - 2.7e-50 170.1 0.0 3.3e-50 169.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIY71131.1 - 1.7e-23 83.1 0.0 4.8e-23 81.7 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIY71131.1 - 3.2e-06 26.7 0.0 5.2e-06 26.0 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KIY71131.1 - 0.012 15.1 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit CSRNP_N PF16019.5 KIY71131.1 - 0.046 13.6 0.0 0.18 11.7 0.0 1.9 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus AAA_16 PF13191.6 KIY71131.1 - 0.2 12.0 0.0 0.45 10.9 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.9 KIY71131.1 - 0.21 11.4 0.0 7.2 6.3 0.0 2.6 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Fe-S_biosyn PF01521.20 KIY71132.1 - 1.9e-12 47.4 0.0 6.8e-12 45.6 0.0 1.7 2 0 0 2 2 2 1 Iron-sulphur cluster biosynthesis CotE PF10628.9 KIY71132.1 - 0.062 12.9 0.1 0.089 12.4 0.1 1.2 1 0 0 1 1 1 0 Outer spore coat protein E (CotE) Peptidase_M22 PF00814.25 KIY71133.1 - 1.1e-67 228.6 0.1 1.3e-67 228.3 0.1 1.0 1 0 0 1 1 1 1 Glycoprotease family ketoacyl-synt PF00109.26 KIY71133.1 - 0.00089 18.9 0.0 0.0014 18.3 0.0 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain DUF5535 PF17687.1 KIY71133.1 - 0.16 12.2 0.0 28 4.9 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5535) Bestrophin PF01062.21 KIY71134.1 - 5.5e-35 121.2 0.7 3.7e-20 72.5 0.0 2.2 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel Ank_2 PF12796.7 KIY71135.1 - 5.4e-21 75.0 0.0 4.5e-13 49.6 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KIY71135.1 - 2.3e-18 66.3 0.1 3.6e-08 33.8 0.0 3.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIY71135.1 - 3.6e-11 42.3 0.2 0.0024 18.2 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 KIY71135.1 - 1.3e-10 41.2 2.1 0.00023 21.5 0.1 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KIY71135.1 - 1.7e-09 37.8 0.2 0.00082 19.6 0.0 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) DUF3544 PF12064.8 KIY71135.1 - 0.031 14.6 8.7 1.2 9.3 2.6 3.3 2 0 0 2 2 2 0 Protein kinase C-binding protein 1 YCII PF03795.14 KIY71136.1 - 2.2e-07 31.2 0.0 2.6e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain 2-Hacid_dh_C PF02826.19 KIY71137.1 - 4.1e-55 185.9 0.0 6.1e-55 185.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KIY71137.1 - 1.4e-07 31.2 0.0 1.9e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KIY71137.1 - 0.011 15.9 0.0 0.017 15.3 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 KIY71137.1 - 0.039 14.0 0.0 0.23 11.5 0.0 2.1 2 1 1 3 3 3 0 Shikimate / quinate 5-dehydrogenase AMP-binding PF00501.28 KIY71138.1 - 4.1e-91 305.7 0.0 5.5e-91 305.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KIY71138.1 - 1.2e-15 58.2 0.1 4e-15 56.6 0.1 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain BTB PF00651.31 KIY71139.1 - 9.6e-05 22.6 0.0 0.00022 21.4 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Ribosomal_L39 PF00832.20 KIY71140.1 - 2.4e-23 81.5 9.0 2.8e-23 81.3 9.0 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein Nmad3 PF18754.1 KIY71140.1 - 0.021 14.4 0.3 0.021 14.4 0.3 1.0 1 0 0 1 1 1 0 Nucleotide modification associated domain 3 Fungal_trans PF04082.18 KIY71141.1 - 9.5e-18 64.2 0.1 1.5e-17 63.6 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY71141.1 - 2.5e-07 30.7 8.5 4.2e-07 30.0 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain YTH PF04146.15 KIY71142.1 - 9.5e-62 207.8 3.0 3.9e-61 205.8 3.0 2.1 1 1 0 1 1 1 1 YT521-B-like domain RRM_1 PF00076.22 KIY71142.1 - 5.7e-05 22.9 0.0 0.00012 21.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ABC_membrane PF00664.23 KIY71143.1 - 1.6e-73 247.8 24.0 1.3e-36 126.7 7.0 2.5 2 1 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KIY71143.1 - 1.9e-62 209.8 0.0 2e-31 109.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KIY71143.1 - 6.1e-12 45.4 3.6 0.00088 18.8 0.7 4.2 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KIY71143.1 - 5.7e-10 39.8 0.1 8.4e-05 23.0 0.1 2.9 3 0 0 3 3 2 2 AAA ATPase domain AAA_21 PF13304.6 KIY71143.1 - 1e-09 38.7 0.1 0.034 14.0 0.0 4.3 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KIY71143.1 - 1e-08 35.5 0.7 0.012 15.9 0.0 4.0 2 2 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 KIY71143.1 - 4.6e-07 29.7 0.1 1.6 8.4 0.0 4.3 4 0 0 4 4 4 2 IstB-like ATP binding protein AAA_29 PF13555.6 KIY71143.1 - 5.2e-07 29.3 0.1 0.0075 16.0 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.9 KIY71143.1 - 8e-07 28.2 1.1 0.025 13.4 0.1 3.4 4 0 0 4 4 4 2 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 KIY71143.1 - 9e-07 28.9 0.0 0.05 13.5 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase RNA_helicase PF00910.22 KIY71143.1 - 2.5e-05 24.6 0.0 0.19 12.1 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_23 PF13476.6 KIY71143.1 - 2.6e-05 24.8 0.1 0.11 12.9 0.1 2.4 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 KIY71143.1 - 3.9e-05 23.0 0.0 0.3 10.3 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_30 PF13604.6 KIY71143.1 - 4.7e-05 23.2 0.0 0.2 11.4 0.0 3.4 3 1 0 3 3 3 2 AAA domain AAA_18 PF13238.6 KIY71143.1 - 0.00024 21.7 0.0 0.47 11.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 KIY71143.1 - 0.00044 20.1 0.0 0.44 10.2 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain G-alpha PF00503.20 KIY71143.1 - 0.00044 19.5 0.0 0.59 9.2 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit DUF87 PF01935.17 KIY71143.1 - 0.00052 20.2 0.1 0.21 11.6 0.0 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_28 PF13521.6 KIY71143.1 - 0.00091 19.5 0.8 0.42 10.8 0.0 3.1 3 0 0 3 3 2 1 AAA domain AAA_5 PF07728.14 KIY71143.1 - 0.0014 18.7 0.1 1.4 9.0 0.0 3.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) SbcCD_C PF13558.6 KIY71143.1 - 0.0016 18.7 0.2 4.9 7.5 0.1 3.4 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Rad17 PF03215.15 KIY71143.1 - 0.003 17.5 0.0 0.046 13.6 0.0 2.3 2 0 0 2 2 2 1 Rad17 P-loop domain PRK PF00485.18 KIY71143.1 - 0.0043 16.8 0.1 0.22 11.2 0.0 2.5 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family NB-ARC PF00931.22 KIY71143.1 - 0.0053 16.0 0.1 1.3 8.2 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain AAA_33 PF13671.6 KIY71143.1 - 0.0097 16.1 0.6 7.3 6.7 0.0 2.7 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KIY71143.1 - 0.011 15.8 0.0 7.3 6.7 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_25 PF13481.6 KIY71143.1 - 0.015 14.9 0.1 1.8 8.1 0.0 3.2 3 0 0 3 3 3 0 AAA domain APS_kinase PF01583.20 KIY71143.1 - 0.019 14.9 0.1 6.6 6.6 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase Rop-like PF05082.13 KIY71143.1 - 0.036 13.9 0.0 2.2 8.2 0.0 2.7 2 0 0 2 2 2 0 Rop-like AAA_24 PF13479.6 KIY71143.1 - 0.038 13.7 0.0 4.5 6.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 KIY71143.1 - 0.059 12.8 0.0 30 3.9 0.0 3.7 4 0 0 4 4 4 0 Bacterial TniB protein AAA_7 PF12775.7 KIY71143.1 - 0.076 12.5 0.0 9.8 5.6 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region ATPase PF06745.13 KIY71143.1 - 0.085 12.2 0.4 15 4.9 0.0 2.7 3 0 0 3 3 2 0 KaiC CoaE PF01121.20 KIY71143.1 - 0.093 12.4 0.7 9.7 5.8 0.0 2.4 2 0 0 2 2 2 0 Dephospho-CoA kinase Sigma54_activat PF00158.26 KIY71143.1 - 0.11 12.2 0.0 18 5.0 0.0 2.6 3 0 0 3 3 2 0 Sigma-54 interaction domain Mg_chelatase PF01078.21 KIY71143.1 - 0.12 11.7 0.0 2.2 7.6 0.0 2.6 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.6 KIY71143.1 - 0.12 12.4 0.0 21 5.2 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain CPT PF07931.12 KIY71143.1 - 0.14 12.0 0.1 21 4.9 0.0 2.4 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA PF00004.29 KIY71143.1 - 0.14 12.6 0.0 7.9 6.9 0.0 3.5 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) DUF3987 PF13148.6 KIY71143.1 - 0.19 10.7 0.1 1.2 8.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) DUF2075 PF09848.9 KIY71143.1 - 0.24 10.6 0.0 17 4.5 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) GDPD PF03009.17 KIY71144.1 - 6.3e-31 108.0 0.0 1.1e-30 107.3 0.0 1.4 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 KIY71144.1 - 0.0085 16.5 1.3 0.018 15.5 0.1 2.2 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family HEAT PF02985.22 KIY71145.1 - 1.4e-09 37.3 0.0 0.19 12.1 0.0 5.9 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.6 KIY71145.1 - 2.3e-06 27.9 0.0 0.096 13.1 0.0 3.3 3 1 0 3 3 3 2 HEAT repeats Cnd1 PF12717.7 KIY71145.1 - 8.9e-06 25.8 0.1 0.00057 20.0 0.0 2.5 1 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Pkinase PF00069.25 KIY71145.1 - 3.5e-05 23.3 0.0 0.00011 21.7 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain HEAT_EZ PF13513.6 KIY71145.1 - 0.00098 19.6 0.3 2.5 8.7 0.0 4.5 3 2 2 5 5 5 1 HEAT-like repeat Pkinase_Tyr PF07714.17 KIY71145.1 - 0.0029 16.9 0.0 0.0045 16.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Adaptin_N PF01602.20 KIY71145.1 - 0.0069 15.0 0.0 0.11 11.1 0.0 2.1 1 1 1 2 2 2 2 Adaptin N terminal region SLAC1 PF03595.17 KIY71146.1 - 5.9e-56 190.1 42.1 6.8e-56 189.9 42.1 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF21 PF01595.20 KIY71146.1 - 0.22 11.2 8.4 0.65 9.7 0.9 3.0 3 0 0 3 3 3 0 Cyclin M transmembrane N-terminal domain Med14 PF08638.11 KIY71148.1 - 8.3e-63 211.3 0.2 1.4e-62 210.6 0.2 1.4 1 0 0 1 1 1 1 Mediator complex subunit MED14 DASH_Dad2 PF08654.10 KIY71149.1 - 2.8e-06 27.7 0.1 5e-06 26.9 0.1 1.4 1 1 0 1 1 1 1 DASH complex subunit Dad2 EOS1 PF12326.8 KIY71150.1 - 1.5e-24 86.9 14.6 9.6e-21 74.5 11.6 2.3 1 1 1 2 2 2 2 N-glycosylation protein PH_9 PF15410.6 KIY71151.1 - 5.9e-27 94.4 0.0 1.1e-26 93.5 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain Sec7 PF01369.20 KIY71151.1 - 6.8e-25 87.8 0.0 1.3e-24 86.9 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain PH PF00169.29 KIY71151.1 - 0.001 19.5 0.0 0.0068 16.9 0.0 2.3 2 1 0 2 2 2 1 PH domain Oxysterol_BP PF01237.18 KIY71152.1 - 7.4e-133 443.0 0.1 2e-132 441.5 0.0 1.8 2 0 0 2 2 2 1 Oxysterol-binding protein Ank_2 PF12796.7 KIY71152.1 - 2.5e-12 47.2 0.1 2.4e-09 37.6 0.0 2.7 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KIY71152.1 - 1.1e-11 43.8 0.3 0.0015 18.8 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat PH PF00169.29 KIY71152.1 - 3.9e-11 43.4 0.1 1.3e-10 41.7 0.1 2.0 2 0 0 2 2 2 1 PH domain Ank_4 PF13637.6 KIY71152.1 - 6.5e-10 39.4 0.1 1.5e-05 25.5 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KIY71152.1 - 1e-09 38.4 0.0 0.002 18.4 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KIY71152.1 - 1.1e-09 38.3 2.2 0.00044 20.6 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat PH_8 PF15409.6 KIY71152.1 - 4e-07 30.2 1.4 2.3e-06 27.8 0.2 2.6 2 0 0 2 2 2 1 Pleckstrin homology domain HTH_Tnp_Tc5 PF03221.16 KIY71153.1 - 6.2e-05 22.9 0.0 0.0001 22.3 0.0 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_1 PF03184.19 KIY71154.1 - 3.4e-17 62.7 0.0 5.2e-17 62.1 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KIY71154.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 DDE superfamily endonuclease API5 PF05918.11 KIY71154.1 - 0.23 10.2 1.0 0.33 9.7 1.0 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) GATA PF00320.27 KIY71156.1 - 5e-18 64.4 2.7 5e-18 64.4 2.7 1.9 2 0 0 2 2 2 1 GATA zinc finger DUF1752 PF08550.10 KIY71156.1 - 9.6e-12 44.5 1.5 2.5e-11 43.2 1.5 1.8 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Peptidase_A22B PF04258.13 KIY71157.1 - 7.7e-77 258.6 1.8 1e-76 258.2 1.8 1.0 1 0 0 1 1 1 1 Signal peptide peptidase SPP PF06550.11 KIY71157.1 - 0.0024 17.4 6.4 0.0024 17.4 6.4 2.3 2 1 0 2 2 2 1 Signal-peptide peptidase, presenilin aspartyl protease SPC25 PF06703.11 KIY71157.1 - 0.16 11.7 2.0 0.18 11.6 0.1 2.0 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Ntox1 PF15500.6 KIY71159.1 - 0.84 10.0 6.2 12 6.4 0.5 2.6 2 0 0 2 2 2 0 Putative RNase-like toxin, toxin_1 MFS_1 PF07690.16 KIY71160.1 - 1.3e-31 109.9 40.6 1.7e-30 106.2 34.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 KIY71161.1 - 1.1e-28 100.2 44.0 1.5e-27 96.5 34.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.18 KIY71162.1 - 5.9e-16 58.3 0.0 8.8e-16 57.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DDE_1 PF03184.19 KIY71164.1 - 3.5e-06 26.8 0.0 7e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Myb_DNA-binding PF00249.31 KIY71166.1 - 5.2e-36 122.6 1.0 8.4e-11 41.9 0.2 3.2 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KIY71166.1 - 4.5e-28 97.3 0.0 1.5e-12 47.6 0.0 3.1 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KIY71166.1 - 0.0014 18.5 0.0 1.1 9.2 0.0 2.4 2 0 0 2 2 2 2 Myb DNA-binding like Myb_DNA-bind_2 PF08914.11 KIY71166.1 - 0.0027 17.9 0.1 0.97 9.7 0.0 2.7 2 1 0 2 2 2 2 Rap1 Myb domain MADF_DNA_bdg PF10545.9 KIY71166.1 - 0.1 12.9 0.1 27 5.2 0.0 3.2 3 0 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like PP_M1 PF03012.14 KIY71167.1 - 2.1 7.8 8.6 1.6 8.2 7.2 1.4 1 1 0 1 1 1 0 Phosphoprotein Presenilin PF01080.17 KIY71167.1 - 5.4 5.7 5.7 6.8 5.3 5.7 1.1 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 KIY71167.1 - 5.6 6.7 9.5 7.8 6.2 9.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Actin PF00022.19 KIY71168.1 - 4.9e-32 111.0 0.0 2.3e-31 108.9 0.0 1.8 1 1 0 1 1 1 1 Actin NUDIX PF00293.28 KIY71170.1 - 1.3e-09 38.2 0.0 3.5e-09 36.8 0.0 1.9 1 1 0 1 1 1 1 NUDIX domain Fra10Ac1 PF09725.9 KIY71171.1 - 5.7e-47 158.9 0.7 7.5e-47 158.5 0.7 1.1 1 0 0 1 1 1 1 Folate-sensitive fragile site protein Fra10Ac1 Glyco_hydro_11 PF00457.17 KIY71171.1 - 0.027 14.1 0.0 0.035 13.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 11 NmrA PF05368.13 KIY71172.1 - 3.6e-12 46.4 0.0 4.1e-12 46.2 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KIY71172.1 - 4.2e-12 46.3 0.1 4.9e-12 46.1 0.1 1.0 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KIY71172.1 - 2.6e-05 23.5 0.9 0.00013 21.2 0.1 1.9 1 1 1 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.19 KIY71172.1 - 2.9e-05 23.2 0.5 4.6e-05 22.6 0.5 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.20 KIY71172.1 - 5e-05 23.4 0.1 7.6e-05 22.8 0.1 1.3 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.21 KIY71172.1 - 0.0023 17.4 0.2 0.012 15.1 0.2 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 KIY71172.1 - 0.0039 17.6 0.0 0.0045 17.4 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Ldh_1_N PF00056.23 KIY71172.1 - 0.0043 17.2 0.2 0.0047 17.0 0.2 1.1 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KIY71172.1 - 0.0066 16.5 0.1 0.0075 16.3 0.1 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ADH_zinc_N PF00107.26 KIY71172.1 - 0.014 15.4 0.2 0.018 15.0 0.2 1.1 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DXP_reductoisom PF02670.16 KIY71172.1 - 0.017 15.9 0.0 0.02 15.6 0.0 1.1 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase KR PF08659.10 KIY71172.1 - 0.03 14.2 0.0 0.038 13.9 0.0 1.2 1 0 0 1 1 1 0 KR domain GDP_Man_Dehyd PF16363.5 KIY71172.1 - 0.052 12.9 0.2 1.9 7.8 0.0 2.0 1 1 1 2 2 2 0 GDP-mannose 4,6 dehydratase IMPa_N_2 PF18650.1 KIY71172.1 - 0.054 12.8 0.2 0.066 12.5 0.2 1.1 1 0 0 1 1 1 0 Immunomodulating metalloprotease N-terminal domain PK_C PF02887.16 KIY71172.1 - 0.061 13.6 0.0 0.07 13.4 0.0 1.2 1 0 0 1 1 1 0 Pyruvate kinase, alpha/beta domain ThiF PF00899.21 KIY71172.1 - 0.4 10.0 3.7 0.32 10.3 0.7 1.9 1 1 1 2 2 2 0 ThiF family SNF2_N PF00176.23 KIY71173.1 - 8.5e-67 225.3 0.2 1.6e-66 224.4 0.2 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 KIY71173.1 - 6.6e-37 126.0 0.5 2.1e-36 124.4 0.5 2.0 1 0 0 1 1 1 1 SLIDE HAND PF09110.11 KIY71173.1 - 1.8e-25 89.9 0.6 1.8e-25 89.9 0.6 3.5 3 0 0 3 3 3 1 HAND Helicase_C PF00271.31 KIY71173.1 - 7.8e-19 68.1 0.8 1.3e-17 64.1 0.0 3.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIY71173.1 - 1.2e-10 41.7 0.0 4.2e-10 39.9 0.0 2.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KIY71173.1 - 1.8e-05 24.1 0.0 4.7e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 KIY71173.1 - 0.00044 20.1 0.0 0.0012 18.6 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase DBINO PF13892.6 KIY71173.1 - 0.00046 20.5 5.4 0.00046 20.5 5.4 3.1 4 0 0 4 4 4 1 DNA-binding domain SWI2_SNF2 PF18766.1 KIY71173.1 - 0.00068 19.4 0.0 0.002 17.9 0.0 1.8 1 1 0 1 1 1 1 SWI2/SNF2 ATPase AAA_14 PF13173.6 KIY71173.1 - 0.004 17.2 0.1 0.016 15.3 0.1 2.1 1 0 0 1 1 1 1 AAA domain DEAD_2 PF06733.15 KIY71173.1 - 0.073 12.7 0.2 0.17 11.5 0.2 1.6 1 0 0 1 1 1 0 DEAD_2 CCDC53 PF10152.9 KIY71173.1 - 2 8.8 5.1 32 4.9 3.8 2.6 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Phage_int_SAM_1 PF02899.17 KIY71174.1 - 0.47 10.8 2.8 0.53 10.6 0.0 2.5 3 0 0 3 3 3 0 Phage integrase, N-terminal SAM-like domain F-box-like PF12937.7 KIY71176.1 - 0.0042 16.9 0.1 0.011 15.6 0.1 1.8 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KIY71176.1 - 0.043 14.3 3.4 2.2 8.8 0.8 4.1 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) DUF3760 PF12586.8 KIY71176.1 - 0.12 12.6 0.1 0.33 11.2 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3760) Glyco_hydr_30_2 PF14587.6 KIY71177.1 - 1.5e-31 110.3 0.0 4.8e-31 108.7 0.0 1.6 1 1 1 2 2 2 1 O-Glycosyl hydrolase family 30 Glyco_hydro_30C PF17189.4 KIY71177.1 - 0.011 15.9 0.5 0.03 14.5 0.3 1.9 2 0 0 2 2 2 0 Glycosyl hydrolase family 30 beta sandwich domain Methyltransf_28 PF02636.17 KIY71178.1 - 1.5e-62 211.6 0.0 1.8e-62 211.4 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase eIF-6 PF01912.18 KIY71179.1 - 6.7e-83 276.9 0.2 6.7e-83 276.9 0.2 1.4 2 0 0 2 2 2 1 eIF-6 family p450 PF00067.22 KIY71180.1 - 1.8e-54 185.3 0.0 2.9e-54 184.6 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 PLDc_2 PF13091.6 KIY71182.1 - 6e-12 45.6 0.0 1e-06 28.7 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 KIY71182.1 - 5.9e-06 26.2 3.1 0.0061 16.7 0.5 3.0 3 0 0 3 3 3 2 Phospholipase D Active site motif BLF1 PF17752.1 KIY71183.1 - 0.019 14.2 0.3 0.031 13.6 0.3 1.2 1 0 0 1 1 1 0 Burkholderia lethal factor 1 SHMT PF00464.19 KIY71184.1 - 1.7e-173 576.8 0.0 2.1e-173 576.6 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 KIY71184.1 - 2e-05 23.9 0.0 4.6e-05 22.8 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KIY71184.1 - 0.00029 20.2 0.0 0.011 15.0 0.0 2.3 2 1 0 2 2 2 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KIY71184.1 - 0.081 12.2 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Peptidase_S9 PF00326.21 KIY71185.1 - 8e-46 156.2 0.3 1.2e-45 155.6 0.3 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KIY71185.1 - 2.8e-05 23.9 0.4 0.071 12.7 0.0 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold AXE1 PF05448.12 KIY71185.1 - 0.0018 17.1 0.2 0.16 10.6 0.2 2.2 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) WD40 PF00400.32 KIY71186.1 - 1.5e-18 66.8 7.8 0.00051 20.8 0.0 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY71186.1 - 4.8e-16 58.8 0.1 1.1e-06 28.8 0.1 4.2 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIY71186.1 - 7.8e-05 22.6 0.1 0.041 13.8 0.1 2.2 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A GST_N_3 PF13417.6 KIY71187.1 - 5.9e-19 68.3 0.0 9.8e-19 67.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KIY71187.1 - 5.1e-16 58.8 0.0 9.6e-16 57.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KIY71187.1 - 4e-12 46.2 0.0 7.5e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KIY71187.1 - 9.4e-11 41.8 0.0 1.6e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KIY71187.1 - 5.9e-05 23.0 0.0 9.5e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KIY71187.1 - 0.0015 18.7 0.0 0.0025 18.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 KIY71187.1 - 0.0015 18.7 0.0 0.0025 18.0 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin motB PF17613.2 KIY71187.1 - 0.072 13.0 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Modifier of transcription NAD_binding_10 PF13460.6 KIY71188.1 - 1.3e-09 38.2 0.1 1.7e-09 37.8 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KIY71188.1 - 2.7e-06 27.0 0.0 7.8e-06 25.5 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 KIY71188.1 - 0.00077 19.9 0.0 0.0014 19.1 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 KIY71188.1 - 0.16 11.1 0.0 17 4.5 0.0 2.2 1 1 0 2 2 2 0 Male sterility protein 3Beta_HSD PF01073.19 KIY71188.1 - 0.16 10.9 0.0 0.25 10.3 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family GPI-anchored PF10342.9 KIY71191.1 - 0.062 14.1 3.9 0.081 13.7 3.2 1.5 1 1 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family CMAS PF02353.20 KIY71193.1 - 8.3e-55 186.0 0.3 2.8e-41 141.6 0.1 2.1 2 0 0 2 2 2 2 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 KIY71193.1 - 8.5e-07 29.6 0.0 1.8e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.10 KIY71193.1 - 0.00025 20.8 0.0 0.00037 20.2 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_11 PF08241.12 KIY71193.1 - 0.00074 20.1 0.0 0.0016 19.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KIY71193.1 - 0.0022 17.6 0.0 0.0036 16.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 KIY71193.1 - 0.0049 17.6 0.0 0.0095 16.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KIY71193.1 - 0.013 15.2 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.9 KIY71193.1 - 0.015 15.1 0.1 0.031 14.0 0.0 1.5 2 0 0 2 2 2 0 Lysine methyltransferase DUF938 PF06080.12 KIY71193.1 - 0.056 13.2 0.1 0.092 12.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) HetR_C PF18460.1 KIY71193.1 - 0.075 13.0 0.5 0.37 10.7 0.1 2.2 2 0 0 2 2 2 0 Heterocyst differentiation regulator C-terminal Hood domain Methyltransf_24 PF13578.6 KIY71193.1 - 0.11 13.5 0.0 0.24 12.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_3 PF01596.17 KIY71193.1 - 0.11 11.6 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_23 PF13489.6 KIY71193.1 - 0.15 11.9 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain GPI-anchored PF10342.9 KIY71196.1 - 1.7e-05 25.5 0.1 2.2e-05 25.1 0.1 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family EBP PF05241.12 KIY71198.1 - 9e-66 220.7 7.6 1e-65 220.5 7.6 1.0 1 0 0 1 1 1 1 Emopamil binding protein DUF1129 PF06570.11 KIY71198.1 - 0.046 13.2 1.7 2.8 7.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) DSBA PF01323.20 KIY71199.1 - 2.2e-30 105.9 0.0 2.5e-30 105.7 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 KIY71199.1 - 0.0071 16.5 0.4 0.19 11.9 0.4 2.1 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_3 PF13192.6 KIY71199.1 - 0.019 15.0 0.0 0.19 11.8 0.0 2.4 2 0 0 2 2 2 0 Thioredoxin domain DUF1118 PF06549.12 KIY71199.1 - 0.06 13.7 0.0 0.11 12.8 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1118) HpcH_HpaI PF03328.14 KIY71200.1 - 2.8e-40 137.8 0.0 6.7e-40 136.6 0.0 1.6 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 KIY71200.1 - 8.1e-16 58.1 0.0 1.1e-08 34.6 0.0 2.1 1 1 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold zf-C3HC4_2 PF13923.6 KIY71201.1 - 0.016 15.0 9.5 0.037 13.9 9.5 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FNIP_N PF14636.6 KIY71201.1 - 0.024 15.6 0.2 0.032 15.2 0.2 1.1 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus FixQ PF05545.11 KIY71201.1 - 0.2 11.7 0.5 0.36 10.8 0.5 1.4 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ zf-RING_4 PF14570.6 KIY71201.1 - 1 9.2 11.4 3.3 7.6 11.4 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.6 KIY71201.1 - 1.9 8.9 12.9 4.1 7.8 12.3 1.9 1 1 1 2 2 2 0 Ring finger domain CTP_transf_like PF01467.26 KIY71202.1 - 5.9e-09 36.3 0.0 3.3e-08 33.8 0.0 2.0 2 0 0 2 2 2 1 Cytidylyltransferase-like B56 PF01603.20 KIY71202.1 - 0.16 10.9 0.1 0.23 10.4 0.1 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) CwfJ_C_2 PF04676.14 KIY71203.1 - 1.1e-33 116.0 1.2 9.8e-33 113.0 0.1 2.4 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.15 KIY71203.1 - 3.9e-31 107.5 0.1 5.6e-31 106.9 0.1 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Glyco_hydro_61 PF03443.14 KIY71206.1 - 9e-66 221.7 0.1 1.1e-65 221.5 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 APH PF01636.23 KIY71207.1 - 0.037 13.9 0.0 0.061 13.2 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Glyco_hydro_15 PF00723.21 KIY71208.1 - 1.1e-48 166.1 0.0 2.9e-48 164.8 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 PAH PF02671.21 KIY71210.1 - 0.0063 16.6 0.0 0.009 16.1 0.0 1.4 1 0 0 1 1 1 1 Paired amphipathic helix repeat Coprogen_oxidas PF01218.18 KIY71211.1 - 1.5e-122 408.0 0.0 1.7e-122 407.8 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase SAICAR_synt PF01259.18 KIY71212.1 - 4.5e-102 341.0 0.0 5.4e-102 340.7 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase AAA PF00004.29 KIY71213.1 - 2.6e-40 137.9 0.0 4.9e-40 137.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KIY71213.1 - 1.7e-20 72.7 0.1 3.5e-20 71.7 0.1 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 KIY71213.1 - 2.3e-09 36.9 0.2 5.2e-09 35.8 0.2 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KIY71213.1 - 4.2e-05 24.0 0.3 0.015 15.7 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 KIY71213.1 - 0.00012 22.1 0.1 0.0007 19.6 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KIY71213.1 - 0.00046 20.3 0.3 0.0052 16.9 0.0 2.4 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 KIY71213.1 - 0.00088 19.0 0.0 0.0022 17.8 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KIY71213.1 - 0.00099 19.4 0.4 0.097 13.0 0.0 2.6 1 1 1 2 2 2 1 AAA domain PhoH PF02562.16 KIY71213.1 - 0.0033 16.9 0.1 0.069 12.6 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein AAA_11 PF13086.6 KIY71213.1 - 0.0054 16.6 0.1 0.37 10.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 KIY71213.1 - 0.0085 15.5 0.2 0.036 13.4 0.0 2.1 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KIY71213.1 - 0.01 16.0 0.0 0.028 14.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KIY71213.1 - 0.029 14.1 0.1 0.062 13.0 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.6 KIY71213.1 - 0.071 12.8 0.1 0.2 11.3 0.1 1.8 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.13 KIY71213.1 - 0.08 12.1 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) XhlA PF10779.9 KIY71213.1 - 1.6 9.0 5.9 36 4.7 4.4 2.6 2 0 0 2 2 2 0 Haemolysin XhlA NuA4 PF09340.10 KIY71214.1 - 7.3e-26 89.9 1.7 1.3e-25 89.0 1.7 1.4 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 DUF4407 PF14362.6 KIY71214.1 - 0.051 12.9 1.8 0.074 12.4 1.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF805 PF05656.14 KIY71215.1 - 5.3 7.5 7.4 16 6.0 7.2 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF805) DUF4218 PF13960.6 KIY71216.1 - 0.079 12.6 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) Dsl1_C PF11989.8 KIY71217.1 - 0.0046 16.7 1.0 0.011 15.4 0.4 1.7 1 1 1 2 2 2 1 Retrograde transport protein Dsl1 C terminal FAT PF02259.23 KIY71217.1 - 0.0093 15.2 0.0 0.0096 15.2 0.0 1.1 1 0 0 1 1 1 1 FAT domain DUF1571 PF07608.11 KIY71217.1 - 0.017 14.6 0.9 0.022 14.2 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1571) Ig_Tie2_1 PF10430.9 KIY71217.1 - 0.17 12.3 0.8 0.3 11.5 0.1 1.7 2 0 0 2 2 2 0 Tie-2 Ig-like domain 1 RRM_1 PF00076.22 KIY71219.1 - 2.2e-05 24.2 0.0 0.06 13.2 0.0 3.0 2 2 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cu-oxidase_3 PF07732.15 KIY71220.1 - 8.8e-27 93.5 0.1 7.5e-26 90.5 0.0 2.5 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KIY71220.1 - 2.4e-24 85.6 4.2 2.9e-20 72.4 0.4 3.6 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 KIY71220.1 - 2.1e-10 40.9 0.0 7.6e-10 39.1 0.0 1.9 2 1 0 2 2 2 1 Multicopper oxidase RPN6_C_helix PF18503.1 KIY71220.1 - 0.1 12.4 0.4 0.18 11.6 0.4 1.4 1 0 0 1 1 1 0 26S proteasome subunit RPN6 C-terminal helix domain MFS_1 PF07690.16 KIY71221.1 - 7.5e-34 117.2 41.0 1.4e-28 99.8 8.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KIY71221.1 - 0.41 9.0 15.7 0.087 11.2 0.8 2.2 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) ESCRT-II PF05871.12 KIY71222.1 - 6.3e-29 101.0 0.1 8.4e-29 100.6 0.1 1.1 1 0 0 1 1 1 1 ESCRT-II complex subunit Phage_holin_2_3 PF16080.5 KIY71222.1 - 0.35 10.7 1.5 3.8 7.4 0.0 2.8 3 0 0 3 3 3 0 Bacteriophage holin family HP1 Amidohydro_3 PF07969.11 KIY71223.1 - 1.1e-11 44.9 0.3 3.2e-05 23.6 0.0 2.8 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.20 KIY71223.1 - 3.9e-11 42.8 0.0 1.3e-07 31.3 0.0 2.5 2 0 0 2 2 2 2 Amidohydrolase family DUF4770 PF15994.5 KIY71224.1 - 3.1 8.0 6.1 0.48 10.6 0.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) FKS1_dom1 PF14288.6 KIY71225.1 - 0.032 14.6 0.3 0.052 13.9 0.3 1.3 1 0 0 1 1 1 0 1,3-beta-glucan synthase subunit FKS1, domain-1 Ytp1 PF10355.9 KIY71226.1 - 2.7e-100 335.1 7.0 4.7e-100 334.4 7.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 KIY71226.1 - 6.9e-15 54.7 1.5 6.9e-15 54.7 1.5 2.6 4 0 0 4 4 4 1 Domain of unknown function (DUF2427) CLIP_SPH_mas PF18398.1 KIY71227.1 - 0.048 14.1 1.1 0.12 12.8 1.1 1.7 1 0 0 1 1 1 0 Clip-domain serine protease homolog masquerade MFS_1 PF07690.16 KIY71228.1 - 1.7e-25 89.7 49.2 1.3e-22 80.2 15.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Ribosomal_L22 PF00237.19 KIY71229.1 - 2.1e-36 124.3 0.2 2.8e-36 123.9 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e RE_Eco29kI PF09517.10 KIY71229.1 - 0.0023 17.6 0.0 0.0032 17.1 0.0 1.2 1 0 0 1 1 1 1 Eco29kI restriction endonuclease Minor_tail_Z PF06763.11 KIY71229.1 - 0.024 14.5 0.2 0.024 14.5 0.2 1.5 2 0 0 2 2 2 0 Prophage minor tail protein Z (GPZ) Asp_Glu_race_2 PF14669.6 KIY71229.1 - 0.13 11.9 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Putative aspartate racemase p450 PF00067.22 KIY71230.1 - 1.7e-67 228.2 0.0 2.3e-67 227.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Eaf7 PF07904.13 KIY71231.1 - 2.5e-12 47.1 0.0 6.3e-12 45.8 0.0 1.7 1 0 0 1 1 1 1 Chromatin modification-related protein EAF7 RNA_polI_A34 PF08208.11 KIY71231.1 - 0.73 9.9 14.0 1 9.4 14.0 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Coilin_N PF15862.5 KIY71231.1 - 1.2 8.9 4.7 1.7 8.4 4.3 1.5 2 0 0 2 2 2 0 Coilin N-terminus Mob1_phocein PF03637.17 KIY71232.1 - 2.1e-59 200.3 1.6 2.5e-59 200.1 1.6 1.0 1 0 0 1 1 1 1 Mob1/phocein family LIDHydrolase PF10230.9 KIY71233.1 - 0.033 13.7 0.1 0.056 13.0 0.1 1.5 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Flavoprotein PF02441.19 KIY71234.1 - 8.3e-51 171.9 0.1 9.5e-51 171.7 0.1 1.0 1 0 0 1 1 1 1 Flavoprotein Copper-bind PF00127.20 KIY71235.1 - 0.0013 19.1 0.1 0.0028 18.1 0.1 1.5 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cu_bind_like PF02298.17 KIY71235.1 - 0.033 14.2 0.3 0.24 11.4 0.3 2.0 1 1 0 1 1 1 0 Plastocyanin-like domain Fungal_trans PF04082.18 KIY71236.1 - 8.3e-20 70.9 0.1 1.6e-19 70.0 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY71236.1 - 0.00036 20.6 12.3 0.00062 19.8 12.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PIP5K PF01504.18 KIY71237.1 - 7e-42 143.5 0.0 4.7e-31 108.0 0.0 2.3 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase HECT PF00632.25 KIY71238.1 - 1.7e-93 313.5 0.0 2.2e-93 313.1 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 KIY71238.1 - 2.3e-36 123.5 21.4 4.5e-12 45.8 0.5 3.5 3 0 0 3 3 3 3 WW domain C2 PF00168.30 KIY71238.1 - 8.7e-15 54.9 0.0 1.8e-14 53.9 0.0 1.5 1 0 0 1 1 1 1 C2 domain NPCBM_assoc PF10633.9 KIY71238.1 - 1.7 8.9 8.1 9.7 6.5 0.2 3.6 4 0 0 4 4 4 0 NPCBM-associated, NEW3 domain of alpha-galactosidase DUF3605 PF12239.8 KIY71239.1 - 2.6e-27 96.0 0.0 5e-19 69.1 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3605) adh_short PF00106.25 KIY71240.1 - 6e-21 74.8 0.0 1.7e-18 66.8 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KIY71240.1 - 2.9e-12 46.6 0.0 3.8e-11 43.0 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIY71240.1 - 1.3e-05 25.2 0.0 2.1e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 KR domain K_trans PF02705.16 KIY71241.1 - 5.3e-170 566.4 8.0 6.6e-170 566.1 8.0 1.1 1 0 0 1 1 1 1 K+ potassium transporter RICTOR_N PF14664.6 KIY71243.1 - 4.9e-116 387.8 1.9 8.8e-116 386.9 1.9 1.4 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.6 KIY71243.1 - 8.9e-41 137.9 0.5 2e-39 133.5 0.1 3.4 2 1 2 4 4 4 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.6 KIY71243.1 - 4.9e-35 120.2 0.0 9.4e-34 116.1 0.0 2.7 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.6 KIY71243.1 - 1.4e-28 99.0 0.1 6.4e-26 90.4 0.0 3.9 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.16 KIY71243.1 - 4.6e-06 26.7 3.2 4.6e-06 26.7 3.2 2.2 2 0 0 2 2 2 1 Hr1 repeat HEAT PF02985.22 KIY71243.1 - 0.00018 21.5 0.0 3.9 8.0 0.0 3.9 3 0 0 3 3 3 2 HEAT repeat F-box-like PF12937.7 KIY71244.1 - 9.1e-09 35.1 0.4 6.3e-08 32.4 0.0 2.6 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 KIY71244.1 - 0.049 14.1 5.5 14 6.3 0.0 4.9 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) PQ-loop PF04193.14 KIY71245.1 - 1.4e-29 101.7 14.4 6.2e-18 64.3 3.5 2.9 3 0 0 3 3 3 2 PQ loop repeat HTH_Bact PF18768.1 KIY71245.1 - 0.0019 17.7 0.3 1.8 8.2 0.0 2.4 2 0 0 2 2 2 2 Helix-turn-helix bacterial domain DUF5090 PF17009.5 KIY71245.1 - 0.0063 16.5 0.6 3.6 7.5 0.1 2.5 2 1 0 2 2 2 2 Domain of unknown function (DUF5090) Band_7 PF01145.25 KIY71246.1 - 2.7e-23 82.9 0.1 3.7e-23 82.5 0.1 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family MutS_V PF00488.21 KIY71247.1 - 9.3e-39 133.4 0.0 2e-38 132.3 0.0 1.5 1 1 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KIY71247.1 - 5.6e-32 111.5 0.1 1.2e-31 110.4 0.0 1.6 2 0 0 2 2 2 1 MutS domain III AAA PF00004.29 KIY71247.1 - 0.089 13.2 0.0 0.78 10.2 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF3556 PF12077.8 KIY71247.1 - 0.18 10.2 0.1 0.26 9.6 0.1 1.1 1 0 0 1 1 1 0 Transmembrane protein of unknown function (DUF3556) Mito_carr PF00153.27 KIY71248.1 - 1.3e-41 140.5 4.2 1.6e-15 56.8 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Abhydrolase_1 PF00561.20 KIY71249.1 - 5.8e-26 91.7 0.0 4.8e-22 78.8 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 KIY71249.1 - 1.1e-20 73.6 0.0 3.8e-20 71.9 0.0 1.9 2 0 0 2 2 2 1 TAP-like protein TPR_1 PF00515.28 KIY71250.1 - 6.3e-14 51.1 2.3 3.2e-07 29.9 0.6 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KIY71250.1 - 4.1e-12 45.2 6.4 4e-05 23.4 0.8 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 KIY71250.1 - 2.5e-09 36.7 1.9 1.7e-06 27.6 0.4 2.7 2 0 0 2 2 2 2 TPR repeat TPR_16 PF13432.6 KIY71250.1 - 3.5e-07 30.7 9.1 2.8e-05 24.6 3.0 3.0 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 KIY71250.1 - 2.2e-06 27.8 10.6 4.7e-05 23.6 2.3 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 KIY71250.1 - 5.3e-06 26.4 0.6 0.1 13.1 0.4 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 KIY71250.1 - 1.3e-05 25.2 0.4 4.4e-05 23.5 0.5 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 KIY71250.1 - 2.5e-05 24.7 6.0 0.00035 21.0 1.3 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 KIY71250.1 - 0.0001 22.0 0.2 0.029 14.4 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KIY71250.1 - 0.0022 18.7 4.2 1.4 9.9 1.2 4.1 3 1 2 5 5 3 1 Tetratricopeptide repeat Glyco_hydro_42M PF08532.10 KIY71250.1 - 0.017 14.7 2.2 15 5.0 0.1 4.4 5 0 0 5 5 5 0 Beta-galactosidase trimerisation domain TPR_10 PF13374.6 KIY71250.1 - 0.021 14.7 3.7 0.3 11.0 2.4 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3856 PF12968.7 KIY71250.1 - 0.026 14.6 0.2 0.064 13.3 0.2 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF3856) Coatomer_E PF04733.14 KIY71250.1 - 0.1 12.0 0.2 0.18 11.2 0.2 1.3 1 0 0 1 1 1 0 Coatomer epsilon subunit TPR_8 PF13181.6 KIY71250.1 - 0.13 12.5 6.3 1.2 9.5 0.2 3.9 4 0 0 4 4 3 0 Tetratricopeptide repeat DUF2194 PF09960.9 KIY71250.1 - 0.21 9.9 0.0 0.31 9.3 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2194) MgtE PF01769.16 KIY71251.1 - 3.4e-40 137.3 22.6 1.8e-21 76.8 8.6 3.0 3 0 0 3 3 3 2 Divalent cation transporter DUF1129 PF06570.11 KIY71251.1 - 1.4 8.4 6.4 0.37 10.2 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) SSF PF00474.17 KIY71252.1 - 1.2e-20 73.7 33.5 1.2e-20 73.7 33.5 1.7 2 0 0 2 2 2 1 Sodium:solute symporter family DUF4713 PF15831.5 KIY71252.1 - 1.3 9.6 6.2 1.4 9.4 0.4 3.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4713) Forkhead PF00250.18 KIY71253.1 - 6.4e-11 42.4 0.0 8.7e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 Forkhead domain AA_permease_2 PF13520.6 KIY71254.1 - 9.2e-54 182.9 45.9 1.1e-53 182.6 45.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KIY71254.1 - 2.3e-24 85.9 39.1 3e-24 85.5 39.1 1.0 1 0 0 1 1 1 1 Amino acid permease DUF2627 PF11118.8 KIY71254.1 - 0.36 11.4 3.1 1.8 9.2 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2627) RhoGEF PF00621.20 KIY71255.1 - 7.4e-40 137.1 0.6 1.2e-39 136.4 0.6 1.4 1 0 0 1 1 1 1 RhoGEF domain SH3_9 PF14604.6 KIY71255.1 - 3.5e-17 62.0 2.1 1.1e-08 34.8 0.4 2.6 2 0 0 2 2 2 2 Variant SH3 domain EF-hand_4 PF12763.7 KIY71255.1 - 4.5e-16 58.7 0.0 1e-15 57.5 0.0 1.5 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand SH3_1 PF00018.28 KIY71255.1 - 1e-14 53.8 7.0 1.4e-06 27.8 4.1 3.0 2 1 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 KIY71255.1 - 6.2e-14 51.4 1.3 3e-06 26.8 0.2 2.6 2 0 0 2 2 2 2 Variant SH3 domain WH2 PF02205.20 KIY71255.1 - 8.7e-10 38.1 0.7 1.8e-09 37.1 0.7 1.6 1 0 0 1 1 1 1 WH2 motif PH PF00169.29 KIY71255.1 - 0.00011 22.7 0.0 0.00022 21.7 0.0 1.5 1 0 0 1 1 1 1 PH domain EF-hand_1 PF00036.32 KIY71255.1 - 0.0022 17.4 0.2 1.1 9.0 0.2 2.6 2 0 0 2 2 2 2 EF hand PH_13 PF16652.5 KIY71255.1 - 0.0029 17.5 0.0 0.033 14.0 0.0 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain EF-hand_7 PF13499.6 KIY71255.1 - 0.013 16.0 0.0 0.013 16.0 0.0 2.5 3 0 0 3 3 3 0 EF-hand domain pair End3 PF12761.7 KIY71255.1 - 4.3 7.5 16.1 3.2 7.9 1.4 2.7 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 p450 PF00067.22 KIY71258.1 - 5.3e-63 213.4 0.0 1.4e-62 212.0 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 PX PF00787.24 KIY71259.1 - 4.6e-25 87.8 0.1 5.6e-25 87.5 0.1 1.1 1 0 0 1 1 1 1 PX domain p450 PF00067.22 KIY71261.1 - 2.1e-62 211.4 0.0 2.5e-61 207.9 0.0 2.2 1 1 0 1 1 1 1 Cytochrome P450 VPS9 PF02204.18 KIY71262.1 - 4.3e-19 68.6 0.0 8.4e-18 64.5 0.0 2.4 1 1 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain CENP-B_dimeris PF09026.10 KIY71262.1 - 0.76 10.2 8.5 1.9 8.9 8.5 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain CDC45 PF02724.14 KIY71262.1 - 1.6 6.9 6.8 2.3 6.4 6.8 1.1 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 KIY71262.1 - 2.8 7.2 4.3 4.3 6.6 4.3 1.2 1 0 0 1 1 1 0 NOA36 protein Pkinase PF00069.25 KIY71263.1 - 4e-27 95.2 0.0 9.4e-27 94.0 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY71263.1 - 5.8e-08 32.3 0.0 2.3e-07 30.4 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY71263.1 - 0.0077 15.6 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KIY71263.1 - 0.12 11.7 0.2 0.24 10.7 0.1 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Fungal_trans PF04082.18 KIY71266.1 - 1.6e-18 66.7 0.0 3e-18 65.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY71266.1 - 0.00018 21.5 13.5 0.00032 20.7 13.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain COX14 PF14880.6 KIY71267.1 - 0.0066 16.3 1.0 0.0088 15.9 1.0 1.3 1 1 0 1 1 1 1 Cytochrome oxidase c assembly Glyco_transf_28 PF03033.20 KIY71268.1 - 3.3e-24 85.5 0.0 6e-24 84.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 KIY71268.1 - 4.9e-06 25.6 0.0 7.6e-06 25.0 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase ATG_C PF09333.11 KIY71268.1 - 0.0094 16.3 0.0 0.024 14.9 0.0 1.7 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain Aspzincin_M35 PF14521.6 KIY71269.1 - 1.7e-40 138.9 2.5 1.7e-40 138.9 2.5 1.7 2 0 0 2 2 2 1 Lysine-specific metallo-endopeptidase HRXXH PF13933.6 KIY71269.1 - 0.0049 16.5 1.4 0.28 10.7 0.1 2.2 1 1 0 2 2 2 2 Putative peptidase family Oxidored_FMN PF00724.20 KIY71271.1 - 7.5e-92 308.2 0.0 8.6e-92 308.0 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Aspzincin_M35 PF14521.6 KIY71272.1 - 2.1e-43 148.4 10.4 2.1e-43 148.4 10.4 1.9 1 1 1 2 2 2 1 Lysine-specific metallo-endopeptidase MFS_1 PF07690.16 KIY71273.1 - 4.9e-33 114.5 42.3 3.2e-28 98.7 33.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KIY71273.1 - 3.7e-05 23.2 24.8 5.5e-05 22.6 24.8 1.2 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB TetR_C_16 PF17920.1 KIY71273.1 - 3.1 8.1 8.1 2.5 8.4 1.0 3.0 4 0 0 4 4 4 0 Tetracyclin repressor-like, C-terminal domain ECH_1 PF00378.20 KIY71274.1 - 2.6e-51 174.4 0.0 3.4e-51 174.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KIY71274.1 - 1.1e-20 74.4 0.0 1.3e-20 74.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Glyco_transf_28 PF03033.20 KIY71275.1 - 3.1e-22 79.1 0.0 7.7e-22 77.8 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 KIY71275.1 - 5.2e-08 32.1 0.1 9.7e-08 31.2 0.1 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase ATG_C PF09333.11 KIY71275.1 - 0.00065 20.0 0.2 0.0047 17.2 0.0 2.4 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain Glyco_tran_28_C PF04101.16 KIY71275.1 - 0.034 14.1 0.0 0.075 13.0 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain DUF1635 PF07795.11 KIY71275.1 - 0.29 11.0 4.8 0.52 10.1 4.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) TFB6 PF17110.5 KIY71276.1 - 0.033 13.9 0.1 1.3 8.7 0.1 2.5 2 1 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH adh_short_C2 PF13561.6 KIY71277.1 - 1.3e-45 155.8 0.0 2.1e-45 155.1 0.0 1.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIY71277.1 - 1.7e-44 151.6 0.4 2.8e-44 150.9 0.4 1.3 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIY71277.1 - 3.4e-07 30.3 0.0 5.5e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KIY71277.1 - 0.0029 16.8 0.1 0.0045 16.2 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3HCDH_N PF02737.18 KIY71277.1 - 0.0097 15.8 0.5 0.015 15.2 0.5 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 KIY71277.1 - 0.019 14.4 0.1 0.44 10.0 0.1 2.2 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_7 PF13241.6 KIY71277.1 - 0.022 15.2 0.2 0.042 14.3 0.2 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding THF_DHG_CYH_C PF02882.19 KIY71277.1 - 0.094 12.0 0.0 0.2 11.0 0.0 1.6 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ApbA PF02558.16 KIY71277.1 - 0.11 12.2 0.2 0.17 11.5 0.2 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Phage_T4_Ndd PF06591.11 KIY71277.1 - 0.12 12.1 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 T4-like phage nuclear disruption protein (Ndd) Pyr_redox PF00070.27 KIY71277.1 - 0.13 12.8 0.1 0.41 11.2 0.1 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase F-box-like PF12937.7 KIY71278.1 - 8e-08 32.1 0.0 2.4e-07 30.5 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY71278.1 - 0.02 14.7 0.0 1.3 9.0 0.0 2.7 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.7 KIY71279.1 - 2.1e-05 24.3 0.0 8.3e-05 22.4 0.0 2.1 1 0 0 1 1 1 1 F-box-like zf-MYND PF01753.18 KIY71280.1 - 2.4e-10 40.3 14.0 2.4e-10 40.3 14.0 2.3 2 0 0 2 2 2 1 MYND finger TPR_4 PF07721.14 KIY71280.1 - 0.015 15.9 0.0 0.073 13.7 0.0 2.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 KIY71280.1 - 0.019 15.3 0.0 2.1 8.7 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KIY71280.1 - 0.1 13.4 1.9 1.8 9.6 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KIY71280.1 - 0.69 10.7 2.9 30 5.5 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-C6H2 PF15801.5 KIY71280.1 - 6.8 7.1 13.2 2.2 8.6 9.2 2.3 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding Spc7 PF08317.11 KIY71281.1 - 0.002 17.1 5.0 0.0032 16.4 5.0 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein Atg14 PF10186.9 KIY71281.1 - 0.0024 17.0 5.5 0.0045 16.1 5.5 1.3 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Fez1 PF06818.15 KIY71281.1 - 0.01 16.3 3.9 0.017 15.6 3.7 1.5 1 1 0 1 1 1 0 Fez1 IFT57 PF10498.9 KIY71281.1 - 0.012 14.7 0.7 0.02 13.9 0.7 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 GAS PF13851.6 KIY71281.1 - 0.018 14.4 3.4 0.031 13.6 3.4 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF3552 PF12072.8 KIY71281.1 - 0.022 14.2 7.6 0.046 13.1 7.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Sec2p PF06428.11 KIY71281.1 - 0.058 13.4 3.4 0.14 12.1 2.6 2.1 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p Golgin_A5 PF09787.9 KIY71281.1 - 0.061 12.8 2.6 0.097 12.1 2.6 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 ATG16 PF08614.11 KIY71281.1 - 0.084 13.1 13.2 0.23 11.7 12.7 1.9 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF4407 PF14362.6 KIY71281.1 - 0.48 9.7 4.7 3.2 7.0 5.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) UPF0242 PF06785.11 KIY71281.1 - 0.72 9.9 5.7 1.9 8.5 2.3 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus HrpB7 PF09486.10 KIY71281.1 - 1.3 9.4 17.1 1.2 9.5 5.8 2.7 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) TMF_DNA_bd PF12329.8 KIY71281.1 - 2.4 8.2 8.7 1.8 8.6 2.2 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding SlyX PF04102.12 KIY71281.1 - 7.3 7.3 8.0 8.3 7.1 2.0 2.8 1 1 2 3 3 3 0 SlyX EHN PF06441.12 KIY71283.1 - 1.6e-08 34.9 0.1 3.9e-06 27.2 0.1 2.2 1 1 0 1 1 1 1 Epoxide hydrolase N terminus Homeodomain PF00046.29 KIY71285.1 - 2.2e-18 65.8 1.9 1.5e-06 28.0 0.2 3.4 3 0 0 3 3 3 3 Homeodomain Homeobox_KN PF05920.11 KIY71285.1 - 1.5e-06 28.0 1.9 0.027 14.3 0.0 3.4 3 0 0 3 3 3 2 Homeobox KN domain Adeno_E3_CR2 PF02439.15 KIY71287.1 - 0.0015 18.3 0.8 0.0025 17.5 0.8 1.3 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Phage_holin_2_3 PF16080.5 KIY71287.1 - 0.15 11.8 0.1 0.25 11.1 0.1 1.3 1 0 0 1 1 1 0 Bacteriophage holin family HP1 Amnionless PF14828.6 KIY71287.1 - 0.17 10.7 0.0 0.2 10.5 0.0 1.1 1 0 0 1 1 1 0 Amnionless Pkinase PF00069.25 KIY71289.1 - 5.1e-23 81.8 0.0 7.7e-23 81.2 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY71289.1 - 2.6e-05 23.6 0.0 4.3e-05 22.9 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KIY71289.1 - 0.0013 18.1 0.0 0.0024 17.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIY71289.1 - 0.0024 17.8 0.0 0.0091 15.9 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family MaAIMP_sms PF16951.5 KIY71289.1 - 0.037 13.8 0.0 0.086 12.6 0.0 1.5 1 0 0 1 1 1 0 Putative methionine and alanine importer, small subunit Seadorna_VP7 PF07387.11 KIY71289.1 - 0.045 12.8 0.0 0.066 12.3 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 EHN PF06441.12 KIY71290.1 - 1.7e-31 108.8 0.4 1.5e-30 105.7 0.0 2.1 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KIY71290.1 - 7.7e-14 51.9 0.0 1.2e-13 51.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIY71290.1 - 0.00083 20.0 1.0 0.0018 18.9 1.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family CAP PF00188.26 KIY71291.1 - 2.5e-20 73.6 4.7 3.7e-20 73.0 4.7 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family IR1-M PF12185.8 KIY71291.1 - 0.13 12.2 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Nup358/RanBP2 E3 ligase domain FNIP_N PF14636.6 KIY71292.1 - 0.26 12.2 5.4 0.44 11.5 5.4 1.2 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus RNA_Me_trans PF04252.13 KIY71294.1 - 5.1e-74 248.2 0.0 5.7e-74 248.0 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase EHN PF06441.12 KIY71295.1 - 3.2e-05 24.2 1.0 0.00011 22.6 1.0 1.7 1 1 0 1 1 1 1 Epoxide hydrolase N terminus DUF743 PF05332.11 KIY71295.1 - 0.032 14.3 0.1 0.04 14.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF743) IFT46_B_C PF12317.8 KIY71295.1 - 0.14 11.9 0.1 0.16 11.7 0.1 1.1 1 0 0 1 1 1 0 Intraflagellar transport complex B protein 46 C terminal Cellulase PF00150.18 KIY71296.1 - 5e-11 42.5 0.0 5.4e-07 29.3 0.0 2.8 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_5_C PF18564.1 KIY71296.1 - 5.3e-08 33.3 0.5 8.7e-07 29.4 0.1 2.5 2 0 0 2 2 2 1 Glycoside hydrolase family 5 C-terminal domain adh_short PF00106.25 KIY71297.1 - 3.4e-21 75.6 0.0 8.2e-20 71.1 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIY71297.1 - 1.1e-09 38.3 0.0 5.2e-09 36.0 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIY71297.1 - 7.6e-06 26.0 0.1 1.7e-05 24.8 0.1 1.6 1 1 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 KIY71297.1 - 6.6e-05 22.5 0.0 0.00023 20.7 0.1 1.7 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KIY71297.1 - 7.7e-05 22.3 0.0 0.00021 20.8 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 KIY71297.1 - 0.028 15.0 0.0 0.062 13.9 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Glyco_trans_4_2 PF13477.6 KIY71297.1 - 0.051 13.6 0.0 0.14 12.2 0.0 1.8 1 0 0 1 1 1 0 Glycosyl transferase 4-like CobU PF02283.16 KIY71297.1 - 0.089 12.4 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase THF_DHG_CYH_C PF02882.19 KIY71297.1 - 0.1 11.9 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain OPA3 PF07047.12 KIY71299.1 - 6.6e-45 151.9 0.1 9.9e-45 151.4 0.1 1.3 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) HSBP1 PF06825.12 KIY71299.1 - 0.00047 19.9 0.2 0.00047 19.9 0.2 1.6 2 0 0 2 2 2 1 Heat shock factor binding protein 1 Ax_dynein_light PF10211.9 KIY71299.1 - 0.065 13.2 1.0 0.11 12.5 1.0 1.3 1 0 0 1 1 1 0 Axonemal dynein light chain MctB PF11382.8 KIY71299.1 - 0.071 12.8 0.1 0.099 12.3 0.1 1.2 1 0 0 1 1 1 0 Copper transport outer membrane protein, MctB CLZ PF16526.5 KIY71299.1 - 0.073 13.4 0.7 0.14 12.5 0.7 1.5 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels SLX9 PF15341.6 KIY71299.1 - 0.076 13.4 0.2 0.13 12.7 0.2 1.3 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 DUF16 PF01519.16 KIY71299.1 - 0.08 13.4 0.5 0.15 12.5 0.2 1.5 2 0 0 2 2 2 0 Protein of unknown function DUF16 Syntaxin-6_N PF09177.11 KIY71299.1 - 0.087 13.4 0.3 0.15 12.6 0.3 1.3 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Homeodomain PF00046.29 KIY71300.1 - 8.9e-17 60.7 13.2 3.9e-06 26.6 0.2 4.7 5 0 0 5 5 5 4 Homeodomain Homeobox_KN PF05920.11 KIY71300.1 - 0.0011 18.8 5.7 6.6 6.7 0.1 4.6 4 0 0 4 4 4 2 Homeobox KN domain TerB_C PF15615.6 KIY71300.1 - 0.021 15.1 0.0 0.16 12.3 0.0 2.2 2 0 0 2 2 2 0 TerB-C domain RTA1 PF04479.13 KIY71301.1 - 1.1e-48 165.6 7.5 1.1e-48 165.6 7.5 1.6 2 0 0 2 2 2 1 RTA1 like protein Homeodomain PF00046.29 KIY71302.1 - 0.00053 19.8 0.1 0.0014 18.5 0.1 1.6 1 0 0 1 1 1 1 Homeodomain Pkinase PF00069.25 KIY71303.1 - 5.4e-20 71.8 0.0 6.6e-20 71.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KIY71303.1 - 0.00013 21.4 0.0 0.00018 20.9 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.17 KIY71303.1 - 0.00073 18.9 0.0 0.00089 18.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KIY71303.1 - 0.0027 17.1 0.0 0.0041 16.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIY71303.1 - 0.0087 16.0 0.0 0.012 15.6 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1794 PF08768.11 KIY71303.1 - 0.015 15.3 0.0 0.022 14.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1794) Seadorna_VP7 PF07387.11 KIY71303.1 - 0.11 11.6 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Choline_kinase PF01633.20 KIY71303.1 - 0.15 11.6 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Aspzincin_M35 PF14521.6 KIY71307.1 - 1.6e-43 148.8 7.8 1.6e-43 148.8 7.8 1.9 2 0 0 2 2 2 1 Lysine-specific metallo-endopeptidase HRXXH PF13933.6 KIY71307.1 - 0.0011 18.5 6.1 0.082 12.5 1.3 2.1 1 1 1 2 2 2 2 Putative peptidase family DUF3104 PF11302.8 KIY71307.1 - 0.029 14.1 0.4 1.8 8.3 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3104) Aspzincin_M35 PF14521.6 KIY71308.1 - 2.4e-43 148.1 2.4 2.4e-43 148.1 2.4 1.7 2 0 0 2 2 2 1 Lysine-specific metallo-endopeptidase GST_N_2 PF13409.6 KIY71310.1 - 2.6e-19 69.3 0.0 4.6e-19 68.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KIY71310.1 - 3.9e-19 68.8 0.0 8e-19 67.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KIY71310.1 - 1.7e-10 41.1 0.0 3.2e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KIY71310.1 - 4.2e-05 23.5 0.2 4.2e-05 23.5 0.2 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KIY71310.1 - 0.0034 17.6 0.0 0.0062 16.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KIY71310.1 - 0.013 16.1 0.0 0.022 15.3 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KIY71310.1 - 0.018 15.7 0.0 0.038 14.7 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain Glutaredoxin PF00462.24 KIY71310.1 - 0.17 12.1 0.0 0.33 11.2 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin zf-TRAF PF02176.18 KIY71311.1 - 0.062 14.0 1.5 0.14 12.8 1.5 1.6 1 0 0 1 1 1 0 TRAF-type zinc finger IBR PF01485.21 KIY71311.1 - 0.11 12.8 3.6 0.94 9.8 2.8 2.1 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain OrsD PF12013.8 KIY71311.1 - 0.13 12.7 4.5 1.6 9.2 0.6 2.1 1 1 1 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_4 PF13894.6 KIY71311.1 - 0.17 12.8 4.5 4.5 8.4 0.2 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-Nse PF11789.8 KIY71311.1 - 0.58 10.0 4.9 6.3 6.7 4.9 2.2 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Aspzincin_M35 PF14521.6 KIY71312.1 - 1.9e-16 60.9 0.6 1.9e-16 60.9 0.6 2.0 1 1 1 2 2 2 1 Lysine-specific metallo-endopeptidase SDA1 PF05285.12 KIY71315.1 - 0.024 14.1 0.5 0.026 13.9 0.5 1.2 1 0 0 1 1 1 0 SDA1 eIF2A PF08662.11 KIY71317.1 - 5.5e-78 261.3 0.0 2.8e-77 259.0 0.0 1.9 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 KIY71317.1 - 0.0015 19.3 0.1 0.69 10.9 0.1 3.9 4 0 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY71317.1 - 0.14 12.5 0.0 45 4.4 0.0 3.6 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KIY71317.1 - 0.53 10.3 3.7 56 3.8 0.0 3.8 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat HsbA PF12296.8 KIY71318.1 - 0.022 15.2 5.9 0.044 14.2 5.8 1.5 1 1 0 1 1 1 0 Hydrophobic surface binding protein A SSTK-IP PF15836.5 KIY71318.1 - 0.1 12.7 0.0 0.48 10.6 0.0 1.9 1 1 1 2 2 2 0 SSTK-interacting protein, TSSK6-activating co-chaperone protein ATG101 PF07855.12 KIY71318.1 - 0.13 12.2 0.0 0.2 11.6 0.0 1.5 1 1 0 1 1 1 0 Autophagy-related protein 101 Mito_carr PF00153.27 KIY71320.1 - 6.2e-29 99.8 3.0 1.2e-15 57.2 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein dCMP_cyt_deam_1 PF00383.23 KIY71321.1 - 1.3e-11 44.3 0.0 1.5e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 KIY71321.1 - 1.6e-05 25.1 0.0 2.1e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Med14 PF08638.11 KIY71322.1 - 0.014 14.8 0.1 0.026 13.9 0.1 1.5 1 1 0 1 1 1 0 Mediator complex subunit MED14 Pup PF05639.11 KIY71322.1 - 0.018 15.9 0.2 0.097 13.6 0.0 1.9 2 0 0 2 2 2 0 Pup-like protein MFS_1 PF07690.16 KIY71323.1 - 7.4e-14 51.4 40.2 1.1e-12 47.5 38.0 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily G0-G1_switch_2 PF15103.6 KIY71323.1 - 0.027 14.9 0.2 9.5 6.7 0.0 3.4 3 0 0 3 3 3 0 G0/G1 switch protein 2 YoqO PF14037.6 KIY71323.1 - 0.081 13.5 2.4 0.34 11.5 0.3 2.7 2 0 0 2 2 2 0 YoqO-like protein APP_E2 PF12925.7 KIY71324.1 - 0.044 13.5 0.5 0.065 12.9 0.5 1.2 1 0 0 1 1 1 0 E2 domain of amyloid precursor protein bMG5 PF17972.1 KIY71324.1 - 0.13 12.6 0.4 0.24 11.7 0.4 1.4 1 0 0 1 1 1 0 Bacterial Alpha-2-macroglobulin MG5 domain PIN_4 PF13638.6 KIY71325.1 - 6.1e-08 33.0 0.0 1.3e-07 31.9 0.0 1.6 1 0 0 1 1 1 1 PIN domain Pkinase PF00069.25 KIY71326.1 - 8.3e-19 68.0 0.0 1.1e-18 67.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY71326.1 - 4.2e-13 49.2 0.0 7.4e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KIY71326.1 - 5.3e-05 22.7 0.1 8.8e-05 21.9 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIY71326.1 - 0.028 14.3 0.1 0.051 13.5 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 KIY71326.1 - 0.17 11.5 0.2 0.27 10.8 0.2 1.3 1 0 0 1 1 1 0 RIO1 family Aldo_ket_red PF00248.21 KIY71327.1 - 3.3e-75 253.0 0.0 3.7e-75 252.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family OTU PF02338.19 KIY71328.1 - 3.7e-15 56.5 0.0 5.8e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 KIY71328.1 - 0.0067 15.9 0.0 2.5 7.5 0.0 2.2 2 0 0 2 2 2 2 Peptidase C65 Otubain MSP1_C PF07462.11 KIY71329.1 - 1.9 7.1 6.0 2.8 6.6 6.0 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Fungal_trans PF04082.18 KIY71330.1 - 3.5e-20 72.1 0.0 5.9e-20 71.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Striatin PF08232.12 KIY71330.1 - 0.00065 20.3 4.0 0.0012 19.5 4.0 1.4 1 0 0 1 1 1 1 Striatin family Lzipper-MIP1 PF14389.6 KIY71330.1 - 0.012 15.9 0.4 0.024 14.9 0.4 1.5 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 Zn_clus PF00172.18 KIY71330.1 - 0.012 15.7 12.8 0.022 14.9 12.8 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Dynamitin PF04912.14 KIY71330.1 - 0.019 14.3 0.2 0.029 13.7 0.2 1.1 1 0 0 1 1 1 0 Dynamitin Lar_restr_allev PF14354.6 KIY71330.1 - 0.25 11.8 4.0 0.54 10.7 4.0 1.5 1 0 0 1 1 1 0 Restriction alleviation protein Lar ATG16 PF08614.11 KIY71330.1 - 1 9.5 5.9 0.46 10.7 3.4 1.6 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Glyco_hydro_6 PF01341.17 KIY71331.1 - 1.6e-99 333.5 0.8 1.9e-99 333.3 0.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 DUF775 PF05603.12 KIY71332.1 - 4.6e-48 163.4 0.0 5.3e-48 163.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF775) Sod_Fe_C PF02777.18 KIY71333.1 - 9.9e-36 122.0 0.0 1.7e-35 121.2 0.0 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KIY71333.1 - 5.3e-31 106.9 3.4 5.4e-31 106.9 2.3 1.6 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Glyco_hydro_16 PF00722.21 KIY71336.1 - 1.5e-19 70.2 0.3 4e-19 68.7 0.2 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Fructosamin_kin PF03881.14 KIY71336.1 - 0.11 11.7 0.1 0.17 11.0 0.1 1.2 1 0 0 1 1 1 0 Fructosamine kinase ATPase_gene1 PF09527.10 KIY71336.1 - 0.41 10.9 3.8 0.56 10.4 0.4 2.2 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter CFEM PF05730.11 KIY71337.1 - 3.5e-05 23.8 8.4 5.9e-05 23.1 8.4 1.4 1 0 0 1 1 1 1 CFEM domain Velvet PF11754.8 KIY71338.1 - 1.5e-21 77.5 0.1 7e-13 49.1 0.0 2.1 1 1 1 2 2 2 2 Velvet factor FAM176 PF14851.6 KIY71338.1 - 0.066 12.9 0.1 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 FAM176 family HAUS2 PF15003.6 KIY71338.1 - 0.092 12.5 0.2 0.51 10.0 0.0 2.0 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 2 OppC_N PF12911.7 KIY71339.1 - 0.077 13.0 0.8 1.5 8.8 0.1 2.8 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C Cyt-b5 PF00173.28 KIY71340.1 - 3.2e-11 43.2 0.0 4.1e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain UCR_hinge PF02320.16 KIY71341.1 - 5.6e-25 87.3 8.2 5.6e-25 87.3 8.2 1.6 2 0 0 2 2 2 1 Ubiquinol-cytochrome C reductase hinge protein Sigma70_ner PF04546.13 KIY71341.1 - 0.0077 16.1 5.4 0.0085 16.0 5.4 1.1 1 0 0 1 1 1 1 Sigma-70, non-essential region DREPP PF05558.12 KIY71341.1 - 0.64 9.9 13.2 0.75 9.6 13.2 1.1 1 0 0 1 1 1 0 DREPP plasma membrane polypeptide Paf1 PF03985.13 KIY71341.1 - 1.5 7.7 10.6 1.7 7.6 10.6 1.1 1 0 0 1 1 1 0 Paf1 PTPRCAP PF15713.5 KIY71341.1 - 1.8 8.8 11.5 2.2 8.5 11.5 1.1 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Velvet PF11754.8 KIY71342.1 - 1.4e-20 74.3 0.0 2.2e-12 47.5 0.0 2.1 1 1 1 2 2 2 2 Velvet factor ERCC4 PF02732.15 KIY71343.1 - 6.2e-21 75.2 0.0 1.4e-20 74.1 0.0 1.6 1 0 0 1 1 1 1 ERCC4 domain zf-C2H2 PF00096.26 KIY71344.1 - 1.3e-06 28.5 11.3 0.00011 22.4 3.1 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIY71344.1 - 5.9e-05 23.6 9.1 0.0018 19.0 2.0 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KIY71344.1 - 0.00066 20.0 7.7 0.018 15.4 0.2 3.6 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 KIY71344.1 - 0.0073 16.3 0.7 0.0073 16.3 0.7 2.0 2 0 0 2 2 2 1 C2H2-type zinc finger zf-FCS PF06467.14 KIY71344.1 - 0.022 14.7 1.9 0.054 13.4 1.9 1.8 1 1 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif zf-C2H2_2 PF12756.7 KIY71344.1 - 1.2 9.5 3.8 0.72 10.2 0.5 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Plus-3 PF03126.18 KIY71345.1 - 2.2e-24 86.0 0.0 6.6e-24 84.5 0.0 1.9 1 0 0 1 1 1 1 Plus-3 domain Glucan_synthase PF02364.15 KIY71346.1 - 0 1299.3 0.0 0 1299.0 0.0 1.1 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 KIY71346.1 - 4.8e-42 143.3 0.1 1.3e-41 141.9 0.1 1.8 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Peptidase_M35 PF02102.15 KIY71347.1 - 2.6e-27 95.7 20.7 3.2e-27 95.3 20.7 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 KIY71347.1 - 1.3e-21 77.7 2.8 3.1e-21 76.4 2.8 1.7 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase HRXXH PF13933.6 KIY71347.1 - 5.4e-09 36.0 3.7 1.4e-08 34.6 3.7 1.6 1 1 0 1 1 1 1 Putative peptidase family YbbR PF07949.12 KIY71347.1 - 0.31 11.4 4.3 0.28 11.5 1.5 2.4 2 1 0 2 2 2 0 YbbR-like protein SWM_repeat PF13753.6 KIY71347.1 - 0.85 9.8 5.7 0.27 11.4 0.3 2.9 3 1 0 3 3 3 0 Putative flagellar system-associated repeat DUF4743 PF15916.5 KIY71348.1 - 2.3e-10 40.5 0.0 2.3e-07 30.8 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4743) NUDIX PF00293.28 KIY71348.1 - 0.00067 19.7 0.0 0.0014 18.7 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain Peroxidase_2 PF01328.17 KIY71349.1 - 2.4e-45 155.4 0.0 3.7e-45 154.8 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 Aldo_ket_red PF00248.21 KIY71350.1 - 1.4e-42 145.9 0.1 9.9e-42 143.1 0.1 1.8 1 1 0 1 1 1 1 Aldo/keto reductase family HAD_2 PF13419.6 KIY71351.1 - 5.5e-19 68.9 0.0 4.2e-18 66.0 0.0 2.0 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KIY71351.1 - 2.6e-15 57.3 0.0 3.9e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KIY71351.1 - 1.2e-06 28.5 0.7 7.6e-06 25.9 0.0 2.1 2 0 0 2 2 2 1 HAD-hyrolase-like HAD PF12710.7 KIY71351.1 - 0.00082 19.8 0.2 0.032 14.6 0.0 2.9 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase ADH_zinc_N PF00107.26 KIY71351.1 - 0.0018 18.3 0.1 0.0046 16.9 0.1 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PhoLip_ATPase_C PF16212.5 KIY71352.1 - 7.2 6.3 27.1 2.6 7.7 22.5 2.0 1 1 1 2 2 2 0 Phospholipid-translocating P-type ATPase C-terminal TPR_12 PF13424.6 KIY71353.1 - 2.4e-40 136.7 31.1 1.6e-12 47.5 0.8 6.8 6 1 1 7 7 6 5 Tetratricopeptide repeat TPR_10 PF13374.6 KIY71353.1 - 3.9e-39 131.5 34.1 1.4e-07 31.1 0.0 10.1 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_2 PF07719.17 KIY71353.1 - 3.4e-11 42.4 22.1 0.18 12.0 0.3 7.6 8 0 0 8 8 7 5 Tetratricopeptide repeat TPR_7 PF13176.6 KIY71353.1 - 8.6e-11 41.1 14.6 0.00097 19.0 0.3 6.7 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 KIY71353.1 - 1.6e-10 40.3 11.1 0.61 10.4 0.0 7.9 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_1 PF00515.28 KIY71353.1 - 9.2e-08 31.6 6.7 0.066 13.1 0.4 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat ANAPC5 PF12862.7 KIY71353.1 - 0.001 19.1 6.2 0.39 10.8 0.0 5.0 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 5 TniB PF05621.11 KIY71353.1 - 0.004 16.6 0.0 0.0089 15.5 0.0 1.5 1 0 0 1 1 1 1 Bacterial TniB protein AAA_22 PF13401.6 KIY71353.1 - 0.015 15.5 0.0 0.062 13.6 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KIY71353.1 - 0.017 15.2 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 KIY71353.1 - 0.033 14.4 0.0 0.13 12.5 0.0 2.0 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase MIT PF04212.18 KIY71353.1 - 0.048 13.7 6.1 0.49 10.5 0.2 4.4 4 1 1 5 5 5 0 MIT (microtubule interacting and transport) domain ATPase PF06745.13 KIY71353.1 - 0.15 11.4 0.1 0.4 10.0 0.0 1.7 2 0 0 2 2 2 0 KaiC TPR_14 PF13428.6 KIY71353.1 - 0.4 11.6 22.7 19 6.4 0.8 7.6 7 1 1 8 8 7 0 Tetratricopeptide repeat TPR_16 PF13432.6 KIY71353.1 - 0.49 11.1 25.7 0.31 11.7 2.0 5.3 4 2 0 4 4 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 KIY71353.1 - 6.3 7.4 19.1 3.8 8.1 0.5 5.3 4 2 1 6 6 6 0 Tetratricopeptide repeat FA_desaturase PF00487.24 KIY71354.1 - 2.4e-16 60.4 33.3 4.7e-16 59.4 33.3 1.4 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 KIY71354.1 - 1.6e-11 44.2 0.0 3.9e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Yip1 PF04893.17 KIY71355.1 - 5.5e-10 39.2 17.8 7.4e-10 38.8 17.5 1.4 1 1 0 1 1 1 1 Yip1 domain Prothymosin PF03247.14 KIY71356.1 - 8.2 6.9 13.6 11 6.5 0.7 2.2 2 0 0 2 2 2 0 Prothymosin/parathymosin family CNOT11 PF10155.9 KIY71357.1 - 4e-18 65.8 0.0 6.5e-18 65.1 0.0 1.3 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 11 ThiF PF00899.21 KIY71358.1 - 2.1e-43 148.5 0.0 9.1e-43 146.4 0.0 1.8 2 0 0 2 2 2 1 ThiF family Sacchrp_dh_NADP PF03435.18 KIY71358.1 - 0.0018 18.5 1.0 0.034 14.4 1.0 2.4 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 KIY71358.1 - 0.0079 16.6 0.1 0.017 15.5 0.1 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding 3HCDH_N PF02737.18 KIY71358.1 - 0.042 13.7 0.0 0.099 12.5 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.24 KIY71358.1 - 0.061 12.9 0.1 0.13 11.9 0.1 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.14 KIY71358.1 - 0.063 12.8 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.21 KIY71358.1 - 0.12 11.6 1.9 0.14 11.4 0.1 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.16 KIY71358.1 - 0.19 11.4 0.2 0.53 9.9 0.0 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Methyltransf_3 PF01596.17 KIY71359.1 - 3.7e-37 127.6 0.0 4.7e-37 127.2 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 KIY71359.1 - 2.7e-17 63.7 0.0 5.8e-17 62.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KIY71359.1 - 1.4e-07 31.5 0.0 1.8e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 KIY71359.1 - 6.5e-06 26.0 0.0 9.5e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIY71359.1 - 1.7e-05 25.5 0.0 3.4e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIY71359.1 - 0.00061 20.4 0.0 0.0014 19.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 KIY71359.1 - 0.0085 15.7 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_18 PF12847.7 KIY71359.1 - 0.013 15.5 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain F-box-like PF12937.7 KIY71361.1 - 4.1e-06 26.6 0.1 4.3e-05 23.3 0.0 2.9 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 KIY71361.1 - 0.00045 20.0 0.0 0.0026 17.6 0.0 2.4 1 0 0 1 1 1 1 F-box domain DUF3760 PF12586.8 KIY71361.1 - 0.0076 16.4 0.2 0.022 14.9 0.2 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3760) AKAP28 PF14469.6 KIY71361.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 28 kDa A-kinase anchor LRR_4 PF12799.7 KIY71361.1 - 0.14 12.6 14.3 9.5 6.8 1.5 4.9 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KIY71362.1 - 0.049 13.5 0.1 0.049 13.5 0.1 2.3 3 0 0 3 3 3 0 F-box-like zf-C3HC4_2 PF13923.6 KIY71363.1 - 0.00059 19.6 7.4 0.001 18.8 7.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FAM76 PF16046.5 KIY71363.1 - 0.0024 17.3 10.5 0.0024 17.3 10.5 2.1 1 1 1 2 2 2 1 FAM76 protein zf-RING_5 PF14634.6 KIY71363.1 - 0.0051 16.7 10.6 0.0082 16.1 10.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Pox_mRNA-cap PF03341.13 KIY71363.1 - 0.034 13.4 0.0 0.049 12.9 0.0 1.1 1 0 0 1 1 1 0 Poxvirus mRNA capping enzyme, small subunit zf-RING_UBOX PF13445.6 KIY71363.1 - 0.045 13.8 7.9 0.085 12.9 7.9 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.25 KIY71363.1 - 0.062 13.2 9.2 0.11 12.3 9.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Octopine_DH PF02317.17 KIY71363.1 - 0.11 12.6 0.4 0.21 11.7 0.4 1.5 1 0 0 1 1 1 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain DUF641 PF04859.12 KIY71363.1 - 0.88 9.9 12.3 2 8.7 3.4 2.6 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Hpt PF01627.23 KIY71363.1 - 2.2 8.6 9.0 6.5 7.1 0.7 2.9 3 0 0 3 3 3 0 Hpt domain AAA_11 PF13086.6 KIY71363.1 - 3.1 7.5 11.1 5 6.8 11.1 1.4 1 1 0 1 1 1 0 AAA domain DUF1664 PF07889.12 KIY71363.1 - 3.2 7.8 7.9 8.7 6.4 1.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) SGL PF08450.12 KIY71364.1 - 6.8e-71 238.7 0.0 8.1e-71 238.5 0.0 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 KIY71364.1 - 0.00028 21.0 0.0 0.0011 19.1 0.0 2.0 3 0 0 3 3 3 1 Arylesterase DUF5074 PF16819.5 KIY71364.1 - 0.09 12.8 0.0 2.2 8.4 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5074) Sin3a_C PF16879.5 KIY71366.1 - 4.8e-49 167.6 1.8 4.8e-49 167.6 1.8 5.1 4 2 1 5 5 5 2 C-terminal domain of Sin3a protein Sin3_corepress PF08295.12 KIY71366.1 - 1.5e-35 121.1 0.5 4.4e-35 119.7 0.5 1.8 1 0 0 1 1 1 1 Sin3 family co-repressor PAH PF02671.21 KIY71366.1 - 5.4e-26 90.5 2.0 7.7e-12 45.2 0.1 3.9 3 1 0 3 3 3 3 Paired amphipathic helix repeat Plasmodium_Vir PF05795.11 KIY71366.1 - 0.039 13.4 0.5 0.11 11.8 0.5 1.8 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Rrn6 PF10214.9 KIY71366.1 - 0.052 12.0 10.3 0.018 13.6 4.1 2.2 2 0 0 2 2 2 0 RNA polymerase I-specific transcription-initiation factor Pollen_allerg_1 PF01357.21 KIY71366.1 - 0.074 13.1 0.2 0.18 11.9 0.2 1.6 1 0 0 1 1 1 0 Pollen allergen DUF1682 PF07946.14 KIY71366.1 - 0.33 10.1 18.4 0.87 8.7 13.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1682) RR_TM4-6 PF06459.12 KIY71366.1 - 1.3 8.8 8.4 4.1 7.2 8.4 1.7 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 KIY71366.1 - 2.9 6.5 6.3 5.7 5.6 6.3 1.4 1 0 0 1 1 1 0 Presenilin Med3 PF11593.8 KIY71367.1 - 0.0069 15.6 1.5 0.013 14.7 1.5 1.4 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal Adeno_E3_CR2 PF02439.15 KIY71367.1 - 0.0079 15.9 0.8 0.017 14.9 0.8 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Protocadherin PF08374.11 KIY71367.1 - 0.087 12.8 0.1 0.087 12.8 0.1 3.0 4 1 0 4 4 4 0 Protocadherin SKG6 PF08693.10 KIY71367.1 - 0.41 10.1 4.5 0.59 9.6 3.4 1.9 1 1 0 1 1 1 0 Transmembrane alpha-helix domain Alpha_GJ PF03229.13 KIY71367.1 - 2.5 8.7 15.6 0.045 14.3 7.0 2.4 2 1 0 2 2 2 0 Alphavirus glycoprotein J Kelch_6 PF13964.6 KIY71368.1 - 0.11 12.8 0.3 0.47 10.8 0.1 2.0 2 0 0 2 2 2 0 Kelch motif SUIM_assoc PF16619.5 KIY71370.1 - 0.25 11.4 0.1 0.42 10.7 0.1 1.3 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 BCIP PF13862.6 KIY71371.1 - 2.1e-59 200.8 0.0 2.6e-59 200.5 0.0 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein PUF PF00806.19 KIY71372.1 - 2.2e-23 80.6 1.3 1.8e-07 30.4 0.0 6.2 7 0 0 7 7 7 4 Pumilio-family RNA binding repeat TLD PF07534.16 KIY71373.1 - 4e-29 101.6 0.0 6.2e-29 101.0 0.0 1.3 1 0 0 1 1 1 1 TLD EF1G PF00647.19 KIY71375.1 - 2.5e-41 140.1 0.1 6e-41 138.8 0.0 1.7 2 0 0 2 2 2 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 KIY71375.1 - 9.4e-11 41.8 0.7 3.7e-10 39.9 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KIY71375.1 - 2e-07 31.1 1.4 2.6e-07 30.7 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KIY71375.1 - 4.1e-07 30.3 0.0 8.1e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KIY71375.1 - 4.5e-05 23.7 0.0 0.00012 22.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KIY71375.1 - 0.0027 17.7 0.0 0.0072 16.3 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 KIY71375.1 - 0.02 14.7 0.1 0.061 13.1 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KIY71375.1 - 0.16 12.3 0.0 0.41 11.0 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain OAD_gamma PF04277.13 KIY71375.1 - 2.5 8.8 7.7 5 7.8 7.7 1.5 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Fungal_trans PF04082.18 KIY71376.1 - 9.6e-20 70.7 0.0 2e-19 69.7 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY71376.1 - 1.9e-07 31.1 11.0 3.1e-07 30.4 11.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Striatin PF08232.12 KIY71376.1 - 0.02 15.5 0.1 0.033 14.8 0.1 1.3 1 0 0 1 1 1 0 Striatin family Dynamitin PF04912.14 KIY71376.1 - 0.087 12.1 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 Dynamitin SelP_N PF04592.14 KIY71376.1 - 0.12 11.7 0.5 0.21 11.0 0.0 1.5 2 0 0 2 2 2 0 Selenoprotein P, N terminal region CPBP PF02517.16 KIY71377.1 - 1.4e-15 57.4 6.4 1.4e-15 57.4 6.4 3.4 4 0 0 4 4 4 1 CPBP intramembrane metalloprotease DUF1600 PF07667.11 KIY71377.1 - 0.041 14.1 3.8 1.8 8.8 0.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1600) AAA_13 PF13166.6 KIY71378.1 - 0.22 10.1 13.3 0.31 9.6 13.3 1.1 1 0 0 1 1 1 0 AAA domain ATP-synt_D PF01813.17 KIY71378.1 - 0.78 9.5 20.8 3 7.6 20.3 2.4 2 1 0 2 2 2 0 ATP synthase subunit D SPACA9 PF15120.6 KIY71378.1 - 1.1 9.0 7.0 2.9 7.7 7.0 1.7 1 0 0 1 1 1 0 Sperm acrosome-associated protein 9 DUF4407 PF14362.6 KIY71378.1 - 1.5 8.1 18.5 9.1 5.5 18.4 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) LMBR1 PF04791.16 KIY71378.1 - 2 7.2 5.7 2.8 6.8 5.7 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Fib_alpha PF08702.10 KIY71378.1 - 2.3 8.4 16.0 2 8.6 11.4 2.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Fez1 PF06818.15 KIY71378.1 - 3.3 8.1 22.2 6.7 7.1 19.2 2.3 1 1 1 2 2 2 0 Fez1 BLOC1_2 PF10046.9 KIY71378.1 - 4.6 7.6 13.8 4.6 7.6 2.0 2.9 2 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Herpes_UL25 PF01499.16 KIY71378.1 - 5.9 5.3 11.0 0.98 7.9 7.3 1.7 2 0 0 2 2 2 0 Herpesvirus UL25 family DUF4200 PF13863.6 KIY71378.1 - 6.8 7.1 37.2 2 8.8 8.7 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) Spc7 PF08317.11 KIY71378.1 - 9.4 5.0 31.4 1.3 7.8 11.1 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein F-box-like PF12937.7 KIY71379.1 - 4.7e-08 32.8 1.1 4.7e-08 32.8 1.1 2.1 2 0 0 2 2 2 1 F-box-like PSK_trans_fac PF07704.11 KIY71379.1 - 0.048 14.4 0.7 0.11 13.2 0.7 1.6 1 0 0 1 1 1 0 Rv0623-like transcription factor Asp PF00026.23 KIY71380.1 - 9.6e-34 117.2 0.4 9.2e-18 64.7 1.5 2.1 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIY71380.1 - 2.8e-06 27.7 2.6 7.3e-05 23.1 2.6 2.5 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KIY71380.1 - 0.01 16.4 2.8 0.14 12.8 0.8 2.9 2 1 0 2 2 2 0 Aspartyl protease Actino_peptide PF14408.6 KIY71381.1 - 0.018 15.1 0.6 0.057 13.5 0.1 2.0 2 0 0 2 2 2 0 Ribosomally synthesised peptide in actinomycetes Glyco_hydro_18 PF00704.28 KIY71383.1 - 8.8e-64 216.2 1.5 1.1e-63 215.8 1.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 GHL10 PF02638.15 KIY71383.1 - 0.0005 19.2 0.0 0.0011 18.1 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase-like 10 DUF4336 PF14234.6 KIY71384.1 - 8.1e-17 61.4 0.0 1e-09 38.1 0.0 2.8 2 1 0 2 2 2 2 Domain of unknown function (DUF4336) UCH PF00443.29 KIY71385.1 - 1.1e-40 139.8 0.0 1.5e-40 139.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KIY71385.1 - 3.7e-09 36.6 0.2 0.03 13.9 0.0 3.2 3 0 0 3 3 3 3 Ubiquitin carboxyl-terminal hydrolase F-box PF00646.33 KIY71386.1 - 1.6e-05 24.6 0.5 3.4e-05 23.6 0.5 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KIY71386.1 - 0.0054 16.6 0.3 0.011 15.6 0.3 1.6 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KIY71386.1 - 0.038 13.9 0.0 0.069 13.0 0.0 1.3 1 0 0 1 1 1 0 F-box F-box PF00646.33 KIY71387.1 - 7.4e-06 25.7 0.9 1.7e-05 24.5 0.9 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KIY71387.1 - 1.4e-05 24.9 1.1 2.6e-05 24.0 1.1 1.4 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KIY71387.1 - 0.0012 18.7 0.1 0.0023 17.8 0.1 1.4 1 0 0 1 1 1 1 F-box F-box PF00646.33 KIY71388.1 - 1.7e-05 24.5 0.4 4.3e-05 23.3 0.4 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KIY71388.1 - 4.8e-05 23.2 0.6 0.00011 22.1 0.6 1.6 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KIY71388.1 - 0.0085 16.0 0.1 0.021 14.7 0.1 1.6 1 0 0 1 1 1 1 F-box MauJ PF17419.2 KIY71388.1 - 0.058 12.9 0.0 0.092 12.2 0.0 1.2 1 0 0 1 1 1 0 Methylamine utilization protein MauJ F-box PF00646.33 KIY71389.1 - 3.4e-05 23.6 0.6 8.1e-05 22.4 0.6 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KIY71389.1 - 0.0025 17.7 0.4 0.0066 16.3 0.4 1.8 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KIY71389.1 - 0.031 14.2 0.1 0.072 13.0 0.1 1.6 1 0 0 1 1 1 0 F-box 3HCDH_RFF PF18321.1 KIY71389.1 - 0.058 13.8 0.0 0.16 12.5 0.0 1.7 1 0 0 1 1 1 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain dsrm PF00035.26 KIY71390.1 - 1.6e-05 25.6 0.0 1.7e-05 25.4 0.0 1.1 1 0 0 1 1 1 1 Double-stranded RNA binding motif SAD_SRA PF02182.17 KIY71391.1 - 5.9e-37 126.8 0.1 8.6e-37 126.2 0.1 1.2 1 0 0 1 1 1 1 SAD/SRA domain DUF563 PF04577.14 KIY71392.1 - 1.8e-17 64.2 0.0 2.2e-16 60.6 0.0 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF563) Aminotran_1_2 PF00155.21 KIY71393.1 - 1.7e-14 53.8 0.0 3.7e-14 52.7 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II VIT PF08487.10 KIY71394.1 - 1.5e-33 115.3 2.4 2.9e-33 114.4 2.4 1.5 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 KIY71394.1 - 1.3e-26 93.4 0.0 2.7e-26 92.4 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KIY71394.1 - 9e-13 48.8 0.0 2.2e-12 47.6 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KIY71394.1 - 1.6e-09 38.4 0.4 9.7e-09 35.8 0.0 2.2 2 0 0 2 2 2 1 von Willebrand factor type A domain VIT_2 PF13757.6 KIY71394.1 - 3.1e-07 30.2 0.0 6.4e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_CoxE PF05762.14 KIY71394.1 - 4.4e-06 26.2 0.1 8.6e-06 25.3 0.1 1.4 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein Hexokinase_1 PF00349.21 KIY71394.1 - 0.13 12.1 0.1 0.28 11.1 0.1 1.5 1 0 0 1 1 1 0 Hexokinase Methyltransf_16 PF10294.9 KIY71397.1 - 5.2e-21 75.1 0.0 7.7e-21 74.6 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 KIY71397.1 - 2.6e-09 37.6 0.0 5.5e-09 36.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIY71397.1 - 2.9e-08 33.6 0.0 4.6e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIY71397.1 - 3.2e-07 31.0 0.0 5.5e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KIY71397.1 - 3.2e-06 26.8 0.0 6.6e-06 25.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 KIY71397.1 - 4.4e-06 26.3 0.0 6.2e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 KIY71397.1 - 1.3e-05 25.7 0.0 2.4e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 KIY71397.1 - 3.4e-05 23.7 0.0 5.2e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_23 PF13489.6 KIY71397.1 - 0.00016 21.5 0.0 0.00027 20.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KIY71397.1 - 0.0041 16.9 0.0 0.0059 16.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.7 KIY71397.1 - 0.2 11.6 0.0 0.32 10.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain SKN1 PF03935.15 KIY71399.1 - 4.1e-191 635.7 1.0 5.2e-191 635.4 1.0 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) DUF4719 PF15843.5 KIY71399.1 - 0.086 12.9 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4719) EamA PF00892.20 KIY71400.1 - 2e-20 73.4 28.5 8.2e-12 45.5 8.5 2.2 2 0 0 2 2 2 2 EamA-like transporter family Gemini_AC4_5_2 PF08464.10 KIY71400.1 - 0.036 14.0 0.9 0.3 11.1 0.2 2.6 3 0 0 3 3 3 0 Geminivirus AC4/5 conserved region DAO PF01266.24 KIY71401.1 - 2.7e-28 99.6 0.1 3.5e-28 99.2 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIY71401.1 - 9.9e-06 25.0 0.0 2.3e-05 23.8 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIY71401.1 - 1.2e-05 25.5 0.1 9.5e-05 22.6 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 KIY71401.1 - 1.2e-05 25.6 0.0 2.3e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Pyr_redox PF00070.27 KIY71401.1 - 0.00079 19.9 0.9 0.0026 18.3 0.3 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KIY71401.1 - 0.0013 18.1 0.0 0.0024 17.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 KIY71401.1 - 0.0042 16.2 0.2 0.0074 15.4 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 KIY71401.1 - 0.016 14.3 0.2 0.023 13.8 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 KIY71401.1 - 0.034 13.5 0.1 0.059 12.6 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 KIY71401.1 - 0.042 13.1 0.0 0.074 12.3 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KIY71401.1 - 0.062 12.9 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_oxidored PF12831.7 KIY71401.1 - 0.14 11.5 0.9 0.69 9.2 0.5 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase RPN1_RPN2_N PF17781.1 KIY71402.1 - 3.3e-109 365.0 0.0 5.3e-109 364.3 0.0 1.3 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 KIY71402.1 - 2.7e-29 101.0 0.0 5e-29 100.1 0.0 1.5 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 KIY71402.1 - 2e-22 78.4 21.0 2.7e-05 24.4 0.1 8.9 9 0 0 9 9 9 5 Proteasome/cyclosome repeat HEAT_2 PF13646.6 KIY71402.1 - 3.1e-05 24.3 0.2 1.6 9.1 0.0 4.8 5 1 1 6 6 6 1 HEAT repeats DUF1039 PF06287.11 KIY71402.1 - 0.074 13.5 2.8 0.74 10.3 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF1039) SPG4 PF17325.2 KIY71402.1 - 0.19 12.8 6.9 1.4 10.0 0.2 2.4 2 0 0 2 2 2 0 Stationary phase protein 4 RLL PF10036.9 KIY71402.1 - 0.43 10.4 5.4 0.79 9.5 0.6 2.3 2 0 0 2 2 2 0 RNA transcription, translation and transport factor protein CPSF100_C PF13299.6 KIY71402.1 - 6.2 7.0 9.8 2.4 8.3 0.6 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal FAM176 PF14851.6 KIY71402.1 - 7.6 6.2 12.3 4.9 6.8 2.5 2.3 2 0 0 2 2 2 0 FAM176 family Mito_carr PF00153.27 KIY71403.1 - 7e-56 186.1 3.9 8.7e-21 73.7 0.0 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF4413 PF14372.6 KIY71405.1 - 0.0085 16.4 0.1 0.025 15.0 0.0 1.9 2 1 0 2 2 2 1 Domain of unknown function (DUF4413) LON_substr_bdg PF02190.16 KIY71406.1 - 1.2e-19 71.1 0.0 1.7e-19 70.6 0.0 1.2 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_2 PF13923.6 KIY71406.1 - 9e-11 41.4 14.0 9e-11 41.4 14.0 2.9 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KIY71406.1 - 2.2e-08 34.0 23.2 5.6e-07 29.5 11.5 2.8 2 0 0 2 2 2 2 RING-type zinc-finger zf-RING_2 PF13639.6 KIY71406.1 - 1.4e-07 31.7 11.7 1.4e-07 31.7 11.7 2.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 KIY71406.1 - 1.4e-07 31.3 7.3 1.4e-07 31.3 7.3 2.7 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIY71406.1 - 1.3e-06 28.1 12.5 1.3e-06 28.1 12.5 2.7 3 0 0 3 3 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIY71406.1 - 2e-05 24.5 11.1 2e-05 24.5 11.1 2.9 3 0 0 3 3 3 1 zinc-RING finger domain zf-RING_10 PF16685.5 KIY71406.1 - 3.2e-05 24.0 7.2 3.2e-05 24.0 7.2 2.7 3 0 0 3 3 3 1 zinc RING finger of MSL2 Prok-RING_4 PF14447.6 KIY71406.1 - 0.00016 21.4 9.1 0.00016 21.4 9.1 3.2 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KIY71406.1 - 0.0012 18.9 12.9 0.0012 18.9 12.9 3.0 4 0 0 4 4 4 2 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 KIY71406.1 - 0.0054 16.6 14.7 0.027 14.3 3.4 2.4 2 0 0 2 2 2 2 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 KIY71406.1 - 0.0082 16.4 10.2 0.0082 16.4 10.2 2.3 2 2 0 2 2 2 1 RING-H2 zinc finger domain U-box PF04564.15 KIY71406.1 - 0.031 14.4 0.1 0.06 13.5 0.1 1.4 1 0 0 1 1 1 0 U-box domain DUF1889 PF08986.10 KIY71408.1 - 0.13 12.7 0.0 0.19 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1889) Pkinase PF00069.25 KIY71409.1 - 4.6e-63 213.0 0.5 1.2e-43 149.4 0.1 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIY71409.1 - 3.3e-29 102.0 0.5 1.3e-21 77.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 KIY71409.1 - 1.4e-07 30.8 0.0 1.9e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KIY71409.1 - 0.00016 21.1 0.3 0.0008 18.8 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIY71409.1 - 0.00046 20.2 0.1 0.025 14.5 0.1 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KIY71409.1 - 0.0033 16.8 0.3 0.017 14.4 0.0 2.3 2 1 1 3 3 3 1 Kinase-like Pkinase_fungal PF17667.1 KIY71409.1 - 0.0094 14.8 0.0 0.018 13.8 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 KIY71409.1 - 0.017 14.7 0.1 0.036 13.7 0.1 1.4 1 0 0 1 1 1 0 RIO1 family Pox_ser-thr_kin PF05445.11 KIY71409.1 - 0.019 13.9 0.0 0.035 13.1 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Seadorna_VP7 PF07387.11 KIY71409.1 - 0.021 13.9 0.1 0.037 13.1 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_C PF00433.24 KIY71409.1 - 0.047 14.4 0.1 0.38 11.5 0.1 2.3 2 0 0 2 2 2 0 Protein kinase C terminal domain NUFIP1 PF10453.9 KIY71409.1 - 0.11 12.4 0.1 0.3 11.0 0.1 1.7 1 0 0 1 1 1 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) RasGAP_C PF03836.15 KIY71410.1 - 3.1e-35 121.3 0.5 3.1e-35 121.3 0.5 2.4 2 0 0 2 2 2 1 RasGAP C-terminus RasGAP PF00616.19 KIY71410.1 - 2e-34 119.2 0.1 4.8e-34 117.9 0.1 1.7 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase IQ PF00612.27 KIY71410.1 - 2.5e-16 57.9 62.3 0.013 15.2 0.8 13.3 13 0 0 13 13 13 9 IQ calmodulin-binding motif CH PF00307.31 KIY71410.1 - 5.1e-12 45.9 0.0 1.5e-11 44.4 0.0 1.9 1 0 0 1 1 1 1 Calponin homology (CH) domain Sipho_Gp157 PF05565.11 KIY71410.1 - 0.002 18.2 0.2 0.002 18.2 0.2 3.1 3 0 0 3 3 3 1 Siphovirus Gp157 G6PD_C PF02781.16 KIY71411.1 - 5.1e-112 373.8 0.0 7e-112 373.3 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 KIY71411.1 - 2.4e-59 200.9 0.0 3.8e-59 200.3 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain FmiP_Thoc5 PF09766.9 KIY71412.1 - 7.7e-31 107.7 10.0 8.7e-31 107.5 10.0 1.0 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 Mod_r PF07200.13 KIY71412.1 - 0.065 13.3 8.8 0.71 10.0 3.3 2.2 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein FATC PF02260.20 KIY71412.1 - 0.23 11.3 0.4 0.48 10.3 0.4 1.5 1 0 0 1 1 1 0 FATC domain YtzH PF14165.6 KIY71412.1 - 0.68 10.4 5.3 0.18 12.2 1.5 2.0 2 1 0 2 2 2 0 YtzH-like protein UQ_con PF00179.26 KIY71413.1 - 3.6e-38 130.4 0.1 4.6e-38 130.0 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KIY71413.1 - 0.12 12.6 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 RWD domain CbtB PF09489.10 KIY71414.1 - 0.042 13.9 1.0 0.38 10.9 0.2 2.1 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtB) S_4TM PF18159.1 KIY71415.1 - 5.2 6.3 5.5 9 5.5 0.1 2.1 2 0 0 2 2 2 0 SMODS-associating 4TM effector domain SLAC1 PF03595.17 KIY71416.1 - 0.1 11.8 8.4 0.17 11.1 8.4 1.3 1 0 0 1 1 1 0 Voltage-dependent anion channel MARVEL PF01284.23 KIY71416.1 - 0.11 12.6 15.7 0.4 10.7 15.8 1.8 1 1 0 1 1 1 0 Membrane-associating domain DUF2231 PF09990.9 KIY71416.1 - 0.23 11.9 5.4 0.83 10.1 0.4 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2231) AMP-binding PF00501.28 KIY71417.1 - 8.7e-42 143.2 0.0 1.2e-41 142.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KIY71417.1 - 1e-05 25.3 3.4 2.4e-05 24.2 3.4 1.7 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 KIY71417.1 - 0.0011 19.9 0.0 0.0026 18.7 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Metallophos PF00149.28 KIY71419.1 - 6.9e-10 39.8 0.9 1.3e-09 38.9 0.9 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase RFX_DNA_binding PF02257.15 KIY71420.1 - 2.9e-28 98.3 0.1 5.3e-28 97.5 0.1 1.4 1 0 0 1 1 1 1 RFX DNA-binding domain NuDC PF16273.5 KIY71420.1 - 0.026 15.1 1.4 0.053 14.1 1.4 1.5 1 0 0 1 1 1 0 Nuclear distribution C domain ABC_tran_CTD PF16326.5 KIY71421.1 - 0.0015 18.7 0.8 0.0015 18.7 0.8 6.6 6 1 2 8 8 8 2 ABC transporter C-terminal domain Golgin_A5 PF09787.9 KIY71421.1 - 0.04 13.4 27.7 0.68 9.3 12.2 2.8 1 1 0 2 2 2 0 Golgin subfamily A member 5 FapA PF03961.13 KIY71421.1 - 0.22 10.1 18.2 0.15 10.6 7.1 2.4 1 1 2 3 3 3 0 Flagellar Assembly Protein A JIP_LZII PF16471.5 KIY71421.1 - 0.33 11.2 5.0 8.8 6.6 0.3 4.5 3 0 0 3 3 3 0 JNK-interacting protein leucine zipper II Baculo_PEP_C PF04513.12 KIY71421.1 - 0.38 10.8 3.3 6.7 6.7 0.6 3.3 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus YabA PF06156.13 KIY71421.1 - 0.79 10.4 10.5 1.1 9.9 0.3 3.9 1 1 1 3 3 3 0 Initiation control protein YabA NPV_P10 PF05531.12 KIY71421.1 - 2.4 8.7 14.5 3.8 8.0 0.2 4.7 4 2 0 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF5517 PF17639.2 KIY71421.1 - 3.2 8.1 8.4 3.4 8.0 0.2 3.4 3 0 0 3 3 3 0 Family of unknown function (DUF5517) Ribosomal_L7Ae PF01248.26 KIY71422.1 - 2.5e-23 81.6 1.7 3.2e-23 81.3 0.5 1.8 2 0 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Cupin_8 PF13621.6 KIY71423.1 - 4.2e-52 177.4 0.0 5.8e-52 176.9 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 KIY71423.1 - 9.9e-05 22.7 0.0 0.00052 20.4 0.0 2.1 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 KIY71423.1 - 0.0088 15.7 0.1 0.34 10.6 0.0 2.3 2 0 0 2 2 2 1 Cupin domain Cupin_4 PF08007.12 KIY71423.1 - 0.026 14.0 0.0 0.065 12.7 0.0 1.6 1 0 0 1 1 1 0 Cupin superfamily protein DUF455 PF04305.14 KIY71424.1 - 2.9e-90 302.2 0.0 3.6e-90 301.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF455) Rieske PF00355.26 KIY71424.1 - 1.1e-05 25.3 0.0 2.3e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 KIY71424.1 - 0.002 18.1 0.0 0.0039 17.1 0.0 1.4 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain UvdE PF03851.14 KIY71426.1 - 3.1e-89 298.9 0.0 4.1e-89 298.5 0.0 1.2 1 0 0 1 1 1 1 UV-endonuclease UvdE Fasciclin PF02469.22 KIY71427.1 - 5.2e-30 104.3 4.3 2.6e-18 66.5 1.1 2.5 1 1 0 2 2 2 2 Fasciclin domain Vps16_N PF04841.13 KIY71427.1 - 0.13 11.0 0.0 0.2 10.4 0.0 1.3 1 0 0 1 1 1 0 Vps16, N-terminal region zf-CCHC PF00098.23 KIY71428.1 - 6.7e-09 35.4 31.7 0.00063 19.7 5.2 4.5 4 0 0 4 4 4 3 Zinc knuckle zf-CCHC_3 PF13917.6 KIY71428.1 - 0.00021 21.2 24.8 0.0068 16.3 4.0 4.5 3 1 1 4 4 4 3 Zinc knuckle His_Phos_2 PF00328.22 KIY71429.1 - 7.1e-88 295.5 0.0 1e-87 295.0 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 KIY71429.1 - 6.6e-38 128.8 0.1 1.7e-37 127.4 0.1 1.8 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 KIY71429.1 - 5.5e-05 22.9 0.0 9.7e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 RimK-like ATP-grasp domain UQ_con PF00179.26 KIY71430.1 - 7.9e-18 64.5 0.2 1.1e-17 64.1 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KIY71430.1 - 0.18 12.1 0.1 0.22 11.8 0.0 1.3 1 1 0 1 1 1 0 RWD domain MFS_1 PF07690.16 KIY71431.1 - 5.4e-35 120.9 17.4 5.4e-35 120.9 17.4 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Phage_holin_5_2 PF16079.5 KIY71431.1 - 0.02 15.2 0.2 0.02 15.2 0.2 4.0 4 2 2 6 6 6 0 Phage holin family Hol44, in holin superfamily V PepSY_TM PF03929.16 KIY71432.1 - 0.02 14.6 0.1 0.024 14.3 0.1 1.1 1 0 0 1 1 1 0 PepSY-associated TM region Ribophorin_I PF04597.14 KIY71433.1 - 6.1e-128 427.8 1.6 6.9e-128 427.6 1.6 1.0 1 0 0 1 1 1 1 Ribophorin I Ribosomal_L22 PF00237.19 KIY71434.1 - 5.4e-22 78.0 0.7 7.1e-22 77.6 0.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e HxlR PF01638.17 KIY71434.1 - 0.01 15.7 0.2 3.4 7.6 0.0 2.2 2 0 0 2 2 2 0 HxlR-like helix-turn-helix 5-nucleotidase PF06189.12 KIY71434.1 - 0.017 14.1 0.1 0.028 13.4 0.1 1.3 1 0 0 1 1 1 0 5'-nucleotidase PUB_1 PF18486.1 KIY71434.1 - 0.032 14.1 0.0 0.093 12.6 0.0 1.7 2 0 0 2 2 2 0 PNGase/UBA- or UBX-containing domain Yos1 PF08571.10 KIY71435.1 - 5.5e-33 113.1 0.5 6.5e-33 112.8 0.5 1.1 1 0 0 1 1 1 1 Yos1-like Opy2 PF09463.10 KIY71436.1 - 4.3e-06 26.9 17.6 7e-06 26.3 17.6 1.4 1 0 0 1 1 1 1 Opy2 protein Phage_holin_3_6 PF07332.11 KIY71436.1 - 0.16 12.0 0.1 0.27 11.3 0.1 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III EphA2_TM PF14575.6 KIY71436.1 - 0.17 12.8 0.0 0.37 11.7 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain ABC_tran PF00005.27 KIY71437.1 - 6.3e-16 59.1 0.0 2e-15 57.5 0.0 1.8 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KIY71437.1 - 3.4e-09 37.0 4.0 0.0003 20.7 0.1 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KIY71437.1 - 0.00016 21.3 0.1 0.00038 20.1 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 KIY71437.1 - 0.0011 18.4 0.1 0.68 9.3 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KIY71437.1 - 0.0022 18.5 0.0 0.0039 17.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 KIY71437.1 - 0.0031 17.1 0.9 0.018 14.6 0.1 2.2 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KIY71437.1 - 0.0039 17.1 0.1 0.0059 16.5 0.1 1.2 1 0 0 1 1 1 1 RsgA GTPase AAA_15 PF13175.6 KIY71437.1 - 0.043 13.5 0.1 0.06 13.1 0.1 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_16 PF13191.6 KIY71437.1 - 0.086 13.2 0.3 0.19 12.1 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain MMR_HSR1 PF01926.23 KIY71437.1 - 0.088 12.9 0.3 0.23 11.6 0.3 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase Arf PF00025.21 KIY71437.1 - 0.11 12.0 0.1 0.44 10.0 0.0 2.0 3 0 0 3 3 3 0 ADP-ribosylation factor family AAA_28 PF13521.6 KIY71437.1 - 0.13 12.5 0.3 0.34 11.2 0.1 1.8 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KIY71437.1 - 0.15 12.3 1.8 1.8 8.8 0.1 2.7 3 0 0 3 3 3 0 AAA domain Rhodanese PF00581.20 KIY71439.1 - 7.9e-06 26.4 0.0 1.3e-05 25.6 0.0 1.4 1 1 0 1 1 1 1 Rhodanese-like domain DUF1682 PF07946.14 KIY71440.1 - 1.3e-89 300.6 0.3 1.5e-89 300.4 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) DUF612 PF04747.12 KIY71440.1 - 0.00067 18.9 10.4 0.0019 17.4 9.5 1.9 2 0 0 2 2 2 1 Protein of unknown function, DUF612 DUF3818 PF12825.7 KIY71442.1 - 6.4e-130 433.1 0.2 1.1e-129 432.4 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 KIY71442.1 - 2.2e-34 118.3 0.1 5.9e-34 116.9 0.1 1.8 1 0 0 1 1 1 1 PX-associated PX PF00787.24 KIY71442.1 - 3.7e-10 39.8 0.2 2e-09 37.4 0.0 2.4 2 0 0 2 2 2 1 PX domain Hormone_1 PF00103.20 KIY71442.1 - 0.18 11.6 0.0 0.46 10.2 0.0 1.6 1 0 0 1 1 1 0 Somatotropin hormone family Apt1 PF10351.9 KIY71442.1 - 1.1 8.0 6.7 4.2 6.1 6.7 1.9 1 0 0 1 1 1 0 Golgi-body localisation protein domain CDC45 PF02724.14 KIY71442.1 - 1.3 7.2 5.2 2.3 6.4 5.2 1.3 1 0 0 1 1 1 0 CDC45-like protein Cyclin_N PF00134.23 KIY71443.1 - 7e-37 126.0 0.7 1.1e-36 125.3 0.1 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KIY71443.1 - 2e-08 34.4 0.2 4.7e-08 33.1 0.2 1.7 1 1 0 1 1 1 1 Cyclin, C-terminal domain Tnp_DNA_bind PF14706.6 KIY71443.1 - 0.16 11.8 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 Transposase DNA-binding zf-RING_2 PF13639.6 KIY71444.1 - 0.00085 19.6 9.6 0.0018 18.5 9.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KIY71444.1 - 0.032 14.1 7.5 0.074 12.9 7.5 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Dscam_C PF12355.8 KIY71444.1 - 0.075 14.0 4.6 0.16 12.9 4.6 1.5 1 0 0 1 1 1 0 Down syndrome cell adhesion molecule C terminal DUF5321 PF17254.2 KIY71445.1 - 6.9e-07 28.8 0.1 9.8e-07 28.3 0.1 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5321) HSP90 PF00183.18 KIY71447.1 - 1.3e-136 456.5 0.0 1.3e-136 456.5 0.0 2.3 2 0 0 2 2 2 1 Hsp90 protein FF PF01846.19 KIY71447.1 - 3.7e-29 100.7 12.3 7.4e-08 32.4 0.0 6.2 6 0 0 6 6 6 5 FF domain HATPase_c_3 PF13589.6 KIY71447.1 - 3.2e-10 40.0 0.0 1e-09 38.3 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KIY71447.1 - 1.6e-08 35.0 0.0 4.1e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase WW PF00397.26 KIY71447.1 - 1.5e-05 25.0 6.3 0.0082 16.2 2.9 2.8 2 0 0 2 2 2 2 WW domain RhoGAP-FF1 PF16512.5 KIY71447.1 - 0.0044 17.7 7.7 0.95 10.2 0.9 3.7 3 0 0 3 3 3 2 p190-A and -B Rho GAPs FF domain Ery_res_leader1 PF08051.11 KIY71447.1 - 0.13 12.3 0.2 1.3 9.4 0.0 2.6 2 0 0 2 2 2 0 Erythromycin resistance leader peptide MEKHLA PF08670.11 KIY71448.1 - 0.23 11.4 0.3 0.46 10.4 0.3 1.4 1 0 0 1 1 1 0 MEKHLA domain ChaC PF04752.12 KIY71449.1 - 6.7e-52 176.1 0.0 7.6e-52 175.9 0.0 1.0 1 0 0 1 1 1 1 ChaC-like protein DEAD PF00270.29 KIY71450.1 - 2.1e-41 141.6 0.8 3.1e-41 141.1 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF4217 PF13959.6 KIY71450.1 - 1.1e-20 73.5 0.4 2.5e-20 72.5 0.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.31 KIY71450.1 - 2.4e-19 69.7 0.0 1.1e-18 67.6 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIY71450.1 - 7.5e-06 26.1 0.8 3.8e-05 23.8 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SBF_like PF13593.6 KIY71450.1 - 0.034 13.5 0.0 0.045 13.0 0.0 1.1 1 0 0 1 1 1 0 SBF-like CPA transporter family (DUF4137) UvrD-helicase PF00580.21 KIY71450.1 - 0.066 12.7 7.8 0.82 9.1 0.0 2.3 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain LMBR1 PF04791.16 KIY71450.1 - 0.19 10.6 4.3 0.28 10.0 4.3 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Dermcidin PF15291.6 KIY71450.1 - 1.1 9.8 4.8 3.4 8.3 4.8 1.8 1 0 0 1 1 1 0 Dermcidin, antibiotic peptide AAA_22 PF13401.6 KIY71451.1 - 2.5e-05 24.6 0.0 6.3e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KIY71451.1 - 9.4e-05 22.8 0.2 0.00077 19.9 0.2 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KIY71451.1 - 0.00011 22.2 0.0 0.0016 18.4 0.0 2.2 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_16 PF13191.6 KIY71451.1 - 0.0029 18.0 0.0 0.0069 16.8 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain T2SSE PF00437.20 KIY71451.1 - 0.012 14.7 0.2 0.028 13.5 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_18 PF13238.6 KIY71451.1 - 0.039 14.5 0.0 0.095 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KIY71451.1 - 0.077 13.0 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 KIY71451.1 - 0.12 12.0 0.0 0.3 10.8 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein ATPase_2 PF01637.18 KIY71451.1 - 0.17 11.8 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_29 PF13555.6 KIY71451.1 - 0.19 11.5 0.0 0.39 10.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain HLH PF00010.26 KIY71452.1 - 1.6e-10 40.8 0.2 3.5e-10 39.7 0.2 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain TFIIF_alpha PF05793.12 KIY71453.1 - 4.4e-05 22.3 66.7 0.32 9.6 0.0 5.0 2 2 1 3 3 3 2 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Polysacc_deac_1 PF01522.21 KIY71454.1 - 5.3e-23 81.3 0.0 1.1e-22 80.2 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 KIY71454.1 - 0.012 15.3 0.0 0.022 14.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) F-box-like PF12937.7 KIY71455.1 - 5.6e-11 42.2 0.0 1.7e-10 40.6 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY71455.1 - 0.024 14.5 5.8 0.11 12.4 3.5 2.9 2 1 0 2 2 2 0 F-box domain LRR_4 PF12799.7 KIY71455.1 - 0.27 11.7 2.1 8.4 7.0 0.0 3.5 2 2 3 5 5 5 0 Leucine Rich repeats (2 copies) PPR_2 PF13041.6 KIY71456.1 - 8.8e-17 61.0 3.9 6.4e-11 42.3 0.0 4.7 6 0 0 6 6 6 2 PPR repeat family PPR PF01535.20 KIY71456.1 - 3.1e-06 27.1 0.3 0.15 12.3 0.0 6.1 7 0 0 7 7 7 1 PPR repeat PPR_3 PF13812.6 KIY71456.1 - 0.00019 21.5 0.0 9 6.5 0.0 4.0 4 0 0 4 4 4 2 Pentatricopeptide repeat domain COX5A PF02284.16 KIY71456.1 - 0.0081 16.1 0.2 0.066 13.2 0.0 2.4 2 0 0 2 2 2 1 Cytochrome c oxidase subunit Va PPR_long PF17177.4 KIY71456.1 - 0.015 14.7 0.1 1.3 8.4 0.0 2.9 3 0 0 3 3 3 0 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 KIY71456.1 - 0.093 12.4 0.0 8.3 6.2 0.0 3.4 4 0 0 4 4 4 0 PPR repeat NAD_binding_4 PF07993.12 KIY71458.1 - 5.4e-19 68.4 0.3 1.9e-18 66.6 0.3 1.6 1 1 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 KIY71458.1 - 9.9e-08 31.7 0.0 1.4e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Arm_2 PF04826.13 KIY71458.1 - 0.031 13.7 0.3 0.045 13.2 0.3 1.1 1 0 0 1 1 1 0 Armadillo-like EF-hand_7 PF13499.6 KIY71459.1 - 1.8e-26 92.4 8.7 7.6e-18 64.7 1.5 3.1 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KIY71459.1 - 3.1e-24 82.7 11.0 6.3e-08 31.6 0.1 5.2 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.6 KIY71459.1 - 7.3e-22 75.4 7.8 1.6e-06 27.5 0.1 5.4 5 1 0 5 5 5 3 EF-hand domain EF-hand_8 PF13833.6 KIY71459.1 - 1.4e-12 47.2 9.3 2e-06 27.6 0.2 3.9 3 2 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 KIY71459.1 - 6.7e-12 44.3 9.8 0.00077 18.8 0.4 4.6 5 0 0 5 5 5 3 EF hand EF-hand_4 PF12763.7 KIY71459.1 - 1.4e-05 24.9 6.4 0.45 10.5 0.1 4.0 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KIY71459.1 - 8.7e-05 22.8 4.2 0.13 12.6 0.7 3.4 2 2 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 KIY71459.1 - 0.0074 16.6 2.4 2.2 8.7 0.0 3.5 2 1 1 3 3 3 1 EF-hand domain Pan3_PK PF18101.1 KIY71459.1 - 0.036 14.0 1.1 0.041 13.9 0.2 1.6 2 0 0 2 2 2 0 Pan3 Pseudokinase domain S10_plectin PF03501.15 KIY71459.1 - 0.037 14.1 0.0 0.058 13.5 0.0 1.4 1 0 0 1 1 1 0 Plectin/S10 domain EF-hand_2 PF09068.11 KIY71459.1 - 0.054 13.6 0.1 5.1 7.3 0.0 2.9 3 0 0 3 3 3 0 EF hand Caleosin PF05042.13 KIY71459.1 - 0.088 12.7 3.9 8.5 6.3 0.0 3.4 2 1 2 4 4 4 0 Caleosin related protein ANAPC4_WD40 PF12894.7 KIY71461.1 - 0.00023 21.4 0.0 0.099 13.0 0.0 2.7 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KIY71461.1 - 0.0017 19.1 0.0 0.8 10.7 0.0 3.0 2 0 0 2 2 2 2 WD domain, G-beta repeat DUF1513 PF07433.11 KIY71461.1 - 0.029 13.5 0.0 0.048 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1513) Cu-oxidase PF00394.22 KIY71462.1 - 5e-48 163.2 0.2 1.8e-45 154.9 0.1 3.0 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 KIY71462.1 - 1.2e-39 135.2 2.3 7.3e-36 122.9 0.0 3.2 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KIY71462.1 - 1.7e-32 111.9 2.1 2.2e-31 108.3 1.0 2.8 3 0 0 3 3 3 1 Multicopper oxidase Hjc PF01870.18 KIY71462.1 - 0.2 11.6 0.0 6.6 6.8 0.0 2.3 2 0 0 2 2 2 0 Archaeal holliday junction resolvase (hjc) ATE_C PF04377.15 KIY71463.1 - 4e-47 160.2 1.3 7.4e-47 159.3 1.3 1.5 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 KIY71463.1 - 3.4e-24 85.0 5.0 6.2e-24 84.2 5.0 1.4 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus Mito_carr PF00153.27 KIY71464.1 - 1.2e-49 166.2 3.9 1.7e-15 56.7 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PrcB_C PF14343.6 KIY71464.1 - 0.1 12.8 0.0 8 6.7 0.0 2.4 2 0 0 2 2 2 0 PrcB C-terminal UQ_con PF00179.26 KIY71465.1 - 4.8e-22 78.1 0.0 8.6e-22 77.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme IBR PF01485.21 KIY71465.1 - 0.0023 18.1 4.1 0.0053 16.9 4.1 1.6 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain UBA PF00627.31 KIY71465.1 - 0.026 14.4 0.8 0.066 13.1 0.8 1.7 1 0 0 1 1 1 0 UBA/TS-N domain GILT PF03227.16 KIY71466.1 - 1.1e-12 48.1 0.1 2.5e-12 47.0 0.0 1.6 2 0 0 2 2 2 1 Gamma interferon inducible lysosomal thiol reductase (GILT) Cid2 PF09774.9 KIY71467.1 - 1.2e-16 61.6 2.1 6.8e-16 59.1 2.1 1.9 1 1 0 1 1 1 1 Caffeine-induced death protein 2 zf-C2H2 PF00096.26 KIY71468.1 - 2.3e-06 27.7 11.9 0.00097 19.5 2.0 3.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIY71468.1 - 6.1e-05 23.5 9.6 0.05 14.5 0.2 4.1 3 1 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KIY71468.1 - 0.1 13.1 14.0 1.9 9.0 3.5 3.6 3 0 0 3 3 3 0 Zinc-finger double domain DUF3759 PF12585.8 KIY71469.1 - 9.1e-38 128.2 10.2 1.1e-37 127.9 10.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) DUF3336 PF11815.8 KIY71470.1 - 4.8e-52 175.3 1.6 7.8e-52 174.7 1.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 KIY71470.1 - 3.7e-17 63.2 0.1 4e-16 59.8 0.0 2.4 2 1 0 2 2 2 1 Patatin-like phospholipase TadE PF07811.12 KIY71470.1 - 0.11 12.8 3.4 0.21 11.9 3.4 1.4 1 0 0 1 1 1 0 TadE-like protein DUF4644 PF15486.6 KIY71470.1 - 0.61 9.8 3.3 0.22 11.3 0.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4644) PUB PF09409.10 KIY71471.1 - 4.3e-11 42.6 0.1 7.9e-11 41.7 0.0 1.5 1 1 0 1 1 1 1 PUB domain Membralin PF09746.9 KIY71471.1 - 0.57 9.2 0.0 0.57 9.2 0.0 1.9 2 0 0 2 2 2 0 Tumour-associated protein WD40 PF00400.32 KIY71472.1 - 4.6e-15 55.8 5.8 1.2e-06 29.1 0.2 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY71472.1 - 0.0046 17.2 0.0 0.018 15.3 0.0 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain PCI PF01399.27 KIY71473.1 - 2e-11 44.3 0.0 4.8e-11 43.1 0.0 1.7 1 0 0 1 1 1 1 PCI domain RPN7 PF10602.9 KIY71473.1 - 0.00067 19.4 0.5 0.0013 18.5 0.5 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 GCP_N_terminal PF17681.1 KIY71475.1 - 1.6e-98 330.1 0.0 3e-98 329.2 0.0 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 KIY71475.1 - 2.3e-92 309.8 0.3 4.9e-92 308.7 0.3 1.6 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal FA_desaturase PF00487.24 KIY71476.1 - 4.1e-16 59.6 31.2 6.7e-16 58.9 31.2 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 KIY71476.1 - 1.6e-13 50.6 0.0 4.4e-13 49.2 0.0 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FAT PF02259.23 KIY71478.1 - 2.2e-61 208.0 3.5 4.3e-61 207.1 3.5 1.5 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 KIY71478.1 - 1.4e-18 67.7 0.1 3.2e-18 66.5 0.1 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Bromodomain PF00439.25 KIY71479.1 - 5.2e-19 68.1 0.0 2.3e-18 66.1 0.0 2.0 2 0 0 2 2 2 1 Bromodomain CDC45 PF02724.14 KIY71479.1 - 0.27 9.5 6.6 0.33 9.2 6.6 1.2 1 0 0 1 1 1 0 CDC45-like protein CD99L2 PF12301.8 KIY71479.1 - 2.4 8.4 7.1 4.1 7.7 7.1 1.3 1 0 0 1 1 1 0 CD99 antigen like protein 2 Asp PF00026.23 KIY71480.1 - 1.4e-107 359.7 0.1 1.7e-107 359.5 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIY71480.1 - 5.1e-14 52.9 0.5 9.7e-12 45.5 0.5 2.5 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 KIY71480.1 - 1.3e-06 28.3 0.0 5e-05 23.1 0.0 2.6 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 KIY71480.1 - 5.4e-05 23.8 0.2 0.21 12.2 0.0 3.5 2 1 1 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.6 KIY71480.1 - 0.0025 18.4 0.0 1.5 9.4 0.0 2.8 2 1 0 2 2 2 2 gag-polyprotein putative aspartyl protease POT1 PF02765.17 KIY71481.1 - 7.6e-08 32.3 0.0 1.5e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 POT1PC PF16686.5 KIY71481.1 - 3.9e-07 30.1 0.1 0.45 10.4 0.0 4.3 4 0 0 4 4 4 3 ssDNA-binding domain of telomere protection protein Ribosomal_L5e PF17144.4 KIY71482.1 - 2.9e-82 274.5 0.1 5.8e-82 273.5 0.1 1.5 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 KIY71482.1 - 3.8e-35 120.7 3.0 3.8e-35 120.7 3.0 1.9 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Thr_synth_N PF14821.6 KIY71482.1 - 0.085 13.1 0.2 0.81 9.9 0.0 2.5 2 1 0 2 2 2 0 Threonine synthase N terminus RRM_1 PF00076.22 KIY71483.1 - 7.5e-14 51.3 0.1 1.2e-13 50.7 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Terminase_5 PF06056.12 KIY71484.1 - 0.001 18.9 0.1 0.0068 16.3 0.0 2.1 2 0 0 2 2 2 1 Putative ATPase subunit of terminase (gpP-like) HTH_23 PF13384.6 KIY71484.1 - 0.016 14.9 0.0 0.032 14.0 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain UPF0149 PF03695.13 KIY71485.1 - 0.065 13.5 0.0 0.09 13.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0149) Med13_C PF06333.12 KIY71486.1 - 0.15 11.3 2.5 0.24 10.6 2.5 1.3 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain TPR_19 PF14559.6 KIY71487.1 - 7.7e-15 55.2 4.2 1.7e-06 28.5 0.1 4.5 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KIY71487.1 - 3.2e-10 39.3 5.4 0.43 10.8 0.0 7.0 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 KIY71487.1 - 4.3e-10 39.6 7.1 0.67 10.9 0.0 7.0 4 2 3 7 7 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 KIY71487.1 - 1.4e-09 37.7 0.0 0.001 19.3 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KIY71487.1 - 4.5e-08 32.6 0.9 1.3 8.9 0.0 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 KIY71487.1 - 4e-06 27.4 4.7 2.2 9.0 0.0 5.1 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 KIY71487.1 - 0.0015 18.8 8.0 0.21 11.9 0.0 5.1 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 KIY71487.1 - 0.003 17.6 0.0 11 6.5 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_20 PF14561.6 KIY71487.1 - 0.0034 17.7 1.3 6.3 7.2 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 KIY71487.1 - 0.0073 16.1 2.5 0.47 10.4 0.0 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KIY71487.1 - 0.011 15.8 4.0 0.4 10.8 0.0 3.0 3 0 0 3 3 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.6 KIY71487.1 - 0.012 15.6 1.0 5.2 7.3 0.0 3.9 5 0 0 5 5 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 KIY71487.1 - 0.015 14.9 0.1 15 5.4 0.0 3.3 3 0 0 3 3 3 0 TPR repeat TPR_6 PF13174.6 KIY71487.1 - 0.025 15.2 0.8 1.3e+02 3.6 0.1 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.18 KIY71487.1 - 0.076 13.1 0.4 0.57 10.3 0.1 2.5 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain GBP PF02263.19 KIY71487.1 - 0.12 11.6 0.1 0.31 10.3 0.0 1.6 2 0 0 2 2 2 0 Guanylate-binding protein, N-terminal domain Alkyl_sulf_dimr PF14863.6 KIY71487.1 - 0.13 12.7 0.1 0.69 10.4 0.0 2.1 2 0 0 2 2 2 0 Alkyl sulfatase dimerisation DUF2529 PF10740.9 KIY71487.1 - 0.14 11.8 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2529) Svf1_C PF17187.4 KIY71489.1 - 6.4e-46 156.2 0.0 1.1e-45 155.4 0.0 1.4 1 0 0 1 1 1 1 Svf1-like C-terminal lipocalin-like domain Svf1 PF08622.10 KIY71489.1 - 2.2e-40 138.4 0.0 3.3e-40 137.8 0.0 1.3 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain Peptidase_M48 PF01435.18 KIY71490.1 - 4.4e-18 65.8 0.0 7.9e-18 64.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M48 DUF2428 PF10350.9 KIY71490.1 - 0.15 11.3 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Putative death-receptor fusion protein (DUF2428) DUF2268 PF10026.9 KIY71490.1 - 0.2 11.2 0.4 0.41 10.2 0.4 1.5 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) PRK PF00485.18 KIY71491.1 - 1.8e-49 168.2 0.0 2.8e-49 167.6 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.6 KIY71491.1 - 3.8e-46 157.1 0.0 3e-45 154.2 0.0 2.1 1 1 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_18 PF13238.6 KIY71491.1 - 9.2e-07 29.5 0.0 1.9e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KIY71491.1 - 3.1e-05 24.2 0.0 6.9e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KIY71491.1 - 0.0003 20.1 0.0 0.0006 19.2 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_17 PF13207.6 KIY71491.1 - 0.00063 20.2 0.2 1.5 9.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain KAP_NTPase PF07693.14 KIY71491.1 - 0.11 11.7 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 KAP family P-loop domain NB-ARC PF00931.22 KIY71491.1 - 0.12 11.5 0.2 0.22 10.7 0.2 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_19 PF13245.6 KIY71491.1 - 0.13 12.6 0.1 0.33 11.3 0.1 1.6 1 0 0 1 1 1 0 AAA domain CoaE PF01121.20 KIY71491.1 - 0.13 11.9 0.7 1.2 8.8 0.4 2.2 2 0 0 2 2 2 0 Dephospho-CoA kinase Lipase_GDSL_2 PF13472.6 KIY71492.1 - 1.4e-12 48.3 0.6 1.7e-12 48.1 0.6 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KIY71492.1 - 9.6e-05 22.4 0.1 0.00013 22.0 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Na_Ca_ex PF01699.24 KIY71493.1 - 2.8e-20 72.8 21.8 3.3e-10 40.1 2.7 2.4 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF872 PF05915.12 KIY71493.1 - 0.028 14.6 1.3 2.3 8.4 0.0 2.8 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) Plavaka PF18759.1 KIY71495.1 - 1.9e-118 395.4 0.0 2.9e-118 394.8 0.0 1.3 1 0 0 1 1 1 1 Plavaka transposase Peptidase_M20 PF01546.28 KIY71497.1 - 6.4e-26 91.3 0.0 1.1e-25 90.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.32 KIY71497.1 - 8.8e-12 45.4 13.0 3.3e-05 24.5 0.2 6.2 5 0 0 5 5 5 4 WD domain, G-beta repeat M20_dimer PF07687.14 KIY71497.1 - 2.9e-11 43.3 0.0 5.2e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Nup160 PF11715.8 KIY71497.1 - 6.8e-06 25.0 0.1 0.0073 15.0 0.0 2.3 2 0 0 2 2 2 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KIY71497.1 - 0.00015 22.0 0.5 0.31 11.4 0.1 3.5 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 KIY71497.1 - 0.014 13.9 0.0 2.6 6.5 0.0 2.1 2 0 0 2 2 2 0 Cytochrome D1 heme domain DUF3429 PF11911.8 KIY71498.1 - 4.7e-37 127.5 15.3 5.9e-37 127.2 15.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) COX5B PF01215.19 KIY71499.1 - 4.1e-47 159.1 0.0 4.9e-47 158.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-CHCC PF10276.9 KIY71499.1 - 0.0096 16.0 0.5 0.014 15.4 0.5 1.3 1 0 0 1 1 1 1 Zinc-finger domain Pyr_redox_2 PF07992.14 KIY71500.1 - 2.7e-19 69.5 0.0 3.6e-15 56.0 0.0 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIY71500.1 - 8.8e-09 35.8 0.0 1.7e-07 31.7 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KIY71500.1 - 0.084 12.0 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Abhydrolase_6 PF12697.7 KIY71501.1 - 1.9e-11 45.0 0.1 2.4e-11 44.6 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIY71501.1 - 0.025 13.9 0.0 0.04 13.2 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KIY71501.1 - 0.15 11.7 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold PfkB PF00294.24 KIY71502.1 - 4e-15 55.9 0.0 8.3e-07 28.6 0.0 3.1 3 0 0 3 3 3 3 pfkB family carbohydrate kinase SpoIIIAC PF06686.11 KIY71503.1 - 0.14 12.3 6.9 34 4.7 0.2 3.7 3 0 0 3 3 3 0 Stage III sporulation protein AC/AD protein family Hypoth_Ymh PF09509.10 KIY71503.1 - 5 7.0 7.6 40 4.1 0.1 3.7 4 0 0 4 4 4 0 Protein of unknown function (Hypoth_ymh) HSP20 PF00011.21 KIY71504.1 - 0.00011 22.2 0.2 0.0005 20.2 0.0 2.0 2 0 0 2 2 2 1 Hsp20/alpha crystallin family DUF3915 PF13054.6 KIY71504.1 - 0.0024 17.8 0.3 0.0039 17.2 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3915) Citrate_bind PF16114.5 KIY71504.1 - 0.2 11.1 0.0 0.33 10.4 0.0 1.2 1 0 0 1 1 1 0 ATP citrate lyase citrate-binding Peptidase_S49_N PF08496.10 KIY71504.1 - 1.7 8.7 4.8 53 3.8 5.0 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Presenilin PF01080.17 KIY71504.1 - 5.2 5.7 6.8 6.9 5.3 6.8 1.1 1 0 0 1 1 1 0 Presenilin SART-1 PF03343.13 KIY71505.1 - 4e-161 537.7 63.4 1.8e-160 535.6 61.6 1.9 2 0 0 2 2 2 2 SART-1 family GFO_IDH_MocA PF01408.22 KIY71507.1 - 2.6e-16 60.5 0.0 4.5e-16 59.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KIY71507.1 - 0.01 15.9 0.1 0.017 15.1 0.1 1.4 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain GGACT PF06094.12 KIY71508.1 - 5.3e-15 56.1 0.0 6.8e-15 55.7 0.0 1.1 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like Peptidase_C14 PF00656.22 KIY71509.1 - 3.9e-63 213.7 0.1 4.6e-63 213.5 0.1 1.0 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.6 KIY71509.1 - 0.036 14.0 2.1 0.044 13.7 0.1 2.2 3 0 0 3 3 3 0 Raptor N-terminal CASPase like domain Sugar_tr PF00083.24 KIY71511.1 - 4.6e-119 398.2 23.5 6.1e-119 397.8 23.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY71511.1 - 8.4e-29 100.6 43.7 6.7e-21 74.6 17.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3328 PF11807.8 KIY71512.1 - 0.031 14.0 0.0 0.034 13.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) DUF2207 PF09972.9 KIY71512.1 - 0.036 12.8 0.1 0.04 12.7 0.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF202 PF02656.15 KIY71512.1 - 0.096 13.1 0.5 0.15 12.5 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF202) HemY_N PF07219.13 KIY71512.1 - 1.4 9.1 3.4 2.3 8.5 3.4 1.2 1 0 0 1 1 1 0 HemY protein N-terminus Vps26 PF03643.15 KIY71513.1 - 7.1e-126 418.8 0.9 8.1e-126 418.6 0.9 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 KIY71513.1 - 0.0065 16.5 1.5 0.42 10.7 0.2 3.4 3 1 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain RNase_HII PF01351.18 KIY71514.1 - 7.5e-49 166.3 0.0 9.2e-49 166.0 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease HII Ribosomal_S11 PF00411.19 KIY71514.1 - 0.083 13.3 0.0 7.4 7.0 0.0 2.5 2 1 0 2 2 2 0 Ribosomal protein S11 RhoGEF PF00621.20 KIY71515.1 - 5.6e-28 98.4 0.2 8.3e-28 97.9 0.2 1.3 1 0 0 1 1 1 1 RhoGEF domain CNH PF00780.22 KIY71515.1 - 1.7e-22 80.3 0.0 2.8e-22 79.6 0.0 1.2 1 0 0 1 1 1 1 CNH domain PH_5 PF15405.6 KIY71515.1 - 5.3e-05 23.3 0.0 0.00024 21.2 0.0 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain Metallophos_2 PF12850.7 KIY71516.1 - 0.019 15.1 0.0 0.04 14.1 0.0 1.6 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain CTU2 PF10288.9 KIY71517.1 - 9.4e-16 58.0 3.5 1.8e-15 57.2 0.9 2.6 2 1 0 2 2 2 1 Cytoplasmic tRNA 2-thiolation protein 2 zf-C3HC4_3 PF13920.6 KIY71517.1 - 0.011 15.6 10.5 0.042 13.7 1.4 3.1 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) DZR PF12773.7 KIY71517.1 - 6.5 6.9 9.8 25 5.0 0.7 3.4 2 2 1 3 3 3 0 Double zinc ribbon CLZ PF16526.5 KIY71518.1 - 0.13 12.7 0.6 0.21 12.0 0.6 1.3 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels GAS PF13851.6 KIY71518.1 - 0.13 11.6 0.3 0.17 11.2 0.3 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding F_bP_aldolase PF01116.20 KIY71519.1 - 3.4e-87 292.5 0.0 3.8e-87 292.3 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Lipase_GDSL_2 PF13472.6 KIY71519.1 - 0.035 14.5 0.0 0.056 13.8 0.0 1.2 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family 3Beta_HSD PF01073.19 KIY71520.1 - 5.1e-65 219.3 0.0 3.2e-59 200.2 0.0 2.2 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KIY71520.1 - 6.1e-33 114.3 0.0 8.9e-33 113.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KIY71520.1 - 3.7e-17 62.7 0.3 5.6e-14 52.3 0.1 2.7 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KIY71520.1 - 6.1e-15 55.1 0.0 9.5e-15 54.4 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KIY71520.1 - 6.2e-14 51.8 0.0 8.3e-09 35.0 0.0 2.3 1 1 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 KIY71520.1 - 1.6e-11 44.4 0.0 2.9e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KIY71520.1 - 5.3e-07 29.1 0.0 1.7e-05 24.1 0.1 2.6 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.13 KIY71520.1 - 0.002 17.7 0.3 0.016 14.7 0.3 2.0 1 1 0 1 1 1 1 NmrA-like family KR PF08659.10 KIY71520.1 - 0.0066 16.4 0.4 0.041 13.8 0.4 2.3 1 1 0 1 1 1 1 KR domain Adeno_IVa2 PF02456.15 KIY71523.1 - 0.16 10.7 0.0 0.23 10.2 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein POP1 PF06978.11 KIY71524.1 - 9.9e-44 149.8 23.5 5.6e-23 82.0 8.3 2.7 2 1 1 3 3 3 2 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 KIY71524.1 - 1.5e-32 111.7 1.1 1.5e-32 111.7 1.1 2.1 2 0 0 2 2 2 1 POPLD (NUC188) domain GCV_T PF01571.21 KIY71524.1 - 2e-06 27.4 0.2 0.099 12.0 0.0 3.9 4 0 0 4 4 4 2 Aminomethyltransferase folate-binding domain THOC7 PF05615.13 KIY71525.1 - 4.1e-05 23.9 0.0 4.6e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Tho complex subunit 7 Spc7 PF08317.11 KIY71525.1 - 0.0029 16.5 0.9 0.0043 16.0 0.9 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein Seryl_tRNA_N PF02403.22 KIY71525.1 - 0.0096 16.1 0.4 0.015 15.5 0.4 1.3 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain SbcD_C PF12320.8 KIY71525.1 - 0.011 16.1 0.7 0.13 12.6 0.0 2.1 1 1 1 2 2 2 0 Type 5 capsule protein repressor C-terminal domain ACT_5 PF13710.6 KIY71525.1 - 0.021 14.6 0.2 20 5.1 0.0 3.1 3 0 0 3 3 3 0 ACT domain BLOC1_2 PF10046.9 KIY71525.1 - 0.025 14.9 1.5 0.047 14.0 1.0 1.7 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 MerR-DNA-bind PF09278.11 KIY71525.1 - 0.094 13.3 0.6 0.67 10.5 0.1 2.2 2 0 0 2 2 2 0 MerR, DNA binding NPV_P10 PF05531.12 KIY71525.1 - 0.099 13.1 0.7 0.24 11.9 0.2 1.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Syntaxin-6_N PF09177.11 KIY71525.1 - 0.11 13.1 1.2 0.35 11.4 1.3 1.8 1 1 1 2 2 2 0 Syntaxin 6, N-terminal SlyX PF04102.12 KIY71525.1 - 0.41 11.3 3.4 7.4 7.3 1.1 2.6 1 1 1 2 2 2 0 SlyX Exo_endo_phos PF03372.23 KIY71527.1 - 1.3e-05 24.8 0.3 3.3e-05 23.5 0.3 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF211 PF02680.14 KIY71527.1 - 0.13 12.4 0.1 0.39 10.9 0.1 1.8 1 0 0 1 1 1 0 Uncharacterized ArCR, COG1888 F-box-like PF12937.7 KIY71528.1 - 8.4e-06 25.6 0.1 2e-05 24.4 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY71528.1 - 0.00012 21.9 0.5 0.00084 19.2 0.1 2.3 2 0 0 2 2 2 1 F-box domain LRR_4 PF12799.7 KIY71528.1 - 0.058 13.8 0.0 65 4.2 0.0 3.9 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) adh_short PF00106.25 KIY71529.1 - 8.4e-45 152.6 0.2 1e-44 152.3 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIY71529.1 - 1e-32 113.6 0.1 1.3e-32 113.2 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIY71529.1 - 2.2e-05 24.4 0.1 3.9e-05 23.7 0.1 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KIY71529.1 - 0.045 13.1 0.1 0.12 11.8 0.0 1.6 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) Ldh_1_N PF00056.23 KIY71529.1 - 0.054 13.6 0.2 0.098 12.7 0.2 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 KIY71529.1 - 0.099 11.9 0.0 1.8 7.7 0.0 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Glyco_hydro_4 PF02056.16 KIY71529.1 - 0.099 12.2 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase Abhydrolase_6 PF12697.7 KIY71530.1 - 3.2e-10 41.0 0.1 4.3e-10 40.6 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KIY71530.1 - 2.3e-08 34.0 0.2 1.1e-07 31.7 0.2 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIY71530.1 - 1.7e-05 24.2 0.0 0.00018 20.9 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Zip PF02535.22 KIY71531.1 - 5.8e-25 88.2 19.2 1.6e-17 63.8 8.8 2.1 1 1 1 2 2 2 2 ZIP Zinc transporter DUF1689 PF07954.11 KIY71531.1 - 0.028 14.8 0.0 0.053 13.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1689) YrhC PF14143.6 KIY71531.1 - 2.7 8.1 5.0 2.4 8.3 0.3 3.0 2 1 1 3 3 3 0 YrhC-like protein WD40 PF00400.32 KIY71532.1 - 3.4e-10 40.3 8.4 0.025 15.4 0.0 5.9 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY71532.1 - 5.1e-10 39.5 0.1 0.0027 18.0 0.0 4.8 1 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIY71532.1 - 1.4e-07 31.6 0.0 0.0088 15.9 0.0 3.5 1 1 3 4 4 4 3 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 KIY71532.1 - 0.00096 17.8 0.0 0.0067 15.0 0.0 1.9 2 0 0 2 2 2 1 Cytochrome D1 heme domain PD40 PF07676.12 KIY71532.1 - 0.011 15.7 0.7 0.46 10.5 0.0 3.1 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat F-box PF00646.33 KIY71533.1 - 1.2e-05 25.1 1.1 3.9e-05 23.4 1.1 1.9 1 1 0 1 1 1 1 F-box domain F-box-like PF12937.7 KIY71533.1 - 1.2e-05 25.1 0.9 2.1e-05 24.3 0.9 1.5 1 0 0 1 1 1 1 F-box-like Pkinase PF00069.25 KIY71535.1 - 1.2e-52 178.9 0.0 1.5e-52 178.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY71535.1 - 1.1e-28 100.2 0.0 3.2e-26 92.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KIY71535.1 - 0.00014 21.3 0.0 0.00021 20.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KIY71535.1 - 0.0013 18.1 0.7 0.002 17.5 0.1 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KIY71535.1 - 0.0019 17.8 0.2 0.0084 15.7 0.1 2.0 2 0 0 2 2 2 1 RIO1 family Pkinase_fungal PF17667.1 KIY71535.1 - 0.0024 16.7 0.1 0.0037 16.1 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KIY71535.1 - 0.048 13.6 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 KIY71535.1 - 0.055 13.1 0.0 0.084 12.5 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Ribosomal_S19e PF01090.19 KIY71536.1 - 3.1e-56 188.9 0.1 3.7e-56 188.6 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e NMO PF03060.15 KIY71537.1 - 7.7e-56 189.9 0.9 3.5e-55 187.7 0.9 1.8 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KIY71537.1 - 3.3e-08 32.9 0.2 1.1e-05 24.7 0.2 2.2 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KIY71537.1 - 0.0069 15.5 0.4 0.011 14.8 0.4 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase TMP-TENI PF02581.17 KIY71537.1 - 0.0088 15.4 0.1 0.017 14.5 0.1 1.4 1 0 0 1 1 1 1 Thiamine monophosphate synthase His_biosynth PF00977.21 KIY71537.1 - 0.045 13.2 0.1 0.089 12.2 0.1 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein AhpC-TSA PF00578.21 KIY71538.1 - 4e-15 55.8 0.0 1.2e-14 54.3 0.0 1.6 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KIY71538.1 - 9.1e-08 31.9 0.0 1.2e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Redoxin Pribosyltran_N PF13793.6 KIY71540.1 - 6.4e-45 151.8 0.6 1.7e-43 147.2 0.3 2.2 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 KIY71540.1 - 7.4e-40 136.9 2.6 2.1e-34 119.1 0.3 2.6 2 1 1 3 3 3 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 KIY71540.1 - 2.3e-15 56.4 1.6 2.8e-15 56.2 0.5 1.7 2 0 0 2 2 2 1 Phosphoribosyl transferase domain zf-Tim10_DDP PF02953.15 KIY71541.1 - 3.5e-18 65.0 6.5 3.5e-18 65.0 6.5 1.5 1 1 0 1 1 1 1 Tim10/DDP family zinc finger Tam41_Mmp37 PF09139.11 KIY71541.1 - 0.043 13.3 0.2 0.045 13.2 0.2 1.0 1 0 0 1 1 1 0 Phosphatidate cytidylyltransferase, mitochondrial DAHP_synth_1 PF00793.20 KIY71542.1 - 4.9e-97 324.1 0.0 6.2e-97 323.7 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Glyco_transf_28 PF03033.20 KIY71543.1 - 6.3e-28 97.5 0.0 1.5e-27 96.4 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 KIY71543.1 - 5e-07 28.9 0.0 1.2e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Nup96 PF12110.8 KIY71544.1 - 1.8e-62 211.1 0.0 4.1e-60 203.4 0.0 2.3 1 1 0 1 1 1 1 Nuclear protein 96 COE1_HLH PF16423.5 KIY71544.1 - 0.05 13.3 0.0 0.56 10.0 0.0 2.3 2 0 0 2 2 2 0 Transcription factor COE1 helix-loop-helix domain SDA1 PF05285.12 KIY71544.1 - 0.12 11.8 8.2 0.18 11.2 8.2 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 KIY71544.1 - 0.26 9.4 11.2 0.47 8.6 11.2 1.3 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 KIY71544.1 - 0.31 9.3 6.5 0.43 8.8 6.5 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF2457 PF10446.9 KIY71544.1 - 0.39 9.8 11.3 0.63 9.1 11.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PTPRCAP PF15713.5 KIY71544.1 - 1.1 9.5 9.5 2.2 8.6 9.5 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated TRAP_alpha PF03896.16 KIY71544.1 - 4.5 6.4 6.8 7.5 5.7 6.8 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit TAF1D PF15333.6 KIY71545.1 - 0.13 12.0 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 TATA box-binding protein-associated factor 1D RGS PF00615.19 KIY71547.1 - 0.00094 19.4 0.0 0.0016 18.7 0.0 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain DUF1856 PF08983.10 KIY71547.1 - 0.0028 17.8 0.3 0.0069 16.6 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1856) DUF3188 PF11384.8 KIY71547.1 - 0.25 11.1 1.0 0.49 10.1 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3188) VHS PF00790.19 KIY71548.1 - 4.8e-37 126.9 0.0 1.4e-36 125.4 0.0 1.8 2 0 0 2 2 2 1 VHS domain GAT PF03127.14 KIY71548.1 - 2.2e-18 66.3 1.5 4.8e-18 65.2 0.2 2.3 3 0 0 3 3 3 1 GAT domain GGA_N-GAT PF18308.1 KIY71548.1 - 0.029 14.0 0.4 0.067 12.8 0.4 1.6 1 0 0 1 1 1 0 GGA N-GAT domain HR1 PF02185.16 KIY71548.1 - 0.35 11.0 0.1 0.35 11.0 0.1 2.3 3 0 0 3 3 3 0 Hr1 repeat F-box-like PF12937.7 KIY71549.1 - 7.6e-09 35.3 2.2 2.2e-08 33.9 2.2 1.9 1 0 0 1 1 1 1 F-box-like GRAM PF02893.20 KIY71549.1 - 0.071 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 GRAM domain DHHC PF01529.20 KIY71550.1 - 1.7e-30 105.9 7.3 1.7e-30 105.9 7.3 2.6 2 1 1 3 3 3 1 DHHC palmitoyltransferase Ank_2 PF12796.7 KIY71550.1 - 6.7e-28 97.1 0.1 1.6e-13 51.0 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KIY71550.1 - 4.7e-25 87.3 2.1 3.6e-09 36.7 0.0 4.5 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 KIY71550.1 - 5.5e-23 80.4 0.6 0.00051 20.4 0.1 5.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 KIY71550.1 - 5.3e-22 77.9 1.1 2.2e-06 28.1 0.1 5.3 1 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIY71550.1 - 4.3e-21 72.7 0.5 8.7e-05 22.6 0.0 6.3 6 0 0 6 6 6 4 Ankyrin repeat DUF3270 PF11674.8 KIY71550.1 - 0.48 10.6 10.1 0.33 11.2 1.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3270) PocR PF10114.9 KIY71550.1 - 0.49 10.2 1.8 0.88 9.3 1.8 1.3 1 0 0 1 1 1 0 Sensory domain found in PocR TniQ PF06527.11 KIY71550.1 - 1.2 9.8 7.0 2.4 8.9 5.7 2.2 2 1 0 2 2 2 0 TniQ Telomere_reg-2 PF10193.9 KIY71551.1 - 2e-28 99.0 0.0 3.9e-28 98.1 0.0 1.5 1 0 0 1 1 1 1 Telomere length regulation protein zf-C2H2_jaz PF12171.8 KIY71552.1 - 6.9e-07 29.4 7.7 0.22 11.9 0.0 4.8 4 1 1 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KIY71552.1 - 2.3e-06 28.0 24.4 0.064 14.1 3.1 5.4 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2 PF00096.26 KIY71552.1 - 2.5e-05 24.5 17.8 0.12 12.9 2.0 4.7 4 0 0 4 4 4 3 Zinc finger, C2H2 type Actin_micro PF17003.5 KIY71552.1 - 0.0021 17.3 0.1 2.5 7.2 0.0 3.0 1 1 1 2 2 2 1 Putative actin-like family zf-met PF12874.7 KIY71552.1 - 0.025 15.0 9.5 2.5 8.6 0.0 4.0 4 0 0 4 4 4 0 Zinc-finger of C2H2 type Vps36-NZF-N PF16988.5 KIY71552.1 - 1.4 8.4 5.6 8.3 5.9 0.4 2.7 2 1 1 3 3 3 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-C2H2_6 PF13912.6 KIY71552.1 - 2.7 8.1 10.5 6.7 6.8 0.3 4.3 4 0 0 4 4 4 0 C2H2-type zinc finger DUF629 PF04780.12 KIY71552.1 - 4.7 5.6 9.2 6.7 5.1 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF629) Rhodanese PF00581.20 KIY71553.1 - 2.1e-14 53.9 0.0 4.1e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain DUF1772 PF08592.11 KIY71555.1 - 5.1 7.4 10.6 3 8.2 1.3 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF1772) BTB PF00651.31 KIY71556.1 - 0.0028 17.9 0.0 0.0057 16.9 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain F-box-like PF12937.7 KIY71557.1 - 5.2e-10 39.1 0.0 3.4e-09 36.4 0.0 2.2 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KIY71557.1 - 0.13 12.1 0.5 25 4.9 0.1 2.7 2 0 0 2 2 2 0 F-box domain AGH PF17558.2 KIY71557.1 - 1.1 9.5 6.3 1.9 8.7 3.8 2.3 2 0 0 2 2 2 0 Androgenic gland hormone ER_lumen_recept PF00810.18 KIY71558.1 - 3.7e-41 141.4 13.8 5.7e-41 140.8 13.8 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor DUF3561 PF12084.8 KIY71558.1 - 0.0059 16.6 2.7 0.0059 16.6 2.7 2.7 1 1 2 3 3 3 1 Protein of unknown function (DUF3561) PQ-loop PF04193.14 KIY71558.1 - 0.046 13.5 0.2 0.046 13.5 0.2 4.4 5 0 0 5 5 5 0 PQ loop repeat zf-C2H2 PF00096.26 KIY71559.1 - 7.3e-12 45.1 12.3 5.3e-06 26.6 2.3 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KIY71559.1 - 9e-07 29.1 4.9 9e-07 29.1 4.9 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KIY71559.1 - 7.2e-06 26.4 11.4 0.0019 18.8 1.8 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger FOXP-CC PF16159.5 KIY71559.1 - 5.6e-05 23.7 4.6 0.085 13.5 0.8 2.2 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 KIY71559.1 - 0.0013 18.7 0.2 0.0013 18.7 0.2 2.7 2 1 0 2 2 2 1 C2H2-type zinc finger IBR PF01485.21 KIY71559.1 - 0.021 15.0 1.6 0.67 10.2 0.1 2.1 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain zf-C2H2_aberr PF17017.5 KIY71559.1 - 0.18 11.9 4.0 4.1 7.5 0.7 2.1 1 1 1 2 2 2 0 Aberrant zinc-finger zf-met PF12874.7 KIY71559.1 - 0.18 12.2 2.1 1.8 9.1 0.3 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KIY71559.1 - 0.6 9.9 15.6 1.3 8.9 3.7 3.0 2 1 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 KIY71559.1 - 0.72 10.2 6.7 1 9.8 0.2 2.5 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 KIY71559.1 - 1.3 8.8 8.4 0.19 11.5 2.4 2.4 2 0 0 2 2 2 0 zinc-finger C2H2-type Plk4_PB2 PF18409.1 KIY71560.1 - 7.3e-08 33.1 0.0 1e-06 29.4 0.0 2.4 2 0 0 2 2 2 1 Polo-like Kinase 4 Polo Box 2 Tudor_3 PF18115.1 KIY71560.1 - 0.14 12.0 0.0 0.35 10.7 0.0 1.6 1 0 0 1 1 1 0 DNA repair protein Crb2 Tudor domain COX5A PF02284.16 KIY71561.1 - 3.6e-42 142.5 0.3 4.7e-42 142.2 0.3 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va Glyco_hydro_17 PF00332.18 KIY71561.1 - 0.037 13.6 0.0 0.062 12.9 0.0 1.3 1 1 0 1 1 1 0 Glycosyl hydrolases family 17 HHH_8 PF14716.6 KIY71561.1 - 0.068 13.6 0.2 0.14 12.5 0.2 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix domain Mit_KHE1 PF10173.9 KIY71562.1 - 3.6e-55 187.0 0.1 4.5e-55 186.7 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related Rax2 PF12768.7 KIY71563.1 - 0.024 14.1 0.0 0.039 13.4 0.0 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Amnionless PF14828.6 KIY71563.1 - 0.26 10.1 0.0 0.4 9.5 0.0 1.1 1 0 0 1 1 1 0 Amnionless MFS_1 PF07690.16 KIY71564.1 - 4.4e-39 134.4 48.5 1.6e-37 129.2 47.0 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIY71564.1 - 2.5e-08 33.3 23.8 5.1e-08 32.2 14.6 2.8 2 1 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 KIY71564.1 - 5.3e-06 25.1 14.0 1.2e-05 24.0 13.4 1.8 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 KIY71564.1 - 8.4e-06 24.6 31.0 8.1e-05 21.4 5.2 3.9 2 2 2 4 4 4 3 MFS/sugar transport protein BTB PF00651.31 KIY71565.1 - 9.4e-07 29.1 0.0 1.5e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain MFS_1 PF07690.16 KIY71566.1 - 3.7e-32 111.6 53.3 3.7e-32 111.6 53.3 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KIY71566.1 - 4.7e-15 55.0 19.4 6.4e-15 54.6 19.4 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KIY71566.1 - 6.2e-15 55.0 34.6 4.2e-13 49.0 12.9 2.9 2 1 1 3 3 3 2 Sugar (and other) transporter Na_Ca_ex PF01699.24 KIY71568.1 - 5.1e-17 62.2 24.9 1.9e-09 37.7 9.4 2.6 3 0 0 3 3 3 2 Sodium/calcium exchanger protein Ubie_methyltran PF01209.18 KIY71569.1 - 1.3e-80 270.1 0.0 2.2e-80 269.3 0.0 1.3 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 KIY71569.1 - 1.9e-14 54.1 0.0 3.9e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIY71569.1 - 2.9e-12 47.1 0.0 4.6e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIY71569.1 - 7.2e-10 38.9 0.0 1.4e-09 37.9 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIY71569.1 - 2.4e-09 37.8 0.0 3.8e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIY71569.1 - 3.8e-08 33.3 0.0 5.7e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.26 KIY71569.1 - 0.023 14.7 0.0 0.039 13.9 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase AKAP7_NLS PF10469.9 KIY71570.1 - 3.3e-20 72.9 0.0 5.5e-20 72.1 0.0 1.3 1 1 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.6 KIY71570.1 - 0.00035 20.5 0.1 0.0014 18.5 0.1 1.8 1 1 1 2 2 2 1 2'-5' RNA ligase superfamily ATP_transf PF09830.9 KIY71571.1 - 0.13 12.5 0.0 0.26 11.5 0.0 1.6 1 0 0 1 1 1 0 ATP adenylyltransferase RMI2 PF16100.5 KIY71572.1 - 0.11 12.3 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 RecQ-mediated genome instability protein 2 EAF PF09816.9 KIY71573.1 - 2.8e-09 37.3 0.0 4.7e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor R3H PF01424.22 KIY71574.1 - 2.2e-14 53.2 0.0 3e-12 46.3 0.0 2.5 2 0 0 2 2 2 1 R3H domain G-patch PF01585.23 KIY71574.1 - 4.9e-10 39.1 1.1 4.9e-10 39.1 1.1 3.1 3 0 0 3 3 3 1 G-patch domain G-patch_2 PF12656.7 KIY71574.1 - 0.00049 20.1 1.1 0.0019 18.3 1.1 2.1 1 0 0 1 1 1 1 G-patch domain HTH_21 PF13276.6 KIY71574.1 - 0.044 13.9 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 HTH-like domain FTA4 PF13093.6 KIY71574.1 - 0.078 12.9 0.6 0.15 11.9 0.6 1.4 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Hum_adeno_E3A PF05393.11 KIY71575.1 - 0.062 13.3 0.8 0.13 12.3 0.1 1.9 2 0 0 2 2 2 0 Human adenovirus early E3A glycoprotein Glyco_hydro_85 PF03644.13 KIY71576.1 - 3.1e-85 286.2 0.0 4.5e-85 285.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 ETX_MTX2 PF03318.13 KIY71576.1 - 0.034 13.9 0.1 0.064 13.0 0.1 1.4 1 0 0 1 1 1 0 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 MRP-S33 PF08293.11 KIY71578.1 - 1.2e-26 92.7 0.8 1.2e-26 92.7 0.8 1.5 2 0 0 2 2 2 1 Mitochondrial ribosomal subunit S27 CRISPR_Cas2 PF09827.9 KIY71578.1 - 0.067 13.4 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 CRISPR associated protein Cas2 AOX PF01786.17 KIY71579.1 - 1.1e-94 316.0 0.0 1.4e-94 315.7 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase Peptidase_S66C PF17676.1 KIY71579.1 - 0.03 14.9 0.0 0.073 13.6 0.0 1.6 1 1 0 1 1 1 0 LD-carboxypeptidase C-terminal domain CDO_I PF05995.12 KIY71581.1 - 2.9e-06 26.7 0.0 4.9e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 KIY71581.1 - 0.037 13.5 0.0 0.074 12.5 0.0 1.4 1 0 0 1 1 1 0 PCO_ADO DUF2235 PF09994.9 KIY71582.1 - 1.3e-39 136.3 0.0 1.9e-39 135.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) ADH_zinc_N PF00107.26 KIY71583.1 - 3.3e-12 46.5 1.1 3.3e-12 46.5 1.1 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIY71583.1 - 1.1e-08 34.9 0.1 2.6e-08 33.7 0.1 1.6 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KIY71583.1 - 0.0004 21.4 0.0 0.00084 20.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KIY71585.1 - 7.8e-14 51.8 2.0 7.8e-14 51.8 2.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIY71585.1 - 2.4e-08 33.8 0.1 8.5e-08 32.1 0.1 1.9 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KIY71585.1 - 2.3e-05 25.4 0.1 4.6e-05 24.5 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DNA_ligase_A_M PF01068.21 KIY71586.1 - 2.8e-66 223.0 0.1 4.4e-66 222.4 0.1 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KIY71586.1 - 2.6e-45 154.8 0.7 5.1e-45 153.9 0.7 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 KIY71586.1 - 2.6e-25 88.9 0.0 8.3e-25 87.3 0.0 1.9 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 KIY71586.1 - 2.5e-05 24.6 0.0 5.5e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 RNA ligase DNA_ligase_OB_2 PF14743.6 KIY71586.1 - 0.036 14.1 0.1 6.6 6.8 0.0 2.7 2 0 0 2 2 2 0 DNA ligase OB-like domain RhoGEF PF00621.20 KIY71586.1 - 0.1 12.9 0.0 0.53 10.5 0.0 2.2 3 0 0 3 3 3 0 RhoGEF domain ETC_C1_NDUFA5 PF04716.14 KIY71587.1 - 3.1e-26 91.0 0.3 4.2e-26 90.5 0.3 1.2 1 0 0 1 1 1 1 ETC complex I subunit conserved region DSX_dimer PF08828.10 KIY71587.1 - 0.024 14.3 0.1 0.041 13.5 0.1 1.3 1 0 0 1 1 1 0 Doublesex dimerisation domain Ribosomal_L32p PF01783.23 KIY71588.1 - 1.7e-15 57.0 5.3 2.1e-15 56.7 5.3 1.2 1 0 0 1 1 1 1 Ribosomal L32p protein family zinc-ribbons_6 PF07191.12 KIY71588.1 - 0.0031 17.5 0.4 0.0043 17.0 0.4 1.2 1 0 0 1 1 1 1 zinc-ribbons Prok-RING_1 PF14446.6 KIY71588.1 - 0.019 14.9 3.0 0.043 13.7 0.7 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 DZR PF12773.7 KIY71588.1 - 0.02 14.9 0.6 0.029 14.4 0.6 1.3 1 0 0 1 1 1 0 Double zinc ribbon Zn-ribbon_8 PF09723.10 KIY71588.1 - 0.095 12.8 1.4 2.9 8.1 1.8 2.1 1 1 1 2 2 2 0 Zinc ribbon domain RecR PF02132.15 KIY71588.1 - 0.21 11.2 1.8 0.34 10.5 1.8 1.3 1 0 0 1 1 1 0 RecR protein zinc_ribbon_4 PF13717.6 KIY71588.1 - 1 9.3 4.5 1.7 8.6 0.2 2.6 3 0 0 3 3 3 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 KIY71588.1 - 1.1 8.7 6.9 4.2 6.9 6.9 1.8 1 1 0 1 1 1 0 zinc-ribbon domain DUF35_N PF12172.8 KIY71588.1 - 4.7 7.2 5.9 14 5.7 5.9 1.8 1 1 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Gly_transf_sug PF04488.15 KIY71590.1 - 2.8e-05 24.6 0.0 6.1e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 KIY71590.1 - 0.045 13.1 0.4 0.066 12.6 0.4 1.2 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein Pkinase PF00069.25 KIY71591.1 - 2e-68 230.6 0.0 1.2e-65 221.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIY71591.1 - 6.7e-35 120.6 0.0 2.9e-31 108.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIY71591.1 - 1.1e-05 24.4 0.0 1.6e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KIY71591.1 - 0.0015 17.9 0.0 0.0033 16.8 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 KIY71591.1 - 0.02 14.2 0.3 0.081 12.3 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 KIY71591.1 - 0.077 12.5 0.2 0.19 11.2 0.0 1.6 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL MAGI_u1 PF16663.5 KIY71591.1 - 0.15 12.2 3.7 2.1 8.5 0.2 2.7 2 0 0 2 2 2 0 Unstructured region on MAGI Helicase_C_2 PF13307.6 KIY71593.1 - 0.019 15.1 0.0 0.045 13.9 0.0 1.6 1 0 0 1 1 1 0 Helicase C-terminal domain Hydrolase_4 PF12146.8 KIY71593.1 - 0.057 12.7 0.0 0.16 11.2 0.0 1.7 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Lyase_8 PF02278.18 KIY71594.1 - 3e-67 226.8 2.8 6.4e-67 225.7 2.8 1.6 1 0 0 1 1 1 1 Polysaccharide lyase family 8, super-sandwich domain Lyase_8_N PF08124.11 KIY71594.1 - 9.7e-20 70.7 0.0 1.7e-19 69.9 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide lyase family 8, N terminal alpha-helical domain Lyase_8_C PF02884.17 KIY71594.1 - 2.8e-10 40.5 0.6 7.5e-10 39.2 0.6 1.8 1 0 0 1 1 1 1 Polysaccharide lyase family 8, C-terminal beta-sandwich domain Invasin_D3 PF09134.10 KIY71594.1 - 0.07 13.4 2.4 0.15 12.4 0.0 2.6 3 0 0 3 3 3 0 Invasin, domain 3 MutS_V PF00488.21 KIY71595.1 - 3e-68 229.6 0.6 1.1e-67 227.8 0.1 2.2 3 0 0 3 3 3 1 MutS domain V MutS_III PF05192.18 KIY71595.1 - 7.5e-35 120.9 1.2 7.5e-35 120.9 1.2 2.3 3 1 0 3 3 3 1 MutS domain III MutS_I PF01624.20 KIY71595.1 - 3.5e-28 98.1 0.1 8.7e-28 96.8 0.1 1.7 1 0 0 1 1 1 1 MutS domain I MutS_IV PF05190.18 KIY71595.1 - 3.2e-08 33.8 0.1 1e-07 32.2 0.1 1.9 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 KIY71595.1 - 8e-07 29.4 0.0 2e-06 28.1 0.0 1.8 1 0 0 1 1 1 1 MutS domain II DUF4911 PF16256.5 KIY71595.1 - 0.041 13.8 0.0 0.14 12.1 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4911) DUF4754 PF15946.5 KIY71595.1 - 0.1 12.9 0.0 0.27 11.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4754) Sec2p PF06428.11 KIY71595.1 - 0.1 12.6 0.2 0.32 11.0 0.2 1.8 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p DUF4006 PF13179.6 KIY71597.1 - 7 6.6 0.0 7 6.6 0.0 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF4006) Mpp10 PF04006.12 KIY71598.1 - 4.1e-124 415.3 54.5 5.4e-124 414.9 54.5 1.0 1 0 0 1 1 1 1 Mpp10 protein UL20 PF17582.2 KIY71598.1 - 0.27 10.5 0.0 0.42 9.9 0.0 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL20 NUDE_C PF04880.13 KIY71601.1 - 6.4 7.2 5.7 4.7 7.6 3.4 1.9 2 0 0 2 2 2 0 NUDE protein, C-terminal conserved region BNIP2 PF12496.8 KIY71602.1 - 0.36 11.3 6.5 0.25 11.8 5.1 1.5 1 1 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Mucin PF01456.17 KIY71604.1 - 0.0044 17.0 5.8 0.0054 16.7 5.8 1.1 1 0 0 1 1 1 1 Mucin-like glycoprotein DUF1180 PF06679.12 KIY71604.1 - 0.22 11.9 11.7 0.37 11.2 11.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) SOG2 PF10428.9 KIY71604.1 - 1.5 8.0 8.8 1.5 7.9 8.8 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein BPS1 PF05633.11 KIY71604.1 - 1.9 7.4 4.0 2.5 7.0 4.0 1.2 1 0 0 1 1 1 0 Protein BYPASS1-related Apt1 PF10351.9 KIY71604.1 - 2.8 6.7 7.6 3.1 6.6 7.6 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Menin PF05053.13 KIY71604.1 - 5.2 5.3 9.5 6.3 5.0 9.5 1.1 1 0 0 1 1 1 0 Menin UPF0160 PF03690.13 KIY71606.1 - 2e-133 445.0 0.0 2.3e-133 444.8 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) SAD_SRA PF02182.17 KIY71607.1 - 5.3e-53 178.9 0.0 1.3e-52 177.7 0.0 1.7 1 0 0 1 1 1 1 SAD/SRA domain zf_CCCH_4 PF18345.1 KIY71607.1 - 6.8e-05 22.8 21.9 0.0013 18.7 3.9 3.7 3 0 0 3 3 3 3 Zinc finger domain zf-CCCH PF00642.24 KIY71607.1 - 0.00088 19.1 21.0 0.002 18.0 3.6 3.7 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KIY71607.1 - 0.075 13.7 13.5 0.037 14.7 1.5 3.5 2 1 1 3 3 3 0 Torus domain zf-CCCH_3 PF15663.5 KIY71607.1 - 0.49 10.6 9.0 0.1 12.8 1.3 2.7 2 0 0 2 2 2 0 Zinc-finger containing family CheZ PF04344.13 KIY71607.1 - 0.74 9.7 5.9 0.39 10.6 1.2 2.2 2 0 0 2 2 2 0 Chemotaxis phosphatase, CheZ TACC_C PF05010.14 KIY71607.1 - 3 7.6 10.1 1 9.1 3.5 2.2 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal BRE1 PF08647.11 KIY71607.1 - 5.3 7.2 9.3 10 6.2 0.8 2.7 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase XhlA PF10779.9 KIY71608.1 - 0.0098 16.1 1.0 0.0098 16.1 1.0 3.2 2 2 1 3 3 3 2 Haemolysin XhlA V-SNARE_C PF12352.8 KIY71608.1 - 0.1 12.9 5.8 0.32 11.3 0.8 2.6 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus DUF1490 PF07371.12 KIY71608.1 - 1.5 8.9 4.8 0.34 11.0 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1490) Ribosomal_S3_C PF00189.20 KIY71609.1 - 9.8e-25 86.9 0.1 3.4e-24 85.2 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 KIY71609.1 - 6.5e-11 41.9 0.0 1.1e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.8 KIY71609.1 - 0.066 13.7 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 RasGEF PF00617.19 KIY71610.1 - 8.4e-34 117.3 0.1 1.5e-33 116.5 0.1 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KIY71610.1 - 5.3e-10 39.5 0.0 1.6e-09 37.9 0.0 1.9 1 0 0 1 1 1 1 RasGEF N-terminal motif Viral_helicase1 PF01443.18 KIY71610.1 - 0.0055 16.5 0.1 0.011 15.5 0.1 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Ras PF00071.22 KIY71610.1 - 0.0093 15.6 0.1 0.41 10.2 0.0 2.3 2 0 0 2 2 2 1 Ras family RsgA_GTPase PF03193.16 KIY71610.1 - 0.0094 15.9 0.0 5.9 6.8 0.1 2.6 3 0 0 3 3 3 2 RsgA GTPase AAA_16 PF13191.6 KIY71610.1 - 0.061 13.7 0.1 0.38 11.1 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 KIY71610.1 - 0.071 13.4 0.0 0.21 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain SPX PF03105.19 KIY71610.1 - 0.11 12.3 3.8 0.2 11.5 2.9 1.9 2 0 0 2 2 2 0 SPX domain Rad17 PF03215.15 KIY71610.1 - 0.12 12.3 0.1 0.24 11.3 0.1 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain Sec7 PF01369.20 KIY71610.1 - 0.13 11.9 0.0 0.35 10.5 0.0 1.7 2 0 0 2 2 2 0 Sec7 domain Lebercilin PF15619.6 KIY71610.1 - 0.22 11.2 1.2 0.45 10.1 1.2 1.4 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease SurE PF01975.17 KIY71611.1 - 5.8e-47 160.0 0.0 7.1e-47 159.7 0.0 1.1 1 0 0 1 1 1 1 Survival protein SurE DUF4562 PF15123.6 KIY71611.1 - 0.14 12.1 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4562) DEAD PF00270.29 KIY71612.1 - 1e-48 165.4 0.1 6.6e-48 162.8 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIY71612.1 - 4.7e-31 107.4 0.2 1.7e-29 102.4 0.1 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIY71612.1 - 2.7e-06 27.5 0.0 2.8e-05 24.2 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 KIY71612.1 - 0.048 12.4 0.2 0.4 9.4 0.0 2.4 2 1 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 ANAPC4 PF12896.7 KIY71613.1 - 3.7e-40 137.6 3.2 8e-40 136.5 3.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 ANAPC4_WD40 PF12894.7 KIY71613.1 - 1.2e-07 31.9 0.1 2.5e-07 30.9 0.1 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain bZIP_1 PF00170.21 KIY71614.1 - 0.00024 21.1 5.2 0.00042 20.4 5.2 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KIY71614.1 - 0.029 14.4 4.9 0.029 14.4 4.9 2.7 2 1 1 3 3 3 0 Basic region leucine zipper Trimer_CC PF08954.11 KIY71614.1 - 0.067 12.8 1.4 0.18 11.4 1.4 1.7 1 0 0 1 1 1 0 Trimerisation motif ZapB PF06005.12 KIY71614.1 - 0.18 12.3 2.6 0.32 11.5 2.6 1.3 1 0 0 1 1 1 0 Cell division protein ZapB Prominin PF05478.11 KIY71614.1 - 0.64 7.9 1.5 0.86 7.5 1.5 1.0 1 0 0 1 1 1 0 Prominin DUF3523 PF12037.8 KIY71614.1 - 2.2 7.6 8.8 3.6 6.9 8.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) DPBB_1 PF03330.18 KIY71615.1 - 0.0044 17.3 0.0 0.0091 16.3 0.0 1.6 1 1 0 1 1 1 1 Lytic transglycolase Mucin-like PF16058.5 KIY71615.1 - 0.13 12.4 13.6 0.21 11.7 13.6 1.3 1 0 0 1 1 1 0 Mucin-like XPG_N PF00752.17 KIY71616.1 - 8.4e-34 116.1 0.0 1.9e-33 114.9 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 KIY71616.1 - 4.1e-29 100.8 0.1 1.6e-28 98.9 0.0 2.0 2 0 0 2 2 2 1 XPG I-region 5_3_exonuc PF01367.20 KIY71616.1 - 1.3e-06 29.0 0.0 3e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold Methyltransf_23 PF13489.6 KIY71617.1 - 9.6e-11 41.8 0.0 1.3e-10 41.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIY71617.1 - 1.7e-09 38.2 0.0 2.8e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIY71617.1 - 1e-07 32.6 0.0 1.9e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIY71617.1 - 4.9e-07 30.4 0.0 8.3e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIY71617.1 - 0.0011 18.8 0.1 0.0053 16.6 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain RasGAP PF00616.19 KIY71620.1 - 2.2e-29 102.7 0.0 9.5e-27 94.1 0.0 2.2 1 1 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 KIY71620.1 - 6.3e-12 45.7 0.0 1.1e-11 44.9 0.0 1.4 1 0 0 1 1 1 1 C2 domain ELO PF01151.18 KIY71621.1 - 1.8e-57 194.8 18.5 2.1e-57 194.5 18.5 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family SNARE_assoc PF09335.11 KIY71621.1 - 2.6 8.5 7.5 0.42 11.1 0.5 2.7 2 1 1 3 3 3 0 SNARE associated Golgi protein VPS13_mid_rpt PF16910.5 KIY71623.1 - 3.1e-97 324.6 13.1 5.8e-93 310.7 1.1 5.0 4 1 1 5 5 5 3 Repeating coiled region of VPS13 VPS13 PF16908.5 KIY71623.1 - 1.2e-79 267.4 6.2 4.1e-77 259.2 0.5 3.5 4 0 0 4 4 4 2 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 KIY71623.1 - 1e-69 233.9 8.6 1.9e-66 223.3 0.3 3.5 3 0 0 3 3 3 2 Vacuolar-sorting-associated 13 protein C-terminal SHR-BD PF06650.12 KIY71623.1 - 4.9e-61 206.5 0.0 2.2e-57 194.5 0.0 3.4 3 0 0 3 3 3 2 SHR-binding domain of vacuolar-sorting associated protein 13 Chorein_N PF12624.7 KIY71623.1 - 6.6e-28 97.2 5.6 7.9e-28 96.9 0.2 3.4 4 0 0 4 4 4 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 KIY71623.1 - 1.5e-09 38.1 0.0 8.9e-09 35.6 0.0 2.4 3 0 0 3 3 3 1 Autophagy-related protein C terminal domain Apt1 PF10351.9 KIY71623.1 - 0.0014 17.6 0.2 0.33 9.8 0.0 2.5 2 0 0 2 2 2 2 Golgi-body localisation protein domain Cadherin_4 PF17803.1 KIY71623.1 - 1.7 9.3 5.8 1.7 9.3 0.0 3.7 3 0 0 3 3 3 0 Bacterial cadherin-like domain DENN PF02141.21 KIY71624.1 - 8e-19 68.3 0.0 1.5e-18 67.4 0.0 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain Lum_binding PF00677.17 KIY71624.1 - 0.16 11.9 0.0 0.5 10.4 0.0 1.8 1 0 0 1 1 1 0 Lumazine binding domain HsbA PF12296.8 KIY71624.1 - 1.1 9.7 3.5 7.9 6.9 0.2 2.8 3 0 0 3 3 3 0 Hydrophobic surface binding protein A Coatomer_E PF04733.14 KIY71625.1 - 8.3e-41 140.3 0.2 9.6e-41 140.1 0.2 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.6 KIY71625.1 - 0.013 16.0 6.2 0.13 12.8 0.1 4.0 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KIY71625.1 - 0.049 14.3 2.2 17 6.3 0.0 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.14 KIY71625.1 - 0.075 13.7 2.7 12 6.9 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Adaptin_N PF01602.20 KIY71626.1 - 4.5e-120 401.7 5.5 5.8e-120 401.3 5.5 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 KIY71626.1 - 9.1e-39 132.2 0.0 2e-38 131.1 0.0 1.6 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 KIY71626.1 - 2.7e-14 53.4 0.6 6.3e-14 52.2 0.6 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 KIY71626.1 - 0.0024 18.0 2.4 0.074 13.1 0.1 2.7 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 KIY71626.1 - 0.011 15.9 0.5 0.043 14.0 0.5 2.0 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT PF02985.22 KIY71626.1 - 0.012 15.8 0.2 0.42 11.0 0.1 3.4 4 0 0 4 4 4 0 HEAT repeat HEAT_2 PF13646.6 KIY71626.1 - 0.16 12.4 3.7 0.43 11.0 0.8 3.0 2 1 0 2 2 2 0 HEAT repeats HA2 PF04408.23 KIY71627.1 - 1.2e-16 60.9 0.0 3.4e-16 59.5 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KIY71627.1 - 4.9e-14 52.6 0.0 1.2e-13 51.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KIY71627.1 - 2.2e-05 24.3 0.1 9.5e-05 22.2 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.16 KIY71627.1 - 0.0016 18.8 0.5 0.82 10.1 0.0 3.5 3 0 0 3 3 3 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_19 PF13245.6 KIY71627.1 - 0.0023 18.3 0.2 0.0061 16.9 0.2 1.7 1 0 0 1 1 1 1 AAA domain dsrm PF00035.26 KIY71627.1 - 0.0059 17.3 0.0 7.4 7.4 0.0 2.7 2 0 0 2 2 2 2 Double-stranded RNA binding motif ResIII PF04851.15 KIY71627.1 - 0.1 12.6 0.0 0.26 11.3 0.0 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Med12 PF09497.10 KIY71627.1 - 0.15 12.3 0.2 10 6.5 0.0 2.6 2 0 0 2 2 2 0 Transcription mediator complex subunit Med12 Pex24p PF06398.11 KIY71629.1 - 5.7e-10 38.7 0.5 7.7e-10 38.3 0.5 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin HSCB_C PF07743.13 KIY71630.1 - 2.5e-12 47.1 2.4 3.6e-11 43.4 1.4 2.2 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 KIY71630.1 - 4.1e-06 26.8 0.1 8.1e-06 25.9 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain zf-ribbon_3 PF13248.6 KIY71630.1 - 0.0013 18.1 2.6 0.0023 17.3 2.6 1.3 1 0 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_2 PF13240.6 KIY71630.1 - 0.027 14.2 0.5 0.045 13.5 0.5 1.4 1 0 0 1 1 1 0 zinc-ribbon domain DZR PF12773.7 KIY71630.1 - 0.038 14.0 0.1 0.068 13.2 0.1 1.3 1 0 0 1 1 1 0 Double zinc ribbon UPF0547 PF10571.9 KIY71630.1 - 0.15 12.2 2.9 0.32 11.1 2.9 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 zf-C2HC5 PF06221.13 KIY71630.1 - 1.8 8.6 4.7 14 5.8 4.8 2.0 1 1 1 2 2 2 0 Putative zinc finger motif, C2HC5-type Ribosomal_S24e PF01282.19 KIY71631.1 - 6.5e-33 112.5 0.4 1.1e-32 111.7 0.0 1.6 1 1 1 2 2 2 1 Ribosomal protein S24e PEN-2 PF10251.9 KIY71632.1 - 0.031 14.7 1.0 0.049 14.1 1.0 1.4 1 0 0 1 1 1 0 Presenilin enhancer-2 subunit of gamma secretase HEAT PF02985.22 KIY71635.1 - 2.5e-40 133.0 15.5 0.002 18.2 0.1 14.0 15 0 0 15 15 15 10 HEAT repeat HEAT_2 PF13646.6 KIY71635.1 - 1.5e-33 115.1 15.2 1.4e-11 44.6 0.0 8.0 2 2 7 9 9 9 8 HEAT repeats Vac14_Fab1_bd PF12755.7 KIY71635.1 - 3e-12 47.0 0.1 0.0032 18.0 0.0 6.1 3 2 3 6 6 6 4 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 KIY71635.1 - 1.2e-10 41.7 10.7 0.0099 16.4 0.0 8.5 7 3 3 10 10 10 2 HEAT-like repeat Cnd1 PF12717.7 KIY71635.1 - 1.6e-09 38.0 0.4 0.0055 16.8 0.0 4.6 3 1 2 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 KIY71635.1 - 1.3e-06 27.3 2.0 0.00039 19.1 0.2 4.0 2 1 0 4 4 4 1 Adaptin N terminal region Arm PF00514.23 KIY71635.1 - 2e-05 24.4 3.5 2.1 8.5 0.0 6.3 7 0 0 7 7 7 1 Armadillo/beta-catenin-like repeat TAF6_C PF07571.13 KIY71635.1 - 0.00027 21.2 0.5 0.93 9.9 0.0 4.6 3 2 1 4 4 4 1 TAF6 C-terminal HEAT repeat domain CLASP_N PF12348.8 KIY71635.1 - 0.0023 17.5 0.0 4.9 6.6 0.0 3.8 2 1 0 3 3 3 1 CLASP N terminal DRIM PF07539.12 KIY71635.1 - 0.035 12.4 0.8 0.085 11.2 0.8 1.7 1 0 0 1 1 1 0 Down-regulated in metastasis IFRD PF05004.13 KIY71635.1 - 0.15 11.1 0.5 1.8 7.6 0.1 2.7 2 1 0 2 2 2 0 Interferon-related developmental regulator (IFRD) HEAT_PBS PF03130.16 KIY71635.1 - 0.45 11.3 7.2 2.6 9.0 0.6 5.6 5 1 0 5 5 5 0 PBS lyase HEAT-like repeat Aldose_epim PF01263.20 KIY71637.1 - 9.6e-31 107.2 0.0 1.1e-30 107.0 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Actin PF00022.19 KIY71638.1 - 2.6e-129 431.4 0.0 1.2e-128 429.2 0.0 1.7 1 1 0 1 1 1 1 Actin DUF2397 PF09660.10 KIY71640.1 - 0.008 15.1 4.5 0.0091 15.0 4.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2397) SVIP PF15811.5 KIY71640.1 - 0.24 11.9 8.9 0.46 11.0 8.9 1.6 1 1 0 1 1 1 0 Small VCP/p97-interacting protein DUF4813 PF16072.5 KIY71640.1 - 1.8 8.2 14.4 2.1 8.0 14.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) MFS_1 PF07690.16 KIY71641.1 - 1.5e-21 76.7 24.0 1.5e-21 76.7 24.0 1.7 3 0 0 3 3 3 1 Major Facilitator Superfamily MRI PF15325.6 KIY71641.1 - 0.79 10.8 3.5 0.24 12.5 0.5 1.6 2 0 0 2 2 2 0 Modulator of retrovirus infection Sugar_tr PF00083.24 KIY71641.1 - 0.97 8.2 18.6 40 2.9 18.6 2.9 1 1 0 1 1 1 0 Sugar (and other) transporter Ribosomal_L15e PF00827.17 KIY71642.1 - 3e-88 294.6 9.1 3.5e-88 294.4 9.1 1.0 1 0 0 1 1 1 1 Ribosomal L15 DEAD PF00270.29 KIY71644.1 - 2.2e-15 56.9 0.0 4.2e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KIY71644.1 - 1.9e-10 41.0 0.0 7.6e-10 39.0 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KIY71644.1 - 4.2e-06 27.1 0.0 1e-05 25.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CENP-B_dimeris PF09026.10 KIY71644.1 - 0.77 10.2 3.8 2.1 8.8 3.8 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Methyltransf_2 PF00891.18 KIY71645.1 - 1.9e-20 73.0 0.1 1.3e-19 70.3 0.1 2.0 1 1 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 KIY71645.1 - 0.011 15.7 0.0 0.025 14.5 0.0 1.6 1 0 0 1 1 1 0 Dimerisation domain Methyltransf_25 PF13649.6 KIY71645.1 - 0.037 14.7 0.0 0.082 13.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain HTH_IclR PF09339.10 KIY71645.1 - 0.065 13.1 0.3 0.065 13.1 0.3 2.6 3 0 0 3 3 3 0 IclR helix-turn-helix domain RPA_C PF08784.11 KIY71645.1 - 0.066 13.9 0.0 0.15 12.8 0.0 1.6 1 0 0 1 1 1 0 Replication protein A C terminal MarR_2 PF12802.7 KIY71645.1 - 0.087 12.7 0.1 0.63 10.0 0.1 2.2 2 0 0 2 2 2 0 MarR family Dimerisation PF08100.11 KIY71645.1 - 0.14 12.2 0.1 0.36 10.9 0.1 1.7 1 0 0 1 1 1 0 Dimerisation domain PGM_PMM_I PF02878.16 KIY71646.1 - 4.8e-39 133.2 0.0 9.3e-39 132.3 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 KIY71646.1 - 2.4e-20 73.0 0.0 6.4e-20 71.7 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 KIY71646.1 - 1.2e-18 67.3 0.1 5.8e-18 65.1 0.0 2.2 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 KIY71646.1 - 1.4e-05 25.2 0.0 5.6e-05 23.2 0.0 2.0 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Pil1 PF13805.6 KIY71647.1 - 3.1e-21 76.1 0.6 4.3e-21 75.6 0.0 1.4 2 0 0 2 2 2 1 Eisosome component PIL1 DHR10 PF18595.1 KIY71647.1 - 0.033 14.3 1.2 0.19 11.8 1.0 2.3 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain Phage_Nu1 PF07471.12 KIY71647.1 - 0.72 9.6 2.8 0.61 9.8 0.4 1.9 2 0 0 2 2 2 0 Phage DNA packaging protein Nu1 AAA_2 PF07724.14 KIY71648.1 - 4e-50 170.3 0.0 2.1e-45 154.9 0.0 3.5 3 0 0 3 3 3 2 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 KIY71648.1 - 1.7e-32 111.4 2.0 1.7e-32 111.4 2.0 3.1 2 1 1 3 3 3 1 AAA lid domain ClpB_D2-small PF10431.9 KIY71648.1 - 1.3e-26 92.4 0.4 5.4e-26 90.5 0.4 2.2 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 KIY71648.1 - 9.4e-25 87.6 0.0 1.9e-13 51.0 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Clp_N PF02861.20 KIY71648.1 - 1.6e-16 60.2 2.1 1.1e-12 47.9 0.2 3.7 2 1 0 2 2 2 2 Clp amino terminal domain, pathogenicity island component AAA_5 PF07728.14 KIY71648.1 - 3.6e-14 52.9 0.1 2.4e-06 27.6 0.0 4.1 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KIY71648.1 - 1.4e-12 48.3 1.6 1.3e-05 25.6 0.0 4.8 3 2 1 4 4 4 2 AAA ATPase domain AAA_22 PF13401.6 KIY71648.1 - 4.2e-09 36.8 0.1 0.0042 17.4 0.0 4.5 2 2 1 3 3 3 2 AAA domain Sigma54_activat PF00158.26 KIY71648.1 - 7.4e-09 35.5 0.0 1.7e-05 24.6 0.0 2.8 2 1 0 2 2 2 2 Sigma-54 interaction domain IstB_IS21 PF01695.17 KIY71648.1 - 1.6e-07 31.2 0.0 0.00039 20.2 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.21 KIY71648.1 - 6.3e-07 29.0 0.2 0.0033 16.8 0.0 3.0 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 KIY71648.1 - 2.1e-06 27.6 0.0 0.0072 16.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 KIY71648.1 - 2.6e-06 26.9 0.7 0.081 12.1 0.0 3.2 2 1 1 3 3 3 2 TIP49 P-loop domain NACHT PF05729.12 KIY71648.1 - 1e-05 25.5 0.0 0.0032 17.4 0.0 2.5 2 0 0 2 2 2 1 NACHT domain TniB PF05621.11 KIY71648.1 - 0.00011 21.7 0.0 0.15 11.4 0.0 3.7 3 1 0 3 3 2 1 Bacterial TniB protein RNA_helicase PF00910.22 KIY71648.1 - 0.00018 21.8 0.0 1 9.8 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_7 PF12775.7 KIY71648.1 - 0.0002 20.9 0.0 0.42 10.1 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_33 PF13671.6 KIY71648.1 - 0.00027 21.1 0.0 0.33 11.1 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KIY71648.1 - 0.00055 20.5 0.0 0.79 10.3 0.0 3.1 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 KIY71648.1 - 0.00056 19.7 0.0 2.6 7.8 0.0 3.5 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain Zeta_toxin PF06414.12 KIY71648.1 - 0.00086 18.6 0.0 0.14 11.5 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin DnaB_C PF03796.15 KIY71648.1 - 0.0034 16.8 0.0 1.4 8.2 0.0 2.5 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain PhoH PF02562.16 KIY71648.1 - 0.0037 16.8 0.0 0.47 9.9 0.0 2.6 2 0 0 2 2 2 1 PhoH-like protein AAA_30 PF13604.6 KIY71648.1 - 0.0041 16.9 0.0 4.9 6.8 0.0 3.1 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 KIY71648.1 - 0.01 15.8 0.0 4.8 7.2 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Roc PF08477.13 KIY71648.1 - 0.011 16.0 0.0 3 8.1 0.0 3.2 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase Torsin PF06309.11 KIY71648.1 - 0.017 15.2 0.0 0.28 11.3 0.0 2.3 2 0 0 2 2 2 0 Torsin AAA_19 PF13245.6 KIY71648.1 - 0.023 15.0 0.1 4.6 7.6 0.0 3.2 3 0 0 3 3 3 0 AAA domain Sigma54_activ_2 PF14532.6 KIY71648.1 - 0.025 14.7 0.0 12 6.0 0.0 3.3 3 0 0 3 3 3 0 Sigma-54 interaction domain ResIII PF04851.15 KIY71648.1 - 0.04 13.9 0.0 2.4 8.1 0.0 2.9 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit AAA_28 PF13521.6 KIY71648.1 - 0.049 13.9 4.2 4.7 7.4 0.0 3.9 3 1 0 3 3 3 0 AAA domain ATPase PF06745.13 KIY71648.1 - 0.05 12.9 0.0 2.1 7.6 0.0 3.2 3 0 0 3 3 3 0 KaiC ABC_tran PF00005.27 KIY71648.1 - 0.1 13.1 1.7 6.3 7.3 0.0 3.4 4 0 0 4 4 3 0 ABC transporter AAA_3 PF07726.11 KIY71648.1 - 0.1 12.4 0.0 42 4.0 0.0 3.2 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 KIY71648.1 - 0.15 11.6 3.2 15 5.1 0.0 3.5 3 1 0 3 3 3 0 AAA domain ATPase_2 PF01637.18 KIY71648.1 - 0.18 11.7 3.2 13 5.6 0.1 4.0 3 2 1 4 4 3 0 ATPase domain predominantly from Archaea Mg_trans_NIPA PF05653.14 KIY71649.1 - 4.5e-20 72.0 16.7 5.4e-10 38.9 5.0 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA NUDIX PF00293.28 KIY71650.1 - 1.1e-21 77.3 0.0 1.4e-21 76.9 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Rad21_Rec8_N PF04825.13 KIY71651.1 - 7.4e-25 87.3 0.0 1.6e-24 86.1 0.0 1.6 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 KIY71651.1 - 2.3e-11 42.8 0.3 5.9e-11 41.5 0.0 1.8 2 0 0 2 2 2 1 Conserved region of Rad21 / Rec8 like protein ABC2_membrane PF01061.24 KIY71652.1 - 2.3e-63 213.4 53.8 5.9e-33 114.1 14.0 3.1 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KIY71652.1 - 9.9e-35 120.0 0.0 2.9e-18 66.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KIY71652.1 - 1.2e-30 105.2 16.2 4.6e-27 93.7 0.2 3.8 4 0 0 4 4 4 2 CDR ABC transporter ABC_trans_N PF14510.6 KIY71652.1 - 3e-10 40.6 0.5 6.2e-10 39.6 0.5 1.6 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 KIY71652.1 - 1.6e-06 28.6 0.1 0.0018 18.7 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KIY71652.1 - 8.8e-06 26.0 0.0 0.068 13.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KIY71652.1 - 1.4e-05 25.0 0.1 0.00012 22.0 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 KIY71652.1 - 3.2e-05 24.5 0.0 0.26 11.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 KIY71652.1 - 8.3e-05 22.8 0.1 0.27 11.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain cobW PF02492.19 KIY71652.1 - 0.00038 20.1 0.3 0.54 9.8 0.1 3.2 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 KIY71652.1 - 0.00069 19.6 0.0 0.24 11.3 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_25 PF13481.6 KIY71652.1 - 0.0012 18.5 0.5 0.021 14.4 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KIY71652.1 - 0.0019 17.9 0.5 0.23 11.2 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain PduV-EutP PF10662.9 KIY71652.1 - 0.0032 17.2 0.1 4.9 6.9 0.0 2.9 3 0 0 3 3 3 2 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 KIY71652.1 - 0.0042 17.2 0.1 0.74 9.9 0.1 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_28 PF13521.6 KIY71652.1 - 0.0044 17.3 0.0 0.92 9.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 KIY71652.1 - 0.0074 16.7 0.0 4.6 7.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KIY71652.1 - 0.008 16.0 0.0 1.4 8.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system dNK PF01712.19 KIY71652.1 - 0.013 15.3 0.0 0.41 10.5 0.0 2.5 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA_30 PF13604.6 KIY71652.1 - 0.018 14.8 0.6 1.3 8.7 0.6 2.5 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 KIY71652.1 - 0.023 14.2 0.0 1.7 8.1 0.0 2.9 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain ABC2_membrane_3 PF12698.7 KIY71652.1 - 0.057 12.5 43.9 0.007 15.5 24.9 3.3 2 1 0 2 2 2 0 ABC-2 family transporter protein TsaE PF02367.17 KIY71652.1 - 0.092 12.8 0.5 0.58 10.2 0.1 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Rad17 PF03215.15 KIY71652.1 - 0.13 12.2 0.0 18 5.2 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain Septin PF00735.18 KIY71652.1 - 0.15 11.3 0.0 4.4 6.5 0.0 2.3 2 0 0 2 2 2 0 Septin AAA_23 PF13476.6 KIY71652.1 - 0.16 12.5 0.1 0.38 11.2 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KIY71652.1 - 0.19 12.2 0.0 15 6.0 0.0 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF3292 PF11696.8 KIY71653.1 - 1.9e-13 49.7 3.4 1e-07 30.8 0.4 3.5 4 0 0 4 4 4 3 Protein of unknown function (DUF3292) Pex24p PF06398.11 KIY71653.1 - 0.0054 15.8 0.1 1.4 7.9 0.1 2.3 2 0 0 2 2 2 2 Integral peroxisomal membrane peroxin PRT_C PF08372.10 KIY71653.1 - 0.0086 15.8 0.8 0.047 13.5 0.1 2.2 2 0 0 2 2 2 1 Plant phosphoribosyltransferase C-terminal DUF639 PF04842.12 KIY71653.1 - 0.052 13.0 1.1 3.6 7.0 0.3 2.2 2 0 0 2 2 2 0 Plant protein of unknown function (DUF639) Reticulon PF02453.17 KIY71653.1 - 3.1 7.7 7.6 1.6 8.7 1.1 2.3 2 0 0 2 2 2 0 Reticulon F-box-like PF12937.7 KIY71654.1 - 2.1e-10 40.3 0.0 6.7e-10 38.7 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY71654.1 - 0.0023 17.7 2.4 0.012 15.4 2.4 2.2 1 1 0 1 1 1 1 F-box domain DUF2576 PF10845.8 KIY71654.1 - 0.018 14.7 0.0 0.054 13.1 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2576) LRR_4 PF12799.7 KIY71654.1 - 0.61 10.6 6.7 1.1 9.8 0.0 4.0 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) Spore_YpjB PF09577.10 KIY71655.1 - 0.19 11.5 0.0 0.25 11.1 0.0 1.2 1 0 0 1 1 1 0 Sporulation protein YpjB (SpoYpjB) Lipase_3 PF01764.25 KIY71656.1 - 1.1e-20 74.0 0.0 1.6e-20 73.4 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KIY71656.1 - 0.0021 18.7 0.3 0.0043 17.7 0.3 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 KIY71656.1 - 0.0048 16.6 0.0 0.0086 15.8 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.7 KIY71656.1 - 0.015 15.1 0.0 0.028 14.2 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIY71656.1 - 0.028 13.7 0.0 0.05 12.9 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Esterase PF00756.20 KIY71656.1 - 0.04 13.5 0.0 0.34 10.5 0.0 2.3 2 0 0 2 2 2 0 Putative esterase CNH PF00780.22 KIY71657.1 - 3.7e-10 39.9 0.0 1.2e-09 38.2 0.0 1.8 1 1 0 1 1 1 1 CNH domain ANAPC4_WD40 PF12894.7 KIY71658.1 - 0.00041 20.6 0.0 3.6 7.9 0.0 3.4 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KIY71658.1 - 0.00096 19.9 5.4 0.015 16.1 1.2 3.7 4 0 0 4 4 4 1 WD domain, G-beta repeat DUF5595 PF18077.1 KIY71658.1 - 0.054 13.6 0.9 0.1 12.7 0.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5595) SGL PF08450.12 KIY71658.1 - 0.056 13.0 0.0 1 8.9 0.0 2.3 1 1 1 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region BBS2_N PF14781.6 KIY71658.1 - 0.18 11.8 0.0 6.5 6.7 0.0 2.8 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, N-terminal Cation_efflux PF01545.21 KIY71659.1 - 3.2e-48 164.1 20.4 1.3e-47 162.1 20.4 1.8 1 1 0 1 1 1 1 Cation efflux family Tox-GHH2 PF15635.6 KIY71659.1 - 1.8 9.1 10.0 5.6 7.5 1.1 2.4 2 0 0 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin 2 JAB PF01398.21 KIY71660.1 - 2.3e-14 53.4 0.0 3.8e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease HAUS6_N PF14661.6 KIY71660.1 - 0.011 15.3 0.0 0.37 10.3 0.0 2.1 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus DPBB_1 PF03330.18 KIY71661.1 - 8.8e-09 35.5 0.1 1.9e-08 34.4 0.1 1.7 1 1 0 1 1 1 1 Lytic transglycolase Cerato-platanin PF07249.12 KIY71661.1 - 0.027 14.6 0.1 0.051 13.7 0.1 1.5 1 0 0 1 1 1 0 Cerato-platanin GCV_T PF01571.21 KIY71662.1 - 1.1e-81 274.0 0.0 1.4e-81 273.7 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 KIY71662.1 - 9.3e-22 76.8 0.1 2.3e-21 75.5 0.1 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain SnoaL_2 PF12680.7 KIY71663.1 - 0.0024 18.5 0.1 0.0037 17.9 0.1 1.2 1 0 0 1 1 1 1 SnoaL-like domain Ribonuc_red_lgC PF02867.15 KIY71664.1 - 3.8e-180 599.9 0.0 5.1e-180 599.5 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 KIY71664.1 - 2.2e-24 85.2 0.1 7.1e-24 83.6 0.1 1.9 2 0 0 2 2 2 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 KIY71664.1 - 5e-14 52.6 0.4 3.6e-13 49.9 0.0 2.5 2 0 0 2 2 2 1 ATP cone domain DUF2017 PF09438.10 KIY71664.1 - 0.094 12.6 1.1 0.18 11.7 1.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2017) zf-C2H2_jaz PF12171.8 KIY71665.1 - 4.8e-12 45.8 13.7 0.00042 20.5 0.1 4.3 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KIY71665.1 - 1.4e-09 37.9 21.9 0.11 13.4 0.3 5.5 5 0 0 5 5 5 4 C2H2-type zinc finger zf-met PF12874.7 KIY71665.1 - 1.1e-08 35.1 9.7 0.0024 18.2 0.0 3.9 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 KIY71665.1 - 6.3e-06 26.4 19.6 0.16 12.5 0.2 5.4 5 0 0 5 5 5 3 Zinc finger, C2H2 type zinc_ribbon_5 PF13719.6 KIY71665.1 - 0.0013 18.4 0.1 0.0013 18.4 0.1 4.0 5 0 0 5 5 5 1 zinc-ribbon domain zf-C2H2_2 PF12756.7 KIY71665.1 - 0.013 15.8 16.1 0.38 11.1 1.1 2.9 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) DUF4187 PF13821.6 KIY71665.1 - 0.021 14.6 5.3 0.13 12.1 0.4 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4187) FOXP-CC PF16159.5 KIY71665.1 - 0.047 14.3 13.2 1.1 10.0 0.1 3.8 2 2 2 4 4 4 0 FOXP coiled-coil domain DUF2243 PF10002.9 KIY71665.1 - 0.26 11.4 1.1 5.5 7.1 0.3 2.2 1 1 1 2 2 2 0 Predicted membrane protein (DUF2243) CpXC PF14353.6 KIY71665.1 - 0.69 10.0 5.3 1.2 9.2 0.2 2.8 2 1 1 3 3 3 0 CpXC protein zf-RRPl_C4 PF17026.5 KIY71665.1 - 1.1 9.4 10.1 1 9.5 3.6 2.7 1 1 1 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type HypA PF01155.19 KIY71665.1 - 2.9 8.0 9.0 35 4.5 9.0 2.3 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_9 PF14369.6 KIY71665.1 - 3.9 7.8 9.3 1.9 8.8 3.9 3.0 2 1 0 2 2 2 0 zinc-ribbon zf-DBF PF07535.12 KIY71665.1 - 7 6.9 15.4 3.7 7.7 0.5 3.6 2 1 1 3 3 3 0 DBF zinc finger Actin_micro PF17003.5 KIY71665.1 - 9.9 5.2 13.2 0.56 9.3 0.5 2.9 1 1 1 2 2 2 0 Putative actin-like family zf-C2H2_aberr PF17017.5 KIY71666.1 - 0.021 15.0 0.0 0.032 14.4 0.0 1.4 1 0 0 1 1 1 0 Aberrant zinc-finger SnoaL_2 PF12680.7 KIY71668.1 - 0.014 16.0 0.0 0.019 15.6 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like domain DNA_pol_B_thumb PF14791.6 KIY71669.1 - 2.3e-07 30.9 0.1 4.3e-07 30.0 0.1 1.5 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 KIY71669.1 - 9.6e-07 28.5 0.0 2.1e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda DNA_pol_B_palm PF14792.6 KIY71669.1 - 0.00018 21.7 0.0 0.21 11.8 0.0 3.3 2 1 1 3 3 3 2 DNA polymerase beta palm HHH_8 PF14716.6 KIY71669.1 - 0.014 15.8 0.0 0.041 14.2 0.0 1.8 2 0 0 2 2 2 0 Helix-hairpin-helix domain zf-C3HC4_3 PF13920.6 KIY71670.1 - 3.4e-09 36.4 5.8 3.4e-09 36.4 5.8 3.4 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KIY71670.1 - 4.4e-08 32.8 7.9 4.4e-08 32.8 7.9 3.5 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIY71670.1 - 7.2e-08 32.6 8.1 7.2e-08 32.6 8.1 3.4 2 1 1 3 3 3 1 Ring finger domain zf-C2H2_jaz PF12171.8 KIY71670.1 - 7.8e-08 32.4 14.8 0.0016 18.7 0.1 3.7 3 1 1 4 4 3 3 Zinc-finger double-stranded RNA-binding zf-C3HC4 PF00097.25 KIY71670.1 - 2.1e-07 30.7 7.9 2.1e-07 30.7 7.9 3.7 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIY71670.1 - 1e-05 25.4 9.9 1e-05 25.4 9.9 3.3 3 2 0 3 3 3 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KIY71670.1 - 0.00012 22.0 7.4 0.00012 22.0 7.4 3.0 3 0 0 3 3 3 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KIY71670.1 - 0.00014 21.6 8.9 0.00014 21.6 8.9 3.3 3 2 1 4 4 4 1 Prokaryotic RING finger family 4 zf-C2H2_2 PF12756.7 KIY71670.1 - 0.002 18.5 3.9 0.002 18.5 3.9 3.0 2 1 0 3 3 3 1 C2H2 type zinc-finger (2 copies) zf-C3HC4_4 PF15227.6 KIY71670.1 - 0.0024 18.0 8.3 0.0024 18.0 8.3 3.9 3 1 1 4 4 3 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 KIY71670.1 - 0.0026 17.6 8.3 0.011 15.5 8.3 2.2 1 1 0 1 1 1 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 KIY71670.1 - 0.0052 17.1 7.0 0.0052 17.1 7.0 2.6 3 1 0 3 3 3 1 RING-H2 zinc finger domain zf-C2H2 PF00096.26 KIY71670.1 - 0.0053 17.1 0.1 0.0053 17.1 0.1 4.4 5 0 0 5 5 3 2 Zinc finger, C2H2 type zf-met PF12874.7 KIY71670.1 - 0.012 15.9 10.5 0.23 11.9 0.1 4.4 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KIY71670.1 - 0.042 14.7 0.1 0.042 14.7 0.1 5.7 6 0 0 6 6 5 0 C2H2-type zinc finger DUF4187 PF13821.6 KIY71670.1 - 0.044 13.6 8.8 0.77 9.6 0.0 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4187) D5_N PF08706.11 KIY71670.1 - 0.064 13.5 0.1 0.11 12.8 0.1 1.4 1 1 0 1 1 1 0 D5 N terminal like FYVE PF01363.21 KIY71670.1 - 1.8 8.8 19.5 7.2 6.8 3.9 3.7 1 1 2 3 3 3 0 FYVE zinc finger zf-RRPl_C4 PF17026.5 KIY71670.1 - 2.2 8.4 14.5 24 5.1 0.3 3.5 1 1 1 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type Zn_ribbon_17 PF17120.5 KIY71670.1 - 2.7 7.7 11.7 0.36 10.5 4.5 2.8 3 0 0 3 3 3 0 Zinc-ribbon, C4HC2 type Cellulase PF00150.18 KIY71672.1 - 2.5e-07 30.4 0.0 4.4e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF5129 PF17173.4 KIY71672.1 - 0.45 9.6 2.0 0.85 8.7 2.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5129) Secretin_N_2 PF07655.13 KIY71672.1 - 1 10.0 7.6 4.8 7.8 6.5 2.3 2 0 0 2 2 2 0 Secretin N-terminal domain zf-C2H2 PF00096.26 KIY71673.1 - 8.5e-06 25.9 14.2 0.011 16.1 1.3 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIY71673.1 - 4e-05 24.1 12.9 0.23 12.4 1.4 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger Fib_alpha PF08702.10 KIY71673.1 - 0.019 15.1 2.1 0.043 14.0 2.1 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Spc7 PF08317.11 KIY71673.1 - 0.18 10.7 3.4 0.29 10.0 3.4 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein GreA_GreB_N PF03449.15 KIY71673.1 - 2 8.6 6.9 4.4 7.5 6.9 1.6 1 0 0 1 1 1 0 Transcription elongation factor, N-terminal F-box PF00646.33 KIY71674.1 - 3.6e-06 26.7 1.5 7.1e-06 25.8 1.5 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KIY71674.1 - 5.5e-05 23.0 0.6 0.00012 21.9 0.6 1.6 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KIY71674.1 - 0.00027 20.8 0.5 0.0006 19.7 0.5 1.5 1 0 0 1 1 1 1 F-box EF_assoc_2 PF08356.12 KIY71675.1 - 6.2e-35 119.1 0.0 1.5e-34 117.9 0.0 1.7 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.12 KIY71675.1 - 8.4e-32 108.6 0.7 2.1e-31 107.3 0.7 1.7 1 0 0 1 1 1 1 EF hand associated Ras PF00071.22 KIY71675.1 - 3.2e-31 108.1 0.0 1.9e-20 73.1 0.0 2.2 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KIY71675.1 - 5.9e-19 68.5 0.0 9e-11 42.0 0.0 3.1 3 1 0 3 3 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIY71675.1 - 3.4e-08 33.1 0.0 0.0023 17.4 0.0 3.2 2 2 0 2 2 2 2 ADP-ribosylation factor family EF-hand_6 PF13405.6 KIY71675.1 - 4.1e-08 32.5 0.1 0.012 15.5 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 KIY71675.1 - 4.6e-08 32.1 1.7 0.0096 15.4 0.1 2.8 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KIY71675.1 - 1.1e-07 32.2 0.4 0.03 14.8 0.1 3.4 4 1 0 4 4 2 2 EF-hand domain pair MMR_HSR1 PF01926.23 KIY71675.1 - 4.1e-07 30.1 0.0 0.0044 17.1 0.0 2.8 2 1 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.23 KIY71675.1 - 7.8e-06 26.0 1.0 0.058 13.5 0.0 3.1 2 1 0 3 3 3 1 Dynamin family AAA_22 PF13401.6 KIY71675.1 - 7.9e-06 26.2 0.1 0.059 13.6 0.0 3.1 2 2 1 3 3 2 2 AAA domain AAA_16 PF13191.6 KIY71675.1 - 8e-06 26.3 0.1 0.096 13.1 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain Septin PF00735.18 KIY71675.1 - 1.7e-05 24.2 0.0 0.042 13.1 0.0 2.3 2 0 0 2 2 2 2 Septin RsgA_GTPase PF03193.16 KIY71675.1 - 5.8e-05 23.1 0.1 0.29 11.0 0.0 3.4 4 0 0 4 4 3 1 RsgA GTPase ABC_tran PF00005.27 KIY71675.1 - 6.2e-05 23.5 0.0 0.32 11.5 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_18 PF13238.6 KIY71675.1 - 6.9e-05 23.4 0.0 0.035 14.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KIY71675.1 - 7e-05 22.8 0.0 0.2 11.6 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA_29 PF13555.6 KIY71675.1 - 9.5e-05 22.1 0.0 0.079 12.7 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_7 PF12775.7 KIY71675.1 - 0.00015 21.3 0.0 0.057 12.9 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_33 PF13671.6 KIY71675.1 - 0.00019 21.6 0.0 0.95 9.6 0.0 2.9 3 0 0 3 3 2 2 AAA domain EF-hand_5 PF13202.6 KIY71675.1 - 0.00021 20.6 2.8 0.43 10.2 0.4 2.9 2 0 0 2 2 2 2 EF hand SRPRB PF09439.10 KIY71675.1 - 0.00032 20.2 0.0 0.43 10.0 0.0 2.6 2 1 0 2 2 2 2 Signal recognition particle receptor beta subunit AAA_24 PF13479.6 KIY71675.1 - 0.00038 20.3 0.0 0.64 9.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 KIY71675.1 - 0.00045 20.7 0.0 0.16 12.4 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) EF-hand_10 PF14788.6 KIY71675.1 - 0.0007 19.4 0.9 0.26 11.2 0.0 2.4 2 0 0 2 2 2 1 EF hand VirE PF05272.11 KIY71675.1 - 0.00078 19.2 0.0 0.39 10.4 0.0 2.8 3 0 0 3 3 2 1 Virulence-associated protein E RNA_helicase PF00910.22 KIY71675.1 - 0.00086 19.7 0.0 0.64 10.4 0.0 2.5 2 0 0 2 2 2 1 RNA helicase ATP_bind_1 PF03029.17 KIY71675.1 - 0.0014 18.4 1.3 9 6.0 0.1 4.0 4 0 0 4 4 4 0 Conserved hypothetical ATP binding protein G-alpha PF00503.20 KIY71675.1 - 0.0024 17.1 0.0 2 7.5 0.0 2.6 3 0 0 3 3 3 2 G-protein alpha subunit NB-ARC PF00931.22 KIY71675.1 - 0.0036 16.5 0.0 1.3 8.1 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain DUF815 PF05673.13 KIY71675.1 - 0.0048 16.1 0.1 0.38 9.9 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) FtsK_SpoIIIE PF01580.18 KIY71675.1 - 0.0071 15.7 0.1 1.2 8.4 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_28 PF13521.6 KIY71675.1 - 0.011 16.0 0.0 6.5 7.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain MCM PF00493.23 KIY71675.1 - 0.012 14.7 0.0 0.11 11.5 0.0 2.1 2 0 0 2 2 2 0 MCM P-loop domain AAA_14 PF13173.6 KIY71675.1 - 0.013 15.5 0.0 2 8.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KIY71675.1 - 0.013 15.1 0.0 0.56 9.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 KIY71675.1 - 0.014 15.2 0.0 0.56 9.9 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_23 PF13476.6 KIY71675.1 - 0.014 15.9 0.1 5.2 7.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain SPARC_Ca_bdg PF10591.9 KIY71675.1 - 0.016 15.6 0.7 3.3 8.1 0.0 2.8 3 0 0 3 3 2 0 Secreted protein acidic and rich in cysteine Ca binding region TsaE PF02367.17 KIY71675.1 - 0.017 15.1 0.0 3.8 7.5 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Ploopntkinase3 PF18751.1 KIY71675.1 - 0.018 15.0 0.0 2.2 8.2 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 cobW PF02492.19 KIY71675.1 - 0.02 14.5 0.1 1.3 8.6 0.0 2.9 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.14 KIY71675.1 - 0.023 14.7 0.0 0.45 10.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NOG1 PF06858.14 KIY71675.1 - 0.027 14.3 0.2 2.7 7.8 0.1 2.8 2 0 0 2 2 2 0 Nucleolar GTP-binding protein 1 (NOG1) Pox_A32 PF04665.12 KIY71675.1 - 0.028 13.9 0.0 7.7 5.9 0.0 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein TniB PF05621.11 KIY71675.1 - 0.028 13.8 0.0 6 6.2 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein PduV-EutP PF10662.9 KIY71675.1 - 0.034 13.9 0.0 6.6 6.5 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATPase_2 PF01637.18 KIY71675.1 - 0.05 13.5 0.1 0.65 9.9 0.0 2.6 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea Zeta_toxin PF06414.12 KIY71675.1 - 0.055 12.7 0.0 5.5 6.2 0.0 2.5 3 0 0 3 3 2 0 Zeta toxin AAA_15 PF13175.6 KIY71675.1 - 0.1 12.3 0.0 7.8 6.1 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain ATP-synt_ab PF00006.25 KIY71675.1 - 0.11 12.2 0.0 3.6 7.2 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Sigma54_activat PF00158.26 KIY71675.1 - 0.11 12.1 0.0 3.7 7.2 0.0 2.7 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_30 PF13604.6 KIY71675.1 - 0.12 12.0 0.0 3.9 7.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 KIY71675.1 - 0.19 10.6 0.0 15 4.4 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Rad17 PF03215.15 KIY71675.1 - 0.19 11.6 0.0 1.9 8.4 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain AIG1 PF04548.16 KIY71675.1 - 0.2 11.0 0.0 0.4 10.0 0.0 1.5 1 0 0 1 1 1 0 AIG1 family Guanylate_kin PF00625.21 KIY71675.1 - 0.21 11.3 0.1 1.2 8.8 0.1 2.1 2 0 0 2 2 2 0 Guanylate kinase MobB PF03205.14 KIY71675.1 - 0.21 11.5 0.1 21 5.0 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B VWA PF00092.28 KIY71676.1 - 2.6e-07 31.0 0.0 5.1e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KIY71676.1 - 1.9e-06 28.5 0.0 4.5e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain Tet_res_leader PF08050.12 KIY71676.1 - 0.052 13.4 0.1 0.052 13.4 0.1 1.7 2 0 0 2 2 2 0 Tetracycline resistance leader peptide Integrin_beta PF00362.18 KIY71676.1 - 0.19 11.4 0.0 0.37 10.4 0.0 1.4 1 0 0 1 1 1 0 Integrin beta chain VWA domain Aldo_ket_red PF00248.21 KIY71678.1 - 3.2e-72 243.2 0.0 3.9e-72 242.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Response_reg PF00072.24 KIY71679.1 - 4.2e-21 75.2 0.0 8.7e-21 74.2 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 KIY71679.1 - 6.6e-17 62.0 0.1 1.9e-16 60.6 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KIY71679.1 - 5.4e-14 52.0 0.0 1.3e-13 50.8 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF PF01590.26 KIY71679.1 - 1.4e-09 38.6 0.0 2.8e-06 28.0 0.0 3.2 2 1 0 2 2 2 2 GAF domain Nucleocap_ssRNA PF11128.8 KIY71679.1 - 0.023 14.4 0.0 0.047 13.4 0.0 1.4 1 0 0 1 1 1 0 Plant viral coat protein nucleocapsid DUF2802 PF10975.8 KIY71679.1 - 0.21 11.7 0.0 0.51 10.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2802) zf-H2C2_5 PF13909.6 KIY71680.1 - 2.1e-15 56.2 9.8 1.4e-06 27.9 0.8 3.3 3 0 0 3 3 3 3 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 KIY71680.1 - 3e-11 43.1 15.7 8.8e-05 22.8 0.8 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIY71680.1 - 1.3e-08 34.9 11.4 0.054 14.3 0.2 3.3 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KIY71680.1 - 5.9e-08 32.8 2.1 0.00014 22.2 0.1 3.6 4 0 0 4 4 4 2 Zinc-finger double domain zf-Di19 PF05605.12 KIY71680.1 - 5.6e-06 26.6 5.6 0.0042 17.3 1.9 2.7 2 1 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_11 PF16622.5 KIY71680.1 - 0.00072 19.3 0.8 1.4 8.7 0.0 2.6 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-C2H2_9 PF16293.5 KIY71680.1 - 0.0018 18.1 4.0 0.064 13.1 0.1 3.0 1 1 2 3 3 3 2 C2H2 type zinc-finger (1 copy) zf-C2H2_2 PF12756.7 KIY71680.1 - 0.047 14.0 6.1 5.5 7.4 0.1 2.9 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) Vps36-NZF-N PF16988.5 KIY71680.1 - 0.26 10.7 1.9 0.77 9.2 0.5 2.4 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zinc_ribbon_15 PF17032.5 KIY71680.1 - 0.27 12.0 3.4 2.3 9.1 1.0 2.2 1 1 0 2 2 2 0 zinc-ribbon family zf_C2H2_ZHX PF18387.1 KIY71680.1 - 0.36 10.5 3.3 0.39 10.4 0.0 2.5 1 1 2 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain OrsD PF12013.8 KIY71680.1 - 0.36 11.3 6.4 1.6 9.2 0.7 2.8 1 1 2 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D zinc_ribbon_9 PF14369.6 KIY71680.1 - 0.58 10.5 8.1 19 5.6 0.1 3.5 4 0 0 4 4 4 0 zinc-ribbon zf-UDP PF14569.6 KIY71680.1 - 1.1 9.4 5.3 25 5.1 5.2 2.6 1 1 0 1 1 1 0 Zinc-binding RING-finger zf-BED PF02892.15 KIY71680.1 - 4.2 7.5 8.2 0.39 10.8 1.0 2.5 1 1 1 2 2 2 0 BED zinc finger MOZ_SAS PF01853.18 KIY71683.1 - 1.2e-66 223.8 0.1 1.8e-66 223.2 0.1 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KIY71683.1 - 3e-22 78.0 1.7 8.8e-22 76.5 1.7 1.9 1 0 0 1 1 1 1 MYST family zinc finger domain PHD PF00628.29 KIY71683.1 - 5.3e-08 32.6 13.4 1.3e-07 31.4 8.9 2.5 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 KIY71683.1 - 0.00053 19.5 6.9 0.002 17.6 3.1 2.6 2 0 0 2 2 2 1 PHD-finger PHF5 PF03660.14 KIY71683.1 - 0.0067 16.6 2.8 0.016 15.4 2.8 1.6 1 0 0 1 1 1 1 PHF5-like protein Prok-RING_1 PF14446.6 KIY71683.1 - 0.0087 16.0 2.3 0.024 14.6 2.3 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 Acetyltransf_7 PF13508.7 KIY71683.1 - 0.062 13.7 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain zf-Sec23_Sec24 PF04810.15 KIY71683.1 - 2.2 8.4 5.3 1 9.5 0.1 2.9 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger FXR_C1 PF16096.5 KIY71684.1 - 0.46 10.7 3.8 0.78 10.0 3.8 1.4 1 0 0 1 1 1 0 Fragile X-related 1 protein C-terminal region 2 DnaJ_C PF01556.18 KIY71685.1 - 2.9e-37 128.0 0.1 4e-37 127.6 0.1 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KIY71685.1 - 3.2e-18 65.6 0.9 5.2e-18 64.9 0.9 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KIY71685.1 - 1.3e-12 47.9 16.5 2.2e-12 47.2 16.5 1.4 1 0 0 1 1 1 1 DnaJ central domain Cytochrome_C7 PF14522.6 KIY71685.1 - 0.0002 21.3 7.3 0.04 13.9 0.7 2.3 2 0 0 2 2 2 2 Cytochrome c7 and related cytochrome c Cytochrom_c3_2 PF14537.6 KIY71685.1 - 0.0017 18.8 9.4 0.0083 16.6 9.4 2.1 1 1 0 1 1 1 1 Cytochrome c3 Anti-TRAP PF15777.5 KIY71685.1 - 0.0097 15.8 10.0 0.42 10.6 2.1 2.6 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein Cytochrom_CIII PF02085.16 KIY71685.1 - 0.014 15.7 7.9 0.027 14.8 7.5 1.6 1 1 0 1 1 1 0 Class III cytochrome C family Cytochrome_C554 PF13435.6 KIY71685.1 - 0.049 14.5 6.6 1.8 9.5 0.2 3.0 3 0 0 3 3 3 0 Cytochrome c554 and c-prime HypA PF01155.19 KIY71685.1 - 0.18 11.8 7.7 4 7.5 0.3 2.2 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-RING_10 PF16685.5 KIY71685.1 - 3 8.0 7.0 1 9.5 3.4 1.9 1 1 1 2 2 2 0 zinc RING finger of MSL2 DUF1924 PF09086.11 KIY71685.1 - 4.1 7.8 6.5 11 6.5 1.5 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF1924) Methyltr_RsmB-F PF01189.17 KIY71686.1 - 6.5e-28 97.7 0.0 9.7e-28 97.2 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Fibrillarin PF01269.17 KIY71686.1 - 0.016 14.3 0.0 0.028 13.5 0.0 1.3 1 0 0 1 1 1 0 Fibrillarin FtsJ PF01728.19 KIY71686.1 - 0.14 12.2 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase TPP_enzyme_N PF02776.18 KIY71687.1 - 5.1e-35 120.6 0.1 7.5e-35 120.1 0.1 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 KIY71687.1 - 3e-16 59.4 0.0 1.4e-15 57.2 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 KIY71687.1 - 1.2e-14 54.3 0.0 3e-13 49.8 0.0 2.4 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DUF362 PF04015.12 KIY71687.1 - 0.13 12.4 0.0 0.35 11.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF362) PROCN PF08083.11 KIY71688.1 - 1e-232 772.1 8.6 1e-232 772.1 8.6 1.7 2 0 0 2 2 2 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 KIY71688.1 - 3.5e-126 419.4 0.6 6.2e-126 418.6 0.6 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 KIY71688.1 - 1.2e-87 291.9 2.3 1.2e-87 291.9 2.3 2.1 2 0 0 2 2 2 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 KIY71688.1 - 2.7e-84 280.6 4.4 2.9e-84 280.5 2.2 2.3 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 KIY71688.1 - 3.4e-73 244.0 0.1 6.6e-73 243.1 0.1 1.5 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.9 KIY71688.1 - 8.2e-46 154.3 0.2 1.8e-45 153.2 0.2 1.6 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.11 KIY71688.1 - 2.7e-42 143.6 0.0 5.7e-42 142.5 0.0 1.6 1 0 0 1 1 1 1 PROCT (NUC072) domain JAB PF01398.21 KIY71688.1 - 0.011 15.7 0.0 0.023 14.7 0.0 1.5 1 0 0 1 1 1 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Abhydrolase_6 PF12697.7 KIY71689.1 - 2.4e-12 48.0 0.0 2.9e-12 47.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIY71689.1 - 1.8e-08 33.9 0.0 2.3e-07 30.4 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KIY71689.1 - 0.033 13.8 0.0 0.93 9.1 0.0 2.1 1 1 0 2 2 2 0 alpha/beta hydrolase fold SIKE PF05769.11 KIY71690.1 - 2.2e-05 24.5 12.2 0.0029 17.6 4.0 2.5 2 1 0 2 2 2 2 SIKE family Cnn_1N PF07989.11 KIY71690.1 - 0.0047 17.0 7.2 0.11 12.7 0.3 3.0 3 0 0 3 3 3 2 Centrosomin N-terminal motif 1 Nsp1_C PF05064.13 KIY71690.1 - 0.074 12.9 3.9 0.27 11.0 0.1 2.6 2 1 0 2 2 2 0 Nsp1-like C-terminal region YabA PF06156.13 KIY71690.1 - 0.1 13.3 9.5 1.3 9.7 3.0 3.0 2 1 1 3 3 3 0 Initiation control protein YabA NYD-SP28_assoc PF14775.6 KIY71690.1 - 1.1 9.4 12.6 3.3 7.9 1.3 3.1 3 0 0 3 3 3 0 Sperm tail C-terminal domain OmpH PF03938.14 KIY71690.1 - 5.3 7.4 7.9 0.49 10.7 1.0 2.1 1 1 0 2 2 2 0 Outer membrane protein (OmpH-like) Fungal_trans PF04082.18 KIY71692.1 - 5.8e-12 45.2 0.1 1e-11 44.4 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY71692.1 - 1.3e-08 34.8 11.2 2.5e-08 33.9 11.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HAD_2 PF13419.6 KIY71693.1 - 1.7e-06 28.2 0.0 0.037 14.1 0.0 2.4 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KIY71693.1 - 0.0015 18.9 0.0 0.0084 16.4 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Peptidase_C65 PF10275.9 KIY71694.1 - 1.2e-68 231.2 0.0 1.5e-68 231.0 0.0 1.0 1 0 0 1 1 1 1 Peptidase C65 Otubain DUF4224 PF13986.6 KIY71694.1 - 0.014 15.3 0.0 0.044 13.7 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4224) OTU PF02338.19 KIY71694.1 - 0.022 15.3 0.0 5.3 7.5 0.0 2.3 2 0 0 2 2 2 0 OTU-like cysteine protease RRM_1 PF00076.22 KIY71698.1 - 1e-72 239.9 0.1 5.9e-19 67.7 0.0 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KIY71698.1 - 1e-05 25.3 0.0 0.021 14.7 0.0 3.9 4 0 0 4 4 4 1 Occluded RNA-recognition motif PHM7_cyt PF14703.6 KIY71698.1 - 0.00045 20.5 6.6 21 5.3 0.0 6.9 6 3 2 8 8 8 0 Cytosolic domain of 10TM putative phosphate transporter Prim-Pol PF09250.11 KIY71698.1 - 0.00093 19.6 0.0 0.0038 17.6 0.0 2.0 2 0 0 2 2 2 1 Bifunctional DNA primase/polymerase, N-terminal Nup35_RRM_2 PF14605.6 KIY71698.1 - 0.0037 17.2 0.0 17 5.5 0.0 4.0 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif DUF5560 PF17715.1 KIY71698.1 - 0.015 14.7 0.9 0.034 13.6 0.9 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5560) RRM_3 PF08777.11 KIY71698.1 - 0.035 14.1 0.1 18 5.4 0.0 4.2 5 1 0 5 5 5 0 RNA binding motif DUF2491 PF10679.9 KIY71698.1 - 0.069 12.3 0.2 0.15 11.3 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2491) LETM1 PF07766.13 KIY71698.1 - 0.1 11.9 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 LETM1-like protein DUF5449 PF17528.2 KIY71698.1 - 0.16 11.7 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5449) Isochorismatase PF00857.20 KIY71699.1 - 1.9e-19 70.5 0.0 5.8e-19 68.9 0.0 1.8 1 1 0 1 1 1 1 Isochorismatase family SLATT_fungal PF18142.1 KIY71700.1 - 0.35 10.8 0.8 0.76 9.8 0.1 1.7 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain IU_nuc_hydro PF01156.19 KIY71701.1 - 3.1e-76 256.9 0.1 3.9e-76 256.6 0.1 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase GF_recep_IV PF14843.6 KIY71701.1 - 0.13 12.0 0.5 0.26 11.1 0.5 1.4 1 0 0 1 1 1 0 Growth factor receptor domain IV IU_nuc_hydro PF01156.19 KIY71702.1 - 1.8e-82 277.3 0.1 2.2e-82 277.1 0.1 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase SARA PF11409.8 KIY71702.1 - 0.13 12.5 0.9 0.29 11.4 0.9 1.6 1 0 0 1 1 1 0 Smad anchor for receptor activation (SARA) ICL PF00463.21 KIY71703.1 - 2.3e-257 854.7 0.3 2.7e-257 854.5 0.3 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 KIY71703.1 - 1.5e-07 31.1 0.0 3e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Glycos_transf_4 PF00953.21 KIY71704.1 - 1.5e-29 103.0 8.5 1.5e-29 103.0 8.5 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 4 PLDc PF00614.22 KIY71705.1 - 4.7e-13 48.7 0.7 1.5e-05 24.9 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 KIY71705.1 - 6.1e-13 48.8 0.0 3.5e-06 27.0 0.0 2.6 2 0 0 2 2 2 2 PLD-like domain PX PF00787.24 KIY71705.1 - 8e-12 45.1 3.9 3.5e-09 36.6 0.5 3.7 4 0 0 4 4 4 2 PX domain FAD_binding_2 PF00890.24 KIY71706.1 - 2.5e-40 138.8 0.5 2e-39 135.9 0.5 1.9 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KIY71706.1 - 2.5e-11 43.6 0.5 7.9e-07 28.8 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIY71706.1 - 1.4e-07 31.1 0.1 0.0046 16.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KIY71706.1 - 5e-06 25.5 3.8 0.067 11.9 0.0 3.3 3 0 0 3 3 3 2 HI0933-like protein GIDA PF01134.22 KIY71706.1 - 2.5e-05 23.5 5.4 0.00085 18.5 0.2 3.1 3 0 0 3 3 3 1 Glucose inhibited division protein A DAO PF01266.24 KIY71706.1 - 4.3e-05 23.2 10.2 0.01 15.5 0.2 3.0 3 0 0 3 3 3 2 FAD dependent oxidoreductase GMC_oxred_N PF00732.19 KIY71706.1 - 0.0011 18.4 0.1 0.014 14.8 0.0 2.4 2 1 1 3 3 3 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KIY71706.1 - 0.045 14.0 0.7 0.13 12.5 0.0 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KIY71706.1 - 0.065 13.8 0.3 0.46 11.1 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.21 KIY71707.1 - 2.5e-29 102.4 0.1 3.4e-29 101.9 0.1 1.1 1 0 0 1 1 1 1 ThiF family DUF3080 PF11279.8 KIY71707.1 - 0.012 14.9 0.2 0.018 14.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3080) Glycos_transf_3 PF00591.21 KIY71707.1 - 0.042 13.5 0.1 0.52 9.9 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase family, a/b domain E1_4HB PF16191.5 KIY71707.1 - 0.048 13.9 0.0 0.091 13.0 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-activating enzyme E1 four-helix bundle Fungal_trans PF04082.18 KIY71708.1 - 8.5e-21 74.2 0.0 1.3e-20 73.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY71708.1 - 3.8e-08 33.3 9.6 6.2e-08 32.6 9.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PPR_2 PF13041.6 KIY71709.1 - 4.8e-06 26.7 0.0 0.0042 17.3 0.0 4.7 4 1 1 5 5 5 1 PPR repeat family PPR_long PF17177.4 KIY71709.1 - 0.00038 19.9 0.0 0.00091 18.6 0.0 1.7 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 KIY71709.1 - 0.0012 19.0 0.4 21 5.6 0.0 5.6 6 0 0 6 6 6 1 PPR repeat PPR_3 PF13812.6 KIY71709.1 - 0.0082 16.2 0.0 0.031 14.3 0.0 1.9 2 0 0 2 2 2 1 Pentatricopeptide repeat domain GRASP55_65 PF04495.14 KIY71710.1 - 1.2e-54 184.4 0.0 1.6e-37 128.9 0.0 2.0 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_6 PF17820.1 KIY71710.1 - 1.3e-05 25.0 0.0 0.00046 20.0 0.0 2.8 3 0 0 3 3 3 1 PDZ domain PDZ_2 PF13180.6 KIY71710.1 - 0.0007 19.9 0.0 0.36 11.2 0.0 2.2 2 0 0 2 2 2 2 PDZ domain RhgB_N PF09284.10 KIY71711.1 - 2.2e-93 312.4 1.0 2.2e-93 312.4 1.0 1.9 2 0 0 2 2 2 1 Rhamnogalacturonan lyase B, N-terminal CBM-like PF14683.6 KIY71711.1 - 1.6e-40 138.7 0.1 7.2e-40 136.6 0.0 2.1 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.6 KIY71711.1 - 1.6e-16 59.9 2.8 2.3e-16 59.3 1.7 2.0 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.6 KIY71711.1 - 0.0011 19.2 1.0 0.0011 19.2 1.0 2.1 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain RRM_1 PF00076.22 KIY71712.1 - 2.6e-49 164.9 0.2 7e-18 64.2 0.0 6.0 6 0 0 6 6 6 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KIY71712.1 - 5.5e-06 26.1 0.0 4.2 7.3 0.0 4.5 4 0 0 4 4 4 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 KIY71712.1 - 5e-05 23.2 0.0 2.3 8.3 0.0 3.8 3 0 0 3 3 3 3 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 KIY71712.1 - 0.01 15.9 0.0 18 5.6 0.0 3.9 3 1 0 3 3 3 0 RNA recognition motif Suf PF05843.14 KIY71712.1 - 0.046 13.7 0.1 0.046 13.7 0.1 3.4 3 1 1 4 4 4 0 Suppressor of forked protein (Suf) TPR_2 PF07719.17 KIY71712.1 - 7.5 6.9 6.6 60 4.1 3.5 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat F-box-like PF12937.7 KIY71713.1 - 1.4e-09 37.6 0.6 1.4e-09 37.6 0.6 2.6 2 1 1 3 3 3 1 F-box-like AlaDh_PNT_N PF05222.15 KIY71714.1 - 8e-28 97.4 0.0 1.2e-27 96.9 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 KIY71714.1 - 0.018 14.3 0.0 0.081 12.2 0.0 2.0 1 1 1 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain DUF5060 PF16586.5 KIY71714.1 - 0.11 12.8 0.0 1 9.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5060) NmrA PF05368.13 KIY71715.1 - 5.4e-20 71.9 0.3 6.9e-20 71.6 0.3 1.1 1 0 0 1 1 1 1 NmrA-like family F420_oxidored PF03807.17 KIY71715.1 - 0.00016 22.2 0.1 0.001 19.6 0.0 2.4 2 1 1 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 KIY71715.1 - 0.00021 21.2 0.2 0.00037 20.4 0.2 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KIY71715.1 - 0.0004 20.6 0.1 0.00065 20.0 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 KIY71715.1 - 0.0018 18.5 0.1 0.0034 17.6 0.1 1.5 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_2 PF03446.15 KIY71715.1 - 0.0018 18.5 0.1 0.0028 17.8 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 KIY71715.1 - 0.0084 16.2 0.1 0.014 15.4 0.1 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Shikimate_DH PF01488.20 KIY71715.1 - 0.013 15.6 0.0 0.02 14.9 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 KIY71715.1 - 0.016 15.6 0.1 0.026 15.0 0.1 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Epimerase PF01370.21 KIY71715.1 - 0.016 14.6 0.0 0.024 14.1 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short PF00106.25 KIY71715.1 - 0.077 12.4 0.1 0.11 12.0 0.1 1.3 1 0 0 1 1 1 0 short chain dehydrogenase 2-Hacid_dh_C PF02826.19 KIY71715.1 - 0.078 12.3 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Alpha-amylase PF00128.24 KIY71716.1 - 8.4e-56 189.9 1.2 1.2e-55 189.4 1.2 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.11 KIY71716.1 - 1.3e-13 51.0 0.0 2.7e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) Iwr1 PF08574.10 KIY71718.1 - 4.8e-12 46.7 8.8 4.8e-12 46.7 8.8 2.1 2 0 0 2 2 2 1 Transcription factor Iwr1 Pectate_lyase_3 PF12708.7 KIY71719.1 - 2e-92 308.9 24.7 1.3e-82 276.8 10.7 3.0 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 KIY71719.1 - 7.7e-08 31.9 2.3 0.0028 17.3 0.2 3.1 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase FAD_binding_4 PF01565.23 KIY71720.1 - 1.7e-26 92.6 2.4 1.3e-25 89.7 1.6 2.3 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 KIY71720.1 - 3.2e-06 27.2 0.2 7e-06 26.0 0.2 1.6 1 0 0 1 1 1 1 Berberine and berberine like Fez1 PF06818.15 KIY71721.1 - 0.72 10.3 31.8 0.1 13.0 12.6 3.5 2 1 1 3 3 3 0 Fez1 DUF4407 PF14362.6 KIY71721.1 - 1.9 7.8 22.7 1.4e+02 1.6 22.0 2.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) CsbD PF05532.12 KIY71722.1 - 0.14 12.1 0.2 0.3 11.0 0.2 1.5 1 0 0 1 1 1 0 CsbD-like SET PF00856.28 KIY71723.1 - 1.7e-10 41.6 0.0 7.5e-09 36.2 0.0 2.3 1 1 0 1 1 1 1 SET domain dCMP_cyt_deam_1 PF00383.23 KIY71723.1 - 3.4e-07 30.1 0.0 5.8e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KIY71723.1 - 0.00021 21.1 0.0 0.00037 20.2 0.0 1.5 1 0 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 KIY71723.1 - 0.03 14.4 0.1 0.056 13.5 0.1 1.4 1 0 0 1 1 1 0 Bd3614-like deaminase F-actin_cap_A PF01267.17 KIY71724.1 - 5.3e-99 331.0 0.0 6e-99 330.8 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit NAD_binding_10 PF13460.6 KIY71725.1 - 0.0006 19.7 0.7 0.0013 18.6 0.6 1.5 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KIY71725.1 - 0.018 14.6 0.1 0.027 14.0 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family Peptidase_C48 PF02902.19 KIY71726.1 - 1.7e-24 86.9 0.0 1e-13 51.7 0.0 2.8 2 1 0 2 2 2 2 Ulp1 protease family, C-terminal catalytic domain Mur_ligase_M PF08245.12 KIY71727.1 - 4.9e-07 29.9 0.0 1.7e-06 28.2 0.0 2.0 1 1 0 1 1 1 1 Mur ligase middle domain adh_short_C2 PF13561.6 KIY71729.1 - 2.7e-41 141.7 0.6 6.9e-40 137.1 0.6 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIY71729.1 - 1.4e-37 129.1 1.6 2.4e-37 128.3 1.6 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIY71729.1 - 6.1e-06 26.3 0.9 1.9e-05 24.7 0.2 1.9 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KIY71729.1 - 0.055 12.9 0.7 0.36 10.2 0.7 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Pyr_redox PF00070.27 KIY71729.1 - 0.26 11.9 1.2 3.5 8.2 0.7 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SKN1 PF03935.15 KIY71730.1 - 5.9e-199 661.6 7.0 6.8e-199 661.4 7.0 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Homeobox_KN PF05920.11 KIY71731.1 - 5.3e-15 55.0 0.0 7.1e-15 54.6 0.0 1.2 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 KIY71731.1 - 3e-06 27.0 0.0 3.7e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Homeodomain Ish1 PF10281.9 KIY71731.1 - 0.075 13.4 0.2 0.13 12.6 0.2 1.4 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein Baculo_E66 PF04850.12 KIY71732.1 - 0.21 10.4 0.0 0.21 10.3 0.0 1.1 1 0 0 1 1 1 0 Baculovirus E66 occlusion-derived virus envelope protein EB PF01683.18 KIY71733.1 - 0.00029 21.1 25.9 0.046 14.0 7.9 4.1 2 1 2 4 4 4 2 EB module Dickkopf_N PF04706.12 KIY71733.1 - 0.14 12.6 27.7 3 8.4 7.6 3.5 3 0 0 3 3 3 0 Dickkopf N-terminal cysteine-rich region LapA_dom PF06305.11 KIY71733.1 - 0.15 11.9 0.3 0.24 11.2 0.3 1.2 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain PIG-X PF08320.12 KIY71734.1 - 3.3e-29 102.3 0.1 4.5e-29 101.9 0.1 1.2 1 0 0 1 1 1 1 PIG-X / PBN1 fn3_PAP PF17808.1 KIY71734.1 - 0.13 12.4 0.0 7.4 6.7 0.0 2.1 1 1 1 2 2 2 0 Fn3-like domain from Purple Acid Phosphatase adh_short PF00106.25 KIY71735.1 - 1.6e-49 168.0 0.0 2.2e-49 167.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIY71735.1 - 4.4e-41 141.0 0.0 5.4e-41 140.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIY71735.1 - 3.2e-10 40.2 0.0 6.6e-10 39.2 0.0 1.6 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 KIY71735.1 - 2.2e-05 24.0 0.0 3.4e-05 23.3 0.0 1.4 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 KIY71735.1 - 0.011 15.2 0.0 0.023 14.1 0.0 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family HATPase_c PF02518.26 KIY71736.1 - 5e-23 81.7 0.0 9e-23 80.9 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PHY PF00360.20 KIY71736.1 - 7.4e-21 74.3 0.0 1.4e-20 73.4 0.0 1.4 1 0 0 1 1 1 1 Phytochrome region Response_reg PF00072.24 KIY71736.1 - 6.4e-15 55.3 0.0 4.4e-14 52.6 0.0 2.1 1 1 0 1 1 1 1 Response regulator receiver domain GAF PF01590.26 KIY71736.1 - 2.1e-13 51.1 0.1 5e-13 49.8 0.1 1.7 1 0 0 1 1 1 1 GAF domain HisKA PF00512.25 KIY71736.1 - 2.8e-11 43.3 1.0 6.7e-11 42.1 1.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_2 PF08446.11 KIY71736.1 - 5.5e-05 23.8 0.0 0.00023 21.8 0.0 2.1 2 0 0 2 2 2 1 PAS fold HATPase_c_3 PF13589.6 KIY71736.1 - 0.15 11.9 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase F-box-like PF12937.7 KIY71737.1 - 1.5e-06 28.0 0.1 5.7e-06 26.1 0.0 2.1 2 1 0 2 2 2 1 F-box-like Con-6 PF10346.9 KIY71739.1 - 9.7e-40 134.3 10.4 3.4e-14 52.6 0.2 3.1 3 0 0 3 3 3 3 Conidiation protein 6 Arm-DNA-bind_3 PF13356.6 KIY71739.1 - 0.023 15.1 1.9 0.23 11.8 0.1 2.4 1 1 1 2 2 2 0 Arm DNA-binding domain SpoIIIAH PF12685.7 KIY71739.1 - 0.088 12.6 5.2 0.84 9.4 0.1 2.9 1 1 1 2 2 2 0 SpoIIIAH-like protein ATP-synt_DE PF00401.20 KIY71739.1 - 0.37 11.1 0.1 0.37 11.1 0.1 2.7 3 0 0 3 3 3 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain p450 PF00067.22 KIY71740.1 - 3.7e-58 197.4 0.0 1.5e-57 195.4 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 Y_phosphatase PF00102.27 KIY71741.1 - 7.4e-40 137.0 0.0 2.3e-39 135.4 0.0 1.8 1 1 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KIY71741.1 - 0.00018 21.6 0.0 0.0013 18.8 0.0 2.1 2 0 0 2 2 2 1 Inositol hexakisphosphate DSPc PF00782.20 KIY71741.1 - 0.034 14.0 0.0 0.22 11.3 0.0 2.0 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KIY71741.1 - 0.058 13.3 0.0 0.082 12.9 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family CRAL_TRIO PF00650.20 KIY71742.1 - 7.7e-22 77.7 0.0 1.5e-21 76.8 0.0 1.4 1 1 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KIY71742.1 - 0.012 15.8 0.0 0.042 14.0 0.0 1.9 2 0 0 2 2 2 0 CRAL/TRIO, N-terminal domain Homeobox_KN PF05920.11 KIY71744.1 - 1.5e-18 66.4 0.1 1.5e-18 66.4 0.1 4.1 4 0 0 4 4 4 1 Homeobox KN domain Homeodomain PF00046.29 KIY71744.1 - 1.8e-05 24.5 0.1 8.8e-05 22.3 0.0 2.1 2 0 0 2 2 2 1 Homeodomain LRR_4 PF12799.7 KIY71745.1 - 1.3e-20 73.1 6.5 3.7e-06 27.2 0.1 7.5 6 2 1 8 8 8 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KIY71745.1 - 5.4e-14 51.7 11.1 5.4e-07 29.3 0.3 6.1 6 1 1 7 7 7 3 Leucine rich repeat LRR_6 PF13516.6 KIY71745.1 - 6.2e-07 29.0 12.5 1.6 9.0 0.2 8.2 9 0 0 9 9 9 2 Leucine Rich repeat LRR_9 PF14580.6 KIY71745.1 - 0.0025 17.4 0.0 5.6 6.4 0.0 3.9 4 0 0 4 4 4 2 Leucine-rich repeat LRR_1 PF00560.33 KIY71745.1 - 0.005 17.2 16.8 32 5.6 0.1 8.8 8 2 0 8 8 8 1 Leucine Rich Repeat Aft1_HRA PF11786.8 KIY71747.1 - 7.4e-18 64.7 10.2 7.4e-18 64.7 10.2 2.1 2 0 0 2 2 2 1 Aft1 HRA domain bZIP_1 PF00170.21 KIY71747.1 - 6e-10 39.1 8.0 6e-10 39.1 8.0 1.6 2 0 0 2 2 1 1 bZIP transcription factor Aft1_OSA PF11785.8 KIY71747.1 - 4.2e-06 27.1 1.6 2.7e-05 24.5 1.6 2.4 1 0 0 1 1 1 1 Aft1 osmotic stress response (OSM) domain bZIP_2 PF07716.15 KIY71747.1 - 5.6e-06 26.3 7.5 5.6e-06 26.3 7.5 1.7 2 0 0 2 2 1 1 Basic region leucine zipper Myc_N PF01056.18 KIY71747.1 - 0.024 14.6 0.6 0.039 13.9 0.6 1.3 1 0 0 1 1 1 0 Myc amino-terminal region PBP1_TM PF14812.6 KIY71747.1 - 0.025 14.9 10.4 0.025 14.9 10.4 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal BNIP2 PF12496.8 KIY71747.1 - 0.025 15.0 2.2 0.045 14.2 2.2 1.4 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 DUF3246 PF11596.8 KIY71747.1 - 0.034 13.6 0.7 0.052 13.0 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) MCC-bdg_PDZ PF10506.9 KIY71747.1 - 0.058 13.4 0.3 0.1 12.6 0.3 1.4 1 0 0 1 1 1 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Pox_Ag35 PF03286.14 KIY71747.1 - 0.1 12.4 4.0 0.23 11.2 4.0 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Spt5_N PF11942.8 KIY71747.1 - 0.12 13.3 9.0 0.054 14.5 6.2 1.8 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Nop53 PF07767.11 KIY71747.1 - 1.9 7.8 13.2 4.8 6.5 13.2 1.6 1 1 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) ASD2 PF08687.11 KIY71747.1 - 6.4 6.2 9.2 15 5.0 9.2 1.6 1 1 0 1 1 1 0 Apx/Shroom domain ASD2 Isochorismatase PF00857.20 KIY71749.1 - 3.2e-23 82.8 0.1 1.4e-22 80.8 0.1 1.8 1 1 0 1 1 1 1 Isochorismatase family Sec63 PF02889.16 KIY71750.1 - 6.8e-21 74.6 0.0 1e-20 74.0 0.0 1.2 1 0 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.31 KIY71750.1 - 7.5e-14 51.6 0.2 1.8e-13 50.4 0.2 1.7 1 0 0 1 1 1 1 DnaJ domain DUF5638 PF18688.1 KIY71750.1 - 0.015 15.6 0.1 0.032 14.6 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5638) BTB PF00651.31 KIY71751.1 - 0.0036 17.5 0.0 0.0069 16.6 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain RRM_1 PF00076.22 KIY71752.1 - 5.6e-16 58.1 0.0 7.5e-16 57.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KIY71752.1 - 0.00025 20.7 0.0 0.00034 20.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L18 PF17135.4 KIY71753.1 - 1.1e-86 289.0 1.9 1.3e-86 288.8 1.9 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 KIY71753.1 - 0.0032 18.2 0.5 0.0032 18.2 0.5 2.1 2 1 0 2 2 2 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Tra_M PF05261.11 KIY71753.1 - 0.025 14.6 0.0 0.033 14.2 0.0 1.2 1 0 0 1 1 1 0 TraM protein, DNA-binding GN3L_Grn1 PF08701.11 KIY71754.1 - 4.6e-23 81.1 19.7 4.6e-23 81.1 19.7 2.3 2 0 0 2 2 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 KIY71754.1 - 1.3e-13 51.1 0.9 1e-10 41.7 0.0 2.9 2 1 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 KIY71754.1 - 1.8e-06 27.6 0.1 0.00015 21.3 0.0 2.6 2 1 0 2 2 2 1 Ferrous iron transport protein B AIG1 PF04548.16 KIY71754.1 - 3.7e-05 23.1 0.0 8.9e-05 21.9 0.0 1.7 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 KIY71754.1 - 8.5e-05 22.5 0.0 0.011 15.6 0.1 2.5 2 0 0 2 2 2 1 RsgA GTPase Septin PF00735.18 KIY71754.1 - 0.0012 18.2 0.0 0.0012 18.2 0.0 1.7 2 0 0 2 2 2 1 Septin GTP_EFTU PF00009.27 KIY71754.1 - 0.0035 16.9 0.7 4.7 6.7 0.2 3.8 2 2 0 2 2 2 2 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KIY71754.1 - 0.023 14.1 0.0 0.058 12.8 0.0 1.6 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit RTBV_P12 PF06361.11 KIY71754.1 - 0.026 14.9 0.0 0.07 13.5 0.0 1.7 1 0 0 1 1 1 0 Rice tungro bacilliform virus P12 protein Dynamin_N PF00350.23 KIY71754.1 - 0.04 14.0 0.4 0.04 14.0 0.4 4.6 3 2 1 4 4 4 0 Dynamin family AAA_16 PF13191.6 KIY71754.1 - 0.043 14.2 4.5 0.045 14.1 0.0 2.9 3 1 0 3 3 3 0 AAA ATPase domain Cwf_Cwc_15 PF04889.12 KIY71754.1 - 0.75 9.5 39.1 0.74 9.5 21.3 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Nop25 PF09805.9 KIY71754.1 - 1.9 9.0 29.3 0.67 10.4 7.0 2.5 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) F-box-like PF12937.7 KIY71755.1 - 3.1e-08 33.4 1.9 4.5e-08 32.9 0.4 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIY71755.1 - 0.00027 20.8 0.2 0.00082 19.2 0.2 1.9 1 1 0 1 1 1 1 F-box domain Adeno_E3_CR2 PF02439.15 KIY71756.1 - 0.049 13.4 0.1 0.085 12.6 0.1 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF2407_C PF13373.6 KIY71756.1 - 0.076 13.2 1.4 0.33 11.1 1.4 2.1 1 0 0 1 1 1 0 DUF2407 C-terminal domain Syndecan PF01034.20 KIY71756.1 - 0.17 11.8 0.2 0.31 11.0 0.2 1.4 1 0 0 1 1 1 0 Syndecan domain Inhibitor_I36 PF03995.13 KIY71756.1 - 0.17 11.8 2.5 1.4 8.9 0.0 2.9 2 0 0 2 2 2 0 Peptidase inhibitor family I36 SKG6 PF08693.10 KIY71756.1 - 1.3 8.5 3.1 4.2 6.9 3.1 1.9 1 0 0 1 1 1 0 Transmembrane alpha-helix domain MARVEL PF01284.23 KIY71757.1 - 7.1e-09 35.8 16.4 9.3e-09 35.5 16.0 1.4 1 1 0 1 1 1 1 Membrane-associating domain MBOAT PF03062.19 KIY71758.1 - 3.4e-42 145.0 4.0 3.4e-42 145.0 4.0 2.3 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family CPBP PF02517.16 KIY71758.1 - 0.47 10.9 0.1 0.47 10.9 0.1 2.7 2 0 0 2 2 2 0 CPBP intramembrane metalloprotease ATP-synt_J PF04911.12 KIY71758.1 - 4.8 6.8 5.3 6.3 6.5 0.3 2.8 3 0 0 3 3 3 0 ATP synthase j chain GDP_Man_Dehyd PF16363.5 KIY71759.1 - 2.4e-62 211.3 0.0 2.9e-62 211.0 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KIY71759.1 - 1.3e-47 162.3 0.0 1.6e-47 162.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KIY71759.1 - 2.8e-10 39.7 0.0 3.6e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KIY71759.1 - 1.9e-09 37.1 0.2 7.6e-05 22.0 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 KIY71759.1 - 4.8e-08 32.4 0.0 6.1e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KIY71759.1 - 3e-07 29.9 0.1 0.00084 18.6 0.0 2.9 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein adh_short PF00106.25 KIY71759.1 - 0.14 11.6 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Abhydrolase_1 PF00561.20 KIY71760.1 - 0.00041 20.1 0.0 0.086 12.5 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIY71760.1 - 0.0079 15.5 0.0 0.018 14.3 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 RGS PF00615.19 KIY71761.1 - 5.4e-41 139.6 0.0 1.3e-40 138.3 0.0 1.7 1 0 0 1 1 1 1 Regulator of G protein signaling domain DEP PF00610.21 KIY71761.1 - 3.1e-14 52.8 0.0 1e-07 31.9 0.0 3.5 3 0 0 3 3 3 3 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF2458 PF10454.9 KIY71762.1 - 4.4e-07 29.7 7.2 6.6e-07 29.1 7.2 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2458) DGCR6 PF07324.11 KIY71762.1 - 0.00021 21.0 7.6 0.00032 20.4 7.6 1.3 1 1 0 1 1 1 1 DiGeorge syndrome critical region 6 (DGCR6) protein IGR PF09597.10 KIY71762.1 - 0.093 12.9 0.6 0.33 11.1 0.1 2.0 2 0 0 2 2 2 0 IGR protein motif Cyt-b5 PF00173.28 KIY71763.1 - 2.1e-12 47.0 0.1 3.8e-12 46.2 0.1 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Bystin PF05291.11 KIY71764.1 - 9.9e-124 412.4 0.0 1.2e-123 412.0 0.0 1.1 1 0 0 1 1 1 1 Bystin Rsa3 PF14615.6 KIY71765.1 - 7.2e-16 57.5 0.1 9.6e-16 57.1 0.1 1.2 1 0 0 1 1 1 1 Ribosome-assembly protein 3 NST1 PF13945.6 KIY71765.1 - 0.39 10.8 5.7 7.9 6.5 5.7 2.1 1 1 0 1 1 1 0 Salt tolerance down-regulator SR-25 PF10500.9 KIY71765.1 - 0.5 10.0 23.7 0.63 9.6 7.4 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein SARAF PF06682.12 KIY71765.1 - 1.9 8.1 4.3 0.56 9.8 1.2 1.6 1 1 1 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis IMUP PF15761.5 KIY71765.1 - 2.4 8.9 31.5 1.9 9.2 8.9 2.5 1 1 1 2 2 2 0 Immortalisation up-regulated protein Adeno_terminal PF02459.15 KIY71765.1 - 2.8 6.2 5.3 0.15 10.4 0.2 1.4 2 0 0 2 2 2 0 Adenoviral DNA terminal protein TFIIF_alpha PF05793.12 KIY71765.1 - 4.2 5.8 14.3 5.6 5.4 14.3 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SRP-alpha_N PF04086.13 KIY71765.1 - 4.4 7.1 7.9 5.9 6.7 7.9 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Apt1 PF10351.9 KIY71765.1 - 4.8 5.9 8.3 5.4 5.8 8.3 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Cerato-platanin PF07249.12 KIY71766.1 - 3.5e-32 111.0 3.7 4.2e-32 110.8 3.7 1.1 1 0 0 1 1 1 1 Cerato-platanin ATP_bind_3 PF01171.20 KIY71767.1 - 8.1e-19 68.1 0.0 3e-18 66.2 0.0 1.8 1 1 1 2 2 2 1 PP-loop family zn-ribbon_14 PF16503.5 KIY71767.1 - 7.3e-15 54.2 2.4 7.3e-15 54.2 2.4 4.0 4 0 0 4 4 4 1 Zinc-ribbon DUF4428 PF14471.6 KIY71767.1 - 0.0094 15.9 1.5 0.0094 15.9 1.5 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4428) tRNA_Me_trans PF03054.16 KIY71767.1 - 0.022 13.6 0.0 0.033 13.0 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase RecR PF02132.15 KIY71767.1 - 0.028 14.0 1.1 0.028 14.0 1.1 2.6 3 0 0 3 3 3 0 RecR protein ThiI PF02568.14 KIY71767.1 - 0.061 12.9 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) Cerato-platanin PF07249.12 KIY71768.1 - 1.9e-33 115.1 0.9 2.3e-33 114.8 0.9 1.1 1 0 0 1 1 1 1 Cerato-platanin Nup160 PF11715.8 KIY71769.1 - 1.9e-22 79.6 0.0 3.2e-22 78.9 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 TPR_19 PF14559.6 KIY71769.1 - 0.041 14.4 0.3 0.66 10.5 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat PPR PF01535.20 KIY71769.1 - 0.12 12.7 0.1 0.58 10.5 0.1 2.3 1 0 0 1 1 1 0 PPR repeat TPR_6 PF13174.6 KIY71769.1 - 1.7 9.4 4.1 28 5.6 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Fungal_trans PF04082.18 KIY71772.1 - 2.1e-17 63.1 0.1 4.2e-17 62.0 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY71772.1 - 1.1e-05 25.5 9.1 1.9e-05 24.7 9.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_1 PF00515.28 KIY71773.1 - 4.2e-46 153.0 13.2 1.2e-05 24.9 0.3 8.5 8 0 0 8 8 8 8 Tetratricopeptide repeat TPR_2 PF07719.17 KIY71773.1 - 5.9e-34 113.4 21.1 5.5e-05 23.0 0.1 8.6 8 0 0 8 8 8 7 Tetratricopeptide repeat STI1 PF17830.1 KIY71773.1 - 5.4e-33 112.7 12.6 5.5e-16 58.2 6.9 2.9 2 0 0 2 2 2 2 STI1 domain TPR_16 PF13432.6 KIY71773.1 - 4.7e-25 88.0 15.5 6e-08 33.2 0.1 6.5 5 1 1 6 6 6 6 Tetratricopeptide repeat TPR_8 PF13181.6 KIY71773.1 - 4.1e-24 82.7 20.9 7.6e-05 22.6 0.1 8.8 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_11 PF13414.6 KIY71773.1 - 7.8e-23 79.9 12.5 5.3e-09 35.6 0.1 7.6 7 1 1 8 8 7 5 TPR repeat TPR_14 PF13428.6 KIY71773.1 - 3.5e-19 67.9 9.6 0.028 15.2 0.0 8.3 5 2 2 7 7 7 5 Tetratricopeptide repeat TPR_19 PF14559.6 KIY71773.1 - 3.8e-18 65.8 17.3 3.8e-07 30.5 0.3 7.2 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_12 PF13424.6 KIY71773.1 - 5e-18 65.2 13.3 1.1e-10 41.6 0.1 6.2 6 1 0 6 6 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 KIY71773.1 - 1e-17 62.8 9.1 0.0012 18.7 0.1 7.1 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.6 KIY71773.1 - 3.2e-13 49.1 1.8 0.006 16.9 0.1 6.9 6 1 0 6 6 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 KIY71773.1 - 5.1e-08 32.9 3.4 0.015 15.4 0.0 4.6 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.6 KIY71773.1 - 6.7e-08 32.2 8.1 0.1 12.5 0.0 7.0 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_6 PF13174.6 KIY71773.1 - 9.4e-08 32.2 14.9 1.1 10.1 0.0 7.7 7 0 0 7 7 7 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KIY71773.1 - 5.5e-05 23.3 8.0 0.17 12.1 0.1 5.2 4 1 2 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 XPC-binding PF09280.11 KIY71773.1 - 0.0075 16.0 8.2 0.25 11.1 0.3 2.6 2 0 0 2 2 2 2 XPC-binding domain TPR_4 PF07721.14 KIY71773.1 - 0.018 15.6 0.0 0.19 12.4 0.0 2.9 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF627 PF04781.12 KIY71773.1 - 0.029 14.4 5.6 0.54 10.3 0.6 4.1 3 1 0 4 4 4 0 Protein of unknown function (DUF627) GerD PF17898.1 KIY71773.1 - 0.033 14.1 5.7 0.82 9.6 3.9 3.3 2 1 0 2 2 2 0 Spore germination GerD central core domain TPR_3 PF07720.12 KIY71773.1 - 0.082 12.9 17.1 0.55 10.3 0.0 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 KIY71773.1 - 0.16 12.4 10.8 3.2 8.2 0.2 4.7 3 1 1 4 4 4 0 Alkyl sulfatase dimerisation PPR PF01535.20 KIY71773.1 - 0.17 12.2 0.0 7.2 7.1 0.0 3.3 2 0 0 2 2 2 0 PPR repeat MIT PF04212.18 KIY71773.1 - 0.22 11.6 21.6 3.7 7.7 0.0 7.0 7 0 0 7 7 7 0 MIT (microtubule interacting and transport) domain SPO22 PF08631.10 KIY71773.1 - 0.55 9.7 6.7 2.8 7.4 0.2 3.4 4 0 0 4 4 4 0 Meiosis protein SPO22/ZIP4 like Cyclin PF08613.11 KIY71774.1 - 6.1e-45 153.5 0.8 6.1e-45 153.5 0.8 1.9 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 KIY71774.1 - 0.081 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Cyclin, N-terminal domain ADH_N PF08240.12 KIY71775.1 - 0.0019 18.1 0.7 0.0061 16.4 0.1 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KIY71775.1 - 0.15 13.1 0.0 0.35 11.9 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase RRM_1 PF00076.22 KIY71776.1 - 3.5e-05 23.5 0.0 0.006 16.4 0.0 2.4 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LMBR1 PF04791.16 KIY71776.1 - 0.12 11.2 0.8 0.16 10.9 0.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein ARS2 PF04959.13 KIY71777.1 - 1.5e-15 58.1 0.7 1.5e-15 58.1 0.7 2.3 2 1 0 2 2 2 1 Arsenite-resistance protein 2 DUF3546 PF12066.8 KIY71777.1 - 4.3e-14 52.6 2.7 1.4e-13 51.0 0.2 3.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3546) DUF4187 PF13821.6 KIY71777.1 - 0.00039 20.2 1.2 0.00039 20.2 1.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4187) Response_reg PF00072.24 KIY71778.1 - 1.3e-22 80.0 0.1 5.6e-15 55.5 0.1 2.6 2 0 0 2 2 2 2 Response regulator receiver domain DUF4693 PF15764.5 KIY71781.1 - 0.004 16.8 0.1 0.0078 15.8 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4693) SH3_1 PF00018.28 KIY71782.1 - 8.3e-21 73.3 0.0 3.6e-11 42.5 0.0 2.9 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 KIY71782.1 - 1.2e-13 50.5 0.0 1.5e-06 27.7 0.0 3.3 3 0 0 3 3 3 2 Variant SH3 domain SH3_9 PF14604.6 KIY71782.1 - 2.6e-13 49.6 0.0 1.3e-05 24.9 0.0 2.8 2 0 0 2 2 2 2 Variant SH3 domain PB1 PF00564.24 KIY71782.1 - 1.5e-06 28.1 0.0 3e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 PB1 domain PX PF00787.24 KIY71782.1 - 0.00012 22.1 0.0 0.00027 20.9 0.0 1.6 1 0 0 1 1 1 1 PX domain Piwi PF02171.17 KIY71783.1 - 3e-84 282.8 0.0 4.2e-84 282.3 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 KIY71783.1 - 2.9e-18 66.8 0.0 5.8e-18 65.8 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 KIY71783.1 - 3.7e-15 55.3 0.1 4.2e-14 51.9 0.1 2.4 2 0 0 2 2 2 1 Argonaute linker 1 domain ArgoL2 PF16488.5 KIY71783.1 - 3.7e-07 30.4 0.0 1.1e-06 28.9 0.0 1.9 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoMid PF16487.5 KIY71783.1 - 1.3e-05 25.4 0.6 4.2e-05 23.7 0.6 1.9 1 0 0 1 1 1 1 Mid domain of argonaute Gyro_capsid PF04162.12 KIY71783.1 - 0.0046 15.5 0.2 0.0073 14.9 0.2 1.2 1 0 0 1 1 1 1 Gyrovirus capsid protein (VP1) NDUFA12 PF05071.16 KIY71784.1 - 6.4e-29 100.7 6.6 9.9e-29 100.0 6.6 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 MOZ_SAS PF01853.18 KIY71785.1 - 5.3e-62 208.7 0.3 9.1e-60 201.4 0.6 2.1 2 0 0 2 2 2 2 MOZ/SAS family zf-MYST PF17772.1 KIY71785.1 - 0.0016 18.0 8.3 0.022 14.4 8.3 2.8 1 1 0 1 1 1 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 KIY71785.1 - 0.038 14.4 0.0 0.076 13.5 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DNAPolymera_Pol PF11590.8 KIY71786.1 - 0.03 14.2 0.5 0.067 13.1 0.1 1.7 2 0 0 2 2 2 0 DNA polymerase catalytic subunit Pol DUF3445 PF11927.8 KIY71787.1 - 5.7e-57 192.9 0.0 6.9e-57 192.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) DUF45 PF01863.17 KIY71787.1 - 0.44 10.6 1.2 0.81 9.7 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF45 Ribosomal_L2_C PF03947.18 KIY71788.1 - 4.4e-46 156.2 2.6 7.4e-46 155.4 2.6 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 KIY71788.1 - 3e-15 55.9 0.1 7.1e-15 54.7 0.1 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain SSXT PF05030.12 KIY71790.1 - 3.1e-06 26.7 0.0 8.8e-06 25.3 0.0 1.7 1 0 0 1 1 1 1 SSXT protein (N-terminal region) JmjC PF02373.22 KIY71791.1 - 6.5e-14 52.3 0.0 1.4e-13 51.2 0.0 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 KIY71791.1 - 1.4e-05 25.0 0.0 7.1e-05 22.6 0.0 2.2 1 1 0 1 1 1 1 Cupin-like domain Cupin_2 PF07883.11 KIY71791.1 - 0.0074 16.0 0.0 0.025 14.3 0.0 1.8 2 0 0 2 2 2 1 Cupin domain Zf_RING PF16744.5 KIY71791.1 - 0.28 11.3 6.6 0.73 10.0 6.6 1.7 1 0 0 1 1 1 0 KIAA1045 RING finger Prok-RING_2 PF14445.6 KIY71791.1 - 4.3 7.6 9.5 14 6.0 9.5 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 p450 PF00067.22 KIY71792.1 - 4e-67 227.0 0.0 5e-67 226.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_S64 PF08192.11 KIY71795.1 - 0.068 11.7 0.1 0.31 9.5 0.0 1.8 2 0 0 2 2 2 0 Peptidase family S64 Fungal_trans PF04082.18 KIY71796.1 - 4.3e-35 121.0 0.0 9.4e-35 119.9 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY71796.1 - 1.7e-08 34.4 9.6 1.7e-08 34.4 9.6 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AdoMet_MTase PF07757.13 KIY71797.1 - 8.5e-37 125.9 0.0 1.4e-36 125.2 0.0 1.3 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_23 PF13489.6 KIY71797.1 - 0.0081 16.0 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 KIY71797.1 - 0.087 12.8 0.0 0.43 10.6 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.6 KIY71797.1 - 0.11 12.2 0.1 0.22 11.3 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase domain TMEM208_SND2 PF05620.11 KIY71798.1 - 6e-56 188.8 0.1 6.8e-56 188.6 0.1 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 Val_tRNA-synt_C PF10458.9 KIY71799.1 - 0.00063 20.0 12.5 0.67 10.3 0.0 3.9 2 1 1 3 3 3 3 Valyl tRNA synthetase tRNA binding arm GAGA_bind PF06217.12 KIY71799.1 - 0.31 11.3 13.1 0.42 10.9 13.1 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family V_ATPase_I PF01496.19 KIY71799.1 - 6.4 4.6 12.1 8.1 4.2 12.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family zf-MYND PF01753.18 KIY71800.1 - 1.5e-06 28.2 10.5 3.3e-06 27.1 10.5 1.6 1 0 0 1 1 1 1 MYND finger RNAse_A_bac PF18431.1 KIY71800.1 - 0.04 14.9 0.0 0.23 12.4 0.0 2.2 2 0 0 2 2 2 0 Bacterial CdiA-CT RNAse A domain DAP_B PF07930.12 KIY71800.1 - 0.05 13.6 0.0 0.092 12.7 0.0 1.4 1 0 0 1 1 1 0 D-aminopeptidase, domain B zf-Mss51 PF13824.6 KIY71800.1 - 1.3 9.1 4.3 4.1 7.6 4.3 1.8 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Zn_clus PF00172.18 KIY71803.1 - 0.003 17.6 10.1 0.19 11.9 10.2 2.3 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ATG16 PF08614.11 KIY71803.1 - 0.039 14.2 2.1 0.066 13.4 2.1 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Thymidylate_kin PF02223.17 KIY71805.1 - 1.3e-45 155.4 0.0 1.4e-45 155.2 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.6 KIY71805.1 - 0.00061 20.1 0.0 0.00086 19.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KIY71805.1 - 0.012 16.2 0.0 0.022 15.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain DUF463 PF04317.12 KIY71805.1 - 0.034 13.1 0.0 0.045 12.7 0.0 1.1 1 0 0 1 1 1 0 YcjX-like family, DUF463 AAA_14 PF13173.6 KIY71805.1 - 0.066 13.2 0.0 0.09 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain PRK PF00485.18 KIY71805.1 - 0.099 12.4 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family MobB PF03205.14 KIY71805.1 - 0.12 12.3 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DSPc PF00782.20 KIY71806.1 - 0.00021 21.1 0.0 0.00043 20.1 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 KIY71806.1 - 0.016 15.4 0.0 0.032 14.3 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate CDKN3 PF05706.12 KIY71806.1 - 0.029 14.0 0.0 0.05 13.3 0.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase3 PF13350.6 KIY71806.1 - 0.041 13.9 0.0 0.071 13.1 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Nucleoside_tran PF01733.18 KIY71807.1 - 1.4e-35 123.2 9.9 1.4e-35 123.2 9.9 2.2 1 1 0 1 1 1 1 Nucleoside transporter Pyr_redox_2 PF07992.14 KIY71809.1 - 5.3e-07 29.2 0.0 0.00074 18.8 0.0 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KIY71809.1 - 0.0015 18.5 0.0 0.0048 16.9 0.0 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 KIY71809.1 - 0.02 15.4 0.0 4.4 7.9 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIY71809.1 - 0.077 13.2 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain F-box-like PF12937.7 KIY71810.1 - 7.6e-07 28.9 8.7 9.7e-07 28.6 1.1 3.1 3 0 0 3 3 3 2 F-box-like F-box PF00646.33 KIY71810.1 - 0.38 10.7 3.0 8 6.5 1.4 3.5 2 1 0 2 2 2 0 F-box domain PKcGMP_CC PF16808.5 KIY71811.1 - 0.045 13.6 0.3 0.087 12.7 0.3 1.4 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF2838 PF10998.8 KIY71813.1 - 7e-42 142.2 8.4 1.5e-41 141.1 8.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2838) DUF3827 PF12877.7 KIY71813.1 - 0.32 9.3 0.8 0.46 8.8 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Adenylsucc_synt PF00709.21 KIY71814.1 - 4e-172 572.9 0.0 4.5e-172 572.7 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase Evr1_Alr PF04777.13 KIY71815.1 - 3.5e-27 94.8 0.1 5.2e-27 94.2 0.1 1.3 1 0 0 1 1 1 1 Erv1 / Alr family URO-D PF01208.17 KIY71816.1 - 3.6e-123 411.1 0.0 4.1e-123 410.9 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) SAM_2 PF07647.17 KIY71817.1 - 1.1e-07 31.9 0.0 3.3e-07 30.3 0.0 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KIY71817.1 - 0.00063 20.1 0.0 0.0013 19.1 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF1281 PF06924.11 KIY71817.1 - 0.04 13.4 0.0 0.071 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1281) DUF4508 PF14969.6 KIY71817.1 - 0.061 13.6 0.2 0.14 12.5 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4508) RRM_1 PF00076.22 KIY71820.1 - 8.7e-14 51.1 0.0 1.9e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PDH PF02153.17 KIY71821.1 - 1.4e-13 50.5 0.0 2e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.17 KIY71821.1 - 3.3e-05 24.4 0.0 9.3e-05 22.9 0.0 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 KIY71821.1 - 4.7e-05 23.1 0.0 0.00015 21.5 0.0 1.8 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA NAD_binding_2 PF03446.15 KIY71821.1 - 9.3e-05 22.6 0.0 0.0003 21.0 0.0 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 KIY71821.1 - 0.0031 17.6 0.0 0.0056 16.8 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 KIY71821.1 - 0.012 15.0 0.0 0.022 14.1 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 KIY71821.1 - 0.018 14.9 0.4 0.037 13.9 0.0 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.21 KIY71821.1 - 0.062 12.6 0.0 0.18 11.1 0.0 1.7 2 0 0 2 2 2 0 ThiF family TrkA_N PF02254.18 KIY71821.1 - 0.076 13.3 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox PF00070.27 KIY71821.1 - 0.11 13.0 0.0 0.25 11.9 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DIM1 PF02966.16 KIY71822.1 - 1.6e-67 225.3 0.1 1.8e-67 225.1 0.1 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 KIY71822.1 - 0.00019 21.4 0.1 0.00025 21.0 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KIY71822.1 - 0.019 15.3 0.5 0.029 14.7 0.4 1.3 1 1 0 1 1 1 0 Thioredoxin-like Tti2 PF10521.9 KIY71824.1 - 3.2e-44 151.6 0.3 4.8e-44 151.0 0.3 1.2 1 0 0 1 1 1 1 Tti2 family Aldo_ket_red PF00248.21 KIY71825.1 - 4.8e-42 144.1 0.0 6.4e-42 143.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family B12D PF06522.11 KIY71826.1 - 3.1e-11 42.9 0.1 4e-11 42.5 0.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit FAINT PF04385.15 KIY71826.1 - 0.06 13.4 0.1 0.076 13.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function, DUF529 WD40 PF00400.32 KIY71827.1 - 8.5e-09 35.9 19.7 0.00085 20.1 0.3 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat DUF2353 PF09789.9 KIY71828.1 - 1.1e-05 25.0 3.9 2.1e-05 24.1 3.9 1.4 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) HALZ PF02183.18 KIY71828.1 - 0.00019 21.6 5.1 0.0025 18.0 2.2 3.3 2 1 2 4 4 4 2 Homeobox associated leucine zipper ATG16 PF08614.11 KIY71828.1 - 0.0004 20.7 11.2 0.0004 20.7 11.2 2.7 2 1 0 2 2 1 1 Autophagy protein 16 (ATG16) Mto2_bdg PF12808.7 KIY71828.1 - 0.00047 20.4 13.8 0.008 16.5 1.1 3.3 3 0 0 3 3 3 2 Micro-tubular organiser Mto1 C-term Mto2-binding region Phage_GP20 PF06810.11 KIY71828.1 - 0.00047 20.0 3.4 0.14 12.0 2.3 2.5 1 1 1 2 2 2 2 Phage minor structural protein GP20 ZapB PF06005.12 KIY71828.1 - 0.00048 20.5 7.3 0.0032 17.9 1.2 2.6 2 0 0 2 2 2 1 Cell division protein ZapB Lebercilin PF15619.6 KIY71828.1 - 0.0017 18.1 5.7 0.18 11.5 1.1 2.3 1 1 1 2 2 2 2 Ciliary protein causing Leber congenital amaurosis disease bZIP_1 PF00170.21 KIY71828.1 - 0.0023 18.0 2.7 0.0074 16.4 0.4 2.6 2 1 0 2 2 2 1 bZIP transcription factor V_ATPase_I PF01496.19 KIY71828.1 - 0.0023 15.9 1.2 0.0034 15.4 1.2 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family IFT20 PF14931.6 KIY71828.1 - 0.0025 18.0 2.0 0.0047 17.1 2.0 1.5 1 0 0 1 1 1 1 Intraflagellar transport complex B, subunit 20 DivIC PF04977.15 KIY71828.1 - 0.0065 16.2 5.0 0.062 13.1 1.5 2.9 1 1 0 2 2 2 1 Septum formation initiator LPP PF04728.13 KIY71828.1 - 0.0074 16.7 5.7 0.053 13.9 1.1 3.4 2 2 2 4 4 4 1 Lipoprotein leucine-zipper CENP-F_leu_zip PF10473.9 KIY71828.1 - 0.0077 16.3 1.2 0.0077 16.3 1.2 2.9 2 1 1 3 3 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.12 KIY71828.1 - 0.011 15.8 3.7 0.43 10.6 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) CALCOCO1 PF07888.11 KIY71828.1 - 0.014 14.3 8.7 0.028 13.3 8.7 1.4 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like APG6_N PF17675.1 KIY71828.1 - 0.016 15.7 6.9 0.016 15.7 6.9 2.5 3 1 1 4 4 2 0 Apg6 coiled-coil region GAS PF13851.6 KIY71828.1 - 0.021 14.2 5.2 0.054 12.8 5.2 1.6 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding KASH_CCD PF14662.6 KIY71828.1 - 0.024 14.5 7.9 0.064 13.1 7.9 1.6 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH JIP_LZII PF16471.5 KIY71828.1 - 0.027 14.7 7.3 0.66 10.2 1.2 3.2 1 1 0 2 2 2 0 JNK-interacting protein leucine zipper II TMF_TATA_bd PF12325.8 KIY71828.1 - 0.037 14.2 9.4 1.3 9.3 2.4 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding YabA PF06156.13 KIY71828.1 - 0.038 14.6 4.0 0.079 13.6 0.9 2.5 1 1 1 2 2 2 0 Initiation control protein YabA ADIP PF11559.8 KIY71828.1 - 0.041 14.0 11.3 0.29 11.2 4.3 2.6 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Tektin PF03148.14 KIY71828.1 - 0.047 12.4 10.0 0.07 11.9 10.0 1.2 1 0 0 1 1 1 0 Tektin family Csm1_N PF18504.1 KIY71828.1 - 0.048 14.0 7.0 0.049 14.0 1.3 3.1 2 1 0 3 3 2 0 Csm1 N-terminal domain Spc7 PF08317.11 KIY71828.1 - 0.068 12.1 6.1 0.15 10.9 5.9 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein TACC_C PF05010.14 KIY71828.1 - 0.073 12.9 3.3 0.13 12.0 3.3 1.3 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal FAM76 PF16046.5 KIY71828.1 - 0.074 12.4 6.6 0.057 12.8 4.0 2.0 1 1 1 2 2 2 0 FAM76 protein CCDC92 PF14916.6 KIY71828.1 - 0.079 12.7 0.5 0.22 11.3 0.1 2.0 2 0 0 2 2 1 0 Coiled-coil domain of unknown function Shugoshin_N PF07558.11 KIY71828.1 - 0.097 12.6 0.0 0.4 10.6 0.0 2.1 2 0 0 2 2 1 0 Shugoshin N-terminal coiled-coil region BRE1 PF08647.11 KIY71828.1 - 0.098 12.7 2.6 0.19 11.8 2.2 1.7 1 1 0 1 1 1 0 BRE1 E3 ubiquitin ligase Scaffolding_pro PF11418.8 KIY71828.1 - 0.099 13.2 1.6 14 6.3 0.1 2.6 2 0 0 2 2 2 0 Phi29 scaffolding protein CASP_C PF08172.12 KIY71828.1 - 0.11 11.9 0.1 0.11 11.9 0.1 2.5 2 0 0 2 2 2 0 CASP C terminal SHE3 PF17078.5 KIY71828.1 - 0.12 12.1 9.6 0.54 9.9 2.1 2.3 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 Cnn_1N PF07989.11 KIY71828.1 - 0.12 12.6 4.6 14 5.9 3.7 3.0 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 MscS_porin PF12795.7 KIY71828.1 - 0.13 11.8 7.6 0.26 10.8 7.6 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain JAKMIP_CC3 PF16034.5 KIY71828.1 - 0.13 12.2 4.0 1.2 9.0 4.0 2.5 1 1 0 1 1 1 0 JAKMIP CC3 domain DUF3584 PF12128.8 KIY71828.1 - 0.14 9.6 10.8 0.18 9.3 10.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) PRKG1_interact PF15898.5 KIY71828.1 - 0.23 12.4 7.9 0.33 11.9 5.3 2.7 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain WHEP-TRS PF00458.20 KIY71828.1 - 0.29 11.3 1.3 18 5.6 0.0 2.5 2 0 0 2 2 2 0 WHEP-TRS domain UPF0449 PF15136.6 KIY71828.1 - 0.33 11.4 2.6 13 6.3 0.0 3.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 TSC22 PF01166.18 KIY71828.1 - 0.35 11.2 1.4 1.4 9.3 0.2 2.2 2 0 0 2 2 2 0 TSC-22/dip/bun family AAA_13 PF13166.6 KIY71828.1 - 0.44 9.1 4.0 0.64 8.6 4.0 1.1 1 0 0 1 1 1 0 AAA domain DUF3450 PF11932.8 KIY71828.1 - 0.61 9.3 9.2 0.96 8.7 8.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) Ax_dynein_light PF10211.9 KIY71828.1 - 0.83 9.6 6.3 7.1 6.5 0.8 2.3 1 1 1 2 2 2 0 Axonemal dynein light chain DUF4407 PF14362.6 KIY71828.1 - 1.2 8.4 8.1 0.11 11.8 2.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Filament PF00038.21 KIY71828.1 - 1.3 8.5 8.1 4.5 6.8 7.8 1.6 1 1 0 1 1 1 0 Intermediate filament protein TPR_MLP1_2 PF07926.12 KIY71828.1 - 1.5 8.9 13.2 0.67 10.0 3.0 2.7 2 1 0 3 3 2 0 TPR/MLP1/MLP2-like protein TMF_DNA_bd PF12329.8 KIY71828.1 - 1.8 8.6 5.6 4.2 7.4 1.2 2.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding SlyX PF04102.12 KIY71828.1 - 2.3 8.9 6.8 4.7 7.9 0.8 3.4 3 0 0 3 3 3 0 SlyX Seryl_tRNA_N PF02403.22 KIY71828.1 - 3.3 8.0 6.0 5.3 7.3 1.5 2.4 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain CorA PF01544.18 KIY71828.1 - 3.7 6.8 6.1 0.94 8.7 1.2 2.1 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Atg14 PF10186.9 KIY71828.1 - 4 6.4 13.3 0.84 8.7 6.0 2.8 2 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 TolA_bind_tri PF16331.5 KIY71828.1 - 4.7 7.4 9.2 1.1 9.4 1.3 2.7 1 1 1 2 2 2 0 TolA binding protein trimerisation Fez1 PF06818.15 KIY71828.1 - 5.2 7.5 9.6 11 6.4 8.3 2.0 1 1 1 2 2 2 0 Fez1 Cep57_CLD_2 PF14197.6 KIY71828.1 - 5.2 7.2 7.2 2.4 8.3 3.1 2.5 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 CENP-H PF05837.12 KIY71828.1 - 6.3 7.3 11.0 3.5 8.1 7.2 2.4 1 1 1 2 2 2 0 Centromere protein H (CENP-H) FlxA PF14282.6 KIY71828.1 - 9.5 6.3 9.5 0.17 11.9 1.3 2.4 2 1 0 2 2 1 0 FlxA-like protein Con-6 PF10346.9 KIY71829.1 - 1.4e-13 50.6 0.4 1.4e-13 50.6 0.4 1.6 2 0 0 2 2 2 1 Conidiation protein 6 MFS_1 PF07690.16 KIY71830.1 - 9.3e-21 74.1 30.3 9.3e-21 74.1 30.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily FBA PF04300.13 KIY71831.1 - 0.024 14.3 1.0 0.037 13.7 0.2 1.6 1 1 1 2 2 2 0 F-box associated region Lactamase_B PF00753.27 KIY71832.1 - 4.6e-11 43.1 3.7 7.4e-11 42.4 3.7 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KIY71832.1 - 2e-05 24.2 1.4 5.1e-05 22.9 1.3 1.7 2 0 0 2 2 2 1 Beta-lactamase superfamily domain DSPn PF14671.6 KIY71833.1 - 6e-40 137.0 0.0 9.3e-39 133.1 0.0 2.3 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 KIY71833.1 - 1.4e-14 54.1 0.0 2.4e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KIY71833.1 - 6.8e-05 22.5 0.0 0.00012 21.8 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KIY71833.1 - 0.02 15.0 0.0 0.038 14.1 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 KIY71833.1 - 0.11 12.5 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family A_deamin PF02137.18 KIY71834.1 - 6.8e-66 223.0 0.0 8e-66 222.7 0.0 1.0 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain MnmE_helical PF12631.7 KIY71835.1 - 1.8e-48 165.5 0.0 2.2e-48 165.2 0.0 1.1 1 0 0 1 1 1 1 MnmE helical domain TrmE_N PF10396.9 KIY71835.1 - 1.3e-36 125.4 0.0 2.4e-36 124.5 0.0 1.5 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.23 KIY71835.1 - 6.7e-17 61.6 0.0 1.5e-16 60.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KIY71835.1 - 0.00035 20.7 0.0 0.0014 18.7 0.0 1.8 1 1 1 2 2 2 1 Dynamin family FeoB_N PF02421.18 KIY71835.1 - 0.0081 15.7 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B EF-hand_1 PF00036.32 KIY71836.1 - 4.6e-27 91.5 13.2 3.3e-07 29.4 0.4 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KIY71836.1 - 8.1e-23 80.7 6.0 6.3e-13 49.0 1.6 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KIY71836.1 - 1.1e-20 71.7 8.1 4.5e-05 23.1 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KIY71836.1 - 2.4e-18 64.7 15.6 7.8e-06 25.2 0.5 4.5 4 1 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 KIY71836.1 - 8.5e-12 44.7 13.5 0.00019 21.2 1.4 4.4 2 1 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KIY71836.1 - 6.2e-06 26.5 0.0 0.019 15.3 0.1 2.4 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KIY71836.1 - 2.4e-05 24.2 6.1 0.0064 16.4 0.6 3.8 1 1 3 4 4 4 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 KIY71836.1 - 0.00097 19.4 0.1 0.42 11.0 0.1 2.9 2 1 1 3 3 3 1 EF-hand domain Dockerin_1 PF00404.18 KIY71836.1 - 0.091 13.0 3.2 2.1 8.6 2.5 3.0 2 1 0 2 2 2 0 Dockerin type I domain Homeodomain PF00046.29 KIY71836.1 - 0.16 11.8 0.2 0.42 10.5 0.0 1.8 2 0 0 2 2 2 0 Homeodomain Sld5 PF05916.11 KIY71837.1 - 0.0019 18.6 0.0 0.0025 18.2 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein Pkr1 PF08636.10 KIY71838.1 - 1.4e-19 70.0 3.8 1.7e-19 69.7 3.8 1.1 1 0 0 1 1 1 1 ER protein Pkr1 DUF4175 PF13779.6 KIY71838.1 - 0.12 10.3 0.4 0.13 10.1 0.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Abhydrolase_3 PF07859.13 KIY71839.1 - 2e-20 73.6 0.0 3.3e-20 72.9 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KIY71839.1 - 2.3e-13 49.7 0.0 3.4e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_6 PF12697.7 KIY71839.1 - 0.0041 17.8 0.2 0.0061 17.2 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family ERG2_Sigma1R PF04622.12 KIY71840.1 - 2.2e-93 311.4 0.0 2.5e-93 311.2 0.0 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein DUF5597 PF18120.1 KIY71840.1 - 0.088 12.9 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5597) F-box-like PF12937.7 KIY71841.1 - 1.1e-06 28.4 1.1 2.2e-06 27.4 1.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY71841.1 - 0.027 14.4 1.3 0.88 9.5 0.0 2.4 2 0 0 2 2 2 0 F-box domain SET PF00856.28 KIY71842.1 - 1.7e-14 54.6 0.0 2.5e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 SET domain HTH_21 PF13276.6 KIY71842.1 - 0.089 12.9 0.0 0.22 11.7 0.0 1.7 1 0 0 1 1 1 0 HTH-like domain C1_1 PF00130.22 KIY71842.1 - 6.4 6.7 10.6 0.1 12.5 3.3 1.8 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Ank_2 PF12796.7 KIY71844.1 - 1.7e-17 63.7 0.1 1.5e-08 35.1 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KIY71844.1 - 2.1e-17 63.3 1.4 3.7e-09 36.9 0.0 3.9 2 2 3 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 KIY71844.1 - 2.6e-14 52.9 1.0 1.2e-06 28.7 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 KIY71844.1 - 4.1e-12 45.1 0.1 0.00014 22.0 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 KIY71844.1 - 9.3e-12 44.9 0.3 0.00014 22.1 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeats (many copies) KilA-N PF04383.13 KIY71844.1 - 0.00012 21.9 0.4 0.0013 18.6 0.1 2.5 2 1 0 2 2 2 1 KilA-N domain KxDL PF10241.9 KIY71844.1 - 0.12 12.7 0.9 0.31 11.3 0.9 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein DUF724 PF05266.14 KIY71844.1 - 0.23 11.3 1.3 0.4 10.5 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) YabA PF06156.13 KIY71844.1 - 0.52 11.0 2.1 0.82 10.3 0.8 1.9 2 0 0 2 2 2 0 Initiation control protein YabA Methyltransf_13 PF08421.11 KIY71845.1 - 0.19 12.0 0.4 7.5 6.9 0.0 3.0 2 1 1 3 3 3 0 Putative zinc binding domain DUF3413 PF11893.8 KIY71846.1 - 0.21 10.7 0.0 0.24 10.5 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3413) Peptidase_M28 PF04389.17 KIY71847.1 - 1e-25 90.6 0.1 2.1e-25 89.6 0.1 1.6 1 0 0 1 1 1 1 Peptidase family M28 CDC27 PF09507.10 KIY71847.1 - 5.9e-25 88.5 95.3 2.2e-24 86.6 29.8 3.2 1 1 2 3 3 3 2 DNA polymerase subunit Cdc27 Peptidase_M20 PF01546.28 KIY71847.1 - 1.3e-07 31.6 0.1 2.4e-07 30.6 0.1 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Amino_oxidase PF01593.24 KIY71848.1 - 4.7e-64 217.3 0.0 5.4e-63 213.9 0.0 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KIY71848.1 - 9.5e-12 45.0 0.3 2.3e-11 43.7 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KIY71848.1 - 4.1e-05 23.0 0.1 6.8e-05 22.3 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KIY71848.1 - 7e-05 22.6 1.0 0.00083 19.0 0.3 2.4 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KIY71848.1 - 0.00071 19.0 0.2 0.001 18.6 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIY71848.1 - 0.0019 17.5 0.0 0.014 14.7 0.0 2.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIY71848.1 - 0.0038 17.8 0.1 0.15 12.7 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KIY71848.1 - 0.0087 15.4 0.1 0.034 13.4 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KIY71848.1 - 0.057 12.5 0.1 0.1 11.6 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain WD40 PF00400.32 KIY71849.1 - 1.1e-32 111.5 29.2 1e-06 29.4 0.4 8.4 8 0 0 8 8 8 6 WD domain, G-beta repeat F-box-like PF12937.7 KIY71849.1 - 2.6e-12 46.4 0.4 7.3e-12 45.0 0.4 1.8 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 KIY71849.1 - 7.5e-10 39.0 0.5 0.94 9.8 0.0 6.1 2 1 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KIY71849.1 - 6.4e-06 25.7 0.0 0.0034 16.8 0.0 2.8 3 0 0 3 3 3 2 WD40-like domain F-box PF00646.33 KIY71849.1 - 0.00019 21.2 0.2 0.00043 20.1 0.2 1.6 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.8 KIY71849.1 - 0.005 15.6 1.2 1.3 7.6 0.0 3.7 2 1 2 4 4 4 1 Nucleoporin Nup120/160 PQQ_2 PF13360.6 KIY71849.1 - 0.048 13.2 0.2 3.8 7.0 0.0 2.9 2 1 0 2 2 2 0 PQQ-like domain PQQ_3 PF13570.6 KIY71849.1 - 0.32 11.5 4.3 2 9.0 0.1 4.2 4 1 0 4 4 4 0 PQQ-like domain RCC1 PF00415.18 KIY71850.1 - 3.1e-17 62.9 8.6 7.4e-05 23.3 0.0 6.5 7 1 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KIY71850.1 - 1.8e-09 37.2 30.2 0.00019 21.1 1.2 6.7 7 0 0 7 7 7 3 Regulator of chromosome condensation (RCC1) repeat F-box-like PF12937.7 KIY71850.1 - 2.7e-05 23.9 0.1 6.2e-05 22.8 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY71850.1 - 0.064 13.1 0.1 0.17 11.8 0.1 1.8 1 1 0 1 1 1 0 F-box domain FOXP-CC PF16159.5 KIY71851.1 - 0.004 17.8 0.4 0.0064 17.1 0.4 1.4 1 0 0 1 1 1 1 FOXP coiled-coil domain zf-C2H2 PF00096.26 KIY71851.1 - 0.0071 16.7 0.4 0.015 15.8 0.4 1.6 1 0 0 1 1 1 1 Zinc finger, C2H2 type DUF2110 PF09883.9 KIY71851.1 - 0.11 12.1 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2110) Glyco_hydro_61 PF03443.14 KIY71852.1 - 0.0021 18.0 0.0 0.0025 17.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 M20_dimer PF07687.14 KIY71853.1 - 5.1e-10 39.2 0.0 1.3e-09 38.0 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 KIY71853.1 - 1.5e-08 34.6 0.4 2.5e-08 33.9 0.4 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 DnaJ-X PF14308.6 KIY71854.1 - 1.3e-62 211.0 1.1 1.3e-62 211.0 1.1 2.5 1 1 1 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.31 KIY71854.1 - 6.8e-25 87.0 3.1 2.4e-24 85.2 3.1 2.0 1 0 0 1 1 1 1 DnaJ domain Phage_sheath_1 PF04984.14 KIY71854.1 - 0.033 14.1 0.1 0.11 12.3 0.0 1.9 2 0 0 2 2 2 0 Phage tail sheath protein subtilisin-like domain Ndc1_Nup PF09531.10 KIY71854.1 - 0.26 9.9 5.6 0.35 9.5 5.6 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PET117 PF15786.5 KIY71854.1 - 0.32 11.3 7.2 0.32 11.3 2.9 2.9 2 0 0 2 2 2 0 PET assembly of cytochrome c oxidase, mitochondrial Nucleo_P87 PF07267.11 KIY71854.1 - 5.9 5.6 9.0 7.8 5.2 9.0 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 OmpH PF03938.14 KIY71854.1 - 6.9 7.0 13.2 5.7 7.3 6.5 3.3 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) Hamartin PF04388.12 KIY71854.1 - 8.9 4.8 9.3 13 4.3 9.3 1.2 1 0 0 1 1 1 0 Hamartin protein F-box-like PF12937.7 KIY71857.1 - 2.4e-07 30.6 0.3 5.6e-07 29.3 0.3 1.7 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KIY71857.1 - 0.041 14.3 0.3 57 4.3 0.0 4.4 2 1 1 4 4 4 0 Leucine Rich repeats (2 copies) FGGY_N PF00370.21 KIY71858.1 - 6.6e-24 84.8 0.0 4.3e-15 55.9 0.0 2.2 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 KIY71858.1 - 1.9e-16 60.4 0.0 5.8e-16 58.8 0.0 1.9 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain SUZ PF12752.7 KIY71859.1 - 1.6e-14 54.4 1.1 1.6e-14 54.4 1.1 4.1 3 1 0 3 3 3 1 SUZ domain R3H PF01424.22 KIY71859.1 - 0.0013 18.7 0.0 0.0035 17.3 0.0 1.7 1 0 0 1 1 1 1 R3H domain Aa_trans PF01490.18 KIY71860.1 - 3.2e-80 269.9 29.8 3.9e-80 269.6 29.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein IncE PF17627.2 KIY71860.1 - 1.3 9.0 0.0 1.3 9.0 0.0 3.8 5 0 0 5 5 5 0 Inclusion membrane protein E Peptidase_M28 PF04389.17 KIY71861.1 - 3.9e-28 98.5 0.0 2.8e-27 95.7 0.1 2.1 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M20 PF01546.28 KIY71861.1 - 8.2e-10 38.7 0.0 1.4e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Acetate_kinase PF00871.17 KIY71861.1 - 0.015 14.0 0.0 0.021 13.5 0.0 1.1 1 0 0 1 1 1 0 Acetokinase family DUF1712 PF08217.11 KIY71863.1 - 3.1e-20 72.2 0.0 4.3e-20 71.8 0.0 1.1 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1712) E1-E2_ATPase PF00122.20 KIY71864.1 - 1.2e-38 132.4 1.4 1.2e-38 132.4 1.4 2.6 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KIY71864.1 - 7.8e-35 120.2 6.5 7.8e-35 120.2 6.5 3.3 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KIY71864.1 - 6.1e-22 79.0 0.8 6.2e-10 39.7 0.4 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KIY71864.1 - 7e-14 51.7 0.0 1.3e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KIY71864.1 - 7.3e-10 38.4 0.0 1.8e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KIY71864.1 - 0.00011 22.1 0.4 0.00025 20.9 0.1 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2157 PF09925.9 KIY71864.1 - 0.017 14.9 6.8 1.1 9.1 0.2 3.4 4 0 0 4 4 4 0 Predicted membrane protein (DUF2157) HAD PF12710.7 KIY71864.1 - 0.034 14.6 0.0 0.63 10.4 0.0 2.4 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF3619 PF12279.8 KIY71864.1 - 0.42 11.0 2.3 1.8 8.9 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3619) DUF2231 PF09990.9 KIY71864.1 - 7.3 7.1 8.4 1.2 9.6 0.7 3.3 3 0 0 3 3 3 0 Predicted membrane protein (DUF2231) DUF202 PF02656.15 KIY71867.1 - 4.3e-05 23.9 0.8 0.00024 21.5 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) MARVEL PF01284.23 KIY71867.1 - 0.023 14.7 1.0 0.041 13.9 1.0 1.4 1 0 0 1 1 1 0 Membrane-associating domain SecG PF03840.14 KIY71867.1 - 0.076 13.1 0.5 0.076 13.1 0.5 2.2 2 0 0 2 2 2 0 Preprotein translocase SecG subunit SLATT_5 PF18160.1 KIY71867.1 - 0.14 11.4 0.1 0.14 11.4 0.1 1.6 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 DUF2970 PF11174.8 KIY71867.1 - 0.18 11.7 0.5 0.18 11.7 0.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2970) MTHFR PF02219.17 KIY71868.1 - 2e-102 342.4 0.0 2.8e-102 341.9 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase DUF87 PF01935.17 KIY71869.1 - 0.0029 17.8 0.0 2.3 8.2 0.0 2.5 2 0 0 2 2 2 2 Helicase HerA, central domain CpcD PF01383.21 KIY71869.1 - 0.0038 17.5 0.0 0.021 15.1 0.0 2.2 2 0 0 2 2 2 1 CpcD/allophycocyanin linker domain HATPase_c_3 PF13589.6 KIY71869.1 - 0.018 14.8 0.0 5.2 6.9 0.0 2.9 3 0 0 3 3 3 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase BTB PF00651.31 KIY71869.1 - 0.019 15.2 0.0 0.23 11.7 0.0 2.4 1 1 1 2 2 2 0 BTB/POZ domain RRN9 PF10680.9 KIY71869.1 - 0.73 10.2 4.5 4.9 7.5 2.1 2.9 2 1 0 2 2 2 0 RNA polymerase I specific transcription initiation factor LSM PF01423.22 KIY71870.1 - 1.6e-14 53.3 0.2 2.1e-14 52.9 0.2 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KIY71870.1 - 0.027 14.6 0.0 0.041 14.0 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain MCR_gamma PF02240.16 KIY71870.1 - 0.12 11.6 0.5 0.15 11.3 0.5 1.1 1 0 0 1 1 1 0 Methyl-coenzyme M reductase gamma subunit RPN6_N PF18055.1 KIY71871.1 - 1.5e-43 147.9 3.2 1.5e-43 147.9 3.2 2.4 3 0 0 3 3 3 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 KIY71871.1 - 2.1e-18 66.8 0.6 5.1e-18 65.5 0.1 2.0 2 0 0 2 2 2 1 PCI domain RPN6_C_helix PF18503.1 KIY71871.1 - 1.3e-11 44.0 1.2 3.2e-11 42.8 1.2 1.7 1 0 0 1 1 1 1 26S proteasome subunit RPN6 C-terminal helix domain TPR_7 PF13176.6 KIY71871.1 - 0.012 15.6 4.5 22 5.4 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_MalT PF17874.1 KIY71871.1 - 0.013 14.9 1.0 0.013 14.9 1.0 2.0 2 1 0 2 2 2 0 MalT-like TPR region IL3 PF02059.15 KIY71871.1 - 0.034 14.2 0.5 3.6 7.7 0.1 2.8 2 1 0 2 2 2 0 Interleukin-3 DDRGK PF09756.9 KIY71871.1 - 0.098 12.2 1.0 0.42 10.2 0.1 2.0 2 0 0 2 2 2 0 DDRGK domain TPR_12 PF13424.6 KIY71871.1 - 0.47 10.8 10.3 2.1 8.7 0.1 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat UIM PF02809.20 KIY71872.1 - 0.49 10.4 1.8 1.4 9.0 1.8 1.8 1 0 0 1 1 1 0 Ubiquitin interaction motif PIF1 PF05970.14 KIY71873.1 - 2e-58 198.3 0.1 3.1e-48 164.8 0.1 2.2 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 KIY71873.1 - 2.8e-22 79.4 0.0 4.5e-22 78.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KIY71873.1 - 8.6e-11 42.4 0.0 1.6e-10 41.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.14 KIY71873.1 - 1.7e-06 26.3 0.2 6.5e-05 21.1 0.0 2.1 2 0 0 2 2 2 1 Helicase UvrD_C_2 PF13538.6 KIY71873.1 - 0.00017 21.4 0.0 0.0004 20.1 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_7 PF12775.7 KIY71873.1 - 0.0015 18.0 0.1 0.0041 16.7 0.0 1.6 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_22 PF13401.6 KIY71873.1 - 0.0016 18.7 0.0 0.0079 16.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain SH3_13 PF18335.1 KIY71873.1 - 0.002 17.9 0.0 0.0048 16.7 0.0 1.6 1 0 0 1 1 1 1 ATP-dependent RecD-like DNA helicase SH3 domain Viral_helicase1 PF01443.18 KIY71873.1 - 0.0048 16.7 0.1 5.4 6.7 0.0 3.0 2 1 0 2 2 2 2 Viral (Superfamily 1) RNA helicase NACHT PF05729.12 KIY71873.1 - 0.014 15.3 0.0 0.026 14.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_5 PF07728.14 KIY71873.1 - 0.019 15.0 0.0 0.12 12.3 0.0 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KIY71873.1 - 0.026 14.9 0.0 0.056 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain TsaE PF02367.17 KIY71873.1 - 0.032 14.2 0.0 0.24 11.4 0.0 2.1 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF2075 PF09848.9 KIY71873.1 - 0.047 12.9 0.1 0.084 12.1 0.1 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 KIY71873.1 - 0.072 12.5 0.0 0.45 9.9 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein RNA_helicase PF00910.22 KIY71873.1 - 0.14 12.6 0.0 0.4 11.1 0.0 1.9 1 1 0 1 1 1 0 RNA helicase AAA PF00004.29 KIY71873.1 - 0.14 12.6 0.1 0.33 11.4 0.1 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DNA_pol_B_palm PF14792.6 KIY71874.1 - 5.7e-27 94.2 0.0 9.8e-27 93.4 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_lambd_f PF10391.9 KIY71874.1 - 9e-22 76.7 0.0 2.8e-20 71.9 0.1 2.8 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda DNA_pol_B_thumb PF14791.6 KIY71874.1 - 6.9e-19 67.8 0.0 1.3e-18 66.9 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta thumb HHH_8 PF14716.6 KIY71874.1 - 1.7e-15 57.1 0.0 7.1e-15 55.1 0.0 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH_5 PF14520.6 KIY71874.1 - 0.00021 21.8 0.0 0.012 16.2 0.0 2.5 1 1 1 2 2 2 2 Helix-hairpin-helix domain Cdd1 PF11731.8 KIY71874.1 - 0.0048 17.1 0.0 0.5 10.6 0.0 2.5 1 1 1 2 2 2 1 Pathogenicity locus HHH PF00633.23 KIY71874.1 - 0.094 12.6 0.1 0.33 10.9 0.0 2.0 2 0 0 2 2 2 0 Helix-hairpin-helix motif NTP_transf_2 PF01909.23 KIY71874.1 - 0.1 12.9 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 Nucleotidyltransferase domain LytR_C PF13399.6 KIY71874.1 - 0.15 13.0 0.0 0.43 11.6 0.0 1.8 1 0 0 1 1 1 0 LytR cell envelope-related transcriptional attenuator Methyltransf_11 PF08241.12 KIY71875.1 - 4.6e-12 46.4 0.0 8.2e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIY71875.1 - 4.6e-11 42.7 0.0 7.6e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIY71875.1 - 8.8e-11 42.4 0.0 1.8e-10 41.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIY71875.1 - 1.9e-07 31.1 0.0 2.9e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIY71875.1 - 8.9e-07 29.6 0.0 1.7e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 KIY71875.1 - 1.4e-05 25.1 0.0 0.00056 19.8 0.0 2.3 1 1 1 2 2 2 1 Hypothetical methyltransferase Ubie_methyltran PF01209.18 KIY71875.1 - 0.00011 21.6 0.0 0.00022 20.7 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_29 PF03141.16 KIY71875.1 - 0.0063 15.1 0.0 0.067 11.7 0.0 1.9 2 0 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_32 PF13679.6 KIY71875.1 - 0.0072 16.3 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 KIY71875.1 - 0.06 12.5 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family MTS PF05175.14 KIY71875.1 - 0.073 12.6 0.0 0.31 10.6 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase small domain CheR PF01739.18 KIY71875.1 - 0.12 11.8 0.0 0.82 9.1 0.0 2.0 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain Bac_rhamnosid6H PF17389.2 KIY71875.1 - 0.18 11.0 0.0 0.24 10.6 0.0 1.1 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain CNH PF00780.22 KIY71876.1 - 5.8e-72 242.6 0.0 8.6e-72 242.0 0.0 1.2 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 KIY71876.1 - 1.8e-31 109.8 0.0 2.9e-31 109.1 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.6 KIY71876.1 - 1.2e-30 106.4 0.0 2.6e-30 105.3 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain DEP PF00610.21 KIY71876.1 - 2.9e-12 46.5 0.0 5.7e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) UCH PF00443.29 KIY71877.1 - 9.4e-70 235.0 0.0 1.3e-69 234.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 KIY71877.1 - 1e-16 61.3 0.5 7.1e-16 58.6 0.0 2.6 3 0 0 3 3 3 1 DUSP domain UCH_1 PF13423.6 KIY71877.1 - 1.5e-13 51.0 0.0 8.6e-06 25.6 0.0 3.2 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 KIY71877.1 - 0.034 13.8 0.0 0.081 12.6 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-specific protease C-terminal PhnA_Zn_Ribbon PF08274.12 KIY71877.1 - 0.89 9.6 3.5 29 4.7 0.1 2.9 3 0 0 3 3 3 0 PhnA Zinc-Ribbon Abhydrolase_1 PF00561.20 KIY71878.1 - 6.6e-22 78.4 0.0 8.2e-20 71.5 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 KIY71878.1 - 5.8e-21 74.5 0.0 1e-20 73.7 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Hydrolase_4 PF12146.8 KIY71878.1 - 0.066 12.5 0.0 20 4.3 0.0 3.0 3 0 0 3 3 3 0 Serine aminopeptidase, S33 Glyco_hydro_16 PF00722.21 KIY71879.1 - 1.7e-05 24.4 0.0 4e-05 23.2 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 RRM_1 PF00076.22 KIY71880.1 - 2.5e-33 113.7 0.0 7.1e-18 64.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KIY71880.1 - 0.15 12.2 0.0 0.48 10.6 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif CNH PF00780.22 KIY71881.1 - 1.2e-43 149.7 0.0 5.2e-43 147.6 0.0 1.8 2 0 0 2 2 2 1 CNH domain Sugar_tr PF00083.24 KIY71882.1 - 1.2e-89 301.2 19.4 1.4e-89 301.1 19.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY71882.1 - 2.5e-27 95.7 14.1 2.5e-27 95.7 14.1 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_5 PF05631.14 KIY71882.1 - 5e-05 22.4 0.8 5e-05 22.4 0.8 2.6 2 1 1 3 3 3 2 Sugar-tranasporters, 12 TM TRI12 PF06609.13 KIY71882.1 - 0.0023 16.5 0.8 0.0033 15.9 0.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) BTB PF00651.31 KIY71883.1 - 1.6e-07 31.5 0.0 2.5e-06 27.7 0.0 2.8 2 1 1 3 3 3 1 BTB/POZ domain HATPase_c_3 PF13589.6 KIY71883.1 - 0.044 13.6 0.1 1.8 8.4 0.1 2.8 3 0 0 3 3 3 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PH_12 PF16457.5 KIY71885.1 - 5.3e-33 114.4 0.0 1.3e-32 113.1 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain ELMO_CED12 PF04727.13 KIY71885.1 - 4.4e-25 88.8 0.1 7.4e-25 88.1 0.1 1.3 1 0 0 1 1 1 1 ELMO/CED-12 family DUF3361 PF11841.8 KIY71885.1 - 5.5e-22 78.4 0.0 1.6e-21 76.8 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF3361) TUG-UBL1 PF11470.8 KIY71885.1 - 0.024 14.9 0.2 0.14 12.4 0.0 2.2 2 0 0 2 2 2 0 TUG ubiquitin-like domain Gcd10p PF04189.13 KIY71885.1 - 0.12 11.4 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Gcd10p family SKIP_SNW PF02731.15 KIY71886.1 - 2.3e-71 238.7 1.6 2.3e-71 238.7 1.6 2.5 2 0 0 2 2 2 1 SKIP/SNW domain SLAC1 PF03595.17 KIY71887.1 - 1.7e-54 185.3 46.5 2e-54 185.0 46.5 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel zf-CCCH PF00642.24 KIY71888.1 - 3.6e-09 36.3 19.6 3.8e-05 23.5 1.5 4.4 3 1 1 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) MAM33 PF02330.16 KIY71888.1 - 9.7e-05 22.4 1.4 0.00015 21.8 1.4 1.2 1 0 0 1 1 1 1 Mitochondrial glycoprotein zf_CCCH_4 PF18345.1 KIY71888.1 - 0.0047 16.9 24.7 2.7 8.2 0.8 5.8 5 1 0 5 5 5 3 Zinc finger domain CENP-B_dimeris PF09026.10 KIY71888.1 - 0.014 15.8 17.3 0.014 15.8 17.3 1.7 2 0 0 2 2 2 0 Centromere protein B dimerisation domain zf-CCCH_3 PF15663.5 KIY71888.1 - 0.023 14.9 12.8 0.027 14.7 1.4 3.3 1 1 2 3 3 3 0 Zinc-finger containing family SDA1 PF05285.12 KIY71888.1 - 0.077 12.4 3.0 0.1 12.0 3.0 1.2 1 0 0 1 1 1 0 SDA1 Torus PF16131.5 KIY71888.1 - 2.8 8.7 16.2 9.1 7.0 1.6 3.8 1 1 2 3 3 3 0 Torus domain CDC45 PF02724.14 KIY71888.1 - 3.5 5.8 7.3 4.9 5.3 7.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Defensin_beta PF00711.19 KIY71888.1 - 9 6.4 11.1 1.3 9.1 0.2 3.7 3 0 0 3 3 3 0 Beta defensin Acyltransferase PF01553.21 KIY71889.1 - 3.5e-19 68.8 0.0 5e-19 68.2 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase RNA_pol_Rpb4 PF03874.16 KIY71890.1 - 9.9e-18 64.6 0.1 1.1e-17 64.5 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 Copper-fist PF00649.18 KIY71892.1 - 1.4e-21 75.7 0.7 1.4e-21 75.7 0.7 2.4 2 0 0 2 2 2 1 Copper fist DNA binding domain Ribosomal_L32p PF01783.23 KIY71892.1 - 1.2 9.4 11.3 1 9.7 2.7 2.7 2 0 0 2 2 2 0 Ribosomal L32p protein family GCFC PF07842.12 KIY71893.1 - 3.5e-69 233.5 2.5 4.9e-69 233.0 2.5 1.2 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.23 KIY71893.1 - 2e-14 53.2 1.8 6.2e-14 51.6 1.8 1.9 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KIY71893.1 - 5.9e-08 32.7 1.6 2e-07 31.0 0.7 2.5 1 1 0 1 1 1 1 G-patch domain TIP_N PF12457.8 KIY71893.1 - 6.9e-08 32.8 14.6 6.9e-08 32.8 14.6 3.0 2 1 0 2 2 2 1 Tuftelin interacting protein N terminal Lamprin PF06403.11 KIY71893.1 - 0.078 12.9 5.7 0.18 11.8 5.7 1.5 1 0 0 1 1 1 0 Lamprin Pro-kuma_activ PF09286.11 KIY71894.1 - 6e-37 127.1 0.0 9.8e-37 126.4 0.0 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KIY71894.1 - 0.00076 18.8 2.0 0.0011 18.3 0.2 1.9 2 0 0 2 2 2 1 Subtilase family Neugrin PF06413.11 KIY71895.1 - 3.7e-14 53.3 0.4 4.9e-14 52.9 0.4 1.1 1 0 0 1 1 1 1 Neugrin MRP-L20 PF12824.7 KIY71895.1 - 9.6e-07 29.1 2.6 2.5e-06 27.7 2.6 1.9 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 MarR_2 PF12802.7 KIY71895.1 - 0.07 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 MarR family HTH_11 PF08279.12 KIY71895.1 - 0.084 12.8 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 HTH domain IATP PF04568.12 KIY71895.1 - 0.31 11.5 4.1 0.57 10.6 4.1 1.4 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP PseudoU_synth_1 PF01416.20 KIY71896.1 - 2.9e-15 56.7 0.0 8.3e-12 45.5 0.0 2.3 2 0 0 2 2 2 2 tRNA pseudouridine synthase Carb_kinase PF01256.17 KIY71897.1 - 6.8e-52 176.4 0.0 1.1e-51 175.7 0.0 1.3 1 1 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.12 KIY71897.1 - 0.018 14.4 0.0 0.028 13.8 0.0 1.2 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase Cation_ATPase_C PF00689.21 KIY71898.1 - 0.0016 18.2 0.5 0.0016 18.2 0.5 2.4 1 1 1 2 2 2 1 Cation transporting ATPase, C-terminus DUF2339 PF10101.9 KIY71898.1 - 0.002 16.8 8.7 0.0025 16.5 8.7 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2339) DUF979 PF06166.12 KIY71898.1 - 0.12 11.5 5.4 0.041 13.1 1.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF979) DUF2569 PF10754.9 KIY71898.1 - 0.13 12.7 11.8 3.5 8.1 6.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2569) MHYT PF03707.16 KIY71898.1 - 0.35 11.1 5.4 0.2 11.9 0.6 2.9 3 1 0 3 3 3 0 Bacterial signalling protein N terminal repeat Cyto_heme_lyase PF01265.17 KIY71899.1 - 3.1e-79 266.6 5.0 3.4e-77 259.9 5.0 2.1 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase LPD11 PF18824.1 KIY71899.1 - 0.21 11.7 0.3 0.55 10.3 0.2 1.7 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 11 UbiA PF01040.18 KIY71900.1 - 4e-44 150.8 24.2 5e-44 150.5 24.2 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Glyco_hydro_30 PF02055.16 KIY71901.1 - 3.1e-24 85.6 1.1 4.4e-24 85.1 1.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_59 PF02057.15 KIY71901.1 - 2.1e-14 53.4 0.3 3.2e-14 52.9 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydr_30_2 PF14587.6 KIY71901.1 - 3.9e-05 23.4 0.1 0.00012 21.8 0.1 1.8 1 1 0 1 1 1 1 O-Glycosyl hydrolase family 30 VPS28 PF03997.12 KIY71902.1 - 3.4e-68 229.0 0.0 4e-68 228.8 0.0 1.0 1 0 0 1 1 1 1 VPS28 protein Rep_3 PF01051.21 KIY71902.1 - 0.06 13.2 0.1 1.2 8.9 0.0 2.2 1 1 1 2 2 2 0 Initiator Replication protein F-box-like PF12937.7 KIY71903.1 - 3e-08 33.4 1.2 8e-08 32.1 1.2 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY71903.1 - 0.00055 19.7 2.1 0.0013 18.6 2.1 1.7 1 0 0 1 1 1 1 F-box domain F-box-like_2 PF13013.6 KIY71903.1 - 0.12 12.3 0.2 1 9.3 0.2 2.3 1 1 0 1 1 1 0 F-box-like domain Hydrophobin PF01185.18 KIY71904.1 - 3.5e-20 72.4 10.3 4.6e-20 72.0 10.3 1.2 1 0 0 1 1 1 1 Fungal hydrophobin Sec1 PF00995.23 KIY71905.1 - 3.9e-125 419.3 0.0 4.5e-125 419.1 0.0 1.0 1 0 0 1 1 1 1 Sec1 family PARP PF00644.20 KIY71906.1 - 9.7e-11 41.6 0.0 2.1e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain UQ_con PF00179.26 KIY71906.1 - 1.7e-07 30.9 0.0 4.4e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KIY71906.1 - 0.089 13.1 0.0 1.2 9.5 0.0 2.6 3 0 0 3 3 3 0 RWD domain Adaptin_N PF01602.20 KIY71907.1 - 3.9e-138 461.3 2.5 4.9e-138 461.0 2.5 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KIY71907.1 - 1.5e-59 200.6 0.9 8.9e-58 194.9 0.2 2.8 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KIY71907.1 - 1.7e-16 60.4 4.3 2.1e-06 28.0 0.0 6.2 2 2 3 6 6 6 3 HEAT repeats HEAT PF02985.22 KIY71907.1 - 9.4e-10 37.9 5.2 0.00014 21.8 0.1 6.0 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.6 KIY71907.1 - 3.3e-06 27.5 0.4 7.6 7.2 0.0 6.1 6 0 0 6 6 6 2 HEAT-like repeat RTP1_C1 PF10363.9 KIY71907.1 - 0.00086 19.5 1.3 0.76 10.0 0.0 4.3 2 2 1 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 KIY71907.1 - 0.0029 17.2 0.1 0.36 10.3 0.0 3.0 2 1 1 3 3 3 1 CLASP N terminal Arm PF00514.23 KIY71907.1 - 0.0043 17.0 6.5 9.6 6.4 0.0 6.1 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat Sec7_N PF12783.7 KIY71907.1 - 0.022 14.7 0.9 0.12 12.2 0.1 2.5 2 1 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Atg14 PF10186.9 KIY71909.1 - 0.21 10.6 7.4 0.32 10.0 7.4 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Fez1 PF06818.15 KIY71909.1 - 0.23 11.9 13.1 0.39 11.1 13.1 1.3 1 0 0 1 1 1 0 Fez1 Macoilin PF09726.9 KIY71909.1 - 0.23 10.0 11.4 0.33 9.5 11.4 1.1 1 0 0 1 1 1 0 Macoilin family VIT1 PF01988.19 KIY71909.1 - 2.1 8.1 5.3 4.8 7.0 5.3 1.6 1 0 0 1 1 1 0 VIT family Spc7 PF08317.11 KIY71909.1 - 2.9 6.7 13.2 5.1 5.9 13.2 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Carn_acyltransf PF00755.20 KIY71910.1 - 3.1e-179 597.4 0.0 3.5e-179 597.2 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase MFS_1 PF07690.16 KIY71911.1 - 3.4e-21 75.6 43.1 2.3e-14 53.1 23.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIY71911.1 - 1.5e-09 37.2 4.9 1.5e-09 37.2 4.9 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter PyrBI_leader PF08052.11 KIY71911.1 - 0.035 14.1 0.0 0.088 12.8 0.0 1.6 1 0 0 1 1 1 0 PyrBI operon leader peptide Polysacc_deac_1 PF01522.21 KIY71912.1 - 3.5e-30 104.5 0.0 7.6e-30 103.4 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide deacetylase RFX1_trans_act PF04589.13 KIY71912.1 - 0.14 12.3 0.3 0.14 12.3 0.3 2.5 2 0 0 2 2 2 0 RFX1 transcription activation region zf-C2H2_3 PF13878.6 KIY71915.1 - 0.22 11.4 1.1 0.38 10.6 1.1 1.4 1 0 0 1 1 1 0 zinc-finger of acetyl-transferase ESCO LRS4 PF10422.9 KIY71917.1 - 0.0015 18.2 1.0 0.0022 17.6 1.0 1.2 1 0 0 1 1 1 1 Monopolin complex subunit LRS4 Nucleo_P87 PF07267.11 KIY71917.1 - 0.34 9.7 4.3 0.46 9.3 4.3 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 SR-25 PF10500.9 KIY71917.1 - 6.6 6.3 11.2 71 2.9 11.2 2.0 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein AAA PF00004.29 KIY71919.1 - 5.1e-42 143.4 0.0 9.9e-42 142.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KIY71919.1 - 2.9e-12 46.2 0.1 5.7e-12 45.2 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 KIY71919.1 - 1.8e-10 40.6 0.6 3.5e-10 39.7 0.0 1.8 2 0 0 2 2 1 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 KIY71919.1 - 1.1e-07 32.4 0.0 8.5e-05 23.0 0.0 2.7 2 1 1 3 3 2 1 AAA ATPase domain AAA_5 PF07728.14 KIY71919.1 - 1.9e-07 31.2 0.1 2.9e-06 27.3 0.1 2.7 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KIY71919.1 - 3.5e-06 27.2 0.0 1.7e-05 25.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 KIY71919.1 - 8.7e-06 25.6 0.0 2e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KIY71919.1 - 0.00016 21.9 0.1 0.0063 16.8 0.0 2.4 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.13 KIY71919.1 - 0.0024 17.1 0.0 0.004 16.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Prot_ATP_OB_N PF17758.1 KIY71919.1 - 0.0031 17.1 0.1 0.012 15.2 0.0 2.0 2 0 0 2 2 2 1 Proteasomal ATPase OB N-terminal domain Mg_chelatase PF01078.21 KIY71919.1 - 0.0034 16.8 0.0 0.0067 15.8 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 KIY71919.1 - 0.0036 16.6 0.0 0.0062 15.8 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_18 PF13238.6 KIY71919.1 - 0.0042 17.6 0.1 0.013 16.0 0.0 1.9 2 1 0 2 2 1 1 AAA domain TsaE PF02367.17 KIY71919.1 - 0.0045 17.0 0.0 0.0079 16.2 0.0 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 KIY71919.1 - 0.0051 16.6 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.22 KIY71919.1 - 0.0056 17.0 0.0 0.011 16.1 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_33 PF13671.6 KIY71919.1 - 0.0058 16.8 0.0 0.013 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KIY71919.1 - 0.0061 16.1 0.0 0.012 15.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_14 PF13173.6 KIY71919.1 - 0.011 15.8 0.0 0.029 14.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 KIY71919.1 - 0.018 14.9 0.0 0.036 13.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 KIY71919.1 - 0.02 14.4 0.1 0.041 13.3 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein Sigma54_activat PF00158.26 KIY71919.1 - 0.02 14.6 0.0 0.058 13.1 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_28 PF13521.6 KIY71919.1 - 0.023 14.9 0.0 0.048 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KIY71919.1 - 0.023 14.4 0.0 0.045 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KIY71919.1 - 0.026 14.2 0.1 0.072 12.8 0.0 1.7 2 0 0 2 2 1 0 AAA domain ATPase PF06745.13 KIY71919.1 - 0.058 12.7 1.3 0.18 11.1 0.0 2.3 3 0 0 3 3 3 0 KaiC AAA_11 PF13086.6 KIY71919.1 - 0.059 13.2 1.3 0.3 10.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KIY71919.1 - 0.062 12.9 0.4 0.15 11.6 0.1 1.7 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 KIY71919.1 - 0.064 12.3 0.0 0.15 11.2 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NACHT PF05729.12 KIY71919.1 - 0.074 13.0 0.1 0.19 11.7 0.0 1.7 2 0 0 2 2 2 0 NACHT domain AAA_19 PF13245.6 KIY71919.1 - 0.12 12.7 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Mnd1 PF03962.15 KIY71919.1 - 0.19 12.1 0.3 0.54 10.6 0.3 1.7 1 0 0 1 1 1 0 Mnd1 HTH domain DUF4200 PF13863.6 KIY71919.1 - 2.9 8.3 6.7 0.18 12.2 1.2 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF4200) DRMBL PF07522.14 KIY71920.1 - 3.7e-31 107.6 0.0 6.2e-31 106.8 0.0 1.4 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 KIY71920.1 - 8.7e-08 31.9 0.0 1.5e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KIY71920.1 - 0.00017 21.7 0.1 0.00037 20.6 0.1 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Aminotran_3 PF00202.21 KIY71921.1 - 1.6e-77 260.9 0.1 2e-77 260.5 0.1 1.0 1 0 0 1 1 1 1 Aminotransferase class-III ZZ PF00569.17 KIY71922.1 - 3.5e-13 49.1 57.0 1.3e-06 28.1 2.5 6.0 6 0 0 6 6 6 4 Zinc finger, ZZ type PB1 PF00564.24 KIY71922.1 - 1.6e-08 34.3 1.1 2.6e-08 33.7 0.0 2.0 2 0 0 2 2 2 1 PB1 domain C1_2 PF03107.16 KIY71922.1 - 0.62 10.4 55.8 0.053 13.8 3.2 6.4 6 1 0 6 6 6 0 C1 domain PHF5 PF03660.14 KIY71923.1 - 2.4e-52 175.5 7.9 2.7e-52 175.3 7.9 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 KIY71923.1 - 0.035 12.0 4.6 0.039 11.8 4.6 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DZR PF12773.7 KIY71923.1 - 0.36 10.9 15.0 1.3 9.2 1.8 2.9 1 1 1 2 2 2 0 Double zinc ribbon C1_2 PF03107.16 KIY71923.1 - 1.5 9.2 17.1 0.29 11.5 2.2 2.6 1 1 1 2 2 2 0 C1 domain FA_hydroxylase PF04116.13 KIY71924.1 - 3.3e-22 79.3 24.4 3.3e-22 79.3 24.4 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily zf-CCHC_5 PF14787.6 KIY71925.1 - 0.0078 15.9 3.5 0.022 14.5 3.5 1.8 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.6 KIY71925.1 - 0.12 12.4 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 KIY71925.1 - 0.16 11.8 2.8 0.26 11.2 2.8 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 KIY71925.1 - 0.33 11.1 2.0 0.59 10.3 2.0 1.4 1 0 0 1 1 1 0 Zinc knuckle B277 PF17623.2 KIY71926.1 - 0.083 12.0 0.2 0.15 11.1 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function KRTAP PF11759.8 KIY71926.1 - 0.091 13.3 1.3 0.13 12.8 1.3 1.1 1 0 0 1 1 1 0 Keratin-associated matrix MRP-S26 PF14943.6 KIY71926.1 - 0.12 12.2 8.1 0.16 11.9 8.1 1.1 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 Cupin_8 PF13621.6 KIY71928.1 - 9.4 5.9 11.0 19 4.9 11.0 1.5 1 0 0 1 1 1 0 Cupin-like domain ADP_ribosyl_GH PF03747.14 KIY71930.1 - 2.9e-52 178.2 1.1 3.6e-52 177.9 1.1 1.0 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase FOXP-CC PF16159.5 KIY71931.1 - 0.0053 17.4 0.9 0.019 15.6 0.3 2.0 1 1 1 2 2 2 1 FOXP coiled-coil domain zf-C2H2_aberr PF17017.5 KIY71931.1 - 0.0068 16.6 0.0 0.0068 16.6 0.0 1.2 1 0 0 1 1 1 1 Aberrant zinc-finger zf-C2H2 PF00096.26 KIY71931.1 - 0.6 10.7 7.0 0.22 12.1 1.1 2.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIY71931.1 - 0.95 10.5 6.1 0.76 10.8 0.8 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger Glyco_transf_15 PF01793.16 KIY71932.1 - 3.4e-119 397.9 9.6 4.2e-119 397.6 9.6 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase EGF_3 PF12947.7 KIY71932.1 - 0.065 13.5 0.9 0.12 12.6 0.9 1.4 1 0 0 1 1 1 0 EGF domain Trimer_CC PF08954.11 KIY71933.1 - 0.0028 17.2 1.5 0.0073 15.8 1.5 1.7 1 0 0 1 1 1 1 Trimerisation motif DUF4808 PF16066.5 KIY71933.1 - 0.068 13.7 0.4 0.14 12.7 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4808) DUF2072 PF09845.9 KIY71933.1 - 0.13 12.5 1.2 0.22 11.8 1.2 1.3 1 0 0 1 1 1 0 Zn-ribbon containing protein Syntaxin PF00804.25 KIY71933.1 - 0.14 11.8 2.5 0.28 10.8 2.5 1.4 1 0 0 1 1 1 0 Syntaxin HAD_2 PF13419.6 KIY71934.1 - 1.3e-16 61.2 0.0 3.7e-11 43.4 0.0 2.1 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KIY71934.1 - 5.2e-13 49.8 0.0 1.2e-12 48.5 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KIY71934.1 - 0.00018 21.5 0.0 0.00042 20.3 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 KIY71934.1 - 0.031 14.7 0.0 0.75 10.2 0.0 2.4 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase adh_short PF00106.25 KIY71937.1 - 2.5e-29 102.1 0.0 3.7e-29 101.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIY71937.1 - 7.9e-24 84.5 0.1 1.1e-23 84.0 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIY71937.1 - 5.1e-08 33.0 0.0 8.5e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 KIY71937.1 - 0.0016 17.6 0.0 0.0023 17.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 KIY71937.1 - 0.046 13.2 0.0 0.16 11.4 0.0 1.9 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Sugar_tr PF00083.24 KIY71938.1 - 2.8e-119 399.0 27.0 3.2e-119 398.8 27.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY71938.1 - 1.2e-25 90.2 48.0 4.8e-22 78.4 19.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Lipase_3 PF01764.25 KIY71939.1 - 2.1e-25 89.2 0.0 2.8e-25 88.8 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KIY71939.1 - 0.00064 20.4 2.6 0.00065 20.4 1.2 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.13 KIY71939.1 - 0.0029 17.4 0.0 0.0041 16.9 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein DUF2974 PF11187.8 KIY71939.1 - 0.0063 16.1 0.0 0.025 14.1 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) UPF0227 PF05728.12 KIY71939.1 - 0.054 13.4 0.0 0.087 12.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) DUF676 PF05057.14 KIY71939.1 - 0.055 13.0 0.0 0.09 12.3 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 KIY71939.1 - 0.093 12.0 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 FMN_red PF03358.15 KIY71941.1 - 1.4e-08 34.7 0.0 1.9e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 KIY71941.1 - 1.7e-05 24.6 0.0 2.2e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold RVT_1 PF00078.27 KIY71942.1 - 1.2e-08 34.8 0.0 1.6e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Antimicrobial_9 PF08104.11 KIY71942.1 - 0.23 11.5 0.6 7.1 6.7 0.6 2.3 2 0 0 2 2 2 0 Ponericin L family DUF1664 PF07889.12 KIY71943.1 - 4.4e-05 23.5 0.7 6.5e-05 23.0 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) Golgin_A5 PF09787.9 KIY71943.1 - 0.0011 18.5 3.1 0.0013 18.3 3.1 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 5 APG6_N PF17675.1 KIY71943.1 - 0.0059 17.1 4.8 0.0083 16.6 4.8 1.3 1 0 0 1 1 1 1 Apg6 coiled-coil region HALZ PF02183.18 KIY71943.1 - 0.0085 16.3 4.8 0.1 12.8 0.1 2.7 3 0 0 3 3 3 1 Homeobox associated leucine zipper Spc7 PF08317.11 KIY71943.1 - 0.011 14.7 2.3 0.013 14.4 2.3 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Med4 PF10018.9 KIY71943.1 - 0.012 15.3 1.4 0.014 15.1 1.4 1.1 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 SPATA1_C PF15743.5 KIY71943.1 - 0.015 15.4 1.9 0.019 15.0 1.9 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated C-terminus YabA PF06156.13 KIY71943.1 - 0.023 15.3 2.3 0.057 14.1 2.3 1.6 1 1 0 1 1 1 0 Initiation control protein YabA Atg14 PF10186.9 KIY71943.1 - 0.03 13.4 0.2 0.033 13.3 0.2 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 KASH_CCD PF14662.6 KIY71943.1 - 0.032 14.1 6.1 0.05 13.4 4.4 1.8 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH Sec2p PF06428.11 KIY71943.1 - 0.037 14.0 2.0 0.058 13.4 1.6 1.5 1 1 0 1 1 1 0 GDP/GTP exchange factor Sec2p Halo_GVPC PF05465.13 KIY71943.1 - 0.069 13.4 8.8 0.21 11.9 1.6 2.3 2 0 0 2 2 2 0 Halobacterial gas vesicle protein C (GVPC) repeat DUF4407 PF14362.6 KIY71943.1 - 0.073 12.4 1.1 0.092 12.1 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TraF_2 PF13729.6 KIY71943.1 - 0.088 12.2 0.3 0.11 11.8 0.3 1.1 1 0 0 1 1 1 0 F plasmid transfer operon, TraF, protein EzrA PF06160.12 KIY71943.1 - 0.096 10.8 2.8 0.12 10.5 2.8 1.0 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA PI3K_P85_iSH2 PF16454.5 KIY71943.1 - 0.1 12.2 2.3 0.14 11.7 2.3 1.1 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Wbp11 PF09429.10 KIY71943.1 - 0.15 12.5 3.4 0.24 11.8 3.0 1.6 1 1 1 2 2 2 0 WW domain binding protein 11 Nitrate_red_del PF02613.15 KIY71943.1 - 0.22 11.6 2.4 0.28 11.2 2.4 1.2 1 0 0 1 1 1 0 Nitrate reductase delta subunit Prefoldin_2 PF01920.20 KIY71943.1 - 0.23 11.4 3.5 0.17 11.8 0.8 1.9 1 1 1 2 2 2 0 Prefoldin subunit GTP-bdg_M PF16360.5 KIY71943.1 - 0.35 11.5 4.5 2.4 8.8 1.1 2.6 1 1 1 2 2 2 0 GTP-binding GTPase Middle Region DivIC PF04977.15 KIY71943.1 - 0.45 10.3 5.1 1.3 8.8 4.8 1.9 1 1 0 1 1 1 0 Septum formation initiator FUSC PF04632.12 KIY71943.1 - 0.58 8.6 3.5 0.68 8.4 3.5 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family ZapB PF06005.12 KIY71943.1 - 0.64 10.5 7.1 1.4 9.4 7.0 1.7 1 1 0 1 1 1 0 Cell division protein ZapB Rootletin PF15035.6 KIY71943.1 - 0.85 9.6 6.9 0.62 10.0 2.1 1.9 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion DUF1003 PF06210.11 KIY71943.1 - 0.85 9.7 5.3 0.89 9.7 1.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1003) HalX PF08663.10 KIY71943.1 - 1.4 9.3 13.2 0.91 9.9 2.4 2.8 1 1 1 2 2 2 0 HalX domain DUF4140 PF13600.6 KIY71943.1 - 1.5 9.3 6.6 4.2 7.9 6.6 1.9 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF2205 PF10224.9 KIY71943.1 - 1.5 8.8 5.0 3.5 7.7 0.3 2.3 1 1 1 2 2 2 0 Short coiled-coil protein SlyX PF04102.12 KIY71943.1 - 2.5 8.8 6.1 9.3 6.9 2.3 2.2 1 1 1 2 2 2 0 SlyX KfrA_N PF11740.8 KIY71943.1 - 3.9 8.2 10.9 4.1e+02 1.7 10.9 2.3 1 1 0 1 1 1 0 Plasmid replication region DNA-binding N-term Rimk_N PF18030.1 KIY71946.1 - 0.12 12.7 0.0 0.19 12.1 0.0 1.3 1 0 0 1 1 1 0 RimK PreATP-grasp domain DUF2235 PF09994.9 KIY71947.1 - 4.5e-86 288.8 0.0 5.8e-86 288.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) BAAT_C PF08840.11 KIY71947.1 - 0.088 12.7 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Sugar_tr PF00083.24 KIY71948.1 - 3.3e-110 369.1 12.7 4.3e-110 368.7 12.7 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY71948.1 - 5.3e-31 107.8 43.5 1.6e-27 96.4 23.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KIY71948.1 - 3.8e-06 25.7 11.0 0.0046 15.6 4.2 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein His_Phos_2 PF00328.22 KIY71949.1 - 3.9e-46 158.1 0.0 4.7e-46 157.9 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) TRI5 PF06330.11 KIY71950.1 - 5.7e-15 55.1 0.0 7e-15 54.8 0.0 1.1 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) DUF5471 PF17565.2 KIY71953.1 - 2.7 8.3 5.5 6 7.2 5.5 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5471) Hamartin PF04388.12 KIY71953.1 - 8.7 4.9 14.6 11 4.6 14.6 1.0 1 0 0 1 1 1 0 Hamartin protein Oxidored-like PF09791.9 KIY71955.1 - 3.1e-20 71.6 0.4 5e-20 70.9 0.4 1.4 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal PRKG1_interact PF15898.5 KIY71955.1 - 0.09 13.7 3.4 3.8 8.5 0.1 2.2 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain Prefoldin PF02996.17 KIY71955.1 - 0.11 12.5 2.9 8.9 6.3 0.0 2.9 3 0 0 3 3 3 0 Prefoldin subunit DUF2235 PF09994.9 KIY71956.1 - 2.6e-80 269.8 0.0 3.4e-80 269.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) BAAT_C PF08840.11 KIY71956.1 - 0.011 15.7 0.0 0.017 15.0 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal BTB PF00651.31 KIY71957.1 - 0.046 13.9 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain Myb_DNA-binding PF00249.31 KIY71958.1 - 7.2e-36 122.1 5.1 8.3e-13 48.3 1.2 3.1 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KIY71958.1 - 3.7e-26 91.1 1.6 3.5e-11 43.2 0.0 3.1 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_2 PF08914.11 KIY71958.1 - 0.00025 21.2 0.1 0.72 10.1 0.0 2.8 3 0 0 3 3 3 2 Rap1 Myb domain Rap1_C PF11626.8 KIY71958.1 - 0.00058 19.9 0.6 0.25 11.4 0.1 3.0 1 1 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain SLIDE PF09111.10 KIY71958.1 - 0.0011 19.0 0.0 3.7 7.6 0.0 3.0 1 1 2 3 3 3 2 SLIDE Myb_DNA-bind_4 PF13837.6 KIY71958.1 - 0.015 15.7 8.1 0.31 11.4 2.5 3.3 3 1 0 3 3 3 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KIY71958.1 - 0.024 14.5 0.0 4.8 7.1 0.0 2.9 2 1 1 3 3 3 0 Myb DNA-binding like MADF_DNA_bdg PF10545.9 KIY71958.1 - 0.11 12.9 3.3 2.3 8.6 0.6 2.7 3 1 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like RNase_H PF00075.24 KIY71960.1 - 1.3e-22 80.5 0.0 2.3e-22 79.8 0.0 1.4 1 1 0 1 1 1 1 RNase H RVT_3 PF13456.6 KIY71960.1 - 0.071 12.9 0.0 0.86 9.4 0.0 2.2 1 1 0 1 1 1 0 Reverse transcriptase-like FMO-like PF00743.19 KIY71961.1 - 4.6e-14 51.7 0.1 3.7e-13 48.8 0.1 2.3 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KIY71961.1 - 7.5e-08 31.9 0.0 1.7e-07 30.7 0.0 1.5 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KIY71961.1 - 1.9e-06 27.4 0.0 2.8e-05 23.5 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KIY71961.1 - 4.5e-05 22.8 0.0 0.0013 18.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIY71961.1 - 0.0038 17.4 0.0 0.011 15.9 0.0 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.20 KIY71961.1 - 0.059 13.4 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase zf-MYND PF01753.18 KIY71962.1 - 3.9e-09 36.4 8.4 7.6e-09 35.5 8.4 1.5 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.16 KIY71962.1 - 0.11 12.4 4.3 0.27 11.2 4.3 1.7 1 0 0 1 1 1 0 HIT zinc finger DUF448 PF04296.13 KIY71962.1 - 0.31 10.9 2.2 1.6 8.6 1.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF448) SAMP PF05924.11 KIY71962.1 - 0.47 9.8 4.5 6.3 6.2 0.4 2.5 2 0 0 2 2 2 0 SAMP Motif zf-RING_6 PF14835.6 KIY71962.1 - 1.6 8.7 5.6 0.5 10.3 1.5 2.3 2 1 1 3 3 3 0 zf-RING of BARD1-type protein PHD PF00628.29 KIY71962.1 - 2.8 7.9 8.5 2.8 7.9 7.1 1.8 2 0 0 2 2 2 0 PHD-finger Myb_DNA-binding PF00249.31 KIY71964.1 - 3.5e-35 120.0 3.5 1.9e-11 43.9 0.1 3.2 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KIY71964.1 - 1.9e-24 85.6 0.1 3.9e-11 43.0 0.0 3.2 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KIY71964.1 - 0.003 17.4 0.0 4 7.4 0.0 2.5 2 0 0 2 2 2 2 Myb DNA-binding like Myb_DNA-bind_2 PF08914.11 KIY71964.1 - 0.0079 16.3 0.0 3.6 7.8 0.0 3.4 3 1 0 3 3 3 1 Rap1 Myb domain Rap1_C PF11626.8 KIY71964.1 - 0.059 13.5 0.0 4.6 7.4 0.0 2.8 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_4 PF13837.6 KIY71964.1 - 0.072 13.5 6.2 1.4 9.4 0.8 3.4 3 1 0 3 3 3 0 Myb/SANT-like DNA-binding domain SLIDE PF09111.10 KIY71964.1 - 0.15 12.1 0.0 9.1 6.3 0.0 2.4 1 1 0 2 2 2 0 SLIDE SANT_DAMP1_like PF16282.5 KIY71964.1 - 0.19 11.9 0.0 9.6 6.5 0.0 2.5 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 zf-C3HC4_3 PF13920.6 KIY71965.1 - 4.2e-05 23.3 16.2 4.2e-05 23.3 16.2 3.5 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIY71965.1 - 9.2e-05 22.7 14.3 9.2e-05 22.7 14.3 3.9 2 2 1 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 KIY71965.1 - 0.00064 19.5 14.9 0.00064 19.5 14.9 4.2 2 2 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C2H2_jaz PF12171.8 KIY71965.1 - 0.00071 19.8 0.4 0.00071 19.8 0.4 4.3 6 0 0 6 6 6 1 Zinc-finger double-stranded RNA-binding Prok-RING_4 PF14447.6 KIY71965.1 - 0.0011 18.8 12.5 0.0011 18.8 12.5 3.8 2 2 2 4 4 4 1 Prokaryotic RING finger family 4 zf-met PF12874.7 KIY71965.1 - 0.023 15.1 0.4 0.023 15.1 0.4 4.1 6 0 0 6 6 6 0 Zinc-finger of C2H2 type AKAP95 PF04988.12 KIY71965.1 - 1.7 8.8 6.6 2.3 8.4 0.8 2.3 1 1 1 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) Pkinase PF00069.25 KIY71966.1 - 3.9e-61 206.7 0.0 5.3e-61 206.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY71966.1 - 7.3e-33 113.9 0.0 4.9e-32 111.2 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Seadorna_VP7 PF07387.11 KIY71966.1 - 0.0019 17.3 0.1 0.0039 16.3 0.1 1.5 1 0 0 1 1 1 1 Seadornavirus VP7 Kinase-like PF14531.6 KIY71966.1 - 0.0021 17.4 0.0 0.004 16.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KIY71966.1 - 0.017 14.0 0.0 0.028 13.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 KIY71966.1 - 0.11 11.5 0.0 0.18 10.7 0.0 1.4 1 1 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 KIY71966.1 - 0.22 11.1 0.3 0.45 10.1 0.1 1.6 2 0 0 2 2 2 0 RIO1 family PAS_3 PF08447.12 KIY71967.1 - 2.4e-10 40.5 0.0 4.2e-09 36.6 0.0 2.2 2 0 0 2 2 2 1 PAS fold PAS PF00989.25 KIY71967.1 - 9.1e-07 28.9 0.0 9.2e-05 22.4 0.0 2.6 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 KIY71967.1 - 0.00039 20.6 0.0 1.4 9.2 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 KIY71967.1 - 0.0012 19.1 0.0 0.063 13.5 0.0 2.2 2 0 0 2 2 2 1 PAS domain PAS_11 PF14598.6 KIY71967.1 - 0.013 15.6 0.0 0.1 12.7 0.0 2.3 2 1 1 3 3 3 0 PAS domain Chorion_1 PF01723.16 KIY71967.1 - 0.034 14.1 0.2 0.069 13.1 0.2 1.5 1 0 0 1 1 1 0 Chorion protein GCD14 PF08704.10 KIY71968.1 - 4.4e-88 295.1 0.5 8.1e-87 291.0 0.5 2.0 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.6 KIY71968.1 - 6.4e-05 22.8 0.0 8.9e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KIY71968.1 - 0.00036 20.4 0.0 0.00071 19.4 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TAF4 PF05236.14 KIY71968.1 - 0.0026 17.6 0.9 0.0035 17.1 0.9 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family GCD14_N PF14801.6 KIY71968.1 - 0.0027 17.5 0.0 0.0094 15.8 0.0 1.9 2 0 0 2 2 2 1 tRNA methyltransferase complex GCD14 subunit N-term VGLL4 PF15245.6 KIY71968.1 - 0.0041 17.2 0.8 0.0059 16.7 0.8 1.2 1 0 0 1 1 1 1 Transcription cofactor vestigial-like protein 4 Fibrillarin PF01269.17 KIY71968.1 - 0.034 13.3 0.0 0.058 12.5 0.0 1.3 1 0 0 1 1 1 0 Fibrillarin Methyltransf_24 PF13578.6 KIY71968.1 - 0.06 14.4 1.5 0.061 14.3 0.1 1.8 2 1 0 2 2 2 0 Methyltransferase domain Ubie_methyltran PF01209.18 KIY71968.1 - 0.075 12.4 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family RR_TM4-6 PF06459.12 KIY71968.1 - 0.46 10.3 2.9 0.63 9.8 2.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 A_deaminase PF00962.22 KIY71969.1 - 5.6e-121 403.9 0.1 8.3e-121 403.3 0.1 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase MFS_1 PF07690.16 KIY71970.1 - 1.4e-23 83.5 67.9 2.7e-20 72.6 36.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KIY71970.1 - 0.0018 17.2 11.2 0.0018 17.2 11.2 1.9 1 1 1 2 2 2 1 MFS_1 like family OppC_N PF12911.7 KIY71970.1 - 6.1 6.9 7.2 0.5 10.4 0.5 2.9 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C AMP-binding PF00501.28 KIY71971.1 - 1.2e-72 244.8 0.0 1.6e-72 244.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KIY71971.1 - 3.7e-16 59.9 1.8 1.2e-14 55.1 0.1 2.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain p450 PF00067.22 KIY71972.1 - 1.5e-30 106.4 0.0 2e-30 105.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 YccJ PF13993.6 KIY71972.1 - 0.086 13.2 0.1 0.18 12.1 0.1 1.5 1 0 0 1 1 1 0 YccJ-like protein DUF4362 PF14275.6 KIY71972.1 - 0.14 12.4 0.0 0.3 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4362) Thioesterase PF00975.20 KIY71974.1 - 1.3e-07 32.0 0.0 2e-07 31.4 0.0 1.6 2 1 0 2 2 2 1 Thioesterase domain DUF3568 PF12092.8 KIY71975.1 - 0.68 10.0 4.5 0.14 12.3 0.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3568) FYRN PF05964.14 KIY71976.1 - 9e-19 67.1 0.7 1.5e-18 66.4 0.7 1.3 1 0 0 1 1 1 1 F/Y-rich N-terminus FYRC PF05965.14 KIY71976.1 - 4.7e-17 61.9 0.0 8.3e-17 61.1 0.0 1.3 1 0 0 1 1 1 1 F/Y rich C-terminus GMC_oxred_N PF00732.19 KIY71977.1 - 5.9e-60 203.1 0.0 8.8e-60 202.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIY71977.1 - 1e-30 107.1 0.0 1.9e-30 106.3 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KIY71977.1 - 4.5e-05 22.7 0.2 0.059 12.4 0.3 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KIY71977.1 - 0.00062 19.5 0.7 0.0029 17.2 0.7 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KIY71977.1 - 0.0043 17.3 0.8 0.012 15.8 0.8 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KIY71977.1 - 0.032 13.3 0.1 0.057 12.5 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.17 KIY71977.1 - 0.049 12.9 0.3 0.12 11.6 0.3 1.5 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.14 KIY71977.1 - 0.082 12.1 0.2 0.21 10.8 0.1 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KIY71977.1 - 0.13 11.5 0.3 13 4.9 0.3 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase F-box-like PF12937.7 KIY71980.1 - 4.5e-07 29.7 5.8 6.8e-07 29.1 4.6 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIY71980.1 - 0.2 11.6 2.0 2.5 8.1 0.4 2.9 2 0 0 2 2 2 0 F-box domain Avl9 PF09794.9 KIY71988.1 - 1.5e-124 415.5 0.0 1.8e-124 415.3 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 DUF2347 PF09804.9 KIY71988.1 - 1.4e-11 44.5 0.1 6.9e-05 22.6 0.0 3.1 3 0 0 3 3 3 2 Uncharacterized conserved protein (DUF2347) SPA PF08616.10 KIY71988.1 - 4.7e-10 39.4 0.1 0.0002 21.3 0.0 2.4 2 0 0 2 2 2 2 Stabilization of polarity axis zf-MYND PF01753.18 KIY71989.1 - 9.7e-08 32.0 10.6 3.7e-07 30.1 10.6 2.1 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 KIY71989.1 - 0.2 11.8 6.4 0.59 10.3 6.4 1.8 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 YjeF_N PF03853.15 KIY71990.1 - 1.3e-38 132.5 0.0 1.7e-38 132.2 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus PALP PF00291.25 KIY71990.1 - 0.043 13.2 0.0 0.059 12.8 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Lig_chan PF00060.26 KIY71991.1 - 0.74 9.6 4.1 1.5 8.6 4.1 1.5 1 0 0 1 1 1 0 Ligand-gated ion channel Helo_like_N PF17111.5 KIY71992.1 - 0.039 13.3 0.0 0.043 13.2 0.0 1.0 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins DivIC PF04977.15 KIY71992.1 - 0.33 10.7 3.4 0.47 10.3 3.4 1.3 1 0 0 1 1 1 0 Septum formation initiator zf-MYND PF01753.18 KIY71993.1 - 6.4e-09 35.8 14.0 1e-08 35.1 14.0 1.3 1 0 0 1 1 1 1 MYND finger zf-C3HC4_3 PF13920.6 KIY71993.1 - 0.1 12.5 10.8 0.17 11.8 10.8 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) OKR_DC_1_C PF03711.15 KIY71993.1 - 0.14 12.5 0.0 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, C-terminal domain zf-HIT PF04438.16 KIY71993.1 - 2 8.3 11.4 0.094 12.6 5.3 2.0 2 0 0 2 2 2 0 HIT zinc finger Aldo_ket_red PF00248.21 KIY71994.1 - 4.8e-42 144.1 0.2 8e-34 117.2 0.0 2.0 2 0 0 2 2 2 2 Aldo/keto reductase family zf-C2H2 PF00096.26 KIY71995.1 - 1.8e-10 40.7 8.6 8.4e-05 22.8 1.8 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KIY71995.1 - 3.4e-06 27.2 6.7 8.7e-06 25.9 1.6 4.4 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KIY71995.1 - 0.0063 17.3 7.0 0.049 14.5 1.1 4.0 4 0 0 4 4 4 2 C2H2-type zinc finger Methyltransf_25 PF13649.6 KIY71996.1 - 1.6e-17 64.0 0.0 3.6e-17 62.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIY71996.1 - 1.5e-13 51.2 0.0 4.1e-13 49.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIY71996.1 - 1.1e-08 35.0 0.0 2.4e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIY71996.1 - 4.1e-08 32.9 0.0 6.3e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KIY71996.1 - 9.6e-07 28.8 0.0 2e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIY71996.1 - 8.4e-06 26.5 0.0 1.6e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KIY71996.1 - 0.0034 16.7 0.0 0.0056 16.0 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_29 PF03141.16 KIY71996.1 - 0.0035 16.0 0.0 0.0061 15.2 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_4 PF02390.17 KIY71996.1 - 0.017 14.6 0.0 0.068 12.6 0.0 1.9 2 0 0 2 2 2 0 Putative methyltransferase FtsJ PF01728.19 KIY71996.1 - 0.044 13.9 0.0 0.083 13.0 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase ABM PF03992.16 KIY71997.1 - 0.00015 21.8 0.3 0.0068 16.5 0.1 2.4 3 0 0 3 3 3 2 Antibiotic biosynthesis monooxygenase SRF-TF PF00319.18 KIY71999.1 - 5.5e-21 73.8 0.1 8.1e-21 73.3 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) TSGP1 PF07771.11 KIY71999.1 - 6.2 7.0 9.1 3.3 7.9 0.8 2.3 2 0 0 2 2 2 0 Tick salivary peptide group 1 NicO PF03824.16 KIY72001.1 - 3e-50 171.1 6.8 4.5e-50 170.6 0.1 2.4 2 1 0 2 2 2 1 High-affinity nickel-transport protein DUF2207 PF09972.9 KIY72001.1 - 0.05 12.4 0.3 0.36 9.5 0.0 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Phage_holin_2_4 PF16082.5 KIY72001.1 - 0.54 10.0 8.4 0.5 10.1 4.8 2.6 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like MBOAT_2 PF13813.6 KIY72002.1 - 2.3e-12 47.0 2.2 2.3e-12 47.0 2.2 2.1 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family DUF727 PF05303.12 KIY72003.1 - 2e-05 24.6 0.9 0.00019 21.5 0.9 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF727) DUF2228 PF10228.9 KIY72003.1 - 0.11 12.2 0.0 0.14 11.9 0.0 1.0 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2228) DPBB_1 PF03330.18 KIY72004.1 - 0.021 15.1 0.1 0.036 14.3 0.1 1.4 1 0 0 1 1 1 0 Lytic transglycolase Barwin PF00967.17 KIY72004.1 - 0.1 12.4 3.7 0.26 11.2 3.7 1.7 1 1 0 1 1 1 0 Barwin family Linker_histone PF00538.19 KIY72006.1 - 1.3e-09 38.2 0.0 2e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 linker histone H1 and H5 family AhpC-TSA PF00578.21 KIY72007.1 - 6.6e-37 126.2 0.0 9.1e-37 125.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KIY72007.1 - 1.8e-14 53.7 0.0 2.4e-14 53.3 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 KIY72007.1 - 4.6e-12 45.6 0.0 7.8e-12 44.8 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin FKBP_C PF00254.28 KIY72008.1 - 1.7e-30 105.2 0.0 2e-30 105.0 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase OGFr_N PF04664.13 KIY72009.1 - 4.3e-59 199.5 0.6 5.6e-59 199.2 0.6 1.1 1 0 0 1 1 1 1 Opioid growth factor receptor (OGFr) conserved region Hexapep PF00132.24 KIY72010.1 - 1.1e-05 25.0 10.3 0.0078 15.9 0.2 3.6 2 2 2 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Lsr2 PF11774.8 KIY72010.1 - 0.17 12.0 0.0 0.25 11.5 0.0 1.2 1 0 0 1 1 1 0 Lsr2 Hexapep_2 PF14602.6 KIY72010.1 - 0.82 9.5 6.5 1 9.2 3.4 2.5 2 1 1 3 3 3 0 Hexapeptide repeat of succinyl-transferase DUF1848 PF08902.11 KIY72011.1 - 0.071 12.8 1.2 0.089 12.5 1.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1848) Adaptin_binding PF10199.9 KIY72012.1 - 2.3e-11 44.3 4.7 3.3e-10 40.6 4.0 2.7 2 1 0 2 2 2 1 Alpha and gamma adaptin binding protein p34 F-box-like PF12937.7 KIY72013.1 - 1.6e-08 34.3 0.6 4.3e-08 32.9 0.6 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY72013.1 - 5.6e-05 22.9 0.3 0.0084 16.0 0.0 3.3 3 0 0 3 3 3 1 F-box domain TPR_2 PF07719.17 KIY72013.1 - 0.005 16.8 0.0 6.8 7.1 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 KIY72013.1 - 0.01 15.7 0.2 4.6 7.2 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat CDC37_N PF03234.14 KIY72014.1 - 4.8e-41 140.7 1.0 4.8e-41 140.7 1.0 2.7 3 0 0 3 3 3 1 Cdc37 N terminal kinase binding CDC37_M PF08565.11 KIY72014.1 - 1.3e-31 109.0 0.1 3.4e-31 107.6 0.0 1.8 2 0 0 2 2 2 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 KIY72014.1 - 3.5e-17 62.4 0.5 3.5e-17 62.4 0.5 3.0 3 1 0 3 3 3 1 Cdc37 C terminal domain Rib_5-P_isom_A PF06026.14 KIY72015.1 - 6.9e-60 201.6 0.0 9e-60 201.2 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) FAD_binding_8 PF08022.12 KIY72016.1 - 0.023 14.8 0.0 0.045 13.8 0.0 1.4 1 0 0 1 1 1 0 FAD-binding domain Ferric_reduct PF01794.19 KIY72016.1 - 1.7 8.7 18.5 0.073 13.2 7.1 3.1 1 1 1 2 2 2 0 Ferric reductase like transmembrane component Ni_hydr_CYTB PF01292.20 KIY72016.1 - 3.1 7.3 17.0 1.7 8.2 6.7 2.8 1 1 1 2 2 2 0 Prokaryotic cytochrome b561 TctB PF07331.11 KIY72016.1 - 5 7.4 15.9 8.7 6.6 3.9 2.4 1 1 1 2 2 2 0 Tripartite tricarboxylate transporter TctB family DUF3379 PF11859.8 KIY72018.1 - 0.011 15.1 0.2 0.018 14.4 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3379) JAB PF01398.21 KIY72019.1 - 1.5e-30 105.6 0.0 3e-30 104.6 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 KIY72019.1 - 5e-27 94.5 0.9 8.8e-27 93.7 0.9 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Connexin PF00029.19 KIY72019.1 - 0.2 11.4 1.1 0.33 10.7 1.1 1.3 1 0 0 1 1 1 0 Connexin Prot_ATP_ID_OB PF16450.5 KIY72019.1 - 0.84 9.6 2.8 3.4 7.7 0.0 2.9 4 0 0 4 4 4 0 Proteasomal ATPase OB C-terminal domain DNA_binding_1 PF01035.20 KIY72020.1 - 9.8e-26 89.7 0.0 1.2e-25 89.5 0.0 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain DUF2367 PF10164.9 KIY72023.1 - 0.00011 22.7 10.4 0.00067 20.1 10.4 2.2 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2367) F-box-like PF12937.7 KIY72024.1 - 0.00075 19.3 0.2 0.0015 18.4 0.2 1.6 1 0 0 1 1 1 1 F-box-like CLTH PF10607.9 KIY72025.1 - 3e-14 53.1 0.1 3.8e-14 52.8 0.1 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 KIY72025.1 - 8.5e-05 22.4 0.0 0.00019 21.2 0.0 1.6 1 0 0 1 1 1 1 LisH F-box-like PF12937.7 KIY72026.1 - 8.5e-10 38.4 0.1 2.2e-09 37.1 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY72026.1 - 0.0049 16.7 1.1 0.045 13.6 0.1 2.7 2 0 0 2 2 2 1 F-box domain NAD_binding_8 PF13450.6 KIY72027.1 - 7.6e-11 42.1 0.1 1.9e-10 40.8 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.19 KIY72027.1 - 2.4e-10 39.5 0.1 1.2e-08 33.9 0.1 2.7 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KIY72027.1 - 0.00012 21.3 1.1 0.00027 20.2 0.0 2.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KIY72027.1 - 0.00023 20.6 0.1 0.0029 16.9 0.2 2.4 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KIY72027.1 - 0.00082 18.7 0.0 0.0098 15.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KIY72027.1 - 0.0022 17.2 0.0 0.0031 16.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KIY72027.1 - 0.0093 15.6 0.5 0.023 14.3 0.5 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase FGFR3_TM PF18123.1 KIY72027.1 - 0.021 14.3 2.6 0.11 12.1 0.1 2.8 3 0 0 3 3 3 0 Fibroblast growth factor receptor 3 transmembrane domain NAD_binding_9 PF13454.6 KIY72027.1 - 0.041 13.9 0.3 0.15 12.1 0.0 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding GIDA PF01134.22 KIY72027.1 - 0.47 9.5 0.8 0.79 8.7 0.8 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Peptidase_M36 PF02128.15 KIY72028.1 - 4.3e-161 536.2 1.2 5.7e-161 535.8 1.2 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.13 KIY72028.1 - 5.8e-11 42.0 0.3 1.2e-10 41.1 0.3 1.5 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif Pkinase PF00069.25 KIY72030.1 - 3.2e-25 89.0 0.0 3.9e-25 88.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY72030.1 - 3.3e-12 46.2 0.0 4.4e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIY72030.1 - 1.6e-07 30.5 0.0 2.1e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KIY72030.1 - 0.011 15.7 0.0 2.1 8.2 0.0 2.3 1 1 0 2 2 2 0 Phosphotransferase enzyme family Ish1 PF10281.9 KIY72031.1 - 3.5e-63 209.6 30.1 9.7e-11 41.8 0.3 7.8 7 0 0 7 7 7 7 Putative stress-responsive nuclear envelope protein SLATT_4 PF18186.1 KIY72031.1 - 2.5e-06 27.2 1.9 1.3 8.6 0.1 5.3 5 0 0 5 5 5 2 SMODS and SLOG-associating 2TM effector domain family 4 SAP PF02037.27 KIY72031.1 - 0.0065 16.2 0.0 49 3.8 0.0 4.3 4 0 0 4 4 4 0 SAP domain HTH_32 PF13565.6 KIY72031.1 - 0.016 15.8 0.5 22 5.7 0.1 4.7 3 2 1 5 5 5 0 Homeodomain-like domain HeH PF12949.7 KIY72031.1 - 0.1 12.4 0.5 1.1e+02 2.6 0.0 4.3 4 0 0 4 4 4 0 HeH/LEM domain DUF4125 PF13526.6 KIY72031.1 - 0.37 10.4 4.7 1.7 8.2 0.1 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF4125) Slx4 PF09494.10 KIY72031.1 - 3.2 7.8 5.1 64 3.6 0.0 4.5 6 0 0 6 6 6 0 Slx4 endonuclease Iron_traffic PF04362.14 KIY72031.1 - 7 6.4 8.7 0.16 11.7 0.3 2.8 4 0 0 4 4 4 0 Bacterial Fe(2+) trafficking SNF2_N PF00176.23 KIY72032.1 - 1.2e-58 198.5 0.0 2.1e-58 197.8 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.10 KIY72032.1 - 1.1e-41 143.1 8.0 1.9e-41 142.2 8.0 1.4 1 0 0 1 1 1 1 Rad54 N terminal Helicase_C PF00271.31 KIY72032.1 - 1.2e-16 61.0 0.0 3.6e-16 59.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIY72032.1 - 6.1e-08 32.9 0.0 1.7e-07 31.4 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KIY72032.1 - 8.7e-07 28.4 1.3 1e-05 24.9 0.0 3.0 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 AAA_22 PF13401.6 KIY72032.1 - 0.0058 16.9 0.1 0.37 11.1 0.0 3.2 2 1 0 2 2 2 1 AAA domain NEXCaM_BD PF16644.5 KIY72032.1 - 0.12 12.7 0.1 0.31 11.3 0.1 1.7 1 0 0 1 1 1 0 Regulatory region of Na+/H+ exchanger NHE binds to calmodulin Tfb2 PF03849.14 KIY72033.1 - 2e-119 398.8 0.0 2.8e-119 398.2 0.0 1.2 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 KIY72033.1 - 5.6e-27 94.0 0.4 1e-26 93.1 0.4 1.5 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 KIY72033.1 - 0.0007 19.7 0.0 0.0014 18.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain EF-hand_7 PF13499.6 KIY72034.1 - 1.6e-25 89.3 13.2 9.1e-15 54.9 3.6 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KIY72034.1 - 2.1e-24 83.2 14.6 5e-09 35.1 0.2 4.2 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 KIY72034.1 - 7.7e-21 72.2 10.0 5.6e-08 32.1 0.1 4.4 3 1 1 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 KIY72034.1 - 1.2e-16 60.3 9.9 7.4e-11 41.7 0.8 3.4 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 KIY72034.1 - 1.6e-15 55.8 5.2 1.9e-05 23.9 0.6 3.6 3 0 0 3 3 3 3 EF hand EF-hand_9 PF14658.6 KIY72034.1 - 4.9e-14 52.4 1.2 9.4e-06 25.9 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 KIY72034.1 - 8.5e-08 32.1 4.4 0.00042 20.2 0.1 2.6 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 KIY72034.1 - 0.00029 20.8 1.7 0.051 13.5 0.0 3.2 2 1 0 3 3 3 1 Caleosin related protein Dockerin_1 PF00404.18 KIY72034.1 - 0.027 14.7 0.2 1.1 9.5 0.2 2.3 2 0 0 2 2 2 0 Dockerin type I domain SPARC_Ca_bdg PF10591.9 KIY72034.1 - 0.03 14.7 2.6 0.61 10.4 0.3 2.3 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_14 PF17959.1 KIY72034.1 - 0.18 12.2 1.5 13 6.3 0.1 2.6 2 1 0 2 2 2 0 EF-hand domain Torus PF16131.5 KIY72035.1 - 2e-08 34.9 0.0 3.5e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Torus domain zf_CCCH_4 PF18345.1 KIY72035.1 - 2.2e-05 24.4 2.7 2.2e-05 24.4 2.7 2.2 2 0 0 2 2 2 1 Zinc finger domain zf-CCCH PF00642.24 KIY72035.1 - 0.0004 20.2 1.7 0.0012 18.7 1.7 1.8 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 KIY72035.1 - 0.00083 19.6 0.3 0.0089 16.2 0.1 2.3 2 0 0 2 2 2 1 Zinc-finger containing family RRM_1 PF00076.22 KIY72035.1 - 0.0039 17.0 0.0 0.0078 16.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_2 PF14608.6 KIY72035.1 - 0.016 15.7 2.1 0.048 14.1 2.1 1.9 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 KIY72035.1 - 0.06 13.2 2.2 0.16 11.8 2.2 1.8 1 0 0 1 1 1 0 CCCH-type zinc finger RRM_occluded PF16842.5 KIY72035.1 - 0.081 12.8 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif DUF2039 PF10217.9 KIY72035.1 - 9.3 6.7 9.7 1.2 9.5 2.8 2.5 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) NAD_binding_7 PF13241.6 KIY72036.1 - 3.8e-27 94.8 0.0 6.4e-27 94.0 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 KIY72036.1 - 6.7e-20 70.5 0.2 1.5e-19 69.4 0.2 1.6 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 KIY72036.1 - 1e-11 44.0 0.1 2.3e-11 42.9 0.1 1.6 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central ThiF PF00899.21 KIY72036.1 - 0.075 12.4 0.2 0.78 9.0 0.0 2.4 3 0 0 3 3 3 0 ThiF family TrkA_N PF02254.18 KIY72036.1 - 0.19 12.0 0.0 0.34 11.2 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Phos_pyr_kin PF08543.12 KIY72037.1 - 6.1e-12 45.5 0.0 1.2e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 KIY72037.1 - 0.00032 20.1 0.0 0.00067 19.0 0.0 1.6 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Actin PF00022.19 KIY72038.1 - 5.1e-113 377.8 0.0 2.3e-112 375.6 0.0 1.7 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KIY72038.1 - 8.6e-05 21.5 0.0 0.00014 20.8 0.0 1.2 1 0 0 1 1 1 1 MreB/Mbl protein Carn_acyltransf PF00755.20 KIY72039.1 - 1.5e-202 674.4 0.0 1.7e-202 674.2 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase RTC PF01137.21 KIY72040.1 - 1e-58 198.2 0.0 1.2e-58 198.0 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 KIY72040.1 - 3.1e-39 133.6 0.0 5e-39 133.0 0.0 1.3 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain Hydrolase_6 PF13344.6 KIY72041.1 - 2e-30 104.9 0.0 3.1e-30 104.3 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KIY72041.1 - 1.6e-18 66.5 0.0 3.3e-18 65.5 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 KIY72041.1 - 4.7e-12 46.7 0.0 6e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KIY72041.1 - 6e-10 39.5 0.0 0.0014 18.8 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 KIY72041.1 - 0.016 14.8 0.1 0.042 13.5 0.0 1.7 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase Ribosomal_L7Ae PF01248.26 KIY72041.1 - 0.018 14.8 0.0 0.033 13.9 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PIG-F PF06699.11 KIY72042.1 - 3.6e-32 112.0 5.0 7e-32 111.0 3.8 1.8 1 1 1 2 2 2 1 GPI biosynthesis protein family Pig-F HlyIII PF03006.20 KIY72042.1 - 0.0032 17.2 0.9 0.026 14.2 0.7 2.1 1 1 1 2 2 2 1 Haemolysin-III related UPF0016 PF01169.19 KIY72042.1 - 1.4 9.3 7.0 3.6 8.0 1.2 3.2 3 0 0 3 3 3 0 Uncharacterized protein family UPF0016 VRR_NUC PF08774.11 KIY72043.1 - 6.2e-23 80.9 0.1 5.5e-22 77.9 0.0 2.4 2 0 0 2 2 2 1 VRR-NUC domain zf-RING_2 PF13639.6 KIY72044.1 - 7.7e-10 39.0 4.2 1.5e-09 38.0 4.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KIY72044.1 - 1.3e-09 37.9 2.0 2.6e-09 36.9 2.0 1.5 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KIY72044.1 - 2.1e-08 34.0 3.0 5.9e-08 32.6 1.1 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KIY72044.1 - 1.2e-07 31.5 5.1 4.3e-07 29.7 5.1 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIY72044.1 - 1.7e-07 31.0 1.4 1.3e-06 28.1 2.0 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KIY72044.1 - 1.4e-06 28.0 5.8 3.2e-06 26.9 1.0 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KIY72044.1 - 3.1e-05 23.7 8.7 0.00054 19.8 8.5 2.6 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 Rtf2 PF04641.12 KIY72044.1 - 0.0001 21.8 0.1 0.00013 21.4 0.1 1.4 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_4 PF14570.6 KIY72044.1 - 0.00024 20.8 5.4 0.00067 19.4 5.4 1.8 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 KIY72044.1 - 0.00034 20.7 5.1 0.0019 18.3 5.3 2.1 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 KIY72044.1 - 0.001 19.3 2.6 0.0028 17.9 2.6 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain Tmpp129 PF10272.9 KIY72044.1 - 0.0058 16.0 1.5 0.0076 15.6 1.5 1.2 1 0 0 1 1 1 1 Putative transmembrane protein precursor zf-RING_11 PF17123.5 KIY72044.1 - 0.027 14.2 1.7 0.027 14.2 1.7 1.8 2 0 0 2 2 2 0 RING-like zinc finger zf-RING_10 PF16685.5 KIY72044.1 - 0.042 14.0 3.7 0.39 10.9 3.7 2.1 1 1 0 1 1 1 0 zinc RING finger of MSL2 FYVE PF01363.21 KIY72044.1 - 0.047 13.8 3.8 0.18 11.9 3.8 2.0 1 1 0 1 1 1 0 FYVE zinc finger FANCL_C PF11793.8 KIY72044.1 - 0.079 13.2 2.0 0.17 12.1 2.0 1.6 1 1 0 1 1 1 0 FANCL C-terminal domain Zf_RING PF16744.5 KIY72044.1 - 0.089 12.9 0.7 0.089 12.9 0.7 2.1 1 1 1 2 2 2 0 KIAA1045 RING finger zf-ANAPC11 PF12861.7 KIY72044.1 - 0.1 12.7 1.8 1.4 9.0 1.8 2.3 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger UPF0139 PF03669.13 KIY72046.1 - 4.8e-09 36.0 0.0 6.2e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) LEA_2 PF03168.13 KIY72047.1 - 1.3e-06 28.8 0.1 2.3e-06 28.0 0.1 1.4 1 0 0 1 1 1 1 Late embryogenesis abundant protein Vac7 PF12751.7 KIY72047.1 - 0.26 10.7 0.2 0.58 9.5 0.2 1.6 1 1 0 1 1 1 0 Vacuolar segregation subunit 7 TPK_catalytic PF04263.16 KIY72048.1 - 2e-33 115.0 0.0 3e-33 114.4 0.0 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 KIY72048.1 - 1.2e-19 69.8 0.1 2e-19 69.1 0.1 1.4 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain ThiS PF02597.20 KIY72048.1 - 0.00013 22.5 0.0 0.00024 21.7 0.0 1.4 1 0 0 1 1 1 1 ThiS family DUF726 PF05277.12 KIY72049.1 - 1.4e-94 316.8 2.9 2e-94 316.4 2.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_6 PF12697.7 KIY72049.1 - 0.00078 20.1 2.8 0.009 16.6 0.1 2.4 1 1 0 2 2 2 1 Alpha/beta hydrolase family Cutinase PF01083.22 KIY72049.1 - 0.022 14.7 0.0 0.054 13.4 0.0 1.6 1 0 0 1 1 1 0 Cutinase GHL13 PF14883.6 KIY72049.1 - 0.048 12.7 1.7 0.04 13.0 0.3 1.5 2 0 0 2 2 2 0 Hypothetical glycosyl hydrolase family 13 Lipase_3 PF01764.25 KIY72049.1 - 0.14 12.0 0.0 0.35 10.7 0.0 1.7 2 0 0 2 2 2 0 Lipase (class 3) Sulf_transp PF04143.14 KIY72050.1 - 2.2e-08 34.1 5.4 2.2e-08 34.1 5.4 3.9 2 2 2 4 4 4 2 Sulphur transport zf-RING_5 PF14634.6 KIY72051.1 - 7.8e-08 32.2 5.3 1.4e-07 31.4 5.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain THOC7 PF05615.13 KIY72051.1 - 0.088 13.1 0.1 0.14 12.4 0.1 1.3 1 0 0 1 1 1 0 Tho complex subunit 7 zf-C2HC5 PF06221.13 KIY72051.1 - 2.5 8.2 6.8 5.1 7.2 6.8 1.5 1 1 0 1 1 1 0 Putative zinc finger motif, C2HC5-type zf-RING_UBOX PF13445.6 KIY72051.1 - 8.4 6.5 8.7 18 5.5 8.7 1.6 1 0 0 1 1 1 0 RING-type zinc-finger Glyco_hydro_61 PF03443.14 KIY72052.1 - 6.4e-55 186.3 0.0 8.4e-55 185.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 BHD_2 PF10404.9 KIY72054.1 - 0.074 14.0 1.4 31 5.6 0.3 3.2 3 0 0 3 3 3 0 Rad4 beta-hairpin domain 2 TauD PF02668.16 KIY72057.1 - 9.4e-50 169.9 0.2 1.2e-49 169.5 0.2 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family INCENP_ARK-bind PF03941.15 KIY72058.1 - 1.5e-21 76.0 1.3 1.5e-21 76.0 1.3 2.5 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region Red1 PF07964.11 KIY72058.1 - 0.2 9.9 33.0 0.37 9.0 33.0 1.4 1 0 0 1 1 1 0 Rec10 / Red1 PA26 PF04636.13 KIY72058.1 - 0.51 9.2 10.5 0.15 11.0 7.3 1.5 1 1 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF2968 PF11180.8 KIY72058.1 - 1.4 8.5 15.1 3.3 7.3 15.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) NMT_C PF02799.15 KIY72059.1 - 1.6e-77 259.8 0.0 2.5e-77 259.1 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 KIY72059.1 - 7.3e-75 250.2 0.0 1.1e-74 249.6 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_1 PF00583.25 KIY72059.1 - 0.0013 18.9 0.0 0.0024 18.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 KIY72059.1 - 0.0045 17.1 0.0 0.029 14.4 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KIY72059.1 - 0.047 13.6 0.0 0.093 12.7 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KIY72059.1 - 0.11 13.0 0.0 0.24 11.9 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Gln-synt_C PF00120.24 KIY72060.1 - 1.5e-16 60.3 0.0 4.6e-14 52.2 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 KIY72060.1 - 6.8e-10 38.6 0.0 1.3e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain SLS PF14611.6 KIY72060.1 - 0.14 11.9 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator OGG_N PF07934.12 KIY72061.1 - 1.7e-32 112.1 0.1 2.7e-32 111.4 0.1 1.3 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 KIY72061.1 - 1.1e-14 54.8 0.0 2.7e-14 53.5 0.0 1.6 1 1 1 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein NPR2 PF06218.11 KIY72062.1 - 5.5e-96 322.0 6.1 3.8e-78 263.2 5.0 3.2 1 1 1 2 2 2 2 Nitrogen permease regulator 2 DUF262 PF03235.14 KIY72063.1 - 1.6e-20 74.2 1.2 9.1e-20 71.8 1.2 1.9 1 1 0 1 1 1 1 Protein of unknown function DUF262 ThiF PF00899.21 KIY72064.1 - 9.2e-61 205.3 0.0 1.3e-60 204.8 0.0 1.2 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 KIY72064.1 - 2.4e-26 91.7 1.6 4.1e-26 90.9 1.6 1.4 1 0 0 1 1 1 1 E2 binding domain Shikimate_DH PF01488.20 KIY72064.1 - 0.0033 17.5 0.4 0.01 15.9 0.0 2.0 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase E1_UFD PF09358.10 KIY72064.1 - 0.03 15.0 0.1 0.066 13.9 0.1 1.5 1 0 0 1 1 1 0 Ubiquitin fold domain UDPG_MGDP_dh_N PF03721.14 KIY72064.1 - 0.057 13.0 0.1 0.12 11.9 0.1 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox PF00070.27 KIY72064.1 - 0.057 14.0 0.1 0.12 13.0 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KIY72064.1 - 0.14 12.6 0.0 1.4 9.4 0.0 2.5 2 1 0 2 2 2 0 Putative NAD(P)-binding Peptidase_M36 PF02128.15 KIY72065.1 - 4.6e-162 539.4 2.5 6.1e-162 539.0 2.5 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.13 KIY72065.1 - 6.8e-11 41.8 0.2 1.5e-10 40.8 0.2 1.5 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif UFD1 PF03152.14 KIY72066.1 - 1.1e-70 236.5 0.0 1.4e-70 236.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.17 KIY72066.1 - 0.04 13.7 0.0 0.092 12.5 0.0 1.6 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), domain 2 Cpn60_TCP1 PF00118.24 KIY72067.1 - 3.9e-147 490.8 10.9 4.4e-147 490.6 10.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family zf-MYND PF01753.18 KIY72068.1 - 1.1e-08 35.1 19.1 1.8e-08 34.3 19.1 1.4 1 0 0 1 1 1 1 MYND finger XPG_N PF00752.17 KIY72069.1 - 1.3e-23 83.4 0.0 3.5e-23 82.0 0.0 1.8 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.18 KIY72069.1 - 2.1e-21 76.1 0.0 4.7e-21 74.9 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.7 KIY72069.1 - 1.8e-06 27.6 0.1 3.5e-06 26.7 0.1 1.4 1 0 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.20 KIY72069.1 - 0.011 16.3 0.0 0.044 14.4 0.0 1.9 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold Ribosomal_L3 PF00297.22 KIY72070.1 - 1.1e-20 74.0 1.5 9.3e-19 67.6 1.5 2.3 1 1 0 1 1 1 1 Ribosomal protein L3 Rrn6 PF10214.9 KIY72071.1 - 1.3e-16 60.3 12.6 2.6e-08 32.9 6.1 3.5 3 0 0 3 3 3 3 RNA polymerase I-specific transcription-initiation factor Sugar_tr PF00083.24 KIY72073.1 - 1.2e-114 383.7 19.9 1.4e-114 383.5 19.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY72073.1 - 2.8e-29 102.1 23.1 2.8e-29 102.1 23.1 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KIY72073.1 - 8.4e-07 27.8 3.4 8.4e-07 27.8 3.4 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) PT-VENN PF04829.13 KIY72073.1 - 9 6.5 7.1 1.2 9.3 2.3 2.0 2 0 0 2 2 2 0 Pre-toxin domain with VENN motif Mito_carr PF00153.27 KIY72074.1 - 8.5e-45 150.6 0.6 1.8e-14 53.5 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein F-box-like PF12937.7 KIY72075.1 - 4.6e-06 26.4 1.2 1.9e-05 24.5 1.2 2.1 1 0 0 1 1 1 1 F-box-like Bac_luciferase PF00296.20 KIY72075.1 - 0.01 15.3 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 0 Luciferase-like monooxygenase F-box-like_2 PF13013.6 KIY72075.1 - 0.082 12.9 0.0 0.3 11.1 0.0 2.1 1 0 0 1 1 1 0 F-box-like domain APG17 PF04108.12 KIY72075.1 - 0.22 10.6 7.2 0.75 8.8 0.2 2.6 3 0 0 3 3 3 0 Autophagy protein Apg17 AIM5 PF17050.5 KIY72076.1 - 1.2e-06 29.2 0.0 1.6e-06 28.9 0.0 1.2 1 0 0 1 1 1 1 Altered inheritance of mitochondria 5 Vac_ImportDeg PF09783.9 KIY72077.1 - 2.5e-55 186.7 0.0 3.2e-55 186.4 0.0 1.1 1 0 0 1 1 1 1 Vacuolar import and degradation protein Ribosomal_L26 PF16906.5 KIY72078.1 - 6.2e-37 125.9 3.7 8.8e-37 125.4 3.7 1.2 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 KIY72078.1 - 1.6e-09 37.4 4.6 4.2e-09 36.0 4.2 1.9 2 0 0 2 2 2 1 KOW motif Arena_ncap_C PF17290.2 KIY72078.1 - 0.056 12.8 0.1 0.071 12.4 0.1 1.3 1 0 0 1 1 1 0 Arenavirus nucleocapsid C-terminal domain FRG1 PF06229.12 KIY72079.1 - 2.8e-25 89.2 0.0 4.1e-25 88.6 0.0 1.2 1 0 0 1 1 1 1 FRG1-like domain Fascin PF06268.13 KIY72079.1 - 0.0031 17.7 0.0 0.005 17.0 0.0 1.4 1 0 0 1 1 1 1 Fascin domain BRF1 PF07741.13 KIY72079.1 - 0.87 10.0 8.7 3.8 7.9 4.7 2.4 2 1 0 2 2 2 0 Brf1-like TBP-binding domain DnaJ PF00226.31 KIY72080.1 - 1.7e-16 60.0 0.2 5e-16 58.6 0.2 1.8 1 0 0 1 1 1 1 DnaJ domain Ank_4 PF13637.6 KIY72080.1 - 1.4e-11 44.7 0.0 1.5e-08 35.0 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KIY72080.1 - 3.1e-10 40.5 0.0 8.8e-10 39.0 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KIY72080.1 - 1.8e-09 37.7 0.0 0.00012 22.3 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIY72080.1 - 1.6e-08 34.1 0.0 0.0027 18.1 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 KIY72080.1 - 1.9e-06 28.0 0.0 0.0099 16.3 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat V_ATPase_I PF01496.19 KIY72080.1 - 0.56 8.1 6.2 1.1 7.1 6.2 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RNA_polI_A34 PF08208.11 KIY72080.1 - 1.9 8.5 19.1 0.18 11.9 14.0 1.9 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 NPR3 PF03666.13 KIY72080.1 - 4.2 6.1 8.1 7.8 5.2 8.1 1.4 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DDHD PF02862.17 KIY72080.1 - 7.5 6.6 8.7 1.7 8.7 4.0 2.0 2 0 0 2 2 2 0 DDHD domain Oxidored_FMN PF00724.20 KIY72081.1 - 4.3e-95 318.9 0.0 4.9e-95 318.7 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family GMC_oxred_C PF05199.13 KIY72082.1 - 2e-08 34.8 0.1 4.1e-08 33.9 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase PIG-L PF02585.17 KIY72082.1 - 0.12 13.0 0.0 0.26 11.9 0.0 1.6 1 0 0 1 1 1 0 GlcNAc-PI de-N-acetylase Pkinase PF00069.25 KIY72084.1 - 3.2e-28 98.8 0.0 5.2e-28 98.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY72084.1 - 2.3e-10 40.2 0.0 7.6e-10 38.5 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KIY72084.1 - 0.00019 21.4 0.1 0.00032 20.7 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KIY72084.1 - 0.018 14.4 0.1 0.027 13.8 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KIY72084.1 - 0.052 13.1 0.0 0.14 11.7 0.0 1.8 2 0 0 2 2 2 0 RIO1 family Choline_kinase PF01633.20 KIY72084.1 - 0.13 11.9 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase BCS1_N PF08740.11 KIY72085.1 - 1e-35 123.4 3.4 1.6e-35 122.8 3.4 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 KIY72085.1 - 5.4e-17 62.4 0.0 1.1e-16 61.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KIY72085.1 - 0.00018 21.9 0.2 0.0013 19.1 0.1 2.3 2 1 0 2 2 1 1 AAA ATPase domain AAA_33 PF13671.6 KIY72085.1 - 0.00026 21.2 0.1 0.001 19.2 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KIY72085.1 - 0.006 17.1 0.0 0.022 15.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KIY72085.1 - 0.019 14.7 0.0 0.035 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KIY72085.1 - 0.02 14.9 0.0 0.041 13.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KIY72085.1 - 0.022 14.5 0.0 0.038 13.7 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 KIY72085.1 - 0.022 15.0 0.0 0.11 12.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KIY72085.1 - 0.026 14.8 0.1 0.11 12.7 0.0 2.1 2 1 1 3 3 2 0 AAA domain TsaE PF02367.17 KIY72085.1 - 0.03 14.3 0.0 0.061 13.3 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 KIY72085.1 - 0.04 13.6 0.1 0.52 10.0 0.0 2.4 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KIY72085.1 - 0.058 13.9 0.0 0.13 12.8 0.0 1.6 1 0 0 1 1 1 0 ABC transporter DUF815 PF05673.13 KIY72085.1 - 0.063 12.4 0.0 0.16 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Rad17 PF03215.15 KIY72085.1 - 0.078 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_29 PF13555.6 KIY72085.1 - 0.1 12.4 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.12 KIY72085.1 - 0.11 12.4 0.0 0.25 11.2 0.0 1.6 1 1 0 1 1 1 0 NACHT domain AAA_17 PF13207.6 KIY72085.1 - 0.14 12.6 0.1 0.85 10.1 0.0 2.2 1 1 1 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 KIY72085.1 - 0.15 11.8 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF4420 PF14390.6 KIY72085.1 - 0.16 11.1 0.3 0.27 10.5 0.3 1.3 1 0 0 1 1 1 0 Putative PD-(D/E)XK family member, (DUF4420) Lipase_GDSL_3 PF14606.6 KIY72085.1 - 0.17 12.0 0.0 0.32 11.1 0.0 1.4 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family TIP49 PF06068.13 KIY72085.1 - 0.17 11.1 0.0 0.26 10.5 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain ATPase PF06745.13 KIY72085.1 - 0.17 11.2 0.0 0.34 10.2 0.0 1.4 1 0 0 1 1 1 0 KaiC RNA_helicase PF00910.22 KIY72085.1 - 0.2 12.1 0.0 0.33 11.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase ATP-synt_D PF01813.17 KIY72087.1 - 1.5e-72 243.6 3.9 1.8e-72 243.3 3.9 1.1 1 0 0 1 1 1 1 ATP synthase subunit D HtrL_YibB PF09612.10 KIY72087.1 - 0.061 12.8 0.1 0.09 12.3 0.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (HtrL_YibB) MFS_1 PF07690.16 KIY72089.1 - 4e-16 58.9 32.8 4e-16 58.9 32.8 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 KIY72089.1 - 2.5e-13 50.0 5.5 2.5e-13 50.0 5.5 2.1 2 1 1 3 3 3 1 Ion channel regulatory protein UNC-93 F-box-like PF12937.7 KIY72090.1 - 2.5e-07 30.5 1.4 4.9e-07 29.5 0.3 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIY72090.1 - 0.028 14.3 0.7 1.7 8.6 0.6 2.9 2 0 0 2 2 2 0 F-box domain bPH_6 PF10756.9 KIY72090.1 - 0.072 13.2 0.1 0.072 13.2 0.1 2.9 3 0 0 3 3 3 0 Bacterial PH domain MFS_1 PF07690.16 KIY72091.1 - 9.4e-50 169.5 45.4 1.5e-49 168.8 45.4 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KIY72091.1 - 4.4e-21 74.9 13.7 6.4e-21 74.4 13.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KIY72091.1 - 5.9e-11 41.9 13.1 5.9e-11 41.9 13.1 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter DUF3611 PF12263.8 KIY72091.1 - 0.018 14.9 1.4 0.018 14.9 1.4 2.5 3 1 1 4 4 4 0 Protein of unknown function (DUF3611) HlyIII PF03006.20 KIY72091.1 - 0.066 12.9 0.2 0.066 12.9 0.2 3.3 2 1 1 3 3 3 0 Haemolysin-III related PhoLip_ATPase_C PF16212.5 KIY72091.1 - 1.8 8.2 7.0 0.39 10.4 1.9 2.4 1 1 2 3 3 3 0 Phospholipid-translocating P-type ATPase C-terminal Ras PF00071.22 KIY72092.1 - 2e-50 170.6 0.0 2.4e-50 170.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIY72092.1 - 4.3e-30 104.4 0.1 7.7e-30 103.6 0.0 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIY72092.1 - 3.8e-10 39.5 0.0 5.2e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KIY72092.1 - 0.00029 20.3 0.0 0.00038 19.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KIY72092.1 - 0.0021 18.1 0.0 0.0038 17.3 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 KIY72092.1 - 0.0066 16.8 0.1 0.059 13.8 0.1 2.1 1 1 0 1 1 1 1 RNA helicase G-alpha PF00503.20 KIY72092.1 - 0.014 14.6 2.0 1.2 8.2 0.2 2.6 2 1 0 2 2 2 0 G-protein alpha subunit Pox_A32 PF04665.12 KIY72092.1 - 0.022 14.2 0.1 0.038 13.5 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein RsgA_GTPase PF03193.16 KIY72092.1 - 0.022 14.7 0.0 7.7 6.4 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_7 PF12775.7 KIY72092.1 - 0.025 14.1 0.0 0.04 13.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 KIY72092.1 - 0.044 13.5 0.1 0.072 12.8 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KIY72092.1 - 0.06 13.5 0.5 0.22 11.7 0.2 1.9 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KIY72092.1 - 0.081 13.3 0.2 0.11 12.9 0.2 1.6 1 1 0 1 1 1 0 AAA ATPase domain TsaE PF02367.17 KIY72092.1 - 0.12 12.4 0.1 0.24 11.4 0.1 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE STAS PF01740.21 KIY72092.1 - 0.13 11.9 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 STAS domain Septin PF00735.18 KIY72092.1 - 0.14 11.4 0.0 0.28 10.4 0.0 1.5 1 0 0 1 1 1 0 Septin LUC7 PF03194.15 KIY72093.1 - 7.2e-71 238.8 5.9 9.7e-71 238.4 5.9 1.1 1 0 0 1 1 1 1 LUC7 N_terminus DUF3418 PF11898.8 KIY72093.1 - 0.058 12.1 0.1 0.083 11.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3418) UCH PF00443.29 KIY72095.1 - 3.2e-36 125.2 2.3 3.3e-36 125.1 0.4 2.0 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KIY72095.1 - 2e-18 67.1 1.0 2.1e-17 63.7 1.0 2.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 KIY72095.1 - 4.4e-06 26.4 0.2 1.2e-05 25.0 0.2 1.7 1 0 0 1 1 1 1 Ubiquitin family DUSP PF06337.12 KIY72095.1 - 0.00055 20.5 0.0 0.29 11.8 0.0 3.1 2 0 0 2 2 2 1 DUSP domain Latexin PF06907.12 KIY72095.1 - 0.016 14.7 0.6 0.031 13.8 0.6 1.4 1 0 0 1 1 1 0 Latexin Rad60-SLD PF11976.8 KIY72095.1 - 0.087 12.7 0.2 0.2 11.5 0.2 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF3470 PF11953.8 KIY72095.1 - 0.12 12.3 2.7 0.37 10.8 2.7 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3470) Gaa1 PF04114.14 KIY72096.1 - 2.4e-91 307.3 12.0 2.3e-89 300.7 12.0 2.1 1 1 0 1 1 1 1 Gaa1-like, GPI transamidase component NAD_binding_10 PF13460.6 KIY72097.1 - 5.9e-10 39.3 0.0 7.8e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KIY72097.1 - 2.6e-08 33.7 0.0 3.8e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.24 KIY72097.1 - 2e-05 25.0 0.0 4.3e-05 23.9 0.0 1.6 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KIY72097.1 - 2.2e-05 24.7 0.0 4.2e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_4 PF07993.12 KIY72097.1 - 0.00027 20.2 0.1 0.017 14.3 0.1 2.2 2 0 0 2 2 2 1 Male sterility protein DapB_N PF01113.20 KIY72097.1 - 0.003 17.7 0.0 0.0057 16.8 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.21 KIY72097.1 - 0.004 16.6 0.1 0.057 12.9 0.1 2.5 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 KIY72097.1 - 0.026 14.8 0.2 0.054 13.8 0.2 1.5 1 0 0 1 1 1 0 TrkA-N domain KR PF08659.10 KIY72097.1 - 0.036 14.0 0.1 0.061 13.2 0.1 1.3 1 0 0 1 1 1 0 KR domain Ras PF00071.22 KIY72098.1 - 2.9e-43 147.3 0.9 3.3e-43 147.1 0.9 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIY72098.1 - 1.1e-12 48.2 0.1 1.7e-12 47.6 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIY72098.1 - 3.2e-05 23.4 0.0 4e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KIY72098.1 - 9.9e-05 22.3 0.3 0.035 14.0 0.1 2.1 1 1 1 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KIY72098.1 - 0.00021 21.3 0.0 0.00041 20.4 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 KIY72098.1 - 0.01 15.9 0.2 0.024 14.6 0.1 1.6 1 1 0 2 2 2 1 C-terminal region of MMR_HSR1 domain AAA_14 PF13173.6 KIY72098.1 - 0.012 15.7 0.0 0.02 14.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KIY72098.1 - 0.029 14.3 0.1 0.046 13.6 0.1 1.5 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_28 PF13521.6 KIY72098.1 - 0.045 14.0 0.0 0.22 11.7 0.0 2.0 2 1 0 2 2 2 0 AAA domain RNase_H_2 PF13482.6 KIY72098.1 - 0.051 13.6 0.0 0.063 13.3 0.0 1.3 1 1 0 1 1 1 0 RNase_H superfamily Tom37 PF10568.9 KIY72099.1 - 2e-21 76.6 0.4 3.3e-21 75.9 0.4 1.4 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_6 PF17171.4 KIY72099.1 - 1.2e-09 37.9 0.0 2.8e-09 36.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KIY72099.1 - 1.1e-05 26.1 0.0 2e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_2 PF13410.6 KIY72099.1 - 0.0001 22.3 0.0 0.00022 21.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF1996 PF09362.10 KIY72101.1 - 1.4e-80 270.7 1.3 1.7e-80 270.4 1.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) XAP5 PF04921.14 KIY72102.1 - 3.5e-84 282.5 0.5 3.5e-84 282.5 0.5 1.7 1 1 1 2 2 2 1 XAP5, circadian clock regulator NST1 PF13945.6 KIY72102.1 - 0.0085 16.2 3.2 0.0085 16.2 3.2 1.6 2 0 0 2 2 2 1 Salt tolerance down-regulator Ribosomal_S13 PF00416.22 KIY72103.1 - 2.9e-20 72.9 0.0 5.4e-10 39.8 0.5 2.1 2 0 0 2 2 2 2 Ribosomal protein S13/S18 TRAPP PF04051.16 KIY72104.1 - 4.4e-36 123.8 0.0 5.3e-36 123.5 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component WBS_methylT PF12589.8 KIY72105.1 - 7e-22 78.0 7.2 1.3e-21 77.1 7.2 1.5 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 KIY72105.1 - 5.4e-09 36.6 0.0 9.6e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIY72105.1 - 1.1e-07 32.4 0.0 2e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIY72105.1 - 0.00013 22.6 0.0 0.00038 21.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIY72105.1 - 0.0002 21.2 0.0 0.0003 20.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIY72105.1 - 0.0083 15.9 0.0 0.016 15.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain AdoMet_MTase PF07757.13 KIY72105.1 - 0.011 16.1 0.0 0.021 15.2 0.0 1.5 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase F-box-like PF12937.7 KIY72106.1 - 9.6e-09 35.0 0.2 2.4e-08 33.7 0.2 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY72106.1 - 0.0031 17.3 4.5 0.079 12.9 0.1 2.7 2 0 0 2 2 2 2 F-box domain Snf7 PF03357.21 KIY72107.1 - 5.9e-22 78.1 4.5 8.4e-22 77.6 4.5 1.2 1 0 0 1 1 1 1 Snf7 FapA PF03961.13 KIY72107.1 - 0.037 12.6 0.2 0.063 11.9 0.2 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A Snapin_Pallidin PF14712.6 KIY72107.1 - 0.13 12.7 1.2 0.37 11.2 0.1 2.3 2 0 0 2 2 2 0 Snapin/Pallidin DUF677 PF05055.12 KIY72107.1 - 0.29 10.0 3.5 0.14 11.0 1.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF677) SlyX PF04102.12 KIY72107.1 - 0.4 11.3 2.8 0.84 10.3 0.0 2.9 4 0 0 4 4 4 0 SlyX CLPTM1 PF05602.12 KIY72108.1 - 4.4e-148 493.9 0.0 5.4e-148 493.6 0.0 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.14 KIY72108.1 - 0.00042 20.0 0.9 0.003 17.3 0.2 2.5 3 0 0 3 3 3 1 PQ loop repeat 2TM PF13239.6 KIY72108.1 - 9.9 6.5 7.1 3.2 8.1 0.9 2.9 3 0 0 3 3 3 0 2TM domain HSP9_HSP12 PF04119.12 KIY72109.1 - 6.3e-24 84.1 7.5 8.7e-24 83.7 7.5 1.2 1 0 0 1 1 1 1 Heat shock protein 9/12 DUF3524 PF12038.8 KIY72109.1 - 0.24 11.2 0.0 0.46 10.3 0.0 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3524) Podoplanin PF05808.11 KIY72110.1 - 0.00084 19.5 0.2 0.14 12.3 0.0 2.2 2 0 0 2 2 2 2 Podoplanin BatA PF07584.11 KIY72110.1 - 0.0022 18.3 0.0 0.0046 17.3 0.0 1.4 1 0 0 1 1 1 1 Aerotolerance regulator N-terminal DUF5337 PF17272.2 KIY72110.1 - 0.1 12.5 0.4 0.17 11.7 0.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5337) Gram_pos_anchor PF00746.21 KIY72110.1 - 3.4 7.7 4.5 6.3 6.8 4.2 1.7 1 1 0 1 1 1 0 LPXTG cell wall anchor motif Ribosomal_L30_N PF08079.12 KIY72111.1 - 1.3e-26 92.6 16.2 2.4e-26 91.8 16.2 1.4 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 KIY72111.1 - 2.7e-18 65.6 1.3 2.7e-18 65.6 1.3 1.8 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e Tipalpha PF16753.5 KIY72111.1 - 0.053 13.3 0.4 0.23 11.3 0.1 2.0 1 1 1 2 2 2 0 TNF-alpha-Inducing protein of Helicobacter Exo_endo_phos PF03372.23 KIY72112.1 - 2.2e-09 37.2 0.1 5.3e-09 35.9 0.1 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Pro_CA PF00484.19 KIY72113.1 - 2.7e-40 138.2 0.0 3.8e-40 137.7 0.0 1.2 1 0 0 1 1 1 1 Carbonic anhydrase Fer4_10 PF13237.6 KIY72113.1 - 0.001 19.1 0.7 0.0016 18.5 0.7 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 KIY72113.1 - 0.0031 17.6 1.3 0.006 16.7 1.3 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 KIY72113.1 - 0.0054 17.3 0.5 0.011 16.3 0.5 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 KIY72113.1 - 0.0084 16.3 1.0 0.012 15.7 0.4 1.7 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4 PF00037.27 KIY72113.1 - 0.011 15.5 3.2 0.025 14.4 3.2 1.6 1 0 0 1 1 1 0 4Fe-4S binding domain Fer4_8 PF13183.6 KIY72113.1 - 0.04 14.4 0.7 0.064 13.7 0.7 1.4 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_15 PF13459.6 KIY72113.1 - 0.053 14.3 1.2 0.12 13.1 1.2 1.6 1 0 0 1 1 1 0 4Fe-4S single cluster domain Fer4_2 PF12797.7 KIY72113.1 - 0.089 12.9 2.8 0.25 11.5 2.8 1.9 1 0 0 1 1 1 0 4Fe-4S binding domain Fer4_6 PF12837.7 KIY72113.1 - 0.47 10.6 5.1 1.1 9.4 5.1 1.6 1 0 0 1 1 1 0 4Fe-4S binding domain MFS_1 PF07690.16 KIY72114.1 - 2.5e-27 95.7 22.8 3.5e-20 72.2 16.1 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIY72114.1 - 0.00017 20.6 9.7 0.0005 19.1 5.1 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter Complex1_LYR PF05347.15 KIY72115.1 - 5.8e-09 35.9 0.2 7.9e-09 35.4 0.2 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KIY72115.1 - 0.0025 18.5 0.1 0.0028 18.4 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Cofilin_ADF PF00241.20 KIY72116.1 - 2e-19 69.6 0.0 2.2e-19 69.4 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SRPRB PF09439.10 KIY72117.1 - 1.1e-21 77.1 0.0 1.8e-21 76.4 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 KIY72117.1 - 2.8e-13 49.7 0.0 4.2e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KIY72117.1 - 8.3e-10 38.4 0.0 1.1e-09 38.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KIY72117.1 - 1e-09 38.5 0.0 1.6e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KIY72117.1 - 8.1e-06 25.5 0.1 0.0014 18.2 0.1 2.2 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain Roc PF08477.13 KIY72117.1 - 2.7e-05 24.3 0.0 4.7e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 KIY72117.1 - 0.0018 17.8 0.0 0.0072 15.9 0.0 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KIY72117.1 - 0.0026 17.8 0.0 2.6 8.1 0.0 2.4 1 1 1 2 2 2 2 Dynamin family G-alpha PF00503.20 KIY72117.1 - 0.0032 16.7 0.0 1.3 8.1 0.0 2.1 1 1 0 2 2 2 2 G-protein alpha subunit Ras PF00071.22 KIY72117.1 - 0.022 14.3 0.0 0.031 13.9 0.0 1.2 1 0 0 1 1 1 0 Ras family AAA_16 PF13191.6 KIY72117.1 - 0.026 14.9 0.1 0.045 14.1 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain TniB PF05621.11 KIY72117.1 - 0.045 13.2 0.0 0.094 12.1 0.0 1.6 1 1 1 2 2 2 0 Bacterial TniB protein AAA_7 PF12775.7 KIY72117.1 - 0.067 12.7 0.0 0.63 9.5 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region Hpt PF01627.23 KIY72118.1 - 6.8e-10 39.1 1.2 7.3e-10 39.0 0.2 1.5 2 0 0 2 2 2 1 Hpt domain zf-C2HC5 PF06221.13 KIY72119.1 - 8.8e-14 51.2 4.8 1.3e-13 50.7 4.8 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type zf-ribbon_3 PF13248.6 KIY72119.1 - 0.0035 16.7 1.0 1.7 8.2 0.1 2.4 2 0 0 2 2 2 2 zinc-ribbon domain DZR PF12773.7 KIY72119.1 - 0.32 11.1 4.7 0.66 10.1 4.7 1.6 1 0 0 1 1 1 0 Double zinc ribbon zf-dskA_traR PF01258.17 KIY72119.1 - 1.9 8.5 4.9 0.49 10.4 0.4 2.2 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger Utp21 PF04192.12 KIY72120.1 - 1.1e-62 211.6 0.9 1.7e-62 211.0 0.9 1.3 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain ANAPC4_WD40 PF12894.7 KIY72120.1 - 2e-17 63.3 0.0 5.1e-07 29.9 0.0 5.8 2 2 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KIY72120.1 - 1.6e-15 57.2 13.5 0.0015 19.3 0.0 9.5 10 0 0 10 10 10 3 WD domain, G-beta repeat PQQ_2 PF13360.6 KIY72120.1 - 4.6e-06 26.4 0.2 4.3e-05 23.2 0.0 2.4 2 0 0 2 2 2 1 PQQ-like domain Nup160 PF11715.8 KIY72120.1 - 0.0039 15.9 3.6 0.045 12.4 0.3 3.1 2 2 1 3 3 3 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KIY72120.1 - 0.0043 15.8 2.0 5.2 5.7 0.0 4.5 4 1 1 5 5 5 1 Nup133 N terminal like RAB3GAP2_N PF14655.6 KIY72120.1 - 0.016 14.5 0.1 1.7 7.8 0.0 2.9 2 1 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus ELYS-bb PF16687.5 KIY72120.1 - 0.031 12.9 0.1 2.1 6.9 0.0 2.4 1 1 1 2 2 2 0 beta-propeller of ELYS nucleoporin PQQ PF01011.21 KIY72120.1 - 0.033 14.1 0.0 15 5.7 0.0 4.1 3 1 0 3 3 3 0 PQQ enzyme repeat Cytochrom_D1 PF02239.16 KIY72120.1 - 0.035 12.7 0.0 6.4 5.2 0.1 3.0 2 1 1 3 3 3 0 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 KIY72120.1 - 0.28 10.1 0.5 29 3.5 0.0 3.8 3 2 2 5 5 5 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Fungal_trans PF04082.18 KIY72122.1 - 5.6e-20 71.5 0.1 7.4e-20 71.1 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Rft-1 PF04506.13 KIY72123.1 - 9.3e-117 390.9 5.6 1.1e-116 390.6 5.6 1.0 1 0 0 1 1 1 1 Rft protein Polysacc_synt_3 PF13440.6 KIY72123.1 - 1.1e-06 28.1 10.0 0.00026 20.3 0.1 3.1 3 0 0 3 3 3 3 Polysaccharide biosynthesis protein Polysacc_synt PF01943.17 KIY72123.1 - 7.9e-05 22.2 0.1 7.9e-05 22.2 0.1 3.0 3 1 1 4 4 4 2 Polysaccharide biosynthesis protein iPGM_N PF06415.13 KIY72124.1 - 4.3e-78 261.7 0.1 6.7e-78 261.0 0.1 1.3 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Metalloenzyme PF01676.18 KIY72124.1 - 2.7e-71 239.8 1.3 3.1e-71 239.6 1.3 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 KIY72124.1 - 3e-07 30.2 0.0 3.2e-06 26.8 0.0 2.3 1 1 0 1 1 1 1 Sulfatase PglZ PF08665.12 KIY72124.1 - 0.034 14.3 0.0 0.086 12.9 0.0 1.6 2 0 0 2 2 2 0 PglZ domain IF2_N PF04760.15 KIY72127.1 - 0.097 12.5 0.0 0.29 11.0 0.0 1.8 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region DEAD PF00270.29 KIY72128.1 - 1.8e-09 37.6 0.0 8e-09 35.5 0.0 2.1 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIY72128.1 - 6.5e-08 32.9 0.0 2.8e-07 30.8 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SAP PF02037.27 KIY72128.1 - 1.2e-05 24.9 0.0 4e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 SAP domain HMA PF00403.26 KIY72129.1 - 1.6e-10 41.3 0.8 2.3e-10 40.7 0.8 1.3 1 0 0 1 1 1 1 Heavy-metal-associated domain DUF2140 PF09911.9 KIY72129.1 - 0.037 13.6 0.0 0.042 13.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) Ribosomal_L44 PF00935.19 KIY72129.1 - 0.057 13.9 0.3 0.95 10.0 0.1 2.0 2 0 0 2 2 2 0 Ribosomal protein L44 AA_permease_2 PF13520.6 KIY72130.1 - 2.2e-61 208.0 37.6 2.7e-61 207.7 37.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KIY72130.1 - 7.8e-26 90.7 35.2 1.4e-25 89.9 35.0 1.4 1 1 0 1 1 1 1 Amino acid permease DUF872 PF05915.12 KIY72130.1 - 0.35 11.0 8.9 31 4.8 1.0 4.4 4 1 0 4 4 4 0 Eukaryotic protein of unknown function (DUF872) Sdh_cyt PF01127.22 KIY72131.1 - 1.7e-23 82.9 0.8 2.3e-23 82.5 0.8 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit TRM PF02005.16 KIY72132.1 - 2.7e-92 309.8 0.3 5.6e-76 256.2 0.2 2.0 1 1 1 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.16 KIY72132.1 - 0.049 13.4 0.0 0.075 12.8 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein tRNA_U5-meth_tr PF05958.11 KIY72132.1 - 0.15 11.0 0.0 0.21 10.5 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase TRM PF02005.16 KIY72133.1 - 1.2e-119 399.9 0.0 1.4e-119 399.6 0.0 1.0 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.16 KIY72133.1 - 0.0078 16.0 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_25 PF13649.6 KIY72133.1 - 0.048 14.4 0.0 0.13 12.9 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain HypA PF01155.19 KIY72133.1 - 0.14 12.1 0.6 24 5.0 0.1 2.5 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn-ribbon_8 PF09723.10 KIY72133.1 - 0.68 10.1 2.1 5.8 7.1 2.1 2.3 1 1 0 1 1 1 0 Zinc ribbon domain SNF2_N PF00176.23 KIY72134.1 - 2.3e-51 174.6 0.0 3.7e-51 173.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KIY72134.1 - 2.6e-18 66.4 0.0 1.5e-17 63.9 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIY72134.1 - 6.6e-07 29.5 0.0 1.4e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KIY72134.1 - 0.00024 20.4 0.0 0.00046 19.5 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase RLAN PF14401.6 KIY72134.1 - 0.0021 17.7 0.0 0.013 15.2 0.0 2.3 3 0 0 3 3 3 1 RimK-like ATPgrasp N-terminal domain zf-RING_5 PF14634.6 KIY72134.1 - 0.0034 17.3 1.4 0.0091 15.9 1.4 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-UDP PF14569.6 KIY72134.1 - 0.0043 17.1 4.6 1.4 9.1 1.1 3.5 2 1 1 3 3 2 2 Zinc-binding RING-finger zf-C3HC4 PF00097.25 KIY72134.1 - 0.0051 16.7 2.6 0.032 14.1 2.6 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.21 KIY72134.1 - 0.059 13.5 1.3 0.12 12.5 1.3 1.4 1 0 0 1 1 1 0 FYVE zinc finger zf-RING_UBOX PF13445.6 KIY72134.1 - 0.064 13.3 0.5 0.15 12.1 0.5 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.6 KIY72134.1 - 0.096 13.0 3.3 0.11 12.8 0.7 2.3 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4_2 PF13923.6 KIY72134.1 - 0.1 12.4 5.5 0.041 13.7 1.4 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 KIY72134.1 - 0.26 11.1 4.5 46 3.9 0.0 3.4 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 KIY72134.1 - 0.26 11.2 8.0 0.65 9.9 0.4 3.1 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KIY72134.1 - 0.33 10.9 5.4 0.26 11.2 1.5 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Fcf1 PF04900.12 KIY72135.1 - 2.2e-36 124.2 0.1 3.8e-36 123.5 0.1 1.4 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 KIY72135.1 - 3.9e-05 23.9 0.0 6e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 PIN like domain DUF2012 PF09430.10 KIY72136.1 - 2.1e-19 69.8 0.2 3.2e-19 69.3 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) fn3_3 PF14686.6 KIY72136.1 - 0.01 15.6 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide lyase family 4, domain II SOP4 PF17081.5 KIY72136.1 - 0.023 14.2 0.0 0.036 13.6 0.0 1.3 1 0 0 1 1 1 0 Suppressor of PMA 1-7 protein Hus1 PF04005.12 KIY72138.1 - 2.8e-77 259.7 1.0 3.2e-77 259.5 1.0 1.0 1 0 0 1 1 1 1 Hus1-like protein PCNA_C PF02747.15 KIY72138.1 - 0.00034 20.8 0.5 0.00065 19.9 0.5 1.5 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain Rad1 PF02144.16 KIY72138.1 - 0.031 13.3 0.2 0.037 13.1 0.2 1.3 1 0 0 1 1 1 0 Repair protein Rad1/Rec1/Rad17 Pet20 PF08692.10 KIY72138.1 - 0.15 12.8 0.1 0.29 11.8 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial protein Pet20 Dynamin_N PF00350.23 KIY72139.1 - 7.3e-26 91.2 0.0 1.7e-25 90.0 0.0 1.7 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KIY72139.1 - 1.7e-14 53.8 0.0 3.3e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 Dynamin central region GED PF02212.18 KIY72139.1 - 2.9e-10 40.2 0.5 2.9e-10 40.2 0.5 2.0 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KIY72139.1 - 5.9e-05 23.1 1.2 0.0018 18.3 1.2 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.6 KIY72139.1 - 0.019 15.2 0.1 0.06 13.6 0.1 1.9 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KIY72139.1 - 0.098 12.4 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 KIY72139.1 - 0.11 12.9 0.1 0.61 10.4 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain Fer4_NifH PF00142.18 KIY72139.1 - 0.13 11.7 0.1 0.38 10.2 0.0 1.8 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CE2_N PF17996.1 KIY72141.1 - 9.4e-05 22.4 1.4 0.0016 18.4 0.1 2.8 3 0 0 3 3 3 1 Carbohydrate esterase 2 N-terminal Selenoprotein_S PF06936.11 KIY72141.1 - 1.3 8.8 4.8 0.7 9.7 2.1 1.8 2 0 0 2 2 2 0 Selenoprotein S (SelS) Big_2 PF02368.18 KIY72141.1 - 2.5 8.0 5.8 1.5 8.7 3.1 2.1 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 2) CFEM PF05730.11 KIY72142.1 - 1.5e-09 37.8 23.7 7e-06 26.0 2.8 3.0 3 0 0 3 3 3 2 CFEM domain DPM2 PF07297.12 KIY72143.1 - 4.2e-26 91.0 1.4 4.8e-26 90.9 1.4 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.12 KIY72143.1 - 2.1e-06 27.6 0.6 2.2e-06 27.6 0.6 1.1 1 0 0 1 1 1 1 PIG-P Phage_holin_3_6 PF07332.11 KIY72143.1 - 0.16 12.0 1.8 0.19 11.8 1.8 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III TRAPPC9-Trs120 PF08626.11 KIY72144.1 - 1.6e-192 641.9 0.0 1.9e-191 638.4 0.0 2.1 1 1 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Ald_Xan_dh_C2 PF02738.18 KIY72144.1 - 0.22 9.9 0.1 0.36 9.2 0.1 1.2 1 0 0 1 1 1 0 Molybdopterin-binding domain of aldehyde dehydrogenase RRM_1 PF00076.22 KIY72145.1 - 9e-15 54.3 0.2 3.6e-14 52.3 0.2 1.9 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KIY72145.1 - 0.00024 21.2 0.0 0.0003 20.9 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif RRM_occluded PF16842.5 KIY72145.1 - 0.0071 16.2 0.0 3 7.8 0.0 2.1 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_5 PF13893.6 KIY72145.1 - 0.054 13.1 0.1 0.1 12.2 0.1 1.4 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2040 PF09745.9 KIY72146.1 - 1.5e-37 128.3 20.3 1.5e-37 128.3 20.3 2.8 2 1 0 2 2 2 1 Coiled-coil domain-containing protein 55 (DUF2040) RNase_PH PF01138.21 KIY72147.1 - 5.5e-31 107.8 0.1 8.4e-31 107.2 0.1 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KIY72147.1 - 0.012 15.7 0.0 0.02 14.9 0.0 1.4 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 B12-binding_2 PF02607.17 KIY72147.1 - 0.048 14.1 0.0 0.076 13.5 0.0 1.4 1 0 0 1 1 1 0 B12 binding domain dCache_3 PF14827.6 KIY72147.1 - 0.092 12.4 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Double sensory domain of two-component sensor kinase Tropomyosin PF00261.20 KIY72148.1 - 0.0026 17.2 17.7 0.0026 17.2 17.7 2.8 2 1 0 2 2 2 1 Tropomyosin Tup_N PF08581.10 KIY72148.1 - 0.0028 17.9 7.9 0.34 11.2 0.0 4.4 3 1 0 3 3 3 1 Tup N-terminal Fez1 PF06818.15 KIY72148.1 - 0.0051 17.3 5.8 0.0051 17.3 5.8 4.0 2 1 2 4 4 4 1 Fez1 LPP PF04728.13 KIY72148.1 - 0.0063 16.9 8.9 0.62 10.5 0.1 4.8 4 0 0 4 4 4 1 Lipoprotein leucine-zipper Tho2 PF11262.8 KIY72148.1 - 0.019 14.2 1.9 0.043 13.0 1.9 1.6 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 BST2 PF16716.5 KIY72148.1 - 0.032 14.8 1.5 0.032 14.8 1.5 4.8 6 0 0 6 6 4 0 Bone marrow stromal antigen 2 IFT57 PF10498.9 KIY72148.1 - 0.1 11.5 10.0 0.69 8.8 0.1 3.1 4 0 0 4 4 4 0 Intra-flagellar transport protein 57 HATPase_c_2 PF13581.6 KIY72148.1 - 0.27 11.2 1.7 1.2 9.1 0.1 2.9 4 0 0 4 4 3 0 Histidine kinase-like ATPase domain CCDC144C PF14915.6 KIY72148.1 - 0.37 9.8 21.3 0.52 9.4 6.1 3.6 2 2 1 3 3 3 0 CCDC144C protein coiled-coil region DUF1192 PF06698.11 KIY72148.1 - 0.39 10.8 4.6 20 5.4 0.4 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) Zein-binding PF04576.15 KIY72148.1 - 0.44 10.9 13.6 0.13 12.6 4.2 3.3 3 0 0 3 3 3 0 Zein-binding TSC22 PF01166.18 KIY72148.1 - 0.72 10.2 3.5 14 6.1 0.3 3.4 3 0 0 3 3 3 0 TSC-22/dip/bun family Fungal_TACC PF12709.7 KIY72148.1 - 2.2 8.8 8.8 6.7 7.2 0.1 4.0 4 1 0 4 4 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins Seryl_tRNA_N PF02403.22 KIY72148.1 - 2.4 8.4 16.5 0.2 11.9 1.7 3.8 3 2 1 4 4 3 0 Seryl-tRNA synthetase N-terminal domain TRAF_BIRC3_bd PF16673.5 KIY72148.1 - 5.2 6.9 6.4 25 4.8 0.6 3.3 3 0 0 3 3 3 0 TNF receptor-associated factor BIRC3 binding domain CC2-LZ PF16516.5 KIY72148.1 - 5.2 7.5 15.7 6.5 7.2 1.1 4.8 4 0 0 4 4 4 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator SHE3 PF17078.5 KIY72148.1 - 7 6.3 15.9 0.17 11.5 3.5 2.7 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 YPEB PF14620.6 KIY72148.1 - 7.6 5.8 14.7 1.5 8.1 0.6 3.3 2 1 1 3 3 3 0 YpeB sporulation DUF4391 PF14335.6 KIY72148.1 - 9.1 5.9 10.2 0.78 9.4 0.9 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4391) DUF5082 PF16888.5 KIY72148.1 - 9.4 6.5 13.7 0.15 12.3 3.4 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) DUF4211 PF13926.6 KIY72149.1 - 1.9e-27 96.1 0.1 5.8e-27 94.5 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4211) Bim_N PF06773.11 KIY72151.1 - 0.0073 16.0 6.9 0.0073 16.0 6.9 3.8 7 0 0 7 7 7 1 Bim protein N-terminus TFIID-18kDa PF02269.16 KIY72152.1 - 1.4e-20 73.1 0.0 1.7e-20 72.8 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit F-box-like PF12937.7 KIY72153.1 - 7.1e-08 32.2 0.4 1.2e-07 31.5 0.4 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY72153.1 - 0.0002 21.1 0.1 0.00034 20.4 0.1 1.3 1 0 0 1 1 1 1 F-box domain F-box_5 PF18511.1 KIY72153.1 - 0.028 14.0 0.0 0.06 12.9 0.0 1.6 1 0 0 1 1 1 0 F-box Bac_export_2 PF01312.19 KIY72153.1 - 0.09 12.0 0.8 0.14 11.3 0.8 1.2 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family RRM_1 PF00076.22 KIY72154.1 - 7.7e-80 262.7 3.2 1.9e-20 72.4 0.0 4.2 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 KIY72154.1 - 1.9e-24 85.6 2.7 5.8e-24 84.1 2.6 1.9 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_7 PF16367.5 KIY72154.1 - 5.8e-05 23.1 0.2 6.2 7.0 0.0 4.7 4 2 0 4 4 4 1 RNA recognition motif OB_RNB PF08206.11 KIY72154.1 - 0.00011 21.7 0.3 4.8 6.9 0.0 3.5 3 0 0 3 3 3 2 Ribonuclease B OB domain Nup35_RRM_2 PF14605.6 KIY72154.1 - 0.0018 18.3 0.4 0.96 9.5 0.0 3.8 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KIY72154.1 - 0.018 15.0 7.1 6.1 7.0 0.2 4.1 3 1 2 5 5 5 0 RNA binding motif DUF4407 PF14362.6 KIY72154.1 - 0.026 13.9 1.8 0.035 13.5 0.8 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Nefa_Nip30_N PF10187.9 KIY72154.1 - 0.093 13.1 0.3 0.093 13.1 0.3 2.2 2 0 0 2 2 2 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 CSD PF00313.22 KIY72154.1 - 0.22 11.4 0.9 36 4.3 0.1 3.3 3 0 0 3 3 3 0 'Cold-shock' DNA-binding domain YflT PF11181.8 KIY72154.1 - 1.3 9.6 4.0 7.4 7.1 0.6 2.7 3 0 0 3 3 3 0 Heat induced stress protein YflT DUF4078 PF13300.6 KIY72154.1 - 8.8 6.7 8.9 0.5 10.7 0.8 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4078) SCAMP PF04144.13 KIY72155.1 - 1.4e-49 168.7 14.8 1.7e-49 168.5 14.8 1.0 1 0 0 1 1 1 1 SCAMP family Phage_holin_2_4 PF16082.5 KIY72155.1 - 0.043 13.5 0.6 0.043 13.5 0.6 2.2 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like DUF4200 PF13863.6 KIY72155.1 - 0.094 13.1 4.9 0.18 12.2 4.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) DUF3552 PF12072.8 KIY72155.1 - 0.16 11.4 5.5 0.34 10.3 4.9 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) Oleosin PF01277.17 KIY72155.1 - 0.32 10.7 0.1 0.32 10.7 0.1 2.6 2 1 1 3 3 3 0 Oleosin DUF1043 PF06295.12 KIY72155.1 - 1.4 8.9 5.0 37 4.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) DUF5090 PF17009.5 KIY72155.1 - 5.3 7.0 7.4 15 5.5 7.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF5090) DOR PF14839.6 KIY72158.1 - 0.03 14.3 0.1 0.042 13.8 0.1 1.2 1 0 0 1 1 1 0 DOR family DPBB_1 PF03330.18 KIY72159.1 - 0.0014 18.9 1.3 0.0014 18.9 1.3 2.0 2 1 0 2 2 2 1 Lytic transglycolase Barwin PF00967.17 KIY72159.1 - 0.051 13.4 3.8 0.089 12.7 3.1 1.8 1 1 0 1 1 1 0 Barwin family DPBB_1 PF03330.18 KIY72160.1 - 0.0005 20.3 0.4 0.0012 19.0 0.4 1.7 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 KIY72160.1 - 0.016 15.1 1.4 0.029 14.2 1.4 1.4 1 0 0 1 1 1 0 Barwin family Pex14_N PF04695.13 KIY72160.1 - 0.092 13.4 4.1 0.13 12.9 4.1 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region UCH PF00443.29 KIY72161.1 - 6.8e-53 179.8 0.9 8.9e-53 179.4 0.9 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KIY72161.1 - 2.6e-18 66.7 6.8 2.6e-18 66.7 6.8 2.5 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KIY72161.1 - 2.4e-10 40.6 8.5 2.4e-10 40.6 8.5 2.8 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein C1_1 PF00130.22 KIY72162.1 - 4.9e-09 35.9 15.7 1.1e-07 31.6 1.2 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 KIY72162.1 - 2.2e-05 24.7 15.1 0.024 14.9 0.4 2.7 2 0 0 2 2 2 2 C1 domain UNC-79 PF14776.6 KIY72162.1 - 0.018 13.8 0.0 0.033 13.0 0.0 1.4 1 0 0 1 1 1 0 Cation-channel complex subunit UNC-79 Prok-RING_1 PF14446.6 KIY72162.1 - 2.2 8.3 6.6 6.8 6.7 6.6 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Glyco_hydro_cc PF11790.8 KIY72163.1 - 4.4e-56 190.1 7.4 6e-56 189.7 7.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core tRNA_anti-codon PF01336.25 KIY72164.1 - 7.5e-05 22.6 0.0 0.00018 21.4 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF1730 PF08331.10 KIY72164.1 - 0.02 14.8 0.0 0.053 13.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1730) TnpV PF14198.6 KIY72164.1 - 0.028 14.4 0.1 0.054 13.5 0.1 1.4 1 0 0 1 1 1 0 Transposon-encoded protein TnpV PI3K_rbd PF00794.18 KIY72164.1 - 0.17 12.0 0.0 0.38 10.9 0.0 1.5 1 0 0 1 1 1 0 PI3-kinase family, ras-binding domain RPA_C PF08784.11 KIY72165.1 - 9.7e-06 26.2 0.0 4.3e-05 24.1 0.0 2.0 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 KIY72165.1 - 4.6e-05 23.3 0.0 7.6e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain MarR_2 PF12802.7 KIY72165.1 - 0.14 12.0 0.0 3.8 7.5 0.0 2.7 2 1 0 2 2 2 0 MarR family DUF2315 PF10231.9 KIY72166.1 - 4.1e-22 78.6 0.3 2.1e-21 76.2 0.3 1.8 1 1 0 1 1 1 1 Apoptogenic protein 1 ProSAAS PF07259.12 KIY72166.1 - 0.018 15.0 0.6 0.028 14.4 0.6 1.2 1 0 0 1 1 1 0 ProSAAS precursor WD40 PF00400.32 KIY72167.1 - 2.2e-30 104.2 12.1 3.3e-08 34.1 0.1 8.1 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY72167.1 - 4.2e-16 59.0 0.1 4.7e-05 23.6 0.0 5.8 2 2 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIY72167.1 - 4.4e-06 25.9 0.0 0.015 14.3 0.0 3.0 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KIY72167.1 - 0.00085 18.7 0.0 3.5 6.8 0.0 3.5 3 1 1 4 4 4 2 WD40-like domain PQQ_2 PF13360.6 KIY72167.1 - 0.0061 16.2 1.9 0.063 12.8 0.1 2.6 1 1 1 2 2 2 2 PQQ-like domain SH3_2 PF07653.17 KIY72167.1 - 0.15 11.7 0.1 1.7 8.4 0.0 2.5 2 0 0 2 2 2 0 Variant SH3 domain WDCP PF15390.6 KIY72167.1 - 0.16 10.3 0.1 0.28 9.5 0.0 1.3 2 0 0 2 2 2 0 WD repeat and coiled-coil-containing protein family PD40 PF07676.12 KIY72167.1 - 0.29 11.1 1.0 36 4.4 0.0 3.0 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Nucleoporin_C PF03177.14 KIY72168.1 - 1.3e-63 215.8 0.0 2.1e-63 215.0 0.0 1.4 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.11 KIY72168.1 - 2.3e-13 49.7 0.1 3.5e-13 49.1 0.1 1.2 1 0 0 1 1 1 1 Nup133 N terminal like DUF1132 PF06575.12 KIY72168.1 - 0.062 13.7 0.3 0.27 11.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1132) IBR PF01485.21 KIY72169.1 - 1.8e-14 53.7 26.3 2.2e-09 37.4 4.3 3.4 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain zf-RING_UBOX PF13445.6 KIY72169.1 - 7.8e-05 22.6 3.8 7.8e-05 22.6 3.8 3.5 3 1 0 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KIY72169.1 - 0.00024 20.9 4.7 0.00024 20.9 4.7 3.7 3 2 2 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KIY72169.1 - 0.00034 20.4 4.6 0.00034 20.4 4.6 3.9 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KIY72169.1 - 0.00045 20.0 1.9 0.00045 20.0 1.9 3.9 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIY72169.1 - 0.0095 16.3 4.3 0.0095 16.3 4.3 4.0 3 1 1 4 4 4 1 Ring finger domain zf-C3HC4_4 PF15227.6 KIY72169.1 - 8.7 6.6 26.3 0.057 13.6 5.0 3.8 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING RIFIN PF02009.16 KIY72171.1 - 0.0019 18.2 0.2 0.0031 17.5 0.2 1.2 1 0 0 1 1 1 1 Rifin Apt1 PF10351.9 KIY72171.1 - 5 5.9 10.9 7.5 5.3 10.9 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain SAP PF02037.27 KIY72172.1 - 1.5e-12 46.9 0.0 2.3e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 SAP domain IBR PF01485.21 KIY72173.1 - 6.1e-12 45.6 27.5 1.2e-07 31.8 3.1 3.5 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 KIY72173.1 - 0.0053 16.6 8.8 0.0053 16.6 8.8 3.5 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KIY72173.1 - 0.013 15.4 6.3 0.013 15.4 6.3 4.1 3 1 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) SLS PF14611.6 KIY72173.1 - 0.017 15.0 0.0 0.045 13.6 0.0 1.7 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator Eapp_C PF10238.9 KIY72173.1 - 0.16 12.0 5.5 0.16 12.0 2.5 2.6 2 0 0 2 2 2 0 E2F-associated phosphoprotein UPF0547 PF10571.9 KIY72173.1 - 4.4 7.5 7.6 17 5.6 0.4 3.0 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Peptidase_C14 PF00656.22 KIY72174.1 - 4.7e-23 82.4 0.0 8e-23 81.7 0.0 1.3 1 0 0 1 1 1 1 Caspase domain Peptidase_C14 PF00656.22 KIY72175.1 - 3.3e-24 86.2 0.0 5.4e-24 85.5 0.0 1.2 1 0 0 1 1 1 1 Caspase domain FlgT_C PF16538.5 KIY72175.1 - 0.034 14.7 0.0 0.1 13.1 0.0 1.8 1 0 0 1 1 1 0 Flagellar assembly protein T, C-terminal domain Peptidase_C14 PF00656.22 KIY72176.1 - 4.8e-23 82.4 0.0 8.3e-23 81.6 0.0 1.3 1 0 0 1 1 1 1 Caspase domain Peptidase_C14 PF00656.22 KIY72177.1 - 1.6e-17 64.3 0.0 4.1e-17 63.0 0.0 1.6 2 0 0 2 2 2 1 Caspase domain WD40 PF00400.32 KIY72178.1 - 1.4e-05 25.7 9.8 0.28 12.1 0.1 5.1 5 1 0 5 5 5 3 WD domain, G-beta repeat RNase_H PF00075.24 KIY72179.1 - 2.4e-15 57.0 0.0 3.8e-15 56.3 0.0 1.2 1 0 0 1 1 1 1 RNase H Swi3 PF07962.12 KIY72180.1 - 3e-24 84.8 0.4 4.7e-24 84.2 0.4 1.3 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 Methyltransf_PK PF05891.12 KIY72181.1 - 1.1e-51 175.4 0.0 2.7e-51 174.2 0.0 1.6 1 1 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 KIY72181.1 - 6.2e-07 30.0 0.0 0.019 15.6 0.0 2.4 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 KIY72181.1 - 0.00015 21.7 0.0 0.00022 21.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIY72181.1 - 0.00019 22.0 0.0 0.0088 16.7 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIY72181.1 - 0.00034 21.3 0.0 0.0017 19.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KIY72181.1 - 0.17 11.4 0.0 0.47 10.0 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain ADK PF00406.22 KIY72182.1 - 2.4e-44 151.1 0.0 4.9e-44 150.1 0.0 1.4 2 0 0 2 2 2 1 Adenylate kinase AAA_17 PF13207.6 KIY72182.1 - 2.6e-18 66.7 0.0 6.1e-18 65.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain ADK_lid PF05191.14 KIY72182.1 - 9.9e-13 47.8 0.0 2.2e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 KIY72182.1 - 6.3e-08 33.2 0.0 1.2e-07 32.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KIY72182.1 - 0.00045 20.4 0.0 0.001 19.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain Hydin_ADK PF17213.3 KIY72182.1 - 0.014 15.7 0.0 0.026 14.8 0.0 1.4 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Ploopntkinase3 PF18751.1 KIY72182.1 - 0.029 14.3 0.0 0.047 13.6 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 Epimerase PF01370.21 KIY72183.1 - 1.4e-08 34.5 0.0 2.6e-06 27.1 0.0 2.4 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KIY72183.1 - 5.1e-06 26.5 0.0 1.7e-05 24.8 0.0 1.9 1 1 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KIY72183.1 - 0.0032 16.5 0.0 0.013 14.5 0.0 1.8 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KIY72183.1 - 0.018 14.5 0.0 0.025 14.0 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase adh_short PF00106.25 KIY72183.1 - 0.058 12.8 0.0 0.08 12.4 0.0 1.2 1 0 0 1 1 1 0 short chain dehydrogenase RmlD_sub_bind PF04321.17 KIY72183.1 - 0.077 12.1 0.0 0.23 10.5 0.0 1.7 2 0 0 2 2 2 0 RmlD substrate binding domain NmrA PF05368.13 KIY72183.1 - 0.19 11.2 0.2 0.46 10.0 0.2 1.8 1 1 0 1 1 1 0 NmrA-like family SH2_2 PF14633.6 KIY72184.1 - 6.3e-70 235.0 1.1 1.1e-69 234.1 1.1 1.4 1 0 0 1 1 1 1 SH2 domain HHH_7 PF14635.6 KIY72184.1 - 2.3e-25 88.9 0.0 5.5e-25 87.7 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.6 KIY72184.1 - 2.8e-23 82.4 0.0 6.3e-23 81.2 0.0 1.7 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HTH_44 PF14641.6 KIY72184.1 - 5.1e-22 78.5 0.3 1.7e-21 76.8 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix DNA-binding domain of SPT6 SH2 PF00017.24 KIY72184.1 - 3.6e-08 33.4 0.0 1.9e-05 24.7 0.0 3.2 3 0 0 3 3 3 1 SH2 domain HHH_9 PF17674.1 KIY72184.1 - 1.1e-05 26.3 0.6 9.5e-05 23.2 0.6 2.7 1 1 0 1 1 1 1 HHH domain HHH_3 PF12836.7 KIY72184.1 - 0.0001 22.5 0.1 0.0015 18.7 0.0 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix motif Tex_N PF09371.10 KIY72184.1 - 0.00014 21.6 0.2 0.01 15.5 0.0 2.5 2 0 0 2 2 2 1 Tex-like protein N-terminal domain DUF3848 PF12959.7 KIY72184.1 - 0.056 13.5 0.9 0.22 11.6 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3848) DUF4609 PF15382.6 KIY72184.1 - 0.1 12.5 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4609) K_oxygenase PF13434.6 KIY72185.1 - 5.8e-88 295.3 0.0 7.1e-88 295.0 0.0 1.1 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KIY72185.1 - 1.5e-06 27.7 0.0 3.6e-06 26.4 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIY72185.1 - 2.4e-06 28.0 0.0 0.12 12.9 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KIY72185.1 - 6e-05 22.4 0.0 0.0072 15.6 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KIY72185.1 - 7.5e-05 22.8 0.0 0.018 15.1 0.0 2.7 2 1 0 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.24 KIY72185.1 - 0.013 15.1 0.0 0.21 11.1 0.0 2.3 2 1 1 3 3 3 0 FAD dependent oxidoreductase DAGK_cat PF00781.24 KIY72186.1 - 7.9e-25 86.9 0.0 1.5e-24 86.0 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Methyltransf_11 PF08241.12 KIY72187.1 - 1.2e-14 54.8 0.0 1.2e-13 51.5 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIY72187.1 - 5.2e-11 43.1 0.0 5.1e-10 39.9 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIY72187.1 - 2.1e-07 31.6 0.0 3.9e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIY72187.1 - 2.6e-05 24.1 0.0 5.1e-05 23.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIY72187.1 - 0.0008 18.8 0.0 0.0016 17.8 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_28 PF02636.17 KIY72187.1 - 0.003 17.2 0.0 0.0056 16.4 0.0 1.5 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_31 PF13847.6 KIY72187.1 - 0.035 13.9 0.0 1.1 9.0 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Unstab_antitox PF09720.10 KIY72187.1 - 0.097 12.7 0.1 0.22 11.6 0.1 1.6 1 0 0 1 1 1 0 Putative addiction module component Methyltransf_16 PF10294.9 KIY72187.1 - 0.15 11.8 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 Lysine methyltransferase RrnaAD PF00398.20 KIY72187.1 - 0.23 10.5 0.0 0.37 9.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase NatB_MDM20 PF09797.9 KIY72188.1 - 6.5e-71 239.3 0.6 1.1e-70 238.6 0.6 1.3 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_19 PF14559.6 KIY72188.1 - 2.7e-11 43.8 1.1 0.0003 21.2 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KIY72188.1 - 5.4e-08 33.0 2.7 0.17 12.8 0.0 5.9 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_15 PF13429.6 KIY72188.1 - 0.00013 21.3 1.0 0.016 14.5 0.1 2.7 2 1 0 2 2 2 2 Tetratricopeptide repeat BTAD PF03704.17 KIY72188.1 - 0.00027 21.4 5.3 0.02 15.3 0.2 4.0 3 1 0 4 4 4 1 Bacterial transcriptional activator domain TPR_1 PF00515.28 KIY72188.1 - 0.00066 19.4 0.0 8.2 6.4 0.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KIY72188.1 - 0.0069 16.3 0.2 0.92 9.7 0.0 4.2 4 1 0 4 4 4 1 Tetratricopeptide repeat rve_3 PF13683.6 KIY72188.1 - 0.068 13.0 0.2 0.2 11.5 0.2 1.8 1 0 0 1 1 1 0 Integrase core domain TPR_10 PF13374.6 KIY72188.1 - 0.2 11.6 2.7 1.7 8.7 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 KIY72188.1 - 5.4 7.4 6.4 7.2 7.0 0.1 3.9 4 1 1 5 5 5 0 Tetratricopeptide repeat ATG_C PF09333.11 KIY72189.1 - 8.4e-36 122.2 0.7 2.8e-35 120.6 0.1 2.3 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain Chorein_N PF12624.7 KIY72189.1 - 1.8e-12 47.4 0.0 6.9e-12 45.5 0.0 2.0 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 ATG2_CAD PF13329.6 KIY72189.1 - 2.9e-10 40.1 0.1 7.8e-09 35.4 0.0 3.2 3 1 1 4 4 4 1 Autophagy-related protein 2 CAD motif VPS13_C PF16909.5 KIY72189.1 - 0.00087 19.1 0.1 0.0036 17.1 0.0 1.9 2 0 0 2 2 2 1 Vacuolar-sorting-associated 13 protein C-terminal Ribosomal_L24e PF01246.20 KIY72190.1 - 1.1e-31 108.9 6.1 1.1e-31 108.9 6.1 2.0 2 0 0 2 2 2 1 Ribosomal protein L24e zf-FCS PF06467.14 KIY72190.1 - 0.1 12.5 4.1 0.18 11.8 4.1 1.4 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif Vps55 PF04133.14 KIY72191.1 - 9.3e-43 144.9 6.9 1e-42 144.7 6.9 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 Herpes_LMP1 PF05297.11 KIY72191.1 - 0.03 13.5 0.4 0.04 13.1 0.4 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DUF2933 PF11666.8 KIY72191.1 - 0.48 10.5 5.5 0.12 12.4 1.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2933) Glyco_hydro_3_C PF01915.22 KIY72192.1 - 7.5e-54 182.8 0.0 1.5e-53 181.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KIY72192.1 - 8.8e-42 143.6 0.0 1.5e-41 142.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KIY72192.1 - 4.7e-18 65.1 0.0 9.5e-18 64.1 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain INCENP_ARK-bind PF03941.15 KIY72192.1 - 0.2 11.6 0.9 2.1 8.4 0.0 2.4 1 1 1 2 2 2 0 Inner centromere protein, ARK binding region Lipase_GDSL_2 PF13472.6 KIY72193.1 - 2.9e-05 24.6 0.0 3.9e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KIY72193.1 - 8e-05 22.7 0.0 0.00013 22.0 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase SRP54 PF00448.22 KIY72194.1 - 1.6e-72 243.3 1.4 2.8e-72 242.5 1.4 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 KIY72194.1 - 6.2e-31 107.0 1.4 6.2e-31 107.0 1.4 4.4 4 0 0 4 4 4 1 Signal peptide binding domain SRP54_N PF02881.19 KIY72194.1 - 7.5e-19 67.7 4.3 1.8e-18 66.5 4.3 1.7 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_17 PF13207.6 KIY72194.1 - 0.00035 21.0 0.9 0.00089 19.7 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KIY72194.1 - 0.00042 20.5 0.1 0.0009 19.4 0.1 1.5 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 KIY72194.1 - 0.0022 17.1 0.7 0.0042 16.1 0.3 1.7 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB CbiA PF01656.23 KIY72194.1 - 0.0061 16.6 0.0 0.019 15.0 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_30 PF13604.6 KIY72194.1 - 0.015 15.0 0.9 0.036 13.8 0.2 2.0 2 0 0 2 2 2 0 AAA domain Med10 PF09748.9 KIY72194.1 - 0.024 14.6 0.2 1.7 8.6 0.1 2.5 2 0 0 2 2 2 0 Transcription factor subunit Med10 of Mediator complex AAA_22 PF13401.6 KIY72194.1 - 0.03 14.6 0.1 0.13 12.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 KIY72194.1 - 0.03 13.2 0.3 0.34 9.8 0.0 2.6 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain Zeta_toxin PF06414.12 KIY72194.1 - 0.037 13.3 0.2 0.073 12.3 0.2 1.5 1 0 0 1 1 1 0 Zeta toxin ATP_bind_1 PF03029.17 KIY72194.1 - 0.069 12.9 0.1 0.22 11.3 0.1 1.8 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein SRPRB PF09439.10 KIY72194.1 - 0.1 12.1 1.7 7.3 6.0 0.1 2.9 1 1 2 3 3 3 0 Signal recognition particle receptor beta subunit ESX-1_EspG PF14011.6 KIY72194.1 - 0.37 10.4 1.3 12 5.4 0.1 2.6 3 0 0 3 3 3 0 EspG family Metal_resist PF13801.6 KIY72194.1 - 6.5 7.0 7.9 1.7 8.9 3.4 2.4 2 0 0 2 2 2 0 Heavy-metal resistance WD40 PF00400.32 KIY72195.1 - 1.4e-08 35.2 11.2 3.4 8.7 0.1 7.6 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY72195.1 - 0.013 15.8 0.0 3.1 8.1 0.0 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain CDC45 PF02724.14 KIY72195.1 - 0.2 9.9 4.5 0.28 9.4 4.5 1.1 1 0 0 1 1 1 0 CDC45-like protein AF-4 PF05110.13 KIY72195.1 - 2.7 6.0 5.1 3.7 5.5 5.1 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Methyltransf_23 PF13489.6 KIY72196.1 - 2e-18 66.8 0.0 2.9e-18 66.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIY72196.1 - 6.5e-14 52.4 0.0 1.2e-13 51.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIY72196.1 - 1.4e-12 48.2 0.0 3.1e-12 47.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIY72196.1 - 6.8e-12 45.4 0.0 1.4e-10 41.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIY72196.1 - 1.1e-06 29.3 0.0 3.4e-06 27.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.16 KIY72196.1 - 0.0001 21.0 0.0 0.0002 20.1 0.0 1.4 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Ubie_methyltran PF01209.18 KIY72196.1 - 0.0022 17.4 0.0 0.016 14.6 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 KIY72196.1 - 0.0041 16.6 0.0 0.16 11.5 0.0 2.2 2 0 0 2 2 2 1 Putative methyltransferase FtsJ PF01728.19 KIY72196.1 - 0.0045 17.1 0.0 0.0078 16.3 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase PrmA PF06325.13 KIY72196.1 - 0.027 13.9 0.0 0.044 13.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KIY72196.1 - 0.029 13.9 0.0 0.098 12.2 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain PCMT PF01135.19 KIY72196.1 - 0.15 11.8 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_2 PF00891.18 KIY72196.1 - 0.2 10.9 0.0 0.5 9.6 0.0 1.6 1 1 0 1 1 1 0 O-methyltransferase domain Methyltransf_8 PF05148.15 KIY72196.1 - 0.24 11.2 0.0 0.39 10.5 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase PAC3 PF10178.9 KIY72198.1 - 0.00063 19.8 0.6 0.0022 18.1 0.6 1.9 1 1 0 1 1 1 1 Proteasome assembly chaperone 3 NCE101 PF11654.8 KIY72199.1 - 4.5e-19 67.9 0.1 5.4e-19 67.6 0.1 1.1 1 0 0 1 1 1 1 Non-classical export protein 1 DUF5353 PF17304.2 KIY72200.1 - 4.5 7.1 5.9 32 4.3 5.9 2.1 1 1 0 1 1 1 0 Family of unknown function (DUF5353) RhoGEF PF00621.20 KIY72201.1 - 3.7e-35 121.8 0.0 1.1e-34 120.3 0.0 1.8 2 0 0 2 2 2 1 RhoGEF domain BAR PF03114.18 KIY72201.1 - 0.012 15.2 0.0 0.026 14.1 0.0 1.6 1 0 0 1 1 1 0 BAR domain ARL6IP6 PF15062.6 KIY72201.1 - 0.019 15.1 0.9 0.11 12.7 0.9 2.3 1 0 0 1 1 1 0 Haemopoietic lineage transmembrane helix DUF629 PF04780.12 KIY72202.1 - 0.24 9.9 0.5 0.32 9.5 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF629) Med16 PF11635.8 KIY72204.1 - 1.6e-06 26.4 0.1 2.3e-05 22.6 0.1 2.1 2 0 0 2 2 2 2 Mediator complex subunit 16 Condensation PF00668.20 KIY72205.1 - 0.00013 20.8 0.0 0.00019 20.2 0.0 1.1 1 0 0 1 1 1 1 Condensation domain SHOCT PF09851.9 KIY72205.1 - 0.0008 19.1 0.3 0.0016 18.1 0.3 1.5 1 0 0 1 1 1 1 Short C-terminal domain AA_permease_2 PF13520.6 KIY72206.1 - 7.8e-75 252.3 29.6 1e-74 251.9 29.6 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KIY72206.1 - 3.7e-17 62.1 23.1 5.2e-17 61.6 23.1 1.1 1 0 0 1 1 1 1 Amino acid permease TruB_N PF01509.18 KIY72207.1 - 8.9e-46 155.9 0.0 3.7e-45 153.9 0.0 1.9 1 1 1 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 KIY72207.1 - 0.00026 21.1 0.0 0.00054 20.1 0.0 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain DHDPS PF00701.22 KIY72208.1 - 9.4e-30 103.3 0.0 4e-29 101.2 0.0 1.7 1 1 0 1 1 1 1 Dihydrodipicolinate synthetase family Ribosomal_L34e PF01199.18 KIY72209.1 - 2.2e-42 143.3 2.0 2.7e-42 143.0 2.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L34e PNTB PF02233.16 KIY72210.1 - 6.8e-157 523.1 31.3 6.8e-157 523.1 31.3 2.1 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 KIY72210.1 - 7.6e-76 254.1 0.4 3.6e-75 252.0 0.7 2.1 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 KIY72210.1 - 5e-39 133.7 0.0 1.2e-38 132.5 0.0 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 KIY72210.1 - 5e-32 110.2 4.4 5e-32 110.2 4.4 4.7 2 1 1 3 3 3 1 4TM region of pyridine nucleotide transhydrogenase, mitoch 2-Hacid_dh_C PF02826.19 KIY72210.1 - 6.6e-05 22.3 1.0 0.22 10.9 0.1 4.0 4 0 0 4 4 4 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TPP_enzyme_M PF00205.22 KIY72210.1 - 0.0024 17.6 0.2 0.013 15.2 0.2 2.3 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain Pyr_redox_2 PF07992.14 KIY72210.1 - 0.014 14.6 0.4 0.028 13.6 0.4 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KIY72210.1 - 0.033 13.3 0.6 0.058 12.5 0.6 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_8 PF13450.6 KIY72210.1 - 0.13 12.5 8.0 1.7 8.9 0.5 3.7 4 0 0 4 4 4 0 NAD(P)-binding Rossmann-like domain IMPDH PF00478.25 KIY72211.1 - 9.1e-131 435.9 0.2 3e-130 434.2 0.2 1.7 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 KIY72211.1 - 2.1e-16 60.1 0.5 2.2e-07 31.2 0.0 2.9 3 0 0 3 3 3 2 CBS domain FMN_dh PF01070.18 KIY72211.1 - 9.1e-11 41.4 1.5 1.9e-10 40.3 1.5 1.5 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.15 KIY72211.1 - 3.7e-05 23.3 12.4 0.0092 15.4 9.9 2.9 2 1 0 2 2 2 2 Nitronate monooxygenase ThiG PF05690.14 KIY72211.1 - 0.00012 21.5 0.7 0.00028 20.3 0.7 1.6 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 KIY72211.1 - 0.00022 20.8 4.3 0.00083 18.9 1.1 2.4 1 1 1 2 2 2 1 Histidine biosynthesis protein Dus PF01207.17 KIY72211.1 - 0.21 10.6 0.7 2.4 7.2 0.0 2.1 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) G3P_antiterm PF04309.12 KIY72211.1 - 0.22 10.9 1.6 2.7 7.4 0.2 2.3 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator Glu_synthase PF01645.17 KIY72211.1 - 0.3 10.2 3.8 0.48 9.5 3.8 1.3 1 0 0 1 1 1 0 Conserved region in glutamate synthase TMP-TENI PF02581.17 KIY72211.1 - 4 6.7 6.3 6.3 6.1 0.1 2.7 3 0 0 3 3 3 0 Thiamine monophosphate synthase Tim17 PF02466.19 KIY72212.1 - 4.4e-27 94.7 9.6 5.6e-27 94.3 9.6 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family MFS_1 PF07690.16 KIY72213.1 - 6.5e-37 127.3 32.1 6.5e-37 127.3 32.1 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIY72213.1 - 1.1e-14 54.1 10.4 1.1e-14 54.1 10.4 2.7 3 1 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 KIY72213.1 - 2.6e-07 29.5 4.0 4.2e-07 28.8 4.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 KIY72213.1 - 0.007 14.8 4.8 0.011 14.1 4.8 1.3 1 0 0 1 1 1 1 Transmembrane secretion effector p450 PF00067.22 KIY72214.1 - 8.8e-66 222.5 0.0 6.3e-64 216.4 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 Nop53 PF07767.11 KIY72215.1 - 9.9e-93 311.7 20.3 1.2e-92 311.4 20.3 1.0 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) FAD_binding_3 PF01494.19 KIY72216.1 - 2.8e-42 145.2 0.6 2.9e-41 141.9 0.6 2.0 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KIY72216.1 - 1e-07 31.5 0.0 1.1e-06 28.2 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIY72216.1 - 4.5e-07 29.8 0.8 2.1e-06 27.6 0.1 1.9 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIY72216.1 - 1e-06 28.2 0.3 0.0024 17.1 0.1 2.3 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KIY72216.1 - 5.8e-06 25.6 0.2 8.1e-05 21.8 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox PF00070.27 KIY72216.1 - 1.7e-05 25.3 0.0 0.005 17.4 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIY72216.1 - 0.00022 21.4 0.1 0.00049 20.3 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain ThiF PF00899.21 KIY72216.1 - 0.0014 18.0 0.0 0.0026 17.1 0.0 1.3 1 0 0 1 1 1 1 ThiF family TrkA_N PF02254.18 KIY72216.1 - 0.0015 18.8 0.0 0.003 17.8 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_9 PF13454.6 KIY72216.1 - 0.0015 18.5 0.4 0.38 10.7 0.0 2.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KIY72216.1 - 0.002 17.3 1.1 0.0029 16.7 0.5 1.6 2 0 0 2 2 2 1 FAD binding domain Shikimate_DH PF01488.20 KIY72216.1 - 0.0055 16.8 0.0 0.011 15.8 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Glu_dehyd_C PF16912.5 KIY72216.1 - 0.0059 16.1 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus UDPG_MGDP_dh_N PF03721.14 KIY72216.1 - 0.013 15.1 0.1 0.029 13.9 0.0 1.7 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain SE PF08491.10 KIY72216.1 - 0.017 14.2 0.0 0.028 13.5 0.0 1.4 1 0 0 1 1 1 0 Squalene epoxidase HI0933_like PF03486.14 KIY72216.1 - 0.017 13.8 0.1 0.83 8.3 0.1 2.2 2 0 0 2 2 2 0 HI0933-like protein Ldh_1_N PF00056.23 KIY72216.1 - 0.02 15.0 0.0 0.039 14.0 0.0 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KIY72216.1 - 0.023 14.9 0.4 0.066 13.5 0.0 1.9 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Thi4 PF01946.17 KIY72216.1 - 0.049 12.9 0.0 0.094 11.9 0.0 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_7 PF13241.6 KIY72216.1 - 0.05 14.0 0.0 0.13 12.7 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding F420_oxidored PF03807.17 KIY72216.1 - 0.058 14.0 0.0 0.17 12.4 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 KIY72216.1 - 0.061 13.0 0.1 0.13 11.9 0.1 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA K_oxygenase PF13434.6 KIY72216.1 - 0.13 11.4 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Chromo PF00385.24 KIY72218.1 - 0.00017 21.4 0.2 0.0003 20.6 0.2 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Filo_glycop PF01611.16 KIY72218.1 - 0.26 10.2 5.3 0.44 9.4 5.3 1.3 1 0 0 1 1 1 0 Filovirus glycoprotein Pneumo_att_G PF05539.11 KIY72218.1 - 0.44 10.1 5.7 0.79 9.3 5.7 1.4 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G PQ-loop PF04193.14 KIY72219.1 - 9.9e-36 121.3 9.5 2.3e-17 62.5 3.9 2.5 2 0 0 2 2 2 2 PQ loop repeat DUF417 PF04224.12 KIY72219.1 - 0.0079 15.8 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF417 MtN3_slv PF03083.16 KIY72219.1 - 0.1 12.7 0.5 0.1 12.7 0.5 1.8 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange AA_permease_C PF13906.6 KIY72219.1 - 0.43 10.7 2.9 3 8.0 0.4 2.7 2 0 0 2 2 2 0 C-terminus of AA_permease CAMSAP_CC1 PF17095.5 KIY72220.1 - 0.0078 16.0 0.1 0.014 15.2 0.1 1.3 1 0 0 1 1 1 1 Spectrin-binding region of Ca2+-Calmodulin DUF4106 PF13388.6 KIY72225.1 - 4.9 6.3 4.9 6.2 6.0 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) TMPIT PF07851.13 KIY72226.1 - 0.16 11.2 1.1 0.31 10.2 1.1 1.4 1 0 0 1 1 1 0 TMPIT-like protein Cep57_CLD_2 PF14197.6 KIY72226.1 - 0.26 11.4 9.2 0.036 14.1 4.8 1.9 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Prothymosin PF03247.14 KIY72226.1 - 3.6 8.1 17.2 0.15 12.6 7.7 2.7 2 0 0 2 2 2 0 Prothymosin/parathymosin family Peptidase_S64 PF08192.11 KIY72226.1 - 5.6 5.3 22.5 8.1 4.8 22.5 1.2 1 0 0 1 1 1 0 Peptidase family S64 GYF PF02213.16 KIY72227.1 - 0.0018 17.9 0.7 0.01 15.5 0.1 2.2 2 0 0 2 2 2 1 GYF domain Oxysterol_BP PF01237.18 KIY72227.1 - 0.038 12.8 10.1 0.055 12.3 10.1 1.2 1 0 0 1 1 1 0 Oxysterol-binding protein Nuc_sug_transp PF04142.15 KIY72228.1 - 6.4e-91 304.8 5.3 3.6e-82 276.0 5.5 2.1 2 0 0 2 2 2 2 Nucleotide-sugar transporter EamA PF00892.20 KIY72228.1 - 0.00037 20.7 23.6 0.0011 19.1 2.2 3.8 3 1 0 3 3 3 1 EamA-like transporter family UAA PF08449.11 KIY72228.1 - 0.01 15.1 6.6 0.018 14.2 6.6 1.3 1 0 0 1 1 1 0 UAA transporter family TPT PF03151.16 KIY72228.1 - 0.17 11.2 6.5 1.2 8.4 0.6 2.2 2 0 0 2 2 2 0 Triose-phosphate Transporter family DUF202 PF02656.15 KIY72228.1 - 6.4 7.3 9.0 0.2 12.1 0.5 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF202) DUF4231 PF14015.6 KIY72228.1 - 7.7 7.0 8.0 2 8.9 1.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) AJAP1_PANP_C PF15298.6 KIY72229.1 - 0.012 15.8 3.1 0.035 14.3 3.1 1.7 1 0 0 1 1 1 0 AJAP1/PANP C-terminus DUF4818 PF16089.5 KIY72229.1 - 0.027 14.9 0.0 0.048 14.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4818) SSP160 PF06933.11 KIY72229.1 - 1.9 6.6 18.6 3.4 5.7 18.6 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Lactonase PF10282.9 KIY72230.1 - 4.6e-39 134.6 0.0 5.6e-39 134.4 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Abhydrolase_6 PF12697.7 KIY72231.1 - 6.9e-08 33.4 1.7 1.2e-07 32.6 1.7 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIY72231.1 - 0.047 12.9 0.0 0.072 12.4 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KIY72231.1 - 0.052 13.2 0.1 0.082 12.5 0.1 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold HypA PF01155.19 KIY72231.1 - 0.079 13.0 0.5 0.12 12.4 0.5 1.3 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TauE PF01925.19 KIY72232.1 - 0.41 10.3 4.5 1.3 8.6 4.5 1.7 1 1 0 1 1 1 0 Sulfite exporter TauE/SafE Rcd1 PF04078.13 KIY72233.1 - 2.1e-125 417.2 2.7 2.4e-125 417.1 2.7 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like EMP24_GP25L PF01105.24 KIY72234.1 - 2.3e-49 167.8 0.3 2.6e-49 167.6 0.3 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD HR1 PF02185.16 KIY72234.1 - 0.02 15.0 1.4 0.032 14.3 1.4 1.3 1 0 0 1 1 1 0 Hr1 repeat PAP_RNA-bind PF04926.15 KIY72234.1 - 0.022 14.4 0.1 0.035 13.7 0.1 1.4 1 0 0 1 1 1 0 Poly(A) polymerase predicted RNA binding domain BST2 PF16716.5 KIY72234.1 - 0.08 13.5 0.0 0.13 12.8 0.0 1.3 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 60KD_IMP PF02096.20 KIY72234.1 - 0.094 12.6 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 60Kd inner membrane protein IL1 PF00340.19 KIY72234.1 - 0.15 11.8 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Interleukin-1 / 18 Thioredoxin PF00085.20 KIY72237.1 - 2.7e-27 94.7 0.1 3.2e-27 94.5 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KIY72237.1 - 1.7e-07 31.7 0.1 5.6e-07 30.0 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 KIY72237.1 - 3.1e-07 30.2 0.1 3.9e-07 29.9 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 KIY72237.1 - 0.00019 20.9 0.0 0.0002 20.8 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 KIY72237.1 - 0.0002 21.3 0.0 0.00023 21.1 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 KIY72237.1 - 0.00059 20.1 0.0 0.0083 16.4 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_7 PF13899.6 KIY72237.1 - 0.0034 17.5 0.0 0.004 17.3 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 KIY72237.1 - 0.0051 16.5 0.0 0.0058 16.3 0.0 1.2 1 0 0 1 1 1 1 Redoxin CRAL_TRIO PF00650.20 KIY72238.1 - 7e-39 133.1 0.0 9.1e-39 132.7 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KIY72238.1 - 2.9e-05 24.1 0.9 5.4e-05 23.3 0.9 1.4 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KIY72238.1 - 0.012 15.8 0.0 0.019 15.1 0.0 1.3 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain DUF563 PF04577.14 KIY72239.1 - 1.6e-25 90.5 0.0 2.3e-25 90.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) MFS_1 PF07690.16 KIY72240.1 - 1.9e-34 119.1 65.9 1.4e-30 106.5 34.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Lactonase PF10282.9 KIY72241.1 - 5e-33 114.8 0.0 6.3e-33 114.5 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Pkinase PF00069.25 KIY72243.1 - 1.6e-63 214.5 0.0 3.7e-63 213.4 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY72243.1 - 9.2e-44 149.7 0.0 1.9e-43 148.6 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3543 PF12063.8 KIY72243.1 - 1e-36 126.6 0.6 2.7e-36 125.2 0.6 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3543) APH PF01636.23 KIY72243.1 - 0.0012 18.8 0.3 0.068 13.1 0.1 2.9 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KIY72243.1 - 0.021 13.6 0.0 0.052 12.3 0.0 1.6 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 KIY72243.1 - 0.086 12.2 0.2 0.35 10.2 0.0 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Glyco_transf_15 PF01793.16 KIY72245.1 - 7.8e-113 377.0 5.4 9.4e-113 376.7 5.4 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Tropomyosin_1 PF12718.7 KIY72246.1 - 0.019 15.1 4.9 0.019 15.1 4.9 4.1 2 1 2 4 4 4 0 Tropomyosin like DUF1633 PF07794.11 KIY72246.1 - 0.043 12.0 3.8 0.067 11.4 3.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1633) DUF3450 PF11932.8 KIY72246.1 - 0.043 13.1 22.1 0.047 13.0 2.5 3.5 1 1 1 3 3 3 0 Protein of unknown function (DUF3450) HALZ PF02183.18 KIY72246.1 - 0.045 14.0 1.4 0.045 14.0 1.4 3.7 4 1 1 5 5 4 0 Homeobox associated leucine zipper TPR_MLP1_2 PF07926.12 KIY72246.1 - 0.1 12.7 26.9 0.16 12.0 3.8 3.9 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein DUF4618 PF15397.6 KIY72246.1 - 0.15 11.4 20.1 0.26 10.7 20.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) FlaC_arch PF05377.11 KIY72246.1 - 0.35 11.3 6.8 47 4.5 0.1 4.5 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) Troponin PF00992.20 KIY72246.1 - 1.3 9.3 20.5 0.14 12.5 1.9 3.4 2 1 1 3 3 3 0 Troponin Nup188_C PF18378.1 KIY72246.1 - 1.5 7.6 7.4 2.5 6.8 7.4 1.3 1 0 0 1 1 1 0 Nuclear pore protein NUP188 C-terminal domain Snapin_Pallidin PF14712.6 KIY72246.1 - 1.8 9.0 15.3 0.69 10.4 2.2 3.8 4 1 0 4 4 3 0 Snapin/Pallidin Golgin_A5 PF09787.9 KIY72246.1 - 1.9 7.8 25.7 0.63 9.5 13.7 2.5 1 1 1 2 2 2 0 Golgin subfamily A member 5 MbeD_MobD PF04899.12 KIY72246.1 - 2 8.6 11.0 3.5 7.8 0.3 4.3 3 1 1 4 4 4 0 MbeD/MobD like CLZ PF16526.5 KIY72246.1 - 3.3 8.1 21.9 0.062 13.7 3.7 3.7 4 0 0 4 4 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Baculo_PEP_C PF04513.12 KIY72246.1 - 4.2 7.4 6.0 22 5.1 0.0 3.0 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4407 PF14362.6 KIY72246.1 - 6.4 6.0 19.1 4 6.7 10.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) TMF_TATA_bd PF12325.8 KIY72246.1 - 6.6 7.0 29.6 17 5.6 4.8 4.3 1 1 2 4 4 4 0 TATA element modulatory factor 1 TATA binding Rab5-bind PF09311.11 KIY72246.1 - 6.9 6.0 26.5 21 4.4 26.5 1.7 1 1 0 1 1 1 0 Rabaptin-like protein Dioxygenase_C PF00775.21 KIY72247.1 - 1.8e-08 34.0 0.3 6.8e-06 25.6 0.0 2.3 1 1 1 2 2 2 2 Dioxygenase Pyr_redox PF00070.27 KIY72248.1 - 0.0056 17.2 0.0 0.011 16.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KIY72248.1 - 0.014 14.6 0.0 0.024 13.9 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KIY72248.1 - 0.081 12.3 0.2 0.72 9.1 0.1 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase zf-4CXXC_R1 PF10497.9 KIY72250.1 - 6.9e-11 42.3 11.1 1.4e-10 41.2 11.1 1.4 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 AT_hook PF02178.19 KIY72250.1 - 9e-05 21.9 31.5 0.058 13.3 2.8 4.0 3 0 0 3 3 3 3 AT hook motif RFX5_DNA_bdg PF14621.6 KIY72250.1 - 0.02 14.7 24.2 0.068 12.9 1.5 4.2 2 1 2 4 4 4 0 RFX5 DNA-binding domain MFS_1 PF07690.16 KIY72252.1 - 5.4e-40 137.4 29.7 5.4e-40 137.4 29.7 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIY72252.1 - 2.9e-12 46.2 1.8 2.9e-12 46.2 1.8 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter MAP65_ASE1 PF03999.12 KIY72254.1 - 2.3e-65 221.5 3.2 1.3e-62 212.4 0.1 2.6 2 1 1 3 3 3 2 Microtubule associated protein (MAP65/ASE1 family) SAM_KSR1 PF13543.6 KIY72254.1 - 0.047 13.8 0.1 9.3 6.4 0.0 2.7 2 0 0 2 2 2 0 SAM like domain present in kinase suppressor RAS 1 UBN_AB PF14075.6 KIY72254.1 - 0.081 12.6 0.1 0.081 12.6 0.1 2.2 2 1 0 2 2 2 0 Ubinuclein conserved middle domain Exonuc_VII_L PF02601.15 KIY72254.1 - 0.91 9.0 7.2 2.7 7.5 0.9 2.3 2 0 0 2 2 2 0 Exonuclease VII, large subunit Kelch_4 PF13418.6 KIY72256.1 - 0.11 12.5 0.2 0.19 11.7 0.2 1.4 1 0 0 1 1 1 0 Galactose oxidase, central domain Rep_fac_C PF08542.11 KIY72257.1 - 1e-21 77.1 0.1 5.7e-21 74.7 0.0 2.3 3 0 0 3 3 2 1 Replication factor C C-terminal domain AAA PF00004.29 KIY72257.1 - 1.4e-17 64.4 0.0 2.5e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 KIY72257.1 - 8.5e-15 54.9 0.0 8.6e-11 41.9 0.1 2.3 1 1 1 2 2 2 2 DNA polymerase III, delta subunit Rad17 PF03215.15 KIY72257.1 - 3.6e-08 33.6 0.0 1.4e-07 31.6 0.0 1.9 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_30 PF13604.6 KIY72257.1 - 1.6e-06 27.9 0.0 1.4e-05 25.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 KIY72257.1 - 2.8e-06 26.7 0.0 4e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) DNA_pol3_delta PF06144.13 KIY72257.1 - 7.6e-06 25.8 0.1 1.4e-05 24.9 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_11 PF13086.6 KIY72257.1 - 1.2e-05 25.3 0.0 4e-05 23.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KIY72257.1 - 2e-05 24.6 0.2 0.00011 22.3 0.1 2.1 1 1 1 2 2 2 1 AAA domain AAA_assoc_2 PF16193.5 KIY72257.1 - 2.3e-05 24.6 0.0 7.7e-05 23.0 0.0 1.9 1 0 0 1 1 1 1 AAA C-terminal domain AAA_16 PF13191.6 KIY72257.1 - 3.7e-05 24.2 0.0 8.9e-05 22.9 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 KIY72257.1 - 0.00014 21.6 0.0 0.00031 20.5 0.0 1.6 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_19 PF13245.6 KIY72257.1 - 0.00021 21.6 0.6 0.049 14.0 0.0 2.6 2 1 1 3 3 2 1 AAA domain ResIII PF04851.15 KIY72257.1 - 0.00047 20.2 0.0 0.05 13.6 0.0 2.3 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KIY72257.1 - 0.00054 19.8 0.3 0.0028 17.4 0.5 2.0 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KIY72257.1 - 0.00087 19.6 1.1 0.46 10.7 1.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KIY72257.1 - 0.001 18.9 0.0 0.0023 17.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KIY72257.1 - 0.0017 18.3 0.2 0.022 14.8 0.1 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KIY72257.1 - 0.0018 18.1 0.0 0.0036 17.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 KIY72257.1 - 0.0055 16.1 0.1 0.39 10.1 0.0 2.3 1 1 1 2 2 2 1 Bacterial TniB protein AAA_7 PF12775.7 KIY72257.1 - 0.0055 16.2 0.0 0.011 15.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region Viral_helicase1 PF01443.18 KIY72257.1 - 0.01 15.6 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.6 KIY72257.1 - 0.013 15.1 0.0 0.057 13.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 KIY72257.1 - 0.017 14.2 0.0 0.047 12.7 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein IstB_IS21 PF01695.17 KIY72257.1 - 0.017 14.9 0.0 0.041 13.6 0.0 1.6 1 1 0 1 1 1 0 IstB-like ATP binding protein Methyltransf_31 PF13847.6 KIY72257.1 - 0.022 14.6 0.2 0.26 11.1 0.1 2.3 1 1 1 2 2 2 0 Methyltransferase domain Mg_chelatase PF01078.21 KIY72257.1 - 0.052 12.9 0.0 0.39 10.1 0.0 2.3 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 KIY72257.1 - 0.053 12.7 0.0 0.097 11.9 0.0 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain ATPase_2 PF01637.18 KIY72257.1 - 0.067 13.1 0.1 0.12 12.3 0.1 1.5 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_28 PF13521.6 KIY72257.1 - 0.073 13.3 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain PIF1 PF05970.14 KIY72257.1 - 0.079 12.1 0.1 2.8 7.0 0.1 2.2 1 1 1 2 2 2 0 PIF1-like helicase SNF2_N PF00176.23 KIY72257.1 - 0.12 11.1 0.0 0.21 10.3 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain TPR_6 PF13174.6 KIY72257.1 - 0.15 12.7 1.6 8.4 7.3 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Tfb5 PF06331.12 KIY72258.1 - 6.4e-23 80.5 0.2 7e-23 80.4 0.2 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 Acetyltransf_1 PF00583.25 KIY72259.1 - 1.7e-12 47.6 0.0 2.4e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KIY72259.1 - 1.1e-09 38.2 0.0 1.5e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KIY72259.1 - 1.5e-09 38.1 0.1 2.2e-09 37.6 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain zf-C2H2 PF00096.26 KIY72260.1 - 6e-12 45.3 17.0 0.00053 20.3 1.2 3.8 4 0 0 4 4 3 3 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 KIY72260.1 - 1e-11 44.4 10.1 3.5e-05 23.5 0.1 3.7 3 0 0 3 3 3 3 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 KIY72260.1 - 1.9e-06 28.2 13.2 0.013 16.3 0.6 3.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-BED PF02892.15 KIY72260.1 - 0.00045 20.2 9.1 1.4 9.0 0.2 3.3 1 1 2 3 3 3 2 BED zinc finger zf-Di19 PF05605.12 KIY72260.1 - 0.00071 19.8 9.7 0.0053 17.0 0.6 3.0 1 1 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 KIY72260.1 - 0.00072 19.9 15.5 0.03 14.8 0.4 4.3 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_2 PF12756.7 KIY72260.1 - 0.0019 18.5 7.4 0.27 11.6 8.0 2.5 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 KIY72260.1 - 0.01 16.2 0.2 0.01 16.2 0.2 3.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type CpXC PF14353.6 KIY72260.1 - 0.012 15.7 1.4 0.94 9.5 0.1 2.3 1 1 1 2 2 2 0 CpXC protein zf-C2H2_11 PF16622.5 KIY72260.1 - 0.024 14.4 0.1 0.024 14.4 0.1 2.8 3 0 0 3 3 2 0 zinc-finger C2H2-type zf-C2HE PF16278.5 KIY72260.1 - 0.047 14.2 4.6 1.3 9.6 0.1 2.9 2 1 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger Zn_ribbon_SprT PF17283.2 KIY72260.1 - 0.12 12.3 5.2 3.9 7.5 5.2 2.4 1 1 0 1 1 1 0 SprT-like zinc ribbon domain zf_C2H2_ZHX PF18387.1 KIY72260.1 - 0.15 11.8 7.7 0.66 9.7 0.1 3.2 2 1 1 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_jaz PF12171.8 KIY72260.1 - 0.22 11.9 7.1 0.34 11.3 0.1 3.4 4 0 0 4 4 3 0 Zinc-finger double-stranded RNA-binding OrsD PF12013.8 KIY72260.1 - 0.26 11.7 6.9 4.4 7.8 0.5 3.3 2 1 1 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf_UBZ PF18439.1 KIY72260.1 - 0.6 9.7 2.5 0.39 10.3 0.3 1.9 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger DUF629 PF04780.12 KIY72260.1 - 2.9 6.3 6.6 1.3 7.5 1.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF629) AA_permease PF00324.21 KIY72261.1 - 1.2e-138 462.7 38.7 1.4e-138 462.5 38.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KIY72261.1 - 2.2e-35 122.3 45.3 3e-35 121.9 45.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KIY72262.1 - 7.1e-135 450.3 39.6 8.5e-135 450.0 39.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KIY72262.1 - 2.2e-37 128.9 44.1 2.7e-37 128.6 44.1 1.0 1 0 0 1 1 1 1 Amino acid permease CTD PF12815.7 KIY72264.1 - 0.072 13.7 11.3 0.12 12.9 10.8 1.6 1 1 0 1 1 1 0 Spt5 C-terminal nonapeptide repeat binding Spt4 FAM176 PF14851.6 KIY72265.1 - 0.11 12.2 0.1 0.14 11.8 0.1 1.1 1 0 0 1 1 1 0 FAM176 family Questin_oxidase PF14027.6 KIY72268.1 - 5.6e-86 289.2 0.0 6.7e-86 288.9 0.0 1.1 1 0 0 1 1 1 1 Questin oxidase-like FAA_hydrolase PF01557.18 KIY72269.1 - 2.6e-58 197.3 0.0 3.2e-58 197.0 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DUF1730 PF08331.10 KIY72269.1 - 0.18 11.8 0.1 12 5.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1730) TFR_dimer PF04253.15 KIY72270.1 - 6.1e-21 74.8 0.0 1.9e-19 69.9 0.0 2.5 2 0 0 2 2 2 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 KIY72270.1 - 2.3e-17 63.3 0.0 6e-17 62.0 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KIY72270.1 - 1.7e-10 40.8 0.5 3.9e-10 39.6 0.5 1.6 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 KIY72270.1 - 0.12 12.0 0.0 0.17 11.6 0.0 1.4 1 1 0 1 1 1 0 Peptidase family M20/M25/M40 2OG-FeII_Oxy_3 PF13640.6 KIY72271.1 - 2e-10 41.4 0.0 3.4e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Sugar_tr PF00083.24 KIY72272.1 - 6e-111 371.5 16.0 7e-111 371.3 16.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY72272.1 - 6.9e-20 71.3 27.2 6.9e-20 71.3 27.2 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily TMEM107 PF14995.6 KIY72272.1 - 0.0053 17.2 0.3 0.02 15.3 0.3 1.9 1 0 0 1 1 1 1 Transmembrane protein LSM PF01423.22 KIY72273.1 - 6.2e-18 64.3 0.1 7.1e-18 64.1 0.1 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KIY72273.1 - 1.2e-05 25.4 0.0 1.4e-05 25.1 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 KIY72273.1 - 0.1 12.7 0.1 0.11 12.6 0.1 1.2 1 0 0 1 1 1 0 Scd6-like Sm domain AMP-binding PF00501.28 KIY72274.1 - 8.7e-84 281.6 0.0 1.1e-83 281.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KIY72274.1 - 5.4e-13 49.7 0.4 1e-12 48.8 0.4 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Macoilin PF09726.9 KIY72275.1 - 0.17 10.4 1.6 0.24 9.9 1.6 1.1 1 0 0 1 1 1 0 Macoilin family ArAE_2 PF10334.9 KIY72276.1 - 1.2e-53 182.4 0.0 2e-53 181.6 0.0 1.4 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 ArAE_2_N PF10337.9 KIY72276.1 - 2.3e-34 119.3 14.5 3.8e-33 115.2 10.2 3.5 2 1 0 2 2 2 1 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 KIY72276.1 - 3.6e-10 40.0 11.7 3.6e-10 40.0 11.7 3.3 2 1 1 3 3 3 1 Fusaric acid resistance protein-like SecD_SecF PF02355.16 KIY72276.1 - 0.066 12.6 0.2 0.066 12.6 0.2 2.6 3 0 0 3 3 3 0 Protein export membrane protein zf-C3HC4_3 PF13920.6 KIY72278.1 - 4e-06 26.6 7.6 6.9e-06 25.8 7.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIY72278.1 - 1.7e-05 25.0 11.1 3e-05 24.2 11.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KIY72278.1 - 7.1e-05 22.7 9.2 0.00012 22.0 9.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KIY72278.1 - 0.00019 21.2 10.9 0.00034 20.4 10.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KIY72278.1 - 0.0029 17.4 9.7 0.0061 16.4 9.7 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KIY72278.1 - 0.0034 17.4 6.7 0.0034 17.4 6.7 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_4 PF14570.6 KIY72278.1 - 0.15 11.9 7.5 0.3 10.9 7.5 1.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 KIY72278.1 - 0.16 12.1 5.4 0.31 11.2 5.4 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 KIY72278.1 - 0.5 10.6 11.5 1.1 9.5 11.5 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 KIY72278.1 - 0.6 10.0 11.4 1.3 8.9 11.4 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Baculo_IE-1 PF05290.11 KIY72278.1 - 0.63 10.0 3.7 1.4 8.9 3.7 1.5 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Sec2p PF06428.11 KIY72278.1 - 0.77 9.8 4.5 2.9 7.9 4.5 1.9 1 1 0 1 1 1 0 GDP/GTP exchange factor Sec2p FXMR_C2 PF16098.5 KIY72278.1 - 1 9.9 3.8 1.5 9.4 0.0 3.0 3 0 0 3 3 3 0 Fragile X-related mental retardation protein C-terminal region 2 FYVE PF01363.21 KIY72278.1 - 2.8 8.2 7.1 13 6.0 7.0 2.0 1 1 1 2 2 2 0 FYVE zinc finger PRKG1_interact PF15898.5 KIY72278.1 - 4.9 8.1 8.0 1.6 9.6 3.1 2.3 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain zf-HYPF PF07503.12 KIY72278.1 - 8.2 6.3 7.3 3.7 7.4 0.2 2.8 3 0 0 3 3 3 0 HypF finger Cytochrom_B561 PF03188.16 KIY72280.1 - 1e-11 45.1 13.0 1.9e-09 37.8 9.1 2.2 1 1 1 2 2 2 2 Eukaryotic cytochrome b561 Cation_efflux PF01545.21 KIY72280.1 - 0.00095 19.0 0.4 0.43 10.3 1.2 2.2 2 0 0 2 2 2 2 Cation efflux family COX3 PF00510.18 KIY72280.1 - 0.044 13.6 3.1 0.074 12.9 0.8 1.9 2 0 0 2 2 2 0 Cytochrome c oxidase subunit III DUF4079 PF13301.6 KIY72280.1 - 0.068 13.3 9.5 0.45 10.7 9.0 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF4079) Abhydrolase_9_N PF15420.6 KIY72280.1 - 1.5 8.7 10.6 71 3.3 9.0 3.2 2 1 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus DUF2427 PF10348.9 KIY72280.1 - 2.8 7.8 4.9 1.7 8.5 1.8 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF2427) Sugar_tr PF00083.24 KIY72281.1 - 5e-128 427.8 20.0 3.3e-127 425.1 20.0 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY72281.1 - 8.8e-16 57.8 40.1 1.9e-09 36.9 12.0 2.6 1 1 0 2 2 2 2 Major Facilitator Superfamily DUF2530 PF10745.9 KIY72281.1 - 1.4 9.2 6.9 0.14 12.4 0.5 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2530) Beach PF02138.18 KIY72282.1 - 1.9e-107 358.8 0.0 4.8e-107 357.4 0.0 1.7 2 0 0 2 2 2 1 Beige/BEACH domain Laminin_G_3 PF13385.6 KIY72282.1 - 5.6e-07 29.8 0.0 1.2e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily PH_BEACH PF14844.6 KIY72282.1 - 1.8e-06 28.0 0.0 3.7e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH DUF4704 PF15787.5 KIY72282.1 - 0.00096 18.5 0.1 0.01 15.1 0.2 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4704) WD40 PF00400.32 KIY72282.1 - 0.0012 19.6 0.2 13 6.8 0.0 3.9 3 0 0 3 3 3 2 WD domain, G-beta repeat Calici_PP_N PF08405.11 KIY72282.1 - 0.004 16.0 0.0 0.0073 15.2 0.0 1.3 1 0 0 1 1 1 1 Viral polyprotein N-terminal ChitinaseA_N PF08329.10 KIY72282.1 - 0.2 11.3 0.0 1 9.0 0.0 2.0 2 0 0 2 2 2 0 Chitinase A, N-terminal domain ABC_membrane PF00664.23 KIY72285.1 - 1.1e-66 225.3 25.9 2.7e-38 132.2 10.4 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KIY72285.1 - 4.2e-54 182.8 0.0 1.1e-29 103.7 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KIY72285.1 - 9.2e-13 48.1 0.8 0.0004 19.9 0.0 4.3 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KIY72285.1 - 2.1e-08 34.2 0.8 0.0072 16.4 0.0 3.0 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA_21 PF13304.6 KIY72285.1 - 8.9e-08 32.3 0.1 0.046 13.5 0.0 3.4 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KIY72285.1 - 1.2e-07 31.4 0.1 0.023 14.4 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KIY72285.1 - 2.6e-07 31.2 0.5 0.0094 16.3 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 KIY72285.1 - 1.4e-05 25.7 0.9 0.17 12.3 0.0 3.1 3 0 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 KIY72285.1 - 2.6e-05 24.2 0.1 0.25 11.2 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 KIY72285.1 - 0.00021 21.4 3.1 0.057 13.5 0.4 2.8 2 0 0 2 2 2 2 Dynamin family DUF815 PF05673.13 KIY72285.1 - 0.00039 19.7 0.3 0.096 11.8 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) FtsK_SpoIIIE PF01580.18 KIY72285.1 - 0.0005 19.5 0.0 0.28 10.5 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_22 PF13401.6 KIY72285.1 - 0.00069 19.9 0.8 2.1 8.6 0.1 3.1 2 1 0 2 2 2 2 AAA domain Roc PF08477.13 KIY72285.1 - 0.0011 19.2 0.2 1.9 8.7 0.1 2.7 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_30 PF13604.6 KIY72285.1 - 0.0015 18.3 1.5 1.9 8.2 0.0 3.1 2 1 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 KIY72285.1 - 0.0023 17.3 1.5 0.96 8.7 0.1 2.7 3 0 0 3 3 3 2 Zeta toxin AAA_15 PF13175.6 KIY72285.1 - 0.0024 17.7 3.1 0.51 10.0 0.0 3.0 3 0 0 3 3 3 1 AAA ATPase domain TrwB_AAD_bind PF10412.9 KIY72285.1 - 0.0031 16.5 1.0 0.52 9.2 0.1 2.4 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain MeaB PF03308.16 KIY72285.1 - 0.0033 16.4 1.1 0.87 8.5 0.2 2.4 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB NACHT PF05729.12 KIY72285.1 - 0.014 15.4 0.3 2.8 7.8 0.0 2.5 2 0 0 2 2 2 0 NACHT domain ATP-synt_ab PF00006.25 KIY72285.1 - 0.016 14.9 0.1 3.2 7.4 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain NB-ARC PF00931.22 KIY72285.1 - 0.018 14.3 0.1 2.1 7.5 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain AAA_7 PF12775.7 KIY72285.1 - 0.026 14.0 0.1 2.4 7.6 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_25 PF13481.6 KIY72285.1 - 0.03 13.9 0.0 0.52 9.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain MobB PF03205.14 KIY72285.1 - 0.038 13.9 0.6 6.4 6.7 0.1 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B SbcCD_C PF13558.6 KIY72285.1 - 0.073 13.3 0.1 3.1 8.1 0.0 3.1 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.7 KIY72285.1 - 0.089 11.7 0.3 1.1 8.1 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain cobW PF02492.19 KIY72285.1 - 0.11 12.1 1.4 2.1 7.9 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 KIY72285.1 - 0.11 12.2 1.5 13 5.5 0.1 3.0 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 KIY72285.1 - 0.12 12.1 0.1 9.8 5.9 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF87 PF01935.17 KIY72285.1 - 0.35 10.9 8.2 1.3 9.1 0.2 2.8 3 0 0 3 3 2 0 Helicase HerA, central domain HTH_31 PF13560.6 KIY72286.1 - 1.4e-06 28.5 0.0 1.6e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 KIY72286.1 - 0.00027 20.9 0.1 0.00032 20.7 0.1 1.1 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 KIY72286.1 - 0.00053 20.0 0.0 0.00064 19.7 0.0 1.0 1 0 0 1 1 1 1 Helix-turn-helix domain NIF3 PF01784.18 KIY72286.1 - 0.017 14.7 0.1 0.019 14.6 0.1 1.0 1 0 0 1 1 1 0 NIF3 (NGG1p interacting factor 3) Synaptobrevin PF00957.21 KIY72287.1 - 3.8e-30 103.5 0.1 5.7e-30 103.0 0.1 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 KIY72287.1 - 7e-24 83.7 0.0 1.2e-23 82.9 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Goodbye PF17109.5 KIY72288.1 - 7e-08 32.9 0.1 9.3e-08 32.6 0.1 1.2 1 0 0 1 1 1 1 fungal STAND N-terminal Goodbye domain Lactonase PF10282.9 KIY72289.1 - 1.8e-12 47.2 0.1 6e-09 35.6 0.1 3.3 2 2 1 3 3 3 2 Lactonase, 7-bladed beta-propeller Glyco_hydro_61 PF03443.14 KIY72290.1 - 1.2e-54 185.3 0.0 1.4e-54 185.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Fer2_3 PF13085.6 KIY72291.1 - 2.5e-32 111.1 0.0 3.9e-32 110.5 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 KIY72291.1 - 1.9e-10 41.1 6.4 1.9e-10 41.1 6.4 2.2 2 1 1 3 3 3 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 KIY72291.1 - 6e-07 29.5 4.2 6e-07 29.5 4.2 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 KIY72291.1 - 1.1e-06 29.0 7.8 1.1e-06 29.0 7.8 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer2 PF00111.27 KIY72291.1 - 0.0014 18.5 2.2 0.0028 17.6 0.3 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.7 KIY72291.1 - 0.0018 18.8 7.9 0.003 18.1 6.0 2.3 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 KIY72291.1 - 0.78 10.0 11.8 1.9 8.7 9.1 2.7 2 1 0 2 2 2 0 4Fe-4S dicluster domain Lysine_decarbox PF03641.14 KIY72292.1 - 4.3e-34 117.5 0.1 5.9e-34 117.0 0.1 1.1 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 KIY72292.1 - 1.5e-12 47.4 2.2 2.2e-12 46.8 2.2 1.2 1 0 0 1 1 1 1 SLOG cluster4 family F-box-like PF12937.7 KIY72293.1 - 1e-05 25.3 0.0 4.8e-05 23.2 0.0 2.3 1 1 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KIY72293.1 - 0.016 15.6 3.0 24 5.5 0.0 4.5 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KIY72293.1 - 0.22 11.3 1.0 4.8 7.0 0.0 3.4 3 1 0 3 3 3 0 Leucine rich repeat His_Phos_2 PF00328.22 KIY72295.1 - 0.005 16.2 0.0 0.7 9.2 0.0 2.2 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) ArfGap PF01412.18 KIY72296.1 - 6e-32 110.2 0.7 6e-32 110.2 0.7 1.7 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf Thaumatin PF00314.17 KIY72297.1 - 1.4e-72 243.8 14.2 1.6e-72 243.6 14.2 1.0 1 0 0 1 1 1 1 Thaumatin family Glyco_hydro_64 PF16483.5 KIY72297.1 - 0.00078 18.8 0.5 0.0026 17.1 0.0 1.9 2 0 0 2 2 2 1 Beta-1,3-glucanase TilS PF09179.11 KIY72298.1 - 0.13 12.8 0.0 0.46 11.0 0.0 1.9 2 0 0 2 2 2 0 TilS substrate binding domain EthD PF07110.11 KIY72299.1 - 7.4e-14 52.7 0.1 9.1e-14 52.4 0.1 1.1 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 KIY72299.1 - 0.00078 19.9 0.0 0.0012 19.3 0.0 1.4 1 1 0 1 1 1 1 Methylmuconolactone methyl-isomerase Abhydrolase_6 PF12697.7 KIY72300.1 - 6.5e-13 49.8 0.0 1.4e-12 48.7 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KIY72300.1 - 3.1e-11 43.4 0.0 2.2e-09 37.4 0.0 2.2 1 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIY72300.1 - 7.3e-07 28.7 0.0 2e-06 27.3 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 CMD PF02627.20 KIY72300.1 - 1.2e-06 28.5 0.0 4.5e-06 26.6 0.0 2.0 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family DmsC PF04976.12 KIY72300.1 - 0.031 13.8 0.0 0.052 13.0 0.0 1.3 1 0 0 1 1 1 0 DMSO reductase anchor subunit (DmsC) BAAT_C PF08840.11 KIY72300.1 - 0.096 12.6 0.0 0.45 10.4 0.0 1.9 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Esterase PF00756.20 KIY72300.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Fungal_trans PF04082.18 KIY72301.1 - 2.4e-07 30.1 0.0 2.7e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain AP_endonuc_2 PF01261.24 KIY72302.1 - 5.7e-23 81.5 0.0 9.2e-23 80.8 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Fungal_trans PF04082.18 KIY72303.1 - 3.7e-07 29.5 0.1 6.5e-07 28.6 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KIY72303.1 - 6.1e-07 29.5 9.4 0.0025 18.2 0.9 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KIY72303.1 - 0.0051 17.2 13.7 0.0088 16.4 2.9 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KIY72303.1 - 0.0073 17.1 1.6 0.0073 17.1 1.6 3.5 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KIY72303.1 - 0.0074 16.6 1.9 0.018 15.3 1.9 1.6 1 0 0 1 1 1 1 C2H2-type zinc ribbon zf-C2HE PF16278.5 KIY72303.1 - 0.0079 16.6 0.5 0.0079 16.6 0.5 2.1 2 0 0 2 2 2 1 C2HE / C2H2 / C2HC zinc-binding finger Zn_clus PF00172.18 KIY72303.1 - 0.27 11.4 7.9 0.68 10.1 7.9 1.7 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn-C2H2_12 PF18112.1 KIY72303.1 - 0.88 10.1 4.7 0.24 11.9 0.8 2.2 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain Synaptobrevin PF00957.21 KIY72304.1 - 5e-34 116.0 3.1 5.6e-34 115.8 3.1 1.0 1 0 0 1 1 1 1 Synaptobrevin TMEM117 PF15113.6 KIY72304.1 - 0.046 12.7 0.5 0.056 12.4 0.5 1.0 1 0 0 1 1 1 0 TMEM117 protein family Peptidase_M48_N PF16491.5 KIY72304.1 - 0.089 12.7 0.3 0.11 12.4 0.3 1.1 1 0 0 1 1 1 0 CAAX prenyl protease N-terminal, five membrane helices Shisa PF13908.6 KIY72304.1 - 0.22 11.7 0.3 0.33 11.2 0.1 1.4 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator DUF515 PF04415.12 KIY72304.1 - 0.83 8.0 5.9 0.86 7.9 5.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF515) DUF1129 PF06570.11 KIY72305.1 - 0.27 10.7 6.9 0.15 11.6 3.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) DUF2070 PF09843.9 KIY72305.1 - 4.6 5.4 13.2 5.8 5.1 13.2 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Pkinase PF00069.25 KIY72306.1 - 3.1e-73 246.4 0.0 4.4e-73 245.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY72306.1 - 4.8e-42 144.0 0.0 6.7e-42 143.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY72306.1 - 1.3e-09 37.8 0.0 1.8e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KIY72306.1 - 0.0083 15.5 0.1 0.016 14.6 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KIY72306.1 - 0.063 12.2 0.0 0.15 10.9 0.0 1.6 1 0 0 1 1 1 0 Haspin like kinase domain F-box-like PF12937.7 KIY72307.1 - 2.7e-09 36.8 0.1 6.7e-09 35.5 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY72307.1 - 0.025 14.5 2.3 0.6 10.1 0.7 2.9 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.7 KIY72308.1 - 0.0026 17.6 0.9 0.015 15.1 0.1 2.6 3 0 0 3 3 3 1 F-box-like NAD_binding_4 PF07993.12 KIY72309.1 - 1.2e-24 86.9 0.0 2.2e-24 86.0 0.0 1.4 1 1 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 KIY72309.1 - 9.3e-07 28.5 0.0 1.5e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KIY72309.1 - 0.00095 19.5 0.0 0.0061 16.9 0.0 2.4 1 1 0 1 1 1 1 Phosphopantetheine attachment site gpW PF02831.15 KIY72309.1 - 0.086 12.8 0.1 0.29 11.0 0.0 1.9 2 0 0 2 2 2 0 gpW Ribosomal_L24e PF01246.20 KIY72310.1 - 9e-31 105.9 0.3 9e-31 105.9 0.3 2.1 2 1 0 2 2 2 1 Ribosomal protein L24e Ets PF00178.22 KIY72310.1 - 0.082 13.4 0.7 0.19 12.2 0.7 1.5 1 0 0 1 1 1 0 Ets-domain FMO-like PF00743.19 KIY72314.1 - 2e-10 39.7 0.7 5.5e-09 35.0 0.1 2.7 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KIY72314.1 - 4.1e-09 36.0 0.0 1.3e-07 31.1 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KIY72314.1 - 3.4e-06 27.2 0.1 1.5e-05 25.1 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KIY72314.1 - 0.0019 17.5 0.0 0.055 12.7 0.0 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KIY72314.1 - 0.021 14.8 0.0 0.086 12.8 0.0 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding Sugar_tr PF00083.24 KIY72315.1 - 1.8e-65 221.6 22.9 2.1e-65 221.4 22.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY72315.1 - 4.1e-14 52.3 24.1 4.1e-14 52.3 24.1 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily ETRAMP PF09716.10 KIY72315.1 - 0.84 9.7 2.5 2.1 8.4 0.0 2.8 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Fungal_trans PF04082.18 KIY72316.1 - 6.5e-14 51.6 0.0 1.1e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY72316.1 - 3.3e-05 23.9 10.1 5.7e-05 23.2 10.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KIY72318.1 - 1e-17 64.1 0.3 1.9e-17 63.2 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY72318.1 - 0.00035 20.6 12.7 0.0007 19.7 12.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Prefoldin PF02996.17 KIY72318.1 - 1.1 9.2 2.3 5.7 6.9 0.3 2.2 2 0 0 2 2 2 0 Prefoldin subunit SET PF00856.28 KIY72319.1 - 1.9e-15 57.7 0.0 7.6e-15 55.7 0.0 1.9 1 1 0 1 1 1 1 SET domain zf-RING_5 PF14634.6 KIY72320.1 - 2.8e-07 30.4 9.4 4.3e-07 29.8 9.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KIY72320.1 - 1.9e-06 27.8 6.5 1.9e-06 27.8 6.5 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 KIY72320.1 - 6.7e-06 26.3 8.6 1.2e-05 25.6 8.6 1.4 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 KIY72320.1 - 8.2e-06 25.6 11.7 3.4e-05 23.6 11.8 1.9 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 Rtf2 PF04641.12 KIY72320.1 - 1.1e-05 25.0 0.2 2.2e-05 24.0 0.2 1.6 1 1 1 2 2 2 1 Rtf2 RING-finger zf-C3HC4_3 PF13920.6 KIY72320.1 - 3.3e-05 23.7 10.8 6.9e-05 22.6 10.8 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIY72320.1 - 3.7e-05 23.5 8.6 6.9e-05 22.6 8.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TRAF_BIRC3_bd PF16673.5 KIY72320.1 - 0.00012 21.8 2.1 0.0015 18.3 3.7 2.0 2 0 0 2 2 2 1 TNF receptor-associated factor BIRC3 binding domain zf-C3HC4_2 PF13923.6 KIY72320.1 - 0.00031 20.5 12.4 0.0011 18.7 12.4 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) P21-Arc PF04062.14 KIY72320.1 - 0.00032 20.8 0.1 0.00087 19.4 0.0 1.7 2 1 0 2 2 2 1 ARP2/3 complex ARPC3 (21 kDa) subunit zf-RING_6 PF14835.6 KIY72320.1 - 0.0058 16.5 1.2 0.0058 16.5 1.2 1.8 1 1 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 KIY72320.1 - 0.0079 16.3 7.0 0.036 14.2 7.2 2.0 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING Rabaptin PF03528.15 KIY72320.1 - 0.0082 14.9 1.7 0.01 14.6 1.7 1.1 1 0 0 1 1 1 1 Rabaptin Dynactin_p22 PF07426.11 KIY72320.1 - 0.0092 15.8 1.1 1.7 8.5 0.3 2.3 1 1 0 2 2 2 1 Dynactin subunit p22 DUF2408 PF10303.9 KIY72320.1 - 0.023 15.3 1.5 0.023 15.2 0.6 1.4 2 0 0 2 2 1 0 Protein of unknown function (DUF2408) Fib_alpha PF08702.10 KIY72320.1 - 0.027 14.6 2.5 0.044 14.0 2.5 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family bZIP_1 PF00170.21 KIY72320.1 - 0.029 14.5 0.8 1.6 8.9 0.1 2.4 2 0 0 2 2 2 0 bZIP transcription factor zf-RING_4 PF14570.6 KIY72320.1 - 0.15 11.9 8.1 0.25 11.1 8.1 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Lebercilin PF15619.6 KIY72320.1 - 0.17 11.5 9.8 0.074 12.7 6.8 1.8 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Rad50_zn_hook PF04423.14 KIY72320.1 - 0.19 11.6 4.7 0.87 9.5 0.2 3.2 3 0 0 3 3 3 0 Rad50 zinc hook motif DHR10 PF18595.1 KIY72320.1 - 0.43 10.6 6.3 1.2 9.3 6.3 1.6 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain Prefoldin PF02996.17 KIY72320.1 - 1.1 9.2 5.4 2.6 8.0 0.4 2.6 2 1 1 3 3 3 0 Prefoldin subunit CEP63 PF17045.5 KIY72320.1 - 1.3 8.9 10.9 2.5 7.9 10.9 1.4 1 1 0 1 1 1 0 Centrosomal protein of 63 kDa CorA PF01544.18 KIY72320.1 - 1.6 8.0 4.4 7.2 5.8 4.5 1.8 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein DUF4200 PF13863.6 KIY72320.1 - 1.6 9.2 11.1 2.4 8.6 6.9 2.4 2 1 1 3 3 2 0 Domain of unknown function (DUF4200) zf-rbx1 PF12678.7 KIY72320.1 - 1.8 8.9 7.1 3.5 8.0 7.1 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain FYVE PF01363.21 KIY72320.1 - 2.1 8.6 7.7 4.7 7.4 3.4 2.3 1 1 1 2 2 2 0 FYVE zinc finger APG6_N PF17675.1 KIY72320.1 - 2.2 8.8 8.5 7.6 7.1 8.3 2.0 1 1 1 2 2 2 0 Apg6 coiled-coil region FAM76 PF16046.5 KIY72320.1 - 5.6 6.2 12.0 1.4 8.2 2.7 2.2 2 0 0 2 2 2 0 FAM76 protein zf-RING_UBOX PF13445.6 KIY72321.1 - 5.2e-09 36.0 4.4 1.5e-08 34.6 4.4 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KIY72321.1 - 1.7e-08 34.3 8.8 2.5e-08 33.7 8.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KIY72321.1 - 2.8e-07 30.3 6.4 4.4e-07 29.7 6.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIY72321.1 - 1.5e-06 28.4 9.5 2.4e-06 27.8 9.5 1.3 1 0 0 1 1 1 1 Ring finger domain FYVE PF01363.21 KIY72321.1 - 0.00011 22.3 8.2 0.0022 18.1 7.2 2.2 1 1 1 2 2 2 2 FYVE zinc finger Prok-RING_4 PF14447.6 KIY72321.1 - 0.00011 21.9 12.0 0.00081 19.2 12.0 2.1 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KIY72321.1 - 0.00031 20.6 9.4 0.00057 19.7 9.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KIY72321.1 - 0.00047 19.9 10.7 0.0013 18.5 10.7 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KIY72321.1 - 0.0007 19.7 8.1 0.0022 18.1 8.1 1.9 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 KIY72321.1 - 0.084 12.7 6.8 0.26 11.1 6.8 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Rtf2 PF04641.12 KIY72321.1 - 0.19 11.1 1.6 0.27 10.6 1.6 1.3 1 1 0 1 1 1 0 Rtf2 RING-finger zf-RING_11 PF17123.5 KIY72321.1 - 0.71 9.7 6.7 0.75 9.6 4.5 2.1 2 0 0 2 2 2 0 RING-like zinc finger DZR PF12773.7 KIY72321.1 - 1.1 9.3 9.2 16 5.6 9.2 2.2 1 1 0 1 1 1 0 Double zinc ribbon zf-RING_6 PF14835.6 KIY72321.1 - 4.3 7.3 8.6 8.6 6.3 4.0 2.3 1 1 1 2 2 2 0 zf-RING of BARD1-type protein Transket_pyr PF02779.24 KIY72322.1 - 1.2e-59 201.0 0.0 1.7e-59 200.5 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 KIY72322.1 - 3.8e-44 150.0 0.0 6e-44 149.4 0.0 1.3 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal E1_dh PF00676.20 KIY72322.1 - 1.4e-36 126.0 0.0 2.2e-36 125.3 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component ANT PF03374.14 KIY72323.1 - 0.032 14.5 0.3 0.042 14.2 0.3 1.1 1 0 0 1 1 1 0 Phage antirepressor protein KilAC domain zf-RING_5 PF14634.6 KIY72324.1 - 6e-09 35.7 9.9 1.1e-08 34.9 9.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KIY72324.1 - 5.2e-07 29.9 10.3 5.2e-07 29.9 10.3 1.8 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KIY72324.1 - 1.1e-06 28.4 7.3 2.2e-06 27.4 7.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KIY72324.1 - 6.4e-06 25.9 11.4 2.2e-05 24.2 11.5 1.8 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KIY72324.1 - 1.7e-05 24.7 8.1 4.5e-05 23.4 8.1 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KIY72324.1 - 2.1e-05 24.3 10.3 2.1e-05 24.3 10.3 1.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KIY72324.1 - 3.1e-05 24.1 6.0 3.1e-05 24.1 6.0 1.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 KIY72324.1 - 6.8e-05 23.1 8.9 0.00013 22.1 8.9 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KIY72324.1 - 0.00046 20.0 14.9 0.00069 19.4 13.1 2.2 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KIY72324.1 - 0.0058 16.7 3.3 0.01 15.9 3.3 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-UDP PF14569.6 KIY72324.1 - 0.008 16.3 2.0 0.016 15.3 2.0 1.5 1 0 0 1 1 1 1 Zinc-binding RING-finger zf-RING_4 PF14570.6 KIY72324.1 - 0.022 14.6 5.5 0.056 13.2 5.5 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain FYVE PF01363.21 KIY72324.1 - 0.044 13.9 7.6 0.14 12.3 7.6 1.8 1 1 0 1 1 1 0 FYVE zinc finger HypA PF01155.19 KIY72324.1 - 0.19 11.7 2.6 0.26 11.3 1.3 1.8 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 KIY72324.1 - 0.31 11.1 4.5 0.18 11.9 1.7 1.9 2 0 0 2 2 2 0 Double zinc ribbon zf-Nse PF11789.8 KIY72324.1 - 0.73 9.7 6.1 1.4 8.8 6.1 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_10 PF16685.5 KIY72324.1 - 0.85 9.8 8.6 7.7 6.7 8.6 2.3 1 1 1 2 2 2 0 zinc RING finger of MSL2 DUF1272 PF06906.11 KIY72324.1 - 2.2 8.4 6.5 5.1 7.3 6.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1272) Acyltransferase PF01553.21 KIY72325.1 - 3e-14 52.8 0.0 5.2e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Phage_r1t_holin PF16945.5 KIY72325.1 - 0.0026 17.9 0.2 0.78 10.0 0.0 2.9 2 0 0 2 2 2 2 Putative lactococcus lactis phage r1t holin Sec61_beta PF03911.16 KIY72326.1 - 2.8e-18 65.7 0.5 3.6e-18 65.3 0.5 1.2 1 0 0 1 1 1 1 Sec61beta family zf-RING_2 PF13639.6 KIY72328.1 - 5.2e-08 33.1 14.1 1.1e-07 32.1 14.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KIY72328.1 - 8.7e-07 28.8 12.6 1.6e-06 27.9 12.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KIY72328.1 - 7.2e-06 25.8 7.6 7.2e-06 25.8 7.6 2.4 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KIY72328.1 - 8e-06 25.8 8.9 2.8e-05 24.0 7.1 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KIY72328.1 - 2.4e-05 24.4 11.3 0.00017 21.7 11.6 2.3 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING YscO PF07321.12 KIY72328.1 - 0.00022 21.2 2.9 0.00032 20.7 2.9 1.3 1 0 0 1 1 1 1 Type III secretion protein YscO zf-C3HC4 PF00097.25 KIY72328.1 - 0.00081 19.2 14.2 0.0022 17.8 14.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KIY72328.1 - 0.0012 18.6 14.1 0.0031 17.3 14.1 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Filament PF00038.21 KIY72328.1 - 0.0029 17.3 1.6 0.0041 16.8 1.6 1.2 1 0 0 1 1 1 1 Intermediate filament protein zf-RING_4 PF14570.6 KIY72328.1 - 0.0034 17.1 12.2 0.0063 16.3 12.2 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain HrpB7 PF09486.10 KIY72328.1 - 0.0037 17.7 1.1 0.0037 17.7 1.1 1.5 2 0 0 2 2 1 1 Bacterial type III secretion protein (HrpB7) HMMR_C PF15908.5 KIY72328.1 - 0.01 16.1 1.4 0.016 15.4 1.4 1.4 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor C-terminal FliS_cochap PF16522.5 KIY72328.1 - 0.024 14.6 1.3 0.049 13.6 1.0 1.6 1 1 1 2 2 2 0 Flagellar FLiS export co-chaperone, HP1076 JIP_LZII PF16471.5 KIY72328.1 - 0.032 14.4 1.3 0.055 13.6 1.3 1.3 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II zf-rbx1 PF12678.7 KIY72328.1 - 0.04 14.2 9.5 0.15 12.4 9.5 2.0 1 0 0 1 1 1 0 RING-H2 zinc finger domain Tho2 PF11262.8 KIY72328.1 - 0.044 13.0 1.1 0.051 12.8 1.1 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 TMF_DNA_bd PF12329.8 KIY72328.1 - 0.049 13.6 3.8 0.084 12.9 3.8 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Rtf2 PF04641.12 KIY72328.1 - 0.051 12.9 9.3 0.16 11.3 9.3 1.9 1 1 0 1 1 1 0 Rtf2 RING-finger DivIC PF04977.15 KIY72328.1 - 0.092 12.5 3.8 0.15 11.8 3.6 1.5 1 1 0 1 1 1 0 Septum formation initiator zf-ANAPC11 PF12861.7 KIY72328.1 - 0.38 10.9 5.9 0.95 9.6 5.9 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF1272 PF06906.11 KIY72328.1 - 0.57 10.3 11.1 0.55 10.4 9.6 1.8 2 0 0 2 2 1 0 Protein of unknown function (DUF1272) zf-RING_6 PF14835.6 KIY72328.1 - 1.8 8.5 8.5 6.1 6.8 8.5 1.9 1 1 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_11 PF17123.5 KIY72328.1 - 2.2 8.1 12.7 1.3 8.8 9.9 2.2 2 0 0 2 2 2 0 RING-like zinc finger FAM76 PF16046.5 KIY72328.1 - 4.1 6.7 12.6 5.5 6.2 0.4 2.3 2 0 0 2 2 2 0 FAM76 protein MbeD_MobD PF04899.12 KIY72329.1 - 0.0023 18.0 0.0 0.0044 17.1 0.0 1.5 1 0 0 1 1 1 1 MbeD/MobD like zf-RING_UBOX PF13445.6 KIY72329.1 - 0.029 14.4 5.1 0.079 13.0 4.8 2.0 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 KIY72329.1 - 0.11 12.4 14.8 0.22 11.5 14.8 1.5 1 0 0 1 1 1 0 zinc-RING finger domain Prok-RING_4 PF14447.6 KIY72329.1 - 0.99 9.3 12.5 1.9 8.4 12.5 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KIY72329.1 - 5.3 7.5 17.4 2 8.8 13.3 2.2 2 1 0 2 2 2 0 Ring finger domain ABC1 PF03109.16 KIY72330.1 - 5.5e-25 87.8 0.0 1.3e-24 86.6 0.0 1.6 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 KIY72330.1 - 0.031 14.2 0.2 0.1 12.5 0.2 1.8 1 0 0 1 1 1 0 Phosphotransferase enzyme family ThrE PF06738.12 KIY72332.1 - 7.7e-49 166.2 25.4 8.8e-49 166.0 10.2 2.2 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 KIY72332.1 - 3.4e-08 33.7 26.2 2.8e-07 30.7 8.6 2.5 2 1 0 2 2 2 2 Threonine/Serine exporter, ThrE DUF1980 PF09323.10 KIY72332.1 - 0.029 14.3 0.4 0.32 10.9 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) F-box-like PF12937.7 KIY72333.1 - 4.3e-07 29.7 0.1 9.1e-07 28.7 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY72333.1 - 0.00049 19.9 0.0 0.0012 18.7 0.0 1.6 1 0 0 1 1 1 1 F-box domain Xpo1 PF08389.12 KIY72334.1 - 5.8e-20 71.9 4.0 2.5e-19 69.8 0.3 3.9 4 2 0 4 4 4 1 Exportin 1-like protein HEAT PF02985.22 KIY72334.1 - 0.00023 21.1 0.1 0.078 13.3 0.0 4.4 4 0 0 4 4 4 1 HEAT repeat IBN_N PF03810.19 KIY72334.1 - 0.013 15.4 0.1 9.4 6.2 0.0 4.1 5 0 0 5 5 5 0 Importin-beta N-terminal domain ERAP1_C PF11838.8 KIY72334.1 - 0.039 13.5 0.1 0.13 11.7 0.1 1.9 1 0 0 1 1 1 0 ERAP1-like C-terminal domain HEAT_2 PF13646.6 KIY72334.1 - 0.06 13.7 0.1 12 6.4 0.0 3.3 2 0 0 2 2 2 0 HEAT repeats CDPS PF16715.5 KIY72334.1 - 0.079 12.6 0.9 0.15 11.7 0.0 1.8 2 0 0 2 2 2 0 Cyclodipeptide synthase TPR_10 PF13374.6 KIY72334.1 - 0.16 11.9 0.1 0.7 9.8 0.1 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat zf-C3HC4_3 PF13920.6 KIY72335.1 - 3.4e-09 36.4 17.8 3.4e-09 36.4 17.8 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) BHD_2 PF10404.9 KIY72335.1 - 0.04 14.9 4.5 0.25 12.3 4.5 2.1 1 1 0 1 1 1 0 Rad4 beta-hairpin domain 2 Mis12 PF05859.12 KIY72336.1 - 3.6e-32 111.3 0.9 3.6e-32 111.3 0.9 1.9 2 0 0 2 2 2 1 Mis12 protein tRNA-synt_2c PF01411.19 KIY72336.1 - 0.007 14.9 0.1 0.0092 14.5 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) Lzipper-MIP1 PF14389.6 KIY72336.1 - 0.011 16.0 5.0 0.096 13.0 2.4 2.7 3 0 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 FeoB_Cyto PF17910.1 KIY72336.1 - 0.082 13.5 0.7 9.5 6.8 0.4 2.6 2 0 0 2 2 2 0 FeoB cytosolic helical domain Alba PF01918.21 KIY72337.1 - 0.00084 19.1 0.0 0.9 9.4 0.1 2.8 2 1 0 2 2 2 2 Alba Dioxygenase_C PF00775.21 KIY72338.1 - 4e-12 46.0 0.3 8.1e-12 44.9 0.3 1.5 1 1 0 1 1 1 1 Dioxygenase SpaA PF17802.1 KIY72338.1 - 0.075 13.4 0.3 0.24 11.8 0.0 2.0 2 0 0 2 2 2 0 Prealbumin-like fold domain Cullin PF00888.22 KIY72339.1 - 4.2e-201 669.8 0.0 5.5e-201 669.4 0.0 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KIY72339.1 - 3e-26 91.2 0.3 1.1e-25 89.5 0.2 2.1 2 0 0 2 2 2 1 Cullin protein neddylation domain DUF4413 PF14372.6 KIY72339.1 - 0.042 14.2 0.0 0.17 12.2 0.0 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) Ribosomal_S7 PF00177.21 KIY72340.1 - 5.2e-17 61.9 0.0 6.9e-17 61.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Snurportin1 PF11538.8 KIY72341.1 - 0.00013 22.1 4.1 0.00013 22.1 4.1 1.7 2 0 0 2 2 2 1 Snurportin1 DnaJ_C PF01556.18 KIY72343.1 - 4.6e-30 104.6 0.0 7.3e-30 104.0 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KIY72343.1 - 4.9e-23 81.0 8.1 7.3e-23 80.5 8.1 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KIY72343.1 - 8.8e-14 51.6 17.7 1.5e-13 50.9 17.7 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.19 KIY72343.1 - 0.00014 21.9 4.4 0.22 11.5 0.1 2.3 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Anti-TRAP PF15777.5 KIY72343.1 - 0.015 15.2 11.0 0.12 12.4 1.2 2.5 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein TackOD1 PF18551.1 KIY72343.1 - 0.068 12.8 0.4 0.068 12.8 0.4 2.3 2 1 1 3 3 3 0 Thaumarchaeal output domain 1 Stevor PF17410.2 KIY72343.1 - 0.075 12.6 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame zinc_ribbon_6 PF14599.6 KIY72343.1 - 1.5 8.9 6.5 0.46 10.5 0.6 2.5 2 0 0 2 2 2 0 Zinc-ribbon Lar_restr_allev PF14354.6 KIY72343.1 - 8.9 6.8 11.3 23 5.4 0.3 3.6 1 1 1 2 2 2 0 Restriction alleviation protein Lar E1-E2_ATPase PF00122.20 KIY72345.1 - 8.6e-37 126.4 8.4 1e-29 103.4 0.1 3.3 3 1 1 4 4 4 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 KIY72345.1 - 7.9e-28 97.4 3.7 7.9e-28 97.4 3.7 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KIY72345.1 - 3.2e-21 76.6 0.0 1.4e-20 74.5 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KIY72345.1 - 1.9e-17 63.1 0.0 3.8e-17 62.2 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KIY72345.1 - 2.6e-15 55.9 0.0 6.1e-15 54.7 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KIY72345.1 - 0.00048 19.9 1.0 0.0029 17.4 0.6 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KIY72345.1 - 0.14 12.6 0.1 0.26 11.6 0.1 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF5418 PF17439.2 KIY72345.1 - 3 7.9 7.4 0.21 11.7 1.6 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5418) tRNA-synt_1b PF00579.25 KIY72346.1 - 4e-62 210.2 0.0 7.9e-62 209.2 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) DEAD PF00270.29 KIY72349.1 - 1.9e-22 79.9 0.0 5.7e-22 78.3 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIY72349.1 - 5.2e-20 71.9 0.0 1.6e-16 60.7 0.0 3.0 3 0 0 3 3 3 2 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 KIY72349.1 - 7.5e-10 39.4 2.3 2.2e-09 37.9 1.0 2.6 3 0 0 3 3 3 1 RecQ zinc-binding RQC PF09382.10 KIY72349.1 - 6.3e-07 29.2 0.0 1.9e-06 27.6 0.0 1.8 2 0 0 2 2 2 1 RQC domain ResIII PF04851.15 KIY72349.1 - 9.1e-05 22.5 0.0 0.00016 21.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KIY72349.1 - 0.059 13.7 0.1 0.33 11.2 0.1 2.3 1 1 0 1 1 1 0 AAA domain HEM4 PF02602.15 KIY72349.1 - 0.068 12.5 0.0 0.26 10.6 0.0 1.9 2 0 0 2 2 2 0 Uroporphyrinogen-III synthase HemD RasGAP PF00616.19 KIY72350.1 - 1e-60 205.0 0.3 1e-59 201.8 0.0 2.6 3 0 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 KIY72350.1 - 1.6e-39 135.1 1.6 1.6e-39 135.1 1.6 2.1 2 0 0 2 2 2 1 RasGAP C-terminus Asp PF00026.23 KIY72351.1 - 8.7e-49 166.6 0.2 1.2e-48 166.1 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIY72351.1 - 1.2e-09 38.7 5.5 3.1e-08 34.1 5.5 2.5 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KIY72351.1 - 0.042 14.5 1.5 0.24 12.1 0.4 2.8 3 1 0 3 3 3 0 Aspartyl protease 7tm_2 PF00002.24 KIY72352.1 - 0.0011 18.3 5.2 0.0016 17.8 5.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) UPF0220 PF05255.11 KIY72352.1 - 0.055 13.0 0.7 0.1 12.2 0.7 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0220) TctB PF07331.11 KIY72354.1 - 1.1 9.5 8.7 0.99 9.7 6.5 2.0 1 1 1 2 2 2 0 Tripartite tricarboxylate transporter TctB family DUF2368 PF10166.9 KIY72354.1 - 5.8 6.5 5.7 2.1 8.0 2.3 2.0 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2368) Acetyltransf_8 PF13523.6 KIY72355.1 - 4.2e-28 97.9 0.2 6.5e-28 97.2 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain ECH_1 PF00378.20 KIY72356.1 - 5.4e-45 153.7 0.0 1.3e-42 145.9 0.0 2.0 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KIY72356.1 - 6e-22 78.6 1.7 1.9e-18 67.1 0.9 2.9 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Pec_lyase_C PF00544.19 KIY72357.1 - 3.5e-11 43.1 12.6 1.6e-09 37.7 11.8 3.1 1 1 1 2 2 2 2 Pectate lyase MaoC_dehydratas PF01575.19 KIY72358.1 - 2.5e-30 104.6 0.0 4e-30 103.9 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 KIY72358.1 - 1.3e-06 28.6 0.0 1.7e-05 25.0 0.0 2.1 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase ATP-synt_10 PF05176.14 KIY72359.1 - 1.7e-58 197.9 0.0 2.1e-58 197.6 0.0 1.0 1 0 0 1 1 1 1 ATP10 protein Qn_am_d_aIV PF09100.10 KIY72359.1 - 0.038 13.8 0.0 0.058 13.2 0.0 1.3 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain IV Na_Ca_ex PF01699.24 KIY72360.1 - 6.5e-28 97.6 41.8 4.1e-21 75.5 16.6 3.3 3 1 0 3 3 3 2 Sodium/calcium exchanger protein AzlD PF05437.12 KIY72360.1 - 0.87 9.8 10.8 0.93 9.7 2.0 3.9 3 1 1 4 4 4 0 Branched-chain amino acid transport protein (AzlD) F-box-like PF12937.7 KIY72361.1 - 0.047 13.6 4.5 0.031 14.1 1.4 2.2 2 0 0 2 2 2 0 F-box-like LRR_4 PF12799.7 KIY72361.1 - 0.096 13.1 0.8 4.6 7.8 0.1 3.4 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) DOR PF14839.6 KIY72361.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 DOR family Erg28 PF03694.13 KIY72362.1 - 1.4e-40 138.1 7.1 1.8e-40 137.7 7.1 1.2 1 0 0 1 1 1 1 Erg28 like protein EOS1 PF12326.8 KIY72362.1 - 0.0096 15.9 1.4 0.035 14.1 1.0 1.9 1 1 1 2 2 2 1 N-glycosylation protein Cwf_Cwc_15 PF04889.12 KIY72363.1 - 0.18 11.5 4.4 0.32 10.7 4.4 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein YL1 PF05764.13 KIY72363.1 - 0.41 10.7 9.3 0.087 12.9 5.4 1.8 2 0 0 2 2 2 0 YL1 nuclear protein adh_short PF00106.25 KIY72364.1 - 3.9e-84 281.0 19.3 1.3e-43 148.7 5.3 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KIY72364.1 - 4.3e-68 229.3 15.6 8.3e-34 117.2 3.0 2.6 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIY72364.1 - 4.3e-28 98.4 11.3 3.9e-15 56.2 2.2 2.2 2 0 0 2 2 2 2 KR domain THF_DHG_CYH_C PF02882.19 KIY72364.1 - 0.00011 21.5 4.8 0.0016 17.8 0.8 2.5 2 0 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain TcdB_toxin_midN PF12256.8 KIY72364.1 - 0.27 10.6 1.2 6 6.2 0.0 2.4 2 0 0 2 2 2 0 Insecticide toxin TcdB middle/N-terminal region 3HCDH_N PF02737.18 KIY72364.1 - 0.36 10.7 10.8 1.6 8.6 1.9 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PglL_A PF15864.5 KIY72364.1 - 0.72 9.6 8.2 6.4 6.6 1.0 2.6 2 0 0 2 2 2 0 Protein glycosylation ligase Cyclin_N PF00134.23 KIY72365.1 - 1.4e-42 144.4 0.1 2.9e-42 143.4 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KIY72365.1 - 1.1e-24 86.8 0.0 2.1e-24 85.9 0.0 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain Bac_rhamnosid6H PF17389.2 KIY72366.1 - 2.1e-16 60.1 1.7 3.8e-15 56.0 0.7 2.1 2 0 0 2 2 2 2 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Trehalase PF01204.18 KIY72366.1 - 0.0001 21.3 0.3 0.00014 20.8 0.3 1.1 1 0 0 1 1 1 1 Trehalase Bac_rhamnosid_C PF17390.2 KIY72366.1 - 0.00022 20.9 0.0 0.0004 20.1 0.0 1.4 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain Pkinase PF00069.25 KIY72368.1 - 3.2e-50 171.0 0.0 4.3e-50 170.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY72368.1 - 3.3e-26 92.1 0.0 4e-26 91.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KIY72368.1 - 0.0019 18.2 0.0 0.0035 17.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 KIY72368.1 - 0.0025 17.5 0.0 0.045 13.4 0.0 2.3 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KIY72368.1 - 0.027 13.8 0.0 0.049 13.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KIY72368.1 - 0.084 12.5 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase CS PF04969.16 KIY72369.1 - 1.4e-09 38.8 0.0 2.7e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 CS domain G-patch PF01585.23 KIY72371.1 - 5.8e-09 35.7 0.4 9.6e-09 35.0 0.4 1.4 1 0 0 1 1 1 1 G-patch domain FHA PF00498.26 KIY72371.1 - 5.6e-07 29.8 0.0 1.2e-06 28.7 0.0 1.6 1 1 0 1 1 1 1 FHA domain GATA PF00320.27 KIY72372.1 - 4.5e-14 51.8 3.9 1.2e-13 50.4 3.9 1.8 1 0 0 1 1 1 1 GATA zinc finger SAC3_GANP PF03399.16 KIY72373.1 - 2.6e-49 168.2 0.1 6.5e-49 166.9 0.0 1.6 2 0 0 2 2 2 1 SAC3/GANP family ASXH PF13919.6 KIY72373.1 - 0.15 12.1 1.4 0.48 10.4 1.4 1.8 1 0 0 1 1 1 0 Asx homology domain aGPT-Pplase1 PF18723.1 KIY72374.1 - 2e-93 312.9 0.0 2.4e-93 312.6 0.0 1.1 1 0 0 1 1 1 1 alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 1 DUF4078 PF13300.6 KIY72375.1 - 1.3e-10 41.4 1.3 1.3e-10 41.4 1.3 3.1 3 0 0 3 3 3 2 Domain of unknown function (DUF4078) WLM PF08325.10 KIY72376.1 - 1.1e-34 120.2 5.5 1.2e-32 113.5 5.5 2.3 1 1 0 1 1 1 1 WLM domain zf-RanBP PF00641.18 KIY72376.1 - 1.1e-08 34.2 2.7 1.7e-08 33.6 2.7 1.3 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others DUF45 PF01863.17 KIY72376.1 - 2.2e-05 24.6 0.2 6.1e-05 23.2 0.2 1.8 1 0 0 1 1 1 1 Protein of unknown function DUF45 SprT-like PF10263.9 KIY72376.1 - 0.0098 15.7 0.1 0.024 14.5 0.1 1.6 1 0 0 1 1 1 1 SprT-like family MFS_1 PF07690.16 KIY72377.1 - 5.8e-24 84.7 77.7 4.2e-17 62.1 40.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KIY72377.1 - 0.15 10.9 23.2 0.083 11.7 3.7 3.3 3 0 0 3 3 3 0 MFS_1 like family MFS_1 PF07690.16 KIY72378.1 - 4.1e-18 65.4 56.3 1.1e-14 54.2 43.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PRMT5 PF05185.16 KIY72379.1 - 4.4e-60 202.5 0.0 6.3e-60 202.0 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_TIM PF17285.2 KIY72379.1 - 1.3e-53 181.9 0.0 1.7e-53 181.5 0.0 1.1 1 0 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5_C PF17286.2 KIY72379.1 - 1.2e-52 178.4 0.0 1.7e-52 177.9 0.0 1.2 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Methyltransf_25 PF13649.6 KIY72379.1 - 0.0002 22.0 0.0 0.0006 20.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain DSBA PF01323.20 KIY72382.1 - 1.1e-19 71.0 0.0 1.3e-19 70.7 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 KIY72382.1 - 0.0001 22.5 0.0 0.0016 18.6 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin Frag1 PF10277.9 KIY72383.1 - 6.6e-39 133.7 13.7 7.7e-39 133.5 13.7 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF998 PF06197.13 KIY72383.1 - 0.00041 20.0 10.2 0.00041 20.0 10.2 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF998) DUF2231 PF09990.9 KIY72383.1 - 0.017 15.5 2.1 0.044 14.2 2.1 1.7 1 0 0 1 1 1 0 Predicted membrane protein (DUF2231) EI24 PF07264.11 KIY72383.1 - 0.15 12.3 18.2 0.33 11.2 18.2 1.6 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) DUF4271 PF14093.6 KIY72383.1 - 0.59 10.0 16.3 0.094 12.6 11.4 1.9 1 1 0 2 2 2 0 Domain of unknown function (DUF4271) Peptidase_U4 PF03419.13 KIY72383.1 - 0.83 8.9 8.3 0.22 10.8 5.1 1.6 1 1 1 2 2 2 0 Sporulation factor SpoIIGA DUF2070 PF09843.9 KIY72383.1 - 2.4 6.3 10.0 3 6.0 10.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Glyco_hydro_47 PF01532.20 KIY72384.1 - 1.8e-116 389.7 0.0 1e-115 387.3 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 HMG_box PF00505.19 KIY72385.1 - 2.7e-12 46.9 1.3 4.7e-12 46.2 1.3 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KIY72385.1 - 0.0013 19.3 0.4 0.0024 18.4 0.4 1.4 1 0 0 1 1 1 1 HMG-box domain WD40 PF00400.32 KIY72387.1 - 3.4e-17 62.5 12.5 0.0044 17.8 1.2 6.0 7 1 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY72387.1 - 2.2e-10 40.7 0.1 0.00082 19.6 0.1 4.8 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIY72387.1 - 0.0012 18.8 0.1 0.088 12.7 0.0 2.6 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KIY72387.1 - 0.0048 16.3 0.0 0.029 13.7 0.0 2.2 2 1 0 3 3 3 1 WD40-like domain Frtz PF11768.8 KIY72387.1 - 0.073 11.4 0.0 1.2 7.3 0.0 2.2 1 1 1 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz F-box-like PF12937.7 KIY72388.1 - 3e-05 23.8 0.2 0.0001 22.1 0.2 2.0 1 0 0 1 1 1 1 F-box-like ROS_MUCR PF05443.11 KIY72389.1 - 8.7e-05 22.6 3.0 0.00025 21.1 2.0 2.2 2 0 0 2 2 2 1 ROS/MUCR transcriptional regulator protein DUF2379 PF09543.10 KIY72389.1 - 0.0054 16.9 0.6 0.018 15.3 0.6 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF2379) TFA2_Winged_2 PF18121.1 KIY72389.1 - 0.069 12.8 0.7 6.7 6.5 0.1 2.8 2 0 0 2 2 2 0 TFA2 Winged helix domain 2 Acyl-CoA_dh_1 PF00441.24 KIY72389.1 - 0.12 12.6 0.0 0.38 11.0 0.0 1.8 1 1 1 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain REV1_C PF16727.5 KIY72389.1 - 0.64 10.5 4.9 2.5 8.5 0.5 2.9 2 1 0 2 2 2 0 DNA repair protein REV1 C-terminal domain PSII_Pbs27 PF13326.6 KIY72389.1 - 2.2 8.6 9.9 1.1 9.5 6.6 2.2 2 1 0 2 2 2 0 Photosystem II Pbs27 DUF148 PF02520.17 KIY72389.1 - 8.9 6.5 8.4 2.1 8.5 1.5 3.3 3 1 0 3 3 3 0 Domain of unknown function DUF148 p450 PF00067.22 KIY72390.1 - 7.9e-62 209.5 0.0 1.6e-61 208.5 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 FHA PF00498.26 KIY72391.1 - 0.0028 18.0 0.0 0.0045 17.3 0.0 1.4 1 0 0 1 1 1 1 FHA domain CoA_transf_3 PF02515.17 KIY72392.1 - 5.8e-64 216.5 0.0 3.4e-63 214.0 0.0 1.8 1 1 0 1 1 1 1 CoA-transferase family III Acyl-CoA_dh_1 PF00441.24 KIY72393.1 - 2.7e-28 99.1 0.5 4.1e-28 98.5 0.5 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KIY72393.1 - 1.2e-18 67.1 0.1 2.2e-18 66.2 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.28 KIY72393.1 - 3.4e-17 62.4 0.0 9.9e-17 60.9 0.0 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.16 KIY72393.1 - 5.8e-15 55.9 0.0 1.8e-14 54.4 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KIY72393.1 - 2.6e-06 27.7 0.3 4.7e-06 26.9 0.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Fungal_trans PF04082.18 KIY72394.1 - 8.6e-08 31.5 0.7 1.7e-07 30.5 0.7 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY72394.1 - 2.6e-05 24.2 10.4 5.2e-05 23.3 10.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain YhhN PF07947.14 KIY72395.1 - 0.0014 18.3 1.8 0.035 13.7 0.1 2.1 2 0 0 2 2 2 2 YhhN family zf-C2H2 PF00096.26 KIY72396.1 - 5.8e-06 26.5 0.8 0.017 15.5 0.0 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIY72396.1 - 5.4e-05 23.7 1.0 0.12 13.3 0.0 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KIY72396.1 - 0.0036 17.5 0.6 0.051 13.9 0.5 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 KIY72396.1 - 0.076 13.3 1.5 0.42 10.9 1.6 1.9 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 KIY72396.1 - 0.17 12.2 0.8 2.7 8.4 0.7 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Trp_oprn_chp PF09534.10 KIY72398.1 - 0.011 15.6 0.8 0.023 14.5 0.8 1.6 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Rick_17kDa_Anti PF05433.15 KIY72398.1 - 0.026 14.4 0.8 0.055 13.3 0.8 1.4 1 0 0 1 1 1 0 Glycine zipper 2TM domain Gly-zipper_YMGG PF13441.6 KIY72398.1 - 0.03 14.1 0.3 0.062 13.1 0.3 1.4 1 0 0 1 1 1 0 YMGG-like Gly-zipper Mid2 PF04478.12 KIY72398.1 - 0.035 14.0 0.0 0.083 12.7 0.0 1.7 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor YiaAB PF05360.14 KIY72398.1 - 0.051 13.8 0.5 0.095 13.0 0.5 1.4 1 0 0 1 1 1 0 yiaA/B two helix domain XLF PF09302.11 KIY72399.1 - 6.4e-06 26.5 0.1 2.3e-05 24.6 0.1 1.9 1 1 0 1 1 1 1 XLF-Cernunnos, XRcc4-like factor, NHEJ component TOM13 PF08219.11 KIY72400.1 - 5.7e-13 48.7 0.0 1.4e-12 47.4 0.0 1.7 1 0 0 1 1 1 1 Outer membrane protein TOM13 Acetate_kinase PF00871.17 KIY72402.1 - 7.3e-91 304.8 0.0 9.1e-91 304.5 0.0 1.1 1 0 0 1 1 1 1 Acetokinase family XFP_N PF09364.10 KIY72403.1 - 6.8e-147 489.0 0.0 8.7e-147 488.7 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP_C PF09363.10 KIY72403.1 - 2.2e-77 259.1 0.0 4.1e-77 258.2 0.0 1.5 1 0 0 1 1 1 1 XFP C-terminal domain XFP PF03894.15 KIY72403.1 - 9.1e-76 253.5 0.0 1.3e-75 252.9 0.0 1.2 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase TPP_enzyme_C PF02775.21 KIY72403.1 - 0.0092 15.8 0.2 0.021 14.6 0.2 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Abhydrolase_6 PF12697.7 KIY72405.1 - 0.00032 21.4 2.3 0.0011 19.6 0.0 2.4 1 1 0 2 2 2 1 Alpha/beta hydrolase family 6PF2K PF01591.18 KIY72406.1 - 1.1e-66 224.3 0.1 1.6e-66 223.9 0.1 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KIY72406.1 - 7.6e-36 123.6 0.0 1.3e-35 122.8 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 KIY72406.1 - 0.0001 22.5 0.2 0.00022 21.4 0.2 1.6 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 KIY72406.1 - 0.071 13.5 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.25 KIY72407.1 - 3.2e-26 92.3 0.0 4.1e-26 91.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY72407.1 - 2e-11 43.7 0.0 2.6e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIY72407.1 - 1.5e-08 33.8 0.0 2.2e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KIY72407.1 - 0.00077 19.4 0.0 0.45 10.4 0.0 2.4 2 0 0 2 2 2 2 Phosphotransferase enzyme family 2OG-FeII_Oxy_2 PF13532.6 KIY72408.1 - 3.9e-11 43.5 0.0 2.1e-10 41.1 0.0 1.9 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 KIY72408.1 - 0.0012 19.3 0.1 0.0035 17.8 0.1 1.8 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Zn_clus PF00172.18 KIY72409.1 - 6.7e-11 42.1 8.2 9.5e-11 41.6 8.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 KIY72410.1 - 1.1e-32 113.6 36.0 1e-19 70.8 11.2 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KIY72410.1 - 4.4e-14 52.2 76.3 1.8e-13 50.2 43.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DSS1_SEM1 PF05160.13 KIY72411.1 - 5e-22 77.7 6.0 7e-22 77.2 6.0 1.2 1 0 0 1 1 1 1 DSS1/SEM1 family Con-6 PF10346.9 KIY72412.1 - 2.5e-42 142.6 5.9 7.6e-15 54.7 0.2 3.2 3 0 0 3 3 3 3 Conidiation protein 6 SpoIIIAH PF12685.7 KIY72412.1 - 0.0057 16.5 1.4 2.4 7.9 0.1 3.0 2 1 0 3 3 3 2 SpoIIIAH-like protein GATA PF00320.27 KIY72413.1 - 5.7e-08 32.2 7.8 8.3e-08 31.7 7.8 1.3 1 0 0 1 1 1 1 GATA zinc finger Motile_Sperm PF00635.26 KIY72414.1 - 2.8e-27 94.7 0.2 9.8e-27 93.0 0.1 1.9 1 1 1 2 2 2 1 MSP (Major sperm protein) domain REV PF00424.18 KIY72414.1 - 0.013 15.5 0.8 0.03 14.4 0.1 1.9 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) ASH PF15780.5 KIY72414.1 - 0.02 15.1 0.1 0.043 14.0 0.1 1.5 1 0 0 1 1 1 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin FixG_C PF11614.8 KIY72414.1 - 0.049 13.8 0.0 0.092 13.0 0.0 1.4 1 0 0 1 1 1 0 IG-like fold at C-terminal of FixG, putative oxidoreductase FXR_C1 PF16096.5 KIY72414.1 - 1.6 9.0 5.5 0.33 11.2 0.8 2.2 3 0 0 3 3 3 0 Fragile X-related 1 protein C-terminal region 2 Lipase_GDSL_2 PF13472.6 KIY72415.1 - 2.6e-05 24.7 0.8 0.0001 22.8 0.8 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Ank_4 PF13637.6 KIY72417.1 - 1e-10 41.9 0.2 3.9e-05 24.1 0.2 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KIY72417.1 - 3.7e-07 30.3 0.2 1e-06 28.9 0.2 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KIY72417.1 - 2.4e-05 24.8 0.0 5.6e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KIY72417.1 - 0.0025 18.2 0.1 0.0068 16.8 0.1 1.8 1 0 0 1 1 1 1 Ankyrin repeat Ank_3 PF13606.6 KIY72417.1 - 0.017 15.6 0.0 0.098 13.3 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeat Methyltransf_25 PF13649.6 KIY72417.1 - 0.11 13.2 0.0 0.5 11.1 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain MFS_1 PF07690.16 KIY72418.1 - 6.2e-38 130.6 22.2 6.2e-38 130.6 22.2 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KIY72418.1 - 9.8e-05 21.8 2.4 9.8e-05 21.8 2.4 1.6 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 KIY72418.1 - 0.061 11.6 1.3 0.078 11.3 0.0 1.9 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Oxidored_FMN PF00724.20 KIY72419.1 - 1.1e-100 337.3 0.0 1.2e-100 337.1 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family ABC_membrane PF00664.23 KIY72420.1 - 4.9e-105 351.1 27.8 1.7e-52 178.7 5.4 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KIY72420.1 - 5.2e-68 227.8 0.0 5.7e-33 114.3 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KIY72420.1 - 1e-11 44.7 5.8 9e-05 22.0 0.1 4.2 2 2 0 4 4 4 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 KIY72420.1 - 3.3e-07 29.5 1.3 0.009 14.8 0.1 2.8 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_21 PF13304.6 KIY72420.1 - 1.4e-06 28.4 0.4 0.15 11.9 0.0 3.9 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KIY72420.1 - 2.1e-06 27.4 0.2 0.031 14.0 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.6 KIY72420.1 - 5e-06 26.5 0.2 0.022 14.5 0.0 2.8 3 0 0 3 3 3 2 AAA ATPase domain AAA_16 PF13191.6 KIY72420.1 - 1.9e-05 25.1 5.3 0.01 16.3 0.1 3.4 2 1 1 3 3 3 2 AAA ATPase domain RsgA_GTPase PF03193.16 KIY72420.1 - 5.2e-05 23.2 0.0 0.48 10.3 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 KIY72420.1 - 0.00011 22.4 3.3 0.27 11.5 0.1 3.8 3 2 0 3 3 2 2 AAA domain Zeta_toxin PF06414.12 KIY72420.1 - 0.00015 21.1 0.0 0.2 10.9 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin AAA_25 PF13481.6 KIY72420.1 - 0.0005 19.7 1.0 1.1 8.7 0.0 3.6 3 0 0 3 3 3 1 AAA domain G-alpha PF00503.20 KIY72420.1 - 0.00064 19.0 0.0 0.65 9.1 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit AAA_30 PF13604.6 KIY72420.1 - 0.0018 18.1 4.6 0.47 10.2 0.0 3.5 3 2 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.23 KIY72420.1 - 0.0034 17.4 0.3 3.9 7.6 0.0 3.6 4 0 0 4 4 3 1 50S ribosome-binding GTPase AAA_7 PF12775.7 KIY72420.1 - 0.0038 16.8 0.0 0.79 9.2 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_28 PF13521.6 KIY72420.1 - 0.0078 16.5 0.2 2.3 8.4 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KIY72420.1 - 0.0084 16.7 0.0 1.8 9.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KIY72420.1 - 0.011 15.8 0.0 1.7 8.7 0.0 3.2 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA PF00004.29 KIY72420.1 - 0.012 16.0 2.0 2.9 8.3 0.2 3.8 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KIY72420.1 - 0.014 15.6 0.0 7.7 6.7 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KIY72420.1 - 0.016 15.8 2.7 6.4 7.2 0.0 3.3 3 0 0 3 3 3 0 AAA domain PRK PF00485.18 KIY72420.1 - 0.023 14.4 0.0 1.1 9.0 0.0 2.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Rad17 PF03215.15 KIY72420.1 - 0.03 14.3 0.0 0.39 10.6 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain Viral_helicase1 PF01443.18 KIY72420.1 - 0.059 13.1 0.0 5.5 6.7 0.0 2.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.22 KIY72420.1 - 0.074 13.4 0.0 5.7 7.4 0.0 2.8 2 0 0 2 2 2 0 RNA helicase NB-ARC PF00931.22 KIY72420.1 - 0.086 12.0 0.0 1.4 8.0 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain DUF815 PF05673.13 KIY72420.1 - 0.093 11.9 0.0 5.3 6.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_17 PF13207.6 KIY72420.1 - 0.18 12.2 0.5 34 4.9 0.0 3.0 3 0 0 3 3 2 0 AAA domain DUF87 PF01935.17 KIY72420.1 - 0.23 11.5 4.5 6 6.9 0.1 4.0 6 0 0 6 6 4 0 Helicase HerA, central domain SbcCD_C PF13558.6 KIY72420.1 - 0.4 10.9 2.8 40 4.5 0.1 3.5 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit MFS_1 PF07690.16 KIY72421.1 - 2.8e-39 135.1 40.9 2.8e-39 135.1 40.9 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIY72421.1 - 1.2e-15 57.4 7.1 1.2e-15 57.4 7.1 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KIY72421.1 - 2.1e-10 39.7 3.8 3.8e-10 38.8 3.8 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 KIY72421.1 - 9.5e-09 35.0 7.6 9.5e-09 35.0 7.6 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Wzz PF02706.15 KIY72421.1 - 0.11 12.8 0.5 1.3 9.3 0.0 2.8 3 0 0 3 3 3 0 Chain length determinant protein DDDD PF10161.9 KIY72421.1 - 0.12 12.2 0.3 0.87 9.4 0.0 2.4 2 0 0 2 2 2 0 Putative mitochondrial precursor protein Pkinase PF00069.25 KIY72422.1 - 1.4e-69 234.4 0.0 1.8e-69 234.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY72422.1 - 2e-32 112.5 0.0 2.8e-32 112.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 KIY72422.1 - 3.2e-08 34.1 7.2 7.5e-08 33.0 7.2 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 KIY72422.1 - 7.3e-08 31.7 0.1 1e-07 31.3 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KIY72422.1 - 6.1e-05 22.5 0.0 0.00016 21.1 0.0 1.6 1 1 1 2 2 2 1 Kinase-like FTA2 PF13095.6 KIY72422.1 - 0.0038 16.9 0.1 1.2 8.7 0.0 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KIY72422.1 - 0.0082 15.5 0.1 0.014 14.7 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIY72422.1 - 0.1 12.5 0.3 0.24 11.3 0.3 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family CRAL_TRIO PF00650.20 KIY72423.1 - 2.2e-29 102.2 0.0 3e-29 101.8 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KIY72423.1 - 1.1e-13 51.1 2.1 1.2e-13 51.0 0.2 2.1 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KIY72423.1 - 0.011 15.9 0.0 0.017 15.3 0.0 1.3 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain BUD22 PF09073.10 KIY72424.1 - 0.019 14.3 9.0 0.027 13.8 9.0 1.1 1 0 0 1 1 1 0 BUD22 RRN3 PF05327.11 KIY72424.1 - 0.064 11.8 1.6 0.088 11.3 1.6 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SAPS PF04499.15 KIY72424.1 - 0.082 11.7 1.4 0.11 11.2 1.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein ORC6 PF05460.13 KIY72424.1 - 0.18 11.0 3.6 0.29 10.4 3.6 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) RPN2_C PF18004.1 KIY72424.1 - 0.31 10.9 5.8 0.62 10.0 5.8 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Nop14 PF04147.12 KIY72424.1 - 0.39 8.9 12.2 0.53 8.4 12.2 1.1 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 KIY72424.1 - 0.53 9.5 11.3 0.76 9.0 11.3 1.1 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.14 KIY72424.1 - 0.63 8.3 8.7 0.85 7.8 8.7 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 KIY72424.1 - 0.88 8.9 11.7 1.2 8.5 11.7 1.1 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 KIY72424.1 - 1.2 7.1 15.7 1.9 6.5 15.7 1.2 1 0 0 1 1 1 0 DNA polymerase phi SGT1 PF07093.11 KIY72424.1 - 1.4 7.2 10.3 2.1 6.7 10.3 1.1 1 0 0 1 1 1 0 SGT1 protein DUF4820 PF16091.5 KIY72424.1 - 1.9 7.8 5.2 3 7.2 5.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) YL1 PF05764.13 KIY72424.1 - 2.1 8.4 14.7 3.2 7.8 14.7 1.2 1 0 0 1 1 1 0 YL1 nuclear protein TRAP_alpha PF03896.16 KIY72424.1 - 2.7 7.1 7.0 4.4 6.4 7.0 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit PPP4R2 PF09184.11 KIY72424.1 - 5.1 6.6 16.5 7.6 6.0 16.5 1.1 1 0 0 1 1 1 0 PPP4R2 RSN1_7TM PF02714.15 KIY72425.1 - 1.3e-41 142.8 16.4 1.3e-41 142.8 16.4 1.8 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 KIY72425.1 - 2.1e-21 76.9 0.0 4.8e-16 59.5 0.0 2.8 2 1 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 KIY72425.1 - 9e-18 64.5 1.6 9e-18 64.5 1.6 2.3 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport ETC_C1_NDUFA4 PF04800.12 KIY72426.1 - 4.2e-35 119.9 0.0 4.7e-35 119.7 0.0 1.0 1 0 0 1 1 1 1 ETC complex I subunit conserved region F-box-like PF12937.7 KIY72427.1 - 0.00064 19.6 0.1 0.0018 18.1 0.1 1.8 1 0 0 1 1 1 1 F-box-like IMPa_N_2 PF18650.1 KIY72427.1 - 0.17 11.1 0.0 5.1 6.3 0.0 2.1 2 0 0 2 2 2 0 Immunomodulating metalloprotease N-terminal domain Gln-synt_C PF00120.24 KIY72428.1 - 2.9e-64 217.2 0.0 3.9e-64 216.8 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N_2 PF16952.5 KIY72428.1 - 0.003 17.4 0.0 0.0075 16.1 0.0 1.6 1 0 0 1 1 1 1 Glutamine synthetase N-terminal domain F-box-like PF12937.7 KIY72429.1 - 0.069 13.1 0.2 0.21 11.5 0.0 1.9 2 0 0 2 2 2 0 F-box-like ICMT PF04140.14 KIY72431.1 - 7.3e-12 45.5 0.7 2.4e-11 43.9 0.2 2.0 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KIY72431.1 - 1.4e-10 41.5 3.5 6.5e-10 39.4 0.9 2.3 1 1 1 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 KIY72431.1 - 2.1e-06 26.8 0.1 2.6e-06 26.5 0.1 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Tetraspanin PF00335.20 KIY72431.1 - 0.045 13.5 0.5 0.079 12.7 0.5 1.3 1 0 0 1 1 1 0 Tetraspanin family zf-H2C2_2 PF13465.6 KIY72433.1 - 0.0041 17.5 6.5 0.0041 17.5 6.5 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KIY72433.1 - 0.22 12.5 0.3 0.22 12.5 0.3 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger MR_MLE_C PF13378.6 KIY72434.1 - 2.3e-42 145.1 0.0 3.1e-42 144.6 0.0 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KIY72434.1 - 1e-09 38.6 0.0 1.6e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain zf-C2H2 PF00096.26 KIY72435.1 - 9.3e-06 25.8 9.1 0.0017 18.7 0.6 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIY72435.1 - 0.024 15.5 6.0 0.3 12.1 0.1 3.2 2 0 0 2 2 2 0 C2H2-type zinc finger FOXP-CC PF16159.5 KIY72435.1 - 0.69 10.6 7.1 0.88 10.2 2.7 2.3 1 1 1 2 2 2 0 FOXP coiled-coil domain Cation_efflux PF01545.21 KIY72436.1 - 5.6e-18 65.4 8.2 6.8e-18 65.1 8.2 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KIY72436.1 - 7.3e-13 48.5 0.2 1.2e-12 47.8 0.2 1.3 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter zf-C2H2 PF00096.26 KIY72437.1 - 9.4e-14 51.0 11.1 5.2e-05 23.5 0.2 3.3 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIY72437.1 - 2e-10 40.6 10.9 0.0045 17.7 0.1 3.3 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KIY72437.1 - 2.3e-10 40.4 11.9 1.5e-05 25.2 0.2 4.2 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KIY72437.1 - 7.7e-05 22.9 8.5 0.0039 17.4 0.0 3.3 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KIY72437.1 - 0.00023 21.5 7.7 0.0083 16.5 0.1 3.3 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2HE PF16278.5 KIY72437.1 - 0.00038 20.8 4.2 0.043 14.3 2.3 2.4 2 1 0 2 2 2 1 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_aberr PF17017.5 KIY72437.1 - 0.00041 20.5 2.3 0.8 9.8 0.0 3.0 1 1 2 3 3 3 2 Aberrant zinc-finger zf-C2H2_8 PF15909.5 KIY72437.1 - 0.00049 20.3 3.5 0.0012 19.1 2.4 1.9 1 1 1 2 2 2 1 C2H2-type zinc ribbon FOXP-CC PF16159.5 KIY72437.1 - 0.00064 20.3 8.1 0.043 14.5 5.0 2.8 1 1 1 2 2 2 1 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 KIY72437.1 - 0.0028 17.6 3.6 0.088 12.8 0.4 3.2 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KIY72437.1 - 0.028 14.8 2.6 0.82 10.0 1.3 2.4 1 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) IBR PF01485.21 KIY72437.1 - 0.076 13.2 7.6 0.48 10.7 4.3 2.2 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain Rep_fac-A_C PF08646.10 KIY72437.1 - 0.14 11.9 0.6 0.21 11.3 0.6 1.2 1 0 0 1 1 1 0 Replication factor-A C terminal domain zf-LYAR PF08790.11 KIY72437.1 - 1.4 8.9 6.0 6.6 6.7 0.1 3.4 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger F-box-like PF12937.7 KIY72438.1 - 0.0036 17.1 0.1 0.013 15.4 0.1 2.0 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KIY72438.1 - 0.047 13.6 0.3 0.14 12.0 0.0 1.9 2 0 0 2 2 2 0 F-box VSP PF03302.13 KIY72440.1 - 2.9e-05 23.1 6.3 3.9e-05 22.7 6.3 1.1 1 0 0 1 1 1 1 Giardia variant-specific surface protein Mucin PF01456.17 KIY72440.1 - 0.0015 18.5 33.9 0.0015 18.5 33.9 2.5 2 1 1 3 3 3 1 Mucin-like glycoprotein Podoplanin PF05808.11 KIY72440.1 - 0.016 15.3 8.9 0.016 15.3 8.9 2.2 1 1 1 2 2 2 0 Podoplanin CD99L2 PF12301.8 KIY72440.1 - 0.13 12.5 11.5 0.34 11.2 11.4 1.7 1 1 0 1 1 1 0 CD99 antigen like protein 2 Anophelin PF10731.9 KIY72440.1 - 0.15 11.9 5.4 0.18 11.7 0.1 2.6 2 0 0 2 2 2 0 Thrombin inhibitor from mosquito Utp14 PF04615.13 KIY72440.1 - 9.5 4.6 14.5 12 4.3 14.5 1.0 1 0 0 1 1 1 0 Utp14 protein Pkinase PF00069.25 KIY72442.1 - 1.8e-25 89.8 0.0 3e-25 89.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY72442.1 - 4.4e-13 49.1 0.0 6.2e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KIY72442.1 - 0.0014 18.0 0.0 0.0024 17.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KIY72442.1 - 0.0064 15.8 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 KIY72442.1 - 0.063 12.3 0.0 0.094 11.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.22 KIY72442.1 - 0.098 12.2 0.1 0.19 11.3 0.1 1.4 1 0 0 1 1 1 0 RIO1 family Fungal_trans PF04082.18 KIY72443.1 - 1.1e-21 77.1 0.0 2.3e-21 76.0 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY72443.1 - 4.3e-07 30.0 10.6 9.4e-07 28.9 10.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ATG16 PF08614.11 KIY72443.1 - 0.062 13.5 0.1 0.13 12.4 0.1 1.5 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) zf-C2H2 PF00096.26 KIY72444.1 - 5.9e-07 29.6 5.3 0.0096 16.3 0.2 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIY72444.1 - 6.6e-05 23.4 5.4 0.069 14.0 0.2 2.7 2 1 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KIY72444.1 - 6.6e-05 23.2 1.9 0.00031 21.0 0.3 2.4 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_11 PF16622.5 KIY72444.1 - 0.00034 20.3 0.5 0.94 9.3 0.0 2.4 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-Di19 PF05605.12 KIY72444.1 - 0.00082 19.6 0.1 0.0015 18.7 0.1 1.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-BED PF02892.15 KIY72444.1 - 0.0016 18.4 0.5 0.14 12.2 0.0 2.4 2 0 0 2 2 2 1 BED zinc finger zf-met PF12874.7 KIY72444.1 - 0.0036 17.6 0.2 0.64 10.5 0.1 2.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KIY72444.1 - 0.0061 16.8 0.1 0.59 10.5 0.0 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KIY72444.1 - 0.0065 16.2 2.2 0.069 12.9 1.1 2.3 2 0 0 2 2 2 1 C2H2-type zinc-finger domain DUF629 PF04780.12 KIY72444.1 - 0.074 11.6 0.1 0.09 11.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF629) zf-FPG_IleRS PF06827.14 KIY72444.1 - 0.14 12.0 1.7 0.17 11.8 0.4 1.8 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS Melibiase_2 PF16499.5 KIY72445.1 - 3.3e-13 49.5 4.2 1.4e-09 37.5 3.7 2.1 1 1 1 2 2 2 2 Alpha galactosidase A Melibiase_C PF17801.1 KIY72445.1 - 4.2e-08 33.1 0.1 7.7e-08 32.3 0.1 1.5 1 0 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain Glyco_hydro_97 PF10566.9 KIY72445.1 - 0.00075 18.9 0.0 0.0047 16.3 0.0 2.0 1 1 0 1 1 1 1 Glycoside hydrolase 97 RebB PF11747.8 KIY72447.1 - 1.4 9.0 4.2 19 5.5 3.8 2.4 2 0 0 2 2 2 0 Killing trait zf-C2H2 PF00096.26 KIY72448.1 - 7.8e-08 32.4 5.7 0.00021 21.6 0.9 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIY72448.1 - 9.4e-05 22.9 5.0 0.0049 17.6 0.8 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KIY72448.1 - 0.0029 17.9 2.9 0.0029 17.9 2.9 2.2 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KIY72448.1 - 0.0085 16.4 0.8 0.046 14.0 0.1 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 KIY72448.1 - 0.042 14.1 4.3 0.088 13.1 0.4 2.4 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Ntox30 PF15532.6 KIY72449.1 - 0.13 12.7 0.1 0.25 11.7 0.1 1.5 1 1 0 1 1 1 0 Bacterial toxin 30 Fungal_trans PF04082.18 KIY72450.1 - 1.4e-22 80.0 0.0 2.1e-22 79.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY72451.1 - 6.3e-08 32.6 6.5 8.8e-08 32.1 6.5 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.12 KIY72451.1 - 0.96 10.0 9.1 3.9 8.0 8.3 1.9 1 1 1 2 2 2 0 Dickkopf N-terminal cysteine-rich region TFIIF_beta PF02270.15 KIY72452.1 - 1.7e-23 82.5 0.3 2.7e-23 81.9 0.3 1.3 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain TFIIF_beta_N PF17683.1 KIY72452.1 - 2.1e-21 77.0 0.0 4.1e-21 76.1 0.0 1.5 1 0 0 1 1 1 1 TFIIF, beta subunit N-terminus Tau95 PF09734.9 KIY72452.1 - 0.0033 18.2 0.3 0.0059 17.4 0.3 1.5 1 1 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Ala_racemase_N PF01168.20 KIY72453.1 - 1.2e-16 61.1 0.0 3.1e-16 59.7 0.0 1.6 1 1 0 1 1 1 1 Alanine racemase, N-terminal domain Band_7 PF01145.25 KIY72454.1 - 0.00013 22.0 0.8 0.00013 22.0 0.8 3.0 2 1 0 2 2 2 1 SPFH domain / Band 7 family Peptidase_M35 PF02102.15 KIY72455.1 - 1.2e-38 133.0 19.9 1.5e-38 132.6 19.9 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 KIY72455.1 - 1.2e-21 77.8 3.6 2.1e-21 77.0 3.6 1.4 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase HRXXH PF13933.6 KIY72455.1 - 1.7e-07 31.1 5.4 3.5e-07 30.0 5.4 1.5 1 1 0 1 1 1 1 Putative peptidase family ADH_zinc_N_2 PF13602.6 KIY72455.1 - 0.027 15.5 0.2 0.054 14.5 0.2 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase CARDB PF07705.11 KIY72455.1 - 0.18 12.1 5.0 0.68 10.2 0.1 3.1 3 1 0 3 3 3 0 CARDB Abhydrolase_1 PF00561.20 KIY72456.1 - 7.8e-24 84.7 0.0 5e-23 82.1 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 KIY72456.1 - 3.2e-23 81.8 0.0 5.3e-23 81.1 0.0 1.3 1 0 0 1 1 1 1 TAP-like protein Hydrolase_4 PF12146.8 KIY72456.1 - 0.025 13.9 0.0 3.1 7.0 0.0 2.5 3 0 0 3 3 3 0 Serine aminopeptidase, S33 DUF2415 PF10313.9 KIY72457.1 - 5.2e-06 26.3 0.0 2e-05 24.4 0.0 2.0 2 0 0 2 2 2 1 Uncharacterised protein domain (DUF2415) Ge1_WD40 PF16529.5 KIY72457.1 - 0.0039 16.2 0.2 0.097 11.6 0.1 2.3 2 1 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 KIY72457.1 - 0.022 15.1 0.1 2.5 8.5 0.0 3.5 3 1 2 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KIY72457.1 - 0.056 14.3 8.4 25 5.9 0.0 6.1 5 2 0 5 5 5 0 WD domain, G-beta repeat PD40 PF07676.12 KIY72457.1 - 1 9.4 5.9 36 4.5 0.0 4.6 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Macoilin PF09726.9 KIY72458.1 - 0.00058 18.6 11.4 0.0011 17.7 11.4 1.4 1 0 0 1 1 1 1 Macoilin family TMF_DNA_bd PF12329.8 KIY72458.1 - 0.013 15.5 1.0 0.013 15.5 1.0 4.2 2 2 1 4 4 4 0 TATA element modulatory factor 1 DNA binding Spc7 PF08317.11 KIY72458.1 - 0.016 14.1 26.8 0.045 12.6 10.6 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein Pox_A_type_inc PF04508.12 KIY72458.1 - 0.037 13.9 1.1 0.099 12.5 0.1 2.3 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat FUSC PF04632.12 KIY72458.1 - 0.06 11.9 14.2 0.1 11.1 14.2 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Fez1 PF06818.15 KIY72458.1 - 0.092 13.2 24.5 0.022 15.2 20.3 2.0 1 1 1 2 2 2 0 Fez1 DUF3450 PF11932.8 KIY72458.1 - 1.5 8.1 27.8 1.8 7.8 14.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF1826 PF08856.11 KIY72458.1 - 1.9 8.4 6.1 1.6 8.6 4.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1826) CALCOCO1 PF07888.11 KIY72458.1 - 1.9 7.3 28.9 3.8 6.3 28.9 1.4 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like SKN1 PF03935.15 KIY72459.1 - 5.8e-189 628.7 2.2 6.7e-189 628.5 2.2 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) ABC2_membrane PF01061.24 KIY72460.1 - 1.8e-32 112.5 19.1 1.8e-32 112.5 19.1 1.7 2 0 0 2 2 1 1 ABC-2 type transporter ABC_tran PF00005.27 KIY72460.1 - 1.8e-26 93.3 0.1 2.9e-26 92.6 0.1 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KIY72460.1 - 4.5e-05 23.4 0.7 0.17 11.7 0.2 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KIY72460.1 - 0.0006 19.5 0.1 0.0014 18.3 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KIY72460.1 - 0.00063 19.7 0.1 0.0012 18.8 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase Rad17 PF03215.15 KIY72460.1 - 0.0029 17.5 0.0 0.0048 16.8 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain EGF_2 PF07974.13 KIY72460.1 - 0.017 15.5 13.8 0.017 15.5 13.8 4.0 4 0 0 4 4 3 0 EGF-like domain AAA_16 PF13191.6 KIY72460.1 - 0.02 15.3 0.1 0.046 14.1 0.0 1.6 2 0 0 2 2 1 0 AAA ATPase domain AAA_28 PF13521.6 KIY72460.1 - 0.026 14.8 0.1 0.044 14.0 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KIY72460.1 - 0.028 15.0 0.0 0.2 12.2 0.1 2.1 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KIY72460.1 - 0.042 14.0 0.0 0.073 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain Calici_MSP PF05752.11 KIY72460.1 - 0.054 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Calicivirus minor structural protein AAA_22 PF13401.6 KIY72460.1 - 0.072 13.4 0.1 0.16 12.2 0.1 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KIY72460.1 - 0.089 12.9 0.1 0.17 12.0 0.1 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase SMC_N PF02463.19 KIY72460.1 - 0.15 11.5 0.1 0.41 10.0 0.1 1.6 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_24 PF13479.6 KIY72460.1 - 0.2 11.3 0.0 0.38 10.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC2_membrane_3 PF12698.7 KIY72460.1 - 1.7 7.7 25.7 0.25 10.4 20.4 2.0 1 1 1 2 2 2 0 ABC-2 family transporter protein Laminin_EGF PF00053.24 KIY72460.1 - 5 7.4 30.6 0.35 11.0 6.2 3.6 2 2 1 3 3 2 0 Laminin EGF domain Epimerase PF01370.21 KIY72461.1 - 3e-19 69.4 0.0 6.2e-19 68.4 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KIY72461.1 - 3.3e-12 46.7 0.1 6.5e-12 45.7 0.1 1.5 1 1 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KIY72461.1 - 1.2e-09 37.5 0.0 2.5e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KIY72461.1 - 1.4e-08 34.2 0.0 1.1e-06 28.0 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 KIY72461.1 - 5.8e-07 29.2 0.0 8e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KIY72461.1 - 0.0037 16.8 0.2 0.0077 15.8 0.2 1.5 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 KIY72461.1 - 0.078 12.4 0.1 0.18 11.2 0.1 1.7 1 0 0 1 1 1 0 short chain dehydrogenase F-box PF00646.33 KIY72462.1 - 3.1e-10 39.6 2.3 1e-09 38.0 2.3 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KIY72462.1 - 3.1e-08 33.4 0.6 9.4e-08 31.8 0.6 1.9 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KIY72462.1 - 0.013 15.4 0.2 0.031 14.2 0.2 1.6 1 0 0 1 1 1 0 F-box Glyco_transf_22 PF03901.17 KIY72463.1 - 3.5e-38 131.9 14.5 4.3e-38 131.6 14.5 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Pkinase PF00069.25 KIY72464.1 - 8.1e-51 172.9 0.0 1.9e-48 165.2 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY72464.1 - 7.4e-31 107.4 2.1 1.9e-20 73.3 0.0 3.2 2 1 1 3 3 3 3 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIY72464.1 - 2.6e-06 26.5 0.1 7.2e-06 25.0 0.0 1.6 1 1 1 2 2 2 1 Fungal protein kinase APH PF01636.23 KIY72464.1 - 1.6e-05 25.0 0.2 0.0011 18.9 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 KIY72464.1 - 2.5e-05 23.9 0.4 3.8e-05 23.4 0.4 1.2 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 KIY72464.1 - 0.00026 20.4 0.1 0.54 9.5 0.0 2.5 3 0 0 3 3 3 2 Kinase-like PGBA_N PF15436.6 KIY72464.1 - 0.04 13.5 0.0 0.068 12.8 0.0 1.3 1 0 0 1 1 1 0 Plasminogen-binding protein pgbA N-terminal FTA2 PF13095.6 KIY72464.1 - 0.11 12.1 0.2 0.49 10.0 0.1 1.8 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Aminotran_1_2 PF00155.21 KIY72465.1 - 7.1e-22 78.1 0.0 3.1e-21 76.0 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 KIY72465.1 - 1.3e-06 27.5 0.0 1.1e-05 24.4 0.0 1.9 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase NmrA PF05368.13 KIY72466.1 - 5e-10 39.3 0.5 1.5e-09 37.8 0.3 1.7 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 KIY72466.1 - 9.1e-10 38.7 0.9 2.2e-09 37.5 0.4 1.9 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 KIY72466.1 - 1e-07 31.7 0.1 0.002 17.6 0.1 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KIY72466.1 - 4e-07 30.3 0.4 7.6e-07 29.4 0.4 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 KIY72466.1 - 2.6e-05 24.5 1.5 4e-05 23.9 0.6 1.8 2 0 0 2 2 2 1 TrkA-N domain GDP_Man_Dehyd PF16363.5 KIY72466.1 - 0.00013 21.5 0.1 0.24 10.7 0.2 2.7 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KIY72466.1 - 0.00017 20.7 1.7 0.0016 17.5 0.2 2.6 2 1 1 3 3 3 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 KIY72466.1 - 0.00033 21.1 0.0 0.00061 20.2 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KIY72466.1 - 0.00072 19.6 0.1 0.0013 18.8 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 KIY72466.1 - 0.0012 19.4 0.2 0.0026 18.3 0.2 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.15 KIY72466.1 - 0.0032 16.6 0.1 0.0046 16.1 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 KIY72466.1 - 0.0066 15.6 0.5 0.017 14.3 0.1 1.9 2 0 0 2 2 2 1 Male sterility protein KR PF08659.10 KIY72466.1 - 0.008 16.1 0.1 0.013 15.4 0.1 1.4 1 0 0 1 1 1 1 KR domain DapB_N PF01113.20 KIY72466.1 - 0.024 14.8 0.2 0.024 14.8 0.2 1.9 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus zf-CRD PF17979.1 KIY72468.1 - 8.4e-11 42.2 0.6 8.4e-11 42.2 0.6 2.6 3 0 0 3 3 3 1 Cysteine rich domain with multizinc binding regions zf-C3HC4_2 PF13923.6 KIY72468.1 - 2.6e-06 27.2 11.7 2.6e-06 27.2 11.7 3.5 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIY72468.1 - 9.7e-06 25.8 12.2 9.7e-06 25.8 12.2 3.7 4 0 0 4 4 4 1 Ring finger domain zf-C3HC4_3 PF13920.6 KIY72468.1 - 0.00036 20.3 10.4 0.00036 20.3 10.4 3.7 4 0 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIY72468.1 - 0.0035 17.2 10.3 0.0035 17.2 10.3 4.1 4 0 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) Zn_clus PF00172.18 KIY72469.1 - 4.4e-09 36.3 10.6 1e-08 35.1 10.6 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain XRN1_DBM PF18245.1 KIY72470.1 - 0.025 14.5 3.5 0.075 13.0 3.5 1.9 1 0 0 1 1 1 0 5-3 exonuclease XRN1 DCP1-binding motif IGR PF09597.10 KIY72471.1 - 4.2e-17 62.0 0.1 7.9e-17 61.1 0.1 1.5 1 0 0 1 1 1 1 IGR protein motif Mito_carr PF00153.27 KIY72472.1 - 2e-44 149.4 14.3 2.1e-16 59.6 0.5 4.7 2 2 2 4 4 4 4 Mitochondrial carrier protein Serine_protease PF18405.1 KIY72472.1 - 0.00064 19.0 5.0 0.28 10.3 0.2 3.1 2 1 1 3 3 3 2 Gammaproteobacterial serine protease YtxH PF12732.7 KIY72472.1 - 0.17 12.4 2.3 7.3 7.2 0.1 2.5 2 0 0 2 2 2 0 YtxH-like protein NTP_transf_9 PF04248.12 KIY72474.1 - 9.7e-32 108.7 0.1 1.1e-31 108.6 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF427) RIBIOP_C PF04950.12 KIY72475.1 - 1.1e-94 317.2 0.0 1.1e-94 317.2 0.0 2.0 2 0 0 2 2 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 KIY72475.1 - 6.5e-29 99.9 0.7 1.4e-28 98.8 0.0 2.0 2 0 0 2 2 1 1 AARP2CN (NUC121) domain AAA_16 PF13191.6 KIY72475.1 - 1e-05 26.0 0.2 5.2e-05 23.7 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain Rtf2 PF04641.12 KIY72475.1 - 2.3e-05 23.9 5.3 2.3e-05 23.9 5.3 2.9 4 0 0 4 4 1 1 Rtf2 RING-finger AAA_22 PF13401.6 KIY72475.1 - 4.7e-05 23.7 0.0 0.00014 22.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 KIY72475.1 - 0.00038 21.0 1.3 0.0012 19.4 0.0 2.4 2 0 0 2 2 2 1 ABC transporter AAA_33 PF13671.6 KIY72475.1 - 0.00045 20.4 0.0 0.00045 20.4 0.0 2.7 3 0 0 3 3 2 1 AAA domain GTP_EFTU PF00009.27 KIY72475.1 - 0.0008 19.0 0.0 0.3 10.6 0.0 2.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA PF00004.29 KIY72475.1 - 0.00092 19.6 0.2 0.0025 18.3 0.1 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 KIY72475.1 - 0.0013 18.8 0.1 0.0044 17.1 0.1 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase NACHT PF05729.12 KIY72475.1 - 0.0024 17.8 0.1 0.0051 16.7 0.1 1.5 1 0 0 1 1 1 1 NACHT domain PduV-EutP PF10662.9 KIY72475.1 - 0.0035 17.1 0.1 0.0096 15.7 0.1 1.7 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation NB-ARC PF00931.22 KIY72475.1 - 0.0045 16.2 0.0 0.0085 15.3 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_30 PF13604.6 KIY72475.1 - 0.0048 16.6 0.1 0.011 15.5 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KIY72475.1 - 0.0055 17.0 0.0 0.016 15.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KIY72475.1 - 0.0058 17.0 0.0 0.016 15.6 0.0 1.7 1 0 0 1 1 1 1 RNA helicase MobB PF03205.14 KIY72475.1 - 0.0073 16.2 0.2 0.26 11.2 0.1 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.6 KIY72475.1 - 0.0092 16.5 0.1 0.0092 16.5 0.1 2.9 3 0 0 3 3 1 1 AAA domain cobW PF02492.19 KIY72475.1 - 0.016 14.8 0.1 0.034 13.7 0.1 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 KIY72475.1 - 0.017 14.8 0.0 0.055 13.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KIY72475.1 - 0.022 15.1 0.1 0.053 13.9 0.1 1.6 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 KIY72475.1 - 0.027 14.7 0.0 0.062 13.5 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_14 PF13173.6 KIY72475.1 - 0.035 14.2 0.0 0.12 12.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KIY72475.1 - 0.04 13.5 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KIY72475.1 - 0.042 13.8 0.4 0.081 12.8 0.4 1.5 1 0 0 1 1 1 0 NTPase RsgA_GTPase PF03193.16 KIY72475.1 - 0.046 13.6 0.0 0.21 11.5 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase AAA_5 PF07728.14 KIY72475.1 - 0.051 13.6 0.1 0.11 12.5 0.1 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.6 KIY72475.1 - 0.055 13.9 0.1 0.055 13.9 0.1 3.4 3 0 0 3 3 2 0 AAA domain SRP54 PF00448.22 KIY72475.1 - 4.5 6.8 6.5 0.15 11.7 0.2 1.7 2 0 0 2 2 1 0 SRP54-type protein, GTPase domain Cep57_MT_bd PF06657.13 KIY72476.1 - 8.4e-21 74.2 0.0 8.4e-21 74.2 0.0 4.6 4 1 0 4 4 4 1 Centrosome microtubule-binding domain of Cep57 Cep57_CLD_2 PF14197.6 KIY72476.1 - 6.7e-10 38.9 11.6 6.7e-10 38.9 11.6 4.4 4 1 0 4 4 4 1 Centrosome localisation domain of PPC89 TetR_C_24 PF17932.1 KIY72476.1 - 0.045 14.0 1.5 0.23 11.7 1.5 2.4 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain IZUMO PF15005.6 KIY72476.1 - 0.29 11.7 8.4 0.078 13.5 4.4 2.2 2 0 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated DUF3512 PF12024.8 KIY72477.1 - 0.0093 15.5 0.0 0.012 15.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3512) Ctr PF04145.15 KIY72478.1 - 1.7e-28 100.1 8.9 4.4e-28 98.8 8.9 1.6 1 1 0 1 1 1 1 Ctr copper transporter family CPBP PF02517.16 KIY72478.1 - 0.026 14.9 0.7 0.026 14.9 0.7 2.2 2 0 0 2 2 2 0 CPBP intramembrane metalloprotease Ferric_reduct PF01794.19 KIY72479.1 - 2.2e-14 53.6 8.5 2.2e-14 53.6 8.5 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KIY72479.1 - 2.6e-13 50.0 0.0 4.8e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 KIY72479.1 - 3e-07 30.7 0.0 9.6e-07 29.0 0.0 1.8 2 0 0 2 2 2 1 Ferric reductase NAD binding domain DNA_methylase PF00145.17 KIY72480.1 - 5.7e-32 111.4 0.0 4.3e-27 95.3 0.0 3.2 2 1 0 2 2 2 2 C-5 cytosine-specific DNA methylase BAH PF01426.18 KIY72480.1 - 3.8e-08 33.2 0.2 0.011 15.6 0.0 3.1 3 0 0 3 3 3 2 BAH domain Met_10 PF02475.16 KIY72480.1 - 0.049 13.4 0.0 0.094 12.5 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein SRF-TF PF00319.18 KIY72482.1 - 1.1e-22 79.3 0.0 1.6e-22 78.7 0.0 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) UAA PF08449.11 KIY72483.1 - 1.3e-45 155.9 14.4 5.1e-45 154.0 14.4 1.8 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 KIY72483.1 - 7.8e-12 45.5 15.7 1.8e-08 34.7 4.4 3.5 3 1 0 3 3 3 2 EamA-like transporter family Nuc_sug_transp PF04142.15 KIY72483.1 - 0.00042 19.6 3.6 0.1 11.7 0.4 2.3 2 0 0 2 2 2 2 Nucleotide-sugar transporter Cation_ATPase_C PF00689.21 KIY72483.1 - 0.18 11.5 7.2 1.8 8.2 7.2 2.8 1 1 0 1 1 1 0 Cation transporting ATPase, C-terminus DUF373 PF04123.13 KIY72483.1 - 2 7.8 5.9 2.1 7.7 3.9 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF373) Anoctamin PF04547.12 KIY72484.1 - 4.3e-93 312.6 11.5 5.5e-93 312.3 11.5 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Smim3 PF17307.2 KIY72484.1 - 0.59 9.7 2.9 25 4.5 2.4 2.5 2 0 0 2 2 2 0 Small integral membrane protein 3 cobW PF02492.19 KIY72486.1 - 1.4e-38 132.3 0.1 1.9e-38 131.8 0.1 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 KIY72486.1 - 4.1e-06 26.6 0.0 7.9e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain DSPc PF00782.20 KIY72487.1 - 1.3e-28 99.5 0.0 1.6e-28 99.2 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KIY72487.1 - 0.032 13.8 0.0 0.036 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 KIY72487.1 - 0.064 13.6 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Rit1 DUSP-like domain ADH_zinc_N PF00107.26 KIY72488.1 - 1.8e-09 37.6 1.5 4e-09 36.5 1.5 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIY72488.1 - 6.3e-09 35.7 0.0 1.4e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain GTP_EFTU PF00009.27 KIY72489.1 - 9.1e-58 195.0 0.0 1.5e-57 194.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 KIY72489.1 - 3.8e-16 58.9 0.0 8.8e-16 57.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 KIY72489.1 - 4.5e-10 39.5 0.1 1.9e-09 37.5 0.0 2.0 2 0 0 2 2 2 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 KIY72489.1 - 1.4e-05 25.3 0.0 4.1e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KIY72489.1 - 0.00024 21.2 0.0 0.0006 19.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.18 KIY72489.1 - 0.0025 17.1 0.0 0.0046 16.3 0.0 1.3 1 0 0 1 1 1 1 Septin EFG_IV PF03764.18 KIY72489.1 - 0.14 12.0 0.0 0.77 9.6 0.0 2.3 1 1 0 1 1 1 0 Elongation factor G, domain IV RasGEF PF00617.19 KIY72491.1 - 2.3e-54 184.3 0.2 4.3e-54 183.4 0.2 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KIY72491.1 - 4.3e-21 75.1 0.1 1.1e-20 73.8 0.1 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.28 KIY72491.1 - 4.9e-15 54.9 0.2 9.1e-15 54.0 0.2 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KIY72491.1 - 1.1e-12 47.6 0.1 2.4e-12 46.5 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KIY72491.1 - 1.6e-12 46.9 0.0 3.2e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.26 KIY72491.1 - 1.8e-06 27.9 0.0 0.038 14.1 0.0 2.7 2 0 0 2 2 2 2 WW domain Sec63 PF02889.16 KIY72493.1 - 7.6e-163 539.8 0.1 4.3e-90 301.3 0.0 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 KIY72493.1 - 3.8e-48 163.6 0.1 2.7e-25 89.1 0.1 3.2 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 KIY72493.1 - 3.4e-32 110.9 0.0 1.1e-31 109.3 0.0 2.0 1 0 0 1 1 1 1 N-terminal helicase PWI domain ResIII PF04851.15 KIY72493.1 - 8.1e-24 84.5 0.0 1.7e-13 50.9 0.0 2.7 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KIY72493.1 - 2.8e-13 50.2 0.0 4.4e-08 33.4 0.0 3.9 2 2 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 KIY72493.1 - 7.3e-06 26.3 1.3 0.24 11.7 0.1 3.6 3 1 0 3 3 3 2 AAA domain PhoH PF02562.16 KIY72493.1 - 0.0013 18.2 0.0 0.018 14.5 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein T2SSE PF00437.20 KIY72493.1 - 0.0027 16.8 0.0 0.038 13.0 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_7 PF12775.7 KIY72493.1 - 0.01 15.4 0.0 0.66 9.5 0.0 2.6 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF603 PF04645.12 KIY72493.1 - 0.067 12.9 0.1 0.15 11.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF603 NIF PF03031.18 KIY72494.1 - 2.5e-19 69.6 0.1 1.3e-18 67.3 0.0 1.9 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase WD40 PF00400.32 KIY72495.1 - 1.7e-08 35.0 0.5 0.037 14.9 0.0 3.8 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY72495.1 - 3e-05 24.2 0.0 0.00034 20.9 0.0 2.4 1 1 2 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIY72495.1 - 0.0054 15.7 0.0 0.018 14.0 0.0 1.8 2 0 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF2415 PF10313.9 KIY72495.1 - 0.1 12.5 0.1 10 6.2 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised protein domain (DUF2415) Crystall PF00030.19 KIY72496.1 - 0.0003 20.9 0.2 0.00045 20.4 0.2 1.3 1 0 0 1 1 1 1 Beta/Gamma crystallin ADH_zinc_N PF00107.26 KIY72497.1 - 8.1e-10 38.8 0.0 1.3e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIY72497.1 - 2.1e-08 34.0 0.0 7.1e-08 32.3 0.0 1.8 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KIY72497.1 - 3.5e-05 24.9 0.0 0.00013 23.0 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ORF6C PF10552.9 KIY72498.1 - 0.062 13.4 0.1 0.18 11.9 0.0 1.7 2 0 0 2 2 2 0 ORF6C domain GalP_UDP_tr_C PF02744.17 KIY72498.1 - 0.16 11.7 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, C-terminal domain GST_N PF02798.20 KIY72500.1 - 3.2e-17 62.6 0.0 5.7e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KIY72500.1 - 2.6e-16 59.8 0.0 4.4e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KIY72500.1 - 8.3e-15 54.8 0.2 1.5e-14 53.9 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KIY72500.1 - 1.7e-11 44.2 0.0 3e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KIY72500.1 - 2.6e-07 30.7 0.0 5.6e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KIY72500.1 - 7e-05 22.8 0.0 0.00015 21.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF3995 PF13160.6 KIY72501.1 - 0.39 11.1 6.7 0.87 10.0 2.4 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF3995) TctB PF07331.11 KIY72501.1 - 3.9 7.8 8.3 13 6.0 8.2 2.0 1 1 1 2 2 2 0 Tripartite tricarboxylate transporter TctB family Phage_holin_3_1 PF05106.12 KIY72501.1 - 4.6 7.8 5.4 3.6 8.1 0.4 2.4 2 0 0 2 2 2 0 Phage holin family (Lysis protein S) Mon1 PF03164.14 KIY72503.1 - 3.2e-119 398.6 0.0 4.1e-119 398.3 0.0 1.1 1 0 0 1 1 1 1 Trafficking protein Mon1 BTB PF00651.31 KIY72504.1 - 3e-07 30.6 0.0 7.2e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain adh_short PF00106.25 KIY72505.1 - 2.7e-06 27.0 0.0 7.9e-06 25.5 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KIY72505.1 - 0.0071 16.3 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 KR domain zf-C2H2_4 PF13894.6 KIY72507.1 - 8.2e-05 23.1 0.7 0.85 10.6 0.0 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KIY72507.1 - 0.0014 19.0 4.0 0.023 15.1 0.1 3.0 3 1 0 3 3 3 1 Zinc finger, C2H2 type Zn-C2H2_12 PF18112.1 KIY72507.1 - 0.04 14.4 1.0 0.43 11.1 0.7 2.6 2 1 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-H2C2_5 PF13909.6 KIY72507.1 - 0.076 12.8 3.6 1.8 8.4 0.5 3.0 2 1 0 2 2 2 0 C2H2-type zinc-finger domain FHA PF00498.26 KIY72508.1 - 1.1e-15 57.7 0.0 2.1e-15 56.8 0.0 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KIY72508.1 - 1.1e-05 25.6 0.0 0.0004 20.6 0.0 2.2 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain DUF3910 PF13049.6 KIY72508.1 - 0.062 13.6 0.1 0.18 12.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3910) Phage_holin_3_5 PF16085.5 KIY72509.1 - 0.081 13.1 0.4 0.081 13.1 0.4 1.8 2 0 0 2 2 2 0 Bacteriophage holin Hol, superfamily III DAO PF01266.24 KIY72510.1 - 0.0006 19.5 0.1 0.002 17.8 0.0 1.7 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIY72510.1 - 0.0023 17.2 0.1 0.0041 16.4 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KIY72510.1 - 0.0029 17.0 0.3 0.95 8.7 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 KIY72510.1 - 0.012 16.2 0.0 0.023 15.2 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KIY72510.1 - 0.068 12.0 0.1 12 4.6 0.0 2.8 3 0 0 3 3 3 0 Tryptophan halogenase FAM216B PF15107.6 KIY72511.1 - 0.14 12.0 0.2 0.28 11.1 0.2 1.4 1 0 0 1 1 1 0 FAM216B protein family Pkinase PF00069.25 KIY72512.1 - 2e-60 204.4 0.7 3.8e-60 203.5 0.0 1.9 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY72512.1 - 4.7e-34 117.8 0.0 8e-34 117.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.16 KIY72512.1 - 9.6e-22 76.9 18.4 4.7e-12 45.8 3.8 2.5 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.22 KIY72512.1 - 3.1e-20 71.8 27.7 4e-12 45.8 10.2 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 KIY72512.1 - 6.1e-10 39.7 0.4 2.7e-09 37.6 0.3 2.3 2 0 0 2 2 2 1 Protein kinase C terminal domain C2 PF00168.30 KIY72512.1 - 1.1e-07 32.0 0.0 2.2e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 C2 domain Kinase-like PF14531.6 KIY72512.1 - 0.0095 15.3 0.0 0.024 14.0 0.0 1.6 2 0 0 2 2 2 1 Kinase-like C1_2 PF03107.16 KIY72512.1 - 0.35 11.2 23.2 0.73 10.2 8.2 2.4 2 0 0 2 2 2 0 C1 domain Uds1 PF15456.6 KIY72512.1 - 4.5 7.4 13.3 4.6 7.4 1.1 2.9 2 1 0 2 2 2 0 Up-regulated During Septation DASH_Dad1 PF08649.10 KIY72514.1 - 6.6e-15 55.0 0.8 8.1e-15 54.8 0.8 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 Aldo_ket_red PF00248.21 KIY72516.1 - 7.8e-76 255.1 0.0 8.9e-76 254.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF3808 PF10300.9 KIY72518.1 - 6.4e-75 252.7 0.0 1.6e-74 251.4 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3808) TPR_14 PF13428.6 KIY72518.1 - 1.2e-05 25.7 2.1 9.1 7.4 0.0 4.8 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 KIY72518.1 - 8.5e-05 22.4 1.3 2.2 8.6 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 KIY72518.1 - 0.011 16.0 0.3 24 5.3 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 KIY72518.1 - 0.14 12.0 0.6 1.8 8.5 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 KIY72518.1 - 0.24 11.7 3.8 27 5.3 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 KIY72518.1 - 0.28 11.7 7.1 3.6 8.2 0.1 4.6 4 1 2 6 6 6 0 Tetratricopeptide repeat PT PF04886.12 KIY72519.1 - 6.4e-10 38.4 3.4 8.8e-05 22.0 3.4 2.7 1 1 0 1 1 1 1 PT repeat DUF3432 PF11914.8 KIY72519.1 - 0.014 15.6 16.5 0.29 11.4 16.5 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF3432) Bacteriocin_IIc PF10439.9 KIY72519.1 - 1.3 9.2 4.8 43 4.3 4.8 2.3 1 1 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide TCRP1 PF14944.6 KIY72519.1 - 1.4 8.8 9.2 1.1e+02 2.6 9.2 2.2 1 1 0 1 1 1 0 Tongue Cancer Chemotherapy Resistant Protein 1 Sld5 PF05916.11 KIY72521.1 - 0.00035 21.0 0.0 0.00045 20.6 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein SLD5_C PF16922.5 KIY72521.1 - 0.036 14.2 0.3 0.068 13.4 0.3 1.5 1 0 0 1 1 1 0 DNA replication complex GINS protein SLD5 C-terminus FmrO PF07091.11 KIY72521.1 - 0.037 13.6 0.0 0.049 13.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) PfkB PF00294.24 KIY72524.1 - 3.1e-52 177.8 0.8 3.9e-52 177.4 0.8 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase SQS_PSY PF00494.19 KIY72525.1 - 2.3e-56 191.2 0.0 2.8e-56 190.9 0.0 1.0 1 0 0 1 1 1 1 Squalene/phytoene synthase F-box-like PF12937.7 KIY72526.1 - 0.33 10.9 1.2 8 6.4 0.0 3.3 3 0 0 3 3 3 0 F-box-like NDUF_B12 PF08122.12 KIY72527.1 - 0.21 11.7 0.8 7.9 6.6 0.1 2.7 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family Tropomyosin_1 PF12718.7 KIY72528.1 - 1.2e-24 87.1 22.6 1.8e-20 73.6 12.8 2.1 1 1 1 2 2 2 2 Tropomyosin like Tropomyosin PF00261.20 KIY72528.1 - 3.3e-10 39.7 26.4 7e-10 38.7 26.4 1.5 1 1 0 1 1 1 1 Tropomyosin GAS PF13851.6 KIY72528.1 - 1.1e-05 24.9 21.0 1.3e-05 24.6 21.0 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding T3SSipB PF16535.5 KIY72528.1 - 0.00014 22.4 13.6 0.00017 22.1 13.6 1.2 1 0 0 1 1 1 1 Type III cell invasion protein SipB ERM PF00769.19 KIY72528.1 - 0.0027 17.5 30.9 0.0029 17.5 30.9 1.0 1 0 0 1 1 1 1 Ezrin/radixin/moesin family DUF1664 PF07889.12 KIY72528.1 - 0.0043 17.1 5.0 0.0043 17.1 5.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1664) DUF484 PF04340.12 KIY72528.1 - 0.0051 16.5 10.6 0.0064 16.2 10.6 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF484 CENP-F_leu_zip PF10473.9 KIY72528.1 - 0.0066 16.5 23.4 0.0066 16.5 23.4 1.3 1 1 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 EzrA PF06160.12 KIY72528.1 - 0.0075 14.5 15.0 0.01 14.0 15.0 1.3 1 1 0 1 1 1 1 Septation ring formation regulator, EzrA XhlA PF10779.9 KIY72528.1 - 0.012 15.8 2.2 0.012 15.8 2.2 3.2 1 1 2 3 3 3 0 Haemolysin XhlA TRAF_BIRC3_bd PF16673.5 KIY72528.1 - 0.013 15.3 3.7 0.013 15.3 3.7 2.5 2 1 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain BRE1 PF08647.11 KIY72528.1 - 0.013 15.5 21.4 0.029 14.4 8.5 2.2 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase Jnk-SapK_ap_N PF09744.9 KIY72528.1 - 0.014 15.6 24.9 0.017 15.4 24.9 1.1 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 ATG16 PF08614.11 KIY72528.1 - 0.016 15.5 22.8 0.024 14.9 22.8 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) SOGA PF11365.8 KIY72528.1 - 0.016 16.3 14.2 0.016 16.3 14.2 1.9 1 1 1 2 2 2 0 Protein SOGA Uso1_p115_C PF04871.13 KIY72528.1 - 0.018 15.4 14.5 0.018 15.4 14.5 2.0 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Sec34 PF04136.15 KIY72528.1 - 0.02 14.8 4.6 0.02 14.8 4.6 2.0 1 1 1 2 2 2 0 Sec34-like family KLRAQ PF10205.9 KIY72528.1 - 0.025 14.8 6.5 0.025 14.8 6.5 2.1 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein CLZ PF16526.5 KIY72528.1 - 0.041 14.2 21.3 1.2 9.6 5.7 2.5 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels MAD PF05557.13 KIY72528.1 - 0.054 11.9 19.6 0.062 11.7 19.6 1.0 1 0 0 1 1 1 0 Mitotic checkpoint protein APG6_N PF17675.1 KIY72528.1 - 0.071 13.6 32.7 0.092 13.3 17.9 2.0 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF4200 PF13863.6 KIY72528.1 - 0.12 12.8 24.0 0.18 12.2 12.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Prp19 PF08606.11 KIY72528.1 - 0.14 12.1 11.0 0.065 13.2 5.4 2.3 1 1 1 2 2 2 0 Prp19/Pso4-like PspA_IM30 PF04012.12 KIY72528.1 - 0.21 11.1 24.7 0.71 9.4 9.0 2.0 1 1 1 2 2 2 0 PspA/IM30 family Laminin_II PF06009.12 KIY72528.1 - 0.24 11.4 11.6 0.53 10.3 11.0 1.9 1 1 0 1 1 1 0 Laminin Domain II FliD_C PF07195.12 KIY72528.1 - 0.29 10.5 9.9 5.9 6.2 9.9 2.1 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus FPP PF05911.11 KIY72528.1 - 0.32 9.1 21.2 0.34 9.1 21.2 1.0 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil NPV_P10 PF05531.12 KIY72528.1 - 0.33 11.4 4.6 1.2 9.7 0.8 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein TPR_MLP1_2 PF07926.12 KIY72528.1 - 0.34 11.0 27.5 1.7 8.7 8.5 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein TMPIT PF07851.13 KIY72528.1 - 0.58 9.3 9.2 0.7 9.1 9.2 1.2 1 0 0 1 1 1 0 TMPIT-like protein Nsp1_C PF05064.13 KIY72528.1 - 0.61 9.9 15.5 0.33 10.8 5.4 2.8 1 1 2 3 3 3 0 Nsp1-like C-terminal region CorA PF01544.18 KIY72528.1 - 0.64 9.3 11.5 0.88 8.8 11.5 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Acyl-CoA_dh_2 PF08028.11 KIY72528.1 - 0.66 10.2 6.9 0.85 9.9 6.2 1.6 1 1 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain CREPT PF16566.5 KIY72528.1 - 0.67 10.1 14.7 0.064 13.4 8.7 1.9 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour BLOC1_2 PF10046.9 KIY72528.1 - 0.84 10.0 15.0 3.5 8.0 10.6 2.7 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4094 PF13334.6 KIY72528.1 - 0.89 10.0 9.9 0.074 13.5 3.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) Fzo_mitofusin PF04799.13 KIY72528.1 - 0.92 9.0 10.2 0.45 10.1 6.9 2.0 1 1 2 3 3 3 0 fzo-like conserved region DUF724 PF05266.14 KIY72528.1 - 1.1 9.0 18.8 0.084 12.7 8.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Spc7 PF08317.11 KIY72528.1 - 1.2 7.9 23.1 2.3 7.0 23.1 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF4472 PF14739.6 KIY72528.1 - 1.3 9.8 20.2 0.58 10.9 12.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) DUF4446 PF14584.6 KIY72528.1 - 1.6 8.7 10.9 0.27 11.2 2.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) V_ATPase_I PF01496.19 KIY72528.1 - 1.7 6.5 14.4 1.9 6.3 14.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Rootletin PF15035.6 KIY72528.1 - 1.7 8.6 21.6 0.16 12.0 13.4 2.1 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion ADIP PF11559.8 KIY72528.1 - 2 8.5 20.9 2.3 8.3 18.1 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Fib_alpha PF08702.10 KIY72528.1 - 2.6 8.2 9.9 2.1 8.5 7.6 1.8 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family TMCO5 PF14992.6 KIY72528.1 - 2.8 7.4 18.4 5 6.6 18.4 1.5 1 1 0 1 1 1 0 TMCO5 family DUF4407 PF14362.6 KIY72528.1 - 2.9 7.2 18.7 3.7 6.8 18.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FixO PF02433.15 KIY72528.1 - 3.1 7.2 7.8 0.63 9.5 3.9 1.6 1 1 1 2 2 2 0 Cytochrome C oxidase, mono-heme subunit/FixO DUF3584 PF12128.8 KIY72528.1 - 3.1 5.2 21.8 3.3 5.1 21.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF812 PF05667.11 KIY72528.1 - 3.6 6.3 18.8 5 5.9 18.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF2203 PF09969.9 KIY72528.1 - 3.8 8.2 17.0 0.92 10.2 7.6 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Exonuc_VII_L PF02601.15 KIY72528.1 - 4.3 6.8 14.8 4.6 6.7 14.8 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit rRNA_proc-arch PF13234.6 KIY72528.1 - 5.7 6.8 12.6 0.43 10.4 2.9 2.3 1 1 1 2 2 2 0 rRNA-processing arch domain Occludin_ELL PF07303.13 KIY72528.1 - 6.5 7.5 12.3 9.1 7.1 4.5 2.8 1 1 1 2 2 2 0 Occludin homology domain OmpH PF03938.14 KIY72528.1 - 7.9 6.8 22.5 3.1 8.1 17.3 2.3 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) FUSC PF04632.12 KIY72528.1 - 8 4.9 13.9 9.2 4.7 13.9 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family UPF0242 PF06785.11 KIY72528.1 - 8.6 6.4 23.1 66 3.5 23.1 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Cep57_CLD_2 PF14197.6 KIY72528.1 - 8.7 6.5 24.5 23 5.2 11.9 3.0 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 BST2 PF16716.5 KIY72528.1 - 8.8 7.0 20.5 1.5 9.5 9.6 2.5 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 KELK PF15796.5 KIY72528.1 - 9.4 6.8 24.7 3.3 8.2 4.4 3.0 1 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Nup54 PF13874.6 KIY72528.1 - 9.5 6.3 16.9 73 3.5 16.9 2.0 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 KIP1 PF07765.12 KIY72528.1 - 9.6 6.4 8.9 1.2 9.4 0.9 2.7 1 1 1 2 2 2 0 KIP1-like protein Glyco_hydro_71 PF03659.14 KIY72529.1 - 1.2e-124 415.9 8.1 1.5e-124 415.7 8.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Git3 PF11710.8 KIY72530.1 - 0.0022 17.8 5.5 0.011 15.6 5.5 2.0 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 DUF2723 PF11028.8 KIY72530.1 - 0.0096 15.9 3.3 3.8 7.4 0.1 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF2723) DUF3810 PF12725.7 KIY72530.1 - 1.2 8.4 4.1 1.2 8.5 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) HNH_2 PF13391.6 KIY72531.1 - 1.1e-09 38.2 0.0 1.9e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 HNH endonuclease Glyoxal_oxid_N PF07250.11 KIY72532.1 - 1.2e-30 106.5 0.3 1.6e-16 60.2 0.0 4.2 2 1 2 4 4 4 3 Glyoxal oxidase N-terminus DUF1929 PF09118.11 KIY72532.1 - 1e-21 77.0 0.0 2e-21 76.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Podoplanin PF05808.11 KIY72532.1 - 0.00063 19.9 2.4 0.0016 18.5 2.4 1.7 1 0 0 1 1 1 1 Podoplanin Kelch_4 PF13418.6 KIY72532.1 - 0.0022 18.0 5.5 0.55 10.3 0.2 4.7 4 0 0 4 4 4 1 Galactose oxidase, central domain Herpes_gE PF02480.16 KIY72532.1 - 0.012 14.4 0.0 0.019 13.7 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF456 PF04306.13 KIY72532.1 - 0.1 12.9 4.8 0.21 11.9 4.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF456) DUF647 PF04884.14 KIY72534.1 - 6.8e-73 245.2 2.5 9e-73 244.8 2.5 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis PROCT PF08084.11 KIY72534.1 - 0.14 12.0 0.0 0.86 9.5 0.0 2.1 2 0 0 2 2 2 0 PROCT (NUC072) domain SelB-wing_2 PF09106.11 KIY72534.1 - 0.15 12.3 0.0 0.32 11.2 0.0 1.6 1 0 0 1 1 1 0 Elongation factor SelB, winged helix DUF2139 PF09910.9 KIY72535.1 - 0.08 12.1 0.0 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2139) FokI_C PF02980.16 KIY72535.1 - 0.11 12.6 0.0 0.2 11.7 0.0 1.4 1 1 0 1 1 1 0 Restriction endonuclease FokI, catalytic domain zf-RING_2 PF13639.6 KIY72536.1 - 2.5e-11 43.7 7.8 4.1e-11 43.0 7.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KIY72536.1 - 9.7e-09 35.4 4.6 2.1e-08 34.3 4.6 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KIY72536.1 - 2.4e-07 30.5 8.3 4e-07 29.8 8.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KIY72536.1 - 1.3e-06 28.3 1.4 2.5e-06 27.4 0.3 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KIY72536.1 - 2e-06 27.6 4.1 3.2e-06 26.9 4.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KIY72536.1 - 1.6e-05 24.9 3.3 3e-05 24.0 3.3 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 KIY72536.1 - 1.7e-05 24.5 5.3 2.9e-05 23.8 5.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIY72536.1 - 5.3e-05 23.1 6.4 8.8e-05 22.4 6.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 KIY72536.1 - 0.00055 19.6 3.8 0.00055 19.6 3.8 2.4 3 0 0 3 3 3 1 RING-like zinc finger RINGv PF12906.7 KIY72536.1 - 0.04 14.0 4.2 0.069 13.3 4.2 1.3 1 0 0 1 1 1 0 RING-variant domain Prok-RING_4 PF14447.6 KIY72536.1 - 0.2 11.5 7.9 0.28 11.1 6.0 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 KIY72536.1 - 0.4 10.4 5.7 0.67 9.6 5.7 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 KIY72536.1 - 0.5 10.6 5.3 1.1 9.4 5.3 1.6 1 1 0 1 1 1 0 FANCL C-terminal domain zf-P11 PF03854.14 KIY72536.1 - 0.94 9.2 5.6 2.8 7.7 5.7 1.8 1 1 0 1 1 1 0 P-11 zinc finger Menin PF05053.13 KIY72536.1 - 3.9 5.7 5.8 0.34 9.2 0.1 1.9 2 0 0 2 2 2 0 Menin F-box-like PF12937.7 KIY72537.1 - 0.034 14.0 0.0 0.094 12.6 0.0 1.8 1 0 0 1 1 1 0 F-box-like F-box_4 PF15966.5 KIY72537.1 - 0.13 12.2 0.0 0.32 10.9 0.0 1.7 1 0 0 1 1 1 0 F-box bZIP_1 PF00170.21 KIY72538.1 - 0.061 13.4 9.7 0.11 12.7 9.7 1.4 1 0 0 1 1 1 0 bZIP transcription factor NBD94 PF16830.5 KIY72538.1 - 0.074 13.5 2.1 0.091 13.2 1.1 1.6 1 1 0 1 1 1 0 Nucleotide-Binding Domain 94 of RH bZIP_2 PF07716.15 KIY72538.1 - 0.34 11.0 11.3 0.94 9.6 10.0 2.4 2 1 1 3 3 3 0 Basic region leucine zipper NAM-associated PF14303.6 KIY72538.1 - 0.83 10.3 9.3 0.086 13.6 5.2 1.5 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain bZIP_Maf PF03131.17 KIY72538.1 - 2.2 8.8 10.0 4.8 7.8 9.8 1.7 1 1 0 1 1 1 0 bZIP Maf transcription factor ABC_tran_Xtn PF12848.7 KIY72538.1 - 4.9 7.2 11.4 8.5 6.5 11.4 1.3 1 0 0 1 1 1 0 ABC transporter DUF1840 PF08895.11 KIY72539.1 - 0.16 12.4 0.0 0.29 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) zf-C2H2 PF00096.26 KIY72540.1 - 2.1e-06 27.9 2.6 0.01 16.2 0.3 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_11 PF16622.5 KIY72540.1 - 1.8e-05 24.4 0.8 0.0036 17.0 0.2 2.4 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-C2H2_4 PF13894.6 KIY72540.1 - 0.00012 22.6 0.6 0.094 13.6 0.1 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 KIY72540.1 - 0.0014 18.8 0.3 0.21 11.7 0.2 2.1 2 0 0 2 2 2 1 Aberrant zinc-finger zf-H2C2_5 PF13909.6 KIY72540.1 - 0.002 17.9 2.6 0.032 14.0 0.3 2.5 2 0 0 2 2 2 1 C2H2-type zinc-finger domain FOXP-CC PF16159.5 KIY72540.1 - 0.0077 16.8 0.2 0.19 12.4 0.0 2.2 1 1 1 2 2 2 1 FOXP coiled-coil domain zf-C2H2_2 PF12756.7 KIY72540.1 - 0.024 15.0 0.5 0.053 13.8 0.4 1.5 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.12 KIY72540.1 - 0.028 14.7 0.2 0.23 11.8 0.2 2.1 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 KIY72540.1 - 0.11 12.8 0.2 1.9 8.9 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf_Hakai PF18408.1 KIY72540.1 - 0.39 10.5 0.1 0.39 10.5 0.1 2.6 2 1 0 2 2 2 0 C2H2 Hakai zinc finger domain zf-H2C2_2 PF13465.6 KIY72542.1 - 0.01 16.2 0.7 0.027 14.9 0.7 1.7 1 0 0 1 1 1 0 Zinc-finger double domain zf-C2H2 PF00096.26 KIY72542.1 - 0.074 13.5 3.6 3.3 8.3 0.4 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type APG12 PF04110.13 KIY72547.1 - 4.2e-29 100.8 0.0 5.3e-29 100.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.16 KIY72547.1 - 0.044 14.0 0.0 0.052 13.7 0.0 1.1 1 0 0 1 1 1 0 Autophagy protein Atg8 ubiquitin like Nramp PF01566.18 KIY72548.1 - 2.5e-86 289.9 19.5 2.2e-48 165.1 4.2 2.2 2 0 0 2 2 2 2 Natural resistance-associated macrophage protein adh_short_C2 PF13561.6 KIY72549.1 - 1.9e-52 178.1 6.0 2.7e-52 177.7 6.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIY72549.1 - 1.7e-42 145.1 4.1 2.3e-42 144.7 4.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIY72549.1 - 1.1e-07 32.0 0.4 1.7e-07 31.3 0.4 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KIY72549.1 - 0.0099 15.0 0.1 0.015 14.4 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein HGTP_anticodon PF03129.20 KIY72550.1 - 6.1e-23 80.8 0.0 1.3e-22 79.7 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 KIY72550.1 - 2.6e-10 40.5 0.0 1.3e-09 38.3 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Oxidored-like PF09791.9 KIY72552.1 - 0.11 12.2 0.8 0.18 11.5 0.8 1.3 1 0 0 1 1 1 0 Oxidoreductase-like protein, N-terminal TRAPP PF04051.16 KIY72554.1 - 7.1e-35 119.9 0.0 9.3e-35 119.5 0.0 1.2 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component dCMP_cyt_deam_1 PF00383.23 KIY72555.1 - 3.2e-09 36.6 0.4 5.9e-08 32.5 0.4 2.2 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region DUF2782 PF11191.8 KIY72555.1 - 0.044 14.0 0.0 0.073 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2782) 3-HAO PF06052.12 KIY72556.1 - 4e-53 179.1 0.1 4.6e-53 178.9 0.1 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.11 KIY72556.1 - 4e-06 26.4 0.2 6.4e-06 25.8 0.2 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 KIY72556.1 - 0.0014 18.3 0.1 0.0018 17.9 0.1 1.1 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.19 KIY72556.1 - 0.0031 17.4 0.1 0.0046 16.9 0.1 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Goodbye PF17109.5 KIY72558.1 - 1.6e-06 28.5 0.0 4.7e-06 27.1 0.0 1.8 2 0 0 2 2 2 1 fungal STAND N-terminal Goodbye domain T4SS-DNA_transf PF02534.14 KIY72558.1 - 0.013 14.4 0.2 0.018 13.8 0.2 1.1 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer Lar_restr_allev PF14354.6 KIY72558.1 - 0.16 12.3 0.4 0.31 11.4 0.4 1.4 1 0 0 1 1 1 0 Restriction alleviation protein Lar zf-C2HC_2 PF13913.6 KIY72558.1 - 0.4 10.6 2.8 0.19 11.7 0.3 1.8 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Goodbye PF17109.5 KIY72559.1 - 1.8e-05 25.2 0.0 6.8e-05 23.3 0.0 2.0 2 0 0 2 2 2 1 fungal STAND N-terminal Goodbye domain Herpes_BBRF1 PF04793.12 KIY72559.1 - 0.051 12.6 1.1 0.082 11.9 1.1 1.4 1 1 0 1 1 1 0 BRRF1-like protein Goodbye PF17109.5 KIY72560.1 - 2.7e-05 24.6 0.2 0.0001 22.7 0.0 2.0 2 0 0 2 2 2 1 fungal STAND N-terminal Goodbye domain DUF4145 PF13643.6 KIY72560.1 - 0.46 10.7 2.4 2.1 8.5 0.0 3.1 4 1 0 4 4 4 0 Domain of unknown function (DUF4145) Spt4 PF06093.13 KIY72561.1 - 2e-28 98.3 0.3 2.4e-28 98.0 0.3 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Lipase_3 PF01764.25 KIY72562.1 - 9.4e-16 58.0 0.0 1.9e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 KIY72562.1 - 0.1 11.9 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Hce2 PF14856.6 KIY72563.1 - 0.012 15.9 0.6 0.017 15.4 0.6 1.2 1 0 0 1 1 1 0 Pathogen effector; putative necrosis-inducing factor F-box-like PF12937.7 KIY72565.1 - 0.0069 16.3 0.0 0.016 15.1 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY72565.1 - 0.028 14.3 0.1 0.088 12.7 0.1 1.9 1 0 0 1 1 1 0 F-box domain Glyco_hydro_61 PF03443.14 KIY72566.1 - 2.3e-64 217.1 0.0 2.8e-64 216.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Metallophos PF00149.28 KIY72567.1 - 3.2e-36 125.7 0.0 5.1e-36 125.1 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase bZIP_1 PF00170.21 KIY72568.1 - 2.7e-06 27.4 7.9 4.4e-06 26.7 7.9 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KIY72568.1 - 1.1e-05 25.4 13.5 1.8e-05 24.7 13.5 1.3 1 0 0 1 1 1 1 Basic region leucine zipper DUF4200 PF13863.6 KIY72568.1 - 0.00084 19.7 6.1 0.0012 19.2 6.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4200) HIP1_clath_bdg PF16515.5 KIY72568.1 - 0.0012 19.4 2.1 0.0015 19.1 2.1 1.2 1 0 0 1 1 1 1 Clathrin-binding domain of Huntingtin-interacting protein 1 Selenoprotein_S PF06936.11 KIY72568.1 - 0.0025 17.6 2.2 0.0029 17.4 2.2 1.1 1 0 0 1 1 1 1 Selenoprotein S (SelS) bZIP_Maf PF03131.17 KIY72568.1 - 0.0027 18.2 3.1 0.0034 17.9 3.1 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor Takusan PF04822.13 KIY72568.1 - 0.0095 15.8 0.9 0.036 14.0 0.5 1.9 2 0 0 2 2 2 1 Takusan Atg14 PF10186.9 KIY72568.1 - 0.011 14.8 1.6 0.012 14.7 1.6 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 GAS PF13851.6 KIY72568.1 - 0.012 15.0 4.4 0.016 14.6 4.4 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Syntaxin-6_N PF09177.11 KIY72568.1 - 0.013 16.0 2.9 0.71 10.5 0.6 2.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal AAA_13 PF13166.6 KIY72568.1 - 0.014 14.0 0.4 0.016 13.9 0.4 1.0 1 0 0 1 1 1 0 AAA domain Dynamitin PF04912.14 KIY72568.1 - 0.025 13.9 2.6 0.027 13.8 2.6 1.0 1 0 0 1 1 1 0 Dynamitin FAM76 PF16046.5 KIY72568.1 - 0.052 12.9 0.9 0.061 12.7 0.9 1.0 1 0 0 1 1 1 0 FAM76 protein Phlebovirus_NSM PF07246.11 KIY72568.1 - 0.062 12.7 1.1 0.068 12.5 1.1 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M NAM-associated PF14303.6 KIY72568.1 - 0.069 13.9 2.7 0.082 13.6 2.7 1.1 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain DUF4140 PF13600.6 KIY72568.1 - 0.08 13.4 2.2 0.099 13.1 2.2 1.3 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) MCU PF04678.13 KIY72568.1 - 0.13 12.4 1.0 0.15 12.2 1.0 1.2 1 0 0 1 1 1 0 Mitochondrial calcium uniporter SVIP PF15811.5 KIY72568.1 - 0.15 12.5 7.0 0.3 11.5 7.0 1.5 1 0 0 1 1 1 0 Small VCP/p97-interacting protein Histone_HNS PF00816.21 KIY72568.1 - 1.1 10.1 6.3 2 9.3 0.5 2.1 1 1 1 2 2 2 0 H-NS histone family bZIP_2 PF07716.15 KIY72569.1 - 3.8e-05 23.7 16.1 0.00011 22.2 14.4 2.0 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 KIY72569.1 - 8.3e-05 22.6 13.4 0.00038 20.5 11.0 2.1 1 1 1 2 2 2 2 bZIP transcription factor bZIP_Maf PF03131.17 KIY72569.1 - 0.0026 18.2 8.4 0.0043 17.5 8.4 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor GAS PF13851.6 KIY72569.1 - 0.0042 16.4 5.2 0.0055 16.1 5.2 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding DUF3450 PF11932.8 KIY72569.1 - 0.0047 16.3 1.9 0.0062 15.9 1.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) DUF4200 PF13863.6 KIY72569.1 - 0.0094 16.3 3.5 0.014 15.8 3.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4200) CENP-F_leu_zip PF10473.9 KIY72569.1 - 0.017 15.1 3.3 0.023 14.8 3.3 1.1 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.11 KIY72569.1 - 0.02 15.1 4.5 0.03 14.6 4.5 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) APG6_N PF17675.1 KIY72569.1 - 0.066 13.7 6.1 0.096 13.2 6.1 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region Takusan PF04822.13 KIY72569.1 - 0.071 13.0 1.3 0.12 12.3 1.3 1.3 1 0 0 1 1 1 0 Takusan Ribosomal_L30_N PF08079.12 KIY72569.1 - 0.76 10.1 11.3 1.3 9.3 11.3 1.3 1 0 0 1 1 1 0 Ribosomal L30 N-terminal domain bZIP_Maf PF03131.17 KIY72570.1 - 3.9 8.0 10.7 0.76 10.3 6.6 2.0 2 0 0 2 2 2 0 bZIP Maf transcription factor Bestrophin PF01062.21 KIY72571.1 - 8.1e-33 114.1 0.8 1.7e-21 76.9 0.0 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel YjbT PF17089.5 KIY72571.1 - 0.013 15.4 0.3 0.079 13.0 0.1 2.1 2 0 0 2 2 2 0 Uncharacterised protein family ADH_zinc_N PF00107.26 KIY72572.1 - 2.2e-25 89.2 0.2 3.7e-25 88.4 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KIY72572.1 - 4.5e-16 60.1 0.1 6.7e-16 59.5 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIY72572.1 - 1.6e-09 37.6 0.1 6.6e-09 35.6 0.0 2.2 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain DUF4112 PF13430.6 KIY72573.1 - 9.2e-25 87.0 3.2 1.1e-24 86.7 3.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) Glyco_hydro_61 PF03443.14 KIY72574.1 - 3.3e-61 206.8 0.3 4e-61 206.6 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Goodbye PF17109.5 KIY72578.1 - 0.00078 19.9 0.0 0.0014 19.0 0.0 1.4 1 0 0 1 1 1 1 fungal STAND N-terminal Goodbye domain Lar_restr_allev PF14354.6 KIY72578.1 - 0.035 14.5 0.8 0.063 13.7 0.8 1.4 1 0 0 1 1 1 0 Restriction alleviation protein Lar Zn_Tnp_IS1595 PF12760.7 KIY72578.1 - 0.044 13.8 3.4 0.11 12.5 3.4 1.6 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zinc_ribbon_9 PF14369.6 KIY72578.1 - 0.055 13.7 0.7 13 6.1 0.1 2.6 2 0 0 2 2 2 0 zinc-ribbon OrfB_Zn_ribbon PF07282.11 KIY72578.1 - 0.11 12.5 2.4 0.13 12.2 0.8 1.8 2 0 0 2 2 2 0 Putative transposase DNA-binding domain zf-ribbon_3 PF13248.6 KIY72578.1 - 0.11 12.0 3.4 2.4 7.7 0.6 2.3 2 0 0 2 2 2 0 zinc-ribbon domain IBR PF01485.21 KIY72578.1 - 0.11 12.7 0.5 0.24 11.7 0.5 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain DZR PF12773.7 KIY72578.1 - 0.21 11.6 0.9 0.39 10.8 0.9 1.3 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_13 PF09855.9 KIY72578.1 - 0.47 10.7 1.7 1.5 9.0 0.9 2.3 1 1 1 2 2 2 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) zinc_ribbon_2 PF13240.6 KIY72578.1 - 0.51 10.1 2.5 0.59 9.9 0.2 2.0 2 0 0 2 2 2 0 zinc-ribbon domain TFIIS_C PF01096.18 KIY72578.1 - 1.5 8.8 3.7 9.7 6.1 3.7 2.1 1 1 0 1 1 1 0 Transcription factor S-II (TFIIS) zf-CHCC PF10276.9 KIY72578.1 - 1.9 8.6 4.4 0.27 11.3 0.4 1.7 2 0 0 2 2 2 0 Zinc-finger domain DUF983 PF06170.12 KIY72578.1 - 4 7.9 6.8 1.7 9.1 3.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF983) UPF0547 PF10571.9 KIY72578.1 - 5.5 7.2 10.9 3.2 7.9 0.2 3.1 4 0 0 4 4 3 0 Uncharacterised protein family UPF0547 Methyltransf_2 PF00891.18 KIY72579.1 - 4.1e-14 52.4 0.0 5.2e-11 42.2 0.0 2.3 2 0 0 2 2 2 2 O-methyltransferase domain HTH_IclR PF09339.10 KIY72579.1 - 0.025 14.4 0.5 0.053 13.3 0.5 1.6 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_5 PF01022.20 KIY72579.1 - 0.09 12.7 0.0 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family RNA_pol_Rpc34 PF05158.12 KIY72579.1 - 0.1 12.0 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase Rpc34 subunit MFS_1 PF07690.16 KIY72580.1 - 1.9e-34 119.2 41.8 1.9e-34 119.2 41.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIY72580.1 - 8.2e-06 24.9 33.9 0.00049 19.1 33.9 2.9 1 1 0 1 1 1 1 Sugar (and other) transporter Trp_oprn_chp PF09534.10 KIY72580.1 - 0.016 15.1 4.8 0.023 14.5 0.0 2.9 3 1 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Beta-lactamase PF00144.24 KIY72584.1 - 1.2e-32 113.5 0.2 2.2e-32 112.6 0.2 1.3 1 0 0 1 1 1 1 Beta-lactamase Zn_clus PF00172.18 KIY72586.1 - 5.6e-07 29.6 14.1 1e-06 28.8 14.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KIY72586.1 - 0.027 13.5 0.0 0.059 12.4 0.0 1.5 1 0 0 1 1 1 0 Fungal specific transcription factor domain Herpes_capsid PF06112.11 KIY72586.1 - 0.65 10.1 5.8 1.1 9.3 5.8 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Fasciclin PF02469.22 KIY72587.1 - 1.4e-31 109.4 0.5 1.8e-18 67.0 0.1 2.4 2 0 0 2 2 2 2 Fasciclin domain Rad17 PF03215.15 KIY72588.1 - 7.1e-29 101.0 0.0 1.5e-28 100.0 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 KIY72588.1 - 3.8e-05 24.2 0.0 9.3e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KIY72588.1 - 0.00012 22.3 0.0 0.00035 20.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 KIY72588.1 - 0.00013 22.2 0.0 0.00036 20.8 0.0 1.7 1 0 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 KIY72588.1 - 0.00016 22.1 0.0 0.00039 20.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KIY72588.1 - 0.0031 17.3 0.1 0.0067 16.2 0.1 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KIY72588.1 - 0.0063 16.3 0.0 0.022 14.5 0.0 1.9 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 KIY72588.1 - 0.079 12.5 0.1 0.55 9.7 0.0 2.3 3 0 0 3 3 3 0 P-loop containing dynein motor region T2SSE PF00437.20 KIY72588.1 - 0.086 11.9 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein dsrm PF00035.26 KIY72589.1 - 5.5e-06 27.0 0.0 6.5e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Double-stranded RNA binding motif Peroxidase_2 PF01328.17 KIY72590.1 - 2.5e-46 158.6 0.0 3.3e-46 158.2 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 Zn_clus PF00172.18 KIY72591.1 - 2.9e-07 30.5 8.8 5.6e-07 29.6 8.8 1.5 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fer2_BFD PF04324.15 KIY72591.1 - 0.081 13.3 3.4 0.28 11.6 0.2 2.2 1 1 1 2 2 2 0 BFD-like [2Fe-2S] binding domain MFS_1 PF07690.16 KIY72592.1 - 2.4e-39 135.3 44.2 3.8e-39 134.6 38.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIY72592.1 - 1.4e-12 47.2 4.1 1.4e-12 47.2 4.1 3.0 2 1 0 2 2 2 1 Sugar (and other) transporter Sad1_UNC PF07738.13 KIY72593.1 - 1.1e-26 93.3 0.2 1.7e-26 92.7 0.2 1.3 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal OrfB_IS605 PF01385.19 KIY72593.1 - 0.95 9.7 4.3 0.97 9.7 1.4 2.4 2 0 0 2 2 2 0 Probable transposase Nramp PF01566.18 KIY72594.1 - 6.5e-84 281.9 19.7 9.9e-47 159.6 4.4 2.1 2 0 0 2 2 2 2 Natural resistance-associated macrophage protein PsaL PF02605.15 KIY72594.1 - 0.049 13.3 0.0 0.15 11.7 0.0 1.9 1 0 0 1 1 1 0 Photosystem I reaction centre subunit XI Pkinase_Tyr PF07714.17 KIY72595.1 - 3.1e-49 167.6 0.0 4.6e-49 167.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIY72595.1 - 5.2e-35 121.1 0.0 2.3e-23 82.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain RIO1 PF01163.22 KIY72595.1 - 0.017 14.7 0.0 0.037 13.6 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 KIY72595.1 - 0.038 13.3 0.0 0.091 12.1 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HSP70 PF00012.20 KIY72596.1 - 9.6e-52 176.0 2.9 9.6e-38 129.7 0.1 2.7 3 0 0 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.13 KIY72596.1 - 5.2e-05 22.2 0.3 0.00037 19.4 0.3 2.0 1 1 0 1 1 1 1 MreB/Mbl protein PilM_2 PF11104.8 KIY72596.1 - 0.014 14.5 0.0 0.055 12.5 0.0 1.9 2 1 0 2 2 2 0 Type IV pilus assembly protein PilM; FAD_binding_3 PF01494.19 KIY72597.1 - 1.5e-11 44.2 0.0 3.2e-11 43.1 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 KIY72597.1 - 0.015 14.3 0.0 0.024 13.7 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Glyco_hydro_61 PF03443.14 KIY72598.1 - 4.9e-61 206.3 0.1 9.5e-61 205.3 0.0 1.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 Pol_alpha_B_N PF08418.10 KIY72598.1 - 6.1 6.7 6.7 9.6 6.1 6.7 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Acetyltransf_3 PF13302.7 KIY72599.1 - 1.2e-20 74.6 0.0 1.6e-20 74.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KIY72599.1 - 0.00071 19.3 0.0 0.038 13.7 0.1 2.7 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIY72599.1 - 0.00072 19.5 0.0 0.015 15.2 0.0 2.1 2 0 0 2 2 2 1 FR47-like protein NAP PF00956.18 KIY72600.1 - 4e-87 291.8 4.1 6.5e-87 291.1 4.1 1.3 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) HNH_2 PF13391.6 KIY72601.1 - 1.4e-07 31.6 0.1 2.4e-07 30.8 0.1 1.4 1 0 0 1 1 1 1 HNH endonuclease DAO PF01266.24 KIY72603.1 - 4.3e-40 138.4 0.1 5.4e-40 138.0 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KIY72603.1 - 7.9e-05 22.0 0.0 0.00022 20.6 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KIY72603.1 - 0.00071 18.9 0.1 1 8.5 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KIY72603.1 - 0.0014 18.0 0.0 0.0025 17.2 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KIY72603.1 - 0.0019 18.4 0.1 0.0044 17.2 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KIY72603.1 - 0.0045 17.0 0.1 2.2 8.2 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding MCRA PF06100.11 KIY72603.1 - 0.057 12.2 0.0 0.076 11.8 0.0 1.1 1 0 0 1 1 1 0 MCRA family Defensin_big PF14862.6 KIY72603.1 - 0.15 12.4 1.8 0.31 11.4 1.8 1.5 1 0 0 1 1 1 0 Big defensin Thi4 PF01946.17 KIY72603.1 - 0.16 11.2 0.0 0.38 10.0 0.0 1.5 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.14 KIY72603.1 - 0.17 10.6 0.2 0.42 9.3 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein AA_permease PF00324.21 KIY72604.1 - 1.7e-123 412.7 34.7 2e-123 412.6 34.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KIY72604.1 - 2.5e-32 112.3 38.6 3.4e-32 111.8 38.6 1.1 1 0 0 1 1 1 1 Amino acid permease NAD_binding_4 PF07993.12 KIY72605.1 - 1.5e-27 96.4 0.0 2.2e-27 95.9 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 KIY72605.1 - 1.7e-10 40.7 0.0 2.5e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KIY72605.1 - 0.0032 16.5 0.0 0.0069 15.4 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KIY72606.1 - 7.6e-25 87.5 0.0 1.2e-24 86.9 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 KIY72606.1 - 4.8e-10 39.3 0.0 6.7e-10 38.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KIY72606.1 - 0.15 11.2 0.0 0.81 8.8 0.0 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein F-box-like PF12937.7 KIY72607.1 - 8.2e-09 35.2 0.1 2.4e-08 33.7 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY72607.1 - 0.04 13.8 0.1 0.13 12.2 0.1 1.8 1 0 0 1 1 1 0 F-box domain GIT_CC PF16559.5 KIY72607.1 - 3.5 7.6 4.1 0.72 9.8 0.2 1.8 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Aldedh PF00171.22 KIY72609.1 - 4.4e-183 609.0 0.4 5e-183 608.8 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KIY72609.1 - 1.6e-05 24.2 0.0 2.7e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.11 KIY72609.1 - 0.082 12.3 0.0 12 5.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) DUF5063 PF16702.5 KIY72609.1 - 0.089 13.2 0.0 0.16 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5063) OPT PF03169.15 KIY72610.1 - 2.2e-134 449.4 39.1 2.5e-134 449.2 39.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Thioredoxin PF00085.20 KIY72611.1 - 1.9e-27 95.3 0.0 2.2e-27 95.0 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KIY72611.1 - 5.4e-10 39.7 0.0 1e-09 38.8 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KIY72611.1 - 3.9e-07 30.3 0.0 5.9e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 KIY72611.1 - 3.1e-06 27.1 0.0 3.5e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KIY72611.1 - 9.5e-06 25.4 0.0 0.00028 20.6 0.0 2.0 1 1 1 2 2 2 1 Redoxin Thioredoxin_9 PF14595.6 KIY72611.1 - 1.2e-05 25.1 0.0 1.3e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 KIY72611.1 - 2.3e-05 23.9 0.0 2.5e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 KIY72611.1 - 0.0025 18.0 0.0 0.0035 17.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Glutaredoxin PF00462.24 KIY72611.1 - 0.012 15.9 0.0 0.019 15.2 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin Thioredoxin PF00085.20 KIY72613.1 - 1.4e-26 92.5 0.0 1.7e-26 92.2 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KIY72613.1 - 2.9e-08 34.1 0.0 1.2e-07 32.1 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 KIY72613.1 - 1.5e-06 28.0 0.0 1.8e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KIY72613.1 - 1.6e-05 25.1 0.0 0.0042 17.4 0.0 2.2 1 1 1 2 2 2 2 Thioredoxin-like Redoxin PF08534.10 KIY72613.1 - 5.3e-05 23.0 0.0 0.0007 19.3 0.0 1.9 1 1 1 2 2 2 1 Redoxin AhpC-TSA PF00578.21 KIY72613.1 - 0.0002 21.3 0.0 0.00024 21.0 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family OST3_OST6 PF04756.13 KIY72613.1 - 0.0002 20.8 0.0 0.00023 20.6 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Glutaredoxin PF00462.24 KIY72613.1 - 0.0005 20.2 0.0 0.00085 19.5 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin HyaE PF07449.11 KIY72613.1 - 0.0051 16.8 0.0 0.0072 16.3 0.0 1.2 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE Thioredoxin_7 PF13899.6 KIY72613.1 - 0.009 16.2 0.0 0.012 15.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_5 PF13743.6 KIY72613.1 - 0.02 14.6 0.1 0.032 13.9 0.0 1.4 1 1 0 1 1 1 0 Thioredoxin Phosducin PF02114.16 KIY72613.1 - 0.042 12.8 0.0 0.051 12.5 0.0 1.1 1 0 0 1 1 1 0 Phosducin Mem_trans PF03547.18 KIY72614.1 - 5.2e-26 91.0 0.7 5.3e-25 87.6 0.7 1.9 1 1 0 1 1 1 1 Membrane transport protein GH131_N PF18271.1 KIY72617.1 - 2.1e-54 184.9 0.2 2.9e-54 184.4 0.2 1.2 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain PNP_UDP_1 PF01048.20 KIY72618.1 - 3.9e-36 124.5 0.1 4.8e-36 124.2 0.1 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily UCH PF00443.29 KIY72619.1 - 1.7e-42 145.7 0.0 5.2e-42 144.1 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP_var PF17807.1 KIY72619.1 - 3.9e-24 84.2 3.1 3.6e-23 81.1 0.3 2.6 2 0 0 2 2 2 1 Variant UBP zinc finger UBA PF00627.31 KIY72619.1 - 4e-23 80.9 1.2 3.4e-11 42.8 0.5 2.6 2 0 0 2 2 2 2 UBA/TS-N domain zf-UBP PF02148.19 KIY72619.1 - 6.9e-23 80.8 18.4 5.6e-20 71.4 0.9 3.5 4 1 0 4 4 4 2 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 KIY72619.1 - 7e-18 65.3 0.0 3.4e-16 59.8 0.0 3.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-C2HE PF16278.5 KIY72619.1 - 0.03 14.8 0.2 12 6.5 0.0 3.1 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger DUF4766 PF15973.5 KIY72620.1 - 4.8 7.8 0.0 4.8 7.8 0.0 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF4766) CRM1_C PF08767.11 KIY72622.1 - 3.3e-103 345.2 0.0 1e-101 340.3 0.0 2.4 2 0 0 2 2 2 1 CRM1 C terminal Xpo1 PF08389.12 KIY72622.1 - 6.7e-33 113.9 3.9 6.7e-33 113.9 3.9 3.2 3 1 0 3 3 3 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 KIY72622.1 - 2e-30 104.3 1.0 2e-30 104.3 1.0 2.8 2 0 0 2 2 2 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 KIY72622.1 - 4.9e-24 84.2 0.4 7.8e-23 80.3 0.2 2.9 2 0 0 2 2 2 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 KIY72622.1 - 1.6e-15 56.3 0.2 3.2e-15 55.3 0.2 1.6 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 KIY72622.1 - 1.9e-14 53.3 0.5 1.7e-13 50.3 0.1 2.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain DUF717 PF05338.12 KIY72622.1 - 0.022 14.9 0.0 0.1 12.7 0.0 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF717) tRNA-synt_1d PF00750.19 KIY72622.1 - 0.094 11.6 0.0 0.26 10.2 0.0 1.6 2 0 0 2 2 2 0 tRNA synthetases class I (R) VID27_N PF17748.1 KIY72622.1 - 0.21 11.4 1.1 0.36 10.7 0.0 1.9 2 0 0 2 2 2 0 VID27 N-terminal region Glyco_hydro_28 PF00295.17 KIY72623.1 - 1.7e-35 122.6 2.3 6.6e-25 87.9 0.1 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 28 Beta_helix PF13229.6 KIY72623.1 - 0.0043 16.9 13.7 0.038 13.8 5.6 3.1 1 1 3 4 4 4 2 Right handed beta helix region Peptidase_M36 PF02128.15 KIY72625.1 - 2.8e-137 457.8 5.7 4.3e-137 457.2 5.7 1.3 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) Peptidase_M4_C PF02868.15 KIY72625.1 - 2e-06 27.8 0.2 5.7e-06 26.3 0.2 1.7 1 0 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain FTP PF07504.13 KIY72625.1 - 0.026 14.3 0.1 0.06 13.2 0.1 1.6 1 0 0 1 1 1 0 Fungalysin/Thermolysin Propeptide Motif GMC_oxred_N PF00732.19 KIY72626.1 - 4e-60 203.7 0.0 5.2e-60 203.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KIY72626.1 - 7.5e-32 110.8 0.1 1.5e-31 109.9 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KIY72626.1 - 0.0031 17.7 0.0 0.028 14.7 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KIY72626.1 - 0.0031 16.6 0.0 0.0055 15.8 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 KIY72626.1 - 0.039 13.5 0.3 0.22 11.0 0.3 2.1 1 1 0 1 1 1 0 FAD dependent oxidoreductase YL1_C PF08265.11 KIY72626.1 - 0.069 12.9 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 YL1 nuclear protein C-terminal domain Mqo PF06039.15 KIY72626.1 - 0.091 11.3 0.0 0.15 10.5 0.0 1.3 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) Thi4 PF01946.17 KIY72626.1 - 0.11 11.8 0.0 0.75 9.0 0.0 2.1 2 0 0 2 2 2 0 Thi4 family Apt1 PF10351.9 KIY72627.1 - 0.081 11.8 0.6 0.091 11.6 0.6 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain GH131_N PF18271.1 KIY72628.1 - 2.4e-53 181.4 1.1 3.2e-53 181.0 1.1 1.1 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain Tautomerase PF01361.21 KIY72628.1 - 1.5 8.8 3.0 1.9 8.4 0.0 2.6 3 0 0 3 3 3 0 Tautomerase enzyme GST_N_3 PF13417.6 KIY72629.1 - 6.4e-10 39.3 0.0 1.2e-09 38.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KIY72629.1 - 3.5e-08 33.6 0.0 5.9e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KIY72629.1 - 0.0011 19.1 0.0 0.0019 18.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KIY72629.1 - 0.0022 18.0 0.2 0.0067 16.4 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KIY72629.1 - 0.028 14.6 0.0 0.058 13.6 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain F-box-like PF12937.7 KIY72630.1 - 2.6e-07 30.4 0.4 1.2e-06 28.3 0.2 2.3 2 1 0 2 2 2 1 F-box-like HNH_2 PF13391.6 KIY72631.1 - 0.00011 22.2 0.1 0.00022 21.3 0.1 1.5 1 0 0 1 1 1 1 HNH endonuclease Cyclin PF08613.11 KIY72632.1 - 3.9e-13 50.1 0.0 6.8e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 KIY72632.1 - 6.1e-07 29.2 0.0 9.2e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Pkinase PF00069.25 KIY72633.1 - 9.5e-25 87.4 0.0 1.8e-24 86.5 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY72633.1 - 6.3e-17 61.7 0.0 7.5e-17 61.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIY72633.1 - 5.8e-06 25.3 0.1 7e-06 25.1 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 KIY72633.1 - 0.0027 17.3 0.1 0.0036 16.9 0.1 1.2 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 KIY72633.1 - 0.012 14.9 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Haspin_kinase PF12330.8 KIY72633.1 - 0.047 12.6 0.0 0.063 12.2 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Trp_repressor PF01371.19 KIY72633.1 - 0.077 13.1 0.0 2.7 8.2 0.0 2.2 2 0 0 2 2 2 0 Trp repressor protein Seadorna_VP7 PF07387.11 KIY72633.1 - 0.081 12.0 0.1 0.11 11.6 0.1 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Flavi_DEAD PF07652.14 KIY72633.1 - 0.13 12.3 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain Pkinase PF00069.25 KIY72635.1 - 4e-33 114.9 0.0 4.8e-33 114.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY72635.1 - 7.1e-24 84.5 0.0 9.2e-24 84.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KIY72635.1 - 0.00075 18.5 0.0 0.00085 18.4 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KIY72635.1 - 0.00086 18.2 0.0 0.0011 17.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KIY72635.1 - 0.0017 18.4 0.0 0.031 14.2 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 KIY72635.1 - 0.005 16.5 0.0 0.0067 16.0 0.0 1.2 1 0 0 1 1 1 1 RIO1 family PIP49_C PF12260.8 KIY72635.1 - 0.099 12.3 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Choline_kinase PF01633.20 KIY72635.1 - 0.15 11.6 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase PCNA_C PF02747.15 KIY72636.1 - 0.014 15.5 0.0 0.028 14.6 0.0 1.4 1 0 0 1 1 1 0 Proliferating cell nuclear antigen, C-terminal domain Peptidase_C54 PF03416.19 KIY72637.1 - 9.1e-102 340.2 0.0 1.2e-101 339.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 Cu_bind_CorA PF18252.1 KIY72637.1 - 0.063 12.9 1.8 0.12 12.0 1.8 1.4 1 0 0 1 1 1 0 Copper(I)-binding protein CorA Lin-8 PF03353.15 KIY72637.1 - 8.4 5.9 6.9 21 4.6 6.9 1.6 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Nop14 PF04147.12 KIY72637.1 - 9.7 4.3 11.8 3.3 5.8 7.5 1.9 2 0 0 2 2 2 0 Nop14-like family UPF0300 PF08594.10 KIY72638.1 - 0.12 11.6 0.1 0.43 9.8 0.0 1.7 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0300) DUF1391 PF07151.12 KIY72638.1 - 0.13 12.2 1.1 0.22 11.4 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1391) Glyco_hydro_53 PF07745.13 KIY72640.1 - 9.9e-88 294.4 0.0 1.1e-87 294.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 Cellulase PF00150.18 KIY72640.1 - 4.5e-05 23.0 0.0 5.5e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) MHC_I_2 PF14586.6 KIY72640.1 - 0.01 15.7 0.1 0.015 15.1 0.1 1.2 1 0 0 1 1 1 0 Class I Histocompatibility antigen, NKG2D ligand, domains 1 and 2 Bacteriocin_IIc PF10439.9 KIY72640.1 - 0.079 13.1 1.9 0.21 11.8 1.9 1.7 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide TatD_DNase PF01026.21 KIY72640.1 - 0.095 12.1 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 TatD related DNase Glyco_hydro_53 PF07745.13 KIY72641.1 - 4.8e-87 292.1 0.0 5.5e-87 291.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 Cellulase PF00150.18 KIY72641.1 - 2.9e-05 23.6 0.0 4.3e-05 23.1 0.0 1.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) TatD_DNase PF01026.21 KIY72641.1 - 0.047 13.1 0.0 0.071 12.5 0.0 1.2 1 0 0 1 1 1 0 TatD related DNase Bacteriocin_IIc PF10439.9 KIY72641.1 - 0.072 13.2 0.0 0.2 11.8 0.0 1.7 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide PCMT PF01135.19 KIY72641.1 - 0.076 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PIG-L PF02585.17 KIY72642.1 - 4.5e-22 79.1 0.0 6.1e-22 78.7 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase DUF1770 PF08589.10 KIY72643.1 - 0.00017 22.5 0.3 0.00046 21.1 0.1 1.8 1 1 1 2 2 2 1 Fungal protein of unknown function (DUF1770) MT0933_antitox PF14013.6 KIY72644.1 - 0.18 12.1 5.6 0.54 10.6 5.6 1.8 1 1 0 1 1 1 0 MT0933-like antitoxin protein LRR_6 PF13516.6 KIY72645.1 - 4.6e-05 23.1 24.1 0.051 13.7 0.2 7.0 7 0 0 7 7 7 3 Leucine Rich repeat LRR_4 PF12799.7 KIY72645.1 - 0.3 11.6 11.6 6.6 7.3 0.7 4.7 3 2 2 5 5 5 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KIY72645.1 - 7.1 6.6 6.2 1 9.3 0.7 2.4 2 1 0 2 2 2 0 F-box-like Lipase_GDSL_2 PF13472.6 KIY72647.1 - 1.5e-14 54.8 2.6 2e-14 54.4 2.6 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KIY72647.1 - 2.4e-09 37.5 0.1 3e-09 37.1 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Sec2p PF06428.11 KIY72648.1 - 2.8e-13 49.6 11.4 2.8e-13 49.6 11.4 2.2 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p DUF555 PF04475.12 KIY72648.1 - 0.14 12.5 0.3 0.34 11.2 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF555) Herpes_UL6 PF01763.16 KIY72648.1 - 1.1 7.7 7.4 0.14 10.6 2.5 1.7 1 1 1 2 2 2 0 Herpesvirus UL6 like V-SNARE PF05008.15 KIY72648.1 - 6 7.3 12.3 1.9 8.9 5.0 2.5 1 1 1 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Bax1-I PF01027.20 KIY72649.1 - 4.1e-41 141.1 22.6 5.2e-41 140.8 22.6 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 BaxI_1 PF12811.7 KIY72649.1 - 0.018 14.6 13.0 0.04 13.5 13.0 1.5 1 1 0 1 1 1 0 Bax inhibitor 1 like Peptidase_M28 PF04389.17 KIY72650.1 - 3.4e-20 72.6 0.0 5e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KIY72650.1 - 6.4e-09 35.8 0.0 1.9e-08 34.2 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 DEP PF00610.21 KIY72650.1 - 0.028 14.5 0.0 0.063 13.3 0.0 1.6 1 0 0 1 1 1 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Peptidase_M28 PF04389.17 KIY72651.1 - 3e-22 79.3 0.0 4.3e-22 78.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KIY72651.1 - 3.9e-08 33.2 0.0 6.4e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 DEP PF00610.21 KIY72651.1 - 0.023 14.7 0.0 0.049 13.7 0.0 1.5 1 0 0 1 1 1 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Eno-Rase_FAD_bd PF07055.12 KIY72651.1 - 0.17 12.3 0.4 4.5 7.8 0.1 2.3 2 0 0 2 2 2 0 Enoyl reductase FAD binding domain SPATA9 PF15824.5 KIY72653.1 - 0.086 12.1 0.2 0.13 11.5 0.2 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated protein 9 FSA_C PF10479.9 KIY72654.1 - 1.7 6.7 6.9 2.3 6.3 6.9 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus F-box-like PF12937.7 KIY72655.1 - 0.071 13.0 1.2 0.19 11.7 1.2 1.8 1 0 0 1 1 1 0 F-box-like Hemerythrin PF01814.23 KIY72658.1 - 2.3e-06 28.3 0.0 3.7e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain DFP PF04127.15 KIY72659.1 - 1.5e-20 73.8 0.1 1.1e-11 44.9 0.0 2.2 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein Peptidase_M9_N PF08453.10 KIY72659.1 - 0.063 13.0 0.2 0.11 12.2 0.2 1.4 1 0 0 1 1 1 0 Peptidase family M9 N-terminal PAS_9 PF13426.7 KIY72659.1 - 0.18 12.1 0.0 0.42 10.9 0.0 1.5 1 0 0 1 1 1 0 PAS domain MSA-2c PF12238.8 KIY72659.1 - 0.34 10.9 3.9 0.56 10.2 3.9 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c zf-C2H2_4 PF13894.6 KIY72660.1 - 9.1 7.4 7.3 1.4 10.0 2.4 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger F-box-like PF12937.7 KIY72661.1 - 2.2e-05 24.2 0.2 5.9e-05 22.9 0.2 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY72661.1 - 0.29 11.1 1.2 1.3 9.0 1.2 2.1 1 1 0 1 1 1 0 F-box domain RRM_1 PF00076.22 KIY72662.1 - 1.6e-10 40.6 0.0 2.5e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mitoc_mL59 PF18126.1 KIY72663.1 - 8.7e-39 132.8 3.6 1.3e-38 132.2 3.6 1.5 1 1 0 1 1 1 1 Mitochondrial ribosomal protein mL59 DUF2967 PF11179.8 KIY72663.1 - 0.058 11.5 10.1 0.071 11.2 10.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) Prenyltrans PF00432.21 KIY72664.1 - 1.6e-22 78.9 14.0 3.1e-08 33.2 0.1 6.5 7 0 0 7 7 7 4 Prenyltransferase and squalene oxidase repeat Zn_clus PF00172.18 KIY72665.1 - 8.3e-08 32.2 6.8 1.2e-07 31.7 6.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KIY72665.1 - 1.4e-05 24.3 0.0 2.1e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain PMG PF05287.12 KIY72666.1 - 0.041 13.9 0.1 0.041 13.9 0.1 2.9 3 0 0 3 3 3 0 PMG protein DUF2967 PF11179.8 KIY72666.1 - 0.093 10.8 13.1 0.12 10.4 13.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) DUF3646 PF12362.8 KIY72668.1 - 0.14 12.4 0.0 0.29 11.5 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III gamma and tau subunits C terminal UvrD_C PF13361.6 KIY72669.1 - 3.5e-14 53.0 0.0 1.5e-06 27.9 0.0 3.4 2 1 1 3 3 3 2 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 KIY72669.1 - 1.9e-12 47.4 0.5 2.2e-10 40.6 0.0 2.5 1 1 1 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 KIY72669.1 - 1.8e-08 34.9 0.0 1.2e-06 28.9 0.0 2.9 2 1 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.6 KIY72669.1 - 1.7e-05 24.5 0.2 0.14 12.0 0.0 3.3 3 0 0 3 3 3 2 UvrD-like helicase C-terminal domain AAA_22 PF13401.6 KIY72669.1 - 0.0078 16.5 0.0 0.024 14.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KIY72669.1 - 0.043 14.2 0.0 0.28 11.5 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.6 KIY72669.1 - 0.051 13.3 0.0 0.25 11.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain TPR_1 PF00515.28 KIY72669.1 - 0.063 13.1 2.4 2 8.4 0.0 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF592 PF04574.13 KIY72669.1 - 0.064 13.0 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF592) DEAD PF00270.29 KIY72669.1 - 0.11 12.2 0.6 0.62 9.8 0.1 2.3 2 0 0 2 2 2 0 DEAD/DEAH box helicase TPR_14 PF13428.6 KIY72669.1 - 0.25 12.2 7.8 20 6.4 0.2 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 KIY72669.1 - 0.34 11.1 9.1 0.72 10.1 0.1 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Peptidase_A4 PF01828.17 KIY72670.1 - 1.4e-72 243.6 19.1 1.6e-72 243.3 19.1 1.1 1 0 0 1 1 1 1 Peptidase A4 family Lipase_3 PF01764.25 KIY72671.1 - 2e-18 66.6 0.0 3.2e-18 66.0 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KIY72671.1 - 0.0038 17.8 0.0 0.0052 17.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIY72671.1 - 0.016 14.5 0.0 0.025 13.8 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Esterase PF00756.20 KIY72671.1 - 0.083 12.5 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Abhydrolase_5 PF12695.7 KIY72671.1 - 0.097 12.4 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family UvrD_C PF13361.6 KIY72673.1 - 6e-06 25.9 0.0 0.00088 18.7 0.0 3.2 3 1 0 3 3 3 1 UvrD-like helicase C-terminal domain UvrD_C_2 PF13538.6 KIY72673.1 - 2e-05 24.3 0.0 0.032 14.1 0.0 3.4 3 0 0 3 3 3 2 UvrD-like helicase C-terminal domain AAA_22 PF13401.6 KIY72673.1 - 0.00021 21.5 0.0 0.0036 17.6 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KIY72673.1 - 0.0034 17.7 0.0 0.4 11.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 KIY72673.1 - 0.0099 15.9 0.0 0.025 14.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_12 PF13087.6 KIY72673.1 - 0.049 13.2 0.0 1.1 8.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain UvrD-helicase PF00580.21 KIY72673.1 - 0.1 12.1 0.3 8.6 5.8 0.1 3.3 3 1 0 3 3 3 0 UvrD/REP helicase N-terminal domain TPR_7 PF13176.6 KIY72673.1 - 0.12 12.5 1.7 10 6.4 0.1 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 KIY72673.1 - 1.6 9.1 5.9 22 5.5 0.9 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 KIY72673.1 - 5.5 7.8 7.3 24 5.8 2.3 4.4 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KIY72673.1 - 8.3 7.5 12.3 1.1 10.3 1.3 4.3 3 1 0 3 3 3 0 Tetratricopeptide repeat UvrD_C PF13361.6 KIY72674.1 - 1.2e-07 31.5 0.0 1.5e-05 24.6 0.0 2.6 1 1 1 2 2 2 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 KIY72674.1 - 1.4e-06 28.0 0.0 0.00023 20.8 0.0 2.4 2 0 0 2 2 2 2 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.6 KIY72674.1 - 6.3e-06 25.9 0.0 0.12 12.3 0.0 2.9 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 KIY72674.1 - 1.8e-05 25.1 0.1 0.00018 21.8 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KIY72674.1 - 0.0029 17.9 0.0 0.013 15.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain TPR_7 PF13176.6 KIY72674.1 - 0.0055 16.7 0.4 1.7 8.9 0.0 3.6 2 0 0 2 2 2 1 Tetratricopeptide repeat ResIII PF04851.15 KIY72674.1 - 0.018 15.1 0.0 0.048 13.7 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DEAD PF00270.29 KIY72674.1 - 0.039 13.7 0.0 0.098 12.4 0.0 1.6 1 0 0 1 1 1 0 DEAD/DEAH box helicase TPR_14 PF13428.6 KIY72674.1 - 0.24 12.3 5.4 6 8.0 0.1 5.1 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-MYND PF01753.18 KIY72675.1 - 1.9e-08 34.2 10.7 3.1e-08 33.6 10.7 1.4 1 0 0 1 1 1 1 MYND finger Spt20 PF12090.8 KIY72676.1 - 0.034 13.8 6.2 0.042 13.5 6.2 1.2 1 0 0 1 1 1 0 Spt20 family Med15 PF09606.10 KIY72677.1 - 0.12 11.0 14.7 0.13 10.9 14.7 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Rrn6 PF10214.9 KIY72677.1 - 1.3 7.4 15.1 1.4 7.3 15.1 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Suf PF05843.14 KIY72677.1 - 1.6 8.6 7.0 1.5 8.7 7.0 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Med3 PF11593.8 KIY72677.1 - 3 6.9 16.9 3.6 6.7 16.9 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal TFIIA PF03153.13 KIY72677.1 - 3.6 7.5 17.7 3.7 7.5 17.7 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Cofilin_ADF PF00241.20 KIY72678.1 - 1.1e-22 80.1 0.3 1.2e-22 79.9 0.3 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Flagellin_IN PF07196.13 KIY72678.1 - 0.14 12.4 0.5 0.36 11.1 0.5 1.7 1 1 0 1 1 1 0 Flagellin hook IN motif HlyIII PF03006.20 KIY72679.1 - 8.3e-56 189.2 23.5 1e-55 188.9 23.5 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF3493 PF11998.8 KIY72679.1 - 2 8.6 7.2 32 4.8 0.0 3.4 2 1 1 3 3 3 0 Low psii accumulation1 / Rep27 Cnd3 PF12719.7 KIY72680.1 - 3.8e-84 282.4 11.9 2.5e-82 276.4 10.9 2.9 3 0 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain HEAT PF02985.22 KIY72680.1 - 4.9e-06 26.3 1.1 7.7 7.1 0.1 6.0 6 0 0 6 6 6 2 HEAT repeat Cnd1 PF12717.7 KIY72680.1 - 0.0015 18.6 6.2 0.72 9.9 1.0 4.7 3 2 2 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KIY72680.1 - 0.012 16.0 8.0 0.066 13.6 0.6 3.8 3 1 1 4 4 4 0 HEAT repeats RTP1_C1 PF10363.9 KIY72680.1 - 0.017 15.3 2.0 0.052 13.7 0.2 2.9 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 TIP120 PF08623.10 KIY72680.1 - 0.022 14.5 0.1 11 5.8 0.0 3.8 3 0 0 3 3 3 0 TATA-binding protein interacting (TIP20) EF-hand_2 PF09068.11 KIY72680.1 - 4.8 7.4 7.0 0.56 10.4 0.3 2.9 4 0 0 4 4 4 0 EF hand Lipase_GDSL_2 PF13472.6 KIY72681.1 - 1.1e-15 58.4 2.4 1.5e-15 58.0 2.4 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KIY72681.1 - 3.3e-10 40.3 0.1 4e-10 40.0 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 KIY72681.1 - 0.026 14.7 0.0 0.039 14.1 0.0 1.4 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family NAC PF01849.18 KIY72682.1 - 2.4e-23 81.8 0.1 4.2e-23 81.1 0.1 1.4 1 0 0 1 1 1 1 NAC domain Acetyltransf_1 PF00583.25 KIY72683.1 - 7.3e-18 64.9 0.0 1.2e-17 64.2 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KIY72683.1 - 5e-09 36.4 0.0 1e-08 35.4 0.0 1.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KIY72683.1 - 5.5e-07 29.6 0.0 7.5e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 KIY72683.1 - 9.9e-05 22.5 0.0 0.00015 21.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIY72683.1 - 0.00012 21.9 0.0 0.00075 19.4 0.0 1.9 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_3 PF13302.7 KIY72683.1 - 0.014 16.1 0.0 0.02 15.5 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KIY72683.1 - 0.016 15.3 0.0 0.02 15.0 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Formyl_trans_N PF00551.19 KIY72685.1 - 8.2e-23 81.1 0.0 1.2e-22 80.5 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 KIY72685.1 - 1e-09 38.5 0.0 1.8e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain ABC2_membrane PF01061.24 KIY72686.1 - 4.4e-78 261.5 49.3 9.6e-42 142.8 19.2 3.1 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KIY72686.1 - 6.3e-38 130.4 0.0 5.7e-19 69.0 0.0 2.8 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.12 KIY72686.1 - 1.5e-33 114.5 2.3 2.8e-28 97.7 0.1 3.0 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.6 KIY72686.1 - 2.8e-13 50.3 1.3 6e-13 49.2 0.2 2.2 2 0 0 2 2 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 KIY72686.1 - 2.4e-09 37.8 0.6 1.3e-05 25.6 0.2 2.7 2 0 0 2 2 2 2 AAA ATPase domain ABC2_membrane_3 PF12698.7 KIY72686.1 - 4.6e-08 32.6 44.7 0.00093 18.4 22.5 3.2 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_22 PF13401.6 KIY72686.1 - 1.1e-06 29.0 0.1 0.024 14.9 0.1 3.3 3 1 0 3 3 2 2 AAA domain RsgA_GTPase PF03193.16 KIY72686.1 - 1.3e-06 28.4 0.0 7e-05 22.8 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 KIY72686.1 - 0.00012 21.7 0.3 0.13 12.0 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KIY72686.1 - 0.00022 21.3 0.1 1 9.5 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase dNK PF01712.19 KIY72686.1 - 0.00044 20.2 0.0 0.018 14.9 0.0 2.3 2 0 0 2 2 2 1 Deoxynucleoside kinase NACHT PF05729.12 KIY72686.1 - 0.002 18.1 0.8 0.15 11.9 0.4 2.6 2 0 0 2 2 2 1 NACHT domain AAA_30 PF13604.6 KIY72686.1 - 0.0028 17.4 0.1 0.21 11.3 0.2 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KIY72686.1 - 0.0095 15.5 0.4 0.29 10.7 0.1 2.7 2 0 0 2 2 2 1 AAA domain DUF3600 PF12207.8 KIY72686.1 - 0.011 15.7 0.0 5.1 7.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3600) AAA_21 PF13304.6 KIY72686.1 - 0.012 15.5 0.3 4.1 7.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 KIY72686.1 - 0.013 16.1 0.0 1.6 9.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KIY72686.1 - 0.013 15.7 3.1 2.8 8.1 0.1 3.1 4 0 0 4 4 2 0 AAA domain cobW PF02492.19 KIY72686.1 - 0.016 14.8 1.7 0.94 9.0 0.4 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 KIY72686.1 - 0.023 14.9 0.4 2.4 8.4 0.4 2.8 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 KIY72686.1 - 0.052 13.5 0.0 4.2 7.2 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain Ploopntkinase3 PF18751.1 KIY72686.1 - 0.091 12.7 0.2 3.2 7.6 0.0 2.7 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 Rad51 PF08423.11 KIY72686.1 - 0.12 11.6 0.1 0.23 10.7 0.1 1.3 1 0 0 1 1 1 0 Rad51 PduV-EutP PF10662.9 KIY72686.1 - 0.13 12.0 1.0 4.4 7.0 0.1 2.7 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_17 PF13207.6 KIY72686.1 - 0.14 12.6 0.1 6.9 7.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KIY72686.1 - 0.17 11.8 0.9 3 7.7 0.3 3.1 4 0 0 4 4 4 0 NTPase Septin PF00735.18 KIY72686.1 - 0.2 10.9 0.0 10 5.3 0.1 2.3 2 0 0 2 2 2 0 Septin DUF389 PF04087.14 KIY72686.1 - 1.6 8.7 12.0 0.37 10.8 1.9 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF389) DUF1640 PF07798.11 KIY72687.1 - 0.021 14.9 0.6 0.031 14.3 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) DUF1192 PF06698.11 KIY72687.1 - 0.021 14.9 1.1 1 9.4 0.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1192) DivIC PF04977.15 KIY72687.1 - 0.023 14.4 2.5 0.29 10.9 0.3 2.3 1 1 1 2 2 2 0 Septum formation initiator FAM76 PF16046.5 KIY72687.1 - 0.03 13.7 0.1 0.032 13.6 0.1 1.1 1 0 0 1 1 1 0 FAM76 protein Phage_GP20 PF06810.11 KIY72687.1 - 0.048 13.5 0.2 0.071 12.9 0.2 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 Mto2_bdg PF12808.7 KIY72687.1 - 0.056 13.7 7.3 0.16 12.3 1.1 2.6 2 1 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region FlaC_arch PF05377.11 KIY72687.1 - 0.07 13.5 0.1 0.92 9.9 0.0 2.3 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) APG6_N PF17675.1 KIY72687.1 - 0.082 13.4 4.3 0.11 13.0 4.3 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region ZapB PF06005.12 KIY72687.1 - 0.085 13.3 3.1 2 8.9 3.1 2.5 1 1 0 1 1 1 0 Cell division protein ZapB TMF_DNA_bd PF12329.8 KIY72687.1 - 0.11 12.5 3.1 6.4 6.9 0.2 2.2 1 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF5595 PF18077.1 KIY72687.1 - 0.14 12.2 0.7 0.29 11.2 0.4 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF5595) YabA PF06156.13 KIY72687.1 - 0.32 11.7 1.4 5.1 7.8 0.4 2.2 1 1 1 2 2 2 0 Initiation control protein YabA Glyco_hydro_53 PF07745.13 KIY72688.1 - 2.5e-78 263.4 0.1 5.1e-77 259.1 0.1 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 53 Cellulase PF00150.18 KIY72688.1 - 0.00096 18.7 0.1 0.02 14.3 0.1 2.1 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF3274 PF11678.8 KIY72689.1 - 0.047 12.9 0.0 0.047 12.9 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3274) Rad52_Rad22 PF04098.15 KIY72690.1 - 5.7e-52 175.7 0.0 7.3e-52 175.3 0.0 1.0 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein DUF3326 PF11805.8 KIY72690.1 - 0.074 11.9 0.0 0.091 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3326) Mad3_BUB1_I PF08311.12 KIY72691.1 - 5.5e-34 116.8 0.1 8.4e-34 116.2 0.1 1.3 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Mad3_BUB1_I_2 PF17014.5 KIY72691.1 - 0.096 12.8 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 Putative Mad3/BUB1 like region 1 protein DUF2673 PF10880.8 KIY72692.1 - 0.011 15.8 2.0 0.016 15.3 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2673) Asp5 PF17000.5 KIY72693.1 - 0.00011 22.2 0.1 0.00024 21.2 0.1 1.5 1 0 0 1 1 1 1 Accessory secretory protein Sec, Asp5 RRM_1 PF00076.22 KIY72694.1 - 5e-38 128.8 0.0 4.5e-18 64.8 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 KIY72694.1 - 0.0024 17.9 0.1 1.1 9.4 0.1 2.9 3 0 0 3 3 3 2 Limkain b1 PABP PF00658.18 KIY72694.1 - 0.0072 16.5 0.4 0.45 10.7 0.1 2.7 3 0 0 3 3 3 1 Poly-adenylate binding protein, unique domain Nup35_RRM PF05172.13 KIY72694.1 - 0.043 13.8 0.0 0.092 12.7 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Pkinase PF00069.25 KIY72695.1 - 6.3e-23 81.5 0.1 2.4e-07 30.4 0.0 4.0 4 0 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.17 KIY72695.1 - 2.2e-12 46.8 0.0 0.00067 19.0 0.0 4.1 4 0 0 4 4 4 4 Protein tyrosine kinase SIS PF01380.22 KIY72696.1 - 2.3e-63 211.9 0.2 2.1e-32 111.7 0.1 2.5 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 KIY72696.1 - 1.3e-16 61.0 0.0 2.7e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KIY72696.1 - 3.3e-11 43.2 0.0 8.5e-11 41.8 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 KIY72696.1 - 0.00034 19.6 0.0 0.00059 18.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II GATase_2 PF00310.21 KIY72696.1 - 0.14 10.9 0.0 0.23 10.1 0.0 1.3 1 0 0 1 1 1 0 Glutamine amidotransferases class-II B12D PF06522.11 KIY72697.1 - 6.3e-08 32.3 0.0 8e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit OppC_N PF12911.7 KIY72697.1 - 0.033 14.2 0.1 0.044 13.8 0.1 1.2 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C adh_short PF00106.25 KIY72698.1 - 2.6e-19 69.5 0.0 2.2e-13 50.1 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KIY72698.1 - 4.6e-14 52.5 0.0 4.9e-09 36.1 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIY72698.1 - 3e-05 24.0 0.0 4.3e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 KR domain p450 PF00067.22 KIY72699.1 - 5.4e-74 249.6 0.0 9.8e-74 248.8 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.25 KIY72702.1 - 5.8e-63 212.7 0.0 1.1e-62 211.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY72702.1 - 1.1e-32 113.3 0.0 1.9e-32 112.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KIY72702.1 - 0.002 18.1 0.0 0.0086 16.0 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family HpcH_HpaI PF03328.14 KIY72703.1 - 3.2e-26 91.8 0.0 4.4e-26 91.4 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PK PF00224.21 KIY72703.1 - 0.00022 20.3 0.0 0.0004 19.4 0.0 1.4 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain MMR_HSR1 PF01926.23 KIY72704.1 - 1.2e-10 41.5 0.0 3.9e-10 39.8 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KIY72704.1 - 0.017 14.6 0.1 0.031 13.8 0.1 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B TniB PF05621.11 KIY72704.1 - 0.048 13.1 0.0 0.086 12.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA_16 PF13191.6 KIY72704.1 - 0.048 14.0 0.0 0.81 10.0 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain Arf PF00025.21 KIY72704.1 - 0.11 12.0 0.0 0.39 10.2 0.0 1.8 2 0 0 2 2 2 0 ADP-ribosylation factor family MCM PF00493.23 KIY72704.1 - 0.11 11.6 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 MCM P-loop domain RsgA_GTPase PF03193.16 KIY72704.1 - 0.12 12.3 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase Transp_cyt_pur PF02133.15 KIY72705.1 - 1.4e-112 376.7 32.6 1.7e-112 376.4 32.6 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Sec23_trunk PF04811.15 KIY72708.1 - 7e-73 245.2 0.0 1.1e-72 244.5 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 KIY72708.1 - 3.5e-29 101.4 0.1 8.4e-29 100.2 0.1 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 KIY72708.1 - 7.6e-26 89.9 0.1 1.9e-25 88.6 0.1 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 KIY72708.1 - 2.9e-16 59.2 6.1 5.1e-16 58.4 6.1 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KIY72708.1 - 1.1e-11 44.5 0.0 3.2e-11 43.0 0.0 1.9 2 0 0 2 2 2 1 Gelsolin repeat Vps36-NZF-N PF16988.5 KIY72708.1 - 0.03 13.7 0.1 0.058 12.8 0.1 1.4 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain PRIMA1 PF16101.5 KIY72709.1 - 3.6 7.7 11.7 0.42 10.7 6.8 1.9 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 DUF772 PF05598.11 KIY72715.1 - 0.054 13.5 0.7 0.78 9.8 0.1 2.5 2 0 0 2 2 2 0 Transposase domain (DUF772) AAA_34 PF13872.6 KIY72715.1 - 0.13 11.1 0.0 0.28 10.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 Trp_halogenase PF04820.14 KIY72719.1 - 5.2e-05 22.3 0.3 0.23 10.3 0.1 2.6 2 1 1 3 3 3 2 Tryptophan halogenase FAD_oxidored PF12831.7 KIY72719.1 - 0.0024 17.3 0.1 0.65 9.3 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIY72719.1 - 0.0033 16.7 0.0 0.011 15.0 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIY72719.1 - 0.013 15.2 0.1 0.15 11.6 0.1 2.1 1 1 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 KIY72719.1 - 0.061 13.9 0.0 0.12 13.0 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KIY72719.1 - 0.081 12.0 0.0 3.9 6.4 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain FAD_binding_3 PF01494.19 KIY72719.1 - 0.083 12.1 0.1 7.6 5.7 0.0 2.7 3 0 0 3 3 3 0 FAD binding domain Glyco_transf_90 PF05686.12 KIY72721.1 - 1.7e-13 50.3 2.1 3.2e-10 39.5 1.0 3.5 3 1 0 3 3 3 2 Glycosyl transferase family 90 Glyco_hydro_43 PF04616.14 KIY72723.1 - 1.9e-08 34.0 8.1 4.6e-08 32.7 3.5 2.9 1 1 1 2 2 2 1 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.20 KIY72723.1 - 0.00072 19.2 0.4 0.0023 17.5 0.0 2.0 3 1 0 3 3 3 1 Glycosyl hydrolases family 32 N-terminal domain Ribosom_S30AE_C PF16321.5 KIY72723.1 - 0.093 12.4 0.1 2 8.1 0.0 2.4 2 0 0 2 2 2 0 Sigma 54 modulation/S30EA ribosomal protein C terminus Med21 PF11221.8 KIY72724.1 - 4.5e-26 91.8 9.1 5.8e-26 91.5 9.1 1.1 1 0 0 1 1 1 1 Subunit 21 of Mediator complex Kinesin_assoc PF16183.5 KIY72724.1 - 0.021 15.0 1.1 0.027 14.6 1.1 1.1 1 0 0 1 1 1 0 Kinesin-associated Enkurin PF13864.6 KIY72724.1 - 0.16 12.4 4.4 0.13 12.8 1.9 1.9 1 1 0 2 2 2 0 Calmodulin-binding GrpE PF01025.19 KIY72724.1 - 0.22 11.2 4.2 0.41 10.3 4.2 1.8 1 1 0 1 1 1 0 GrpE Med30 PF11315.8 KIY72724.1 - 0.53 10.5 6.4 0.12 12.6 1.1 2.1 1 1 1 2 2 2 0 Mediator complex subunit 30 Cep57_MT_bd PF06657.13 KIY72724.1 - 0.91 10.0 12.6 2.5 8.6 2.0 3.1 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 PhoU PF01895.19 KIY72724.1 - 2 9.0 5.0 29 5.2 2.7 2.9 2 1 0 2 2 2 0 PhoU domain DUF2730 PF10805.8 KIY72724.1 - 2.4 8.3 6.3 0.74 9.9 1.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) p450 PF00067.22 KIY72726.1 - 5.2e-58 196.9 0.0 7.1e-58 196.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KIY72727.1 - 8.5e-62 209.4 0.0 1.1e-61 209.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.7 KIY72728.1 - 3.5e-08 33.2 4.8 1.5e-07 31.2 4.8 2.1 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KIY72728.1 - 0.046 13.6 0.2 0.046 13.6 0.2 2.2 2 0 0 2 2 2 0 F-box domain p450 PF00067.22 KIY72729.1 - 1.1e-59 202.4 0.0 1.5e-59 202.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KIY72730.1 - 2.2e-62 211.3 0.0 2.8e-62 211.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1749 PF08538.10 KIY72731.1 - 0.0014 17.8 0.1 0.0021 17.2 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.7 KIY72731.1 - 0.08 13.5 3.5 0.061 13.9 0.4 2.3 1 1 1 2 2 2 0 Alpha/beta hydrolase family F-box-like PF12937.7 KIY72732.1 - 0.00011 22.0 0.2 0.00021 21.1 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY72732.1 - 0.0026 17.6 0.4 0.0066 16.3 0.4 1.6 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KIY72732.1 - 0.12 12.3 0.1 0.6 10.0 0.0 2.3 2 0 0 2 2 2 0 F-box Pkinase PF00069.25 KIY72733.1 - 1.4e-74 250.8 0.0 2.7e-74 249.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY72733.1 - 2.3e-42 145.1 0.0 4e-42 144.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 KIY72733.1 - 3.8e-32 110.3 1.4 4.6e-17 62.0 0.1 2.5 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.6 KIY72733.1 - 3.8e-06 26.4 0.0 0.0014 18.0 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Haspin_kinase PF12330.8 KIY72733.1 - 0.0035 16.3 0.1 0.008 15.2 0.1 1.6 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KIY72733.1 - 0.011 15.1 0.1 0.034 13.5 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4520 PF15016.6 KIY72733.1 - 0.14 12.3 0.2 0.4 10.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4520) ADH_N PF08240.12 KIY72734.1 - 9.3e-28 96.3 2.6 9.3e-28 96.3 2.6 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KIY72734.1 - 1.5e-15 57.3 0.1 3.2e-15 56.3 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KIY72734.1 - 9.8e-08 33.1 0.0 1.9e-07 32.2 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KIY72734.1 - 0.00088 18.7 0.2 0.0015 18.0 0.2 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KIY72734.1 - 0.002 17.5 0.0 0.003 16.9 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Complex1_LYR PF05347.15 KIY72736.1 - 1.6e-07 31.2 0.0 1.9e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) MerR_2 PF13591.6 KIY72736.1 - 0.042 13.7 0.2 0.077 12.9 0.0 1.5 2 0 0 2 2 2 0 MerR HTH family regulatory protein LSM PF01423.22 KIY72737.1 - 9e-18 63.7 0.2 1.2e-17 63.3 0.2 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 KIY72737.1 - 0.0087 15.7 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 Hfq protein Pescadillo_N PF06732.11 KIY72738.1 - 1.7e-120 401.7 0.0 1.7e-120 401.7 0.0 2.0 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT_2 PF16589.5 KIY72738.1 - 8.2e-08 32.6 0.0 2.1e-07 31.3 0.0 1.7 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KIY72738.1 - 0.0035 17.7 0.0 0.008 16.5 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 KIY72738.1 - 0.014 15.7 0.0 0.037 14.3 0.0 1.8 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain Sec7 PF01369.20 KIY72739.1 - 3.5e-31 108.3 0.0 5.3e-31 107.7 0.0 1.2 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 KIY72739.1 - 2.9e-10 40.6 0.0 7e-10 39.3 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KIY72739.1 - 4.2e-07 30.4 0.1 1.3e-06 28.8 0.0 2.0 2 0 0 2 2 2 1 PH domain Lipase_chap PF03280.14 KIY72740.1 - 0.091 12.7 2.7 0.18 11.8 2.7 1.4 1 0 0 1 1 1 0 Proteobacterial lipase chaperone protein RNA_pol_Rpb8 PF03870.15 KIY72742.1 - 6.4e-46 156.0 0.0 7.2e-46 155.8 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 Big_8 PF17961.1 KIY72742.1 - 0.094 12.9 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial Ig domain TTL PF03133.15 KIY72743.1 - 2.3e-43 148.4 0.0 3.1e-43 148.0 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family MMM1 PF10296.9 KIY72744.1 - 8.9e-39 133.4 0.0 2.1e-28 99.4 0.0 3.0 1 1 0 2 2 2 2 Maintenance of mitochondrial morphology protein 1 HA2 PF04408.23 KIY72745.1 - 3.3e-16 59.5 0.1 1.1e-15 57.8 0.1 2.0 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KIY72745.1 - 1.6e-13 51.0 0.0 3.7e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 KIY72745.1 - 2.9e-11 43.6 0.0 6.3e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 KIY72745.1 - 3.7e-05 23.6 0.0 6.9e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KIY72745.1 - 0.0011 19.2 0.0 0.004 17.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 KIY72745.1 - 0.0016 18.9 0.1 0.039 14.5 0.0 2.8 3 0 0 3 3 3 1 ABC transporter T2SSE PF00437.20 KIY72745.1 - 0.053 12.6 0.0 0.13 11.3 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein PAM2 PF07145.15 KIY72745.1 - 0.06 13.1 0.2 0.15 11.8 0.2 1.7 1 0 0 1 1 1 0 Ataxin-2 C-terminal region MEIOC PF15189.6 KIY72745.1 - 0.12 11.9 1.9 1.2 8.7 0.0 3.1 3 0 0 3 3 3 0 Meiosis-specific coiled-coil domain-containing protein MEIOC DUF1685 PF07939.11 KIY72745.1 - 0.17 11.7 0.1 0.52 10.1 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1685) Pro_dh PF01619.18 KIY72746.1 - 1.5e-54 185.5 0.0 5e-54 183.8 0.0 1.7 1 1 0 1 1 1 1 Proline dehydrogenase GFO_IDH_MocA PF01408.22 KIY72747.1 - 1.1e-10 42.4 0.0 2.2e-10 41.4 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KIY72747.1 - 0.013 15.5 0.0 0.037 14.0 0.0 1.9 1 1 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain Sacchrp_dh_NADP PF03435.18 KIY72747.1 - 0.14 12.4 0.0 0.29 11.4 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Ras PF00071.22 KIY72749.1 - 7e-54 181.8 0.0 8.7e-54 181.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIY72749.1 - 1.2e-33 115.9 0.0 1.7e-33 115.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIY72749.1 - 1.6e-14 53.8 0.0 6.9e-14 51.7 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KIY72749.1 - 7.2e-06 25.5 0.0 8.4e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KIY72749.1 - 5.8e-05 22.7 0.0 7.1e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KIY72749.1 - 0.00034 20.7 0.0 0.00059 19.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KIY72749.1 - 0.00055 20.4 0.5 0.001 19.5 0.5 1.5 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 KIY72749.1 - 0.089 12.7 0.1 10 6.0 0.0 2.9 3 0 0 3 3 3 0 RsgA GTPase Arrestin_C PF02752.22 KIY72750.1 - 0.041 14.3 3.5 0.034 14.6 1.6 1.8 2 1 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain Sin_N PF04801.13 KIY72755.1 - 3.1e-23 82.7 0.0 4e-23 82.3 0.0 1.0 1 0 0 1 1 1 1 Sin-like protein conserved region DUF2771 PF10969.8 KIY72755.1 - 0.022 14.8 0.1 0.05 13.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2771) DUF1684 PF07920.11 KIY72755.1 - 0.032 14.5 0.1 0.075 13.3 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1684) Pkinase PF00069.25 KIY72757.1 - 1.1e-67 228.2 0.0 1.3e-67 227.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY72757.1 - 3.2e-28 98.7 0.0 4.4e-28 98.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY72757.1 - 3.4e-06 26.6 0.2 0.0017 17.7 0.1 2.2 1 1 1 2 2 2 2 Kinase-like RIO1 PF01163.22 KIY72757.1 - 0.0023 17.5 0.1 0.0037 16.9 0.1 1.2 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 KIY72757.1 - 0.1 11.5 0.1 0.31 10.0 0.1 1.7 1 1 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 KIY72757.1 - 0.18 11.7 0.1 0.28 11.1 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DKCLD PF08068.12 KIY72758.1 - 1.4e-32 111.5 0.1 7.3e-32 109.2 0.1 2.1 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_C_2 PF16198.5 KIY72758.1 - 2.2e-22 78.9 1.0 4.7e-22 77.9 1.0 1.6 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.20 KIY72758.1 - 3.2e-22 78.3 0.9 6.6e-22 77.3 0.9 1.6 1 0 0 1 1 1 1 PUA domain TruB_N PF01509.18 KIY72758.1 - 9.8e-22 77.9 3.7 7.4e-16 58.9 0.1 3.8 2 2 2 4 4 4 2 TruB family pseudouridylate synthase (N terminal domain) UPF0113 PF03657.13 KIY72758.1 - 0.0022 18.2 0.0 0.0057 16.9 0.0 1.7 1 0 0 1 1 1 1 UPF0113 PUA domain SOBP PF15279.6 KIY72758.1 - 1.8 9.1 5.0 2.8 8.4 5.0 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein BRF1 PF07741.13 KIY72760.1 - 0.25 11.7 6.9 0.14 12.5 4.6 1.7 2 0 0 2 2 2 0 Brf1-like TBP-binding domain TMEM40 PF15817.5 KIY72761.1 - 0.1 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein 40 family Septin PF00735.18 KIY72762.1 - 2.6e-110 368.1 0.0 4.3e-110 367.4 0.0 1.3 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KIY72762.1 - 4.9e-07 29.8 0.0 1.4e-06 28.3 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KIY72762.1 - 1.7e-05 24.4 0.3 0.0033 17.0 0.1 2.6 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain AIG1 PF04548.16 KIY72762.1 - 0.00038 19.8 0.0 0.00078 18.8 0.0 1.5 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 KIY72762.1 - 0.00091 19.3 2.5 0.39 10.7 0.0 3.0 2 1 1 3 3 3 2 Dynamin family RsgA_GTPase PF03193.16 KIY72762.1 - 0.0078 16.1 4.1 0.031 14.2 0.5 3.0 3 1 0 3 3 3 1 RsgA GTPase FtsK_SpoIIIE PF01580.18 KIY72762.1 - 0.035 13.5 0.1 0.089 12.1 0.1 1.7 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_22 PF13401.6 KIY72762.1 - 0.071 13.4 1.0 0.2 11.9 0.0 2.3 2 2 0 2 2 2 0 AAA domain Roc PF08477.13 KIY72762.1 - 0.077 13.2 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 KIY72762.1 - 0.13 12.7 2.5 2.6 8.5 2.3 2.2 2 0 0 2 2 2 0 AAA domain Gasdermin_C PF17708.1 KIY72762.1 - 0.36 10.9 4.0 0.3 11.2 2.4 1.7 2 0 0 2 2 2 0 Gasdermin PUB domain MutS_V PF00488.21 KIY72763.1 - 1.5e-65 220.8 0.0 3.6e-65 219.5 0.0 1.7 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 KIY72763.1 - 3.7e-41 141.5 0.3 9.4e-41 140.1 0.3 1.7 1 1 0 1 1 1 1 MutS domain III MutS_I PF01624.20 KIY72763.1 - 3.2e-22 78.9 0.0 7.7e-22 77.7 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 KIY72763.1 - 1.1e-09 38.7 0.1 5.9e-09 36.3 0.0 2.2 2 0 0 2 2 2 1 MutS domain II AAA_27 PF13514.6 KIY72763.1 - 0.00017 21.3 0.0 0.00034 20.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 KIY72763.1 - 0.0033 18.0 2.2 0.021 15.4 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KIY72763.1 - 0.0077 15.9 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain Chrome_Resist PF09828.9 KIY72763.1 - 0.052 14.0 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 Chromate resistance exported protein AAA_28 PF13521.6 KIY72763.1 - 0.075 13.3 0.0 0.6 10.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 KIY72763.1 - 0.093 12.8 0.0 0.29 11.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain CLZ PF16526.5 KIY72763.1 - 0.56 10.6 5.8 0.62 10.5 0.9 2.9 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ABC_tran PF00005.27 KIY72764.1 - 3.6e-41 140.9 0.0 1.8e-25 90.0 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KIY72764.1 - 2.8e-40 138.7 34.6 1.9e-21 76.9 8.5 2.7 3 0 0 3 3 2 2 ABC transporter transmembrane region SMC_N PF02463.19 KIY72764.1 - 6e-11 42.2 3.6 0.006 16.0 0.0 4.3 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KIY72764.1 - 4.8e-10 40.3 0.1 5.7e-07 30.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 KIY72764.1 - 3.7e-06 26.7 0.0 0.012 15.2 0.0 2.7 3 0 0 3 3 2 2 AAA domain AAA_21 PF13304.6 KIY72764.1 - 9.8e-06 25.6 2.9 0.011 15.5 0.0 4.0 3 1 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system T2SSE PF00437.20 KIY72764.1 - 1e-05 24.7 0.0 0.034 13.2 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_29 PF13555.6 KIY72764.1 - 1.3e-05 24.9 1.3 0.04 13.7 0.3 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KIY72764.1 - 1.7e-05 25.3 0.1 0.15 12.4 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 KIY72764.1 - 8.6e-05 22.6 0.7 0.097 12.8 0.0 3.0 3 0 0 3 3 2 1 50S ribosome-binding GTPase DUF87 PF01935.17 KIY72764.1 - 0.00041 20.5 0.1 0.3 11.2 0.1 2.6 2 0 0 2 2 2 1 Helicase HerA, central domain RsgA_GTPase PF03193.16 KIY72764.1 - 0.0019 18.1 0.5 1.7 8.5 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase IstB_IS21 PF01695.17 KIY72764.1 - 0.0031 17.3 0.0 4.4 7.0 0.0 3.2 3 0 0 3 3 2 1 IstB-like ATP binding protein NB-ARC PF00931.22 KIY72764.1 - 0.0071 15.6 0.0 0.71 9.0 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain FtsK_SpoIIIE PF01580.18 KIY72764.1 - 0.0083 15.5 0.7 1.1 8.6 0.2 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_7 PF12775.7 KIY72764.1 - 0.012 15.2 0.4 3.8 7.0 0.1 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_22 PF13401.6 KIY72764.1 - 0.016 15.5 2.1 0.92 9.8 0.1 3.0 2 1 0 2 2 2 0 AAA domain AAA_15 PF13175.6 KIY72764.1 - 0.016 14.9 0.1 0.24 11.0 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Adeno_IVa2 PF02456.15 KIY72764.1 - 0.017 13.9 0.1 2.5 6.8 0.0 2.3 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_5 PF07728.14 KIY72764.1 - 0.019 14.9 2.2 8.5 6.4 0.1 4.0 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KIY72764.1 - 0.024 15.2 0.0 15 6.2 0.0 3.6 4 0 0 4 4 3 0 AAA domain DEAD PF00270.29 KIY72764.1 - 0.037 13.8 0.0 13 5.5 0.0 2.6 2 0 0 2 2 2 0 DEAD/DEAH box helicase Dynamin_N PF00350.23 KIY72764.1 - 0.044 13.9 0.5 2.9 7.9 0.0 2.6 2 0 0 2 2 2 0 Dynamin family AAA_30 PF13604.6 KIY72764.1 - 0.055 13.2 0.5 1.4 8.6 0.0 3.0 2 1 0 2 2 2 0 AAA domain Roc PF08477.13 KIY72764.1 - 0.079 13.2 0.9 11 6.3 0.0 3.2 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase TrwB_AAD_bind PF10412.9 KIY72764.1 - 0.081 11.8 0.3 8.2 5.2 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain PduV-EutP PF10662.9 KIY72764.1 - 0.16 11.7 0.2 13 5.6 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATPase_2 PF01637.18 KIY72764.1 - 0.17 11.8 0.0 2.4 8.0 0.0 2.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea cobW PF02492.19 KIY72764.1 - 0.23 11.1 3.3 0.67 9.5 0.2 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Pox_A32 PF04665.12 KIY72764.1 - 0.29 10.6 1.3 13 5.2 0.2 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein Aa_trans PF01490.18 KIY72765.1 - 3.3e-53 180.9 18.9 4e-53 180.6 18.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KIY72765.1 - 0.0011 18.2 15.4 0.0027 16.8 15.4 2.0 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family CSN8_PSD8_EIF3K PF10075.9 KIY72766.1 - 1.4e-19 70.5 0.0 2.1e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family WD40 PF00400.32 KIY72767.1 - 3.6e-61 201.7 14.5 9.4e-11 42.1 0.5 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY72767.1 - 1.8e-26 92.3 0.3 1.5e-06 28.4 0.0 6.0 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KIY72767.1 - 4.8e-14 52.7 0.0 2e-06 27.9 0.0 3.8 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KIY72767.1 - 3.8e-11 42.3 5.1 0.0014 17.3 0.1 5.6 1 1 4 5 5 5 4 Nucleoporin Nup120/160 WD40_like PF17005.5 KIY72767.1 - 3.6e-08 33.1 0.0 3.1e-05 23.4 0.0 3.0 3 0 0 3 3 3 1 WD40-like domain Ge1_WD40 PF16529.5 KIY72767.1 - 4.1e-08 32.6 2.3 0.077 11.9 0.1 4.2 1 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PALB2_WD40 PF16756.5 KIY72767.1 - 0.0004 19.4 0.1 0.38 9.6 0.0 2.9 1 1 0 2 2 2 2 Partner and localizer of BRCA2 WD40 domain Coatomer_WDAD PF04053.14 KIY72767.1 - 0.0012 17.9 0.0 0.027 13.5 0.0 2.5 1 1 1 2 2 2 1 Coatomer WD associated region Nbas_N PF15492.6 KIY72767.1 - 0.002 17.5 0.1 1.6 8.0 0.0 3.1 1 1 2 3 3 3 2 Neuroblastoma-amplified sequence, N terminal DUF1513 PF07433.11 KIY72767.1 - 0.013 14.6 0.2 0.79 8.7 0.0 2.7 2 1 2 4 4 4 0 Protein of unknown function (DUF1513) Cytochrom_D1 PF02239.16 KIY72767.1 - 0.046 12.3 0.0 0.84 8.1 0.0 2.5 2 1 0 3 3 3 0 Cytochrome D1 heme domain IKI3 PF04762.12 KIY72767.1 - 0.053 11.5 0.3 1.7 6.5 0.0 2.6 2 1 1 3 3 3 0 IKI3 family Hira PF07569.11 KIY72767.1 - 0.09 12.5 0.6 23 4.6 0.0 3.5 3 1 1 4 4 4 0 TUP1-like enhancer of split BBS1 PF14779.6 KIY72767.1 - 0.11 11.9 0.0 0.32 10.4 0.0 1.7 2 1 0 2 2 2 0 Ciliary BBSome complex subunit 1 Frtz PF11768.8 KIY72767.1 - 0.13 10.6 0.0 4.3 5.5 0.0 2.1 1 1 1 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz VID27 PF08553.10 KIY72767.1 - 0.17 10.9 0.2 3 6.8 0.0 2.5 3 1 1 4 4 4 0 VID27 C-terminal WD40-like domain GST_N_3 PF13417.6 KIY72768.1 - 7e-11 42.4 0.0 1.2e-10 41.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KIY72768.1 - 3.1e-07 30.6 0.0 5.5e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KIY72768.1 - 0.00073 19.8 0.0 0.0013 19.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain CD34_antigen PF06365.12 KIY72769.1 - 0.078 12.6 0.2 0.13 11.8 0.1 1.4 1 1 0 1 1 1 0 CD34/Podocalyxin family Epimerase PF01370.21 KIY72770.1 - 5.9e-12 45.6 0.0 7.7e-12 45.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KIY72770.1 - 3.3e-10 39.9 0.0 5e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KIY72770.1 - 8.8e-08 31.5 0.0 1.2e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KIY72770.1 - 5.9e-05 22.4 0.0 0.0049 16.1 0.0 2.4 2 1 0 2 2 2 1 Male sterility protein RmlD_sub_bind PF04321.17 KIY72770.1 - 0.00016 20.9 0.0 0.00024 20.3 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 KIY72770.1 - 0.096 12.1 0.0 0.26 10.7 0.0 1.7 1 1 0 1 1 1 0 short chain dehydrogenase LacAB_rpiB PF02502.18 KIY72771.1 - 1.7e-45 154.4 0.9 2e-45 154.2 0.9 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase DUF4514 PF14986.6 KIY72771.1 - 0.082 12.9 0.6 0.34 10.9 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4514) KptA_kDCL PF18176.1 KIY72771.1 - 0.094 12.6 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 KptA in kinetoplastid DICER domain Dak1 PF02733.17 KIY72772.1 - 4.8e-97 324.6 0.8 1.2e-96 323.3 0.4 1.8 2 0 0 2 2 2 1 Dak1 domain Dak2 PF02734.17 KIY72772.1 - 1.8e-42 145.2 0.3 1.8e-42 145.2 0.3 1.8 2 0 0 2 2 2 1 DAK2 domain Fungal_trans PF04082.18 KIY72773.1 - 7.5e-26 90.7 0.2 1.5e-25 89.7 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY72773.1 - 1.5e-06 28.2 13.0 2.3e-06 27.6 13.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KIY72773.1 - 0.013 14.3 0.6 0.019 13.8 0.6 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain MFS_1 PF07690.16 KIY72774.1 - 4.8e-30 104.7 27.3 6.2e-30 104.3 27.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MNSV_P7B PF06692.11 KIY72774.1 - 1.1 9.3 4.7 0.39 10.7 0.4 2.5 3 0 0 3 3 3 0 Melon necrotic spot virus P7B protein DUF5392 PF17370.2 KIY72774.1 - 3.1 7.9 4.0 4.3 7.4 0.7 2.5 2 1 1 3 3 3 0 Family of unknown function (DUF5392) F_bP_aldolase PF01116.20 KIY72775.1 - 1.6e-67 227.9 0.0 1.8e-67 227.8 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Big_9 PF17963.1 KIY72776.1 - 0.065 14.0 10.9 0.064 14.0 2.2 2.6 2 1 0 2 2 2 0 Bacterial Ig domain Cadherin_4 PF17803.1 KIY72776.1 - 2 9.1 10.8 1.4 9.6 5.2 3.0 2 1 1 3 3 3 0 Bacterial cadherin-like domain BRCT_2 PF16589.5 KIY72777.1 - 2e-11 44.2 0.0 3.4e-07 30.6 0.0 2.3 1 1 1 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain Myb_DNA-bind_2 PF08914.11 KIY72777.1 - 2.5e-09 37.2 1.2 8.5e-09 35.5 1.2 1.9 1 1 0 1 1 1 1 Rap1 Myb domain DUF3949 PF13133.6 KIY72777.1 - 0.061 13.8 0.0 0.13 12.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3949) Rap1-DNA-bind PF09197.10 KIY72777.1 - 0.23 12.1 2.7 1.1 9.8 2.0 2.3 1 1 1 2 2 2 0 Rap1, DNA-binding GYF PF02213.16 KIY72778.1 - 2.8e-16 58.9 0.0 7.8e-16 57.5 0.0 1.8 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 KIY72778.1 - 0.0011 18.7 0.3 0.0048 16.7 0.0 2.1 2 0 0 2 2 2 1 GYF domain 2 FAD-oxidase_C PF02913.19 KIY72779.1 - 8.8e-55 186.0 0.0 1.1e-54 185.7 0.0 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KIY72779.1 - 9e-33 113.0 0.7 1.5e-32 112.3 0.7 1.3 1 0 0 1 1 1 1 FAD binding domain DUF1749 PF08538.10 KIY72779.1 - 0.039 13.0 0.0 0.068 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) AMP-binding PF00501.28 KIY72780.1 - 8.3e-78 261.8 0.1 9.8e-78 261.6 0.1 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KIY72780.1 - 4.1e-18 66.1 0.0 8.4e-18 65.1 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Alginate_lyase PF05426.12 KIY72781.1 - 5.4e-53 180.3 0.0 1.4e-50 172.4 0.0 2.1 2 0 0 2 2 2 2 Alginate lyase FMN_dh PF01070.18 KIY72782.1 - 1.5e-108 363.0 0.0 1.8e-108 362.7 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KIY72782.1 - 3.1e-22 78.5 0.0 7.3e-22 77.3 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NMO PF03060.15 KIY72782.1 - 6e-06 25.9 0.0 9.5e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase Glu_synthase PF01645.17 KIY72782.1 - 0.00039 19.7 0.3 0.0025 17.0 0.3 2.0 1 1 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KIY72782.1 - 0.00055 19.0 0.3 0.0043 16.1 0.1 2.2 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain His_Phos_1 PF00300.22 KIY72783.1 - 1.2e-22 80.6 0.0 4.6e-22 78.7 0.0 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Memo PF01875.17 KIY72784.1 - 8.7e-70 234.9 0.0 1e-69 234.7 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein Ribosomal_L32e PF01655.18 KIY72785.1 - 1.3e-50 170.3 2.0 1.5e-50 170.1 2.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 Pkinase PF00069.25 KIY72786.1 - 7.3e-39 133.7 0.0 1e-36 126.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIY72786.1 - 4.3e-17 62.3 0.0 1.3e-14 54.1 0.0 3.1 2 2 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KIY72786.1 - 0.0012 18.8 0.0 0.0022 17.9 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KIY72786.1 - 0.0026 17.1 0.0 0.005 16.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KIY72786.1 - 0.012 15.0 0.0 0.019 14.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KIY72786.1 - 0.021 13.6 0.0 0.033 13.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 KIY72786.1 - 0.099 12.2 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 RIO1 family GTP_EFTU PF00009.27 KIY72787.1 - 7.1e-53 179.0 0.1 1.1e-52 178.4 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KIY72787.1 - 1.2e-42 144.7 0.0 3.1e-42 143.4 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KIY72787.1 - 7.1e-12 45.6 1.0 7.1e-12 45.6 1.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KIY72787.1 - 0.0031 17.6 0.1 0.067 13.3 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Semialdhyde_dhC PF02774.18 KIY72787.1 - 0.055 13.5 0.1 0.48 10.5 0.0 2.1 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain NIF3 PF01784.18 KIY72787.1 - 0.12 12.0 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 NIF3 (NGG1p interacting factor 3) COesterase PF00135.28 KIY72788.1 - 3e-87 293.6 0.0 1.4e-85 288.2 0.0 2.0 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KIY72788.1 - 0.0015 18.4 0.5 0.0078 16.1 0.5 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KIY72788.1 - 0.42 10.1 2.1 0.77 9.2 1.1 1.7 1 1 1 2 2 2 0 Prolyl oligopeptidase family Velvet PF11754.8 KIY72789.1 - 3.7e-53 181.0 0.8 3.1e-35 122.3 0.1 3.3 3 2 1 4 4 4 2 Velvet factor DLH PF01738.18 KIY72790.1 - 4.4e-23 82.0 0.0 6.1e-23 81.5 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family LIDHydrolase PF10230.9 KIY72790.1 - 0.017 14.7 0.0 0.021 14.4 0.0 1.1 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Acetyltransf_10 PF13673.7 KIY72791.1 - 1.6e-07 31.3 0.0 2.3e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIY72791.1 - 1.1e-05 25.6 0.0 1.5e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KIY72791.1 - 0.0054 17.1 0.0 0.01 16.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 KIY72791.1 - 0.047 13.8 0.0 0.077 13.1 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain NmrA PF05368.13 KIY72792.1 - 3.6e-06 26.7 0.1 0.017 14.7 0.0 2.5 2 1 0 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.6 KIY72792.1 - 1.6e-05 24.9 0.7 0.0022 17.9 0.3 3.0 2 1 0 2 2 2 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 KIY72792.1 - 0.0037 17.7 0.0 0.017 15.5 0.0 2.1 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 KIY72792.1 - 0.0069 15.5 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 KIY72792.1 - 0.011 15.2 0.0 0.36 10.2 0.0 2.9 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 KIY72792.1 - 0.025 14.7 0.0 0.059 13.5 0.0 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus CoA_binding_2 PF13380.6 KIY72792.1 - 0.032 14.7 0.0 0.059 13.9 0.0 1.5 1 0 0 1 1 1 0 CoA binding domain tRNA_int_end_N2 PF12928.7 KIY72793.1 - 1.8e-15 56.9 0.0 3e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.14 KIY72793.1 - 0.038 13.7 0.0 0.068 12.8 0.0 1.4 1 0 0 1 1 1 0 tRNA intron endonuclease, N-terminal domain NAD_binding_6 PF08030.12 KIY72794.1 - 1.7e-18 67.2 0.0 5.1e-18 65.7 0.0 1.8 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 KIY72794.1 - 3.1e-18 66.1 12.4 3.1e-18 66.1 12.4 2.7 2 1 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KIY72794.1 - 1.2e-16 60.7 0.0 2.8e-16 59.6 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 KIY72794.1 - 0.0019 18.8 0.0 0.016 15.8 0.0 2.3 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain DUF3290 PF11694.8 KIY72794.1 - 5.5 7.0 5.5 3.6 7.6 2.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3290) Ost5 PF05251.12 KIY72794.1 - 5.5 7.3 10.5 10 6.5 1.2 3.8 3 0 0 3 3 3 0 Oligosaccharyltransferase subunit 5 Elong_Iki1 PF10483.9 KIY72796.1 - 2.7e-16 59.9 0.0 6.4e-16 58.7 0.0 1.6 1 1 0 1 1 1 1 Elongator subunit Iki1 BIR PF00653.21 KIY72797.1 - 1.4e-31 108.9 8.3 8.1e-16 58.4 0.6 2.4 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain zinc_ribbon_9 PF14369.6 KIY72797.1 - 2 8.7 3.6 23 5.3 0.5 2.8 2 0 0 2 2 2 0 zinc-ribbon LSM PF01423.22 KIY72799.1 - 1.9e-16 59.5 0.2 2.3e-16 59.2 0.2 1.1 1 0 0 1 1 1 1 LSM domain Acetyltransf_1 PF00583.25 KIY72800.1 - 9.5e-14 51.6 0.1 1.2e-13 51.3 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KIY72800.1 - 2.2e-12 47.0 0.0 3.1e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KIY72800.1 - 1.1e-09 38.5 0.1 1.7e-09 38.0 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIY72800.1 - 2e-05 24.5 0.0 3.9e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 KIY72800.1 - 9.8e-05 22.5 0.0 0.00013 22.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KIY72800.1 - 0.0017 18.4 0.0 0.0028 17.7 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KIY72800.1 - 0.012 15.7 0.0 0.019 15.1 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_15 PF17013.5 KIY72800.1 - 0.11 11.9 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Putative acetyl-transferase RIO1 PF01163.22 KIY72801.1 - 8.5e-47 159.2 0.0 1.7e-46 158.2 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.11 KIY72801.1 - 5.9e-34 116.1 0.1 1.4e-33 114.9 0.1 1.7 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.23 KIY72801.1 - 9e-10 38.9 0.1 0.00028 20.9 0.0 2.9 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KIY72801.1 - 1.1e-06 28.1 0.1 1e-05 25.0 0.0 2.3 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Paf1 PF03985.13 KIY72801.1 - 0.0008 18.5 8.5 0.0015 17.7 8.5 1.4 1 0 0 1 1 1 1 Paf1 CobT PF06213.12 KIY72801.1 - 0.097 12.0 14.8 0.18 11.2 14.8 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT TrmB PF01978.19 KIY72801.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB CAC1F_C PF16885.5 KIY72801.1 - 0.16 11.6 13.1 0.24 11.0 13.1 1.2 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term GNAT_acetyltr_2 PF13718.6 KIY72801.1 - 0.27 10.6 2.7 0.57 9.6 2.7 1.5 1 0 0 1 1 1 0 GNAT acetyltransferase 2 Nop14 PF04147.12 KIY72801.1 - 0.57 8.3 12.4 0.9 7.7 12.4 1.2 1 0 0 1 1 1 0 Nop14-like family PI3K_1B_p101 PF10486.9 KIY72801.1 - 1.2 6.8 6.7 1.9 6.2 6.7 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit NOA36 PF06524.12 KIY72801.1 - 1.3 8.2 12.0 2.2 7.5 12.0 1.3 1 0 0 1 1 1 0 NOA36 protein Ribosomal_60s PF00428.19 KIY72801.1 - 1.4 9.5 17.3 3.8 8.2 17.3 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein Plasmodium_Vir PF05795.11 KIY72801.1 - 2.5 7.4 5.2 3.7 6.9 5.2 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SMN PF06003.12 KIY72801.1 - 3.5 6.8 8.1 0.11 11.7 1.9 1.6 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) DUF4746 PF15928.5 KIY72801.1 - 5.9 6.2 12.5 11 5.3 12.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) CPSF100_C PF13299.6 KIY72801.1 - 7.6 6.7 10.0 0.33 11.1 3.7 1.8 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal SMN PF06003.12 KIY72802.1 - 3.8e-09 36.2 2.1 5.7e-09 35.6 2.1 1.3 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) Relaxase PF03432.14 KIY72802.1 - 0.00094 18.9 2.0 0.0015 18.2 2.0 1.3 1 0 0 1 1 1 1 Relaxase/Mobilisation nuclease domain TUDOR PF00567.24 KIY72802.1 - 0.0028 17.7 0.0 0.0063 16.5 0.0 1.6 1 1 0 1 1 1 1 Tudor domain TSSC4 PF15264.6 KIY72802.1 - 0.011 16.0 2.3 0.02 15.2 0.7 2.0 1 1 1 2 2 2 0 Tumour suppressing sub-chromosomal transferable candidate 4 DUF4537 PF15057.6 KIY72802.1 - 0.021 14.8 0.1 0.054 13.5 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4537) Sec62 PF03839.16 KIY72802.1 - 2.9 7.3 6.7 4.5 6.7 6.7 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Pil1 PF13805.6 KIY72803.1 - 1.4e-48 165.7 0.6 4e-48 164.2 0.2 1.7 2 0 0 2 2 2 1 Eisosome component PIL1 IF4E PF01652.18 KIY72804.1 - 8e-50 168.7 0.0 1e-49 168.3 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Mito_carr PF00153.27 KIY72805.1 - 5.2e-57 189.8 4.8 2.1e-19 69.3 0.3 3.5 2 2 1 3 3 3 3 Mitochondrial carrier protein PX PF00787.24 KIY72806.1 - 1e-13 51.2 0.0 2e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 PX domain Nucleoporin_FG PF13634.6 KIY72806.1 - 0.18 12.7 2.7 0.22 12.4 1.4 1.8 2 0 0 2 2 2 0 Nucleoporin FG repeat region HABP4_PAI-RBP1 PF04774.15 KIY72807.1 - 7.9e-11 42.8 13.2 7.9e-11 42.8 13.2 2.6 2 1 1 3 3 3 1 Hyaluronan / mRNA binding family Stm1_N PF09598.10 KIY72807.1 - 6.9e-06 26.8 6.0 6.9e-06 26.8 6.0 4.9 3 3 1 4 4 4 1 Stm1 Keratin_2_head PF16208.5 KIY72807.1 - 2.5 8.2 18.8 4 7.6 2.9 2.3 2 0 0 2 2 2 0 Keratin type II head PHD PF00628.29 KIY72809.1 - 2.6e-12 46.4 5.5 2.8e-12 46.3 5.5 1.0 1 0 0 1 1 1 1 PHD-finger PHD_4 PF16866.5 KIY72809.1 - 0.0019 18.2 4.6 0.0026 17.8 4.6 1.3 1 0 0 1 1 1 1 PHD-finger PhnA_Zn_Ribbon PF08274.12 KIY72809.1 - 0.041 13.8 6.0 1.3 9.0 0.1 2.3 2 0 0 2 2 2 0 PhnA Zinc-Ribbon zf-RING_9 PF13901.6 KIY72809.1 - 0.098 12.6 2.3 0.1 12.5 2.3 1.1 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon Prok-RING_1 PF14446.6 KIY72809.1 - 0.7 9.9 10.4 0.12 12.3 3.3 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 LSM PF01423.22 KIY72810.1 - 4.5e-19 67.9 0.1 6.6e-19 67.4 0.1 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 KIY72810.1 - 0.0036 16.9 0.0 0.0059 16.2 0.0 1.3 1 0 0 1 1 1 1 Hfq protein Sas10_Utp3 PF04000.15 KIY72811.1 - 2.1e-12 47.5 0.1 3.7e-12 46.7 0.1 1.4 1 0 0 1 1 1 1 Sas10/Utp3/C1D family GCV_H PF01597.19 KIY72812.1 - 6.6e-38 129.4 0.1 8.8e-38 128.9 0.1 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein RnfC_N PF13375.6 KIY72812.1 - 0.0014 18.6 0.1 0.0023 17.8 0.1 1.3 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain Biotin_lipoyl PF00364.22 KIY72812.1 - 0.0024 17.7 0.1 0.0044 16.8 0.1 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme ESSS PF10183.9 KIY72813.1 - 1.6e-13 50.8 0.0 1.7e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) CBS PF00571.28 KIY72814.1 - 6.9e-21 74.5 2.6 1.2e-09 38.4 0.1 4.4 4 0 0 4 4 4 4 CBS domain SPRY PF00622.28 KIY72815.1 - 7.2e-20 71.3 0.0 1.3e-19 70.5 0.0 1.4 1 0 0 1 1 1 1 SPRY domain Ac81 PF05820.11 KIY72815.1 - 6.9 6.2 5.3 10 5.6 5.3 1.1 1 0 0 1 1 1 0 Baculoviridae AC81 Insulin_TMD PF17870.1 KIY72816.1 - 0.042 13.9 0.1 2 8.5 0.1 2.2 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment MFS_1 PF07690.16 KIY72816.1 - 0.048 12.6 0.0 0.053 12.4 0.0 1.0 1 0 0 1 1 1 0 Major Facilitator Superfamily Ferric_reduct PF01794.19 KIY72816.1 - 0.11 12.7 0.0 0.13 12.4 0.0 1.1 1 0 0 1 1 1 0 Ferric reductase like transmembrane component tRNA-synt_2 PF00152.20 KIY72817.1 - 9.1e-78 261.5 0.0 1.3e-77 261.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KIY72817.1 - 9.9e-06 25.5 0.0 2.2e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KIY72817.1 - 0.036 13.5 0.7 1.3 8.5 0.0 2.5 2 1 0 2 2 2 0 tRNA synthetases class II core domain (F) Aminotran_1_2 PF00155.21 KIY72818.1 - 6.5e-88 295.3 0.0 7.3e-88 295.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Esterase_phd PF10503.9 KIY72820.1 - 9.6e-22 77.6 0.2 1.3e-21 77.1 0.2 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 KIY72820.1 - 9.3e-06 25.3 0.2 1.3e-05 24.8 0.2 1.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family Med5 PF08689.10 KIY72821.1 - 4.1e-08 31.6 1.7 3.9e-07 28.3 0.1 2.7 3 0 0 3 3 3 2 Mediator complex subunit Med5 Pex14_N PF04695.13 KIY72822.1 - 2.4e-17 64.0 1.3 2.4e-17 64.0 1.3 7.8 5 3 0 5 5 5 1 Peroxisomal membrane anchor protein (Pex14p) conserved region GRIP PF01465.20 KIY72822.1 - 4.8e-16 58.4 0.7 1.4e-15 56.9 0.7 1.9 1 0 0 1 1 1 1 GRIP domain ATG16 PF08614.11 KIY72822.1 - 0.011 15.9 21.4 0.011 15.9 21.4 5.8 2 1 2 5 5 5 0 Autophagy protein 16 (ATG16) Fez1 PF06818.15 KIY72822.1 - 1.4 9.3 84.8 0.16 12.4 27.5 5.6 2 1 3 5 5 5 0 Fez1 GTP_EFTU PF00009.27 KIY72823.1 - 4.4e-57 192.8 0.1 7e-57 192.1 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KIY72823.1 - 6.9e-26 90.7 0.1 1.4e-25 89.7 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KIY72823.1 - 1.1e-17 64.1 3.2 2.8e-17 62.9 3.2 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KIY72823.1 - 0.0001 22.3 0.0 0.00021 21.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIY72823.1 - 0.016 15.1 0.1 0.038 13.9 0.0 1.6 2 0 0 2 2 2 0 RsgA GTPase cobW PF02492.19 KIY72823.1 - 0.017 14.7 0.9 0.026 14.1 0.0 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 KIY72823.1 - 0.017 14.9 0.4 6.4 6.5 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Pkinase PF00069.25 KIY72824.1 - 3.7e-53 180.6 0.0 4.2e-52 177.1 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY72824.1 - 1.7e-25 89.8 0.0 3e-25 89.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DCP2 PF05026.13 KIY72826.1 - 2.6e-31 107.8 1.5 4.2e-31 107.1 1.5 1.4 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 KIY72826.1 - 6.2e-17 61.9 0.0 1.3e-16 60.8 0.0 1.5 2 0 0 2 2 2 1 NUDIX domain zf-CHCC PF10276.9 KIY72829.1 - 7.5e-13 48.3 0.5 1.1e-12 47.7 0.5 1.2 1 0 0 1 1 1 1 Zinc-finger domain SPO11_like PF03533.14 KIY72830.1 - 0.056 13.5 6.1 1.5 9.0 0.1 4.1 3 1 0 3 3 3 0 SPO11 homologue MPC PF03650.13 KIY72833.1 - 1.5e-34 118.4 0.1 1.8e-34 118.2 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers LIM PF00412.22 KIY72835.1 - 2.4e-12 46.9 28.4 9.9e-06 25.7 4.5 5.8 5 1 0 5 5 5 4 LIM domain Cytochrome_C7 PF14522.6 KIY72835.1 - 0.0057 16.6 1.4 0.0057 16.6 1.4 3.0 3 1 0 3 3 3 1 Cytochrome c7 and related cytochrome c FMN_dh PF01070.18 KIY72836.1 - 1.9e-104 349.5 0.0 2.2e-104 349.2 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KIY72836.1 - 1.3e-19 70.1 0.0 2.3e-19 69.3 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 KIY72836.1 - 2.3e-06 27.0 0.1 5.6e-06 25.7 0.1 1.6 1 1 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KIY72836.1 - 0.00091 18.3 0.3 0.0031 16.6 0.2 1.8 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 KIY72836.1 - 0.0041 16.6 0.0 0.0065 15.9 0.0 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.14 KIY72836.1 - 0.09 12.1 0.2 1.5 8.1 0.0 2.2 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG Importin_rep_2 PF18786.1 KIY72836.1 - 0.94 9.4 3.3 0.51 10.2 0.4 2.1 3 0 0 3 3 3 0 Importin 13 repeat Rho_N PF07498.12 KIY72837.1 - 0.071 13.1 0.1 0.14 12.1 0.1 1.5 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain DUF1043 PF06295.12 KIY72837.1 - 0.077 13.0 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF4054 PF13262.6 KIY72837.1 - 0.083 12.9 0.4 0.2 11.7 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4054) DnaJ PF00226.31 KIY72838.1 - 2.9e-19 69.0 3.2 4.5e-19 68.3 3.2 1.3 1 0 0 1 1 1 1 DnaJ domain SNF2_N PF00176.23 KIY72839.1 - 1.5e-64 218.0 0.3 1.5e-64 218.0 0.3 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain DBINO PF13892.6 KIY72839.1 - 8.8e-46 155.6 19.9 8.8e-46 155.6 19.9 1.9 2 0 0 2 2 2 1 DNA-binding domain Helicase_C PF00271.31 KIY72839.1 - 9.4e-18 64.6 0.0 2.2e-17 63.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIY72839.1 - 1.7e-07 31.4 0.7 4.1e-07 30.2 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KIY72839.1 - 1e-05 24.9 3.8 0.00023 20.5 0.0 2.9 3 0 0 3 3 3 2 Class II histone deacetylase complex subunits 2 and 3 PhoH PF02562.16 KIY72839.1 - 0.0034 16.8 0.0 0.0063 16.0 0.0 1.3 1 0 0 1 1 1 1 PhoH-like protein Lyase_1 PF00206.20 KIY72840.1 - 1.5e-120 402.3 0.0 2e-120 401.9 0.0 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 KIY72840.1 - 1.9e-21 76.2 0.1 4.2e-21 75.1 0.1 1.6 1 0 0 1 1 1 1 Fumarase C C-terminus PEX11 PF05648.14 KIY72841.1 - 2.1e-51 174.5 0.8 2.4e-51 174.4 0.8 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Cmc1 PF08583.10 KIY72842.1 - 8.8e-10 38.5 1.6 1.1e-09 38.2 1.6 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like COX17 PF05051.13 KIY72842.1 - 0.019 15.3 2.9 0.079 13.3 0.1 2.1 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) LIAS_N PF16881.5 KIY72843.1 - 8.9e-25 87.2 0.1 6.3e-24 84.5 0.0 2.1 2 0 0 2 2 2 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 KIY72843.1 - 2.1e-15 57.5 0.0 5e-15 56.3 0.0 1.7 1 0 0 1 1 1 1 Radical SAM superfamily Glyco_transf_8 PF01501.20 KIY72844.1 - 1.6e-23 83.6 0.0 2.2e-23 83.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 8 Glyco_transf_24 PF18404.1 KIY72844.1 - 0.001 18.6 0.1 0.0017 17.8 0.1 1.2 1 0 0 1 1 1 1 Glucosyltransferase 24 Glyco_transf_21 PF13506.6 KIY72844.1 - 0.11 12.0 0.5 0.27 10.7 0.4 1.6 1 1 1 2 2 2 0 Glycosyl transferase family 21 Mannosyl_trans3 PF11051.8 KIY72844.1 - 0.18 11.1 0.0 0.29 10.5 0.0 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative Peptidase_M22 PF00814.25 KIY72845.1 - 3.5e-84 282.7 0.0 4.1e-84 282.5 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 KIY72845.1 - 0.032 13.9 0.0 0.74 9.4 0.0 2.1 2 0 0 2 2 2 0 Carbamoyltransferase N-terminus BTV_NS2 PF04514.12 KIY72846.1 - 0.12 11.2 2.0 0.19 10.6 2.0 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 MT PF12777.7 KIY72846.1 - 0.68 8.9 5.5 0.24 10.4 1.7 1.8 1 1 1 2 2 2 0 Microtubule-binding stalk of dynein motor V_ATPase_I PF01496.19 KIY72846.1 - 1.3 6.8 7.8 1.8 6.4 7.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FapA PF03961.13 KIY72846.1 - 3.6 6.1 9.0 3.8 6.0 8.1 1.5 1 1 0 1 1 1 0 Flagellar Assembly Protein A Prominin PF05478.11 KIY72846.1 - 5.5 4.8 8.3 8 4.3 8.3 1.1 1 0 0 1 1 1 0 Prominin 2-oxoacid_dh PF00198.23 KIY72847.1 - 1.9e-78 263.2 0.0 2.4e-78 262.8 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KIY72847.1 - 5.2e-20 71.1 0.3 1.5e-19 69.5 0.3 1.9 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 KIY72847.1 - 2.9e-13 49.9 0.3 7.7e-13 48.6 0.3 1.8 1 0 0 1 1 1 1 e3 binding domain DUF3614 PF12267.8 KIY72847.1 - 0.053 14.0 0.0 0.18 12.3 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3614) Biotin_lipoyl_2 PF13533.6 KIY72847.1 - 0.068 13.0 0.0 0.21 11.4 0.0 1.9 1 0 0 1 1 1 0 Biotin-lipoyl like Ribosomal_60s PF00428.19 KIY72847.1 - 1.1 9.9 16.6 1.3 9.6 8.1 2.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein EXOSC1 PF10447.9 KIY72848.1 - 9.4e-18 64.8 2.7 8e-13 49.0 0.6 2.2 1 1 1 2 2 2 2 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 KIY72848.1 - 0.00028 20.6 0.0 0.00074 19.3 0.0 1.7 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region Es2 PF09751.9 KIY72849.1 - 2.4e-78 264.8 5.9 6.3e-78 263.4 5.9 1.7 1 1 0 1 1 1 1 Nuclear protein Es2 SLX9 PF15341.6 KIY72850.1 - 8e-15 55.4 12.5 1.2e-14 54.8 12.5 1.3 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 Tox-ODYAM1 PF15642.6 KIY72850.1 - 0.007 15.4 1.6 0.0079 15.2 1.6 1.1 1 0 0 1 1 1 1 Toxin in Odyssella and Amoebophilus EamA PF00892.20 KIY72851.1 - 9.4e-09 35.6 40.6 0.00068 19.8 15.7 2.9 2 1 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 KIY72851.1 - 0.017 14.5 16.1 0.049 13.0 16.1 1.8 1 1 0 1 1 1 0 Triose-phosphate Transporter family Internalin_N PF12354.8 KIY72851.1 - 0.27 11.4 1.5 9.5 6.4 0.0 3.2 2 1 1 3 3 3 0 Bacterial adhesion/invasion protein N terminal GCP_N_terminal PF17681.1 KIY72852.1 - 1.4e-43 149.7 0.0 2e-43 149.2 0.0 1.2 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 KIY72852.1 - 1.7e-27 96.7 0.0 4.4e-27 95.4 0.0 1.6 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP5-Mod21 PF14609.6 KIY72852.1 - 0.00079 17.9 0.7 0.0015 16.9 0.3 1.7 2 0 0 2 2 2 1 gamma-Tubulin ring complex non-core subunit mod21 PBP1_TM PF14812.6 KIY72852.1 - 0.17 12.3 5.1 0.56 10.6 5.1 1.9 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Spt5_N PF11942.8 KIY72852.1 - 9.5 7.3 13.9 17 6.5 1.2 2.8 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Adap_comp_sub PF00928.21 KIY72853.1 - 1.2e-43 149.4 0.0 1.5e-43 149.1 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KIY72853.1 - 0.00012 22.0 0.0 0.00021 21.2 0.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Melibiase_2 PF16499.5 KIY72854.1 - 2.9e-57 194.0 3.1 4.6e-57 193.3 3.1 1.3 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 KIY72854.1 - 1.5e-12 47.4 0.1 4.2e-12 46.0 0.1 1.8 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 KIY72854.1 - 0.0035 16.4 0.0 0.0055 15.7 0.0 1.2 1 0 0 1 1 1 1 Melibiase SLS PF14611.6 KIY72855.1 - 1.9e-09 37.7 0.0 3e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator eIF2A PF08662.11 KIY72856.1 - 1.2e-40 139.5 1.1 2.6e-37 128.6 0.2 4.6 3 2 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 KIY72856.1 - 5.8e-09 35.6 0.1 1.3e-08 34.5 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 KIY72856.1 - 0.011 16.6 1.8 1.1 10.2 0.0 4.5 6 0 0 6 6 6 0 WD domain, G-beta repeat Hap4_Hap_bind PF10297.9 KIY72857.1 - 5.2e-06 26.4 7.9 5.2e-06 26.4 7.9 2.5 2 0 0 2 2 2 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.21 KIY72857.1 - 0.00014 21.9 21.0 0.00053 20.0 17.9 2.6 1 1 0 1 1 1 1 bZIP transcription factor HAUS-augmin3 PF14932.6 KIY72857.1 - 0.0016 18.0 3.6 0.0026 17.4 3.6 1.3 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 3 ZapB PF06005.12 KIY72857.1 - 0.0089 16.4 11.1 0.018 15.4 11.1 1.5 1 0 0 1 1 1 1 Cell division protein ZapB NUDE_C PF04880.13 KIY72857.1 - 0.019 15.5 14.8 0.019 15.5 14.8 3.2 3 2 0 3 3 3 0 NUDE protein, C-terminal conserved region bZIP_2 PF07716.15 KIY72857.1 - 0.065 13.3 21.9 0.039 14.0 3.3 2.9 3 0 0 3 3 3 0 Basic region leucine zipper DUF572 PF04502.13 KIY72857.1 - 0.17 11.4 9.3 0.26 10.9 9.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) YabA PF06156.13 KIY72857.1 - 0.19 12.4 5.8 0.38 11.4 5.8 1.5 1 0 0 1 1 1 0 Initiation control protein YabA Fungal_TACC PF12709.7 KIY72857.1 - 0.28 11.6 3.2 0.31 11.5 2.2 1.5 1 1 0 1 1 1 0 Fungal Transforming acidic coiled-coil (TACC) proteins Seadorna_VP6 PF07407.11 KIY72857.1 - 0.32 9.9 0.8 0.48 9.3 0.8 1.1 1 0 0 1 1 1 0 Seadornavirus VP6 protein GAS PF13851.6 KIY72857.1 - 0.99 8.7 11.4 1.5 8.1 11.4 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Macoilin PF09726.9 KIY72857.1 - 1.3 7.5 9.9 1.8 7.0 9.9 1.2 1 0 0 1 1 1 0 Macoilin family PV-1 PF06637.11 KIY72857.1 - 2 7.2 9.3 3 6.6 9.3 1.2 1 0 0 1 1 1 0 PV-1 protein (PLVAP) Bud13 PF09736.9 KIY72857.1 - 2.3 8.6 10.7 3.6 8.0 10.7 1.3 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex HALZ PF02183.18 KIY72857.1 - 4.3 7.6 7.4 0.36 11.1 2.4 1.8 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF4407 PF14362.6 KIY72857.1 - 5.3 6.3 8.9 8.4 5.7 8.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) bZIP_Maf PF03131.17 KIY72857.1 - 5.4 7.6 16.7 1.8 9.1 11.9 2.2 1 1 1 2 2 2 0 bZIP Maf transcription factor Uso1_p115_C PF04871.13 KIY72857.1 - 7.5 6.9 13.7 12 6.2 13.7 1.3 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region PPR_2 PF13041.6 KIY72858.1 - 6.9e-26 90.2 0.0 2.6e-08 33.9 0.0 6.6 4 1 2 6 6 6 6 PPR repeat family PPR_3 PF13812.6 KIY72858.1 - 1.1e-18 67.1 0.0 4.5e-09 36.2 0.0 5.7 4 1 0 5 5 5 3 Pentatricopeptide repeat domain PPR_1 PF12854.7 KIY72858.1 - 8.6e-18 63.7 0.1 4e-08 32.8 0.0 4.8 5 0 0 5 5 5 3 PPR repeat PPR PF01535.20 KIY72858.1 - 8.5e-15 53.9 0.8 4.5e-06 26.6 0.0 5.6 6 0 0 6 6 6 3 PPR repeat PPR_long PF17177.4 KIY72858.1 - 9.2e-14 51.3 0.0 1.1e-07 31.4 0.0 3.7 3 1 0 3 3 3 2 Pentacotripeptide-repeat region of PRORP Prp19 PF08606.11 KIY72858.1 - 0.045 13.7 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 Prp19/Pso4-like DUF3863 PF12979.7 KIY72858.1 - 0.049 12.5 0.0 0.086 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3863) RPM2 PF08579.11 KIY72858.1 - 0.052 13.9 0.0 4.9 7.6 0.0 3.7 4 0 0 4 4 4 0 Mitochondrial ribonuclease P subunit (RPM2) ECSIT PF06239.11 KIY72858.1 - 0.13 11.4 0.0 0.82 8.7 0.0 2.2 2 0 0 2 2 2 0 Evolutionarily conserved signalling intermediate in Toll pathway TPR_14 PF13428.6 KIY72858.1 - 9.6 7.3 9.2 19 6.4 0.1 5.2 6 1 1 7 7 7 0 Tetratricopeptide repeat AMP-binding PF00501.28 KIY72859.1 - 3.8e-18 65.3 0.0 6.1e-16 58.0 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme GH3 PF03321.13 KIY72859.1 - 0.037 12.9 0.0 0.063 12.1 0.0 1.3 1 0 0 1 1 1 0 GH3 auxin-responsive promoter Rad51 PF08423.11 KIY72860.1 - 3.6e-06 26.4 0.0 8e-06 25.3 0.0 1.5 1 1 0 1 1 1 1 Rad51 AAA_25 PF13481.6 KIY72860.1 - 0.002 17.7 0.0 0.0033 17.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KIY72860.1 - 0.04 13.6 0.0 0.055 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KIY72860.1 - 0.063 13.8 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 ABC transporter RsgA_GTPase PF03193.16 KIY72860.1 - 0.12 12.3 0.1 0.34 10.8 0.0 1.7 2 0 0 2 2 2 0 RsgA GTPase IER PF05760.12 KIY72860.1 - 0.17 12.2 0.2 9.2 6.5 0.1 2.1 1 1 0 2 2 2 0 Immediate early response protein (IER) Cep57_CLD_2 PF14197.6 KIY72861.1 - 0.0092 16.0 8.8 0.0092 16.0 8.8 4.3 5 0 0 5 5 5 1 Centrosome localisation domain of PPC89 Aminopep PF10023.9 KIY72861.1 - 0.62 9.4 7.7 1.1 8.5 7.7 1.4 1 0 0 1 1 1 0 Putative aminopeptidase DUF1664 PF07889.12 KIY72861.1 - 3.3 7.8 7.5 1.6 8.8 3.4 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) CLZ PF16526.5 KIY72861.1 - 6.4 7.2 19.9 0.1 13.0 3.6 4.4 3 1 1 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ATG16 PF08614.11 KIY72861.1 - 6.9 6.8 39.2 1.8 8.8 10.2 3.5 3 1 1 4 4 4 0 Autophagy protein 16 (ATG16) HAUS-augmin3 PF14932.6 KIY72861.1 - 7 6.1 26.8 2.8 7.4 10.1 2.9 3 0 0 3 3 3 0 HAUS augmin-like complex subunit 3 YabA PF06156.13 KIY72861.1 - 8.1 7.2 16.7 9.1 7.0 0.1 4.3 3 1 0 3 3 3 0 Initiation control protein YabA ZapB PF06005.12 KIY72861.1 - 9.8 6.7 34.8 0.3 11.5 1.8 5.1 3 2 2 5 5 5 0 Cell division protein ZapB Spb1_C PF07780.12 KIY72862.1 - 1.9e-79 266.2 18.0 1.9e-79 266.2 18.0 3.0 4 0 0 4 4 4 1 Spb1 C-terminal domain FtsJ PF01728.19 KIY72862.1 - 4.9e-57 192.9 0.0 3.8e-56 190.0 0.0 2.2 2 0 0 2 2 2 1 FtsJ-like methyltransferase DUF3381 PF11861.8 KIY72862.1 - 2e-47 161.1 4.4 2e-47 161.1 4.4 5.1 4 2 1 5 5 5 1 Domain of unknown function (DUF3381) DUF3464 PF11947.8 KIY72862.1 - 0.21 11.3 0.1 0.21 11.3 0.1 2.7 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 DUF423 PF04241.15 KIY72863.1 - 1.9e-18 66.4 2.4 2.8e-18 65.9 2.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF423) Ras PF00071.22 KIY72865.1 - 9.5e-55 184.6 0.0 1.1e-54 184.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIY72865.1 - 1.2e-21 77.1 0.0 1.6e-21 76.7 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIY72865.1 - 3e-06 26.8 0.0 4.1e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KIY72865.1 - 0.0081 15.7 0.0 0.034 13.7 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain ETRAMP PF09716.10 KIY72866.1 - 0.096 12.8 0.0 1 9.5 0.0 2.4 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Fungal_trans PF04082.18 KIY72867.1 - 5.3e-10 38.8 0.1 1e-09 37.8 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY72867.1 - 1.7e-07 31.3 10.8 3.4e-07 30.3 10.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UBM PF14377.6 KIY72867.1 - 0.22 11.0 2.0 0.23 11.0 0.1 2.1 2 0 0 2 2 2 0 Ubiquitin binding region PDT PF00800.18 KIY72868.1 - 1.8e-53 181.1 0.0 2.7e-53 180.5 0.0 1.3 1 0 0 1 1 1 1 Prephenate dehydratase zf-CCCH PF00642.24 KIY72869.1 - 2.6e-15 55.9 24.7 1.9e-05 24.4 0.6 4.9 4 1 1 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KIY72869.1 - 1.2e-13 50.6 29.5 1e-06 28.6 2.1 4.8 5 0 0 5 5 5 4 Zinc finger domain Torus PF16131.5 KIY72869.1 - 2.2e-08 34.8 21.2 0.00034 21.3 0.3 4.6 1 1 4 5 5 5 4 Torus domain zf-CCCH_4 PF18044.1 KIY72869.1 - 2.5e-05 24.0 0.4 2.5e-05 24.0 0.4 5.3 6 0 0 6 6 6 2 CCCH-type zinc finger zf-CCHC PF00098.23 KIY72869.1 - 0.00036 20.5 3.7 0.00036 20.5 3.7 2.3 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_3 PF13917.6 KIY72869.1 - 0.0039 17.1 0.2 0.011 15.7 0.2 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 KIY72869.1 - 0.053 13.2 0.9 0.053 13.2 0.9 3.2 3 0 0 3 3 3 0 GAG-polyprotein viral zinc-finger zf-CCCH_2 PF14608.6 KIY72869.1 - 0.055 14.0 30.7 0.065 13.7 0.3 5.3 5 0 0 5 5 5 0 RNA-binding, Nab2-type zinc finger TRP_N PF14558.6 KIY72869.1 - 2.1 8.7 3.4 35 4.7 0.1 2.3 2 0 0 2 2 2 0 ML-like domain zf-CCCH_3 PF15663.5 KIY72869.1 - 2.7 8.3 18.2 2.5 8.3 0.5 3.9 1 1 2 4 4 4 0 Zinc-finger containing family p450 PF00067.22 KIY72870.1 - 2.7e-71 240.7 0.0 3.3e-71 240.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 polyprenyl_synt PF00348.17 KIY72871.1 - 3.3e-92 308.2 0.0 4.1e-92 307.8 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase RhoGEF PF00621.20 KIY72873.1 - 2.3e-14 54.1 0.0 4e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain Sod_Fe_C PF02777.18 KIY72874.1 - 8.2e-18 64.5 0.0 8.5e-09 35.5 0.0 2.5 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain DUF1845 PF08900.11 KIY72874.1 - 0.052 13.3 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1845) FUSC_2 PF13515.6 KIY72874.1 - 0.14 12.3 0.4 0.27 11.4 0.4 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein-like GN3L_Grn1 PF08701.11 KIY72874.1 - 0.37 10.9 1.1 0.79 9.9 1.1 1.4 1 0 0 1 1 1 0 GNL3L/Grn1 putative GTPase Hexokinase_2 PF03727.16 KIY72875.1 - 7.3e-75 251.5 0.0 1.1e-74 250.9 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KIY72875.1 - 1e-70 237.7 0.0 1.5e-70 237.2 0.0 1.2 1 0 0 1 1 1 1 Hexokinase UPF0270 PF06794.12 KIY72875.1 - 0.012 15.7 0.0 0.097 12.8 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0270) DAD PF02109.16 KIY72877.1 - 4.1e-49 165.4 1.3 4.6e-49 165.3 1.3 1.0 1 0 0 1 1 1 1 DAD family DUF1748 PF08520.10 KIY72878.1 - 3.6e-24 84.4 0.0 4.3e-24 84.2 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) Cellulase PF00150.18 KIY72879.1 - 7.9e-18 64.9 0.0 1.1e-17 64.4 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Mt_ATP-synt_D PF05873.12 KIY72880.1 - 5.5e-11 42.5 0.3 7e-11 42.2 0.3 1.2 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) MS_channel PF00924.18 KIY72882.1 - 2e-21 76.5 0.1 3.1e-21 75.9 0.1 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 KIY72882.1 - 0.00035 19.9 0.2 0.0022 17.4 0.0 2.3 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 KIY72882.1 - 0.0005 19.8 0.2 0.011 15.6 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 KIY72882.1 - 0.012 15.1 0.1 0.029 13.9 0.1 1.7 1 0 0 1 1 1 0 EF hand PBP1_TM PF14812.6 KIY72882.1 - 0.031 14.6 2.4 0.27 11.7 0.3 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal EF-hand_7 PF13499.6 KIY72882.1 - 0.086 13.3 0.3 0.26 11.7 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain pair LSM PF01423.22 KIY72885.1 - 1.1e-20 73.0 0.0 1.3e-20 72.9 0.0 1.0 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 KIY72885.1 - 0.023 14.3 0.0 0.033 13.8 0.0 1.3 1 1 0 1 1 1 0 Hfq protein SM-ATX PF14438.6 KIY72885.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain PPR_3 PF13812.6 KIY72886.1 - 0.013 15.6 0.0 3.6 7.7 0.0 3.1 3 0 0 3 3 3 0 Pentatricopeptide repeat domain PPR_2 PF13041.6 KIY72886.1 - 0.036 14.3 0.0 49 4.2 0.0 3.6 3 0 0 3 3 3 0 PPR repeat family SYS1 PF09801.9 KIY72887.1 - 1.2e-25 90.3 8.4 7.5e-17 61.8 8.0 2.1 2 0 0 2 2 2 2 Integral membrane protein S linking to the trans Golgi network DUF3397 PF11877.8 KIY72887.1 - 0.0094 16.1 2.0 0.021 15.0 2.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3397) RRS1 PF04939.12 KIY72888.1 - 2.4e-58 196.6 4.5 4.1e-58 195.8 4.5 1.4 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) ThiF PF00899.21 KIY72889.1 - 1.1e-13 51.1 0.0 1.4e-12 47.5 0.0 2.0 1 1 0 1 1 1 1 ThiF family TFIIB PF00382.19 KIY72890.1 - 1.2e-37 127.7 0.1 3e-21 75.3 0.2 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 KIY72890.1 - 1.6e-12 46.7 0.7 2.4e-12 46.1 0.7 1.3 1 0 0 1 1 1 1 TFIIB zinc-binding RB_B PF01857.20 KIY72890.1 - 0.00054 20.0 0.2 0.0053 16.8 0.2 2.1 2 0 0 2 2 2 1 Retinoblastoma-associated protein B domain Cyclin_N PF00134.23 KIY72890.1 - 0.0031 17.3 0.1 0.0049 16.6 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Guanylin PF02058.15 KIY72890.1 - 0.029 14.8 3.1 15 6.1 0.1 3.1 1 1 2 3 3 3 0 Guanylin precursor HTH_38 PF13936.6 KIY72890.1 - 0.04 13.7 0.0 0.32 10.8 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain zinc_ribbon_10 PF10058.9 KIY72890.1 - 0.064 13.0 0.0 0.18 11.6 0.0 1.8 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein MT-A70 PF05063.14 KIY72891.1 - 2.5e-56 190.3 0.1 3.5e-56 189.8 0.1 1.2 1 0 0 1 1 1 1 MT-A70 Hydantoinase_A PF01968.18 KIY72893.1 - 2e-97 326.0 0.0 3.9e-97 325.0 0.0 1.5 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KIY72893.1 - 1.9e-59 200.4 0.4 1.7e-56 190.7 0.0 2.3 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region DUF1275 PF06912.11 KIY72894.1 - 6.4e-28 98.0 16.5 7.8e-28 97.7 16.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) p450 PF00067.22 KIY72895.1 - 8.3e-55 186.3 0.0 2e-54 185.1 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 SWI-SNF_Ssr4 PF08549.10 KIY72897.1 - 5.7e-25 88.1 8.1 3.3e-19 69.0 0.0 2.4 3 0 0 3 3 3 2 Fungal domain of unknown function (DUF1750) BRD4_CDT PF17105.5 KIY72897.1 - 0.31 10.7 9.0 0.6 9.7 9.0 1.5 1 0 0 1 1 1 0 C-terminal domain of bromodomain protein 4 SlyX PF04102.12 KIY72897.1 - 0.61 10.7 9.1 11 6.8 7.1 2.4 2 0 0 2 2 2 0 SlyX Egh16-like PF11327.8 KIY72900.1 - 7.4e-40 137.3 4.7 7.4e-40 137.3 4.7 2.4 2 1 0 2 2 2 1 Egh16-like virulence factor FAM199X PF15814.5 KIY72900.1 - 8.6 5.3 14.7 0.11 11.5 3.6 2.4 2 0 0 2 2 2 0 Protein family FAM199X HbrB PF08539.11 KIY72901.1 - 2.9e-52 177.1 0.0 5e-52 176.3 0.0 1.4 1 0 0 1 1 1 1 HbrB-like Ten_N PF06484.12 KIY72903.1 - 0.11 12.4 5.9 0.15 11.9 5.9 1.1 1 0 0 1 1 1 0 Teneurin Intracellular Region C2 PF00168.30 KIY72904.1 - 1.1e-24 86.6 0.0 7.4e-13 48.7 0.0 2.6 2 0 0 2 2 2 2 C2 domain Cul7 PF11515.8 KIY72904.1 - 0.069 13.4 0.3 0.16 12.3 0.3 1.6 1 0 0 1 1 1 0 Mouse development and cellular proliferation protein Cullin-7 Dehydrin PF00257.19 KIY72904.1 - 3.7 8.1 5.7 0.69 10.5 1.0 2.0 2 0 0 2 2 2 0 Dehydrin FA_hydroxylase PF04116.13 KIY72905.1 - 1.9e-22 80.1 14.7 1.9e-22 80.1 14.7 2.2 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily SNARE_assoc PF09335.11 KIY72905.1 - 0.065 13.7 0.2 7.5 7.1 0.0 2.5 2 1 0 2 2 2 0 SNARE associated Golgi protein 2TM PF13239.6 KIY72905.1 - 0.59 10.5 6.0 4.5 7.6 0.1 2.5 2 0 0 2 2 2 0 2TM domain SOR_SNZ PF01680.17 KIY72906.1 - 9.3e-107 355.5 7.9 1.4e-106 354.8 7.9 1.3 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 KIY72906.1 - 4.3e-08 32.8 7.4 5.6e-07 29.1 0.1 2.5 2 1 0 2 2 2 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 KIY72906.1 - 3.2e-05 23.2 0.4 0.057 12.5 0.1 2.5 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 KIY72906.1 - 0.0002 20.9 0.2 0.024 14.1 0.0 3.0 2 1 0 2 2 2 1 Histidine biosynthesis protein TetR_C_27 PF17935.1 KIY72906.1 - 0.00054 20.0 0.0 0.0019 18.3 0.0 1.9 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain NanE PF04131.14 KIY72906.1 - 0.0012 18.1 0.5 0.026 13.7 0.0 2.4 2 0 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase DUF188 PF02639.14 KIY72906.1 - 0.014 15.0 0.0 0.028 14.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized BCR, YaiI/YqxD family COG1671 IGPS PF00218.21 KIY72906.1 - 0.019 14.1 0.0 0.14 11.3 0.0 2.1 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase NMO PF03060.15 KIY72906.1 - 0.024 14.0 0.2 0.024 14.0 0.2 2.2 2 0 0 2 2 2 0 Nitronate monooxygenase Dus PF01207.17 KIY72907.1 - 1.6e-50 172.0 0.0 2.6e-50 171.3 0.0 1.3 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) zf-CCCH_4 PF18044.1 KIY72907.1 - 0.0014 18.4 8.7 0.39 10.6 0.1 2.7 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH PF00642.24 KIY72907.1 - 0.048 13.6 7.7 0.57 10.2 3.0 2.5 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 KIY72907.1 - 1.1 9.9 6.0 3.5 8.2 0.2 2.7 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger Torus PF16131.5 KIY72907.1 - 3.3 8.4 5.3 16 6.2 0.1 2.7 3 0 0 3 3 3 0 Torus domain FUSC_2 PF13515.6 KIY72908.1 - 3.6e-17 62.7 11.8 3.6e-17 62.7 11.8 2.7 2 0 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.8 KIY72908.1 - 4e-11 42.4 5.6 2.1e-09 36.8 3.4 2.3 2 0 0 2 2 2 2 Aluminium activated malate transporter FUSC PF04632.12 KIY72908.1 - 6.9e-11 41.4 17.0 4.3e-10 38.8 10.0 2.6 2 0 0 2 2 2 2 Fusaric acid resistance protein family ArAE_2 PF10334.9 KIY72908.1 - 4.1e-09 36.6 0.2 5e-07 29.8 0.0 2.4 2 0 0 2 2 2 2 Aromatic acid exporter family member 2 FUSC-like PF12805.7 KIY72908.1 - 0.00015 20.9 2.8 0.17 10.9 0.8 2.6 2 0 0 2 2 2 2 FUSC-like inner membrane protein yccS Zn_clus PF00172.18 KIY72909.1 - 1.5e-07 31.4 7.4 1.5e-07 31.4 7.4 2.7 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-H2C2_2 PF13465.6 KIY72909.1 - 1.1e-06 28.8 5.3 0.00012 22.4 2.4 2.9 2 0 0 2 2 2 2 Zinc-finger double domain Fungal_trans PF04082.18 KIY72909.1 - 5.5e-06 25.6 0.1 2.5e-05 23.5 0.1 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KIY72909.1 - 0.012 16.1 18.2 0.026 15.0 3.0 3.1 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KIY72909.1 - 0.045 13.8 4.2 5.1 7.2 1.0 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger TehB PF03848.14 KIY72909.1 - 0.12 11.8 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB zf-met PF12874.7 KIY72909.1 - 0.16 12.4 10.8 0.2 12.1 1.3 3.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KIY72909.1 - 0.18 12.7 15.9 0.17 12.8 2.4 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KIY72909.1 - 7 7.1 8.7 5.5 7.4 0.5 3.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Oxidored_FMN PF00724.20 KIY72910.1 - 1.4e-99 333.6 0.0 1.8e-99 333.3 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family His_biosynth PF00977.21 KIY72910.1 - 0.025 14.0 0.0 0.042 13.3 0.0 1.2 1 0 0 1 1 1 0 Histidine biosynthesis protein DnaJ_CXXCXGXG PF00684.19 KIY72911.1 - 0.00041 20.7 4.6 0.17 12.3 0.4 2.3 2 0 0 2 2 2 2 DnaJ central domain Nucleoporin_FG2 PF15967.5 KIY72911.1 - 1.2 7.5 3.4 1.7 7.1 3.4 1.1 1 0 0 1 1 1 0 Nucleoporin FG repeated region Adaptin_N PF01602.20 KIY72913.1 - 4.9e-108 362.0 3.2 6.5e-108 361.6 3.2 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KIY72913.1 - 6.2e-12 45.9 0.7 3.2e-07 30.5 0.0 3.6 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KIY72913.1 - 4.2e-07 29.7 1.9 0.22 11.9 0.0 4.6 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.6 KIY72913.1 - 2.1e-06 28.0 7.4 0.0021 18.4 0.0 4.1 4 1 1 5 5 5 2 HEAT repeats RTP1_C1 PF10363.9 KIY72913.1 - 0.00032 20.8 1.2 0.2 11.9 0.0 3.3 3 0 0 3 3 3 2 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 KIY72913.1 - 0.00082 19.8 7.0 0.1 13.1 0.0 5.4 6 0 0 6 6 6 1 HEAT-like repeat V-ATPase_H_C PF11698.8 KIY72913.1 - 0.0081 16.3 3.8 4.2 7.5 0.0 3.7 3 1 0 3 3 3 2 V-ATPase subunit H Cnd3 PF12719.7 KIY72913.1 - 0.064 12.4 0.1 2.2 7.4 0.1 2.4 1 1 0 1 1 1 0 Nuclear condensing complex subunits, C-term domain Proteasom_PSMB PF10508.9 KIY72913.1 - 0.091 11.3 2.2 0.94 7.9 0.4 2.9 2 2 0 2 2 2 0 Proteasome non-ATPase 26S subunit Peptidase_M28 PF04389.17 KIY72914.1 - 1.7e-29 103.0 0.1 2.7e-29 102.3 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KIY72914.1 - 2.5e-08 33.9 0.0 5.1e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Ribosomal_L11 PF00298.19 KIY72915.1 - 1.7e-28 99.0 0.1 2.7e-28 98.2 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.14 KIY72915.1 - 9e-24 83.1 0.3 1.4e-23 82.5 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Glyco_hydro_cc PF11790.8 KIY72918.1 - 2.3e-54 184.5 4.6 3.9e-54 183.8 4.6 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core DUF5114 PF17141.4 KIY72918.1 - 0.05 14.1 0.3 0.13 12.8 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5114) RRM_1 PF00076.22 KIY72920.1 - 1.7e-28 98.2 0.0 6.3e-13 48.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.15 KIY72920.1 - 0.00098 19.1 0.1 1 9.4 0.0 2.4 2 0 0 2 2 2 2 DbpA RNA binding domain SLC12 PF03522.15 KIY72920.1 - 0.81 8.6 3.4 1.1 8.2 3.4 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Presenilin PF01080.17 KIY72920.1 - 0.99 8.1 6.2 1.3 7.7 6.2 1.2 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.10 KIY72920.1 - 2.3 6.8 6.3 2.6 6.6 6.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Raftlin PF15250.6 KIY72920.1 - 3.8 6.2 7.4 5.2 5.7 7.4 1.2 1 0 0 1 1 1 0 Raftlin OB_RNB PF08206.11 KIY72920.1 - 9.5 6.0 6.7 51 3.7 0.0 3.7 3 1 0 3 3 3 0 Ribonuclease B OB domain DUF4187 PF13821.6 KIY72921.1 - 1.4e-21 76.0 2.1 3.3e-21 74.8 2.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.23 KIY72921.1 - 1.5e-06 28.0 1.1 1.5e-05 24.8 1.1 2.3 1 1 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KIY72921.1 - 0.00022 21.2 0.4 0.00088 19.3 0.4 2.0 1 1 0 1 1 1 1 G-patch domain DUF3425 PF11905.8 KIY72925.1 - 1.3e-15 57.5 0.4 1.8e-14 53.8 0.2 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 KIY72925.1 - 1.8e-07 31.2 4.3 1.8e-07 31.2 4.3 2.7 2 1 1 3 3 3 2 bZIP transcription factor bZIP_2 PF07716.15 KIY72925.1 - 0.00052 20.0 8.5 0.0037 17.3 3.4 2.6 2 0 0 2 2 2 2 Basic region leucine zipper DUF5101 PF17031.5 KIY72925.1 - 0.015 15.4 0.1 0.033 14.3 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5101) PKcGMP_CC PF16808.5 KIY72925.1 - 0.058 13.3 1.0 0.14 12.0 1.0 1.7 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Ribosomal_S14 PF00253.21 KIY72926.1 - 2.4e-19 68.9 0.6 4.3e-19 68.0 0.6 1.4 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e MFS_1 PF07690.16 KIY72927.1 - 4.6e-42 144.2 48.1 4.4e-38 131.1 49.1 3.4 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIY72927.1 - 8.8e-11 41.3 8.2 8.8e-11 41.3 8.2 3.2 3 0 0 3 3 3 2 Sugar (and other) transporter TPPK_C PF12555.8 KIY72927.1 - 6.1 7.0 9.6 5.1 7.2 0.3 4.2 3 1 1 4 4 4 0 Thiamine pyrophosphokinase C terminal WD40 PF00400.32 KIY72928.1 - 5.7e-07 30.1 0.9 0.95 10.5 0.0 4.6 4 0 0 4 4 4 2 WD domain, G-beta repeat Glyco_hydro_125 PF06824.11 KIY72929.1 - 1.1e-152 508.7 0.1 1.3e-152 508.5 0.1 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) ADH_N PF08240.12 KIY72930.1 - 8.4e-21 73.9 2.1 1.9e-20 72.8 2.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KIY72930.1 - 7.2e-18 64.8 1.0 1.3e-17 64.0 0.2 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KIY72930.1 - 0.0026 17.2 0.1 0.0045 16.4 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KIY72930.1 - 0.025 13.9 0.3 0.049 12.9 0.3 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ThiF PF00899.21 KIY72930.1 - 0.061 12.7 0.8 0.45 9.8 0.7 2.1 2 0 0 2 2 2 0 ThiF family CLLAC PF15675.5 KIY72930.1 - 8.6 6.0 6.3 0.55 9.8 0.8 1.8 2 0 0 2 2 2 0 CLLAC-motif containing domain Vfa1 PF08432.10 KIY72931.1 - 3.1e-37 128.6 11.5 3.5e-37 128.5 11.5 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 DUF908 PF06012.12 KIY72931.1 - 0.0042 16.6 5.8 0.0044 16.5 5.8 1.1 1 0 0 1 1 1 1 Domain of Unknown Function (DUF908) CDC45 PF02724.14 KIY72931.1 - 0.036 12.4 6.3 0.039 12.3 6.3 1.0 1 0 0 1 1 1 0 CDC45-like protein ANAPC_CDC26 PF10471.9 KIY72931.1 - 0.054 14.3 9.4 0.054 14.3 9.4 2.4 3 0 0 3 3 2 0 Anaphase-promoting complex APC subunit CDC26 FAM83 PF07894.12 KIY72931.1 - 0.14 11.7 4.4 0.17 11.4 4.4 1.2 1 0 0 1 1 1 0 FAM83 A-H CCDC53 PF10152.9 KIY72931.1 - 0.22 12.0 7.9 0.32 11.4 7.9 1.4 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF913 PF06025.12 KIY72931.1 - 0.32 9.9 3.4 0.35 9.8 3.4 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SRP-alpha_N PF04086.13 KIY72931.1 - 0.32 10.9 13.2 0.39 10.6 13.2 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF3824 PF12868.7 KIY72931.1 - 0.64 10.7 18.1 1.2 9.8 18.1 1.4 1 1 0 1 1 1 0 Domain of unknwon function (DUF3824) Peptidase_S49_N PF08496.10 KIY72931.1 - 1.5 8.9 9.4 0.11 12.5 4.0 1.7 2 0 0 2 2 2 0 Peptidase family S49 N-terminal RR_TM4-6 PF06459.12 KIY72931.1 - 1.9 8.3 14.6 2.3 7.9 14.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Endostatin PF06482.11 KIY72931.1 - 2.1 7.7 7.0 2.4 7.6 7.0 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Hid1 PF12722.7 KIY72931.1 - 3.9 5.5 11.4 4.7 5.2 11.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein FAM60A PF15396.6 KIY72931.1 - 5.8 6.9 12.4 7.7 6.5 12.4 1.1 1 0 0 1 1 1 0 Protein Family FAM60A PIEZO PF15917.5 KIY72931.1 - 6.1 6.3 12.0 8.1 5.9 12.0 1.1 1 0 0 1 1 1 0 Piezo PA26 PF04636.13 KIY72931.1 - 6.4 5.6 6.8 7.4 5.4 6.8 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Zip PF02535.22 KIY72931.1 - 7.4 5.7 5.8 8.4 5.5 5.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 KIY72931.1 - 9.1 4.9 12.4 11 4.7 12.4 1.1 1 0 0 1 1 1 0 Presenilin DUF1744 PF08490.12 KIY72932.1 - 1.9e-127 425.1 0.0 2.9e-127 424.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 KIY72932.1 - 1.8e-73 247.6 0.0 2.8e-73 247.0 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 KIY72932.1 - 1e-12 47.5 0.4 2.1e-10 39.9 0.4 3.8 2 1 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 KIY72932.1 - 3.8e-09 36.5 0.7 1.1e-08 35.1 0.2 2.0 2 1 0 2 2 2 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 KIY72932.1 - 0.00015 21.8 0.0 0.00058 19.9 0.0 2.1 1 0 0 1 1 1 1 RNase_H superfamily DUF2244 PF10003.9 KIY72933.1 - 4.6 6.9 6.4 12 5.5 3.5 2.4 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) C2 PF00168.30 KIY72935.1 - 1.4e-13 51.0 0.0 5.4e-10 39.5 0.0 2.3 2 0 0 2 2 2 2 C2 domain NifU_N PF01592.16 KIY72936.1 - 4.3e-53 178.9 0.1 9.2e-52 174.6 0.0 2.0 1 1 1 2 2 2 2 NifU-like N terminal domain Pkinase PF00069.25 KIY72937.1 - 1.2e-65 221.5 0.0 3e-65 220.2 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY72937.1 - 3.6e-30 105.1 0.0 1.3e-28 100.1 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY72937.1 - 7.8e-05 22.1 0.5 0.044 13.1 0.2 2.3 2 0 0 2 2 2 2 Kinase-like RIO1 PF01163.22 KIY72937.1 - 0.008 15.8 0.3 0.012 15.2 0.3 1.2 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 KIY72937.1 - 0.035 12.9 0.0 0.049 12.4 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 KIY72937.1 - 0.051 13.5 0.0 0.76 9.6 0.0 2.2 1 1 0 2 2 2 0 Phosphotransferase enzyme family Glyco_hydro_45 PF02015.16 KIY72938.1 - 1.5e-77 260.3 19.3 1.8e-77 260.0 19.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 Nop PF01798.18 KIY72939.1 - 9.4e-72 241.2 0.0 1.4e-71 240.6 0.0 1.3 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 KIY72939.1 - 7e-35 120.6 6.7 1.6e-34 119.4 6.7 1.6 1 0 0 1 1 1 1 Prp31 C terminal domain SNARE_assoc PF09335.11 KIY72940.1 - 9.6e-10 39.0 10.2 1e-09 38.9 8.5 1.9 2 1 0 2 2 2 1 SNARE associated Golgi protein DUF1772 PF08592.11 KIY72940.1 - 3.4 8.0 6.7 85 3.5 6.8 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1772) Tctex-1 PF03645.13 KIY72941.1 - 1.1e-11 44.9 0.2 1.5e-11 44.4 0.2 1.3 1 1 0 1 1 1 1 Tctex-1 family PEX11 PF05648.14 KIY72942.1 - 6.1e-16 58.6 1.6 4.4e-07 29.6 0.1 2.1 2 0 0 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) Pkinase PF00069.25 KIY72943.1 - 3.2e-71 239.8 0.0 4.3e-71 239.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY72943.1 - 3e-28 98.8 0.1 1.7e-26 93.1 0.1 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY72943.1 - 3.9e-09 36.2 1.0 3e-05 23.5 0.0 2.8 2 1 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 KIY72943.1 - 4.3e-05 22.5 0.6 0.00027 19.8 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 KIY72943.1 - 0.047 13.0 0.0 0.08 12.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIY72943.1 - 0.13 12.2 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family HSF_DNA-bind PF00447.17 KIY72944.1 - 2.4e-18 66.5 0.0 4.5e-18 65.7 0.0 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Ets PF00178.22 KIY72944.1 - 0.052 14.0 0.0 0.1 13.1 0.0 1.5 1 0 0 1 1 1 0 Ets-domain DOPA_dioxygen PF08883.11 KIY72946.1 - 1.1e-26 93.1 0.0 1.4e-26 92.7 0.0 1.2 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family WD40 PF00400.32 KIY72947.1 - 3.1e-06 27.8 1.8 0.015 16.1 0.0 4.1 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY72947.1 - 0.0044 17.3 0.0 6.8 7.1 0.0 3.4 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Mg_trans_NIPA PF05653.14 KIY72948.1 - 1.5e-60 204.8 11.7 9.5e-58 195.6 7.7 2.0 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 KIY72948.1 - 0.003 17.7 3.5 0.003 17.7 3.5 3.2 3 0 0 3 3 3 1 EamA-like transporter family SLC35F PF06027.12 KIY72948.1 - 0.2 11.1 5.8 0.7 9.3 5.8 1.8 1 1 0 1 1 1 0 Solute carrier family 35 VMA21 PF09446.10 KIY72948.1 - 0.35 11.0 4.1 0.37 10.9 1.6 2.3 2 0 0 2 2 2 0 VMA21-like domain DUF3185 PF11381.8 KIY72948.1 - 0.39 10.8 2.5 23 5.1 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3185) F-box-like PF12937.7 KIY72949.1 - 1.8e-07 30.9 1.2 3.6e-07 30.0 0.0 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIY72949.1 - 0.11 12.4 2.7 4.1 7.4 0.2 2.9 2 0 0 2 2 2 0 F-box domain COX16 PF14138.6 KIY72951.1 - 9.7e-28 96.5 0.0 1.2e-27 96.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 ACBP PF00887.19 KIY72952.1 - 1.5e-22 79.6 0.2 2.6e-22 78.8 0.2 1.4 1 0 0 1 1 1 1 Acyl CoA binding protein EAP30 PF04157.16 KIY72953.1 - 4.6e-70 235.6 0.0 5.2e-70 235.4 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family Rap_GAP PF02145.15 KIY72954.1 - 3.4e-43 147.3 0.0 5.6e-43 146.6 0.0 1.3 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.16 KIY72954.1 - 2.9e-36 125.3 2.7 6.9e-33 114.2 1.3 2.2 2 0 0 2 2 2 2 Tuberin DUF3384 PF11864.8 KIY72954.1 - 2.2e-07 30.1 0.5 0.0097 14.9 0.0 3.6 4 0 0 4 4 4 2 Domain of unknown function (DUF3384) DUF2235 PF09994.9 KIY72955.1 - 4.2e-87 292.1 0.0 5.4e-87 291.8 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) DNA_pol_D_N PF18018.1 KIY72957.1 - 2e-43 147.6 0.0 3e-43 147.0 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain DNA_pol_E_B PF04042.16 KIY72957.1 - 1.3e-26 93.3 0.0 1.8e-26 92.8 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Elong-fact-P_C PF09285.11 KIY72957.1 - 0.22 11.3 0.5 5 7.0 0.0 2.5 2 0 0 2 2 2 0 Elongation factor P, C-terminal Peptidase_C2 PF00648.21 KIY72958.1 - 1.1e-63 215.0 0.0 9.4e-63 212.0 0.0 2.1 1 1 0 1 1 1 1 Calpain family cysteine protease ANAPC10 PF03256.16 KIY72958.1 - 0.031 13.9 0.0 0.055 13.1 0.0 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex, subunit 10 (APC10) Nop14 PF04147.12 KIY72958.1 - 1.3 7.1 12.9 2.1 6.4 12.9 1.2 1 0 0 1 1 1 0 Nop14-like family Senescence PF06911.12 KIY72960.1 - 5.3e-43 147.5 2.9 1.1e-42 146.5 2.9 1.5 1 1 0 1 1 1 1 Senescence-associated protein Tau95 PF09734.9 KIY72961.1 - 8.3e-39 133.6 0.6 8.3e-39 133.6 0.6 2.7 3 1 0 3 3 3 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 KIY72961.1 - 1.1e-23 83.8 0.1 2.8e-23 82.5 0.1 1.7 1 0 0 1 1 1 1 Tau95 Triple barrel domain Ribosomal_L29e PF01779.17 KIY72962.1 - 1.4e-21 76.5 11.2 1.9e-21 76.1 11.2 1.2 1 0 0 1 1 1 1 Ribosomal L29e protein family SDA1 PF05285.12 KIY72963.1 - 0.067 12.6 8.9 0.12 11.8 8.9 1.4 1 0 0 1 1 1 0 SDA1 Vma12 PF11712.8 KIY72963.1 - 1.6 8.8 3.0 12 5.9 1.1 2.4 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Lin-8 PF03353.15 KIY72963.1 - 2 7.9 13.3 0.19 11.3 8.1 1.7 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist FHA PF00498.26 KIY72964.1 - 3.2e-16 59.4 0.0 6.6e-16 58.4 0.0 1.6 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KIY72964.1 - 0.00095 19.4 0.0 0.0028 17.9 0.0 1.8 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain Zn_clus PF00172.18 KIY72965.1 - 1.5e-06 28.2 10.2 2.3e-06 27.6 10.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KIY72965.1 - 6.4e-06 25.4 0.0 1.1e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 KIY72966.1 - 4.1e-41 141.1 21.0 4.1e-41 141.1 21.0 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Trp_oprn_chp PF09534.10 KIY72966.1 - 0.00042 20.2 4.9 0.049 13.4 2.7 2.9 2 1 0 2 2 2 2 Tryptophan-associated transmembrane protein (Trp_oprn_chp) MT-A70 PF05063.14 KIY72967.1 - 8.1e-37 126.8 0.0 1.7e-36 125.7 0.0 1.4 1 1 0 1 1 1 1 MT-A70 N6-adenineMlase PF10237.9 KIY72967.1 - 0.043 13.6 0.0 0.066 13.0 0.0 1.2 1 0 0 1 1 1 0 Probable N6-adenine methyltransferase Cons_hypoth95 PF03602.15 KIY72967.1 - 0.17 11.6 0.1 0.27 10.8 0.1 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Gpi16 PF04113.14 KIY72968.1 - 4.7e-132 441.3 0.0 1.7e-130 436.1 0.0 2.0 1 1 0 1 1 1 1 Gpi16 subunit, GPI transamidase component COX15-CtaA PF02628.15 KIY72969.1 - 4.8e-112 374.2 5.1 5.9e-112 373.9 5.1 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein BolA PF01722.18 KIY72970.1 - 9.1e-13 48.3 0.0 2.8e-12 46.7 0.0 1.7 1 1 0 1 1 1 1 BolA-like protein Methyltransf_16 PF10294.9 KIY72971.1 - 2.6e-45 154.2 0.0 3.6e-45 153.8 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 KIY72971.1 - 0.0032 16.9 0.0 0.0046 16.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KIY72971.1 - 0.0032 17.0 0.0 0.0049 16.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 KIY72971.1 - 0.049 14.3 0.0 0.087 13.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 KIY72971.1 - 0.1 12.4 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Nitroreductase PF00881.24 KIY72973.1 - 6.8e-12 45.8 0.1 8.3e-12 45.5 0.1 1.1 1 0 0 1 1 1 1 Nitroreductase family U3snoRNP10 PF12397.8 KIY72973.1 - 0.091 13.1 0.0 0.63 10.4 0.0 1.9 2 0 0 2 2 2 0 U3 small nucleolar RNA-associated protein 10 AMPK1_CBM PF16561.5 KIY72974.1 - 1.4e-22 79.7 0.3 2.2e-22 79.0 0.3 1.2 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase RNB PF00773.19 KIY72976.1 - 7.7e-98 327.8 0.0 1.2e-97 327.2 0.0 1.2 1 0 0 1 1 1 1 RNB domain Rrp44_CSD1 PF17216.3 KIY72976.1 - 1.3e-23 83.3 0.1 3.3e-23 82.1 0.1 1.7 1 0 0 1 1 1 1 Rrp44-like cold shock domain Rrp44_S1 PF17215.3 KIY72976.1 - 1.2e-22 79.6 1.4 2.6e-22 78.6 1.4 1.6 1 0 0 1 1 1 1 S1 domain OB_Dis3 PF17849.1 KIY72976.1 - 5.8e-16 58.3 0.0 3.8e-15 55.7 0.0 2.5 3 0 0 3 3 3 1 Dis3-like cold-shock domain 2 (CSD2) PIN_4 PF13638.6 KIY72976.1 - 6.9e-10 39.3 0.0 6.9e-10 39.3 0.0 2.1 3 0 0 3 3 3 1 PIN domain CSD2 PF17876.1 KIY72976.1 - 7.9e-08 32.4 3.7 0.00029 20.9 0.0 4.9 5 0 0 5 5 5 1 Cold shock domain OB_RNB PF08206.11 KIY72976.1 - 0.46 10.2 1.6 4.6 7.0 0.1 2.8 2 0 0 2 2 2 0 Ribonuclease B OB domain Nitroreductase PF00881.24 KIY72977.1 - 6.1e-15 55.7 0.0 7.3e-15 55.4 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family Proteasome PF00227.26 KIY72978.1 - 1.6e-53 181.0 0.0 2e-53 180.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KIY72978.1 - 6.4e-13 48.1 1.7 1.1e-12 47.3 0.1 2.1 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature GTP_cyclohydroI PF01227.22 KIY72979.1 - 1.4e-74 249.4 0.6 1.9e-74 249.0 0.6 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 KIY72979.1 - 0.00017 21.7 0.0 0.00061 19.9 0.0 1.9 2 0 0 2 2 2 1 QueF-like protein HATPase_c_2 PF13581.6 KIY72979.1 - 0.08 12.9 0.1 0.16 11.9 0.1 1.4 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain ABC_tran PF00005.27 KIY72980.1 - 5.7e-26 91.7 0.0 1e-25 90.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KIY72980.1 - 7.1e-08 32.6 0.8 0.0095 15.8 0.1 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KIY72980.1 - 1.6e-06 27.7 0.1 3.8e-05 23.2 0.1 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_13 PF13166.6 KIY72980.1 - 3e-06 26.2 0.1 0.0011 17.7 0.0 2.1 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 KIY72980.1 - 0.00024 20.9 0.5 0.14 11.8 0.1 2.1 2 0 0 2 2 2 2 AAA ATPase domain SbcCD_C PF13558.6 KIY72980.1 - 0.0036 17.5 0.0 0.0098 16.1 0.0 1.7 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_24 PF13479.6 KIY72980.1 - 0.0037 17.0 0.0 0.0068 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KIY72980.1 - 0.0072 15.6 0.0 0.021 14.1 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin AAA_29 PF13555.6 KIY72980.1 - 0.012 15.4 0.0 0.031 14.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF87 PF01935.17 KIY72980.1 - 0.052 13.6 0.0 0.097 12.7 0.0 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_23 PF13476.6 KIY72980.1 - 0.055 14.0 0.0 0.093 13.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KIY72980.1 - 0.063 13.4 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KIY72980.1 - 0.088 13.2 0.0 0.67 10.4 0.0 2.4 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KIY72980.1 - 0.14 12.5 0.0 2.6 8.3 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 KIY72980.1 - 0.17 12.4 0.0 0.39 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 KIY72980.1 - 0.19 11.6 0.0 0.35 10.8 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase Ank_2 PF12796.7 KIY72981.1 - 8.4e-64 212.2 7.2 2.1e-18 66.7 0.1 4.5 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KIY72981.1 - 3.8e-30 103.8 9.0 3.5e-12 46.6 0.1 5.2 4 1 2 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIY72981.1 - 9.5e-26 87.0 9.5 3.5e-06 26.9 0.1 7.0 7 0 0 7 7 7 5 Ankyrin repeat SPX PF03105.19 KIY72981.1 - 1.3e-25 91.1 10.7 3.4e-09 37.1 0.0 3.2 1 1 2 3 3 3 3 SPX domain Ank PF00023.30 KIY72981.1 - 7.6e-24 83.1 10.0 1.4e-05 25.3 0.2 6.9 6 0 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.6 KIY72981.1 - 1e-21 76.7 11.4 7.1e-07 29.4 0.1 7.2 1 1 6 7 7 7 7 Ankyrin repeats (many copies) GDPD PF03009.17 KIY72981.1 - 2.1e-15 57.2 0.0 4.4e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family DnaJ PF00226.31 KIY72982.1 - 9.4e-11 41.7 0.6 4.1e-10 39.6 0.0 2.5 2 0 0 2 2 2 1 DnaJ domain zf-CCCH_4 PF18044.1 KIY72982.1 - 1.4e-10 40.7 16.7 1.3e-06 28.1 3.2 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger Ank_4 PF13637.6 KIY72982.1 - 4.1e-10 40.0 0.1 1.9e-08 34.7 0.1 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIY72982.1 - 3.3e-08 33.2 0.1 0.17 12.5 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat zf-CCCH PF00642.24 KIY72982.1 - 4e-08 33.0 10.8 0.0002 21.1 1.1 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Ank_2 PF12796.7 KIY72982.1 - 4.6e-08 33.5 0.0 8.5e-07 29.5 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) zf_CCCH_4 PF18345.1 KIY72982.1 - 1.2e-05 25.2 23.9 3.1e-05 23.9 6.1 2.5 2 0 0 2 2 2 2 Zinc finger domain Ank PF00023.30 KIY72982.1 - 3.3e-05 24.1 0.7 3.3 8.3 0.1 3.5 3 0 0 3 3 3 2 Ankyrin repeat Torus PF16131.5 KIY72982.1 - 0.00025 21.7 0.1 0.00025 21.7 0.1 4.8 4 2 0 5 5 4 2 Torus domain zf-CCCH_2 PF14608.6 KIY72982.1 - 0.001 19.5 14.5 0.0053 17.2 1.9 2.5 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger Ank_5 PF13857.6 KIY72982.1 - 0.0028 17.9 1.6 1.8 9.0 0.0 3.2 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Glyco_hydro_88 PF07470.13 KIY72983.1 - 1.1e-18 67.5 1.7 1.6e-18 66.9 1.7 1.2 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 THOC2_N PF16134.5 KIY72984.1 - 3.7e-133 445.4 0.0 6.4e-133 444.6 0.0 1.3 1 0 0 1 1 1 1 THO complex subunit 2 N-terminus Tho2 PF11262.8 KIY72984.1 - 9.1e-80 268.1 0.1 1.4e-79 267.5 0.1 1.3 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.8 KIY72984.1 - 9.1e-20 70.5 0.0 2.2e-19 69.3 0.0 1.7 1 0 0 1 1 1 1 Transcription- and export-related complex subunit GTP_EFTU PF00009.27 KIY72985.1 - 1.1e-35 122.9 0.0 1.5e-35 122.5 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KIY72985.1 - 5.5e-16 58.9 0.1 5.8e-15 55.6 0.0 2.5 2 1 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KIY72985.1 - 0.00018 21.8 0.1 0.00038 20.8 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KIY72985.1 - 0.00029 20.9 0.0 0.00049 20.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 KIY72985.1 - 0.033 13.8 0.0 0.051 13.2 0.0 1.2 1 0 0 1 1 1 0 Ras family GTP_EFTU_D4 PF14578.6 KIY72985.1 - 0.059 13.3 0.1 0.15 12.0 0.1 1.6 1 0 0 1 1 1 0 Elongation factor Tu domain 4 SSB PF00436.25 KIY72987.1 - 2.9e-18 65.8 0.0 3.6e-18 65.5 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family N_formyltrans_C PF18216.1 KIY72987.1 - 0.049 13.3 0.1 0.081 12.6 0.1 1.3 1 0 0 1 1 1 0 N-formyltransferase dimerization C-terminal domain Haem_degrading PF03928.14 KIY72988.1 - 6.5e-09 35.9 0.1 1.7e-08 34.5 0.1 1.7 1 1 0 1 1 1 1 Haem-degrading Pex2_Pex12 PF04757.14 KIY72989.1 - 5.4e-47 160.3 3.2 6.3e-47 160.0 3.2 1.0 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 KIY72989.1 - 1.4e-06 28.1 1.4 2e-06 27.5 1.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KIY72989.1 - 1.1e-05 25.2 2.6 1.7e-05 24.6 2.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIY72989.1 - 0.00073 19.8 2.3 0.0012 19.2 2.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KIY72989.1 - 0.0013 18.7 3.3 0.0024 17.8 3.3 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KIY72989.1 - 0.0027 17.5 3.3 0.0042 16.9 3.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KIY72989.1 - 0.0031 17.6 3.8 0.005 17.0 3.8 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING PI3K_p85B PF02192.16 KIY72989.1 - 0.046 13.5 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 PI3-kinase family, p85-binding domain zf-piccolo PF05715.13 KIY72989.1 - 0.066 13.4 0.6 0.11 12.6 0.6 1.3 1 0 0 1 1 1 0 Piccolo Zn-finger Prok-RING_4 PF14447.6 KIY72989.1 - 0.12 12.2 3.2 0.41 10.6 0.1 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KIY72989.1 - 8.7 6.4 6.0 89 3.2 0.4 2.1 1 1 1 2 2 2 0 zinc-RING finger domain Pectate_lyase PF03211.13 KIY72991.1 - 5.1e-90 300.5 11.6 5.9e-90 300.2 11.6 1.0 1 0 0 1 1 1 1 Pectate lyase Baculo_ME53 PF06061.11 KIY72991.1 - 0.077 12.2 0.9 0.099 11.9 0.9 1.1 1 0 0 1 1 1 0 Baculoviridae ME53 Suc_Fer-like PF06999.12 KIY72992.1 - 3.2e-52 177.3 0.0 3.9e-52 177.0 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like YhfH PF14149.6 KIY72992.1 - 0.028 14.4 1.5 0.062 13.3 1.5 1.5 1 0 0 1 1 1 0 YhfH-like protein DUF4336 PF14234.6 KIY72993.1 - 1.5e-17 63.8 0.0 2.5e-12 46.7 0.0 2.6 1 1 1 2 2 2 2 Domain of unknown function (DUF4336) GATA PF00320.27 KIY72994.1 - 1.5e-08 34.1 6.6 2.5e-08 33.4 6.6 1.4 1 0 0 1 1 1 1 GATA zinc finger Rubredoxin_2 PF18073.1 KIY72994.1 - 2.5 7.9 6.6 1.4 8.7 2.0 2.3 2 0 0 2 2 2 0 Rubredoxin metal binding domain Myb_DNA-binding PF00249.31 KIY72995.1 - 8.4e-32 109.1 9.5 2.6e-09 37.1 0.3 5.4 5 0 0 5 5 5 5 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KIY72995.1 - 3.1e-28 97.8 1.5 2.3e-06 27.7 0.1 5.4 3 2 2 5 5 5 5 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KIY72995.1 - 0.021 14.7 0.1 5 7.1 0.0 3.3 3 1 1 4 4 4 0 Myb DNA-binding like Cyanate_lyase PF02560.14 KIY72997.1 - 9.5e-34 115.1 0.0 1.4e-33 114.6 0.0 1.2 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_31 PF13560.6 KIY72997.1 - 0.0022 18.3 0.0 0.0032 17.8 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 KIY72997.1 - 0.051 13.3 0.0 0.36 10.5 0.0 2.0 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_3 PF01381.22 KIY72997.1 - 0.099 12.7 0.1 0.16 12.0 0.1 1.3 1 0 0 1 1 1 0 Helix-turn-helix Ribosomal_L3 PF00297.22 KIY72998.1 - 2.5e-186 619.0 7.0 2.8e-186 618.9 7.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 EF-hand_4 PF12763.7 KIY72999.1 - 2.6e-25 88.4 0.0 2e-13 50.2 0.0 3.5 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 KIY72999.1 - 7.7e-05 23.1 0.0 0.25 11.8 0.0 3.9 2 2 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KIY72999.1 - 0.0014 18.4 0.1 4.7 7.4 0.0 3.6 3 0 0 3 3 3 1 EF-hand domain KASH_CCD PF14662.6 KIY72999.1 - 0.025 14.4 34.7 0.074 12.9 18.9 3.5 2 1 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH Macoilin PF09726.9 KIY72999.1 - 0.17 10.4 17.5 0.29 9.6 17.5 1.3 1 0 0 1 1 1 0 Macoilin family YabA PF06156.13 KIY72999.1 - 0.97 10.1 25.1 22 5.7 1.6 4.5 1 1 2 3 3 3 0 Initiation control protein YabA DUF2353 PF09789.9 KIY72999.1 - 1.8 7.8 32.4 2.9 7.2 13.3 2.7 1 1 2 3 3 3 0 Uncharacterized coiled-coil protein (DUF2353) Ntox28 PF15605.6 KIY72999.1 - 3.2 8.0 11.1 1 9.6 0.9 3.4 2 1 1 3 3 3 0 Bacterial toxin 28 TSC22 PF01166.18 KIY72999.1 - 4.8 7.6 18.5 1.8 8.9 0.9 6.1 3 1 2 6 6 6 0 TSC-22/dip/bun family K-box PF01486.17 KIY72999.1 - 8.8 6.6 23.6 0.81 9.9 7.5 4.4 4 1 0 4 4 4 0 K-box region Ham1p_like PF01725.16 KIY73000.1 - 5.8e-56 189.4 0.0 7.2e-56 189.1 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Peptidase_M24 PF00557.24 KIY73001.1 - 4e-46 157.3 0.0 5.4e-46 156.9 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N_2 PF16189.5 KIY73001.1 - 1.1e-45 155.7 0.0 2.4e-45 154.5 0.1 1.6 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Peptidase_M24_C PF16188.5 KIY73001.1 - 2.8e-25 88.1 0.0 2.2e-24 85.3 0.0 2.5 2 0 0 2 2 2 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 KIY73001.1 - 2.3e-19 70.4 0.0 6.8e-15 55.9 0.0 2.4 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain PPR_3 PF13812.6 KIY73002.1 - 6e-08 32.6 0.0 0.026 14.6 0.0 3.7 2 1 2 4 4 4 2 Pentatricopeptide repeat domain PPR_2 PF13041.6 KIY73002.1 - 1.7e-07 31.3 0.1 0.001 19.2 0.0 4.0 3 1 1 4 4 4 3 PPR repeat family PPR_1 PF12854.7 KIY73002.1 - 3.8e-07 29.7 0.3 0.0029 17.3 0.0 3.1 3 0 0 3 3 3 2 PPR repeat PPR PF01535.20 KIY73002.1 - 5e-07 29.5 0.5 0.00077 19.6 0.0 4.7 5 0 0 5 5 5 1 PPR repeat ATP13 PF12921.7 KIY73002.1 - 0.067 13.1 0.0 0.35 10.7 0.0 2.1 1 1 1 2 2 2 0 Mitochondrial ATPase expression DUF4158 PF13700.6 KIY73002.1 - 0.13 12.1 0.1 0.3 10.9 0.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4158) Aldo_ket_red PF00248.21 KIY73004.1 - 1.1e-30 106.9 0.0 1.3e-30 106.6 0.0 1.2 1 1 0 1 1 1 1 Aldo/keto reductase family Ribosomal_S7e PF01251.18 KIY73005.1 - 1.1e-85 286.0 1.8 2e-85 285.2 1.8 1.4 1 0 0 1 1 1 1 Ribosomal protein S7e TPR_1 PF00515.28 KIY73005.1 - 3e-14 52.1 7.5 3.4e-05 23.5 0.2 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KIY73005.1 - 7.5e-10 38.2 5.6 0.0054 16.8 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 KIY73005.1 - 5.3e-06 26.8 0.1 0.00053 20.5 0.0 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KIY73005.1 - 0.00016 22.2 0.0 0.15 13.0 0.0 3.6 2 2 1 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KIY73005.1 - 0.00035 20.4 0.4 1.2 9.4 0.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 KIY73005.1 - 0.00059 19.9 1.4 0.029 14.6 0.1 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KIY73005.1 - 0.00091 19.8 0.1 0.16 12.6 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 KIY73005.1 - 0.0049 17.1 4.4 1.8 8.9 1.1 3.2 2 1 0 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KIY73005.1 - 0.0066 16.6 3.3 0.0076 16.4 1.8 2.0 2 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.17 KIY73005.1 - 0.026 14.9 0.1 0.065 13.7 0.1 1.7 1 0 0 1 1 1 0 Bacterial transcriptional activator domain TPR_17 PF13431.6 KIY73005.1 - 0.038 14.4 1.6 0.18 12.3 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TBD PF12845.7 KIY73005.1 - 0.061 13.2 0.6 3.8 7.5 0.2 2.7 2 0 0 2 2 2 0 TBD domain Fis1_TPR_C PF14853.6 KIY73005.1 - 0.079 13.0 0.1 3.2 7.9 0.0 2.6 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat Ras PF00071.22 KIY73006.1 - 4.3e-45 153.2 0.0 5.1e-42 143.2 0.0 2.2 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KIY73006.1 - 2.1e-33 115.1 0.0 3e-33 114.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIY73006.1 - 2.3e-11 43.5 0.1 5e-11 42.4 0.0 1.5 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KIY73006.1 - 3.5e-07 30.3 0.0 7.8e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KIY73006.1 - 9.7e-06 25.1 0.2 3e-05 23.5 0.0 1.8 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KIY73006.1 - 3e-05 23.5 0.0 0.00026 20.5 0.0 2.3 3 0 0 3 3 3 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 KIY73006.1 - 0.00027 20.7 0.1 0.011 15.4 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 KIY73006.1 - 0.00027 21.2 0.1 0.0039 17.5 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KIY73006.1 - 0.00032 21.1 0.0 0.0011 19.4 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 KIY73006.1 - 0.00076 19.4 0.1 0.0042 17.0 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_24 PF13479.6 KIY73006.1 - 0.0062 16.3 0.1 0.054 13.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KIY73006.1 - 0.035 13.6 0.1 0.062 12.8 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 KIY73006.1 - 0.038 14.2 0.2 2.5 8.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 KIY73006.1 - 0.09 12.2 0.0 0.19 11.1 0.0 1.5 2 0 0 2 2 2 0 Bacterial TniB protein ABC_tran PF00005.27 KIY73006.1 - 0.1 13.1 0.0 0.2 12.2 0.0 1.5 1 0 0 1 1 1 0 ABC transporter ATPase_2 PF01637.18 KIY73006.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NACHT PF05729.12 KIY73006.1 - 0.12 12.3 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.6 KIY73006.1 - 0.18 11.5 0.3 0.63 9.8 0.0 2.1 2 0 0 2 2 1 0 P-loop containing region of AAA domain Septin PF00735.18 KIY73006.1 - 0.22 10.8 0.1 0.36 10.1 0.1 1.3 1 0 0 1 1 1 0 Septin PRIMA1 PF16101.5 KIY73006.1 - 2.2 8.3 8.3 6.7 6.8 8.3 1.8 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 AMMECR1 PF01871.17 KIY73007.1 - 7.9e-44 149.2 0.0 1.9e-43 147.9 0.0 1.6 1 1 0 1 1 1 1 AMMECR1 MRC1 PF09444.10 KIY73008.1 - 5.2e-18 66.0 26.9 5.2e-18 66.0 26.9 5.8 3 2 2 6 6 6 1 MRC1-like domain Glyco_hydro_16 PF00722.21 KIY73010.1 - 1.9e-21 76.4 0.8 2.8e-21 75.8 0.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 zf-LYAR PF08790.11 KIY73011.1 - 4e-13 49.0 2.7 6.2e-13 48.4 2.7 1.3 1 0 0 1 1 1 1 LYAR-type C2HC zinc finger zf-C2H2 PF00096.26 KIY73011.1 - 0.00013 22.3 0.4 0.00064 20.0 0.3 2.0 2 1 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIY73011.1 - 0.0085 16.9 2.2 0.11 13.4 0.4 2.3 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KIY73011.1 - 0.014 15.7 0.4 0.029 14.6 0.1 1.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf_UBZ PF18439.1 KIY73011.1 - 0.02 14.5 0.3 0.35 10.5 0.1 2.2 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Muskelin_N PF06588.11 KIY73013.1 - 7.5e-50 169.6 0.0 1.1e-49 169.1 0.0 1.2 1 0 0 1 1 1 1 Muskelin N-terminus Kelch_4 PF13418.6 KIY73013.1 - 5.7e-22 77.5 5.1 5.6e-07 29.5 0.1 6.2 7 0 0 7 7 7 3 Galactose oxidase, central domain Kelch_5 PF13854.6 KIY73013.1 - 3.4e-20 71.6 0.8 2.4e-06 27.4 0.1 5.9 6 0 0 6 6 6 4 Kelch motif Kelch_3 PF13415.6 KIY73013.1 - 1.2e-16 60.5 9.5 9.8e-06 25.7 0.0 6.3 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_6 PF13964.6 KIY73013.1 - 4e-16 58.7 2.2 0.0019 18.4 0.1 5.9 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.25 KIY73013.1 - 4.1e-12 45.5 3.5 3.9e-05 23.1 0.1 6.0 6 0 0 6 6 6 3 Kelch motif F5_F8_type_C PF00754.25 KIY73013.1 - 0.0021 18.2 0.0 0.0042 17.2 0.0 1.5 1 0 0 1 1 1 1 F5/8 type C domain Sad1_UNC PF07738.13 KIY73013.1 - 0.032 14.2 0.0 0.058 13.4 0.0 1.3 1 0 0 1 1 1 0 Sad1 / UNC-like C-terminal ArsC PF03960.15 KIY73014.1 - 0.045 13.8 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 ArsC family zf-C2H2 PF00096.26 KIY73015.1 - 1.6e-09 37.7 28.0 3.5e-05 24.0 3.3 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 KIY73015.1 - 0.00065 19.4 14.9 0.066 13.0 5.8 3.4 3 0 0 3 3 3 2 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 KIY73015.1 - 0.00085 20.0 32.1 0.0081 16.9 3.3 4.1 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 KIY73015.1 - 0.015 15.4 0.1 0.015 15.4 0.1 1.9 1 1 1 2 2 2 0 Aberrant zinc-finger zf-met PF12874.7 KIY73015.1 - 0.045 14.2 6.1 0.85 10.1 0.2 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 KIY73015.1 - 0.062 13.8 2.8 0.062 13.8 2.8 4.1 4 0 0 4 4 4 0 Zinc-finger double domain zf-MYST PF17772.1 KIY73015.1 - 1.3 8.7 0.0 1.3 8.7 0.0 2.8 3 0 0 3 3 3 0 MYST family zinc finger domain RNA_pol_Rbc25 PF08292.12 KIY73016.1 - 1.2e-31 109.7 0.0 1.9e-31 109.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 KIY73016.1 - 1.1e-18 67.4 0.1 1.8e-18 66.7 0.1 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 zf-rbx1 PF12678.7 KIY73017.1 - 1.2e-10 41.5 0.8 7e-09 35.8 0.2 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KIY73017.1 - 5.9e-09 36.1 2.2 4.2e-08 33.4 0.3 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KIY73017.1 - 2.8e-07 30.3 1.0 2.8e-07 30.3 1.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIY73017.1 - 5e-07 29.5 0.4 2.2e-06 27.4 0.4 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KIY73017.1 - 5.5e-06 26.0 0.5 0.00039 20.1 0.0 2.5 2 0 0 2 2 2 1 RING-like zinc finger zf-ANAPC11 PF12861.7 KIY73017.1 - 1.1e-05 25.3 0.2 0.00014 21.8 0.1 2.5 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 KIY73017.1 - 8.9e-05 22.4 1.1 0.00017 21.5 0.3 1.8 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KIY73017.1 - 0.00041 20.1 0.4 0.00041 20.1 0.4 1.6 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KIY73017.1 - 0.0014 18.6 6.7 0.029 14.4 2.5 3.1 2 1 1 3 3 3 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KIY73017.1 - 0.004 17.0 1.8 0.0073 16.2 0.5 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 KIY73017.1 - 0.015 15.6 1.1 0.028 14.7 1.1 1.4 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.6 KIY73017.1 - 0.02 14.7 0.6 0.045 13.6 0.1 1.7 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 KIY73017.1 - 0.033 14.3 1.9 0.058 13.6 0.6 2.0 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 KIY73017.1 - 0.056 13.3 0.1 0.18 11.7 0.1 1.8 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.8 KIY73017.1 - 0.087 13.0 3.3 0.83 9.9 3.3 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 KIY73017.1 - 0.28 10.8 6.0 0.046 13.4 1.7 1.7 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type RINGv PF12906.7 KIY73017.1 - 0.4 10.8 2.3 1.1 9.5 2.3 1.7 1 0 0 1 1 1 0 RING-variant domain Glyco_hydro_16 PF00722.21 KIY73018.1 - 1.3e-42 145.2 5.2 2e-42 144.7 5.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.19 KIY73018.1 - 0.0074 16.7 11.1 0.014 15.9 11.1 1.4 1 0 0 1 1 1 1 Chitin recognition protein DUF4064 PF13273.6 KIY73019.1 - 0.0047 17.2 0.1 0.021 15.1 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF4064) ELP6 PF09807.9 KIY73020.1 - 8.9e-17 61.3 0.3 1.6e-07 31.0 0.0 2.0 1 1 1 2 2 2 2 Elongation complex protein 6 Elong_Iki1 PF10483.9 KIY73020.1 - 3.1e-05 23.6 0.2 4.1e-05 23.2 0.2 1.1 1 0 0 1 1 1 1 Elongator subunit Iki1 Fungal_trans PF04082.18 KIY73021.1 - 3.2e-23 82.1 0.5 5.2e-23 81.4 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY73021.1 - 2.1e-08 34.1 9.3 4.1e-08 33.2 9.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BTB PF00651.31 KIY73022.1 - 1.5e-10 41.3 0.0 2.6e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Monellin PF09200.10 KIY73024.1 - 0.054 13.3 0.0 0.08 12.8 0.0 1.3 1 0 0 1 1 1 0 Monellin Med26 PF08711.11 KIY73024.1 - 0.11 12.5 0.3 0.22 11.6 0.3 1.5 1 1 0 1 1 1 0 TFIIS helical bundle-like domain PWWP PF00855.17 KIY73025.1 - 4.1e-18 65.6 0.0 6.8e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 PWWP domain ABC1 PF03109.16 KIY73026.1 - 8.7e-33 113.0 0.0 1.6e-32 112.2 0.0 1.4 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.22 KIY73026.1 - 8.9e-05 22.2 0.1 0.00037 20.1 0.0 1.9 2 0 0 2 2 2 1 RIO1 family GHMP_kinases_N PF00288.26 KIY73027.1 - 1e-12 48.1 0.9 2.2e-12 47.0 0.9 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KIY73027.1 - 2.7e-06 27.7 0.0 8.2e-06 26.1 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal DUF2935 PF11155.8 KIY73027.1 - 0.15 12.4 0.0 0.41 11.0 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF2935) Aa_trans PF01490.18 KIY73028.1 - 8.7e-77 258.5 28.2 1.1e-76 258.2 28.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KIY73028.1 - 4.4e-05 22.7 14.8 4.4e-05 22.7 14.8 2.6 1 1 2 3 3 3 1 Tryptophan/tyrosine permease family Polysacc_synt_C PF14667.6 KIY73028.1 - 0.00073 19.6 1.7 0.00073 19.6 1.7 4.0 2 1 3 5 5 5 1 Polysaccharide biosynthesis C-terminal domain DUF2574 PF10836.8 KIY73028.1 - 0.065 13.1 1.0 2.6 8.0 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2574) Fe_hyd_lg_C PF02906.14 KIY73029.1 - 2.3e-61 207.5 0.0 5.1e-61 206.4 0.0 1.6 2 0 0 2 2 2 1 Iron only hydrogenase large subunit, C-terminal domain Metallothio_Euk PF12749.7 KIY73030.1 - 0.98 9.6 9.0 1.8 8.8 9.0 1.5 1 1 0 1 1 1 0 Eukaryotic metallothionein zf-RING_10 PF16685.5 KIY73030.1 - 2.5 8.3 10.3 3.4 7.9 7.1 2.4 1 1 2 3 3 3 0 zinc RING finger of MSL2 SNARE PF05739.19 KIY73031.1 - 4.2e-15 55.5 1.1 9.6e-15 54.3 0.2 2.1 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 KIY73031.1 - 1.8e-06 27.8 2.1 1.8e-06 27.8 2.1 1.9 2 1 1 3 3 3 1 Syntaxin Syntaxin_2 PF14523.6 KIY73031.1 - 0.12 12.7 3.2 1.6 9.2 0.8 2.6 2 1 0 2 2 2 0 Syntaxin-like protein DUF4876 PF16215.5 KIY73031.1 - 0.2 11.7 0.9 0.59 10.1 0.1 2.2 2 1 0 3 3 3 0 Protein of unknown function (DUF4876) MCPsignal PF00015.21 KIY73031.1 - 0.35 10.6 4.5 0.49 10.2 0.5 2.4 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain MS_channel PF00924.18 KIY73032.1 - 2.1e-21 76.5 0.3 3.6e-21 75.7 0.3 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 KIY73032.1 - 0.0029 17.0 0.2 0.0065 15.9 0.2 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KIY73032.1 - 0.029 14.3 0.1 0.07 13.1 0.1 1.6 1 0 0 1 1 1 0 EF-hand domain EF-hand_7 PF13499.6 KIY73032.1 - 0.078 13.4 0.0 0.18 12.3 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair RNA_pol_A_bac PF01000.26 KIY73033.1 - 2.3e-27 95.6 0.0 3.9e-27 94.8 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 KIY73033.1 - 5.2e-20 70.7 0.0 7.9e-20 70.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L_2 PF13656.6 KIY73033.1 - 0.093 12.5 0.0 2 8.3 0.0 2.2 2 0 0 2 2 2 0 RNA polymerase Rpb3/Rpb11 dimerisation domain Peptidase_C14 PF00656.22 KIY73034.1 - 1.9e-63 214.7 0.1 2.4e-63 214.4 0.1 1.0 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.6 KIY73034.1 - 0.057 13.4 0.1 0.057 13.4 0.1 2.5 3 1 0 3 3 3 0 Raptor N-terminal CASPase like domain AMOP PF03782.17 KIY73034.1 - 0.54 10.4 4.7 1 9.4 0.4 2.2 2 0 0 2 2 2 0 AMOP domain SAPS PF04499.15 KIY73035.1 - 0.00041 19.3 1.7 0.0056 15.5 3.0 1.9 2 0 0 2 2 2 1 SIT4 phosphatase-associated protein NPR3 PF03666.13 KIY73035.1 - 7.8 5.2 9.6 0.88 8.3 4.1 1.9 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 ADH_zinc_N PF00107.26 KIY73036.1 - 4.8e-30 104.2 1.3 7.3e-30 103.6 1.3 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KIY73036.1 - 4.2e-11 44.0 0.0 6.7e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIY73036.1 - 1e-05 25.4 0.0 3.2e-05 23.8 0.0 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 KIY73036.1 - 0.053 13.0 1.8 0.088 12.2 1.8 1.3 1 0 0 1 1 1 0 short chain dehydrogenase ADH_zinc_N PF00107.26 KIY73037.1 - 9.8e-32 109.7 0.2 1.4e-31 109.2 0.2 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KIY73037.1 - 2e-13 51.6 0.0 3.1e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIY73037.1 - 2.9e-07 30.3 0.0 1.3e-06 28.2 0.0 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 KIY73037.1 - 0.018 14.5 0.2 0.028 13.9 0.2 1.3 1 0 0 1 1 1 0 short chain dehydrogenase AlaDh_PNT_C PF01262.21 KIY73037.1 - 0.036 13.4 0.2 0.059 12.7 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain adh_short PF00106.25 KIY73038.1 - 1.5e-17 63.7 0.0 2.4e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIY73038.1 - 1.2e-09 38.0 0.0 1.8e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIY73038.1 - 0.00094 19.1 0.0 0.0014 18.5 0.0 1.3 1 0 0 1 1 1 1 KR domain GatB_N PF02934.15 KIY73039.1 - 1.2e-106 356.2 0.0 1.5e-106 355.8 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 KIY73039.1 - 1.5e-32 112.5 0.0 3.2e-32 111.5 0.0 1.5 2 0 0 2 2 2 1 GatB domain PC4 PF02229.16 KIY73040.1 - 1.8e-23 81.9 0.1 3.2e-23 81.1 0.1 1.4 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) TFIIF_alpha PF05793.12 KIY73040.1 - 0.5 8.9 15.0 0.53 8.8 15.0 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF913 PF06025.12 KIY73041.1 - 2.2e-101 339.5 0.0 2.2e-101 339.5 0.0 5.9 6 1 0 6 6 6 2 Domain of Unknown Function (DUF913) HECT PF00632.25 KIY73041.1 - 5.2e-92 308.6 0.0 1.7e-91 306.9 0.0 2.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF908 PF06012.12 KIY73041.1 - 3.5e-88 296.4 5.1 3.5e-88 296.4 5.1 2.8 4 0 0 4 4 4 1 Domain of Unknown Function (DUF908) UBM PF14377.6 KIY73041.1 - 5.3e-30 101.9 13.7 3.6e-11 42.1 0.7 4.1 3 0 0 3 3 3 3 Ubiquitin binding region UBA PF00627.31 KIY73041.1 - 1.3e-11 44.2 0.1 3.8e-11 42.6 0.1 1.9 1 0 0 1 1 1 1 UBA/TS-N domain Yippee-Mis18 PF03226.14 KIY73042.1 - 8.7e-09 35.5 0.3 1.1e-08 35.2 0.3 1.2 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf_C2HC_14 PF18574.1 KIY73042.1 - 0.37 10.6 5.3 2 8.3 0.2 2.3 2 0 0 2 2 2 0 C2HC Zing finger domain zf-Sec23_Sec24 PF04810.15 KIY73042.1 - 0.83 9.7 4.8 2 8.5 0.2 2.6 2 1 0 2 2 2 0 Sec23/Sec24 zinc finger Amidohydro_1 PF01979.20 KIY73043.1 - 2e-33 116.2 0.0 2.3e-33 115.9 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KIY73043.1 - 3e-16 59.9 0.1 1.6e-07 31.2 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family zf-RING_2 PF13639.6 KIY73044.1 - 2.6e-12 46.8 6.8 4.4e-12 46.1 6.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KIY73044.1 - 1.4e-06 27.9 3.9 1.4e-06 27.9 3.9 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KIY73044.1 - 4.4e-06 26.4 5.8 7.4e-06 25.7 5.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KIY73044.1 - 8.8e-06 25.9 4.5 2e-05 24.8 4.5 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_4 PF14570.6 KIY73044.1 - 1e-05 25.2 4.6 1.8e-05 24.5 4.6 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 KIY73044.1 - 2.6e-05 24.2 2.5 4.5e-05 23.4 2.5 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 KIY73044.1 - 4.7e-05 23.3 2.7 8e-05 22.5 2.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KIY73044.1 - 0.00011 21.9 2.2 0.00018 21.3 2.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIY73044.1 - 0.00014 21.7 3.6 0.00024 20.9 3.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 KIY73044.1 - 0.0049 17.0 3.2 0.012 15.8 3.2 1.6 1 1 0 1 1 1 1 FANCL C-terminal domain Prok-RING_4 PF14447.6 KIY73044.1 - 0.007 16.2 8.1 0.11 12.4 8.8 2.2 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KIY73044.1 - 0.008 16.2 5.3 0.15 12.1 1.7 2.5 2 0 0 2 2 2 1 RING-type zinc-finger RINGv PF12906.7 KIY73044.1 - 0.029 14.5 3.3 0.052 13.7 3.3 1.4 1 0 0 1 1 1 0 RING-variant domain Prok-RING_1 PF14446.6 KIY73044.1 - 0.66 10.0 7.3 6.3 6.8 4.3 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PHD PF00628.29 KIY73044.1 - 0.96 9.4 4.2 1.8 8.5 3.8 1.7 1 1 0 1 1 1 0 PHD-finger EF-hand_1 PF00036.32 KIY73045.1 - 5e-19 66.4 0.5 0.00015 21.1 0.0 4.9 4 1 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 KIY73045.1 - 7.4e-19 66.0 0.0 6.2e-05 22.6 0.0 4.5 5 0 0 5 5 5 4 EF-hand domain EF-hand_7 PF13499.6 KIY73045.1 - 1.6e-17 63.7 0.0 1.6e-08 34.9 0.0 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KIY73045.1 - 6e-16 57.1 0.2 8.9e-05 21.8 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 KIY73045.1 - 3.4e-11 42.8 1.2 7.7e-07 28.9 0.0 4.3 3 2 1 4 4 4 2 EF-hand domain pair F-box-like PF12937.7 KIY73046.1 - 0.0066 16.3 0.0 0.017 15.0 0.0 1.8 1 0 0 1 1 1 1 F-box-like Ferrochelatase PF00762.19 KIY73047.1 - 1.3e-96 323.4 0.0 1.5e-96 323.2 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase CbiX PF01903.17 KIY73047.1 - 0.012 15.9 0.1 4 7.8 0.0 3.1 3 0 0 3 3 3 0 CbiX RabGAP-TBC PF00566.18 KIY73048.1 - 1.6e-54 184.8 1.1 2.1e-54 184.4 0.1 1.7 2 0 0 2 2 2 1 Rab-GTPase-TBC domain ZapB PF06005.12 KIY73048.1 - 0.006 17.0 3.8 0.69 10.4 0.0 2.5 2 0 0 2 2 2 1 Cell division protein ZapB DUF4686 PF15742.5 KIY73048.1 - 0.048 12.8 9.0 0.62 9.1 3.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4686) FlxA PF14282.6 KIY73048.1 - 0.056 13.4 2.5 0.56 10.2 0.1 2.3 2 0 0 2 2 2 0 FlxA-like protein Seryl_tRNA_N PF02403.22 KIY73048.1 - 0.058 13.6 0.6 0.058 13.6 0.6 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain CtIP_N PF10482.9 KIY73048.1 - 0.065 13.3 0.5 0.065 13.3 0.5 2.2 2 0 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain APG6_N PF17675.1 KIY73048.1 - 0.13 12.8 12.0 0.19 12.3 3.5 2.5 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF724 PF05266.14 KIY73048.1 - 0.23 11.3 4.0 0.82 9.5 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF724) ATG16 PF08614.11 KIY73048.1 - 0.62 10.3 15.8 0.9 9.7 6.0 2.3 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) STAT_alpha PF01017.20 KIY73048.1 - 0.65 9.9 5.6 1.8 8.4 1.0 2.2 2 0 0 2 2 2 0 STAT protein, all-alpha domain LMP PF04778.12 KIY73048.1 - 0.83 9.5 7.7 0.42 10.5 1.2 2.3 2 0 0 2 2 2 0 LMP repeated region TMF_DNA_bd PF12329.8 KIY73048.1 - 2.8 8.0 13.7 0.17 11.9 5.3 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.15 KIY73048.1 - 5 7.0 11.5 2.2 8.1 2.0 3.1 2 1 1 3 3 3 0 Septum formation initiator TPR_2 PF07719.17 KIY73049.1 - 1.3e-24 84.3 39.4 0.0013 18.7 0.4 14.6 14 0 0 14 14 13 6 Tetratricopeptide repeat TPR_19 PF14559.6 KIY73049.1 - 1.5e-23 83.0 46.2 3.3e-06 27.5 1.7 10.9 9 1 2 11 11 11 7 Tetratricopeptide repeat TPR_8 PF13181.6 KIY73049.1 - 7.9e-21 72.5 15.1 0.0025 17.9 0.1 11.6 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_1 PF00515.28 KIY73049.1 - 1.9e-20 71.7 15.8 0.00054 19.7 0.1 10.8 10 1 0 10 10 10 5 Tetratricopeptide repeat TPR_14 PF13428.6 KIY73049.1 - 1.5e-19 69.0 65.4 0.0018 18.9 0.6 16.9 11 4 7 18 18 18 6 Tetratricopeptide repeat TPR_16 PF13432.6 KIY73049.1 - 3.8e-19 69.0 56.0 7.3e-07 29.7 5.0 11.3 10 2 2 13 13 10 6 Tetratricopeptide repeat TPR_17 PF13431.6 KIY73049.1 - 6.6e-17 60.6 29.3 0.043 14.2 0.3 13.4 14 1 1 15 15 14 5 Tetratricopeptide repeat TPR_7 PF13176.6 KIY73049.1 - 5.2e-14 51.2 12.2 0.029 14.4 0.0 9.4 7 1 1 8 8 8 4 Tetratricopeptide repeat TPR_11 PF13414.6 KIY73049.1 - 1.1e-13 50.6 24.3 0.0036 17.0 0.1 10.5 8 2 3 11 11 10 4 TPR repeat TPR_6 PF13174.6 KIY73049.1 - 1.3e-11 44.3 22.5 0.29 11.8 0.1 11.4 11 0 0 11 11 9 4 Tetratricopeptide repeat TPR_12 PF13424.6 KIY73049.1 - 1.7e-11 44.2 41.4 0.00097 19.4 0.1 11.6 10 5 4 15 15 13 5 Tetratricopeptide repeat ANAPC3 PF12895.7 KIY73049.1 - 8.4e-09 35.5 14.1 0.0014 18.8 0.0 7.0 7 1 1 8 8 8 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 KIY73049.1 - 6.7e-07 29.4 32.6 0.0011 19.0 0.1 8.1 7 1 2 9 9 9 4 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 KIY73049.1 - 0.00097 18.8 7.4 0.085 12.5 0.1 4.5 5 0 0 5 5 4 2 Bacterial type III secretion protein (HrpB1_HrpK) Fis1_TPR_C PF14853.6 KIY73049.1 - 0.0056 16.7 0.4 10 6.3 0.0 5.3 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_20 PF14561.6 KIY73049.1 - 0.0075 16.6 28.4 0.24 11.7 0.6 7.7 7 2 1 8 8 7 3 Tetratricopeptide repeat RPN7 PF10602.9 KIY73049.1 - 0.0081 15.9 3.7 5.3 6.7 0.2 4.9 5 0 0 5 5 5 1 26S proteasome subunit RPN7 BTAD PF03704.17 KIY73049.1 - 0.014 15.8 0.2 0.014 15.8 0.2 6.9 8 1 0 8 8 8 0 Bacterial transcriptional activator domain NARP1 PF12569.8 KIY73049.1 - 0.032 13.1 4.1 0.26 10.1 0.1 3.6 4 0 0 4 4 4 0 NMDA receptor-regulated protein 1 TPR_10 PF13374.6 KIY73049.1 - 0.041 13.8 25.3 1.7 8.6 0.1 7.8 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_22 PF18833.1 KIY73049.1 - 0.081 13.1 0.1 0.34 11.1 0.0 2.1 2 0 0 2 2 1 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 KIY73049.1 - 0.21 12.1 10.9 0.35 11.3 0.1 5.1 5 2 0 5 5 5 0 Alkyl sulfatase dimerisation FAT PF02259.23 KIY73049.1 - 0.27 10.4 3.6 15 4.7 0.0 4.1 5 0 0 5 5 5 0 FAT domain DUF2225 PF09986.9 KIY73049.1 - 0.3 10.8 0.8 3.9 7.1 0.0 3.2 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) Acyltransferase PF01553.21 KIY73050.1 - 1.2e-10 41.1 0.0 6e-05 22.7 0.0 2.3 2 0 0 2 2 2 2 Acyltransferase RIO1 PF01163.22 KIY73052.1 - 0.049 13.2 0.1 2.5 7.6 0.0 2.1 1 1 1 2 2 2 0 RIO1 family DASH_Duo1 PF08651.10 KIY73053.1 - 4.1e-18 64.9 0.2 6.3e-18 64.3 0.2 1.3 1 0 0 1 1 1 1 DASH complex subunit Duo1 GPI-anchored PF10342.9 KIY73054.1 - 2.4e-07 31.4 0.3 3.2e-07 31.0 0.3 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family S8_pro-domain PF16470.5 KIY73055.1 - 0.008 16.9 0.0 0.0093 16.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase S8 pro-domain DUF21 PF01595.20 KIY73056.1 - 4.1e-29 101.5 0.1 7.5e-29 100.7 0.1 1.4 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 KIY73056.1 - 0.00064 20.1 0.3 1.2 9.6 0.0 3.0 3 1 0 3 3 3 2 CBS domain MCM PF00493.23 KIY73057.1 - 2.5e-105 350.5 0.0 5.7e-105 349.4 0.0 1.6 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KIY73057.1 - 1.3e-30 105.9 0.1 2.2e-30 105.1 0.1 1.3 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KIY73057.1 - 3.3e-21 75.5 1.5 1e-20 73.9 1.5 1.9 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KIY73057.1 - 1.1e-20 74.1 0.9 1.1e-20 74.1 0.9 2.2 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 KIY73057.1 - 2.6e-08 33.5 0.1 8.6e-06 25.3 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KIY73057.1 - 6.7e-06 26.2 0.0 3e-05 24.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase_C PF13335.6 KIY73057.1 - 0.00093 19.8 1.7 0.0018 18.9 0.7 2.0 2 0 0 2 2 1 1 Magnesium chelatase, subunit ChlI C-terminal AAA_lid_2 PF17863.1 KIY73057.1 - 0.02 14.8 0.1 0.059 13.2 0.1 1.8 1 0 0 1 1 1 0 AAA lid domain AAA_lid_5 PF17865.1 KIY73057.1 - 0.027 14.6 0.0 0.11 12.6 0.0 2.0 2 0 0 2 2 2 0 Midasin AAA lid domain AAA_3 PF07726.11 KIY73057.1 - 0.027 14.3 0.0 0.08 12.8 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NolX PF05819.11 KIY73057.1 - 0.048 13.0 0.0 0.086 12.2 0.0 1.3 1 0 0 1 1 1 0 NolX protein Sigma54_activat PF00158.26 KIY73057.1 - 0.13 11.9 0.0 0.65 9.7 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain Cauli_VI PF01693.16 KIY73058.1 - 4.7e-09 36.4 0.2 9e-09 35.5 0.2 1.5 1 0 0 1 1 1 1 Caulimovirus viroplasmin ATG27 PF09451.10 KIY73059.1 - 7.1e-73 245.7 0.0 8.3e-73 245.5 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 Man-6-P_recep PF02157.15 KIY73059.1 - 0.00028 20.1 0.0 0.00042 19.5 0.0 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate receptor DUF2207 PF09972.9 KIY73059.1 - 0.18 10.6 0.0 0.24 10.1 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) MFS_1 PF07690.16 KIY73060.1 - 3.7e-34 118.2 32.1 3.7e-34 118.2 32.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Alpha-amylase PF00128.24 KIY73061.1 - 1.8e-17 64.0 0.0 1.2e-15 57.9 0.0 2.1 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.18 KIY73061.1 - 2.5e-12 47.1 0.0 7.3e-12 45.6 0.0 1.8 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain TSGP1 PF07771.11 KIY73061.1 - 0.14 12.3 0.1 0.27 11.4 0.1 1.4 1 0 0 1 1 1 0 Tick salivary peptide group 1 Peptidase_C14 PF00656.22 KIY73062.1 - 9.2e-55 186.3 0.0 1.1e-54 186.0 0.0 1.0 1 0 0 1 1 1 1 Caspase domain DEAD PF00270.29 KIY73063.1 - 1.4e-39 135.7 0.0 4.6e-39 134.0 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIY73063.1 - 5.4e-24 84.7 0.1 3.4e-23 82.1 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 KIY73063.1 - 2.7e-20 72.4 4.7 1.2e-19 70.3 4.7 2.2 1 0 0 1 1 1 1 DBP10CT (NUC160) domain Fungal_trans PF04082.18 KIY73065.1 - 2.9e-16 59.3 0.0 4.7e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY73065.1 - 0.0002 21.4 13.9 0.0002 21.4 13.9 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TGT PF01702.18 KIY73066.1 - 3.8e-131 437.4 0.0 4.5e-131 437.2 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase EMP70 PF02990.16 KIY73067.1 - 1.2e-193 644.6 0.8 1.2e-193 644.6 0.8 1.3 2 0 0 2 2 2 1 Endomembrane protein 70 SIC PF03482.13 KIY73068.1 - 0.067 13.4 0.1 0.17 12.1 0.1 1.7 1 0 0 1 1 1 0 sic protein repeat Ribosom_S12_S23 PF00164.25 KIY73069.1 - 2.3e-49 165.8 1.1 2.9e-49 165.4 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Transglut_core PF01841.19 KIY73070.1 - 9.9e-11 42.1 0.0 1.7e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily tRNA-synt_1b PF00579.25 KIY73071.1 - 2.3e-75 253.7 0.0 2.9e-75 253.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) TyrRSs_C PF16714.5 KIY73071.1 - 0.097 12.5 0.3 2.2 8.1 0.3 2.3 1 1 0 1 1 1 0 Tyrosyl-tRNA synthetase C-terminal domain DUF3629 PF12302.8 KIY73071.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3629) NAD_binding_4 PF07993.12 KIY73072.1 - 1.3e-27 96.7 0.0 2e-27 96.0 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 KIY73072.1 - 3.5e-12 46.3 0.0 5.7e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KIY73072.1 - 0.0082 15.6 0.0 0.43 9.9 0.0 2.1 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KIY73072.1 - 0.025 13.7 0.1 1.6 7.8 0.0 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain Lon_C PF05362.13 KIY73073.1 - 7e-68 228.2 0.2 1.3e-67 227.3 0.2 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 KIY73073.1 - 8.7e-36 123.7 0.1 1.8e-35 122.7 0.1 1.6 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 KIY73073.1 - 1.2e-22 80.7 0.0 4.1e-22 79.0 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KIY73073.1 - 2.5e-07 30.8 0.0 5.1e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KIY73073.1 - 1.3e-05 25.4 0.0 5.6e-05 23.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_PrkA PF08298.11 KIY73073.1 - 2.3e-05 23.5 0.0 4.3e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 PrkA AAA domain ChlI PF13541.6 KIY73073.1 - 2.3e-05 24.2 0.0 5.2e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.6 KIY73073.1 - 0.00013 22.4 0.1 0.0007 20.0 0.0 2.3 2 0 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.6 KIY73073.1 - 0.00038 20.7 0.1 0.0049 17.1 0.1 2.5 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KIY73073.1 - 0.00042 20.1 0.0 0.0018 18.1 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KIY73073.1 - 0.00055 20.5 0.2 0.0026 18.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 KIY73073.1 - 0.0062 16.6 0.0 0.018 15.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KIY73073.1 - 0.014 15.8 0.0 0.063 13.7 0.0 2.1 2 0 0 2 2 2 0 RNA helicase IstB_IS21 PF01695.17 KIY73073.1 - 0.025 14.3 0.0 0.052 13.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein SKI PF01202.22 KIY73073.1 - 0.039 14.1 0.0 0.11 12.7 0.0 1.8 1 0 0 1 1 1 0 Shikimate kinase AAA_30 PF13604.6 KIY73073.1 - 0.043 13.5 0.0 0.098 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 KIY73073.1 - 0.052 13.4 0.0 0.17 11.7 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 KIY73073.1 - 0.072 13.0 0.0 0.2 11.6 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase ABC_tran PF00005.27 KIY73073.1 - 0.1 13.1 0.6 0.34 11.4 0.1 2.1 2 0 0 2 2 2 0 ABC transporter MCM PF00493.23 KIY73073.1 - 0.1 11.7 0.0 0.22 10.6 0.0 1.5 1 0 0 1 1 1 0 MCM P-loop domain NTPase_1 PF03266.15 KIY73073.1 - 0.11 12.4 0.2 0.49 10.3 0.1 2.1 1 1 1 2 2 2 0 NTPase AAA_24 PF13479.6 KIY73073.1 - 0.15 11.8 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KIY73073.1 - 0.16 12.0 0.0 0.36 10.8 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TIP49 PF06068.13 KIY73073.1 - 0.17 11.1 1.5 0.27 10.4 0.1 2.0 3 0 0 3 3 3 0 TIP49 P-loop domain AAA_7 PF12775.7 KIY73073.1 - 0.24 10.9 0.3 0.53 9.8 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_23 PF13476.6 KIY73073.1 - 0.49 10.9 3.0 4.4 7.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain PBP1_TM PF14812.6 KIY73074.1 - 0.16 12.3 3.3 0.36 11.2 3.3 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal IPK PF03770.16 KIY73075.1 - 1.3e-42 145.9 0.0 1.6e-42 145.6 0.0 1.1 1 0 0 1 1 1 1 Inositol polyphosphate kinase MFS_1 PF07690.16 KIY73076.1 - 5.5e-49 167.0 34.9 2e-45 155.3 21.9 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIY73076.1 - 3.5e-10 39.3 9.4 3.5e-10 39.3 9.4 2.9 3 0 0 3 3 3 2 Sugar (and other) transporter MFS_3 PF05977.13 KIY73076.1 - 1.3e-05 23.8 5.5 1.3e-05 23.8 5.5 2.4 2 1 0 2 2 2 1 Transmembrane secretion effector TRI12 PF06609.13 KIY73076.1 - 0.00092 17.7 6.9 0.0019 16.7 6.9 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 KIY73076.1 - 0.0033 16.8 5.1 0.0033 16.8 5.1 3.3 2 2 1 3 3 3 1 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 KIY73076.1 - 0.016 14.1 0.3 0.016 14.1 0.3 3.1 2 1 1 4 4 4 0 MFS_1 like family MFS_2 PF13347.6 KIY73076.1 - 0.062 11.8 20.9 0.26 9.8 11.6 3.3 3 1 0 3 3 3 0 MFS/sugar transport protein Pox_MCEL PF03291.16 KIY73076.1 - 0.27 10.3 0.0 0.39 9.8 0.0 1.1 1 0 0 1 1 1 0 mRNA capping enzyme OATP PF03137.20 KIY73076.1 - 3.2 5.9 13.1 0.56 8.4 2.5 2.6 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Lipase_GDSL PF00657.22 KIY73077.1 - 5.6e-17 62.4 0.1 7e-17 62.1 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 KIY73077.1 - 3.3e-15 56.9 0.5 4.6e-15 56.5 0.5 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL_3 PF14606.6 KIY73077.1 - 0.00011 22.4 0.0 0.00015 21.9 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family CTP_transf_1 PF01148.20 KIY73078.1 - 6.6e-71 239.2 18.9 1.1e-70 238.5 18.9 1.3 1 0 0 1 1 1 1 Cytidylyltransferase family MASE2 PF05230.11 KIY73078.1 - 0.029 14.4 1.9 0.13 12.3 0.1 2.7 2 0 0 2 2 2 0 MASE2 domain F-box-like PF12937.7 KIY73079.1 - 2.5e-07 30.5 1.0 8.8e-07 28.7 1.0 2.0 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.6 KIY73079.1 - 0.13 12.2 0.8 0.96 9.4 0.8 2.4 2 1 0 2 2 2 0 F-box-like domain SRAP PF02586.14 KIY73080.1 - 5.6e-64 215.7 0.1 8.8e-64 215.0 0.1 1.3 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) Topoisom_I PF01028.20 KIY73081.1 - 1.4e-98 328.8 4.3 1.4e-98 328.8 4.3 2.0 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 KIY73081.1 - 3.1e-95 317.7 0.6 3.1e-95 317.7 0.6 4.3 4 2 1 5 5 5 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 KIY73081.1 - 7.1e-32 109.2 2.2 7.1e-32 109.2 2.2 2.4 2 0 0 2 2 2 1 C-terminal topoisomerase domain Zip PF02535.22 KIY73081.1 - 0.85 8.8 5.4 1.9 7.6 5.4 1.6 1 0 0 1 1 1 0 ZIP Zinc transporter NDUF_B12 PF08122.12 KIY73082.1 - 1.2e-19 70.1 0.8 1.3e-19 70.0 0.8 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family Hemerythrin PF01814.23 KIY73083.1 - 1.9e-13 51.2 5.1 2.2e-13 50.9 5.1 1.1 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain SCAN PF02023.17 KIY73083.1 - 0.089 12.6 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 SCAN domain Pkinase_Tyr PF07714.17 KIY73084.1 - 7.1e-15 55.0 0.0 1.4e-14 54.0 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 KIY73084.1 - 1.1e-07 31.5 0.0 1.8e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain COG2 PF06148.11 KIY73086.1 - 3.6e-27 95.1 3.5 1.9e-26 92.8 1.3 2.9 3 0 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF3510 PF12022.8 KIY73086.1 - 1e-26 93.8 0.0 2.4e-26 92.6 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3510) Vps51 PF08700.11 KIY73086.1 - 0.0029 17.6 0.2 0.011 15.8 0.2 2.0 1 0 0 1 1 1 1 Vps51/Vps67 Vps54_N PF10475.9 KIY73086.1 - 0.023 14.0 0.6 0.023 14.0 0.6 2.6 3 0 0 3 3 3 0 Vacuolar-sorting protein 54, of GARP complex Spc7 PF08317.11 KIY73086.1 - 0.086 11.7 7.2 0.18 10.7 2.4 2.4 2 0 0 2 2 2 0 Spc7 kinetochore protein Zw10 PF06248.13 KIY73086.1 - 0.22 10.1 2.9 0.37 9.3 1.2 1.8 1 1 0 2 2 2 0 Centromere/kinetochore Zw10 COG5 PF10392.9 KIY73086.1 - 1.2 9.4 8.9 4 7.6 2.8 3.7 3 1 1 4 4 4 0 Golgi transport complex subunit 5 Baculo_PEP_C PF04513.12 KIY73086.1 - 3.4 7.7 5.8 18 5.3 1.2 3.3 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Na_Ca_ex PF01699.24 KIY73087.1 - 1.3e-34 119.4 33.9 4.9e-19 68.8 13.3 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF1129 PF06570.11 KIY73087.1 - 0.13 11.8 3.4 0.3 10.5 3.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) Otopetrin PF03189.13 KIY73087.1 - 1.3 7.8 4.5 2.8 6.7 4.5 1.5 1 0 0 1 1 1 0 Otopetrin CYSTM PF12734.7 KIY73088.1 - 1.3e-10 41.4 11.2 1.3e-10 41.4 11.2 2.8 1 1 1 2 2 2 1 Cysteine-rich TM module stress tolerance PALP PF00291.25 KIY73089.1 - 2.9e-76 256.7 0.2 4.3e-76 256.1 0.2 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 KIY73089.1 - 1.1e-39 134.1 0.1 8.5e-23 79.9 0.0 2.6 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase NOA36 PF06524.12 KIY73090.1 - 0.046 13.0 7.2 0.091 12.1 7.2 1.4 1 0 0 1 1 1 0 NOA36 protein NIF3 PF01784.18 KIY73091.1 - 1.5e-67 227.8 0.0 1.8e-67 227.5 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) Peptidase_C14 PF00656.22 KIY73092.1 - 1.6e-38 133.1 0.0 7.6e-38 130.9 0.0 1.8 1 1 0 1 1 1 1 Caspase domain BAT PF15915.5 KIY73092.1 - 0.078 12.9 0.1 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 GAF and HTH_10 associated domain Vps8 PF12816.7 KIY73093.1 - 2.1e-45 154.7 0.0 4.7e-45 153.6 0.0 1.6 1 0 0 1 1 1 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.20 KIY73093.1 - 0.0039 17.1 0.0 0.0097 15.8 0.0 1.6 1 0 0 1 1 1 1 Region in Clathrin and VPS MA3 PF02847.17 KIY73096.1 - 6.9e-26 90.4 0.4 1.4e-25 89.4 0.4 1.6 1 0 0 1 1 1 1 MA3 domain Cnd1 PF12717.7 KIY73096.1 - 0.029 14.4 0.9 0.99 9.4 0.1 2.3 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 AF-4 PF05110.13 KIY73096.1 - 5.1 5.0 26.3 0.0089 14.2 15.8 1.6 2 0 0 2 2 2 0 AF-4 proto-oncoprotein D123 PF07065.14 KIY73096.1 - 8.2 5.5 6.5 2.9 7.0 0.7 2.3 2 0 0 2 2 2 0 D123 CCDC106 PF15794.5 KIY73096.1 - 9.6 5.8 10.4 0.64 9.7 4.1 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 BAR_2 PF10455.9 KIY73097.1 - 3.5e-46 157.6 0.0 5.2e-46 157.1 0.0 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 KIY73097.1 - 6e-16 58.8 1.1 1.5e-15 57.5 1.1 1.6 1 1 0 1 1 1 1 BAR domain DUF4642 PF15484.6 KIY73097.1 - 0.16 12.2 1.9 0.18 12.0 0.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4642) TipAS PF07739.13 KIY73097.1 - 0.21 12.1 2.7 12 6.5 0.0 2.8 2 1 1 3 3 3 0 TipAS antibiotic-recognition domain Phasin_2 PF09361.10 KIY73097.1 - 0.37 11.1 9.9 0.66 10.3 7.4 2.7 2 1 1 3 3 3 0 Phasin protein Exonuc_VII_L PF02601.15 KIY73097.1 - 0.42 10.1 7.6 0.59 9.6 6.4 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit CtaG_Cox11 PF04442.14 KIY73098.1 - 9.9e-61 204.2 0.0 1.2e-60 203.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 PHD PF00628.29 KIY73101.1 - 3.6e-11 42.8 9.0 6.5e-11 42.0 9.0 1.4 1 0 0 1 1 1 1 PHD-finger zf-CW PF07496.15 KIY73101.1 - 0.0031 17.5 1.7 0.0074 16.3 1.7 1.7 1 0 0 1 1 1 1 CW-type Zinc Finger PHD_2 PF13831.6 KIY73101.1 - 0.31 10.6 5.3 0.59 9.7 5.3 1.4 1 0 0 1 1 1 0 PHD-finger Lactamase_B PF00753.27 KIY73102.1 - 4.8e-18 65.9 2.6 6.9e-18 65.4 2.6 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily BLACT_WH PF17778.1 KIY73102.1 - 1.1e-14 54.1 0.3 2.7e-14 52.9 0.1 1.8 2 0 0 2 2 2 1 Beta-lactamase associated winged helix domain Lactamase_B_2 PF12706.7 KIY73102.1 - 0.0013 18.3 2.4 0.0033 16.9 2.4 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Aldo_ket_red PF00248.21 KIY73103.1 - 2e-76 257.0 0.0 2.3e-76 256.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HTH_23 PF13384.6 KIY73103.1 - 0.11 12.4 0.1 0.88 9.5 0.0 2.5 3 0 0 3 3 3 0 Homeodomain-like domain DUF1118 PF06549.12 KIY73103.1 - 0.19 12.0 0.1 31 4.9 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1118) SNF2_N PF00176.23 KIY73104.1 - 3.5e-56 190.4 0.1 6e-56 189.7 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KIY73104.1 - 6.5e-20 71.5 0.0 1.5e-18 67.2 0.1 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIY73104.1 - 1.4e-06 28.5 0.0 7.4e-06 26.1 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KIY73104.1 - 8.6e-06 25.1 0.3 1.6e-05 24.2 0.3 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase HHH_3 PF12836.7 KIY73104.1 - 0.037 14.3 0.1 0.13 12.5 0.0 1.9 2 0 0 2 2 2 0 Helix-hairpin-helix motif DUF244 PF03112.14 KIY73104.1 - 0.24 11.3 1.3 0.45 10.3 0.4 1.9 2 1 0 2 2 2 0 Uncharacterized protein family (ORF7) DUF Mito_carr PF00153.27 KIY73105.1 - 1.1e-15 57.3 0.0 1.6e-07 31.1 0.0 2.5 2 0 0 2 2 2 2 Mitochondrial carrier protein Zn_clus PF00172.18 KIY73106.1 - 8.2e-06 25.8 6.5 8.2e-06 25.8 6.5 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SNF2_N PF00176.23 KIY73107.1 - 1.9e-62 211.0 0.0 2.3e-61 207.4 0.0 2.1 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KIY73107.1 - 1.8e-18 66.9 0.0 4.9e-18 65.5 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIY73107.1 - 5.4e-10 39.5 0.0 5e-08 33.1 0.0 3.4 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KIY73107.1 - 0.0011 18.2 0.0 0.0034 16.6 0.0 1.8 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 SWI2_SNF2 PF18766.1 KIY73107.1 - 0.035 13.8 0.0 0.18 11.4 0.0 2.0 2 0 0 2 2 2 0 SWI2/SNF2 ATPase zf-CCCH PF00642.24 KIY73108.1 - 3.3e-14 52.4 16.3 4.6e-07 29.6 3.0 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 KIY73108.1 - 0.00062 19.5 0.0 0.0035 17.1 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Torus PF16131.5 KIY73108.1 - 0.0024 18.6 1.1 1.6 9.5 0.1 2.3 2 0 0 2 2 2 2 Torus domain zf_CCCH_4 PF18345.1 KIY73108.1 - 0.0064 16.5 3.3 0.0064 16.5 3.3 2.5 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_3 PF15663.5 KIY73108.1 - 0.045 14.0 5.9 0.27 11.4 0.5 2.2 2 0 0 2 2 2 0 Zinc-finger containing family Alg14 PF08660.11 KIY73109.1 - 4.8e-58 196.0 0.0 6.2e-58 195.6 0.0 1.1 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like TPR_1 PF00515.28 KIY73110.1 - 1.9e-24 84.4 8.8 2.6e-06 27.0 0.1 6.2 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 KIY73110.1 - 1.5e-21 74.7 12.4 0.00022 21.2 0.1 7.5 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.17 KIY73110.1 - 8.6e-17 59.8 23.4 5e-05 23.1 0.3 8.5 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_11 PF13414.6 KIY73110.1 - 2.5e-12 46.3 7.6 1.6e-07 30.9 0.1 5.5 3 2 2 5 5 5 2 TPR repeat TPR_12 PF13424.6 KIY73110.1 - 1.2e-11 44.7 19.4 0.0018 18.6 0.2 5.9 4 1 2 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 KIY73110.1 - 1.4e-11 44.1 20.8 0.0014 19.2 0.3 7.4 4 2 4 8 8 7 5 Tetratricopeptide repeat ANAPC8 PF04049.13 KIY73110.1 - 2.2e-11 44.0 0.0 4.8e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_7 PF13176.6 KIY73110.1 - 5.3e-11 41.7 8.3 0.00012 21.8 0.0 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 KIY73110.1 - 9.3e-10 38.2 7.1 0.0077 16.5 0.1 6.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 KIY73110.1 - 1.6e-09 38.3 6.2 3.1e-08 34.1 1.7 6.2 5 2 1 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 KIY73110.1 - 5e-08 33.3 7.1 0.0021 18.6 0.2 5.1 1 1 4 5 5 5 2 Tetratricopeptide repeat TPR_15 PF13429.6 KIY73110.1 - 2.2e-07 30.4 5.2 0.0041 16.4 0.0 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 KIY73110.1 - 5.8e-07 29.6 5.7 0.0012 19.0 3.5 3.8 2 1 1 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KIY73110.1 - 0.00088 19.5 9.5 0.01 16.0 3.8 3.8 2 1 2 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 ChAPs PF09295.10 KIY73110.1 - 0.0042 16.1 0.0 0.75 8.7 0.0 2.7 1 1 2 3 3 3 3 ChAPs (Chs5p-Arf1p-binding proteins) DUF3856 PF12968.7 KIY73110.1 - 0.031 14.3 2.3 0.14 12.2 0.4 2.7 2 1 1 3 3 3 0 Domain of Unknown Function (DUF3856) TPR_6 PF13174.6 KIY73110.1 - 0.059 14.0 22.7 0.82 10.4 0.1 7.1 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_10 PF13374.6 KIY73110.1 - 4.1 7.4 15.5 3.4 7.7 0.1 4.8 6 0 0 6 6 4 0 Tetratricopeptide repeat GLTSCR1 PF15249.6 KIY73111.1 - 3.7e-26 91.5 2.4 5.3e-26 91.0 0.8 2.0 2 0 0 2 2 2 1 Conserved region of unknown function on GLTSCR protein DDE_Tnp_1_2 PF13586.6 KIY73111.1 - 0.19 12.1 2.3 3 8.3 0.0 3.0 2 1 0 2 2 2 0 Transposase DDE domain Voltage_CLC PF00654.20 KIY73112.1 - 3.1e-94 316.1 18.7 3.1e-94 316.1 18.7 2.0 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 KIY73112.1 - 0.00021 21.7 0.0 0.14 12.6 0.0 2.7 2 0 0 2 2 2 2 CBS domain AMP-binding PF00501.28 KIY73113.1 - 6.9e-79 265.4 0.0 8.8e-79 265.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ABC_tran PF00005.27 KIY73114.1 - 3.5e-41 140.9 0.0 4.7e-25 88.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KIY73114.1 - 1.8e-31 109.8 31.7 5.7e-20 72.1 12.7 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 KIY73114.1 - 0.00049 19.6 1.9 0.96 8.8 0.3 3.6 2 2 0 4 4 4 1 RecF/RecN/SMC N terminal domain FtsK_SpoIIIE PF01580.18 KIY73114.1 - 0.0012 18.3 0.4 1.6 8.1 0.2 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_22 PF13401.6 KIY73114.1 - 0.0059 16.9 3.4 2.5 8.4 0.0 3.4 3 1 0 3 3 2 1 AAA domain SbcCD_C PF13558.6 KIY73114.1 - 0.0074 16.5 1.5 4.2 7.7 0.0 3.2 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 KIY73114.1 - 0.034 13.9 1.9 6.5 6.6 0.5 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain T2SSE PF00437.20 KIY73114.1 - 0.042 12.9 0.6 1 8.4 0.1 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein DEAD PF00270.29 KIY73114.1 - 0.066 13.0 2.0 0.23 11.2 1.2 2.2 2 1 0 2 2 2 0 DEAD/DEAH box helicase AAA_16 PF13191.6 KIY73114.1 - 0.073 13.4 0.0 10 6.5 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain Adeno_IVa2 PF02456.15 KIY73114.1 - 0.1 11.4 0.1 0.23 10.2 0.0 1.5 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_7 PF12775.7 KIY73114.1 - 0.11 12.1 0.3 17 4.9 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region MWFE PF15879.5 KIY73114.1 - 0.13 12.4 0.6 1.7 8.8 0.2 2.7 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase MWFE subunit AAA_21 PF13304.6 KIY73114.1 - 0.15 11.8 2.6 0.33 10.7 0.1 2.5 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 KIY73114.1 - 0.19 11.8 1.4 14 5.8 0.1 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_23 PF13476.6 KIY73114.1 - 0.22 12.0 0.4 35 4.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 KIY73114.1 - 0.25 11.4 0.6 0.49 10.4 0.6 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain Yippee-Mis18 PF03226.14 KIY73115.1 - 9.5e-15 54.7 0.0 1.2e-14 54.4 0.0 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly NTP_transf_9 PF04248.12 KIY73117.1 - 9.9e-30 102.3 0.0 2.9e-26 91.2 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF427) Yip1 PF04893.17 KIY73118.1 - 3.1e-07 30.3 9.2 5.1e-07 29.6 9.2 1.4 1 0 0 1 1 1 1 Yip1 domain Ribosomal_S8e PF01201.22 KIY73119.1 - 7.4e-49 165.4 2.5 2.2e-48 163.9 2.5 1.8 1 1 0 1 1 1 1 Ribosomal protein S8e Cdc13_OB4_dimer PF18233.1 KIY73119.1 - 0.087 13.0 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 Cdc13 OB4 dimerization domain WW PF00397.26 KIY73120.1 - 0.0024 17.9 0.6 0.0055 16.8 0.6 1.7 1 0 0 1 1 1 1 WW domain NHL PF01436.21 KIY73120.1 - 0.11 12.5 0.2 0.28 11.3 0.2 1.7 1 0 0 1 1 1 0 NHL repeat F-box-like PF12937.7 KIY73122.1 - 0.0015 18.4 1.2 0.023 14.6 0.2 2.4 2 0 0 2 2 2 1 F-box-like Ipi1_N PF12333.8 KIY73122.1 - 0.17 12.5 0.6 3 8.5 0.0 2.8 2 1 1 3 3 3 0 Rix1 complex component involved in 60S ribosome maturation DUF1168 PF06658.12 KIY73123.1 - 1.1e-37 128.9 12.8 1.5e-37 128.4 12.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) DUF966 PF06136.13 KIY73123.1 - 0.056 13.2 6.7 0.069 12.9 6.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) LCD1 PF09798.9 KIY73123.1 - 0.082 11.4 3.5 0.096 11.2 3.5 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein CENP-N PF05238.13 KIY73123.1 - 0.16 11.3 5.4 0.18 11.1 5.4 1.0 1 0 0 1 1 1 0 Kinetochore protein CHL4 like DUF4692 PF15763.5 KIY73123.1 - 0.78 10.2 4.1 0.48 10.9 1.5 1.8 2 0 0 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) CDC45 PF02724.14 KIY73123.1 - 0.99 7.6 8.0 1.2 7.3 8.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 KIY73123.1 - 6 5.5 5.5 7 5.3 5.5 1.1 1 0 0 1 1 1 0 Presenilin RseC_MucC PF04246.12 KIY73125.1 - 0.19 11.7 2.5 0.52 10.3 1.0 2.1 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Pec_lyase_C PF00544.19 KIY73126.1 - 6.8e-35 120.6 5.7 9.3e-35 120.1 5.7 1.2 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 KIY73126.1 - 1.9e-05 24.5 7.3 0.0014 18.5 4.7 2.5 1 1 1 2 2 2 2 Right handed beta helix region NosD PF05048.13 KIY73126.1 - 0.0022 17.3 2.3 0.0039 16.5 2.0 1.4 1 1 0 1 1 1 1 Periplasmic copper-binding protein (NosD) NurA PF09376.10 KIY73126.1 - 0.054 13.2 0.0 0.07 12.8 0.0 1.2 1 0 0 1 1 1 0 NurA domain Sybindin PF04099.12 KIY73127.1 - 4e-22 78.7 0.0 5.6e-22 78.2 0.0 1.2 1 0 0 1 1 1 1 Sybindin-like family DUF846 PF05832.12 KIY73128.1 - 2.4e-46 157.2 7.3 2.9e-46 157.0 7.3 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) BPD_transp_1 PF00528.22 KIY73128.1 - 0.035 13.8 9.9 0.62 9.8 2.8 2.3 2 0 0 2 2 2 0 Binding-protein-dependent transport system inner membrane component UbiA PF01040.18 KIY73128.1 - 0.047 13.0 11.1 0.44 9.8 1.2 2.1 2 0 0 2 2 2 0 UbiA prenyltransferase family HR_lesion PF05514.11 KIY73128.1 - 0.055 13.7 0.1 0.07 13.3 0.1 1.3 1 0 0 1 1 1 0 HR-like lesion-inducing DUF3270 PF11674.8 KIY73128.1 - 0.13 12.5 0.0 0.13 12.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3270) TMCO5 PF14992.6 KIY73128.1 - 0.35 10.4 1.3 2.9 7.4 0.6 1.9 2 0 0 2 2 2 0 TMCO5 family Asn_synthase PF00733.21 KIY73129.1 - 1.4e-14 54.5 0.2 0.00022 21.0 0.0 3.1 2 1 1 3 3 3 3 Asparagine synthase GATase_7 PF13537.6 KIY73129.1 - 2.7e-05 24.1 0.0 7.7e-05 22.6 0.0 1.7 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KIY73129.1 - 0.011 15.9 0.0 0.029 14.6 0.0 1.7 1 1 0 1 1 1 0 Glutamine amidotransferase domain Fe-ADH PF00465.19 KIY73131.1 - 2.5e-67 227.2 0.0 3.1e-67 226.9 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 KIY73131.1 - 1.8e-14 54.0 0.0 2.5e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Flavin_Reduct PF01613.18 KIY73132.1 - 4e-21 75.7 0.5 6.5e-21 75.0 0.5 1.3 1 0 0 1 1 1 1 Flavin reductase like domain Abhydrolase_3 PF07859.13 KIY73135.1 - 4.5e-26 92.0 0.0 6.3e-26 91.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KIY73135.1 - 9.7e-11 41.1 0.0 1.4e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase EthD PF07110.11 KIY73136.1 - 1.8e-12 48.3 0.0 2.2e-12 48.0 0.0 1.1 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 KIY73136.1 - 1.3e-07 32.1 0.0 1.8e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Methylmuconolactone methyl-isomerase Lyase_aromatic PF00221.19 KIY73137.1 - 3.6e-148 494.1 7.2 3.6e-148 494.1 7.2 1.5 2 0 0 2 2 2 1 Aromatic amino acid lyase Mg_trans_NIPA PF05653.14 KIY73138.1 - 7.9e-19 67.9 12.0 5.1e-11 42.2 1.3 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 KIY73138.1 - 8.2e-08 32.5 23.0 1.5e-06 28.4 3.9 3.4 3 1 0 3 3 3 2 EamA-like transporter family Pox_Ag35 PF03286.14 KIY73138.1 - 1.2 8.9 6.1 3.3 7.5 6.1 1.7 1 0 0 1 1 1 0 Pox virus Ag35 surface protein SpoIISA_toxin PF14171.6 KIY73138.1 - 3.8 7.2 5.2 6.7 6.3 5.2 1.3 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system Ssl1 PF04056.14 KIY73139.1 - 1.2e-67 227.5 0.0 4.1e-67 225.8 0.0 1.7 1 1 0 1 1 1 1 Ssl1-like C1_4 PF07975.12 KIY73139.1 - 2.1e-15 56.7 9.0 2.1e-15 56.7 9.0 2.5 2 0 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.6 KIY73139.1 - 3.7e-11 43.6 0.0 6.3e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain zf-HIT PF04438.16 KIY73139.1 - 0.055 13.4 0.9 0.055 13.4 0.9 3.8 5 0 0 5 5 5 0 HIT zinc finger IBR PF01485.21 KIY73139.1 - 0.26 11.6 13.5 0.17 12.2 5.8 2.6 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain Tfb4 PF03850.14 KIY73139.1 - 0.3 10.6 6.0 4.5 6.7 6.8 2.1 2 0 0 2 2 2 0 Transcription factor Tfb4 Rad10 PF03834.14 KIY73141.1 - 2.3e-44 150.0 0.0 3.3e-44 149.5 0.0 1.2 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.6 KIY73141.1 - 7.7e-08 32.8 0.0 1.2e-07 32.2 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_2 PF12826.7 KIY73141.1 - 0.006 16.6 0.1 0.024 14.7 0.0 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix motif MMR_HSR1 PF01926.23 KIY73141.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF1746 PF08508.10 KIY73142.1 - 3.9e-12 46.5 1.9 6.8e-12 45.7 1.9 1.4 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) zf-UBR PF02207.20 KIY73143.1 - 6.4e-16 58.3 18.1 6.4e-16 58.3 18.1 2.2 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 KIY73143.1 - 5.8e-10 38.8 0.1 2.3e-09 36.9 0.1 2.0 2 0 0 2 2 2 1 ATP-dependent Clp protease adaptor protein ClpS ELL PF10390.9 KIY73143.1 - 0.026 14.0 0.0 0.053 13.0 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase II elongation factor ELL DUF948 PF06103.11 KIY73143.1 - 0.97 9.7 2.7 73 3.7 0.0 3.4 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) tRNA-synt_1c PF00749.21 KIY73144.1 - 2e-83 279.9 0.0 2.8e-83 279.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1b PF00579.25 KIY73144.1 - 0.16 11.2 0.0 5.3 6.3 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) DZR PF12773.7 KIY73146.1 - 0.034 14.2 0.3 0.071 13.1 0.3 1.5 1 1 0 1 1 1 0 Double zinc ribbon DIL PF01843.19 KIY73147.1 - 0.13 12.6 0.6 0.44 10.8 0.1 2.0 2 0 0 2 2 2 0 DIL domain Transket_pyr PF02779.24 KIY73148.1 - 6.5e-41 140.0 0.1 1.2e-40 139.1 0.0 1.4 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KIY73148.1 - 9.3e-29 99.8 0.0 4.7e-28 97.6 0.0 2.1 2 1 0 2 2 2 1 Transketolase, C-terminal domain WD40 PF00400.32 KIY73149.1 - 4e-08 33.8 10.9 0.014 16.3 0.1 5.2 4 1 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY73149.1 - 0.00025 21.3 0.0 0.59 10.5 0.0 3.3 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 KIY73149.1 - 0.002 16.7 0.0 0.0058 15.2 0.0 1.7 1 1 0 1 1 1 1 Cytochrome D1 heme domain PD40 PF07676.12 KIY73149.1 - 0.067 13.2 1.8 0.19 11.7 0.1 2.7 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat YpsA PF06908.11 KIY73149.1 - 0.23 11.5 0.0 0.37 10.8 0.0 1.3 1 0 0 1 1 1 0 YspA SLOG family adh_short PF00106.25 KIY73150.1 - 6.2e-39 133.5 0.0 9.2e-39 132.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIY73150.1 - 5e-24 85.2 0.0 6.5e-24 84.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KIY73150.1 - 0.00031 20.3 0.0 0.00051 19.6 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KIY73150.1 - 0.00044 20.2 0.1 0.054 13.4 0.0 2.2 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 KIY73150.1 - 0.00064 19.4 0.0 0.019 14.5 0.0 2.0 2 0 0 2 2 2 1 NmrA-like family Staph_haemo PF05480.11 KIY73150.1 - 0.012 15.4 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 Staphylococcus haemolytic protein KR PF08659.10 KIY73150.1 - 0.012 15.6 0.0 0.018 15.0 0.0 1.3 1 0 0 1 1 1 0 KR domain RmlD_sub_bind PF04321.17 KIY73150.1 - 0.024 13.8 0.0 0.036 13.2 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain DUF1776 PF08643.10 KIY73150.1 - 0.08 12.3 0.0 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) CPDase PF07823.11 KIY73151.1 - 3e-12 46.7 0.1 2.1e-11 43.9 0.1 2.1 1 1 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.6 KIY73151.1 - 1.7e-06 28.0 0.0 2e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily AMP-binding PF00501.28 KIY73152.1 - 2.5e-93 313.0 0.0 1e-92 311.0 0.0 1.8 1 1 1 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.6 KIY73152.1 - 1.5e-24 86.8 0.1 3.1e-23 82.5 0.0 2.5 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 KIY73152.1 - 2.4e-14 53.0 1.0 7.2e-14 51.4 1.0 1.9 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus Crp PF00325.20 KIY73152.1 - 0.16 11.7 0.8 0.26 11.0 0.0 1.8 2 0 0 2 2 2 0 Bacterial regulatory proteins, crp family Ras PF00071.22 KIY73153.1 - 5.1e-59 198.5 0.3 6.5e-59 198.2 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIY73153.1 - 2.4e-37 127.8 0.1 3.6e-37 127.2 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIY73153.1 - 5.9e-16 58.4 0.2 7.4e-16 58.1 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KIY73153.1 - 7.2e-07 28.8 0.1 1.5e-06 27.8 0.1 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 KIY73153.1 - 3.9e-06 26.5 0.3 4.2e-05 23.2 0.3 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KIY73153.1 - 1e-05 25.0 0.4 1.3e-05 24.7 0.4 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KIY73153.1 - 1.2e-05 25.4 0.1 4.8e-05 23.4 0.0 1.8 1 1 1 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIY73153.1 - 0.00016 21.6 0.1 0.04 13.8 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 KIY73153.1 - 0.001 18.6 0.4 0.038 13.5 0.4 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KIY73153.1 - 0.052 13.6 0.0 2.4 8.2 0.0 2.6 2 1 1 3 3 3 0 Dynamin family TniB PF05621.11 KIY73153.1 - 0.053 12.9 0.0 0.22 10.9 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein CPT PF07931.12 KIY73153.1 - 0.064 13.1 0.0 0.15 11.9 0.0 1.7 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein PduV-EutP PF10662.9 KIY73153.1 - 0.097 12.4 1.1 0.34 10.6 1.1 2.0 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 KIY73153.1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase_2 PF01637.18 KIY73153.1 - 0.13 12.2 0.0 0.36 10.7 0.0 1.5 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea AAA_16 PF13191.6 KIY73153.1 - 0.15 12.5 0.0 0.24 11.8 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain Sugar_tr PF00083.24 KIY73154.1 - 7.1e-86 288.8 20.4 8.5e-86 288.6 20.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY73154.1 - 4.8e-39 134.3 18.2 4.8e-39 134.3 18.2 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KIY73154.1 - 3.4e-06 25.8 1.4 6e-06 25.0 1.4 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 KIY73154.1 - 0.0082 14.6 3.6 0.027 12.9 0.2 2.4 2 1 0 2 2 2 1 Transmembrane secretion effector BT1 PF03092.16 KIY73154.1 - 0.077 11.2 7.1 1.3 7.1 2.9 2.3 2 0 0 2 2 2 0 BT1 family DUF3792 PF12670.7 KIY73154.1 - 4.3 7.5 20.8 2.2 8.5 5.4 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF3792) SLBP_RNA_bind PF15247.6 KIY73155.1 - 6.4 7.0 7.2 0.48 10.6 1.0 2.3 3 0 0 3 3 3 0 Histone RNA hairpin-binding protein RNA-binding domain Zn_clus PF00172.18 KIY73156.1 - 4.2e-08 33.2 9.7 6.5e-08 32.6 9.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KIY73156.1 - 0.02 13.7 0.2 0.03 13.1 0.2 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain CBFD_NFYB_HMF PF00808.23 KIY73157.1 - 7.4e-07 29.4 0.1 1.4e-06 28.5 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T_C PF15511.6 KIY73157.1 - 0.18 12.0 0.0 0.18 12.0 0.0 1.6 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T histone fold Stealth_CR1 PF17101.5 KIY73158.1 - 1.3e-08 34.4 0.1 2.8e-08 33.3 0.1 1.7 1 0 0 1 1 1 1 Stealth protein CR1, conserved region 1 Stealth_CR2 PF11380.8 KIY73158.1 - 0.00014 22.0 0.0 0.069 13.3 0.0 3.2 3 0 0 3 3 3 1 Stealth protein CR2, conserved region 2 Stealth_CR3 PF17102.5 KIY73158.1 - 0.0025 17.7 0.9 0.006 16.5 0.9 1.7 1 0 0 1 1 1 1 Stealth protein CR3, conserved region 3 Stealth_CR4 PF17103.5 KIY73158.1 - 0.0055 16.6 0.1 0.012 15.5 0.1 1.5 1 0 0 1 1 1 1 Stealth protein CR4, conserved region 4 SH3_9 PF14604.6 KIY73159.1 - 5.8e-05 22.9 0.0 0.00035 20.4 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain Abhydrolase_6 PF12697.7 KIY73160.1 - 0.018 15.7 0.0 0.027 15.1 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family HisG PF01634.18 KIY73163.1 - 4.9e-51 172.9 0.0 6.8e-51 172.4 0.0 1.2 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 KIY73163.1 - 9.7e-29 99.3 0.1 2.7e-28 97.9 0.1 1.8 2 0 0 2 2 2 1 HisG, C-terminal domain NMT1 PF09084.11 KIY73163.1 - 0.00021 21.3 0.0 0.0003 20.8 0.0 1.3 1 0 0 1 1 1 1 NMT1/THI5 like SDA1 PF05285.12 KIY73165.1 - 0.002 17.6 23.6 0.0023 17.4 23.6 1.0 1 0 0 1 1 1 1 SDA1 Troponin-I_N PF11636.8 KIY73165.1 - 0.023 14.7 1.0 0.054 13.4 1.0 1.6 1 0 0 1 1 1 0 Troponin I residues 1-32 RNA_pol_Rpc4 PF05132.14 KIY73165.1 - 0.023 15.1 1.6 0.035 14.6 1.6 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 Nop14 PF04147.12 KIY73165.1 - 0.5 8.5 29.7 0.54 8.4 29.7 1.0 1 0 0 1 1 1 0 Nop14-like family CNDH2_C PF16858.5 KIY73165.1 - 0.81 9.5 10.3 1 9.2 10.3 1.2 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term BUD22 PF09073.10 KIY73165.1 - 1.3 8.3 22.6 1.3 8.2 22.6 1.1 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 KIY73165.1 - 1.5 7.0 20.8 1.7 6.8 20.8 1.2 1 0 0 1 1 1 0 CDC45-like protein CobT PF06213.12 KIY73165.1 - 1.6 8.1 26.6 1.9 7.8 26.6 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF913 PF06025.12 KIY73165.1 - 2.1 7.2 4.7 2.4 7.0 4.7 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Na_trans_assoc PF06512.13 KIY73165.1 - 4 7.7 14.3 5.1 7.3 14.3 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated TFIIA PF03153.13 KIY73165.1 - 4.3 7.2 28.2 4.5 7.2 28.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DNA_pol_phi PF04931.13 KIY73165.1 - 9.5 4.2 39.8 13 3.7 39.8 1.2 1 0 0 1 1 1 0 DNA polymerase phi TFIIA PF03153.13 KIY73166.1 - 0.0029 17.7 13.4 0.0031 17.6 13.4 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Coilin_N PF15862.5 KIY73166.1 - 0.0071 16.2 2.2 0.013 15.3 2.2 1.4 1 0 0 1 1 1 1 Coilin N-terminus Spt20 PF12090.8 KIY73166.1 - 0.015 14.9 16.4 0.019 14.6 16.4 1.2 1 0 0 1 1 1 0 Spt20 family DUF2722 PF10846.8 KIY73166.1 - 0.023 13.7 10.6 0.035 13.1 10.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF3801 PF12687.7 KIY73166.1 - 0.04 14.0 4.6 0.054 13.6 4.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) Spem1 PF15670.5 KIY73166.1 - 0.044 13.4 3.9 0.058 13.0 3.9 1.1 1 0 0 1 1 1 0 Spermatid maturation protein 1 Med3 PF11593.8 KIY73166.1 - 0.11 11.6 9.5 0.15 11.2 9.5 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Suf PF05843.14 KIY73166.1 - 0.37 10.7 7.0 0.5 10.3 7.0 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Activator_LAG-3 PF11498.8 KIY73166.1 - 0.44 9.5 25.3 0.62 9.0 25.3 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DUF3499 PF12005.8 KIY73166.1 - 0.46 11.1 4.9 0.84 10.3 4.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3499) DUF5349 PF17298.2 KIY73166.1 - 0.66 9.7 6.9 1.1 9.0 6.9 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5349) OmpH PF03938.14 KIY73166.1 - 0.68 10.3 15.6 0.97 9.8 15.6 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) RR_TM4-6 PF06459.12 KIY73166.1 - 0.69 9.7 4.9 1 9.1 4.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 KIY73166.1 - 0.86 8.3 5.8 1 8.1 5.8 1.1 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.10 KIY73166.1 - 1.2 7.8 4.0 1.2 7.7 4.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Ctr PF04145.15 KIY73166.1 - 1.7 9.3 4.2 3 8.4 4.2 1.3 1 0 0 1 1 1 0 Ctr copper transporter family eIF-3_zeta PF05091.12 KIY73166.1 - 2.1 7.2 9.3 2.8 6.8 9.3 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) AIM3 PF17096.5 KIY73166.1 - 6.3 7.8 11.4 29 5.7 7.0 2.2 2 0 0 2 2 2 0 Altered inheritance of mitochondria protein 3 Pex14_N PF04695.13 KIY73166.1 - 6.9 7.3 19.4 10 6.8 19.3 1.5 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4834 PF16118.5 KIY73166.1 - 7.6 7.6 10.2 15 6.6 10.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) PI3_PI4_kinase PF00454.27 KIY73167.1 - 5.9e-34 118.0 0.2 1.8e-31 109.8 0.1 2.8 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 KIY73167.1 - 2.2e-24 85.9 0.0 6.1e-24 84.4 0.0 1.7 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Thioredoxin_13 PF18401.1 KIY73167.1 - 0.051 13.5 0.3 3.6 7.5 0.0 3.1 3 0 0 3 3 3 0 Thioredoxin-like domain DUF4135 PF13575.6 KIY73167.1 - 0.057 12.7 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) Adaptin_N PF01602.20 KIY73167.1 - 0.074 11.6 0.1 0.78 8.2 0.0 2.3 2 0 0 2 2 2 0 Adaptin N terminal region MapZ_EC1 PF18041.1 KIY73168.1 - 0.00042 20.6 0.7 0.00082 19.6 0.7 1.4 1 0 0 1 1 1 1 MapZ extracellular domain 1 FAD_SOX PF18371.1 KIY73168.1 - 0.026 14.9 0.2 0.22 11.9 0.1 2.2 1 1 0 2 2 2 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase Nefa_Nip30_N PF10187.9 KIY73168.1 - 0.036 14.4 1.3 0.036 14.4 1.3 1.6 2 0 0 2 2 2 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 APH PF01636.23 KIY73169.1 - 1.3e-09 38.3 1.7 2.4e-08 34.2 1.7 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KIY73169.1 - 0.0024 17.5 0.0 0.0068 16.0 0.0 1.6 2 0 0 2 2 2 1 Choline/ethanolamine kinase Pkinase PF00069.25 KIY73169.1 - 0.0046 16.4 0.0 0.0079 15.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 KIY73169.1 - 0.013 15.1 0.1 0.052 13.1 0.0 1.8 2 0 0 2 2 2 0 RIO1 family Polyketide_cyc2 PF10604.9 KIY73170.1 - 0.014 15.6 0.1 0.021 15.1 0.1 1.3 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport RIO1 PF01163.22 KIY73171.1 - 1e-66 224.2 0.0 1e-66 224.2 0.0 2.0 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.14 KIY73171.1 - 0.00069 19.0 4.3 0.14 11.4 1.1 3.1 2 1 1 3 3 3 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KIY73171.1 - 0.006 16.0 0.0 0.006 16.0 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain RSN1_7TM PF02714.15 KIY73172.1 - 3.1e-79 266.1 24.9 3.1e-79 266.1 24.9 1.6 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 KIY73172.1 - 2.1e-37 129.0 0.0 3e-37 128.5 0.0 1.2 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 KIY73172.1 - 1.1e-33 116.3 2.7 1.1e-33 116.3 2.7 2.6 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport Macro PF01661.21 KIY73173.1 - 9.4e-39 132.1 0.2 1.6e-38 131.4 0.2 1.4 1 0 0 1 1 1 1 Macro domain MFS_1 PF07690.16 KIY73174.1 - 7e-10 38.4 36.6 5.2e-09 35.5 20.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.16 KIY73174.1 - 2e-06 27.6 2.4 2e-06 27.6 2.4 2.0 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Peptidase_S8 PF00082.22 KIY73175.1 - 2.1e-36 125.7 3.2 3.2e-36 125.1 3.2 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 KIY73175.1 - 1e-24 86.3 0.5 2e-24 85.4 0.5 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain Peptidase_S8_N PF16361.5 KIY73175.1 - 0.042 14.3 0.1 0.3 11.6 0.0 2.0 1 1 1 2 2 2 0 N-terminal of Subtilase family Alpha_GJ PF03229.13 KIY73175.1 - 0.076 13.6 0.2 0.076 13.6 0.2 2.5 2 0 0 2 2 2 0 Alphavirus glycoprotein J DUF5310 PF17237.2 KIY73176.1 - 1.8e-16 59.7 2.5 2.8e-16 59.1 2.5 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5310) zf-NADH-PPase PF09297.11 KIY73177.1 - 0.14 11.8 1.2 0.28 10.9 1.2 1.4 1 0 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain Ribosomal_L22e PF01776.17 KIY73178.1 - 1.3e-47 160.7 1.1 1.5e-47 160.4 1.1 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family AdoMet_Synthase PF01941.19 KIY73178.1 - 0.011 14.6 0.1 0.012 14.4 0.1 1.0 1 0 0 1 1 1 0 S-adenosylmethionine synthetase (AdoMet synthetase) DUF4845 PF16137.5 KIY73178.1 - 0.05 14.5 0.1 0.083 13.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4845) Sybindin PF04099.12 KIY73179.1 - 3e-40 137.5 0.0 3.6e-40 137.2 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 KIY73179.1 - 3.6e-08 33.6 0.0 4.2e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Methyltransf_18 PF12847.7 KIY73179.1 - 0.095 12.6 0.0 0.26 11.2 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Peptidase_M28 PF04389.17 KIY73180.1 - 5e-38 130.8 0.4 1.3e-37 129.5 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M28 Lipase_3 PF01764.25 KIY73181.1 - 2.3e-15 56.7 0.0 4.1e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Macro PF01661.21 KIY73182.1 - 3.8e-18 65.6 0.2 6.7e-18 64.8 0.3 1.4 2 0 0 2 2 2 1 Macro domain Fungal_trans PF04082.18 KIY73183.1 - 2e-20 72.9 0.0 3.3e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY73183.1 - 4.3e-08 33.1 12.5 7.5e-08 32.4 12.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box-like PF12937.7 KIY73184.1 - 4.6e-10 39.2 0.1 2.2e-09 37.0 0.1 2.1 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 KIY73185.1 - 3.9e-08 33.1 0.0 1.6e-07 31.1 0.0 2.0 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KIY73185.1 - 0.006 16.4 2.8 0.16 11.9 2.8 2.6 1 1 0 1 1 1 1 F-box domain REPA_OB_2 PF16900.5 KIY73186.1 - 0.082 12.8 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Replication protein A OB domain APG9 PF04109.16 KIY73187.1 - 2.7e-204 679.6 6.9 3.1e-204 679.4 6.9 1.0 1 0 0 1 1 1 1 Autophagy protein Apg9 TRAM_LAG1_CLN8 PF03798.16 KIY73189.1 - 0.00077 19.2 17.6 0.0047 16.7 17.6 1.9 1 1 0 1 1 1 1 TLC domain DUF1211 PF06736.11 KIY73189.1 - 2.2 8.8 12.2 6.3 7.3 2.0 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1211) tRNA-synt_1c PF00749.21 KIY73190.1 - 3.6e-108 361.2 0.0 4.9e-108 360.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 KIY73190.1 - 2.3e-39 135.1 0.9 3.2e-39 134.6 0.2 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.6 KIY73190.1 - 4.1e-05 23.7 0.1 0.004 17.3 0.0 2.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KIY73190.1 - 0.00017 21.7 0.0 0.00037 20.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KIY73190.1 - 0.00044 20.2 0.0 0.0011 18.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain HMGL-like PF00682.19 KIY73191.1 - 1.9e-68 230.9 0.0 2.7e-68 230.4 0.0 1.2 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 KIY73191.1 - 3.6e-43 146.7 0.0 1.1e-20 73.9 0.0 2.4 2 0 0 2 2 2 2 LeuA allosteric (dimerisation) domain Ribosomal_L7Ae PF01248.26 KIY73192.1 - 5.9e-27 93.2 2.9 7.3e-27 93.0 2.9 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Git3 PF11710.8 KIY73194.1 - 3.8e-07 30.1 12.3 1.3e-06 28.3 12.3 1.8 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.21 KIY73194.1 - 9.4e-06 25.1 9.8 1.4e-05 24.6 9.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Dicty_CAR PF05462.11 KIY73194.1 - 0.0018 17.5 7.7 0.0028 16.9 7.7 1.3 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor GPR_Gpa2_C PF11970.8 KIY73194.1 - 0.031 14.4 0.4 0.031 14.4 0.4 2.7 3 1 1 4 4 4 0 G protein-coupled glucose receptor regulating Gpa2 C-term Phage_holin_3_6 PF07332.11 KIY73194.1 - 9 6.4 12.8 0.9 9.6 1.7 3.1 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III Pro_CA PF00484.19 KIY73195.1 - 1.7e-31 109.6 0.0 2.1e-31 109.3 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase AAA PF00004.29 KIY73196.1 - 6.2e-94 311.4 0.0 5.5e-48 162.7 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KIY73196.1 - 3.3e-20 71.6 0.3 1.1e-09 37.9 0.6 2.7 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 KIY73196.1 - 3.3e-15 56.2 0.0 1.3e-07 31.5 0.0 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KIY73196.1 - 5.2e-13 49.7 1.3 0.00024 21.5 0.0 4.7 3 2 1 4 4 3 2 AAA ATPase domain AAA_5 PF07728.14 KIY73196.1 - 9.5e-12 45.1 0.4 0.00047 20.2 0.0 4.0 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KIY73196.1 - 5.2e-11 43.0 1.1 0.024 14.9 0.0 5.3 3 2 2 6 6 6 2 AAA domain AAA_2 PF07724.14 KIY73196.1 - 2.1e-10 41.0 0.0 0.00086 19.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 KIY73196.1 - 4e-10 40.0 0.0 0.00028 21.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 KIY73196.1 - 1.4e-08 35.0 0.0 0.014 15.8 0.0 3.3 3 1 0 3 3 2 2 RNA helicase TIP49 PF06068.13 KIY73196.1 - 2e-08 33.8 0.0 0.00037 19.8 0.0 2.4 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_14 PF13173.6 KIY73196.1 - 1.6e-07 31.4 0.0 0.025 14.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 KIY73196.1 - 4.4e-07 29.5 1.4 0.029 13.7 0.4 2.7 2 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KIY73196.1 - 4.5e-07 29.8 0.0 0.017 14.9 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_28 PF13521.6 KIY73196.1 - 1.9e-06 28.2 0.0 0.045 14.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_3 PF07726.11 KIY73196.1 - 5.1e-06 26.4 0.0 0.013 15.3 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 KIY73196.1 - 7.8e-06 26.4 0.0 0.22 12.0 0.0 3.1 2 1 0 2 2 2 2 ABC transporter NACHT PF05729.12 KIY73196.1 - 1.4e-05 25.1 0.4 0.44 10.4 0.0 3.5 2 1 1 3 3 3 2 NACHT domain TsaE PF02367.17 KIY73196.1 - 1.5e-05 25.0 0.0 0.22 11.5 0.0 2.3 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 KIY73196.1 - 2.7e-05 24.7 0.0 0.28 11.7 0.0 2.6 2 1 0 2 2 2 2 AAA domain Rad17 PF03215.15 KIY73196.1 - 4e-05 23.6 0.0 0.15 12.0 0.0 2.4 2 0 0 2 2 2 2 Rad17 P-loop domain Sigma54_activat PF00158.26 KIY73196.1 - 4.2e-05 23.3 0.0 0.33 10.6 0.0 3.3 2 2 0 2 2 2 2 Sigma-54 interaction domain ATPase PF06745.13 KIY73196.1 - 4.8e-05 22.8 0.1 1.5 8.1 0.0 3.3 2 1 0 3 3 3 2 KaiC AAA_25 PF13481.6 KIY73196.1 - 8.8e-05 22.2 2.8 0.96 9.0 0.1 4.1 3 1 1 4 4 4 2 AAA domain AAA_17 PF13207.6 KIY73196.1 - 9.8e-05 22.8 0.0 0.15 12.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KIY73196.1 - 0.0001 21.9 0.0 0.69 9.4 0.0 2.7 2 1 0 2 2 2 2 P-loop containing dynein motor region Zeta_toxin PF06414.12 KIY73196.1 - 0.00011 21.5 0.0 0.57 9.4 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin Cytidylate_kin2 PF13189.6 KIY73196.1 - 0.00012 22.3 0.0 0.073 13.2 0.0 2.3 2 0 0 2 2 2 1 Cytidylate kinase-like family DUF815 PF05673.13 KIY73196.1 - 0.00015 21.1 0.0 0.011 14.9 0.0 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF815) Sigma54_activ_2 PF14532.6 KIY73196.1 - 0.00042 20.4 0.0 2.2 8.4 0.0 3.0 3 0 0 3 3 3 2 Sigma-54 interaction domain NB-ARC PF00931.22 KIY73196.1 - 0.001 18.3 0.1 0.88 8.7 0.0 2.7 3 0 0 3 3 3 1 NB-ARC domain SKI PF01202.22 KIY73196.1 - 0.0011 19.1 0.0 1.2 9.3 0.0 2.6 2 0 0 2 2 2 1 Shikimate kinase Viral_helicase1 PF01443.18 KIY73196.1 - 0.0012 18.7 0.0 0.54 10.0 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase PhoH PF02562.16 KIY73196.1 - 0.0012 18.4 0.2 1.7 8.0 0.1 2.4 2 0 0 2 2 2 2 PhoH-like protein AAA_24 PF13479.6 KIY73196.1 - 0.0013 18.5 0.0 0.89 9.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 KIY73196.1 - 0.0014 18.6 0.0 1.9 8.3 0.0 3.6 2 2 2 4 4 4 1 ATPase domain predominantly from Archaea AAA_11 PF13086.6 KIY73196.1 - 0.0014 18.5 0.0 2.2 8.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain Parvo_NS1 PF01057.17 KIY73196.1 - 0.005 16.0 0.1 1.7 7.6 0.0 2.2 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 Vps4_C PF09336.10 KIY73196.1 - 0.011 15.7 0.1 2 8.5 0.0 2.8 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain SAT PF16073.5 KIY73196.1 - 0.028 14.2 0.3 0.16 11.6 0.4 2.2 2 0 0 2 2 2 0 Starter unit:ACP transacylase in aflatoxin biosynthesis DUF2075 PF09848.9 KIY73196.1 - 0.029 13.6 0.1 3.3 6.8 0.0 2.4 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 KIY73196.1 - 0.048 14.0 0.6 21 5.4 0.0 3.0 2 1 0 2 2 2 0 AAA domain AFG1_ATPase PF03969.16 KIY73196.1 - 0.052 12.4 0.0 3.4 6.5 0.0 2.2 2 0 0 2 2 2 0 AFG1-like ATPase Bac_DnaA PF00308.18 KIY73196.1 - 0.057 13.3 0.0 4.1 7.2 0.0 2.5 2 1 0 2 2 2 0 Bacterial dnaA protein PduV-EutP PF10662.9 KIY73196.1 - 0.061 13.1 0.0 11 5.8 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.15 KIY73196.1 - 0.073 13.0 0.2 6.1 6.7 0.0 2.8 3 0 0 3 3 2 0 NTPase Cytidylate_kin PF02224.18 KIY73196.1 - 0.098 12.4 0.0 7.9 6.1 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase CPT PF07931.12 KIY73196.1 - 0.1 12.4 0.0 2.8 7.7 0.0 2.5 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein IPT PF01745.16 KIY73196.1 - 0.18 11.1 0.0 15 4.9 0.0 2.2 2 0 0 2 2 2 0 Isopentenyl transferase Ribosomal_L30 PF00327.20 KIY73197.1 - 1.6e-12 47.1 0.2 2.4e-12 46.6 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e DUF3533 PF12051.8 KIY73198.1 - 6.1e-89 298.6 11.8 8.3e-89 298.1 11.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) OEP PF02321.18 KIY73198.1 - 0.018 14.9 0.1 0.034 14.0 0.1 1.4 1 0 0 1 1 1 0 Outer membrane efflux protein F-box-like PF12937.7 KIY73199.1 - 0.038 13.9 3.5 1.2 9.1 0.2 2.5 2 0 0 2 2 2 0 F-box-like Glyco_trans_4_4 PF13579.6 KIY73199.1 - 7.8 6.9 7.6 0.41 11.1 1.2 2.1 2 2 0 2 2 2 0 Glycosyl transferase 4-like domain LCM PF04072.14 KIY73200.1 - 1.7e-20 73.8 0.0 3.1e-20 72.9 0.0 1.4 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Thiamine_BP PF01910.17 KIY73201.1 - 4.1e-26 90.7 0.0 4.9e-26 90.5 0.0 1.1 1 0 0 1 1 1 1 Thiamine-binding protein Ykof PF07615.11 KIY73201.1 - 0.00079 19.8 0.0 0.0011 19.4 0.0 1.2 1 0 0 1 1 1 1 YKOF-related Family DUF3580 PF12117.8 KIY73201.1 - 0.15 12.3 0.0 0.22 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3580) DUF4451 PF14616.6 KIY73202.1 - 0.002 18.3 5.1 1.4 9.1 0.0 3.4 3 0 0 3 3 3 3 Domain of unknown function (DUF4451) S8_pro-domain PF16470.5 KIY73202.1 - 0.1 13.4 0.5 33 5.3 0.0 3.6 3 0 0 3 3 3 0 Peptidase S8 pro-domain DZR PF12773.7 KIY73202.1 - 8.9 6.4 8.2 18 5.5 1.8 3.2 3 1 0 3 3 3 0 Double zinc ribbon Mito_carr PF00153.27 KIY73203.1 - 3.2e-49 164.8 3.7 1.2e-17 63.6 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KIY73203.1 - 0.016 14.4 1.2 1 8.4 0.0 3.0 2 2 1 3 3 3 0 Gammaproteobacterial serine protease DNA_methylase PF00145.17 KIY73204.1 - 6.2e-49 167.1 0.0 2.9e-48 164.9 0.0 2.1 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase BAH PF01426.18 KIY73204.1 - 2.5e-10 40.2 0.1 2.4e-08 33.9 0.1 2.4 2 0 0 2 2 2 2 BAH domain DNMT1-RFD PF12047.8 KIY73204.1 - 1.5e-08 34.8 0.0 2.7e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Cytosine specific DNA methyltransferase replication foci domain DUF2484 PF10658.9 KIY73205.1 - 7.9 6.9 7.4 0.98 9.8 3.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2484) MFS_1 PF07690.16 KIY73206.1 - 6.3e-26 91.1 36.9 4.1e-25 88.4 36.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily SpoIISA_toxin PF14171.6 KIY73206.1 - 0.11 12.2 1.5 0.18 11.5 1.5 1.3 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system NPR3 PF03666.13 KIY73207.1 - 5.1e-92 309.1 3.6 1.2e-71 242.0 1.0 2.2 1 1 1 2 2 2 2 Nitrogen Permease regulator of amino acid transport activity 3 NPR2 PF06218.11 KIY73207.1 - 0.039 12.7 0.0 0.095 11.4 0.0 1.6 2 0 0 2 2 2 0 Nitrogen permease regulator 2 DUF4164 PF13747.6 KIY73207.1 - 0.095 13.0 2.0 0.21 11.9 2.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) Pyr_redox_2 PF07992.14 KIY73208.1 - 1.6e-42 145.7 0.1 2.4e-42 145.2 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIY73208.1 - 8.6e-09 35.8 0.2 2.8e-06 27.8 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.32 KIY73208.1 - 1.1e-08 33.9 3.6 0.00048 19.5 0.6 2.7 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KIY73208.1 - 3.4e-08 32.8 1.3 0.00086 19.0 0.1 2.9 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 KIY73208.1 - 5.7e-07 29.9 0.1 0.0031 17.9 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KIY73208.1 - 0.00016 21.0 1.3 0.035 13.6 0.1 2.8 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 KIY73208.1 - 0.00024 20.9 2.6 0.046 13.6 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain pair NAD_binding_9 PF13454.6 KIY73208.1 - 0.0013 18.8 0.4 0.74 9.8 0.0 3.8 4 0 0 4 4 4 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KIY73208.1 - 0.29 10.4 2.7 4.5 6.4 2.6 2.5 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Velvet PF11754.8 KIY73209.1 - 1.8e-44 152.6 7.1 5.2e-30 105.2 0.1 2.9 2 1 1 3 3 3 2 Velvet factor DUF4662 PF15578.6 KIY73209.1 - 0.17 11.7 4.6 0.28 10.9 4.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4662) A_deaminase PF00962.22 KIY73210.1 - 6e-27 94.8 0.0 4.1e-26 92.1 0.0 2.0 2 0 0 2 2 2 1 Adenosine/AMP deaminase A_deaminase_N PF08451.11 KIY73210.1 - 0.00019 21.7 0.0 0.00043 20.5 0.0 1.7 1 0 0 1 1 1 1 Adenosine/AMP deaminase N-terminal Amidohydro_1 PF01979.20 KIY73210.1 - 0.13 11.6 0.0 21 4.3 0.0 2.9 3 0 0 3 3 3 0 Amidohydrolase family DUF3445 PF11927.8 KIY73212.1 - 1.8e-65 220.7 0.0 2.3e-65 220.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) DUF3445 PF11927.8 KIY73213.1 - 1.3e-61 208.2 0.0 1.7e-61 207.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Ring_hydroxyl_A PF00848.19 KIY73214.1 - 3.2e-21 76.3 8.6 1.2e-19 71.1 6.1 2.5 2 1 0 2 2 2 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 KIY73214.1 - 5.1e-15 55.2 0.1 1.1e-14 54.2 0.1 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain WD40 PF00400.32 KIY73215.1 - 3.8e-12 46.5 4.1 0.0012 19.6 0.0 5.9 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY73215.1 - 4.9e-06 26.8 0.0 0.79 10.1 0.0 4.6 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIY73215.1 - 0.015 14.3 0.1 4.4 6.2 0.0 2.9 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Bestrophin PF01062.21 KIY73216.1 - 3.7e-43 148.0 0.0 1e-41 143.3 0.0 2.0 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel S-AdoMet_synt_M PF02772.16 KIY73216.1 - 0.1 12.9 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 S-adenosylmethionine synthetase, central domain SDF PF00375.18 KIY73216.1 - 1.1 8.2 5.8 0.6 9.1 1.5 2.0 2 0 0 2 2 2 0 Sodium:dicarboxylate symporter family RdRP PF05183.12 KIY73217.1 - 9.5e-177 589.2 0.0 1.4e-176 588.6 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase DUF1776 PF08643.10 KIY73218.1 - 7e-13 48.6 0.0 1e-12 48.0 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) IL11 PF07400.11 KIY73218.1 - 0.069 12.8 0.3 0.16 11.6 0.3 1.6 1 0 0 1 1 1 0 Interleukin 11 Arginase PF00491.21 KIY73218.1 - 0.15 11.5 0.1 0.41 10.1 0.0 1.6 2 0 0 2 2 2 0 Arginase family Ammonium_transp PF00909.21 KIY73219.1 - 5.3e-104 348.1 20.2 7.3e-104 347.6 20.2 1.2 1 0 0 1 1 1 1 Ammonium Transporter Family Pro-kuma_activ PF09286.11 KIY73220.1 - 1.3e-37 129.2 0.0 2e-37 128.6 0.0 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KIY73220.1 - 6.9e-06 25.5 0.5 5e-05 22.7 0.0 2.2 1 1 0 2 2 2 1 Subtilase family Prenylcys_lyase PF07156.14 KIY73221.1 - 2.7e-46 158.4 0.0 3.8e-46 157.8 0.0 1.1 1 0 0 1 1 1 1 Prenylcysteine lyase Amino_oxidase PF01593.24 KIY73221.1 - 5.9e-10 39.0 0.0 9.5e-10 38.3 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KIY73221.1 - 1e-05 25.7 0.3 2.8e-05 24.2 0.2 1.9 1 1 1 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KIY73221.1 - 2.9e-05 23.8 1.8 0.00017 21.3 1.8 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KIY73221.1 - 0.015 15.2 0.1 0.19 11.7 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KIY73221.1 - 0.026 13.8 0.0 1.2 8.3 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Glucan_synthase PF02364.15 KIY73221.1 - 0.094 10.9 0.0 0.13 10.4 0.0 1.1 1 0 0 1 1 1 0 1,3-beta-glucan synthase component HI0933_like PF03486.14 KIY73221.1 - 0.16 10.7 0.1 6.1 5.4 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein AAA PF00004.29 KIY73222.1 - 7.8e-14 52.2 0.0 2.1e-13 50.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KIY73222.1 - 8.4e-07 29.1 0.0 1.2e-05 25.3 0.0 2.4 2 1 0 2 2 2 1 Rad17 P-loop domain RuvB_N PF05496.12 KIY73222.1 - 1.1e-06 28.5 0.0 7.8e-06 25.7 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KIY73222.1 - 1e-05 25.5 0.0 3.2e-05 23.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KIY73222.1 - 5.3e-05 23.5 0.0 0.00085 19.6 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.6 KIY73222.1 - 0.00041 20.4 0.0 0.00075 19.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KIY73222.1 - 0.00068 20.1 0.1 0.013 15.9 0.0 2.7 2 1 1 3 3 2 1 AAA ATPase domain AAA_25 PF13481.6 KIY73222.1 - 0.0013 18.4 0.8 0.14 11.7 0.0 2.8 2 1 1 3 3 3 1 AAA domain AAA_33 PF13671.6 KIY73222.1 - 0.0015 18.7 0.0 0.0035 17.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 KIY73222.1 - 0.002 18.4 0.1 0.0058 16.9 0.1 1.8 1 0 0 1 1 1 1 AAA C-terminal domain Phage-MuB_C PF09077.11 KIY73222.1 - 0.0098 15.8 0.0 0.024 14.5 0.0 1.7 1 0 0 1 1 1 1 Mu B transposition protein, C terminal AAA_18 PF13238.6 KIY73222.1 - 0.019 15.5 0.0 0.061 13.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KIY73222.1 - 0.03 13.6 0.0 0.089 12.1 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin AAA_7 PF12775.7 KIY73222.1 - 0.041 13.4 0.0 0.075 12.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 KIY73222.1 - 0.042 13.6 0.0 0.12 12.1 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein TsaE PF02367.17 KIY73222.1 - 0.05 13.6 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 KIY73222.1 - 0.053 13.8 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KIY73222.1 - 0.061 13.0 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KIY73222.1 - 0.066 13.1 0.0 0.16 11.8 0.0 1.6 2 0 0 2 2 1 0 RsgA GTPase Mg_chelatase PF01078.21 KIY73222.1 - 0.074 12.4 0.0 0.31 10.4 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_17 PF13207.6 KIY73222.1 - 0.095 13.1 0.1 0.38 11.2 0.0 2.1 2 0 0 2 2 1 0 AAA domain AAA_2 PF07724.14 KIY73222.1 - 0.1 12.7 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Mss4 PF04421.13 KIY73223.1 - 2.7e-16 59.5 0.0 3.8e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 Mss4 protein MFS_1 PF07690.16 KIY73224.1 - 1.4e-25 90.0 53.5 5.5e-20 71.6 18.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.25 KIY73225.1 - 4.2e-43 147.6 0.0 6.4e-43 147.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY73225.1 - 5.3e-42 143.9 0.1 7.6e-42 143.4 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KIY73225.1 - 0.0027 17.7 0.0 0.02 14.8 0.0 2.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KIY73225.1 - 0.0063 15.5 6.0 0.016 14.2 0.0 2.3 2 0 0 2 2 2 1 Haspin like kinase domain SAP PF02037.27 KIY73225.1 - 0.01 15.5 0.1 0.027 14.2 0.1 1.8 1 0 0 1 1 1 0 SAP domain DUF3835 PF12927.7 KIY73226.1 - 8e-06 26.6 27.7 0.0001 23.1 2.2 6.0 5 2 1 6 6 6 3 Domain of unknown function (DUF3835) DUF572 PF04502.13 KIY73226.1 - 6 6.4 12.1 0.38 10.3 6.6 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF572) KH_8 PF17903.1 KIY73227.1 - 0.001 19.1 0.0 0.002 18.2 0.0 1.4 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 KIY73227.1 - 0.0032 17.3 0.5 0.0071 16.2 0.5 1.6 1 0 0 1 1 1 1 KH domain EthD PF07110.11 KIY73228.1 - 7.5e-13 49.4 0.3 9.3e-13 49.2 0.3 1.1 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 KIY73228.1 - 1.8e-05 25.2 0.2 2.5e-05 24.7 0.2 1.3 1 1 0 1 1 1 1 Methylmuconolactone methyl-isomerase Prenylcys_lyase PF07156.14 KIY73229.1 - 8.5e-70 235.7 0.0 1.1e-69 235.3 0.0 1.1 1 0 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.6 KIY73229.1 - 1e-08 35.3 0.2 2.2e-08 34.2 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KIY73229.1 - 1.3e-08 34.6 0.1 7.8e-08 32.0 0.1 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 KIY73229.1 - 6.1e-06 26.1 1.3 0.00022 20.9 1.3 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIY73229.1 - 0.041 13.1 0.1 0.12 11.5 0.1 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KIY73229.1 - 0.047 13.7 0.0 2.6 8.0 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KIY73229.1 - 0.056 12.7 0.0 0.46 9.7 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KIY73229.1 - 0.83 8.8 2.3 5.5 6.2 0.5 2.6 3 0 0 3 3 3 0 Thi4 family MFS_1 PF07690.16 KIY73233.1 - 9.2e-29 100.5 46.0 6.9e-16 58.1 19.4 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIY73233.1 - 1.1e-21 77.3 18.3 2.4e-20 72.8 3.9 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter CFEM PF05730.11 KIY73234.1 - 8.7e-13 48.2 12.3 1.4e-12 47.5 12.3 1.3 1 0 0 1 1 1 1 CFEM domain TIL PF01826.17 KIY73234.1 - 0.35 11.2 6.7 0.67 10.3 6.7 1.4 1 0 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain ABC_membrane PF00664.23 KIY73235.1 - 6.5e-105 350.7 27.9 3.6e-53 181.0 11.1 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KIY73235.1 - 1.2e-65 220.2 0.0 4.2e-32 111.5 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KIY73235.1 - 5.9e-14 52.0 0.0 7.3e-05 22.3 0.0 3.7 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 KIY73235.1 - 2.7e-07 29.8 0.3 0.01 14.6 0.0 2.3 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_22 PF13401.6 KIY73235.1 - 2.1e-06 28.1 0.4 0.16 12.3 0.0 3.9 2 2 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 KIY73235.1 - 6.1e-06 25.6 0.0 0.023 14.0 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_29 PF13555.6 KIY73235.1 - 1.1e-05 25.1 0.2 0.048 13.4 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 KIY73235.1 - 2.1e-05 24.5 0.2 1.1 9.0 0.1 3.9 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KIY73235.1 - 7.1e-05 23.3 2.0 0.041 14.3 0.1 3.0 2 1 0 2 2 2 2 AAA ATPase domain AAA PF00004.29 KIY73235.1 - 0.0014 19.0 1.0 2.1 8.7 0.1 3.9 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KIY73235.1 - 0.0015 18.3 5.4 0.4 10.4 0.1 3.8 3 2 0 3 3 2 2 AAA domain G-alpha PF00503.20 KIY73235.1 - 0.0016 17.7 0.0 1.3 8.1 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit AAA_15 PF13175.6 KIY73235.1 - 0.0036 17.1 0.0 0.28 10.9 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 KIY73235.1 - 0.0037 17.2 0.0 2.7 7.9 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_5 PF07728.14 KIY73235.1 - 0.0054 16.7 0.1 4.6 7.3 0.0 3.9 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 KIY73235.1 - 0.0058 17.2 0.0 0.83 10.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 KIY73235.1 - 0.012 15.4 0.0 1.6 8.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KIY73235.1 - 0.013 15.7 0.3 2.6 8.3 0.0 3.0 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KIY73235.1 - 0.03 14.9 0.0 12 6.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KIY73235.1 - 0.03 13.8 0.0 1.3 8.5 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_25 PF13481.6 KIY73235.1 - 0.034 13.7 0.1 8.4 5.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KIY73235.1 - 0.037 14.2 0.0 13 6.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 KIY73235.1 - 0.038 14.1 0.6 2.7 8.0 0.1 2.8 3 0 0 3 3 2 0 Helicase HerA, central domain SbcCD_C PF13558.6 KIY73235.1 - 0.094 13.0 5.8 5.8 7.2 0.4 4.1 3 2 0 3 3 2 0 Putative exonuclease SbcCD, C subunit APS_kinase PF01583.20 KIY73235.1 - 0.1 12.5 0.1 2.2 8.2 0.0 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase DUF815 PF05673.13 KIY73235.1 - 0.12 11.5 0.0 15 4.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Rad17 PF03215.15 KIY73235.1 - 0.14 12.1 0.0 1.4 8.8 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain RNA_helicase PF00910.22 KIY73235.1 - 0.18 12.2 0.0 13 6.2 0.0 2.9 2 0 0 2 2 2 0 RNA helicase Glyco_transf_22 PF03901.17 KIY73236.1 - 5e-79 266.5 20.8 7.5e-79 265.9 20.8 1.2 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Myotub-related PF06602.14 KIY73237.1 - 1.9e-147 490.8 0.1 2.4e-147 490.5 0.1 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.6 KIY73237.1 - 0.05 13.6 0.0 0.13 12.2 0.0 1.6 2 0 0 2 2 2 0 Tyrosine phosphatase family Y_phosphatase PF00102.27 KIY73237.1 - 0.17 11.4 0.0 0.36 10.4 0.0 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase S-AdoMet_synt_C PF02773.16 KIY73238.1 - 4e-65 218.0 0.2 8.2e-65 217.0 0.0 1.6 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 KIY73238.1 - 1.2e-46 157.9 0.0 2.4e-46 156.9 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 KIY73238.1 - 1.1e-44 151.2 0.1 2.1e-44 150.2 0.1 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.19 KIY73238.1 - 0.017 14.0 0.3 0.14 11.0 0.1 2.0 1 1 0 2 2 2 0 S-adenosylmethionine synthetase (AdoMet synthetase) Glyoxal_oxid_N PF07250.11 KIY73239.1 - 6.7e-37 127.0 0.0 7.2e-36 123.6 0.0 2.5 2 1 0 2 2 2 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 KIY73239.1 - 1.3e-22 79.8 0.2 3.7e-22 78.4 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) DUF3446 PF11928.8 KIY73240.1 - 0.11 12.8 3.3 0.62 10.4 0.9 2.4 2 0 0 2 2 2 0 Early growth response N-terminal domain Phage_Gp23 PF10669.9 KIY73240.1 - 0.12 12.7 3.6 0.1 12.9 1.9 1.7 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) DUF1754 PF08555.10 KIY73241.1 - 3.2 8.6 5.7 6.1 7.7 5.7 1.4 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) Thioredoxin PF00085.20 KIY73242.1 - 2.5e-17 62.7 0.0 3.8e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KIY73242.1 - 2.2e-09 37.7 0.0 3.2e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KIY73242.1 - 8.5e-05 22.7 0.0 0.00036 20.7 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.6 KIY73242.1 - 0.00095 19.4 0.0 0.0028 18.0 0.0 1.6 1 1 1 2 2 2 1 Thioredoxin-like Redoxin PF08534.10 KIY73242.1 - 0.037 13.7 0.1 0.09 12.5 0.0 1.7 1 1 0 2 2 2 0 Redoxin TraF PF13728.6 KIY73242.1 - 0.053 13.3 0.0 0.066 13.0 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein AhpC-TSA PF00578.21 KIY73242.1 - 0.18 11.8 0.0 0.28 11.1 0.0 1.3 1 1 0 1 1 1 0 AhpC/TSA family Thioredoxin_9 PF14595.6 KIY73242.1 - 0.18 11.6 0.0 0.25 11.1 0.0 1.4 1 1 0 1 1 1 0 Thioredoxin G-gamma PF00631.22 KIY73243.1 - 5.8e-23 80.7 0.0 6.4e-23 80.5 0.0 1.0 1 0 0 1 1 1 1 GGL domain G-gamma PF00631.22 KIY73244.1 - 1.2e-23 82.8 0.0 1.4e-23 82.7 0.0 1.0 1 0 0 1 1 1 1 GGL domain Csm1_N PF18504.1 KIY73245.1 - 0.018 15.4 4.2 0.018 15.4 4.2 3.1 4 0 0 4 4 4 0 Csm1 N-terminal domain Phlebovirus_NSM PF07246.11 KIY73245.1 - 0.018 14.4 13.7 0.41 10.0 4.8 2.2 2 0 0 2 2 2 0 Phlebovirus nonstructural protein NS-M DUF4407 PF14362.6 KIY73245.1 - 0.026 13.9 14.8 0.0092 15.4 10.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) APG6_N PF17675.1 KIY73245.1 - 0.029 14.9 4.3 0.029 14.9 4.3 3.7 3 1 0 3 3 3 0 Apg6 coiled-coil region Phage_GP20 PF06810.11 KIY73245.1 - 1.2 9.0 20.3 1.1 9.1 0.8 3.5 2 1 2 4 4 4 0 Phage minor structural protein GP20 PRKG1_interact PF15898.5 KIY73245.1 - 3 8.8 40.0 0.07 14.0 11.8 4.3 2 1 2 4 4 4 0 cGMP-dependent protein kinase interacting domain COG5 PF10392.9 KIY73245.1 - 4.2 7.5 12.6 0.2 11.9 2.3 2.9 3 0 0 3 3 3 0 Golgi transport complex subunit 5 SlyX PF04102.12 KIY73246.1 - 0.031 14.9 6.5 0.05 14.2 0.3 2.4 2 0 0 2 2 2 0 SlyX Aida_N PF08910.10 KIY73246.1 - 0.078 13.4 1.2 0.66 10.4 0.0 2.2 2 0 0 2 2 2 0 Aida N-terminus DUF4407 PF14362.6 KIY73246.1 - 0.46 9.8 4.5 0.65 9.3 4.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TolA_bind_tri PF16331.5 KIY73246.1 - 0.55 10.3 10.6 1.4 9.0 0.6 2.6 3 0 0 3 3 3 0 TolA binding protein trimerisation Wbp11 PF09429.10 KIY73246.1 - 5.7 7.4 7.2 14 6.2 2.1 2.3 1 1 0 2 2 2 0 WW domain binding protein 11 F-box-like PF12937.7 KIY73247.1 - 1e-08 34.9 0.8 2.6e-08 33.6 0.8 1.7 1 0 0 1 1 1 1 F-box-like DUF1768 PF08719.11 KIY73248.1 - 4e-16 59.7 0.0 6.2e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) IF-2B PF01008.17 KIY73249.1 - 2e-63 214.2 0.0 2.5e-63 213.9 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family DSPc PF00782.20 KIY73250.1 - 1.5e-06 28.0 0.0 1.9e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KIY73250.1 - 0.00014 21.5 0.0 0.00019 21.1 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KIY73250.1 - 0.00019 21.5 0.0 0.0003 21.0 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate CDKN3 PF05706.12 KIY73250.1 - 0.0019 17.9 0.0 0.0029 17.3 0.0 1.4 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase3 PF13350.6 KIY73250.1 - 0.018 15.0 0.0 0.039 13.9 0.0 1.5 1 1 0 1 1 1 0 Tyrosine phosphatase family Kelch_4 PF13418.6 KIY73251.1 - 2.8e-30 104.1 6.5 2.8e-06 27.3 0.0 6.4 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 KIY73251.1 - 2.2e-27 94.8 10.7 1.3e-07 31.7 0.0 6.3 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_6 PF13964.6 KIY73251.1 - 2.9e-19 68.6 10.0 3.7e-06 27.0 0.3 5.2 4 1 1 5 5 5 3 Kelch motif DUF4110 PF13422.6 KIY73251.1 - 3e-19 68.9 0.1 3e-19 68.9 0.1 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF4110) Kelch_1 PF01344.25 KIY73251.1 - 2.5e-18 65.4 9.1 1.9e-06 27.3 0.1 5.5 5 1 0 5 5 5 4 Kelch motif Kelch_5 PF13854.6 KIY73251.1 - 8.6e-16 57.5 7.3 0.00074 19.4 0.0 5.6 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.15 KIY73251.1 - 9e-12 44.5 13.4 3.7e-06 26.7 0.2 5.4 5 1 0 5 5 5 3 Kelch motif Na_trans_assoc PF06512.13 KIY73251.1 - 0.02 15.1 5.4 0.035 14.4 5.4 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated FAM176 PF14851.6 KIY73251.1 - 0.051 13.2 13.0 1.2 8.8 0.2 2.5 2 0 0 2 2 2 0 FAM176 family CNDH2_C PF16858.5 KIY73251.1 - 0.52 10.1 10.9 3.3 7.5 0.3 2.2 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term RXT2_N PF08595.11 KIY73251.1 - 1 9.4 15.1 3.6 7.6 0.2 2.4 2 0 0 2 2 2 0 RXT2-like, N-terminal CDC45 PF02724.14 KIY73251.1 - 2.9 6.1 14.4 0.25 9.6 8.1 1.9 2 0 0 2 2 2 0 CDC45-like protein NOA36 PF06524.12 KIY73251.1 - 7.8 5.7 22.2 1.6 8.0 14.9 2.3 2 0 0 2 2 2 0 NOA36 protein STT3 PF02516.14 KIY73253.1 - 1e-145 486.5 33.4 4.7e-139 464.5 30.4 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit Na_H_Exchanger PF00999.21 KIY73254.1 - 3.3e-52 177.6 43.1 4.6e-52 177.1 43.1 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Polysacc_deac_2 PF04748.13 KIY73254.1 - 0.092 11.9 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 Divergent polysaccharide deacetylase Trp_syntA PF00290.20 KIY73255.1 - 1.7e-80 269.6 0.4 2.4e-80 269.1 0.4 1.2 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.25 KIY73255.1 - 1.6e-43 149.2 0.1 2.5e-43 148.6 0.1 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme His_biosynth PF00977.21 KIY73255.1 - 0.0033 16.9 0.1 0.0099 15.4 0.1 1.8 1 0 0 1 1 1 1 Histidine biosynthesis protein Asparaginase PF00710.20 KIY73256.1 - 2.2e-56 190.5 0.0 1.6e-55 187.7 0.0 2.1 1 1 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 KIY73256.1 - 2.9e-30 104.8 0.0 5.9e-30 103.8 0.0 1.6 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain Ank_2 PF12796.7 KIY73256.1 - 2.7e-10 40.7 0.0 3.8e-09 37.0 0.0 2.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KIY73256.1 - 2.4e-06 28.0 0.4 0.0002 21.9 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIY73256.1 - 3.3e-06 27.0 0.1 1.3 9.8 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 KIY73256.1 - 5.2e-05 23.5 1.1 0.14 12.6 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KIY73256.1 - 0.00044 20.5 0.4 0.0019 18.4 0.1 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Pox_A_type_inc PF04508.12 KIY73257.1 - 0.002 17.9 1.9 2.9 7.9 0.0 3.2 2 0 0 2 2 2 2 Viral A-type inclusion protein repeat PKcGMP_CC PF16808.5 KIY73257.1 - 0.75 9.7 6.4 11 6.0 2.0 3.2 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Tmemb_cc2 PF10267.9 KIY73257.1 - 3.2 6.8 16.2 0.23 10.5 9.6 2.0 1 1 1 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein PRKG1_interact PF15898.5 KIY73257.1 - 5 8.1 20.4 6.9 7.6 9.1 3.1 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain FUSC PF04632.12 KIY73257.1 - 6.3 5.2 12.5 7.9 4.9 12.5 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family SPC22 PF04573.12 KIY73258.1 - 1.9e-48 164.2 0.0 2.1e-48 164.0 0.0 1.0 1 0 0 1 1 1 1 Signal peptidase subunit DUF3455 PF11937.8 KIY73259.1 - 7.5e-24 84.9 0.0 9.1e-24 84.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) DUF1043 PF06295.12 KIY73260.1 - 0.063 13.3 0.2 0.12 12.4 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) AbiH PF14253.6 KIY73260.1 - 0.076 12.9 2.2 0.078 12.8 2.2 1.4 1 1 0 1 1 1 0 Bacteriophage abortive infection AbiH TRAM_LAG1_CLN8 PF03798.16 KIY73261.1 - 2.8e-29 102.3 14.4 4.3e-29 101.7 14.4 1.3 1 0 0 1 1 1 1 TLC domain GST_C_6 PF17171.4 KIY73262.1 - 4.5e-16 58.4 0.0 1e-15 57.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KIY73262.1 - 0.0026 17.7 0.3 0.0067 16.4 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KIY73262.1 - 0.012 16.3 0.0 0.038 14.7 0.0 1.8 1 1 0 1 1 1 0 Glutathione S-transferase N-terminal domain Tom37 PF10568.9 KIY73262.1 - 0.039 14.3 0.0 0.082 13.2 0.0 1.5 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein DUF3455 PF11937.8 KIY73263.1 - 9.8e-24 84.5 0.1 1.5e-23 83.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) Metallophos PF00149.28 KIY73264.1 - 2.1e-09 38.2 3.5 2.8e-08 34.5 2.8 2.3 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KIY73264.1 - 7.6e-05 23.0 0.0 0.0043 17.3 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain Sde2_N_Ubi PF13019.6 KIY73265.1 - 4.7e-51 172.9 0.3 5.9e-51 172.6 0.3 1.1 1 0 0 1 1 1 1 Silencing defective 2 N-terminal ubiquitin domain Ribosomal_L12 PF00542.19 KIY73265.1 - 0.077 13.4 1.6 4.6 7.7 0.8 2.3 2 0 0 2 2 2 0 Ribosomal protein L7/L12 C-terminal domain Syja_N PF02383.18 KIY73266.1 - 2e-76 257.4 0.0 3.2e-76 256.7 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain DUF3533 PF12051.8 KIY73267.1 - 1.5e-71 241.3 16.9 1.9e-71 241.0 16.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) cwf18 PF08315.12 KIY73268.1 - 2.2e-28 99.6 14.6 2.2e-28 99.6 14.6 2.1 2 1 0 2 2 2 1 cwf18 pre-mRNA splicing factor GTP_EFTU PF00009.27 KIY73269.1 - 1.1e-51 175.2 0.0 1.6e-51 174.6 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 KIY73269.1 - 2.2e-44 150.0 0.1 4.1e-44 149.1 0.1 1.5 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 KIY73269.1 - 4.7e-16 58.6 0.0 1.1e-15 57.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KIY73269.1 - 1.3e-08 35.1 0.0 2.5e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KIY73269.1 - 2.5e-06 27.5 0.0 5.2e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.6 KIY73269.1 - 0.00022 21.2 0.0 0.00046 20.2 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II RF3_C PF16658.5 KIY73269.1 - 0.0003 20.6 0.0 0.00054 19.8 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain Ras PF00071.22 KIY73269.1 - 0.00067 19.3 0.0 0.0014 18.2 0.0 1.5 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 KIY73269.1 - 0.0039 16.7 0.0 0.0079 15.6 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit SIS_2 PF13580.6 KIY73269.1 - 0.079 13.0 0.1 0.24 11.4 0.0 1.8 2 0 0 2 2 2 0 SIS domain Med15 PF09606.10 KIY73270.1 - 3.9 6.0 40.1 5.2 5.6 40.1 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Sec34 PF04136.15 KIY73271.1 - 8.9e-49 165.2 0.6 1.9e-48 164.1 0.6 1.6 1 0 0 1 1 1 1 Sec34-like family DUF501 PF04417.12 KIY73271.1 - 0.017 14.9 0.4 1.7 8.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF501) CALCOCO1 PF07888.11 KIY73271.1 - 0.028 13.3 0.2 0.043 12.7 0.2 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like T2SSF PF00482.23 KIY73271.1 - 0.11 12.5 0.2 0.49 10.3 0.1 2.3 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F DUF4632 PF15451.6 KIY73271.1 - 0.12 12.5 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4632) DUF3456 PF11938.8 KIY73271.1 - 0.15 12.6 0.5 2 8.9 0.3 2.5 2 0 0 2 2 2 0 TLR4 regulator and MIR-interacting MSAP KH_1 PF00013.29 KIY73272.1 - 6.3e-43 144.4 10.3 1.4e-15 56.9 0.5 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KIY73272.1 - 2.9e-15 55.9 8.2 7.2e-06 25.7 0.2 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 KIY73272.1 - 5.3e-06 26.2 1.7 0.4 10.6 0.0 3.3 3 0 0 3 3 3 2 KH domain KH_5 PF13184.6 KIY73272.1 - 0.0052 16.8 7.3 1.6 8.9 0.1 3.5 3 0 0 3 3 3 2 NusA-like KH domain GET2 PF08690.10 KIY73273.1 - 9.9e-10 38.6 1.9 1.6e-08 34.6 1.9 2.2 1 1 0 1 1 1 1 GET complex subunit GET2 SNF2_N PF00176.23 KIY73274.1 - 1.6e-57 194.9 0.0 2.3e-57 194.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KIY73274.1 - 6.5e-17 61.9 0.0 1.3e-16 60.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PHD PF00628.29 KIY73274.1 - 0.00017 21.4 9.7 0.00017 21.4 9.7 2.8 2 1 1 3 3 3 2 PHD-finger HDA2-3 PF11496.8 KIY73274.1 - 0.0035 16.6 0.0 0.025 13.7 0.0 2.1 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 KIY73274.1 - 0.0074 16.1 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ATP_sub_h PF10775.9 KIY73274.1 - 0.13 12.2 0.4 0.43 10.6 0.4 1.8 1 0 0 1 1 1 0 ATP synthase complex subunit h C1_1 PF00130.22 KIY73274.1 - 2.4 8.1 16.3 6.9 6.7 2.5 2.8 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-PHD-like PF15446.6 KIY73274.1 - 4.7 6.8 14.9 0.45 10.1 0.6 2.9 3 1 1 4 4 4 0 PHD/FYVE-zinc-finger like domain Pkinase PF00069.25 KIY73275.1 - 7.8e-07 28.7 0.0 1.9e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KIY73275.1 - 0.00044 19.7 0.0 0.00096 18.6 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIY73275.1 - 0.0019 18.1 0.0 0.79 9.6 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KIY73275.1 - 0.015 14.1 0.0 0.027 13.3 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 KIY73275.1 - 0.016 14.8 0.0 0.032 13.8 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Pkinase_Tyr PF07714.17 KIY73275.1 - 0.019 14.3 0.0 0.034 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase WaaY PF06176.11 KIY73275.1 - 0.15 11.6 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Hat1_N PF10394.9 KIY73276.1 - 4.2e-53 179.8 0.2 6.5e-53 179.2 0.2 1.3 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_1 PF00583.25 KIY73276.1 - 0.0028 17.9 0.0 0.0066 16.7 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family MOZ_SAS PF01853.18 KIY73276.1 - 0.004 16.8 0.1 0.0085 15.8 0.1 1.5 1 0 0 1 1 1 1 MOZ/SAS family Acetyltransf_10 PF13673.7 KIY73276.1 - 0.14 12.1 0.0 0.35 10.8 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Glyco_hydro_12 PF01670.16 KIY73277.1 - 4.3e-42 144.5 14.2 5e-42 144.3 14.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 GED PF02212.18 KIY73278.1 - 2.3e-12 46.9 0.2 3.3e-12 46.4 0.2 1.2 1 0 0 1 1 1 1 Dynamin GTPase effector domain Lyase_1 PF00206.20 KIY73279.1 - 2.2e-20 73.3 0.0 3.2e-20 72.7 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 KIY73279.1 - 4.6e-19 68.7 0.0 1.4e-18 67.2 0.0 1.9 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus DUF4536 PF15055.6 KIY73281.1 - 5.6e-06 26.5 7.5 1.3e-05 25.3 7.5 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4536) F-box-like PF12937.7 KIY73282.1 - 1.2e-09 37.9 1.9 1.2e-09 37.9 1.9 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIY73282.1 - 0.0087 15.9 6.3 0.075 12.9 0.5 2.7 3 0 0 3 3 3 2 F-box domain Kinesin PF00225.23 KIY73283.1 - 1e-107 360.0 0.0 1.6e-107 359.3 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Kinesin_assoc PF16183.5 KIY73283.1 - 2e-40 138.9 8.0 3e-31 109.0 2.4 3.1 2 1 1 3 3 3 2 Kinesin-associated DUF3694 PF12473.8 KIY73283.1 - 6.6e-40 137.3 0.1 1.9e-39 135.8 0.1 1.9 1 0 0 1 1 1 1 Kinesin protein Microtub_bd PF16796.5 KIY73283.1 - 2.2e-21 76.4 0.0 4.7e-21 75.3 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding PH PF00169.29 KIY73283.1 - 7.9e-10 39.2 0.0 2e-09 37.9 0.0 1.7 1 0 0 1 1 1 1 PH domain FHA PF00498.26 KIY73283.1 - 1.9e-07 31.3 0.0 9.4e-07 29.1 0.0 2.3 2 0 0 2 2 2 1 FHA domain KIF1B PF12423.8 KIY73283.1 - 0.00059 20.2 0.1 0.00059 20.2 0.1 2.6 2 0 0 2 2 2 1 Kinesin protein 1B FlxA PF14282.6 KIY73283.1 - 0.36 10.8 0.0 0.36 10.8 0.0 3.2 4 0 0 4 4 4 0 FlxA-like protein HMG_box PF00505.19 KIY73285.1 - 9.9e-16 57.9 4.7 1.8e-15 57.1 4.7 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KIY73285.1 - 2.1e-08 34.6 3.5 5.3e-08 33.4 3.5 1.7 1 0 0 1 1 1 1 HMG-box domain P63C PF10546.9 KIY73285.1 - 0.075 13.6 0.1 0.13 12.9 0.1 1.3 1 0 0 1 1 1 0 P63C domain zf-CCCH_4 PF18044.1 KIY73286.1 - 1.8e-07 30.8 4.8 3.3e-07 30.0 4.8 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KIY73286.1 - 2.5e-06 27.3 6.8 4.1e-06 26.7 6.8 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 KIY73286.1 - 8.2e-06 25.6 5.2 1.3e-05 25.0 5.2 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Med26 PF08711.11 KIY73286.1 - 1.7e-05 24.7 0.1 3.1e-05 23.9 0.1 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Torus PF16131.5 KIY73286.1 - 0.017 15.8 3.0 0.052 14.2 3.0 1.8 1 0 0 1 1 1 0 Torus domain zf-CCCH_3 PF15663.5 KIY73286.1 - 1.8 8.8 3.7 3.3 7.9 3.7 1.4 1 0 0 1 1 1 0 Zinc-finger containing family Arf PF00025.21 KIY73287.1 - 8.4e-65 217.5 0.0 9.5e-65 217.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KIY73287.1 - 7.3e-13 48.4 0.1 1.4e-07 31.0 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 KIY73287.1 - 1.1e-12 48.3 0.0 1.5e-12 47.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KIY73287.1 - 3.1e-11 43.1 0.0 3.6e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 KIY73287.1 - 1e-08 34.8 0.0 1.3e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KIY73287.1 - 8.2e-08 31.9 0.0 1.1e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KIY73287.1 - 4.5e-07 30.0 0.0 7.9e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.19 KIY73287.1 - 0.026 14.1 0.0 0.55 9.8 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 KIY73287.1 - 0.059 13.3 0.1 0.19 11.7 0.1 1.8 1 1 0 1 1 1 0 NACHT domain DUF2025 PF09634.10 KIY73287.1 - 0.13 12.3 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2025) AAA_18 PF13238.6 KIY73287.1 - 0.18 12.4 0.0 0.27 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain CMAS PF02353.20 KIY73288.1 - 7.2e-57 192.8 0.0 9.4e-57 192.4 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 KIY73288.1 - 1.4e-09 38.5 0.0 2.7e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIY73288.1 - 1.2e-08 35.5 0.0 2.2e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIY73288.1 - 1.1e-05 25.3 0.0 1.5e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIY73288.1 - 1.1e-05 25.3 0.0 1.6e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIY73288.1 - 0.00031 21.4 0.0 0.00054 20.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.10 KIY73288.1 - 0.0021 17.8 0.1 0.0047 16.6 0.0 1.6 2 0 0 2 2 2 1 tRNA methyltransferase complex GCD14 subunit MTS PF05175.14 KIY73288.1 - 0.018 14.6 0.0 0.029 13.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain DOT1 PF08123.13 KIY73288.1 - 0.047 13.2 0.0 0.082 12.4 0.0 1.4 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_16 PF10294.9 KIY73288.1 - 0.082 12.6 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase ADH_zinc_N PF00107.26 KIY73288.1 - 0.085 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase PCMT PF01135.19 KIY73288.1 - 0.17 11.6 0.0 0.27 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GTP_EFTU PF00009.27 KIY73291.1 - 6.5e-34 117.2 0.0 7.7e-33 113.7 0.0 2.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 KIY73291.1 - 2.3e-19 69.5 0.0 6.4e-19 68.0 0.0 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 KIY73291.1 - 8.6e-15 54.9 5.3 1.1e-09 38.6 0.0 3.5 3 0 0 3 3 3 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KIY73291.1 - 9.2e-07 28.9 0.1 7.1e-06 26.1 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 KIY73291.1 - 3.7e-06 26.8 0.6 9.7e-06 25.4 0.2 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 4 Roc PF08477.13 KIY73291.1 - 0.00019 21.7 0.0 0.0005 20.3 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 KIY73291.1 - 0.021 14.6 0.0 0.075 12.8 0.0 2.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Ras PF00071.22 KIY73291.1 - 0.1 12.2 0.0 0.44 10.1 0.0 2.2 1 1 0 1 1 1 0 Ras family AAA_22 PF13401.6 KIY73291.1 - 0.13 12.5 1.2 0.94 9.7 0.3 2.7 2 1 0 2 2 2 0 AAA domain Pectinesterase PF01095.19 KIY73292.1 - 5.7e-46 156.6 4.1 7.4e-46 156.2 4.1 1.0 1 0 0 1 1 1 1 Pectinesterase WD40 PF00400.32 KIY73293.1 - 1e-17 64.1 22.1 9.1e-07 29.5 1.3 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY73293.1 - 9.8e-10 38.6 0.3 0.00013 22.2 0.0 4.9 2 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KIY73293.1 - 0.056 12.8 0.0 27 3.9 0.0 3.3 4 0 0 4 4 4 0 WD40-like domain VID27 PF08553.10 KIY73293.1 - 0.28 10.2 0.0 0.45 9.5 0.0 1.3 1 0 0 1 1 1 0 VID27 C-terminal WD40-like domain PD40 PF07676.12 KIY73293.1 - 0.38 10.7 4.5 29 4.8 0.0 4.1 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat WW PF00397.26 KIY73294.1 - 0.034 14.2 0.3 0.073 13.2 0.3 1.6 1 0 0 1 1 1 0 WW domain FixS PF03597.15 KIY73296.1 - 0.9 9.3 4.7 1.8 8.3 4.7 1.5 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type DUF2207 PF09972.9 KIY73298.1 - 0.032 13.0 0.0 0.047 12.4 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Oxidored_q2 PF00420.24 KIY73298.1 - 0.033 13.8 0.2 0.081 12.6 0.0 1.8 2 1 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L DUF4888 PF16229.5 KIY73299.1 - 0.55 10.2 0.0 0.55 10.2 0.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4888) AA_permease_2 PF13520.6 KIY73300.1 - 1e-46 159.7 49.6 1.3e-46 159.3 49.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KIY73300.1 - 3e-25 88.7 40.7 4.1e-25 88.3 40.7 1.0 1 0 0 1 1 1 1 Amino acid permease WW PF00397.26 KIY73301.1 - 1.8e-07 31.1 7.7 3.7e-07 30.1 7.7 1.6 1 0 0 1 1 1 1 WW domain CYSTM PF12734.7 KIY73301.1 - 0.15 12.4 0.7 0.15 12.4 0.7 4.8 2 1 0 2 2 2 0 Cysteine-rich TM module stress tolerance Oxidored_FMN PF00724.20 KIY73305.1 - 9.1e-73 245.5 0.0 1.1e-72 245.2 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.24 KIY73305.1 - 0.15 11.5 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Rad60-SLD PF11976.8 KIY73306.1 - 9.2e-14 51.0 0.0 1e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KIY73306.1 - 8.4e-10 38.3 0.0 9.7e-10 38.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family Zip PF02535.22 KIY73307.1 - 8.1e-51 173.2 2.6 1.7e-49 168.8 2.6 2.2 1 1 0 1 1 1 1 ZIP Zinc transporter Ribosomal_L28e PF01778.17 KIY73308.1 - 4.9e-29 101.4 0.0 5.9e-29 101.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family Glyco_trans_4_3 PF12000.8 KIY73308.1 - 0.14 11.9 0.0 0.15 11.7 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 4 group DUF2235 PF09994.9 KIY73309.1 - 9e-91 304.2 0.0 1.2e-90 303.8 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF1057 PF06342.12 KIY73309.1 - 0.083 11.9 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) CSTF2_hinge PF14327.6 KIY73310.1 - 2.3e-07 31.1 0.6 2.3e-07 31.1 0.6 2.7 3 0 0 3 3 3 1 Hinge domain of cleavage stimulation factor subunit 2 CSTF_C PF14304.6 KIY73310.1 - 1.5e-06 27.7 0.6 1.5e-06 27.7 0.6 3.1 2 1 1 3 3 3 1 Transcription termination and cleavage factor C-terminal Ndc1_Nup PF09531.10 KIY73310.1 - 0.13 11.0 7.5 0.14 10.8 7.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TFIIA PF03153.13 KIY73310.1 - 6.3 6.7 20.0 7.2 6.5 20.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SPATA3 PF15662.5 KIY73310.1 - 8.8 6.9 13.7 13 6.4 13.7 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated protein 3 family Putative_PNPOx PF01243.20 KIY73312.1 - 0.00016 21.8 0.0 0.00028 21.0 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pkinase PF00069.25 KIY73313.1 - 3.4e-57 193.8 0.0 2.9e-48 164.5 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIY73313.1 - 6.8e-21 74.7 0.0 1.8e-10 40.6 0.0 3.1 2 1 0 2 2 2 2 Protein tyrosine kinase FTA2 PF13095.6 KIY73313.1 - 0.00013 21.7 0.0 0.13 11.9 0.0 2.4 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 KIY73313.1 - 0.00074 18.9 0.1 2.9 7.1 0.0 3.0 3 0 0 3 3 3 2 Kinase-like APH PF01636.23 KIY73313.1 - 0.066 13.1 0.2 0.17 11.8 0.2 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family ATG22 PF11700.8 KIY73314.1 - 1.7e-153 511.8 11.5 1.9e-153 511.6 11.5 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 KIY73314.1 - 1.1e-08 34.4 48.2 4.1e-06 26.0 23.0 3.5 2 2 1 3 3 3 3 Major Facilitator Superfamily Photo_RC PF00124.19 KIY73314.1 - 0.025 13.8 4.3 0.16 11.2 0.0 2.6 2 0 0 2 2 2 0 Photosynthetic reaction centre protein Tmemb_161AB PF10268.9 KIY73314.1 - 0.079 11.6 2.6 0.049 12.3 0.6 1.7 2 0 0 2 2 2 0 Predicted transmembrane protein 161AB MFS_1 PF07690.16 KIY73315.1 - 1.6e-34 119.4 44.8 3.9e-34 118.1 44.8 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KIY73315.1 - 8.3e-16 57.5 26.7 1.4e-15 56.8 26.8 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KIY73315.1 - 3.9e-11 42.5 13.2 3.9e-11 42.5 13.2 3.0 2 1 0 2 2 2 1 Sugar (and other) transporter SKN1 PF03935.15 KIY73316.1 - 7.4e-06 24.6 0.0 9.5e-06 24.3 0.0 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) KAR9 PF08580.10 KIY73316.1 - 6.3 5.2 6.5 7 5.1 6.5 1.2 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Pkinase PF00069.25 KIY73317.1 - 2.5e-72 243.4 0.0 2.9e-72 243.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY73317.1 - 1.9e-30 106.1 0.0 3.9e-30 105.0 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KIY73317.1 - 0.019 14.9 0.1 0.035 14.0 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KIY73317.1 - 0.065 12.5 0.0 0.22 10.8 0.0 1.8 1 1 1 2 2 2 0 Kinase-like Haspin_kinase PF12330.8 KIY73317.1 - 0.086 11.8 0.0 1 8.2 0.0 2.2 1 1 0 1 1 1 0 Haspin like kinase domain Fungal_trans PF04082.18 KIY73318.1 - 9.8e-09 34.6 0.0 1.9e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY73318.1 - 0.00017 21.6 6.6 0.00035 20.6 6.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-HIT PF04438.16 KIY73320.1 - 3e-07 30.2 12.3 4.7e-07 29.5 12.3 1.3 1 0 0 1 1 1 1 HIT zinc finger HpaP PF09483.10 KIY73320.1 - 0.14 12.4 0.3 0.29 11.4 0.3 1.5 1 1 0 1 1 1 0 Type III secretion protein (HpaP) zf-B_box PF00643.24 KIY73320.1 - 0.39 10.9 7.7 0.79 9.9 7.7 1.5 1 0 0 1 1 1 0 B-box zinc finger zf-Mss51 PF13824.6 KIY73320.1 - 7.7 6.7 7.8 20 5.4 7.8 1.7 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 FAD_binding_8 PF08022.12 KIY73321.1 - 0.038 14.1 0.0 0.076 13.1 0.0 1.4 1 0 0 1 1 1 0 FAD-binding domain Ferric_reduct PF01794.19 KIY73321.1 - 2.8 8.1 20.2 0.06 13.5 9.0 3.3 1 1 1 2 2 2 0 Ferric reductase like transmembrane component DDHD PF02862.17 KIY73322.1 - 0.53 10.4 8.4 3.1 7.9 7.5 2.0 2 0 0 2 2 2 0 DDHD domain MMR1 PF08505.10 KIY73322.1 - 2 8.6 16.6 11 6.2 11.3 2.2 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein Npa1 PF11707.8 KIY73323.1 - 7.4e-98 328.0 0.0 2.4e-97 326.4 0.0 2.0 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 KIY73323.1 - 7.5e-52 175.8 0.2 2.5e-51 174.1 0.2 2.0 1 0 0 1 1 1 1 Nucleolar pre-ribosomal-associated protein 1 Creb_binding PF09030.10 KIY73323.1 - 1.6e-05 25.6 0.0 0.00012 22.7 0.0 2.6 2 0 0 2 2 2 1 Creb binding Mannosyl_trans2 PF04188.13 KIY73324.1 - 1.5e-40 139.9 34.9 2.6e-36 125.9 34.9 3.4 1 1 0 1 1 1 1 Mannosyltransferase (PIG-V) Dynactin PF12455.8 KIY73325.1 - 2e-79 266.9 3.5 2e-79 266.9 3.5 3.0 3 0 0 3 3 3 1 Dynein associated protein CAP_GLY PF01302.25 KIY73325.1 - 1e-19 70.3 0.6 4.6e-19 68.2 0.8 1.9 2 0 0 2 2 2 1 CAP-Gly domain Raptor_N PF14538.6 KIY73326.1 - 7e-61 204.5 0.0 1.4e-60 203.5 0.0 1.6 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.32 KIY73326.1 - 2.7e-06 28.0 16.1 0.00071 20.3 0.1 6.8 8 0 0 8 8 8 2 WD domain, G-beta repeat HEAT PF02985.22 KIY73326.1 - 2e-05 24.4 1.6 0.0051 17.0 0.1 3.5 3 0 0 3 3 3 1 HEAT repeat HEAT_2 PF13646.6 KIY73326.1 - 0.014 15.7 1.4 0.04 14.3 0.1 2.6 2 1 0 2 2 2 0 HEAT repeats Cnd1 PF12717.7 KIY73326.1 - 0.023 14.7 0.1 0.058 13.4 0.1 1.6 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 ABC_tran PF00005.27 KIY73327.1 - 1.3e-49 168.3 0.1 4.9e-25 88.6 0.0 2.7 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KIY73327.1 - 1.9e-19 70.6 1.7 0.00016 21.6 0.0 4.3 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 KIY73327.1 - 6.3e-12 45.3 24.9 6.3e-12 45.3 24.9 3.3 4 0 0 4 4 3 1 ABC-2 family transporter protein AAA_23 PF13476.6 KIY73327.1 - 6.4e-08 33.3 4.7 0.0043 17.6 0.4 2.6 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KIY73327.1 - 2.2e-06 27.7 0.1 0.017 15.0 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 KIY73327.1 - 8e-06 25.5 0.7 0.031 14.0 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF4162 PF13732.6 KIY73327.1 - 1e-05 26.2 1.0 0.084 13.6 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4162) AAA_15 PF13175.6 KIY73327.1 - 0.00024 21.0 0.2 0.71 9.5 0.1 3.3 3 0 0 3 3 3 1 AAA ATPase domain AAA_30 PF13604.6 KIY73327.1 - 0.0011 18.8 0.6 0.31 10.7 0.0 3.3 2 1 1 3 3 3 1 AAA domain AAA_27 PF13514.6 KIY73327.1 - 0.0014 18.2 0.3 0.59 9.7 0.1 2.4 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.19 KIY73327.1 - 0.0025 17.3 5.1 7.2 6.0 0.4 3.9 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KIY73327.1 - 0.0028 18.1 0.0 3.7 7.9 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain Rad17 PF03215.15 KIY73327.1 - 0.035 14.0 0.0 5.1 7.0 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain T2SSE PF00437.20 KIY73327.1 - 0.043 12.9 0.2 2.7 7.0 0.0 2.6 2 0 0 2 2 2 0 Type II/IV secretion system protein MukB PF04310.12 KIY73327.1 - 0.083 12.7 1.2 4 7.2 0.1 2.4 2 0 0 2 2 2 0 MukB N-terminal AAA_22 PF13401.6 KIY73327.1 - 0.14 12.4 1.6 11 6.3 0.1 3.1 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KIY73327.1 - 0.29 10.4 2.1 10 5.3 0.1 2.7 3 0 0 3 3 3 0 Zeta toxin SRP54 PF00448.22 KIY73327.1 - 0.52 9.9 3.1 2.9 7.5 0.1 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ABC2_membrane PF01061.24 KIY73327.1 - 0.83 9.0 35.6 0.011 15.2 17.5 3.5 3 0 0 3 3 3 0 ABC-2 type transporter Pox_P21 PF05313.12 KIY73327.1 - 5.7 6.5 8.3 4 7.0 5.8 2.0 2 0 0 2 2 2 0 Poxvirus P21 membrane protein Pkinase PF00069.25 KIY73329.1 - 4.4e-48 163.9 0.1 1e-47 162.8 0.1 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY73329.1 - 2e-25 89.5 0.1 3.9e-25 88.6 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIY73329.1 - 0.0092 14.8 0.2 0.014 14.2 0.2 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KIY73329.1 - 0.029 13.7 0.4 0.065 12.6 0.4 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 KIY73329.1 - 0.067 12.2 0.1 0.11 11.4 0.1 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.22 KIY73329.1 - 0.071 12.7 1.0 1.1 8.8 1.0 2.3 1 1 0 1 1 1 0 RIO1 family APH PF01636.23 KIY73329.1 - 0.073 13.0 0.4 0.79 9.6 0.5 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family PRP38_assoc PF12871.7 KIY73330.1 - 4.9 7.8 41.2 15 6.3 41.2 1.7 1 1 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Methyltransf_25 PF13649.6 KIY73333.1 - 1.8e-14 54.2 0.0 3.8e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIY73333.1 - 6e-12 46.1 0.0 1.2e-11 45.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIY73333.1 - 1.3e-09 38.0 0.0 2e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIY73333.1 - 2.4e-09 37.3 0.0 4.2e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIY73333.1 - 1.1e-07 31.4 0.0 2.1e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 KIY73333.1 - 3.4e-05 23.3 0.0 5.5e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_12 PF08242.12 KIY73333.1 - 8.3e-05 23.3 0.0 0.00018 22.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KIY73333.1 - 0.0038 16.5 0.0 0.0062 15.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.6 KIY73333.1 - 0.083 12.9 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.12 KIY73333.1 - 0.17 11.5 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_4 PF02390.17 KIY73333.1 - 0.23 10.9 0.0 15 5.0 0.0 2.3 2 0 0 2 2 2 0 Putative methyltransferase zf-MYND PF01753.18 KIY73334.1 - 5.1e-11 42.5 14.9 5.1e-11 42.5 14.9 2.7 3 0 0 3 3 3 1 MYND finger zf-MYND PF01753.18 KIY73335.1 - 1.8e-09 37.5 18.0 1.8e-09 37.5 18.0 2.3 3 0 0 3 3 3 1 MYND finger Mlp PF03304.13 KIY73335.1 - 0.094 12.9 0.4 0.22 11.7 0.4 1.6 1 0 0 1 1 1 0 Mlp lipoprotein family TFIID-18kDa PF02269.16 KIY73335.1 - 0.13 12.3 0.0 0.31 11.1 0.0 1.6 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit zf-HIT PF04438.16 KIY73335.1 - 3.5 7.6 12.8 0.72 9.8 8.7 2.0 2 0 0 2 2 2 0 HIT zinc finger CPSase_L_D2 PF02786.17 KIY73336.1 - 6.1e-72 241.5 0.0 1.1e-71 240.7 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KIY73336.1 - 9.1e-48 161.4 0.1 8.9e-47 158.2 0.0 2.4 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KIY73336.1 - 1.7e-30 105.3 0.0 3.2e-30 104.4 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 KIY73336.1 - 3.1e-16 59.0 4.3 7.5e-16 57.7 4.3 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 KIY73336.1 - 3.1e-06 26.9 1.2 0.00011 21.9 0.1 2.6 1 1 1 2 2 2 1 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 KIY73336.1 - 2.6e-05 23.8 0.0 6.1e-05 22.6 0.0 1.5 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KIY73336.1 - 3e-05 23.6 0.0 9.2e-05 22.1 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain RnfC_N PF13375.6 KIY73336.1 - 0.012 15.6 0.5 0.26 11.3 0.2 2.7 3 0 0 3 3 3 0 RnfC Barrel sandwich hybrid domain NQRA PF05896.11 KIY73336.1 - 0.023 14.2 0.5 0.042 13.3 0.5 1.3 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) Fic PF02661.18 KIY73336.1 - 0.029 15.3 0.0 0.094 13.6 0.0 1.9 1 0 0 1 1 1 0 Fic/DOC family HlyD_3 PF13437.6 KIY73336.1 - 0.041 14.6 0.5 8.2 7.2 0.1 2.5 2 0 0 2 2 2 0 HlyD family secretion protein HlyD_D23 PF16576.5 KIY73336.1 - 0.085 12.1 1.0 4.2 6.5 0.1 2.3 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion Ribosomal_S15 PF00312.22 KIY73337.1 - 1.1e-20 73.6 2.8 2e-20 72.8 2.8 1.4 1 0 0 1 1 1 1 Ribosomal protein S15 RhoGEF PF00621.20 KIY73338.1 - 4.8e-10 40.0 0.0 1.5e-09 38.3 0.0 1.8 1 1 0 1 1 1 1 RhoGEF domain zf-CSL PF05207.13 KIY73339.1 - 1.4e-14 53.5 0.6 1.8e-14 53.2 0.6 1.2 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.31 KIY73339.1 - 1.7e-06 28.1 0.0 2.4e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 DnaJ domain zinc_ribbon_4 PF13717.6 KIY73339.1 - 0.00036 20.4 0.5 0.00058 19.7 0.5 1.3 1 0 0 1 1 1 1 zinc-ribbon domain Amnionless PF14828.6 KIY73340.1 - 0.045 12.6 0.0 0.059 12.2 0.0 1.1 1 0 0 1 1 1 0 Amnionless TMEM51 PF15345.6 KIY73340.1 - 0.054 13.3 1.0 0.11 12.3 0.1 1.7 1 1 0 2 2 2 0 Transmembrane protein 51 vMSA PF00695.19 KIY73341.1 - 0.068 12.3 0.0 0.085 11.9 0.0 1.2 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus PADR1 PF08063.12 KIY73341.1 - 0.082 12.7 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 PADR1 (NUC008) domain APH PF01636.23 KIY73342.1 - 1e-08 35.4 1.8 7.3e-08 32.6 1.7 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KIY73342.1 - 0.0001 22.0 0.0 0.0002 21.0 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 KIY73342.1 - 0.013 15.1 0.0 0.056 13.0 0.0 1.8 2 0 0 2 2 2 0 RIO1 family Kdo PF06293.14 KIY73342.1 - 0.037 13.4 0.1 0.22 10.8 0.1 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family RNA_pol_Rpb2_2 PF04561.14 KIY73342.1 - 0.13 11.9 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 2 Pkinase PF00069.25 KIY73342.1 - 0.21 10.9 0.0 0.31 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain SUI1 PF01253.22 KIY73343.1 - 3.4e-18 65.9 0.0 7.5e-18 64.8 0.0 1.6 1 0 0 1 1 1 1 Translation initiation factor SUI1 Pre-PUA PF17832.1 KIY73343.1 - 8.9e-13 48.7 0.0 3.6e-12 46.8 0.0 2.1 2 0 0 2 2 2 1 Pre-PUA-like domain PUA PF01472.20 KIY73343.1 - 3.1e-05 23.9 0.1 6.6e-05 22.8 0.1 1.5 1 0 0 1 1 1 1 PUA domain SWIB PF02201.18 KIY73343.1 - 3.1e-05 23.8 0.0 6.5e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 SWIB/MDM2 domain Abhydrolase_1 PF00561.20 KIY73344.1 - 2.2e-19 70.1 0.0 3.8e-15 56.2 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 KIY73344.1 - 1.2e-14 54.3 0.0 2.1e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Pyr_redox_2 PF07992.14 KIY73345.1 - 9.4e-11 41.5 0.0 3.2e-08 33.2 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KIY73345.1 - 5.9e-08 32.2 0.1 4.3e-05 22.8 0.0 3.2 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.19 KIY73345.1 - 3e-07 29.2 0.1 4.4e-06 25.4 0.1 2.1 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.6 KIY73345.1 - 1.8e-05 24.8 0.0 0.0017 18.4 0.1 3.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KIY73345.1 - 6.4e-05 23.1 0.0 6.4e-05 23.1 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KIY73345.1 - 0.00016 21.4 0.7 0.00092 18.9 0.0 2.4 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KIY73345.1 - 0.00038 19.8 2.9 0.052 12.8 0.2 3.6 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 KIY73345.1 - 0.004 17.0 0.1 0.008 16.1 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.17 KIY73345.1 - 0.019 14.2 0.3 0.47 9.7 0.1 2.7 3 0 0 3 3 3 0 Thi4 family Pyr_redox PF00070.27 KIY73345.1 - 0.045 14.3 4.6 0.48 11.0 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KIY73345.1 - 0.047 13.0 0.9 0.13 11.5 0.0 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 KIY73345.1 - 0.24 10.0 3.3 0.23 10.1 0.2 2.2 3 0 0 3 3 3 0 HI0933-like protein MTS_N PF08468.11 KIY73345.1 - 0.29 11.2 0.4 12 5.9 0.1 2.3 2 0 0 2 2 2 0 Methyltransferase small domain N-terminal FAD_binding_2 PF00890.24 KIY73345.1 - 1.6 7.7 6.6 0.14 11.2 0.3 2.3 3 0 0 3 3 3 0 FAD binding domain G-alpha PF00503.20 KIY73346.1 - 3e-118 395.0 0.0 3.6e-118 394.8 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KIY73346.1 - 8.2e-13 48.2 0.1 1.4e-09 37.6 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family TniB PF05621.11 KIY73346.1 - 0.00011 21.7 0.1 0.00019 20.9 0.1 1.3 1 0 0 1 1 1 1 Bacterial TniB protein Roc PF08477.13 KIY73346.1 - 0.0027 17.9 0.0 2 8.7 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 KIY73346.1 - 0.0073 16.0 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 KIY73346.1 - 0.023 15.1 0.1 0.051 14.0 0.1 1.7 1 0 0 1 1 1 0 AAA ATPase domain FtsK_SpoIIIE PF01580.18 KIY73346.1 - 0.042 13.2 0.0 0.084 12.2 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family MCM PF00493.23 KIY73346.1 - 0.062 12.4 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 MCM P-loop domain GTP_EFTU PF00009.27 KIY73346.1 - 0.074 12.6 0.0 2 7.9 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_24 PF13479.6 KIY73346.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KIY73346.1 - 0.15 12.3 0.0 0.38 11.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF3313 PF11769.8 KIY73347.1 - 0.23 11.3 0.0 0.38 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3313) Peptidase_C12 PF01088.21 KIY73348.1 - 3.7e-53 180.4 0.0 4.2e-53 180.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Proteasome PF00227.26 KIY73349.1 - 1e-53 181.7 0.1 1.3e-53 181.3 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KIY73349.1 - 7e-14 51.2 0.0 1.3e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Ribonuc_L-PSP PF01042.21 KIY73350.1 - 2.2e-39 134.2 0.0 2.5e-39 134.0 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Dor1 PF04124.12 KIY73351.1 - 4.3e-45 153.9 0.5 1.3e-44 152.3 0.5 1.8 1 1 0 1 1 1 1 Dor1-like family Sec5 PF15469.6 KIY73351.1 - 0.0062 16.4 0.0 0.016 15.0 0.0 1.7 1 1 0 1 1 1 1 Exocyst complex component Sec5 Vps51 PF08700.11 KIY73351.1 - 0.11 12.6 0.1 0.35 11.0 0.1 1.9 1 0 0 1 1 1 0 Vps51/Vps67 NPCBM_assoc PF10633.9 KIY73351.1 - 0.12 12.6 0.1 0.27 11.5 0.1 1.5 1 0 0 1 1 1 0 NPCBM-associated, NEW3 domain of alpha-galactosidase ubiquitin PF00240.23 KIY73352.1 - 5.1e-06 26.2 0.2 5.8e-05 22.8 0.2 2.0 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 KIY73352.1 - 3.6e-05 24.1 0.1 0.00024 21.5 0.1 1.9 1 1 0 1 1 1 1 Ubiquitin-like domain PI3K_rbd PF00794.18 KIY73352.1 - 0.062 13.5 0.0 0.066 13.4 0.0 1.1 1 0 0 1 1 1 0 PI3-kinase family, ras-binding domain EloA-BP1 PF15870.5 KIY73353.1 - 0.063 13.5 3.9 0.16 12.2 0.0 2.2 2 0 0 2 2 2 0 ElonginA binding-protein 1 zf-HIT PF04438.16 KIY73354.1 - 1.4e-07 31.2 12.9 2e-07 30.7 12.9 1.2 1 0 0 1 1 1 1 HIT zinc finger Copper-fist PF00649.18 KIY73354.1 - 0.66 9.5 4.7 5.8 6.5 0.9 2.5 2 0 0 2 2 2 0 Copper fist DNA binding domain zf-MYND PF01753.18 KIY73354.1 - 1.5 9.0 12.9 2.4 8.3 12.9 1.4 1 0 0 1 1 1 0 MYND finger Glyco_hydro_18 PF00704.28 KIY73355.1 - 5.3e-24 85.5 6.3 1.5e-23 84.0 6.3 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_5_12 PF02839.14 KIY73355.1 - 2.9e-05 24.4 4.8 0.00017 22.0 4.8 2.5 1 0 0 1 1 1 1 Carbohydrate binding domain F-box-like PF12937.7 KIY73358.1 - 3e-07 30.2 0.7 6.6e-07 29.1 0.7 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY73358.1 - 0.0022 17.8 0.7 0.0078 16.1 0.3 2.3 2 0 0 2 2 2 1 F-box domain Cyclin_C PF02984.19 KIY73358.1 - 0.045 13.8 0.3 0.57 10.3 0.1 2.3 2 0 0 2 2 2 0 Cyclin, C-terminal domain Sel1 PF08238.12 KIY73360.1 - 2e-47 158.6 19.3 4.3e-08 33.6 0.2 8.3 8 0 0 8 8 8 7 Sel1 repeat IBN_N PF03810.19 KIY73361.1 - 8e-12 44.9 0.1 3e-10 39.9 0.0 3.4 4 0 0 4 4 4 1 Importin-beta N-terminal domain DUF3361 PF11841.8 KIY73361.1 - 3.1e-05 24.0 0.1 0.00014 21.8 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3361) Cse1 PF08506.10 KIY73361.1 - 0.00029 19.8 0.0 0.00063 18.7 0.0 1.5 1 0 0 1 1 1 1 Cse1 CAS_CSE1 PF03378.15 KIY73361.1 - 0.0011 17.5 0.1 0.03 12.8 0.0 2.7 3 0 0 3 3 3 1 CAS/CSE protein, C-terminus HEAT_2 PF13646.6 KIY73361.1 - 0.0053 17.1 0.3 1.9 8.9 0.0 4.4 3 2 2 5 5 5 1 HEAT repeats ParcG PF10274.9 KIY73361.1 - 0.011 15.9 0.2 8.6 6.4 0.0 4.1 5 0 0 5 5 5 0 Parkin co-regulated protein TetR_C_32 PF09209.11 KIY73361.1 - 0.038 14.0 0.1 0.21 11.6 0.0 2.3 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain HEAT PF02985.22 KIY73361.1 - 0.039 14.2 0.1 15 6.2 0.1 5.0 5 0 0 5 5 5 0 HEAT repeat DUF3385 PF11865.8 KIY73361.1 - 0.097 12.6 1.0 28 4.6 0.0 4.0 4 1 0 4 4 4 0 Domain of unknown function (DUF3385) ADH_zinc_N PF00107.26 KIY73362.1 - 4.5e-21 75.2 0.0 8.7e-21 74.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KIY73362.1 - 4.2e-18 65.2 0.0 7.6e-18 64.4 0.0 1.3 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 KIY73362.1 - 1.9e-07 32.2 0.0 3.2e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF2855 PF11017.8 KIY73362.1 - 0.01 15.6 0.0 0.027 14.3 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2855) Pkinase PF00069.25 KIY73363.1 - 9.3e-45 153.0 0.0 7e-44 150.2 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY73363.1 - 1.1e-23 83.9 0.0 8e-23 81.0 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KIY73363.1 - 1.2e-06 28.6 0.0 2.1e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KIY73363.1 - 0.0073 15.4 0.1 0.014 14.5 0.1 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Pkinase_fungal PF17667.1 KIY73363.1 - 0.016 14.0 0.0 0.024 13.4 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 KIY73363.1 - 0.038 13.3 0.0 0.056 12.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like MukB_hinge PF16330.5 KIY73364.1 - 0.14 11.9 0.0 0.48 10.1 0.0 1.8 2 0 0 2 2 2 0 MukB hinge domain HhH-GPD PF00730.25 KIY73366.1 - 2.2e-17 63.5 0.0 4.5e-17 62.5 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.6 KIY73366.1 - 1.2e-08 34.9 0.0 1.7e-06 27.9 0.0 2.5 1 1 0 1 1 1 1 NUDIX domain HHH PF00633.23 KIY73366.1 - 5.7e-05 22.8 0.1 0.00021 21.0 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.9 KIY73366.1 - 0.59 10.6 4.6 1.4 9.3 4.6 1.7 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III Inositol_P PF00459.25 KIY73367.1 - 3.1e-61 207.3 0.0 3.4e-61 207.1 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Peripla_BP_2 PF01497.18 KIY73367.1 - 0.099 12.2 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein Pro_isomerase PF00160.21 KIY73368.1 - 5.9e-47 159.9 0.3 6.8e-47 159.7 0.3 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD F-box-like PF12937.7 KIY73369.1 - 0.00088 19.1 2.8 0.0013 18.6 0.2 2.6 2 1 0 2 2 2 1 F-box-like Exo84_C PF16528.5 KIY73370.1 - 3.8e-33 115.0 1.6 7.4e-33 114.1 0.3 2.2 2 1 0 2 2 2 1 Exocyst component 84 C-terminal Vps51 PF08700.11 KIY73370.1 - 6.9e-17 61.3 3.1 1.6e-16 60.1 3.1 1.6 1 0 0 1 1 1 1 Vps51/Vps67 COG2 PF06148.11 KIY73370.1 - 3.7e-06 27.1 1.2 9.4e-06 25.8 1.2 1.6 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Sec3-PIP2_bind PF15277.6 KIY73370.1 - 0.0032 17.5 0.0 0.0074 16.4 0.0 1.6 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Stk19 PF10494.9 KIY73370.1 - 0.094 12.4 0.0 0.3 10.7 0.0 1.9 1 0 0 1 1 1 0 Serine-threonine protein kinase 19 COMPASS-Shg1 PF05205.12 KIY73370.1 - 0.19 12.4 2.4 5.6 7.7 0.6 2.6 2 0 0 2 2 2 0 COMPASS (Complex proteins associated with Set1p) component shg1 Exonuc_VII_S PF02609.16 KIY73370.1 - 0.42 10.7 2.6 25 5.0 0.0 2.5 2 0 0 2 2 2 0 Exonuclease VII small subunit PAN_3 PF08277.12 KIY73371.1 - 1.4e-14 53.6 29.8 0.0018 18.0 2.3 5.8 5 0 0 5 5 5 5 PAN-like domain PAN_2 PF08276.11 KIY73371.1 - 5.5e-05 23.2 19.1 0.17 12.0 0.2 5.5 5 0 0 5 5 5 3 PAN-like domain PAN_4 PF14295.6 KIY73371.1 - 0.0023 17.8 32.6 0.0026 17.6 0.9 5.4 6 0 0 6 6 6 3 PAN domain MANEC PF07502.14 KIY73371.1 - 0.015 15.5 17.3 4.8 7.5 0.1 6.4 7 0 0 7 7 7 0 MANEC domain Laminin_G_2 PF02210.24 KIY73371.1 - 0.18 12.4 0.7 16 6.1 0.0 3.7 4 1 0 4 4 4 0 Laminin G domain DUF5122 PF17164.4 KIY73371.1 - 0.19 12.0 2.2 1.2 9.5 0.3 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF5122) beta-propeller TMEM125 PF15109.6 KIY73371.1 - 0.2 12.0 2.8 8.5 6.8 0.1 2.8 2 0 0 2 2 2 0 TMEM125 protein family DUF515 PF04415.12 KIY73371.1 - 0.63 8.4 17.9 0.72 8.2 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF515) WSC PF01822.19 KIY73371.1 - 8.8 6.6 35.5 0.081 13.1 0.6 5.7 7 0 0 7 7 7 0 WSC domain Fip1 PF05182.13 KIY73373.1 - 6.8e-21 73.5 0.5 1.3e-20 72.6 0.5 1.5 1 0 0 1 1 1 1 Fip1 motif Myc_N PF01056.18 KIY73373.1 - 0.037 13.9 5.3 0.059 13.3 5.3 1.3 1 0 0 1 1 1 0 Myc amino-terminal region Ribosomal_60s PF00428.19 KIY73373.1 - 0.57 10.8 16.6 0.049 14.2 9.2 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein Lin-8 PF03353.15 KIY73373.1 - 0.92 9.0 4.9 1.4 8.5 4.9 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Nop14 PF04147.12 KIY73373.1 - 2 6.5 7.8 2.7 6.1 7.8 1.0 1 0 0 1 1 1 0 Nop14-like family HGTP_anticodon2 PF12745.7 KIY73373.1 - 2.3 7.6 5.2 3.4 7.1 5.2 1.1 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs DNA_pol_phi PF04931.13 KIY73373.1 - 3.8 5.5 10.4 5 5.1 10.4 1.0 1 0 0 1 1 1 0 DNA polymerase phi Astro_capsid_p PF12226.8 KIY73373.1 - 6 5.9 7.6 9.1 5.3 7.6 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein CDC45 PF02724.14 KIY73373.1 - 6.3 5.0 5.7 8.9 4.5 5.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Rotamase PF00639.21 KIY73374.1 - 4.7e-21 75.6 0.0 5.8e-21 75.3 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 KIY73374.1 - 1.3e-19 70.9 0.0 1.6e-19 70.5 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 KIY73374.1 - 1.6e-05 24.9 2.6 3.3e-05 23.9 1.3 2.0 2 0 0 2 2 2 1 WW domain Rotamase_2 PF13145.6 KIY73374.1 - 0.0026 18.6 0.0 0.0038 18.1 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain MOSC PF03473.17 KIY73375.1 - 8.3e-23 80.8 0.0 1.3e-22 80.2 0.0 1.3 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 KIY73375.1 - 9.9e-20 70.6 0.0 1.5e-19 70.1 0.0 1.3 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain UCH PF00443.29 KIY73376.1 - 2.7e-53 181.1 0.0 3.6e-53 180.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KIY73376.1 - 1.5e-28 100.4 0.5 2e-20 73.7 0.1 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 KIY73376.1 - 0.31 10.5 4.2 0.26 10.7 1.7 2.1 3 0 0 3 3 3 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase zf-RVT PF13966.6 KIY73377.1 - 1.4e-05 25.7 3.2 1.5e-05 25.6 1.2 2.1 2 1 0 2 2 2 1 zinc-binding in reverse transcriptase NTase_sub_bind PF08780.11 KIY73377.1 - 0.084 12.8 0.6 6.4 6.7 0.0 2.2 2 0 0 2 2 2 0 Nucleotidyltransferase substrate binding protein like RVT_1 PF00078.27 KIY73378.1 - 4e-06 26.5 0.0 1.3e-05 24.8 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 KIY73379.1 - 0.0082 15.7 0.1 0.044 13.3 0.1 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family F-box-like PF12937.7 KIY73381.1 - 0.034 14.1 0.3 0.034 14.1 0.3 3.2 4 0 0 4 4 4 0 F-box-like F-box PF00646.33 KIY73381.1 - 0.069 13.0 0.1 0.22 11.4 0.1 2.0 1 0 0 1 1 1 0 F-box domain DUF4851 PF16143.5 KIY73381.1 - 0.15 11.5 0.6 0.24 10.8 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4851) F-box-like PF12937.7 KIY73382.1 - 0.0032 17.3 0.7 0.0059 16.5 0.7 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY73382.1 - 0.011 15.6 1.0 0.022 14.6 1.0 1.4 1 0 0 1 1 1 0 F-box domain SPO22 PF08631.10 KIY73384.1 - 2.4e-47 161.7 9.3 2.5e-47 161.7 1.4 3.5 4 0 0 4 4 4 1 Meiosis protein SPO22/ZIP4 like TPR_19 PF14559.6 KIY73384.1 - 2.7e-06 27.8 0.4 0.0017 18.8 0.0 3.6 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KIY73384.1 - 1.6e-05 25.1 2.4 0.019 15.2 0.2 3.9 4 0 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 KIY73384.1 - 0.049 13.8 0.8 15 6.1 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 KIY73384.1 - 0.27 11.4 1.3 16 5.8 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 KIY73384.1 - 0.33 11.3 14.6 4 7.8 0.2 6.1 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_2 PF07719.17 KIY73384.1 - 1.8 8.9 10.6 0.96 9.7 0.4 4.5 4 1 1 5 5 5 0 Tetratricopeptide repeat Glyco_hydro_5_C PF18564.1 KIY73386.1 - 9.5e-24 83.8 0.0 2.1e-23 82.7 0.0 1.6 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Cellulase PF00150.18 KIY73386.1 - 1.1e-13 51.3 0.0 3.3e-09 36.6 0.0 2.5 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) UCH PF00443.29 KIY73387.1 - 2.8e-43 148.3 0.0 5.7e-43 147.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.6 KIY73387.1 - 3.8e-19 68.4 0.2 3.1e-14 52.6 0.1 2.7 2 0 0 2 2 2 2 A repeated domain in UCH-protein UCH_1 PF13423.6 KIY73387.1 - 1.6e-10 41.1 1.7 7.4e-05 22.5 0.3 3.2 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase DivIC PF04977.15 KIY73387.1 - 0.42 10.4 5.8 2.6 7.9 2.3 2.6 2 0 0 2 2 2 0 Septum formation initiator NPV_P10 PF05531.12 KIY73387.1 - 0.86 10.1 2.9 32 5.1 1.0 2.8 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Glyco_hyd_65N_2 PF14498.6 KIY73388.1 - 0.012 15.4 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain Pkinase PF00069.25 KIY73390.1 - 2.5e-67 227.0 0.0 3e-67 226.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY73390.1 - 1e-31 110.2 0.0 1.2e-31 109.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KIY73390.1 - 9.2e-06 24.8 0.0 1.3e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KIY73390.1 - 0.00062 19.2 0.1 0.0018 17.6 0.1 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KIY73390.1 - 0.0011 19.0 0.0 0.0023 17.9 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 KIY73390.1 - 0.016 14.8 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 KIY73390.1 - 0.018 14.4 0.0 0.048 13.0 0.0 1.7 1 1 1 2 2 2 0 Kinase-like RIO1 PF01163.22 KIY73390.1 - 0.046 13.3 0.0 0.07 12.7 0.0 1.3 1 0 0 1 1 1 0 RIO1 family NAD_binding_1 PF00175.21 KIY73391.1 - 1.7e-25 89.8 0.0 3e-25 89.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KIY73391.1 - 8.3e-20 71.0 0.0 1.7e-19 70.0 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KIY73391.1 - 8.3e-07 29.3 0.0 0.00029 21.0 0.0 2.4 2 0 0 2 2 2 2 Ferric reductase NAD binding domain DUF5336 PF17270.2 KIY73391.1 - 0.07 12.8 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5336) ADH_zinc_N PF00107.26 KIY73392.1 - 3.4e-28 98.2 0.0 5.4e-28 97.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KIY73392.1 - 9.8e-20 72.0 0.0 2e-19 70.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIY73392.1 - 0.0036 17.2 0.0 0.0098 15.8 0.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 KIY73392.1 - 0.0045 17.2 0.1 0.0093 16.2 0.1 1.5 1 0 0 1 1 1 1 TrkA-N domain SIS_2 PF13580.6 KIY73392.1 - 0.012 15.7 0.0 0.02 14.9 0.0 1.4 1 0 0 1 1 1 0 SIS domain PALP PF00291.25 KIY73392.1 - 0.025 14.0 0.1 0.036 13.5 0.1 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme YAcAr PF10686.9 KIY73392.1 - 0.032 14.2 0.1 0.067 13.1 0.1 1.5 1 0 0 1 1 1 0 YspA, cpYpsA-related SLOG family ADH_zinc_N PF00107.26 KIY73393.1 - 7.3e-27 93.9 0.0 1.5e-26 92.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KIY73393.1 - 4.8e-21 76.2 0.0 1.1e-20 75.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KIY73393.1 - 5.9e-05 22.9 0.0 0.00015 21.6 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 KIY73393.1 - 0.0091 16.2 0.0 0.036 14.3 0.0 2.0 2 0 0 2 2 2 1 TrkA-N domain DUF2855 PF11017.8 KIY73393.1 - 0.013 15.3 0.1 0.018 14.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2855) PALP PF00291.25 KIY73393.1 - 0.02 14.3 0.1 0.03 13.7 0.1 1.3 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme SIS_2 PF13580.6 KIY73393.1 - 0.061 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 SIS domain Ribonuc_red_sm PF00268.21 KIY73394.1 - 2.9e-118 394.4 0.0 3.5e-118 394.1 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain DUF4744 PF15918.5 KIY73394.1 - 0.054 14.3 0.3 0.18 12.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4744) CAF1C_H4-bd PF12265.8 KIY73395.1 - 5.6e-29 100.2 0.9 1e-27 96.1 0.5 2.7 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 KIY73395.1 - 9.3e-22 76.9 11.7 2.1e-06 28.3 0.1 5.8 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY73395.1 - 0.00021 21.5 0.2 0.094 13.0 0.0 3.6 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 KIY73395.1 - 0.058 11.7 0.0 0.11 10.8 0.0 1.3 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz DUF2431 PF10354.9 KIY73396.1 - 7.8e-56 188.9 0.0 1.2e-55 188.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) F-box-like PF12937.7 KIY73398.1 - 3.9e-07 29.9 0.2 8.5e-07 28.8 0.2 1.6 1 0 0 1 1 1 1 F-box-like ATP-synt_E PF05680.12 KIY73399.1 - 2.5e-19 69.4 0.4 2.7e-19 69.3 0.4 1.1 1 0 0 1 1 1 1 ATP synthase E chain LdpA_C PF12617.8 KIY73399.1 - 0.017 14.7 0.1 0.02 14.5 0.1 1.1 1 0 0 1 1 1 0 Iron-Sulfur binding protein C terminal Acetyltransf_2 PF00797.17 KIY73400.1 - 6.3e-25 88.4 0.0 1e-24 87.7 0.0 1.3 1 0 0 1 1 1 1 N-acetyltransferase MurB_C PF02873.16 KIY73400.1 - 0.15 12.2 0.0 0.91 9.6 0.0 2.0 2 0 0 2 2 2 0 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain Acetyltransf_2 PF00797.17 KIY73402.1 - 5.3e-29 101.7 0.0 1.2e-28 100.6 0.0 1.5 2 0 0 2 2 2 1 N-acetyltransferase Ank_2 PF12796.7 KIY73404.1 - 5.5e-37 126.2 0.0 7.9e-14 52.0 0.0 4.7 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KIY73404.1 - 5e-31 103.3 0.7 0.00024 21.3 0.0 8.0 9 0 0 9 9 9 6 Ankyrin repeat Ank_4 PF13637.6 KIY73404.1 - 4.3e-28 97.3 0.6 1.6e-05 25.3 0.0 6.5 2 2 5 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.30 KIY73404.1 - 8.6e-26 89.2 0.3 0.00093 19.5 0.0 7.0 6 1 1 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 KIY73404.1 - 4.8e-22 77.7 1.6 2.1e-08 34.2 0.0 6.3 6 1 2 8 8 8 4 Ankyrin repeats (many copies) DUF1843 PF08898.10 KIY73404.1 - 0.13 12.8 0.0 1.7 9.2 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) BSP PF04450.12 KIY73405.1 - 8.8e-55 185.7 0.0 1e-54 185.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase of plants and bacteria PhyH PF05721.13 KIY73406.1 - 4.5e-11 43.4 0.0 6.5e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF523 PF04463.12 KIY73407.1 - 0.11 12.6 0.1 0.16 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF523) NLRC4_HD PF17889.1 KIY73409.1 - 0.16 12.3 0.9 0.23 11.8 0.9 1.2 1 0 0 1 1 1 0 NLRC4 helical domain DUF1479 PF07350.12 KIY73410.1 - 1.9e-143 478.2 0.0 2.2e-143 478.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) ING PF12998.7 KIY73411.1 - 1.4e-12 48.1 0.0 2e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 KIY73411.1 - 1.3e-06 28.2 4.3 2.1e-06 27.5 4.3 1.3 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 KIY73411.1 - 0.063 13.5 0.2 0.13 12.6 0.2 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain Prefoldin_2 PF01920.20 KIY73412.1 - 0.0061 16.5 1.8 0.013 15.4 1.8 1.6 1 0 0 1 1 1 1 Prefoldin subunit Tropomyosin PF00261.20 KIY73412.1 - 0.0097 15.3 0.6 0.019 14.4 0.6 1.4 1 0 0 1 1 1 1 Tropomyosin XhlA PF10779.9 KIY73412.1 - 0.01 16.0 0.1 0.022 15.0 0.1 1.5 1 0 0 1 1 1 0 Haemolysin XhlA Spc7 PF08317.11 KIY73412.1 - 0.012 14.6 1.4 0.023 13.6 1.4 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Filament PF00038.21 KIY73412.1 - 0.016 14.8 1.8 0.028 14.0 1.8 1.3 1 0 0 1 1 1 0 Intermediate filament protein Fib_alpha PF08702.10 KIY73412.1 - 0.023 14.9 1.0 0.023 14.9 1.0 2.6 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Csm1_N PF18504.1 KIY73412.1 - 0.064 13.6 0.9 0.2 12.0 0.9 1.9 1 0 0 1 1 1 0 Csm1 N-terminal domain Prefoldin PF02996.17 KIY73412.1 - 0.083 12.8 3.1 0.2 11.6 3.1 1.6 1 0 0 1 1 1 0 Prefoldin subunit CENP-F_leu_zip PF10473.9 KIY73412.1 - 0.093 12.8 0.3 0.093 12.8 0.3 1.9 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMPIT PF07851.13 KIY73412.1 - 0.13 11.5 0.1 0.85 8.8 0.3 1.9 2 0 0 2 2 2 0 TMPIT-like protein ADIP PF11559.8 KIY73412.1 - 0.2 11.7 5.5 0.053 13.6 1.9 1.9 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding ABC_tran_CTD PF16326.5 KIY73412.1 - 0.23 11.7 2.3 0.53 10.6 2.3 1.6 1 0 0 1 1 1 0 ABC transporter C-terminal domain Spc24 PF08286.11 KIY73412.1 - 0.45 10.8 4.9 3.6 7.9 0.3 2.7 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 Sugarporin_N PF11471.8 KIY73412.1 - 0.59 10.1 5.8 2.4 8.2 2.3 2.7 1 1 1 2 2 2 0 Maltoporin periplasmic N-terminal extension Amino_oxidase PF01593.24 KIY73413.1 - 2e-35 123.0 0.0 2.8e-35 122.5 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KIY73413.1 - 0.0074 16.5 0.0 0.027 14.7 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KIY73414.1 - 1.2e-29 104.0 0.0 1.4e-29 103.8 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KIY73414.1 - 1.5e-09 37.5 0.0 5.8e-09 35.5 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KIY73414.1 - 6.8e-07 28.3 0.0 1.3e-06 27.4 0.0 1.4 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 KIY73414.1 - 2.3e-06 27.0 0.0 3.7e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 KIY73414.1 - 9.8e-06 25.2 0.1 1.9e-05 24.2 0.1 1.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KIY73414.1 - 0.00036 19.9 0.1 0.00057 19.2 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KIY73414.1 - 0.00049 19.5 0.0 0.0013 18.1 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KIY73414.1 - 0.0005 20.3 0.0 0.0014 18.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KIY73414.1 - 0.00076 18.8 0.0 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIY73414.1 - 0.0046 17.5 0.0 0.017 15.6 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KIY73414.1 - 0.006 17.0 0.0 0.012 16.0 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Lycopene_cycl PF05834.12 KIY73414.1 - 0.021 13.9 0.1 0.035 13.2 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Trp_halogenase PF04820.14 KIY73414.1 - 0.052 12.4 0.0 0.076 11.8 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase GIDA PF01134.22 KIY73414.1 - 0.064 12.3 0.0 0.094 11.8 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A efThoc1 PF11957.8 KIY73416.1 - 2.4e-87 293.7 2.6 2.7e-83 280.3 0.1 2.1 1 1 0 2 2 2 2 THO complex subunit 1 transcription elongation factor Lipocalin_2 PF08212.12 KIY73416.1 - 0.43 10.5 3.2 1.8 8.5 0.0 2.6 2 0 0 2 2 2 0 Lipocalin-like domain DUF3138 PF11336.8 KIY73416.1 - 3.6 6.1 10.0 5.4 5.5 10.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF4746 PF15928.5 KIY73416.1 - 8.2 5.8 15.4 3.5 7.0 8.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) MDM10 PF12519.8 KIY73417.1 - 2.3e-95 320.2 0.0 2.8e-86 290.2 0.0 2.0 1 1 1 2 2 2 2 Mitochondrial distribution and morphology protein 10 Pet100 PF09803.9 KIY73418.1 - 8.8e-26 90.2 0.2 1e-25 90.1 0.2 1.0 1 0 0 1 1 1 1 Pet100 F-box-like PF12937.7 KIY73419.1 - 1e-07 31.7 0.9 2.9e-07 30.3 0.9 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY73419.1 - 0.086 12.8 0.8 1.6 8.7 0.8 2.8 1 1 0 1 1 1 0 F-box domain CLZ PF16526.5 KIY73419.1 - 0.18 12.2 1.6 0.72 10.3 0.5 2.2 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ABC2_membrane PF01061.24 KIY73420.1 - 5.7e-72 241.5 56.3 9.1e-37 126.5 26.8 2.5 3 0 0 3 3 2 2 ABC-2 type transporter ABC_tran PF00005.27 KIY73420.1 - 6.2e-33 114.2 0.0 1.9e-16 60.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KIY73420.1 - 1.8e-22 79.0 1.4 8.3e-16 57.7 0.0 2.9 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.6 KIY73420.1 - 9.8e-11 42.1 0.1 3.4e-10 40.4 0.1 2.0 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_22 PF13401.6 KIY73420.1 - 9e-06 26.0 0.6 0.23 11.7 0.2 3.3 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KIY73420.1 - 0.00015 22.3 1.3 0.098 13.2 0.0 3.3 3 0 0 3 3 3 1 AAA domain cobW PF02492.19 KIY73420.1 - 0.00038 20.1 0.1 0.23 11.0 0.0 2.5 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 KIY73420.1 - 0.00052 20.2 4.0 0.076 13.2 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 KIY73420.1 - 0.00078 19.9 0.4 0.46 10.8 0.3 3.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 KIY73420.1 - 0.0013 18.4 0.5 0.15 11.8 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KIY73420.1 - 0.0054 16.6 0.1 0.039 13.9 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_17 PF13207.6 KIY73420.1 - 0.0055 17.1 0.1 1.3 9.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KIY73420.1 - 0.008 16.0 0.2 1.1 9.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system PDR_assoc PF08370.11 KIY73420.1 - 0.023 14.4 0.0 0.023 14.4 0.0 3.0 3 0 0 3 3 2 0 Plant PDR ABC transporter associated AAA_28 PF13521.6 KIY73420.1 - 0.024 14.9 0.3 0.84 9.9 0.2 2.6 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 KIY73420.1 - 0.031 13.7 0.0 0.74 9.2 0.0 2.8 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 KIY73420.1 - 0.034 13.7 0.0 0.29 10.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KIY73420.1 - 0.12 12.1 0.1 17 5.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain ABC2_membrane_3 PF12698.7 KIY73420.1 - 0.14 11.2 41.1 0.15 11.2 19.4 2.7 2 0 0 2 2 2 0 ABC-2 family transporter protein AAA_30 PF13604.6 KIY73420.1 - 0.49 10.1 4.4 4.7 6.9 0.2 3.1 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.6 KIY73420.1 - 0.69 10.3 4.1 16 5.8 0.0 3.6 3 1 0 3 3 3 0 AAA domain EF-hand_6 PF13405.6 KIY73421.1 - 8.5e-11 40.9 0.2 8.8e-05 22.1 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 KIY73421.1 - 1.2e-08 34.0 1.1 2.3e-05 23.6 0.0 2.8 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 KIY73421.1 - 2.3e-08 34.4 0.7 6.4e-08 32.9 0.3 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 KIY73421.1 - 8.7e-07 28.1 0.5 0.00068 19.0 0.0 2.6 2 0 0 2 2 2 2 EF hand SPARC_Ca_bdg PF10591.9 KIY73421.1 - 0.015 15.6 5.0 1.3 9.4 0.2 2.8 2 1 1 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.6 KIY73421.1 - 0.088 12.7 0.3 8.2 6.4 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain pair Dopey_N PF04118.14 KIY73422.1 - 3.6e-110 367.9 0.1 1.6e-109 365.7 0.0 2.3 2 0 0 2 2 2 1 Dopey, N-terminal Melibiase_2 PF16499.5 KIY73423.1 - 7.8e-59 199.2 1.7 1.2e-58 198.6 1.7 1.3 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 KIY73423.1 - 3.6e-12 46.2 0.0 7.9e-12 45.1 0.0 1.6 1 0 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 KIY73423.1 - 6.6e-07 28.6 0.0 1.1e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Melibiase YL1 PF05764.13 KIY73424.1 - 0.16 12.1 1.4 0.23 11.6 1.4 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Glyco_hydro_18 PF00704.28 KIY73425.1 - 4e-23 82.6 3.3 1.2e-22 81.0 3.2 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_5_12 PF02839.14 KIY73425.1 - 0.038 14.6 2.9 0.038 14.6 2.9 2.6 2 0 0 2 2 2 0 Carbohydrate binding domain adh_short_C2 PF13561.6 KIY73426.1 - 3.2e-54 184.0 0.4 4.3e-54 183.6 0.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIY73426.1 - 9.1e-49 165.6 1.1 1.1e-48 165.3 1.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIY73426.1 - 1.8e-07 31.3 0.4 2.3e-07 30.9 0.4 1.2 1 0 0 1 1 1 1 KR domain Peripla_BP_6 PF13458.6 KIY73426.1 - 0.052 13.2 0.7 0.16 11.6 0.3 1.8 1 1 1 2 2 2 0 Periplasmic binding protein RabGAP-TBC PF00566.18 KIY73428.1 - 1.1e-45 155.9 0.0 1.5e-45 155.5 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain RNase_H PF00075.24 KIY73429.1 - 6.2e-36 123.7 0.0 9.3e-36 123.1 0.0 1.2 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.16 KIY73429.1 - 2.3e-21 75.8 0.7 3.9e-21 75.1 0.7 1.4 1 0 0 1 1 1 1 Caulimovirus viroplasmin RVT_3 PF13456.6 KIY73429.1 - 0.014 15.2 0.0 0.66 9.8 0.0 2.4 2 0 0 2 2 2 0 Reverse transcriptase-like DDE_Tnp_1_4 PF13701.6 KIY73429.1 - 0.12 10.7 0.0 0.16 10.2 0.0 1.1 1 0 0 1 1 1 0 Transposase DDE domain group 1 F-box-like PF12937.7 KIY73431.1 - 1.8e-07 30.9 0.2 3.7e-07 29.9 0.2 1.6 1 0 0 1 1 1 1 F-box-like Arm PF00514.23 KIY73431.1 - 0.045 13.8 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 Armadillo/beta-catenin-like repeat Pkinase_Tyr PF07714.17 KIY73433.1 - 1.1e-34 119.9 0.0 2e-34 119.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KIY73433.1 - 1e-32 113.6 0.0 1.1e-31 110.2 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.23 KIY73433.1 - 0.0018 18.2 0.3 0.39 10.6 0.0 2.8 2 2 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 KIY73433.1 - 0.0052 16.2 0.0 0.017 14.5 0.0 1.8 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KIY73433.1 - 0.015 14.7 0.0 0.034 13.5 0.0 1.5 1 0 0 1 1 1 0 Kinase-like DUF883 PF05957.13 KIY73433.1 - 0.067 13.8 2.0 0.32 11.6 0.0 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) RIO1 PF01163.22 KIY73433.1 - 0.13 11.8 2.3 0.66 9.6 0.0 2.7 3 0 0 3 3 3 0 RIO1 family PHD PF00628.29 KIY73434.1 - 1.7e-07 31.0 7.5 2.7e-07 30.4 7.5 1.3 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 KIY73434.1 - 0.0036 17.5 2.8 0.0051 17.0 2.8 1.3 1 0 0 1 1 1 1 PHD-like zinc-binding domain SPX PF03105.19 KIY73434.1 - 3.8 7.3 5.8 4.5 7.1 5.8 1.0 1 0 0 1 1 1 0 SPX domain DSHCT PF08148.12 KIY73436.1 - 2e-52 177.2 0.4 3.7e-52 176.3 0.4 1.4 1 0 0 1 1 1 1 DSHCT (NUC185) domain Ski2_N PF17911.1 KIY73436.1 - 4.4e-34 117.2 0.1 1.6e-33 115.4 0.0 1.9 2 0 0 2 2 2 1 Ski2 N-terminal region rRNA_proc-arch PF13234.6 KIY73436.1 - 1.7e-23 83.9 0.0 2.7e-23 83.3 0.0 1.3 1 0 0 1 1 1 1 rRNA-processing arch domain DEAD PF00270.29 KIY73436.1 - 3.1e-18 66.1 0.0 5.8e-18 65.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KIY73436.1 - 1.2e-05 25.4 0.1 2e-05 24.6 0.1 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KIY73436.1 - 1.6e-05 25.2 0.0 4.5e-05 23.8 0.0 1.9 1 1 0 1 1 1 1 Helicase conserved C-terminal domain Ras PF00071.22 KIY73437.1 - 4.1e-58 195.6 0.0 4.7e-58 195.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIY73437.1 - 1e-35 122.5 0.0 1.4e-35 122.1 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIY73437.1 - 1.1e-12 47.8 0.0 1.2e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KIY73437.1 - 3.7e-06 27.0 0.0 5.3e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KIY73437.1 - 3.9e-05 23.1 0.0 4.7e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KIY73437.1 - 6.9e-05 22.8 0.0 0.34 10.8 0.1 2.2 1 1 1 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KIY73437.1 - 0.00073 19.1 0.0 0.0013 18.3 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 KIY73437.1 - 0.012 16.0 0.1 0.021 15.2 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain Septin PF00735.18 KIY73437.1 - 0.039 13.2 0.0 0.056 12.7 0.0 1.2 1 0 0 1 1 1 0 Septin G-alpha PF00503.20 KIY73437.1 - 0.18 10.9 0.1 2.7 7.0 0.1 2.0 1 1 1 2 2 2 0 G-protein alpha subunit TniB PF05621.11 KIY73437.1 - 0.18 11.2 0.0 0.37 10.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein RRM_1 PF00076.22 KIY73438.1 - 1.1e-12 47.5 0.0 7e-10 38.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) APH PF01636.23 KIY73439.1 - 3.3e-15 56.7 0.0 1e-14 55.1 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 KIY73439.1 - 3.5e-06 26.1 0.0 0.0052 15.7 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) GBP_C PF02841.14 KIY73440.1 - 2.8 7.2 12.9 5 6.4 12.9 1.3 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain NCBP3 PF10309.9 KIY73441.1 - 5.6e-07 29.3 0.0 9.5e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 RNA_bind PF08675.11 KIY73441.1 - 7.3e-05 22.7 0.0 0.00013 21.9 0.0 1.4 1 0 0 1 1 1 1 RNA binding domain HTH_17 PF12728.7 KIY73443.1 - 0.13 12.4 0.1 2.7 8.3 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain Methyltransf_23 PF13489.6 KIY73444.1 - 4.5e-10 39.6 0.0 6.9e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIY73444.1 - 4.7e-08 33.6 0.0 1.8e-07 31.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIY73444.1 - 5.7e-07 30.2 0.1 2.2e-06 28.3 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIY73444.1 - 9.9e-07 28.7 0.0 2.1e-05 24.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIY73444.1 - 1.6e-05 25.4 0.0 3.8e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KIY73444.1 - 4.1e-05 23.1 0.0 0.00087 18.8 0.0 2.4 2 0 0 2 2 2 1 Putative methyltransferase FtsJ PF01728.19 KIY73444.1 - 0.00057 20.0 0.0 0.00094 19.3 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_2 PF00891.18 KIY73444.1 - 0.0092 15.3 0.0 0.015 14.6 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 KIY73444.1 - 0.04 13.5 0.0 0.079 12.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_29 PF03141.16 KIY73444.1 - 0.17 10.4 0.0 0.37 9.3 0.0 1.4 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase PrmA PF06325.13 KIY73444.1 - 0.24 10.8 0.0 0.37 10.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ist1 PF03398.14 KIY73445.1 - 3.1e-61 206.1 0.7 3.7e-61 205.8 0.7 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Upf2 PF04050.14 KIY73445.1 - 0.3 11.8 4.0 0.22 12.3 0.4 2.3 2 1 0 2 2 2 0 Up-frameshift suppressor 2 RasGEF PF00617.19 KIY73446.1 - 2.9e-39 135.1 0.0 4.8e-39 134.4 0.0 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KIY73446.1 - 2.4e-14 53.4 0.0 4.9e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.28 KIY73446.1 - 2.7e-13 49.3 0.1 5.7e-13 48.2 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KIY73446.1 - 1.2e-10 40.9 0.2 3.6e-10 39.4 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 KIY73446.1 - 7.8e-06 25.7 0.3 1.7e-05 24.6 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain F-box-like PF12937.7 KIY73447.1 - 3.4e-09 36.4 1.3 7e-09 35.4 1.3 1.6 1 0 0 1 1 1 1 F-box-like M16C_assoc PF08367.11 KIY73447.1 - 0.1 11.7 0.5 0.17 11.0 0.5 1.2 1 0 0 1 1 1 0 Peptidase M16C associated F-box-like PF12937.7 KIY73448.1 - 1.2e-07 31.5 1.0 1.2e-07 31.5 1.0 1.9 2 0 0 2 2 2 1 F-box-like DUF3584 PF12128.8 KIY73448.1 - 0.063 10.8 1.0 0.08 10.4 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) SIKE PF05769.11 KIY73450.1 - 7.4e-10 39.0 15.4 1.1e-06 28.7 9.8 2.6 2 1 1 3 3 3 2 SIKE family Cnn_1N PF07989.11 KIY73450.1 - 0.13 12.4 8.3 0.17 12.0 0.8 3.4 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 NYD-SP28_assoc PF14775.6 KIY73450.1 - 0.33 11.1 14.2 1.2 9.3 0.4 3.5 3 0 0 3 3 3 0 Sperm tail C-terminal domain CREPT PF16566.5 KIY73450.1 - 0.68 10.1 8.7 13 6.0 0.2 2.6 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Herpes_BLRF2 PF05812.12 KIY73450.1 - 4.4 7.5 7.4 4.8 7.3 0.1 3.1 2 1 1 3 3 3 0 Herpesvirus BLRF2 protein bZIP_2 PF07716.15 KIY73450.1 - 4.9 7.3 13.8 6 7.0 1.8 3.7 3 0 0 3 3 3 0 Basic region leucine zipper Glyco_hydro_61 PF03443.14 KIY73452.1 - 1e-60 205.2 0.1 1.3e-60 204.8 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 OPT PF03169.15 KIY73454.1 - 6.6e-139 464.4 25.3 7.7e-139 464.1 25.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF3995 PF13160.6 KIY73454.1 - 2.6 8.4 19.3 0.044 14.1 1.2 4.0 5 0 0 5 5 5 0 Protein of unknown function (DUF3995) Cellulase PF00150.18 KIY73455.1 - 3.4e-48 164.5 0.0 4.3e-48 164.2 0.0 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) APH PF01636.23 KIY73458.1 - 5.4e-15 56.0 0.1 1.5e-14 54.6 0.1 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KIY73458.1 - 0.0033 17.0 0.0 0.0053 16.4 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase HmuY PF14064.6 KIY73458.1 - 0.053 13.7 0.1 0.08 13.2 0.1 1.2 1 0 0 1 1 1 0 HmuY protein PufQ PF05398.11 KIY73458.1 - 0.091 12.9 0.2 0.21 11.8 0.2 1.5 1 0 0 1 1 1 0 PufQ cytochrome subunit RIO1 PF01163.22 KIY73458.1 - 0.18 11.4 0.0 4.5 6.8 0.0 2.1 2 0 0 2 2 2 0 RIO1 family Plavaka PF18759.1 KIY73463.1 - 1.7e-113 379.1 0.2 2.4e-113 378.7 0.2 1.2 1 0 0 1 1 1 1 Plavaka transposase zf-C2H2 PF00096.26 KIY73463.1 - 5.3 7.7 6.8 0.34 11.5 0.4 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type Phage_integrase PF00589.22 KIY73464.1 - 6.1e-05 22.9 0.0 0.00012 21.9 0.0 1.4 1 0 0 1 1 1 1 Phage integrase family O-FucT PF10250.9 KIY73465.1 - 4.5e-17 62.8 0.0 6e-17 62.3 0.0 1.2 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Exog_C PF18026.1 KIY73465.1 - 0.082 13.0 0.1 11 6.1 0.0 2.4 2 0 0 2 2 2 0 Endo/exonuclease (EXOG) C-terminal domain TPT PF03151.16 KIY73466.1 - 1.5e-10 40.9 24.2 1.8e-10 40.7 24.2 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family RabGAP-TBC PF00566.18 KIY73468.1 - 1.7e-30 106.3 0.0 2.8e-30 105.6 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SBE2 PF17076.5 KIY73468.1 - 0.53 8.4 1.3 0.69 8.1 1.3 1.1 1 0 0 1 1 1 0 SBE2, cell-wall formation SelB-wing_1 PF09105.10 KIY73468.1 - 1 9.4 2.8 40 4.3 1.1 2.6 2 0 0 2 2 2 0 Elongation factor SelB, winged helix I-set PF07679.16 KIY73469.1 - 0.00053 20.0 0.0 4.9 7.3 0.0 4.2 3 0 0 3 3 3 2 Immunoglobulin I-set domain PBP1_TM PF14812.6 KIY73469.1 - 0.28 11.6 2.8 0.58 10.6 2.8 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal dsrm PF00035.26 KIY73470.1 - 2.7e-09 37.6 0.1 6e-09 36.5 0.1 1.6 1 0 0 1 1 1 1 Double-stranded RNA binding motif CAP_N PF01213.19 KIY73470.1 - 0.85 9.0 6.6 1.2 8.5 6.6 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Thioredoxin PF00085.20 KIY73471.1 - 8.9e-18 64.2 0.0 1.3e-17 63.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 KIY73471.1 - 0.00052 19.5 0.0 0.00052 19.5 0.0 1.3 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 KIY73471.1 - 0.00057 20.3 0.1 0.0011 19.4 0.1 1.4 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 KIY73471.1 - 0.0056 16.5 0.0 0.0072 16.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KIY73471.1 - 0.0056 17.0 0.0 1.3 9.4 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin-like FixS PF03597.15 KIY73471.1 - 0.25 11.1 1.3 0.39 10.5 1.3 1.3 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type CENP-T_C PF15511.6 KIY73472.1 - 4.9e-07 29.9 0.0 5.9e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 KIY73472.1 - 3.4e-05 23.9 0.1 4.8e-05 23.5 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 KIY73472.1 - 0.0002 21.6 0.0 0.00026 21.3 0.0 1.3 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KIY73472.1 - 0.00085 19.6 0.1 0.0016 18.7 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KIY73472.1 - 0.00094 19.5 0.2 0.0011 19.4 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KIY73472.1 - 0.058 13.5 0.0 0.067 13.3 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KIY73472.1 - 0.14 12.2 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated DPBB_1 PF03330.18 KIY73474.1 - 0.0098 16.2 0.1 0.012 15.9 0.1 1.3 1 1 0 1 1 1 1 Lytic transglycolase Phytoreo_P8 PF07124.11 KIY73474.1 - 0.15 11.0 0.1 0.17 10.8 0.1 1.0 1 0 0 1 1 1 0 Phytoreovirus outer capsid protein P8 SPRR2 PF14820.6 KIY73475.1 - 0.12 12.4 1.8 14 5.8 0.2 2.5 2 0 0 2 2 2 0 Small proline-rich 2 Glyco_transf_22 PF03901.17 KIY73476.1 - 6.5e-78 262.8 18.7 9.4e-78 262.3 18.7 1.2 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family FtsX PF02687.21 KIY73477.1 - 0.073 13.6 9.5 0.23 12.0 0.1 2.8 2 1 0 2 2 2 0 FtsX-like permease family F-box PF00646.33 KIY73478.1 - 9.3e-06 25.4 0.3 2.5e-05 24.0 0.3 1.8 1 1 0 1 1 1 1 F-box domain F-box-like PF12937.7 KIY73478.1 - 5.1e-05 23.1 0.4 0.00013 21.8 0.4 1.7 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KIY73478.1 - 0.14 12.0 0.4 0.28 11.1 0.1 1.6 2 0 0 2 2 2 0 F-box ORC5_C PF14630.6 KIY73479.1 - 3.4e-57 194.1 0.0 4.3e-57 193.8 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus Peptidase_M28 PF04389.17 KIY73480.1 - 1.7e-35 122.5 0.1 3e-35 121.7 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M42 PF05343.14 KIY73480.1 - 0.026 13.6 0.0 0.078 12.0 0.0 1.7 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase Peptidase_M20 PF01546.28 KIY73480.1 - 0.031 14.0 0.0 0.063 13.0 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 CutC PF03932.14 KIY73481.1 - 4.3e-60 202.7 0.0 5.8e-60 202.3 0.0 1.2 1 0 0 1 1 1 1 CutC family FA_desaturase PF00487.24 KIY73482.1 - 1.2e-14 54.8 18.8 1.2e-14 54.8 18.8 1.5 1 1 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 KIY73482.1 - 0.00032 20.8 0.0 0.0012 19.0 0.0 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Bromodomain PF00439.25 KIY73483.1 - 3.9e-34 116.6 6.3 1.6e-18 66.6 0.1 2.7 3 0 0 3 3 3 2 Bromodomain PcfK PF14058.6 KIY73483.1 - 0.029 14.7 0.6 3.6 7.9 0.0 3.1 3 0 0 3 3 3 0 PcfK-like protein DUF3958 PF13125.6 KIY73483.1 - 0.56 10.4 6.4 0.23 11.7 1.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3958) Ceramidase PF05875.12 KIY73484.1 - 5.2e-76 255.5 5.3 6.3e-76 255.3 5.3 1.0 1 0 0 1 1 1 1 Ceramidase Peptidase_M16 PF00675.20 KIY73485.1 - 7.6e-36 123.3 0.0 1.4e-35 122.5 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KIY73485.1 - 4.6e-34 118.0 0.0 8.7e-34 117.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain Pyr_redox_2 PF07992.14 KIY73486.1 - 1.3e-31 110.0 0.0 1.7e-31 109.5 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIY73486.1 - 3.1e-13 50.1 0.2 8.9e-13 48.6 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIY73486.1 - 0.00063 19.4 0.1 0.65 9.5 0.0 3.0 1 1 2 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KIY73486.1 - 0.083 12.9 0.0 5.6 6.9 0.0 2.9 3 0 0 3 3 3 0 FAD-NAD(P)-binding UDPGP PF01704.18 KIY73487.1 - 9.5e-45 153.0 0.0 1.2e-44 152.6 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 KIY73487.1 - 0.014 15.8 0.0 0.031 14.6 0.0 1.6 1 0 0 1 1 1 0 MobA-like NTP transferase domain Taxilin PF09728.9 KIY73488.1 - 2.2e-18 66.5 32.0 1e-11 44.6 19.1 2.6 2 1 0 2 2 2 2 Myosin-like coiled-coil protein Rad60-SLD PF11976.8 KIY73488.1 - 6.9e-06 25.8 2.3 0.00019 21.2 0.3 3.0 2 1 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like PriA_C PF18074.1 KIY73488.1 - 0.00073 20.3 0.4 0.0049 17.7 0.1 2.6 1 1 1 2 2 2 1 Primosomal protein N C-terminal domain DUF2935 PF11155.8 KIY73488.1 - 0.0089 16.4 1.1 0.0089 16.4 1.1 2.0 2 1 0 2 2 2 1 Domain of unknown function (DUF2935) AIP3 PF03915.13 KIY73488.1 - 0.066 12.3 21.6 0.01 14.9 15.6 2.0 2 0 0 2 2 2 0 Actin interacting protein 3 Leu_zip PF15294.6 KIY73488.1 - 0.088 12.3 22.8 0.11 12.0 13.2 2.4 2 0 0 2 2 2 0 Leucine zipper Sec34 PF04136.15 KIY73488.1 - 0.28 11.0 6.7 0.11 12.3 4.1 1.7 2 0 0 2 2 2 0 Sec34-like family Prominin PF05478.11 KIY73488.1 - 0.86 7.5 14.6 0.062 11.3 9.9 1.4 2 0 0 2 2 2 0 Prominin DUF883 PF05957.13 KIY73488.1 - 1.1 9.9 15.8 1.3 9.6 3.4 4.2 3 2 1 4 4 4 0 Bacterial protein of unknown function (DUF883) Lectin_N PF03954.14 KIY73488.1 - 2.1 8.1 7.2 6 6.6 3.5 2.5 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain WD40_alt PF14077.6 KIY73488.1 - 2.2 8.2 5.9 6.6 6.7 0.1 3.2 4 0 0 4 4 4 0 Alternative WD40 repeat motif Atg14 PF10186.9 KIY73488.1 - 2.3 7.2 22.1 0.57 9.2 12.0 2.4 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 TMEM237 PF15383.6 KIY73488.1 - 2.7 7.0 3.7 3.2 6.8 2.9 1.4 1 1 0 1 1 1 0 Transmembrane protein 237 DUF948 PF06103.11 KIY73488.1 - 5.8 7.3 5.0 20 5.5 3.1 2.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) COG2 PF06148.11 KIY73488.1 - 6.9 6.8 13.1 1.1 9.4 3.2 2.9 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Fez1 PF06818.15 KIY73488.1 - 7.2 7.0 34.7 0.07 13.6 4.3 3.0 2 1 1 3 3 3 0 Fez1 UreE_C PF05194.12 KIY73488.1 - 9.2 6.8 11.5 15 6.1 6.5 3.1 3 0 0 3 3 3 0 UreE urease accessory protein, C-terminal domain MTCP1 PF08991.10 KIY73489.1 - 2.3e-20 72.5 4.1 2.6e-20 72.4 4.1 1.0 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type ARD PF03079.14 KIY73490.1 - 2.7e-42 144.6 0.0 3.1e-42 144.4 0.0 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 KIY73490.1 - 2.6e-09 36.6 0.0 4.6e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 KIY73490.1 - 9.4e-05 22.3 0.0 0.00016 21.6 0.0 1.5 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 KIY73490.1 - 0.018 14.6 0.0 0.029 14.0 0.0 1.3 1 0 0 1 1 1 0 Cupin Cupin_3 PF05899.12 KIY73490.1 - 0.05 13.3 0.0 0.1 12.3 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF861) Cupin_6 PF12852.7 KIY73490.1 - 0.14 11.9 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Cupin Lum_binding PF00677.17 KIY73491.1 - 1.6e-43 146.6 0.2 3.1e-22 78.3 0.0 2.1 2 0 0 2 2 2 2 Lumazine binding domain Trypsin_2 PF13365.6 KIY73493.1 - 6.6e-09 36.8 0.2 1.1e-08 36.1 0.2 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain BRCA-2_OB1 PF09103.10 KIY73494.1 - 6.5e-32 110.1 0.0 1.1e-31 109.3 0.0 1.4 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA-2_helical PF09169.10 KIY73494.1 - 1.5e-06 28.0 0.2 2.5e-06 27.3 0.2 1.3 1 0 0 1 1 1 1 BRCA2, helical APC_r PF05923.12 KIY73494.1 - 2.5 7.9 6.4 0.39 10.5 0.1 2.5 2 0 0 2 2 2 0 APC repeat DHHC PF01529.20 KIY73495.1 - 1.6e-36 125.4 8.0 1.6e-36 125.4 8.0 1.8 2 0 0 2 2 2 1 DHHC palmitoyltransferase Transglut_core3 PF13471.6 KIY73495.1 - 0.12 12.3 0.2 0.24 11.3 0.2 1.4 1 0 0 1 1 1 0 Transglutaminase-like superfamily PocR PF10114.9 KIY73495.1 - 0.51 10.1 2.7 0.78 9.5 2.7 1.2 1 0 0 1 1 1 0 Sensory domain found in PocR ACT_7 PF13840.6 KIY73497.1 - 4.3e-18 64.9 0.0 7.6e-18 64.1 0.0 1.4 1 0 0 1 1 1 1 ACT domain Ribonuclease_T2 PF00445.18 KIY73499.1 - 2.1e-41 142.2 0.9 3.2e-41 141.6 0.9 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family O-FucT PF10250.9 KIY73500.1 - 7e-14 52.3 0.0 5.5e-13 49.3 0.0 2.3 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase DNA_ligase_OB_2 PF14743.6 KIY73501.1 - 7.8e-27 93.1 0.1 1.7e-26 92.0 0.1 1.6 1 0 0 1 1 1 1 DNA ligase OB-like domain DNA_ligase_A_M PF01068.21 KIY73501.1 - 8.9e-10 38.5 0.0 2e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 ATP dependent DNA ligase domain zf-Nse PF11789.8 KIY73501.1 - 0.15 11.9 1.0 14 5.6 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit SWIM PF04434.17 KIY73501.1 - 0.2 11.3 4.7 6.7 6.5 0.3 2.6 2 0 0 2 2 2 0 SWIM zinc finger EGF PF00008.27 KIY73501.1 - 2 8.8 4.0 19 5.7 0.3 2.4 2 0 0 2 2 2 0 EGF-like domain RdRP PF05183.12 KIY73502.1 - 6.2e-144 480.8 0.0 8e-144 480.5 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase EF_TS PF00889.19 KIY73503.1 - 9.4e-18 64.6 0.0 4.5e-17 62.3 0.0 2.1 2 1 1 3 3 3 1 Elongation factor TS Bot1p PF12298.8 KIY73504.1 - 7.4e-22 78.3 0.4 2.7e-21 76.5 0.0 1.9 2 0 0 2 2 2 1 Eukaryotic mitochondrial regulator protein MRP-L20 PF12824.7 KIY73504.1 - 0.12 12.6 0.0 0.12 12.6 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial ribosomal protein subunit L20 Methyltransf_16 PF10294.9 KIY73505.1 - 1e-17 64.4 0.0 1.6e-17 63.8 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase FAM86 PF14904.6 KIY73505.1 - 0.0061 16.6 0.1 0.018 15.1 0.0 1.8 2 0 0 2 2 2 1 Family of unknown function GidB PF02527.15 KIY73505.1 - 0.074 12.4 0.1 0.98 8.7 0.0 2.3 2 0 0 2 2 2 0 rRNA small subunit methyltransferase G MTS PF05175.14 KIY73505.1 - 0.13 11.8 0.1 0.33 10.5 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain WLM PF08325.10 KIY73506.1 - 1e-58 198.6 0.1 1.4e-58 198.2 0.1 1.1 1 0 0 1 1 1 1 WLM domain zf-RanBP PF00641.18 KIY73506.1 - 6.2e-06 25.4 3.1 6.2e-06 25.4 3.1 3.1 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others DUF45 PF01863.17 KIY73506.1 - 0.0091 16.1 0.1 0.017 15.2 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function DUF45 C1_2 PF03107.16 KIY73506.1 - 0.12 12.7 6.1 3.8 7.9 0.2 3.2 2 1 1 3 3 3 0 C1 domain DZR PF12773.7 KIY73506.1 - 1.1 9.4 7.6 2.1 8.4 7.6 1.5 1 0 0 1 1 1 0 Double zinc ribbon WLM PF08325.10 KIY73507.1 - 3.3e-11 43.6 0.1 4.3e-11 43.2 0.1 1.1 1 0 0 1 1 1 1 WLM domain SH3_1 PF00018.28 KIY73508.1 - 5e-12 45.2 0.1 8.3e-12 44.5 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KIY73508.1 - 2.4e-09 36.9 0.0 3.8e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KIY73508.1 - 3.9e-08 32.9 0.0 6.4e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DUF1373 PF07117.11 KIY73508.1 - 0.0085 16.1 0.3 0.014 15.5 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1373) zf-C3HC4 PF00097.25 KIY73509.1 - 3.6e-09 36.3 8.5 6.2e-09 35.6 8.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KIY73509.1 - 6.4e-09 35.5 6.8 2.6e-07 30.4 8.3 2.2 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIY73509.1 - 4.8e-08 33.2 9.3 8e-08 32.5 9.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KIY73509.1 - 2e-07 30.8 5.4 3.3e-07 30.1 5.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KIY73509.1 - 8.2e-07 28.9 8.8 1.5e-06 28.1 5.6 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KIY73509.1 - 3.4e-05 23.7 7.2 6e-05 22.9 7.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KIY73509.1 - 0.00055 19.7 6.3 0.0019 18.0 6.7 1.7 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KIY73509.1 - 0.0018 18.4 9.4 0.0034 17.5 9.4 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 KIY73509.1 - 0.0058 16.9 6.2 0.011 16.0 6.2 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-Nse PF11789.8 KIY73509.1 - 0.007 16.2 3.9 0.015 15.1 3.9 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-ANAPC11 PF12861.7 KIY73509.1 - 0.026 14.6 4.5 0.048 13.7 4.5 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 KIY73509.1 - 0.06 13.1 9.0 0.58 10.0 4.3 2.6 2 0 0 2 2 2 0 RING-like zinc finger TerY_C PF15616.6 KIY73509.1 - 0.87 9.7 5.9 2.4 8.3 5.9 1.7 1 1 0 1 1 1 0 TerY-C metal binding domain zf-MIZ PF02891.20 KIY73509.1 - 5.3 6.9 9.3 12 5.8 9.3 1.6 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger Wbp11 PF09429.10 KIY73510.1 - 4.9e-22 78.1 10.8 1.1e-21 77.0 10.8 1.6 1 0 0 1 1 1 1 WW domain binding protein 11 NpwBP PF12622.7 KIY73510.1 - 1.6e-12 48.0 13.2 1.6e-12 48.0 13.2 5.4 2 1 1 3 3 3 1 mRNA biogenesis factor APG6_N PF17675.1 KIY73510.1 - 3.2 8.3 10.4 7 7.2 10.4 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region F-box-like PF12937.7 KIY73511.1 - 0.0046 16.8 0.1 0.011 15.7 0.1 1.7 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KIY73511.1 - 0.045 14.2 2.0 5 7.7 0.4 4.0 2 1 2 4 4 4 0 Leucine Rich repeats (2 copies) RicinB_lectin_2 PF14200.6 KIY73512.1 - 0.00034 21.3 0.0 0.0019 18.9 0.0 2.2 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain-like cNMP_binding PF00027.29 KIY73513.1 - 9.9e-31 105.7 0.8 7.9e-16 57.9 0.0 4.9 5 1 0 5 5 5 3 Cyclic nucleotide-binding domain Patatin PF01734.22 KIY73513.1 - 3e-17 63.5 8.7 5.3e-16 59.4 5.5 3.1 2 1 0 2 2 2 1 Patatin-like phospholipase Sec1 PF00995.23 KIY73514.1 - 8.1e-114 381.9 0.0 9.2e-114 381.7 0.0 1.0 1 0 0 1 1 1 1 Sec1 family YABBY PF04690.13 KIY73515.1 - 6e-06 26.9 3.0 6.4e-06 26.8 3.0 1.0 1 0 0 1 1 1 1 YABBY protein Ccdc124 PF06244.12 KIY73515.1 - 0.0006 20.4 3.1 0.00073 20.1 3.1 1.2 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 F-box-like PF12937.7 KIY73516.1 - 3.8e-05 23.5 0.0 0.00011 22.1 0.0 1.9 1 1 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KIY73516.1 - 0.0078 16.6 9.7 11 6.6 0.4 5.5 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) F-box PF00646.33 KIY73516.1 - 0.12 12.2 0.9 0.29 11.1 0.3 2.0 2 0 0 2 2 2 0 F-box domain Sas10_Utp3 PF04000.15 KIY73517.1 - 3.4e-18 66.1 0.1 8.3e-18 64.8 0.1 1.7 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Pox_J1 PF03338.15 KIY73517.1 - 0.062 13.1 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Poxvirus J1 protein Methyltransf_25 PF13649.6 KIY73518.1 - 3.2e-14 53.4 0.0 7.8e-14 52.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIY73518.1 - 6.7e-12 45.9 0.0 1.4e-11 44.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIY73518.1 - 3.3e-11 43.3 0.0 7e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIY73518.1 - 1.2e-06 28.4 0.0 2.5e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIY73518.1 - 2.3e-05 25.1 0.0 5e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KIY73518.1 - 0.00092 18.7 0.0 0.012 15.1 0.0 2.2 2 0 0 2 2 2 1 Putative methyltransferase FtsJ PF01728.19 KIY73518.1 - 0.0063 16.6 0.0 0.012 15.8 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 KIY73518.1 - 0.016 14.5 0.0 0.027 13.8 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Acyl-CoA_dh_1 PF00441.24 KIY73519.1 - 0.002 18.4 0.5 0.0037 17.5 0.5 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KIY73519.1 - 0.028 14.6 0.0 0.062 13.5 0.0 1.6 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, middle domain WD40 PF00400.32 KIY73520.1 - 1.4e-28 98.5 9.1 6.3e-06 26.8 0.1 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY73520.1 - 1.4e-09 38.1 0.5 0.001 19.3 0.0 5.1 3 2 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 KIY73520.1 - 5.4e-06 26.2 0.1 1.1e-05 25.1 0.1 1.6 1 0 0 1 1 1 1 LisH Ge1_WD40 PF16529.5 KIY73520.1 - 0.0014 17.6 0.0 0.09 11.7 0.0 2.3 2 0 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 KIY73520.1 - 0.024 14.0 0.0 5.2 6.3 0.0 3.1 3 0 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal WD40_like PF17005.5 KIY73520.1 - 0.033 13.5 0.0 0.23 10.7 0.0 2.2 2 0 0 2 2 2 0 WD40-like domain Bax1-I PF01027.20 KIY73521.1 - 1.2e-39 136.3 10.3 1.7e-39 135.8 10.3 1.2 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Acetyltransf_3 PF13302.7 KIY73522.1 - 1.2e-18 68.1 0.0 1.7e-18 67.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIY73522.1 - 5.2e-06 26.7 0.0 8.5e-06 26.0 0.0 1.6 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family DUF3128 PF11326.8 KIY73523.1 - 9e-20 70.8 2.7 1.1e-19 70.6 2.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) PNP_UDP_1 PF01048.20 KIY73525.1 - 1.9e-39 135.3 0.1 2.2e-39 135.1 0.1 1.2 1 0 0 1 1 1 1 Phosphorylase superfamily Sec1 PF00995.23 KIY73526.1 - 3.9e-121 406.1 0.0 4.5e-121 405.9 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Qua1 PF16274.5 KIY73526.1 - 0.04 13.7 0.9 0.1 12.4 0.1 2.0 2 0 0 2 2 2 0 Qua1 domain RSN1_7TM PF02714.15 KIY73527.1 - 2e-12 47.0 11.5 3.6e-12 46.2 11.5 1.3 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_ext PF12621.8 KIY73527.1 - 9.2e-05 22.5 0.0 0.0002 21.5 0.0 1.5 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter RSN1_TM PF13967.6 KIY73527.1 - 0.0001 22.1 0.2 0.0001 22.1 0.2 2.9 3 1 1 4 4 4 1 Late exocytosis, associated with Golgi transport SUR7 PF06687.12 KIY73528.1 - 1.4e-19 70.6 18.2 1.9e-19 70.1 18.2 1.1 1 0 0 1 1 1 1 SUR7/PalI family Arteri_Gl PF00951.18 KIY73528.1 - 0.038 13.8 1.1 0.076 12.8 1.1 1.4 1 0 0 1 1 1 0 Arterivirus GL envelope glycoprotein HIT PF01230.23 KIY73531.1 - 2.8e-22 79.3 0.0 4.2e-22 78.7 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KIY73531.1 - 1.5e-06 28.7 0.0 2e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding F-box-like PF12937.7 KIY73532.1 - 3.1e-06 27.0 0.0 9.1e-06 25.5 0.0 1.9 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KIY73532.1 - 0.0083 16.0 0.0 0.81 9.6 0.0 2.7 2 0 0 2 2 2 2 F-box domain Metallophos PF00149.28 KIY73533.1 - 5.2e-09 36.9 2.4 5.2e-09 36.9 2.4 1.9 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase PKD_3 PF16820.5 KIY73533.1 - 0.06 13.1 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 PKD-like domain YABBY PF04690.13 KIY73534.1 - 7.7e-08 33.1 0.4 8.4e-08 32.9 0.4 1.0 1 0 0 1 1 1 1 YABBY protein Ccdc124 PF06244.12 KIY73534.1 - 6.6e-05 23.5 1.9 8.8e-05 23.1 1.9 1.3 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 Arginase PF00491.21 KIY73537.1 - 1.9e-87 293.3 0.1 2.4e-87 293.0 0.1 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 KIY73537.1 - 0.011 15.9 0.0 0.019 15.2 0.0 1.3 1 0 0 1 1 1 0 UPF0489 domain WD40 PF00400.32 KIY73538.1 - 6.7e-16 58.4 19.4 0.003 18.4 0.2 7.2 6 1 1 7 7 7 4 WD domain, G-beta repeat Nup160 PF11715.8 KIY73538.1 - 0.057 12.1 0.4 0.76 8.3 0.0 2.7 4 0 0 4 4 4 0 Nucleoporin Nup120/160 Abhydrolase_6 PF12697.7 KIY73539.1 - 2.3e-12 48.0 0.2 3e-12 47.6 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KIY73539.1 - 0.011 15.4 0.0 0.02 14.6 0.0 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_M1 PF01433.20 KIY73540.1 - 9.7e-37 126.6 0.0 1.5e-36 126.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 KIY73540.1 - 6.2e-27 93.9 0.0 1e-26 93.2 0.0 1.4 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 KIY73540.1 - 8.8e-19 68.4 0.0 1.8e-18 67.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain TMEM154 PF15102.6 KIY73541.1 - 0.067 13.1 0.0 0.22 11.4 0.0 1.9 1 0 0 1 1 1 0 TMEM154 protein family FAM176 PF14851.6 KIY73541.1 - 0.78 9.4 3.2 1.5 8.5 0.0 2.7 2 1 1 3 3 3 0 FAM176 family Sin3a_C PF16879.5 KIY73542.1 - 8.1e-82 275.2 0.9 4.9e-81 272.6 0.0 2.8 4 0 0 4 4 4 1 C-terminal domain of Sin3a protein PAH PF02671.21 KIY73542.1 - 2.3e-38 130.0 7.8 1.7e-15 56.9 0.0 3.7 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 KIY73542.1 - 1.4e-37 127.7 0.2 2.8e-37 126.7 0.2 1.5 1 0 0 1 1 1 1 Sin3 family co-repressor CDC24_OB1 PF17246.2 KIY73542.1 - 0.027 14.6 0.0 0.063 13.4 0.0 1.6 1 0 0 1 1 1 0 Cell division control protein 24, OB domain 1 COX5A PF02284.16 KIY73542.1 - 0.027 14.5 0.1 2.9 7.9 0.0 3.4 3 0 0 3 3 3 0 Cytochrome c oxidase subunit Va Med28 PF11594.8 KIY73542.1 - 0.048 13.7 0.3 1.7 8.7 0.1 2.9 2 0 0 2 2 2 0 Mediator complex subunit 28 Vps39_1 PF10366.9 KIY73542.1 - 0.14 12.4 0.1 0.4 11.0 0.1 1.8 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 1 HEAT_EZ PF13513.6 KIY73543.1 - 0.0043 17.5 4.1 8.1 7.1 0.0 5.4 5 0 0 5 5 5 1 HEAT-like repeat Gcn1_N PF12074.8 KIY73543.1 - 0.075 12.3 0.1 0.72 9.1 0.0 2.3 1 1 1 2 2 2 0 Generalcontrol nonderepressible 1 (Gcn1) N-terminal KAP PF05804.12 KIY73543.1 - 0.099 10.8 0.0 0.43 8.6 0.0 1.8 2 0 0 2 2 2 0 Kinesin-associated protein (KAP) Arm PF00514.23 KIY73543.1 - 0.21 11.7 0.0 0.21 11.7 0.0 4.3 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat NAD_binding_2 PF03446.15 KIY73544.1 - 7.1e-25 88.0 0.0 1e-24 87.5 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 KIY73544.1 - 2.2e-08 34.2 0.0 1.2e-07 31.9 0.0 2.0 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_11 PF14833.6 KIY73544.1 - 2.2e-06 27.9 0.0 5.3e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_10 PF13460.6 KIY73544.1 - 8.6e-06 25.8 0.1 1.5e-05 25.0 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding F420_oxidored PF03807.17 KIY73544.1 - 1.5e-05 25.5 0.0 3.2e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh_N PF03721.14 KIY73544.1 - 0.052 13.1 0.6 0.073 12.6 0.0 1.5 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain OCD_Mu_crystall PF02423.15 KIY73544.1 - 0.12 11.3 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family CbiK PF06180.11 KIY73544.1 - 0.14 11.5 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Cobalt chelatase (CbiK) Pkinase PF00069.25 KIY73545.1 - 1.4e-38 132.8 0.0 2e-38 132.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY73545.1 - 4.7e-28 98.2 0.0 6.4e-28 97.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KIY73545.1 - 0.014 15.4 0.1 0.081 12.8 0.1 2.2 1 1 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KIY73545.1 - 0.03 13.3 0.0 0.046 12.7 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Ctr PF04145.15 KIY73546.1 - 9e-05 23.1 5.1 9e-05 23.1 5.1 2.5 2 2 1 3 3 3 1 Ctr copper transporter family Exo5 PF09810.9 KIY73547.1 - 2.6e-67 227.9 0.0 4e-64 217.4 0.0 2.9 1 1 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.7 KIY73547.1 - 0.084 12.8 0.1 3.2 7.6 0.0 2.6 3 0 0 3 3 3 0 PD-(D/E)XK nuclease superfamily MFS_1 PF07690.16 KIY73548.1 - 6.1e-10 38.6 60.4 7.2e-07 28.4 19.5 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KIY73548.1 - 1.7e-08 33.4 30.2 2.9e-08 32.6 30.2 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Plasmid_stab_B PF10784.9 KIY73548.1 - 0.099 12.5 0.7 9.1 6.2 0.0 3.0 2 1 1 3 3 3 0 Plasmid stability protein Alg6_Alg8 PF03155.15 KIY73549.1 - 5e-125 418.2 22.4 7.9e-125 417.6 22.4 1.2 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family ALG3 PF05208.13 KIY73549.1 - 0.00029 20.4 4.4 0.00036 20.1 2.5 1.7 1 1 1 2 2 2 1 ALG3 protein RTA1 PF04479.13 KIY73550.1 - 7.1e-43 146.6 5.6 7.1e-43 146.6 5.6 1.6 2 0 0 2 2 2 1 RTA1 like protein H_PPase PF03030.16 KIY73550.1 - 0.042 12.5 0.5 0.056 12.1 0.5 1.3 1 0 0 1 1 1 0 Inorganic H+ pyrophosphatase TMEM100 PF16311.5 KIY73550.1 - 0.14 11.8 2.4 0.11 12.0 0.5 1.9 2 0 0 2 2 2 0 Transmembrane protein 100 Abhydrolase_3 PF07859.13 KIY73551.1 - 1.2e-17 64.5 0.0 2.4e-17 63.5 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KIY73551.1 - 1.5e-06 27.4 0.0 2.4e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase COesterase PF00135.28 KIY73551.1 - 0.0052 15.7 0.0 0.056 12.3 0.0 1.9 2 0 0 2 2 2 1 Carboxylesterase family HA2 PF04408.23 KIY73553.1 - 3e-20 72.5 0.1 3.4e-19 69.1 0.0 2.6 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KIY73553.1 - 7.2e-17 61.5 0.0 1.6e-16 60.4 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KIY73553.1 - 1.1e-11 45.0 0.0 2.6e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KIY73553.1 - 6.6e-10 39.0 0.1 1.7e-09 37.7 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KIY73553.1 - 0.0014 18.9 0.4 0.0061 16.8 0.4 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 KIY73553.1 - 0.012 15.6 0.0 0.039 13.9 0.0 1.9 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit ABC_tran PF00005.27 KIY73553.1 - 0.013 16.0 0.0 0.42 11.1 0.0 2.9 2 0 0 2 2 2 0 ABC transporter DND1_DSRM PF14709.7 KIY73553.1 - 0.032 14.5 0.1 0.076 13.3 0.1 1.7 1 0 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 ATPase PF06745.13 KIY73553.1 - 0.043 13.2 0.0 0.083 12.2 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_30 PF13604.6 KIY73553.1 - 0.054 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain RuvA_C PF07499.13 KIY73553.1 - 0.057 13.9 0.2 5.2 7.6 0.0 4.0 5 0 0 5 5 5 0 RuvA, C-terminal domain AAA_19 PF13245.6 KIY73553.1 - 0.068 13.5 0.0 0.16 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KIY73553.1 - 0.13 12.7 0.3 1 9.7 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain AAA_14 PF13173.6 KIY73553.1 - 0.13 12.3 0.0 2 8.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain HA2 PF04408.23 KIY73554.1 - 8.4e-26 90.4 0.2 3e-25 88.6 0.2 2.0 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KIY73554.1 - 1.8e-24 85.9 0.0 3.5e-24 85.0 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KIY73554.1 - 1.1e-12 48.2 0.0 3.7e-12 46.6 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.23 KIY73554.1 - 3e-08 33.9 0.2 6.5e-08 32.8 0.2 1.6 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.29 KIY73554.1 - 1.9e-05 24.5 0.1 3.5e-05 23.6 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KIY73554.1 - 6.4e-05 23.2 0.1 0.00016 22.0 0.1 1.6 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 KIY73554.1 - 7.2e-05 23.3 0.3 0.086 13.4 0.1 3.2 2 1 0 2 2 2 1 ABC transporter T2SSE PF00437.20 KIY73554.1 - 0.0008 18.6 0.1 0.0024 17.0 0.1 1.8 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF2075 PF09848.9 KIY73554.1 - 0.0014 18.0 0.0 0.003 16.9 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 KIY73554.1 - 0.0041 16.8 0.0 0.011 15.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KIY73554.1 - 0.029 14.7 0.1 0.064 13.6 0.1 1.6 1 0 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.14 KIY73554.1 - 0.052 13.5 0.1 0.12 12.4 0.1 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain Microtub_bd PF16796.5 KIY73554.1 - 0.068 13.1 0.0 1.3 9.0 0.0 2.4 2 0 0 2 2 2 0 Microtubule binding PhoH PF02562.16 KIY73554.1 - 0.11 12.0 0.0 0.26 10.7 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein UPF0093 PF03653.13 KIY73555.1 - 0.023 15.0 0.4 2.4 8.4 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0093) OAD_gamma PF04277.13 KIY73555.1 - 0.062 13.9 0.4 4.5 7.9 0.1 2.4 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain C2 PF00168.30 KIY73556.1 - 7.3e-09 35.8 0.0 1.1e-08 35.3 0.0 1.3 1 0 0 1 1 1 1 C2 domain ADH_zinc_N PF00107.26 KIY73557.1 - 1.6e-12 47.5 0.0 3.2e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KIY73557.1 - 0.00061 20.8 0.0 0.0021 19.1 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Exo_endo_phos PF03372.23 KIY73558.1 - 2.8e-18 66.3 0.0 3.5e-18 66.0 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family TauE PF01925.19 KIY73558.1 - 0.026 14.1 0.8 0.047 13.3 0.8 1.3 1 0 0 1 1 1 0 Sulfite exporter TauE/SafE DUF2244 PF10003.9 KIY73558.1 - 1.5 8.5 3.9 3 7.5 3.9 1.4 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) Peptidase_M24 PF00557.24 KIY73559.1 - 9.6e-42 143.0 0.1 1.3e-41 142.7 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 YL1 PF05764.13 KIY73559.1 - 0.022 14.9 8.9 0.033 14.3 8.9 1.2 1 0 0 1 1 1 0 YL1 nuclear protein CDT1_C PF16679.5 KIY73559.1 - 0.16 12.4 0.0 0.39 11.2 0.0 1.5 1 0 0 1 1 1 0 DNA replication factor Cdt1 C-terminal domain PGA2 PF07543.12 KIY73559.1 - 8.5 6.4 12.2 4.2 7.4 3.1 3.1 3 0 0 3 3 3 0 Protein trafficking PGA2 Abhydrolase_3 PF07859.13 KIY73560.1 - 1.7e-48 165.3 0.0 3.2e-48 164.4 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KIY73560.1 - 6.4e-14 51.6 0.0 5.9e-12 45.1 0.0 2.1 2 0 0 2 2 2 2 Steryl acetyl hydrolase Abhydrolase_1 PF00561.20 KIY73560.1 - 0.024 14.3 0.1 0.04 13.6 0.1 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold COesterase PF00135.28 KIY73560.1 - 0.039 12.8 0.0 1.8 7.4 0.0 2.2 2 0 0 2 2 2 0 Carboxylesterase family NTF2 PF02136.20 KIY73561.1 - 4.2e-10 40.2 0.0 1.3e-09 38.6 0.0 1.7 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.9 KIY73561.1 - 0.00035 20.5 0.0 0.00045 20.2 0.0 1.1 1 0 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 F-box-like PF12937.7 KIY73563.1 - 0.00018 21.3 4.8 0.00058 19.7 3.5 2.6 2 1 0 2 2 2 1 F-box-like N_BRCA1_IG PF16158.5 KIY73564.1 - 2.2e-26 92.5 0.0 4.7e-26 91.5 0.0 1.6 1 0 0 1 1 1 1 Ig-like domain from next to BRCA1 gene ZZ PF00569.17 KIY73564.1 - 2.5e-22 78.4 43.4 8.6e-10 38.3 5.8 4.3 4 0 0 4 4 4 3 Zinc finger, ZZ type C1_2 PF03107.16 KIY73564.1 - 1.5e-05 25.2 41.0 0.0048 17.2 2.5 4.4 4 0 0 4 4 4 3 C1 domain Aminotran_4 PF01063.19 KIY73565.1 - 2.9e-21 76.3 0.0 3.2e-21 76.2 0.0 1.0 1 0 0 1 1 1 1 Amino-transferase class IV WD40 PF00400.32 KIY73566.1 - 1.5e-58 193.3 18.4 2.3e-05 25.1 0.0 12.3 12 0 0 12 12 12 11 WD domain, G-beta repeat Utp13 PF08625.11 KIY73566.1 - 2.7e-49 166.7 0.1 4.4e-49 166.0 0.1 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 KIY73566.1 - 3.1e-11 43.4 1.8 0.58 10.5 0.0 7.6 5 2 3 8 8 8 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KIY73566.1 - 1.2e-05 24.2 3.3 2.6 6.6 0.1 4.7 5 0 0 5 5 5 4 Nucleoporin Nup120/160 WD40_like PF17005.5 KIY73566.1 - 4.1e-05 23.0 0.0 0.0021 17.5 0.0 3.2 3 0 0 3 3 3 1 WD40-like domain Ge1_WD40 PF16529.5 KIY73566.1 - 0.0031 16.5 1.2 9.2 5.1 0.0 4.4 3 1 2 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein VID27 PF08553.10 KIY73566.1 - 0.015 14.4 0.3 0.89 8.5 0.0 3.2 4 0 0 4 4 4 0 VID27 C-terminal WD40-like domain Forkhead PF00250.18 KIY73567.1 - 1.7e-19 69.8 0.0 3.3e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain DUF4200 PF13863.6 KIY73567.1 - 0.035 14.5 7.1 0.061 13.7 7.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Dscam_C PF12355.8 KIY73567.1 - 0.14 13.1 6.6 0.33 11.9 6.5 1.8 1 1 0 1 1 1 0 Down syndrome cell adhesion molecule C terminal Spc7 PF08317.11 KIY73567.1 - 0.14 11.0 5.4 0.22 10.4 5.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Fungal_trans PF04082.18 KIY73568.1 - 1.6e-30 106.1 0.0 2.7e-30 105.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY73568.1 - 2e-06 27.8 9.7 3e-06 27.2 9.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Oxidored_FMN PF00724.20 KIY73569.1 - 1.2e-95 320.7 0.0 1.4e-95 320.5 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family NIPSNAP PF07978.13 KIY73570.1 - 1.5e-30 105.4 3.8 1.1e-24 86.5 0.6 2.2 2 0 0 2 2 2 2 NIPSNAP Glycos_transf_2 PF00535.26 KIY73571.1 - 0.0085 15.9 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 MSP1b PF03429.13 KIY73571.1 - 0.033 12.3 0.0 0.043 11.9 0.0 1.1 1 0 0 1 1 1 0 Major surface protein 1B CSTF_C PF14304.6 KIY73571.1 - 2.8 7.6 3.8 5.8 6.6 0.1 2.8 3 0 0 3 3 3 0 Transcription termination and cleavage factor C-terminal MoaC PF01967.21 KIY73572.1 - 6.4e-49 165.5 1.7 1e-48 164.9 1.7 1.4 1 0 0 1 1 1 1 MoaC family Mob_synth_C PF06463.13 KIY73572.1 - 3.5e-39 133.6 0.0 6e-39 132.9 0.0 1.4 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 KIY73572.1 - 8.9e-25 88.0 0.0 3e-24 86.3 0.0 2.0 3 0 0 3 3 3 1 Radical SAM superfamily Fer4_12 PF13353.6 KIY73572.1 - 1.9e-07 31.4 0.0 3.1e-06 27.5 0.0 2.6 3 0 0 3 3 3 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 KIY73572.1 - 0.013 15.6 0.0 0.044 13.9 0.0 1.8 2 0 0 2 2 2 0 4Fe-4S single cluster domain DUF953 PF06110.11 KIY73573.1 - 1.7e-16 59.9 0.1 2.1e-16 59.6 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin PF00085.20 KIY73573.1 - 0.0023 17.9 0.1 0.0055 16.7 0.1 1.6 1 1 0 1 1 1 1 Thioredoxin Mito_carr PF00153.27 KIY73574.1 - 8.2e-64 211.6 1.6 3.5e-23 81.3 0.0 3.8 4 0 0 4 4 4 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 KIY73574.1 - 6.2e-19 68.2 5.2 7.4e-06 26.3 0.1 4.7 3 2 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 KIY73574.1 - 2.6e-18 64.1 6.3 1.2e-06 27.6 0.3 6.1 6 0 0 6 6 6 3 EF hand EF-hand_6 PF13405.6 KIY73574.1 - 3.7e-16 57.6 6.2 2.4e-05 23.9 0.2 5.9 6 0 0 6 6 6 2 EF-hand domain EF-hand_8 PF13833.6 KIY73574.1 - 8.3e-12 44.8 4.2 0.00011 21.9 0.0 4.8 4 1 1 5 5 5 2 EF-hand domain pair EF-hand_5 PF13202.6 KIY73574.1 - 2.9e-08 32.8 8.1 0.00018 20.9 0.3 4.6 4 0 0 4 4 4 2 EF hand Met_10 PF02475.16 KIY73575.1 - 1.8e-62 210.7 0.0 2.3e-62 210.3 0.0 1.1 1 0 0 1 1 1 1 Met-10+ like-protein TRM PF02005.16 KIY73575.1 - 0.00032 20.0 0.0 0.00061 19.1 0.0 1.4 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase TehB PF03848.14 KIY73575.1 - 0.0022 17.4 0.0 0.0038 16.7 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB MethyltransfD12 PF02086.15 KIY73575.1 - 0.0044 16.7 0.0 0.0074 16.0 0.0 1.3 1 0 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase tRNA_U5-meth_tr PF05958.11 KIY73575.1 - 0.019 14.0 0.0 0.03 13.3 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Methyltransf_15 PF09445.10 KIY73575.1 - 0.051 13.1 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase PrmA PF06325.13 KIY73575.1 - 0.054 12.9 0.0 0.086 12.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.7 KIY73575.1 - 0.099 12.6 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 KIY73575.1 - 0.18 12.5 0.0 0.45 11.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain TatD_DNase PF01026.21 KIY73576.1 - 2.2e-26 92.8 0.0 2.8e-26 92.4 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Tfb5 PF06331.12 KIY73577.1 - 0.059 13.4 0.0 1.6 8.7 0.0 2.4 2 1 0 2 2 2 0 Transcription factor TFIIH complex subunit Tfb5 V-SNARE_C PF12352.8 KIY73578.1 - 1.3e-14 54.2 3.6 5.2e-13 49.1 0.3 3.2 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 KIY73578.1 - 0.0044 16.9 0.0 0.028 14.3 0.0 2.2 2 1 0 2 2 2 1 Sec20 Tropomyosin_1 PF12718.7 KIY73578.1 - 0.011 15.8 5.0 0.02 15.1 5.0 1.4 1 1 0 1 1 1 0 Tropomyosin like DivIVA PF05103.13 KIY73578.1 - 0.034 14.2 0.8 0.034 14.2 0.8 2.1 2 0 0 2 2 2 0 DivIVA protein Nup54 PF13874.6 KIY73578.1 - 0.05 13.7 1.1 0.21 11.7 0.2 2.3 2 1 0 2 2 2 0 Nucleoporin complex subunit 54 Med30 PF11315.8 KIY73578.1 - 0.1 12.8 1.4 0.17 12.1 0.3 1.8 1 1 1 2 2 2 0 Mediator complex subunit 30 TMPIT PF07851.13 KIY73578.1 - 0.14 11.4 0.7 0.22 10.7 0.7 1.4 1 0 0 1 1 1 0 TMPIT-like protein AbiH PF14253.6 KIY73578.1 - 0.14 12.0 0.2 0.16 11.8 0.2 1.2 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH FTO_CTD PF12934.7 KIY73578.1 - 0.15 11.8 1.2 0.36 10.6 0.6 1.8 1 1 1 2 2 2 0 FTO C-terminal domain FapA PF03961.13 KIY73578.1 - 0.16 10.6 0.5 0.18 10.4 0.5 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A CENP-H PF05837.12 KIY73578.1 - 0.18 12.2 3.1 0.24 11.8 1.3 2.0 1 1 1 2 2 2 0 Centromere protein H (CENP-H) BST2 PF16716.5 KIY73578.1 - 0.38 11.4 4.9 0.3 11.7 1.2 2.4 3 0 0 3 3 3 0 Bone marrow stromal antigen 2 Seryl_tRNA_N PF02403.22 KIY73578.1 - 0.52 10.6 3.6 1.1 9.6 0.8 2.2 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain APG6_N PF17675.1 KIY73578.1 - 0.58 10.7 8.6 1.3 9.5 6.7 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region AATF-Che1 PF13339.6 KIY73578.1 - 0.71 10.5 3.6 1.2 9.8 3.6 1.5 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor NIPSNAP PF07978.13 KIY73579.1 - 0.036 14.3 0.0 0.09 13.0 0.0 1.7 1 0 0 1 1 1 0 NIPSNAP ZapB PF06005.12 KIY73579.1 - 0.22 12.0 2.9 0.55 10.7 2.9 1.6 1 0 0 1 1 1 0 Cell division protein ZapB Cupin_5 PF06172.11 KIY73580.1 - 1.6e-41 141.8 0.0 1.8e-41 141.6 0.0 1.0 1 0 0 1 1 1 1 Cupin superfamily (DUF985) FCH PF00611.23 KIY73581.1 - 2.2e-13 50.3 0.8 1.1e-12 48.0 0.0 2.5 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 KIY73581.1 - 1.1e-10 40.9 0.2 2.3e-10 39.9 0.2 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KIY73581.1 - 1.5e-09 37.5 0.1 2.9e-09 36.6 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KIY73581.1 - 2.3e-05 24.0 0.0 4.4e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DUF3090 PF11290.8 KIY73581.1 - 0.073 12.9 1.8 0.14 12.0 1.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3090) TMF_DNA_bd PF12329.8 KIY73581.1 - 0.13 12.2 2.1 4.6 7.3 0.0 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF4795 PF16043.5 KIY73581.1 - 0.14 11.7 9.2 0.22 11.1 9.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) Exonuc_VII_L PF02601.15 KIY73581.1 - 0.64 9.5 3.8 0.98 8.9 3.8 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4407 PF14362.6 KIY73581.1 - 1 8.6 7.8 1.5 8.1 7.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) LMBR1 PF04791.16 KIY73581.1 - 6.4 5.6 5.1 8.4 5.2 5.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Lgl_C PF08596.10 KIY73582.1 - 1.5e-34 119.3 0.0 3.6e-34 118.1 0.0 1.5 1 1 0 1 1 1 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.32 KIY73582.1 - 0.0053 17.6 1.9 0.83 10.6 0.0 4.6 5 0 0 5 5 5 1 WD domain, G-beta repeat Nucleoporin_N PF08801.11 KIY73582.1 - 0.016 14.0 0.0 3.3 6.4 0.0 3.0 2 1 1 3 3 3 0 Nup133 N terminal like ANAPC4_WD40 PF12894.7 KIY73582.1 - 0.024 14.9 0.0 1.5 9.2 0.0 3.7 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain FAT PF02259.23 KIY73583.1 - 2.2e-111 372.4 6.1 2.2e-111 372.4 6.1 2.1 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 KIY73583.1 - 9.9e-70 235.2 0.2 3.7e-68 230.0 0.1 2.6 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 KIY73583.1 - 4.3e-55 186.0 11.2 1.1e-52 178.2 0.5 6.9 7 1 1 8 8 8 1 Domain of unknown function (DUF3385) FRB_dom PF08771.11 KIY73583.1 - 7.3e-39 132.2 0.2 9e-38 128.7 0.0 3.2 2 0 0 2 2 1 1 FKBP12-rapamycin binding domain HEAT_2 PF13646.6 KIY73583.1 - 1.8e-14 53.9 6.0 0.022 15.1 0.0 8.9 8 1 0 8 8 7 2 HEAT repeats FATC PF02260.20 KIY73583.1 - 3.7e-13 49.0 0.1 1.5e-12 47.1 0.1 2.2 1 0 0 1 1 1 1 FATC domain HEAT_EZ PF13513.6 KIY73583.1 - 5.3e-12 46.0 10.4 0.00024 21.5 0.0 8.9 8 1 1 9 9 7 2 HEAT-like repeat HEAT PF02985.22 KIY73583.1 - 3.1e-08 33.2 13.5 1.2 9.5 0.1 9.3 9 0 0 9 9 8 1 HEAT repeat Vac14_Fab1_bd PF12755.7 KIY73583.1 - 7e-07 29.8 1.4 72 4.1 0.0 8.0 6 3 3 10 10 10 0 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KIY73583.1 - 9.6e-07 29.0 9.6 0.0045 17.0 0.2 5.4 5 1 1 6 6 6 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 KIY73583.1 - 2.6e-06 26.3 13.2 0.0008 18.1 2.5 5.2 5 1 0 5 5 5 2 Adaptin N terminal region Proteasom_PSMB PF10508.9 KIY73583.1 - 2.2e-05 23.2 1.6 0.00048 18.8 0.1 3.5 4 0 0 4 4 4 1 Proteasome non-ATPase 26S subunit UME PF08064.13 KIY73583.1 - 0.00072 19.4 4.3 5 7.1 0.5 5.2 4 0 0 4 4 4 1 UME (NUC010) domain TPR_19 PF14559.6 KIY73583.1 - 0.014 15.9 0.2 24 5.5 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KIY73583.1 - 0.016 15.3 3.1 19 5.7 0.1 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 KIY73583.1 - 0.025 14.6 0.5 6 7.1 0.1 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KIY73583.1 - 0.13 12.5 2.3 18 5.6 0.0 4.2 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 KIY73583.1 - 0.33 10.9 1.4 30 4.6 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat IFRD PF05004.13 KIY73583.1 - 0.41 9.7 7.1 30 3.6 0.0 5.1 5 1 1 6 6 6 0 Interferon-related developmental regulator (IFRD) RIX1 PF08167.12 KIY73583.1 - 3.7 7.2 7.2 37 4.0 0.1 5.1 4 1 0 4 4 4 0 rRNA processing/ribosome biogenesis RhoGEF PF00621.20 KIY73584.1 - 1.7e-12 47.9 0.3 3.7e-11 43.6 0.1 2.1 2 0 0 2 2 2 2 RhoGEF domain Glyco_hydro_43 PF04616.14 KIY73585.1 - 9.2e-66 222.1 0.5 2e-65 221.0 0.3 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KIY73585.1 - 1.2e-33 116.5 0.0 2e-33 115.8 0.0 1.2 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain YbjN PF10722.9 KIY73585.1 - 0.46 10.6 2.8 34 4.5 0.0 3.2 3 0 0 3 3 3 0 Putative bacterial sensory transduction regulator Glycos_transf_3 PF00591.21 KIY73586.1 - 3.9e-75 252.7 0.0 4.9e-75 252.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 KIY73586.1 - 6.5e-10 38.7 0.0 1.8e-09 37.3 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family, helical bundle domain GSH_synth_ATP PF03917.17 KIY73587.1 - 1.1e-128 429.2 0.0 1.3e-128 429.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 KIY73587.1 - 5.6e-34 116.7 0.0 1e-33 115.8 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic glutathione synthase Carn_acyltransf PF00755.20 KIY73588.1 - 2.2e-157 525.2 0.0 2.5e-157 525.1 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase zf-RING_2 PF13639.6 KIY73589.1 - 7.2e-11 42.2 6.4 7.2e-11 42.2 6.4 2.2 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 KIY73589.1 - 4.9e-10 39.5 5.8 4.9e-10 39.5 5.8 1.8 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KIY73589.1 - 1e-07 31.8 3.9 1e-07 31.8 3.9 2.3 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KIY73589.1 - 2.2e-07 30.6 8.7 2.2e-07 30.6 8.7 2.7 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KIY73589.1 - 3.9e-07 30.0 0.6 8.7e-07 28.9 0.6 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 KIY73589.1 - 9.6e-07 28.6 5.6 9.6e-07 28.6 5.6 2.3 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIY73589.1 - 5.6e-06 26.2 4.3 5.6e-06 26.2 4.3 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_11 PF17123.5 KIY73589.1 - 4.3e-05 23.2 6.9 0.00016 21.3 6.9 2.0 1 1 0 1 1 1 1 RING-like zinc finger zinc_ribbon_9 PF14369.6 KIY73589.1 - 0.00063 20.0 0.7 0.00063 20.0 0.7 2.7 3 0 0 3 3 3 1 zinc-ribbon zf-C3HC4_3 PF13920.6 KIY73589.1 - 0.0011 18.7 3.2 0.0011 18.7 3.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 KIY73589.1 - 0.032 14.1 2.1 0.032 14.1 2.1 2.9 3 1 0 3 3 3 0 PHD-finger DZR PF12773.7 KIY73589.1 - 0.09 12.8 7.7 0.57 10.2 0.3 3.0 2 1 0 3 3 3 0 Double zinc ribbon Inhibitor_I71 PF12628.7 KIY73589.1 - 0.19 11.5 0.9 0.3 10.9 0.9 1.3 1 0 0 1 1 1 0 Falstatin, cysteine peptidase inhibitor HypA PF01155.19 KIY73589.1 - 0.24 11.5 2.9 8.2 6.5 0.1 2.2 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn_ribbon_17 PF17120.5 KIY73589.1 - 0.26 10.9 5.0 0.74 9.5 5.0 1.8 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 KIY73589.1 - 0.46 10.7 5.0 5.1 7.3 5.0 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain DUF2256 PF10013.9 KIY73589.1 - 0.81 9.9 4.3 2 8.6 0.1 3.0 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) Nudix_N_2 PF14803.6 KIY73589.1 - 6.7 6.7 7.2 28 4.7 0.0 3.7 4 0 0 4 4 4 0 Nudix N-terminal DNA_RNApol_7kD PF03604.13 KIY73589.1 - 7.8 6.3 5.6 28 4.5 0.1 2.9 2 1 1 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit ABC_tran PF00005.27 KIY73590.1 - 5.8e-53 179.1 0.0 5e-29 101.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KIY73590.1 - 1.9e-52 178.6 20.5 2.4e-32 112.7 5.2 2.8 2 1 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 KIY73590.1 - 7.1e-12 45.2 1.6 3.2e-05 23.5 0.1 4.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KIY73590.1 - 1.6e-08 34.1 0.6 0.00046 19.9 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KIY73590.1 - 6.1e-07 30.0 1.2 0.023 15.1 0.0 3.3 3 1 0 3 3 2 2 AAA ATPase domain AAA_23 PF13476.6 KIY73590.1 - 6.3e-07 30.1 0.9 0.00023 21.7 0.2 2.4 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 KIY73590.1 - 1.4e-06 27.5 2.7 0.003 16.7 0.1 2.5 3 0 0 3 3 2 2 Type II/IV secretion system protein DUF87 PF01935.17 KIY73590.1 - 1.4e-05 25.3 1.6 0.0039 17.3 0.1 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_22 PF13401.6 KIY73590.1 - 1.9e-05 25.0 0.8 0.2 11.9 0.1 2.9 2 1 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 KIY73590.1 - 7.1e-05 22.2 0.4 0.064 12.5 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin RsgA_GTPase PF03193.16 KIY73590.1 - 0.00015 21.8 0.1 0.089 12.7 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 KIY73590.1 - 0.00025 21.1 0.4 0.13 12.3 0.1 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_30 PF13604.6 KIY73590.1 - 0.00025 20.8 0.5 0.94 9.2 0.1 2.9 2 1 0 2 2 2 2 AAA domain cobW PF02492.19 KIY73590.1 - 0.00038 20.1 1.0 0.057 13.0 0.1 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 KIY73590.1 - 0.00041 19.9 0.3 0.88 9.1 0.1 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_25 PF13481.6 KIY73590.1 - 0.00078 19.1 1.9 0.17 11.4 0.5 3.0 2 1 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 KIY73590.1 - 0.00089 19.4 0.1 1.7 8.6 0.3 2.5 2 0 0 2 2 2 2 Dynamin family AAA_33 PF13671.6 KIY73590.1 - 0.0011 19.2 0.1 0.93 9.6 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_21 PF13304.6 KIY73590.1 - 0.0014 18.5 0.1 1.8 8.3 0.1 3.3 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system NACHT PF05729.12 KIY73590.1 - 0.0015 18.4 1.6 1.3 8.9 0.1 2.8 2 0 0 2 2 2 2 NACHT domain AAA_18 PF13238.6 KIY73590.1 - 0.0016 19.0 0.7 0.63 10.6 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA PF00004.29 KIY73590.1 - 0.0021 18.5 0.3 7.4 7.0 0.0 3.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.18 KIY73590.1 - 0.0031 16.9 1.1 0.89 8.9 0.0 2.6 3 0 0 3 3 2 1 FtsK/SpoIIIE family RNA_helicase PF00910.22 KIY73590.1 - 0.0032 17.9 0.1 1.9 8.9 0.0 2.7 2 0 0 2 2 2 1 RNA helicase TrwB_AAD_bind PF10412.9 KIY73590.1 - 0.0064 15.5 0.9 0.89 8.4 0.1 2.3 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain IstB_IS21 PF01695.17 KIY73590.1 - 0.011 15.5 0.4 5.6 6.7 0.0 2.6 3 0 0 3 3 2 0 IstB-like ATP binding protein CbiA PF01656.23 KIY73590.1 - 0.016 15.3 0.0 1.6 8.8 0.0 2.8 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Adeno_IVa2 PF02456.15 KIY73590.1 - 0.016 14.0 0.4 0.41 9.4 0.1 2.3 2 0 0 2 2 2 0 Adenovirus IVa2 protein NB-ARC PF00931.22 KIY73590.1 - 0.047 12.9 1.7 0.3 10.2 0.1 2.5 3 0 0 3 3 3 0 NB-ARC domain AAA_5 PF07728.14 KIY73590.1 - 0.047 13.7 1.2 3.2 7.8 0.1 3.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.18 KIY73590.1 - 0.054 13.2 0.3 5.2 6.7 0.1 2.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase ATP_bind_1 PF03029.17 KIY73590.1 - 0.066 13.0 1.3 1.8 8.3 0.0 2.9 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Sigma54_activat PF00158.26 KIY73590.1 - 0.077 12.7 0.0 6.6 6.4 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain ATPase PF06745.13 KIY73590.1 - 0.082 12.2 0.6 2.7 7.3 0.1 2.7 3 0 0 3 3 3 0 KaiC AAA_11 PF13086.6 KIY73590.1 - 0.087 12.6 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KIY73590.1 - 0.12 11.6 0.6 1.5 8.0 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) MeaB PF03308.16 KIY73590.1 - 0.12 11.3 0.6 0.24 10.3 0.1 1.6 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_15 PF13175.6 KIY73590.1 - 0.15 11.7 0.0 21 4.7 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain DEAD PF00270.29 KIY73590.1 - 0.17 11.6 0.2 19 5.0 0.0 3.1 3 0 0 3 3 3 0 DEAD/DEAH box helicase MobB PF03205.14 KIY73590.1 - 0.2 11.5 0.4 6.9 6.6 0.1 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Mg_chelatase PF01078.21 KIY73590.1 - 0.23 10.8 0.4 11 5.3 0.0 2.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.15 KIY73590.1 - 0.48 10.3 3.4 2 8.3 0.1 2.9 3 0 0 3 3 3 0 NTPase SecE PF00584.20 KIY73591.1 - 0.25 11.3 1.1 0.45 10.5 1.1 1.3 1 0 0 1 1 1 0 SecE/Sec61-gamma subunits of protein translocation complex DUF89 PF01937.19 KIY73593.1 - 1.1e-108 363.3 0.1 1.4e-108 363.0 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 DUF3483 PF11982.8 KIY73594.1 - 0.17 11.5 0.2 0.22 11.1 0.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3483) Filament PF00038.21 KIY73595.1 - 0.0018 17.9 4.0 0.0018 17.9 4.0 3.1 2 1 1 3 3 3 2 Intermediate filament protein SPATA1_C PF15743.5 KIY73595.1 - 0.0046 17.0 2.3 0.0046 17.0 2.3 3.4 2 2 1 3 3 3 1 Spermatogenesis-associated C-terminus Caskin-Pro-rich PF16907.5 KIY73595.1 - 0.024 15.1 0.2 0.049 14.2 0.2 1.5 1 0 0 1 1 1 0 Proline rich region of Caskin proteins PKcGMP_CC PF16808.5 KIY73595.1 - 0.062 13.2 12.3 0.88 9.5 0.0 5.1 5 0 0 5 5 5 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF3584 PF12128.8 KIY73595.1 - 0.11 10.0 20.5 0.12 9.9 10.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Spc7 PF08317.11 KIY73595.1 - 0.25 10.2 26.1 0.12 11.2 15.1 2.4 2 1 0 2 2 2 0 Spc7 kinetochore protein SlyX PF04102.12 KIY73595.1 - 0.26 11.9 0.3 0.26 11.9 0.3 4.4 2 2 2 4 4 4 0 SlyX Fez1 PF06818.15 KIY73595.1 - 0.3 11.5 22.3 0.11 13.0 13.1 2.2 1 1 1 2 2 2 0 Fez1 DUF4107 PF13389.6 KIY73595.1 - 0.33 11.1 2.1 2.2 8.4 2.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF4107) Pox_A_type_inc PF04508.12 KIY73595.1 - 0.41 10.6 13.3 0.088 12.7 3.3 4.5 5 0 0 5 5 4 0 Viral A-type inclusion protein repeat DUF334 PF03904.13 KIY73595.1 - 0.41 10.2 5.0 0.81 9.2 5.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF334) CENP-F_leu_zip PF10473.9 KIY73595.1 - 0.61 10.1 25.6 1.4 8.9 13.2 2.6 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.11 KIY73595.1 - 0.81 9.9 28.8 2.9 8.1 18.0 3.5 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF2312 PF10073.9 KIY73595.1 - 1.8 8.3 10.3 0.87 9.3 0.1 3.4 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2312) TPR_MLP1_2 PF07926.12 KIY73595.1 - 9.1 6.4 28.0 3.2 7.8 11.1 3.2 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Abhydrolase_6 PF12697.7 KIY73596.1 - 2.7e-11 44.5 2.3 3.4e-11 44.2 2.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KIY73596.1 - 2.3e-10 40.5 0.1 3.5e-10 40.0 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIY73596.1 - 2.6e-10 40.0 0.8 1.1e-09 38.0 0.8 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 KIY73596.1 - 0.0012 18.6 0.0 0.48 10.2 0.0 2.5 2 1 0 2 2 2 2 Phospholipase/Carboxylesterase UPF0227 PF05728.12 KIY73596.1 - 0.17 11.8 0.0 0.96 9.4 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) F-box-like PF12937.7 KIY73597.1 - 0.3 11.0 9.3 1.6 8.7 9.3 2.2 1 1 0 1 1 1 0 F-box-like PXA PF02194.15 KIY73598.1 - 3.8e-43 147.6 2.8 4.4e-43 147.4 0.5 2.4 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.12 KIY73598.1 - 1.3e-29 103.0 0.0 7.1e-29 100.7 0.0 2.4 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.24 KIY73598.1 - 1.2e-14 54.2 0.0 5e-14 52.2 0.0 2.1 2 0 0 2 2 2 1 PX domain RGS PF00615.19 KIY73598.1 - 1.8e-08 34.6 1.7 5.3e-08 33.1 1.0 2.3 2 0 0 2 2 2 1 Regulator of G protein signaling domain RR_TM4-6 PF06459.12 KIY73598.1 - 10 5.9 12.3 11 5.7 5.1 2.4 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Pkinase PF00069.25 KIY73599.1 - 0.00063 19.2 0.0 0.0026 17.2 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Choline_kinase PF01633.20 KIY73599.1 - 0.092 12.3 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase_Tyr PF07714.17 KIY73599.1 - 0.13 11.6 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Albumin_I_a PF16720.5 KIY73599.1 - 0.24 11.4 0.6 0.45 10.5 0.6 1.4 1 0 0 1 1 1 0 Albumin I chain a Pkinase PF00069.25 KIY73600.1 - 0.0013 18.2 0.0 0.004 16.6 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY73600.1 - 0.099 11.9 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Choline_kinase PF01633.20 KIY73600.1 - 0.16 11.6 0.0 0.26 10.9 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Cellulase PF00150.18 KIY73602.1 - 1.2e-10 41.3 0.1 1.2e-10 41.3 0.1 1.6 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) MFS_1 PF07690.16 KIY73603.1 - 1.7e-12 46.9 28.2 1.7e-12 46.9 28.2 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 KIY73603.1 - 3.5e-07 30.1 5.7 3.5e-07 30.1 5.7 2.4 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Gcd10p PF04189.13 KIY73604.1 - 5.9e-65 219.3 0.0 8.6e-65 218.8 0.0 1.2 1 0 0 1 1 1 1 Gcd10p family UNC45-central PF11701.8 KIY73605.1 - 3.3e-28 98.6 0.0 1.6e-27 96.3 0.0 2.2 2 0 0 2 2 2 1 Myosin-binding striated muscle assembly central Acyl-CoA_dh_2 PF08028.11 KIY73605.1 - 0.86 9.9 7.5 0.63 10.3 0.2 3.6 2 1 1 3 3 3 0 Acyl-CoA dehydrogenase, C-terminal domain Oxidored_FMN PF00724.20 KIY73606.1 - 4.7e-90 302.3 0.0 5.4e-90 302.1 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Myosin_head PF00063.21 KIY73607.1 - 3.2e-239 795.7 0.4 3.9e-239 795.4 0.4 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 KIY73607.1 - 4.9e-48 163.3 0.0 1e-47 162.3 0.0 1.6 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_2 PF07653.17 KIY73607.1 - 1.4e-08 34.3 0.0 3.5e-08 33.0 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KIY73607.1 - 4.7e-08 32.8 0.2 1.2e-07 31.5 0.2 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KIY73607.1 - 1.5e-07 30.9 1.0 2.8e-07 30.0 1.0 1.5 1 0 0 1 1 1 1 SH3 domain AAA_16 PF13191.6 KIY73607.1 - 0.036 14.4 0.0 0.083 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KIY73607.1 - 0.054 13.8 0.0 0.15 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain Hpr_kinase_C PF07475.12 KIY73607.1 - 0.06 12.9 0.9 9 5.8 0.0 2.4 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain NACHT PF05729.12 KIY73607.1 - 0.16 11.9 0.0 0.37 10.7 0.0 1.6 1 0 0 1 1 1 0 NACHT domain DPBB_1 PF03330.18 KIY73609.1 - 0.086 13.1 0.1 0.14 12.4 0.1 1.5 1 1 0 1 1 1 0 Lytic transglycolase MFS_1 PF07690.16 KIY73612.1 - 1.5e-18 66.9 18.6 2.4e-18 66.2 18.6 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Cpn60_TCP1 PF00118.24 KIY73613.1 - 2.8e-155 517.7 2.2 3.2e-155 517.5 2.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family SNF2_N PF00176.23 KIY73614.1 - 1.2e-71 241.3 0.0 1.6e-71 240.8 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 KIY73614.1 - 5.1e-16 58.4 0.0 1.2e-15 57.2 0.0 1.7 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.31 KIY73614.1 - 3.4e-13 49.9 0.0 1.4e-12 48.0 0.0 2.1 2 0 0 2 2 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.6 KIY73614.1 - 4.8e-08 32.7 12.9 1.4e-07 31.2 8.9 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIY73614.1 - 5.4e-08 32.6 8.6 1e-07 31.7 8.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KIY73614.1 - 1.2e-06 28.4 5.2 3e-06 27.2 4.4 2.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 KIY73614.1 - 3e-06 27.5 7.0 6.2e-06 26.4 7.0 1.6 1 0 0 1 1 1 1 Ring finger domain ResIII PF04851.15 KIY73614.1 - 3.5e-06 27.1 0.0 1.2e-05 25.4 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4_4 PF15227.6 KIY73614.1 - 1.8e-05 24.8 8.3 3.6e-05 23.8 8.3 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 KIY73614.1 - 7.7e-05 22.5 7.2 0.00013 21.8 7.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.29 KIY73614.1 - 0.00014 21.7 0.0 0.00053 19.8 0.0 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_5 PF14634.6 KIY73614.1 - 0.0012 18.8 7.2 0.0021 18.0 7.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-MIZ PF02891.20 KIY73614.1 - 0.0057 16.4 5.6 0.014 15.1 5.6 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 KIY73614.1 - 0.0069 16.2 4.5 0.017 14.9 4.5 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit AAA_34 PF13872.6 KIY73614.1 - 0.0094 14.9 0.0 0.35 9.7 0.0 2.2 2 0 0 2 2 2 1 P-loop containing NTP hydrolase pore-1 DEAD_2 PF06733.15 KIY73614.1 - 0.07 12.7 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 DEAD_2 zf-RING_6 PF14835.6 KIY73614.1 - 0.17 11.8 2.0 0.4 10.6 2.0 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-ANAPC11 PF12861.7 KIY73614.1 - 0.2 11.7 2.3 0.52 10.4 2.3 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KIY73614.1 - 0.28 11.5 4.3 0.56 10.5 3.0 2.2 2 0 0 2 2 2 0 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KIY73614.1 - 2.1 8.3 7.7 35 4.4 8.2 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 KIY73614.1 - 8.4 6.3 7.1 23 4.9 7.1 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain TIM PF00121.18 KIY73615.1 - 9e-90 300.3 0.0 1e-89 300.1 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase CutC PF03932.14 KIY73615.1 - 0.016 14.7 0.1 0.025 14.1 0.1 1.3 1 0 0 1 1 1 0 CutC family DpnD-PcfM PF14207.6 KIY73615.1 - 0.14 12.0 3.0 0.26 11.2 0.1 2.6 3 0 0 3 3 3 0 DpnD/PcfM-like protein CoA_binding PF02629.19 KIY73615.1 - 2.7 8.7 6.4 16 6.3 0.3 2.9 4 0 0 4 4 4 0 CoA binding domain DUF1769 PF08588.10 KIY73616.1 - 1.2e-22 79.8 0.2 2.2e-22 79.0 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) SR-25 PF10500.9 KIY73616.1 - 0.044 13.4 6.3 0.063 12.9 6.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF5401 PF17380.2 KIY73616.1 - 0.4 8.7 2.5 0.51 8.4 2.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) TFIIIC_sub6 PF10419.9 KIY73617.1 - 2.6e-17 62.4 0.0 4.5e-17 61.7 0.0 1.4 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain API5 PF05918.11 KIY73617.1 - 0.055 12.3 3.0 0.068 12.0 3.0 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) ABC_tran PF00005.27 KIY73618.1 - 3.6e-22 79.3 0.0 6.5e-22 78.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KIY73618.1 - 3.6e-07 29.8 0.1 0.016 14.6 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KIY73618.1 - 2e-05 24.5 0.0 5e-05 23.3 0.0 1.6 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KIY73618.1 - 5.1e-05 23.9 0.0 9e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.6 KIY73618.1 - 9.8e-05 22.2 0.0 0.00017 21.4 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KIY73618.1 - 0.00032 20.4 0.0 0.00061 19.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 KIY73618.1 - 0.0058 17.0 0.1 0.02 15.3 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain ABC_ATPase PF09818.9 KIY73618.1 - 0.0081 15.0 0.0 0.44 9.3 0.0 2.2 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_30 PF13604.6 KIY73618.1 - 0.013 15.2 0.0 0.033 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KIY73618.1 - 0.013 15.7 0.0 0.032 14.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KIY73618.1 - 0.019 14.9 0.0 0.034 14.1 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_27 PF13514.6 KIY73618.1 - 0.022 14.3 0.0 0.045 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KIY73618.1 - 0.03 14.6 0.0 0.052 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Ploopntkinase3 PF18751.1 KIY73618.1 - 0.033 14.1 0.0 0.059 13.3 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 FtsK_SpoIIIE PF01580.18 KIY73618.1 - 0.045 13.1 0.0 0.14 11.5 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family G-alpha PF00503.20 KIY73618.1 - 0.1 11.7 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit AAA_33 PF13671.6 KIY73618.1 - 0.12 12.6 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KIY73618.1 - 0.14 11.4 0.0 0.28 10.4 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin MMR_HSR1 PF01926.23 KIY73618.1 - 0.17 12.0 0.0 0.59 10.2 0.0 1.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase TPX2 PF06886.11 KIY73619.1 - 3.3e-09 36.8 21.2 3.3e-09 36.8 21.2 2.0 2 0 0 2 2 2 1 Targeting protein for Xklp2 (TPX2) DPBB_1 PF03330.18 KIY73620.1 - 0.05 13.9 0.2 0.072 13.4 0.2 1.4 1 1 0 1 1 1 0 Lytic transglycolase p450 PF00067.22 KIY73621.1 - 1.1e-70 238.8 0.0 1.3e-70 238.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 C2 PF00168.30 KIY73625.1 - 1.2e-08 35.1 0.0 4.6e-08 33.3 0.0 1.9 2 0 0 2 2 2 1 C2 domain Med20 PF08612.11 KIY73627.1 - 6.2e-05 22.5 0.0 9.8e-05 21.8 0.0 1.4 1 1 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex ORC4_C PF14629.6 KIY73628.1 - 5.2e-29 101.2 0.0 8e-29 100.6 0.0 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 KIY73628.1 - 2.4e-15 57.3 0.2 6.1e-15 56.0 0.2 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KIY73628.1 - 0.023 15.1 0.0 0.065 13.7 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Aspzincin_M35 PF14521.6 KIY73629.1 - 3.1e-45 154.3 6.8 3.1e-45 154.3 6.8 1.8 2 0 0 2 2 2 1 Lysine-specific metallo-endopeptidase HRXXH PF13933.6 KIY73629.1 - 1.7e-05 24.5 3.2 0.0023 17.5 3.2 2.2 1 1 0 1 1 1 1 Putative peptidase family HPTransfase PF10090.9 KIY73629.1 - 0.1 12.4 0.0 0.99 9.2 0.0 2.1 2 0 0 2 2 2 0 Histidine phosphotransferase C-terminal domain RNR_inhib PF08591.10 KIY73630.1 - 4.4e-05 24.7 1.7 9.1e-05 23.7 1.3 1.8 1 1 0 1 1 1 1 Ribonucleotide reductase inhibitor Kelch_4 PF13418.6 KIY73631.1 - 3.7e-23 81.3 12.8 4.6e-06 26.6 0.3 6.1 5 1 0 5 5 5 5 Galactose oxidase, central domain Kelch_3 PF13415.6 KIY73631.1 - 3.4e-14 52.7 21.4 0.00033 20.9 0.8 6.3 5 1 1 6 6 6 5 Galactose oxidase, central domain Kelch_1 PF01344.25 KIY73631.1 - 1e-09 37.8 7.0 0.0037 16.8 0.0 6.1 6 0 0 6 6 6 2 Kelch motif Kelch_6 PF13964.6 KIY73631.1 - 7.3e-08 32.4 10.3 0.039 14.3 0.0 5.8 6 0 0 6 6 6 3 Kelch motif Kelch_5 PF13854.6 KIY73631.1 - 3.8e-07 29.9 11.4 0.93 9.6 0.1 5.1 5 0 0 5 5 5 4 Kelch motif MRAP PF15183.6 KIY73631.1 - 7.9 6.5 6.6 5.7 7.0 0.0 3.1 3 0 0 3 3 3 0 Melanocortin-2 receptor accessory protein family SLAC1 PF03595.17 KIY73632.1 - 2.1e-54 185.0 48.7 2.5e-54 184.7 48.7 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Pkinase PF00069.25 KIY73633.1 - 6.5e-70 235.5 0.0 8.9e-70 235.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY73633.1 - 5.9e-47 160.1 0.0 1e-46 159.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY73633.1 - 5.4e-05 22.6 0.0 0.0012 18.2 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KIY73633.1 - 0.00037 19.4 0.1 0.00087 18.2 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KIY73633.1 - 0.018 14.9 0.0 9.2 6.1 0.0 2.8 2 1 1 3 3 3 0 Phosphotransferase enzyme family Ribosomal_L29 PF00831.23 KIY73634.1 - 1.3e-18 66.7 1.7 1.3e-18 66.7 1.7 2.2 2 1 0 2 2 2 1 Ribosomal L29 protein MRP-L47 PF06984.13 KIY73634.1 - 0.0032 17.5 1.2 0.0032 17.5 1.2 1.9 2 0 0 2 2 2 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) SRP_SPB PF02978.19 KIY73634.1 - 0.12 13.0 2.2 2.3 8.9 0.2 2.2 1 1 1 2 2 2 0 Signal peptide binding domain Snapin_Pallidin PF14712.6 KIY73634.1 - 0.4 11.1 9.1 4.2 7.9 1.5 2.2 1 1 1 2 2 2 0 Snapin/Pallidin His_biosynth PF00977.21 KIY73635.1 - 3e-34 118.5 0.0 3.8e-34 118.1 0.0 1.1 1 0 0 1 1 1 1 Histidine biosynthesis protein Asp PF00026.23 KIY73636.1 - 5.3e-26 91.8 1.9 1.4e-24 87.1 1.9 2.1 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Protocadherin PF08374.11 KIY73636.1 - 0.012 15.6 0.4 0.028 14.4 0.4 1.5 1 0 0 1 1 1 0 Protocadherin gag-asp_proteas PF13975.6 KIY73636.1 - 0.02 15.4 0.0 3.1 8.4 0.0 2.9 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease TMEM154 PF15102.6 KIY73636.1 - 0.025 14.5 0.8 0.055 13.4 0.8 1.5 1 0 0 1 1 1 0 TMEM154 protein family TAXi_N PF14543.6 KIY73636.1 - 0.091 13.0 0.5 12 6.1 0.1 3.2 3 0 0 3 3 3 0 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KIY73636.1 - 0.15 12.8 0.1 2.4 8.8 0.0 2.8 3 0 0 3 3 3 0 Aspartyl protease DUF4689 PF15755.5 KIY73636.1 - 0.64 9.6 6.2 0.38 10.3 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4689) Amidohydro_1 PF01979.20 KIY73638.1 - 3.3e-20 72.7 0.0 2.8e-15 56.5 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 KIY73638.1 - 2.9e-10 40.2 0.0 5.2e-09 36.1 0.0 2.2 2 0 0 2 2 2 1 Amidohydrolase family EMC3_TMCO1 PF01956.16 KIY73639.1 - 3.7e-52 176.5 0.2 4.5e-52 176.2 0.2 1.1 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like V-SNARE PF05008.15 KIY73640.1 - 6.3e-20 71.3 4.8 6.3e-20 71.3 4.8 2.2 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 KIY73640.1 - 1.9e-14 53.7 4.9 1.9e-14 53.7 4.9 2.0 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus LMBR1 PF04791.16 KIY73640.1 - 0.0052 15.7 0.3 0.0063 15.5 0.3 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein Sec20 PF03908.13 KIY73640.1 - 0.011 15.6 0.4 0.024 14.6 0.1 1.7 2 0 0 2 2 2 0 Sec20 YqjK PF13997.6 KIY73640.1 - 0.016 15.4 0.3 0.016 15.4 0.3 2.1 2 0 0 2 2 2 0 YqjK-like protein Laminin_II PF06009.12 KIY73640.1 - 0.074 13.1 1.3 1.4 8.9 0.2 2.2 2 0 0 2 2 2 0 Laminin Domain II Ferlin_C PF16165.5 KIY73640.1 - 0.089 12.7 0.4 0.16 11.9 0.0 1.6 2 0 0 2 2 2 0 Ferlin C-terminus LCIB_C_CA PF18599.1 KIY73640.1 - 0.1 11.8 0.4 0.7 9.2 0.4 1.9 2 0 0 2 2 2 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases Prominin PF05478.11 KIY73640.1 - 0.17 9.8 0.6 5.2 4.9 0.1 2.0 2 0 0 2 2 2 0 Prominin SNARE PF05739.19 KIY73640.1 - 0.25 11.4 6.1 0.39 10.8 0.8 2.6 2 0 0 2 2 2 0 SNARE domain Fib_alpha PF08702.10 KIY73640.1 - 0.52 10.5 4.1 4.7 7.4 1.0 2.8 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DUF883 PF05957.13 KIY73640.1 - 1.1 9.8 8.6 14 6.4 0.1 3.0 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Laminin_I PF06008.14 KIY73640.1 - 1.5 8.5 12.0 3.6 7.2 0.7 2.9 2 1 1 3 3 3 0 Laminin Domain I DUF1640 PF07798.11 KIY73640.1 - 3.1 7.8 7.2 17 5.4 7.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) KCH PF16944.5 KIY73641.1 - 1.1e-87 294.0 13.9 1.3e-87 293.8 13.9 1.1 1 0 0 1 1 1 1 Fungal potassium channel FAM163 PF15069.6 KIY73641.1 - 0.11 12.9 0.0 0.2 12.1 0.0 1.4 1 0 0 1 1 1 0 FAM163 family MMR_HSR1_Xtn PF16897.5 KIY73642.1 - 3e-39 133.3 2.3 1.5e-38 131.1 1.0 2.3 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 KIY73642.1 - 2.3e-24 85.2 0.1 4e-24 84.4 0.1 1.4 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 KIY73642.1 - 5.6e-20 71.5 0.0 1.2e-19 70.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KIY73642.1 - 6.1e-08 32.3 0.2 1.5e-07 31.1 0.1 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B MeaB PF03308.16 KIY73642.1 - 0.018 14.0 1.0 0.032 13.2 0.3 1.8 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Ploopntkinase3 PF18751.1 KIY73642.1 - 0.16 11.9 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 Dynamin_N PF00350.23 KIY73642.1 - 0.26 11.3 3.2 13 5.8 0.0 2.6 2 1 1 3 3 3 0 Dynamin family Rep_fac-A_3 PF08661.11 KIY73643.1 - 2.7e-12 47.0 0.1 3.1e-12 46.8 0.1 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 Fungal_trans PF04082.18 KIY73644.1 - 3.9e-21 75.3 0.2 6.5e-21 74.6 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY73644.1 - 4.3e-05 23.6 10.3 8.1e-05 22.7 10.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SIR2 PF02146.17 KIY73645.1 - 7e-46 156.4 0.0 1e-45 155.9 0.0 1.2 1 0 0 1 1 1 1 Sir2 family Peptidase_M18 PF02127.15 KIY73647.1 - 5.4e-157 523.0 0.0 6.2e-157 522.8 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 KIY73647.1 - 4.2e-05 22.7 0.1 0.0041 16.2 0.2 2.3 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase Brix PF04427.18 KIY73648.1 - 9.7e-33 113.9 0.6 1.4e-32 113.3 0.6 1.3 1 0 0 1 1 1 1 Brix domain WD40 PF00400.32 KIY73649.1 - 5.4e-52 172.6 25.6 1.5e-07 31.9 0.1 12.1 12 0 0 12 12 12 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY73649.1 - 4.4e-20 71.8 8.5 3e-05 24.2 0.0 9.1 5 2 3 9 9 9 6 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 KIY73649.1 - 9.8e-19 67.6 3.2 1.9e-18 66.7 3.2 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family Ge1_WD40 PF16529.5 KIY73649.1 - 7e-11 41.7 8.4 0.0002 20.4 0.2 5.8 2 2 3 5 5 5 4 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KIY73649.1 - 1.9e-07 30.2 5.0 0.099 11.3 0.1 4.5 4 1 0 4 4 4 3 Nucleoporin Nup120/160 WD40_like PF17005.5 KIY73649.1 - 0.00013 21.4 0.2 1.2 8.4 0.1 3.6 3 2 0 4 4 4 2 WD40-like domain ELYS-bb PF16687.5 KIY73649.1 - 0.0041 15.8 0.0 0.087 11.4 0.0 2.2 2 0 0 2 2 2 1 beta-propeller of ELYS nucleoporin eIF2A PF08662.11 KIY73649.1 - 0.16 11.9 0.7 25 4.7 0.0 4.0 2 2 3 5 5 5 0 Eukaryotic translation initiation factor eIF2A Hira PF07569.11 KIY73649.1 - 0.32 10.7 3.8 12 5.6 0.0 3.8 4 0 0 4 4 4 0 TUP1-like enhancer of split AAR2 PF05282.11 KIY73649.1 - 0.38 10.1 2.7 0.35 10.2 0.3 2.0 2 0 0 2 2 2 0 AAR2 protein zf-HIT PF04438.16 KIY73650.1 - 2.2e-07 30.6 8.8 2.2e-07 30.6 8.8 1.7 2 0 0 2 2 2 1 HIT zinc finger zf-B_box PF00643.24 KIY73650.1 - 0.017 15.3 4.7 0.027 14.6 4.7 1.3 1 0 0 1 1 1 0 B-box zinc finger zf-MYND PF01753.18 KIY73650.1 - 4.2 7.5 9.4 7.7 6.7 9.4 1.5 1 0 0 1 1 1 0 MYND finger DUF4604 PF15377.6 KIY73651.1 - 1.9e-29 103.3 13.0 2.2e-29 103.1 13.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) F-box-like PF12937.7 KIY73652.1 - 3e-05 23.8 0.2 7.5e-05 22.6 0.2 1.7 1 0 0 1 1 1 1 F-box-like PHD PF00628.29 KIY73653.1 - 2.5e-08 33.7 0.7 2.5e-08 33.7 0.7 1.7 2 0 0 2 2 2 1 PHD-finger Chromo PF00385.24 KIY73653.1 - 5.8e-05 22.9 0.3 0.00014 21.7 0.3 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DPBB_1 PF03330.18 KIY73654.1 - 3.2e-06 27.3 0.1 8e-06 26.0 0.1 1.8 2 1 0 2 2 2 1 Lytic transglycolase YL1 PF05764.13 KIY73654.1 - 0.0055 16.8 4.9 0.0067 16.6 4.9 1.1 1 0 0 1 1 1 1 YL1 nuclear protein Peptidase_S49_N PF08496.10 KIY73654.1 - 0.0057 16.7 6.5 0.0089 16.1 6.5 1.2 1 0 0 1 1 1 1 Peptidase family S49 N-terminal YqfQ PF14181.6 KIY73654.1 - 0.17 12.1 10.3 0.26 11.5 10.3 1.2 1 0 0 1 1 1 0 YqfQ-like protein NifU PF01106.17 KIY73654.1 - 0.2 11.8 0.5 11 6.2 0.0 2.2 2 0 0 2 2 2 0 NifU-like domain SR-25 PF10500.9 KIY73654.1 - 0.21 11.2 14.2 0.32 10.6 14.2 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Presenilin PF01080.17 KIY73654.1 - 0.48 9.1 1.4 0.59 8.8 1.4 1.1 1 0 0 1 1 1 0 Presenilin CCDC106 PF15794.5 KIY73654.1 - 0.62 9.7 8.4 0.88 9.2 8.4 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 CDC45 PF02724.14 KIY73654.1 - 0.88 7.8 4.7 1.1 7.5 4.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Med19 PF10278.9 KIY73654.1 - 2.7 7.9 15.6 4.1 7.3 15.6 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Fungal_trans PF04082.18 KIY73655.1 - 1.5e-17 63.5 0.4 2.6e-17 62.8 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY73655.1 - 2.1e-05 24.6 11.3 3.8e-05 23.7 11.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KIY73655.1 - 0.00034 19.5 1.5 0.00064 18.6 0.7 1.8 2 1 0 2 2 2 1 Fungal specific transcription factor domain Cys_Met_Meta_PP PF01053.20 KIY73656.1 - 2.8e-50 170.9 0.0 1.1e-49 169.0 0.0 2.0 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Claudin_2 PF13903.6 KIY73657.1 - 0.14 11.9 0.9 0.22 11.2 0.9 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction SNARE_assoc PF09335.11 KIY73658.1 - 7.6e-14 52.2 4.8 7.6e-14 52.2 4.8 2.5 2 1 1 3 3 3 1 SNARE associated Golgi protein Syntaxin-18_N PF10496.9 KIY73659.1 - 1.4e-13 50.9 0.4 8.8e-13 48.3 0.0 2.5 2 1 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.19 KIY73659.1 - 0.057 13.4 0.1 0.2 11.7 0.0 2.0 2 0 0 2 2 2 0 SNARE domain Tfb4 PF03850.14 KIY73659.1 - 0.13 11.7 1.3 0.21 11.1 0.8 1.8 1 1 0 1 1 1 0 Transcription factor Tfb4 AhpC-TSA_2 PF13911.6 KIY73660.1 - 1.5e-12 47.6 0.0 3e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 KIY73660.1 - 2.1e-06 27.7 0.0 4.1e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KIY73660.1 - 0.0036 17.0 0.0 0.0058 16.3 0.0 1.2 1 0 0 1 1 1 1 Redoxin F-box-like PF12937.7 KIY73661.1 - 1.4e-08 34.5 5.5 1.4e-07 31.3 0.4 3.2 3 1 0 3 3 3 2 F-box-like LRR_4 PF12799.7 KIY73661.1 - 0.00078 19.8 8.9 8.2 7.0 0.2 6.6 5 2 1 6 6 6 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KIY73661.1 - 0.045 13.8 0.2 0.95 9.7 0.0 3.4 3 0 0 3 3 3 0 Leucine Rich repeat LRR_8 PF13855.6 KIY73661.1 - 0.1 12.4 13.8 2.6 7.9 0.0 5.6 5 1 0 5 5 5 0 Leucine rich repeat F-box PF00646.33 KIY73661.1 - 2.4 8.1 8.5 0.5 10.3 0.3 3.8 3 1 0 3 3 3 0 F-box domain Ssu72 PF04722.13 KIY73662.1 - 9.7e-84 279.7 0.0 1.2e-83 279.3 0.0 1.1 1 0 0 1 1 1 1 Ssu72-like protein Proteasome PF00227.26 KIY73663.1 - 4.3e-58 195.9 0.0 6.9e-58 195.3 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KIY73663.1 - 8.4e-08 31.8 0.0 3e-07 30.0 0.0 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature GST_N_3 PF13417.6 KIY73664.1 - 9.8e-17 61.1 0.0 1.7e-16 60.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KIY73664.1 - 6e-15 55.3 0.0 1.1e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KIY73664.1 - 7.9e-07 29.3 0.0 1.5e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 KIY73664.1 - 0.00025 21.7 0.0 0.00046 20.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_2 PF13410.6 KIY73664.1 - 0.011 15.8 1.0 0.011 15.8 1.0 2.3 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 KIY73664.1 - 0.048 14.0 0.1 0.077 13.3 0.1 1.3 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein Zn_clus PF00172.18 KIY73665.1 - 7.3e-08 32.4 4.8 1.4e-07 31.6 4.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RPAP1_C PF08620.10 KIY73665.1 - 0.14 12.3 0.0 0.14 12.3 0.0 2.6 3 1 0 3 3 3 0 RPAP1-like, C-terminal Aldedh PF00171.22 KIY73666.1 - 5.6e-177 588.9 0.0 6.3e-177 588.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family COX7C PF02935.16 KIY73667.1 - 1.4e-16 60.5 0.3 1.6e-16 60.3 0.3 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc Ribonuclease_3 PF00636.26 KIY73668.1 - 6.2e-34 116.8 0.0 5.9e-16 59.0 0.0 2.7 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KIY73668.1 - 2.6e-22 79.3 0.0 1.5e-08 34.9 0.1 4.1 4 0 0 4 4 4 3 Ribonuclease-III-like Dicer_dimer PF03368.14 KIY73668.1 - 1.1e-05 25.5 0.0 3.5e-05 23.9 0.0 1.9 1 0 0 1 1 1 1 Dicer dimerisation domain Helicase_C PF00271.31 KIY73668.1 - 3e-05 24.3 0.0 6.3e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PAZ PF02170.22 KIY73668.1 - 6.8e-05 22.7 0.0 0.00013 21.8 0.0 1.4 1 0 0 1 1 1 1 PAZ domain YycC PF14174.6 KIY73668.1 - 0.021 14.6 0.1 0.068 13.0 0.1 1.9 1 0 0 1 1 1 0 YycC-like protein DUF1640 PF07798.11 KIY73669.1 - 1.4e-40 139.2 6.3 1.8e-40 138.9 6.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) DUF2948 PF11164.8 KIY73669.1 - 0.0089 16.0 0.4 0.015 15.3 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2948) DASH_Spc19 PF08287.11 KIY73669.1 - 0.095 12.6 2.9 0.16 11.8 2.9 1.3 1 0 0 1 1 1 0 Spc19 AAA_32 PF13654.6 KIY73669.1 - 0.098 11.4 2.2 0.13 11.0 2.2 1.1 1 0 0 1 1 1 0 AAA domain Zw10 PF06248.13 KIY73669.1 - 0.11 11.1 1.9 0.15 10.6 1.9 1.1 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 Baculo_PEP_C PF04513.12 KIY73669.1 - 0.13 12.3 1.3 0.22 11.5 1.3 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus RGS-like PF09128.11 KIY73669.1 - 0.43 10.3 5.3 4.4 7.0 5.3 2.0 1 1 0 1 1 1 0 Regulator of G protein signalling-like domain Fib_alpha PF08702.10 KIY73669.1 - 2.2 8.5 4.7 7.1 6.8 4.7 1.7 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Glyco_hydro_127 PF07944.12 KIY73670.1 - 6.1e-21 74.5 0.0 5.7e-20 71.3 0.0 2.0 2 0 0 2 2 2 2 Beta-L-arabinofuranosidase, GH127 Mago-bind PF09282.10 KIY73671.1 - 1.1e-14 53.9 1.4 2e-14 53.1 1.4 1.4 1 0 0 1 1 1 1 Mago binding NARP1 PF12569.8 KIY73671.1 - 0.052 12.5 4.8 0.062 12.2 4.8 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 CDC27 PF09507.10 KIY73671.1 - 0.15 11.4 8.2 0.17 11.2 8.2 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Pox_Ag35 PF03286.14 KIY73671.1 - 0.28 10.9 5.2 0.34 10.7 5.2 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein PCI PF01399.27 KIY73672.1 - 2.1e-05 24.9 0.0 4e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 PCI domain TPR_16 PF13432.6 KIY73672.1 - 0.11 13.2 2.7 19 6.0 0.3 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TERB2 PF15101.6 KIY73673.1 - 0.003 17.6 0.0 0.0065 16.6 0.0 1.5 1 0 0 1 1 1 1 Telomere-associated protein TERB2 BRCT_2 PF16589.5 KIY73673.1 - 0.13 12.7 0.0 0.26 11.7 0.0 1.5 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain GST_N PF02798.20 KIY73674.1 - 1.4e-13 51.0 0.0 2.6e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KIY73674.1 - 1.3e-12 47.8 0.0 1.8e-12 47.3 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KIY73674.1 - 4.9e-11 42.7 0.0 9.7e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KIY73674.1 - 4e-08 33.4 0.0 7.6e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KIY73674.1 - 4.2e-08 33.5 0.0 7e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KIY73674.1 - 1.4e-06 28.2 0.1 3.2e-06 27.1 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Stimulus_sens_1 PF13756.6 KIY73677.1 - 0.02 15.4 2.3 0.051 14.2 0.1 2.6 2 1 0 2 2 2 0 Stimulus-sensing domain Nop25 PF09805.9 KIY73677.1 - 2.5 8.6 17.7 0.051 14.0 3.6 3.0 3 0 0 3 3 3 0 Nucleolar protein 12 (25kDa) zinc_ribbon_9 PF14369.6 KIY73678.1 - 4.8 7.5 8.8 0.6 10.4 3.2 2.1 1 1 1 2 2 2 0 zinc-ribbon Auto_anti-p27 PF06677.12 KIY73680.1 - 2.6e-26 91.5 2.8 2.2e-12 46.9 0.3 2.2 2 0 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) BORCS6 PF10157.9 KIY73680.1 - 0.037 14.3 0.4 0.07 13.4 0.0 1.6 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 6 Glyco_hydro_47 PF01532.20 KIY73681.1 - 5e-117 391.6 0.0 7.4e-117 391.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 PA PF02225.22 KIY73681.1 - 0.002 18.1 0.0 0.0037 17.2 0.0 1.4 1 0 0 1 1 1 1 PA domain Pribosyltran PF00156.27 KIY73682.1 - 1.5e-15 57.0 0.0 2.1e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KIY73682.1 - 0.017 14.5 0.0 0.022 14.2 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Ribosomal_S3Ae PF01015.18 KIY73683.1 - 5.3e-94 313.5 2.8 6.5e-94 313.2 2.8 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.16 KIY73683.1 - 0.031 13.9 0.0 0.056 13.0 0.0 1.5 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region LMP PF04778.12 KIY73683.1 - 0.054 13.4 0.1 0.099 12.6 0.1 1.5 1 0 0 1 1 1 0 LMP repeated region Autophagy_act_C PF03987.15 KIY73684.1 - 1.4e-18 67.2 0.1 2.9e-18 66.2 0.1 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Thiolase_N PF00108.23 KIY73685.1 - 1.3e-84 283.6 1.3 1.9e-84 283.1 1.3 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KIY73685.1 - 1.1e-40 138.1 1.2 1.1e-40 138.1 1.2 2.1 2 0 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III_C PF08541.10 KIY73685.1 - 0.03 14.5 0.1 0.084 13.1 0.1 1.8 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ketoacyl-synt PF00109.26 KIY73685.1 - 1.2 8.7 9.9 0.11 12.1 2.7 2.5 2 1 1 3 3 3 0 Beta-ketoacyl synthase, N-terminal domain MFS_1 PF07690.16 KIY73686.1 - 1e-34 120.1 21.2 1.4e-34 119.6 21.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3021 PF11457.8 KIY73686.1 - 0.029 14.7 0.8 0.029 14.7 0.8 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF3021) DUF4551 PF15087.6 KIY73687.1 - 1.7 7.4 6.6 2 7.2 6.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Dynamin_N PF00350.23 KIY73688.1 - 7.8e-07 29.3 0.0 7.8e-07 29.3 0.0 3.4 4 1 0 4 4 4 1 Dynamin family Trypan_PARP PF05887.11 KIY73688.1 - 0.11 12.4 24.1 0.49 10.4 1.3 2.5 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) DUF4211 PF13926.6 KIY73688.1 - 0.18 11.9 1.5 5.3 7.1 0.0 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4211) DUF5308 PF17233.2 KIY73688.1 - 2.5 8.3 12.1 1.2 9.4 0.6 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5308) Jacalin PF01419.17 KIY73689.1 - 0.015 15.2 0.0 0.027 14.4 0.0 1.3 1 0 0 1 1 1 0 Jacalin-like lectin domain AidB_N PF18158.1 KIY73689.1 - 0.035 14.1 0.0 0.12 12.4 0.0 1.8 2 0 0 2 2 2 0 Adaptive response protein AidB N-terminal domain ATP_bind_1 PF03029.17 KIY73691.1 - 1.9e-75 253.7 0.0 2.9e-75 253.2 0.0 1.2 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 KIY73691.1 - 0.0017 18.8 0.0 0.011 16.1 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain CbiA PF01656.23 KIY73691.1 - 0.005 16.9 0.0 0.0071 16.4 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.6 KIY73691.1 - 0.0077 16.5 0.0 0.014 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KIY73691.1 - 0.013 15.0 0.1 0.03 13.8 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_18 PF13238.6 KIY73691.1 - 0.018 15.6 0.0 0.029 14.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KIY73691.1 - 0.019 14.7 0.0 0.026 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KIY73691.1 - 0.025 14.3 0.0 0.042 13.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain CLP1_P PF16575.5 KIY73691.1 - 0.025 14.4 0.0 0.28 10.9 0.0 2.1 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop RNA_helicase PF00910.22 KIY73691.1 - 0.026 14.9 0.0 0.076 13.4 0.0 1.9 2 0 0 2 2 1 0 RNA helicase T2SSE PF00437.20 KIY73691.1 - 0.029 13.4 0.0 0.044 12.8 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein NACHT PF05729.12 KIY73691.1 - 0.03 14.2 0.0 0.049 13.6 0.0 1.3 1 0 0 1 1 1 0 NACHT domain ATPase PF06745.13 KIY73691.1 - 0.033 13.5 0.0 0.051 12.9 0.0 1.3 1 0 0 1 1 1 0 KaiC DUF463 PF04317.12 KIY73691.1 - 0.041 12.8 0.0 0.079 11.9 0.0 1.4 1 0 0 1 1 1 0 YcjX-like family, DUF463 NTPase_1 PF03266.15 KIY73691.1 - 0.058 13.3 0.1 0.18 11.7 0.0 1.8 2 0 0 2 2 2 0 NTPase Ploopntkinase3 PF18751.1 KIY73691.1 - 0.062 13.2 0.0 7.6 6.4 0.0 2.2 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 Sigma54_activat PF00158.26 KIY73691.1 - 0.076 12.7 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_14 PF13173.6 KIY73691.1 - 0.1 12.6 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain ArsA_ATPase PF02374.15 KIY73691.1 - 0.13 11.5 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 Anion-transporting ATPase AAA_30 PF13604.6 KIY73691.1 - 0.17 11.6 0.0 0.27 10.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KIY73691.1 - 0.18 11.3 0.1 0.51 9.9 0.1 1.8 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KIY73691.1 - 0.22 11.7 0.0 0.37 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 KIY73691.1 - 0.22 10.5 0.0 0.4 9.6 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 KIY73691.1 - 0.24 11.3 0.0 4.6 7.1 0.0 2.6 3 0 0 3 3 3 0 RsgA GTPase Vps26 PF03643.15 KIY73692.1 - 9.4e-123 408.6 0.9 1.1e-122 408.4 0.9 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 KIY73692.1 - 0.0029 17.7 1.0 0.24 11.5 0.0 3.3 3 1 1 4 4 4 1 Arrestin (or S-antigen), N-terminal domain PIGA PF08288.12 KIY73693.1 - 5.3e-36 123.1 2.1 9.8e-36 122.2 0.8 2.1 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 KIY73693.1 - 3.5e-25 89.0 4.1 7e-25 88.0 4.1 1.5 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 KIY73693.1 - 1.1e-22 80.3 0.0 1.7e-22 79.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KIY73693.1 - 6.2e-20 72.0 0.0 1.2e-19 71.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KIY73693.1 - 4.3e-12 46.7 0.1 8.1e-12 45.9 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 KIY73693.1 - 0.0019 18.6 0.0 0.0036 17.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 KIY73693.1 - 0.0024 17.9 0.2 0.0041 17.2 0.2 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_transf_5 PF08323.11 KIY73693.1 - 0.094 12.4 0.2 0.43 10.2 0.0 2.0 2 0 0 2 2 2 0 Starch synthase catalytic domain DUF4051 PF13260.6 KIY73694.1 - 0.082 12.6 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) AA_permease_2 PF13520.6 KIY73695.1 - 1.3e-81 274.6 42.0 1.7e-81 274.3 42.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KIY73695.1 - 2.6e-13 49.4 31.4 3.5e-13 49.0 31.4 1.2 1 0 0 1 1 1 1 Amino acid permease adh_short PF00106.25 KIY73696.1 - 2.5e-34 118.4 0.1 3.2e-34 118.1 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIY73696.1 - 2.4e-30 105.8 0.1 3e-30 105.5 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIY73696.1 - 2.3e-05 24.4 0.7 0.00011 22.2 0.7 2.0 1 1 0 1 1 1 1 KR domain SMC_N PF02463.19 KIY73698.1 - 1.7e-65 220.5 0.3 2.8e-65 219.8 0.3 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KIY73698.1 - 2.6e-19 69.6 0.7 6.2e-19 68.4 0.0 2.0 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 KIY73698.1 - 1.6e-12 48.3 0.1 1.6e-12 48.3 0.1 6.5 2 2 0 3 3 3 1 AAA domain AAA_21 PF13304.6 KIY73698.1 - 2.5e-10 40.7 1.8 4.1e-06 26.8 0.2 3.3 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KIY73698.1 - 7.7e-05 22.4 0.1 0.00019 21.1 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ATG16 PF08614.11 KIY73698.1 - 0.00065 20.0 12.0 0.00065 20.0 12.0 6.5 3 2 3 6 6 6 3 Autophagy protein 16 (ATG16) ABC_tran PF00005.27 KIY73698.1 - 0.011 16.3 0.0 0.011 16.3 0.0 6.3 2 2 1 3 3 3 0 ABC transporter DASH_Dam1 PF08653.10 KIY73698.1 - 1.7 8.5 6.5 2.1 8.2 0.4 4.2 4 0 0 4 4 4 0 DASH complex subunit Dam1 EspB_PE PF18625.1 KIY73698.1 - 3.2 8.3 10.0 3.4 8.2 1.5 3.8 3 0 0 3 3 3 0 ESX-1 secreted protein B PE domain NUC130_3NT PF08158.12 KIY73699.1 - 0.025 14.9 0.0 0.048 14.0 0.0 1.5 1 0 0 1 1 1 0 NUC130/3NT domain GCV_T PF01571.21 KIY73700.1 - 0.0003 20.3 0.0 0.00044 19.7 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain ACPS PF01648.20 KIY73701.1 - 2.7e-17 62.9 0.0 3.2e-17 62.7 0.0 1.0 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily WD40 PF00400.32 KIY73702.1 - 9.6e-40 133.9 33.8 3.1e-05 24.6 0.3 11.5 11 0 0 11 11 11 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY73702.1 - 6.5e-15 55.2 6.0 0.13 12.6 0.0 7.8 5 3 4 9 9 9 7 Anaphase-promoting complex subunit 4 WD40 domain Gmad1 PF10647.9 KIY73702.1 - 0.00036 20.4 5.8 0.00061 19.6 0.3 3.5 4 0 0 4 4 4 1 Lipoprotein LpqB beta-propeller domain CBM53 PF16760.5 KIY73702.1 - 0.35 11.5 0.1 0.35 11.5 0.1 2.4 2 0 0 2 2 2 0 Starch/carbohydrate-binding module (family 53) Zn_clus PF00172.18 KIY73703.1 - 9.4e-14 51.3 24.7 9e-08 32.1 5.3 2.6 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain BCDHK_Adom3 PF10436.9 KIY73704.1 - 6.1e-42 143.2 0.1 7.2e-41 139.7 0.0 2.1 2 0 0 2 2 2 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KIY73704.1 - 1.5e-10 41.6 0.0 1.8e-09 38.1 0.0 2.3 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KIY73704.1 - 0.00036 20.4 0.0 0.00061 19.6 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pyridox_oxase_2 PF12766.7 KIY73705.1 - 3.7e-23 82.0 0.0 5.6e-23 81.4 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Putative_PNPOx PF01243.20 KIY73705.1 - 3.3e-06 27.2 0.0 7.4e-06 26.1 0.0 1.6 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DJ-1_PfpI PF01965.24 KIY73706.1 - 1.7e-16 60.5 0.0 1.5e-15 57.4 0.0 2.0 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 KIY73706.1 - 5.8e-05 22.9 0.0 0.00035 20.3 0.0 2.0 1 1 0 1 1 1 1 ThiJ/PfpI family-like Ion_trans PF00520.31 KIY73707.1 - 3.8e-21 75.4 18.7 5.2e-21 75.0 18.7 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 KIY73707.1 - 6.5e-10 38.8 7.9 6.5e-10 38.8 7.9 3.0 2 1 1 3 3 3 1 Ion channel Lig_chan PF00060.26 KIY73707.1 - 0.002 18.0 0.4 0.002 18.0 0.4 1.8 2 0 0 2 2 2 1 Ligand-gated ion channel NIF PF03031.18 KIY73708.1 - 1.2e-50 171.3 0.0 1.7e-50 170.8 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Snf7 PF03357.21 KIY73709.1 - 7.7e-32 110.3 21.7 7.7e-32 110.3 21.7 1.8 1 1 1 2 2 2 1 Snf7 SPOB_a PF14689.6 KIY73709.1 - 0.09 12.5 3.3 1.3 8.8 0.2 2.6 2 0 0 2 2 2 0 Sensor_kinase_SpoOB-type, alpha-helical domain DUF1460 PF07313.12 KIY73709.1 - 0.34 10.3 2.5 0.43 9.9 1.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1460) SBDS_C PF09377.10 KIY73709.1 - 0.44 10.6 7.2 0.66 10.0 6.9 1.4 1 1 0 1 1 1 0 SBDS protein C-terminal domain TRAM_LAG1_CLN8 PF03798.16 KIY73710.1 - 4.7e-41 140.7 23.9 5.9e-41 140.4 23.9 1.1 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.11 KIY73710.1 - 3.1e-08 33.2 0.0 3.1e-08 33.2 0.0 2.2 2 0 0 2 2 2 1 TRAM1-like protein RRM_1 PF00076.22 KIY73711.1 - 1.3e-17 63.4 0.0 1.3e-08 34.5 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SMC_N PF02463.19 KIY73713.1 - 1.8e-62 210.6 0.0 5.2e-62 209.1 0.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KIY73713.1 - 1.6e-27 96.1 0.3 2.3e-26 92.4 0.0 3.0 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KIY73713.1 - 5.5e-18 65.8 0.5 1.7e-06 28.1 0.0 3.9 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KIY73713.1 - 4.6e-10 39.7 6.5 4.6e-10 39.7 6.5 4.5 2 2 0 3 3 3 1 AAA ATPase domain AAA_29 PF13555.6 KIY73713.1 - 1.1e-06 28.2 0.0 2.8e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.6 KIY73713.1 - 0.0026 18.0 0.1 0.018 15.3 0.0 2.5 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit PDGLE PF13190.6 KIY73713.1 - 0.92 9.4 2.5 8.1 6.4 0.1 3.6 2 0 0 2 2 2 0 PDGLE domain MtrG PF04210.13 KIY73713.1 - 1.9 8.4 7.3 26 4.8 0.3 4.3 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G ABC_tran PF00005.27 KIY73714.1 - 2.4e-47 160.9 0.0 3.3e-22 79.5 0.0 2.3 2 0 0 2 2 2 2 ABC transporter ABC2_membrane PF01061.24 KIY73714.1 - 3.7e-46 157.2 27.1 6.6e-29 100.8 15.7 2.4 2 0 0 2 2 2 2 ABC-2 type transporter SMC_N PF02463.19 KIY73714.1 - 4.8e-12 45.8 0.3 7.1e-06 25.6 0.5 3.8 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KIY73714.1 - 3.3e-11 43.6 0.5 0.073 12.9 0.0 4.3 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KIY73714.1 - 1.9e-09 37.7 0.8 4e-05 23.6 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 KIY73714.1 - 3.3e-07 31.0 3.0 0.0038 17.8 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.6 KIY73714.1 - 6.8e-07 28.9 0.7 0.021 14.6 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KIY73714.1 - 3.4e-06 27.6 0.1 0.012 16.0 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain RNA_helicase PF00910.22 KIY73714.1 - 9.2e-06 26.0 0.1 0.15 12.5 0.0 2.8 3 0 0 3 3 2 2 RNA helicase AAA_22 PF13401.6 KIY73714.1 - 5.8e-05 23.4 0.4 0.46 10.8 0.0 3.2 4 1 0 4 4 2 2 AAA domain AAA_5 PF07728.14 KIY73714.1 - 7.7e-05 22.7 0.1 0.3 11.1 0.0 3.4 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) NACHT PF05729.12 KIY73714.1 - 0.00021 21.3 0.1 0.74 9.7 0.0 2.8 3 0 0 3 3 2 2 NACHT domain ATPase_2 PF01637.18 KIY73714.1 - 0.00025 21.1 0.0 0.041 13.8 0.0 2.6 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_28 PF13521.6 KIY73714.1 - 0.00034 20.9 0.1 0.42 10.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain PRK PF00485.18 KIY73714.1 - 0.00036 20.3 0.1 0.16 11.7 0.1 2.3 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_30 PF13604.6 KIY73714.1 - 0.00041 20.1 0.1 1 9.0 0.0 3.0 2 1 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 KIY73714.1 - 0.00045 20.3 0.5 1.2 9.2 0.1 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 KIY73714.1 - 0.00079 19.3 0.0 0.48 10.2 0.0 2.4 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein IstB_IS21 PF01695.17 KIY73714.1 - 0.00097 18.9 0.2 2.8 7.7 0.0 3.1 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_18 PF13238.6 KIY73714.1 - 0.00098 19.7 0.0 2.3 8.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 KIY73714.1 - 0.0015 18.3 0.1 4.5 6.9 0.1 3.2 3 0 0 3 3 3 0 AAA ATPase domain DUF87 PF01935.17 KIY73714.1 - 0.0016 18.6 1.1 0.66 10.0 0.7 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain cobW PF02492.19 KIY73714.1 - 0.002 17.8 0.7 0.72 9.4 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain RuvB_N PF05496.12 KIY73714.1 - 0.0021 17.8 0.1 0.86 9.3 0.0 2.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain FtsK_SpoIIIE PF01580.18 KIY73714.1 - 0.0033 16.8 1.5 1.4 8.3 0.1 3.1 3 0 0 3 3 3 1 FtsK/SpoIIIE family AAA_33 PF13671.6 KIY73714.1 - 0.0039 17.4 0.0 4 7.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KIY73714.1 - 0.0053 16.7 0.1 0.56 10.1 0.0 3.1 3 0 0 3 3 3 1 NTPase KAP_NTPase PF07693.14 KIY73714.1 - 0.0062 15.8 0.0 0.61 9.3 0.0 2.3 2 0 0 2 2 2 1 KAP family P-loop domain AAA_25 PF13481.6 KIY73714.1 - 0.0074 15.9 0.0 1.7 8.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KIY73714.1 - 0.009 16.4 0.0 6.2 7.3 0.0 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KIY73714.1 - 0.0095 15.7 0.1 4.7 6.9 0.1 2.5 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 KIY73714.1 - 0.01 14.9 2.4 1.9 7.5 0.6 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein dNK PF01712.19 KIY73714.1 - 0.017 15.0 0.2 3.7 7.4 0.0 2.4 2 0 0 2 2 2 0 Deoxynucleoside kinase Zeta_toxin PF06414.12 KIY73714.1 - 0.018 14.3 0.0 6.3 6.0 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin Roc PF08477.13 KIY73714.1 - 0.019 15.2 0.1 7 6.9 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Cytidylate_kin PF02224.18 KIY73714.1 - 0.02 14.7 1.0 0.15 11.7 0.0 2.8 3 0 0 3 3 3 0 Cytidylate kinase Rad17 PF03215.15 KIY73714.1 - 0.021 14.7 0.0 7.7 6.4 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain MobB PF03205.14 KIY73714.1 - 0.025 14.5 0.5 0.17 11.8 0.2 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.6 KIY73714.1 - 0.031 14.6 0.0 12 6.2 0.0 3.0 3 1 0 3 3 2 0 AAA domain APS_kinase PF01583.20 KIY73714.1 - 0.038 13.9 1.0 0.74 9.7 0.1 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase Pox_A32 PF04665.12 KIY73714.1 - 0.04 13.4 0.3 1 8.8 0.2 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein Dynamin_N PF00350.23 KIY73714.1 - 0.064 13.3 1.9 7 6.7 0.1 2.5 2 0 0 2 2 2 0 Dynamin family Unstab_antitox PF09720.10 KIY73714.1 - 0.091 12.8 0.1 0.29 11.2 0.1 1.9 1 0 0 1 1 1 0 Putative addiction module component AAA_14 PF13173.6 KIY73714.1 - 0.11 12.5 0.0 5.7 7.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.17 KIY73714.1 - 0.14 11.8 0.0 17 5.0 0.0 2.5 2 0 0 2 2 2 0 Thymidylate kinase SbcCD_C PF13558.6 KIY73714.1 - 0.15 12.4 0.0 36 4.7 0.1 3.1 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit SRP54 PF00448.22 KIY73714.1 - 0.18 11.4 0.1 4.3 6.9 0.0 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Mycoplasma_p37 PF06646.11 KIY73714.1 - 0.19 10.9 0.0 0.35 10.1 0.0 1.3 1 0 0 1 1 1 0 High affinity transport system protein p37 Mob1_phocein PF03637.17 KIY73715.1 - 2.7e-78 261.8 0.0 3.2e-78 261.6 0.0 1.0 1 0 0 1 1 1 1 Mob1/phocein family BTB PF00651.31 KIY73716.1 - 0.00013 22.1 0.0 0.00026 21.2 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain DEAD PF00270.29 KIY73717.1 - 4.6e-43 147.0 0.0 7.1e-43 146.4 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIY73717.1 - 4.4e-26 91.4 0.0 1.1e-25 90.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIY73717.1 - 0.0037 17.3 0.0 0.0061 16.6 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CCDC53 PF10152.9 KIY73717.1 - 0.32 11.4 3.5 0.33 11.4 0.1 2.3 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Fungal_trans PF04082.18 KIY73718.1 - 5.8e-15 55.0 0.0 1e-14 54.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY73718.1 - 6.1e-08 32.7 8.0 1e-07 32.0 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HMG_box PF00505.19 KIY73719.1 - 1.7e-10 41.2 0.9 3.2e-10 40.3 0.9 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KIY73719.1 - 2.2e-05 24.9 0.4 5e-05 23.8 0.4 1.5 1 0 0 1 1 1 1 HMG-box domain Sua5_yciO_yrdC PF01300.18 KIY73720.1 - 3.2e-51 173.4 0.0 7.2e-51 172.2 0.0 1.6 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 KIY73720.1 - 1.7e-30 106.4 0.0 3.4e-30 105.3 0.0 1.5 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding Complex1_LYR_2 PF13233.6 KIY73720.1 - 7.4e-12 45.9 0.1 1.6e-11 44.8 0.1 1.6 1 0 0 1 1 1 1 Complex1_LYR-like RRM_1 PF00076.22 KIY73721.1 - 0.00087 19.1 0.0 0.0018 18.0 0.0 1.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DEAD PF00270.29 KIY73722.1 - 3.8e-19 69.1 0.0 8.5e-19 68.0 0.0 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIY73722.1 - 1.7e-07 31.6 0.0 4.4e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain tRNA-synt_2c PF01411.19 KIY73723.1 - 1e-06 27.6 0.0 1.5e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 KIY73723.1 - 0.0016 18.5 0.0 0.005 16.9 0.0 1.9 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain MFS_1 PF07690.16 KIY73724.1 - 8.5e-36 123.6 31.6 1.3e-35 123.0 31.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily PSGP PF07276.11 KIY73724.1 - 0.27 11.7 1.9 0.75 10.3 1.9 1.8 1 0 0 1 1 1 0 Apopolysialoglycoprotein (PSGP) Mannosidase_ig PF17786.1 KIY73725.1 - 5e-20 71.9 1.8 1.3e-19 70.5 0.3 2.5 3 0 0 3 3 3 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 KIY73725.1 - 5e-10 40.0 0.3 3.8e-09 37.2 0.0 2.5 3 0 0 3 3 3 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.18 KIY73725.1 - 7.5e-05 22.7 0.1 0.00019 21.4 0.1 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Ig_mannosidase PF17753.1 KIY73725.1 - 0.0086 15.8 0.0 0.028 14.2 0.0 1.8 1 0 0 1 1 1 1 Ig-fold domain P2_N PF18628.1 KIY73725.1 - 0.014 15.1 0.1 0.079 12.7 0.0 2.1 2 0 0 2 2 2 0 Viral coat protein P2 N-terminal domain Glyco_hydro_2_C PF02836.17 KIY73725.1 - 0.029 13.5 0.2 0.26 10.4 0.2 2.2 1 1 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Sec7 PF01369.20 KIY73726.1 - 6.8e-73 244.2 1.6 1.1e-72 243.5 0.7 1.9 2 0 0 2 2 2 1 Sec7 domain Sec7_N PF12783.7 KIY73726.1 - 2.1e-42 144.7 2.6 2.1e-42 144.7 2.6 3.6 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 KIY73726.1 - 3.1e-36 123.1 12.1 5.4e-34 115.9 0.2 6.6 7 0 0 7 7 7 2 Domain of unknown function (DUF1981) DCB PF16213.5 KIY73726.1 - 2.7e-22 79.3 4.9 6.1e-21 74.9 0.6 3.6 3 0 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 HEAT PF02985.22 KIY73726.1 - 0.0016 18.6 0.2 9.3 6.8 0.0 4.9 4 0 0 4 4 4 1 HEAT repeat DS PF01916.17 KIY73727.1 - 5.9e-136 452.4 0.0 6.7e-136 452.2 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase 14-3-3 PF00244.20 KIY73728.1 - 2.2e-68 230.1 0.0 2.5e-68 229.9 0.0 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF4736 PF15883.5 KIY73728.1 - 0.063 13.0 0.2 2.7 7.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4736) Aminotran_1_2 PF00155.21 KIY73729.1 - 6.1e-22 78.3 0.0 7.4e-20 71.4 0.0 2.1 1 1 0 1 1 1 1 Aminotransferase class I and II Nsp1_C PF05064.13 KIY73730.1 - 2.5e-29 101.5 0.0 2.8e-28 98.0 0.0 2.2 2 0 0 2 2 2 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.6 KIY73730.1 - 2.9e-17 63.3 98.0 4.7e-06 27.3 20.7 5.0 1 1 4 5 5 5 5 Nucleoporin FG repeat region NPV_P10 PF05531.12 KIY73730.1 - 0.015 15.8 1.4 1.7 9.2 0.0 2.9 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein FlaC_arch PF05377.11 KIY73730.1 - 0.83 10.1 4.2 8.7 6.8 0.2 3.0 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Baculo_PEP_C PF04513.12 KIY73730.1 - 1.1 9.3 3.4 11 6.1 0.4 2.6 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DEAD PF00270.29 KIY73731.1 - 3.3e-50 170.3 0.0 2.4e-49 167.5 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIY73731.1 - 3.6e-25 88.5 0.0 1.2e-24 86.8 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIY73731.1 - 0.0024 17.9 0.0 0.0064 16.5 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 KIY73731.1 - 0.37 10.1 0.0 0.37 10.1 0.0 2.7 3 0 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit Atg14 PF10186.9 KIY73731.1 - 9.7 5.2 11.3 20 4.1 11.3 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 PI31_Prot_N PF11566.8 KIY73732.1 - 2.4e-39 134.8 0.0 3.1e-39 134.4 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.11 KIY73732.1 - 5.9e-14 53.0 13.5 5.9e-14 53.0 13.5 2.8 3 0 0 3 3 3 1 PI31 proteasome regulator DUF4400 PF14348.6 KIY73733.1 - 0.35 10.3 0.8 0.63 9.5 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4400) rRNA_processing PF08524.11 KIY73733.1 - 1 9.4 12.0 1.7 8.6 11.7 1.6 1 1 0 1 1 1 0 rRNA processing Ank_2 PF12796.7 KIY73734.1 - 4.5e-30 104.1 0.3 3.3e-13 50.0 0.1 2.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KIY73734.1 - 1.8e-27 95.1 1.2 2.6e-11 43.5 0.0 3.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KIY73734.1 - 3.6e-22 78.4 1.8 6.4e-13 48.9 0.2 4.0 2 1 2 4 4 4 3 Ankyrin repeats (many copies) FYVE PF01363.21 KIY73734.1 - 8.7e-20 70.6 9.6 8.7e-20 70.6 9.6 2.7 3 0 0 3 3 3 1 FYVE zinc finger Ank_3 PF13606.6 KIY73734.1 - 1.4e-19 68.1 0.5 2.6e-05 24.2 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 KIY73734.1 - 8.8e-15 54.4 2.8 7.4e-05 23.0 0.1 3.5 3 0 0 3 3 3 3 Ankyrin repeat zf-RING_2 PF13639.6 KIY73734.1 - 5.3e-08 33.1 5.3 5.3e-08 33.1 5.3 3.6 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 KIY73734.1 - 1.3e-05 24.9 4.2 1.3e-05 24.9 4.2 3.9 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KIY73734.1 - 0.00037 20.7 2.6 0.00037 20.7 2.6 2.7 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 KIY73734.1 - 0.0061 16.3 5.3 0.0061 16.3 5.3 2.0 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_UBOX PF13445.6 KIY73734.1 - 0.0087 16.1 4.7 0.0087 16.1 4.7 3.3 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KIY73734.1 - 0.014 15.3 4.0 0.014 15.3 4.0 3.3 4 0 0 4 4 3 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 KIY73734.1 - 0.02 15.1 4.4 0.071 13.3 3.1 2.4 2 0 0 2 2 2 0 FANCL C-terminal domain zf-RING_5 PF14634.6 KIY73734.1 - 1.5 8.8 25.8 1.1 9.3 4.8 3.4 3 0 0 3 3 3 0 zinc-RING finger domain TackOD1 PF18551.1 KIY73734.1 - 2.6 7.7 13.5 3.9 7.1 4.5 2.8 3 0 0 3 3 3 0 Thaumarchaeal output domain 1 UPRTase PF14681.6 KIY73735.1 - 9e-66 221.3 0.0 1e-65 221.1 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Methyltransf_8 PF05148.15 KIY73736.1 - 1.1e-65 221.5 0.0 2.8e-65 220.2 0.0 1.6 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_11 PF08241.12 KIY73736.1 - 0.00059 20.4 0.0 0.0029 18.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIY73736.1 - 0.011 16.5 0.0 0.064 14.0 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 KIY73736.1 - 0.063 14.0 0.1 0.18 12.6 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_32 PF13679.6 KIY73736.1 - 0.67 9.9 3.0 3.7 7.5 0.0 2.4 2 1 0 2 2 2 0 Methyltransferase domain Sugar_tr PF00083.24 KIY73737.1 - 3.7e-110 368.9 19.2 4.7e-110 368.5 19.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY73737.1 - 5.4e-24 84.8 36.7 1.6e-17 63.5 8.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KIY73737.1 - 0.0011 17.5 2.2 0.0011 17.5 2.2 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sec63 PF02889.16 KIY73738.1 - 1.1e-75 254.2 0.0 1.6e-75 253.6 0.0 1.3 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.29 KIY73738.1 - 1e-33 116.6 3.2 3.7e-26 91.9 0.5 3.4 4 0 0 4 4 3 2 DEAD/DEAH box helicase ResIII PF04851.15 KIY73738.1 - 9.7e-20 71.3 0.0 2e-10 41.0 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KIY73738.1 - 3.3e-09 37.1 0.2 0.0054 17.0 0.1 3.6 3 0 0 3 3 3 2 AAA domain Helicase_C PF00271.31 KIY73738.1 - 1.4e-07 31.8 0.1 4.8e-06 26.9 0.0 3.4 3 1 0 3 3 2 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 KIY73738.1 - 6.9e-07 29.2 0.4 0.0054 16.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_11 PF13086.6 KIY73738.1 - 8e-05 22.5 0.1 0.021 14.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 KIY73738.1 - 0.00013 22.5 0.0 0.051 14.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KIY73738.1 - 0.00066 20.0 1.0 1.3 9.4 0.2 2.9 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 KIY73738.1 - 0.00091 18.8 0.1 0.35 10.4 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region Helicase_RecD PF05127.14 KIY73738.1 - 0.0015 18.4 0.1 2.2 8.1 0.0 2.6 2 0 0 2 2 2 2 Helicase UvrD-helicase PF00580.21 KIY73738.1 - 0.0018 17.8 0.3 1 8.8 0.1 2.6 2 0 0 2 2 2 2 UvrD/REP helicase N-terminal domain T4SS-DNA_transf PF02534.14 KIY73738.1 - 0.0032 16.4 0.0 0.012 14.5 0.0 1.8 2 0 0 2 2 2 1 Type IV secretory system Conjugative DNA transfer T2SSE PF00437.20 KIY73738.1 - 0.0032 16.6 0.5 0.21 10.6 0.0 2.8 3 0 0 3 3 3 1 Type II/IV secretion system protein IstB_IS21 PF01695.17 KIY73738.1 - 0.0087 15.8 0.0 6.3 6.5 0.0 2.8 2 0 0 2 2 2 1 IstB-like ATP binding protein FtsK_SpoIIIE PF01580.18 KIY73738.1 - 0.03 13.7 0.1 0.28 10.5 0.1 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF87 PF01935.17 KIY73738.1 - 0.052 13.6 0.8 0.26 11.3 0.1 2.4 3 0 0 3 3 3 0 Helicase HerA, central domain Mg_chelatase PF01078.21 KIY73738.1 - 0.087 12.2 0.1 15 4.9 0.1 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 KIY73738.1 - 0.1 12.2 0.2 7.7 6.0 0.0 3.5 4 0 0 4 4 4 0 AAA domain SMC_N PF02463.19 KIY73738.1 - 0.14 11.6 0.6 4.1 6.8 0.0 2.6 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA PF00004.29 KIY73738.1 - 0.19 12.2 3.3 8.8 6.8 0.1 3.4 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) FAD_binding_1 PF00667.20 KIY73739.1 - 3.3e-53 180.5 0.0 5.3e-53 179.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 KIY73739.1 - 1.6e-07 31.9 0.0 3.9e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain POR PF01558.18 KIY73739.1 - 0.001 19.2 0.0 0.0027 17.8 0.0 1.7 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase FAD_binding_6 PF00970.24 KIY73739.1 - 0.11 12.8 0.0 0.41 11.0 0.0 1.9 2 0 0 2 2 2 0 Oxidoreductase FAD-binding domain Glyco_hydro_9 PF00759.19 KIY73740.1 - 8.7e-109 364.7 7.6 1e-108 364.4 7.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Zn_clus PF00172.18 KIY73741.1 - 2e-14 53.4 26.7 1.7e-07 31.2 9.3 2.3 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 KIY73742.1 - 2e-14 53.4 25.9 1.6e-07 31.3 9.5 2.5 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Baculo_IE-1 PF05290.11 KIY73742.1 - 0.14 12.1 0.1 0.14 12.1 0.1 3.0 5 0 0 5 5 5 0 Baculovirus immediate-early protein (IE-0) ubiquitin PF00240.23 KIY73743.1 - 1.8e-07 30.8 0.0 3.5e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 KIY73743.1 - 0.0064 17.0 0.0 0.013 16.1 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain cNMP_binding PF00027.29 KIY73744.1 - 1.7e-32 111.4 2.0 1.1e-14 54.2 0.1 3.2 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.17 KIY73744.1 - 4.7e-07 29.4 0.0 9.6e-07 28.4 0.0 1.5 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit TMP_2 PF06791.13 KIY73745.1 - 0.034 13.8 4.6 0.068 12.8 4.6 1.4 1 0 0 1 1 1 0 Prophage tail length tape measure protein Macoilin PF09726.9 KIY73745.1 - 0.055 12.0 8.8 0.069 11.7 8.8 1.3 1 0 0 1 1 1 0 Macoilin family Adipogenin PF15202.6 KIY73745.1 - 0.077 13.0 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Adipogenin Apt1 PF10351.9 KIY73745.1 - 0.39 9.5 15.8 0.55 9.0 15.8 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Tmemb_cc2 PF10267.9 KIY73745.1 - 5.6 6.0 7.5 8.6 5.4 7.5 1.3 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein PPP4R2 PF09184.11 KIY73745.1 - 6.3 6.3 10.0 10 5.6 10.0 1.2 1 0 0 1 1 1 0 PPP4R2 MFS_1 PF07690.16 KIY73746.1 - 1.6e-33 116.2 18.8 7.8e-33 113.8 19.1 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 KIY73746.1 - 0.00014 21.3 0.6 0.00014 21.3 0.6 2.0 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB PhoPQ_related PF10142.9 KIY73746.1 - 0.37 9.4 4.9 0.25 10.0 3.3 1.4 1 1 1 2 2 2 0 PhoPQ-activated pathogenicity-related protein Ytp1 PF10355.9 KIY73747.1 - 9.7e-105 349.7 1.8 1.5e-104 349.1 1.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 KIY73747.1 - 5e-11 42.3 3.5 6.8e-11 41.9 0.9 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) DUF1218 PF06749.12 KIY73747.1 - 3.8 8.1 12.9 13 6.4 2.5 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF1218) UbiA PF01040.18 KIY73748.1 - 6e-51 173.2 16.7 7.6e-51 172.8 16.7 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Rho_GDI PF02115.17 KIY73749.1 - 2.3e-52 177.6 0.0 2.5e-52 177.5 0.0 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor zf_CCCH_4 PF18345.1 KIY73750.1 - 1.1 9.4 8.5 12 6.2 0.1 4.2 5 0 0 5 5 5 0 Zinc finger domain zf-CCCH_4 PF18044.1 KIY73751.1 - 3.3e-07 30.0 11.3 3.7e-05 23.4 0.1 2.8 3 0 0 3 3 3 2 CCCH-type zinc finger zf-CCCH PF00642.24 KIY73751.1 - 2.3e-05 24.2 10.3 0.0053 16.6 1.8 3.2 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KIY73751.1 - 0.00014 21.8 14.1 0.084 13.0 2.4 3.8 4 0 0 4 4 4 2 Zinc finger domain Torus PF16131.5 KIY73751.1 - 0.023 15.4 10.0 0.65 10.7 0.7 2.7 2 1 1 3 3 3 0 Torus domain EB PF01683.18 KIY73751.1 - 6 7.2 8.0 8 6.8 4.0 2.3 2 0 0 2 2 2 0 EB module CDT1_C PF16679.5 KIY73752.1 - 5.1e-15 55.7 0.6 1.1e-14 54.6 0.2 1.8 2 0 0 2 2 2 1 DNA replication factor Cdt1 C-terminal domain GFO_IDH_MocA PF01408.22 KIY73753.1 - 3.8e-19 69.7 0.0 7.3e-19 68.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KIY73753.1 - 1.9e-08 34.3 0.0 3.6e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 KIY73753.1 - 0.039 14.6 0.0 0.066 13.9 0.0 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KIY73753.1 - 0.09 13.0 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Proteasome PF00227.26 KIY73755.1 - 4.1e-43 147.1 0.0 4.8e-43 146.9 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit CSN8_PSD8_EIF3K PF10075.9 KIY73756.1 - 2.6e-29 102.0 0.0 3.6e-29 101.6 0.0 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 KIY73756.1 - 0.00022 20.7 0.0 0.00031 20.2 0.0 1.1 1 0 0 1 1 1 1 SAC3/GANP family Nup88 PF10168.9 KIY73757.1 - 1.7e-25 89.0 0.0 3e-12 45.2 0.0 2.1 2 0 0 2 2 2 2 Nuclear pore component Nup54 PF13874.6 KIY73757.1 - 3.5e-05 23.9 6.4 5.1e-05 23.4 5.3 1.7 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 FUSC PF04632.12 KIY73757.1 - 0.12 10.8 2.0 0.18 10.3 2.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF3450 PF11932.8 KIY73757.1 - 0.15 11.3 5.5 0.25 10.6 5.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) TPR_MLP1_2 PF07926.12 KIY73757.1 - 0.56 10.3 5.4 1 9.4 5.4 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Proteasome PF00227.26 KIY73758.1 - 5.1e-46 156.6 0.0 6.5e-46 156.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KIY73758.1 - 1.9e-13 49.8 0.1 3.3e-13 49.0 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature MFS_1 PF07690.16 KIY73759.1 - 1.5e-32 112.9 27.8 1.9e-32 112.6 27.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_88 PF07470.13 KIY73760.1 - 2.2e-88 296.7 0.3 2.5e-88 296.5 0.3 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Polyketide_cyc PF03364.20 KIY73761.1 - 1.8e-25 89.7 0.0 2.1e-25 89.4 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 KIY73761.1 - 2.4e-05 24.6 0.0 3e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Chitin_synth_1 PF01644.17 KIY73762.1 - 8.2e-67 224.2 0.1 1.3e-66 223.6 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KIY73762.1 - 5e-30 103.3 0.2 1.2e-29 102.0 0.2 1.7 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KIY73762.1 - 8.5e-24 84.1 0.1 2.2e-18 66.2 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KIY73762.1 - 3.7e-08 33.5 0.0 3.7e-08 33.5 0.0 2.5 1 1 1 2 2 2 1 Glycosyl transferase family group 2 Phasin PF05597.11 KIY73762.1 - 0.092 12.8 0.3 0.26 11.3 0.3 1.6 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF962 PF06127.11 KIY73762.1 - 0.13 12.4 4.0 23 5.1 3.2 3.6 2 1 0 2 2 2 0 Protein of unknown function (DUF962) GST_N_3 PF13417.6 KIY73763.1 - 2.3e-07 31.1 0.0 7.9e-07 29.4 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KIY73763.1 - 0.00011 22.1 1.8 0.00018 21.5 0.1 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KIY73763.1 - 0.0019 18.4 0.0 0.0033 17.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KIY73763.1 - 0.14 12.4 0.0 0.29 11.5 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain NAPRTase PF04095.16 KIY73764.1 - 1.6e-60 204.7 0.2 2.4e-60 204.2 0.2 1.2 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 KIY73764.1 - 1.7e-39 135.1 0.1 2.6e-39 134.4 0.1 1.3 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain RNase_PH PF01138.21 KIY73765.1 - 1.1e-33 116.5 0.3 6.4e-33 114.1 0.1 2.0 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KIY73765.1 - 0.0063 16.5 0.0 0.012 15.7 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 zf-RING_2 PF13639.6 KIY73766.1 - 1.7e-06 28.2 4.6 1.1e-05 25.6 1.5 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 KIY73766.1 - 2.7e-05 23.9 1.8 0.00013 21.8 1.8 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KIY73766.1 - 3.7e-05 23.5 0.7 3.7e-05 23.5 0.7 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIY73766.1 - 6e-05 22.9 0.7 0.0008 19.3 0.5 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KIY73766.1 - 0.00015 21.6 2.7 0.00056 19.7 1.0 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KIY73766.1 - 0.00031 20.9 4.4 0.00087 19.5 4.4 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KIY73766.1 - 0.00049 20.1 0.6 0.0018 18.3 0.6 1.9 1 1 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KIY73766.1 - 0.001 18.9 1.1 0.001 18.9 1.1 1.7 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zinc_ribbon_9 PF14369.6 KIY73766.1 - 0.001 19.2 1.1 0.04 14.2 0.6 2.4 2 0 0 2 2 2 1 zinc-ribbon zf-C3HC4_4 PF15227.6 KIY73766.1 - 0.0012 19.0 1.1 0.0012 19.0 1.1 1.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 KIY73766.1 - 0.083 13.0 1.1 0.37 10.9 0.8 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.8 KIY73766.1 - 0.11 12.3 1.1 0.14 12.0 0.1 1.6 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 KIY73766.1 - 0.13 12.1 4.1 0.1 12.4 1.9 1.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Spo12 PF05032.12 KIY73767.1 - 6.1e-14 51.6 3.5 6.1e-14 51.6 3.5 1.9 2 0 0 2 2 2 1 Spo12 family Ras PF00071.22 KIY73768.1 - 1.3e-42 145.1 0.1 1.5e-42 144.9 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIY73768.1 - 4.1e-14 52.8 0.0 6.8e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIY73768.1 - 4.4e-05 23.0 0.0 5e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KIY73768.1 - 0.00036 20.6 0.0 0.00064 19.8 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KIY73768.1 - 0.00061 19.7 0.1 0.36 10.7 0.0 2.3 1 1 1 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KIY73768.1 - 0.0018 17.9 0.0 0.0052 16.4 0.1 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1_Xtn PF16897.5 KIY73768.1 - 0.028 14.4 0.0 0.039 14.0 0.0 1.4 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain SRPRB PF09439.10 KIY73768.1 - 0.033 13.6 0.0 0.038 13.4 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_14 PF13173.6 KIY73768.1 - 0.16 12.0 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF4646 PF15496.6 KIY73769.1 - 2.1e-08 34.8 0.2 0.00016 22.3 0.2 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF4646) adh_short_C2 PF13561.6 KIY73770.1 - 1.6e-64 217.7 0.5 1.9e-64 217.4 0.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIY73770.1 - 8.6e-47 159.1 1.1 1e-46 158.8 1.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIY73770.1 - 1.6e-06 28.1 1.5 1.9e-06 27.9 0.3 1.5 2 0 0 2 2 2 1 KR domain 3HCDH_N PF02737.18 KIY73770.1 - 0.0016 18.3 0.4 0.01 15.7 0.5 2.0 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 KIY73770.1 - 0.037 14.7 0.0 0.065 14.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain zf-RING_5 PF14634.6 KIY73771.1 - 2.5e-09 36.9 8.1 4.2e-09 36.2 8.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KIY73771.1 - 7.2e-06 26.2 5.3 1.4e-05 25.3 5.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KIY73771.1 - 0.00017 21.4 6.1 0.00032 20.5 6.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KIY73771.1 - 0.00033 20.4 8.0 0.00056 19.7 8.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) HOOK PF05622.12 KIY73771.1 - 0.00067 17.9 6.3 0.00087 17.6 6.3 1.0 1 0 0 1 1 1 1 HOOK protein zf-C3HC4 PF00097.25 KIY73771.1 - 0.00091 19.1 5.7 0.0017 18.2 5.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KIY73771.1 - 0.0023 17.8 5.7 0.0053 16.6 5.7 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Ax_dynein_light PF10211.9 KIY73771.1 - 0.0076 16.2 9.2 0.011 15.7 9.2 1.1 1 0 0 1 1 1 1 Axonemal dynein light chain CENP-Q PF13094.6 KIY73771.1 - 0.0086 16.3 3.3 0.014 15.6 3.3 1.3 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit zf-RING_6 PF14835.6 KIY73771.1 - 0.0091 15.9 2.5 0.02 14.8 2.5 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 KIY73771.1 - 0.0098 16.2 4.4 0.019 15.2 4.4 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain DUF5082 PF16888.5 KIY73771.1 - 0.015 15.6 2.6 0.025 14.9 2.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) DUF4407 PF14362.6 KIY73771.1 - 0.016 14.5 2.4 0.023 14.1 2.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Prok-RING_1 PF14446.6 KIY73771.1 - 0.017 15.0 0.2 0.017 15.0 0.2 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RING_UBOX PF13445.6 KIY73771.1 - 0.018 15.1 0.7 0.018 15.1 0.7 2.5 2 0 0 2 2 2 0 RING-type zinc-finger zf-ribbon_3 PF13248.6 KIY73771.1 - 0.031 13.7 0.1 0.065 12.7 0.1 1.6 1 0 0 1 1 1 0 zinc-ribbon domain zf-RING_4 PF14570.6 KIY73771.1 - 0.041 13.7 3.3 0.08 12.7 3.3 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Exonuc_VII_L PF02601.15 KIY73771.1 - 0.047 13.3 0.5 0.061 12.9 0.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit HR1 PF02185.16 KIY73771.1 - 0.1 12.7 6.2 0.28 11.3 6.2 1.8 1 0 0 1 1 1 0 Hr1 repeat zf-C3HC4_4 PF15227.6 KIY73771.1 - 0.11 12.7 6.8 0.53 10.5 6.0 2.3 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING DUF1272 PF06906.11 KIY73771.1 - 0.18 11.9 6.0 0.42 10.7 6.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) DZR PF12773.7 KIY73771.1 - 0.21 11.7 6.7 0.45 10.6 6.7 1.6 1 0 0 1 1 1 0 Double zinc ribbon Tropomyosin_1 PF12718.7 KIY73771.1 - 0.25 11.5 10.7 0.37 10.9 10.7 1.2 1 0 0 1 1 1 0 Tropomyosin like zf-P11 PF03854.14 KIY73771.1 - 0.35 10.6 5.1 0.72 9.6 5.1 1.5 1 0 0 1 1 1 0 P-11 zinc finger BRE1 PF08647.11 KIY73771.1 - 0.9 9.6 11.2 1.6 8.9 11.2 1.4 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase BST2 PF16716.5 KIY73771.1 - 1.8 9.2 9.3 3.8 8.2 9.3 1.5 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 IBR PF01485.21 KIY73771.1 - 7.2 6.9 7.6 3.1 8.1 3.3 2.2 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain IPK PF03770.16 KIY73773.1 - 4e-51 173.7 0.0 6.4e-51 173.0 0.0 1.3 1 0 0 1 1 1 1 Inositol polyphosphate kinase DUF2407_C PF13373.6 KIY73774.1 - 8.8e-20 71.3 9.2 9.5e-19 68.0 1.6 3.2 3 1 0 3 3 3 2 DUF2407 C-terminal domain DUF2407 PF10302.9 KIY73774.1 - 8.4e-17 61.6 0.0 1.9e-16 60.5 0.0 1.6 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 KIY73774.1 - 3.1e-06 26.8 0.0 5.1e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Forkhead PF00250.18 KIY73775.1 - 1.6e-25 89.1 0.2 2.6e-25 88.5 0.2 1.3 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 KIY73775.1 - 1.6e-06 28.4 0.0 2.7e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 FHA domain BRF1 PF07741.13 KIY73775.1 - 0.0099 16.2 3.2 0.29 11.5 0.6 3.0 3 0 0 3 3 3 1 Brf1-like TBP-binding domain eIF3_subunit PF08597.10 KIY73775.1 - 0.053 13.4 9.7 0.37 10.7 0.1 2.3 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit MAP65_ASE1 PF03999.12 KIY73775.1 - 0.35 9.5 3.5 0.96 8.1 3.5 1.8 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) MTP18 PF10558.9 KIY73776.1 - 4.3e-60 202.6 7.2 1.1e-58 198.0 7.2 2.0 1 1 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) RTP1_C1 PF10363.9 KIY73777.1 - 1.2e-27 96.3 0.0 2e-26 92.4 0.0 2.6 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 KIY73777.1 - 0.047 14.2 4.4 1 9.9 0.1 4.6 4 0 0 4 4 4 0 HEAT-like repeat Sedlin_N PF04628.13 KIY73778.1 - 8.4e-18 64.8 0.0 1.2e-17 64.3 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region SH3_1 PF00018.28 KIY73779.1 - 1.4e-39 133.4 7.7 4.8e-15 54.9 0.2 4.4 4 0 0 4 4 4 3 SH3 domain SH3_9 PF14604.6 KIY73779.1 - 7e-39 131.5 9.0 3.4e-12 46.0 0.3 4.3 4 0 0 4 4 4 3 Variant SH3 domain SHD1 PF03983.12 KIY73779.1 - 9.1e-30 102.3 0.2 3.4e-29 100.4 0.0 2.1 2 0 0 2 2 2 1 SLA1 homology domain 1, SHD1 SH3_2 PF07653.17 KIY73779.1 - 1.8e-23 82.0 0.0 3.9e-08 32.9 0.0 4.4 4 0 0 4 4 4 3 Variant SH3 domain SH3_10 PF17902.1 KIY73779.1 - 2.5e-06 27.5 0.2 0.039 14.0 0.0 3.8 3 1 1 4 4 3 1 SH3 domain hSH3 PF14603.6 KIY73779.1 - 1.7e-05 25.2 0.0 0.019 15.4 0.0 3.1 3 0 0 3 3 3 1 Helically-extended SH3 domain SH3_3 PF08239.11 KIY73779.1 - 2.1e-05 24.7 3.9 0.096 13.0 0.1 3.7 3 0 0 3 3 3 2 Bacterial SH3 domain SAM_4 PF18017.1 KIY73779.1 - 9.5e-05 22.3 0.0 0.00018 21.4 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Borrelia_P83 PF05262.11 KIY73779.1 - 0.052 12.0 9.6 0.097 11.1 9.6 1.4 1 0 0 1 1 1 0 Borrelia P83/100 protein SAM_1 PF00536.30 KIY73779.1 - 0.18 12.3 0.0 0.92 10.0 0.0 2.0 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) Raftlin PF15250.6 KIY73779.1 - 1.1 7.9 4.3 1.8 7.3 4.3 1.2 1 0 0 1 1 1 0 Raftlin CDC45 PF02724.14 KIY73779.1 - 1.6 6.9 15.8 2.5 6.3 15.8 1.1 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 KIY73779.1 - 2.8 7.7 13.5 6.3 6.5 13.5 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SRP-alpha_N PF04086.13 KIY73779.1 - 4.8 7.0 17.5 16 5.3 17.5 1.8 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal CPSF100_C PF13299.6 KIY73779.1 - 6 7.0 7.7 21 5.2 7.7 2.0 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal GTP_EFTU PF00009.27 KIY73780.1 - 4.6e-45 153.5 0.0 6.7e-45 153.0 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KIY73780.1 - 3e-35 120.9 0.1 1.6e-34 118.5 0.1 2.2 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KIY73780.1 - 1.1e-10 41.8 0.2 2.6e-10 40.5 0.2 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 KIY73780.1 - 3.5e-05 23.8 0.3 0.027 14.4 0.2 2.3 1 1 1 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KIY73780.1 - 0.0026 17.8 0.1 0.019 15.0 0.1 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Ndc1_Nup PF09531.10 KIY73780.1 - 1.2 7.7 3.3 1.6 7.3 3.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Esterase_phd PF10503.9 KIY73781.1 - 2.8e-20 72.8 0.8 4e-20 72.2 0.8 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 KIY73781.1 - 1.3e-06 28.1 0.7 1.8e-06 27.6 0.7 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase_phd PF10503.9 KIY73782.1 - 7.6e-22 77.9 0.3 1e-21 77.4 0.3 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 KIY73782.1 - 4.5e-06 26.3 1.2 7.1e-06 25.6 1.2 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 KIY73782.1 - 0.18 11.4 2.5 0.58 9.7 2.5 1.8 1 1 0 1 1 1 0 Putative esterase IF-2B PF01008.17 KIY73783.1 - 3.3e-79 266.0 0.0 4.1e-79 265.7 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family PEP-utilizers PF00391.23 KIY73783.1 - 0.14 11.9 0.2 0.35 10.6 0.2 1.8 1 0 0 1 1 1 0 PEP-utilising enzyme, mobile domain Longin PF13774.6 KIY73784.1 - 1.5e-24 85.8 0.0 2.5e-24 85.1 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 KIY73784.1 - 4.9e-15 55.1 0.0 8e-15 54.4 0.0 1.4 1 0 0 1 1 1 1 Synaptobrevin SLM4 PF16818.5 KIY73784.1 - 0.066 13.2 0.1 0.27 11.2 0.0 2.0 2 0 0 2 2 2 0 Protein SLM4 DUF962 PF06127.11 KIY73785.1 - 2.1e-21 75.8 0.7 5.8e-21 74.4 0.7 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF962) dUTPase PF00692.19 KIY73786.1 - 1e-41 141.6 0.0 1.3e-41 141.3 0.0 1.1 1 0 0 1 1 1 1 dUTPase DUF5615 PF18480.1 KIY73787.1 - 0.17 11.6 0.1 0.35 10.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5615) MAGI_u1 PF16663.5 KIY73787.1 - 2.4 8.3 10.4 5.1 7.3 0.6 3.6 3 0 0 3 3 3 0 Unstructured region on MAGI Peptidase_S24 PF00717.23 KIY73788.1 - 1.9e-07 30.9 0.0 6e-07 29.3 0.0 1.8 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 KIY73788.1 - 6.5e-05 22.7 0.1 0.011 15.5 0.0 2.5 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 CIAPIN1 PF05093.13 KIY73789.1 - 3.4e-32 110.9 3.9 5.5e-32 110.3 3.9 1.3 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DRE2_N PF16803.5 KIY73789.1 - 8.3e-12 45.5 0.0 1.3e-11 44.9 0.0 1.3 1 0 0 1 1 1 1 Fe-S cluster assembly protein DRE2 N-terminus Forkhead PF00250.18 KIY73790.1 - 1.8e-29 101.9 0.0 2.8e-29 101.2 0.0 1.3 1 0 0 1 1 1 1 Forkhead domain DUF3402 PF11882.8 KIY73791.1 - 4.7e-119 398.5 4.3 3.8e-118 395.5 4.3 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.13 KIY73791.1 - 1.2e-74 251.1 0.0 1.8e-74 250.5 0.0 1.2 1 0 0 1 1 1 1 N1221-like protein Cyclin PF08613.11 KIY73792.1 - 0.0066 16.8 0.0 0.013 15.9 0.0 1.4 1 0 0 1 1 1 1 Cyclin ThiF PF00899.21 KIY73793.1 - 3.7e-108 360.5 0.0 3.1e-71 239.6 0.0 2.1 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 KIY73793.1 - 6.9e-88 294.8 0.0 1.2e-87 294.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_FCCH PF16190.5 KIY73793.1 - 1.1e-34 118.4 0.3 2.2e-34 117.5 0.3 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_UFD PF09358.10 KIY73793.1 - 3.4e-33 114.2 1.6 6.9e-33 113.2 1.6 1.6 1 0 0 1 1 1 1 Ubiquitin fold domain E1_4HB PF16191.5 KIY73793.1 - 1.6e-17 63.5 1.1 4.3e-17 62.1 0.5 2.1 2 0 0 2 2 2 1 Ubiquitin-activating enzyme E1 four-helix bundle Cyclin_N PF00134.23 KIY73794.1 - 6.1e-05 22.8 0.2 0.00014 21.6 0.2 1.6 1 1 0 1 1 1 1 Cyclin, N-terminal domain Ycf66_N PF07444.11 KIY73794.1 - 0.11 12.7 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Ycf66 protein N-terminus PTS_2-RNA PF01885.16 KIY73795.1 - 2.6e-59 200.3 0.0 3.5e-59 199.9 0.0 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family DUF1971 PF09313.11 KIY73795.1 - 0.031 14.3 0.0 0.29 11.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1971) EMP24_GP25L PF01105.24 KIY73796.1 - 3.1e-49 167.4 0.3 3.6e-49 167.2 0.3 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Ran_BP1 PF00638.18 KIY73797.1 - 3.8e-50 169.2 0.4 6.3e-50 168.5 0.4 1.3 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.23 KIY73797.1 - 8.3e-06 25.7 0.3 5.1e-05 23.2 0.3 1.9 1 1 0 1 1 1 1 WH1 domain AAA_2 PF07724.14 KIY73798.1 - 2.3e-38 132.0 0.0 4.2e-38 131.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 KIY73798.1 - 3.9e-16 59.7 0.1 1e-15 58.3 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 KIY73798.1 - 6.6e-11 42.1 0.0 1.3e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 KIY73798.1 - 2.8e-07 30.6 0.0 7.1e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KIY73798.1 - 7.6e-06 26.2 0.1 9.8e-05 22.7 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KIY73798.1 - 0.0001 22.7 0.0 0.00019 21.8 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 KIY73798.1 - 0.0013 18.3 0.0 0.0094 15.5 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region AIRS_C PF02769.22 KIY73798.1 - 0.0039 17.3 0.0 0.0086 16.2 0.0 1.6 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain Mg_chelatase PF01078.21 KIY73798.1 - 0.0061 16.0 0.1 0.17 11.3 0.0 2.7 2 1 0 3 3 3 1 Magnesium chelatase, subunit ChlI T2SSE PF00437.20 KIY73798.1 - 0.0084 15.2 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein TsaE PF02367.17 KIY73798.1 - 0.0085 16.1 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 KIY73798.1 - 0.019 14.7 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain MCM PF00493.23 KIY73798.1 - 0.021 14.0 0.3 0.14 11.2 0.3 2.4 1 1 0 1 1 1 0 MCM P-loop domain AAA_14 PF13173.6 KIY73798.1 - 0.023 14.7 0.0 0.039 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KIY73798.1 - 0.024 13.9 0.0 0.034 13.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Sigma54_activat PF00158.26 KIY73798.1 - 0.027 14.2 0.0 0.26 11.0 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain DEAD PF00270.29 KIY73798.1 - 0.031 14.0 0.1 0.1 12.4 0.0 1.9 2 1 1 3 3 2 0 DEAD/DEAH box helicase AAA_33 PF13671.6 KIY73798.1 - 0.034 14.3 0.0 0.068 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 KIY73798.1 - 0.036 13.4 0.0 0.12 11.8 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family NACHT PF05729.12 KIY73798.1 - 0.039 13.9 0.0 0.077 12.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_19 PF13245.6 KIY73798.1 - 0.052 13.9 0.5 0.33 11.3 0.2 2.1 1 1 1 2 2 2 0 AAA domain AAA_29 PF13555.6 KIY73798.1 - 0.068 12.9 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATPase_2 PF01637.18 KIY73798.1 - 0.072 13.0 0.1 2 8.3 0.0 2.2 1 1 0 2 2 2 0 ATPase domain predominantly from Archaea ABC_tran PF00005.27 KIY73798.1 - 0.1 13.1 0.1 0.18 12.3 0.1 1.5 1 1 0 1 1 1 0 ABC transporter IstB_IS21 PF01695.17 KIY73798.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein RuvB_N PF05496.12 KIY73798.1 - 0.13 12.0 1.1 0.83 9.4 0.1 2.7 3 1 0 3 3 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 KIY73798.1 - 0.16 11.9 0.0 3 7.7 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CactinC_cactus PF09732.9 KIY73799.1 - 1.2e-57 193.3 2.9 3e-57 192.0 2.9 1.7 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Cactin_mid PF10312.9 KIY73799.1 - 1.5e-57 194.6 5.1 1.5e-57 194.6 5.1 2.2 1 1 1 2 2 2 1 Conserved mid region of cactin Ribosomal_S8 PF00410.19 KIY73800.1 - 0.00044 20.2 0.0 0.0043 17.0 0.0 2.0 1 1 0 1 1 1 1 Ribosomal protein S8 DUF3449 PF11931.8 KIY73801.1 - 1.3e-73 246.7 3.2 1.2e-72 243.6 1.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 KIY73801.1 - 6e-24 84.4 2.3 7.7e-24 84.0 0.7 2.0 2 0 0 2 2 2 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 zf-C2H2_jaz PF12171.8 KIY73801.1 - 1.8e-07 31.3 0.8 1.8e-07 31.3 0.8 2.8 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KIY73801.1 - 6.5e-07 29.5 7.6 2.8e-06 27.5 1.8 2.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type SF3a60_bindingd PF12108.8 KIY73801.1 - 9.3e-07 28.6 0.0 1.8e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-C2H2_2 PF12756.7 KIY73801.1 - 0.00035 20.8 1.1 0.045 14.1 0.0 2.7 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) P4Ha_N PF08336.11 KIY73801.1 - 0.056 13.4 0.2 0.056 13.4 0.2 2.4 3 0 0 3 3 3 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region zf-DBF PF07535.12 KIY73801.1 - 0.091 12.9 4.2 3.1 8.0 0.1 3.0 2 0 0 2 2 2 0 DBF zinc finger DEAD PF00270.29 KIY73802.1 - 4.6e-41 140.5 0.2 8.6e-41 139.6 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIY73802.1 - 1.1e-31 109.4 0.1 4e-31 107.6 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.6 KIY73802.1 - 0.00052 20.4 0.2 0.012 16.0 0.1 2.3 2 1 0 2 2 2 1 AAA domain ResIII PF04851.15 KIY73802.1 - 0.0007 19.6 0.0 0.0017 18.4 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KIY73802.1 - 0.024 14.4 0.0 0.041 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KIY73802.1 - 0.037 14.3 0.4 0.14 12.5 0.4 1.9 1 1 0 1 1 1 0 AAA domain RRM_1 PF00076.22 KIY73804.1 - 4.3e-19 68.1 1.2 6.2e-19 67.6 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KIY73804.1 - 2.5e-07 30.3 0.0 2.9e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KIY73804.1 - 0.008 16.0 0.1 0.034 14.0 0.0 1.8 2 0 0 2 2 2 1 Occluded RNA-recognition motif SWIM PF04434.17 KIY73805.1 - 9.8e-06 25.1 1.3 1.5e-05 24.5 0.1 1.9 2 0 0 2 2 2 1 SWIM zinc finger UPF0020 PF01170.18 KIY73806.1 - 1.4e-09 37.9 0.1 1.8e-07 31.0 0.1 2.2 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Kinesin PF00225.23 KIY73808.1 - 1.3e-105 353.1 0.6 3.1e-105 351.8 0.0 2.0 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 KIY73808.1 - 5.1e-24 84.9 0.0 2.8e-23 82.5 0.0 2.2 3 0 0 3 3 3 1 Microtubule binding DUF3138 PF11336.8 KIY73808.1 - 0.2 10.2 3.8 0.45 9.1 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) DUF4407 PF14362.6 KIY73808.1 - 0.69 9.2 9.2 2.2 7.6 9.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1192 PF06698.11 KIY73808.1 - 0.97 9.5 13.6 6.3 6.9 1.0 3.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1192) DUF1640 PF07798.11 KIY73808.1 - 1.5 8.8 7.0 0.5 10.4 1.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) DcpS_C PF11969.8 KIY73809.1 - 8.5e-20 71.3 2.5 9.9e-19 67.9 2.5 2.0 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 KIY73809.1 - 1.2e-09 38.7 3.8 8.5e-09 36.1 3.8 2.0 1 1 0 1 1 1 1 HIT domain RNA_pol_Rpb1_5 PF04998.17 KIY73811.1 - 6.1e-86 288.2 0.0 1.4e-85 287.0 0.0 1.6 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KIY73811.1 - 2.6e-63 213.2 0.8 5.1e-63 212.2 0.2 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 KIY73811.1 - 1.2e-38 132.5 0.0 4.1e-38 130.8 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 KIY73811.1 - 1.6e-32 113.1 1.7 2.1e-30 106.1 0.5 3.7 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.17 KIY73811.1 - 1.9e-22 79.2 0.0 7.2e-22 77.4 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Mg-por_mtran_C PF07109.11 KIY73811.1 - 0.15 12.4 0.1 0.57 10.6 0.0 2.0 2 0 0 2 2 2 0 Magnesium-protoporphyrin IX methyltransferase C-terminus Anthrax_toxA PF03497.16 KIY73811.1 - 0.19 11.8 0.9 0.46 10.6 0.9 1.6 1 0 0 1 1 1 0 Anthrax toxin LF subunit BPL_N PF09825.9 KIY73812.1 - 1.3e-43 149.5 0.2 2.5e-27 95.9 0.0 3.0 2 1 1 3 3 3 3 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.19 KIY73812.1 - 1e-21 77.2 0.0 2.5e-21 75.9 0.0 1.7 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.17 KIY73812.1 - 0.0078 16.1 0.1 0.027 14.4 0.1 2.0 1 1 0 1 1 1 1 Biotin protein ligase C terminal domain ABC_transp_aux PF09822.9 KIY73812.1 - 0.028 13.9 0.0 0.15 11.5 0.0 2.0 2 0 0 2 2 2 0 ABC-type uncharacterized transport system HLH PF00010.26 KIY73813.1 - 0.00069 19.5 0.4 0.072 13.1 0.0 2.6 2 0 0 2 2 2 2 Helix-loop-helix DNA-binding domain Ribosomal_S26e PF01283.19 KIY73814.1 - 1.1e-49 167.4 5.8 1.2e-49 167.2 5.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S26e zf_CopZ PF18423.1 KIY73814.1 - 0.017 15.0 0.1 0.034 14.1 0.1 1.5 1 0 0 1 1 1 0 Zinc binding domain CBM_19 PF03427.13 KIY73815.1 - 0.00025 21.0 2.2 0.00025 21.0 2.2 4.2 3 1 2 5 5 5 1 Carbohydrate binding domain (family 19) AfsA PF03756.13 KIY73815.1 - 0.17 11.9 2.6 0.31 11.0 2.6 1.4 1 0 0 1 1 1 0 A-factor biosynthesis hotdog domain MBOAT_2 PF13813.6 KIY73816.1 - 2.3e-18 66.2 6.9 5.2e-18 65.1 6.9 1.6 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Sugar_tr PF00083.24 KIY73817.1 - 4.2e-97 325.8 20.9 4.9e-97 325.6 20.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY73817.1 - 5.3e-19 68.3 35.6 5.6e-15 55.1 14.6 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-PARP PF00645.18 KIY73818.1 - 1.2e-21 77.3 0.4 1.2e-21 77.3 0.4 2.6 3 0 0 3 3 3 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region dsrm PF00035.26 KIY73821.1 - 4.4e-05 24.1 0.0 5.1e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Double-stranded RNA binding motif HLH PF00010.26 KIY73822.1 - 3.1e-11 43.0 0.0 1.1e-10 41.3 0.0 2.0 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF4611 PF15387.6 KIY73822.1 - 0.028 14.6 0.9 0.097 12.9 0.9 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) OppC_N PF12911.7 KIY73822.1 - 0.053 13.5 3.0 51 4.0 0.1 3.7 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C DUF1835 PF08874.10 KIY73822.1 - 0.2 11.9 0.0 0.4 10.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1835) AT_hook PF02178.19 KIY73822.1 - 7.3 6.8 11.8 1.7 8.8 7.0 2.5 2 0 0 2 2 2 0 AT hook motif CAP PF00188.26 KIY73823.1 - 1.1e-17 65.1 6.9 1.3e-17 64.8 6.9 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family RPN7 PF10602.9 KIY73824.1 - 1.9e-37 128.6 0.1 3.1e-37 128.0 0.1 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 KIY73824.1 - 2.7e-15 56.7 0.9 6.6e-15 55.5 0.1 2.1 2 1 1 3 3 3 1 PCI domain TPR_12 PF13424.6 KIY73824.1 - 0.0032 17.7 0.2 0.02 15.2 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 KIY73824.1 - 0.0049 16.8 0.1 0.031 14.3 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF4600 PF15372.6 KIY73824.1 - 0.016 15.6 0.1 0.97 9.9 0.2 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4600) TPR_1 PF00515.28 KIY73824.1 - 0.027 14.3 0.0 0.12 12.2 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 KIY73824.1 - 0.06 13.5 0.0 0.25 11.6 0.0 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat Thioesterase PF00975.20 KIY73825.1 - 5.4e-06 26.7 0.0 1e-05 25.8 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.13 KIY73825.1 - 9.4e-06 25.5 0.4 3.8e-05 23.5 0.4 1.9 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 KIY73825.1 - 3.5e-05 24.5 0.1 5.3e-05 23.9 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.12 KIY73825.1 - 0.00012 21.7 0.1 0.0053 16.3 0.0 2.9 3 0 0 3 3 3 1 Alpha/beta hydrolase of unknown function (DUF900) DUF676 PF05057.14 KIY73825.1 - 0.00019 21.0 0.2 0.00061 19.4 0.2 1.8 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 KIY73825.1 - 0.00021 20.7 0.0 0.00064 19.1 0.0 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Lipase_3 PF01764.25 KIY73825.1 - 0.00074 19.4 0.0 0.0013 18.6 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) LCAT PF02450.15 KIY73825.1 - 0.0011 18.3 0.3 0.012 14.9 0.0 2.1 1 1 1 2 2 2 1 Lecithin:cholesterol acyltransferase DUF2974 PF11187.8 KIY73825.1 - 0.017 14.7 0.0 0.027 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_1 PF00561.20 KIY73825.1 - 0.023 14.4 0.1 0.062 12.9 0.1 1.8 1 1 0 1 1 1 0 alpha/beta hydrolase fold DUF2048 PF09752.9 KIY73825.1 - 0.03 13.4 0.0 0.047 12.8 0.0 1.3 1 0 0 1 1 1 0 Abhydrolase domain containing 18 UPF0227 PF05728.12 KIY73825.1 - 0.097 12.6 0.2 0.17 11.8 0.2 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) DUF915 PF06028.11 KIY73825.1 - 0.13 11.5 1.7 6.7 6.0 0.0 2.6 3 0 0 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF915) Mem_trans PF03547.18 KIY73826.1 - 1.8e-25 89.1 12.5 4.9e-25 87.7 12.5 1.6 1 1 0 1 1 1 1 Membrane transport protein Pro_isomerase PF00160.21 KIY73827.1 - 3.9e-46 157.2 0.1 4.5e-46 157.0 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD F-box-like PF12937.7 KIY73828.1 - 0.0013 18.6 0.0 0.0041 17.0 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KIY73828.1 - 1.3 9.0 3.1 1.9 8.5 0.1 2.8 3 1 0 3 3 3 0 F-box domain adh_short PF00106.25 KIY73829.1 - 1.1e-43 149.0 1.1 1.5e-43 148.5 1.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIY73829.1 - 5.6e-32 111.2 0.2 6.9e-32 110.9 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 KIY73829.1 - 2e-05 24.1 0.0 0.00033 20.1 0.0 2.0 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) KR PF08659.10 KIY73829.1 - 2e-05 24.6 0.2 3.1e-05 23.9 0.2 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KIY73829.1 - 3.4e-05 23.8 0.3 6e-05 23.0 0.3 1.3 1 0 0 1 1 1 1 NAD(P)H-binding ADH_zinc_N PF00107.26 KIY73829.1 - 0.00039 20.4 1.9 0.011 15.7 0.5 2.3 1 1 1 2 2 2 1 Zinc-binding dehydrogenase Epimerase PF01370.21 KIY73829.1 - 0.026 14.0 0.1 0.04 13.4 0.1 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KIY73829.1 - 0.07 12.7 0.3 0.12 11.9 0.3 1.3 1 0 0 1 1 1 0 NmrA-like family RmlD_sub_bind PF04321.17 KIY73829.1 - 0.087 11.9 0.1 0.13 11.3 0.1 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain DNA_pol_lambd_f PF10391.9 KIY73829.1 - 0.092 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda DLIC PF05783.11 KIY73831.1 - 4.3e-41 141.3 5.3 3.5e-32 111.8 0.0 3.2 3 0 0 3 3 3 3 Dynein light intermediate chain (DLIC) Roc PF08477.13 KIY73831.1 - 0.00093 19.4 0.0 0.003 17.8 0.0 1.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 KIY73831.1 - 0.005 17.2 0.0 0.027 14.9 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 KIY73831.1 - 0.1 12.5 0.0 12 5.8 0.1 2.3 2 0 0 2 2 2 0 RsgA GTPase Zeta_toxin PF06414.12 KIY73831.1 - 0.13 11.5 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin IstB_IS21 PF01695.17 KIY73831.1 - 0.14 11.8 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein MMR_HSR1 PF01926.23 KIY73831.1 - 0.15 12.2 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase KTI12 PF08433.10 KIY73831.1 - 0.19 11.1 0.0 0.32 10.4 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 TIP41 PF04176.13 KIY73832.1 - 2.8e-64 215.7 0.0 3.5e-64 215.4 0.0 1.1 1 0 0 1 1 1 1 TIP41-like family TFIID_20kDa PF03847.13 KIY73833.1 - 3e-28 98.1 2.2 8.2e-28 96.7 0.3 2.1 2 0 0 2 2 2 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.23 KIY73833.1 - 9.3e-05 22.6 0.0 0.00049 20.3 0.0 2.1 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KIY73833.1 - 0.013 15.6 0.9 0.026 14.6 0.1 2.0 2 1 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit CENP-T_C PF15511.6 KIY73833.1 - 0.052 13.7 0.8 0.21 11.7 0.0 2.3 2 1 1 3 3 3 0 Centromere kinetochore component CENP-T histone fold DUF5350 PF17299.2 KIY73833.1 - 0.13 12.8 0.7 0.57 10.7 0.3 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5350) adh_short_C2 PF13561.6 KIY73834.1 - 2e-45 155.2 5.9 6.9e-45 153.4 5.9 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KIY73834.1 - 1e-36 126.3 2.8 2.3e-36 125.1 2.8 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KIY73834.1 - 2.3e-09 37.4 2.3 2.9e-09 37.1 0.2 2.0 3 0 0 3 3 3 1 KR domain Eno-Rase_NADH_b PF12242.8 KIY73834.1 - 0.13 12.0 3.7 13 5.7 0.0 3.2 3 0 0 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase PseudoU_synth_2 PF00849.22 KIY73835.1 - 5.5e-27 94.8 0.0 8.2e-27 94.3 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase DUF3741 PF12552.8 KIY73835.1 - 0.11 12.4 0.1 0.23 11.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3741) DUF3632 PF12311.8 KIY73836.1 - 9.2e-42 143.4 0.9 1.3e-41 143.0 0.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) TAFII55_N PF04658.13 KIY73837.1 - 1.3e-56 190.7 0.4 1.3e-56 190.7 0.4 1.9 2 1 0 2 2 2 1 TAFII55 protein conserved region DUF4032 PF13224.6 KIY73837.1 - 0.0062 16.4 0.2 0.013 15.4 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4032) PKcGMP_CC PF16808.5 KIY73837.1 - 1.2 9.0 9.0 2.5 8.0 0.1 3.3 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase SIR4_SID PF16991.5 KIY73837.1 - 2.1 8.4 7.4 1.3 9.0 4.8 2.0 2 0 0 2 2 2 0 Sir4 SID domain BUD22 PF09073.10 KIY73837.1 - 2.3 7.5 28.5 0.015 14.6 18.6 1.9 1 1 1 2 2 2 0 BUD22 SDA1 PF05285.12 KIY73837.1 - 4.1 6.7 28.0 6.8 6.0 28.0 1.3 1 0 0 1 1 1 0 SDA1 DJ-1_PfpI PF01965.24 KIY73838.1 - 8.7e-14 51.7 0.0 1.3e-13 51.1 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.28 KIY73838.1 - 0.03 14.1 0.0 0.14 11.9 0.0 1.9 2 0 0 2 2 2 0 Glutamine amidotransferase class-I Malate_synthase PF01274.22 KIY73839.1 - 7.1e-198 658.1 0.0 8.5e-198 657.9 0.0 1.0 1 0 0 1 1 1 1 Malate synthase SET PF00856.28 KIY73840.1 - 1.6e-08 35.1 0.0 2.5e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 SET domain Cofilin_ADF PF00241.20 KIY73841.1 - 1e-42 144.7 0.9 1.2e-42 144.6 0.9 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Pex14_N PF04695.13 KIY73842.1 - 1.2e-08 35.7 4.3 5.1e-08 33.7 0.4 2.8 1 1 1 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2203 PF09969.9 KIY73842.1 - 0.11 13.2 0.4 4.8 7.9 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) PMC2NT PF08066.12 KIY73844.1 - 0.045 14.4 0.2 0.081 13.6 0.2 1.5 1 1 1 2 2 2 0 PMC2NT (NUC016) domain Pro-kuma_activ PF09286.11 KIY73845.1 - 1.9e-35 122.3 0.0 2.8e-35 121.7 0.0 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KIY73845.1 - 4.9e-06 26.0 0.0 8.8e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Subtilase family Hep_59 PF07052.11 KIY73846.1 - 2.9e-22 79.4 0.1 2.9e-22 79.4 0.1 2.5 2 1 1 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 Nuclease_act PF08133.11 KIY73846.1 - 0.079 13.1 0.2 7.3 7.0 0.1 2.6 2 0 0 2 2 2 0 Anticodon nuclease activator family IL3 PF02059.15 KIY73846.1 - 0.19 11.8 2.0 0.51 10.4 0.2 2.2 2 0 0 2 2 2 0 Interleukin-3 DUF2009 PF09418.10 KIY73847.1 - 2.7e-210 699.2 0.0 3.1e-210 699.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) zf-B_box PF00643.24 KIY73847.1 - 1.1e-06 28.7 4.6 1.9e-06 27.9 4.6 1.4 1 0 0 1 1 1 1 B-box zinc finger CEBP_ZZ PF16366.5 KIY73847.1 - 0.00024 21.3 5.4 0.00051 20.2 5.4 1.5 1 0 0 1 1 1 1 Cytoplasmic polyadenylation element-binding protein ZZ domain ArfGap PF01412.18 KIY73847.1 - 0.067 13.3 1.1 0.19 11.8 0.5 1.9 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf zf-C3HC4_3 PF13920.6 KIY73847.1 - 0.22 11.4 4.7 0.42 10.5 4.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Lipase_GDSL_2 PF13472.6 KIY73848.1 - 2.1e-08 34.8 0.3 2.7e-08 34.4 0.3 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Peptidase_C14 PF00656.22 KIY73849.1 - 3.3e-53 181.2 0.0 4.3e-53 180.8 0.0 1.1 1 0 0 1 1 1 1 Caspase domain CRM1_repeat_2 PF18784.1 KIY73849.1 - 0.18 11.5 0.0 9 6.0 0.0 2.3 2 0 0 2 2 2 0 CRM1 / Exportin repeat 2 Polysacc_lyase PF14099.6 KIY73850.1 - 2.6e-06 27.5 0.0 3.1e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide lyase Xpo1 PF08389.12 KIY73852.1 - 2.2e-10 40.8 0.1 8.1e-05 22.7 0.0 4.6 4 1 0 4 4 4 2 Exportin 1-like protein Importin_rep PF18773.1 KIY73852.1 - 1.3e-06 28.0 1.1 1.8e-06 27.5 0.1 1.9 2 0 0 2 2 2 1 Importin 13 repeat Importin_rep_3 PF18806.1 KIY73852.1 - 1.8e-06 27.9 0.0 7e-06 26.0 0.0 2.1 1 0 0 1 1 1 1 Importin 13 repeat CRM1_C PF08767.11 KIY73852.1 - 0.00039 19.7 0.0 0.00092 18.5 0.0 1.6 1 0 0 1 1 1 1 CRM1 C terminal HEAT_2 PF13646.6 KIY73852.1 - 0.0046 17.3 3.0 2 8.9 0.0 5.4 5 0 0 5 5 5 1 HEAT repeats Katanin_con80 PF13925.6 KIY73852.1 - 0.15 12.1 0.2 15 5.6 0.1 2.9 1 1 1 2 2 2 0 con80 domain of Katanin F-box-like PF12937.7 KIY73853.1 - 0.06 13.2 3.8 0.57 10.1 3.8 2.3 1 1 0 1 1 1 0 F-box-like GNAT_acetyltr_2 PF13718.6 KIY73854.1 - 6e-87 290.8 0.0 1.4e-86 289.5 0.0 1.7 1 0 0 1 1 1 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 KIY73854.1 - 7.3e-67 225.5 0.0 1.2e-66 224.8 0.0 1.3 1 0 0 1 1 1 1 Possible tRNA binding domain Helicase_RecD PF05127.14 KIY73854.1 - 2.3e-61 206.7 0.1 1.1e-60 204.6 0.0 2.2 3 0 0 3 3 3 1 Helicase DUF1726 PF08351.11 KIY73854.1 - 1.1e-32 111.8 0.0 2.7e-32 110.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) Clavanin PF05452.11 KIY73854.1 - 0.074 13.3 0.2 0.16 12.2 0.2 1.5 1 0 0 1 1 1 0 Clavanin DUF742 PF05331.11 KIY73854.1 - 0.082 12.7 0.3 0.35 10.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF742) GHMP_kinases_N PF00288.26 KIY73854.1 - 4.8 7.5 5.4 1.4 9.2 0.3 2.6 3 0 0 3 3 3 0 GHMP kinases N terminal domain PCI PF01399.27 KIY73855.1 - 2e-10 41.1 0.0 4.2e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 PCI domain TPR_2 PF07719.17 KIY73855.1 - 0.02 15.0 0.5 0.2 11.9 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Pribosyltran PF00156.27 KIY73856.1 - 2.3e-16 59.7 0.2 3.1e-16 59.3 0.2 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain MctB PF11382.8 KIY73856.1 - 0.016 14.9 2.7 0.033 13.9 2.7 1.4 1 1 0 1 1 1 0 Copper transport outer membrane protein, MctB Peripla_BP_4 PF13407.6 KIY73856.1 - 0.053 13.1 0.0 0.084 12.4 0.0 1.4 1 0 0 1 1 1 0 Periplasmic binding protein domain UPRTase PF14681.6 KIY73856.1 - 0.078 12.4 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 KIY73856.1 - 0.1 12.1 0.1 0.15 11.5 0.1 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase FAD-oxidase_C PF02913.19 KIY73857.1 - 8.4e-54 182.8 0.0 1.3e-53 182.3 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KIY73857.1 - 2.2e-30 105.2 0.0 4.4e-30 104.2 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain F-box-like PF12937.7 KIY73858.1 - 3.3e-05 23.7 0.1 8.7e-05 22.3 0.1 1.7 1 0 0 1 1 1 1 F-box-like Uds1 PF15456.6 KIY73859.1 - 3.6e-32 111.3 11.9 3.6e-32 111.3 11.9 6.9 4 3 1 6 6 6 2 Up-regulated During Septation 14-3-3 PF00244.20 KIY73860.1 - 3.1e-107 357.1 3.6 3.6e-107 356.9 3.6 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_19 PF14559.6 KIY73860.1 - 0.4 11.2 2.7 0.61 10.6 0.1 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat PGAP1 PF07819.13 KIY73861.1 - 3.5e-51 174.2 0.0 5.5e-51 173.5 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 KIY73861.1 - 8.3e-07 29.8 0.8 8.3e-07 29.8 0.8 2.6 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KIY73861.1 - 0.00023 20.9 0.2 0.0012 18.5 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KIY73861.1 - 0.00047 19.5 0.1 0.001 18.4 0.1 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 BAAT_C PF08840.11 KIY73861.1 - 0.033 14.1 0.0 0.057 13.3 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_5 PF12695.7 KIY73861.1 - 0.057 13.2 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF915 PF06028.11 KIY73861.1 - 0.063 12.6 0.0 0.66 9.3 0.0 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Lipase_3 PF01764.25 KIY73861.1 - 0.13 12.1 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) PLU-1 PF08429.11 KIY73862.1 - 2.3e-51 175.0 0.9 7.8e-51 173.2 0.1 2.2 1 1 1 2 2 2 1 PLU-1-like protein JmjC PF02373.22 KIY73862.1 - 5e-40 136.5 1.4 5e-40 136.5 1.4 1.9 2 0 0 2 2 2 1 JmjC domain, hydroxylase ARID PF01388.21 KIY73862.1 - 5.5e-18 65.4 0.0 1.6e-17 63.9 0.0 1.9 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain JmjN PF02375.17 KIY73862.1 - 8.4e-15 54.4 0.3 2.3e-14 53.1 0.3 1.8 1 0 0 1 1 1 1 jmjN domain PHD PF00628.29 KIY73862.1 - 4e-12 45.8 50.1 2.2e-09 37.1 10.1 5.0 4 1 1 5 5 5 3 PHD-finger zf-C5HC2 PF02928.16 KIY73862.1 - 7.3e-12 45.5 7.5 7.3e-12 45.5 7.5 2.4 2 0 0 2 2 2 1 C5HC2 zinc finger VIR_N PF15912.5 KIY73864.1 - 0.0048 16.5 0.1 0.0048 16.5 0.1 1.8 2 0 0 2 2 2 1 Virilizer, N-terminal ORMDL PF04061.14 KIY73865.1 - 1e-52 177.5 2.5 1.3e-52 177.3 2.5 1.1 1 0 0 1 1 1 1 ORMDL family THF_DHG_CYH PF00763.23 KIY73866.1 - 9.7e-22 77.4 0.0 1.6e-21 76.8 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 KIY73866.1 - 2.4e-16 59.4 0.1 2e-08 33.7 0.0 2.6 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.20 KIY73866.1 - 0.11 12.6 0.2 0.52 10.4 0.0 2.0 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase ATG27 PF09451.10 KIY73867.1 - 2.8e-12 47.1 0.0 4.4e-11 43.1 0.0 2.0 1 1 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.18 KIY73867.1 - 8.4e-10 38.9 0.1 0.00013 22.1 0.0 2.1 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat Man-6-P_recep PF02157.15 KIY73867.1 - 1.3e-08 34.2 0.0 1.8e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Mannose-6-phosphate receptor Herpes_DNAp_acc PF04929.12 KIY73867.1 - 6.2 5.7 10.2 10 5.0 10.2 1.3 1 0 0 1 1 1 0 Herpes DNA replication accessory factor WAC_Acf1_DNA_bd PF10537.9 KIY73868.1 - 1.2e-32 112.4 0.2 3.8e-32 110.8 0.2 1.9 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal WSD PF15613.6 KIY73868.1 - 7.3e-28 97.0 0.3 7.3e-28 97.0 0.3 3.0 3 0 0 3 3 3 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 KIY73868.1 - 1e-15 57.7 0.1 2.6e-15 56.5 0.1 1.6 1 0 0 1 1 1 1 DDT domain WHIM1 PF15612.6 KIY73868.1 - 0.00091 18.7 0.0 0.0022 17.5 0.0 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Cytadhesin_P30 PF07271.11 KIY73868.1 - 0.043 13.4 1.0 0.08 12.5 1.0 1.3 1 0 0 1 1 1 0 Cytadhesin P30/P32 GEP5 PF17053.5 KIY73868.1 - 0.071 12.9 0.3 0.23 11.3 0.3 1.9 1 0 0 1 1 1 0 Genetic interactor of prohibitin 5 CENP-H PF05837.12 KIY73868.1 - 0.12 12.8 16.2 0.21 12.0 0.3 3.5 3 0 0 3 3 3 0 Centromere protein H (CENP-H) F-box-like PF12937.7 KIY73869.1 - 4.1e-08 33.0 0.1 1.6e-07 31.1 0.1 2.1 1 0 0 1 1 1 1 F-box-like PDCD2_C PF04194.13 KIY73870.1 - 9.9e-45 152.7 0.1 9.9e-45 152.7 0.1 1.8 2 0 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain Lar_restr_allev PF14354.6 KIY73870.1 - 1.3 9.4 5.1 13 6.3 5.1 2.5 1 1 0 1 1 1 0 Restriction alleviation protein Lar CorA PF01544.18 KIY73871.1 - 3.2e-44 151.4 0.2 4.8e-44 150.8 0.2 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Baculo_PEP_C PF04513.12 KIY73871.1 - 0.028 14.5 0.4 0.061 13.4 0.4 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus F-box-like PF12937.7 KIY73872.1 - 3.4e-06 26.8 7.5 1.5e-05 24.8 7.5 2.1 1 1 0 1 1 1 1 F-box-like Fmp27_WPPW PF10359.9 KIY73872.1 - 0.011 14.6 0.2 0.015 14.1 0.2 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF3338 PF11819.8 KIY73872.1 - 0.047 13.7 0.1 0.13 12.3 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3338) 5_nucleotid_C PF02872.18 KIY73873.1 - 9e-26 91.0 0.0 1.6e-25 90.2 0.0 1.4 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Acid_PPase PF12689.7 KIY73873.1 - 1.2e-19 70.7 0.0 2.2e-19 70.0 0.0 1.4 1 0 0 1 1 1 1 Acid Phosphatase Metallophos PF00149.28 KIY73873.1 - 2.5e-06 28.1 0.5 7.5e-06 26.6 0.2 1.9 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase AAA PF00004.29 KIY73874.1 - 8e-55 184.9 0.0 9e-39 132.9 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KIY73874.1 - 3.8e-11 43.7 0.3 0.0001 22.8 0.1 3.3 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KIY73874.1 - 1.4e-10 41.6 0.1 0.0002 21.6 0.0 3.8 2 2 1 3 3 3 2 AAA domain AAA_5 PF07728.14 KIY73874.1 - 2.3e-09 37.4 0.0 0.0016 18.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_lid_3 PF17862.1 KIY73874.1 - 1.6e-08 34.2 0.1 4.3e-08 32.8 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain TIP49 PF06068.13 KIY73874.1 - 5.2e-08 32.5 0.1 0.0084 15.3 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_33 PF13671.6 KIY73874.1 - 1.3e-07 31.9 0.0 0.0022 18.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.12 KIY73874.1 - 1.4e-07 31.4 0.1 0.024 14.4 0.1 2.7 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KIY73874.1 - 7.4e-07 29.8 0.0 0.019 15.5 0.0 3.4 3 0 0 3 3 3 2 AAA domain Mg_chelatase PF01078.21 KIY73874.1 - 8.6e-07 28.5 0.1 0.0056 16.1 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 KIY73874.1 - 2.2e-06 28.0 0.0 0.11 12.9 0.0 2.6 2 0 0 2 2 2 2 RNA helicase IstB_IS21 PF01695.17 KIY73874.1 - 2.6e-06 27.3 0.0 0.1 12.3 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_2 PF07724.14 KIY73874.1 - 2.6e-06 27.6 0.2 0.00039 20.6 0.1 2.8 2 1 1 3 3 3 1 AAA domain (Cdc48 subfamily) Sigma54_activat PF00158.26 KIY73874.1 - 6e-06 26.1 0.0 0.05 13.3 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_24 PF13479.6 KIY73874.1 - 9.4e-06 25.5 0.1 0.036 13.8 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_7 PF12775.7 KIY73874.1 - 1.2e-05 24.9 0.5 0.026 14.0 0.0 2.8 3 0 0 3 3 3 2 P-loop containing dynein motor region ABC_tran PF00005.27 KIY73874.1 - 2e-05 25.1 0.0 0.1 13.1 0.1 2.9 2 1 0 2 2 2 2 ABC transporter TsaE PF02367.17 KIY73874.1 - 5.9e-05 23.1 0.0 0.21 11.6 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Parvo_NS1 PF01057.17 KIY73874.1 - 9.3e-05 21.6 0.0 0.4 9.7 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 KIY73874.1 - 0.00011 21.8 0.9 0.64 9.6 0.1 3.5 4 0 0 4 4 3 2 AAA domain AAA_30 PF13604.6 KIY73874.1 - 0.00013 21.8 0.0 0.72 9.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_11 PF13086.6 KIY73874.1 - 0.00015 21.6 0.0 0.58 9.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain ATPase PF06745.13 KIY73874.1 - 0.00019 20.9 0.1 0.023 14.0 0.1 2.5 2 0 0 2 2 2 1 KaiC NACHT PF05729.12 KIY73874.1 - 0.00025 21.0 3.0 0.16 11.9 0.0 3.4 4 0 0 4 4 3 1 NACHT domain AAA_28 PF13521.6 KIY73874.1 - 0.00041 20.6 0.0 0.96 9.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_3 PF07726.11 KIY73874.1 - 0.00051 19.9 0.0 0.16 11.8 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KIY73874.1 - 0.00054 19.2 0.4 0.9 8.7 0.0 2.6 3 0 0 3 3 2 2 NB-ARC domain AAA_14 PF13173.6 KIY73874.1 - 0.001 19.1 0.0 0.24 11.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KIY73874.1 - 0.0013 19.1 0.3 0.73 10.2 0.0 3.2 3 0 0 3 3 3 1 AAA domain DUF2075 PF09848.9 KIY73874.1 - 0.0019 17.5 0.1 0.85 8.8 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 KIY73874.1 - 0.0025 17.3 0.0 1.9 7.9 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein DUF815 PF05673.13 KIY73874.1 - 0.0058 15.8 0.1 0.48 9.5 0.0 2.9 4 0 0 4 4 4 1 Protein of unknown function (DUF815) ATPase_2 PF01637.18 KIY73874.1 - 0.0068 16.3 0.3 24 4.7 0.0 3.8 3 1 1 4 4 4 0 ATPase domain predominantly from Archaea CDC48_N PF02359.18 KIY73874.1 - 0.011 15.9 0.0 0.04 14.1 0.0 2.0 2 0 0 2 2 1 0 Cell division protein 48 (CDC48), N-terminal domain AAA_17 PF13207.6 KIY73874.1 - 0.011 16.2 0.0 3 8.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain Cytidylate_kin PF02224.18 KIY73874.1 - 0.015 15.0 0.1 2.4 7.8 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase Zeta_toxin PF06414.12 KIY73874.1 - 0.016 14.5 0.1 1.1 8.4 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin CDC48_2 PF02933.17 KIY73874.1 - 0.016 15.0 0.1 0.5 10.2 0.0 2.7 2 0 0 2 2 2 0 Cell division protein 48 (CDC48), domain 2 TniB PF05621.11 KIY73874.1 - 0.02 14.3 0.0 3.3 7.1 0.0 3.0 2 1 0 2 2 2 0 Bacterial TniB protein Torsin PF06309.11 KIY73874.1 - 0.024 14.7 0.0 1.2 9.3 0.0 2.5 2 0 0 2 2 2 0 Torsin CPT PF07931.12 KIY73874.1 - 0.033 14.0 0.1 1.2 8.9 0.0 2.9 2 1 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Rad17 PF03215.15 KIY73874.1 - 0.045 13.7 0.0 9.4 6.1 0.0 3.1 3 0 0 3 3 3 0 Rad17 P-loop domain KTI12 PF08433.10 KIY73874.1 - 0.049 13.1 0.1 3.8 6.9 0.0 2.3 2 0 0 2 2 2 0 Chromatin associated protein KTI12 ResIII PF04851.15 KIY73874.1 - 0.053 13.5 0.0 1.4 8.9 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_29 PF13555.6 KIY73874.1 - 0.069 12.9 0.1 6.8 6.5 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain NTPase_1 PF03266.15 KIY73874.1 - 0.1 12.5 0.0 16 5.3 0.0 2.6 2 0 0 2 2 2 0 NTPase Sigma54_activ_2 PF14532.6 KIY73874.1 - 0.11 12.6 0.0 37 4.4 0.0 3.1 3 0 0 3 3 3 0 Sigma-54 interaction domain IPT PF01745.16 KIY73874.1 - 0.19 11.1 0.1 2 7.8 0.0 2.2 2 0 0 2 2 2 0 Isopentenyl transferase DAP3 PF10236.9 KIY73874.1 - 0.2 10.8 0.0 7.2 5.7 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 PPV_E1_C PF00519.17 KIY73874.1 - 0.23 10.2 0.0 15 4.3 0.0 2.1 2 0 0 2 2 2 0 Papillomavirus helicase Glyco_hydro_43 PF04616.14 KIY73876.1 - 1.1e-71 241.5 0.0 1.6e-71 240.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KIY73876.1 - 1.5e-33 116.2 0.2 2.1e-33 115.8 0.2 1.2 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain GTP_EFTU PF00009.27 KIY73877.1 - 1.6e-60 204.0 0.0 2.6e-60 203.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 KIY73877.1 - 8.8e-37 125.6 0.0 3.5e-36 123.6 0.1 2.0 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_II PF14492.6 KIY73877.1 - 4.1e-28 97.3 0.0 8.7e-28 96.2 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 KIY73877.1 - 1.9e-22 79.1 0.0 4.6e-22 77.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KIY73877.1 - 1.3e-10 41.5 0.0 4.3e-10 39.8 0.0 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 KIY73877.1 - 3.2e-06 27.0 0.0 7e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 KIY73877.1 - 0.013 15.6 0.0 0.034 14.2 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase WD40 PF00400.32 KIY73878.1 - 1.4e-19 70.0 20.8 0.00022 22.0 0.4 6.7 6 1 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY73878.1 - 6.7e-07 29.5 3.6 0.05 13.9 0.2 4.2 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KIY73878.1 - 0.00024 20.2 0.7 0.24 10.3 0.1 3.3 2 2 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Helicase_C PF00271.31 KIY73879.1 - 1.9e-12 47.5 0.0 4.3e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SUV3_C PF12513.8 KIY73879.1 - 1.9e-06 27.7 0.0 5.4e-06 26.2 0.0 1.8 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal AAA_22 PF13401.6 KIY73879.1 - 0.056 13.7 0.0 0.25 11.6 0.0 2.1 1 1 0 1 1 1 0 AAA domain zf-MYND PF01753.18 KIY73880.1 - 1.3e-06 28.4 12.3 1.3e-06 28.4 12.3 1.9 2 0 0 2 2 2 1 MYND finger zf-C6H2 PF15801.5 KIY73880.1 - 0.0014 18.9 9.5 0.0035 17.6 9.6 1.7 1 1 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding GPP34 PF05719.11 KIY73880.1 - 0.048 13.7 0.1 0.087 12.8 0.1 1.4 1 0 0 1 1 1 0 Golgi phosphoprotein 3 (GPP34) zinc_ribbon_2 PF13240.6 KIY73880.1 - 1.6 8.5 6.1 4.3 7.2 6.1 1.8 1 0 0 1 1 1 0 zinc-ribbon domain Methyltransf_31 PF13847.6 KIY73881.1 - 1.3e-07 31.5 0.0 2e-07 30.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KIY73881.1 - 6.4e-07 29.1 0.0 1.9e-06 27.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 KIY73881.1 - 2.9e-05 24.7 0.0 8.4e-05 23.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 KIY73881.1 - 0.00082 18.8 0.0 0.0021 17.5 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) PrmC_N PF17827.1 KIY73881.1 - 0.00094 19.7 0.2 0.005 17.4 0.2 2.1 1 1 0 1 1 1 1 PrmC N-terminal domain Methyltransf_10 PF05971.12 KIY73881.1 - 0.001 18.5 0.0 0.0015 17.9 0.0 1.2 1 0 0 1 1 1 1 RNA methyltransferase Methyltransf_23 PF13489.6 KIY73881.1 - 0.0012 18.8 0.0 0.0029 17.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.7 KIY73881.1 - 0.019 14.9 0.0 0.031 14.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 KIY73881.1 - 0.038 14.6 0.0 0.093 13.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain N6_Mtase PF02384.16 KIY73881.1 - 0.075 12.3 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 N-6 DNA Methylase Methyltransf_12 PF08242.12 KIY73881.1 - 0.11 13.3 0.0 0.54 11.0 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Abhydrolase_1 PF00561.20 KIY73882.1 - 4.8e-23 82.1 0.0 1.2e-20 74.2 0.0 2.0 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KIY73882.1 - 3.6e-16 60.4 0.4 4.9e-16 60.0 0.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KIY73882.1 - 2e-07 30.5 0.0 1.6e-06 27.6 0.0 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Ndr PF03096.14 KIY73882.1 - 5e-06 25.4 0.0 6.9e-06 25.0 0.0 1.2 1 0 0 1 1 1 1 Ndr family EHN PF06441.12 KIY73882.1 - 0.16 12.3 0.0 0.33 11.4 0.0 1.5 1 0 0 1 1 1 0 Epoxide hydrolase N terminus Btz PF09405.10 KIY73883.1 - 2e-11 44.3 2.7 2e-11 44.3 2.7 2.4 2 0 0 2 2 2 1 CASC3/Barentsz eIF4AIII binding Collagen_mid PF15984.5 KIY73884.1 - 0.0012 18.6 22.5 0.0016 18.2 22.5 1.1 1 0 0 1 1 1 1 Bacterial collagen, middle region Chlorosome_CsmC PF11098.8 KIY73884.1 - 1.7 8.6 8.5 0.12 12.3 2.1 2.0 1 1 1 2 2 2 0 Chlorosome envelope protein C VPS13_C PF16909.5 KIY73884.1 - 2.8 7.7 5.8 2.8 7.7 2.7 2.0 1 1 1 2 2 2 0 Vacuolar-sorting-associated 13 protein C-terminal Caleosin PF05042.13 KIY73885.1 - 2.6e-10 40.5 0.0 4.1e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 Caleosin related protein Acid_PPase PF12689.7 KIY73886.1 - 9.9e-05 22.2 0.0 0.00022 21.1 0.0 1.6 1 0 0 1 1 1 1 Acid Phosphatase DUF3640 PF12342.8 KIY73887.1 - 0.015 15.0 0.1 0.024 14.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3640) Acid_PPase PF12689.7 KIY73888.1 - 5.3e-32 111.0 1.3 8.7e-32 110.3 1.3 1.3 1 0 0 1 1 1 1 Acid Phosphatase Lin-8 PF03353.15 KIY73888.1 - 0.044 13.3 0.0 0.067 12.7 0.0 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist HAD_2 PF13419.6 KIY73888.1 - 0.1 12.7 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Phage_TAC_9 PF10876.8 KIY73888.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Phage tail assemb.y chaperone protein, TAC Acid_PPase PF12689.7 KIY73890.1 - 9.6e-19 67.8 0.0 1.4e-18 67.3 0.0 1.3 1 0 0 1 1 1 1 Acid Phosphatase Pkinase PF00069.25 KIY73890.1 - 0.017 14.5 0.1 0.32 10.3 0.1 2.2 1 1 0 1 1 1 0 Protein kinase domain Acid_PPase PF12689.7 KIY73891.1 - 5e-27 94.8 0.0 8.7e-27 94.0 0.0 1.4 1 0 0 1 1 1 1 Acid Phosphatase HAD_2 PF13419.6 KIY73891.1 - 0.013 15.6 0.0 0.027 14.5 0.0 1.5 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase RE_Bpu10I PF09549.10 KIY73891.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Bpu10I restriction endonuclease zf-MYND PF01753.18 KIY73892.1 - 4.3e-08 33.1 9.5 4.3e-08 33.1 9.5 2.5 2 1 0 2 2 2 1 MYND finger DUF5571 PF17732.1 KIY73892.1 - 0.023 14.1 0.4 0.054 12.9 0.0 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5571) zf-Mss51 PF13824.6 KIY73892.1 - 0.32 11.1 5.2 0.77 9.9 5.2 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-C6H2 PF15801.5 KIY73892.1 - 3.1 8.2 12.3 1.2 9.5 7.7 2.4 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding ADH_N PF08240.12 KIY73893.1 - 1.5e-26 92.4 1.5 2.4e-26 91.8 1.5 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KIY73893.1 - 2.4e-14 53.4 0.0 3.6e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KIY73893.1 - 7.3e-07 28.9 0.1 1.6e-06 27.8 0.1 1.5 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus adh_short_C2 PF13561.6 KIY73893.1 - 0.068 12.7 0.1 0.095 12.2 0.1 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase ADH_zinc_N_2 PF13602.6 KIY73893.1 - 0.079 14.0 0.0 0.15 13.1 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase IPP-2 PF04979.14 KIY73894.1 - 2.3e-18 67.2 2.5 3.9e-18 66.5 2.5 1.4 1 0 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) STIMATE PF12400.8 KIY73895.1 - 7.3e-38 129.9 6.7 1.1e-37 129.3 6.7 1.3 1 0 0 1 1 1 1 STIMATE family AA_kinase PF00696.28 KIY73896.1 - 1.2e-42 146.1 1.3 2.1e-42 145.4 1.3 1.3 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 KIY73896.1 - 3.8e-11 42.8 0.5 6.2e-05 22.9 0.1 2.8 3 0 0 3 3 3 2 PUA domain PAPA-1 PF04795.12 KIY73897.1 - 4.8e-21 75.4 1.1 4.8e-21 75.4 1.1 2.5 3 0 0 3 3 3 1 PAPA-1-like conserved region Na_H_Exchanger PF00999.21 KIY73898.1 - 1.6e-46 158.9 50.2 2.6e-46 158.2 50.2 1.3 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family ETRAMP PF09716.10 KIY73898.1 - 0.0038 17.3 0.1 0.16 12.1 0.1 2.9 2 0 0 2 2 2 1 Malarial early transcribed membrane protein (ETRAMP) G10 PF01125.17 KIY73899.1 - 1.1e-66 223.1 7.5 1.2e-66 223.0 7.5 1.0 1 0 0 1 1 1 1 G10 protein Metal_resist PF13801.6 KIY73899.1 - 0.077 13.2 0.0 0.11 12.7 0.0 1.1 1 0 0 1 1 1 0 Heavy-metal resistance TB2_DP1_HVA22 PF03134.19 KIY73900.1 - 5.9e-12 45.4 0.0 1e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family MWFE PF15879.5 KIY73902.1 - 1.3e-18 66.9 0.2 1.7e-18 66.5 0.2 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase MWFE subunit DIOX_N PF14226.6 KIY73903.1 - 2.4e-18 67.0 0.2 5.5e-18 65.8 0.0 1.6 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KIY73903.1 - 1.4e-12 48.0 0.0 3.5e-12 46.7 0.0 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ribonuclease_3 PF00636.26 KIY73904.1 - 1.3e-34 118.9 0.0 5.9e-16 59.0 0.0 3.4 3 0 0 3 3 3 2 Ribonuclease III domain Dicer_dimer PF03368.14 KIY73904.1 - 7.3e-16 58.1 0.0 1.9e-15 56.8 0.0 1.7 1 0 0 1 1 1 1 Dicer dimerisation domain Ribonucleas_3_3 PF14622.6 KIY73904.1 - 1.1e-15 57.9 1.2 3.6e-05 23.9 0.1 4.5 4 0 0 4 4 4 4 Ribonuclease-III-like DEAD PF00270.29 KIY73904.1 - 1.4e-15 57.5 0.0 2.7e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KIY73904.1 - 1.2e-13 51.4 0.0 3e-13 50.1 0.0 1.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KIY73904.1 - 3.3e-13 50.0 0.0 8.3e-13 48.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DNA_pol_A_exo1 PF01612.20 KIY73904.1 - 0.075 12.7 0.1 0.18 11.5 0.1 1.6 1 0 0 1 1 1 0 3'-5' exonuclease AAA_22 PF13401.6 KIY73904.1 - 0.078 13.3 0.0 0.31 11.3 0.0 2.0 1 1 0 1 1 1 0 AAA domain DUF3491 PF11996.8 KIY73904.1 - 0.12 10.1 0.2 0.36 8.6 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3491) BPL_LplA_LipB PF03099.19 KIY73905.1 - 6.1e-07 29.4 0.0 1.2e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Lip_prot_lig_C PF10437.9 KIY73905.1 - 0.00029 20.8 0.0 0.00073 19.5 0.0 1.7 1 1 0 1 1 1 1 Bacterial lipoate protein ligase C-terminus Ank_4 PF13637.6 KIY73907.1 - 1.6e-15 57.2 0.1 2.1e-08 34.6 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KIY73907.1 - 2.1e-13 50.6 0.1 6.4e-13 49.1 0.1 1.7 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KIY73907.1 - 6.9e-13 48.5 4.8 1.8e-09 37.7 0.6 2.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIY73907.1 - 1.3e-10 40.5 0.1 4.8e-05 23.5 0.1 3.7 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 KIY73907.1 - 7.1e-09 35.7 1.1 0.00014 22.1 0.3 3.6 4 0 0 4 4 4 2 Ankyrin repeat BCS1_N PF08740.11 KIY73908.1 - 5e-32 111.4 0.1 5e-32 111.4 0.1 1.5 2 0 0 2 2 2 1 BCS1 N terminal AAA PF00004.29 KIY73908.1 - 1.4e-19 70.9 0.0 6.6e-19 68.7 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 KIY73908.1 - 0.00061 19.7 0.2 0.0072 16.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KIY73908.1 - 0.0054 17.1 0.0 0.042 14.2 0.0 2.3 3 0 0 3 3 2 1 RNA helicase AAA_16 PF13191.6 KIY73908.1 - 0.013 15.9 0.0 0.026 14.9 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 KIY73908.1 - 0.015 15.8 0.5 0.059 13.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KIY73908.1 - 0.022 14.7 0.0 0.053 13.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 KIY73908.1 - 0.027 14.0 0.0 0.055 13.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_6 PF12774.7 KIY73908.1 - 0.027 13.5 0.0 0.042 12.8 0.0 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region RuvB_N PF05496.12 KIY73908.1 - 0.062 13.0 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 KIY73908.1 - 0.071 13.0 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain DUF815 PF05673.13 KIY73908.1 - 0.082 12.1 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_22 PF13401.6 KIY73908.1 - 0.099 12.9 0.0 0.4 11.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KIY73908.1 - 0.1 12.8 2.0 0.28 11.4 0.0 2.6 4 0 0 4 4 4 0 AAA domain AAA_24 PF13479.6 KIY73908.1 - 0.16 11.7 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KIY73908.1 - 0.28 11.3 2.4 0.45 10.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain CX9C PF16860.5 KIY73909.1 - 2e-06 27.7 10.3 0.00037 20.5 3.9 2.1 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, CHCH PF06747.13 KIY73909.1 - 0.00018 21.5 4.8 0.00018 21.5 4.8 2.6 3 0 0 3 3 3 2 CHCH domain DB PF01682.19 KIY73909.1 - 0.083 13.2 8.9 2.1 8.7 3.6 2.1 1 1 1 2 2 2 0 DB module NDUF_B7 PF05676.13 KIY73909.1 - 2 8.2 12.4 0.32 10.8 5.6 2.2 1 1 2 3 3 3 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 KIY73909.1 - 8.5 6.5 13.2 9.5 6.3 2.1 2.9 1 1 2 3 3 3 0 Cytochrome c oxidase biogenesis protein Cmc1 like Nitroreductase PF00881.24 KIY73911.1 - 8.6e-23 81.2 0.0 1.2e-22 80.8 0.0 1.2 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 KIY73911.1 - 2.8e-07 30.3 0.0 0.053 13.1 0.0 3.0 2 1 1 3 3 3 3 Putative TM nitroreductase GATA PF00320.27 KIY73912.1 - 1.4e-26 91.7 17.5 7.8e-14 51.0 4.6 2.3 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 KIY73912.1 - 0.0073 15.8 3.0 0.14 11.7 0.1 2.3 2 0 0 2 2 2 1 TFIIB zinc-binding DZR PF12773.7 KIY73912.1 - 0.029 14.4 9.1 1.6 8.8 1.4 3.0 1 1 1 2 2 2 0 Double zinc ribbon NMD3 PF04981.13 KIY73912.1 - 0.085 12.3 4.4 0.21 11.0 0.1 2.1 1 1 1 2 2 2 0 NMD3 family Zn-ribbon_8 PF09723.10 KIY73912.1 - 0.53 10.4 5.6 9 6.5 1.0 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zinc_ribbon_15 PF17032.5 KIY73912.1 - 0.55 11.0 2.9 6.4 7.6 0.2 2.7 1 1 1 2 2 2 0 zinc-ribbon family OrfB_Zn_ribbon PF07282.11 KIY73912.1 - 0.58 10.1 10.4 0.13 12.2 0.8 2.3 2 0 0 2 2 2 0 Putative transposase DNA-binding domain eIF-5_eIF-2B PF01873.17 KIY73912.1 - 0.67 9.8 7.2 4.5 7.2 0.5 2.2 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Cytochrom_c3_2 PF14537.6 KIY73912.1 - 1.1 9.8 6.4 3.1 8.3 2.3 2.2 1 1 1 2 2 2 0 Cytochrome c3 Auto_anti-p27 PF06677.12 KIY73912.1 - 3 8.1 6.6 1.2 9.4 0.6 2.3 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zinc_ribbon_2 PF13240.6 KIY73912.1 - 7.1 6.5 12.1 48 3.9 0.1 4.3 4 0 0 4 4 4 0 zinc-ribbon domain WD40 PF00400.32 KIY73914.1 - 0.0095 16.8 0.0 0.12 13.3 0.0 2.7 2 0 0 2 2 2 1 WD domain, G-beta repeat PBP1_TM PF14812.6 KIY73914.1 - 2.5 8.5 8.0 6.2 7.3 3.4 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal ORC6 PF05460.13 KIY73915.1 - 4.9 6.3 7.2 11 5.1 7.2 1.6 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DUF498 PF04430.14 KIY73916.1 - 3.9e-36 123.4 0.0 5e-36 123.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) RRM_1 PF00076.22 KIY73917.1 - 1.9e-14 53.2 0.0 3.3e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RL PF17797.1 KIY73917.1 - 0.16 12.0 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 RL domain RTA1 PF04479.13 KIY73918.1 - 3.1e-58 196.8 0.8 3.1e-58 196.8 0.8 1.5 2 0 0 2 2 2 1 RTA1 like protein EVE PF01878.18 KIY73920.1 - 1.9e-41 141.5 0.7 3.8e-41 140.5 0.0 1.8 2 1 0 2 2 2 1 EVE domain PI-PLC-X PF00388.19 KIY73921.1 - 2.7e-55 185.9 0.0 6e-55 184.8 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KIY73921.1 - 2.9e-37 127.5 1.3 4e-37 127.1 0.0 1.9 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 KIY73921.1 - 1.3e-08 35.0 0.0 3.7e-08 33.6 0.0 1.8 1 0 0 1 1 1 1 C2 domain GDPD PF03009.17 KIY73921.1 - 0.0042 16.9 0.2 0.011 15.5 0.0 1.7 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family EF-hand_1 PF00036.32 KIY73921.1 - 0.0066 15.9 0.0 0.41 10.3 0.0 2.7 2 0 0 2 2 2 1 EF hand PH_14 PF17787.1 KIY73921.1 - 0.016 15.1 0.1 0.03 14.2 0.1 1.5 1 0 0 1 1 1 0 PH domain Dehydrin PF00257.19 KIY73921.1 - 0.034 14.7 0.6 0.064 13.8 0.6 1.3 1 0 0 1 1 1 0 Dehydrin EF-hand_10 PF14788.6 KIY73921.1 - 0.045 13.6 0.0 1.5 8.7 0.0 2.5 1 1 1 2 2 2 0 EF hand EF-hand_like PF09279.11 KIY73921.1 - 0.069 13.6 0.1 0.31 11.6 0.1 2.1 1 1 0 1 1 1 0 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_7 PF13499.6 KIY73921.1 - 0.14 12.6 0.1 0.53 10.8 0.1 1.9 1 1 1 2 2 2 0 EF-hand domain pair MAS20 PF02064.15 KIY73922.1 - 2.5e-37 127.9 0.2 4.3e-37 127.1 0.2 1.4 1 0 0 1 1 1 1 MAS20 protein import receptor SET PF00856.28 KIY73922.1 - 1.6e-07 31.9 0.0 5.3e-07 30.2 0.0 2.1 2 1 0 2 2 2 1 SET domain zf-MYND PF01753.18 KIY73922.1 - 0.048 13.8 0.2 0.048 13.8 0.2 1.8 2 0 0 2 2 2 0 MYND finger SAF PF08666.12 KIY73922.1 - 0.049 14.3 0.1 15 6.3 0.0 2.7 2 0 0 2 2 2 0 SAF domain SMK-1 PF04802.15 KIY73923.1 - 3.3e-75 252.2 0.2 6.7e-75 251.1 0.2 1.6 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 SKG6 PF08693.10 KIY73926.1 - 0.00019 20.8 1.4 0.00043 19.6 1.4 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4381 PF14316.6 KIY73926.1 - 0.018 15.3 0.1 0.036 14.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Rax2 PF12768.7 KIY73926.1 - 0.021 14.3 0.0 0.054 13.0 0.0 1.5 1 1 0 1 1 1 0 Cortical protein marker for cell polarity DUF5305 PF17231.2 KIY73926.1 - 0.06 12.7 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) tRNA_m1G_MT PF01746.21 KIY73927.1 - 2.2e-26 92.7 0.1 3.8e-26 92.0 0.1 1.4 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase Ribosomal_L30_N PF08079.12 KIY73927.1 - 1 9.7 16.6 2 8.7 16.6 1.5 1 0 0 1 1 1 0 Ribosomal L30 N-terminal domain WD40 PF00400.32 KIY73928.1 - 1.3e-29 101.8 4.4 0.00019 22.2 0.0 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY73928.1 - 6.5e-14 52.0 0.0 0.00018 21.7 0.0 4.9 3 3 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KIY73928.1 - 0.0057 16.0 0.0 0.34 10.2 0.0 2.5 3 0 0 3 3 3 1 WD40-like domain Frtz PF11768.8 KIY73928.1 - 0.037 12.3 0.0 0.88 7.8 0.0 2.1 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Ge1_WD40 PF16529.5 KIY73928.1 - 0.15 11.0 0.1 14 4.5 0.0 3.2 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein SET PF00856.28 KIY73930.1 - 1.7e-16 61.1 1.8 3.5e-16 60.1 0.1 2.4 2 1 0 2 2 2 1 SET domain preSET_CXC PF18264.1 KIY73930.1 - 2.3e-08 34.3 17.2 2.3e-08 34.3 17.2 4.1 4 1 0 4 4 4 1 CXC domain DUF726 PF05277.12 KIY73931.1 - 3.5e-120 401.0 0.7 5.4e-120 400.4 0.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF726) UPF0565 PF10561.9 KIY73931.1 - 0.16 11.1 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 ATG16 PF08614.11 KIY73932.1 - 0.0069 16.6 11.1 0.0069 16.6 11.1 2.0 2 1 0 2 2 2 1 Autophagy protein 16 (ATG16) DUF4407 PF14362.6 KIY73932.1 - 0.26 10.6 1.1 0.36 10.1 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DivIC PF04977.15 KIY73932.1 - 1.5 8.6 4.8 4.3 7.2 2.7 2.2 2 0 0 2 2 2 0 Septum formation initiator FUSC PF04632.12 KIY73932.1 - 4.3 5.8 4.7 7 5.0 4.7 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family FlgN PF05130.12 KIY73934.1 - 0.004 17.7 0.4 0.004 17.7 0.4 3.1 3 0 0 3 3 3 1 FlgN protein RNase_H PF00075.24 KIY73935.1 - 7.6e-06 26.2 0.1 1.3e-05 25.5 0.1 1.3 1 0 0 1 1 1 1 RNase H RVT_1 PF00078.27 KIY73936.1 - 3.9e-08 33.1 0.0 4.4e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FAA_hydro_N_2 PF18288.1 KIY73936.1 - 0.14 12.6 0.6 6 7.4 0.0 2.2 2 0 0 2 2 2 0 Fumarylacetoacetase N-terminal domain 2 Exo_endo_phos PF03372.23 KIY73937.1 - 0.00035 20.2 0.0 0.00046 19.8 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family CO_dh PF02552.16 KIY73937.1 - 0.048 13.4 0.2 0.1 12.4 0.2 1.6 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit SAM_Exu PF18609.1 KIY73938.1 - 0.23 11.6 2.1 0.45 10.6 0.3 2.5 3 0 0 3 3 3 0 Exuperantia SAM-like domain Plk4_PB2 PF18409.1 KIY73938.1 - 0.34 11.6 3.3 3.2 8.5 0.3 3.1 3 0 0 3 3 3 0 Polo-like Kinase 4 Polo Box 2 DUF1664 PF07889.12 KIY73938.1 - 1.2 9.1 7.7 1.2 9.2 0.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF3450 PF11932.8 KIY73938.1 - 2.3 7.5 25.0 0.2 10.9 12.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Prominin PF05478.11 KIY73938.1 - 7.6 4.3 7.6 5.3 4.9 0.3 2.1 2 0 0 2 2 2 0 Prominin SARAF PF06682.12 KIY73941.1 - 1.3e-44 153.2 0.4 3.6e-44 151.8 0.4 1.6 1 1 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis TUG-UBL1 PF11470.8 KIY73942.1 - 0.083 13.1 0.1 0.15 12.3 0.1 1.4 1 0 0 1 1 1 0 TUG ubiquitin-like domain Pyr_redox_2 PF07992.14 KIY73943.1 - 1.2e-27 97.0 0.0 3.8e-22 78.9 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KIY73943.1 - 5.8e-10 39.6 0.2 1.8e-06 28.4 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KIY73943.1 - 0.00011 21.2 0.3 1.7 7.4 0.1 3.1 3 0 0 3 3 3 2 Tryptophan halogenase Pyr_redox_3 PF13738.6 KIY73943.1 - 0.00045 19.6 0.0 0.0014 17.9 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KIY73943.1 - 0.00068 19.3 0.0 1.5 8.3 0.3 2.9 3 0 0 3 3 3 2 FAD dependent oxidoreductase K_oxygenase PF13434.6 KIY73943.1 - 0.00092 18.5 0.0 0.2 10.8 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NCU-G1 PF15065.6 KIY73943.1 - 0.041 12.9 0.0 0.081 11.9 0.0 1.4 1 1 0 1 1 1 0 Lysosomal transcription factor, NCU-G1 TrkA_N PF02254.18 KIY73943.1 - 0.2 12.0 0.1 31 4.9 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain ApbA_C PF08546.11 KIY73946.1 - 7e-16 58.6 0.0 3.7e-14 53.0 0.0 2.4 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 KIY73946.1 - 5.6e-14 52.0 0.0 8.6e-14 51.4 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.27 KIY73946.1 - 0.0065 17.0 0.7 0.028 15.0 0.3 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KIY73946.1 - 0.037 14.5 0.1 0.08 13.4 0.1 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding DAO PF01266.24 KIY73946.1 - 0.061 12.9 1.3 0.13 11.8 1.1 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase Arrestin_N PF00339.29 KIY73947.1 - 0.00019 21.5 0.1 0.0011 19.0 0.1 2.1 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain zf-HC2 PF13490.6 KIY73947.1 - 0.14 12.5 0.3 0.49 10.7 0.3 1.9 1 0 0 1 1 1 0 Putative zinc-finger Nucleoporin_FG PF13634.6 KIY73948.1 - 9.8e-12 45.6 147.8 0.0014 19.5 11.6 8.5 3 3 5 8 8 8 8 Nucleoporin FG repeat region CPSase_L_D2 PF02786.17 KIY73951.1 - 1.5e-114 380.7 0.3 8.8e-85 283.5 0.1 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 KIY73951.1 - 4.6e-48 162.3 0.0 1.9e-47 160.3 0.0 2.1 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 KIY73951.1 - 2.2e-46 158.1 0.0 1.7e-45 155.2 0.0 2.3 2 0 0 2 2 2 1 Glutamine amidotransferase class-I OTCace_N PF02729.21 KIY73951.1 - 7e-46 155.9 0.0 2.2e-45 154.3 0.0 1.9 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.19 KIY73951.1 - 1.5e-38 131.9 0.2 3.5e-38 130.7 0.2 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 KIY73951.1 - 7.7e-32 110.5 0.0 1.9e-31 109.3 0.0 1.7 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Dala_Dala_lig_C PF07478.13 KIY73951.1 - 7.7e-20 71.3 0.4 1.8e-09 37.4 0.0 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus MGS PF02142.22 KIY73951.1 - 1.3e-18 67.0 0.0 5.5e-18 65.0 0.0 2.2 2 0 0 2 2 2 1 MGS-like domain ATP-grasp PF02222.22 KIY73951.1 - 2e-18 66.6 0.2 7e-09 35.5 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 KIY73951.1 - 1.2e-09 38.0 0.1 0.00056 19.7 0.0 2.7 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Peptidase_C26 PF07722.13 KIY73951.1 - 3e-06 27.1 0.0 0.00034 20.5 0.0 2.6 1 1 0 1 1 1 1 Peptidase C26 ATP-grasp_3 PF02655.14 KIY73951.1 - 7.2e-06 26.1 0.2 0.071 13.2 0.0 2.9 3 0 0 3 3 3 2 ATP-grasp domain DJ-1_PfpI PF01965.24 KIY73951.1 - 0.002 18.0 0.0 0.82 9.5 0.0 3.9 4 0 0 4 4 4 1 DJ-1/PfpI family RimK PF08443.11 KIY73951.1 - 0.018 14.7 0.0 1.9 8.0 0.0 2.6 2 0 0 2 2 2 0 RimK-like ATP-grasp domain GARS_A PF01071.19 KIY73951.1 - 0.092 12.5 0.1 1.6 8.5 0.0 2.5 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Syntaxin PF00804.25 KIY73952.1 - 4.4e-25 88.5 14.2 4.4e-25 88.5 14.2 2.1 2 1 0 2 2 2 1 Syntaxin Syntaxin_2 PF14523.6 KIY73952.1 - 5.4e-07 29.9 16.0 1.6e-06 28.4 9.3 3.0 2 1 1 3 3 3 1 Syntaxin-like protein SNARE PF05739.19 KIY73952.1 - 1.9e-05 24.5 0.2 1.9e-05 24.5 0.2 2.7 3 0 0 3 3 3 1 SNARE domain MCPsignal PF00015.21 KIY73952.1 - 0.0016 18.3 11.5 0.0027 17.5 3.6 2.2 2 0 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Transcrip_act PF04949.13 KIY73952.1 - 0.0016 18.3 3.5 0.67 9.8 0.3 2.3 2 0 0 2 2 2 2 Transcriptional activator DUF615 PF04751.14 KIY73952.1 - 0.0025 17.8 10.9 0.0038 17.2 10.2 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF615) ABC_tran_CTD PF16326.5 KIY73952.1 - 0.025 14.8 10.0 0.027 14.7 3.3 3.3 2 2 2 4 4 4 0 ABC transporter C-terminal domain ETRAMP PF09716.10 KIY73952.1 - 0.026 14.6 0.3 0.046 13.8 0.3 1.6 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Serine_rich PF08824.10 KIY73952.1 - 0.058 13.4 3.9 0.66 10.0 0.7 2.3 2 0 0 2 2 2 0 Serine rich protein interaction domain SKA1 PF07160.12 KIY73952.1 - 0.067 13.0 0.4 0.067 13.0 0.4 2.6 2 1 0 2 2 2 0 Spindle and kinetochore-associated protein 1 DUF4256 PF14066.6 KIY73952.1 - 0.08 12.6 1.7 0.13 11.9 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4256) SMBP PF16785.5 KIY73952.1 - 0.14 12.3 4.1 0.28 11.4 2.0 2.2 1 1 1 2 2 2 0 Small metal-binding protein FUSC PF04632.12 KIY73952.1 - 0.16 10.5 15.9 0.71 8.3 16.0 1.8 1 1 0 1 1 1 0 Fusaric acid resistance protein family DotU PF09850.9 KIY73952.1 - 1.1 9.0 5.0 1 9.0 0.4 2.9 1 1 2 3 3 3 0 Type VI secretion system protein DotU SNN_transmemb PF09049.10 KIY73952.1 - 1.3 9.0 3.6 2.4 8.2 3.6 1.4 1 0 0 1 1 1 0 Stannin transmembrane PAS_10 PF13596.6 KIY73952.1 - 1.5 9.4 4.6 3.9 8.1 0.3 2.6 1 1 1 2 2 2 0 PAS domain Fib_alpha PF08702.10 KIY73952.1 - 3.4 7.8 11.9 8.3 6.6 0.3 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF3349 PF11829.8 KIY73952.1 - 6.4 7.6 8.0 2.2 9.1 0.4 3.2 2 2 1 3 3 3 0 Protein of unknown function (DUF3349) Ofd1_CTDD PF10637.9 KIY73953.1 - 7.7e-77 258.1 0.0 1.3e-74 250.8 0.0 2.2 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 KIY73953.1 - 3.7e-29 101.2 0.0 8.3e-29 100.1 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 KIY73953.1 - 1.1e-13 51.8 0.0 2.5e-13 50.7 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Zn_clus PF00172.18 KIY73954.1 - 9e-05 22.5 8.2 9e-05 22.5 8.2 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3546 PF12066.8 KIY73954.1 - 0.046 13.9 0.0 0.098 12.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3546) Gly_transf_sug PF04488.15 KIY73955.1 - 5e-07 30.3 0.1 9.1e-07 29.4 0.1 1.5 1 1 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 KIY73955.1 - 7.2e-05 22.3 0.2 0.00011 21.7 0.2 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein RRM_1 PF00076.22 KIY73956.1 - 1.3e-22 79.4 0.1 6.8e-11 41.8 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRP14 PF15459.6 KIY73956.1 - 0.019 15.5 3.4 0.019 15.5 3.4 2.2 2 0 0 2 2 2 0 60S ribosome biogenesis protein Rrp14 Nup35_RRM_2 PF14605.6 KIY73956.1 - 0.021 14.8 0.0 0.048 13.7 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Sugar_tr PF00083.24 KIY73957.1 - 3.2e-108 362.5 20.1 3.7e-108 362.3 20.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY73957.1 - 1.2e-34 119.8 28.8 4.7e-30 104.7 11.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Alpha-L-AF_C PF06964.12 KIY73958.1 - 8.9e-29 100.8 0.0 1.5e-28 100.0 0.0 1.4 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain Glyco_hydro_79n PF03662.14 KIY73958.1 - 0.012 14.6 0.2 0.047 12.6 0.1 1.8 2 0 0 2 2 2 0 Glycosyl hydrolase family 79, N-terminal domain Glyco_hydro_44 PF12891.7 KIY73958.1 - 0.015 15.3 0.4 0.04 13.9 0.3 1.7 1 1 0 1 1 1 0 Glycoside hydrolase family 44 Cyt-b5 PF00173.28 KIY73960.1 - 1.7e-20 72.9 0.3 2.3e-20 72.5 0.3 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Ribonucleas_3_3 PF14622.6 KIY73961.1 - 4.4e-16 59.2 0.0 6.2e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 KIY73961.1 - 3.4e-14 53.3 0.0 1.5e-13 51.3 0.0 1.9 1 1 0 1 1 1 1 Ribonuclease III domain dsrm PF00035.26 KIY73961.1 - 3.2e-06 27.7 0.0 6.7e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif PAPS_reduct PF01507.19 KIY73962.1 - 1.7e-36 125.8 0.0 2.5e-36 125.3 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family RNA_pol_Rpb2_6 PF00562.28 KIY73963.1 - 2.7e-109 365.8 0.0 5e-109 364.9 0.0 1.4 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KIY73963.1 - 1.2e-33 116.4 0.0 2e-33 115.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 KIY73963.1 - 1.6e-28 98.7 0.0 3.8e-28 97.5 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.12 KIY73963.1 - 5.7e-21 74.3 0.0 1.2e-20 73.2 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.20 KIY73963.1 - 1.9e-18 66.6 0.1 6e-15 55.4 0.1 2.5 2 0 0 2 2 2 2 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 KIY73963.1 - 1.9e-17 63.5 0.0 3.6e-17 62.6 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 Prim_Zn_Ribbon PF08273.12 KIY73963.1 - 0.28 11.5 4.9 11 6.3 0.1 3.0 3 0 0 3 3 3 0 Zinc-binding domain of primase-helicase Nucleoporin2 PF04096.14 KIY73964.1 - 1.2e-40 139.0 0.0 1.9e-40 138.4 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 KIY73964.1 - 7.4e-07 29.9 277.4 4.5e-05 24.2 41.1 10.2 2 2 5 9 9 9 4 Nucleoporin FG repeat region Abhydrolase_2 PF02230.16 KIY73965.1 - 2.5e-53 181.1 0.0 3.5e-53 180.6 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 KIY73965.1 - 5.2e-07 29.2 1.6 0.11 11.8 0.0 3.1 2 1 1 3 3 3 3 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KIY73965.1 - 1.4e-06 29.1 0.0 1.8e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.13 KIY73965.1 - 0.00072 19.3 0.0 0.0016 18.1 0.0 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.20 KIY73965.1 - 0.001 18.8 1.4 0.014 15.0 0.8 2.6 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 KIY73965.1 - 0.0019 18.0 0.0 0.003 17.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 KIY73965.1 - 0.0019 17.8 0.0 0.0039 16.8 0.0 1.5 1 0 0 1 1 1 1 Dienelactone hydrolase family Esterase_phd PF10503.9 KIY73965.1 - 0.0064 16.0 0.1 0.73 9.3 0.0 2.2 2 0 0 2 2 2 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 KIY73965.1 - 0.018 14.5 0.3 4.8 6.6 0.2 2.5 1 1 1 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 KIY73965.1 - 0.018 14.9 0.0 0.033 14.1 0.0 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold LIP PF03583.14 KIY73965.1 - 0.028 13.7 0.1 0.58 9.4 0.0 2.2 2 0 0 2 2 2 0 Secretory lipase Esterase PF00756.20 KIY73965.1 - 0.17 11.5 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Abhydrolase_2 PF02230.16 KIY73966.1 - 4.3e-40 137.8 0.0 5.7e-40 137.4 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Cutinase PF01083.22 KIY73966.1 - 0.11 12.4 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Cutinase Sugar_tr PF00083.24 KIY73967.1 - 9.8e-121 403.8 16.6 1.1e-120 403.6 16.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY73967.1 - 1.7e-23 83.1 29.5 2.3e-23 82.7 24.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Asp PF00026.23 KIY73968.1 - 3e-37 128.7 0.0 5.2e-37 127.9 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIY73968.1 - 7e-06 26.4 5.7 0.0011 19.3 3.8 3.2 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal PhoLip_ATPase_C PF16212.5 KIY73969.1 - 7e-74 248.7 26.5 1.5e-73 247.6 26.5 1.6 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KIY73969.1 - 2.5e-22 78.3 0.5 5.7e-22 77.2 0.5 1.7 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KIY73969.1 - 1.8e-12 48.0 2.8 2.6e-07 31.2 0.5 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KIY73969.1 - 1.7e-10 40.9 0.0 6.4e-10 39.0 0.0 1.9 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KIY73969.1 - 0.00013 21.8 1.4 0.0051 16.6 0.3 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KIY73969.1 - 0.065 13.6 0.0 1.9 8.8 0.0 2.4 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KIY73969.1 - 0.074 12.6 2.5 0.078 12.5 0.0 2.3 2 1 1 3 3 3 0 E1-E2 ATPase Peptidase_M28 PF04389.17 KIY73970.1 - 1.3e-25 90.2 0.0 2.5e-25 89.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KIY73970.1 - 0.00019 21.2 0.0 0.00033 20.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 HIG_1_N PF04588.13 KIY73971.1 - 6.9e-06 26.2 0.8 1.4e-05 25.2 0.8 1.5 1 0 0 1 1 1 1 Hypoxia induced protein conserved region Bacteriocin_IIc PF10439.9 KIY73971.1 - 0.1 12.8 3.2 0.28 11.3 0.2 2.6 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Methyltransf_11 PF08241.12 KIY73972.1 - 7.2e-11 42.6 0.0 1.8e-10 41.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIY73972.1 - 7.2e-11 42.2 0.0 1.1e-10 41.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KIY73972.1 - 5.6e-09 36.6 0.0 1.3e-08 35.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIY73972.1 - 6.9e-07 29.9 0.0 1.7e-06 28.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KIY73972.1 - 4.4e-05 23.3 0.0 8.7e-05 22.4 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain RrnaAD PF00398.20 KIY73972.1 - 0.0072 15.4 0.0 0.0094 15.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MTS PF05175.14 KIY73972.1 - 0.0095 15.5 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 KIY73972.1 - 0.023 14.7 0.0 0.036 14.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DREV PF05219.12 KIY73972.1 - 0.092 11.8 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase MetW PF07021.12 KIY73972.1 - 0.14 11.7 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW HRI1 PF16815.5 KIY73975.1 - 2e-36 125.8 0.7 2.9e-36 125.3 0.7 1.3 1 1 0 1 1 1 1 Protein HRI1 Phosphoesterase PF04185.14 KIY73976.1 - 2.1e-28 99.6 6.9 3.1e-27 95.7 7.0 2.0 1 1 0 1 1 1 1 Phosphoesterase family Sulfatase PF00884.23 KIY73976.1 - 0.00065 19.2 0.2 0.0013 18.2 0.2 1.5 1 1 0 1 1 1 1 Sulfatase zf-RING_11 PF17123.5 KIY73977.1 - 6.9e-14 51.3 3.3 1.5e-13 50.3 3.3 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 KIY73977.1 - 6.7e-10 39.1 3.1 6.7e-10 39.1 3.1 1.6 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4 PF00097.25 KIY73977.1 - 1.9e-07 30.8 3.4 4.1e-07 29.8 3.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KIY73977.1 - 9.6e-07 28.5 4.8 2.1e-06 27.5 4.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIY73977.1 - 3.1e-06 27.0 3.4 5.2e-06 26.3 3.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KIY73977.1 - 3.2e-05 23.9 3.2 6.5e-05 22.9 3.2 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KIY73977.1 - 0.00084 19.1 1.9 0.0016 18.3 1.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KIY73977.1 - 0.00085 19.3 0.8 0.0015 18.5 0.8 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KIY73977.1 - 0.0024 18.1 5.7 0.0089 16.3 5.7 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain PHD PF00628.29 KIY73977.1 - 0.005 16.7 3.5 0.0052 16.6 2.1 1.8 2 0 0 2 2 2 1 PHD-finger Zn_ribbon_17 PF17120.5 KIY73977.1 - 0.02 14.5 0.9 0.039 13.6 0.9 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING-like PF08746.11 KIY73977.1 - 0.033 14.5 2.0 0.1 12.9 1.2 2.0 2 0 0 2 2 2 0 RING-like domain Ima1_N PF09779.9 KIY73977.1 - 0.051 14.4 0.2 0.082 13.8 0.2 1.3 1 0 0 1 1 1 0 Ima1 N-terminal domain Prok-RING_4 PF14447.6 KIY73977.1 - 0.11 12.3 3.0 0.24 11.3 3.0 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 KIY73977.1 - 0.18 11.6 4.2 0.41 10.5 4.2 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Glyco_hydro_18 PF00704.28 KIY73978.1 - 9.2e-67 226.0 0.2 1.2e-66 225.6 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Sugar_tr PF00083.24 KIY73979.1 - 5.7e-91 305.6 18.2 6.8e-91 305.4 18.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY73979.1 - 1.4e-30 106.4 55.4 1e-28 100.3 31.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KIY73979.1 - 7.2e-07 28.0 3.4 7.2e-07 28.0 3.4 2.4 2 1 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 KIY73979.1 - 1.3e-06 27.2 15.2 0.0022 16.6 2.4 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein BT1 PF03092.16 KIY73979.1 - 7 4.7 8.8 1.6 6.9 2.2 2.4 2 1 0 2 2 2 0 BT1 family UreF PF01730.16 KIY73980.1 - 1.3e-26 93.7 0.4 2e-26 93.2 0.4 1.1 1 0 0 1 1 1 1 UreF RNF220 PF15926.5 KIY73981.1 - 7.6e-15 55.2 10.7 7.6e-15 55.2 10.7 2.4 2 1 0 2 2 2 1 E3 ubiquitin-protein ligase RNF220 zf-C3HC4_2 PF13923.6 KIY73981.1 - 3.4e-09 36.4 24.9 4.3e-09 36.1 14.6 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KIY73981.1 - 4.7e-06 26.4 19.7 7.8e-05 22.5 11.7 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIY73981.1 - 3.3e-05 23.8 20.3 4.8e-05 23.2 12.4 3.2 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KIY73981.1 - 0.00015 21.6 13.9 0.00015 21.6 13.9 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIY73981.1 - 0.00025 21.3 26.9 0.00053 20.3 16.2 3.2 3 0 0 3 3 3 1 Ring finger domain zf-WRNIP1_ubi PF18279.1 KIY73981.1 - 0.00074 20.0 0.7 5.9 7.8 0.2 3.6 3 0 0 3 3 3 1 Werner helicase-interacting protein 1 ubiquitin-binding domain zf-RING_UBOX PF13445.6 KIY73981.1 - 0.00091 19.2 8.0 0.00091 19.2 8.0 4.3 4 0 0 4 4 4 1 RING-type zinc-finger Siva PF05458.12 KIY73981.1 - 0.016 14.9 2.7 0.037 13.7 2.7 1.6 1 0 0 1 1 1 0 Cd27 binding protein (Siva) ECM11 PF15463.6 KIY73981.1 - 0.028 15.0 0.3 0.078 13.6 0.3 1.8 1 0 0 1 1 1 0 Extracellular mutant protein 11 Prok-RING_4 PF14447.6 KIY73981.1 - 0.044 13.7 20.1 3 7.8 14.0 4.1 3 1 1 4 4 4 0 Prokaryotic RING finger family 4 KfrA_N PF11740.8 KIY73981.1 - 0.32 11.7 0.0 0.32 11.7 0.0 2.9 3 0 0 3 3 3 0 Plasmid replication region DNA-binding N-term zf-RING_6 PF14835.6 KIY73981.1 - 1.2 9.1 16.2 0.034 14.0 8.8 2.2 3 0 0 3 3 2 0 zf-RING of BARD1-type protein PRP21_like_P PF12230.8 KIY73981.1 - 1.5 8.6 5.9 1.1 9.1 0.0 3.0 3 1 0 3 3 3 0 Pre-mRNA splicing factor PRP21 like protein zf-Nse PF11789.8 KIY73981.1 - 1.7 8.6 14.9 0.22 11.4 6.0 3.0 3 0 0 3 3 3 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 KIY73981.1 - 9.1 6.5 21.3 3.7 7.8 12.0 3.5 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING AFG1_ATPase PF03969.16 KIY73982.1 - 1.6e-94 316.8 0.0 2.6e-91 306.2 0.0 2.0 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.6 KIY73982.1 - 0.00012 22.5 0.1 0.058 13.8 0.0 2.7 1 1 0 2 2 2 2 AAA ATPase domain TniB PF05621.11 KIY73982.1 - 0.0024 17.3 0.0 0.0061 16.0 0.0 1.6 1 0 0 1 1 1 1 Bacterial TniB protein AAA_22 PF13401.6 KIY73982.1 - 0.012 15.9 0.0 0.036 14.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 KIY73982.1 - 0.026 15.0 0.0 0.066 13.6 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Bac_DnaA PF00308.18 KIY73982.1 - 0.039 13.8 0.1 0.28 11.0 0.1 2.1 1 1 0 1 1 1 0 Bacterial dnaA protein Peptidase_S28 PF05577.12 KIY73983.1 - 1.4e-47 162.5 0.2 2.8e-47 161.5 0.2 1.4 1 1 0 1 1 1 1 Serine carboxypeptidase S28 DUF4091 PF13320.6 KIY73983.1 - 0.039 14.1 0.0 0.17 12.0 0.0 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4091) Peptidase_S28 PF05577.12 KIY73984.1 - 6.4e-49 166.9 0.1 9.3e-48 163.1 0.1 2.0 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S9 PF00326.21 KIY73984.1 - 0.0039 16.7 0.3 0.011 15.2 0.2 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family Sod_Fe_C PF02777.18 KIY73984.1 - 0.038 14.1 0.0 0.098 12.8 0.0 1.7 1 0 0 1 1 1 0 Iron/manganese superoxide dismutases, C-terminal domain Peptidase_S37 PF05576.11 KIY73984.1 - 0.06 12.0 0.0 0.11 11.1 0.0 1.4 1 0 0 1 1 1 0 PS-10 peptidase S37 RIX1 PF08167.12 KIY73985.1 - 0.13 12.0 0.0 0.13 12.0 0.0 1.0 1 0 0 1 1 1 0 rRNA processing/ribosome biogenesis MCM PF00493.23 KIY73986.1 - 1.4e-104 348.0 0.6 2.4e-104 347.3 0.6 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KIY73986.1 - 8.1e-37 125.9 0.1 1.6e-36 124.9 0.1 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KIY73986.1 - 1.1e-25 89.9 0.4 3.2e-25 88.4 0.4 1.9 1 0 0 1 1 1 1 MCM AAA-lid domain MCM6_C PF18263.1 KIY73986.1 - 3.2e-23 82.0 0.1 8.2e-23 80.7 0.1 1.7 1 0 0 1 1 1 1 MCM6 C-terminal winged-helix domain MCM_N PF14551.6 KIY73986.1 - 4.8e-20 72.1 0.0 1.7e-19 70.3 0.0 2.0 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KIY73986.1 - 5.1e-08 32.5 0.0 2.7e-07 30.2 0.0 2.0 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KIY73986.1 - 0.00023 21.1 0.0 0.0008 19.3 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KIY73986.1 - 0.0011 18.7 0.0 0.0023 17.7 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 KIY73986.1 - 0.0024 17.9 0.0 0.021 14.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) S100PBPR PF15427.6 KIY73986.1 - 0.027 13.8 0.9 0.053 12.8 0.9 1.4 1 0 0 1 1 1 0 S100P-binding protein PROL5-SMR PF15621.6 KIY73988.1 - 0.0025 18.3 0.2 0.0043 17.5 0.2 1.3 1 0 0 1 1 1 1 Proline-rich submaxillary gland androgen-regulated family SET PF00856.28 KIY73989.1 - 1.6e-13 51.4 1.9 2.9e-13 50.6 0.0 2.4 2 1 0 2 2 2 1 SET domain Pre-SET PF05033.16 KIY73989.1 - 1.9e-11 44.5 6.8 1.9e-11 44.5 6.8 2.1 2 0 0 2 2 2 1 Pre-SET motif Complex1_LYR PF05347.15 KIY73990.1 - 3.1e-08 33.5 0.5 5.2e-08 32.8 0.5 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) RRN3 PF05327.11 KIY73991.1 - 4e-160 534.1 1.7 1.3e-159 532.3 0.0 2.1 1 1 1 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 BSP_II PF05432.11 KIY73991.1 - 5.5 6.6 9.2 0.2 11.3 1.5 1.9 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) LNS2 PF08235.13 KIY73992.1 - 5.3e-99 330.3 0.0 7.1e-99 329.9 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 KIY73992.1 - 4.6e-35 119.7 0.0 1.7e-34 117.8 0.0 1.9 2 0 0 2 2 2 1 lipin, N-terminal conserved region Lipin_mid PF16876.5 KIY73992.1 - 0.15 12.2 0.0 0.36 11.0 0.0 1.7 1 0 0 1 1 1 0 Lipin/Ned1/Smp2 multi-domain protein middle domain F-box-like PF12937.7 KIY73993.1 - 0.042 13.7 1.9 0.058 13.3 0.2 2.2 2 0 0 2 2 2 0 F-box-like adh_short PF00106.25 KIY73994.1 - 3e-35 121.5 0.0 4.7e-35 120.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIY73994.1 - 2.5e-26 92.7 0.0 3.4e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIY73994.1 - 1.4e-09 38.1 0.0 1.9e-09 37.7 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KIY73994.1 - 0.0021 17.6 0.1 0.003 17.0 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KIY73994.1 - 0.067 12.3 0.1 0.11 11.6 0.1 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain DUF1776 PF08643.10 KIY73994.1 - 0.11 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) SAP18 PF06487.12 KIY73995.1 - 8.3e-32 110.3 0.0 1.1e-31 109.9 0.0 1.2 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Cu_amine_oxid PF01179.20 KIY73996.1 - 1.1e-128 429.6 0.3 1.6e-128 429.2 0.3 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.10 KIY73996.1 - 7.6e-10 38.4 0.1 2.1e-09 37.0 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) RTA1 PF04479.13 KIY73997.1 - 4.1e-52 176.8 6.2 5.2e-52 176.5 6.2 1.1 1 0 0 1 1 1 1 RTA1 like protein Oxidored_FMN PF00724.20 KIY73998.1 - 5.6e-88 295.5 0.0 6.4e-88 295.3 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Oxidored_FMN PF00724.20 KIY73999.1 - 6.5e-92 308.4 0.0 7.8e-92 308.2 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family EF-hand_1 PF00036.32 KIY74001.1 - 1.1e-19 68.4 0.1 1.4e-05 24.3 0.0 4.4 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 KIY74001.1 - 6.2e-18 63.1 0.1 2e-05 24.2 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 KIY74001.1 - 1.3e-16 60.8 0.0 2.6e-07 31.0 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KIY74001.1 - 2.1e-14 52.3 0.2 0.0047 16.4 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 KIY74001.1 - 1.4e-11 44.1 1.0 0.00016 21.5 0.1 4.2 3 1 1 4 4 4 2 EF-hand domain pair DUF5640 PF18692.1 KIY74001.1 - 0.13 12.3 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5640) DUF4203 PF13886.6 KIY74002.1 - 1.3e-13 51.1 20.6 2.3e-13 50.3 20.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) EI24 PF07264.11 KIY74004.1 - 1.2e-07 32.2 10.2 1.9e-07 31.5 10.2 1.4 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) DUF1129 PF06570.11 KIY74004.1 - 0.74 9.3 4.3 0.66 9.4 0.5 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1129) BTB PF00651.31 KIY74005.1 - 0.00027 21.1 0.0 0.00054 20.2 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain SBDS PF01172.18 KIY74006.1 - 1e-18 67.2 0.2 1.2e-18 66.9 0.2 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Annexin PF00191.20 KIY74007.1 - 4.3e-50 167.6 0.1 1.3e-14 54.0 0.1 4.2 4 0 0 4 4 4 4 Annexin S-AdoMet_synt_C PF02773.16 KIY74008.1 - 0.031 14.3 0.0 0.06 13.3 0.0 1.5 1 1 0 1 1 1 0 S-adenosylmethionine synthetase, C-terminal domain FTR1 PF03239.14 KIY74008.1 - 0.84 8.7 8.7 1.1 8.4 2.6 2.1 1 1 1 2 2 2 0 Iron permease FTR1 family Glyco_hydro_71 PF03659.14 KIY74009.1 - 1.5e-97 326.8 14.5 2.1e-97 326.3 14.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 WSC PF01822.19 KIY74009.1 - 3.2e-49 165.0 61.0 1.6e-18 66.7 14.5 3.5 3 0 0 3 3 3 3 WSC domain APH PF01636.23 KIY74011.1 - 2.2e-14 54.0 0.0 3.6e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 KIY74011.1 - 8.5e-10 38.0 0.0 0.00011 21.3 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) Pkinase PF00069.25 KIY74011.1 - 0.0049 16.3 0.0 1.3 8.3 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Choline_kinase PF01633.20 KIY74011.1 - 0.01 15.5 0.0 0.091 12.3 0.0 2.1 2 0 0 2 2 2 0 Choline/ethanolamine kinase EcKinase PF02958.20 KIY74011.1 - 0.044 13.1 0.0 0.074 12.4 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase RIO1 PF01163.22 KIY74011.1 - 0.15 11.7 0.0 1.1 8.9 0.0 2.2 2 0 0 2 2 2 0 RIO1 family Meth_synt_2 PF01717.18 KIY74013.1 - 1.5e-147 491.1 0.0 3.4e-145 483.3 0.0 2.2 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 KIY74013.1 - 5.4e-114 380.9 0.0 1.3e-107 359.9 0.0 2.4 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain SHOCT PF09851.9 KIY74013.1 - 3.9 7.3 7.3 0.33 10.7 1.3 2.4 2 0 0 2 2 2 0 Short C-terminal domain ADH_N PF08240.12 KIY74014.1 - 1.5e-29 102.0 1.1 3.1e-29 101.0 1.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KIY74014.1 - 1.4e-21 76.8 0.0 2.1e-21 76.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KIY74014.1 - 3.1e-07 31.5 0.1 5.6e-07 30.7 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_25 PF13649.6 KIY74014.1 - 0.00021 21.9 0.0 0.00042 20.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Glu_dehyd_C PF16912.5 KIY74014.1 - 0.00046 19.7 0.4 0.54 9.7 0.1 2.3 2 0 0 2 2 2 2 Glucose dehydrogenase C-terminus Methyltransf_12 PF08242.12 KIY74014.1 - 0.025 15.3 0.0 0.05 14.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 KIY74014.1 - 0.055 14.1 0.0 0.11 13.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 KIY74014.1 - 0.078 12.8 0.0 0.16 11.8 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 KIY74014.1 - 0.15 11.4 0.1 0.28 10.5 0.0 1.4 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Ribosomal_S19 PF00203.21 KIY74015.1 - 7e-27 93.1 0.0 1e-26 92.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 ICMT PF04140.14 KIY74016.1 - 8.4e-25 87.0 0.8 1.6e-24 86.1 0.8 1.4 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KIY74016.1 - 6.7e-14 52.2 2.1 6.7e-14 52.2 2.1 2.1 2 0 0 2 2 2 1 Phospholipid methyltransferase NnrU PF07298.11 KIY74016.1 - 0.00025 20.6 0.5 0.00025 20.6 0.5 1.7 2 0 0 2 2 2 1 NnrU protein GTP_EFTU PF00009.27 KIY74017.1 - 1.8e-52 177.8 0.0 2.8e-52 177.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 KIY74017.1 - 2.2e-15 56.5 0.0 5.2e-15 55.3 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 KIY74017.1 - 2.6e-14 53.0 0.0 7.7e-07 29.1 0.0 2.5 2 0 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KIY74017.1 - 6.3e-06 26.5 0.0 1.5e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KIY74017.1 - 0.00027 21.0 0.0 0.00053 20.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RF3_C PF16658.5 KIY74017.1 - 0.046 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain SRPRB PF09439.10 KIY74017.1 - 0.18 11.2 0.0 0.58 9.6 0.0 1.7 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit TT_ORF2 PF02957.15 KIY74018.1 - 0.15 13.0 3.0 0.25 12.3 3.0 1.4 1 0 0 1 1 1 0 TT viral ORF2 SWIRM-assoc_2 PF16496.5 KIY74018.1 - 0.6 8.9 8.7 0.13 11.1 5.9 1.4 2 0 0 2 2 2 0 SWIRM-associated domain at the N-terminal PBP1_TM PF14812.6 KIY74018.1 - 2.3 8.7 8.5 3.3 8.1 8.5 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PIG-S PF10510.9 KIY74019.1 - 5.4e-106 355.4 5.9 9.4e-97 325.0 0.9 2.0 1 1 1 2 2 2 2 Phosphatidylinositol-glycan biosynthesis class S protein PARP_reg PF02877.14 KIY74019.1 - 0.075 13.1 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Poly(ADP-ribose) polymerase, regulatory domain Myb_DNA-binding PF00249.31 KIY74021.1 - 8.7e-09 35.4 0.0 0.00024 21.2 0.0 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KIY74021.1 - 0.00013 21.8 2.0 0.37 10.7 0.2 2.6 2 0 0 2 2 2 2 Myb DNA-binding like DUF4085 PF13315.6 KIY74021.1 - 0.012 15.2 0.1 1.8 8.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4085) Myb_DNA-bind_6 PF13921.6 KIY74021.1 - 0.015 15.5 2.4 0.075 13.3 0.1 2.8 3 0 0 3 3 3 0 Myb-like DNA-binding domain DUF874 PF05917.11 KIY74022.1 - 0.047 12.7 2.7 0.068 12.2 2.7 1.2 1 0 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) Fez1 PF06818.15 KIY74022.1 - 0.16 12.4 18.4 0.027 14.9 12.8 2.0 1 1 1 2 2 2 0 Fez1 U79_P34 PF03064.16 KIY74022.1 - 5 6.4 12.1 9.5 5.5 12.1 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 RNase_T PF00929.24 KIY74025.1 - 0.0001 22.9 0.0 0.00021 21.9 0.0 1.6 1 0 0 1 1 1 1 Exonuclease CHORD PF04968.12 KIY74025.1 - 0.0014 19.3 4.6 0.0034 18.1 4.6 1.6 1 0 0 1 1 1 1 CHORD DnaJ PF00226.31 KIY74026.1 - 3.9e-19 68.5 0.1 6e-19 67.9 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain FNIP PF05725.12 KIY74027.1 - 0.079 13.1 0.1 1.3 9.2 0.0 2.6 1 1 1 2 2 2 0 FNIP Repeat TRAM_LAG1_CLN8 PF03798.16 KIY74028.1 - 1.8e-33 116.0 18.7 1.8e-33 116.0 18.7 1.7 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 KIY74028.1 - 5.5e-12 45.2 1.8 1.5e-11 43.7 1.8 1.8 1 0 0 1 1 1 1 TRAM1-like protein FMN_bind_2 PF04299.12 KIY74029.1 - 4.2e-48 163.3 0.1 6e-48 162.7 0.1 1.2 1 0 0 1 1 1 1 Putative FMN-binding domain TRAM_LAG1_CLN8 PF03798.16 KIY74030.1 - 3.1e-29 102.1 23.6 3.1e-29 102.1 23.6 1.6 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 KIY74030.1 - 9e-17 60.5 0.4 2.5e-16 59.1 0.4 1.8 1 0 0 1 1 1 1 TRAM1-like protein DUF2623 PF11115.8 KIY74030.1 - 0.18 11.9 0.3 0.34 11.0 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2623) Histone PF00125.24 KIY74031.1 - 1.4e-45 154.8 2.0 1.6e-45 154.7 2.0 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KIY74031.1 - 4.4e-05 23.6 0.0 6.2e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KIY74031.1 - 0.00018 21.8 0.2 0.00026 21.3 0.2 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KIY74031.1 - 0.0013 18.9 0.4 0.0026 18.0 0.4 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KIY74031.1 - 0.04 14.0 0.0 0.055 13.5 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit 60KD_IMP PF02096.20 KIY74032.1 - 1.1e-11 45.0 0.4 3.8e-10 39.9 0.4 2.0 1 1 0 1 1 1 1 60Kd inner membrane protein Ribosomal_L6e PF01159.19 KIY74033.1 - 2.4e-38 131.1 0.2 2.4e-38 131.1 0.2 1.5 2 0 0 2 2 2 1 Ribosomal protein L6e Ribosomal_L6e_N PF03868.15 KIY74033.1 - 1.2e-05 25.5 0.2 1.2e-05 25.5 0.2 2.5 3 0 0 3 3 3 1 Ribosomal protein L6, N-terminal domain RdRP PF05183.12 KIY74034.1 - 4.3e-115 385.6 0.0 6e-115 385.1 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase hnRNP_Q_AcD PF18360.1 KIY74034.1 - 0.11 12.5 0.0 0.29 11.1 0.0 1.7 1 0 0 1 1 1 0 Heterogeneous nuclear ribonucleoprotein Q acidic domain VWA_2 PF13519.6 KIY74036.1 - 1.7e-05 25.4 0.0 5.4e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KIY74036.1 - 0.00061 20.1 0.0 0.00093 19.5 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Questin_oxidase PF14027.6 KIY74037.1 - 6.9e-64 216.5 0.0 8.7e-64 216.2 0.0 1.0 1 0 0 1 1 1 1 Questin oxidase-like RdRP PF05183.12 KIY74038.1 - 3.8e-113 379.2 0.0 5.3e-113 378.7 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase Dcc1 PF09724.9 KIY74039.1 - 3.5e-77 260.0 0.0 4e-77 259.8 0.0 1.0 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 CUE PF02845.16 KIY74040.1 - 0.018 14.8 0.1 0.31 10.8 0.1 2.9 1 1 0 1 1 1 0 CUE domain DUF4492 PF14899.6 KIY74042.1 - 0.66 9.9 4.1 0.71 9.8 0.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4492) Mito_carr PF00153.27 KIY74043.1 - 6.6e-51 170.2 1.1 2.1e-18 66.0 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein RSN1_7TM PF02714.15 KIY74044.1 - 8e-71 238.5 15.9 8e-71 238.5 15.9 1.8 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KIY74044.1 - 1.8e-38 131.7 0.9 1.8e-38 131.7 0.9 2.2 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KIY74044.1 - 2.4e-24 86.5 0.1 4.5e-23 82.4 0.0 2.8 2 1 1 3 3 3 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 KIY74044.1 - 2.3e-14 53.3 0.0 7.2e-14 51.7 0.0 1.9 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter Clat_adaptor_s PF01217.20 KIY74045.1 - 1.3e-55 187.2 1.4 2e-55 186.6 1.4 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain adh_short PF00106.25 KIY74046.1 - 2.7e-22 79.2 0.0 5.1e-22 78.3 0.0 1.4 1 1 1 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIY74046.1 - 2.5e-20 73.0 0.1 3.4e-20 72.6 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIY74046.1 - 0.0016 18.4 0.1 0.0036 17.3 0.1 1.6 1 1 0 1 1 1 1 KR domain YjeF_N PF03853.15 KIY74046.1 - 0.0052 16.7 0.0 0.01 15.7 0.0 1.5 1 0 0 1 1 1 1 YjeF-related protein N-terminus Amidohydro_2 PF04909.14 KIY74047.1 - 1.9e-25 90.3 0.0 2.3e-25 90.0 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase Iso_dh PF00180.20 KIY74049.1 - 7.7e-78 262.1 0.0 9.4e-78 261.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DcpS PF05652.12 KIY74050.1 - 0.15 12.9 0.0 0.31 11.9 0.0 1.5 1 0 0 1 1 1 0 Scavenger mRNA decapping enzyme (DcpS) N-terminal HORMA PF02301.18 KIY74051.1 - 6.1e-57 192.6 0.0 9.5e-57 192.0 0.0 1.3 1 0 0 1 1 1 1 HORMA domain PHD PF00628.29 KIY74051.1 - 1 9.3 8.1 2.7 8.0 8.1 1.8 1 1 0 1 1 1 0 PHD-finger F-box PF00646.33 KIY74053.1 - 0.086 12.8 3.0 0.17 11.8 0.1 2.5 2 0 0 2 2 2 0 F-box domain Peptidase_M76 PF09768.9 KIY74054.1 - 3.4e-65 219.0 2.5 4.1e-65 218.7 2.5 1.0 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.9 KIY74054.1 - 0.061 13.2 0.6 0.13 12.1 0.6 1.5 1 0 0 1 1 1 0 SprT-like family DUF2268 PF10026.9 KIY74054.1 - 0.17 11.4 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) zf-C2H2_jaz PF12171.8 KIY74055.1 - 4.2e-09 36.4 1.8 6.1e-09 35.9 1.8 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KIY74055.1 - 0.014 15.7 0.1 0.022 15.1 0.1 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 KIY74055.1 - 0.12 12.8 2.4 0.22 12.0 2.4 1.4 1 0 0 1 1 1 0 Zinc-finger of C2H2 type Pkinase PF00069.25 KIY74056.1 - 2.6e-32 112.2 0.0 3.6e-32 111.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY74056.1 - 1.8e-20 73.3 0.0 2.6e-20 72.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY74056.1 - 0.00047 19.6 0.0 0.00069 19.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KIY74056.1 - 0.0014 18.0 0.0 0.0023 17.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 KIY74056.1 - 0.068 12.2 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 DUF5318 PF17249.2 KIY74056.1 - 0.15 11.8 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5318) ABC_tran PF00005.27 KIY74057.1 - 8.1e-53 178.6 0.0 6e-31 107.8 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KIY74057.1 - 2.1e-49 168.6 23.2 5.3e-28 98.4 6.7 3.3 3 0 0 3 3 3 3 ABC transporter transmembrane region SMC_N PF02463.19 KIY74057.1 - 3.6e-09 36.4 0.0 4.2e-05 23.1 0.0 3.7 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KIY74057.1 - 3.4e-07 30.4 2.0 0.17 11.7 0.1 4.3 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system T2SSE PF00437.20 KIY74057.1 - 1.9e-06 27.2 0.1 0.011 14.8 0.1 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_23 PF13476.6 KIY74057.1 - 9.8e-06 26.2 0.1 0.0029 18.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KIY74057.1 - 4.8e-05 23.0 0.6 0.4 10.5 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.6 KIY74057.1 - 0.00013 21.6 0.2 0.47 10.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KIY74057.1 - 0.00059 20.3 1.8 1.5 9.2 0.1 3.1 2 2 0 2 2 2 2 AAA ATPase domain Dynamin_N PF00350.23 KIY74057.1 - 0.0065 16.5 0.4 0.28 11.2 0.0 2.8 3 0 0 3 3 3 1 Dynamin family DUF87 PF01935.17 KIY74057.1 - 0.011 15.9 0.0 0.026 14.6 0.0 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_22 PF13401.6 KIY74057.1 - 0.014 15.7 0.3 24 5.2 0.1 3.5 3 0 0 3 3 3 0 AAA domain RsgA_GTPase PF03193.16 KIY74057.1 - 0.039 13.9 0.1 12 5.8 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase AAA_15 PF13175.6 KIY74057.1 - 0.04 13.6 0.0 2.5 7.7 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain RseC_MucC PF04246.12 KIY74057.1 - 0.049 13.6 0.0 0.23 11.4 0.0 2.2 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC MMR_HSR1 PF01926.23 KIY74057.1 - 0.058 13.5 0.2 3.2 7.9 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase ATPase_2 PF01637.18 KIY74057.1 - 0.1 12.5 0.0 0.73 9.7 0.0 2.2 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea cobW PF02492.19 KIY74057.1 - 0.14 11.8 0.5 2 7.9 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 KIY74057.1 - 0.25 11.2 1.0 6.2 6.7 0.0 2.7 2 0 0 2 2 2 0 NACHT domain adh_short PF00106.25 KIY74058.1 - 2.1e-45 154.6 0.7 2.4e-45 154.4 0.7 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIY74058.1 - 1.7e-37 129.2 0.7 2e-37 129.0 0.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIY74058.1 - 6.8e-14 52.2 1.2 1.5e-13 51.0 1.2 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KIY74058.1 - 1e-06 28.4 0.9 2.4e-05 23.9 0.9 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KIY74058.1 - 3.2e-06 27.2 1.7 4.9e-06 26.6 1.7 1.4 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KIY74058.1 - 1e-05 25.2 1.0 2.7e-05 23.9 0.9 1.6 2 0 0 2 2 2 1 NmrA-like family 3Beta_HSD PF01073.19 KIY74058.1 - 0.00093 18.3 1.0 0.0019 17.3 0.1 1.9 3 0 0 3 3 3 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.18 KIY74058.1 - 0.03 14.6 0.9 0.8 10.0 0.4 2.2 2 0 0 2 2 2 0 TrkA-N domain GDP_Man_Dehyd PF16363.5 KIY74058.1 - 0.057 12.8 0.2 0.11 11.8 0.0 1.5 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KIY74058.1 - 0.12 11.5 0.3 0.45 9.6 0.3 1.8 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein DUF2974 PF11187.8 KIY74058.1 - 0.19 11.3 0.0 2.7 7.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Transket_pyr PF02779.24 KIY74059.1 - 4.1e-48 163.4 0.0 6.7e-48 162.7 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KIY74059.1 - 7.4e-42 142.1 0.2 1.7e-41 141.0 0.2 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain PFOR_II PF17147.4 KIY74059.1 - 0.0023 18.2 0.0 0.0045 17.3 0.0 1.5 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Histidinol_dh PF00815.20 KIY74060.1 - 2.7e-166 553.6 1.5 3.6e-166 553.2 1.5 1.1 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.18 KIY74060.1 - 8.5e-24 83.2 0.1 2.5e-23 81.7 0.0 1.9 2 0 0 2 2 2 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 KIY74060.1 - 7.8e-12 45.5 0.1 1.7e-11 44.4 0.1 1.6 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase RHH_8 PF17723.1 KIY74060.1 - 0.094 12.9 0.5 7.2 6.8 0.0 2.7 2 0 0 2 2 2 0 Ribbon-Helix-Helix transcriptional regulator family AIRC PF00731.20 KIY74060.1 - 0.39 10.3 5.0 0.048 13.2 0.5 1.8 2 0 0 2 2 2 0 AIR carboxylase Snf7 PF03357.21 KIY74061.1 - 3e-31 108.3 17.3 3e-31 108.3 17.3 1.4 1 1 0 1 1 1 1 Snf7 MqsR_toxin PF15723.5 KIY74061.1 - 0.28 11.6 1.9 7.9 6.9 0.2 2.3 2 0 0 2 2 2 0 Motility quorum-sensing regulator, toxin of MqsA zf-CpG_bind_C PF12269.8 KIY74061.1 - 2.3 7.9 5.8 3.2 7.5 0.5 2.3 2 0 0 2 2 2 0 CpG binding protein zinc finger C terminal domain LUC7 PF03194.15 KIY74061.1 - 6.1 6.4 14.1 0.13 11.9 5.1 2.1 1 1 1 2 2 2 0 LUC7 N_terminus Iso_dh PF00180.20 KIY74062.1 - 7.4e-100 334.5 0.0 9.3e-100 334.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase RNB PF00773.19 KIY74063.1 - 3.9e-94 315.6 0.0 6.5e-94 314.9 0.0 1.4 1 0 0 1 1 1 1 RNB domain Dis3l2_C_term PF17877.1 KIY74063.1 - 8.5e-24 83.7 0.1 2.2e-23 82.4 0.1 1.7 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal OB_Dis3 PF17849.1 KIY74063.1 - 2e-23 82.2 0.0 5.2e-23 80.9 0.0 1.8 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) CSD2 PF17876.1 KIY74063.1 - 0.0001 22.4 0.0 0.044 13.9 0.0 2.9 2 0 0 2 2 2 2 Cold shock domain Rrp44_S1 PF17215.3 KIY74063.1 - 0.0095 15.9 0.1 0.026 14.5 0.1 1.7 1 0 0 1 1 1 1 S1 domain Rrp44_CSD1 PF17216.3 KIY74063.1 - 0.014 15.1 0.0 0.028 14.1 0.0 1.4 1 0 0 1 1 1 0 Rrp44-like cold shock domain BTB_2 PF02214.22 KIY74064.1 - 0.011 16.1 0.0 0.025 14.9 0.0 1.6 1 0 0 1 1 1 0 BTB/POZ domain Pkinase PF00069.25 KIY74065.1 - 8.8e-46 156.4 0.0 4.2e-31 108.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIY74065.1 - 5.7e-24 84.8 0.0 8.1e-24 84.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KIY74065.1 - 0.00026 19.9 0.0 0.00039 19.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KIY74065.1 - 0.0056 16.6 0.2 0.0082 16.1 0.2 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family AAA_5 PF07728.14 KIY74066.1 - 5.5e-116 382.7 0.0 3.3e-21 75.7 0.0 9.8 8 1 1 9 9 9 9 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 KIY74066.1 - 3.5e-53 178.3 1.7 2.1e-19 69.7 0.0 5.4 4 0 0 4 4 4 3 Midasin AAA lid domain AAA_3 PF07726.11 KIY74066.1 - 1.3e-28 99.5 0.0 1.3e-08 34.8 0.0 8.3 8 0 0 8 8 8 3 ATPase family associated with various cellular activities (AAA) AAA_lid_5 PF17865.1 KIY74066.1 - 9.7e-26 89.9 0.0 3e-25 88.4 0.0 1.9 1 0 0 1 1 1 1 Midasin AAA lid domain AAA PF00004.29 KIY74066.1 - 1.3e-25 90.3 0.7 0.00051 20.5 0.0 7.8 7 0 0 7 7 7 4 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KIY74066.1 - 3.5e-19 69.0 0.1 0.00034 20.2 0.1 6.2 6 0 0 6 6 6 4 P-loop containing dynein motor region Dynein_heavy PF03028.15 KIY74066.1 - 7.5e-19 68.0 0.0 0.011 15.9 0.0 6.5 5 0 0 5 5 5 4 Dynein heavy chain region D6 P-loop domain AAA_6 PF12774.7 KIY74066.1 - 3.4e-17 62.4 0.0 0.0077 15.2 0.0 6.8 7 0 0 7 7 7 4 Hydrolytic ATP binding site of dynein motor region AAA_16 PF13191.6 KIY74066.1 - 5.2e-17 62.7 26.9 0.00022 21.7 0.3 9.4 9 2 0 9 9 6 4 AAA ATPase domain AAA_18 PF13238.6 KIY74066.1 - 2.9e-15 57.0 0.0 0.019 15.5 0.0 7.4 6 0 0 6 6 6 2 AAA domain AAA_22 PF13401.6 KIY74066.1 - 3.5e-15 56.5 2.2 0.022 15.0 0.0 7.8 8 0 0 8 8 6 2 AAA domain Sigma54_activat PF00158.26 KIY74066.1 - 1.1e-14 54.4 0.0 0.049 13.3 0.0 6.0 6 0 0 6 6 6 3 Sigma-54 interaction domain AAA_14 PF13173.6 KIY74066.1 - 1.9e-13 50.5 0.0 0.52 10.4 0.0 7.2 7 0 0 7 7 6 3 AAA domain TsaE PF02367.17 KIY74066.1 - 1e-12 48.2 0.8 0.26 11.3 0.0 6.3 6 0 0 6 6 6 3 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 KIY74066.1 - 5.1e-12 45.9 0.0 0.13 12.0 0.0 7.5 7 1 0 7 7 7 2 AAA domain T2SSE PF00437.20 KIY74066.1 - 7.9e-11 41.5 0.1 0.09 11.8 0.0 5.8 6 0 0 6 6 6 3 Type II/IV secretion system protein RNA_helicase PF00910.22 KIY74066.1 - 1.6e-09 38.1 0.1 0.47 10.9 0.0 6.5 6 0 0 6 6 6 1 RNA helicase Sigma54_activ_2 PF14532.6 KIY74066.1 - 4.8e-09 36.5 0.1 0.0015 18.7 0.0 4.6 4 0 0 4 4 4 2 Sigma-54 interaction domain AAA_19 PF13245.6 KIY74066.1 - 4e-08 33.7 3.8 0.41 11.0 0.0 6.1 5 0 0 5 5 5 1 AAA domain AAA_28 PF13521.6 KIY74066.1 - 5.2e-08 33.3 18.9 2.2 8.5 0.1 8.0 8 0 0 8 8 7 1 AAA domain ABC_tran PF00005.27 KIY74066.1 - 9.5e-08 32.6 2.6 0.96 10.0 0.0 6.6 7 0 0 7 7 5 2 ABC transporter RuvB_N PF05496.12 KIY74066.1 - 4.4e-07 29.8 2.3 0.88 9.3 0.0 6.2 7 0 0 7 7 6 1 Holliday junction DNA helicase RuvB P-loop domain Zeta_toxin PF06414.12 KIY74066.1 - 6.6e-07 28.8 0.1 0.4 9.9 0.0 5.8 7 0 0 7 7 5 1 Zeta toxin NACHT PF05729.12 KIY74066.1 - 1.8e-06 28.0 4.3 1.2 9.0 0.0 5.4 6 0 0 6 6 4 1 NACHT domain DUF815 PF05673.13 KIY74066.1 - 6.4e-06 25.5 0.0 1.5 7.9 0.0 4.4 5 0 0 5 5 5 1 Protein of unknown function (DUF815) AAA_25 PF13481.6 KIY74066.1 - 9.1e-06 25.4 6.4 2.7 7.5 0.0 6.0 7 0 0 7 7 5 1 AAA domain AAA_33 PF13671.6 KIY74066.1 - 1.2e-05 25.5 5.7 1.6 8.9 0.0 6.6 7 0 0 7 7 6 1 AAA domain Mg_chelatase PF01078.21 KIY74066.1 - 2e-05 24.1 3.0 25 4.1 0.0 7.2 8 0 0 8 8 7 0 Magnesium chelatase, subunit ChlI Roc PF08477.13 KIY74066.1 - 4.9e-05 23.5 1.1 11 6.3 0.0 5.6 6 0 0 6 6 5 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 KIY74066.1 - 0.00011 21.9 1.3 3.2 7.6 0.1 5.3 6 0 0 6 6 4 1 P-loop containing region of AAA domain AAA_24 PF13479.6 KIY74066.1 - 0.00011 21.9 0.1 8.9 6.0 0.0 5.4 5 0 0 5 5 5 0 AAA domain Rad17 PF03215.15 KIY74066.1 - 0.00013 21.9 0.7 7.9 6.4 0.0 5.7 6 0 0 6 6 6 0 Rad17 P-loop domain IstB_IS21 PF01695.17 KIY74066.1 - 0.00015 21.6 0.2 3.4 7.4 0.0 4.6 5 0 0 5 5 4 1 IstB-like ATP binding protein CbiA PF01656.23 KIY74066.1 - 0.00029 20.9 0.1 3 7.9 0.2 5.1 4 1 0 4 4 4 1 CobQ/CobB/MinD/ParA nucleotide binding domain RsgA_GTPase PF03193.16 KIY74066.1 - 0.00043 20.2 0.3 1.7 8.5 0.0 4.1 3 0 0 3 3 3 1 RsgA GTPase ResIII PF04851.15 KIY74066.1 - 0.00057 19.9 0.0 7.2 6.6 0.0 5.1 5 0 0 5 5 5 0 Type III restriction enzyme, res subunit SRP54 PF00448.22 KIY74066.1 - 0.00067 19.3 0.5 7.8 6.1 0.0 5.2 6 0 0 6 6 5 0 SRP54-type protein, GTPase domain cobW PF02492.19 KIY74066.1 - 0.0011 18.6 1.2 3.1 7.3 0.0 4.1 4 0 0 4 4 4 1 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 KIY74066.1 - 0.0029 17.7 0.8 15 5.7 0.0 5.4 7 0 0 7 7 5 0 50S ribosome-binding GTPase TniB PF05621.11 KIY74066.1 - 0.0053 16.2 0.0 2.1 7.7 0.0 4.5 6 0 0 6 6 5 1 Bacterial TniB protein PduV-EutP PF10662.9 KIY74066.1 - 0.0065 16.2 3.2 0.34 10.6 0.0 4.1 5 0 0 5 5 4 1 Ethanolamine utilisation - propanediol utilisation Viral_helicase1 PF01443.18 KIY74066.1 - 0.0074 16.0 0.2 0.28 10.9 0.0 3.5 4 0 0 4 4 3 1 Viral (Superfamily 1) RNA helicase VWA PF00092.28 KIY74066.1 - 0.0087 16.3 0.7 0.025 14.8 0.7 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain TIP49 PF06068.13 KIY74066.1 - 0.026 13.7 0.1 8.1 5.5 0.0 3.7 4 0 0 4 4 4 0 TIP49 P-loop domain AAA_8 PF12780.7 KIY74066.1 - 0.026 13.9 0.0 5.8 6.1 0.0 4.0 4 0 0 4 4 3 0 P-loop containing dynein motor region D4 dNK PF01712.19 KIY74066.1 - 0.034 14.0 0.6 14 5.4 0.0 4.3 5 0 0 5 5 5 0 Deoxynucleoside kinase IPT PF01745.16 KIY74066.1 - 0.06 12.7 0.1 30 3.9 0.0 3.6 3 0 0 3 3 3 0 Isopentenyl transferase NTPase_1 PF03266.15 KIY74066.1 - 0.073 13.0 7.4 8.4 6.3 0.1 4.8 5 0 0 5 5 5 0 NTPase PRK PF00485.18 KIY74066.1 - 0.089 12.5 0.1 5.1 6.8 0.0 2.7 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family SRPRB PF09439.10 KIY74066.1 - 0.098 12.1 2.2 27 4.2 0.0 4.8 6 0 0 6 6 5 0 Signal recognition particle receptor beta subunit ATPase PF06745.13 KIY74066.1 - 0.38 10.1 1.6 17 4.6 0.0 3.2 3 0 0 3 3 2 0 KaiC VID27 PF08553.10 KIY74067.1 - 6.3e-164 545.2 0.2 8.5e-164 544.8 0.2 1.1 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain VID27_N PF17748.1 KIY74067.1 - 3.1e-54 183.4 0.1 3.1e-54 183.4 0.1 3.3 2 1 1 3 3 3 2 VID27 N-terminal region VID27_PH PF17747.1 KIY74067.1 - 5e-19 68.6 0.3 1.3e-18 67.2 0.3 1.8 1 0 0 1 1 1 1 VID27 PH-like domain Fes1 PF08609.10 KIY74069.1 - 7.9e-22 77.9 2.8 7.9e-22 77.9 2.8 2.6 3 0 0 3 3 3 1 Nucleotide exchange factor Fes1 SIL1 PF16782.5 KIY74069.1 - 2.1e-05 23.9 0.5 4.1e-05 22.9 0.5 1.6 1 1 0 1 1 1 1 Nucleotide exchange factor SIL1 HEAT PF02985.22 KIY74069.1 - 0.00033 20.6 0.1 0.27 11.6 0.1 3.1 3 0 0 3 3 3 1 HEAT repeat HEAT_2 PF13646.6 KIY74069.1 - 0.0006 20.2 0.0 0.0017 18.7 0.0 1.8 1 0 0 1 1 1 1 HEAT repeats Cnd1 PF12717.7 KIY74069.1 - 0.00071 19.7 0.0 0.0031 17.6 0.0 2.1 1 1 1 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KIY74069.1 - 0.0028 18.1 0.4 4.2 8.0 0.1 3.1 2 1 0 2 2 2 2 HEAT-like repeat V-ATPase_H_N PF03224.14 KIY74069.1 - 0.026 13.8 1.1 0.083 12.2 0.7 1.6 1 1 1 2 2 2 0 V-ATPase subunit H IFRD PF05004.13 KIY74069.1 - 0.051 12.7 0.3 0.2 10.7 0.1 2.1 1 1 0 1 1 1 0 Interferon-related developmental regulator (IFRD) RPA_C PF08784.11 KIY74070.1 - 0.14 12.8 0.0 0.35 11.5 0.0 1.6 1 0 0 1 1 1 0 Replication protein A C terminal ORC6 PF05460.13 KIY74070.1 - 2.6 7.2 26.9 0.74 9.0 0.0 3.1 2 1 1 3 3 3 0 Origin recognition complex subunit 6 (ORC6) CHAT PF12770.7 KIY74071.1 - 5.3e-36 124.5 0.0 1.3e-35 123.2 0.0 1.6 2 0 0 2 2 2 1 CHAT domain TPR_19 PF14559.6 KIY74071.1 - 0.011 16.2 0.3 0.26 11.8 0.0 3.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 KIY74071.1 - 0.028 14.3 7.6 16 5.5 0.0 5.9 7 0 0 7 7 7 0 Tetratricopeptide repeat MARVEL PF01284.23 KIY74072.1 - 0.00055 20.0 5.6 0.00065 19.8 5.6 1.1 1 0 0 1 1 1 1 Membrane-associating domain PGG PF13962.6 KIY74072.1 - 0.085 12.7 2.6 0.1 12.4 1.7 1.5 2 0 0 2 2 2 0 Domain of unknown function DUF3810 PF12725.7 KIY74072.1 - 1.6 8.0 4.1 1.3 8.3 2.5 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3810) DEAD PF00270.29 KIY74073.1 - 1.3e-46 158.5 0.0 2.5e-46 157.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIY74073.1 - 2e-31 108.6 0.1 1.6e-30 105.7 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIY74073.1 - 2.7e-06 27.5 0.0 5.2e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KIY74073.1 - 0.052 13.9 0.1 0.28 11.5 0.0 2.4 2 1 0 2 2 2 0 AAA domain ATP-grasp_6 PF18419.1 KIY74073.1 - 0.056 13.1 0.0 0.65 9.7 0.0 2.6 2 0 0 2 2 2 0 ATP-grasp-like domain FAD_binding_2 PF00890.24 KIY74074.1 - 1.2e-81 275.0 4.9 1.3e-81 274.8 4.9 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KIY74074.1 - 1.6e-12 47.7 5.2 5.8e-12 45.9 3.2 2.3 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KIY74074.1 - 1.7e-08 34.1 0.5 3.3e-08 33.1 0.2 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KIY74074.1 - 2.3e-08 33.8 3.0 4.9e-08 32.7 3.0 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KIY74074.1 - 2.6e-08 34.0 0.5 9.1e-08 32.2 0.5 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KIY74074.1 - 3.9e-07 29.1 6.9 3.7e-06 25.9 0.6 3.0 3 0 0 3 3 3 1 HI0933-like protein GIDA PF01134.22 KIY74074.1 - 7.7e-07 28.5 8.0 6.4e-06 25.5 0.8 2.5 3 0 0 3 3 3 2 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 KIY74074.1 - 9.1e-05 21.9 0.4 0.00016 21.1 0.4 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 KIY74074.1 - 0.00015 21.2 0.9 0.00023 20.5 0.9 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KIY74074.1 - 0.0032 16.8 1.7 0.01 15.1 0.5 2.1 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.6 KIY74074.1 - 0.0055 16.0 0.1 0.21 10.8 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KIY74074.1 - 0.015 14.4 0.5 0.025 13.6 0.5 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.27 KIY74074.1 - 0.077 13.6 2.5 0.32 11.6 0.4 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KIY74074.1 - 0.082 13.4 0.0 0.21 12.1 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding dCache_1 PF02743.18 KIY74074.1 - 0.14 11.9 0.1 4.6 6.9 0.0 2.2 2 0 0 2 2 2 0 Cache domain Hva1_TUDOR PF11160.8 KIY74075.1 - 1.6e-15 57.0 3.7 1.8e-15 56.8 3.7 1.1 1 0 0 1 1 1 1 Hypervirulence associated proteins TUDOR domain ProQ_C PF17516.2 KIY74075.1 - 0.0053 16.1 0.6 0.0077 15.6 0.6 1.3 1 0 0 1 1 1 1 ProQ C-terminal domain DUF202 PF02656.15 KIY74076.1 - 1.5e-15 57.3 2.3 1.5e-15 57.3 2.3 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF202) DUF202 PF02656.15 KIY74077.1 - 1.8e-14 54.0 0.2 1.8e-14 54.0 0.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF202) zf-RING_2 PF13639.6 KIY74078.1 - 9.8e-13 48.2 4.4 1.5e-12 47.6 4.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KIY74078.1 - 3.9e-09 36.2 4.1 6.1e-09 35.6 4.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KIY74078.1 - 4.2e-09 36.0 1.4 7.5e-09 35.2 1.4 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 KIY74078.1 - 2.7e-08 34.0 5.0 4.8e-08 33.2 5.0 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KIY74078.1 - 8e-08 32.0 2.9 1.2e-07 31.4 2.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIY74078.1 - 1.8e-07 31.0 2.5 2.7e-07 30.4 2.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KIY74078.1 - 2.7e-05 23.9 2.8 4.6e-05 23.2 2.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KIY74078.1 - 0.00016 21.6 1.6 0.00032 20.7 1.6 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 KIY74078.1 - 0.00093 19.2 3.4 0.0017 18.3 3.4 1.4 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KIY74078.1 - 0.0015 18.4 2.1 0.0025 17.6 2.1 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 KIY74078.1 - 0.008 15.8 5.4 0.013 15.1 5.4 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type RINGv PF12906.7 KIY74078.1 - 0.062 13.4 4.0 0.11 12.7 4.0 1.4 1 0 0 1 1 1 0 RING-variant domain PHD PF00628.29 KIY74078.1 - 0.29 11.0 3.7 0.48 10.4 3.7 1.4 1 0 0 1 1 1 0 PHD-finger DUF1272 PF06906.11 KIY74078.1 - 0.58 10.3 4.9 1.3 9.2 4.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) FANCL_C PF11793.8 KIY74078.1 - 1.7 8.9 4.6 3 8.1 4.6 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.11 KIY74078.1 - 1.8 9.0 6.5 3.2 8.1 6.5 1.4 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.6 KIY74078.1 - 9.8 6.1 10.5 0.91 9.4 5.6 1.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain F-box-like PF12937.7 KIY74079.1 - 3.1e-07 30.2 1.5 3e-05 23.8 0.7 2.9 2 1 0 2 2 2 2 F-box-like CALCOCO1 PF07888.11 KIY74079.1 - 0.21 10.4 0.0 0.28 10.0 0.0 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like UTP25 PF06862.12 KIY74080.1 - 4.3e-160 533.6 0.0 5.2e-160 533.3 0.0 1.1 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DUF218 PF02698.17 KIY74080.1 - 0.065 13.3 0.3 5.7 7.0 0.1 3.0 2 1 0 2 2 2 0 DUF218 domain Topoisom_bac PF01131.20 KIY74081.1 - 1.3e-110 370.3 0.1 1.5e-110 370.0 0.1 1.1 1 0 0 1 1 1 1 DNA topoisomerase zf-GRF PF06839.12 KIY74081.1 - 2.1e-25 88.6 14.3 4.1e-14 52.4 2.7 2.9 2 0 0 2 2 2 2 GRF zinc finger Toprim PF01751.22 KIY74081.1 - 1.1e-17 64.1 0.0 6.5e-17 61.6 0.0 2.1 2 0 0 2 2 2 1 Toprim domain zf-CCHC PF00098.23 KIY74081.1 - 1.3e-14 53.5 23.9 3.3e-05 23.8 2.8 3.6 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_3 PF13917.6 KIY74081.1 - 7.8e-10 38.6 11.4 0.004 17.1 0.2 4.5 4 0 0 4 4 4 3 Zinc knuckle eIF3g PF12353.8 KIY74081.1 - 7.4e-05 23.1 8.3 0.65 10.4 0.2 3.6 3 0 0 3 3 3 3 Eukaryotic translation initiation factor 3 subunit G zf-CCHC_2 PF13696.6 KIY74081.1 - 0.024 14.4 17.8 0.22 11.4 1.7 3.6 3 0 0 3 3 3 0 Zinc knuckle zf-CCHC_5 PF14787.6 KIY74081.1 - 0.51 10.1 15.0 6.2 6.6 0.6 3.6 3 0 0 3 3 3 0 GAG-polyprotein viral zinc-finger PI3_PI4_kinase PF00454.27 KIY74085.1 - 5e-36 124.8 0.0 9.3e-36 123.9 0.0 1.5 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase zf-ANAPC11 PF12861.7 KIY74087.1 - 8.6e-40 134.7 9.9 9.8e-40 134.5 9.9 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KIY74087.1 - 2.1e-21 76.0 12.4 2.7e-21 75.6 12.4 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KIY74087.1 - 3.2e-05 24.2 15.7 0.00056 20.2 15.7 2.4 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KIY74087.1 - 0.0083 16.0 5.3 0.0083 16.0 5.3 2.5 2 2 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIY74087.1 - 0.03 14.2 14.1 0.15 12.0 14.0 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KIY74087.1 - 0.034 13.8 12.0 0.085 12.5 12.0 1.7 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 KIY74087.1 - 0.048 13.7 12.1 0.1 12.6 12.1 1.5 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 KIY74087.1 - 0.12 12.4 13.6 0.57 10.2 13.6 2.3 1 1 0 1 1 1 0 zinc-RING finger domain RINGv PF12906.7 KIY74087.1 - 1.5 9.0 11.4 9.1 6.5 11.5 2.2 1 1 1 2 2 2 0 RING-variant domain zf-RING_11 PF17123.5 KIY74087.1 - 3 7.7 13.6 25 4.7 13.6 2.2 1 1 0 1 1 1 0 RING-like zinc finger zf-RING-like PF08746.11 KIY74087.1 - 9.7 6.6 12.7 44 4.5 12.7 2.2 1 1 0 1 1 1 0 RING-like domain Glyco_hydro_18 PF00704.28 KIY74088.1 - 5.1e-54 184.1 0.0 6.2e-54 183.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Op_neuropeptide PF08035.11 KIY74088.1 - 0.17 11.8 0.0 0.54 10.2 0.0 1.8 1 0 0 1 1 1 0 Opioids neuropeptide DUF5127 PF17168.4 KIY74089.1 - 1.4e-78 263.8 5.9 2.1e-78 263.2 5.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 KIY74089.1 - 9.2e-77 256.6 0.4 1.6e-76 255.8 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 KIY74089.1 - 8.4e-64 215.0 1.3 2e-63 213.8 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 KIY74089.1 - 1.2e-11 44.0 0.0 3.8e-11 42.4 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) PhrC_PhrF PF11131.8 KIY74091.1 - 0.96 9.1 5.5 0.63 9.7 2.1 2.2 2 0 0 2 2 2 0 Rap-phr extracellular signalling Wtap PF17098.5 KIY74092.1 - 4.6e-12 46.1 7.5 2.6e-10 40.4 2.6 2.3 1 1 1 2 2 2 2 WTAP/Mum2p family HAP1_N PF04849.13 KIY74092.1 - 0.0074 15.5 6.1 0.035 13.3 6.1 2.0 1 1 0 1 1 1 1 HAP1 N-terminal conserved region ATG16 PF08614.11 KIY74092.1 - 0.018 15.3 1.5 0.018 15.3 1.5 3.2 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) NPV_P10 PF05531.12 KIY74092.1 - 0.024 15.1 2.1 0.64 10.5 0.7 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Cep57_MT_bd PF06657.13 KIY74092.1 - 0.038 14.4 5.6 4.2 7.9 0.9 4.3 3 1 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 FliJ PF02050.16 KIY74092.1 - 0.059 13.6 0.9 0.9 9.8 0.2 2.5 3 0 0 3 3 3 0 Flagellar FliJ protein bZIP_1 PF00170.21 KIY74092.1 - 0.067 13.3 7.5 0.28 11.3 1.2 3.3 2 1 1 3 3 3 0 bZIP transcription factor Baculo_F PF12259.8 KIY74092.1 - 0.1 11.1 1.9 2.1 6.8 0.0 2.1 2 0 0 2 2 2 0 Baculovirus F protein Bacillus_HBL PF05791.11 KIY74092.1 - 0.13 12.1 2.4 0.17 11.7 0.5 1.9 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) E2F_CC-MB PF16421.5 KIY74092.1 - 0.18 12.2 3.2 1.5 9.2 0.1 2.9 3 0 0 3 3 3 0 E2F transcription factor CC-MB domain CtIP_N PF10482.9 KIY74092.1 - 0.37 10.8 4.3 9.8 6.3 0.1 3.3 2 1 1 3 3 3 0 Tumour-suppressor protein CtIP N-terminal domain DUF1664 PF07889.12 KIY74092.1 - 0.38 10.8 2.3 0.95 9.5 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) YlbD_coat PF14071.6 KIY74092.1 - 0.4 10.9 3.3 14 6.0 0.1 2.3 2 0 0 2 2 2 0 Putative coat protein SKA1 PF07160.12 KIY74092.1 - 0.41 10.5 8.5 0.46 10.3 7.2 1.8 2 1 0 2 2 2 0 Spindle and kinetochore-associated protein 1 YojJ PF10372.9 KIY74092.1 - 0.47 10.6 1.8 0.57 10.3 0.5 1.8 2 0 0 2 2 1 0 Bacterial membrane-spanning protein N-terminus WD40_alt PF14077.6 KIY74092.1 - 0.71 9.8 3.3 29 4.6 0.1 3.3 2 1 1 3 3 3 0 Alternative WD40 repeat motif DUF4407 PF14362.6 KIY74092.1 - 0.88 8.9 7.7 7.4 5.8 7.8 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) PKcGMP_CC PF16808.5 KIY74092.1 - 0.9 9.4 4.0 1.9 8.4 0.8 2.6 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase MbeD_MobD PF04899.12 KIY74092.1 - 1.9 8.7 4.3 35 4.6 0.6 3.1 2 1 1 3 3 3 0 MbeD/MobD like UPF0242 PF06785.11 KIY74092.1 - 2.3 8.3 8.0 9.7 6.2 0.7 2.6 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus HALZ PF02183.18 KIY74092.1 - 4.7 7.5 6.9 5.1 7.4 0.2 3.5 3 1 1 4 4 4 0 Homeobox associated leucine zipper Helo_like_N PF17111.5 KIY74092.1 - 7.1 5.9 7.3 0.69 9.2 0.3 2.4 3 0 0 3 3 3 0 Fungal N-terminal domain of STAND proteins TMF_DNA_bd PF12329.8 KIY74092.1 - 7.6 6.6 11.0 6.5 6.8 0.7 3.4 3 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding PRKG1_interact PF15898.5 KIY74092.1 - 9.6 7.2 12.6 0.29 12.0 2.0 3.0 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain Ank_2 PF12796.7 KIY74094.1 - 2.7e-19 69.5 0.0 1.1e-11 45.1 0.0 2.7 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KIY74094.1 - 2.3e-17 63.1 0.1 1e-09 38.7 0.0 4.3 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KIY74094.1 - 1.3e-15 57.2 0.2 7.6e-09 35.7 0.1 3.8 2 2 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KIY74094.1 - 1.8e-12 46.2 0.0 0.0011 19.2 0.0 4.8 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 KIY74094.1 - 1.4e-11 44.3 0.2 0.00024 21.4 0.0 3.5 4 0 0 4 4 4 2 Ankyrin repeat Fes1 PF08609.10 KIY74094.1 - 0.082 13.8 0.1 0.27 12.1 0.1 1.9 1 0 0 1 1 1 0 Nucleotide exchange factor Fes1 MFS_2 PF13347.6 KIY74095.1 - 1.1e-05 24.3 5.7 1.1e-05 24.3 5.7 2.7 2 1 0 2 2 2 1 MFS/sugar transport protein ETRAMP PF09716.10 KIY74095.1 - 0.12 12.4 0.0 2.5 8.2 0.1 2.6 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) HEAT_2 PF13646.6 KIY74096.1 - 1.1e-20 73.8 27.8 0.0035 17.7 0.0 13.2 12 2 0 12 12 12 6 HEAT repeats Gcn1_N PF12074.8 KIY74096.1 - 4.1e-17 62.5 2.8 1.6e-12 47.4 0.2 3.4 3 0 0 3 3 3 2 Generalcontrol nonderepressible 1 (Gcn1) N-terminal HEAT PF02985.22 KIY74096.1 - 5.2e-17 60.5 19.7 0.0077 16.4 0.1 15.1 16 0 0 16 16 16 3 HEAT repeat HEAT_EZ PF13513.6 KIY74096.1 - 2.3e-13 50.3 30.4 0.32 11.5 0.0 14.7 16 0 0 16 16 16 4 HEAT-like repeat CLASP_N PF12348.8 KIY74096.1 - 1.5e-07 31.2 0.0 0.0024 17.5 0.0 5.4 6 0 0 6 6 6 1 CLASP N terminal UME PF08064.13 KIY74096.1 - 7.3e-05 22.6 0.0 12 5.9 0.0 6.6 6 1 0 6 6 6 1 UME (NUC010) domain RIX1 PF08167.12 KIY74096.1 - 0.047 13.4 0.0 32 4.2 0.0 3.8 3 0 0 3 3 3 0 rRNA processing/ribosome biogenesis HEAT_PBS PF03130.16 KIY74096.1 - 0.089 13.5 4.2 68 4.6 0.1 6.6 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat MMS19_C PF12460.8 KIY74096.1 - 0.14 11.2 0.0 9 5.3 0.0 3.7 4 0 0 4 4 4 0 RNAPII transcription regulator C-terminal SKI PF01202.22 KIY74097.1 - 9.3e-14 51.8 0.0 1.1e-13 51.6 0.0 1.1 1 0 0 1 1 1 1 Shikimate kinase AAA_33 PF13671.6 KIY74097.1 - 1.9e-09 37.8 0.0 2.9e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KIY74097.1 - 7.8e-06 26.5 0.2 2.6e-05 24.8 0.2 1.9 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 KIY74097.1 - 7e-05 23.3 0.0 0.00012 22.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KIY74097.1 - 0.0004 20.8 0.2 0.0012 19.2 0.1 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.20 KIY74097.1 - 0.00058 19.8 0.0 0.00068 19.6 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase dNK PF01712.19 KIY74097.1 - 0.0011 18.8 0.2 1.5 8.6 0.0 2.1 2 0 0 2 2 2 2 Deoxynucleoside kinase AAA_22 PF13401.6 KIY74097.1 - 0.0051 17.1 0.5 0.0085 16.4 0.5 1.7 1 1 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.6 KIY74097.1 - 0.0053 16.9 0.0 0.019 15.1 0.0 1.8 2 0 0 2 2 2 1 Cytidylate kinase-like family AAA_16 PF13191.6 KIY74097.1 - 0.0063 16.9 0.2 0.012 15.9 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.6 KIY74097.1 - 0.014 15.6 0.3 0.033 14.4 0.1 1.7 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 KIY74097.1 - 0.039 13.9 0.0 0.079 12.9 0.0 1.5 2 0 0 2 2 2 0 RsgA GTPase DUF2075 PF09848.9 KIY74097.1 - 0.053 12.8 0.0 0.053 12.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Cytidylate_kin PF02224.18 KIY74097.1 - 0.056 13.2 0.0 0.11 12.2 0.0 1.6 2 0 0 2 2 2 0 Cytidylate kinase DUF736 PF05284.12 KIY74097.1 - 0.092 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF736) AAA_24 PF13479.6 KIY74097.1 - 0.14 11.9 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF4256 PF14066.6 KIY74097.1 - 0.14 11.8 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4256) SRP54 PF00448.22 KIY74097.1 - 0.27 10.8 2.3 1.4 8.5 1.0 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Sugar_tr PF00083.24 KIY74098.1 - 3.3e-124 415.2 25.9 1.6e-123 413.0 25.9 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY74098.1 - 1.2e-14 54.0 41.8 3.6e-09 36.0 17.8 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2530 PF10745.9 KIY74098.1 - 4.1 7.7 8.3 0.21 11.9 0.6 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2530) SelK_SelG PF10961.8 KIY74098.1 - 7.2 7.3 11.0 9.8 6.9 0.5 4.1 3 1 1 4 4 4 0 Selenoprotein SelK_SelG Sugar_tr PF00083.24 KIY74099.1 - 2.5e-125 418.9 27.8 3e-124 415.3 27.8 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY74099.1 - 1e-13 50.9 42.4 7.7e-09 34.9 16.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily SelK_SelG PF10961.8 KIY74099.1 - 1.9 9.2 4.4 5.4 7.7 0.4 3.1 3 0 0 3 3 3 0 Selenoprotein SelK_SelG DUF2530 PF10745.9 KIY74099.1 - 3.6 7.9 8.1 0.35 11.1 0.5 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2530) tRNA_synthFbeta PF17759.1 KIY74100.1 - 5.5e-49 166.5 0.0 8.4e-49 165.9 0.0 1.3 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 KIY74100.1 - 6.6e-31 106.4 0.1 1.6e-30 105.1 0.1 1.7 1 0 0 1 1 1 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 KIY74100.1 - 1e-26 93.7 0.1 1.9e-26 92.8 0.1 1.5 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 KIY74100.1 - 5.8e-17 61.7 0.0 1.5e-14 54.1 0.0 2.7 2 0 0 2 2 2 1 tRNA synthetase B5 domain tRNA-synt_2d PF01409.20 KIY74100.1 - 0.0014 18.2 0.0 0.0048 16.4 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetases class II core domain (F) Diphthami_syn_2 PF01902.17 KIY74101.1 - 3.4e-39 134.6 0.0 5.8e-37 127.3 0.0 2.2 1 1 0 1 1 1 1 Diphthamide synthase Ribonuc_L-PSP PF01042.21 KIY74101.1 - 3.5e-20 72.2 0.0 3.7e-10 39.9 0.0 2.7 2 1 0 2 2 2 2 Endoribonuclease L-PSP zf-MYND PF01753.18 KIY74102.1 - 2.6e-08 33.8 6.5 5.4e-08 32.8 6.5 1.6 1 0 0 1 1 1 1 MYND finger Rpr2 PF04032.16 KIY74103.1 - 3.6e-23 81.7 1.0 5.2e-23 81.1 1.0 1.2 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Mut7-C PF01927.16 KIY74103.1 - 0.0058 16.7 0.2 0.0074 16.4 0.2 1.2 1 0 0 1 1 1 1 Mut7-C RNAse domain DUF3060 PF11259.8 KIY74103.1 - 0.12 12.0 0.1 0.23 11.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3060) zinc_ribbon_12 PF11331.8 KIY74103.1 - 0.12 12.2 0.4 13 5.7 0.0 2.4 2 0 0 2 2 2 0 Probable zinc-ribbon domain AMP-binding PF00501.28 KIY74104.1 - 3.8e-72 243.2 0.0 4.7e-72 242.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KIY74104.1 - 1.2e-08 35.8 0.1 3.1e-08 34.5 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain HTH_3 PF01381.22 KIY74104.1 - 0.12 12.4 0.3 0.48 10.5 0.1 2.0 2 0 0 2 2 2 0 Helix-turn-helix Cortex-I_coil PF09304.10 KIY74105.1 - 0.21 11.8 7.3 0.35 11.1 5.6 2.3 1 1 0 1 1 1 0 Cortexillin I, coiled coil MCD_N PF17408.2 KIY74105.1 - 0.7 10.1 5.3 0.53 10.5 0.4 3.1 2 1 1 3 3 3 0 Malonyl-CoA decarboxylase N-terminal domain Atg14 PF10186.9 KIY74105.1 - 5.2 6.1 11.0 6.9 5.7 9.7 1.9 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 p450 PF00067.22 KIY74106.1 - 6.7e-54 183.4 0.0 8.8e-54 183.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Auxin_repressed PF05564.12 KIY74106.1 - 0.041 14.6 0.0 0.13 13.0 0.0 1.7 2 0 0 2 2 2 0 Dormancy/auxin associated protein DUF676 PF05057.14 KIY74107.1 - 5e-06 26.2 0.0 7.9e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF900 PF05990.12 KIY74107.1 - 0.0012 18.4 0.0 0.039 13.4 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) PGAP1 PF07819.13 KIY74107.1 - 0.0081 15.9 0.1 0.017 14.8 0.1 1.6 1 1 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.8 KIY74107.1 - 0.0087 15.3 0.1 0.021 14.1 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Lipase_3 PF01764.25 KIY74107.1 - 0.0092 15.9 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) LCAT PF02450.15 KIY74107.1 - 0.019 14.2 0.0 0.025 13.8 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Abhydrolase_3 PF07859.13 KIY74107.1 - 0.02 14.7 0.1 0.029 14.2 0.1 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 KIY74107.1 - 0.024 13.6 0.0 0.031 13.2 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme LIDHydrolase PF10230.9 KIY74107.1 - 0.043 13.4 0.0 0.068 12.7 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 KIY74107.1 - 0.059 14.0 9.4 0.13 12.8 9.4 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF915 PF06028.11 KIY74107.1 - 0.15 11.3 0.0 7.3 5.8 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) DUF2974 PF11187.8 KIY74107.1 - 0.22 11.0 0.0 0.35 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Acetyltransf_1 PF00583.25 KIY74108.1 - 2.7e-12 47.0 0.0 3.2e-12 46.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KIY74108.1 - 1e-09 38.4 0.2 1.2e-09 38.2 0.2 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KIY74108.1 - 7.1e-07 29.6 0.1 9.7e-07 29.1 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIY74108.1 - 1.3e-05 25.1 0.1 1.7e-05 24.7 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 KIY74108.1 - 0.00032 20.8 0.1 0.0004 20.5 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 KIY74108.1 - 0.00054 19.5 0.3 0.00075 19.0 0.3 1.2 1 0 0 1 1 1 1 Putative acetyl-transferase SesA PF17107.5 KIY74109.1 - 0.01 16.1 1.2 12 6.1 0.5 3.1 2 1 1 3 3 3 1 N-terminal domain on NACHT_NTPase and P-loop NTPases NPV_P10 PF05531.12 KIY74109.1 - 0.039 14.4 0.4 4.5 7.8 0.0 3.0 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein CREPT PF16566.5 KIY74109.1 - 0.19 11.9 6.7 0.66 10.1 6.2 2.2 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour ISG65-75 PF11727.8 KIY74109.1 - 0.36 10.0 4.7 0.23 10.6 2.4 1.7 2 0 0 2 2 2 0 Invariant surface glycoprotein COG2 PF06148.11 KIY74109.1 - 0.53 10.4 4.2 8.7 6.4 1.7 2.9 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 FlaC_arch PF05377.11 KIY74109.1 - 0.85 10.1 3.2 48 4.4 0.1 3.2 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) DivIVA PF05103.13 KIY74109.1 - 2.7 8.1 10.6 9.3 6.3 5.2 2.8 2 1 1 3 3 3 0 DivIVA protein SlyX PF04102.12 KIY74109.1 - 4.7 7.9 7.1 2.9 8.6 0.9 3.1 2 1 1 3 3 3 0 SlyX F-box-like PF12937.7 KIY74110.1 - 0.012 15.4 0.1 0.031 14.2 0.1 1.7 1 0 0 1 1 1 0 F-box-like Arf PF00025.21 KIY74111.1 - 1.1e-66 223.7 0.0 1.2e-66 223.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KIY74111.1 - 4.6e-10 39.2 0.0 8.4e-07 28.5 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 KIY74111.1 - 1.5e-09 37.6 0.0 1.9e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 KIY74111.1 - 2.4e-07 31.0 0.0 5.6e-07 29.8 0.0 1.6 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KIY74111.1 - 4e-07 30.1 0.0 7.1e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 KIY74111.1 - 1.4e-05 24.7 0.0 2.5e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KIY74111.1 - 7.4e-05 22.2 0.0 9e-05 21.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 KIY74111.1 - 0.082 12.7 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 KIY74111.1 - 0.11 12.0 0.0 4.2 6.9 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain FeoB_N PF02421.18 KIY74111.1 - 0.23 11.0 0.0 9.1 5.8 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B Mannosyl_trans PF05007.13 KIY74112.1 - 7.1e-71 239.1 18.0 9.4e-71 238.7 18.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.13 KIY74112.1 - 8.2e-09 35.0 20.3 5.6e-08 32.2 20.3 1.9 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U DUF3619 PF12279.8 KIY74112.1 - 0.12 12.7 0.1 0.47 10.8 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) DUF5587 PF17825.1 KIY74113.1 - 0.0012 16.3 0.0 0.0017 15.8 0.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5587) DUF4336 PF14234.6 KIY74114.1 - 1.7e-14 53.7 0.1 6.5e-09 35.4 0.0 2.7 2 1 0 2 2 2 2 Domain of unknown function (DUF4336) Vps52 PF04129.12 KIY74115.1 - 2.4e-56 191.6 2.1 1.2e-31 110.0 0.1 3.0 3 0 0 3 3 3 3 Vps52 / Sac2 family Sec3_C PF09763.9 KIY74115.1 - 6.4e-07 28.2 0.2 3.3e-05 22.5 0.3 2.5 1 1 1 2 2 2 2 Exocyst complex component Sec3 P4Ha_N PF08336.11 KIY74115.1 - 0.045 13.8 0.9 1.4 8.9 0.1 2.4 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Baculo_PEP_C PF04513.12 KIY74115.1 - 0.16 12.0 5.2 0.98 9.5 0.3 2.6 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.12 KIY74115.1 - 0.73 10.3 2.9 4.7 7.8 0.5 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Sugar_tr PF00083.24 KIY74116.1 - 2.7e-124 415.5 11.9 3.1e-124 415.3 11.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY74116.1 - 1e-15 57.6 34.9 1.6e-15 56.9 18.5 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KIY74116.1 - 0.0068 14.9 1.0 0.0092 14.4 1.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) zf-MYND PF01753.18 KIY74117.1 - 3e-07 30.4 11.5 7.6e-07 29.1 11.5 1.8 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KIY74117.1 - 1.9 8.9 10.2 0.14 12.5 5.0 1.9 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding Aldose_epim PF01263.20 KIY74119.1 - 2.6e-57 194.4 0.0 4e-57 193.8 0.0 1.3 1 1 0 1 1 1 1 Aldose 1-epimerase Glyco_hydro_cc PF11790.8 KIY74120.1 - 7.5e-33 114.1 0.0 8.9e-33 113.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Glyco_hydro_cc PF11790.8 KIY74121.1 - 1.4e-41 142.6 0.2 1.6e-41 142.4 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Glyco_hydro_30 PF02055.16 KIY74121.1 - 0.029 13.3 0.0 0.042 12.8 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 30 TIM-barrel domain Sugar_tr PF00083.24 KIY74122.1 - 3.5e-123 411.8 26.7 1.1e-122 410.2 26.7 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY74122.1 - 1.5e-11 43.9 40.7 3e-07 29.7 16.8 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Ifi-6-16 PF06140.13 KIY74123.1 - 8.5e-06 25.6 0.0 1.5e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Interferon-induced 6-16 family ThrE PF06738.12 KIY74124.1 - 1.8e-46 158.5 6.6 1.8e-46 158.5 6.6 2.4 2 1 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 KIY74124.1 - 7.9e-06 26.0 22.9 8e-06 26.0 7.0 2.9 2 1 0 2 2 2 2 Threonine/Serine exporter, ThrE Myb_Cef PF11831.8 KIY74125.1 - 1.4e-56 191.8 0.9 1.4e-56 191.8 0.9 3.9 6 0 0 6 6 6 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 KIY74125.1 - 4.4e-21 74.8 7.1 9.1e-11 41.8 1.3 3.2 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KIY74125.1 - 2.7e-18 66.0 3.5 3e-12 46.6 2.8 3.1 2 1 1 3 3 3 2 Myb-like DNA-binding domain BRCT_2 PF16589.5 KIY74126.1 - 8.7e-09 35.7 0.0 1.5e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 KIY74126.1 - 2e-05 24.8 0.0 4.4e-05 23.7 0.0 1.6 1 1 0 1 1 1 1 DNA ligase 3 BRCT domain BRCT PF00533.26 KIY74126.1 - 0.00024 21.4 0.0 0.00055 20.3 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 KIY74126.1 - 0.00025 20.9 0.0 0.00044 20.1 0.0 1.4 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain SWIRM-assoc_2 PF16496.5 KIY74126.1 - 0.0049 15.8 0.1 0.0049 15.8 0.1 2.1 2 0 0 2 2 2 1 SWIRM-associated domain at the N-terminal Glyco_hydro_cc PF11790.8 KIY74127.1 - 3.8e-37 128.1 0.1 4.5e-37 127.9 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Glyco_hydro_30 PF02055.16 KIY74127.1 - 0.0023 17.0 0.1 0.0038 16.2 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_39 PF01229.17 KIY74127.1 - 0.072 11.7 0.1 0.087 11.4 0.1 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 39 CHCH PF06747.13 KIY74128.1 - 4.9e-06 26.5 8.0 7.1e-06 26.0 8.0 1.3 1 0 0 1 1 1 1 CHCH domain MTCP1 PF08991.10 KIY74128.1 - 0.00014 22.0 5.9 0.0002 21.5 5.9 1.2 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type Pet191_N PF10203.9 KIY74128.1 - 0.00078 19.7 3.9 0.0012 19.1 3.9 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Phage_Cox PF10743.9 KIY74128.1 - 0.037 14.1 0.0 0.046 13.8 0.0 1.1 1 0 0 1 1 1 0 Regulatory phage protein cox UPF0203 PF05254.12 KIY74128.1 - 0.36 11.1 7.8 1.7 8.9 7.8 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) IBR PF01485.21 KIY74129.1 - 5.7e-08 32.9 23.2 1.3e-05 25.3 6.0 4.4 5 0 0 5 5 5 2 IBR domain, a half RING-finger domain zf-C3HC4_2 PF13923.6 KIY74129.1 - 6.3e-07 29.1 2.3 6.3e-07 29.1 2.3 3.6 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KIY74129.1 - 1.3e-06 28.2 1.3 1.3e-06 28.2 1.3 3.5 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.22 KIY74129.1 - 1.3e-06 28.1 0.0 4.3e-06 26.5 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_4 PF15227.6 KIY74129.1 - 5.9e-06 26.3 3.8 5.9e-06 26.3 3.8 4.0 4 0 0 4 4 4 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 KIY74129.1 - 6.1e-06 26.2 5.1 6.1e-06 26.2 5.1 3.7 3 1 0 3 3 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KIY74129.1 - 7.7e-05 22.5 1.9 7.7e-05 22.5 1.9 4.5 4 1 1 5 5 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KIY74129.1 - 0.00099 19.4 3.7 0.00099 19.4 3.7 4.1 3 1 1 4 4 3 1 Ring finger domain zf-RING_5 PF14634.6 KIY74129.1 - 0.0083 16.1 5.2 0.0083 16.1 5.2 4.3 4 2 0 4 4 3 1 zinc-RING finger domain Zn_Tnp_IS91 PF14319.6 KIY74129.1 - 0.014 15.4 0.3 0.014 15.4 0.3 3.3 2 1 1 3 3 3 0 Transposase zinc-binding domain zf-RING_14 PF17978.1 KIY74129.1 - 5.6 7.5 9.0 2 8.9 0.8 2.6 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain SLC35F PF06027.12 KIY74130.1 - 1.6e-95 320.1 16.7 1.9e-95 319.8 16.7 1.0 1 0 0 1 1 1 1 Solute carrier family 35 CRT-like PF08627.10 KIY74130.1 - 5.2e-09 35.5 1.0 5.2e-09 35.5 1.0 1.5 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 KIY74130.1 - 0.26 11.5 23.9 0.11 12.7 5.7 2.7 2 1 1 3 3 3 0 EamA-like transporter family COPI_assoc PF08507.10 KIY74130.1 - 0.92 9.6 8.9 3.4 7.7 1.9 2.5 2 0 0 2 2 2 0 COPI associated protein Pex2_Pex12 PF04757.14 KIY74131.1 - 4.1e-33 114.8 1.7 5.9e-33 114.3 1.7 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_5 PF14634.6 KIY74131.1 - 2.1e-05 24.4 1.8 3.8e-05 23.6 0.2 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KIY74131.1 - 8.8e-05 22.6 1.3 0.00021 21.4 1.3 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 KIY74131.1 - 0.00013 21.9 0.5 0.00037 20.5 0.5 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KIY74131.1 - 0.00024 20.9 0.6 0.00074 19.3 0.6 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KIY74131.1 - 0.0038 17.0 0.1 0.0038 17.0 0.1 2.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KIY74131.1 - 0.012 15.4 3.0 0.038 13.8 1.0 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KIY74131.1 - 0.053 13.4 0.3 0.053 13.4 0.3 1.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KIY74131.1 - 0.091 13.1 4.0 0.11 12.9 0.8 2.2 2 0 0 2 2 2 0 Ring finger domain tRNA-synt_2d PF01409.20 KIY74132.1 - 2e-85 286.2 0.0 4.3e-84 281.8 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 KIY74132.1 - 2e-17 63.2 0.1 2.2e-16 59.9 0.0 2.6 2 0 0 2 2 2 1 PheRS DNA binding domain 3 tRNA_synthFbeta PF17759.1 KIY74132.1 - 1.9e-08 34.0 0.0 8.6e-06 25.3 0.0 2.4 2 0 0 2 2 2 2 Phenylalanyl tRNA synthetase beta chain CLM domain PheRS_DBD2 PF18554.1 KIY74132.1 - 1.4e-06 28.1 0.8 3.4e-06 26.9 0.8 1.7 1 0 0 1 1 1 1 PheRS DNA binding domain 2 tRNA-synt_2b PF00587.25 KIY74132.1 - 0.0021 18.1 0.0 0.0044 17.0 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.20 KIY74132.1 - 0.0028 16.8 0.7 0.023 13.8 0.1 2.4 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) SNase PF00565.17 KIY74133.1 - 2.2e-21 76.4 0.0 3.1e-21 75.9 0.0 1.2 1 0 0 1 1 1 1 Staphylococcal nuclease homologue MFS_1 PF07690.16 KIY74134.1 - 4.4e-43 147.6 30.8 4.4e-43 147.6 30.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KIY74134.1 - 1.7e-09 37.1 4.6 1.7e-09 37.1 4.6 2.7 3 0 0 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 KIY74134.1 - 3 6.0 5.8 2.7 6.2 1.2 2.9 2 1 2 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family CTNNBL PF08216.11 KIY74135.1 - 3.1e-35 120.5 0.0 1.9e-34 117.9 0.0 2.4 2 0 0 2 2 2 1 Catenin-beta-like, Arm-motif containing nuclear Arm PF00514.23 KIY74135.1 - 0.022 14.8 0.1 0.071 13.2 0.1 1.9 1 0 0 1 1 1 0 Armadillo/beta-catenin-like repeat Mo25 PF08569.11 KIY74135.1 - 0.024 14.0 1.4 0.029 13.8 0.4 1.7 2 0 0 2 2 2 0 Mo25-like APH PF01636.23 KIY74136.1 - 4.9e-12 46.3 0.1 7.4e-12 45.7 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KIY74136.1 - 4.1e-06 26.5 0.0 6.8e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase LRR_6 PF13516.6 KIY74137.1 - 0.00046 20.0 5.8 4.2 7.7 0.3 5.4 5 0 0 5 5 5 2 Leucine Rich repeat LRR_4 PF12799.7 KIY74137.1 - 0.0038 17.6 1.5 0.94 10.0 0.0 4.4 4 0 0 4 4 4 1 Leucine Rich repeats (2 copies) XRCC4 PF06632.12 KIY74137.1 - 4 6.2 10.4 18 4.0 9.9 1.9 2 0 0 2 2 2 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 RR_TM4-6 PF06459.12 KIY74137.1 - 4.9 6.9 7.8 8.1 6.2 7.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 WH2 PF02205.20 KIY74138.1 - 3.4e-07 29.9 2.7 4.4e-07 29.5 1.4 1.9 2 0 0 2 2 2 1 WH2 motif SelK_SelG PF10961.8 KIY74138.1 - 3.7 8.2 7.0 7.1 7.3 7.0 1.5 1 0 0 1 1 1 0 Selenoprotein SelK_SelG Thioredoxin PF00085.20 KIY74139.1 - 2.9e-59 197.5 0.1 1.2e-30 105.5 0.0 3.7 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.6 KIY74139.1 - 1.9e-36 125.7 0.0 6.4e-29 101.2 0.0 3.0 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KIY74139.1 - 8.2e-07 29.1 0.1 0.016 15.4 0.0 3.4 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_8 PF13905.6 KIY74139.1 - 1.2e-06 28.8 0.1 0.031 14.6 0.0 3.4 4 1 0 4 4 4 2 Thioredoxin-like AhpC-TSA PF00578.21 KIY74139.1 - 2e-06 27.7 0.3 0.027 14.4 0.0 2.6 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_2 PF13098.6 KIY74139.1 - 2.1e-06 28.1 1.6 0.18 12.3 0.0 3.8 4 1 0 4 4 4 2 Thioredoxin-like domain Calsequestrin PF01216.17 KIY74139.1 - 0.00033 19.8 0.0 0.00084 18.5 0.0 1.6 1 1 1 2 2 2 1 Calsequestrin Redoxin PF08534.10 KIY74139.1 - 0.0009 19.0 1.0 0.82 9.4 0.1 3.1 3 0 0 3 3 3 2 Redoxin OST3_OST6 PF04756.13 KIY74139.1 - 0.016 14.6 0.0 0.57 9.5 0.0 2.4 2 0 0 2 2 2 0 OST3 / OST6 family, transporter family TCTP PF00838.17 KIY74140.1 - 1.1e-72 243.8 0.2 1.2e-72 243.6 0.2 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein UTP15_C PF09384.10 KIY74141.1 - 1.6e-47 160.9 0.0 2.6e-47 160.2 0.0 1.4 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 KIY74141.1 - 7.3e-25 86.8 0.1 1.6e-05 25.5 0.0 6.9 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KIY74141.1 - 4e-12 46.3 0.0 2.2e-05 24.6 0.0 5.0 3 3 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 KIY74141.1 - 0.0068 16.9 0.4 1.6 9.3 0.0 2.9 2 0 0 2 2 2 1 PQQ-like domain PQQ PF01011.21 KIY74141.1 - 0.13 12.2 0.4 0.7 9.9 0.1 2.4 2 0 0 2 2 2 0 PQQ enzyme repeat Frtz PF11768.8 KIY74141.1 - 0.14 10.5 0.0 3.2 6.0 0.0 2.7 3 1 1 4 4 4 0 WD repeat-containing and planar cell polarity effector protein Fritz Med17 PF10156.9 KIY74142.1 - 4e-37 128.0 0.0 4.9e-37 127.7 0.0 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex CDtoxinA PF03498.14 KIY74143.1 - 0.1 12.2 0.3 0.23 11.0 0.3 1.6 1 1 0 1 1 1 0 Cytolethal distending toxin A/C domain Fungal_trans PF04082.18 KIY74144.1 - 1.9e-18 66.5 0.1 3.1e-18 65.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY74144.1 - 5.4e-05 23.2 10.0 9.6e-05 22.4 10.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box-like PF12937.7 KIY74145.1 - 9.5e-06 25.4 0.3 6.7e-05 22.7 0.0 2.6 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KIY74145.1 - 0.013 15.3 0.1 0.085 12.8 0.0 2.4 2 0 0 2 2 2 0 F-box domain NmrA PF05368.13 KIY74146.1 - 3e-18 66.2 0.0 3.9e-18 65.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KIY74146.1 - 3.5e-08 33.6 0.0 1.2e-07 31.8 0.0 1.8 1 1 0 1 1 1 1 NAD(P)H-binding THF_DHG_CYH_C PF02882.19 KIY74146.1 - 0.065 12.5 0.0 0.18 11.2 0.0 1.6 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Sacchrp_dh_NADP PF03435.18 KIY74146.1 - 0.069 13.4 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DUF166 PF02593.14 KIY74146.1 - 0.13 11.7 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function Epimerase PF01370.21 KIY74146.1 - 0.13 11.6 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Ribosomal_L22e PF01776.17 KIY74147.1 - 1.7e-47 160.3 0.4 2.1e-47 160.0 0.4 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family AdoMet_Synthase PF01941.19 KIY74147.1 - 0.032 13.0 0.0 0.035 12.9 0.0 1.0 1 0 0 1 1 1 0 S-adenosylmethionine synthetase (AdoMet synthetase) NmrA PF05368.13 KIY74148.1 - 5.9e-24 84.9 0.0 7.1e-24 84.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KIY74148.1 - 5.3e-10 39.5 0.0 1e-09 38.5 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KIY74148.1 - 8.7e-07 28.2 0.1 1.4e-06 27.5 0.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KIY74148.1 - 1e-05 25.2 0.0 1.5e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 KIY74148.1 - 1.1e-05 25.5 0.2 0.00016 21.8 0.0 2.4 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_4 PF07993.12 KIY74148.1 - 0.00027 20.2 0.0 0.00039 19.7 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 KIY74148.1 - 0.0027 17.2 0.0 0.004 16.6 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Semialdhyde_dh PF01118.24 KIY74148.1 - 0.0045 17.4 0.1 0.013 15.9 0.1 1.9 2 1 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KIY74148.1 - 0.0048 17.1 0.1 0.0083 16.4 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 KIY74148.1 - 0.0059 15.8 0.0 0.0092 15.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DapB_N PF01113.20 KIY74148.1 - 0.014 15.5 0.2 0.031 14.4 0.1 1.6 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus KR PF08659.10 KIY74148.1 - 0.018 15.0 0.0 0.027 14.4 0.0 1.3 1 0 0 1 1 1 0 KR domain adh_short PF00106.25 KIY74148.1 - 0.072 12.5 0.1 0.12 11.8 0.1 1.4 1 1 0 1 1 1 0 short chain dehydrogenase DUF1353 PF07087.11 KIY74148.1 - 0.14 11.9 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1353) Transp_cyt_pur PF02133.15 KIY74149.1 - 2.2e-113 379.4 30.7 2.5e-113 379.2 30.7 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin CTV_P6 PF06706.11 KIY74149.1 - 0.14 11.9 2.3 0.6 9.9 0.1 2.8 2 0 0 2 2 2 0 Citrus tristeza virus 6-kDa protein DUF2374 PF09574.10 KIY74149.1 - 1.5 8.7 0.0 1.5 8.7 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (Duf2374) CRCB PF02537.15 KIY74150.1 - 9.2e-31 106.0 17.3 5.6e-19 68.2 6.1 2.3 2 0 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) adh_short PF00106.25 KIY74151.1 - 4.4e-24 85.0 0.0 5.8e-24 84.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KIY74151.1 - 8.6e-12 45.1 0.0 1.1e-11 44.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KIY74151.1 - 2.3e-06 27.6 0.0 4.1e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_7 PF13241.6 KIY74151.1 - 0.0093 16.4 0.0 0.018 15.5 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding TRAP_alpha PF03896.16 KIY74151.1 - 0.024 13.8 0.0 0.039 13.1 0.0 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit THF_DHG_CYH_C PF02882.19 KIY74151.1 - 0.049 13.0 0.0 0.076 12.3 0.0 1.2 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain TspO_MBR PF03073.15 KIY74152.1 - 1.8e-36 125.2 13.1 2.1e-36 125.0 13.1 1.0 1 0 0 1 1 1 1 TspO/MBR family SNARE_assoc PF09335.11 KIY74153.1 - 7.1e-20 71.7 2.3 7.1e-20 71.7 2.3 1.7 2 0 0 2 2 2 1 SNARE associated Golgi protein zf-C2H2 PF00096.26 KIY74155.1 - 1.5e-07 31.5 17.9 0.00049 20.4 1.4 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIY74155.1 - 2.8e-06 27.7 17.0 0.018 15.8 1.5 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KIY74155.1 - 0.022 15.0 0.6 0.97 9.8 0.6 2.7 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 KIY74155.1 - 0.072 13.4 1.6 0.09 13.1 0.1 1.9 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Zn-C2H2_12 PF18112.1 KIY74155.1 - 0.22 12.0 0.5 0.22 12.0 0.5 2.3 2 1 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_11 PF16622.5 KIY74155.1 - 1.6 8.5 9.0 0.27 11.0 1.1 3.2 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-H2C2_2 PF13465.6 KIY74155.1 - 7.9 7.1 15.2 8.1 7.1 1.2 4.1 3 1 1 4 4 4 0 Zinc-finger double domain DUF89 PF01937.19 KIY74156.1 - 1.3e-110 369.7 0.0 1.5e-110 369.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 WWE PF02825.20 KIY74156.1 - 0.11 13.1 0.0 0.25 11.9 0.0 1.6 1 0 0 1 1 1 0 WWE domain RhoGEF PF00621.20 KIY74157.1 - 1.2e-36 126.7 0.0 2.1e-36 125.9 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain Mito_carr PF00153.27 KIY74158.1 - 1.5e-62 207.6 4.4 1.7e-22 79.1 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 KIY74158.1 - 6e-06 26.6 0.2 2.9e-05 24.4 0.1 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KIY74158.1 - 0.00012 21.7 1.0 0.002 17.9 0.2 3.2 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 KIY74158.1 - 0.00075 18.9 1.3 0.0098 15.4 0.2 3.0 3 0 0 3 3 3 1 EF hand EF-hand_5 PF13202.6 KIY74158.1 - 0.095 12.2 1.8 0.15 11.6 0.5 2.0 2 0 0 2 2 2 0 EF hand CYSTM PF12734.7 KIY74159.1 - 0.064 13.6 1.2 1.9 8.9 0.0 2.8 3 0 0 3 3 3 0 Cysteine-rich TM module stress tolerance CASP_C PF08172.12 KIY74159.1 - 0.2 11.0 0.5 0.29 10.4 0.5 1.2 1 0 0 1 1 1 0 CASP C terminal MBOAT PF03062.19 KIY74160.1 - 4e-39 135.0 14.5 4e-39 135.0 14.5 2.1 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family CK_II_beta PF01214.18 KIY74161.1 - 3.4e-74 248.6 0.0 4.4e-74 248.2 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit BUD22 PF09073.10 KIY74161.1 - 0.98 8.7 6.3 0.11 11.8 2.0 1.6 2 0 0 2 2 2 0 BUD22 Ribosomal_L36e PF01158.18 KIY74162.1 - 6.1e-30 103.3 0.7 2.1e-28 98.4 0.7 2.0 1 1 0 1 1 1 1 Ribosomal protein L36e TPP_enzyme_N PF02776.18 KIY74163.1 - 6.6e-35 120.3 0.1 9.7e-35 119.7 0.1 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 KIY74163.1 - 2.1e-16 59.9 0.0 7.4e-16 58.1 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 KIY74163.1 - 6.5e-14 52.0 0.0 1.8e-12 47.3 0.0 2.5 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DUF3882 PF07066.11 KIY74163.1 - 0.082 13.0 0.0 0.97 9.5 0.0 2.2 2 0 0 2 2 2 0 Lactococcus phage M3 protein IBN_N PF03810.19 KIY74164.1 - 3e-08 33.5 0.0 3.6e-05 23.6 0.0 2.9 2 0 0 2 2 2 2 Importin-beta N-terminal domain Slx4 PF09494.10 KIY74165.1 - 0.0012 18.8 0.0 0.003 17.5 0.0 1.7 1 0 0 1 1 1 1 Slx4 endonuclease Mur_ligase_M PF08245.12 KIY74166.1 - 3.3e-07 30.5 0.0 0.0001 22.4 0.0 2.9 1 1 1 2 2 2 2 Mur ligase middle domain PALP PF00291.25 KIY74167.1 - 1.8e-66 224.6 0.2 2e-66 224.4 0.2 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme AMP-binding PF00501.28 KIY74168.1 - 4.8e-72 242.9 0.0 6.1e-72 242.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KIY74168.1 - 6e-10 40.0 0.0 1.6e-09 38.6 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Phosducin PF02114.16 KIY74169.1 - 3.1e-06 26.4 0.1 4e-06 26.0 0.1 1.1 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.20 KIY74169.1 - 0.042 13.8 0.1 0.067 13.2 0.1 1.3 1 0 0 1 1 1 0 Thioredoxin eRF1_1 PF03463.15 KIY74170.1 - 2.8e-47 159.9 0.0 5.5e-47 159.0 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.15 KIY74170.1 - 4e-23 82.0 0.0 1e-22 80.7 0.0 1.8 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_2 PF03464.15 KIY74170.1 - 6.6e-21 75.0 0.1 1.1e-20 74.3 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 2 Glyco_trans_4_2 PF13477.6 KIY74170.1 - 0.01 15.8 0.2 5.9 6.9 0.0 2.5 2 1 0 2 2 2 0 Glycosyl transferase 4-like ETF PF01012.21 KIY74170.1 - 0.11 12.4 2.0 0.11 12.4 0.2 1.9 2 0 0 2 2 2 0 Electron transfer flavoprotein domain CHASE2 PF05226.11 KIY74170.1 - 0.12 12.1 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 CHASE2 domain COR PF16095.5 KIY74170.1 - 0.13 12.0 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 C-terminal of Roc, COR, domain FAD_binding_7 PF03441.14 KIY74171.1 - 3e-74 248.9 0.3 5.4e-74 248.1 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 KIY74171.1 - 1.4e-37 129.2 0.1 2.4e-37 128.5 0.1 1.4 1 0 0 1 1 1 1 DNA photolyase Usp PF00582.26 KIY74171.1 - 0.028 14.9 0.2 0.078 13.5 0.0 1.8 2 0 0 2 2 2 0 Universal stress protein family LSM PF01423.22 KIY74172.1 - 1.2e-17 63.3 0.0 1.6e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KIY74172.1 - 0.075 13.2 0.0 0.094 12.9 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain Feld-I_B PF09252.10 KIY74172.1 - 0.14 12.2 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 Allergen Fel d I-B chain BTB PF00651.31 KIY74174.1 - 0.033 14.4 0.0 0.11 12.7 0.0 1.8 1 1 0 1 1 1 0 BTB/POZ domain Cyt-b5 PF00173.28 KIY74175.1 - 6.3e-19 67.9 0.0 8.4e-19 67.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain MBOAT_2 PF13813.6 KIY74176.1 - 3.1e-12 46.6 0.7 3.1e-12 46.6 0.7 2.5 3 0 0 3 3 3 1 Membrane bound O-acyl transferase family FTA4 PF13093.6 KIY74177.1 - 0.25 11.2 3.9 0.39 10.6 3.7 1.6 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 FAD_binding_3 PF01494.19 KIY74178.1 - 8.5e-68 229.1 0.0 1.1e-67 228.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KIY74178.1 - 0.00036 19.9 0.0 0.076 12.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KIY74178.1 - 0.011 14.4 0.1 0.017 13.8 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_2 PF00890.24 KIY74178.1 - 0.029 13.5 0.1 0.048 12.7 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_8 PF13450.6 KIY74178.1 - 0.043 14.0 0.1 0.27 11.5 0.0 2.5 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KIY74178.1 - 0.058 12.7 0.1 0.087 12.1 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pkinase PF00069.25 KIY74179.1 - 6.9e-35 120.7 0.0 4.2e-34 118.1 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY74179.1 - 8.3e-11 41.6 0.0 6.8e-10 38.7 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KIY74179.1 - 0.0018 18.2 0.1 0.0035 17.3 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KIY74179.1 - 0.13 11.6 0.0 4.5 6.5 0.0 2.1 2 0 0 2 2 2 0 Kinase-like PAF-AH_p_II PF03403.13 KIY74180.1 - 4.7e-37 127.4 0.0 3.9e-34 117.8 0.0 2.0 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 KIY74180.1 - 2.9e-05 23.1 0.0 0.0069 15.3 0.0 2.3 2 0 0 2 2 2 2 Chlorophyllase enzyme Hydrolase_4 PF12146.8 KIY74180.1 - 0.0001 21.7 0.0 0.1 11.8 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 KIY74180.1 - 0.0029 16.7 0.0 0.4 9.7 0.0 2.2 2 0 0 2 2 2 2 Chlorophyllase Thioesterase PF00975.20 KIY74180.1 - 0.0059 16.7 1.6 2 8.4 0.9 3.0 2 1 1 3 3 3 2 Thioesterase domain Abhydrolase_6 PF12697.7 KIY74180.1 - 0.0071 17.0 0.2 0.023 15.3 0.1 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF87 PF01935.17 KIY74182.1 - 0.00029 21.0 0.0 0.014 15.5 0.0 2.2 2 0 0 2 2 2 1 Helicase HerA, central domain Zot PF05707.12 KIY74182.1 - 0.0034 17.0 0.0 0.014 15.0 0.0 1.9 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_22 PF13401.6 KIY74182.1 - 0.013 15.7 0.0 4.2 7.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 KIY74182.1 - 0.028 13.8 0.1 0.056 12.8 0.1 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_16 PF13191.6 KIY74182.1 - 0.079 13.3 0.0 8.1 6.8 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA PF00004.29 KIY74182.1 - 0.092 13.2 0.1 0.87 10.0 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 KIY74183.1 - 2.9e-21 76.3 0.0 9.4e-21 74.6 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) SpoOE-like PF09388.10 KIY74183.1 - 0.029 14.3 0.7 0.089 12.7 0.1 2.0 2 0 0 2 2 2 0 Spo0E like sporulation regulatory protein AAA_22 PF13401.6 KIY74183.1 - 0.077 13.3 0.1 1.5 9.1 0.0 2.4 1 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KIY74183.1 - 0.079 13.3 0.0 0.42 11.0 0.0 2.1 1 1 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.6 KIY74183.1 - 0.12 12.8 0.0 0.2 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KIY74183.1 - 0.12 12.2 0.0 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain DPBB_1 PF03330.18 KIY74184.1 - 3.7e-05 23.9 1.4 6.4e-05 23.2 0.1 2.1 2 1 0 2 2 2 1 Lytic transglycolase CBM_5_12 PF02839.14 KIY74184.1 - 0.00052 20.4 8.2 0.0018 18.8 3.4 3.1 2 1 0 2 2 2 1 Carbohydrate binding domain P16-Arc PF04699.14 KIY74185.1 - 3.1e-50 170.5 0.0 3.5e-50 170.4 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Utp12 PF04003.12 KIY74185.1 - 0.0023 18.2 0.0 0.0041 17.4 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family WD40 PF00400.32 KIY74186.1 - 5.2e-08 33.4 6.9 0.001 19.8 0.4 4.8 5 0 0 5 5 5 2 WD domain, G-beta repeat F-box-like PF12937.7 KIY74186.1 - 0.00022 21.1 1.1 0.00032 20.5 0.2 1.7 2 0 0 2 2 2 1 F-box-like F-box_4 PF15966.5 KIY74186.1 - 0.0041 17.0 0.0 0.012 15.4 0.0 1.8 1 0 0 1 1 1 1 F-box F-box PF00646.33 KIY74186.1 - 0.0071 16.2 0.0 0.017 15.0 0.0 1.6 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 KIY74186.1 - 0.034 14.4 0.0 6.7 7.1 0.0 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain UIM PF02809.20 KIY74186.1 - 0.049 13.6 9.7 0.055 13.4 3.5 2.7 2 0 0 2 2 2 0 Ubiquitin interaction motif BBS2_Mid PF14783.6 KIY74186.1 - 0.094 12.8 0.0 3.7 7.6 0.0 2.9 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region SANT_DAMP1_like PF16282.5 KIY74187.1 - 1.9e-27 95.3 5.2 3.3e-27 94.5 5.2 1.4 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_6 PF13921.6 KIY74187.1 - 0.0018 18.5 0.3 0.0052 17.0 0.3 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KIY74187.1 - 0.013 15.7 0.0 0.013 15.7 0.0 2.0 2 0 0 2 2 2 0 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 KIY74187.1 - 0.015 15.3 0.1 0.1 12.7 0.0 2.4 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain DUF202 PF02656.15 KIY74188.1 - 4.9e-15 55.7 4.7 5.5e-15 55.6 2.5 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) p450 PF00067.22 KIY74189.1 - 1.2e-62 212.2 0.0 2.3e-62 211.3 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 ECH_1 PF00378.20 KIY74190.1 - 8.1e-33 113.8 0.0 1.4e-32 113.0 0.0 1.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KIY74190.1 - 1.3e-19 70.9 0.0 1.6e-17 64.0 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase DUF4470 PF14737.6 KIY74191.1 - 1.1e-23 83.3 0.1 2.2e-23 82.3 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) DUF1967 PF09269.11 KIY74191.1 - 0.032 14.2 0.0 7.5 6.6 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1967) F-box-like PF12937.7 KIY74192.1 - 2e-10 40.4 4.1 4.5e-10 39.3 4.1 1.7 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KIY74192.1 - 5.4e-09 36.2 7.5 0.35 11.3 0.0 7.2 8 1 1 10 10 10 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KIY74192.1 - 2.5e-06 27.1 9.5 5.1 7.4 0.0 9.9 11 0 0 11 11 11 1 Leucine Rich repeat DNA_pol_phi PF04931.13 KIY74192.1 - 2.8 6.0 5.1 5.4 5.0 5.1 1.4 1 0 0 1 1 1 0 DNA polymerase phi LSM PF01423.22 KIY74194.1 - 1.3e-18 66.4 0.0 1.5e-18 66.3 0.0 1.1 1 0 0 1 1 1 1 LSM domain zf-U1 PF06220.12 KIY74195.1 - 1.4e-20 72.8 4.4 1.9e-20 72.3 4.4 1.2 1 0 0 1 1 1 1 U1 zinc finger CLIP1_ZNF PF16641.5 KIY74195.1 - 0.16 11.9 2.3 0.25 11.3 2.3 1.3 1 0 0 1 1 1 0 CLIP1 zinc knuckle Amidohydro_2 PF04909.14 KIY74196.1 - 1.2e-26 94.2 0.0 4.6e-26 92.3 0.0 1.8 1 1 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.21 KIY74196.1 - 0.02 14.3 0.0 0.046 13.1 0.0 1.6 1 0 0 1 1 1 0 TatD related DNase Epimerase PF01370.21 KIY74197.1 - 5.3e-15 55.5 0.0 6.9e-15 55.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KIY74197.1 - 7.8e-13 48.1 0.0 1.1e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KIY74197.1 - 3e-09 37.0 0.1 5.1e-09 36.3 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KIY74197.1 - 5.6e-08 32.3 0.0 1.5e-06 27.6 0.0 2.2 2 0 0 2 2 2 1 Male sterility protein NmrA PF05368.13 KIY74197.1 - 2.1e-05 24.2 0.3 3.1e-05 23.6 0.3 1.3 1 0 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 KIY74197.1 - 3.2e-05 23.5 0.0 4.3e-05 23.1 0.0 1.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 KIY74197.1 - 0.00073 19.0 0.3 0.0057 16.1 0.3 2.1 1 1 0 1 1 1 1 short chain dehydrogenase Cons_hypoth95 PF03602.15 KIY74197.1 - 0.0086 15.7 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Lactamase_B_6 PF16661.5 KIY74198.1 - 2.1e-51 174.1 0.0 7.9e-50 169.0 0.0 2.6 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily domain Beta-Casp PF10996.8 KIY74198.1 - 5.3e-21 75.0 0.0 4.4e-20 72.0 0.0 2.3 2 0 0 2 2 2 1 Beta-Casp domain CPSF100_C PF13299.6 KIY74198.1 - 2.7e-19 70.0 10.8 7.3e-19 68.6 0.1 3.8 3 1 0 3 3 3 1 Cleavage and polyadenylation factor 2 C-terminal RMMBL PF07521.12 KIY74198.1 - 1.9e-07 30.9 0.0 4.1e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 KIY74198.1 - 0.0025 17.4 0.1 0.12 11.9 0.1 2.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain DUF4454 PF14628.6 KIY74198.1 - 0.031 14.1 0.0 0.063 13.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4454) UBN_AB PF14075.6 KIY74198.1 - 2.3 7.9 7.0 11 5.7 2.0 2.8 3 0 0 3 3 3 0 Ubinuclein conserved middle domain Peptidase_C42 PF05533.12 KIY74200.1 - 0.047 13.7 0.0 0.076 13.1 0.0 1.2 1 0 0 1 1 1 0 Beet yellows virus-type papain-like endopeptidase C42 Flavin_Reduct PF01613.18 KIY74200.1 - 0.1 12.7 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Flavin reductase like domain Abhydrolase_3 PF07859.13 KIY74201.1 - 7e-38 130.6 0.0 1.4e-29 103.5 0.0 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KIY74201.1 - 5.4e-07 28.8 0.0 1.5e-06 27.3 0.0 1.7 2 0 0 2 2 2 1 Steryl acetyl hydrolase COesterase PF00135.28 KIY74201.1 - 0.03 13.2 0.0 0.056 12.3 0.0 1.4 1 0 0 1 1 1 0 Carboxylesterase family tRNA-synt_1c PF00749.21 KIY74202.1 - 1.2e-107 359.5 0.0 1.7e-107 359.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA_synt_1c_R1 PF04558.15 KIY74202.1 - 3.3e-37 128.0 0.0 6.3e-37 127.1 0.0 1.4 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA-synt_1c_C PF03950.18 KIY74202.1 - 1.1e-32 113.3 0.0 2.1e-32 112.4 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R2 PF04557.15 KIY74202.1 - 9.2e-06 26.5 0.8 9.2e-06 26.5 0.8 2.1 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 TMEM154 PF15102.6 KIY74205.1 - 6.5 6.7 0.0 6.5 6.7 0.0 5.4 2 1 3 5 5 5 0 TMEM154 protein family ECH_1 PF00378.20 KIY74206.1 - 1.3e-51 175.3 0.0 1.5e-51 175.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KIY74206.1 - 2.3e-31 109.6 0.2 4e-29 102.2 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase CLP_protease PF00574.23 KIY74206.1 - 0.1 12.5 0.1 12 5.7 0.0 2.3 1 1 1 2 2 2 0 Clp protease Tim54 PF11711.8 KIY74207.1 - 1.3e-56 192.0 0.8 1.1e-46 159.3 0.3 2.2 1 1 1 2 2 2 2 Inner membrane protein import complex subunit Tim54 zf-H2C2_2 PF13465.6 KIY74208.1 - 6.6e-20 70.6 57.1 4.3e-06 26.9 0.4 9.2 11 0 0 11 11 11 6 Zinc-finger double domain zf-C2H2 PF00096.26 KIY74208.1 - 4.3e-09 36.3 52.3 0.5 10.9 0.1 9.3 9 0 0 9 9 9 6 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 KIY74208.1 - 0.0057 16.4 0.2 0.0057 16.4 0.2 8.3 10 0 0 10 10 10 5 C2H2-type zinc-finger domain DUF5579 PF17742.1 KIY74208.1 - 0.016 14.7 1.6 4.4 6.8 0.0 3.0 2 1 1 3 3 3 0 Family of unknown function (DUF5579) zf-C2H2_4 PF13894.6 KIY74208.1 - 0.02 15.7 48.3 5 8.2 1.6 9.2 9 0 0 9 9 9 0 C2H2-type zinc finger OrsD PF12013.8 KIY74208.1 - 0.12 12.8 22.9 16 6.0 0.2 6.6 5 2 1 6 6 6 0 Orsellinic acid/F9775 biosynthesis cluster protein D SURF2 PF05477.11 KIY74208.1 - 0.6 9.8 11.0 0.96 9.1 11.0 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) zf-C2H2_8 PF15909.5 KIY74208.1 - 0.94 9.8 23.0 0.44 10.9 3.5 4.0 2 1 2 4 4 4 0 C2H2-type zinc ribbon Sugar_tr PF00083.24 KIY74209.1 - 7.4e-103 344.8 17.1 9.4e-103 344.5 17.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KIY74209.1 - 2.3e-19 69.5 43.1 2.7e-16 59.4 20.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KIY74209.1 - 0.16 10.3 14.2 0.037 12.3 1.2 3.2 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family OTCace PF00185.24 KIY74210.1 - 1.2e-45 155.4 0.0 1.7e-45 154.9 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 KIY74210.1 - 1.4e-43 148.4 0.0 2.2e-43 147.8 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OCD_Mu_crystall PF02423.15 KIY74210.1 - 0.071 12.0 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family Tubulin PF00091.25 KIY74211.1 - 3.2e-66 223.3 0.0 4.3e-66 222.9 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KIY74211.1 - 5.2e-47 159.1 0.0 8.2e-47 158.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KIY74211.1 - 0.0009 19.0 0.0 0.0018 18.0 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Lipase_3 PF01764.25 KIY74211.1 - 0.01 15.7 0.0 2.3 8.1 0.0 2.3 2 0 0 2 2 2 0 Lipase (class 3) Tubulin PF00091.25 KIY74212.1 - 5.4e-65 219.3 0.0 7.1e-65 218.9 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KIY74212.1 - 3.8e-48 162.8 0.0 5.7e-48 162.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Lipase_3 PF01764.25 KIY74212.1 - 0.029 14.2 0.0 2.6 7.9 0.0 2.2 2 0 0 2 2 2 0 Lipase (class 3) Tubulin_3 PF14881.6 KIY74212.1 - 0.03 14.0 0.0 0.055 13.2 0.0 1.4 1 0 0 1 1 1 0 Tubulin domain Tubulin_2 PF13809.6 KIY74212.1 - 0.22 10.7 0.0 0.33 10.1 0.0 1.2 1 0 0 1 1 1 0 Tubulin like Epimerase PF01370.21 KIY74213.1 - 3.6e-18 65.9 0.0 5.1e-18 65.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KIY74213.1 - 1.1e-12 47.6 0.0 1.4e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KIY74213.1 - 1.9e-10 40.9 0.0 3e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KIY74213.1 - 1.9e-10 40.7 0.0 6.5e-10 38.9 0.0 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KIY74213.1 - 4.3e-08 32.6 0.0 5.3e-07 29.1 0.0 2.2 2 1 0 2 2 2 1 Male sterility protein NmrA PF05368.13 KIY74213.1 - 1.5e-06 28.0 0.0 2.9e-06 27.0 0.1 1.5 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.25 KIY74213.1 - 0.00045 19.7 0.3 0.0041 16.6 0.3 2.1 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 KIY74213.1 - 0.0021 17.3 0.0 0.0033 16.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short_C2 PF13561.6 KIY74213.1 - 0.15 11.6 0.2 1.2 8.6 0.2 2.1 1 1 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase QRPTase_C PF01729.19 KIY74214.1 - 6.8e-48 162.6 0.1 8.4e-48 162.3 0.1 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 KIY74214.1 - 1.8e-19 69.6 0.2 5.1e-19 68.1 0.1 1.8 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain Arf PF00025.21 KIY74215.1 - 5.5e-79 263.7 0.1 6.3e-79 263.5 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KIY74215.1 - 8.2e-15 55.1 0.0 1.1e-14 54.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KIY74215.1 - 3.6e-14 52.6 0.0 4.5e-14 52.3 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 KIY74215.1 - 2.3e-13 50.1 0.0 2.5e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 KIY74215.1 - 5e-12 45.7 0.9 4.1e-08 32.8 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 KIY74215.1 - 2.8e-10 39.9 0.0 3.5e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KIY74215.1 - 2.9e-06 27.3 0.0 4.4e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 KIY74215.1 - 0.01 15.2 0.2 0.015 14.6 0.2 1.5 1 1 0 1 1 1 0 6-phosphofructo-2-kinase DSPc PF00782.20 KIY74216.1 - 3.7e-28 98.0 0.0 4.3e-28 97.8 0.0 1.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KIY74216.1 - 0.003 17.2 0.1 0.0034 17.0 0.1 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 KIY74216.1 - 0.0034 17.7 0.0 0.0063 16.8 0.0 1.4 2 0 0 2 2 2 1 Rit1 DUSP-like domain DUF442 PF04273.13 KIY74216.1 - 0.14 12.2 0.0 0.38 10.8 0.0 1.7 1 1 1 2 2 2 0 Putative phosphatase (DUF442) DUF2076 PF09849.9 KIY74217.1 - 0.00078 19.6 17.8 0.0011 19.0 17.7 1.3 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) DUF3245 PF11595.8 KIY74218.1 - 7.7e-05 23.2 0.3 7.7e-05 23.2 0.3 3.7 2 2 2 4 4 4 2 Protein of unknown function (DUF3245) PGA2 PF07543.12 KIY74218.1 - 0.58 10.1 9.7 0.062 13.3 2.4 2.1 2 0 0 2 2 2 0 Protein trafficking PGA2 SIP1 PF04938.12 KIY74219.1 - 4.9e-23 82.0 0.0 6.2e-23 81.7 0.0 1.1 1 0 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) GPI-anchored PF10342.9 KIY74220.1 - 8.8e-10 39.2 2.0 9.6e-10 39.1 0.0 2.0 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF2606 PF10794.9 KIY74220.1 - 0.18 11.6 0.0 0.3 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2606) Period_C PF12114.8 KIY74220.1 - 7.3 6.1 12.7 11 5.5 12.7 1.3 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Sec15 PF04091.12 KIY74221.1 - 1.7e-91 306.9 0.1 3e-91 306.1 0.1 1.3 1 0 0 1 1 1 1 Exocyst complex subunit Sec15-like COG5 PF10392.9 KIY74221.1 - 8.2e-08 32.5 1.7 6.8e-07 29.5 0.0 2.8 2 0 0 2 2 2 1 Golgi transport complex subunit 5 Vps51 PF08700.11 KIY74221.1 - 1.1e-05 25.4 0.3 0.00011 22.2 0.2 2.7 1 1 1 2 2 2 1 Vps51/Vps67 Prominin PF05478.11 KIY74221.1 - 0.0024 15.9 0.7 0.02 12.9 0.2 2.1 2 0 0 2 2 2 1 Prominin Zw10 PF06248.13 KIY74221.1 - 0.003 16.2 0.6 0.012 14.2 0.0 2.2 2 0 0 2 2 2 1 Centromere/kinetochore Zw10 Dor1 PF04124.12 KIY74221.1 - 0.0095 14.7 1.2 1.4 7.5 0.1 2.4 2 0 0 2 2 2 2 Dor1-like family Sec8_exocyst PF04048.14 KIY74221.1 - 0.034 14.0 0.9 0.096 12.6 0.1 2.2 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain COG2 PF06148.11 KIY74221.1 - 0.04 14.0 5.8 0.098 12.7 0.5 3.3 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 HAD_2 PF13419.6 KIY74222.1 - 4.5e-18 66.0 0.0 8.6e-18 65.0 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KIY74222.1 - 9.3e-13 48.9 0.1 6.6e-11 42.9 0.1 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KIY74222.1 - 9e-06 25.7 0.0 1.8e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 KIY74222.1 - 0.016 15.6 0.0 0.02 15.3 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 KIY74222.1 - 0.12 12.5 0.0 0.42 10.7 0.0 1.9 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KIY74223.1 - 3.6e-18 66.3 0.0 5.1e-18 65.8 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KIY74223.1 - 2.1e-12 47.8 0.1 1e-10 42.3 0.1 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KIY74223.1 - 6.9e-07 29.2 0.1 1.9e-05 24.7 0.0 2.6 2 1 1 3 3 3 1 HAD-hyrolase-like HAD PF12710.7 KIY74223.1 - 0.0034 17.8 0.0 0.005 17.3 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 KIY74223.1 - 0.0035 17.4 0.0 0.24 11.5 0.0 2.5 3 0 0 3 3 3 1 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KIY74223.1 - 0.2 11.3 0.0 0.29 10.8 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase PALP PF00291.25 KIY74224.1 - 8.4e-43 146.9 0.1 9.5e-43 146.7 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme HAD_2 PF13419.6 KIY74225.1 - 6.4e-07 29.6 0.0 2.1e-06 27.9 0.0 1.8 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KIY74225.1 - 0.0013 19.0 0.0 0.0026 18.1 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase ADH_zinc_N PF00107.26 KIY74225.1 - 0.044 13.8 0.2 0.13 12.2 0.1 1.8 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Sec10 PF07393.11 KIY74226.1 - 4.7e-222 739.3 0.0 6.1e-222 739.0 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 COG2 PF06148.11 KIY74226.1 - 0.017 15.2 0.7 0.16 12.1 0.2 2.8 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Peptidase_S46 PF10459.9 KIY74226.1 - 0.024 13.3 1.5 0.052 12.2 1.5 1.5 1 0 0 1 1 1 0 Peptidase S46 I_LWEQ PF01608.17 KIY74226.1 - 0.039 14.2 0.1 0.15 12.3 0.1 2.0 1 0 0 1 1 1 0 I/LWEQ domain BAR_3_WASP_bdg PF10456.9 KIY74226.1 - 0.039 13.4 0.5 0.1 12.1 0.2 1.9 2 0 0 2 2 2 0 WASP-binding domain of Sorting nexin protein Baculo_PEP_C PF04513.12 KIY74226.1 - 0.04 14.0 0.0 0.12 12.4 0.0 1.8 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 KIY74226.1 - 0.055 13.5 1.4 0.15 12.1 1.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) GNAT_like PF18407.1 KIY74226.1 - 0.12 12.7 0.3 0.33 11.3 0.3 1.7 1 0 0 1 1 1 0 GCN5-related N-acetyltransferase like domain NuA4 PF09340.10 KIY74226.1 - 0.13 12.2 0.2 0.37 10.7 0.2 1.8 1 0 0 1 1 1 0 Histone acetyltransferase subunit NuA4 DUF4038 PF13204.6 KIY74227.1 - 2.3e-93 313.2 0.2 3.1e-93 312.8 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4038) Collagen_bind_2 PF12904.7 KIY74227.1 - 7.5e-10 38.7 0.0 1.4e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Putative collagen-binding domain of a collagenase Ribosomal_S6e PF01092.19 KIY74228.1 - 6.6e-54 181.2 0.0 1.1e-53 180.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S6e Ribosomal_S13_N PF08069.12 KIY74229.1 - 1.9e-30 104.7 0.1 3.7e-30 103.8 0.1 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 KIY74229.1 - 9.4e-15 54.6 0.1 1.4e-14 54.1 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 YflT PF11181.8 KIY74229.1 - 0.11 13.0 0.0 0.2 12.2 0.0 1.5 2 0 0 2 2 2 0 Heat induced stress protein YflT Rho_N PF07498.12 KIY74230.1 - 3.2e-05 23.8 0.4 6e-05 22.9 0.4 1.4 1 0 0 1 1 1 1 Rho termination factor, N-terminal domain HeH PF12949.7 KIY74230.1 - 0.0003 20.4 0.2 0.0003 20.4 0.2 2.1 2 0 0 2 2 2 1 HeH/LEM domain Gp138_N PF18352.1 KIY74230.1 - 0.11 12.5 0.1 0.86 9.7 0.0 2.3 2 1 1 3 3 3 0 Phage protein Gp138 N-terminal domain CCT_2 PF09425.10 KIY74230.1 - 0.2 11.6 0.1 0.2 11.6 0.1 1.9 2 0 0 2 2 2 0 Divergent CCT motif DUF3235 PF11574.8 KIY74230.1 - 0.82 10.6 7.2 1.8 9.5 6.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3235) Virul_Fac PF10139.9 KIY74230.1 - 0.92 7.7 3.3 1.1 7.3 3.3 1.0 1 0 0 1 1 1 0 Putative bacterial virulence factor CBFB_NFYA PF02045.15 KIY74231.1 - 2.1e-28 98.7 8.1 2.5e-28 98.5 8.1 1.1 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Ribosomal_S13 PF00416.22 KIY74232.1 - 4.6e-55 185.5 1.8 5.4e-55 185.2 1.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 DUF2746 PF10874.8 KIY74232.1 - 0.011 16.1 0.0 0.02 15.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2746) FbpA PF05833.11 KIY74232.1 - 0.011 14.5 0.0 0.014 14.2 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) HHH_6 PF14579.6 KIY74232.1 - 0.034 14.4 0.1 0.12 12.7 0.1 1.9 1 1 0 1 1 1 0 Helix-hairpin-helix motif Spt20 PF12090.8 KIY74234.1 - 3.7e-25 88.9 0.0 1.6e-15 57.3 0.0 6.9 3 3 2 5 5 5 2 Spt20 family DUF4810 PF16068.5 KIY74234.1 - 0.025 15.1 7.4 0.025 15.1 7.4 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4810) DUF383 PF04063.14 KIY74235.1 - 1.4e-57 194.5 0.0 4.6e-57 192.8 0.0 1.9 3 0 0 3 3 3 1 Domain of unknown function (DUF383) DUF384 PF04064.13 KIY74235.1 - 3.4e-19 68.4 0.3 8.1e-19 67.2 0.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF384) ProRS-C_1 PF09180.11 KIY74237.1 - 1.5e-23 82.7 0.9 3.3e-23 81.7 0.9 1.6 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.25 KIY74237.1 - 6.2e-17 62.1 0.0 1.1e-16 61.3 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KIY74237.1 - 7.6e-17 61.3 0.0 2.1e-16 59.8 0.0 1.8 1 0 0 1 1 1 1 Anticodon binding domain tRNA_edit PF04073.15 KIY74237.1 - 7.1e-10 39.0 0.1 1.4e-09 38.1 0.1 1.4 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain zf-ZPR1 PF03367.13 KIY74237.1 - 0.22 11.4 0.4 0.85 9.5 0.0 2.1 3 0 0 3 3 3 0 ZPR1 zinc-finger domain DUF1708 PF08101.11 KIY74238.1 - 3.4e-24 85.8 0.0 3e-23 82.7 0.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF1708) Myb_DNA-bind_2 PF08914.11 KIY74239.1 - 1.4e-09 37.9 1.6 2.5e-09 37.1 0.7 1.9 2 0 0 2 2 2 1 Rap1 Myb domain Ras PF00071.22 KIY74240.1 - 1.6e-64 216.4 0.0 1.9e-64 216.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KIY74240.1 - 2.7e-34 117.9 0.1 4.7e-34 117.2 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KIY74240.1 - 1.4e-14 53.9 0.1 1.8e-14 53.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KIY74240.1 - 9.7e-06 25.3 0.1 2.3e-05 24.1 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KIY74240.1 - 7.9e-05 22.7 0.0 0.00021 21.3 0.0 1.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KIY74240.1 - 8.7e-05 22.0 0.0 9.9e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KIY74240.1 - 9e-05 22.4 0.0 0.25 11.3 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 KIY74240.1 - 0.0075 16.7 0.0 0.017 15.5 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain FeoB_N PF02421.18 KIY74240.1 - 0.012 15.1 0.0 1.4 8.5 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B SRPRB PF09439.10 KIY74240.1 - 0.034 13.6 0.0 0.046 13.2 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Septin PF00735.18 KIY74240.1 - 0.041 13.2 0.0 0.073 12.3 0.0 1.4 1 0 0 1 1 1 0 Septin AAA_29 PF13555.6 KIY74240.1 - 0.046 13.5 0.2 0.16 11.8 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain CLASP_N PF12348.8 KIY74241.1 - 7.4e-24 84.6 0.0 1.1e-23 84.0 0.0 1.2 1 0 0 1 1 1 1 CLASP N terminal SDA1 PF05285.12 KIY74241.1 - 0.15 11.5 10.0 0.33 10.3 10.0 1.5 1 0 0 1 1 1 0 SDA1 DHC_N1 PF08385.12 KIY74242.1 - 4.9e-124 415.0 13.7 1.3e-123 413.7 5.8 2.9 3 0 0 3 3 3 2 Dynein heavy chain, N-terminal region 1 NPV_P10 PF05531.12 KIY74242.1 - 0.68 10.4 2.6 24 5.5 0.1 3.7 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein BTB PF00651.31 KIY74243.1 - 0.015 15.6 0.0 0.026 14.7 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain PP2C PF00481.21 KIY74244.1 - 4.4e-27 95.3 0.0 6.9e-26 91.4 0.0 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KIY74244.1 - 0.0037 16.9 0.0 0.0095 15.6 0.0 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C YqzE PF14038.6 KIY74245.1 - 4.8 7.3 9.4 7.5 6.6 0.1 2.4 2 0 0 2 2 2 0 YqzE-like protein DUF2076 PF09849.9 KIY74245.1 - 4.9 7.1 11.7 0.53 10.3 5.0 2.3 1 1 2 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2076) Arg_tRNA_synt_N PF03485.16 KIY74246.1 - 0.043 14.4 0.0 0.19 12.4 0.0 1.9 2 0 0 2 2 2 0 Arginyl tRNA synthetase N terminal domain tRNA-synt_2c PF01411.19 KIY74247.1 - 5.2e-216 718.4 0.0 7.5e-216 717.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 KIY74247.1 - 2.4e-16 59.5 0.0 5.3e-16 58.4 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 KIY74247.1 - 6.6e-13 49.3 8.0 1.9e-12 47.8 8.0 1.8 1 0 0 1 1 1 1 DHHA1 domain Cytochrom_B562 PF07361.11 KIY74247.1 - 0.077 13.7 5.4 0.5 11.0 5.4 2.5 1 0 0 1 1 1 0 Cytochrome b562 Ribosomal_L34 PF00468.17 KIY74248.1 - 2.8e-20 72.0 10.1 3.8e-20 71.6 10.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L34 C2-set_2 PF08205.12 KIY74249.1 - 0.025 14.6 1.8 0.033 14.2 1.8 1.3 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain EMG1 PF03587.14 KIY74250.1 - 9.8e-78 260.3 0.0 1.1e-77 260.1 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Aldo_ket_red PF00248.21 KIY74251.1 - 8.7e-45 153.2 0.1 2.7e-34 118.7 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family Ldh_1_C PF02866.18 KIY74254.1 - 1e-46 158.9 0.0 4.8e-46 156.7 0.0 1.9 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 KIY74254.1 - 3.5e-44 150.3 0.2 5.4e-44 149.7 0.2 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KIY74254.1 - 0.0005 19.2 0.0 0.00092 18.3 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 KIY74254.1 - 0.039 14.4 0.0 0.08 13.4 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 KIY74254.1 - 0.04 14.1 0.0 0.083 13.0 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus THF_DHG_CYH_C PF02882.19 KIY74254.1 - 0.064 12.6 0.0 0.26 10.6 0.0 2.0 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ADH_N PF08240.12 KIY74255.1 - 5e-25 87.5 0.8 8.7e-25 86.7 0.8 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KIY74255.1 - 2.6e-12 46.8 0.0 3.9e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KIY74255.1 - 0.011 15.2 0.1 0.19 11.2 0.1 2.2 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus Pex24p PF06398.11 KIY74256.1 - 5.3e-21 75.0 11.8 4.5e-19 68.7 4.6 2.5 2 1 0 2 2 2 2 Integral peroxisomal membrane peroxin TSC22 PF01166.18 KIY74258.1 - 0.0017 18.6 10.9 0.0042 17.3 0.3 3.5 3 1 1 4 4 4 2 TSC-22/dip/bun family HALZ PF02183.18 KIY74258.1 - 0.0018 18.4 5.5 0.018 15.3 0.5 2.7 2 0 0 2 2 2 1 Homeobox associated leucine zipper ZapB PF06005.12 KIY74258.1 - 0.0074 16.7 11.2 0.084 13.3 4.2 3.1 1 1 1 2 2 2 1 Cell division protein ZapB TolA_bind_tri PF16331.5 KIY74258.1 - 0.0076 16.3 8.7 0.18 11.9 6.6 2.5 2 0 0 2 2 2 1 TolA binding protein trimerisation YabA PF06156.13 KIY74258.1 - 0.018 15.7 6.8 0.033 14.8 1.0 2.6 1 1 1 2 2 2 0 Initiation control protein YabA LCD1 PF09798.9 KIY74258.1 - 0.026 13.1 0.1 0.035 12.6 0.1 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein bZIP_1 PF00170.21 KIY74258.1 - 0.046 13.8 2.3 0.24 11.5 0.5 2.3 2 0 0 2 2 2 0 bZIP transcription factor DUF4407 PF14362.6 KIY74258.1 - 0.074 12.4 5.6 0.072 12.4 2.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) NRBF2 PF08961.10 KIY74258.1 - 0.17 11.5 17.3 0.16 11.6 1.3 3.7 2 1 2 4 4 4 0 Nuclear receptor-binding factor 2, autophagy regulator KASH_CCD PF14662.6 KIY74258.1 - 0.52 10.1 12.5 0.43 10.4 10.8 1.6 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH JIP_LZII PF16471.5 KIY74258.1 - 0.92 9.7 6.9 0.8 9.9 0.7 3.1 1 1 2 3 3 3 0 JNK-interacting protein leucine zipper II DUF2205 PF10224.9 KIY74258.1 - 1 9.4 7.0 0.4 10.7 1.4 2.4 2 0 0 2 2 2 0 Short coiled-coil protein DivIC PF04977.15 KIY74258.1 - 1.3 8.9 6.7 2.2 8.1 1.7 2.7 2 1 0 2 2 2 0 Septum formation initiator ASD2 PF08687.11 KIY74258.1 - 1.9 8.0 11.0 0.042 13.4 2.0 2.0 2 0 0 2 2 2 0 Apx/Shroom domain ASD2 Cnn_1N PF07989.11 KIY74258.1 - 3.5 7.8 7.3 16 5.7 2.0 2.9 1 1 2 3 3 3 0 Centrosomin N-terminal motif 1 DUF4140 PF13600.6 KIY74258.1 - 9 6.8 8.1 0.56 10.7 2.0 2.1 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) LRR_4 PF12799.7 KIY74259.1 - 8.4e-11 41.9 10.5 0.00014 22.2 0.8 5.0 2 1 4 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KIY74259.1 - 2.4e-08 33.6 11.7 8.2e-06 25.5 3.8 3.5 2 1 1 3 3 3 2 Leucine rich repeat LRR_9 PF14580.6 KIY74259.1 - 4.9e-05 22.9 0.6 0.00022 20.8 0.3 2.0 2 1 1 3 3 3 1 Leucine-rich repeat Med3 PF11593.8 KIY74259.1 - 0.17 11.0 0.6 0.29 10.3 0.6 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal LRR_6 PF13516.6 KIY74259.1 - 4.6 7.5 8.6 9.7 6.5 0.3 4.6 5 0 0 5 5 5 0 Leucine Rich repeat UBA PF00627.31 KIY74260.1 - 4.6e-30 103.1 8.6 2.8e-15 55.9 0.2 3.1 3 0 0 3 3 3 2 UBA/TS-N domain ubiquitin PF00240.23 KIY74260.1 - 2.8e-20 71.8 0.2 4.8e-20 71.1 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin family XPC-binding PF09280.11 KIY74260.1 - 3.3e-19 68.3 14.9 3.3e-19 68.3 14.9 1.6 2 0 0 2 2 1 1 XPC-binding domain Rad60-SLD PF11976.8 KIY74260.1 - 9.4e-05 22.2 0.3 0.00015 21.5 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like CUE PF02845.16 KIY74260.1 - 0.0023 17.6 0.3 0.045 13.5 0.0 2.8 2 1 1 3 3 3 1 CUE domain Ubiquitin_2 PF14560.6 KIY74260.1 - 0.012 16.0 0.0 0.042 14.3 0.0 1.8 2 0 0 2 2 2 0 Ubiquitin-like domain Ubiquitin_5 PF18037.1 KIY74260.1 - 0.062 13.7 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain RuvA_C PF07499.13 KIY74260.1 - 0.076 13.5 0.1 38 4.8 0.0 3.3 3 0 0 3 3 3 0 RuvA, C-terminal domain Flagellin_IN PF07196.13 KIY74260.1 - 0.12 12.6 0.4 0.23 11.7 0.4 1.4 1 0 0 1 1 1 0 Flagellin hook IN motif UBA_4 PF14555.6 KIY74260.1 - 0.12 12.2 0.1 13 5.7 0.0 3.2 2 1 1 3 3 3 0 UBA-like domain Rad60-SLD_2 PF13881.6 KIY74260.1 - 0.13 12.4 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like WIYLD PF10440.9 KIY74260.1 - 0.18 11.6 0.0 7.7 6.4 0.0 2.3 2 0 0 2 2 2 0 Ubiquitin-binding WIYLD domain RepB PF07506.11 KIY74260.1 - 0.2 11.7 0.1 2 8.4 0.0 2.1 2 0 0 2 2 2 0 RepB plasmid partitioning protein AAA_35 PF14516.6 KIY74260.1 - 0.2 10.4 0.3 0.3 9.9 0.3 1.2 1 0 0 1 1 1 0 AAA-like domain DUF3073 PF11273.8 KIY74261.1 - 0.62 10.8 4.2 1.8 9.3 4.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3073) DUF3712 PF12505.8 KIY74263.1 - 2.9e-120 395.9 51.5 6.6e-26 91.0 0.0 10.9 11 0 0 11 11 11 7 Protein of unknown function (DUF3712) LEA_2 PF03168.13 KIY74263.1 - 1.1e-18 67.6 14.3 0.22 12.1 0.1 11.0 10 0 0 10 10 10 6 Late embryogenesis abundant protein Bactofilin PF04519.13 KIY74263.1 - 0.013 15.8 0.1 0.82 10.0 0.0 3.6 3 0 0 3 3 3 0 Polymer-forming cytoskeletal GFO_IDH_MocA_C PF02894.17 KIY74264.1 - 0.4 10.7 1.4 1 9.4 1.4 1.7 1 1 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain DSPc PF00782.20 KIY74266.1 - 5.5e-06 26.2 0.5 1.8e-05 24.5 0.2 1.9 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KIY74266.1 - 0.001 18.7 0.3 0.0045 16.6 0.2 2.0 2 1 0 2 2 2 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 KIY74266.1 - 0.011 15.4 0.1 0.02 14.6 0.1 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase3 PF13350.6 KIY74266.1 - 0.21 11.6 0.0 0.38 10.7 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family ABC_membrane_2 PF06472.15 KIY74267.1 - 1.7e-74 250.7 0.5 2.7e-74 250.0 0.5 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 KIY74267.1 - 4.8e-16 59.5 0.0 9.6e-16 58.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KIY74267.1 - 0.0077 15.7 0.0 0.57 9.6 0.0 2.1 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KIY74267.1 - 0.081 13.3 0.0 0.24 11.7 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 KIY74267.1 - 0.12 12.3 0.1 0.23 11.3 0.1 1.5 1 0 0 1 1 1 0 NACHT domain RESP18 PF14948.6 KIY74268.1 - 0.039 14.2 0.2 5.3 7.4 0.0 2.7 2 0 0 2 2 2 0 RESP18 domain Chitin_synth_2 PF03142.15 KIY74269.1 - 8e-249 826.6 0.0 1.1e-248 826.2 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 KIY74269.1 - 1.9e-12 47.5 1.7 1.9e-12 47.5 1.7 3.2 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KIY74269.1 - 5.3e-12 46.1 0.1 1.5e-11 44.6 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Cyt-b5 PF00173.28 KIY74269.1 - 3.8e-05 23.8 0.0 0.0055 16.8 0.0 3.3 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain Nuc_sug_transp PF04142.15 KIY74270.1 - 9.1e-93 310.9 5.3 3.3e-84 282.8 3.5 2.0 2 0 0 2 2 2 2 Nucleotide-sugar transporter UAA PF08449.11 KIY74270.1 - 0.0012 18.1 8.0 0.0038 16.5 8.0 1.7 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 KIY74270.1 - 0.0022 18.2 3.7 0.0022 18.2 3.7 3.0 2 1 0 3 3 3 1 EamA-like transporter family PUNUT PF16913.5 KIY74270.1 - 0.0046 16.2 0.5 0.0046 16.2 0.5 1.6 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport TPT PF03151.16 KIY74270.1 - 0.28 10.5 10.9 0.085 12.2 1.4 2.7 2 1 0 2 2 2 0 Triose-phosphate Transporter family DUF4231 PF14015.6 KIY74270.1 - 2 8.9 6.7 0.7 10.4 1.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) DUF3684 PF12449.8 KIY74271.1 - 1.3e-284 947.2 0.0 1.5e-284 946.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.6 KIY74271.1 - 0.056 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HEAT_2 PF13646.6 KIY74271.1 - 0.09 13.2 0.1 0.82 10.1 0.0 2.7 2 0 0 2 2 2 0 HEAT repeats DUF1687 PF07955.11 KIY74272.1 - 8.4e-13 48.9 0.4 1.1e-11 45.3 0.4 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF1687) cIII PF08134.11 KIY74272.1 - 0.051 13.3 0.0 0.099 12.4 0.0 1.4 1 0 0 1 1 1 0 cIII protein family Vac7 PF12751.7 KIY74273.1 - 0.11 11.9 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 Peptidase_C1_2 PF03051.15 KIY74276.1 - 3.1e-158 527.1 0.0 3.7e-158 526.9 0.0 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.23 KIY74276.1 - 1.2e-06 28.8 0.1 0.02 15.0 0.0 2.7 2 1 0 2 2 2 2 Papain family cysteine protease Tup_N PF08581.10 KIY74278.1 - 3.2e-05 24.2 1.6 3.2e-05 24.2 1.6 6.5 6 3 3 9 9 9 1 Tup N-terminal SHIPPO-rpt PF07004.12 KIY74278.1 - 0.018 15.9 0.8 0.053 14.5 0.0 2.1 2 0 0 2 2 2 0 Sperm-tail PG-rich repeat DUF2508 PF10704.9 KIY74278.1 - 0.12 12.6 0.1 0.12 12.6 0.1 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF2508) GIT_CC PF16559.5 KIY74278.1 - 0.19 11.6 0.1 0.19 11.6 0.1 6.1 6 1 0 6 6 6 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF1242 PF06842.12 KIY74279.1 - 6.8e-19 67.4 2.2 9.6e-19 66.9 2.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) DUF805 PF05656.14 KIY74279.1 - 0.11 12.9 0.4 0.12 12.8 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF805) LST1 PF05083.13 KIY74279.1 - 1.7 8.9 3.9 1.5 9.2 2.4 1.6 1 1 1 2 2 2 0 LST-1 protein RPA43_OB PF17875.1 KIY74280.1 - 9.3e-24 84.4 0.0 9.3e-24 84.4 0.0 3.2 3 1 0 3 3 3 1 RPA43 OB domain in RNA Pol I SHS2_Rpb7-N PF03876.17 KIY74280.1 - 3.6e-07 30.4 0.0 5.8e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 YL1 PF05764.13 KIY74280.1 - 0.015 15.4 4.1 0.015 15.4 4.1 2.0 2 0 0 2 2 2 0 YL1 nuclear protein Pam16 PF03656.13 KIY74281.1 - 6.8e-21 74.6 0.2 7.9e-21 74.4 0.2 1.0 1 0 0 1 1 1 1 Pam16 DUF3419 PF11899.8 KIY74282.1 - 1.9e-141 471.8 0.0 2.3e-141 471.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_25 PF13649.6 KIY74282.1 - 5e-08 33.5 0.0 1.7e-07 31.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KIY74282.1 - 1.7e-06 28.0 0.0 4.3e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KIY74282.1 - 4.7e-05 24.0 0.0 0.00015 22.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KIY74282.1 - 0.0002 22.1 0.0 0.0005 20.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KIY74282.1 - 0.00054 19.4 0.0 0.0014 18.0 0.0 1.7 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KIY74282.1 - 0.0017 18.2 0.0 0.0029 17.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KIY74282.1 - 0.06 12.8 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase RhoGAP PF00620.27 KIY74283.1 - 1.8e-39 135.0 0.0 4.2e-39 133.8 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 KIY74283.1 - 9.5e-13 48.2 25.9 9.1e-08 32.2 8.0 2.7 3 0 0 3 3 2 2 LIM domain C1_1 PF00130.22 KIY74283.1 - 2.3e-06 27.4 8.2 2.3e-06 27.4 8.2 4.0 2 1 3 5 5 4 2 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 KIY74283.1 - 0.011 16.0 2.3 0.011 16.0 2.3 3.9 3 2 1 4 4 3 0 C1 domain Gp-FAR-1 PF05823.12 KIY74283.1 - 0.018 15.4 0.8 0.22 11.9 0.1 2.7 2 1 1 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Fungal_TACC PF12709.7 KIY74283.1 - 0.18 12.2 3.6 9.5 6.7 0.1 3.0 3 0 0 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins DUF4407 PF14362.6 KIY74283.1 - 0.32 10.3 8.9 1.7 7.9 9.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Seryl_tRNA_N PF02403.22 KIY74283.1 - 0.61 10.3 7.7 0.12 12.6 0.4 3.0 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Baculo_PEP_C PF04513.12 KIY74283.1 - 2.5 8.2 6.3 1.9 8.5 2.9 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus YlqD PF11068.8 KIY74283.1 - 5.2 7.4 9.3 0.32 11.4 2.9 2.2 2 1 0 2 2 2 0 YlqD protein GAS PF13851.6 KIY74283.1 - 6.9 6.0 13.3 22 4.4 12.9 1.8 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Ribosomal_L29 PF00831.23 KIY74283.1 - 9.1 6.3 7.7 0.69 9.9 1.2 2.6 3 0 0 3 3 3 0 Ribosomal L29 protein BTB PF00651.31 KIY74284.1 - 2e-12 47.3 0.0 3.1e-05 24.1 0.0 2.8 3 0 0 3 3 3 2 BTB/POZ domain Complex1_LYR_2 PF13233.6 KIY74285.1 - 9.4e-19 68.0 0.0 1.2e-18 67.6 0.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 KIY74285.1 - 4.7e-11 42.6 0.0 7.4e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) zf-U1 PF06220.12 KIY74286.1 - 7.6e-11 41.6 1.1 1.1e-10 41.0 1.1 1.3 1 0 0 1 1 1 1 U1 zinc finger GvpH PF05455.11 KIY74286.1 - 0.0058 16.7 0.4 0.012 15.7 0.4 1.6 1 0 0 1 1 1 1 GvpH CDK2AP PF09806.9 KIY74286.1 - 3.5 7.6 8.8 0.093 12.8 2.3 1.6 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein MFS_1 PF07690.16 KIY74287.1 - 3.6e-15 55.8 34.0 7.5e-15 54.7 32.5 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily LRR_4 PF12799.7 KIY74288.1 - 4e-20 71.6 22.1 2.2e-06 27.9 2.0 7.6 8 0 0 8 8 8 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KIY74288.1 - 1.6e-12 46.9 13.3 1.5e-08 34.3 3.8 7.7 7 2 1 8 8 8 4 Leucine rich repeat LRR_6 PF13516.6 KIY74288.1 - 3e-06 26.8 22.8 7.2 6.9 0.0 8.8 9 0 0 9 9 9 5 Leucine Rich repeat LRR_9 PF14580.6 KIY74288.1 - 4.4e-05 23.0 1.9 0.014 14.9 0.4 3.6 5 0 0 5 5 5 2 Leucine-rich repeat LRR_1 PF00560.33 KIY74288.1 - 5.1e-05 23.3 25.4 2.1 9.2 0.0 9.3 10 0 0 10 10 10 3 Leucine Rich Repeat PRP21_like_P PF12230.8 KIY74288.1 - 8.8 6.1 7.9 2.1 8.2 1.9 2.2 2 0 0 2 2 2 0 Pre-mRNA splicing factor PRP21 like protein Pkinase PF00069.25 KIY74289.1 - 5.7e-65 219.3 0.0 7.5e-65 218.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY74289.1 - 6.2e-39 133.8 0.0 8.5e-39 133.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY74289.1 - 2.2e-05 23.9 0.0 6.2e-05 22.5 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KIY74289.1 - 0.0056 16.1 0.0 0.0098 15.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KIY74289.1 - 0.022 14.4 0.1 0.06 13.0 0.0 1.7 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 KIY74289.1 - 0.043 12.6 1.9 0.084 11.6 1.9 1.5 1 1 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 KIY74289.1 - 0.046 13.3 0.0 0.17 11.5 0.0 1.7 1 1 1 2 2 2 0 RIO1 family APH PF01636.23 KIY74289.1 - 0.073 13.0 0.2 0.82 9.5 0.1 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family SET PF00856.28 KIY74290.1 - 2e-13 51.1 0.1 6.5e-13 49.4 0.1 1.9 2 1 0 2 2 2 1 SET domain SAF PF08666.12 KIY74290.1 - 0.049 14.3 0.0 1.8 9.2 0.0 2.5 2 0 0 2 2 2 0 SAF domain DUF4775 PF16001.5 KIY74290.1 - 0.16 11.4 0.2 0.26 10.6 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4775) ARD PF03079.14 KIY74291.1 - 0.002 18.3 7.2 0.0026 17.9 7.2 1.2 1 0 0 1 1 1 1 ARD/ARD' family Macoilin PF09726.9 KIY74291.1 - 0.012 14.2 5.0 0.014 14.0 5.0 1.1 1 0 0 1 1 1 0 Macoilin family DUF2813 PF11398.8 KIY74291.1 - 0.061 12.6 3.7 0.069 12.4 3.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2813) TetR_C_24 PF17932.1 KIY74291.1 - 0.07 13.4 0.9 0.097 12.9 0.9 1.2 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Tho2 PF11262.8 KIY74291.1 - 0.079 12.1 5.4 0.093 11.9 5.4 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Alpha_kinase PF02816.18 KIY74291.1 - 0.089 12.9 3.1 0.11 12.6 3.1 1.1 1 0 0 1 1 1 0 Alpha-kinase family Prismane PF03063.20 KIY74291.1 - 0.091 11.4 3.5 0.096 11.4 3.5 1.0 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family AAA-ATPase_like PF09820.9 KIY74291.1 - 0.095 12.1 2.7 0.12 11.8 2.7 1.1 1 0 0 1 1 1 0 Predicted AAA-ATPase PriA_C PF18074.1 KIY74291.1 - 0.14 13.0 1.3 0.2 12.5 1.3 1.2 1 0 0 1 1 1 0 Primosomal protein N C-terminal domain Myb_DNA-binding PF00249.31 KIY74292.1 - 1.4e-08 34.8 0.1 2.3e-08 34.1 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KIY74292.1 - 0.00029 21.0 0.1 0.00065 19.9 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain TRP PF06011.12 KIY74293.1 - 1.7e-83 280.7 12.7 2.4e-83 280.2 12.7 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KIY74293.1 - 4.1e-28 98.5 0.1 6.1e-28 97.9 0.1 1.3 1 0 0 1 1 1 1 ML-like domain Orf78 PF06024.12 KIY74293.1 - 0.036 14.4 0.8 1.6 9.1 0.0 2.9 3 0 0 3 3 3 0 Orf78 (ac78) SLATT_4 PF18186.1 KIY74293.1 - 0.19 11.3 0.0 0.69 9.5 0.0 1.9 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 4 DUF4834 PF16118.5 KIY74293.1 - 0.24 12.4 0.6 30 5.6 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF2678 PF10856.8 KIY74293.1 - 5.8 6.9 10.8 0.2 11.6 3.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2678) OSCP PF00213.18 KIY74294.1 - 2.5e-41 141.6 1.4 2.9e-41 141.5 1.4 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit T3SS_needle_E PF08988.10 KIY74294.1 - 0.25 11.5 1.4 18 5.6 0.1 2.4 2 0 0 2 2 2 0 Type III secretion system, cytoplasmic E component of needle ICMT PF04140.14 KIY74295.1 - 1.4e-14 54.2 0.1 3.4e-13 49.8 0.1 2.3 1 1 1 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KIY74295.1 - 4.5e-11 43.1 1.3 8.8e-11 42.1 1.2 1.6 1 1 0 1 1 1 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 KIY74295.1 - 0.00018 20.5 0.5 0.00023 20.0 0.5 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 KIY74295.1 - 0.0015 18.1 0.3 0.0024 17.5 0.3 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) Clathrin_propel PF01394.20 KIY74295.1 - 0.036 14.4 0.0 0.083 13.2 0.0 1.5 1 0 0 1 1 1 0 Clathrin propeller repeat MgsA_C PF12002.8 KIY74296.1 - 7.5e-56 188.6 0.0 1.2e-55 188.0 0.0 1.3 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 KIY74296.1 - 3.4e-19 69.0 0.2 1.7e-18 66.7 0.1 2.2 2 0 0 2 2 2 1 AAA C-terminal domain AAA PF00004.29 KIY74296.1 - 5.4e-17 62.4 0.0 1.5e-16 61.0 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KIY74296.1 - 2.6e-16 59.8 0.0 4.3e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KIY74296.1 - 6.6e-07 29.4 0.1 1.8e-05 24.8 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KIY74296.1 - 1.2e-06 29.0 1.2 0.0022 18.4 0.0 2.8 2 1 1 3 3 3 2 AAA ATPase domain Mg_chelatase PF01078.21 KIY74296.1 - 5.2e-06 26.0 0.0 0.02 14.3 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 KIY74296.1 - 8.9e-06 26.0 0.2 0.0012 19.1 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.14 KIY74296.1 - 0.00015 22.0 0.0 0.00027 21.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Sigma54_activat PF00158.26 KIY74296.1 - 0.00017 21.4 0.0 0.0069 16.1 0.0 2.3 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_14 PF13173.6 KIY74296.1 - 0.00019 21.4 0.0 0.00033 20.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KIY74296.1 - 0.0015 18.7 0.0 0.0028 17.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.6 KIY74296.1 - 0.0054 16.8 0.0 0.014 15.5 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain RNA_helicase PF00910.22 KIY74296.1 - 0.021 15.2 0.0 0.054 13.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 KIY74296.1 - 0.024 15.2 0.0 0.043 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KIY74296.1 - 0.028 14.6 0.0 0.056 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KIY74296.1 - 0.049 12.8 0.0 0.59 9.3 0.0 2.1 1 1 1 2 2 2 0 NB-ARC domain TIP49 PF06068.13 KIY74296.1 - 0.06 12.5 0.0 0.16 11.1 0.0 1.5 1 1 0 1 1 1 0 TIP49 P-loop domain Viral_helicase1 PF01443.18 KIY74296.1 - 0.069 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.27 KIY74296.1 - 0.11 13.1 0.0 0.29 11.7 0.0 1.6 1 1 0 1 1 1 0 ABC transporter AAA_17 PF13207.6 KIY74296.1 - 0.11 12.9 0.2 0.31 11.4 0.0 1.9 3 0 0 3 3 1 0 AAA domain Rad17 PF03215.15 KIY74296.1 - 0.14 12.0 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain DUF815 PF05673.13 KIY74296.1 - 0.15 11.2 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_30 PF13604.6 KIY74296.1 - 0.16 11.7 0.1 7.7 6.2 0.1 2.3 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.6 KIY74296.1 - 0.19 11.4 0.0 0.31 10.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain DnaJ PF00226.31 KIY74297.1 - 1.3e-13 50.8 0.1 2.4e-13 50.0 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain PRIMA1 PF16101.5 KIY74297.1 - 0.19 11.8 0.2 4.4 7.4 0.1 2.3 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Peptidase_C15 PF01470.17 KIY74299.1 - 0.022 14.9 0.0 0.56 10.3 0.0 2.7 3 0 0 3 3 3 0 Pyroglutamyl peptidase eIF-3c_N PF05470.12 KIY74300.1 - 1.4e-172 575.1 14.3 1.4e-172 575.1 14.3 3.0 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 KIY74300.1 - 9.5e-15 55.0 0.0 3.8e-14 53.1 0.0 2.1 2 0 0 2 2 2 1 PCI domain T7SS_ESX_EspC PF10824.8 KIY74300.1 - 0.019 15.4 0.3 2.6 8.6 0.0 2.7 2 0 0 2 2 2 0 Excreted virulence factor EspC, type VII ESX diderm DUF2408 PF10303.9 KIY74300.1 - 0.37 11.4 3.3 2.2 8.9 0.1 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF2408) Peptidase_S58 PF03576.14 KIY74303.1 - 3e-82 276.5 0.0 3.5e-82 276.3 0.0 1.0 1 0 0 1 1 1 1 Peptidase family S58 NIF PF03031.18 KIY74304.1 - 4.9e-53 179.1 0.1 6.4e-53 178.7 0.1 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD PF12710.7 KIY74304.1 - 0.04 14.3 0.1 0.36 11.2 0.0 2.0 1 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase bZIP_1 PF00170.21 KIY74305.1 - 3.9e-06 26.8 10.5 1.3e-05 25.2 10.5 1.8 1 1 0 1 1 1 1 bZIP transcription factor HeH PF12949.7 KIY74305.1 - 0.064 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 HeH/LEM domain FlgN PF05130.12 KIY74305.1 - 0.27 11.8 3.5 0.35 11.4 3.5 1.1 1 0 0 1 1 1 0 FlgN protein CCDC53 PF10152.9 KIY74305.1 - 6.6 7.1 6.6 2 8.8 0.1 2.4 2 1 0 2 2 2 0 Subunit CCDC53 of WASH complex TPP1 PF10341.9 KIY74306.1 - 0.004 17.1 0.1 0.0094 15.9 0.1 1.6 1 0 0 1 1 1 1 Shelterin complex subunit, TPP1/ACD UPF0139 PF03669.13 KIY74307.1 - 0.068 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0139) Spectrin PF00435.21 KIY74307.1 - 0.11 13.0 0.2 0.11 13.0 0.2 2.4 2 0 0 2 2 2 0 Spectrin repeat Spc7 PF08317.11 KIY74307.1 - 0.5 9.2 22.8 0.18 10.6 12.9 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF3450 PF11932.8 KIY74307.1 - 0.63 9.3 15.0 0.1 11.9 7.1 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF3450) KASH_CCD PF14662.6 KIY74307.1 - 0.74 9.6 15.0 0.14 12.0 11.0 1.7 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH DUF1043 PF06295.12 KIY74307.1 - 1.2 9.2 7.0 3.5 7.7 0.4 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) ADIP PF11559.8 KIY74307.1 - 1.8 8.6 23.5 4 7.5 14.8 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Tup_N PF08581.10 KIY74307.1 - 2.2 8.7 7.4 2.1 8.7 0.1 3.0 3 0 0 3 3 3 0 Tup N-terminal Fez1 PF06818.15 KIY74307.1 - 2.7 8.4 18.5 2.3 8.6 1.5 2.2 1 1 1 2 2 2 0 Fez1 CREPT PF16566.5 KIY74307.1 - 3 8.0 9.9 2 8.6 2.7 3.1 2 1 1 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour Fib_alpha PF08702.10 KIY74307.1 - 4.6 7.4 12.0 2.1 8.5 7.8 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Golgin_A5 PF09787.9 KIY74307.1 - 5.5 6.4 19.2 25 4.2 18.6 1.9 1 1 0 1 1 1 0 Golgin subfamily A member 5 ATG16 PF08614.11 KIY74307.1 - 6.5 6.9 26.1 1.5 9.0 16.8 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF16 PF01519.16 KIY74307.1 - 7.3 7.1 6.7 32 5.1 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF16 LMBR1 PF04791.16 KIY74307.1 - 8.2 5.2 5.2 15 4.3 5.2 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein PALP PF00291.25 KIY74308.1 - 8.3e-72 242.1 0.7 1e-71 241.8 0.7 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Arf PF00025.21 KIY74309.1 - 1.5e-77 259.0 0.0 1.7e-77 258.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KIY74309.1 - 2.2e-15 56.9 0.1 3.1e-15 56.5 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KIY74309.1 - 4.4e-13 49.1 0.0 4.6e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 KIY74309.1 - 8e-12 45.0 1.4 1.7e-07 30.8 0.2 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 KIY74309.1 - 1.1e-11 44.5 0.0 1.4e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KIY74309.1 - 1.7e-09 37.4 0.0 2.2e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KIY74309.1 - 0.0001 22.4 0.0 0.00017 21.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 KIY74309.1 - 0.017 14.4 0.1 0.026 13.9 0.1 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase NIF PF03031.18 KIY74310.1 - 1e-53 181.3 0.1 1.4e-53 180.9 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD PF12710.7 KIY74310.1 - 0.035 14.5 0.1 0.17 12.3 0.0 1.9 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Ribosomal_S5 PF00333.20 KIY74311.1 - 5.9e-28 96.6 1.2 5.9e-28 96.6 1.2 2.0 3 0 0 3 3 3 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 KIY74311.1 - 1.4e-23 82.1 0.1 2.3e-23 81.4 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain EB PF01683.18 KIY74312.1 - 0.0063 16.8 32.2 0.23 11.8 5.3 4.4 3 2 1 4 4 4 4 EB module MWFE PF15879.5 KIY74312.1 - 0.06 13.5 0.2 0.22 11.7 0.1 1.9 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase MWFE subunit Dickkopf_N PF04706.12 KIY74312.1 - 1.3 9.6 38.3 0.1 13.1 8.7 4.4 4 0 0 4 4 4 0 Dickkopf N-terminal cysteine-rich region DUF1771 PF08590.10 KIY74313.1 - 5.2e-23 81.2 7.9 5.2e-23 81.2 7.9 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.21 KIY74313.1 - 7.3e-13 48.7 0.4 2e-12 47.3 0.4 1.8 1 0 0 1 1 1 1 Smr domain DUF4407 PF14362.6 KIY74313.1 - 0.011 15.1 11.2 0.015 14.7 11.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TFIIA PF03153.13 KIY74313.1 - 0.025 14.6 18.3 0.029 14.4 18.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GatB_Yqey PF02637.18 KIY74313.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 GatB domain SOG2 PF10428.9 KIY74313.1 - 0.65 9.1 5.9 0.79 8.9 5.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein SRP-alpha_N PF04086.13 KIY74313.1 - 1.9 8.4 14.9 2.4 8.0 14.9 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Zip PF02535.22 KIY74313.1 - 2.7 7.1 5.4 3.5 6.8 5.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter UPF0524 PF15823.5 KIY74313.1 - 2.9 7.2 7.1 3.5 7.0 6.6 1.3 1 1 0 1 1 1 0 UPF0524 of C3orf70 ODC_AZ PF02100.17 KIY74314.1 - 2.1e-14 53.4 0.0 3.2e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme KHA PF11834.8 KIY74314.1 - 0.16 12.1 0.0 0.48 10.5 0.0 1.8 1 1 0 1 1 1 0 KHA, dimerisation domain of potassium ion channel Glyco_hydro_61 PF03443.14 KIY74315.1 - 2.2e-51 174.7 0.0 2.5e-51 174.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Formin_GBD_N PF18382.1 KIY74316.1 - 0.019 15.4 0.0 0.042 14.3 0.0 1.6 1 0 0 1 1 1 0 Formin N-terminal GTPase-binding domain PAC2 PF09754.9 KIY74317.1 - 6.2e-25 88.5 0.0 1e-24 87.7 0.0 1.3 1 1 0 1 1 1 1 PAC2 family YjeF_N PF03853.15 KIY74317.1 - 0.14 12.0 0.0 0.49 10.3 0.0 1.9 2 1 0 2 2 2 0 YjeF-related protein N-terminus NUC173 PF08161.12 KIY74318.1 - 1.1e-54 185.2 0.2 4.3e-53 180.0 0.0 2.7 2 0 0 2 2 2 1 NUC173 domain HEAT PF02985.22 KIY74318.1 - 0.0021 18.1 5.1 0.46 10.9 0.0 4.3 5 0 0 5 5 5 2 HEAT repeat Ribosomal_S13_N PF08069.12 KIY74318.1 - 0.097 12.7 0.2 9.3 6.4 0.0 3.0 3 0 0 3 3 3 0 Ribosomal S13/S15 N-terminal domain HicA_toxin PF07927.12 KIY74321.1 - 5.4e-07 29.6 0.0 1.8e-06 27.8 0.0 2.0 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, DUF3245 PF11595.8 KIY74321.1 - 0.006 17.1 7.1 0.006 17.1 7.1 3.3 3 1 1 4 4 4 1 Protein of unknown function (DUF3245) Ndc1_Nup PF09531.10 KIY74321.1 - 8.8 4.9 11.5 16 4.0 11.5 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Zip PF02535.22 KIY74322.1 - 0.13 11.4 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter ILVD_EDD PF00920.21 KIY74323.1 - 2.6e-204 679.7 0.0 2.9e-204 679.5 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family TPR_1 PF00515.28 KIY74324.1 - 5.4e-16 57.7 0.0 7.7e-05 22.3 0.0 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KIY74324.1 - 2.1e-14 52.4 0.5 0.0012 18.8 0.1 4.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 KIY74324.1 - 1.9e-10 41.2 8.0 5.1e-06 27.0 0.0 4.5 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 KIY74324.1 - 7.9e-08 31.9 0.3 0.53 10.6 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 KIY74324.1 - 8.1e-07 28.6 1.3 0.0011 18.6 0.1 3.3 3 1 0 3 3 3 2 TPR repeat TPR_7 PF13176.6 KIY74324.1 - 1.2e-06 28.1 0.1 2.1 8.6 0.1 4.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 KIY74324.1 - 1.4e-06 28.7 13.7 0.077 13.9 0.1 6.1 5 2 2 7 7 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 KIY74324.1 - 1.7e-05 25.2 3.0 0.039 14.5 0.1 4.2 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 KIY74324.1 - 0.00044 20.5 10.2 0.022 15.1 0.8 4.4 3 1 2 5 5 4 3 Tetratricopeptide repeat TPR_15 PF13429.6 KIY74324.1 - 0.0011 18.2 0.4 0.84 8.8 0.0 2.6 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 KIY74324.1 - 0.0026 18.0 0.0 5.7 7.6 0.1 4.0 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 KIY74324.1 - 0.013 16.1 1.1 34 5.4 0.0 4.8 4 1 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KIY74324.1 - 0.028 14.6 0.9 0.23 11.7 0.1 2.6 2 1 1 3 3 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Coatomer_E PF04733.14 KIY74324.1 - 0.055 12.9 0.1 0.26 10.7 0.0 2.0 2 0 0 2 2 2 0 Coatomer epsilon subunit TPR_10 PF13374.6 KIY74324.1 - 0.092 12.7 2.5 24 5.0 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 KIY74324.1 - 0.12 12.5 2.7 2.3 8.4 0.1 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat ETF PF01012.21 KIY74325.1 - 2.9e-36 125.0 1.8 4.8e-36 124.4 1.8 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 KIY74325.1 - 9.3e-32 108.9 0.1 1.9e-31 107.9 0.1 1.6 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain ATP_transf PF09830.9 KIY74326.1 - 1.4e-22 79.6 0.0 3.3e-22 78.4 0.0 1.7 2 0 0 2 2 2 1 ATP adenylyltransferase DUF4922 PF16269.5 KIY74326.1 - 0.00073 19.4 0.0 0.002 17.9 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4922) DUF4931 PF16285.5 KIY74326.1 - 0.0038 16.6 0.0 0.011 15.1 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4931) HIT PF01230.23 KIY74326.1 - 0.03 15.1 0.0 0.15 12.8 0.0 2.0 2 0 0 2 2 2 0 HIT domain F-box-like PF12937.7 KIY74327.1 - 0.027 14.4 0.1 0.036 14.0 0.1 1.2 1 0 0 1 1 1 0 F-box-like VanZ PF04892.12 KIY74329.1 - 2.3e-05 25.0 0.8 3.4e-05 24.5 0.8 1.3 1 0 0 1 1 1 1 VanZ like family Promethin PF16015.5 KIY74329.1 - 0.019 14.9 0.5 0.019 14.9 0.5 1.9 1 1 1 2 2 2 0 Promethin TcpE PF12648.7 KIY74329.1 - 0.48 11.0 3.3 0.55 10.8 2.7 1.4 1 1 0 1 1 1 0 TcpE family Dioxygenase_C PF00775.21 KIY74330.1 - 5.7e-08 32.4 0.0 1.2e-07 31.3 0.0 1.6 1 1 0 1 1 1 1 Dioxygenase MFS_1 PF07690.16 KIY74331.1 - 1.8e-32 112.7 17.7 1.8e-32 112.7 17.7 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KIY74331.1 - 3.6e-12 45.9 13.6 8.3e-12 44.7 13.6 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 KIY74331.1 - 2.2e-06 26.4 0.3 4.8e-06 25.3 0.3 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Melibiase_2 PF16499.5 KIY74332.1 - 1.9e-49 168.4 7.8 3.5e-49 167.5 7.8 1.4 1 1 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 KIY74332.1 - 7.8e-10 38.7 0.7 3.6e-09 36.6 0.0 2.5 3 0 0 3 3 3 1 Alpha galactosidase C-terminal beta sandwich domain CBM_1 PF00734.18 KIY74332.1 - 2.7e-07 30.4 12.3 2.7e-07 30.4 12.3 2.4 2 1 0 2 2 2 1 Fungal cellulose binding domain Melibiase PF02065.18 KIY74332.1 - 1.5e-06 27.4 0.1 3.6e-06 26.2 0.0 1.6 2 0 0 2 2 2 1 Melibiase Phosducin PF02114.16 KIY74333.1 - 2.3e-15 56.3 0.3 2.3e-07 30.1 0.0 3.1 2 1 1 3 3 3 3 Phosducin TMEM247 PF15444.6 KIY74333.1 - 0.035 14.2 3.1 0.051 13.6 3.1 1.2 1 0 0 1 1 1 0 Transmembrane protein 247 Peptidase_C14 PF00656.22 KIY74334.1 - 1.9e-09 37.9 0.0 5.4e-09 36.4 0.0 1.7 1 1 0 1 1 1 1 Caspase domain APG6 PF04111.12 KIY74335.1 - 2.8e-70 235.9 0.0 4.5e-70 235.2 0.0 1.3 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 KIY74335.1 - 1.2e-27 97.1 22.1 2e-27 96.3 22.1 1.4 1 0 0 1 1 1 1 Apg6 coiled-coil region Hairy_orange PF07527.13 KIY74335.1 - 0.045 14.0 0.0 12 6.2 0.0 2.6 2 0 0 2 2 2 0 Hairy Orange GCS PF03074.16 KIY74336.1 - 4.5e-173 575.7 0.0 5.8e-173 575.4 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase GCS2 PF04107.13 KIY74336.1 - 0.035 13.5 0.0 0.079 12.3 0.0 1.5 1 0 0 1 1 1 0 Glutamate-cysteine ligase family 2(GCS2) DUF4460 PF14687.6 KIY74336.1 - 0.11 12.5 0.0 0.69 10.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4460) ATP-synt_DE_N PF02823.16 KIY74337.1 - 2.6e-16 59.3 0.1 3.9e-16 58.7 0.1 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Velvet PF11754.8 KIY74338.1 - 3.4e-20 73.0 0.0 1.5e-10 41.5 0.0 2.0 1 1 1 2 2 2 2 Velvet factor Smr PF01713.21 KIY74339.1 - 1.2e-10 41.6 0.2 1.4e-10 41.4 0.2 1.0 1 0 0 1 1 1 1 Smr domain GatB_Yqey PF02637.18 KIY74339.1 - 0.062 13.2 0.2 0.071 13.0 0.2 1.1 1 0 0 1 1 1 0 GatB domain Chitin_synth_1 PF01644.17 KIY74340.1 - 4.7e-68 228.3 0.0 6.7e-68 227.8 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.15 KIY74340.1 - 1.6e-22 79.8 1.5 1.4e-15 56.9 0.0 2.4 2 0 0 2 2 2 2 Chitin synthase Chitin_synth_1N PF08407.11 KIY74340.1 - 5.5e-19 67.9 0.1 1.4e-18 66.6 0.1 1.8 1 0 0 1 1 1 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.6 KIY74340.1 - 1e-09 38.6 0.3 1e-09 38.6 0.3 3.0 3 1 0 3 3 3 1 Glycosyl transferase family group 2 DUF1720 PF08226.11 KIY74340.1 - 0.64 10.5 8.7 1.3 9.5 8.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1720) Stealth_CR2 PF11380.8 KIY74341.1 - 1.9e-11 44.1 0.3 2.1e-07 31.1 0.0 2.9 3 1 0 3 3 3 2 Stealth protein CR2, conserved region 2 Stealth_CR1 PF17101.5 KIY74341.1 - 5.6e-06 26.0 4.7 1.2e-05 25.0 4.7 1.6 1 0 0 1 1 1 1 Stealth protein CR1, conserved region 1 Stealth_CR3 PF17102.5 KIY74341.1 - 6.8e-05 22.7 2.6 0.00045 20.1 3.1 2.2 2 0 0 2 2 2 1 Stealth protein CR3, conserved region 3 Stealth_CR4 PF17103.5 KIY74341.1 - 0.035 14.0 0.0 0.11 12.4 0.0 1.8 1 0 0 1 1 1 0 Stealth protein CR4, conserved region 4 GILT PF03227.16 KIY74342.1 - 3.3e-13 49.8 0.2 3.3e-13 49.8 0.2 1.6 2 0 0 2 2 2 1 Gamma interferon inducible lysosomal thiol reductase (GILT) Rad9 PF04139.13 KIY74343.1 - 5.7e-48 163.6 0.0 7e-48 163.3 0.0 1.1 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.16 KIY74343.1 - 0.00045 19.4 0.0 0.00073 18.7 0.0 1.3 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 CTP_synth_N PF06418.14 KIY74344.1 - 3.1e-120 400.4 0.3 4.2e-120 400.0 0.3 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 KIY74344.1 - 2.1e-50 171.1 0.0 3.5e-50 170.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KIY74344.1 - 0.002 17.9 0.2 0.022 14.5 0.2 2.2 1 1 0 1 1 1 1 Peptidase C26 zf-4CXXC_R1 PF10497.9 KIY74346.1 - 1e-06 28.8 13.7 2.2e-06 27.8 13.7 1.5 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 WSD PF15613.6 KIY74346.1 - 0.00064 20.2 0.1 0.0031 18.0 0.1 2.2 1 1 0 1 1 1 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif Tim17 PF02466.19 KIY74347.1 - 2.9e-30 104.9 8.9 3.8e-30 104.5 8.9 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Pyrid_ox_like PF16242.5 KIY74348.1 - 4.7e-30 104.2 0.1 6.7e-30 103.6 0.1 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like Putative_PNPOx PF01243.20 KIY74348.1 - 5e-13 49.1 0.0 1e-12 48.0 0.0 1.5 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase DUF4981 PF16353.5 KIY74348.1 - 0.14 12.7 0.0 0.24 11.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function(DUF4981) IBR PF01485.21 KIY74350.1 - 5.7e-09 36.1 28.7 1.4e-05 25.2 5.0 3.4 3 0 0 3 3 3 3 IBR domain, a half RING-finger domain zf-RING_14 PF17978.1 KIY74350.1 - 0.0035 17.7 0.9 0.0035 17.7 0.9 2.5 2 1 1 3 3 3 1 RING/Ubox like zinc-binding domain Glyco_hydro_47 PF01532.20 KIY74351.1 - 1.9e-130 435.9 1.8 2.1e-130 435.7 1.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_76 PF03663.14 KIY74351.1 - 0.00074 19.1 8.4 0.01 15.4 2.7 2.4 2 0 0 2 2 2 2 Glycosyl hydrolase family 76 Histone PF00125.24 KIY74352.1 - 1.2e-49 168.1 3.9 1.3e-49 167.9 3.9 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KIY74352.1 - 2.5e-05 24.6 0.1 4.1e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KIY74352.1 - 9.6e-05 22.5 1.2 9.9e-05 22.4 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 KIY74352.1 - 0.0014 18.9 0.1 0.0014 18.9 0.1 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PAF PF15715.5 KIY74352.1 - 0.0025 18.4 2.1 0.0032 18.0 2.1 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain Bromo_TP PF07524.13 KIY74352.1 - 0.084 12.9 0.1 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 Bromodomain associated TFIID-31kDa PF02291.15 KIY74352.1 - 0.092 12.8 0.2 0.17 11.9 0.1 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Ank_5 PF13857.6 KIY74353.1 - 3.8e-11 43.0 0.7 1.1e-07 32.0 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) TIG PF01833.24 KIY74353.1 - 5e-10 39.3 0.3 1.3e-09 37.9 0.3 1.8 1 0 0 1 1 1 1 IPT/TIG domain Ank_2 PF12796.7 KIY74353.1 - 1.2e-09 38.6 0.0 2.5e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KIY74353.1 - 5.8e-09 36.0 0.2 0.00037 20.8 0.2 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 KIY74353.1 - 6.2e-08 32.3 0.1 0.0078 16.6 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 KIY74353.1 - 4.2e-07 30.4 0.1 8.9e-06 26.2 0.1 3.0 1 1 2 3 3 3 1 Ankyrin repeats (many copies) 2OG-FeII_Oxy_3 PF13640.6 KIY74355.1 - 1.6e-07 32.1 0.1 2.8e-07 31.4 0.1 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PIG-H PF10181.9 KIY74356.1 - 1.3e-21 76.2 0.0 3.1e-21 75.0 0.0 1.6 2 0 0 2 2 2 1 GPI-GlcNAc transferase complex, PIG-H component Cellulase PF00150.18 KIY74357.1 - 4.6e-32 111.6 4.7 7.4e-32 110.9 4.7 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) GalKase_gal_bdg PF10509.9 KIY74358.1 - 8.2e-23 79.7 0.6 1.4e-22 79.0 0.0 1.7 2 0 0 2 2 2 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 KIY74358.1 - 2.1e-13 50.3 1.4 2.1e-13 50.3 1.4 2.2 3 0 0 3 3 3 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KIY74358.1 - 2.7e-13 50.1 0.1 7.6e-13 48.6 0.1 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal NUP50 PF08911.11 KIY74359.1 - 2.1e-16 60.3 0.7 2.1e-16 60.3 0.7 5.6 4 2 0 4 4 4 1 NUP50 (Nucleoporin 50 kDa) Ran_BP1 PF00638.18 KIY74359.1 - 3.4e-11 43.4 0.0 6.4e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain Nucleoporin_FG PF13634.6 KIY74359.1 - 2.6e-06 28.2 17.6 2.6e-06 28.2 17.6 5.3 2 1 2 5 5 5 3 Nucleoporin FG repeat region WH1 PF00568.23 KIY74359.1 - 0.12 12.3 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 WH1 domain RabGAP-TBC PF00566.18 KIY74360.1 - 1.5e-53 181.6 0.1 2e-53 181.3 0.1 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain IL34 PF15036.6 KIY74360.1 - 0.048 13.7 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Interleukin 34 RraA-like PF03737.15 KIY74362.1 - 5.8e-28 97.9 0.1 7.5e-28 97.6 0.1 1.1 1 0 0 1 1 1 1 Aldolase/RraA IMS PF00817.20 KIY74363.1 - 2.2e-46 157.6 0.0 4.8e-46 156.5 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 KIY74363.1 - 1.3e-15 58.1 0.1 3.1e-15 56.9 0.1 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 KIY74363.1 - 2e-07 30.9 0.0 4.7e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif Tropomodulin PF03250.14 KIY74363.1 - 0.19 11.8 1.8 12 6.0 0.1 3.0 3 0 0 3 3 3 0 Tropomodulin Lipase3_N PF03893.16 KIY74364.1 - 0.13 12.3 0.3 0.41 10.7 0.1 1.9 2 0 0 2 2 2 0 Lipase 3 N-terminal region Apt1 PF10351.9 KIY74364.1 - 5.6 5.7 8.1 7.2 5.3 8.1 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Rad21_Rec8_N PF04825.13 KIY74365.1 - 5.8e-36 123.0 0.0 1e-35 122.2 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 KIY74365.1 - 1.3e-14 53.2 0.0 2.3e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein PPR_3 PF13812.6 KIY74366.1 - 1.2e-23 82.9 0.1 8.6e-07 28.9 0.0 5.2 4 1 0 5 5 5 3 Pentatricopeptide repeat domain PPR_2 PF13041.6 KIY74366.1 - 1.2e-21 76.6 0.0 0.0068 16.6 0.1 7.9 5 2 3 8 8 8 5 PPR repeat family PPR_long PF17177.4 KIY74366.1 - 4.1e-14 52.5 0.1 0.00035 20.0 0.0 4.9 2 2 3 5 5 5 4 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 KIY74366.1 - 0.00016 21.3 0.9 1.5 8.6 0.0 4.6 5 0 0 5 5 5 2 PPR repeat PPR PF01535.20 KIY74366.1 - 0.00068 19.7 9.1 6.4 7.3 0.1 7.7 9 0 0 9 9 9 1 PPR repeat MNE1 PF13762.6 KIY74366.1 - 0.01 15.8 1.0 1.9 8.5 0.1 2.7 3 0 0 3 3 3 0 Mitochondrial splicing apparatus component NETI PF14044.6 KIY74366.1 - 0.016 14.9 0.5 0.68 9.7 0.1 2.7 3 0 0 3 3 3 0 NETI protein GMP_synt_C PF00958.22 KIY74366.1 - 0.039 14.0 0.0 27 4.9 0.0 3.7 3 2 2 5 5 5 0 GMP synthase C terminal domain TPR_19 PF14559.6 KIY74366.1 - 0.068 13.7 0.5 53 4.4 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat NOT2_3_5 PF04153.18 KIY74368.1 - 1.5e-30 106.0 0.1 1.5e-30 106.0 0.1 1.9 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family DUF4450 PF14614.6 KIY74368.1 - 0.018 14.6 1.2 0.037 13.6 1.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4450) Stanniocalcin PF03298.13 KIY74369.1 - 1.6e-06 27.6 0.0 1.9e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 Stanniocalcin family Asp PF00026.23 KIY74371.1 - 4.9e-81 272.6 0.1 5.9e-81 272.3 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIY74371.1 - 1.6e-13 51.3 1.0 3.5e-07 30.6 0.1 2.6 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal BAG PF02179.16 KIY74372.1 - 1.2e-08 35.2 0.0 1.9e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 BAG domain PTPLA PF04387.14 KIY74373.1 - 4.6e-56 189.1 8.3 8.1e-56 188.3 8.3 1.4 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA OTCace PF00185.24 KIY74376.1 - 3.5e-48 163.6 0.0 5.2e-48 163.1 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 KIY74376.1 - 4.9e-44 149.9 0.0 7.4e-44 149.4 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OCD_Mu_crystall PF02423.15 KIY74376.1 - 0.11 11.4 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family Acyltransferase PF01553.21 KIY74377.1 - 3.4e-13 49.4 0.0 7.1e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase Cauli_VI PF01693.16 KIY74377.1 - 0.027 14.8 0.1 0.059 13.7 0.1 1.5 1 0 0 1 1 1 0 Caulimovirus viroplasmin FA_desaturase PF00487.24 KIY74377.1 - 2.5 7.9 10.0 6.5 6.5 10.0 1.7 1 0 0 1 1 1 0 Fatty acid desaturase ABC_tran PF00005.27 KIY74378.1 - 7.3e-48 162.6 0.0 3.1e-27 95.8 0.0 3.6 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KIY74378.1 - 5.5e-15 56.0 1.2 0.0075 16.1 0.8 4.2 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KIY74378.1 - 4.5e-12 45.9 0.0 0.0004 19.9 0.0 3.9 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain Chromo PF00385.24 KIY74378.1 - 1.5e-08 34.4 0.3 3e-08 33.4 0.3 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_23 PF13476.6 KIY74378.1 - 1.9e-07 31.8 0.0 0.0027 18.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KIY74378.1 - 1e-06 28.4 0.9 0.04 13.6 0.2 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KIY74378.1 - 4.2e-06 26.8 0.1 0.017 15.2 0.0 2.8 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_18 PF13238.6 KIY74378.1 - 9e-06 26.3 0.0 0.063 13.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KIY74378.1 - 2e-05 24.9 0.1 0.26 11.6 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_28 PF13521.6 KIY74378.1 - 2.2e-05 24.8 0.1 0.25 11.6 0.0 2.8 3 0 0 3 3 2 2 AAA domain DUF87 PF01935.17 KIY74378.1 - 0.00011 22.4 0.0 0.42 10.7 0.0 2.7 2 0 0 2 2 2 2 Helicase HerA, central domain RsgA_GTPase PF03193.16 KIY74378.1 - 0.00011 22.1 0.0 0.079 12.9 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KIY74378.1 - 0.00014 22.3 1.2 0.89 9.9 0.0 3.6 3 1 0 3 3 3 2 AAA ATPase domain HEAT PF02985.22 KIY74378.1 - 0.0006 19.8 6.3 2.8 8.4 0.0 5.3 5 0 0 5 5 4 1 HEAT repeat MeaB PF03308.16 KIY74378.1 - 0.00078 18.5 0.4 0.57 9.1 0.1 2.4 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB NACHT PF05729.12 KIY74378.1 - 0.0013 18.7 0.4 0.3 11.0 0.1 3.2 3 1 0 3 3 3 1 NACHT domain AAA_24 PF13479.6 KIY74378.1 - 0.0013 18.5 0.2 1.4 8.6 0.1 2.8 3 0 0 3 3 2 1 AAA domain AAA_33 PF13671.6 KIY74378.1 - 0.0016 18.6 0.0 0.72 10.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KIY74378.1 - 0.0041 16.8 0.2 2.9 7.5 0.0 3.3 4 0 0 4 4 3 1 AAA domain Tudor-knot PF11717.8 KIY74378.1 - 0.0077 16.1 0.3 0.016 15.1 0.3 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain AAA_13 PF13166.6 KIY74378.1 - 0.0091 14.7 0.0 1.1 7.8 0.0 2.4 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 KIY74378.1 - 0.011 16.1 0.0 5.6 7.4 0.0 2.8 2 0 0 2 2 2 0 RNA helicase Roc PF08477.13 KIY74378.1 - 0.011 15.9 0.0 8.1 6.7 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_14 PF13173.6 KIY74378.1 - 0.011 15.7 0.1 7 6.7 0.0 2.9 2 1 0 2 2 2 0 AAA domain G-alpha PF00503.20 KIY74378.1 - 0.011 14.9 0.0 0.06 12.5 0.0 2.0 2 0 0 2 2 2 0 G-protein alpha subunit 4HB PF17947.1 KIY74378.1 - 0.016 15.2 0.0 0.057 13.5 0.0 1.9 2 0 0 2 2 1 0 Four helical bundle domain MMS19_C PF12460.8 KIY74378.1 - 0.017 14.2 0.2 0.67 9.0 0.1 2.2 2 0 0 2 2 2 0 RNAPII transcription regulator C-terminal DNA_pol_phi PF04931.13 KIY74378.1 - 0.021 12.9 0.0 0.031 12.4 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase phi CLASP_N PF12348.8 KIY74378.1 - 0.021 14.4 0.0 2.6 7.5 0.0 2.5 1 1 0 2 2 2 0 CLASP N terminal ATP_bind_1 PF03029.17 KIY74378.1 - 0.033 14.0 0.1 10 5.8 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_7 PF12775.7 KIY74378.1 - 0.047 13.2 0.0 1 8.8 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_15 PF13175.6 KIY74378.1 - 0.048 13.4 1.7 1.8 8.2 0.3 2.2 2 0 0 2 2 2 0 AAA ATPase domain Arf PF00025.21 KIY74378.1 - 0.056 12.9 0.0 2.1 7.8 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family Ploopntkinase3 PF18751.1 KIY74378.1 - 0.065 13.1 0.0 3.3 7.6 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 IFRD PF05004.13 KIY74378.1 - 0.068 12.3 0.1 0.24 10.5 0.1 1.9 2 0 0 2 2 1 0 Interferon-related developmental regulator (IFRD) AAA_27 PF13514.6 KIY74378.1 - 0.073 12.7 0.0 3.9 7.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 KIY74378.1 - 0.085 12.1 0.0 4.9 6.3 0.0 2.9 3 0 0 3 3 3 0 KAP family P-loop domain PduV-EutP PF10662.9 KIY74378.1 - 0.089 12.5 0.0 8.3 6.1 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATPase_2 PF01637.18 KIY74378.1 - 0.095 12.6 0.6 27 4.6 0.0 3.0 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 KIY74378.1 - 0.12 11.5 0.0 6.5 5.9 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain cobW PF02492.19 KIY74378.1 - 0.13 11.8 0.1 17 4.9 0.1 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Dopey_N PF04118.14 KIY74378.1 - 0.13 11.3 0.0 14 4.7 0.0 2.3 1 1 0 2 2 2 0 Dopey, N-terminal DUF3584 PF12128.8 KIY74378.1 - 0.26 8.8 2.1 4.5 4.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) HEAT_EZ PF13513.6 KIY74378.1 - 1.2 9.7 6.0 16 6.2 0.5 4.7 4 2 1 5 5 4 0 HEAT-like repeat Homeodomain PF00046.29 KIY74379.1 - 9.3e-17 60.6 4.4 1.6e-16 59.8 4.4 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KIY74379.1 - 0.0002 21.2 0.4 0.0002 21.2 0.4 2.0 2 0 0 2 2 2 1 Homeobox KN domain YdaS_antitoxin PF15943.5 KIY74379.1 - 0.16 11.9 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Pkinase PF00069.25 KIY74380.1 - 1.2e-60 205.1 0.1 2.5e-38 131.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KIY74380.1 - 4.9e-26 91.6 0.1 1.1e-16 60.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KIY74380.1 - 8.4e-05 22.0 0.1 0.0012 18.2 0.0 2.5 3 0 0 3 3 3 1 Kinase-like APH PF01636.23 KIY74380.1 - 0.0014 18.6 0.3 0.0044 17.0 0.3 1.9 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KIY74380.1 - 0.0088 15.0 0.1 0.013 14.5 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KIY74380.1 - 0.038 12.8 0.0 0.07 11.9 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase zf-C2H2 PF00096.26 KIY74381.1 - 1.9e-15 56.3 5.0 5.1e-08 32.9 0.6 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIY74381.1 - 2.3e-11 43.5 4.2 6.4e-06 26.6 0.5 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KIY74381.1 - 2e-08 34.3 12.3 1.4e-05 25.3 0.2 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KIY74381.1 - 7.3e-06 26.1 0.8 3e-05 24.2 0.4 2.0 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 KIY74381.1 - 1.7e-05 24.6 1.3 0.0079 16.1 0.1 2.3 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.6 KIY74381.1 - 0.00015 21.7 4.3 0.0029 17.5 0.8 2.3 2 0 0 2 2 2 1 C2H2-type zinc finger zf-met PF12874.7 KIY74381.1 - 0.0011 19.2 0.4 0.0011 19.2 0.4 2.2 3 1 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2HE PF16278.5 KIY74381.1 - 0.0017 18.8 1.0 0.014 15.9 0.1 2.0 1 1 1 2 2 2 1 C2HE / C2H2 / C2HC zinc-binding finger Zn_ribbon_SprT PF17283.2 KIY74381.1 - 0.0029 17.5 2.6 0.15 12.0 0.1 2.1 2 0 0 2 2 2 1 SprT-like zinc ribbon domain zf-BED PF02892.15 KIY74381.1 - 0.0034 17.4 3.2 0.014 15.4 0.2 2.2 1 1 1 2 2 2 1 BED zinc finger Zn-ribbon_8 PF09723.10 KIY74381.1 - 0.0034 17.5 1.4 1.2 9.4 1.0 2.1 1 1 1 2 2 2 2 Zinc ribbon domain zf-C2H2_11 PF16622.5 KIY74381.1 - 0.0037 17.0 4.2 0.28 11.0 0.2 2.2 2 0 0 2 2 2 2 zinc-finger C2H2-type DUF3268 PF11672.8 KIY74381.1 - 0.014 15.7 0.2 0.015 15.7 0.2 1.1 1 0 0 1 1 1 0 zinc-finger-containing domain zf-C2H2_aberr PF17017.5 KIY74381.1 - 0.028 14.6 0.1 0.037 14.2 0.0 1.4 1 1 0 1 1 1 0 Aberrant zinc-finger zf-Di19 PF05605.12 KIY74381.1 - 0.049 13.9 0.4 0.058 13.7 0.4 1.2 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 KIY74381.1 - 0.07 13.5 0.3 0.5 10.7 0.0 1.9 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf_C2HC_14 PF18574.1 KIY74381.1 - 0.98 9.3 6.3 1.7 8.5 0.8 2.5 2 1 0 2 2 2 0 C2HC Zing finger domain zf-H2C2_5 PF13909.6 KIY74381.1 - 1.9 8.3 12.2 1.6 8.6 1.0 3.0 3 0 0 3 3 3 0 C2H2-type zinc-finger domain BolA PF01722.18 KIY74382.1 - 9.3e-26 89.9 0.5 1.1e-25 89.7 0.5 1.1 1 0 0 1 1 1 1 BolA-like protein DNA_ligase_A_M PF01068.21 KIY74383.1 - 3.8e-40 137.7 0.1 3.1e-38 131.5 0.0 2.2 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KIY74383.1 - 2.2e-33 116.0 0.0 5.3e-33 114.8 0.0 1.7 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 KIY74383.1 - 2.1e-16 60.3 0.0 6.3e-16 58.8 0.0 1.9 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region zf-C2H2 PF00096.26 KIY74384.1 - 5.5e-11 42.3 9.3 2.5e-05 24.5 0.1 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIY74384.1 - 4.3e-07 30.2 8.7 0.004 17.9 4.2 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KIY74384.1 - 2.5e-06 27.6 8.0 5.7e-06 26.5 0.9 3.0 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KIY74384.1 - 0.00026 21.2 2.8 0.0049 17.1 1.0 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KIY74384.1 - 0.067 13.6 2.5 11 6.5 0.0 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KIY74384.1 - 0.29 11.2 7.4 0.85 9.7 2.5 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger Acetyltransf_1 PF00583.25 KIY74385.1 - 3.3e-11 43.4 0.0 4.2e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KIY74385.1 - 1.3e-07 31.9 0.0 2.2e-07 31.2 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KIY74385.1 - 2.6e-06 27.4 0.0 3.5e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KIY74385.1 - 6.5e-06 26.4 0.0 8e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KIY74385.1 - 0.00068 19.5 0.0 0.0011 18.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 KIY74385.1 - 0.076 12.7 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Complex1_49kDa PF00346.19 KIY74385.1 - 0.16 11.1 0.0 0.18 10.8 0.0 1.1 1 0 0 1 1 1 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit Pkinase PF00069.25 KIY74388.1 - 3.1e-60 203.8 0.0 3.8e-60 203.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY74388.1 - 2.5e-35 122.0 0.0 3.2e-35 121.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KIY74388.1 - 0.00018 20.9 0.0 0.0022 17.4 0.0 2.3 2 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KIY74388.1 - 0.0018 17.2 0.0 0.0029 16.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 KIY74388.1 - 0.11 11.5 0.0 0.17 10.9 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 DUF3659 PF12396.8 KIY74388.1 - 0.28 11.1 1.6 0.57 10.1 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3659) Zn_clus PF00172.18 KIY74389.1 - 6.5e-08 32.6 8.2 1.1e-07 31.8 8.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cyclin PF08613.11 KIY74391.1 - 1.8e-05 25.2 0.0 0.0051 17.2 0.0 2.5 2 0 0 2 2 2 2 Cyclin Cyclin_N PF00134.23 KIY74391.1 - 0.072 12.8 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Cyclin, N-terminal domain MoeA_C PF03454.15 KIY74391.1 - 0.11 12.7 0.1 0.4 10.9 0.0 2.0 2 0 0 2 2 2 0 MoeA C-terminal region (domain IV) SLT PF01464.20 KIY74392.1 - 5.4e-09 35.7 1.7 5.4e-09 35.7 0.0 2.0 3 0 0 3 3 3 1 Transglycosylase SLT domain PPP5 PF08321.12 KIY74393.1 - 2.3e-29 101.5 0.0 3.6e-29 100.9 0.0 1.3 1 0 0 1 1 1 1 PPP5 TPR repeat region Metallophos PF00149.28 KIY74393.1 - 2.6e-25 90.1 0.2 4.4e-25 89.4 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_1 PF00515.28 KIY74393.1 - 2.3e-06 27.2 0.4 1e-05 25.1 0.1 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 KIY74393.1 - 0.00083 19.3 0.4 0.0024 17.8 0.1 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 KIY74393.1 - 0.0019 18.3 0.1 0.0038 17.3 0.1 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.6 KIY74393.1 - 0.016 15.5 0.1 0.38 11.2 0.1 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 KIY74393.1 - 0.019 14.7 0.2 6.3 6.6 0.0 2.6 2 0 0 2 2 2 0 TPR repeat TPR_15 PF13429.6 KIY74393.1 - 0.024 13.9 0.1 0.038 13.2 0.1 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_19 PF14559.6 KIY74393.1 - 0.07 13.7 0.2 1.4 9.4 0.0 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 KIY74393.1 - 0.079 13.2 0.1 0.48 10.8 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat AbrB_C PF18277.1 KIY74393.1 - 0.083 12.5 0.0 0.3 10.7 0.0 2.0 2 0 0 2 2 2 0 AbrB C-terminal domain TPR_6 PF13174.6 KIY74393.1 - 0.091 13.4 0.1 0.22 12.3 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 KIY74394.1 - 0.00045 19.9 2.0 0.37 10.7 0.3 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 KIY74394.1 - 0.001 19.3 0.9 0.0018 18.5 0.9 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.6 KIY74394.1 - 0.0032 17.1 0.1 0.0048 16.6 0.1 1.4 1 0 0 1 1 1 1 TPR repeat TPR_16 PF13432.6 KIY74394.1 - 0.006 17.2 2.2 0.006 17.2 2.2 1.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 KIY74394.1 - 0.0098 15.9 3.1 1.9 8.8 0.1 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat DUF3614 PF12267.8 KIY74394.1 - 0.021 15.3 0.1 0.026 15.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3614) TPR_14 PF13428.6 KIY74394.1 - 0.11 13.4 0.1 0.17 12.8 0.1 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat SNF2_N PF00176.23 KIY74395.1 - 1e-70 238.2 0.5 2.6e-70 236.9 0.5 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 KIY74395.1 - 1.8e-35 121.4 3.7 2.7e-35 120.8 0.8 2.8 2 0 0 2 2 2 1 SLIDE HAND PF09110.11 KIY74395.1 - 1.3e-27 96.8 3.9 1.3e-27 96.8 3.9 4.1 3 1 0 3 3 3 1 HAND Helicase_C PF00271.31 KIY74395.1 - 1.2e-18 67.5 0.1 2.3e-17 63.3 0.0 2.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KIY74395.1 - 7.4e-12 45.6 0.0 4.4e-11 43.1 0.0 2.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KIY74395.1 - 2.2e-06 27.1 0.7 2e-05 23.9 0.0 2.8 2 1 1 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 KIY74395.1 - 1e-05 25.4 0.0 3.3e-05 23.7 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase DBINO PF13892.6 KIY74395.1 - 0.0016 18.8 3.1 0.0016 18.8 3.1 3.9 5 0 0 5 5 5 1 DNA-binding domain AAA_14 PF13173.6 KIY74395.1 - 0.0051 16.8 1.1 0.029 14.4 0.1 2.8 2 0 0 2 2 2 1 AAA domain CDRT4 PF15213.6 KIY74395.1 - 0.07 13.7 4.1 2.4 8.8 0.1 3.6 3 0 0 3 3 3 0 CMT1A duplicated region transcript 4 protein RRM_1 PF00076.22 KIY74396.1 - 8.8e-12 44.7 0.0 1.8e-05 24.4 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Surp PF01805.20 KIY74396.1 - 1.5e-08 34.5 0.1 4.3e-08 33.0 0.1 1.8 1 0 0 1 1 1 1 Surp module CTD_bind PF04818.13 KIY74396.1 - 0.0014 19.4 0.0 0.0036 18.1 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase II-binding domain. RRM_7 PF16367.5 KIY74396.1 - 0.019 15.1 0.0 0.047 13.8 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif CTK3 PF12243.8 KIY74396.1 - 0.15 12.0 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 DUF1509 PF07420.11 KIY74396.1 - 3.2 6.6 11.4 7.2 5.5 11.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) CBP_BcsO PF17037.5 KIY74397.1 - 6.1 7.0 12.0 0.058 13.6 2.7 1.9 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsO Peptidase_M13_N PF05649.13 KIY74398.1 - 1.6e-100 337.5 0.0 2.1e-100 337.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 KIY74398.1 - 2.7e-61 206.8 0.0 5.4e-61 205.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M13 DUF4249 PF14054.6 KIY74398.1 - 0.075 12.7 0.0 3.1 7.4 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4249) DUF247 PF03140.15 KIY74398.1 - 0.076 12.2 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Plant protein of unknown function ANAPC_CDC26 PF10471.9 KIY74399.1 - 0.11 13.3 9.9 0.49 11.3 9.9 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 PRA1 PF03208.19 KIY74400.1 - 1.7e-35 121.7 1.2 2e-35 121.5 1.2 1.0 1 0 0 1 1 1 1 PRA1 family protein MPS-4 PF17523.2 KIY74400.1 - 0.0015 18.6 0.3 0.0031 17.6 0.3 1.6 1 0 0 1 1 1 1 MinK-related peptide, potassium channel accessory sub-unit protein 4 PSI_PsaJ PF01701.18 KIY74400.1 - 5 7.7 11.6 1.4 9.5 0.9 3.0 2 1 1 3 3 3 0 Photosystem I reaction centre subunit IX / PsaJ zf-SNAP50_C PF12251.8 KIY74401.1 - 3.4e-24 85.6 0.0 4.8e-24 85.2 0.0 1.1 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal Zn_clus PF00172.18 KIY74402.1 - 0.00084 19.4 10.5 0.0014 18.7 10.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Allantoicase PF03561.15 KIY74403.1 - 2.4e-85 283.8 0.0 3.5e-43 147.0 0.0 2.3 2 0 0 2 2 2 2 Allantoicase repeat Ureidogly_lyase PF04115.12 KIY74403.1 - 2.3e-44 151.4 0.0 3.2e-44 150.9 0.0 1.2 1 0 0 1 1 1 1 Ureidoglycolate lyase LRR_RI_capping PF18779.1 KIY74403.1 - 0.095 12.4 0.1 1.9 8.2 0.0 2.3 2 0 0 2 2 2 0 Capping Ribonuclease inhibitor Leucine Rich Repeat COG7 PF10191.9 KIY74404.1 - 7e-78 262.7 1.6 2.4e-46 158.4 0.4 3.0 2 1 0 2 2 2 2 Golgi complex component 7 (COG7) Sec10 PF07393.11 KIY74404.1 - 5.9e-05 21.7 0.0 0.00012 20.7 0.0 1.4 1 0 0 1 1 1 1 Exocyst complex component Sec10 MutS_III PF05192.18 KIY74404.1 - 0.053 13.7 3.2 2.4 8.3 0.1 2.8 2 1 0 2 2 2 0 MutS domain III AOX PF01786.17 KIY74404.1 - 0.12 12.0 0.1 0.27 10.8 0.1 1.5 1 0 0 1 1 1 0 Alternative oxidase Rhodanese PF00581.20 KIY74405.1 - 9e-11 42.3 0.0 1.8e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain HAMP PF00672.25 KIY74406.1 - 4e-07 30.3 4.4 0.00024 21.4 0.4 3.1 3 1 1 4 4 4 2 HAMP domain N_Asn_amidohyd PF14736.6 KIY74406.1 - 0.024 13.8 0.7 0.043 13.0 0.4 1.5 2 0 0 2 2 2 0 Protein N-terminal asparagine amidohydrolase zf-C4pol PF14260.6 KIY74406.1 - 0.18 12.3 0.1 0.49 10.9 0.1 1.8 1 0 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta DUF948 PF06103.11 KIY74406.1 - 0.35 11.1 3.2 14 6.1 0.0 3.6 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF3844 PF12955.7 KIY74407.1 - 3.7e-31 107.4 5.1 5.6e-31 106.8 5.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) EGF_2 PF07974.13 KIY74407.1 - 7 7.1 9.0 16 6.0 9.0 1.6 1 0 0 1 1 1 0 EGF-like domain Chs7 PF12271.8 KIY74408.1 - 3.3e-112 374.5 21.5 3.9e-112 374.3 21.5 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone CRC_subunit PF08624.10 KIY74409.1 - 1.2e-42 145.6 0.0 1.7e-42 145.0 0.0 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit Fungal_trans PF04082.18 KIY74410.1 - 3e-23 82.2 0.0 6e-23 81.2 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KIY74410.1 - 7.8e-08 32.3 9.4 7.8e-08 32.3 9.4 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RNase_H2-Ydr279 PF09468.10 KIY74411.1 - 3.3e-16 59.9 0.4 5.4e-16 59.2 0.1 1.5 2 0 0 2 2 2 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 KIY74411.1 - 6.5e-13 48.7 0.0 1.4e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 Ydr279p protein triple barrel domain COesterase PF00135.28 KIY74413.1 - 6.7e-95 318.9 0.0 8.2e-95 318.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KIY74413.1 - 6.1e-09 36.1 0.7 2.9e-07 30.5 0.1 3.2 2 1 1 3 3 3 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KIY74413.1 - 0.11 11.9 0.1 0.11 11.9 0.1 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase family Mit_ribos_Mrp51 PF11709.8 KIY74413.1 - 0.2 11.2 0.0 0.28 10.8 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit ATP-sulfurylase PF01747.17 KIY74414.1 - 6.3e-88 293.8 0.1 8.8e-88 293.3 0.1 1.2 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.6 KIY74414.1 - 1.6e-52 177.4 0.0 2.6e-52 176.7 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain APS_kinase PF01583.20 KIY74414.1 - 3.4e-38 131.0 0.0 5e-38 130.5 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase CPT PF07931.12 KIY74414.1 - 0.011 15.6 0.0 3.4 7.5 0.0 2.4 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein MmgE_PrpD PF03972.14 KIY74416.1 - 3.9e-155 516.7 0.0 4.6e-155 516.5 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family Bromodomain PF00439.25 KIY74417.1 - 4.4e-22 78.0 0.1 5.5e-14 52.0 0.1 2.4 2 0 0 2 2 2 2 Bromodomain BAH PF01426.18 KIY74417.1 - 8.9e-20 70.8 0.1 3.5e-19 68.8 0.0 2.0 3 0 0 3 3 3 1 BAH domain Cu-oxidase PF00394.22 KIY74418.1 - 5.2e-47 159.9 0.0 5.5e-44 150.1 0.0 2.6 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 KIY74418.1 - 8.7e-38 129.2 0.9 7.7e-35 119.6 0.0 3.6 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KIY74418.1 - 1.1e-37 128.7 0.1 9.3e-37 125.7 0.0 2.4 2 0 0 2 2 2 1 Multicopper oxidase KH_1 PF00013.29 KIY74419.1 - 1.6e-90 296.9 23.4 1.7e-12 46.9 0.0 13.4 14 1 0 14 14 14 10 KH domain KH_2 PF07650.17 KIY74419.1 - 2.7e-10 39.9 24.0 0.07 13.0 0.9 7.8 7 2 1 8 8 8 5 KH domain SLS PF14611.6 KIY74419.1 - 2.4e-08 34.1 21.3 0.09 12.6 0.2 7.7 4 2 3 8 8 8 4 Mitochondrial inner-membrane-bound regulator KH_5 PF13184.6 KIY74419.1 - 0.0046 17.0 14.4 1.1 9.5 0.5 5.8 5 0 0 5 5 5 2 NusA-like KH domain MOEP19 PF16005.5 KIY74419.1 - 0.1 12.6 0.0 4.4 7.4 0.0 3.3 3 0 0 3 3 3 0 KH-like RNA-binding domain TBCC_N PF16752.5 KIY74419.1 - 0.11 12.9 0.9 16 6.0 0.1 3.2 3 0 0 3 3 3 0 Tubulin-specific chaperone C N-terminal domain DUF4510 PF14971.6 KIY74419.1 - 0.15 12.4 3.7 0.25 11.7 0.1 2.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4510) Secretin_N PF03958.17 KIY74419.1 - 0.23 11.9 6.9 0.72 10.3 0.1 4.5 5 0 0 5 5 5 0 Bacterial type II/III secretion system short domain KH_4 PF13083.6 KIY74419.1 - 1.2 9.0 17.0 5.8 6.9 0.0 6.9 8 0 0 8 8 8 0 KH domain ERO1 PF04137.15 KIY74420.1 - 2.2e-123 412.0 0.0 2.7e-123 411.7 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) zf-C2H2 PF00096.26 KIY74421.1 - 3.4e-12 46.1 14.0 0.00031 21.0 0.4 3.3 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KIY74421.1 - 2e-07 31.3 12.7 0.013 16.2 0.3 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KIY74421.1 - 5.4e-07 29.8 10.7 0.00022 21.5 0.2 4.4 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 KIY74421.1 - 5.5e-05 23.1 7.4 0.0054 16.7 0.2 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KIY74421.1 - 0.0026 18.0 1.2 0.16 12.4 0.3 2.3 1 1 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 KIY74421.1 - 0.0076 16.6 5.5 0.86 10.1 0.1 3.4 3 0 0 3 3 3 2 Zinc-finger of C2H2 type FOXP-CC PF16159.5 KIY74421.1 - 0.048 14.3 14.1 0.93 10.2 6.2 3.6 2 1 2 4 4 4 0 FOXP coiled-coil domain zf-TRAF PF02176.18 KIY74421.1 - 0.056 14.1 4.2 0.062 14.0 1.1 2.1 1 1 1 2 2 2 0 TRAF-type zinc finger zf-BED PF02892.15 KIY74421.1 - 0.75 9.9 6.5 0.47 10.5 1.7 2.3 2 0 0 2 2 2 0 BED zinc finger zf-C2H2_jaz PF12171.8 KIY74421.1 - 0.92 9.9 5.5 2.5 8.5 0.0 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 KIY74421.1 - 0.94 9.8 6.8 3.7 7.9 3.2 2.3 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_11 PF16622.5 KIY74421.1 - 3.8 7.4 9.9 0.51 10.2 0.2 2.9 3 0 0 3 3 3 0 zinc-finger C2H2-type TPR_1 PF00515.28 KIY74422.1 - 1.7e-22 78.2 5.0 6.8e-05 22.5 0.1 4.5 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 KIY74422.1 - 1.7e-17 62.0 7.9 0.00078 19.4 0.2 4.8 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_17 PF13431.6 KIY74422.1 - 4.7e-15 54.8 4.2 0.039 14.3 0.1 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 KIY74422.1 - 6.8e-14 52.2 7.0 3e-06 27.8 1.6 4.4 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 KIY74422.1 - 1.6e-12 47.7 9.0 7.9e-06 26.3 1.3 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 KIY74422.1 - 5.3e-12 45.0 5.8 0.043 14.0 0.2 4.9 5 0 0 5 5 4 4 Tetratricopeptide repeat TPR_14 PF13428.6 KIY74422.1 - 8.6e-12 44.8 8.4 0.002 18.8 0.1 5.4 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 KIY74422.1 - 8.7e-11 41.3 6.3 0.00047 19.8 0.2 4.8 2 2 3 5 5 5 3 TPR repeat TPR_12 PF13424.6 KIY74422.1 - 3.4e-10 40.1 7.6 9e-05 22.7 1.1 3.9 3 1 1 4 4 3 3 Tetratricopeptide repeat TPR_9 PF13371.6 KIY74422.1 - 5.5e-08 32.8 4.7 0.011 15.9 0.2 3.5 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_20 PF14561.6 KIY74422.1 - 2.1e-06 27.9 3.1 0.025 14.9 0.1 4.4 2 2 3 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 KIY74422.1 - 1.5e-05 24.7 2.5 0.18 11.9 0.0 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KIY74422.1 - 3.8e-05 23.8 0.9 0.0017 18.6 0.7 2.9 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.12 KIY74422.1 - 0.0013 18.7 1.7 5.3 7.1 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 KIY74422.1 - 0.013 16.0 2.5 1.6e+02 3.3 0.1 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 KIY74422.1 - 0.03 14.2 5.6 6.5 6.8 2.6 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 KIY74422.1 - 0.23 11.6 8.3 1.7 8.8 0.5 4.1 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain Abhydrolase_3 PF07859.13 KIY74423.1 - 3.4e-26 92.4 0.0 3.7e-19 69.4 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Asparaginase_2 PF01112.18 KIY74424.1 - 6.6e-48 163.3 0.1 8.8e-48 162.9 0.1 1.1 1 0 0 1 1 1 1 Asparaginase Tfb4 PF03850.14 KIY74425.1 - 5.7e-83 278.6 0.1 6.7e-83 278.3 0.1 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 zf-met2 PF12907.7 KIY74425.1 - 1.8 8.8 0.0 1.8 8.8 0.0 3.3 3 0 0 3 3 3 0 Zinc-binding COesterase PF00135.28 KIY74426.1 - 5.9e-54 183.8 0.0 7.6e-54 183.4 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KIY74426.1 - 9.9e-08 32.1 0.1 5.5e-07 29.7 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold SNF2_N PF00176.23 KIY74427.1 - 1.8e-63 214.4 0.4 3e-63 213.7 0.4 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF4208 PF13907.6 KIY74427.1 - 1.9e-24 85.9 0.9 8.4e-24 83.8 0.9 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4208) Helicase_C PF00271.31 KIY74427.1 - 1.8e-19 70.1 0.0 5.7e-19 68.5 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chromo PF00385.24 KIY74427.1 - 1.3e-16 60.3 7.5 1.5e-11 44.0 1.3 3.0 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.15 KIY74427.1 - 4.5e-09 36.5 0.0 1.9e-08 34.5 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Cdh1_DBD_1 PF18196.1 KIY74427.1 - 4e-07 30.4 0.3 4e-07 30.4 0.3 3.8 3 1 1 4 4 4 1 Chromodomain helicase DNA-binding domain 1 CDH1_2_SANT_HL1 PF18375.1 KIY74427.1 - 5.2e-06 27.0 1.9 1.5e-05 25.6 0.2 2.6 2 0 0 2 2 2 1 CDH1/2 SANT-Helical linker 1 DEAD PF00270.29 KIY74427.1 - 0.00024 20.9 0.2 0.0011 18.8 0.0 2.1 3 0 0 3 3 3 1 DEAD/DEAH box helicase Rubella_Capsid PF05750.11 KIY74427.1 - 0.16 11.6 3.9 0.41 10.2 3.9 1.6 1 0 0 1 1 1 0 Rubella capsid protein Amidohydro_1 PF01979.20 KIY74428.1 - 5.4e-14 52.3 0.1 8.5e-09 35.2 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 KIY74428.1 - 4.5e-11 42.9 0.1 0.00032 20.3 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family PD40 PF07676.12 KIY74428.1 - 5.3e-07 29.4 1.7 0.00035 20.4 0.1 4.3 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Zip PF02535.22 KIY74429.1 - 0.00024 20.4 0.2 0.00027 20.3 0.2 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter RseC_MucC PF04246.12 KIY74429.1 - 0.023 14.6 0.0 0.044 13.7 0.0 1.3 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC Apt1 PF10351.9 KIY74429.1 - 0.28 10.0 10.6 0.32 9.8 10.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Neur_chan_memb PF02932.16 KIY74429.1 - 0.86 9.6 5.3 1.3 9.0 5.3 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Paramyxo_ncap PF00973.19 KIY74429.1 - 2 7.3 6.9 2.6 6.9 6.9 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Presenilin PF01080.17 KIY74429.1 - 2.1 7.1 7.8 2.6 6.7 7.8 1.2 1 0 0 1 1 1 0 Presenilin BORG_CEP PF14957.6 KIY74429.1 - 3 9.0 9.8 8.4 7.6 9.8 1.8 1 1 0 1 1 1 0 Cdc42 effector Pheromone PF08015.11 KIY74429.1 - 3.9 8.6 6.5 13 6.9 5.1 2.6 2 1 0 2 2 2 0 Fungal mating-type pheromone Hid1 PF12722.7 KIY74429.1 - 5.1 5.1 12.9 6.4 4.8 12.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF1771 PF08590.10 KIY74429.1 - 9 6.7 13.9 0.15 12.4 6.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1771) DUF2156 PF09924.9 KIY74430.1 - 4e-14 52.3 0.0 6.2e-14 51.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) SMC_ScpB PF04079.16 KIY74430.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Segregation and condensation complex subunit ScpB BRE1 PF08647.11 KIY74431.1 - 5.6e-19 68.0 17.2 5.6e-19 68.0 17.2 8.1 5 3 2 7 7 5 2 BRE1 E3 ubiquitin ligase zf-C3HC4_3 PF13920.6 KIY74431.1 - 2.4e-07 30.5 9.3 5e-07 29.5 9.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KIY74431.1 - 5e-07 29.5 12.5 1.1e-06 28.4 12.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KIY74431.1 - 1.6e-06 28.1 7.5 3.3e-06 27.0 7.5 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KIY74431.1 - 2.4e-06 27.3 13.6 5.3e-06 26.2 13.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KIY74431.1 - 1.4e-05 24.9 13.1 3.4e-05 23.7 13.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 KIY74431.1 - 0.00017 21.8 6.9 0.00055 20.2 6.9 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KIY74431.1 - 0.00017 21.8 11.0 0.00033 20.9 11.0 1.5 1 0 0 1 1 1 1 Ring finger domain HMMR_N PF15905.5 KIY74431.1 - 0.00084 18.9 15.1 0.00084 18.9 15.1 5.4 4 1 1 5 5 5 1 Hyaluronan mediated motility receptor N-terminal Prok-RING_4 PF14447.6 KIY74431.1 - 0.00084 19.1 7.5 0.0017 18.2 7.5 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 KIY74431.1 - 0.00097 19.0 2.6 0.0022 17.8 2.6 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein Wtap PF17098.5 KIY74431.1 - 0.0056 16.6 3.4 0.0056 16.6 3.4 7.1 3 1 3 6 6 3 1 WTAP/Mum2p family TMEM192 PF14802.6 KIY74431.1 - 0.0076 15.4 2.8 0.022 13.9 2.8 1.8 1 0 0 1 1 1 1 TMEM192 family Tht1 PF04163.12 KIY74431.1 - 0.01 14.6 0.8 0.01 14.6 0.8 3.2 2 1 1 3 3 2 0 Tht1-like nuclear fusion protein zf-C3HC4_4 PF15227.6 KIY74431.1 - 0.045 13.9 8.1 0.095 12.9 8.1 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF1272 PF06906.11 KIY74431.1 - 0.094 12.8 5.9 0.33 11.1 5.9 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-Nse PF11789.8 KIY74431.1 - 0.11 12.3 5.0 0.24 11.3 5.0 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 KIY74431.1 - 0.55 10.1 8.2 1.3 8.9 7.2 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 KIY74431.1 - 0.99 9.5 4.4 2.3 8.3 4.4 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Slu7 PF11708.8 KIY74432.1 - 7.5e-108 360.4 15.2 7.5e-108 360.4 15.2 2.1 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC PF00098.23 KIY74432.1 - 0.71 10.1 3.6 1.3 9.2 3.6 1.4 1 0 0 1 1 1 0 Zinc knuckle Trs65 PF12735.7 KIY74433.1 - 2.3e-23 83.1 0.1 8.8e-12 45.1 0.1 3.2 2 1 1 3 3 3 3 TRAPP trafficking subunit Trs65 tRNA-synt_1 PF00133.22 KIY74434.1 - 1.3e-218 727.2 0.0 4.2e-218 725.5 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KIY74434.1 - 3.4e-26 92.0 0.1 7.1e-26 91.0 0.1 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KIY74434.1 - 1.6e-13 50.2 0.4 0.00036 19.4 0.1 3.8 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 KIY74434.1 - 0.025 13.9 0.0 0.066 12.5 0.0 1.7 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain AHSP PF09236.10 KIY74434.1 - 0.035 14.5 0.0 0.12 12.9 0.0 1.9 1 0 0 1 1 1 0 Alpha-haemoglobin stabilising protein Methyltransf_2 PF00891.18 KIY74434.1 - 0.18 11.1 0.1 0.4 10.0 0.1 1.5 1 0 0 1 1 1 0 O-methyltransferase domain BRCT PF00533.26 KIY74435.1 - 6.3e-30 103.4 0.1 1.7e-09 37.9 0.0 6.3 6 0 0 6 6 6 5 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KIY74435.1 - 4.4e-26 90.6 5.9 6.8e-18 64.4 0.1 4.5 4 0 0 4 4 4 3 twin BRCT domain BRCT_2 PF16589.5 KIY74435.1 - 7.5e-23 80.8 0.6 1.1e-06 28.9 0.0 6.1 6 0 0 6 6 6 5 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 KIY74435.1 - 1.7e-19 69.5 0.2 8.6e-18 64.1 0.0 3.4 3 1 1 4 4 4 1 Regulator of Ty1 transposition protein 107 BRCT domain LIG3_BRCT PF16759.5 KIY74435.1 - 1.1e-09 38.5 6.8 0.00022 21.5 0.1 4.0 4 0 0 4 4 4 2 DNA ligase 3 BRCT domain HALZ PF02183.18 KIY74436.1 - 0.0029 17.8 4.7 0.008 16.4 0.6 2.7 2 1 0 2 2 2 1 Homeobox associated leucine zipper GAS PF13851.6 KIY74436.1 - 0.0068 15.8 14.4 0.013 14.9 14.4 1.5 1 1 0 1 1 1 1 Growth-arrest specific micro-tubule binding OmpH PF03938.14 KIY74436.1 - 0.0094 16.3 16.7 0.023 15.0 12.7 2.0 1 1 1 2 2 2 2 Outer membrane protein (OmpH-like) PV-1 PF06637.11 KIY74436.1 - 0.021 13.7 19.2 0.36 9.6 0.6 2.1 1 1 1 2 2 2 0 PV-1 protein (PLVAP) APG6_N PF17675.1 KIY74436.1 - 0.035 14.6 22.0 0.14 12.7 3.4 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF2353 PF09789.9 KIY74436.1 - 0.035 13.4 14.3 0.043 13.2 14.3 1.1 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) CENP-F_leu_zip PF10473.9 KIY74436.1 - 0.058 13.4 16.6 0.11 12.5 16.6 1.6 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 UPF0242 PF06785.11 KIY74436.1 - 0.07 13.2 18.6 0.41 10.7 9.2 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Borrelia_lipo_1 PF05714.11 KIY74436.1 - 0.09 12.5 3.3 0.93 9.2 0.1 2.1 2 0 0 2 2 2 0 Borrelia burgdorferi virulent strain associated lipoprotein Spc7 PF08317.11 KIY74436.1 - 0.11 11.4 17.8 0.11 11.3 17.8 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF641 PF04859.12 KIY74436.1 - 0.12 12.7 9.9 0.086 13.2 1.4 2.6 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) Cnn_1N PF07989.11 KIY74436.1 - 0.24 11.6 12.4 0.28 11.4 2.4 3.0 1 1 2 3 3 3 0 Centrosomin N-terminal motif 1 PRKG1_interact PF15898.5 KIY74436.1 - 0.28 12.1 18.2 16 6.5 15.1 3.0 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain DUF1843 PF08898.10 KIY74436.1 - 0.58 10.7 0.0 0.58 10.7 0.0 3.0 2 1 0 3 3 3 0 Domain of unknown function (DUF1843) Rho_Binding PF08912.11 KIY74436.1 - 0.6 11.0 12.9 6.9 7.6 0.7 3.0 1 1 1 2 2 2 0 Rho Binding Sec34 PF04136.15 KIY74436.1 - 0.63 9.9 7.3 0.24 11.3 0.8 2.0 1 1 1 2 2 2 0 Sec34-like family CENP-H PF05837.12 KIY74436.1 - 0.74 10.2 19.5 2.3 8.7 2.0 2.1 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Spc24 PF08286.11 KIY74436.1 - 0.88 9.8 13.9 2 8.7 1.2 2.5 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 YabA PF06156.13 KIY74436.1 - 0.89 10.2 11.4 2.1 9.0 1.1 2.4 1 1 1 2 2 2 0 Initiation control protein YabA Csm1_N PF18504.1 KIY74436.1 - 1 9.8 15.8 1.6 9.1 1.0 3.2 1 1 1 3 3 3 0 Csm1 N-terminal domain MAD PF05557.13 KIY74436.1 - 1.2 7.5 21.8 1.6 7.0 14.2 2.0 1 1 1 2 2 2 0 Mitotic checkpoint protein JIP_LZII PF16471.5 KIY74436.1 - 1.2 9.3 11.3 0.53 10.5 1.1 2.7 2 1 0 2 2 2 0 JNK-interacting protein leucine zipper II Leu_zip PF15294.6 KIY74436.1 - 1.3 8.5 14.8 1.8 8.0 1.4 2.0 1 1 1 2 2 2 0 Leucine zipper DUF2968 PF11180.8 KIY74436.1 - 1.4 8.5 17.7 0.084 12.5 1.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) Jnk-SapK_ap_N PF09744.9 KIY74436.1 - 2.3 8.4 18.0 22 5.3 18.0 2.0 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 ADIP PF11559.8 KIY74436.1 - 2.9 7.9 19.3 2 8.5 2.0 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding SlyX PF04102.12 KIY74436.1 - 3.1 8.5 13.3 0.54 10.9 0.7 3.1 1 1 1 2 2 2 0 SlyX DHR10 PF18595.1 KIY74436.1 - 3.3 7.8 26.2 1.6 8.8 21.9 2.0 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain DUF4407 PF14362.6 KIY74436.1 - 5.8 6.2 18.3 9.9 5.4 18.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) ZapB PF06005.12 KIY74436.1 - 6.6 7.3 20.0 1.3e+02 3.1 8.3 3.0 1 1 1 2 2 2 0 Cell division protein ZapB DUF3584 PF12128.8 KIY74436.1 - 7.5 3.9 21.9 8.8 3.7 21.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Atg14 PF10186.9 KIY74436.1 - 9.1 5.3 16.2 12 4.9 16.2 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FUSC PF04632.12 KIY74436.1 - 9.3 4.6 13.1 11 4.4 13.1 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family HAD_2 PF13419.6 KIY74437.1 - 4.8e-10 39.8 0.0 8e-10 39.1 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KIY74437.1 - 3.1e-09 37.4 0.0 5.2e-09 36.7 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KIY74437.1 - 1.5e-06 28.2 0.0 2.2e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Pkinase PF00069.25 KIY74438.1 - 2.5e-53 181.2 0.0 3.2e-53 180.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY74438.1 - 8.3e-35 120.3 0.0 1.3e-34 119.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KIY74438.1 - 0.0074 15.3 0.0 0.012 14.6 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KIY74438.1 - 0.13 11.6 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Kinase-like MOZ_SAS PF01853.18 KIY74439.1 - 1.8e-78 262.3 0.2 3.1e-78 261.5 0.1 1.4 2 0 0 2 2 2 1 MOZ/SAS family zf-MYST PF17772.1 KIY74439.1 - 1e-21 76.3 1.4 2e-21 75.3 1.4 1.5 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 KIY74439.1 - 1.3e-17 63.4 0.0 3e-17 62.2 0.0 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 KIY74439.1 - 0.0011 19.3 0.0 0.0023 18.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIY74439.1 - 0.016 15.5 0.0 0.034 14.4 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Chromo PF00385.24 KIY74439.1 - 0.072 13.0 0.0 0.19 11.7 0.0 1.7 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain PAXIP1_C PF15364.6 KIY74439.1 - 0.18 12.1 4.7 0.47 10.8 4.7 1.7 1 0 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein Ndc1_Nup PF09531.10 KIY74439.1 - 1.9 7.0 3.5 2.6 6.7 3.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup FAM176 PF14851.6 KIY74439.1 - 2 8.1 4.3 4.4 7.0 4.3 1.5 1 0 0 1 1 1 0 FAM176 family LAG1-DNAbind PF09271.11 KIY74441.1 - 2.2e-46 158.2 0.0 3.2e-46 157.7 0.0 1.3 1 0 0 1 1 1 1 LAG1, DNA binding BTD PF09270.10 KIY74441.1 - 3.8e-17 62.9 0.7 2.5e-08 34.3 0.0 3.0 2 1 0 2 2 2 2 Beta-trefoil DNA-binding domain TIG PF01833.24 KIY74441.1 - 0.0013 18.7 0.0 0.004 17.2 0.0 1.8 1 0 0 1 1 1 1 IPT/TIG domain LppC PF04348.13 KIY74442.1 - 0.28 9.9 0.5 0.42 9.3 0.5 1.1 1 0 0 1 1 1 0 LppC putative lipoprotein OCD_Mu_crystall PF02423.15 KIY74443.1 - 2.8e-24 85.7 0.0 3.3e-24 85.4 0.0 1.0 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 KIY74443.1 - 0.0001 22.3 0.0 0.00036 20.6 0.0 2.0 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase DUF2370 PF10176.9 KIY74444.1 - 1.8e-41 142.2 1.1 1.6e-33 116.3 0.1 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF2370) UPF0061 PF02696.14 KIY74445.1 - 3.3e-95 319.6 0.0 3e-94 316.5 0.0 2.3 1 1 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family zf-GRF PF06839.12 KIY74446.1 - 0.0001 22.3 0.5 0.00021 21.3 0.5 1.6 1 0 0 1 1 1 1 GRF zinc finger Atg14 PF10186.9 KIY74447.1 - 0.0061 15.7 7.1 0.0061 15.7 7.1 1.5 2 0 0 2 2 2 1 Vacuolar sorting 38 and autophagy-related subunit 14 bZIP_1 PF00170.21 KIY74447.1 - 0.011 15.8 3.1 0.048 13.8 2.6 2.2 1 1 1 2 2 2 0 bZIP transcription factor CtIP_N PF10482.9 KIY74447.1 - 0.017 15.2 4.1 0.039 14.0 4.1 1.6 1 0 0 1 1 1 0 Tumour-suppressor protein CtIP N-terminal domain DUF724 PF05266.14 KIY74447.1 - 0.03 14.2 3.8 0.054 13.3 3.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) PKcGMP_CC PF16808.5 KIY74447.1 - 0.031 14.1 5.3 0.1 12.5 5.3 1.9 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase PHA_synth_III_E PF09712.10 KIY74447.1 - 0.041 13.0 0.1 0.07 12.2 0.1 1.5 1 1 0 1 1 1 0 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) Cep57_MT_bd PF06657.13 KIY74447.1 - 0.058 13.8 4.7 0.062 13.8 1.4 2.5 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Spc7 PF08317.11 KIY74447.1 - 0.066 12.1 6.5 0.1 11.4 6.5 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein VPS38 PF17649.1 KIY74447.1 - 0.13 11.1 3.0 0.18 10.6 3.0 1.1 1 0 0 1 1 1 0 Vacuolar protein sorting 38 CaMBD PF02888.16 KIY74447.1 - 0.19 12.0 3.2 2 8.7 3.7 2.3 1 1 1 2 2 2 0 Calmodulin binding domain Phlebovirus_NSM PF07246.11 KIY74447.1 - 0.19 11.1 4.3 0.29 10.5 4.3 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M FlaC_arch PF05377.11 KIY74447.1 - 0.22 12.0 1.9 0.54 10.7 1.2 2.0 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) RasGAP_C PF03836.15 KIY74447.1 - 0.27 11.4 4.2 0.51 10.5 4.2 1.4 1 0 0 1 1 1 0 RasGAP C-terminus SIN1 PF05422.12 KIY74447.1 - 0.3 11.7 4.7 0.15 12.7 2.3 1.8 1 1 1 2 2 2 0 Stress-activated map kinase interacting protein 1 (SIN1) DASH_Spc19 PF08287.11 KIY74447.1 - 0.34 10.8 8.5 0.079 12.8 4.9 1.7 2 0 0 2 2 2 0 Spc19 CENP-F_leu_zip PF10473.9 KIY74447.1 - 0.45 10.5 9.5 1.1 9.3 9.5 1.6 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Snapin_Pallidin PF14712.6 KIY74447.1 - 0.52 10.8 7.9 1 9.8 2.5 2.8 1 1 1 2 2 2 0 Snapin/Pallidin TMPIT PF07851.13 KIY74447.1 - 1.8 7.7 3.4 2.6 7.2 3.4 1.2 1 0 0 1 1 1 0 TMPIT-like protein AAA_13 PF13166.6 KIY74447.1 - 2.3 6.7 9.2 0.76 8.3 5.7 1.6 1 1 0 2 2 2 0 AAA domain DUF1664 PF07889.12 KIY74447.1 - 3.1 7.9 5.4 11 6.1 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) KxDL PF10241.9 KIY74447.1 - 3.8 7.8 8.4 1.9 8.9 1.3 2.7 3 1 1 4 4 2 0 Uncharacterized conserved protein YabA PF06156.13 KIY74447.1 - 4.1 8.1 5.7 7 7.3 5.0 1.8 1 1 0 1 1 1 0 Initiation control protein YabA ZapB PF06005.12 KIY74447.1 - 4.3 7.9 14.5 0.64 10.5 7.9 2.7 2 1 1 3 3 3 0 Cell division protein ZapB UPF0242 PF06785.11 KIY74447.1 - 7.8 6.5 11.3 14 5.8 11.3 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus BSD PF03909.17 KIY74448.1 - 3.3e-17 62.2 0.1 9.9e-13 47.9 0.1 2.6 2 0 0 2 2 2 2 BSD domain PH_TFIIH PF08567.11 KIY74448.1 - 1.8e-14 53.8 0.3 3.1e-14 53.1 0.3 1.4 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain Put_Phosphatase PF06888.12 KIY74449.1 - 1.7e-49 168.4 0.0 2e-49 168.1 0.0 1.0 1 0 0 1 1 1 1 Putative Phosphatase HAD PF12710.7 KIY74449.1 - 0.00098 19.6 0.3 0.005 17.3 0.3 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KIY74449.1 - 0.14 12.4 0.0 0.8 10.0 0.0 1.9 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Pkinase PF00069.25 KIY74450.1 - 1.6e-49 168.6 0.0 2.5e-49 168.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KIY74450.1 - 1.3e-20 73.8 0.0 2.1e-20 73.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KIY74450.1 - 3.2e-05 24.0 0.1 9.5e-05 22.4 0.1 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KIY74450.1 - 0.0033 17.1 0.0 0.0074 15.9 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 KIY74450.1 - 0.11 12.0 1.8 0.18 11.4 0.1 2.0 2 0 0 2 2 2 0 Choline/ethanolamine kinase CASP_C PF08172.12 KIY74451.1 - 1.3e-73 247.4 0.0 1.3e-73 247.4 0.0 3.8 2 1 0 3 3 3 1 CASP C terminal CtIP_N PF10482.9 KIY74451.1 - 0.021 14.9 1.9 0.021 14.9 1.9 4.7 4 2 1 5 5 5 0 Tumour-suppressor protein CtIP N-terminal domain DUF812 PF05667.11 KIY74451.1 - 0.069 12.0 49.0 0.23 10.3 24.2 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF812) DUF4407 PF14362.6 KIY74451.1 - 1.3 8.3 50.9 0.078 12.3 6.9 4.3 1 1 3 4 4 4 0 Domain of unknown function (DUF4407) Ribosomal_S9 PF00380.19 KIY74452.1 - 1.9e-40 138.1 0.0 3.5e-40 137.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Pro_isomerase PF00160.21 KIY74453.1 - 9e-49 165.8 0.1 1.1e-48 165.4 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DEAD PF00270.29 KIY74454.1 - 1.9e-40 138.5 0.0 3.5e-40 137.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KIY74454.1 - 1.3e-20 73.8 0.0 5.5e-19 68.6 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KIY74454.1 - 1.4e-16 60.4 0.8 3.2e-16 59.3 0.8 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KIY74454.1 - 0.0003 20.8 0.0 0.00066 19.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KIY74454.1 - 0.0011 18.3 0.0 0.0025 17.1 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase C2 PF00168.30 KIY74455.1 - 5e-12 46.0 0.0 9.7e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 C2 domain Asp PF00026.23 KIY74456.1 - 2.4e-29 102.8 0.1 1.7e-16 60.5 0.1 2.3 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 KIY74456.1 - 0.00011 22.6 0.2 0.00042 20.6 0.2 2.0 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal DUF3863 PF12979.7 KIY74456.1 - 0.044 12.7 0.0 0.071 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3863) Cadherin_C_2 PF16492.5 KIY74456.1 - 0.057 14.2 0.0 0.12 13.1 0.0 1.5 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal DPBB_1 PF03330.18 KIY74457.1 - 5.1e-06 26.7 0.0 1.3e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 Lytic transglycolase Bromodomain PF00439.25 KIY74458.1 - 1.2e-19 70.1 0.0 7e-13 48.5 0.0 2.4 2 0 0 2 2 2 2 Bromodomain Acetyltransf_10 PF13673.7 KIY74458.1 - 0.00018 21.4 0.1 0.00034 20.5 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KIY74458.1 - 0.00045 20.4 0.0 0.00099 19.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KIY74458.1 - 0.0025 18.2 0.3 0.005 17.2 0.3 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF2407_C PF13373.6 KIY74458.1 - 0.11 12.7 0.1 0.19 11.9 0.1 1.4 1 0 0 1 1 1 0 DUF2407 C-terminal domain 2-Hacid_dh_C PF02826.19 KIY74459.1 - 4.1e-45 153.3 0.0 6.5e-45 152.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KIY74459.1 - 8e-18 64.4 0.0 1.1e-17 64.0 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KIY74459.1 - 3.6e-05 24.0 0.0 0.00011 22.4 0.0 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase DUF3884 PF13024.6 KIY74459.1 - 0.0019 17.7 0.0 1.5 8.5 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF3884) Shikimate_DH PF01488.20 KIY74459.1 - 0.032 14.3 0.0 0.28 11.3 0.0 2.5 3 1 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase EXS PF03124.14 KIY74460.1 - 7.9e-102 341.0 9.1 9e-102 340.8 9.1 1.0 1 0 0 1 1 1 1 EXS family CHDCT2 PF08074.11 KIY74460.1 - 0.021 15.0 0.0 0.033 14.4 0.0 1.2 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain zf-C2H2_jaz PF12171.8 KIY74461.1 - 1.1e-05 25.6 0.1 1.9e-05 24.8 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding SNRNP27 PF08648.12 KIY74461.1 - 0.00015 21.8 3.5 0.00067 19.7 3.5 2.2 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins UNC-79 PF14776.6 KIY74461.1 - 0.0032 16.3 0.8 0.0043 15.9 0.8 1.2 1 0 0 1 1 1 1 Cation-channel complex subunit UNC-79 zf-met PF12874.7 KIY74461.1 - 0.005 17.2 0.4 0.0085 16.5 0.4 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-DBF PF07535.12 KIY74461.1 - 0.0091 16.1 0.1 0.016 15.3 0.1 1.4 1 0 0 1 1 1 1 DBF zinc finger Selenoprotein_S PF06936.11 KIY74461.1 - 0.32 10.8 15.3 0.035 13.9 2.9 2.1 2 0 0 2 2 2 0 Selenoprotein S (SelS) zf-C2H2 PF00096.26 KIY74461.1 - 0.38 11.3 1.5 0.69 10.5 1.5 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Cylindrobasidium_torrendii_FP15055_ss-10-Cylto1/GCA_000934385.1_Cylto1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Cylindrobasidium_torrendii_FP15055_ss-10-Cylto1/GCA_000934385.1_Cylto1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Cylindrobasidium_torrendii_FP15055_ss-10-Cylto1/GCA_000934385.1_Cylto1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Cylindrobasidium_torrendii_FP15055_ss-10-Cylto1/GCA_000934385.1_Cylto1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Sun Mar 24 18:57:03 2019 # [ok]